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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000155-TA|BGIBMGA000155-PA|IPR003521|Nucleotide-
sensitive chloride conductance regulator
         (201 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000519C17 Cluster: PREDICTED: similar to Methylosom...    95   1e-18
UniRef50_P54105 Cluster: Methylosome subunit pICln (Chloride con...    83   3e-15
UniRef50_UPI00015B5973 Cluster: PREDICTED: similar to MGC81186 p...    80   4e-14
UniRef50_UPI0000D55A72 Cluster: PREDICTED: similar to chloride c...    52   1e-05
UniRef50_Q965E1 Cluster: ICln2; n=3; Caenorhabditis|Rep: ICln2 -...    48   2e-04
UniRef50_A7RR20 Cluster: Predicted protein; n=1; Nematostella ve...    48   2e-04
UniRef50_Q9U3W1 Cluster: ICLn protein; n=4; Sophophora|Rep: ICLn...    44   0.002
UniRef50_A7QGR6 Cluster: Chromosome chr16 scaffold_94, whole gen...    41   0.024
UniRef50_UPI0001555F4F Cluster: PREDICTED: similar to chloride c...    40   0.031
UniRef50_Q54Q91 Cluster: Putative uncharacterized protein; n=1; ...    40   0.054
UniRef50_Q9LVA7 Cluster: Genomic DNA, chromosome 5, P1 clone:MMI...    39   0.072
UniRef50_UPI0000E48BE3 Cluster: PREDICTED: similar to swelling d...    39   0.095
UniRef50_A4A6X8 Cluster: Formyl transferase domain protein; n=1;...    34   2.7  
UniRef50_O61674 Cluster: Faint sausage; n=6; Diptera|Rep: Faint ...    33   3.6  
UniRef50_Q1B171 Cluster: NUDIX hydrolase; n=7; Mycobacterium|Rep...    33   6.2  
UniRef50_A0QRN8 Cluster: Serine esterase, cutinase family protei...    32   8.3  

>UniRef50_UPI0000519C17 Cluster: PREDICTED: similar to Methylosome
           subunit pICln (Chloride conductance regulatory protein
           ICln) (I(Cln)) (Chloride channel, nucleotide sensitive
           1A) (Chloride ion current inducer protein) (ClCI); n=1;
           Apis mellifera|Rep: PREDICTED: similar to Methylosome
           subunit pICln (Chloride conductance regulatory protein
           ICln) (I(Cln)) (Chloride channel, nucleotide sensitive
           1A) (Chloride ion current inducer protein) (ClCI) - Apis
           mellifera
          Length = 207

 Score = 94.7 bits (225), Expect = 1e-18
 Identities = 55/144 (38%), Positives = 81/144 (56%), Gaps = 10/144 (6%)

Query: 2   VVVSSNFAEPADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINL 61
           +VV SNF  P +G+  +  +T + IND+E+G  TLYITE+ + W    +  G      +L
Sbjct: 1   MVVLSNFLAPQEGIRHEEQNTTVYINDREVGKGTLYITESLLSWVNYDTQQG-----FSL 55

Query: 62  LYPSISLHAIQRE----PSPALYMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQL 117
            YP ISLHAI R+    P   LY++++ ++ LP++S    S              PIT++
Sbjct: 56  EYPHISLHAISRDEQVHPRQCLYIMVDAKVDLPDVSLSPASDSGSENEFEDADT-PITEM 114

Query: 118 RFIPENENELQAMYSAMCQGQELH 141
           RF P+N N L+AM+ AM Q Q LH
Sbjct: 115 RFAPDNTNNLEAMFQAMNQCQALH 138


>UniRef50_P54105 Cluster: Methylosome subunit pICln (Chloride
           conductance regulatory protein ICln) (I(Cln)); n=40;
           Euteleostomi|Rep: Methylosome subunit pICln (Chloride
           conductance regulatory protein ICln) (I(Cln)) - Homo
           sapiens (Human)
          Length = 237

 Score = 83.4 bits (197), Expect = 3e-15
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>UniRef50_UPI00015B5973 Cluster: PREDICTED: similar to MGC81186
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to MGC81186 protein - Nasonia vitripennis
          Length = 222

 Score = 79.8 bits (188), Expect = 4e-14
 Identities = 54/158 (34%), Positives = 80/158 (50%), Gaps = 23/158 (14%)

