Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000164-TA|BGIBMGA000164-PA|IPR003961|Fibronectin, type
III, IPR007110|Immunoglobulin-like, IPR008957|Fibronectin, type
III-like fold, IPR003599|Immunoglobulin subtype,
IPR003598|Immunoglobulin subtype 2, IPR013162|CD80-like,
immunoglobulin C2-set, IPR013098|Immunoglobulin I-set,
IPR013151|Immunoglobulin
(838 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein. 223 2e-57
AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein. 223 2e-57
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 124 1e-27
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 123 2e-27
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 122 5e-27
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 122 5e-27
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 122 5e-27
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 122 5e-27
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 122 5e-27
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 122 5e-27
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 122 5e-27
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 122 5e-27
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 107 1e-22
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 107 1e-22
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 104 2e-21
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 103 3e-21
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 100 4e-20
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 100 4e-20
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 100 4e-20
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 100 4e-20
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 100 4e-20
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 98 1e-19
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 97 3e-19
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 96 4e-19
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 95 1e-18
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 94 2e-18
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 94 2e-18
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 94 2e-18
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 94 2e-18
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 94 2e-18
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 94 2e-18
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 94 2e-18
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 93 5e-18
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 93 5e-18
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 93 5e-18
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 93 5e-18
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 91 1e-17
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 91 1e-17
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 91 1e-17
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 91 1e-17
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 91 1e-17
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 91 1e-17
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 90 3e-17
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 89 5e-17
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 89 5e-17
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 89 6e-17
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 89 6e-17
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 89 8e-17
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 89 8e-17
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 88 1e-16
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 87 2e-16
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 87 2e-16
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 87 2e-16
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 87 2e-16
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 87 2e-16
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 87 2e-16
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 87 2e-16
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 87 2e-16
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 87 2e-16
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 87 2e-16
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 87 3e-16
AY358331-1|AAQ88697.1| 344|Homo sapiens HNT protein. 86 6e-16
AF126426-1|AAF37591.1| 344|Homo sapiens neurotrimin protein. 86 6e-16
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 85 7e-16
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 85 7e-16
EF043567-1|ABK34282.1| 355|Homo sapiens neurotrimin variant 3 p... 85 7e-16
BC050716-1|AAH50716.1| 316|Homo sapiens HNT protein protein. 85 7e-16
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 85 1e-15
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 85 1e-15
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 85 1e-15
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 85 1e-15
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 85 1e-15
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 85 1e-15
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 85 1e-15
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 85 1e-15
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 85 1e-15
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 85 1e-15
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 85 1e-15
L34774-1|AAA36387.1| 345|Homo sapiens opioid-binding cell adhes... 84 2e-15
BX537377-1|CAD97619.1| 338|Homo sapiens hypothetical protein pr... 84 2e-15
BC126251-1|AAI26252.1| 345|Homo sapiens opioid binding protein/... 84 2e-15
BC117254-1|AAI17255.1| 345|Homo sapiens opioid binding protein/... 84 2e-15
BC074773-1|AAH74773.1| 345|Homo sapiens opioid binding protein/... 84 2e-15
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 84 2e-15
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 83 3e-15
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 83 3e-15
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 83 3e-15
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 83 3e-15
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 83 3e-15
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 83 4e-15
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 83 5e-15
X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1... 83 5e-15
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 83 5e-15
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 83 5e-15
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 83 5e-15
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 83 5e-15
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 83 5e-15
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 82 7e-15
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 82 7e-15
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 82 7e-15
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 82 7e-15
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 82 7e-15
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 82 9e-15
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 82 9e-15
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 82 9e-15
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 82 9e-15
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 82 9e-15
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 82 9e-15
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 81 1e-14
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 81 1e-14
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 81 1e-14
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 81 1e-14
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 81 2e-14
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 81 2e-14
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 80 3e-14
BC074742-1|AAH74742.1| 344|Homo sapiens opioid binding protein/... 80 3e-14
AY358132-1|AAQ88499.1| 352|Homo sapiens DMML2433 protein. 80 4e-14
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 79 5e-14
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 79 5e-14
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 79 5e-14
BX538014-1|CAD97961.1| 355|Homo sapiens hypothetical protein pr... 79 5e-14
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 79 5e-14
AL645724-1|CAI21858.1| 354|Homo sapiens neuronal growth regulat... 79 5e-14
AL627317-1|CAH72391.1| 354|Homo sapiens neuronal growth regulat... 79 5e-14
AL359821-1|CAH70913.1| 354|Homo sapiens neuronal growth regulat... 79 5e-14
AL356600-1|CAI23492.1| 354|Homo sapiens neuronal growth regulat... 79 5e-14
AL354949-1|CAI16869.1| 354|Homo sapiens neuronal growth regulat... 79 5e-14
AK092307-1|BAC03858.1| 354|Homo sapiens protein ( Homo sapiens ... 79 5e-14
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 79 5e-14
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 79 6e-14
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 79 9e-14
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 78 1e-13
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 78 1e-13
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 78 1e-13
AF109126-1|AAD43217.1| 398|Homo sapiens stromal cell-derived re... 77 3e-13
AF005070-1|AAB61615.1| 348|Homo sapiens neural cell adhesion mo... 77 3e-13
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 77 3e-13
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 75 8e-13
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 75 8e-13
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 75 8e-13
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 75 8e-13
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 75 8e-13
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 75 8e-13
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 75 8e-13
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 75 8e-13
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 75 8e-13
BC101801-1|AAI01802.1| 778|Homo sapiens kin of IRRE like 3 prot... 75 1e-12
BC101775-1|AAI01776.1| 778|Homo sapiens kin of IRRE like 3 (Dro... 75 1e-12
AY358743-1|AAQ89103.1| 600|Homo sapiens NEPH2 protein. 75 1e-12
AF480410-1|AAN73042.1| 778|Homo sapiens NPEH2 protein. 75 1e-12
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 75 1e-12
AB058770-1|BAB47496.1| 779|Homo sapiens KIAA1867 protein protein. 75 1e-12
X16455-1|CAA34474.1| 697|Homo sapiens pCEA80-11 protein (647 AA... 75 1e-12
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 75 1e-12
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 75 1e-12
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 75 1e-12
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 75 1e-12
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 75 1e-12
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 75 1e-12
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 75 1e-12
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 75 1e-12
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 75 1e-12
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 75 1e-12
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 74 2e-12
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 73 4e-12
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 73 4e-12
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 73 4e-12
AK223101-1|BAD96821.1| 702|Homo sapiens carcinoembryonic antige... 73 6e-12
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 72 7e-12
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 72 7e-12
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 72 7e-12
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 72 7e-12
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 72 7e-12
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 72 1e-11
M29540-1|AAA51967.1| 702|Homo sapiens CEA protein. 72 1e-11
M17303-1|AAB59513.1| 702|Homo sapiens CEA protein. 72 1e-11
M15042-1|AAA51963.1| 698|Homo sapiens CEA protein. 72 1e-11
BC034671-1|AAH34671.1| 702|Homo sapiens carcinoembryonic antige... 72 1e-11
BC036771-1|AAH36771.1| 226|Homo sapiens NEGR1 protein protein. 71 2e-11
AL627317-2|CAH72392.1| 226|Homo sapiens neuronal growth regulat... 71 2e-11
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 71 2e-11
AL359821-2|CAH70914.1| 226|Homo sapiens neuronal growth regulat... 71 2e-11
AL356600-2|CAI23493.1| 226|Homo sapiens neuronal growth regulat... 71 2e-11
AL354949-2|CAI16870.1| 226|Homo sapiens neuronal growth regulat... 71 2e-11
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 70 3e-11
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 70 3e-11
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 70 3e-11
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 70 3e-11
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 70 3e-11
AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens ... 70 3e-11
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 70 3e-11
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 70 4e-11
AB209812-1|BAD93049.1| 391|Homo sapiens stromal cell derived fa... 69 5e-11
M59262-1|AAA62835.1| 702|Homo sapiens carcinoembryonic antigen ... 69 7e-11
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 69 7e-11
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 69 9e-11
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 69 9e-11
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 69 9e-11
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 69 9e-11
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 68 1e-10
AL139010-3|CAH73883.1| 571|Homo sapiens kin of IRRE like (Droso... 68 1e-10
AK022708-1|BAB14192.1| 571|Homo sapiens protein ( Homo sapiens ... 68 1e-10
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 68 2e-10
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 68 2e-10
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 68 2e-10
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 68 2e-10
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 68 2e-10
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 68 2e-10
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 68 2e-10
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 68 2e-10
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 68 2e-10
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 68 2e-10
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 68 2e-10
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 67 2e-10
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 67 2e-10
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 67 2e-10
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 67 2e-10
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 67 3e-10
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 67 3e-10
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 67 3e-10
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 67 3e-10
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 67 3e-10
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 67 3e-10
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 67 3e-10
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 66 4e-10
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 66 4e-10
BC046109-1|AAH46109.1| 459|Homo sapiens PTK7 protein protein. 66 5e-10
AY302131-1|AAP59845.1| 593|Homo sapiens NEPH1 protein protein. 66 5e-10
AL139010-2|CAH73882.1| 593|Homo sapiens kin of IRRE like (Droso... 66 5e-10
BC117462-1|AAI17463.1| 282|Homo sapiens neuroplastin protein. 66 6e-10
BC105979-1|AAI05980.1| 282|Homo sapiens neuroplastin protein. 66 6e-10
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 66 6e-10
AF109127-1|AAD43218.1| 282|Homo sapiens stromal cell-derived re... 66 6e-10
BC109193-1|AAI09194.1| 757|Homo sapiens KIRREL protein protein. 65 1e-09
BC109192-1|AAI09193.1| 757|Homo sapiens KIRREL protein protein. 65 1e-09
AY017369-1|AAK00529.1| 605|Homo sapiens NEPH1 protein. 65 1e-09
AL139010-1|CAH73881.1| 757|Homo sapiens kin of IRRE like (Droso... 65 1e-09
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 65 1e-09
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 64 1e-09
AY358128-1|AAQ88495.1| 717|Homo sapiens IGSF9 protein. 64 3e-09
AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down synd... 64 3e-09
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 63 3e-09
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 63 3e-09
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 63 3e-09
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 63 3e-09
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 63 3e-09
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 63 3e-09
BC025268-1|AAH25268.1| 523|Homo sapiens Unknown (protein for IM... 63 5e-09
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 63 5e-09
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 63 5e-09
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 63 5e-09
AC007567-1|AAS07434.1| 383|Homo sapiens unknown protein. 63 5e-09
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 62 6e-09
AB046848-1|BAB13454.1| 980|Homo sapiens KIAA1628 protein protein. 62 8e-09
X59350-1|CAA42006.1| 847|Homo sapiens B Cell membrane protein C... 62 1e-08
U62631-1|AAB06448.1| 847|Homo sapiens B-cell receptor CD22-B is... 62 1e-08
EF064756-1|ABK41939.1| 847|Homo sapiens CD22 molecule protein. 62 1e-08
AB253795-1|BAF32758.1| 847|Homo sapiens CD22 antigen protein. 62 1e-08
AB253794-1|BAF32757.1| 847|Homo sapiens CD22 antigen protein. 62 1e-08
AB253793-1|BAF32756.1| 847|Homo sapiens CD22 antigen protein. 62 1e-08
S61375-1|AAC18956.1| 662|Homo sapiens CD22 protein protein. 61 1e-08
BC109306-1|AAI09307.1| 675|Homo sapiens CD22 protein protein. 61 1e-08
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 61 1e-08
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 61 1e-08
AY358742-1|AAQ89102.1| 708|Homo sapiens LRMR5827 protein. 61 1e-08
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 61 1e-08
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 61 1e-08
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 61 1e-08
X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein. 61 2e-08
M18728-1|AAA59907.1| 344|Homo sapiens non-specific cross reacti... 61 2e-08
BT009774-1|AAP88776.1| 344|Homo sapiens carcinoembryonic antige... 61 2e-08
BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein. 61 2e-08
BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein ... 61 2e-08
BC005008-1|AAH05008.1| 344|Homo sapiens carcinoembryonic antige... 61 2e-08
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 61 2e-08
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 61 2e-08
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein. 60 3e-08
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 60 3e-08
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 60 3e-08
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 60 3e-08
AY305302-1|AAP72167.1| 583|Homo sapiens kin of irregular chiasm... 60 3e-08
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 60 4e-08
M29541-1|AAA59915.1| 344|Homo sapiens normal cross-reacting ant... 60 4e-08
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ... 60 4e-08
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 60 4e-08
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 60 4e-08
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 60 4e-08
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 60 4e-08
M18216-1|AAA51739.1| 344|Homo sapiens NCA protein. 59 6e-08
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 59 6e-08
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 59 6e-08
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 59 6e-08
BC141884-1|AAI41885.1| 1688|Homo sapiens SIGLEC1 protein protein. 59 7e-08
AL109804-4|CAC17543.1| 1709|Homo sapiens sialic acid binding Ig-... 59 7e-08
AF230073-1|AAK00757.1| 1709|Homo sapiens sialoadhesin protein. 59 7e-08
AY305301-1|AAP72166.1| 633|Homo sapiens kin of irregular chiasm... 58 1e-07
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 58 1e-07
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 58 1e-07
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 58 1e-07
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 58 2e-07
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 58 2e-07
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 57 2e-07
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 57 2e-07
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 57 2e-07
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 57 2e-07
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 57 2e-07
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 57 2e-07
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 57 2e-07
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 57 2e-07
CR533512-1|CAG38543.1| 299|Homo sapiens F11R protein. 57 3e-07
BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein pr... 57 3e-07
BT020103-1|AAV38906.1| 299|Homo sapiens F11 receptor protein. 57 3e-07
BC001533-1|AAH01533.1| 299|Homo sapiens F11 receptor protein. 57 3e-07
AY358896-1|AAQ89255.1| 299|Homo sapiens JAM protein. 57 3e-07
AL591806-2|CAI15365.1| 299|Homo sapiens F11 receptor protein. 57 3e-07
AK075152-1|BAC11436.1| 299|Homo sapiens protein ( Homo sapiens ... 57 3e-07
AF490407-1|AAO84556.1| 299|Homo sapiens JAM1 protein. 57 3e-07
AF207907-1|AAF22829.1| 299|Homo sapiens platelet F11 receptor p... 57 3e-07
AF191495-1|AAG28379.1| 299|Homo sapiens F11 receptor protein pr... 57 3e-07
AF172398-1|AAD48877.1| 299|Homo sapiens junctional adhesion mol... 57 3e-07
AF111713-1|AAD42050.1| 299|Homo sapiens junctional adhesion mol... 57 3e-07
AF154005-1|AAD43794.1| 259|Homo sapiens junction adhesion molec... 56 4e-07
AF035287-1|AAB88179.1| 154|Homo sapiens protein ( Homo sapiens ... 56 4e-07
X64699-1|CAA45940.1| 531|Homo sapiens titin protein. 56 5e-07
X64698-1|CAA45939.1| 1100|Homo sapiens titin protein. 56 5e-07
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 56 5e-07
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 56 7e-07
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 56 7e-07
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 56 7e-07
M16234-1|AAA51972.1| 372|Homo sapiens CEA protein. 56 7e-07
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 56 7e-07
BC112138-1|AAI12139.1| 435|Homo sapiens CADM2 protein protein. 56 7e-07
BC112136-1|AAI12137.1| 435|Homo sapiens CADM2 protein protein. 56 7e-07
BC105999-1|AAI06000.1| 404|Homo sapiens CADM2 protein protein. 56 7e-07
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 56 7e-07
AF538973-1|AAN16368.1| 437|Homo sapiens nectin-like protein 3 p... 56 7e-07
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 56 7e-07
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 56 7e-07
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 56 7e-07
X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein. 55 9e-07
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 55 9e-07
BC017779-1|AAH17779.1| 298|Homo sapiens junctional adhesion mol... 54 2e-06
AY358361-1|AAQ88727.1| 312|Homo sapiens JAM-IT/VE-JAM protein. 54 2e-06
AY077698-1|AAL82538.1| 298|Homo sapiens C21ORF43 protein. 54 2e-06
AY016009-1|AAG49022.1| 298|Homo sapiens junctional adhesion mol... 54 2e-06
AF478693-1|AAM77220.1| 955|Homo sapiens glycosyl-phosphatidyl-i... 54 2e-06
AF255910-1|AAF81223.1| 298|Homo sapiens vascular endothelial ju... 54 2e-06
M22734-1|AAA60048.1| 1089|Homo sapiens platelet-derived growth f... 54 2e-06
M21574-1|AAA96715.1| 1089|Homo sapiens platelet-derived growth f... 54 2e-06
D50017-1|BAA08742.1| 1089|Homo sapiens alpha-platelet-derived gr... 54 2e-06
BC063414-1|AAH63414.1| 743|Homo sapiens PDGFRA protein protein. 54 2e-06
AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein. 54 2e-06
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 54 3e-06
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 53 4e-06
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 53 4e-06
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 53 4e-06
M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth fa... 53 5e-06
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 53 5e-06
BC024300-1|AAH24300.1| 605|Homo sapiens FSTL4 protein protein. 53 5e-06
AB028984-1|BAA83013.1| 693|Homo sapiens KIAA1061 protein protein. 53 5e-06
L05606-1|AAA36339.1| 476|Homo sapiens protein ( Human myosin bi... 52 6e-06
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 52 6e-06
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr... 52 8e-06
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 52 1e-05
AY358330-1|AAQ88696.1| 477|Homo sapiens papilin protein. 52 1e-05
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 51 1e-05
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 51 1e-05
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 51 1e-05
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 51 1e-05
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 51 1e-05
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 51 1e-05
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 51 1e-05
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 51 1e-05
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 51 1e-05
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 51 1e-05
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 51 1e-05
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 51 1e-05
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 51 1e-05
AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein. 51 1e-05
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr... 51 1e-05
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 51 1e-05
X64116-3|CAA45480.1| 364|Homo sapiens poliovirus receptor gamma... 51 2e-05
X64116-2|CAA45479.1| 372|Homo sapiens poliovirus receptor beta ... 51 2e-05
X64116-1|CAA45478.1| 417|Homo sapiens poliovirus receptor alpha... 51 2e-05
M24407-1|AAA36461.1| 417|Homo sapiens protein ( Human polioviru... 51 2e-05
M24406-1|AAA36462.1| 392|Homo sapiens protein ( Human polioviru... 51 2e-05
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 51 2e-05
BC015542-1|AAH15542.1| 417|Homo sapiens poliovirus receptor pro... 51 2e-05
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 51 2e-05
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 51 2e-05
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 51 2e-05
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 51 2e-05
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 51 2e-05
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 51 2e-05
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 51 2e-05
AC068948-1|AAF69803.1| 417|Homo sapiens poliovirus receptor pro... 51 2e-05
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 50 3e-05
U11814-1|AAA68514.1| 366|Homo sapiens soluble keratinocyte grow... 50 3e-05
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 50 3e-05
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 50 3e-05
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 50 3e-05
>AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein.
Length = 1241
Score = 223 bits (545), Expect = 2e-57
Identities = 147/484 (30%), Positives = 234/484 (48%), Gaps = 17/484 (3%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+E ++ V NP + WT G ++ + RI+S G+ L++ +TR D G
Sbjct: 659 VEQGEALLPVSVSANPAPEAFNWTFRGYRLSPAG--GPRHRILSSGA-LHLWNVTRADDG 715
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y NS+G A A + + VHY I+++ N + CT NP+L W
Sbjct: 716 LYQLHCQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTVDANPILPGMFNW 775
Query: 297 ERKGYKIDPKSVTFEPK---NLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
ER G + +S+ K T L I AK G +QC+V+NG+ ++ + L+V+
Sbjct: 776 ERLGEDEEDQSLDDMEKISRGPTGRLRIHHAKLAQAGAYQCIVDNGVAPPARRLLRLVVR 835
Query: 354 FKPEMD--TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
F P+++ T V +A + L C+ + VP FTW+KNGV P++ + E
Sbjct: 836 FAPQVEHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFTWTKNGV--PLDLQDPRYTEHT 893
Query: 412 KNDHITYTSVLLINNV-ATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
+ ++S+L I NV A DY + C A N LG T ++L S PD L V ++T
Sbjct: 894 YHQGGVHSSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVSISRPDPPSGLKVVSLT 953
Query: 471 HSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSV 530
+V LEW PGFDGGL + IRY + + Y DV+P AT FT+ GL+ +T Y +
Sbjct: 954 PHSVGLEWKPGFDGGLPQRFCIRYEALGTPGFHYVDVVPPQATTFTLTGLQPSTRYRVWL 1013
Query: 531 MAINKIGQSKYRPDDTKATTLT---SSEVGE-LSTVSTEYVETPDISKPVIVYVSLTGAV 586
+A N +G S T+ T GE + TE P P++ + G +
Sbjct: 1014 LASNALGDSGLADKGTQLPITTPGLHQPSGEPEDQLPTEPPSGPS-GLPLLPVLFALGGL 1072
Query: 587 LVLINVALIACFVWKRRLRRIKEQAGQASKSATIEMYAPSSYNDTM-TGETLSSVSEKSE 645
L+L N + + +W+RRLRR+ E + +++ + E + Y ++ TGE + S S
Sbjct: 1073 LLLSNASCVGGVLWQRRLRRLAEGISEKTEAGSEEDRVRNEYEESQWTGERDTQSSTVST 1132
Query: 646 TYSQ 649
T ++
Sbjct: 1133 TEAE 1136
Score = 80.6 bits (190), Expect = 2e-14
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 19/160 (11%)
Query: 11 KCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDK------- 63
K +I + P I G G L AGT +L C++ GGNP +L W+K+ +
Sbjct: 431 KSLILNVKYPAQKLWIEGPPEGQKLRAGTRVRLVCLAIGGNPEPSLMWYKDSRTVTESRL 490
Query: 64 -----KIH-STTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFA 117
++H + + + S E+ ++T +DNQA++ C+A L + L V F
Sbjct: 491 PQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKAGQ------LSASTQLAVQFP 544
Query: 118 PEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
P V + A L+PG L C S SSNPP LSW ++G
Sbjct: 545 PTNVTILANASALRPGDALNLTCVSVSSNPPVNLSWDKEG 584
Score = 75.8 bits (178), Expect = 6e-13
Identities = 49/140 (35%), Positives = 68/140 (48%), Gaps = 8/140 (5%)
Query: 20 PPSAPMITGYVPGTT---LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT-DKA 75
PP P+I PG + AG +L C++ GGNPLATL W KN + + + T +A
Sbjct: 239 PPGPPVIEW--PGLDEGHVRAGQSLELPCVARGGNPLATLQWLKNGQPVSTAWGTEHTQA 296
Query: 76 VSAEISILT-NVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
V+ + ++T D+ AQ CEA NS + +TL V F P A+ + +
Sbjct: 297 VARSVLVMTVRPEDHGAQLSCEAHNSVSAGTQEHGITLQVTFPPSAIIILGSASQTE-NK 355
Query: 135 EATLICDSASSNPPATLSWW 154
TL C S SS P L WW
Sbjct: 356 NVTLSCVSKSSRPRVLLRWW 375
Score = 50.4 bits (115), Expect = 3e-05
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 13/156 (8%)
Query: 20 PPSAPMITGYVPGT--TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKA-- 75
PP ++T GT T AG + C+S P +T + + I + ++
Sbjct: 134 PPKLLLLTPEA-GTMVTWVAGQEYVVNCVSGDAKPAPDITILLSGQTISDISANVNEGSQ 192
Query: 76 -----VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVR---AEP 127
V A + +DN+ CEA++ A E P+ + T+NV F P + +
Sbjct: 193 QKLFTVEATARVTPRSSDNRQLLVCEASSPALEAPIKASFTVNVLFPPGPPVIEWPGLDE 252
Query: 128 DVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
++ G L C + NP ATL W ++G PV A
Sbjct: 253 GHVRAGQSLELPCVARGGNPLATLQWLKNGQPVSTA 288
Score = 49.2 bits (112), Expect = 6e-05
Identities = 39/168 (23%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAE 79
PPSA +I G T T L+C+S P L W+ +++ +T +
Sbjct: 339 PPSAIIILGSASQTENKNVT---LSCVSKSSRPRVLLRWWLGWRQLLPMEETVMDGLHGG 395
Query: 80 ISILTNVT------DNQAQYRCEATNSA-TEIPLFETVTLNVHFAPEAVKVRAEPD--VL 130
++N+T DN CEA + A T+ +++ LNV + + + + P+ L
Sbjct: 396 HISMSNLTFLARREDNGLTLTCEAFSEAFTKETFKKSLILNVKYPAQKLWIEGPPEGQKL 455
Query: 131 KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIE 178
+ G L+C + NP +L W++D V + + ++ + +E
Sbjct: 456 RAGTRVRLVCLAIGGNPEPSLMWYKDSRTVTESRLPQESRRVHLGSVE 503
Score = 37.5 bits (83), Expect = 0.19
Identities = 33/137 (24%), Positives = 57/137 (41%), Gaps = 12/137 (8%)
Query: 26 ITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT----KTTDKAVSAEIS 81
+T + L G L C+S NP L+W K +++ + K +A S
Sbjct: 548 VTILANASALRPGDALNLTCVSVSSNPPVNLSWDKEGERLEGVAAPPRRAPFKGSAAARS 607
Query: 82 ILTNVT--DNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIE--AT 137
+L V+ D+ + C A ++ + LNV + PE + E ++ +E
Sbjct: 608 VLLQVSSRDHGQRVTCRAHSAELRETVSSFYRLNVLYRPEFL---GEQVLVVTAVEQGEA 664
Query: 138 LICDSASSNP-PATLSW 153
L+ S S+NP P +W
Sbjct: 665 LLPVSVSANPAPEAFNW 681
Score = 36.7 bits (81), Expect = 0.34
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 188 ADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
A G P T W K+G P++ +++ + + + ++ S+L MT +CEA NS
Sbjct: 267 ARGGNPLATLQWLKNGQPVS-TAWGTEHTQAVAR-SVLVMTVRPEDHGAQLSCEAHNSVS 324
Query: 248 AAVA--NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTA 284
A I++ V +P + + N++ LSC +
Sbjct: 325 AGTQEHGITLQVTFPPSAIIILGSASQTENKNVTLSCVS 363
>AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein.
Length = 1241
Score = 223 bits (545), Expect = 2e-57
Identities = 147/484 (30%), Positives = 234/484 (48%), Gaps = 17/484 (3%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+E ++ V NP + WT G ++ + RI+S G+ L++ +TR D G
Sbjct: 659 VEQGEALLPVSVSANPAPEAFNWTFRGYRLSPAG--GPRHRILSSGA-LHLWNVTRADDG 715
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y NS+G A A + + VHY I+++ N + CT NP+L W
Sbjct: 716 LYQLHCQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTVDANPILPGMFNW 775
Query: 297 ERKGYKIDPKSVTFEPK---NLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
ER G + +S+ K T L I AK G +QC+V+NG+ ++ + L+V+
Sbjct: 776 ERLGEDEEDQSLDDMEKISRGPTGRLRIHHAKLAQAGAYQCIVDNGVAPPARRLLRLVVR 835
Query: 354 FKPEMD--TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
F P+++ T V +A + L C+ + VP FTW+KNGV P++ + E
Sbjct: 836 FAPQVEHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFTWTKNGV--PLDLQDPRYTEHT 893
Query: 412 KNDHITYTSVLLINNV-ATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
+ ++S+L I NV A DY + C A N LG T ++L S PD L V ++T
Sbjct: 894 YHQGGVHSSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVSISRPDPPSGLKVVSLT 953
Query: 471 HSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSV 530
+V LEW PGFDGGL + IRY + + Y DV+P AT FT+ GL+ +T Y +
Sbjct: 954 PHSVGLEWKPGFDGGLPQRFCIRYEALGTPGFHYVDVVPPQATTFTLTGLQPSTRYRVWL 1013
Query: 531 MAINKIGQSKYRPDDTKATTLT---SSEVGE-LSTVSTEYVETPDISKPVIVYVSLTGAV 586
+A N +G S T+ T GE + TE P P++ + G +
Sbjct: 1014 LASNALGDSGLADKGTQLPITTPGLHQPSGEPEDQLPTEPPSGPS-GLPLLPVLFALGGL 1072
Query: 587 LVLINVALIACFVWKRRLRRIKEQAGQASKSATIEMYAPSSYNDTM-TGETLSSVSEKSE 645
L+L N + + +W+RRLRR+ E + +++ + E + Y ++ TGE + S S
Sbjct: 1073 LLLSNASCVGGVLWQRRLRRLAEGISEKTEAGSEEDRVRNEYEESQWTGERDTQSSTVST 1132
Query: 646 TYSQ 649
T ++
Sbjct: 1133 TEAE 1136
Score = 80.6 bits (190), Expect = 2e-14
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 19/160 (11%)
Query: 11 KCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDK------- 63
K +I + P I G G L AGT +L C++ GGNP +L W+K+ +
Sbjct: 431 KSLILNVKYPAQKLWIEGPPEGQKLRAGTRVRLVCLAIGGNPEPSLMWYKDSRTVTESRL 490
Query: 64 -----KIH-STTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFA 117
++H + + + S E+ ++T +DNQA++ C+A L + L V F
Sbjct: 491 PQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKAGQ------LSASTQLAVQFP 544
Query: 118 PEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
P V + A L+PG L C S SSNPP LSW ++G
Sbjct: 545 PTNVTILANASALRPGDALNLTCVSVSSNPPVNLSWDKEG 584
Score = 75.8 bits (178), Expect = 6e-13
Identities = 49/140 (35%), Positives = 68/140 (48%), Gaps = 8/140 (5%)
Query: 20 PPSAPMITGYVPGTT---LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT-DKA 75
PP P+I PG + AG +L C++ GGNPLATL W KN + + + T +A
Sbjct: 239 PPGPPVIEW--PGLDEGHVRAGQSLELPCVARGGNPLATLQWLKNGQPVSTAWGTEHTQA 296
Query: 76 VSAEISILT-NVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
V+ + ++T D+ AQ CEA NS + +TL V F P A+ + +
Sbjct: 297 VARSVLVMTVRPEDHGAQLSCEAHNSVSAGTQEHGITLQVTFPPSAIIILGSASQTE-NK 355
Query: 135 EATLICDSASSNPPATLSWW 154
TL C S SS P L WW
Sbjct: 356 NVTLSCVSKSSRPRVLLRWW 375
Score = 50.4 bits (115), Expect = 3e-05
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 13/156 (8%)
Query: 20 PPSAPMITGYVPGT--TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKA-- 75
PP ++T GT T AG + C+S P +T + + I + ++
Sbjct: 134 PPKLLLLTPEA-GTMVTWVAGQEYVVNCVSGDAKPAPDITILLSGQTISDISANVNEGSQ 192
Query: 76 -----VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVR---AEP 127
V A + +DN+ CEA++ A E P+ + T+NV F P + +
Sbjct: 193 QKLFTVEATARVTPRSSDNRQLLVCEASSPALEAPIKASFTVNVLFPPGPPVIEWPGLDE 252
Query: 128 DVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
++ G L C + NP ATL W ++G PV A
Sbjct: 253 GHVRAGQSLELPCVARGGNPLATLQWLKNGQPVSTA 288
Score = 49.2 bits (112), Expect = 6e-05
Identities = 39/168 (23%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAE 79
PPSA +I G T T L+C+S P L W+ +++ +T +
Sbjct: 339 PPSAIIILGSASQTENKNVT---LSCVSKSSRPRVLLRWWLGWRQLLPMEETVMDGLHGG 395
Query: 80 ISILTNVT------DNQAQYRCEATNSA-TEIPLFETVTLNVHFAPEAVKVRAEPD--VL 130
++N+T DN CEA + A T+ +++ LNV + + + + P+ L
Sbjct: 396 HISMSNLTFLARREDNGLTLTCEAFSEAFTKETFKKSLILNVKYPAQKLWIEGPPEGQKL 455
Query: 131 KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIE 178
+ G L+C + NP +L W++D V + + ++ + +E
Sbjct: 456 RAGTRVRLVCLAIGGNPEPSLMWYKDSRTVTESRLPQESRRVHLGSVE 503
Score = 37.5 bits (83), Expect = 0.19
Identities = 33/137 (24%), Positives = 57/137 (41%), Gaps = 12/137 (8%)
Query: 26 ITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT----KTTDKAVSAEIS 81
+T + L G L C+S NP L+W K +++ + K +A S
Sbjct: 548 VTILANASALRPGDALNLTCVSVSSNPPVNLSWDKEGERLEGVAAPPRRAPFKGSAAARS 607
Query: 82 ILTNVT--DNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIE--AT 137
+L V+ D+ + C A ++ + LNV + PE + E ++ +E
Sbjct: 608 VLLQVSSRDHGQRVTCRAHSAELRETVSSFYRLNVLYRPEFL---GEQVLVVTAVEQGEA 664
Query: 138 LICDSASSNP-PATLSW 153
L+ S S+NP P +W
Sbjct: 665 LLPVSVSANPAPEAFNW 681
Score = 36.7 bits (81), Expect = 0.34
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 188 ADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
A G P T W K+G P++ +++ + + + ++ S+L MT +CEA NS
Sbjct: 267 ARGGNPLATLQWLKNGQPVS-TAWGTEHTQAVAR-SVLVMTVRPEDHGAQLSCEAHNSVS 324
Query: 248 AAVA--NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTA 284
A I++ V +P + + N++ LSC +
Sbjct: 325 AGTQEHGITLQVTFPPSAIIILGSASQTENKNVTLSCVS 363
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 124 bits (299), Expect = 1e-27
Identities = 111/376 (29%), Positives = 165/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 1028 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 1087
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 1088 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 1143
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L +T + DAG YTC A N G++
Sbjct: 1144 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQITFVQPGDAGHYTCMAANVAGSSST 1197
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 1198 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 1255
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 1256 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 1309
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 1310 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 1358
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 1359 EDSGTYVCTAENSVGF 1374
Score = 95.1 bits (226), Expect = 9e-19
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 901 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 957
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 958 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 1011
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 1012 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 1069
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 1070 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 1125
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 1126 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQITF 1175
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 1176 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 1207
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 100 DSESLSVVNVR-EGTSVSLEXESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 153
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 154 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 213
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 214 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 270
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 271 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 327
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 328 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 378
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 672 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 726
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 727 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 784
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 785 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 842
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 843 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 893
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 894 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 953
Query: 474 VT 475
+T
Sbjct: 954 IT 955
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 585 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 643
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 644 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 700
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 701 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 760
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 761 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 820
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 821 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 878
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 879 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 937
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 938 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 986
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 987 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 1026
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 204 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 260
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 261 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 318
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 319 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 378
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 379 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 432
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 433 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 484
Score = 75.4 bits (177), Expect = 8e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 1311 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 1362
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANP-NEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K + P +A+L+C G+P I+
Sbjct: 1363 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSHWIEPLGGNAILNCEVKGDP--TPTIQ 1420
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 1421 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 1476
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 1477 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 1524
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 1525 NVLSNNSLYIADAQKEDTSEFECVARNLMG 1554
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 300 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 354
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 355 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 412
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 413 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 470
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 471 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 522
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 523 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 565
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 498 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 551
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 552 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 606
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 607 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 664
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 665 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 713
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 714 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 752
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 9 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 63
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 64 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNA 123
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 124 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 181
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 182 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 240
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 241 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 269
Score = 59.7 bits (138), Expect = 4e-08
Identities = 50/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F + + I++ G+P T W + G+ I S R +
Sbjct: 1383 VKEPPVFKGDYPSHWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 1437
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 1438 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 1496
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 1497 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 1552
Query: 340 IGS 342
+GS
Sbjct: 1553 MGS 1555
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 283 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 341
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 342 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 399
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 400 IECRATGTPPPQINWLKNGLPL 421
Score = 44.8 bits (101), Expect = 0.001
Identities = 43/170 (25%), Positives = 70/170 (41%), Gaps = 15/170 (8%)
Query: 6 DSGIFKCM-INSPSDPPSAPMITGYVPGT-------TLAAGTVQKLACIS----TGGNPL 53
D G + C+ IN + +T YVP + +L+ V++ +S + P
Sbjct: 67 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPP 126
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW+KN + I +T A + I + QY C A N A + LN
Sbjct: 127 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD--KNFHLN 184
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
V+ P E V TL CD A+ PP T++W ++ ++N+
Sbjct: 185 VYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNHKRIENS 233
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 484 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 542
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 543 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 599
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 600 WMKDGRPL 607
Score = 40.7 bits (91), Expect = 0.021
Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 13 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 71
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI-EATLICDSASSN--PPAT 150
C A N A E ++T+ + P ++K + + E T + SN PP
Sbjct: 72 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPV 128
Query: 151 LSWWRDG 157
++W+++G
Sbjct: 129 ITWYKNG 135
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 1413 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 1471
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 1472 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 1515
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 1045 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 1103
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 1104 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 1154
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 842 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 900
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 901 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 955
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 956 CTASGVPFPSIHWTKNGI 973
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 630 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 688
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 689 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 748
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 749 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 788
Score = 33.9 bits (74), Expect = 2.4
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 78 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLEXESNAVPP-PVITWYKNG 135
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 136 RMITESTHVEILAD 149
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 123 bits (297), Expect = 2e-27
Identities = 113/389 (29%), Positives = 168/389 (43%), Gaps = 35/389 (8%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3991 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4050
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4051 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4106
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4107 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4160
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4161 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4218
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4219 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4272
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4273 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4321
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAP 458
D G+Y C A N +GF T + V P
Sbjct: 4322 EDSGTYVCTAENSVGFVKATGFVYVKEPP 4350
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNCLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSTQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 96.7 bits (230), Expect = 3e-19
Identities = 83/296 (28%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3063 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3116
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3117 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3176
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K YK S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3177 TGIP--PPTIAW-LKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3233
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3234 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3290
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3291 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3341
Score = 95.1 bits (226), Expect = 9e-19
Identities = 82/302 (27%), Positives = 129/302 (42%), Gaps = 17/302 (5%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V AP + + V + N P+ + A G P PS+T W KDG P+ SS+S+G
Sbjct: 2006 LQVHVAPSISGSNNMVAV-VVNNPVRLECEARGIPAPSLT--WLKDGSPV--SSFSNGL- 2059
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
+++S G +L +T D G YTC AVN+ G +I + V+ P I QNV ++
Sbjct: 2060 QVLSGGRILALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQ 2119
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
L C + P + W + G+ + K +N S L I A+ ++ G + C
Sbjct: 2120 AVELLCQSDAIP--PPTLTWLKDGHPLLKKPGLSISEN-RSVLKIEDAQVQDTGRYTCEA 2176
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K++ + + P + S + G + L+C+ +P P+ W K G
Sbjct: 2177 TNVAGKTEKKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKG- 2235
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
PV T + ++ L I+ SD Y C A N G + L V
Sbjct: 2236 -SPVLTDSMGRVRI-----LSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYI 2289
Query: 457 AP 458
P
Sbjct: 2290 RP 2291
Score = 94.7 bits (225), Expect = 1e-18
Identities = 74/304 (24%), Positives = 127/304 (41%), Gaps = 20/304 (6%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGND 216
+ V P+ D + V + N+ + +G P I W KD + +T+SS
Sbjct: 1353 LKVHVPPVIKDKEQVSNVSVLLNQLTNLFCEVEGTPSPIIM-WYKDNVQVTESS----TI 1407
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVS--QNVVANP 274
+ ++ G +L + + T DAG Y+C+A+N G + ++ V P I + + V
Sbjct: 1408 QTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPKEVSVVL 1467
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N D L C G P I W + G + E + L ++ A+ + G +QC
Sbjct: 1468 NRDVALECQVKGTPF--PDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQC 1525
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKN 394
V+N G K D+ L + P + + + + +L CK + +P P+ TW K+
Sbjct: 1526 TVSNAAGKQAK-DIKLTIYIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPAITWYKD 1584
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
G P+ +S++ +I L I SD +Y C N G + + +DV
Sbjct: 1585 G--QPIMSSSQAL-------YIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Query: 455 TSAP 458
P
Sbjct: 1636 YVPP 1639
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3864 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3920
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3921 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3974
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3975 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4032
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4033 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4088
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4089 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4138
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4139 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4170
Score = 93.9 bits (223), Expect = 2e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3635 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3689
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3690 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3747
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3748 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3805
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3806 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3856
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3857 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3916
Query: 474 VT 475
+T
Sbjct: 3917 IT 3918
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3548 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3606
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3607 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3663
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3664 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3723
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3724 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3783
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3784 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3841
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3842 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3900
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3901 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3949
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3950 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3989
Score = 88.6 bits (210), Expect = 8e-17
Identities = 75/286 (26%), Positives = 117/286 (40%), Gaps = 20/286 (6%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNCLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + + + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSTQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
K +N SVL I + D G Y C A N G
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 85.8 bits (203), Expect = 6e-16
Identities = 91/343 (26%), Positives = 134/343 (39%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ EG++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEEGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVSNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF K S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPKEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPAITWYK 1583
Score = 84.6 bits (200), Expect = 1e-15
Identities = 83/302 (27%), Positives = 119/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F L + + E G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFS-AGADGSLYVVSPEGEESGEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDLRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 84.6 bits (200), Expect = 1e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2888 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2942
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2943 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 3000
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3001 KNXQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINXAGE-SKKKFSLTVYVPPS 3058
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3059 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3112
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3113 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3169
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3170 VTLTCDATGIP 3180
Score = 80.2 bits (189), Expect = 3e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSM--LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + L++ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVSLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 78.6 bits (185), Expect = 9e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3167 SNPVTLTCDATGIPPP-TIAWLKNYKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3223
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3224 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3281
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3282 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3341
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3342 TIRGNKDEAEKLMTYVDTSINIECRXTGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3395
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3396 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3447
Score = 78.2 bits (184), Expect = 1e-13
Identities = 87/317 (27%), Positives = 126/317 (39%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECNAAGNPSPIL-TWLKDGVPVK----ANDNFRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 78.2 bits (184), Expect = 1e-13
Identities = 81/302 (26%), Positives = 118/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2291 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2345
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2346 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2405
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2406 SLTCEASGIPL--PSTTWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2460
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2461 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2519
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2520 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2570
Query: 457 AP 458
+P
Sbjct: 2571 SP 2572
Score = 77.8 bits (183), Expect = 1e-13
Identities = 72/275 (26%), Positives = 115/275 (41%), Gaps = 27/275 (9%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+E + ++ A G P T TW KDG P++ S+ + RI+S G ML + + T DAG
Sbjct: 2400 VEKNSVSLTCEASGIPLPST-TWFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDAG 2454
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC N+ G +SV P I ++ ++V + L+C GNP+ I
Sbjct: 2455 QYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PEI 2512
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2513 TWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVFV 2570
Query: 355 KPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2571 SPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI--- 2625
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2626 ------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2654
Score = 77.8 bits (183), Expect = 1e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4274 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4325
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4326 TYVCTAENSVGFVKATGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4383
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4384 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4439
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4440 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4487
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4488 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4517
Score = 73.7 bits (173), Expect = 2e-12
Identities = 76/284 (26%), Positives = 112/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3263 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3317
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C G P I
Sbjct: 3318 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTYVDTSINIECRXTGTP--PPQI 3375
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3376 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3433
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3434 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3485
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3486 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3528
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3461 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3514
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3515 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3569
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3570 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3627
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3628 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3676
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3677 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3715
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2575 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2629
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2630 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2689
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2690 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2745
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2746 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2804
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2805 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2855
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2856 GEDSLQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2915
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2916 EDDHHKF 2922
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/286 (25%), Positives = 113/286 (39%), Gaps = 26/286 (9%)
Query: 179 NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
N + + + G P P I W KDG P+ N ++ G +L++ R+D G
Sbjct: 1468 NRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPNVELLDRGQVLHLKNARRNDKGR 1522
Query: 238 YTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C N+ G +I ++++ P IK +V+ ++ N L C G P+ A I
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPA--IT 1580
Query: 296 WERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ---DVMLIV 352
W + G I S YL I +A+ + + C V N G+A K DV +
Sbjct: 1581 WYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPP 1639
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ + T N + L C P+P TW K+GV + N + + A K
Sbjct: 1640 MIEGNLATPLN---KQVVIAHSLTLECNAAGNPSPILTWLKDGVPVKANDNFRIEAGGKK 1696
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
L I + D G Y C A + G ++DV P
Sbjct: 1697 ---------LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPP 1733
Score = 69.3 bits (162), Expect = 5e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2210 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2266
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2267 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2324
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2325 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2382
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2383 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRI------ 2436
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2437 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2490
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2972 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNXQPIKLNT----NTLIVPGGRTLQIIRA 3026
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3027 KVSDGGEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3086
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3087 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3144
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3145 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRI 3203
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3204 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3232
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 67.3 bits (157), Expect = 2e-10
Identities = 76/299 (25%), Positives = 114/299 (38%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L E
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILE-- 1318
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++L+I +V D G Y C A NE G + L V P V+NV+
Sbjct: 1319 ------EGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVSNVS 1371
Score = 63.7 bits (148), Expect = 3e-09
Identities = 78/314 (24%), Positives = 125/314 (39%), Gaps = 30/314 (9%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2703 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2758
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2759 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2818
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVKFKPEMDT 360
+ V P L I +AK E+ G + CV N G + Q DV ++V E
Sbjct: 2819 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIEGAN 2876
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
S + V + + C PAP +W K+G L + + HK ++
Sbjct: 2877 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSNGR 2927
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTLEW 478
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2928 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC 2987
Query: 479 -VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2988 EVSGFPPPDLSWLK 3001
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4346 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4400
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4401 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4459
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4460 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4515
Query: 340 IGS 342
+GS
Sbjct: 4516 MGS 4518
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSTQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.8 bits (121), Expect = 5e-06
Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2604 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2661
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2662 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2718
Score = 46.4 bits (105), Expect = 4e-04
Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3246 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3304
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3305 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTYVDTSIN 3362
Query: 140 CD-SASSNPPATLSWWRDGIPV 160
+ + PP ++W ++G+P+
Sbjct: 3363 IECRXTGTPPPQINWLKNGLPL 3384
Score = 46.0 bits (104), Expect = 6e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3075 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3133
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3134 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNY 3190
Query: 158 IPVQNA 163
++N+
Sbjct: 3191 KRIENS 3196
Score = 45.2 bits (102), Expect = 0.001
Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL + TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2407 LTC-EASGIPLPSTTWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2465
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2466 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2522
Score = 44.8 bits (101), Expect = 0.001
Identities = 38/170 (22%), Positives = 78/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-KTRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + +A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECNAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2500 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2558
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2559 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2615
Query: 159 PVQN 162
P+++
Sbjct: 2616 PLES 2619
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.9 bits (94), Expect = 0.009
Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN + I T T + I+ + +Y
Sbjct: 2976 TVVVNNFISLTC-EVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3034
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3035 TCIAINXAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3090
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3091 VITWYKNG 3098
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C + GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-NAAGNPSPILTWLKDGVPVKANDNFRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3447 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3505
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3506 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3562
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3563 WMKDGRPL 3570
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4376 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4434
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4435 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4478
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4008 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4066
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4067 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4117
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2703 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2760
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2761 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2819
Query: 161 QNA 163
++
Sbjct: 2820 TSS 2822
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3805 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3863
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3864 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3918
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3919 CTASGVPFPSIHWTKNGI 3936
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 38.3 bits (85), Expect = 0.11
Identities = 30/113 (26%), Positives = 46/113 (40%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2802 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2861
Query: 108 ETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPV 160
V + V E +V ++ LI +S +P SW +DG P+
Sbjct: 2862 YDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2914
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3593 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3651
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3652 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3711
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3712 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3751
Score = 35.9 bits (79), Expect = 0.60
Identities = 25/115 (21%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C + PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECKTRGLPMPA-ITWYKDGQPIMSS 1591
Score = 34.3 bits (75), Expect = 1.8
Identities = 29/121 (23%), Positives = 48/121 (39%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPEGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDLRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 122 bits (294), Expect = 5e-27
Identities = 110/376 (29%), Positives = 164/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4049
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4050 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4105
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4106 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4160 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4217
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4218 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4271
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4272 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4320
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 4321 EDSGTYVCTAENSVGF 4336
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3062 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3115
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3176 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3233 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3289
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3290 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3919
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3920 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3973
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4031
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4032 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4087
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4137
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3634 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3688
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3746
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3747 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3804
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3805 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3855
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 474 VT 475
+T
Sbjct: 3916 IT 3917
Score = 93.1 bits (221), Expect = 4e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 91.9 bits (218), Expect = 9e-18
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 25/313 (7%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
K +N SVL I + D G Y C A N G + +++ P
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 459 -----DQVVSLTV 466
D++ LTV
Sbjct: 2196 NIGGSDELTQLTV 2208
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3547 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3606 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3662
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3722
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3840
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3899
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3900 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3948
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3949 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 83.8 bits (198), Expect = 2e-15
Identities = 83/302 (27%), Positives = 120/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2887 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2941
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 2999
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINQAGE-SKKKFSLTVYVPPS 3057
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3111
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3112 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3168
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3169 VTLTCDATGIP 3179
Score = 82.6 bits (195), Expect = 5e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 1583
Score = 81.4 bits (192), Expect = 1e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSMLNM--TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + +N+ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 81.0 bits (191), Expect = 2e-14
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 19/275 (6%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG-SMLNMTKLTRHDAGIYTCEAVNS 245
++D PP T TW KDG P+ + S ISE S+L + D G YTCEA N
Sbjct: 2126 QSDAIPPP-TLTWLKDGHPLLKKPGLS-----ISENRSVLKIEDAQVQDTGRYTCEATNV 2179
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G N +V++ P I + E ++S + + ++ W++KG +
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 306 KSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNF 364
S+ + L I A+ + + CV +N G+A K++ L V +P + S +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA-KKEYNLQVYIRPTITNSGSH 2298
Query: 365 -VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
+ G+ L C+ + +P P+ TW K+G L + E H +L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH---------ILQ 2349
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ N+ SD G Y C A N G + L V + P
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 80.2 bits (189), Expect = 3e-14
Identities = 82/302 (27%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2344
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2345 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL I W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2405 SLTCEASGIPL--PSITWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2460 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2519 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 457 AP 458
+P
Sbjct: 2570 SP 2571
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3166 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3280
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3394
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3395 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 79.0 bits (186), Expect = 6e-14
Identities = 87/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 79.0 bits (186), Expect = 6e-14
Identities = 74/276 (26%), Positives = 117/276 (42%), Gaps = 29/276 (10%)
Query: 177 IENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDA 235
+E + ++ A G P PSIT W KDG P++ S+ + RI+S G ML + + T DA
Sbjct: 2399 VEKNSVSLTCEASGIPLPSIT--WFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDA 2452
Query: 236 GIYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
G YTC N+ G +SV P I ++ ++V + L+C GNP+
Sbjct: 2453 GQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PE 2510
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2511 ITWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVF 2568
Query: 354 FKPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI-- 2624
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2625 -------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 76.6 bits (180), Expect = 3e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4324
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4382
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4383 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4438
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4439 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4486
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4487 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3262 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 3374
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3375 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3432
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3484
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3485 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 1500
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 1501 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 1560
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 1561 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 1617
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 1674
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 1726 EVDVLVPP 1733
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3460 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3568
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3569 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3626
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3627 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3675
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2628
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2689 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2744
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2745 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2803
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2804 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2915 EDDHHKF 2921
Score = 70.1 bits (164), Expect = 3e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2209 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2265
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2323
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2324 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2381
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI------ 2435
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2436 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 1317
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 1318 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 1371
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2971 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 3025
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3086 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3143
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3144 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3203 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 62.9 bits (146), Expect = 5e-09
Identities = 79/316 (25%), Positives = 125/316 (39%), Gaps = 34/316 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVK--FKPEM 358
+ V P L I +AK E+ G + CV N G + Q DV ++V K
Sbjct: 2818 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P V N + + C PAP +W K+G L + + HK ++
Sbjct: 2876 SDLPEEVTVLVNKSAL--IECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSN 2924
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTL 476
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2925 GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 477 EW-VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2985 TCEVSGFPPPDLSWLK 3000
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4399
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4400 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4458
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4459 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4514
Query: 340 IGS 342
+GS
Sbjct: 4515 MGS 4517
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2660
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2717
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 3361
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 3362 IECRATGTPPPQINWLKNGLPL 3383
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL ++TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2406 LTC-EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2465 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2521
Score = 46.4 bits (105), Expect = 4e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3074 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3133 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNH 3189
Query: 158 IPVQNA 163
++N+
Sbjct: 3190 KRIENS 3195
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2499 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2558 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2614
Query: 159 PVQN 162
P+++
Sbjct: 2615 PLES 2618
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 2975 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3034 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3089
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3090 VITWYKNG 3097
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3446 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3504
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3505 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3561
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3562 WMKDGRPL 3569
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4434 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4477
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4007 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4066 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4116
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2759
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2818
Query: 161 QNA 163
++
Sbjct: 2819 TSS 2821
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3917
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3918 CTASGVPFPSIHWTKNGI 3935
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 1591
Score = 37.1 bits (82), Expect = 0.26
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2801 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 108 ETVTLNVHFAPEAVKVRAE--PDVLKPGIEATLICDSASSNPPATL-SWWRDGIPV 160
V + V P +K P+ + + + + + SS PA SW +DG P+
Sbjct: 2861 YDVRVLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3650
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3651 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3711 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3750
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
Score = 33.1 bits (72), Expect = 4.2
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLECESNAVPP-PVITWYKNG 3097
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 3098 RMITESTHVEILAD 3111
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 122 bits (294), Expect = 5e-27
Identities = 110/376 (29%), Positives = 164/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4049
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4050 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4105
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4106 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4160 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4217
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4218 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4271
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4272 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4320
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 4321 EDSGTYVCTAENSVGF 4336
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3062 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3115
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3176 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3233 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3289
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3290 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3919
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3920 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3973
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4031
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4032 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4087
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4137
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3634 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3688
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3746
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3747 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3804
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3805 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3855
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 474 VT 475
+T
Sbjct: 3916 IT 3917
Score = 93.1 bits (221), Expect = 4e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 91.9 bits (218), Expect = 9e-18
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 25/313 (7%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
K +N SVL I + D G Y C A N G + +++ P
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 459 -----DQVVSLTV 466
D++ LTV
Sbjct: 2196 NIGGSDELTQLTV 2208
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3547 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3606 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3662
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3722
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3840
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3899
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3900 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3948
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3949 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 83.8 bits (198), Expect = 2e-15
Identities = 83/302 (27%), Positives = 120/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2887 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2941
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 2999
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINQAGE-SKKKFSLTVYVPPS 3057
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3111
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3112 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3168
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3169 VTLTCDATGIP 3179
Score = 82.6 bits (195), Expect = 5e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 1583
Score = 81.4 bits (192), Expect = 1e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSMLNM--TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + +N+ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 81.0 bits (191), Expect = 2e-14
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 19/275 (6%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG-SMLNMTKLTRHDAGIYTCEAVNS 245
++D PP T TW KDG P+ + S ISE S+L + D G YTCEA N
Sbjct: 2126 QSDAIPPP-TLTWLKDGHPLLKKPGLS-----ISENRSVLKIEDAQVQDTGRYTCEATNV 2179
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G N +V++ P I + E ++S + + ++ W++KG +
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 306 KSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNF 364
S+ + L I A+ + + CV +N G+A K++ L V +P + S +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA-KKEYNLQVYIRPTITNSGSH 2298
Query: 365 -VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
+ G+ L C+ + +P P+ TW K+G L + E H +L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH---------ILQ 2349
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ N+ SD G Y C A N G + L V + P
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 80.2 bits (189), Expect = 3e-14
Identities = 82/302 (27%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2344
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2345 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL I W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2405 SLTCEASGIPL--PSITWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2460 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2519 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 457 AP 458
+P
Sbjct: 2570 SP 2571
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3166 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3280
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3394
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3395 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 79.0 bits (186), Expect = 6e-14
Identities = 87/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 79.0 bits (186), Expect = 6e-14
Identities = 74/276 (26%), Positives = 117/276 (42%), Gaps = 29/276 (10%)
Query: 177 IENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDA 235
+E + ++ A G P PSIT W KDG P++ S+ + RI+S G ML + + T DA
Sbjct: 2399 VEKNSVSLTCEASGIPLPSIT--WFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDA 2452
Query: 236 GIYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
G YTC N+ G +SV P I ++ ++V + L+C GNP+
Sbjct: 2453 GQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PE 2510
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2511 ITWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVF 2568
Query: 354 FKPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI-- 2624
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2625 -------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 76.6 bits (180), Expect = 3e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4324
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4382
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4383 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4438
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4439 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4486
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4487 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3262 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 3374
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3375 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3432
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3484
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3485 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 1500
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 1501 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 1560
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 1561 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 1617
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 1674
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 1726 EVDVLVPP 1733
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3460 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3568
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3569 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3626
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3627 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3675
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2628
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2689 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2744
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2745 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2803
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2804 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2915 EDDHHKF 2921
Score = 70.1 bits (164), Expect = 3e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2209 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2265
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2323
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2324 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2381
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI------ 2435
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2436 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 1317
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 1318 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 1371
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2971 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 3025
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3086 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3143
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3144 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3203 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 62.9 bits (146), Expect = 5e-09
Identities = 79/316 (25%), Positives = 125/316 (39%), Gaps = 34/316 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVK--FKPEM 358
+ V P L I +AK E+ G + CV N G + Q DV ++V K
Sbjct: 2818 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P V N + + C PAP +W K+G L + + HK ++
Sbjct: 2876 SDLPEEVTVLVNKSAL--IECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSN 2924
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTL 476
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2925 GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 477 EW-VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2985 TCEVSGFPPPDLSWLK 3000
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4399
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4400 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4458
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4459 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4514
Query: 340 IGS 342
+GS
Sbjct: 4515 MGS 4517
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2660
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2717
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 3361
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 3362 IECRATGTPPPQINWLKNGLPL 3383
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL ++TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2406 LTC-EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2465 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2521
Score = 46.4 bits (105), Expect = 4e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3074 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3133 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNH 3189
Query: 158 IPVQNA 163
++N+
Sbjct: 3190 KRIENS 3195
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2499 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2558 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2614
Query: 159 PVQN 162
P+++
Sbjct: 2615 PLES 2618
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 2975 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3034 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3089
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3090 VITWYKNG 3097
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3446 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3504
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3505 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3561
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3562 WMKDGRPL 3569
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4434 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4477
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4007 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4066 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4116
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2759
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2818
Query: 161 QNA 163
++
Sbjct: 2819 TSS 2821
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3917
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3918 CTASGVPFPSIHWTKNGI 3935
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 1591
Score = 37.1 bits (82), Expect = 0.26
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2801 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 108 ETVTLNVHFAPEAVKVRAE--PDVLKPGIEATLICDSASSNPPATL-SWWRDGIPV 160
V + V P +K P+ + + + + + SS PA SW +DG P+
Sbjct: 2861 YDVRVLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3650
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3651 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3711 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3750
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
Score = 33.1 bits (72), Expect = 4.2
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLECESNAVPP-PVITWYKNG 3097
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 3098 RMITESTHVEILAD 3111
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 122 bits (294), Expect = 5e-27
Identities = 110/376 (29%), Positives = 164/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4049
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4050 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4105
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4106 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4160 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4217
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4218 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4271
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4272 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4320
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 4321 EDSGTYVCTAENSVGF 4336
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3062 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3115
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3176 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3233 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3289
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3290 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3919
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3920 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3973
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4031
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4032 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4087
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4137
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3634 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3688
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3746
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3747 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3804
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3805 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3855
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 474 VT 475
+T
Sbjct: 3916 IT 3917
Score = 93.1 bits (221), Expect = 4e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 91.9 bits (218), Expect = 9e-18
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 25/313 (7%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
K +N SVL I + D G Y C A N G + +++ P
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 459 -----DQVVSLTV 466
D++ LTV
Sbjct: 2196 NIGGSDELTQLTV 2208
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3547 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3606 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3662
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3722
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3840
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3899
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3900 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3948
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3949 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 83.8 bits (198), Expect = 2e-15
Identities = 83/302 (27%), Positives = 120/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2887 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2941
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 2999
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINQAGE-SKKKFSLTVYVPPS 3057
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3111
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3112 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3168
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3169 VTLTCDATGIP 3179
Score = 82.6 bits (195), Expect = 5e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 1583
Score = 81.4 bits (192), Expect = 1e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSMLNM--TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + +N+ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 81.0 bits (191), Expect = 2e-14
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 19/275 (6%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG-SMLNMTKLTRHDAGIYTCEAVNS 245
++D PP T TW KDG P+ + S ISE S+L + D G YTCEA N
Sbjct: 2126 QSDAIPPP-TLTWLKDGHPLLKKPGLS-----ISENRSVLKIEDAQVQDTGRYTCEATNV 2179
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G N +V++ P I + E ++S + + ++ W++KG +
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 306 KSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNF 364
S+ + L I A+ + + CV +N G+A K++ L V +P + S +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA-KKEYNLQVYIRPTITNSGSH 2298
Query: 365 -VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
+ G+ L C+ + +P P+ TW K+G L + E H +L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH---------ILQ 2349
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ N+ SD G Y C A N G + L V + P
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 80.2 bits (189), Expect = 3e-14
Identities = 82/302 (27%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2344
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2345 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL I W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2405 SLTCEASGIPL--PSITWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2460 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2519 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 457 AP 458
+P
Sbjct: 2570 SP 2571
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3166 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3280
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3394
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3395 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 79.0 bits (186), Expect = 6e-14
Identities = 87/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 79.0 bits (186), Expect = 6e-14
Identities = 74/276 (26%), Positives = 117/276 (42%), Gaps = 29/276 (10%)
Query: 177 IENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDA 235
+E + ++ A G P PSIT W KDG P++ S+ + RI+S G ML + + T DA
Sbjct: 2399 VEKNSVSLTCEASGIPLPSIT--WFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDA 2452
Query: 236 GIYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
G YTC N+ G +SV P I ++ ++V + L+C GNP+
Sbjct: 2453 GQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PE 2510
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2511 ITWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVF 2568
Query: 354 FKPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI-- 2624
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2625 -------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 76.6 bits (180), Expect = 3e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4324
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4382
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4383 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4438
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4439 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4486
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4487 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3262 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 3374
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3375 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3432
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3484
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3485 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 1500
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 1501 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 1560
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 1561 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 1617
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 1674
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 1726 EVDVLVPP 1733
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3460 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3568
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3569 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3626
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3627 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3675
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2628
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2689 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2744
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2745 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2803
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2804 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2915 EDDHHKF 2921
Score = 70.1 bits (164), Expect = 3e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2209 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2265
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2323
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2324 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2381
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI------ 2435
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2436 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 1317
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 1318 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 1371
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2971 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 3025
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3086 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3143
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3144 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3203 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 62.9 bits (146), Expect = 5e-09
Identities = 79/316 (25%), Positives = 125/316 (39%), Gaps = 34/316 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVK--FKPEM 358
+ V P L I +AK E+ G + CV N G + Q DV ++V K
Sbjct: 2818 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P V N + + C PAP +W K+G L + + HK ++
Sbjct: 2876 SDLPEEVTVLVNKSAL--IECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSN 2924
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTL 476
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2925 GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 477 EW-VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2985 TCEVSGFPPPDLSWLK 3000
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4399
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4400 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4458
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4459 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4514
Query: 340 IGS 342
+GS
Sbjct: 4515 MGS 4517
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2660
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2717
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 3361
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 3362 IECRATGTPPPQINWLKNGLPL 3383
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL ++TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2406 LTC-EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2465 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2521
Score = 46.4 bits (105), Expect = 4e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3074 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3133 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNH 3189
Query: 158 IPVQNA 163
++N+
Sbjct: 3190 KRIENS 3195
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2499 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2558 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2614
Query: 159 PVQN 162
P+++
Sbjct: 2615 PLES 2618
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 2975 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3034 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3089
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3090 VITWYKNG 3097
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3446 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3504
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3505 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3561
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3562 WMKDGRPL 3569
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4434 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4477
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4007 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4066 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4116
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2759
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2818
Query: 161 QNA 163
++
Sbjct: 2819 TSS 2821
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3917
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3918 CTASGVPFPSIHWTKNGI 3935
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 1591
Score = 37.1 bits (82), Expect = 0.26
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2801 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 108 ETVTLNVHFAPEAVKVRAE--PDVLKPGIEATLICDSASSNPPATL-SWWRDGIPV 160
V + V P +K P+ + + + + + SS PA SW +DG P+
Sbjct: 2861 YDVRVLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3650
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3651 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3711 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3750
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
Score = 33.1 bits (72), Expect = 4.2
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLECESNAVPP-PVITWYKNG 3097
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 3098 RMITESTHVEILAD 3111
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 122 bits (294), Expect = 5e-27
Identities = 110/376 (29%), Positives = 164/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4049
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4050 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4105
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4106 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4160 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4217
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4218 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4271
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4272 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4320
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 4321 EDSGTYVCTAENSVGF 4336
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3062 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3115
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3176 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3233 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3289
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3290 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3919
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3920 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3973
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4031
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4032 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4087
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4137
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3634 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3688
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3746
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3747 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3804
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3805 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3855
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 474 VT 475
+T
Sbjct: 3916 IT 3917
Score = 93.1 bits (221), Expect = 4e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 91.9 bits (218), Expect = 9e-18
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 25/313 (7%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
K +N SVL I + D G Y C A N G + +++ P
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 459 -----DQVVSLTV 466
D++ LTV
Sbjct: 2196 NIGGSDELTQLTV 2208
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3547 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3606 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3662
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3722
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3840
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3899
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3900 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3948
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3949 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 83.8 bits (198), Expect = 2e-15
Identities = 83/302 (27%), Positives = 120/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2887 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2941
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 2999
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINQAGE-SKKKFSLTVYVPPS 3057
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3111
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3112 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3168
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3169 VTLTCDATGIP 3179
Score = 82.6 bits (195), Expect = 5e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 1583
Score = 81.4 bits (192), Expect = 1e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSMLNM--TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + +N+ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 81.0 bits (191), Expect = 2e-14
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 19/275 (6%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG-SMLNMTKLTRHDAGIYTCEAVNS 245
++D PP T TW KDG P+ + S ISE S+L + D G YTCEA N
Sbjct: 2126 QSDAIPPP-TLTWLKDGHPLLKKPGLS-----ISENRSVLKIEDAQVQDTGRYTCEATNV 2179
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G N +V++ P I + E ++S + + ++ W++KG +
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 306 KSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNF 364
S+ + L I A+ + + CV +N G+A K++ L V +P + S +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA-KKEYNLQVYIRPTITNSGSH 2298
Query: 365 -VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
+ G+ L C+ + +P P+ TW K+G L + E H +L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH---------ILQ 2349
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ N+ SD G Y C A N G + L V + P
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 80.2 bits (189), Expect = 3e-14
Identities = 82/302 (27%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2344
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2345 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL I W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2405 SLTCEASGIPL--PSITWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2460 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2519 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 457 AP 458
+P
Sbjct: 2570 SP 2571
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3166 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3280
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3394
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3395 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 79.0 bits (186), Expect = 6e-14
Identities = 87/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 79.0 bits (186), Expect = 6e-14
Identities = 74/276 (26%), Positives = 117/276 (42%), Gaps = 29/276 (10%)
Query: 177 IENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDA 235
+E + ++ A G P PSIT W KDG P++ S+ + RI+S G ML + + T DA
Sbjct: 2399 VEKNSVSLTCEASGIPLPSIT--WFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDA 2452
Query: 236 GIYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
G YTC N+ G +SV P I ++ ++V + L+C GNP+
Sbjct: 2453 GQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PE 2510
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2511 ITWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVF 2568
Query: 354 FKPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI-- 2624
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2625 -------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 76.6 bits (180), Expect = 3e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4324
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4382
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4383 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4438
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4439 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4486
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4487 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3262 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 3374
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3375 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3432
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3484
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3485 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 1500
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 1501 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 1560
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 1561 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 1617
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 1674
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 1726 EVDVLVPP 1733
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3460 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3568
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3569 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3626
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3627 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3675
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2628
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2689 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2744
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2745 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2803
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2804 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2915 EDDHHKF 2921
Score = 70.1 bits (164), Expect = 3e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2209 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2265
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2323
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2324 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2381
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI------ 2435
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2436 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 1317
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 1318 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 1371
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2971 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 3025
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3086 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3143
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3144 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3203 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 62.9 bits (146), Expect = 5e-09
Identities = 79/316 (25%), Positives = 125/316 (39%), Gaps = 34/316 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVK--FKPEM 358
+ V P L I +AK E+ G + CV N G + Q DV ++V K
Sbjct: 2818 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P V N + + C PAP +W K+G L + + HK ++
Sbjct: 2876 SDLPEEVTVLVNKSAL--IECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSN 2924
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTL 476
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2925 GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 477 EW-VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2985 TCEVSGFPPPDLSWLK 3000
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4399
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4400 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4458
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4459 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4514
Query: 340 IGS 342
+GS
Sbjct: 4515 MGS 4517
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2660
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2717
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 3361
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 3362 IECRATGTPPPQINWLKNGLPL 3383
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL ++TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2406 LTC-EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2465 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2521
Score = 46.4 bits (105), Expect = 4e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3074 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3133 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNH 3189
Query: 158 IPVQNA 163
++N+
Sbjct: 3190 KRIENS 3195
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2499 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2558 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2614
Query: 159 PVQN 162
P+++
Sbjct: 2615 PLES 2618
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 2975 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3034 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3089
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3090 VITWYKNG 3097
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3446 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3504
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3505 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3561
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3562 WMKDGRPL 3569
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4434 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4477
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4007 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4066 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4116
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2759
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2818
Query: 161 QNA 163
++
Sbjct: 2819 TSS 2821
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3917
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3918 CTASGVPFPSIHWTKNGI 3935
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 1591
Score = 37.1 bits (82), Expect = 0.26
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2801 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 108 ETVTLNVHFAPEAVKVRAE--PDVLKPGIEATLICDSASSNPPATL-SWWRDGIPV 160
V + V P +K P+ + + + + + SS PA SW +DG P+
Sbjct: 2861 YDVRVLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3650
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3651 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3711 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3750
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
Score = 33.1 bits (72), Expect = 4.2
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLECESNAVPP-PVITWYKNG 3097
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 3098 RMITESTHVEILAD 3111
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 122 bits (294), Expect = 5e-27
Identities = 110/376 (29%), Positives = 164/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4049
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4050 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4105
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4106 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4160 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4217
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4218 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4271
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4272 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4320
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 4321 EDSGTYVCTAENSVGF 4336
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3062 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3115
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3176 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3233 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3289
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3290 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3919
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3920 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3973
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4031
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4032 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4087
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4137
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3634 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3688
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3746
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3747 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3804
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3805 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3855
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 474 VT 475
+T
Sbjct: 3916 IT 3917
Score = 93.1 bits (221), Expect = 4e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 91.9 bits (218), Expect = 9e-18
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 25/313 (7%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
K +N SVL I + D G Y C A N G + +++ P
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 459 -----DQVVSLTV 466
D++ LTV
Sbjct: 2196 NIGGSDELTQLTV 2208
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3547 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3606 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3662
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3722
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3840
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3899
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3900 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3948
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3949 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 83.8 bits (198), Expect = 2e-15
Identities = 83/302 (27%), Positives = 120/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2887 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2941
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 2999
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINQAGE-SKKKFSLTVYVPPS 3057
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3111
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3112 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3168
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3169 VTLTCDATGIP 3179
Score = 82.6 bits (195), Expect = 5e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 1583
Score = 81.4 bits (192), Expect = 1e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSMLNM--TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + +N+ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 81.0 bits (191), Expect = 2e-14
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 19/275 (6%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG-SMLNMTKLTRHDAGIYTCEAVNS 245
++D PP T TW KDG P+ + S ISE S+L + D G YTCEA N
Sbjct: 2126 QSDAIPPP-TLTWLKDGHPLLKKPGLS-----ISENRSVLKIEDAQVQDTGRYTCEATNV 2179
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G N +V++ P I + E ++S + + ++ W++KG +
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 306 KSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNF 364
S+ + L I A+ + + CV +N G+A K++ L V +P + S +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA-KKEYNLQVYIRPTITNSGSH 2298
Query: 365 -VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
+ G+ L C+ + +P P+ TW K+G L + E H +L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH---------ILQ 2349
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ N+ SD G Y C A N G + L V + P
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 80.2 bits (189), Expect = 3e-14
Identities = 82/302 (27%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2344
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2345 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL I W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2405 SLTCEASGIPL--PSITWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2460 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2519 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 457 AP 458
+P
Sbjct: 2570 SP 2571
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3166 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3280
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3394
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3395 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 79.0 bits (186), Expect = 6e-14
Identities = 87/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 79.0 bits (186), Expect = 6e-14
Identities = 74/276 (26%), Positives = 117/276 (42%), Gaps = 29/276 (10%)
Query: 177 IENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDA 235
+E + ++ A G P PSIT W KDG P++ S+ + RI+S G ML + + T DA
Sbjct: 2399 VEKNSVSLTCEASGIPLPSIT--WFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDA 2452
Query: 236 GIYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
G YTC N+ G +SV P I ++ ++V + L+C GNP+
Sbjct: 2453 GQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PE 2510
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2511 ITWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVF 2568
Query: 354 FKPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI-- 2624
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2625 -------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 76.6 bits (180), Expect = 3e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4324
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4382
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4383 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4438
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4439 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4486
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4487 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3262 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 3374
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3375 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3432
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3484
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3485 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 1500
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 1501 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 1560
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 1561 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 1617
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 1674
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 1726 EVDVLVPP 1733
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3460 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3568
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3569 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3626
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3627 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3675
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2628
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2689 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2744
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2745 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2803
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2804 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2915 EDDHHKF 2921
Score = 70.1 bits (164), Expect = 3e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2209 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2265
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2323
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2324 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2381
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI------ 2435
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2436 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 1317
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 1318 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 1371
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2971 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 3025
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3086 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3143
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3144 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3203 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 62.9 bits (146), Expect = 5e-09
Identities = 79/316 (25%), Positives = 125/316 (39%), Gaps = 34/316 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVK--FKPEM 358
+ V P L I +AK E+ G + CV N G + Q DV ++V K
Sbjct: 2818 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P V N + + C PAP +W K+G L + + HK ++
Sbjct: 2876 SDLPEEVTVLVNKSAL--IECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSN 2924
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTL 476
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2925 GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 477 EW-VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2985 TCEVSGFPPPDLSWLK 3000
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4399
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4400 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4458
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4459 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4514
Query: 340 IGS 342
+GS
Sbjct: 4515 MGS 4517
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2660
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2717
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 3361
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 3362 IECRATGTPPPQINWLKNGLPL 3383
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL ++TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2406 LTC-EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2465 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2521
Score = 46.4 bits (105), Expect = 4e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3074 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3133 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNH 3189
Query: 158 IPVQNA 163
++N+
Sbjct: 3190 KRIENS 3195
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2499 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2558 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2614
Query: 159 PVQN 162
P+++
Sbjct: 2615 PLES 2618
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 2975 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3034 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3089
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3090 VITWYKNG 3097
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3446 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3504
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3505 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3561
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3562 WMKDGRPL 3569
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4434 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4477
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4007 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4066 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4116
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2759
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2818
Query: 161 QNA 163
++
Sbjct: 2819 TSS 2821
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3917
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3918 CTASGVPFPSIHWTKNGI 3935
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 1591
Score = 37.1 bits (82), Expect = 0.26
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2801 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 108 ETVTLNVHFAPEAVKVRAE--PDVLKPGIEATLICDSASSNPPATL-SWWRDGIPV 160
V + V P +K P+ + + + + + SS PA SW +DG P+
Sbjct: 2861 YDVRVLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3650
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3651 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3711 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3750
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
Score = 33.1 bits (72), Expect = 4.2
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLECESNAVPP-PVITWYKNG 3097
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 3098 RMITESTHVEILAD 3111
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 122 bits (294), Expect = 5e-27
Identities = 110/376 (29%), Positives = 164/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4049
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4050 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4105
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4106 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4160 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4217
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4218 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4271
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4272 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4320
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 4321 EDSGTYVCTAENSVGF 4336
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3062 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3115
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3176 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3233 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3289
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3290 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3919
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3920 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3973
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4031
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4032 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4087
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4137
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3634 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3688
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3746
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3747 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3804
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3805 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3855
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 474 VT 475
+T
Sbjct: 3916 IT 3917
Score = 93.1 bits (221), Expect = 4e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 91.9 bits (218), Expect = 9e-18
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 25/313 (7%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
K +N SVL I + D G Y C A N G + +++ P
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 459 -----DQVVSLTV 466
D++ LTV
Sbjct: 2196 NIGGSDELTQLTV 2208
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3547 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3606 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3662
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3722
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3840
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3899
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3900 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3948
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3949 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 83.8 bits (198), Expect = 2e-15
Identities = 83/302 (27%), Positives = 120/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2887 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2941
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 2999
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINQAGE-SKKKFSLTVYVPPS 3057
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3111
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3112 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3168
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3169 VTLTCDATGIP 3179
Score = 82.6 bits (195), Expect = 5e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 1583
Score = 81.4 bits (192), Expect = 1e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSMLNM--TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + +N+ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 81.0 bits (191), Expect = 2e-14
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 19/275 (6%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG-SMLNMTKLTRHDAGIYTCEAVNS 245
++D PP T TW KDG P+ + S ISE S+L + D G YTCEA N
Sbjct: 2126 QSDAIPPP-TLTWLKDGHPLLKKPGLS-----ISENRSVLKIEDAQVQDTGRYTCEATNV 2179
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G N +V++ P I + E ++S + + ++ W++KG +
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 306 KSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNF 364
S+ + L I A+ + + CV +N G+A K++ L V +P + S +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA-KKEYNLQVYIRPTITNSGSH 2298
Query: 365 -VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
+ G+ L C+ + +P P+ TW K+G L + E H +L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH---------ILQ 2349
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ N+ SD G Y C A N G + L V + P
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 80.2 bits (189), Expect = 3e-14
Identities = 82/302 (27%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2344
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2345 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL I W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2405 SLTCEASGIPL--PSITWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2460 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2519 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 457 AP 458
+P
Sbjct: 2570 SP 2571
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3166 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3280
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3394
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3395 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 79.0 bits (186), Expect = 6e-14
Identities = 87/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 79.0 bits (186), Expect = 6e-14
Identities = 74/276 (26%), Positives = 117/276 (42%), Gaps = 29/276 (10%)
Query: 177 IENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDA 235
+E + ++ A G P PSIT W KDG P++ S+ + RI+S G ML + + T DA
Sbjct: 2399 VEKNSVSLTCEASGIPLPSIT--WFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDA 2452
Query: 236 GIYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
G YTC N+ G +SV P I ++ ++V + L+C GNP+
Sbjct: 2453 GQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PE 2510
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2511 ITWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVF 2568
Query: 354 FKPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI-- 2624
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2625 -------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 76.6 bits (180), Expect = 3e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4324
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4382
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4383 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4438
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4439 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4486
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4487 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3262 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 3374
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3375 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3432
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3484
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3485 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 1500
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 1501 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 1560
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 1561 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 1617
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 1674
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 1726 EVDVLVPP 1733
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3460 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3568
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3569 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3626
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3627 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3675
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2628
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2689 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2744
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2745 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2803
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2804 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2915 EDDHHKF 2921
Score = 70.1 bits (164), Expect = 3e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2209 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2265
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2323
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2324 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2381
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI------ 2435
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2436 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 1317
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 1318 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 1371
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2971 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 3025
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3086 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3143
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3144 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3203 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 62.9 bits (146), Expect = 5e-09
Identities = 79/316 (25%), Positives = 125/316 (39%), Gaps = 34/316 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVK--FKPEM 358
+ V P L I +AK E+ G + CV N G + Q DV ++V K
Sbjct: 2818 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P V N + + C PAP +W K+G L + + HK ++
Sbjct: 2876 SDLPEEVTVLVNKSAL--IECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSN 2924
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTL 476
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2925 GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 477 EW-VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2985 TCEVSGFPPPDLSWLK 3000
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4399
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4400 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4458
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4459 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4514
Query: 340 IGS 342
+GS
Sbjct: 4515 MGS 4517
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2660
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2717
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 3361
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 3362 IECRATGTPPPQINWLKNGLPL 3383
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL ++TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2406 LTC-EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2465 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2521
Score = 46.4 bits (105), Expect = 4e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3074 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3133 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNH 3189
Query: 158 IPVQNA 163
++N+
Sbjct: 3190 KRIENS 3195
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2499 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2558 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2614
Query: 159 PVQN 162
P+++
Sbjct: 2615 PLES 2618
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 2975 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3034 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3089
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3090 VITWYKNG 3097
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3446 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3504
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3505 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3561
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3562 WMKDGRPL 3569
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4434 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4477
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4007 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4066 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4116
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2759
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2818
Query: 161 QNA 163
++
Sbjct: 2819 TSS 2821
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3917
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3918 CTASGVPFPSIHWTKNGI 3935
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 1591
Score = 37.1 bits (82), Expect = 0.26
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2801 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 108 ETVTLNVHFAPEAVKVRAE--PDVLKPGIEATLICDSASSNPPATL-SWWRDGIPV 160
V + V P +K P+ + + + + + SS PA SW +DG P+
Sbjct: 2861 YDVRVLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3650
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3651 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3711 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3750
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
Score = 33.1 bits (72), Expect = 4.2
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLECESNAVPP-PVITWYKNG 3097
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 3098 RMITESTHVEILAD 3111
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 122 bits (294), Expect = 5e-27
Identities = 110/376 (29%), Positives = 164/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4049
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4050 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4105
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4106 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4160 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4217
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4218 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4271
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4272 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4320
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 4321 EDSGTYVCTAENSVGF 4336
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3062 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3115
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3176 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3233 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3289
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3290 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3919
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3920 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3973
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4031
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4032 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4087
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4137
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3634 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3688
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3746
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3747 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3804
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3805 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3855
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 474 VT 475
+T
Sbjct: 3916 IT 3917
Score = 93.1 bits (221), Expect = 4e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 91.9 bits (218), Expect = 9e-18
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 25/313 (7%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
K +N SVL I + D G Y C A N G + +++ P
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 459 -----DQVVSLTV 466
D++ LTV
Sbjct: 2196 NIGGSDELTQLTV 2208
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3547 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3606 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3662
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3722
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3840
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3899
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3900 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3948
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3949 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 83.8 bits (198), Expect = 2e-15
Identities = 83/302 (27%), Positives = 120/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2887 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2941
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 2999
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINQAGE-SKKKFSLTVYVPPS 3057
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3111
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3112 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3168
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3169 VTLTCDATGIP 3179
Score = 82.6 bits (195), Expect = 5e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 1583
Score = 81.4 bits (192), Expect = 1e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSMLNM--TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + +N+ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 81.0 bits (191), Expect = 2e-14
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 19/275 (6%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG-SMLNMTKLTRHDAGIYTCEAVNS 245
++D PP T TW KDG P+ + S ISE S+L + D G YTCEA N
Sbjct: 2126 QSDAIPPP-TLTWLKDGHPLLKKPGLS-----ISENRSVLKIEDAQVQDTGRYTCEATNV 2179
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G N +V++ P I + E ++S + + ++ W++KG +
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 306 KSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNF 364
S+ + L I A+ + + CV +N G+A K++ L V +P + S +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA-KKEYNLQVYIRPTITNSGSH 2298
Query: 365 -VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
+ G+ L C+ + +P P+ TW K+G L + E H +L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH---------ILQ 2349
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ N+ SD G Y C A N G + L V + P
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 80.2 bits (189), Expect = 3e-14
Identities = 82/302 (27%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2344
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2345 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL I W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2405 SLTCEASGIPL--PSITWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2460 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2519 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 457 AP 458
+P
Sbjct: 2570 SP 2571
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3166 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3280
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3394
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3395 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 79.0 bits (186), Expect = 6e-14
Identities = 87/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 79.0 bits (186), Expect = 6e-14
Identities = 74/276 (26%), Positives = 117/276 (42%), Gaps = 29/276 (10%)
Query: 177 IENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDA 235
+E + ++ A G P PSIT W KDG P++ S+ + RI+S G ML + + T DA
Sbjct: 2399 VEKNSVSLTCEASGIPLPSIT--WFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDA 2452
Query: 236 GIYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
G YTC N+ G +SV P I ++ ++V + L+C GNP+
Sbjct: 2453 GQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PE 2510
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2511 ITWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVF 2568
Query: 354 FKPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI-- 2624
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2625 -------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 76.6 bits (180), Expect = 3e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4324
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4382
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4383 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4438
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4439 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4486
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4487 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3262 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 3374
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3375 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3432
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3484
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3485 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 1500
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 1501 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 1560
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 1561 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 1617
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 1674
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 1726 EVDVLVPP 1733
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3460 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3568
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3569 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3626
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3627 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3675
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2628
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2689 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2744
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2745 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2803
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2804 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2915 EDDHHKF 2921
Score = 70.1 bits (164), Expect = 3e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2209 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2265
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2323
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2324 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2381
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI------ 2435
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2436 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 1317
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 1318 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 1371
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2971 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 3025
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3086 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3143
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3144 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3203 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 62.9 bits (146), Expect = 5e-09
Identities = 79/316 (25%), Positives = 125/316 (39%), Gaps = 34/316 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVK--FKPEM 358
+ V P L I +AK E+ G + CV N G + Q DV ++V K
Sbjct: 2818 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P V N + + C PAP +W K+G L + + HK ++
Sbjct: 2876 SDLPEEVTVLVNKSAL--IECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSN 2924
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTL 476
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2925 GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 477 EW-VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2985 TCEVSGFPPPDLSWLK 3000
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4399
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4400 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4458
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4459 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4514
Query: 340 IGS 342
+GS
Sbjct: 4515 MGS 4517
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2660
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2717
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 3361
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 3362 IECRATGTPPPQINWLKNGLPL 3383
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL ++TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2406 LTC-EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2465 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2521
Score = 46.4 bits (105), Expect = 4e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3074 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3133 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNH 3189
Query: 158 IPVQNA 163
++N+
Sbjct: 3190 KRIENS 3195
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2499 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2558 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2614
Query: 159 PVQN 162
P+++
Sbjct: 2615 PLES 2618
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 2975 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3034 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3089
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3090 VITWYKNG 3097
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3446 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3504
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3505 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3561
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3562 WMKDGRPL 3569
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4434 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4477
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4007 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4066 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4116
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2759
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2818
Query: 161 QNA 163
++
Sbjct: 2819 TSS 2821
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3917
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3918 CTASGVPFPSIHWTKNGI 3935
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 1591
Score = 37.1 bits (82), Expect = 0.26
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2801 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 108 ETVTLNVHFAPEAVKVRAE--PDVLKPGIEATLICDSASSNPPATL-SWWRDGIPV 160
V + V P +K P+ + + + + + SS PA SW +DG P+
Sbjct: 2861 YDVRVLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3650
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3651 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3711 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3750
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
Score = 33.1 bits (72), Expect = 4.2
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLECESNAVPP-PVITWYKNG 3097
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 3098 RMITESTHVEILAD 3111
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 122 bits (294), Expect = 5e-27
Identities = 110/376 (29%), Positives = 164/376 (43%), Gaps = 35/376 (9%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE--AVKVRAEPDVLKPG 133
+ + S L + +N CEAT + + ++ +NV+ + AV + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAV 4049
Query: 134 IE--ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
E T +C + NP T + + + VQ P+ + ++ +P+ +S ADG
Sbjct: 4050 REDAGTYMC--VAQNPAGT-ALGKIKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGL 4105
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
PP TW KDG I +S R++S GS L + + DAG YTC A N G++
Sbjct: 4106 PPP-DITWHKDGRAIVESI----RQRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVT 309
+ ++VH P I+S + N N A+L C A G P A I W++ + T
Sbjct: 4160 STKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYT 4217
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
EP LI+ E+ G + CV NN G T V L V P P V +
Sbjct: 4218 AEP---YGELILENVVLEDSGFYTCVANNAAGEDT-HTVSLTVHVLPTFTELPGDV--SL 4271
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
N G+ RL CK +P P TW+ N +P A F D + S L+I V+
Sbjct: 4272 NKGEQLRLSCKATGIPLPKLTWTFNNNIIP--------AHF---DSVNGHSELVIERVSK 4320
Query: 430 SDYGSYECGARNELGF 445
D G+Y C A N +GF
Sbjct: 4321 EDSGTYVCTAENSVGF 4336
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 1874
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 1875 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1935 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1990
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1991 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 2047
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 2048 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 454 VTSAPD 459
V P+
Sbjct: 2100 VYVPPN 2105
Score = 94.7 bits (225), Expect = 1e-18
Identities = 82/296 (27%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGN--PPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
D+ S + V + E +S+ + N PP + TW K+G IT+S++ I+++G ML
Sbjct: 3062 DSESLSVVNVR-EGTSVSLECESNAVPPPVI-TWYKNGRMITESTHVE----ILADGQML 3115
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTA 284
++ K D G Y C A+N G N ++V+ P I+ + V+ + V L+C A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLT--SYLIIRKAKSENLGNFQCVVNNGIGS 342
G P I W K +K S + E + L+ S L I +++ + GN+ C+ +N G
Sbjct: 3176 TGIP--PPTIAW-LKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
A K L ++ P + + + +G+ L+C +P P W K+G P+ +
Sbjct: 3233 AQKY-YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDG--KPIAS 3289
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
N S L I TSD G Y C A N G L+V P
Sbjct: 3290 GETERIRVSANG-----STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 27/332 (8%)
Query: 129 VLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP-IFDDTTSYNTVGIENEPLIISVR 187
++ P ++ T + +N D + VQ P I D+ T + ++ P +I+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVD-LTVQVPPSIADEPTDFLVT--KHAPAVITCT 3919
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P PSI WTK+G+ + RI+S G++ + H AG YTC A N+
Sbjct: 3920 ASGVPFPSIH--WTKNGIRLLPRG---DGYRILSSGAIEILATQLNH-AGRYTCVARNAA 3973
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A ++++ VH P I+ + N +L C A G P + I W+++G ++
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTP--SPFITWQKEGINVNTS 4031
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ L I +A E+ G + CV N G+A + + L V+ P + SP+ +
Sbjct: 4032 GRNHAVLP-SGGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQVPPVI--SPHLKE 4087
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
V + L C+ +P P TW K+G + + + + L I
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI----------RQRVLSSGSLQIAF 4137
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V D G Y C A N G S+T+ KL V P
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 93.9 bits (223), Expect = 2e-18
Identities = 76/302 (25%), Positives = 123/302 (40%), Gaps = 21/302 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ N + + ++D PP + TW ++G + ++ RI+S G L + D
Sbjct: 3634 LRNRQVTLECKSDAVPPPVI-TWLRNG----ERLQATPRVRILSGGRYLQINNADLGDTA 3688
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N G ++V+ P IK Q++V N+ VL C A G P I W
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVP--TPRITW 3746
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ G + + +L I+ A + G + C+ N G+ ++ + L V P
Sbjct: 3747 RKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMATNAAGT-DRRRIDLQVHVPP 3804
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ P + NV L C+ +P PS W KNG L V+ + + +
Sbjct: 3805 SIAPGPTNMTVIVNVQTT--LACEATGIPKPSINWRKNGHLLNVDQNQNSY-------RL 3855
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHST 473
+ L+I + + D +YEC N G TV L V P D+ VT +
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 474 VT 475
+T
Sbjct: 3916 IT 3917
Score = 93.1 bits (221), Expect = 4e-18
Identities = 81/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG I + +I+ G L +
Sbjct: 1739 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLIDERD----GFKILLNGRKLVI 1792
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 1793 AQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 1851
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 1852 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 1908
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1969 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Score = 91.9 bits (218), Expect = 9e-18
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 25/313 (7%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 1915 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1969
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1970 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 2030 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 2088 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 2144
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
K +N SVL I + D G Y C A N G + +++ P
Sbjct: 2145 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Query: 459 -----DQVVSLTV 466
D++ LTV
Sbjct: 2196 NIGGSDELTQLTV 2208
Score = 91.9 bits (218), Expect = 9e-18
Identities = 110/460 (23%), Positives = 175/460 (38%), Gaps = 61/460 (13%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L CI++G P +TW K+ + + T + + I T ++ +Y C A++ A
Sbjct: 3547 ELTCIASG-IPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ + + VH P D+ + + TL C S + PP ++W R+G +
Sbjct: 3606 GDDD--KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAVPPPVITWLRNGERL 3662
Query: 161 QNAP----------------IFDDTTSY-----NTVGIENEPLIISVRA----DGNPPSI 195
Q P DT +Y N G I++V G P S+
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSL 3722
Query: 196 TYTWTK--------DGLPITQSSYS------SGNDR--IISEGSMLNMTKLTRHDAGIYT 239
K +G+P + ++ +GN I E L++ D G Y
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G I + VH P I N+ N L+C A G P I W +
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKN 3840
Query: 300 GYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
G+ ++ + L+S L+I ++ ++C V NG G K+ V L V+ P +
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD-DKRTVDLTVQVPPSI 3899
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P + V + C VP PS W+KNG++L + Y I
Sbjct: 3900 ADEPTDFLVTKHAPAV--ITCTASGVPFPSIHWTKNGIRL-LPRGDGY--------RILS 3948
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + I + G Y C ARN G + V L V P
Sbjct: 3949 SGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 83.8 bits (198), Expect = 2e-15
Identities = 83/302 (27%), Positives = 120/302 (39%), Gaps = 25/302 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 889 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 943
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 944 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 1002
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 1003 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 1059
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 1060 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 1115
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 1116 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV 1169
Query: 457 AP 458
P
Sbjct: 1170 PP 1171
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/311 (26%), Positives = 125/311 (40%), Gaps = 27/311 (8%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
N+ +I + G+P +W KDG P+ + + + +S G +L + D G Y
Sbjct: 2887 NKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHH----KFLSNGRILQILNTQITDIGRY 2941
Query: 239 TCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
C A N+ G+A +++VH P I S+N+ N L+C G P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL 2999
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+ I + T + IIR AK + G + C+ N G +K+ L V P
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIR-AKVSDGGEYTCIAINQAGE-SKKKFSLTVYVPPS 3057
Query: 358 MDTSPNFVKSASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
+ + S NV G L C+ +VP P TW KNG + +T + A+
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD------ 3111
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD------QVVSLTVTNV 469
+L I SD G Y C A N G L+V P +V+ T++N
Sbjct: 3112 ---GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP 3168
Query: 470 THSTVTLEWVP 480
T +P
Sbjct: 3169 VTLTCDATGIP 3179
Score = 82.6 bits (195), Expect = 5e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 1315
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 1316 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 1373
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 1374 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGKILKLFRATPEDAGRYS 1430
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 1431 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 1489 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 1583
Score = 81.4 bits (192), Expect = 1e-14
Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 23/264 (8%)
Query: 204 LPITQSSYSSGNDRIISEGSMLNM--TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPA 261
L ++ + G D+ + E + +N+ K+T D G Y C AV+S G A V P
Sbjct: 461 LSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP 520
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI---DPKSVTFEPKNLTSY 318
+ V NV P E AVL+C I + ++ W+R + +P + NL+
Sbjct: 521 PVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAEPARIR-TLANLS-- 575
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLM 378
L ++ K + G + C+V++ G ++ V L V+ P++ P + G +M
Sbjct: 576 LELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEPPKVTVMPK--NQSFTGGSEVSIM 632
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C P P W+ N + + H+ +T L I N A D G Y C
Sbjct: 633 CSATGYPKPKIAWTVNDM---------FIVGSHRY-RMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 439 ARNELGFSTTTVKLDVTSAPDQVV 462
A N G L AP +V
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMV 706
Score = 81.0 bits (191), Expect = 2e-14
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 19/275 (6%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG-SMLNMTKLTRHDAGIYTCEAVNS 245
++D PP T TW KDG P+ + S ISE S+L + D G YTCEA N
Sbjct: 2126 QSDAIPPP-TLTWLKDGHPLLKKPGLS-----ISENRSVLKIEDAQVQDTGRYTCEATNV 2179
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G N +V++ P I + E ++S + + ++ W++KG +
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 306 KSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNF 364
S+ + L I A+ + + CV +N G+A K++ L V +P + S +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA-KKEYNLQVYIRPTITNSGSH 2298
Query: 365 -VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
+ G+ L C+ + +P P+ TW K+G L + E H +L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH---------ILQ 2349
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ N+ SD G Y C A N G + L V + P
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 80.2 bits (189), Expect = 3e-14
Identities = 82/302 (27%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRAD--GNPPSITYTWTKDGLPITQSSYSSGNDRIISE 221
P ++ S+ T I IS+ + G PP T TW KDG P+ ++ I+ E
Sbjct: 2290 PTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-TVTWMKDGHPLIKAK----GVEILDE 2344
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI---KSVSQNVVANPNEDA 278
G +L + + D G Y C AVN G +SVH P I +N+
Sbjct: 2345 GHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSV 2404
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIR--KAKSENLGNFQCVV 336
L+C A G PL I W + G+ P S++ + L+ ++R + E+ G + CVV
Sbjct: 2405 SLTCEASGIPL--PSITWFKDGW---PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G K L V P + Q L C+ P P TW K+G
Sbjct: 2460 RNAAGEERK-IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L E + I+ L I NV G Y C A + G + + L+V
Sbjct: 2519 PL---------QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Query: 457 AP 458
+P
Sbjct: 2570 SP 2571
Score = 79.4 bits (187), Expect = 5e-14
Identities = 74/295 (25%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ P+ ++ A G PP T W K+ I S S RI+S GS L + + D+G Y
Sbjct: 3166 SNPVTLTCDATGIPPP-TIAWLKNHKRIENSD--SLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 239 TCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
TC A N +G A +S+ P + + +V E+ L C A G P I+W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIP--TPLIQW 3280
Query: 297 ERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+ G I ++ S L I A + + G + CV N G + + +
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
K + V + C+ P P W KNG+ LP+++ + A
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAA------ 3394
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
V+ I SD Y C A N G L V + P+ S+ +T
Sbjct: 3395 ---GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 79.0 bits (186), Expect = 6e-14
Identities = 87/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 1659 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 1713
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 1714 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 1771
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G ID + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 1772 GQLIDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKKEFEVTVHVPPTIK 1829
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 1830 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 1879
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 1880 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1939
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1940 LECKAAGNPVPVITWYK 1956
Score = 79.0 bits (186), Expect = 6e-14
Identities = 74/276 (26%), Positives = 117/276 (42%), Gaps = 29/276 (10%)
Query: 177 IENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDA 235
+E + ++ A G P PSIT W KDG P++ S+ + RI+S G ML + + T DA
Sbjct: 2399 VEKNSVSLTCEASGIPLPSIT--WFKDGWPVSLSN----SVRILSGGRMLRLMQTTMEDA 2452
Query: 236 GIYTCEAVNSQGAAVANISVSVHYPAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
G YTC N+ G +SV P I ++ ++V + L+C GNP+
Sbjct: 2453 GQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPV--PE 2510
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W + G + + + +L I + + G + C+ ++ G ++ L V
Sbjct: 2511 ITWHKDGQPLQ-EDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR-SFSLNVF 2568
Query: 354 FKPEM-----DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
P + D +P V N L+C+ S P + TW K+G L N + +
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILN--SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI-- 2624
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L I N + G Y C A NE G
Sbjct: 2625 -------LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 76.6 bits (180), Expect = 3e-13
Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E L +S +A G P P +T+T+ + +P S + ++ +I ++++ D+G
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIE--------RVSKEDSG 4324
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A NS G A V V P K N + +A+L+C G+P I+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQ 4382
Query: 296 WERKGYKIDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W RKG I+ ++ + L L I +E+ G++ CV N G ++ + L ++
Sbjct: 4383 WNRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG-VVERSMSLTLQS 4438
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P V++ N G L C+ P P+ TWS+ G + +
Sbjct: 4439 PPIITLEP--VETVINAGGKIILNCQATGEPQPTITWSRQG----------HSISWDDRV 4486
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
++ + L I + D +EC ARN +G
Sbjct: 4487 NVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 74.9 bits (176), Expect = 1e-12
Identities = 77/284 (27%), Positives = 113/284 (39%), Gaps = 21/284 (7%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
EN L+ + A+G P + W KDG PI +S + R+ + GS LN+ D G
Sbjct: 3262 ENVELVCN--ANGIPTPLIQ-WLKDGKPI--ASGETERIRVSANGSTLNIYGALTSDTGK 3316
Query: 238 YTCEAVNSQGAA--VANISVSVHYPA-GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
YTC A N G + N++V V G K ++ ++ + + C A G P I
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQI 3374
Query: 295 KWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W + G + P S + I +A+ ++ + CV +N G K L V
Sbjct: 3375 NWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKH-YNLQVFA 3432
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P MD S + G + C PAPS W ++G L ++
Sbjct: 3433 PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------- 3484
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T+ VL + T D G Y C A NE G + L V P
Sbjct: 3485 -STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 1446 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 1500
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 1501 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 1560
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 1561 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 1617
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 1674
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 1726 EVDVLVPP 1733
Score = 73.3 bits (172), Expect = 3e-12
Identities = 75/279 (26%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 DGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
DG P PS+ W +DG P+ ++ + + + G +L + K D+G YTC A N G
Sbjct: 3460 DGTPAPSMA--WLRDGQPLGLDAHLT----VSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 248 AAVANISVSVHYPAGIKSVSQN-----VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+ + V P I ++ +V NP E L+C A G P A + W + G
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE---LTCIASGIP--APKMTWMKDGRP 3568
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DT 360
+ P++ + L I A+ E+ G + C+ ++ G K + ++ V P +
Sbjct: 3569 L-PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK-EYLVRVHVPPNIAGTD 3626
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
P + N QV L CK +VP P TW +NG +L + ++
Sbjct: 3627 EPRDITVLRN-RQV-TLECKSDAVPPPVITWLRNGERLQATPRVRI---------LSGGR 3675
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
L INN D +Y C A N G +T L V P+
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/367 (23%), Positives = 138/367 (37%), Gaps = 44/367 (11%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
A + D + I N P + A PP+ T TW KDG P+ S+ N RI+ G
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA-TITWFKDGTPLE----SNRNIRILPGG 2628
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--------VSQNVVANP 274
L + +AG Y+C A N G + + V V+ P I + V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C A P + + W + G + V T L I++A+ + G +
Sbjct: 2689 NNTLTLECEAYAIP--SASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYT 2744
Query: 334 CVVNNGIGSATKQDVMLIVKFKPE----------MDTSPNFVKSASNVGQVGRLMCKCKS 383
CV +N I + D + ++ P +DT N + L C+ +
Sbjct: 2745 CVASN-IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNA 2803
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
P P+ TW K+G P+ +S K + VL I D G Y C A NE
Sbjct: 2804 APPPTLTWYKDG--HPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 444 GFSTTTVKLDVTSAP-----DQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
G + + V P + + VT + + + +E + G SW + +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
Query: 498 FDDSYKY 504
DD +K+
Sbjct: 2915 EDDHHKF 2921
Score = 70.1 bits (164), Expect = 3e-11
Identities = 70/297 (23%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
IE + + + G PP W K G P+ S G RI+S G L ++ + DA
Sbjct: 2209 IEGNLISLLCESSGIPPP-NLIWKKKGSPVLTDSM--GRVRILSGGRQLQISIAEKSDAA 2265
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQN---VVANPNEDAVLSCTAIGNPLLAEH 293
+Y+C A N G A ++ V+ I + + ++ + L C G P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIP--PPT 2323
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ W + G+ + K+ E + L ++ + G + CV N G K+ L V
Sbjct: 2324 VTWMKDGHPLI-KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKK-YDLSVH 2381
Query: 354 FKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + + ++ S V + L C+ +P PS TW K+G + ++ S +
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI------ 2435
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV 469
++ +L + D G Y C RN G L V P V T+ +V
Sbjct: 2436 ---LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 1092 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 1146
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 1204
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 1205 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 1260
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 1261 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 1317
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 1318 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 1371
Score = 68.5 bits (160), Expect = 9e-11
Identities = 71/276 (25%), Positives = 111/276 (40%), Gaps = 17/276 (6%)
Query: 171 SYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL 230
S N + N + ++ G PP +W K+ PI ++ N I+ G L + +
Sbjct: 2971 SENLTVVVNNFISLTCEVSGFPPP-DLSWLKNEQPIKLNT----NTLIVPGGRTLQIIRA 3025
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS-VSQNV-VANPNEDAVLSCTAIGNP 288
D G YTC A+N G + S++V+ P IK S+++ V N E +S N
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
+ I W + G I +S E L I+KA+ + G + C N G K +
Sbjct: 3086 VPPPVITWYKNGRMI-TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDK-NF 3143
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA 408
L V P ++ P + L C +P P+ W KN ++ + S +
Sbjct: 3144 HLNVYVPPSIE-GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
++ S L I SD G+Y C A N G
Sbjct: 3203 -------LSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/256 (26%), Positives = 110/256 (42%), Gaps = 16/256 (6%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
R+ S+G++ + DAGIY C A NS G N ++ + V ++ +
Sbjct: 659 RMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGD 717
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCV 335
V+ C G P +KW + ++ P + + +P L L I++ + + G++ CV
Sbjct: 718 ITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCV 773
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G AT + + L V P P V + +G L C + P P+ W +
Sbjct: 774 AINEAGRATGK-ITLDVGSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLD 453
+P+ + + + T L I N+ SD G+Y C A N+ G S TTV +
Sbjct: 831 -NMPIFSRPFSVSSISQ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 454 VTSAPDQVVSLTVTNV 469
AP +S +V NV
Sbjct: 886 GLVAPLIGISPSVANV 901
Score = 62.9 bits (146), Expect = 5e-09
Identities = 79/316 (25%), Positives = 125/316 (39%), Gaps = 34/316 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS + +W KDG P+ + + I + G L + + D G YTC A N G +
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVN----IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNP--LLAEH-------IKWERKGYK 302
V++ P + + + + + + I NP L E + W + G+
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 303 IDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ-DVMLIVK--FKPEM 358
+ V P L I +AK E+ G + CV N G + Q DV ++V K
Sbjct: 2818 LTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
P V N + + C PAP +W K+G L + + HK ++
Sbjct: 2876 SDLPEEVTVLVNKSAL--IECLSSGSPAPRNSWQKDGQPLLED-------DHHK--FLSN 2924
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV--VSLTVTNVTHSTVTL 476
+L I N +D G Y C A N G + L+V P + S +T V ++ ++L
Sbjct: 2925 GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 477 EW-VPGFDGGLQSWYR 491
V GF SW +
Sbjct: 2985 TCEVSGFPPPDLSWLK 3000
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 10/183 (5%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
V+ P+F N + I++ G+P T W + G+ I S R +
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP-TIQWNRKGVDIEISH----RIRQL 4399
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
GS L + DAG YTC A N G ++S+++ P I V N +
Sbjct: 4400 GNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKII 4458
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L+C A G P I W R+G+ I N + Y I A+ E+ F+CV N
Sbjct: 4459 LNCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLY--IADAQKEDTSEFECVARNL 4514
Query: 340 IGS 342
+GS
Sbjct: 4515 MGS 4517
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 720 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 774
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 832
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 892
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 893 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 936
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1974
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1975 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 2031
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 2032 ECE-ARGIPAPSLTWLKDGSPVSS 2054
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 2043
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 2101
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 2158
Query: 175 VGIEN 179
+ IE+
Sbjct: 2159 LKIED 2163
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 1799 NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 1857
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 1915
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 1916 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1957
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P AT+TWFK+ + S + IL DN +Y C ATN A E + +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE--MIKHYE 2660
Query: 112 LNVHFAPEAVK-----VRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQN 162
+ V+ P K P +K + TL + A + P A+LSW++DG P+++
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS 2717
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 24 PMITGY-VPG-TTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHS--TTKTTDKAVSAE 79
P + G +P ++ G +L C + G P + W K+ K I S T + A +
Sbjct: 3245 PSVAGAEIPSDVSVLLGENVELVC-NANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 80 ISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLI 139
++I +T + +Y C ATN A E LNV+ P + E + L ++ ++
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEED--RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSIN 3361
Query: 140 CDS-ASSNPPATLSWWRDGIPV 160
+ A+ PP ++W ++G+P+
Sbjct: 3362 IECRATGTPPPQINWLKNGLPL 3383
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C G PL ++TWFK+ + + + + ++ ++ QY C N+A
Sbjct: 2406 LTC-EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPPATLSWWRDGIPVQ 161
E + L+V P V DV +K TL C+ + NP ++W +DG P+Q
Sbjct: 2465 EER--KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE-VTGNPVPEITWHKDGQPLQ 2521
Score = 46.4 bits (105), Expect = 4e-04
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEA 97
GT L C S P +TW+KN + I +T A + I + QY C A
Sbjct: 3074 GTSVSLECESNAVPP-PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 98 TNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
N A + LNV+ P E V TL CD A+ PP T++W ++
Sbjct: 3133 INVAGRDD--KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIPPPTIAWLKNH 3189
Query: 158 IPVQNA 163
++N+
Sbjct: 3190 KRIENS 3195
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 1575
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 1633
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 1634 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Score = 44.4 bits (100), Expect = 0.002
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C TG NP+ +TW K+ + + + + I + +Y C A++ A
Sbjct: 2499 LTCEVTG-NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 103 EIPLFETVTLNVHFAPEAVKVRAE--PDVLKPGIEA--TLICDSASSNPPATLSWWRDGI 158
+ +LNV +P V ++ P+ + + + +L+C+ A S PPAT++W++DG
Sbjct: 2558 HKS--RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCE-AYSYPPATITWFKDGT 2614
Query: 159 PVQN 162
P+++
Sbjct: 2615 PLES 2618
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ L C G P L+W KN++ I T T + I+ + +Y
Sbjct: 2975 TVVVNNFISLTC-EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV----LKPGIEATLICDSASSNPPA 149
C A N A E ++T+ + P ++K + ++ G +L C+S ++ PP
Sbjct: 3034 TCIAINQAGESKKKFSLTV---YVPPSIKDHDSESLSVVNVREGTSVSLECES-NAVPPP 3089
Query: 150 TLSWWRDG 157
++W+++G
Sbjct: 3090 VITWYKNG 3097
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 732
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 733 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 790
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 791 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 838
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 1661 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 1720 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T+ G+ +ACI T G P ++ W ++ + + T + +L T++ +Y
Sbjct: 3446 TVLKGSSTSMACI-TDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKY 3504
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL-ICDSASSNPPATLS 152
C A+N A E+ + L V P + E + + + L + AS P ++
Sbjct: 3505 TCIASNEAGEVS--KHFILKV-LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT 3561
Query: 153 WWRDGIPV 160
W +DG P+
Sbjct: 3562 WMKDGRPL 3569
Score = 39.9 bits (89), Expect = 0.037
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P T+ W + I + + + ++I V ++ Y C ATN A + +
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+TL +P + + V+ G + L C A+ P T++W R G
Sbjct: 4434 LTLQ---SPPIITLEPVETVINAGGKIILNC-QATGEPQPTITWSRQG 4477
Score = 39.5 bits (88), Expect = 0.048
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C +TG P +TW K ++++ + S + I V ++ Y C A N A
Sbjct: 4007 LPCEATG-TPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+ LNV P + + V+ TL C+ A PP ++W +DG
Sbjct: 4066 --TALGKIKLNVQ-VPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDITWHKDG 4116
Score = 39.1 bits (87), Expect = 0.064
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVT 111
P A+L+W+K+ + + S A + I + +Y C A+N A E L
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL--DFD 2759
Query: 112 LNVHFAPEAVKVRAEPDVLKPGIEA-----------TLICDSASSNPPATLSWWRDGIPV 160
+N+ P K+ ++L G +L C++ ++ PP TL+W++DG P+
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPL 2818
Query: 161 QNA 163
++
Sbjct: 2819 TSS 2821
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEIS 81
P I T+ LAC +TG P ++ W KN ++ + S +
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATG-IPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEP-DVLKPGIEATLIC 140
I++ D+ A Y C TN A + TV L V P + EP D L +I
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDK--RTVDLTVQVPP---SIADEPTDFLVTKHAPAVIT 3917
Query: 141 DSASSNPPATLSWWRDGI 158
+AS P ++ W ++GI
Sbjct: 3918 CTASGVPFPSIHWTKNGI 3935
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 889 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 946
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 947 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 1002
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 1003 KASGNPKPSVIWSKKG 1018
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 1090 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C ATN A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 1149 LCVATNIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 1202
Query: 152 SWWRDG 157
+W + G
Sbjct: 1203 TWSKGG 1208
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 1591
Score = 37.1 bits (82), Expect = 0.26
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 48 TGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
T P TLTW+K+ + S+ K + I ++ +Y C A N A E L
Sbjct: 2801 TNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 108 ETVTLNVHFAPEAVKVRAE--PDVLKPGIEATLICDSASSNPPATL-SWWRDGIPV 160
V + V P +K P+ + + + + + SS PA SW +DG P+
Sbjct: 2861 YDVRVLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Score = 37.1 bits (82), Expect = 0.26
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Query: 5 KDSGIFKCMINSPS-DPPSAPMITGYVP----GT------TLAAGTVQKLACISTGGNPL 53
+D+G + C+ +SP+ D ++ +VP GT T+ L C S P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPP- 3650
Query: 54 ATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLN 113
+TW +N +++ +T + + + I + A Y C A+N A + +T+N
Sbjct: 3651 PVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
V P +K + V+ L C A P ++W +DG
Sbjct: 3711 V---PPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITWRKDG 3750
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 1000 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 1058
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 1059 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 1115
Query: 156 D 156
+
Sbjct: 1116 E 1116
Score = 33.1 bits (72), Expect = 4.2
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 610 QAGQASKSATIEMYAPSSYNDTMTGETLSSVSEKSETYSQDDGDERHPPPIPEVPSIHNR 669
QAG++ K ++ +Y P S D E+LS V+ + T + + PP P + N
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKD-HDSESLSVVNVREGTSVSLECESNAVPP-PVITWYKNG 3097
Query: 670 HMLSQTTDAYLMED 683
M++++T ++ D
Sbjct: 3098 RMITESTHVEILAD 3111
>AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin
superfamily, member 9 protein.
Length = 1179
Score = 107 bits (258), Expect = 1e-22
Identities = 99/416 (23%), Positives = 167/416 (40%), Gaps = 26/416 (6%)
Query: 133 GIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP 192
G C ++S+ AT + + V P+ +TV + + ++ A+ P
Sbjct: 199 GSSGVYTCQASSTEGSATHA---TQLLVLGPPVIVVPPKNSTVNASQD-VSLACHAEAYP 254
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ-GAAVA 251
++TY+W +D + + S RI+ +GS L + DAG YTC N A
Sbjct: 255 ANLTYSWFQDNINVFHISRLQPRVRILVDGS-LRLLATQPDDAGCYTCVPSNGLLHPPSA 313
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE 311
+ ++V YPA + ++ V+ C NP L + W + G +
Sbjct: 314 SAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLL-FVSWTKDGKALQLDKFPGW 372
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM-LIVKFKPEMDTSPNFVKSASN 370
+ LII + LG + C N +G+A V +++K P P +
Sbjct: 373 SQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPK-EEYFQE 431
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
VG+ + C + P P +W+K G L A+ N S L++ +
Sbjct: 432 VGRELLIPCSAQGDPPPVVSWTKVGRGLQGQ------AQVDSN------SSLILRPLTKE 479
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWY 490
+G +EC A N + T+ + V VV+ + W PGFDGG +
Sbjct: 480 AHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGGYLQRF 539
Query: 491 RIRYRKVF--DDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ Y + D ++ V +P A + V GL+ +T Y FSV+A NK+G +
Sbjct: 540 SVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPF 595
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/249 (22%), Positives = 109/249 (43%), Gaps = 16/249 (6%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V + P F +T E EP+ + A G+P P +T W G + Q G
Sbjct: 130 LTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVT--WKLRGKDLGQ-----GQG 182
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
++ + L + ++ R +G+YTC+A +++G+A + V P I +N N ++
Sbjct: 183 QVQVQNGTLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQ 242
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPK---NLTSYLIIRKAKSENLGNFQ 333
D L+C A P + W + + S +P+ + L + + ++ G +
Sbjct: 243 DVSLACHAEAYPANLTY-SWFQDNINVFHIS-RLQPRVRILVDGSLRLLATQPDDAGCYT 300
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF-TWS 392
CV +NG+ L V + ++ P ++ +G G + C ++ P F +W+
Sbjct: 301 CVPSNGLLHPPSASAYLTVLYPAQVTAMP--PETPLPIGMPGVIRCPVRANPPLLFVSWT 358
Query: 393 KNGVKLPVN 401
K+G L ++
Sbjct: 359 KDGKALQLD 367
Score = 40.7 bits (91), Expect = 0.021
Identities = 45/178 (25%), Positives = 66/178 (37%), Gaps = 14/178 (7%)
Query: 6 DSGIFKCM-INSPSDPPSAP---------MITGYVPGTTLAAGTVQKLACISTGGNPLAT 55
D+G + C+ N PPSA +T P T L G + C PL
Sbjct: 295 DAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLF 354
Query: 56 LTWFKNDKKIH-STTKTTDKAVSAEISILTNVTDNQAQYRCEATNS-ATEIPLFETVTLN 113
++W K+ K + + + I D +Y C NS T P VT
Sbjct: 355 VSWTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGP--SPVTRV 412
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTS 171
+ AP A R + + + LI SA +PP +SW + G +Q D +S
Sbjct: 413 LLKAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSS 470
>AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein.
Length = 1189
Score = 107 bits (258), Expect = 1e-22
Identities = 99/416 (23%), Positives = 167/416 (40%), Gaps = 26/416 (6%)
Query: 133 GIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP 192
G C ++S+ AT + + V P+ +TV + + ++ A+ P
Sbjct: 209 GSSGVYTCQASSTEGSATHA---TQLLVLGPPVIVVPPKNSTVNASQD-VSLACHAEAYP 264
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ-GAAVA 251
++TY+W +D + + S RI+ +GS L + DAG YTC N A
Sbjct: 265 ANLTYSWFQDNINVFHISRLQPRVRILVDGS-LRLLATQPDDAGCYTCVPSNGLLHPPSA 323
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE 311
+ ++V YPA + ++ V+ C NP L + W + G +
Sbjct: 324 SAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLL-FVSWTKDGKALQLDKFPGW 382
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM-LIVKFKPEMDTSPNFVKSASN 370
+ LII + LG + C N +G+A V +++K P P +
Sbjct: 383 SQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPK-EEYFQE 441
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
VG+ + C + P P +W+K G L A+ N S L++ +
Sbjct: 442 VGRELLIPCSAQGDPPPVVSWTKVGRGLQGQ------AQVDSN------SSLILRPLTKE 489
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWY 490
+G +EC A N + T+ + V VV+ + W PGFDGG +
Sbjct: 490 AHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGGYLQRF 549
Query: 491 RIRYRKVF--DDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ Y + D ++ V +P A + V GL+ +T Y FSV+A NK+G +
Sbjct: 550 SVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPF 605
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/249 (22%), Positives = 109/249 (43%), Gaps = 16/249 (6%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V + P F +T E EP+ + A G+P P +T W G + Q G
Sbjct: 140 LTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVT--WKLRGKDLGQ-----GQG 192
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
++ + L + ++ R +G+YTC+A +++G+A + V P I +N N ++
Sbjct: 193 QVQVQNGTLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQ 252
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPK---NLTSYLIIRKAKSENLGNFQ 333
D L+C A P + W + + S +P+ + L + + ++ G +
Sbjct: 253 DVSLACHAEAYPANLTY-SWFQDNINVFHIS-RLQPRVRILVDGSLRLLATQPDDAGCYT 310
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF-TWS 392
CV +NG+ L V + ++ P ++ +G G + C ++ P F +W+
Sbjct: 311 CVPSNGLLHPPSASAYLTVLYPAQVTAMP--PETPLPIGMPGVIRCPVRANPPLLFVSWT 368
Query: 393 KNGVKLPVN 401
K+G L ++
Sbjct: 369 KDGKALQLD 377
Score = 40.7 bits (91), Expect = 0.021
Identities = 45/178 (25%), Positives = 66/178 (37%), Gaps = 14/178 (7%)
Query: 6 DSGIFKCM-INSPSDPPSAP---------MITGYVPGTTLAAGTVQKLACISTGGNPLAT 55
D+G + C+ N PPSA +T P T L G + C PL
Sbjct: 305 DAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLF 364
Query: 56 LTWFKNDKKIH-STTKTTDKAVSAEISILTNVTDNQAQYRCEATNS-ATEIPLFETVTLN 113
++W K+ K + + + I D +Y C NS T P VT
Sbjct: 365 VSWTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGP--SPVTRV 422
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTS 171
+ AP A R + + + LI SA +PP +SW + G +Q D +S
Sbjct: 423 LLKAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSS 480
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens cDNA
FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 104 bits (249), Expect = 2e-21
Identities = 90/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V P + V ++ +P+ + A+G P PSIT W KD P+ + GN
Sbjct: 891 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSIT--WLKDDQPVNTAQ---GNL 945
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVANP 274
+I S G +L + K DAG YTC A N+ G +I + VH P ++ + N
Sbjct: 946 KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLV 1005
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
+ L C A GNP+ I W + + S+TF N + I A+ + G ++
Sbjct: 1006 SNPVQLECKAAGNPVPV--ITWYKDNRLLSGSTSMTF--LNRGQIIDIESAQISDAGIYK 1061
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
CV N G AT+ L V P + S N V A V RL C+ + +PAPS TW K
Sbjct: 1062 CVAINSAG-ATELFYSLQVHVAPSISGSNNMV--AVVVNNPVRLECEARGIPAPSLTWLK 1118
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+G PV++ + ++ +L + + SD G Y C A N G + L
Sbjct: 1119 DG--SPVSSFSNGL------QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 1170
Query: 454 VTSAPD 459
V P+
Sbjct: 1171 VYVPPN 1176
Score = 92.7 bits (220), Expect = 5e-18
Identities = 80/293 (27%), Positives = 120/293 (40%), Gaps = 21/293 (7%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNM 227
D TSY V + N L + G+PP T W KDG + + +I+ G L +
Sbjct: 810 DETSYFIVMVNNL-LELDCHVTGSPPP-TIMWLKDGQLVDERD----GFKILLNGRKLVI 863
Query: 228 TKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPNEDAVLSCTAI 285
+ + G+Y C A N+ G V+VH P IKS +S+ VV + L C A
Sbjct: 864 AQAQVSNTGLYRCMAANTAGDHKEEFEVTVHVPPTIKSSGLSERVVVK-YKPVALQCIAN 922
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
G P I W + ++ + ++ L I K E+ G + CV N G T+
Sbjct: 923 GIP--NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE-TQ 979
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
Q + L V P ++ + + V +L CK P P TW K+ L +TS
Sbjct: 980 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1039
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + ++ I + SD G Y+C A N G + L V AP
Sbjct: 1040 F---------LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 1083
Score = 89.8 bits (213), Expect = 3e-17
Identities = 76/286 (26%), Positives = 118/286 (41%), Gaps = 20/286 (6%)
Query: 160 VQNAPIFDDTTSY-NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
V P +D N + + P+ + +A GNP + TW KD ++ S+ +
Sbjct: 986 VHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVI-TWYKDNRLLSGSTSMT----F 1040
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
++ G ++++ DAGIY C A+NS GA S+ VH I + V N
Sbjct: 1041 LNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 1100
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A G P A + W + G + S + + L + A+ + G + CV N
Sbjct: 1101 RLECEARGIP--APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 1158
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G ++D+ L V P + V + Q L+C+ ++P P+ TW K+G L
Sbjct: 1159 AAGE-KQRDIDLRVYVPPNIMGEEQNVSVL--ISQAVELLCQSDAIPPPTLTWLKDGHPL 1215
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
K +N SVL I + D G Y C A N G
Sbjct: 1216 ----LKKPGLSISEN-----RSVLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 82.2 bits (194), Expect = 7e-15
Identities = 89/343 (25%), Positives = 133/343 (38%), Gaps = 28/343 (8%)
Query: 160 VQNAPIFDDTTS-YNTV---GIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGN 215
VQ P +D YNT + N+ + A G P T W +G +T
Sbjct: 329 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKP-TIKWLHNGRELTGREPGIS- 386
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ--NVVAN 273
I+ +G++L + +T +D G Y C AVN G ++ VH P IK Q NV
Sbjct: 387 --ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVL 444
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N+ L C G P + I W + ++ +S T + N L + +A E+ G +
Sbjct: 445 LNQLTNLFCEVEGTP--SPIIMWYKDNVQV-TESSTIQTVNNGRILKLFRATPEDAGRYS 501
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV-GQVGRLMCKCKSVPAPSFTWS 392
C N G T Q I P NF S V + L C+ K P P W
Sbjct: 502 CKAINIAG--TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 559
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+G L F + + VL + N +D G Y+C N G +KL
Sbjct: 560 KDGKPL--------FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 611
Query: 453 DVTSAPD---QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ P V+ ++ + +S + LE G +WY+
Sbjct: 612 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK 654
Score = 79.0 bits (186), Expect = 6e-14
Identities = 86/317 (27%), Positives = 127/317 (40%), Gaps = 26/317 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
L + +A GNP I TW KDG+P+ ++ N RI + G L + D G Y C
Sbjct: 730 LTLECKAAGNPSPIL-TWLKDGVPVK----ANDNIRIEAGGKKLEIMSAQEIDRGQYICV 784
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQN--VVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
A + G V V P I+ + + N L C G+P I W +
Sbjct: 785 ATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKD 842
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
G +D + F+ L+I +A+ N G ++C+ N G K++ + V P +
Sbjct: 843 GQLVDERD-GFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD-HKEEFEVTVHVPPTIK 900
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+S + V L C +P PS TW K+ PVNT+ N I +
Sbjct: 901 SSGLSERVVVKYKPVA-LQCIANGIPNPSITWLKD--DQPVNTA-------QGNLKIQSS 950
Query: 420 S-VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP---DQVVSLTVTNVTHSTVT 475
VL I D G Y C A N G + ++L V P D L T + + V
Sbjct: 951 GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQ 1010
Query: 476 LEW-VPGFDGGLQSWYR 491
LE G + +WY+
Sbjct: 1011 LECKAAGNPVPVITWYK 1027
Score = 77.4 bits (182), Expect = 2e-13
Identities = 71/245 (28%), Positives = 99/245 (40%), Gaps = 20/245 (8%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
S+GS L++ ++ D G YTC A N G SV VH I+ Q +
Sbjct: 12 SDGS-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVT 70
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
L C A GNP + W +KG I S F S ++ E+ G + C N
Sbjct: 71 LPCKASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNT 127
Query: 340 IGSATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
G A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 128 AGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK 186
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
T+ + F + + I TSD G Y C A N G T VKL+
Sbjct: 187 ---------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAINIAGNVTQAVKLN 237
Query: 454 VTSAP 458
V P
Sbjct: 238 VHVPP 242
Score = 73.7 bits (173), Expect = 2e-12
Identities = 80/308 (25%), Positives = 121/308 (39%), Gaps = 27/308 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
I V P T N V + N + + + G P P I W KDG P+ N
Sbjct: 517 IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLF---LGDPN 571
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK--SVSQNVVAN 273
++ G +L++ R+D G Y C N+ G +I ++++ P IK +V+ ++
Sbjct: 572 VELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVL 631
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
N L C G P+ A I W + G I S YL I +A+ + +
Sbjct: 632 INSLIKLECETRGLPMPA--ITWYKDGQPIMSSSQALYIDK-GQYLHIPRAQVSDSATYT 688
Query: 334 CVVNNGIGSATKQ---DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C V N G+A K DV + + + T N + L CK P+P T
Sbjct: 689 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLN---KQVVIAHSLTLECKAAGNPSPILT 745
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W K+GV + N + + A K L I + D G Y C A + G
Sbjct: 746 WLKDGVPVKANDNIRIEAGGKK---------LEIMSAQEIDRGQYICVATSVAGEKEIKY 796
Query: 451 KLDVTSAP 458
++DV P
Sbjct: 797 EVDVLVPP 804
Score = 70.1 bits (164), Expect = 3e-11
Identities = 77/299 (25%), Positives = 118/299 (39%), Gaps = 24/299 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 163 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 217
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A+N G + ++VH P I+ +++ + + C A G PL I W
Sbjct: 218 MYLCVAINIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPV--ITW 275
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ G +D + P S I +A + G + CV N I + ++ L V+
Sbjct: 276 SKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGIYTCVATN-IAGTDETEITLHVQE 331
Query: 355 KPEM-DTSP--NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
P + D P N Q C K P P+ W NG +L T +
Sbjct: 332 PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL---TGREPGISIL 388
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
++ ++L+I +V D G Y C A NE G + L V P VTNV+
Sbjct: 389 EDG-----TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 442
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + T L + VQ L C GNP+ +TW+K+++ + +T T
Sbjct: 988 EPPSLEDAGKMLNETVLVSNPVQ-LEC-KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ 1045
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
I I + + Y+C A NSA LF +L VH AP ++ + L
Sbjct: 1046 IIDIESAQISDAGIYKCVAINSAGATELF--YSLQVHVAP-SISGSNNMVAVVVNNPVRL 1102
Query: 139 ICDSASSNPPATLSWWRDGIPVQN 162
C+ A P +L+W +DG PV +
Sbjct: 1103 ECE-ARGIPAPSLTWLKDGSPVSS 1125
Score = 53.2 bits (122), Expect = 4e-06
Identities = 50/185 (27%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 6 DSGIFKCM-INSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
D+GI+KC+ INS AP I+G + +L C G P +L
Sbjct: 1056 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPAPSL 1114
Query: 57 TWFKNDKKIHSTTKTTDKAVSAEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVH 115
TW K+ + S + I LT+ + +Y C A N+A E + L V+
Sbjct: 1115 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ--RDIDLRVY 1172
Query: 116 FAPEAVKVRAEPDVL-KPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT 174
P + VL +E L+C S + PP TL+W +DG P+ P + + +
Sbjct: 1173 VPPNIMGEEQNVSVLISQAVE--LLCQS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV 1229
Query: 175 VGIEN 179
+ IE+
Sbjct: 1230 LKIED 1234
Score = 52.0 bits (119), Expect = 8e-06
Identities = 42/165 (25%), Positives = 82/165 (49%), Gaps = 20/165 (12%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGTTLAAGTVQK---------LACISTGGNPLAT 55
++G+++CM N+ D +T +VP T ++G ++ L CI+ G P +
Sbjct: 870 NTGLYRCMAANTAGDHKEEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANG-IPNPS 928
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEI-SILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW K+D+ +++ S + I + ++ +Y C ATN+A E + + L+V
Sbjct: 929 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ--QHIQLHV 986
Query: 115 HFAP---EAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
H P +A K+ E ++ ++ L C A+ NP ++W++D
Sbjct: 987 HEPPSLEDAGKMLNETVLVSNPVQ--LEC-KAAGNPVPVITWYKD 1028
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%)
Query: 4 KKDSGIFKCMINSPSDPPSAPM-ITGYVPGT----------TLAAGTVQKLACISTGGNP 52
+ D G ++C +++ + + + +T Y+P + ++ ++ KL C T G P
Sbjct: 588 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC-ETRGLP 646
Query: 53 LATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTL 112
+ +TW+K+ + I S+++ + I + A Y C N A ++ +
Sbjct: 647 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE--KSFHV 704
Query: 113 NVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPVQ 161
+V+ P A P + I +L + A+ NP L+W +DG+PV+
Sbjct: 705 DVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 754
Score = 41.5 bits (93), Expect = 0.012
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP LTW K+ + + +A ++ I++ ++ QY C AT+ A
Sbjct: 732 LEC-KAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 790
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDG 157
E + V + V P A++ E + L D + +PP T+ W +DG
Sbjct: 791 EKEIKYEVDVLV---PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG 843
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN-QAQYRCEATNSATEIPLFE 108
G P + WFK+ K + + ++ L N N + +Y+C +N+A +
Sbjct: 550 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 609
Query: 109 TVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
+T+ + + + V + VL + L C++ PA ++W++DG P+ ++
Sbjct: 610 KLTIYIPPSIKGGNVTTDISVLINSL-IKLECETRGLPMPA-ITWYKDGQPIMSS 662
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 71 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 129
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 130 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 186
Query: 156 D 156
+
Sbjct: 187 E 187
Score = 35.1 bits (77), Expect = 1.0
Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 9/126 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
++ AG L C P +TW K + I + S + I T + Y
Sbjct: 161 SVLAGEEVTLPC-EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 219
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK--PGIEATLICDSASSNPPATL 151
C A N A + + V LNVH P K++ P LK G + C +A P +
Sbjct: 220 LCVAINIAGNVT--QAVKLNVHVPP---KIQRGPKHLKVQVGQRVDIPC-NAQGTPLPVI 273
Query: 152 SWWRDG 157
+W + G
Sbjct: 274 TWSKGG 279
>AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens
cDNA FLJ40259 fis, clone TESTI2025486. ).
Length = 600
Score = 103 bits (247), Expect = 3e-21
Identities = 91/385 (23%), Positives = 160/385 (41%), Gaps = 19/385 (4%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRII 219
VQ P TV I + L+ + RA+ P ++TYTW + + RI+
Sbjct: 67 VQGPPFIVSPPENITVNISQDALL-TCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRIL 125
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV-ANISVSVHYPAGIKSVSQNVVANPNEDA 278
+G+++ + ++ D+G YTC NS G + A+ ++V YPA + ++ +
Sbjct: 126 IDGTLI-IFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHG 184
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
+ C P A +KW + G + + + I +A E LG + CV N
Sbjct: 185 YIRCPVDAEPP-ATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYN 243
Query: 339 GIGSATKQ-DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
+G+ + L++K P P + + G+ + C P P TW K G
Sbjct: 244 TLGTMGQSAPARLVLKDPPYFTVLPGW-EYRQEAGRELLIPCAAAGDPFPVITWRKVGKP 302
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
+ +K+ A + L ++ D+G +EC A N + T + L V
Sbjct: 303 ----SRSKHSA--------LPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGT 350
Query: 458 PDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDV-LPKHATNFT 516
V+ +T + W PG+DGG + + + ++ + + + +P +
Sbjct: 351 SPHAPGSVRVQVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLPVPPGPSWLL 410
Query: 517 VHGLEKNTDYIFSVMAINKIGQSKY 541
V LE T Y FSV+A NK+G S +
Sbjct: 411 VDTLEPETAYQFSVLAQNKLGTSVF 435
Score = 80.2 bits (189), Expect = 3e-14
Identities = 65/215 (30%), Positives = 99/215 (46%), Gaps = 11/215 (5%)
Query: 188 ADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG 247
A GNP I TW K+G + +SG ++ S+GS L +T ++R D G YTC A + QG
Sbjct: 5 AFGNPKPIV-TWLKEGTLLG----ASGKYQV-SDGS-LTVTSVSREDRGAYTCRAYSIQG 57
Query: 248 AAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP-LLAEHIKWERKGYKIDPK 306
AV + V P I S +N+ N ++DA+L+C A P L W+ +
Sbjct: 58 EAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQND 117
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
+ LII + K E+ G + CV +N +G + L V++ + P +
Sbjct: 118 LKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIY 177
Query: 367 SASNVGQVGRLMCKCKS-VPAPSFTWSKNGVKLPV 400
VG G + C + PA W+K+G L V
Sbjct: 178 VP--VGIHGYIRCPVDAEPPATVVKWNKDGRPLQV 210
Score = 58.8 bits (136), Expect = 7e-08
Identities = 100/449 (22%), Positives = 162/449 (36%), Gaps = 38/449 (8%)
Query: 172 YNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT 231
Y VGI I D PP+ W KDG P+ Q + G ++ +GS + + + T
Sbjct: 177 YVPVGIHG---YIRCPVDAEPPATVVKWNKDGRPL-QVEKNLGWT-LMEDGS-IRIEEAT 230
Query: 232 RHDAGIYTCEAVNSQG----AAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGN 287
G YTC N+ G +A A + V P + ++ C A G+
Sbjct: 231 EEALGTYTCVPYNTLGTMGQSAPARL-VLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGD 289
Query: 288 PLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQD 347
P I W + G K +L R E+ G ++CV N + S T
Sbjct: 290 PFPV--ITWRKVGKPSRSKHSALPSGSLQ----FRALSKEDHGEWECVATNVVTSITAST 343
Query: 348 VMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG-------VKLPV 400
+ ++ P S V+ + V W K + LPV
Sbjct: 344 HLTVIGTSPHAPGSVR-VQVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLPV 402
Query: 401 NTSTKYFAEFHKNDHITYT-SVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
+ Y SVL N + TS + E N L F TT + V P
Sbjct: 403 PPGPSWLLVDTLEPETAYQFSVLAQNKLGTSVFS--EVVTVNTLAFPITTPEPLVLVTPP 460
Query: 460 QVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHG 519
+ + + N T V L W+P + I +V + +D +P F
Sbjct: 461 RCL---IANRTQQGVLLSWLPPANHSFPIDRYIMEFRVAERWELLDDGIPGTEGEFFAKD 517
Query: 520 LEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVIVY 579
L ++T Y F +A+ + + ++S+++ ++ + + P ++ V
Sbjct: 518 LSQDTWYEFRALAV----MQDLISEPSNIAGVSSTDIFPQPDLTEDGLARPVLAGIVATI 573
Query: 580 VSLTGAVLVLINVALIACFVWKRRLRRIK 608
L A+L L ACFV K+R R++K
Sbjct: 574 CFLAAAILFS---TLAACFVNKQRKRKLK 599
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16
to 1881) protein.
