Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000152-TA|BGIBMGA000152-PA|IPR011009|Protein
kinase-like, IPR002172|Low density lipoprotein-receptor, class A,
IPR000998|MAM, IPR000719|Protein kinase, IPR008266|Tyrosine protein
kinase, active site, IPR001245|Tyrosine protein kinase
(1116 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D57520 Cluster: PREDICTED: similar to CG8250-PA;... 917 0.0
UniRef50_Q7KJ08 Cluster: Receptor protein tyrosine kinase ALK sp... 517 e-145
UniRef50_UPI00015B5971 Cluster: PREDICTED: similar to leukocyte ... 465 e-129
UniRef50_UPI0000DB6D22 Cluster: PREDICTED: similar to Alk CG8250... 435 e-120
UniRef50_Q4SK07 Cluster: Tyrosine-protein kinase receptor; n=2; ... 348 4e-94
UniRef50_UPI0000F2052A Cluster: PREDICTED: similar to anaplastic... 345 4e-93
UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; ... 345 5e-93
UniRef50_Q9UM73 Cluster: ALK tyrosine kinase receptor precursor;... 345 5e-93
UniRef50_Q8JFV0 Cluster: Tyrosine-protein kinase receptor; n=5; ... 339 2e-91
UniRef50_A6NNJ8 Cluster: Uncharacterized protein LTK; n=12; Euar... 328 4e-88
UniRef50_P08923 Cluster: Leukocyte tyrosine kinase receptor prec... 326 2e-87
UniRef50_P00529 Cluster: Tyrosine-protein kinase transforming pr... 287 2e-75
UniRef50_UPI0000DB6C99 Cluster: PREDICTED: similar to proto-onco... 276 2e-72
UniRef50_Q170Z1 Cluster: Tyrosine-protein kinase receptor; n=1; ... 274 1e-71
UniRef50_P08922 Cluster: Proto-oncogene tyrosine-protein kinase ... 269 2e-70
UniRef50_UPI0000E471D0 Cluster: PREDICTED: similar to p80 protei... 268 4e-70
UniRef50_Q5TUS8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 257 1e-66
UniRef50_O76411 Cluster: Suppressor of constitutive dauer format... 256 3e-66
UniRef50_Q9Y1Y9 Cluster: Protein tyrosine kinase; n=3; Metazoa|R... 254 1e-65
UniRef50_O76148 Cluster: Tyrosine-protein kinase receptor; n=1; ... 248 7e-64
UniRef50_P06213 Cluster: Insulin receptor precursor (EC 2.7.10.1... 243 2e-62
UniRef50_P13368 Cluster: Protein sevenless; n=20; Eumetazoa|Rep:... 243 2e-62
UniRef50_O73798 Cluster: Insulin-like growth factor 1 receptor p... 240 2e-61
UniRef50_P08069 Cluster: Insulin-like growth factor 1 receptor p... 237 9e-61
UniRef50_Q9PVZ4 Cluster: Insulin receptor precursor (EC 2.7.10.1... 236 3e-60
UniRef50_Q25410 Cluster: Putative molluscan insulin-related pept... 235 5e-60
UniRef50_P14616 Cluster: Insulin receptor-related protein precur... 232 5e-59
UniRef50_UPI0000D57494 Cluster: PREDICTED: similar to insulin re... 229 3e-58
UniRef50_Q7YT64 Cluster: Tyrosine-protein kinase receptor; n=1; ... 229 3e-58
UniRef50_Q25197 Cluster: Putative insulin-like peptide receptor ... 225 5e-57
UniRef50_UPI00015B5959 Cluster: PREDICTED: similar to insulin re... 225 7e-57
UniRef50_UPI0000DB6DD4 Cluster: PREDICTED: similar to Insulin-li... 223 3e-56
UniRef50_Q93105 Cluster: Insulin-like receptor precursor (EC 2.7... 222 4e-56
UniRef50_P09208 Cluster: Insulin-like receptor precursor (EC 2.7... 222 5e-56
UniRef50_Q9U5A8 Cluster: Insulin receptor-like protein precursor... 220 1e-55
UniRef50_O02466 Cluster: Insulin-like peptide receptor precursor... 220 2e-55
UniRef50_O97191 Cluster: Tyrosine-protein kinase receptor; n=1; ... 219 3e-55
UniRef50_Q4RM64 Cluster: Chromosome 10 SCAF15019, whole genome s... 219 5e-55
UniRef50_Q52V39 Cluster: Tyrosine-protein kinase receptor; n=2; ... 218 6e-55
UniRef50_Q2LC18 Cluster: Tyrosine-protein kinase receptor; n=2; ... 218 8e-55
UniRef50_Q7Q0F6 Cluster: Tyrosine-protein kinase receptor; n=2; ... 215 7e-54
UniRef50_Q5IJ68 Cluster: Trk-like receptor tyrosine kinase; n=1;... 215 7e-54
UniRef50_UPI0000D55DFF Cluster: PREDICTED: similar to Insulin-li... 214 1e-53
UniRef50_UPI0000D5603D Cluster: PREDICTED: similar to Insulin re... 209 4e-52
UniRef50_Q7Q5T3 Cluster: Tyrosine-protein kinase receptor; n=3; ... 208 9e-52
UniRef50_Q17JW1 Cluster: Tyrosine protein kinase; n=2; Culicidae... 204 1e-50
UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2; ... 202 3e-50
UniRef50_Q24488 Cluster: Tyrosine-protein kinase transmembrane r... 202 3e-50
UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 200 2e-49
UniRef50_P04629 Cluster: High affinity nerve growth factor recep... 199 3e-49
UniRef50_Q8JG38 Cluster: Fibroblast growth factor receptor 2 pre... 199 3e-49
UniRef50_Q91987 Cluster: BDNF/NT-3 growth factors receptor precu... 199 4e-49
UniRef50_UPI0000DB7F8D Cluster: PREDICTED: similar to Cad96Ca CG... 198 5e-49
UniRef50_Q9GRH2 Cluster: Tyrosine-protein kinase receptor; n=1; ... 198 5e-49
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 198 5e-49
UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Eu... 197 2e-48
UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precurso... 197 2e-48
UniRef50_Q16620 Cluster: BDNF/NT-3 growth factors receptor precu... 196 3e-48
UniRef50_Q3TJ05 Cluster: 14 days pregnant adult female placenta ... 194 8e-48
UniRef50_Q4H3B8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 194 8e-48
UniRef50_Q8IXC7 Cluster: Isoform of FGFR2; n=23; Euteleostomi|Re... 194 8e-48
UniRef50_Q2VXS7 Cluster: Proto-oncogene c-fes variant 4; n=77; E... 194 8e-48
UniRef50_P11362 Cluster: Basic fibroblast growth factor receptor... 194 1e-47
UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whol... 194 1e-47
UniRef50_P22182 Cluster: Fibroblast growth factor receptor 1 pre... 193 2e-47
UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot... 193 3e-47
UniRef50_UPI0000DB6B52 Cluster: PREDICTED: similar to Ror CG4926... 192 5e-47
UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular ... 192 5e-47
UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome sh... 191 8e-47
UniRef50_Q9VBW3 Cluster: Tyrosine kinase receptor Cad96Ca precur... 191 8e-47
UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4 var... 191 1e-46
UniRef50_A3EXK5 Cluster: Fibroblast growth factor receptor b; n=... 190 1e-46
UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot... 190 1e-46
UniRef50_UPI0000E47068 Cluster: PREDICTED: similar to tyrosine p... 190 2e-46
UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase recepto... 190 2e-46
UniRef50_O76997 Cluster: Putative neurotrophin receptor LTRK 1 p... 190 2e-46
UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4 pre... 190 2e-46
UniRef50_UPI0000DB7735 Cluster: PREDICTED: similar to Insulin re... 188 7e-46
UniRef50_UPI00004D7E5F Cluster: Proto-oncogene tyrosine-protein ... 188 7e-46
UniRef50_Q7YXV8 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 188 1e-45
UniRef50_P30530 Cluster: Tyrosine-protein kinase receptor UFO pr... 188 1e-45
UniRef50_Q86PM4 Cluster: Fibroblast growth factor receptor precu... 188 1e-45
UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; ... 187 2e-45
UniRef50_Q1JUB8 Cluster: Fibroblast growth factor receptor; n=2;... 187 2e-45
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 187 2e-45
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 186 2e-45
UniRef50_Q9Y1Y7 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 186 4e-45
UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane r... 186 4e-45
UniRef50_UPI00015B51DA Cluster: PREDICTED: similar to ENSANGP000... 184 9e-45
UniRef50_Q9Y1Y5 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 184 9e-45
UniRef50_Q26614 Cluster: Fibroblast growth factor receptor precu... 184 9e-45
UniRef50_Q9GRH1 Cluster: Tyrosine-protein kinase receptor; n=4; ... 184 1e-44
UniRef50_Q5I4E2 Cluster: Bm-DAF-2 precursor; n=1; Brugia malayi|... 184 1e-44
UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane r... 184 1e-44
UniRef50_Q16288 Cluster: NT-3 growth factor receptor precursor; ... 184 1e-44
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 183 2e-44
UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,... 183 3e-44
UniRef50_UPI0000D55449 Cluster: PREDICTED: similar to CG7223-PA,... 183 3e-44
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 183 3e-44
UniRef50_Q7PYY7 Cluster: ENSANGP00000019144; n=1; Anopheles gamb... 182 5e-44
UniRef50_Q6TYB9 Cluster: Dauer abnormal formation-2 precursor; n... 182 6e-44
UniRef50_Q95YM9 Cluster: Fibroblast growth factor receptor precu... 182 6e-44
UniRef50_Q7Z1D3 Cluster: Focal adhesion kinase; n=1; Lytechinus ... 181 8e-44
UniRef50_UPI00004D86FC Cluster: Tyrosine-protein kinase Tec (EC ... 181 1e-43
UniRef50_Q9Y1Y3 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 181 1e-43
UniRef50_Q008W6 Cluster: Gamma-carboxyglutamic acid protein 1; n... 181 1e-43
UniRef50_A7RZ71 Cluster: Predicted protein; n=1; Nematostella ve... 179 3e-43
UniRef50_A3EXK4 Cluster: Fibroblast growth factor receptor a; n=... 179 3e-43
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 179 5e-43
UniRef50_UPI00015A7C25 Cluster: UPI00015A7C25 related cluster; n... 179 5e-43
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 179 5e-43
UniRef50_Q12866 Cluster: Proto-oncogene tyrosine-protein kinase ... 179 5e-43
UniRef50_Q70W11 Cluster: Receptor tyrosine kinase X; n=1; Ciona ... 178 6e-43
UniRef50_UPI0000D569CE Cluster: PREDICTED: similar to CG10023-PA... 178 8e-43
UniRef50_Q7YSY1 Cluster: Fes-like tyrosine kinase protein; n=1; ... 177 1e-42
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 177 1e-42
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 177 1e-42
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 177 1e-42
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 177 2e-42
UniRef50_Q05397 Cluster: Focal adhesion kinase 1; n=111; Euteleo... 177 2e-42
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 177 2e-42
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 177 2e-42
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 176 2e-42
UniRef50_Q2VJ45 Cluster: HOOK3-RET fusion protein; n=3; Eutheria... 176 2e-42
UniRef50_P07949 Cluster: Proto-oncogene tyrosine-protein kinase ... 176 2e-42
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 176 2e-42
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 176 2e-42
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 176 3e-42
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 176 3e-42
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 175 4e-42
UniRef50_UPI00015B4CAE Cluster: PREDICTED: similar to ENSANGP000... 175 6e-42
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 175 6e-42
UniRef50_Q8INU0 Cluster: CG14396-PD, isoform D; n=10; Sophophora... 175 7e-42
UniRef50_Q10656-2 Cluster: Isoform b of Q10656 ; n=4; Caenorhabd... 174 1e-41
UniRef50_Q10656 Cluster: Myoblast growth factor receptor egl-15 ... 174 1e-41
UniRef50_Q7YZH7 Cluster: MBRTK2; n=1; Monosiga brevicollis|Rep: ... 174 1e-41
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 173 2e-41
UniRef50_UPI0000F2DD16 Cluster: PREDICTED: similar to cellular-r... 173 2e-41
UniRef50_Q4SQ93 Cluster: Tyrosine-protein kinase receptor; n=2; ... 173 2e-41
UniRef50_Q4RJ67 Cluster: Chromosome 1 SCAF15039, whole genome sh... 173 2e-41
UniRef50_Q9BLY1 Cluster: Receptor tyrosine kinase; n=5; Caenorha... 173 2e-41
UniRef50_Q7YZW6 Cluster: Putative uncharacterized protein; n=3; ... 173 2e-41
UniRef50_Q70W12 Cluster: Discoidin receptor; n=1; Ciona intestin... 173 2e-41
UniRef50_A7RNB1 Cluster: Predicted protein; n=1; Nematostella ve... 173 2e-41
UniRef50_A7RHT9 Cluster: Predicted protein; n=1; Nematostella ve... 173 2e-41
UniRef50_UPI0000E4736E Cluster: PREDICTED: similar to src-family... 173 3e-41
UniRef50_Q4RPK6 Cluster: Chromosome 12 SCAF15007, whole genome s... 173 3e-41
UniRef50_P79950 Cluster: Tyrosine kinase receptor; n=3; Xenopus|... 173 3e-41
UniRef50_Q7PWP1 Cluster: ENSANGP00000013218; n=2; Culicidae|Rep:... 173 3e-41
UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole... 172 4e-41
UniRef50_UPI0000D57178 Cluster: PREDICTED: similar to CG14396-PA... 172 5e-41
UniRef50_Q8WRF4 Cluster: Receptor tyrosine kinase; n=1; Monosiga... 172 5e-41
UniRef50_P08581 Cluster: Hepatocyte growth factor receptor precu... 171 7e-41
UniRef50_Q14289 Cluster: Protein tyrosine kinase 2 beta; n=47; E... 171 7e-41
UniRef50_Q0P4R9 Cluster: Discoidin domain receptor family, membe... 171 9e-41
UniRef50_Q5MCM8 Cluster: Protein-tyrosine kinase; n=2; Anthomedu... 171 9e-41
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 171 9e-41
UniRef50_Q16832 Cluster: Discoidin domain-containing receptor 2 ... 171 9e-41
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 170 2e-40
UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4; Endoptery... 170 2e-40
UniRef50_Q8MY85 Cluster: Fibroblast growth factor receptor 2 pre... 170 2e-40
UniRef50_UPI0000E49FB6 Cluster: PREDICTED: similar to RE05926p, ... 169 3e-40
UniRef50_Q64GK4 Cluster: C-Met receptor tyrosine kinase; n=9; Cl... 169 4e-40
UniRef50_Q8MY86 Cluster: Fibroblast growth factor receptor 1 pre... 169 4e-40
UniRef50_Q9YI66 Cluster: Developmental receptor tyrosine kinase;... 169 5e-40
UniRef50_P21709 Cluster: Ephrin type-A receptor 1 precursor; n=1... 169 5e-40
UniRef50_Q5RIU8 Cluster: Novel protein similar to vertebrate dis... 168 6e-40
UniRef50_Q06418 Cluster: Tyrosine-protein kinase receptor TYRO3 ... 168 6e-40
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 168 6e-40
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 168 6e-40
UniRef50_Q01974 Cluster: Tyrosine-protein kinase transmembrane r... 168 8e-40
UniRef50_P29317 Cluster: Ephrin type-A receptor 2 precursor; n=3... 168 8e-40
UniRef50_O16131 Cluster: Insulin receptor homolog precursor; n=2... 167 1e-39
UniRef50_UPI00015A61DF Cluster: UPI00015A61DF related cluster; n... 167 2e-39
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 166 3e-39
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 166 3e-39
UniRef50_Q98TD0 Cluster: Ephrin receptor; n=6; Amniota|Rep: Ephr... 166 3e-39
UniRef50_Q95ZV7 Cluster: Putative uncharacterized protein; n=3; ... 166 3e-39
UniRef50_Q8WSM2 Cluster: Receptor tyrosine kinase; n=1; Schistos... 166 3e-39
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 165 5e-39
UniRef50_Q09147 Cluster: Fibroblast growth factor receptor homol... 165 5e-39
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 165 6e-39
UniRef50_A7SFD8 Cluster: Predicted protein; n=2; Nematostella ve... 165 6e-39
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 165 8e-39
UniRef50_Q4RWP2 Cluster: Tyrosine-protein kinase receptor; n=1; ... 164 1e-38
UniRef50_Q70W09 Cluster: Receptor tyrosine kinase VIII; n=1; Cio... 164 1e-38
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 164 1e-38
UniRef50_Q4RY69 Cluster: Chromosome 3 SCAF14978, whole genome sh... 164 1e-38
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 164 1e-38
UniRef50_P23049 Cluster: Tyrosine-protein kinase transforming pr... 164 1e-38
UniRef50_A7S4Y9 Cluster: Predicted protein; n=1; Nematostella ve... 163 2e-38
UniRef50_P35590 Cluster: Tyrosine-protein kinase receptor Tie-1 ... 163 2e-38
UniRef50_UPI0000E49AA5 Cluster: PREDICTED: similar to leukocyte ... 163 2e-38
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 163 2e-38
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 163 3e-38
UniRef50_A7RGW8 Cluster: Predicted protein; n=1; Nematostella ve... 163 3e-38
UniRef50_Q95YD4 Cluster: Protein kinase protein 32, isoform a; n... 162 4e-38
UniRef50_Q02763 Cluster: Angiopoietin-1 receptor precursor; n=41... 162 4e-38
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 162 4e-38
UniRef50_P04626 Cluster: Receptor tyrosine-protein kinase erbB-2... 162 6e-38
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 161 7e-38
UniRef50_A7RVU0 Cluster: Predicted protein; n=1; Nematostella ve... 161 7e-38
UniRef50_Q07407 Cluster: Fibroblast growth factor receptor homol... 161 7e-38
UniRef50_UPI000065F6B2 Cluster: Receptor tyrosine-protein kinase... 161 1e-37
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 161 1e-37
UniRef50_A1IKE0 Cluster: Receptor tyrosine kinase-like orphan re... 161 1e-37
UniRef50_Q9YGM5 Cluster: Plasminogen related growth factor recep... 161 1e-37
UniRef50_Q15303 Cluster: Receptor tyrosine-protein kinase erbB-4... 161 1e-37
UniRef50_Q4SQX3 Cluster: Chromosome 11 SCAF14528, whole genome s... 160 2e-37
UniRef50_Q9Y1X8 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 160 2e-37
UniRef50_Q23554 Cluster: Putative uncharacterized protein; n=1; ... 160 2e-37
UniRef50_A7SZN9 Cluster: Predicted protein; n=3; Nematostella ve... 160 2e-37
UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; ... 160 2e-37
UniRef50_Q6DTW4 Cluster: Tyrosine kinase receptor ron; n=6; Eume... 160 2e-37
UniRef50_Q9N3S5 Cluster: Putative uncharacterized protein; n=4; ... 160 2e-37
UniRef50_Q86LZ8 Cluster: Insulin receptor protein kinase; n=2; S... 160 2e-37
UniRef50_Q674V1 Cluster: Vascular endothelial growth factor rece... 160 2e-37
UniRef50_Q5K4G5 Cluster: Receptor tyrosine kinase; n=1; Suberite... 160 2e-37
UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle spe... 159 3e-37
UniRef50_Q6PFV6 Cluster: Ephrin receptor; n=11; Tetrapoda|Rep: E... 159 4e-37
UniRef50_A7SL46 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 159 4e-37
UniRef50_A7S934 Cluster: Predicted protein; n=4; Nematostella ve... 159 5e-37
UniRef50_Q15516 Cluster: Tyrosine kinase; n=1; Homo sapiens|Rep:... 159 5e-37
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 159 5e-37
UniRef50_UPI00015B4B9F Cluster: PREDICTED: similar to prenylcyst... 158 7e-37
UniRef50_UPI0000E47549 Cluster: PREDICTED: similar to Cek8; n=2;... 158 7e-37
UniRef50_Q9V4E5 Cluster: CG1511-PC, isoform C; n=12; Diptera|Rep... 158 7e-37
UniRef50_Q61G93 Cluster: Putative uncharacterized protein CBG113... 158 7e-37
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 158 7e-37
UniRef50_P54756 Cluster: Ephrin type-A receptor 5 precursor; n=1... 158 7e-37
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 158 9e-37
UniRef50_Q68KJ7 Cluster: HER2; n=3; Amniota|Rep: HER2 - Felis si... 158 9e-37
UniRef50_Q08345 Cluster: Epithelial discoidin domain-containing ... 158 9e-37
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 157 1e-36
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 157 1e-36
UniRef50_Q8I7I5 Cluster: Roller: helically twisted, animals roll... 157 2e-36
UniRef50_Q04912 Cluster: Macrophage-stimulating protein receptor... 157 2e-36
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 157 2e-36
UniRef50_Q7Z1L9 Cluster: Neurite outgrowth regulated kinase; n=1... 157 2e-36
UniRef50_P04412 Cluster: Epidermal growth factor receptor precur... 157 2e-36
UniRef50_UPI0000E47A46 Cluster: PREDICTED: similar to ret protei... 156 3e-36
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 156 3e-36
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 156 4e-36
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 155 5e-36
UniRef50_Q4H3N2 Cluster: Epidermal growth factor receptor; n=1; ... 155 5e-36
UniRef50_O76385 Cluster: Putative uncharacterized protein; n=3; ... 155 5e-36
UniRef50_Q9XVQ7 Cluster: Putative uncharacterized protein; n=2; ... 155 6e-36
UniRef50_Q6VU50 Cluster: Eph receptor; n=3; Endopterygota|Rep: E... 155 6e-36
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 155 6e-36
UniRef50_Q4H3M7 Cluster: Ephrin receptor; n=3; Ciona|Rep: Ephrin... 155 8e-36
UniRef50_A7SE14 Cluster: Predicted protein; n=4; Nematostella ve... 155 8e-36
UniRef50_UPI0000ECD739 Cluster: Cytoplasmic tyrosine-protein kin... 154 1e-35
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 154 1e-35
UniRef50_Q5D184 Cluster: Ephrin receptor; n=2; Apocrita|Rep: Eph... 154 1e-35
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 154 1e-35
UniRef50_Q15375 Cluster: Ephrin type-A receptor 7 precursor; n=5... 154 1e-35
UniRef50_P00533 Cluster: Epidermal growth factor receptor precur... 154 1e-35
UniRef50_Q4SP88 Cluster: Ephrin receptor; n=2; Tetraodon nigrovi... 154 1e-35
UniRef50_P00534 Cluster: Tyrosine-protein kinase transforming pr... 154 1e-35
UniRef50_UPI000069DB6A Cluster: Ephrin type-A receptor 6 precurs... 153 2e-35
UniRef50_Q9Y1Y0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 153 2e-35
UniRef50_UPI00015B6067 Cluster: PREDICTED: similar to tyrosine p... 153 3e-35
UniRef50_Q4SMF1 Cluster: Chromosome 8 SCAF14552, whole genome sh... 153 3e-35
UniRef50_UPI0000E48069 Cluster: PREDICTED: hypothetical protein;... 153 3e-35
UniRef50_Q4T272 Cluster: Chromosome undetermined SCAF10323, whol... 153 3e-35
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 153 3e-35
UniRef50_UPI0000499A85 Cluster: protein kinase; n=1; Entamoeba h... 152 4e-35
UniRef50_Q9Y1Y8 Cluster: Protein tyrosine kinase; n=2; Metazoa|R... 152 6e-35
UniRef50_Q17C76 Cluster: Focal adhesion kinase; n=2; Culicidae|R... 152 6e-35
UniRef50_A7SAX2 Cluster: Predicted protein; n=3; Nematostella ve... 152 6e-35
UniRef50_Q4SWL0 Cluster: Ephrin receptor; n=3; Tetraodontidae|Re... 151 8e-35
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 151 8e-35
UniRef50_A7SI92 Cluster: Predicted protein; n=2; Nematostella ve... 151 8e-35
UniRef50_UPI0000E48358 Cluster: PREDICTED: hypothetical protein;... 151 1e-34
UniRef50_UPI000065F9C5 Cluster: Epithelial discoidin domain-cont... 151 1e-34
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 151 1e-34
UniRef50_Q4H3M4 Cluster: Ephrin receptor; n=2; Ciona intestinali... 151 1e-34
UniRef50_Q6SAW1 Cluster: Epidermal growth factor receptor; n=70;... 150 2e-34
UniRef50_Q6SAJ2 Cluster: Epidermal growth factor receptor; n=11;... 149 4e-34
UniRef50_P29322 Cluster: Ephrin type-A receptor 8 precursor; n=2... 149 4e-34
UniRef50_Q9U531 Cluster: Focal adhesion kinase homolog DFak56; n... 149 6e-34
UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Da... 148 7e-34
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 148 7e-34
UniRef50_O17391 Cluster: Protein kinase protein 9, isoform b; n=... 148 7e-34
UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 prote... 148 1e-33
UniRef50_Q8T0W6 Cluster: Putative insulin receptor precursor; n=... 148 1e-33
UniRef50_O45232 Cluster: Putative uncharacterized protein ark-1;... 148 1e-33
UniRef50_Q4RXA0 Cluster: Chromosome 11 SCAF14979, whole genome s... 147 1e-33
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 147 2e-33
UniRef50_Q7PT15 Cluster: ENSANGP00000009263; n=2; Culicidae|Rep:... 147 2e-33
UniRef50_Q22489 Cluster: Putative uncharacterized protein; n=4; ... 146 2e-33
UniRef50_Q7YZH5 Cluster: MBTK3; n=1; Monosiga brevicollis|Rep: M... 146 3e-33
UniRef50_Q10925-2 Cluster: Isoform b of Q10925 ; n=2; Caenorhabd... 146 4e-33
UniRef50_Q10925 Cluster: Probable tyrosine-protein kinase kin-25... 146 4e-33
UniRef50_UPI0000660568 Cluster: Ephrin type-B receptor 2 precurs... 145 5e-33
UniRef50_P29323 Cluster: Ephrin type-B receptor 2 precursor; n=3... 145 5e-33
UniRef50_Q4SR43 Cluster: Chromosome 11 SCAF14528, whole genome s... 145 7e-33
UniRef50_A7RX97 Cluster: Predicted protein; n=1; Nematostella ve... 145 7e-33
UniRef50_A2CG59 Cluster: Eph receptor B1; n=23; Euteleostomi|Rep... 144 9e-33
UniRef50_O17755 Cluster: Putative uncharacterized protein; n=3; ... 144 9e-33
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 144 9e-33
UniRef50_A0JMM7 Cluster: Zgc:154019; n=2; Danio rerio|Rep: Zgc:1... 144 1e-32
UniRef50_UPI0000E47C0F Cluster: PREDICTED: similar to focal adhe... 144 2e-32
UniRef50_UPI0000D576E5 Cluster: PREDICTED: similar to CG33531-PA... 144 2e-32
UniRef50_UPI000051AB92 Cluster: PREDICTED: similar to Fak-like t... 143 2e-32
UniRef50_UPI000065F647 Cluster: Ephrin type-B receptor 2 precurs... 143 3e-32
UniRef50_Q4SFJ9 Cluster: Chromosome 7 SCAF14601, whole genome sh... 143 3e-32
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 142 4e-32
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 142 4e-32
UniRef50_UPI00015B4221 Cluster: PREDICTED: similar to tyrosine-p... 142 5e-32
UniRef50_UPI0000D8BE91 Cluster: UPI0000D8BE91 related cluster; n... 142 5e-32
UniRef50_Q4SC90 Cluster: Chromosome undetermined SCAF14659, whol... 142 5e-32
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 142 5e-32
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 142 6e-32
UniRef50_P35916 Cluster: Vascular endothelial growth factor rece... 142 6e-32
UniRef50_P36888 Cluster: FL cytokine receptor precursor; n=33; A... 142 6e-32
UniRef50_Q4RV12 Cluster: Ephrin receptor; n=2; Tetraodontidae|Re... 141 8e-32
UniRef50_O01798 Cluster: Defective spermatogenesis protein 8; n=... 141 1e-31
UniRef50_O01325 Cluster: Putative uncharacterized protein; n=2; ... 141 1e-31
UniRef50_Q4H3M5 Cluster: Ephrin receptor; n=1; Ciona intestinali... 140 1e-31
UniRef50_Q27HR1 Cluster: Ret tyrosine-kinase receptor; n=1; Bran... 140 1e-31
UniRef50_Q25177 Cluster: Receptor protein-tyrosine kinase; n=2; ... 140 2e-31
UniRef50_Q4SUM3 Cluster: Ephrin receptor; n=4; Tetraodon nigrovi... 140 3e-31
UniRef50_Q61B52 Cluster: Putative uncharacterized protein CBG134... 140 3e-31
UniRef50_Q4H2M8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 140 3e-31
UniRef50_Q4RH14 Cluster: Chromosome undetermined SCAF15074, whol... 139 3e-31
UniRef50_Q4H3M3 Cluster: Ephrin receptor like protein; n=1; Cion... 139 3e-31
UniRef50_Q8AXB3 Cluster: Vascular endothelial growth factor rece... 139 3e-31
UniRef50_O61460 Cluster: Ephrin receptor 1 precursor; n=3; Caeno... 139 3e-31
UniRef50_UPI00015B629F Cluster: PREDICTED: similar to CG33531-PA... 139 4e-31
UniRef50_Q9U3B5 Cluster: Putative uncharacterized protein; n=3; ... 139 4e-31
UniRef50_Q18865 Cluster: Putative uncharacterized protein; n=5; ... 139 4e-31
UniRef50_P42159 Cluster: Class II receptor tyrosine kinase; n=5;... 139 4e-31
UniRef50_UPI00015B6341 Cluster: PREDICTED: similar to KLG; n=1; ... 138 6e-31
UniRef50_Q9TYX4 Cluster: Putative uncharacterized protein R11E3.... 138 6e-31
UniRef50_A7RGV3 Cluster: Predicted protein; n=1; Nematostella ve... 138 6e-31
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 138 6e-31
UniRef50_UPI0000DB7A04 Cluster: PREDICTED: similar to lemur tyro... 138 8e-31
UniRef50_Q4RP85 Cluster: Tyrosine-protein kinase receptor; n=3; ... 137 1e-30
UniRef50_A3EXK6 Cluster: Fibroblast growth factor receptor c; n=... 137 1e-30
UniRef50_P34925 Cluster: Tyrosine-protein kinase RYK precursor; ... 137 1e-30
UniRef50_Q4L0H7 Cluster: Insulin receptor tyrosine kinase; n=2; ... 137 2e-30
UniRef50_P34265 Cluster: Probable tyrosine-protein kinase kin-31... 137 2e-30
UniRef50_Q9Y1Y4 Cluster: Tyrosine-protein kinase; n=1; Ephydatia... 136 2e-30
UniRef50_A7RL50 Cluster: Predicted protein; n=1; Nematostella ve... 136 2e-30
UniRef50_Q9Y1X7 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 136 3e-30
UniRef50_UPI0000E470E3 Cluster: PREDICTED: similar to Fer, parti... 136 4e-30
UniRef50_UPI0000DB7B4C Cluster: PREDICTED: similar to hopscotch ... 135 6e-30
UniRef50_P35968 Cluster: Vascular endothelial growth factor rece... 135 6e-30
UniRef50_Q96Q04 Cluster: Serine/threonine-protein kinase LMTK3 p... 135 6e-30
UniRef50_UPI0000D563AD Cluster: PREDICTED: similar to CG3969-PA,... 135 7e-30
UniRef50_Q4SJQ3 Cluster: Tyrosine-protein kinase receptor; n=1; ... 135 7e-30
UniRef50_Q4JDD5 Cluster: Tyrosine-protein kinase receptor; n=5; ... 135 7e-30
UniRef50_Q25198 Cluster: Receptor tyrosine kinase 90; n=1; Hydra... 135 7e-30
UniRef50_Q5GIT4 Cluster: Vascular endothelial growth factor rece... 135 7e-30
UniRef50_UPI0000D56AE3 Cluster: PREDICTED: similar to CG1594-PA;... 134 1e-29
UniRef50_Q1HTP1 Cluster: Tyrosine-protein kinase receptor; n=1; ... 134 1e-29
UniRef50_Q9XYS4 Cluster: Tyrosine kinase receptor HTK32; n=1; Hy... 134 1e-29
UniRef50_Q4H3N3 Cluster: Epidermal growth factor receptor; n=1; ... 134 1e-29
UniRef50_Q0MQ66 Cluster: Putative uncharacterized protein; n=5; ... 134 2e-29
UniRef50_Q9U8U8 Cluster: VEGFR-like; n=1; Branchiostoma belcheri... 133 2e-29
UniRef50_UPI0000D57516 Cluster: PREDICTED: similar to lemur tyro... 133 3e-29
UniRef50_Q6SAA3 Cluster: Epidermal growth factor receptor; n=39;... 133 3e-29
UniRef50_P07333 Cluster: Macrophage colony-stimulating factor 1 ... 133 3e-29
UniRef50_UPI0000DB7330 Cluster: PREDICTED: similar to Ack CG1499... 132 4e-29
UniRef50_P16234 Cluster: Alpha-type platelet-derived growth fact... 132 4e-29
UniRef50_Q8JFR5 Cluster: Mast/stem cell growth factor receptor p... 132 5e-29
UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA;... 132 7e-29
UniRef50_Q4RXB0 Cluster: Chromosome 11 SCAF14979, whole genome s... 132 7e-29
UniRef50_UPI00015B6363 Cluster: PREDICTED: similar to tyrosine p... 131 9e-29
UniRef50_A7RNB2 Cluster: Predicted protein; n=1; Nematostella ve... 131 9e-29
UniRef50_P17948 Cluster: Vascular endothelial growth factor rece... 131 9e-29
UniRef50_UPI00006A1E7A Cluster: Non-receptor tyrosine-protein ki... 131 1e-28
UniRef50_UPI0000F306DC Cluster: Serine/threonine-protein kinase ... 131 1e-28
UniRef50_P21860 Cluster: Receptor tyrosine-protein kinase erbB-3... 131 1e-28
UniRef50_A7SP77 Cluster: Predicted protein; n=1; Nematostella ve... 130 2e-28
UniRef50_Q640T5 Cluster: Tyrosine-protein kinase receptor; n=2; ... 130 2e-28
UniRef50_Q6SAX5 Cluster: Epidermal growth factor receptor; n=14;... 130 2e-28
UniRef50_Q13470 Cluster: Non-receptor tyrosine-protein kinase TN... 130 2e-28
UniRef50_P42687 Cluster: Tyrosine-protein kinase SPK-1; n=1; Gir... 130 2e-28
UniRef50_P24348 Cluster: Receptor tyrosine-protein kinase let-23... 130 3e-28
UniRef50_Q07912 Cluster: Activated CDC42 kinase 1; n=24; Euteleo... 130 3e-28
UniRef50_Q6ZMQ8-3 Cluster: Isoform 3 of Q6ZMQ8 ; n=6; Tetrapoda|... 129 4e-28
UniRef50_Q9VLQ8 Cluster: CG8222-PA, isoform A; n=8; Sophophora|R... 129 4e-28
UniRef50_Q8T4M0 Cluster: VEGFR-A splice form A; n=4; Diptera|Rep... 129 4e-28
UniRef50_Q6ZMQ8 Cluster: Serine/threonine-protein kinase LMTK1; ... 129 4e-28
UniRef50_UPI0000519EF1 Cluster: PREDICTED: similar to CG31640-PA... 129 5e-28
UniRef50_Q179Z3 Cluster: Tyrosine-protein kinase; n=1; Aedes aeg... 129 5e-28
UniRef50_Q9XW34 Cluster: Putative uncharacterized protein; n=3; ... 128 6e-28
UniRef50_Q9GZG1 Cluster: Putative uncharacterized protein; n=6; ... 128 6e-28
UniRef50_Q23102 Cluster: Putative uncharacterized protein; n=1; ... 128 6e-28
UniRef50_Q17833 Cluster: Putative uncharacterized protein old-1;... 128 8e-28
UniRef50_UPI0000E4A99A Cluster: PREDICTED: similar to tyrosine k... 128 1e-27
UniRef50_UPI0000E49426 Cluster: PREDICTED: hypothetical protein;... 128 1e-27
UniRef50_UPI000065E2FA Cluster: Homolog of Homo sapiens "Tyrosin... 128 1e-27
UniRef50_P91360 Cluster: Putative uncharacterized protein; n=1; ... 128 1e-27
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 128 1e-27
UniRef50_Q8ITG6 Cluster: Focal adhesion kinase; n=2; Protostomia... 127 1e-27
UniRef50_P10721 Cluster: Mast/stem cell growth factor receptor p... 127 1e-27
UniRef50_O02742 Cluster: Activated CDC42 kinase 2; n=13; Euteleo... 127 1e-27
UniRef50_P79884 Cluster: Insulin-like growth factor-I receptor; ... 127 2e-27
UniRef50_UPI0000DB74F2 Cluster: PREDICTED: similar to Derailed 2... 126 3e-27
UniRef50_Q4SF69 Cluster: Chromosome undetermined SCAF14608, whol... 126 3e-27
UniRef50_Q59FL9 Cluster: Fibroblast growth factor receptor 3 iso... 126 3e-27
UniRef50_UPI000065FEDC Cluster: Activated CDC42 kinase 1 (EC 2.7... 126 3e-27
UniRef50_Q5G254 Cluster: Erbb3; n=6; Danio rerio|Rep: Erbb3 - Da... 126 3e-27
UniRef50_Q0IFX6 Cluster: Pdgf/vegf receptor; n=1; Aedes aegypti|... 126 3e-27
UniRef50_P79749 Cluster: Beta-type platelet-derived growth facto... 126 3e-27
UniRef50_UPI000049A16F Cluster: protein kinase; n=1; Entamoeba h... 126 4e-27
UniRef50_UPI000069F079 Cluster: Serine/threonine-protein kinase ... 126 4e-27
UniRef50_A4IIX3 Cluster: Putative uncharacterized protein; n=1; ... 126 4e-27
UniRef50_Q16LR4 Cluster: Tyrosine protein kinase; n=5; Coelomata... 126 4e-27
UniRef50_Q24592 Cluster: Tyrosine-protein kinase hopscotch; n=2;... 126 4e-27
UniRef50_Q8UVR8 Cluster: Macrophage colony-stimulating factor 1 ... 126 4e-27
UniRef50_UPI00015B4DC3 Cluster: PREDICTED: similar to receptor t... 125 6e-27
UniRef50_UPI000065DACB Cluster: Homolog of Homo sapiens "Splice ... 125 6e-27
UniRef50_Q9VZI2 Cluster: CG14992-PA; n=3; Sophophora|Rep: CG1499... 125 6e-27
UniRef50_Q17HL3 Cluster: Discoidin domain receptor; n=3; Culicid... 125 6e-27
UniRef50_Q61CN6 Cluster: Putative uncharacterized protein CBG128... 125 8e-27
UniRef50_UPI00004CFD13 Cluster: Serine/threonine-protein kinase ... 124 1e-26
UniRef50_Q86MD7 Cluster: EGF receptor; n=1; Echinococcus multilo... 124 1e-26
UniRef50_Q20933 Cluster: Putative uncharacterized protein; n=1; ... 124 1e-26
UniRef50_Q4H3A3 Cluster: Janus kinase; n=1; Ciona intestinalis|R... 124 1e-26
UniRef50_O60674 Cluster: Tyrosine-protein kinase JAK2; n=48; Eut... 124 2e-26
UniRef50_Q4RR57 Cluster: Chromosome 14 SCAF15003, whole genome s... 123 2e-26
UniRef50_Q24327 Cluster: Gp160-Dtrk precursor; n=4; Sophophora|R... 123 2e-26
UniRef50_Q9I8N6 Cluster: Macrophage colony-stimulating factor 1 ... 123 2e-26
UniRef50_UPI0000EB1EAB Cluster: Serine/threonine-protein kinase ... 122 4e-26
UniRef50_Q16UV1 Cluster: Protein kinase protein; n=3; Culicidae|... 122 4e-26
UniRef50_O02064 Cluster: Putative uncharacterized protein; n=1; ... 122 4e-26
UniRef50_P09619 Cluster: Beta-type platelet-derived growth facto... 122 4e-26
UniRef50_UPI00015B5A01 Cluster: PREDICTED: similar to protein ki... 122 5e-26
UniRef50_UPI0000DB7A0A Cluster: PREDICTED: similar to FMS-like t... 122 5e-26
UniRef50_Q03351 Cluster: NT-3 growth factor receptor precursor; ... 122 5e-26
UniRef50_UPI0000F1D883 Cluster: PREDICTED: hypothetical protein;... 122 7e-26
UniRef50_Q6W5B1 Cluster: TEL/JAK2 fusion protein; n=4; Danio rer... 122 7e-26
UniRef50_UPI0000D56EE8 Cluster: PREDICTED: similar to CG14992-PA... 121 1e-25
UniRef50_Q5BXN9 Cluster: SJCHGC05493 protein; n=1; Schistosoma j... 121 1e-25
UniRef50_Q21041 Cluster: Putative uncharacterized protein ver-4;... 121 1e-25
UniRef50_Q8QGM7 Cluster: C-ros-like receptor; n=3; Danio rerio|R... 120 2e-25
UniRef50_UPI00006A26D5 Cluster: UPI00006A26D5 related cluster; n... 120 3e-25
UniRef50_Q19238 Cluster: Putative tyrosine-protein kinase F09A5.... 120 3e-25
UniRef50_Q8IWU2 Cluster: Serine/threonine-protein kinase LMTK2 p... 120 3e-25
UniRef50_UPI0000DB7238 Cluster: PREDICTED: similar to Discoidin ... 119 4e-25
UniRef50_UPI000065D1E0 Cluster: BDNF/NT-3 growth factors recepto... 119 5e-25
UniRef50_P18475 Cluster: Tyrosine-protein kinase receptor torso ... 119 5e-25
UniRef50_UPI00015B5C00 Cluster: PREDICTED: similar to VEGFR-A sp... 118 7e-25
UniRef50_UPI0000F1F8B4 Cluster: PREDICTED: hypothetical protein;... 118 7e-25
UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164... 118 7e-25
UniRef50_Q27324 Cluster: Tyrosine-protein kinase Drl precursor; ... 118 7e-25
UniRef50_P52333 Cluster: Tyrosine-protein kinase JAK3; n=17; Eut... 118 7e-25
UniRef50_P23458 Cluster: Tyrosine-protein kinase JAK1; n=55; Eut... 118 1e-24
UniRef50_O12990 Cluster: Tyrosine-protein kinase Jak1; n=8; Eute... 118 1e-24
UniRef50_Q22765 Cluster: Putative uncharacterized protein; n=3; ... 117 2e-24
UniRef50_UPI00015B54DC Cluster: PREDICTED: similar to vascular e... 117 2e-24
UniRef50_Q9I9L1 Cluster: Arg protein-tyrosine kinase; n=12; Tetr... 117 2e-24
UniRef50_Q5DM52 Cluster: Receptor tyrosine kinase Torso-like pro... 117 2e-24
UniRef50_UPI00005A2D48 Cluster: PREDICTED: similar to EPH recept... 116 3e-24
UniRef50_Q4S6E0 Cluster: Chromosome 10 SCAF14728, whole genome s... 116 3e-24
UniRef50_Q25199 Cluster: Tyrosine kinase receptor; n=7; Hydra|Re... 116 3e-24
UniRef50_UPI0001556099 Cluster: PREDICTED: similar to PTK7 prote... 116 4e-24
UniRef50_UPI00006A0A62 Cluster: High affinity nerve growth facto... 116 4e-24
UniRef50_UPI000065D8B4 Cluster: Basic fibroblast growth factor r... 116 4e-24
UniRef50_Q1HTP2 Cluster: Tyrosine-protein kinase receptor; n=4; ... 116 4e-24
UniRef50_Q6J4P8 Cluster: Insulin-like receptor; n=2; Apis mellif... 116 4e-24
UniRef50_Q59DZ7 Cluster: CG33531-PA; n=6; Sophophora|Rep: CG3353... 116 4e-24
UniRef50_Q16VL6 Cluster: Tyrosine-protein kinase; n=1; Aedes aeg... 116 4e-24
UniRef50_Q4RHE1 Cluster: Chromosome 3 SCAF15050, whole genome sh... 116 5e-24
UniRef50_Q26566 Cluster: Epidermal growth factor receptor precur... 116 5e-24
UniRef50_O76809 Cluster: Receptor tyrosine kinase HTK30; n=1; Hy... 115 6e-24
UniRef50_Q5JZY3 Cluster: Ephrin type-A receptor 10 precursor; n=... 115 6e-24
UniRef50_Q3TYD6 Cluster: Serine/threonine-protein kinase LMTK2 p... 114 1e-23
UniRef50_O15197 Cluster: Ephrin type-B receptor 6 precursor; n=2... 114 1e-23
UniRef50_Q9U8U9 Cluster: PDGFR-like; n=1; Eptatretus burgeri|Rep... 114 1e-23
UniRef50_Q9PWD1 Cluster: Tyrosine-protein kinase; n=3; Tetraodon... 114 1e-23
UniRef50_Q4S8H3 Cluster: Chromosome 2 SCAF14705, whole genome sh... 114 1e-23
UniRef50_Q4S883 Cluster: Chromosome 3 SCAF14707, whole genome sh... 114 1e-23
UniRef50_Q8T0Z7 Cluster: Tyrosine kinase-like protein; n=1; Bomb... 113 2e-23
UniRef50_O17408 Cluster: Putative uncharacterized protein; n=1; ... 113 3e-23
UniRef50_Q9TX48 Cluster: 220 kDa ABL-related protein tyrosine ki... 112 4e-23
UniRef50_UPI0000F1DBB6 Cluster: PREDICTED: hypothetical protein;... 112 6e-23
UniRef50_Q9M085 Cluster: Protein kinase-like protein; n=22; Magn... 112 6e-23
UniRef50_Q61BE3 Cluster: Putative uncharacterized protein CBG133... 112 6e-23
UniRef50_UPI00015B46B5 Cluster: PREDICTED: similar to CG33531-PA... 111 8e-23
UniRef50_Q4RU24 Cluster: Chromosome 12 SCAF14996, whole genome s... 111 8e-23
UniRef50_Q60WJ5 Cluster: Putative uncharacterized protein CBG191... 111 8e-23
UniRef50_Q17PG3 Cluster: Tyrosine-protein kinase drl; n=5; Endop... 111 1e-22
UniRef50_Q5TCX8 Cluster: Mitogen-activated protein kinase kinase... 111 1e-22
UniRef50_P34892 Cluster: Receptor-like tyrosine-protein kinase k... 111 1e-22
UniRef50_Q9XZ66 Cluster: Tyrosine kinase receptor-related protei... 111 1e-22
UniRef50_Q70W05 Cluster: Src protein; n=1; Ciona intestinalis|Re... 111 1e-22
UniRef50_P34891 Cluster: Receptor-like tyrosine-protein kinase k... 111 1e-22
UniRef50_UPI00015B55E2 Cluster: PREDICTED: similar to tyrosine-p... 110 2e-22
UniRef50_UPI000065E468 Cluster: Homolog of Gallus gallus "Ephrin... 110 2e-22
UniRef50_Q4T1R9 Cluster: Chromosome 4 SCAF10492, whole genome sh... 110 2e-22
UniRef50_Q21038 Cluster: Putative uncharacterized protein ver-3;... 110 2e-22
UniRef50_UPI00015B629D Cluster: PREDICTED: similar to CG33531-PA... 109 3e-22
UniRef50_Q5TRF2 Cluster: ENSANGP00000025511; n=1; Anopheles gamb... 109 3e-22
UniRef50_Q6GPK5 Cluster: Tyrosine-protein kinase; n=4; Euteleost... 109 4e-22
UniRef50_UPI0000D576E4 Cluster: PREDICTED: similar to CG33531-PA... 109 5e-22
>UniRef50_UPI0000D57520 Cluster: PREDICTED: similar to CG8250-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG8250-PA
- Tribolium castaneum
Length = 1284
Score = 917 bits (2269), Expect = 0.0
Identities = 485/1112 (43%), Positives = 638/1112 (57%), Gaps = 78/1112 (7%)
Query: 2 ENMVVKSPPFRGLWEFCKFEALLHQRMMQNASIRLISESTISE-------VQWILQEVAG 54
E + V SP F C+ + ++Q M NA IR++ + T + QW+++ + G
Sbjct: 4 EFLHVTSPLFSPTRNSCRLQVWIYQENMNNAEIRIVGDKTTNHSQSINNHTQWLVERIRG 63
Query: 55 NNAENWYPMRFMIGKVQQEVRIIIEITRPNYVSLAQPLPHIAIDNIRMIDCVPEPPVYNG 114