Query: 2   VVVSSNFAEPADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINL 61
           +VV SNF  P +G+  +   T L IND+E+G  TLYITE+ + W    +  G      +L
Sbjct: 1   MVVLSNFLAPQEGIRHEEQQTTLYINDREVGKGTLYITESLLSWVNNDTRQG-----FSL 55

Query: 62  LYPSISLHAIQRE----PSPALYMVLNYELRLPEL--------SQQAGST------XXXX 103
            YP ISLHAI R+    P   LY++++ ++  P+         S ++ +T          
Sbjct: 56  EYPHISLHAISRDEQVHPRQCLYVMVDAKVDFPDSPTLQSNNDSNESNNTNEKNNDDNDD 115

Query: 104 XXXXXXXXQPITQLRFIPENENELQAMYSAMCQGQELH 141
                    PIT++RF P+N N L AM+ AM + Q LH
Sbjct: 116 DSDDDDSDAPITEMRFAPDNTNSLDAMFQAMNECQALH 153


>UniRef50_UPI0000D55A72 Cluster: PREDICTED: similar to chloride
           channel, nucleotide-sensitive, 1A; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to chloride channel,
           nucleotide-sensitive, 1A - Tribolium castaneum
          Length = 201

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 37/142 (26%), Positives = 71/142 (50%), Gaps = 9/142 (6%)

Query: 1   MVVVSSNFAEPADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTIN 60
           MVVV+S F  P   + L+  +  ++++ ++LGT TL+++E  + W       G    +I 
Sbjct: 1   MVVVTS-FKPPESPIRLEQSNVVVILDKRDLGTGTLFVSERTLSW----QKDGTTGFSIE 55

Query: 61  LLYPSISLHAIQREPSPALYMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQP-ITQLRF 119
             Y ++SLHA+ ++P+      + Y L  P ++    +             +P +++L  
Sbjct: 56  --YYNVSLHAVSKDPNVCERECI-YILTDPHINLFGETDQRPANDDSDVESEPDLSELIL 112

Query: 120 IPENENELQAMYSAMCQGQELH 141
            PEN   +Q++Y A+   QEL+
Sbjct: 113 APENPTHVQSIYEAIKICQELN 134


>UniRef50_Q965E1 Cluster: ICln2; n=3; Caenorhabditis|Rep: ICln2 -
           Caenorhabditis elegans
          Length = 225

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 38/157 (24%), Positives = 74/157 (47%), Gaps = 24/157 (15%)

Query: 3   VVSSNFAEPADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLL 62
           ++ +  ++P +G+ L + + +       LG  TLYIT++ VIW    S +G      ++ 
Sbjct: 1   MILTEVSQPTEGIKLATTNVQAFFKIDSLGNGTLYITDSAVIWIS--SAAGTKG--FSVA 56

Query: 63  YPSISLHAIQRE----PSPALYMVLNYE-----------LR-LPELSQQAG----STXXX 102
           YP+I LHAI  +    PS  ++++++             LR + E  +Q G    +    
Sbjct: 57  YPAIVLHAISTDVSVFPSEHIFVMVDQRKSVRRRRRAPVLRTIQEDDEQRGLELAAAELE 116

Query: 103 XXXXXXXXXQPITQLRFIPENENELQAMYSAMCQGQE 139
                    +P  ++RF+P++++ L  +Y  +  GQE
Sbjct: 117 DEESDDDEEEPALEIRFVPDDKDSLSQIYHQIAVGQE 153


>UniRef50_A7RR20 Cluster: Predicted protein; n=1; Nematostella
          vectensis|Rep: Predicted protein - Nematostella
          vectensis
          Length = 199

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 10/90 (11%)

Query: 2  VVVSSNFAEPADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINL 61
          +VV S+F  P +G+L     T+  + D+ LG   LYI +  + W      S       +L
Sbjct: 1  MVVMSSFPPPTEGLLHVQADTQAFMQDRCLGNGVLYIAQERLSW------SNEQGQGFSL 54

Query: 62 LYPSISLHAIQRE----PSPALYMVLNYEL 87
           YPSIS+HAI R+    P   +Y +L+  L
Sbjct: 55 EYPSISVHAICRDTAKFPHQCIYCMLDSPL 84