Length = 1897
Score = 99.5 bits (237), Expect = 4e-20
Identities = 99/365 (27%), Positives = 155/365 (42%), Gaps = 35/365 (9%)
Query: 187 RADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRHDAGIYTCEAVN 244
+A G P P IT W K G ++ + + GS+L + L + D IY C A N
Sbjct: 45 QATGEPKPRIT--WMKKGKKVSSQRFEV-IEFDDGAGSVLRIQPLRVQRDEAIYECTATN 101
Query: 245 SQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
S G + +SV P G S+ Q V A + C A GNP I W
Sbjct: 102 SLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNP--DPEISWF 159
Query: 298 RKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK- 355
+ +DP + K L S L I ++ + G ++CV N G+ L V+ +
Sbjct: 160 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRR 219
Query: 356 --PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKN 413
P P+ + G V L C P P W +L TK ++
Sbjct: 220 VAPRFSIPPSSQEVMPG-GSVN-LTCVAVGAPMPYVKWMMGAEEL-----TK------ED 266
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ +VL ++NV S +Y C A + LG T ++ V + P + L VT T ++
Sbjct: 267 EMPVGRNVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATS 324
Query: 474 VTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAI 533
VTL W G + ++Y I+YR + +++V T +++ GL ++Y F V+A+
Sbjct: 325 VTLTWDSG-NSEPVTYYGIQYRAAGTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAV 382
Query: 534 NKIGQ 538
N IG+
Sbjct: 383 NSIGR 387
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/150 (28%), Positives = 64/150 (42%), Gaps = 10/150 (6%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
S P+ T +G V C +TG P +TW K KK+ S + S
Sbjct: 21 SKPVFIKVPEDQTGLSGGVASFVCQATG-EPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 79
Query: 82 ILT----NVTDNQAQYRCEATNSATEIPLFETVTL--NVHFAPEAVKVRAEPD--VLKPG 133
+L V ++A Y C ATNS EI +++ P + P V++
Sbjct: 80 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 139
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQNA 163
AT++C +A NP +SW++D +PV A
Sbjct: 140 RTATMLC-AAGGNPDPEISWFKDFLPVDPA 168
Score = 44.0 bits (99), Expect = 0.002
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFD-G 484
+V + Y + GAR++ TTT V P ++S T N T L+W P +
Sbjct: 784 SVTVAAYTTKGDGARSKPKIVTTTGA--VPGRPTMMISTTAMN----TALLQWHPPKELP 837
Query: 485 GLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG-----QS 539
G YR++Y + D++ K +FTV GL K T YIF + A N+ G +
Sbjct: 838 GELLGYRLQYCRA-DEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEK 896
Query: 540 KYR-PDDTKATTLTSSEVGELSTVSTEYVETPDI 572
+ R P+D + + V L+T +TE P +
Sbjct: 897 EIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 930
Score = 41.1 bits (92), Expect = 0.016
Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 11/101 (10%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D+ P F+K + G V +C+ P P TW K G K+ S++ F +D
Sbjct: 20 DSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV----SSQRFEVIEFDD 75
Query: 415 HITYTSVLLINNVATS-DYGSYECGARNELGFSTTTVKLDV 454
SVL I + D YEC A N LG T+ KL V
Sbjct: 76 GA--GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV 114
Score = 37.1 bits (82), Expect = 0.26
Identities = 30/132 (22%), Positives = 49/132 (37%), Gaps = 4/132 (3%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKT--TDKAVS 77
PP P I + + C + GGNP ++WFK+ + T + S
Sbjct: 121 PPGFPSIDMGPQLKVVEKARTATMLC-AAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 179
Query: 78 AEISILTNVTDNQAQYRCEATNSA-TEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEA 136
+ I ++ +Q +Y C ATNSA T + + V + + PG
Sbjct: 180 GALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSV 239
Query: 137 TLICDSASSNPP 148
L C + + P
Sbjct: 240 NLTCVAVGAPMP 251
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 99.5 bits (237), Expect = 4e-20
Identities = 99/365 (27%), Positives = 155/365 (42%), Gaps = 35/365 (9%)
Query: 187 RADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRHDAGIYTCEAVN 244
+A G P P IT W K G ++ + + GS+L + L + D IY C A N
Sbjct: 55 QATGEPKPRIT--WMKKGKKVSSQRFEV-IEFDDGAGSVLRIQPLRVQRDEAIYECTATN 111
Query: 245 SQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
S G + +SV P G S+ Q V A + C A GNP I W
Sbjct: 112 SLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNP--DPEISWF 169
Query: 298 RKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK- 355
+ +DP + K L S L I ++ + G ++CV N G+ L V+ +
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRR 229
Query: 356 --PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKN 413
P P+ + G V L C P P W +L TK ++
Sbjct: 230 VAPRFSIPPSSQEVMPG-GSVN-LTCVAVGAPMPYVKWMMGAEEL-----TK------ED 276
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ +VL ++NV S +Y C A + LG T ++ V + P + L VT T ++
Sbjct: 277 EMPVGRNVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATS 334
Query: 474 VTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAI 533
VTL W G + ++Y I+YR + +++V T +++ GL ++Y F V+A+
Sbjct: 335 VTLTWDSG-NSEPVTYYGIQYRAAGTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAV 392
Query: 534 NKIGQ 538
N IG+
Sbjct: 393 NSIGR 397
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/150 (28%), Positives = 64/150 (42%), Gaps = 10/150 (6%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
S P+ T +G V C +TG P +TW K KK+ S + S
Sbjct: 31 SKPVFIKVPEDQTGLSGGVASFVCQATG-EPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 89
Query: 82 ILT----NVTDNQAQYRCEATNSATEIPLFETVTL--NVHFAPEAVKVRAEPD--VLKPG 133
+L V ++A Y C ATNS EI +++ P + P V++
Sbjct: 90 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQNA 163
AT++C +A NP +SW++D +PV A
Sbjct: 150 RTATMLC-AAGGNPDPEISWFKDFLPVDPA 178
Score = 44.0 bits (99), Expect = 0.002
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFD-G 484
+V + Y + GAR++ TTT V P ++S T N T L+W P +
Sbjct: 785 SVTVAAYTTKGDGARSKPKIVTTTGA--VPGRPTMMISTTAMN----TALLQWHPPKELP 838
Query: 485 GLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG-----QS 539
G YR++Y + D++ K +FTV GL K T YIF + A N+ G +
Sbjct: 839 GELLGYRLQYCRA-DEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEK 897
Query: 540 KYR-PDDTKATTLTSSEVGELSTVSTEYVETPDI 572
+ R P+D + + V L+T +TE P +
Sbjct: 898 EIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 931
Score = 41.1 bits (92), Expect = 0.016
Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 11/101 (10%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D+ P F+K + G V +C+ P P TW K G K+ S++ F +D
Sbjct: 30 DSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV----SSQRFEVIEFDD 85
Query: 415 HITYTSVLLINNVATS-DYGSYECGARNELGFSTTTVKLDV 454
SVL I + D YEC A N LG T+ KL V
Sbjct: 86 GA--GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV 124
Score = 37.1 bits (82), Expect = 0.26
Identities = 30/132 (22%), Positives = 49/132 (37%), Gaps = 4/132 (3%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKT--TDKAVS 77
PP P I + + C + GGNP ++WFK+ + T + S
Sbjct: 131 PPGFPSIDMGPQLKVVEKARTATMLC-AAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 189
Query: 78 AEISILTNVTDNQAQYRCEATNSA-TEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEA 136
+ I ++ +Q +Y C ATNSA T + + V + + PG
Sbjct: 190 GALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSV 249
Query: 137 TLICDSASSNPP 148
L C + + P
Sbjct: 250 NLTCVAVGAPMP 261
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 99.5 bits (237), Expect = 4e-20
Identities = 99/365 (27%), Positives = 155/365 (42%), Gaps = 35/365 (9%)
Query: 187 RADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRHDAGIYTCEAVN 244
+A G P P IT W K G ++ + + GS+L + L + D IY C A N
Sbjct: 55 QATGEPKPRIT--WMKKGKKVSSQRFEV-IEFDDGAGSVLRIQPLRVQRDEAIYECTATN 111
Query: 245 SQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
S G + +SV P G S+ Q V A + C A GNP I W
Sbjct: 112 SLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNP--DPEISWF 169
Query: 298 RKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK- 355
+ +DP + K L S L I ++ + G ++CV N G+ L V+ +
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRR 229
Query: 356 --PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKN 413
P P+ + G V L C P P W +L TK ++
Sbjct: 230 VAPRFSIPPSSQEVMPG-GSVN-LTCVAVGAPMPYVKWMMGAEEL-----TK------ED 276
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ +VL ++NV S +Y C A + LG T ++ V + P + L VT T ++
Sbjct: 277 EMPVGRNVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATS 334
Query: 474 VTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAI 533
VTL W G + ++Y I+YR + +++V T +++ GL ++Y F V+A+
Sbjct: 335 VTLTWDSG-NSEPVTYYGIQYRAAGTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAV 392
Query: 534 NKIGQ 538
N IG+
Sbjct: 393 NSIGR 397
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/150 (28%), Positives = 64/150 (42%), Gaps = 10/150 (6%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
S P+ T +G V C +TG P +TW K KK+ S + S
Sbjct: 31 SKPVFIKVPEDQTGLSGGVASFVCQATG-EPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 89
Query: 82 ILT----NVTDNQAQYRCEATNSATEIPLFETVTL--NVHFAPEAVKVRAEPD--VLKPG 133
+L V ++A Y C ATNS EI +++ P + P V++
Sbjct: 90 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQNA 163
AT++C +A NP +SW++D +PV A
Sbjct: 150 RTATMLC-AAGGNPDPEISWFKDFLPVDPA 178
Score = 44.0 bits (99), Expect = 0.002
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFD-G 484
+V + Y + GAR++ TTT V P ++S T N T L+W P +
Sbjct: 794 SVTVAAYTTKGDGARSKPKIVTTTGA--VPGRPTMMISTTAMN----TALLQWHPPKELP 847
Query: 485 GLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG-----QS 539
G YR++Y + D++ K +FTV GL K T YIF + A N+ G +
Sbjct: 848 GELLGYRLQYCRA-DEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEK 906
Query: 540 KYR-PDDTKATTLTSSEVGELSTVSTEYVETPDI 572
+ R P+D + + V L+T +TE P +
Sbjct: 907 EIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 940
Score = 41.1 bits (92), Expect = 0.016
Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 11/101 (10%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D+ P F+K + G V +C+ P P TW K G K+ S++ F +D
Sbjct: 30 DSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV----SSQRFEVIEFDD 85
Query: 415 HITYTSVLLINNVATS-DYGSYECGARNELGFSTTTVKLDV 454
SVL I + D YEC A N LG T+ KL V
Sbjct: 86 GA--GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV 124
Score = 37.1 bits (82), Expect = 0.26
Identities = 30/132 (22%), Positives = 49/132 (37%), Gaps = 4/132 (3%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKT--TDKAVS 77
PP P I + + C + GGNP ++WFK+ + T + S
Sbjct: 131 PPGFPSIDMGPQLKVVEKARTATMLC-AAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 189
Query: 78 AEISILTNVTDNQAQYRCEATNSA-TEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEA 136
+ I ++ +Q +Y C ATNSA T + + V + + PG
Sbjct: 190 GALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSV 249
Query: 137 TLICDSASSNPP 148
L C + + P
Sbjct: 250 NLTCVAVGAPMP 261
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 99.5 bits (237), Expect = 4e-20
Identities = 99/365 (27%), Positives = 155/365 (42%), Gaps = 35/365 (9%)
Query: 187 RADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRHDAGIYTCEAVN 244
+A G P P IT W K G ++ + + GS+L + L + D IY C A N
Sbjct: 55 QATGEPKPRIT--WMKKGKKVSSQRFEV-IEFDDGAGSVLRIQPLRVQRDEAIYECTATN 111
Query: 245 SQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
S G + +SV P G S+ Q V A + C A GNP I W
Sbjct: 112 SLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNP--DPEISWF 169
Query: 298 RKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK- 355
+ +DP + K L S L I ++ + G ++CV N G+ L V+ +
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRR 229
Query: 356 --PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKN 413
P P+ + G V L C P P W +L TK ++
Sbjct: 230 VAPRFSIPPSSQEVMPG-GSVN-LTCVAVGAPMPYVKWMMGAEEL-----TK------ED 276
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ +VL ++NV S +Y C A + LG T ++ V + P + L VT T ++
Sbjct: 277 EMPVGRNVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATS 334
Query: 474 VTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAI 533
VTL W G + ++Y I+YR + +++V T +++ GL ++Y F V+A+
Sbjct: 335 VTLTWDSG-NSEPVTYYGIQYRAAGTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAV 392
Query: 534 NKIGQ 538
N IG+
Sbjct: 393 NSIGR 397
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/150 (28%), Positives = 64/150 (42%), Gaps = 10/150 (6%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
S P+ T +G V C +TG P +TW K KK+ S + S
Sbjct: 31 SKPVFIKVPEDQTGLSGGVASFVCQATG-EPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 89
Query: 82 ILT----NVTDNQAQYRCEATNSATEIPLFETVTL--NVHFAPEAVKVRAEPD--VLKPG 133
+L V ++A Y C ATNS EI +++ P + P V++
Sbjct: 90 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQNA 163
AT++C +A NP +SW++D +PV A
Sbjct: 150 RTATMLC-AAGGNPDPEISWFKDFLPVDPA 178
Score = 44.0 bits (99), Expect = 0.002
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFD-G 484
+V + Y + GAR++ TTT V P ++S T N T L+W P +
Sbjct: 785 SVTVAAYTTKGDGARSKPKIVTTTGA--VPGRPTMMISTTAMN----TALLQWHPPKELP 838
Query: 485 GLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG-----QS 539
G YR++Y + D++ K +FTV GL K T YIF + A N+ G +
Sbjct: 839 GELLGYRLQYCRA-DEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEK 897
Query: 540 KYR-PDDTKATTLTSSEVGELSTVSTEYVETPDI 572
+ R P+D + + V L+T +TE P +
Sbjct: 898 EIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 931
Score = 41.1 bits (92), Expect = 0.016
Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 11/101 (10%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D+ P F+K + G V +C+ P P TW K G K+ S++ F +D
Sbjct: 30 DSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV----SSQRFEVIEFDD 85
Query: 415 HITYTSVLLINNVATS-DYGSYECGARNELGFSTTTVKLDV 454
SVL I + D YEC A N LG T+ KL V
Sbjct: 86 GA--GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV 124
Score = 37.1 bits (82), Expect = 0.26
Identities = 30/132 (22%), Positives = 49/132 (37%), Gaps = 4/132 (3%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKT--TDKAVS 77
PP P I + + C + GGNP ++WFK+ + T + S
Sbjct: 131 PPGFPSIDMGPQLKVVEKARTATMLC-AAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 189
Query: 78 AEISILTNVTDNQAQYRCEATNSA-TEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEA 136
+ I ++ +Q +Y C ATNSA T + + V + + PG
Sbjct: 190 GALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSV 249
Query: 137 TLICDSASSNPP 148
L C + + P
Sbjct: 250 NLTCVAVGAPMP 261
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 99.5 bits (237), Expect = 4e-20
Identities = 99/365 (27%), Positives = 155/365 (42%), Gaps = 35/365 (9%)
Query: 187 RADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRHDAGIYTCEAVN 244
+A G P P IT W K G ++ + + GS+L + L + D IY C A N
Sbjct: 75 QATGEPKPRIT--WMKKGKKVSSQRFEV-IEFDDGAGSVLRIQPLRVQRDEAIYECTATN 131
Query: 245 SQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
S G + +SV P G S+ Q V A + C A GNP I W
Sbjct: 132 SLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNP--DPEISWF 189
Query: 298 RKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK- 355
+ +DP + K L S L I ++ + G ++CV N G+ L V+ +
Sbjct: 190 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRR 249
Query: 356 --PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKN 413
P P+ + G V L C P P W +L TK ++
Sbjct: 250 VAPRFSIPPSSQEVMPG-GSVN-LTCVAVGAPMPYVKWMMGAEEL-----TK------ED 296
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ +VL ++NV S +Y C A + LG T ++ V + P + L VT T ++
Sbjct: 297 EMPVGRNVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATS 354
Query: 474 VTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAI 533
VTL W G + ++Y I+YR + +++V T +++ GL ++Y F V+A+
Sbjct: 355 VTLTWDSG-NSEPVTYYGIQYRAAGTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAV 412
Query: 534 NKIGQ 538
N IG+
Sbjct: 413 NSIGR 417
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/150 (28%), Positives = 64/150 (42%), Gaps = 10/150 (6%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
S P+ T +G V C +TG P +TW K KK+ S + S
Sbjct: 51 SKPVFIKVPEDQTGLSGGVASFVCQATG-EPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 109
Query: 82 ILT----NVTDNQAQYRCEATNSATEIPLFETVTL--NVHFAPEAVKVRAEPD--VLKPG 133
+L V ++A Y C ATNS EI +++ P + P V++
Sbjct: 110 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 169
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQNA 163
AT++C +A NP +SW++D +PV A
Sbjct: 170 RTATMLC-AAGGNPDPEISWFKDFLPVDPA 198
Score = 44.0 bits (99), Expect = 0.002
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFD-G 484
+V + Y + GAR++ TTT V P ++S T N T L+W P +
Sbjct: 805 SVTVAAYTTKGDGARSKPKIVTTTGA--VPGRPTMMISTTAMN----TALLQWHPPKELP 858
Query: 485 GLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG-----QS 539
G YR++Y + D++ K +FTV GL K T YIF + A N+ G +
Sbjct: 859 GELLGYRLQYCRA-DEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEK 917
Query: 540 KYR-PDDTKATTLTSSEVGELSTVSTEYVETPDI 572
+ R P+D + + V L+T +TE P +
Sbjct: 918 EIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 951
Score = 41.1 bits (92), Expect = 0.016
Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 11/101 (10%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D+ P F+K + G V +C+ P P TW K G K+ S++ F +D
Sbjct: 50 DSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV----SSQRFEVIEFDD 105
Query: 415 HITYTSVLLINNVATS-DYGSYECGARNELGFSTTTVKLDV 454
SVL I + D YEC A N LG T+ KL V
Sbjct: 106 GA--GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV 144
Score = 37.1 bits (82), Expect = 0.26
Identities = 30/132 (22%), Positives = 49/132 (37%), Gaps = 4/132 (3%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKT--TDKAVS 77
PP P I + + C + GGNP ++WFK+ + T + S
Sbjct: 151 PPGFPSIDMGPQLKVVEKARTATMLC-AAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 209
Query: 78 AEISILTNVTDNQAQYRCEATNSA-TEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEA 136
+ I ++ +Q +Y C ATNSA T + + V + + PG
Sbjct: 210 GALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSV 269
Query: 137 TLICDSASSNPP 148
L C + + P
Sbjct: 270 NLTCVAVGAPMP 281
>AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin
superfamily, member 9 protein.
Length = 1163
Score = 97.9 bits (233), Expect = 1e-19
Identities = 101/415 (24%), Positives = 166/415 (40%), Gaps = 40/415 (9%)
Query: 133 GIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP 192
G C ++S+ AT + + V P+ +TV + + ++ A+ P
Sbjct: 199 GSSGVYTCQASSTEGSATHA---TQLLVLGPPVIVVPPKNSTVNASQD-VSLACHAEAYP 254
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
++TY+W +D + + S RI+ +GS L + DAG YTC V S G
Sbjct: 255 ANLTYSWFQDNINVFHISRLQPRVRILVDGS-LRLLATQPDDAGCYTC--VPSNGL---- 307
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEP 312
+H P+ S V+ P V+ C NP L + W + G +
Sbjct: 308 ----LHPPSA--SAYLTVLCMPG---VIRCPVRANPPLL-FVSWTKDGKALQLDKFPGWS 357
Query: 313 KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM-LIVKFKPEMDTSPNFVKSASNV 371
+ LII + LG + C N +G+A V +++K P P + V
Sbjct: 358 QGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPK-EEYFQEV 416
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G+ + C + P P +W+K G L A+ N S L++ +
Sbjct: 417 GRELLIPCSAQGDPPPVVSWTKVGRGLQGQ------AQVDSN------SSLILRPLTKEA 464
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYR 491
+G +EC A N + T+ + V VV+ + W PGFDGG +
Sbjct: 465 HGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGGYLQRFS 524
Query: 492 IRYRKVF--DDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ Y + D ++ V +P A + V GL+ +T Y FSV+A NK+G +
Sbjct: 525 VWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPF 579
Score = 49.6 bits (113), Expect = 5e-05
Identities = 48/209 (22%), Positives = 88/209 (42%), Gaps = 13/209 (6%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V + P F +T E EP+ + A G+P P +T W G + Q G
Sbjct: 130 LTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVT--WKLRGKDLGQ-----GQG 182
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
++ + L + ++ R +G+YTC+A +++G+A + V P I +N N ++
Sbjct: 183 QVQVQNGTLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQ 242
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPK---NLTSYLIIRKAKSENLGNFQ 333
D L+C A P + W + + S +P+ + L + + ++ G +
Sbjct: 243 DVSLACHAEAYPANLTY-SWFQDNINVFHIS-RLQPRVRILVDGSLRLLATQPDDAGCYT 300
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSP 362
CV +NG+ L V P + P
Sbjct: 301 CVPSNGLLHPPSASAYLTVLCMPGVIRCP 329
Score = 36.3 bits (80), Expect = 0.45
Identities = 44/169 (26%), Positives = 66/169 (39%), Gaps = 12/169 (7%)
Query: 6 DSGIFKCM-INSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKK 64
D+G + C+ N PPSA + Y+ T L V + C PL ++W K+ K
Sbjct: 295 DAGCYTCVPSNGLLHPPSA---SAYL--TVLCMPGV--IRCPVRANPPLLFVSWTKDGKA 347
Query: 65 IH-STTKTTDKAVSAEISILTNVTDNQAQYRCEATNS-ATEIPLFETVTLNVHFAPEAVK 122
+ + + I D +Y C NS T P VT + AP A
Sbjct: 348 LQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGP--SPVTRVLLKAPPAFI 405
Query: 123 VRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTS 171
R + + + LI SA +PP +SW + G +Q D +S
Sbjct: 406 ERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSS 454
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 96.7 bits (230), Expect = 3e-19
Identities = 87/306 (28%), Positives = 129/306 (42%), Gaps = 23/306 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTK-DGLPI-TQSSYSSGN 215
+ V +AP + TV + L+ + RA G PP T TW + DG P+ + G+
Sbjct: 43 LAVGHAPQLTELPRDVTVELGRSALL-ACRATGRPPP-TVTWRRGDGQPLGLRLGAGRGS 100
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGA--AVANISVSVHYPAGIKSVSQNVVAN 273
+ +L + D Y CEA N G A A + V+ H P I S + V
Sbjct: 101 RSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVL 160
Query: 274 PNEDAVLSCTAI-GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNF 332
+ L C + G PL H W + G + P S L + +A E+ G +
Sbjct: 161 EGQPVSLPCIVLAGRPLPERH--WLKDGRPLPPGSR--HSIRADGSLHLDRALQEHAGRY 216
Query: 333 QCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWS 392
CV N GS + DV L+V+ P + P +N G L C VPAP+ TW+
Sbjct: 217 SCVATNTAGSQHR-DVELVVQVPPRIH--PTATHHITNEGVPASLPCVASGVPAPTITWT 273
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K N T ++ ++ LLI + D G+Y C A N +GFS+ ++L
Sbjct: 274 KE-----TNALTSRGPHYN----VSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRL 324
Query: 453 DVTSAP 458
V + P
Sbjct: 325 SVNTKP 330
Score = 82.2 bits (194), Expect = 7e-15
Identities = 72/283 (25%), Positives = 124/283 (43%), Gaps = 23/283 (8%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+E +P+ + P W KDG P+ S S I ++GS L++ + + AG
Sbjct: 160 LEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHS----IRADGS-LHLDRALQEHAG 214
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
Y+C A N+ G+ ++ + V P I + + + N A L C A G P A I W
Sbjct: 215 RYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVP--APTITW 272
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
++ + + + L+I + +++ G + C N +G ++ Q++ L V KP
Sbjct: 273 TKETNALTSRGPHYNVSK-EGTLLIAQPSAQDAGAYVCTATNTVGFSS-QEMRLSVNTKP 330
Query: 357 E--MDTSPNF---VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
M+ S N ++ + G+ L C+ K P P TW+K+ +P T+ +Y
Sbjct: 331 RIHMNGSRNADVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITN-RY----- 384
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ + L + V D G YEC A N G ++ L V
Sbjct: 385 ---GLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGV 424
Score = 55.6 bits (128), Expect = 7e-07
Identities = 61/265 (23%), Positives = 94/265 (35%), Gaps = 28/265 (10%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
S L + DAG YTC AVN G A A I ++V + + + ++V A+
Sbjct: 8 SSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSAL 67
Query: 280 LSCTAIGNPLLAEHIKWER-----KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
L+C A G P + W R G ++ + + + L E+ + C
Sbjct: 68 LACRATGRP--PPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVC 125
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMC-KCKSVPAPSF 389
N G + +++ P P SA V GQ L C P P
Sbjct: 126 EARNVFGKVQAEARLIVTGHAP-----PQIASSAPTVRVLEGQPVSLPCIVLAGRPLPER 180
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
W K+G LP + A+ L ++ G Y C A N G
Sbjct: 181 HWLKDGRPLPPGSRHSIRAD----------GSLHLDRALQEHAGRYSCVATNTAGSQHRD 230
Query: 450 VKLDVTSAPDQVVSLTVTNVTHSTV 474
V+L V P ++ ++T+ V
Sbjct: 231 VEL-VVQVPPRIHPTATHHITNEGV 254
Score = 54.4 bits (125), Expect = 2e-06
Identities = 84/381 (22%), Positives = 150/381 (39%), Gaps = 60/381 (15%)
Query: 23 APMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKND-----KKIHSTTKTTDKAVS 77
AP +T T+ G LAC +T G P T+TW + D ++ + + +
Sbjct: 48 APQLTELPRDVTVELGRSALLACRAT-GRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPD 106
Query: 78 AEISILTNVT-DNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEA 136
+ + +V ++QA Y CEA N ++ + + H P+ VL+ G
Sbjct: 107 SGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLE-GQPV 165
Query: 137 TLICDSASSNPPATLSWWRDGIPVQ---------------NAPIFDDTTSY-----NTVG 176
+L C + P W +DG P+ + + + Y NT G
Sbjct: 166 SLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG 225
Query: 177 IENEPLIISVRADGN-PPSITYTWTKDGLPITQSSYSSG-----------NDRIISEGSM 224
++ + + V+ P+ T+ T +G+P + +SG + + S G
Sbjct: 226 SQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPH 285
Query: 225 LNMTK--------LTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGI-------KSVSQN 269
N++K + DAG Y C A N+ G + + +SV+ I V
Sbjct: 286 YNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQ 345
Query: 270 VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSEN 328
V A E+ L C A G+P + W + + P +T L S L + + + +
Sbjct: 346 VTAKAGEEVTLDCEAKGSP--PPLVTWTKDSRPVPP--ITNRYGLLPSGSLRLAQVQVGD 401
Query: 329 LGNFQCVVNNGIGSATKQDVM 349
G+++C +N GSA+ + V+
Sbjct: 402 SGHYECTASNPAGSASHRYVL 422
>BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin
superfamily, member 9 protein.
Length = 1163
Score = 96.3 bits (229), Expect = 4e-19
Identities = 100/415 (24%), Positives = 166/415 (40%), Gaps = 40/415 (9%)
Query: 133 GIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP 192
G C ++S+ AT + + V P+ +TV + + ++ A+ P
Sbjct: 199 GSSGVYTCQASSTEGSATHA---TQLLVLGPPVIVVPPKNSTVNASQD-VSLACHAEAYP 254
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
++TY+W +D + + S +I+ +GS L + DAG YTC V S G
Sbjct: 255 ANLTYSWFQDNINVFHISRLQPRVQILVDGS-LRLLATQPDDAGCYTC--VPSNGL---- 307
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEP 312
+H P+ S V+ P V+ C NP L + W + G +
Sbjct: 308 ----LHPPSA--SAYLTVLCMPG---VIRCPVRANPPLL-FVSWTKDGKALQLDKFPGWS 357
Query: 313 KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM-LIVKFKPEMDTSPNFVKSASNV 371
+ LII + LG + C N +G+A V +++K P P + V
Sbjct: 358 QGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPK-EEYFQEV 416
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G+ + C + P P +W+K G L A+ N S L++ +
Sbjct: 417 GRELLIPCSAQGDPPPVVSWTKVGRGLQGQ------AQVDSN------SSLILRPLTKEA 464
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYR 491
+G +EC A N + T+ + V VV+ + W PGFDGG +
Sbjct: 465 HGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGGYLQRFS 524
Query: 492 IRYRKVF--DDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ Y + D ++ V +P A + V GL+ +T Y FSV+A NK+G +
Sbjct: 525 VWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPF 579
Score = 49.6 bits (113), Expect = 5e-05
Identities = 48/209 (22%), Positives = 88/209 (42%), Gaps = 13/209 (6%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V + P F +T E EP+ + A G+P P +T W G + Q G
Sbjct: 130 LTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVT--WKLRGKDLGQ-----GQG 182
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
++ + L + ++ R +G+YTC+A +++G+A + V P I +N N ++
Sbjct: 183 QVQVQNGTLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQ 242
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPK---NLTSYLIIRKAKSENLGNFQ 333
D L+C A P + W + + S +P+ + L + + ++ G +
Sbjct: 243 DVSLACHAEAYPANLTY-SWFQDNINVFHIS-RLQPRVQILVDGSLRLLATQPDDAGCYT 300
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSP 362
CV +NG+ L V P + P
Sbjct: 301 CVPSNGLLHPPSASAYLTVLCMPGVIRCP 329
Score = 36.3 bits (80), Expect = 0.45
Identities = 44/169 (26%), Positives = 66/169 (39%), Gaps = 12/169 (7%)
Query: 6 DSGIFKCM-INSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKK 64
D+G + C+ N PPSA + Y+ T L V + C PL ++W K+ K
Sbjct: 295 DAGCYTCVPSNGLLHPPSA---SAYL--TVLCMPGV--IRCPVRANPPLLFVSWTKDGKA 347
Query: 65 IH-STTKTTDKAVSAEISILTNVTDNQAQYRCEATNS-ATEIPLFETVTLNVHFAPEAVK 122
+ + + I D +Y C NS T P VT + AP A
Sbjct: 348 LQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGP--SPVTRVLLKAPPAFI 405
Query: 123 VRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTS 171
R + + + LI SA +PP +SW + G +Q D +S
Sbjct: 406 ERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSS 454
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 94.7 bits (225), Expect = 1e-18
Identities = 99/405 (24%), Positives = 165/405 (40%), Gaps = 39/405 (9%)
Query: 154 WRDGIPVQNAP--IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSS 210
+RD I + N P I S+N E + S RA G+P P+I+ W ++G I +
Sbjct: 198 FRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAIS--WFRNGKLIEE-- 253
Query: 211 YSSGNDRIISEGSMLNMT--KLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ 268
N++ I +GS +T + D G Y C A N G + V I + +
Sbjct: 254 ----NEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQL-K 308
Query: 269 NVVANPNEDAVLSCTAIGNPLLAEHIKWER--------KGYKIDPKSVTFEPKNLTSYLI 320
N N L C A G P+ I W+R +G K + + ++ +S L
Sbjct: 309 NETTYENGQVTLVCDAEGEPI--PEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLH 366
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCK 380
I+ K G + C + IG K + L +++ P+ ++ S G + C
Sbjct: 367 IKDVKLSGSGRYDCEAASRIGGHQKS-MYLDIEYAPKFISNQTIYYSWE--GNPINISCD 423
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
KS P S W ++ + LP +T K +L I + +D+G Y C A
Sbjct: 424 VKSNPPASIHWRRDKLVLPAKNTTNL-----KTYSTGRKMILEIAPTSDNDFGRYNCTAT 478
Query: 441 NELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVF 498
N +G L + P + + ++ +T + + P GG+ Y++ ++V
Sbjct: 479 NHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVA 538
Query: 499 DDSYKYEDVLPKHA--TNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ +K ++ H T ++ LE NT Y V A+N GQ Y
Sbjct: 539 SEIWK---IVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQGDY 580
Score = 71.3 bits (167), Expect = 1e-11
Identities = 71/260 (27%), Positives = 111/260 (42%), Gaps = 15/260 (5%)
Query: 213 SGNDRIISEGSMLNMTKLTRHDAGIYTCEA-VNSQGAA-VANISVSVHYPAGIK--SVSQ 268
S N + + L + + + D GIY CE V ++G +I V V+ P I S
Sbjct: 159 SDNRLAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSF 218
Query: 269 NVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
N A E+ SC A G+P A I W R G K+ ++ + K + L +R + +
Sbjct: 219 NATAERGEEMTFSCRASGSPEPA--ISWFRNG-KLIEENEKYILKGSNTELTVRNIINSD 275
Query: 329 LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
G + C N G KQ L V +P + N ++ GQV L+C + P P
Sbjct: 276 GGPYVCRATNKAGEDEKQ-AFLQVFVQPHIIQLKN--ETTYENGQV-TLVCDAEGEPIPE 331
Query: 389 FTWSK--NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFS 446
TW + +G + K H +S L I +V S G Y+C A + +G
Sbjct: 332 ITWKRAVDGFTFTEGDKSPDGRIEVKGQH--GSSSLHIKDVKLSGSGRYDCEAASRIGGH 389
Query: 447 TTTVKLDVTSAPDQVVSLTV 466
++ LD+ AP + + T+
Sbjct: 390 QKSMYLDIEYAPKFISNQTI 409
Score = 63.3 bits (147), Expect = 3e-09
Identities = 57/256 (22%), Positives = 97/256 (37%), Gaps = 13/256 (5%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAV-ANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
S L + DAGIY C+A +++G A + + ++ + V EDA +
Sbjct: 76 SRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVV 135
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN-NGI 340
C +P A + W ++ S + L I + G ++C
Sbjct: 136 CRVSSSP--APAVSWLYHNEEVTTISDNRLAMLANNNLQILNINKSDEGIYRCEGRVEAR 193
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV 400
G +D+++IV P + + + G+ C+ P P+ +W +NG KL +
Sbjct: 194 GEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNG-KL-I 251
Query: 401 NTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQ 460
+ KY + + L + N+ SD G Y C A N+ G L V P
Sbjct: 252 EENEKYILKGSNTE-------LTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHI 304
Query: 461 VVSLTVTNVTHSTVTL 476
+ T + VTL
Sbjct: 305 IQLKNETTYENGQVTL 320
Score = 49.2 bits (112), Expect = 6e-05
Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T G +C ++G +P ++WF+N K I K K + E+++ + + Y
Sbjct: 221 TAERGEEMTFSCRASG-SPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPY 279
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSW 153
C ATN A E + L V P ++++ E + G + TL+CD A P ++W
Sbjct: 280 VCRATNKAGEDE--KQAFLQVFVQPHIIQLKNE-TTYENG-QVTLVCD-AEGEPIPEITW 334
Query: 154 WR 155
R
Sbjct: 335 KR 336
Score = 34.7 bits (76), Expect = 1.4
Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 8/122 (6%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFK-NDKKIHSTTKTTDK--AVSAEISILTNVTDNQA 91
L+ G + C + G P ++ W+ +KI ST + + V + ++I ++
Sbjct: 32 LSVGESKFFTCTAIG-EP-RSIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAG 89
Query: 92 QYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATL 151
YRC+AT++ + TV L ++ +V P K G +A ++C SS+P +
Sbjct: 90 IYRCQATDAKGQTQE-ATVVLEIYQKLTFREV-VSPQEFKQGEDAEVVC-RVSSSPAPAV 146
Query: 152 SW 153
SW
Sbjct: 147 SW 148
Score = 33.1 bits (72), Expect = 4.2
Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 12/146 (8%)
Query: 51 NPLATLTWFKNDKKIHSTTKTTDKAVSAE--ISILTNVTDNQAQYRCEATNSATEIPLFE 108
+P ++W +++++ +T A+ A + IL ++ YRCE A F
Sbjct: 141 SPAPAVSWLYHNEEV-TTISDNRLAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFR 199
Query: 109 TVTLNVHFAPE-AVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFD 167
+ + V+ P ++ ++ + G E T C AS +P +SW+R+G + +
Sbjct: 200 DIIVIVNVPPAISMPQKSFNATAERGEEMTFSC-RASGSPEPAISWFRNG------KLIE 252
Query: 168 DTTSYNTVGIENEPLIIS-VRADGNP 192
+ Y G E + + + +DG P
Sbjct: 253 ENEKYILKGSNTELTVRNIINSDGGP 278
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 812
Score = 94.3 bits (224), Expect = 2e-18
Identities = 84/289 (29%), Positives = 123/289 (42%), Gaps = 22/289 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG---SMLNMTKLTRHDAG 236
EP+ + G P T TWT D PI + + I SEG S LN++ D G
Sbjct: 252 EPVSLMCNVKGTPLP-TITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG 310
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A NS G + ++V PA I+ + +N+ A D + C IG P + IKW
Sbjct: 311 VYRCTANNSAGVVLYQARINVRGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYS--IKW 367
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ + + V FE ++K E G + C V +T Q V + VK
Sbjct: 368 YKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDE--GEYTCNVLVQPQLSTSQSVHVTVKV 425
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP-SFTWSKNGVKLPVNTSTKYFAEFHKN 413
P + F ++GQ + C S P + TW K+G +P +
Sbjct: 426 PPFIQP---FEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTI------- 475
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
D+I +TS L I+N++ G+Y C ARNE +L V P VV
Sbjct: 476 DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVV 524
Score = 89.4 bits (212), Expect = 5e-17
Identities = 96/386 (24%), Positives = 158/386 (40%), Gaps = 20/386 (5%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
P F + I I V G+ P IT TW KDG PI S + ++ I S
Sbjct: 426 PPFIQPFEFPRFSIGQRVFIPCVVVSGDLP-ITITWQKDGRPIPGSLGVTIDN--IDFTS 482
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L ++ L+ G YTC A N A + V P ++ + +L+C+
Sbjct: 483 SLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCS 542
Query: 284 AIGNPLLAEHIKWE-RKGYKI---DPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNN 338
A G P+ I W+ KG + P ++ + L++ L+I+ E+ G + C V+N
Sbjct: 543 AEGYPVPT--IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSN 600
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+G+ + + L VK + + PN + + GQ + C W K
Sbjct: 601 DVGADVSKSMYLTVKIPAMITSYPN--TTLATQGQKKEMSCTAHGEKPIIVRWEKE--DR 656
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+N + K S L I D G + C A N G ++L V P
Sbjct: 657 IINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 716
Query: 459 DQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRK---VFDDSYKYEDVLPKHATN 514
D + + +V T+TL W GFDG + Y I + +D + + +DV P+ +
Sbjct: 717 DP-PEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQ-LNS 774
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
T+ + ++ Y + A N+IG+S+
Sbjct: 775 ATIIDIHPSSTYSIRMYAKNRIGKSE 800
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/297 (23%), Positives = 115/297 (38%), Gaps = 16/297 (5%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P +AP D + + + + + +A G+P Y W KD +P+ S R
Sbjct: 50 PANSAPSILDGFDHRKA-MAGQRVELPCKALGHPEP-DYRWLKDNMPLELSG------RF 101
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
+ L + + D+G Y CE N G A + V P + V ++
Sbjct: 102 QKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQV 161
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
LSC+ G + + W R G ++P K+V N + ++ KS+ G +QC V
Sbjct: 162 SLSCSVTGTE--DQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDG-GAYQCFVR 218
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
SA QD + +V F + + + LMC K P P+ TW+ +
Sbjct: 219 KDKLSA--QDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDP 276
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ S + ++ S L I++ D G Y C A N G +++V
Sbjct: 277 ILKGGSHRISQMITSEGNV--VSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV 331
Score = 49.2 bits (112), Expect = 6e-05
Identities = 49/183 (26%), Positives = 77/183 (42%), Gaps = 18/183 (9%)
Query: 316 TSYLIIRKAKSEN-LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASN---- 370
T L I+ ++E+ L N++C+ + T+Q + +++P+ + +
Sbjct: 8 TGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAM 67
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
GQ L CK P P + W K+ + L ++ F K T T LLI N+ S
Sbjct: 68 AGQRVELPCKALGHPEPDYRWLKDNMPLELS------GRFQK----TVTG-LLIENIRPS 116
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQS 488
D GSY C N G + +L V +S V + S V+L V G + S
Sbjct: 117 DSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS 176
Query: 489 WYR 491
WYR
Sbjct: 177 WYR 179
Score = 39.1 bits (87), Expect = 0.064
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 25 MITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHS-------TTKTTDKAV 76
MIT Y P TTLA G ++++C + G P+ + W K D+ I+ +TK + V
Sbjct: 619 MITSY-PNTTLATQGQKKEMSCTAHGEKPII-VRWEKEDRIINPEMARYLVSTKEVGEEV 676
Query: 77 SAEISILTNVTDNQAQYRCEATNSATE 103
+ + IL V ++ + C A NS E
Sbjct: 677 ISTLQILPTVREDSGFFSCHAINSYGE 703
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell
adhesion molecule splice variant protein.
Length = 1746
Score = 94.3 bits (224), Expect = 2e-18
Identities = 84/289 (29%), Positives = 123/289 (42%), Gaps = 22/289 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG---SMLNMTKLTRHDAG 236
EP+ + G P T TWT D PI + + I SEG S LN++ D G
Sbjct: 174 EPVSLMCNVKGTPLP-TITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG 232
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A NS G + ++V PA I+ + +N+ A D + C IG P + IKW
Sbjct: 233 VYRCTANNSAGVVLYQARINVRGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYS--IKW 289
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ + + V FE ++K E G + C V +T Q V + VK
Sbjct: 290 YKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDE--GEYTCNVLVQPQLSTSQSVHVTVKV 347
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP-SFTWSKNGVKLPVNTSTKYFAEFHKN 413
P + F ++GQ + C S P + TW K+G +P +
Sbjct: 348 PPFIQP---FEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTI------- 397
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
D+I +TS L I+N++ G+Y C ARNE +L V P VV
Sbjct: 398 DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVV 446
Score = 89.4 bits (212), Expect = 5e-17
Identities = 96/386 (24%), Positives = 158/386 (40%), Gaps = 20/386 (5%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
P F + I I V G+ P IT TW KDG PI S + ++ I S
Sbjct: 348 PPFIQPFEFPRFSIGQRVFIPCVVVSGDLP-ITITWQKDGRPIPGSLGVTIDN--IDFTS 404
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L ++ L+ G YTC A N A + V P ++ + +L+C+
Sbjct: 405 SLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCS 464
Query: 284 AIGNPLLAEHIKWE-RKGYKI---DPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNN 338
A G P+ I W+ KG + P ++ + L++ L+I+ E+ G + C V+N
Sbjct: 465 AEGYPVPT--IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSN 522
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+G+ + + L VK + + PN + + GQ + C W K
Sbjct: 523 DVGADVSKSMYLTVKIPAMITSYPN--TTLATQGQKKEMSCTAHGEKPIIVRWEKE--DR 578
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+N + K S L I D G + C A N G ++L V P
Sbjct: 579 IINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 638
Query: 459 DQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRK---VFDDSYKYEDVLPKHATN 514
D + + +V T+TL W GFDG + Y I + +D + + +DV P+ +
Sbjct: 639 DP-PEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQ-LNS 696
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
T+ + ++ Y + A N+IG+S+
Sbjct: 697 ATIIDIHPSSTYSIRMYAKNRIGKSE 722
Score = 67.3 bits (157), Expect = 2e-10
Identities = 63/263 (23%), Positives = 101/263 (38%), Gaps = 14/263 (5%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P Y W KD +P+ S R + L + + D+G Y CE N G A
Sbjct: 4 PEPDYRWLKDNMPLELSG------RFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI 57
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFE 311
+ V P + V ++ LSC+ G + + W R G ++P K+V
Sbjct: 58 GRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTE--DQELSWYRNGEILNPGKNVRIT 115
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV 371
N + ++ KS+ G +QC V SA QD + +V F + +
Sbjct: 116 GINHENLIMDHMVKSDG-GAYQCFVRKDKLSA--QDYVQVVLEDGTPKIISAFSEKVVSP 172
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
+ LMC K P P+ TW+ + + S + ++ S L I++ D
Sbjct: 173 AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNV--VSYLNISSSQVRD 230
Query: 432 YGSYECGARNELGFSTTTVKLDV 454
G Y C A N G +++V
Sbjct: 231 GGVYRCTANNSAGVVLYQARINV 253
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L CK P+P+ W K+ + T I +I V D G Y
Sbjct: 1057 LPCKAVGDPSPAVKWMKD------SNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1110
Query: 437 CGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYR 495
C A N G + L V PDQ LTV+ T S++TL W+PG +GG Y ++Y
Sbjct: 1111 CIANNNWGSDEIILNLQVQVPPDQP-RLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1169
Query: 496 KVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + + + P ++ + L+ T Y F++ A N +G +
Sbjct: 1170 EDNSEQWGSFPISPSE-RSYRLENLKCGTWYKFTLTAQNGVGPGR 1213
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
Query: 260 PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL---T 316
PA I + S V +D VL C A+G+P A +KW K P VT + +
Sbjct: 1037 PARILTFSGTVTTPWMKDIVLPCKAVGDPSPA--VKW-MKDSNGTPSLVTIDGRRSIFSN 1093
Query: 317 SYLIIRKAKSENLGNFQCVVNNGIGS 342
IIR K+E+ G + C+ NN GS
Sbjct: 1094 GSFIIRTVKAEDSGYYSCIANNNWGS 1119
Score = 39.1 bits (87), Expect = 0.064
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 25 MITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHS-------TTKTTDKAV 76
MIT Y P TTLA G ++++C + G P+ + W K D+ I+ +TK + V
Sbjct: 541 MITSY-PNTTLATQGQKKEMSCTAHGEKPII-VRWEKEDRIINPEMARYLVSTKEVGEEV 598
Query: 77 SAEISILTNVTDNQAQYRCEATNSATE 103
+ + IL V ++ + C A NS E
Sbjct: 599 ISTLQILPTVREDSGFFSCHAINSYGE 625
Score = 35.9 bits (79), Expect = 0.60
Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 13/109 (11%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P + W K+ + L ++ F K T T LLI N+ SD GSY C N G
Sbjct: 4 PEPDYRWLKDNMPLELS------GRFQK----TVTG-LLIENIRPSDSGSYVCEVSNRYG 52
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSWYR 491
+ +L V +S V + S V+L V G + SWYR
Sbjct: 53 TAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYR 101
Score = 33.9 bits (74), Expect = 2.4
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P+ AP T S + +++ +A G+P S W KD G I
Sbjct: 1032 PLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDP-SPAVKWMKDSNGTPSLVTIDGRRSI 1090
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYP 260
S GS + T + D+G Y+C A N+ G+ +++ V P
Sbjct: 1091 FSNGSFIIRT-VKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1131
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 2012
Score = 94.3 bits (224), Expect = 2e-18
Identities = 84/289 (29%), Positives = 123/289 (42%), Gaps = 22/289 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG---SMLNMTKLTRHDAG 236
EP+ + G P T TWT D PI + + I SEG S LN++ D G
Sbjct: 422 EPVSLMCNVKGTPLP-TITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG 480
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A NS G + ++V PA I+ + +N+ A D + C IG P + IKW
Sbjct: 481 VYRCTANNSAGVVLYQARINVRGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYS--IKW 537
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ + + V FE ++K E G + C V +T Q V + VK
Sbjct: 538 YKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDE--GEYTCNVLVQPQLSTSQSVHVTVKV 595
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP-SFTWSKNGVKLPVNTSTKYFAEFHKN 413
P + F ++GQ + C S P + TW K+G +P +
Sbjct: 596 PPFIQP---FEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTI------- 645
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
D+I +TS L I+N++ G+Y C ARNE +L V P VV
Sbjct: 646 DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVV 694
Score = 89.4 bits (212), Expect = 5e-17
Identities = 96/386 (24%), Positives = 158/386 (40%), Gaps = 20/386 (5%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
P F + I I V G+ P IT TW KDG PI S + ++ I S
Sbjct: 596 PPFIQPFEFPRFSIGQRVFIPCVVVSGDLP-ITITWQKDGRPIPGSLGVTIDN--IDFTS 652
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L ++ L+ G YTC A N A + V P ++ + +L+C+
Sbjct: 653 SLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCS 712
Query: 284 AIGNPLLAEHIKWE-RKGYKI---DPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNN 338
A G P+ I W+ KG + P ++ + L++ L+I+ E+ G + C V+N
Sbjct: 713 AEGYPVPT--IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSN 770
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+G+ + + L VK + + PN + + GQ + C W K
Sbjct: 771 DVGADVSKSMYLTVKIPAMITSYPN--TTLATQGQKKEMSCTAHGEKPIIVRWEKE--DR 826
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+N + K S L I D G + C A N G ++L V P
Sbjct: 827 IINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 886
Query: 459 DQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRK---VFDDSYKYEDVLPKHATN 514
D + + +V T+TL W GFDG + Y I + +D + + +DV P+ +
Sbjct: 887 DP-PEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQ-LNS 944
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
T+ + ++ Y + A N+IG+S+
Sbjct: 945 ATIIDIHPSSTYSIRMYAKNRIGKSE 970
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/297 (23%), Positives = 115/297 (38%), Gaps = 16/297 (5%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P +AP D + + + + + +A G+P Y W KD +P+ S R
Sbjct: 220 PANSAPSILDGFDHRKA-MAGQRVELPCKALGHPEP-DYRWLKDNMPLELSG------RF 271
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
+ L + + D+G Y CE N G A + V P + V ++
Sbjct: 272 QKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQV 331
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
LSC+ G + + W R G ++P K+V N + ++ KS+ G +QC V
Sbjct: 332 SLSCSVTGTE--DQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDG-GAYQCFVR 388
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
SA QD + +V F + + + LMC K P P+ TW+ +
Sbjct: 389 KDKLSA--QDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDP 446
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ S + ++ S L I++ D G Y C A N G +++V
Sbjct: 447 ILKGGSHRISQMITSEGNV--VSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV 501
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L CK P+P+ W K+ + T I +I V D G Y
Sbjct: 1305 LPCKAVGDPSPAVKWMKD------SNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1358
Query: 437 CGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYR 495
C A N G + L V PDQ LTV+ T S++TL W+PG +GG Y ++Y
Sbjct: 1359 CIANNNWGSDEIILNLQVQVPPDQP-RLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1417
Query: 496 KVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + + + P ++ + L+ T Y F++ A N +G +
Sbjct: 1418 EDNSEQWGSFPISPSE-RSYRLENLKCGTWYKFTLTAQNGVGPGR 1461
Score = 49.2 bits (112), Expect = 6e-05
Identities = 49/183 (26%), Positives = 77/183 (42%), Gaps = 18/183 (9%)
Query: 316 TSYLIIRKAKSEN-LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASN---- 370
T L I+ ++E+ L N++C+ + T+Q + +++P+ + +
Sbjct: 178 TGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAM 237
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
GQ L CK P P + W K+ + L ++ F K T T LLI N+ S
Sbjct: 238 AGQRVELPCKALGHPEPDYRWLKDNMPLELS------GRFQK----TVTG-LLIENIRPS 286
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQS 488
D GSY C N G + +L V +S V + S V+L V G + S
Sbjct: 287 DSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS 346
Query: 489 WYR 491
WYR
Sbjct: 347 WYR 349
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
Query: 260 PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL---T 316
PA I + S V +D VL C A+G+P A +KW K P VT + +
Sbjct: 1285 PARILTFSGTVTTPWMKDIVLPCKAVGDPSPA--VKW-MKDSNGTPSLVTIDGRRSIFSN 1341
Query: 317 SYLIIRKAKSENLGNFQCVVNNGIGS 342
IIR K+E+ G + C+ NN GS
Sbjct: 1342 GSFIIRTVKAEDSGYYSCIANNNWGS 1367
Score = 39.1 bits (87), Expect = 0.064
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 25 MITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHS-------TTKTTDKAV 76
MIT Y P TTLA G ++++C + G P+ + W K D+ I+ +TK + V
Sbjct: 789 MITSY-PNTTLATQGQKKEMSCTAHGEKPII-VRWEKEDRIINPEMARYLVSTKEVGEEV 846
Query: 77 SAEISILTNVTDNQAQYRCEATNSATE 103
+ + IL V ++ + C A NS E
Sbjct: 847 ISTLQILPTVREDSGFFSCHAINSYGE 873
Score = 33.9 bits (74), Expect = 2.4
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P+ AP T S + +++ +A G+P S W KD G I
Sbjct: 1280 PLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDP-SPAVKWMKDSNGTPSLVTIDGRRSI 1338
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYP 260
S GS + T + D+G Y+C A N+ G+ +++ V P
Sbjct: 1339 FSNGSFIIRT-VKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1379
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1571
Score = 94.3 bits (224), Expect = 2e-18
Identities = 84/289 (29%), Positives = 123/289 (42%), Gaps = 22/289 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG---SMLNMTKLTRHDAG 236
EP+ + G P T TWT D PI + + I SEG S LN++ D G
Sbjct: 422 EPVSLMCNVKGTPLP-TITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG 480
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A NS G + ++V PA I+ + +N+ A D + C IG P + IKW
Sbjct: 481 VYRCTANNSAGVVLYQARINVRGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYS--IKW 537
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ + + V FE ++K E G + C V +T Q V + VK
Sbjct: 538 YKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDE--GEYTCNVLVQPQLSTSQSVHVTVKV 595
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP-SFTWSKNGVKLPVNTSTKYFAEFHKN 413
P + F ++GQ + C S P + TW K+G +P +
Sbjct: 596 PPFIQP---FEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTI------- 645
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
D+I +TS L I+N++ G+Y C ARNE +L V P VV
Sbjct: 646 DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVV 694
Score = 89.4 bits (212), Expect = 5e-17
Identities = 96/386 (24%), Positives = 158/386 (40%), Gaps = 20/386 (5%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
P F + I I V G+ P IT TW KDG PI S + ++ I S
Sbjct: 596 PPFIQPFEFPRFSIGQRVFIPCVVVSGDLP-ITITWQKDGRPIPGSLGVTIDN--IDFTS 652
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L ++ L+ G YTC A N A + V P ++ + +L+C+
Sbjct: 653 SLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCS 712
Query: 284 AIGNPLLAEHIKWE-RKGYKI---DPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNN 338
A G P+ I W+ KG + P ++ + L++ L+I+ E+ G + C V+N
Sbjct: 713 AEGYPVPT--IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSN 770
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+G+ + + L VK + + PN + + GQ + C W K
Sbjct: 771 DVGADVSKSMYLTVKIPAMITSYPN--TTLATQGQKKEMSCTAHGEKPIIVRWEKE--DR 826
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+N + K S L I D G + C A N G ++L V P
Sbjct: 827 IINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 886
Query: 459 DQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRK---VFDDSYKYEDVLPKHATN 514
D + + +V T+TL W GFDG + Y I + +D + + +DV P+ +
Sbjct: 887 DP-PEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQ-LNS 944
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
T+ + ++ Y + A N+IG+S+
Sbjct: 945 ATIIDIHPSSTYSIRMYAKNRIGKSE 970
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/297 (23%), Positives = 115/297 (38%), Gaps = 16/297 (5%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P +AP D + + + + + +A G+P Y W KD +P+ S R
Sbjct: 220 PANSAPSILDGFDHRKA-MAGQRVELPCKALGHPEP-DYRWLKDNMPLELSG------RF 271
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
+ L + + D+G Y CE N G A + V P + V ++
Sbjct: 272 QKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQV 331
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
LSC+ G + + W R G ++P K+V N + ++ KS+ G +QC V
Sbjct: 332 SLSCSVTGTE--DQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDG-GAYQCFVR 388
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
SA QD + +V F + + + LMC K P P+ TW+ +
Sbjct: 389 KDKLSA--QDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDP 446
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ S + ++ S L I++ D G Y C A N G +++V
Sbjct: 447 ILKGGSHRISQMITSEGNV--VSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV 501
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L CK P+P+ W K+ + T I +I V D G Y
Sbjct: 1305 LPCKAVGDPSPAVKWMKD------SNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1358
Query: 437 CGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYR 495
C A N G + L V PDQ LTV+ T S++TL W+PG +GG Y ++Y
Sbjct: 1359 CIANNNWGSDEIILNLQVQVPPDQP-RLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1417
Query: 496 KVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + + + P ++ + L+ T Y F++ A N +G +
Sbjct: 1418 EDNSEQWGSFPISPSE-RSYRLENLKCGTWYKFTLTAQNGVGPGR 1461
Score = 49.2 bits (112), Expect = 6e-05
Identities = 49/183 (26%), Positives = 77/183 (42%), Gaps = 18/183 (9%)
Query: 316 TSYLIIRKAKSEN-LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASN---- 370
T L I+ ++E+ L N++C+ + T+Q + +++P+ + +
Sbjct: 178 TGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAM 237
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
GQ L CK P P + W K+ + L ++ F K T T LLI N+ S
Sbjct: 238 AGQRVELPCKALGHPEPDYRWLKDNMPLELS------GRFQK----TVTG-LLIENIRPS 286
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQS 488
D GSY C N G + +L V +S V + S V+L V G + S
Sbjct: 287 DSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS 346
Query: 489 WYR 491
WYR
Sbjct: 347 WYR 349
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
Query: 260 PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL---T 316
PA I + S V +D VL C A+G+P A +KW K P VT + +
Sbjct: 1285 PARILTFSGTVTTPWMKDIVLPCKAVGDPSPA--VKW-MKDSNGTPSLVTIDGRRSIFSN 1341
Query: 317 SYLIIRKAKSENLGNFQCVVNNGIGS 342
IIR K+E+ G + C+ NN GS
Sbjct: 1342 GSFIIRTVKAEDSGYYSCIANNNWGS 1367
Score = 39.1 bits (87), Expect = 0.064
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 25 MITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHS-------TTKTTDKAV 76
MIT Y P TTLA G ++++C + G P+ + W K D+ I+ +TK + V
Sbjct: 789 MITSY-PNTTLATQGQKKEMSCTAHGEKPII-VRWEKEDRIINPEMARYLVSTKEVGEEV 846
Query: 77 SAEISILTNVTDNQAQYRCEATNSATE 103
+ + IL V ++ + C A NS E
Sbjct: 847 ISTLQILPTVREDSGFFSCHAINSYGE 873
Score = 33.9 bits (74), Expect = 2.4
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P+ AP T S + +++ +A G+P S W KD G I
Sbjct: 1280 PLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDP-SPAVKWMKDSNGTPSLVTIDGRRSI 1338
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYP 260
S GS + T + D+G Y+C A N+ G+ +++ V P
Sbjct: 1339 FSNGSFIIRT-VKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1379
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1896
Score = 94.3 bits (224), Expect = 2e-18
Identities = 84/289 (29%), Positives = 123/289 (42%), Gaps = 22/289 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG---SMLNMTKLTRHDAG 236
EP+ + G P T TWT D PI + + I SEG S LN++ D G
Sbjct: 408 EPVSLMCNVKGTPLP-TITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG 466
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A NS G + ++V PA I+ + +N+ A D + C IG P + IKW
Sbjct: 467 VYRCTANNSAGVVLYQARINVRGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYS--IKW 523
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ + + V FE ++K E G + C V +T Q V + VK
Sbjct: 524 YKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDE--GEYTCNVLVQPQLSTSQSVHVTVKV 581
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP-SFTWSKNGVKLPVNTSTKYFAEFHKN 413
P + F ++GQ + C S P + TW K+G +P +
Sbjct: 582 PPFIQP---FEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTI------- 631
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
D+I +TS L I+N++ G+Y C ARNE +L V P VV
Sbjct: 632 DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVV 680
Score = 89.4 bits (212), Expect = 5e-17
Identities = 96/386 (24%), Positives = 158/386 (40%), Gaps = 20/386 (5%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
P F + I I V G+ P IT TW KDG PI S + ++ I S
Sbjct: 582 PPFIQPFEFPRFSIGQRVFIPCVVVSGDLP-ITITWQKDGRPIPGSLGVTIDN--IDFTS 638
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L ++ L+ G YTC A N A + V P ++ + +L+C+
Sbjct: 639 SLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCS 698
Query: 284 AIGNPLLAEHIKWE-RKGYKI---DPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNN 338
A G P+ I W+ KG + P ++ + L++ L+I+ E+ G + C V+N
Sbjct: 699 AEGYPVPT--IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSN 756
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+G+ + + L VK + + PN + + GQ + C W K
Sbjct: 757 DVGADVSKSMYLTVKIPAMITSYPN--TTLATQGQKKEMSCTAHGEKPIIVRWEKE--DR 812
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+N + K S L I D G + C A N G ++L V P
Sbjct: 813 IINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 872
Query: 459 DQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRK---VFDDSYKYEDVLPKHATN 514
D + + +V T+TL W GFDG + Y I + +D + + +DV P+ +
Sbjct: 873 DP-PEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQ-LNS 930
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
T+ + ++ Y + A N+IG+S+
Sbjct: 931 ATIIDIHPSSTYSIRMYAKNRIGKSE 956
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/297 (23%), Positives = 115/297 (38%), Gaps = 16/297 (5%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P +AP D + + + + + +A G+P Y W KD +P+ S R
Sbjct: 206 PANSAPSILDGFDHRKA-MAGQRVELPCKALGHPEP-DYRWLKDNMPLELSG------RF 257
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
+ L + + D+G Y CE N G A + V P + V ++
Sbjct: 258 QKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQV 317
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
LSC+ G + + W R G ++P K+V N + ++ KS+ G +QC V
Sbjct: 318 SLSCSVTGTE--DQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDG-GAYQCFVR 374
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
SA QD + +V F + + + LMC K P P+ TW+ +
Sbjct: 375 KDKLSA--QDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDP 432
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ S + ++ S L I++ D G Y C A N G +++V
Sbjct: 433 ILKGGSHRISQMITSEGNV--VSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV 487
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L CK P+P+ W K+ + T I +I V D G Y
Sbjct: 1291 LPCKAVGDPSPAVKWMKD------SNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1344
Query: 437 CGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYR 495
C A N G + L V PDQ LTV+ T S++TL W+PG +GG Y ++Y
Sbjct: 1345 CIANNNWGSDEIILNLQVQVPPDQP-RLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1403
Query: 496 KVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + + + P ++ + L+ T Y F++ A N +G +
Sbjct: 1404 EDNSEQWGSFPISPSE-RSYRLENLKCGTWYKFTLTAQNGVGPGR 1447
Score = 49.2 bits (112), Expect = 6e-05
Identities = 49/183 (26%), Positives = 77/183 (42%), Gaps = 18/183 (9%)
Query: 316 TSYLIIRKAKSEN-LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASN---- 370
T L I+ ++E+ L N++C+ + T+Q + +++P+ + +
Sbjct: 164 TGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAM 223
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
GQ L CK P P + W K+ + L ++ F K T T LLI N+ S
Sbjct: 224 AGQRVELPCKALGHPEPDYRWLKDNMPLELS------GRFQK----TVTG-LLIENIRPS 272
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQS 488
D GSY C N G + +L V +S V + S V+L V G + S
Sbjct: 273 DSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS 332
Query: 489 WYR 491
WYR
Sbjct: 333 WYR 335
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
Query: 260 PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL---T 316
PA I + S V +D VL C A+G+P A +KW K P VT + +
Sbjct: 1271 PARILTFSGTVTTPWMKDIVLPCKAVGDPSPA--VKW-MKDSNGTPSLVTIDGRRSIFSN 1327
Query: 317 SYLIIRKAKSENLGNFQCVVNNGIGS 342
IIR K+E+ G + C+ NN GS
Sbjct: 1328 GSFIIRTVKAEDSGYYSCIANNNWGS 1353
Score = 39.1 bits (87), Expect = 0.064
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 25 MITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHS-------TTKTTDKAV 76
MIT Y P TTLA G ++++C + G P+ + W K D+ I+ +TK + V
Sbjct: 775 MITSY-PNTTLATQGQKKEMSCTAHGEKPII-VRWEKEDRIINPEMARYLVSTKEVGEEV 832
Query: 77 SAEISILTNVTDNQAQYRCEATNSATE 103
+ + IL V ++ + C A NS E
Sbjct: 833 ISTLQILPTVREDSGFFSCHAINSYGE 859
Score = 33.9 bits (74), Expect = 2.4
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P+ AP T S + +++ +A G+P S W KD G I
Sbjct: 1266 PLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDP-SPAVKWMKDSNGTPSLVTIDGRRSI 1324
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYP 260
S GS + T + D+G Y+C A N+ G+ +++ V P
Sbjct: 1325 FSNGSFIIRT-VKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1365
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell
adhesion molecule isoform CHD2-42 precursor variant
protein.
Length = 2023
Score = 94.3 bits (224), Expect = 2e-18
Identities = 84/289 (29%), Positives = 123/289 (42%), Gaps = 22/289 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG---SMLNMTKLTRHDAG 236
EP+ + G P T TWT D PI + + I SEG S LN++ D G
Sbjct: 433 EPVSLMCNVKGTPLP-TITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG 491
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+Y C A NS G + ++V PA I+ + +N+ A D + C IG P + IKW
Sbjct: 492 VYRCTANNSAGVVLYQARINVRGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYS--IKW 548
Query: 297 ERKG--YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
+ + + V FE ++K E G + C V +T Q V + VK
Sbjct: 549 YKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDE--GEYTCNVLVQPQLSTSQSVHVTVKV 606
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP-SFTWSKNGVKLPVNTSTKYFAEFHKN 413
P + F ++GQ + C S P + TW K+G +P +
Sbjct: 607 PPFIQP---FEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTI------- 656
Query: 414 DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
D+I +TS L I+N++ G+Y C ARNE +L V P VV
Sbjct: 657 DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVV 705
Score = 89.4 bits (212), Expect = 5e-17
Identities = 96/386 (24%), Positives = 158/386 (40%), Gaps = 20/386 (5%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
P F + I I V G+ P IT TW KDG PI S + ++ I S
Sbjct: 607 PPFIQPFEFPRFSIGQRVFIPCVVVSGDLP-ITITWQKDGRPIPGSLGVTIDN--IDFTS 663
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L ++ L+ G YTC A N A + V P ++ + +L+C+
Sbjct: 664 SLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCS 723
Query: 284 AIGNPLLAEHIKWE-RKGYKI---DPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNN 338
A G P+ I W+ KG + P ++ + L++ L+I+ E+ G + C V+N
Sbjct: 724 AEGYPVPT--IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSN 781
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+G+ + + L VK + + PN + + GQ + C W K
Sbjct: 782 DVGADVSKSMYLTVKIPAMITSYPN--TTLATQGQKKEMSCTAHGEKPIIVRWEKE--DR 837
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+N + K S L I D G + C A N G ++L V P
Sbjct: 838 IINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 897
Query: 459 DQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRK---VFDDSYKYEDVLPKHATN 514
D + + +V T+TL W GFDG + Y I + +D + + +DV P+ +
Sbjct: 898 DP-PEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQ-LNS 955
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
T+ + ++ Y + A N+IG+S+
Sbjct: 956 ATIIDIHPSSTYSIRMYAKNRIGKSE 981
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/297 (23%), Positives = 115/297 (38%), Gaps = 16/297 (5%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P +AP D + + + + + +A G+P Y W KD +P+ S R
Sbjct: 231 PANSAPSILDGFEHRKA-MAGQRVELPCKALGHPEP-DYRWLKDNMPLELSG------RF 282
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
+ L + + D+G Y CE N G A + V P + V ++
Sbjct: 283 QKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQV 342
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
LSC+ G + + W R G ++P K+V N + ++ KS+ G +QC V
Sbjct: 343 SLSCSVTGTE--DQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDG-GAYQCFVR 399
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
SA QD + +V F + + + LMC K P P+ TW+ +
Sbjct: 400 KDKLSA--QDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDP 457
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ S + ++ S L I++ D G Y C A N G +++V
Sbjct: 458 ILKGGSHRISQMITSEGNV--VSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV 512
Score = 63.7 bits (148), Expect = 3e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L CK P+P+ W K+ + T I +I V D G Y
Sbjct: 1316 LPCKAVGDPSPAVKWMKD------SNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1369
Query: 437 CGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYR 495
C A N G + L V PDQ LTV+ T S++TL W+PG +GG Y ++Y
Sbjct: 1370 CIANNNWGSDEIILNLQVQVPPDQP-RLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1428
Query: 496 KVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + + + P ++ + L+ T Y F++ A N +G +
Sbjct: 1429 EDNSEQWGSFPISPSE-RSYRLENLKCGTWYKFTLTAQNGVGPGR 1472
Score = 49.6 bits (113), Expect = 5e-05
Identities = 50/183 (27%), Positives = 77/183 (42%), Gaps = 18/183 (9%)
Query: 316 TSYLIIRKAKSEN-LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPN----FVKSASN 370
T L I+ ++E+ L N++C+ + T+Q + +++P+ F +
Sbjct: 189 TGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFEHRKAM 248
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
GQ L CK P P + W K+ + L ++ F K T T LLI N+ S
Sbjct: 249 AGQRVELPCKALGHPEPDYRWLKDNMPLELS------GRFQK----TVTG-LLIENIRPS 297
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQS 488
D GSY C N G + +L V +S V + S V+L V G + S
Sbjct: 298 DSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS 357
Query: 489 WYR 491
WYR
Sbjct: 358 WYR 360
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
Query: 260 PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL---T 316
PA I + S V +D VL C A+G+P A +KW K P VT + +
Sbjct: 1296 PARILTFSGTVTTPWMKDIVLPCKAVGDPSPA--VKW-MKDSNGTPSLVTIDGRRSIFSN 1352
Query: 317 SYLIIRKAKSENLGNFQCVVNNGIGS 342
IIR K+E+ G + C+ NN GS
Sbjct: 1353 GSFIIRTVKAEDSGYYSCIANNNWGS 1378
Score = 39.1 bits (87), Expect = 0.064
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 25 MITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHS-------TTKTTDKAV 76
MIT Y P TTLA G ++++C + G P+ + W K D+ I+ +TK + V
Sbjct: 800 MITSY-PNTTLATQGQKKEMSCTAHGEKPII-VRWEKEDRIINPEMARYLVSTKEVGEEV 857
Query: 77 SAEISILTNVTDNQAQYRCEATNSATE 103
+ + IL V ++ + C A NS E
Sbjct: 858 ISTLQILPTVREDSGFFSCHAINSYGE 884
Score = 33.9 bits (74), Expect = 2.4
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 159 PVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI 218
P+ AP T S + +++ +A G+P S W KD G I
Sbjct: 1291 PLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDP-SPAVKWMKDSNGTPSLVTIDGRRSI 1349
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYP 260
S GS + T + D+G Y+C A N+ G+ +++ V P
Sbjct: 1350 FSNGSFIIRT-VKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1390
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 93.9 bits (223), Expect = 2e-18
Identities = 99/405 (24%), Positives = 166/405 (40%), Gaps = 39/405 (9%)
Query: 154 WRDGIPVQNAP--IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSS 210
+RD I + N P I S+N E + S RA G+P P+I+ W ++G I +
Sbjct: 198 FRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAIS--WFRNGKLIEE-- 253
Query: 211 YSSGNDRIISEGSMLNMT--KLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ 268
N++ I +GS +T + D G Y C A N G + V I + +
Sbjct: 254 ----NEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQL-K 308
Query: 269 NVVANPNEDAVLSCTAIGNPLLAEHIKWER--------KGYKIDPKSVTFEPKNLTSYLI 320
N N L C A G P+ I W+R +G K + + ++ +S L
Sbjct: 309 NETTYENGQVTLVCDAEGEPI--PEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLH 366
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCK 380
I+ K + G + C + IG K + L +++ P+ ++ S G + C
Sbjct: 367 IKDVKLSDSGRYDCEAASRIGGHQKS-MYLDIEYAPKFISNQTIYYSWE--GNPINISCD 423
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
KS P S W ++ + LP +T K +L I + +D+G Y C A
Sbjct: 424 VKSNPPASIHWRRDKLVLPAKNTTNL-----KTYSTGRKMILEIAPTSDNDFGRYNCTAT 478
Query: 441 NELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVF 498
N +G L + P + + ++ +T + + P GG+ Y++ ++V
Sbjct: 479 NHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVA 538
Query: 499 DDSYKYEDVLPKHA--TNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ +K ++ H T ++ LE NT Y V A+N GQ Y
Sbjct: 539 SEIWK---IVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQGDY 580
Score = 73.3 bits (172), Expect = 3e-12
Identities = 70/248 (28%), Positives = 108/248 (43%), Gaps = 15/248 (6%)
Query: 225 LNMTKLTRHDAGIYTCEA-VNSQGAA-VANISVSVHYPAGIK--SVSQNVVANPNEDAVL 280
L + + + D GIY CE V ++G +I V V+ P I S N A E+
Sbjct: 171 LQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTF 230
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
SC A G+P A I W R G K+ ++ + K + L +R + + G + C N
Sbjct: 231 SCRASGSPEPA--ISWFRNG-KLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKA 287
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK--NGVKL 398
G KQ L V +P + N ++ GQV L+C + P P TW + +G
Sbjct: 288 GEDEKQ-AFLQVFVQPHIIQLKN--ETTYENGQV-TLVCDAEGEPIPEITWKRAVDGFTF 343
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ K H +S L I +V SD G Y+C A + +G ++ LD+ AP
Sbjct: 344 TEGDKSLDGRIEVKGQH--GSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAP 401
Query: 459 DQVVSLTV 466
+ + T+
Sbjct: 402 KFISNQTI 409
Score = 64.5 bits (150), Expect = 1e-09
Identities = 67/292 (22%), Positives = 112/292 (38%), Gaps = 23/292 (7%)
Query: 197 YTWTKDGLPITQSSYSSGNDRIIS--------EG--SMLNMTKLTRHDAGIYTCEAVNSQ 246
+T T G P + Y+ ++IIS EG S L + DAGIY C+A +++
Sbjct: 40 FTCTAIGEPESIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRCQATDAK 99
Query: 247 GAAV-ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G A + + ++ + V EDA + C +P A + W ++
Sbjct: 100 GQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSP--APAVSWLYHNEEVTT 157
Query: 306 KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN-NGIGSATKQDVMLIVKFKPEMDTSPNF 364
S + L I + G ++C G +D+++IV P +
Sbjct: 158 ISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKS 217
Query: 365 VKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLI 424
+ + G+ C+ P P+ +W +NG KL + + KY + + L +
Sbjct: 218 FNATAERGEEMTFSCRASGSPEPAISWFRNG-KL-IEENEKYILKGSNTE-------LTV 268
Query: 425 NNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTL 476
N+ SD G Y C A N+ G L V P + T + VTL
Sbjct: 269 RNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYENGQVTL 320
Score = 49.2 bits (112), Expect = 6e-05
Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQY 93
T G +C ++G +P ++WF+N K I K K + E+++ + + Y
Sbjct: 221 TAERGEEMTFSCRASG-SPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPY 279
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSW 153
C ATN A E + L V P ++++ E + G + TL+CD A P ++W
Sbjct: 280 VCRATNKAGEDE--KQAFLQVFVQPHIIQLKNE-TTYENG-QVTLVCD-AEGEPIPEITW 334
Query: 154 WR 155
R
Sbjct: 335 KR 336
Score = 35.5 bits (78), Expect = 0.79
Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 8/122 (6%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFK-NDKKIHSTTKTT--DKAVSAEISILTNVTDNQA 91
L+ G + C + G P ++ W+ +KI ST + + V + ++I ++
Sbjct: 32 LSVGESKFFTCTAIG-EP-ESIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAG 89
Query: 92 QYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATL 151
YRC+AT++ + TV L ++ +V P K G +A ++C SS+P +
Sbjct: 90 IYRCQATDAKGQTQE-ATVVLEIYQKLTFREV-VSPQEFKQGEDAEVVC-RVSSSPAPAV 146
Query: 152 SW 153
SW
Sbjct: 147 SW 148
Score = 32.7 bits (71), Expect = 5.5
Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 12/146 (8%)
Query: 51 NPLATLTWFKNDKKIHSTTKTTDKAVSAE--ISILTNVTDNQAQYRCEATNSATEIPLFE 108
+P ++W +++++ +T A+ A + IL ++ YRCE A F
Sbjct: 141 SPAPAVSWLYHNEEV-TTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFR 199
Query: 109 TVTLNVHFAPE-AVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFD 167
+ + V+ P ++ ++ + G E T C AS +P +SW+R+G + +
Sbjct: 200 DIIVIVNVPPAISMPQKSFNATAERGEEMTFSC-RASGSPEPAISWFRNG------KLIE 252
Query: 168 DTTSYNTVGIENEPLIIS-VRADGNP 192
+ Y G E + + + +DG P
Sbjct: 253 ENEKYILKGSNTELTVRNIINSDGGP 278
Score = 32.3 bits (70), Expect = 7.3
Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 17/141 (12%)
Query: 33 TTLAAGTVQKLACISTGGNPLATLTWFK---------NDKKIHSTTKTTDKAVSAEISIL 83
TT G V L C G P+ +TW + DK + + + S+ + I
Sbjct: 311 TTYENGQVT-LVC-DAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIK 368
Query: 84 TNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSA 143
+ +Y CEA + +++ L++ +AP+ + + + G + CD
Sbjct: 369 DVKLSDSGRYDCEAASRIGGHQ--KSMYLDIEYAPKFISNQTIYYSWE-GNPINISCD-V 424
Query: 144 SSNPPATLSWWRDG--IPVQN 162
SNPPA++ W RD +P +N
Sbjct: 425 KSNPPASIHWRRDKLVLPAKN 445
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 92.7 bits (220), Expect = 5e-18
Identities = 107/415 (25%), Positives = 169/415 (40%), Gaps = 32/415 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + T N V E + RA+GNP P I+ W +G+PI + + +
Sbjct: 349 VRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNPKPRIS--WLTNGVPI-EIAPDDPSR 404
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV--HYPAGIKSVSQNVVANP 274
+I +G + + + + +Y C A N G +AN V+V P + +
Sbjct: 405 KI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIA 462
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N A+L C G+PL I+W KG K + L I A+ ++ G + C
Sbjct: 463 NRPALLDCAFFGSPLPT--IEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 519
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WS 392
V N +G A K +V L +K + P + + G + CK K S T W
Sbjct: 520 VARNKLGMA-KNEVHLEIKDPTWIVKQPEY--AVVQRGSMVSFECKVKHDHTLSLTVLWL 576
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ +LP S + F DH L++ +V+ D G+Y C A L + + L
Sbjct: 577 KDNRELP---SDERFTV--DKDH------LVVADVSDDDSGTYTCVANTTLDSVSASAVL 625
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V P+ L +T+ +V L W PG D + + I Y +
Sbjct: 626 SVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVS 685
Query: 512 ATNFTVH-GLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTE 565
T T L +Y F VMA+N IG+S P + LT + + + + E
Sbjct: 686 GTQTTAQLKLSPYVNYSFRVMAVNSIGKS--LPSEASEQYLTKASEPDKNPTAVE 738
Score = 71.3 bits (167), Expect = 1e-11
Identities = 101/427 (23%), Positives = 163/427 (38%), Gaps = 46/427 (10%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVT--DNQA 91
TL +G L C G P + W N + ++ + ++ ++ +NV D +
Sbjct: 150 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDL-YFSNVLPEDTRE 208
Query: 92 QYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSN--PPA 149
Y C A + T+ T+ + + + V D + + T + SS PP
Sbjct: 209 DYICYARFNHTQ-----TIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPT 263
Query: 150 TLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDG-LPITQ 208
L+ P NA N + L + A+G P I Y +DG LP +
Sbjct: 264 FLT------PEGNAS--------NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNR 309
Query: 209 SSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ 268
+ Y + L + ++ D+G Y C A N+ GA ISV V + Q
Sbjct: 310 TVYKNFE-------KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQ 362
Query: 269 NVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
N+V +P ED L C A GNP I W G I+ K +I + +
Sbjct: 363 NLVLSPGEDGTLICRANGNP--KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 420
Query: 329 LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
+QC +N G + ++ P + T N + + L C P P+
Sbjct: 421 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVI-ANRPALLDCAFFGSPLPT 479
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD-YGSYECGARNELGFST 447
W K G K + H++ ++ + + L VA D G+Y C ARN+LG +
Sbjct: 480 IEWFK-GAK---------GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAK 529
Query: 448 TTVKLDV 454
V L++
Sbjct: 530 NEVHLEI 536
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 10/87 (11%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V L C + +P P W+K LP N + +KN + L I +V+ +D
Sbjct: 279 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTV------YKN----FEKTLQIIHVSEAD 328
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAP 458
G+Y+C A+N LG T+ + V +AP
Sbjct: 329 SGNYQCIAKNALGAIHHTISVRVKAAP 355
Score = 39.9 bits (89), Expect = 0.037
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 11/181 (6%)
Query: 227 MTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVS-QNVVANPNEDAVLSCTAI 285
M K R AG Q + + + + P I S ++ + +P E+ V+ C A
Sbjct: 6 MPKKKRLSAGRVPLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAK 65
Query: 286 GNPLLAEHIKWERKG--YKIDPKS-VTFEPKNLTSYL-IIRKAKSENL-GNFQCVVNNGI 340
G P W R G + ID VT +P T + I+ + K+E G +QC N
Sbjct: 66 GKP--PPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNER 123
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCK-SVPAPSFTWSKNGV-KL 398
G+A ++++ P + T GQ L C+ +P P W N +L
Sbjct: 124 GAAVSNNIVVRPSRSP-LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRL 182
Query: 399 P 399
P
Sbjct: 183 P 183
Score = 38.7 bits (86), Expect = 0.084
Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 21/155 (13%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV----L 508
V SAP SL + N T ++TLEW P G+ + Y ++Y+ + + +++ + +
Sbjct: 935 VPSAPS---SLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPI-NSTHELGPLVDLKI 990
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVE 568
P + T +T+ L +T Y F A G ++ TT+ + ++T+
Sbjct: 991 PTNKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA-VTTVDEAMASRQVDIATQG-- 1047
Query: 569 TPDISKPVIVYVSLTGAVLVLINVALIACFVWKRR 603
++ L AV +LI + LI CF+ + +
Sbjct: 1048 ---------WFIGLMCAVALLILILLIVCFIRRNK 1073
Score = 36.7 bits (81), Expect = 0.34
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
+ C+ K P PSF+W++NG ++ K T ++ A + G Y+
Sbjct: 60 IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM---KPGTGTLIINIMSEGKAETYEGVYQ 116
Query: 437 CGARNELG 444
C ARNE G
Sbjct: 117 CTARNERG 124
Score = 35.1 bits (77), Expect = 1.0
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGL-------PITQSSYSSGN--DRIISEGSMLNMTKL 230
E ++I A G PP +++WT++G P+ +G I+SEG K
Sbjct: 56 ENIVIQCEAKGKPPP-SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG------KA 108
Query: 231 TRHDAGIYTCEAVNSQGAAVANISV--SVHYPAGIKSVSQNVVANPNEDAVLSC-TAIGN 287
++ G+Y C A N +GAAV+N V P K + + + VL C IG
Sbjct: 109 ETYE-GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 167
Query: 288 P 288
P
Sbjct: 168 P 168
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 92.7 bits (220), Expect = 5e-18
Identities = 107/415 (25%), Positives = 169/415 (40%), Gaps = 32/415 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + T N V E + RA+GNP P I+ W +G+PI + + +
Sbjct: 349 VRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNPKPRIS--WLTNGVPI-EIAPDDPSR 404
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV--HYPAGIKSVSQNVVANP 274
+I +G + + + + +Y C A N G +AN V+V P + +
Sbjct: 405 KI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIA 462
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N A+L C G+PL I+W KG K + L I A+ ++ G + C
Sbjct: 463 NRPALLDCAFFGSPLPT--IEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 519
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WS 392
V N +G A K +V L +K + P + + G + CK K S T W
Sbjct: 520 VARNKLGMA-KNEVHLEIKDATWIVKQPEY--AVVQRGSMVSFECKVKHDHTLSLTVLWL 576
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ +LP S + F DH L++ +V+ D G+Y C A L + + L
Sbjct: 577 KDNRELP---SDERFTV--DKDH------LVVADVSDDDSGTYTCVANTTLDSVSASAVL 625
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V P+ L +T+ +V L W PG D + + I Y +
Sbjct: 626 SVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVS 685
Query: 512 ATNFTVH-GLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTE 565
T T L +Y F VMA+N IG+S P + LT + + + + E
Sbjct: 686 GTQTTAQLKLSPYVNYSFRVMAVNSIGKS--LPSEASEQYLTKASEPDKNPTAVE 738
Score = 72.5 bits (170), Expect = 6e-12
Identities = 102/430 (23%), Positives = 164/430 (38%), Gaps = 46/430 (10%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVT--DNQA 91
TL +G L C G P + W N + ++ + ++ ++ +NV D +
Sbjct: 150 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDL-YFSNVLPEDTRE 208
Query: 92 QYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSN--PPA 149
Y C A + T+ T+ + + + V D + + T + SS PP
Sbjct: 209 DYICYARFNHTQ-----TIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPT 263
Query: 150 TLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDG-LPITQ 208
L+ P NA N + L + A+G P I Y +DG LP +
Sbjct: 264 FLT------PEGNAS--------NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNR 309
Query: 209 SSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ 268
+ Y + L + ++ D+G Y C A N+ GA ISV V + Q
Sbjct: 310 TVYKNFE-------KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQ 362
Query: 269 NVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
N+V +P ED L C A GNP I W G I+ K +I + +
Sbjct: 363 NLVLSPGEDGTLICRANGNP--KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 420
Query: 329 LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
+QC +N G + ++ P + T N + + L C P P+
Sbjct: 421 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVI-ANRPALLDCAFFGSPLPT 479
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD-YGSYECGARNELGFST 447
W K G K + H++ ++ + + L VA D G+Y C ARN+LG +
Sbjct: 480 IEWFK-GAK---------GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAK 529
Query: 448 TTVKLDVTSA 457
V L++ A
Sbjct: 530 NEVHLEIKDA 539
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 10/87 (11%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V L C + +P P W+K LP N + +KN + L I +V+ +D
Sbjct: 279 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTV------YKN----FEKTLQIIHVSEAD 328
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAP 458
G+Y+C A+N LG T+ + V +AP
Sbjct: 329 SGNYQCIAKNALGAIHHTISVRVKAAP 355
Score = 39.9 bits (89), Expect = 0.037
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 11/181 (6%)
Query: 227 MTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVS-QNVVANPNEDAVLSCTAI 285
M K R AG Q + + + + P I S ++ + +P E+ V+ C A
Sbjct: 6 MPKKKRLSAGRVPLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAK 65
Query: 286 GNPLLAEHIKWERKG--YKIDPKS-VTFEPKNLTSYL-IIRKAKSENL-GNFQCVVNNGI 340
G P W R G + ID VT +P T + I+ + K+E G +QC N
Sbjct: 66 GKP--PPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNER 123
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCK-SVPAPSFTWSKNGV-KL 398
G+A ++++ P + T GQ L C+ +P P W N +L
Sbjct: 124 GAAVSNNIVVRPSRSP-LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRL 182
Query: 399 P 399
P
Sbjct: 183 P 183
Score = 36.7 bits (81), Expect = 0.34
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
+ C+ K P PSF+W++NG ++ K T ++ A + G Y+
Sbjct: 60 IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM---KPGTGTLIINIMSEGKAETYEGVYQ 116
Query: 437 CGARNELG 444
C ARNE G
Sbjct: 117 CTARNERG 124
Score = 35.1 bits (77), Expect = 1.0
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGL-------PITQSSYSSGN--DRIISEGSMLNMTKL 230
E ++I A G PP +++WT++G P+ +G I+SEG K
Sbjct: 56 ENIVIQCEAKGKPPP-SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG------KA 108
Query: 231 TRHDAGIYTCEAVNSQGAAVANISV--SVHYPAGIKSVSQNVVANPNEDAVLSC-TAIGN 287
++ G+Y C A N +GAAV+N V P K + + + VL C IG
Sbjct: 109 ETYE-GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 167
Query: 288 P 288
P
Sbjct: 168 P 168
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 92.7 bits (220), Expect = 5e-18
Identities = 100/381 (26%), Positives = 156/381 (40%), Gaps = 28/381 (7%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
+A+G P TY W K+G P+ DRI E LN+T + DAG+Y C A N
Sbjct: 338 KANGRPKP-TYKWLKNGEPLLT------RDRIQIEQGTLNITIVNLSDAGMYQCLAENKH 390
Query: 247 GAAVANISVSVHY--PAGIKSVSQNV-VANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI 303
G +N +SV P +++ + V + + V+ C +P K R K
Sbjct: 391 GVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKE 450
Query: 304 DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPN 363
+ + E NL II KS+ G++ C+ N G+A+ L+VK + P+
Sbjct: 451 NERITISEDGNLR---IINVTKSD-AGSYTCIATNHFGTASSTG-NLVVKDPTRVMVPPS 505
Query: 364 FVKSASNVGQVGRLMCKCKSVPAPS--FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
+ VG+ L C+ + FTWS NG + + +F D
Sbjct: 506 SMD--VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDS---AGD 560
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L+I N+ G Y C + + + L V P ++T+ +T +T L W PG
Sbjct: 561 LMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPG 620
Query: 482 FDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK----HATNFTVHGLEKNTDYIFSVMAINKI 536
D + Y I+ R F ++ +P+ TV GL +Y F +A N I
Sbjct: 621 PDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVI 680
Query: 537 GQSK-YRPDDTKATTLTSSEV 556
G + RP + + T EV
Sbjct: 681 GIGEPSRPSEKRRTEEALPEV 701
Score = 53.2 bits (122), Expect = 4e-06
Identities = 67/265 (25%), Positives = 111/265 (41%), Gaps = 30/265 (11%)
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA-NISVSVHYPAGIKSVSQNVVA-NPNE 276
+ EGS+L DAG Y C A NS G V+ + Y K+ +++ V+ +
Sbjct: 79 VVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQ 138
Query: 277 DAVLSC--TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
VL C L I E Y+ + + V+ E T L I K + ++GN+ C
Sbjct: 139 GMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQE----TGNLYIAKVEKSDVGNYTC 194
Query: 335 VVNNGI------GSATK---QDVMLIVKFKPEMDTS-PNFVKSASNVGQVGRLMCKCKSV 384
VV N + G T ++ ++ +++P+++ P V +A G +L C
Sbjct: 195 VVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAK--GATVKLECFALGN 252
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ W + K P+ A HK++ +L I N D G YEC A N G
Sbjct: 253 PVPTIIWRRADGK-PIARK----ARRHKSN-----GILEIPNFQQEDAGLYECVAENSRG 302
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNV 469
+ +L + P+ + + +V
Sbjct: 303 KNVARGQLTFYAQPNWIQKINDIHV 327
Score = 52.0 bits (119), Expect = 8e-06
Identities = 72/285 (25%), Positives = 101/285 (35%), Gaps = 37/285 (12%)
Query: 190 GNPP---SITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNS- 245
G PP ++Y W + P SY + E L + K+ + D G YTC N+
Sbjct: 145 GPPPHSGELSYAWIFNEYP----SYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTV 200
Query: 246 ---------QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTAIGNPLLAEHIK 295
+ N V Y I+ V V L C A+GNP+ I
Sbjct: 201 TNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPT--II 258
Query: 296 WERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
W R K + N L I + E+ G ++CV N G + L +
Sbjct: 259 WRRADGKPIARKARRHKSN--GILEIPNFQQEDAGLYECVAENSRGKNVARG-QLTFYAQ 315
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P N + A CK P P++ W KNG P+ T + E
Sbjct: 316 PNWIQKINDIHVAMEENVFWE--CKANGRPKPTYKWLKNGE--PLLTRDRIQIE------ 365
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS-APD 459
L I V SD G Y+C A N+ G + +L V + PD
Sbjct: 366 ---QGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPD 407
Score = 51.2 bits (117), Expect = 1e-05
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 13/165 (7%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI-ISEGSMLNMTKLTRHDAGIYTC 240
++I + +P + YTW K G I + N+RI ISE L + +T+ DAG YTC
Sbjct: 425 VVIECKPKASPKPV-YTWKK-GRDILKE-----NERITISEDGNLRIINVTKSDAGSYTC 477
Query: 241 EAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
A N G A + ++ V P + ++ E VL C + L W G
Sbjct: 478 IATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNG 537
Query: 301 YKI--DPKSVTFE---PKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
+ I D FE ++ L+IR + ++ G + C+V +
Sbjct: 538 HLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSV 582
Score = 36.3 bits (80), Expect = 0.45
Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
+L C+ K P P W NG + +Y + S+L+ N T D G+Y
Sbjct: 47 KLNCEVKGNPKPHIRWKLNGTDVDTGMDFRY--------SVVEGSLLINNPNKTQDAGTY 98
Query: 436 ECGARNELG 444
+C A N G
Sbjct: 99 QCTATNSFG 107
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 92.7 bits (220), Expect = 5e-18
Identities = 100/381 (26%), Positives = 156/381 (40%), Gaps = 28/381 (7%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
+A+G P TY W K+G P+ DRI E LN+T + DAG+Y C A N
Sbjct: 338 KANGRPKP-TYKWLKNGEPLLT------RDRIQIEQGTLNITIVNLSDAGMYQCLAENKH 390
Query: 247 GAAVANISVSVHY--PAGIKSVSQNV-VANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI 303
G +N +SV P +++ + V + + V+ C +P K R K
Sbjct: 391 GVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKE 450
Query: 304 DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPN 363
+ + E NL II KS+ G++ C+ N G+A+ L+VK + P+
Sbjct: 451 NERITISEDGNLR---IINVTKSD-AGSYTCIATNHFGTASSTG-NLVVKDPTRVMVPPS 505
Query: 364 FVKSASNVGQVGRLMCKCKSVPAPS--FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
+ VG+ L C+ + FTWS NG + + +F D
Sbjct: 506 SMD--VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDS---AGD 560
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L+I N+ G Y C + + + L V P ++T+ +T +T L W PG
Sbjct: 561 LMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPG 620
Query: 482 FDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK----HATNFTVHGLEKNTDYIFSVMAINKI 536
D + Y I+ R F ++ +P+ TV GL +Y F +A N I
Sbjct: 621 PDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVI 680
Query: 537 GQSK-YRPDDTKATTLTSSEV 556
G + RP + + T EV
Sbjct: 681 GIGEPSRPSEKRRTEEALPEV 701
Score = 53.2 bits (122), Expect = 4e-06
Identities = 67/265 (25%), Positives = 111/265 (41%), Gaps = 30/265 (11%)
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA-NISVSVHYPAGIKSVSQNVVA-NPNE 276
+ EGS+L DAG Y C A NS G V+ + Y K+ +++ V+ +
Sbjct: 79 VVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQ 138
Query: 277 DAVLSC--TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
VL C L I E Y+ + + V+ E T L I K + ++GN+ C
Sbjct: 139 GMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQE----TGNLYIAKVEKSDVGNYTC 194
Query: 335 VVNNGI------GSATK---QDVMLIVKFKPEMDTS-PNFVKSASNVGQVGRLMCKCKSV 384
VV N + G T ++ ++ +++P+++ P V +A G +L C
Sbjct: 195 VVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAK--GATVKLECFALGN 252
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ W + K P+ A HK++ +L I N D G YEC A N G
Sbjct: 253 PVPTIIWRRADGK-PIARK----ARRHKSN-----GILEIPNFQQEDAGLYECVAENSRG 302
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNV 469
+ +L + P+ + + +V
Sbjct: 303 KNVARGQLTFYAQPNWIQKINDIHV 327
Score = 52.0 bits (119), Expect = 8e-06
Identities = 72/285 (25%), Positives = 101/285 (35%), Gaps = 37/285 (12%)
Query: 190 GNPP---SITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNS- 245
G PP ++Y W + P SY + E L + K+ + D G YTC N+
Sbjct: 145 GPPPHSGELSYAWIFNEYP----SYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTV 200
Query: 246 ---------QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTAIGNPLLAEHIK 295
+ N V Y I+ V V L C A+GNP+ I
Sbjct: 201 TNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPT--II 258
Query: 296 WERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
W R K + N L I + E+ G ++CV N G + L +
Sbjct: 259 WRRADGKPIARKARRHKSN--GILEIPNFQQEDAGLYECVAENSRGKNVARG-QLTFYAQ 315
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P N + A CK P P++ W KNG P+ T + E
Sbjct: 316 PNWIQKINDIHVAMEENVFWE--CKANGRPKPTYKWLKNGE--PLLTRDRIQIE------ 365
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS-APD 459
L I V SD G Y+C A N+ G + +L V + PD
Sbjct: 366 ---QGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPD 407
Score = 51.2 bits (117), Expect = 1e-05
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 13/165 (7%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI-ISEGSMLNMTKLTRHDAGIYTC 240
++I + +P + YTW K G I + N+RI ISE L + +T+ DAG YTC
Sbjct: 425 VVIECKPKASPKPV-YTWKK-GRDILKE-----NERITISEDGNLRIINVTKSDAGSYTC 477
Query: 241 EAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
A N G A + ++ V P + ++ E VL C + L W G
Sbjct: 478 IATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNG 537
Query: 301 YKI--DPKSVTFE---PKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
+ I D FE ++ L+IR + ++ G + C+V +
Sbjct: 538 HLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSV 582
Score = 36.3 bits (80), Expect = 0.45
Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
+L C+ K P P W NG + +Y + S+L+ N T D G+Y
Sbjct: 47 KLNCEVKGNPKPHIRWKLNGTDVDTGMDFRY--------SVVEGSLLINNPNKTQDAGTY 98
Query: 436 ECGARNELG 444
+C A N G
Sbjct: 99 QCTATNSFG 107
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 91.5 bits (217), Expect = 1e-17
Identities = 75/278 (26%), Positives = 122/278 (43%), Gaps = 21/278 (7%)
Query: 181 PLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTC 240
P++++ + G P T +W+K G + + G+ +S L + + AG YTC
Sbjct: 4 PVVLTCHSTGIPAP-TVSWSKAGAQLG----ARGSGYRVSPSGALEIGQALPIHAGRYTC 58
Query: 241 EAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
A NS G A ++ ++V +K + V A E+ +L C A G P I W+++G
Sbjct: 59 SARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIP--RPTITWQKEG 116
Query: 301 YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDT 360
+ T L I A E+ GN+ C+ N GSA + L+V+ P ++
Sbjct: 117 LNVATGVSTQVLPG--GQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQVPPVIEN 173
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
++ G L CK + P P+ TW K+G PV+ + F I +
Sbjct: 174 G--LPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQ--PVSGAEGKFT-------IQPSG 222
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
LL+ N+ D G+Y C A N +G + V L + P
Sbjct: 223 ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP 260
Score = 78.2 bits (184), Expect = 1e-13
Identities = 58/237 (24%), Positives = 101/237 (42%), Gaps = 13/237 (5%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ VQ +P+ S + E +++ A G P T TW K+GL + ++G
Sbjct: 73 LTVQASPVVKPLPSV-VRAVAEEEVLLPCEASGIPRP-TITWQKEGLNV-----ATGVST 125
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
+ G L + + DAG Y C A NS G+A+ + V P I++ ++
Sbjct: 126 QVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSH 185
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
A L C A G+P +I W++ G + F + + L+++ + ++ G + C
Sbjct: 186 AFLPCKARGSP--EPNITWDKDGQPVSGAEGKFTIQP-SGELLVKNLEGQDAGTYTCTAE 242
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKN 394
N +G A ++ V L + P T P + +G L C + P P W+ N
Sbjct: 243 NAVGRARRR-VHLTILVLPVFTTLPG--DRSLRLGDRLWLRCAARGSPTPRIGWTVN 296
Score = 37.9 bits (84), Expect = 0.15
Identities = 36/122 (29%), Positives = 56/122 (45%), Gaps = 13/122 (10%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA- 101
L C STG P T++W K ++ + + S + I + + +Y C A NSA
Sbjct: 7 LTCHSTG-IPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 65
Query: 102 -TEIPLFETVTLN--VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGI 158
+F TV + V P V+ AE +VL P C+ AS P T++W ++G+
Sbjct: 66 VAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLP-------CE-ASGIPRPTITWQKEGL 117
Query: 159 PV 160
V
Sbjct: 118 NV 119
Score = 37.1 bits (82), Expect = 0.26
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 7/135 (5%)
Query: 30 VPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN 89
+P A + L G P T+TW K + +T +T ++ I ++
Sbjct: 84 LPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNV-ATGVSTQVLPGGQLRIAHASPED 142
Query: 90 QAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPP 148
Y C A NSA + + V P ++ PD+ G A L C A +P
Sbjct: 143 AGNYLCIAKNSAGSAMGKTRLVVQV---PPVIE-NGLPDLSTTEGSHAFLPC-KARGSPE 197
Query: 149 ATLSWWRDGIPVQNA 163
++W +DG PV A
Sbjct: 198 PNITWDKDGQPVSGA 212
>BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein.
Length = 442
Score = 91.1 bits (216), Expect = 1e-17
Identities = 79/312 (25%), Positives = 129/312 (41%), Gaps = 11/312 (3%)
Query: 136 ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSI 195
A IC + + + L + + + P F + + V + ++ DGNPP
Sbjct: 128 ADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPE 187
Query: 196 TYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
+G + S I S GS + ++K TR DAG Y C A N G + +
Sbjct: 188 IIWILPNGTRFSNGPQSY-QYLIASNGSFI-ISKTTREDAGKYRCAARNKVGYIEKLVIL 245
Query: 256 SVHYPAGIKSVSQNVVAN-PNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEP- 312
+ I + + V E L C + G P +IKW GY +D + +
Sbjct: 246 EIGQKPVILTYAPGTVKGISGESLSLHCVSDGIP--KPNIKWTMPSGYVVDRPQINGKYI 303
Query: 313 KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVG 372
+ L+I++A + + GN+ C N +G ++IV + P + P + G
Sbjct: 304 LHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPR-SIVTRTG 362
Query: 373 QVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDY 432
+L C VP P TW L ++T++K H ++ + L+I N TSD
Sbjct: 363 AAFQLHCVALGVPKPEITWEMPDHSL-LSTASK--ERTHGSEQLHLQGTLVIQNPQTSDS 419
Query: 433 GSYECGARNELG 444
G Y+C A+N LG
Sbjct: 420 GIYKCTAKNPLG 431
Score = 68.9 bits (161), Expect = 7e-11
Identities = 72/310 (23%), Positives = 125/310 (40%), Gaps = 28/310 (9%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSM 224
++ + T + + RA+G P D + +T Y G+ + +
Sbjct: 59 LYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYY--GSRITVHKNGT 116
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVSQNVVANPNEDAVL 280
L + + D+ + C A N G +V + + V P ++ +VA + L
Sbjct: 117 LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTAL 176
Query: 281 SCTAIGNPLLAEHIKW---ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
+C+ GNP I W + P+S + + S+ II K E+ G ++C
Sbjct: 177 NCSVDGNP--PPEIIWILPNGTRFSNGPQSYQYLIASNGSF-IISKTTREDAGKYRCAAR 233
Query: 338 NGIGSATKQDVMLIVKFKPEMDT-SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG- 395
N +G K V+L + KP + T +P VK S G+ L C +P P+ W+
Sbjct: 234 NKVGYIEKL-VILEIGQKPVILTYAPGTVKGIS--GESLSLHCVSDGIPKPNIKWTMPSG 290
Query: 396 --VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
V P + KY H N L+I D G+Y C A+N +G + TV +
Sbjct: 291 YVVDRP-QINGKYI--LHDN------GTLVIKEATAYDRGNYICKAQNSVGHTLITVPVM 341
Query: 454 VTSAPDQVVS 463
+ + P ++ +
Sbjct: 342 IVAYPPRITN 351
Score = 52.8 bits (121), Expect = 5e-06
Identities = 46/175 (26%), Positives = 77/175 (44%), Gaps = 13/175 (7%)
Query: 176 GIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD 234
GI E L + +DG P P+I WT + +G I+ + L + + T +D
Sbjct: 263 GISGESLSLHCVSDGIPKPNIK--WTMPSGYVVDRPQINGK-YILHDNGTLVIKEATAYD 319
Query: 235 AGIYTCEAVNSQGAAVANISVS-VHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAE 292
G Y C+A NS G + + V V YP I + +++V L C A+G P
Sbjct: 320 RGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVP--KP 377
Query: 293 HIKWERKGYKI-----DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
I WE + + ++ E +L L+I+ ++ + G ++C N +GS
Sbjct: 378 EITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 432
Score = 37.1 bits (82), Expect = 0.26
Identities = 23/49 (46%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
L IN V D G Y C ARN G T KLDV S P + L TN T
Sbjct: 17 LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGL-YTNRT 64
>BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein.
Length = 602
Score = 91.1 bits (216), Expect = 1e-17
Identities = 79/312 (25%), Positives = 129/312 (41%), Gaps = 11/312 (3%)
Query: 136 ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSI 195
A IC + + + L + + + P F + + V + ++ DGNPP
Sbjct: 288 ADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPE 347
Query: 196 TYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
+G + S I S GS + ++K TR DAG Y C A N G + +
Sbjct: 348 IIWILPNGTRFSNGPQSY-QYLIASNGSFI-ISKTTREDAGKYRCAARNKVGYIEKLVIL 405
Query: 256 SVHYPAGIKSVSQNVVAN-PNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEP- 312
+ I + + V E L C + G P +IKW GY +D + +
Sbjct: 406 EIGQKPVILTYAPGTVKGISGESLSLHCVSDGIP--KPNIKWTMPSGYVVDRPQINGKYI 463
Query: 313 KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVG 372
+ L+I++A + + GN+ C N +G ++IV + P + P + G
Sbjct: 464 LHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPR-SIVTRTG 522
Query: 373 QVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDY 432
+L C VP P TW L ++T++K H ++ + L+I N TSD
Sbjct: 523 AAFQLHCVALGVPKPEITWEMPDHSL-LSTASK--ERTHGSEQLHLQGTLVIQNPQTSDS 579
Query: 433 GSYECGARNELG 444
G Y+C A+N LG
Sbjct: 580 GIYKCTAKNPLG 591
Score = 68.5 bits (160), Expect = 9e-11
Identities = 72/310 (23%), Positives = 124/310 (40%), Gaps = 28/310 (9%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSM 224
++ T + + RA+G P D + +T Y G+ + +
Sbjct: 219 LYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYY--GSRITVHKNGT 276
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVSQNVVANPNEDAVL 280
L + + D+ + C A N G +V + + V P ++ +VA + L
Sbjct: 277 LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTAL 336
Query: 281 SCTAIGNPLLAEHIKW---ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
+C+ GNP I W + P+S + + S+ II K E+ G ++C
Sbjct: 337 NCSVDGNP--PPEIIWILPNGTRFSNGPQSYQYLIASNGSF-IISKTTREDAGKYRCAAR 393
Query: 338 NGIGSATKQDVMLIVKFKPEMDT-SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG- 395
N +G K V+L + KP + T +P VK S G+ L C +P P+ W+
Sbjct: 394 NKVGYIEKL-VILEIGQKPVILTYAPGTVKGIS--GESLSLHCVSDGIPKPNIKWTMPSG 450
Query: 396 --VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
V P + KY H N L+I D G+Y C A+N +G + TV +
Sbjct: 451 YVVDRP-QINGKYI--LHDN------GTLVIKEATAYDRGNYICKAQNSVGHTLITVPVM 501
Query: 454 VTSAPDQVVS 463
+ + P ++ +
Sbjct: 502 IVAYPPRITN 511
Score = 52.8 bits (121), Expect = 5e-06
Identities = 46/175 (26%), Positives = 77/175 (44%), Gaps = 13/175 (7%)
Query: 176 GIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD 234
GI E L + +DG P P+I WT + +G I+ + L + + T +D
Sbjct: 423 GISGESLSLHCVSDGIPKPNIK--WTMPSGYVVDRPQINGK-YILHDNGTLVIKEATAYD 479
Query: 235 AGIYTCEAVNSQGAAVANISVS-VHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAE 292
G Y C+A NS G + + V V YP I + +++V L C A+G P
Sbjct: 480 RGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVP--KP 537
Query: 293 HIKWERKGYKI-----DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
I WE + + ++ E +L L+I+ ++ + G ++C N +GS
Sbjct: 538 EITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 592
Score = 49.2 bits (112), Expect = 6e-05
Identities = 44/158 (27%), Positives = 58/158 (36%), Gaps = 16/158 (10%)
Query: 330 GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
G++ C N +G + + ++ P + S N G L C+ P P
Sbjct: 94 GDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS-NKTNKRIKAGDTAVLDCEVTGDPKPKI 152
Query: 390 TWSKNGVKLPVNTSTKYFAE---FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFS 446
W LP N + + FH N +T IN V D G Y C ARN G
Sbjct: 153 FWL-----LPSNDMISFSIDRYTFHANGSLT------INKVKLLDSGEYVCVARNPSGDD 201
Query: 447 TTTVKLDVTSAPDQVVSL-TVTNVTHSTVTLEWVPGFD 483
T KLDV S P + L T V +T FD
Sbjct: 202 TKMYKLDVVSKPPLINGLYTSRTVIKATAVRHSKKHFD 239
Score = 40.7 bits (91), Expect = 0.021
Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Query: 352 VKFKP-EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
++ KP ++D F K + G+ ++ CK P P +WS + +N + +
Sbjct: 12 LRLKPAKIDHKQYFRKQVLH-GKDFQVDCKASGSPVPEISWSLPDGTM-INNAMQADDSG 69
Query: 411 HKNDHITY--TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
H+ T L N V ++ G Y C A+N LG V L V +A ++ TN
Sbjct: 70 HRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTN 129
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 91.1 bits (216), Expect = 1e-17
Identities = 79/312 (25%), Positives = 129/312 (41%), Gaps = 11/312 (3%)
Query: 136 ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSI 195
A IC + + + L + + + P F + + V + ++ DGNPP
Sbjct: 2309 ADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPE 2368
Query: 196 TYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
+G + S I S GS + ++K TR DAG Y C A N G + +
Sbjct: 2369 IIWILPNGTRFSNGPQSY-QYLIASNGSFI-ISKTTREDAGKYRCAARNKVGYIEKLVIL 2426
Query: 256 SVHYPAGIKSVSQNVVAN-PNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEP- 312
+ I + + V E L C + G P +IKW GY +D + +
Sbjct: 2427 EIGQKPVILTYAPGTVKGISGESLSLHCVSDGIP--KPNIKWTMPSGYVVDRPQINGKYI 2484
Query: 313 KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVG 372
+ L+I++A + + GN+ C N +G ++IV + P + P + G
Sbjct: 2485 LHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPR-SIVTRTG 2543
Query: 373 QVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDY 432
+L C VP P TW L ++T++K H ++ + L+I N TSD
Sbjct: 2544 AAFQLHCVALGVPKPEITWEMPDHSL-LSTASK--ERTHGSEQLHLQGTLVIQNPQTSDS 2600
Query: 433 GSYECGARNELG 444
G Y+C A+N LG
Sbjct: 2601 GIYKCTAKNPLG 2612
Score = 76.6 bits (180), Expect = 3e-13
Identities = 75/289 (25%), Positives = 114/289 (39%), Gaps = 24/289 (8%)
Query: 184 ISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAV 243
+ RA+G P S T TW + S +++ L + L+ +D G Y C A
Sbjct: 1765 LKCRAEGRP-SPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVAS 1823
Query: 244 N--SQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE-RKG 300
N Q + + I V P ++ Q +V E L CTA G P + W G
Sbjct: 1824 NPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTP--QPSVYWVLSDG 1881
Query: 301 YKIDPKSVTFEPKNLTS--YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
++ P T L S L IR S + G ++C+ + GS ++ VML ++ E
Sbjct: 1882 TEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGS-ERRVVMLTME---ER 1937
Query: 359 DTSPNFVKSAS------NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
TSP +++AS N G L C P P W +LP
Sbjct: 1938 VTSPR-IEAASQKRTEVNFGDKLLLNCSATGEPKPQIMW-----RLPSKAVVDQQHRVGS 1991
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
H+ L I +V D G Y C ARN++G + + + P ++
Sbjct: 1992 WIHVYPNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAKI 2040
Score = 68.9 bits (161), Expect = 7e-11
Identities = 72/310 (23%), Positives = 125/310 (40%), Gaps = 28/310 (9%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSM 224
++ + T + + RA+G P D + +T Y G+ + +
Sbjct: 2240 LYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYY--GSRITVHKNGT 2297
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVSQNVVANPNEDAVL 280
L + + D+ + C A N G +V + + V P ++ +VA + L
Sbjct: 2298 LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTAL 2357
Query: 281 SCTAIGNPLLAEHIKW---ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
+C+ GNP I W + P+S + + S+ II K E+ G ++C
Sbjct: 2358 NCSVDGNP--PPEIIWILPNGTRFSNGPQSYQYLIASNGSF-IISKTTREDAGKYRCAAR 2414
Query: 338 NGIGSATKQDVMLIVKFKPEMDT-SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG- 395
N +G K V+L + KP + T +P VK S G+ L C +P P+ W+
Sbjct: 2415 NKVGYIEKL-VILEIGQKPVILTYAPGTVKGIS--GESLSLHCVSDGIPKPNIKWTMPSG 2471
Query: 396 --VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
V P + KY H N L+I D G+Y C A+N +G + TV +
Sbjct: 2472 YVVDRP-QINGKYI--LHDN------GTLVIKEATAYDRGNYICKAQNSVGHTLITVPVM 2522
Query: 454 VTSAPDQVVS 463
+ + P ++ +
Sbjct: 2523 IVAYPPRITN 2532
Score = 68.1 bits (159), Expect = 1e-10
Identities = 75/312 (24%), Positives = 128/312 (41%), Gaps = 32/312 (10%)
Query: 175 VGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD 234
VG E L + A G P Y DG + +++ + S G+ L + L D
Sbjct: 1853 VGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGT-LYIRNLASSD 1911
Query: 235 AGIYTCEAVNSQGAAVANISVSVHYPAG---IKSVSQN-VVANPNEDAVLSCTAIGNPLL 290
G Y C A +S G+ + +++ I++ SQ N + +L+C+A G P
Sbjct: 1912 RGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEP-- 1969
Query: 291 AEHIKWERKGYKIDPKSVTFEPKNLTSY--------LIIRKAKSENLGNFQCVVNNGIGS 342
I W ++ K+V + + S+ L I ++ G + CV N +G
Sbjct: 1970 KPQIMW-----RLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMGD 2024
Query: 343 ATKQDVMLI---VKFKP-EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
D++L+ ++ KP ++D F K + G+ ++ CK P P +WS +
Sbjct: 2025 ----DLILMHVSLRLKPAKIDHKQYFRKQVLH-GKDFQVDCKASGSPVPEISWSLPDGTM 2079
Query: 399 PVNTSTKYFAEFHKNDHITY--TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+N + + H+ T L N V ++ G Y C A+N LG V L V +
Sbjct: 2080 -INNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVIT 2138
Query: 457 APDQVVSLTVTN 468
A ++ TN
Sbjct: 2139 AAPRIRQSNKTN 2150
Score = 65.7 bits (153), Expect = 6e-10
Identities = 54/205 (26%), Positives = 91/205 (44%), Gaps = 15/205 (7%)
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTS-YLI 320
G K+ S + AN DA L C A+GNPL H G + + + L + L
Sbjct: 1652 GGKAASFTIPAN--SDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLS 1709
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP---EMDTSPNFVKSASNVGQVGRL 377
I++ + ++ G + C +N G+ + +V + P E T V S S V L
Sbjct: 1710 IQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTV----EL 1765
Query: 378 MCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
C+ + P+P+ TW L T ++ + +T L+++N++ D G Y+C
Sbjct: 1766 KCRAEGRPSPTVTWI-----LANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKC 1820
Query: 438 GARNELGFSTTTVKLDVTSAPDQVV 462
A N G + VK+ V +AP ++
Sbjct: 1821 VASNPGGQDSLLVKIQVIAAPPVIL 1845
Score = 63.3 bits (147), Expect = 3e-09
Identities = 66/280 (23%), Positives = 113/280 (40%), Gaps = 16/280 (5%)
Query: 179 NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
N + A GNP P+I +T GL +++ +S +++ G+ L++ ++ D G
Sbjct: 1663 NSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNS-RVQVLPNGT-LSIQRVEIQDRGQ 1720
Query: 238 YTCEAVNSQGAAVANISVS-VHYPAGI-KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
Y C A N G ++++S V YP I + ++ + + L C A G P + +
Sbjct: 1721 YLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRP--SPTVT 1778
Query: 296 WERKGYKIDPKSVTFEPKNLTSY---LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
W + +S + + + L++ + G ++CV +N G V + V
Sbjct: 1779 WILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNP-GGQDSLLVKIQV 1837
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + G+ +L C K P PS W L T K +
Sbjct: 1838 IAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYW-----VLSDGTEVKPLQFTNS 1892
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
+ L I N+A+SD G+YEC A + G V L
Sbjct: 1893 KLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVML 1932
Score = 62.9 bits (146), Expect = 5e-09
Identities = 78/307 (25%), Positives = 115/307 (37%), Gaps = 34/307 (11%)
Query: 180 EPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
+ L+++ A G P P I W + + G+ + L + +T D+G+Y
Sbjct: 1957 DKLLLNCSATGEPKPQIM--WRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVY 2014
Query: 239 TCEAVNSQGAAVANISVSVHY-PAGI--KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIK 295
C A N G + + VS+ PA I K + V + +D + C A G+P+ I
Sbjct: 2015 LCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLH-GKDFQVDCKASGSPV--PEIS 2071
Query: 296 WERK-GYKIDPKSVTFEPKNLT--------SYLIIRKAKSENLGNFQCVVNNGIGSATKQ 346
W G I+ + + T L K G++ C N +G +
Sbjct: 2072 WSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMK 2131
Query: 347 DVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
+ ++ P + S N G L C+ P P W LP N +
Sbjct: 2132 VHLTVITAAPRIRQS-NKTNKRIKAGDTAVLDCEVTGDPKPKIFWL-----LPSNDMISF 2185
Query: 407 FAE---FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
+ FH N +T IN V D G Y C ARN G T KLDV S P +
Sbjct: 2186 SIDRYTFHANGSLT------INKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLING 2239
Query: 464 LTVTNVT 470
L TN T
Sbjct: 2240 L-YTNRT 2245
Score = 52.8 bits (121), Expect = 5e-06
Identities = 46/175 (26%), Positives = 77/175 (44%), Gaps = 13/175 (7%)
Query: 176 GIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD 234
GI E L + +DG P P+I WT + +G I+ + L + + T +D
Sbjct: 2444 GISGESLSLHCVSDGIPKPNIK--WTMPSGYVVDRPQINGK-YILHDNGTLVIKEATAYD 2500
Query: 235 AGIYTCEAVNSQGAAVANISVS-VHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAE 292
G Y C+A NS G + + V V YP I + +++V L C A+G P
Sbjct: 2501 RGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVP--KP 2558
Query: 293 HIKWERKGYKI-----DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
I WE + + ++ E +L L+I+ ++ + G ++C N +GS
Sbjct: 2559 EITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 2613
Score = 35.1 bits (77), Expect = 1.0
Identities = 26/102 (25%), Positives = 40/102 (39%), Gaps = 6/102 (5%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C+ P P+ W++ L ++ + + + L I V D G Y
Sbjct: 1668 LPCEAVGNPLPTIHWTRVPSGLDLSKRKQ-----NSRVQVLPNGTLSIQRVEIQDRGQYL 1722
Query: 437 CGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT-HSTVTLE 477
C A N G V L V S P +++ +T HS T+E
Sbjct: 1723 CSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVE 1764
Score = 33.1 bits (72), Expect = 4.2
Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 5/92 (5%)
Query: 166 FDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
+ + ++TV I E L + + G P + + +W +P Y S D+ + L
Sbjct: 576 YQENGIHHTVFI-GETLDLPCHSTGIPDA-SISWV---IPGNNVLYQSSRDKKVLNNGTL 630
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVANISVSV 257
+ ++T D G Y C A N G VSV
Sbjct: 631 RILQVTPKDQGYYRCVAANPSGVDFLIFQVSV 662
>AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens
cDNA FLJ25972 fis, clone TST05664. ).
Length = 399
Score = 91.1 bits (216), Expect = 1e-17
Identities = 79/312 (25%), Positives = 129/312 (41%), Gaps = 11/312 (3%)
Query: 136 ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSI 195
A IC + + + L + + + P F + + V + ++ DGNPP
Sbjct: 85 ADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPE 144
Query: 196 TYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
+G + S I S GS + ++K TR DAG Y C A N G + +
Sbjct: 145 IIWILPNGTRFSNGPQSY-QYLIASNGSFI-ISKTTREDAGKYRCAARNKVGYIEKLVIL 202
Query: 256 SVHYPAGIKSVSQNVVAN-PNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEP- 312
+ I + + V E L C + G P +IKW GY +D + +
Sbjct: 203 EIGQKPVILTYAPGTVKGISGESLSLHCVSDGIP--KPNIKWTMPSGYVVDRPQINGKYI 260
Query: 313 KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVG 372
+ L+I++A + + GN+ C N +G ++IV + P + P + G
Sbjct: 261 LHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPR-SIVTRTG 319
Query: 373 QVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDY 432
+L C VP P TW L ++T++K H ++ + L+I N TSD
Sbjct: 320 AAFQLHCVALGVPKPEITWEMPDHSL-LSTASK--ERTHGSEQLHLQGTLVIQNPQTSDS 376
Query: 433 GSYECGARNELG 444
G Y+C A+N LG
Sbjct: 377 GIYKCTAKNPLG 388
Score = 68.9 bits (161), Expect = 7e-11
Identities = 72/310 (23%), Positives = 125/310 (40%), Gaps = 28/310 (9%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSM 224
++ + T + + RA+G P D + +T Y G+ + +
Sbjct: 16 LYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYY--GSRITVHKNGT 73
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVSQNVVANPNEDAVL 280
L + + D+ + C A N G +V + + V P ++ +VA + L
Sbjct: 74 LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTAL 133
Query: 281 SCTAIGNPLLAEHIKW---ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
+C+ GNP I W + P+S + + S+ II K E+ G ++C
Sbjct: 134 NCSVDGNP--PPEIIWILPNGTRFSNGPQSYQYLIASNGSF-IISKTTREDAGKYRCAAR 190
Query: 338 NGIGSATKQDVMLIVKFKPEMDT-SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG- 395
N +G K V+L + KP + T +P VK S G+ L C +P P+ W+
Sbjct: 191 NKVGYIEKL-VILEIGQKPVILTYAPGTVKGIS--GESLSLHCVSDGIPKPNIKWTMPSG 247
Query: 396 --VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
V P + KY H N L+I D G+Y C A+N +G + TV +
Sbjct: 248 YVVDRP-QINGKYI--LHDN------GTLVIKEATAYDRGNYICKAQNSVGHTLITVPVM 298
Query: 454 VTSAPDQVVS 463
+ + P ++ +
Sbjct: 299 IVAYPPRITN 308
Score = 52.8 bits (121), Expect = 5e-06
Identities = 46/175 (26%), Positives = 77/175 (44%), Gaps = 13/175 (7%)
Query: 176 GIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD 234
GI E L + +DG P P+I WT + +G I+ + L + + T +D
Sbjct: 220 GISGESLSLHCVSDGIPKPNIK--WTMPSGYVVDRPQINGK-YILHDNGTLVIKEATAYD 276
Query: 235 AGIYTCEAVNSQGAAVANISVS-VHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAE 292
G Y C+A NS G + + V V YP I + +++V L C A+G P
Sbjct: 277 RGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVP--KP 334
Query: 293 HIKWERKGYKI-----DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
I WE + + ++ E +L L+I+ ++ + G ++C N +GS
Sbjct: 335 EITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 389
>AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ35750 fis, clone TESTI2004539, weakly similar to
Homo sapiens adlican mRNA. ).
Length = 650
Score = 91.1 bits (216), Expect = 1e-17
Identities = 79/312 (25%), Positives = 129/312 (41%), Gaps = 11/312 (3%)
Query: 136 ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSI 195
A IC + + + L + + + P F + + V + ++ DGNPP
Sbjct: 336 ADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPE 395
Query: 196 TYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
+G + S I S GS + ++K TR DAG Y C A N G + +
Sbjct: 396 IIWILPNGTRFSNGPQSY-QYLIASNGSFI-ISKTTREDAGKYRCAARNKVGYIEKLVIL 453
Query: 256 SVHYPAGIKSVSQNVVAN-PNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEP- 312
+ I + + V E L C + G P +IKW GY +D + +
Sbjct: 454 EIGQKPVILTYAPGTVKGISGESLSLHCVSDGIP--KPNIKWTMPSGYVVDRPQINGKYI 511
Query: 313 KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVG 372
+ L+I++A + + GN+ C N +G ++IV + P + P + G
Sbjct: 512 LHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPR-SIVTRTG 570
Query: 373 QVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDY 432
+L C VP P TW L ++T++K H ++ + L+I N TSD
Sbjct: 571 AAFQLHCVALGVPKPEITWEMPDHSL-LSTASK--ERTHGSEQLHLQGTLVIQNPQTSDS 627
Query: 433 GSYECGARNELG 444
G Y+C A+N LG
Sbjct: 628 GIYKCTAKNPLG 639
Score = 68.9 bits (161), Expect = 7e-11
Identities = 72/310 (23%), Positives = 125/310 (40%), Gaps = 28/310 (9%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSM 224
++ + T + + RA+G P D + +T Y G+ + +
Sbjct: 267 LYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYY--GSRITVHKNGT 324
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVSQNVVANPNEDAVL 280
L + + D+ + C A N G +V + + V P ++ +VA + L
Sbjct: 325 LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTAL 384
Query: 281 SCTAIGNPLLAEHIKW---ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
+C+ GNP I W + P+S + + S+ II K E+ G ++C
Sbjct: 385 NCSVDGNP--PPEIIWILPNGTRFSNGPQSYQYLIASNGSF-IISKTTREDAGKYRCAAR 441
Query: 338 NGIGSATKQDVMLIVKFKPEMDT-SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG- 395
N +G K V+L + KP + T +P VK S G+ L C +P P+ W+
Sbjct: 442 NKVGYIEKL-VILEIGQKPVILTYAPGTVKGIS--GESLSLHCVSDGIPKPNIKWTMPSG 498
Query: 396 --VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
V P + KY H N L+I D G+Y C A+N +G + TV +
Sbjct: 499 YVVDRP-QINGKYI--LHDN------GTLVIKEATAYDRGNYICKAQNSVGHTLITVPVM 549
Query: 454 VTSAPDQVVS 463
+ + P ++ +
Sbjct: 550 IVAYPPRITN 559
Score = 58.4 bits (135), Expect = 1e-07
Identities = 71/268 (26%), Positives = 102/268 (38%), Gaps = 32/268 (11%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY-PAGI--KSVSQNVVANP 274
+ GS+ + +T D+G+Y C A N G + + VS+ PA I K + V +
Sbjct: 22 VYPNGSLF-IGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLH- 79
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERK-GYKIDPKSVTFEPKNLT--------SYLIIRKAK 325
+D + C A G+P+ I W G I+ + + T L K
Sbjct: 80 GKDFQVDCKASGSPV--PEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVG 137
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVP 385
G++ C N +G + + ++ P + S N G L C+ P
Sbjct: 138 VAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS-NKTNKRIKAGDTAVLDCEVTGDP 196
Query: 386 APSFTWSKNGVKLPVNTSTKYFAE---FHKNDHITYTSVLLINNVATSDYGSYECGARNE 442
P W LP N + + FH N +T IN V D G Y C ARN
Sbjct: 197 KPKIFWL-----LPSNDMISFSIDRYTFHANGSLT------INKVKLLDSGEYVCVARNP 245
Query: 443 LGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
G T KLDV S P + L TN T
Sbjct: 246 SGDDTKMYKLDVVSKPPLINGL-YTNRT 272
Score = 52.8 bits (121), Expect = 5e-06
Identities = 46/175 (26%), Positives = 77/175 (44%), Gaps = 13/175 (7%)
Query: 176 GIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD 234
GI E L + +DG P P+I WT + +G I+ + L + + T +D
Sbjct: 471 GISGESLSLHCVSDGIPKPNIK--WTMPSGYVVDRPQINGK-YILHDNGTLVIKEATAYD 527
Query: 235 AGIYTCEAVNSQGAAVANISVS-VHYPAGIKS-VSQNVVANPNEDAVLSCTAIGNPLLAE 292
G Y C+A NS G + + V V YP I + +++V L C A+G P
Sbjct: 528 RGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVP--KP 585
Query: 293 HIKWERKGYKI-----DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
I WE + + ++ E +L L+I+ ++ + G ++C N +GS
Sbjct: 586 EITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 640
>BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein.