+N++ W IGK+ + II+E+ ++ +A DNI + C P+ +
Sbjct: 64 DNSKKWRKYESPIGKMSENFTIILEVVPSQTITQGAV---VAFDNIALTHCYPK---LDD 117
Query: 115 ECNAGQLKCKIMNRESCIKLHQVCDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGFVD 174
C Q +CK + +CI +CD+ +DC G DE++NCD MPYGS C FE+D CG+ +
Sbjct: 118 TCTPHQYRCK--STTNCINNTSICDITQDCLLGDDERQNCDGMPYGSRCTFEEDWCGWYN 175
Query: 175 VPQPILKWSRHRGPTPTDKTGPNYDHTCGPPTQPNLNPTKKVPPLTPPFHMHCAGYYFFV 234
V IL+W+RH G TPT+ TGPNYDHT + + G Y FV
Sbjct: 176 VEGRILEWTRHNGSTPTNYTGPNYDHT----------------------YKNSTGKYLFV 213
Query: 235 NMNVTGPNKEKADFASTAVMKTVIFNPPPKVHGDVASKYYNCCMVRFYYQQNGRNYGSLS 294
NM KE+A FAS+A +++VIFNPPP+VHG+V+SKYYN C +RFY Q G++ +
Sbjct: 214 NML-----KEEASFASSATLRSVIFNPPPRVHGNVSSKYYNSCAIRFYLHQTGKHKSGIQ 268
Query: 295 VDVVELTARGNISTSVWFSTKDKGENWYRASIFLPNVTRRYYLQFKTRMGMRIYSDSAID 354
+ V EL N ST + +S D G+ W R LPN+T +Y++ F + G R SD AID
Sbjct: 269 LQVTELKPTDNYSTEILWSFIDYGDKWIRQVFILPNITHKYFIHFDAKRGYRYISDIAID 328
Query: 355 DFSMSPECFGLNVDPEELGDYNYYDPVFDEKT---TPHKDFTGRVYYRFTPCGASGRYGP 411
D S+SPECFGLN+ PEEL YNY++P +DE HK F Y T C A GR+GP
Sbjct: 329 DVSLSPECFGLNIPPEELNGYNYWNP-YDEHVGGRETHKHFVNETSYHITTCNAKGRFGP 387
Query: 412 NQTMCDAAYNNTPVDVNVLHTHPYTGVQVWEVPEEGLYTIIATXXXXXXXXXXXXXXHGA 471
+ C AYN+T V V VL +GVQ W P +G YT I GA
Sbjct: 388 TERNCAVAYNHTKVKVKVLSEPGLSGVQKWTSPSDGFYTFILVGASGGKGSGAMGSSRGA 447
Query: 472 QARALLELHRSELVYMLIGQQGINACKKTLSAQESQECSRKPSNESLQVFTSKTHEVRNT 531
R +LEL + + +YMLIGQ+G +AC K+L + + CS +++ ++ E N
Sbjct: 448 MVRVVLELRKGQEIYMLIGQEGTSACVKSLGHEGNSSCSSVKNDDRVKGI----REFLNM 503
Query: 532 HVIDXXXXXXXXTFVFLMDKEGRPFPLVVAXXXXXISVGIFRDDGSQHGKPHTNSTPE-S 590
+ D TF+FL +K + P+ VA + +G F D G QHG+ S P +
Sbjct: 504 TINDGGGGGGGATFLFLRNKSRQYIPIAVAAGGGGLGLGRFIDTGRQHGQAINMSKPPFT 563
Query: 591 GYMYGQPDKTSEYVVLGTGAGGGWVARSGPITPGSERVRGAALREXXXXXXXXXXXXXXX 650
G MYG K S GAGGGW G + G +++ G AL +
Sbjct: 564 GRMYG---KNS------AGAGGGWKMFPGIVNVGHKQLMGRALLDGGGIGGRACYNSTDD 614
Query: 651 XXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXWSYIDGSRALRVYSDVSVAPRT 703
+SYID SR + S+
Sbjct: 615 RGYGGFGGGGGGCRSGGGGGGFAGGDATSTNTTNGEGGYSYIDPSRTVLNLSEAHSGYNA 674
Query: 704 GPGEVLIIPAIHDCGCDYRCVALNEFRSEVRCYCPSSWVFNPMDPGKCVYPNTWFTVEGE 763
GPG VLIIPAI C C+YRCVAL+ +S C CP +W + D C+ G+
Sbjct: 675 GPGSVLIIPAIPGCDCNYRCVALDSRKSLTACICPKNWKLDS-DGKTCITVPE--NAAGD 731
Query: 764 WSTFTWTIVASSIGCXXXXXXXXXXXXXYNRYQKKREARQAQKRIMEQEVQLHRLRNAPG 823
+++ ++ S+ YNRYQ + +K + ++QL RLR A
Sbjct: 732 ATSWILIVLIISV-IFLTTLVAFICFILYNRYQHQASGILRRKMLSGADLQLDRLRVA-- 788
Query: 824 GNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRS 883
+++ +NP+Y + D++ +P RE L+LVKALGQGAFGEVYQG YR R
Sbjct: 789 --SDSMMTEYNPNYEFGGVVYTLKDLKDIP---REQLRLVKALGQGAFGEVYQGFYRQRP 843
Query: 884 ADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELL 943
D EMPVAVKTLPE+ST QAE DFLMEA IM+KFNH NIVH IGVCFD+HPRFIVLELL
Sbjct: 844 CDTVEMPVAVKTLPEMSTSQAEMDFLMEALIMSKFNHPNIVHFIGVCFDKHPRFIVLELL 903
Query: 944 AGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTS 1003
AGGDLKNFLRESRPKPER S LTMKDL+L +VDV KGC+YLE RFIHRDIAARNCLLT+
Sbjct: 904 AGGDLKNFLRESRPKPERGSPLTMKDLVLIAVDVAKGCKYLEDNRFIHRDIAARNCLLTT 963
Query: 1004 RGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLL 1063
+GPGRVVKIADFGM+RD+YR+DYY+KGGKAMLPIKWMPPEA++DG+FT+KTDVWSFGVLL
Sbjct: 964 KGPGRVVKIADFGMSRDVYRSDYYRKGGKAMLPIKWMPPEAFLDGIFTSKTDVWSFGVLL 1023
Query: 1064 WEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
WE+ S+G MPYTGCANREVM+LV+ GGRL+ P
Sbjct: 1024 WEIMSMGYMPYTGCANREVMQLVTSGGRLDPP 1055
>UniRef50_Q7KJ08 Cluster: Receptor protein tyrosine kinase ALK splice
variant A; n=9; Diptera|Rep: Receptor protein tyrosine
kinase ALK splice variant A - Drosophila melanogaster
(Fruit fly)
Length = 1701
Score = 517 bits (1275), Expect = e-145
Identities = 251/414 (60%), Positives = 301/414 (72%), Gaps = 9/414 (2%)
Query: 683 SYIDGSRALRVYSDVSVAPRTGPGEVLIIPAIHDCGCDYRCVALNEFRSEVRCYCPSSWV 742
SYI SR+LR S++ +GPG ++IIPAI CGCDYRCVAL+EFRS+VRC CP W
Sbjct: 1023 SYISPSRSLREISEIHAGASSGPGAIIIIPAIEGCGCDYRCVALDEFRSKVRCICPDGWS 1082
Query: 743 FNPMDPGKCVYPNTWFTVEGEWSTFTWTIVASSIGCXXXXX-XXXXXXXXYNRYQKKREA 801
+ C E S+F + + I YNRYQ+K+++
Sbjct: 1083 LKRDNHTACEIRE-----EAGKSSFQYLVSILMISLAVLFICIAALIFMLYNRYQRKKQS 1137
Query: 802 RQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLK 861
++ K ++EQ++QL RLRN D++ FNP+YG + L IDV LPQV+R+SL+
Sbjct: 1138 KKRHKMLVEQDLQLTRLRN---NIDDSNLNNFNPNYGCDGILNGHIDVNSLPQVARDSLQ 1194
Query: 862 LVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHA 921
LV ALG+GAFGEVY LYRHR DA EM VAVKTL E + E DFL EAAIMAKFNH
Sbjct: 1195 LVNALGKGAFGEVYMALYRHRDGDAVEMGVAVKTLREDPKREKEEDFLKEAAIMAKFNHP 1254
Query: 922 NIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGC 981
N+VHLIGVCFDR P +IVLELLAGGDL+ FLRE+R PER S LTMKDLL C++DV KGC
Sbjct: 1255 NMVHLIGVCFDRQPYYIVLELLAGGDLQKFLRENRNTPERPSLLTMKDLLFCALDVAKGC 1314
Query: 982 RYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMP 1041
RY+E+KRFIHRDIAARNCLL+S+GPGRVVKIADFGM+RDIYR+DYY+KGGKAMLPIKWMP
Sbjct: 1315 RYMESKRFIHRDIAARNCLLSSKGPGRVVKIADFGMSRDIYRSDYYRKGGKAMLPIKWMP 1374
Query: 1042 PEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
PEA++DG+FT+KTDVWSFG+LLWEVFSLG PY G N +VMELV GGRL P
Sbjct: 1375 PEAFLDGIFTSKTDVWSFGILLWEVFSLGRSPYPGQHNTQVMELVVRGGRLGSP 1428
Score = 458 bits (1128), Expect = e-127
Identities = 247/623 (39%), Positives = 353/623 (56%), Gaps = 40/623 (6%)
Query: 8 SPPFRGLWEFCKFEALLHQRMMQNASIRLISEST-ISEVQWILQEVAGNNAENWYPMRFM 66
SP F E C E +HQ M + R++ E +E W+ E+ G+N W +
Sbjct: 353 SPEFSTTMEKCFLEVYMHQSDMSHGLSRVVVELLHTAESSWVPAEILGDNVRQWTRKVYR 412
Query: 67 IGKVQQEVRIIIEITRPNYVSLAQPLPHIAIDNIRMIDCVPEPPVYNGECNAGQLKCKIM 126
+G+V ++ RI+ E+ P+ + + Q H+A+DN+RM++C PE + +C+ Q+KC
Sbjct: 413 LGRVSRDFRIVFEVV-PD-LRVGQK-GHVALDNLRMVNCFPEG-TKSEKCSTSQVKCTSS 468
Query: 127 NRESCIKLHQVCDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGFVDVPQPILKWSRHR 186
CI L ++CD+ +DCD+ DEQ++CDK+PYG C+FE+D CG+ D + L WSRH
Sbjct: 469 KVPVCIHLPRICDITRDCDEAEDEQQSCDKIPYGGRCDFEEDWCGWRDSGKTTLTWSRHT 528
Query: 187 GPTPTDKTGPNYDHTCGPPTQPNLNPTKKVPPLTPPFHMHCAGYYFFVNMNVTGPNKEKA 246
G +PT TGP+ DHT Q N T +GYY VNMN N EK
Sbjct: 529 GSSPTHDTGPDGDHTM----QHLQNNT--------------SGYYMLVNMNQHMNNSEKN 570
Query: 247 D---FASTAVMKTVIFNPPPKVHGDVASKYYNCCMVRFYYQQNGRNYGSLSVDVVELTAR 303
FAS A+M + FNPPP VHG+ S Y N C+VRF+ Q G+N GS+++ VVE+ +
Sbjct: 571 SIIGFASNAIMVSKTFNPPPSVHGNPDSPYRNSCVVRFFIHQFGKNPGSINLSVVEMKEK 630
Query: 304 GNISTSVWFSTKDKGENWYRASIFLPNVTRRYYLQFKTRMGMRIYSDSAIDDFSMSPECF 363
NI+T++W+STK++G +W RA LPN+T +YYLQF+ RMGMRIYSD A+DDFS+SPECF
Sbjct: 631 ENITTTLWWSTKNQGSDWMRAEYVLPNITSKYYLQFEARMGMRIYSDVAVDDFSLSPECF 690
Query: 364 GLNVDPEELGDYNYYDPVFDEKTTPHKDFTGRVYYRFTPCGASGRYGPNQTMCDAAY--- 420
GLN+ + LG YNY+D + K+ +KDF Y T C G GP+Q C+AAY
Sbjct: 691 GLNIPEDHLGGYNYWDVRQNLKSPTYKDFEYTNYLELTTCDTRGMIGPSQAQCEAAYREQ 750
Query: 421 NNTPV--DVNVLHTH-PYTGVQVWEVPEEGLYTIIATXXXXXXXXXXXXXXHGAQARALL 477
N T V +V+V+ Y G+Q W+VP EG YTIIA G+ A A+L
Sbjct: 751 NKTHVLREVHVVEDQSSYKGMQKWKVPHEGHYTIIAKGASGGLGSGGVGSSRGSVAVAIL 810
Query: 478 ELHRSELVYMLIGQQGINACKKTLSAQESQECSRKPSNESLQV-FTSKTHEVRNTHVIDX 536
ELH++E +Y L+GQQG NAC K++ + C + Q F SK V+N ++ +
Sbjct: 811 ELHKNEELYFLVGQQGENACIKSMGVLKEAGCGTDHDLDLAQYSFRSKQDMVKNIYIENG 870
Query: 537 XXXXXXXTFVFLMDK-EGRPFPLVVAXXXXXISVGIFRDDGSQHG-KPHTNSTPESGYMY 594
++VFL+++ + PL+VA + +G + D+ QHG K PESG +
Sbjct: 871 AGGGGGGSYVFLLNQAKNEAVPLLVAGGGGGLGIGQYIDEDFQHGQKAKPLQAPESGQIN 930
Query: 595 GQPDKTSEYVVLGTGAGGGWVAR 617
G+P G GGGW A+
Sbjct: 931 GEPLNKKT-----AGPGGGWRAK 948
>UniRef50_UPI00015B5971 Cluster: PREDICTED: similar to leukocyte
receptor tyrosine protein kinase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to leukocyte receptor
tyrosine protein kinase - Nasonia vitripennis
Length = 1472
Score = 465 bits (1147), Expect = e-129
Identities = 222/394 (56%), Positives = 279/394 (70%), Gaps = 16/394 (4%)
Query: 704 GPGEVLIIPAIHDCGCDYRCVALNEFRSEVRCYCPSSWVFNPMDPGKCVYPNTWFTVEGE 763
GPGEVLIIPAI CGCD+RCV ++ SE C CP+ W D CV +
Sbjct: 778 GPGEVLIIPAISGCGCDFRCVVVDRHLSETHCLCPAGWQLGN-DSKACVMSEP----DPR 832
Query: 764 WSTFTWTIVASSIGCXXXXXXXXXXXXXYNRYQKKREARQAQKRIMEQEVQLHRLRNAPG 823
T ++ SIG YNRYQ ++E + ++ + +L LR
Sbjct: 833 HQTVMVVLIIVSIGLIIAFSGLCFLL--YNRYQNRKELERRRQVMFGNGTELTSLRVV-- 888
Query: 824 GNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRS 883
+++ FNP+Y F + LPQ+ R+S+ LVK LGQGAFGEV+QG+Y++
Sbjct: 889 --SDSMMTEFNPNY---EFAGNLYSFKDLPQIPRDSVTLVKPLGQGAFGEVFQGVYKYSR 943
Query: 884 ADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELL 943
++ E PVAVKTLP +ST QAE+DF+MEA IM+KF H NIV IG+ FD+HPR+IVLELL
Sbjct: 944 SE--EHPVAVKTLPSVSTSQAEADFMMEALIMSKFEHPNIVQFIGISFDKHPRYIVLELL 1001
Query: 944 AGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTS 1003
AGGDLKNFLRE RP+P+R + LTM+ L++C+ DV KGC+Y+E RFIHRDIAARNCLL+
Sbjct: 1002 AGGDLKNFLREERPRPDRPTTLTMQSLIMCAYDVAKGCKYMEEARFIHRDIAARNCLLSC 1061
Query: 1004 RGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLL 1063
+GPGRVVKIADFGMARDIYR+DYY+KGGKAMLPIKWMPPE+++DG+FTTKTDVW+FGVLL
Sbjct: 1062 KGPGRVVKIADFGMARDIYRSDYYRKGGKAMLPIKWMPPESFLDGIFTTKTDVWAFGVLL 1121
Query: 1064 WEVFSLGVMPYTGCANREVMELVSGGGRLEKPYG 1097
WE+ S G MPYTGCANREVM +V+ GGRLE+P G
Sbjct: 1122 WEIMSFGYMPYTGCANREVMSMVTSGGRLERPAG 1155
Score = 299 bits (734), Expect = 3e-79
Identities = 195/615 (31%), Positives = 284/615 (46%), Gaps = 62/615 (10%)
Query: 18 CKFEALLHQRMMQNASIRLISESTISEVQWILQEVAGNNAENWYPMRFMIGKVQQEVRII 77
C E L+Q M+ +I L+ E T ++ ++ +GN+ W +F +G + QE II
Sbjct: 124 CYLEVALYQVAMKRGTINLVIE-TFNKTSYLASMRSGNDNATWERSKFHLGSLNQEFSII 182
Query: 78 IEITRPNYVSLAQPLPHIAIDNIRMIDCVPEPPVYNGECNAGQLKCKIMNRESCIKLHQV 137
+E+ P S IA+D+I +++C PE Y EC +C N SC+K V
Sbjct: 183 LEMQAPFDNS------SIAVDDIDLVNCFPESRSY--ECTESMFRC---NNGSCLKREHV 231
Query: 138 CDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGFVDVPQPILKWSRHRGPTPTDKTGPN 197
CDL DC DG DE +CDK+P + CNFE CG+ +V L W+ H+GP P++
Sbjct: 232 CDLTADCADGEDETGDCDKVPEHAKCNFEGGWCGWSNVRGRPLNWTLHQGPMPSE----- 286
Query: 198 YDHTCGPPTQPNLNPTKKVPPLTPPFHMHCAGYYFFVNMNVTGPNKEKADFASTAVMKTV 257
++ P+ + + G Y +V+M+ K S A + +
Sbjct: 287 -----------------RMGPVADHTYRNGTGTYAYVDMS-----KTDLQLGSRATINSP 324
Query: 258 IFNPPPKVHGDVASKYYNCCMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFSTKDK 317
IFNP P + S Y N C VRF+Y Q G + L + +V+L + N S +W KD
Sbjct: 325 IFNPTPPYNHQPGSPYKNSCKVRFFYHQYGSHTVPLGLYLVQLKPQQNYSQQIWRYVKDN 384
Query: 318 GENWYRASIFLPNVTRRYYLQFKTRMGMRIYSDSAIDDFSMSPECFGLNVDPEELGDYNY 377
++W + LP+V RYYLQF+ + AIDD S+SPECFG+ V + L D+NY
Sbjct: 385 SDSWNSQLVTLPDVRYRYYLQFEASKSYASKAVVAIDDISLSPECFGVGVPADILADFNY 444
Query: 378 YD-PVFDEKTTP--HKDFTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPVDVNVLH--- 431
YD + E + P H DFT + R + CG +GR GP C N + V VL
Sbjct: 445 YDQKIPPEGSVPPKHADFTNKTIVRVSSCGQTGRIGPTPEQCVDQQNGSDALVEVLSGTS 504
Query: 432 ------THPYTGVQVWEVPEEGLYTIIATXXXXXXXXXXXXXXHGAQARALLELHRSELV 485
+ + G+Q W P G YTIIA GA R ++EL + + +
Sbjct: 505 TDEGDASLRFKGIQRWIAPSGGYYTIIAMGARGGAGALSMGVTMGAMVRGVIELEKGQQL 564
Query: 486 YMLIGQQGINACKKTLSAQESQECSRKPSNESLQVFTSKTHEVRNTHVIDXXXXXXXXTF 545
Y ++GQ G +AC K S S N S + + S +V+N D T+
Sbjct: 565 YFMVGQPGTDACPKVRSRGSRSGGSPGGRNASNE-YVSIMKQVKNIEFRDGGGGGGGATY 623
Query: 546 VFLMD--KEGRPFPLVVAXXXXXISVGIFRDDGSQHGKPHTNSTPESGYMYGQPDKTSEY 603
+F + G PL++A + FRDDG QH K T P+ G K +
Sbjct: 624 IFTVSIAPNGEQQPLLIAGGGGGLGPTQFRDDGVQHAKGAT--PPDRAPYNGVSFKKN-- 679
Query: 604 VVLGTGAGGGWVARS 618
G GGGW+A S
Sbjct: 680 ----AGGGGGWIASS 690
>UniRef50_UPI0000DB6D22 Cluster: PREDICTED: similar to Alk CG8250-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to Alk
CG8250-PA - Apis mellifera
Length = 1436
Score = 435 bits (1072), Expect = e-120
Identities = 209/406 (51%), Positives = 271/406 (66%), Gaps = 21/406 (5%)
Query: 704 GPGEVLIIPAIHDCGCDYRCVALNEFRSEVRCYCPSSWVFNPMDPGKCVYPNTWFTVEGE 763
GPGEV IIPAI C CD+RC++L+++ SE +C CP W+ + N +
Sbjct: 727 GPGEVYIIPAISGCDCDFRCISLDQYLSETKCLCPPGWLLSNNSRSCLPDDNVLDGSKVT 786
Query: 764 WSTFTWTIVASSIG------------CXXXXXXXXXXXXXYNRYQKKREARQAQKRIMEQ 811
F ++ SIG C YNRYQ ++ Q ++ +
Sbjct: 787 HQPFMIPLIVVSIGLLFAFTALCLLLCKKLFDNIVTYIVFYNRYQNRKALIQRRQVMFGN 846
Query: 812 EVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAF 871
+L L+ + + FNP+Y F + L Q+ RE + L++ LGQGAF
Sbjct: 847 GTELTSLQAV----SDTIMTEFNPNY---EFAGNLYSFKDLTQIPRECITLIRPLGQGAF 899
Query: 872 GEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCF 931
GEV+QG+YR+R E PVAVK +P S Q E+DF+MEA IM+KFNH NIVH IGV F
Sbjct: 900 GEVFQGVYRYRRNQ--EQPVAVKAIPSSSRPQTEADFMMEALIMSKFNHPNIVHFIGVSF 957
Query: 932 DRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIH 991
+R+P++IVLELLAGG+LKNFLRE RP+ +R ++L M+DL++C DV GC+Y+E RFIH
Sbjct: 958 ERNPKYIVLELLAGGNLKNFLREERPRADRPTSLRMQDLIMCGFDVANGCKYMEEARFIH 1017
Query: 992 RDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFT 1051
RDIAARNCLLTS+GPGR+VKIADFGMA+DIYR+DYY+KGGKAMLPIKWMPPE+++DG+FT
Sbjct: 1018 RDIAARNCLLTSKGPGRIVKIADFGMAKDIYRSDYYRKGGKAMLPIKWMPPESFLDGIFT 1077
Query: 1052 TKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKPYG 1097
TKTDVW+FGVLLWE+ S G +PYTGC NRE M +V+ GGRLEKP G
Sbjct: 1078 TKTDVWAFGVLLWEIMSFGYIPYTGCTNREAMTMVTLGGRLEKPAG 1123
Score = 357 bits (879), Expect = 7e-97
Identities = 216/631 (34%), Positives = 311/631 (49%), Gaps = 68/631 (10%)
Query: 18 CKFEALLHQRMMQNASIRLISESTISEVQWILQEVAGNNAENWYPMRFMIGKVQQEVRII 77
C E L+Q M N I+L+ + + WI E GNN W MRF IG + Q ++I
Sbjct: 78 CILELALYQVEMSNGIIKLLIIT--NNTSWIAAERQGNNHTKWEIMRFTIGTITQSHQLI 135
Query: 78 IEITRPNYVSLAQPLPHIAIDNIRMIDCVPEPPVYNGECNAGQLKCKIMNRESCIKLHQV 137
IEI P S IAIDN+ +IDC PE +C +CK SC+ +V
Sbjct: 136 IEILVPYSNS------SIAIDNVHLIDCFPESTAVRTDCTEDMYRCK---NGSCLNRTRV 186
Query: 138 CDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGFVDVPQPILKWSRHRGPTPTDKTGPN 197
CDL KDC +G DE+ +CDK+P + CNFE CG+ +VP L W+ HRG TP++KTG
Sbjct: 187 CDLTKDCAEGEDEEDDCDKIPENARCNFEHGWCGWKNVPGRPLNWTLHRGATPSEKTG-- 244
Query: 198 YDHTCGPPTQPNLNPTKKVPPLTPPFHMHCAGYYFFVNMNVTGPNKEKADFASTAVMKTV 257
P+ + T + + +G Y +V+M+ K ++ S +++
Sbjct: 245 ----------PSYDHT----------YRNASGTYAYVSMS------PKVEYGSHGTIESP 278
Query: 258 IFNPPPKVHGDVASKYYNCCMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFS--TK 315
++NP P +GD S Y+ C VRF+Y Q G N GSL + +V++ +W+S +
Sbjct: 279 LYNPTPPYNGDPQSPYHKSCQVRFFYHQYGANSGSLGLYLVQVKPHQPHYERLWWSYLSG 338
Query: 316 DKGENWYRASIFLPNVTRRYYLQFKTRMGMRIYSDSAIDDFSMSPECFGLNVDPEELGDY 375
D+ + WY ++ LP++ RY+LQF+ G +D AIDDFS+SPECFG+ V PE +GD+
Sbjct: 339 DRSDVWYNQAVSLPDIKYRYFLQFEASRGYYSKADVAIDDFSLSPECFGIGVPPEVVGDF 398
Query: 376 NYYDPVFDEK--TTPHKDFTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTH 433
NY +PV D + HKDF T CG +GR GPN C+ YN T D+ ++
Sbjct: 399 NYSNPVIDSEKIRVQHKDFVNETVIHITTCGNTGRIGPNSEQCNKEYNRT--DIELVTPS 456
Query: 434 P--------YTGVQVWEVPEEGLYTIIATXXXXXXXXXXXXXXHGAQARALLELHRSELV 485
P G+Q W P G YT+I GA R ++EL + + +
Sbjct: 457 PEEDPLSFNLNGIQRWIAPRGGYYTLIGMGARGGKGSGGMGSTLGALVRGVIELEKGDQL 516
Query: 486 YMLIGQQGINACKKTLSAQESQECSRKPSNESLQVFTSKTHEVRNTHVIDXXXXXXXXTF 545
Y ++GQ G++AC K L Q+ C P S + SK HEVR + D T+
Sbjct: 517 YFMVGQAGMDACPKNL-GQKLDSCQGPPLYGS-SLGASKVHEVRKIKIRDGGGGGGGATY 574
Query: 546 VFLMDKEGRPFPLVVAXXXXXISVGIFRDDGSQHGK--PHTNSTPESG-YMYGQPDKTSE 602
+F + G P+++A + +G F D+G QHG+ P P SG + Q D
Sbjct: 575 IFTLKSNGEQHPILIAGGGGGLGLGQFIDNGHQHGRGPPPPGRQPISGTVLSSQADSPG- 633
Query: 603 YVVLGTGAGGGWVARSGP---ITPGSERVRG 630
G GGG SG T G+ VRG
Sbjct: 634 ------GPGGGLNESSGTGQRTTAGALLVRG 658
>UniRef50_Q4SK07 Cluster: Tyrosine-protein kinase receptor; n=2;
Tetraodontidae|Rep: Tyrosine-protein kinase receptor -
Tetraodon nigroviridis (Green puffer)
Length = 1084
Score = 348 bits (856), Expect = 4e-94
Identities = 165/300 (55%), Positives = 215/300 (71%), Gaps = 9/300 (3%)
Query: 796 QKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQV 855
+K E + Q + + +L +LR + D +NP+Y F + V L +V
Sbjct: 444 RKHTELQSIQLELQSPDCKLSKLRASTIMTD------YNPNY---CFAGKTASVNDLKEV 494
Query: 856 SRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIM 915
SR ++ L + LG GAFGEVY+GL + + + VAVKTLPE+ + Q E DFLMEA I+
Sbjct: 495 SRRNISLTRGLGHGAFGEVYEGLAVGIPGEPSPLQVAVKTLPEVCSEQDELDFLMEALII 554
Query: 916 AKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSV 975
+KF+H NIV +GV PRFI+LEL+ GGDLK F+RE+RP+PE S+LTM DLL +
Sbjct: 555 SKFSHQNIVRCVGVSLQAMPRFILLELMTGGDLKTFMRETRPRPEHPSSLTMVDLLNIAR 614
Query: 976 DVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAML 1035
D+ KGC+YLE +FIHRDIAARNCLLT +GPGRV KI DFGMARDIYRA YY+KGG+AML
Sbjct: 615 DIAKGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRASYYRKGGRAML 674
Query: 1036 PIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
P+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++ P
Sbjct: 675 PVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSRSNQEVLEFVTNGGRMDPP 734
Score = 73.7 bits (173), Expect = 3e-11
Identities = 66/226 (29%), Positives = 90/226 (39%), Gaps = 16/226 (7%)
Query: 400 FTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVWEVPEEGLYTIIATXXXXX 459
F CGA G GP T C +Y V V V P G+Q W+V E G Y I A
Sbjct: 3 FQTCGARGPEGPTHTQCLNSYRKNNVSVTVAAQGPLKGIQKWKVLETGTYRITAYGAAGG 62
Query: 460 XXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINACKKTLSAQESQECSRKPSNESLQ 519
HG L + E +Y+L+GQQG +AC ++ S C + +N +
Sbjct: 63 RSVLVMSRSHGVYLAGDFWLKKGEELYILVGQQGEDAC-PSVKISSSLICLLQSNNILNK 121
Query: 520 VFTSKTHE-VRNTHVIDXXXXXXXXTFVFLMDKEGRPFPLVVAXXXXXISVGIFRDDGSQ 578
+ ++ V T V T+VF +D G PL++A G R SQ
Sbjct: 122 ICQEQSGPMVNKTQVKWGGGGGGGATYVFKVD-NGVYVPLIIAAG------GGGRGYSSQ 174
Query: 579 HGKPHTNSTPESGYMYGQPDKTSEYVVLGTGAGGGWVARSGPITPG 624
ES +G+ K+ G GGGW S PI+ G
Sbjct: 175 AETQLEQMDYESS-QHGRNGKS-----YAAGGGGGW-NDSAPISQG 213
>UniRef50_UPI0000F2052A Cluster: PREDICTED: similar to anaplastic
lymphoma kinase (Ki-1),; n=1; Danio rerio|Rep: PREDICTED:
similar to anaplastic lymphoma kinase (Ki-1), - Danio
rerio
Length = 1387
Score = 345 bits (848), Expect = 4e-93
Identities = 183/394 (46%), Positives = 245/394 (62%), Gaps = 15/394 (3%)
Query: 704 GPGEVLIIPAIHDCGCDYRCVALNEFRSEVRCYCPSSWVFNPMDPGKCVYPNTWFTVEGE 763
G GEV+I P + C+ +E + CYC P D C+ +T +
Sbjct: 650 GNGEVIINPVQNCSHCESG--DCHETSEGMVCYCDEELTLAP-DGVSCIN-STELPLLPA 705
Query: 764 WSTFTWTIVASSIGCXXXXXXXXXXXXXYN-RYQKKR-EARQAQKRIMEQEVQLHRLRNA 821
+ + + S+G Y++K E + Q + + +L +LR +
Sbjct: 706 QPSLSHLALGLSVGTSALIAALLLAVSGVMIMYRRKHTELQSIQLELQSPDCKLSKLRAS 765
Query: 822 PGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRH 881
D +NP+Y F + V L +V R ++ L + LG GAFGEVY+GL
Sbjct: 766 TIMTD------YNPNY---CFGGKTASVNDLKEVPRRNISLTRGLGHGAFGEVYEGLAVG 816
Query: 882 RSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLE 941
+ + M VAVKTLPE+ + Q E DFLMEA I++KF+H NIV IGV P FI+LE
Sbjct: 817 IPGEPSPMQVAVKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHFILLE 876
Query: 942 LLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLL 1001
L+AGGDLK+FLRE+RP+ E S+LTM DLL + D+ +GC+YLE +FIHRDIAARNCLL
Sbjct: 877 LMAGGDLKSFLRETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLL 936
Query: 1002 TSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGV 1061
T +GPGRV KI DFGMARDIYRA YY+KGG+AMLP+KWMPPEA+++G+FT+KTD WSFGV
Sbjct: 937 TCKGPGRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGV 996
Query: 1062 LLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
LLWE+FSLG MPY +N+EV+E V+ GGR++ P
Sbjct: 997 LLWEIFSLGYMPYPSRSNQEVLEFVTNGGRMDPP 1030
Score = 102 bits (244), Expect = 6e-20
Identities = 71/234 (30%), Positives = 110/234 (47%), Gaps = 15/234 (6%)
Query: 277 CMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFSTKDK--GENWYRASIFLPNVTRR 334
CMV+F+ G + G+LS+ + E + S+W ST + G+ W ++ L +
Sbjct: 239 CMVKFWVC--GSSNGALSLWITENSTGPEGQRSLWNSTSEANMGKGWKLITLPLFGLVDL 296
Query: 335 YYLQFKTRMGMRIYSDSAIDDFSMSPECF-GLNVDPEELGDYNYYDPVFDE-----KTTP 388
+YLQF + A+D+F++S ECF N + + + +F + KTT
Sbjct: 297 FYLQFSADISSSSGIAFAVDNFTLSMECFLETNGEFPPVAPISPTQALFTQSNENIKTTT 356
Query: 389 HK-----DFTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVWEV 443
T V + F CGA+G+ GP T C +Y NT V+V V P+ G+Q+W+V
Sbjct: 357 TLYGGPGASTESVKWIFHTCGATGQDGPTPTQCSNSYRNTNVNVTVGTKGPFKGIQMWQV 416
Query: 444 PEEGLYTIIATXXXXXXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINAC 497
PE Y I A HG L + EL+Y+L+GQ+G +AC
Sbjct: 417 PETRKYRITAYGAAGGRSVLAVHKSHGVYMTGDFLLQKDELLYILVGQEGEDAC 470
Score = 48.8 bits (111), Expect = 8e-04
Identities = 20/54 (37%), Positives = 30/54 (55%)
Query: 132 IKLHQVCDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGFVDVPQPILKWSRH 185
I + Q+CD DC G DE ++C + GSYC+F ++ CG+ V +W H
Sbjct: 139 INVSQLCDFSIDCPQGDDEGEHCRQFLNGSYCSFGREDCGWQPVQGRGPQWRAH 192
>UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; Homo
sapiens|Rep: Tyrosine-protein kinase receptor - Homo
sapiens (Human)
Length = 1310
Score = 345 bits (847), Expect = 5e-93
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 749 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 799
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 800 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 859
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 860 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 919
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 920 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 979
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 980 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 1039
Query: 1094 KP 1095
P
Sbjct: 1040 PP 1041
>UniRef50_Q9UM73 Cluster: ALK tyrosine kinase receptor precursor;
n=37; Euteleostomi|Rep: ALK tyrosine kinase receptor
precursor - Homo sapiens (Human)
Length = 1620
Score = 345 bits (847), Expect = 5e-93
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 1059 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 1109
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 1110 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 1169
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 1170 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 1229
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 1230 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 1289
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 1290 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 1349
Query: 1094 KP 1095
P
Sbjct: 1350 PP 1351
Score = 95.9 bits (228), Expect = 5e-18
Identities = 93/372 (25%), Positives = 152/372 (40%), Gaps = 36/372 (9%)
Query: 277 CMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFSTKDKGEN-WYRASIFLPNVTRRY 335
C +R + G G++S+ +VE VW +G + W + L +V+ R+
Sbjct: 548 CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRF 607
Query: 336 YLQFKTRMGMRIYSDSAIDDFSMSPECFGLNVDPEE------------LGDYNYYDPVFD 383
+LQ G + A D+ S+S +C+ L + E+ L + N +
Sbjct: 608 WLQMVAWWGQGSRAIVAFDNISISLDCY-LTISGEDKILQNTAPKSRNLFERNPNKELKP 666
Query: 384 EKTTPHKD--FTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVW 441
+ +P + F V++ FT CGASG +GP Q C+ AY N+ + V V P G+Q+W
Sbjct: 667 GENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIW 726
Query: 442 EVPEEGLYTIIA-TXXXXXXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINACKKT 500
+VP Y+I HG + L + +++Y+L+GQQG +AC T
Sbjct: 727 KVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPST 786
Query: 501 LSAQESQECSRKPSNESLQVFTSKTHEVRNTHV-IDXXXXXXXXTFVFLMDKEGRPFPLV 559
+ +K V + R+ H T+VF M K+G P PL+
Sbjct: 787 ------NQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKM-KDGVPVPLI 839
Query: 560 VAXXXXXISVGIFRDDGSQHGKPHTNSTPESGYMYGQPDKTSEYVVLGTGAGGGWVARSG 619
+A + G D + H + N++ G + G G GGGW +
Sbjct: 840 IAAGGGGRAYGAKTD--TFHPERLENNSSVLG-LNGNSG--------AAGGGGGWNDNTS 888
Query: 620 PITPGSERVRGA 631
+ G GA
Sbjct: 889 LLWAGKSLQEGA 900
Score = 54.8 bits (126), Expect = 1e-05
Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 12/168 (7%)
Query: 6 VKSPPFRGLWEFCKFEALLHQRMMQNAS-IRLISESTISEVQWILQEVAGNNAENWYPMR 64
+ SP R E C +H+ + + I + + + +L G + W ++
Sbjct: 333 ILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAAREILLMPTPGKHG--WTVLQ 390
Query: 65 FMIGKVQQEVRIIIEITRPNYVSLAQPLPHIAIDNIRMIDCVPEPPVYNGECNAGQLKCK 124
IG+ R+ +E SL+ A+D + +C G A Q
Sbjct: 391 GRIGRPDNPFRVALEYISSGNRSLS------AVDFFALKNC--SEGTSPGSKMALQSSFT 442
Query: 125 IMNRESCIKLHQVCDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGF 172
N + ++L Q CD +DC G DE + C K+P G YCNFE CG+
Sbjct: 443 CWNG-TVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGW 489
>UniRef50_Q8JFV0 Cluster: Tyrosine-protein kinase receptor; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase receptor -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1161
Score = 339 bits (834), Expect = 2e-91
Identities = 161/301 (53%), Positives = 213/301 (70%), Gaps = 9/301 (2%)
Query: 795 YQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQ 854
Y+KK + R+ E +L ++R++ D +NP+YG + + + L +
Sbjct: 510 YRKKNHLHAVRIRLQSPEYKLSKIRSSTIMTD------YNPNYG---YFGKAASLSELKE 560
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
V R+++ L++ALG GAFGEVY+G + + M VA+KTLPE+ + Q E DFLMEA I
Sbjct: 561 VPRKNITLLRALGHGAFGEVYEGQVLGMNGENTAMQVAIKTLPEICSEQDEMDFLMEALI 620
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M+KF+H NIV IGV PRFI+LEL+ GGD+K+FLR +RP+ +S+L+M +LL +
Sbjct: 621 MSKFSHQNIVRCIGVSLQILPRFILLELMTGGDMKSFLRLNRPRTNHSSSLSMLELLHMA 680
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
D+ GCRYLE FIHRDIAARNCLLT GP RV KI DFGMARDIYRA YY+KGG+AM
Sbjct: 681 RDIALGCRYLEENHFIHRDIAARNCLLTCPGPDRVAKIGDFGMARDIYRASYYRKGGRAM 740
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
LP+KWMPPEA+++G+FT KTD WSFGVLLWE+FSLG MPY N+EV+E V+GGGR++
Sbjct: 741 LPVKWMPPEAFLEGIFTCKTDTWSFGVLLWEIFSLGYMPYPCKTNQEVLEFVTGGGRMDP 800
Query: 1095 P 1095
P
Sbjct: 801 P 801
Score = 81.0 bits (191), Expect = 2e-13
Identities = 41/99 (41%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 400 FTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVWEVPEEGLYTIIA-TXXXX 458
FT CGASG +GP Q CD+AY NT V V V P GVQ+W+VP Y I A
Sbjct: 102 FTSCGASGPFGPTQAQCDSAYRNTNVSVVVGKEGPLRGVQMWKVPATNTYKISAYGAAGG 161
Query: 459 XXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINAC 497
HG A L + +++Y+LIG QG +AC
Sbjct: 162 KGAKNHNKRSHGVFISATFPLEKGDILYILIGHQGEDAC 200
>UniRef50_A6NNJ8 Cluster: Uncharacterized protein LTK; n=12;
Euarchontoglires|Rep: Uncharacterized protein LTK - Homo
sapiens (Human)
Length = 803
Score = 328 bits (807), Expect = 4e-88
Identities = 161/304 (52%), Positives = 214/304 (70%), Gaps = 9/304 (2%)
Query: 796 QKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLP-QGIDVR-GLP 853
QKK + Q + R+ E++L +LR + A+ A NP+Y P Q + G+
Sbjct: 390 QKKWQGLQ-EMRLPSPELELSKLRTS------AIRTAPNPYYCQVGLGPAQSWPLPPGVT 442
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+VS ++ L++ALG GAFGEVY+GL D++ + VA+KTLPEL + Q E DFLMEA
Sbjct: 443 EVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEAL 502
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KF H NIV +G+ PR I+LEL++GGD+K+FLR SRP + S L M+DLL
Sbjct: 503 IISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQL 562
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ +GC YLE FIHRDIAARNCLL+ GP RV KI DFGMARDIYRA YY++G +A
Sbjct: 563 AQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRA 622
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+LP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY G N+EV++ V GGGR++
Sbjct: 623 LLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMD 682
Query: 1094 KPYG 1097
P G
Sbjct: 683 PPRG 686
Score = 79.8 bits (188), Expect = 4e-13
Identities = 42/99 (42%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Query: 400 FTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVWEVPEEGLYTIIA-TXXXX 458
F+ CGASGR+GP QT CD AY T V V V GVQ+W VP G Y I A
Sbjct: 70 FSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGG 129
Query: 459 XXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINAC 497
HG A+ L E +Y+L+GQQG +AC
Sbjct: 130 KGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDAC 168
>UniRef50_P08923 Cluster: Leukocyte tyrosine kinase receptor
precursor; n=8; Amniota|Rep: Leukocyte tyrosine kinase
receptor precursor - Mus musculus (Mouse)
Length = 888
Score = 326 bits (802), Expect = 2e-87
Identities = 156/291 (53%), Positives = 210/291 (72%), Gaps = 8/291 (2%)
Query: 807 RIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLP-QGIDVR-GLPQVSRESLKLVK 864
R+ E++L +LR++ A+ A NP+Y P Q + GL +VS ++ L++
Sbjct: 457 RLPGPELELSKLRSS------AIRTAPNPYYCQVGLSPAQPWPLPPGLTEVSPANVTLLR 510
Query: 865 ALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIV 924
ALG GAFGEVY+GL D++ +PVA+KTLPEL + Q E DFLMEA I++KF+H NIV
Sbjct: 511 ALGHGAFGEVYEGLVTGLPGDSSPLPVAIKTLPELCSHQDELDFLMEALIISKFSHQNIV 570
Query: 925 HLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYL 984
+G+ F PR I+LEL++GGD+K+FLR SRP P + + LTM+DLL + D+ +GC YL
Sbjct: 571 RCVGLSFRSAPRLILLELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHYL 630
Query: 985 ETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEA 1044
E FIHRDIAARNCLL+ G RV KI DFGMARDIY+A YY+KGG+ +LP+KWMPPEA
Sbjct: 631 EENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEA 690
Query: 1045 YIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
++G+FT+KTD WSFGVLLWE+FSLG MPY G N+EV++ ++ G R++ P
Sbjct: 691 LLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMDPP 741
Score = 83.4 bits (197), Expect = 3e-14
Identities = 72/234 (30%), Positives = 90/234 (38%), Gaps = 14/234 (5%)
Query: 400 FTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVWEVPEEGLYTIIA-TXXXX 458
F CGASGR GP QT CD AY + V V V P GVQ+W P+ G Y I A
Sbjct: 70 FNTCGASGRSGPTQTQCDGAYTGSSVMVTVGAAGPLKGVQLWRAPDTGQYLISAYGAAGG 129
Query: 459 XXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINACKKTLSAQESQECSRKPSNESL 518
HG A+ L R E VY+L+GQQG +AC + ESQ S E
Sbjct: 130 KGAQNHLSRAHGIFLSAVFFLRRGEPVYILVGQQGQDACPG--GSPESQLVCLGESGEHA 187
Query: 519 QVF-TSKTHEVRNTHVIDXXXXXXXXTFVFLMDKEGRPFPLVVAXXXXXISVGIFRDDGS 577
+ T + R T +F + + G P PL+VA S D G
Sbjct: 188 TTYGTERIPGWRRW--AGGGGGGGGATSIFRL-RAGEPEPLLVAAGGGGRSYRRRPDRGR 244
Query: 578 QHGKPHTNSTPESGYMYGQPDKTSEYVVLGTGAGGGWVARSGPITPGSERVRGA 631
P T + G + G G GW +R+ G GA
Sbjct: 245 TQAVPERLETRAAAPGSGGRGGAA-------GGGSGWTSRAHSPQAGRSPREGA 291
>UniRef50_P00529 Cluster: Tyrosine-protein kinase transforming protein
ros; n=3; root|Rep: Tyrosine-protein kinase transforming
protein ros - Avian sarcoma virus (strain UR2)
Length = 402
Score = 287 bits (703), Expect = 2e-75
Identities = 145/308 (47%), Positives = 206/308 (66%), Gaps = 10/308 (3%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R++ ++ A Q +++++ +L +LR G + +A N Y + S LP ++
Sbjct: 36 HQRWKSRKPASTGQIVLVKEDKELAQLR----GMAETVGLA-NACY-AVSTLPSQAEIES 89
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAA-EMPVAVKTLPELSTGQAESDFLM 910
LP R+ L L K LG GAFGEVY+G AD + E VAVKTL +T Q +S+FL
Sbjct: 90 LPAFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLK 149
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KF+H +I+ L+GVC P++++LEL+ GGDL ++LR +R + ++ LT+ DL
Sbjct: 150 EAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQSPLLTLTDL 209
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPG---RVVKIADFGMARDIYRADYY 1027
L +D+CKGC YLE RFIHRD+AARNCL++ + G RVVKI DFG+ARDIY+ DYY
Sbjct: 210 LDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYKNDYY 269
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
+K G+ +LP++WM PE+ IDGVFT +DVW+FGVL+WE +LG PY G +N EV+ V
Sbjct: 270 RKRGEGLLPVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVR 329
Query: 1088 GGGRLEKP 1095
GGRLE P
Sbjct: 330 SGGRLESP 337
>UniRef50_UPI0000DB6C99 Cluster: PREDICTED: similar to proto-oncogene
c-ros-1 protein precursor; n=1; Apis mellifera|Rep:
PREDICTED: similar to proto-oncogene c-ros-1 protein
precursor - Apis mellifera
Length = 2105
Score = 276 bits (677), Expect = 2e-72
Identities = 138/303 (45%), Positives = 197/303 (65%), Gaps = 9/303 (2%)
Query: 795 YQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQ 854
Y++++E ++A + +V+L LR P GN + N Y S L D LP+
Sbjct: 1748 YRQRKEDKKAVLPPLVSDVELATLREIPRGN----FVQSNALYAST--LQNDSDDSTLPK 1801
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ RE + L K LG GAFGEV+QG + PVA+KTL + ++ Q +++FL EA +
Sbjct: 1802 IRREQITLAKFLGSGAFGEVFQGNAKDLERPGIT-PVAIKTLRKGASAQEKTEFLQEARL 1860
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-KPERASALTMKDLLLC 973
M+ F H +++ L+GVC D P +VLEL+ GDL ++LR SR +P + AL ++DLL
Sbjct: 1861 MSHFRHKHVLRLLGVCLDTDPPLLVLELMEAGDLLSYLRASRSLQPSDSHALRLQDLLAM 1920
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRG-PGRVVKIADFGMARDIYRADYYKKGGK 1032
DV +GCRYLE F+HRD+A RNCL++++ RVVKI DFG+ARDIY+ DYY+K G+
Sbjct: 1921 CEDVARGCRYLEELHFVHRDLACRNCLVSAKDRENRVVKIGDFGLARDIYKNDYYRKEGE 1980
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
+LP++WM PE+ +DGVFT+++DVW+FGVL+WE+ SLG PY N EV+ V GGRL
Sbjct: 1981 GLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQQPYPARTNIEVLHHVRAGGRL 2040
Query: 1093 EKP 1095
KP
Sbjct: 2041 SKP 2043
>UniRef50_Q170Z1 Cluster: Tyrosine-protein kinase receptor; n=1; Aedes
aegypti|Rep: Tyrosine-protein kinase receptor - Aedes
aegypti (Yellowfever mosquito)
Length = 2073
Score = 274 bits (671), Expect = 1e-71
Identities = 127/247 (51%), Positives = 175/247 (70%), Gaps = 4/247 (1%)
Query: 852 LPQVSRESLKLVKA--LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFL 909
LPQ+ RE + + + LG GAFGEVY+G+ + +A E VA+KTL + +T Q +++FL
Sbjct: 1802 LPQIRREQISMTSSPFLGSGAFGEVYEGIVKGVGGEA-ETRVAIKTLRKGATEQEKAEFL 1860
Query: 910 MEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKD 969
EA +M+ F H +I+ LIGVC D +IV+EL+ GGDL ++LR +RP P S LT+ D
Sbjct: 1861 QEAHLMSNFKHKHILKLIGVCLDLDSLYIVMELMQGGDLLSYLRSNRPTPGNPSMLTLLD 1920
Query: 970 LLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGP-GRVVKIADFGMARDIYRADYYK 1028
L+ VDV GCRYLE F+HRD+A RNCL++S P RVVKI DFG+ARDIY+ DYY+
Sbjct: 1921 LISMCVDVATGCRYLEEMHFVHRDLACRNCLVSSMDPRERVVKIGDFGLARDIYKNDYYR 1980
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DGVFT+++D+W+FGVLLWE+ +LG PY N EV+ V
Sbjct: 1981 KEGEGLLPVRWMSPESLVDGVFTSQSDIWAFGVLLWEIMTLGQQPYPARNNVEVLHYVRD 2040
Query: 1089 GGRLEKP 1095
GGRL +P
Sbjct: 2041 GGRLTRP 2047
>UniRef50_P08922 Cluster: Proto-oncogene tyrosine-protein kinase ROS
precursor; n=20; Eumetazoa|Rep: Proto-oncogene
tyrosine-protein kinase ROS precursor - Homo sapiens
(Human)
Length = 2347
Score = 269 bits (660), Expect = 2e-70
Identities = 136/307 (44%), Positives = 196/307 (63%), Gaps = 9/307 (2%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R + ++ A++ ++ ++ +L LR G + +A N Y + LP ++
Sbjct: 1883 HRRLKNQKSAKEGVTVLINEDKELAELRGLAAG----VGLA-NACYAIHT-LPTQEEIEN 1936
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLM 910
LP RE L L LG GAFGEVY+G + E+ VAVKTL + ST Q + +FL
Sbjct: 1937 LPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK 1996
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KFNH NI+ +GVC P++I+LEL+ GGDL +LR++R LT+ DL
Sbjct: 1997 EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDL 2056
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRG--PGRVVKIADFGMARDIYRADYYK 1028
+ VD+ KGC YLE FIHRD+AARNCL++ + R+VKI DFG+ARDIY+ DYY+
Sbjct: 2057 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYR 2116
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DG+FTT++DVWSFG+L+WE+ +LG PY +N +V+ V
Sbjct: 2117 KRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQT 2176
Query: 1089 GGRLEKP 1095
GGRLE P
Sbjct: 2177 GGRLEPP 2183
>UniRef50_UPI0000E471D0 Cluster: PREDICTED: similar to p80 protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to p80 protein, partial -
Strongylocentrotus purpuratus
Length = 526
Score = 268 bits (658), Expect = 4e-70
Identities = 116/181 (64%), Positives = 147/181 (81%)
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M F+H N+V L+G+CF P FIVLE + GG+LK FLR+ RP E+ S++TMKDLL +
Sbjct: 1 MGNFDHPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEEKPSSITMKDLLQIT 60
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
DV +GCRYLE++RFIHRDIAARN LLT++ GR KIADFGMARDIYRADYY+KGG+A+
Sbjct: 61 QDVAQGCRYLESRRFIHRDIAARNILLTTKESGRAAKIADFGMARDIYRADYYRKGGQAL 120
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
LP+KWMPPEA+ DG+FT+KTDVW++GVLLWE+ SLG MPY G +N+EV++ VS G R+
Sbjct: 121 LPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPGMSNQEVIQFVSAGERMNP 180
Query: 1095 P 1095
P
Sbjct: 181 P 181
>UniRef50_Q5TUS8 Cluster: Tyrosine-protein kinase receptor; n=1;
Anopheles gambiae str. PEST|Rep: Tyrosine-protein kinase
receptor - Anopheles gambiae str. PEST
Length = 2075
Score = 257 bits (629), Expect = 1e-66
Identities = 128/287 (44%), Positives = 183/287 (63%), Gaps = 8/287 (2%)
Query: 812 EVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKA--LGQG 869
+V+L LR P + N Y S S I + LP++ + + + + LG G
Sbjct: 1759 DVELANLRELPRRGN--FVQTTNILYSSGSMTDSEIAL--LPRIRLDQIFMASSSLLGSG 1814
Query: 870 AFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGV 929
AFGEVY+G+ + +A E VA+KTL + + + +FL EA +M+ F H +I L+GV
Sbjct: 1815 AFGEVYEGVVKGVDGEA-ETRVAIKTLKKGAKLHEKQEFLQEAQLMSNFKHKHITRLLGV 1873
Query: 930 CFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRF 989
C + I++EL+ GGDL ++LR SR P +A+ LTM DL+ DV GCRYLE F
Sbjct: 1874 CLEADALLIIMELMQGGDLLSYLRRSRSLPGQAARLTMLDLISMCQDVASGCRYLEEMHF 1933
Query: 990 IHRDIAARNCLLTSRGP-GRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDG 1048
+HRD+A RNCL++S P RVVKI DFG+ARDIY+ DYY+K G+ +LP++WM PE+ +DG
Sbjct: 1934 VHRDLACRNCLVSSTDPRDRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMSPESLVDG 1993
Query: 1049 VFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
VFT+++D+W+FGVLLWE+ +LG PY N EV+ V GG L++P
Sbjct: 1994 VFTSQSDIWAFGVLLWEIMTLGEQPYQAKNNVEVLNHVREGGHLDRP 2040
>UniRef50_O76411 Cluster: Suppressor of constitutive dauer formation
protein 2; n=2; Caenorhabditis|Rep: Suppressor of
constitutive dauer formation protein 2 - Caenorhabditis
elegans
Length = 1446
Score = 256 bits (626), Expect = 3e-66
Identities = 132/261 (50%), Positives = 173/261 (66%), Gaps = 12/261 (4%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPE-LSTGQA-ESDFL 909
LP +SR+S++ + LG+G FGEVY G Y + + +AVK + S QA +SDF
Sbjct: 993 LPSISRDSIERGRVLGRGNFGEVYYGEY-------SGVKLAVKMISRTFSASQASQSDFC 1045
Query: 910 MEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTM 967
EA M F N+V LIG+ F++ P I LE + GGDL +F++E RP + L M
Sbjct: 1046 NEALCMGTFVDENVVRLIGIDFEKVPYMIALEYMEGGDLLSFVKECRPNQVSLNPFQLAM 1105
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI-YRADY 1026
DL+ DV GC+ LET ++HRDIAARN LLT+RGP RV KIADFGMA++I Y +Y
Sbjct: 1106 SDLIKICCDVAAGCKCLETFGYVHRDIAARNILLTTRGPQRVAKIADFGMAKEITYGTEY 1165
Query: 1027 YKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
Y+ G+ M+PIKW PPEA+IDGVFTTK+D+WSFGVL WEVFSLGV+PY N EVM ++
Sbjct: 1166 YRINGRTMMPIKWTPPEAFIDGVFTTKSDIWSFGVLCWEVFSLGVVPYPNRRNEEVMLML 1225
Query: 1087 SGGGRLEKPYGEGSEYHKFKR 1107
+ G RLE PYG + ++ R
Sbjct: 1226 TEGARLEYPYGIPTRVYQLMR 1246
Score = 37.9 bits (84), Expect = 1.5
Identities = 41/154 (26%), Positives = 69/154 (44%), Gaps = 13/154 (8%)
Query: 24 LHQRMMQNASIRLISESTIS--EVQWILQEVAGNNAENWYPMRFMIGKVQQEVRIIIEIT 81
+H Q+++ RL+ S + E + + + + W P++ IG + +I I+
Sbjct: 232 MHHFTHQSSTSRLVVRSILQSGEKKNLYEHWLKPASVFWVPVQVAIGSYAEPFKISIDCE 291
Query: 82 R--PNYVSLAQPLPHIAIDNIRMIDCVP-EPPVYNGECNAG-QLKCKIMNRESCIKLHQV 137
P +P +I +I +C P+ +C+ G Q C I C++ Q
Sbjct: 292 TGFPPKKKKNKPFT-CSIADIYFENCGEIRDPIE--QCSRGDQFLCSISANTRCLQNAQ- 347
Query: 138 CDLVKDCDDGSDEQKNCDKMPYGSYCNFE-QDSC 170
CD DCDD SDE +C + G+ C+F QD C
Sbjct: 348 CDSRIDCDDESDEM-DCGNI-NGTMCDFNGQDYC 379
>UniRef50_Q9Y1Y9 Cluster: Protein tyrosine kinase; n=3; Metazoa|Rep:
Protein tyrosine kinase - Ephydatia fluviatilis
