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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000155-TA|BGIBMGA000155-PA|IPR003521|Nucleotide-
sensitive chloride conductance regulator
         (201 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X91788-1|CAA62902.1|  237|Homo sapiens Icln protein protein.           83   5e-16
U53454-1|AAB03316.1|  237|Homo sapiens chloride ion current indu...    83   5e-16
U17899-1|AAC50111.1|  237|Homo sapiens chloride channel regulato...    83   5e-16
BT019907-1|AAV38710.1|  237|Homo sapiens chloride channel, nucle...    83   5e-16
BC119635-1|AAI19636.1|  237|Homo sapiens chloride channel, nucle...    83   5e-16
BC119634-1|AAI19635.1|  237|Homo sapiens chloride channel, nucle...    83   5e-16
AF232708-1|AAF76861.1|  237|Homo sapiens chloride ion current in...    83   5e-16
AF232224-1|AAF76858.1|  237|Homo sapiens chloride ion current in...    83   5e-16
AF026003-1|AAB88806.1|  237|Homo sapiens chloride ion current in...    83   5e-16
AF005422-1|AAB61444.1|  237|Homo sapiens reticulocyte pICln prot...    83   5e-16
AF232225-1|AAF76859.1|  237|Homo sapiens chloride ion current in...    83   6e-16
BC060866-1|AAH60866.1|  995|Homo sapiens ankyrin repeat domain 3...    32   1.2  
AL832644-1|CAD89966.1|  704|Homo sapiens hypothetical protein pr...    32   1.2  
AL162739-5|CAI19298.1|  995|Homo sapiens novel protein protein.        32   1.2  
AL139343-4|CAI19093.1|  995|Homo sapiens novel protein protein.        32   1.2  
AJ550917-1|CAD80221.1|  131|Homo sapiens immunoglobulin heavy ch...    31   3.6  

>X91788-1|CAA62902.1|  237|Homo sapiens Icln protein protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>U53454-1|AAB03316.1|  237|Homo sapiens chloride ion current inducer
           protein protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>U17899-1|AAC50111.1|  237|Homo sapiens chloride channel regulatory
           protein protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>BT019907-1|AAV38710.1|  237|Homo sapiens chloride channel,
           nucleotide-sensitive, 1A protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>BC119635-1|AAI19636.1|  237|Homo sapiens chloride channel,
           nucleotide-sensitive, 1A protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>BC119634-1|AAI19635.1|  237|Homo sapiens chloride channel,
           nucleotide-sensitive, 1A protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>AF232708-1|AAF76861.1|  237|Homo sapiens chloride ion current
           inducer protein I(Cln) protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>AF232224-1|AAF76858.1|  237|Homo sapiens chloride ion current
           inducer protein I(Cln) protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>AF026003-1|AAB88806.1|  237|Homo sapiens chloride ion current
           inducer protein protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>AF005422-1|AAB61444.1|  237|Homo sapiens reticulocyte pICln
           protein.
          Length = 237

 Score = 83.4 bits (197), Expect = 5e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>AF232225-1|AAF76859.1|  237|Homo sapiens chloride ion current
           inducer protein I(Cln) protein.
          Length = 237

 Score = 83.0 bits (196), Expect = 6e-16
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 10/133 (7%)

Query: 11  PADGVLLQSPSTKLLINDQELGTATLYITENNVIWGGGVSPSGNPAPTINLLYPSISLHA 70
           PA+G+L Q P T+ ++N + LGT TLYI E+ + W  G S  G      +L YP+ISLHA
Sbjct: 12  PAEGLLRQHPDTEAVLNGKGLGTGTLYIAESRLSWLDG-SGLG-----FSLEYPTISLHA 65

Query: 71  IQREPSPAL--YMVLNYELRLPELSQQAGSTXXXXXXXXXXXXQPITQLRFIPENENELQ 128
           + R+ S  L  ++ +    +  E S++                +PIT+ RF+P +++ L+
Sbjct: 66  LSRDRSDCLGEHLYVMVNAKFEEESKE--PVADEEEEDSDDDVEPITEFRFVPSDKSALE 123

Query: 129 AMYSAMCQGQELH 141
           AM++AMC+ Q LH
Sbjct: 124 AMFTAMCECQALH 136


>BC060866-1|AAH60866.1|  995|Homo sapiens ankyrin repeat domain 38
           protein.
          Length = 995

 Score = 32.3 bits (70), Expect = 1.2
 Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 40  ENNVIWGGGVSPSGNPAPTINLLYPSISL-HAIQREPSPALYMVLNYELRLPEL-SQQAG 97
           EN ++WG      GN +P   +L P +SL    ++  + +++  L+ ELR+ E  ++Q G
Sbjct: 451 ENGLLWGPDGHKQGNQSPAERVLLPQLSLPQGPEQVLTSSVHSFLSTELRIEEAGTEQEG 510


>AL832644-1|CAD89966.1|  704|Homo sapiens hypothetical protein
           protein.
          Length = 704

 Score = 32.3 bits (70), Expect = 1.2
 Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 40  ENNVIWGGGVSPSGNPAPTINLLYPSISL-HAIQREPSPALYMVLNYELRLPEL-SQQAG 97
           EN ++WG      GN +P   +L P +SL    ++  + +++  L+ ELR+ E  ++Q G
Sbjct: 160 ENGLLWGPDGHKQGNQSPAERVLLPQLSLPQGPEQVLTSSVHSFLSTELRIEEAGTEQEG 219


>AL162739-5|CAI19298.1|  995|Homo sapiens novel protein protein.
          Length = 995

 Score = 32.3 bits (70), Expect = 1.2
 Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 40  ENNVIWGGGVSPSGNPAPTINLLYPSISL-HAIQREPSPALYMVLNYELRLPEL-SQQAG 97
           EN ++WG      GN +P   +L P +SL    ++  + +++  L+ ELR+ E  ++Q G
Sbjct: 451 ENGLLWGPDGHKQGNQSPAERVLLPQLSLPQGPEQVLTSSVHSFLSTELRIEEAGTEQEG 510


>AL139343-4|CAI19093.1|  995|Homo sapiens novel protein protein.
          Length = 995

 Score = 32.3 bits (70), Expect = 1.2
 Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 40  ENNVIWGGGVSPSGNPAPTINLLYPSISL-HAIQREPSPALYMVLNYELRLPEL-SQQAG 97
           EN ++WG      GN +P   +L P +SL    ++  + +++  L+ ELR+ E  ++Q G
Sbjct: 451 ENGLLWGPDGHKQGNQSPAERVLLPQLSLPQGPEQVLTSSVHSFLSTELRIEEAGTEQEG 510


>AJ550917-1|CAD80221.1|  131|Homo sapiens immunoglobulin heavy chain
           variable region protein.
          Length = 131

 Score = 30.7 bits (66), Expect = 3.6
 Identities = 13/44 (29%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 18  QSPSTKLLINDQELGTATLYI--TENNVIWGGGVSPSGNPAPTI 59
           +SP T+L I  +ELG   + +  T  + +W  G     +P+P +
Sbjct: 87  ESPKTRLCITVRELGVGDIVVVVTATHTVWTSGAKGPRSPSPEV 130


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.314    0.133    0.387 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 25,996,735
Number of Sequences: 224733
Number of extensions: 936562
Number of successful extensions: 1096
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1062
Number of HSP's gapped (non-prelim): 16
length of query: 201
length of database: 73,234,838
effective HSP length: 86
effective length of query: 115
effective length of database: 53,907,800
effective search space: 6199397000
effective search space used: 6199397000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)
S2: 63 (29.5 bits)

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