Length = 697
Score = 90.2 bits (214), Expect = 3e-17
Identities = 99/381 (25%), Positives = 156/381 (40%), Gaps = 29/381 (7%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
+A+G P TY W K+G P+ DRI E LN+T + DAG+Y C A N
Sbjct: 10 KANGRPKP-TYKWLKNGEPLLT------RDRIQIEQGTLNITIVNLSDAGMYQCLAENKH 62
Query: 247 GAAVANISVSVHY--PAGIKSVSQNV-VANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI 303
G +N +SV P +++ + V + + V+ C +P K R K
Sbjct: 63 GVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKE 122
Query: 304 DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPN 363
+ + E NL II KS+ G++ C+ N G+A+ L+VK + P+
Sbjct: 123 NERITISEDGNLR---IINVTKSD-AGSYTCIATNHFGTASSTG-NLVVKDPTRVMVPPS 177
Query: 364 FVKSASNVGQVGRLMCKCKSVPAPS--FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
+ VG+ L C+ + FTWS NG + + +F +
Sbjct: 178 SMD--VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGDS----AGD 231
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L+I N+ G Y C + + + L V P ++T+ +T +T L W PG
Sbjct: 232 LMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPG 291
Query: 482 FDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK----HATNFTVHGLEKNTDYIFSVMAINKI 536
D + Y I+ R F ++ +P+ TV GL +Y F +A N I
Sbjct: 292 PDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVI 351
Query: 537 GQSK-YRPDDTKATTLTSSEV 556
G + RP + + T EV
Sbjct: 352 GIGEPSRPSEKRRTEEALPEV 372
Score = 51.2 bits (117), Expect = 1e-05
Identities = 46/164 (28%), Positives = 71/164 (43%), Gaps = 12/164 (7%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI-ISEGSMLNMTKLTRHDAGIYTC 240
++I + +P + YTW K G I + N+RI ISE L + +T+ DAG YTC
Sbjct: 97 VVIECKPKASPKPV-YTWKK-GRDILKE-----NERITISEDGNLRIINVTKSDAGSYTC 149
Query: 241 EAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
A N G A + ++ V P + ++ E VL C + L W G
Sbjct: 150 IATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNG 209
Query: 301 YKI--DPKSVTFEPKNLTSY--LIIRKAKSENLGNFQCVVNNGI 340
+ I D FE S L+IR + ++ G + C+V +
Sbjct: 210 HLIDFDRDGDHFERVGGDSAGDLMIRNIQLKHAGKYVCMVQTSV 253
Score = 32.7 bits (71), Expect = 5.5
Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 12/82 (14%)
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
CK P P++ W KNG P+ T + E L I V SD G Y+C
Sbjct: 9 CKANGRPKPTYKWLKNGE--PLLTRDRIQIE---------QGTLNITIVNLSDAGMYQCL 57
Query: 439 ARNELGFSTTTVKLDVTS-APD 459
A N+ G + +L V + PD
Sbjct: 58 AENKHGVIFSNAELSVIAVGPD 79
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 89.4 bits (212), Expect = 5e-17
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 27/287 (9%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ EP ++ + P T +W KDG P+ ++RI G L +T + DAG
Sbjct: 143 VVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-----DERITIRGGKLMITYTRKSDAG 197
Query: 237 IYTCEAVNSQG---AAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
Y C N G + VA ++V + P+ +K S N+ ++ A C A G+P+
Sbjct: 198 KYVCVGTNMVGERESEVAELTV-LERPSFVKRPS-NLAVTVDDSAEFKCEARGDPVPT-- 253
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
++W + ++ PKS +E ++ L IRK + ++G++ CV N +G A + L V+
Sbjct: 254 VRWRKDDGEL-PKS-RYEIRD-DHTLKIRKVTAGDMGSYTCVAENMVGKA-EASATLTVQ 309
Query: 354 FKPEMDTSPNFV-KSASNVGQVGRLM---CKCKSVPAPSFTWSKNGVKLPVNTSTKYFA- 408
E P+FV K V +GR + C+ P P+ W + G + N Y
Sbjct: 310 VGSE---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ---NLLFSYQPP 363
Query: 409 EFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVT 455
+ ++ T L I NV SD G Y C N G T L+VT
Sbjct: 364 QSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT 410
Score = 77.8 bits (183), Expect = 1e-13
Identities = 76/295 (25%), Positives = 123/295 (41%), Gaps = 28/295 (9%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSGNDRIISEGSMLNMT----KLTR 232
+ EP ++ +A+G P T W K G + T + ++ GS+ + + +R
Sbjct: 42 KGEPATLNCKAEGRPTP-TIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSR 100
Query: 233 HDAGIYTCEAVNSQGAAVA-NISVSVH-YPAGIKSVSQNVVANPNEDAVLSC-TAIGNPL 289
D G+Y C A N G AV+ N S+ V + +V+ E AV+ C G+P
Sbjct: 101 PDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVVVGEPAVMECQPPRGHP- 159
Query: 290 LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM 349
I W++ G +D K + L+I + + G + CV N +G +
Sbjct: 160 -EPTISWKKDGSPLDDKDERITIRG--GKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 216
Query: 350 LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
L V +P P+ A V C+ + P P+ W K+ +LP ++Y
Sbjct: 217 LTVLERPSFVKRPS--NLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP---KSRYEI- 270
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLDVTSAPDQVV 462
++DH L I V D GSY C A N +G ++ T+ + V S P V
Sbjct: 271 --RDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV 318
Score = 72.1 bits (169), Expect = 7e-12
Identities = 96/375 (25%), Positives = 141/375 (37%), Gaps = 45/375 (12%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P T W KD + +S Y +D L + K+T D G YTC A N G A A+
Sbjct: 250 PVPTVRWRKDDGELPKSRYEIRDDHT------LKIRKVTAGDMGSYTCVAENMVGKAEAS 303
Query: 253 ISVSVHY---PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK------I 303
+++V P ++ V C A GNP A I W R+G +
Sbjct: 304 ATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPA--IFWRREGSQNLLFSYQ 361
Query: 304 DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS-ATKQ--DVMLIVKFKPEMDT 360
P+S + + T L I + ++G + C N GS TK +V ++ +P
Sbjct: 362 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVI 421
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
V V L C P P+ W K+GV V+T +
Sbjct: 422 RQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVL--VSTQDSRIKQLE-------NG 472
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDV-----------TSAPDQVVSL----T 465
VL I D G Y C A G +T + ++V + P+ + S
Sbjct: 473 VLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPE 532
Query: 466 VTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFT-VHGLEKNT 524
VT+V+ +TVTL W P + G I ++ V T + + GL+ N
Sbjct: 533 VTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNA 592
Query: 525 DYIFSVMAINKIGQS 539
Y+F V A N G S
Sbjct: 593 IYLFLVRAANAYGIS 607
Score = 46.4 bits (105), Expect = 4e-04
Identities = 54/215 (25%), Positives = 90/215 (41%), Gaps = 27/215 (12%)
Query: 259 YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-----DPKS--VTFE 311
+P I +++ + E A L+C A G P I+W + G ++ DP+S +
Sbjct: 27 FPPRIVEHPSDLIVSKGEPATLNCKAEGRP--TPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 312 PKNLTSYLIIRKAKSE-NLGNFQCVVNNGIGSATKQDVML-IVKFKPEMDTSPNFVKSAS 369
+L I+ KS + G + CV N +G A + L + + + +P+ V
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVV- 143
Query: 370 NVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT-SVLLINNV 427
VG+ + C+ + P P+ +W K+G L K++ IT L+I
Sbjct: 144 -VGEPAVMECQPPRGHPEPTISWKKDGSPLD-----------DKDERITIRGGKLMITYT 191
Query: 428 ATSDYGSYECGARNELGFSTTTV-KLDVTSAPDQV 461
SD G Y C N +G + V +L V P V
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFV 226
Score = 41.1 bits (92), Expect = 0.016
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P+ T+ W K+D ++ + + +I +T + Y C A N + T
Sbjct: 248 GDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVT--AGDMGSYTCVAENMVGKAEASAT 305
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+T+ V P V+ V+ G T C+ A+ NP + W R+G
Sbjct: 306 LTVQVGSEPPHFVVKPRDQVVALGRTVTFQCE-ATGNPQPAIFWRREG 352
Score = 32.7 bits (71), Expect = 5.5
Identities = 32/149 (21%), Positives = 58/149 (38%), Gaps = 13/149 (8%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKA-----VSA 78
P I + ++ G L C G P T+ W+K +++ T K ++ S
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNC-KAEGRPTPTIEWYKGGERVE-TDKDDPRSHRMLLPSG 86
Query: 79 EISILTNVTDNQAQ-----YRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPG 133
+ L V +++ Y C A N E + +L V + + ++ G
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEA-VSHNASLEVAILRDDFRQNPSDVMVVVG 145
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQN 162
A + C +P T+SW +DG P+ +
Sbjct: 146 EPAVMECQPPRGHPEPTISWKKDGSPLDD 174
Score = 32.3 bits (70), Expect = 7.3
Identities = 22/90 (24%), Positives = 35/90 (38%), Gaps = 4/90 (4%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D P V+ S++ G+ L CK + P P+ W K G ++ +
Sbjct: 26 DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++ + D G Y C ARN LG
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLG 115
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 89.4 bits (212), Expect = 5e-17
Identities = 77/280 (27%), Positives = 123/280 (43%), Gaps = 22/280 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
EP ++ + P T +W KDG P+ ++RI G L +T + DAG Y
Sbjct: 185 EPAVMECQPPRGHPEPTISWKKDGSPLDDK-----DERITIRGGKLMITYTRKSDAGKYV 239
Query: 240 CEAVNSQG---AAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
C N G + VA ++V + P+ +K S N+ ++ A C A G+P+ ++W
Sbjct: 240 CVGTNMVGERESEVAELTV-LERPSFVKRPS-NLAVTVDDSAEFKCEARGDPVPT--VRW 295
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ ++ PKS +E ++ L IRK + ++G++ CV N +G A + L V+ P
Sbjct: 296 RKDDGEL-PKS-RYEIRD-DHTLKIRKVTAGDMGSYTCVAENMVGKA-EASATLTVQEPP 351
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFA-EFHKNDH 415
P A +G+ C+ P P+ W + G + N Y +
Sbjct: 352 HFVVKPRDQVVA--LGRTVTFQCEATGNPQPAIFWRREGSQ---NLLFSYQPPQSSSRFS 406
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVT 455
++ T L I NV SD G Y C N G T L+VT
Sbjct: 407 VSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT 446
Score = 81.0 bits (191), Expect = 2e-14
Identities = 76/293 (25%), Positives = 122/293 (41%), Gaps = 26/293 (8%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSGNDRIISEGSMLNMT----KLTR 232
+ EP ++ +A+G P T W K G + T + ++ GS+ + + +R
Sbjct: 81 KGEPATLNCKAEGRPTP-TIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSR 139
Query: 233 HDAGIYTCEAVNSQGAAVA-NISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAI-GNPL 289
D G+Y C A N G AV+ N S+ V + +V+ E AV+ C G+P
Sbjct: 140 PDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP- 198
Query: 290 LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM 349
I W++ G +D K + L+I + + G + CV N +G +
Sbjct: 199 -EPTISWKKDGSPLDDKDERITIRG--GKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 255
Query: 350 LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
L V +P P+ + A V C+ + P P+ W K+ +LP ++Y
Sbjct: 256 LTVLERPSFVKRPSNL--AVTVDDSAEFKCEARGDPVPTVRWRKDDGELP---KSRYEI- 309
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++DH L I V D GSY C A N +G + + L V P VV
Sbjct: 310 --RDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVV 355
Score = 77.8 bits (183), Expect = 1e-13
Identities = 96/372 (25%), Positives = 141/372 (37%), Gaps = 42/372 (11%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P T W KD + +S Y +D L + K+T D G YTC A N G A A+
Sbjct: 289 PVPTVRWRKDDGELPKSRYEIRDDHT------LKIRKVTAGDMGSYTCVAENMVGKAEAS 342
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK------IDPK 306
+++V P ++ V C A GNP A I W R+G + P+
Sbjct: 343 ATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPA--IFWRREGSQNLLFSYQPPQ 400
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS-ATKQ--DVMLIVKFKPEMDTSPN 363
S + + T L I + ++G + C N GS TK +V ++ +P
Sbjct: 401 SSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG 460
Query: 364 FVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL 423
V V L C P P+ W K+GV V+T + VL
Sbjct: 461 PVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVL--VSTQDSRIKQLE-------NGVLQ 511
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDV-----------TSAPDQVVSL----TVTN 468
I D G Y C A G +T + ++V + P+ + S VT+
Sbjct: 512 IRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTD 571
Query: 469 VTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFT-VHGLEKNTDYI 527
V+ +TVTL W P + G I ++ V T + + GL+ N Y+
Sbjct: 572 VSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYL 631
Query: 528 FSVMAINKIGQS 539
F V A N G S
Sbjct: 632 FLVRAANAYGIS 643
Score = 48.0 bits (109), Expect = 1e-04
Identities = 55/215 (25%), Positives = 91/215 (42%), Gaps = 27/215 (12%)
Query: 259 YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-----DPKS--VTFE 311
+P I +++ + E A L+C A G P I+W + G ++ DP+S +
Sbjct: 66 FPPRIVEHPSDLIVSKGEPATLNCKAEGRP--TPTIEWYKGGERVETDKDDPRSHRMLLP 123
Query: 312 PKNLTSYLIIRKAKSE-NLGNFQCVVNNGIGSATKQDVML-IVKFKPEMDTSPNFVKSAS 369
+L I+ KS + G + CV N +G A + L + + + +P+ V A
Sbjct: 124 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVA- 182
Query: 370 NVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT-SVLLINNV 427
VG+ + C+ + P P+ +W K+G L K++ IT L+I
Sbjct: 183 -VGEPAVMECQPPRGHPEPTISWKKDGSPLD-----------DKDERITIRGGKLMITYT 230
Query: 428 ATSDYGSYECGARNELGFSTTTV-KLDVTSAPDQV 461
SD G Y C N +G + V +L V P V
Sbjct: 231 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFV 265
Score = 33.1 bits (72), Expect = 4.2
Identities = 32/149 (21%), Positives = 58/149 (38%), Gaps = 13/149 (8%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKA-----VSA 78
P I + ++ G L C G P T+ W+K +++ T K ++ S
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNC-KAEGRPTPTIEWYKGGERVE-TDKDDPRSHRMLLPSG 125
Query: 79 EISILTNVTDNQAQ-----YRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPG 133
+ L V +++ Y C A N E + +L V + + ++ G
Sbjct: 126 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEA-VSHNASLEVAILRDDFRQNPSDVMVAVG 184
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQN 162
A + C +P T+SW +DG P+ +
Sbjct: 185 EPAVMECQPPRGHPEPTISWKKDGSPLDD 213
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 89.0 bits (211), Expect = 6e-17
Identities = 81/284 (28%), Positives = 128/284 (45%), Gaps = 27/284 (9%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
EP ++ + P T +W KDG P+ ++RI G L +T + DAG Y
Sbjct: 146 EPAVMECQPPRGHPEPTISWKKDGSPLDDK-----DERITIRGGKLMITYTRKSDAGKYV 200
Query: 240 CEAVNSQG---AAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
C N G + VA ++V + P+ +K S N+ ++ A C A G+P+ ++W
Sbjct: 201 CVGTNMVGERESEVAELTV-LERPSFVKRPS-NLAVTVDDSAEFKCEARGDPVPT--VRW 256
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ ++ PKS +E ++ L IRK + ++G++ CV N +G A + L V+
Sbjct: 257 RKDDGEL-PKS-RYEIRD-DHTLKIRKVTAGDMGSYTCVAENMVGKA-EASATLTVQVGS 312
Query: 357 EMDTSPNFV-KSASNVGQVGRLM---CKCKSVPAPSFTWSKNGVKLPVNTSTKYFA-EFH 411
E P+FV K V +GR + C+ P P+ W + G + N Y +
Sbjct: 313 E---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ---NLLFSYQPPQSS 366
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVT 455
++ T L I NV SD G Y C N G T L+VT
Sbjct: 367 SRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT 410
Score = 78.2 bits (184), Expect = 1e-13
Identities = 76/295 (25%), Positives = 123/295 (41%), Gaps = 28/295 (9%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSGNDRIISEGSMLNMT----KLTR 232
+ EP ++ +A+G P T W K G + T + ++ GS+ + + +R
Sbjct: 42 KGEPATLNCKAEGRPTP-TIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSR 100
Query: 233 HDAGIYTCEAVNSQGAAVA-NISVSVH-YPAGIKSVSQNVVANPNEDAVLSC-TAIGNPL 289
D G+Y C A N G AV+ N S+ V + +V+ E AV+ C G+P
Sbjct: 101 PDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP- 159
Query: 290 LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM 349
I W++ G +D K + L+I + + G + CV N +G +
Sbjct: 160 -EPTISWKKDGSPLDDKDERITIRG--GKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 216
Query: 350 LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
L V +P P+ A V C+ + P P+ W K+ +LP ++Y
Sbjct: 217 LTVLERPSFVKRPS--NLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP---KSRYEI- 270
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLDVTSAPDQVV 462
++DH L I V D GSY C A N +G ++ T+ + V S P V
Sbjct: 271 --RDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV 318
Score = 72.1 bits (169), Expect = 7e-12
Identities = 96/375 (25%), Positives = 141/375 (37%), Gaps = 45/375 (12%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P T W KD + +S Y +D L + K+T D G YTC A N G A A+
Sbjct: 250 PVPTVRWRKDDGELPKSRYEIRDDHT------LKIRKVTAGDMGSYTCVAENMVGKAEAS 303
Query: 253 ISVSVHY---PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK------I 303
+++V P ++ V C A GNP A I W R+G +
Sbjct: 304 ATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPA--IFWRREGSQNLLFSYQ 361
Query: 304 DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS-ATKQ--DVMLIVKFKPEMDT 360
P+S + + T L I + ++G + C N GS TK +V ++ +P
Sbjct: 362 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVI 421
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
V V L C P P+ W K+GV V+T +
Sbjct: 422 RQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVL--VSTQDSRIKQLE-------NG 472
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDV-----------TSAPDQVVSL----T 465
VL I D G Y C A G +T + ++V + P+ + S
Sbjct: 473 VLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPE 532
Query: 466 VTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFT-VHGLEKNT 524
VT+V+ +TVTL W P + G I ++ V T + + GL+ N
Sbjct: 533 VTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNA 592
Query: 525 DYIFSVMAINKIGQS 539
Y+F V A N G S
Sbjct: 593 IYLFLVRAANAYGIS 607
Score = 48.0 bits (109), Expect = 1e-04
Identities = 55/215 (25%), Positives = 91/215 (42%), Gaps = 27/215 (12%)
Query: 259 YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-----DPKS--VTFE 311
+P I +++ + E A L+C A G P I+W + G ++ DP+S +
Sbjct: 27 FPPRIVEHPSDLIVSKGEPATLNCKAEGRP--TPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 312 PKNLTSYLIIRKAKSE-NLGNFQCVVNNGIGSATKQDVML-IVKFKPEMDTSPNFVKSAS 369
+L I+ KS + G + CV N +G A + L + + + +P+ V A
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVA- 143
Query: 370 NVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT-SVLLINNV 427
VG+ + C+ + P P+ +W K+G L K++ IT L+I
Sbjct: 144 -VGEPAVMECQPPRGHPEPTISWKKDGSPLD-----------DKDERITIRGGKLMITYT 191
Query: 428 ATSDYGSYECGARNELGFSTTTV-KLDVTSAPDQV 461
SD G Y C N +G + V +L V P V
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFV 226
Score = 41.1 bits (92), Expect = 0.016
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P+ T+ W K+D ++ + + +I +T + Y C A N + T
Sbjct: 248 GDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVT--AGDMGSYTCVAENMVGKAEASAT 305
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+T+ V P V+ V+ G T C+ A+ NP + W R+G
Sbjct: 306 LTVQVGSEPPHFVVKPRDQVVALGRTVTFQCE-ATGNPQPAIFWRREG 352
Score = 33.1 bits (72), Expect = 4.2
Identities = 32/149 (21%), Positives = 58/149 (38%), Gaps = 13/149 (8%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKA-----VSA 78
P I + ++ G L C G P T+ W+K +++ T K ++ S
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNC-KAEGRPTPTIEWYKGGERVE-TDKDDPRSHRMLLPSG 86
Query: 79 EISILTNVTDNQAQ-----YRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPG 133
+ L V +++ Y C A N E + +L V + + ++ G
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEA-VSHNASLEVAILRDDFRQNPSDVMVAVG 145
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQN 162
A + C +P T+SW +DG P+ +
Sbjct: 146 EPAVMECQPPRGHPEPTISWKKDGSPLDD 174
Score = 32.3 bits (70), Expect = 7.3
Identities = 22/90 (24%), Positives = 35/90 (38%), Gaps = 4/90 (4%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D P V+ S++ G+ L CK + P P+ W K G ++ +
Sbjct: 26 DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++ + D G Y C ARN LG
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLG 115
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 89.0 bits (211), Expect = 6e-17
Identities = 81/284 (28%), Positives = 128/284 (45%), Gaps = 27/284 (9%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
EP ++ + P T +W KDG P+ ++RI G L +T + DAG Y
Sbjct: 146 EPAVMECQPPRGHPEPTISWKKDGSPLDDK-----DERITIRGGKLMITYTRKSDAGKYV 200
Query: 240 CEAVNSQG---AAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
C N G + VA ++V + P+ +K S N+ ++ A C A G+P+ ++W
Sbjct: 201 CVGTNMVGERESEVAELTV-LERPSFVKRPS-NLAVTVDDSAEFKCEARGDPVPT--VRW 256
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ ++ PKS +E ++ L IRK + ++G++ CV N +G A + L V+
Sbjct: 257 RKDDGEL-PKS-RYEIRD-DHTLKIRKVTAGDMGSYTCVAENMVGKA-EASATLTVQVGS 312
Query: 357 EMDTSPNFV-KSASNVGQVGRLM---CKCKSVPAPSFTWSKNGVKLPVNTSTKYFA-EFH 411
E P+FV K V +GR + C+ P P+ W + G + N Y +
Sbjct: 313 E---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ---NLLFSYQPPQSS 366
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVT 455
++ T L I NV SD G Y C N G T L+VT
Sbjct: 367 SRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT 410
Score = 78.2 bits (184), Expect = 1e-13
Identities = 76/295 (25%), Positives = 123/295 (41%), Gaps = 28/295 (9%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSGNDRIISEGSMLNMT----KLTR 232
+ EP ++ +A+G P T W K G + T + ++ GS+ + + +R
Sbjct: 42 KGEPATLNCKAEGRPTP-TIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSR 100
Query: 233 HDAGIYTCEAVNSQGAAVA-NISVSVH-YPAGIKSVSQNVVANPNEDAVLSC-TAIGNPL 289
D G+Y C A N G AV+ N S+ V + +V+ E AV+ C G+P
Sbjct: 101 PDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP- 159
Query: 290 LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM 349
I W++ G +D K + L+I + + G + CV N +G +
Sbjct: 160 -EPTISWKKDGSPLDDKDERITIRG--GKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 216
Query: 350 LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
L V +P P+ A V C+ + P P+ W K+ +LP ++Y
Sbjct: 217 LTVLERPSFVKRPS--NLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP---KSRYEI- 270
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLDVTSAPDQVV 462
++DH L I V D GSY C A N +G ++ T+ + V S P V
Sbjct: 271 --RDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV 318
Score = 72.1 bits (169), Expect = 7e-12
Identities = 96/375 (25%), Positives = 141/375 (37%), Gaps = 45/375 (12%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P T W KD + +S Y +D L + K+T D G YTC A N G A A+
Sbjct: 250 PVPTVRWRKDDGELPKSRYEIRDDHT------LKIRKVTAGDMGSYTCVAENMVGKAEAS 303
Query: 253 ISVSVHY---PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK------I 303
+++V P ++ V C A GNP A I W R+G +
Sbjct: 304 ATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPA--IFWRREGSQNLLFSYQ 361
Query: 304 DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS-ATKQ--DVMLIVKFKPEMDT 360
P+S + + T L I + ++G + C N GS TK +V ++ +P
Sbjct: 362 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVI 421
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
V V L C P P+ W K+GV V+T +
Sbjct: 422 RQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVL--VSTQDSRIKQLE-------NG 472
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDV-----------TSAPDQVVSL----T 465
VL I D G Y C A G +T + ++V + P+ + S
Sbjct: 473 VLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPE 532
Query: 466 VTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFT-VHGLEKNT 524
VT+V+ +TVTL W P + G I ++ V T + + GL+ N
Sbjct: 533 VTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNA 592
Query: 525 DYIFSVMAINKIGQS 539
Y+F V A N G S
Sbjct: 593 IYLFLVRAANAYGIS 607
Score = 48.0 bits (109), Expect = 1e-04
Identities = 55/215 (25%), Positives = 91/215 (42%), Gaps = 27/215 (12%)
Query: 259 YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-----DPKS--VTFE 311
+P I +++ + E A L+C A G P I+W + G ++ DP+S +
Sbjct: 27 FPPRIVEHPSDLIVSKGEPATLNCKAEGRP--TPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 312 PKNLTSYLIIRKAKSE-NLGNFQCVVNNGIGSATKQDVML-IVKFKPEMDTSPNFVKSAS 369
+L I+ KS + G + CV N +G A + L + + + +P+ V A
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVA- 143
Query: 370 NVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT-SVLLINNV 427
VG+ + C+ + P P+ +W K+G L K++ IT L+I
Sbjct: 144 -VGEPAVMECQPPRGHPEPTISWKKDGSPLD-----------DKDERITIRGGKLMITYT 191
Query: 428 ATSDYGSYECGARNELGFSTTTV-KLDVTSAPDQV 461
SD G Y C N +G + V +L V P V
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFV 226
Score = 41.1 bits (92), Expect = 0.016
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P+ T+ W K+D ++ + + +I +T + Y C A N + T
Sbjct: 248 GDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVT--AGDMGSYTCVAENMVGKAEASAT 305
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
+T+ V P V+ V+ G T C+ A+ NP + W R+G
Sbjct: 306 LTVQVGSEPPHFVVKPRDQVVALGRTVTFQCE-ATGNPQPAIFWRREG 352
Score = 33.1 bits (72), Expect = 4.2
Identities = 32/149 (21%), Positives = 58/149 (38%), Gaps = 13/149 (8%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKA-----VSA 78
P I + ++ G L C G P T+ W+K +++ T K ++ S
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNC-KAEGRPTPTIEWYKGGERVE-TDKDDPRSHRMLLPSG 86
Query: 79 EISILTNVTDNQAQ-----YRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPG 133
+ L V +++ Y C A N E + +L V + + ++ G
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEA-VSHNASLEVAILRDDFRQNPSDVMVAVG 145
Query: 134 IEATLICDSASSNPPATLSWWRDGIPVQN 162
A + C +P T+SW +DG P+ +
Sbjct: 146 EPAVMECQPPRGHPEPTISWKKDGSPLDD 174
Score = 32.3 bits (70), Expect = 7.3
Identities = 22/90 (24%), Positives = 35/90 (38%), Gaps = 4/90 (4%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D P V+ S++ G+ L CK + P P+ W K G ++ +
Sbjct: 26 DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++ + D G Y C ARN LG
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLG 115
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 88.6 bits (210), Expect = 8e-17
Identities = 93/378 (24%), Positives = 156/378 (41%), Gaps = 37/378 (9%)
Query: 175 VGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRH 233
+G+ +A G+P TW K G + + + + S G++L + L T
Sbjct: 43 IGVSGGVASFVCQATGDPKP-RVTWNKKGKKVNSQRFET-IEFDESAGAVLRIQPLRTPR 100
Query: 234 DAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIG 286
D +Y C A NS G + ++V P+G ++ Q V A + C A G
Sbjct: 101 DENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASG 160
Query: 287 NPLLAEHIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATK 345
NP I W + +DP + K L S L I ++ + G ++CV N G
Sbjct: 161 NP--DPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 346 QDVMLIVKFKPEMDTSPNF--VKSASNVGQVGRLMCKCKSV--PAPSFTWSKNGVKLPVN 401
L V+ + +P F + + + G + C +V P P W + L
Sbjct: 219 SPANLYVRVRR---VAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTP- 274
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
++D +VL + +V D +Y C A + LG ++ V S P
Sbjct: 275 ----------EDDMPVGRNVLELTDV--KDSANYTCVAMSSLGVIEAVAQITVKSLPKAP 322
Query: 462 VSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYR-KVFDDSYKYEDVLPKHATNFTVHGL 520
+ VT T +++T+ W G + S+Y I Y+ K D Y+ ++ + T +++ GL
Sbjct: 323 GTPMVTENTATSITITWDSGNPDPV-SYYVIEYKSKSQDGPYQIKEDIT--TTRYSIGGL 379
Query: 521 EKNTDYIFSVMAINKIGQ 538
N++Y V A+N IGQ
Sbjct: 380 SPNSEYEIWVSAVNSIGQ 397
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 10/132 (7%)
Query: 37 AGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSAEISILTNVTDNQAQ- 92
+G V C +TG +P +TW K KK++S T D++ A + I T
Sbjct: 46 SGGVASFVCQATG-DPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENV 104
Query: 93 YRCEATNSATEIPLFETVT-LNVHFAPEA---VKVRAEPDVLKPGIEATLICDSASSNPP 148
Y C A NS EI + +T L P + + + V++ AT++C +AS NP
Sbjct: 105 YECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLC-AASGNPD 163
Query: 149 ATLSWWRDGIPV 160
++W++D +PV
Sbjct: 164 PEITWFKDFLPV 175
Score = 32.3 bits (70), Expect = 7.3
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 47 STGGNPLATLTWFKNDKKIHSTTKT--TDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+ GNP +TWFK+ + + + S + I ++ +Q +Y C ATNSA
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSA 213
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 88.6 bits (210), Expect = 8e-17
Identities = 93/378 (24%), Positives = 156/378 (41%), Gaps = 37/378 (9%)
Query: 175 VGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRH 233
+G+ +A G+P TW K G + + + + S G++L + L T
Sbjct: 69 IGVSGGVASFVCQATGDPKP-RVTWNKKGKKVNSQRFET-IEFDESAGAVLRIQPLRTPR 126
Query: 234 DAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIG 286
D +Y C A NS G + ++V P+G ++ Q V A + C A G
Sbjct: 127 DENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASG 186
Query: 287 NPLLAEHIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATK 345
NP I W + +DP + K L S L I ++ + G ++CV N G
Sbjct: 187 NP--DPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 244
Query: 346 QDVMLIVKFKPEMDTSPNF--VKSASNVGQVGRLMCKCKSV--PAPSFTWSKNGVKLPVN 401
L V+ + +P F + + + G + C +V P P W + L
Sbjct: 245 SPANLYVRVRR---VAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTP- 300
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
++D +VL + +V D +Y C A + LG ++ V S P
Sbjct: 301 ----------EDDMPVGRNVLELTDV--KDSANYTCVAMSSLGVIEAVAQITVKSLPKAP 348
Query: 462 VSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYR-KVFDDSYKYEDVLPKHATNFTVHGL 520
+ VT T +++T+ W G + S+Y I Y+ K D Y+ ++ + T +++ GL
Sbjct: 349 GTPMVTENTATSITITWDSGNPDPV-SYYVIEYKSKSQDGPYQIKEDIT--TTRYSIGGL 405
Query: 521 EKNTDYIFSVMAINKIGQ 538
N++Y V A+N IGQ
Sbjct: 406 SPNSEYEIWVSAVNSIGQ 423
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 10/132 (7%)
Query: 37 AGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSAEISILTNVTDNQAQ- 92
+G V C +TG +P +TW K KK++S T D++ A + I T
Sbjct: 72 SGGVASFVCQATG-DPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENV 130
Query: 93 YRCEATNSATEIPLFETVT-LNVHFAPEA---VKVRAEPDVLKPGIEATLICDSASSNPP 148
Y C A NS EI + +T L P + + + V++ AT++C +AS NP
Sbjct: 131 YECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLC-AASGNPD 189
Query: 149 ATLSWWRDGIPV 160
++W++D +PV
Sbjct: 190 PEITWFKDFLPV 201
Score = 32.3 bits (70), Expect = 7.3
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 47 STGGNPLATLTWFKNDKKIHSTTKT--TDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+ GNP +TWFK+ + + + S + I ++ +Q +Y C ATNSA
Sbjct: 183 AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSA 239
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 87.8 bits (208), Expect = 1e-16
Identities = 77/291 (26%), Positives = 127/291 (43%), Gaps = 26/291 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P I W KDG ++ S +D +L ++ LT D G+Y+C+A N GA +
Sbjct: 4505 PVIETIWQKDGAALSPSPNWKISDA--ENKHILELSNLTIQDRGVYSCKASNKFGADICQ 4562
Query: 253 IS-VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS---V 308
+ + P IK + + V + N+ L C + + + W + G K+ P +
Sbjct: 4563 AELIIIDKPHFIKEL-EPVQSAINKKVHLECQVDEDRKVT--VTWSKDGQKLPPGKDYKI 4619
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DTSPNFVK 366
FE K T L I AK ++ G + C +N GS++ + V+ P P+++
Sbjct: 4620 CFEDKIAT--LEIPLAKLKDSGTYVCTASNEAGSSSCS-ATVTVREPPSFVKKVDPSYLM 4676
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV-NTSTKYFAEFHKNDHITYTSVLLIN 425
G+ RL CK K P TW KN +L NT YF + ++L I
Sbjct: 4677 LP---GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF--------VNSEAILDIT 4725
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTL 476
+V D GSY C A N++G + + ++ + P + +L ++ T L
Sbjct: 4726 DVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNAL 4776
Score = 87.8 bits (208), Expect = 1e-16
Identities = 75/275 (27%), Positives = 118/275 (42%), Gaps = 20/275 (7%)
Query: 198 TWTKDGLPITQSSYSSGNDRIISEGSM--LNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
TW+KD I GN I G+ L + K+ + D+G YTC+A N G + + +
Sbjct: 7230 TWSKDNKEIRPG----GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 7285
Query: 256 SVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPK 313
SV P +K + + VA E L C G+P + + W R ++ +
Sbjct: 7286 SVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEI--KVSWFRNDSELHESWKYNMSFI 7343
Query: 314 NLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQ 373
N + L I +A +E+ G++ C +NG+G A+ L VK P P+ V +
Sbjct: 7344 NSVALLTINEASAEDSGDYICEAHNGVGDAS-CSTALTVKAPPVFTQKPSPVGALKGSDV 7402
Query: 374 VGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYG 433
+ L C+ P W K+ + V S K+ K + + L I N+ SD G
Sbjct: 7403 I--LQCEISGTPPFEVVWVKD--RKQVRNSKKF-----KITSKHFDTSLHILNLEASDVG 7453
Query: 434 SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
Y C A NE+G T + + P V L+ T+
Sbjct: 7454 EYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTS 7488
Score = 81.0 bits (191), Expect = 2e-14
Identities = 67/273 (24%), Positives = 113/273 (41%), Gaps = 13/273 (4%)
Query: 181 PLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTC 240
P+++ G PP I+ +W KD I+QS S + + ++L + + T D Y+C
Sbjct: 7870 PIVLEATYTGTPP-ISVSWIKDEYLISQSERCSIT--MTEKSTILEILESTIEDYAQYSC 7926
Query: 241 EAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
N G + VSV P ++V A E A L C G P + I W ++
Sbjct: 7927 LIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEI--RISWYKEH 7984
Query: 301 YKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
K+ + + KN + L+I K ++G + C +N +G+ V++I + K
Sbjct: 7985 TKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPF 8044
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+ +G C+ +W K+GV L + + + F N
Sbjct: 8045 FARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQ--TSFVHN-----V 8097
Query: 420 SVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
+ L I S G Y C A N LG ++++ KL
Sbjct: 8098 ATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130
Score = 81.0 bits (191), Expect = 2e-14
Identities = 81/324 (25%), Positives = 135/324 (41%), Gaps = 30/324 (9%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G P I W KD I +SS + + ++L M L+ D+G YTCEA N+ G+A
Sbjct: 8257 GGSPEIKVLWYKDETEIQESSKFRMS--FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSA 8314
Query: 250 VANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSV 308
++ S+ V P + + D L C G P H+ W + ++ K
Sbjct: 8315 SSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPF--HVSWYKDKRELRSGKKY 8372
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSA 368
+N + + I + ++G +QC N +GS T + + P FVK
Sbjct: 8373 KIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSI-------ALKAPPRFVKKL 8425
Query: 369 SN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLI 424
S+ VG+ +L + S W K+ ++ V S + + +N + L
Sbjct: 8426 SDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEI-VRESDNIWISYSEN-----IATLQF 8479
Query: 425 NNVATSDYGSYECGARNELG----FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLE-WV 479
+ V ++ G Y C +N+ G F+T +V L+ + ++ S+ VT T T TLE V
Sbjct: 8480 SRVEPANAGKYTCQIKNDAGMQECFATLSV-LEPATIVEKPESIKVT--TGDTCTLECTV 8536
Query: 480 PGFDGGLQSWYRIRYRKVFDDSYK 503
G W++ D+ YK
Sbjct: 8537 AGTPELSTKWFKDGKELTSDNKYK 8560
Score = 78.6 bits (185), Expect = 9e-14
Identities = 71/277 (25%), Positives = 113/277 (40%), Gaps = 23/277 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
+I+ G P I+ TW KDG IT S N + +L + T+ DAG Y+CE
Sbjct: 6930 IILESTYTGTLP-ISVTWKKDGFNITTSEKC--NIVTTEKTCILEILNSTKRDAGQYSCE 6986
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGY 301
N G V VS P + + + A + L C G P + + W +
Sbjct: 6987 IENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEIT--VSWYKGDT 7044
Query: 302 KI--DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
K+ P+ T+ N+ + L+ K + G + C N IG+A+ + V I E
Sbjct: 7045 KLRPTPEYRTYFTNNVAT-LVFNKVNINDSGEYTCKAENSIGTASSKTVFRI----QERQ 7099
Query: 360 TSPNFVKSASNVGQ-VG---RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P+F + ++ Q VG L C+ W ++GV L + E +
Sbjct: 7100 LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDD-------ENLQTSF 7152
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
+ + L I S G Y C A N LG ++++ +L
Sbjct: 7153 VDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 7189
Score = 78.6 bits (185), Expect = 9e-14
Identities = 82/373 (21%), Positives = 144/373 (38%), Gaps = 21/373 (5%)
Query: 173 NTVGIEN-EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT 231
N IE +PLI+ G PP I+ TW K+G+ +T S N + ++L + T
Sbjct: 8802 NDYSIEKGKPLILEGTFTGTPP-ISVTWKKNGINVTPSQRC--NITTTEKSAILEIPSST 8858
Query: 232 RHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA 291
DAG Y C N+ G + + + P + V + + A L C G P +
Sbjct: 8859 VEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIG 8918
Query: 292 EHIKWERKGYKIDPKSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
+ W + K+ P + +N + L+ + + G + C N +G + +
Sbjct: 8919 --VSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT 8976
Query: 351 IVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
+ + K S VG C S +W K+G P+ S F
Sbjct: 8977 VQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDG--KPLKDSPNVQTSF 9034
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD----QVVSLTV 466
N T+ L I S G Y C A N +G ++++ +L +T + + V
Sbjct: 9035 LDN-----TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPV 9089
Query: 467 TNVTHSTVTLE-WVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTD 525
V + E V G SW + + KY+ +++ + TV ++K
Sbjct: 9090 DAVVGESADFECHVTGTQPIKVSW--AKDSREIRSGGKYQISYLENSAHLTVLKVDKGDS 9147
Query: 526 YIFSVMAINKIGQ 538
++ A+N++G+
Sbjct: 9148 GQYTCYAVNEVGK 9160
Score = 78.6 bits (185), Expect = 9e-14
Identities = 82/308 (26%), Positives = 126/308 (40%), Gaps = 28/308 (9%)
Query: 161 QNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI-- 218
+N P FD + + E G P I +W KD I S G +I
Sbjct: 9077 KNPPFFDIRLA-PVDAVVGESADFECHVTGTQP-IKVSWAKDSREIR----SGGKYQISY 9130
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQG----AAVANISVSVHYPAGIKSVSQNVVANP 274
+ + L + K+ + D+G YTC AVN G A NI + P+ K +S+ V
Sbjct: 9131 LENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETE 9190
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS---VTFEPKNLTSYLIIRKAKSENLGN 331
L G+ + + W + +I P S +TF KN T L +RKA + G
Sbjct: 9191 GNSFKLEGRVAGSQPIT--VAWYKNNIEIQPTSNCEITF--KNNTLVLQVRKAGMNDAGL 9246
Query: 332 FQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW 391
+ C V+N GSA ++I + K + + G+ +L C + W
Sbjct: 9247 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQW 9306
Query: 392 SKNGVKL-PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
K G ++ P + + FA + T+VL + +VA +D G Y C A N G TT
Sbjct: 9307 LKAGREIKPSDRCSFSFA--------SGTAVLELRDVAKADSGDYVCKASNVAGSDTTKS 9358
Query: 451 KLDVTSAP 458
K+ + P
Sbjct: 9359 KVTIKDKP 9366
Score = 75.8 bits (178), Expect = 6e-13
Identities = 75/273 (27%), Positives = 118/273 (43%), Gaps = 19/273 (6%)
Query: 193 PSITYTWTKDGLPITQSSYSS-GNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG--AA 249
P++ + W K G I +S S + + IS +L T++ D G YTC+A N G +
Sbjct: 4410 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR-TQVV--DCGEYTCKASNEYGSVSC 4466
Query: 250 VANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK-SV 308
A ++V+ YP S +++ + A CT G P++ E I W++ G + P +
Sbjct: 4467 TATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVI-ETI-WQKDGAALSPSPNW 4524
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSA 368
L + ++ G + C +N G+ Q ++I+ KP V+SA
Sbjct: 4525 KISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIID-KPHFIKELEPVQSA 4583
Query: 369 SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVA 428
N + L C+ + TWSK+G KLP K E D I + L I
Sbjct: 4584 IN--KKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFE----DKI---ATLEIPLAK 4634
Query: 429 TSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
D G+Y C A NE G S+ + + V P V
Sbjct: 4635 LKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 4667
Score = 75.8 bits (178), Expect = 6e-13
Identities = 76/300 (25%), Positives = 128/300 (42%), Gaps = 31/300 (10%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS--YSSGNDRIISEGSMLNMTKL 230
NT + G+PP I+ TW KD + + Y S D + + L + +
Sbjct: 5983 NTTTVLKSSATFQSTVAGSPP-ISITWLKDDQILDEDDNVYISFVDSVAT----LQIRSV 6037
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLL 290
+G YTC+A N G + V PA I +++V + L C G P L
Sbjct: 6038 DNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPEL 6097
Query: 291 AEHIKWERKGYKIDPK---SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQD 347
+KW + G +I P S++FE N+ S+ I+ ++ G + V N GS++
Sbjct: 6098 --KVKWLKDGKQIVPSRYFSMSFE-NNVASFR-IQSVMKQDSGQYTFKVENDFGSSSCDA 6153
Query: 348 VMLIVKFKPEMDTSPNFVKSASNVGQV--GRLMCKCK---SVPAPSFTWSKNGVKLPVNT 402
+ ++ + + P+F K + + +V + +CK S+P S W K+G + ++T
Sbjct: 6154 YLRVL----DQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPI-SAQWFKDGKE--IST 6206
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
S KY H+ + L +NN+ D +Y C N G + L V P +V
Sbjct: 6207 SAKYRLVCHER-----SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLV 6261
Score = 74.9 bits (176), Expect = 1e-12
Identities = 74/290 (25%), Positives = 122/290 (42%), Gaps = 16/290 (5%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G+ P I+ W KD I+ S + + L +++L D+G YTC A N G
Sbjct: 5627 GSHP-ISIQWFKDDQEISASEKYKFSFH--DNTAFLEISQLEGTDSGTYTCSATNKAGHN 5683
Query: 250 VANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVT 309
+ ++V P Q+ NPN L G + IKW + ++ +
Sbjct: 5684 QCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMT--IKWFKDNKELHSGAAR 5741
Query: 310 FEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSA 368
K+ TS L + AK+ + G + C ++N +G+AT + L VK P+ P+ V
Sbjct: 5742 SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKPSPVLVL 5800
Query: 369 SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVA 428
N GQ C+ P +W +G ++ + H I + I+
Sbjct: 5801 RN-GQSTTFECQITGTPKIRVSWYLDGNEITA-------IQKHGISFIDGLATFQISGAR 5852
Query: 429 TSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL-TVTNVTHSTVTLE 477
+ G+Y C ARN+ G ++ +++L V P + L V V +S V LE
Sbjct: 5853 VENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELE 5902
Score = 72.9 bits (171), Expect = 4e-12
Identities = 95/392 (24%), Positives = 158/392 (40%), Gaps = 34/392 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V+ P F + + + E + + G+P I TW K+ +++S+ +
Sbjct: 4658 VTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPV-IQVTWFKNNKELSESN--TVRMY 4714
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG-IKSVSQ-NVVANPN 275
++ ++L++T + D+G Y+CEAVN G+ + + + P IK++ ++V N
Sbjct: 4715 FVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTN 4774
Query: 276 EDAVLSCTAIGNPLLAEHIKW--ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
A+L C G I W ++K + K F K+L L I S ++G ++
Sbjct: 4775 --ALLQCEVSGTGPF--EISWFKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYE 4829
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSF 389
CVV N +G L+ + P FVK ++ GQ L + S
Sbjct: 4830 CVVANEVGKCGCMATHLLKE-------PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISV 4882
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
TW K G ++ + K F +VL+I +V S G Y C A NE G T+
Sbjct: 4883 TWMK-GQEV-IREDGKIKMSFSNG-----VAVLIIPDVQISFGGKYTCLAENEAGSQTSV 4935
Query: 450 VKLDVTSAPDQVVSLTVTNVT-HSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV 507
+L V + + VT TLE+ V G WY+ V Y+
Sbjct: 4936 GELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFK 4995
Query: 508 LPKHATNFTVHGLEKNTDYIFSVMAINKIGQS 539
F L + Y F + N++G S
Sbjct: 4996 NNVAQLKFYSAELHDSGQYTFEIS--NEVGSS 5025
Score = 72.1 bits (169), Expect = 7e-12
Identities = 73/277 (26%), Positives = 115/277 (41%), Gaps = 23/277 (8%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSM-LNMTKLTRHDAGIYTCEAVNS 245
+ G+ P I+ W KDG I S S+ + E S+ L + L D YTC+ N
Sbjct: 6186 KVSGSLP-ISAQWFKDGKEI---STSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNV 6241
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G + ++V P A P+ G P IKW + ++
Sbjct: 6242 AGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFK--IKWFKDDVELVS 6299
Query: 306 KSVTFEP-KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV---KFKPEMDTS 361
F + TS+L + + G + C V N +GS + ++L+ KF +++ S
Sbjct: 6300 GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEAS 6359
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
VK+ G RL CK P W +N +LP S KY F I +V
Sbjct: 6360 -KIVKA----GDSSRLECKIAGSPEIRVVWFRNEHELP--ASDKYRMTF-----IDSVAV 6407
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ +NN++T D G + C A+N G ++ + K+ V P
Sbjct: 6408 IQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 6444
Score = 70.5 bits (165), Expect = 2e-11
Identities = 71/292 (24%), Positives = 123/292 (42%), Gaps = 20/292 (6%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G P I TW KD I + ++ + L + K+ + DAG YTC A N G
Sbjct: 8164 GTAP-IKITWAKDNREIRPGG--NYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKD 8220
Query: 250 VANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSV 308
+ + V P IK + + + +E C G+P + + W + +I +S
Sbjct: 8221 SCSAHLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEI--KVLWYKDETEIQ-ESS 8277
Query: 309 TFEPKNLTSYLII--RKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
F + S ++ E+ G++ C +N GSA+ L VK P P+ ++
Sbjct: 8278 KFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSAS-SSTSLKVKEPPIFRKKPHPIE 8336
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
+ G L C+ + P +W K+ K + + KY + + +T +L N
Sbjct: 8337 TLK--GADVHLECELQGTPPFHVSWYKD--KRELRSGKKY--KIMSENFLTSIHIL---N 8387
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLT-VTNVTHSTVTLE 477
V +D G Y+C A N++G T + + + P V L+ ++ V V L+
Sbjct: 8388 VDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQ 8439
Score = 68.5 bits (160), Expect = 9e-11
Identities = 43/161 (26%), Positives = 77/161 (47%), Gaps = 8/161 (4%)
Query: 382 KSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARN 441
++VP P+ +W K+G ++ + KNDHI+ + L + +D G Y N
Sbjct: 15338 RAVPVPTVSWHKDGKEVKASDRLTM-----KNDHIS--AHLEVPKSVRADAGIYTITLEN 15390
Query: 442 ELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDD 500
+LG +T ++ + V P + +++T S+ L W P FDGG + + R+
Sbjct: 15391 KLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR 15450
Query: 501 SYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ ++ ++TV L N +Y F V A+NK+G +Y
Sbjct: 15451 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 15491
Score = 68.1 bits (159), Expect = 1e-10
Identities = 71/284 (25%), Positives = 113/284 (39%), Gaps = 18/284 (6%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP F N + N + + G+ P + +W KDG I S +
Sbjct: 5039 APFFTKPLR-NVDSVVNGTCRLDCKIAGSLP-MRVSWFKDGKEIAASDRY--RIAFVEGT 5094
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
+ L + ++ +DAG +TC A NS G+ ++ ++ V P + + P L
Sbjct: 5095 ASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKS 5154
Query: 283 TAIGNPLLAEHIKWERKGYK--IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
T G+ L I+W KG K + S + L S L + K+ + G + C V+N +
Sbjct: 5155 TFQGSTPLT--IRWF-KGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSN-V 5210
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV 400
+ L VK +P G +L CK P TW N + +
Sbjct: 5211 AGGVECSANLFVK-EPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDRE--I 5267
Query: 401 NTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
S+K H+ + T+VL + +V D G Y C A+NE G
Sbjct: 5268 KESSK-----HRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 5306
Score = 67.7 bits (158), Expect = 2e-10
Identities = 85/390 (21%), Positives = 154/390 (39%), Gaps = 29/390 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V+ P F + V + E + + + G+P I +W ++ + +S N
Sbjct: 7285 LSVKEPPKFVKKLEASKVAKQGESIQLECKISGSP-EIKVSWFRNDSELHESW--KYNMS 7341
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
I+ ++L + + + D+G Y CEA N G A + +++V P V A D
Sbjct: 7342 FINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSD 7401
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
+L C G P + W + ++ + K K+ + L I ++ ++G + C
Sbjct: 7402 VILQCEISGTPPF--EVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKA 7459
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWS 392
N +GS T VKFK P FVK S+ +G L + S W
Sbjct: 7460 TNEVGSDT---CSCSVKFK----EPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWL 7512
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ ++ + S F N + L + + S+ G Y C +N+ G + L
Sbjct: 7513 KDRGEV-IRESENTRISFIDN-----IATLQLGSPEASNSGKYICQIKNDAGMRECSAVL 7566
Query: 453 DVTSAPDQVVSL--TVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLP 509
V P +++ +T T + LE V G W++ R++ DS K+
Sbjct: 7567 TVLE-PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFK-DGRELSADS-KHHITFI 7623
Query: 510 KHATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ + E + ++S N +G+S
Sbjct: 7624 NKVASLKIPCAEMSDKGLYSFEVKNSVGKS 7653
Score = 66.5 bits (155), Expect = 4e-10
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT-YTSVLLINNVATSDYGSY 435
++ K K VP P+ TW K K P N + + H N + T L+I SD G Y
Sbjct: 17063 IVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY-DTHVNKLVVDDTCTLVIPQSRRSDTGLY 17121
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRI 492
A N LG ++ ++L+V P V + +V+ +TL W P DGG + + Y I
Sbjct: 17122 TITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVI 17181
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ ++ + PK T +T+ L + +Y+F +MA NK G
Sbjct: 17182 EKREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMAQNKYG 17225
Score = 64.5 bits (150), Expect = 1e-09
Identities = 69/307 (22%), Positives = 117/307 (38%), Gaps = 17/307 (5%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ ++ P F + TV + EP + +G P I W K+ + + S +
Sbjct: 6531 VKLKEPPRFVSKLNSLTV-VAGEPAELQASIEGAQP-IFVQWLKEKEEVIRESENI-RIT 6587
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
+ + L K +AG Y C+ N G ++ V PA I + + E
Sbjct: 6588 FVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVGET 6647
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
L C G P L+ ++W + G + + F N S L I + ++ G + V
Sbjct: 6648 CTLECKVAGTPELS--VEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQV 6705
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMC--KCKSVPAPSFTWSKN 394
N +G ++ V+ + + P+F + N G V C +CK + + +
Sbjct: 6706 QNNVGKSSCTAVVDV----SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWF 6761
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
K + + KY F N L +N++ +SD G+Y C A N G L V
Sbjct: 6762 HEKTKIVSGAKYQTTFSDN-----VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV 6816
Query: 455 TSAPDQV 461
P V
Sbjct: 6817 QEPPSFV 6823
Score = 63.7 bits (148), Expect = 3e-09
Identities = 70/292 (23%), Positives = 112/292 (38%), Gaps = 25/292 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ VQ P F+ T V + L + G PP W K + S N
Sbjct: 7755 LTVQEPPSFEQTPDSVEV-LPGMSLTFTSVIRGTPP-FKVKWFKGSRELVPGE--SCNIS 7810
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
+ + L + ++ ++G Y+C N G+A + V PA +
Sbjct: 7811 LEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSP 7870
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPK---SVTFEPKNLTSYLIIRKAKSENLGNFQC 334
VL T G P ++ + W + Y I S+T K ++ L I ++ E+ + C
Sbjct: 7871 IVLEATYTGTPPIS--VSWIKDEYLISQSERCSITMTEK--STILEILESTIEDYAQYSC 7926
Query: 335 VVNNGIGSATKQDV--MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWS 392
++ N G QD+ L+ +P P + +G+ L CK P +W
Sbjct: 7927 LIENEAG----QDICEALVSVLEPPYFIEP-LEHVEAVIGEPATLQCKVDGTPEIRISWY 7981
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
K KL ++ Y +F N + L+IN V SD G Y C A N +G
Sbjct: 7982 KEHTKL--RSAPAYKMQFKNN-----VASLVINKVDHSDVGEYSCKADNSVG 8026
Score = 63.7 bits (148), Expect = 3e-09
Identities = 61/239 (25%), Positives = 101/239 (42%), Gaps = 18/239 (7%)
Query: 306 KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN--GIGS-ATKQDVMLIVK-FKPEMDTS 361
K T +T + ++ +++ NF+ N G+G A DV ++ + P+ +
Sbjct: 21648 KDTTGTALRITQF-VVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELD 21706
Query: 362 PNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
++ G R+ K PAP TW+K+ + L K A + T
Sbjct: 21707 AELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL------KNRANIENTESFT--- 21757
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-V 479
+L+I D G + N G + V + V P V++L T++T +VTL W +
Sbjct: 21758 LLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDL 21817
Query: 480 PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
P DGG + + Y + R+ SY H + V GL + +Y F VMA N+ G
Sbjct: 21818 PLIDGGSRITNYIVEKREATRKSYSTATT-KCHKCTYKVTGLSEGCEYFFRVMAENEYG 21875
Score = 61.7 bits (143), Expect = 1e-08
Identities = 67/319 (21%), Positives = 126/319 (39%), Gaps = 23/319 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V P F + + + EP + + DG P I +W K+ + S + +
Sbjct: 7941 VSVLEPPYFIEPLEH-VEAVIGEPATLQCKVDGTP-EIRISWYKEHTKLR--SAPAYKMQ 7996
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH---YPAGIKSVSQNVVANP 274
+ + L + K+ D G Y+C+A NS GA ++ + + P ++V
Sbjct: 7997 FKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARKLKDVHETL 8056
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGY--KIDPKSVTFEPKNLTSYLIIRKAKSENLGNF 332
C G+ L + W + G K D T N+ + I++ +S ++G +
Sbjct: 8057 GFPVAFECRINGSEPL--QVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQS-HIGQY 8113
Query: 333 QCVVNNGIGSATKQDVMLIVKFK--PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C +N +G+A+ +++ + + P D P V A +G+ G C T
Sbjct: 8114 NCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLA--LGESGTFKCHVTGTAPIKIT 8171
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W+K+ ++ + +K + T+ L + V D G Y C A N G + +
Sbjct: 8172 WAKDNREIRPGGN-------YKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSA 8224
Query: 451 KLDVTSAPDQVVSLTVTNV 469
L V P + L + +
Sbjct: 8225 HLGVQEPPRFIKKLEPSRI 8243
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/170 (27%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
VGQ R++ + K P P TW+K G L + + + L I +
Sbjct: 18849 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE-------LQIKEAVRA 18901
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFD-GGLQ-S 488
D+G Y A+N G + + ++V P +L VTNVT T+ W D GG + +
Sbjct: 18902 DHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEIT 18961
Query: 489 WYRIRYRKVFDDSYKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIG 537
+ + YRK + K ++ T + L N +Y F V A NK+G
Sbjct: 18962 NFIVEYRK---PNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG 19008
Score = 61.7 bits (143), Expect = 1e-08
Identities = 53/200 (26%), Positives = 83/200 (41%), Gaps = 17/200 (8%)
Query: 356 PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D NF ++ G RL + P P+ WSK L + A+ H D
Sbjct: 29282 PELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR------ADIHTTD 29335
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S L + N +D G Y N G + T + V P +T +VT +
Sbjct: 29336 SF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSA 29392
Query: 475 TLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATN--FTVHGLEKNTDYIFSVM 531
TL W P DGG + + + ++ + S + V+ + T F V+ L + Y F V
Sbjct: 29393 TLMWDAPLLDGGARIHHYVVEKR--EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 29450
Query: 532 AINK--IGQSKYRPDDTKAT 549
A+N+ +G+ P+ AT
Sbjct: 29451 AVNEYGVGEPYEMPEPIVAT 29470
Score = 60.9 bits (141), Expect = 2e-08
Identities = 63/236 (26%), Positives = 92/236 (38%), Gaps = 21/236 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFK-----PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVP 385
F+ N +G ++ +K K PE+D + K G RL + P
Sbjct: 19502 FRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRP 19561
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF 445
AP TW K G+ V + D + + L+I N D G Y N G
Sbjct: 19562 APKVTWRKVGIDNVVRKG--------QVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGE 19613
Query: 446 STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYK 503
V + V P V L V++VT ++ + W P DGG Q + Y + R+ D
Sbjct: 19614 KAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREA--DRKT 19671
Query: 504 YEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGE 558
+ V P+ T+F V L +Y F V A+N+ G P D L S + E
Sbjct: 19672 WSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGV--PTDVPKPVLASDPLSE 19725
Score = 60.5 bits (140), Expect = 2e-08
Identities = 78/364 (21%), Positives = 137/364 (37%), Gaps = 30/364 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSS--YSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
+++ R G+ P I+ W +DG I SS ++ + + LN++ L D GIYT
Sbjct: 7685 VVLECRVSGSAP-ISVGWFQDGNEIVSGPKCQSSFSENVCT----LNLSLLEPSDTGIYT 7739
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N G+ + ++V P + +V P + G P +KW +
Sbjct: 7740 CVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPF--KVKWFKG 7797
Query: 300 GYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
++ P +S ++ + L + + + G++ C+V N GSA+ + + K
Sbjct: 7798 SRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV---KEPA 7854
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
+ G L P S +W K+ +Y + IT
Sbjct: 7855 TFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKD----------EYLISQSERCSITM 7904
Query: 419 T---SVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLT-VTNVTHSTV 474
T ++L I DY Y C NE G + V P + L V V
Sbjct: 7905 TEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPA 7964
Query: 475 TLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAI 533
TL+ V G SWY+ + +YK + + + ++ ++ + +S A
Sbjct: 7965 TLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQ--FKNNVASLVINKVDHSDVGEYSCKAD 8022
Query: 534 NKIG 537
N +G
Sbjct: 8023 NSVG 8026
Score = 59.7 bits (138), Expect = 4e-08
Identities = 58/226 (25%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 321 IRKAKSENLGNFQ-CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKSAS-NVGQV 374
+ K K NF+ C +N+ G+G ++ + + PE++ + K
Sbjct: 25992 VTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT 26051
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
RL K P P W K L + + F ++L+I+NV D G
Sbjct: 26052 LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSF---------TMLVIDNVTRFDSGR 26102
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRI 492
Y N G T V + V +P V+LT+ V +VTL W P DGG + + Y +
Sbjct: 26103 YNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIV 26162
Query: 493 RYRKVFDDSY-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ +Y + K T F + L++ Y F V+A N+ G
Sbjct: 26163 EKRETTRKAYATITNNCTK--TTFRIENLQEGCSYYFRVLASNEYG 26206
Score = 59.3 bits (137), Expect = 6e-08
Identities = 54/226 (23%), Positives = 92/226 (40%), Gaps = 15/226 (6%)
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCT 283
L + + +G YTC N+ G A + V PA +K +S + V P + +L T
Sbjct: 6877 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSV-EPGKSIILEST 6935
Query: 284 AIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
G L + W++ G+ I + T L I + + G + C + N G
Sbjct: 6936 YTGT--LPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGR 6993
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
++ ++ P T +++A VG L C+ P + +W K KL
Sbjct: 6994 DVCGALVSTLE-PPYFVTELEPLEAA--VGDSVSLQCQVAGTPEITVSWYKGDTKL--RP 7048
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTT 448
+ +Y F N + L+ N V +D G Y C A N +G +++
Sbjct: 7049 TPEYRTYFTNN-----VATLVFNKVNINDSGEYTCKAENSIGTASS 7089
Score = 59.3 bits (137), Expect = 6e-08
Identities = 80/358 (22%), Positives = 139/358 (38%), Gaps = 24/358 (6%)
Query: 190 GNPPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGA 248
G PP +W KD + Y ++ ++ +LN+ D G Y C+A N G+
Sbjct: 8351 GTPP-FHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA---DIGEYQCKATNDVGS 8406
Query: 249 AVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKS 307
S+++ P ++ ++ L T G ++ + ++ KG + + +
Sbjct: 8407 DTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISV-VWFKDKGEIVRESDN 8465
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKS 367
+ + L + + N G + C + N G + +++ ++ P +K
Sbjct: 8466 IWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVE-KPESIKV 8524
Query: 368 ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNV 427
+ G L C P S W K+G +L + KY F S L I NV
Sbjct: 8525 TT--GDTCTLECTVAGTPELSTKWFKDGKEL--TSDNKYKISFFNK-----VSGLKIINV 8575
Query: 428 ATSDYGSYECGARNELGFSTTTVKLDV---TSAPDQVVSLTVTN-VTHSTVTLEW-VPGF 482
A SD G Y +N +G + T L V T P L TN ++ S+V +E V G
Sbjct: 8576 APSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGS 8635
Query: 483 DGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
SW+ KY+ L + TV+ LE++ ++ +A N G +
Sbjct: 8636 PPISVSWF--HEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDE 8691
Score = 58.8 bits (136), Expect = 7e-08
Identities = 51/187 (27%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
E D P F + VGQ ++ P P+ TW+K+G LP+ +T+ + D +
Sbjct: 24156 EPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTR----INVTDSL 24209
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVT 475
T+ L I D G Y N +G T ++++ PD + +V+ ++T
Sbjct: 24210 DLTT-LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 24268
Query: 476 LEWVPG-FDGGLQSWYRIRYRKVFDDSYKYEDVLPKHA--TNFTVHGLEKNTDYIFSVMA 532
L W P + GG Q I ++ D + DV+ T V L+ T+Y F + A
Sbjct: 24269 LSWNPPLYTGGCQITNYIVQKR--DTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFA 24326
Query: 533 INKIGQS 539
N+ GQS
Sbjct: 24327 ENRYGQS 24333
Score = 56.8 bits (131), Expect = 3e-07
Identities = 73/329 (22%), Positives = 129/329 (39%), Gaps = 30/329 (9%)
Query: 184 ISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAV 243
++ + G PP I TW + I +SS + + ++L +T + D+G Y CEA
Sbjct: 5246 LACKVTGTPP-IKITWFANDREIKESSKHRMS--FVESTAVLRLTDVGIEDSGEYMCEAQ 5302
Query: 244 NSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG--Y 301
N G+ + V V + + D +L G P I W +
Sbjct: 5303 NEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPF--EITWFKDNTIL 5360
Query: 302 KIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
+ K TF +L S L I K + + G +QC V N +GS+ I + +
Sbjct: 5361 RSGRKYKTFIQDHLVS-LQILKFVAADAGEYQCRVTNEVGSS-------ICSARVTLREP 5412
Query: 362 PNFVK---SASNV-GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
P+F+K S S++ G K + TW K+ ++ + + + F N
Sbjct: 5413 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIR--MTFENN---- 5466
Query: 418 YTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV---TSAPDQVVSLTVTNVTHSTV 474
+ L ++ + G Y C A+N+ G + L V + ++ VS+ VT +T+
Sbjct: 5467 -VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATL 5525
Query: 475 TLEWVPGFDGGLQSWYRIRYRKVFDDSYK 503
+++ G W++ YK
Sbjct: 5526 QVKF-SGTKEITAKWFKDGQELTLGSKYK 5553
Score = 56.8 bits (131), Expect = 3e-07
Identities = 71/329 (21%), Positives = 123/329 (37%), Gaps = 26/329 (7%)
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
I +++ M L+ D+G + CEA N G+ + V V P S V N +
Sbjct: 6402 IDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEV 6461
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C G P E + ++ K K KN + + I + ++G + C N
Sbjct: 6462 SLECELSGTPPF-EVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 6520
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKN 394
+GS T + VK K P FV +++ G+ L + W K
Sbjct: 6521 EVGSDT---CVCTVKLK----EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKE 6573
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFS---TTTVK 451
++ + S F +N + L ++ G Y C +N+ G T +
Sbjct: 6574 KEEV-IRESENIRITFVEN-----VATLQFAKAEPANAGKYICQIKNDGGMEENMATLMV 6627
Query: 452 LDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPK 510
L+ ++ +TVT T TLE V G WY + K+ S K++
Sbjct: 6628 LEPAVIVEKAGPMTVT--VGETCTLECKVAGTPELSVEWY--KDGKLLTSSQKHKFSFYN 6683
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQS 539
++ + +E+ ++ N +G+S
Sbjct: 6684 KISSLRILSVERQDAGTYTFQVQNNVGKS 6712
Score = 56.8 bits (131), Expect = 3e-07
Identities = 50/189 (26%), Positives = 69/189 (36%), Gaps = 13/189 (6%)
Query: 356 PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+ N + VG RL K VP P TW K P + D
Sbjct: 18143 PELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA---------RID 18193
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S L I N A D G Y N G T +VK+ V P L V+ + +
Sbjct: 18194 VTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSC 18253
Query: 475 TLEWVPGFD--GGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMA 532
L W D G + + Y + R V + K ++F H L + Y+F V A
Sbjct: 18254 YLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH-LNEGNQYLFRVAA 18312
Query: 533 INKIGQSKY 541
N+ G+ +
Sbjct: 18313 ENQYGRGPF 18321
Score = 56.4 bits (130), Expect = 4e-07
Identities = 57/252 (22%), Positives = 98/252 (38%), Gaps = 16/252 (6%)
Query: 231 TRHDAGIYTCEAVNSQG--AAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP 288
T G Y CEA+N G A A ++V IK + + A +C P
Sbjct: 4351 TEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAP 4410
Query: 289 LLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQD 347
+ +W + G +I + + S L I + + + G + C +N GS +
Sbjct: 4411 NV--RFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4468
Query: 348 VMLIVK-FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
+ + + + P + P + + VG+ + +C P W K+G L + S +
Sbjct: 4469 TLTVTEAYPPTFLSRPKSL--TTFVGKAAKFICTVTGTPVIETIWQKDGAAL--SPSPNW 4524
Query: 407 FAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL-T 465
+N HI L ++N+ D G Y C A N+ G +L + P + L
Sbjct: 4525 KISDAENKHI-----LELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEP 4579
Query: 466 VTNVTHSTVTLE 477
V + + V LE
Sbjct: 4580 VQSAINKKVHLE 4591
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G R + VP P+ W+ +G + + T Y E D+ ++SVL I N D
Sbjct: 18452 GTTVRFPAIIRGVPVPTAKWTTDGSE--IKTDEHYTVE---TDN--FSSVLTIKNCLRRD 18504
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQSW- 489
G Y+ N G T V L V P + + +VT +T+ W P D G
Sbjct: 18505 TGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVI 18564
Query: 490 -YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
Y + + D++ T + L+K +Y+F V A NKIG
Sbjct: 18565 NYIVEKQDTRKDTWGVVS-SGSSKTKLKIPHLQKGCEYVFRVRAENKIG 18612
Score = 56.0 bits (129), Expect = 5e-07
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 18/225 (8%)
Query: 321 IRKAKSENLGNFQ-CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKSAS-NVGQV 374
+ K ++ NF+ C +N G+G +IV+ K P++D K + G
Sbjct: 23827 VEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGS 23886
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
RL K P P W K V+ + A ++TS L+++NV D G
Sbjct: 23887 LRLFVPIKGRPTPEVKWGK------VDGEIRDAAIIDVTS--SFTS-LVLDNVNRYDSGK 23937
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRI 492
Y N G + V + V P V+L VT +T +V++ W P DGG + Y +
Sbjct: 23938 YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIV 23997
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ SY V H ++ + L++ Y F V A N+ G
Sbjct: 23998 EKREATRKSYA-AVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG 24041
Score = 55.6 bits (128), Expect = 7e-07
Identities = 50/170 (29%), Positives = 67/170 (39%), Gaps = 13/170 (7%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY-FAEFHKNDHITYTSVLLINNVATS 430
G+ RL P P+ WSK+G +L + A+F N L+N +T
Sbjct: 22403 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN---------LVNKDSTR 22453
Query: 431 -DYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQS 488
D G+Y A N GF+ + V P L VT VT L W P D G
Sbjct: 22454 RDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAK 22513
Query: 489 WYRIRYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
+K + +V + T V L K +YIF VMA+NK G
Sbjct: 22514 IDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYG 22563
Score = 54.8 bits (126), Expect = 1e-06
Identities = 75/347 (21%), Positives = 126/347 (36%), Gaps = 28/347 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P IT +W K + + + + L K+ +D+G YTC+A NS G A +
Sbjct: 7033 PEITVSWYKGDTKLRPTP--EYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSK 7090
Query: 253 ISVSVH---YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI--DPKS 307
+ P +++ L+C G+ + + W R G + D
Sbjct: 7091 TVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPI--QVCWYRDGVLLRDDENL 7148
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI--VKFKPEMDTSPNFV 365
T N+ + I++ S + G + C +N +G+A+ + K P D P +
Sbjct: 7149 QTSFVDNVATLKILQTDLSHS-GQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSI 7207
Query: 366 KSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLIN 425
+ G+ C TWSK+ + + Y N T L I
Sbjct: 7208 DVIA--GESADFECHVTGAQPMRITWSKDNKE--IRPGGNYTITCVGN-----TPHLRIL 7258
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGG 485
V D G Y C A N++G + +L V P V L + V +++ G
Sbjct: 7259 KVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGS 7318
Query: 486 LQ---SWYRIRYRKVFDDSYKYEDVLPKHATNFTVH--GLEKNTDYI 527
+ SW+ R +S+KY T++ E + DYI
Sbjct: 7319 PEIKVSWF--RNDSELHESWKYNMSFINSVALLTINEASAEDSGDYI 7363
Score = 54.8 bits (126), Expect = 1e-06
Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 6/166 (3%)
Query: 376 RLMCKCKSVPAPSFTWSKNG-VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
R+ K P P +W +G K + E + + +SV++I S G
Sbjct: 16756 RIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGK 16815
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRI 492
Y A+N+ G T ++ V P L V+++T + L W +P DGG + Y I
Sbjct: 16816 YSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVI 16875
Query: 493 RYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
R + D + V P +T F V L Y F V A N+ G
Sbjct: 16876 EKRTI--DGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG 16919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 76/338 (22%), Positives = 125/338 (36%), Gaps = 23/338 (6%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G PP TW K+ I S + DR+ L++TK D G Y C N G+
Sbjct: 5907 GTPP-FEVTWLKNNREIRSSKKYTLTDRVSVFN--LHITKCDPSDTGEYQCIVSNEGGSC 5963
Query: 250 VANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSV 308
+ V++ P +N A T G+P ++ I W + +D +V
Sbjct: 5964 SCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPIS--ITWLKDDQILDEDDNV 6021
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSA 368
+ + L IR + + G + C N G + L+V+ ++ V
Sbjct: 6022 YISFVDSVATLQIRSVDNGHSGRYTCQAKNESG-VERCYAFLLVQEPAQIVEKAKSVDVT 6080
Query: 369 SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVA 428
L C P W K+G ++ ++YF+ +N+ ++ I +V
Sbjct: 6081 EKDPMT--LECVVAGTPELKVKWLKDGKQI---VPSRYFSMSFENNVASFR----IQSVM 6131
Query: 429 TSDYGSYECGARNELGFSTTTV---KLDVTSAPDQVVSLT-VTNVTHSTVTLEW-VPGFD 483
D G Y N+ G S+ LD P LT + V S++ +E V G
Sbjct: 6132 KQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSL 6191
Query: 484 GGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLE 521
W+ + K S KY V + + + V+ LE
Sbjct: 6192 PISAQWF--KDGKEISTSAKYRLVCHERSVSLEVNNLE 6227
Score = 54.0 bits (124), Expect = 2e-06
Identities = 54/188 (28%), Positives = 83/188 (44%), Gaps = 16/188 (8%)
Query: 356 PEMDTSPNFVKSA-SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D S + G+ +++ K P P+ TW K+ L + +Y E
Sbjct: 28196 PEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL--GSDARYSIE----- 28248
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGF-STTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ +S+L I V +D G Y N +G ++TV + V P L V +V+ T
Sbjct: 28249 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGT 28308
Query: 474 VTLEWVPG-FDGGLQSWYRIRYRKVFDDSYKYEDVLPKH---ATNFTVHGLEKNTDYIFS 529
VTL W P DGG I Y D+ K + H +T+F + L + T + F
Sbjct: 28309 VTLLWDPPLIDGGSPI---INYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 28365
Query: 530 VMAINKIG 537
V+A N+IG
Sbjct: 28366 VLAENEIG 28373
Score = 53.6 bits (123), Expect = 3e-06
Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 19/232 (8%)
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS-------NV 371
L++ K F+ N G +V +++ K + SP+ AS +
Sbjct: 17407 LVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRL-VSPDLQLDASVRDRIVVHA 17465
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V R++ P P+ TW+ N LP + + A +S ++I N S
Sbjct: 17466 GGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTA---------ISSSMVIKNCQRSH 17516
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQV-VSLTVTNVTHSTVTLEWV-PGFDGGLQSW 489
G Y A+NE G T+ +DV P V N+T+ + L W P DGG
Sbjct: 17517 QGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPIT 17576
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ ++ D N TV GL + Y F + A N IG +
Sbjct: 17577 NYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPF 17628
Score = 53.2 bits (122), Expect = 4e-06
Identities = 42/154 (27%), Positives = 66/154 (42%), Gaps = 8/154 (5%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P TW+K + L + +++ S + I + SD G+Y A N G
Sbjct: 14645 PEPKITWTKADMILKQDKRITI-------ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 14697
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYK 503
+T V+++V P + +T+VT+ + L W P DGG + + R+ D
Sbjct: 14698 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVW 14757
Query: 504 YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
++ TNF L N +YIF V A N G
Sbjct: 14758 HKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 14791
Score = 52.8 bits (121), Expect = 5e-06
Identities = 54/205 (26%), Positives = 89/205 (43%), Gaps = 18/205 (8%)
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
++GI ++V IV+F PE +KS ++ R+ + P P TW K+GV
Sbjct: 28870 SSGIIMTRDENVPPIVEFGPEYFDGL-IIKSGESL----RIKALVQGRPVPRVTWFKDGV 28924
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
++ + + D + TS L + + G Y A+N G + +K+ V
Sbjct: 28925 EIEKRMNMEI------TDVLGSTS-LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 28977
Query: 457 APDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQ--SWYRIRYRKVFDDSYK-YEDVLPKHA 512
P +VV + TN+T +TL W + G + Y I R+ ++ ED A
Sbjct: 28978 TPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EA 29035
Query: 513 TNFTVHGLEKNTDYIFSVMAINKIG 537
++T L +Y F V A+NK G
Sbjct: 29036 QSYTAIKLINGNEYQFRVSAVNKFG 29060
Score = 52.4 bits (120), Expect = 6e-06
Identities = 80/390 (20%), Positives = 146/390 (37%), Gaps = 30/390 (7%)
Query: 160 VQNAPIFDDTTSYNTVGIENE-PLIISVRADGNPPSITYTWTKDGLPITQS-SYSSG-ND 216
V+ +P F T + + + E +++ G PP TW KD + Y + D
Sbjct: 5316 VKESPYF--TKEFKPIEVLKEYDVMLLAEVAGTPP-FEITWFKDNTILRSGRKYKTFIQD 5372
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
++S L + K DAG Y C N G+++ + V++ P ++ +
Sbjct: 5373 HLVS----LQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGG 5428
Query: 277 DAVLSCTAIGN-PLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
A T G+ P+ +K + + D +TFE + YL + K + G + C
Sbjct: 5429 TAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHD--GKYVCQ 5486
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G Q ++ K + V G L K + W K+G
Sbjct: 5487 AKNDAGI---QRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDG 5543
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVK---L 452
+L + +KY + D + S+L I + D G Y +N++G S+ + L
Sbjct: 5544 QELTL--GSKY--KISVTDTV---SILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVL 5596
Query: 453 DVTSAPDQVVSL-TVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK 510
D+ P L + ++ S + LE + + W++ + YK+
Sbjct: 5597 DLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFS--FHD 5654
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + LE ++ A NK G ++
Sbjct: 5655 NTAFLEISQLEGTDSGTYTCSATNKAGHNQ 5684
Score = 52.4 bits (120), Expect = 6e-06
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 13/171 (7%)
Query: 5 KDSGIFKCMINSPSDPPSA---------PMITGYVPGTTLAAGTVQKLACISTGGNPLAT 55
+D+G + C I + S S P + ++ G L C G P
Sbjct: 8860 EDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQC-QLAGTPEIG 8918
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTD--NQAQYRCEATNSATEIPLFETVTLN 113
++W+K D K+ TT + +++ N D + +Y C+A NS E+ +T+
Sbjct: 8919 VSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8978
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP 164
P + + G+ C + S + P ++SW++DG P++++P
Sbjct: 8979 EQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSP 9028
Score = 52.0 bits (119), Expect = 8e-06
Identities = 45/152 (29%), Positives = 70/152 (46%), Gaps = 8/152 (5%)
Query: 7 SGIFKCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIH 66
+G +C N P A + P L G +LAC TG P+ +TWF ND++I
Sbjct: 5211 AGGVECSANLFVKEP-ATFVEKLEPSQLLKKGDATQLACKVTGTPPIK-ITWFANDREIK 5268
Query: 67 STTKTTDKAV-SAEISILTNV-TDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVR 124
++K V S + LT+V ++ +Y CEA N A V V +P K
Sbjct: 5269 ESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI--VKESPYFTKEF 5326
Query: 125 AEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
+VLK + L+ + A + PP ++W++D
Sbjct: 5327 KPIEVLKE-YDVMLLAEVAGT-PPFEITWFKD 5356
Score = 52.0 bits (119), Expect = 8e-06
Identities = 53/204 (25%), Positives = 74/204 (36%), Gaps = 12/204 (5%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G RL K P P TWSK VN + + D T+ L NV D
Sbjct: 20635 GVTMRLYVPVKGRPPPKITWSKPN----VNLRDRIGLDIKSTDFDTF---LRCENVNKYD 20687
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSW- 489
G Y N G T+ + V P V++TV ++ + + W P DGG
Sbjct: 20688 AGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIIN 20747
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
Y ++ R S+ T+F V LE+ Y F V A N+ G P +T+
Sbjct: 20748 YVVQKRDAERKSWS-TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD--PGETRDA 20804
Query: 550 TLTSSEVGELSTVSTEYVETPDIS 573
S G + + V S
Sbjct: 20805 VKASQTPGPVVDLKVRSVSKSSCS 20828
Score = 51.6 bits (118), Expect = 1e-05
Identities = 52/213 (24%), Positives = 82/213 (38%), Gaps = 15/213 (7%)
Query: 332 FQCVVNNGIGSATKQDVMLIVK---FKPEMDTS--PNFVKSASNVGQVGRLMCKCKSVPA 386
F+ N G T ++ ++ + P++D P+ A RL K PA
Sbjct: 20880 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF-RLKIPIKGKPA 20938
Query: 387 PSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFS 446
PS +W K + P+ T T+ E + L++ + SD G Y +N G
Sbjct: 20939 PSVSWKKG--EDPLATDTRVSVE-----SSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 20991
Query: 447 TTTVKLDVTSAPD-QVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKVFDDSYKY 504
T+ + V P + VT +TL+W P DGG + I ++ ++
Sbjct: 20992 EGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWV 21051
Query: 505 EDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
T F V L + +Y F V A NK G
Sbjct: 21052 TCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 21084
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/164 (26%), Positives = 69/164 (42%), Gaps = 12/164 (7%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
RL K PAP W+++ + S + + + ++L++ NV D G Y
Sbjct: 22806 RLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY---------TLLIVGNVNRFDSGKY 22856
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRIR 493
N G + V + V P L V VT ++VTL W P DGG + Y +
Sbjct: 22857 ILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE 22916
Query: 494 YRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ +Y H T++ V L++ Y F V+A N+ G
Sbjct: 22917 KRESTRKAYS-TVATNCHKTSWKVDQLQEGCSYYFRVLAENEYG 22959
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/70 (35%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 472 STVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFS 529
+T+T+ WV P FDGG + Y + Y+K D +K + T +T+ GL +Y+F
Sbjct: 27025 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWK-TSIQSLRGTEYTISGLTTGAEYVFR 27083
Query: 530 VMAINKIGQS 539
V ++NK+G S
Sbjct: 27084 VKSVNKVGAS 27093
Score = 51.2 bits (117), Expect = 1e-05
Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 11/160 (6%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ TW K+ V P+ +T+ AE +N+ S+L I + D G Y N G
Sbjct: 23102 PTPAVTWHKDNV--PLKQTTRVNAESTENN-----SLLTIKDACREDVGHYVVKLTNSAG 23154
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
+ T+ + V P + + VT ++TL W P +DGG + Y + R +
Sbjct: 23155 EAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTT 23214
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
++ T L+ +Y F + A N+ G+S Y
Sbjct: 23215 WQIVSATVAR-TTIKACRLKTGCEYQFRIAAENRYGKSTY 23253
Score = 51.2 bits (117), Expect = 1e-05
Identities = 58/212 (27%), Positives = 81/212 (38%), Gaps = 19/212 (8%)
Query: 334 CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPS 388
C +N G+G AT + + K PE+D K G R+ K P P
Sbjct: 24923 CALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPE 24982
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTT 448
TWS+ ++ + + YT L I+N +D G Y N G +
Sbjct: 24983 ITWSRE--------EGEFTDKVQIEKGVNYTQ-LSIDNCDRNDAGKYILKLENSSGSKSA 25033
Query: 449 TVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRIRYRKVFDDSYKYED 506
V + V P +L V V + L W P DGG + Y I R+ Y +
Sbjct: 25034 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--STRKAYAN 25091
Query: 507 VLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
V K T+F V L + Y F VMA N+ G
Sbjct: 25092 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFG 25123
Score = 50.8 bits (116), Expect = 2e-05
Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 9/140 (6%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + P + G +L C G+P+ +TWFKN+K++ + V++
Sbjct: 4662 EPPS--FVKKVDPSYLMLPGESARLHC-KLKGSPVIQVTWFKNNKELSESNTVRMYFVNS 4718
Query: 79 E-ISILTNV-TDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEA 136
E I +T+V ++ Y CEA N + + P +K D+++ G A
Sbjct: 4719 EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE--PPSFIKTLEPADIVR-GTNA 4775
Query: 137 TLICDSASSNPPATLSWWRD 156
L C+ S P +SW++D
Sbjct: 4776 LLQCE-VSGTGPFEISWFKD 4794
Score = 50.4 bits (115), Expect = 3e-05
Identities = 54/220 (24%), Positives = 92/220 (41%), Gaps = 19/220 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFK-----PEMDTSPNFVKSASNV--GQVGRLMCKCKSV 384
F+ N G + ++++L V K PE+D NF V G ++
Sbjct: 27372 FRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK-NFPSHTVYVRAGSNLKVDIPISGK 27430
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL-INNVATSDYGSYECGARNEL 443
P P T S++GV P+ + ++ N IT ++ + + T+D G YE A N
Sbjct: 27431 PLPKVTLSRDGV--PLKATMRF------NTEITAENLTINLKESVTADAGRYEITAANSS 27482
Query: 444 GFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDS 501
G + + + V P + ++++T +VTL+W P +DGG Q I ++ +
Sbjct: 27483 GTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTA 27542
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
E T V L +Y F + A N+ G S +
Sbjct: 27543 VWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDH 27582
Score = 50.0 bits (114), Expect = 3e-05
Identities = 70/291 (24%), Positives = 116/291 (39%), Gaps = 21/291 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P ++ W KDG + S+ S + I++ + L + D G+Y+ E NS G +
Sbjct: 7599 PELSAKWFKDGREL--SADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 7656
Query: 253 ISVSVH---YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI--DPKS 307
+SV V P ++V A VL C G+ ++ + W + G +I PK
Sbjct: 7657 VSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPIS--VGWFQDGNEIVSGPKC 7714
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKS 367
+ +N+ + L + + + G + CV N GS + +L V+ P + +P+ V+
Sbjct: 7715 QSSFSENVCT-LNLSLLEPSDTGIYTCVAANVAGS-DECSAVLTVQEPPSFEQTPDSVEV 7772
Query: 368 ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNV 427
G + P W K +L S E D +T L + V
Sbjct: 7773 LP--GMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLE----DFVT---ELELFEV 7823
Query: 428 ATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV-THSTVTLE 477
+ G Y C N+ G ++ T L V V L +V T S + LE
Sbjct: 7824 QPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLE 7874
Score = 49.2 bits (112), Expect = 6e-05
Identities = 55/242 (22%), Positives = 96/242 (39%), Gaps = 15/242 (6%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT--KTTDKAVS 77
P + P + + T+ G L C G P T+TW++ D +I S+ + T ++
Sbjct: 939 PVTPPTLVSGLKNVTVIEGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGI 997
Query: 78 AEISILTNVTDNQAQYRCEATNSATEI--PLFETVTLNVHFAPEAVKVRAE-PDVLKPGI 134
A + I ++ ++ C A N A + + V ++ F E V + K +
Sbjct: 998 ARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFV 1057
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPS 194
E+ D ++ T G P AP F + +E ++ + GNP
Sbjct: 1058 ESR---DVVMTDTSLTEEQAGPGEPA--APYFITKPVVQKL-VEGGSVVFGCQVGGNPKP 1111
Query: 195 ITYTWTKDGLPITQS-SYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANI 253
Y W K G+P+T Y ++ E ++ ++ DAG YT N G A+
Sbjct: 1112 HVY-WKKSGVPLTTGYRYKVSYNKQTGECKLV-ISMTFADDAGEYTIVVRNKHGETSASA 1169
Query: 254 SV 255
S+
Sbjct: 1170 SL 1171
Score = 49.2 bits (112), Expect = 6e-05
Identities = 59/298 (19%), Positives = 109/298 (36%), Gaps = 16/298 (5%)
Query: 174 TVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRH 233
T G+ +++ + G+PP I+ +W +G I SS + L + L
Sbjct: 8618 TNGLSGSSVVMECKVYGSPP-ISVSWFHEGNEI--SSGRKYQTTLTDNTCALTVNMLEES 8674
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D+G YTC A N G+ + ++V P + + + G P +
Sbjct: 8675 DSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFS-- 8732
Query: 294 IKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W + ++ P ++ + L + + G + C+V+N G A+ L +
Sbjct: 8733 VSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKAS-CTTHLYI 8791
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
K + N + G+ L P S TW KNG +N +
Sbjct: 8792 KAPAKFVKRLN--DYSIEKGKPLILEGTFTGTPPISVTWKKNG----INVTPSQRCNITT 8845
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
+ +++L I + D G Y C N G + + ++ + P V L V+
Sbjct: 8846 TEK---SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVS 8900
Score = 49.2 bits (112), Expect = 6e-05
Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 382 KSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARN 441
K P + W K+G L T + T TS L I + D G+YE N
Sbjct: 26346 KGRPQATVNWRKDGQTLKETTRVNV------SSSKTVTS-LSIKEASKEDVGTYELCVSN 26398
Query: 442 ELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFD 499
G T + + V P + + V+ ++T+ W P +DGG Q S Y + ++
Sbjct: 26399 SAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTS 26458
Query: 500 DSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
++ T+ + L ++Y F V A N+ G+S Y
Sbjct: 26459 TTWHIVSQAVAR-TSIKIVRLTTGSEYQFRVCAENRYGKSSY 26499
Score = 48.8 bits (111), Expect = 8e-05
Identities = 53/185 (28%), Positives = 78/185 (42%), Gaps = 17/185 (9%)
Query: 277 DAVLSCTAIGNPLLAEHIKW--ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN-LGNFQ 333
D V T+I N A+ + W E K D K + +N T L+I K +E+ G +
Sbjct: 4304 DIVHLTTSITN---AKEVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYV 4359
Query: 334 CVVNNGIG-SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWS 392
C N G +AT + ++ + P + ++ A +G + + C+ +S P F W
Sbjct: 4360 CEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVA--LGHLAKFTCEIQSAPNVRFQWF 4417
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K G + + S K K Y S L I D G Y C A NE G + T L
Sbjct: 4418 KAGRE--IYESDKCSIRSSK-----YISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4470
Query: 453 DVTSA 457
VT A
Sbjct: 4471 TVTEA 4475
Score = 48.8 bits (111), Expect = 8e-05
Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 356 PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P F + N G+ RL P P+ W + ++ + E D
Sbjct: 24550 PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR----CEIKNTD 24605
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHST 473
+ ++L++ + D G Y A N G + V + V P + VT VT
Sbjct: 24606 ---FKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEK 24662
Query: 474 VTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATN-FTVHGLEKNTDYIFSV 530
+L W P DGG S Y + R+ + V + TN V L + +Y+F +
Sbjct: 24663 CSLTWSPPLQDGGSDISHYVVEKRET--SRLAWTVVASEVVTNSLKVTKLLEGNEYVFRI 24720
Query: 531 MAINKIG 537
MA+NK G
Sbjct: 24721 MAVNKYG 24727
Score = 48.8 bits (111), Expect = 8e-05
Identities = 49/171 (28%), Positives = 67/171 (39%), Gaps = 10/171 (5%)
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
+ G+ L + P P WSK+G +L A I T+ L++ +
Sbjct: 25647 HAGETFVLEADIRGKPIPDVVWSKDGKELEETA-----ARMEIKSTIQKTT-LVVKDCIR 25700
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGF-DGGLQ 487
+D G Y N G + + + V P L VT VT L W P DGG
Sbjct: 25701 TDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGAN 25760
Query: 488 -SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
S Y I R+ S+ A N+ V L +YIF VMA+NK G
Sbjct: 25761 ISHYIIEKRETSRLSWTQVST-EVQALNYKVTKLLPGNEYIFRVMAVNKYG 25810
Score = 48.8 bits (111), Expect = 8e-05
Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 13/157 (8%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
PAP+ W K+ +L N ++ T + +LI + + G YE RN +G
Sbjct: 27827 PAPTIEWYKDDKELQTNALVCV-------ENTTDLASILIKDADRLNSGCYELKLRNAMG 27879
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSY 502
++ T+++ + P + VT +TL W P DGG + + I ++ + S
Sbjct: 27880 SASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKR--ETSR 27937
Query: 503 KYEDVLPKHATN--FTVHGLEKNTDYIFSVMAINKIG 537
++ +H T + K +YIF V A+NK G
Sbjct: 27938 VVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYG 27974
Score = 48.0 bits (109), Expect = 1e-04
Identities = 63/261 (24%), Positives = 107/261 (40%), Gaps = 21/261 (8%)
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA-- 343
G+P L+ H++ KG D + V T Y++ R +++ + F+ N G +
Sbjct: 19056 GSPNLSYHVERRLKGSD-DWERVHKGSIKETHYMVDRCVENQ-IYEFRVQTKNEGGESDW 19113
Query: 344 --TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
T++ V+ KP +D + V + G RL + P P W+K+ +
Sbjct: 19114 VKTEEVVVKEDLQKPVLDLKLSGVLTVK-AGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 19172
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
S + K D +S + SD G Y A N G ++V P V
Sbjct: 19173 RSPRV-----KIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPV 19227
Query: 462 VSLTVTNVTHSTVTLEWVPGFDGG---LQSWY--RIRYRKVFDDSYKYEDVLPKHATNFT 516
+L + +V+ T+ W P D G +Q++ + +++ +Y + P T
Sbjct: 19228 RNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP----GTT 19283
Query: 517 VHGLEKNTDYIFSVMAINKIG 537
V L + +YIF V A NKIG
Sbjct: 19284 VTRLIEGNEYIFRVRAENKIG 19304
Score = 48.0 bits (109), Expect = 1e-04
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIR 493
A NE G + TT + + AP SL + ++T STV+L W P DGG + + Y I
Sbjct: 21870 AENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIE 21929
Query: 494 YRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
++ D + + + V L + +Y F VMA+N G+S R
Sbjct: 21930 AQRKGSDQWTH--ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR 21976
Score = 47.6 bits (108), Expect = 2e-04
Identities = 70/324 (21%), Positives = 115/324 (35%), Gaps = 22/324 (6%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS--YSSGNDRIISEGSMLNMTKL 230
NT G+ I+ + G+ P I+ W + I + ++ +D + + L + L
Sbjct: 6735 NTGGVLGASCILECKVAGSSP-ISVAWFHEKTKIVSGAKYQTTFSDNVCT----LQLNSL 6789
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGN-PL 289
D G YTC A N G+ ++V P + + P ++ + G P
Sbjct: 6790 DSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPF 6849
Query: 290 LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM 349
+ R+ K D ++ FE + + L + G + CVV+N G A+ +
Sbjct: 6850 KVNWFRGARELVKGDRCNIYFE--DTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRL 6907
Query: 350 LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
+ K + G+ L S TW K+G + TS K
Sbjct: 6908 FV---KEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFN--ITTSEKCNIV 6962
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL-TVTN 468
+ T +L I N D G Y C NE G + P V L +
Sbjct: 6963 TTEK-----TCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEA 7017
Query: 469 VTHSTVTLE-WVPGFDGGLQSWYR 491
+V+L+ V G SWY+
Sbjct: 7018 AVGDSVSLQCQVAGTPEITVSWYK 7041
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 7/133 (5%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVS--AEISILTNVTDNQAQYRCEATN 99
+L C G+P ++WF+ND ++H + K ++ A ++I ++ Y CEA N
Sbjct: 7310 QLEC-KISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHN 7368
Query: 100 SATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIP 159
+ +T+ AP + P G + L C+ S PP + W +D
Sbjct: 7369 GVGDASCSTALTVK---APPVFTQKPSPVGALKGSDVILQCE-ISGTPPFEVVWVKDRKQ 7424
Query: 160 VQNAPIFDDTTSY 172
V+N+ F T+ +
Sbjct: 7425 VRNSKKFKITSKH 7437
Score = 47.6 bits (108), Expect = 2e-04
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 4/159 (2%)
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
+P P WSKN + T + + T L I D G+Y A N L
Sbjct: 16352 LPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-LSIPKAVREDKGTYTVTASNRL 16410
Query: 444 GFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
G V ++V P +L VT++ + L W P +GG + + Y I R
Sbjct: 16411 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKK 16470
Query: 502 YKYEDVLPKHA-TNFTVHGLEKNTDYIFSVMAINKIGQS 539
++E+V + + L N Y F V A+NK G S
Sbjct: 16471 AEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGIS 16509
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/167 (26%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W K+G P+ +T+ E ++VL I D+G Y A N G
Sbjct: 25266 PRPNISWVKDGE--PLKQTTRVNVE-----ETATSTVLHIKEGNKDDFGKYTVTATNSAG 25318
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVP-GFDGGLQ-SWYRIRYRKVFDDS 501
+T + + V P V + V+ V + W P + GG Q S Y + R +
Sbjct: 25319 TATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTT 25378
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKA 548
+ T + L+ T+Y F + A N+ G+S P D+KA
Sbjct: 25379 WHMVSATVARTT-IKITKLKTGTEYQFRIFAENRYGKS--APLDSKA 25422
Score = 46.4 bits (105), Expect = 4e-04
Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 11/148 (7%)
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF------STTTVKLDVT 455
T +K +A K+ YT + + + Y + A NE+G S D
Sbjct: 17979 TMSKRWARVTKDPIHPYTKFRVPDLLEGCQY-EFRVSAENEIGIGDPSPPSKPVFAKDPI 18037
Query: 456 SAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHA- 512
+ P V+ + T ++V L W P DGG + Y + Y+KV D+ ++ + P+
Sbjct: 18038 AKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCP 18097
Query: 513 -TNFTVHGLEKNTDYIFSVMAINKIGQS 539
T + V GL Y F V+A+N G+S
Sbjct: 18098 ETKYKVTGLRDGQTYKFRVLAVNAAGES 18125
Score = 45.6 bits (103), Expect = 7e-04
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Query: 172 YNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTK 229
+NT I+ E L I + G P P+I+ W KDG P+ Q++ + + S ++L++ +
Sbjct: 25245 FNTYSIQAGEDLKIEIPVIGRPRPNIS--WVKDGEPLKQTTRVNVEETATS--TVLHIKE 25300
Query: 230 LTRHDAGIYTCEAVNSQGAAVANISVSV 257
+ D G YT A NS G A N+SV V
Sbjct: 25301 GNKDDFGKYTVTATNSAGTATENLSVIV 25328
Score = 45.2 bits (102), Expect = 0.001
Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLN 226
D +++ + IE E L I V P T +W KDG + S + ND I + L
Sbjct: 15317 DLETHDIIVIEGEKLSIPVPFRAVPVP-TVSWHKDGKEVKASDRLTMKNDHISAH---LE 15372
Query: 227 MTKLTRHDAGIYTCEAVNSQGAAVANISVSV 257
+ K R DAGIYT N G+A A+I+V V
Sbjct: 15373 VPKSVRADAGIYTITLENKLGSATASINVKV 15403
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 17/125 (13%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVH-------------YPAGIKSVSQNVVANPNEDAVL 280
DA +YTCEA N G A + S+SV YP I + Q+ V + + A
Sbjct: 3305 DAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARF 3364
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSY-LIIRKAKSENLGNFQCVVNNG 339
C G L + W K KI P + +Y L I +A E+ G + V +N
Sbjct: 3365 QCRVSGTDL---KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNA 3421
Query: 340 IGSAT 344
+G +
Sbjct: 3422 VGQVS 3426
Score = 44.8 bits (101), Expect = 0.001
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 6/148 (4%)
Query: 395 GVKLPVNTSTKYFAEFHKN----DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
G +P TK E K+ D++ S L+I + D+G Y A N G
Sbjct: 16057 GRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAA 16116
Query: 451 KLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKVFDDSYKYEDVLP 509
+++V P V+ L L W P DGG + I RK + + +
Sbjct: 16117 RVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERK-DAKMHTWRQPIE 16175
Query: 510 KHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ + GL + +Y F V+A NK G
Sbjct: 16176 TERSKCDITGLLEGQEYKFRVIAKNKFG 16203
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRI 492
+ CG E+G + +D P LT T T ST+TL+W P +GG Y I
Sbjct: 16202 FGCGPPVEIG---PILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 16258
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
R+ ++ + T+F V L+++ Y F V A+N+IG+S+
Sbjct: 16259 EKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 16306
Score = 44.8 bits (101), Expect = 0.001
Identities = 41/170 (24%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G+V ++ P P +W+K+G+++ T+ + ++H ++L + + D
Sbjct: 26731 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEIIST---DNH----TLLTVKDCIRRD 26783
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWV-PGFDGGLQ-S 488
G Y +N G + V V P L + +T +L W P DGG
Sbjct: 26784 TGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 26843
Query: 489 WYRIRYRKVFDDSYKY-EDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+Y + R+ ++ E L T+ V L K +YIF V +NK G
Sbjct: 26844 YYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYG 26891
Score = 44.4 bits (100), Expect = 0.002
Identities = 39/156 (25%), Positives = 60/156 (38%), Gaps = 12/156 (7%)
Query: 306 KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD-TSPNF 364
+ + E K +S + + + + Q N + + KF E + T P F
Sbjct: 3446 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIF 3505
Query: 365 VKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
+K SN +G V L +P P W NGV L + K+ F +DH
Sbjct: 3506 IKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFV--FDGDDH----- 3558
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L+I D G Y C A N+ G + + L + S
Sbjct: 3559 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3594
Score = 44.4 bits (100), Expect = 0.002
Identities = 40/169 (23%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSA 78
+AP+I + +A G + K C P WFK ++I+ + K + K +S+
Sbjct: 4381 AAPVIKRKIEPLEVALGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4439
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
+ T V D +Y C+A+N + T+T+ + P + R + G A
Sbjct: 4440 LEILRTQVVDC-GEYTCKASNEYGSVSCTATLTVTEAYPPTFLS-RPKSLTTFVGKAAKF 4497
Query: 139 ICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVR 187
IC + + P W +DG + +P + + + N +E L I R
Sbjct: 4498 IC-TVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDR 4545
Score = 44.4 bits (100), Expect = 0.002
Identities = 85/372 (22%), Positives = 144/372 (38%), Gaps = 38/372 (10%)
Query: 190 GNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGA 248
G P P + +T KD +T+S + R ++ S ++TK R D G Y A N+ G+
Sbjct: 19154 GKPFPEVAWTKDKDATDLTRSPRVKIDTR--ADSSKFSLTKAKRSDGGKYVVTATNTAGS 19211
Query: 249 AVANISVSV-HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGY---KID 304
VA +V+V P ++++ + + + D CT +P + E + Y K +
Sbjct: 19212 FVAYATVNVLDKPGPVRNLK---IVDVSSD---RCTVCWDP-PEDDGGCEIQNYILEKCE 19264
Query: 305 PKSV---TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA-TKQDVMLIVKFKPEMDT 360
K + T+ LT + + N F+ N IG+ + +I K K +
Sbjct: 19265 TKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPG 19324
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF-HKNDHITYT 419
P+ V +V + P P + K+ + K+ + N
Sbjct: 19325 RPD----PPEVTKVSKEEMTVVWNP-PEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE 19379
Query: 420 SVLLINNVATSDYGSYECGARNELGF------STTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ + N+ + A NE+G S V D P + V + T +
Sbjct: 19380 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHS 19439
Query: 474 VTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHAT------NFTVHGLEKNTD 525
+TL W P +DGG Y + R D+ E +A FTV L++N +
Sbjct: 19440 ITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 19499
Query: 526 YIFSVMAINKIG 537
Y F V A N++G
Sbjct: 19500 YEFRVCAQNQVG 19511
Score = 44.4 bits (100), Expect = 0.002
Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 16/161 (9%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P +WSK G + + T+ + +S+L I D G Y A N G
Sbjct: 21334 PLPKSSWSKAGKDIRPSDITQITST-------PTSSMLTIKYATRKDAGEYTITATNPFG 21386
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSY 502
VK+ V P + ++NV+ TL W P DGG Y + R+ +
Sbjct: 21387 TKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLW 21446
Query: 503 KY--EDVLP-KHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
ED+ +H + G +YIF V A+N G+ +
Sbjct: 21447 TVVSEDIQSCRHVATKLIQG----NEYIFRVSAVNHYGKGE 21483
Score = 44.4 bits (100), Expect = 0.002
Identities = 60/227 (26%), Positives = 88/227 (38%), Gaps = 18/227 (7%)
Query: 320 IIRKAKSENLGNFQCVVNNGIG-SATKQDVMLIVKFK---PEMDTSPNFVKSA-SNVGQV 374
++R FQ + N G SA ++ +IVK + PE+D + K + G
Sbjct: 21950 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDN 22009
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL-INNVATSDYG 433
++ P P+ TW K G ++ T F T TS +L IN SD G
Sbjct: 22010 IKVEIPVLGRPKPTVTWKK-GDQILKQTQRVNF-------ETTATSTILNINECVRSDSG 22061
Query: 434 SYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWY 490
Y ARN +G + + V P + V+ VT W P DGG+ S Y
Sbjct: 22062 PYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNY 22121
Query: 491 RIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ R+ D + E T + L +Y F V A N+ G
Sbjct: 22122 VVEMRQT-DSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 22167
Score = 44.0 bits (99), Expect = 0.002
Identities = 53/215 (24%), Positives = 85/215 (39%), Gaps = 20/215 (9%)
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS---VTFEPKNLTSYLIIRKA 324
Q+VV A G P+ + W R G I + V + + L I
Sbjct: 13 QSVVVLEGSTATFEAHISGFPV--PEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAV 70
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCK 380
N G + NG G AT +L+ K E PNFV+ ++ G RL +
Sbjct: 71 TKANSGRYSLKATNGSGQATSTAELLV---KAET-APPNFVQRLQSMTVRQGSQVRLQVR 126
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
+P P + ++G ++ S+ F + D Y+ LLI D G+Y A
Sbjct: 127 VTGIPTPVVKFYRDGAEIQ---SSLDFQISQEGD--LYS--LLIAEAYPEDSGTYSVNAT 179
Query: 441 NELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVT 475
N +G +T+T +L V + T T V+ + ++
Sbjct: 180 NSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQIS 214
Score = 43.6 bits (98), Expect = 0.003
Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHA--TNFTVHGLE 521
V + T S+V+L W P +DGG Y + ++ D++ + LP++ T F V GL
Sbjct: 20524 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCN-LPQNLQKTRFEVTGLM 20582
Query: 522 KNTDYIFSVMAINKIGQS 539
++T Y F V A+NKIG S
Sbjct: 20583 EDTQYQFRVYAVNKIGYS 20600
Score = 43.6 bits (98), Expect = 0.003
Identities = 40/155 (25%), Positives = 63/155 (40%), Gaps = 12/155 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ WSK L T+ + D + L I N +D G Y +N L
Sbjct: 27141 PVPNVLWSKPDTDL----RTRAYV-----DTTDSRTSLTIENANRNDSGKYTLTIQNVLS 27191
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSY 502
++ T+ + V P ++TV +VT + L W VP DGG Y I R+ ++
Sbjct: 27192 AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAW 27251
Query: 503 KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ ++ V L++ Y F V N+ G
Sbjct: 27252 -VSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFG 27285
Score = 43.2 bits (97), Expect = 0.004
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Query: 456 SAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHAT 513
+ P++ L V VT +TVTL W P +DGG + Y + R + + + +
Sbjct: 17642 TVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSR 17701
Query: 514 NFTVHGLEKNTDYIFSVMAINKIGQSK 540
+TV GL++ Y + V A+N +GQ K
Sbjct: 17702 KYTVKGLKEGDTYEYRVSAVNIVGQGK 17728
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 12/156 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W K+G L K + +N L + +V D G Y A N G
Sbjct: 20250 PMPTVSWKKDGTLLKPAEGIKMAMQ--RN-----LCTLELFSVNRKDSGDYTITAENSSG 20302
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSY 502
+ T+KL V P S+ + + L W P DGG + + Y + R+ ++
Sbjct: 20303 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 20362
Query: 503 -KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ +P T+ +V L + +Y F + A NK G
Sbjct: 20363 AQVSATVP--ITSCSVEKLIEGHEYQFRICAENKYG 20396
Score = 42.7 bits (96), Expect = 0.005
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 9/113 (7%)
Query: 49 GGNPLATLTWFKNDKKIHSTTKTT----DKAVSAEISILTNVTDNQAQYRCEATNSATEI 104
GG T+ WFK++K++HS + D + S E+ TD+ Y C+ +N
Sbjct: 5719 GGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLEL-FAAKATDS-GTYICQLSNDVGTA 5776
Query: 105 PLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
TL V P+ +K + VL+ G T C + P +SW+ DG
Sbjct: 5777 T--SKATLFVKEPPQFIKKPSPVLVLRNGQSTTFEC-QITGTPKIRVSWYLDG 5826
Score = 42.7 bits (96), Expect = 0.005
Identities = 31/80 (38%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 464 LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLE 521
L V N+T +T L+W VP DGG + Y + R V ++ D K T TV L
Sbjct: 15017 LEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLT 15075
Query: 522 KNTDYIFSVMAINKIGQSKY 541
+ + Y+F V A N IGQS Y
Sbjct: 15076 EGSLYVFRVAAENAIGQSDY 15095
Score = 42.7 bits (96), Expect = 0.005
Identities = 49/226 (21%), Positives = 88/226 (38%), Gaps = 11/226 (4%)
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV--GQVGR 376
L++ K F+ N +G + ++ + + K ++ + + G+ R
Sbjct: 19785 LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLR 19844
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
+ P P+ W K ++ ++ + A HK D +S+L+I +V D G Y
Sbjct: 19845 IEAHVYGKPHPTCKWKKGEDEV---VTSSHLA-VHKADS---SSILIIKDVTRKDSGYYS 19897
Query: 437 CGARNELGFSTTTVKLDVTSAP-DQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRY 494
A N G T +K+ V AP ++++ +L W +P DGG I
Sbjct: 19898 LTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVE 19957
Query: 495 RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + T+ V L +YIF V A N+ G S+
Sbjct: 19958 KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 20003
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 4/125 (3%)
Query: 36 AAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVT--DNQAQY 93
A G L C G P T++W+K D K+ T + + +++ N ++ +Y
Sbjct: 7018 AVGDSVSLQC-QVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEY 7076
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSW 153
C+A NS + P + + + G+ TL C + + P + W
Sbjct: 7077 TCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTC-RLNGSAPIQVCW 7135
Query: 154 WRDGI 158
+RDG+
Sbjct: 7136 YRDGV 7140
Score = 42.3 bits (95), Expect = 0.007
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 469 VTHSTVTLEWV-PGFDGG-LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDY 526
V + +TL+W P +DGG + + Y + R + D + T FTV GL ++ Y
Sbjct: 24459 VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRY 24518
Query: 527 IFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVIVYVSLTGAV 586
F V+A N G +P D+ EV EL +S + P ++V T +
Sbjct: 24519 EFRVIAKNAAGAIS-KPSDSTGPITAKDEV-ELPRISMD----PKFRDTIVVNAGETFRL 24572
Query: 587 LVLINVALIACFVWKRRLRRIKEQA 611
++ + W R + I+E A
Sbjct: 24573 EADVHGKPLPTIEWLRGDKEIEESA 24597
Score = 42.3 bits (95), Expect = 0.007
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIR 493
A NE G + TT + V+ P +T+ +VT +T T++W P DGG + + Y +
Sbjct: 26201 ASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVE 26260
Query: 494 YRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
+ S K+ T+ GL +Y+F V A+N+ G+S R
Sbjct: 26261 MQT--KGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPR 26307
Score = 42.3 bits (95), Expect = 0.007
Identities = 54/192 (28%), Positives = 77/192 (40%), Gaps = 18/192 (9%)
Query: 356 PEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D S + +G L K P PS +W K+G LP+ S F F K +
Sbjct: 28488 PEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDG--LPLKESE--FVRFSKTE 28543
Query: 415 HITYTSVLLINNVATSDYGSYECGARN---ELGFSTTTVKLDVTSAPDQVVSLTVTNVTH 471
+ L I N G Y N + T + L S P + +
Sbjct: 28544 N---KITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRF--DEIKA 28598
Query: 472 STVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA-TNFTVHGLEKNTDYIF 528
+V L W VP +GG + + Y I R+ ++K V A T F V L K+ +Y F
Sbjct: 28599 DSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKM--VCSSVARTTFKVPNLVKDAEYQF 28656
Query: 529 SVMAINKIGQSK 540
V A N+ G S+
Sbjct: 28657 RVRAENRYGVSQ 28668
Score = 41.9 bits (94), Expect = 0.009
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYKYEDVLPK 510
D S PD L VT +T ++ TL W+P DGG + Y YR+ + ++ +
Sbjct: 19721 DPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV 19780
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ V GL++ Y F V A N +G S
Sbjct: 19781 KDLSLVVTGLKEGKKYKFRVAARNAVGVS 19809
Score = 41.5 bits (93), Expect = 0.012
Identities = 44/156 (28%), Positives = 63/156 (40%), Gaps = 11/156 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ W K +L NT+ E D T SV + D G+Y A+N G
Sbjct: 23498 PIPTIQWIKGDQELS-NTAR---LEIKSTDFATSLSV---KDAVRVDSGNYILKAKNVAG 23550
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGF-DGGLQSW-YRIRYRKVFDDS 501
+ TV + V P + ++ VT TL W P DGG Y + R+
Sbjct: 23551 ERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLV 23610
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ D + + LE N +Y F +MA+NK G
Sbjct: 23611 WTVVDANVQTLSCKVTKLLEGN-EYTFRIMAVNKYG 23645
Score = 41.1 bits (92), Expect = 0.016
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 10/125 (8%)
Query: 424 INNVATSDYGSYECGARNELGF-----STTTVKL-DVTSAPDQVVSLTVTNVTHSTVTLE 477
+ +V S+ A+N +G +T VK+ D P V+LT ++ T S+V L+
Sbjct: 14179 VTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLK 14238
Query: 478 WVPGF-DGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAIN 534
W P DGG + + R + D+ + L T + V GLEK Y++ V A N
Sbjct: 14239 WEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELT-YKVTGLEKGNKYLYRVSAEN 14297
Query: 535 KIGQS 539
K G S
Sbjct: 14298 KAGVS 14302
Score = 41.1 bits (92), Expect = 0.016
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 5/108 (4%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRY 494
A NE G + T + V P +TV +VT ++V+L W P DGG + I
Sbjct: 24036 AENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVE 24095
Query: 495 RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
+ S K+ + + + L + +Y+F V+A+N+ G+S R
Sbjct: 24096 MQA-KHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 24142
Score = 40.7 bits (91), Expect = 0.021
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 49 GGNPLATLTWFKNDKKIHSTTKTTDKAV-SAEISILTNVT-DNQAQYRCEATNSATEIPL 106
GG+P + W+K++ +I ++K V S + + N++ ++ Y CEA N+A
Sbjct: 8257 GGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSAS- 8315
Query: 107 FETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
+ +L V P + + P G + L C+ PP +SW++D
Sbjct: 8316 -SSTSLKVK-EPPIFRKKPHPIETLKGADVHLECE-LQGTPPFHVSWYKD 8362
Score = 40.7 bits (91), Expect = 0.021
Identities = 34/156 (21%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 45 CISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEISILTNVTDNQAQYRCEATNSAT 102
C TG P+ ++W K+ ++I S K + SA +++L + QY C A N
Sbjct: 9101 CHVTGTQPIK-VSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVG 9159
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQN 162
+ + + P + R V + + + + + P T++W+++ I +Q
Sbjct: 9160 KDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQ- 9218
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYT 198
TS + +N L++ VR G + YT
Sbjct: 9219 ------PTSNCEITFKNNTLVLQVRKAGMNDAGLYT 9248
Score = 40.7 bits (91), Expect = 0.021
Identities = 39/129 (30%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGF-----STTTVKLDVTSAPDQVVSLTVTNVTH 471
+YT++ LIN ++Y + A N+ G S V + PD +N+T
Sbjct: 29037 SYTAIKLING---NEY-QFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITG 29092
Query: 472 STVTLEWV-PGFDGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIF 528
+++TL W P DGG +Q + R K K P T F V GL + +Y F
Sbjct: 29093 NSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEF 29152
Query: 529 SVMAINKIG 537
VMA N G
Sbjct: 29153 HVMAENAAG 29161
Score = 40.3 bits (90), Expect = 0.028
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 13/158 (8%)
Query: 3 SKKDSGIFKCMIN-SPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKN 61
++ D+G C I +PP+ I P + V+ L C TG P +TW KN
Sbjct: 5863 ARNDAGTASCSIELKVKEPPT--FIRELKPVEVVKYSDVE-LECEVTGTPPFE-VTWLKN 5918
Query: 62 DKKIHSTTK--TTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE 119
+++I S+ K TD+ + I + +Y+C +N V L P
Sbjct: 5919 NREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE--PPS 5976
Query: 120 AV-KVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
+ K+ VLK + + + +PP +++W +D
Sbjct: 5977 FIKKIENTTTVLK---SSATFQSTVAGSPPISITWLKD 6011
Score = 39.9 bits (89), Expect = 0.037
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L+I+ SD G Y N + + + ++V + P L ++T +V L W P
Sbjct: 14379 LVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPP 14438
Query: 482 FD--GGLQSWYRIRYRKVFDDSY-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
D G + Y + R+V ++ K D + FTV L + +Y+F V A NK G
Sbjct: 14439 DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTD--LEFTVPDLVQGKEYLFKVCARNKCG 14495
Score = 39.9 bits (89), Expect = 0.037
Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 180 EPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
E L I G P P +T W KDG+ I + D + S + L + TR G+Y
Sbjct: 28901 ESLRIKALVQGRPVPRVT--WFKDGVEIEKRMNMEITDVLGS--TSLFVRDATRDHRGVY 28956
Query: 239 TCEAVNSQGAAVANISVSVHYPAG 262
T EA N+ G+A A I V V G
Sbjct: 28957 TVEAKNASGSAKAEIKVKVQDTPG 28980
Score = 39.5 bits (88), Expect = 0.048
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 172 YNTVGI-ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTK 229
+NT + E L + V G P P++T W KD +P+ Q+ + N S+L +
Sbjct: 23081 FNTFTVLAGEDLKVDVPFIGRPTPAVT--WHKDNVPLKQT--TRVNAESTENNSLLTIKD 23136
Query: 230 LTRHDAGIYTCEAVNSQGAAVANISVSV 257
R D G Y + NS G A+ ++V V
Sbjct: 23137 ACREDVGHYVVKLTNSAGEAIETLNVIV 23164
Score = 39.5 bits (88), Expect = 0.048
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
+ L I V G P T TWTKDGLP+ Q++ + D + + + L++ + + D G Y
Sbjct: 24172 QDLKIEVPISGRPKP-TITWTKDGLPLKQTTRINVTDSL--DLTTLSIKETHKDDGGQYG 24228
Query: 240 CEAVNSQGAAVANISV 255
N G A+I +
Sbjct: 24229 ITVANVVGQKTASIEI 24244
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/123 (30%), Positives = 53/123 (43%), Gaps = 11/123 (8%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT----DKAVSAEISILTNVTDNQAQY 93
G+ L CI G +P++ + WFK+D++I ++ K D EIS L TD+ Y
Sbjct: 5616 GSFIDLECIVAGSHPIS-IQWFKDDQEISASEKYKFSFHDNTAFLEISQLEG-TDS-GTY 5672
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSW 153
C ATN A + L V P V+ DV P L P T+ W
Sbjct: 5673 TCSATNKAGHNQC--SGHLTVKEPPYFVEKPQSQDV-NPNTRVQLKA-LVGGTAPMTIKW 5728
Query: 154 WRD 156
++D
Sbjct: 5729 FKD 5731
Score = 39.1 bits (87), Expect = 0.064
Identities = 82/387 (21%), Positives = 146/387 (37%), Gaps = 30/387 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
E + G PP T W+KDG + ++ +I + L TR D+G YT
Sbjct: 22404 EAFRLEADVSGRPPP-TMEWSKDGKELEGTAKLE--IKIADFSTNLVNKDSTRRDSGAYT 22460
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAI---GNPLLAEHIKW 296
A N G A +V V G V +E VLS G + +I
Sbjct: 22461 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 22520
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAK-SENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+R+ ++ +V E + +T + + K +E + V G+G + + +L V
Sbjct: 22521 KRETSRLAWTNVASEVQ-VTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVN-- 22577
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P P + + + ++C P + V K + K +
Sbjct: 22578 PYGPPDPPKNPEVTTITKDSMVVCWGH----PDSDGGSEIINYIVERRDKAGQRWIKCNK 22633
Query: 416 ITYTSVLL-INNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV------SLTVTN 468
T T + ++ + + A N G S + A D V + V +
Sbjct: 22634 KTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLD 22693
Query: 469 VTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK---HATNFTVHGLEKN 523
+ S++++ W P +DGG + + Y + +D ++ V P AT++T+ GL +N
Sbjct: 22694 TSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI--VTPPAGLKATSYTITGLTEN 22751
Query: 524 TDYIFSVMAINK--IGQSKYRPDDTKA 548
+Y + A+N +G+ P KA
Sbjct: 22752 QEYKIRIYAMNSEGLGEPALVPGTPKA 22778
Score = 38.7 bits (86), Expect = 0.084
Identities = 46/196 (23%), Positives = 79/196 (40%), Gaps = 14/196 (7%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISE 221
AP F + V +E G P P ++ W +DG I+ S+ G S+
Sbjct: 5 APTFTQPLQ-SVVVLEGSTATFEAHISGFPVPEVS--WFRDGQVISTSTL-PGVQISFSD 60
Query: 222 G-SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH---YPAGIKSVSQNVVANPNED 277
G + L + +T+ ++G Y+ +A N G A + + V P Q++
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQ 120
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE--PKNLTSYLIIRKAKSENLGNFQCV 335
L G P +K+ R G +I S+ F+ + L+I +A E+ G +
Sbjct: 121 VRLQVRVTGIP--TPVVKFYRDGAEIQ-SSLDFQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 336 VNNGIGSATKQDVMLI 351
N +G AT +L+
Sbjct: 178 ATNSVGRATSTAELLV 193
Score = 38.7 bits (86), Expect = 0.084
Identities = 59/216 (27%), Positives = 81/216 (37%), Gaps = 32/216 (14%)
Query: 260 PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSY 318
P IK VS N + + A LS T IG P I+W G + P + F
Sbjct: 3503 PIFIKEVS-NADISMGDVATLSVTVIGIP--KPKIQWFFNGVLLTPSADYKFVFDGDDHS 3559
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI-VKFKPEMDTS---------------- 361
LII K E+ G + C+ +N G + I K + DT
Sbjct: 3560 LIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 3619
Query: 362 -PNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
P+F+K + G PAP+ TW K +L TS Y + N
Sbjct: 3620 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLC--TSVYYTIIHNPNGSG 3677
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
T+ ++N+ D G Y C A N LG ST +L
Sbjct: 3678 TF----IVNDPQREDSGLYICKAENMLGESTCAAEL 3709
Score = 37.9 bits (84), Expect = 0.15
Identities = 58/269 (21%), Positives = 101/269 (37%), Gaps = 19/269 (7%)
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L T G P+ + W++ G + P + + + L + ++ G++ N
Sbjct: 20242 LDATVFGKPMPT--VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 20299
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
GS + + L V KP S K S+ R M + + N +
Sbjct: 20300 SSGSKSAT-IKLKVLDKPGPPASVKINKMYSD-----RAMLSWEPPLEDGGSEITNYIVD 20353
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG-----FSTTTVKLD 453
TS +A+ IT SV + + +Y C A N+ G F+ + +
Sbjct: 20354 KRETSRPNWAQVSATVPITSCSVEKL--IEGHEYQFRIC-AENKYGVGDPVFTEPAIAKN 20410
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ--SWYRIRYRKVFDDSYKYEDVLPKH 511
P + ++N+T +T+ W P D G + Y + R+ ++ + P
Sbjct: 20411 PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPII 20470
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
GL++ T+Y F V AINK G K
Sbjct: 20471 ERTLKATGLQEGTEYEFRVTAINKAGPGK 20499
Score = 37.9 bits (84), Expect = 0.15
Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 10/128 (7%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKY-EDVLPKHATNFTVHGLEK 522
VT+ + S+V+L W P +DGG Y + ++ D + FTV L++
Sbjct: 25938 VTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKE 25997
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVIVYVSL 582
NT+Y F + AIN G + TL S V + E D+ K V++ S
Sbjct: 25998 NTEYNFRICAINSEGVG-------EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 26050
Query: 583 TGAVLVLI 590
T + V I
Sbjct: 26051 TLRLFVTI 26058
Score = 37.9 bits (84), Expect = 0.15
Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 458 PDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHATNF 515
P VV +T T+ T TV+LEW P FDGG++ Y I K + + T +
Sbjct: 29183 PPTVVKVTDTSKT--TVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRY 29240
Query: 516 TVHGLEKNTDYIFSVMAINKIGQ 538
TV L+ +Y F V AIN G+
Sbjct: 29241 TVTDLQAGEEYKFRVSAINGAGK 29263
Score = 37.5 bits (83), Expect = 0.19
Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 8/173 (4%)
Query: 4 KKDSGIFKCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDK 63
K D+G+ +C P A +I P T+ G L C+ TG P + WFK+ +
Sbjct: 7554 KNDAGMRECSAVLTVLEP-ARIIEKPEP-MTVTTGNPFALECVVTG-TPELSAKWFKDGR 7610
Query: 64 KIHSTTKTTDKAVS--AEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAV 121
++ + +K ++ A + I ++ Y E NS + +V ++ P +
Sbjct: 7611 ELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSF 7670
Query: 122 KVRAEPDVLKP-GIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYN 173
+R DV G L C S + P ++ W++DG + + P + S N
Sbjct: 7671 -IRKLKDVNAILGASVVLEC-RVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN 7721
Score = 37.5 bits (83), Expect = 0.19
Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 12/161 (7%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
GQ + C+ SVP W +NG L K E HK +T I +V D
Sbjct: 9686 GQTCTMTCQF-SVPNVKSEWFRNGRILKPQGRHKTEVE-HKVHKLT------IADVRAED 9737
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYR 491
G Y C + + ++ + ++ ++ V+ H + T E FD + +WY
Sbjct: 9738 QGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSE--HQSATFECEVSFDDAIVTWY- 9794
Query: 492 IRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMA 532
+ +S KY T+H + + + ++SV+A
Sbjct: 9795 -KGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 9834
Score = 37.5 bits (83), Expect = 0.19
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 5/126 (3%)
Query: 446 STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYK 503
S + LD P + V L N+T TVTL+W P + GG + + Y + R + + +
Sbjct: 22275 SEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWL 22331
Query: 504 YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVS 563
+ FTV GL ++ Y F V+A N G + + A T V
Sbjct: 22332 KANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVD 22391
Query: 564 TEYVET 569
++ +T
Sbjct: 22392 VKFKDT 22397
Score = 37.1 bits (82), Expect = 0.26
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL-----TVTNVTHSTVTLEWVPGF-D 483
SDY + A N G ++ D +A D + VT+ T S+ LEW P D
Sbjct: 17316 SDY-QFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKD 17374
Query: 484 GGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
GG + + Y + Y++ + ++ T V GL++ Y F V A+N G
Sbjct: 17375 GGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVSAVNIAG 17429
Score = 36.7 bits (81), Expect = 0.34
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 6/107 (5%)
Query: 438 GARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRIRYR 495
G + + D PD V + V N T +T+ W P +DGG + Y I
Sbjct: 15487 GGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKI 15546
Query: 496 KVFDDSYK--YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
++ +K E ++P +T GLE+ +Y F V A N G S+
Sbjct: 15547 AKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGISE 15591
Score = 36.7 bits (81), Expect = 0.34
Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V APD+ TV++VT +++T+ W P +DGG + Y + + +K + P
Sbjct: 17243 VPGAPDKP---TVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIK 17299
Query: 512 A----TNFTVHGLEKNTDYIFSVMAINKIG 537
A ++ V GL + +DY F V AIN G
Sbjct: 17300 AMTLGVSYKVTGLIEGSDYQFRVYAINAAG 17329
Score = 36.3 bits (80), Expect = 0.45
Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 7/122 (5%)
Query: 37 AGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTN--VTDNQAQYR 94
AG +L C G+P + WF+N+ ++ ++ K + + I N T++ +
Sbjct: 6364 AGDSSRLEC-KIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFI 6422
Query: 95 CEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWW 154
CEA N A V V P + LK E +L C+ S PP + W+
Sbjct: 6423 CEAQNPAGSTSCSTKVI--VKEPPVFSSFPPIVETLK-NAEVSLECE-LSGTPPFEVVWY 6478
Query: 155 RD 156
+D
Sbjct: 6479 KD 6480
Score = 36.3 bits (80), Expect = 0.45
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 19/122 (15%)
Query: 137 TLICDSASSNPPATLS-WWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSI 195
T+IC P L +DG+ ++ DT N + I +PL P S
Sbjct: 21293 TIICKDEYEAPTIVLDPTIKDGLTIKAG----DTIVLNAISILGKPL---------PKS- 21338
Query: 196 TYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
+W+K G I S + S SML + TR DAG YT A N G V ++ V
Sbjct: 21339 --SWSKAGKDIRPSDITQITSTPTS--SMLTIKYATRKDAGEYTITATNPFGTKVEHVKV 21394
Query: 256 SV 257
+V
Sbjct: 21395 TV 21396
Score = 35.9 bits (79), Expect = 0.60
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 465 TVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSY-KYEDVLPKHATNFTVHGLE 521
TV +V ++V L W P DGG + Y I K D + + + +P T + GL
Sbjct: 14918 TVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVP--TTQHLLPGLM 14975
Query: 522 KNTDYIFSVMAINKIGQSK 540
+ +Y F V A+NK G+S+
Sbjct: 14976 EGQEYSFRVRAVNKAGESE 14994
Score = 35.9 bits (79), Expect = 0.60
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 32 GTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHST--TKTTDKAVSAEISILTNVTDN 89
G T+ AG L IS G PL +W K K I + T+ T S+ ++I +
Sbjct: 21314 GLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKD 21373
Query: 90 QAQYRCEATNS-ATEIPLFETVTLNVHFAPEAVKV 123
+Y ATN T++ + L+V P V++
Sbjct: 21374 AGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEI 21408
Score = 35.9 bits (79), Expect = 0.60
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 11/100 (11%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT----KTTDK 74
DPP M Y + AG K+ G P+ T+ W K D+++ +T K+TD
Sbjct: 23466 DPPRISMDPKYKDTIVVHAGESFKVDA-DIYGKPIPTIQWIKGDQELSNTARLEIKSTDF 23524
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
A S +S+ V + Y +A N A E +VT+NV
Sbjct: 23525 ATS--LSVKDAVRVDSGNYILKAKNVAGE----RSVTVNV 23558
Score = 35.9 bits (79), Expect = 0.60
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK 510
D P + + + T S++TL W P +DGG + Y + R+ ++ + +
Sbjct: 28089 DPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGE 28148
Query: 511 -HATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
T + V L+ +Y F V A+N GQ +
Sbjct: 28149 VRTTEYVVSNLKPGVNYYFRVSAVNCAGQGE 28179
Score = 35.5 bits (78), Expect = 0.79
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 8/137 (5%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTK---TTDKAVSAEI 80
PMI + T G + L T + W+ +K + S K D+ +
Sbjct: 4289 PMIHTPLVDTVSEEGDIVHLTTSITNAKEV---NWYFENKLVPSDEKFKCLQDQNTYTLV 4345
Query: 81 SILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLIC 140
N D+Q +Y CEA N + + +T+ AP +K + EP + G A C
Sbjct: 4346 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP-VIKRKIEPLEVALGHLAKFTC 4404
Query: 141 DSASSNPPATLSWWRDG 157
+ S+ P W++ G
Sbjct: 4405 EIQSA-PNVRFQWFKAG 4420
Score = 35.5 bits (78), Expect = 0.79
Identities = 33/176 (18%), Positives = 66/176 (37%), Gaps = 6/176 (3%)
Query: 4 KKDSGIFKCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDK 63
K D+G+ +C P+ I + G L C + G P + WFK+ K
Sbjct: 8495 KNDAGMQECFATLSVLEPAT--IVEKPESIKVTTGDTCTLEC-TVAGTPELSTKWFKDGK 8551
Query: 64 KIHSTTKTTDKAVS--AEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAV 121
++ S K + + + I+ + Y E N + ++ ++ P +
Sbjct: 8552 ELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSF 8611
Query: 122 KVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGI 177
+ + G + C S PP ++SW+ +G + + + T + NT +
Sbjct: 8612 TRKLKETNGLSGSSVVMECKVYGS-PPISVSWFHEGNEISSGRKYQTTLTDNTCAL 8666
Score = 35.5 bits (78), Expect = 0.79
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
VTN+T +V+L+W P +DGG + + Y + R++ D + + T F V L ++
Sbjct: 26620 VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 26679
Query: 524 TDYIFSVMAINKIGQSKYRPDDTKATTLTSSEV 556
Y F V A N S P ++ + +V
Sbjct: 26680 QRYEFRVFARN-AADSVSEPSESTGPIIVKDDV 26711
Score = 34.7 bits (76), Expect = 1.4
Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 13/116 (11%)
Query: 58 WFKNDKKIHSTTKTT--DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
WFKND+++H+T + D+ + I+ D+ +Q R EA ++E L + + +
Sbjct: 12888 WFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKL-TVLEGDPY 12946
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG---IPVQNAPIFDD 168
F K++ V K E L C+ + ++ P + W++DG P +NA I D
Sbjct: 12947 FTG---KLQDYTGVEKD--EVILQCEISKADAP--VKWFKDGKEIKPSKNAVIKAD 12995
Score = 34.7 bits (76), Expect = 1.4
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 9/94 (9%)
Query: 451 KLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVL 508
K DV P +++T+T+V V+L W P +DGG + + Y I R S +++ +
Sbjct: 14114 KYDVPGPP---LNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRD--KTSIRWDTAM 14168
Query: 509 PKHATNF--TVHGLEKNTDYIFSVMAINKIGQSK 540
A + TV + + +Y F V A N+IG K
Sbjct: 14169 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGK 14202
Score = 34.7 bits (76), Expect = 1.4
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 455 TSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA 512
T P L V + + S+ L W+ P DGG + + Y + R+ D + E K
Sbjct: 29470 TEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHTKQL 29528
Query: 513 TNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
T FTV L + T+Y F V A N G S+ R
Sbjct: 29529 T-FTVERLVEKTEYEFRVKAKNDAGYSEPR 29557
Score = 34.3 bits (75), Expect = 1.8
Identities = 66/301 (21%), Positives = 110/301 (36%), Gaps = 36/301 (11%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P IT W KD + + ++ T+++ DAG YT A G V+