Length = 2069
Score = 254 bits (622), Expect = 1e-65
Identities = 123/273 (45%), Positives = 179/273 (65%), Gaps = 6/273 (2%)
Query: 827 NALAMAFNPHYG--SESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRH-RS 883
N A + NP Y + ++ D+ L + R +LKL + +G FGEV+QG
Sbjct: 1667 NVKAYSSNPQYAWSRDDYICTDEDLELLQKFPRGNLKLENFIDRGEFGEVFQGTATDILG 1726
Query: 884 ADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELL 943
+PVAVKTL + + + + FL EAA+M FNH NIV ++GVC + P +I++EL+
Sbjct: 1727 PGTGPIPVAVKTLRKGAIIEEQKKFLAEAALMGNFNHPNIVKVLGVCVENDPVYIIMELM 1786
Query: 944 AGGDLKNFLRESRPKPERASAL-TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLT 1002
GGDL +FLR++ K ER L T+K+L+ ++DV +GC YL+ FIHRD+AARNCL++
Sbjct: 1787 PGGDLLHFLRDA--KVERGPPLLTVKELIQIALDVAQGCHYLQQTHFIHRDLAARNCLVS 1844
Query: 1003 SRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVL 1062
S+G RVVKI DFG+A+D+Y +DYY+ G+ LP++WM PEA + G F ++DVWSFGVL
Sbjct: 1845 SKGADRVVKIGDFGLAKDLYSSDYYQVEGQRKLPVRWMAPEALLQGKFNMESDVWSFGVL 1904
Query: 1063 LWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+WE+ + G PY N+EV++ V+ GRL+KP
Sbjct: 1905 MWEIMTFGNQPYPALNNQEVLQFVTAEGRLQKP 1937
>UniRef50_O76148 Cluster: Tyrosine-protein kinase receptor; n=1;
Anopheles sp.|Rep: Tyrosine-protein kinase receptor -
Anopheles sp
Length = 863
Score = 248 bits (607), Expect = 7e-64
Identities = 116/247 (46%), Positives = 169/247 (68%), Gaps = 5/247 (2%)
Query: 852 LPQVSRESLKLVKA--LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFL 909
LP++ + + + + LG GAFGEVY+G+ + +A E VA+KTL + + + +FL
Sbjct: 441 LPRIRLDQIFMASSSLLGSGAFGEVYEGVVKGVDGEA-ETRVAIKTLKKGAKLHEKQEFL 499
Query: 910 MEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKD 969
EA +M+ F H +I L+GVC + I++EL+ GGDL ++L ++P P +A+ LTM D
Sbjct: 500 QEAQLMSNFKHKHITRLLGVCLEADALLIIMELMQGGDLLSYL-PAQPLPGQAARLTMLD 558
Query: 970 LLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGP-GRVVKIADFGMARDIYRADYYK 1028
L+ DV GCRYLE F+HRD+A RNCL++S P RVVKI DFG+ARDIY+ DYY+
Sbjct: 559 LISMCQDVASGCRYLEEMHFVHRDLACRNCLVSSTDPRDRVVKIGDFGLARDIYKNDYYR 618
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DGVFT+++D+W+FGVLLWE+ +LG PY N EV+ V
Sbjct: 619 KEGEGLLPVRWMSPESLVDGVFTSQSDIWAFGVLLWEIMTLGEQPYQAKNNVEVLNHVRE 678
Query: 1089 GGRLEKP 1095
GG L++P
Sbjct: 679 GGHLDRP 685
>UniRef50_P06213 Cluster: Insulin receptor precursor (EC 2.7.10.1)
(IR) (CD220 antigen) [Contains: Insulin receptor subunit
alpha; Insulin receptor subunit beta]; n=100;
Euteleostomi|Rep: Insulin receptor precursor (EC
2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin
receptor subunit alpha; Insulin receptor subunit beta] -
Homo sapiens (Human)
Length = 1382
Score = 243 bits (594), Expect = 2e-62
Identities = 123/287 (42%), Positives = 177/287 (61%), Gaps = 7/287 (2%)
Query: 813 VQLHRLRNAPGGNDNALAMAFNPHYGSES-FLPQGIDVRGLPQVSRESLKLVKALGQGAF 871
+ L + P G L + NP Y S S P + V +VSRE + L++ LGQG+F
Sbjct: 975 IYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSF 1034
Query: 872 GEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCF 931
G VY+G R AE VAVKT+ E ++ + +FL EA++M F ++V L+GV
Sbjct: 1035 GMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS 1094
Query: 932 DRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKR 988
P +V+EL+A GDLK++LR RP+ E T+++++ + ++ G YL K+
Sbjct: 1095 KGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKK 1154
Query: 989 FIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDG 1048
F+HRD+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DG
Sbjct: 1155 FVHRDLAARNCMVAH---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDG 1211
Query: 1049 VFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
VFTT +D+WSFGV+LWE+ SL PY G +N +V++ V GG L++P
Sbjct: 1212 VFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQP 1258
>UniRef50_P13368 Cluster: Protein sevenless; n=20; Eumetazoa|Rep:
Protein sevenless - Drosophila melanogaster (Fruit fly)
Length = 2554
Score = 243 bits (594), Expect = 2e-62
Identities = 116/256 (45%), Positives = 171/256 (66%), Gaps = 11/256 (4%)
Query: 848 DVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESD 907
D+ LPQ++ LKL++ LG GAFGEVY+G + ++ + VA+K+L + ++ AE
Sbjct: 2197 DIALLPQINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEEPQR-VAIKSLRKGASEFAE-- 2253
Query: 908 FLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----KPERAS 963
L EA +M+ F H NIV L+G+CFD +++E + GDL ++LR +R +P+ +
Sbjct: 2254 LLQEAQLMSNFKHENIVCLVGICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTA 2313
Query: 964 ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLT----SRGPGRVVKIADFGMAR 1019
L++ +LL +DV GC YLE F+HRD+A RNCL+T S R VKI DFG+AR
Sbjct: 2314 GLSLSELLAMCIDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLAR 2373
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
DIY++DYY+K G+ +LP++WM PE+ +DG+FTT++DVW+FGVL WE+ +LG PY N
Sbjct: 2374 DIYKSDYYRKEGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNN 2433
Query: 1080 REVMELVSGGGRLEKP 1095
EV+ V GGRL++P
Sbjct: 2434 FEVLAHVKEGGRLQQP 2449
>UniRef50_O73798 Cluster: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (xIGF- 1R) (xIGFR) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain]; n=25;
Euteleostomi|Rep: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (xIGF- 1R) (xIGFR) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain] -
Xenopus laevis (African clawed frog)
Length = 1358
Score = 240 bits (587), Expect = 2e-61
Identities = 120/282 (42%), Positives = 175/282 (62%), Gaps = 14/282 (4%)
Query: 819 RNAPGGNDNALAMAFNPHYGS--ESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQ 876
RN+ + L + NP Y S E ++P +V RE + + + LGQG+FG VY+
Sbjct: 958 RNSNRLGNGVLYASVNPEYFSAAEMYVPDKWEV------PREKITMNRELGQGSFGMVYE 1011
Query: 877 GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPR 936
G+ + D AE VA+KT+ E ++ + +FL EA++M +FN ++V L+GV P
Sbjct: 1012 GIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPT 1071
Query: 937 FIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKRFIHRD 993
+++EL+ GDLK++LR RP E S ++K ++ + ++ G YL +F+HRD
Sbjct: 1072 LVIMELMTRGDLKSYLRSLRPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRD 1131
Query: 994 IAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTK 1053
+AARNC++T VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DGVFTT
Sbjct: 1132 LAARNCMVTE---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTN 1188
Query: 1054 TDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+DVWSFGV+LWE+ +L PY G +N +V+ V GG LEKP
Sbjct: 1189 SDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKP 1230
>UniRef50_P08069 Cluster: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (Insulin-like growth factor I
receptor) (IGF-I receptor) (CD221 antigen) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain]; n=47;
Euteleostomi|Rep: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (Insulin-like growth factor I
receptor) (IGF-I receptor) (CD221 antigen) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain] - Homo
sapiens (Human)
Length = 1367
Score = 237 bits (581), Expect = 9e-61
Identities = 117/283 (41%), Positives = 173/283 (61%), Gaps = 10/283 (3%)
Query: 816 HRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY 875
HR RN + L + NP Y F + V +V+RE + + + LGQG+FG VY
Sbjct: 959 HRKRNNSRLGNGVLYASVNPEY----FSAADVYVPDEWEVAREKITMSRELGQGSFGMVY 1014
Query: 876 QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHP 935
+G+ + D E VA+KT+ E ++ + +FL EA++M +FN ++V L+GV P
Sbjct: 1015 EGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQP 1074
Query: 936 RFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKRFIHR 992
+++EL+ GDLK++LR RP+ E L ++ ++ + ++ G YL +F+HR
Sbjct: 1075 TLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHR 1134
Query: 993 DIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTT 1052
D+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DGVFTT
Sbjct: 1135 DLAARNCMVAE---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTT 1191
Query: 1053 KTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+DVWSFGV+LWE+ +L PY G +N +V+ V GG L+KP
Sbjct: 1192 YSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKP 1234
>UniRef50_Q9PVZ4 Cluster: Insulin receptor precursor (EC 2.7.10.1)
(IR) (Xe-InsR) (XTK-1b) [Contains: Insulin receptor
subunit alpha; Insulin receptor subunit beta]; n=6;
Euteleostomi|Rep: Insulin receptor precursor (EC
2.7.10.1) (IR) (Xe-InsR) (XTK-1b) [Contains: Insulin
receptor subunit alpha; Insulin receptor subunit beta] -
Xenopus laevis (African clawed frog)
Length = 1362
Score = 236 bits (577), Expect = 3e-60
Identities = 118/277 (42%), Positives = 172/277 (62%), Gaps = 14/277 (5%)
Query: 824 GNDNALAMAFNPHY--GSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRH 881
G L + NP Y SE ++P +V R+ + L++ LGQG+FG VY+G+ +
Sbjct: 980 GPAGPLYTSSNPEYLSASEVYIPDEWEV------PRDKINLLRELGQGSFGMVYEGIAKD 1033
Query: 882 RSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLE 941
E+ VAVKT+ E ++ + +FL EA++M FN ++V L+GV P +++E
Sbjct: 1034 IIKGEPEVRVAVKTVNESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIME 1093
Query: 942 LLAGGDLKNFLRESRPKPERAS---ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARN 998
L+A GDLK++LR RP E A T+K+++ + ++ G YL K+F+HRD+AARN
Sbjct: 1094 LMAHGDLKSYLRSLRPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARN 1153
Query: 999 CLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWS 1058
C++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DGVFT +DVWS
Sbjct: 1154 CMVAD---DYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWS 1210
Query: 1059 FGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
FGV+LWE+ SL PY G +N +V++ V GG L+ P
Sbjct: 1211 FGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDHP 1247
>UniRef50_Q25410 Cluster: Putative molluscan insulin-related
peptide(s) receptor precursor (EC 2.7.10.1) [Contains:
Putative molluscan insulin-related peptide(s) receptor
alpha chain; Putative molluscan insulin-related
peptide(s) receptor beta chain]; n=2; Coelomata|Rep:
Putative molluscan insulin-related peptide(s) receptor
precursor (EC 2.7.10.1) [Contains: Putative molluscan
insulin-related peptide(s) receptor alpha chain; Putative
molluscan insulin-related peptide(s) receptor beta chain]
- Lymnaea stagnalis (Great pond snail)
Length = 1607
Score = 235 bits (575), Expect = 5e-60
Identities = 110/245 (44%), Positives = 163/245 (66%), Gaps = 6/245 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
+V R+ +KL+K LGQG+FG VY+G+ + R E+PVAVKT+ + ++ +FL EA
Sbjct: 1031 EVDRDKIKLIKELGQGSFGMVYEGVAKGIRDDPNEEIPVAVKTVNDRASFSDRREFLKEA 1090
Query: 913 AIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALT--MKDL 970
M +F+ ++V L+GV P +++EL+A GDLKN+LR RP + + + D+
Sbjct: 1091 TTMKEFHCHHVVKLLGVVSTGQPALVIMELMALGDLKNYLRGHRPDEDHPGVMPPHLLDI 1150
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
L + ++ G YL K+F+HRD+AARNC+++ R VKI DFGM RDIY DYY+KG
Sbjct: 1151 LQMAGEIADGMAYLADKKFVHRDLAARNCMVSEE---RTVKIGDFGMTRDIYETDYYRKG 1207
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
GK MLP++WM PE+ DGVFT+ +DVWS+GV++WE+ +L PY G +N EV++ +S G
Sbjct: 1208 GKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTLAAQPYQGLSNEEVVKFISDGY 1267
Query: 1091 RLEKP 1095
+E P
Sbjct: 1268 IMELP 1272
>UniRef50_P14616 Cluster: Insulin receptor-related protein precursor
(EC 2.7.10.1) (IRR) (IR- related receptor) [Contains:
Insulin receptor-related protein alpha chain; Insulin
receptor-related protein beta chain]; n=14; Eutheria|Rep:
Insulin receptor-related protein precursor (EC 2.7.10.1)
(IRR) (IR- related receptor) [Contains: Insulin
receptor-related protein alpha chain; Insulin
receptor-related protein beta chain] - Homo sapiens
(Human)
Length = 1297
Score = 232 bits (567), Expect = 5e-59
Identities = 107/247 (43%), Positives = 160/247 (64%), Gaps = 6/247 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V RE + +++ LGQG+FG VY+GL R A PVA+KT+ EL++ + +FL EA+
Sbjct: 973 EVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEAS 1032
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDL 970
+M F ++V L+GV P +++EL+ GDLK+ LR RP+ E L + ++
Sbjct: 1033 VMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEM 1092
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
+ + ++ G YL +F+HRD+AARNC+++ VKI DFGM RD+Y DYY+KG
Sbjct: 1093 IQMAGEIADGMAYLAANKFVHRDLAARNCMVSQ---DFTVKIGDFGMTRDVYETDYYRKG 1149
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
GK +LP++WM PE+ DG+FTT +DVWSFGV+LWE+ +L PY G +N +V++ V GG
Sbjct: 1150 GKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGG 1209
Query: 1091 RLEKPYG 1097
LE+ G
Sbjct: 1210 VLEELEG 1216
>UniRef50_UPI0000D57494 Cluster: PREDICTED: similar to insulin
receptor; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to insulin receptor - Tribolium castaneum
Length = 1351
Score = 229 bits (560), Expect = 3e-58
Identities = 109/248 (43%), Positives = 164/248 (66%), Gaps = 10/248 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+ ++L++ LGQG+FG VY+G+ + A ++ AVKT+ E +T + +FL EA+
Sbjct: 974 EVPRKKIELIRELGQGSFGMVYEGIAQDVRGKA-QIKCAVKTVNEHATNRERLEFLNEAS 1032
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE---RASAL---TM 967
+M F+ A++V L+GV P +++EL+A GDLK +LR RP E A+A T+
Sbjct: 1033 VMKAFDTAHVVRLLGVVSQGQPTLVIMELMANGDLKTYLRSHRPDAEVYDPATAKQPPTL 1092
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
K +L ++++ G YL K+F+HRD+AARNC++ VKI DFGM RDIY DYY
Sbjct: 1093 KQILQMAIEIADGMAYLSAKKFVHRDLAARNCMVAE---DLTVKIGDFGMTRDIYETDYY 1149
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
+KG K +LP++WM PE+ DGVFT+ +DVWS+GV+LWE+ +L PY G +N +V+ V
Sbjct: 1150 RKGTKGLLPVRWMAPESLKDGVFTSNSDVWSYGVVLWEMATLASQPYQGLSNDQVLRYVI 1209
Query: 1088 GGGRLEKP 1095
GG +E+P
Sbjct: 1210 DGGVMERP 1217
>UniRef50_Q7YT64 Cluster: Tyrosine-protein kinase receptor; n=1;
Crassostrea gigas|Rep: Tyrosine-protein kinase receptor -
Crassostrea gigas (Pacific oyster) (Crassostrea angulata)
Length = 804
Score = 229 bits (560), Expect = 3e-58
Identities = 112/255 (43%), Positives = 162/255 (63%), Gaps = 16/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+ ++L++ LGQG+FG VY+G+ R E+ VAVKT+ E +T + +FL EA+
Sbjct: 329 EVERDKIQLIRELGQGSFGMVYEGVARDLYGKGGEIKVAVKTVNEHATYRERMEFLSEAS 388
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL-------- 965
M F+ ++V L+GV D P +++EL+ GDLKNFLR RP E +
Sbjct: 389 RMKAFSCNHVVRLLGVVSDGQPALLIMELMEKGDLKNFLRMHRPVEEDIDSTFAGIKEHI 448
Query: 966 -----TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
T+K ++ + ++ G YL K+F+HRD+AARNC++ VKIADFGM RD
Sbjct: 449 SRTPPTIKRIIQMAGEIADGMAYLADKKFVHRDLAARNCMVAE---DLTVKIADFGMTRD 505
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
IY DYY+KGGKA+LP++WM PE+ DG+FT+ +DVWS+GV+LWE+ +L PY G +N
Sbjct: 506 IYETDYYRKGGKALLPVRWMAPESLKDGIFTSLSDVWSYGVVLWEMATLAAQPYQGLSNE 565
Query: 1081 EVMELVSGGGRLEKP 1095
EV+ V G +EKP
Sbjct: 566 EVLRYVLNGRVMEKP 580
>UniRef50_Q25197 Cluster: Putative insulin-like peptide receptor
precursor; n=8; Eumetazoa|Rep: Putative insulin-like
peptide receptor precursor - Hydra attenuata (Hydra)
(Hydra vulgaris)
Length = 1477
Score = 225 bits (550), Expect = 5e-57
Identities = 110/249 (44%), Positives = 161/249 (64%), Gaps = 7/249 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++RE ++L++ LGQG+FG V++G+ H D AE+ VAVKT E ++ L EA+
Sbjct: 1038 ELNREKIELIRELGQGSFGMVFEGI-AHGIGDHAELRVAVKTTNENASIHDRIQILQEAS 1096
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM FN ++V LIGV P F+V+EL+ GDLK++L+E RP + L +++
Sbjct: 1097 IMKAFNCNHVVKLIGVVSQGQPTFVVMELMGRGDLKSYLKERRPD-DGGIPLMRQEIYQM 1155
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
++ G YL ++F+H D+AARNC++ S VKI DFGMARDIY +YY+K GK+
Sbjct: 1156 VAEIADGMAYLAARKFVHCDLAARNCMVAS---DFTVKIGDFGMARDIYERNYYRKDGKS 1212
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+LPI+WM PE+ DG+F+T +DVWSFGV+LWE+ +L PY G N +V+ V G L+
Sbjct: 1213 LLPIRWMAPESLKDGIFSTASDVWSFGVVLWEICTLASQPYQGKTNEQVLNFVLSNGHLD 1272
Query: 1094 KPYGEGSEY 1102
Y EG +Y
Sbjct: 1273 --YPEGCDY 1279
>UniRef50_UPI00015B5959 Cluster: PREDICTED: similar to insulin
receptor; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to insulin receptor - Nasonia vitripennis
Length = 1714
Score = 225 bits (549), Expect = 7e-57
Identities = 115/281 (40%), Positives = 169/281 (60%), Gaps = 15/281 (5%)
Query: 818 LRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQG 877
+RN P L NP Y S ++P +V R+ + L+K LG G+FG VY+G
Sbjct: 1096 MRNVPSMR---LIATVNPEYVSTVYIPDEWEV------PRKKVHLLKELGNGSFGMVYEG 1146
Query: 878 LYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRF 937
+ + EM AVKT+ E +T + +FL EA++M FN ++V L+GV P
Sbjct: 1147 IAKDVVKGKPEMRCAVKTVNENATDRERVEFLNEASVMKGFNTHHVVRLLGVVSQGQPTL 1206
Query: 938 IVLELLAGGDLKNFLRESRPKP-ERASAL--TMKDLLLCSVDVCKGCRYLETKRFIHRDI 994
+V+EL+ GDLK +LR RP E S T+ ++ ++++ G YL K+F+HRD+
Sbjct: 1207 VVMELMVNGDLKTYLRSHRPDVCENFSRQPPTLNRIMRMALEIADGMAYLAAKKFVHRDL 1266
Query: 995 AARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKT 1054
AARNC+++ VKI DFGM RD+Y DYY+KG K +LP++WM PE+ DGVFT+ +
Sbjct: 1267 AARNCMVSD---DLTVKIGDFGMTRDVYETDYYRKGTKGLLPVRWMAPESLKDGVFTSFS 1323
Query: 1055 DVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
DVWS+GV+LWE+ +L PY G +N +V+ V GG +E+P
Sbjct: 1324 DVWSYGVVLWEMVTLASQPYQGLSNDQVLRYVIDGGVMERP 1364
>UniRef50_UPI0000DB6DD4 Cluster: PREDICTED: similar to Insulin-like
growth factor 1 receptor precursor (Insulin-like growth
factor I receptor) (IGF-I receptor); n=1; Apis
mellifera|Rep: PREDICTED: similar to Insulin-like growth
factor 1 receptor precursor (Insulin-like growth factor I
receptor) (IGF-I receptor) - Apis mellifera
Length = 855
Score = 223 bits (544), Expect = 3e-56
Identities = 112/293 (38%), Positives = 177/293 (60%), Gaps = 13/293 (4%)
Query: 818 LRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQG 877
LRN P + L NP Y S ++ +D +P RE ++++++LG G FG VY+G
Sbjct: 297 LRNVP---NVTLIATVNPEYVSTPYV---LDEWEVP---REKIEMLRSLGTGTFGMVYEG 347
Query: 878 LYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRF 937
+ + +E+ AVKT+ + +T + +FL EA++M F+ ++V L+GV P
Sbjct: 348 IAKDIVKGKSEVRCAVKTVNKDATDRERIEFLNEASVMKGFDAHHVVKLLGVVTRGQPTL 407
Query: 938 IVLELLAGGDLKNFLRESRPKPERASALTMKDLLL-CSVDVCKGCRYLETKRFIHRDIAA 996
+++EL+ GDLK +LR RP ++A D +L ++++ G YL TK+F+HRD+AA
Sbjct: 408 VIMELMVNGDLKRYLRSHRPCENMSNAPPKLDRILQMAIEIADGMAYLSTKKFVHRDLAA 467
Query: 997 RNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDV 1056
RNC++ VK+ DFGM RDIY DYY+KG K +LP++WM PE+ DGVF++ +DV
Sbjct: 468 RNCMVAE---DLTVKVGDFGMTRDIYERDYYRKGSKGLLPVRWMAPESLKDGVFSSYSDV 524
Query: 1057 WSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKPYGEGSEYHKFKRRT 1109
WS+GV+LWE+ + PY G +N +V+ V GG +E+P ++ +RT
Sbjct: 525 WSYGVVLWEMVTFASQPYQGLSNEQVLRYVIEGGVMERPENCPELLYELMKRT 577
>UniRef50_Q93105 Cluster: Insulin-like receptor precursor (EC
2.7.10.1) (MIR) [Contains: Insulin-like receptor alpha
chain; Insulin-like receptor beta chain]; n=2; Aedes
aegypti|Rep: Insulin-like receptor precursor (EC
2.7.10.1) (MIR) [Contains: Insulin-like receptor alpha
chain; Insulin-like receptor beta chain] - Aedes aegypti
(Yellowfever mosquito)
Length = 1390
Score = 222 bits (543), Expect = 4e-56
Identities = 101/259 (38%), Positives = 160/259 (61%), Gaps = 7/259 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R + ++ LGQG+FG VY+G+ + P A+KT+ E +T + + FL+EA+
Sbjct: 1019 EVERNHIIQLEELGQGSFGMVYKGILTQLRGEKCNQPCAIKTVNESATAREKDSFLLEAS 1078
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL----TMKD 969
+M +FN ++V L+GV P +++EL+A GDLK++LR RP E ++ T++
Sbjct: 1079 VMKQFNTHHVVRLLGVVSQGDPTLVIMELMANGDLKSYLRRHRPDYEMRRSIRQPPTLRQ 1138
Query: 970 LLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKK 1029
++ ++++ G L K+F+HRD+AARNC++ VKI DFGM RDIY DYY+K
Sbjct: 1139 IIQMAIEIADGIGVLSAKKFVHRDLAARNCMVAD---DMTVKIGDFGMTRDIYETDYYRK 1195
Query: 1030 GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGG 1089
G K LP++WM PE+ DG+F++ +DV+S+GV+LWE+ +L PY G N +V+ V G
Sbjct: 1196 GTKGFLPVRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDG 1255
Query: 1090 GRLEKPYGEGSEYHKFKRR 1108
G +E+P + RR
Sbjct: 1256 GVMERPENCPDNLYNLMRR 1274
>UniRef50_P09208 Cluster: Insulin-like receptor precursor (EC
2.7.10.1) (DIR) (DInr) (dIRH) [Contains: Insulin-like
receptor subunit alpha; Insulin-like receptor subunit
beta 1; Insulin-like receptor subunit beta 2]; n=15;
Eumetazoa|Rep: Insulin-like receptor precursor (EC
2.7.10.1) (DIR) (DInr) (dIRH) [Contains: Insulin-like
receptor subunit alpha; Insulin-like receptor subunit
beta 1; Insulin-like receptor subunit beta 2] -
Drosophila melanogaster (Fruit fly)
Length = 2144
Score = 222 bits (542), Expect = 5e-56
Identities = 115/309 (37%), Positives = 180/309 (58%), Gaps = 26/309 (8%)
Query: 815 LHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEV 874
LH+ R P ND + NP Y S ++P +V RE++ + LGQG+FG V
Sbjct: 1334 LHK-RKVPS-NDLHMNTEVNPFYASMQYIPDDWEVL------RENIIQLAPLGQGSFGMV 1385
Query: 875 YQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRH 934
Y+G+ + + + A+KT+ E +T + ++FL EA++M +F+ ++V L+GVC
Sbjct: 1386 YEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQ 1445
Query: 935 PRFIVLELLAGGDLKNFLRESRPKPERASALTMKD---------------LLLCSVDVCK 979
P +V+EL+ GDLK++LR RP+ + +T + + ++++
Sbjct: 1446 PALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIAD 1505
Query: 980 GCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKW 1039
G YL K+F+HRD+AARNC++ VKI DFGM RDIY DYY+KG K +LP++W
Sbjct: 1506 GMAYLAAKKFVHRDLAARNCMVAD---DLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRW 1562
Query: 1040 MPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKPYGEG 1099
MPPE+ DGV+++ +DV+SFGV+LWE+ +L PY G +N +V+ V GG +E+P
Sbjct: 1563 MPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCP 1622
Query: 1100 SEYHKFKRR 1108
HK +R
Sbjct: 1623 DFLHKLMQR 1631
>UniRef50_Q9U5A8 Cluster: Insulin receptor-like protein precursor;
n=1; Bombyx mori|Rep: Insulin receptor-like protein
precursor - Bombyx mori (Silk moth)
Length = 1472
Score = 220 bits (538), Expect = 1e-55
Identities = 100/248 (40%), Positives = 159/248 (64%), Gaps = 9/248 (3%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V+R+S+ ++ LGQG+FG VY+G+ + E A+KT+ E +T + +FL EA+
Sbjct: 1076 EVTRDSIHFIRELGQGSFGMVYEGIAKEIVKGKPETRCAIKTVNEHATDRERIEFLNEAS 1135
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL------TM 967
+M F+ ++V L+GV P +V+EL+ GDLK +LR RP E + T+
Sbjct: 1136 VMKAFDTFHVVRLLGVVSRGQPTLVVMELMERGDLKTYLRSMRPDAEGSLPSSPPVPPTL 1195
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+++L ++++ G YL K+F+HRD+AARNC++ VK+ DFGM RDIY DYY
Sbjct: 1196 QNILQMAIEIADGMAYLSAKKFVHRDLAARNCMVAG---DLTVKVGDFGMTRDIYETDYY 1252
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
+KG K ++P++WM PE+ DGVF++ +D WS+GV+LWE+ +L + PY G +N +V+ V
Sbjct: 1253 RKGTKGLMPVRWMSPESLKDGVFSSSSDAWSYGVVLWEMATLAMQPYQGLSNEQVLRYVV 1312
Query: 1088 GGGRLEKP 1095
GG +E+P
Sbjct: 1313 EGGVMERP 1320
>UniRef50_O02466 Cluster: Insulin-like peptide receptor precursor (EC
2.7.10.1) (ILP receptor) [Contains: Insulin-like peptide
receptor alpha chain; Insulin-like peptide receptor beta
chain]; n=4; Eukaryota|Rep: Insulin-like peptide receptor
precursor (EC 2.7.10.1) (ILP receptor) [Contains:
Insulin-like peptide receptor alpha chain; Insulin-like
peptide receptor beta chain] - Branchiostoma lanceolatum
(Common lancelet) (Amphioxus)
Length = 1363
Score = 220 bits (537), Expect = 2e-55
Identities = 115/265 (43%), Positives = 163/265 (61%), Gaps = 24/265 (9%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V RE + L++ LGQG+FG VY+G + D + VAVKT+ E ++ + +FL EA+
Sbjct: 988 EVPREKITLIRELGQGSFGMVYEGEAKDVVKDEPMVSVAVKTVNESASIRERIEFLNEAS 1047
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP-------------- 959
+M FN ++V L+GV P +V+EL+A GDLKN+LR RP+
Sbjct: 1048 VMKTFNCHHVVKLMGVVSKGQPTLVVMELMALGDLKNYLRRHRPEEDVGLSDSPASNEAK 1107
Query: 960 -----ERASAL--TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKI 1012
E + L T KD++ + + G YL K+F+HRD+A RNC++ R VKI
Sbjct: 1108 NSPFAENDNDLPPTFKDIIQMAGVIADGMSYLAAKKFVHRDLACRNCMVAQ---DRTVKI 1164
Query: 1013 ADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVM 1072
DFGM RDIY DYY+KGGK +LP++WM PE+ GVFT+++DVWS+GV+LWE+ +L
Sbjct: 1165 GDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKVGVFTSQSDVWSYGVVLWEMATLASQ 1224
Query: 1073 PYTGCANREVMELVSGGGRLEKPYG 1097
PY G +N EV++ V GG LEKP G
Sbjct: 1225 PYQGKSNEEVLKFVIDGGMLEKPEG 1249
>UniRef50_O97191 Cluster: Tyrosine-protein kinase receptor; n=1;
Geodia cydonium|Rep: Tyrosine-protein kinase receptor -
Geodia cydonium (Sponge)
Length = 570
Score = 219 bits (535), Expect = 3e-55
Identities = 107/250 (42%), Positives = 156/250 (62%), Gaps = 14/250 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ + L L ++LG+GAFG VY+G + D + VA+KTL ++S + +F+ E+ +
Sbjct: 264 LAEDQLILTESLGEGAFGRVYKGSMKTGDDDDRTVEVAIKTLKDISQQENIDNFVQESIL 323
Query: 915 MAKFNHANIVHLIGVCFD---RHPRFIVLELLAGGDLKNFLRESRPKPERAS------AL 965
M FNH N++ L+GVCFD RHP IVL +A GDL+++L R L
Sbjct: 324 MLGFNHPNVLELLGVCFDTTDRHP-LIVLPFMANGDLRSYLMSKRDPSVTTKFTHFPQGL 382
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+ L+ ++V +G YL F+HRD+AARNC+++ V++ADFG++RD+Y D
Sbjct: 383 DEERALVMCLEVARGMEYLSNSSFVHRDLAARNCMVSGE---LTVRVADFGLSRDVYSKD 439
Query: 1026 YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMEL 1085
YY+ G K MLP+KWM PE+ D +FT K+DVWSFGV+ WEVFSL V PY G N E+ +
Sbjct: 440 YYRMGTKTMLPVKWMAPESLADNIFTVKSDVWSFGVVCWEVFSL-VAPYPGIGNHEMSDY 498
Query: 1086 VSGGGRLEKP 1095
+ GG RL+ P
Sbjct: 499 IGGGRRLKIP 508
>UniRef50_Q4RM64 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 410
Score = 219 bits (534), Expect = 5e-55
Identities = 112/230 (48%), Positives = 154/230 (66%), Gaps = 9/230 (3%)
Query: 795 YQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQ 854
Y++K + + R+ E +L ++R++ D +NP+Y F + + L +
Sbjct: 4 YRRKNDFHAVRGRLHSPEYKLSKIRSSTIMTD------YNPNY---CFSGKTASLNDLKE 54
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
V R+++ L++ALG GAFGEVY+G + D M VA+KTLPE+ + Q E DFLMEA I
Sbjct: 55 VPRKNITLLRALGHGAFGEVYEGQLLGMNNDNKPMQVAIKTLPEICSEQDEMDFLMEALI 114
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M+KF+H NIV IGV + PRFI+LEL+ GGD+K+FLR++RP+ + S L+M++LL +
Sbjct: 115 MSKFSHENIVRCIGVSLNILPRFILLELMTGGDMKSFLRQNRPRAGQTSLLSMRELLQMA 174
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRA 1024
D+ GCRYLE FIHRDIAARNCLLT GP RV KI DFGMARDIYR+
Sbjct: 175 RDIAFGCRYLEENHFIHRDIAARNCLLTCPGPERVAKIGDFGMARDIYRS 224
Score = 123 bits (297), Expect = 2e-26
Identities = 49/73 (67%), Positives = 63/73 (86%)
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
RA YY+KGG+AMLP+KWMPPEA+++G+FT KTD WSFGVLLWE+FSLG MPY +N+EV
Sbjct: 260 RASYYRKGGRAMLPVKWMPPEAFMEGIFTCKTDTWSFGVLLWEIFSLGYMPYPCKSNQEV 319
Query: 1083 MELVSGGGRLEKP 1095
+E V+ GGR++ P
Sbjct: 320 LEFVTSGGRMDPP 332
>UniRef50_Q52V39 Cluster: Tyrosine-protein kinase receptor; n=2;
Branchiostoma floridae|Rep: Tyrosine-protein kinase
receptor - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 797
Score = 218 bits (533), Expect = 6e-55
Identities = 108/250 (43%), Positives = 146/250 (58%), Gaps = 10/250 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R+++ V LG+GAFG VY G D VAVKTL E+S A DF EA +
Sbjct: 505 IQRDTIHFVGELGEGAFGRVYLGKCEKLKPDEDASLVAVKTLKEMSVEDARKDFDREAEL 564
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPERASALTM 967
+ H NIV GVC + P ++ E + GDL N+LR P P L++
Sbjct: 565 LTNMQHENIVKFYGVCTEGEPWLMIFEYMENGDLNNYLRSHGPDAAFLIKNPATHKELSI 624
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+LL SV V G Y+ ++ F+HRD+A RNCL+ G VVKI DFGM+RDIY DYY
Sbjct: 625 VELLQISVQVASGVEYMASQHFVHRDLATRNCLV---GDKLVVKIGDFGMSRDIYSTDYY 681
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
+ GG MLP++WMPPE+ + FT ++D+WSFGV+LWE+F+ G P+ AN EV+E ++
Sbjct: 682 RVGGHTMLPVRWMPPESVLYRKFTIESDIWSFGVVLWEIFTFGKQPWYELANHEVIECIT 741
Query: 1088 GGGRLEKPYG 1097
G L P G
Sbjct: 742 SGRLLGCPRG 751
>UniRef50_Q2LC18 Cluster: Tyrosine-protein kinase receptor; n=2;
Strongylocentrotus purpuratus|Rep: Tyrosine-protein
kinase receptor - Strongylocentrotus purpuratus (Purple
sea urchin)
Length = 1072
Score = 218 bits (532), Expect = 8e-55
Identities = 108/273 (39%), Positives = 171/273 (62%), Gaps = 10/273 (3%)
Query: 826 DNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSAD 885
D L + NP Y S S + V + R+ L++++ LG+G+FG VY+GL + +
Sbjct: 669 DGVLYASVNPEYMSTS----DMYVADEWEFPRDKLEIIRELGKGSFGMVYEGLAKGILPE 724
Query: 886 AAEMP-VAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLA 944
E+ VA+K++ ++ + +FL EA++M + N+V L+GV P ++++E +A
Sbjct: 725 EEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMA 784
Query: 945 GGDLKNFLRESRPKPER--ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLT 1002
GDLKN+LR RP+ ++ S T++ LL + ++ G +L ++++HRD++ARNCL++
Sbjct: 785 QGDLKNWLRARRPENQQDLPSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVS 844
Query: 1003 SRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVL 1062
G K+ADFG+ARDIY++DYY+K MLPI+WM PE+ DGVF +DVWSFG+L
Sbjct: 845 GEG---TCKVADFGLARDIYQSDYYRKERGGMLPIRWMAPESVKDGVFQASSDVWSFGIL 901
Query: 1063 LWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
LWE+ +LG +PY G +N E E + GG L P
Sbjct: 902 LWEMATLGELPYQGLSNEEAGEYIKGGNVLRPP 934
>UniRef50_Q7Q0F6 Cluster: Tyrosine-protein kinase receptor; n=2;
Cellia|Rep: Tyrosine-protein kinase receptor - Anopheles
gambiae str. PEST
Length = 1318
Score = 215 bits (524), Expect = 7e-54
Identities = 103/247 (41%), Positives = 154/247 (62%), Gaps = 9/247 (3%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V RE + ++ LGQG+FG VY+G+ D +P A+KT+ E +T + FL+EA
Sbjct: 987 EVPREHIIQLEELGQGSFGMVYKGIMTKLGNDV-NVPCAIKTVTENATERERDSFLIEAT 1045
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL-----TMK 968
IM +F+ ++V L GV P +++EL+A GDLK++LR RP E T+K
Sbjct: 1046 IMKEFHTHHVVRLYGVVSVGQPTLVIMELMANGDLKSYLRRHRPDYENGEESSPQPPTLK 1105
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+ ++++ G YL K+F+HRD+AARNC++ VKI DFGM RDIY DYY+
Sbjct: 1106 QIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVAE---DLTVKIGDFGMTRDIYETDYYR 1162
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
KG K LP++WM PE+ DG+F++ +DV+S+GV+LWE+ +L PY G N +V+ V
Sbjct: 1163 KGTKGFLPVRWMAPESLKDGMFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVID 1222
Query: 1089 GGRLEKP 1095
GG +E+P
Sbjct: 1223 GGVMERP 1229
>UniRef50_Q5IJ68 Cluster: Trk-like receptor tyrosine kinase; n=1;
Aplysia californica|Rep: Trk-like receptor tyrosine
kinase - Aplysia californica (California sea hare)
Length = 865
Score = 215 bits (524), Expect = 7e-54
Identities = 120/304 (39%), Positives = 173/304 (56%), Gaps = 13/304 (4%)
Query: 802 RQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVR--GLPQVSRES 859
RQ +K++ + + +RN G L N + F P G R + +V +
Sbjct: 237 RQVRKKLCSKRNGDNIVRNTDGAL--LLERMNNINKNPTYFSPSGASARRHAVQEVPADC 294
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN 919
L L++ +G+GAFG+V++G R A VAVK L + ++ A DF E IM+ F+
Sbjct: 295 LTLIEVVGEGAFGQVFRGELRSAEGGACHQ-VAVKVLKDGASPDAHEDFEREVEIMSAFD 353
Query: 920 HANIVHLIGVCFD--RHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK----DLLLC 973
H NI+ L+G+ ++V E + GDL LR + P A + T + DL+
Sbjct: 354 HDNILKLLGIVVQGVEGAPYMVFEYMEHGDLSELLRRNDPHLRSADSKTFRLNKSDLVEI 413
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGR--VVKIADFGMARDIYRADYYKKGG 1031
SV + G RYL +RF+HRD+A RNCL+ + PG +VKI+DFGM+RDIY DYYK GG
Sbjct: 414 SVQIATGMRYLAAQRFVHRDLATRNCLVGTAPPGAGLLVKISDFGMSRDIYTNDYYKIGG 473
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
MLPI+WM PEA G FT ++DVW++GV+LWE+FS G PY G +N EV+ + G
Sbjct: 474 SRMLPIRWMSPEAIKYGRFTCESDVWAYGVVLWEIFSYGRQPYFGHSNEEVIHFLDQGIL 533
Query: 1092 LEKP 1095
L++P
Sbjct: 534 LQRP 537
>UniRef50_UPI0000D55DFF Cluster: PREDICTED: similar to Insulin-like
growth factor 1 receptor precursor (Insulin-like growth
factor I receptor) (IGF-I receptor) (CD221 antigen); n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Insulin-like growth factor 1 receptor precursor
(Insulin-like growth factor I receptor) (IGF-I receptor)
(CD221 antigen) - Tribolium castaneum
Length = 1277
Score = 214 bits (523), Expect = 1e-53
Identities = 99/243 (40%), Positives = 157/243 (64%), Gaps = 12/243 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R +++++ LG+G+FG VY+GL + R + P A+KT+ E S+ ++ +FL E +
Sbjct: 914 EIDRNDIEIIRELGKGSFGTVYEGLIKSR-----QYPCAIKTISEKSSISSKMEFLNEGS 968
Query: 914 IMAKFNHAN-IVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLL 972
+M F+ + ++ L+G+ F+++EL+ GDLK++LR R + LT ++
Sbjct: 969 VMKSFSETHHVIKLLGIVSRGDRPFVIMELMERGDLKSYLRRCRGPSQN---LTTNEIYR 1025
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK 1032
+ ++ G YL K+F+HRD+AARNC++ + R VKI DFGMARDIY DYY+KG
Sbjct: 1026 MASEIADGMAYLSVKKFVHRDLAARNCMVAA---DRTVKIGDFGMARDIYETDYYRKGTA 1082
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
+LPI+WM PE+ DGVFTT +DVWS+GV+LWE+ +L +PY G EV++ V+ G L
Sbjct: 1083 GLLPIRWMAPESLADGVFTTDSDVWSYGVVLWEMATLAELPYQGLGAEEVLQFVTSGRTL 1142
Query: 1093 EKP 1095
+ P
Sbjct: 1143 DMP 1145
>UniRef50_UPI0000D5603D Cluster: PREDICTED: similar to Insulin
receptor precursor (IR); n=1; Tribolium castaneum|Rep:
PREDICTED: similar to Insulin receptor precursor (IR) -
Tribolium castaneum
Length = 1293
Score = 209 bits (510), Expect = 4e-52
Identities = 109/268 (40%), Positives = 159/268 (59%), Gaps = 11/268 (4%)
Query: 836 HYGSESFL-PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVK 894
H+G + L P I ++ R S+ + + LG+GAFG VY G D + VAVK
Sbjct: 876 HFGIDLRLNPSQITDLDKWEIPRNSVVINRKLGEGAFGTVYGG--EANFPDKGWVAVAVK 933
Query: 895 TLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRE 954
TL S+ + + DFL EA +M +F+H NI+ L+GVC P + ++E + GDLK FL
Sbjct: 934 TLKVGSSTEEKLDFLSEAEVMKRFDHKNIIKLLGVCTKEEPIYTIMEFMLYGDLKTFLLA 993
Query: 955 SR-----PKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRV 1009
R E + ++ K L + ++DV +G YL +++HRD+A+RNCL+ ++ R+
Sbjct: 994 RRHLVNDKTIEESDEISSKKLTMMALDVARGLSYLAQLKYVHRDVASRNCLINAQ---RI 1050
Query: 1010 VKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL 1069
VK+ADFGM R ++ DYYK K MLP++WM PE+ GVFT +DVWS+GVLL+E+ +
Sbjct: 1051 VKLADFGMTRPMFENDYYKFTRKGMLPVRWMSPESLALGVFTPSSDVWSYGVLLYEIITF 1110
Query: 1070 GVMPYTGCANREVMELVSGGGRLEKPYG 1097
G PY G N EV+E V G + P G
Sbjct: 1111 GSFPYQGMTNGEVLEYVKNGHTVTIPQG 1138
>UniRef50_Q7Q5T3 Cluster: Tyrosine-protein kinase receptor; n=3;
Endopterygota|Rep: Tyrosine-protein kinase receptor -
Anopheles gambiae str. PEST
Length = 646
Score = 208 bits (507), Expect = 9e-52
Identities = 96/235 (40%), Positives = 153/235 (65%), Gaps = 7/235 (2%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
+PQ + + ++ V+ LG+GAFG+VY+G ++ + + VAVK L E ++ + ++DF E
Sbjct: 366 VPQYTLQDVRFVEELGEGAFGKVYKGELTQKNGE--RIFVAVKALKENASAKTQADFKRE 423
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLL 971
+++ H NIV ++GV P ++ E +A GDL FL + P +L+ L
Sbjct: 424 IELISDLKHDNIVCILGVVLKEEPLCMLFEYMAQGDLHEFLIAN--SPNEGKSLSQLQFL 481
Query: 972 LCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGG 1031
L + +C G YL + ++HRD+AARNCL+ G VKI+DFG++RDIY +DYY+
Sbjct: 482 LIAQQICDGMEYLASHHYVHRDLAARNCLV---GDNLTVKISDFGLSRDIYSSDYYRVQS 538
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
K++LP++WMP E+ + G FTT++DVWSFGV+LWE++S G+ PY G +N+EV+ +V
Sbjct: 539 KSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGLQPYYGYSNQEVINMV 593
>UniRef50_Q17JW1 Cluster: Tyrosine protein kinase; n=2; Culicidae|Rep:
Tyrosine protein kinase - Aedes aegypti (Yellowfever
mosquito)
Length = 722
Score = 204 bits (498), Expect = 1e-50
Identities = 108/267 (40%), Positives = 156/267 (58%), Gaps = 11/267 (4%)
Query: 837 YGSESFLPQGIDVRGLP--QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVK 894
+G + P I V L +V ++ + + + LG+GAFG VY G + D VAVK
Sbjct: 268 FGIDLLSPSSIPVNTLDKWEVPKDRVVINRRLGEGAFGTVYGG--EAQIGDEGWTAVAVK 325
Query: 895 TLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRE 954
TL ST + + DFL EA M +F+H NIV L+GVC P + ++E + GDLK +L
Sbjct: 326 TLKIGSTTEDKVDFLSEAEAMKRFDHNNIVKLLGVCLQTEPVYTIMEFMLYGDLKTYLLA 385
Query: 955 SR----PKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVV 1010
R K S ++ K L + ++DV + YL ++++HRD+A RNC++ ++ RVV
Sbjct: 386 RRHLVNSKQSEDSDISPKRLTMMALDVSRALSYLAEQKYVHRDLACRNCMVNAQ---RVV 442
Query: 1011 KIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLG 1070
K+ DFGMAR + DYY+ K MLP++WM PE+ G+FT +DVWS+GVLL+E+ S G
Sbjct: 443 KLGDFGMARPTFENDYYRFNRKGMLPVRWMAPESLALGIFTPASDVWSYGVLLYEIISFG 502
Query: 1071 VMPYTGCANREVMELVSGGGRLEKPYG 1097
PY G N +V+E V G L P G
Sbjct: 503 SFPYQGMTNNQVLEHVKEGNCLTIPTG 529
>UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2;
Eumetazoa|Rep: Tyrosine-protein kinase receptor - Aplysia
californica (California sea hare)
Length = 1145
Score = 202 bits (494), Expect = 3e-50
Identities = 98/239 (41%), Positives = 150/239 (62%), Gaps = 14/239 (5%)
Query: 859 SLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKF 918
+++ ++ LG+GAFG+VY+G +++ VA+KTL E + + ++DF E +M+
Sbjct: 570 NIRFLQELGEGAFGKVYKGELVGLYGESSVTTVAIKTLKENALPKVQNDFRREVDLMSDM 629
Query: 919 NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA-----------LTM 967
H NIV L+GVC + P ++ E +A GDL +L P + +A L
Sbjct: 630 RHPNIVCLLGVCMKQEPMCMLFEYMAQGDLHEYLLSHSPHSDVTAAEDDSGTGGGHILEY 689
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
++L S V G YL + F+HRD+AARN L+ G VKI+DFG++RD+Y +DYY
Sbjct: 690 SEMLHVSTQVAAGMEYLASHHFVHRDLAARNILVAD---GLTVKISDFGLSRDVYSSDYY 746
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
+ K++LP++WMPPEA + G FTT +DVW+FGV+LWEVFS G+ PY G +N+EV+E++
Sbjct: 747 RVQSKSLLPVRWMPPEAILYGKFTTDSDVWAFGVVLWEVFSYGLQPYYGFSNQEVIEMI 805
>UniRef50_Q24488 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror precursor; n=1; Drosophila melanogaster|Rep:
Tyrosine-protein kinase transmembrane receptor Ror
precursor - Drosophila melanogaster (Fruit fly)
Length = 685
Score = 202 bits (494), Expect = 3e-50
Identities = 102/282 (36%), Positives = 170/282 (60%), Gaps = 11/282 (3%)
Query: 814 QLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGE 873
QL+ ++A GN L+ H S L + + + + + ++ ++ LG+GAFG+
Sbjct: 368 QLNNAQDAGRGNLGNLS----DHVALNSKLIERNTLLRINHFTLQDVEFLEELGEGAFGK 423
Query: 874 VYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDR 933
VY+G + + + VA+K L E ++ + + DF E +++ H NIV ++GV ++
Sbjct: 424 VYKG--QLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNK 481
Query: 934 HPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRD 993
P ++ E +A GDL FL + P +L+ + L ++ + +G +YL ++HRD
Sbjct: 482 EPYCMLFEYMANGDLHEFLISN--SPTEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRD 539
Query: 994 IAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTK 1053
+AARNCL+ G VVKI+DFG++RDIY +DYY+ K++LP++WMP E+ + G FTT+
Sbjct: 540 LAARNCLVNE---GLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTTE 596
Query: 1054 TDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+DVWSFGV+LWE++S G+ PY G +N+EV+ L+ L P
Sbjct: 597 SDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAP 638
>UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 948
Score = 200 bits (487), Expect = 2e-49
Identities = 110/269 (40%), Positives = 158/269 (58%), Gaps = 14/269 (5%)
Query: 846 GIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE 905
G+D LP+V R+ ++ LGQG FG V + + VAVK L E ++ Q +
Sbjct: 603 GLDGTPLPEVDRDKVRYEGDLGQGHFGLVVKATALGVVPGRDQCIVAVKILKEGASLQTK 662
Query: 906 SDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL 965
+F EAA+M F+H NIV LIGVC ++ P ++ E + GDL NFLR + PK + +SA
Sbjct: 663 KEFFHEAALMHSFDHPNIVKLIGVCVEQEPLCMIFEFMQLGDLNNFLRHNSPKWQESSAS 722