>UniRef50_Q9U3W1 Cluster: ICLn protein; n=4; Sophophora|Rep: ICLn
          protein - Drosophila melanogaster (Fruit fly)
          Length = 215

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 5/86 (5%)

Query: 2  VVVSSNFAEPADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINL 61
          +V+  + + P  G+L  + + KL + D+ +G  T+YI +N + W     P+   A  I++
Sbjct: 1  MVLIMHVSPPEHGLLYTANNIKLKLGDKVVGEGTVYIAQNTLSW----QPT-ELAEGISI 55

Query: 62 LYPSISLHAIQREPSPALYMVLNYEL 87
           +  +SLH I   P   +Y +L++++
Sbjct: 56 EWKQVSLHGISSNPRKCIYFMLDHKV 81


>UniRef50_A7QGR6 Cluster: Chromosome chr16 scaffold_94, whole genome
           shotgun sequence; n=2; Magnoliophyta|Rep: Chromosome
           chr16 scaffold_94, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 230

 Score = 40.7 bits (91), Expect = 0.024
 Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 14/111 (12%)

Query: 35  TLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHAIQREP----SPALYMVLNYELRLP 90
           TL+I+   VIW   V  +   A  ++ L  S+SLHA+ R+P    SP +Y  +  E    
Sbjct: 50  TLFISTKQVIWLSDVDRAKGYA--VDFL--SVSLHAVSRDPEAYSSPCIYTQIETE---- 101

Query: 91  ELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQAMYSAMCQGQELH 141
                A S               IT++R +P + ++L+ ++   C   EL+
Sbjct: 102 --ENDADSEGSDSECDGTLDLSKITEMRLVPSDPSQLETLFEMFCGCAELN 150


>UniRef50_UPI0001555F4F Cluster: PREDICTED: similar to chloride
           channel, partial; n=1; Ornithorhynchus anatinus|Rep:
           PREDICTED: similar to chloride channel, partial -
           Ornithorhynchus anatinus
          Length = 278

 Score = 40.3 bits (90), Expect = 0.031
 Identities = 15/30 (50%), Positives = 23/30 (76%)

Query: 112 QPITQLRFIPENENELQAMYSAMCQGQELH 141
           +PI + RF+P + + L+AM+SAMC+ Q LH
Sbjct: 115 EPIAEFRFVPGDRSALEAMFSAMCECQALH 144


>UniRef50_Q54Q91 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 190

 Score = 39.5 bits (88), Expect = 0.054
 Identities = 34/150 (22%), Positives = 67/150 (44%), Gaps = 14/150 (9%)

Query: 1   MVVVSSNFAEPADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTIN 60
           MV +        + V     +T L I  Q LG   +Y+T  NV W   +S +     T N
Sbjct: 1   MVEIKDLLKTEDEEVFFDLDNTTLYIGSQSLGEGHIYVTNKNVHW---ISKNNITKYTFN 57

Query: 61  LLYPSISLHAI--QREPSPA-LYMVLNYELRLPELSQQAGSTXXXXXX------XXXXXX 111
             + SI L+A+  + +  P+ +Y  ++  + + E ++ +                     
Sbjct: 58  --FYSIGLNAVFSKTDEFPSSVYCQVDEIVTVAENNENSDKIKDEEDQDEDEENSGDVDD 115

Query: 112 QPITQLRFIPENENELQAMYSAMCQGQELH 141
              T++RFIP +++++ ++Y A+C+G  L+
Sbjct: 116 DVYTEIRFIPSDDSKIHSIYDALCKGALLN 145


>UniRef50_Q9LVA7 Cluster: Genomic DNA, chromosome 5, P1 clone:MMI9;
           n=3; Magnoliophyta|Rep: Genomic DNA, chromosome 5, P1
           clone:MMI9 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 229

 Score = 39.1 bits (87), Expect = 0.072
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 16/111 (14%)

Query: 35  TLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHAIQREP----SPALYMVLNYELRLP 90
           TLYIT   +IW   V  +   A  ++ L  SISLHA+ R+P    SP +Y  +  E    
Sbjct: 50  TLYITSRKLIWLSDVDMAKGYA--VDFL--SISLHAVSRDPEAYSSPCIYTQIEVE---- 101