Sbjct: 3084 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMS--DAGKYTVVA----GGNVST 3137
Query: 253 ISVSVH-YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID---PKSV 308
+ V I+S+ + V + AV+ + + A W + G +I+ +
Sbjct: 3138 AKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAH---WYKDGIEINFQVQERH 3194
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DTSPNFVK 366
+ + + I + + + G + V S T + + P++ + P V+
Sbjct: 3195 KYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT---LYVNAPEPPQVLQELQPVTVQ 3251
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
S G+ R P P +W K L K+ +D YT LL+
Sbjct: 3252 S----GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-----HDGQEYT--LLLIE 3300
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDV----TSAPDQ---VVSLTVTNVTHSTVTLEWV 479
D Y C A+N+ G +TT+ L V +PDQ V + TVT E
Sbjct: 3301 AFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQ 3360
Query: 480 P 480
P
Sbjct: 3361 P 3361
Score = 34.3 bits (75), Expect = 1.8
Identities = 25/121 (20%), Positives = 48/121 (39%), Gaps = 3/121 (2%)
Query: 420 SVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV 479
S L + + D+G Y N+ G + + V P ++ ++ ++V +W
Sbjct: 15691 SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWE 15750
Query: 480 PGFDGG---LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKI 536
P D G + ++ + K DS ++V L + +Y+F V A N+
Sbjct: 15751 PPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 15810
Query: 537 G 537
G
Sbjct: 15811 G 15811
Score = 34.3 bits (75), Expect = 1.8
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPK 510
D P + + + T +++TL W P +DGG + Y + K D +++ V P+
Sbjct: 24842 DPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA--DEEEWQIVTPQ 24899
Query: 511 ---HATNFTVHGLEKNTDYIFSVMAINKIG 537
T F + L ++ +Y V A+NK+G
Sbjct: 24900 TGLRVTRFEISKLTEHQEYKIRVCALNKVG 24929
Score = 33.5 bits (73), Expect = 3.2
Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 11/99 (11%)
Query: 360 TSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
T P V NV G+ L C P+P+ TW + + + +S + F
Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQ--IESSIDFQITFQSG-- 996
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ L+I D G + C A NE G +T+ L V
Sbjct: 997 ---IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 33.5 bits (73), Expect = 3.2
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C+ P P W K+GV P+ T +Y ++K T L+I+ D G Y
Sbjct: 1103 CQVGGNPKPHVYWKKSGV--PLTTGYRYKVSYNKQ---TGECKLVISMTFADDAGEYTIV 1157
Query: 439 ARNELGFSTTTVKL 452
RN+ G ++ + L
Sbjct: 1158 VRNKHGETSASASL 1171
Score = 33.5 bits (73), Expect = 3.2
Identities = 41/189 (21%), Positives = 77/189 (40%), Gaps = 16/189 (8%)
Query: 1 MYSKKDSGIFKCMINSP--SDPPSAPMITGYVPGTT-------LAAGTVQKLACISTGGN 51
M + DSG + C+ + SD SAP+ P + GT I G
Sbjct: 8670 MLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTP 8729
Query: 52 PLATLTWFKNDKKIHSTTKTTDKAVS--AEISILTNVTDNQAQYRCEATNSATEIPLFET 109
P + ++WFK ++ + AE+ + T +Y C +N A + T
Sbjct: 8730 PFS-VSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASC--T 8786
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDT 169
L + + VK R ++ G + ++ + + PP +++W ++GI V + + T
Sbjct: 8787 THLYIKAPAKFVK-RLNDYSIEKG-KPLILEGTFTGTPPISVTWKKNGINVTPSQRCNIT 8844
Query: 170 TSYNTVGIE 178
T+ + +E
Sbjct: 8845 TTEKSAILE 8853
Score = 33.5 bits (73), Expect = 3.2
Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 7/99 (7%)
Query: 449 TVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQSWYRIRYRKVFD------DS 501
T D PD + L + +T +TV L W P DGG + I +D ++
Sbjct: 16930 TTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEA 16989
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
++ + FTV L + +Y F V A+N G SK
Sbjct: 16990 WRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSK 17028
Score = 33.5 bits (73), Expect = 3.2
Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 5/86 (5%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA 512
V APDQ + VT VT + + W DGG + Y + R+ + P H
Sbjct: 17938 VPDAPDQPI---VTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHP 17994
Query: 513 -TNFTVHGLEKNTDYIFSVMAINKIG 537
T F V L + Y F V A N+IG
Sbjct: 17995 YTKFRVPDLLEGCQYEFRVSAENEIG 18020
Score = 33.5 bits (73), Expect = 3.2
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK--HATNFTVHGLE 521
VT +T +++T+ W P DGG S Y + R S + VL + T V GL
Sbjct: 28001 VTKITKNSMTVVWSRPIADGGSDISGYFLEKRD--KKSLGWFKVLKETIRDTRQKVTGLT 28058
Query: 522 KNTDYIFSVMAINKIGQSKY 541
+N+DY + V A+N GQ +
Sbjct: 28059 ENSDYQYRVCAVNAAGQGPF 28078
Score = 33.5 bits (73), Expect = 3.2
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKK 64
+ SGI M + PP Y G + +G ++ + G P+ +TWFK+ +
Sbjct: 28869 QSSGII--MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL-VQGRPVPRVTWFKDGVE 28925
Query: 65 IHS--TTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
I + TD S + + D++ Y EA N++
Sbjct: 28926 IEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 28964
Score = 33.1 bits (72), Expect = 4.2
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 414 DHITYTSVLLINNVATSDY-GSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHS 472
D TYT L+I+ V T D+ G Y C A N+ G + T+ KL V V+ + +
Sbjct: 4338 DQNTYT--LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPL--- 4392
Query: 473 TVTLEWVPGFDGGLQSWYRIRYR 495
V L + F +QS +R++
Sbjct: 4393 EVALGHLAKFTCEIQSAPNVRFQ 4415
Score = 33.1 bits (72), Expect = 4.2
Identities = 28/109 (25%), Positives = 44/109 (40%), Gaps = 6/109 (5%)
Query: 50 GNPLATLTWFKNDKKIHS--TTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
G P +TWFK++ + S KT + + IL V + +Y+C TN
Sbjct: 5345 GTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICS 5404
Query: 108 ETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
VTL P +K L+ G A + + P T++W +D
Sbjct: 5405 ARVTLRE--PPSFIKKIESTSSLRGGTAA--FQATLKGSLPITVTWLKD 5449
Score = 33.1 bits (72), Expect = 4.2
Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRK----VFDDSYKYEDVLPKHATNFTVHGL 520
VT+VT STV+L W P +DGG + I RK V D + + FTV L
Sbjct: 29874 VTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTAL 29933
Query: 521 EKNTDYIFSVMAINKIG 537
+ Y F V+A N G
Sbjct: 29934 SEGDTYEFRVLAKNAAG 29950
Score = 32.7 bits (71), Expect = 5.5
Identities = 57/249 (22%), Positives = 94/249 (37%), Gaps = 25/249 (10%)
Query: 218 IISEGS--MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPN 275
+I++G +L + T D G Y V GAA A ++V I ++
Sbjct: 13526 VIADGKKRVLVVKDATLQDMGTY----VVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQ 13581
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
++ V +C A KW R I D K+L L IR A ++ N+
Sbjct: 13582 QEVVFNCEVNTEGAKA---KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNV 13638
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSK 393
+ N G K LIV+ + P +K + + CK + + W+K
Sbjct: 13639 SLTNHRGENVKSAANLIVEEEDLRIVEP--LKDIETMEKKSVTFWCKVNRLNV-TLKWTK 13695
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
NG ++P + Y + +K+ +L I + D G Y A G + +L
Sbjct: 13696 NGEEVPFDNRVSYRVDKYKH-------MLTIKDCGFPDEGEYIVTA----GQDKSVAELL 13744
Query: 454 VTSAPDQVV 462
+ AP + V
Sbjct: 13745 IIEAPTEFV 13753
Score = 32.3 bits (70), Expect = 7.3
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Query: 466 VTNVTHSTVTLEWVP-GFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
VT+ + +T+ LEW P F+GG + Y + + V + + +TV + +
Sbjct: 15937 VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREG 15996
Query: 524 TDYIFSVMAINKIGQSKYRPDDTKATTLTSSE 555
DY V A+N G+ P +T+ T+ +
Sbjct: 15997 ADYKLRVSAVNAAGEGP--PGETQPVTVAEPQ 16026
Score = 32.3 bits (70), Expect = 7.3
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
V+NVT +T T+ W P DGG + + Y + R+ + P V GL++
Sbjct: 21507 VSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEG 21566
Query: 524 TDYIFSVMAINKIG 537
+ Y F V A N+ G
Sbjct: 21567 STYEFRVSAENRAG 21580
Score = 32.3 bits (70), Expect = 7.3
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 11/135 (8%)
Query: 130 LKPGIE---ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT--VGIENEPLII 184
LKPG+ + A P ++ + AP D + T + E + +
Sbjct: 28159 LKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQV 28218
Query: 185 SVRADGNPPSITYTWTKDGLPI-TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAV 243
+ G PP T TW KD + + + YS N S+L + ++TR+D G Y
Sbjct: 28219 LIPFKGRPPP-TVTWRKDEKNLGSDARYSIENT---DSSSLLTIPQVTRNDTGKYILTIE 28274
Query: 244 NSQGAAVAN-ISVSV 257
N G ++ +SV V
Sbjct: 28275 NGVGEPKSSTVSVKV 28289
Score = 31.9 bits (69), Expect = 9.7
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TWTK + + Q + + + + S + + R D G Y EAVN G A A
Sbjct: 14645 PEPKITWTKADMILKQDKRITIEN--VPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAV 14702
Query: 253 ISVSV 257
+ V+V
Sbjct: 14703 VEVNV 14707
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 87.4 bits (207), Expect = 2e-16
Identities = 77/291 (26%), Positives = 127/291 (43%), Gaps = 26/291 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P I W KDG ++ S +D +L ++ LT D G+Y+C+A N GA +
Sbjct: 243 PVIETIWQKDGAALSPSPNWRISDA--ENKHILELSNLTIQDRGVYSCKASNKFGADICQ 300
Query: 253 IS-VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS---V 308
+ + P IK + + V + N+ L C + + + W + G K+ P +
Sbjct: 301 AELIIIDKPHFIKEL-EPVQSAINKKVHLECQVDEDRKVT--VTWSKDGQKLPPGKDYKI 357
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DTSPNFVK 366
FE K T L I AK ++ G + C +N GS++ + V+ P P+++
Sbjct: 358 CFEDKIAT--LEIPLAKLKDSGTYVCTASNEAGSSSCS-ATVTVREPPSFVKKVDPSYLM 414
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV-NTSTKYFAEFHKNDHITYTSVLLIN 425
G+ RL CK K P TW KN +L NT YF + ++L I
Sbjct: 415 LP---GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF--------VNSEAILDIT 463
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTL 476
+V D GSY C A N++G + + ++ + P + +L ++ T L
Sbjct: 464 DVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNAL 514
Score = 87.4 bits (207), Expect = 2e-16
Identities = 75/275 (27%), Positives = 118/275 (42%), Gaps = 20/275 (7%)
Query: 198 TWTKDGLPITQSSYSSGNDRIISEGSM--LNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
TW+KD I GN I G+ L + K+ + D+G YTC+A N G + + +
Sbjct: 2968 TWSKDNKEIRPG----GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 3023
Query: 256 SVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPK 313
SV P +K + + VA E L C G+P + + W R ++ +
Sbjct: 3024 SVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEI--KVSWFRNDSELHESWKYNMSFI 3081
Query: 314 NLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQ 373
N + L I +A +E+ G++ C +NG+G A+ L VK P P+ V +
Sbjct: 3082 NSVALLTINEASAEDSGDYICEAHNGVGDAS-CSTALTVKAPPVFTQKPSPVGALKGSDV 3140
Query: 374 VGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYG 433
+ L C+ P W K+ + V S K+ K + + L I N+ SD G
Sbjct: 3141 I--LQCEISGTPPFEVVWVKD--RKQVRNSKKF-----KITSKHFDTNLHILNLEASDVG 3191
Query: 434 SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
Y C A NE+G T + + P V L+ T+
Sbjct: 3192 EYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTS 3226
Score = 81.0 bits (191), Expect = 2e-14
Identities = 81/324 (25%), Positives = 135/324 (41%), Gaps = 30/324 (9%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G P I W KD I +SS + + ++L M L+ D+G YTCEA N+ G+A
Sbjct: 3995 GGSPEIKVLWYKDETEIQESSKFRMS--FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSA 4052
Query: 250 VANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSV 308
++ S+ V P + + D L C G P H+ W + ++ K
Sbjct: 4053 SSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPF--HVSWYKDKRELRSGKKY 4110
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSA 368
+N + + I + ++G +QC N +GS T + + P FVK
Sbjct: 4111 KIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSI-------ALKAPPRFVKKL 4163
Query: 369 SN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLI 424
S+ VG+ +L + S W K+ ++ V S + + +N + L
Sbjct: 4164 SDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEI-VRESDNIWISYSEN-----IATLQF 4217
Query: 425 NNVATSDYGSYECGARNELG----FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLE-WV 479
+ V ++ G Y C +N+ G F+T +V L+ + ++ S+ VT T T TLE V
Sbjct: 4218 SRVEPANAGKYTCQIKNDAGMQECFATLSV-LEPATIVEKPESIKVT--TGDTCTLECTV 4274
Query: 480 PGFDGGLQSWYRIRYRKVFDDSYK 503
G W++ D+ YK
Sbjct: 4275 AGTPELSTKWFKDGKELTSDNKYK 4298
Score = 80.2 bits (189), Expect = 3e-14
Identities = 67/273 (24%), Positives = 112/273 (41%), Gaps = 13/273 (4%)
Query: 181 PLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTC 240
P+++ G PP I+ +W KD I+QS S + + ++L + + T D Y+C
Sbjct: 3608 PIVLEATYTGTPP-ISVSWIKDEYLISQSERCSIT--MTEKSTILEILESTIEDYAQYSC 3664
Query: 241 EAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
N G + VSV P ++V A E A L C G P + I W ++
Sbjct: 3665 LIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEI--RISWYKEH 3722
Query: 301 YKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
K+ + + KN + L+I K ++G + C +N +G+ V++I K
Sbjct: 3723 TKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPF 3782
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
+ +G C+ +W K+GV L + + + F N
Sbjct: 3783 FARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQ--TSFVHN-----V 3835
Query: 420 SVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
+ L I S G Y C A N LG ++++ KL
Sbjct: 3836 ATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 3868
Score = 78.6 bits (185), Expect = 9e-14
Identities = 71/277 (25%), Positives = 113/277 (40%), Gaps = 23/277 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
+I+ G P I+ TW KDG IT S N + +L + T+ DAG Y+CE
Sbjct: 2668 IILESTYTGTLP-ISVTWKKDGFNITTSEKC--NIVTTEKTCILEILNSTKRDAGQYSCE 2724
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGY 301
N G V VS P + + + A + L C G P + + W +
Sbjct: 2725 IENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEIT--VSWYKGDT 2782
Query: 302 KI--DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
K+ P+ T+ N+ + L+ K + G + C N IG+A+ + V I E
Sbjct: 2783 KLRPTPEYRTYFTNNVAT-LVFNKVNINDSGEYTCKAENSIGTASSKTVFRI----QERQ 2837
Query: 360 TSPNFVKSASNVGQ-VG---RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P+F + ++ Q VG L C+ W ++GV L + E +
Sbjct: 2838 LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDH-------ENLQTSF 2890
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
+ + L I S G Y C A N LG ++++ +L
Sbjct: 2891 VDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 2927
Score = 78.6 bits (185), Expect = 9e-14
Identities = 82/308 (26%), Positives = 126/308 (40%), Gaps = 28/308 (9%)
Query: 161 QNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRI-- 218
+N P FD + + E G P I +W KD I S G +I
Sbjct: 4815 KNPPFFDIRLA-PVDAVVGESADFECHVTGTQP-IKVSWAKDSREIR----SGGKYQISY 4868
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQG----AAVANISVSVHYPAGIKSVSQNVVANP 274
+ + L + K+ + D+G YTC AVN G A NI + P+ K +S+ V
Sbjct: 4869 LENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETE 4928
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS---VTFEPKNLTSYLIIRKAKSENLGN 331
L G+ + + W + +I P S +TF KN T L +RKA + G
Sbjct: 4929 GNSFKLEGRVAGSQPIT--VAWYKNNIEIQPTSNCEITF--KNNTLVLQVRKAGMNDAGL 4984
Query: 332 FQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW 391
+ C V+N GSA ++I + K + + G+ +L C + W
Sbjct: 4985 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQW 5044
Query: 392 SKNGVKL-PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
K G ++ P + + FA + T+VL + +VA +D G Y C A N G TT
Sbjct: 5045 LKAGREIKPSDRCSFSFA--------SGTAVLELRDVAKADSGDYVCKASNVAGSDTTKS 5096
Query: 451 KLDVTSAP 458
K+ + P
Sbjct: 5097 KVTIKDKP 5104
Score = 77.8 bits (183), Expect = 1e-13
Identities = 82/373 (21%), Positives = 143/373 (38%), Gaps = 21/373 (5%)
Query: 173 NTVGIEN-EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT 231
N IE +PLI+ G PP I+ TW K+G+ +T S N + +L + T
Sbjct: 4540 NDYSIEKGKPLILEGTFTGTPP-ISVTWKKNGINVTPSQRC--NITTTEKSPILEIPSST 4596
Query: 232 RHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA 291
DAG Y C N+ G + + + P + V + + A L C G P +
Sbjct: 4597 VEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIG 4656
Query: 292 EHIKWERKGYKIDPKSV-TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
+ W + K+ P + +N + L+ + + G + C N +G + +
Sbjct: 4657 --VSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT 4714
Query: 351 IVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
+ + K S VG C S +W K+G P+ S F
Sbjct: 4715 VQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDG--KPLKDSPNVQTSF 4772
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD----QVVSLTV 466
N T+ L I S G Y C A N +G ++++ +L +T + + V
Sbjct: 4773 LDN-----TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPV 4827
Query: 467 TNVTHSTVTLE-WVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTD 525
V + E V G SW + + KY+ +++ + TV ++K
Sbjct: 4828 DAVVGESADFECHVTGTQPIKVSW--AKDSREIRSGGKYQISYLENSAHLTVLKVDKGDS 4885
Query: 526 YIFSVMAINKIGQ 538
++ A+N++G+
Sbjct: 4886 GQYTCYAVNEVGK 4898
Score = 75.8 bits (178), Expect = 6e-13
Identities = 75/273 (27%), Positives = 118/273 (43%), Gaps = 19/273 (6%)
Query: 193 PSITYTWTKDGLPITQSSYSS-GNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG--AA 249
P++ + W K G I +S S + + IS +L T++ D G YTC+A N G +
Sbjct: 148 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR-TQVV--DCGEYTCKASNEYGSVSC 204
Query: 250 VANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK-SV 308
A ++V+ YP S +++ + A CT G P++ E I W++ G + P +
Sbjct: 205 TATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVI-ETI-WQKDGAALSPSPNW 262
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSA 368
L + ++ G + C +N G+ Q ++I+ KP V+SA
Sbjct: 263 RISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIID-KPHFIKELEPVQSA 321
Query: 369 SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVA 428
N + L C+ + TWSK+G KLP K E D I + L I
Sbjct: 322 IN--KKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFE----DKI---ATLEIPLAK 372
Query: 429 TSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
D G+Y C A NE G S+ + + V P V
Sbjct: 373 LKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 405
Score = 75.8 bits (178), Expect = 6e-13
Identities = 76/300 (25%), Positives = 128/300 (42%), Gaps = 31/300 (10%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS--YSSGNDRIISEGSMLNMTKL 230
NT + G+PP I+ TW KD + + Y S D + + L + +
Sbjct: 1721 NTTTVLKSSATFQSTVAGSPP-ISITWLKDDQILDEDDNVYISFVDSVAT----LQIRSV 1775
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLL 290
+G YTC+A N G + V PA I +++V + L C G P L
Sbjct: 1776 DNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPEL 1835
Query: 291 AEHIKWERKGYKIDPK---SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQD 347
+KW + G +I P S++FE N+ S+ I+ ++ G + V N GS++
Sbjct: 1836 --KVKWLKDGKQIVPSRYFSMSFE-NNVASFR-IQSVMKQDSGQYTFKVENDFGSSSCDA 1891
Query: 348 VMLIVKFKPEMDTSPNFVKSASNVGQV--GRLMCKCK---SVPAPSFTWSKNGVKLPVNT 402
+ ++ + + P+F K + + +V + +CK S+P S W K+G + ++T
Sbjct: 1892 YLRVL----DQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPI-SAQWFKDGKE--IST 1944
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
S KY H+ + L +NN+ D +Y C N G + L V P +V
Sbjct: 1945 SAKYRLVCHER-----SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLV 1999
Score = 74.9 bits (176), Expect = 1e-12
Identities = 74/290 (25%), Positives = 122/290 (42%), Gaps = 16/290 (5%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G+ P I+ W KD I+ S + + L +++L D+G YTC A N G
Sbjct: 1365 GSHP-ISIQWFKDDQEISASEKYKFSFH--DNTAFLEISQLEGTDSGTYTCSATNKAGHN 1421
Query: 250 VANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVT 309
+ ++V P Q+ NPN L G + IKW + ++ +
Sbjct: 1422 QCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMT--IKWFKDNKELHSGAAR 1479
Query: 310 FEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSA 368
K+ TS L + AK+ + G + C ++N +G+AT + L VK P+ P+ V
Sbjct: 1480 SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKPSPVLVL 1538
Query: 369 SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVA 428
N GQ C+ P +W +G ++ + H I + I+
Sbjct: 1539 RN-GQSTTFECQITGTPKIRVSWYLDGNEITA-------IQKHGISFIDGLATFQISGAR 1590
Query: 429 TSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL-TVTNVTHSTVTLE 477
+ G+Y C ARN+ G ++ +++L V P + L V V +S V LE
Sbjct: 1591 VENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELE 1640
Score = 72.9 bits (171), Expect = 4e-12
Identities = 95/392 (24%), Positives = 158/392 (40%), Gaps = 34/392 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V+ P F + + + E + + G+P I TW K+ +++S+ +
Sbjct: 396 VTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPV-IQVTWFKNNKELSESN--TVRMY 452
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG-IKSVSQ-NVVANPN 275
++ ++L++T + D+G Y+CEAVN G+ + + + P IK++ ++V N
Sbjct: 453 FVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTN 512
Query: 276 EDAVLSCTAIGNPLLAEHIKW--ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
A+L C G I W ++K + K F K+L L I S ++G ++
Sbjct: 513 --ALLQCEVSGTGPF--EISWFKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYE 567
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSF 389
CVV N +G L+ + P FVK ++ GQ L + S
Sbjct: 568 CVVANEVGKCGCMATHLLKE-------PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISV 620
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
TW K G ++ + K F +VL+I +V S G Y C A NE G T+
Sbjct: 621 TWMK-GQEV-IREDGKIKMSFSNG-----VAVLIIPDVQISFGGKYTCLAENEAGSQTSV 673
Query: 450 VKLDVTSAPDQVVSLTVTNVT-HSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV 507
+L V + + VT TLE+ V G WY+ V Y+
Sbjct: 674 GELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFK 733
Query: 508 LPKHATNFTVHGLEKNTDYIFSVMAINKIGQS 539
F L + Y F + N++G S
Sbjct: 734 NNVAQLKFYSAELHDSGQYTFEIS--NEVGSS 763
Score = 72.1 bits (169), Expect = 7e-12
Identities = 73/277 (26%), Positives = 115/277 (41%), Gaps = 23/277 (8%)
Query: 187 RADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSM-LNMTKLTRHDAGIYTCEAVNS 245
+ G+ P I+ W KDG I S S+ + E S+ L + L D YTC+ N
Sbjct: 1924 KVSGSLP-ISAQWFKDGKEI---STSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNV 1979
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP 305
G + ++V P A P+ G P IKW + ++
Sbjct: 1980 AGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFK--IKWFKDDVELVS 2037
Query: 306 KSVTFEP-KNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV---KFKPEMDTS 361
F + TS+L + + G + C V N +GS + ++L+ KF +++ S
Sbjct: 2038 GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEAS 2097
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
VK+ G RL CK P W +N +LP S KY F I +V
Sbjct: 2098 -KIVKA----GDSSRLECKIAGSPEIRVVWFRNEHELP--ASDKYRMTF-----IDSVAV 2145
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ +NN++T D G + C A+N G ++ + K+ V P
Sbjct: 2146 IQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 2182
Score = 70.9 bits (166), Expect = 2e-11
Identities = 71/292 (24%), Positives = 123/292 (42%), Gaps = 20/292 (6%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G P I TW KD I + ++ + L + K+ + DAG YTC A N G
Sbjct: 3902 GTAP-IKITWAKDNREIRPGG--NYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKD 3958
Query: 250 VANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSV 308
+ + V P IK + + + +E C G+P + + W + +I +S
Sbjct: 3959 SCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEI--KVLWYKDETEIQ-ESS 4015
Query: 309 TFEPKNLTSYLII--RKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
F + S ++ E+ G++ C +N GSA+ L VK P P+ ++
Sbjct: 4016 KFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSAS-SSTSLKVKEPPIFRKKPHPIE 4074
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
+ G L C+ + P +W K+ K + + KY + + +T +L N
Sbjct: 4075 TLK--GADVHLECELQGTPPFHVSWYKD--KRELRSGKKY--KIMSENFLTSIHIL---N 4125
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLT-VTNVTHSTVTLE 477
V +D G Y+C A N++G T + + + P V L+ ++ V V L+
Sbjct: 4126 VDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQ 4177
Score = 68.1 bits (159), Expect = 1e-10
Identities = 71/284 (25%), Positives = 113/284 (39%), Gaps = 18/284 (6%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP F N + N + + G+ P + +W KDG I S +
Sbjct: 777 APFFTKPLR-NVDSVVNGTCRLDCKIAGSLP-MRVSWFKDGKEIAASDRY--RIAFVEGT 832
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
+ L + ++ +DAG +TC A NS G+ ++ ++ V P + + P L
Sbjct: 833 ASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKS 892
Query: 283 TAIGNPLLAEHIKWERKGYK--IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
T G+ L I+W KG K + S + L S L + K+ + G + C V+N +
Sbjct: 893 TFQGSTPLT--IRWF-KGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSN-V 948
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV 400
+ L VK +P G +L CK P TW N + +
Sbjct: 949 AGGVECSANLFVK-EPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDRE--I 1005
Query: 401 NTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
S+K H+ + T+VL + +V D G Y C A+NE G
Sbjct: 1006 KESSK-----HRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 1044
Score = 67.7 bits (158), Expect = 2e-10
Identities = 85/390 (21%), Positives = 154/390 (39%), Gaps = 29/390 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V+ P F + V + E + + + G+P I +W ++ + +S N
Sbjct: 3023 LSVKEPPKFVKKLEASKVAKQGESIQLECKISGSP-EIKVSWFRNDSELHESW--KYNMS 3079
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
I+ ++L + + + D+G Y CEA N G A + +++V P V A D
Sbjct: 3080 FINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSD 3139
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
+L C G P + W + ++ + K K+ + L I ++ ++G + C
Sbjct: 3140 VILQCEISGTPPF--EVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKA 3197
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWS 392
N +GS T VKFK P FVK S+ +G L + S W
Sbjct: 3198 TNEVGSDT---CSCSVKFK----EPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWL 3250
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ ++ + S F N + L + + S+ G Y C +N+ G + L
Sbjct: 3251 KDRGEV-IRESENTRISFIDN-----IATLQLGSPEASNSGKYICQIKNDAGMRECSAVL 3304
Query: 453 DVTSAPDQVVSL--TVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLP 509
V P +++ +T T + LE V G W++ R++ DS K+
Sbjct: 3305 TVLE-PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFK-DGRELSADS-KHHITFI 3361
Query: 510 KHATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ + E + ++S N +G+S
Sbjct: 3362 NKVASLKIPCAEMSDKGLYSFEVKNSVGKS 3391
Score = 64.5 bits (150), Expect = 1e-09
Identities = 69/307 (22%), Positives = 117/307 (38%), Gaps = 17/307 (5%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ ++ P F + TV + EP + +G P I W K+ + + S +
Sbjct: 2269 VKLKEPPRFVSKLNSLTV-VAGEPAELQASIEGAQP-IFVQWLKEKEEVIRESENI-RIT 2325
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
+ + L K +AG Y C+ N G ++ V PA I + + E
Sbjct: 2326 FVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGET 2385
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
L C G P L+ ++W + G + + F N S L I + ++ G + V
Sbjct: 2386 CTLECKVAGTPELS--VEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQV 2443
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMC--KCKSVPAPSFTWSKN 394
N +G ++ V+ + + P+F + N G V C +CK + + +
Sbjct: 2444 QNNVGKSSCTAVVDV----SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWF 2499
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
K + + KY F N L +N++ +SD G+Y C A N G L V
Sbjct: 2500 HEKTKIVSGAKYQTTFSDN-----VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV 2554
Query: 455 TSAPDQV 461
P V
Sbjct: 2555 QEPPSFV 2561
Score = 63.7 bits (148), Expect = 3e-09
Identities = 70/292 (23%), Positives = 112/292 (38%), Gaps = 25/292 (8%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ VQ P F+ T V + L + G PP W K + S N
Sbjct: 3493 LTVQEPPSFEQTPDSVEV-LPGMSLTFTSVIRGTPP-FKVKWFKGSRELVPGE--SCNIS 3548
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
+ + L + ++ ++G Y+C N G+A + V PA +
Sbjct: 3549 LEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSP 3608
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPK---SVTFEPKNLTSYLIIRKAKSENLGNFQC 334
VL T G P ++ + W + Y I S+T K ++ L I ++ E+ + C
Sbjct: 3609 IVLEATYTGTPPIS--VSWIKDEYLISQSERCSITMTEK--STILEILESTIEDYAQYSC 3664
Query: 335 VVNNGIGSATKQDV--MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWS 392
++ N G QD+ L+ +P P + +G+ L CK P +W
Sbjct: 3665 LIENEAG----QDICEALVSVLEPPYFIEP-LEHVEAVIGEPATLQCKVDGTPEIRISWY 3719
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
K KL ++ Y +F N + L+IN V SD G Y C A N +G
Sbjct: 3720 KEHTKL--RSAPAYKMQFKNN-----VASLVINKVDHSDVGEYSCKADNSVG 3764
Score = 62.5 bits (145), Expect = 6e-09
Identities = 67/319 (21%), Positives = 127/319 (39%), Gaps = 23/319 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V P F + + + EP + + DG P I +W K+ + S + +
Sbjct: 3679 VSVLEPPYFIEPLEH-VEAVIGEPATLQCKVDGTP-EIRISWYKEHTKLR--SAPAYKMQ 3734
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH---YPAGIKSVSQNVVANP 274
+ + L + K+ D G Y+C+A NS GA ++ + + P ++V
Sbjct: 3735 FKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETL 3794
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGY--KIDPKSVTFEPKNLTSYLIIRKAKSENLGNF 332
C G+ L + W + G K D T N+ + I++ +S ++G +
Sbjct: 3795 GFPVAFECRINGSEPL--QVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQS-HIGQY 3851
Query: 333 QCVVNNGIGSATKQDVMLIVKFK--PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
C +N +G+A+ +++ + + P D P V A +G+ G C T
Sbjct: 3852 NCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLA--LGESGTFKCHVTGTAPIKIT 3909
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
W+K+ ++ + +K + T+ L + V D G Y C A N G + +
Sbjct: 3910 WAKDNREIRPGGN-------YKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSA 3962
Query: 451 KLDVTSAPDQVVSLTVTNV 469
+L V P + L + +
Sbjct: 3963 QLGVQEPPRFIKKLEPSRI 3981
Score = 60.5 bits (140), Expect = 2e-08
Identities = 78/364 (21%), Positives = 137/364 (37%), Gaps = 30/364 (8%)
Query: 182 LIISVRADGNPPSITYTWTKDGLPITQSS--YSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
+++ R G+ P I+ W +DG I SS ++ + + LN++ L D GIYT
Sbjct: 3423 VVLECRVSGSAP-ISVGWFQDGNEIVSGPKCQSSFSENVCT----LNLSLLEPSDTGIYT 3477
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N G+ + ++V P + +V P + G P +KW +
Sbjct: 3478 CVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPF--KVKWFKG 3535
Query: 300 GYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
++ P +S ++ + L + + + G++ C+V N GSA+ + + K
Sbjct: 3536 SRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV---KEPA 3592
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
+ G L P S +W K+ +Y + IT
Sbjct: 3593 TFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKD----------EYLISQSERCSITM 3642
Query: 419 T---SVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLT-VTNVTHSTV 474
T ++L I DY Y C NE G + V P + L V V
Sbjct: 3643 TEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPA 3702
Query: 475 TLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAI 533
TL+ V G SWY+ + +YK + + + ++ ++ + +S A
Sbjct: 3703 TLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQ--FKNNVASLVINKVDHSDVGEYSCKAD 3760
Query: 534 NKIG 537
N +G
Sbjct: 3761 NSVG 3764
Score = 59.3 bits (137), Expect = 6e-08
Identities = 54/226 (23%), Positives = 92/226 (40%), Gaps = 15/226 (6%)
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG-IKSVSQNVVANPNEDAVLSCT 283
L + + +G YTC N+ G A + V PA +K +S + V P + +L T
Sbjct: 2615 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSV-EPGKSIILEST 2673
Query: 284 AIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
G L + W++ G+ I + T L I + + G + C + N G
Sbjct: 2674 YTGT--LPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGR 2731
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
++ ++ P T +++A VG L C+ P + +W K KL
Sbjct: 2732 DVCGALVSTLE-PPYFVTELEPLEAA--VGDSVSLQCQVAGTPEITVSWYKGDTKL--RP 2786
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTT 448
+ +Y F N + L+ N V +D G Y C A N +G +++
Sbjct: 2787 TPEYRTYFTNN-----VATLVFNKVNINDSGEYTCKAENSIGTASS 2827
Score = 59.3 bits (137), Expect = 6e-08
Identities = 80/358 (22%), Positives = 139/358 (38%), Gaps = 24/358 (6%)
Query: 190 GNPPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGA 248
G PP +W KD + Y ++ ++ +LN+ D G Y C+A N G+
Sbjct: 4089 GTPP-FHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA---DIGEYQCKATNDVGS 4144
Query: 249 AVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKS 307
S+++ P ++ ++ L T G ++ + ++ KG + + +
Sbjct: 4145 DTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISV-VWFKDKGEIVRESDN 4203
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKS 367
+ + L + + N G + C + N G + +++ ++ P +K
Sbjct: 4204 IWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVE-KPESIKV 4262
Query: 368 ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNV 427
+ G L C P S W K+G +L + KY F S L I NV
Sbjct: 4263 TT--GDTCTLECTVAGTPELSTKWFKDGKEL--TSDNKYKISFFNK-----VSGLKIINV 4313
Query: 428 ATSDYGSYECGARNELGFSTTTVKLDV---TSAPDQVVSLTVTN-VTHSTVTLEW-VPGF 482
A SD G Y +N +G + T L V T P L TN ++ S+V +E V G
Sbjct: 4314 APSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGS 4373
Query: 483 DGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
SW+ KY+ L + TV+ LE++ ++ +A N G +
Sbjct: 4374 PPISVSWF--HEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDE 4429
Score = 56.8 bits (131), Expect = 3e-07
Identities = 73/329 (22%), Positives = 129/329 (39%), Gaps = 30/329 (9%)
Query: 184 ISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAV 243
++ + G PP I TW + I +SS + + ++L +T + D+G Y CEA
Sbjct: 984 LACKVTGTPP-IKITWFANDREIKESSKHRMS--FVESTAVLRLTDVGIEDSGEYMCEAQ 1040
Query: 244 NSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG--Y 301
N G+ + V V + + D +L G P I W +
Sbjct: 1041 NEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPF--EITWFKDNTIL 1098
Query: 302 KIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
+ K TF +L S L I K + + G +QC V N +GS+ I + +
Sbjct: 1099 RSGRKYKTFIQDHLVS-LQILKFVAADAGEYQCRVTNEVGSS-------ICSARVTLREP 1150
Query: 362 PNFVK---SASNV-GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
P+F+K S S++ G K + TW K+ ++ + + + F N
Sbjct: 1151 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIR--MTFENN---- 1204
Query: 418 YTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV---TSAPDQVVSLTVTNVTHSTV 474
+ L ++ + G Y C A+N+ G + L V + ++ VS+ VT +T+
Sbjct: 1205 -VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATL 1263
Query: 475 TLEWVPGFDGGLQSWYRIRYRKVFDDSYK 503
+++ G W++ YK
Sbjct: 1264 QVKF-SGTKEITAKWFKDGQELTLGSKYK 1291
Score = 56.4 bits (130), Expect = 4e-07
Identities = 71/329 (21%), Positives = 123/329 (37%), Gaps = 26/329 (7%)
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
I +++ M L+ D+G + CEA N G+ + V V P S V N +
Sbjct: 2140 IDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEV 2199
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C G P E + ++ K K KN + + I + ++G + C N
Sbjct: 2200 SLECELSGTPPF-EVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 2258
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKN 394
+GS T + VK K P FV +++ G+ L + W K
Sbjct: 2259 EVGSDT---CVCTVKLK----EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKE 2311
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF---STTTVK 451
++ + S F +N + L ++ G Y C +N+ G T +
Sbjct: 2312 KEEV-IRESENIRITFVEN-----VATLQFAKAEPANAGKYICQIKNDGGMRENMATLMV 2365
Query: 452 LDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPK 510
L+ ++ +TVT T TLE V G WY + K+ S K++
Sbjct: 2366 LEPAVIVEKAGPMTVT--VGETCTLECKVAGTPELSVEWY--KDGKLLTSSQKHKFSFYN 2421
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQS 539
++ + +E+ ++ N +G+S
Sbjct: 2422 KISSLRILSVERQDAGTYTFQVQNNVGKS 2450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 76/338 (22%), Positives = 125/338 (36%), Gaps = 23/338 (6%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G PP TW K+ I S + DR+ L++TK D G Y C N G+
Sbjct: 1645 GTPP-FEVTWLKNNREIRSSKKYTLTDRVSVFN--LHITKCDPSDTGEYQCIVSNEGGSC 1701
Query: 250 VANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID-PKSV 308
+ V++ P +N A T G+P ++ I W + +D +V
Sbjct: 1702 SCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPIS--ITWLKDDQILDEDDNV 1759
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSA 368
+ + L IR + + G + C N G + L+V+ ++ V
Sbjct: 1760 YISFVDSVATLQIRSVDNGHSGRYTCQAKNESG-VERCYAFLLVQEPAQIVEKAKSVDVT 1818
Query: 369 SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVA 428
L C P W K+G ++ ++YF+ +N+ ++ I +V
Sbjct: 1819 EKDPMT--LECVVAGTPELKVKWLKDGKQI---VPSRYFSMSFENNVASFR----IQSVM 1869
Query: 429 TSDYGSYECGARNELGFSTTTV---KLDVTSAPDQVVSLT-VTNVTHSTVTLEW-VPGFD 483
D G Y N+ G S+ LD P LT + V S++ +E V G
Sbjct: 1870 KQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSL 1929
Query: 484 GGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLE 521
W+ + K S KY V + + + V+ LE
Sbjct: 1930 PISAQWF--KDGKEISTSAKYRLVCHERSVSLEVNNLE 1965
Score = 54.0 bits (124), Expect = 2e-06
Identities = 73/346 (21%), Positives = 126/346 (36%), Gaps = 26/346 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P IT +W K + + + + L K+ +D+G YTC+A NS G A +
Sbjct: 2771 PEITVSWYKGDTKLRPTP--EYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSK 2828
Query: 253 ISVSVH---YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSV 308
+ P +++ L+C G+ + + W R G + D +++
Sbjct: 2829 TVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPI--QVCWYRDGVLLRDHENL 2886
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI--VKFKPEMDTSPNFVK 366
+ + L I + + G + C +N +G+A+ + K P D P +
Sbjct: 2887 QTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSID 2946
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
+ G+ C TWSK+ + + Y N T L I
Sbjct: 2947 VIA--GESADFECHVTGAQPMRITWSKDNKE--IRPGGNYTITCVGN-----TPHLRILK 2997
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGL 486
V D G Y C A N++G + +L V P V L + V +++ G
Sbjct: 2998 VGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSP 3057
Query: 487 Q---SWYRIRYRKVFDDSYKYEDVLPKHATNFTVH--GLEKNTDYI 527
+ SW+ R +S+KY T++ E + DYI
Sbjct: 3058 EIKVSWF--RNDSELHESWKYNMSFINSVALLTINEASAEDSGDYI 3101
Score = 52.4 bits (120), Expect = 6e-06
Identities = 80/390 (20%), Positives = 146/390 (37%), Gaps = 30/390 (7%)
Query: 160 VQNAPIFDDTTSYNTVGIENE-PLIISVRADGNPPSITYTWTKDGLPITQS-SYSSG-ND 216
V+ +P F T + + + E +++ G PP TW KD + Y + D
Sbjct: 1054 VKESPYF--TKEFKPIEVLKEYDVMLLAEVAGTPP-FEITWFKDNTILRSGRKYKTFIQD 1110
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNE 276
++S L + K DAG Y C N G+++ + V++ P ++ +
Sbjct: 1111 HLVS----LQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGG 1166
Query: 277 DAVLSCTAIGN-PLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
A T G+ P+ +K + + D +TFE + YL + K + G + C
Sbjct: 1167 TAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHD--GKYVCQ 1224
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N G Q ++ K + V G L K + W K+G
Sbjct: 1225 AKNDAGI---QRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDG 1281
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVK---L 452
+L + +KY + D + S+L I + D G Y +N++G S+ + L
Sbjct: 1282 QELTL--GSKY--KISVTDTV---SILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVL 1334
Query: 453 DVTSAPDQVVSL-TVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK 510
D+ P L + ++ S + LE + + W++ + YK+
Sbjct: 1335 DLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFS--FHD 1392
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + LE ++ A NK G ++
Sbjct: 1393 NTAFLEISQLEGTDSGTYTCSATNKAGHNQ 1422
Score = 52.4 bits (120), Expect = 6e-06
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 13/171 (7%)
Query: 5 KDSGIFKCMINSPSDPPSA---------PMITGYVPGTTLAAGTVQKLACISTGGNPLAT 55
+D+G + C I + S S P + ++ G L C G P
Sbjct: 4598 EDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQC-QLAGTPEIG 4656
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTD--NQAQYRCEATNSATEIPLFETVTLN 113
++W+K D K+ TT + +++ N D + +Y C+A NS E+ +T+
Sbjct: 4657 VSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ 4716
Query: 114 VHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAP 164
P + + G+ C + S + P ++SW++DG P++++P
Sbjct: 4717 EQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSP 4766
Score = 52.0 bits (119), Expect = 8e-06
Identities = 45/152 (29%), Positives = 70/152 (46%), Gaps = 8/152 (5%)
Query: 7 SGIFKCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIH 66
+G +C N P A + P L G +LAC TG P+ +TWF ND++I
Sbjct: 949 AGGVECSANLFVKEP-ATFVEKLEPSQLLKKGDATQLACKVTGTPPIK-ITWFANDREIK 1006
Query: 67 STTKTTDKAV-SAEISILTNV-TDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVR 124
++K V S + LT+V ++ +Y CEA N A V V +P K
Sbjct: 1007 ESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI--VKESPYFTKEF 1064
Query: 125 AEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
+VLK + L+ + A + PP ++W++D
Sbjct: 1065 KPIEVLKE-YDVMLLAEVAGT-PPFEITWFKD 1094
Score = 50.8 bits (116), Expect = 2e-05
Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 9/140 (6%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSA 78
+PPS + P + G +L C G+P+ +TWFKN+K++ + V++
Sbjct: 400 EPPS--FVKKVDPSYLMLPGESARLHC-KLKGSPVIQVTWFKNNKELSESNTVRMYFVNS 456
Query: 79 E-ISILTNV-TDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEA 136
E I +T+V ++ Y CEA N + + P +K D+++ G A
Sbjct: 457 EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE--PPSFIKTLEPADIVR-GTNA 513
Query: 137 TLICDSASSNPPATLSWWRD 156
L C+ S P +SW++D
Sbjct: 514 LLQCE-VSGTGPFEISWFKD 532
Score = 50.0 bits (114), Expect = 3e-05
Identities = 70/291 (24%), Positives = 116/291 (39%), Gaps = 21/291 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P ++ W KDG + S+ S + I++ + L + D G+Y+ E NS G +
Sbjct: 3337 PELSAKWFKDGREL--SADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 3394
Query: 253 ISVSVH---YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI--DPKS 307
+SV V P ++V A VL C G+ ++ + W + G +I PK
Sbjct: 3395 VSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPIS--VGWFQDGNEIVSGPKC 3452
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKS 367
+ +N+ + L + + + G + CV N GS + +L V+ P + +P+ V+
Sbjct: 3453 QSSFSENVCT-LNLSLLEPSDTGIYTCVAANVAGS-DECSAVLTVQEPPSFEQTPDSVEV 3510
Query: 368 ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNV 427
G + P W K +L S E D +T L + V
Sbjct: 3511 LP--GMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLE----DFVT---ELELFEV 3561
Query: 428 ATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNV-THSTVTLE 477
+ G Y C N+ G ++ T L V V L +V T S + LE
Sbjct: 3562 QPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLE 3612
Score = 49.2 bits (112), Expect = 6e-05
Identities = 55/216 (25%), Positives = 83/216 (38%), Gaps = 27/216 (12%)
Query: 259 YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSY 318
YP I + Q+ V + + A C G L + W K KI P + +Y
Sbjct: 8 YPPAIITPLQDTVTSEGQPARFQCRVSGTDL---KVSWYSKDKKIKPSRFFRMTQFEDTY 64
Query: 319 -LIIRKAKSENLGNFQCVVNNGIGSATK---------QDVM---LIVKFKPEMDTSPNFV 365
L I +A E+ G + V NN +G + + ++ + + + EM +P
Sbjct: 65 QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIK 124
Query: 366 KSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
+ + G + + C+ +S P F W K G + + S K K Y S
Sbjct: 125 RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE--IYESDKCSIRSSK-----YISS 177
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
L I D G Y C A NE G + T L VT A
Sbjct: 178 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA 213
Score = 48.4 bits (110), Expect = 1e-04
Identities = 59/298 (19%), Positives = 108/298 (36%), Gaps = 16/298 (5%)
Query: 174 TVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRH 233
T G+ +++ + G+PP I+ +W +G I SS + L + L
Sbjct: 4356 TNGLSGSSVVMECKVYGSPP-ISVSWFHEGNEI--SSGRKYQTTLTDNTCALTVNMLEES 4412
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D+G YTC A N G+ + ++V P + + + G P +
Sbjct: 4413 DSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFS-- 4470
Query: 294 IKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W + ++ P ++ + L + + G + C+V+N G A+ L +
Sbjct: 4471 VSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKAS-CTTHLYI 4529
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
K + N + G+ L P S TW KNG +N +
Sbjct: 4530 KAPAKFVKRLN--DYSIEKGKPLILEGTFTGTPPISVTWKKNG----INVTPSQRCNITT 4583
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
+ + +L I + D G Y C N G + + ++ + P V L V+
Sbjct: 4584 TEK---SPILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVS 4638
Score = 47.6 bits (108), Expect = 2e-04
Identities = 70/324 (21%), Positives = 115/324 (35%), Gaps = 22/324 (6%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS--YSSGNDRIISEGSMLNMTKL 230
NT G+ I+ + G+ P I+ W + I + ++ +D + + L + L
Sbjct: 2473 NTGGVLGASCILECKVAGSSP-ISVAWFHEKTKIVSGAKYQTTFSDNVCT----LQLNSL 2527
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGN-PL 289
D G YTC A N G+ ++V P + + P ++ + G P
Sbjct: 2528 DSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPF 2587
Query: 290 LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM 349
+ R+ K D ++ FE + + L + G + CVV+N G A+ +
Sbjct: 2588 KVNWFRGARELVKGDRCNIYFE--DTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRL 2645
Query: 350 LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
+ K + G+ L S TW K+G + TS K
Sbjct: 2646 FV---KEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFN--ITTSEKCNIV 2700
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL-TVTN 468
+ T +L I N D G Y C NE G + P V L +
Sbjct: 2701 TTEK-----TCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEA 2755
Query: 469 VTHSTVTLE-WVPGFDGGLQSWYR 491
+V+L+ V G SWY+
Sbjct: 2756 AVGDSVSLQCQVAGTPEITVSWYK 2779
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 7/133 (5%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVS--AEISILTNVTDNQAQYRCEATN 99
+L C G+P ++WF+ND ++H + K ++ A ++I ++ Y CEA N
Sbjct: 3048 QLEC-KISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHN 3106
Query: 100 SATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIP 159
+ +T+ AP + P G + L C+ S PP + W +D
Sbjct: 3107 GVGDASCSTALTVK---APPVFTQKPSPVGALKGSDVILQCE-ISGTPPFEVVWVKDRKQ 3162
Query: 160 VQNAPIFDDTTSY 172
V+N+ F T+ +
Sbjct: 3163 VRNSKKFKITSKH 3175
Score = 44.0 bits (99), Expect = 0.002
Identities = 40/169 (23%), Positives = 71/169 (42%), Gaps = 7/169 (4%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSA 78
+AP+I + +A G + K C P WFK ++I+ + K + K +S+
Sbjct: 119 AAPVIKRKIEPLEVALGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 177
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATL 138
+ T V D +Y C+A+N + T+T+ + P + R + G A
Sbjct: 178 LEILRTQVVDC-GEYTCKASNEYGSVSCTATLTVTEAYPPTFLS-RPKSLTTFVGKAAKF 235
Query: 139 ICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVR 187
IC + + P W +DG + +P + + + N +E L I R
Sbjct: 236 IC-TVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDR 283
Score = 42.7 bits (96), Expect = 0.005
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 9/113 (7%)
Query: 49 GGNPLATLTWFKNDKKIHSTTKTT----DKAVSAEISILTNVTDNQAQYRCEATNSATEI 104
GG T+ WFK++K++HS + D + S E+ TD+ Y C+ +N
Sbjct: 1457 GGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLEL-FAAKATDS-GTYICQLSNDVGTA 1514
Query: 105 PLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG 157
TL V P+ +K + VL+ G T C + P +SW+ DG
Sbjct: 1515 T--SKATLFVKEPPQFIKKPSPVLVLRNGQSTTFEC-QITGTPKIRVSWYLDG 1564
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 4/125 (3%)
Query: 36 AAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVT--DNQAQY 93
A G L C G P T++W+K D K+ T + + +++ N ++ +Y
Sbjct: 2756 AVGDSVSLQC-QVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEY 2814
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSW 153
C+A NS + P + + + G+ TL C + + P + W
Sbjct: 2815 TCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTC-RLNGSAPIQVCW 2873
Query: 154 WRDGI 158
+RDG+
Sbjct: 2874 YRDGV 2878
Score = 40.7 bits (91), Expect = 0.021
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 49 GGNPLATLTWFKNDKKIHSTTKTTDKAV-SAEISILTNVT-DNQAQYRCEATNSATEIPL 106
GG+P + W+K++ +I ++K V S + + N++ ++ Y CEA N+A
Sbjct: 3995 GGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSAS- 4053
Query: 107 FETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
+ +L V P + + P G + L C+ PP +SW++D
Sbjct: 4054 -SSTSLKVK-EPPIFRKKPHPIETLKGADVHLECE-LQGTPPFHVSWYKD 4100
Score = 40.7 bits (91), Expect = 0.021
Identities = 34/156 (21%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 45 CISTGGNPLATLTWFKNDKKIHSTTKTTDKAV--SAEISILTNVTDNQAQYRCEATNSAT 102
C TG P+ ++W K+ ++I S K + SA +++L + QY C A N
Sbjct: 4839 CHVTGTQPIK-VSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVG 4897
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQN 162
+ + + P + R V + + + + + P T++W+++ I +Q
Sbjct: 4898 KDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQ- 4956
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYT 198
TS + +N L++ VR G + YT
Sbjct: 4957 ------PTSNCEITFKNNTLVLQVRKAGMNDAGLYT 4986
Score = 40.3 bits (90), Expect = 0.028
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 13/158 (8%)
Query: 3 SKKDSGIFKCMIN-SPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKN 61
++ D+G C I +PP+ I P + V+ L C TG P +TW KN
Sbjct: 1601 ARNDAGTASCSIELKVKEPPT--FIRELKPVEVVKYSDVE-LECEVTGTPPFE-VTWLKN 1656
Query: 62 DKKIHSTTK--TTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPE 119
+++I S+ K TD+ + I + +Y+C +N V L P
Sbjct: 1657 NREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE--PPS 1714
Query: 120 AV-KVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
+ K+ VLK + + + +PP +++W +D
Sbjct: 1715 FIKKIENTTTVLK---SSATFQSTVAGSPPISITWLKD 1749
Score = 39.1 bits (87), Expect = 0.064
Identities = 37/123 (30%), Positives = 53/123 (43%), Gaps = 11/123 (8%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT----DKAVSAEISILTNVTDNQAQY 93
G+ L CI G +P++ + WFK+D++I ++ K D EIS L TD+ Y
Sbjct: 1354 GSFIDLECIVAGSHPIS-IQWFKDDQEISASEKYKFSFHDNTAFLEISQLEG-TDS-GTY 1410
Query: 94 RCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSW 153
C ATN A + L V P V+ DV P L P T+ W
Sbjct: 1411 TCSATNKAGHNQC--SGHLTVKEPPYFVEKPQSQDV-NPNTRVQLKA-LVGGTAPMTIKW 1466
Query: 154 WRD 156
++D
Sbjct: 1467 FKD 1469
Score = 37.5 bits (83), Expect = 0.19
Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 8/173 (4%)
Query: 4 KKDSGIFKCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDK 63
K D+G+ +C P A +I P T+ G L C+ TG P + WFK+ +
Sbjct: 3292 KNDAGMRECSAVLTVLEP-ARIIEKPEP-MTVTTGNPFALECVVTG-TPELSAKWFKDGR 3348
Query: 64 KIHSTTKTTDKAVS--AEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAV 121
++ + +K ++ A + I ++ Y E NS + +V ++ P +
Sbjct: 3349 ELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSF 3408
Query: 122 KVRAEPDVLKP-GIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYN 173
+R DV G L C S + P ++ W++DG + + P + S N
Sbjct: 3409 -IRKLKDVNAILGASVVLEC-RVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN 3459
Score = 36.3 bits (80), Expect = 0.45
Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 7/122 (5%)
Query: 37 AGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTN--VTDNQAQYR 94
AG +L C G+P + WF+N+ ++ ++ K + + I N T++ +
Sbjct: 2102 AGDSSRLEC-KIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFI 2160
Query: 95 CEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWW 154
CEA N A V V P + LK E +L C+ S PP + W+
Sbjct: 2161 CEAQNPAGSTSCSTKVI--VKEPPVFSSFPPIVETLK-NAEVSLECE-LSGTPPFEVVWY 2216
Query: 155 RD 156
+D
Sbjct: 2217 KD 2218
Score = 35.5 bits (78), Expect = 0.79
Identities = 33/176 (18%), Positives = 66/176 (37%), Gaps = 6/176 (3%)
Query: 4 KKDSGIFKCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDK 63
K D+G+ +C P+ I + G L C + G P + WFK+ K
Sbjct: 4233 KNDAGMQECFATLSVLEPAT--IVEKPESIKVTTGDTCTLEC-TVAGTPELSTKWFKDGK 4289
Query: 64 KIHSTTKTTDKAVS--AEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAV 121
++ S K + + + I+ + Y E N + ++ ++ P +
Sbjct: 4290 ELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSF 4349
Query: 122 KVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGI 177
+ + G + C S PP ++SW+ +G + + + T + NT +
Sbjct: 4350 TRKLKETNGLSGSSVVMECKVYGS-PPISVSWFHEGNEISSGRKYQTTLTDNTCAL 4404
Score = 35.5 bits (78), Expect = 0.79
Identities = 34/150 (22%), Positives = 59/150 (39%), Gaps = 11/150 (7%)
Query: 383 SVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNE 442
SVP W +NG L K E HK +T I +V D G Y C +
Sbjct: 5434 SVPNVKSEWFRNGRILKPQGRHKTEVE-HKVHKLT------IADVRAEDQGQYTCKYEDL 5486
Query: 443 LGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSY 502
+ ++ + ++ ++ V+ H + T E FD + +WY + +S
Sbjct: 5487 ETSAELRIEAEPIQFTKRIQNIVVSE--HQSATFECEVSFDDAIVTWY--KGPTELTESQ 5542
Query: 503 KYEDVLPKHATNFTVHGLEKNTDYIFSVMA 532
KY T+H + + + ++SV+A
Sbjct: 5543 KYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 5572
Score = 33.1 bits (72), Expect = 4.2
Identities = 28/109 (25%), Positives = 44/109 (40%), Gaps = 6/109 (5%)
Query: 50 GNPLATLTWFKNDKKIHS--TTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLF 107
G P +TWFK++ + S KT + + IL V + +Y+C TN
Sbjct: 1083 GTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICS 1142
Query: 108 ETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
VTL P +K L+ G A + + P T++W +D
Sbjct: 1143 ARVTLRE--PPSFIKKIESTSSLRGGTAA--FQATLKGSLPITVTWLKD 1187
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 87.4 bits (207), Expect = 2e-16
Identities = 99/388 (25%), Positives = 161/388 (41%), Gaps = 28/388 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V+ AP + D N + E + RA+GNP T W +G P+ QS+ + N
Sbjct: 325 VRVKAAPYWLDEPK-NLILAPGEDGRLVCRANGNPKP-TVQWMVNGEPL-QSAPPNPNRE 381
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--PAGIKSVSQNVVANPN 275
+ + + T+++ +Y C N G +AN VSV P + +Q +
Sbjct: 382 VAGDTIIFRDTQISSR--AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILY 439
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
L C G+P+ ++W + G + + S L I+ + E+ G + CV
Sbjct: 440 NRTRLDCPFFGSPIPT--LRWFKNGQGSNLDGGNYHVYENGS-LEIKMIRKEDQGIYTCV 496
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WSK 393
N +G A Q V L VK + P + G +L C+ K P+ T W K
Sbjct: 497 ATNILGKAENQ-VRLEVKDPTRIYRMPE--DQVARRGTTVQLECRVKHDPSLKLTVSWLK 553
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+ L + K ++D +T I VA D GSY C A EL L
Sbjct: 554 DDEPLYIGNRMK-----KEDDSLT------IFGVAERDQGSYTCVASTELDQDLAKAYLT 602
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSWYRIRYRK-VFDDSYKYEDVLPKH 511
V PD+ L +T++ +V L W+PG + + Y +++ + F ++
Sbjct: 603 VLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPG 662
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ N V L +Y F V+AIN++G S
Sbjct: 663 SVNSAVLRLSPYVNYQFRVIAINEVGSS 690
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/380 (23%), Positives = 149/380 (39%), Gaps = 32/380 (8%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDG--LPITQSSYSSGNDRIISE 221
++ T+ + + + L++ A G P P I W K G LP ++ + + N
Sbjct: 241 MYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKKGGDLPSDKAKFENFN------ 292
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
L +T ++ D+G Y C A N G+ ISV V +N++ P ED L
Sbjct: 293 -KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLV 351
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C A GNP ++W G + + +I R + + +QC +N G
Sbjct: 352 CRANGNP--KPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 409
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
+ ++ P M + N + + RL C P P+ W KNG ++
Sbjct: 410 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT-RLDCPFFGSPIPTLRWFKNGQGSNLD 468
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
N H+ L I + D G Y C A N LG + V+L+V P ++
Sbjct: 469 GG---------NYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD-PTRI 518
Query: 462 VSLTVTNVTH--STVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKY-EDVLPKHATNFTVH 518
+ V +TV LE D L+ + + K DD Y + + K + T+
Sbjct: 519 YRMPEDQVARRGTTVQLECRVKHDPSLK--LTVSWLK--DDEPLYIGNRMKKEDDSLTIF 574
Query: 519 GLEKNTDYIFSVMAINKIGQ 538
G+ + ++ +A ++ Q
Sbjct: 575 GVAERDQGSYTCVASTELDQ 594
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQA-QYRCEATNSA 101
L CI++G P + W+K + S K + + + I TNV++ + +Y C A+N
Sbjct: 260 LECIASGV-PTPDIAWYKKGGDLPSD-KAKFENFNKALRI-TNVSEEDSGEYFCLASNKM 316
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPD--VLKPGIEATLICDSASSNPPATLSWWRDGIP 159
I T+++ V AP + EP +L PG + L+C A+ NP T+ W +G P
Sbjct: 317 GSIR--HTISVRVKAAPYWLD---EPKNLILAPGEDGRLVC-RANGNPKPTVQWMVNGEP 370
Query: 160 VQNAP 164
+Q+AP
Sbjct: 371 LQSAP 375
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 17/202 (8%)
Query: 245 SQGAAVANISVSVHYPAGI-KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI 303
S G A+ I + + P I K +++ + +P ++ ++ C A GNP + H + + I
Sbjct: 20 SLGGAI-EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNI 78
Query: 304 --DPKSVTFEPKNLTSYLIIRKA--KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
DP+ V+ ++ T + R E G +QC N G+A + L V P +
Sbjct: 79 AKDPR-VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP-LW 136
Query: 360 TSPNFVKSASNVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
N G L C +P+P W + ++ P+ T K ++ H D Y
Sbjct: 137 PKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSME-PI-TQDKRVSQGHNGD--LY 192
Query: 419 TSVLLINNVATSDYGSYECGAR 440
S +++ ++ T Y C AR
Sbjct: 193 FSNVMLQDMQT----DYSCNAR 210
Score = 33.9 bits (74), Expect = 2.4
Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQY 93
LA G +L C GNP T+ W N + + S ++ V+ + I + ++A Y
Sbjct: 342 LAPGEDGRLVC-RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVY 400
Query: 94 RCEATN 99
+C +N
Sbjct: 401 QCNTSN 406
Score = 32.7 bits (71), Expect = 5.5
Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 4/112 (3%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P+ TL WFKN + + + + I ++Q Y C ATN +
Sbjct: 450 GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE--NQ 507
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPV 160
V L V P + E V + G L C + T+SW +D P+
Sbjct: 508 VRLEVK-DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL 558
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 87.4 bits (207), Expect = 2e-16
Identities = 99/388 (25%), Positives = 161/388 (41%), Gaps = 28/388 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V+ AP + D N + E + RA+GNP T W +G P+ QS+ + N
Sbjct: 342 VRVKAAPYWLDEPK-NLILAPGEDGRLVCRANGNPKP-TVQWMVNGEPL-QSAPPNPNRE 398
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--PAGIKSVSQNVVANPN 275
+ + + T+++ +Y C N G +AN VSV P + +Q +
Sbjct: 399 VAGDTIIFRDTQISSR--AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILY 456
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
L C G+P+ ++W + G + + S L I+ + E+ G + CV
Sbjct: 457 NRTRLDCPFFGSPIPT--LRWFKNGQGSNLDGGNYHVYENGS-LEIKMIRKEDQGIYTCV 513
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WSK 393
N +G A Q V L VK + P + G +L C+ K P+ T W K
Sbjct: 514 ATNILGKAENQ-VRLEVKDPTRIYRMPE--DQVARRGTTVQLECRVKHDPSLKLTVSWLK 570
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+ L + K ++D +T I VA D GSY C A EL L
Sbjct: 571 DDEPLYIGNRMK-----KEDDSLT------IFGVAERDQGSYTCVASTELDQDLAKAYLT 619
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSWYRIRYRK-VFDDSYKYEDVLPKH 511
V PD+ L +T++ +V L W+PG + + Y +++ + F ++
Sbjct: 620 VLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPG 679
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ N V L +Y F V+AIN++G S
Sbjct: 680 SVNSAVLRLSPYVNYQFRVIAINEVGSS 707
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/380 (23%), Positives = 149/380 (39%), Gaps = 32/380 (8%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDG--LPITQSSYSSGNDRIISE 221
++ T+ + + + L++ A G P P I W K G LP ++ + + N
Sbjct: 258 MYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKKGGDLPSDKAKFENFN------ 309
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
L +T ++ D+G Y C A N G+ ISV V +N++ P ED L
Sbjct: 310 -KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLV 368
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C A GNP ++W G + + +I R + + +QC +N G
Sbjct: 369 CRANGNP--KPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
+ ++ P M + N + + RL C P P+ W KNG ++
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT-RLDCPFFGSPIPTLRWFKNGQGSNLD 485
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
N H+ L I + D G Y C A N LG + V+L+V P ++
Sbjct: 486 GG---------NYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD-PTRI 535
Query: 462 VSLTVTNVTH--STVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKY-EDVLPKHATNFTVH 518
+ V +TV LE D L+ + + K DD Y + + K + T+
Sbjct: 536 YRMPEDQVARRGTTVQLECRVKHDPSLK--LTVSWLK--DDEPLYIGNRMKKEDDSLTIF 591
Query: 519 GLEKNTDYIFSVMAINKIGQ 538
G+ + ++ +A ++ Q
Sbjct: 592 GVAERDQGSYTCVASTELDQ 611
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQA-QYRCEATNSA 101
L CI++G P + W+K + S K + + + I TNV++ + +Y C A+N
Sbjct: 277 LECIASGV-PTPDIAWYKKGGDLPSD-KAKFENFNKALRI-TNVSEEDSGEYFCLASNKM 333
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPD--VLKPGIEATLICDSASSNPPATLSWWRDGIP 159
I T+++ V AP + EP +L PG + L+C A+ NP T+ W +G P
Sbjct: 334 GSIR--HTISVRVKAAPYWLD---EPKNLILAPGEDGRLVC-RANGNPKPTVQWMVNGEP 387
Query: 160 VQNAP 164
+Q+AP
Sbjct: 388 LQSAP 392
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 17/202 (8%)
Query: 245 SQGAAVANISVSVHYPAGI-KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI 303
S G A+ I + + P I K +++ + +P ++ ++ C A GNP + H + + I
Sbjct: 20 SLGGAI-EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNI 78
Query: 304 --DPKSVTFEPKNLTSYLIIRKA--KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
DP+ V+ ++ T + R E G +QC N G+A + L V P +
Sbjct: 79 AKDPR-VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP-LW 136
Query: 360 TSPNFVKSASNVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
N G L C +P+P W + ++ P+ T K ++ H D Y
Sbjct: 137 PKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSME-PI-TQDKRVSQGHNGD--LY 192
Query: 419 TSVLLINNVATSDYGSYECGAR 440
S +++ ++ T Y C AR
Sbjct: 193 FSNVMLQDMQT----DYSCNAR 210
Score = 33.9 bits (74), Expect = 2.4
Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQY 93
LA G +L C GNP T+ W N + + S ++ V+ + I + ++A Y
Sbjct: 359 LAPGEDGRLVC-RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVY 417
Query: 94 RCEATN 99
+C +N
Sbjct: 418 QCNTSN 423
Score = 32.7 bits (71), Expect = 5.5
Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 4/112 (3%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P+ TL WFKN + + + + I ++Q Y C ATN +
Sbjct: 467 GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE--NQ 524
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPV 160
V L V P + E V + G L C + T+SW +D P+
Sbjct: 525 VRLEVK-DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL 575
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 87.4 bits (207), Expect = 2e-16
Identities = 99/388 (25%), Positives = 161/388 (41%), Gaps = 28/388 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V+ AP + D N + E + RA+GNP T W +G P+ QS+ + N
Sbjct: 139 VRVKAAPYWLDEPK-NLILAPGEDGRLVCRANGNPKP-TVQWMVNGEPL-QSAPPNPNRE 195
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--PAGIKSVSQNVVANPN 275
+ + + T+++ +Y C N G +AN VSV P + +Q +
Sbjct: 196 VAGDTIIFRDTQISSR--AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILY 253
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
L C G+P+ ++W + G + + S L I+ + E+ G + CV
Sbjct: 254 NRTRLDCPFFGSPIPT--LRWFKNGQGSNLDGGNYHVYENGS-LEIKMIRKEDQGIYTCV 310
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WSK 393
N +G A Q V L VK + P + G +L C+ K P+ T W K
Sbjct: 311 ATNILGKAENQ-VRLEVKDPTRIYRMPE--DQVARRGTTVQLECRVKHDPSLKLTVSWLK 367
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+ L + K ++D +T I VA D GSY C A EL L
Sbjct: 368 DDEPLYIGNRMK-----KEDDSLT------IFGVAERDQGSYTCVASTELDQDLAKAYLT 416
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSWYRIRYRK-VFDDSYKYEDVLPKH 511
V PD+ L +T++ +V L W+PG + + Y +++ + F ++
Sbjct: 417 VLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPG 476
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ N V L +Y F V+AIN++G S
Sbjct: 477 SVNSAVLRLSPYVNYQFRVIAINEVGSS 504
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/380 (23%), Positives = 149/380 (39%), Gaps = 32/380 (8%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDG--LPITQSSYSSGNDRIISE 221
++ T+ + + + L++ A G P P I W K G LP ++ + + N
Sbjct: 55 MYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKKGGDLPSDKAKFENFN------ 106
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
L +T ++ D+G Y C A N G+ ISV V +N++ P ED L
Sbjct: 107 -KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLV 165
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C A GNP ++W G + + +I R + + +QC +N G
Sbjct: 166 CRANGNP--KPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 223
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
+ ++ P M + N + + RL C P P+ W KNG ++
Sbjct: 224 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT-RLDCPFFGSPIPTLRWFKNGQGSNLD 282
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
N H+ L I + D G Y C A N LG + V+L+V P ++
Sbjct: 283 GG---------NYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD-PTRI 332
Query: 462 VSLTVTNVTH--STVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKY-EDVLPKHATNFTVH 518
+ V +TV LE D L+ + + K DD Y + + K + T+
Sbjct: 333 YRMPEDQVARRGTTVQLECRVKHDPSLK--LTVSWLK--DDEPLYIGNRMKKEDDSLTIF 388
Query: 519 GLEKNTDYIFSVMAINKIGQ 538
G+ + ++ +A ++ Q
Sbjct: 389 GVAERDQGSYTCVASTELDQ 408
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQA-QYRCEATNSA 101
L CI++G P + W+K + S K + + + I TNV++ + +Y C A+N
Sbjct: 74 LECIASGV-PTPDIAWYKKGGDLPSD-KAKFENFNKALRI-TNVSEEDSGEYFCLASNKM 130
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPD--VLKPGIEATLICDSASSNPPATLSWWRDGIP 159
I T+++ V AP + EP +L PG + L+C A+ NP T+ W +G P
Sbjct: 131 GSIR--HTISVRVKAAPYWLD---EPKNLILAPGEDGRLVC-RANGNPKPTVQWMVNGEP 184
Query: 160 VQNAP 164
+Q+AP
Sbjct: 185 LQSAP 189
Score = 33.9 bits (74), Expect = 2.4
Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQY 93
LA G +L C GNP T+ W N + + S ++ V+ + I + ++A Y
Sbjct: 156 LAPGEDGRLVC-RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVY 214
Query: 94 RCEATN 99
+C +N
Sbjct: 215 QCNTSN 220
Score = 32.7 bits (71), Expect = 5.5
Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 4/112 (3%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P+ TL WFKN + + + + I ++Q Y C ATN +
Sbjct: 264 GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE--NQ 321
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPV 160
V L V P + E V + G L C + T+SW +D P+
Sbjct: 322 VRLEVK-DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL 372
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 87.4 bits (207), Expect = 2e-16
Identities = 99/388 (25%), Positives = 161/388 (41%), Gaps = 28/388 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ V+ AP + D N + E + RA+GNP T W +G P+ QS+ + N
Sbjct: 395 VRVKAAPYWLDEPK-NLILAPGEDGRLVCRANGNPKP-TVQWMVNGEPL-QSAPPNPNRE 451
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--PAGIKSVSQNVVANPN 275
+ + + T+++ +Y C N G +AN VSV P + +Q +
Sbjct: 452 VAGDTIIFRDTQISSR--AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILY 509
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
L C G+P+ ++W + G + + S L I+ + E+ G + CV
Sbjct: 510 NRTRLDCPFFGSPIPT--LRWFKNGQGSNLDGGNYHVYENGS-LEIKMIRKEDQGIYTCV 566
Query: 336 VNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WSK 393
N +G A Q V L VK + P + G +L C+ K P+ T W K
Sbjct: 567 ATNILGKAENQ-VRLEVKDPTRIYRMPE--DQVARRGTTVQLECRVKHDPSLKLTVSWLK 623
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
+ L + K ++D +T I VA D GSY C A EL L
Sbjct: 624 DDEPLYIGNRMK-----KEDDSLT------IFGVAERDQGSYTCVASTELDQDLAKAYLT 672
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSWYRIRYRK-VFDDSYKYEDVLPKH 511
V PD+ L +T++ +V L W+PG + + Y +++ + F ++
Sbjct: 673 VLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPG 732
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ N V L +Y F V+AIN++G S
Sbjct: 733 SVNSAVLRLSPYVNYQFRVIAINEVGSS 760
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/380 (23%), Positives = 149/380 (39%), Gaps = 32/380 (8%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDG--LPITQSSYSSGNDRIISE 221
++ T+ + + + L++ A G P P I W K G LP ++ + + N
Sbjct: 311 MYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKKGGDLPSDKAKFENFN------ 362
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
L +T ++ D+G Y C A N G+ ISV V +N++ P ED L
Sbjct: 363 -KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLV 421
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C A GNP ++W G + + +I R + + +QC +N G
Sbjct: 422 CRANGNP--KPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 479
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
+ ++ P M + N + + RL C P P+ W KNG ++
Sbjct: 480 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT-RLDCPFFGSPIPTLRWFKNGQGSNLD 538
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
N H+ L I + D G Y C A N LG + V+L+V P ++
Sbjct: 539 GG---------NYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD-PTRI 588
Query: 462 VSLTVTNVTH--STVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKY-EDVLPKHATNFTVH 518
+ V +TV LE D L+ + + K DD Y + + K + T+
Sbjct: 589 YRMPEDQVARRGTTVQLECRVKHDPSLK--LTVSWLK--DDEPLYIGNRMKKEDDSLTIF 644
Query: 519 GLEKNTDYIFSVMAINKIGQ 538
G+ + ++ +A ++ Q
Sbjct: 645 GVAERDQGSYTCVASTELDQ 664
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQA-QYRCEATNSA 101
L CI++G P + W+K + S K + + + I TNV++ + +Y C A+N
Sbjct: 330 LECIASGV-PTPDIAWYKKGGDLPSD-KAKFENFNKALRI-TNVSEEDSGEYFCLASNKM 386
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPD--VLKPGIEATLICDSASSNPPATLSWWRDGIP 159
I T+++ V AP + EP +L PG + L+C A+ NP T+ W +G P
Sbjct: 387 GSIR--HTISVRVKAAPYWLD---EPKNLILAPGEDGRLVC-RANGNPKPTVQWMVNGEP 440
Query: 160 VQNAP 164
+Q+AP
Sbjct: 441 LQSAP 445
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 17/202 (8%)
Query: 245 SQGAAVANISVSVHYPAGI-KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI 303
S G A+ I + + P I K +++ + +P ++ ++ C A GNP + H + + I
Sbjct: 73 SLGGAI-EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNI 131
Query: 304 --DPKSVTFEPKNLTSYLIIRKA--KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
DP+ V+ ++ T + R E G +QC N G+A + L V P +
Sbjct: 132 AKDPR-VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP-LW 189
Query: 360 TSPNFVKSASNVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
N G L C +P+P W + ++ P+ T K ++ H D Y
Sbjct: 190 PKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSME-PI-TQDKRVSQGHNGD--LY 245
Query: 419 TSVLLINNVATSDYGSYECGAR 440
S +++ ++ T Y C AR
Sbjct: 246 FSNVMLQDMQT----DYSCNAR 263
Score = 33.9 bits (74), Expect = 2.4
Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQY 93
LA G +L C GNP T+ W N + + S ++ V+ + I + ++A Y
Sbjct: 412 LAPGEDGRLVC-RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVY 470
Query: 94 RCEATN 99
+C +N
Sbjct: 471 QCNTSN 476
Score = 32.7 bits (71), Expect = 5.5
Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 4/112 (3%)
Query: 50 GNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFET 109
G+P+ TL WFKN + + + + I ++Q Y C ATN +
Sbjct: 520 GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE--NQ 577
Query: 110 VTLNVHFAPEAVKVRAEPDVLKPGIEATLICD-SASSNPPATLSWWRDGIPV 160
V L V P + E V + G L C + T+SW +D P+
Sbjct: 578 VRLEVK-DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL 628
>U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphatase
sigma protein.
Length = 1948
Score = 87.0 bits (206), Expect = 2e-16
Identities = 95/388 (24%), Positives = 159/388 (40%), Gaps = 44/388 (11%)
Query: 175 VGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRH 233
+G+ +A G+P TW K G + + + + S G++L + L T
Sbjct: 43 IGVSGGVASFVCQATGDPKP-RVTWNKKGKKVNSQRFET-IEFDESAGAVLRIQPLRTPR 100
Query: 234 DAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIG 286
D +Y C A NS G + ++V P+G ++ Q V A + C A G
Sbjct: 101 DENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASG 160
Query: 287 NPLLAEHIKWERKGYKIDP----------KSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
NP I W + +DP +S TFE + L I ++ + G ++CV
Sbjct: 161 NP--DPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVA 218
Query: 337 NNGIGSATKQDVMLIVKFKPEMD-TSPNF--VKSASNVGQVGRLMCKCKSV--PAPSFTW 391
N G L V+ E+ +P F + + + G + C +V P P W
Sbjct: 219 TNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKW 278
Query: 392 SKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVK 451
+ L ++D +VL + +V D +Y C A + LG +
Sbjct: 279 MQGAEDLTP-----------EDDMPVGRNVLELTDV--KDSANYTCVAMSSLGVIEAVAQ 325
Query: 452 LDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYR-KVFDDSYKYEDVLPK 510
+ V S P + VT T +++T+ W G + S+Y I Y+ K D Y+ ++ +
Sbjct: 326 ITVKSLPKAPGTPMVTENTATSITITWDSGNPDPV-SYYVIEYKSKSQDGPYQIKEDIT- 383
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQ 538
T +++ GL N++Y V A+N IGQ
Sbjct: 384 -TTRYSIGGLSPNSEYEIWVSAVNSIGQ 410
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 10/132 (7%)
Query: 37 AGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSAEISILTNVTDNQAQ- 92
+G V C +TG +P +TW K KK++S T D++ A + I T
Sbjct: 46 SGGVASFVCQATG-DPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENV 104
Query: 93 YRCEATNSATEIPLFETVT-LNVHFAPEA---VKVRAEPDVLKPGIEATLICDSASSNPP 148
Y C A NS EI + +T L P + + + V++ AT++C +AS NP
Sbjct: 105 YECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLC-AASGNPD 163
Query: 149 ATLSWWRDGIPV 160
++W++D +PV
Sbjct: 164 PEITWFKDFLPV 175
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 87.0 bits (206), Expect = 2e-16
Identities = 88/370 (23%), Positives = 155/370 (41%), Gaps = 33/370 (8%)
Query: 181 PLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTC 240
PL +A G P TY W K+G+P++ S R+ +L + + + DAG+Y C
Sbjct: 406 PLRWECKATGKPRP-TYRWLKNGVPLSPQS------RVEMVNGVLMIHNVNQSDAGMYQC 458
Query: 241 EAVNSQGAAVANISVSVHYPA---GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
A N GA A+ + + A + + + ++ +++ V+ C G+P I W+
Sbjct: 459 LAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSP--KPTISWK 516
Query: 298 RKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ + + K + P S I+ +KS+ G + C N GSA + L VK
Sbjct: 517 KGDRAVRENKRIAILPDG--SLRILNASKSDE-GKYVCRGENVFGSA-EIIASLSVKEPT 572
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS----FTWSKNGVKLPVNTSTKYFAEFHK 412
++ +P ++ VG+ ++ CK++ S F W+ G + +F
Sbjct: 573 RIELTPK--RTELTVGE--SIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRA 628
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHS 472
++ L+I N+ G Y C + + +L V P + V +T S
Sbjct: 629 Q---ASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITES 685
Query: 473 TVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATN--FTVHGLEKN--TDYI 527
T TL W P D S Y ++ R F ++ +P+ T + ++ N +Y
Sbjct: 686 TATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYE 745
Query: 528 FSVMAINKIG 537
F V+A N IG
Sbjct: 746 FRVVATNPIG 755
Score = 59.7 bits (138), Expect = 4e-08
Identities = 72/294 (24%), Positives = 116/294 (39%), Gaps = 35/294 (11%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIIS-EGSMLNMTKLTRHDAG 236
E + +++ + P I Y+W + P S + + R IS E L ++K+ D G
Sbjct: 209 EGQGVVLMCSPPPHSPEIIYSWVFNEFP---SFVAEDSRRFISQETGNLYISKVQTSDVG 265
Query: 237 IYTCEAVNSQGAA----------VANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAI 285
Y C N+ A + N V Y I+ V A + C A+
Sbjct: 266 SYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFAL 325
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
GNP+ I W + I K+ + + L I + ++ G ++C N G +
Sbjct: 326 GNPVPT--ITWMKVNGYIPSKA---RLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSF 380
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
+ + + + P N + S G R CK P P++ W KNGV L + +
Sbjct: 381 RGQLQVYTY-PHWVEKLNDTQLDS--GSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVE 437
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV-TSAP 458
VL+I+NV SD G Y+C A N+ G + +L + SAP
Sbjct: 438 MV-----------NGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAP 480
Score = 57.2 bits (132), Expect = 2e-07
Identities = 75/328 (22%), Positives = 137/328 (41%), Gaps = 34/328 (10%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
+ + + ++ GNP +Y W ++G T+ S + +G+ + D+G
Sbjct: 115 DEKKVALNCEVRGNPVP-SYRWLRNG---TEIDLESDYRYSLIDGTFIISNPSEAKDSGH 170
Query: 238 YTCEAVNSQGAAVAN-ISVSVHYPAGIKSVSQNVVA-NPNEDAVLSCTAIGNPLLAEHI- 294
Y C A N+ G+ ++ ++ Y +++ V+ + VL C+ P E I
Sbjct: 171 YQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSP--PPHSPEIIY 228
Query: 295 KWERKGYK--IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA--------- 343
W + + S F + T L I K ++ ++G++ C+V N + +A
Sbjct: 229 SWVFNEFPSFVAEDSRRFISQE-TGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPL 287
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTS 403
T ++ ++ +++P+++ F +A+ G ++ C P P+ TW K +P
Sbjct: 288 TLRNDGVMGEYEPKIEVHFPFTVTAAK-GTTVKMECFALGNPVPTITWMKVNGYIPSK-- 344
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
A K+ +VL I NV D G YEC A N G ++ +L V + P V
Sbjct: 345 ----ARLRKSQ-----AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEK 395
Query: 464 LTVTNVTHSTVTLEWVPGFDGGLQSWYR 491
L T + S L W G + YR
Sbjct: 396 LNDTQL-DSGSPLRWECKATGKPRPTYR 422
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/196 (24%), Positives = 85/196 (43%), Gaps = 12/196 (6%)
Query: 162 NAPIFDDTTSYNTVGI-ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIIS 220
+AP F T+ + +++ ++I + G+P T +W K + ++ + I+
Sbjct: 478 SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP-TISWKKGDRAVRENKRIA----ILP 532
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVL 280
+GS L + ++ D G Y C N G+A S+SV P I+ + E VL
Sbjct: 533 DGS-LRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVL 591
Query: 281 SCTAIGNPLLAEHIKWERKGYKID--PKSVTFE---PKNLTSYLIIRKAKSENLGNFQCV 335
+C AI + L W KG ID + FE + ++ L+IR + G + C
Sbjct: 592 NCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCR 651
Query: 336 VNNGIGSATKQDVMLI 351
V S + + +L+
Sbjct: 652 VQTTADSVSDEAELLV 667
Score = 45.6 bits (103), Expect = 7e-04
Identities = 41/138 (29%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 24 PMITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISI 82
P I + P T AA GT K+ C + G NP+ T+TW K + I S K + A + I
Sbjct: 300 PKIEVHFPFTVTAAKGTTVKMECFALG-NPVPTITWMKVNGYIPS--KARLRKSQAVLEI 356
Query: 83 LTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDS 142
D+ Y C A NS + L V+ P V+ + L G C
Sbjct: 357 PNVQLDDAGIYECRAENSRGKNSF--RGQLQVYTYPHWVE-KLNDTQLDSGSPLRWEC-K 412
Query: 143 ASSNPPATLSWWRDGIPV 160
A+ P T W ++G+P+
Sbjct: 413 ATGKPRPTYRWLKNGVPL 430
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 87.0 bits (206), Expect = 2e-16
Identities = 97/384 (25%), Positives = 164/384 (42%), Gaps = 49/384 (12%)
Query: 187 RADGNPPS-ITYTWTKDGLPITQSSYSSGNDRIIS-EGSMLNMTKLTRHDAGIYTCEAVN 244
+ +PP+ IT+ + + LP+T DRI + +L + +++ D+G Y C A
Sbjct: 157 KISSHPPAVITWEFNRTTLPMTM-------DRITALPTGVLQIYDVSQRDSGNYRCIAAT 209
Query: 245 ------SQGAAVANI----SVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHI 294
S A++ I S S H P I QN+ + ++ VL C A GNP I
Sbjct: 210 VAHRRKSMEASLTVIPAKESKSFHTPTIIAG-PQNITTSLHQTVVLECMATGNP--KPII 266
Query: 295 KWERKGYKIDPKSV-TFEPKNL-TSYLIIRKAKSENLGNFQC-VVNNGIGSATKQDVMLI 351
W R +D KS+ F + L L+I + ++ G + C G + T L
Sbjct: 267 SWSR----LDHKSIDVFNTRVLGNGNLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLT 322
Query: 352 VKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
V P P + + G R +C+ + +P+P +W KNG K+ H
Sbjct: 323 VLAPPSFVEWPESL-TRPRAG-TARFVCQAEGIPSPKMSWLKNGRKI------------H 368
Query: 412 KNDHI-TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA---PDQVVSLTVT 467
N I Y S L+IN + D Y+C A N G + +L V + P ++
Sbjct: 369 SNGRIKMYNSKLVINQIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPSAPYNVHAE 428
Query: 468 NVTHSTVTLEWV-PGFDGGLQSWYRIRYRKVFD-DSYKYEDVLPKHATNFTVHGLEKNTD 525
++ S + L W P ++ Y + Y K ++ +Y+ V+ T++ + LE ++
Sbjct: 429 TMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASN 488
Query: 526 YIFSVMAINKIGQSKYRPDDTKAT 549
Y F ++A +G S+ T+ T
Sbjct: 489 YTFYIVAYMPMGASQMSDHVTQNT 512
Score = 52.0 bits (119), Expect = 8e-06
Identities = 60/246 (24%), Positives = 94/246 (38%), Gaps = 31/246 (12%)
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLII---RKA 324
Q+V + VL C A G + + W + G K+ N + Y+ R+
Sbjct: 46 QDVTVTRKDPVVLDCQAHGEVPIK--VTWLKNGAKMSENKRIEVLSNGSLYISEVEGRRG 103
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSV 384
+ + G +QC+ N G+ Q L + + P + + + G V R CK S
Sbjct: 104 EQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQP--ISTEVHEGGVARFACKISSH 161
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY--TSVLLINNVATSDYGSYECGA--- 439
P TW N LP+ D IT T VL I +V+ D G+Y C A
Sbjct: 162 PPAVITWEFNRTTLPMTM-----------DRITALPTGVLQIYDVSQRDSGNYRCIAATV 210
Query: 440 ---RNELGFSTTTVKLDVTSA---PDQVVS-LTVTNVTHSTVTLE-WVPGFDGGLQSWYR 491
R + S T + + + P + +T H TV LE G + SW R
Sbjct: 211 AHRRKSMEASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSR 270
Query: 492 IRYRKV 497
+ ++ +
Sbjct: 271 LDHKSI 276
Score = 42.7 bits (96), Expect = 0.005
Identities = 64/297 (21%), Positives = 113/297 (38%), Gaps = 35/297 (11%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSM----LNMTKLTRHDA 235
+P+++ +A G P I TW K+G ++++ ++S GS+ + + + D
Sbjct: 54 DPVVLDCQAHGEVP-IKVTWLKNGAKMSENK----RIEVLSNGSLYISEVEGRRGEQSDE 108
Query: 236 GIYTCEAVNSQGAAV---ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
G Y C A+N GA + A++++S ++ +S V + A +C +P
Sbjct: 109 GFYQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEV--HEGGVARFACKISSHPPAVI 166
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
++ R + +T P T L I + GN++C+ + L V
Sbjct: 167 TWEFNRTTLPMTMDRITALP---TGVLQIYDVSQRDSGNYRCIAATVAHRRKSMEASLTV 223
Query: 353 KFKPEMDT--SPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
E + +P + N+ Q L C P P +WS+ K S
Sbjct: 224 IPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHK-----SIDV 278
Query: 407 FAEFHKNDHITYTSVLLINNVATSDYGSYECGAR--NELGFSTTTVKLDVTSAPDQV 461
F N + L+I++V G Y C A F+ L V + P V
Sbjct: 279 F-----NTRVLGNGNLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFV 330
Score = 35.9 bits (79), Expect = 0.60
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 37 AGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCE 96
AGT + C G P ++W KN +KIHS + K ++++ I + ++ A Y+C
Sbjct: 341 AGTA-RFVC-QAEGIPSPKMSWLKNGRKIHSNGRI--KMYNSKLVINQIIPEDDAIYQCM 396
Query: 97 ATNSATEI 104
A NS I
Sbjct: 397 AENSQGSI 404
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 87.0 bits (206), Expect = 2e-16
Identities = 88/370 (23%), Positives = 155/370 (41%), Gaps = 33/370 (8%)
Query: 181 PLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTC 240
PL +A G P TY W K+G+P++ S R+ +L + + + DAG+Y C
Sbjct: 332 PLRWECKATGKPRP-TYRWLKNGVPLSPQS------RVEMVNGVLMIHNVNQSDAGMYQC 384
Query: 241 EAVNSQGAAVANISVSVHYPA---GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
A N GA A+ + + A + + + ++ +++ V+ C G+P I W+
Sbjct: 385 LAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSP--KPTISWK 442
Query: 298 RKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ + + K + P S I+ +KS+ G + C N GSA + L VK
Sbjct: 443 KGDRAVRENKRIAILPDG--SLRILNASKSDE-GKYVCRGENVFGSA-EIIASLSVKEPT 498
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS----FTWSKNGVKLPVNTSTKYFAEFHK 412
++ +P ++ VG+ ++ CK++ S F W+ G + +F
Sbjct: 499 RIELTPK--RTELTVGE--SIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRA 554
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHS 472
++ L+I N+ G Y C + + +L V P + V +T S
Sbjct: 555 Q---ASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITES 611
Query: 473 TVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATN--FTVHGLEKN--TDYI 527
T TL W P D S Y ++ R F ++ +P+ T + ++ N +Y
Sbjct: 612 TATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYE 671
Query: 528 FSVMAINKIG 537
F V+A N IG
Sbjct: 672 FRVVATNPIG 681
Score = 59.7 bits (138), Expect = 4e-08
Identities = 72/294 (24%), Positives = 116/294 (39%), Gaps = 35/294 (11%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIIS-EGSMLNMTKLTRHDAG 236
E + +++ + P I Y+W + P S + + R IS E L ++K+ D G
Sbjct: 135 EGQGVVLMCSPPPHSPEIIYSWVFNEFP---SFVAEDSRRFISQETGNLYISKVQTSDVG 191
Query: 237 IYTCEAVNSQGAA----------VANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAI 285
Y C N+ A + N V Y I+ V A + C A+
Sbjct: 192 SYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFAL 251
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
GNP+ I W + I K+ + + L I + ++ G ++C N G +
Sbjct: 252 GNPVPT--ITWMKVNGYIPSKA---RLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSF 306
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
+ + + + P N + S G R CK P P++ W KNGV L + +
Sbjct: 307 RGQLQVYTY-PHWVEKLNDTQLDS--GSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVE 363
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV-TSAP 458
VL+I+NV SD G Y+C A N+ G + +L + SAP
Sbjct: 364 MV-----------NGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAP 406
Score = 57.2 bits (132), Expect = 2e-07
Identities = 75/328 (22%), Positives = 137/328 (41%), Gaps = 34/328 (10%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
+ + + ++ GNP +Y W ++G T+ S + +G+ + D+G
Sbjct: 41 DEKKVALNCEVRGNPVP-SYRWLRNG---TEIDLESDYRYSLIDGTFIISNPSEAKDSGH 96
Query: 238 YTCEAVNSQGAAVAN-ISVSVHYPAGIKSVSQNVVA-NPNEDAVLSCTAIGNPLLAEHI- 294
Y C A N+ G+ ++ ++ Y +++ V+ + VL C+ P E I
Sbjct: 97 YQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSP--PPHSPEIIY 154
Query: 295 KWERKGYK--IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA--------- 343
W + + S F + T L I K ++ ++G++ C+V N + +A
Sbjct: 155 SWVFNEFPSFVAEDSRRFISQE-TGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPL 213
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTS 403
T ++ ++ +++P+++ F +A+ G ++ C P P+ TW K +P
Sbjct: 214 TLRNDGVMGEYEPKIEVHFPFTVTAAK-GTTVKMECFALGNPVPTITWMKVNGYIPSK-- 270
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
A K+ +VL I NV D G YEC A N G ++ +L V + P V
Sbjct: 271 ----ARLRKSQ-----AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEK 321
Query: 464 LTVTNVTHSTVTLEWVPGFDGGLQSWYR 491
L T + S L W G + YR
Sbjct: 322 LNDTQL-DSGSPLRWECKATGKPRPTYR 348
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/196 (24%), Positives = 85/196 (43%), Gaps = 12/196 (6%)
Query: 162 NAPIFDDTTSYNTVGI-ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIIS 220
+AP F T+ + +++ ++I + G+P T +W K + ++ + I+
Sbjct: 404 SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP-TISWKKGDRAVRENKRIA----ILP 458
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVL 280
+GS L + ++ D G Y C N G+A S+SV P I+ + E VL
Sbjct: 459 DGS-LRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVL 517
Query: 281 SCTAIGNPLLAEHIKWERKGYKID--PKSVTFE---PKNLTSYLIIRKAKSENLGNFQCV 335
+C AI + L W KG ID + FE + ++ L+IR + G + C
Sbjct: 518 NCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCR 577
Query: 336 VNNGIGSATKQDVMLI 351
V S + + +L+
Sbjct: 578 VQTTADSVSDEAELLV 593
Score = 45.6 bits (103), Expect = 7e-04
Identities = 41/138 (29%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 24 PMITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISI 82
P I + P T AA GT K+ C + G NP+ T+TW K + I S K + A + I
Sbjct: 226 PKIEVHFPFTVTAAKGTTVKMECFALG-NPVPTITWMKVNGYIPS--KARLRKSQAVLEI 282
Query: 83 LTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDS 142
D+ Y C A NS + L V+ P V+ + L G C
Sbjct: 283 PNVQLDDAGIYECRAENSRGKNSF--RGQLQVYTYPHWVE-KLNDTQLDSGSPLRWEC-K 338
Query: 143 ASSNPPATLSWWRDGIPV 160
A+ P T W ++G+P+
Sbjct: 339 ATGKPRPTYRWLKNGVPL 356
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 87.0 bits (206), Expect = 2e-16
Identities = 88/370 (23%), Positives = 155/370 (41%), Gaps = 33/370 (8%)
Query: 181 PLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTC 240
PL +A G P TY W K+G+P++ S R+ +L + + + DAG+Y C
Sbjct: 406 PLRWECKATGKPRP-TYRWLKNGVPLSPQS------RVEMVNGVLMIHNVNQSDAGMYQC 458
Query: 241 EAVNSQGAAVANISVSVHYPA---GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
A N GA A+ + + A + + + ++ +++ V+ C G+P I W+
Sbjct: 459 LAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSP--KPTISWK 516
Query: 298 RKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
+ + + K + P S I+ +KS+ G + C N GSA + L VK
Sbjct: 517 KGDRAVRENKRIAILPDG--SLRILNASKSDE-GKYVCRGENVFGSA-EIIASLSVKEPT 572
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS----FTWSKNGVKLPVNTSTKYFAEFHK 412
++ +P ++ VG+ ++ CK++ S F W+ G + +F
Sbjct: 573 RIELTPK--RTELTVGE--SIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRA 628
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHS 472
++ L+I N+ G Y C + + +L V P + V +T S
Sbjct: 629 Q---ASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITES 685
Query: 473 TVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATN--FTVHGLEKN--TDYI 527
T TL W P D S Y ++ R F ++ +P+ T + ++ N +Y
Sbjct: 686 TATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYE 745
Query: 528 FSVMAINKIG 537
F V+A N IG
Sbjct: 746 FRVVATNPIG 755
Score = 59.7 bits (138), Expect = 4e-08
Identities = 72/294 (24%), Positives = 116/294 (39%), Gaps = 35/294 (11%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIIS-EGSMLNMTKLTRHDAG 236
E + +++ + P I Y+W + P S + + R IS E L ++K+ D G
Sbjct: 209 EGQGVVLMCSPPPHSPEIIYSWVFNEFP---SFVAEDSRRFISQETGNLYISKVQTSDVG 265
Query: 237 IYTCEAVNSQGAA----------VANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAI 285
Y C N+ A + N V Y I+ V A + C A+
Sbjct: 266 SYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFAL 325
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATK 345
GNP+ I W + I K+ + + L I + ++ G ++C N G +
Sbjct: 326 GNPVPT--ITWMKVNGYIPSKA---RLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSF 380
Query: 346 QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK 405
+ + + + P N + S G R CK P P++ W KNGV L + +
Sbjct: 381 RGQLQVYTY-PHWVEKLNDTQLDS--GSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVE 437
Query: 406 YFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV-TSAP 458
VL+I+NV SD G Y+C A N+ G + +L + SAP
Sbjct: 438 MV-----------NGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAP 480
Score = 57.2 bits (132), Expect = 2e-07
Identities = 75/328 (22%), Positives = 137/328 (41%), Gaps = 34/328 (10%)
Query: 178 ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
+ + + ++ GNP +Y W ++G T+ S + +G+ + D+G
Sbjct: 115 DEKKVALNCEVRGNPVP-SYRWLRNG---TEIDLESDYRYSLIDGTFIISNPSEAKDSGH 170
Query: 238 YTCEAVNSQGAAVAN-ISVSVHYPAGIKSVSQNVVA-NPNEDAVLSCTAIGNPLLAEHI- 294
Y C A N+ G+ ++ ++ Y +++ V+ + VL C+ P E I
Sbjct: 171 YQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSP--PPHSPEIIY 228
Query: 295 KWERKGYK--IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA--------- 343
W + + S F + T L I K ++ ++G++ C+V N + +A
Sbjct: 229 SWVFNEFPSFVAEDSRRFISQE-TGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPL 287
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTS 403
T ++ ++ +++P+++ F +A+ G ++ C P P+ TW K +P
Sbjct: 288 TLRNDGVMGEYEPKIEVHFPFTVTAAK-GTTVKMECFALGNPVPTITWMKVNGYIPSK-- 344
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
A K+ +VL I NV D G YEC A N G ++ +L V + P V
Sbjct: 345 ----ARLRKSQ-----AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEK 395
Query: 464 LTVTNVTHSTVTLEWVPGFDGGLQSWYR 491
L T + S L W G + YR
Sbjct: 396 LNDTQL-DSGSPLRWECKATGKPRPTYR 422
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/196 (24%), Positives = 85/196 (43%), Gaps = 12/196 (6%)
Query: 162 NAPIFDDTTSYNTVGI-ENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIIS 220
+AP F T+ + +++ ++I + G+P T +W K + ++ + I+
Sbjct: 478 SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP-TISWKKGDRAVRENKRIA----ILP 532
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVL 280
+GS L + ++ D G Y C N G+A S+SV P I+ + E VL
Sbjct: 533 DGS-LRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVL 591
Query: 281 SCTAIGNPLLAEHIKWERKGYKID--PKSVTFE---PKNLTSYLIIRKAKSENLGNFQCV 335
+C AI + L W KG ID + FE + ++ L+IR + G + C
Sbjct: 592 NCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCR 651
Query: 336 VNNGIGSATKQDVMLI 351
V S + + +L+
Sbjct: 652 VQTTADSVSDEAELLV 667
Score = 45.6 bits (103), Expect = 7e-04
Identities = 41/138 (29%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 24 PMITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISI 82
P I + P T AA GT K+ C + G NP+ T+TW K + I S K + A + I
Sbjct: 300 PKIEVHFPFTVTAAKGTTVKMECFALG-NPVPTITWMKVNGYIPS--KARLRKSQAVLEI 356
Query: 83 LTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDS 142
D+ Y C A NS + L V+ P V+ + L G C
Sbjct: 357 PNVQLDDAGIYECRAENSRGKNSF--RGQLQVYTYPHWVE-KLNDTQLDSGSPLRWEC-K 412
Query: 143 ASSNPPATLSWWRDGIPV 160
A+ P T W ++G+P+
Sbjct: 413 ATGKPRPTYRWLKNGVPL 430
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 86.6 bits (205), Expect = 3e-16
Identities = 105/492 (21%), Positives = 186/492 (37%), Gaps = 62/492 (12%)
Query: 5 KDSGIFKCMINSPSDP---------PSAPMITG-YVPGTTLAAGTVQKLACISTGGNPLA 54
+D+G++ C+ SP+ + P I G P + Q + S P
Sbjct: 468 RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 527
Query: 55 TLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+TW ++ + T + + T + Y C A N+A + + +
Sbjct: 528 KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSV--AFRVEI 585
Query: 115 HFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATL-SWWRDGIPVQ-NAPIFD----- 167
H P +R+ P + + T + + PA L SW +D +P+ +P F+
Sbjct: 586 HTVPT---IRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG 642
Query: 168 ----------DTTSY-----NTVGIENEP------LIISVRADGNPPSITYTWTKDGLPI 206
D Y N+ G + + ++ A G+P + W KDG +
Sbjct: 643 SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLALLPCEASGSPKPLV-VWWKDGQKL 701
Query: 207 TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSV 266
G R++ ++L +T D+ + C N G A V+VH P I
Sbjct: 702 -DFRLQQGAYRLLPSNALL-LTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADD 759
Query: 267 SQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKS 326
+ VL+C + G P A + W + G ++ + + + + L I +A
Sbjct: 760 QTDFTVTMMAPVVLTCHSTGIP--APTVSWSKAGAQLGARGSGYR-VSPSGALEIGQALP 816
Query: 327 ENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPA 386
+ G + C N G A K V L V+ P + P+ V++ + + L C+ +P
Sbjct: 817 IHAGRYTCSARNSAGVAHKH-VFLTVQASPVVKPLPSVVRAVAE--EEVLLPCEASGIPR 873
Query: 387 PSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFS 446
P+ TW K G+ + ST+ + L I + + D G+Y C A+N G +
Sbjct: 874 PTITWQKEGLNVATGVSTQ----------VLPGGQLRIAHASPEDAGNYLCIAKNSAGSA 923
Query: 447 TTTVKLDVTSAP 458
+L V P
Sbjct: 924 MGKTRLVVQVPP 935
Score = 82.2 bits (194), Expect = 7e-15
Identities = 74/301 (24%), Positives = 123/301 (40%), Gaps = 24/301 (7%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ VQ +P+ S + E +++ A G P T TW K+GL + ++G
Sbjct: 839 LTVQASPVVKPLPSV-VRAVAEEEVLLPCEASGIPRP-TITWQKEGLNV-----ATGVST 891
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
+ G L + + DAG Y C A NS G+A+ + V P I++ ++
Sbjct: 892 QVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSH 951
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
A L C A G+P +I W++ G + F + + L+++ + ++ G + C
Sbjct: 952 AFLPCKARGSP--EPNITWDKDGQPVSGAEGKFTIQP-SGELLVKNLEGQDAGTYTCTAE 1008
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
N +G A ++ V L + P T P + +G L C + P P W+ N
Sbjct: 1009 NAVGRARRR-VHLTILVLPVFTTLPG--DRSLRLGDRLWLRCAARGSPTPRIGWTVN--D 1063
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
PV + D S L V+ D G+Y C A N +G + + V A
Sbjct: 1064 RPVTEGVS------EQDG---GSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA 1114
Query: 458 P 458
P
Sbjct: 1115 P 1115
Score = 81.0 bits (191), Expect = 2e-14
Identities = 75/297 (25%), Positives = 129/297 (43%), Gaps = 33/297 (11%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+ VQ P F++ + + PL+++ G P+ T TW KD +P+ S+
Sbjct: 31 LTVQVPPTFENPKTETVSQVAGSPLVLTCDVSG-VPAPTVTWLKDRMPVESSAVHG---- 85
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKS--VSQNVVANPN 275
++S G L +++L AG YTC A N+Q A + V+V I+S V++
Sbjct: 86 VVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEG 145
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSY-----LIIRKAKSENLG 330
++ L C A G P + W + G P P +L Y L+++ + + G
Sbjct: 146 QEVRLDCEADGQP--PPDVAWLKDG---SPLGQDMGP-HLRFYLDGGSLVLKGLWASDAG 199
Query: 331 NFQCVVNNGIGSATK---QDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP 387
+ CV +N G + +V++ K D S V S G++ ++C + P
Sbjct: 200 AYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLV---SRPGELVTMVCPVRGSPPI 256
Query: 388 SFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+W K+G+ LP++ T H + H L I+ V +D G + C A + G
Sbjct: 257 HVSWLKDGLPLPLSQRTL----LHGSGH-----TLRISKVQLADAGIFTCVAASPAG 304
Score = 75.8 bits (178), Expect = 6e-13
Identities = 77/291 (26%), Positives = 119/291 (40%), Gaps = 27/291 (9%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGN 215
+ V P +D+ + + P+ + A G P P+IT W KDG +T+ +S
Sbjct: 399 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNIT--WHKDGQALTRLENNSRA 456
Query: 216 DRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVS--QNVVAN 273
R+ L + + DAG+YTC A + GA + V V P I + VV
Sbjct: 457 TRV------LRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGL 510
Query: 274 PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
VL C+ P A I W R G + + T P+ +L ++ + + G++
Sbjct: 511 APGQLVLECSVEAEP--APKITWHRDGIVLQEDAHTQFPER-GRFLQLQALSTADSGDYS 567
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK 393
C N GS T + + P + + P V + N Q L C+ VPAP +W K
Sbjct: 568 CTARNAAGS-TSVAFRVEIHTVPTIRSGPPAVNVSVN--QTALLPCQADGVPAPLVSWRK 624
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++P++ + F I L I V D G Y C A N G
Sbjct: 625 D--RVPLDPRSPRF-------EILPEGSLRIQPVLAQDAGHYLCLASNSAG 666
Score = 74.9 bits (176), Expect = 1e-12
Identities = 65/263 (24%), Positives = 109/263 (41%), Gaps = 24/263 (9%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P+ WT + P+T+ GS L ++R D+G Y C A N G A
Sbjct: 1053 PTPRIGWTVNDRPVTEGVSEQDG------GSTLQRAAVSREDSGTYVCWAENRVGRTQAV 1106
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE 311
V V ++ + + + P ++ L C G+P+ I W + G + + +
Sbjct: 1107 SFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPV--PDIHWIKDGLPLRGSHLRHQ 1164
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV 371
+N L I + + ++ G +QC+ N +G A K+ V+L+++ P P + S
Sbjct: 1165 LQN--GSLTIHRTERDDAGRYQCLAENEMGVA-KKVVILVLQSAPVFQVEPQDMTVRS-- 1219
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G L C+ P P+ W + G L + + + L + NV T D
Sbjct: 1220 GDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPD----------GSLWLENVETGD 1269
Query: 432 YGSYECGARNELGFSTTTVKLDV 454
G+Y+C A N LG +T L V
Sbjct: 1270 AGTYDCVAHNLLGSATARAFLVV 1292
Score = 72.5 bits (170), Expect = 6e-12
Identities = 74/307 (24%), Positives = 127/307 (41%), Gaps = 31/307 (10%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P ++ KDG P+ S + +G L + + D+G Y+C AV+ G A +
Sbjct: 345 PCLSCRGMKDGEPLLSQS--------LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 396
Query: 253 ISVSVHYPAGIKSVSQ--NVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTF 310
++V P I+ Q + P L C A G P +I W + G +
Sbjct: 397 FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTP--QPNITWHKDGQALTRLE--- 451
Query: 311 EPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DTSPNFVKSA 368
T L + + + G + C+ + G A ++ + V+ P + P FV
Sbjct: 452 NNSRATRVLRVENVQVRDAGLYTCLAESPAG-AIEKSFRVRVQAPPNIVGPRGPRFVVGL 510
Query: 369 SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVA 428
+ GQ+ L C ++ PAP TW ++G+ L + T+ F E + L + ++
Sbjct: 511 AP-GQLV-LECSVEAEPAPKITWHRDGIVLQEDAHTQ-FPERGR--------FLQLQALS 559
Query: 429 TSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT-HSTVTLE-WVPGFDGGL 486
T+D G Y C ARN G ++ ++++ + P NV+ + T L G L
Sbjct: 560 TADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPL 619
Query: 487 QSWYRIR 493
SW + R
Sbjct: 620 VSWRKDR 626
Score = 70.9 bits (166), Expect = 2e-11
Identities = 77/284 (27%), Positives = 117/284 (41%), Gaps = 28/284 (9%)
Query: 178 ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
E + +A G+P P+IT W KDG P+ S + G I G +L + L DAG
Sbjct: 948 EGSHAFLPCKARGSPEPNIT--WDKDGQPV---SGAEGKFTIQPSGELL-VKNLEGQDAG 1001
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
YTC A N+ G A + +++ ++ + + L C A G+P
Sbjct: 1002 TYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPT------- 1054
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKA--KSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
R G+ ++ + VT +++A E+ G + C N +G T+ + VK
Sbjct: 1055 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGR-TQAVSFVHVKE 1113
Query: 355 KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + F VG +L C + P P W K+G LP+ S H
Sbjct: 1114 APVLQGEA-FSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDG--LPLRGS-------HLR- 1162
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
H L I+ D G Y+C A NE+G + V L + SAP
Sbjct: 1163 HQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAP 1206
Score = 59.7 bits (138), Expect = 4e-08
Identities = 71/284 (25%), Positives = 113/284 (39%), Gaps = 48/284 (16%)
Query: 190 GNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA 249
G+PP I +W KDGLP+ S + + G L ++K+ DAGI+TC A + G A
Sbjct: 252 GSPP-IHVSWLKDGLPLPLSQRTL----LHGSGHTLRISKVQLADAGIFTCVAASPAGVA 306
Query: 250 VANISVSVHYPAGIKSVSQ----------NVVANPNEDAVLSCTAI--GNPLLAEHIKWE 297
N ++ S N A P LSC + G PLL++ ++
Sbjct: 307 DRNFTLQCPLSWSRWSSRMTWWWFVAPWWNSRARPGAFPCLSCRGMKDGEPLLSQSLE-- 364
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
+G + ++V + + G + CV + G A ++ L V P
Sbjct: 365 -QGPSLQLEAV----------------GAGDSGTYSCVAVSEAGEA-RRHFQLTVMEPPH 406
Query: 358 MDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
++ S + + G L+C + P P+ TW K+G L N
Sbjct: 407 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL---------TRLENNSRA- 456
Query: 418 YTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
T VL + NV D G Y C A + G + ++ V + P+ V
Sbjct: 457 -TRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIV 499
Score = 58.4 bits (135), Expect = 1e-07
Identities = 51/212 (24%), Positives = 84/212 (39%), Gaps = 12/212 (5%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVAN-PNEDAVLSCTAIGNPLLAE 292
D G+Y+C+ N G AV +++V P ++ V+ VL+C G P A
Sbjct: 10 DKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVP--AP 67
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W + ++ S + L + + + G + CV N A K D ++ V
Sbjct: 68 TVTWLKDRMPVE-SSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARK-DFVVAV 125
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P + +S + GQ RL C+ P P W K+G P+ F+
Sbjct: 126 LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDG--SPLGQDMGPHLRFYL 183
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ L++ + SD G+Y C A N G
Sbjct: 184 DG-----GSLVLKGLWASDAGAYTCVAHNPAG 210
Score = 41.5 bits (93), Expect = 0.012
Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 13/165 (7%)
Query: 6 DSGIFKCMI-NSPSDPPSAPMITGYVPGT---------TLAAGTVQKLACISTGGNPLAT 55
D G++ C + N + +T VP T + AG+ L C G P T
Sbjct: 10 DKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC-DVSGVPAPT 68
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+TW K+ + S+ + + + Y C A N+ E V + V
Sbjct: 69 VTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVA 128
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDGIPV 160
+ V E VL+ G E L C+ A PP ++W +DG P+
Sbjct: 129 PRIRSSGVAREHHVLE-GQEVRLDCE-ADGQPPPDVAWLKDGSPL 171
Score = 37.9 bits (84), Expect = 0.15
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 7/71 (9%)
Query: 93 YRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPD---VLKPGIEATLICDSASSNPPA 149
Y C A N A E TV + V P +K A+ V +PG T++C S PP
Sbjct: 201 YTCVAHNPAGEDARLHTVNVLV---PPTIKQGADGSGTLVSRPGELVTMVCPVRGS-PPI 256
Query: 150 TLSWWRDGIPV 160
+SW +DG+P+
Sbjct: 257 HVSWLKDGLPL 267
Score = 37.1 bits (82), Expect = 0.26
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 11/131 (8%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQ- 92
+L G +L C G P +TW K+ + + T+ + + + + + NV A
Sbjct: 417 SLTPGAPMELLC-DAQGTPQPNITWHKDGQAL---TRLENNSRATRVLRVENVQVRDAGL 472
Query: 93 YRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV--LKPGIEATLICDSASSNPPAT 150
Y C A + A I ++ + V P V R V L PG + L C S + P
Sbjct: 473 YTCLAESPAGAIE--KSFRVRVQAPPNIVGPRGPRFVVGLAPG-QLVLEC-SVEAEPAPK 528
Query: 151 LSWWRDGIPVQ 161
++W RDGI +Q
Sbjct: 529 ITWHRDGIVLQ 539
Score = 37.1 bits (82), Expect = 0.26
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 7/135 (5%)
Query: 30 VPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDN 89
+P A + L G P T+TW K + +T +T ++ I ++
Sbjct: 850 LPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNV-ATGVSTQVLPGGQLRIAHASPED 908
Query: 90 QAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDV-LKPGIEATLICDSASSNPP 148
Y C A NSA + + V P ++ PD+ G A L C A +P
Sbjct: 909 AGNYLCIAKNSAGSAMGKTRLVVQV---PPVIE-NGLPDLSTTEGSHAFLPC-KARGSPE 963
Query: 149 ATLSWWRDGIPVQNA 163
++W +DG PV A
Sbjct: 964 PNITWDKDGQPVSGA 978
Score = 35.9 bits (79), Expect = 0.60
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 93 YRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLS 152
Y C+ +N A E T TL V P + E G L CD S P T++
Sbjct: 14 YSCKVSNVAGEA--VRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD-VSGVPAPTVT 70
Query: 153 WWRDGIPVQNAPI 165
W +D +PV+++ +
Sbjct: 71 WLKDRMPVESSAV 83
>AY358331-1|AAQ88697.1| 344|Homo sapiens HNT protein.
Length = 344
Score = 85.8 bits (203), Expect = 6e-16
Identities = 59/229 (25%), Positives = 101/229 (44%), Gaps = 17/229 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V I +S ++ N + L+C A G P
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRP--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W I PK+V F ++ YL I+ E G+++C +N + + + V + V
Sbjct: 166 TVTWRH----ISPKAVGFVSED--EYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTV 219
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + + VGQ G L C+ +VP+ F W K+ +L K
Sbjct: 220 NYPPYISEAKG---TGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGV------K 270
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
++ + S L+ NV+ DYG+Y C A N+LG + ++ L A +V
Sbjct: 271 VENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPGAVSEV 319
Score = 54.8 bits (126), Expect = 1e-06
Identities = 49/183 (26%), Positives = 77/183 (42%), Gaps = 13/183 (7%)
Query: 177 IENEPLIISVRAD-----GNPPSITYTWTKDGLP-ITQSSYSSGNDRIISEGSMLNMTKL 230
++ P I+ + +D GN S+T T P +T S +SE L + +
Sbjct: 132 VQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGI 191
Query: 231 TRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPL 289
TR +G Y C A N A V + V+V+YP I S ++ + L C A P
Sbjct: 192 TREQSGDYECSASNDVAAPVVRRVKVTVNYPPYI-SEAKGTGVPVGQKGTLQCEASAVP- 249
Query: 290 LAEHIKWERKGYKI--DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQD 347
+ +W + ++ K V E + S LI + GN+ CV +N +G T
Sbjct: 250 -SAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGH-TNAS 307
Query: 348 VML 350
+ML
Sbjct: 308 IML 310
>AF126426-1|AAF37591.1| 344|Homo sapiens neurotrimin protein.
Length = 344
Score = 85.8 bits (203), Expect = 6e-16
Identities = 59/229 (25%), Positives = 101/229 (44%), Gaps = 17/229 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V I +S ++ N + L+C A G P
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRP--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W I PK+V F ++ YL I+ E G+++C +N + + + V + V
Sbjct: 166 TVTWRH----ISPKAVGFVSED--EYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTV 219
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + + VGQ G L C+ +VP+ F W K+ +L K
Sbjct: 220 NYPPYISEAKG---TGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGV------K 270
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
++ + S L+ NV+ DYG+Y C A N+LG + ++ L A +V
Sbjct: 271 VENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPGAVSEV 319
Score = 54.8 bits (126), Expect = 1e-06
Identities = 49/183 (26%), Positives = 77/183 (42%), Gaps = 13/183 (7%)
Query: 177 IENEPLIISVRAD-----GNPPSITYTWTKDGLP-ITQSSYSSGNDRIISEGSMLNMTKL 230
++ P I+ + +D GN S+T T P +T S +SE L + +
Sbjct: 132 VQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGI 191
Query: 231 TRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPL 289
TR +G Y C A N A V + V+V+YP I S ++ + L C A P
Sbjct: 192 TREQSGDYECSASNDVAAPVVRRVKVTVNYPPYI-SEAKGTGVPVGQKGTLQCEASAVP- 249
Query: 290 LAEHIKWERKGYKI--DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQD 347
+ +W + ++ K V E + S LI + GN+ CV +N +G T
Sbjct: 250 -SAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGH-TNAS 307
Query: 348 VML 350
+ML
Sbjct: 308 IML 310
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 85.4 bits (202), Expect = 7e-16
Identities = 92/378 (24%), Positives = 155/378 (41%), Gaps = 36/378 (9%)
Query: 175 VGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRH 233
+G+ +A G+P TW K G + + + + S G++L + L T
Sbjct: 43 IGVSGRVASFVCQATGDPKP-RVTWNKKGKKVNSQRFET-IEFDESAGAVLRIQPLRTPR 100
Query: 234 DAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIG 286
D +Y C A NS G + ++V P+G ++ Q V A + C A G
Sbjct: 101 DENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASG 160
Query: 287 NPLLAEHIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATK 345
NP I W + +DP + K L S L I ++ + G ++CV N G
Sbjct: 161 NP--DPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 346 QDVMLIVKFKPEMDTSPNF--VKSASNVGQVGRLMCKCKSV--PAPSFTWSKNGVKLPVN 401
L V+ + +P F + + + G + C +V P P W + L
Sbjct: 219 SPANLYVRVRR---VAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTP- 274
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
++D +VL + +V S + C A + LG ++ V S P
Sbjct: 275 ----------EDDMPVGRNVLELTDVKDSA-NYHPCVAMSSLGVIEAVAQITVKSLPKAP 323
Query: 462 VSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYR-KVFDDSYKYEDVLPKHATNFTVHGL 520
+ VT T +++T+ W G + S+Y I Y+ K D Y+ ++ + T +++ GL
Sbjct: 324 GTPMVTENTATSITITWDSGNPDPV-SYYVIEYKSKSQDGPYQIKEDIT--TTRYSIGGL 380
Query: 521 EKNTDYIFSVMAINKIGQ 538
N++Y V A+N IGQ
Sbjct: 381 SPNSEYEIWVSAVNSIGQ 398
Score = 49.2 bits (112), Expect = 6e-05
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 10/132 (7%)
Query: 37 AGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSAEISILTNVTDNQAQ- 92
+G V C +TG +P +TW K KK++S T D++ A + I T
Sbjct: 46 SGRVASFVCQATG-DPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENV 104
Query: 93 YRCEATNSATEIPLFETVT-LNVHFAPEA---VKVRAEPDVLKPGIEATLICDSASSNPP 148
Y C A NS EI + +T L P + + + V++ AT++C +AS NP
Sbjct: 105 YECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLC-AASGNPD 163
Query: 149 ATLSWWRDGIPV 160
++W++D +PV
Sbjct: 164 PEITWFKDFLPV 175
Score = 40.7 bits (91), Expect = 0.021
Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 11/98 (11%)
Query: 362 PNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
P F+K + G+V +C+ P P TW+K G K VN+ EF + +
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKK--VNSQRFETIEFDE----S 86
Query: 418 YTSVLLINNVAT-SDYGSYECGARNELGFSTTTVKLDV 454
+VL I + T D YEC A+N +G T KL V
Sbjct: 87 AGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTV 124
Score = 32.3 bits (70), Expect = 7.3
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 47 STGGNPLATLTWFKNDKKIHSTTKT--TDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+ GNP +TWFK+ + + + S + I ++ +Q +Y C ATNSA
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSA 213
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 85.4 bits (202), Expect = 7e-16
Identities = 92/378 (24%), Positives = 155/378 (41%), Gaps = 36/378 (9%)
Query: 175 VGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRH 233
+G+ +A G+P TW K G + + + + S G++L + L T
Sbjct: 43 IGVSGRVASFVCQATGDPKP-RVTWNKKGKKVNSQRFET-IEFDESAGAVLRIQPLRTPR 100
Query: 234 DAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVLSCTAIG 286
D +Y C A NS G + ++V P+G ++ Q V A + C A G
Sbjct: 101 DENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASG 160
Query: 287 NPLLAEHIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATK 345
NP I W + +DP + K L S L I ++ + G ++CV N G
Sbjct: 161 NP--DPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 346 QDVMLIVKFKPEMDTSPNF--VKSASNVGQVGRLMCKCKSV--PAPSFTWSKNGVKLPVN 401
L V+ + +P F + + + G + C +V P P W + L
Sbjct: 219 SPANLYVRVRR---VAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTP- 274
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
++D +VL + +V S + C A + LG ++ V S P
Sbjct: 275 ----------EDDMPVGRNVLELTDVKDSA-NYHPCVAMSSLGVIEAVAQITVKSLPKAP 323
Query: 462 VSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYR-KVFDDSYKYEDVLPKHATNFTVHGL 520
+ VT T +++T+ W G + S+Y I Y+ K D Y+ ++ + T +++ GL
Sbjct: 324 GTPMVTENTATSITITWDSGNPDPV-SYYVIEYKSKSQDGPYQIKEDIT--TTRYSIGGL 380
Query: 521 EKNTDYIFSVMAINKIGQ 538
N++Y V A+N IGQ
Sbjct: 381 SPNSEYEIWVSAVNSIGQ 398
Score = 49.2 bits (112), Expect = 6e-05
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 10/132 (7%)
Query: 37 AGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSAEISILTNVTDNQAQ- 92
+G V C +TG +P +TW K KK++S T D++ A + I T
Sbjct: 46 SGRVASFVCQATG-DPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENV 104
Query: 93 YRCEATNSATEIPLFETVT-LNVHFAPEA---VKVRAEPDVLKPGIEATLICDSASSNPP 148
Y C A NS EI + +T L P + + + V++ AT++C +AS NP
Sbjct: 105 YECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLC-AASGNPD 163
Query: 149 ATLSWWRDGIPV 160
++W++D +PV
Sbjct: 164 PEITWFKDFLPV 175
Score = 40.7 bits (91), Expect = 0.021
Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 11/98 (11%)
Query: 362 PNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
P F+K + G+V +C+ P P TW+K G K VN+ EF + +
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKK--VNSQRFETIEFDE----S 86
Query: 418 YTSVLLINNVAT-SDYGSYECGARNELGFSTTTVKLDV 454
+VL I + T D YEC A+N +G T KL V
Sbjct: 87 AGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTV 124
Score = 36.3 bits (80), Expect = 0.45
Identities = 114/565 (20%), Positives = 210/565 (37%), Gaps = 69/565 (12%)
Query: 47 STGGNPLATLTWFKNDKKIHSTTKT--TDKAVSAEISILTNVTDNQAQYRCEATNSATEI 104
+ GNP +TWFK+ + + + S + I ++ +Q +Y C ATNSA +
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSA-GV 215
Query: 105 PLFETVTLNVHFAPEAVKVRAEP--DVLKPGIEATLICDSASSNPPATLSWWR---DGIP 159
L V A + P + PG + C + S P + W + D P
Sbjct: 216 RYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGS-PMPYVKWMQGAEDLTP 274
Query: 160 VQNAPI---------FDDTTSY------NTVGIENEPLIISVRADGNPPSITYTWTKDGL 204
+ P+ D+ +Y +++G+ I+V++ P
Sbjct: 275 EDDMPVGRNVLELTDVKDSANYHPCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTAT 334
Query: 205 PITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIK 264
IT ++ SGN +S + +K D E + + ++ +S + Y +
Sbjct: 335 SIT-ITWDSGNPDPVSYYVIEYKSK--SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVS 391
Query: 265 SVSQNVVANPNEDAVLSC--TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL-TSYLII 321
+V+ P+E V A P + I EP L Y +
Sbjct: 392 AVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVY 451
Query: 322 RKAKSEN-LGNFQ-----CVVNNGIGSATKQD--VMLIVKFKPEMD---TSPNFVKSASN 370
+ E+ +GN+Q + +GS + + + ++ F D + P VK+
Sbjct: 452 YTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQG 511
Query: 371 V-GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH-------ITYTSVL 422
V GQ L + +S + + +WS + + KY F + DH T+
Sbjct: 512 VPGQPMNLRAEARSETSITLSWSPPRQE----SIIKYELLFREGDHGREVGRTFDPTTSY 567
Query: 423 LINNVATSDYGSYECGARNE--LGFSTTTVK----LDVTSAPDQVVSLTVTNVTHSTVTL 476
++ ++ + ++ AR+ LG T V+ SAP Q V +V + + +
Sbjct: 568 VVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVK--CVSVRSTAILV 625
Query: 477 EW---VPGFDGGLQSWYRIRYRKVFDDSYKYEDV--LPKHATNFTVHGLEKNTDYIFSVM 531
W P G Y +RYR + + + ++V +P T + LEK T Y + +
Sbjct: 626 SWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTV 685
Query: 532 AINKIGQSKYRPDDTKATTLTSSEV 556
A ++G P+ + T +V
Sbjct: 686 AHTEVGPG---PESSPVVVRTDEDV 707
>EF043567-1|ABK34282.1| 355|Homo sapiens neurotrimin variant 3
protein.
Length = 355
Score = 85.4 bits (202), Expect = 7e-16
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 17/220 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V I +S ++ N + L+C A G P
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRP--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W I PK+V F ++ YL I+ E G+++C +N + + + V + V
Sbjct: 166 TVTWRH----ISPKAVGFVSED--EYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTV 219
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + + VGQ G L C+ +VP+ F W K+ +L K
Sbjct: 220 NYPPYISEAKG---TGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGV------K 270
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
++ + S L+ NV+ DYG+Y C A N+LG + ++ L
Sbjct: 271 VENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIML 310
Score = 54.8 bits (126), Expect = 1e-06
Identities = 49/183 (26%), Positives = 77/183 (42%), Gaps = 13/183 (7%)
Query: 177 IENEPLIISVRAD-----GNPPSITYTWTKDGLP-ITQSSYSSGNDRIISEGSMLNMTKL 230
++ P I+ + +D GN S+T T P +T S +SE L + +
Sbjct: 132 VQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGI 191
Query: 231 TRHDAGIYTCEAVNSQGAAVAN-ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPL 289
TR +G Y C A N A V + V+V+YP I S ++ + L C A P
Sbjct: 192 TREQSGDYECSASNDVAAPVVRRVKVTVNYPPYI-SEAKGTGVPVGQKGTLQCEASAVP- 249
Query: 290 LAEHIKWERKGYKI--DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQD 347
+ +W + ++ K V E + S LI + GN+ CV +N +G T
Sbjct: 250 -SAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGH-TNAS 307
Query: 348 VML 350
+ML
Sbjct: 308 IML 310
>BC050716-1|AAH50716.1| 316|Homo sapiens HNT protein protein.
Length = 316
Score = 85.4 bits (202), Expect = 7e-16
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 17/220 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V I +S ++ N + L+C A G P
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRP--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W I PK+V F ++ YL I+ E G+++C +N + + + V + V
Sbjct: 166 TVTWRH----ISPKAVGFVSED--EYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTV 219
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + + VGQ G L C+ +VP+ F W K+ +L K
Sbjct: 220 NYPPYISEAKG---TGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGV------K 270
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
++ + S L+ NV+ DYG+Y C A N+LG + ++ L
Sbjct: 271 VENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIML 310
Score = 54.8 bits (126), Expect = 1e-06
Identities = 49/183 (26%), Positives = 77/183 (42%), Gaps = 13/183 (7%)
Query: 177 IENEPLIISVRAD-----GNPPSITYTWTKDGLP-ITQSSYSSGNDRIISEGSMLNMTKL 230
++ P I+ + +D GN S+T T P +T S +SE L + +
Sbjct: 132 VQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGI 191
Query: 231 TRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPL 289
TR +G Y C A N A V + V+V+YP I S ++ + L C A P
Sbjct: 192 TREQSGDYECSASNDVAAPVVRRVKVTVNYPPYI-SEAKGTGVPVGQKGTLQCEASAVP- 249
Query: 290 LAEHIKWERKGYKI--DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQD 347
+ +W + ++ K V E + S LI + GN+ CV +N +G T
Sbjct: 250 -SAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGH-TNAS 307
Query: 348 VML 350
+ML
Sbjct: 308 IML 310
>U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein.
Length = 338
Score = 85.0 bits (201), Expect = 1e-15
Identities = 60/228 (26%), Positives = 98/228 (42%), Gaps = 18/228 (7%)
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTA 284
L + K+ +D G YTC + + + V P I ++S +V N + L C A
Sbjct: 96 LRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMA 155
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSAT 344
G P I W + P FE + YL I E G ++C N + SA
Sbjct: 156 NGRP--EPVITWRH----LTPTGREFEGEE--EYLEILGITREQSGKYECKAANEVSSAD 207
Query: 345 KQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTST 404
+ V + V + P + S + + + G+ L C+ +VPAP F W ++ + +N++
Sbjct: 208 VKQVKVTVNYPPTITESKS---NEATTGRQASLKCEASAVPAPDFEWYRDDTR--INSAN 262
Query: 405 KYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
E + S L + NV YG+Y C A N+LG + ++ L
Sbjct: 263 G--LEIKSTEG---QSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVL 305
Score = 52.0 bits (119), Expect = 8e-06
Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAA-VANISVSVHYPAGIKSVSQNVVANPNEDAV 279
E L + +TR +G Y C+A N +A V + V+V+YP I N A A
Sbjct: 178 EEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSN-EATTGRQAS 236
Query: 280 LSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A P A +W R +I+ + + S L + E+ GN+ CV N
Sbjct: 237 LKCEASAVP--APDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAAN 294
Query: 339 GIG 341
+G
Sbjct: 295 KLG 297
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 85.0 bits (201), Expect = 1e-15
Identities = 100/395 (25%), Positives = 149/395 (37%), Gaps = 43/395 (10%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N V +E E + + G+P T W KD + + Y I + L + K
Sbjct: 233 NQVVLEEEAVEFRCQVQGDPQP-TVRWKKDDADLPRGRYD------IKDDYTLRIKKTMS 285
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
D G Y C A N G A+ +++V P ++ + C GNP A
Sbjct: 286 TDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPA- 344
Query: 293 HIKWERKG-----YKIDPKSVTFEPK-NLTSYLIIRKAKSENLGNFQC---VVNNGIGSA 343
+ W+++G + P+ + T L I + + G + C V I +
Sbjct: 345 -VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK 403
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTS 403
+ +V ++ +P V L CK P P +W K G P
Sbjct: 404 AQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDP 463
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA------ 457
E L I N+ SD G+Y C A + G ++ + LDVT +
Sbjct: 464 RATIQE---------QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISK 514
Query: 458 -------PDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIR-YRKVFDDSYKYEDVL 508
P VT+VT ++VTL W PG G L S Y I + + +S++
Sbjct: 515 NYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANH 574
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRP 543
K T +TV GL NT Y+F V AIN G S P
Sbjct: 575 VK-TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSP 608
Score = 66.9 bits (156), Expect = 3e-10
Identities = 70/280 (25%), Positives = 115/280 (41%), Gaps = 22/280 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
EP I+ + P T W KD + I +RI G L ++ + DAG+YT
Sbjct: 148 EPAILECQPPRGHPEPTIYWKKDKVRIDDKE-----ERISIRGGKLMISNTRKSDAGMYT 202
Query: 240 CEAVNSQG---AAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTAIGNPLLAEHIK 295
C N G + A ++V P ++ VV E+AV C G+P ++
Sbjct: 203 CVGTNMVGERDSDPAELTV-FERPTFLRRPINQVVL--EEEAVEFRCQVQGDP--QPTVR 257
Query: 296 WERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
W++ + P+ ++ K+ L I+K S + G + C+ N +G + L V+
Sbjct: 258 WKKDDADL-PRG-RYDIKD-DYTLRIKKTMSTDEGTYMCIAENRVGK-MEASATLTVRAP 313
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P+ P A G+ C+ K P P+ W K G + + + + +
Sbjct: 314 PQFVVRPRDQIVAQ--GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQP--QQPNSRCS 369
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVT 455
++ T L I N+ SD G Y C A G +L+VT
Sbjct: 370 VSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVT 409
Score = 48.0 bits (109), Expect = 1e-04
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 28/198 (14%)
Query: 259 YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-----DPKS-VTFEP 312
+P I +V+ + E L+C A G P I+W + G ++ DP+S P
Sbjct: 29 FPPRIVEHPSDVIVSKGEPTTLNCKAEGRP--TPTIEWYKDGERVETDKDDPRSHRMLLP 86
Query: 313 KNLTSYLII---RKAKSENLGNFQCVVNNGIGSATKQDVML-IVKFKPEMDTSPNFVKSA 368
+L I R++K + G++ CV N +G A ++ L + + + +P V A
Sbjct: 87 SGSLFFLRIVHGRRSKPDE-GSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVA 145
Query: 369 SNVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT-SVLLINN 426
+ G+ L C+ + P P+ W K+ V++ K + I+ L+I+N
Sbjct: 146 A--GEPAILECQPPRGHPEPTIYWKKDKVRID-----------DKEERISIRGGKLMISN 192
Query: 427 VATSDYGSYECGARNELG 444
SD G Y C N +G
Sbjct: 193 TRKSDAGMYTCVGTNMVG 210
Score = 35.1 bits (77), Expect = 1.0
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D P V+ S+V G+ L CK + P P+ W K+G ++ +
Sbjct: 28 DFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 87
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++ + D GSY C ARN LG
Sbjct: 88 GSLFFLRIVHGRRSKPDEGSYVCVARNYLG 117
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 85.0 bits (201), Expect = 1e-15
Identities = 100/395 (25%), Positives = 149/395 (37%), Gaps = 43/395 (10%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N V +E E + + G+P T W KD + + Y I + L + K
Sbjct: 249 NQVVLEEEAVEFRCQVQGDPQP-TVRWKKDDADLPRGRYD------IKDDYTLRIKKTMS 301
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
D G Y C A N G A+ +++V P ++ + C GNP A
Sbjct: 302 TDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPA- 360
Query: 293 HIKWERKG-----YKIDPKSVTFEPK-NLTSYLIIRKAKSENLGNFQC---VVNNGIGSA 343
+ W+++G + P+ + T L I + + G + C V I +
Sbjct: 361 -VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK 419
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTS 403
+ +V ++ +P V L CK P P +W K G P
Sbjct: 420 AQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDP 479
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA------ 457
E L I N+ SD G+Y C A + G ++ + LDVT +
Sbjct: 480 RATIQE---------QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISK 530
Query: 458 -------PDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIR-YRKVFDDSYKYEDVL 508
P VT+VT ++VTL W PG G L S Y I + + +S++
Sbjct: 531 NYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANH 590
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRP 543
K T +TV GL NT Y+F V AIN G S P
Sbjct: 591 VK-TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSP 624
Score = 66.9 bits (156), Expect = 3e-10
Identities = 70/280 (25%), Positives = 115/280 (41%), Gaps = 22/280 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
EP I+ + P T W KD + I +RI G L ++ + DAG+YT
Sbjct: 164 EPAILECQPPRGHPEPTIYWKKDKVRIDDKE-----ERISIRGGKLMISNTRKSDAGMYT 218
Query: 240 CEAVNSQG---AAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTAIGNPLLAEHIK 295
C N G + A ++V P ++ VV E+AV C G+P ++
Sbjct: 219 CVGTNMVGERDSDPAELTV-FERPTFLRRPINQVVL--EEEAVEFRCQVQGDP--QPTVR 273
Query: 296 WERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
W++ + P+ ++ K+ L I+K S + G + C+ N +G + L V+
Sbjct: 274 WKKDDADL-PRG-RYDIKD-DYTLRIKKTMSTDEGTYMCIAENRVGK-MEASATLTVRAP 329
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P+ P A G+ C+ K P P+ W K G + + + + +
Sbjct: 330 PQFVVRPRDQIVAQ--GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQP--QQPNSRCS 385
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVT 455
++ T L I N+ SD G Y C A G +L+VT
Sbjct: 386 VSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVT 425
Score = 48.0 bits (109), Expect = 1e-04
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 28/198 (14%)
Query: 259 YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-----DPKS-VTFEP 312
+P I +V+ + E L+C A G P I+W + G ++ DP+S P
Sbjct: 45 FPPRIVEHPSDVIVSKGEPTTLNCKAEGRP--TPTIEWYKDGERVETDKDDPRSHRMLLP 102
Query: 313 KNLTSYLII---RKAKSENLGNFQCVVNNGIGSATKQDVML-IVKFKPEMDTSPNFVKSA 368
+L I R++K + G++ CV N +G A ++ L + + + +P V A
Sbjct: 103 SGSLFFLRIVHGRRSKPDE-GSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVA 161
Query: 369 SNVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT-SVLLINN 426
+ G+ L C+ + P P+ W K+ V++ K + I+ L+I+N
Sbjct: 162 A--GEPAILECQPPRGHPEPTIYWKKDKVRID-----------DKEERISIRGGKLMISN 208
Query: 427 VATSDYGSYECGARNELG 444
SD G Y C N +G
Sbjct: 209 TRKSDAGMYTCVGTNMVG 226
Score = 35.1 bits (77), Expect = 1.0
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D P V+ S+V G+ L CK + P P+ W K+G ++ +
Sbjct: 44 DFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 103
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++ + D GSY C ARN LG
Sbjct: 104 GSLFFLRIVHGRRSKPDEGSYVCVARNYLG 133
>BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associated
membrane protein protein.