Query: 966 TMK------DL-----LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIAD 1014
K D+ + S+D+ G YL +IHRD+A RNCL++ G R+ KI+D
Sbjct: 723 CAKYGGPKCDITTPIQVAMSLDITAGLAYLADNHYIHRDLATRNCLVS--GDLRI-KISD 779
Query: 1015 FGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPY 1074
FG+++DIY DY + +LPI+WMPPEA + FTT++DVWS GV+LWE+FS G+ PY
Sbjct: 780 FGLSQDIYSTDYCRLSQSELLPIRWMPPEAILFARFTTQSDVWSLGVVLWELFSYGIQPY 839
Query: 1075 TGCANREVMELVSGGGRLEKPYGEGSEYH 1103
+N +V+ V G + P G SE +
Sbjct: 840 YSMSNEQVIAHVRDGNVMNCPDGCPSEIY 868
>UniRef50_P04629 Cluster: High affinity nerve growth factor receptor
precursor; n=28; Eumetazoa|Rep: High affinity nerve
growth factor receptor precursor - Homo sapiens (Human)
Length = 796
Score = 199 bits (486), Expect = 3e-49
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 494 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES- 552
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 553 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 612
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 613 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 669
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 670 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 729
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 730 QLSNTEAIDCITQGRELERP 749
>UniRef50_Q8JG38 Cluster: Fibroblast growth factor receptor 2
precursor; n=11; Eumetazoa|Rep: Fibroblast growth factor
receptor 2 precursor - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 817
Score = 199 bits (486), Expect = 3e-49
Identities = 105/254 (41%), Positives = 152/254 (59%), Gaps = 15/254 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
+ SR+ L L K LG+G FG+V + L + + VAVK L + +T + SD + E
Sbjct: 471 EFSRDKLTLGKPLGEGCFGQVVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSE 530
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 531 MEMMKMIGRHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDIARVS 590
Query: 964 --ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD+
Sbjct: 591 DEPLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTE---SNVMKIADFGLARDV 647
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E
Sbjct: 648 HNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEE 707
Query: 1082 VMELVSGGGRLEKP 1095
+ +L+ G R++KP
Sbjct: 708 LFKLLKEGHRMDKP 721
>UniRef50_Q91987 Cluster: BDNF/NT-3 growth factors receptor precursor;
n=17; Euteleostomi|Rep: BDNF/NT-3 growth factors receptor
precursor - Gallus gallus (Chicken)
Length = 818
Score = 199 bits (485), Expect = 4e-49
Identities = 100/247 (40%), Positives = 147/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 529 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 587
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + R + LT
Sbjct: 588 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNRPAELTQS 647
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 648 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 704
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 705 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 764
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 765 GRVLQRP 771
>UniRef50_UPI0000DB7F8D Cluster: PREDICTED: similar to Cad96Ca
CG10244-PA; n=3; Endopterygota|Rep: PREDICTED: similar to
Cad96Ca CG10244-PA - Apis mellifera
Length = 657
Score = 198 bits (484), Expect = 5e-49
Identities = 99/241 (41%), Positives = 142/241 (58%), Gaps = 5/241 (2%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R LK+ LG+G FG+V++ + + VAVKTL E +T + D E +M
Sbjct: 356 RHRLKVFNILGEGCFGQVWKCEALDIDGKSGAIIVAVKTLKENATERERLDLAQELRVMK 415
Query: 917 KFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-ALTMKDLLLCS 974
+ H N+V L+G C +R P F++LE ++GG L++FLR SR + LT +DL
Sbjct: 416 NLDPHPNVVRLLGCCTEREPMFVILEYVSGGKLQSFLRASREERNHGGPGLTSRDLTGFV 475
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+ KG YL +K IHRD+AARN L+ R K+ADFG ARD+ Y++ +
Sbjct: 476 YQIAKGMEYLASKGIIHRDLAARNILIDEN---RACKVADFGFARDVAANQIYERKSEGR 532
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
LPI+WM PE+ D +F+ K+D+WSFGVL+WE+ +LG PY G A EVM + G RL++
Sbjct: 533 LPIRWMAPESLYDNIFSVKSDIWSFGVLIWEIVTLGSTPYPGLAAAEVMRRIKEGYRLDR 592
Query: 1095 P 1095
P
Sbjct: 593 P 593
>UniRef50_Q9GRH2 Cluster: Tyrosine-protein kinase receptor; n=1; Sycon
raphanus|Rep: Tyrosine-protein kinase receptor - Sycon
raphanus
Length = 616
Score = 198 bits (484), Expect = 5e-49
Identities = 100/253 (39%), Positives = 155/253 (61%), Gaps = 20/253 (7%)
Query: 858 ESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAK 917
+SL +++ +G+GAFG+VY+GL + + +M VA+KTL T + FL EA+IM K
Sbjct: 215 DSLTMIREVGEGAFGKVYEGLLA--TVEDGDMTVAIKTLSVCDTMGQRNAFLAEASIMKK 272
Query: 918 FNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL------------ 965
F+ ++ L+G+ + +V+E +A GDL+ ++R+ RP+ + S
Sbjct: 273 FDSPYVMRLMGLVSTENKPLVVMEFMAEGDLRGYVRKCRPQNRQFSINSIETNGSAASVY 332
Query: 966 ---TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
T + +L ++ + KG Y+ K F+HRD+AARNC+L+S +KI DFG RDIY
Sbjct: 333 GIPTAERFMLWALQLSKGMAYVHEKHFVHRDLAARNCMLSSN---LTLKIGDFGFTRDIY 389
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
+DYY+K GK LP++WM PEA DG++ ++DVWS+GV+LWE+ +LG PY G +N EV
Sbjct: 390 ESDYYRKTGKGALPVRWMGPEALRDGMYIPESDVWSYGVVLWEMATLGDQPYKGKSNEEV 449
Query: 1083 MELVSGGGRLEKP 1095
+ LV G + P
Sbjct: 450 ISLVIAGDHMPLP 462
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase FER;
n=109; root|Rep: Proto-oncogene tyrosine-protein kinase
FER - Homo sapiens (Human)
Length = 822
Score = 198 bits (484), Expect = 5e-49
Identities = 109/241 (45%), Positives = 148/241 (61%), Gaps = 16/241 (6%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+S E + L + LG+G FGEVY+G + +++ VAVKT E + + FL EA I
Sbjct: 558 LSHEDVILGELLGKGNFGEVYKGTLKDKTS------VAVKTCKEDLPQELKIKFLQEAKI 611
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC R P +I++EL++GGD FLR R K E L +K L+ S
Sbjct: 612 LKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLR--RKKDE----LKLKQLVKFS 665
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+D G YLE+K IHRD+AARNCL+ G V+KI+DFGM+R Y G
Sbjct: 666 LDAAAGMLYLESKNCIHRDLAARNCLV---GENNVLKISDFGMSRQ-EDGGVYSSSGLKQ 721
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+PIKW PEA G +++++DVWSFG+LLWE FSLGV PY G N++ E V G R+
Sbjct: 722 IPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSA 781
Query: 1095 P 1095
P
Sbjct: 782 P 782
>UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18;
Euteleostomi|Rep: Transmembrane receptor PTK7-2 - Homo
sapiens (Human)
Length = 1030
Score = 197 bits (480), Expect = 2e-48
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 753 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 811
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 812 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 871
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 872 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 927
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 928 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 987
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 988 QPEGCPSKLYRLMQR 1002
>UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precursor;
n=29; Tetrapoda|Rep: Tyrosine-protein kinase-like 7
precursor - Homo sapiens (Human)
Length = 1070
Score = 197 bits (480), Expect = 2e-48
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 793 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 851
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 852 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 911
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 912 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 967
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 968 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 1027
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 1028 QPEGCPSKLYRLMQR 1042
>UniRef50_Q16620 Cluster: BDNF/NT-3 growth factors receptor precursor;
n=73; Gnathostomata|Rep: BDNF/NT-3 growth factors
receptor precursor - Homo sapiens (Human)
Length = 822
Score = 196 bits (478), Expect = 3e-48
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 651
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 652 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 708
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 769 GRVLQRP 775
>UniRef50_Q3TJ05 Cluster: 14 days pregnant adult female placenta cDNA,
RIKEN full-length enriched library, clone:I530025O09
product:fibroblast growth factor receptor 1, full insert
sequence; n=18; Eumetazoa|Rep: 14 days pregnant adult
female placenta cDNA, RIKEN full-length enriched library,
clone:I530025O09 product:fibroblast growth factor
receptor 1, full insert sequence - Mus musculus (Mouse)
Length = 386
Score = 194 bits (474), Expect = 8e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 36 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 95
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 96 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 155
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 156 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNALVTE---DNVMKIADFGLARDI 212
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 213 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 272
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 273 LFKLLKEGHRMDKPSNCTNELYMMMR 298
>UniRef50_Q4H3B8 Cluster: Tyrosine-protein kinase receptor; n=1; Ciona
intestinalis|Rep: Tyrosine-protein kinase receptor -
Ciona intestinalis (Transparent sea squirt)
Length = 465
Score = 194 bits (474), Expect = 8e-48
Identities = 92/244 (37%), Positives = 146/244 (59%), Gaps = 5/244 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ E+++L+ +G G FG+VY+GL + + VAVKTL + +FL EA+
Sbjct: 93 EIPEENVELMDEIGHGHFGKVYEGLAKQVVKGQPKTKVAVKTLHGNESISKRMEFLKEAS 152
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE--RASALTMKDLL 971
+M FN ++V L+GV +++E +A GDLK +LR +RP E + +++ L
Sbjct: 153 VMKAFNSHHVVRLLGVVSMSKRPMVIMEFMAKGDLKTYLRSTRPDAEIRKGDPPSLQQKL 212
Query: 972 LCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGG 1031
++ G YL +++HRD+AARNCL+ VKI DFG+ RD+Y DYY+
Sbjct: 213 QMCGEIADGMSYLSETKYVHRDLAARNCLVHE---DLTVKIGDFGLTRDVYETDYYRIDS 269
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+ +LP++WM PE+ DGVF +++DVWSFG++LWE+ +L PY G + +V V GG
Sbjct: 270 RGILPVRWMAPESLKDGVFDSRSDVWSFGIVLWEIATLAEQPYQGQQHDQVTRFVIDGGY 329
Query: 1092 LEKP 1095
+E+P
Sbjct: 330 MEQP 333
>UniRef50_Q8IXC7 Cluster: Isoform of FGFR2; n=23; Euteleostomi|Rep:
Isoform of FGFR2 - Homo sapiens (Human)
Length = 709
Score = 194 bits (474), Expect = 8e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 366 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 423
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 424 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 483
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 484 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 540
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 541 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 600
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 601 FKLLKEGHRMDKPANCTNELYMMMR 625
>UniRef50_Q2VXS7 Cluster: Proto-oncogene c-fes variant 4; n=77;
Eutheria|Rep: Proto-oncogene c-fes variant 4 - Homo
sapiens (Human)
Length = 752
Score = 194 bits (474), Expect = 8e-48
Identities = 105/241 (43%), Positives = 143/241 (59%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ E L L + +G+G FGEV+ G R A VAVK+ E ++ FL EA I
Sbjct: 486 LNHEDLVLGEQIGRGNFGEVFSGRLR-----ADNTLVAVKSCRETLPPDLKAKFLQEARI 540
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC + P +IV+EL+ GGD FLR + L +K LL
Sbjct: 541 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE------GARLRVKTLLQMV 594
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
D G YLE+K IHRD+AARNCL+T + V+KI+DFGM+R+ Y GG
Sbjct: 595 GDAAAGMEYLESKCCIHRDLAARNCLVTEKN---VLKISDFGMSREEADGVYAASGGSRQ 651
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+P+KW PEA G +++++DVWSFG+LLWE FSLG PY +N++ E V GGRL
Sbjct: 652 VPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPC 711
Query: 1095 P 1095
P
Sbjct: 712 P 712
>UniRef50_P11362 Cluster: Basic fibroblast growth factor receptor 1
precursor; n=310; Euteleostomi|Rep: Basic fibroblast
growth factor receptor 1 precursor - Homo sapiens (Human)
Length = 822
Score = 194 bits (473), Expect = 1e-47
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 472 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 531
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 532 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 591
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 592 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 648
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 649 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 708
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 709 LFKLLKEGHRMDKPSNCTNELYMMMR 734
>UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whole
genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF14764, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 635
Score = 194 bits (472), Expect = 1e-47
Identities = 102/266 (38%), Positives = 157/266 (59%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + ++ A VAVK L +T + +D + E
Sbjct: 342 ELPRDRLTLGKPLGEGCFGQVVLAEAVGLDKNKPARVTKVAVKMLKADATEKDRADLISE 401
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP---------KPER 961
+M H NI++L+G C P ++++E + G+L+++LR RP +P
Sbjct: 402 MEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLRDYLRARRPAGLEYWSSSRPVS 461
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
+++ + +L+ + V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARD+
Sbjct: 462 LASMEIMELVSAAYQVARGMAYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDV 518
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 519 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 578
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R+EKP E + R
Sbjct: 579 LFKLLKEGHRMEKPPTSTQELYLMMR 604
>UniRef50_P22182 Cluster: Fibroblast growth factor receptor 1
precursor; n=33; Euteleostomi|Rep: Fibroblast growth
factor receptor 1 precursor - Xenopus laevis (African
clawed frog)
Length = 812
Score = 193 bits (471), Expect = 2e-47
Identities = 104/256 (40%), Positives = 152/256 (59%), Gaps = 19/256 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFL 909
+V+R+ L L K LG+G FG+V GL + + + VAVK L ++ + SD +
Sbjct: 466 EVARDRLILGKPLGEGCFGQVVMAEAIGLDKEKPNKVTK--VAVKMLKSDASEKDLSDLI 523
Query: 910 MEAAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERA------ 962
E +M H NI++L+G C P ++++E + G+L+ +LR RP
Sbjct: 524 SEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYTSKGNLREYLRARRPPAMEYCYNPTC 583
Query: 963 ---SALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T ++KIADFG+AR
Sbjct: 584 VPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRDLAARNVLVTE---DNIMKIADFGLAR 640
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
DI+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 641 DIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPM 700
Query: 1080 REVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 701 EELFKLLKEGHRMDKP 716
>UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=18; Gnathostomata|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Gallus gallus (Chicken)
Length = 947
Score = 193 bits (470), Expect = 3e-47
Identities = 103/254 (40%), Positives = 148/254 (58%), Gaps = 18/254 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 652 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 711
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE--------RASALTMK 968
+F++ NIV L+GVC P ++ E +A GDL +LR+ P+ A A +
Sbjct: 712 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEYLRDRSPRNLCSLVQGGLEARACLLN 771
Query: 969 DLLLCSVD-------VCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L LC V G YL ++F+HRD+A RNCL+ G VVKIADFG++R++
Sbjct: 772 PLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGLSRNM 828
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
Y ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G A+ E
Sbjct: 829 YSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGMQPYYGMAHEE 888
Query: 1082 VMELVSGGGRLEKP 1095
V+ V G L P
Sbjct: 889 VIYYVRDGNILSCP 902
>UniRef50_UPI0000DB6B52 Cluster: PREDICTED: similar to Ror CG4926-PA;
n=3; Endopterygota|Rep: PREDICTED: similar to Ror
CG4926-PA - Apis mellifera
Length = 529
Score = 192 bits (468), Expect = 5e-47
Identities = 108/245 (44%), Positives = 148/245 (60%), Gaps = 18/245 (7%)
Query: 853 PQVS---RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFL 909
P+VS RESL ++ +G+G FG+VY+G D+ E+ VA+K L E + +AE DF+
Sbjct: 195 PEVSILQRESLAFLQEIGEGCFGKVYKG--ELCIGDSKEI-VAIKVLKETAPREAEEDFM 251
Query: 910 MEAAIMAKFNHANIVHLIGVCF--DRHPRFIVLELLAGGDLKNFLRESR------PKPER 961
E IM+ F H NI+ L G ++V E + GDL LR + PKPE
Sbjct: 252 REVDIMSTFGHRNILSLKGAVLREGNSSPWMVFEYMPYGDLAEVLRSNSRQFNRSPKPEM 311
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
LT + L ++ + G YL +RF+HRD+A RNCL+ G +VKIADFGM+RD+
Sbjct: 312 -QPLTEESLHWITIQIAAGMTYLSGQRFVHRDLACRNCLV---GYDFIVKIADFGMSRDV 367
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
Y DYYK G +LPI+WM PE+ + G FT ++DVWSFGV+LWEV+S G PY G N E
Sbjct: 368 YTCDYYKIKGSRLLPIRWMSPESVMYGRFTLESDVWSFGVVLWEVYSFGKQPYYGHNNEE 427
Query: 1082 VMELV 1086
V ++V
Sbjct: 428 VSKVV 432
>UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular
organisms|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 192 bits (468), Expect = 5e-47
Identities = 107/250 (42%), Positives = 148/250 (59%), Gaps = 16/250 (6%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ E +K+ + LG+GAFG+V++ + + VAVKT E FL EA I
Sbjct: 629 LKHEDIKMGRKLGKGAFGDVWEAALKGQGK------VAVKTCRSTDVPDREK-FLQEAEI 681
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGV +D P IV+EL+ GG L ++LR+ +A+ +T LL S
Sbjct: 682 LKQYDHPNIVKLIGVSWDTEPVLIVMELMPGGSLLDYLRK------KAAQMTKGKLLHMS 735
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+D C G YLE+K IHRD+AARNCL+ G +VKI+DFGM+R+ Y + G
Sbjct: 736 IDACGGMEYLESKNCIHRDLAARNCLV---GENDIVKISDFGMSREEEGGMYTVQSGTRQ 792
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+PIKW PEA G +T+ +DVWSFGVLL+EVFS G PY G +N E V G R+
Sbjct: 793 IPIKWTAPEALNYGRYTSASDVWSFGVLLYEVFSGGSTPYPGMSNAETRTQVDSGYRMPP 852
Query: 1095 PYGEGSEYHK 1104
P G +E H+
Sbjct: 853 PQGCPAEIHQ 862
>UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 4
SCAF14752, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 810
Score = 191 bits (466), Expect = 8e-47
Identities = 105/254 (41%), Positives = 149/254 (58%), Gaps = 15/254 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ E + L + LG+G FGEV++G + PVAVKT E + + FL EA I
Sbjct: 547 LNHEDVVLGELLGKGNFGEVFKGTLQRDKT-----PVAVKTCKEDLPSELKIRFLSEARI 601
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC R P +IV+EL+ GGD ++LR+ + + L K LL +
Sbjct: 602 LKQYDHPNIVKLIGVCTQRQPIYIVMELVPGGDFLSYLRKKKDE------LKTKQLLRFA 655
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
VD G YLE+K IHRD+AARNCL+ G +KI+DFGM+R Y G
Sbjct: 656 VDAAAGMAYLESKNCIHRDLAARNCLV---GDNNALKISDFGMSRQ-EDDGIYSSSGLKQ 711
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+PIKW PEA G +++++DVWS+G+LLWE FSLG+ PY G N++ E V G R+
Sbjct: 712 IPIKWTAPEALNYGRYSSESDVWSYGILLWETFSLGMCPYPGMTNQQAREQVEKGYRMAC 771
Query: 1095 PYGEGSEYHKFKRR 1108
P + +K +R
Sbjct: 772 PQRCPDDVYKVMQR 785
>UniRef50_Q9VBW3 Cluster: Tyrosine kinase receptor Cad96Ca precursor;
n=2; Diptera|Rep: Tyrosine kinase receptor Cad96Ca
precursor - Drosophila melanogaster (Fruit fly)
Length = 773
Score = 191 bits (466), Expect = 8e-47
Identities = 99/246 (40%), Positives = 142/246 (57%), Gaps = 10/246 (4%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R LK LG+GAFG+V++ + + + VAVKTL E +T D L E +M
Sbjct: 467 RYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMK 526
Query: 917 KFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE------RASALTMKD 969
H N+VHL+G C D+ P F++LE + G L+ +LR SR + +++ LT D
Sbjct: 527 SLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNVLTSCD 586
Query: 970 LLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKK 1029
L V KG YL ++ IHRD+AARN L+T K+ADFG ARD+ + Y++
Sbjct: 587 LTSFMYQVAKGMDYLTSRGIIHRDLAARNILITD---DHTCKVADFGFARDVITSKIYER 643
Query: 1030 GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGG 1089
+ LPI+WM E+ D +F+ K+D+WSFG+L+WE+ +LG PY G + +VM V G
Sbjct: 644 KSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDG 703
Query: 1090 GRLEKP 1095
RLEKP
Sbjct: 704 YRLEKP 709
>UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4 variant;
n=28; Eumetazoa|Rep: Fibroblast growth factor receptor 4
variant - Homo sapiens (Human)
Length = 1034
Score = 191 bits (465), Expect = 1e-46
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 696 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 753
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 754 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 813
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 814 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 870
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 871 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 930
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 931 FSLLREGHRMDRP 943
>UniRef50_A3EXK5 Cluster: Fibroblast growth factor receptor b; n=1;
Nematostella vectensis|Rep: Fibroblast growth factor
receptor b - Nematostella vectensis
Length = 591
Score = 190 bits (464), Expect = 1e-46
Identities = 102/251 (40%), Positives = 148/251 (58%), Gaps = 12/251 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + L+ LG+GAFG V + VAVK L E +T +D + E
Sbjct: 268 ELDRSQISLLGILGEGAFGRVVKADAIGLPNMPYRCNVAVKMLXEDATEHELADLVSEME 327
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALT------ 966
+M H NI++LIG C + P F+V+E + G+L+ FLR RP PE A+ LT
Sbjct: 328 VMKTIGQHVNIINLIGACTQKGPLFVVVEYASQGNLRQFLRARRPIPEYANPLTEPPREK 387
Query: 967 --MKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRA 1024
+ DL+ S V +G YLE+K+ IHRD+AARN L++ V+KIADFG+ARDI+
Sbjct: 388 LKLVDLVSFSYQVARGMEYLESKKCIHRDLAARNVLVSDN---HVIKIADFGLARDIHDI 444
Query: 1025 DYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVME 1084
DYY+K LP+KWM EA D V+T ++DVW++G+L+WE+ + G PY G ++ E
Sbjct: 445 DYYRKTTDGRLPVKWMALEALFDRVYTAQSDVWAYGILMWEIVTFGGSPYPGIPLWKLFE 504
Query: 1085 LVSGGGRLEKP 1095
L+ G R+E+P
Sbjct: 505 LLKEGYRMEQP 515
>UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=53; Euteleostomi|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Homo sapiens (Human)
Length = 869
Score = 190 bits (464), Expect = 1e-46
Identities = 105/258 (40%), Positives = 149/258 (57%), Gaps = 24/258 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 572 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 631
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL------ 970
+F++ NIV L+GVC P ++ E +A GDL FLR P +L+ DL
Sbjct: 632 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM--SPHTVCSLSHSDLSMRAQV 689
Query: 971 -------LLCSVDVC------KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
L C+ +C G YL ++F+HRD+A RNCL+ G VVKIADFG+
Sbjct: 690 SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGL 746
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
+R+IY ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G
Sbjct: 747 SRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM 806
Query: 1078 ANREVMELVSGGGRLEKP 1095
A+ EV+ V G L P
Sbjct: 807 AHEEVIYYVRDGNILSCP 824
>UniRef50_UPI0000E47068 Cluster: PREDICTED: similar to tyrosine
protein kinase; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to tyrosine protein kinase -
Strongylocentrotus purpuratus
Length = 1566
Score = 190 bits (462), Expect = 2e-46
Identities = 102/250 (40%), Positives = 146/250 (58%), Gaps = 11/250 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ RE++ L + LG+GAFG VY G D VAVKTL ++ + + DFL EA
Sbjct: 1014 EMPRENVVLNRKLGEGAFGTVYGG--EALLDDNKWAAVAVKTLKLGASVEEKLDFLSEAE 1071
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP-----ERASALTMK 968
+M +FNH NIV+L+GVC P + V+E + GDLK FL R ER +
Sbjct: 1072 VMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGRRHLVGEGVYERNQHVMCP 1131
Query: 969 DLLLCSV-DVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
D L V D+ G YL + ++HRD+A RNCL+ + VKI DFGM R +Y +DYY
Sbjct: 1132 DQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDA---SYTVKIGDFGMTRALYDSDYY 1188
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
+ G ++ LP++WM PE+ +G+FTT +DVWS GV+++EV + G PY +N EV++ +
Sbjct: 1189 RLGKRSKLPVRWMAPESLTEGIFTTMSDVWSLGVVIYEVVTFGSFPYQELSNAEVLDYIR 1248
Query: 1088 GGGRLEKPYG 1097
L P G
Sbjct: 1249 NRNSLRPPEG 1258
>UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase receptor;
n=5; Endopterygota|Rep: Muscle-specific tyrosine kinase
receptor - Aedes aegypti (Yellowfever mosquito)
Length = 666
Score = 190 bits (462), Expect = 2e-46
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 9/245 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R ++ +K LGQGAFG V+Q A VAVK L + ++ + DF EA ++A
Sbjct: 380 RNNIIYIKDLGQGAFGRVFQAKAPGLIAGEDFTLVAVKMLKDEASQDLQVDFEREACLLA 439
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP--KPERASALTMK----DL 970
+F+H NIV L+GVC P ++ E +A GDL FLR+ P + RA +T + DL
Sbjct: 440 EFDHPNIVKLLGVCAIGRPMCLLFEFMARGDLNEFLRQCSPFAQQNRADNITTELSHGDL 499
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
L + + G YL ++F+HRD+A RNCL+ VVKIADFG++ IY DYYK
Sbjct: 500 LSIASQIASGMVYLSERKFVHRDLATRNCLIDDN---MVVKIADFGLSHKIYLQDYYKGD 556
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
+PI+WMP E+ + +T ++DVW++GV LWE+FS + PY G + EV++ V G
Sbjct: 557 ENDAIPIRWMPLESILYNKYTIESDVWAYGVCLWEIFSFAMQPYYGMTHEEVVKFVKEGN 616
Query: 1091 RLEKP 1095
L P
Sbjct: 617 MLSCP 621
>UniRef50_O76997 Cluster: Putative neurotrophin receptor LTRK 1
precursor; n=2; Lymnaea stagnalis|Rep: Putative
neurotrophin receptor LTRK 1 precursor - Lymnaea
stagnalis (Great pond snail)
Length = 794
Score = 190 bits (462), Expect = 2e-46
Identities = 100/251 (39%), Positives = 142/251 (56%), Gaps = 13/251 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
V +++ L++ +G+GAFG V+ G H VAVKTL + + DF EA +
Sbjct: 499 VRLQTILLMRVIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEM 558
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP----ERASA------ 964
+A HANIV GVC + ++ E + GDL +LR P +R S
Sbjct: 559 LATIEHANIVTFYGVCTESDQWMMIFEFMENGDLNKYLRMHGPDAAFLKDRDSMDSDEGQ 618
Query: 965 LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRA 1024
LT + L+ + + YL + F+HRD+A RNCL+ G VVK+ DFGM+RD+Y
Sbjct: 619 LTREQLMKIVLQIASAMEYLALQHFVHRDLATRNCLV---GCDLVVKLGDFGMSRDVYTT 675
Query: 1025 DYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVME 1084
DYY+ G AMLP++WMPPE+ I FTT++DVWSFGV LWEVF+ G P+ +N EV+E
Sbjct: 676 DYYRVEGTAMLPVRWMPPESIIYRTFTTESDVWSFGVTLWEVFTYGKQPWFEYSNSEVIE 735
Query: 1085 LVSGGGRLEKP 1095
+ L++P
Sbjct: 736 HIKNSRTLKRP 746
>UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4
precursor; n=9; Eutheria|Rep: Fibroblast growth factor
receptor 4 precursor - Mus musculus (Mouse)
Length = 799
Score = 190 bits (462), Expect = 2e-46
Identities = 106/263 (40%), Positives = 154/263 (58%), Gaps = 15/263 (5%)
Query: 857 RESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
R+ L L K LG+G FG+V + S VAVK L + ++ + +D + E +
Sbjct: 461 RDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTSTVAVKMLKDNASDKDLADLVSEMEV 520
Query: 915 MAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA-- 964
M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 521 MKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGP 580
Query: 965 LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRA 1024
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 581 LSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDD---VMKIADFGLARGVHHI 637
Query: 1025 DYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVME 1084
DYYKK LP+KWM PEA D V+T ++DVWSF +LLWE+F+LG PY G E+
Sbjct: 638 DYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFTLGGSPYPGIPVEELFS 697
Query: 1085 LVSGGGRLEKPYGEGSEYHKFKR 1107
L+ G R+E+P SE + R
Sbjct: 698 LLREGHRMERPPNCPSELYGLMR 720
>UniRef50_UPI0000DB7735 Cluster: PREDICTED: similar to Insulin
receptor precursor (IR); n=1; Apis mellifera|Rep:
PREDICTED: similar to Insulin receptor precursor (IR) -
Apis mellifera
Length = 1374
Score = 188 bits (458), Expect = 7e-46
Identities = 98/249 (39%), Positives = 145/249 (58%), Gaps = 10/249 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + + LG+GAFG VY G + + VAVKTL S+ + + DFL E
Sbjct: 936 EIPRHRVVINRKLGEGAFGTVYGG--EAFFPEKGWLAVAVKTLKIGSSTEEKLDFLSEVE 993
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPERASALTMK 968
+M +F H NI+ L+GVC P V+E + GDLK +L R E + ++ K
Sbjct: 994 VMKQFEHKNIIKLLGVCIKSEPVLTVMEFMLYGDLKTYLLARRHLVNDNSYEDSDEISNK 1053
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L ++DV + YL +++HRDIA+RNCL+ ++ RVVK+ DFGM R +Y DYYK
Sbjct: 1054 KLTAMALDVARALSYLAQSKYVHRDIASRNCLVNAQ---RVVKLGDFGMTRLMYENDYYK 1110
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+ MLP++WM PE+ G+F+ +DVWS+GVLL+E+ + G P+ G +N EV+ V
Sbjct: 1111 FNRRGMLPVRWMAPESLGLGIFSPASDVWSYGVLLYEIITFGSFPFQGMSNIEVLNHVKS 1170
Query: 1089 GGRLEKPYG 1097
G L P G
Sbjct: 1171 GNSLMVPKG 1179
>UniRef50_UPI00004D7E5F Cluster: Proto-oncogene tyrosine-protein
kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor
tyrosine kinase MerTK).; n=1; Xenopus tropicalis|Rep:
Proto-oncogene tyrosine-protein kinase MER precursor (EC
2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK). -
Xenopus tropicalis
Length = 763
Score = 188 bits (458), Expect = 7e-46
Identities = 96/247 (38%), Positives = 146/247 (59%), Gaps = 12/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE-SDFLMEAA 913
V R L L K LG+G FG V +G ++ +D VAVKT+ + Q E +FL EAA
Sbjct: 466 VERNLLNLGKVLGEGEFGSVMEGELQY--SDGTNHKVAVKTMKMDNFSQREIEEFLSEAA 523
Query: 914 IMAKFNHANIVHLIGVCFDRHPR-----FIVLELLAGGDLKNFLRESRPKPERASALTMK 968
M FNH N++ L+GVC + PR ++L + GDL +FL SR + ++
Sbjct: 524 CMKDFNHPNVIRLLGVCLEVGPRRIPKPMVILPFMKYGDLHSFLLSSRIG-SGPQHVPLR 582
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+ +D+ G YL ++ F+HRD+AARNC+L V +ADFG+++ IY DYY+
Sbjct: 583 TLVKFMIDIATGMEYLSSRNFLHRDLAARNCMLRD---DMTVCVADFGLSKKIYSGDYYR 639
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+G A +P+KW+ E+ D ++T K+DVW+FGV +WE+ + G+ PY G N E+ + +
Sbjct: 640 QGRIAKMPVKWIAVESLADRIYTVKSDVWAFGVTMWEISTRGMTPYPGVQNHEIYDYLLV 699
Query: 1089 GGRLEKP 1095
G RL++P
Sbjct: 700 GHRLKQP 706
>UniRef50_Q7YXV8 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 865
Score = 188 bits (457), Expect = 1e-45
Identities = 100/238 (42%), Positives = 140/238 (58%), Gaps = 12/238 (5%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVH 925
+G+GAFG+VY+GL A+++ VA+KT+ + ++ F E A M F H NI+
Sbjct: 595 IGEGAFGKVYKGLLTQ--AESSVEHVAIKTIKIFAGIESIRSFFTECASMTSFRHPNIIE 652
Query: 926 LIGVCFDRHPR--FIVLELLAGGDLKNFLRESR-PKPERA----SALTMKDLLLCSVDVC 978
L G+CFD +VL + G+LK++L +SR P E+ + L + + D+
Sbjct: 653 LFGMCFDAPDGTPLMVLPFMINGNLKSYLVKSRNPLSEKPDIFPNELGLAVMTKMCTDIA 712
Query: 979 KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIK 1038
+G Y +RF+HRD+AARNCLL VKI DFG+AR++Y YYK +A LP+K
Sbjct: 713 RGMSYFVDQRFVHRDLAARNCLLDH---DLTVKIGDFGLARNVYMTGYYKASTRAALPVK 769
Query: 1039 WMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKPY 1096
WM PE DG+ KTDVW++GV WEVFSLG PY G N V+E + G RL KP+
Sbjct: 770 WMAPEMLRDGISNEKTDVWAYGVTCWEVFSLGSTPYPGVDNHLVLEHLMKGFRLAKPF 827
>UniRef50_P30530 Cluster: Tyrosine-protein kinase receptor UFO
precursor; n=37; Euteleostomi|Rep: Tyrosine-protein
kinase receptor UFO precursor - Homo sapiens (Human)
Length = 887
Score = 188 bits (457), Expect = 1e-45
Identities = 101/248 (40%), Positives = 145/248 (58%), Gaps = 14/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
V R + L K LG+G FG V +G + D + + VAVKT+ + T DFL EA
Sbjct: 524 VDRHKVALGKTLGEGEFGAVMEG---QLNQDDSILKVAVKTMKIAICTRSELEDFLSEAV 580
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H N++ LIGVCF R ++L + GDL +FL SR ++ L
Sbjct: 581 CMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSR-LGDQPVYLPT 639
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ D+ G YL TKRFIHRD+AARNC+L V +ADFG+++ IY DYY
Sbjct: 640 QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNEN---MSVCVADFGLSKKIYNGDYY 696
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G A +P+KW+ E+ D V+T+K+DVWSFGV +WE+ + G PY G N E+ + +
Sbjct: 697 RQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLR 756
Query: 1088 GGGRLEKP 1095
G RL++P
Sbjct: 757 QGNRLKQP 764
>UniRef50_Q86PM4 Cluster: Fibroblast growth factor receptor precursor;
n=1; Hydra vulgaris|Rep: Fibroblast growth factor
receptor precursor - Hydra attenuata (Hydra) (Hydra
vulgaris)
Length = 816
Score = 188 bits (457), Expect = 1e-45
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 8/247 (3%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ E L+ LG+GAFG V++ R VAVK L E Q DF+ E
Sbjct: 468 EIKLEQLETDCLLGEGAFGRVFRATARDLPNHTGVQTVAVKMLKEDCCEQDLKDFISEIE 527
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK---- 968
+M H NI++L+ V + +IV+E G+L++FL+++RP + S +T K
Sbjct: 528 VMKSIGKHINILNLLAVSSQQGKLYIVVEYCRHGNLRSFLKDNRPVMQANSVITKKITLY 587
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
DL + V +G +L +K+ IHRDIAARN L+ G G ++KIADFG+ARDI+ DYY+
Sbjct: 588 DLTSFCLQVARGMNFLASKKCIHRDIAARNVLV---GEGYLMKIADFGLARDIHEQDYYR 644
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K LP+KWM EA D V+TT++D+WSFG+L WE+ + G PY G A ++ +L+
Sbjct: 645 KCTDGRLPVKWMAIEALFDRVYTTQSDIWSFGILAWEIVTFGGSPYPGIALEKLFDLLKQ 704
Query: 1089 GGRLEKP 1095
G R+E+P
Sbjct: 705 GYRMERP 711
>UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; n=3;
Danio rerio|Rep: hypothetical protein LOC553690 - Danio
rerio
Length = 981
Score = 187 bits (455), Expect = 2e-45
Identities = 98/259 (37%), Positives = 156/259 (60%), Gaps = 11/259 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSA-DAAEMPVAVKTLPELSTGQAESDFLMEA 912
Q R +L + LG+G FGEV L + ++A D E V VK+L + Q + DF E
Sbjct: 702 QFPRSNLHTITTLGKGEFGEVL--LAKAKAAEDEEETVVLVKSL-QTRDEQMQMDFRREC 758
Query: 913 AIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDL 970
+ AK +H+N+ L+G+C + P ++++E GDLK +LR S+ K E+ L+ K
Sbjct: 759 DMFAKLSHSNVARLLGICREVEPHYMIMEYTDMGDLKQYLRVSKSKDEKVKVQPLSTKQK 818
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
+ + V +G +L +RF+H+D+AARNCL++S+ R +K++ G+++D+Y ++YY
Sbjct: 819 VSVCLQVARGMEHLSNQRFVHKDLAARNCLISSK---RQIKVSSLGLSKDVYSSEYYHYR 875
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
++ +P++W+P EA + F+TKTDVWSF VL+WEVFS G MPY A+ +V+E + G
Sbjct: 876 -QSYIPLRWLPSEAVFEDDFSTKTDVWSFAVLMWEVFSFGEMPYADLADDKVLEALQDGK 934
Query: 1091 -RLEKPYGEGSEYHKFKRR 1108
+L P G S K R
Sbjct: 935 LKLCPPQGCPSRVFKLMVR 953
>UniRef50_Q1JUB8 Cluster: Fibroblast growth factor receptor; n=2;
Obtectomera|Rep: Fibroblast growth factor receptor -
Bombyx mori (Silk moth)
Length = 856
Score = 187 bits (455), Expect = 2e-45
Identities = 109/267 (40%), Positives = 150/267 (56%), Gaps = 17/267 (6%)
Query: 839 SESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPE 898
SE LP ID +V RESL L K LG+G FG+V + + VAVK L E
Sbjct: 523 SEYELPMDIDW----EVPRESLSLGKVLGEGEFGKVVKAECIGILKPGLQSVVAVKMLKE 578
Query: 899 LSTGQAESDFLMEAAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP 957
T + E +M H NI++L+G C P ++++E G+L+ FLR RP
Sbjct: 579 GHTDAEMMALVSEMEMMKMIGKHVNIINLLGCCTQDGPLYVIVEYAPNGNLREFLRNHRP 638
Query: 958 -----KP----ERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGR 1008
P + LT KDL+ S V +G YL ++R IHRD AARN L++
Sbjct: 639 GNRYESPNEDLKEKKTLTQKDLVSFSYQVARGMEYLASRRCIHRDSAARNVLVSD---DC 695
Query: 1009 VVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFS 1068
V+KIADFG+A+D++ DYY+K + LP++WM PE+ VFTT+TDVWSFGVLLWE+ +
Sbjct: 696 VLKIADFGLAKDVHSNDYYRKKTEGRLPVRWMAPESLYHKVFTTQTDVWSFGVLLWEIMT 755
Query: 1069 LGVMPYTGCANREVMELVSGGGRLEKP 1095
LG PY + + + +S G R+EKP
Sbjct: 756 LGGTPYPTVPGQYMYQHLSAGHRMEKP 782
>UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6;
Endopterygota|Rep: Tyrosine-protein kinase Src64B -
Drosophila melanogaster (Fruit fly)
Length = 552
Score = 187 bits (455), Expect = 2e-45
Identities = 107/250 (42%), Positives = 149/250 (59%), Gaps = 17/250 (6%)
Query: 846 GIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE 905
G ++R ++ R ++L++ LG+G FGEV+ G +R+ + VAVKTL E + A
Sbjct: 270 GPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRN------SIDVAVKTLREGTMSTAA 323
Query: 906 SDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL 965
FL EAAIM KF H +V L VC P +IV E ++ G L +FLRE + L
Sbjct: 324 --FLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGR-----YL 376
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+DL+ + V G YLE+K+ IHRD+AARN L+ G V KI DFG+AR I +
Sbjct: 377 HFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLI---GENNVAKICDFGLARVIADDE 433
Query: 1026 YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMEL 1085
Y K G + P+KW PEA I G F+ K+DVWS+G+LL E+F+ G +PY G +REV+E
Sbjct: 434 YCPKQG-SRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIEN 492
Query: 1086 VSGGGRLEKP 1095
+ G R+ KP
Sbjct: 493 IERGFRMPKP 502
>UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020257 - Anopheles gambiae
str. PEST
Length = 1192
Score = 186 bits (454), Expect = 2e-45
Identities = 98/251 (39%), Positives = 145/251 (57%), Gaps = 15/251 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++S + + L+ +G+G FG+VY+ + + TLPE + + FL E
Sbjct: 925 ELSNDDVILLDKIGRGNFGDVYKAKLKSSKNTLVAVKTCRMTLPE----EQKRKFLQEGR 980
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I+ +++H NIV LIG+C + P IV+EL+AGG L FLR++ AS L + ++
Sbjct: 981 ILKQYDHPNIVKLIGICVQKQPIMIVMELVAGGSLLMFLRKN------ASTLGQRQMMGM 1034
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
D G RYLE+K IHRD+AARNCL+ G +VKI+DFGM+R+ +Y GG
Sbjct: 1035 CRDAAAGMRYLESKNCIHRDLAARNCLI---GSENIVKISDFGMSRE--EEEYIVSGGMK 1089
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+PIKW PEA G +T+ DVWS+G+L+WE+FS G PY+G +N E + G R+
Sbjct: 1090 QIPIKWTAPEALNFGKYTSLCDVWSYGILVWEIFSRGDTPYSGMSNSMARERIDEGYRMP 1149
Query: 1094 KPYGEGSEYHK 1104
P G E ++
Sbjct: 1150 APEGAPPEMYR 1160
>UniRef50_Q9Y1Y7 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 709
Score = 186 bits (452), Expect = 4e-45
Identities = 97/253 (38%), Positives = 149/253 (58%), Gaps = 15/253 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ + L+++ +GQG FG VY+ R + + VAVKT+ ++ S L E+
Sbjct: 380 IPEQCLQIMDCIGQGEFGIVYRAYLREWAKYPSPHLVAVKTIKGETSDSQISQMLEESVK 439
Query: 915 MAKFNHANIVHLIGVCFD-RHPRFIVLELLAGGDLKNFLRESRPKPERASAL-------T 966
M F+H NI+ LIGVC +IV+ +A G L ++L++ R A+ T
Sbjct: 440 MKDFDHPNILSLIGVCIAIESSPYIVMPFMANGSLLSYLKQQRHNLTIANGAEQDLITET 499
Query: 967 MKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADY 1026
+ LL + + KG YL +++F+HRD+AARNC++ V+K+ADFG++ D+Y +Y
Sbjct: 500 QRVLLSICLQIAKGMEYLASQKFVHRDLAARNCMIDLNN---VIKVADFGLSEDMYAKNY 556
Query: 1027 YKKGG----KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
Y++ K LPI+WM PE++ DGVF+ KTDVWS+GV WEVF+LG +PY G +
Sbjct: 557 YRQSDVEECKVKLPIRWMAPESFHDGVFSEKTDVWSYGVTCWEVFTLGKIPYPGVTPFTL 616
Query: 1083 MELVSGGGRLEKP 1095
++ + GGRLEKP
Sbjct: 617 IKYLDEGGRLEKP 629
>UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror2 precursor; n=2; Sophophora|Rep:
Tyrosine-protein kinase transmembrane receptor Ror2
precursor - Drosophila melanogaster (Fruit fly)
