Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000158-TA|BGIBMGA000158-PA|IPR000172|Glucose-methanol-
choline oxidoreductase, N-terminal, IPR007867|Glucose-methanol-choline
oxidoreductase, C-terminal, IPR012132|Glucose-methanol-choline
oxidoreductase
(564 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC034502-1|AAH34502.1| 594|Homo sapiens choline dehydrogenase p... 199 2e-50
AJ272267-1|CAB75961.1| 482|Homo sapiens choline dehydrogenase p... 184 6e-46
X82336-1|CAB94714.1| 1500|Homo sapiens Menkes disease protein. 32 6.2
U27381-1|AAA96010.1| 1447|Homo sapiens protein ( Human Menkes di... 32 6.2
L06133-1|AAA35580.1| 1500|Homo sapiens Cu++-transporting P-type ... 32 6.2
AL645821-1|CAI42806.1| 1500|Homo sapiens ATPase, Cu++ transporti... 32 6.2
>BC034502-1|AAH34502.1| 594|Homo sapiens choline dehydrogenase
protein.
Length = 594
Score = 199 bits (486), Expect = 2e-50
Identities = 174/561 (31%), Positives = 265/561 (47%), Gaps = 45/561 (8%)
Query: 27 DTFDFVVVGSG-CGAIVADRLSENSSVRVLLIEAGTYP--------SNESIMPGTFPLLQ 77
D + +VVVG+G G ++A RL+E+ + RVLL+EAG S + MP L+
Sbjct: 39 DEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVRAGSKRLSWKIHMPAA--LVA 96
Query: 78 NSYEDWNETSIPESTTKHQKIGAYKLSTGKALGGGSTINHLLHLRGDKDDFDTWASYLGD 137
N +D + G+ GG S++N ++++RG +D++ W G
Sbjct: 97 NLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQ-GA 155
Query: 138 DSWSSANVRKYFKKSENMLDADIMASHADYHGTEGPVMVSR-QPDDATH-NLLKAFSDIG 195
W A+ YF+K++ ++ AS Y G +GP+ VSR + + H L+A G
Sbjct: 156 RGWDYAHCLPYFRKAQGH---ELGASR--YRGADGPLRVSRGKTNHPLHCAFLEATQQAG 210
Query: 196 VPTVIDLNADDNVGCAEASYIIGDGVRQSTAYAYLNKK-TRDNLYVLTETLAEKIIIEND 254
P D+N G I +G R S A AYL+ +R NL ETL +++ E
Sbjct: 211 YPLTEDMNGFQQEGFGWMDMTIHEGKRWSAACAYLHPALSRTNLKAEAETLVSRVLFEGT 270
Query: 255 IAKGVILRLASGKKINVYASKEVIISAGSFNSPKILMLSGIGPADHLKSMGIDVIKDLP- 313
A GV + +G+ YASKEVI+S G+ NSP++LMLSGIG AD LK +GI V+ LP
Sbjct: 271 RAVGVEY-VKNGQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPG 329
Query: 314 VGQGMQDHNALFLVNKLEES-TATSETLPLTKFPFPILLASVNLDDSKSYADYLLIGLVF 372
VGQ +QDH +++ T S PL K I L + + +L G
Sbjct: 330 VGQNLQDHLEIYIQQACTRPITLHSAQKPLRK--VCIGLEWLWKFTGEGATAHLETGGFI 387
Query: 373 AQDKGYTDVTCSTLFSFTDEICSNFSESVAGRNQFISLIGTSQPKSRGYVQLKSSDPDDK 432
G F F + + + +G + S G+++L+S++P D
Sbjct: 388 RSQPGVPHPDIQ--FHFLPSQVIDHGRVPTQQEAYQVHVGPMRGTSVGWLKLRSANPQDH 445
Query: 433 LVISESFYS---DPEDFTNMLKYLTHFLTIYNSAYFQDIKAEIADPGLEECGEMDVSSED 489
VI ++ S D EDF +K LT I+ + + PG + S+
Sbjct: 446 PVIQPNYLSTETDIEDFRLCVK-LTR--EIFAQEALAPFRGKELQPG------SHIQSDK 496
Query: 490 YWKCYIKSMTVHLFHYSGTCAMG------SVVDSKMKVYGIDNLRVVDVSTMPFIVRANT 543
++++ +H S TC MG +VVD + +V G++NLRVVD S MP +V N
Sbjct: 497 EIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVSGNL 556
Query: 544 LAAGIMMAEKISDDIKNEYSL 564
A IM+AEK +D IK + +L
Sbjct: 557 NAPTIMIAEKAADIIKGQPAL 577
>AJ272267-1|CAB75961.1| 482|Homo sapiens choline dehydrogenase
protein.