Length = 338
Score = 85.0 bits (201), Expect = 1e-15
Identities = 60/228 (26%), Positives = 98/228 (42%), Gaps = 18/228 (7%)
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTA 284
L + K+ +D G YTC + + + V P I ++S +V N + L C A
Sbjct: 96 LRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMA 155
Query: 285 IGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSAT 344
G P I W + P FE + YL I E G ++C N + SA
Sbjct: 156 NGRP--EPVITWRH----LTPTGREFEGEE--EYLEILGITREQSGKYECKAANEVSSAD 207
Query: 345 KQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTST 404
+ V + V + P + S + + + G+ L C+ +VPAP F W ++ + +N++
Sbjct: 208 VKQVKVTVNYPPTITESKS---NEATTGRQASLKCEASAVPAPDFEWYRDDTR--INSAN 262
Query: 405 KYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
E + S L + NV YG+Y C A N+LG + ++ L
Sbjct: 263 G--LEIKSTEG---QSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVL 305
Score = 52.0 bits (119), Expect = 8e-06
Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAA-VANISVSVHYPAGIKSVSQNVVANPNEDAV 279
E L + +TR +G Y C+A N +A V + V+V+YP I N A A
Sbjct: 178 EEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSN-EATTGRQAS 236
Query: 280 LSCTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L C A P A +W R +I+ + + S L + E+ GN+ CV N
Sbjct: 237 LKCEASAVP--APDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAAN 294
Query: 339 GIG 341
+G
Sbjct: 295 KLG 297
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 85.0 bits (201), Expect = 1e-15
Identities = 100/395 (25%), Positives = 149/395 (37%), Gaps = 43/395 (10%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N V +E E + + G+P T W KD + + Y I + L + K
Sbjct: 235 NQVVLEEEAVEFRCQVQGDPQP-TVRWKKDDADLPRGRYD------IKDDYTLRIKKTMS 287
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
D G Y C A N G A+ +++V P ++ + C GNP A
Sbjct: 288 TDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPA- 346
Query: 293 HIKWERKG-----YKIDPKSVTFEPK-NLTSYLIIRKAKSENLGNFQC---VVNNGIGSA 343
+ W+++G + P+ + T L I + + G + C V I +
Sbjct: 347 -VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK 405
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTS 403
+ +V ++ +P V L CK P P +W K G P
Sbjct: 406 AQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDP 465
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA------ 457
E L I N+ SD G+Y C A + G ++ + LDVT +
Sbjct: 466 RATIQE---------QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISK 516
Query: 458 -------PDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIR-YRKVFDDSYKYEDVL 508
P VT+VT ++VTL W PG G L S Y I + + +S++
Sbjct: 517 NYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANH 576
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRP 543
K T +TV GL NT Y+F V AIN G S P
Sbjct: 577 VK-TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSP 610
Score = 66.9 bits (156), Expect = 3e-10
Identities = 70/280 (25%), Positives = 115/280 (41%), Gaps = 22/280 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
EP I+ + P T W KD + I +RI G L ++ + DAG+YT
Sbjct: 150 EPAILECQPPRGHPEPTIYWKKDKVRIDDKE-----ERISIRGGKLMISNTRKSDAGMYT 204
Query: 240 CEAVNSQG---AAVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTAIGNPLLAEHIK 295
C N G + A ++V P ++ VV E+AV C G+P ++
Sbjct: 205 CVGTNMVGERDSDPAELTV-FERPTFLRRPINQVVL--EEEAVEFRCQVQGDP--QPTVR 259
Query: 296 WERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
W++ + P+ ++ K+ L I+K S + G + C+ N +G + L V+
Sbjct: 260 WKKDDADL-PRG-RYDIKD-DYTLRIKKTMSTDEGTYMCIAENRVGK-MEASATLTVRAP 315
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P+ P A G+ C+ K P P+ W K G + + + + +
Sbjct: 316 PQFVVRPRDQIVAQ--GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQP--QQPNSRCS 371
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVT 455
++ T L I N+ SD G Y C A G +L+VT
Sbjct: 372 VSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVT 411
Score = 48.0 bits (109), Expect = 1e-04
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 28/198 (14%)
Query: 259 YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI-----DPKS-VTFEP 312
+P I +V+ + E L+C A G P I+W + G ++ DP+S P
Sbjct: 31 FPPRIVEHPSDVIVSKGEPTTLNCKAEGRP--TPTIEWYKDGERVETDKDDPRSHRMLLP 88
Query: 313 KNLTSYLII---RKAKSENLGNFQCVVNNGIGSATKQDVML-IVKFKPEMDTSPNFVKSA 368
+L I R++K + G++ CV N +G A ++ L + + + +P V A
Sbjct: 89 SGSLFFLRIVHGRRSKPDE-GSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVA 147
Query: 369 SNVGQVGRLMCK-CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT-SVLLINN 426
+ G+ L C+ + P P+ W K+ V++ K + I+ L+I+N
Sbjct: 148 A--GEPAILECQPPRGHPEPTIYWKKDKVRID-----------DKEERISIRGGKLMISN 194
Query: 427 VATSDYGSYECGARNELG 444
SD G Y C N +G
Sbjct: 195 TRKSDAGMYTCVGTNMVG 212
Score = 35.1 bits (77), Expect = 1.0
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 359 DTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
D P V+ S+V G+ L CK + P P+ W K+G ++ +
Sbjct: 30 DFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 89
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++ + D GSY C ARN LG
Sbjct: 90 GSLFFLRIVHGRRSKPDEGSYVCVARNYLG 119
>X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 84.6 bits (200), Expect = 1e-15
Identities = 104/421 (24%), Positives = 176/421 (41%), Gaps = 38/421 (9%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + + G E + + +G P P +T W +G+P+ + +
Sbjct: 327 VTVEAAPYWLHKPQSHLYG-PGETARLDCQVEGRPQPEVT--WRINGIPVEE--LAKDQK 381
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV-HYPAGIKSV-SQNVVANP 274
I G+++ ++ + D + CEA N G +AN + V PA I + +Q +A
Sbjct: 382 YRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ 440
Query: 275 NEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
A L C A G P+ + ++W + G + F N T L IR ++ + G +
Sbjct: 441 GSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERFFPYANGT--LGIRDLQANDTGRYF 496
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPA--PSFTW 391
C+ N + T +M +K K + + G C+ P+ PS TW
Sbjct: 497 CLAANDQNNVT---IMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW 553
Query: 392 SKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
+G L + S KYF E + L+I+++ SD G+Y C A EL +
Sbjct: 554 RGDGRDLQELGDSDKYFIEDGR---------LVIHSLDYSDQGNYSCVASTELDVVESRA 604
Query: 451 KLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFDGGLQ-SWYRIRY--RKVFDDSYKY 504
+L V +P V L +++ VT S V + W P D Y I + +++ + +
Sbjct: 605 QLLVVGSPGPVPRLVLSDLHLVTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYS 664
Query: 505 EDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVST 564
+P + T+ T+ L Y F V AINK G + P T +T E + V
Sbjct: 665 LGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE--PSPVSETVVTPEAAPEKNPVDV 721
Query: 565 E 565
+
Sbjct: 722 K 722
Score = 67.3 bits (157), Expect = 2e-10
Identities = 78/326 (23%), Positives = 123/326 (37%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I +P + +Y + N
Sbjct: 243 LFPTNSSTHLVALQGQPLVLECIAEGFPTPTIKSVRPSGPMPADRVTYQNHN-------K 295
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 296 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 355
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 356 VEGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 413
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 414 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 470
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 471 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 522
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 523 GPRSTIEKKGSRVTFTCQASFDPSLQ 548
Score = 38.3 bits (85), Expect = 0.11
Identities = 71/321 (22%), Positives = 121/321 (37%), Gaps = 32/321 (9%)
Query: 156 DGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSG 214
+G V P+ + + V + + + A G P + + WT+DG+ +
Sbjct: 27 EGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKP-EVQFRWTRDGVHFKPKEELGVT 85
Query: 215 NDRIISEGSML---NMTKLTRHDAGIYTCEAVNSQGAAVAN-ISVSVH-YPAGIKSVSQN 269
+ GS N + + GIY C A N G A+++ I + P K +
Sbjct: 86 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 145
Query: 270 VVANPNEDAVLSCT--AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V E VL C PL + + K D + + NL ++ S+
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVL---TSD 202
Query: 328 NLGNFQCVVN-NGIGS-ATKQDVMLIVKFKPEM-DTSPNFV---KSASNV----GQVGRL 377
N ++ C + GI + K+ + L VK M D P + S++++ GQ L
Sbjct: 203 NHSDYICHAHFPGIRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSTHLVALQGQPLVL 262
Query: 378 MCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
C + P P+ + +P + T ++N + L + V D G Y C
Sbjct: 263 ECIAEGFPTPTIKSVRPSGPMPADRVT------YQN----HNKTLQLLKVGEEDDGEYRC 312
Query: 438 GARNELGFSTTTVKLDVTSAP 458
A N LG + + V +AP
Sbjct: 313 LAENSLGSARHAYYVTVEAAP 333
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 84.6 bits (200), Expect = 1e-15
Identities = 64/239 (26%), Positives = 104/239 (43%), Gaps = 12/239 (5%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
S L + DAGIY C G+ + A ++V + K+ EDAV+
Sbjct: 79 STLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIV 138
Query: 282 CTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN-G 339
C + + L I W+ KG + K V F + +YL IR K + G ++C
Sbjct: 139 CDVVSS--LPPTIIWKHKGRDVILKKDVRFIVLS-NNYLQIRGIKKTDEGTYRCEGRILA 195
Query: 340 IGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
G +D+ +IV P + N V + +N+GQ L+C + P P+ +W+K+G ++
Sbjct: 196 RGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIE 255
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + +D +S L I V +D Y C A N+ G T+ L V + P
Sbjct: 256 QEEDDEKY--IFSDD----SSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 81.0 bits (191), Expect = 2e-14
Identities = 88/357 (24%), Positives = 146/357 (40%), Gaps = 26/357 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T +WTKDG I Q I S+ S L + K+ ++D Y C A N G A
Sbjct: 241 PEPTMSWTKDGEQIEQEE--DDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA 298
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE 311
I + V I V E L+C A G+P+ I W I + T +
Sbjct: 299 TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPI--PSITWRTSTRNISSEEKTLD 356
Query: 312 PKNL------TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFV 365
+ S L ++ + + G + C +N IG Q + L V++ P++ P V
Sbjct: 357 GHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ-DSQSMYLEVQYAPKLQ-GPVAV 414
Query: 366 KSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLIN 425
+ G + C+ + P+ + +W ++G LP S+ Y K + S L +
Sbjct: 415 YTWE--GNQVNITCEVFAYPSATISWFRDGQLLP---SSNY--SNIKIYNTPSASYLEVT 467
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDG 484
+ +D+G+Y C A N +G + L P S+ ST +++ P G
Sbjct: 468 PDSENDFGNYNCTAVNRIGQESLEFILVQADTPSS-PSIDQVEPYSSTAQVQFDEPEATG 526
Query: 485 GLQSW-YRIRYRKVFDDSYKYEDVLPKHATN---FTVHGLEKNTDYIFSVMAINKIG 537
G+ Y+ +R V ++ + + K A+ T+ GL+ T Y + A+N G
Sbjct: 527 GVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKG 583
Score = 45.2 bits (102), Expect = 0.001
Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 22/162 (13%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV----SAE 79
P IT YV T Q G+P+ ++TW + + I S KT D + A
Sbjct: 308 PKIT-YVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 366
Query: 80 ISILT----NVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
+S LT TD +Y C A+N+ + +++ L V +AP K++ V G
Sbjct: 367 VSSLTLKSIQYTD-AGEYICTASNTIGQDS--QSMYLEVQYAP---KLQGPVAVYTWEGN 420
Query: 135 EATLICDSASSNPPATLSWWRDG--IPVQNAPIFDDTTSYNT 174
+ + C+ + P AT+SW+RDG +P N + + YNT
Sbjct: 421 QVNITCE-VFAYPSATISWFRDGQLLPSSN---YSNIKIYNT 458
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 84.6 bits (200), Expect = 1e-15
Identities = 64/239 (26%), Positives = 104/239 (43%), Gaps = 12/239 (5%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
S L + DAGIY C G+ + A ++V + K+ EDAV+
Sbjct: 79 STLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIV 138
Query: 282 CTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN-G 339
C + + L I W+ KG + K V F + +YL IR K + G ++C
Sbjct: 139 CDVVSS--LPPTIIWKHKGRDVILKKDVRFIVLS-NNYLQIRGIKKTDEGTYRCEGRILA 195
Query: 340 IGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
G +D+ +IV P + N V + +N+GQ L+C + P P+ +W+K+G ++
Sbjct: 196 RGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIE 255
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + +D +S L I V +D Y C A N+ G T+ L V + P
Sbjct: 256 QEEDDEKY--IFSDD----SSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 81.0 bits (191), Expect = 2e-14
Identities = 88/357 (24%), Positives = 146/357 (40%), Gaps = 26/357 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T +WTKDG I Q I S+ S L + K+ ++D Y C A N G A
Sbjct: 241 PEPTMSWTKDGEQIEQEE--DDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA 298
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE 311
I + V I V E L+C A G+P+ I W I + T +
Sbjct: 299 TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPI--PSITWRTSTRNISSEEKTLD 356
Query: 312 PKNL------TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFV 365
+ S L ++ + + G + C +N IG Q + L V++ P++ P V
Sbjct: 357 GHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ-DSQSMYLEVQYAPKLQ-GPVAV 414
Query: 366 KSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLIN 425
+ G + C+ + P+ + +W ++G LP S+ Y K + S L +
Sbjct: 415 YTWE--GNQVNITCEVFAYPSATISWFRDGQLLP---SSNY--SNIKIYNTPSASYLEVT 467
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDG 484
+ +D+G+Y C A N +G + L P S+ ST +++ P G
Sbjct: 468 PDSENDFGNYNCTAVNRIGQESLEFILVQADTPSS-PSIDQVEPYSSTAQVQFDEPEATG 526
Query: 485 GLQSW-YRIRYRKVFDDSYKYEDVLPKHATN---FTVHGLEKNTDYIFSVMAINKIG 537
G+ Y+ +R V ++ + + K A+ T+ GL+ T Y + A+N G
Sbjct: 527 GVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKG 583
Score = 45.2 bits (102), Expect = 0.001
Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 22/162 (13%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV----SAE 79
P IT YV T Q G+P+ ++TW + + I S KT D + A
Sbjct: 308 PKIT-YVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 366
Query: 80 ISILT----NVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
+S LT TD +Y C A+N+ + +++ L V +AP K++ V G
Sbjct: 367 VSSLTLKSIQYTD-AGEYICTASNTIGQDS--QSMYLEVQYAP---KLQGPVAVYTWEGN 420
Query: 135 EATLICDSASSNPPATLSWWRDG--IPVQNAPIFDDTTSYNT 174
+ + C+ + P AT+SW+RDG +P N + + YNT
Sbjct: 421 QVNITCE-VFAYPSATISWFRDGQLLPSSN---YSNIKIYNT 458
>BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion
molecule 1 protein.
Length = 858
Score = 84.6 bits (200), Expect = 1e-15
Identities = 64/239 (26%), Positives = 104/239 (43%), Gaps = 12/239 (5%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
S L + DAGIY C G+ + A ++V + K+ EDAV+
Sbjct: 79 STLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIV 138
Query: 282 CTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN-G 339
C + + L I W+ KG + K V F + +YL IR K + G ++C
Sbjct: 139 CDVVSS--LPPTIIWKHKGRDVILKKDVRFIVLS-NNYLQIRGIKKTDEGTYRCEGRILA 195
Query: 340 IGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
G +D+ +IV P + N V + +N+GQ L+C + P P+ +W+K+G ++
Sbjct: 196 RGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIE 255
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + +D +S L I V +D Y C A N+ G T+ L V + P
Sbjct: 256 QEEDDEKY--IFSDD----SSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 74.9 bits (176), Expect = 1e-12
Identities = 90/366 (24%), Positives = 149/366 (40%), Gaps = 34/366 (9%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T +WTKDG I Q I S+ S L + K+ ++D Y C A N G A
Sbjct: 241 PEPTMSWTKDGEQIEQEE--DDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA 298
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-------------EHIKWER 298
I + V I V E L+C A G+P+ + E W R
Sbjct: 299 TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTR 358
Query: 299 --KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKP 356
K +D V ++S L ++ + + G + C +N IG Q + L V++ P
Sbjct: 359 PEKQETLDGHMVVRSHARVSS-LTLKSIQYTDAGEYICTASNTIGQ-DSQSMYLEVQYAP 416
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
++ P V + G + C+ + P+ + +W ++G LP S+ Y K +
Sbjct: 417 KLQ-GPVAVYTWE--GNQVNITCEVFAYPSATISWFRDGQLLP---SSNY--SNIKIYNT 468
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTL 476
S L + + +D+G+Y C A N +G + L P S+ ST +
Sbjct: 469 PSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSS-PSIDQVEPYSSTAQV 527
Query: 477 EW-VPGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHATN---FTVHGLEKNTDYIFSVM 531
++ P GG+ Y+ +R V ++ + + K A+ T+ GL+ T Y +
Sbjct: 528 QFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLA 587
Query: 532 AINKIG 537
A+N G
Sbjct: 588 ALNGKG 593
>BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein.
Length = 364
Score = 84.6 bits (200), Expect = 1e-15
Identities = 64/239 (26%), Positives = 104/239 (43%), Gaps = 12/239 (5%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
S L + DAGIY C G+ + A ++V + K+ EDAV+
Sbjct: 79 STLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIV 138
Query: 282 CTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN-G 339
C + + L I W+ KG + K V F + +YL IR K + G ++C
Sbjct: 139 CDVVSS--LPPTIIWKHKGRDVILKKDVRFIVLS-NNYLQIRGIKKTDEGTYRCEGRILA 195
Query: 340 IGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
G +D+ +IV P + N V + +N+GQ L+C + P P+ +W+K+G ++
Sbjct: 196 RGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIE 255
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + +D +S L I V +D Y C A N+ G T+ L V + P
Sbjct: 256 QEEDDEKY--IFSDD----SSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 49.2 bits (112), Expect = 6e-05
Identities = 47/183 (25%), Positives = 83/183 (45%), Gaps = 17/183 (9%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEA-VNSQGAA-VANISVSVHYPAGIKSVSQNVV---A 272
I+ + L + + + D G Y CE + ++G +I V V+ P I++ QN+V A
Sbjct: 167 IVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQA-RQNIVNATA 225
Query: 273 NPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS--VTFEPKNLTSYLIIRKAKSENLG 330
N + L C A G P + W + G +I+ + + + +S L I+K +
Sbjct: 226 NLGQSVTLVCDAEGFP--EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEA 283
Query: 331 NFQCVVNNGIGSATKQDVMLIVKF--KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
+ C+ N G +QD + +K KP++ N ++A + + L C+ P PS
Sbjct: 284 EYICIAENKAG---EQDATIHLKVFAKPKITYVEN--QTAMELEEQVTLTCEASGDPIPS 338
Query: 389 FTW 391
TW
Sbjct: 339 ITW 341
Score = 47.6 bits (108), Expect = 2e-04
Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 3/98 (3%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T +WTKDG I Q I S+ S L + K+ ++D Y C A N G A
Sbjct: 241 PEPTMSWTKDGEQIEQEE--DDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA 298
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPL 289
I + V I V E L+C A G+P+
Sbjct: 299 TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPI 336
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 84.6 bits (200), Expect = 1e-15
Identities = 64/239 (26%), Positives = 104/239 (43%), Gaps = 12/239 (5%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
S L + DAGIY C G+ + A ++V + K+ EDAV+
Sbjct: 160 STLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIV 219
Query: 282 CTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN-G 339
C + + L I W+ KG + K V F + +YL IR K + G ++C
Sbjct: 220 CDVVSS--LPPTIIWKHKGRDVILKKDVRFIVLS-NNYLQIRGIKKTDEGTYRCEGRILA 276
Query: 340 IGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
G +D+ +IV P + N V + +N+GQ L+C + P P+ +W+K+G ++
Sbjct: 277 RGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIE 336
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + +D +S L I V +D Y C A N+ G T+ L V + P
Sbjct: 337 QEEDDEKY--IFSDD----SSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 389
Score = 81.0 bits (191), Expect = 2e-14
Identities = 88/357 (24%), Positives = 146/357 (40%), Gaps = 26/357 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T +WTKDG I Q I S+ S L + K+ ++D Y C A N G A
Sbjct: 322 PEPTMSWTKDGEQIEQEE--DDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA 379
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE 311
I + V I V E L+C A G+P+ I W I + T +
Sbjct: 380 TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPI--PSITWRTSTRNISSEEKTLD 437
Query: 312 PKNL------TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFV 365
+ S L ++ + + G + C +N IG Q + L V++ P++ P V
Sbjct: 438 GHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ-DSQSMYLEVQYAPKLQ-GPVAV 495
Query: 366 KSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLIN 425
+ G + C+ + P+ + +W ++G LP S+ Y K + S L +
Sbjct: 496 YTWE--GNQVNITCEVFAYPSATISWFRDGQLLP---SSNY--SNIKIYNTPSASYLEVT 548
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDG 484
+ +D+G+Y C A N +G + L P S+ ST +++ P G
Sbjct: 549 PDSENDFGNYNCTAVNRIGQESLEFILVQADTPSS-PSIDQVEPYSSTAQVQFDEPEATG 607
Query: 485 GLQSW-YRIRYRKVFDDSYKYEDVLPKHATN---FTVHGLEKNTDYIFSVMAINKIG 537
G+ Y+ +R V ++ + + K A+ T+ GL+ T Y + A+N G
Sbjct: 608 GVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKG 664
Score = 45.2 bits (102), Expect = 0.001
Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 22/162 (13%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV----SAE 79
P IT YV T Q G+P+ ++TW + + I S KT D + A
Sbjct: 389 PKIT-YVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 447
Query: 80 ISILT----NVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
+S LT TD +Y C A+N+ + +++ L V +AP K++ V G
Sbjct: 448 VSSLTLKSIQYTD-AGEYICTASNTIGQDS--QSMYLEVQYAP---KLQGPVAVYTWEGN 501
Query: 135 EATLICDSASSNPPATLSWWRDG--IPVQNAPIFDDTTSYNT 174
+ + C+ + P AT+SW+RDG +P N + + YNT
Sbjct: 502 QVNITCE-VFAYPSATISWFRDGQLLPSSN---YSNIKIYNT 539
>L34774-1|AAA36387.1| 345|Homo sapiens opioid-binding cell adhesion
molecule protein.
Length = 345
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 16/220 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V P I ++S ++ N L C AIG P
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W K V+ + YL I K + G ++C N + + + V + V
Sbjct: 166 TVTWRHLSVKEGQGFVSED-----EYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 220
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + N + +VGQ G L C+ +VP F W K +L + +
Sbjct: 221 NYPPYISKAKN---TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG------LDGMR 271
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
++ S L NV+ DYG+Y C A N+LG + ++ L
Sbjct: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
Score = 54.0 bits (124), Expect = 2e-06
Identities = 56/211 (26%), Positives = 89/211 (42%), Gaps = 19/211 (9%)
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPS 194
E C + N P T R + VQ P + +S TV E + + A G P
Sbjct: 110 EGPYTCSVQTDNHPKTS---RVHLIVQVPPQIMNISSDITVN-EGSSVTLLCLAIGRPEP 165
Query: 195 ITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA-VANI 253
T TW S G +SE L ++ + R +G Y C A+N A V +
Sbjct: 166 -TVTWR-------HLSVKEGQG-FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 216
Query: 254 SVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVTFE 311
++V+YP I S ++N + + +LSC A P +AE +W ++ ++ + E
Sbjct: 217 KITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVP-MAE-FQWFKEETRLATGLDGMRIE 273
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
K S L ++ GN+ CV N +G+
Sbjct: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
>BX537377-1|CAD97619.1| 338|Homo sapiens hypothetical protein
protein.
Length = 338
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 16/220 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V P I ++S ++ N L C AIG P
Sbjct: 101 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP--EP 158
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W K V+ + YL I K + G ++C N + + + V + V
Sbjct: 159 TVTWRHLSVKEGQGFVSED-----EYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 213
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + N + +VGQ G L C+ +VP F W K +L + +
Sbjct: 214 NYPPYISKAKN---TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG------LDGMR 264
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
++ S L NV+ DYG+Y C A N+LG + ++ L
Sbjct: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
Score = 54.0 bits (124), Expect = 2e-06
Identities = 56/211 (26%), Positives = 89/211 (42%), Gaps = 19/211 (9%)
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPS 194
E C + N P T R + VQ P + +S TV E + + A G P
Sbjct: 103 EGPYTCSVQTDNHPKTS---RVHLIVQVPPQIMNISSDITVN-EGSSVTLLCLAIGRPEP 158
Query: 195 ITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA-VANI 253
T TW S G +SE L ++ + R +G Y C A+N A V +
Sbjct: 159 -TVTWR-------HLSVKEGQG-FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 209
Query: 254 SVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVTFE 311
++V+YP I S ++N + + +LSC A P +AE +W ++ ++ + E
Sbjct: 210 KITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVP-MAE-FQWFKEETRLATGLDGMRIE 266
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
K S L ++ GN+ CV N +G+
Sbjct: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 297
>BC126251-1|AAI26252.1| 345|Homo sapiens opioid binding
protein/cell adhesion molecule-like protein.
Length = 345
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 16/220 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V P I ++S ++ N L C AIG P
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W K V+ + YL I K + G ++C N + + + V + V
Sbjct: 166 TVTWRHLSVKEGQGFVSED-----EYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 220
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + N + +VGQ G L C+ +VP F W K +L + +
Sbjct: 221 NYPPYISKAKN---TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG------LDGMR 271
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
++ S L NV+ DYG+Y C A N+LG + ++ L
Sbjct: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
Score = 54.0 bits (124), Expect = 2e-06
Identities = 56/211 (26%), Positives = 89/211 (42%), Gaps = 19/211 (9%)
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPS 194
E C + N P T R + VQ P + +S TV E + + A G P
Sbjct: 110 EGPYTCSVQTDNHPKTS---RVHLIVQVPPQIMNISSDITVN-EGSSVTLLCLAIGRPEP 165
Query: 195 ITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA-VANI 253
T TW S G +SE L ++ + R +G Y C A+N A V +
Sbjct: 166 -TVTWR-------HLSVKEGQG-FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 216
Query: 254 SVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVTFE 311
++V+YP I S ++N + + +LSC A P +AE +W ++ ++ + E
Sbjct: 217 KITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVP-MAE-FQWFKEETRLATGLDGMRIE 273
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
K S L ++ GN+ CV N +G+
Sbjct: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
>BC117254-1|AAI17255.1| 345|Homo sapiens opioid binding
protein/cell adhesion molecule-like protein.
Length = 345
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 16/220 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V P I ++S ++ N L C AIG P
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W K V+ + YL I K + G ++C N + + + V + V
Sbjct: 166 TVTWRHLSVKEGQGFVSED-----EYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 220
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + N + +VGQ G L C+ +VP F W K +L + +
Sbjct: 221 NYPPYISKAKN---TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG------LDGMR 271
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
++ S L NV+ DYG+Y C A N+LG + ++ L
Sbjct: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
Score = 54.0 bits (124), Expect = 2e-06
Identities = 56/211 (26%), Positives = 89/211 (42%), Gaps = 19/211 (9%)
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPS 194
E C + N P T R + VQ P + +S TV E + + A G P
Sbjct: 110 EGPYTCSVQTDNHPKTS---RVHLIVQVPPQIMNISSDITVN-EGSSVTLLCLAIGRPEP 165
Query: 195 ITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA-VANI 253
T TW S G +SE L ++ + R +G Y C A+N A V +
Sbjct: 166 -TVTWR-------HLSVKEGQG-FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 216
Query: 254 SVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVTFE 311
++V+YP I S ++N + + +LSC A P +AE +W ++ ++ + E
Sbjct: 217 KITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVP-MAE-FQWFKEETRLATGLDGMRIE 273
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
K S L ++ GN+ CV N +G+
Sbjct: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
>BC074773-1|AAH74773.1| 345|Homo sapiens opioid binding
protein/cell adhesion molecule-like protein.
Length = 345
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 16/220 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V P I ++S ++ N L C AIG P
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W K V+ + YL I K + G ++C N + + + V + V
Sbjct: 166 TVTWRHLSVKEGQGFVSED-----EYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 220
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + N + +VGQ G L C+ +VP F W K +L + +
Sbjct: 221 NYPPYISKAKN---TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG------LDGMR 271
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
++ S L NV+ DYG+Y C A N+LG + ++ L
Sbjct: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
Score = 54.0 bits (124), Expect = 2e-06
Identities = 56/211 (26%), Positives = 89/211 (42%), Gaps = 19/211 (9%)
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPS 194
E C + N P T R + VQ P + +S TV E + + A G P
Sbjct: 110 EGPYTCSVQTDNHPKTS---RVHLIVQVPPQIMNISSDITVN-EGSSVTLLCLAIGRPEP 165
Query: 195 ITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA-VANI 253
T TW S G +SE L ++ + R +G Y C A+N A V +
Sbjct: 166 -TVTWR-------HLSVKEGQG-FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 216
Query: 254 SVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVTFE 311
++V+YP I S ++N + + +LSC A P +AE +W ++ ++ + E
Sbjct: 217 KITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVP-MAE-FQWFKEETRLATGLDGMRIE 273
Query: 312 PKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
K S L ++ GN+ CV N +G+
Sbjct: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 84.2 bits (199), Expect = 2e-15
Identities = 104/408 (25%), Positives = 168/408 (41%), Gaps = 46/408 (11%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N V + + P+ G+PP W K+ + Y +D + G + +
Sbjct: 266 NQVVLADAPVTFLCEVKGDPPP-RLRWRKEDGELPTGRYEIRSDHSLWIGHV------SA 318
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
D G YTC A NS G A A+ S+SVH P + + Q+ +A P E C GNP A
Sbjct: 319 EDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPA- 377
Query: 293 HIKWERKGYKIDP-KSVTFEPKNLTS-----YLIIRKAKSENLGNFQCVVNNGIGSATKQ 346
I W+++G ++ S + +P S L I + + G + C + GS +
Sbjct: 378 -IFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAGSILAK 436
Query: 347 DVMLIVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
+L +K P ++ +N +G L C+ P PS W K+G L +
Sbjct: 437 -ALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDD 495
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT--VKL-------- 452
+F + T L I NV D G Y C A++ G +T + +K+
Sbjct: 496 -----LQFKTMANGT----LYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSP 546
Query: 453 ----DVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGG--LQSWYRIRYRKVFDDSYKYED 506
+ +S P VT +T +++TL W P G + S+ + ++++
Sbjct: 547 DPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVA 606
Query: 507 VLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSS 554
+ T+ TV GL+ NT Y+F V A+ G S+ P T SS
Sbjct: 607 DGVQLETH-TVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQDSS 653
Score = 69.7 bits (163), Expect = 4e-11
Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 29/293 (9%)
Query: 180 EPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT-----RH 233
EP + RA+G P P+I W K+G + R++ L ++ R
Sbjct: 79 EPATLPCRAEGRPRPNIE--WYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARP 136
Query: 234 DAGIYTCEAVNSQGAAVA-NISVSVH-YPAGIKSVSQNVVANPNEDAVLSCT-AIGNPLL 290
D G+YTC A N GAA + N S+ V + NVV E AVL C G+P
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHP-- 194
Query: 291 AEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
+ W + G ++ + + L++ + G + CV +N G +
Sbjct: 195 EPSVSWRKDGARLKEEEGRITIRG--GKLMMSHTLKSDAGMYVCVASNMAGERESAAAEV 252
Query: 351 IVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
+V +P P V +C+ K P P W K +LP +Y
Sbjct: 253 MVLERPSFLRRP--VNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTG---RYEI-- 305
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
++DH L I +V+ D G+Y C A N +G + + L V P Q+V+
Sbjct: 306 -RSDH-----SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV-HVPPQLVT 351
Score = 67.7 bits (158), Expect = 2e-10
Identities = 79/318 (24%), Positives = 132/318 (41%), Gaps = 30/318 (9%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N V EP ++ P + +W KDG + + RI G L M+ +
Sbjct: 174 NVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEE-----GRITIRGGKLMMSHTLK 228
Query: 233 HDAGIYTCEAVNSQG---AAVANISVSVHYPAGI-KSVSQNVVANPNEDAVLSCTAIGNP 288
DAG+Y C A N G +A A + V + P+ + + V+Q V+A + C G+P
Sbjct: 229 SDAGMYVCVASNMAGERESAAAEVMV-LERPSFLRRPVNQVVLA--DAPVTFLCEVKGDP 285
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
++W ++ ++ + +E ++ S L I +E+ G + CV N +G A +
Sbjct: 286 --PPRLRWRKEDGEL--PTGRYEIRSDHS-LWIGHVSAEDEGTYTCVAENSVGRA-EASG 339
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG--VKLPVNTSTKY 406
L V P++ T P +A G+ C+ K P P+ W K G V L + S +
Sbjct: 340 SLSVHVPPQLVTQPQDQMAAP--GESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQP 397
Query: 407 FAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP-DQVVSLT 465
F ++ L I V D G Y C A + G L++ A D + +
Sbjct: 398 TGRF----SVSPRGQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDGLPPVI 453
Query: 466 VTNVTHSTVTL---EWVP 480
+ + T+ L W+P
Sbjct: 454 LQGPANQTLVLGSSVWLP 471
Score = 33.9 bits (74), Expect = 2.4
Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 5/93 (5%)
Query: 356 PEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
PE D P V+ ++ G+ L C+ + P P+ W KNG ++
Sbjct: 59 PE-DAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLL 117
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++ A D G Y C ARN LG
Sbjct: 118 LPSGALFFPRIVHGRRARPDEGVYTCVARNYLG 150
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 83.4 bits (197), Expect = 3e-15
Identities = 64/239 (26%), Positives = 104/239 (43%), Gaps = 12/239 (5%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
S L + DAGIY C G+ + A ++V + K+ EDAV+
Sbjct: 79 STLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIV 138
Query: 282 CTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN-G 339
C + + L I W+ KG + K V F + +YL IR K + G ++C
Sbjct: 139 CDVVSS--LPPTIIWKHKGRDVILKKDVRFIVLS-NNYLQIRGIKKTDEGTYRCEGRILA 195
Query: 340 IGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
G +D+ +IV P + N V + +N+GQ L+C + P P+ +W+K+G ++
Sbjct: 196 RGEINFKDIQVIVNVPPTIRARQNIVNATANLGQSVTLVCDAERFPEPTMSWTKDGEQIE 255
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + +D +S L I V +D Y C A N+ G T+ L V + P
Sbjct: 256 QEEDDEKY--IFSDD----SSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 83.4 bits (197), Expect = 3e-15
Identities = 91/360 (25%), Positives = 150/360 (41%), Gaps = 32/360 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T +WTKDG I Q I S+ S L + K+ ++D Y C A N G A
Sbjct: 241 PEPTMSWTKDGEQIEQEE--DDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA 298
Query: 252 NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE 311
I + V I V E L+C A G+P+ I W I + T +
Sbjct: 299 TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPI--PSITWRTSTRNISSEEKTLD 356
Query: 312 PKNL------TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFV 365
+ S L ++ + + G + C +N IG Q + L V++ P++ P V
Sbjct: 357 GHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ-DSQSMYLEVQYAPKLQ-GPVAV 414
Query: 366 KSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLIN 425
+ G + C+ + P+ + +W ++G LP S+ Y K + S L +
Sbjct: 415 YTWE--GNQVNITCEVFAYPSATISWFRDGQLLP---SSNY--SNIKIYNTPSASYLEVT 467
Query: 426 NVATSDYGSYECGARNELG---FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPG 481
+ +D+G+Y C A N +G F V+ D S+P S+ ST +++ P
Sbjct: 468 PDSENDFGNYNCTAVNRIGQESFEFILVQADTPSSP----SIDQVEPYSSTAQVQFDEPE 523
Query: 482 FDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHATN---FTVHGLEKNTDYIFSVMAINKIG 537
GG+ Y+ +R V ++ + + K A+ T+ GL+ T Y + A+N G
Sbjct: 524 ATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKG 583
Score = 66.1 bits (154), Expect = 5e-10
Identities = 79/359 (22%), Positives = 152/359 (42%), Gaps = 24/359 (6%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEA-VNSQGAA-VANISVSVHYPAGIKSVSQNVV---A 272
I+ + L + + + D G Y CE + ++G +I V V+ P I++ QN+V A
Sbjct: 167 IVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIRA-RQNIVNATA 225
Query: 273 NPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS--VTFEPKNLTSYLIIRKAKSENLG 330
N + L C A P + W + G +I+ + + + +S L I+K +
Sbjct: 226 NLGQSVTLVCDAERFP--EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEA 283
Query: 331 NFQCVVNNGIGSATKQDVMLIVKF--KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
+ C+ N G +QD + +K KP++ N ++A + + L C+ P PS
Sbjct: 284 EYICIAENKAG---EQDATIHLKVFAKPKITYVEN--QTAMELEEQVTLTCEASGDPIPS 338
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTT 448
TW + + T H +S L + ++ +D G Y C A N +G +
Sbjct: 339 ITWRTSTRNISSEEKT-LDGHMVVRSHARVSS-LTLKSIQYTDAGEYICTASNTIGQDSQ 396
Query: 449 TVKLDVTSAP--DQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYED 506
++ L+V AP V++ +T E V + SW+R + + +Y
Sbjct: 397 SMYLEVQYAPKLQGPVAVYTWEGNQVNITCE-VFAYPSATISWFRDG-QLLPSSNYSNIK 454
Query: 507 VLPKHATNFTVHGLEKNTDY-IFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVST 564
+ + ++ + D+ ++ A+N+IGQ + +A T +S + ++ S+
Sbjct: 455 IYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESFEFILVQADTPSSPSIDQVEPYSS 513
Score = 45.2 bits (102), Expect = 0.001
Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 22/162 (13%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAV----SAE 79
P IT YV T Q G+P+ ++TW + + I S KT D + A
Sbjct: 308 PKIT-YVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 366
Query: 80 ISILT----NVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
+S LT TD +Y C A+N+ + +++ L V +AP K++ V G
Sbjct: 367 VSSLTLKSIQYTD-AGEYICTASNTIGQDS--QSMYLEVQYAP---KLQGPVAVYTWEGN 420
Query: 135 EATLICDSASSNPPATLSWWRDG--IPVQNAPIFDDTTSYNT 174
+ + C+ + P AT+SW+RDG +P N + + YNT
Sbjct: 421 QVNITCE-VFAYPSATISWFRDGQLLPSSN---YSNIKIYNT 458
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 83.4 bits (197), Expect = 3e-15
Identities = 78/271 (28%), Positives = 119/271 (43%), Gaps = 26/271 (9%)
Query: 188 ADGNPPSITYTWTKD-GLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G+P + TWT+D GL + S R ++ S L + +T+ D G +TC A NS
Sbjct: 353 ATGHPHPLI-TWTRDNGLELDGS-------RHVATSSGLYLQNITQRDHGRFTCHANNSH 404
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G A ++ V P ++ V C A GNP I W + G ++
Sbjct: 405 GTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNP--PPVIVWTKTGGQL--- 459
Query: 307 SVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFV 365
V + L+S L I +A + G ++C + +G K V L VK K +
Sbjct: 460 PVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLG-VKKVSVQLTVKPKALAVFTQLPQ 518
Query: 366 KSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLIN 425
++ VG+ + C + P P TW+K GV++ + +FH +D T T I
Sbjct: 519 DTSVEVGKNINISCHAQGEPQPIITWNKEGVQITES------GKFHVDDEGTLT----IY 568
Query: 426 NVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ D G YEC ARN G + T + L VT+
Sbjct: 569 DAGFPDQGRYECVARNSFGLAVTNMFLTVTA 599
Score = 65.3 bits (152), Expect = 9e-10
Identities = 65/260 (25%), Positives = 96/260 (36%), Gaps = 26/260 (10%)
Query: 233 HDAGIYTCEAVNS-QGAAVANISVSVH--YPAGIKSVSQNVVANPNEDAVLSCTAIGNPL 289
H TCE G AVA+++V I Q+V +C A GNP
Sbjct: 203 HTQAAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNP- 261
Query: 290 LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVM 349
I W + +D + T L+IR + + G +QC+ N G A Q M
Sbjct: 262 -KPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAM 320
Query: 350 LIVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSK-NGVKLPVNTST 404
L P P+FV + +G L C P P TW++ NG++L +
Sbjct: 321 LRYSSLP---AKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSR-- 375
Query: 405 KYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL 464
H+ +S L + N+ D+G + C A N G + + AP Q
Sbjct: 376 ----------HVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANI-IVQAPPQFTVT 424
Query: 465 TVTNVTHSTVTLEWVPGFDG 484
V +EW+ DG
Sbjct: 425 PKDQVVLEEHAVEWLCEADG 444
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 83.4 bits (197), Expect = 3e-15
Identities = 104/408 (25%), Positives = 168/408 (41%), Gaps = 46/408 (11%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N V + + P+ G+PP W K+ + Y +D + G + +
Sbjct: 266 NQVVLADAPVTFLCEVKGDPPP-RLRWRKEDGELPTGRYEIRSDHSLWIGHV------SA 318
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
D G YTC A NS G A A+ S+SVH P + + Q+ +A P E C GNP A
Sbjct: 319 EDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPA- 377
Query: 293 HIKWERKGYKIDP-KSVTFEPKNLTS-----YLIIRKAKSENLGNFQCVVNNGIGSATKQ 346
I W+++G ++ S + +P S L I + + G + C + GS +
Sbjct: 378 -IFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAK 436
Query: 347 DVMLIVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNT 402
+L +K P ++ +N +G L C+ P PS W K+G L +
Sbjct: 437 -ALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDD 495
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT--VKL-------- 452
+F + T L I NV D G Y C A++ G +T + +K+
Sbjct: 496 -----LQFKTMANGT----LYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSP 546
Query: 453 ----DVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGG--LQSWYRIRYRKVFDDSYKYED 506
+ +S P VT +T +++TL W P G + S+ + ++++
Sbjct: 547 DPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVA 606
Query: 507 VLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSS 554
+ T+ TV GL+ NT Y+F V A+ G S+ P T SS
Sbjct: 607 DGVQLETH-TVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQDSS 653
Score = 69.7 bits (163), Expect = 4e-11
Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 29/293 (9%)
Query: 180 EPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT-----RH 233
EP + RA+G P P+I W K+G + R++ L ++ R
Sbjct: 79 EPATLPCRAEGRPRPNIE--WYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARP 136
Query: 234 DAGIYTCEAVNSQGAAVA-NISVSVH-YPAGIKSVSQNVVANPNEDAVLSCT-AIGNPLL 290
D G+YTC A N GAA + N S+ V + NVV E AVL C G+P
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHP-- 194
Query: 291 AEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
+ W + G ++ + + L++ + G + CV +N G +
Sbjct: 195 EPSVSWRKDGARLKEEEGRITIRG--GKLMMSHTLKSDAGMYVCVASNMAGERESAAAEV 252
Query: 351 IVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
+V +P P V +C+ K P P W K +LP +Y
Sbjct: 253 MVLERPSFLRRP--VNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTG---RYEI-- 305
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
++DH L I +V+ D G+Y C A N +G + + L V P Q+V+
Sbjct: 306 -RSDH-----SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV-HVPPQLVT 351
Score = 67.7 bits (158), Expect = 2e-10
Identities = 79/318 (24%), Positives = 132/318 (41%), Gaps = 30/318 (9%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N V EP ++ P + +W KDG + + RI G L M+ +
Sbjct: 174 NVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEE-----GRITIRGGKLMMSHTLK 228
Query: 233 HDAGIYTCEAVNSQG---AAVANISVSVHYPAGI-KSVSQNVVANPNEDAVLSCTAIGNP 288
DAG+Y C A N G +A A + V + P+ + + V+Q V+A + C G+P
Sbjct: 229 SDAGMYVCVASNMAGERESAAAEVMV-LERPSFLRRPVNQVVLA--DAPVTFLCEVKGDP 285
Query: 289 LLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
++W ++ ++ + +E ++ S L I +E+ G + CV N +G A +
Sbjct: 286 --PPRLRWRKEDGEL--PTGRYEIRSDHS-LWIGHVSAEDEGTYTCVAENSVGRA-EASG 339
Query: 349 MLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG--VKLPVNTSTKY 406
L V P++ T P +A G+ C+ K P P+ W K G V L + S +
Sbjct: 340 SLSVHVPPQLVTQPQDQMAAP--GESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQP 397
Query: 407 FAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP-DQVVSLT 465
F ++ L I V D G Y C A + G L++ A D + +
Sbjct: 398 TGRF----SVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVI 453
Query: 466 VTNVTHSTVTL---EWVP 480
+ + T+ L W+P
Sbjct: 454 LQGPANQTLVLGSSVWLP 471
Score = 33.9 bits (74), Expect = 2.4
Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 5/93 (5%)
Query: 356 PEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
PE D P V+ ++ G+ L C+ + P P+ W KNG ++
Sbjct: 59 PE-DAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLL 117
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELG 444
+ ++ A D G Y C ARN LG
Sbjct: 118 LPSGALFFPRIVHGRRARPDEGVYTCVARNYLG 150
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 83.4 bits (197), Expect = 3e-15
Identities = 92/364 (25%), Positives = 147/364 (40%), Gaps = 26/364 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P T W KD + I S + ++++ G L + KL D+GI+ C A N G +
Sbjct: 414 PLPTLQWYKDAISI--SRLQNPRYKVLASGG-LRIQKLRPEDSGIFQCFASNEGGEIQTH 470
Query: 253 ISVSVHYPAGIKSVSQ-NVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE 311
+ V A + + + A+L C G P A I W+R+ + + SV
Sbjct: 471 TYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPA--ITWKRENHILASGSVRIP 528
Query: 312 PKNL--TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
L + L I ++ GN+ C N GS + + + + V
Sbjct: 529 RFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIK- 587
Query: 370 NVGQVGRLMCKCKSVPAPS--FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNV 427
G L C P S + W K+ V L +++++ E + LLI+
Sbjct: 588 --GTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGS--------LLISQT 637
Query: 428 ATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVT-NVTHS-TVTLEWVPGFDGG 485
+ D G Y C +E G + +L+V P +L V+ N +HS V L WV FDG
Sbjct: 638 WSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGN 697
Query: 486 LQSWYRIRYRKVFDDSYK--YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRP 543
Y I +K +V P+ T TV GL Y F V A+N++G+ +Y
Sbjct: 698 SPILYYIVELSENSSPWKVHLSNVGPE-MTGVTVSGLTPARTYQFRVCAVNEVGRGQYSA 756
Query: 544 DDTK 547
+ ++
Sbjct: 757 ETSR 760
Score = 56.4 bits (130), Expect = 4e-07
Identities = 88/420 (20%), Positives = 160/420 (38%), Gaps = 22/420 (5%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISE 221
AP+F TV + I+ G P P+IT W ++ + S ++
Sbjct: 479 APVFTQRPVDTTV-TDGMTAILRCEVSGAPKPAIT--WKRENHILASGSVRIPRFMLLES 535
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
G L + + DAG YTC A N++G+ A+ +++V I ++ V A L
Sbjct: 536 GG-LQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLH 594
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C A +P ++ W++ + P S + L+I + S ++G++ C + + G
Sbjct: 595 CGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGG 654
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
+ ++ + ++ E+ SP + + N ++ + V+L N
Sbjct: 655 NDSRMARLEVI----ELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSEN 710
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG---FSTTTVKLDVTSAP 458
+S + N T V + Y C A NE+G +S T +L + P
Sbjct: 711 SSP--WKVHLSNVGPEMTGVTVSGLTPARTYQFRVC-AVNEVGRGQYSAETSRLMLPEEP 767
Query: 459 DQV--VSLTVTNVTHSTVTLEWVPGFD---GGLQSWYRIRYRKV-FDDSYKYEDVLPKHA 512
++ + T+ ++ ++W P + G+ Y +RYR Y+ ++
Sbjct: 768 PSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEV 827
Query: 513 TNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDI 572
V L T Y V A N G + T+ TL V TE V + I
Sbjct: 828 NYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTE-YTLQGVPTAPPQNVQTEAVNSTTI 886
Score = 54.4 bits (125), Expect = 2e-06
Identities = 74/320 (23%), Positives = 126/320 (39%), Gaps = 36/320 (11%)
Query: 166 FDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSML 225
F DT TV + I+++ + P TW ++G I S N I+ + L
Sbjct: 193 FMDTDQRKTVS-QGRAAILNLLPITSYPRPQVTWFREGHKIIPS-----NRIAITLENQL 246
Query: 226 NMTKLTRHDAGIYTCEAVNSQGAAVAN---ISVSVHYPAGI-KSVSQNVVANPNEDAV-- 279
+ T DAG Y +AVN + I +S+ G ++++ +V P +V
Sbjct: 247 VILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVA 306
Query: 280 ------LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQ 333
L C A P+ + W+R G +I +F +L I S + G +
Sbjct: 307 GSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSFG-----RHLTISNPTSADTGPYV 361
Query: 334 C-VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWS 392
C G + + +P T+ + ++ V + + C+ VP P+ W
Sbjct: 362 CEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWY 421
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ + + + +Y + + L I + D G ++C A NE G T L
Sbjct: 422 KDAISISRLQNPRY--------KVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYL 473
Query: 453 DVTS-AP---DQVVSLTVTN 468
DVT+ AP + V TVT+
Sbjct: 474 DVTNIAPVFTQRPVDTTVTD 493
Score = 52.4 bits (120), Expect = 6e-06
Identities = 70/289 (24%), Positives = 110/289 (38%), Gaps = 39/289 (13%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP F + +E L+++ A+G+ P + + W +D +T +YSS II
Sbjct: 103 APYFKTEPGLPQIHLEGNRLVLTCLAEGSWP-LEFKWMRDDSELT--TYSSEYKYIIPS- 158
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANIS-VSVHYPAGIKSVSQNVVANPNEDAVLS 281
L + DAG Y C N GA + S V V Y Q + A+L+
Sbjct: 159 -------LQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILN 211
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
I + W R+G+KI P + L + L+I + + G + N
Sbjct: 212 LLPI-TSYPRPQVTWFREGHKIIPSNRI--AITLENQLVILATTTSDAGAYYVQAVNEKN 268
Query: 342 SATKQDVMLIVKFKPEMDT----SPNFVKSASNVGQVG-----RLMCKCKSVPAP--SFT 390
K + + ++ T +P V N V L C + P S T
Sbjct: 269 GENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVT 328
Query: 391 WSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGA 439
W +NGV++ T F + H+T I+N ++D G Y C A
Sbjct: 329 WKRNGVRI-----TSGLHSFGR--HLT------ISNPTSADTGPYVCEA 364
Score = 41.5 bits (93), Expect = 0.012
Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 2/97 (2%)
Query: 457 APDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYK-YEDVLPKHATN 514
AP + + + VT ++ L+WVPG DG ++ ++ R++ ++ Y + AT
Sbjct: 1478 APPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATA 1537
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTL 551
V L T Y + A N IG S + + TTL
Sbjct: 1538 CVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTL 1574
Score = 36.3 bits (80), Expect = 0.45
Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDG--GLQSWYRIRYRKVFDDSYK----YED 506
D+ AP +V ++N++ + TL++ PG+DG + W D + YE+
Sbjct: 1068 DLPGAPSNLV---ISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEE 1124
Query: 507 VLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTL 551
A + L T Y F + +N +G S Y P TL
Sbjct: 1125 ENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTL 1169
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1b protein.
Length = 1842
Score = 83.4 bits (197), Expect = 3e-15
Identities = 78/315 (24%), Positives = 124/315 (39%), Gaps = 16/315 (5%)
Query: 179 NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGI 237
N+ L + A G P P+I W KDG P+ S R + L ++ L D+G
Sbjct: 29 NDSLQLPCTAPGYPIPAIR--WLKDGRPLPADS------RWTKRITGLTISDLRTEDSGT 80
Query: 238 YTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
Y CE N+ G+A A + V P + + + +LSC G+P I+W
Sbjct: 81 YICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFT--IRWY 138
Query: 298 RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPE 357
R + P L+I A+ + G +QC + T QD +I
Sbjct: 139 RNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGT 196
Query: 358 MDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
+F + N G+ LMC K P P+ TW+ + + V + ++ +D T
Sbjct: 197 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHRTNQYTMSDGTT 255
Query: 418 YTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT-HSTVTL 476
S + + D G Y C ARN +G + +++V P +T V T+
Sbjct: 256 -ISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLIN 314
Query: 477 EWVPGFDGGLQSWYR 491
V G+ WY+
Sbjct: 315 CRVIGYPYYSIKWYK 329
Score = 77.8 bits (183), Expect = 1e-13
Identities = 85/372 (22%), Positives = 146/372 (39%), Gaps = 16/372 (4%)
Query: 186 VRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNS 245
V + G+ P I TW KDG I S + + ++ L +H+ G TC A N+
Sbjct: 407 VVSSGDMP-IRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSL-KHN-GNDTCIASNA 463
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP---LLAEHIKWERKGYK 302
+ V P N + VL+C+ G P ++ +H K +
Sbjct: 464 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 523
Query: 303 IDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
P +T + L S L+IR E++G + C +NG+G+ + + L VK + +
Sbjct: 524 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSH 583
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
PN + + G L C + W K + + +Y A K++ S
Sbjct: 584 PN--TTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRY-AIATKDNGDEVVST 640
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L + D + C A N G ++L V PD L + V ++ L W
Sbjct: 641 LKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDP-PELEIREVKARSMNLRWTQR 699
Query: 482 FDG-GLQSWYRIRYRKVFDDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
FDG + + + I Y+ DS+ ++ + + L + Y + + NKIG
Sbjct: 700 FDGNSIITGFDIEYKNK-SDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIG 758
Query: 538 QSKYRPDDTKAT 549
+S+ + T +T
Sbjct: 759 RSEPSKELTIST 770
Score = 72.5 bits (170), Expect = 6e-12
Identities = 52/167 (31%), Positives = 77/167 (46%), Gaps = 11/167 (6%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
RL C PAP+ W+K+ + S H N LL+ V D G Y
Sbjct: 1097 RLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN------GTLLLRAVKAEDSGYY 1150
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRY 494
C A N GF T V L V PDQ LTV+ + S++TL W+PG +GG + ++Y
Sbjct: 1151 TCTATNTGGFDTIIVNLLVQVPPDQ-PRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1209
Query: 495 RKVFDDSYKYEDV-LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
D+S +++DV + +F + L+ T Y + A N +G +
Sbjct: 1210 S--VDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1254
Score = 50.0 bits (114), Expect = 3e-05
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 5/124 (4%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQYRCE 96
G+ L+C TG +P T+ W++N + + + + +S E ++T+ + Y+C
Sbjct: 118 GSTVILSCALTG-SPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 176
Query: 97 ATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
AT A F + L P V +E V+ PG + +L+C +A PP T++W D
Sbjct: 177 ATRKAQTAQDFAIIALE-DGTPRIVSSFSE-KVVNPGEQFSLMC-AAKGAPPPTVTWALD 233
Query: 157 GIPV 160
P+
Sbjct: 234 DEPI 237
Score = 43.2 bits (97), Expect = 0.004
Identities = 35/145 (24%), Positives = 64/145 (44%), Gaps = 15/145 (10%)
Query: 42 KLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
+L C + G P+ + W K+ + + + ++ T + IS L T++ Y CE TN+
Sbjct: 33 QLPCTAPG-YPIPAIRWLKDGRPLPADSRWTKRITGLTISDLR--TEDSGTYICEVTNT- 88
Query: 102 TEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSA-SSNPPATLSWWRDGIPV 160
+ + + V P LK GI +T+I A + +P T+ W+R
Sbjct: 89 ----FGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYR----- 139
Query: 161 QNAPIFDDTTSYNTVGIENEPLIIS 185
N + + + G+ NE L+I+
Sbjct: 140 -NTELVLPDEAISIRGLSNETLLIT 163
Score = 33.5 bits (73), Expect = 3.2
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 242 AVNSQGAAVANISVSVH----YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
AV S G ++ V++ PA I S V +D L C ++G+P A +KW
Sbjct: 1056 AVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP--APAVKWT 1113
Query: 298 RKGYKIDPKSVTFEPKNL---TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
K + V+ + L L++R K+E+ G + C N G V L+V+
Sbjct: 1114 -KDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATN-TGGFDTIIVNLLVQV 1171
Query: 355 KPEMDTSPNFVKSASNV 371
P+ SAS++
Sbjct: 1172 PPDQPRLTVSKTSASSI 1188
Score = 33.5 bits (73), Expect = 3.2
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P+ WTKD G+ I + G++L + + D+G YTC A N+ G
Sbjct: 1106 PAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLL-LRAVKAEDSGYYTCTATNTGGFDTII 1164
Query: 253 ISVSVHYP 260
+++ V P
Sbjct: 1165 VNLLVQVP 1172
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 83.0 bits (196), Expect = 4e-15
Identities = 82/298 (27%), Positives = 119/298 (39%), Gaps = 25/298 (8%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEG 222
AP+ + S V IE + L + P W K+ + Q+ Y + + S+G
Sbjct: 230 APLIGISPSVANV-IEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYIT----VRSDG 284
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSC 282
S L++ ++ D G YTC A N G SV VH I+ Q + L C
Sbjct: 285 S-LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPC 343
Query: 283 TAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
A GNP + W +KG I S F S ++ E+ G + C N G
Sbjct: 344 KASGNP--KPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNTAGY 400
Query: 343 ATKQDVMLIVKFKPEMD------TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
A K+ V L V +P + + V+ + G+ L C+ KS+P P TW+K
Sbjct: 401 A-KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK--- 456
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
T+ + F + + I TSD G Y C A N G T VKL+V
Sbjct: 457 ------ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 508
Score = 66.1 bits (154), Expect = 5e-10
Identities = 64/239 (26%), Positives = 102/239 (42%), Gaps = 15/239 (6%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
DAGIY C A NS G N ++ + V ++ + V+ C G P
Sbjct: 16 DAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIP--PPQ 73
Query: 294 IKWERKGYKIDPKS-VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+KW + ++ P + + +P L L I++ + + G++ CV N G AT + + L V
Sbjct: 74 VKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDYTCVAINEAGRATGK-ITLDV 130
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P P V + +G L C + P P+ W + +P+ + + +
Sbjct: 131 GSPPVFIQEPADV--SMEIGSNVTLPCYVQGYPEPTIKWRRLD-NMPIFSRPFSVSSISQ 187
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELG--FSTTTVKLDVTSAPDQVVSLTVTNV 469
T L I N+ SD G+Y C A N+ G S TTV + AP +S +V NV
Sbjct: 188 ----LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANV 242
Score = 60.1 bits (139), Expect = 3e-08
Identities = 65/271 (23%), Positives = 109/271 (40%), Gaps = 23/271 (8%)
Query: 193 PSITYTWTK-DGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T W + D +PI +S + + G++ + L D G Y CEA N G +
Sbjct: 161 PEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF-ILNLWASDKGTYICEAENQFGKIQS 219
Query: 252 NISVSVH-YPAGIKSVSQNVV-ANPNEDAVLSCTAI-GNPLLAEHIKW-ERKGYKIDPKS 307
+V+V A + +S +V + L CT + GNP+ +W + +
Sbjct: 220 ETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPER--RWIKNSAMLLQNPY 277
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKS 367
+T L I + + ++ G + CV +N G+ K ++V P + + +
Sbjct: 278 ITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT-TSVVVHVLPTIQHGQQILST 333
Query: 368 ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNV 427
+ L CK P PS WSK G +L +S K+ A + L + +
Sbjct: 334 IEGIPVT--LPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGS--------LYVVSP 382
Query: 428 ATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ G Y C A N G++ V+L V P
Sbjct: 383 GGEESGEYVCTATNTAGYAKRKVQLTVYVRP 413
Score = 54.8 bits (126), Expect = 1e-06
Identities = 71/285 (24%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEA 242
++ + G PP W K L + S++ + + +L + + DAG YTC A
Sbjct: 61 VMECKTSGIPPP-QVKWFKGDLELRPSTFLIIDPLL----GLLKIQETQDLDAGDYTCVA 115
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
+N G A I++ V P +V + L C G P IKW R
Sbjct: 116 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNM 173
Query: 303 ---IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF-KPEM 358
P SV+ + T L I + + G + C N G + + + P +
Sbjct: 174 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLI 233
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSV---PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
SP S +NV + +L C + P P W KN L +N +
Sbjct: 234 GISP----SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML------------LQNPY 277
Query: 416 ITYTS--VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
IT S L I V D G Y C A N G + T + V P
Sbjct: 278 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 322
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 15/170 (8%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTL---------AAGTVQKLACISTGGNPLAT 55
KD+GI+ C+ ++ + Y+ L A G + + C T G P
Sbjct: 15 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMEC-KTSGIPPPQ 73
Query: 56 LTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
+ WFK D ++ +T + + I + Y C A N A +TL+V
Sbjct: 74 VKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT--GKITLDVG 131
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWR-DGIPVQNAP 164
P ++ A+ ++ G TL C P T+ W R D +P+ + P
Sbjct: 132 SPPVFIQEPADVS-MEIGSNVTLPC-YVQGYPEPTIKWRRLDNMPIFSRP 179
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 23 APMITGYVPGTT-LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP+I G P + G L C GNP+ W KN + T ++ +
Sbjct: 230 APLI-GISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS-DGSLH 287
Query: 82 ILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICD 141
I + +Y C A+N A +T ++ VH P + ++ GI TL C
Sbjct: 288 IERVQLQDGGEYTCVASNVAGTNN--KTTSVVVHVLPTIQHGQQILSTIE-GIPVTLPC- 343
Query: 142 SASSNPPATLSWWRDG 157
AS NP ++ W + G
Sbjct: 344 KASGNPKPSVIWSKKG 359
Score = 35.1 bits (77), Expect = 1.0
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 43 LACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTDNQAQYRCEATNSAT 102
L C GNP ++ W K + I +++ + +++ + +Y C ATN+A
Sbjct: 341 LPC-KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 399
Query: 103 EIPLFETVTLNVHFAPEAVKVRAEPDVLKP-------GIEATLICDSASSNPPATLSWWR 155
V L V+ P + KP G E TL C+ S PP ++W +
Sbjct: 400 YAK--RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE-VKSLPPPIITWAK 456
Query: 156 D 156
+
Sbjct: 457 E 457
Score = 32.3 bits (70), Expect = 7.3
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 5/82 (6%)
Query: 177 IENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAG 236
+ E + + PP I TW K+ I S S + GSM +T+ D+G
Sbjct: 433 LAGEEVTLPCEVKSLPPPII-TWAKETQLI---SPFSPRHTFLPSGSM-KITETRTSDSG 487
Query: 237 IYTCEAVNSQGAAVANISVSVH 258
+Y C A N G + ++VH
Sbjct: 488 MYLCVATNIAGNVTQAVKLNVH 509
>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 82.6 bits (195), Expect = 5e-15
Identities = 96/385 (24%), Positives = 161/385 (41%), Gaps = 34/385 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 360 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 416
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 417 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 474
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 475 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 529
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 530 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 580
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 581 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 640
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 641 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 699
Query: 541 YRPDDTKATTLTSSEVGELSTVSTE 565
P T +T E + V +
Sbjct: 700 --PSPVSETVVTPEAAPEKNPVDVK 722
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 243 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 295
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 296 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 355
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 356 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 413
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 414 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 470
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 471 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 522
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 523 GPRSTIEKKGSRVTFTCQASFDPSLQ 548
Score = 44.0 bits (99), Expect = 0.002
Identities = 73/322 (22%), Positives = 122/322 (37%), Gaps = 34/322 (10%)
Query: 156 DGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSG 214
+G V P+ + + V + + + A G P + + WT+DG+ +
Sbjct: 27 EGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKP-EVQFRWTRDGVHFKPKEELGVT 85
Query: 215 NDRIISEGSML---NMTKLTRHDAGIYTCEAVNSQGAAVAN-ISVSVH-YPAGIKSVSQN 269
+ GS N + + GIY C A N G A+++ I + P K +
Sbjct: 86 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 145
Query: 270 VVANPNEDAVLSCT--AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V E VL C PL + + K D + + NL ++ S+
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVL---TSD 202
Query: 328 NLGNFQCVVNNGIGSAT---KQDVMLIVKFKPEM-DTSPNFV---KSASNV----GQVGR 376
N ++ C + G+ T K+ + L VK M D P + S+S++ GQ
Sbjct: 203 NHSDYICHAHFP-GTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLV 261
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C + P P+ W + +P + T ++N + L + V D G Y
Sbjct: 262 LECIAEGFPTPTIKWLRPSGPMPADRVT------YQN----HNKTLQLLKVGEEDDGEYR 311
Query: 437 CGARNELGFSTTTVKLDVTSAP 458
C A N LG + + V +AP
Sbjct: 312 CLAENSLGSARHAYYVTVEAAP 333
>X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1
protein.
Length = 824
Score = 82.6 bits (195), Expect = 5e-15
Identities = 96/385 (24%), Positives = 161/385 (41%), Gaps = 34/385 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 8 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 64
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 65 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 122
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 123 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 177
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 178 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 228
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 229 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 288
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 289 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 347
Query: 541 YRPDDTKATTLTSSEVGELSTVSTE 565
P T +T E + V +
Sbjct: 348 --PSPVSETVVTPEAAPEKNPVDVK 370
Score = 35.9 bits (79), Expect = 0.60
Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 10/96 (10%)
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C+ + P P TW NG+ PV K + L+++NV SD +C
Sbjct: 2 CQVQGRPQPEVTWRINGI--PVEELAK------DQKYRIQRGALILSNVQPSDTMVTQCE 53
Query: 439 ARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
ARN G + V P ++ LT N T+ V
Sbjct: 54 ARNRHGLLLANAYIYVVQLPAKI--LTADNQTYMAV 87
>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 82.6 bits (195), Expect = 5e-15
Identities = 96/385 (24%), Positives = 161/385 (41%), Gaps = 34/385 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 360 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 416
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 417 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 474
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 475 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 529
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 530 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 580
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 581 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 640
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 641 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 699
Query: 541 YRPDDTKATTLTSSEVGELSTVSTE 565
P T +T E + V +
Sbjct: 700 --PSPVSETVVTPEAAPEKNPVDVK 722
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 243 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 295
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 296 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 355
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 356 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 413
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 414 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 470
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 471 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 522
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 523 GPRSTIEKKGSRVTFTCQASFDPSLQ 548
Score = 44.0 bits (99), Expect = 0.002
Identities = 73/322 (22%), Positives = 122/322 (37%), Gaps = 34/322 (10%)
Query: 156 DGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSG 214
+G V P+ + + V + + + A G P + + WT+DG+ +
Sbjct: 27 EGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKP-EVQFRWTRDGVHFKPKEELGVT 85
Query: 215 NDRIISEGSML---NMTKLTRHDAGIYTCEAVNSQGAAVAN-ISVSVH-YPAGIKSVSQN 269
+ GS N + + GIY C A N G A+++ I + P K +
Sbjct: 86 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 145
Query: 270 VVANPNEDAVLSCT--AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V E VL C PL + + K D + + NL ++ S+
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVL---TSD 202
Query: 328 NLGNFQCVVNNGIGSAT---KQDVMLIVKFKPEM-DTSPNFV---KSASNV----GQVGR 376
N ++ C + G+ T K+ + L VK M D P + S+S++ GQ
Sbjct: 203 NHSDYICHAHFP-GTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLV 261
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C + P P+ W + +P + T ++N + L + V D G Y
Sbjct: 262 LECIAEGFPTPTIKWLRPSGPMPADRVT------YQN----HNKTLQLLKVGEEDDGEYR 311
Query: 437 CGARNELGFSTTTVKLDVTSAP 458
C A N LG + + V +AP
Sbjct: 312 CLAENSLGSARHAYYVTVEAAP 333
>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
protein.
Length = 1253
Score = 82.6 bits (195), Expect = 5e-15
Identities = 96/385 (24%), Positives = 161/385 (41%), Gaps = 34/385 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 360 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 416
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 417 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 474
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 475 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 529
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 530 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 580
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 581 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 640
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 641 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 699
Query: 541 YRPDDTKATTLTSSEVGELSTVSTE 565
P T +T E + V +
Sbjct: 700 --PSPVSETVVTPEAAPEKNPVDVK 722
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 243 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 295
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 296 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 355
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 356 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 413
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 414 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 470
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 471 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 522
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 523 GPRSTIEKKGSRVTFTCQASFDPSLQ 548
Score = 44.0 bits (99), Expect = 0.002
Identities = 73/322 (22%), Positives = 122/322 (37%), Gaps = 34/322 (10%)
Query: 156 DGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSG 214
+G V P+ + + V + + + A G P + + WT+DG+ +
Sbjct: 27 EGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKP-EVQFRWTRDGVHFKPKEELGVT 85
Query: 215 NDRIISEGSML---NMTKLTRHDAGIYTCEAVNSQGAAVAN-ISVSVH-YPAGIKSVSQN 269
+ GS N + + GIY C A N G A+++ I + P K +
Sbjct: 86 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 145
Query: 270 VVANPNEDAVLSCT--AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V E VL C PL + + K D + + NL ++ S+
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVL---TSD 202
Query: 328 NLGNFQCVVNNGIGSAT---KQDVMLIVKFKPEM-DTSPNFV---KSASNV----GQVGR 376
N ++ C + G+ T K+ + L VK M D P + S+S++ GQ
Sbjct: 203 NHSDYICHAHFP-GTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLV 261
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C + P P+ W + +P + T ++N + L + V D G Y
Sbjct: 262 LECIAEGFPTPTIKWLRPSGPMPADRVT------YQN----HNKTLQLLKVGEEDDGEYR 311
Query: 437 CGARNELGFSTTTVKLDVTSAP 458
C A N LG + + V +AP
Sbjct: 312 CLAENSLGSARHAYYVTVEAAP 333
>BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 82.6 bits (195), Expect = 5e-15
Identities = 96/385 (24%), Positives = 161/385 (41%), Gaps = 34/385 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 360 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 416
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 417 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 474
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 475 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 529
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 530 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 580
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 581 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 640
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 641 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 699
Query: 541 YRPDDTKATTLTSSEVGELSTVSTE 565
P T +T E + V +
Sbjct: 700 --PSPVSETVVTPEAAPEKNPVDVK 722
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 243 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 295
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 296 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 355
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 356 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 413
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 414 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 470
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 471 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 522
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 523 GPRSTIEKKGSRVTFTCQASFDPSLQ 548
Score = 44.0 bits (99), Expect = 0.002
Identities = 73/322 (22%), Positives = 122/322 (37%), Gaps = 34/322 (10%)
Query: 156 DGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSG 214
+G V P+ + + V + + + A G P + + WT+DG+ +
Sbjct: 27 EGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKP-EVQFRWTRDGVHFKPKEELGVT 85
Query: 215 NDRIISEGSML---NMTKLTRHDAGIYTCEAVNSQGAAVAN-ISVSVH-YPAGIKSVSQN 269
+ GS N + + GIY C A N G A+++ I + P K +
Sbjct: 86 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 145
Query: 270 VVANPNEDAVLSCT--AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V E VL C PL + + K D + + NL ++ S+
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVL---TSD 202
Query: 328 NLGNFQCVVNNGIGSAT---KQDVMLIVKFKPEM-DTSPNFV---KSASNV----GQVGR 376
N ++ C + G+ T K+ + L VK M D P + S+S++ GQ
Sbjct: 203 NHSDYICHAHFP-GTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLV 261
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C + P P+ W + +P + T ++N + L + V D G Y
Sbjct: 262 LECIAEGFPTPTIKWLRPSGPMPADRVT------YQN----HNKTLQLLKVGEEDDGEYR 311
Query: 437 CGARNELGFSTTTVKLDVTSAP 458
C A N LG + + V +AP
Sbjct: 312 CLAENSLGSARHAYYVTVEAAP 333
>AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar to
hemicentin (LOC392395) protein.
Length = 746
Score = 82.6 bits (195), Expect = 5e-15
Identities = 71/274 (25%), Positives = 112/274 (40%), Gaps = 18/274 (6%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAV 279
S S + + ++ + G Y C AV+ G A + V P + NV +P E AV
Sbjct: 439 SGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAV 498
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNG 339
LSC +G ++ W R +++ P S + L I + G +QCV +N
Sbjct: 499 LSCRVLGE--APYNLTWVR-DWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNA 555
Query: 340 IGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
G T+ V L+V+ P++ + + V +V ++ C P P +WS+ L
Sbjct: 556 NG-VTRASVWLLVREAPQVSIHTSSQHFSQGV-EV-KVSCSASGYPTPHISWSRESQALQ 612
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP- 458
++ H+ L+I VA D G+Y C A NE+G TV L T P
Sbjct: 613 EDSRI----------HVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPS 662
Query: 459 -DQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYR 491
V ++ + V V + G WYR
Sbjct: 663 VSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR 696
Score = 72.9 bits (171), Expect = 4e-12
Identities = 68/275 (24%), Positives = 117/275 (42%), Gaps = 24/275 (8%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
E ++S R G P TW +D + S+ G +++ S L ++ + D G Y
Sbjct: 495 ETAVLSCRVLGEAP-YNLTWVRDWRVLPAST---GRVAQLADLS-LEISGIIPTDGGRYQ 549
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERK 299
C A N+ G A++ + V + + + + + +SC+A G P HI W R+
Sbjct: 550 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYP--TPHISWSRE 607
Query: 300 GYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD 359
+ S T LII+ E+ GN+ C N +G T Q+ + + P
Sbjct: 608 SQALQEDSRIHVDAQGT--LIIQGVAPEDAGNYSCQATNEVG--TDQETVTLYYTDPPSV 663
Query: 360 TSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYT 419
++ N V + VG+ L+C+ VP P W + G+++ + + +
Sbjct: 664 SAVNAVVLVA-VGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEG------------SSS 710
Query: 420 SVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
L I D G+Y C A NELG ++ ++L V
Sbjct: 711 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 745
Score = 50.4 bits (115), Expect = 3e-05
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 6/142 (4%)
Query: 23 APMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISI 82
AP ++ + + G K++C S G P ++W + + + ++ A I I
Sbjct: 570 APQVSIHTSSQHFSQGVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLI-I 627
Query: 83 LTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDS 142
++ Y C+ATN ETVTL P V A ++ G EA L+C+
Sbjct: 628 QGVAPEDAGNYSCQATNEVGTDQ--ETVTLYYTDPPSVSAVNAVV-LVAVGEEAVLVCE- 683
Query: 143 ASSNPPATLSWWRDGIPVQNAP 164
AS PP + W+R G+ + AP
Sbjct: 684 ASGVPPPRVIWYRGGLEMILAP 705
Score = 45.6 bits (103), Expect = 7e-04
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 8/144 (5%)
Query: 18 SDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVS 77
+DPP P + P T++ G L+C G P LTW ++ + + ++T +
Sbjct: 477 TDPP--PQLVP-APNVTVSPGETAVLSCRVLGEAPY-NLTWVRDWRVLPASTGRVAQLAD 532
Query: 78 AEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEAT 137
+ I + + +Y+C A+N A + +V L V AP+ V + G+E
Sbjct: 533 LSLEISGIIPTDGGRYQCVASN-ANGVTR-ASVWLLVREAPQ-VSIHTSSQHFSQGVEVK 589
Query: 138 LICDSASSNPPATLSWWRDGIPVQ 161
+ C SAS P +SW R+ +Q
Sbjct: 590 VSC-SASGYPTPHISWSRESQALQ 612
>AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1255
Score = 82.6 bits (195), Expect = 5e-15
Identities = 96/385 (24%), Positives = 161/385 (41%), Gaps = 34/385 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 358 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 414
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 415 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 472
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 473 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 527
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 528 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 578
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 579 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 638
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 639 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 697
Query: 541 YRPDDTKATTLTSSEVGELSTVSTE 565
P T +T E + V +
Sbjct: 698 --PSPVSETVVTPEAAPEKNPVDVK 720
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 241 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 293
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 294 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 353
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 354 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 411
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 412 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 468
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 469 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 520
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 521 GPRSTIEKKGSRVTFTCQASFDPSLQ 546
Score = 44.0 bits (99), Expect = 0.002
Identities = 73/322 (22%), Positives = 122/322 (37%), Gaps = 34/322 (10%)
Query: 156 DGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSG 214
+G V P+ + + V + + + A G P + + WT+DG+ +
Sbjct: 25 EGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKP-EVQFRWTRDGVHFKPKEELGVT 83
Query: 215 NDRIISEGSML---NMTKLTRHDAGIYTCEAVNSQGAAVAN-ISVSVH-YPAGIKSVSQN 269
+ GS N + + GIY C A N G A+++ I + P K +
Sbjct: 84 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 143
Query: 270 VVANPNEDAVLSCT--AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V E VL C PL + + K D + + NL ++ S+
Sbjct: 144 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVL---TSD 200
Query: 328 NLGNFQCVVNNGIGSAT---KQDVMLIVKFKPEM-DTSPNFV---KSASNV----GQVGR 376
N ++ C + G+ T K+ + L VK M D P + S+S++ GQ
Sbjct: 201 NHSDYICHAHFP-GTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLV 259
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C + P P+ W + +P + T ++N + L + V D G Y
Sbjct: 260 LECIAEGFPTPTIKWLRPSGPMPADRVT------YQN----HNKTLQLLKVGEEDDGEYR 309
Query: 437 CGARNELGFSTTTVKLDVTSAP 458
C A N LG + + V +AP
Sbjct: 310 CLAENSLGSARHAYYVTVEAAP 331
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 82.2 bits (194), Expect = 7e-15
Identities = 71/271 (26%), Positives = 114/271 (42%), Gaps = 26/271 (9%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNE 276
I + G++L + + D GIY CEA N +G + V +P ++ ++ V +
Sbjct: 288 ISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEV-DIGS 346
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
D C A G P+ I+W + GY + L Y + EN G +QC+
Sbjct: 347 DLYWPCVATGKPIPT--IRWLKNGY-------AYHKGELRLYDVT----FENAGMYQCIA 393
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ + I+ P + +P K + G + CK K+ P P F+WSK G
Sbjct: 394 ENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GT 452
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ VN+S E L INN+ +D G Y C A N G + +T L +T
Sbjct: 453 EWLVNSSRILIWE---------DGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 503
Query: 457 APDQVVSLTVTNVT-HSTVTLEWVPGFDGGL 486
+++ ++T T++ FD L
Sbjct: 504 PTRIILAPINADITVGENATMQCAASFDPAL 534
Score = 59.7 bits (138), Expect = 4e-08
Identities = 63/285 (22%), Positives = 109/285 (38%), Gaps = 16/285 (5%)
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG---IKSVSQNVVANPNEDAVLS 281
L + +T +AG+Y C A N+ GA AN + + A + + + ++A ++
Sbjct: 376 LRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C P W + + S ++ L I + G + C N G
Sbjct: 436 CKPKAAP--KPKFSWSKGTEWLVNSSRILIWED--GSLEINNITRNDGGIYTCFAENNRG 491
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP--SFTWSKNGVKLP 399
A ++I + +P + + VG+ + C PA +F WS NG +
Sbjct: 492 KANSTGTLVITD-PTRIILAP--INADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
N K + +N + LLI N G Y C A+ + S+ + L V P
Sbjct: 549 FN---KENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPG 605
Query: 460 QVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYK 503
L + ++ ++V L W G D S Y I+ + + D +K
Sbjct: 606 PPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWK 650
Score = 58.8 bits (136), Expect = 7e-08
Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 14/160 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P ++W+K T+ +S I +GS L + +TR+D GIYTC A N++G A +
Sbjct: 442 PKPKFSWSKG----TEWLVNSSRILIWEDGS-LEINNITRNDGGIYTCFAENNRGKANST 496
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID--PKSVTF 310
++ + P I N E+A + C A +P L W GY ID +++ +
Sbjct: 497 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 556
Query: 311 EPK---NLTSYLIIRKAKSENLGNFQC----VVNNGIGSA 343
+ + L+IR A+ ++ G + C +V+N SA
Sbjct: 557 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASA 596
Score = 46.0 bits (104), Expect = 6e-04
Identities = 51/215 (23%), Positives = 87/215 (40%), Gaps = 22/215 (10%)
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTC--------EA 242
P ++Y W + P+ + R +S+ L + + D G Y+C ++
Sbjct: 165 PDDLSYRWLLNEFPVF---ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKS 221
Query: 243 VNSQGAAVANIS--VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
V S+ + I + YPA I ++V A ++ L C A+GNP+ I+W +
Sbjct: 222 VFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPV--PDIRWRK-- 277
Query: 301 YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDT 360
++P T E + L I + E+ G ++C N I K + V+ PE
Sbjct: 278 -VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAEN-IRGKDKHQARIYVQAFPEWVE 335
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N + ++G C P P+ W KNG
Sbjct: 336 HIN--DTEVDIGSDLYWPCVATGKPIPTIRWLKNG 368
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 82.2 bits (194), Expect = 7e-15
Identities = 71/271 (26%), Positives = 114/271 (42%), Gaps = 26/271 (9%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNE 276
I + G++L + + D GIY CEA N +G + V +P ++ ++ V +
Sbjct: 277 ISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEV-DIGS 335
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
D C A G P+ I+W + GY + L Y + EN G +QC+
Sbjct: 336 DLYWPCVATGKPIPT--IRWLKNGY-------AYHKGELRLYDVT----FENAGMYQCIA 382
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ + I+ P + +P K + G + CK K+ P P F+WSK G
Sbjct: 383 ENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GT 441
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ VN+S E L INN+ +D G Y C A N G + +T L +T
Sbjct: 442 EWLVNSSRILIWE---------DGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 492
Query: 457 APDQVVSLTVTNVT-HSTVTLEWVPGFDGGL 486
+++ ++T T++ FD L
Sbjct: 493 PTRIILAPINADITVGENATMQCAASFDPAL 523
Score = 59.7 bits (138), Expect = 4e-08
Identities = 63/285 (22%), Positives = 109/285 (38%), Gaps = 16/285 (5%)
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG---IKSVSQNVVANPNEDAVLS 281
L + +T +AG+Y C A N+ GA AN + + A + + + ++A ++
Sbjct: 365 LRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 424
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C P W + + S ++ L I + G + C N G
Sbjct: 425 CKPKAAP--KPKFSWSKGTEWLVNSSRILIWED--GSLEINNITRNDGGIYTCFAENNRG 480
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP--SFTWSKNGVKLP 399
A ++I + +P + + VG+ + C PA +F WS NG +
Sbjct: 481 KANSTGTLVITD-PTRIILAP--INADITVGENATMQCAASFDPALDLTFVWSFNGYVID 537
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
N K + +N + LLI N G Y C A+ + S+ + L V P
Sbjct: 538 FN---KENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPG 594
Query: 460 QVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYK 503
L + ++ ++V L W G D S Y I+ + + D +K
Sbjct: 595 PPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWK 639
Score = 58.8 bits (136), Expect = 7e-08
Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 14/160 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P ++W+K T+ +S I +GS L + +TR+D GIYTC A N++G A +
Sbjct: 431 PKPKFSWSKG----TEWLVNSSRILIWEDGS-LEINNITRNDGGIYTCFAENNRGKANST 485
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID--PKSVTF 310
++ + P I N E+A + C A +P L W GY ID +++ +
Sbjct: 486 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 545
Query: 311 EPK---NLTSYLIIRKAKSENLGNFQC----VVNNGIGSA 343
+ + L+IR A+ ++ G + C +V+N SA
Sbjct: 546 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASA 585
Score = 46.0 bits (104), Expect = 6e-04
Identities = 51/215 (23%), Positives = 87/215 (40%), Gaps = 22/215 (10%)
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTC--------EA 242
P ++Y W + P+ + R +S+ L + + D G Y+C ++
Sbjct: 154 PDDLSYRWLLNEFPVF---ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKS 210
Query: 243 VNSQGAAVANIS--VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
V S+ + I + YPA I ++V A ++ L C A+GNP+ I+W +
Sbjct: 211 VFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPV--PDIRWRK-- 266
Query: 301 YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDT 360
++P T E + L I + E+ G ++C N I K + V+ PE
Sbjct: 267 -VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAEN-IRGKDKHQARIYVQAFPEWVE 324
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N + ++G C P P+ W KNG
Sbjct: 325 HIN--DTEVDIGSDLYWPCVATGKPIPTIRWLKNG 357
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 82.2 bits (194), Expect = 7e-15
Identities = 71/271 (26%), Positives = 114/271 (42%), Gaps = 26/271 (9%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNE 276
I + G++L + + D GIY CEA N +G + V +P ++ ++ V +
Sbjct: 288 ISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEV-DIGS 346
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
D C A G P+ I+W + GY + L Y + EN G +QC+
Sbjct: 347 DLYWPCVATGKPIPT--IRWLKNGY-------AYHKGELRLYDVT----FENAGMYQCIA 393
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ + I+ P + +P K + G + CK K+ P P F+WSK G
Sbjct: 394 ENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GT 452
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ VN+S E L INN+ +D G Y C A N G + +T L +T
Sbjct: 453 EWLVNSSRILIWE---------DGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 503
Query: 457 APDQVVSLTVTNVT-HSTVTLEWVPGFDGGL 486
+++ ++T T++ FD L
Sbjct: 504 PTRIILAPINADITVGENATMQCAASFDPAL 534
Score = 59.7 bits (138), Expect = 4e-08
Identities = 63/285 (22%), Positives = 109/285 (38%), Gaps = 16/285 (5%)
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG---IKSVSQNVVANPNEDAVLS 281
L + +T +AG+Y C A N+ GA AN + + A + + + ++A ++
Sbjct: 376 LRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C P W + + S ++ L I + G + C N G
Sbjct: 436 CKPKAAP--KPKFSWSKGTEWLVNSSRILIWED--GSLEINNITRNDGGIYTCFAENNRG 491
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP--SFTWSKNGVKLP 399
A ++I + +P + + VG+ + C PA +F WS NG +
Sbjct: 492 KANSTGTLVITD-PTRIILAP--INADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
N K + +N + LLI N G Y C A+ + S+ + L V P
Sbjct: 549 FN---KENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPG 605
Query: 460 QVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYK 503
L + ++ ++V L W G D S Y I+ + + D +K
Sbjct: 606 PPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWK 650
Score = 58.8 bits (136), Expect = 7e-08
Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 14/160 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P ++W+K T+ +S I +GS L + +TR+D GIYTC A N++G A +
Sbjct: 442 PKPKFSWSKG----TEWLVNSSRILIWEDGS-LEINNITRNDGGIYTCFAENNRGKANST 496
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID--PKSVTF 310
++ + P I N E+A + C A +P L W GY ID +++ +
Sbjct: 497 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 556
Query: 311 EPK---NLTSYLIIRKAKSENLGNFQC----VVNNGIGSA 343
+ + L+IR A+ ++ G + C +V+N SA
Sbjct: 557 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASA 596
Score = 46.0 bits (104), Expect = 6e-04
Identities = 51/215 (23%), Positives = 87/215 (40%), Gaps = 22/215 (10%)
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTC--------EA 242
P ++Y W + P+ + R +S+ L + + D G Y+C ++
Sbjct: 165 PDDLSYRWLLNEFPVF---ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKS 221
Query: 243 VNSQGAAVANIS--VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
V S+ + I + YPA I ++V A ++ L C A+GNP+ I+W +
Sbjct: 222 VFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPV--PDIRWRK-- 277
Query: 301 YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDT 360
++P T E + L I + E+ G ++C N I K + V+ PE
Sbjct: 278 -VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAEN-IRGKDKHQARIYVQAFPEWVE 335
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N + ++G C P P+ W KNG
Sbjct: 336 HIN--DTEVDIGSDLYWPCVATGKPIPTIRWLKNG 368
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 82.2 bits (194), Expect = 7e-15
Identities = 71/271 (26%), Positives = 114/271 (42%), Gaps = 26/271 (9%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNE 276
I + G++L + + D GIY CEA N +G + V +P ++ ++ V +
Sbjct: 288 ISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEV-DIGS 346
Query: 277 DAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV 336
D C A G P+ I+W + GY + L Y + EN G +QC+
Sbjct: 347 DLYWPCVATGKPIPT--IRWLKNGY-------AYHKGELRLYDVT----FENAGMYQCIA 393
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ + I+ P + +P K + G + CK K+ P P F+WSK G
Sbjct: 394 ENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GT 452
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ VN+S E L INN+ +D G Y C A N G + +T L +T
Sbjct: 453 EWLVNSSRILIWE---------DGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 503
Query: 457 APDQVVSLTVTNVT-HSTVTLEWVPGFDGGL 486
+++ ++T T++ FD L
Sbjct: 504 PTRIILAPINADITVGENATMQCAASFDPAL 534
Score = 60.5 bits (140), Expect = 2e-08
Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 11/180 (6%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P ++W+K T+ +S I +GS L + +TR+D GIYTC A N++G A +
Sbjct: 442 PKPKFSWSKG----TEWLVNSSRILIWEDGS-LEINNITRNDGGIYTCFAENNRGKANST 496
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID--PKSVTF 310
++ + P I N E+A + C A +P L W GY ID +++ +
Sbjct: 497 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 556
Query: 311 EPK---NLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKS 367
+ + L+IR A+ ++ G + C + +++ L+V+ K N V S
Sbjct: 557 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSS-ASADLVVRGKNRKGGEKNMVDS 615
Score = 46.0 bits (104), Expect = 6e-04
Identities = 51/215 (23%), Positives = 87/215 (40%), Gaps = 22/215 (10%)
Query: 192 PPSITYTWTKDGLPITQSSYSSGNDRIISE-GSMLNMTKLTRHDAGIYTC--------EA 242
P ++Y W + P+ + R +S+ L + + D G Y+C ++
Sbjct: 165 PDDLSYRWLLNEFPVF---ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKS 221
Query: 243 VNSQGAAVANIS--VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG 300
V S+ + I + YPA I ++V A ++ L C A+GNP+ I+W +
Sbjct: 222 VFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPV--PDIRWRK-- 277
Query: 301 YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDT 360
++P T E + L I + E+ G ++C N I K + V+ PE
Sbjct: 278 -VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAEN-IRGKDKHQARIYVQAFPEWVE 335
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
N + ++G C P P+ W KNG
Sbjct: 336 HIN--DTEVDIGSDLYWPCVATGKPIPTIRWLKNG 368
Score = 43.2 bits (97), Expect = 0.004
Identities = 51/235 (21%), Positives = 88/235 (37%), Gaps = 15/235 (6%)
Query: 225 LNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG---IKSVSQNVVANPNEDAVLS 281
L + +T +AG+Y C A N+ GA AN + + A + + + ++A ++
Sbjct: 376 LRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
Query: 282 CTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
C P W + + S ++ L I + G + C N G
Sbjct: 436 CKPKAAP--KPKFSWSKGTEWLVNSSRILIWED--GSLEINNITRNDGGIYTCFAENNRG 491
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAP--SFTWSKNGVKLP 399
A ++I + +P + + VG+ + C PA +F WS NG +
Sbjct: 492 KANSTGTLVITD-PTRIILAP--INADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
N K + +N + LLI N G Y C A+ + S+ + L V
Sbjct: 549 FN---KENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV 600
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 82.2 bits (194), Expect = 7e-15
Identities = 107/425 (25%), Positives = 170/425 (40%), Gaps = 42/425 (9%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + T N V E + RA+GNP P I+ W +G+PI + + +
Sbjct: 343 VRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNPKPRIS--WLTNGVPI-EIAPDDPSR 398
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV--HYPAGIKSVSQNVVANP 274
+I +G + + + + +Y C A N G +AN V+V P + +
Sbjct: 399 KI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIA 456
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N A+L C G+PL I+W KG K + L I A+ ++ G + C
Sbjct: 457 NRPALLDCAFFGSPLPT--IEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 513
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WS 392
V N +G A K +V L +K + P + + G + CK K S T W
Sbjct: 514 VARNKLGMA-KNEVHLEIKDATWIVKQPEY--AVVQRGSMVSFECKVKHDHTLSLTVLWL 570
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ +LP S + F DH L++ +V+ D G+Y C A L + + L
Sbjct: 571 KDNRELP---SDERFTV--DKDH------LVVADVSDDDSGTYTCVANTTLDSVSASAVL 619
Query: 453 DVTS----------APDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDS 501
V + P+ L +T+ +V L W PG D + + I Y
Sbjct: 620 SVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKP 679
Query: 502 YKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELS 560
+ T T L +Y F VMA+N IG+S P + LT + + +
Sbjct: 680 GLWHHQTEVSGTQTTAQLNLSPYVNYSFRVMAVNSIGKS--LPSEASEQYLTKASEPDKN 737
Query: 561 TVSTE 565
+ E
Sbjct: 738 PTAVE 742
Score = 71.7 bits (168), Expect = 1e-11
Identities = 74/287 (25%), Positives = 114/287 (39%), Gaps = 22/287 (7%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDG-LPITQSSYSSGNDRIISEGSMLNMTKLT 231
N + L + A+G P I Y +DG LP ++ Y + L + ++
Sbjct: 267 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE-------KTLQIIHVS 319
Query: 232 RHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA 291
D+G Y C A N+ GA ISV V + QN+V +P ED L C A GNP
Sbjct: 320 EADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNP--K 377
Query: 292 EHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI 351
I W G I+ K +I + + +QC +N G + +
Sbjct: 378 PRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV 437
Query: 352 VKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
+ P + T N + + L C P P+ W K G K + H
Sbjct: 438 LAEPPRILTPANTLYQVI-ANRPALLDCAFFGSPLPTIEWFK-GAK---------GSALH 486
Query: 412 KNDHITYTSVLLINNVATSD-YGSYECGARNELGFSTTTVKLDVTSA 457
++ ++ + + L VA D G+Y C ARN+LG + V L++ A
Sbjct: 487 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDA 533
Score = 67.3 bits (157), Expect = 2e-10
Identities = 69/266 (25%), Positives = 113/266 (42%), Gaps = 21/266 (7%)
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
VLS I L I W ++ + PK+ T KN L I + GN+QC+ N
Sbjct: 275 VLSLECIAEGLPTPIIYWAKEDGML-PKNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKN 332
Query: 339 GIGSATKQDVMLIVKFKPEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
+G A + + VK P T+P N V S G+ G L+C+ P P +W NGV
Sbjct: 333 ALG-AIHHTISVRVKAAPYWITAPQNLVLSP---GEDGTLICRANGNPKPRISWLTNGVP 388
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
+ + K D T ++ +NV Y+C A NE G+ ++V +
Sbjct: 389 IEIAPDDPS----RKIDGDT----IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 440
Query: 458 PDQVV--SLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHAT-N 514
P +++ + T+ V + L F L + I + K S +ED+ H
Sbjct: 441 PPRILTPANTLYQVIANRPALLDCAFFGSPLPT---IEWFKGAKGSALHEDIYVLHENGT 497
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
+ +K++ ++ +A NK+G +K
Sbjct: 498 LEIPVAQKDSTGTYTCVARNKLGMAK 523
Score = 62.9 bits (146), Expect = 5e-09
Identities = 78/302 (25%), Positives = 125/302 (41%), Gaps = 44/302 (14%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGL-------PITQSSYSSGN--DRIISEGSMLNMTKL 230
E ++I A G PP +++WT++G P+ +G I+SEG K
Sbjct: 69 ENIVIQCEAKGKPPP-SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG------KA 121
Query: 231 TRHDAGIYTCEAVNSQGAAVANISV--SVHYPAGIKSVSQNVVANPNEDAVLSCTA-IGN 287
++ G+Y C A N +GAAV+N V P K + + + VL C IG
Sbjct: 122 ETYE-GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 180
Query: 288 PLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLG-NFQCVV--NNGIGSAT 344
P I W ++ P+S + L L E+ ++ C N+
Sbjct: 181 P--PPIIFWMDNSFQRLPQSERVS-QGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQ 237
Query: 345 KQDVML-IVKFKPEMDTSPNFVKSASNV-------GQVGRLMCKCKSVPAPSFTWSKNGV 396
KQ + + ++ K + P F+ N G V L C + +P P W+K
Sbjct: 238 KQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDG 297
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
LP N + +KN + L I +V+ +D G+Y+C A+N LG T+ + V +
Sbjct: 298 MLPKNRTV------YKN----FEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 347
Query: 457 AP 458
AP
Sbjct: 348 AP 349
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Query: 15 NSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDK 74
+S PP+ G G V L CI+ G P + W K D + +T K
Sbjct: 250 SSRERPPTFLTPEGNASNKEELRGNVLSLECIAEG-LPTPIIYWAKEDGMLPKN-RTVYK 307
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
+ I+ + Y+C A N+ I T+++ V AP + + VL PG
Sbjct: 308 NFEKTLQIIHVSEADSGNYQCIAKNALGAI--HHTISVRVKAAPYWITA-PQNLVLSPGE 364
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAP 164
+ TLIC A+ NP +SW +G+P++ AP
Sbjct: 365 DGTLIC-RANGNPKPRISWLTNGVPIEIAP 393
Score = 39.5 bits (88), Expect = 0.048
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 257 VHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG--YKIDPKS-VTFEPK 313
V P + ++ + +P E+ V+ C A G P W R G + ID VT +P
Sbjct: 50 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKP--PPSFSWTRNGTHFDIDKDPLVTMKPG 107
Query: 314 NLTSYL-IIRKAKSENL-GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV 371
T + I+ + K+E G +QC N G+A ++++ P + T
Sbjct: 108 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP-LWTKEKLEPITLQS 166
Query: 372 GQVGRLMCKCK-SVPAPSFTWSKNGV-KLP 399
GQ L C+ +P P W N +LP
Sbjct: 167 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLP 196
Score = 38.7 bits (86), Expect = 0.084
Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 21/155 (13%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV----L 508
V SAP SL + N T ++TLEW P G+ + Y ++Y+ + + +++ + +
Sbjct: 939 VPSAPS---SLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPI-NSTHELGPLVDLKI 994
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVE 568
P + T +T+ L +T Y F A G ++ TT+ + ++T+
Sbjct: 995 PANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA-VTTVDEAMASRQVDIATQG-- 1051
Query: 569 TPDISKPVIVYVSLTGAVLVLINVALIACFVWKRR 603
++ L AV +LI + LI CF+ + +
Sbjct: 1052 ---------WFIGLMCAVALLILILLIVCFIRRNK 1077
Score = 32.3 bits (70), Expect = 7.3
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTD-NQAQY 93
L+ G L C GNP ++W N I + + + I +NV + + A Y
Sbjct: 360 LSPGEDGTLIC-RANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVY 418
Query: 94 RCEATN 99
+C A+N
Sbjct: 419 QCNASN 424
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 81.8 bits (193), Expect = 9e-15
Identities = 97/385 (25%), Positives = 154/385 (40%), Gaps = 44/385 (11%)
Query: 174 TVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR--IISEGSMLNMTKLT 231
TVG E + G P + TW K+ +PI + N+R ++ +G +L +T L
Sbjct: 148 TVGEEGGVARFQCQIHGLPKPLI-TWEKNRVPI-----DTDNERYTLLPKG-VLQITGLR 200
Query: 232 RHDAGIYTCEAVN------SQGA--AVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
D GI+ C A N S GA V+ + I +N+ ++ AVL C
Sbjct: 201 AEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECV 260
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL--TSYLIIRKAKSENLGNFQCVVNNGIG 341
A GNP + W R +D + + E + T LII ++ G + C N G
Sbjct: 261 ATGNP--RPIVSWSR----LDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRP-G 313
Query: 342 SATKQDVM--LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
+ ++ L+V+ E P + + G C+ + P P TW KNG L
Sbjct: 314 TRVRRTAQGRLVVQAPAEFVQHPQSISRPA--GTTAMFTCQAQGEPPPHVTWLKNGQVLG 371
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA-- 457
+ KN++ S L I+ + D Y+C A N G S + +L V A
Sbjct: 372 PGGHVRL-----KNNN----STLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEG 422
Query: 458 -PDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFD-DSYKYEDVLPKHATN 514
P ++ +V+ + V + W + Y + RK D +Y++ + K
Sbjct: 423 LPGPPRNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAVSKSTFQ 482
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQS 539
V LE +T Y F + A G S
Sbjct: 483 HLVSDLEPSTAYSFYIKAYTPRGAS 507
Score = 52.0 bits (119), Expect = 8e-06
Identities = 67/278 (24%), Positives = 107/278 (38%), Gaps = 33/278 (11%)
Query: 175 VGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGS-MLNMTKL--- 230
V + +P+++ R +G PP + TW K+G+ + +S++S+ +++ GS M+ +L
Sbjct: 52 VAVPGQPIVLDCRVEGTPP-VRITWRKNGVELPESTHST----LLANGSLMIRHFRLEPG 106
Query: 231 -TRHDAGIYTCEAVNSQGAAVA-NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP 288
+ D G Y C A N G V+ + + Q V A C G P
Sbjct: 107 GSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLP 166
Query: 289 LLAEHIKWERKGYKIDP--KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ 346
I WE+ ID + T PK + L I ++E+ G F CV +N
Sbjct: 167 --KPLITWEKNRVPIDTDNERYTLLPKGV---LQITGLRAEDGGIFHCVASNIASIRISH 221
Query: 347 DVMLIVKFKPE-MDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
L V P + N V Q L C P P +WS+ + P+
Sbjct: 222 GARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGR-PIG 280
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGA 439
+ + T L+I++V G Y C A
Sbjct: 281 V---------EGIQVLGTGNLIISDVTVQHSGVYVCAA 309
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/166 (27%), Positives = 66/166 (39%), Gaps = 11/166 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
GQ L C+ + P TW KNGV+LP +T + A N + L + SD
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLA----NGSLMIRHFRLEPGGSPSD 111
Query: 432 YGSYECGARNELGFSTT-TVKLDVTSAPDQVVSLTVTNVTHSTVTLE--WVPGFDGGLQS 488
G YEC A+N G + ++ + D V T V + G L +
Sbjct: 112 EGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLIT 171
Query: 489 WYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAIN 534
W + R + D+ +Y +LPK T GL IF +A N
Sbjct: 172 WEKNRV-PIDTDNERY-TLLPKGVLQIT--GLRAEDGGIFHCVASN 213
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 81.8 bits (193), Expect = 9e-15
Identities = 97/385 (25%), Positives = 154/385 (40%), Gaps = 44/385 (11%)
Query: 174 TVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR--IISEGSMLNMTKLT 231
TVG E + G P + TW K+ +PI + N+R ++ +G +L +T L
Sbjct: 148 TVGEEGGVARFQCQIHGLPKPLI-TWEKNRVPI-----DTDNERYTLLPKG-VLQITGLR 200
Query: 232 RHDAGIYTCEAVN------SQGA--AVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
D GI+ C A N S GA V+ + I +N+ ++ AVL C
Sbjct: 201 AEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECV 260
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL--TSYLIIRKAKSENLGNFQCVVNNGIG 341
A GNP + W R +D + + E + T LII ++ G + C N G
Sbjct: 261 ATGNP--RPIVSWSR----LDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRP-G 313
Query: 342 SATKQDVM--LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
+ ++ L+V+ E P + + G C+ + P P TW KNG L
Sbjct: 314 TRVRRTAQGRLVVQAPAEFVQHPQSISRPA--GTTAMFTCQAQGEPPPHVTWLKNGQVLG 371
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA-- 457
+ KN++ S L I+ + D Y+C A N G S + +L V A
Sbjct: 372 PGGHVRL-----KNNN----STLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEG 422
Query: 458 -PDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFD-DSYKYEDVLPKHATN 514
P ++ +V+ + V + W + Y + RK D +Y++ + K
Sbjct: 423 LPGPPRNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAVSKSTFQ 482
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQS 539
V LE +T Y F + A G S
Sbjct: 483 HLVSDLEPSTAYSFYIKAYTPRGAS 507
Score = 52.0 bits (119), Expect = 8e-06
Identities = 67/278 (24%), Positives = 107/278 (38%), Gaps = 33/278 (11%)
Query: 175 VGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGS-MLNMTKL--- 230
V + +P+++ R +G PP + TW K+G+ + +S++S+ +++ GS M+ +L
Sbjct: 52 VAVPGQPIVLDCRVEGTPP-VRITWRKNGVELPESTHST----LLANGSLMIRHFRLEPG 106
Query: 231 -TRHDAGIYTCEAVNSQGAAVA-NISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP 288
+ D G Y C A N G V+ + + Q V A C G P
Sbjct: 107 GSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLP 166
Query: 289 LLAEHIKWERKGYKIDP--KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQ 346
I WE+ ID + T PK + L I ++E+ G F CV +N
Sbjct: 167 --KPLITWEKNRVPIDTDNERYTLLPKGV---LQITGLRAEDGGIFHCVASNIASIRISH 221
Query: 347 DVMLIVKFKPE-MDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
L V P + N V Q L C P P +WS+ + P+
Sbjct: 222 GARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGR-PIG 280
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGA 439
+ + T L+I++V G Y C A
Sbjct: 281 V---------EGIQVLGTGNLIISDVTVQHSGVYVCAA 309
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/166 (27%), Positives = 66/166 (39%), Gaps = 11/166 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
GQ L C+ + P TW KNGV+LP +T + A N + L + SD
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLA----NGSLMIRHFRLEPGGSPSD 111
Query: 432 YGSYECGARNELGFSTT-TVKLDVTSAPDQVVSLTVTNVTHSTVTLE--WVPGFDGGLQS 488
G YEC A+N G + ++ + D V T V + G L +
Sbjct: 112 EGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLIT 171
Query: 489 WYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAIN 534
W + R + D+ +Y +LPK T GL IF +A N
Sbjct: 172 WEKNRV-PIDTDNERY-TLLPKGVLQIT--GLRAEDGGIFHCVASN 213
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhesion
molecule 2 protein.
Length = 2113
Score = 81.8 bits (193), Expect = 9e-15
Identities = 86/372 (23%), Positives = 147/372 (39%), Gaps = 16/372 (4%)
Query: 186 VRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNS 245
V + G+ P I TW KDG I S + + ++ L +H+ G YTC A N+
Sbjct: 678 VVSSGDMP-IRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSL-KHN-GNYTCIASNA 734
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP---LLAEHIKWERKGYK 302
+ V P N + VL+C+ G P ++ +H K +
Sbjct: 735 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 794
Query: 303 IDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
P +T + L S L+IR E++G + C +NG+G+ + + L VK + +
Sbjct: 795 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSH 854
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
PN + + G L C + W K + + +Y A K++ S
Sbjct: 855 PN--TTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRY-AIATKDNGDEVVST 911
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L + D + C A N G ++L V PD L + V ++ L W
Sbjct: 912 LKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDP-PELEIREVKARSMNLRWTQR 970
Query: 482 FDG-GLQSWYRIRYRKVFDDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
FDG + + + I Y+ DS+ ++ + + L + Y + + NKIG
Sbjct: 971 FDGNSIITGFDIEYKNK-SDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIG 1029
Query: 538 QSKYRPDDTKAT 549
+S+ + T +T
Sbjct: 1030 RSEPSKELTIST 1041
Score = 81.0 bits (191), Expect = 2e-14
Identities = 76/306 (24%), Positives = 120/306 (39%), Gaps = 16/306 (5%)
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P P+I W KDG P+ S R + L ++ L D+G Y CE N+
Sbjct: 309 ASGYPIPAIR--WLKDGRPLPADS------RWTKRITGLTISDLRTEDSGTYICEVTNTF 360
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A A + V P + + + +LSC G+P I+W R + P
Sbjct: 361 GSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFT--IRWYRNTELVLPD 418
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
L+I A+ + G +QC + T QD +I +F +
Sbjct: 419 EAISIRGLSNETLLITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGTPRIVSSFSE 476
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
N G+ LMC K P P+ TW+ + + V + ++ +D T S + +
Sbjct: 477 KVVNPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHRTNQYTMSDGTT-ISHMNVTG 534
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT-HSTVTLEWVPGFDGG 485
D G Y C ARN +G + +++V P +T V T+ V G+
Sbjct: 535 PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYY 594
Query: 486 LQSWYR 491
WY+
Sbjct: 595 SIKWYK 600
Score = 72.5 bits (170), Expect = 6e-12
Identities = 52/167 (31%), Positives = 77/167 (46%), Gaps = 11/167 (6%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
RL C PAP+ W+K+ + S H N LL+ V D G Y
Sbjct: 1368 RLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN------GTLLLRAVKAEDSGYY 1421
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRY 494
C A N GF T V L V PDQ LTV+ + S++TL W+PG +GG + ++Y
Sbjct: 1422 TCTATNTGGFDTIIVNLLVQVPPDQ-PRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1480
Query: 495 RKVFDDSYKYEDV-LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
D+S +++DV + +F + L+ T Y + A N +G +
Sbjct: 1481 S--VDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1525
Score = 50.0 bits (114), Expect = 3e-05
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 5/124 (4%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQYRCE 96
G+ L+C TG +P T+ W++N + + + + +S E ++T+ + Y+C
Sbjct: 389 GSTVILSCALTG-SPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 447
Query: 97 ATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
AT A F + L P V +E V+ PG + +L+C +A PP T++W D
Sbjct: 448 ATRKAQTAQDFAIIALE-DGTPRIVSSFSE-KVVNPGEQFSLMC-AAKGAPPPTVTWALD 504
Query: 157 GIPV 160
P+
Sbjct: 505 DEPI 508
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 16 SPSDPP-SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDK 74
S +DP S P I + AG +L C ++G P+ + W K+ + + + ++ T +
Sbjct: 277 SVTDPAESIPTILDGFHSQEVWAGHTVELPCTASG-YPIPAIRWLKDGRPLPADSRWTKR 335
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
IS L T++ Y CE TN+ + + + V P LK GI
Sbjct: 336 ITGLTISDLR--TEDSGTYICEVTNT-----FGSAEATGILMVIDPLHVTLTPKKLKTGI 388
Query: 135 EATLICDSA-SSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIIS 185
+T+I A + +P T+ W+R N + + + G+ NE L+I+
Sbjct: 389 GSTVILSCALTGSPEFTIRWYR------NTELVLPDEAISIRGLSNETLLIT 434
Score = 37.5 bits (83), Expect = 0.19
Identities = 36/160 (22%), Positives = 59/160 (36%), Gaps = 16/160 (10%)
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ WE+ I P+ F + Y I K + L ++C+ + T+Q +
Sbjct: 219 VSWEKDTVSIIPEHRFFITYHGGLY-ISDVQKEDALSTYRCITKHKYSGETRQSNGARLS 277
Query: 354 FKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
++ P + + G L C P P+ W K+G LP A+
Sbjct: 278 VTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLP--------AD 329
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
IT L I+++ T D G+Y C N G + T
Sbjct: 330 SRWTKRIT---GLTISDLRTEDSGTYICEVTNTFGSAEAT 366
Score = 33.5 bits (73), Expect = 3.2
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 242 AVNSQGAAVANISVSVH----YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
AV S G ++ V++ PA I S V +D L C ++G+P A +KW
Sbjct: 1327 AVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP--APAVKWT 1384
Query: 298 RKGYKIDPKSVTFEPKNL---TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
K + V+ + L L++R K+E+ G + C N G V L+V+
Sbjct: 1385 -KDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATN-TGGFDTIIVNLLVQV 1442
Query: 355 KPEMDTSPNFVKSASNV 371
P+ SAS++
Sbjct: 1443 PPDQPRLTVSKTSASSI 1459
Score = 33.5 bits (73), Expect = 3.2
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P+ WTKD G+ I + G++L + + D+G YTC A N+ G
Sbjct: 1377 PAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLL-LRAVKAEDSGYYTCTATNTGGFDTII 1435
Query: 253 ISVSVHYP 260
+++ V P
Sbjct: 1436 VNLLVQVP 1443
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule DSCAML1 protein.
Length = 2053
Score = 81.8 bits (193), Expect = 9e-15
Identities = 86/372 (23%), Positives = 147/372 (39%), Gaps = 16/372 (4%)
Query: 186 VRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNS 245
V + G+ P I TW KDG I S + + ++ L +H+ G YTC A N+
Sbjct: 618 VVSSGDMP-IRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSL-KHN-GNYTCIASNA 674
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP---LLAEHIKWERKGYK 302
+ V P N + VL+C+ G P ++ +H K +
Sbjct: 675 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734
Query: 303 IDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
P +T + L S L+IR E++G + C +NG+G+ + + L VK + +
Sbjct: 735 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSH 794
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
PN + + G L C + W K + + +Y A K++ S
Sbjct: 795 PN--TTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRY-AIATKDNGDEVVST 851
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L + D + C A N G ++L V PD L + V ++ L W
Sbjct: 852 LKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDP-PELEIREVKARSMNLRWTQR 910
Query: 482 FDG-GLQSWYRIRYRKVFDDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
FDG + + + I Y+ DS+ ++ + + L + Y + + NKIG
Sbjct: 911 FDGNSIITGFDIEYKNK-SDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIG 969
Query: 538 QSKYRPDDTKAT 549
+S+ + T +T
Sbjct: 970 RSEPSKELTIST 981
Score = 81.0 bits (191), Expect = 2e-14
Identities = 76/306 (24%), Positives = 120/306 (39%), Gaps = 16/306 (5%)
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P P+I W KDG P+ S R + L ++ L D+G Y CE N+
Sbjct: 249 ASGYPIPAIR--WLKDGRPLPADS------RWTKRITGLTISDLRTEDSGTYICEVTNTF 300
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A A + V P + + + +LSC G+P I+W R + P
Sbjct: 301 GSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFT--IRWYRNTELVLPD 358
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
L+I A+ + G +QC + T QD +I +F +
Sbjct: 359 EAISIRGLSNETLLITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGTPRIVSSFSE 416
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
N G+ LMC K P P+ TW+ + + V + ++ +D T S + +
Sbjct: 417 KVVNPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHRTNQYTMSDGTT-ISHMNVTG 474
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT-HSTVTLEWVPGFDGG 485
D G Y C ARN +G + +++V P +T V T+ V G+
Sbjct: 475 PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYY 534
Query: 486 LQSWYR 491
WY+
Sbjct: 535 SIKWYK 540
Score = 72.5 bits (170), Expect = 6e-12
Identities = 52/167 (31%), Positives = 77/167 (46%), Gaps = 11/167 (6%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
RL C PAP+ W+K+ + S H N LL+ V D G Y
Sbjct: 1308 RLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN------GTLLLRAVKAEDSGYY 1361
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRY 494
C A N GF T V L V PDQ LTV+ + S++TL W+PG +GG + ++Y
Sbjct: 1362 TCTATNTGGFDTIIVNLLVQVPPDQ-PRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1420
Query: 495 RKVFDDSYKYEDV-LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
D+S +++DV + +F + L+ T Y + A N +G +
Sbjct: 1421 S--VDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1465
Score = 50.0 bits (114), Expect = 3e-05
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 5/124 (4%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQYRCE 96
G+ L+C TG +P T+ W++N + + + + +S E ++T+ + Y+C
Sbjct: 329 GSTVILSCALTG-SPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 387
Query: 97 ATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
AT A F + L P V +E V+ PG + +L+C +A PP T++W D
Sbjct: 388 ATRKAQTAQDFAIIALE-DGTPRIVSSFSE-KVVNPGEQFSLMC-AAKGAPPPTVTWALD 444
Query: 157 GIPV 160
P+
Sbjct: 445 DEPI 448
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 16 SPSDPP-SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDK 74
S +DP S P I + AG +L C ++G P+ + W K+ + + + ++ T +
Sbjct: 217 SVTDPAESIPTILDGFHSQEVWAGHTVELPCTASG-YPIPAIRWLKDGRPLPADSRWTKR 275
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
IS L T++ Y CE TN+ + + + V P LK GI
Sbjct: 276 ITGLTISDLR--TEDSGTYICEVTNT-----FGSAEATGILMVIDPLHVTLTPKKLKTGI 328
Query: 135 EATLICDSA-SSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIIS 185
+T+I A + +P T+ W+R N + + + G+ NE L+I+
Sbjct: 329 GSTVILSCALTGSPEFTIRWYR------NTELVLPDEAISIRGLSNETLLIT 374
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/160 (22%), Positives = 60/160 (37%), Gaps = 16/160 (10%)
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ WE+ I P++ F + Y I K + L ++C+ + T+Q +
Sbjct: 159 VSWEKDTVSIIPENRFFITYHGGLY-ISDVQKEDALSTYRCITKHKYSGETRQSNGARLS 217
Query: 354 FKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
++ P + + G L C P P+ W K+G LP A+
Sbjct: 218 VTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLP--------AD 269
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
IT L I+++ T D G+Y C N G + T
Sbjct: 270 SRWTKRIT---GLTISDLRTEDSGTYICEVTNTFGSAEAT 306
Score = 33.5 bits (73), Expect = 3.2
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 242 AVNSQGAAVANISVSVH----YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
AV S G ++ V++ PA I S V +D L C ++G+P A +KW
Sbjct: 1267 AVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP--APAVKWT 1324
Query: 298 RKGYKIDPKSVTFEPKNL---TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
K + V+ + L L++R K+E+ G + C N G V L+V+
Sbjct: 1325 -KDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATN-TGGFDTIIVNLLVQV 1382
Query: 355 KPEMDTSPNFVKSASNV 371
P+ SAS++
Sbjct: 1383 PPDQPRLTVSKTSASSI 1399
Score = 33.5 bits (73), Expect = 3.2
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P+ WTKD G+ I + G++L + + D+G YTC A N+ G
Sbjct: 1317 PAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLL-LRAVKAEDSGYYTCTATNTGGFDTII 1375
Query: 253 ISVSVHYP 260
+++ V P
Sbjct: 1376 VNLLVQVP 1383
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1a protein.
Length = 2053
Score = 81.8 bits (193), Expect = 9e-15
Identities = 76/306 (24%), Positives = 120/306 (39%), Gaps = 16/306 (5%)
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P P+I W KDG P+ S R + L ++ L D+G Y CE N+
Sbjct: 249 ASGYPIPAIR--WLKDGRPLPADS------RWTKRITGLTISDLRTEDSGTYICEVTNTF 300
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A A + V P + + + +LSC G+P I+W R + P
Sbjct: 301 GSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFT--IRWYRNTELVLPD 358
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
L+I A+ + G +QC + T QD +I +F +
Sbjct: 359 EAISIRGLSNETLLITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGTPRIVSSFSE 416
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
N G+ LMC K P P+ TW+ + + V + ++ +D T S + +
Sbjct: 417 KVVNPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHRTNQYTMSDGTT-ISYMNVTG 474
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT-HSTVTLEWVPGFDGG 485
D G Y C ARN +G + +++V P +T V T+ V G+
Sbjct: 475 PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYY 534
Query: 486 LQSWYR 491
WY+
Sbjct: 535 SIKWYK 540
Score = 77.8 bits (183), Expect = 1e-13
Identities = 85/372 (22%), Positives = 146/372 (39%), Gaps = 16/372 (4%)
Query: 186 VRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNS 245
V + G+ P I TW KDG I S + + ++ L +H+ G TC A N+
Sbjct: 618 VVSSGDMP-IRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSL-KHN-GNDTCIASNA 674
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP---LLAEHIKWERKGYK 302
+ V P N + VL+C+ G P ++ +H K +
Sbjct: 675 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734
Query: 303 IDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
P +T + L S L+IR E++G + C +NG+G+ + + L VK + +
Sbjct: 735 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSH 794
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
PN + + G L C + W K + + +Y A K++ S
Sbjct: 795 PN--TTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRY-AIATKDNGDEVVST 851
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L + D + C A N G ++L V PD L + V ++ L W
Sbjct: 852 LKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDP-PELEIREVKARSMNLRWTQR 910
Query: 482 FDG-GLQSWYRIRYRKVFDDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
FDG + + + I Y+ DS+ ++ + + L + Y + + NKIG
Sbjct: 911 FDGNSIITGFDIEYKNK-SDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIG 969
Query: 538 QSKYRPDDTKAT 549
+S+ + T +T
Sbjct: 970 RSEPSKELTIST 981
Score = 72.5 bits (170), Expect = 6e-12
Identities = 52/167 (31%), Positives = 77/167 (46%), Gaps = 11/167 (6%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
RL C PAP+ W+K+ + S H N LL+ V D G Y
Sbjct: 1308 RLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN------GTLLLRAVKAEDSGYY 1361
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRY 494
C A N GF T V L V PDQ LTV+ + S++TL W+PG +GG + ++Y
Sbjct: 1362 TCTATNTGGFDTIIVNLLVQVPPDQ-PRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1420
Query: 495 RKVFDDSYKYEDV-LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
D+S +++DV + +F + L+ T Y + A N +G +
Sbjct: 1421 S--VDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1465
Score = 50.0 bits (114), Expect = 3e-05
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 5/124 (4%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQYRCE 96
G+ L+C TG +P T+ W++N + + + + +S E ++T+ + Y+C
Sbjct: 329 GSTVILSCALTG-SPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 387
Query: 97 ATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
AT A F + L P V +E V+ PG + +L+C +A PP T++W D
Sbjct: 388 ATRKAQTAQDFAIIALE-DGTPRIVSSFSE-KVVNPGEQFSLMC-AAKGAPPPTVTWALD 444
Query: 157 GIPV 160
P+
Sbjct: 445 DEPI 448
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 16 SPSDPP-SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDK 74
S +DP S P I + AG +L C ++G P+ + W K+ + + + ++ T +
Sbjct: 217 SVTDPAESIPTILDGFHSQEVWAGHTVELPCTASG-YPIPAIRWLKDGRPLPADSRWTKR 275
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
IS L T++ Y CE TN+ + + + V P LK GI
Sbjct: 276 ITGLTISDLR--TEDSGTYICEVTNT-----FGSAEATGILMVIDPLHVTLTPKKLKTGI 328
Query: 135 EATLICDSA-SSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIIS 185
+T+I A + +P T+ W+R N + + + G+ NE L+I+
Sbjct: 329 GSTVILSCALTGSPEFTIRWYR------NTELVLPDEAISIRGLSNETLLIT 374
Score = 37.5 bits (83), Expect = 0.19
Identities = 36/160 (22%), Positives = 59/160 (36%), Gaps = 16/160 (10%)
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ WE+ I P+ F + Y I K + L ++C+ + T+Q +
Sbjct: 159 VSWEKDTVSIIPEHRFFITYHGGLY-ISDVQKEDALSTYRCITKHKYSGETRQSNGARLS 217
Query: 354 FKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
++ P + + G L C P P+ W K+G LP A+
Sbjct: 218 VTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLP--------AD 269
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
IT L I+++ T D G+Y C N G + T
Sbjct: 270 SRWTKRIT---GLTISDLRTEDSGTYICEVTNTFGSAEAT 306
Score = 33.5 bits (73), Expect = 3.2
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 242 AVNSQGAAVANISVSVH----YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
AV S G ++ V++ PA I S V +D L C ++G+P A +KW
Sbjct: 1267 AVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP--APAVKWT 1324
Query: 298 RKGYKIDPKSVTFEPKNL---TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
K + V+ + L L++R K+E+ G + C N G V L+V+
Sbjct: 1325 -KDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATN-TGGFDTIIVNLLVQV 1382
Query: 355 KPEMDTSPNFVKSASNV 371
P+ SAS++
Sbjct: 1383 PPDQPRLTVSKTSASSI 1399
Score = 33.5 bits (73), Expect = 3.2
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P+ WTKD G+ I + G++L + + D+G YTC A N+ G
Sbjct: 1317 PAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLL-LRAVKAEDSGYYTCTATNTGGFDTII 1375
Query: 253 ISVSVHYP 260
+++ V P
Sbjct: 1376 VNLLVQVP 1383
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 81.8 bits (193), Expect = 9e-15
Identities = 86/372 (23%), Positives = 147/372 (39%), Gaps = 16/372 (4%)
Query: 186 VRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNS 245
V + G+ P I TW KDG I S + + ++ L +H+ G YTC A N+
Sbjct: 657 VVSSGDMP-IRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSL-KHN-GNYTCIASNA 713
Query: 246 QGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNP---LLAEHIKWERKGYK 302
+ V P N + VL+C+ G P ++ +H K +
Sbjct: 714 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 773
Query: 303 IDPKSVTFEPKNL-TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
P +T + L S L+IR E++G + C +NG+G+ + + L VK + +
Sbjct: 774 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSH 833
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
PN + + G L C + W K + + +Y A K++ S
Sbjct: 834 PN--TTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRY-AIATKDNGDEVVST 890
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L + D + C A N G ++L V PD L + V ++ L W
Sbjct: 891 LKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDP-PELEIREVKARSMNLRWTQR 949
Query: 482 FDG-GLQSWYRIRYRKVFDDSYKYEDV---LPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
FDG + + + I Y+ DS+ ++ + + L + Y + + NKIG
Sbjct: 950 FDGNSIITGFDIEYKNK-SDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIG 1008
Query: 538 QSKYRPDDTKAT 549
+S+ + T +T
Sbjct: 1009 RSEPSKELTIST 1020
Score = 81.0 bits (191), Expect = 2e-14
Identities = 76/306 (24%), Positives = 120/306 (39%), Gaps = 16/306 (5%)
Query: 188 ADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQ 246
A G P P+I W KDG P+ S R + L ++ L D+G Y CE N+
Sbjct: 288 ASGYPIPAIR--WLKDGRPLPADS------RWTKRITGLTISDLRTEDSGTYICEVTNTF 339
Query: 247 GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
G+A A + V P + + + +LSC G+P I+W R + P
Sbjct: 340 GSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFT--IRWYRNTELVLPD 397
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
L+I A+ + G +QC + T QD +I +F +
Sbjct: 398 EAISIRGLSNETLLITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGTPRIVSSFSE 455
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
N G+ LMC K P P+ TW+ + + V + ++ +D T S + +
Sbjct: 456 KVVNPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHRTNQYTMSDGTT-ISHMNVTG 513
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT-HSTVTLEWVPGFDGG 485
D G Y C ARN +G + +++V P +T V T+ V G+
Sbjct: 514 PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYY 573
Query: 486 LQSWYR 491
WY+
Sbjct: 574 SIKWYK 579
Score = 72.5 bits (170), Expect = 6e-12
Identities = 52/167 (31%), Positives = 77/167 (46%), Gaps = 11/167 (6%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
RL C PAP+ W+K+ + S H N LL+ V D G Y
Sbjct: 1347 RLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN------GTLLLRAVKAEDSGYY 1400
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRY 494
C A N GF T V L V PDQ LTV+ + S++TL W+PG +GG + ++Y
Sbjct: 1401 TCTATNTGGFDTIIVNLLVQVPPDQ-PRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1459
Query: 495 RKVFDDSYKYEDV-LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
D+S +++DV + +F + L+ T Y + A N +G +
Sbjct: 1460 S--VDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1504
Score = 50.0 bits (114), Expect = 3e-05
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 5/124 (4%)
Query: 38 GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNV-TDNQAQYRCE 96
G+ L+C TG +P T+ W++N + + + + +S E ++T+ + Y+C
Sbjct: 368 GSTVILSCALTG-SPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 426
Query: 97 ATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRD 156
AT A F + L P V +E V+ PG + +L+C +A PP T++W D
Sbjct: 427 ATRKAQTAQDFAIIALE-DGTPRIVSSFSE-KVVNPGEQFSLMC-AAKGAPPPTVTWALD 483
Query: 157 GIPV 160
P+
Sbjct: 484 DEPI 487
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 16 SPSDPP-SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDK 74
S +DP S P I + AG +L C ++G P+ + W K+ + + + ++ T +
Sbjct: 256 SVTDPAESIPTILDGFHSQEVWAGHTVELPCTASG-YPIPAIRWLKDGRPLPADSRWTKR 314
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
IS L T++ Y CE TN+ + + + V P LK GI
Sbjct: 315 ITGLTISDLR--TEDSGTYICEVTNT-----FGSAEATGILMVIDPLHVTLTPKKLKTGI 367
Query: 135 EATLICDSA-SSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIIS 185
+T+I A + +P T+ W+R N + + + G+ NE L+I+
Sbjct: 368 GSTVILSCALTGSPEFTIRWYR------NTELVLPDEAISIRGLSNETLLIT 413
Score = 38.3 bits (85), Expect = 0.11
Identities = 36/160 (22%), Positives = 60/160 (37%), Gaps = 16/160 (10%)
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+ WE+ I P++ F + Y I K + L ++C+ + T+Q +
Sbjct: 198 VSWEKDTVSIIPENRFFITYHGGLY-ISDVQKEDALSTYRCITKHKYSGETRQSNGARLS 256
Query: 354 FKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
++ P + + G L C P P+ W K+G LP A+
Sbjct: 257 VTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLP--------AD 308
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
IT L I+++ T D G+Y C N G + T
Sbjct: 309 SRWTKRIT---GLTISDLRTEDSGTYICEVTNTFGSAEAT 345
Score = 33.5 bits (73), Expect = 3.2
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 242 AVNSQGAAVANISVSVH----YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWE 297
AV S G ++ V++ PA I S V +D L C ++G+P A +KW
Sbjct: 1306 AVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP--APAVKWT 1363
Query: 298 RKGYKIDPKSVTFEPKNL---TSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
K + V+ + L L++R K+E+ G + C N G V L+V+
Sbjct: 1364 -KDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATN-TGGFDTIIVNLLVQV 1421
Query: 355 KPEMDTSPNFVKSASNV 371
P+ SAS++
Sbjct: 1422 PPDQPRLTVSKTSASSI 1438
Score = 33.5 bits (73), Expect = 3.2
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P+ WTKD G+ I + G++L + + D+G YTC A N+ G
Sbjct: 1356 PAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLL-LRAVKAEDSGYYTCTATNTGGFDTII 1414
Query: 253 ISVSVHYP 260
+++ V P
Sbjct: 1415 VNLLVQVP 1422
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 81.4 bits (192), Expect = 1e-14
Identities = 107/425 (25%), Positives = 170/425 (40%), Gaps = 42/425 (9%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + T N V E + RA+GNP P I+ W +G+PI + + +
Sbjct: 336 VRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNPKPRIS--WLTNGVPI-EIAPDDPSR 391
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV--HYPAGIKSVSQNVVANP 274
+I +G + + + + +Y C A N G +AN V+V P + +
Sbjct: 392 KI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIA 449
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N A+L C G+PL I+W KG K + L I A+ ++ G + C
Sbjct: 450 NRPALLDCAFFGSPLPT--IEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 506
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WS 392
V N +G A K +V L +K + P + + G + CK K S T W
Sbjct: 507 VARNKLGMA-KNEVHLEIKDATWIVKQPEY--AVVQRGSMVSFECKVKHDHTLSLTVLWL 563
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ +LP S + F DH L++ +V+ D G+Y C A L + + L
Sbjct: 564 KDNRELP---SDERFTV--DKDH------LVVADVSDDDSGTYTCVANTTLDSVSASAVL 612
Query: 453 DVTS----------APDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDS 501
V + P+ L +T+ +V L W PG D + + I Y
Sbjct: 613 SVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKP 672
Query: 502 YKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELS 560
+ T T L +Y F VMA+N IG+S P + LT + + +
Sbjct: 673 GLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKS--LPSEASEQYLTKASEPDKN 730
Query: 561 TVSTE 565
+ E
Sbjct: 731 PTAVE 735
Score = 71.7 bits (168), Expect = 1e-11
Identities = 74/287 (25%), Positives = 114/287 (39%), Gaps = 22/287 (7%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDG-LPITQSSYSSGNDRIISEGSMLNMTKLT 231
N + L + A+G P I Y +DG LP ++ Y + L + ++
Sbjct: 260 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE-------KTLQIIHVS 312
Query: 232 RHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA 291
D+G Y C A N+ GA ISV V + QN+V +P ED L C A GNP
Sbjct: 313 EADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNP--K 370
Query: 292 EHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI 351
I W G I+ K +I + + +QC +N G + +
Sbjct: 371 PRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV 430
Query: 352 VKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
+ P + T N + + L C P P+ W K G K + H
Sbjct: 431 LAEPPRILTPANTLYQVI-ANRPALLDCAFFGSPLPTIEWFK-GAK---------GSALH 479
Query: 412 KNDHITYTSVLLINNVATSD-YGSYECGARNELGFSTTTVKLDVTSA 457
++ ++ + + L VA D G+Y C ARN+LG + V L++ A
Sbjct: 480 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDA 526
Score = 67.3 bits (157), Expect = 2e-10
Identities = 69/266 (25%), Positives = 113/266 (42%), Gaps = 21/266 (7%)
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
VLS I L I W ++ + PK+ T KN L I + GN+QC+ N
Sbjct: 268 VLSLECIAEGLPTPIIYWAKEDGML-PKNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKN 325
Query: 339 GIGSATKQDVMLIVKFKPEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
+G A + + VK P T+P N V S G+ G L+C+ P P +W NGV
Sbjct: 326 ALG-AIHHTISVRVKAAPYWITAPQNLVLSP---GEDGTLICRANGNPKPRISWLTNGVP 381
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
+ + K D T ++ +NV Y+C A NE G+ ++V +
Sbjct: 382 IEIAPDDPS----RKIDGDT----IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 433
Query: 458 PDQVV--SLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHAT-N 514
P +++ + T+ V + L F L + I + K S +ED+ H
Sbjct: 434 PPRILTPANTLYQVIANRPALLDCAFFGSPLPT---IEWFKGAKGSALHEDIYVLHENGT 490
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
+ +K++ ++ +A NK+G +K
Sbjct: 491 LEIPVAQKDSTGTYTCVARNKLGMAK 516
Score = 62.9 bits (146), Expect = 5e-09
Identities = 78/302 (25%), Positives = 125/302 (41%), Gaps = 44/302 (14%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGL-------PITQSSYSSGN--DRIISEGSMLNMTKL 230
E ++I A G PP +++WT++G P+ +G I+SEG K
Sbjct: 62 ENIVIQCEAKGKPPP-SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG------KA 114
Query: 231 TRHDAGIYTCEAVNSQGAAVANISV--SVHYPAGIKSVSQNVVANPNEDAVLSCTA-IGN 287
++ G+Y C A N +GAAV+N V P K + + + VL C IG
Sbjct: 115 ETYE-GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 288 PLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLG-NFQCVV--NNGIGSAT 344
P I W ++ P+S + L L E+ ++ C N+
Sbjct: 174 P--PPIIFWMDNSFQRLPQSERVS-QGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQ 230
Query: 345 KQDVML-IVKFKPEMDTSPNFVKSASNV-------GQVGRLMCKCKSVPAPSFTWSKNGV 396
KQ + + ++ K + P F+ N G V L C + +P P W+K
Sbjct: 231 KQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDG 290
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
LP N + +KN + L I +V+ +D G+Y+C A+N LG T+ + V +
Sbjct: 291 MLPKNRTV------YKN----FEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 340
Query: 457 AP 458
AP
Sbjct: 341 AP 342
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Query: 15 NSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDK 74
+S PP+ G G V L CI+ G P + W K D + +T K
Sbjct: 243 SSRERPPTFLTPEGNASNKEELRGNVLSLECIAEG-LPTPIIYWAKEDGMLPKN-RTVYK 300
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
+ I+ + Y+C A N+ I T+++ V AP + + VL PG
Sbjct: 301 NFEKTLQIIHVSEADSGNYQCIAKNALGAI--HHTISVRVKAAPYWITA-PQNLVLSPGE 357
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAP 164
+ TLIC A+ NP +SW +G+P++ AP
Sbjct: 358 DGTLIC-RANGNPKPRISWLTNGVPIEIAP 386
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 17/159 (10%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV----L 508
V SAP SL + N T ++TLEW P G+ + Y ++Y+ + + +++ + +
Sbjct: 932 VPSAPS---SLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPI-NSTHELGPLVDLKI 987
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATT----LTSSEVGELSTVST 564
P + T +T+ L +T Y F A G ++ T + +VG +++
Sbjct: 988 PANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKAMAS 1047
Query: 565 EYVETPDISKPVIVYVSLTGAVLVLINVALIACFVWKRR 603
V DI+ ++ L AV +LI + LI CF+ + +
Sbjct: 1048 RQV---DIATQG-WFIGLMCAVALLILILLIVCFIRRNK 1082
Score = 39.5 bits (88), Expect = 0.048
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 257 VHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG--YKIDPKS-VTFEPK 313
V P + ++ + +P E+ V+ C A G P W R G + ID VT +P
Sbjct: 43 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKP--PPSFSWTRNGTHFDIDKDPLVTMKPG 100
Query: 314 NLTSYL-IIRKAKSENL-GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV 371
T + I+ + K+E G +QC N G+A ++++ P + T
Sbjct: 101 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP-LWTKEKLEPITLQS 159
Query: 372 GQVGRLMCKCK-SVPAPSFTWSKNGV-KLP 399
GQ L C+ +P P W N +LP
Sbjct: 160 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLP 189
Score = 32.3 bits (70), Expect = 7.3
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTD-NQAQY 93
L+ G L C GNP ++W N I + + + I +NV + + A Y
Sbjct: 353 LSPGEDGTLIC-RANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVY 411
Query: 94 RCEATN 99
+C A+N
Sbjct: 412 QCNASN 417
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 81.4 bits (192), Expect = 1e-14
Identities = 107/425 (25%), Positives = 170/425 (40%), Gaps = 42/425 (9%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + T N V E + RA+GNP P I+ W +G+PI + + +
Sbjct: 336 VRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNPKPRIS--WLTNGVPI-EIAPDDPSR 391
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV--HYPAGIKSVSQNVVANP 274
+I +G + + + + +Y C A N G +AN V+V P + +
Sbjct: 392 KI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIA 449
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N A+L C G+PL I+W KG K + L I A+ ++ G + C
Sbjct: 450 NRPALLDCAFFGSPLPT--IEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 506
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WS 392
V N +G A K +V L +K + P + + G + CK K S T W
Sbjct: 507 VARNKLGMA-KNEVHLEIKDATWIVKQPEY--AVVQRGSMVSFECKVKHDHTLSLTVLWL 563
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ +LP S + F DH L++ +V+ D G+Y C A L + + L
Sbjct: 564 KDNRELP---SDERFTV--DKDH------LVVADVSDDDSGTYTCVANTTLDSVSASAVL 612
Query: 453 DVTS----------APDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDS 501
V + P+ L +T+ +V L W PG D + + I Y
Sbjct: 613 SVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKP 672
Query: 502 YKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELS 560
+ T T L +Y F VMA+N IG+S P + LT + + +
Sbjct: 673 GLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKS--LPSEASEQYLTKASEPDKN 730
Query: 561 TVSTE 565
+ E
Sbjct: 731 PTAVE 735
Score = 71.7 bits (168), Expect = 1e-11
Identities = 74/287 (25%), Positives = 114/287 (39%), Gaps = 22/287 (7%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDG-LPITQSSYSSGNDRIISEGSMLNMTKLT 231
N + L + A+G P I Y +DG LP ++ Y + L + ++
Sbjct: 260 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE-------KTLQIIHVS 312
Query: 232 RHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA 291
D+G Y C A N+ GA ISV V + QN+V +P ED L C A GNP
Sbjct: 313 EADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNP--K 370
Query: 292 EHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI 351
I W G I+ K +I + + +QC +N G + +
Sbjct: 371 PRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV 430
Query: 352 VKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
+ P + T N + + L C P P+ W K G K + H
Sbjct: 431 LAEPPRILTPANTLYQVI-ANRPALLDCAFFGSPLPTIEWFK-GAK---------GSALH 479
Query: 412 KNDHITYTSVLLINNVATSD-YGSYECGARNELGFSTTTVKLDVTSA 457
++ ++ + + L VA D G+Y C ARN+LG + V L++ A
Sbjct: 480 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDA 526
Score = 67.3 bits (157), Expect = 2e-10
Identities = 69/266 (25%), Positives = 113/266 (42%), Gaps = 21/266 (7%)
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
VLS I L I W ++ + PK+ T KN L I + GN+QC+ N
Sbjct: 268 VLSLECIAEGLPTPIIYWAKEDGML-PKNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKN 325
Query: 339 GIGSATKQDVMLIVKFKPEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
+G A + + VK P T+P N V S G+ G L+C+ P P +W NGV
Sbjct: 326 ALG-AIHHTISVRVKAAPYWITAPQNLVLSP---GEDGTLICRANGNPKPRISWLTNGVP 381
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
+ + K D T ++ +NV Y+C A NE G+ ++V +
Sbjct: 382 IEIAPDDPS----RKIDGDT----IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 433
Query: 458 PDQVV--SLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHAT-N 514
P +++ + T+ V + L F L + I + K S +ED+ H
Sbjct: 434 PPRILTPANTLYQVIANRPALLDCAFFGSPLPT---IEWFKGAKGSALHEDIYVLHENGT 490
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
+ +K++ ++ +A NK+G +K
Sbjct: 491 LEIPVAQKDSTGTYTCVARNKLGMAK 516
Score = 62.9 bits (146), Expect = 5e-09
Identities = 78/302 (25%), Positives = 125/302 (41%), Gaps = 44/302 (14%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGL-------PITQSSYSSGN--DRIISEGSMLNMTKL 230
E ++I A G PP +++WT++G P+ +G I+SEG K
Sbjct: 62 ENIVIQCEAKGKPPP-SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG------KA 114
Query: 231 TRHDAGIYTCEAVNSQGAAVANISV--SVHYPAGIKSVSQNVVANPNEDAVLSCTA-IGN 287
++ G+Y C A N +GAAV+N V P K + + + VL C IG
Sbjct: 115 ETYE-GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 288 PLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLG-NFQCVV--NNGIGSAT 344
P I W ++ P+S + L L E+ ++ C N+
Sbjct: 174 P--PPIIFWMDNSFQRLPQSERVS-QGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQ 230
Query: 345 KQDVML-IVKFKPEMDTSPNFVKSASNV-------GQVGRLMCKCKSVPAPSFTWSKNGV 396
KQ + + ++ K + P F+ N G V L C + +P P W+K
Sbjct: 231 KQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDG 290
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
LP N + +KN + L I +V+ +D G+Y+C A+N LG T+ + V +
Sbjct: 291 MLPKNRTV------YKN----FEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 340
Query: 457 AP 458
AP
Sbjct: 341 AP 342
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Query: 15 NSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDK 74
+S PP+ G G V L CI+ G P + W K D + +T K
Sbjct: 243 SSRERPPTFLTPEGNASNKEELRGNVLSLECIAEG-LPTPIIYWAKEDGMLPKN-RTVYK 300
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGI 134
+ I+ + Y+C A N+ I T+++ V AP + + VL PG
Sbjct: 301 NFEKTLQIIHVSEADSGNYQCIAKNALGAI--HHTISVRVKAAPYWITA-PQNLVLSPGE 357
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAP 164
+ TLIC A+ NP +SW +G+P++ AP
Sbjct: 358 DGTLIC-RANGNPKPRISWLTNGVPIEIAP 386
Score = 39.5 bits (88), Expect = 0.048
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 257 VHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG--YKIDPKS-VTFEPK 313
V P + ++ + +P E+ V+ C A G P W R G + ID VT +P
Sbjct: 43 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKP--PPSFSWTRNGTHFDIDKDPLVTMKPG 100
Query: 314 NLTSYL-IIRKAKSENL-GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV 371
T + I+ + K+E G +QC N G+A ++++ P + T
Sbjct: 101 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP-LWTKEKLEPITLQS 159
Query: 372 GQVGRLMCKCK-SVPAPSFTWSKNGV-KLP 399
GQ L C+ +P P W N +LP
Sbjct: 160 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLP 189
Score = 38.7 bits (86), Expect = 0.084
Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 21/155 (13%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV----L 508
V SAP SL + N T ++TLEW P G+ + Y ++Y+ + + +++ + +
Sbjct: 932 VPSAPS---SLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPI-NSTHELGPLVDLKI 987
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVE 568
P + T +T+ L +T Y F A G ++ TT+ + ++T+
Sbjct: 988 PANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA-VTTVDEAMASRQVDIATQG-- 1044
Query: 569 TPDISKPVIVYVSLTGAVLVLINVALIACFVWKRR 603
++ L AV +LI + LI CF+ + +
Sbjct: 1045 ---------WFIGLMCAVALLILILLIVCFIRRNK 1070
Score = 32.3 bits (70), Expect = 7.3
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 35 LAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVTD-NQAQY 93
L+ G L C GNP ++W N I + + + I +NV + + A Y
Sbjct: 353 LSPGEDGTLIC-RANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVY 411
Query: 94 RCEATN 99
+C A+N
Sbjct: 412 QCNASN 417
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus
protein.