Length = 724
Score = 186 bits (452), Expect = 4e-45
Identities = 97/258 (37%), Positives = 142/258 (55%), Gaps = 9/258 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R + V++LGQGAFG V+Q D ++ VAVK L + ++ Q + DF EA ++A
Sbjct: 438 RGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLA 497
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA------LTMKDL 970
+F+H NIV L+GVC P ++ E +A GDL FLR P + L L
Sbjct: 498 EFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHL 557
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
L + ++ G YL ++F+HRD+A RNCL+ VKIADFG++ IY DYYK
Sbjct: 558 LQMAANIAAGMLYLSERKFVHRDLATRNCLINEH---MAVKIADFGLSHKIYLQDYYKGD 614
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
+PI+WMP E+ + F+ ++DVW++G+ LWEVFS + PY G + EV++ + G
Sbjct: 615 ENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGN 674
Query: 1091 RLEKPYGEGSEYHKFKRR 1108
L P + RR
Sbjct: 675 VLGCPDNTPLSVYALMRR 692
>UniRef50_UPI00015B51DA Cluster: PREDICTED: similar to
ENSANGP00000013218; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000013218 - Nasonia
vitripennis
Length = 972
Score = 184 bits (449), Expect = 9e-45
Identities = 98/258 (37%), Positives = 145/258 (56%), Gaps = 13/258 (5%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R L + + LG+G FG V + + + + VAVKTL E ++ +D L E ++
Sbjct: 498 RSRLSIEQVLGEGEFGRVLRAKAQDIAGWQGQTTVAVKTLKEDASASELADLLSEYQLLK 557
Query: 917 KFNHANIVHLIGVCFDRH-PRFIVLELLAGGDLKNFLR-------ESRPK--PERASALT 966
+ H N++ L+G C P ++++E G L+N+LR E RP P +T
Sbjct: 558 EAQHPNVIRLLGACTTAGGPIYLIIEFAEFGSLRNYLRRSRHLESEGRPSIDPVVNYTIT 617
Query: 967 MKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADY 1026
+D+L + + KG YL + +HRD+AARN LL G G+V KI+DFG+ RD+Y D
Sbjct: 618 PRDILSFAWQISKGMAYLADIKLVHRDLAARNVLL---GAGKVCKISDFGLTRDVYEDDA 674
Query: 1027 YKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
Y K K +P+KWM PE+ D V+T+K+DVWSFGVLLWE+ +LG PY G + L+
Sbjct: 675 YLKRSKGRVPVKWMAPESLADHVYTSKSDVWSFGVLLWELVTLGASPYPGVDVHNLYNLL 734
Query: 1087 SGGGRLEKPYGEGSEYHK 1104
G R+EKP + +K
Sbjct: 735 KAGYRMEKPANCSHQLYK 752
>UniRef50_Q9Y1Y5 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 557
Score = 184 bits (449), Expect = 9e-45
Identities = 93/238 (39%), Positives = 135/238 (56%), Gaps = 11/238 (4%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ G+G+F +VY+G E VAVK + + + F E ++M H N+
Sbjct: 290 EVFGEGSFSKVYRGTLHQMGTGTTE--VAVKAMKSIESDAEMKSFFTECSVMQTLKHPNV 347
Query: 924 VHLIGVCFDRHPRF--IVLELLAGGDLKNFLRESRPKPERASA----LTMKDLLLCSVDV 977
+ ++G+CFD +VL + G+LK++L++ R + L+++ L VD+
Sbjct: 348 LGILGMCFDSPDSIPLMVLPFMVNGNLKDYLKKHRGPHLQLETYPENLSLQMLKRICVDI 407
Query: 978 CKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPI 1037
+G YL +RF+HRD+AARNCLL S VK+ DFG+ RDIY +YY+ + LP+
Sbjct: 408 TRGMSYLADRRFVHRDLAARNCLLDS---ALAVKVGDFGLTRDIYLTNYYRAPTETKLPV 464
Query: 1038 KWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
KWMPPE DGV KTDVWSFGV WEVFS G PY G N +++ + G RL+KP
Sbjct: 465 KWMPPEMLQDGVSDEKTDVWSFGVTCWEVFSFGSTPYPGVDNHLMLQHLMSGLRLQKP 522
>UniRef50_Q26614 Cluster: Fibroblast growth factor receptor precursor;
n=4; Eumetazoa|Rep: Fibroblast growth factor receptor
precursor - Strongylocentrotus purpuratus (Purple sea
urchin)
Length = 972
Score = 184 bits (449), Expect = 9e-45
Identities = 101/257 (39%), Positives = 146/257 (56%), Gaps = 13/257 (5%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R+ L + K +G+GAFG+V G VAVK L + + SD + E A+M
Sbjct: 636 RDRLTVGKTIGEGAFGKVVIGEAVGIVCQEKTSTVAVKMLKANAMDREFSDLISELAMMK 695
Query: 917 KFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE--------RASALTM 967
+ NI++L+G C P ++++E G+L++FLR RP E + LT
Sbjct: 696 MIGKNPNIINLLGCCTQEGPPYVIVEFAHHGNLRDFLRSRRPPEEYEKSILLTTSQTLTN 755
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
KDL+ + V +G +L +K+ IHRD+AARN L+T +KI DFG+ARDI+ D+Y
Sbjct: 756 KDLMSMAYQVARGMDFLASKKCIHRDLAARNVLVTEDFE---MKICDFGLARDIHYIDFY 812
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
+K LP+KWM PEA D +FTT++DVWSFG+LLWE+ +LG PY ++ + +
Sbjct: 813 RKTTDGRLPVKWMAPEALFDRMFTTQSDVWSFGILLWEIMTLGGTPYPSVPVEQMFDYLR 872
Query: 1088 GGGRLEKPYGEGSE-YH 1103
G RLEKP E YH
Sbjct: 873 SGKRLEKPQNTSLEIYH 889
>UniRef50_Q9GRH1 Cluster: Tyrosine-protein kinase receptor; n=4;
Porifera|Rep: Tyrosine-protein kinase receptor - Sycon
raphanus
Length = 614
Score = 184 bits (448), Expect = 1e-44
Identities = 92/250 (36%), Positives = 152/250 (60%), Gaps = 17/250 (6%)
Query: 858 ESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAK 917
+SL +VK +G+GAFG+VY+G+ + + ++ VA+KTL + FL EA+IM K
Sbjct: 241 DSLTMVKEVGEGAFGKVYEGVLA--TIEDGDLTVAIKTLSTCENVAQRNAFLGEASIMKK 298
Query: 918 FNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPER------------ASAL 965
F+ ++ L G+ + +V+E +A GDL+ +L + RP+ E+ + A
Sbjct: 299 FDCPYVMRLFGLVSTVNKPLVVMEFMAEGDLRGYLMKCRPQEEQFATRFSGSSQSTSKAP 358
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
++ L ++ + KG ++ K F+HRD+AARNC++ + V+KI DFG RDIY +D
Sbjct: 359 SVDQFKLWALQLAKGMAHVHEKHFVHRDLAARNCMIATN---LVLKIGDFGFTRDIYESD 415
Query: 1026 YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMEL 1085
YY+K G +LP++WM PE DG++ ++DVWS+G++LWE+ +L G ++ EVM +
Sbjct: 416 YYRKTGGGVLPVRWMGPECLRDGLYIPESDVWSYGIVLWEMATLRGPAIPGESHEEVMNM 475
Query: 1086 VSGGGRLEKP 1095
V G G +E+P
Sbjct: 476 VIGSGHMERP 485
>UniRef50_Q5I4E2 Cluster: Bm-DAF-2 precursor; n=1; Brugia malayi|Rep:
Bm-DAF-2 precursor - Brugia malayi (Filarial nematode
worm)
Length = 1456
Score = 184 bits (448), Expect = 1e-44
Identities = 97/262 (37%), Positives = 151/262 (57%), Gaps = 10/262 (3%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEM--PVAVKTLPELSTGQAESDFLME 911
++ R ++ L +G+G FG+VY+G + + A+KT+ E + FL+E
Sbjct: 1038 ELKRSAIHLEDEIGRGTFGKVYRGYGDNCKSYLGVTFGECAIKTVSETANSAERLHFLIE 1097
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPER-ASALTMK-- 968
A++M +FN IV L GV D P +V+E++ G+L+++LR RP E + L +
Sbjct: 1098 ASVMKQFNTPFIVKLYGVVSDGQPVLVVMEMMKKGNLRDYLRSRRPNAEENVNGLPVPGA 1157
Query: 969 -DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
D + V G YLE+ +F HRD+AARNC++ VKI DFGMARDIY +YY
Sbjct: 1158 IDFFRWASQVADGMAYLESLKFCHRDLAARNCMVNEFD---TVKIGDFGMARDIYYHEYY 1214
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
K GK ++P++WM PE+ +DG FT K+DVWS+G+ L+E+ +L PY G AN V + +
Sbjct: 1215 KPAGKRLMPVRWMAPESLMDGKFTMKSDVWSYGITLYEMLTLAQQPYLGLANESVFDYIG 1274
Query: 1088 GGGR-LEKPYGEGSEYHKFKRR 1108
+ L +P G +++ +R
Sbjct: 1275 VKKKILTRPTGCPDFWYELMKR 1296
>UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane
receptor ROR1 precursor; n=21; Euteleostomi|Rep:
Tyrosine-protein kinase transmembrane receptor ROR1
precursor - Homo sapiens (Human)
Length = 937
Score = 184 bits (448), Expect = 1e-44
Identities = 94/238 (39%), Positives = 148/238 (62%), Gaps = 14/238 (5%)
Query: 859 SLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKF 918
+++ ++ LG+ AFG++Y+G D A++ VA+KTL + + Q ++F EA++MA+
Sbjct: 472 AVRFMEELGECAFGKIYKGHLYLPGMDHAQL-VAIKTLKDYNNPQQWTEFQQEASLMAEL 530
Query: 919 NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERA----------SALTMK 968
+H NIV L+G P ++ E + GDL FL P + S+L
Sbjct: 531 HHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHG 590
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
D L ++ + G YL + F+H+D+AARN L+ G VKI+D G++R+IY ADYY+
Sbjct: 591 DFLHIAIQIAAGMEYLSSHFFVHKDLAARNILI---GEQLHVKISDLGLSREIYSADYYR 647
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
K++LPI+WMPPEA + G F++ +D+WSFGV+LWE+FS G+ PY G +N+EV+E+V
Sbjct: 648 VQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMV 705
>UniRef50_Q16288 Cluster: NT-3 growth factor receptor precursor; n=49;
Euteleostomi|Rep: NT-3 growth factor receptor precursor -
Homo sapiens (Human)
Length = 839
Score = 184 bits (448), Expect = 1e-44
Identities = 104/264 (39%), Positives = 147/264 (55%), Gaps = 27/264 (10%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R + L + LG+GAFG+V+ + S +M VAVK L + T A DF EA +
Sbjct: 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD-PTLAARKDFQREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP--------KPERASA-L 965
+ H +IV GVC D P +V E + GDL FLR P +P +A L
Sbjct: 592 LTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGEL 651
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+ +L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y D
Sbjct: 652 GLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV---GANLLVKIGDFGMSRDVYSTD 708
Query: 1026 YYKK--------------GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGV 1071
YY+ GG MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G
Sbjct: 709 YYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGK 768
Query: 1072 MPYTGCANREVMELVSGGGRLEKP 1095
P+ +N EV+E ++ G LE+P
Sbjct: 769 QPWFQLSNTEVIECITQGRVLERP 792
>UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86;
Coelomata|Rep: Tyrosine-protein kinase Tec - Homo sapiens
(Human)
Length = 631
Score = 183 bits (446), Expect = 2e-44
Identities = 103/242 (42%), Positives = 140/242 (57%), Gaps = 18/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++ L ++ LG G FG V G +R A+ VA+K + E E DF+ EA
Sbjct: 364 EINPSELTFMRELGSGLFGVVRLGKWR------AQYKVAIKAIRE--GAMCEEDFIEEAK 415
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M K H +V L GVC + P +IV E + G L NFLR+ + R L+M C
Sbjct: 416 VMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSM-----C 470
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+G YLE FIHRD+AARNCL++ G VVK++DFGMAR + Y G A
Sbjct: 471 Q-DVCEGMEYLERNSFIHRDLAARNCLVSEAG---VVKVSDFGMARYVLDDQYTSSSG-A 525
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P+KW PPE + F++K+DVWSFGVL+WEVF+ G MP+ N EV+ +V+ G RL
Sbjct: 526 KFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLY 585
Query: 1094 KP 1095
+P
Sbjct: 586 QP 587
>UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,
isoform B; n=3; Endopterygota|Rep: PREDICTED: similar to
CG8874-PB, isoform B - Tribolium castaneum
Length = 801
Score = 183 bits (445), Expect = 3e-44
Identities = 99/255 (38%), Positives = 145/255 (56%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++ + + L+ +G+G FG+VY+ ++ S D + TLPE + FL E
Sbjct: 533 ELNNDDVVLLDKIGRGNFGDVYRAQLKN-SNDVVAVKTCRVTLPE----DHKKKFLQEGR 587
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I+ +++H NIV LIG+C + P IV+EL+ GG L FLR+ +ALT L+
Sbjct: 588 ILKQYDHPNIVKLIGICVQKQPIMIVMELVPGGSLLTFLRKK-------TALTDAQLMKM 640
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+D G RYLE+K IHRD+AARNCL+ G VVKI+DFGM+R+ +Y G
Sbjct: 641 CLDAAAGMRYLESKNCIHRDLAARNCLV---GYNNVVKISDFGMSRE--EEEYIVSDGMK 695
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+PIKW PEA G +T+ DVWS+G+L WE+FS G PY+G +N + E + G R+
Sbjct: 696 QIPIKWTAPEALNFGKYTSLCDVWSYGILCWEIFSRGGTPYSGLSNSKAREKIDAGYRMP 755
Query: 1094 KPYGEGSEYHKFKRR 1108
P E ++ R
Sbjct: 756 APDNTPDEMYRLMLR 770
>UniRef50_UPI0000D55449 Cluster: PREDICTED: similar to CG7223-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7223-PA, isoform A - Tribolium castaneum
Length = 861
Score = 183 bits (445), Expect = 3e-44
Identities = 102/254 (40%), Positives = 147/254 (57%), Gaps = 15/254 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R L L K+LG+GAFG+V + A VAVK L E T D + E
Sbjct: 527 EIPRSMLCLGKSLGEGAFGKVVKAEAVGLLKPGASSIVAVKMLKEGHTDNEMMDLVSEME 586
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPERA 962
+M H NI++L+G C P ++V+E G+L++FLR+ RP + +
Sbjct: 587 MMKMIGKHNNIINLLGCCTQGGPLYVVVEYAPYGNLRDFLRQHRPSSGYEPAIGLEEKEK 646
Query: 963 SALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
LT KDL+ + V +G YL ++R IHRD+AARN L++ +KIADFG+ARDI+
Sbjct: 647 KTLTQKDLVSFAYQVARGMEYLASRRCIHRDLAARNVLVSD---DYFLKIADFGLARDIH 703
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE- 1081
DYY+K LP+KWM PEA V+TT++DVWS+G+LLWE+ +LG PY + E
Sbjct: 704 CNDYYRKTTDGRLPVKWMAPEALFHRVYTTQSDVWSYGILLWEIMTLGGTPYPSVPSVEK 763
Query: 1082 VMELVSGGGRLEKP 1095
+ +L+ G R+EKP
Sbjct: 764 LFQLLRNGHRMEKP 777
>UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54;
Gnathostomata|Rep: Tyrosine-protein kinase BTK - Homo
sapiens (Human)
Length = 659
Score = 183 bits (445), Expect = 3e-44
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 447
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 502
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 503 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 557
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 558 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 617
Query: 1094 KPY 1096
+P+
Sbjct: 618 RPH 620
>UniRef50_Q7PYY7 Cluster: ENSANGP00000019144; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019144 - Anopheles gambiae
str. PEST
Length = 687
Score = 182 bits (443), Expect = 5e-44
Identities = 96/246 (39%), Positives = 138/246 (56%), Gaps = 10/246 (4%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R LK+ LG+GAFG+V++ AVKTL E ++ +D L E ++
Sbjct: 381 RHRLKVFNILGEGAFGQVWRCEATDIDGHEGVSVTAVKTLKENASEAERNDLLSELQVLK 440
Query: 917 KFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE------RASALTMKD 969
H N+V L+G C ++ P F++LE + G L+ FLR SR + ++ LT D
Sbjct: 441 SLEPHINVVRLLGCCTEKDPIFVILEYVNMGKLQTFLRNSRVEKHYGNTHGKSKILTSGD 500
Query: 970 LLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKK 1029
L V +G +L ++ IHRD+AARN L+T K+ADFG ARDI + Y++
Sbjct: 501 LTSFMYQVARGMDFLTSRGIIHRDLAARNILITD---DHTCKVADFGFARDIVTSKVYER 557
Query: 1030 GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGG 1089
+ LPI+WM E+ D +FT K+D+WSFG+L+WE+ +LG PY G A +VM V G
Sbjct: 558 KSEGRLPIRWMATESLYDNIFTVKSDIWSFGILMWEIVTLGSTPYPGIAAADVMRKVRDG 617
Query: 1090 GRLEKP 1095
RLEKP
Sbjct: 618 YRLEKP 623
>UniRef50_Q6TYB9 Cluster: Dauer abnormal formation-2 precursor; n=2;
Caenorhabditis briggsae|Rep: Dauer abnormal formation-2
precursor - Caenorhabditis briggsae
Length = 1807
Score = 182 bits (442), Expect = 6e-44
Identities = 99/259 (38%), Positives = 150/259 (57%), Gaps = 13/259 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAES-DFLM 910
++ +ES+ L + +GQG FG+VY QG A P AVK E + E+ ++LM
Sbjct: 1197 ELEKESVTLGEVIGQGTFGKVYLAQGKKCVSIRGDAFGPCAVKINTEEAAESLENMNYLM 1256
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP-------ERAS 963
EA +M F IV L GV HP ++V+E + G+L+++LR R + +
Sbjct: 1257 EANVMKNFKTTFIVKLFGVVSSVHPAWVVMEFMELGNLRDYLRAKREEEVFDENNCNFYN 1316
Query: 964 ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYR 1023
+ + + + +C G YLE+ +F HRD+AARNC++ +VKI DFGMARD++
Sbjct: 1317 IVPREKICEWAAQICDGMAYLESLKFCHRDLAARNCMIDKT---ELVKIGDFGMARDLFY 1373
Query: 1024 ADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM 1083
DYYK GK M+P++WM PE+ DG F +K+D+WSFGV+L+E+ +LG PY G +N EV+
Sbjct: 1374 HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDIWSFGVVLYELITLGAQPYIGLSNDEVL 1433
Query: 1084 ELVSGGGRLEKPYGEGSEY 1102
+ ++ K SEY
Sbjct: 1434 NYIGMARKVIKKPDCCSEY 1452
>UniRef50_Q95YM9 Cluster: Fibroblast growth factor receptor precursor;
n=4; Ascidiacea|Rep: Fibroblast growth factor receptor
precursor - Halocynthia roretzi (Sea squirt)
Length = 763
Score = 182 bits (442), Expect = 6e-44
Identities = 106/276 (38%), Positives = 152/276 (55%), Gaps = 25/276 (9%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQG-LYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
++ RE + LV+ L +G FG+V++ L + +M AVK L + D L E
Sbjct: 376 ELQREDITLVERLDEGFFGQVFKADLVTCNNTRKEKMVCAVKMLKGNRNEKDVLDLLTEM 435
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPK------------- 958
M + H NI++L+GVC P ++V+E A G+L+++LR +RP+
Sbjct: 436 DQMKRVGKHKNIINLLGVCTQNGPLWLVIEYAAQGNLRDYLRRNRPQNTLCNLVLPSEGR 495
Query: 959 -PE------RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVK 1011
P+ LT KD++ + V +G +L K+ IHRD+AARN L+T V+K
Sbjct: 496 NPDDELPVPHGDTLTQKDIVSFAFQVARGLEFLAQKKCIHRDLAARNVLVTEE---LVMK 552
Query: 1012 IADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGV 1071
IADFG+ARDI DYY+K + LP KWM EA D +FT TDVWSFGVLLWE+FSL
Sbjct: 553 IADFGLARDIRSCDYYRKHTRGHLPYKWMALEAMSDNIFTHATDVWSFGVLLWEIFSLAG 612
Query: 1072 MPYTGCANREVMELVSGGGRLEKPYGEGSEYHKFKR 1107
PY G E+++ + G RL+KP E ++ R
Sbjct: 613 SPYPGIKTHELVKFLRSGERLDKPQYASQEMYRLMR 648
>UniRef50_Q7Z1D3 Cluster: Focal adhesion kinase; n=1; Lytechinus
variegatus|Rep: Focal adhesion kinase - Lytechinus
variegatus (Sea urchin)
Length = 1006
Score = 181 bits (441), Expect = 8e-44
Identities = 100/242 (41%), Positives = 147/242 (60%), Gaps = 14/242 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++SRE + LV+ +GQG FG+V++G+Y + ++ VAVKT ST FL EA
Sbjct: 432 EISRELVTLVETIGQGQFGDVHKGIYIDQDE---KVEVAVKTCKVESTQALGERFLEEAY 488
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +F+H +I+ LIGVC D P +IV+EL G+++ FL+ + + LT+ L+L
Sbjct: 489 IMKQFDHPHIIKLIGVCTDP-PIWIVMELAPFGEMRMFLQTHKEE------LTLASLILY 541
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE+K+F+HRDIAARN L+ ++ VK+ DFG++R ++ YYK K
Sbjct: 542 AYQLSMALSYLESKKFVHRDIAARNLLVVAKDN---VKLGDFGLSRLLHDHSYYK-ASKG 597
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LPIKWM PE+ FT+ +DVW FGV +WE+ GV P+ G N EV+ + G RL
Sbjct: 598 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNEVIGRIENGERLP 657
Query: 1094 KP 1095
P
Sbjct: 658 MP 659
>UniRef50_UPI00004D86FC Cluster: Tyrosine-protein kinase Tec (EC
2.7.10.2).; n=1; Xenopus tropicalis|Rep: Tyrosine-protein
kinase Tec (EC 2.7.10.2). - Xenopus tropicalis
Length = 647
Score = 181 bits (440), Expect = 1e-43
Identities = 101/242 (41%), Positives = 138/242 (57%), Gaps = 18/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++ L +K LG G FG V G +R A+ VA+K + E +E DF+ EA
Sbjct: 406 EINPSELTFMKELGSGLFGVVRLGKWR------AQYKVAIKAIRE--GAMSEEDFIEEAK 457
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M K H +V L GVC + P +IV E + G L N+LR+ R + LL
Sbjct: 458 VMMKLTHLKLVQLYGVCTQQRPIYIVTEFMEHGCLLNYLRQ------RHGQFSPDILLSM 511
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE FIHRD+AARNCL+ G VVK++DFGM R + Y G A
Sbjct: 512 CQDVCEAMSYLEQNNFIHRDLAARNCLVNDAG---VVKVSDFGMTRYVLDDQYTSSCG-A 567
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P+KW PPE + F++K+DVWSFGVL+WEVF+ G MP+ +N EV+E+V+ G RL
Sbjct: 568 KFPVKWSPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGKMPFESYSNVEVVEMVTRGERLY 627
Query: 1094 KP 1095
+P
Sbjct: 628 RP 629
>UniRef50_Q9Y1Y3 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 181 bits (440), Expect = 1e-43
Identities = 97/243 (39%), Positives = 145/243 (59%), Gaps = 15/243 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + +KLV+ +G G FG VY+G++ R +P+AVKTL S+ + DFL EA+
Sbjct: 529 EIPPKYIKLVEEIGGGEFGTVYKGMWNERKPP---VPIAVKTLKPGSSDKMRDDFLTEAS 585
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +F+H N++ L GV P I++E + G L +LR + K L+++ LL
Sbjct: 586 IMGQFHHPNVIKLYGVITKVEPAMIIMEFMDNGSLYYYLRHNDEK------LSLQQLLKM 639
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADY-YKKGGK 1032
+ V G +YL ++HRD+AARN L++ V K+ADFG++R+ +Y KKGGK
Sbjct: 640 ACGVAAGMQYLSEVGYVHRDLAARNILVSK---DEVCKVADFGLSRETTNDEYDVKKGGK 696
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
+P++W PEA FTT +DVWS+GVLLWEV S G PY N+ V++ + G RL
Sbjct: 697 --IPVRWTAPEAISYRKFTTASDVWSYGVLLWEVMSYGQQPYEDWDNQMVLDKLESGYRL 754
Query: 1093 EKP 1095
+KP
Sbjct: 755 QKP 757
>UniRef50_Q008W6 Cluster: Gamma-carboxyglutamic acid protein 1; n=2;
Ascidiacea|Rep: Gamma-carboxyglutamic acid protein 1 -
Ciona intestinalis (Transparent sea squirt)
Length = 556
Score = 181 bits (440), Expect = 1e-43
Identities = 95/247 (38%), Positives = 140/247 (56%), Gaps = 17/247 (6%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
V RE L+L + + G FG+VY+G R R + VAVK+L L + FL E +
Sbjct: 167 VERERLQLGEVITSGNFGDVYRGKLRSRQNTWHD--VAVKSLKSLENHEDVEKFLREGVM 224
Query: 915 MAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTMK 968
M +H N++ LIGVC D I+L + GDL+ FLR+ + LT+
Sbjct: 225 MRGLDHRNVLALIGVCVDGEVERLQTSPLIILPFMENGDLRTFLRDGN------NVLTVL 278
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
LL DV G YL K+F+HRD+AARNC++ VK+ADFG++RD++ DYY+
Sbjct: 279 KLLKFCKDVAMGMEYLAEKKFVHRDLAARNCMVDKNW---CVKVADFGLSRDLFDRDYYR 335
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K LP+KWMPPE+ G + K+DVWS+G++ WE+ + G +PY +++ +S
Sbjct: 336 SSVKTQLPLKWMPPESIKYGRYGEKSDVWSYGIVCWEIMTRGAIPYPTVQAVAILQYLSE 395
Query: 1089 GGRLEKP 1095
G R+E+P
Sbjct: 396 GNRMERP 402
>UniRef50_A7RZ71 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 624
Score = 179 bits (436), Expect = 3e-43
Identities = 97/253 (38%), Positives = 143/253 (56%), Gaps = 14/253 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + + LG+GAFG V + + VAVK L +T +D L E
Sbjct: 328 EIDRSQITIKEQLGEGAFGLVMKAEALGLTDMPYRHTVAVKMLKADATENELADLLSEMD 387
Query: 914 IMAKF-NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS--------- 963
M +H NI++LIG C P ++V+E G+L+ FLRE RP S
Sbjct: 388 TMKNIGSHKNIINLIGACTQNGPLYVVVEFAPHGNLRQFLRERRPSDYHRSRSDSSTHSQ 447
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+L ++D + + + +G YL K+ IHRD+AARN L+ G V+KIADFG+AR++
Sbjct: 448 PSLIVRDFISFAFQIARGMEYLSFKKCIHRDLAARNILV---GEDYVMKIADFGLARNVR 504
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYY+K LPIKW+ EA D V+TT++DVW+FG+LLWE+F+LG PY G ++
Sbjct: 505 DMDYYRKATDGRLPIKWLAIEALFDRVYTTQSDVWTFGILLWEIFTLGGSPYPGIPVEKL 564
Query: 1083 MELVSGGGRLEKP 1095
EL+ G R++ P
Sbjct: 565 FELLKSGYRMQMP 577
>UniRef50_A3EXK4 Cluster: Fibroblast growth factor receptor a; n=1;
Nematostella vectensis|Rep: Fibroblast growth factor
receptor a - Nematostella vectensis
Length = 441
Score = 179 bits (436), Expect = 3e-43
Identities = 97/253 (38%), Positives = 143/253 (56%), Gaps = 14/253 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + + LG+GAFG V + + VAVK L +T +D L E
Sbjct: 113 EIDRSQITIKEQLGEGAFGLVMKAEALGLTDMPYRHTVAVKMLKADATENELADLLSEMD 172
Query: 914 IMAKF-NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS--------- 963
M +H NI++LIG C P ++V+E G+L+ FLRE RP S
Sbjct: 173 TMKNIGSHKNIINLIGACTQNGPLYVVVEFAPHGNLRQFLRERRPSDYHRSRSDSSTHSQ 232
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+L ++D + + + +G YL K+ IHRD+AARN L+ G V+KIADFG+AR++
Sbjct: 233 PSLIVRDFISFAFQIARGMEYLSFKKCIHRDLAARNILV---GEDYVMKIADFGLARNVR 289
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYY+K LPIKW+ EA D V+TT++DVW+FG+LLWE+F+LG PY G ++
Sbjct: 290 DMDYYRKATDGRLPIKWLAIEALFDRVYTTQSDVWTFGILLWEIFTLGGSPYPGIPVEKL 349
Query: 1083 MELVSGGGRLEKP 1095
EL+ G R++ P
Sbjct: 350 FELLKSGYRMQMP 362
>UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine
protein kinase BTK; n=1; Danio rerio|Rep: PREDICTED:
similar to tyrosine protein kinase BTK - Danio rerio
Length = 596
Score = 179 bits (435), Expect = 5e-43
Identities = 96/242 (39%), Positives = 141/242 (58%), Gaps = 18/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ L ++ LG G FG V G ++ R VA+K + E S +E DF+ EA
Sbjct: 331 EIDPRQLTFIRELGNGQFGVVKYGKWQGRH------DVAIKMVKEGS--MSEDDFIEEAK 382
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M K H N+V L GVC + P +IV E LA G L N+L+E P + L M C
Sbjct: 383 VMMKLCHGNLVQLYGVCTKQRPIYIVTEYLANGCLLNYLQEGLLNPTSIALLEM-----C 437
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DV +G +YLE +FIHRD+AARNCL+ S G +K+ DFG++R + +Y G +
Sbjct: 438 K-DVSEGMKYLEANQFIHRDLAARNCLVDSNG---TIKVTDFGLSRYVLDDEYTSSVG-S 492
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE+++ G MPY N E++E +S G RL
Sbjct: 493 KFPVRWSPPEVLLYCKFSSKSDIWAFGVLMWEIYTQGRMPYDRWNNTEIVEKISAGHRLY 552
Query: 1094 KP 1095
+P
Sbjct: 553 RP 554
>UniRef50_UPI00015A7C25 Cluster: UPI00015A7C25 related cluster; n=3;
Danio rerio|Rep: UPI00015A7C25 UniRef100 entry - Danio
rerio
Length = 759
Score = 179 bits (435), Expect = 5e-43
Identities = 105/248 (42%), Positives = 148/248 (59%), Gaps = 21/248 (8%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA- 913
+ + + L +++G+G FGEV+ G R RS + PVAVK E + ++ FLMEAA
Sbjct: 486 LEHDDVILGQSIGRGNFGEVFSG--RLRSDNT---PVAVKACRENLPAEHKNKFLMEAAR 540
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I+ +++H NIV LIGVC + P +I++EL+ GGD FLR + + + M +
Sbjct: 541 ILKQYDHPNIVKLIGVCTQKQPIYIIMELVQGGDFLTFLRTEGHNLKSSMLIRMAE---- 596
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+V G YLE+K+ IHRD+AARNCL+ G VVKI+DFGM+R+ Y GG
Sbjct: 597 --NVASGLAYLESKKCIHRDVAARNCLV---GEESVVKISDFGMSREEQDGVYSATGGMK 651
Query: 1034 MLPIKWMPPEAY---IDGVFTTKTDVWSFGVLLWEVFSLGVMPY---TGCANREVMELVS 1087
+P+KW PEA G +TT++DVWSFGVLLWE FS GV PY T +N++ + V
Sbjct: 652 QIPVKWTAPEALNYGSPGRYTTESDVWSFGVLLWETFSRGVTPYTIPTVMSNQQTRDEVE 711
Query: 1088 GGGRLEKP 1095
G R+ P
Sbjct: 712 RGYRMPAP 719
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 179 bits (435), Expect = 5e-43
Identities = 105/242 (43%), Positives = 143/242 (59%), Gaps = 18/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R S+KL + LG G FGEV++G + + VAVKTL E + FL EA
Sbjct: 296 EIPRRSIKLERKLGNGQFGEVWEGTWN------GTVRVAVKTLKE--GAMDPTAFLQEAN 347
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM K H +V L+ VC + P +IV EL+ G L ++L E K R +L+
Sbjct: 348 IMKKLRHPKLVALLAVCSEGEPIYIVTELMTNGCLLDYLHEGEGKQLREP-----ELIDI 402
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ V G YLE++RF+HRD+AARN L+ G R K+ADFG++R I +Y K G A
Sbjct: 403 TAQVADGMAYLESQRFVHRDLAARNILV---GDLRNCKVADFGLSR-IIEDEYIAKEG-A 457
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+PIKW PEA G FT K+DVWSFG+L++EV + G +PY G NREV++ VS G R+
Sbjct: 458 KMPIKWTAPEAINFGKFTIKSDVWSFGILIYEVITKGRVPYPGMVNREVLDQVSRGYRMP 517
Query: 1094 KP 1095
KP
Sbjct: 518 KP 519
>UniRef50_Q12866 Cluster: Proto-oncogene tyrosine-protein kinase MER
precursor; n=30; root|Rep: Proto-oncogene
tyrosine-protein kinase MER precursor - Homo sapiens
(Human)
Length = 999
Score = 179 bits (435), Expect = 5e-43
Identities = 93/247 (37%), Positives = 144/247 (58%), Gaps = 12/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE-SDFLMEAA 913
+ R L L K LG+G FG V +G + D + VAVKT+ ++ E +FL EAA
Sbjct: 582 IDRNLLILGKILGEGEFGSVMEGNLKQE--DGTSLKVAVKTMKLDNSSHREIEEFLSEAA 639
Query: 914 IMAKFNHANIVHLIGVCFDRHPR-----FIVLELLAGGDLKNFLRESRPKPERASALTMK 968
M F+H N++ L+GVC + + ++L + GDL +L SR + + ++
Sbjct: 640 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETG-PKHIPLQ 698
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
LL VD+ G YL + F+HRD+AARNC+L V +ADFG+++ IY DYY+
Sbjct: 699 TLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRD---DMTVCVADFGLSKKIYSGDYYR 755
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+G A +P+KW+ E+ D V+T+K+DVW+FGV +WE+ + G+ PY G N E+ + +
Sbjct: 756 QGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIRTRGMTPYPGVQNHEMYDYLLH 815
Query: 1089 GGRLEKP 1095
G RL++P
Sbjct: 816 GHRLKQP 822
>UniRef50_Q70W11 Cluster: Receptor tyrosine kinase X; n=1; Ciona
intestinalis|Rep: Receptor tyrosine kinase X - Ciona
intestinalis (Transparent sea squirt)
Length = 478
Score = 178 bits (434), Expect = 6e-43
Identities = 103/266 (38%), Positives = 148/266 (55%), Gaps = 18/266 (6%)
Query: 839 SESFLPQGIDVRGLPQVSRESLKLVKA--LGQGAFGEVYQGLY-----RHRSADAAEMPV 891
SE PQ + +SR L + K +G+G FG VY G Y + + + V
Sbjct: 121 SEQLSPQILQEMSSVLISRNKLMVDKENIIGKGHFGTVYNGEYITSEISKLNGNPIKRKV 180
Query: 892 AVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPR-FIVLELLAGGDLKN 950
A+KTL ++ ++ FL E +M+ F+ N++ LIG+ +D +VL + GDL
Sbjct: 181 AIKTLSKIEDTESVEKFLKEGLMMSDFHDENVLTLIGISWDDDGAPMVVLPYMMHGDLLQ 240
Query: 951 FLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVV 1010
F+R+ P T+KDL+ + CKG YL ++RF+HRD+AARNC+L VV
Sbjct: 241 FIRKPSNNP------TVKDLVGFGLQACKGMCYLASQRFVHRDLAARNCMLNET---YVV 291
Query: 1011 KIADFGMARDIYRADYYKKGGKA-MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL 1069
K+ADFG+ARDIY +YYK A +P+KWM E+ FT KTDVWSFG+LLWE+ +
Sbjct: 292 KVADFGLARDIYEKEYYKPHEHAGRMPVKWMALESLQQQTFTIKTDVWSFGILLWELLTR 351
Query: 1070 GVMPYTGCANREVMELVSGGGRLEKP 1095
GV PY +V+ + G RL +P
Sbjct: 352 GVTPYPDVDAFDVVNYILDGRRLRQP 377
>UniRef50_UPI0000D569CE Cluster: PREDICTED: similar to CG10023-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG10023-PA, isoform A - Tribolium castaneum
Length = 1106
Score = 178 bits (433), Expect = 8e-43
Identities = 96/242 (39%), Positives = 143/242 (59%), Gaps = 12/242 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R+ ++L + LG+G FG+V++G Y+ + D + +PVAVKT + FL EA
Sbjct: 422 ELQRDQIQLGEILGEGQFGDVHKGTYKAK--DGSLIPVAVKTCKREADLNTTEKFLEEAY 479
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM KF+H +I+ LIGVC + P +IV+EL G+L+ +L+ ++ L + LLL
Sbjct: 480 IMQKFDHQHIIKLIGVCSES-PVWIVMELAKLGELRAYLQNNKDD------LDLATLLLY 532
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE+K+F+HRDIAARN L++S VK+ DFG++R + Y K K
Sbjct: 533 AFQLSTALSYLESKKFVHRDIAARNVLVSSHTS---VKLGDFGLSRSMNDDQSYYKASKG 589
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LPIKWM PE+ FT +DVW FGV +WE+ G+ P+ G N EV+ + G RL
Sbjct: 590 KLPIKWMSPESINFRRFTIASDVWMFGVCMWEILMYGIKPFQGVKNNEVLTKIENGERLA 649
Query: 1094 KP 1095
P
Sbjct: 650 LP 651
>UniRef50_Q7YSY1 Cluster: Fes-like tyrosine kinase protein; n=1;
Schistosoma mansoni|Rep: Fes-like tyrosine kinase protein
- Schistosoma mansoni (Blood fluke)
Length = 1259
Score = 177 bits (432), Expect = 1e-42
Identities = 97/243 (39%), Positives = 143/243 (58%), Gaps = 19/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEA 912
++ ++L++ +GQG FG+VY+G+Y + E VAVKT +++ FL
Sbjct: 955 ELDNRDVQLLQKIGQGNFGDVYRGVY-----NGCE--VAVKTCRVDMTASDLRRKFLQGE 1007
Query: 913 AIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLL 972
FNH NIV L+G+ +P IV+E + GG L N LR+S+ +AL + LL
Sbjct: 1008 TTALNFNHPNIVKLVGIAVQSYPIMIVMEYVPGGSLLNHLRKSK------NALPVMKLLQ 1061
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK 1032
S+D G YLE + IHRD+AARNCL++ G +KIADFGM+R+ + + K G+
Sbjct: 1062 MSLDAANGMMYLEARNCIHRDLAARNCLISDDGQ---LKIADFGMSREEHIYELSDKRGQ 1118
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
+PIKW PEA G +T K DVWS+GVLLWE+F+ G +PY +N++ +++ G RL
Sbjct: 1119 --IPIKWTAPEALRTGRYTIKCDVWSYGVLLWEIFTFGDVPYRNWSNQQTRDMIESGYRL 1176
Query: 1093 EKP 1095
P
Sbjct: 1177 PAP 1179
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming protein
Abl; n=15; root|Rep: Tyrosine-protein kinase transforming
protein Abl - Abelson murine leukemia virus
Length = 746
Score = 177 bits (432), Expect = 1e-42
Identities = 100/254 (39%), Positives = 147/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 122 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 174
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + SA+ LL
Sbjct: 175 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNR--QEVSAVV---LLYM 229
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 230 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 285
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 286 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 345
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 346 RPEGCPEKVYELMR 359
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 177 bits (432), Expect = 1e-42
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 334
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 335 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 389
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 390 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 445
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 446 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 505
Query: 1094 KPYG 1097
+P G
Sbjct: 506 QPEG 509
>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
Tyrosine kinase - Sycon raphanus
Length = 879
Score = 177 bits (431), Expect = 1e-42
Identities = 91/241 (37%), Positives = 142/241 (58%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+S +++ + + +G+G FG+V++G + + + A + P+ + FL EA I
Sbjct: 615 ISHDNILIGEKIGKGNFGDVFKGYLKTHNMEVAVKSCRSEDFPD------KQKFLQEAEI 668
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ ++ H NIV LIGVC ++ P +I++EL+AGG+ +FLR K + + LT +C
Sbjct: 669 LKQYRHPNIVELIGVCAEKEPLYIIMELMAGGNFLSFLRGPEGKRLKVNNLTE----MC- 723
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V+ G +LE + IHRD+AARNCL+ G V+KI+DFGM+R+ Y G
Sbjct: 724 VEAAAGMVFLEQRNCIHRDLAARNCLV---GDNNVLKISDFGMSREEDDGIYTVSSGLKQ 780
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+PIKW PEA G +TT++DVWS+G+LLWE ++ G PY G NRE E + R+ +
Sbjct: 781 IPIKWTSPEALNYGRYTTQSDVWSYGILLWETYTYGSGPYPGMNNRETRERIESNYRMPR 840
Query: 1095 P 1095
P
Sbjct: 841 P 841
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-oncogene
tyrosine-protein kinase abl1; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to proto-oncogene
tyrosine-protein kinase abl1 - Nasonia vitripennis
Length = 1522
Score = 177 bits (430), Expect = 2e-42
Identities = 98/255 (38%), Positives = 147/255 (57%), Gaps = 16/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++R + + LG G +G+VY+ +++ + M VAVKTL E + A DFL EAA
Sbjct: 284 EINRTDIVMRHKLGGGQYGDVYEAVWKRYN-----MTVAVKTLKEDT--MALKDFLEEAA 336
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM + H N+V LIGVC P +I+ E ++ G+L ++LR E + L+
Sbjct: 337 IMKEMKHRNLVQLIGVCTREPPFYIITEFMSKGNLLDYLRN-----ESKHQINAVVLMHM 391
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + G YLE++ FIHRD+AARNCL+ G +VK+ADFG+AR + R D Y A
Sbjct: 392 ATQIASGMSYLESRNFIHRDLAARNCLV---GESHLVKVADFGLAR-LMRDDTYTAHAGA 447
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE F+TK+DVW+FG+LLWE+ + G+ PY G +V ++ G R+E
Sbjct: 448 KFPIKWTAPEGLAYNKFSTKSDVWAFGILLWEIATYGMSPYPGVDLTDVYHMLEKGYRME 507
Query: 1094 KPYGEGSEYHKFKRR 1108
P G + ++ R+
Sbjct: 508 CPPGCPPKVYELMRQ 522
>UniRef50_Q05397 Cluster: Focal adhesion kinase 1; n=111;
Euteleostomi|Rep: Focal adhesion kinase 1 - Homo sapiens
(Human)
Length = 1052
Score = 177 bits (430), Expect = 2e-42
Identities = 95/242 (39%), Positives = 145/242 (59%), Gaps = 13/242 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ RE ++L + +G+G FG+V+QG+Y S + + VA+KT ++ FL EA
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYM--SPENPALAVAIKTCKNCTSDSVREKFLQEAL 473
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
M +F+H +IV LIGV + +P +I++EL G+L++FL+ R +L + L+L
Sbjct: 474 TMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQV------RKYSLDLASLILY 526
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE+KRF+HRDIAARN L++S VK+ DFG++R + + YYK K
Sbjct: 527 AYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYMEDSTYYK-ASKG 582
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LPIKWM PE+ FT+ +DVW FGV +WE+ GV P+ G N +V+ + G RL
Sbjct: 583 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 642
Query: 1094 KP 1095
P
Sbjct: 643 MP 644
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 177 bits (430), Expect = 2e-42
Identities = 101/255 (39%), Positives = 145/255 (56%), Gaps = 16/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+ +++ VAVKTL E + A DFL EAA
Sbjct: 365 EICRTDIMMKHKLGGGQYGEVYEAVWKRYGNT-----VAVKTLKEDT--MALKDFLEEAA 417
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM + H N+V LIGVC P +I+ E ++ G+L +FLR + + A AL L
Sbjct: 418 IMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVAL-----LYM 472
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + G YLE++ +IHRD+AARNCL+ G ++VK+ADFG+AR + R D Y A
Sbjct: 473 ATQIASGMSYLESRNYIHRDLAARNCLV---GDNKLVKVADFGLAR-LMRDDTYTAHAGA 528
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE F+TK+DVW+FGVLLWE+ + G+ PY +V + G R+E
Sbjct: 529 KFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRME 588
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G E + R+
Sbjct: 589 RPPGCPPEVYDLMRQ 603
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ABL1;
n=35; root|Rep: Proto-oncogene tyrosine-protein kinase
ABL1 - Homo sapiens (Human)
Length = 1130
Score = 177 bits (430), Expect = 2e-42
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 288
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 289 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 343
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 344 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 399
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 400 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 459
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 460 RPEGCPEKVYELMR 473
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 176 bits (429), Expect = 2e-42
Identities = 102/244 (41%), Positives = 141/244 (57%), Gaps = 17/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + S+ L + +GQG FGEV++ ++ + VAVKTL S A DFL EA
Sbjct: 340 EIPKSSIILKEKIGQGQFGEVFKAVWNKTTI------VAVKTLKPSSCDAA--DFLREAQ 391
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
M + +H N++ L VC P +IV E ++ G L N+L+ PE +AL M+ L++
Sbjct: 392 TMKRLHHPNLIQLYAVCTQTEPFYIVTEYMSKGSLLNYLQS----PE-GNALNMQCLIMM 446
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + G YLE++R IHRD+AARN L+ G VKIADFG+AR I+ +Y G A
Sbjct: 447 AAKIAPGMAYLESRRHIHRDLAARNVLV---GEQHAVKIADFGLARMIHNREYVAHAG-A 502
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PEA FT K+DVWSFG+LL E+ + G PY G N EV+ V G R+
Sbjct: 503 RFPIKWTSPEAANYSRFTIKSDVWSFGILLTEIVTYGRSPYPGMHNAEVLRQVDAGYRMS 562
Query: 1094 KPYG 1097
KP G
Sbjct: 563 KPPG 566
>UniRef50_Q2VJ45 Cluster: HOOK3-RET fusion protein; n=3; Eutheria|Rep:
HOOK3-RET fusion protein - Homo sapiens (Human)
Length = 776
Score = 176 bits (429), Expect = 2e-42
Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 383 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 442
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 443 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 502
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 503 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 559
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 560 DVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 619
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 620 ERLFNLLKTGHRMERPDNCSEEMYR 644
>UniRef50_P07949 Cluster: Proto-oncogene tyrosine-protein kinase
receptor ret precursor; n=59; Eumetazoa|Rep:
Proto-oncogene tyrosine-protein kinase receptor ret
precursor - Homo sapiens (Human)
Length = 1114
Score = 176 bits (429), Expect = 2e-42
Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 721 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 780
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 781 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 840
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 841 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 897
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 898 DVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 957
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 958 ERLFNLLKTGHRMERPDNCSEEMYR 982
>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 757
Score = 176 bits (429), Expect = 2e-42
Identities = 100/244 (40%), Positives = 148/244 (60%), Gaps = 17/244 (6%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ +ES+ K LG G FG V +G++ S E+ VA+KTL + Q E +FL EA +
Sbjct: 479 ILKESISFGKELGVGEFGSVIKGIWL--SPGGKEINVAMKTLHKDKMVQGEKEFLREALV 536
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M++ NH IV L+GVC P +V EL+ G L ++L + +P+ + DL L +
Sbjct: 537 MSQLNHPCIVSLLGVCLGP-PMILVQELVEMGALLDYLMDYQPEIQEV------DLKLWA 589
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYR-ADYY--KKGG 1031
+ G YLE KRF+HRD+AARN LL ++ + VKI+DFG++R + +DYY K+GG
Sbjct: 590 SQIAFGMMYLELKRFVHRDLAARNILLANK---KQVKISDFGLSRAVGTGSDYYQAKQGG 646
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+ P++W PE+ G F+TK+DVWS+G+ LWE+F+ G +PY EV+ + GR
Sbjct: 647 R--WPVRWYAPESINYGTFSTKSDVWSYGITLWEMFTFGDLPYGEMTGNEVVSFLEHCGR 704
Query: 1092 LEKP 1095
LEKP
Sbjct: 705 LEKP 708
>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
Drosophila melanogaster (Fruit fly)
Length = 786
Score = 176 bits (429), Expect = 2e-42