Length = 482
Score = 184 bits (449), Expect = 6e-46
Identities = 150/473 (31%), Positives = 228/473 (48%), Gaps = 34/473 (7%)
Query: 106 GKALGGGSTINHLLHLRGDKDDFDTWASYLGDDSWSSANVRKYFKKSENMLDADIMASHA 165
G+ GG S++N ++++RG +D++ W G W A+ YF+K++ ++ AS
Sbjct: 13 GRVWGGSSSLNAMVYVRGHAEDYERWQRQ-GARGWDYAHCLPYFRKAQGH---ELGASR- 67
Query: 166 DYHGTEGPVMVSR-QPDDATH-NLLKAFSDIGVPTVIDLNADDNVGCAEASYIIGDGVRQ 223
Y G +GP+ VSR + + H L+A G P D+N G I +G R
Sbjct: 68 -YRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRW 126
Query: 224 STAYAYLNKK-TRDNLYVLTETLAEKIIIENDIAKGVILRLASGKKINVYASKEVIISAG 282
S A AYL+ +R NL ETL +++ E A GV + +G+ YASKEVI+S G
Sbjct: 127 SAACAYLHPALSRTNLKAEAETLVSRVLFEGTRAVGVEY-VKNGQSHRAYASKEVILSGG 185
Query: 283 SFNSPKILMLSGIGPADHLKSMGIDVIKDLP-VGQGMQDHNALFLVNKLEES-TATSETL 340
+ NSP++LMLSGIG AD LK +GI V+ LP VGQ +QDH +++ T S
Sbjct: 186 AINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTRPITLHSAQK 245
Query: 341 PLTKFPFPILLASVNLDDSKSYADYLLIGLVFAQDKGYTDVTCSTLFSFTDEICSNFSES 400
PL K I L + + +L G G F F +
Sbjct: 246 PLRK--VCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQ--FHFLPSQVIDHGRV 301
Query: 401 VAGRNQFISLIGTSQPKSRGYVQLKSSDPDDKLVISESFYS---DPEDFTNMLKYLTHFL 457
+ + +G + S G+++L+S++P D VI ++ S D EDF +K LT
Sbjct: 302 PTQQEAYQVHVGPMRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVK-LTR-- 358
Query: 458 TIYNSAYFQDIKAEIADPGLEECGEMDVSSEDYWKCYIKSMTVHLFHYSGTCAMG----- 512
I+ + + PG + S+ ++++ +H S TC MG
Sbjct: 359 EIFAQEALAPFRGKELQPG------SHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDP 412
Query: 513 -SVVDSKMKVYGIDNLRVVDVSTMPFIVRANTLAAGIMMAEKISDDIKNEYSL 564
+VVD + +V G++NLRVVD S MP +V N A IM+AEK +D IK + +L
Sbjct: 413 TAVVDPQTRVLGVENLRVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPAL 465
>X82336-1|CAB94714.1| 1500|Homo sapiens Menkes disease protein.
Length = 1500
Score = 31.9 bits (69), Expect = 6.2
Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 255 IAKGVILRLASGKKINVYASKEVIISAGSFNSPKILMLSGIGPADHLKSMGIDVIKDLPV 314
IAKG A K I++ A++ I++ S N ++LS L G D+IK +P
Sbjct: 800 IAKGKTSE-ALAKLISLQATEATIVTLDSDN----ILLSEEQVDVELVQRG-DIIKVVPG 853
Query: 315 GQGMQDHNALFLVNKLEESTATSETLPLTKFPFPILLA-SVNLDDS 359
G+ D + + ++ES T E +P+ K P ++A S+N + S
Sbjct: 854 GKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGS 899
>U27381-1|AAA96010.1| 1447|Homo sapiens protein ( Human Menkes
disease gene (ATP7A), partial exon 23, partial cds. ).
Length = 1447
Score = 31.9 bits (69), Expect = 6.2
Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 255 IAKGVILRLASGKKINVYASKEVIISAGSFNSPKILMLSGIGPADHLKSMGIDVIKDLPV 314
IAKG A K I++ A++ I++ S N ++LS L G D+IK +P
Sbjct: 800 IAKGKTSE-ALAKLISLQATEATIVTLDSDN----ILLSEEQVDVELVQRG-DIIKVVPG 853
Query: 315 GQGMQDHNALFLVNKLEESTATSETLPLTKFPFPILLA-SVNLDDS 359
G+ D + + ++ES T E +P+ K P ++A S+N + S
Sbjct: 854 GKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGS 899
>L06133-1|AAA35580.1| 1500|Homo sapiens Cu++-transporting P-type
ATPase protein.
Length = 1500
Score = 31.9 bits (69), Expect = 6.2
Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 255 IAKGVILRLASGKKINVYASKEVIISAGSFNSPKILMLSGIGPADHLKSMGIDVIKDLPV 314
IAKG A K I++ A++ I++ S N ++LS L G D+IK +P
Sbjct: 800 IAKGKTSE-ALAKLISLQATEATIVTLDSDN----ILLSEEQVDVELVQRG-DIIKVVPG 853
Query: 315 GQGMQDHNALFLVNKLEESTATSETLPLTKFPFPILLA-SVNLDDS 359
G+ D + + ++ES T E +P+ K P ++A S+N + S
Sbjct: 854 GKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGS 899
>AL645821-1|CAI42806.1| 1500|Homo sapiens ATPase, Cu++ transporting,
alpha polypeptide (Menkes syndrome) protein.
Length = 1500
Score = 31.9 bits (69), Expect = 6.2
Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 255 IAKGVILRLASGKKINVYASKEVIISAGSFNSPKILMLSGIGPADHLKSMGIDVIKDLPV 314
IAKG A K I++ A++ I++ S N ++LS L G D+IK +P
Sbjct: 800 IAKGKTSE-ALAKLISLQATEATIVTLDSDN----ILLSEEQVDVELVQRG-DIIKVVPG 853
Query: 315 GQGMQDHNALFLVNKLEESTATSETLPLTKFPFPILLA-SVNLDDS 359
G+ D + + ++ES T E +P+ K P ++A S+N + S
Sbjct: 854 GKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGS 899
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.316 0.134 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,992,422
Number of Sequences: 224733
Number of extensions: 3307406
Number of successful extensions: 8987
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 8976
Number of HSP's gapped (non-prelim): 9
length of query: 564
length of database: 73,234,838
effective HSP length: 94
effective length of query: 470
effective length of database: 52,109,936
effective search space: 24491669920
effective search space used: 24491669920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 68 (31.5 bits)
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