Length = 1236
Score = 81.4 bits (192), Expect = 1e-14
Identities = 107/425 (25%), Positives = 170/425 (40%), Gaps = 42/425 (9%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + T N V E + RA+GNP P I+ W +G+PI + + +
Sbjct: 355 VRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNPKPRIS--WLTNGVPI-EIAPDDPSR 410
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV--HYPAGIKSVSQNVVANP 274
+I +G + + + + +Y C A N G +AN V+V P + +
Sbjct: 411 KI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIA 468
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N A+L C G+PL I+W KG K + L I A+ ++ G + C
Sbjct: 469 NRPALLDCAFFGSPLPT--IEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 525
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WS 392
V N +G A K +V L +K + P + + G + CK K S T W
Sbjct: 526 VARNKLGMA-KNEVHLEIKDPTWIVKQPEY--AVVQRGSMVSFECKVKHDHTLSLTVLWL 582
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ +LP S + F DH L++ +V+ D G+Y C A L + + L
Sbjct: 583 KDNRELP---SDERFTV--DKDH------LVVADVSDDDSGTYTCVANTTLDSVSASAVL 631
Query: 453 DVTS----------APDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDS 501
V + P+ L +T+ +V L W PG D + + I Y
Sbjct: 632 SVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKP 691
Query: 502 YKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELS 560
+ T T L +Y F VMA+N IG+S P + LT + + +
Sbjct: 692 GLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKS--LPSEASEQYLTKASEPDKN 749
Query: 561 TVSTE 565
+ E
Sbjct: 750 PTAVE 754
Score = 71.3 bits (167), Expect = 1e-11
Identities = 101/427 (23%), Positives = 163/427 (38%), Gaps = 46/427 (10%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVT--DNQA 91
TL +G L C G P + W N + ++ + ++ ++ +NV D +
Sbjct: 156 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDL-YFSNVLPEDTRE 214
Query: 92 QYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSN--PPA 149
Y C A + T+ T+ + + + V D + + T + SS PP
Sbjct: 215 DYICYARFNHTQ-----TIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPT 269
Query: 150 TLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDG-LPITQ 208
L+ P NA N + L + A+G P I Y +DG LP +
Sbjct: 270 FLT------PEGNAS--------NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNR 315
Query: 209 SSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ 268
+ Y + L + ++ D+G Y C A N+ GA ISV V + Q
Sbjct: 316 TVYKNFE-------KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQ 368
Query: 269 NVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
N+V +P ED L C A GNP I W G I+ K +I + +
Sbjct: 369 NLVLSPGEDGTLICRANGNP--KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 426
Query: 329 LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
+QC +N G + ++ P + T N + + L C P P+
Sbjct: 427 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVI-ANRPALLDCAFFGSPLPT 485
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD-YGSYECGARNELGFST 447
W K G K + H++ ++ + + L VA D G+Y C ARN+LG +
Sbjct: 486 IEWFK-GAK---------GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAK 535
Query: 448 TTVKLDV 454
V L++
Sbjct: 536 NEVHLEI 542
Score = 67.3 bits (157), Expect = 2e-10
Identities = 69/266 (25%), Positives = 113/266 (42%), Gaps = 21/266 (7%)
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
VLS I L I W ++ + PK+ T KN L I + GN+QC+ N
Sbjct: 287 VLSLECIAEGLPTPIIYWAKEDGML-PKNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKN 344
Query: 339 GIGSATKQDVMLIVKFKPEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
+G A + + VK P T+P N V S G+ G L+C+ P P +W NGV
Sbjct: 345 ALG-AIHHTISVRVKAAPYWITAPQNLVLSP---GEDGTLICRANGNPKPRISWLTNGVP 400
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
+ + K D T ++ +NV Y+C A NE G+ ++V +
Sbjct: 401 IEIAPDDPS----RKIDGDT----IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 452
Query: 458 PDQVV--SLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHAT-N 514
P +++ + T+ V + L F L + I + K S +ED+ H
Sbjct: 453 PPRILTPANTLYQVIANRPALLDCAFFGSPLPT---IEWFKGAKGSALHEDIYVLHENGT 509
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
+ +K++ ++ +A NK+G +K
Sbjct: 510 LEIPVAQKDSTGTYTCVARNKLGMAK 535
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 10/87 (11%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V L C + +P P W+K LP N + +KN + L I +V+ +D
Sbjct: 285 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTV------YKN----FEKTLQIIHVSEAD 334
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAP 458
G+Y+C A+N LG T+ + V +AP
Sbjct: 335 SGNYQCIAKNALGAIHHTISVRVKAAP 361
Score = 39.5 bits (88), Expect = 0.048
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 257 VHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG--YKIDPKS-VTFEPK 313
V P + ++ + +P E+ V+ C A G P W R G + ID VT +P
Sbjct: 43 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKP--PPSFSWTRNGTHFDIDKDPLVTMKPG 100
Query: 314 NLTSYL-IIRKAKSENL-GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV 371
T + I+ + K+E G +QC N G+A ++++ P + T
Sbjct: 101 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP-LWTKEKLEPITLQS 159
Query: 372 GQVGRLMCKCK-SVPAPSFTWSKNGV-KLP 399
GQ L C+ +P P W N +LP
Sbjct: 160 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLP 189
Score = 36.7 bits (81), Expect = 0.34
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
+ C+ K P PSF+W++NG ++ K T ++ A + G Y+
Sbjct: 66 IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM---KPGTGTLIINIMSEGKAETYEGVYQ 122
Query: 437 CGARNELG 444
C ARNE G
Sbjct: 123 CTARNERG 130
Score = 35.1 bits (77), Expect = 1.0
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGL-------PITQSSYSSGN--DRIISEGSMLNMTKL 230
E ++I A G PP +++WT++G P+ +G I+SEG K
Sbjct: 62 ENIVIQCEAKGKPPP-SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG------KA 114
Query: 231 TRHDAGIYTCEAVNSQGAAVANISV--SVHYPAGIKSVSQNVVANPNEDAVLSC-TAIGN 287
++ G+Y C A N +GAAV+N V P K + + + VL C IG
Sbjct: 115 ETYE-GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 288 P 288
P
Sbjct: 174 P 174
Score = 33.9 bits (74), Expect = 2.4
Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 9/101 (8%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV----L 508
V SAP SL + N T ++TLEW P G+ + Y ++Y+ + + +++ + +
Sbjct: 951 VPSAPS---SLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPI-NSTHELGPLVDLKI 1006
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
P + T +T+ L +T Y F A G ++ T
Sbjct: 1007 PANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1047
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 81.4 bits (192), Expect = 1e-14
Identities = 107/425 (25%), Positives = 170/425 (40%), Gaps = 42/425 (9%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + T N V E + RA+GNP P I+ W +G+PI + + +
Sbjct: 355 VRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNPKPRIS--WLTNGVPI-EIAPDDPSR 410
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV--HYPAGIKSVSQNVVANP 274
+I +G + + + + +Y C A N G +AN V+V P + +
Sbjct: 411 KI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIA 468
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N A+L C G+PL I+W KG K + L I A+ ++ G + C
Sbjct: 469 NRPALLDCAFFGSPLPT--IEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 525
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WS 392
V N +G A K +V L +K + P + + G + CK K S T W
Sbjct: 526 VARNKLGMA-KNEVHLEIKDPTWIVKQPEY--AVVQRGSMVSFECKVKHDHTLSLTVLWL 582
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ +LP S + F DH L++ +V+ D G+Y C A L + + L
Sbjct: 583 KDNRELP---SDERFTV--DKDH------LVVADVSDDDSGTYTCVANTTLDSVSASAVL 631
Query: 453 DVTS----------APDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDS 501
V + P+ L +T+ +V L W PG D + + I Y
Sbjct: 632 SVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKP 691
Query: 502 YKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELS 560
+ T T L +Y F VMA+N IG+S P + LT + + +
Sbjct: 692 GLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKS--LPSEASEQYLTKASEPDKN 749
Query: 561 TVSTE 565
+ E
Sbjct: 750 PTAVE 754
Score = 71.3 bits (167), Expect = 1e-11
Identities = 101/427 (23%), Positives = 163/427 (38%), Gaps = 46/427 (10%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVT--DNQA 91
TL +G L C G P + W N + ++ + ++ ++ +NV D +
Sbjct: 156 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDL-YFSNVLPEDTRE 214
Query: 92 QYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSN--PPA 149
Y C A + T+ T+ + + + V D + + T + SS PP
Sbjct: 215 DYICYARFNHTQ-----TIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPT 269
Query: 150 TLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDG-LPITQ 208
L+ P NA N + L + A+G P I Y +DG LP +
Sbjct: 270 FLT------PEGNAS--------NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNR 315
Query: 209 SSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ 268
+ Y + L + ++ D+G Y C A N+ GA ISV V + Q
Sbjct: 316 TVYKNFE-------KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQ 368
Query: 269 NVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
N+V +P ED L C A GNP I W G I+ K +I + +
Sbjct: 369 NLVLSPGEDGTLICRANGNP--KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 426
Query: 329 LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
+QC +N G + ++ P + T N + + L C P P+
Sbjct: 427 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVI-ANRPALLDCAFFGSPLPT 485
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD-YGSYECGARNELGFST 447
W K G K + H++ ++ + + L VA D G+Y C ARN+LG +
Sbjct: 486 IEWFK-GAK---------GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAK 535
Query: 448 TTVKLDV 454
V L++
Sbjct: 536 NEVHLEI 542
Score = 67.3 bits (157), Expect = 2e-10
Identities = 69/266 (25%), Positives = 113/266 (42%), Gaps = 21/266 (7%)
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
VLS I L I W ++ + PK+ T KN L I + GN+QC+ N
Sbjct: 287 VLSLECIAEGLPTPIIYWAKEDGML-PKNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKN 344
Query: 339 GIGSATKQDVMLIVKFKPEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
+G A + + VK P T+P N V S G+ G L+C+ P P +W NGV
Sbjct: 345 ALG-AIHHTISVRVKAAPYWITAPQNLVLSP---GEDGTLICRANGNPKPRISWLTNGVP 400
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
+ + K D T ++ +NV Y+C A NE G+ ++V +
Sbjct: 401 IEIAPDDPS----RKIDGDT----IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 452
Query: 458 PDQVV--SLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHAT-N 514
P +++ + T+ V + L F L + I + K S +ED+ H
Sbjct: 453 PPRILTPANTLYQVIANRPALLDCAFFGSPLPT---IEWFKGAKGSALHEDIYVLHENGT 509
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
+ +K++ ++ +A NK+G +K
Sbjct: 510 LEIPVAQKDSTGTYTCVARNKLGMAK 535
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 10/87 (11%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V L C + +P P W+K LP N + +KN + L I +V+ +D
Sbjct: 285 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTV------YKN----FEKTLQIIHVSEAD 334
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAP 458
G+Y+C A+N LG T+ + V +AP
Sbjct: 335 SGNYQCIAKNALGAIHHTISVRVKAAP 361
Score = 39.5 bits (88), Expect = 0.048
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 257 VHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG--YKIDPKS-VTFEPK 313
V P + ++ + +P E+ V+ C A G P W R G + ID VT +P
Sbjct: 43 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKP--PPSFSWTRNGTHFDIDKDPLVTMKPG 100
Query: 314 NLTSYL-IIRKAKSENL-GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV 371
T + I+ + K+E G +QC N G+A ++++ P + T
Sbjct: 101 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP-LWTKEKLEPITLQS 159
Query: 372 GQVGRLMCKCK-SVPAPSFTWSKNGV-KLP 399
GQ L C+ +P P W N +LP
Sbjct: 160 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLP 189
Score = 36.7 bits (81), Expect = 0.34
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
+ C+ K P PSF+W++NG ++ K T ++ A + G Y+
Sbjct: 66 IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM---KPGTGTLIINIMSEGKAETYEGVYQ 122
Query: 437 CGARNELG 444
C ARNE G
Sbjct: 123 CTARNERG 130
Score = 35.1 bits (77), Expect = 1.0
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGL-------PITQSSYSSGN--DRIISEGSMLNMTKL 230
E ++I A G PP +++WT++G P+ +G I+SEG K
Sbjct: 62 ENIVIQCEAKGKPPP-SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG------KA 114
Query: 231 TRHDAGIYTCEAVNSQGAAVANISV--SVHYPAGIKSVSQNVVANPNEDAVLSC-TAIGN 287
++ G+Y C A N +GAAV+N V P K + + + VL C IG
Sbjct: 115 ETYE-GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 288 P 288
P
Sbjct: 174 P 174
Score = 33.9 bits (74), Expect = 2.4
Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 9/101 (8%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV----L 508
V SAP SL + N T ++TLEW P G+ + Y ++Y+ + + +++ + +
Sbjct: 951 VPSAPS---SLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPI-NSTHELGPLVDLKI 1006
Query: 509 PKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
P + T +T+ L +T Y F A G ++ T
Sbjct: 1007 PANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1047
>DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 81.0 bits (191), Expect = 2e-14
Identities = 92/363 (25%), Positives = 154/363 (42%), Gaps = 32/363 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 192 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 248
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 249 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 306
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K K + +
Sbjct: 307 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVKDATQITQGPRSTIE 361
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 362 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 412
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 413 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 472
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + + +P + T+ T+ L Y F V AINK G +
Sbjct: 473 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 531
Query: 541 YRP 543
P
Sbjct: 532 PSP 534
Score = 68.5 bits (160), Expect = 9e-11
Identities = 78/326 (23%), Positives = 124/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P + +Y + N
Sbjct: 75 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN-------K 127
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 128 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 187
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 188 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 245
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 246 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 302
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L V A
Sbjct: 303 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 354
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 355 GPRSTIEKKGSRVTFTCQASFDPSLQ 380
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 81.0 bits (191), Expect = 2e-14
Identities = 83/316 (26%), Positives = 131/316 (41%), Gaps = 17/316 (5%)
Query: 264 KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTF---EPKNLTSYLI 320
K +N+ +A L C G+P +KW R+G +I + + E K LI
Sbjct: 24434 KEELRNLNVRYQSNATLVCKVTGHP--KPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 24491
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLI-VKFKPEMDTSPNFVKSASNV-GQVGRLM 378
I ++ +Q N GS + + + V K + + + + + G+V +
Sbjct: 24492 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIK 24551
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
P P TW K G L ++ + Y ++ +TS++ N V D G Y
Sbjct: 24552 IPFSGKPDPVITWQK-GQDL-IDNNGHYQVIVTRS----FTSLVFPNGVERKDAGFYVVC 24605
Query: 439 ARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
A+N G TV+LDV PD + V++V+ +V L W P DGG + I K
Sbjct: 24606 AKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYI-VEKC 24664
Query: 498 FDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVG 557
+ ++ V T +TV L T Y F V+A NK G SK P + T+T +
Sbjct: 24665 ATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSK--PSEPSEPTITKEDKT 24722
Query: 558 ELSTVSTEYVETPDIS 573
E ET ++S
Sbjct: 24723 RAMNYDEEVDETREVS 24738
Score = 68.5 bits (160), Expect = 9e-11
Identities = 43/161 (26%), Positives = 77/161 (47%), Gaps = 8/161 (4%)
Query: 382 KSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARN 441
++VP P+ +W K+G ++ + KNDHI+ + L + +D G Y N
Sbjct: 7914 RAVPVPTVSWHKDGKEVKASDRLTM-----KNDHIS--AHLEVPKSVRADAGIYTITLEN 7966
Query: 442 ELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDD 500
+LG +T ++ + V P + +++T S+ L W P FDGG + + R+
Sbjct: 7967 KLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR 8026
Query: 501 SYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ ++ ++TV L N +Y F V A+NK+G +Y
Sbjct: 8027 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 8067
Score = 67.3 bits (157), Expect = 2e-10
Identities = 68/283 (24%), Positives = 107/283 (37%), Gaps = 14/283 (4%)
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK-IDPKSVTFEPKNLTSYLI 320
GI+ ++V E A LSC +G PL IKW R G + I + T L
Sbjct: 24037 GIRKEMKDVTTKLGEAAQLSCQIVGRPL--PDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCK 380
+ + E+ G + C+ N +G +L+ P K VG RL
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVM 24154
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
P P+ TW +G KL N+ +H YT +++ N + G Y+
Sbjct: 24155 YIGRPVPAMTWF-HGQKLLQNSEN---ITIENTEH--YTHLVMKNVQRKTHAGKYKVQLS 24208
Query: 441 NELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFD 499
N G + +++ PD+ + + + ++ + W P D G SW + +
Sbjct: 24209 NVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG-GSWITNYVVEKCE 24267
Query: 500 DSYKYEDVLPKHATNFT---VHGLEKNTDYIFSVMAINKIGQS 539
E L A + T + L +N Y F V A N G S
Sbjct: 24268 AKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGIS 24310
Score = 66.5 bits (155), Expect = 4e-10
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT-YTSVLLINNVATSDYGSY 435
++ K K VP P+ TW K K P N + + H N + T L+I SD G Y
Sbjct: 9639 IVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY-DTHVNKLVVDDTCTLVIPQSRRSDTGLY 9697
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRI 492
A N LG ++ ++L+V P V + +V+ +TL W P DGG + + Y I
Sbjct: 9698 TITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVI 9757
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ ++ + PK T +T+ L + +Y+F +MA NK G
Sbjct: 9758 EKREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMAQNKYG 9801
Score = 63.7 bits (148), Expect = 3e-09
Identities = 61/239 (25%), Positives = 101/239 (42%), Gaps = 18/239 (7%)
Query: 306 KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN--GIGS-ATKQDVMLIVK-FKPEMDTS 361
K T +T + ++ +++ NF+ N G+G A DV ++ + P+ +
Sbjct: 14224 KDTTGTALRITQF-VVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELD 14282
Query: 362 PNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
++ G R+ K PAP TW+K+ + L K A + T
Sbjct: 14283 AELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL------KNRANIENTESFT--- 14333
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-V 479
+L+I D G + N G + V + V P V++L T++T +VTL W +
Sbjct: 14334 LLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDL 14393
Query: 480 PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
P DGG + + Y + R+ SY H + V GL + +Y F VMA N+ G
Sbjct: 14394 PLIDGGSRITNYIVEKREATRKSYSTATT-KCHKCTYKVTGLSEGCEYFFRVMAENEYG 14451
Score = 63.3 bits (147), Expect = 3e-09
Identities = 61/226 (26%), Positives = 98/226 (43%), Gaps = 22/226 (9%)
Query: 356 PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P+++ + + K+ + G RLM P P TWSK G+ L D
Sbjct: 22947 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAII---------D 22997
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S+L+++ V D G Y A N+ G + TV + V P S+ V V+ +V
Sbjct: 22998 TTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSV 23057
Query: 475 TLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVM 531
T+ W +P DGG + Y + R+ ++K V K T + + GL + T Y F V+
Sbjct: 23058 TITWEIPTIDGGAPVNNYIVEKREAAMRAFK--TVTTKCSKTLYRISGLVEGTMYYFRVL 23115
Query: 532 AINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVI 577
N G + P +T L V E+ V + +E D++K +
Sbjct: 23116 PENIYGIGE--PCETSDAVL----VSEVPLVPAK-LEVVDVTKSTV 23154
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/170 (27%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
VGQ R++ + K P P TW+K G L + + + L I +
Sbjct: 11425 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE-------LQIKEAVRA 11477
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFD-GGLQ-S 488
D+G Y A+N G + + ++V P +L VTNVT T+ W D GG + +
Sbjct: 11478 DHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEIT 11537
Query: 489 WYRIRYRKVFDDSYKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIG 537
+ + YRK + K ++ T + L N +Y F V A NK+G
Sbjct: 11538 NFIVEYRK---PNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG 11584
Score = 61.7 bits (143), Expect = 1e-08
Identities = 53/200 (26%), Positives = 83/200 (41%), Gaps = 17/200 (8%)
Query: 356 PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D NF ++ G RL + P P+ WSK L + A+ H D
Sbjct: 21858 PELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR------ADIHTTD 21911
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S L + N +D G Y N G + T + V P +T +VT +
Sbjct: 21912 SF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSA 21968
Query: 475 TLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATN--FTVHGLEKNTDYIFSVM 531
TL W P DGG + + + ++ + S + V+ + T F V+ L + Y F V
Sbjct: 21969 TLMWDAPLLDGGARIHHYVVEKR--EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22026
Query: 532 AINK--IGQSKYRPDDTKAT 549
A+N+ +G+ P+ AT
Sbjct: 22027 AVNEYGVGEPYEMPEPIVAT 22046
Score = 60.9 bits (141), Expect = 2e-08
Identities = 63/236 (26%), Positives = 92/236 (38%), Gaps = 21/236 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFK-----PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVP 385
F+ N +G ++ +K K PE+D + K G RL + P
Sbjct: 12078 FRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRP 12137
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF 445
AP TW K G+ V + D + + L+I N D G Y N G
Sbjct: 12138 APKVTWRKVGIDNVVRKG--------QVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGE 12189
Query: 446 STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYK 503
V + V P V L V++VT ++ + W P DGG Q + Y + R+ D
Sbjct: 12190 KAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREA--DRKT 12247
Query: 504 YEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGE 558
+ V P+ T+F V L +Y F V A+N+ G P D L S + E
Sbjct: 12248 WSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGV--PTDVPKPVLASDPLSE 12301
Score = 59.7 bits (138), Expect = 4e-08
Identities = 58/226 (25%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 321 IRKAKSENLGNFQ-CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKSAS-NVGQV 374
+ K K NF+ C +N+ G+G ++ + + PE++ + K
Sbjct: 18568 VTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT 18627
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
RL K P P W K L + + F ++L+I+NV D G
Sbjct: 18628 LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSF---------TMLVIDNVTRFDSGR 18678
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRI 492
Y N G T V + V +P V+LT+ V +VTL W P DGG + + Y +
Sbjct: 18679 YNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIV 18738
Query: 493 RYRKVFDDSY-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ +Y + K T F + L++ Y F V+A N+ G
Sbjct: 18739 EKRETTRKAYATITNNCTK--TTFRIENLQEGCSYYFRVLASNEYG 18782
Score = 59.7 bits (138), Expect = 4e-08
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 15/189 (7%)
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT------VKLDVT 455
TST + H IT T + V ++Y + A+N++G S T+ V D
Sbjct: 23874 TSTDKWVR-HNKTQITTTMYTVTGLVPDAEY-QFRIIAQNDVGLSETSPASEPVVCKDPF 23931
Query: 456 SAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHAT 513
P Q L + +++ +VTL+W P DGG + Y + YR+ D ++K +
Sbjct: 23932 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 23991
Query: 514 NFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTK-ATTLTSSEV----GELSTVSTEYVE 568
FT+ GL + T+Y F V A N+ G S+ R T LTS E E+ V+T+ E
Sbjct: 23992 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGE 24051
Query: 569 TPDISKPVI 577
+S ++
Sbjct: 24052 AAQLSCQIV 24060
Score = 58.8 bits (136), Expect = 7e-08
Identities = 51/187 (27%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
E D P F + VGQ ++ P P+ TW+K+G LP+ +T+ + D +
Sbjct: 16732 EPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTR----INVTDSL 16785
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVT 475
T+ L I D G Y N +G T ++++ PD + +V+ ++T
Sbjct: 16786 DLTT-LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 16844
Query: 476 LEWVPG-FDGGLQSWYRIRYRKVFDDSYKYEDVLPKHA--TNFTVHGLEKNTDYIFSVMA 532
L W P + GG Q I ++ D + DV+ T V L+ T+Y F + A
Sbjct: 16845 LSWNPPLYTGGCQITNYIVQKR--DTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFA 16902
Query: 533 INKIGQS 539
N+ GQS
Sbjct: 16903 ENRYGQS 16909
Score = 56.8 bits (131), Expect = 3e-07
Identities = 50/189 (26%), Positives = 69/189 (36%), Gaps = 13/189 (6%)
Query: 356 PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+ N + VG RL K VP P TW K P + D
Sbjct: 10719 PELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA---------RID 10769
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S L I N A D G Y N G T +VK+ V P L V+ + +
Sbjct: 10770 VTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSC 10829
Query: 475 TLEWVPGFD--GGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMA 532
L W D G + + Y + R V + K ++F H L + Y+F V A
Sbjct: 10830 YLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH-LNEGNQYLFRVAA 10888
Query: 533 INKIGQSKY 541
N+ G+ +
Sbjct: 10889 ENQYGRGPF 10897
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G R + VP P+ W+ +G + + T Y E D+ ++SVL I N D
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSE--IKTDEHYTVE---TDN--FSSVLTIKNCLRRD 11080
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQSW- 489
G Y+ N G T V L V P + + +VT +T+ W P D G
Sbjct: 11081 TGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVI 11140
Query: 490 -YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
Y + + D++ T + L+K +Y+F V A NKIG
Sbjct: 11141 NYIVEKQDTRKDTWGVVS-SGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11188
Score = 56.0 bits (129), Expect = 5e-07
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 18/225 (8%)
Query: 321 IRKAKSENLGNFQ-CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKSAS-NVGQV 374
+ K ++ NF+ C +N G+G +IV+ K P++D K + G
Sbjct: 16403 VEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGS 16462
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
RL K P P W K V+ + A ++TS L+++NV D G
Sbjct: 16463 LRLFVPIKGRPTPEVKWGK------VDGEIRDAAIIDVTS--SFTS-LVLDNVNRYDSGK 16513
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRI 492
Y N G + V + V P V+L VT +T +V++ W P DGG + Y +
Sbjct: 16514 YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIV 16573
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ SY V H ++ + L++ Y F V A N+ G
Sbjct: 16574 EKREATRKSYA-AVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG 16617
Score = 55.6 bits (128), Expect = 7e-07
Identities = 50/170 (29%), Positives = 67/170 (39%), Gaps = 13/170 (7%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY-FAEFHKNDHITYTSVLLINNVATS 430
G+ RL P P+ WSK+G +L + A+F N L+N +T
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN---------LVNKDSTR 15029
Query: 431 -DYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQS 488
D G+Y A N GF+ + V P L VT VT L W P D G
Sbjct: 15030 RDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAK 15089
Query: 489 WYRIRYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
+K + +V + T V L K +YIF VMA+NK G
Sbjct: 15090 IDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYG 15139
Score = 54.8 bits (126), Expect = 1e-06
Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 6/166 (3%)
Query: 376 RLMCKCKSVPAPSFTWSKNG-VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
R+ K P P +W +G K + E + + +SV++I S G
Sbjct: 9332 RIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGK 9391
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRI 492
Y A+N+ G T ++ V P L V+++T + L W +P DGG + Y I
Sbjct: 9392 YSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVI 9451
Query: 493 RYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
R + D + V P +T F V L Y F V A N+ G
Sbjct: 9452 EKRTI--DGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG 9495
Score = 54.4 bits (125), Expect = 2e-06
Identities = 93/400 (23%), Positives = 158/400 (39%), Gaps = 40/400 (10%)
Query: 20 PPSAP-MITGYVPGTTLAAGTVQKLACISTGGNPLAT-LTWFKNDKKIHSTTK-----TT 72
P SAP IT ++ A+ + KL C+ A +TW+K+ KK+ +
Sbjct: 26216 PVSAPPKITQFLKAE--ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSA 26273
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
D +I+ LT +Q +Y CE + T N+ F +A K E V K
Sbjct: 26274 DGTYELKINNLTE--SDQGEYVCEISGEGG------TSKTNLQFMGQAFKSIHEK-VSK- 26323
Query: 133 GIEATLICDSASSNPPATLSWW-RDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
I T D ++ T + P+ + P+ TV ++ +V+A G
Sbjct: 26324 -ISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKF-AVKATGE 26381
Query: 192 PPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV 250
P T WTKDG ITQ Y D+ G L + K D+G+YTC NS G+
Sbjct: 26382 PRP-TAIWTKDGKAITQGGKYKLSEDK---GGFFLEIHKTDTSDSGLYTCTVKNSAGSVS 26437
Query: 251 ANISVSV----HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
++ +++ A S + P + AV+ L +E IK + +
Sbjct: 26438 SSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS-EAKSQEKL 26496
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
++ E + ++K+ + +L + +V+ I ++ + + + +
Sbjct: 26497 ALKEEASKVLISEEVKKSAATSLE--KSIVHEEITKTSQAS----EEVRTHAEIKAFSTQ 26550
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
+ N GQ RL+ K A W NGV+L + +Y
Sbjct: 26551 MSINEGQ--RLVLKANIAGATDVKWVLNGVELTNSEEYRY 26588
Score = 54.0 bits (124), Expect = 2e-06
Identities = 54/188 (28%), Positives = 83/188 (44%), Gaps = 16/188 (8%)
Query: 356 PEMDTSPNFVKSA-SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D S + G+ +++ K P P+ TW K+ L + +Y E
Sbjct: 20772 PEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL--GSDARYSIE----- 20824
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGF-STTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ +S+L I V +D G Y N +G ++TV + V P L V +V+ T
Sbjct: 20825 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGT 20884
Query: 474 VTLEWVPG-FDGGLQSWYRIRYRKVFDDSYKYEDVLPKH---ATNFTVHGLEKNTDYIFS 529
VTL W P DGG I Y D+ K + H +T+F + L + T + F
Sbjct: 20885 VTLLWDPPLIDGGSPI---INYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 20941
Query: 530 VMAINKIG 537
V+A N+IG
Sbjct: 20942 VLAENEIG 20949
Score = 53.6 bits (123), Expect = 3e-06
Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 19/232 (8%)
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS-------NV 371
L++ K F+ N G +V +++ K + SP+ AS +
Sbjct: 9983 LVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRL-VSPDLQLDASVRDRIVVHA 10041
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V R++ P P+ TW+ N LP + + A +S ++I N S
Sbjct: 10042 GGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTA---------ISSSMVIKNCQRSH 10092
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQV-VSLTVTNVTHSTVTLEWV-PGFDGGLQSW 489
G Y A+NE G T+ +DV P V N+T+ + L W P DGG
Sbjct: 10093 QGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPIT 10152
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ ++ D N TV GL + Y F + A N IG +
Sbjct: 10153 NYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPF 10204
Score = 53.2 bits (122), Expect = 4e-06
Identities = 42/154 (27%), Positives = 66/154 (42%), Gaps = 8/154 (5%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P TW+K + L + +++ S + I + SD G+Y A N G
Sbjct: 7221 PEPKITWTKADMILKQDKRITI-------ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7273
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYK 503
+T V+++V P + +T+VT+ + L W P DGG + + R+ D
Sbjct: 7274 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVW 7333
Query: 504 YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
++ TNF L N +YIF V A N G
Sbjct: 7334 HKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 7367
Score = 52.8 bits (121), Expect = 5e-06
Identities = 54/205 (26%), Positives = 89/205 (43%), Gaps = 18/205 (8%)
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
++GI ++V IV+F PE +KS ++ R+ + P P TW K+GV
Sbjct: 21446 SSGIIMTRDENVPPIVEFGPEYFDGL-IIKSGESL----RIKALVQGRPVPRVTWFKDGV 21500
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
++ + + D + TS L + + G Y A+N G + +K+ V
Sbjct: 21501 EIEKRMNMEI------TDVLGSTS-LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21553
Query: 457 APDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQ--SWYRIRYRKVFDDSYK-YEDVLPKHA 512
P +VV + TN+T +TL W + G + Y I R+ ++ ED A
Sbjct: 21554 TPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EA 21611
Query: 513 TNFTVHGLEKNTDYIFSVMAINKIG 537
++T L +Y F V A+NK G
Sbjct: 21612 QSYTAIKLINGNEYQFRVSAVNKFG 21636
Score = 52.4 bits (120), Expect = 6e-06
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ- 487
SD G Y +N G +V + V +P LTV+ VT TL W +P DGG +
Sbjct: 22616 SDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 22675
Query: 488 SWYRIRYRKVFDDSYK-YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ Y + R+ ++ E P ++ V L KN +YIF V A+NK G
Sbjct: 22676 THYIVERRETSRLNWVIVEGECP--TLSYVVTRLIKNNEYIFRVRAVNKYG 22724
Score = 52.0 bits (119), Expect = 8e-06
Identities = 53/204 (25%), Positives = 74/204 (36%), Gaps = 12/204 (5%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G RL K P P TWSK VN + + D T+ L NV D
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPN----VNLRDRIGLDIKSTDFDTF---LRCENVNKYD 13263
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSW- 489
G Y N G T+ + V P V++TV ++ + + W P DGG
Sbjct: 13264 AGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIIN 13323
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
Y ++ R S+ T+F V LE+ Y F V A N+ G P +T+
Sbjct: 13324 YVVQKRDAERKSWS-TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD--PGETRDA 13380
Query: 550 TLTSSEVGELSTVSTEYVETPDIS 573
S G + + V S
Sbjct: 13381 VKASQTPGPVVDLKVRSVSKSSCS 13404
Score = 51.6 bits (118), Expect = 1e-05
Identities = 52/213 (24%), Positives = 82/213 (38%), Gaps = 15/213 (7%)
Query: 332 FQCVVNNGIGSATKQDVMLIVK---FKPEMDTS--PNFVKSASNVGQVGRLMCKCKSVPA 386
F+ N G T ++ ++ + P++D P+ A RL K PA
Sbjct: 13456 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF-RLKIPIKGKPA 13514
Query: 387 PSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFS 446
PS +W K + P+ T T+ E + L++ + SD G Y +N G
Sbjct: 13515 PSVSWKKG--EDPLATDTRVSVE-----SSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13567
Query: 447 TTTVKLDVTSAPD-QVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKVFDDSYKY 504
T+ + V P + VT +TL+W P DGG + I ++ ++
Sbjct: 13568 EGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWV 13627
Query: 505 EDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
T F V L + +Y F V A NK G
Sbjct: 13628 TCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 13660
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/164 (26%), Positives = 69/164 (42%), Gaps = 12/164 (7%)
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
RL K PAP W+++ + S + + + ++L++ NV D G Y
Sbjct: 15382 RLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY---------TLLIVGNVNRFDSGKY 15432
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRIR 493
N G + V + V P L V VT ++VTL W P DGG + Y +
Sbjct: 15433 ILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE 15492
Query: 494 YRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ +Y H T++ V L++ Y F V+A N+ G
Sbjct: 15493 KRESTRKAYS-TVATNCHKTSWKVDQLQEGCSYYFRVLAENEYG 15535
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/70 (35%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 472 STVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFS 529
+T+T+ WV P FDGG + Y + Y+K D +K + T +T+ GL +Y+F
Sbjct: 19601 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWK-TSIQSLRGTEYTISGLTTGAEYVFR 19659
Query: 530 VMAINKIGQS 539
V ++NK+G S
Sbjct: 19660 VKSVNKVGAS 19669
Score = 51.2 bits (117), Expect = 1e-05
Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 11/160 (6%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ TW K+ V P+ +T+ AE +N+ S+L I + D G Y N G
Sbjct: 15678 PTPAVTWHKDNV--PLKQTTRVNAESTENN-----SLLTIKDACREDVGHYVVKLTNSAG 15730
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
+ T+ + V P + + VT ++TL W P +DGG + Y + R +
Sbjct: 15731 EAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTT 15790
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
++ T L+ +Y F + A N+ G+S Y
Sbjct: 15791 WQIVSATVAR-TTIKACRLKTGCEYQFRIAAENRYGKSTY 15829
Score = 51.2 bits (117), Expect = 1e-05
Identities = 58/212 (27%), Positives = 81/212 (38%), Gaps = 19/212 (8%)
Query: 334 CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPS 388
C +N G+G AT + + K PE+D K G R+ K P P
Sbjct: 17499 CALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPE 17558
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTT 448
TWS+ ++ + + YT L I+N +D G Y N G +
Sbjct: 17559 ITWSRE--------EGEFTDKVQIEKGVNYTQ-LSIDNCDRNDAGKYILKLENSSGSKSA 17609
Query: 449 TVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRIRYRKVFDDSYKYED 506
V + V P +L V V + L W P DGG + Y I R+ Y +
Sbjct: 17610 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--STRKAYAN 17667
Query: 507 VLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
V K T+F V L + Y F VMA N+ G
Sbjct: 17668 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFG 17699
Score = 50.8 bits (116), Expect = 2e-05
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 24/307 (7%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS-YSSGNDRI 218
+ +AP F + E + ++ + G P S W K+ LPI+ SS S R
Sbjct: 26633 LSDAPAFISQPRSQNIN-EGQNVLFTCEISGEP-SPEIEWFKNNLPISISSNVSISRSRN 26690
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
+ L + + D+G YT +A N +G A S+ V P ++ S+ VV + D
Sbjct: 26691 VYS---LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV-LPL-VEEPSREVVLRTSGDT 26745
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVT------FEPKNLTSYLIIRKAKSE-NLGN 331
L + + K E S + F + S ++++ E + +
Sbjct: 26746 SLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSS 26805
Query: 332 FQCVVN-NGIGSATKQDVMLIVK-FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
F + N + S+T + + ++ P+++ P+ + + + G+V + C P P
Sbjct: 26806 FMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDI--SIDEGKVLTVACAFTGEPTPEV 26863
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
TWS G K+ ++ E D +T L+I +V D G Y NE G + T
Sbjct: 26864 TWSCGGRKIHSQEQGRFHIE--NTDDLT---TLIIMDVQKQDGGLYTLSLGNEFGSDSAT 26918
Query: 450 VKLDVTS 456
V + + S
Sbjct: 26919 VNIHIRS 26925
Score = 50.4 bits (115), Expect = 3e-05
Identities = 54/220 (24%), Positives = 92/220 (41%), Gaps = 19/220 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFK-----PEMDTSPNFVKSASNV--GQVGRLMCKCKSV 384
F+ N G + ++++L V K PE+D NF V G ++
Sbjct: 19948 FRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK-NFPSHTVYVRAGSNLKVDIPISGK 20006
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL-INNVATSDYGSYECGARNEL 443
P P T S++GV P+ + ++ N IT ++ + + T+D G YE A N
Sbjct: 20007 PLPKVTLSRDGV--PLKATMRF------NTEITAENLTINLKESVTADAGRYEITAANSS 20058
Query: 444 GFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDS 501
G + + + V P + ++++T +VTL+W P +DGG Q I ++ +
Sbjct: 20059 GTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTA 20118
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
E T V L +Y F + A N+ G S +
Sbjct: 20119 VWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDH 20158
Score = 50.0 bits (114), Expect = 3e-05
Identities = 53/217 (24%), Positives = 84/217 (38%), Gaps = 19/217 (8%)
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
V+ + + S V A IK+ S + N + VL G A +KW G +
Sbjct: 26524 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG----ATDVKWVLNGVE 26579
Query: 303 I-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
+ + + + L I++A + G C+ G Q + + K E+ +
Sbjct: 26580 LTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSK---ELSDA 26636
Query: 362 PNFVKSAS----NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
P F+ N GQ C+ P+P W KN LP++ S+ +N
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKN--NLPISISSNVSISRSRN---V 26691
Query: 418 YTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
Y+ L I N + SD G Y A+N G + T L V
Sbjct: 26692 YS--LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 49.2 bits (112), Expect = 6e-05
Identities = 55/242 (22%), Positives = 96/242 (39%), Gaps = 15/242 (6%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT--KTTDKAVS 77
P + P + + T+ G L C G P T+TW++ D +I S+ + T ++
Sbjct: 893 PVTPPTLVSGLKNVTVIEGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGI 951
Query: 78 AEISILTNVTDNQAQYRCEATNSATEI--PLFETVTLNVHFAPEAVKVRAE-PDVLKPGI 134
A + I ++ ++ C A N A + + V ++ F E V + K +
Sbjct: 952 ARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFV 1011
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPS 194
E+ D ++ T G P AP F + +E ++ + GNP
Sbjct: 1012 ESR---DVVMTDTSLTEEQAGPGEPA--APYFITKPVVQKL-VEGGSVVFGCQVGGNPKP 1065
Query: 195 ITYTWTKDGLPITQS-SYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANI 253
Y W K G+P+T Y ++ E ++ ++ DAG YT N G A+
Sbjct: 1066 HVY-WKKSGVPLTTGYRYKVSYNKQTGECKLV-ISMTFADDAGEYTIVVRNKHGETSASA 1123
Query: 254 SV 255
S+
Sbjct: 1124 SL 1125
Score = 49.2 bits (112), Expect = 6e-05
Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 382 KSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARN 441
K P + W K+G L T + T TS L I + D G+YE N
Sbjct: 18922 KGRPQATVNWRKDGQTLKETTRVNV------SSSKTVTS-LSIKEASKEDVGTYELCVSN 18974
Query: 442 ELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFD 499
G T + + V P + + V+ ++T+ W P +DGG Q S Y + ++
Sbjct: 18975 SAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTS 19034
Query: 500 DSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
++ T+ + L ++Y F V A N+ G+S Y
Sbjct: 19035 TTWHIVSQAVAR-TSIKIVRLTTGSEYQFRVCAENRYGKSSY 19075
Score = 48.8 bits (111), Expect = 8e-05
Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 356 PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P F + N G+ RL P P+ W + ++ + E D
Sbjct: 17126 PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR----CEIKNTD 17181
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHST 473
+ ++L++ + D G Y A N G + V + V P + VT VT
Sbjct: 17182 ---FKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEK 17238
Query: 474 VTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATN-FTVHGLEKNTDYIFSV 530
+L W P DGG S Y + R+ + V + TN V L + +Y+F +
Sbjct: 17239 CSLTWSPPLQDGGSDISHYVVEKRET--SRLAWTVVASEVVTNSLKVTKLLEGNEYVFRI 17296
Query: 531 MAINKIG 537
MA+NK G
Sbjct: 17297 MAVNKYG 17303
Score = 48.8 bits (111), Expect = 8e-05
Identities = 49/171 (28%), Positives = 67/171 (39%), Gaps = 10/171 (5%)
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
+ G+ L + P P WSK+G +L A I T+ L++ +
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWSKDGKELEETA-----ARMEIKSTIQKTT-LVVKDCIR 18276
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGF-DGGLQ 487
+D G Y N G + + + V P L VT VT L W P DGG
Sbjct: 18277 TDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGAN 18336
Query: 488 -SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
S Y I R+ S+ A N+ V L +YIF VMA+NK G
Sbjct: 18337 ISHYIIEKRETSRLSWTQVST-EVQALNYKVTKLLPGNEYIFRVMAVNKYG 18386
Score = 48.8 bits (111), Expect = 8e-05
Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 13/157 (8%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
PAP+ W K+ +L N ++ T + +LI + + G YE RN +G
Sbjct: 20403 PAPTIEWYKDDKELQTNALVCV-------ENTTDLASILIKDADRLNSGCYELKLRNAMG 20455
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSY 502
++ T+++ + P + VT +TL W P DGG + + I ++ + S
Sbjct: 20456 SASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKR--ETSR 20513
Query: 503 KYEDVLPKHATN--FTVHGLEKNTDYIFSVMAINKIG 537
++ +H T + K +YIF V A+NK G
Sbjct: 20514 VVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYG 20550
Score = 48.0 bits (109), Expect = 1e-04
Identities = 63/261 (24%), Positives = 107/261 (40%), Gaps = 21/261 (8%)
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA-- 343
G+P L+ H++ KG D + V T Y++ R +++ + F+ N G +
Sbjct: 11632 GSPNLSYHVERRLKGSD-DWERVHKGSIKETHYMVDRCVENQ-IYEFRVQTKNEGGESDW 11689
Query: 344 --TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
T++ V+ KP +D + V + G RL + P P W+K+ +
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVK-AGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11748
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
S + K D +S + SD G Y A N G ++V P V
Sbjct: 11749 RSPRV-----KIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPV 11803
Query: 462 VSLTVTNVTHSTVTLEWVPGFDGG---LQSWY--RIRYRKVFDDSYKYEDVLPKHATNFT 516
+L + +V+ T+ W P D G +Q++ + +++ +Y + P T
Sbjct: 11804 RNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP----GTT 11859
Query: 517 VHGLEKNTDYIFSVMAINKIG 537
V L + +YIF V A NKIG
Sbjct: 11860 VTRLIEGNEYIFRVRAENKIG 11880
Score = 48.0 bits (109), Expect = 1e-04
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIR 493
A NE G + TT + + AP SL + ++T STV+L W P DGG + + Y I
Sbjct: 14446 AENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIE 14505
Query: 494 YRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
++ D + + + V L + +Y F VMA+N G+S R
Sbjct: 14506 AQRKGSDQWTH--ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR 14552
Score = 48.0 bits (109), Expect = 1e-04
Identities = 47/183 (25%), Positives = 71/183 (38%), Gaps = 11/183 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V RL K P P W+K G + +E H + L+I D
Sbjct: 23654 GGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIA-TSETH--------TELVIKEADRGD 23704
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSW 489
G+Y+ N+ G +K+ V +P+ L ++ +V + W P DGG
Sbjct: 23705 SGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23764
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
I R+ + Y T+ V GL++N +Y F V A N+ G SK + T
Sbjct: 23765 GYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23824
Query: 550 TLT 552
T
Sbjct: 23825 PKT 23827
Score = 47.6 bits (108), Expect = 2e-04
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 4/159 (2%)
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
+P P WSKN + T + + T L I D G+Y A N L
Sbjct: 8928 LPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-LSIPKAVREDKGTYTVTASNRL 8986
Query: 444 GFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
G V ++V P +L VT++ + L W P +GG + + Y I R
Sbjct: 8987 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKK 9046
Query: 502 YKYEDVLPKHA-TNFTVHGLEKNTDYIFSVMAINKIGQS 539
++E+V + + L N Y F V A+NK G S
Sbjct: 9047 AEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGIS 9085
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/167 (26%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W K+G P+ +T+ E ++VL I D+G Y A N G
Sbjct: 17842 PRPNISWVKDGE--PLKQTTRVNVE-----ETATSTVLHIKEGNKDDFGKYTVTATNSAG 17894
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVP-GFDGGLQ-SWYRIRYRKVFDDS 501
+T + + V P V + V+ V + W P + GG Q S Y + R +
Sbjct: 17895 TATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTT 17954
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKA 548
+ T + L+ T+Y F + A N+ G+S P D+KA
Sbjct: 17955 WHMVSATVARTT-IKITKLKTGTEYQFRIFAENRYGKS--APLDSKA 17998
Score = 47.2 bits (107), Expect = 2e-04
Identities = 52/183 (28%), Positives = 77/183 (42%), Gaps = 17/183 (9%)
Query: 277 DAVLSCTAIGNPLLAEHIKW--ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN-LGNFQ 333
D V T+I N A+ + W E K D K + +N T L+I K +E+ G +
Sbjct: 4258 DIVHLTTSITN---AKEVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYV 4313
Query: 334 CVVNNGIG-SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWS 392
C N G +AT + ++ + P + ++ A +G + + C+ +S P F W
Sbjct: 4314 CEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVA--LGHLAKFTCEIQSAPNVRFQWF 4371
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K G + + S K K Y S L I D G Y C A NE G + T L
Sbjct: 4372 KAGRE--IYESDKCSIRSSK-----YISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4424
Query: 453 DVT 455
VT
Sbjct: 4425 TVT 4427
Score = 46.8 bits (106), Expect = 3e-04
Identities = 39/115 (33%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Query: 345 KQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL-PVNTS 403
+ D M +++ PE T P + K+A VG+ R P P TW K+G K+ P +
Sbjct: 25182 RTDTMRLLERPPEF-TLPLYNKTAY-VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDND 25239
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
KY E K + L IN+V T D Y ARN+ G + KL VT P
Sbjct: 25240 KKYTFESDKGLY-----QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP 25289
Score = 46.4 bits (105), Expect = 4e-04
Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 11/148 (7%)
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF------STTTVKLDVT 455
T +K +A K+ YT + + + Y + A NE+G S D
Sbjct: 10555 TMSKRWARVTKDPIHPYTKFRVPDLLEGCQY-EFRVSAENEIGIGDPSPPSKPVFAKDPI 10613
Query: 456 SAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHA- 512
+ P V+ + T ++V L W P DGG + Y + Y+KV D+ ++ + P+
Sbjct: 10614 AKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCP 10673
Query: 513 -TNFTVHGLEKNTDYIFSVMAINKIGQS 539
T + V GL Y F V+A+N G+S
Sbjct: 10674 ETKYKVTGLRDGQTYKFRVLAVNAAGES 10701
Score = 46.0 bits (104), Expect = 6e-04
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V+ P L V +VT STVTL W P +DGG + + Y + K + + L
Sbjct: 23134 VSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPT 23193
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATT--LTSSEVGELSTVSTEYVET 569
TV L + Y+F + A N+ G S+ R T T L +LST+ + +
Sbjct: 23194 VLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 23253
Query: 570 PDISKPVIVYVSLTG 584
P +PV + + + G
Sbjct: 23254 P-AGRPVELVIPIAG 23267
Score = 46.0 bits (104), Expect = 6e-04
Identities = 40/172 (23%), Positives = 70/172 (40%), Gaps = 16/172 (9%)
Query: 293 HIKWERKGYKIDP----KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
H+ W + G KI P K TFE L I +++ + V N G + +
Sbjct: 25223 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 25282
Query: 349 MLIVKFKPEMDTS--PNFVKSASNVG-QVGRLMC---KCKSVPAPSFTWSKNGVKLPVNT 402
+ + P D++ P F + +N Q G+ +C + +P P+ W K+G L +
Sbjct: 25283 LTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGP 25342
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ + ++ + Y + L I + D G Y A N G ++ L V
Sbjct: 25343 NIEII-----HEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 45.6 bits (103), Expect = 7e-04
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Query: 172 YNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTK 229
+NT I+ E L I + G P P+I+ W KDG P+ Q++ + + S ++L++ +
Sbjct: 17821 FNTYSIQAGEDLKIEIPVIGRPRPNIS--WVKDGEPLKQTTRVNVEETATS--TVLHIKE 17876
Query: 230 LTRHDAGIYTCEAVNSQGAAVANISVSV 257
+ D G YT A NS G A N+SV V
Sbjct: 17877 GNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 45.6 bits (103), Expect = 7e-04
Identities = 39/161 (24%), Positives = 65/161 (40%), Gaps = 13/161 (8%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W G KL S + E H T + L I D G Y +N G
Sbjct: 23269 PPPAASWFFAGSKL--RESERVTVETH-----TKVAKLTIRETTIRDTGEYTLELKNVTG 23321
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
++ T+K+ + P + + + +++T+ W P DGG S Y + R
Sbjct: 23322 TTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPG 23381
Query: 502 Y-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ + + + FT L + +Y+F V A N+ G Y
Sbjct: 23382 WLPVSESVTRSTFKFT--RLTEGNEYVFRVAATNRFGIGSY 23420
Score = 45.2 bits (102), Expect = 0.001
Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLN 226
D +++ + IE E L I V P T +W KDG + S + ND I + L
Sbjct: 7893 DLETHDIIVIEGEKLSIPVPFRAVPVP-TVSWHKDGKEVKASDRLTMKNDHISAH---LE 7948
Query: 227 MTKLTRHDAGIYTCEAVNSQGAAVANISVSV 257
+ K R DAGIYT N G+A A+I+V V
Sbjct: 7949 VPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 17/125 (13%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVH-------------YPAGIKSVSQNVVANPNEDAVL 280
DA +YTCEA N G A + S+SV YP I + Q+ V + + A
Sbjct: 3259 DAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARF 3318
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSY-LIIRKAKSENLGNFQCVVNNG 339
C G L + W K KI P + +Y L I +A E+ G + V +N
Sbjct: 3319 QCRVSGTDL---KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNA 3375
Query: 340 IGSAT 344
+G +
Sbjct: 3376 VGQVS 3380
Score = 44.8 bits (101), Expect = 0.001
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 6/148 (4%)
Query: 395 GVKLPVNTSTKYFAEFHKN----DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
G +P TK E K+ D++ S L+I + D+G Y A N G
Sbjct: 8633 GRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAA 8692
Query: 451 KLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKVFDDSYKYEDVLP 509
+++V P V+ L L W P DGG + I RK + + +
Sbjct: 8693 RVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERK-DAKMHTWRQPIE 8751
Query: 510 KHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ + GL + +Y F V+A NK G
Sbjct: 8752 TERSKCDITGLLEGQEYKFRVIAKNKFG 8779
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRI 492
+ CG E+G + +D P LT T T ST+TL+W P +GG Y I
Sbjct: 8778 FGCGPPVEIG---PILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 8834
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
R+ ++ + T+F V L+++ Y F V A+N+IG+S+
Sbjct: 8835 EKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 8882
Score = 44.8 bits (101), Expect = 0.001
Identities = 41/170 (24%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G+V ++ P P +W+K+G+++ T+ + ++H ++L + + D
Sbjct: 19307 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEIIST---DNH----TLLTVKDCIRRD 19359
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWV-PGFDGGLQ-S 488
G Y +N G + V V P L + +T +L W P DGG
Sbjct: 19360 TGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 19419
Query: 489 WYRIRYRKVFDDSYKY-EDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+Y + R+ ++ E L T+ V L K +YIF V +NK G
Sbjct: 19420 YYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYG 19467
Score = 44.4 bits (100), Expect = 0.002
Identities = 39/156 (25%), Positives = 60/156 (38%), Gaps = 12/156 (7%)
Query: 306 KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD-TSPNF 364
+ + E K +S + + + + Q N + + KF E + T P F
Sbjct: 3400 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIF 3459
Query: 365 VKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
+K SN +G V L +P P W NGV L + K+ F +DH
Sbjct: 3460 IKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFV--FDGDDH----- 3512
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L+I D G Y C A N+ G + + L + S
Sbjct: 3513 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3548
Score = 44.4 bits (100), Expect = 0.002
Identities = 85/372 (22%), Positives = 144/372 (38%), Gaps = 38/372 (10%)
Query: 190 GNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGA 248
G P P + +T KD +T+S + R ++ S ++TK R D G Y A N+ G+
Sbjct: 11730 GKPFPEVAWTKDKDATDLTRSPRVKIDTR--ADSSKFSLTKAKRSDGGKYVVTATNTAGS 11787
Query: 249 AVANISVSV-HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGY---KID 304
VA +V+V P ++++ + + + D CT +P + E + Y K +
Sbjct: 11788 FVAYATVNVLDKPGPVRNLK---IVDVSSD---RCTVCWDP-PEDDGGCEIQNYILEKCE 11840
Query: 305 PKSV---TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA-TKQDVMLIVKFKPEMDT 360
K + T+ LT + + N F+ N IG+ + +I K K +
Sbjct: 11841 TKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPG 11900
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF-HKNDHITYT 419
P+ V +V + P P + K+ + K+ + N
Sbjct: 11901 RPD----PPEVTKVSKEEMTVVWNP-PEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE 11955
Query: 420 SVLLINNVATSDYGSYECGARNELGF------STTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ + N+ + A NE+G S V D P + V + T +
Sbjct: 11956 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHS 12015
Query: 474 VTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHAT------NFTVHGLEKNTD 525
+TL W P +DGG Y + R D+ E +A FTV L++N +
Sbjct: 12016 ITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 12075
Query: 526 YIFSVMAINKIG 537
Y F V A N++G
Sbjct: 12076 YEFRVCAQNQVG 12087
Score = 44.4 bits (100), Expect = 0.002
Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 16/161 (9%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P +WSK G + + T+ + +S+L I D G Y A N G
Sbjct: 13910 PLPKSSWSKAGKDIRPSDITQITST-------PTSSMLTIKYATRKDAGEYTITATNPFG 13962
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSY 502
VK+ V P + ++NV+ TL W P DGG Y + R+ +
Sbjct: 13963 TKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLW 14022
Query: 503 KY--EDVLP-KHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
ED+ +H + G +YIF V A+N G+ +
Sbjct: 14023 TVVSEDIQSCRHVATKLIQG----NEYIFRVSAVNHYGKGE 14059
Score = 44.4 bits (100), Expect = 0.002
Identities = 60/227 (26%), Positives = 88/227 (38%), Gaps = 18/227 (7%)
Query: 320 IIRKAKSENLGNFQCVVNNGIG-SATKQDVMLIVKFK---PEMDTSPNFVKSA-SNVGQV 374
++R FQ + N G SA ++ +IVK + PE+D + K + G
Sbjct: 14526 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDN 14585
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL-INNVATSDYG 433
++ P P+ TW K G ++ T F T TS +L IN SD G
Sbjct: 14586 IKVEIPVLGRPKPTVTWKK-GDQILKQTQRVNF-------ETTATSTILNINECVRSDSG 14637
Query: 434 SYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWY 490
Y ARN +G + + V P + V+ VT W P DGG+ S Y
Sbjct: 14638 PYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNY 14697
Query: 491 RIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ R+ D + E T + L +Y F V A N+ G
Sbjct: 14698 VVEMRQT-DSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14743
Score = 44.4 bits (100), Expect = 0.002
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I + + + DD T+ L + V G PP + TW+K G+ + + +
Sbjct: 22944 IEIPDLELADDLKKTVTIRA-GASLRLMVSVSGRPPPVI-TWSKQGIDLASRAIIDTTES 23001
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG 262
S+L + K+ R+DAG YT EA N G A + V V+ G
Sbjct: 23002 Y----SLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG 23042
Score = 44.0 bits (99), Expect = 0.002
Identities = 53/215 (24%), Positives = 85/215 (39%), Gaps = 20/215 (9%)
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS---VTFEPKNLTSYLIIRKA 324
Q+VV A G P+ + W R G I + V + + L I
Sbjct: 13 QSVVVLEGSTATFEAHISGFPV--PEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAV 70
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCK 380
N G + NG G AT +L+ K E PNFV+ ++ G RL +
Sbjct: 71 TKANSGRYSLKATNGSGQATSTAELLV---KAET-APPNFVQRLQSMTVRQGSQVRLQVR 126
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
+P P + ++G ++ S+ F + D Y+ LLI D G+Y A
Sbjct: 127 VTGIPTPVVKFYRDGAEIQ---SSLDFQISQEGD--LYS--LLIAEAYPEDSGTYSVNAT 179
Query: 441 NELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVT 475
N +G +T+T +L V + T T V+ + ++
Sbjct: 180 NSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQIS 214
Score = 43.6 bits (98), Expect = 0.003
Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHA--TNFTVHGLE 521
V + T S+V+L W P +DGG Y + ++ D++ + LP++ T F V GL
Sbjct: 13100 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCN-LPQNLQKTRFEVTGLM 13158
Query: 522 KNTDYIFSVMAINKIGQS 539
++T Y F V A+NKIG S
Sbjct: 13159 EDTQYQFRVYAVNKIGYS 13176
Score = 43.6 bits (98), Expect = 0.003
Identities = 40/155 (25%), Positives = 63/155 (40%), Gaps = 12/155 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ WSK L T+ + D + L I N +D G Y +N L
Sbjct: 19717 PVPNVLWSKPDTDL----RTRAYV-----DTTDSRTSLTIENANRNDSGKYTLTIQNVLS 19767
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSY 502
++ T+ + V P ++TV +VT + L W VP DGG Y I R+ ++
Sbjct: 19768 AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAW 19827
Query: 503 KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ ++ V L++ Y F V N+ G
Sbjct: 19828 -VSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFG 19861
Score = 43.2 bits (97), Expect = 0.004
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Query: 456 SAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHAT 513
+ P++ L V VT +TVTL W P +DGG + Y + R + + + +
Sbjct: 10218 TVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSR 10277
Query: 514 NFTVHGLEKNTDYIFSVMAINKIGQSK 540
+TV GL++ Y + V A+N +GQ K
Sbjct: 10278 KYTVKGLKEGDTYEYRVSAVNIVGQGK 10304
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 12/156 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W K+G L K + +N L + +V D G Y A N G
Sbjct: 12826 PMPTVSWKKDGTLLKPAEGIKMAMQ--RN-----LCTLELFSVNRKDSGDYTITAENSSG 12878
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSY 502
+ T+KL V P S+ + + L W P DGG + + Y + R+ ++
Sbjct: 12879 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 12938
Query: 503 -KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ +P T+ +V L + +Y F + A NK G
Sbjct: 12939 AQVSATVP--ITSCSVEKLIEGHEYQFRICAENKYG 12972
Score = 42.7 bits (96), Expect = 0.005
Identities = 31/80 (38%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 464 LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLE 521
L V N+T +T L+W VP DGG + Y + R V ++ D K T TV L
Sbjct: 7593 LEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLT 7651
Query: 522 KNTDYIFSVMAINKIGQSKY 541
+ + Y+F V A N IGQS Y
Sbjct: 7652 EGSLYVFRVAAENAIGQSDY 7671
Score = 42.7 bits (96), Expect = 0.005
Identities = 49/226 (21%), Positives = 88/226 (38%), Gaps = 11/226 (4%)
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV--GQVGR 376
L++ K F+ N +G + ++ + + K ++ + + G+ R
Sbjct: 12361 LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLR 12420
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
+ P P+ W K ++ ++ + A HK D +S+L+I +V D G Y
Sbjct: 12421 IEAHVYGKPHPTCKWKKGEDEV---VTSSHLA-VHKADS---SSILIIKDVTRKDSGYYS 12473
Query: 437 CGARNELGFSTTTVKLDVTSAP-DQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRY 494
A N G T +K+ V AP ++++ +L W +P DGG I
Sbjct: 12474 LTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVE 12533
Query: 495 RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + T+ V L +YIF V A N+ G S+
Sbjct: 12534 KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12579
Score = 42.3 bits (95), Expect = 0.007
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 469 VTHSTVTLEWV-PGFDGG-LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDY 526
V + +TL+W P +DGG + + Y + R + D + T FTV GL ++ Y
Sbjct: 17035 VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRY 17094
Query: 527 IFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVIVYVSLTGAV 586
F V+A N G +P D+ EV EL +S + P ++V T +
Sbjct: 17095 EFRVIAKNAAGAIS-KPSDSTGPITAKDEV-ELPRISMD----PKFRDTIVVNAGETFRL 17148
Query: 587 LVLINVALIACFVWKRRLRRIKEQA 611
++ + W R + I+E A
Sbjct: 17149 EADVHGKPLPTIEWLRGDKEIEESA 17173
Score = 42.3 bits (95), Expect = 0.007
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIR 493
A NE G + TT + V+ P +T+ +VT +T T++W P DGG + + Y +
Sbjct: 18777 ASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVE 18836
Query: 494 YRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
+ S K+ T+ GL +Y+F V A+N+ G+S R
Sbjct: 18837 MQT--KGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPR 18883
Score = 42.3 bits (95), Expect = 0.007
Identities = 54/192 (28%), Positives = 77/192 (40%), Gaps = 18/192 (9%)
Query: 356 PEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D S + +G L K P PS +W K+G LP+ S F F K +
Sbjct: 21064 PEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDG--LPLKESE--FVRFSKTE 21119
Query: 415 HITYTSVLLINNVATSDYGSYECGARN---ELGFSTTTVKLDVTSAPDQVVSLTVTNVTH 471
+ L I N G Y N + T + L S P + +
Sbjct: 21120 N---KITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRF--DEIKA 21174
Query: 472 STVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA-TNFTVHGLEKNTDYIF 528
+V L W VP +GG + + Y I R+ ++K V A T F V L K+ +Y F
Sbjct: 21175 DSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKM--VCSSVARTTFKVPNLVKDAEYQF 21232
Query: 529 SVMAINKIGQSK 540
V A N+ G S+
Sbjct: 21233 RVRAENRYGVSQ 21244
Score = 41.9 bits (94), Expect = 0.009
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYKYEDVLPK 510
D S PD L VT +T ++ TL W+P DGG + Y YR+ + ++ +
Sbjct: 12297 DPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV 12356
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ V GL++ Y F V A N +G S
Sbjct: 12357 KDLSLVVTGLKEGKKYKFRVAARNAVGVS 12385
Score = 41.5 bits (93), Expect = 0.012
Identities = 44/156 (28%), Positives = 63/156 (40%), Gaps = 11/156 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ W K +L NT+ E D T SV + D G+Y A+N G
Sbjct: 16074 PIPTIQWIKGDQELS-NTAR---LEIKSTDFATSLSV---KDAVRVDSGNYILKAKNVAG 16126
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGF-DGGLQSW-YRIRYRKVFDDS 501
+ TV + V P + ++ VT TL W P DGG Y + R+
Sbjct: 16127 ERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLV 16186
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ D + + LE N +Y F +MA+NK G
Sbjct: 16187 WTVVDANVQTLSCKVTKLLEGN-EYTFRIMAVNKYG 16221
Score = 41.1 bits (92), Expect = 0.016
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 10/125 (8%)
Query: 424 INNVATSDYGSYECGARNELGF-----STTTVKL-DVTSAPDQVVSLTVTNVTHSTVTLE 477
+ +V S+ A+N +G +T VK+ D P V+LT ++ T S+V L+
Sbjct: 6755 VTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLK 6814
Query: 478 WVPGF-DGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAIN 534
W P DGG + + R + D+ + L T + V GLEK Y++ V A N
Sbjct: 6815 WEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELT-YKVTGLEKGNKYLYRVSAEN 6873
Query: 535 KIGQS 539
K G S
Sbjct: 6874 KAGVS 6878
Score = 41.1 bits (92), Expect = 0.016
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 5/108 (4%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRY 494
A NE G + T + V P +TV +VT ++V+L W P DGG + I
Sbjct: 16612 AENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVE 16671
Query: 495 RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
+ S K+ + + + L + +Y+F V+A+N+ G+S R
Sbjct: 16672 MQA-KHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 16718
Score = 40.7 bits (91), Expect = 0.021
Identities = 39/129 (30%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGF-----STTTVKLDVTSAPDQVVSLTVTNVTH 471
+YT++ LIN ++Y + A N+ G S V + PD +N+T
Sbjct: 21613 SYTAIKLING---NEY-QFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITG 21668
Query: 472 STVTLEWV-PGFDGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIF 528
+++TL W P DGG +Q + R K K P T F V GL + +Y F
Sbjct: 21669 NSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEF 21728
Query: 529 SVMAINKIG 537
VMA N G
Sbjct: 21729 HVMAENAAG 21737
Score = 40.3 bits (90), Expect = 0.028
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 9/90 (10%)
Query: 364 FVKSASNVGQVGRLMCKCKS--VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
F+K+ ++ ++ +L C +S + A TW K+G KL N +F +FH + TY
Sbjct: 26226 FLKAEASK-EIAKLTCVVESSVLRAKEVTWYKDGKKLKENG---HF-QFHYSADGTYE-- 26278
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVK 451
L INN+ SD G Y C E G S T ++
Sbjct: 26279 LKINNLTESDQGEYVCEISGEGGTSKTNLQ 26308
Score = 39.9 bits (89), Expect = 0.037
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L+I+ SD G Y N + + + ++V + P L ++T +V L W P
Sbjct: 6955 LVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPP 7014
Query: 482 FD--GGLQSWYRIRYRKVFDDSY-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
D G + Y + R+V ++ K D + FTV L + +Y+F V A NK G
Sbjct: 7015 DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTD--LEFTVPDLVQGKEYLFKVCARNKCG 7071
Score = 39.9 bits (89), Expect = 0.037
Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 180 EPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
E L I G P P +T W KDG+ I + D + S + L + TR G+Y
Sbjct: 21477 ESLRIKALVQGRPVPRVT--WFKDGVEIEKRMNMEITDVLGS--TSLFVRDATRDHRGVY 21532
Query: 239 TCEAVNSQGAAVANISVSVHYPAG 262
T EA N+ G+A A I V V G
Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTPG 21556
Score = 39.5 bits (88), Expect = 0.048
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 172 YNTVGI-ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTK 229
+NT + E L + V G P P++T W KD +P+ Q+ + N S+L +
Sbjct: 15657 FNTFTVLAGEDLKVDVPFIGRPTPAVT--WHKDNVPLKQT--TRVNAESTENNSLLTIKD 15712
Query: 230 LTRHDAGIYTCEAVNSQGAAVANISVSV 257
R D G Y + NS G A+ ++V V
Sbjct: 15713 ACREDVGHYVVKLTNSAGEAIETLNVIV 15740
Score = 39.5 bits (88), Expect = 0.048
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
+ L I V G P T TWTKDGLP+ Q++ + D + + + L++ + + D G Y
Sbjct: 16748 QDLKIEVPISGRPKP-TITWTKDGLPLKQTTRINVTDSL--DLTTLSIKETHKDDGGQYG 16804
Query: 240 CEAVNSQGAAVANISV 255
N G A+I +
Sbjct: 16805 ITVANVVGQKTASIEI 16820
Score = 39.1 bits (87), Expect = 0.064
Identities = 82/387 (21%), Positives = 146/387 (37%), Gaps = 30/387 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
E + G PP T W+KDG + ++ +I + L TR D+G YT
Sbjct: 14980 EAFRLEADVSGRPPP-TMEWSKDGKELEGTAKLE--IKIADFSTNLVNKDSTRRDSGAYT 15036
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAI---GNPLLAEHIKW 296
A N G A +V V G V +E VLS G + +I
Sbjct: 15037 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 15096
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAK-SENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+R+ ++ +V E + +T + + K +E + V G+G + + +L V
Sbjct: 15097 KRETSRLAWTNVASEVQ-VTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVN-- 15153
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P P + + + ++C P + V K + K +
Sbjct: 15154 PYGPPDPPKNPEVTTITKDSMVVCWGH----PDSDGGSEIINYIVERRDKAGQRWIKCNK 15209
Query: 416 ITYTSVLL-INNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV------SLTVTN 468
T T + ++ + + A N G S + A D V + V +
Sbjct: 15210 KTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLD 15269
Query: 469 VTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK---HATNFTVHGLEKN 523
+ S++++ W P +DGG + + Y + +D ++ V P AT++T+ GL +N
Sbjct: 15270 TSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI--VTPPAGLKATSYTITGLTEN 15327
Query: 524 TDYIFSVMAINK--IGQSKYRPDDTKA 548
+Y + A+N +G+ P KA
Sbjct: 15328 QEYKIRIYAMNSEGLGEPALVPGTPKA 15354
Score = 38.7 bits (86), Expect = 0.084
Identities = 46/196 (23%), Positives = 79/196 (40%), Gaps = 14/196 (7%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISE 221
AP F + V +E G P P ++ W +DG I+ S+ G S+
Sbjct: 5 APTFTQPLQ-SVVVLEGSTATFEAHISGFPVPEVS--WFRDGQVISTSTL-PGVQISFSD 60
Query: 222 G-SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH---YPAGIKSVSQNVVANPNED 277
G + L + +T+ ++G Y+ +A N G A + + V P Q++
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQ 120
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFE--PKNLTSYLIIRKAKSENLGNFQCV 335
L G P +K+ R G +I S+ F+ + L+I +A E+ G +
Sbjct: 121 VRLQVRVTGIP--TPVVKFYRDGAEIQ-SSLDFQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 336 VNNGIGSATKQDVMLI 351
N +G AT +L+
Sbjct: 178 ATNSVGRATSTAELLV 193
Score = 38.7 bits (86), Expect = 0.084
Identities = 59/216 (27%), Positives = 81/216 (37%), Gaps = 32/216 (14%)
Query: 260 PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSY 318
P IK VS N + + A LS T IG P I+W G + P + F
Sbjct: 3457 PIFIKEVS-NADISMGDVATLSVTVIGIP--KPKIQWFFNGVLLTPSADYKFVFDGDDHS 3513
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI-VKFKPEMDTS---------------- 361
LII K E+ G + C+ +N G + I K + DT
Sbjct: 3514 LIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 3573
Query: 362 -PNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
P+F+K + G PAP+ TW K +L TS Y + N
Sbjct: 3574 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLC--TSVYYTIIHNPNGSG 3631
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
T+ ++N+ D G Y C A N LG ST +L
Sbjct: 3632 TF----IVNDPQREDSGLYICKAENMLGESTCAAEL 3663
Score = 38.7 bits (86), Expect = 0.084
Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 11/131 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAP 387
F+ N G + + + +K K +P K +V G+ +L C+ P P
Sbjct: 24006 FRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLP 24065
Query: 388 SFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFST 447
W + G +L S KY +D T+T L + D G Y C A NE+G
Sbjct: 24066 DIKWYRFGKELI--QSRKYKMS---SDGRTHT--LTVMTEEQEDEGVYTCIATNEVGEVE 24118
Query: 448 TTVKLDVTSAP 458
T+ KL + + P
Sbjct: 24119 TSSKLLLQATP 24129
Score = 37.9 bits (84), Expect = 0.15
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSS-GNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P++ + W K G I +S S + + IS +L T++ D G YTC+A N G+
Sbjct: 4364 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR-TQVV--DCGEYTCKASNEYGSVSC 4420
Query: 252 NISVSVHYPAGIKSVSQNV---VANPNEDAVL 280
+++V P G K V + + P E+ VL
Sbjct: 4421 TATLTVTVPGGEKKVRKLLPERKPEPKEEVVL 4452
Score = 37.9 bits (84), Expect = 0.15
Identities = 58/269 (21%), Positives = 101/269 (37%), Gaps = 19/269 (7%)
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L T G P+ + W++ G + P + + + L + ++ G++ N
Sbjct: 12818 LDATVFGKPMPT--VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 12875
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
GS + + L V KP S K S+ R M + + N +
Sbjct: 12876 SSGSKSAT-IKLKVLDKPGPPASVKINKMYSD-----RAMLSWEPPLEDGGSEITNYIVD 12929
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG-----FSTTTVKLD 453
TS +A+ IT SV + + +Y C A N+ G F+ + +
Sbjct: 12930 KRETSRPNWAQVSATVPITSCSVEKL--IEGHEYQFRIC-AENKYGVGDPVFTEPAIAKN 12986
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ--SWYRIRYRKVFDDSYKYEDVLPKH 511
P + ++N+T +T+ W P D G + Y + R+ ++ + P
Sbjct: 12987 PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPII 13046
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
GL++ T+Y F V AINK G K
Sbjct: 13047 ERTLKATGLQEGTEYEFRVTAINKAGPGK 13075
Score = 37.9 bits (84), Expect = 0.15
Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 10/128 (7%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKY-EDVLPKHATNFTVHGLEK 522
VT+ + S+V+L W P +DGG Y + ++ D + FTV L++
Sbjct: 18514 VTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKE 18573
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVIVYVSL 582
NT+Y F + AIN G + TL S V + E D+ K V++ S
Sbjct: 18574 NTEYNFRICAINSEGVG-------EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18626
Query: 583 TGAVLVLI 590
T + V I
Sbjct: 18627 TLRLFVTI 18634
Score = 37.9 bits (84), Expect = 0.15
Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 458 PDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHATNF 515
P VV +T T+ T TV+LEW P FDGG++ Y I K + + T +
Sbjct: 21759 PPTVVKVTDTSKT--TVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRY 21816
Query: 516 TVHGLEKNTDYIFSVMAINKIGQ 538
TV L+ +Y F V AIN G+
Sbjct: 21817 TVTDLQAGEEYKFRVSAINGAGK 21839
Score = 37.9 bits (84), Expect = 0.15
Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 41/379 (10%)
Query: 184 ISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT--RHDAGIYTC 240
+S + G P P I W + G + QS ++ S+G +T +T + D G+YTC
Sbjct: 24055 LSCQIVGRPLPDIK--WYRFGKELIQSR----KYKMSSDGRTHTLTVMTEEQEDEGVYTC 24108
Query: 241 EAVNSQGAAVAN----ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
A N G + + + + G + + L IG P+ A + W
Sbjct: 24109 IATNEVGEVETSSKLLLQATPQFHPGY-PLKEKYYGAVGSTLRLHVMYIGRPVPA--MTW 24165
Query: 297 ERKGYKI--DPKSVTFEPKNLTSYLIIRKA-KSENLGNFQCVVNNGIGSATKQDVMLIVK 353
G K+ + +++T E ++L+++ + + G ++ ++N G+ D +L V+
Sbjct: 24166 FH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTV---DAILDVE 24221
Query: 354 F--KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
KP+ T P +++ V K +W N V K AE+
Sbjct: 24222 IQDKPDKPTGPIVIEALLKNSAV----ISWKPPADDGGSWITNYV--VEKCEAKEGAEWQ 24275
Query: 412 -KNDHITYTSVLLINNVATSDYGSYECGARNELGF------STTTVKLDVTSAPDQVVSL 464
+ I+ T+ ++N + Y + A+N G S+ + P
Sbjct: 24276 LVSSAISVTTCRIVNLTENAGY-YFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKP 24334
Query: 465 TVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
T+T VT + + W P DGG + Y + R+ + + T F+V L +
Sbjct: 24335 TITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIE 24394
Query: 523 NTDYIFSVMAINKIGQSKY 541
+Y F V N G+S++
Sbjct: 24395 GLEYEFRVKCENLGGESEW 24413
Score = 37.5 bits (83), Expect = 0.19
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 5/126 (3%)
Query: 446 STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYK 503
S + LD P + V L N+T TVTL+W P + GG + + Y + R + + +
Sbjct: 14851 SEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWL 14907
Query: 504 YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVS 563
+ FTV GL ++ Y F V+A N G + + A T V
Sbjct: 14908 KANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVD 14967
Query: 564 TEYVET 569
++ +T
Sbjct: 14968 VKFKDT 14973
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 12/125 (9%)
Query: 51 NPLATLTWFKNDKKIH------STTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEI 104
+P +TW+K+ +KI T +DK + +++I + TD+ A+Y A N E
Sbjct: 25219 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY-QLTINSVTTDDDAEYTVVARNKYGED 25277
Query: 105 PLFETVTLNVHFAPEAVKVRAEPDVLKPGIEAT---LICDS--ASSNPPATLSWWRDGIP 159
+T+ +H P +R L E +C S PP TL W +DG P
Sbjct: 25278 SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQP 25337
Query: 160 VQNAP 164
+ P
Sbjct: 25338 LSLGP 25342
Score = 37.1 bits (82), Expect = 0.26
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL-----TVTNVTHSTVTLEWVPGF-D 483
SDY + A N G ++ D +A D + VT+ T S+ LEW P D
Sbjct: 9892 SDY-QFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKD 9950
Query: 484 GGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
GG + + Y + Y++ + ++ T V GL++ Y F V A+N G
Sbjct: 9951 GGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVSAVNIAG 10005
Score = 37.1 bits (82), Expect = 0.26
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Query: 466 VTNVTHSTVTLEWV-PGFDGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
V + T +++L W P +DGG + + K D Y+ T FTV L+
Sbjct: 22853 VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKM 22912
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGEL 559
Y F V A+N G S+Y + + E+ +L
Sbjct: 22913 GQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDL 22949
Score = 37.1 bits (82), Expect = 0.26
Identities = 55/254 (21%), Positives = 103/254 (40%), Gaps = 18/254 (7%)
Query: 296 WERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W G K+ + + VT E + L IR+ + G + + N G+ T + + +I+
Sbjct: 23275 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGT-TSETIKVIILD 23333
Query: 355 KPEMDTSPNFVKS--ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP--VNTSTKYFAEF 410
KP T P + A+++ P + + P + S
Sbjct: 23334 KPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST 23393
Query: 411 HKNDHITYTSVLLINNVATSDYG--SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
K +T + + AT+ +G SY ++E+ +++++ P +L + +
Sbjct: 23394 FKFTRLTEGNEYVFRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPETLQIFD 23445
Query: 469 VTHSTVTLEWVP-GFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDY 526
V+ +TL W P DGG Q + Y + ++V D + + +P T + GL + +Y
Sbjct: 23446 VSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEY 23505
Query: 527 IFSVMAINKIGQSK 540
V AIN G K
Sbjct: 23506 EHRVTAINARGSGK 23519
Score = 36.7 bits (81), Expect = 0.34
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 6/107 (5%)
Query: 438 GARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRIRYR 495
G + + D PD V + V N T +T+ W P +DGG + Y I
Sbjct: 8063 GGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKI 8122
Query: 496 KVFDDSYK--YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
++ +K E ++P +T GLE+ +Y F V A N G S+
Sbjct: 8123 AKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGISE 8167
Score = 36.7 bits (81), Expect = 0.34
Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V APD+ TV++VT +++T+ W P +DGG + Y + + +K + P
Sbjct: 9819 VPGAPDKP---TVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIK 9875
Query: 512 A----TNFTVHGLEKNTDYIFSVMAINKIG 537
A ++ V GL + +DY F V AIN G
Sbjct: 9876 AMTLGVSYKVTGLIEGSDYQFRVYAINAAG 9905
Score = 36.3 bits (80), Expect = 0.45
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 19/122 (15%)
Query: 137 TLICDSASSNPPATLS-WWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSI 195
T+IC P L +DG+ ++ DT N + I +PL P S
Sbjct: 13869 TIICKDEYEAPTIVLDPTIKDGLTIKAG----DTIVLNAISILGKPL---------PKS- 13914
Query: 196 TYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
+W+K G I S + S SML + TR DAG YT A N G V ++ V
Sbjct: 13915 --SWSKAGKDIRPSDITQITSTPTS--SMLTIKYATRKDAGEYTITATNPFGTKVEHVKV 13970
Query: 256 SV 257
+V
Sbjct: 13971 TV 13972
Score = 35.9 bits (79), Expect = 0.60
Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSA 78
+AP+I + +A G + K C P WFK ++I+ + K + K +S+
Sbjct: 4335 AAPVIKRKIEPLEVALGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4393
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+ T V D +Y C+A+N + T+T+ V
Sbjct: 4394 LEILRTQVVDC-GEYTCKASNEYGSVSCTATLTVTV 4428
Score = 35.9 bits (79), Expect = 0.60
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 465 TVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSY-KYEDVLPKHATNFTVHGLE 521
TV +V ++V L W P DGG + Y I K D + + + +P T + GL
Sbjct: 7494 TVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVP--TTQHLLPGLM 7551
Query: 522 KNTDYIFSVMAINKIGQSK 540
+ +Y F V A+NK G+S+
Sbjct: 7552 EGQEYSFRVRAVNKAGESE 7570
Score = 35.9 bits (79), Expect = 0.60
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 32 GTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHST--TKTTDKAVSAEISILTNVTDN 89
G T+ AG L IS G PL +W K K I + T+ T S+ ++I +
Sbjct: 13890 GLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKD 13949
Query: 90 QAQYRCEATNS-ATEIPLFETVTLNVHFAPEAVKV 123
+Y ATN T++ + L+V P V++
Sbjct: 13950 AGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEI 13984
Score = 35.9 bits (79), Expect = 0.60
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 11/100 (11%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT----KTTDK 74
DPP M Y + AG K+ G P+ T+ W K D+++ +T K+TD
Sbjct: 16042 DPPRISMDPKYKDTIVVHAGESFKVDA-DIYGKPIPTIQWIKGDQELSNTARLEIKSTDF 16100
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
A S +S+ V + Y +A N A E +VT+NV
Sbjct: 16101 ATS--LSVKDAVRVDSGNYILKAKNVAGE----RSVTVNV 16134
Score = 35.9 bits (79), Expect = 0.60
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK 510
D P + + + T S++TL W P +DGG + Y + R+ ++ + +
Sbjct: 20665 DPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGE 20724
Query: 511 -HATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
T + V L+ +Y F V A+N GQ +
Sbjct: 20725 VRTTEYVVSNLKPGVNYYFRVSAVNCAGQGE 20755
Score = 35.9 bits (79), Expect = 0.60
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 3/113 (2%)
Query: 16 SPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKI--HSTTKTTD 73
+P S P+I + TT+++ +V K A +T G P T W K+ K I K ++
Sbjct: 26347 APEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT-GEPRPTAIWTKDGKAITQGGKYKLSE 26405
Query: 74 KAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAE 126
+ I T + Y C NSA + +T+ EA KV +
Sbjct: 26406 DKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26458
Score = 35.5 bits (78), Expect = 0.79
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 8/137 (5%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTK---TTDKAVSAEI 80
PMI + T G + L T + W+ +K + S K D+ +
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKEV---NWYFENKLVPSDEKFKCLQDQNTYTLV 4299
Query: 81 SILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLIC 140
N D+Q +Y CEA N + + +T+ AP +K + EP + G A C
Sbjct: 4300 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP-VIKRKIEPLEVALGHLAKFTC 4358
Query: 141 DSASSNPPATLSWWRDG 157
+ S+ P W++ G
Sbjct: 4359 EIQSA-PNVRFQWFKAG 4374
Score = 35.5 bits (78), Expect = 0.79
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
VTN+T +V+L+W P +DGG + + Y + R++ D + + T F V L ++
Sbjct: 19196 VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 19255
Query: 524 TDYIFSVMAINKIGQSKYRPDDTKATTLTSSEV 556
Y F V A N S P ++ + +V
Sbjct: 19256 QRYEFRVFARN-AADSVSEPSESTGPIIVKDDV 19287
Score = 35.1 bits (77), Expect = 1.0
Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 23 APMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTK--TTDKAVSAEI 80
AP I + T G +L+C G PL + W++ K++ + K + + +
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSC-QIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTL 24093
Query: 81 SILTNVTDNQAQYRCEATNSATEI 104
+++T +++ Y C ATN E+
Sbjct: 24094 TVMTEEQEDEGVYTCIATNEVGEV 24117
Score = 34.7 bits (76), Expect = 1.4
Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 13/116 (11%)
Query: 58 WFKNDKKIHSTTKTT--DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
WFKND+++H+T + D+ + I+ D+ +Q R EA ++E L + + +
Sbjct: 5464 WFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKL-TVLEGDPY 5522
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG---IPVQNAPIFDD 168
F K++ V K E L C+ + ++ P + W++DG P +NA I D
Sbjct: 5523 FTG---KLQDYTGVEKD--EVILQCEISKADAP--VKWFKDGKEIKPSKNAVIKAD 5571
Score = 34.7 bits (76), Expect = 1.4
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 9/94 (9%)
Query: 451 KLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVL 508
K DV P +++T+T+V V+L W P +DGG + + Y I R S +++ +
Sbjct: 6690 KYDVPGPP---LNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRD--KTSIRWDTAM 6744
Query: 509 PKHATNF--TVHGLEKNTDYIFSVMAINKIGQSK 540
A + TV + + +Y F V A N+IG K
Sbjct: 6745 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGK 6778
Score = 34.7 bits (76), Expect = 1.4
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 455 TSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA 512
T P L V + + S+ L W+ P DGG + + Y + R+ D + E K
Sbjct: 22046 TEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHTKQL 22104
Query: 513 TNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
T FTV L + T+Y F V A N G S+ R
Sbjct: 22105 T-FTVERLVEKTEYEFRVKAKNDAGYSEPR 22133
Score = 34.7 bits (76), Expect = 1.4
Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 7/86 (8%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G+ R C P P+ TW + G L +TS + H+ Y S I++V SD
Sbjct: 26078 GESARFSCDTDGEPVPTVTWLRKGQVL--STSAR-----HQVTTTKYKSTFEISSVQASD 26130
Query: 432 YGSYECGARNELGFSTTTVKLDVTSA 457
G+Y N G L + A
Sbjct: 26131 EGNYSVVVENSEGKQEAEFTLTIQKA 26156
Score = 34.3 bits (75), Expect = 1.8
Identities = 66/301 (21%), Positives = 110/301 (36%), Gaps = 36/301 (11%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P IT W KD + + ++ T+++ DAG YT A G V+
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMS--DAGKYTVVA----GGNVST 3091
Query: 253 ISVSVH-YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID---PKSV 308
+ V I+S+ + V + AV+ + + A W + G +I+ +
Sbjct: 3092 AKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAH---WYKDGIEINFQVQERH 3148
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DTSPNFVK 366
+ + + I + + + G + V S T + + P++ + P V+
Sbjct: 3149 KYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT---LYVNAPEPPQVLQELQPVTVQ 3205
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
S G+ R P P +W K L K+ +D YT LL+
Sbjct: 3206 S----GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-----HDGQEYT--LLLIE 3254
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDV----TSAPDQ---VVSLTVTNVTHSTVTLEWV 479
D Y C A+N+ G +TT+ L V +PDQ V + TVT E
Sbjct: 3255 AFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQ 3314
Query: 480 P 480
P
Sbjct: 3315 P 3315
Score = 34.3 bits (75), Expect = 1.8
Identities = 25/121 (20%), Positives = 48/121 (39%), Gaps = 3/121 (2%)
Query: 420 SVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV 479
S L + + D+G Y N+ G + + V P ++ ++ ++V +W
Sbjct: 8267 SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWE 8326
Query: 480 PGFDGG---LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKI 536
P D G + ++ + K DS ++V L + +Y+F V A N+
Sbjct: 8327 PPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 8386
Query: 537 G 537
G
Sbjct: 8387 G 8387
Score = 34.3 bits (75), Expect = 1.8
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPK 510
D P + + + T +++TL W P +DGG + Y + K D +++ V P+
Sbjct: 17418 DPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA--DEEEWQIVTPQ 17475
Query: 511 ---HATNFTVHGLEKNTDYIFSVMAINKIG 537
T F + L ++ +Y V A+NK+G
Sbjct: 17476 TGLRVTRFEISKLTEHQEYKIRVCALNKVG 17505
Score = 33.9 bits (74), Expect = 2.4
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 7/97 (7%)
Query: 374 VGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYG 433
V + K P P+ W+K+G + KY K L I+ TSD G
Sbjct: 26371 VAKFAVKATGEPRPTAIWTKDGKA--ITQGGKYKLSEDKGGFF-----LEIHKTDTSDSG 26423
Query: 434 SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
Y C +N G +++ KL + + D T T
Sbjct: 26424 LYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKT 26460
Score = 33.5 bits (73), Expect = 3.2
Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 11/99 (11%)
Query: 360 TSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
T P V NV G+ L C P+P+ TW + + + +S + F
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQ--IESSIDFQITFQSG-- 950
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ L+I D G + C A NE G +T+ L V
Sbjct: 951 ---IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 33.5 bits (73), Expect = 3.2
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C+ P P W K+GV P+ T +Y ++K T L+I+ D G Y
Sbjct: 1057 CQVGGNPKPHVYWKKSGV--PLTTGYRYKVSYNKQ---TGECKLVISMTFADDAGEYTIV 1111
Query: 439 ARNELGFSTTTVKL 452
RN+ G ++ + L
Sbjct: 1112 VRNKHGETSASASL 1125
Score = 33.5 bits (73), Expect = 3.2
Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 7/99 (7%)
Query: 449 TVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQSWYRIRYRKVFD------DS 501
T D PD + L + +T +TV L W P DGG + I +D ++
Sbjct: 9506 TTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEA 9565
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
++ + FTV L + +Y F V A+N G SK
Sbjct: 9566 WRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSK 9604
Score = 33.5 bits (73), Expect = 3.2
Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 5/86 (5%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA 512
V APDQ + VT VT + + W DGG + Y + R+ + P H
Sbjct: 10514 VPDAPDQPI---VTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHP 10570
Query: 513 -TNFTVHGLEKNTDYIFSVMAINKIG 537
T F V L + Y F V A N+IG
Sbjct: 10571 YTKFRVPDLLEGCQYEFRVSAENEIG 10596
Score = 33.5 bits (73), Expect = 3.2
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK--HATNFTVHGLE 521
VT +T +++T+ W P DGG S Y + R S + VL + T V GL
Sbjct: 20577 VTKITKNSMTVVWSRPIADGGSDISGYFLEKRD--KKSLGWFKVLKETIRDTRQKVTGLT 20634
Query: 522 KNTDYIFSVMAINKIGQSKY 541
+N+DY + V A+N GQ +
Sbjct: 20635 ENSDYQYRVCAVNAAGQGPF 20654
Score = 33.5 bits (73), Expect = 3.2
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Query: 5 KDSGIFKCMINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKK 64
+ SGI M + PP Y G + +G ++ + G P+ +TWFK+ +
Sbjct: 21445 QSSGII--MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL-VQGRPVPRVTWFKDGVE 21501
Query: 65 IHS--TTKTTDKAVSAEISILTNVTDNQAQYRCEATNSA 101
I + TD S + + D++ Y EA N++
Sbjct: 21502 IEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 21540
Score = 33.1 bits (72), Expect = 4.2
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 414 DHITYTSVLLINNVATSDY-GSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHS 472
D TYT L+I+ V T D+ G Y C A N+ G + T+ KL V V+ + +
Sbjct: 4292 DQNTYT--LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPL--- 4346
Query: 473 TVTLEWVPGFDGGLQSWYRIRYR 495
V L + F +QS +R++
Sbjct: 4347 EVALGHLAKFTCEIQSAPNVRFQ 4369
Score = 33.1 bits (72), Expect = 4.2
Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRK----VFDDSYKYEDVLPKHATNFTVHGL 520
VT+VT STV+L W P +DGG + I RK V D + + FTV L
Sbjct: 22450 VTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTAL 22509
Query: 521 EKNTDYIFSVMAINKIG 537
+ Y F V+A N G
Sbjct: 22510 SEGDTYEFRVLAKNAAG 22526
Score = 32.7 bits (71), Expect = 5.5
Identities = 57/249 (22%), Positives = 94/249 (37%), Gaps = 25/249 (10%)
Query: 218 IISEGS--MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPN 275
+I++G +L + T D G Y V GAA A ++V I ++
Sbjct: 6102 VIADGKKRVLVVKDATLQDMGTY----VVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQ 6157
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
++ V +C A KW R I D K+L L IR A ++ N+
Sbjct: 6158 QEVVFNCEVNTEGAKA---KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNV 6214
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSK 393
+ N G K LIV+ + P +K + + CK + + W+K
Sbjct: 6215 SLTNHRGENVKSAANLIVEEEDLRIVEP--LKDIETMEKKSVTFWCKVNRLNV-TLKWTK 6271
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
NG ++P + Y + +K+ +L I + D G Y A G + +L
Sbjct: 6272 NGEEVPFDNRVSYRVDKYKH-------MLTIKDCGFPDEGEYIVTA----GQDKSVAELL 6320
Query: 454 VTSAPDQVV 462
+ AP + V
Sbjct: 6321 IIEAPTEFV 6329
Score = 32.3 bits (70), Expect = 7.3
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Query: 466 VTNVTHSTVTLEWVP-GFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
VT+ + +T+ LEW P F+GG + Y + + V + + +TV + +
Sbjct: 8513 VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREG 8572
Query: 524 TDYIFSVMAINKIGQSKYRPDDTKATTLTSSE 555
DY V A+N G+ P +T+ T+ +
Sbjct: 8573 ADYKLRVSAVNAAGEGP--PGETQPVTVAEPQ 8602
Score = 32.3 bits (70), Expect = 7.3
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
V+NVT +T T+ W P DGG + + Y + R+ + P V GL++
Sbjct: 14083 VSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEG 14142
Query: 524 TDYIFSVMAINKIG 537
+ Y F V A N+ G
Sbjct: 14143 STYEFRVSAENRAG 14156
Score = 32.3 bits (70), Expect = 7.3
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 11/135 (8%)
Query: 130 LKPGIE---ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT--VGIENEPLII 184
LKPG+ + A P ++ + AP D + T + E + +
Sbjct: 20735 LKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQV 20794
Query: 185 SVRADGNPPSITYTWTKDGLPI-TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAV 243
+ G PP T TW KD + + + YS N S+L + ++TR+D G Y
Sbjct: 20795 LIPFKGRPPP-TVTWRKDEKNLGSDARYSIENT---DSSSLLTIPQVTRNDTGKYILTIE 20850
Query: 244 NSQGAAVAN-ISVSV 257
N G ++ +SV V
Sbjct: 20851 NGVGEPKSSTVSVKV 20865
Score = 31.9 bits (69), Expect = 9.7
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TWTK + + Q + + + + S + + R D G Y EAVN G A A
Sbjct: 7221 PEPKITWTKADMILKQDKRITIEN--VPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAV 7278
Query: 253 ISVSV 257
+ V+V
Sbjct: 7279 VEVNV 7283
>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 80.2 bits (189), Expect = 3e-14
Identities = 100/402 (24%), Positives = 160/402 (39%), Gaps = 41/402 (10%)
Query: 170 TSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMT 228
T + G+ +A G+P P I W K G ++ + + GS+L +
Sbjct: 29 TPVDQTGVSGGVASFICQATGDPRPKIV--WNKKGKKVSNQRFEV-IEFDDGSGSVLRIQ 85
Query: 229 KL-TRHDAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVL 280
L T D IY C A N+ G + ++V P G ++ Q V A +
Sbjct: 86 PLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATM 145
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLI----IRKAKSENLGNFQCVV 336
C A GNP I W + +D + K L S I I +++ + G ++CV
Sbjct: 146 LCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVA 203
Query: 337 NNGIGSATKQDVMLIVKFK--PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKN 394
N G+ L V+ + P + P G V + C P P W
Sbjct: 204 TNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVN-ITCVAVGSPMPYVKWMLG 262
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
L ++D +VL +N+V S +Y C A + LG ++ V
Sbjct: 263 AEDLTP-----------EDDMPIGRNVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITV 309
Query: 455 TSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYR-KVFDDSYKYEDVLPKHAT 513
+ P + VT T +++TL W G + S+Y I+++ K ++ YK D + T
Sbjct: 310 KALPKPPGTPVVTESTATSITLTWDSGNPEPV-SYYIIQHKPKNSEELYKEIDGVA--TT 366
Query: 514 NFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSE 555
++V GL +DY F V+A+N IG+ P T TS +
Sbjct: 367 RYSVAGLSPYSDYEFRVVAVNNIGRG---PPSEPVLTQTSEQ 405
Score = 45.2 bits (102), Expect = 0.001
Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Query: 18 SDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVS 77
+D + P T T +G V C +TG +P + W K KK+ + +
Sbjct: 18 TDAETPPRFTRTPVDQTGVSGGVASFICQATG-DPRPKIVWNKKGKKVSNQRFEVIEFDD 76
Query: 78 AEISILT----NVTDNQAQYRCEATNSATEIPLFETVT-LNVHFAPEA---VKVRAEPDV 129
S+L ++A Y C A+N+ EI + +T L P + + + V
Sbjct: 77 GSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKV 136
Query: 130 LKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
++ AT++C +AS NP ++W++D +PV +
Sbjct: 137 VERTRTATMLC-AASGNPDPEITWFKDFLPVDTS 169
Score = 36.3 bits (80), Expect = 0.45
Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 11/112 (9%)
Query: 348 VMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTS 403
++L + + +T P F ++ + G V +C+ P P W+K G K+ S
Sbjct: 10 LLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKV----S 65
Query: 404 TKYFAEFHKNDHITYTSVLLINNVAT-SDYGSYECGARNELGFSTTTVKLDV 454
+ F +D SVL I + T D YEC A N +G + + +L V
Sbjct: 66 NQRFEVIEFDD--GSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Score = 35.5 bits (78), Expect = 0.79
Identities = 33/138 (23%), Positives = 54/138 (39%), Gaps = 10/138 (7%)
Query: 47 STGGNPLATLTWFKNDKKIHSTTKTTD-KAVSAE----ISILTNVTDNQAQYRCEATNSA 101
+ GNP +TWFK+ + ++ K + +E + I + +Q +Y C ATNSA
Sbjct: 148 AASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSA 207
Query: 102 -TEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWW---RDG 157
T + + V P + + PG + C + S P + W D
Sbjct: 208 GTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGS-PMPYVKWMLGAEDL 266
Query: 158 IPVQNAPIFDDTTSYNTV 175
P + PI + N V
Sbjct: 267 TPEDDMPIGRNVLELNDV 284
>BC074742-1|AAH74742.1| 344|Homo sapiens opioid binding
protein/cell adhesion molecule-like protein.
Length = 344
Score = 80.2 bits (189), Expect = 3e-14
Identities = 55/220 (25%), Positives = 92/220 (41%), Gaps = 17/220 (7%)
Query: 233 HDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
+D G YTC + + + V P I ++S ++ N L C AIG
Sbjct: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRS--EP 165
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIV 352
+ W + K F ++ YL I K + G ++C N + + + V + V
Sbjct: 166 TVTWRH----LSVKGQGFVSED--EYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 219
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + + N + +VGQ G L C+ +VP F W K +L + +
Sbjct: 220 NYPPYISKAKN---TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG------LDGMR 270
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
++ S L NV+ DYG+Y C A N+LG + ++ L
Sbjct: 271 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 310
Score = 53.6 bits (123), Expect = 3e-06
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 206 ITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAA-VANISVSVHYPAGIK 264
+T S +SE L ++ + R +G Y C A+N A V + ++V+YP I
Sbjct: 167 VTWRHLSVKGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI- 225
Query: 265 SVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDP--KSVTFEPKNLTSYLIIR 322
S ++N + + +LSC A P +AE +W ++ ++ + E K S L
Sbjct: 226 SKAKNTGVSVGQKGILSCEASAVP-MAE-FQWFKEETRLATGLDGMRIENKGRMSTLTFF 283
Query: 323 KAKSENLGNFQCVVNNGIGS 342
++ GN+ CV N +G+
Sbjct: 284 NVSEKDYGNYTCVATNKLGN 303
>AY358132-1|AAQ88499.1| 352|Homo sapiens DMML2433 protein.