Identities = 102/236 (43%), Positives = 134/236 (56%), Gaps = 16/236 (6%)
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN 919
L L++ LG G FG V +G +R + AVK + E + +E DF+ EA +M K
Sbjct: 526 LMLMEELGSGQFGVVRRGKWR------GSIDTAVKMMKEGT--MSEDDFIEEAKVMTKLQ 577
Query: 920 HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCK 979
H N+V L GVC P +IV E + G L N+LR + E+ M LL + V K
Sbjct: 578 HPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLR----RHEKTLIGNMGLLLDMCIQVSK 633
Query: 980 GCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKW 1039
G YLE +IHRD+AARNCL+ G VVK+ADFG+AR + Y GG PIKW
Sbjct: 634 GMTYLERHNYIHRDLAARNCLV---GSENVVKVADFGLARYVLDDQYTSSGG-TKFPIKW 689
Query: 1040 MPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
PPE F++K+DVW++GVL+WE+F+ G MPY N EV+E V G LEKP
Sbjct: 690 APPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKP 745
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis mellifera
Length = 1439
Score = 176 bits (428), Expect = 3e-42
Identities = 97/255 (38%), Positives = 147/255 (57%), Gaps = 16/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++R + + LG G +G+VY+ +++ + M VAVKTL E + A DFL EAA
Sbjct: 283 EINRTDIVMRHKLGGGQYGDVYEAVWKRYN-----MTVAVKTLKEDT--MALKDFLEEAA 335
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM + H N+V L+GVC P +I+ E ++ G+L ++LR E + L+
Sbjct: 336 IMKEMKHRNLVQLLGVCTREPPFYIITEFMSKGNLLDYLRN-----ESKHQINAVVLMHM 390
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + G YLE++ FIHRD+AARNCL+ G +VK+ADFG+AR + R D Y A
Sbjct: 391 ATQIASGMSYLESRNFIHRDLAARNCLV---GENHLVKVADFGLAR-LMRDDTYTAHAGA 446
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE F+TK+DVW+FG+LLWE+ + G+ PY G +V ++ G R+E
Sbjct: 447 KFPIKWTAPEGLAYNKFSTKSDVWAFGILLWEIATYGMSPYPGVDLTDVYHMLEKGYRME 506
Query: 1094 KPYGEGSEYHKFKRR 1108
P G + ++ R+
Sbjct: 507 CPPGCPPKVYELMRQ 521
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 176 bits (428), Expect = 3e-42
Identities = 106/247 (42%), Positives = 143/247 (57%), Gaps = 15/247 (6%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
L +S L L LGQG FG V +GLY+ AD ++ VAVKTL S G E +F E
Sbjct: 457 LSYISEHDLHLGAELGQGEFGSVLKGLYK--GADGKKIEVAVKTLRLDSQGHGEKEFARE 514
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESR-PKPERASALTMKDL 970
A IM NH IV LIG+ + P +V EL++ G L ++L E + P P+ LT+K
Sbjct: 515 AGIMVTLNHPCIVKLIGITNGK-PMMMVQELISMGALVDYLYERKQPIPD---VLTLK-- 568
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI-YRADYYKK 1029
L + ++ G YLETKRF+HRD+AARN L+ S + VKI+DFG++R + +DYYK
Sbjct: 569 -LWAAEIASGMMYLETKRFVHRDLAARNILVQSM---KQVKISDFGLSRAVGANSDYYKA 624
Query: 1030 GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG- 1088
P+KW PE+ G F+ +DVWS+G+ LWE+FS G PY EV++ V
Sbjct: 625 SQGGRWPVKWYAPESINFGTFSHASDVWSYGITLWEMFSFGDAPYGDMTGAEVLDRVENL 684
Query: 1089 GGRLEKP 1095
RLE P
Sbjct: 685 NYRLECP 691
>UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12;
Eumetazoa|Rep: Tyrosine-protein kinase Fps85D -
Drosophila melanogaster (Fruit fly)
Length = 1325
Score = 175 bits (427), Expect = 4e-42
Identities = 93/251 (37%), Positives = 141/251 (56%), Gaps = 16/251 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++S + + L++ +G+G FG+VY+ + D VAVKT + + FL E
Sbjct: 1057 ELSNDDVVLLERIGRGNFGDVYKAKLKSTKLD-----VAVKTCRMTLPDEQKRKFLQEGR 1111
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I+ +++H NIV LIG+C + P IV+EL+ GG L +LR++ ++ LT + +
Sbjct: 1112 ILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKN------SNGLTTRQQMGM 1165
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
D G RYLE+K IHRD+AARNCL+ VKI+DFGM+R+ +Y G
Sbjct: 1166 CRDAAAGMRYLESKNCIHRDLAARNCLVDLE---HSVKISDFGMSRE--EEEYIVSDGMK 1220
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+P+KW PEA G +T+ DVWS+G+L+WE+FS G PY+G N E + G R+
Sbjct: 1221 QIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMP 1280
Query: 1094 KPYGEGSEYHK 1104
P E ++
Sbjct: 1281 TPKSTPEEMYR 1291
>UniRef50_UPI00015B4CAE Cluster: PREDICTED: similar to
ENSANGP00000019144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000019144 - Nasonia
vitripennis
Length = 1220
Score = 175 bits (426), Expect = 6e-42
Identities = 98/249 (39%), Positives = 146/249 (58%), Gaps = 13/249 (5%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSA-DAAEMPVAVKTLPELSTGQAESDFLMEAAIM 915
R+ L+L LG+G FG+V++ + VAVKT+ E ++ + + D + E IM
Sbjct: 919 RDKLRLQTVLGEGNFGQVWKAEADDLTGHQGTTRLVAVKTVKEGASDREKEDLVRELEIM 978
Query: 916 AKF-NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP------ERASALTMK 968
+ +H N+V L+G C ++ P +++LE + G L +LR+ R + E ++ALT +
Sbjct: 979 QRVGSHPNVVTLLGCCTEQEPHYLILEYVMYGKLLAYLRDHRTRQDFYNFSEDSAALTSR 1038
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY- 1027
DL + V +G YL +K+ IHRD+AARN L+ ++ KIADFGM+R
Sbjct: 1039 DLTVFGYCVARGMEYLASKKIIHRDLAARNVLVDHN---KLCKIADFGMSRFANEDGEVI 1095
Query: 1028 -KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
+ G+ LPI+WM PE+ I +FTTKTDVWSFG+L+WE+ +LG PY REVM V
Sbjct: 1096 ETRHGRNALPIRWMAPESLIYSLFTTKTDVWSFGILMWEIVTLGSTPYPDMTAREVMRSV 1155
Query: 1087 SGGGRLEKP 1095
G RLE+P
Sbjct: 1156 QSGYRLERP 1164
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming protein
Abl; n=57; root|Rep: Tyrosine-protein kinase transforming
protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 175 bits (426), Expect = 6e-42
Identities = 98/254 (38%), Positives = 144/254 (56%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 185 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 237
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 238 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 292
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y
Sbjct: 293 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGT 348
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 349 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 408
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 409 RPEGCPEKVYELMR 422
>UniRef50_Q8INU0 Cluster: CG14396-PD, isoform D; n=10; Sophophora|Rep:
CG14396-PD, isoform D - Drosophila melanogaster (Fruit
fly)
Length = 1237
Score = 175 bits (425), Expect = 7e-42
Identities = 92/247 (37%), Positives = 139/247 (56%), Gaps = 12/247 (4%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
RE L+L LG+G FG+V +G + VAVK L + S L E ++
Sbjct: 770 REKLQLDTVLGEGEFGQVLKGFATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQ 829
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--------LTMK 968
+ +H N++ L+G C +++E G L+++LR SR K E A + +K
Sbjct: 830 EVSHPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSR-KIECAGVDFADGVEPVNVK 888
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + +CKG YL + +HRD+AARN LL G++ KI+DFG+ RD+Y D Y
Sbjct: 889 MVLTFAWQICKGMAYLSELKLVHRDLAARNVLLAD---GKICKISDFGLTRDVYEDDAYL 945
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K + +P+KWM PE+ D V+T+K+DVWSFGVL WE+ +LG PY G A + + L+
Sbjct: 946 KRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKT 1005
Query: 1089 GGRLEKP 1095
G R+++P
Sbjct: 1006 GYRMDRP 1012
>UniRef50_Q10656-2 Cluster: Isoform b of Q10656 ; n=4;
Caenorhabditis|Rep: Isoform b of Q10656 - Caenorhabditis
elegans
Length = 988
Score = 174 bits (424), Expect = 1e-41
Identities = 103/269 (38%), Positives = 148/269 (55%), Gaps = 31/269 (11%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R L LV LG+GAFGEV++ Y+ + E+ VAVK L + + D + E
Sbjct: 582 EVERSKLSLVHMLGEGAFGEVWKATYKETENN--EIAVAVKKLKMSAHEKELIDLVSEME 639
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA-------- 964
H N++ LIG C P ++V+EL G+L++FLR RPK E+A
Sbjct: 640 TFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDY 699
Query: 965 -----------------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPG 1007
LT + L+ + V +G +L +K+ IHRD+AARN L+ G G
Sbjct: 700 LEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLV---GDG 756
Query: 1008 RVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVF 1067
V+KI+DFG++RD++ DYY+K G LPIKWM EA V+T ++DVWS+GVLLWE+
Sbjct: 757 HVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIM 816
Query: 1068 SLGVMPYTGCANREVMELVSGGGRLEKPY 1096
+LG PY A E+ + G R+E P+
Sbjct: 817 TLGGTPYPTIAMPELYANLKEGYRMEPPH 845
>UniRef50_Q10656 Cluster: Myoblast growth factor receptor egl-15
precursor; n=7; Caenorhabditis elegans|Rep: Myoblast
growth factor receptor egl-15 precursor - Caenorhabditis
elegans
Length = 1040
Score = 174 bits (424), Expect = 1e-41
Identities = 103/269 (38%), Positives = 148/269 (55%), Gaps = 31/269 (11%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R L LV LG+GAFGEV++ Y+ + E+ VAVK L + + D + E
Sbjct: 634 EVERSKLSLVHMLGEGAFGEVWKATYKETENN--EIAVAVKKLKMSAHEKELIDLVSEME 691
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA-------- 964
H N++ LIG C P ++V+EL G+L++FLR RPK E+A
Sbjct: 692 TFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDY 751
Query: 965 -----------------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPG 1007
LT + L+ + V +G +L +K+ IHRD+AARN L+ G G
Sbjct: 752 LEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLV---GDG 808
Query: 1008 RVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVF 1067
V+KI+DFG++RD++ DYY+K G LPIKWM EA V+T ++DVWS+GVLLWE+
Sbjct: 809 HVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIM 868
Query: 1068 SLGVMPYTGCANREVMELVSGGGRLEKPY 1096
+LG PY A E+ + G R+E P+
Sbjct: 869 TLGGTPYPTIAMPELYANLKEGYRMEPPH 897
>UniRef50_Q7YZH7 Cluster: MBRTK2; n=1; Monosiga brevicollis|Rep:
MBRTK2 - Monosiga brevicollis
Length = 759
Score = 174 bits (423), Expect = 1e-41
Identities = 93/243 (38%), Positives = 138/243 (56%), Gaps = 7/243 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R S++L + LG GAFG+V++ + +R + E A K L + +A DFL E
Sbjct: 354 EVERRSVRLGEKLGNGAFGQVFRAWFCNRHS-GEERSCAAKALKPGAPFRARQDFLSEMT 412
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLL 972
+M + H NI+ + G C P +++EL G+L+++LR+ R + L + L
Sbjct: 413 VMKEIGAHPNIIGIFGHCLRDEPHILLVELAELGNLRDYLRKCRTSQSKPQLLGSRQLAD 472
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK 1032
+ + G +LE K IHRD+AARN LL+ KI DFG+AR I DY K
Sbjct: 473 FCLQIASGMSFLERKNVIHRDLAARNVLLSQ---SLACKICDFGLARSIENEDYETTATK 529
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
LP+KWM PE+ ++T+K+DVWSFGV +WE+FSLG PY N +++ L++ G RL
Sbjct: 530 --LPVKWMAPESLGYRIYTSKSDVWSFGVTMWEIFSLGGTPYVKHRNVDILSLLADGYRL 587
Query: 1093 EKP 1095
KP
Sbjct: 588 PKP 590
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; n=1;
Suberites domuncula|Rep: Bruton's tyrosine kinase-like
protein - Suberites domuncula (Sponge)
Length = 700
Score = 173 bits (422), Expect = 2e-41
Identities = 97/242 (40%), Positives = 137/242 (56%), Gaps = 17/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + SL L K LG G FG V G ++ ++ VA+K + E + E DF+ EA
Sbjct: 427 EIDKVSLSLGKELGSGQFGRVVSGKWK------GKIDVAIKMMREGAMN--EDDFIEEAK 478
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +F H N+V L GVC P FIV EL+ G L FLR+ + E+ + L
Sbjct: 479 VMKQFQHENLVKLYGVCTKNGPIFIVQELMVNGCLLQFLRQRKELVEKTEII-----LDM 533
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ +C +YLE FIHRD+AARNCL+ R VVK+ADFG+AR + +Y G
Sbjct: 534 ATQICSAMKYLEESGFIHRDLAARNCLVGERN---VVKVADFGLARFVVDDEYTASEG-T 589
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE F++K+DVWSFG+LLWE+++ G PY N +V++ V G RL+
Sbjct: 590 KFPIKWAAPEVITHAKFSSKSDVWSFGILLWELWTGGKTPYPTFTNSQVLDEVLMGYRLD 649
Query: 1094 KP 1095
+P
Sbjct: 650 RP 651
>UniRef50_UPI0000F2DD16 Cluster: PREDICTED: similar to cellular-ros
protein (c-ros); n=1; Monodelphis domestica|Rep:
PREDICTED: similar to cellular-ros protein (c-ros) -
Monodelphis domestica
Length = 636
Score = 173 bits (421), Expect = 2e-41
Identities = 78/166 (46%), Positives = 116/166 (69%), Gaps = 3/166 (1%)
Query: 895 TLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRE 954
TL + +T +S+FL EA +M+ F+H +I+ L GVC P+F++LEL+ G DL +FLR
Sbjct: 94 TLRKGATDLEKSEFLKEACLMSHFDHPHIIKLWGVCLQNEPQFLLLELMEGKDLLSFLRG 153
Query: 955 SRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSR---GPGRVVK 1011
+R + L + DL+ +DV +GC YLE F+HRD+AARNCL++ + R VK
Sbjct: 154 ARGTTYQDPLLGIGDLIAICIDVARGCAYLEKMHFVHRDLAARNCLVSVKEYTSHSRKVK 213
Query: 1012 IADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVW 1057
I DFG+ARDIY+ DYY++ G+++LP++WM PE+ +DGVFT ++DVW
Sbjct: 214 IGDFGLARDIYKNDYYREEGESLLPVRWMAPESLLDGVFTNQSDVW 259
>UniRef50_Q4SQ93 Cluster: Tyrosine-protein kinase receptor; n=2;
Tetraodontidae|Rep: Tyrosine-protein kinase receptor -
Tetraodon nigroviridis (Green puffer)
Length = 822
Score = 173 bits (421), Expect = 2e-41
Identities = 101/283 (35%), Positives = 148/283 (52%), Gaps = 25/283 (8%)
Query: 834 NPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAV 893
NP Y S D + + R ++ L + LG+GAFG+V+ + + D ++ VAV
Sbjct: 497 NPQYFRNSISMLKSDTF-VQHIKRHNIILKRELGEGAFGKVFLAECYNLTPDQEKIHVAV 555
Query: 894 K-------------TLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVL 940
K + PE S + L + H +IV GVC + P +V
Sbjct: 556 KVGTGRFSPPSLPPSDPERSQREQPGGLLPGGRAPHQLQHEHIVTFYGVCVESDPLIMVF 615
Query: 941 ELLAGGDLKNFLRESRP--------KPERASALTMKDLLLCSVDVCKGCRYLETKRFIHR 992
E + GDL FLR P + LT +L + + G YL ++ F+HR
Sbjct: 616 EYMKHGDLNKFLRSHGPDAVLIVDGQHSIPVELTQSQMLHIAQQIAAGMVYLASQHFVHR 675
Query: 993 DIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTT 1052
D+A RNCL+ G +VKI DFGM+RD+Y DYY+ GG MLPI+WMPPE+ + FTT
Sbjct: 676 DLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRRFTT 732
Query: 1053 KTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
++DVWS GV+LWE+F+ G P+ +N EV+E ++ G L++P
Sbjct: 733 ESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRP 775
>UniRef50_Q4RJ67 Cluster: Chromosome 1 SCAF15039, whole genome shotgun
sequence; n=2; Tetraodontidae|Rep: Chromosome 1
SCAF15039, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 978
Score = 173 bits (421), Expect = 2e-41
Identities = 103/266 (38%), Positives = 147/266 (55%), Gaps = 19/266 (7%)
Query: 853 PQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
P + E +K +G+G FG+V + + + D +M A+K L E ++ DF E
Sbjct: 672 PILEWEDIKFEDVIGEGNFGQVIKAMVKK---DGNKMSAAIKMLKEFASENDHRDFAGEL 728
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESR---------PKPERA 962
++ K H NI++LIG C +R +I +E G+L +FLR+SR + A
Sbjct: 729 EVLCKLGQHPNIINLIGACENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAKEHGTA 788
Query: 963 SALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
S LT + LL +VDV G YL K+FIHRD+AARN L+ G V KIADFG++R
Sbjct: 789 STLTSQQLLQFAVDVATGMHYLSDKQFIHRDLAARNVLV---GDNLVAKIADFGLSRG-- 843
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
+ Y K LP++WM E+ V+TTK+DVWSFGVLLWE+ SLG PY G E+
Sbjct: 844 -EEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAEL 902
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKRR 1108
E + G R+EKP E ++ ++
Sbjct: 903 YEKLPQGFRMEKPKNCDDEVYELMKQ 928
>UniRef50_Q9BLY1 Cluster: Receptor tyrosine kinase; n=5;
Caenorhabditis|Rep: Receptor tyrosine kinase -
Caenorhabditis elegans
Length = 928
Score = 173 bits (421), Expect = 2e-41
Identities = 89/246 (36%), Positives = 135/246 (54%), Gaps = 6/246 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++ L + + +G+G FG V+ G+Y M VAVK +T + E
Sbjct: 584 EITPSQLSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIR 643
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPER-ASALTMK--DL 970
+A F+H N++ LIGVC+ + V E + GDL L+ P + +T +
Sbjct: 644 AVATFDHPNVIKLIGVCYMDNSLLAVFEYMVHGDLHELLKVRVPPADHDMGGITEANAEF 703
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
L + + G YL + F+HRD+A RNCL+ G R +KIADFG+ R Y +DYYK
Sbjct: 704 LYIATQIALGMEYLASMSFVHRDLATRNCLV---GDTRTIKIADFGLMRTSYGSDYYKML 760
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
++ +P++WM EA G F+ +DVWSFGV LWE++S G PY G +N++V+ELV+
Sbjct: 761 HRSWMPVRWMSKEAIEQGRFSEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANRH 820
Query: 1091 RLEKPY 1096
LE P+
Sbjct: 821 LLECPH 826
>UniRef50_Q7YZW6 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 276
Score = 173 bits (421), Expect = 2e-41
Identities = 88/231 (38%), Positives = 142/231 (61%), Gaps = 10/231 (4%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN-HANIV 924
LG+GAFG+V++G+ R + +PVAVK L + + +F+ E +M H NIV
Sbjct: 3 LGEGAFGQVFKGILRGPNGQV--IPVAVKQLKANAIDEEREEFVREIQMMQTVGQHDNIV 60
Query: 925 HLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYL 984
+ G C D + +++E + GDLK++L+ R + + SA+ K+ L + + G +L
Sbjct: 61 TMYGYCMDEQLQCMIMEYVPYGDLKHYLQNMRKEKDSDSAIDSKEFLSFTNQIACGMAHL 120
Query: 985 ETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEA 1044
E+ IHRD+AARN L+ G G+V+KI+DFGM+R Y K K ++P++W+ PEA
Sbjct: 121 ESVGIIHRDLAARNILV---GTGKVLKISDFGMSRP----GVYIKMSKGVIPLRWLSPEA 173
Query: 1045 YIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
D ++ K+DVW+FGVLLWE+ +LG PY A+++++ ++ G RLE+P
Sbjct: 174 IKDNTYSNKSDVWAFGVLLWEIATLGGFPYNNVADKDILNQLTEGMRLEQP 224
>UniRef50_Q70W12 Cluster: Discoidin receptor; n=1; Ciona
intestinalis|Rep: Discoidin receptor - Ciona intestinalis
(Transparent sea squirt)
Length = 457
Score = 173 bits (421), Expect = 2e-41
Identities = 96/252 (38%), Positives = 149/252 (59%), Gaps = 23/252 (9%)
Query: 853 PQVSRESLKLVKALGQGAFGEV-----YQGLYRHRSAD---AAEMP----VAVKTLPELS 900
P+ RE L++V+ LG+G FGEV + L + SA + E+ VAVK L +
Sbjct: 132 PEFPREKLEVVEQLGEGQFGEVQLCKAHNSLRKLVSAPFQFSGELDEPVLVAVKVLRADA 191
Query: 901 TGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRE------ 954
T A+ DFL E +M++ NIVHLI VC + P ++ E + GDL +LR
Sbjct: 192 TSNAKEDFLKEVRVMSQMQDPNIVHLIAVCTNDEPYAMITEYMENGDLNQYLRSCADKMN 251
Query: 955 SRPKPERASALTMKDLLL-CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIA 1013
S P + S + ++L+ V + G RYL + +F+HRD+A RNCL+ S ++IA
Sbjct: 252 SDPSSKENSLFSSNEVLINMCVQIASGMRYLSSHKFVHRDLATRNCLVDSN---HSIRIA 308
Query: 1014 DFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL-GVM 1072
DFGM+R++Y++DYY+ G+A+LPI+WM E + G F++ +D W+FGV LWE+FS +
Sbjct: 309 DFGMSRNMYQSDYYRIQGRAVLPIRWMSWECVLMGKFSSASDAWAFGVTLWEIFSFCKLQ 368
Query: 1073 PYTGCANREVME 1084
P+ +++V+E
Sbjct: 369 PHNSLTDQQVIE 380
>UniRef50_A7RNB1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 280
Score = 173 bits (421), Expect = 2e-41
Identities = 99/251 (39%), Positives = 139/251 (55%), Gaps = 16/251 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R+ + L LG+G FG V +G + A VA+K L + D L E
Sbjct: 2 EIPRDRVVLKDKLGEGEFGIVMEG--ELLIEEEAPRKVAIKMLKSDADRTDHKDMLRELD 59
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESR------PKPERASALT 966
+ H N+V LIG C P +I+ E +AGG L LRESR S L+
Sbjct: 60 MFKGIGQHENVVSLIGACTLGMPLYIITEFIAGGTLLELLRESRCITSSYVNANLVSKLS 119
Query: 967 MKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADY 1026
KDLL ++ +G R++ RF+HRD+A RN L+T KI DFG++RDIY
Sbjct: 120 GKDLLKLALGAARGMRHISGNRFVHRDLATRNVLVTE---DLTAKITDFGLSRDIYSDGI 176
Query: 1027 Y--KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVME 1084
Y KGGK LP+KWM PE+ +D V+TT++D+WSFGVL+WEV+S G MPY+ E++
Sbjct: 177 YLNAKGGK--LPLKWMAPESLLDYVYTTQSDIWSFGVLMWEVWSFGAMPYSAVVPNELLS 234
Query: 1085 LVSGGGRLEKP 1095
++ G RL +P
Sbjct: 235 MLMSGFRLSRP 245
>UniRef50_A7RHT9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 295
Score = 173 bits (421), Expect = 2e-41
Identities = 93/250 (37%), Positives = 140/250 (56%), Gaps = 14/250 (5%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R+ +K LG GAFG V + + +PVAVK + E + A D + E ++
Sbjct: 6 RDRVKTSVVLGSGAFGVVMKADAQGIKGCVGSLPVAVKIVKENDSDTARRDLMAELDLLK 65
Query: 917 KFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPER---------ASALT 966
+ H N++ L+G C P +++E GDL+++LR R ++ LT
Sbjct: 66 LIDPHPNVIGLLGCCTRGDPLMVIVEFCQYGDLQSYLRHCRGIEDKYYEQIYMVPEKKLT 125
Query: 967 MKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADY 1026
KDLL + +G +L + + +HRD+AARN L+ + V K++DFG ARDIY D+
Sbjct: 126 AKDLLSFGIQAARGMAHLASMKVVHRDLAARNILIDEKS---VCKVSDFGFARDIYVEDH 182
Query: 1027 Y-KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMEL 1085
Y +K PIKWM E+ +DGV TTK+DVWS+GVLLWE+ +LG PY G ++EV+
Sbjct: 183 YTRKTQGGRFPIKWMAIESLLDGVSTTKSDVWSYGVLLWEIVTLGASPYPGMNSQEVINF 242
Query: 1086 VSGGGRLEKP 1095
+ G R++KP
Sbjct: 243 LQDGYRMDKP 252
>UniRef50_UPI0000E4736E Cluster: PREDICTED: similar to src-family
protein tyrosine kinase; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to src-family protein
tyrosine kinase - Strongylocentrotus purpuratus
Length = 387
Score = 173 bits (420), Expect = 3e-41
Identities = 101/242 (41%), Positives = 140/242 (57%), Gaps = 18/242 (7%)
Query: 854 QVSRESL-KLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
+ R+SL ++ + LG+G FGEV+QG++ + PVAVKTL E + A FL EA
Sbjct: 119 ETPRKSLGQMNRRLGEGKFGEVWQGVWNGNT------PVAVKTLKERTMSPAA--FLAEA 170
Query: 913 AIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLL 972
+M K H IV L VC D+ P +IV EL++ GDL+ +L+ + K + M L+
Sbjct: 171 NVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTK-----MTTLID 225
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK 1032
+ G YL +K +HRD+AARN L+ G G VVKIADFG A+ + D Y
Sbjct: 226 MGAHIASGMDYLGSKNVVHRDLAARNVLV---GKGNVVKIADFGRAQ-LMEKDVYVGEEG 281
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
A LP+KW PEA + G FT K+DVWSFG+L+ E+ + G PY REV + V+ G R+
Sbjct: 282 AKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGYPYKKMRTREVTKKVANGYRM 341
Query: 1093 EK 1094
K
Sbjct: 342 PK 343
>UniRef50_Q4RPK6 Cluster: Chromosome 12 SCAF15007, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 12
SCAF15007, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 878
Score = 173 bits (420), Expect = 3e-41
Identities = 110/290 (37%), Positives = 160/290 (55%), Gaps = 28/290 (9%)
Query: 812 EVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAF 871
E + RL+ G N A+ P +S + I P R+ L + LG+G F
Sbjct: 550 ETDIVRLQGVTGSNMYAV-----PALTVDSLTRKDISAAEFP---RQQLIFREKLGEGQF 601
Query: 872 GEVY----QGLYRHRSA-------DAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNH 920
GEV+ +GL D + VAVK L +T QA +DFL E IM++ N
Sbjct: 602 GEVHLCEAEGLPEFLGEGSPLPERDGHSVLVAVKQLRADATSQARNDFLKEIKIMSRLND 661
Query: 921 ANIVHLIGVCFDRHPRFIVLELLAGGDLKNFL--RESRPKPERAS---ALTMKDLLLCSV 975
NI+ L+ VC P +V E + GDL FL RE A+ ++++ DLL +V
Sbjct: 662 PNIIRLLCVCVSSDPLCMVTEYMENGDLNMFLSQREIESTLTHANNIPSVSLSDLLHMAV 721
Query: 976 DVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAML 1035
+ G +YL + F+HRD+A RNCLL R +KIADFGM+R++Y +DYY+ G+A+L
Sbjct: 722 QISSGMKYLASLNFVHRDLATRNCLLDRR---LTIKIADFGMSRNLYSSDYYRIQGRAVL 778
Query: 1036 PIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL-GVMPYTGCANREVME 1084
PI+WM E+ + G FTT +DVW+FGV LWE+F+L PY+ ++ +V+E
Sbjct: 779 PIRWMAWESILLGKFTTASDVWAFGVTLWEIFTLCKEQPYSLLSDEQVIE 828
>UniRef50_P79950 Cluster: Tyrosine kinase receptor; n=3; Xenopus|Rep:
Tyrosine kinase receptor - Xenopus laevis (African clawed
frog)
Length = 1369
Score = 173 bits (420), Expect = 3e-41
Identities = 91/235 (38%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G Y D E+ AVK+L ++ + +FL E +M F+H N+
Sbjct: 1061 RIIGKGHFGSVYHGTYVDE--DQQEVHCAVKSLNRITDLEEVEEFLREGILMKSFHHPNV 1118
Query: 924 VHLIGVCFDRHPR-FIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ LIG+C + +VL + GDL++F+R P T+KDL+ + V +G
Sbjct: 1119 LSLIGICLPQEGLPLVVLPFMKHGDLRHFIRSEERNP------TVKDLVGFGLQVSRGME 1172
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY--KKGGKAMLPIKWM 1040
YL ++F+HRD+AARNC+L VK+ADFG+ARD++ +YY ++ A LP+KWM
Sbjct: 1173 YLANRKFVHRDLAARNCMLDESFH---VKVADFGLARDVFDKEYYSVRRHKNARLPVKWM 1229
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGVLLWE+ + G PY ++ + G RL +P
Sbjct: 1230 AMESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVDAYDITRYLFRGRRLAQP 1284
>UniRef50_Q7PWP1 Cluster: ENSANGP00000013218; n=2; Culicidae|Rep:
ENSANGP00000013218 - Anopheles gambiae str. PEST
Length = 861
Score = 173 bits (420), Expect = 3e-41
Identities = 96/258 (37%), Positives = 137/258 (53%), Gaps = 10/258 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +L L LG+G FG+V +G VAVK L + L E ++
Sbjct: 484 RTNLILDATLGEGEFGKVLKGFATDLPEKPGITTVAVKMLKTGANSVELLALLSEYQLLQ 543
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP------ERA-SALTMKD 969
+ NH N++ L+G C +++E G LKN+LR SR E A +T+KD
Sbjct: 544 EVNHPNVIRLLGACTKGDSPLLIIEYCQYGSLKNYLRLSRKLEVLNADYENAVEPITVKD 603
Query: 970 LLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKK 1029
+L + + KG YL + +HRD+AARN LL G+V KI+DFG+ RD+Y D Y K
Sbjct: 604 ILSFAWQISKGMAYLTDIKLVHRDLAARNVLLAE---GKVCKISDFGLTRDVYEDDAYLK 660
Query: 1030 GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGG 1089
K +P+KWM PE+ D ++TTK+DVW+FGVL WE+ +LG PY G + + L+ G
Sbjct: 661 KSKDRVPVKWMAPESLADHIYTTKSDVWAFGVLCWELITLGASPYPGIPPQNLYNLLKQG 720
Query: 1090 GRLEKPYGEGSEYHKFKR 1107
R+E P E + R
Sbjct: 721 YRMECPKNCSEEIYGIVR 738
>UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF7099, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1000
Score = 172 bits (419), Expect = 4e-41
Identities = 103/277 (37%), Positives = 146/277 (52%), Gaps = 41/277 (14%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q + VAVK L E ++ ++DF EAA+MA
Sbjct: 691 RNNIQYVRDIGEGAFGRVFQARAPGLLPMESFTMVAVKMLKEEASADMQNDFQREAALMA 750
Query: 917 KFNHANIVHLIG--------------------VCFDRHPRFIVLELLAGGDLKNFLRESR 956
+F+H NIV L+G VC P ++ E +A GDL FLR
Sbjct: 751 QFDHPNIVKLLGASFQAVNYGCGCACVCPLTGVCAVGKPMCLMFEYMAHGDLNEFLRRRS 810
Query: 957 PKPE------------------RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARN 998
P A L+ D L S + G YL ++F+HRD+A RN
Sbjct: 811 PDQSVRTISRASLSGRSFTSELEAGLLSCADQLSISKQIAAGMAYLSERKFVHRDLATRN 870
Query: 999 CLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWS 1058
CL+ G VVKIADFG++R+IY ADYYK +PI+WMPPE+ +TT++D+W+
Sbjct: 871 CLV---GEEMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDIWA 927
Query: 1059 FGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+GV+LWE+FS G+ PY G + EV+ V G L P
Sbjct: 928 YGVVLWEIFSHGMQPYYGMGHEEVIYYVRDGHILSCP 964
>UniRef50_UPI0000D57178 Cluster: PREDICTED: similar to CG14396-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG14396-PA, isoform A - Tribolium castaneum
Length = 1065
Score = 172 bits (418), Expect = 5e-41
Identities = 95/260 (36%), Positives = 145/260 (55%), Gaps = 24/260 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R L + + LG+G FG+V + + S VAVKTL + + +D L E ++
Sbjct: 740 RNRLIIEQTLGEGEFGKVLRAKALNISGQPGLTTVAVKTLKDDARESELNDLLSEYQLLK 799
Query: 917 KFNHANIVHLIGVCF-DRHPRFIVLELLAGGDLKNFLRESRP-KPE-------------- 960
+ +H N++ L+GVC P ++++E G L+N+LR SR K E
Sbjct: 800 EVSHPNVIRLLGVCTAPGGPIYLIIEFAEHGSLRNYLRRSRHLKSECGRLPSSTVDENDV 859
Query: 961 -----RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
S +T K++L + +CKG YL + +HRD+AARN LL + ++ KI+DF
Sbjct: 860 HYDEPNISKVTPKEILSFAWQICKGMAYLSEIKLVHRDLAARNVLLAA---DQICKISDF 916
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
G+ RDIY D Y K K +P+KWM PE+ D ++T K+DVWSFG+L+WE+ +LG PY
Sbjct: 917 GLTRDIYEDDAYFKRSKGRVPVKWMAPESLSDHIYTNKSDVWSFGILVWELVTLGATPYP 976
Query: 1076 GCANREVMELVSGGGRLEKP 1095
G A + + L+ G R+E+P
Sbjct: 977 GIAVQNLFHLLRQGYRMERP 996
>UniRef50_Q8WRF4 Cluster: Receptor tyrosine kinase; n=1; Monosiga
brevicollis|Rep: Receptor tyrosine kinase - Monosiga
brevicollis
Length = 1476
Score = 172 bits (418), Expect = 5e-41
Identities = 93/255 (36%), Positives = 139/255 (54%), Gaps = 7/255 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+ ++L + LG GAFGEV+Q R+ S A KTL + + DFL E
Sbjct: 720 EVDRQCVRLGEELGHGAFGEVFQAWIRN-SYSGKVRRCAAKTLKPDVSFEHRQDFLSEMT 778
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLL 972
+M + H N++ +IG C P+ +++EL G+++++LR R E + + +
Sbjct: 779 VMKEIGAHPNVIGIIGHCLRETPQILLVELAEFGNMRDYLRGCRATQENPQTIRVDQMAD 838
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK 1032
+ + +G +LE K IHRD+AARN L+ KI+DFG+AR I +Y K
Sbjct: 839 FCLQIARGMAFLEQKNVIHRDLAARNVLVDKNFE---CKISDFGLARSIEGGEYKTTATK 895
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
LP+KWM PE+ ++TTK+DVWSFGV +WE+FSLG PY NR+V+ + G RL
Sbjct: 896 --LPVKWMAPESLKSRIYTTKSDVWSFGVTMWEIFSLGGTPYKEHQNRDVLSFLESGHRL 953
Query: 1093 EKPYGEGSEYHKFKR 1107
P E+ R
Sbjct: 954 PSPRQAPVEFDDIAR 968
>UniRef50_P08581 Cluster: Hepatocyte growth factor receptor precursor;
n=81; Tetrapoda|Rep: Hepatocyte growth factor receptor
precursor - Homo sapiens (Human)
Length = 1390
Score = 171 bits (417), Expect = 7e-41
Identities = 94/235 (40%), Positives = 135/235 (57%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G D ++ AVK+L ++ S FL E IM F+H N+
Sbjct: 1082 EVIGRGHFGCVYHGTLLDN--DGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query: 924 VHLIGVCF-DRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+G+C +VL + GDL+NF+R P T+KDL+ + V KG +
Sbjct: 1140 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNP------TVKDLIGFGLQVAKGMK 1193
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK--AMLPIKWM 1040
YL +K+F+HRD+AARNC+L + VK+ADFG+ARD+Y +YY K A LP+KWM
Sbjct: 1194 YLASKKFVHRDLAARNCMLDEKF---TVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM 1250
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGV+LWE+ + G PY ++ + G RL +P
Sbjct: 1251 ALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP 1305
>UniRef50_Q14289 Cluster: Protein tyrosine kinase 2 beta; n=47;
Euteleostomi|Rep: Protein tyrosine kinase 2 beta - Homo
sapiens (Human)
Length = 1009
Score = 171 bits (417), Expect = 7e-41
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 414 GGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 471
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 472 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 524
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 525 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 581
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 582 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 640
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 641 GDRLPKP 647
>UniRef50_Q0P4R9 Cluster: Discoidin domain receptor family, member 2;
n=2; Tetrapoda|Rep: Discoidin domain receptor family,
member 2 - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 879
Score = 171 bits (416), Expect = 9e-41
Identities = 96/243 (39%), Positives = 143/243 (58%), Gaps = 18/243 (7%)
Query: 857 RESLKLVKALGQGAFGEVY----QGLYRHRSADAAEMP-----VAVKTLPELSTGQAESD 907
R L+L + LG+G FGEV+ +GL E VAVK L T A +D
Sbjct: 582 RNQLRLKEKLGEGQFGEVHLCEAEGLQEFLEMSPNEFSDQPNMVAVKMLRPDVTKTARND 641
Query: 908 FLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFL--RESRPKPERAS-- 963
FL E I+++ H NI+ L+GVC P ++ E + GDL FL RE R + +A+
Sbjct: 642 FLKEIKIISRLKHPNIIRLLGVCVRDDPLCMITEYMENGDLNQFLSQREIRSQFTKANNI 701
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+++ ++LL + + G +YL + F+HRD+A RNCL+ G +K+ADFGM+R++Y
Sbjct: 702 PSVSRQNLLYMAAQIAAGMKYLASLNFVHRDLATRNCLV---GNSYTIKVADFGMSRNLY 758
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL-GVMPYTGCANRE 1081
DYY+ G+A+LPI+WM E+ + G FTT +D W+FGV LWE+FSL PY+ + +
Sbjct: 759 SGDYYRIQGRAVLPIRWMAWESILLGKFTTCSDAWAFGVTLWEMFSLCKEQPYSVLTDEQ 818
Query: 1082 VME 1084
V+E
Sbjct: 819 VIE 821
>UniRef50_Q5MCM8 Cluster: Protein-tyrosine kinase; n=2;
Anthomedusae|Rep: Protein-tyrosine kinase - Hydractinia
echinata (Snail fur) (Hermit crab hydroid)
Length = 1162
Score = 171 bits (416), Expect = 9e-41
Identities = 95/247 (38%), Positives = 143/247 (57%), Gaps = 16/247 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-----ELSTGQAESDF 908
+V+R+ L L + +GQG FG+VYQG ++ + + + E+PVAVKT E G F
Sbjct: 423 EVARDDLTLDEIIGQGQFGDVYQGTFKSKIS-SVEIPVAVKTYKIELDKEQEDGTRAEKF 481
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
L EA +M +F+H +++ LIG+ D P +I++EL + G+L+++L++ R + E LT
Sbjct: 482 LEEAYLMQQFDHPHVIKLIGIVSDS-PSYIIMELASYGELRSYLQQYRTQTESERLLTYI 540
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L ++ YLE++ F+HRDIAARN L +K+ADFG++R I Y
Sbjct: 541 YQLSTALS------YLESRNFVHRDIAARNILAADP---HTIKLADFGLSRWIDEEQSYY 591
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K K LPIKWM PE+ F++ +DVW FGV WE+ GV P+ G N +V+ +
Sbjct: 592 KASKGKLPIKWMAPESINFRRFSSASDVWMFGVCCWEILMYGVKPFQGVPNEKVIGKIEN 651
Query: 1089 GGRLEKP 1095
G RL P
Sbjct: 652 GERLPLP 658
>UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18;
Euteleostomi|Rep: Tyrosine-protein kinase ITK/TSK - Homo
sapiens (Human)
Length = 620
Score = 171 bits (416), Expect = 9e-41
Identities = 95/241 (39%), Positives = 136/241 (56%), Gaps = 18/241 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ L V+ +G G FG V+ G + ++ VA+KT+ E +E DF+ EA +
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDK------VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M K +H +V L GVC ++ P +V E + G L ++LR R + LL
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMC 463
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+DVC+G YLE IHRD+AARNCL+ G +V+K++DFGM R + Y G
Sbjct: 464 LDVCEGMAYLEEACVIHRDLAARNCLV---GENQVIKVSDFGMTRFVLDDQYTSSTG-TK 519
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
P+KW PE + +++K+DVWSFGVL+WEVFS G +PY +N EV+E +S G RL K
Sbjct: 520 FPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYK 579
Query: 1095 P 1095
P
Sbjct: 580 P 580
>UniRef50_Q16832 Cluster: Discoidin domain-containing receptor 2
precursor; n=54; Euteleostomi|Rep: Discoidin
domain-containing receptor 2 precursor - Homo sapiens
(Human)
Length = 855
Score = 171 bits (416), Expect = 9e-41
Identities = 96/257 (37%), Positives = 145/257 (56%), Gaps = 19/257 (7%)
Query: 843 LPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY----QGLYRHRSAD-----AAEMPV-- 891
L G DV + + R+ L + LG+G FGEV+ +G+ + + D +A PV
Sbjct: 547 LLSGKDV-AVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLV 605
Query: 892 AVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNF 951
AVK L + A +DFL E IM++ NI+HL+ VC P ++ E + GDL F
Sbjct: 606 AVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLSVCITDDPLCMITEYMENGDLNQF 665
Query: 952 LRESRPKPERAS---ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGR 1008
L P +S ++ +L + + G +YL + F+HRD+A RNCL+ G
Sbjct: 666 LSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV---GKNY 722
Query: 1009 VVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFS 1068
+KIADFGM+R++Y DYY+ G+A+LPI+WM E+ + G FTT +DVW+FGV LWE F+
Sbjct: 723 TIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFT 782
Query: 1069 L-GVMPYTGCANREVME 1084
PY+ ++ +V+E
Sbjct: 783 FCQEQPYSQLSDEQVIE 799
>UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -
Caenorhabditis elegans
Length = 533
Score = 170 bits (414), Expect = 2e-40
Identities = 98/245 (40%), Positives = 138/245 (56%), Gaps = 15/245 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R L L + LG G FGEV+ G +R + VA+KT+ T E+ FL EA
Sbjct: 256 EIPRNQLHLKRKLGDGNFGEVWYGKWR------GIVEVAIKTMKP-GTMSPEA-FLQEAQ 307
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM + +H N+V L VC P +I+ E + G L +LR S L ++ L+
Sbjct: 308 IMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTD------GSTLGIQALVDM 361
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPG-RVVKIADFGMARDIYRADYYKKGGK 1032
+ + G YLE ++ +HRD+AARN L+ + G VVK+ADFG+AR + D Y+
Sbjct: 362 AAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTG 421
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
A PIKW PEA G FT K+DVWS+G+LL+E+ + G +PY G NREV+E V G R+
Sbjct: 422 AKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRM 481
Query: 1093 EKPYG 1097
P G
Sbjct: 482 PMPRG 486
>UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4;
Endopterygota|Rep: Tyrosine-protein kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 959
Score = 170 bits (414), Expect = 2e-40
Identities = 96/251 (38%), Positives = 142/251 (56%), Gaps = 15/251 (5%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R L L K+LG+GAFG+V A VAVK L E T D + E +M
Sbjct: 623 RSKLVLGKSLGEGAFGKVVMAEANGLVKGQASTVVAVKMLKEGHTDADVKDLVCEMEVMK 682
Query: 917 KFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESR----------PKPERASAL 965
H NI++L+G C P ++++E G+LK+FLR R + L
Sbjct: 683 MIGKHVNIINLLGCCCKDGPLYVIVEYAPHGNLKDFLRSHRFGTANYEDMISGEKEKKIL 742
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
T K+L+ + + +G +L ++R IHRD+AARN L++ G V+KIADFG+ARDI+ +
Sbjct: 743 TQKELISFAYQIARGMEHLASRRCIHRDLAARNVLVSD---GYVMKIADFGLARDIHSQE 799
Query: 1026 YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE-VME 1084
YY+K LPI+WM PE+ + + +++DVWSFGVLLWE+ +LG PY+ + ++E
Sbjct: 800 YYRKTTTGKLPIRWMAPESLEEKFYDSQSDVWSFGVLLWEIMTLGGNPYSSIPTWDNLLE 859
Query: 1085 LVSGGGRLEKP 1095
+ G RLE+P
Sbjct: 860 HLKKGKRLEQP 870
>UniRef50_Q8MY85 Cluster: Fibroblast growth factor receptor 2
precursor; n=3; Dugesia japonica|Rep: Fibroblast growth
factor receptor 2 precursor - Dugesia japonica
(Planarian)
Length = 887
Score = 170 bits (414), Expect = 2e-40
Identities = 96/260 (36%), Positives = 149/260 (57%), Gaps = 17/260 (6%)
Query: 856 SRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIM 915
SR+SL + +G+GAFG VY L + S ++A + VA+KTL S G + L++ M
Sbjct: 581 SRDSLIIGSKIGEGAFGIVYSALVKSFSENSASVEVAIKTL-HTSFGDQDVINLIQELEM 639
Query: 916 AKF--NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE---------RASA 964
K H +I+ L G C D ++V+EL G+L++FLR R + + +
Sbjct: 640 MKIIGRHRHIISLYGACIDNGHPYMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGLVTR 699
Query: 965 LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRA 1024
LT+ D L S+++ +G YL +++ IHRD+AARN L+ +KIADFG+ R +
Sbjct: 700 LTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVE---MKIADFGLTRIV--E 754
Query: 1025 DYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVME 1084
+YY+K LPIKWM PE +D V+T K+DVWS+G++LWE+F++G PY + + +
Sbjct: 755 NYYRKTTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFTMGQTPYPTIQSDGMHQ 814
Query: 1085 LVSGGGRLEKPYGEGSEYHK 1104
+ G R EKP E ++
Sbjct: 815 ALRNGIRNEKPALASDEMYR 834
>UniRef50_UPI0000E49FB6 Cluster: PREDICTED: similar to RE05926p,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to RE05926p, partial -
Strongylocentrotus purpuratus
Length = 859
Score = 169 bits (412), Expect = 3e-40
Identities = 88/249 (35%), Positives = 142/249 (57%), Gaps = 13/249 (5%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R L L LG G+F +VY+ + VAVK L E +T +SD E ++
Sbjct: 310 RNRLTLFNKLGSGSFADVYKAEAVGIITKEEKTIVAVKRLKETATENDKSDLSKELSLYM 369
Query: 917 KFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP---------KPERASALT 966
+ H NIV+++G C D P +I++E L +L+ +LR+ R ++ +
Sbjct: 370 YLDPHPNIVNILGCCTDSDPWYIIMEYLPNNNLQGYLRQIRTGESMTADYRNVKKQKDIP 429
Query: 967 MKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADY 1026
DLL V + +G YL +++ IHRD+AARN LL G G V K++DFG+ARD+
Sbjct: 430 PNDLLTFGVQIARGMEYLASRQCIHRDLAARNILL---GEGYVCKVSDFGLARDLEDGQT 486
Query: 1027 YKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
Y+ + +P++WM PE+ + +T+++DVWSF +L+WE+ +LG PY G ++++V++ +
Sbjct: 487 YEMKSQGRVPVRWMSPESLLHNTYTSQSDVWSFAILIWEIVTLGSHPYPGMSSKQVVKEI 546
Query: 1087 SGGGRLEKP 1095
S G RL KP
Sbjct: 547 SAGYRLPKP 555
Score = 42.3 bits (95), Expect = 0.071
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R L L+ LG G+F +VY+ + VAVK L + +T +SD E ++
Sbjct: 135 RNRLTLLNKLGSGSFADVYKAEALGIITKEQKTIVAVKRLKDTATENDKSDLSKELSLYM 194
Query: 917 KFN-HANIVHLIGVCFD 932
+ H NIV+++G C D
Sbjct: 195 YLDPHPNIVNILGCCTD 211
>UniRef50_Q64GK4 Cluster: C-Met receptor tyrosine kinase; n=9;
Clupeocephala|Rep: C-Met receptor tyrosine kinase - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 1382
Score = 169 bits (411), Expect = 4e-40
Identities = 94/246 (38%), Positives = 140/246 (56%), Gaps = 16/246 (6%)
Query: 855 VSRESLKLV--KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
++RE L L + +G+G FG V+ G D + A+K+L ++ + S FL E
Sbjct: 1072 IAREDLLLHVNEIIGRGHFGCVFHGTLLE--PDGQKQHCAIKSLNRITDIEEVSQFLKEG 1129
Query: 913 AIMAKFNHANIVHLIGVCFDRHPR-FIVLELLAGGDLKNFLRESRPKPERASALTMKDLL 971