Query: 91  ELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQAMYSAMCQGQELH 141
               +                  I ++R +P +  +L+ ++   C+  EL+
Sbjct: 102 ----EDEDDESDSESTEVLDLSKIREMRLVPSDSTQLETLFDVFCECAELN 148


>UniRef50_UPI0000E48BE3 Cluster: PREDICTED: similar to swelling
           dependent chloride channel, ICln; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           swelling dependent chloride channel, ICln -
           Strongylocentrotus purpuratus
          Length = 167

 Score = 38.7 bits (86), Expect = 0.095
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 12/102 (11%)

Query: 49  VSPSGNPAPTINLLYPSISLHAIQRE----PSPALYMVLNY----ELR-LPELSQQAGST 99
           ++PSG      N+ Y +I++HAI R+    P   LY++++     ELR +P         
Sbjct: 7   INPSGQG---FNIPYRAITVHAISRDLSSFPHECLYLMIDSDVMSELRDVPGHGGDGPQD 63

Query: 100 XXXXXXXXXXXXQPITQLRFIPENENELQAMYSAMCQGQELH 141
                         + ++R +P+++  LQ+M+ AM Q Q LH
Sbjct: 64  NNSDDGFEEEEGNEVREIRLVPQDKTMLQSMFEAMSQCQALH 105


>UniRef50_A4A6X8 Cluster: Formyl transferase domain protein; n=1;
           Congregibacter litoralis KT71|Rep: Formyl transferase
           domain protein - Congregibacter litoralis KT71
          Length = 268

 Score = 33.9 bits (74), Expect = 2.7
 Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 1/48 (2%)

Query: 24  LLINDQELGTATLYITENNVIWGGGVSPSGNP-APTINLLYPSISLHA 70
           +L  DQELGT   +I ++++  GG +S + NP  P  + L+  I+L+A
Sbjct: 153 MLAGDQELGTTLHFIEDSSIDTGGVISQTLNPLVPGKSYLWQVINLYA 200


>UniRef50_O61674 Cluster: Faint sausage; n=6; Diptera|Rep: Faint
           sausage - Drosophila melanogaster (Fruit fly)
          Length = 822

 Score = 33.5 bits (73), Expect = 3.6
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 6/68 (8%)

Query: 9   AEPADGVLLQSPSTK-LLINDQELGTATLYIT--ENNVIWGGGVSPSGNPAPTIN---LL 62
           A P   V+L  P    LLI+ + L  + L++   EN+ +    VS  GNP PT+    LL
Sbjct: 325 ARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTLTWEVLL 384

Query: 63  YPSISLHA 70
            P +  HA
Sbjct: 385 SPGVDRHA 392


>UniRef50_Q1B171 Cluster: NUDIX hydrolase; n=7; Mycobacterium|Rep:
           NUDIX hydrolase - Mycobacterium sp. (strain MCS)
          Length = 240

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 14  GVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHAIQR 73
           GV L   S   L++D    T + Y+    V+WGGG      PAP   +    + LH +QR
Sbjct: 124 GVALPDTSVLGLLDDYP--TRSGYVITPVVVWGGGRLDL-RPAPDEVVAAYRVGLHQLQR 180

Query: 74  EPSP 77
           + SP
Sbjct: 181 DDSP 184


>UniRef50_A0QRN8 Cluster: Serine esterase, cutinase family protein;
           n=1; Mycobacterium smegmatis str. MC2 155|Rep: Serine
           esterase, cutinase family protein - Mycobacterium
           smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 292

 Score = 32.3 bits (70), Expect = 8.3
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 20  PSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHAIQREPSPAL 79
           P TK+++     G A +    ++ +   GVSP+  PAP    +   ++  A+  +PSP  
Sbjct: 102 PDTKMVLGGFSQGAAVMGFVTSSAV-PDGVSPTEVPAPMPPEIADHVAAVALFGKPSPRF 160

Query: 80  YMVLN 84
             VLN
Sbjct: 161 MRVLN 165


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.314    0.133    0.387 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 185,858,983
Number of Sequences: 1657284
Number of extensions: 6277443
Number of successful extensions: 8810
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 8787
Number of HSP's gapped (non-prelim): 20
length of query: 201
length of database: 575,637,011
effective HSP length: 97
effective length of query: 104
effective length of database: 414,880,463
effective search space: 43147568152
effective search space used: 43147568152
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)
S2: 70 (32.3 bits)

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