Length = 352
Score = 79.8 bits (188), Expect = 4e-14
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 20/224 (8%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D G YTC + ++V P I +S ++ N + L+C A G P
Sbjct: 110 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKP--EPS 167
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W I P + FE YL I + G ++C N + + V ++V
Sbjct: 168 ISWRH----ISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENAVSFPDVRKVKVVVN 220
Query: 354 FKPEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
F P + +KS + G+ G + C+ VP P+F W K KL N +
Sbjct: 221 FAPTIQE----IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIIIQ--- 272
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ + S+L + NV +G+Y C A N+LG + ++ L+ S
Sbjct: 273 --NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 314
Score = 51.2 bits (117), Expect = 1e-05
Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 6/153 (3%)
Query: 194 SITYTWTKDGLPITQSSYS--SGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG-AAV 250
++T T G P S+ S + + G L++ +TR AG Y C A N+ V
Sbjct: 153 NVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENAVSFPDV 212
Query: 251 ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-EHIKWERKGYKIDPKSVT 309
+ V V++ I+ + V P ++ C G P A E K E+K + + +
Sbjct: 213 RKVKVVVNFAPTIQEIKSGTV-TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN-GQQGII 270
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
+ + S L + E+ GN+ CV N +G+
Sbjct: 271 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 303
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 79.4 bits (187), Expect = 5e-14
Identities = 82/316 (25%), Positives = 130/316 (41%), Gaps = 17/316 (5%)
Query: 264 KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTF---EPKNLTSYLI 320
K +N+ +A L C G+P +KW R+G +I + + E K LI
Sbjct: 24434 KEELRNLNVRYQSNATLVCKVTGHP--KPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 24491
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLI-VKFKPEMDTSPNFVKSASNV-GQVGRLM 378
I ++ +Q N GS + + + V K + + + + + G+V +
Sbjct: 24492 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIK 24551
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
P P TW K G L ++ + Y ++ +TS++ N V D G Y
Sbjct: 24552 IPFSGKPDPVITWQK-GQDL-IDNNGHYQVIVTRS----FTSLVFPNGVERKDAGFYVVC 24605
Query: 439 ARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
A+N G TV+LDV PD + V++ + +V L W P DGG + I K
Sbjct: 24606 AKNRFGIDQKTVELDVADVPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYI-VEKC 24664
Query: 498 FDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVG 557
+ ++ V T +TV L T Y F V+A NK G SK P + T+T +
Sbjct: 24665 ATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSK--PSEPSEPTITKEDKT 24722
Query: 558 ELSTVSTEYVETPDIS 573
E ET ++S
Sbjct: 24723 RAMNYDEEVDETREVS 24738
Score = 68.5 bits (160), Expect = 9e-11
Identities = 43/161 (26%), Positives = 77/161 (47%), Gaps = 8/161 (4%)
Query: 382 KSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARN 441
++VP P+ +W K+G ++ + KNDHI+ + L + +D G Y N
Sbjct: 7914 RAVPVPTVSWHKDGKEVKASDRLTM-----KNDHIS--AHLEVPKSVRADAGIYTITLEN 7966
Query: 442 ELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDD 500
+LG +T ++ + V P + +++T S+ L W P FDGG + + R+
Sbjct: 7967 KLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR 8026
Query: 501 SYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ ++ ++TV L N +Y F V A+NK+G +Y
Sbjct: 8027 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 8067
Score = 67.3 bits (157), Expect = 2e-10
Identities = 68/283 (24%), Positives = 107/283 (37%), Gaps = 14/283 (4%)
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK-IDPKSVTFEPKNLTSYLI 320
GI+ ++V E A LSC +G PL IKW R G + I + T L
Sbjct: 24037 GIRKEMKDVTTKLGEAAQLSCQIVGRPL--PDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCK 380
+ + E+ G + C+ N +G +L+ P K VG RL
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVM 24154
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
P P+ TW +G KL N+ +H YT +++ N + G Y+
Sbjct: 24155 YIGRPVPAMTWF-HGQKLLQNSEN---ITIENTEH--YTHLVMKNVQRKTHAGKYKVQLS 24208
Query: 441 NELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFD 499
N G + +++ PD+ + + + ++ + W P D G SW + +
Sbjct: 24209 NVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG-GSWITNYVVEKCE 24267
Query: 500 DSYKYEDVLPKHATNFT---VHGLEKNTDYIFSVMAINKIGQS 539
E L A + T + L +N Y F V A N G S
Sbjct: 24268 AKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGIS 24310
Score = 66.5 bits (155), Expect = 4e-10
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT-YTSVLLINNVATSDYGSY 435
++ K K VP P+ TW K K P N + + H N + T L+I SD G Y
Sbjct: 9639 IVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY-DTHVNKLVVDDTCTLVIPQSRRSDTGLY 9697
Query: 436 ECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRI 492
A N LG ++ ++L+V P V + +V+ +TL W P DGG + + Y I
Sbjct: 9698 TITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVI 9757
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ ++ + PK T +T+ L + +Y+F +MA NK G
Sbjct: 9758 EKREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMAQNKYG 9801
Score = 63.7 bits (148), Expect = 3e-09
Identities = 61/239 (25%), Positives = 101/239 (42%), Gaps = 18/239 (7%)
Query: 306 KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN--GIGS-ATKQDVMLIVK-FKPEMDTS 361
K T +T + ++ +++ NF+ N G+G A DV ++ + P+ +
Sbjct: 14224 KDTTGTALRITQF-VVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELD 14282
Query: 362 PNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
++ G R+ K PAP TW+K+ + L K A + T
Sbjct: 14283 AELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL------KNRANIENTESFT--- 14333
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-V 479
+L+I D G + N G + V + V P V++L T++T +VTL W +
Sbjct: 14334 LLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDL 14393
Query: 480 PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
P DGG + + Y + R+ SY H + V GL + +Y F VMA N+ G
Sbjct: 14394 PLIDGGSRITNYIVEKREATRKSYSTATT-KCHKCTYKVTGLSEGCEYFFRVMAENEYG 14451
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/170 (27%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 371 VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATS 430
VGQ R++ + K P P TW+K G L + + + L I +
Sbjct: 11425 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE-------LQIKEAVRA 11477
Query: 431 DYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFD-GGLQ-S 488
D+G Y A+N G + + ++V P +L VTNVT T+ W D GG + +
Sbjct: 11478 DHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEIT 11537
Query: 489 WYRIRYRKVFDDSYKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIG 537
+ + YRK + K ++ T + L N +Y F V A NK+G
Sbjct: 11538 NFIVEYRK---PNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG 11584
Score = 61.7 bits (143), Expect = 1e-08
Identities = 53/200 (26%), Positives = 83/200 (41%), Gaps = 17/200 (8%)
Query: 356 PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D NF ++ G RL + P P+ WSK L + A+ H D
Sbjct: 21858 PELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR------ADIHTTD 21911
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S L + N +D G Y N G + T + V P +T +VT +
Sbjct: 21912 SF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSA 21968
Query: 475 TLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATN--FTVHGLEKNTDYIFSVM 531
TL W P DGG + + + ++ + S + V+ + T F V+ L + Y F V
Sbjct: 21969 TLMWDAPLLDGGARIHHYVVEKR--EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22026
Query: 532 AINK--IGQSKYRPDDTKAT 549
A+N+ +G+ P+ AT
Sbjct: 22027 AVNEYGVGEPYEMPEPIVAT 22046
Score = 61.3 bits (142), Expect = 1e-08
Identities = 60/226 (26%), Positives = 98/226 (43%), Gaps = 22/226 (9%)
Query: 356 PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P+++ + + K+ + G RLM P P TWSK G+ L D
Sbjct: 22947 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAII---------D 22997
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S+L+++ V D G Y A N+ G + TV + V P S+ V V+ +V
Sbjct: 22998 TTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSV 23057
Query: 475 TLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVM 531
T+ W +P DGG + Y + R+ ++K V K T + + GL + T + F V+
Sbjct: 23058 TITWEIPTIDGGAPINNYIVEKREAAMRAFK--TVTTKCSKTLYRISGLVEGTMHYFRVL 23115
Query: 532 AINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVI 577
N G + P +T L V E+ V + +E D++K +
Sbjct: 23116 PENIYGIGE--PCETSDAVL----VSEVPLVPAK-LEVVDVTKSTV 23154
Score = 60.9 bits (141), Expect = 2e-08
Identities = 63/236 (26%), Positives = 92/236 (38%), Gaps = 21/236 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFK-----PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVP 385
F+ N +G ++ +K K PE+D + K G RL + P
Sbjct: 12078 FRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRP 12137
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF 445
AP TW K G+ V + D + + L+I N D G Y N G
Sbjct: 12138 APKVTWRKVGIDNVVRKG--------QVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGE 12189
Query: 446 STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYK 503
V + V P V L V++VT ++ + W P DGG Q + Y + R+ D
Sbjct: 12190 KAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREA--DRKT 12247
Query: 504 YEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGE 558
+ V P+ T+F V L +Y F V A+N+ G P D L S + E
Sbjct: 12248 WSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGV--PTDVPKPVLASDPLSE 12301
Score = 59.7 bits (138), Expect = 4e-08
Identities = 58/226 (25%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 321 IRKAKSENLGNFQ-CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKSAS-NVGQV 374
+ K K NF+ C +N+ G+G ++ + + PE++ + K
Sbjct: 18568 VTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT 18627
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
RL K P P W K L + + F ++L+I+NV D G
Sbjct: 18628 LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSF---------TMLVIDNVTRFDSGR 18678
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRI 492
Y N G T V + V +P V+LT+ V +VTL W P DGG + + Y +
Sbjct: 18679 YNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIV 18738
Query: 493 RYRKVFDDSY-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ +Y + K T F + L++ Y F V+A N+ G
Sbjct: 18739 EKRETTRKAYATITNNCTK--TTFRIENLQEGCSYYFRVLASNEYG 18782
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT------VKLDVTSAPDQVVSL 464
H IT T + V ++Y + A+N++G S T+ V D P Q L
Sbjct: 23882 HNKTQITTTMYTVTGLVPDAEY-QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGEL 23940
Query: 465 TVTNVTHSTVTLEWV-PGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
+ +++ +VTL+W P DGG + Y + YR+ D ++K + FT+ GL +
Sbjct: 23941 EILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLE 24000
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTK-ATTLTSSEV----GELSTVSTEYVETPDISKPVI 577
T+Y F V A N+ G S+ R T LTS E E+ V+T+ E +S ++
Sbjct: 24001 ATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIV 24060
Score = 58.8 bits (136), Expect = 7e-08
Identities = 51/187 (27%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 357 EMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
E D P F + VGQ ++ P P+ TW+K+G LP+ +T+ + D +
Sbjct: 16732 EPDVKPAFSSYSVQVGQDLKMEVPISGRPKPTITWTKDG--LPLKQTTR----INVTDSL 16785
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVT 475
T+ L I D G Y N +G T ++++ PD + +V+ ++T
Sbjct: 16786 DLTT-LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 16844
Query: 476 LEWVPG-FDGGLQSWYRIRYRKVFDDSYKYEDVLPKHA--TNFTVHGLEKNTDYIFSVMA 532
L W P + GG Q I ++ D + DV+ T V L+ T+Y F + A
Sbjct: 16845 LSWNPPLYTGGCQITNYIVQKR--DTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFA 16902
Query: 533 INKIGQS 539
N+ GQS
Sbjct: 16903 ENRYGQS 16909
Score = 56.8 bits (131), Expect = 3e-07
Identities = 50/189 (26%), Positives = 69/189 (36%), Gaps = 13/189 (6%)
Query: 356 PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+ N + VG RL K VP P TW K P + D
Sbjct: 10719 PELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA---------RID 10769
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S L I N A D G Y N G T +VK+ V P L V+ + +
Sbjct: 10770 VTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSC 10829
Query: 475 TLEWVPGFD--GGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMA 532
L W D G + + Y + R V + K ++F H L + Y+F V A
Sbjct: 10830 YLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH-LNEGNQYLFRVAA 10888
Query: 533 INKIGQSKY 541
N+ G+ +
Sbjct: 10889 ENQYGRGPF 10897
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G R + VP P+ W+ +G + + T Y E D+ ++SVL I N D
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSE--IKTDEHYTVE---TDN--FSSVLTIKNCLRRD 11080
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQSW- 489
G Y+ N G T V L V P + + +VT +T+ W P D G
Sbjct: 11081 TGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVI 11140
Query: 490 -YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
Y + + D++ T + L+K +Y+F V A NKIG
Sbjct: 11141 NYIVEKQDTRKDTWGVVS-SGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11188
Score = 56.0 bits (129), Expect = 5e-07
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 18/225 (8%)
Query: 321 IRKAKSENLGNFQ-CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKSAS-NVGQV 374
+ K ++ NF+ C +N G+G +IV+ K P++D K + G
Sbjct: 16403 VEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGS 16462
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
RL K P P W K V+ + A ++TS L+++NV D G
Sbjct: 16463 LRLFVPIKGRPTPEVKWGK------VDGEIRDAAIIDVTS--SFTS-LVLDNVNRYDSGK 16513
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRI 492
Y N G + V + V P V+L VT +T +V++ W P DGG + Y +
Sbjct: 16514 YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIV 16573
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
R+ SY V H ++ + L++ Y F V A N+ G
Sbjct: 16574 EKREATRKSYA-AVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG 16617
Score = 55.6 bits (128), Expect = 7e-07
Identities = 50/170 (29%), Positives = 67/170 (39%), Gaps = 13/170 (7%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY-FAEFHKNDHITYTSVLLINNVATS 430
G+ RL P P+ WSK+G +L + A+F N L+N +T
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN---------LVNKDSTR 15029
Query: 431 -DYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQS 488
D G+Y A N GF+ + V P L VT VT L W P D G
Sbjct: 15030 RDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAK 15089
Query: 489 WYRIRYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
+K + +V + T V L K +YIF VMA+NK G
Sbjct: 15090 IDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYG 15139
Score = 54.8 bits (126), Expect = 1e-06
Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 6/166 (3%)
Query: 376 RLMCKCKSVPAPSFTWSKNG-VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS 434
R+ K P P +W +G K + E + + +SV++I S G
Sbjct: 9332 RIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGK 9391
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRI 492
Y A+N+ G T ++ V P L V+++T + L W +P DGG + Y I
Sbjct: 9392 YSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVI 9451
Query: 493 RYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
R + D + V P +T F V L Y F V A N+ G
Sbjct: 9452 EKRTI--DGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG 9495
Score = 54.4 bits (125), Expect = 2e-06
Identities = 93/400 (23%), Positives = 158/400 (39%), Gaps = 40/400 (10%)
Query: 20 PPSAP-MITGYVPGTTLAAGTVQKLACISTGGNPLAT-LTWFKNDKKIHSTTK-----TT 72
P SAP IT ++ A+ + KL C+ A +TW+K+ KK+ +
Sbjct: 26216 PVSAPPKITQFLKAE--ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSA 26273
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
D +I+ LT +Q +Y CE + T N+ F +A K E V K
Sbjct: 26274 DGTYELKINNLTE--SDQGEYVCEISGEGG------TSKTNLQFMGQAFKSIHEK-VSK- 26323
Query: 133 GIEATLICDSASSNPPATLSWW-RDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
I T D ++ T + P+ + P+ TV ++ +V+A G
Sbjct: 26324 -ISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKF-AVKATGE 26381
Query: 192 PPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV 250
P T WTKDG ITQ Y D+ G L + K D+G+YTC NS G+
Sbjct: 26382 PRP-TAIWTKDGKAITQGGKYKLSEDK---GGFFLEIHKTDTSDSGLYTCTVKNSAGSVS 26437
Query: 251 ANISVSV----HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
++ +++ A S + P + AV+ L +E IK + +
Sbjct: 26438 SSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS-EAKSQEKL 26496
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
++ E + ++K+ + +L + +V+ I ++ + + + +
Sbjct: 26497 ALKEEASKVLISEEVKKSAATSLE--KSIVHEEITKTSQAS----EEVRTHAEIKAFSTQ 26550
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
+ N GQ RL+ K A W NGV+L + +Y
Sbjct: 26551 MSINEGQ--RLVLKANIAGATDVKWVLNGVELTNSEEYRY 26588
Score = 54.0 bits (124), Expect = 2e-06
Identities = 54/188 (28%), Positives = 83/188 (44%), Gaps = 16/188 (8%)
Query: 356 PEMDTSPNFVKSA-SNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D S + G+ +++ K P P+ TW K+ L + +Y E
Sbjct: 20772 PEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL--GSDARYSIE----- 20824
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGF-STTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ +S+L I V +D G Y N +G ++TV + V P L V +V+ T
Sbjct: 20825 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGT 20884
Query: 474 VTLEWVPG-FDGGLQSWYRIRYRKVFDDSYKYEDVLPKH---ATNFTVHGLEKNTDYIFS 529
VTL W P DGG I Y D+ K + H +T+F + L + T + F
Sbjct: 20885 VTLLWDPPLIDGGSPI---INYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 20941
Query: 530 VMAINKIG 537
V+A N+IG
Sbjct: 20942 VLAENEIG 20949
Score = 53.6 bits (123), Expect = 3e-06
Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 19/232 (8%)
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS-------NV 371
L++ K F+ N G +V +++ K + SP+ AS +
Sbjct: 9983 LVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRL-VSPDLQLDASVRDRIVVHA 10041
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V R++ P P+ TW+ N LP + + A +S ++I N S
Sbjct: 10042 GGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTA---------ISSSMVIKNCQRSH 10092
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQV-VSLTVTNVTHSTVTLEWV-PGFDGGLQSW 489
G Y A+NE G T+ +DV P V N+T+ + L W P DGG
Sbjct: 10093 QGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPIT 10152
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ ++ D N TV GL + Y F + A N IG +
Sbjct: 10153 NYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPF 10204
Score = 53.2 bits (122), Expect = 4e-06
Identities = 42/154 (27%), Positives = 66/154 (42%), Gaps = 8/154 (5%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P TW+K + L + +++ S + I + SD G+Y A N G
Sbjct: 7221 PEPKITWTKADMILKQDKRITI-------ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7273
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYK 503
+T V+++V P + +T+VT+ + L W P DGG + + R+ D
Sbjct: 7274 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVW 7333
Query: 504 YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
++ TNF L N +YIF V A N G
Sbjct: 7334 HKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 7367
Score = 52.4 bits (120), Expect = 6e-06
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ- 487
SD G Y +N G +V + V +P LTV+ VT TL W +P DGG +
Sbjct: 22616 SDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 22675
Query: 488 SWYRIRYRKVFDDSYK-YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ Y + R+ ++ E P ++ V L KN +YIF V A+NK G
Sbjct: 22676 THYIVERRETSRLNWVIVEGECP--TLSYVVTRLIKNNEYIFRVRAVNKYG 22724
Score = 52.0 bits (119), Expect = 8e-06
Identities = 51/205 (24%), Positives = 89/205 (43%), Gaps = 18/205 (8%)
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
++GI ++V IV+F PE +KS ++ R+ + P P TW K+GV
Sbjct: 21446 SSGIIMTRDENVPPIVEFGPEYFDGL-IIKSGESL----RIKALVQGRPVPRVTWFKDGV 21500
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
++ + + ++ ++ L + + G Y A+N G + +K+ V
Sbjct: 21501 EIEKRMNMEI-------TNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21553
Query: 457 APDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQ--SWYRIRYRKVFDDSYK-YEDVLPKHA 512
P +VV + TN+T +TL W + G + Y I R+ ++ ED A
Sbjct: 21554 TPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EA 21611
Query: 513 TNFTVHGLEKNTDYIFSVMAINKIG 537
++T L +Y F V A+NK G
Sbjct: 21612 QSYTAIKLINGNEYQFRVSAVNKFG 21636
Score = 51.6 bits (118), Expect = 1e-05
Identities = 52/204 (25%), Positives = 74/204 (36%), Gaps = 12/204 (5%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G RL K P P TWSK VN + + D T+ L NV D
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPN----VNLRDRIGLDIKSTDFDTF---LRCENVNKYD 13263
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSW- 489
G Y N G T+ + V P +++TV ++ + + W P DGG
Sbjct: 13264 AGKYILTLENSCGKKEYTIVVKVLDTPGPPINVTVKEISKDSAYVTWEPPIIDGGSPIIN 13323
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
Y ++ R S+ T+F V LE+ Y F V A N+ G P +T+
Sbjct: 13324 YVVQKRDAERKSWS-TVTTECSKTSFRVPNLEEGKSYFFRVFAENEYGIGD--PGETRDA 13380
Query: 550 TLTSSEVGELSTVSTEYVETPDIS 573
S G + + V S
Sbjct: 13381 VKASQTPGPVVDLKVRSVSKSSCS 13404
Score = 51.6 bits (118), Expect = 1e-05
Identities = 52/213 (24%), Positives = 82/213 (38%), Gaps = 15/213 (7%)
Query: 332 FQCVVNNGIGSATKQDVMLIVK---FKPEMDTS--PNFVKSASNVGQVGRLMCKCKSVPA 386
F+ N G T ++ ++ + P++D P+ A RL K PA
Sbjct: 13456 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF-RLKIPIKGKPA 13514
Query: 387 PSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFS 446
PS +W K + P+ T T+ E + L++ + SD G Y +N G
Sbjct: 13515 PSVSWKKG--EDPLATDTRVSVE-----SSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13567
Query: 447 TTTVKLDVTSAPD-QVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKVFDDSYKY 504
T+ + V P + VT +TL+W P DGG + I ++ ++
Sbjct: 13568 EGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWV 13627
Query: 505 EDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
T F V L + +Y F V A NK G
Sbjct: 13628 TCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 13660
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/70 (35%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 472 STVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFS 529
+T+T+ WV P FDGG + Y + Y+K D +K + T +T+ GL +Y+F
Sbjct: 19601 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWK-TSIQSLRGTEYTISGLTTGAEYVFR 19659
Query: 530 VMAINKIGQS 539
V ++NK+G S
Sbjct: 19660 VKSVNKVGAS 19669
Score = 51.2 bits (117), Expect = 1e-05
Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 11/160 (6%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ TW K+ V P+ +T+ AE +N+ S+L I + D G Y N G
Sbjct: 15678 PTPAVTWHKDNV--PLKQTTRVNAESTENN-----SLLTIKDACREDVGHYVVKLTNSAG 15730
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
+ T+ + V P + + VT ++TL W P +DGG + Y + R +
Sbjct: 15731 EAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTT 15790
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
++ T L+ +Y F + A N+ G+S Y
Sbjct: 15791 WQIVSATVAR-TTIKACRLKTGCEYQFRIAAENRYGKSTY 15829
Score = 50.8 bits (116), Expect = 2e-05
Identities = 58/212 (27%), Positives = 81/212 (38%), Gaps = 19/212 (8%)
Query: 334 CVVNN-GIGSATKQDVMLIVKFK---PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPS 388
C +N G+G AT + + K PE+D K G R+ K P P
Sbjct: 17499 CALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPMPE 17558
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTT 448
TWS+ ++ + + YT L I+N +D G Y N G +
Sbjct: 17559 ITWSRE--------EGEFTDKVQIEKGVNYTQ-LSIDNCDRNDAGKYILKLENSSGSKSA 17609
Query: 449 TVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRIRYRKVFDDSYKYED 506
V + V P +L V V + L W P DGG + Y I R+ Y +
Sbjct: 17610 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--STRKAYAN 17667
Query: 507 VLPK-HATNFTVHGLEKNTDYIFSVMAINKIG 537
V K T+F V L + Y F VMA N+ G
Sbjct: 17668 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFG 17699
Score = 50.8 bits (116), Expect = 2e-05
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 24/307 (7%)
Query: 160 VQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS-YSSGNDRI 218
+ +AP F + E + ++ + G P S W K+ LPI+ SS S R
Sbjct: 26633 LSDAPAFISQPRSQNIN-EGQNVLFTCEISGEP-SPEIEWFKNNLPISISSNVSISRSRN 26690
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDA 278
+ L + + D+G YT +A N +G A S+ V P ++ S+ VV + D
Sbjct: 26691 VYS---LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV-LPL-VEEPSREVVLRTSGDT 26745
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVT------FEPKNLTSYLIIRKAKSE-NLGN 331
L + + K E S + F + S ++++ E + +
Sbjct: 26746 SLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSS 26805
Query: 332 FQCVVN-NGIGSATKQDVMLIVK-FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
F + N + S+T + + ++ P+++ P+ + + + G+V + C P P
Sbjct: 26806 FMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDI--SIDEGKVLTVACAFTGEPTPEV 26863
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
TWS G K+ ++ E D +T L+I +V D G Y NE G + T
Sbjct: 26864 TWSCGGRKIHSQEQGRFHIE--NTDDLT---TLIIMDVQKQDGGLYTLSLGNEFGSDSAT 26918
Query: 450 VKLDVTS 456
V + + S
Sbjct: 26919 VNIHIRS 26925
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 4/123 (3%)
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTL 476
+YT +L++ NV D G Y N G + V + V P L V VT ++VTL
Sbjct: 15415 SYT-LLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTL 15473
Query: 477 EWVPG-FDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAIN 534
W P DGG + Y + R+ +Y H T++ V L++ Y F V+A N
Sbjct: 15474 TWDPPLLDGGSKIKNYIVEKRESTRKAYS-TVATNCHKTSWKVDQLQEGCSYYFRVLAEN 15532
Query: 535 KIG 537
+ G
Sbjct: 15533 EYG 15535
Score = 50.4 bits (115), Expect = 3e-05
Identities = 54/220 (24%), Positives = 92/220 (41%), Gaps = 19/220 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFK-----PEMDTSPNFVKSASNV--GQVGRLMCKCKSV 384
F+ N G + ++++L V K PE+D NF V G ++
Sbjct: 19948 FRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK-NFPSHTVYVRAGSNLKVDIPISGK 20006
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL-INNVATSDYGSYECGARNEL 443
P P T S++GV P+ + ++ N IT ++ + + T+D G YE A N
Sbjct: 20007 PLPKVTLSRDGV--PLKATMRF------NTEITAENLTINLKESVTADAGRYEITAANSS 20058
Query: 444 GFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDS 501
G + + + V P + ++++T +VTL+W P +DGG Q I ++ +
Sbjct: 20059 GTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTA 20118
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
E T V L +Y F + A N+ G S +
Sbjct: 20119 VWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDH 20158
Score = 50.0 bits (114), Expect = 3e-05
Identities = 53/217 (24%), Positives = 84/217 (38%), Gaps = 19/217 (8%)
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
V+ + + S V A IK+ S + N + VL G A +KW G +
Sbjct: 26524 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG----ATDVKWVLNGVE 26579
Query: 303 I-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
+ + + + L I++A + G C+ G Q + + K E+ +
Sbjct: 26580 LTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSK---ELSDA 26636
Query: 362 PNFVKSAS----NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
P F+ N GQ C+ P+P W KN LP++ S+ +N
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKN--NLPISISSNVSISRSRN---V 26691
Query: 418 YTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
Y+ L I N + SD G Y A+N G + T L V
Sbjct: 26692 YS--LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 49.2 bits (112), Expect = 6e-05
Identities = 55/242 (22%), Positives = 96/242 (39%), Gaps = 15/242 (6%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT--KTTDKAVS 77
P + P + + T+ G L C G P T+TW++ D +I S+ + T ++
Sbjct: 893 PVTPPTLVSGLKNVTVIEGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGI 951
Query: 78 AEISILTNVTDNQAQYRCEATNSATEI--PLFETVTLNVHFAPEAVKVRAE-PDVLKPGI 134
A + I ++ ++ C A N A + + V ++ F E V + K +
Sbjct: 952 ARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFV 1011
Query: 135 EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPS 194
E+ D ++ T G P AP F + +E ++ + GNP
Sbjct: 1012 ESR---DVVMTDTSLTEEQAGPGEPA--APYFITKPVVQKL-VEGGSVVFGCQVGGNPKP 1065
Query: 195 ITYTWTKDGLPITQS-SYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANI 253
Y W K G+P+T Y ++ E ++ ++ DAG YT N G A+
Sbjct: 1066 HVY-WKKSGVPLTTGYRYKVSYNKQTGECKLV-ISMTFADDAGEYTIVVRNKHGETSASA 1123
Query: 254 SV 255
S+
Sbjct: 1124 SL 1125
Score = 49.2 bits (112), Expect = 6e-05
Identities = 49/171 (28%), Positives = 67/171 (39%), Gaps = 10/171 (5%)
Query: 370 NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVAT 429
+ G+ L + P P WSK+G +L A I T+ L++ +
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWSKDGKELEETA-----ARMEIKSTIQKTT-LVVKDCIR 18276
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGF-DGGLQ 487
+D G Y N G + + + V P L VT VT L W P DGG
Sbjct: 18277 TDGGQYILKLSNVGGTKSIPITVKVLDRPGSPEGPLKVTGVTAEKCYLAWNPPLQDGGAN 18336
Query: 488 -SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
S Y I R+ S+ A N+ V L +YIF VMA+NK G
Sbjct: 18337 ISHYIIEKRETSRLSWTQVST-EVQALNYKVTKLLPGNEYIFRVMAVNKYG 18386
Score = 49.2 bits (112), Expect = 6e-05
Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 382 KSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARN 441
K P + W K+G L T + T TS L I + D G+YE N
Sbjct: 18922 KGRPQATVNWRKDGQTLKETTRVNV------SSSKTVTS-LSIKEASKEDVGTYELCVSN 18974
Query: 442 ELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFD 499
G T + + V P + + V+ ++T+ W P +DGG Q S Y + ++
Sbjct: 18975 SAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTS 19034
Query: 500 DSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
++ T+ + L ++Y F V A N+ G+S Y
Sbjct: 19035 TTWHIVSQAVAR-TSIKIVRLTTGSEYQFRVCAENRYGKSSY 19075
Score = 48.8 bits (111), Expect = 8e-05
Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 356 PEMDTSPNFVKS-ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P + P F + N G+ RL P P+ W + ++ + E D
Sbjct: 17126 PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR----CEIKNTD 17181
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHST 473
+ ++L++ + D G Y A N G + V + V P + VT VT
Sbjct: 17182 ---FKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEK 17238
Query: 474 VTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATN-FTVHGLEKNTDYIFSV 530
+L W P DGG S Y + R+ + V + TN V L + +Y+F +
Sbjct: 17239 CSLTWSPPLQDGGSDISHYVVEKRET--SRLAWTVVASEVVTNSLKVTKLLEGNEYVFRI 17296
Query: 531 MAINKIG 537
MA+NK G
Sbjct: 17297 MAVNKYG 17303
Score = 48.0 bits (109), Expect = 1e-04
Identities = 63/261 (24%), Positives = 107/261 (40%), Gaps = 21/261 (8%)
Query: 286 GNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA-- 343
G+P L+ H++ KG D + V T Y++ R +++ + F+ N G +
Sbjct: 11632 GSPNLSYHVERRLKGSD-DWERVHKGSIKETHYMVDRCVENQ-IYEFRVQTKNEGGESDW 11689
Query: 344 --TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVN 401
T++ V+ KP +D + V + G RL + P P W+K+ +
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVK-AGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11748
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
S + K D +S + SD G Y A N G ++V P V
Sbjct: 11749 RSPRV-----KIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPV 11803
Query: 462 VSLTVTNVTHSTVTLEWVPGFDGG---LQSWY--RIRYRKVFDDSYKYEDVLPKHATNFT 516
+L + +V+ T+ W P D G +Q++ + +++ +Y + P T
Sbjct: 11804 RNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP----GTT 11859
Query: 517 VHGLEKNTDYIFSVMAINKIG 537
V L + +YIF V A NKIG
Sbjct: 11860 VTRLIEGNEYIFRVRAENKIG 11880
Score = 48.0 bits (109), Expect = 1e-04
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIR 493
A NE G + TT + + AP SL + ++T STV+L W P DGG + + Y I
Sbjct: 14446 AENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIE 14505
Query: 494 YRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
++ D + + + V L + +Y F VMA+N G+S R
Sbjct: 14506 AQRKGSDQWTH--ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR 14552
Score = 48.0 bits (109), Expect = 1e-04
Identities = 47/183 (25%), Positives = 71/183 (38%), Gaps = 11/183 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V RL K P P W+K G + +E H + L+I D
Sbjct: 23654 GGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIA-TSETH--------TELVIKEADRGD 23704
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSW 489
G+Y+ N+ G +K+ V +P+ L ++ +V + W P DGG
Sbjct: 23705 SGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23764
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
I R+ + Y T+ V GL++N +Y F V A N+ G SK + T
Sbjct: 23765 GYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23824
Query: 550 TLT 552
T
Sbjct: 23825 PKT 23827
Score = 47.6 bits (108), Expect = 2e-04
Identities = 58/223 (26%), Positives = 92/223 (41%), Gaps = 24/223 (10%)
Query: 237 IYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
+ T + ++G + +H P + +VS+ D V T+I N A+ + W
Sbjct: 4225 VATVKIQEAEGGLIKEDGPMIHTPL-VDTVSEE------GDIVHLTTSITN---AKEVNW 4274
Query: 297 --ERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN-LGNFQCVVNNGIG-SATKQDVMLIV 352
E K D K + +N T L+I K +E+ G + C N G +AT + ++
Sbjct: 4275 YFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 4333
Query: 353 KFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
+ P + ++ A +G + + C+ +S P F W K G + + S K K
Sbjct: 4334 RAAPVIKRKIEPLEVA--LGHLAKFTCEIQSAPNVRFQWFKAGRE--IYESDKCSIRSSK 4389
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVT 455
Y S L I D G Y C A NE G + T L VT
Sbjct: 4390 -----YISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 4427
Score = 47.6 bits (108), Expect = 2e-04
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 4/159 (2%)
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNEL 443
+P P WSKN + T + + T L I D G+Y A N L
Sbjct: 8928 LPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-LSIPKAVREDKGTYTVTASNRL 8986
Query: 444 GFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
G V ++V P +L VT++ + L W P +GG + + Y I R
Sbjct: 8987 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKK 9046
Query: 502 YKYEDVLPKHA-TNFTVHGLEKNTDYIFSVMAINKIGQS 539
++E+V + + L N Y F V A+NK G S
Sbjct: 9047 AEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGIS 9085
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/167 (26%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W K+G P+ +T+ E ++VL I D+G Y A N G
Sbjct: 17842 PRPNISWVKDGE--PLKQTTRVNVE-----ETATSTVLHIKEGNKDDFGKYTVTATNSAG 17894
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVP-GFDGGLQ-SWYRIRYRKVFDDS 501
+T + + V P V + V+ V + W P + GG Q S Y + R +
Sbjct: 17895 TATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTT 17954
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKA 548
+ T + L+ T+Y F + A N+ G+S P D+KA
Sbjct: 17955 WHMVSATVARTT-IKITKLKTGTEYQFRIFAENRYGKS--APLDSKA 17998
Score = 46.8 bits (106), Expect = 3e-04
Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 17/125 (13%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVH-------------YPAGIKSVSQNVVANPNEDAVL 280
DA +YTCEA N G A + S+SV YP I + Q+ V + + A
Sbjct: 3259 DAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARF 3318
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSY-LIIRKAKSENLGNFQCVVNNG 339
C G L + W K KI P + +Y L I +A E+ G + V NN
Sbjct: 3319 QCRVSGTDL---KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNA 3375
Query: 340 IGSAT 344
+G +
Sbjct: 3376 VGQVS 3380
Score = 46.8 bits (106), Expect = 3e-04
Identities = 39/115 (33%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Query: 345 KQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL-PVNTS 403
+ D M +++ PE T P + K+A VG+ R P P TW K+G K+ P +
Sbjct: 25182 RTDTMRLLERPPEF-TLPLYNKTAY-VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDND 25239
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
KY E K + L IN+V T D Y ARN+ G + KL VT P
Sbjct: 25240 KKYTFESDKGLY-----QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP 25289
Score = 46.4 bits (105), Expect = 4e-04
Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 11/148 (7%)
Query: 402 TSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF------STTTVKLDVT 455
T +K +A K+ YT + + + Y + A NE+G S D
Sbjct: 10555 TMSKRWARVTKDPIHPYTKFRVPDLLEGCQY-EFRVSAENEIGIGDPSPPSKPVFAKDPI 10613
Query: 456 SAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHA- 512
+ P V+ + T ++V L W P DGG + Y + Y+KV D+ ++ + P+
Sbjct: 10614 AKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCP 10673
Query: 513 -TNFTVHGLEKNTDYIFSVMAINKIGQS 539
T + V GL Y F V+A+N G+S
Sbjct: 10674 ETKYKVTGLRDGQTYKFRVLAVNAAGES 10701
Score = 46.4 bits (105), Expect = 4e-04
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 13/157 (8%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
PAP+ W K+ +L N ++ T + +LI + + G YE RN +
Sbjct: 20403 PAPTIEWYKDDKELQTNALVCV-------ENTTDLASILIKDADRLNSGCYELKLRNAMA 20455
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSY 502
++ T+++ + P + VT +TL W P DGG + + I ++ + S
Sbjct: 20456 SASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKR--ETSR 20513
Query: 503 KYEDVLPKHATN--FTVHGLEKNTDYIFSVMAINKIG 537
++ +H T + K +YIF V A+NK G
Sbjct: 20514 VVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYG 20550
Score = 46.0 bits (104), Expect = 6e-04
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V+ P L V +VT STVTL W P +DGG + + Y + K + + L
Sbjct: 23134 VSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPT 23193
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATT--LTSSEVGELSTVSTEYVET 569
TV L + Y+F + A N+ G S+ R T T L +LST+ + +
Sbjct: 23194 VLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 23253
Query: 570 PDISKPVIVYVSLTG 584
P +PV + + + G
Sbjct: 23254 P-AGRPVELVIPIAG 23267
Score = 46.0 bits (104), Expect = 6e-04
Identities = 40/172 (23%), Positives = 70/172 (40%), Gaps = 16/172 (9%)
Query: 293 HIKWERKGYKIDP----KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
H+ W + G KI P K TFE L I +++ + V N G + +
Sbjct: 25223 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 25282
Query: 349 MLIVKFKPEMDTS--PNFVKSASNVG-QVGRLMC---KCKSVPAPSFTWSKNGVKLPVNT 402
+ + P D++ P F + +N Q G+ +C + +P P+ W K+G L +
Sbjct: 25283 LTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGP 25342
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ + ++ + Y + L I + D G Y A N G ++ L V
Sbjct: 25343 NIEII-----HEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 45.6 bits (103), Expect = 7e-04
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Query: 172 YNTVGIE-NEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTK 229
+NT I+ E L I + G P P+I+ W KDG P+ Q++ + + S ++L++ +
Sbjct: 17821 FNTYSIQAGEDLKIEIPVIGRPRPNIS--WVKDGEPLKQTTRVNVEETATS--TVLHIKE 17876
Query: 230 LTRHDAGIYTCEAVNSQGAAVANISVSV 257
+ D G YT A NS G A N+SV V
Sbjct: 17877 GNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 45.6 bits (103), Expect = 7e-04
Identities = 39/161 (24%), Positives = 65/161 (40%), Gaps = 13/161 (8%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W G KL S + E H T + L I D G Y +N G
Sbjct: 23269 PPPAASWFFAGSKL--RESERVTVETH-----TKVAKLTIRETTIRDTGEYTLELKNVTG 23321
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
++ T+K+ + P + + + +++T+ W P DGG S Y + R
Sbjct: 23322 TTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPG 23381
Query: 502 Y-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ + + + FT L + +Y+F V A N+ G Y
Sbjct: 23382 WLPVSESVTRSTFKFT--RLTEGNEYVFRVAATNRFGIGSY 23420
Score = 45.2 bits (102), Expect = 0.001
Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 168 DTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLN 226
D +++ + IE E L I V P T +W KDG + S + ND I + L
Sbjct: 7893 DLETHDIIVIEGEKLSIPVPFRAVPVP-TVSWHKDGKEVKASDRLTMKNDHISAH---LE 7948
Query: 227 MTKLTRHDAGIYTCEAVNSQGAAVANISVSV 257
+ K R DAGIYT N G+A A+I+V V
Sbjct: 7949 VPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 44.8 bits (101), Expect = 0.001
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 6/148 (4%)
Query: 395 GVKLPVNTSTKYFAEFHKN----DHITYTSVLLINNVATSDYGSYECGARNELGFSTTTV 450
G +P TK E K+ D++ S L+I + D+G Y A N G
Sbjct: 8633 GRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAA 8692
Query: 451 KLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKVFDDSYKYEDVLP 509
+++V P V+ L L W P DGG + I RK + + +
Sbjct: 8693 RVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERK-DAKMHTWRQPIE 8751
Query: 510 KHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ + GL + +Y F V+A NK G
Sbjct: 8752 TERSKCDITGLLEGQEYKFRVIAKNKFG 8779
Score = 44.8 bits (101), Expect = 0.001
Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 13/170 (7%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G+V ++ P P +W+K+G+++ T+ + ++H ++L + + D
Sbjct: 19307 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEIIST---DNH----TLLTVKDCIRRD 19359
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWV-PGFDGGLQSW 489
G Y +N G + V V P L + +T +L W P DGG
Sbjct: 19360 TGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 19419
Query: 490 YRIRYRKVFDDSYKYEDVLPKHA--TNFTVHGLEKNTDYIFSVMAINKIG 537
Y +RK + S+ + T+ V L K +YIF V +NK G
Sbjct: 19420 YY--HRKKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYG 19467
Score = 44.4 bits (100), Expect = 0.002
Identities = 85/372 (22%), Positives = 144/372 (38%), Gaps = 38/372 (10%)
Query: 190 GNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGA 248
G P P + +T KD +T+S + R ++ S ++TK R D G Y A N+ G+
Sbjct: 11730 GKPFPEVAWTKDKDATDLTRSPRVKIDTR--ADSSKFSLTKAKRSDGGKYVVTATNTAGS 11787
Query: 249 AVANISVSV-HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGY---KID 304
VA +V+V P ++++ + + + D CT +P + E + Y K +
Sbjct: 11788 FVAYATVNVLDKPGPVRNLK---IVDVSSD---RCTVCWDP-PEDDGGCEIQNYILEKCE 11840
Query: 305 PKSV---TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA-TKQDVMLIVKFKPEMDT 360
K + T+ LT + + N F+ N IG+ + +I K K +
Sbjct: 11841 TKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPG 11900
Query: 361 SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF-HKNDHITYT 419
P+ V +V + P P + K+ + K+ + N
Sbjct: 11901 RPD----PPEVTKVSKEEMTVVWNP-PEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE 11955
Query: 420 SVLLINNVATSDYGSYECGARNELGF------STTTVKLDVTSAPDQVVSLTVTNVTHST 473
+ + N+ + A NE+G S V D P + V + T +
Sbjct: 11956 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHS 12015
Query: 474 VTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHAT------NFTVHGLEKNTD 525
+TL W P +DGG Y + R D+ E +A FTV L++N +
Sbjct: 12016 ITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 12075
Query: 526 YIFSVMAINKIG 537
Y F V A N++G
Sbjct: 12076 YEFRVCAQNQVG 12087
Score = 44.4 bits (100), Expect = 0.002
Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 16/161 (9%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P +WSK G + + T+ + +S+L I D G Y A N G
Sbjct: 13910 PLPKSSWSKAGKDIRPSDITQITST-------PTSSMLTIKYATRKDAGEYTITATNPFG 13962
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSY 502
VK+ V P + ++NV+ TL W P DGG Y + R+ +
Sbjct: 13963 TKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLW 14022
Query: 503 KY--EDVLP-KHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
ED+ +H + G +YIF V A+N G+ +
Sbjct: 14023 TVVSEDIQSCRHVATKLIQG----NEYIFRVSAVNHYGKGE 14059
Score = 44.4 bits (100), Expect = 0.002
Identities = 60/227 (26%), Positives = 88/227 (38%), Gaps = 18/227 (7%)
Query: 320 IIRKAKSENLGNFQCVVNNGIG-SATKQDVMLIVKFK---PEMDTSPNFVKSA-SNVGQV 374
++R FQ + N G SA ++ +IVK + PE+D + K + G
Sbjct: 14526 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDN 14585
Query: 375 GRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLL-INNVATSDYG 433
++ P P+ TW K G ++ T F T TS +L IN SD G
Sbjct: 14586 IKVEIPVLGRPKPTVTWKK-GDQILKQTQRVNF-------ETTATSTILNINECVRSDSG 14637
Query: 434 SYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWY 490
Y ARN +G + + V P + V+ VT W P DGG+ S Y
Sbjct: 14638 PYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNY 14697
Query: 491 RIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ R+ D + E T + L +Y F V A N+ G
Sbjct: 14698 VVEMRQT-DSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14743
Score = 44.4 bits (100), Expect = 0.002
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I + + + DD T+ L + V G PP + TW+K G+ + + +
Sbjct: 22944 IEIPDLELADDLKKTVTIRA-GASLRLMVSVSGRPPPVI-TWSKQGIDLASRAIIDTTES 23001
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG 262
S+L + K+ R+DAG YT EA N G A + V V+ G
Sbjct: 23002 Y----SLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG 23042
Score = 44.0 bits (99), Expect = 0.002
Identities = 39/156 (25%), Positives = 60/156 (38%), Gaps = 12/156 (7%)
Query: 306 KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMD-TSPNF 364
+ + E K +S + + + + Q N + + KF E + T P F
Sbjct: 3400 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIF 3459
Query: 365 VKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS 420
+K SN +G V L +P P W NGV L + K+ F +DH
Sbjct: 3460 IKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFV--FDGDDH----- 3512
Query: 421 VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
L+I D G Y C A N+ G + + L + S
Sbjct: 3513 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3548
Score = 43.6 bits (98), Expect = 0.003
Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHA--TNFTVHGLE 521
V + T S+V+L W P +DGG Y + ++ D++ + LP++ T F V GL
Sbjct: 13100 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCN-LPQNLQKTRFEVTGLM 13158
Query: 522 KNTDYIFSVMAINKIGQS 539
++T Y F V A+NKIG S
Sbjct: 13159 EDTQYQFRVYAVNKIGYS 13176
Score = 43.6 bits (98), Expect = 0.003
Identities = 40/155 (25%), Positives = 63/155 (40%), Gaps = 12/155 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ WSK L T+ + D + L I N +D G Y +N L
Sbjct: 19717 PVPNVLWSKPDTDL----RTRAYV-----DTTDSRTSLTIENANRNDSGKYTLTIQNVLS 19767
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSY 502
++ T+ + V P ++TV +VT + L W VP DGG Y I R+ ++
Sbjct: 19768 AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAW 19827
Query: 503 KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ ++ V L++ Y F V N+ G
Sbjct: 19828 -VSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFG 19861
Score = 43.2 bits (97), Expect = 0.004
Identities = 53/215 (24%), Positives = 85/215 (39%), Gaps = 20/215 (9%)
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS---VTFEPKNLTSYLIIRKA 324
Q+VV A G P+ + W R G I + V + + L I
Sbjct: 13 QSVVVLEGSTATFEAHISGFPV--PEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAV 70
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCK 380
N G + NG G AT +L+ K E PNFV+ ++ G RL +
Sbjct: 71 TKANSGRYSLKATNGSGQATSTAELLV---KAET-APPNFVQRLQSMTVRQGSQVRLQVR 126
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
+P P + ++G ++ S+ F + D Y+ LLI D G+Y A
Sbjct: 127 VTGIPNPVVKFYRDGAEIQ---SSLDFQISQEGD--LYS--LLIAEAYPEDSGTYSVNAT 179
Query: 441 NELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVT 475
N +G +T+T +L V + T T V+ + ++
Sbjct: 180 NSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQIS 214
Score = 43.2 bits (97), Expect = 0.004
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Query: 456 SAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHAT 513
+ P++ L V VT +TVTL W P +DGG + Y + R + + + +
Sbjct: 10218 TVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSR 10277
Query: 514 NFTVHGLEKNTDYIFSVMAINKIGQSK 540
+TV GL++ Y + V A+N +GQ K
Sbjct: 10278 KYTVKGLKEGDTYEYRVSAVNIVGQGK 10304
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 12/156 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W K+G L K + +N L + +V D G Y A N G
Sbjct: 12826 PMPTVSWKKDGTLLKPAEGIKMAMQ--RN-----LCTLELFSVNRKDSGDYTITAENSSG 12878
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSY 502
+ T+KL V P S+ + + L W P DGG + + Y + R+ ++
Sbjct: 12879 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 12938
Query: 503 -KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ +P T+ +V L + +Y F + A NK G
Sbjct: 12939 AQVSATVP--ITSCSVEKLIEGHEYQFRICAENKYG 12972
Score = 42.7 bits (96), Expect = 0.005
Identities = 31/80 (38%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 464 LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLE 521
L V N+T +T L+W VP DGG + Y + R V ++ D K T TV L
Sbjct: 7593 LEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLT 7651
Query: 522 KNTDYIFSVMAINKIGQSKY 541
+ + Y+F V A N IGQS Y
Sbjct: 7652 EGSLYVFRVAAENAIGQSDY 7671
Score = 42.7 bits (96), Expect = 0.005
Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 435 YECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRI 492
+ CG E+G + +D P LT T ST+TL+W P +GG Y I
Sbjct: 8778 FGCGPPVEIG---PILAVDPLGPPTSPERLTYTERQRSTITLDWKEPRSNGGSPIQGYII 8834
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
R+ ++ + T+F V L+++ Y F V A+N+IG+S+
Sbjct: 8835 EKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 8882
Score = 42.7 bits (96), Expect = 0.005
Identities = 49/226 (21%), Positives = 88/226 (38%), Gaps = 11/226 (4%)
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV--GQVGR 376
L++ K F+ N +G + ++ + + K ++ + + G+ R
Sbjct: 12361 LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLR 12420
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
+ P P+ W K ++ ++ + A HK D +S+L+I +V D G Y
Sbjct: 12421 IEAHVYGKPHPTCKWKKGEDEV---VTSSHLA-VHKADS---SSILIIKDVTRKDSGYYS 12473
Query: 437 CGARNELGFSTTTVKLDVTSAP-DQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRY 494
A N G T +K+ V AP ++++ +L W +P DGG I
Sbjct: 12474 LTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVE 12533
Query: 495 RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
+ + T+ V L +YIF V A N+ G S+
Sbjct: 12534 KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12579
Score = 42.3 bits (95), Expect = 0.007
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQ-SWYRIRYRKVFDDSYKYEDVLPK 510
D S PD L T +T ++ TL W+P DGG + Y I YR+ + ++ +
Sbjct: 12297 DPLSEPDPPRKLEATEMTKNSATLAWLPPLRDGGAKIDGYIISYREEEQPADRWTEYSVV 12356
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQS 539
+ V GL++ Y F V A N +G S
Sbjct: 12357 KDLSLVVTGLKEGKKYKFRVAARNAVGVS 12385
Score = 42.3 bits (95), Expect = 0.007
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 469 VTHSTVTLEWV-PGFDGG-LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDY 526
V + +TL+W P +DGG + + Y + R + D + T FTV GL ++ Y
Sbjct: 17035 VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRY 17094
Query: 527 IFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVIVYVSLTGAV 586
F V+A N G +P D+ EV EL +S + P ++V T +
Sbjct: 17095 EFRVIAKNAAGAIS-KPSDSTGPITAKDEV-ELPRISMD----PKFRDTIVVNAGETFRL 17148
Query: 587 LVLINVALIACFVWKRRLRRIKEQA 611
++ + W R + I+E A
Sbjct: 17149 EADVHGKPLPTIEWLRGDKEIEESA 17173
Score = 42.3 bits (95), Expect = 0.007
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIR 493
A NE G + TT + V+ P +T+ +VT +T T++W P DGG + + Y +
Sbjct: 18777 ASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVE 18836
Query: 494 YRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
+ S K+ T+ GL +Y+F V A+N+ G+S R
Sbjct: 18837 MQT--KGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPR 18883
Score = 42.3 bits (95), Expect = 0.007
Identities = 54/192 (28%), Positives = 77/192 (40%), Gaps = 18/192 (9%)
Query: 356 PEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
PE+D S + +G L K P PS +W K+G LP+ S F F K +
Sbjct: 21064 PEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDG--LPLKESE--FVRFSKTE 21119
Query: 415 HITYTSVLLINNVATSDYGSYECGARN---ELGFSTTTVKLDVTSAPDQVVSLTVTNVTH 471
+ L I N G Y N + T + L S P + +
Sbjct: 21120 N---KITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRF--DEIKA 21174
Query: 472 STVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA-TNFTVHGLEKNTDYIF 528
+V L W VP +GG + + Y I R+ ++K V A T F V L K+ +Y F
Sbjct: 21175 DSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKM--VCSSVARTTFKVPNLVKDAEYQF 21232
Query: 529 SVMAINKIGQSK 540
V A N+ G S+
Sbjct: 21233 RVRAENRYGVSQ 21244
Score = 41.9 bits (94), Expect = 0.009
Identities = 68/283 (24%), Positives = 112/283 (39%), Gaps = 31/283 (10%)
Query: 270 VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNL--TSYLIIRKAKSE 327
++ E + G P+ + W + G +I+ K + E N+ ++ L +R A +
Sbjct: 21471 LIIKSGESLRIKALVQGRPV--PRVTWFKDGVEIE-KRMNMEITNVLGSTSLFVRDATRD 21527
Query: 328 NLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCK----S 383
+ G + N GSA K ++ + V+ P P ++ + G+ L
Sbjct: 21528 HRGVYTVEAKNASGSA-KAEIKVKVQDTPGKVVGP--IRFTNITGEKMTLWWDAPLNDGC 21584
Query: 384 VPAPSFTWSKNGVKLPVNTSTKYFAEFH-KNDHITYTSVLLINNVATSDYGSYECGARNE 442
P + K TS +A K + +YT++ LIN ++Y + A N+
Sbjct: 21585 APITHYIIEKR------ETSRLAWALIEDKCEAQSYTAIKLING---NEY-QFRVSAVNK 21634
Query: 443 LGF-----STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGG--LQSWYRIRY 494
G S V + PD +N+T +++TL W P DGG +Q + R
Sbjct: 21635 FGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERR 21694
Query: 495 RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
K K P T F V GL + +Y F VMA N G
Sbjct: 21695 EKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21737
Score = 41.5 bits (93), Expect = 0.012
Identities = 44/156 (28%), Positives = 63/156 (40%), Gaps = 11/156 (7%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ W K +L NT+ E D T SV + D G+Y A+N G
Sbjct: 16074 PIPTIQWIKGDQELS-NTAR---LEIKSTDFATSLSV---KDAVRVDSGNYILKAKNVAG 16126
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGF-DGGLQSW-YRIRYRKVFDDS 501
+ TV + V P + ++ VT TL W P DGG Y + R+
Sbjct: 16127 ERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLV 16186
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ D + + LE N +Y F +MA+NK G
Sbjct: 16187 WTVVDANVQTLSCKVTKLLEGN-EYTFRIMAVNKYG 16221
Score = 41.1 bits (92), Expect = 0.016
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 10/125 (8%)
Query: 424 INNVATSDYGSYECGARNELGF-----STTTVKL-DVTSAPDQVVSLTVTNVTHSTVTLE 477
+ +V S+ A+N +G +T VK+ D P V+LT ++ T S+V L+
Sbjct: 6755 VTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLK 6814
Query: 478 WVPGF-DGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAIN 534
W P DGG + + R + D+ + L T + V GLEK Y++ V A N
Sbjct: 6815 WEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELT-YKVTGLEKGNKYLYRVSAEN 6873
Query: 535 KIGQS 539
K G S
Sbjct: 6874 KAGVS 6878
Score = 41.1 bits (92), Expect = 0.016
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 5/108 (4%)
Query: 439 ARNELGF---STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRY 494
A NE G + T + V P +TV +VT ++V+L W P DGG + I
Sbjct: 16612 AENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVE 16671
Query: 495 RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
+ S K+ + + + L + +Y+F V+A+N+ G+S R
Sbjct: 16672 MQA-KHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 16718
Score = 40.3 bits (90), Expect = 0.028
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 9/90 (10%)
Query: 364 FVKSASNVGQVGRLMCKCKS--VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
F+K+ ++ ++ +L C +S + A TW K+G KL N +F +FH + TY
Sbjct: 26226 FLKAEASK-EIAKLTCVVESSVLRAKEVTWYKDGKKLKENG---HF-QFHYSADGTYE-- 26278
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVK 451
L INN+ SD G Y C E G S T ++
Sbjct: 26279 LKINNLTESDQGEYVCEISGEGGTSKTNLQ 26308
Score = 39.9 bits (89), Expect = 0.037
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG 481
L+I+ SD G Y N + + + ++V + P L ++T +V L W P
Sbjct: 6955 LVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPP 7014
Query: 482 FD--GGLQSWYRIRYRKVFDDSY-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
D G + Y + R+V ++ K D + FTV L + +Y+F V A NK G
Sbjct: 7015 DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTD--LEFTVPDLVQGKEYLFKVCARNKCG 7071
Score = 39.5 bits (88), Expect = 0.048
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 172 YNTVGI-ENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTK 229
+NT + E L + V G P P++T W KD +P+ Q+ + N S+L +
Sbjct: 15657 FNTFTVLAGEDLKVDVPFIGRPTPAVT--WHKDNVPLKQT--TRVNAESTENNSLLTIKD 15712
Query: 230 LTRHDAGIYTCEAVNSQGAAVANISVSV 257
R D G Y + NS G A+ ++V V
Sbjct: 15713 ACREDVGHYVVKLTNSAGEAIETLNVIV 15740
Score = 39.1 bits (87), Expect = 0.064
Identities = 82/387 (21%), Positives = 146/387 (37%), Gaps = 30/387 (7%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYT 239
E + G PP T W+KDG + ++ +I + L TR D+G YT
Sbjct: 14980 EAFRLEADVSGRPPP-TMEWSKDGKELEGTAKLE--IKIADFSTNLVNKDSTRRDSGAYT 15036
Query: 240 CEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAI---GNPLLAEHIKW 296
A N G A +V V G V +E VLS G + +I
Sbjct: 15037 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 15096
Query: 297 ERKGYKIDPKSVTFEPKNLTSYLIIRKAK-SENLGNFQCVVNNGIGSATKQDVMLIVKFK 355
+R+ ++ +V E + +T + + K +E + V G+G + + +L V
Sbjct: 15097 KRETSRLAWTNVASEVQ-VTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVN-- 15153
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P P + + + ++C P + V K + K +
Sbjct: 15154 PYGPPDPPKNPEVTTITKDSMVVCWGH----PDSDGGSEIINYIVERRDKAGQRWIKCNK 15209
Query: 416 ITYTSVLL-INNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV------SLTVTN 468
T T + ++ + + A N G S + A D V + V +
Sbjct: 15210 KTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLD 15269
Query: 469 VTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK---HATNFTVHGLEKN 523
+ S++++ W P +DGG + + Y + +D ++ V P AT++T+ GL +N
Sbjct: 15270 TSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI--VTPPAGLKATSYTITGLTEN 15327
Query: 524 TDYIFSVMAINK--IGQSKYRPDDTKA 548
+Y + A+N +G+ P KA
Sbjct: 15328 QEYKIRIYAMNSEGLGEPALVPGTPKA 15354
Score = 38.7 bits (86), Expect = 0.084
Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 18/198 (9%)
Query: 163 APIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISE 221
AP F + V +E G P P ++ W +DG I+ S+ G S+
Sbjct: 5 APTFTQPLQ-SVVVLEGSTATFEAHISGFPVPEVS--WFRDGQVISTSTL-PGVQISFSD 60
Query: 222 G-SMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH---YPAGIKSVSQNVVANPNED 277
G + L + +T+ ++G Y+ +A N G A + + V P Q++
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQ 120
Query: 278 AVLS--CTAIGNPLLAEHIKWERKGYKIDPKSVTFE--PKNLTSYLIIRKAKSENLGNFQ 333
L T I NP+ +K+ R G +I S+ F+ + L+I +A E+ G +
Sbjct: 121 VRLQVRVTGIPNPV----VKFYRDGAEIQ-SSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 334 CVVNNGIGSATKQDVMLI 351
N +G AT +L+
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 38.7 bits (86), Expect = 0.084
Identities = 59/216 (27%), Positives = 81/216 (37%), Gaps = 32/216 (14%)
Query: 260 PAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS-VTFEPKNLTSY 318
P IK VS N + + A LS T IG P I+W G + P + F
Sbjct: 3457 PIFIKEVS-NADISMGDVATLSVTVIGIP--KPKIQWFFNGVLLTPSADYKFVFDGDDHS 3513
Query: 319 LIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI-VKFKPEMDTS---------------- 361
LII K E+ G + C+ +N G + I K + DT
Sbjct: 3514 LIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 3573
Query: 362 -PNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
P+F+K + G PAP+ TW K +L TS Y + N
Sbjct: 3574 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLC--TSVYYTIIHNPNGSG 3631
Query: 417 TYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
T+ ++N+ D G Y C A N LG ST +L
Sbjct: 3632 TF----IVNDPQREDSGLYICKAENMLGESTCAAEL 3663
Score = 38.7 bits (86), Expect = 0.084
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 180 EPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIY 238
E L I G P P +T W KDG+ I + + ++ S+ + TR G+Y
Sbjct: 21477 ESLRIKALVQGRPVPRVT--WFKDGVEI-EKRMNMEITNVLGSTSLF-VRDATRDHRGVY 21532
Query: 239 TCEAVNSQGAAVANISVSVHYPAG 262
T EA N+ G+A A I V V G
Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTPG 21556
Score = 38.7 bits (86), Expect = 0.084
Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 11/131 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAP 387
F+ N G + + + +K K +P K +V G+ +L C+ P P
Sbjct: 24006 FRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLP 24065
Query: 388 SFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFST 447
W + G +L S KY +D T+T L + D G Y C A NE+G
Sbjct: 24066 DIKWYRFGKELI--QSRKYKMS---SDGRTHT--LTVMTEEQEDEGVYTCIATNEVGEVE 24118
Query: 448 TTVKLDVTSAP 458
T+ KL + + P
Sbjct: 24119 TSSKLLLQATP 24129
Score = 38.3 bits (85), Expect = 0.11
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P T TWTKDGLP+ Q++ + D + + + L++ + + D G Y N G A+
Sbjct: 16760 PKPTITWTKDGLPLKQTTRINVTDSL--DLTTLSIKETHKDDGGQYGITVANVVGQKTAS 16817
Query: 253 ISV 255
I +
Sbjct: 16818 IEI 16820
Score = 37.9 bits (84), Expect = 0.15
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
Query: 193 PSITYTWTKDGLPITQSSYSS-GNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P++ + W K G I +S S + + IS +L T++ D G YTC+A N G+
Sbjct: 4364 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR-TQVV--DCGEYTCKASNEYGSVSC 4420
Query: 252 NISVSVHYPAGIKSVSQNV---VANPNEDAVL 280
+++V P G K V + + P E+ VL
Sbjct: 4421 TATLTVTVPGGEKKVRKLLPERKPEPKEEVVL 4452
Score = 37.9 bits (84), Expect = 0.15
Identities = 58/269 (21%), Positives = 101/269 (37%), Gaps = 19/269 (7%)
Query: 280 LSCTAIGNPLLAEHIKWERKGYKIDP-KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
L T G P+ + W++ G + P + + + L + ++ G++ N
Sbjct: 12818 LDATVFGKPMPT--VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 12875
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
GS + + L V KP S K S+ R M + + N +
Sbjct: 12876 SSGSKSAT-IKLKVLDKPGPPASVKINKMYSD-----RAMLSWEPPLEDGGSEITNYIVD 12929
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG-----FSTTTVKLD 453
TS +A+ IT SV + + +Y C A N+ G F+ + +
Sbjct: 12930 KRETSRPNWAQVSATVPITSCSVEKL--IEGHEYQFRIC-AENKYGVGDPVFTEPAIAKN 12986
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ--SWYRIRYRKVFDDSYKYEDVLPKH 511
P + ++N+T +T+ W P D G + Y + R+ ++ + P
Sbjct: 12987 PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPII 13046
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
GL++ T+Y F V AINK G K
Sbjct: 13047 ERTLKATGLQEGTEYEFRVTAINKAGPGK 13075
Score = 37.9 bits (84), Expect = 0.15
Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 10/128 (7%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKY-EDVLPKHATNFTVHGLEK 522
VT+ + S+V+L W P +DGG Y + ++ D + FTV L++
Sbjct: 18514 VTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKE 18573
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVIVYVSL 582
NT+Y F + AIN G + TL S V + E D+ K V++ S
Sbjct: 18574 NTEYNFRICAINSEGVG-------EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18626
Query: 583 TGAVLVLI 590
T + V I
Sbjct: 18627 TLRLFVTI 18634
Score = 37.9 bits (84), Expect = 0.15
Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 458 PDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHATNF 515
P VV +T T+ T TV+LEW P FDGG++ Y I K + + T +
Sbjct: 21759 PPTVVKVTDTSKT--TVSLEWSKPVFDGGMEIIGYIIEMCKTDLGDWHKVNAEACVKTRY 21816
Query: 516 TVHGLEKNTDYIFSVMAINKIGQ 538
TV L+ +Y F V AIN G+
Sbjct: 21817 TVTDLQAGEEYKFRVSAINGAGK 21839
Score = 37.9 bits (84), Expect = 0.15
Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 41/379 (10%)
Query: 184 ISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT--RHDAGIYTC 240
+S + G P P I W + G + QS ++ S+G +T +T + D G+YTC
Sbjct: 24055 LSCQIVGRPLPDIK--WYRFGKELIQSR----KYKMSSDGRTHTLTVMTEEQEDEGVYTC 24108
Query: 241 EAVNSQGAAVAN----ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
A N G + + + + G + + L IG P+ A + W
Sbjct: 24109 IATNEVGEVETSSKLLLQATPQFHPGY-PLKEKYYGAVGSTLRLHVMYIGRPVPA--MTW 24165
Query: 297 ERKGYKI--DPKSVTFEPKNLTSYLIIRKA-KSENLGNFQCVVNNGIGSATKQDVMLIVK 353
G K+ + +++T E ++L+++ + + G ++ ++N G+ D +L V+
Sbjct: 24166 FH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTV---DAILDVE 24221
Query: 354 F--KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
KP+ T P +++ V K +W N V K AE+
Sbjct: 24222 IQDKPDKPTGPIVIEALLKNSAV----ISWKPPADDGGSWITNYV--VEKCEAKEGAEWQ 24275
Query: 412 -KNDHITYTSVLLINNVATSDYGSYECGARNELGF------STTTVKLDVTSAPDQVVSL 464
+ I+ T+ ++N + Y + A+N G S+ + P
Sbjct: 24276 LVSSAISVTTCRIVNLTENAGY-YFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKP 24334
Query: 465 TVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
T+T VT + + W P DGG + Y + R+ + + T F+V L +
Sbjct: 24335 TITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIE 24394
Query: 523 NTDYIFSVMAINKIGQSKY 541
+Y F V N G+S++
Sbjct: 24395 GLEYEFRVKCENLGGESEW 24413
Score = 37.5 bits (83), Expect = 0.19
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 5/126 (3%)
Query: 446 STTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYK 503
S + LD P + V L N+T TVTL+W P + GG + + Y + R + + +
Sbjct: 14851 SEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWL 14907
Query: 504 YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVS 563
+ FTV GL ++ Y F V+A N G + + A T V
Sbjct: 14908 KANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVD 14967
Query: 564 TEYVET 569
++ +T
Sbjct: 14968 VKFKDT 14973
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 12/125 (9%)
Query: 51 NPLATLTWFKNDKKIH------STTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEI 104
+P +TW+K+ +KI T +DK + +++I + TD+ A+Y A N E
Sbjct: 25219 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY-QLTINSVTTDDDAEYTVVARNKYGED 25277
Query: 105 PLFETVTLNVHFAPEAVKVRAEPDVLKPGIEAT---LICDS--ASSNPPATLSWWRDGIP 159
+T+ +H P +R L E +C S PP TL W +DG P
Sbjct: 25278 SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQP 25337
Query: 160 VQNAP 164
+ P
Sbjct: 25338 LSLGP 25342
Score = 37.1 bits (82), Expect = 0.26
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSL-----TVTNVTHSTVTLEWVPGF-D 483
SDY + A N G ++ D +A D + VT+ T S+ LEW P D
Sbjct: 9892 SDY-QFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKD 9950
Query: 484 GGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
GG + + Y + Y++ + ++ T V GL++ Y F V A+N G
Sbjct: 9951 GGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVSAVNIAG 10005
Score = 37.1 bits (82), Expect = 0.26
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Query: 466 VTNVTHSTVTLEWV-PGFDGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
V + T +++L W P +DGG + + K D Y+ T FTV L+
Sbjct: 22853 VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKM 22912
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGEL 559
Y F V A+N G S+Y + + E+ +L
Sbjct: 22913 GQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDL 22949
Score = 37.1 bits (82), Expect = 0.26
Identities = 55/254 (21%), Positives = 103/254 (40%), Gaps = 18/254 (7%)
Query: 296 WERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W G K+ + + VT E + L IR+ + G + + N G+ T + + +I+
Sbjct: 23275 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGT-TSETIKVIILD 23333
Query: 355 KPEMDTSPNFVKS--ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP--VNTSTKYFAEF 410
KP T P + A+++ P + + P + S
Sbjct: 23334 KPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST 23393
Query: 411 HKNDHITYTSVLLINNVATSDYG--SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
K +T + + AT+ +G SY ++E+ +++++ P +L + +
Sbjct: 23394 FKFTRLTEGNEYVFRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPETLQIFD 23445
Query: 469 VTHSTVTLEWVP-GFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDY 526
V+ +TL W P DGG Q + Y + ++V D + + +P T + GL + +Y
Sbjct: 23446 VSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEY 23505
Query: 527 IFSVMAINKIGQSK 540
V AIN G K
Sbjct: 23506 EHRVTAINARGSGK 23519
Score = 36.7 bits (81), Expect = 0.34
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 6/107 (5%)
Query: 438 GARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPG-FDGGLQ-SWYRIRYR 495
G + + D PD V + V N T +T+ W P +DGG + Y I
Sbjct: 8063 GGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKI 8122
Query: 496 KVFDDSYK--YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
++ +K E ++P +T GLE+ +Y F V A N G S+
Sbjct: 8123 AKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGISE 8167
Score = 36.7 bits (81), Expect = 0.34
Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V APD+ TV++VT +++T+ W P +DGG + Y + + +K + P
Sbjct: 9819 VPGAPDKP---TVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIK 9875
Query: 512 A----TNFTVHGLEKNTDYIFSVMAINKIG 537
A ++ V GL + +DY F V AIN G
Sbjct: 9876 AMTLGVSYKVTGLIEGSDYQFRVYAINAAG 9905
Score = 36.3 bits (80), Expect = 0.45
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 19/122 (15%)
Query: 137 TLICDSASSNPPATLS-WWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSI 195
T+IC P L +DG+ ++ DT N + I +PL P S
Sbjct: 13869 TIICKDEYEAPTIVLDPTIKDGLTIKAG----DTIVLNAISILGKPL---------PKS- 13914
Query: 196 TYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISV 255
+W+K G I S + S SML + TR DAG YT A N G V ++ V
Sbjct: 13915 --SWSKAGKDIRPSDITQITSTPTS--SMLTIKYATRKDAGEYTITATNPFGTKVEHVKV 13970
Query: 256 SV 257
+V
Sbjct: 13971 TV 13972
Score = 35.9 bits (79), Expect = 0.60
Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 22 SAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT---DKAVSA 78
+AP+I + +A G + K C P WFK ++I+ + K + K +S+
Sbjct: 4335 AAPVIKRKIEPLEVALGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4393
Query: 79 EISILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
+ T V D +Y C+A+N + T+T+ V
Sbjct: 4394 LEILRTQVVDC-GEYTCKASNEYGSVSCTATLTVTV 4428
Score = 35.9 bits (79), Expect = 0.60
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 465 TVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSY-KYEDVLPKHATNFTVHGLE 521
TV +V ++V L W P DGG + Y I K D + + + +P T + GL
Sbjct: 7494 TVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVP--TTQHLLPGLM 7551
Query: 522 KNTDYIFSVMAINKIGQSK 540
+ +Y F V A+NK G+S+
Sbjct: 7552 EGQEYSFRVRAVNKAGESE 7570
Score = 35.9 bits (79), Expect = 0.60
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 32 GTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHST--TKTTDKAVSAEISILTNVTDN 89
G T+ AG L IS G PL +W K K I + T+ T S+ ++I +
Sbjct: 13890 GLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKD 13949
Query: 90 QAQYRCEATNS-ATEIPLFETVTLNVHFAPEAVKV 123
+Y ATN T++ + L+V P V++
Sbjct: 13950 AGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEI 13984
Score = 35.9 bits (79), Expect = 0.60
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 11/100 (11%)
Query: 19 DPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT----KTTDK 74
DPP M Y + AG K+ G P+ T+ W K D+++ +T K+TD
Sbjct: 16042 DPPRISMDPKYKDTIVVHAGESFKVDA-DIYGKPIPTIQWIKGDQELSNTARLEIKSTDF 16100
Query: 75 AVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNV 114
A S +S+ V + Y +A N A E +VT+NV
Sbjct: 16101 ATS--LSVKDAVRVDSGNYILKAKNVAGE----RSVTVNV 16134
Score = 35.9 bits (79), Expect = 0.60
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK 510
D P + + + T S++TL W P +DGG + Y + R+ ++ + +
Sbjct: 20665 DPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGE 20724
Query: 511 -HATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
T + V L+ +Y F V A+N GQ +
Sbjct: 20725 VRTTEYVVSNLKPGVNYYFRVSAVNCAGQGE 20755
Score = 35.9 bits (79), Expect = 0.60
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 3/113 (2%)
Query: 16 SPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKI--HSTTKTTD 73
+P S P+I + TT+++ +V K A +T G P T W K+ K I K ++
Sbjct: 26347 APEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT-GEPRPTAIWTKDGKAITQGGKYKLSE 26405
Query: 74 KAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAE 126
+ I T + Y C NSA + +T+ EA KV +
Sbjct: 26406 DKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26458
Score = 35.5 bits (78), Expect = 0.79
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 8/137 (5%)
Query: 24 PMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTK---TTDKAVSAEI 80
PMI + T G + L T + W+ +K + S K D+ +
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKEV---NWYFENKLVPSDEKFKCLQDQNTYTLV 4299
Query: 81 SILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLIC 140
N D+Q +Y CEA N + + +T+ AP +K + EP + G A C
Sbjct: 4300 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP-VIKRKIEPLEVALGHLAKFTC 4358
Query: 141 DSASSNPPATLSWWRDG 157
+ S+ P W++ G
Sbjct: 4359 EIQSA-PNVRFQWFKAG 4374
Score = 35.5 bits (78), Expect = 0.79
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
VTN+T +V+L+W P +DGG + + Y + R++ D + + T F V L ++
Sbjct: 19196 VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 19255
Query: 524 TDYIFSVMAINKIGQSKYRPDDTKATTLTSSEV 556
Y F V A N S P ++ + +V
Sbjct: 19256 QRYEFRVFARN-AADSVSEPSESTGPIIVKDDV 19287
Score = 35.1 bits (77), Expect = 1.0
Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 13/116 (11%)
Query: 58 WFKNDKKIHSTTKTT--DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVH 115
WFKND+++H+T + D+ + I+ D+ +Q R EA ++E L + + +
Sbjct: 5464 WFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKL-TVLEGDPY 5522
Query: 116 FAPEAVKVRAEPDVLKPGIEATLICDSASSNPPATLSWWRDG---IPVQNAPIFDD 168
F K++ V K E L C+ + ++ P + W++DG P +NA I D
Sbjct: 5523 FTG---KLQDYTGVEKD--EVILQCEISKADAP--VKWFKDGKEIKPSKNAVIKTD 5571
Score = 35.1 bits (77), Expect = 1.0
Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 23 APMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTK--TTDKAVSAEI 80
AP I + T G +L+C G PL + W++ K++ + K + + +
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSC-QIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTL 24093
Query: 81 SILTNVTDNQAQYRCEATNSATEI 104
+++T +++ Y C ATN E+
Sbjct: 24094 TVMTEEQEDEGVYTCIATNEVGEV 24117
Score = 34.7 bits (76), Expect = 1.4
Identities = 66/301 (21%), Positives = 110/301 (36%), Gaps = 36/301 (11%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P IT W KD + + ++ T+++ DAG YT A G V+
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMS--DAGKYTVVA----GGNVST 3091
Query: 253 ISVSVH-YPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID---PKSV 308
+ V I+S+ + V + AV+ + + A W + G +I+ +
Sbjct: 3092 AKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAH---WYKDGIEINFQVQERH 3148
Query: 309 TFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM--DTSPNFVK 366
+ + + I + + + G + V S T + + P++ + P V+
Sbjct: 3149 KYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT---LYVNAPEPPQVLQELQPVTVQ 3205
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINN 426
S G+ R P P +W K L K+ +D YT LL+
Sbjct: 3206 S----GKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFL-----HDGQEYT--LLLIE 3254
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDV----TSAPDQ---VVSLTVTNVTHSTVTLEWV 479
D Y C A+N+ G +TT+ L V +PDQ V + TVT E
Sbjct: 3255 AFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQ 3314
Query: 480 P 480
P
Sbjct: 3315 P 3315
Score = 34.7 bits (76), Expect = 1.4
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 9/94 (9%)
Query: 451 KLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVL 508
K DV P +++T+T+V V+L W P +DGG + + Y I R S +++ +
Sbjct: 6690 KYDVPGPP---LNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRD--KTSIRWDTAM 6744
Query: 509 PKHATNF--TVHGLEKNTDYIFSVMAINKIGQSK 540
A + TV + + +Y F V A N+IG K
Sbjct: 6745 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGK 6778
Score = 34.7 bits (76), Expect = 1.4
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 455 TSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA 512
T P L V + + S+ L W+ P DGG + + Y + R+ D + E K
Sbjct: 22046 TEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDLW-VEAGHTKQL 22104
Query: 513 TNFTVHGLEKNTDYIFSVMAINKIGQSKYR 542
T FTV L + T+Y F V A N G S+ R
Sbjct: 22105 T-FTVERLVEKTEYEFRVKAKNDAGYSEPR 22133
Score = 34.7 bits (76), Expect = 1.4
Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 7/86 (8%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G+ R C P P+ TW + G L +TS + H+ Y S I++V SD
Sbjct: 26078 GESARFSCDTDGEPVPTVTWLRKGQVL--STSAR-----HQVTTTKYKSTFEISSVQASD 26130
Query: 432 YGSYECGARNELGFSTTTVKLDVTSA 457
G+Y N G L + A
Sbjct: 26131 EGNYSVVVENSEGKQEAEFTLTIQKA 26156
Score = 34.3 bits (75), Expect = 1.8
Identities = 25/121 (20%), Positives = 48/121 (39%), Gaps = 3/121 (2%)
Query: 420 SVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV 479
S L + + D+G Y N+ G + + V P ++ ++ ++V +W
Sbjct: 8267 SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWE 8326
Query: 480 PGFDGG---LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKI 536
P D G + ++ + K DS ++V L + +Y+F V A N+
Sbjct: 8327 PPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRF 8386
Query: 537 G 537
G
Sbjct: 8387 G 8387
Score = 34.3 bits (75), Expect = 1.8
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 453 DVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPK 510
D P + + + T +++TL W P +DGG + Y + K D +++ V P+
Sbjct: 17418 DPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA--DEEEWQIVTPQ 17475
Query: 511 ---HATNFTVHGLEKNTDYIFSVMAINKIG 537
T F + L ++ +Y V A+NK+G
Sbjct: 17476 TGLRVTRFEISKLTEHQEYKIRVCALNKVG 17505
Score = 33.9 bits (74), Expect = 2.4
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 7/97 (7%)
Query: 374 VGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYG 433
V + K P P+ W+K+G + KY K L I+ TSD G
Sbjct: 26371 VAKFAVKATGEPRPTAIWTKDGKA--ITQGGKYKLSEDKGGFF-----LEIHKTDTSDSG 26423
Query: 434 SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
Y C +N G +++ KL + + D T T
Sbjct: 26424 LYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKT 26460
Score = 33.5 bits (73), Expect = 3.2
Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 11/99 (11%)
Query: 360 TSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
T P V NV G+ L C P+P+ TW + + + +S + F
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQ--IESSIDFQITFQSG-- 950
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ L+I D G + C A NE G +T+ L V
Sbjct: 951 ---IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 33.5 bits (73), Expect = 3.2
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
C+ P P W K+GV P+ T +Y ++K T L+I+ D G Y
Sbjct: 1057 CQVGGNPKPHVYWKKSGV--PLTTGYRYKVSYNKQ---TGECKLVISMTFADDAGEYTIV 1111
Query: 439 ARNELGFSTTTVKL 452
RN+ G ++ + L
Sbjct: 1112 VRNKHGETSASASL 1125
Score = 33.5 bits (73), Expect = 3.2
Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 7/99 (7%)
Query: 449 TVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGF-DGGLQSWYRIRYRKVFD------DS 501
T D PD + L + +T +TV L W P DGG + I +D ++
Sbjct: 9506 TTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEA 9565
Query: 502 YKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
++ + FTV L + +Y F V A+N G SK
Sbjct: 9566 WRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSK 9604
Score = 33.5 bits (73), Expect = 3.2
Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 5/86 (5%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHA 512
V APDQ + VT VT + + W DGG + Y + R+ + P H
Sbjct: 10514 VPDAPDQPI---VTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHP 10570
Query: 513 -TNFTVHGLEKNTDYIFSVMAINKIG 537
T F V L + Y F V A N+IG
Sbjct: 10571 YTKFRVPDLLEGCQYEFRVSAENEIG 10596
Score = 33.5 bits (73), Expect = 3.2
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK--HATNFTVHGLE 521
VT +T +++T+ W P DGG S Y + R S + VL + T V GL
Sbjct: 20577 VTKITKNSMTVVWSRPIADGGSDISGYFLEKRD--KKSLGWFKVLKETIRDTRQKVTGLT 20634
Query: 522 KNTDYIFSVMAINKIGQSKY 541
+N+DY + V A+N GQ +
Sbjct: 20635 ENSDYQYRVCAVNAAGQGPF 20654
Score = 33.1 bits (72), Expect = 4.2
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 414 DHITYTSVLLINNVATSDY-GSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHS 472
D TYT L+I+ V T D+ G Y C A N+ G + T+ KL V V+ + +
Sbjct: 4292 DQNTYT--LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPL--- 4346
Query: 473 TVTLEWVPGFDGGLQSWYRIRYR 495
V L + F +QS +R++
Sbjct: 4347 EVALGHLAKFTCEIQSAPNVRFQ 4369
Score = 33.1 bits (72), Expect = 4.2
Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 466 VTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRK----VFDDSYKYEDVLPKHATNFTVHGL 520
VT+VT STV+L W P +DGG + I RK V D + + FTV L
Sbjct: 22450 VTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTAL 22509
Query: 521 EKNTDYIFSVMAINKIG 537
+ Y F V+A N G
Sbjct: 22510 SEGDTYEFRVLAKNAAG 22526
Score = 32.7 bits (71), Expect = 5.5
Identities = 57/249 (22%), Positives = 94/249 (37%), Gaps = 25/249 (10%)
Query: 218 IISEGS--MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPN 275
+I++G +L + T D G Y V GAA A ++V I ++
Sbjct: 6102 VIADGKKRVLVVKDATLQDMGTY----VVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQ 6157
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
++ V +C A KW R I D K+L L IR A ++ N+
Sbjct: 6158 QEVVFNCEVNTEGAKA---KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNV 6214
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVG-RLMCKCKSVPAPSFTWSK 393
+ N G K LIV+ + P +K + + CK + + W+K
Sbjct: 6215 SLTNHRGENVKSAANLIVEEEDLRIVEP--LKDIETMEKKSVTFWCKVNRLNV-TLKWTK 6271
Query: 394 NGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLD 453
NG ++P + Y + +K+ +L I + D G Y A G + +L
Sbjct: 6272 NGEEVPFDNRVSYRVDKYKH-------MLTIKDCGFPDEGEYIVTA----GQDKSVAELL 6320
Query: 454 VTSAPDQVV 462
+ AP + V
Sbjct: 6321 IIEAPTEFV 6329
Score = 32.3 bits (70), Expect = 7.3
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Query: 466 VTNVTHSTVTLEWVP-GFDGGLQS-WYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
VT+ + +T+ LEW P F+GG + Y + + V + + +TV + +
Sbjct: 8513 VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNKWSRCTEKMIKVRQYTVKEIREG 8572
Query: 524 TDYIFSVMAINKIGQSKYRPDDTKATTLTSSE 555
DY V A+N G+ P +T+ T+ +
Sbjct: 8573 ADYKLRVSAVNAAGEGP--PGETQPVTVAEPQ 8602
Score = 32.3 bits (70), Expect = 7.3
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 466 VTNVTHSTVTLEWV-PGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKN 523
V+NVT +T T+ W P DGG + + Y + R+ + P V GL++
Sbjct: 14083 VSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEG 14142
Query: 524 TDYIFSVMAINKIG 537
+ Y F V A N+ G
Sbjct: 14143 STYEFRVSAENRAG 14156
Score = 32.3 bits (70), Expect = 7.3
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 11/135 (8%)
Query: 130 LKPGIE---ATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNT--VGIENEPLII 184
LKPG+ + A P ++ + AP D + T + E + +
Sbjct: 20735 LKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQV 20794
Query: 185 SVRADGNPPSITYTWTKDGLPI-TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAV 243
+ G PP T TW KD + + + YS N S+L + ++TR+D G Y
Sbjct: 20795 LIPFKGRPPP-TVTWRKDEKNLGSDARYSIENT---DSSSLLTIPQVTRNDTGKYILTIE 20850
Query: 244 NSQGAAVAN-ISVSV 257
N G ++ +SV V
Sbjct: 20851 NGVGEPKSSTVSVKV 20865
Score = 31.9 bits (69), Expect = 9.7
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TWTK + + Q + + + + S + + R D G Y EAVN G A A
Sbjct: 7221 PEPKITWTKADMILKQDKRITIEN--VPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAV 7278
Query: 253 ISVSV 257
+ V+V
Sbjct: 7279 VEVNV 7283
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 79.4 bits (187), Expect = 5e-14
Identities = 82/316 (25%), Positives = 130/316 (41%), Gaps = 17/316 (5%)
Query: 264 KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTF---EPKNLTSYLI 320
K +N+ +A L C G+P +KW R+G +I + + E K LI
Sbjct: 2158 KEELRNLNVRYQSNATLVCKVTGHP--KPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 2215
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLI-VKFKPEMDTSPNFVKSASNV-GQVGRLM 378
I ++ +Q N GS + + + V K + + + + + G+V +
Sbjct: 2216 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIK 2275
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
P P TW K G L ++ + Y ++ +TS++ N V D G Y
Sbjct: 2276 IPFSGKPDPVITWQK-GQDL-IDNNGHYQVIVTRS----FTSLVFPNGVERKDAGFYVVC 2329
Query: 439 ARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
A+N G TV+LDV PD + V++ + +V L W P DGG + I K
Sbjct: 2330 AKNRFGIDQKTVELDVADVPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYI-VEKC 2388
Query: 498 FDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVG 557
+ ++ V T +TV L T Y F V+A NK G SK P + T+T +
Sbjct: 2389 ATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSK--PSEPSEPTITKEDKT 2446
Query: 558 ELSTVSTEYVETPDIS 573
E ET ++S
Sbjct: 2447 RAMNYDEEVDETREVS 2462
Score = 67.3 bits (157), Expect = 2e-10
Identities = 68/283 (24%), Positives = 107/283 (37%), Gaps = 14/283 (4%)
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK-IDPKSVTFEPKNLTSYLI 320
GI+ ++V E A LSC +G PL IKW R G + I + T L
Sbjct: 1761 GIRKEMKDVTTKLGEAAQLSCQIVGRPL--PDIKWYRFGKELIQSRKYKMSSDGRTHTLT 1818
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCK 380
+ + E+ G + C+ N +G +L+ P K VG RL
Sbjct: 1819 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVM 1878
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
P P+ TW +G KL N+ +H YT +++ N + G Y+
Sbjct: 1879 YIGRPVPAMTWF-HGQKLLQNSEN---ITIENTEH--YTHLVMKNVQRKTHAGKYKVQLS 1932
Query: 441 NELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFD 499
N G + +++ PD+ + + + ++ + W P D G SW + +
Sbjct: 1933 NVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG-GSWITNYVVEKCE 1991
Query: 500 DSYKYEDVLPKHATNFT---VHGLEKNTDYIFSVMAINKIGQS 539
E L A + T + L +N Y F V A N G S
Sbjct: 1992 AKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGIS 2034
Score = 61.3 bits (142), Expect = 1e-08
Identities = 60/226 (26%), Positives = 98/226 (43%), Gaps = 22/226 (9%)
Query: 356 PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P+++ + + K+ + G RLM P P TWSK G+ L D
Sbjct: 671 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAII---------D 721
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S+L+++ V D G Y A N+ G + TV + V P S+ V V+ +V
Sbjct: 722 TTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSV 781
Query: 475 TLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVM 531
T+ W +P DGG + Y + R+ ++K V K T + + GL + T + F V+
Sbjct: 782 TITWEIPTIDGGAPINNYIVEKREAAMRAFK--TVTTKCSKTLYRISGLVEGTMHYFRVL 839
Query: 532 AINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVI 577
N G + P +T L V E+ V + +E D++K +
Sbjct: 840 PENIYGIGE--PCETSDAVL----VSEVPLVPAK-LEVVDVTKSTV 878
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT------VKLDVTSAPDQVVSL 464
H IT T + V ++Y + A+N++G S T+ V D P Q L
Sbjct: 1606 HNKTQITTTMYTVTGLVPDAEY-QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGEL 1664
Query: 465 TVTNVTHSTVTLEWV-PGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
+ +++ +VTL+W P DGG + Y + YR+ D ++K + FT+ GL +
Sbjct: 1665 EILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLE 1724
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTK-ATTLTSSEV----GELSTVSTEYVETPDISKPVI 577
T+Y F V A N+ G S+ R T LTS E E+ V+T+ E +S ++
Sbjct: 1725 ATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIV 1784
Score = 54.4 bits (125), Expect = 2e-06
Identities = 93/400 (23%), Positives = 158/400 (39%), Gaps = 40/400 (10%)
Query: 20 PPSAP-MITGYVPGTTLAAGTVQKLACISTGGNPLAT-LTWFKNDKKIHSTTK-----TT 72
P SAP IT ++ A+ + KL C+ A +TW+K+ KK+ +
Sbjct: 3940 PVSAPPKITQFLKAE--ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSA 3997
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
D +I+ LT +Q +Y CE + T N+ F +A K E V K
Sbjct: 3998 DGTYELKINNLTE--SDQGEYVCEISGEGG------TSKTNLQFMGQAFKSIHEK-VSK- 4047
Query: 133 GIEATLICDSASSNPPATLSWW-RDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGN 191
I T D ++ T + P+ + P+ TV ++ +V+A G
Sbjct: 4048 -ISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKF-AVKATGE 4105
Query: 192 PPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV 250
P T WTKDG ITQ Y D+ G L + K D+G+YTC NS G+
Sbjct: 4106 PRP-TAIWTKDGKAITQGGKYKLSEDK---GGFFLEIHKTDTSDSGLYTCTVKNSAGSVS 4161
Query: 251 ANISVSV----HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPK 306
++ +++ A S + P + AV+ L +E IK + +
Sbjct: 4162 SSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS-EAKSQEKL 4220
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK 366
++ E + ++K+ + +L + +V+ I ++ + + + +
Sbjct: 4221 ALKEEASKVLISEEVKKSAATSLE--KSIVHEEITKTSQAS----EEVRTHAEIKAFSTQ 4274
Query: 367 SASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
+ N GQ RL+ K A W NGV+L + +Y
Sbjct: 4275 MSINEGQ--RLVLKANIAGATDVKWVLNGVELTNSEEYRY 4312
Score = 52.4 bits (120), Expect = 6e-06
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ- 487
SD G Y +N G +V + V +P LTV+ VT TL W +P DGG +
Sbjct: 340 SDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 399
Query: 488 SWYRIRYRKVFDDSYK-YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ Y + R+ ++ E P ++ V L KN +YIF V A+NK G
Sbjct: 400 THYIVERRETSRLNWVIVEGECP--TLSYVVTRLIKNNEYIFRVRAVNKYG 448
Score = 50.4 bits (115), Expect = 3e-05
Identities = 66/284 (23%), Positives = 116/284 (40%), Gaps = 22/284 (7%)
Query: 183 IISVRADGNPPSITYTWTKDGLPITQSS-YSSGNDRIISEGSMLNMTKLTRHDAGIYTCE 241
++ R PS W K+ LPI+ SS S R + L + + D+G YT +
Sbjct: 4378 VLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNVYS---LEIRNASVSDSGKYTIK 4434
Query: 242 AVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGY 301
A N +G A S+ V P ++ S+ VV + D L + + K E
Sbjct: 4435 AKNFRGQCSATASLMV-LPL-VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFS 4492
Query: 302 KIDPKSVT------FEPKNLTSYLIIRKAKSE-NLGNFQCVVN-NGIGSATKQDVMLIVK 353
S + F + S ++++ E + +F + N + S+T + + ++
Sbjct: 4493 SFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIR 4552
Query: 354 -FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
P+++ P+ + + + G+V + C P P TWS G K+ ++ E
Sbjct: 4553 GIPPKIEALPSDI--SIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE--N 4608
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
D +T L+I +V D G Y NE G + TV + + S
Sbjct: 4609 TDDLT---TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 4649
Score = 48.0 bits (109), Expect = 1e-04
Identities = 47/183 (25%), Positives = 71/183 (38%), Gaps = 11/183 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V RL K P P W+K G + +E H + L+I D
Sbjct: 1378 GGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIA-TSETH--------TELVIKEADRGD 1428
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSW 489
G+Y+ N+ G +K+ V +P+ L ++ +V + W P DGG
Sbjct: 1429 SGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 1488
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
I R+ + Y T+ V GL++N +Y F V A N+ G SK + T
Sbjct: 1489 GYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 1548
Query: 550 TLT 552
T
Sbjct: 1549 PKT 1551
Score = 46.8 bits (106), Expect = 3e-04
Identities = 39/115 (33%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Query: 345 KQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL-PVNTS 403
+ D M +++ PE T P + K+A VG+ R P P TW K+G K+ P +
Sbjct: 2906 RTDTMRLLERPPEF-TLPLYNKTAY-VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDND 2963
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
KY E K + L IN+V T D Y ARN+ G + KL VT P
Sbjct: 2964 KKYTFESDKGLY-----QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP 3013
Score = 46.0 bits (104), Expect = 6e-04
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V+ P L V +VT STVTL W P +DGG + + Y + K + + L
Sbjct: 858 VSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPT 917
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATT--LTSSEVGELSTVSTEYVET 569
TV L + Y+F + A N+ G S+ R T T L +LST+ + +
Sbjct: 918 VLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 977
Query: 570 PDISKPVIVYVSLTG 584
P +PV + + + G
Sbjct: 978 P-AGRPVELVIPIAG 991
Score = 46.0 bits (104), Expect = 6e-04
Identities = 40/172 (23%), Positives = 70/172 (40%), Gaps = 16/172 (9%)
Query: 293 HIKWERKGYKIDP----KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
H+ W + G KI P K TFE L I +++ + V N G + +
Sbjct: 2947 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 3006
Query: 349 MLIVKFKPEMDTS--PNFVKSASNVG-QVGRLMC---KCKSVPAPSFTWSKNGVKLPVNT 402
+ + P D++ P F + +N Q G+ +C + +P P+ W K+G L +
Sbjct: 3007 LTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGP 3066
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ + ++ + Y + L I + D G Y A N G ++ L V
Sbjct: 3067 NIEII-----HEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 3112
Score = 45.2 bits (102), Expect = 0.001
Identities = 52/217 (23%), Positives = 83/217 (38%), Gaps = 19/217 (8%)
Query: 243 VNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
V+ + + S V A IK+ S + N + VL G A +KW G +
Sbjct: 4248 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG----ATDVKWVLNGVE 4303
Query: 303 I-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS 361
+ + + + L I++A + G C+ G Q + + K E+ +
Sbjct: 4304 LTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSK---ELSDA 4360
Query: 362 PNFVKSAS----NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHIT 417
P F+ N GQ + P+P W KN LP++ S+ +N
Sbjct: 4361 PAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNN--LPISISSNVSISRSRN---V 4415
Query: 418 YTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
Y+ L I N + SD G Y A+N G + T L V
Sbjct: 4416 YS--LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 4450
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/161 (24%), Positives = 64/161 (39%), Gaps = 13/161 (8%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W G KL S + E H T + L I D G Y +N G
Sbjct: 993 PPPAASWFFAGSKL--RESERVTVETH-----TKVAKLTIRETTIRDTGEYTLELKNVTG 1045
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
+ T+K+ + P + + + +++T+ W P DGG S Y + R
Sbjct: 1046 TTLETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPG 1105
Query: 502 Y-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ + + + FT L + +Y+F V A N+ G Y
Sbjct: 1106 WLPVSESVTRSTFKFT--RLTEGNEYVFRVAATNRFGIGSY 1144
Score = 44.4 bits (100), Expect = 0.002
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I + + + DD T+ L + V G PP + TW+K G+ + + +
Sbjct: 668 IEIPDLELADDLKKTVTIRA-GASLRLMVSVSGRPPPVI-TWSKQGIDLASRAIIDTTES 725
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG 262
S+L + K+ R+DAG YT EA N G A + V V+ G
Sbjct: 726 Y----SLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG 766
Score = 40.3 bits (90), Expect = 0.028
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 9/90 (10%)
Query: 364 FVKSASNVGQVGRLMCKCKS--VPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
F+K+ ++ ++ +L C +S + A TW K+G KL N +F +FH + TY
Sbjct: 3950 FLKAEASK-EIAKLTCVVESSVLRAKEVTWYKDGKKLKENG---HF-QFHYSADGTYE-- 4002
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVK 451
L INN+ SD G Y C E G S T ++
Sbjct: 4003 LKINNLTESDQGEYVCEISGEGGTSKTNLQ 4032
Score = 38.7 bits (86), Expect = 0.084
Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 11/131 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAP 387
F+ N G + + + +K K +P K +V G+ +L C+ P P
Sbjct: 1730 FRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLP 1789
Query: 388 SFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFST 447
W + G +L S KY +D T+T L + D G Y C A NE+G
Sbjct: 1790 DIKWYRFGKELI--QSRKYKMS---SDGRTHT--LTVMTEEQEDEGVYTCIATNEVGEVE 1842
Query: 448 TTVKLDVTSAP 458
T+ KL + + P
Sbjct: 1843 TSSKLLLQATP 1853
Score = 37.9 bits (84), Expect = 0.15
Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 41/379 (10%)
Query: 184 ISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT--RHDAGIYTC 240
+S + G P P I W + G + QS ++ S+G +T +T + D G+YTC
Sbjct: 1779 LSCQIVGRPLPDIK--WYRFGKELIQSR----KYKMSSDGRTHTLTVMTEEQEDEGVYTC 1832
Query: 241 EAVNSQGAAVAN----ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
A N G + + + + G + + L IG P+ A + W
Sbjct: 1833 IATNEVGEVETSSKLLLQATPQFHPGY-PLKEKYYGAVGSTLRLHVMYIGRPVPA--MTW 1889
Query: 297 ERKGYKI--DPKSVTFEPKNLTSYLIIRKA-KSENLGNFQCVVNNGIGSATKQDVMLIVK 353
G K+ + +++T E ++L+++ + + G ++ ++N G+ D +L V+
Sbjct: 1890 FH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTV---DAILDVE 1945
Query: 354 F--KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
KP+ T P +++ V K +W N V K AE+
Sbjct: 1946 IQDKPDKPTGPIVIEALLKNSAV----ISWKPPADDGGSWITNYV--VEKCEAKEGAEWQ 1999
Query: 412 -KNDHITYTSVLLINNVATSDYGSYECGARNELGF------STTTVKLDVTSAPDQVVSL 464
+ I+ T+ ++N + Y + A+N G S+ + P
Sbjct: 2000 LVSSAISVTTCRIVNLTENAGY-YFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKP 2058
Query: 465 TVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
T+T VT + + W P DGG + Y + R+ + + T F+V L +
Sbjct: 2059 TITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIE 2118
Query: 523 NTDYIFSVMAINKIGQSKY 541
+Y F V N G+S++
Sbjct: 2119 GLEYEFRVKCENLGGESEW 2137
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 12/125 (9%)
Query: 51 NPLATLTWFKNDKKIH------STTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEI 104
+P +TW+K+ +KI T +DK + +++I + TD+ A+Y A N E
Sbjct: 2943 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY-QLTINSVTTDDDAEYTVVARNKYGED 3001
Query: 105 PLFETVTLNVHFAPEAVKVRAEPDVLKPGIEAT---LICDS--ASSNPPATLSWWRDGIP 159
+T+ +H P +R L E +C S PP TL W +DG P
Sbjct: 3002 SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQP 3061
Query: 160 VQNAP 164
+ P
Sbjct: 3062 LSLGP 3066
Score = 37.1 bits (82), Expect = 0.26
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Query: 466 VTNVTHSTVTLEWV-PGFDGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
V + T +++L W P +DGG + + K D Y+ T FTV L+
Sbjct: 577 VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKM 636
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGEL 559
Y F V A+N G S+Y + + E+ +L
Sbjct: 637 GQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDL 673
Score = 36.3 bits (80), Expect = 0.45
Identities = 55/254 (21%), Positives = 103/254 (40%), Gaps = 18/254 (7%)
Query: 296 WERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W G K+ + + VT E + L IR+ + G + + N G+ T + + +I+
Sbjct: 999 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGT-TLETIKVIILD 1057
Query: 355 KPEMDTSPNFVKS--ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP--VNTSTKYFAEF 410
KP T P + A+++ P + + P + S
Sbjct: 1058 KPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST 1117
Query: 411 HKNDHITYTSVLLINNVATSDYG--SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
K +T + + AT+ +G SY ++E+ +++++ P +L + +
Sbjct: 1118 FKFTRLTEGNEYVFRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPETLQIFD 1169
Query: 469 VTHSTVTLEWVP-GFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDY 526
V+ +TL W P DGG Q + Y + ++V D + + +P T + GL + +Y
Sbjct: 1170 VSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEY 1229
Query: 527 IFSVMAINKIGQSK 540
V AIN G K
Sbjct: 1230 EHRVTAINARGSGK 1243
Score = 35.9 bits (79), Expect = 0.60
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 3/113 (2%)
Query: 16 SPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKI--HSTTKTTD 73
+P S P+I + TT+++ +V K A +T G P T W K+ K I K ++
Sbjct: 4071 APEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT-GEPRPTAIWTKDGKAITQGGKYKLSE 4129
Query: 74 KAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAE 126
+ I T + Y C NSA + +T+ EA KV +
Sbjct: 4130 DKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 4182
Score = 35.1 bits (77), Expect = 1.0
Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 23 APMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTK--TTDKAVSAEI 80
AP I + T G +L+C G PL + W++ K++ + K + + +
Sbjct: 1759 APGIRKEMKDVTTKLGEAAQLSC-QIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTL 1817
Query: 81 SILTNVTDNQAQYRCEATNSATEI 104
+++T +++ Y C ATN E+
Sbjct: 1818 TVMTEEQEDEGVYTCIATNEVGEV 1841
Score = 34.3 bits (75), Expect = 1.8
Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 7/86 (8%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G+ R C P P+ TW + G L +TS + H+ Y S I++V SD
Sbjct: 3802 GESARFSCDTDGEPVPTVTWLRKGRVL--STSAR-----HQVTTTKYKSTFEISSVQASD 3854
Query: 432 YGSYECGARNELGFSTTTVKLDVTSA 457
G+Y N G L + A
Sbjct: 3855 EGNYSVVVENSEGKQEAEFTLTIQKA 3880
Score = 33.9 bits (74), Expect = 2.4
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 7/97 (7%)
Query: 374 VGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYG 433
V + K P P+ W+K+G + KY K L I+ TSD G
Sbjct: 4095 VAKFAVKATGEPRPTAIWTKDGKA--ITQGGKYKLSEDKGGFF-----LEIHKTDTSDSG 4147
Query: 434 SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
Y C +N G +++ KL + + D T T
Sbjct: 4148 LYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKT 4184
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 79.4 bits (187), Expect = 5e-14
Identities = 82/316 (25%), Positives = 130/316 (41%), Gaps = 17/316 (5%)
Query: 264 KSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTF---EPKNLTSYLI 320
K +N+ +A L C G+P +KW R+G +I + + E K LI
Sbjct: 2158 KEELRNLNVRYQSNATLVCKVTGHP--KPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 2215
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLI-VKFKPEMDTSPNFVKSASNV-GQVGRLM 378
I ++ +Q N GS + + + V K + + + + + G+V +
Sbjct: 2216 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIK 2275
Query: 379 CKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECG 438
P P TW K G L ++ + Y ++ +TS++ N V D G Y
Sbjct: 2276 IPFSGKPDPVITWQK-GQDL-IDNNGHYQVIVTRS----FTSLVFPNGVERKDAGFYVVC 2329
Query: 439 ARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWV-PGFDGGLQSWYRIRYRKV 497
A+N G TV+LDV PD + V++ + +V L W P DGG + I K
Sbjct: 2330 AKNRFGIDQKTVELDVADVPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYI-VEKC 2388
Query: 498 FDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVG 557
+ ++ V T +TV L T Y F V+A NK G SK P + T+T +
Sbjct: 2389 ATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSK--PSEPSEPTITKEDKT 2446
Query: 558 ELSTVSTEYVETPDIS 573
E ET ++S
Sbjct: 2447 RAMNYDEEVDETREVS 2462
Score = 67.3 bits (157), Expect = 2e-10
Identities = 68/283 (24%), Positives = 107/283 (37%), Gaps = 14/283 (4%)
Query: 262 GIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK-IDPKSVTFEPKNLTSYLI 320
GI+ ++V E A LSC +G PL IKW R G + I + T L
Sbjct: 1761 GIRKEMKDVTTKLGEAAQLSCQIVGRPL--PDIKWYRFGKELIQSRKYKMSSDGRTHTLT 1818
Query: 321 IRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCK 380
+ + E+ G + C+ N +G +L+ P K VG RL
Sbjct: 1819 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVM 1878
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
P P+ TW +G KL N+ +H YT +++ N + G Y+
Sbjct: 1879 YIGRPVPAMTWF-HGQKLLQNSEN---ITIENTEH--YTHLVMKNVQRKTHAGKYKVQLS 1932
Query: 441 NELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFD 499
N G + +++ PD+ + + + ++ + W P D G SW + +
Sbjct: 1933 NVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG-GSWITNYVVEKCE 1991
Query: 500 DSYKYEDVLPKHATNFT---VHGLEKNTDYIFSVMAINKIGQS 539
E L A + T + L +N Y F V A N G S
Sbjct: 1992 AKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGIS 2034
Score = 61.3 bits (142), Expect = 1e-08
Identities = 60/226 (26%), Positives = 98/226 (43%), Gaps = 22/226 (9%)
Query: 356 PEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKND 414
P+++ + + K+ + G RLM P P TWSK G+ L D
Sbjct: 671 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAII---------D 721
Query: 415 HITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTV 474
S+L+++ V D G Y A N+ G + TV + V P S+ V V+ +V
Sbjct: 722 TTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSV 781
Query: 475 TLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPK-HATNFTVHGLEKNTDYIFSVM 531
T+ W +P DGG + Y + R+ ++K V K T + + GL + T + F V+
Sbjct: 782 TITWEIPTIDGGAPINNYIVEKREAAMRAFK--TVTTKCSKTLYRISGLVEGTMHYFRVL 839
Query: 532 AINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDISKPVI 577
N G + P +T L V E+ V + +E D++K +
Sbjct: 840 PENIYGIGE--PCETSDAVL----VSEVPLVPAK-LEVVDVTKSTV 878
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT------VKLDVTSAPDQVVSL 464
H IT T + V ++Y + A+N++G S T+ V D P Q L
Sbjct: 1606 HNKTQITTTMYTVTGLVPDAEY-QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGEL 1664
Query: 465 TVTNVTHSTVTLEWV-PGFDGGLQSW-YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
+ +++ +VTL+W P DGG + Y + YR+ D ++K + FT+ GL +
Sbjct: 1665 EILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLE 1724
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTK-ATTLTSSEV----GELSTVSTEYVETPDISKPVI 577
T+Y F V A N+ G S+ R T LTS E E+ V+T+ E +S ++
Sbjct: 1725 ATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIV 1784
Score = 52.4 bits (120), Expect = 6e-06
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 430 SDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ- 487
SD G Y +N G +V + V +P LTV+ VT TL W +P DGG +
Sbjct: 340 SDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 399
Query: 488 SWYRIRYRKVFDDSYK-YEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIG 537
+ Y + R+ ++ E P ++ V L KN +YIF V A+NK G
Sbjct: 400 THYIVERRETSRLNWVIVEGECP--TLSYVVTRLIKNNEYIFRVRAVNKYG 448
Score = 48.0 bits (109), Expect = 1e-04
Identities = 47/183 (25%), Positives = 71/183 (38%), Gaps = 11/183 (6%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V RL K P P W+K G + +E H + L+I D
Sbjct: 1378 GGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIA-TSETH--------TELVIKEADRGD 1428
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQSW 489
G+Y+ N+ G +K+ V +P+ L ++ +V + W P DGG
Sbjct: 1429 SGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 1488
Query: 490 YRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
I R+ + Y T+ V GL++N +Y F V A N+ G SK + T
Sbjct: 1489 GYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 1548
Query: 550 TLT 552
T
Sbjct: 1549 PKT 1551
Score = 46.8 bits (106), Expect = 3e-04
Identities = 39/115 (33%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Query: 345 KQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL-PVNTS 403
+ D M +++ PE T P + K+A VG+ R P P TW K+G K+ P +
Sbjct: 2906 RTDTMRLLERPPEF-TLPLYNKTAY-VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDND 2963
Query: 404 TKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
KY E K + L IN+V T D Y ARN+ G + KL VT P
Sbjct: 2964 KKYTFESDKGLY-----QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP 3013
Score = 46.0 bits (104), Expect = 6e-04
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
Query: 454 VTSAPDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKH 511
V+ P L V +VT STVTL W P +DGG + + Y + K + + L
Sbjct: 858 VSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPT 917
Query: 512 ATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATT--LTSSEVGELSTVSTEYVET 569
TV L + Y+F + A N+ G S+ R T T L +LST+ + +
Sbjct: 918 VLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 977
Query: 570 PDISKPVIVYVSLTG 584
P +PV + + + G
Sbjct: 978 P-AGRPVELVIPIAG 991
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/161 (24%), Positives = 64/161 (39%), Gaps = 13/161 (8%)
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ +W G KL S + E H T + L I D G Y +N G
Sbjct: 993 PPPAASWFFAGSKL--RESERVTVETH-----TKVAKLTIRETTIRDTGEYTLELKNVTG 1045
Query: 445 FSTTTVKLDVTSAPDQVVS-LTVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDS 501
+ T+K+ + P + + + +++T+ W P DGG S Y + R
Sbjct: 1046 TTLETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPG 1105
Query: 502 Y-KYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKY 541
+ + + + FT L + +Y+F V A N+ G Y
Sbjct: 1106 WLPVSESVTRSTFKFT--RLTEGNEYVFRVAATNRFGIGSY 1144
Score = 44.4 bits (100), Expect = 0.002
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I + + + DD T+ L + V G PP + TW+K G+ + + +
Sbjct: 668 IEIPDLELADDLKKTVTIRA-GASLRLMVSVSGRPPPVI-TWSKQGIDLASRAIIDTTES 725
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG 262
S+L + K+ R+DAG YT EA N G A + V V+ G
Sbjct: 726 Y----SLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG 766
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/127 (23%), Positives = 53/127 (41%), Gaps = 10/127 (7%)
Query: 293 HIKWERKGYKIDP----KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDV 348
H+ W + G KI P K TFE L I +++ + V N G + +
Sbjct: 2947 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 3006
Query: 349 MLIVKFKPEMDTS--PNFVKSASNVG-QVGRLMC---KCKSVPAPSFTWSKNGVKLPVNT 402
+ + P D++ P F + +N Q G+ +C + +P P+ W K+G L +
Sbjct: 3007 LTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGP 3066
Query: 403 STKYFAE 409
+ + E
Sbjct: 3067 NIEIIHE 3073
Score = 38.7 bits (86), Expect = 0.084
Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 11/131 (8%)
Query: 332 FQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAP 387
F+ N G + + + +K K +P K +V G+ +L C+ P P
Sbjct: 1730 FRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLP 1789
Query: 388 SFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFST 447
W + G +L S KY +D T+T L + D G Y C A NE+G
Sbjct: 1790 DIKWYRFGKELI--QSRKYKMS---SDGRTHT--LTVMTEEQEDEGVYTCIATNEVGEVE 1842
Query: 448 TTVKLDVTSAP 458
T+ KL + + P
Sbjct: 1843 TSSKLLLQATP 1853
Score = 37.9 bits (84), Expect = 0.15
Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 41/379 (10%)
Query: 184 ISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLT--RHDAGIYTC 240
+S + G P P I W + G + QS ++ S+G +T +T + D G+YTC
Sbjct: 1779 LSCQIVGRPLPDIK--WYRFGKELIQSR----KYKMSSDGRTHTLTVMTEEQEDEGVYTC 1832
Query: 241 EAVNSQGAAVAN----ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKW 296
A N G + + + + G + + L IG P+ A + W
Sbjct: 1833 IATNEVGEVETSSKLLLQATPQFHPGY-PLKEKYYGAVGSTLRLHVMYIGRPVPA--MTW 1889
Query: 297 ERKGYKI--DPKSVTFEPKNLTSYLIIRKA-KSENLGNFQCVVNNGIGSATKQDVMLIVK 353
G K+ + +++T E ++L+++ + + G ++ ++N G+ D +L V+
Sbjct: 1890 FH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTV---DAILDVE 1945
Query: 354 F--KPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFH 411
KP+ T P +++ V K +W N V K AE+
Sbjct: 1946 IQDKPDKPTGPIVIEALLKNSAV----ISWKPPADDGGSWITNYV--VEKCEAKEGAEWQ 1999
Query: 412 -KNDHITYTSVLLINNVATSDYGSYECGARNELGF------STTTVKLDVTSAPDQVVSL 464
+ I+ T+ ++N + Y + A+N G S+ + P
Sbjct: 2000 LVSSAISVTTCRIVNLTENAGY-YFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKP 2058
Query: 465 TVTNVTHSTVTLEW-VPGFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
T+T VT + + W P DGG + Y + R+ + + T F+V L +
Sbjct: 2059 TITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIE 2118
Query: 523 NTDYIFSVMAINKIGQSKY 541
+Y F V N G+S++
Sbjct: 2119 GLEYEFRVKCENLGGESEW 2137
Score = 37.5 bits (83), Expect = 0.19
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 12/125 (9%)
Query: 51 NPLATLTWFKNDKKIH------STTKTTDKAVSAEISILTNVTDNQAQYRCEATNSATEI 104
+P +TW+K+ +KI T +DK + +++I + TD+ A+Y A N E
Sbjct: 2943 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY-QLTINSVTTDDDAEYTVVARNKYGED 3001
Query: 105 PLFETVTLNVHFAPEAVKVRAEPDVLKPGIEAT---LICDS--ASSNPPATLSWWRDGIP 159
+T+ +H P +R L E +C S PP TL W +DG P
Sbjct: 3002 SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQP 3061
Query: 160 VQNAP 164
+ P
Sbjct: 3062 LSLGP 3066
Score = 37.1 bits (82), Expect = 0.26
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Query: 466 VTNVTHSTVTLEWV-PGFDGG--LQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEK 522
V + T +++L W P +DGG + + K D Y+ T FTV L+
Sbjct: 577 VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKM 636
Query: 523 NTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGEL 559
Y F V A+N G S+Y + + E+ +L
Sbjct: 637 GQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDL 673
Score = 36.3 bits (80), Expect = 0.45
Identities = 55/254 (21%), Positives = 103/254 (40%), Gaps = 18/254 (7%)
Query: 296 WERKGYKI-DPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKF 354
W G K+ + + VT E + L IR+ + G + + N G+ T + + +I+
Sbjct: 999 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGT-TLETIKVIILD 1057
Query: 355 KPEMDTSPNFVKS--ASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP--VNTSTKYFAEF 410
KP T P + A+++ P + + P + S
Sbjct: 1058 KPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST 1117
Query: 411 HKNDHITYTSVLLINNVATSDYG--SYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
K +T + + AT+ +G SY ++E+ +++++ P +L + +
Sbjct: 1118 FKFTRLTEGNEYVFRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPETLQIFD 1169
Query: 469 VTHSTVTLEWVP-GFDGGLQ-SWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDY 526
V+ +TL W P DGG Q + Y + ++V D + + +P T + GL + +Y
Sbjct: 1170 VSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEY 1229
Query: 527 IFSVMAINKIGQSK 540
V AIN G K
Sbjct: 1230 EHRVTAINARGSGK 1243
Score = 35.1 bits (77), Expect = 1.0
Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 23 APMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTK--TTDKAVSAEI 80
AP I + T G +L+C G PL + W++ K++ + K + + +
Sbjct: 1759 APGIRKEMKDVTTKLGEAAQLSC-QIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTL 1817
Query: 81 SILTNVTDNQAQYRCEATNSATEI 104
+++T +++ Y C ATN E+
Sbjct: 1818 TVMTEEQEDEGVYTCIATNEVGEV 1841
>BX538014-1|CAD97961.1| 355|Homo sapiens hypothetical protein
protein.
Length = 355
Score = 79.4 bits (187), Expect = 5e-14
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 20/224 (8%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D G YTC + ++V P I +S ++ N + L+C A G P
Sbjct: 113 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKP--EPS 170
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W I P + FE YL I + G ++C N + + V ++V
Sbjct: 171 ISWRH----ISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVN 223
Query: 354 FKPEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
F P + +KS + G+ G + C+ VP P+F W K KL N +
Sbjct: 224 FAPTIQE----IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIIIQ--- 275
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ + S+L + NV +G+Y C A N+LG + ++ L+ S
Sbjct: 276 --NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 317
Score = 50.8 bits (116), Expect = 2e-05
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 194 SITYTWTKDGLPITQSSYS--SGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG-AAV 250
++T T G P S+ S + + G L++ +TR AG Y C A N V
Sbjct: 156 NVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 215
Query: 251 ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-EHIKWERKGYKIDPKSVT 309
+ V V++ I+ + V P ++ C G P A E K E+K + + +
Sbjct: 216 RKVKVVVNFAPTIQEIKSGTV-TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN-GQQGII 273
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
+ + S L + E+ GN+ CV N +G+
Sbjct: 274 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 306
>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
Length = 1496
Score = 79.4 bits (187), Expect = 5e-14
Identities = 101/405 (24%), Positives = 161/405 (39%), Gaps = 43/405 (10%)
Query: 170 TSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMT 228
T + G+ +A G+P P I W K G ++ + + GS+L +
Sbjct: 29 TPVDQTGVSGGVASFICQATGDPRPKIV--WNKKGKKVSNQRFEV-IEFDDGSGSVLRIQ 85
Query: 229 KL-TRHDAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVL 280
L T D IY C A N+ G + ++V P G ++ Q V A +
Sbjct: 86 PLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATM 145
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLI----IRKAKSENLGNFQCVV 336
C A GNP I W + +D + K L S I I +++ + G ++CV
Sbjct: 146 LCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVA 203
Query: 337 NNGIGSATKQDVMLIVKFKPEMD-TSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTW 391
N G+ L V+ E+ P F +N G + C P P W
Sbjct: 204 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 263
Query: 392 SKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVK 451
L ++D +VL +N+V S +Y C A + LG +
Sbjct: 264 MLGAEDLTP-----------EDDMPIGRNVLELNDVRQS--ANYTCVAMSTLGVIEAIAQ 310
Query: 452 LDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYR-KVFDDSYKYEDVLPK 510
+ V + P + VT T +++TL W G + S+Y I+++ K ++ YK D +
Sbjct: 311 ITVKALPKPPGTPVVTESTATSITLTWDSGNPEPV-SYYIIQHKPKNSEELYKEIDGVA- 368
Query: 511 HATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSE 555
T ++V GL +DY F V+A+N IG+ P T TS +
Sbjct: 369 -TTRYSVAGLSPYSDYEFRVVAVNNIGRG---PPSEPVLTQTSEQ 409
Score = 45.2 bits (102), Expect = 0.001
Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Query: 18 SDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVS 77
+D + P T T +G V C +TG +P + W K KK+ + +
Sbjct: 18 TDAETPPRFTRTPVDQTGVSGGVASFICQATG-DPRPKIVWNKKGKKVSNQRFEVIEFDD 76
Query: 78 AEISILT----NVTDNQAQYRCEATNSATEIPLFETVT-LNVHFAPEA---VKVRAEPDV 129
S+L ++A Y C A+N+ EI + +T L P + + + V
Sbjct: 77 GSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKV 136
Query: 130 LKPGIEATLICDSASSNPPATLSWWRDGIPVQNA 163
++ AT++C +AS NP ++W++D +PV +
Sbjct: 137 VERTRTATMLC-AASGNPDPEITWFKDFLPVDTS 169
Score = 36.3 bits (80), Expect = 0.45
Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 11/112 (9%)
Query: 348 VMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTS 403
++L + + +T P F ++ + G V +C+ P P W+K G K+ S
Sbjct: 10 LLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKV----S 65
Query: 404 TKYFAEFHKNDHITYTSVLLINNVAT-SDYGSYECGARNELGFSTTTVKLDV 454
+ F +D SVL I + T D YEC A N +G + + +L V
Sbjct: 66 NQRFEVIEFDD--GSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
>AL645724-1|CAI21858.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 79.4 bits (187), Expect = 5e-14
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 20/224 (8%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D G YTC + ++V P I +S ++ N + L+C A G P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKP--EPS 169
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W I P + FE YL I + G ++C N + + V ++V
Sbjct: 170 ISWRH----ISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVN 222
Query: 354 FKPEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
F P + +KS + G+ G + C+ VP P+F W K KL N +
Sbjct: 223 FAPTIQE----IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIIIQ--- 274
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ + S+L + NV +G+Y C A N+LG + ++ L+ S
Sbjct: 275 --NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 316
Score = 50.8 bits (116), Expect = 2e-05
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 194 SITYTWTKDGLPITQSSYS--SGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG-AAV 250
++T T G P S+ S + + G L++ +TR AG Y C A N V
Sbjct: 155 NVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
Query: 251 ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-EHIKWERKGYKIDPKSVT 309
+ V V++ I+ + V P ++ C G P A E K E+K + + +
Sbjct: 215 RKVKVVVNFAPTIQEIKSGTV-TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN-GQQGII 272
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
+ + S L + E+ GN+ CV N +G+
Sbjct: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
>AL627317-1|CAH72391.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 79.4 bits (187), Expect = 5e-14
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 20/224 (8%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D G YTC + ++V P I +S ++ N + L+C A G P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKP--EPS 169
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W I P + FE YL I + G ++C N + + V ++V
Sbjct: 170 ISWRH----ISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVN 222
Query: 354 FKPEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
F P + +KS + G+ G + C+ VP P+F W K KL N +
Sbjct: 223 FAPTIQE----IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIIIQ--- 274
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ + S+L + NV +G+Y C A N+LG + ++ L+ S
Sbjct: 275 --NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 316
Score = 50.8 bits (116), Expect = 2e-05
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 194 SITYTWTKDGLPITQSSYS--SGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG-AAV 250
++T T G P S+ S + + G L++ +TR AG Y C A N V
Sbjct: 155 NVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
Query: 251 ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-EHIKWERKGYKIDPKSVT 309
+ V V++ I+ + V P ++ C G P A E K E+K + + +
Sbjct: 215 RKVKVVVNFAPTIQEIKSGTV-TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN-GQQGII 272
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
+ + S L + E+ GN+ CV N +G+
Sbjct: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
>AL359821-1|CAH70913.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 79.4 bits (187), Expect = 5e-14
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 20/224 (8%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D G YTC + ++V P I +S ++ N + L+C A G P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKP--EPS 169
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W I P + FE YL I + G ++C N + + V ++V
Sbjct: 170 ISWRH----ISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVN 222
Query: 354 FKPEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
F P + +KS + G+ G + C+ VP P+F W K KL N +
Sbjct: 223 FAPTIQE----IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIIIQ--- 274
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ + S+L + NV +G+Y C A N+LG + ++ L+ S
Sbjct: 275 --NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 316
Score = 50.8 bits (116), Expect = 2e-05
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 194 SITYTWTKDGLPITQSSYS--SGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG-AAV 250
++T T G P S+ S + + G L++ +TR AG Y C A N V
Sbjct: 155 NVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
Query: 251 ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-EHIKWERKGYKIDPKSVT 309
+ V V++ I+ + V P ++ C G P A E K E+K + + +
Sbjct: 215 RKVKVVVNFAPTIQEIKSGTV-TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN-GQQGII 272
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
+ + S L + E+ GN+ CV N +G+
Sbjct: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
>AL356600-1|CAI23492.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 79.4 bits (187), Expect = 5e-14
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 20/224 (8%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D G YTC + ++V P I +S ++ N + L+C A G P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKP--EPS 169
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W I P + FE YL I + G ++C N + + V ++V
Sbjct: 170 ISWRH----ISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVN 222
Query: 354 FKPEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
F P + +KS + G+ G + C+ VP P+F W K KL N +
Sbjct: 223 FAPTIQE----IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIIIQ--- 274
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ + S+L + NV +G+Y C A N+LG + ++ L+ S
Sbjct: 275 --NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 316
Score = 50.8 bits (116), Expect = 2e-05
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 194 SITYTWTKDGLPITQSSYS--SGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG-AAV 250
++T T G P S+ S + + G L++ +TR AG Y C A N V
Sbjct: 155 NVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
Query: 251 ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-EHIKWERKGYKIDPKSVT 309
+ V V++ I+ + V P ++ C G P A E K E+K + + +
Sbjct: 215 RKVKVVVNFAPTIQEIKSGTV-TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN-GQQGII 272
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
+ + S L + E+ GN+ CV N +G+
Sbjct: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
>AL354949-1|CAI16869.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 79.4 bits (187), Expect = 5e-14
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 20/224 (8%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D G YTC + ++V P I +S ++ N + L+C A G P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKP--EPS 169
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W I P + FE YL I + G ++C N + + V ++V
Sbjct: 170 ISWRH----ISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVN 222
Query: 354 FKPEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
F P + +KS + G+ G + C+ VP P+F W K KL N +
Sbjct: 223 FAPTIQE----IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIIIQ--- 274
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ + S+L + NV +G+Y C A N+LG + ++ L+ S
Sbjct: 275 --NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 316
Score = 50.8 bits (116), Expect = 2e-05
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 194 SITYTWTKDGLPITQSSYS--SGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG-AAV 250
++T T G P S+ S + + G L++ +TR AG Y C A N V
Sbjct: 155 NVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
Query: 251 ANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-EHIKWERKGYKIDPKSVT 309
+ V V++ I+ + V P ++ C G P A E K E+K + + +
Sbjct: 215 RKVKVVVNFAPTIQEIKSGTV-TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN-GQQGII 272
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
+ + S L + E+ GN+ CV N +G+
Sbjct: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
>AK092307-1|BAC03858.1| 354|Homo sapiens protein ( Homo sapiens
cDNA FLJ34988 fis, clone OCBBF2011021, highly similar to
KILON PROTEIN PRECURSOR. ).
Length = 354
Score = 79.4 bits (187), Expect = 5e-14
Identities = 58/224 (25%), Positives = 93/224 (41%), Gaps = 20/224 (8%)
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
D G YTC + ++V P I +S ++ N + L+C A G P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKP--EPF 169
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
I W I P + FE YL I + G ++C N + + V ++V
Sbjct: 170 ISWRH----ISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVN 222
Query: 354 FKPEMDTSPNFVKSAS-NVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHK 412
F P + +KS + G+ G + C+ VP P+F W K KL N +
Sbjct: 223 FAPTIQE----IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIIIQ--- 274
Query: 413 NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
+ + S+L + NV +G+Y C A N+LG + ++ L+ S
Sbjct: 275 --NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 316
Score = 50.8 bits (116), Expect = 2e-05
Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 4/156 (2%)
Query: 189 DGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQG- 247
+G ++T T P + S + + G L++ +TR AG Y C A N
Sbjct: 152 EGTNVTLTCLATGKPEPFISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
Query: 248 AAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA-EHIKWERKGYKIDPK 306
V + V V++ I+ + V P ++ C G P A E K E+K + +
Sbjct: 212 PDVRKVKVVVNFAPTIQEIKSGTV-TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN-GQQ 269
Query: 307 SVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
+ + + S L + E+ GN+ CV N +G+
Sbjct: 270 GIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 79.4 bits (187), Expect = 5e-14
Identities = 106/425 (24%), Positives = 169/425 (39%), Gaps = 42/425 (9%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGND 216
+ V+ AP + T N V E + RA+GNP P I+ W +G+PI + + +
Sbjct: 350 VRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNPKPRIS--WLTNGVPI-EIAPDDPSR 405
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSV--HYPAGIKSVSQNVVANP 274
+I +G + + + + +Y C A N G +AN V+V P + +
Sbjct: 406 KI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIA 463
Query: 275 NEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC 334
N A+L C G+PL I+W KG K + L I A+ ++ G + C
Sbjct: 464 NRPALLDCAFFGSPLPT--IQWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 520
Query: 335 VVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT--WS 392
V N +G A K +V L +K + P + + G + CK K S T W
Sbjct: 521 VARNKLGMA-KNEVHLEIKDPTWIVKQPEY--AVVQRGSMVSFECKVKHDHTLSLTVLWL 577
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
K+ +LP S + F DH L++ +V+ D G+Y C A L + + L
Sbjct: 578 KDNRELP---SDERFTV--DKDH------LVVADVSDDDSGTYTCVANTTLDSVSASAVL 626
Query: 453 DVTS----------APDQVVSLTVTNVTHSTVTLEWVPGFDGGLQ-SWYRIRYRKVFDDS 501
V + P+ + L +T+ +V L W PG D + Y
Sbjct: 627 SVVAPTPTPAPVYDVPNPPLDLELTDQLDKSVQLSWTPGDDNNSPITTIHDEYEDAMHKP 686
Query: 502 YKYEDVLPKHATNFTVH-GLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELS 560
+ T T L +Y F VMA+N IG+S P + LT + + +
Sbjct: 687 GLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKS--LPSEASEQYLTKASEPDKN 744
Query: 561 TVSTE 565
+ E
Sbjct: 745 PTAVE 749
Score = 71.3 bits (167), Expect = 1e-11
Identities = 101/427 (23%), Positives = 163/427 (38%), Gaps = 46/427 (10%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILTNVT--DNQA 91
TL +G L C G P + W N + ++ + ++ ++ +NV D +
Sbjct: 151 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDL-YFSNVLPEDTRE 209
Query: 92 QYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLICDSASSN--PPA 149
Y C A + T+ T+ + + + V D + + T + SS PP
Sbjct: 210 DYICYARFNHTQ-----TIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPT 264
Query: 150 TLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDG-LPITQ 208
L+ P NA N + L + A+G P I Y +DG LP +
Sbjct: 265 FLT------PEGNAS--------NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNR 310
Query: 209 SSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQ 268
+ Y + L + ++ D+G Y C A N+ GA ISV V + Q
Sbjct: 311 TVYKNFE-------KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQ 363
Query: 269 NVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
N+V +P ED L C A GNP I W G I+ K +I + +
Sbjct: 364 NLVLSPGEDGTLICRANGNP--KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 421
Query: 329 LGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
+QC +N G + ++ P + T N + + L C P P+
Sbjct: 422 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVI-ANRPALLDCAFFGSPLPT 480
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD-YGSYECGARNELGFST 447
W K G K + H++ ++ + + L VA D G+Y C ARN+LG +
Sbjct: 481 IQWFK-GAK---------GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAK 530
Query: 448 TTVKLDV 454
V L++
Sbjct: 531 NEVHLEI 537
Score = 67.7 bits (158), Expect = 2e-10
Identities = 69/266 (25%), Positives = 114/266 (42%), Gaps = 21/266 (7%)
Query: 279 VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
VLS I L I W ++ + PK+ T KN L I + GN+QC+ N
Sbjct: 282 VLSLECIAEGLPTPIIYWAKEDGML-PKNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKN 339
Query: 339 GIGSATKQDVMLIVKFKPEMDTSP-NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVK 397
+G A + + VK P T+P N V S G+ G L+C+ P P +W NGV
Sbjct: 340 ALG-AIHHTISVRVKAAPYWITAPQNLVLSP---GEDGTLICRANGNPKPRISWLTNGVP 395
Query: 398 LPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
+ + K D T ++ +NV Y+C A NE G+ ++V +
Sbjct: 396 IEIAPDDPS----RKIDGDT----IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 447
Query: 458 PDQVV--SLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHAT-N 514
P +++ + T+ V + L F L + I++ K S +ED+ H
Sbjct: 448 PPRILTPANTLYQVIANRPALLDCAFFGSPLPT---IQWFKGAKGSALHEDIYVLHENGT 504
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
+ +K++ ++ +A NK+G +K
Sbjct: 505 LEIPVAQKDSTGTYTCVARNKLGMAK 530
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 10/87 (11%)
Query: 372 GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSD 431
G V L C + +P P W+K LP N + +KN + L I +V+ +D
Sbjct: 280 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTV------YKN----FEKTLQIIHVSEAD 329
Query: 432 YGSYECGARNELGFSTTTVKLDVTSAP 458
G+Y+C A+N LG T+ + V +AP
Sbjct: 330 SGNYQCIAKNALGAIHHTISVRVKAAP 356
Score = 39.5 bits (88), Expect = 0.048
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 257 VHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKG--YKIDPKS-VTFEPK 313
V P + ++ + +P E+ V+ C A G P W R G + ID VT +P
Sbjct: 38 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKP--PPSFSWTRNGTHFDIDKDPLVTMKPG 95
Query: 314 NLTSYL-IIRKAKSENL-GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV 371
T + I+ + K+E G +QC N G+A ++++ P + T
Sbjct: 96 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP-LWTKEKLEPITLQS 154
Query: 372 GQVGRLMCKCK-SVPAPSFTWSKNGV-KLP 399
GQ L C+ +P P W N +LP
Sbjct: 155 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLP 184
Score = 36.7 bits (81), Expect = 0.34
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
+ C+ K P PSF+W++NG ++ K T ++ A + G Y+
Sbjct: 61 IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM---KPGTGTLIINIMSEGKAETYEGVYQ 117
Query: 437 CGARNELG 444
C ARNE G
Sbjct: 118 CTARNERG 125
Score = 35.1 bits (77), Expect = 1.0
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGL-------PITQSSYSSGN--DRIISEGSMLNMTKL 230
E ++I A G PP +++WT++G P+ +G I+SEG K
Sbjct: 57 ENIVIQCEAKGKPPP-SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG------KA 109
Query: 231 TRHDAGIYTCEAVNSQGAAVANISV--SVHYPAGIKSVSQNVVANPNEDAVLSC-TAIGN 287
++ G+Y C A N +GAAV+N V P K + + + VL C IG
Sbjct: 110 ETYE-GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 168
Query: 288 P 288
P
Sbjct: 169 P 169
Score = 33.1 bits (72), Expect = 4.2
Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 458 PDQVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDV----LPKHA 512
P SL + N T ++TLEW P G+ + Y ++Y+ + +++++ + +P +
Sbjct: 947 PSVPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPI-NNTHELGPLVDLKIPANK 1005
Query: 513 TNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKAT 549
T +T+ L T Y F A G ++ T
Sbjct: 1006 TRWTLKNLNFTTRYKFYFYAQTSAGSGSQITEEAVTT 1042
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 79.0 bits (186), Expect = 6e-14
Identities = 95/385 (24%), Positives = 159/385 (41%), Gaps = 34/385 (8%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P TW +G+P+ + + I G+++ ++ + D + CEA N G +AN
Sbjct: 355 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALI-LSNVQPSDTMVTQCEARNRHGLLLAN 411
Query: 253 ISVSV-HYPAGIKSV-SQNVVANPNEDAVLSCTAIGNPLLAEHIKW-ERKGYKIDPKSVT 309
+ V PA I + +Q +A A L C A G P+ + ++W + G +
Sbjct: 412 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF 469
Query: 310 FEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS 369
F N T L IR ++ + G + C+ N + T +M +K + +
Sbjct: 470 FPYANGT--LGIRDLQANDTGRYFCLAANDQNNVT---IMANLKVTDATQITQGPRSTIE 524
Query: 370 NVGQVGRLMCKCKSVPA--PSFTWSKNGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINN 426
G C+ P+ PS TW +G L + S KYF E + L+I++
Sbjct: 525 KKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---------LVIHS 575
Query: 427 VATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN---VTHSTVTLEWVPGFD 483
+ SD G+Y C A EL + +L V +P V L +++ +T S V + W P D
Sbjct: 576 LDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAED 635
Query: 484 GGLQ-SWYRIRY--RKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y I + +++ + +P + T+ T+ L Y F V AINK G +
Sbjct: 636 HNAPIEKYDIEFEDKEMAPGKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGE 694
Query: 541 YRPDDTKATTLTSSEVGELSTVSTE 565
P T +T E + V +
Sbjct: 695 --PSPVSETVVTPEAAPEKNPVDVK 717
Score = 72.1 bits (169), Expect = 7e-12
Identities = 79/326 (24%), Positives = 126/326 (38%), Gaps = 23/326 (7%)
Query: 165 IFDDTTSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGS 223
+F +S + V ++ +PL++ A+G P P+I + +P +++Y + N
Sbjct: 238 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRATYQNHN-------K 290
Query: 224 MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + K+ D G Y C A NS G+A V+V Q+ + P E A L C
Sbjct: 291 TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQ 350
Query: 284 AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSA 343
G P + W G ++ + + + LI+ + + QC N G
Sbjct: 351 VQGRP--QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 408
Query: 344 TKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW-SKNGVKLPVNT 402
+ +V+ ++ T+ N A G L+CK P PS W ++G V
Sbjct: 409 LANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT--TVLQ 465
Query: 403 STKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVV 462
++F + N L I ++ +D G Y C A N+ T L VT A
Sbjct: 466 DERFFP--YAN------GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVTDATQITQ 517
Query: 463 SLTVT-NVTHSTVTLEWVPGFDGGLQ 487
T S VT FD LQ
Sbjct: 518 GPRSTIEKKGSRVTFTCQASFDPSLQ 543
Score = 42.7 bits (96), Expect = 0.005
Identities = 71/314 (22%), Positives = 120/314 (38%), Gaps = 34/314 (10%)
Query: 164 PIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPI-TQSSYSSGNDRIISEG 222
P+ + + V + + + A G P + + WT+DG+ + + G
Sbjct: 30 PVITEQSPRRLVVFPTDDISLKCEASGKP-EVQFRWTRDGVHFKPKEELGVTVYQSPHSG 88
Query: 223 SML---NMTKLTRHDAGIYTCEAVNSQGAAVAN-ISVSVH-YPAGIKSVSQNVVANPNED 277
S N + + GIY C A N G A+++ I + P K + V E
Sbjct: 89 SFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGES 148
Query: 278 AVLSCT--AIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
VL C PL + + K D + + NL ++ S+N ++ C
Sbjct: 149 VVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVL---TSDNHSDYICH 205
Query: 336 VNNGIGSAT---KQDVMLIVKFKPEM-DTSPNFV---KSASNV----GQVGRLMCKCKSV 384
+ G+ T K+ + L VK M D P + S+S++ GQ L C +
Sbjct: 206 AHFP-GTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGF 264
Query: 385 PAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELG 444
P P+ W + +P + +T ++N + L + V D G Y C A N LG
Sbjct: 265 PTPTIKWLRPSGPMPADRAT------YQN----HNKTLQLLKVGEEDDGEYRCLAENSLG 314
Query: 445 FSTTTVKLDVTSAP 458
+ + V +AP
Sbjct: 315 SARHAYYVTVEAAP 328
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 78.6 bits (185), Expect = 9e-14
Identities = 82/299 (27%), Positives = 128/299 (42%), Gaps = 23/299 (7%)
Query: 169 TTSYNTVGIENEP-LIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLN 226
T S TV + E + A G P P +T+T G +T ++ + ++ G+++
Sbjct: 1857 TKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFE-VLKNGTLV- 1914
Query: 227 MTKLTRHDAGIYTCEAVNSQGA--AVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTA 284
+ K+ D G Y C A N G V +SV+V P + S Q+V + + C A
Sbjct: 1915 IRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAMECLA 1974
Query: 285 IGNPLLAEHIKW---ERKGYK-IDP--KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN 338
G P A I W +R+ ++ + P +T +N T L I++A + G ++CV +N
Sbjct: 1975 KGTP--APQISWIFPDRRVWQTVSPVESRITLH-ENRT--LSIKEASFSDRGVYKCVASN 2029
Query: 339 GIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
G A + L V P + + G + C K+ P PS W L
Sbjct: 2030 AAG-ADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWV-----L 2083
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSA 457
T + H N + L I N+A D G YEC A N +G + TV+L+V A
Sbjct: 2084 GDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRA 2142
Score = 71.7 bits (168), Expect = 1e-11
Identities = 74/279 (26%), Positives = 118/279 (42%), Gaps = 22/279 (7%)
Query: 188 ADGNP-PSITYTWTKDGL--PITQSSYSSGNDR--IISEGSMLNMTKLTRHDAGIYTCEA 242
A G P P I+++ L QS S G + ++ L ++ + G YTC A
Sbjct: 2267 ATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFA 2326
Query: 243 VNSQGAAVANISVSV-HYPAGIKSVSQNVVANPNEDAV-LSCTAIGNPLLAEHIKWERKG 300
N G + V V PA I++ + V P D V ++C A G P+ + W
Sbjct: 2327 ENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPM--PKVTWLSPT 2384
Query: 301 YKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDT 360
K+ P S L+I+KA+ + GN+ C+V N G K + + P+++
Sbjct: 2385 NKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKING 2444
Query: 361 SPNFVKSASNVGQVGR---LMCKCKSVPAPSFTWS-KNGVKLPVNTSTKYFAEFHKNDHI 416
+PN + + + G + CK + +P P W+ GV LP A ++ N
Sbjct: 2445 NPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLP--------APYYGNRIT 2496
Query: 417 TY-TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
+ L I ++ SD C ARNE G + V+L V
Sbjct: 2497 VHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLIVQLTV 2535
Score = 66.5 bits (155), Expect = 4e-10
Identities = 62/253 (24%), Positives = 103/253 (40%), Gaps = 21/253 (8%)
Query: 219 ISEGSMLNMTKLTRHDAGIYTCEAVNSQGA--AVANISVSVHYPAGIKSVSQNVVANPNE 276
+ E L++ + + D G+Y C A N+ GA + V+ P + +N+ P
Sbjct: 2004 LHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGL 2063
Query: 277 DAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSY----LIIRKAKSENLGN 331
+ CTA PL + ++W G +I P F NL + L IR ++ G
Sbjct: 2064 SIHIHCTAKAAPLPS--VRWVLGDGTQIRPSQ--FLHGNLFVFPNGTLYIRNLAPKDSGR 2119
Query: 332 FQCVVNNGIGSATKQDVMLIVKFKPEM---DTSPNFVKSASNVGQVGRLMCKCKSVPAPS 388
++CV N +GSA + + + + TSP ++ G +L C P P
Sbjct: 2120 YECVAANLVGSARRTVQLNVQRAAANARITGTSPR--RTDVRYGGTLKLDCSASGDPWPR 2177
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTT 448
W +LP F + L++ +V D G Y C ARN++G
Sbjct: 2178 ILW-----RLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYV 2232
Query: 449 TVKLDVTSAPDQV 461
+K+DV P ++
Sbjct: 2233 VLKVDVVMKPAKI 2245
Score = 63.7 bits (148), Expect = 3e-09
Identities = 74/331 (22%), Positives = 127/331 (38%), Gaps = 17/331 (5%)
Query: 130 LKPGIEATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRAD 189
L+ L+C + + A L + PIF D S + + ++ A
Sbjct: 2508 LRKSDSVQLVCMARNEGGEARLIVQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAA 2567
Query: 190 GNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGA 248
G P PS+ W QS ++G ML+++ L+ DAG Y C A N+ G
Sbjct: 2568 GTPTPSLV--WVLPNGTDLQSGQQLQRFYHKADG-MLHISGLSSVDAGAYRCVARNAAGH 2624
Query: 249 AVANISVSVHYPAGIKSVSQNVVANPNEDAV-LSCTAIGNPLLAEHIKWER-KGYKID-P 305
+S+ V N+V+ N + + L CT G W G ++ P
Sbjct: 2625 TERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAG--QGRFSWTLPNGMHLEGP 2682
Query: 306 KSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFV 365
+++ L +R+A + G + C + G + ++++ + P + + P V
Sbjct: 2683 QTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPV 2742
Query: 366 KSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTK--YFAEFHKNDHITYTSVLL 423
+ G +L C +P TW +LP + K A + N + L
Sbjct: 2743 -IYTRPGNTVKLNCMAMGIPKADITW-----ELPDKSHLKAGVQARLYGNRFLHPQGSLT 2796
Query: 424 INNVATSDYGSYECGARNELGFSTTTVKLDV 454
I + D G Y+C A+N LG + T + V
Sbjct: 2797 IQHATQRDAGFYKCMAKNILGSDSKTTYIHV 2827
Score = 58.0 bits (134), Expect = 1e-07
Identities = 59/284 (20%), Positives = 113/284 (39%), Gaps = 19/284 (6%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS+ + DG I S + GN + G+ L + L D+G Y C A N G+A
Sbjct: 2077 PSVRWV-LGDGTQIRPSQFLHGNLFVFPNGT-LYIRNLAPKDSGRYECVAANLVGSARRT 2134
Query: 253 ISVSVHYPAGIKSVS----QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSV 308
+ ++V A ++ + L C+A G+P I W ++
Sbjct: 2135 VQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPW--PRILWRLPSKRMIDALF 2192
Query: 309 TFEPKN---LTSYLIIRKAKSENLGNFQCVVNNGIGS---ATKQDVMLIVKFKPEMDTSP 362
+F+ + L+++ ++ G++ CV N +G K DV++ + +
Sbjct: 2193 SFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEEND 2252
Query: 363 NFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTS-V 421
+ V ++ ++ C +P P +WS L + + ++ + +
Sbjct: 2253 HKVFYGGDL----KVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGT 2308
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLT 465
L N V + G Y C A N++G V++ V +AP + + T
Sbjct: 2309 LYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKT 2352
Score = 58.0 bits (134), Expect = 1e-07
Identities = 82/350 (23%), Positives = 137/350 (39%), Gaps = 35/350 (10%)
Query: 158 IPVQNAPIFDDTTSYNTVGIE-NEPLIISVRADGNP-PSITY-TWTKDGLPITQSSYSSG 214
+ V AP +Y V + + + ++ A G P P +T+ + T +P + Y
Sbjct: 2339 VKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKY--- 2395
Query: 215 NDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANP 274
+I +G++L + K R D+G YTC NS G + + V+ + + N +
Sbjct: 2396 --QIYQDGTLL-IQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTV 2452
Query: 275 NEDA------VLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSY----LIIRKA 324
E A ++ C A G P + W + P + +T + L IR
Sbjct: 2453 REIAAGGSRKLIDCKAEGIP--TPRVLWAFPEGVVLP--APYYGNRITVHGNGSLDIRSL 2508
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVK-FKPEMDTSPNFVKSASNVGQVGRLMCKCKS 383
+ + C+ N G A + +++ + + P K + G L C
Sbjct: 2509 RKSDSVQLVCMARNEGGEARLIVQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAG 2568
Query: 384 VPAPSFTWS-KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNE 442
P PS W NG L + F +HK D +L I+ +++ D G+Y C ARN
Sbjct: 2569 TPTPSLVWVLPNGTDLQSGQQLQRF--YHKAD-----GMLHISGLSSVDAGAYRCVARNA 2621
Query: 443 LGFSTTTVKLDVTSAPD--QVVSLTVTNVTHSTVTLEWV-PGFDGGLQSW 489
G + V L V P+ + V+ + T+ L PG G SW
Sbjct: 2622 AGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSW 2671
Score = 52.0 bits (119), Expect = 8e-06
Identities = 68/292 (23%), Positives = 108/292 (36%), Gaps = 25/292 (8%)
Query: 182 LIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTC 240
L + A G+P P I + + S+ S ++ + G+++ + +T DAG Y C
Sbjct: 2164 LKLDCSASGDPWPRILWRLPSKRMIDALFSFDS-RIKVFANGTLV-VKSVTDKDAGDYLC 2221
Query: 241 EAVNSQGAAVANISVSVHY-PAGIKSVSQNV-VANPNEDAVLSCTAIGNPLLAEHIKWER 298
A N G + V V PA I+ +N D + C A G P I W
Sbjct: 2222 VARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLP--NPEISWSL 2279
Query: 299 K-GYKIDPKSVTFEPKNLTSYLII--------RKAKSENLGNFQCVVNNGIGSATKQDVM 349
G ++ + + T ++ + G++ C N +G + V
Sbjct: 2280 PDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGK-DEMRVR 2338
Query: 350 LIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAE 409
+ V P + ++ G V + C+ K P P TW K+ +S KY
Sbjct: 2339 VKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKY--- 2395
Query: 410 FHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQV 461
I LLI SD G+Y C RN G TV + V P ++
Sbjct: 2396 -----QIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKI 2442
Score = 41.1 bits (92), Expect = 0.016
Identities = 37/119 (31%), Positives = 49/119 (41%), Gaps = 12/119 (10%)
Query: 355 KPEMDT-SPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSK--NGVKLPVNTSTKYFAEFH 411
KP++ T SP V + V C+ P P TW+K G + NT + F E
Sbjct: 1852 KPQILTKSPQTVSVTAETDTV--FPCEATGKPKPFVTWTKVSTGALMTPNTRIQRF-EVL 1908
Query: 412 KNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTNVT 470
KN L+I V D G Y C A N G V L VT Q+++ +VT
Sbjct: 1909 KN------GTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVT 1961
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 77.8 bits (183), Expect = 1e-13
Identities = 82/293 (27%), Positives = 129/293 (44%), Gaps = 33/293 (11%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTK-DGLPITQSSYSSGNDRIISEGSMLNMTKLT 231
NT + E + + A G+PP +WT+ D P+ + I+ L + +
Sbjct: 367 NTEVLVGESVTLECSATGHPPP-RISWTRGDRTPLPVDPRVN-----ITPSGGLYIQNVV 420
Query: 232 RHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA 291
+ D+G Y C A N+ + A + V Q+ V + C A GNP
Sbjct: 421 QGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNP--P 478
Query: 292 EHIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
I W + G ++ SV L+S L I + G ++C N IGS Q V+
Sbjct: 479 PVIAWTKGGSQL---SVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGS---QKVVA 532
Query: 351 IVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
+ +P + +P F S+ VG +L C + P P+ TW+K+GV+ V S K+
Sbjct: 533 HLTVQPRV--TPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQ--VTESGKF 588
Query: 407 FAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
HI+ L IN+V +D G YEC ARN +G ++ ++ L V + PD
Sbjct: 589 --------HISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV-NVPD 632
Score = 68.5 bits (160), Expect = 9e-11
Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I VQ P F T + V IE + + A GNPP + WTK G S S
Sbjct: 444 IIVQALPQFT-VTPQDRVVIEGQTVDFQCEAKGNPPPV-IAWTKGG-----SQLSVDRRH 496
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGA--AVANISVSVHYPAGIKSVSQNVVANPN 275
++ L ++ + HD G Y C+AVN G+ VA+++V S+ +
Sbjct: 497 LVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVG 556
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
+ L C++ G P A I W + G ++ +S F + +L I + G ++CV
Sbjct: 557 ANVQLPCSSQGEPEPA--ITWNKDGVQV-TESGKFH-ISPEGFLTINDVGPADAGRYECV 612
Query: 336 VNNGIGSATKQDVMLI 351
N IGSA+ V+ +
Sbjct: 613 ARNTIGSASVSMVLSV 628
Score = 55.6 bits (128), Expect = 7e-07
Identities = 58/225 (25%), Positives = 88/225 (39%), Gaps = 22/225 (9%)
Query: 246 QGAAVANIS---VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
QG +VA I+ ++ P I S Q+ +C A GNP I W R +
Sbjct: 246 QGRSVATITPEELNCERPR-ITSEPQDADVTSGNTVYFTCRAEGNP--KPEIIWLRNNNE 302
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSP 362
+ K+ + L+I+ + + G +QC+ N G Q+V L P P
Sbjct: 303 LSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSP---ARP 359
Query: 363 NFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
FV N VG+ L C P P +W++ G + P+ + +IT
Sbjct: 360 TFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRV--------NITP 410
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
+ L I NV D G Y C A N + T + V + P V+
Sbjct: 411 SGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVT 455
Score = 41.9 bits (94), Expect = 0.009
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 5/137 (3%)
Query: 21 PSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEI 80
P+ P T + G L C +TG +P ++W + D+ + S +
Sbjct: 356 PARPTFVIQPQNTEVLVGESVTLECSATG-HPPPRISWTRGDRTPLPVDPRVNITPSGGL 414
Query: 81 SILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLIC 140
I V + +Y C ATN+ + T + V P+ V + V+ G C
Sbjct: 415 YIQNVVQGDSGEYACSATNNIDSV--HATAFIIVQALPQ-FTVTPQDRVVIEGQTVDFQC 471
Query: 141 DSASSNPPATLSWWRDG 157
+ A NPP ++W + G
Sbjct: 472 E-AKGNPPPVIAWTKGG 487
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 77.8 bits (183), Expect = 1e-13
Identities = 82/293 (27%), Positives = 129/293 (44%), Gaps = 33/293 (11%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTK-DGLPITQSSYSSGNDRIISEGSMLNMTKLT 231
NT + E + + A G+PP +WT+ D P+ + I+ L + +
Sbjct: 345 NTEVLVGESVTLECSATGHPPP-RISWTRGDRTPLPVDPRVN-----ITPSGGLYIQNVV 398
Query: 232 RHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA 291
+ D+G Y C A N+ + A + V Q+ V + C A GNP
Sbjct: 399 QGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNP--P 456
Query: 292 EHIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
I W + G ++ SV L+S L I + G ++C N IGS Q V+
Sbjct: 457 PVIAWTKGGSQL---SVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGS---QKVVA 510
Query: 351 IVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
+ +P + +P F S+ VG +L C + P P+ TW+K+GV+ V S K+
Sbjct: 511 HLTVQPRV--TPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQ--VTESGKF 566
Query: 407 FAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
HI+ L IN+V +D G YEC ARN +G ++ ++ L V + PD
Sbjct: 567 --------HISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV-NVPD 610
Score = 68.5 bits (160), Expect = 9e-11
Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I VQ P F T + V IE + + A GNPP + WTK G S S
Sbjct: 422 IIVQALPQFT-VTPQDRVVIEGQTVDFQCEAKGNPPPV-IAWTKGG-----SQLSVDRRH 474
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGA--AVANISVSVHYPAGIKSVSQNVVANPN 275
++ L ++ + HD G Y C+AVN G+ VA+++V S+ +
Sbjct: 475 LVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVG 534
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
+ L C++ G P A I W + G ++ +S F + +L I + G ++CV
Sbjct: 535 ANVQLPCSSQGEPEPA--ITWNKDGVQV-TESGKFH-ISPEGFLTINDVGPADAGRYECV 590
Query: 336 VNNGIGSATKQDVMLI 351
N IGSA+ V+ +
Sbjct: 591 ARNTIGSASVSMVLSV 606
Score = 55.6 bits (128), Expect = 7e-07
Identities = 58/225 (25%), Positives = 88/225 (39%), Gaps = 22/225 (9%)
Query: 246 QGAAVANIS---VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
QG +VA I+ ++ P I S Q+ +C A GNP I W R +
Sbjct: 224 QGRSVATITPEELNCERPR-ITSEPQDADVTSGNTVYFTCRAEGNP--KPEIIWLRNNNE 280
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSP 362
+ K+ + L+I+ + + G +QC+ N G Q+V L P P
Sbjct: 281 LSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSP---ARP 337
Query: 363 NFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
FV N VG+ L C P P +W++ G + P+ + +IT
Sbjct: 338 TFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRV--------NITP 388
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
+ L I NV D G Y C A N + T + V + P V+
Sbjct: 389 SGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVT 433
Score = 41.9 bits (94), Expect = 0.009
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 5/137 (3%)
Query: 21 PSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEI 80
P+ P T + G L C +TG +P ++W + D+ + S +
Sbjct: 334 PARPTFVIQPQNTEVLVGESVTLECSATG-HPPPRISWTRGDRTPLPVDPRVNITPSGGL 392
Query: 81 SILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLIC 140
I V + +Y C ATN+ + T + V P+ V + V+ G C
Sbjct: 393 YIQNVVQGDSGEYACSATNNIDSV--HATAFIIVQALPQ-FTVTPQDRVVIEGQTVDFQC 449
Query: 141 DSASSNPPATLSWWRDG 157
+ A NPP ++W + G
Sbjct: 450 E-AKGNPPPVIAWTKGG 465
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 77.8 bits (183), Expect = 1e-13
Identities = 82/293 (27%), Positives = 129/293 (44%), Gaps = 33/293 (11%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTK-DGLPITQSSYSSGNDRIISEGSMLNMTKLT 231
NT + E + + A G+PP +WT+ D P+ + I+ L + +
Sbjct: 367 NTEVLVGESVTLECSATGHPPP-RISWTRGDRTPLPVDPRVN-----ITPSGGLYIQNVV 420
Query: 232 RHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLA 291
+ D+G Y C A N+ + A + V Q+ V + C A GNP
Sbjct: 421 QGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNP--P 478
Query: 292 EHIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
I W + G ++ SV L+S L I + G ++C N IGS Q V+
Sbjct: 479 PVIAWTKGGSQL---SVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGS---QKVVA 532
Query: 351 IVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKY 406
+ +P + +P F S+ VG +L C + P P+ TW+K+GV+ V S K+
Sbjct: 533 HLTVQPRV--TPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQ--VTESGKF 588
Query: 407 FAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD 459
HI+ L IN+V +D G YEC ARN +G ++ ++ L V + PD
Sbjct: 589 --------HISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV-NVPD 632
Score = 68.5 bits (160), Expect = 9e-11
Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I VQ P F T + V IE + + A GNPP + WTK G S S
Sbjct: 444 IIVQALPQFT-VTPQDRVVIEGQTVDFQCEAKGNPPPV-IAWTKGG-----SQLSVDRRH 496
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGA--AVANISVSVHYPAGIKSVSQNVVANPN 275
++ L ++ + HD G Y C+AVN G+ VA+++V S+ +
Sbjct: 497 LVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVG 556
Query: 276 EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCV 335
+ L C++ G P A I W + G ++ +S F + +L I + G ++CV
Sbjct: 557 ANVQLPCSSQGEPEPA--ITWNKDGVQV-TESGKFH-ISPEGFLTINDVGPADAGRYECV 612
Query: 336 VNNGIGSATKQDVMLI 351
N IGSA+ V+ +
Sbjct: 613 ARNTIGSASVSMVLSV 628
Score = 55.6 bits (128), Expect = 7e-07
Identities = 58/225 (25%), Positives = 88/225 (39%), Gaps = 22/225 (9%)
Query: 246 QGAAVANIS---VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYK 302
QG +VA I+ ++ P I S Q+ +C A GNP I W R +
Sbjct: 246 QGRSVATITPEELNCERPR-ITSEPQDADVTSGNTVYFTCRAEGNP--KPEIIWLRNNNE 302
Query: 303 IDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSP 362
+ K+ + L+I+ + + G +QC+ N G Q+V L P P
Sbjct: 303 LSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSP---ARP 359
Query: 363 NFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
FV N VG+ L C P P +W++ G + P+ + +IT
Sbjct: 360 TFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRV--------NITP 410
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVS 463
+ L I NV D G Y C A N + T + V + P V+
Sbjct: 411 SGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVT 455
Score = 41.9 bits (94), Expect = 0.009
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 5/137 (3%)
Query: 21 PSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEI 80
P+ P T + G L C +TG +P ++W + D+ + S +
Sbjct: 356 PARPTFVIQPQNTEVLVGESVTLECSATG-HPPPRISWTRGDRTPLPVDPRVNITPSGGL 414
Query: 81 SILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKPGIEATLIC 140
I V + +Y C ATN+ + T + V P+ V + V+ G C
Sbjct: 415 YIQNVVQGDSGEYACSATNNIDSV--HATAFIIVQALPQ-FTVTPQDRVVIEGQTVDFQC 471
Query: 141 DSASSNPPATLSWWRDG 157
+ A NPP ++W + G
Sbjct: 472 E-AKGNPPPVIAWTKGG 487
>AF109126-1|AAD43217.1| 398|Homo sapiens stromal cell-derived
receptor-1 beta protein.
Length = 398
Score = 77.0 bits (181), Expect = 3e-13
Identities = 69/249 (27%), Positives = 111/249 (44%), Gaps = 27/249 (10%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNS-------QGAAV----ANISVSVHYPAGIKSVSQNVV 271
S+L +T+LT D+G Y C A N Q ++ A ++SV I + + ++
Sbjct: 99 SVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVII 158
Query: 272 AN-PNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLG 330
+ P L C + + W + G ++ S T + + Y I K ++E+ G
Sbjct: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL---SATRKNASNMEYRI-NKPRAEDSG 214
Query: 331 NFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFT 390
+ CV + SA K + + VK P D + + N GQ + CK P P +
Sbjct: 215 EYHCVYH--FVSAPKANATIEVKAAP--DITGHKRSENKNEGQDATMYCKSVGYPHPDWI 270
Query: 391 WSK--NGVKLP-VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFST 447
W K NG+ + VNTS ++F +N YT + ++N T D G YEC A N +G ++
Sbjct: 271 WRKKENGMPMDIVNTSGRFFIINKEN----YTELNIVNLQITEDPGEYECNATNAIGSAS 326
Query: 448 TTVKLDVTS 456
L V S
Sbjct: 327 VVTVLRVRS 335
Score = 32.3 bits (70), Expect = 7.3
Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 17/130 (13%)
Query: 5 KDSGIFKCMINSPSDPPS--------APMITGYVPGTTLAAGTVQKLACISTGGNPLATL 56
+DSG + C+ + S P + AP ITG+ G + C S G P
Sbjct: 211 EDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVG-YPHPDW 269
Query: 57 TWFKNDKKIHSTTKTT-------DKAVSAEISILT-NVTDNQAQYRCEATNSATEIPLFE 108
W K + + T +K E++I+ +T++ +Y C ATN+ +
Sbjct: 270 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
Query: 109 TVTLNVHFAP 118
+ + H AP
Sbjct: 330 VLRVRSHLAP 339
>AF005070-1|AAB61615.1| 348|Homo sapiens neural cell adhesion
molecule protein.
Length = 348
Score = 77.0 bits (181), Expect = 3e-13
Identities = 60/239 (25%), Positives = 100/239 (41%), Gaps = 12/239 (5%)
Query: 223 SMLNMTKLTRHDAGIYTCEAVNSQGA-AVANISVSVHYPAGIKSVSQNVVANPNEDAVLS 281
S L + DAGIY C G+ + A ++V + K+ EDAV+
Sbjct: 79 STLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIV 138
Query: 282 CTAIGNPLLAEHIKWERKGYKID-PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNN-G 339
C + + L I W+ KG + K V F + +YL I K + G ++C
Sbjct: 139 CDVVSS--LPPTIIWKHKGRDVILKKDVRFIFLS-NNYLPIPGIKKTDEGTYRCEGRILA 195
Query: 340 IGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLP 399
G D+ +IV P + N V + +N+GQ L+C + P P+ +W+K+G ++
Sbjct: 196 RGEINFNDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPGPTMSWTKDGEQIE 255
Query: 400 VNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+ + + H+T I V + C A N++G T+ L V + P
Sbjct: 256 QEEHDEKYLFSDDSSHLT------IKKVDKNHEAENICIAENKVGEQDATIHLKVFAKP 308
Score = 35.5 bits (78), Expect = 0.79
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 3/111 (2%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
P T +WTKDG I Q + + S L + K+ ++ C A N G A
Sbjct: 241 PGPTMSWTKDGEQIEQEEHDE-KYLFSDDSSHLTIKKVDKNHEAENICIAENKVGEQDAT 299
Query: 253 ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKI 303
I + V I V E +L+ A G+ + +I W ++I
Sbjct: 300 IHLKVFAKPQITYVEDQTAMELAEQVILTVEASGDHI--PYITWWTSTWQI 348
>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
phosphatase, receptor type, D isoform 4 precursor
variant protein.