I+ F+H N++ L+G+C +VL + GDL+NF+R+ P T+KDL+
Sbjct: 1130 IIVKDFSHPNVLSLLGICLPSEGSPLVVLPYMKHGDLRNFIRDESHNP------TVKDLM 1183
Query: 972 LCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGG 1031
+ V KG YL +K+F+HRD+AARNC+L VK+AD G+ARD+Y +YY
Sbjct: 1184 GFGLQVAKGMEYLASKKFVHRDLAARNCMLDE---SYTVKVADVGLARDVYDKEYYSVHN 1240
Query: 1032 K--AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGG 1089
K LP+KWM E+ FTTK+DVWSFGVLLWE+ + G PY+ + ++ + G
Sbjct: 1241 KHGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQG 1300
Query: 1090 GRLEKP 1095
RL +P
Sbjct: 1301 RRLLQP 1306
>UniRef50_Q8MY86 Cluster: Fibroblast growth factor receptor 1
precursor; n=2; Dugesia japonica|Rep: Fibroblast growth
factor receptor 1 precursor - Dugesia japonica
(Planarian)
Length = 854
Score = 169 bits (411), Expect = 4e-40
Identities = 90/245 (36%), Positives = 145/245 (59%), Gaps = 11/245 (4%)
Query: 857 RESLKLV-KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIM 915
RE LK+ K LG+GAFG VY+G+ + + VAVK + + + DF+ E IM
Sbjct: 547 REKLKITNKKLGEGAFGMVYEGIANDIGNRSNPIKVAVKMMRDDFSDSNVHDFVKEMEIM 606
Query: 916 AKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL--TMKDLLL 972
H N++ L+G+C + P +++EL G+L++F+R K ++ + +L
Sbjct: 607 KHIGRHPNVIQLLGLCTQKGPLRVIVELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSIL 666
Query: 973 C--SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
C S+ + +G YL ++ +HRD++ARN L+ G +KIADFG+ R + YY+K
Sbjct: 667 CTYSLQIARGMTYLASRSVVHRDLSARNILV---GEHFEMKIADFGLTRIVDY--YYRKK 721
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
+LP+KWM PEA ++ +TTK+DVWS+G+LLWE+F+LG PY+ +V++L+ G
Sbjct: 722 TDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLIRKGF 781
Query: 1091 RLEKP 1095
+ KP
Sbjct: 782 QNPKP 786
>UniRef50_Q9YI66 Cluster: Developmental receptor tyrosine kinase; n=6;
Bilateria|Rep: Developmental receptor tyrosine kinase -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 874
Score = 169 bits (410), Expect = 5e-40
Identities = 91/243 (37%), Positives = 139/243 (57%), Gaps = 13/243 (5%)
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAAIMAKF 918
L L + LG+G FG V + + S + + VAVK L ++++ L EAA M F
Sbjct: 497 LTLGRMLGKGEFGSVREAFLK--SENNSGQKVAVKVLKTDINSSSDIEQCLKEAAYMKDF 554
Query: 919 NHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTMKDLLL 972
+H N++ LIGV R + ++L + GDL FL SR E + ++ + L+
Sbjct: 555 HHPNVIQLIGVSLHRRAQQRLPIPMVILPFMKHGDLHTFLLMSRLGDEPFT-VSQQILIQ 613
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK 1032
+D+ +G YL K IHRD+AARNC+L V +ADFG+++ IY DYY++G
Sbjct: 614 FMLDIARGMEYLSNKNIIHRDLAARNCMLNEN---MSVCVADFGLSKKIYSGDYYRQGSV 670
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
+ LP+KW+ E+ D V+TT++DVW+FGV +WE+ + G PY G N E+ E + G RL
Sbjct: 671 SKLPVKWIALESLADNVYTTQSDVWAFGVTMWEIMTRGQTPYPGVENSEIYEYLIKGERL 730
Query: 1093 EKP 1095
++P
Sbjct: 731 KQP 733
>UniRef50_P21709 Cluster: Ephrin type-A receptor 1 precursor; n=19;
Mammalia|Rep: Ephrin type-A receptor 1 precursor - Homo
sapiens (Human)
Length = 976
Score = 169 bits (410), Expect = 5e-40
Identities = 95/232 (40%), Positives = 129/232 (55%), Gaps = 15/232 (6%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVH 925
+G+G FGEVY+G R S D VA+KTL + S G +FL EA IM +F+H +I+H
Sbjct: 630 IGEGEFGEVYRGTLRLPSQDCKT--VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query: 926 LIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLE 985
L GV R P I+ E + G L FLRE R L L+ + G YL
Sbjct: 688 LEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQLVAMLQGIASGMNYLS 741
Query: 986 TKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGGKAMLPIKWMPPE 1043
++HRD+AARN L+ K++DFG+ R D + Y +GGK +PI+W PE
Sbjct: 742 NHNYVHRDLAARNILVNQN---LCCKVSDFGLTRLLDDFDGTYETQGGK--IPIRWTAPE 796
Query: 1044 AYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
A +FTT +DVWSFG+++WEV S G PY +N+EVM+ + G RL P
Sbjct: 797 AIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPP 848
>UniRef50_Q5RIU8 Cluster: Novel protein similar to vertebrate
discoidin domain receptor family, member 2; n=4; Danio
rerio|Rep: Novel protein similar to vertebrate discoidin
domain receptor family, member 2 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 804
Score = 168 bits (409), Expect = 6e-40
Identities = 98/245 (40%), Positives = 144/245 (58%), Gaps = 20/245 (8%)
Query: 857 RESLKLVKALGQGAFGEVY----QGLYRHRSA-------DAAEMPVAVKTLPELSTGQAE 905
R+ L + LG+G FGEV+ +GL D + VAVK L +T A
Sbjct: 506 RQRLLFREKLGEGQFGEVHLCEAEGLAEFLGEGAPLPEQDGRPVLVAVKQLRADATSNAR 565
Query: 906 SDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFL--RESRPKPERAS 963
+DFL E IM++ N+ NI+ L+ VC P +V E + GDL FL RE A+
Sbjct: 566 NDFLKEIKIMSRLNNPNIIQLLCVCVSSDPLCMVTEYMENGDLNMFLSQREIESTLTHAN 625
Query: 964 ---ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
++++ DLL SV + G +YL + F+HRD+A RNCLL +KI+DFGM+R+
Sbjct: 626 NIPSVSIADLLHMSVQISSGMKYLASLNFVHRDLATRNCLLDRH---LTIKISDFGMSRN 682
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL-GVMPYTGCAN 1079
+Y +DYY+ G+A+LPI+WM E+ + G FTT +DVW+FGV LWE+F+L PY+ ++
Sbjct: 683 LYSSDYYRIQGRAVLPIRWMAWESILLGKFTTASDVWAFGVTLWEIFTLCKEQPYSLLSD 742
Query: 1080 REVME 1084
+V+E
Sbjct: 743 EQVIE 747
>UniRef50_Q06418 Cluster: Tyrosine-protein kinase receptor TYRO3
precursor; n=30; Tetrapoda|Rep: Tyrosine-protein kinase
receptor TYRO3 precursor - Homo sapiens (Human)
Length = 890
Score = 168 bits (409), Expect = 6e-40
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D + + VAVK L ++ +FL EAA
Sbjct: 513 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DGSFVKVAVKMLKADIIASSDIEEFLREAA 570
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 571 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 629
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 630 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 686
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 687 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 746
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 747 GGNRLKQP 754
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 168 bits (409), Expect = 6e-40
Identities = 91/244 (37%), Positives = 141/244 (57%), Gaps = 18/244 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R S++L+K LG G FGEV++GL+ + + PVAVKTL S +DFL EA
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTT------PVAVKTLKPGSMDP--NDFLREAQ 279
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM H ++ L VC P +I+ EL+ G L+ +L+ + S + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQN-----DTGSKIHLTQQVDM 334
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGG 1031
+ V G YLE++ +IHRD+AARN L+ G + K+ADFG+AR + D Y+
Sbjct: 335 AAQVASGMAYLESRNYIHRDLAARNVLV---GEHNIYKVADFGLARVFKVDNEDIYESRH 391
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+ LP+KW PEA F+ K+DVWSFG+LL+E+ + G MPY+G +V+++++ R
Sbjct: 392 EIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYR 451
Query: 1092 LEKP 1095
L +P
Sbjct: 452 LPQP 455
>UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX;
n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein
kinase BMX - Homo sapiens (Human)
Length = 675
Score = 168 bits (409), Expect = 6e-40
Identities = 97/255 (38%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Query: 843 LPQGIDV-RGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELST 901
+P + + G+ ++ RE + L+K LG G FG V G ++ + VAVK + E S
Sbjct: 399 VPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWK------GQYDVAVKMIKEGS- 451
Query: 902 GQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPER 961
+E +F EA M K +H +V GVC +P +IV E ++ G L N+LR
Sbjct: 452 -MSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRS------H 504
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L LL DVC+G +LE+ +FIHRD+AARNCL+ VK++DFGM R +
Sbjct: 505 GKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDR---DLCVKVSDFGMTRYV 561
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
Y G P+KW PE + +++K+DVW+FG+L+WEVFSLG PY N +
Sbjct: 562 LDDQYVSSVG-TKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQ 620
Query: 1082 VMELVSGGGRLEKPY 1096
V+ VS G RL +P+
Sbjct: 621 VVLKVSQGHRLYRPH 635
>UniRef50_Q01974 Cluster: Tyrosine-protein kinase transmembrane
receptor ROR2 precursor; n=36; Euteleostomi|Rep:
Tyrosine-protein kinase transmembrane receptor ROR2
precursor - Homo sapiens (Human)
Length = 943
Score = 168 bits (408), Expect = 8e-40
Identities = 86/244 (35%), Positives = 137/244 (56%), Gaps = 12/244 (4%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
L ++S +++ ++ LG+ FG+VY+G + VA+KTL + + G +F E
Sbjct: 465 LKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHE 524
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
A + A+ H N+V L+GV P ++ + GDL FL P + S
Sbjct: 525 AMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVK 584
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
AL D + + G YL + +H+D+A RN L+ + VKI+D G+ R++Y
Sbjct: 585 SALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDK---LNVKISDLGLFREVY 641
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
ADYYK G ++LPI+WM PEA + G F+ +D+WS+GV+LWEVFS G+ PY G +N++V
Sbjct: 642 AADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDV 701
Query: 1083 MELV 1086
+E++
Sbjct: 702 VEMI 705
>UniRef50_P29317 Cluster: Ephrin type-A receptor 2 precursor; n=32;
Euteleostomi|Rep: Ephrin type-A receptor 2 precursor -
Homo sapiens (Human)
Length = 976
Score = 168 bits (408), Expect = 8e-40
Identities = 97/235 (41%), Positives = 134/235 (57%), Gaps = 15/235 (6%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
K +G G FGEVY+G+ + S+ E+PVA+KTL T + DFL EA IM +F+H NI
Sbjct: 617 KVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNI 675
Query: 924 VHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRY 983
+ L GV P I+ E + G L FLRE K S L + +L + G +Y
Sbjct: 676 IRLEGVISKYKPMMIITEYMENGALDKFLRE---KDGEFSVLQLVGMLR---GIAAGMKY 729
Query: 984 LETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR---DIYRADYYKKGGKAMLPIKWM 1040
L ++HRD+AARN L+ S V K++DFG++R D A Y GGK +PI+W
Sbjct: 730 LANMNYVHRDLAARNILVNSN---LVCKVSDFGLSRVLEDDPEATYTTSGGK--IPIRWT 784
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
PEA FT+ +DVWSFG+++WEV + G PY +N EVM+ ++ G RL P
Sbjct: 785 APEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTP 839
>UniRef50_O16131 Cluster: Insulin receptor homolog precursor; n=2;
Caenorhabditis elegans|Rep: Insulin receptor homolog
precursor - Caenorhabditis elegans
Length = 1846
Score = 167 bits (406), Expect = 1e-39
Identities = 91/252 (36%), Positives = 143/252 (56%), Gaps = 13/252 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEM--PVAVKTLPELSTGQAESDFLME 911
++ ++ + L + G+G+FG+VY G + + + P A+K + ++LME
Sbjct: 1240 ELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLME 1299
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE-RASALTMKDL 970
A IM F IV L GV P +V+E++ G+L+++LR R + D+
Sbjct: 1300 ANIMKNFKTNFIVQLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDI 1359
Query: 971 LL------CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRA 1024
+ + +C G YLE+ +F HRD+AARNC++ VKI DFGMARD++
Sbjct: 1360 IPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINR---DETVKIGDFGMARDLFYH 1416
Query: 1025 DYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVME 1084
DYYK GK M+P++WM PE+ DG F +K+DVWSFGV+L+E+ +LG PY G +N EV+
Sbjct: 1417 DYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLN 1476
Query: 1085 LVSGGGR-LEKP 1095
+ + ++KP
Sbjct: 1477 YIGMARKVIKKP 1488
>UniRef50_UPI00015A61DF Cluster: UPI00015A61DF related cluster; n=2;
Danio rerio|Rep: UPI00015A61DF UniRef100 entry - Danio
rerio
Length = 985
Score = 167 bits (405), Expect = 2e-39
Identities = 96/241 (39%), Positives = 139/241 (57%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+SR + L + LG+G FGEV+ G+Y+ +S + VAVKT + S E F+ EA I
Sbjct: 357 ISRNDIVLGRILGEGFFGEVHDGIYKSKSGERVN--VAVKTCKDCSADVKEK-FMSEALI 413
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M K +H +IV LIG+ + P +IV+EL G+L+N+L++++ K LT L+L S
Sbjct: 414 MKKLDHPHIVRLIGI-IEEDPVWIVMELYPFGELENYLKDNQNK------LTNVTLILYS 466
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+ + K YLE +HRDIA RN L+ VK+ DFG++R I +YYK
Sbjct: 467 LQISKALAYLEGVNMVHRDIAVRNVLVAKVD---CVKLGDFGLSRYIEEEEYYK-ASVTR 522
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
LPIKWM PE+ FT+ +DVW F V +WE+ S G P+ N++V+ + G RL K
Sbjct: 523 LPIKWMAPESINFRRFTSASDVWMFAVCMWEIMSGGQQPFFWLENKDVINQLEQGMRLPK 582
Query: 1095 P 1095
P
Sbjct: 583 P 583
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae|Rep:
Tyrosine-protein kinase - Aedes aegypti (Yellowfever
mosquito)
Length = 747
Score = 166 bits (404), Expect = 3e-39
Identities = 98/256 (38%), Positives = 146/256 (57%), Gaps = 24/256 (9%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ E L+L + +G+G FG+V G+ + VAVK L + G+A + FL EA
Sbjct: 483 EIKMEDLQLKENIGKGEFGDVMLGILKGEK-------VAVKVLKD--AGRASNKFLAEAG 533
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M H N+V IG+ F ++V E ++ G L ++LR SR + +T +D +
Sbjct: 534 VMTTLEHENLVKFIGLVFHDKYIYLVTEYMSKGSLVDYLR-SRGRQH----ITRRDQINF 588
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI-YRADYYKKGGK 1032
+ D C G YLE K+ IHRD+AARN L++ V K++DFG+ARD Y AD K
Sbjct: 589 AFDTCSGMEYLEMKKVIHRDLAARNVLISEEC---VAKVSDFGLARDERYTADISK---- 641
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
LPIKW PEA +G F+ KTD+WSFG+LLWE++S G +PY +V++ V G ++
Sbjct: 642 --LPIKWTAPEALKEGKFSNKTDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVGSGYKM 699
Query: 1093 EKPYGEGSEYHKFKRR 1108
E P G E ++ R+
Sbjct: 700 EAPEGCPPEIYEMMRQ 715
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 166 bits (404), Expect = 3e-39
Identities = 92/244 (37%), Positives = 133/244 (54%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +G+VY+G ++ + +AVK L E +FL EAA
Sbjct: 305 ELDRSEIIMHNKLGGGQYGDVYEGYWKRH-----DCTIAVKALKE--DAMPLHEFLAEAA 357
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +H N+V L+GVC P +I+ E + G+L +LR + S L L+
Sbjct: 358 IMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTDK-----SLLPPIILVQM 412
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + G YLE + FIHRD+AARNCL++ +VKIADFG+AR + D Y A
Sbjct: 413 ASQIASGMSYLEARHFIHRDLAARNCLVSEHN---IVKIADFGLAR-FMKEDTYTAHAGA 468
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE F++K+DVW+FGVLLWE+ + G+ PY G V L+ G R++
Sbjct: 469 KFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLENGFRMD 528
Query: 1094 KPYG 1097
P G
Sbjct: 529 GPQG 532
>UniRef50_Q98TD0 Cluster: Ephrin receptor; n=6; Amniota|Rep: Ephrin
receptor - Gallus gallus (Chicken)
Length = 969
Score = 166 bits (403), Expect = 3e-39
Identities = 94/233 (40%), Positives = 132/233 (56%), Gaps = 16/233 (6%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVH 925
+G+G FGEVY+G R + + VA+KTL + +FL EA IM +FNH NIVH
Sbjct: 622 IGEGEFGEVYRGSLRLPGKE--RIVVAIKTLKSTYSDSQWWNFLREATIMGQFNHPNIVH 679
Query: 926 LIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLE 985
L GV R P I+ E + G L FLRE+ E+ S + + ++L + G YL
Sbjct: 680 LEGVVTKRRPMMIITEYMENGALDTFLRENE---EKFSPVQLVNMLQ---GIASGMTYLS 733
Query: 986 TKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYR---ADYYKKGGKAMLPIKWMPP 1042
++HRD+AARN L+T K++DFG++R + Y KGGK +PI+W P
Sbjct: 734 EHNYVHRDLAARNILVTR---SLQCKVSDFGLSRILENDAEGTYETKGGK--IPIRWTAP 788
Query: 1043 EAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
EA +FT+ +DVWSFG+++WEV S G PY N+EVM+ + G RL P
Sbjct: 789 EAIAHRIFTSASDVWSFGIVMWEVLSFGDKPYGNMTNQEVMKSLEDGYRLPPP 841
>UniRef50_Q95ZV7 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 797
Score = 166 bits (403), Expect = 3e-39
Identities = 93/234 (39%), Positives = 136/234 (58%), Gaps = 19/234 (8%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
LP+++R+ L V +GQG FGEV +R VAVK L +S E F E
Sbjct: 519 LPEIARDKLICVSRIGQGEFGEVDLCQLENRK-------VAVKKLHGISQAD-EFSFHRE 570
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLL 971
++ H N+V ++GVC + P ++E + GDLK+++ ++ + T + +
Sbjct: 571 IRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSYILKN------PTIQTSQCIS 624
Query: 972 LCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGG 1031
+C+ + G YLE+ F+HRDIAARNCL+ G VKIADFGMAR +Y +YYK G
Sbjct: 625 ICT-QLAAGLAYLESCNFVHRDIAARNCLVDGEGN---VKIADFGMARSLYSQEYYKVEG 680
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL-GVMPYTGCANREVME 1084
K +LPI+WM EA + G F+T +DVW FGV +WE+FSL PY+ + +V+E
Sbjct: 681 KFVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVE 734
>UniRef50_Q8WSM2 Cluster: Receptor tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Receptor tyrosine kinase - Schistosoma
mansoni (Blood fluke)
Length = 1559
Score = 166 bits (403), Expect = 3e-39
Identities = 87/233 (37%), Positives = 136/233 (58%), Gaps = 14/233 (6%)
Query: 862 LVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHA 921
L + +GQGAFG VY G + A VAVK + ST + ++DFL EA +M +H
Sbjct: 998 LNRRVGQGAFGMVYGGEAKRNGRWEA---VAVKVIGNKSTYEGKTDFLSEAKLMRSLDHR 1054
Query: 922 NIVHLIGVCF--DRHPRFIVLELLAGGDLKNFLRESRPKPERA---SALTMKDLLLCSVD 976
N+V L+G+C + ++++E + GDLK +L R ++ + L ++D
Sbjct: 1055 NVVRLVGICLYPKENHLYLIMEFMLNGDLKTYLLSRRVLAQQVPDHDGVCPATLTGMAID 1114
Query: 977 VCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD---YYKKGGKA 1033
+ +G YL K IHRDIA RNCL+ S G +VKI DFG+ R++ ++ YY+
Sbjct: 1115 IAEGLAYLHRKNLIHRDIACRNCLVGSDG---IVKIGDFGLTREMNSSENEGYYRFTRNC 1171
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
LPI+WM PEA G+F+ +D+WS+G++L+E+ + GV PY G ++ E++E V
Sbjct: 1172 ELPIRWMSPEAVQFGIFSVHSDIWSYGIVLYEIITFGVFPYDGLSDVEIVERV 1224
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 165 bits (402), Expect = 5e-39
Identities = 104/239 (43%), Positives = 138/239 (57%), Gaps = 21/239 (8%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
RE +K + +G G FG+V++GLYR + VA+KTL ++ G A FL+EA M
Sbjct: 213 REIVKSAQ-IGSGQFGDVFEGLYRGQK-------VAIKTLKDVQ-GDAIDQFLLEADTMT 263
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVD 976
+ H N+V LIGVC P IV E + G L ++LR SR RA L C D
Sbjct: 264 RLRHKNLVQLIGVCTQGSPIMIVSEFMGKGCLLDYLR-SR---GRAVINLATQLGFCR-D 318
Query: 977 VCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLP 1036
+C YLE ++F+HRD+AARN LL+ G V K+ADFG+A+D GK LP
Sbjct: 319 ICAAMEYLEEQKFVHRDLAARNILLSDDG---VAKVADFGLAKDSQLG--VTDIGK--LP 371
Query: 1037 IKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
IKW PEA V T+K+DVWSFGV+LWE+F+ G PY +EV++ V G R+E P
Sbjct: 372 IKWTAPEAIRLKVSTSKSDVWSFGVVLWEIFAFGRAPYPRMGQKEVVDAVVKGYRMECP 430
>UniRef50_Q09147 Cluster: Fibroblast growth factor receptor homolog 2
precursor; n=4; Coelomata|Rep: Fibroblast growth factor
receptor homolog 2 precursor - Drosophila melanogaster
(Fruit fly)
Length = 1052
Score = 165 bits (402), Expect = 5e-39
Identities = 98/262 (37%), Positives = 145/262 (55%), Gaps = 23/262 (8%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRH--RSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L LG+GAFG V RS AE VAVK + E T + + E
Sbjct: 706 EIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVRE 765
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-KPERASA----- 964
+M H NI++L+G C P ++++E G+LK+FL+++RP P+R S
Sbjct: 766 MEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYL 825
Query: 965 ----------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIAD 1014
L K+L + + +G YL ++R IHRD+AARN L++ G V+KIAD
Sbjct: 826 DDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSD---GYVMKIAD 882
Query: 1015 FGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPY 1074
FG+ARDI +YY+K LPIKWM PE+ + + +++DVWS+GVLLWE+ + G PY
Sbjct: 883 FGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPY 942
Query: 1075 TGCAN-REVMELVSGGGRLEKP 1095
+ E+ + G R+EKP
Sbjct: 943 PHILSAEELYSYLITGQRMEKP 964
>UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 -
Tribolium castaneum
Length = 473
Score = 165 bits (401), Expect = 6e-39
Identities = 91/205 (44%), Positives = 124/205 (60%), Gaps = 11/205 (5%)
Query: 891 VAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKN 950
VAVK L E T ++ FL EAAIM KF H +V L GVC + P +IV E ++ G L +
Sbjct: 230 VAVKMLRE-GTMSTQA-FLQEAAIMKKFRHKRLVTLFGVCSEHEPIYIVQEYMSKGSLLD 287
Query: 951 FLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVV 1010
FLR+ K L +DL+ + V G YLE+K+ IHRD+AARN L+ G +
Sbjct: 288 FLRKDEGKE-----LEFEDLVYIAFQVASGMEYLESKQLIHRDLAARNVLI---GENNIA 339
Query: 1011 KIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLG 1070
KI DFG+AR I +Y K G + P+KW PEA + G F+ K+DVWS+G+ L E+F+ G
Sbjct: 340 KICDFGLARVIEDNEYCPKQG-SRFPVKWTAPEAIVYGKFSIKSDVWSYGIFLMELFTYG 398
Query: 1071 VMPYTGCANREVMELVSGGGRLEKP 1095
+PY G REV+++V G R+ KP
Sbjct: 399 QVPYPGMHGREVIDMVEKGYRMGKP 423
>UniRef50_A7SFD8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 229
Score = 165 bits (401), Expect = 6e-39
Identities = 93/209 (44%), Positives = 128/209 (61%), Gaps = 9/209 (4%)
Query: 891 VAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKN 950
VAVK L + S + FL EAAIM +F H N+V++ GV + +P IVLE ++ G+L+N
Sbjct: 3 VAVKMLRDSSDSEDRVKFLQEAAIMRQFTHRNVVYMYGVVTNSNPIMIVLEHMSLGNLRN 62
Query: 951 FLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPG 1007
+L R K + L T LL D+ G +YL + F+HRD+AARN LL S
Sbjct: 63 YLLNLRLKYGKEVVLCLDTRSQLLGMIRDIAAGMQYLHSLGFVHRDLAARNILLDS---D 119
Query: 1008 RVVKIADFGMARDIYRADYY-KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEV 1066
+ KI DFGM+RD+ DYY +GG+ +P+KW PEA G +++ +DVWS+GVLL+E+
Sbjct: 120 MICKIGDFGMSRDLMICDYYTSRGGR--IPVKWTAPEAINYGRYSSASDVWSYGVLLFEI 177
Query: 1067 FSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+SLG PY N EV+E VS G RL P
Sbjct: 178 WSLGDKPYANLDNNEVVEAVSRGYRLPPP 206
>UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1;
Eptatretus burgeri|Rep: TEC family protein tyrosine
kinase - Eptatretus burgeri (Inshore hagfish)
Length = 636
Score = 165 bits (400), Expect = 8e-39
Identities = 100/236 (42%), Positives = 139/236 (58%), Gaps = 18/236 (7%)
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN 919
L ++ LG+GA G V G++R +A++ L E AE DF E +M + +
Sbjct: 378 LTSLRELGRGALGVVQLGMWR------GVRHIAIRMLHEGVL--AEDDFFHEVKLMMQLS 429
Query: 920 HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCK 979
H N+V L GV P IV+E LA G L+ FL ++RP ++ L L CS DVCK
Sbjct: 430 HPNLVQLYGVVTRYRPLRIVMEYLALGCLRTFL-QARPGKLGSAWL----LEACS-DVCK 483
Query: 980 GCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKW 1039
YLE+ F+HRD+AAR+CL+ G +K++DFGMAR + Y G A P+KW
Sbjct: 484 AMVYLESNSFLHRDLAARHCLV---GEDFSIKVSDFGMARYVLDDQYTCSQG-ARFPVKW 539
Query: 1040 MPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
PPE + G F++K+DVWSFGV++WEVFS G +PY G +N EV+E V G +L +P
Sbjct: 540 SPPEVFDRGRFSSKSDVWSFGVVMWEVFSEGTLPYDGWSNGEVVESVHAGYQLPQP 595
>UniRef50_Q4RWP2 Cluster: Tyrosine-protein kinase receptor; n=1;
Tetraodon nigroviridis|Rep: Tyrosine-protein kinase
receptor - Tetraodon nigroviridis (Green puffer)
Length = 1419
Score = 164 bits (399), Expect = 1e-38
Identities = 83/198 (41%), Positives = 117/198 (59%), Gaps = 30/198 (15%)
Query: 924 VHLIGVCFDRHPRFIVLELLAGGDLKNFLR--------------------------ESRP 957
V L+GV P +V+EL+ GDLK++LR +SR
Sbjct: 1101 VRLLGVVSKGQPTLVVMELMTNGDLKSYLRSLRPDAEVAPPHTRHPVCFWVVFFHPQSRN 1160
Query: 958 KPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
P R T+K+++ + ++ G YL K+F+HRD+AARNC++ G VKI DFGM
Sbjct: 1161 NPGRPPP-TLKEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMV---GHDFTVKIGDFGM 1216
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
RDIY DYY+KGGK +LP++WM PE+ DGVFT +D WSFGV+LWE+ +L PY G
Sbjct: 1217 TRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTAHSDCWSFGVVLWEISTLSEQPYQGL 1276
Query: 1078 ANREVMELVSGGGRLEKP 1095
+N +V++ V GG L++P
Sbjct: 1277 SNEQVLKFVMDGGYLDRP 1294
Score = 53.6 bits (123), Expect = 3e-05
Identities = 27/71 (38%), Positives = 43/71 (60%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V RE + +++ LGQG FG VY+GL + E VAVKT+ E + + +FL EA+
Sbjct: 1004 EVPREKISILRELGQGTFGMVYEGLAKDIIKGEGETHVAVKTVNESANLRQRIEFLNEAS 1063
Query: 914 IMAKFNHANIV 924
+M F+ ++V
Sbjct: 1064 VMKAFSCHHVV 1074
>UniRef50_Q70W09 Cluster: Receptor tyrosine kinase VIII; n=1; Ciona
intestinalis|Rep: Receptor tyrosine kinase VIII - Ciona
intestinalis (Transparent sea squirt)
Length = 895
Score = 164 bits (399), Expect = 1e-38
Identities = 93/256 (36%), Positives = 140/256 (54%), Gaps = 19/256 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLY------RHRSADAAEMP--VAVKTLPELSTGQAES 906
+ + LKL K LG+G FG VY+ + S A + VAVK++ E
Sbjct: 537 IENKRLKLGKILGEGEFGFVYKATISADANSNNNSNQTATVQGHVAVKSIKVTGHTYTEV 596
Query: 907 D-FLMEAAIMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKP 959
+ F+ E M +H N++ LIG+ F +VL + GDL+++L R
Sbjct: 597 EGFVKEGLRMKDLDHPNVMALIGIAFTAEDLNKPASPLVVLPYMPNGDLRSYLFSMRTAG 656
Query: 960 ERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
+ T++ LLL ++DV KG +YL + FIHRD+AARNC+L V ++DFG++R
Sbjct: 657 -LSEKFTVQKLLLFALDVAKGMQYLSNRNFIHRDLAARNCMLDENYK---VVVSDFGLSR 712
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
+Y YY++ + +P+KWM E+ D +FT +DVWSFGV +WE+ ++G PY G N
Sbjct: 713 TVYSESYYRQTHISKMPVKWMALESLADNIFTPLSDVWSFGVTVWEILTMGQSPYPGVGN 772
Query: 1080 REVMELVSGGGRLEKP 1095
EV +L+ G RL KP
Sbjct: 773 HEVYQLLRNGTRLNKP 788
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to protein tyrosine kinase - Nasonia vitripennis
Length = 739
Score = 164 bits (398), Expect = 1e-38
Identities = 96/241 (39%), Positives = 135/241 (56%), Gaps = 11/241 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
V E++ L + LG+G FG VY+GL+ S + PVA+K L + +FL EA +
Sbjct: 459 VPGENIILGEVLGEGEFGAVYEGLFD--SPSGTQEPVAIKMLRDTHNIATREEFLREARL 516
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M FNH IV LIG + P +V EL++ G + +L E P+R + +L + +
Sbjct: 517 MMTFNHHCIVKLIGFS-EGPPLLMVQELVSLGSMLAYLLEF---PDRINP--NYELKVWA 570
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+ G +YLE R +HRD+AARN LL S+ KI+DFG++R DYYK
Sbjct: 571 SQIACGMKYLEEIRLVHRDLAARNILLASK---HQAKISDFGLSRTFGSNDYYKATAGGK 627
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
PIKW PE+Y G F+ +DVWS+G+ LWE+FS G PY EV++LV G RL +
Sbjct: 628 WPIKWYAPESYNYGTFSHASDVWSYGITLWEMFSYGEQPYGDRRGTEVIDLVEKGDRLAQ 687
Query: 1095 P 1095
P
Sbjct: 688 P 688
>UniRef50_Q4RY69 Cluster: Chromosome 3 SCAF14978, whole genome shotgun
sequence; n=3; Fungi/Metazoa group|Rep: Chromosome 3
SCAF14978, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 958
Score = 164 bits (398), Expect = 1e-38
Identities = 94/242 (38%), Positives = 140/242 (57%), Gaps = 14/242 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++SR+ + + + LG+G FGEV+ G+Y+ ++ + + VA+KT S E FL EA+
Sbjct: 381 KISRDDIIVGQILGEGFFGEVHNGVYKTQTGE--NLSVAIKTCKNCSADVKEK-FLSEAS 437
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +IV LIGV + P +IV+EL G+L +L E + +LT L+
Sbjct: 438 VMKNLDHPHIVRLIGV-IEADPVWIVMELYEHGELGKYLVEQQ------YSLTTVMLITY 490
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ +CK YLE +HRDIA RN L+ S VK+ DFG++R I +YYK +
Sbjct: 491 CLQICKALAYLEGLNVVHRDIAVRNILVASP---LCVKLGDFGLSRYIEEEEYYKASA-S 546
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LPIKWM PE+ FTT +DVW FGV +WE+FS+ P+ N +V++ + G RL
Sbjct: 547 RLPIKWMAPESINFRRFTTASDVWMFGVCVWEIFSMAQQPFFWLENSQVIDQLESGIRLP 606
Query: 1094 KP 1095
KP
Sbjct: 607 KP 608
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 164 bits (398), Expect = 1e-38
Identities = 91/242 (37%), Positives = 137/242 (56%), Gaps = 11/242 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ +E + K LG+G FG VYQGL R + P+A+K L E + + DFL EA++
Sbjct: 653 IPKECILTQKVLGRGEFGYVYQGLLRPQEPSDCT-PIAIKQLVESTGKRNRVDFLREASV 711
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M + H IV LIG+C P +V EL+ G + +++ ++ + +L++ +
Sbjct: 712 MIRLRHHCIVKLIGIC-KGPPLMMVEELVPLGSMLDYIIANK-----GTINPKLELVIWA 765
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD-YYKKGGKA 1033
+ G +YLE F+HRD+AARN LL SR KI+DFG++R I D YY+
Sbjct: 766 AQIACGMQYLEQHHFVHRDLAARNILLASRNQA---KISDFGLSRAIGAGDDYYRASQGG 822
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE++ G F+ +DVWSFGV +WE++SLG PY +V++L+ G RL
Sbjct: 823 KWPIKWYAPESFNYGTFSHASDVWSFGVTMWEMYSLGAPPYQDMKGVDVIKLIENGQRLS 882
Query: 1094 KP 1095
+P
Sbjct: 883 QP 884
>UniRef50_P23049 Cluster: Tyrosine-protein kinase transforming protein
SEA; n=6; root|Rep: Tyrosine-protein kinase transforming
protein SEA - Avian erythroblastosis virus (strain S13)
Length = 370
Score = 164 bits (398), Expect = 1e-38
Identities = 88/235 (37%), Positives = 133/235 (56%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G Y + AVK+L ++ + +FL E +M F+H +
Sbjct: 64 RVIGRGHFGSVYHGTYMDPLL--GNLHCAVKSLHRITYLEEVEEFLREGILMKGFHHPQV 121
Query: 924 VHLIGVCFDRHPR-FIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+GVC RH +VL + GDL++F+R P T+K+L+ + V G
Sbjct: 122 LSLLGVCLPRHGLPLVVLPYMRHGDLRHFVRAQERSP------TVKELIGFGLQVALGME 175
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY--KKGGKAMLPIKWM 1040
YL K+F+HRD+AARNC+L VK+ADFG+ARD++ +YY ++ A LP++WM
Sbjct: 176 YLAQKKFVHRDLAARNCMLDET---LTVKVADFGLARDVFGKEYYSIRQHRHAKLPVRWM 232
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGVL+WE+ + G PY ++ + G RL +P
Sbjct: 233 ALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLPQP 287
>UniRef50_A7S4Y9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 277
Score = 163 bits (397), Expect = 2e-38
Identities = 87/239 (36%), Positives = 130/239 (54%), Gaps = 7/239 (2%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R L+ ++ LG G++G + E V VK+L E DF E +
Sbjct: 5 RHDLEALRTLGNGSYGRAFLARASGIKDGERETMVVVKSLIAKDDIVRE-DFTRELESLV 63
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVD 976
H+N+V L+GVC D P +++ E GDLK FL R++ + L +CS +
Sbjct: 64 NMEHSNVVSLLGVCRDSEPFYMIFECFEKGDLKQFLLSCNDNG-RSTLTSSHKLTMCS-N 121
Query: 977 VCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLP 1036
+ G YL +F+H+D+AARNC++T VKI ++ D+Y A+YY+ ++P
Sbjct: 122 IVSGMSYLAANKFVHKDLAARNCMVTK---DLQVKIGFLNLSYDLYNAEYYRFNN-ILIP 177
Query: 1037 IKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
++WMP EA FT K+DVWSFGVL WE++SLG +PYT ++ EV++ V RL KP
Sbjct: 178 LRWMPSEAIFHDDFTEKSDVWSFGVLAWEIYSLGQIPYTDRSDEEVLKCVKDDLRLPKP 236
>UniRef50_P35590 Cluster: Tyrosine-protein kinase receptor Tie-1
precursor; n=37; Deuterostomia|Rep: Tyrosine-protein
kinase receptor Tie-1 precursor - Homo sapiens (Human)
Length = 1138
Score = 163 bits (397), Expect = 2e-38
Identities = 99/266 (37%), Positives = 146/266 (54%), Gaps = 19/266 (7%)
Query: 853 PQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
P + E + +G+G FG+V + + + D +M A+K L E ++ DF E
Sbjct: 832 PVLEWEDITFEDLIGEGNFGQVIRAMIKK---DGLKMNAAIKMLKEYASENDHRDFAGEL 888
Query: 913 AIMAKF-NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESR-----PKPER----A 962
++ K +H NI++L+G C +R +I +E G+L +FLR+SR P R A
Sbjct: 889 EVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTA 948
Query: 963 SALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
S L+ + LL + D G +YL K+FIHRD+AARN L+ G KIADFG++R
Sbjct: 949 STLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLV---GENLASKIADFGLSRG-- 1003
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
+ Y K LP++WM E+ V+TTK+DVWSFGVLLWE+ SLG PY G E+
Sbjct: 1004 -EEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAEL 1062
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKRR 1108
E + G R+E+P E ++ R+
Sbjct: 1063 YEKLPQGYRMEQPRNCDDEVYELMRQ 1088
>UniRef50_UPI0000E49AA5 Cluster: PREDICTED: similar to leukocyte
receptor tyrosine protein kinase, partial; n=7;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
leukocyte receptor tyrosine protein kinase, partial -
Strongylocentrotus purpuratus
Length = 899
Score = 163 bits (396), Expect = 2e-38
Identities = 130/435 (29%), Positives = 188/435 (43%), Gaps = 66/435 (15%)
Query: 95 IAIDNIRMIDCVPEPPVYNGECNAGQLKCKIMNRESCIKLHQVCDLVKDCDDGSDEQKN- 153
IA+DNI+++DC P+ + N+ +C N E CI +CDL DC G DE
Sbjct: 165 IALDNIQLLDCSPDHVAPSCSPNS-YFECT--NLE-CIPKENLCDLRPDCLFGEDEDSTV 220
Query: 154 CDKMPYGSYCNFEQDSCGFVD-VPQPILKWSRHRGPTPTDKTGPNYDHTCGPPTQPNLNP 212
C +PYG+ C+FE CG+ + V Q W+RH G T + TGP+ DHT G
Sbjct: 221 CGHIPYGAKCDFESGLCGWYNIVGQDHQNWTRHHGSTKSTGTGPSVDHTLG--------- 271
Query: 213 TKKVPPLTPPFHMHCAGYYFFVNMNVTGPNKEKADFASTAVMKTVIFNPPPKVHGDVASK 272
T++ GYYF+ + G E A M++ +F PP + +
Sbjct: 272 TEE-------------GYYFYYETSGIGTGDE-------AYMRSSVFEAPPATTRNRTNP 311
Query: 273 YYNCCMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFSTKDKGENWYRASIFLPNV- 331
Y C RF Y G +L + + IS+ ++ + W +P+V
Sbjct: 312 MYKACKFRFAYHMYGTEPSTLKIFAIS-AENPEISSQLFSEYNRNIDRWVEIVQPMPDVI 370
Query: 332 TRRYYLQFKTRMGMRIYSDSAIDDFSMSPECFGLN----------VDPEELG----DYNY 377
T RY++Q + G D A+DD S+SPECF N +P G +
Sbjct: 371 TDRYFIQIEATRGRGWKGDVAVDDISLSPECFEKNNTSVGSTAGYTNPWSSGPRTTNMTS 430
Query: 378 Y--------DPVFDEKTTP----HKDFTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPV 425
Y DP TT K+ V + FT CG G YGP Q C AAY T +
Sbjct: 431 YPTPSTVMTDPTNGATTTATTTVKKEPIPTVNFTFTTCGTHGPYGPTQARCTAAYRYTNL 490
Query: 426 DVNVLH---THPYTGVQVWEVPEEGLYTIIATXXXXXXXXXXXXXXHGAQARALLELHRS 482
V VL+ + GVQVW PE LY++ A A+ A+ L
Sbjct: 491 TVRVLNHEDSISLAGVQVWTAPETRLYSVTAYGASGGAGVENSGPSKAAKVDAIFNLTAG 550
Query: 483 ELVYMLIGQQGINAC 497
+ +++L+GQ+G +AC
Sbjct: 551 DQLFILVGQEGESAC 565
Score = 105 bits (251), Expect = 9e-21
Identities = 66/147 (44%), Positives = 90/147 (61%), Gaps = 16/147 (10%)
Query: 797 KKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHY---GSESFLPQGIDVRGLP 853
K+ + + A+ + ME QL +LRN A+ NP Y G +S D++ LP
Sbjct: 766 KEHKLKVAENK-MEASYQLSQLRNN-------FAIDVNPCYTIPGKDSPATSH-DLKELP 816
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
RE+L+L+ ALGQGAFGEV++G+Y+ +E+ +AVKTLPE T Q E DFLMEA
Sbjct: 817 ---RENLRLISALGQGAFGEVFRGVYQPPH-QKSEIDIAVKTLPEHCTEQDELDFLMEAL 872
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVL 940
IM F+H N+V L+G+CF P FIVL
Sbjct: 873 IMGNFDHPNVVSLLGICFKEKPHFIVL 899
>UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 510
Score = 163 bits (396), Expect = 2e-38
Identities = 97/242 (40%), Positives = 136/242 (56%), Gaps = 17/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++S++S+K+VK LG G FGEV+ Y + + VAVKTL T E+ FL EA
Sbjct: 239 EISKDSIKMVKKLGAGQFGEVWMAFYNNSTK------VAVKTLKP-GTMSVEA-FLEEAN 290
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M H +V L V P +I+ E +A G L +FL K + S + + L+
Sbjct: 291 LMKTLQHDRLVRLYAVVTKTEPIYIITEYMANGSLLDFL-----KSQAGSKIQLPKLIDF 345
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
S + +G Y+E K +IHRD+ A N L++ + KIADFG+AR I Y + G A
Sbjct: 346 SAQIAEGMAYIEKKNYIHRDLRAANVLVSEM---LLCKIADFGLARVIEDDQYTAREG-A 401
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PEA G FT K+D+WSFGVLL+E+ + G +PY G +N EVM V G R+
Sbjct: 402 KFPIKWTAPEAINYGSFTIKSDMWSFGVLLYEIITYGKIPYPGMSNSEVMSSVQRGYRMP 461
Query: 1094 KP 1095
+P
Sbjct: 462 RP 463
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 163 bits (395), Expect = 3e-38
Identities = 95/251 (37%), Positives = 147/251 (58%), Gaps = 20/251 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPE-LSTGQAESDFLMEAA 913
+ + SL +G+G FGEV+ G Y + VA+K++ + L +A++ FL EA+
Sbjct: 221 IPKASLLKKSLIGKGEFGEVWLGDYEGKK-------VAMKSMKDHLKDEKAKTQFLAEAS 273
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M H N+V LIG+ D +P +++ E +A G L ++LR SR + + +T ++ +
Sbjct: 274 VMTTLRHPNLVCLIGISLDDNPIYLITEFMAKGSLIDYLR-SRGR----AVITKQNQIDF 328
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ DV KG YLE++ F+HRD+AARN L+ V K++DFG+A+ + K+ G A
Sbjct: 329 ARDVVKGMVYLESQNFVHRDLAARNVLIAE---DNVAKVSDFGLAKS---SSNVKQEG-A 381
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LP+KW PEA + F+ KTDVWSFGVLLWE++S G +PY +V V G R+E
Sbjct: 382 KLPVKWTAPEALRENKFSNKTDVWSFGVLLWEIYSYGRVPYPRVPVEDVANHVENGYRME 441
Query: 1094 KPYGEGSEYHK 1104
P G + +K
Sbjct: 442 SPDGCPDQIYK 452
>UniRef50_A7RGW8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 337
Score = 163 bits (395), Expect = 3e-38
Identities = 94/255 (36%), Positives = 137/255 (53%), Gaps = 16/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLY--RHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
+V S+ + +G GAFG+V + + E VAVK L ++T + +FL E
Sbjct: 12 EVDYSSIAFGEVVGSGAFGKVTKATIVGLPGGPENKETVVAVKKLNAMATMEDRRNFLSE 71
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL----- 965
+M + H NIV ++G ++ E GDL+N+LR R K +L
Sbjct: 72 IEMMKQLGKHLNIVSILGCVTHAGQLCLITEYCPYGDLRNYLRAIRDKVSTRDSLAGRAP 131
Query: 966 ----TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
T DLL + + G YL K F+HRD+AARN L+ +VKI+DFG+ RD+
Sbjct: 132 GRELTQNDLLSFARQIAVGMEYLSQKMFVHRDLAARNILICE---DNLVKISDFGLTRDV 188
Query: 1022 YRA-DYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
Y + +Y+K LP+KWM PEA V TTK+DVW+FGV+LWE+ +LG PY G + +
Sbjct: 189 YESSEYHKMHNTGKLPLKWMAPEAIFQNVHTTKSDVWAFGVVLWEIVTLGGSPYPGQSGK 248
Query: 1081 EVMELVSGGGRLEKP 1095
E + + G R+EKP
Sbjct: 249 EFYKKLKNGYRMEKP 263
>UniRef50_Q95YD4 Cluster: Protein kinase protein 32, isoform a; n=4;
Caenorhabditis|Rep: Protein kinase protein 32, isoform a
- Caenorhabditis elegans
Length = 867
Score = 162 bits (394), Expect = 4e-38
Identities = 93/239 (38%), Positives = 137/239 (57%), Gaps = 14/239 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ RE + L + +G G FG VY+ +Y D + VAVK + L E++
Sbjct: 361 RLRRELITLKELIGGGQFGNVYKAVYHDLEKDE-RIAVAVKVCKTDAEPADTQLILQESS 419
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M F H+NI+ LIGVC D+ P ++VLEL G+L+ +L++ + L ++ L L
Sbjct: 420 LMRNFRHSNIIQLIGVCVDQ-PMWLVLELAPKGELREYLQQEK------DWLPLRILTLF 472
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI-YRADYYKKGGK 1032
+C YL + RF+HRDIAARN L+ S + VK+ADFG++R + Y A Y GK
Sbjct: 473 CSQICDSLVYLHSTRFVHRDIAARNILVCSP---QCVKLADFGLSRALDYDAVYTASRGK 529
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
LPIKW+ PE+ F+ +DVW FGV +WE+FSLGV P+ G N +V+ + G R
Sbjct: 530 --LPIKWLAPESVNYRQFSMASDVWMFGVCMWEIFSLGVKPWAGVTNSDVIMHIEQGSR 586
>UniRef50_Q02763 Cluster: Angiopoietin-1 receptor precursor; n=41;
Euteleostomi|Rep: Angiopoietin-1 receptor precursor -
Homo sapiens (Human)
Length = 1124
Score = 162 bits (394), Expect = 4e-38
Identities = 98/266 (36%), Positives = 142/266 (53%), Gaps = 19/266 (7%)
Query: 853 PQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
P + +K +G+G FG+V + + D M A+K + E ++ DF E
Sbjct: 817 PVLDWNDIKFQDVIGEGNFGQVLKARIKK---DGLRMDAAIKRMKEYASKDDHRDFAGEL 873
Query: 913 AIMAKF-NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESR---PKP------ERA 962
++ K +H NI++L+G C R ++ +E G+L +FLR+SR P A
Sbjct: 874 EVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTA 933
Query: 963 SALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
S L+ + LL + DV +G YL K+FIHRD+AARN L+ G V KIADFG++R
Sbjct: 934 STLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILV---GENYVAKIADFGLSRG-- 988
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
+ Y K LP++WM E+ V+TT +DVWS+GVLLWE+ SLG PY G E+
Sbjct: 989 -QEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAEL 1047
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKRR 1108
E + G RLEKP E + R+
Sbjct: 1048 YEKLPQGYRLEKPLNCDDEVYDLMRQ 1073
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n=11;
Metazoa|Rep: Tyrosine-protein kinase isoform SRK1 -
Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 162 bits (394), Expect = 4e-38
Identities = 96/250 (38%), Positives = 137/250 (54%), Gaps = 18/250 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + +KL++ LG G FGEV++GL+ ++ VAVKTL T E +FL EA+
Sbjct: 234 EIEKTQIKLLRRLGAGQFGEVWEGLWNGTTS------VAVKTLKP-GTMSVE-EFLQEAS 285
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM + H ++ L VC P +IV EL+ G L +LR L ++ L+
Sbjct: 286 IMKRLRHPKLIQLYAVCTKEEPIYIVTELMKYGSLLEYLRGED------GVLKIEQLVDV 339