Length = 1478
Score = 76.6 bits (180), Expect = 3e-13
Identities = 101/408 (24%), Positives = 161/408 (39%), Gaps = 46/408 (11%)
Query: 170 TSYNTVGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMT 228
T + G+ +A G+P P I W K G ++ + + GS+L +
Sbjct: 5 TPVDQTGVSGGVASFICQATGDPRPKIV--WNKKGKKVSNQRFEV-IEFDDGSGSVLRIQ 61
Query: 229 KL-TRHDAGIYTCEAVNSQGAAVANISVSV----HYPAGIKSVS---QNVVANPNEDAVL 280
L T D IY C A N+ G + ++V P G ++ Q V A +
Sbjct: 62 PLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATM 121
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTS-------YLIIRKAKSENLGNFQ 333
C A GNP I W + +D + K L S L I +++ + G ++
Sbjct: 122 LCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYE 179
Query: 334 CVVNNGIGSATKQDVMLIVKFKPEMD-TSPNFVKSASN----VGQVGRLMCKCKSVPAPS 388
CV N G+ L V+ E+ P F +N G + C P P
Sbjct: 180 CVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPY 239
Query: 389 FTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTT 448
W L ++D +VL +N+V S +Y C A + LG
Sbjct: 240 VKWMLGAEDLTP-----------EDDMPIGRNVLELNDVRQS--ANYTCVAMSTLGVIEA 286
Query: 449 TVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSWYRIRYR-KVFDDSYKYEDV 507
++ V + P + VT T +++TL W G + S+Y I+++ K ++ YK D
Sbjct: 287 IAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPV-SYYIIQHKPKNSEELYKEIDG 345
Query: 508 LPKHATNFTVHGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSE 555
+ T ++V GL +DY F V+A+N IG+ P T TS +
Sbjct: 346 VA--TTRYSVAGLSPYSDYEFRVVAVNNIGRG---PPSEPVLTQTSEQ 388
Score = 42.7 bits (96), Expect = 0.005
Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 10/138 (7%)
Query: 34 TLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEISILT----NVTDN 89
T +G V C +TG +P + W K KK+ + + S+L +
Sbjct: 10 TGVSGGVASFICQATG-DPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRD 68
Query: 90 QAQYRCEATNSATEIPLFETVT-LNVHFAPEA---VKVRAEPDVLKPGIEATLICDSASS 145
+A Y C A+N+ EI + +T L P + + + V++ AT++C +AS
Sbjct: 69 EAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLC-AASG 127
Query: 146 NPPATLSWWRDGIPVQNA 163
NP ++W++D +PV +
Sbjct: 128 NPDPEITWFKDFLPVDTS 145
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 75.4 bits (177), Expect = 8e-13
Identities = 96/415 (23%), Positives = 170/415 (40%), Gaps = 38/415 (9%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTK--DGLPITQSSYSSGNDRIISEGSMLNMTKL 230
N V IE + ++ G PP ++TW + + + + YS + GS L ++ +
Sbjct: 248 NVVAIEGKDAVLECCVSGYPPP-SFTWLRGEEVIQLRSKKYS------LLGGSNLLISNV 300
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLL 290
T D+G+YTC A+ ++V P + N+ A + D CT G P+
Sbjct: 301 TDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPV- 359
Query: 291 AEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
+ W + G + P S F+ ++ I+ KS+ G +QCV N G+A + L
Sbjct: 360 -PTVNWMKNGDVVIP-SDYFQIVGGSNLRILGVVKSDE-GFYQCVAENEAGNA-QTSAQL 415
Query: 351 IVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG-VKLPVNTSTKYFAE 409
IV KP + +S + + SA V ++ + V +W K + T T +F+
Sbjct: 416 IVP-KPAIPSS-SVLPSAPR--DVVPVLVSSRFV---RLSWRPPAEAKGNIQTFTVFFSR 468
Query: 410 FHKNDHITYTSV------LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD---- 459
N + L + N+ ++ A NE G ++ + V + P+
Sbjct: 469 EGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVP 528
Query: 460 -QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTV 517
V +L + + +++ + W P + G YR+ +V S E + ++ +
Sbjct: 529 GPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTEV---STGKEQNIEVDGLSYKL 585
Query: 518 HGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDI 572
GL+K T+Y +A N+ G DD TL+ VS E V + I
Sbjct: 586 EGLKKFTEYSLRFLAYNRYGPG-VSTDDITVVTLSDVPSAPPQNVSLEVVNSRSI 639
Score = 72.5 bits (170), Expect = 6e-12
Identities = 75/270 (27%), Positives = 116/270 (42%), Gaps = 26/270 (9%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRH---D 234
N L S +D P I W KDG+ + + +S GS+L L +RH D
Sbjct: 56 NVLLDCSAESDRGVPVIK--WKKDGIHLALGM--DERKQQLSNGSLLIQNILHSRHHKPD 111
Query: 235 AGIYTCEA-VNSQGAAVANIS-VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
G+Y CEA + G+ ++ + V+V P S +++V A + +L C IG P+
Sbjct: 112 EGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTI 171
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI 351
H W++ + P L S L I + + ++G ++C N S T + +
Sbjct: 172 H--WQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVR 229
Query: 352 VKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYF 407
+ P + F++ SNV G+ L C P PSFTW + G ++ S KY
Sbjct: 230 ILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKY- 287
Query: 408 AEFHKNDHITYTSVLLINNVATSDYGSYEC 437
+ S LLI+NV D G Y C
Sbjct: 288 -------SLLGGSNLLISNVTDDDSGMYTC 310
Score = 66.9 bits (156), Expect = 3e-10
Identities = 95/369 (25%), Positives = 146/369 (39%), Gaps = 50/369 (13%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGS-MLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T W K+ +T G+ R++ S L +++L D GIY C A N +
Sbjct: 167 PMPTIHWQKNQQDLTPIP---GDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTG 223
Query: 252 NISV-------SVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID 304
N + +H NVVA +DAVL C G P W R I
Sbjct: 224 NEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYP--PPSFTWLRGEEVIQ 281
Query: 305 PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV---NNGIGSATKQDVMLIVKFKPEMDTS 361
+S + S L+I ++ G + CVV N I ++ + V++ P
Sbjct: 282 LRSKKYSLLG-GSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLV----PPWFLNH 336
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
P+ + + ++ C P P+ W KNG V + YF I S
Sbjct: 337 PSNLYAYESMDI--EFECTVSGKPVPTVNWMKNG---DVVIPSDYF-------QIVGGSN 384
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDV-----------TSAPDQVVSLTVTNVT 470
L I V SD G Y+C A NE G + T+ +L V SAP VV + V++
Sbjct: 385 LRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSS-- 442
Query: 471 HSTVTLEWVPGFD--GGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIF 528
V L W P + G +Q+ + + + + D+ + + + TV L+ Y F
Sbjct: 443 -RFVRLSWRPPAEAKGNIQT-FTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTF 500
Query: 529 SVMAINKIG 537
V+A N+ G
Sbjct: 501 RVVAYNEWG 509
Score = 33.1 bits (72), Expect = 4.2
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 445 FSTTTVKLDVTSAPDQVVSLTVTNVTHSTVTLEWVPGFDGGLQSW-----YRIRYRKVFD 499
F T+ L P V + +TH V + W Q Y +R+R F
Sbjct: 833 FPTSVPDLSTPMLPP--VGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFS 890
Query: 500 DSYKYEDVLPKHATNFTVHGLEKNTDYIFSVM 531
S KY+ + ++T GL+ NT Y FSVM
Sbjct: 891 ASAKYKSE-DTTSLSYTATGLKPNTMYEFSVM 921
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 75.4 bits (177), Expect = 8e-13
Identities = 91/383 (23%), Positives = 163/383 (42%), Gaps = 31/383 (8%)
Query: 175 VGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRH 233
V + + +++ A G P P+I + ++ L T+SS ++ G L ++ +T
Sbjct: 259 VRVIGQDVVLPCVASGLPTPTIKWMKNEEALD-TESS----ERLVLLAGGSLEISDVTED 313
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
DAG Y C A N A ++V N+ A+ + D V C G P
Sbjct: 314 DAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKP--TPT 371
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+KW + G + P S F+ + ++ KS+ G +QC+ N +G+A ++I++
Sbjct: 372 VKWVKNGDMVIP-SDYFKIVKEHNLQVLGLVKSDE-GFYQCIAENDVGNAQAGAQLIILE 429
Query: 354 FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKN 413
P T P + SA V + + + T + + + S Y E
Sbjct: 430 HAP-ATTGP--LPSAPR--DVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIAR 484
Query: 414 DHITYTS-----VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
+ + TS + I N+ + + A+N+ G ++ L V + P+ + N
Sbjct: 485 ERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPN 544
Query: 469 V-------THSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLE 521
+ T TVT E +G +Q+ Y++ Y + D + DV + ++T++GL+
Sbjct: 545 LRAYAASPTSITVTWETPVSGNGEIQN-YKLYYMEKGTDKEQDVDV---SSHSYTINGLK 600
Query: 522 KNTDYIFSVMAINKIGQSKYRPD 544
K T+Y F V+A NK G PD
Sbjct: 601 KYTEYSFRVVAYNKHGPGVSTPD 623
Score = 65.3 bits (152), Expect = 9e-10
Identities = 88/348 (25%), Positives = 138/348 (39%), Gaps = 41/348 (11%)
Query: 215 NDRIISEGS-MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNV-VA 272
+DR+I S ML ++ T D G+Y C V S G + V + + +S V +
Sbjct: 195 DDRVIKLPSGMLVISNATEGDGGLYRC-VVESGGPPKYSDEVELKVLPDPEVISDLVFLK 253
Query: 273 NPN-------EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAK 325
P+ +D VL C A G P IKW + +D +S L I
Sbjct: 254 QPSPLVRVIGQDVVLPCVASGLP--TPTIKWMKNEEALDTESSERLVLLAGGSLEISDVT 311
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVP 385
++ G + C+ +NG + L V+ +PE P + + ++ V C+ P
Sbjct: 312 EDDAGTYFCIADNG-NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV--FECEVTGKP 368
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF 445
P+ W KNG + + YF +++ L + + SD G Y+C A N++G
Sbjct: 369 TPTVKWVKNGDMV---IPSDYFKIVKEHN-------LQVLGLVKSDEGFYQCIAENDVGN 418
Query: 446 STTTVKLDVT-----------SAPDQVVSLTVTNVTHSTVTLEW-VPGFDG-GLQSWYRI 492
+ +L + SAP VV+ V+ + L W P D G Y +
Sbjct: 419 AQAGAQLIILEHAPATTGPLPSAPRDVVASLVST---RFIKLTWRTPASDPHGDNLTYSV 475
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y K + E+ T+ L T YIF VMA NK G +
Sbjct: 476 FYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGE 523
Score = 64.1 bits (149), Expect = 2e-09
Identities = 92/386 (23%), Positives = 165/386 (42%), Gaps = 44/386 (11%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSML--NM--T 228
+T+ + +I++ A P S W KDG + + S +++ +GS+ N+ +
Sbjct: 61 DTLSVRGSSVILNCSAYSEP-SPKIEWKKDGTFL--NLVSDDRRQLLPDGSLFISNVVHS 117
Query: 229 KLTRHDAGIYTCEA-VNSQGAAVANISVSVHYPAGI-KSVSQNVVAN--PNEDAVLSCTA 284
K + D G Y C A V S G ++ + + AG+ + SQ ++ +A+L+C
Sbjct: 118 KHNKPDEGYYQCVATVESLGTIISRTAKLI--VAGLPRFTSQPEPSSVYAGNNAILNCEV 175
Query: 285 IGNPLLAEHIKWE--RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
N L ++WE R+ +D + + P + L+I A + G ++CVV +G
Sbjct: 176 --NADLVPFVRWEQNRQPLLLDDRVIKL-PSGM---LVISNATEGDGGLYRCVVESGGPP 229
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+V L V PE+ + F+K S +GQ L C +P P+ W KN L
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+S + + L I++V D G+Y C A N G T + ++T
Sbjct: 290 DTESSERLV--------LLAGGSLEISDVTEDDAGTYFCIADN--GNETIEAQAELTVQA 339
Query: 459 DQVVSLTVTNV-THSTVTLEW---VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATN 514
TN+ H ++ + + V G W + + D +K ++ +H N
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFK---IVKEH--N 394
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
V GL K+ + + +A N +G ++
Sbjct: 395 LQVLGLVKSDEGFYQCIAENDVGNAQ 420
Score = 47.6 bits (108), Expect = 2e-04
Identities = 93/388 (23%), Positives = 150/388 (38%), Gaps = 51/388 (13%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N E+ ++ G P T W K+G + S Y +I+ E + L + L +
Sbjct: 349 NIYAHESMDIVFECEVTGKPTP-TVKWVKNGDMVIPSDYF----KIVKEHN-LQVLGLVK 402
Query: 233 HDAGIYTCEAVNSQGAAVANISVSV--HYPAG---IKSVSQNVVANPNEDAVLSCT---A 284
D G Y C A N G A A + + H PA + S ++VVA+ + T
Sbjct: 403 SDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTP 462
Query: 285 IGNPL---LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
+P L + + ++G + T P + + I+ + F+ + N G
Sbjct: 463 ASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQ--VTIQNLMPATVYIFRVMAQNKHG 520
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW----SKNGVK 397
S + L V+ +PE+ G L S + + TW S NG
Sbjct: 521 SG-ESSAPLRVETQPEVQLP----------GPAPNLRAYAASPTSITVTWETPVSGNG-- 567
Query: 398 LPVNTSTKYFAE--FHKNDHITYTS-VLLINNVATSDYGSYECGARNELG--FSTTTVKL 452
+ Y+ E K + +S IN + S+ A N+ G ST V +
Sbjct: 568 -EIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAV 626
Query: 453 ----DVTSAPDQVVSLTVTNVTHSTVTLEW---VPGFDGGLQSWYRIRYRKVFDDSYKYE 505
DV SA Q +SL V N ++ + W P G + Y+IRYRK S E
Sbjct: 627 RTLSDVPSAAPQNLSLEVRN--SKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTE 684
Query: 506 DVLPKHATNFTVHGLEKNTDYIFSVMAI 533
++ + + GL++ T+Y F V A+
Sbjct: 685 TLVSGTQLSQLIEGLDRGTEYNFRVAAL 712
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 75.4 bits (177), Expect = 8e-13
Identities = 91/383 (23%), Positives = 163/383 (42%), Gaps = 31/383 (8%)
Query: 175 VGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRH 233
V + + +++ A G P P+I + ++ L T+SS ++ G L ++ +T
Sbjct: 259 VRVIGQDVVLPCVASGLPTPTIKWMKNEEALD-TESS----ERLVLLAGGSLEISDVTED 313
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
DAG Y C A N A ++V N+ A+ + D V C G P
Sbjct: 314 DAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKP--TPT 371
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+KW + G + P S F+ + ++ KS+ G +QC+ N +G+A ++I++
Sbjct: 372 VKWVKNGDMVIP-SDYFKIVKEHNLQVLGLVKSDE-GFYQCIAENDVGNAQAGAQLIILE 429
Query: 354 FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKN 413
P T P + SA V + + + T + + + S Y E
Sbjct: 430 HAP-ATTGP--LPSAPR--DVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIAR 484
Query: 414 DHITYTS-----VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
+ + TS + I N+ + + A+N+ G ++ L V + P+ + N
Sbjct: 485 ERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPN 544
Query: 469 V-------THSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLE 521
+ T TVT E +G +Q+ Y++ Y + D + DV + ++T++GL+
Sbjct: 545 LRAYAASPTSITVTWETPVSGNGEIQN-YKLYYMEKGTDKEQDVDV---SSHSYTINGLK 600
Query: 522 KNTDYIFSVMAINKIGQSKYRPD 544
K T+Y F V+A NK G PD
Sbjct: 601 KYTEYSFRVVAYNKHGPGVSTPD 623
Score = 65.3 bits (152), Expect = 9e-10
Identities = 88/348 (25%), Positives = 138/348 (39%), Gaps = 41/348 (11%)
Query: 215 NDRIISEGS-MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNV-VA 272
+DR+I S ML ++ T D G+Y C V S G + V + + +S V +
Sbjct: 195 DDRVIKLPSGMLVISNATEGDGGLYRC-VVESGGPPKYSDEVELKVLPDPEVISDLVFLK 253
Query: 273 NPN-------EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAK 325
P+ +D VL C A G P IKW + +D +S L I
Sbjct: 254 QPSPLVRVIGQDVVLPCVASGLP--TPTIKWMKNEEALDTESSERLVLLAGGSLEISDVT 311
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVP 385
++ G + C+ +NG + L V+ +PE P + + ++ V C+ P
Sbjct: 312 EDDAGTYFCIADNG-NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV--FECEVTGKP 368
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF 445
P+ W KNG + + YF +++ L + + SD G Y+C A N++G
Sbjct: 369 TPTVKWVKNGDMV---IPSDYFKIVKEHN-------LQVLGLVKSDEGFYQCIAENDVGN 418
Query: 446 STTTVKLDVT-----------SAPDQVVSLTVTNVTHSTVTLEW-VPGFDG-GLQSWYRI 492
+ +L + SAP VV+ V+ + L W P D G Y +
Sbjct: 419 AQAGAQLIILEHAPATTGPLPSAPRDVVASLVST---RFIKLTWRTPASDPHGDNLTYSV 475
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y K + E+ T+ L T YIF VMA NK G +
Sbjct: 476 FYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGE 523
Score = 63.3 bits (147), Expect = 3e-09
Identities = 92/386 (23%), Positives = 164/386 (42%), Gaps = 44/386 (11%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSML--NM--T 228
+T+ + +I++ A P S W KDG + + S +++ +GS+ N+ +
Sbjct: 61 DTLSVRGSSVILNCSAYSEP-SPKIEWKKDGTFL--NLVSDDRRQLLPDGSLFISNVVHS 117
Query: 229 KLTRHDAGIYTCEA-VNSQGAAVANISVSVHYPAGI-KSVSQNVVAN--PNEDAVLSCTA 284
K + D G Y C A V S G ++ + + AG+ + SQ ++ A+L+C
Sbjct: 118 KHNKPDEGYYQCVATVESLGTIISRTAKLI--VAGLPRFTSQPEPSSVYAGNGAILNCEV 175
Query: 285 IGNPLLAEHIKWE--RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
N L ++WE R+ +D + + P + L+I A + G ++CVV +G
Sbjct: 176 --NADLVPFVRWEQNRQPLLLDDRVIKL-PSGM---LVISNATEGDGGLYRCVVESGGPP 229
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+V L V PE+ + F+K S +GQ L C +P P+ W KN L
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+S + + L I++V D G+Y C A N G T + ++T
Sbjct: 290 DTESSERLV--------LLAGGSLEISDVTEDDAGTYFCIADN--GNETIEAQAELTVQA 339
Query: 459 DQVVSLTVTNV-THSTVTLEW---VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATN 514
TN+ H ++ + + V G W + + D +K ++ +H N
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFK---IVKEH--N 394
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
V GL K+ + + +A N +G ++
Sbjct: 395 LQVLGLVKSDEGFYQCIAENDVGNAQ 420
Score = 47.6 bits (108), Expect = 2e-04
Identities = 93/388 (23%), Positives = 150/388 (38%), Gaps = 51/388 (13%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N E+ ++ G P T W K+G + S Y +I+ E + L + L +
Sbjct: 349 NIYAHESMDIVFECEVTGKPTP-TVKWVKNGDMVIPSDYF----KIVKEHN-LQVLGLVK 402
Query: 233 HDAGIYTCEAVNSQGAAVANISVSV--HYPAG---IKSVSQNVVANPNEDAVLSCT---A 284
D G Y C A N G A A + + H PA + S ++VVA+ + T
Sbjct: 403 SDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTP 462
Query: 285 IGNPL---LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
+P L + + ++G + T P + + I+ + F+ + N G
Sbjct: 463 ASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQ--VTIQNLMPATVYIFRVMAQNKHG 520
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW----SKNGVK 397
S + L V+ +PE+ G L S + + TW S NG
Sbjct: 521 SG-ESSAPLRVETQPEVQLP----------GPAPNLRAYAASPTSITVTWETPVSGNG-- 567
Query: 398 LPVNTSTKYFAE--FHKNDHITYTS-VLLINNVATSDYGSYECGARNELG--FSTTTVKL 452
+ Y+ E K + +S IN + S+ A N+ G ST V +
Sbjct: 568 -EIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAV 626
Query: 453 ----DVTSAPDQVVSLTVTNVTHSTVTLEW---VPGFDGGLQSWYRIRYRKVFDDSYKYE 505
DV SA Q +SL V N ++ + W P G + Y+IRYRK S E
Sbjct: 627 RTLSDVPSAAPQNLSLEVRN--SKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTE 684
Query: 506 DVLPKHATNFTVHGLEKNTDYIFSVMAI 533
++ + + GL++ T+Y F V A+
Sbjct: 685 TLVSGTQLSQLIEGLDRGTEYNFRVAAL 712
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 75.4 bits (177), Expect = 8e-13
Identities = 66/258 (25%), Positives = 101/258 (39%), Gaps = 22/258 (8%)
Query: 207 TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSV 266
T++ N I GS++ + + G Y C A N+ G A + +++SVH P + +
Sbjct: 3058 TRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVL 3117
Query: 267 SQNVV-ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKA 324
+ V + L C + G P +W R + T+ + + L I A
Sbjct: 3118 PEGPVWVKVGKAVTLECVSAGEP--RSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSA 3175
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCK 380
K + G + C+ N +G+A KQ V +IV +P + + G L C
Sbjct: 3176 KPSDAGTYVCLAQNALGTAQKQ-VEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCS 3234
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
PAP+ WSK LP H L+I VA D G Y C A
Sbjct: 3235 ATGSPAPTIHWSKLRSPLPW-------------QHRLEGDTLIIPRVAQQDSGQYICNAT 3281
Query: 441 NELGFSTTTVKLDVTSAP 458
+ G + T+ L V S P
Sbjct: 3282 SPAGHAEATIILHVESPP 3299
Score = 65.7 bits (153), Expect = 6e-10
Identities = 61/246 (24%), Positives = 105/246 (42%), Gaps = 13/246 (5%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVL 280
EG L + ++ + D+G Y C A + G A A I + V P +V ++ E L
Sbjct: 3259 EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL 3318
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
C A G P L +W R G + ++ +N L +A E+ G ++C V N +
Sbjct: 3319 QCLAHGTPPLT--FQWSRVGSSLPGRATA---RN--ELLHFERAAPEDSGRYRCRVTNKV 3371
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV 400
GSA + L+V+ P + + ++ QV + + KS+ A V
Sbjct: 3372 GSA-EAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQL-ETKSIGAS--VEFHCAVPSDQ 3427
Query: 401 NTSTKYFAEFHK--NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T ++F E + H VL I N+ S G+Y C A G + + +L + + P
Sbjct: 3428 GTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALP 3487
Query: 459 DQVVSL 464
++++
Sbjct: 3488 SVLINI 3493
Score = 56.4 bits (130), Expect = 4e-07
Identities = 59/250 (23%), Positives = 101/250 (40%), Gaps = 26/250 (10%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVN----SQGAAVANISVSVHYPAGIKSVSQ-NVV 271
R + +L + + DAG Y C N QG A ++ S A + S+ +
Sbjct: 1817 RAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1876
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLG 330
P + A C+A G+P ++W G ++ K+ L + + +
Sbjct: 1877 VQPGQLAEFRCSATGSP--TPTLEWTGGPGGQLPAKAQIHG-----GILRLPAVEPTDQA 1929
Query: 331 NFQCVVNNGIGSATKQDVMLIVKFK-PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
+ C ++ G + V+ + P + SP ++ + G+ RL C+ VP+ +
Sbjct: 1930 QYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPE--RTQVHAGRTVRLYCRAAGVPSATI 1987
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
TW K G LP A + D T LLI + T+D G Y C A + G +
Sbjct: 1988 TWRKEGGSLPPQ------ARSERTDIAT----LLIPAITTADAGFYLCVATSPAGTAQAR 2037
Query: 450 VKLDVTSAPD 459
+++ V SA D
Sbjct: 2038 MQVVVLSASD 2047
Score = 55.6 bits (128), Expect = 7e-07
Identities = 80/323 (24%), Positives = 120/323 (37%), Gaps = 49/323 (15%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS T TW K+G + + S D + L + +T DAG Y C A + G A A
Sbjct: 1983 PSATITWRKEGGSLPPQARSERTDI-----ATLLIPAITTADAGFYLCVATSPAGTAQAR 2037
Query: 253 -----ISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS 307
+S S P G+K S + + L+C G+ + W R+G + P +
Sbjct: 2038 MQVVVLSASDASPPGVKIESSSPSVTEGQTLDLNCVVAGS--AHAQVTWYRRGGSLPPHT 2095
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG---SATKQDVMLIVKFKPEMDTSPNF 364
S L + + + G + C V NG G ++ V+ P P
Sbjct: 2096 QVH-----GSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGS 2150
Query: 365 VK------SASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ S+S+V GQ L C TW K G LP H
Sbjct: 2151 TRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPAR-------------HQ 2197
Query: 417 TYTSVLLINNVATSDYGSYEC---GARNELGFST-TTVKLDVTSA---PDQVVSLTVTNV 469
T+ S+L ++ V +D G Y C G L S T++ V P ++ S + T
Sbjct: 2198 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2257
Query: 470 THSTVTLEWVPGFDGGLQ-SWYR 491
T+ L V Q +WY+
Sbjct: 2258 EGQTLDLSCVVAGQAHAQVTWYK 2280
Score = 54.8 bits (126), Expect = 1e-06
Identities = 101/482 (20%), Positives = 177/482 (36%), Gaps = 72/482 (14%)
Query: 23 APMITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP++ P ++ G L C G+P W + D + + T + +E+
Sbjct: 1675 APLVVEVHPARSIVPQGGSHSLRC-QVSGSPPHYFYWSREDGR-PVPSGTQQRHQGSELH 1732
Query: 82 ILTNVTDNQAQYRCEATN-SATEIPLFETVTLNVHFAPEAVKVRAE-PDVLKPGIEATLI 139
+ + Y C N + E + P V V + ++PG + T I
Sbjct: 1733 FPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFI 1792
Query: 140 CDSASSNPPATLSWWR-------------DGI-PVQNAPIFDD----TTSYNTVGIENEP 181
C + S +P TL W R +GI ++N + D T N ++
Sbjct: 1793 CTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGT 1852
Query: 182 LIISVRADG---------NPPSIT--------YTWTKDGLPITQSSYSSGNDRIIS---- 220
+ V+A G +PP +T + + G P ++ G +
Sbjct: 1853 ATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQ 1912
Query: 221 -EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG--IKSVSQNVVANPNED 277
G +L + + D Y C A +S G VA + VH G ++ + +
Sbjct: 1913 IHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRT 1972
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
L C A G P + I W ++G + P++ + E ++ + L+I + + G + CV
Sbjct: 1973 VRLYCRAAGVP--SATITWRKEGGSLPPQARS-ERTDIAT-LLIPAITTADAGFYLCVAT 2028
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSASN-----VGQVGRLMCKCKSVPAPSFTWS 392
+ G+A + ++++ D SP VK S+ GQ L C TW
Sbjct: 2029 SPAGTAQARMQVVVLS---ASDASPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWY 2085
Query: 393 KNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKL 452
+ G LP +T + S L + V+ +D G Y C N G ++ +
Sbjct: 2086 RRGGSLPPHTQ-------------VHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITV 2132
Query: 453 DV 454
V
Sbjct: 2133 SV 2134
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/253 (24%), Positives = 100/253 (39%), Gaps = 42/253 (16%)
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH------------YPAGIKSVSQN 269
GS L + ++T D+G Y C V S G A++ V++ YP I+S S +
Sbjct: 2485 GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSAS 2544
Query: 270 VVANPNEDAVLSCTAIGNPLLAEH-IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
+ D L+C A H I W ++G S+ + + S L I + +
Sbjct: 2545 LANGHTLD--LNCLVASQ---APHTITWYKRG-----GSLPSRHQIVGSRLRIPQVTPAD 2594
Query: 329 LGNFQCVVNNGIGSATKQDVMLI----VKFKPEMDTSPNFVKSASNV--GQVGRLMCKCK 382
G + C V+NG GS ++ I P + S+ V GQ L C
Sbjct: 2595 SGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 2654
Query: 383 SVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNE 442
P TW K G LP + H T+ S L ++ ++ +D G Y C A N
Sbjct: 2655 RQPQAIITWYKRGGSLP-------------SRHQTHGSHLRLHQMSVADSGEYVCRANNN 2701
Query: 443 LGFSTTTVKLDVT 455
+ ++ + V+
Sbjct: 2702 IDALEASIVISVS 2714
Score = 52.4 bits (120), Expect = 6e-06
Identities = 59/246 (23%), Positives = 104/246 (42%), Gaps = 33/246 (13%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNEDAV 279
+ +L + L + G Y C+A G A A+ + + P+ + ++ +V AV
Sbjct: 3447 QDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAV 3506
Query: 280 -LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE--NLGNFQCVV 336
C A+G+P + W + G + P V S ++R A E + G ++C
Sbjct: 3507 EFECLALGDP--KPQVTWSKVGGHLRPGIVQ-------SGGVVRIAHVELADAGQYRCTA 3557
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ T+ V+L+V+ P++ + P V+ + G C P P +WSK
Sbjct: 3558 TNAAGT-TQSHVLLLVQALPQI-SMPQEVRVPA--GSAAVFPCIASGYPTPDISWSKLDG 3613
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
LP ++ + ++L++ +V D G+Y C A N G L V
Sbjct: 3614 SLPPDSRLE-------------NNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV-- 3658
Query: 457 APDQVV 462
P++VV
Sbjct: 3659 -PERVV 3663
Score = 47.2 bits (107), Expect = 2e-04
Identities = 59/232 (25%), Positives = 91/232 (39%), Gaps = 36/232 (15%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--------PAGIKSVSQNVV 271
+ GS+L + ++T D+G Y C V + G A++ V++ P I+S S V
Sbjct: 2198 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2257
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGN 331
D LSC G + W ++G S+ + S L I +A + G
Sbjct: 2258 EGQTLD--LSCVVAGQ--AHAQVTWYKRG-----GSLPARHQVRGSRLYIFQASPADAGQ 2308
Query: 332 FQCVVNNGIGSA---TKQDVMLIVKFKPEMDTSPNFVK-SASNV--GQVGRLMCKCKSVP 385
+ C +NG+ ++ T P T P ++ S+S V GQ L C
Sbjct: 2309 YVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQS 2368
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
TW K G LPV H T+ S+L + + +D G Y C
Sbjct: 2369 HAQVTWHKRGGSLPVR-------------HQTHGSLLRLYQASPADSGEYVC 2407
Score = 46.4 bits (105), Expect = 4e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 23/245 (9%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV-ANISVSVHYPAG---------IKSVSQN 269
+ GS L + ++ D+G Y C A + G A+ +V+V G I +
Sbjct: 2971 THGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPS 3030
Query: 270 VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENL 329
+DA C I + ++W+ + +++ +V P S + I + N
Sbjct: 3031 STVQQGQDASFKCL-IHDGAAPISLEWKTRNQELED-NVHISPNG--SIITIVGTRPSNH 3086
Query: 330 GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
G ++CV +N G A + V L V P + P VG+ L C P S
Sbjct: 3087 GTYRCVASNAYGVA-QSVVNLSVHGPPTVSVLPEGPVWVK-VGKAVTLECVSAGEPRSSA 3144
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
W++ P + + + +VL I++ SD G+Y C A+N LG +
Sbjct: 3145 RWTRIS-STPAKLEQRTYGLMDSH------AVLQISSAKPSDAGTYVCLAQNALGTAQKQ 3197
Query: 450 VKLDV 454
V++ V
Sbjct: 3198 VEVIV 3202
Score = 45.6 bits (103), Expect = 7e-04
Identities = 90/400 (22%), Positives = 147/400 (36%), Gaps = 54/400 (13%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
V AE + LT + A RC AT S T+ + +P + R E D L P +
Sbjct: 3214 VQAEEAELTVEAGHTATLRCSATGSPAP-----TIHWSKLRSPLPWQHRLEGDTLIIPRV 3268
Query: 135 ----EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADG 190
IC++ S PA + + V++ P + +V E + + A G
Sbjct: 3269 AQQDSGQYICNATS---PAGHAEATIILHVESPPYATTVPEHASVQA-GETVQLQCLAHG 3324
Query: 191 NPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV 250
PP +T+ W++ G SS R + +L+ + D+G Y C N G+A
Sbjct: 3325 TPP-LTFQWSRVG--------SSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAE 3375
Query: 251 ANISVSVHYPAG-IKSVSQNVVANPNEDAV--LSCTAIGNPL---------LAEHIKWER 298
A + V P G + + S + P L +IG + ++W +
Sbjct: 3376 AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDQGTQLRWFK 3435
Query: 299 KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
+G ++ P + L I+ G + C + G A + L+++ P +
Sbjct: 3436 EGGQLPPGHSVQD-----GVLRIQNLDQSCQGTYICQAHGPWGKA-QASAQLVIQALPSV 3489
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
+ VG C P P TWSK G L + +
Sbjct: 3490 LINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL-------------RPGIVQS 3536
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V+ I +V +D G Y C A N G + + V L V + P
Sbjct: 3537 GGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALP 3576
Score = 44.0 bits (99), Expect = 0.002
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 9/145 (6%)
Query: 13 MINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT 72
++++ + P AP + T+ AG L C +T G+P T+ W K+ S
Sbjct: 3201 IVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSAT-GSPAPTIHW----SKLRSPLPWQ 3255
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+ + I + QY C AT+ A T+ L+V P A V V +
Sbjct: 3256 HRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE--ATIILHVESPPYATTVPEHASV-QA 3312
Query: 133 GIEATLICDSASSNPPATLSWWRDG 157
G L C A PP T W R G
Sbjct: 3313 GETVQLQC-LAHGTPPLTFQWSRVG 3336
Score = 40.7 bits (91), Expect = 0.021
Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
I+ G ++ + + DAG Y C A N+ G +++ + V I S+ Q V
Sbjct: 3533 IVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQI-SMPQEVRVPAGSA 3591
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
AV C A G P I W + + P S + + L++ + ++ G + C
Sbjct: 3592 AVFPCIASGYP--TPDISWSKLDGSLPPDS-----RLENNMLMLPSVRPQDAGTYVCTAT 3644
Query: 338 NGIG 341
N G
Sbjct: 3645 NRQG 3648
Score = 37.9 bits (84), Expect = 0.15
Identities = 57/248 (22%), Positives = 89/248 (35%), Gaps = 45/248 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANI--------SVSVHYPA-------GIK 264
+ GS L + ++ D+G Y C + S G A++ S +VH PA I+
Sbjct: 2773 TRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIE 2832
Query: 265 SVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKA 324
S V D L C G + W ++G + + P L + +
Sbjct: 2833 PSSSRVAEGQTLD--LKCVVPGQ--AHAQVTWHKRGGNLPARHQVHGP-----LLRLNQV 2883
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK------SASNV--GQVGR 376
+ G + C V G+ ++ I P +P + S+S+V GQ
Sbjct: 2884 SPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLD 2943
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C TW K G LP H T+ S L ++ V+ +D G Y
Sbjct: 2944 LNCVVPGQAHAQVTWYKRGGSLPAR-------------HQTHGSQLRLHLVSPADSGEYV 2990
Query: 437 CGARNELG 444
C A + G
Sbjct: 2991 CRAASGPG 2998
Score = 37.1 bits (82), Expect = 0.26
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 356 PEMDTSPNFVK---SASNVGQVGR--LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
PE + +P V+ + S V Q G L C+ P F WS+ + PV + T+ +
Sbjct: 1670 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGR-PVPSGTQ---QR 1725
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTV 466
H+ + + SV SD G Y C RN +T+ +L VT AP + +++TV
Sbjct: 1726 HQGSELHFPSV------QPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTV 1775
Score = 35.5 bits (78), Expect = 0.79
Identities = 76/327 (23%), Positives = 119/327 (36%), Gaps = 56/327 (17%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+P + PI +++S V E + L ++ P +I TW K G S R
Sbjct: 2625 VPSVSPPIRIESSSPTVV--EGQTLDLNCVVARQPQAII-TWYKRG--------GSLPSR 2673
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKS 265
+ GS L + +++ D+G Y C A N+ A A+I +SV AG I+S
Sbjct: 2674 HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIES 2733
Query: 266 VSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAK 325
S +V D L+C G + W ++G S+ + S L +
Sbjct: 2734 SSSHVAEGETLD--LNCVVPGQ--AHAQVTWHKRG-----GSLPSHHQTRGSRLRLHHVS 2784
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLI------VKFKPEMDTSP--NFVKSASNV--GQVG 375
+ G + C V G ++ I P +P S+S V GQ
Sbjct: 2785 PADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTL 2844
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
L C TW K G LP H + +L +N V+ +D G Y
Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNLPAR-------------HQVHGPLLRLNQVSPADSGEY 2891
Query: 436 ECGARNELGFSTTTVKLDV-TSAPDQV 461
C G +V + + S+P +
Sbjct: 2892 SCQVTGSSGTLEASVLVTIEPSSPGPI 2918
Score = 35.1 bits (77), Expect = 1.0
Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 8/89 (8%)
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P++ T P AS GQ C VP P W N +P + +E +
Sbjct: 406 PQVVTPPRESIQASR-GQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG-- 462
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELG 444
L+I +V SD G+Y C A N G
Sbjct: 463 -----TLIIRDVKESDQGAYTCEAMNARG 486
Score = 33.5 bits (73), Expect = 3.2
Identities = 58/253 (22%), Positives = 95/253 (37%), Gaps = 48/253 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKSVS 267
+ GS+L + + + D+G Y C + S A++ V++ PAG I+S S
Sbjct: 2387 THGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVPALGVTPTVRIESSS 2445
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V D L+C G + W ++G + + S L + +
Sbjct: 2446 SQVAEGQTLD--LNCLVAGQ--AHAQVTWHKRGGSLPARHQVH-----GSRLRLLQVTPA 2496
Query: 328 NLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS-------PNFVKSASNV---GQVGRL 377
+ G + C V +GS+ Q+ ++V + + S P ++S+S G L
Sbjct: 2497 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2553
Query: 378 MCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
C S + TW K G LP + H S L I V +D G Y C
Sbjct: 2554 NCLVASQAPHTITWYKRGGSLP-------------SRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 438 GARNELGFSTTTV 450
N G T++
Sbjct: 2601 HVSNGAGSRETSL 2613
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 75.4 bits (177), Expect = 8e-13
Identities = 96/415 (23%), Positives = 170/415 (40%), Gaps = 38/415 (9%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTK--DGLPITQSSYSSGNDRIISEGSMLNMTKL 230
N V IE + ++ G PP ++TW + + + + YS + GS L ++ +
Sbjct: 248 NVVAIEGKDAVLECCVSGYPPP-SFTWLRGEEVIQLRSKKYS------LLGGSNLLISNV 300
Query: 231 TRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLL 290
T D+G+YTC A+ ++V P + N+ A + D CT G P+
Sbjct: 301 TDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPV- 359
Query: 291 AEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVML 350
+ W + G + P S F+ ++ I+ KS+ G +QCV N G+A + L
Sbjct: 360 -PTVNWMKNGDVVIP-SDYFQIVGGSNLRILGVVKSDE-GFYQCVAENEAGNA-QTSAQL 415
Query: 351 IVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG-VKLPVNTSTKYFAE 409
IV KP + +S + + SA V ++ + V +W K + T T +F+
Sbjct: 416 IVP-KPAIPSS-SVLPSAPR--DVVPVLVSSRFV---RLSWRPPAEAKGNIQTFTVFFSR 468
Query: 410 FHKNDHITYTSV------LLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPD---- 459
N + L + N+ ++ A NE G ++ + V + P+
Sbjct: 469 EGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVP 528
Query: 460 -QVVSLTVTNVTHSTVTLEW-VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTV 517
V +L + + +++ + W P + G YR+ +V S E + ++ +
Sbjct: 529 GPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTEV---STGKEQNIEVDGLSYKL 585
Query: 518 HGLEKNTDYIFSVMAINKIGQSKYRPDDTKATTLTSSEVGELSTVSTEYVETPDI 572
GL+K T+Y +A N+ G DD TL+ VS E V + I
Sbjct: 586 EGLKKFTEYSLRFLAYNRYGPG-VSTDDITVVTLSDVPSAPPQNVSLEVVNSRSI 639
Score = 72.5 bits (170), Expect = 6e-12
Identities = 75/270 (27%), Positives = 116/270 (42%), Gaps = 26/270 (9%)
Query: 179 NEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKL-TRH---D 234
N L S +D P I W KDG+ + + +S GS+L L +RH D
Sbjct: 56 NVLLDCSAESDRGVPVIK--WKKDGIHLALGM--DERKQQLSNGSLLIQNILHSRHHKPD 111
Query: 235 AGIYTCEA-VNSQGAAVANIS-VSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAE 292
G+Y CEA + G+ ++ + V+V P S +++V A + +L C IG P+
Sbjct: 112 EGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTI 171
Query: 293 HIKWERKGYKIDPKSVTFEPKNLTS-YLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLI 351
H W++ + P L S L I + + ++G ++C N S T + +
Sbjct: 172 H--WQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVR 229
Query: 352 VKFKPEMDTSPNFVKSASNV----GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYF 407
+ P + F++ SNV G+ L C P PSFTW + G ++ S KY
Sbjct: 230 ILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKY- 287
Query: 408 AEFHKNDHITYTSVLLINNVATSDYGSYEC 437
+ S LLI+NV D G Y C
Sbjct: 288 -------SLLGGSNLLISNVTDDDSGMYTC 310
Score = 66.9 bits (156), Expect = 3e-10
Identities = 95/369 (25%), Positives = 146/369 (39%), Gaps = 50/369 (13%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGS-MLNMTKLTRHDAGIYTCEAVNSQGAAVA 251
P T W K+ +T G+ R++ S L +++L D GIY C A N +
Sbjct: 167 PMPTIHWQKNQQDLTPIP---GDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTG 223
Query: 252 NISV-------SVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKID 304
N + +H NVVA +DAVL C G P W R I
Sbjct: 224 NEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYP--PPSFTWLRGEEVIQ 281
Query: 305 PKSVTFEPKNLTSYLIIRKAKSENLGNFQCVV---NNGIGSATKQDVMLIVKFKPEMDTS 361
+S + S L+I ++ G + CVV N I ++ + V++ P
Sbjct: 282 LRSKKYSLLG-GSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLV----PPWFLNH 336
Query: 362 PNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSV 421
P+ + + ++ C P P+ W KNG V + YF I S
Sbjct: 337 PSNLYAYESMDI--EFECTVSGKPVPTVNWMKNG---DVVIPSDYF-------QIVGGSN 384
Query: 422 LLINNVATSDYGSYECGARNELGFSTTTVKLDV-----------TSAPDQVVSLTVTNVT 470
L I V SD G Y+C A NE G + T+ +L V SAP VV + V++
Sbjct: 385 LRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSS-- 442
Query: 471 HSTVTLEWVPGFD--GGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIF 528
V L W P + G +Q+ + + + + D+ + + + TV L+ Y F
Sbjct: 443 -RFVRLSWRPPAEAKGNIQT-FTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTF 500
Query: 529 SVMAINKIG 537
V+A N+ G
Sbjct: 501 RVVAYNEWG 509
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 75.4 bits (177), Expect = 8e-13
Identities = 91/383 (23%), Positives = 163/383 (42%), Gaps = 31/383 (8%)
Query: 175 VGIENEPLIISVRADGNP-PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRH 233
V + + +++ A G P P+I + ++ L T+SS ++ G L ++ +T
Sbjct: 259 VRVIGQDVVLPCVASGLPTPTIKWMKNEEALD-TESS----ERLVLLAGGSLEISDVTED 313
Query: 234 DAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
DAG Y C A N A ++V N+ A+ + D V C G P
Sbjct: 314 DAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKP--TPT 371
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+KW + G + P S F+ + ++ KS+ G +QC+ N +G+A ++I++
Sbjct: 372 VKWVKNGDMVIP-SDYFKIVKEHNLQVLGLVKSDE-GFYQCIAENDVGNAQAGAQLIILE 429
Query: 354 FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKN 413
P T P + SA V + + + T + + + S Y E
Sbjct: 430 HAP-ATTGP--LPSAPR--DVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIAR 484
Query: 414 DHITYTS-----VLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTVTN 468
+ + TS + I N+ + + A+N+ G ++ L V + P+ + N
Sbjct: 485 ERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPN 544
Query: 469 V-------THSTVTLEWVPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATNFTVHGLE 521
+ T TVT E +G +Q+ Y++ Y + D + DV + ++T++GL+
Sbjct: 545 LRAYAASPTSITVTWETPVSGNGEIQN-YKLYYMEKGTDKEQDVDV---SSHSYTINGLK 600
Query: 522 KNTDYIFSVMAINKIGQSKYRPD 544
K T+Y F V+A NK G PD
Sbjct: 601 KYTEYSFRVVAYNKHGPGVSTPD 623
Score = 65.3 bits (152), Expect = 9e-10
Identities = 88/348 (25%), Positives = 138/348 (39%), Gaps = 41/348 (11%)
Query: 215 NDRIISEGS-MLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNV-VA 272
+DR+I S ML ++ T D G+Y C V S G + V + + +S V +
Sbjct: 195 DDRVIKLPSGMLVISNATEGDGGLYRC-VVESGGPPKYSDEVELKVLPDPEVISDLVFLK 253
Query: 273 NPN-------EDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAK 325
P+ +D VL C A G P IKW + +D +S L I
Sbjct: 254 QPSPLVRVIGQDVVLPCVASGLP--TPTIKWMKNEEALDTESSERLVLLAGGSLEISDVT 311
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVP 385
++ G + C+ +NG + L V+ +PE P + + ++ V C+ P
Sbjct: 312 EDDAGTYFCIADNG-NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV--FECEVTGKP 368
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGF 445
P+ W KNG + + YF +++ L + + SD G Y+C A N++G
Sbjct: 369 TPTVKWVKNGDMV---IPSDYFKIVKEHN-------LQVLGLVKSDEGFYQCIAENDVGN 418
Query: 446 STTTVKLDVT-----------SAPDQVVSLTVTNVTHSTVTLEW-VPGFDG-GLQSWYRI 492
+ +L + SAP VV+ V+ + L W P D G Y +
Sbjct: 419 AQAGAQLIILEHAPATTGPLPSAPRDVVASLVST---RFIKLTWRTPASDPHGDNLTYSV 475
Query: 493 RYRKVFDDSYKYEDVLPKHATNFTVHGLEKNTDYIFSVMAINKIGQSK 540
Y K + E+ T+ L T YIF VMA NK G +
Sbjct: 476 FYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGE 523
Score = 64.1 bits (149), Expect = 2e-09
Identities = 92/386 (23%), Positives = 165/386 (42%), Gaps = 44/386 (11%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSML--NM--T 228
+T+ + +I++ A P S W KDG + + S +++ +GS+ N+ +
Sbjct: 61 DTLSVRGSSVILNCSAYSEP-SPKIEWKKDGTFL--NLVSDDRRQLLPDGSLFISNVVHS 117
Query: 229 KLTRHDAGIYTCEA-VNSQGAAVANISVSVHYPAGI-KSVSQNVVAN--PNEDAVLSCTA 284
K + D G Y C A V S G ++ + + AG+ + SQ ++ +A+L+C
Sbjct: 118 KHNKPDEGYYQCVATVESLGTIISRTAKLI--VAGLPRFTSQPEPSSVYAGNNAILNCEV 175
Query: 285 IGNPLLAEHIKWE--RKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGS 342
N L ++WE R+ +D + + P + L+I A + G ++CVV +G
Sbjct: 176 --NADLVPFVRWEQNRQPLLLDDRVIKL-PSGM---LVISNATEGDGGLYRCVVESGGPP 229
Query: 343 ATKQDVMLIVKFKPEMDTSPNFVKSASN----VGQVGRLMCKCKSVPAPSFTWSKNGVKL 398
+V L V PE+ + F+K S +GQ L C +P P+ W KN L
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289
Query: 399 PVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
+S + + L I++V D G+Y C A N G T + ++T
Sbjct: 290 DTESSERLV--------LLAGGSLEISDVTEDDAGTYFCIADN--GNETIEAQAELTVQA 339
Query: 459 DQVVSLTVTNV-THSTVTLEW---VPGFDGGLQSWYRIRYRKVFDDSYKYEDVLPKHATN 514
TN+ H ++ + + V G W + + D +K ++ +H N
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFK---IVKEH--N 394
Query: 515 FTVHGLEKNTDYIFSVMAINKIGQSK 540
V GL K+ + + +A N +G ++
Sbjct: 395 LQVLGLVKSDEGFYQCIAENDVGNAQ 420
Score = 47.6 bits (108), Expect = 2e-04
Identities = 93/388 (23%), Positives = 150/388 (38%), Gaps = 51/388 (13%)
Query: 173 NTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTR 232
N E+ ++ G P T W K+G + S Y +I+ E + L + L +
Sbjct: 349 NIYAHESMDIVFECEVTGKPTP-TVKWVKNGDMVIPSDYF----KIVKEHN-LQVLGLVK 402
Query: 233 HDAGIYTCEAVNSQGAAVANISVSV--HYPAG---IKSVSQNVVANPNEDAVLSCT---A 284
D G Y C A N G A A + + H PA + S ++VVA+ + T
Sbjct: 403 SDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTP 462
Query: 285 IGNPL---LAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG 341
+P L + + ++G + T P + + I+ + F+ + N G
Sbjct: 463 ASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQ--VTIQNLMPATVYIFRVMAQNKHG 520
Query: 342 SATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTW----SKNGVK 397
S + L V+ +PE+ G L S + + TW S NG
Sbjct: 521 SG-ESSAPLRVETQPEVQLP----------GPAPNLRAYAASPTSITVTWETPVSGNG-- 567
Query: 398 LPVNTSTKYFAE--FHKNDHITYTS-VLLINNVATSDYGSYECGARNELG--FSTTTVKL 452
+ Y+ E K + +S IN + S+ A N+ G ST V +
Sbjct: 568 -EIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAV 626
Query: 453 ----DVTSAPDQVVSLTVTNVTHSTVTLEW---VPGFDGGLQSWYRIRYRKVFDDSYKYE 505
DV SA Q +SL V N ++ + W P G + Y+IRYRK S E
Sbjct: 627 RTLSDVPSAAPQNLSLEVRN--SKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTE 684
Query: 506 DVLPKHATNFTVHGLEKNTDYIFSVMAI 533
++ + + GL++ T+Y F V A+
Sbjct: 685 TLVSGTQLSQLIEGLDRGTEYNFRVAAL 712
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 75.4 bits (177), Expect = 8e-13
Identities = 66/258 (25%), Positives = 101/258 (39%), Gaps = 22/258 (8%)
Query: 207 TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSV 266
T++ N I GS++ + + G Y C A N+ G A + +++SVH P + +
Sbjct: 3058 TRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVL 3117
Query: 267 SQNVV-ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKA 324
+ V + L C + G P +W R + T+ + + L I A
Sbjct: 3118 PEGPVWVKVGKAVTLECVSAGEP--RSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSA 3175
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCK 380
K + G + C+ N +G+A KQ V +IV +P + + G L C
Sbjct: 3176 KPSDAGTYVCLAQNALGTAQKQ-VEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCS 3234
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
PAP+ WSK LP H L+I VA D G Y C A
Sbjct: 3235 ATGSPAPTIHWSKLRSPLPW-------------QHRLEGDTLIIPRVAQQDSGQYICNAT 3281
Query: 441 NELGFSTTTVKLDVTSAP 458
+ G + T+ L V S P
Sbjct: 3282 SPAGHAEATIILHVESPP 3299
Score = 65.3 bits (152), Expect = 9e-10
Identities = 61/246 (24%), Positives = 105/246 (42%), Gaps = 13/246 (5%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVL 280
EG L + ++ + D+G Y C A + G A A I + V P +V ++ E L
Sbjct: 3259 EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL 3318
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
C A G P L +W R G + ++ +N L +A E+ G ++C V N +
Sbjct: 3319 QCLAHGTPPLT--FQWSRVGSSLPGRATA---RN--ELLHFERAAPEDSGRYRCRVTNKV 3371
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV 400
GSA + L+V+ P + + ++ QV + + KS+ A V
Sbjct: 3372 GSA-EAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQL-ETKSIGAS--VEFHCAVPSDR 3427
Query: 401 NTSTKYFAEFHK--NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T ++F E + H VL I N+ S G+Y C A G + + +L + + P
Sbjct: 3428 GTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALP 3487
Query: 459 DQVVSL 464
++++
Sbjct: 3488 SVLINI 3493
Score = 57.2 bits (132), Expect = 2e-07
Identities = 59/250 (23%), Positives = 101/250 (40%), Gaps = 26/250 (10%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVN----SQGAAVANISVSVHYPAGIKSVSQ-NVV 271
R + +L + + DAG Y C N QG A ++ S A + S+ +
Sbjct: 1817 RAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1876
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLG 330
P + A C+A G+P ++W G ++ K+ L + + +
Sbjct: 1877 VQPGQLAEFRCSATGSP--TPTLEWTGGPGGQLPAKAQIHG-----GILRLPAVEPTDQA 1929
Query: 331 NFQCVVNNGIGSATKQDVMLIVKFK-PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
+ C ++ G + V+ + P + SP ++ + G+ RL C+ VP+ +
Sbjct: 1930 QYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPE--RTQVHAGRTVRLYCRAAGVPSATI 1987
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
TW K G LP A + D T LLI + T+D G Y C A + G +
Sbjct: 1988 TWRKEGGSLPPQ------ARSERTDIAT----LLIPAITTADAGFYLCVATSPAGTAQAR 2037
Query: 450 VKLDVTSAPD 459
+++ V SA D
Sbjct: 2038 IQVVVLSASD 2047
Score = 56.4 bits (130), Expect = 4e-07
Identities = 99/480 (20%), Positives = 177/480 (36%), Gaps = 68/480 (14%)
Query: 23 APMITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP++ P ++ G L C G+P W + D + + T + +E+
Sbjct: 1675 APLVVEVHPARSIVPQGGSHSLRC-QVSGSPPHYFYWSREDGR-PVPSGTQQRHQGSELH 1732
Query: 82 ILTNVTDNQAQYRCEATN-SATEIPLFETVTLNVHFAPEAVKVRAE-PDVLKPGIEATLI 139
+ + Y C N + E + P V V + ++PG + T I
Sbjct: 1733 FPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFI 1792
Query: 140 CDSASSNPPATLSWWR-------------DGI-PVQNAPIFDD----TTSYNTVGIENEP 181
C + S +P TL W R +GI ++N + D T N ++
Sbjct: 1793 CTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGT 1852
Query: 182 LIISVRADG---------NPPSIT--------YTWTKDGLPITQSSYSSGNDRIIS---- 220
+ V+A G +PP +T + + G P ++ G +
Sbjct: 1853 ATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQ 1912
Query: 221 -EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG--IKSVSQNVVANPNED 277
G +L + + D Y C A +S G VA + VH G ++ + +
Sbjct: 1913 IHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRT 1972
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
L C A G P + I W ++G + P++ + E ++ + L+I + + G + CV
Sbjct: 1973 VRLYCRAAGVP--SATITWRKEGGSLPPQARS-ERTDIAT-LLIPAITTADAGFYLCVAT 2028
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS---NVGQVGRLMCKCKSVPAPSFTWSKN 394
+ G+A + + ++V + P ++S+S GQ L C TW +
Sbjct: 2029 SPAGTAQAR-IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRR 2087
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
G LP +T + S L + V+ +D G Y C N G ++ + V
Sbjct: 2088 GGSLPPHTQ-------------VHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSV 2134
Score = 53.6 bits (123), Expect = 3e-06
Identities = 80/323 (24%), Positives = 119/323 (36%), Gaps = 49/323 (15%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS T TW K+G + + S D + L + +T DAG Y C A + G A A
Sbjct: 1983 PSATITWRKEGGSLPPQARSERTDI-----ATLLIPAITTADAGFYLCVATSPAGTAQAR 2037
Query: 253 ISVSV-----HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS 307
I V V P +K S + + L+C G+ + W R+G + P +
Sbjct: 2038 IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGS--AHAQVTWYRRGGSLPPHT 2095
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG---SATKQDVMLIVKFKPEMDTSPNF 364
S L + + + G + C V NG G ++ V+ P P
Sbjct: 2096 QVH-----GSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGS 2150
Query: 365 VK------SASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ S+S+V GQ L C TW K G LP H
Sbjct: 2151 TRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPAR-------------HQ 2197
Query: 417 TYTSVLLINNVATSDYGSYEC---GARNELGFST-TTVKLDVTSA---PDQVVSLTVTNV 469
T+ S+L ++ V +D G Y C G L S T++ V P ++ S + T
Sbjct: 2198 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2257
Query: 470 THSTVTLEWVPGFDGGLQ-SWYR 491
T+ L V Q +WY+
Sbjct: 2258 EGQTLDLSCVVAGQAHAQVTWYK 2280
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/253 (24%), Positives = 100/253 (39%), Gaps = 42/253 (16%)
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH------------YPAGIKSVSQN 269
GS L + ++T D+G Y C V S G A++ V++ YP I+S S +
Sbjct: 2485 GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSAS 2544
Query: 270 VVANPNEDAVLSCTAIGNPLLAEH-IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
+ D L+C A H I W ++G S+ + + S L I + +
Sbjct: 2545 LANGHTLD--LNCLVASQ---APHTITWYKRG-----GSLPSRHQIVGSRLRIPQVTPAD 2594
Query: 329 LGNFQCVVNNGIGSATKQDVMLI----VKFKPEMDTSPNFVKSASNV--GQVGRLMCKCK 382
G + C V+NG GS ++ I P + S+ V GQ L C
Sbjct: 2595 SGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 2654
Query: 383 SVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNE 442
P TW K G LP + H T+ S L ++ ++ +D G Y C A N
Sbjct: 2655 RQPQAIITWYKRGGSLP-------------SRHQTHGSHLRLHQMSVADSGEYVCRANNN 2701
Query: 443 LGFSTTTVKLDVT 455
+ ++ + V+
Sbjct: 2702 IDALEASIVISVS 2714
Score = 52.4 bits (120), Expect = 6e-06
Identities = 59/246 (23%), Positives = 104/246 (42%), Gaps = 33/246 (13%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNEDAV 279
+ +L + L + G Y C+A G A A+ + + P+ + ++ +V AV
Sbjct: 3447 QDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAV 3506
Query: 280 -LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE--NLGNFQCVV 336
C A+G+P + W + G + P V S ++R A E + G ++C
Sbjct: 3507 EFECLALGDP--KPQVTWSKVGGHLRPGIVQ-------SGGVVRIAHVELADAGQYRCTA 3557
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ T+ V+L+V+ P++ + P V+ + G C P P +WSK
Sbjct: 3558 TNAAGT-TQSHVLLLVQALPQI-SMPQEVRVPA--GSAAVFPCIASGYPTPDISWSKLDG 3613
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
LP ++ + ++L++ +V D G+Y C A N G L V
Sbjct: 3614 SLPPDSRLE-------------NNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV-- 3658
Query: 457 APDQVV 462
P++VV
Sbjct: 3659 -PERVV 3663
Score = 47.2 bits (107), Expect = 2e-04
Identities = 59/232 (25%), Positives = 91/232 (39%), Gaps = 36/232 (15%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--------PAGIKSVSQNVV 271
+ GS+L + ++T D+G Y C V + G A++ V++ P I+S S V
Sbjct: 2198 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2257
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGN 331
D LSC G + W ++G S+ + S L I +A + G
Sbjct: 2258 EGQTLD--LSCVVAGQ--AHAQVTWYKRG-----GSLPARHQVRGSRLYIFQASPADAGQ 2308
Query: 332 FQCVVNNGIGSA---TKQDVMLIVKFKPEMDTSPNFVK-SASNV--GQVGRLMCKCKSVP 385
+ C +NG+ ++ T P T P ++ S+S V GQ L C
Sbjct: 2309 YVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQS 2368
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
TW K G LPV H T+ S+L + + +D G Y C
Sbjct: 2369 HAQVTWHKRGGSLPVR-------------HQTHGSLLRLYQASPADSGEYVC 2407
Score = 46.4 bits (105), Expect = 4e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 23/245 (9%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV-ANISVSVHYPAG---------IKSVSQN 269
+ GS L + ++ D+G Y C A + G A+ +V+V G I +
Sbjct: 2971 THGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPS 3030
Query: 270 VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENL 329
+DA C I + ++W+ + +++ +V P S + I + N
Sbjct: 3031 STVQQGQDASFKCL-IHDGAAPISLEWKTRNQELED-NVHISPNG--SIITIVGTRPSNH 3086
Query: 330 GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
G ++CV +N G A + V L V P + P VG+ L C P S
Sbjct: 3087 GTYRCVASNAYGVA-QSVVNLSVHGPPTVSVLPEGPVWVK-VGKAVTLECVSAGEPRSSA 3144
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
W++ P + + + +VL I++ SD G+Y C A+N LG +
Sbjct: 3145 RWTRIS-STPAKLEQRTYGLMDSH------AVLQISSAKPSDAGTYVCLAQNALGTAQKQ 3197
Query: 450 VKLDV 454
V++ V
Sbjct: 3198 VEVIV 3202
Score = 45.6 bits (103), Expect = 7e-04
Identities = 90/400 (22%), Positives = 147/400 (36%), Gaps = 54/400 (13%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
V AE + LT + A RC AT S T+ + +P + R E D L P +
Sbjct: 3214 VQAEEAELTVEAGHTATLRCSATGSPAP-----TIHWSKLRSPLPWQHRLEGDTLIIPRV 3268
Query: 135 ----EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADG 190
IC++ S PA + + V++ P + +V E + + A G
Sbjct: 3269 AQQDSGQYICNATS---PAGHAEATIILHVESPPYATTVPEHASVQA-GETVQLQCLAHG 3324
Query: 191 NPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV 250
PP +T+ W++ G SS R + +L+ + D+G Y C N G+A
Sbjct: 3325 TPP-LTFQWSRVG--------SSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAE 3375
Query: 251 ANISVSVHYPAG-IKSVSQNVVANPNEDAV--LSCTAIGNPL---------LAEHIKWER 298
A + V P G + + S + P L +IG + ++W +
Sbjct: 3376 AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFK 3435
Query: 299 KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
+G ++ P + L I+ G + C + G A + L+++ P +
Sbjct: 3436 EGGQLPPGHSVQD-----GVLRIQNLDQSCQGTYICQAHGPWGKA-QASAQLVIQALPSV 3489
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
+ VG C P P TWSK G L + +
Sbjct: 3490 LINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL-------------RPGIVQS 3536
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V+ I +V +D G Y C A N G + + V L V + P
Sbjct: 3537 GGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALP 3576
Score = 44.0 bits (99), Expect = 0.002
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 9/145 (6%)
Query: 13 MINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT 72
++++ + P AP + T+ AG L C +T G+P T+ W K+ S
Sbjct: 3201 IVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSAT-GSPAPTIHW----SKLRSPLPWQ 3255
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+ + I + QY C AT+ A T+ L+V P A V V +
Sbjct: 3256 HRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE--ATIILHVESPPYATTVPEHASV-QA 3312
Query: 133 GIEATLICDSASSNPPATLSWWRDG 157
G L C A PP T W R G
Sbjct: 3313 GETVQLQC-LAHGTPPLTFQWSRVG 3336
Score = 40.7 bits (91), Expect = 0.021
Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
I+ G ++ + + DAG Y C A N+ G +++ + V I S+ Q V
Sbjct: 3533 IVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQI-SMPQEVRVPAGSA 3591
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
AV C A G P I W + + P S + + L++ + ++ G + C
Sbjct: 3592 AVFPCIASGYP--TPDISWSKLDGSLPPDS-----RLENNMLMLPSVRPQDAGTYVCTAT 3644
Query: 338 NGIG 341
N G
Sbjct: 3645 NRQG 3648
Score = 37.9 bits (84), Expect = 0.15
Identities = 57/248 (22%), Positives = 89/248 (35%), Gaps = 45/248 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANI--------SVSVHYPA-------GIK 264
+ GS L + ++ D+G Y C + S G A++ S +VH PA I+
Sbjct: 2773 TRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIE 2832
Query: 265 SVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKA 324
S V D L C G + W ++G + + P L + +
Sbjct: 2833 PSSSRVAEGQTLD--LKCVVPGQ--AHAQVTWHKRGGNLPARHQVHGP-----LLRLNQV 2883
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK------SASNV--GQVGR 376
+ G + C V G+ ++ I P +P + S+S+V GQ
Sbjct: 2884 SPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLD 2943
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C TW K G LP H T+ S L ++ V+ +D G Y
Sbjct: 2944 LNCVVPGQAHAQVTWYKRGGSLPAR-------------HQTHGSQLRLHLVSPADSGEYV 2990
Query: 437 CGARNELG 444
C A + G
Sbjct: 2991 CRAASGPG 2998
Score = 37.1 bits (82), Expect = 0.26
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 356 PEMDTSPNFVK---SASNVGQVGR--LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
PE + +P V+ + S V Q G L C+ P F WS+ + PV + T+ +
Sbjct: 1670 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGR-PVPSGTQ---QR 1725
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTV 466
H+ + + SV SD G Y C RN +T+ +L VT AP + +++TV
Sbjct: 1726 HQGSELHFPSV------QPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTV 1775
Score = 35.5 bits (78), Expect = 0.79
Identities = 76/327 (23%), Positives = 119/327 (36%), Gaps = 56/327 (17%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+P + PI +++S V E + L ++ P +I TW K G S R
Sbjct: 2625 VPSVSPPIRIESSSPTVV--EGQTLDLNCVVARQPQAII-TWYKRG--------GSLPSR 2673
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKS 265
+ GS L + +++ D+G Y C A N+ A A+I +SV AG I+S
Sbjct: 2674 HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIES 2733
Query: 266 VSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAK 325
S +V D L+C G + W ++G S+ + S L +
Sbjct: 2734 SSSHVAEGETLD--LNCVVPGQ--AHAQVTWHKRG-----GSLPSHHQTRGSRLRLHHVS 2784
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLI------VKFKPEMDTSP--NFVKSASNV--GQVG 375
+ G + C V G ++ I P +P S+S V GQ
Sbjct: 2785 PADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTL 2844
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
L C TW K G LP H + +L +N V+ +D G Y
Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNLPAR-------------HQVHGPLLRLNQVSPADSGEY 2891
Query: 436 ECGARNELGFSTTTVKLDV-TSAPDQV 461
C G +V + + S+P +
Sbjct: 2892 SCQVTGSSGTLEASVLVTIEPSSPGPI 2918
Score = 35.1 bits (77), Expect = 1.0
Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 8/89 (8%)
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P++ T P AS GQ C VP P W N +P + +E +
Sbjct: 406 PQVVTPPRESIQASR-GQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG-- 462
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELG 444
L+I +V SD G+Y C A N G
Sbjct: 463 -----TLIIRDVKESDQGAYTCEAMNARG 486
Score = 33.5 bits (73), Expect = 3.2
Identities = 58/253 (22%), Positives = 95/253 (37%), Gaps = 48/253 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKSVS 267
+ GS+L + + + D+G Y C + S A++ V++ PAG I+S S
Sbjct: 2387 THGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVPALGVTPTVRIESSS 2445
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V D L+C G + W ++G + + S L + +
Sbjct: 2446 SQVAEGQTLD--LNCLVAGQ--AHAQVTWHKRGGSLPARHQVH-----GSRLRLLQVTPA 2496
Query: 328 NLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS-------PNFVKSASNV---GQVGRL 377
+ G + C V +GS+ Q+ ++V + + S P ++S+S G L
Sbjct: 2497 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2553
Query: 378 MCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
C S + TW K G LP + H S L I V +D G Y C
Sbjct: 2554 NCLVASQAPHTITWYKRGGSLP-------------SRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 438 GARNELGFSTTTV 450
N G T++
Sbjct: 2601 HVSNGAGSRETSL 2613
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 75.4 bits (177), Expect = 8e-13
Identities = 66/258 (25%), Positives = 101/258 (39%), Gaps = 22/258 (8%)
Query: 207 TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSV 266
T++ N I GS++ + + G Y C A N+ G A + +++SVH P + +
Sbjct: 3058 TRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVL 3117
Query: 267 SQNVV-ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKA 324
+ V + L C + G P +W R + T+ + + L I A
Sbjct: 3118 PEGPVWVKVGKAVTLECVSAGEP--RSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSA 3175
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCK 380
K + G + C+ N +G+A KQ V +IV +P + + G L C
Sbjct: 3176 KPSDAGTYVCLAQNALGTAQKQ-VEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCS 3234
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
PAP+ WSK LP H L+I VA D G Y C A
Sbjct: 3235 ATGSPAPTIHWSKLRSPLPW-------------QHRLEGDTLIIPRVAQQDSGQYICNAT 3281
Query: 441 NELGFSTTTVKLDVTSAP 458
+ G + T+ L V S P
Sbjct: 3282 SPAGHAEATIILHVESPP 3299
Score = 65.3 bits (152), Expect = 9e-10
Identities = 61/246 (24%), Positives = 105/246 (42%), Gaps = 13/246 (5%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVL 280
EG L + ++ + D+G Y C A + G A A I + V P +V ++ E L
Sbjct: 3259 EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL 3318
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
C A G P L +W R G + ++ +N L +A E+ G ++C V N +
Sbjct: 3319 QCLAHGTPPLT--FQWSRVGSSLPGRATA---RN--ELLHFERAAPEDSGRYRCRVTNKV 3371
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV 400
GSA + L+V+ P + + ++ QV + + KS+ A V
Sbjct: 3372 GSA-EAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQL-ETKSIGAS--VEFHCAVPSDR 3427
Query: 401 NTSTKYFAEFHK--NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T ++F E + H VL I N+ S G+Y C A G + + +L + + P
Sbjct: 3428 GTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALP 3487
Query: 459 DQVVSL 464
++++
Sbjct: 3488 SVLINI 3493
Score = 57.2 bits (132), Expect = 2e-07
Identities = 59/250 (23%), Positives = 101/250 (40%), Gaps = 26/250 (10%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVN----SQGAAVANISVSVHYPAGIKSVSQ-NVV 271
R + +L + + DAG Y C N QG A ++ S A + S+ +
Sbjct: 1817 RAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1876
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLG 330
P + A C+A G+P ++W G ++ K+ L + + +
Sbjct: 1877 VQPGQLAEFRCSATGSP--TPTLEWTGGPGGQLPAKAQIHG-----GILRLPAVEPTDQA 1929
Query: 331 NFQCVVNNGIGSATKQDVMLIVKFK-PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
+ C ++ G + V+ + P + SP ++ + G+ RL C+ VP+ +
Sbjct: 1930 QYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPE--RTQVHAGRTVRLYCRAAGVPSATI 1987
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
TW K G LP A + D T LLI + T+D G Y C A + G +
Sbjct: 1988 TWRKEGGSLPPQ------ARSERTDIAT----LLIPAITTADAGFYLCVATSPAGTAQAR 2037
Query: 450 VKLDVTSAPD 459
+++ V SA D
Sbjct: 2038 IQVVVLSASD 2047
Score = 56.4 bits (130), Expect = 4e-07
Identities = 99/480 (20%), Positives = 177/480 (36%), Gaps = 68/480 (14%)
Query: 23 APMITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP++ P ++ G L C G+P W + D + + T + +E+
Sbjct: 1675 APLVVEVHPARSIVPQGGSHSLRC-QVSGSPPHYFYWSREDGR-PVPSGTQQRHQGSELH 1732
Query: 82 ILTNVTDNQAQYRCEATN-SATEIPLFETVTLNVHFAPEAVKVRAE-PDVLKPGIEATLI 139
+ + Y C N + E + P V V + ++PG + T I
Sbjct: 1733 FPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFI 1792
Query: 140 CDSASSNPPATLSWWR-------------DGI-PVQNAPIFDD----TTSYNTVGIENEP 181
C + S +P TL W R +GI ++N + D T N ++
Sbjct: 1793 CTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGT 1852
Query: 182 LIISVRADG---------NPPSIT--------YTWTKDGLPITQSSYSSGNDRIIS---- 220
+ V+A G +PP +T + + G P ++ G +
Sbjct: 1853 ATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQ 1912
Query: 221 -EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG--IKSVSQNVVANPNED 277
G +L + + D Y C A +S G VA + VH G ++ + +
Sbjct: 1913 IHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRT 1972
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
L C A G P + I W ++G + P++ + E ++ + L+I + + G + CV
Sbjct: 1973 VRLYCRAAGVP--SATITWRKEGGSLPPQARS-ERTDIAT-LLIPAITTADAGFYLCVAT 2028
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS---NVGQVGRLMCKCKSVPAPSFTWSKN 394
+ G+A + + ++V + P ++S+S GQ L C TW +
Sbjct: 2029 SPAGTAQAR-IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRR 2087
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
G LP +T + S L + V+ +D G Y C N G ++ + V
Sbjct: 2088 GGSLPPHTQ-------------VHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSV 2134
Score = 53.6 bits (123), Expect = 3e-06
Identities = 80/323 (24%), Positives = 119/323 (36%), Gaps = 49/323 (15%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS T TW K+G + + S D + L + +T DAG Y C A + G A A
Sbjct: 1983 PSATITWRKEGGSLPPQARSERTDI-----ATLLIPAITTADAGFYLCVATSPAGTAQAR 2037
Query: 253 ISVSV-----HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS 307
I V V P +K S + + L+C G+ + W R+G + P +
Sbjct: 2038 IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGS--AHAQVTWYRRGGSLPPHT 2095
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG---SATKQDVMLIVKFKPEMDTSPNF 364
S L + + + G + C V NG G ++ V+ P P
Sbjct: 2096 QVH-----GSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGS 2150
Query: 365 VK------SASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ S+S+V GQ L C TW K G LP H
Sbjct: 2151 TRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPAR-------------HQ 2197
Query: 417 TYTSVLLINNVATSDYGSYEC---GARNELGFST-TTVKLDVTSA---PDQVVSLTVTNV 469
T+ S+L ++ V +D G Y C G L S T++ V P ++ S + T
Sbjct: 2198 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2257
Query: 470 THSTVTLEWVPGFDGGLQ-SWYR 491
T+ L V Q +WY+
Sbjct: 2258 EGQTLDLSCVVAGQAHAQVTWYK 2280
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/253 (24%), Positives = 100/253 (39%), Gaps = 42/253 (16%)
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH------------YPAGIKSVSQN 269
GS L + ++T D+G Y C V S G A++ V++ YP I+S S +
Sbjct: 2485 GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSAS 2544
Query: 270 VVANPNEDAVLSCTAIGNPLLAEH-IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
+ D L+C A H I W ++G S+ + + S L I + +
Sbjct: 2545 LANGHTLD--LNCLVASQ---APHTITWYKRG-----GSLPSRHQIVGSRLRIPQVTPAD 2594
Query: 329 LGNFQCVVNNGIGSATKQDVMLI----VKFKPEMDTSPNFVKSASNV--GQVGRLMCKCK 382
G + C V+NG GS ++ I P + S+ V GQ L C
Sbjct: 2595 SGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 2654
Query: 383 SVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNE 442
P TW K G LP + H T+ S L ++ ++ +D G Y C A N
Sbjct: 2655 RQPQAIITWYKRGGSLP-------------SRHQTHGSHLRLHQMSVADSGEYVCRANNN 2701
Query: 443 LGFSTTTVKLDVT 455
+ ++ + V+
Sbjct: 2702 IDALEASIVISVS 2714
Score = 52.4 bits (120), Expect = 6e-06
Identities = 59/246 (23%), Positives = 104/246 (42%), Gaps = 33/246 (13%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNEDAV 279
+ +L + L + G Y C+A G A A+ + + P+ + ++ +V AV
Sbjct: 3447 QDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAV 3506
Query: 280 -LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE--NLGNFQCVV 336
C A+G+P + W + G + P V S ++R A E + G ++C
Sbjct: 3507 EFECLALGDP--KPQVTWSKVGGHLRPGIVQ-------SGGVVRIAHVELADAGQYRCTA 3557
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ T+ V+L+V+ P++ + P V+ + G C P P +WSK
Sbjct: 3558 TNAAGT-TQSHVLLLVQALPQI-SMPQEVRVPA--GSAAVFPCIASGYPTPDISWSKLDG 3613
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
LP ++ + ++L++ +V D G+Y C A N G L V
Sbjct: 3614 SLPPDSRLE-------------NNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV-- 3658
Query: 457 APDQVV 462
P++VV
Sbjct: 3659 -PERVV 3663
Score = 47.2 bits (107), Expect = 2e-04
Identities = 59/232 (25%), Positives = 91/232 (39%), Gaps = 36/232 (15%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--------PAGIKSVSQNVV 271
+ GS+L + ++T D+G Y C V + G A++ V++ P I+S S V
Sbjct: 2198 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2257
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGN 331
D LSC G + W ++G S+ + S L I +A + G
Sbjct: 2258 EGQTLD--LSCVVAGQ--AHAQVTWYKRG-----GSLPARHQVRGSRLYIFQASPADAGQ 2308
Query: 332 FQCVVNNGIGSA---TKQDVMLIVKFKPEMDTSPNFVK-SASNV--GQVGRLMCKCKSVP 385
+ C +NG+ ++ T P T P ++ S+S V GQ L C
Sbjct: 2309 YVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQS 2368
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
TW K G LPV H T+ S+L + + +D G Y C
Sbjct: 2369 HAQVTWHKRGGSLPVR-------------HQTHGSLLRLYQASPADSGEYVC 2407
Score = 46.4 bits (105), Expect = 4e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 23/245 (9%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV-ANISVSVHYPAG---------IKSVSQN 269
+ GS L + ++ D+G Y C A + G A+ +V+V G I +
Sbjct: 2971 THGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPS 3030
Query: 270 VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENL 329
+DA C I + ++W+ + +++ +V P S + I + N
Sbjct: 3031 STVQQGQDASFKCL-IHDGAAPISLEWKTRNQELED-NVHISPNG--SIITIVGTRPSNH 3086
Query: 330 GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
G ++CV +N G A + V L V P + P VG+ L C P S
Sbjct: 3087 GTYRCVASNAYGVA-QSVVNLSVHGPPTVSVLPEGPVWVK-VGKAVTLECVSAGEPRSSA 3144
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
W++ P + + + +VL I++ SD G+Y C A+N LG +
Sbjct: 3145 RWTRIS-STPAKLEQRTYGLMDSH------AVLQISSAKPSDAGTYVCLAQNALGTAQKQ 3197
Query: 450 VKLDV 454
V++ V
Sbjct: 3198 VEVIV 3202
Score = 45.6 bits (103), Expect = 7e-04
Identities = 90/400 (22%), Positives = 147/400 (36%), Gaps = 54/400 (13%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
V AE + LT + A RC AT S T+ + +P + R E D L P +
Sbjct: 3214 VQAEEAELTVEAGHTATLRCSATGSPAP-----TIHWSKLRSPLPWQHRLEGDTLIIPRV 3268
Query: 135 ----EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADG 190
IC++ S PA + + V++ P + +V E + + A G
Sbjct: 3269 AQQDSGQYICNATS---PAGHAEATIILHVESPPYATTVPEHASVQA-GETVQLQCLAHG 3324
Query: 191 NPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV 250
PP +T+ W++ G SS R + +L+ + D+G Y C N G+A
Sbjct: 3325 TPP-LTFQWSRVG--------SSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAE 3375
Query: 251 ANISVSVHYPAG-IKSVSQNVVANPNEDAV--LSCTAIGNPL---------LAEHIKWER 298
A + V P G + + S + P L +IG + ++W +
Sbjct: 3376 AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFK 3435
Query: 299 KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
+G ++ P + L I+ G + C + G A + L+++ P +
Sbjct: 3436 EGGQLPPGHSVQD-----GVLRIQNLDQSCQGTYICQAHGPWGKA-QASAQLVIQALPSV 3489
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
+ VG C P P TWSK G L + +
Sbjct: 3490 LINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL-------------RPGIVQS 3536
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V+ I +V +D G Y C A N G + + V L V + P
Sbjct: 3537 GGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALP 3576
Score = 44.0 bits (99), Expect = 0.002
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 9/145 (6%)
Query: 13 MINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT 72
++++ + P AP + T+ AG L C +T G+P T+ W K+ S
Sbjct: 3201 IVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSAT-GSPAPTIHW----SKLRSPLPWQ 3255
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+ + I + QY C AT+ A T+ L+V P A V V +
Sbjct: 3256 HRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE--ATIILHVESPPYATTVPEHASV-QA 3312
Query: 133 GIEATLICDSASSNPPATLSWWRDG 157
G L C A PP T W R G
Sbjct: 3313 GETVQLQC-LAHGTPPLTFQWSRVG 3336
Score = 40.7 bits (91), Expect = 0.021
Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
I+ G ++ + + DAG Y C A N+ G +++ + V I S+ Q V
Sbjct: 3533 IVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQI-SMPQEVRVPAGSA 3591
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
AV C A G P I W + + P S + + L++ + ++ G + C
Sbjct: 3592 AVFPCIASGYP--TPDISWSKLDGSLPPDS-----RLENNMLMLPSVRPQDAGTYVCTAT 3644
Query: 338 NGIG 341
N G
Sbjct: 3645 NRQG 3648
Score = 37.9 bits (84), Expect = 0.15
Identities = 57/248 (22%), Positives = 89/248 (35%), Gaps = 45/248 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANI--------SVSVHYPA-------GIK 264
+ GS L + ++ D+G Y C + S G A++ S +VH PA I+
Sbjct: 2773 TRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIE 2832
Query: 265 SVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKA 324
S V D L C G + W ++G + + P L + +
Sbjct: 2833 PSSSRVAEGQTLD--LKCVVPGQ--AHAQVTWHKRGGNLPARHQVHGP-----LLRLNQV 2883
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK------SASNV--GQVGR 376
+ G + C V G+ ++ I P +P + S+S+V GQ
Sbjct: 2884 SPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLD 2943
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C TW K G LP H T+ S L ++ V+ +D G Y
Sbjct: 2944 LNCVVPGQAHAQVTWYKRGGSLPAR-------------HQTHGSQLRLHLVSPADSGEYV 2990
Query: 437 CGARNELG 444
C A + G
Sbjct: 2991 CRAASGPG 2998
Score = 37.1 bits (82), Expect = 0.26
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 356 PEMDTSPNFVK---SASNVGQVGR--LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
PE + +P V+ + S V Q G L C+ P F WS+ + PV + T+ +
Sbjct: 1670 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGR-PVPSGTQ---QR 1725
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTV 466
H+ + + SV SD G Y C RN +T+ +L VT AP + +++TV
Sbjct: 1726 HQGSELHFPSV------QPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTV 1775
Score = 35.5 bits (78), Expect = 0.79
Identities = 76/327 (23%), Positives = 119/327 (36%), Gaps = 56/327 (17%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+P + PI +++S V E + L ++ P +I TW K G S R
Sbjct: 2625 VPSVSPPIRIESSSPTVV--EGQTLDLNCVVARQPQAII-TWYKRG--------GSLPSR 2673
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKS 265
+ GS L + +++ D+G Y C A N+ A A+I +SV AG I+S
Sbjct: 2674 HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIES 2733
Query: 266 VSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAK 325
S +V D L+C G + W ++G S+ + S L +
Sbjct: 2734 SSSHVAEGETLD--LNCVVPGQ--AHAQVTWHKRG-----GSLPSHHQTRGSRLRLHHVS 2784
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLI------VKFKPEMDTSP--NFVKSASNV--GQVG 375
+ G + C V G ++ I P +P S+S V GQ
Sbjct: 2785 PADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTL 2844
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
L C TW K G LP H + +L +N V+ +D G Y
Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNLPAR-------------HQVHGPLLRLNQVSPADSGEY 2891
Query: 436 ECGARNELGFSTTTVKLDV-TSAPDQV 461
C G +V + + S+P +
Sbjct: 2892 SCQVTGSSGTLEASVLVTIEPSSPGPI 2918
Score = 35.1 bits (77), Expect = 1.0
Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 8/89 (8%)
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P++ T P AS GQ C VP P W N +P + +E +
Sbjct: 406 PQVVTPPRESIQASR-GQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG-- 462
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELG 444
L+I +V SD G+Y C A N G
Sbjct: 463 -----TLIIRDVKESDQGAYTCEAMNARG 486
Score = 33.5 bits (73), Expect = 3.2
Identities = 58/253 (22%), Positives = 95/253 (37%), Gaps = 48/253 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKSVS 267
+ GS+L + + + D+G Y C + S A++ V++ PAG I+S S
Sbjct: 2387 THGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVPALGVTPTVRIESSS 2445
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V D L+C G + W ++G + + S L + +
Sbjct: 2446 SQVAEGQTLD--LNCLVAGQ--AHAQVTWHKRGGSLPARHQVH-----GSRLRLLQVTPA 2496
Query: 328 NLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS-------PNFVKSASNV---GQVGRL 377
+ G + C V +GS+ Q+ ++V + + S P ++S+S G L
Sbjct: 2497 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2553
Query: 378 MCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
C S + TW K G LP + H S L I V +D G Y C
Sbjct: 2554 NCLVASQAPHTITWYKRGGSLP-------------SRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 438 GARNELGFSTTTV 450
N G T++
Sbjct: 2601 HVSNGAGSRETSL 2613
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 75.4 bits (177), Expect = 8e-13
Identities = 66/258 (25%), Positives = 101/258 (39%), Gaps = 22/258 (8%)
Query: 207 TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSV 266
T++ N I GS++ + + G Y C A N+ G A + +++SVH P + +
Sbjct: 3037 TRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVL 3096
Query: 267 SQNVV-ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKA 324
+ V + L C + G P +W R + T+ + + L I A
Sbjct: 3097 PEGPVWVKVGKAVTLECVSAGEP--RSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSA 3154
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCK 380
K + G + C+ N +G+A KQ V +IV +P + + G L C
Sbjct: 3155 KPSDAGTYVCLAQNALGTAQKQ-VEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCS 3213
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
PAP+ WSK LP H L+I VA D G Y C A
Sbjct: 3214 ATGSPAPTIHWSKLRSPLPW-------------QHRLEGDTLIIPRVAQQDSGQYICNAT 3260
Query: 441 NELGFSTTTVKLDVTSAP 458
+ G + T+ L V S P
Sbjct: 3261 SPAGHAEATIILHVESPP 3278
Score = 65.3 bits (152), Expect = 9e-10
Identities = 61/246 (24%), Positives = 105/246 (42%), Gaps = 13/246 (5%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVL 280
EG L + ++ + D+G Y C A + G A A I + V P +V ++ E L
Sbjct: 3238 EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL 3297
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
C A G P L +W R G + ++ +N L +A E+ G ++C V N +
Sbjct: 3298 QCLAHGTPPLT--FQWSRVGSSLPGRATA---RN--ELLHFERAAPEDSGRYRCRVTNKV 3350
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV 400
GSA + L+V+ P + + ++ QV + + KS+ A V
Sbjct: 3351 GSA-EAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQL-ETKSIGAS--VEFHCAVPSDR 3406
Query: 401 NTSTKYFAEFHK--NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T ++F E + H VL I N+ S G+Y C A G + + +L + + P
Sbjct: 3407 GTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALP 3466
Query: 459 DQVVSL 464
++++
Sbjct: 3467 SVLINI 3472
Score = 57.2 bits (132), Expect = 2e-07
Identities = 59/250 (23%), Positives = 101/250 (40%), Gaps = 26/250 (10%)
Query: 217 RIISEGSMLNMTKLTRHDAGIYTCEAVN----SQGAAVANISVSVHYPAGIKSVSQ-NVV 271
R + +L + + DAG Y C N QG A ++ S A + S+ +
Sbjct: 1796 RAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1855
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLG 330
P + A C+A G+P ++W G ++ K+ L + + +
Sbjct: 1856 VQPGQLAEFRCSATGSP--TPTLEWTGGPGGQLPAKAQIHG-----GILRLPAVEPTDQA 1908
Query: 331 NFQCVVNNGIGSATKQDVMLIVKFK-PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
+ C ++ G + V+ + P + SP ++ + G+ RL C+ VP+ +
Sbjct: 1909 QYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPE--RTQVHAGRTVRLYCRAAGVPSATI 1966
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
TW K G LP A + D T LLI + T+D G Y C A + G +
Sbjct: 1967 TWRKEGGSLPPQ------ARSERTDIAT----LLIPAITTADAGFYLCVATSPAGTAQAR 2016
Query: 450 VKLDVTSAPD 459
+++ V SA D
Sbjct: 2017 IQVVVLSASD 2026
Score = 56.4 bits (130), Expect = 4e-07
Identities = 99/480 (20%), Positives = 177/480 (36%), Gaps = 68/480 (14%)
Query: 23 APMITGYVPGTTLAA-GTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTTDKAVSAEIS 81
AP++ P ++ G L C G+P W + D + + T + +E+
Sbjct: 1654 APLVVEVHPARSIVPQGGSHSLRC-QVSGSPPHYFYWSREDGR-PVPSGTQQRHQGSELH 1711
Query: 82 ILTNVTDNQAQYRCEATN-SATEIPLFETVTLNVHFAPEAVKVRAE-PDVLKPGIEATLI 139
+ + Y C N + E + P V V + ++PG + T I
Sbjct: 1712 FPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFI 1771
Query: 140 CDSASSNPPATLSWWR-------------DGI-PVQNAPIFDD----TTSYNTVGIENEP 181
C + S +P TL W R +GI ++N + D T N ++
Sbjct: 1772 CTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGT 1831
Query: 182 LIISVRADG---------NPPSIT--------YTWTKDGLPITQSSYSSGNDRIIS---- 220
+ V+A G +PP +T + + G P ++ G +
Sbjct: 1832 ATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQ 1891
Query: 221 -EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG--IKSVSQNVVANPNED 277
G +L + + D Y C A +S G VA + VH G ++ + +
Sbjct: 1892 IHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRT 1951
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
L C A G P + I W ++G + P++ + E ++ + L+I + + G + CV
Sbjct: 1952 VRLYCRAAGVP--SATITWRKEGGSLPPQARS-ERTDIAT-LLIPAITTADAGFYLCVAT 2007
Query: 338 NGIGSATKQDVMLIVKFKPEMDTSPNFVKSAS---NVGQVGRLMCKCKSVPAPSFTWSKN 394
+ G+A + + ++V + P ++S+S GQ L C TW +
Sbjct: 2008 SPAGTAQAR-IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRR 2066
Query: 395 GVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDV 454
G LP +T + S L + V+ +D G Y C N G ++ + V
Sbjct: 2067 GGSLPPHTQ-------------VHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSV 2113
Score = 53.6 bits (123), Expect = 3e-06
Identities = 80/323 (24%), Positives = 119/323 (36%), Gaps = 49/323 (15%)
Query: 193 PSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVAN 252
PS T TW K+G + + S D + L + +T DAG Y C A + G A A
Sbjct: 1962 PSATITWRKEGGSLPPQARSERTDI-----ATLLIPAITTADAGFYLCVATSPAGTAQAR 2016
Query: 253 ISVSV-----HYPAGIKSVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKS 307
I V V P +K S + + L+C G+ + W R+G + P +
Sbjct: 2017 IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGS--AHAQVTWYRRGGSLPPHT 2074
Query: 308 VTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIG---SATKQDVMLIVKFKPEMDTSPNF 364
S L + + + G + C V NG G ++ V+ P P
Sbjct: 2075 QVH-----GSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGS 2129
Query: 365 VK------SASNV--GQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHI 416
+ S+S+V GQ L C TW K G LP H
Sbjct: 2130 TRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPAR-------------HQ 2176
Query: 417 TYTSVLLINNVATSDYGSYEC---GARNELGFST-TTVKLDVTSA---PDQVVSLTVTNV 469
T+ S+L ++ V +D G Y C G L S T++ V P ++ S + T
Sbjct: 2177 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2236
Query: 470 THSTVTLEWVPGFDGGLQ-SWYR 491
T+ L V Q +WY+
Sbjct: 2237 EGQTLDLSCVVAGQAHAQVTWYK 2259
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/253 (24%), Positives = 100/253 (39%), Gaps = 42/253 (16%)
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH------------YPAGIKSVSQN 269
GS L + ++T D+G Y C V S G A++ V++ YP I+S S +
Sbjct: 2464 GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSAS 2523
Query: 270 VVANPNEDAVLSCTAIGNPLLAEH-IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
+ D L+C A H I W ++G S+ + + S L I + +
Sbjct: 2524 LANGHTLD--LNCLVASQ---APHTITWYKRG-----GSLPSRHQIVGSRLRIPQVTPAD 2573
Query: 329 LGNFQCVVNNGIGSATKQDVMLI----VKFKPEMDTSPNFVKSASNV--GQVGRLMCKCK 382
G + C V+NG GS ++ I P + S+ V GQ L C
Sbjct: 2574 SGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 2633
Query: 383 SVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNE 442
P TW K G LP + H T+ S L ++ ++ +D G Y C A N
Sbjct: 2634 RQPQAIITWYKRGGSLP-------------SRHQTHGSHLRLHQMSVADSGEYVCRANNN 2680
Query: 443 LGFSTTTVKLDVT 455
+ ++ + V+
Sbjct: 2681 IDALEASIVISVS 2693
Score = 52.4 bits (120), Expect = 6e-06
Identities = 59/246 (23%), Positives = 104/246 (42%), Gaps = 33/246 (13%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNEDAV 279
+ +L + L + G Y C+A G A A+ + + P+ + ++ +V AV
Sbjct: 3426 QDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAV 3485
Query: 280 -LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE--NLGNFQCVV 336
C A+G+P + W + G + P V S ++R A E + G ++C
Sbjct: 3486 EFECLALGDP--KPQVTWSKVGGHLRPGIVQ-------SGGVVRIAHVELADAGQYRCTA 3536
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ T+ V+L+V+ P++ + P V+ + G C P P +WSK
Sbjct: 3537 TNAAGT-TQSHVLLLVQALPQI-SMPQEVRVPA--GSAAVFPCIASGYPTPDISWSKLDG 3592
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
LP ++ + ++L++ +V D G+Y C A N G L V
Sbjct: 3593 SLPPDSRLE-------------NNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV-- 3637
Query: 457 APDQVV 462
P++VV
Sbjct: 3638 -PERVV 3642
Score = 47.2 bits (107), Expect = 2e-04
Identities = 59/232 (25%), Positives = 91/232 (39%), Gaps = 36/232 (15%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--------PAGIKSVSQNVV 271
+ GS+L + ++T D+G Y C V + G A++ V++ P I+S S V
Sbjct: 2177 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2236
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGN 331
D LSC G + W ++G S+ + S L I +A + G
Sbjct: 2237 EGQTLD--LSCVVAGQ--AHAQVTWYKRG-----GSLPARHQVRGSRLYIFQASPADAGQ 2287
Query: 332 FQCVVNNGIGSA---TKQDVMLIVKFKPEMDTSPNFVK-SASNV--GQVGRLMCKCKSVP 385
+ C +NG+ ++ T P T P ++ S+S V GQ L C
Sbjct: 2288 YVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQS 2347
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
TW K G LPV H T+ S+L + + +D G Y C
Sbjct: 2348 HAQVTWHKRGGSLPVR-------------HQTHGSLLRLYQASPADSGEYVC 2386
Score = 46.4 bits (105), Expect = 4e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 23/245 (9%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV-ANISVSVHYPAG---------IKSVSQN 269
+ GS L + ++ D+G Y C A + G A+ +V+V G I +
Sbjct: 2950 THGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPS 3009
Query: 270 VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENL 329
+DA C I + ++W+ + +++ +V P S + I + N
Sbjct: 3010 STVQQGQDASFKCL-IHDGAAPISLEWKTRNQELED-NVHISPNG--SIITIVGTRPSNH 3065
Query: 330 GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
G ++CV +N G A + V L V P + P VG+ L C P S
Sbjct: 3066 GTYRCVASNAYGVA-QSVVNLSVHGPPTVSVLPEGPVWVK-VGKAVTLECVSAGEPRSSA 3123
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
W++ P + + + +VL I++ SD G+Y C A+N LG +
Sbjct: 3124 RWTRIS-STPAKLEQRTYGLMDSH------AVLQISSAKPSDAGTYVCLAQNALGTAQKQ 3176
Query: 450 VKLDV 454
V++ V
Sbjct: 3177 VEVIV 3181
Score = 45.6 bits (103), Expect = 7e-04
Identities = 90/400 (22%), Positives = 147/400 (36%), Gaps = 54/400 (13%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
V AE + LT + A RC AT S T+ + +P + R E D L P +
Sbjct: 3193 VQAEEAELTVEAGHTATLRCSATGSPAP-----TIHWSKLRSPLPWQHRLEGDTLIIPRV 3247
Query: 135 ----EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADG 190
IC++ S PA + + V++ P + +V E + + A G
Sbjct: 3248 AQQDSGQYICNATS---PAGHAEATIILHVESPPYATTVPEHASVQA-GETVQLQCLAHG 3303
Query: 191 NPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV 250
PP +T+ W++ G SS R + +L+ + D+G Y C N G+A
Sbjct: 3304 TPP-LTFQWSRVG--------SSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAE 3354
Query: 251 ANISVSVHYPAG-IKSVSQNVVANPNEDAV--LSCTAIGNPL---------LAEHIKWER 298
A + V P G + + S + P L +IG + ++W +
Sbjct: 3355 AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFK 3414
Query: 299 KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
+G ++ P + L I+ G + C + G A + L+++ P +
Sbjct: 3415 EGGQLPPGHSVQD-----GVLRIQNLDQSCQGTYICQAHGPWGKA-QASAQLVIQALPSV 3468
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
+ VG C P P TWSK G L + +
Sbjct: 3469 LINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL-------------RPGIVQS 3515
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V+ I +V +D G Y C A N G + + V L V + P
Sbjct: 3516 GGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALP 3555
Score = 44.0 bits (99), Expect = 0.002
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 9/145 (6%)
Query: 13 MINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT 72
++++ + P AP + T+ AG L C +T G+P T+ W K+ S
Sbjct: 3180 IVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSAT-GSPAPTIHW----SKLRSPLPWQ 3234
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+ + I + QY C AT+ A T+ L+V P A V V +
Sbjct: 3235 HRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE--ATIILHVESPPYATTVPEHASV-QA 3291
Query: 133 GIEATLICDSASSNPPATLSWWRDG 157
G L C A PP T W R G
Sbjct: 3292 GETVQLQC-LAHGTPPLTFQWSRVG 3315
Score = 40.7 bits (91), Expect = 0.021
Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
I+ G ++ + + DAG Y C A N+ G +++ + V I S+ Q V
Sbjct: 3512 IVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQI-SMPQEVRVPAGSA 3570
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
AV C A G P I W + + P S + + L++ + ++ G + C
Sbjct: 3571 AVFPCIASGYP--TPDISWSKLDGSLPPDS-----RLENNMLMLPSVRPQDAGTYVCTAT 3623
Query: 338 NGIG 341
N G
Sbjct: 3624 NRQG 3627
Score = 37.9 bits (84), Expect = 0.15
Identities = 57/248 (22%), Positives = 89/248 (35%), Gaps = 45/248 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANI--------SVSVHYPA-------GIK 264
+ GS L + ++ D+G Y C + S G A++ S +VH PA I+
Sbjct: 2752 TRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIE 2811
Query: 265 SVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKA 324
S V D L C G + W ++G + + P L + +
Sbjct: 2812 PSSSRVAEGQTLD--LKCVVPGQ--AHAQVTWHKRGGNLPARHQVHGP-----LLRLNQV 2862
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK------SASNV--GQVGR 376
+ G + C V G+ ++ I P +P + S+S+V GQ
Sbjct: 2863 SPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLD 2922
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C TW K G LP H T+ S L ++ V+ +D G Y
Sbjct: 2923 LNCVVPGQAHAQVTWYKRGGSLPAR-------------HQTHGSQLRLHLVSPADSGEYV 2969
Query: 437 CGARNELG 444
C A + G
Sbjct: 2970 CRAASGPG 2977
Score = 37.1 bits (82), Expect = 0.26
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 356 PEMDTSPNFVK---SASNVGQVGR--LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEF 410
PE + +P V+ + S V Q G L C+ P F WS+ + PV + T+ +
Sbjct: 1649 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGR-PVPSGTQ---QR 1704
Query: 411 HKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAPDQVVSLTV 466
H+ + + SV SD G Y C RN +T+ +L VT AP + +++TV
Sbjct: 1705 HQGSELHFPSV------QPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTV 1754
Score = 35.5 bits (78), Expect = 0.79
Identities = 76/327 (23%), Positives = 119/327 (36%), Gaps = 56/327 (17%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+P + PI +++S V E + L ++ P +I TW K G S R
Sbjct: 2604 VPSVSPPIRIESSSPTVV--EGQTLDLNCVVARQPQAII-TWYKRG--------GSLPSR 2652
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKS 265
+ GS L + +++ D+G Y C A N+ A A+I +SV AG I+S
Sbjct: 2653 HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIES 2712
Query: 266 VSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAK 325
S +V D L+C G + W ++G S+ + S L +
Sbjct: 2713 SSSHVAEGETLD--LNCVVPGQ--AHAQVTWHKRG-----GSLPSHHQTRGSRLRLHHVS 2763
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLI------VKFKPEMDTSP--NFVKSASNV--GQVG 375
+ G + C V G ++ I P +P S+S V GQ
Sbjct: 2764 PADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTL 2823
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
L C TW K G LP H + +L +N V+ +D G Y
Sbjct: 2824 DLKCVVPGQAHAQVTWHKRGGNLPAR-------------HQVHGPLLRLNQVSPADSGEY 2870
Query: 436 ECGARNELGFSTTTVKLDV-TSAPDQV 461
C G +V + + S+P +
Sbjct: 2871 SCQVTGSSGTLEASVLVTIEPSSPGPI 2897
Score = 35.1 bits (77), Expect = 1.0
Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 8/89 (8%)
Query: 356 PEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDH 415
P++ T P AS GQ C VP P W N +P + +E +
Sbjct: 385 PQVVTPPRESIQASR-GQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG-- 441
Query: 416 ITYTSVLLINNVATSDYGSYECGARNELG 444
L+I +V SD G+Y C A N G
Sbjct: 442 -----TLIIRDVKESDQGAYTCEAMNARG 465
Score = 33.5 bits (73), Expect = 3.2
Identities = 58/253 (22%), Positives = 95/253 (37%), Gaps = 48/253 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKSVS 267
+ GS+L + + + D+G Y C + S A++ V++ PAG I+S S
Sbjct: 2366 THGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVPALGVTPTVRIESSS 2424
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V D L+C G + W ++G + + S L + +
Sbjct: 2425 SQVAEGQTLD--LNCLVAGQ--AHAQVTWHKRGGSLPARHQVH-----GSRLRLLQVTPA 2475
Query: 328 NLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS-------PNFVKSASNV---GQVGRL 377
+ G + C V +GS+ Q+ ++V + + S P ++S+S G L
Sbjct: 2476 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2532
Query: 378 MCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
C S + TW K G LP + H S L I V +D G Y C
Sbjct: 2533 NCLVASQAPHTITWYKRGGSLP-------------SRHQIVGSRLRIPQVTPADSGEYVC 2579
Query: 438 GARNELGFSTTTV 450
N G T++
Sbjct: 2580 HVSNGAGSRETSL 2592
>BC101801-1|AAI01802.1| 778|Homo sapiens kin of IRRE like 3
protein.
Length = 778
Score = 74.9 bits (176), Expect = 1e-12
Identities = 74/298 (24%), Positives = 131/298 (43%), Gaps = 30/298 (10%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I +Q+ P+ + + V +E+ + A NP Y W K G I ++S
Sbjct: 244 IDIQHPPLVNLSVEPQPV-LEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEAS------- 295
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
G + T + + +CE N+ G+ + +V V++ + + Q+++ + D
Sbjct: 296 ----GEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSD 351
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC-VV 336
A+ SC GNP L I W ++G + V K LT ++ + E+ G + C V
Sbjct: 352 AIFSCAWTGNPSLT--IVWMKRGSGV----VLSNEKTLT----LKSVRQEDAGKYVCRAV 401
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS-FTWSKNG 395
+G A +++V L V P + ++ + A + G+ G++ C +S P P WS
Sbjct: 402 VPRVG-AGEREVTLTVNGPPIISSTQ--TQHALH-GEKGQIKCFIRSTPPPDRIAWSWKE 457
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS-YECGARNELGFSTTTVKL 452
L TS +Y E + S L I+N+ +D+ + Y C A N G T ++L
Sbjct: 458 NVLESGTSGRYTVETISTEE-GVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRL 514
Score = 54.0 bits (124), Expect = 2e-06
Identities = 76/316 (24%), Positives = 122/316 (38%), Gaps = 41/316 (12%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT--KT-----T 72
PP P+I G P +L AG L C + P A++ W + + I+ T KT
Sbjct: 146 PPDDPVILGG-PVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGK 204
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+++ + + I +N C ATN A +VT+++ P V + EP +
Sbjct: 205 RESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQH-PPLVNLSVEPQPVLE 263
Query: 133 GIEATLICDSASSNPPAT-LSWWRDGIPVQNA--PIFDDTTSY------------NTVGI 177
T C SA +NP T W + G ++ A ++ T Y N +G
Sbjct: 264 DNVVTFHC-SAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGS 322
Query: 178 ENEPLIISV----RADGNPPSITYTWTKDGL---------PITQSSYSSGNDRIISEGSM 224
N + V R P S+ D + +T G+ ++S
Sbjct: 323 TNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKT 382
Query: 225 LNMTKLTRHDAGIYTCEAVNSQ-GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + + + DAG Y C AV + GA ++++V+ P I S +Q A E + C
Sbjct: 383 LTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISS-TQTQHALHGEKGQIKCF 441
Query: 284 AIGNPLLAEHIKWERK 299
P + I W K
Sbjct: 442 IRSTP-PPDRIAWSWK 456
Score = 45.6 bits (103), Expect = 7e-04
Identities = 50/222 (22%), Positives = 86/222 (38%), Gaps = 19/222 (8%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD---AG 236
+PL ++ AD P+ + W + G I ++YS R S+++ ++ D
Sbjct: 164 DPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQ 223
Query: 237 IYTCEAVNS--QGAAVANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
C A N G ++++ + +P + SV V N C+A NP + ++
Sbjct: 224 SIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNV-VTFHCSAKANPAVTQY 282
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+W ++G I S + Y + S C V N +GS T + V
Sbjct: 283 -RWAKRGQIIKEASGEVY-RTTVDYTYFSEPVS-------CEVTNALGS-TNLSRTVDVY 332
Query: 354 FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
F P M T P + ++G C P+ + W K G
Sbjct: 333 FGPRMTTEPQSL--LVDLGSDAIFSCAWTGNPSLTIVWMKRG 372
>BC101775-1|AAI01776.1| 778|Homo sapiens kin of IRRE like 3
(Drosophila) protein.
Length = 778
Score = 74.9 bits (176), Expect = 1e-12
Identities = 74/298 (24%), Positives = 131/298 (43%), Gaps = 30/298 (10%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I +Q+ P+ + + V +E+ + A NP Y W K G I ++S
Sbjct: 244 IDIQHPPLVNLSVEPQPV-LEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEAS------- 295
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
G + T + + +CE N+ G+ + +V V++ + + Q+++ + D
Sbjct: 296 ----GEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSD 351
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC-VV 336
A+ SC GNP L I W ++G + V K LT ++ + E+ G + C V
Sbjct: 352 AIFSCAWTGNPSLT--IVWMKRGSGV----VLSNEKTLT----LKSVRQEDAGKYVCRAV 401
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS-FTWSKNG 395
+G A +++V L V P + ++ + A + G+ G++ C +S P P WS
Sbjct: 402 VPRVG-AGEREVTLTVNGPPIISSTQ--TQHALH-GEKGQIKCFIRSTPPPDRIAWSWKE 457
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS-YECGARNELGFSTTTVKL 452
L TS +Y E + S L I+N+ +D+ + Y C A N G T ++L
Sbjct: 458 NVLESGTSGRYTVETISTEE-GVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRL 514
Score = 54.0 bits (124), Expect = 2e-06
Identities = 76/316 (24%), Positives = 122/316 (38%), Gaps = 41/316 (12%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT--KT-----T 72
PP P+I G P +L AG L C + P A++ W + + I+ T KT
Sbjct: 146 PPDDPVILGG-PVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGK 204
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+++ + + I +N C ATN A +VT+++ P V + EP +
Sbjct: 205 RESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQH-PPLVNLSVEPQPVLE 263
Query: 133 GIEATLICDSASSNPPAT-LSWWRDGIPVQNA--PIFDDTTSY------------NTVGI 177
T C SA +NP T W + G ++ A ++ T Y N +G
Sbjct: 264 DNVVTFHC-SAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGS 322
Query: 178 ENEPLIISV----RADGNPPSITYTWTKDGL---------PITQSSYSSGNDRIISEGSM 224
N + V R P S+ D + +T G+ ++S
Sbjct: 323 TNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKT 382
Query: 225 LNMTKLTRHDAGIYTCEAVNSQ-GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + + + DAG Y C AV + GA ++++V+ P I S +Q A E + C
Sbjct: 383 LTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISS-TQTQHALHGEKGQIKCF 441
Query: 284 AIGNPLLAEHIKWERK 299
P + I W K
Sbjct: 442 IRSTP-PPDRIAWSWK 456
Score = 45.6 bits (103), Expect = 7e-04
Identities = 50/222 (22%), Positives = 86/222 (38%), Gaps = 19/222 (8%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD---AG 236
+PL ++ AD P+ + W + G I ++YS R S+++ ++ D
Sbjct: 164 DPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQ 223
Query: 237 IYTCEAVNS--QGAAVANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
C A N G ++++ + +P + SV V N C+A NP + ++
Sbjct: 224 SIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNV-VTFHCSAKANPAVTQY 282
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+W ++G I S + Y + S C V N +GS T + V
Sbjct: 283 -RWAKRGQIIKEASGEVY-RTTVDYTYFSEPVS-------CEVTNALGS-TNLSRTVDVY 332
Query: 354 FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
F P M T P + ++G C P+ + W K G
Sbjct: 333 FGPRMTTEPQSL--LVDLGSDAIFSCAWTGNPSLTIVWMKRG 372
>AY358743-1|AAQ89103.1| 600|Homo sapiens NEPH2 protein.
Length = 600
Score = 74.9 bits (176), Expect = 1e-12
Identities = 74/298 (24%), Positives = 131/298 (43%), Gaps = 30/298 (10%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I +Q+ P+ + + V +E+ + A NP Y W K G I ++S
Sbjct: 244 IDIQHPPLVNLSVEPQPV-LEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEAS------- 295
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
G + T + + +CE N+ G+ + +V V++ + + Q+++ + D
Sbjct: 296 ----GEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSD 351
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC-VV 336
A+ SC GNP L I W ++G + V K LT ++ + E+ G + C V
Sbjct: 352 AIFSCAWTGNPSLT--IVWMKRGSGV----VLSNEKTLT----LKSVRQEDAGKYVCRAV 401
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS-FTWSKNG 395
+G A +++V L V P + ++ + A + G+ G++ C +S P P WS
Sbjct: 402 VPRVG-AGEREVTLTVNGPPIISSTQ--TQHALH-GEKGQIKCFIRSTPPPDRIAWSWKE 457
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS-YECGARNELGFSTTTVKL 452
L TS +Y E + S L I+N+ +D+ + Y C A N G T ++L
Sbjct: 458 NVLESGTSGRYTVETISTEE-GVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRL 514
Score = 54.0 bits (124), Expect = 2e-06
Identities = 76/316 (24%), Positives = 122/316 (38%), Gaps = 41/316 (12%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT--KT-----T 72
PP P+I G P +L AG L C + P A++ W + + I+ T KT
Sbjct: 146 PPDDPVILGG-PVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGK 204
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+++ + + I +N C ATN A +VT+++ P V + EP +
Sbjct: 205 RESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQH-PPLVNLSVEPQPVLE 263
Query: 133 GIEATLICDSASSNPPAT-LSWWRDGIPVQNA--PIFDDTTSY------------NTVGI 177
T C SA +NP T W + G ++ A ++ T Y N +G
Sbjct: 264 DNVVTFHC-SAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGS 322
Query: 178 ENEPLIISV----RADGNPPSITYTWTKDGL---------PITQSSYSSGNDRIISEGSM 224
N + V R P S+ D + +T G+ ++S
Sbjct: 323 TNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKT 382
Query: 225 LNMTKLTRHDAGIYTCEAVNSQ-GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + + + DAG Y C AV + GA ++++V+ P I S +Q A E + C
Sbjct: 383 LTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISS-TQTQHALHGEKGQIKCF 441
Query: 284 AIGNPLLAEHIKWERK 299
P + I W K
Sbjct: 442 IRSTP-PPDRIAWSWK 456
Score = 45.6 bits (103), Expect = 7e-04
Identities = 50/222 (22%), Positives = 86/222 (38%), Gaps = 19/222 (8%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD---AG 236
+PL ++ AD P+ + W + G I ++YS R S+++ ++ D
Sbjct: 164 DPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQ 223
Query: 237 IYTCEAVNS--QGAAVANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
C A N G ++++ + +P + SV V N C+A NP + ++
Sbjct: 224 SIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNV-VTFHCSAKANPAVTQY 282
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+W ++G I S + Y + S C V N +GS T + V
Sbjct: 283 -RWAKRGQIIKEASGEVY-RTTVDYTYFSEPVS-------CEVTNALGS-TNLSRTVDVY 332
Query: 354 FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
F P M T P + ++G C P+ + W K G
Sbjct: 333 FGPRMTTEPQSL--LVDLGSDAIFSCAWTGNPSLTIVWMKRG 372
>AF480410-1|AAN73042.1| 778|Homo sapiens NPEH2 protein.
Length = 778
Score = 74.9 bits (176), Expect = 1e-12
Identities = 74/298 (24%), Positives = 131/298 (43%), Gaps = 30/298 (10%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I +Q+ P+ + + V +E+ + A NP Y W K G I ++S
Sbjct: 244 IDIQHPPLVNLSVEPQPV-LEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEAS------- 295
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
G + T + + +CE N+ G+ + +V V++ + + Q+++ + D
Sbjct: 296 ----GEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSD 351
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC-VV 336
A+ SC GNP L I W ++G + V K LT ++ + E+ G + C V
Sbjct: 352 AIFSCAWTGNPSLT--IVWMKRGSGV----VLSNEKTLT----LKSVRQEDAGKYVCRAV 401
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS-FTWSKNG 395
+G A +++V L V P + ++ + A + G+ G++ C +S P P WS
Sbjct: 402 VPRVG-AGEREVTLTVNGPPIISSTQ--TQHALH-GEKGQIKCFIRSTPPPDRIAWSWKE 457
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS-YECGARNELGFSTTTVKL 452
L TS +Y E + S L I+N+ +D+ + Y C A N G T ++L
Sbjct: 458 NVLESGTSGRYTVETISTEE-GVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRL 514
Score = 54.0 bits (124), Expect = 2e-06
Identities = 76/316 (24%), Positives = 122/316 (38%), Gaps = 41/316 (12%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT--KT-----T 72
PP P+I G P +L AG L C + P A++ W + + I+ T KT
Sbjct: 146 PPDDPVILGG-PVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGK 204
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+++ + + I +N C ATN A +VT+++ P V + EP +
Sbjct: 205 RESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQH-PPLVNLSVEPQPVLE 263
Query: 133 GIEATLICDSASSNPPAT-LSWWRDGIPVQNA--PIFDDTTSY------------NTVGI 177
T C SA +NP T W + G ++ A ++ T Y N +G
Sbjct: 264 DNVVTFHC-SAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGS 322
Query: 178 ENEPLIISV----RADGNPPSITYTWTKDGL---------PITQSSYSSGNDRIISEGSM 224
N + V R P S+ D + +T G+ ++S
Sbjct: 323 TNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKT 382
Query: 225 LNMTKLTRHDAGIYTCEAVNSQ-GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + + + DAG Y C AV + GA ++++V+ P I S +Q A E + C
Sbjct: 383 LTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISS-TQTQHALHGEKGQIKCF 441
Query: 284 AIGNPLLAEHIKWERK 299
P + I W K
Sbjct: 442 IRSTP-PPDRIAWSWK 456
Score = 45.6 bits (103), Expect = 7e-04
Identities = 50/222 (22%), Positives = 86/222 (38%), Gaps = 19/222 (8%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD---AG 236
+PL ++ AD P+ + W + G I ++YS R S+++ ++ D
Sbjct: 164 DPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQ 223
Query: 237 IYTCEAVNS--QGAAVANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
C A N G ++++ + +P + SV V N C+A NP + ++
Sbjct: 224 SIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNV-VTFHCSAKANPAVTQY 282
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+W ++G I S + Y + S C V N +GS T + V
Sbjct: 283 -RWAKRGQIIKEASGEVY-RTTVDYTYFSEPVS-------CEVTNALGS-TNLSRTVDVY 332
Query: 354 FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
F P M T P + ++G C P+ + W K G
Sbjct: 333 FGPRMTTEPQSL--LVDLGSDAIFSCAWTGNPSLTIVWMKRG 372
>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
heparan sulfate proteoglycan core protein precursor
protein.
Length = 2331
Score = 74.9 bits (176), Expect = 1e-12
Identities = 67/258 (25%), Positives = 103/258 (39%), Gaps = 22/258 (8%)
Query: 207 TQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSV 266
T++ N I GS++ + + G Y C A N+ G A + +++SVH P + +
Sbjct: 998 TRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVL 1057
Query: 267 SQNVV-ANPNEDAVLSCTAIGNPLLAEHIKWER-KGYKIDPKSVTFEPKNLTSYLIIRKA 324
+ V + L C + G P +W R + T+ + + L I A
Sbjct: 1058 PEGPVWVKVGKAVTLECVSAGEP--RSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSA 1115
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNV----GQVGRLMCK 380
K + G + C+ N +G+A KQ V +IV +P + + G L C
Sbjct: 1116 KPSDAGTYVCLAQNALGTAQKQ-VEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCS 1174
Query: 381 CKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGAR 440
PAP+ WSK LP +Y E L+I VA D G Y C A
Sbjct: 1175 ATGSPAPTIHWSKLRSPLP----WQYRLE---------GDTLIIPRVAQQDSGQYICNAT 1221
Query: 441 NELGFSTTTVKLDVTSAP 458
+ G + T+ L V S P
Sbjct: 1222 SPAGHAEATIILHVESPP 1239
Score = 65.3 bits (152), Expect = 9e-10
Identities = 61/246 (24%), Positives = 105/246 (42%), Gaps = 13/246 (5%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNEDAVL 280
EG L + ++ + D+G Y C A + G A A I + V P +V ++ E L
Sbjct: 1199 EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL 1258
Query: 281 SCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGI 340
C A G P L +W R G + ++ +N L +A E+ G ++C V N +
Sbjct: 1259 QCLAHGTPPLT--FQWSRVGSSLPGRATA---RN--ELLHFERAAPEDSGRYRCRVTNKV 1311
Query: 341 GSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPV 400
GSA + L+V+ P + + ++ QV + + KS+ A V
Sbjct: 1312 GSA-EAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQL-ETKSIGAS--VEFHCAVPSDR 1367
Query: 401 NTSTKYFAEFHK--NDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
T ++F E + H VL I N+ S G+Y C A G + + +L + + P
Sbjct: 1368 GTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALP 1427
Query: 459 DQVVSL 464
++++
Sbjct: 1428 SVLINI 1433
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/253 (24%), Positives = 100/253 (39%), Gaps = 42/253 (16%)
Query: 222 GSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH------------YPAGIKSVSQN 269
GS L + ++T D+G Y C V S G A++ V++ YP I+S S +
Sbjct: 425 GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSAS 484
Query: 270 VVANPNEDAVLSCTAIGNPLLAEH-IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSEN 328
+ D L+C A H I W ++G S+ + + S L I + +
Sbjct: 485 LANGHTLD--LNCLVASQ---APHTITWYKRG-----GSLPSRHQIVGSRLRIPQVTPAD 534
Query: 329 LGNFQCVVNNGIGSATKQDVMLI----VKFKPEMDTSPNFVKSASNV--GQVGRLMCKCK 382
G + C V+NG GS ++ I P + S+ V GQ L C
Sbjct: 535 SGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 594
Query: 383 SVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNE 442
P TW K G LP + H T+ S L ++ ++ +D G Y C A N
Sbjct: 595 RQPQAIITWYKRGGSLP-------------SRHQTHGSHLRLHQMSVADSGEYVCRANNN 641
Query: 443 LGFSTTTVKLDVT 455
+ ++ + V+
Sbjct: 642 IDALEASIVISVS 654
Score = 52.4 bits (120), Expect = 6e-06
Identities = 59/246 (23%), Positives = 104/246 (42%), Gaps = 33/246 (13%)
Query: 221 EGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVH-YPAGIKSVSQNVVANPNEDAV 279
+ +L + L + G Y C+A G A A+ + + P+ + ++ +V AV
Sbjct: 1387 QDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAV 1446
Query: 280 -LSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE--NLGNFQCVV 336
C A+G+P + W + G + P V S ++R A E + G ++C
Sbjct: 1447 EFECLALGDP--KPQVTWSKVGGHLRPGIVQ-------SGGVVRIAHVELADAGQYRCTA 1497
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGV 396
N G+ T+ V+L+V+ P++ + P V+ + G C P P +WSK
Sbjct: 1498 TNAAGT-TQSHVLLLVQALPQI-SMPQEVRVPA--GSAAVFPCIASGYPTPDISWSKLDG 1553
Query: 397 KLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTS 456
LP ++ + ++L++ +V D G+Y C A N G L V
Sbjct: 1554 SLPPDSRLE-------------NNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV-- 1598
Query: 457 APDQVV 462
P++VV
Sbjct: 1599 -PERVV 1603
Score = 47.2 bits (107), Expect = 2e-04
Identities = 59/232 (25%), Positives = 91/232 (39%), Gaps = 36/232 (15%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHY--------PAGIKSVSQNVV 271
+ GS+L + ++T D+G Y C V + G A++ V++ P I+S S V
Sbjct: 138 THGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 197
Query: 272 ANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGN 331
D LSC G + W ++G S+ + S L I +A + G
Sbjct: 198 EGQTLD--LSCVVAGQ--AHAQVTWYKRG-----GSLPARHQVRGSRLYIFQASPADAGQ 248
Query: 332 FQCVVNNGIGSA---TKQDVMLIVKFKPEMDTSPNFVK-SASNV--GQVGRLMCKCKSVP 385
+ C +NG+ ++ T P T P ++ S+S V GQ L C
Sbjct: 249 YVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQS 308
Query: 386 APSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
TW K G LPV H T+ S+L + + +D G Y C
Sbjct: 309 HAQVTWHKRGGSLPVR-------------HQTHGSLLRLYQASPADSGEYVC 347
Score = 46.4 bits (105), Expect = 4e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 23/245 (9%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV-ANISVSVHYPAG---------IKSVSQN 269
+ GS L + ++ D+G Y C A + G A+ +V+V G I +
Sbjct: 911 THGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPS 970
Query: 270 VVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENL 329
+DA C I + ++W+ + +++ +V P S + I + N
Sbjct: 971 STVQQGQDASFKCL-IHDGAAPISLEWKTRNQELED-NVHISPNG--SIITIVGTRPSNH 1026
Query: 330 GNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSF 389
G ++CV +N G A + V L V P + P VG+ L C P S
Sbjct: 1027 GTYRCVASNAYGVA-QSVVNLSVHGPPTVSVLPEGPVWVK-VGKAVTLECVSAGEPRSSA 1084
Query: 390 TWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYECGARNELGFSTTT 449
W++ P + + + +VL I++ SD G+Y C A+N LG +
Sbjct: 1085 RWTRIS-STPAKLEQRTYGLMDSH------AVLQISSAKPSDAGTYVCLAQNALGTAQKQ 1137
Query: 450 VKLDV 454
V++ V
Sbjct: 1138 VEVIV 1142
Score = 46.4 bits (105), Expect = 4e-04
Identities = 90/400 (22%), Positives = 147/400 (36%), Gaps = 54/400 (13%)
Query: 76 VSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLK-PGI 134
V AE + LT + A RC AT S T+ + +P + R E D L P +
Sbjct: 1154 VQAEEAELTVEAGHTATLRCSATGSPAP-----TIHWSKLRSPLPWQYRLEGDTLIIPRV 1208
Query: 135 ----EATLICDSASSNPPATLSWWRDGIPVQNAPIFDDTTSYNTVGIENEPLIISVRADG 190
IC++ S PA + + V++ P + +V E + + A G
Sbjct: 1209 AQQDSGQYICNATS---PAGHAEATIILHVESPPYATTVPEHASVQA-GETVQLQCLAHG 1264
Query: 191 NPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAV 250
PP +T+ W++ G SS R + +L+ + D+G Y C N G+A
Sbjct: 1265 TPP-LTFQWSRVG--------SSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAE 1315
Query: 251 ANISVSVHYPAG-IKSVSQNVVANPNEDAV--LSCTAIGNPL---------LAEHIKWER 298
A + V P G + + S + P L +IG + ++W +
Sbjct: 1316 AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFK 1375
Query: 299 KGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEM 358
+G ++ P + L I+ G + C + G A + L+++ P +
Sbjct: 1376 EGGQLPPGHSVQD-----GVLRIQNLDQSCQGTYICQAHGPWGKA-QASAQLVIQALPSV 1429
Query: 359 DTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITY 418
+ VG C P P TWSK G L + +
Sbjct: 1430 LINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL-------------RPGIVQS 1476
Query: 419 TSVLLINNVATSDYGSYECGARNELGFSTTTVKLDVTSAP 458
V+ I +V +D G Y C A N G + + V L V + P
Sbjct: 1477 GGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALP 1516
Score = 43.2 bits (97), Expect = 0.004
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 9/145 (6%)
Query: 13 MINSPSDPPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTTKTT 72
++++ + P AP + T+ AG L C +T G+P T+ W K+ S
Sbjct: 1141 IVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSAT-GSPAPTIHW----SKLRSPLPWQ 1195
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+ + I + QY C AT+ A T+ L+V P A V V +
Sbjct: 1196 YRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE--ATIILHVESPPYATTVPEHASV-QA 1252
Query: 133 GIEATLICDSASSNPPATLSWWRDG 157
G L C A PP T W R G
Sbjct: 1253 GETVQLQC-LAHGTPPLTFQWSRVG 1276
Score = 40.7 bits (91), Expect = 0.021
Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
I+ G ++ + + DAG Y C A N+ G +++ + V I S+ Q V
Sbjct: 1473 IVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQI-SMPQEVRVPAGSA 1531
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVN 337
AV C A G P I W + + P S + + L++ + ++ G + C
Sbjct: 1532 AVFPCIASGYP--TPDISWSKLDGSLPPDS-----RLENNMLMLPSVRPQDAGTYVCTAT 1584
Query: 338 NGIG 341
N G
Sbjct: 1585 NRQG 1588
Score = 37.9 bits (84), Expect = 0.15
Identities = 57/248 (22%), Positives = 89/248 (35%), Gaps = 45/248 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANI--------SVSVHYPA-------GIK 264
+ GS L + ++ D+G Y C + S G A++ S +VH PA I+
Sbjct: 713 TRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIE 772
Query: 265 SVSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKA 324
S V D L C G + W ++G + + P L + +
Sbjct: 773 PSSSRVAEGQTLD--LKCVVPGQ--AHAQVTWHKRGGNLPARHQVHGP-----LLRLNQV 823
Query: 325 KSENLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTSPNFVK------SASNV--GQVGR 376
+ G + C V G+ ++ I P +P + S+S+V GQ
Sbjct: 824 SPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLD 883
Query: 377 LMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYE 436
L C TW K G LP H T+ S L ++ V+ +D G Y
Sbjct: 884 LNCVVPGQAHAQVTWYKRGGSLPAR-------------HQTHGSQLRLHLVSPADSGEYV 930
Query: 437 CGARNELG 444
C A + G
Sbjct: 931 CRAASGPG 938
Score = 35.5 bits (78), Expect = 0.79
Identities = 76/327 (23%), Positives = 119/327 (36%), Gaps = 56/327 (17%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
+P + PI +++S V E + L ++ P +I TW K G S R
Sbjct: 565 VPSVSPPIRIESSSPTVV--EGQTLDLNCVVARQPQAII-TWYKRG--------GSLPSR 613
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKS 265
+ GS L + +++ D+G Y C A N+ A A+I +SV AG I+S
Sbjct: 614 HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIES 673
Query: 266 VSQNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAK 325
S +V D L+C G + W ++G S+ + S L +
Sbjct: 674 SSSHVAEGETLD--LNCVVPGQ--AHAQVTWHKRG-----GSLPSHHQTRGSRLRLHHVS 724
Query: 326 SENLGNFQCVVNNGIGSATKQDVMLI------VKFKPEMDTSP--NFVKSASNV--GQVG 375
+ G + C V G ++ I P +P S+S V GQ
Sbjct: 725 PADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTL 784
Query: 376 RLMCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSY 435
L C TW K G LP H + +L +N V+ +D G Y
Sbjct: 785 DLKCVVPGQAHAQVTWHKRGGNLPAR-------------HQVHGPLLRLNQVSPADSGEY 831
Query: 436 ECGARNELGFSTTTVKLDV-TSAPDQV 461
C G +V + + S+P +
Sbjct: 832 SCQVTGSSGTLEASVLVTIEPSSPGPI 858
Score = 33.5 bits (73), Expect = 3.2
Identities = 58/253 (22%), Positives = 95/253 (37%), Gaps = 48/253 (18%)
Query: 220 SEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAG------------IKSVS 267
+ GS+L + + + D+G Y C + S A++ V++ PAG I+S S
Sbjct: 327 THGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVPALGVTPTVRIESSS 385
Query: 268 QNVVANPNEDAVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSE 327
V D L+C G + W ++G + + S L + +
Sbjct: 386 SQVAEGQTLD--LNCLVAGQ--AHAQVTWHKRGGSLPARHQVH-----GSRLRLLQVTPA 436
Query: 328 NLGNFQCVVNNGIGSATKQDVMLIVKFKPEMDTS-------PNFVKSASNV---GQVGRL 377
+ G + C V +GS+ Q+ ++V + + S P ++S+S G L
Sbjct: 437 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 493
Query: 378 MCKCKSVPAPSFTWSKNGVKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGSYEC 437
C S + TW K G LP + H S L I V +D G Y C
Sbjct: 494 NCLVASQAPHTITWYKRGGSLP-------------SRHQIVGSRLRIPQVTPADSGEYVC 540
Query: 438 GARNELGFSTTTV 450
N G T++
Sbjct: 541 HVSNGAGSRETSL 553
>AB058770-1|BAB47496.1| 779|Homo sapiens KIAA1867 protein protein.
Length = 779
Score = 74.9 bits (176), Expect = 1e-12
Identities = 74/298 (24%), Positives = 131/298 (43%), Gaps = 30/298 (10%)
Query: 158 IPVQNAPIFDDTTSYNTVGIENEPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDR 217
I +Q+ P+ + + V +E+ + A NP Y W K G I ++S
Sbjct: 245 IDIQHPPLVNLSVEPQPV-LEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEAS------- 296
Query: 218 IISEGSMLNMTKLTRHDAGIYTCEAVNSQGAAVANISVSVHYPAGIKSVSQNVVANPNED 277
G + T + + +CE N+ G+ + +V V++ + + Q+++ + D
Sbjct: 297 ----GEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSD 352
Query: 278 AVLSCTAIGNPLLAEHIKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQC-VV 336
A+ SC GNP L I W ++G + V K LT ++ + E+ G + C V
Sbjct: 353 AIFSCAWTGNPSLT--IVWMKRGSGV----VLSNEKTLT----LKSVRQEDAGKYVCRAV 402
Query: 337 NNGIGSATKQDVMLIVKFKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPS-FTWSKNG 395
+G A +++V L V P + ++ + A + G+ G++ C +S P P WS
Sbjct: 403 VPRVG-AGEREVTLTVNGPPIISSTQ--TQHALH-GEKGQIKCFIRSTPPPDRIAWSWKE 458
Query: 396 VKLPVNTSTKYFAEFHKNDHITYTSVLLINNVATSDYGS-YECGARNELGFSTTTVKL 452
L TS +Y E + S L I+N+ +D+ + Y C A N G T ++L
Sbjct: 459 NVLESGTSGRYTVETISTEE-GVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRL 515
Score = 54.0 bits (124), Expect = 2e-06
Identities = 76/316 (24%), Positives = 122/316 (38%), Gaps = 41/316 (12%)
Query: 20 PPSAPMITGYVPGTTLAAGTVQKLACISTGGNPLATLTWFKNDKKIHSTT--KT-----T 72
PP P+I G P +L AG L C + P A++ W + + I+ T KT
Sbjct: 147 PPDDPVILGG-PVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGK 205
Query: 73 DKAVSAEISILTNVTDNQAQYRCEATNSATEIPLFETVTLNVHFAPEAVKVRAEPDVLKP 132
+++ + + I +N C ATN A +VT+++ P V + EP +
Sbjct: 206 RESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQH-PPLVNLSVEPQPVLE 264
Query: 133 GIEATLICDSASSNPPAT-LSWWRDGIPVQNA--PIFDDTTSY------------NTVGI 177
T C SA +NP T W + G ++ A ++ T Y N +G
Sbjct: 265 DNVVTFHC-SAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGS 323
Query: 178 ENEPLIISV----RADGNPPSITYTWTKDGL---------PITQSSYSSGNDRIISEGSM 224
N + V R P S+ D + +T G+ ++S
Sbjct: 324 TNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKT 383
Query: 225 LNMTKLTRHDAGIYTCEAVNSQ-GAAVANISVSVHYPAGIKSVSQNVVANPNEDAVLSCT 283
L + + + DAG Y C AV + GA ++++V+ P I S +Q A E + C
Sbjct: 384 LTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISS-TQTQHALHGEKGQIKCF 442
Query: 284 AIGNPLLAEHIKWERK 299
P + I W K
Sbjct: 443 IRSTP-PPDRIAWSWK 457
Score = 45.6 bits (103), Expect = 7e-04
Identities = 50/222 (22%), Positives = 86/222 (38%), Gaps = 19/222 (8%)
Query: 180 EPLIISVRADGNPPSITYTWTKDGLPITQSSYSSGNDRIISEGSMLNMTKLTRHD---AG 236
+PL ++ AD P+ + W + G I ++YS R S+++ ++ D
Sbjct: 165 DPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQ 224
Query: 237 IYTCEAVNS--QGAAVANISVSVHYPAGIK-SVSQNVVANPNEDAVLSCTAIGNPLLAEH 293
C A N G ++++ + +P + SV V N C+A NP + ++
Sbjct: 225 SIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNV-VTFHCSAKANPAVTQY 283
Query: 294 IKWERKGYKIDPKSVTFEPKNLTSYLIIRKAKSENLGNFQCVVNNGIGSATKQDVMLIVK 353
+W ++G I S + Y + S C V N +GS T + V
Sbjct: 284 -RWAKRGQIIKEASGEVY-RTTVDYTYFSEPVS-------CEVTNALGS-TNLSRTVDVY 333
Query: 354 FKPEMDTSPNFVKSASNVGQVGRLMCKCKSVPAPSFTWSKNG 395
F P M T P + ++G C P+ + W K G
Sbjct: 334 FGPRMTTEPQSL--LVDLGSDAIFSCAWTGNPSLTIVWMKRG 373
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.313 0.130 0.385
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 131,117,843
Number of Sequences: 224733
Number of extensions: 5871616
Number of successful extensions: 31838
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 422
Number of HSP's successfully gapped in prelim test: 1059
Number of HSP's that attempted gapping in prelim test: 19906
Number of HSP's gapped (non-prelim): 8475
length of query: 838
length of database: 73,234,838
effective HSP length: 96
effective length of query: 742
effective length of database: 51,660,470
effective search space: 38332068740
effective search space used: 38332068740
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 69 (31.9 bits)
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