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ V G YLE + +IHRD+AARN L+ G + K+ADFG+AR I Y G A
Sbjct: 340 AAQVASGMSYLEQQNYIHRDLAARNILVGEHG---ICKVADFGLARVIDEEIYEAHTG-A 395
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PEA + FT K+DVWSFGV+L+E+ + G PY G N EV+E + R+
Sbjct: 396 KFPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITYGRFPYPGMTNPEVLEKIQQNYRMP 455
Query: 1094 KPYGEGSEYH 1103
P ++H
Sbjct: 456 CPANCPKQFH 465
>UniRef50_P04626 Cluster: Receptor tyrosine-protein kinase erbB-2
precursor; n=36; Euteleostomi|Rep: Receptor
tyrosine-protein kinase erbB-2 precursor - Homo sapiens
(Human)
Length = 1255
Score = 162 bits (393), Expect = 6e-38
Identities = 95/238 (39%), Positives = 141/238 (59%), Gaps = 15/238 (6%)
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN 919
L+ VK LG GAFG VY+G++ + ++PVA+K L E ++ +A + L EA +MA
Sbjct: 720 LRKVKVLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVG 778
Query: 920 HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCK 979
+ L+G+C + +V +L+ G L + +RE+R + L +DLL + + K
Sbjct: 779 SPYVSRLLGICLTSTVQ-LVTQLMPYGCLLDHVRENRGR------LGSQDLLNWCMQIAK 831
Query: 980 GCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGGKAMLPI 1037
G YLE R +HRD+AARN L+ S P V KI DFG+AR DI +Y+ GGK +PI
Sbjct: 832 GMSYLEDVRLVHRDLAARNVLVKS--PNHV-KITDFGLARLLDIDETEYHADGGK--VPI 886
Query: 1038 KWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
KWM E+ + FT ++DVWS+GV +WE+ + G PY G RE+ +L+ G RL +P
Sbjct: 887 KWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQP 944
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 161 bits (392), Expect = 7e-38
Identities = 95/255 (37%), Positives = 139/255 (54%), Gaps = 18/255 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+S + + +G G FG+V G Y++R VA+K G +S L EA
Sbjct: 278 ISSNDIDVGDTIGHGEFGDVRLGTYKNRK-------VALKVSKRHGNGMLDS-LLDEAKF 329
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M +H N+V L+GV D +++ E +A G+L + LR SR + AL + L++ +
Sbjct: 330 MVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLR-SRGR----HALERRQLMMFA 384
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+D+C+G YLE+K+ +HRD+AARN LL V K++DFG+A+ + GK
Sbjct: 385 MDICQGMCYLESKQIVHRDLAARNVLLDD---DLVAKVSDFGLAKKANSQSHDSASGK-- 439
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
PIKW PEA FTTK+DVWSFG+LLWE+FS G +PY ++V+ + G R+E
Sbjct: 440 FPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEA 499
Query: 1095 PYGEGSEYHKFKRRT 1109
P G E K T
Sbjct: 500 PEGCPPEIFKVMNET 514
>UniRef50_A7RVU0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 337
Score = 161 bits (392), Expect = 7e-38
Identities = 96/258 (37%), Positives = 144/258 (55%), Gaps = 23/258 (8%)
Query: 858 ESLKLVKALGQGAFGEVYQ----GL--YRHRSADAAEMPVAVKTLPEL-STGQAESDF-- 908
E L L K LGQGAFG+V + G+ + R A + K L G +ESD+
Sbjct: 30 ERLILGKVLGQGAFGQVLRAEAIGMDNFNPRDKSADGLKTRSKMRRSLRGKGASESDYKD 89
Query: 909 -LMEAAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP--KP----- 959
E I+ H NIV+++G C +++E G+L +FLR R +P
Sbjct: 90 LASELKILIHLGEHKNIVNVLGACTRGRRLMVIIEFAPYGNLLSFLRARREVYQPTWTKT 149
Query: 960 --ERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
+ T+ DL + S V +G +L +++ +HRD+AARN L+ GP V+K++DFG+
Sbjct: 150 TNDPEKNYTLVDLTMASYQVSRGVEFLASRKCVHRDLAARNVLV---GPDYVMKVSDFGL 206
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
ARDIY+ D Y K +LP+KWM E+ D V+T K+DVWSFG+LLWE+ +LG PY G
Sbjct: 207 ARDIYQDDLYVKNTSGLLPVKWMALESLFDRVYTEKSDVWSFGILLWEIMTLGGTPYPGL 266
Query: 1078 ANREVMELVSGGGRLEKP 1095
++++ +S G R+ +P
Sbjct: 267 PTEQLLDYLSEGQRMAQP 284
>UniRef50_Q07407 Cluster: Fibroblast growth factor receptor homolog 1
precursor; n=3; Sophophora|Rep: Fibroblast growth factor
receptor homolog 1 precursor - Drosophila melanogaster
(Fruit fly)
Length = 729
Score = 161 bits (392), Expect = 7e-38
Identities = 96/257 (37%), Positives = 142/257 (55%), Gaps = 25/257 (9%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R L L LG+GAFG V A+ VAVK + E T + + E
Sbjct: 410 ELPRSHLVLGATLGEGAFGRVVM-------AEVNNAIVAVKMVKEGHTDDDIASLVREME 462
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPER- 961
+M H NI++L+G C P ++++E G+LK+FL ++RP +P
Sbjct: 463 VMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPS 522
Query: 962 --ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
A +T KDL+ + + +G YL ++R IHRD+AARN L++ V+KIADFG+AR
Sbjct: 523 PPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSD---DYVLKIADFGLAR 579
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPY-TGCA 1078
DI DYY+K LPIKWM PE+ + + +K+DVWS+G+LLWE+ + G PY T +
Sbjct: 580 DIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMS 639
Query: 1079 NREVMELVSGGGRLEKP 1095
E+ + G R+EKP
Sbjct: 640 AEELYTYLMSGQRMEKP 656
>UniRef50_UPI000065F6B2 Cluster: Receptor tyrosine-protein kinase
erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine
kinase-type cell surface receptor HER4).; n=1; Takifugu
rubripes|Rep: Receptor tyrosine-protein kinase erbB-4
precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type
cell surface receptor HER4). - Takifugu rubripes
Length = 1236
Score = 161 bits (391), Expect = 1e-37
Identities = 97/238 (40%), Positives = 139/238 (58%), Gaps = 15/238 (6%)
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN 919
LK VK LG GAFG VY+G++ + ++PVAVK L E + +A +F+ EA IMA
Sbjct: 670 LKRVKVLGSGAFGTVYKGIWVPEG-EKVKIPVAVKILNEATGPKANVEFMDEALIMASME 728
Query: 920 HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCK 979
H ++V L+GVC + +V +L+ G L +++ E K S L LL V + K
Sbjct: 729 HPHLVRLLGVCLSPTIQ-LVTQLMPHGCLLDYVHEH--KDNIGSQL----LLNWCVQIAK 781
Query: 980 GCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGGKAMLPI 1037
G YLE +R +HRD+AARN L+ S P + KI DFG+AR D+ +Y GGK + I
Sbjct: 782 GMMYLEERRLVHRDLAARNVLVKS--PNHI-KITDFGLARLLDVNEKEYNADGGK--MAI 836
Query: 1038 KWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
KWM E FT ++DVWS+GV +WE+ + G PY G + R++ +L+ G RL +P
Sbjct: 837 KWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGISTRDIPDLLEKGERLPQP 894
>UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep:
Tyrosine kinase - Schistosoma mansoni (Blood fluke)
Length = 1264
Score = 161 bits (391), Expect = 1e-37
Identities = 94/243 (38%), Positives = 140/243 (57%), Gaps = 15/243 (6%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTL-PELSTGQAESDFLMEAA 913
++ +++ L + LG G FG V +GLYR S E+PVAVKTL P E + L EA
Sbjct: 883 LNSQTVTLKERLGGGNFGHVVKGLYRTPSGQ--EVPVAVKTLKPNQIANSGEREILAEAR 940
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
MA+ H +IV LIGVC + +VLEL G + +L++ +P+ S T+ +L+
Sbjct: 941 TMAQLKHRHIVRLIGVCKEEQ-FMLVLELAPLGPINKYLKK---RPD-VSVHTLTELMH- 994
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI-YRADYYKKGGK 1032
V G YLE+ +F+HRD+AARN LL +R KI+DFGM++ + + +DYY+
Sbjct: 995 --QVALGMAYLESCKFVHRDLAARNVLLVTR---HFAKISDFGMSKALNFGSDYYRAATA 1049
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
P+KW PE F +K+DVWS+G+ LWEV+S G PY +++ ++ G RL
Sbjct: 1050 GKWPLKWYAPECIYYFRFDSKSDVWSYGITLWEVYSYGERPYRDMKGAQILAMLDQGLRL 1109
Query: 1093 EKP 1095
+P
Sbjct: 1110 SRP 1112
>UniRef50_A1IKE0 Cluster: Receptor tyrosine kinase-like orphan
receptor; n=2; Nematostella vectensis|Rep: Receptor
tyrosine kinase-like orphan receptor - Nematostella
vectensis
Length = 715
Score = 161 bits (391), Expect = 1e-37
Identities = 87/234 (37%), Positives = 127/234 (54%), Gaps = 10/234 (4%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAA-EMPVAVKTLPELSTGQAESDFLMEAAIM 915
+ESL+L+K LG+G +G+VY G +S V V +L E +F +A
Sbjct: 436 KESLRLLKELGEGDYGKVYFGEITTKSEGRLMATSVLVVSLRESHEVDVRDEFFEKAEAW 495
Query: 916 AKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMKD 969
+K H NI+ ++G+C P ++ E L G L +L + P + E A L
Sbjct: 496 SKLQHPNIITIVGMCNKSVPTCVLYEYLEYGTLHEYLVRNAPIDDPEAEEEIADPLWCDG 555
Query: 970 LLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKK 1029
L+ + V G YL + +H D+A RNC++ GPGR VKI D + R Y DYY++
Sbjct: 556 LISIAYQVAAGMNYLSSNNIVHGDLATRNCMV---GPGRTVKITDVALTRLGYSHDYYRQ 612
Query: 1030 GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM 1083
+ LP++WM PEA + FT +TD+WSFGVLLWE+FS G P+ G +N +VM
Sbjct: 613 LHRRPLPVRWMAPEAILSYRFTPETDIWSFGVLLWELFSYGAQPHFGFSNEDVM 666
>UniRef50_Q9YGM5 Cluster: Plasminogen related growth factor receptor
2; n=11; Clupeocephala|Rep: Plasminogen related growth
factor receptor 2 - Fugu rubripes (Japanese pufferfish)
(Takifugu rubripes)
Length = 1375
Score = 161 bits (390), Expect = 1e-37
Identities = 88/235 (37%), Positives = 133/235 (56%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G ++ E AVK+L ++ + FL E IM F+H NI
Sbjct: 1069 QVIGKGHFGTVYHGYLI--DSNKQETHCAVKSLNRITDLKDVDHFLREGLIMKGFDHPNI 1126
Query: 924 VHLIGVCFDRHPR-FIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+G+ + +VL + GD+++F+R + P T+KDL+ + V KG
Sbjct: 1127 LSLLGIMLPKEGLPLVVLPYMKHGDVRHFIRSEKRNP------TVKDLIGFGLQVAKGME 1180
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY--KKGGKAMLPIKWM 1040
YL K+F+HRD+AARNC+L VK+ADFGMARDIY +YY + + LP+KWM
Sbjct: 1181 YLAQKKFVHRDLAARNCMLDET---YTVKVADFGMARDIYDKEYYSIQDHKQVKLPVKWM 1237
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FT+K+DVWS+G+L+WE+ + G PY ++ + G RL +P
Sbjct: 1238 AIESLQTQKFTSKSDVWSYGILMWELLTRGASPYPDVDPYDITNYLLKGRRLPQP 1292
>UniRef50_Q15303 Cluster: Receptor tyrosine-protein kinase erbB-4
precursor; n=58; Euteleostomi|Rep: Receptor
tyrosine-protein kinase erbB-4 precursor - Homo sapiens
(Human)
Length = 1308
Score = 161 bits (390), Expect = 1e-37
Identities = 98/238 (41%), Positives = 138/238 (57%), Gaps = 15/238 (6%)
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN 919
LK VK LG GAFG VY+G++ + ++PVA+K L E + +A +F+ EA IMA +
Sbjct: 718 LKRVKVLGSGAFGTVYKGIWVPEG-ETVKIPVAIKILNETTGPKANVEFMDEALIMASMD 776
Query: 920 HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCK 979
H ++V L+GVC + +V +L+ G L ++ E K S L LL V + K
Sbjct: 777 HPHLVRLLGVCLSPTIQ-LVTQLMPHGCLLEYVHEH--KDNIGSQL----LLNWCVQIAK 829
Query: 980 GCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY--RADYYKKGGKAMLPI 1037
G YLE +R +HRD+AARN L+ S P V KI DFG+AR + +Y GGK +PI
Sbjct: 830 GMMYLEERRLVHRDLAARNVLVKS--PNHV-KITDFGLARLLEGDEKEYNADGGK--MPI 884
Query: 1038 KWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
KWM E FT ++DVWS+GV +WE+ + G PY G RE+ +L+ G RL +P
Sbjct: 885 KWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQP 942
>UniRef50_Q4SQX3 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14528, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 780
Score = 160 bits (389), Expect = 2e-37
Identities = 97/253 (38%), Positives = 137/253 (54%), Gaps = 16/253 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ +K+ K +G G FGEV G R R ++PVA+KTL T + + DFL EA+
Sbjct: 409 EIEASRIKIEKIIGSGEFGEVCYG--RMRLPGKRDIPVALKTLKVGYTEKQKRDFLAEAS 466
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IMA+F+H N++ L GV P I+ E + G L +FLR T+ L+
Sbjct: 467 IMAQFDHPNVIRLEGVVTHSKPVMIITEYMENGSLDSFLRR------HDGQFTIIQLVGL 520
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR---DIYRADYYKKG 1030
+ G YL +IHRD+AARN L+ S V K++DFG++R D A Y G
Sbjct: 521 LRGIAAGMTYLSDLGYIHRDLAARNILVNSN---LVCKVSDFGLSRVLEDDPDAAYTTSG 577
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
GK +PI+W PEA F++ +DVWS+GV++WEV S G PY NR+V++ V G
Sbjct: 578 GK--IPIRWTAPEAITFRKFSSSSDVWSYGVVMWEVTSYGERPYWNLTNRDVIKSVEEGY 635
Query: 1091 RLEKPYGEGSEYH 1103
RL P G + H
Sbjct: 636 RLPAPMGCPAALH 648
>UniRef50_Q9Y1X8 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 1193
Score = 160 bits (389), Expect = 2e-37
Identities = 94/261 (36%), Positives = 146/261 (55%), Gaps = 14/261 (5%)
Query: 838 GSESFLPQGI--DVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKT 895
G+E+ P + D L +L+ + LG GAFG VY+G +R D VA+K
Sbjct: 817 GNETLRPPKLPPDATRLIITPETALEQGQVLGSGAFGTVYKGHWRPEG-DPNCYEVAIKV 875
Query: 896 LPE-LSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRE 954
L E +T Q++++ L E A+MA +H N+V L VC + ++ E + G L ++L+
Sbjct: 876 LKEETATPQSQTELLREGAVMATMDHINVVRLYCVCMGKQ-MMLITEFVRLGSLLSYLKN 934
Query: 955 SRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIAD 1014
++ + L +L S + G YLE KR +HRD+AARN L+ + ++VKI D
Sbjct: 935 NQ------ATLDAYSMLNFSRQIADGMAYLEEKRMVHRDLAARNVLVHTP---QLVKITD 985
Query: 1015 FGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPY 1074
FG+ R I + + K M+P++WM PE+ +T K+DVWSFGV +WE+ + G +PY
Sbjct: 986 FGLTRIIDVGESHYKATGGMVPLRWMAPESIFLFEYTHKSDVWSFGVTIWEILTFGRLPY 1045
Query: 1075 TGCANREVMELVSGGGRLEKP 1095
G +EV +LV G +LE+P
Sbjct: 1046 KGKNGKEVSQLVKNGQQLERP 1066
>UniRef50_Q23554 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 419
Score = 160 bits (389), Expect = 2e-37
Identities = 90/244 (36%), Positives = 135/244 (55%), Gaps = 12/244 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + +KL K LG+GAFG VY+ + + K ++ST D EA
Sbjct: 132 ELRHDQIKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEAR 191
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM ++ H N+V GVC ++ P +V+EL + G L +FL+ + + ++++D L
Sbjct: 192 IMRQYQHPNVVCFFGVCVEKEPIMLVMELASQGALDSFLKNEK------NNVSLRDKLKY 245
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYR-ADYYK-KGG 1031
S D KG YL IHRD+AARN L+ VVKI DFG+++ + A YK K
Sbjct: 246 SFDASKGLEYLHQHGCIHRDVAARNFLMHKN----VVKITDFGLSKQLSDLAHKYKLKDI 301
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+A LPI+W+ PE + +T K+DV+SFG+LLWE+F G +PY G EV + V G R
Sbjct: 302 QAKLPIRWLAPEVIVTATYTFKSDVYSFGILLWEIFMDGAIPYPGMKLAEVKQKVKNGYR 361
Query: 1092 LEKP 1095
++ P
Sbjct: 362 MDAP 365
>UniRef50_A7SZN9 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 283
Score = 160 bits (389), Expect = 2e-37
Identities = 92/249 (36%), Positives = 137/249 (55%), Gaps = 12/249 (4%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
Q+ RE+++L + LG+G FG+V +G D + AVK L +T D L E
Sbjct: 1 QIPREAVELGRTLGEGEFGKVIEG--NVTEPDGTRVHCAVKKLKRTATESDWKDLLNELD 58
Query: 914 IMAKFN-HANIVHLIGVCFDRH-PRFIVLELLAGGDLKNFLRESRPKP-----ERASALT 966
IM + H NIV+LIG C D P +++E G+L ++L+++ K E +
Sbjct: 59 IMVQVGEHPNIVNLIGACSDPEGPLMVIVEFCGNGNLLHYLQKNSNKNYSNLHEYVLTIP 118
Query: 967 MKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADY 1026
++ L + DV G +LE R +HRD+AARN LL K++DFG++RDIY
Sbjct: 119 ARERLRIAADVASGMAHLEKMRCVHRDLAARNVLLDE---ALTAKVSDFGLSRDIYTNSV 175
Query: 1027 YKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
Y+K LP KWM E+ G++T+ +D WSFGVLLWE+ + G +PY +E++ +
Sbjct: 176 YEKTTGGKLPAKWMAIESIEAGLYTSHSDAWSFGVLLWEIETGGCIPYPTFTVQEMLNSL 235
Query: 1087 SGGGRLEKP 1095
G RLEKP
Sbjct: 236 KKGYRLEKP 244
>UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
KLG - Strongylocentrotus purpuratus
Length = 1013
Score = 160 bits (388), Expect = 2e-37
Identities = 89/246 (36%), Positives = 131/246 (53%), Gaps = 9/246 (3%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
Q + ++ + +G GA+GEV V VK L E + DF E
Sbjct: 732 QFPKHDMQTITTIGHGAYGEVTLSRAAGIKDGEEATTVMVKAL-ETKEESLQLDFRREIE 790
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA---LTMKDL 970
++ K NH NIV L+GVC D P+ ++ E L GDLK FL+ +R + + LT+
Sbjct: 791 MLGKLNHENIVKLLGVCRDTEPQLMITEYLDWGDLKQFLQATRGENGTKNVPPPLTLSQK 850
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
+ V G L RFIH D+AARNCLL+ P VKI +++D+YR +Y++
Sbjct: 851 IDIVNQVALGMETLSANRFIHGDLAARNCLLS---PSMEVKICTMSVSQDLYRPEYHEYH 907
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVME-LVSGG 1089
K ++P++WMP EA + + K+DVW++G+ +WEVFS G +PYT N VM ++ G
Sbjct: 908 QK-LIPVRWMPAEAIFEDELSAKSDVWAYGIFVWEVFSQGTLPYTQLDNDAVMRAMIDGE 966
Query: 1090 GRLEKP 1095
LE P
Sbjct: 967 LMLETP 972
>UniRef50_Q6DTW4 Cluster: Tyrosine kinase receptor ron; n=6;
Eumetazoa|Rep: Tyrosine kinase receptor ron - Canis
familiaris (Dog)
Length = 998
Score = 160 bits (388), Expect = 2e-37
Identities = 95/249 (38%), Positives = 139/249 (55%), Gaps = 17/249 (6%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G Y D + AVK+L ++ Q FL E +M +H N+
Sbjct: 684 RVIGKGHFGVVYHGEYIDE--DQNRIHCAVKSLSRITEVQEAEAFLREGLLMRGLHHPNV 741
Query: 924 VHLIGVCFDRH--PRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGC 981
+ LIG+ PR ++L + GDL F+R + P T+KDL+ + V +G
Sbjct: 742 LALIGIVLPPEGLPR-VLLPYMRHGDLLRFIRSPQRNP------TVKDLISFGLQVARGM 794
Query: 982 RYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY--KKGGKAMLPIKW 1039
YL ++F+HRD+AARNC+L VK+ADFG+ARDI +YY ++ A LP+KW
Sbjct: 795 EYLAEQKFVHRDLAARNCMLDE---SFTVKVADFGLARDILDKEYYSVRQHRHARLPVKW 851
Query: 1040 MPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP-YGE 1098
M E+ FTTK+DVWSFGVLLWE+ + G PY ++++ ++ G RL +P Y
Sbjct: 852 MALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLIQFLAQGRRLPQPEYCP 911
Query: 1099 GSEYHKFKR 1107
S Y +R
Sbjct: 912 NSLYMVMQR 920
>UniRef50_Q9N3S5 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 618
Score = 160 bits (388), Expect = 2e-37
Identities = 98/253 (38%), Positives = 141/253 (55%), Gaps = 20/253 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTL-PELSTGQAESDFLMEAA 913
V+R ++ VK +G+G FGEVY L + + D VAVK+L P+ S A + FL EA
Sbjct: 323 VNRSEVRRVKEIGRGQFGEVY--LAKWKGVD-----VAVKSLKPDHSEQLANTQFLEEAK 375
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESR----PKPERASALTMKD 969
+ K +H N++HL+ VC P I+ E + G L +L++ P P + K+
Sbjct: 376 TLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWLQKLTKTLPPIPLMSEETGRKN 435
Query: 970 LLL---CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRV--VKIADFGMAR--DIY 1022
+L+ S V G YL + +HRD+AARN L+ + V VK+ADFG+AR D+
Sbjct: 436 VLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVG 495
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
+Y K MLP KWM PE + + +F TKTDVWS+G+LLWE+ +LG PY G
Sbjct: 496 DENYVMKTDN-MLPWKWMAPECFDEQIFNTKTDVWSYGILLWEIGTLGKTPYRGWDYEGT 554
Query: 1083 MELVSGGGRLEKP 1095
+E +S G L +P
Sbjct: 555 LEHLSRGYVLPRP 567
>UniRef50_Q86LZ8 Cluster: Insulin receptor protein kinase; n=2;
Schistosoma|Rep: Insulin receptor protein kinase -
Schistosoma mansoni (Blood fluke)
Length = 1499
Score = 160 bits (388), Expect = 2e-37
Identities = 86/211 (40%), Positives = 121/211 (57%), Gaps = 8/211 (3%)
Query: 889 MPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDR---HPRFIVLELLAG 945
+ VAVKTL ST +F EA+ M + N IV +G+ + HP I++E +A
Sbjct: 1248 LEVAVKTLFPASTMDDIREFYNEASFMKQLNCMYIVQFLGIALRQPSSHP-VIIMEYMAF 1306
Query: 946 GDLKNFLRESRPKPERASALTMKDLLL-CSVDVCKGCRYLETKRFIHRDIAARNCLLTSR 1004
GDL +LR+ K + L + ++ + G YL IHRD+AARNCL+ S
Sbjct: 1307 GDLATYLRQQMSKDDCPQGSIDTQLAINWAIQLATGMNYLAELHIIHRDLAARNCLVNSM 1366
Query: 1005 GPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLW 1064
VKIADFG+AR + +YY+K G+A LP++WM PE FTTK+DVWS+GV+LW
Sbjct: 1367 ---LTVKIADFGLARLVNNQEYYRKIGQARLPVRWMAPETLSSAYFTTKSDVWSYGVVLW 1423
Query: 1065 EVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ + +PY G ++ EVM+ V GG L P
Sbjct: 1424 EIATFASLPYPGLSHEEVMKFVCDGGHLNLP 1454
>UniRef50_Q674V1 Cluster: Vascular endothelial growth factor receptor;
n=1; Podocoryne carnea|Rep: Vascular endothelial growth
factor receptor - Podocoryne carnea
Length = 1254
Score = 160 bits (388), Expect = 2e-37
Identities = 82/215 (38%), Positives = 126/215 (58%), Gaps = 13/215 (6%)
Query: 891 VAVKTLPELSTGQAESDFLMEAAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLK 949
VAVKTL + + D E I+ H NIV+L+G C +++LE G+L
Sbjct: 895 VAVKTLKDDAAEGEYKDLASELKILIHLGEHKNIVNLLGACTTNGKLYVILECCPRGNLL 954
Query: 950 NFLRESRP--KP-------ERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCL 1000
FLR R +P + + T DLL+ + V K +L++++ +HRD+AARN L
Sbjct: 955 TFLRGKRETFQPVWTKYDTDMENEFTYIDLLMIVIQVAKRMDFLQSQKCVHRDLAARNVL 1014
Query: 1001 LTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFG 1060
+ GP ++KIADFG+ARDIY+ ++Y K +LP+KWM PE+ D V+T+ +D+WS+G
Sbjct: 1015 V---GPDYIMKIADFGLARDIYKDEFYLKETTGLLPVKWMAPESLFDKVYTSMSDIWSYG 1071
Query: 1061 VLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
++LWE F+LG PY G ++ + G R+E+P
Sbjct: 1072 IVLWEAFTLGGSPYPGLPTEDLFGFLEDGKRMERP 1106
>UniRef50_Q5K4G5 Cluster: Receptor tyrosine kinase; n=1; Suberites
domuncula|Rep: Receptor tyrosine kinase - Suberites
domuncula (Sponge)
Length = 715
Score = 160 bits (388), Expect = 2e-37
Identities = 92/239 (38%), Positives = 135/239 (56%), Gaps = 9/239 (3%)
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN 919
L L LG GAFG V + + + VAVK L E ++ + E D +ME ++
Sbjct: 387 LNLKDDLGSGAFGVVKKAELFDPISQTTSI-VAVKMLKESASTEDEKDIIMELKVLYHVG 445
Query: 920 -HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVC 978
H N+V +G + +++E G+L FLR R + S L++++ + + V
Sbjct: 446 EHCNVVSFLGASVHKGKLHLIVEYCERGNLLQFLRSKRG--DMKSPLSVQNQVAIASQVA 503
Query: 979 KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIK 1038
G YL +KR IHRD+AARN L+T +K+ADFG+AR +Y + Y+ GK LPIK
Sbjct: 504 NGMAYLASKRCIHRDLAARNVLITK---DLTLKVADFGLARKMY-SSVYRPSGKR-LPIK 558
Query: 1039 WMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKPYG 1097
WM PE +DGV T+K+DVWSFG+LLWE+ +LG PY G + V+ + G R+ +P G
Sbjct: 559 WMAPEGILDGVCTSKSDVWSFGILLWEIMTLGRTPYPGRSAHWVIRDIENGYRMPQPDG 617
>UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle specific
tyrosine kinase receptor; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to muscle specific
tyrosine kinase receptor - Strongylocentrotus purpuratus
Length = 827
Score = 159 bits (387), Expect = 3e-37
Identities = 94/258 (36%), Positives = 134/258 (51%), Gaps = 10/258 (3%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+ +R ++ K +G+GAFG V+ A AE VAVK L + F EA
Sbjct: 533 EYNRNNVIYEKDIGEGAFGRVFMASAPKLVAGEAETSVAVKMLKATADKVVTEYFNREAQ 592
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRE-------SRPKPERASALT 966
++A+F+H NIV L+GVCF P ++LE ++ GDL+++L SR S L
Sbjct: 593 MIARFSHQNIVKLLGVCFVGRPLCLLLEYMSEGDLEDYLHSRSPHRSNSRTSNSPGSGLK 652
Query: 967 MKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADY 1026
+ L + + G YL F+HRDIA RNCL+ SR VKI+DFG+AR + +
Sbjct: 653 TYEKLNMAKQIACGMAYLNEMMFVHRDIATRNCLINSRTD---VKISDFGLARYVGHKEC 709
Query: 1027 YKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
+ + +PI+W PEA D FT +DVWSFGVLLWE+FS PY ++ +V
Sbjct: 710 FVGHKEEHIPIRWTAPEALWDYQFTYASDVWSFGVLLWELFSYAEQPYLNLSHEDVFLHT 769
Query: 1087 SGGGRLEKPYGEGSEYHK 1104
G RL + H+
Sbjct: 770 RQGYRLSSLENTPQKVHQ 787
>UniRef50_Q6PFV6 Cluster: Ephrin receptor; n=11; Tetrapoda|Rep: Ephrin
receptor - Mus musculus (Mouse)
Length = 819
Score = 159 bits (386), Expect = 4e-37
Identities = 92/245 (37%), Positives = 136/245 (55%), Gaps = 16/245 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + + + +G G FGEV G R + E+PVA+KTL T + DFL EA+
Sbjct: 485 EIEASCITIERVIGAGEFGEVCSG--RLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEAS 542
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +F+H NI+HL GV P IV E + G L FL+++ + T+ L+
Sbjct: 543 IMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQ------FTVIQLVGM 596
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR---DIYRADYYKKG 1030
+ G +YL ++HRD+AARN L+ S V K++DFG++R D A Y +G
Sbjct: 597 LRGIAAGMKYLSDMGYVHRDLAARNILINSN---LVCKVSDFGLSRVLEDDPEAAYTTRG 653
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
GK +PI+W PEA FT+ +DVWS+G+++WEV S G PY N++V++ V G
Sbjct: 654 GK--IPIRWTAPEAIAFRKFTSSSDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGY 711
Query: 1091 RLEKP 1095
RL P
Sbjct: 712 RLPSP 716
>UniRef50_A7SL46 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 252
Score = 159 bits (386), Expect = 4e-37
Identities = 81/196 (41%), Positives = 117/196 (59%), Gaps = 10/196 (5%)
Query: 907 DFLMEAAIMAKF-NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP------ 959
+FL E ++M K +H NIV+ + + P +V+E L GDL ++LR +R K
Sbjct: 13 EFLKEISLMKKLGSHKNIVNFLCCSTVKEPFMLVVEFLPKGDLLDYLRRNRSKQNDETGE 72
Query: 960 ERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
+ +T +DLL S + G YL K F+HRD+AARN L+ + VK+ADFG+ R
Sbjct: 73 QEDEMITPQDLLSFSYQIAAGMEYLSKKGFVHRDLAARNVLVADN---KQVKVADFGLTR 129
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y Y+ LPIKWM PEA D +FTT++DVWS+GV+LWE+ +LG PY +
Sbjct: 130 DLYEESAYQGHSNRKLPIKWMSPEAIYDQIFTTESDVWSYGVVLWEIATLGGAPYPTIST 189
Query: 1080 REVMELVSGGGRLEKP 1095
R+V ++ G R+EKP
Sbjct: 190 RDVFVMLRSGYRMEKP 205
>UniRef50_A7S934 Cluster: Predicted protein; n=4; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 304
Score = 159 bits (385), Expect = 5e-37
Identities = 94/265 (35%), Positives = 143/265 (53%), Gaps = 26/265 (9%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEM----PVAVKTLPELSTGQAESDFL 909
++ R+ L + + LG GAFG V + + ++ P AVK L E T D
Sbjct: 1 EIPRDDLTIERQLGSGAFGVVKKAKTEEPEEEKGKVLEIVPCAVKMLKENPTESELRDLC 60
Query: 910 MEAAIMAKF-NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE-------- 960
E AIMA +H NIV L+G C P ++V++L G ++++E R E
Sbjct: 61 NEIAIMALVGDHPNIVSLLGACTVNGPLWLVVKLAENGCFLDYIKEHRSVVEYENTENKI 120
Query: 961 ----------RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVV 1010
+ + +T K+ + ++ KG R+LE K+ +HRD+AARN LL V
Sbjct: 121 HSYENVTEKTQGAPMTEKEKFKFAYEIAKGMRHLEKKKCVHRDLAARNILLNV---DNVA 177
Query: 1011 KIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLG 1070
++DFG++RD+Y + Y +LP++WM E+ D +TTK+DVWS+GVLLWE+ S G
Sbjct: 178 MVSDFGLSRDVYESGAYDNTTGGVLPVRWMAIESLEDYTYTTKSDVWSYGVLLWEMESGG 237
Query: 1071 VMPYTGCANREVMELVSGGGRLEKP 1095
+MPY G + E++E + G RLEKP
Sbjct: 238 LMPYAGMSGVEILERLKQGYRLEKP 262
>UniRef50_Q15516 Cluster: Tyrosine kinase; n=1; Homo sapiens|Rep:
Tyrosine kinase - Homo sapiens (Human)
Length = 600
Score = 159 bits (385), Expect = 5e-37
Identities = 90/245 (36%), Positives = 141/245 (57%), Gaps = 12/245 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R L L K LG+G G VY+GL+ ++PVA+KTL +L T A + L EA++
Sbjct: 237 IDRNLLILGKILGEGEKGTVYEGLWNIPEGKEVKIPVAIKTL-KLDT-MANKEILDEASV 294
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLE--LLAGGDLKNFLRESRPKPERASALTMKDLLL 972
M F + ++V L+G+C +++ E LL K+ + R + ++ LL
Sbjct: 295 MKGFGNPHVVRLLGICMTS-TIYVITEYCLLVYRRNKDKAEQHRSNCAELNP-PLQTLLK 352
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK 1032
VD+ G YL + F+HRD+AARNC+L V +ADFG+++ IY DYY++G
Sbjct: 353 FMVDIALGMEYLSNRNFLHRDLAARNCMLRD---DMTVCVADFGLSKKIYSGDYYRQGRI 409
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL--GVMPYTGCANREVMELVSGGG 1090
A +P+KW+ E+ D V+ TK+DVW+FGV +WE+ + G+ PY G N E+ + + G
Sbjct: 410 AKMPVKWIAIESLADRVY-TKSDVWAFGVTMWEIATTLRGMTPYPGVQNHEMYDYLLHGH 468
Query: 1091 RLEKP 1095
RL++P
Sbjct: 469 RLKQP 473
>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
sapiens (Human)
Length = 505
Score = 159 bits (385), Expect = 5e-37
Identities = 101/242 (41%), Positives = 138/242 (57%), Gaps = 19/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R+SL+LV+ LG G FGEV+ G Y++ M VA+KTL E T E+ FL EA
Sbjct: 235 EIPRQSLRLVRKLGSGQFGEVWMGYYKNN------MKVAIKTLKE-GTMSPEA-FLGEAN 286
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M H +V L V + P +IV E +A G L +FL K + S L++ L+
Sbjct: 287 VMKALQHERLVRLYAVV-TKEPIYIVTEYMARGCLLDFL-----KTDEGSRLSLPRLIDM 340
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
S + +G Y+E IHRD+ A N L++ KIADFG+AR I ++Y + G A
Sbjct: 341 SAQIAEGMAYIERMNSIHRDLRAANILVSE---ALCCKIADFGLAR-IIDSEYTAQEG-A 395
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PEA GVFT K DVWSFGVLL EV + G +PY G +N EV+ + G R+
Sbjct: 396 KFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMP 455
Query: 1094 KP 1095
+P
Sbjct: 456 RP 457
>UniRef50_UPI00015B4B9F Cluster: PREDICTED: similar to prenylcysteine
oxidase 1; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to prenylcysteine oxidase 1 - Nasonia vitripennis
Length = 807
Score = 158 bits (384), Expect = 7e-37
Identities = 88/255 (34%), Positives = 138/255 (54%), Gaps = 15/255 (5%)
Query: 841 SFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY----QGLYRHRSADA-AEMPVAVKT 895
S L + ++ +P R L+++ L +GAFG VY +G+ + + + VAVK
Sbjct: 27 SALKKRLEQTSVPLFPRHRLRMLSKLAEGAFGSVYIAEAEGIPEYGTTTTLGKRLVAVKF 86
Query: 896 LPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLR-- 953
L + + + DF + I+A NI ++G C P +V+E L GDL FL+
Sbjct: 87 LLPEANEKEKLDFQRDVRILAALEDRNIARVLGACCREEPFCVVMEYLEHGDLCQFLKTH 146
Query: 954 ----ESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRV 1009
++ P L+ L+ + + G RYLE F+HRD+A RNCL+ G
Sbjct: 147 VTAEDAHSMPIGVKTLSFNCLIYMAAQIASGMRYLENLNFVHRDLATRNCLV---GKAYH 203
Query: 1010 VKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSL 1069
+KI+DFG ++Y DYYK G LP++WM E+ + G +TTK+DVWSF V+LWE+ +L
Sbjct: 204 IKISDFGTDNELYACDYYKVDGGIPLPVRWMAWESLVLGKYTTKSDVWSFAVMLWEILNL 263
Query: 1070 G-VMPYTGCANREVM 1083
G +PY +++EV+
Sbjct: 264 GRRVPYEHLSDQEVV 278
>UniRef50_UPI0000E47549 Cluster: PREDICTED: similar to Cek8; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Cek8 - Strongylocentrotus purpuratus
Length = 775
Score = 158 bits (384), Expect = 7e-37
Identities = 92/243 (37%), Positives = 134/243 (55%), Gaps = 14/243 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ +++++ +G G FG+V GL D + VAVKTL +T + SDFL EA+
Sbjct: 411 EIDATQIRILEVIGGGEFGDVCSGLML--MPDKTTIKVAVKTLKTGATDKDRSDFLSEAS 468
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +F+H N++ L+GV P IV E + G L +LRE+ + T+ LL
Sbjct: 469 IMGQFDHPNVIKLLGVVTKTRPAMIVTEFMENGSLDKYLRENDGR------FTVTQLLGM 522
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMA-RDIYRADYYKKGGK 1032
V G R+L F+HRD+AARN L+ V K+ADFG++ R Y +GGK
Sbjct: 523 MRGVGFGMRFLSEMNFVHRDLAARNILVNEH---LVCKVADFGLSRRKELDGAYETRGGK 579
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
+PI+W PEA FT+ +DVWS GV++WE+ S G PY N++V++ V G RL
Sbjct: 580 --IPIRWTAPEAIGYKKFTSASDVWSLGVVMWEIMSYGERPYWNWPNQDVIKAVEKGYRL 637
Query: 1093 EKP 1095
P
Sbjct: 638 PPP 640
>UniRef50_Q9V4E5 Cluster: CG1511-PC, isoform C; n=12; Diptera|Rep:
CG1511-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1096
Score = 158 bits (384), Expect = 7e-37
Identities = 87/244 (35%), Positives = 137/244 (56%), Gaps = 13/244 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + + +G G FG+V +G + ++ VA+KTL S+ +A DFL EA+
Sbjct: 735 EIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEAS 794
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +F+H N+++L GV +P I+ E + G L FLR + K + + M
Sbjct: 795 IMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLR---- 850
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD--YYKKGG 1031
+ G YL ++HRD+AARN L+ ++ + KIADFG++R+I A Y +GG
Sbjct: 851 --GIASGMSYLSDMNYVHRDLAARNVLVNAQ---LICKIADFGLSREIENASDAYTTRGG 905
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
K +P++W PEA FT+ +DVWS+GV+LWEV S G PY +N++V++ + G R
Sbjct: 906 K--IPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYR 963
Query: 1092 LEKP 1095
L P
Sbjct: 964 LPAP 967
>UniRef50_Q61G93 Cluster: Putative uncharacterized protein CBG11320;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG11320 - Caenorhabditis
briggsae
Length = 2330
Score = 158 bits (384), Expect = 7e-37
Identities = 90/241 (37%), Positives = 140/241 (58%), Gaps = 7/241 (2%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSAD-AAEMPVAVKTLPELSTGQA--ESDF 908
LP V +++V+ + ++G V++G+ ++ VAVK L S F
Sbjct: 1834 LPIVDYNDVEIVRHISDCSYGSVHEGIAEEVPLSWEKQVKVAVKQLRPKSANHDFDRMMF 1893
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA ++ +H NIV +GVC I+LE + GG+L NFLRES P +AS L+ +
Sbjct: 1894 MKEAILLNNLDH-NIVKELGVCVSPGQGLILLEYMEGGNLLNFLRESAPSEMQASELSTR 1952
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
DLL SVD+ +G YLE +H++++AR CLL+ R PG V K+ + GM R + + + +
Sbjct: 1953 DLLAISVDIARGMNYLERLPHVHKNLSARKCLLSGR-PG-VAKL-EMGMPRALSKGEINR 2009
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
++M +KWM PE + D +FT+K+DVW++GVLL+E+FS G PY +R V+ V
Sbjct: 2010 VDLESMQSVKWMAPEVFKDLMFTSKSDVWAYGVLLYEIFSFGEEPYGSMDSRRVITDVRD 2069
Query: 1089 G 1089
G
Sbjct: 2070 G 2070
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase Yes;
n=422; root|Rep: Proto-oncogene tyrosine-protein kinase
Yes - Homo sapiens (Human)
Length = 543
Score = 158 bits (384), Expect = 7e-37
Identities = 102/251 (40%), Positives = 137/251 (54%), Gaps = 18/251 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ RESL+L LGQG FGEV+ G + + VA+KTL T E+ FL EA
Sbjct: 271 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTK------VAIKTLKP-GTMMPEA-FLQEAQ 322
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM K H +V L V + P +IV E ++ G L +FL+E K L + L+
Sbjct: 323 IMKKLRHDKLVPLYAVVSEE-PIYIVTEFMSKGSLLDFLKEGDGK-----YLKLPQLVDM 376
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + G Y+E +IHRD+ A N L+ G V KIADFG+AR I +Y + G A
Sbjct: 377 AAQIADGMAYIERMNYIHRDLRAANILV---GENLVCKIADFGLARLIEDNEYTARQG-A 432
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PEA + G FT K+DVWSFG+L E+ + G +PY G NREV+E V G R+
Sbjct: 433 KFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMP 492
Query: 1094 KPYGEGSEYHK 1104
P G H+
Sbjct: 493 CPQGCPESLHE 503
>UniRef50_P54756 Cluster: Ephrin type-A receptor 5 precursor; n=103;
Euteleostomi|Rep: Ephrin type-A receptor 5 precursor -
Homo sapiens (Human)
Length = 1037
Score = 158 bits (384), Expect = 7e-37
Identities = 92/245 (37%), Positives = 136/245 (55%), Gaps = 16/245 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + + + +G G FGEV G R + E+PVA+KTL T + DFL EA+
Sbjct: 669 EIEASCITIERVIGAGEFGEVCSG--RLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEAS 726
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +F+H NI+HL GV P IV E + G L FL+++ + T+ L+
Sbjct: 727 IMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQ------FTVIQLVGM 780
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR---DIYRADYYKKG 1030
+ G +YL ++HRD+AARN L+ S V K++DFG++R D A Y +G
Sbjct: 781 LRGISAGMKYLSDMGYVHRDLAARNILINSN---LVCKVSDFGLSRVLEDDPEAAYTTRG 837
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
GK +PI+W PEA FT+ +DVWS+G+++WEV S G PY N++V++ V G
Sbjct: 838 GK--IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGY 895
Query: 1091 RLEKP 1095
RL P
Sbjct: 896 RLPSP 900
>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
protein-tyrosine kinase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
kinase - Strongylocentrotus purpuratus
Length = 837
Score = 158 bits (383), Expect = 9e-37
Identities = 94/235 (40%), Positives = 130/235 (55%), Gaps = 20/235 (8%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTL--PELSTGQAESDFLMEAAIMAKFNHANI 923
+GQG FG V +G Y+ + + VA+KTL L TGQ E FL EA +M +H I
Sbjct: 569 IGQGEFGSVLEGKYKEKDR---WVKVALKTLHADHLQTGQKE--FLREAKVMCGLDHPCI 623
Query: 924 VHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRY 983
V L+GVC P +V EL++ G L +FL+ ++T DL L + + G Y
Sbjct: 624 VKLMGVCLGP-PMMLVQELVSQGALLDFLQND--------SITASDLKLWATQIASGMMY 674
Query: 984 LETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI-YRADYYKKGGKAMLPIKWMPP 1042
LE K+F+HRD+AARN LL ++G KI+DFG++R DYY+ P+KW P
Sbjct: 675 LEGKKFVHRDLAARNILLENKGQA---KISDFGLSRATGANNDYYRSTTGGRWPVKWYAP 731
Query: 1043 EAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKPYG 1097
E+ G F+ +DVW FGV LWE+ S G PY EV++ + G RL +P G
Sbjct: 732 ESIYYGTFSHSSDVWGFGVTLWEMNSRGAQPYGEKTGAEVIKQIENGHRLNRPEG 786
>UniRef50_Q68KJ7 Cluster: HER2; n=3; Amniota|Rep: HER2 - Felis
silvestris catus (Cat)
Length = 304
Score = 158 bits (383), Expect = 9e-37
Identities = 96/238 (40%), Positives = 139/238 (58%), Gaps = 15/238 (6%)
Query: 860 LKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFN 919
L+ VK LG GAFG VY+G++ + ++PVA+K L E ++ +A + L EA +MA
Sbjct: 73 LRKVKVLGSGAFGTVYKGIWIP-DGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVG 131
Query: 920 HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCK 979
+ L+G+C + +V +L+ G L + +RE R + L +DLL V + K
Sbjct: 132 SPYVSRLLGICLTSTVQ-LVTQLMPYGCLLDHVREHRGR------LGSQDLLNWCVQIAK 184
Query: 980 GCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGGKAMLPI 1037
G YLE R +HRD+AARN L+ S P V KI DFG+AR DI +Y+ GGK +PI
Sbjct: 185 GMSYLEDVRLVHRDLAARNVLVKS--PNHV-KITDFGLARLLDIDETEYHADGGK--VPI 239
Query: 1038 KWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
KWM E+ + FT ++DVWS+GV + E+ + G PY G RE+ +LV G RL +P
Sbjct: 240 KWMALESILRRRFTHQSDVWSYGVTVRELMTFGAKPYDGIPAREIPDLVEKGERLPQP 297
>UniRef50_Q08345 Cluster: Epithelial discoidin domain-containing
receptor 1 precursor; n=40; Mammalia|Rep: Epithelial
discoidin domain-containing receptor 1 precursor - Homo
sapiens (Human)
Length = 913
Score = 158 bits (383), Expect = 9e-37
Identities = 100/268 (37%), Positives = 141/268 (52%), Gaps = 29/268 (10%)
Query: 843 LPQGIDVRGLPQVS--RESLKLVKALGQGAFGEVY-------QGL----YRHRSADAAEM 889
LP G G P+V R L+ + LG+G FGEV+ Q L + +
Sbjct: 591 LPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPL 650
Query: 890 PVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLK 949
VAVK L +T A +DFL E IM++ NI+ L+GVC P ++ + + GDL
Sbjct: 651 LVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLN 710
Query: 950 NFLR---------ESRPKPERAS---ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAAR 997
FL E P +A+ ++ LL + + G RYL T F+HRD+A R
Sbjct: 711 QFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATR 770
Query: 998 NCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVW 1057
NCL+ G +KIADFGM+R++Y DYY+ G+A+LPI+WM E + G FTT +DVW
Sbjct: 771 NCLV---GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVW 827
Query: 1058 SFGVLLWEVFSL-GVMPYTGCANREVME 1084
+FGV LWEV L P+ + +V+E
Sbjct: 828 AFGVTLWEVLMLCRAQPFGQLTDEQVIE 855
>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome shotgun
sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 921
Score = 157 bits (382), Expect = 1e-36
Identities = 81/184 (44%), Positives = 113/184 (61%), Gaps = 10/184 (5%)
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAG-GDLKNFLRESRPKPERASALTMKDLLL 972
I+ +++H N+V LIGVC + P +IV+EL+ G GD FLR + L K L+
Sbjct: 710 ILKQYDHPNVVKLIGVCTQKQPIYIVMELIQGSGDFLTFLRN------QGRDLKPKALVK 763
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK 1032
+ +V G YLE+K+ IHRD+AARNCL+ VKI+DFGM+R Y +GG
Sbjct: 764 MAENVASGMAYLESKKCIHRDLAARNCLVAENNS---VKISDFGMSRQDDDGVYLAEGGL 820
Query: 1033 AMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRL 1092
+PIKW PEA G +TT++DVWSFG+LLWE FSLG+ PY +N++ + V G R+
Sbjct: 821 RQIPIKWTAPEALNYGRYTTQSDVWSFGILLWETFSLGLTPYMSMSNQQTRDEVEKGYRM 880
Query: 1093 EKPY 1096
P+
Sbjct: 881 PAPH 884
>UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma
mansoni|Rep: Tyrosine kinase 5 - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 157 bits (382), Expect = 1e-36
Identities = 96/245 (39%), Positives = 137/245 (55%), Gaps = 22/245 (8%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++S+ S+ L++ LG G FGEV++G + + VAVKTL + + + DFL EA
Sbjct: 298 EISKSSIVLIEKLGAGQFGEVWKGTWNGTTE------VAVKTLKQGT--MTKEDFLKEAR 349
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM H +V L VC + P +IV EL+ G L +LR+ K L + L+
Sbjct: 350 IMRAAQHPKLVRLYAVCTE-DPIYIVTELMCNGSLLQYLRDGPGKN-----LLINQLVDM 403
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR---DIYRADYYKKG 1030
+ G YLE + +IHRD+AARN L+ G VK+ADFG+AR D Y +K
Sbjct: 404 MAQIANGMAYLEKEHYIHRDLAARNILV---GENNCVKVADFGLARMVEDHYCTYMAQKS 460
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
K PIKW PEA + G FT K+DVWSFG++++E+ +LG +PY N E + VS G
Sbjct: 461 TK--FPIKWTAPEAALMGRFTIKSDVWSFGIVIYELITLGQVPYPSMNNTETLHQVSTGY 518
Query: 1091 RLEKP 1095
R+ +P
Sbjct: 519 RMPRP 523
>UniRef50_Q8I7I5 Cluster: Roller: helically twisted, animals roll when
moving protein 3, isoform a; n=5; Bilateria|Rep: Roller:
helically twisted, animals roll when moving protein 3,
isoform a - Caenorhabditis elegans
Length = 2456
Score = 157 bits (381), Expect = 2e-36
Identities = 101/307 (32%), Positives = 160/307 (52%), Gaps = 11/307 (3%)
Query: 797 KKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSE-----SFLPQGID--V 849
K R +Q +KR E E RL N ++ + P Y SE S+ ++ +
Sbjct: 1871 KSRRRQQQKKREAEDERNCIRLDVVANMNFSSSHQSLPPEYESEMRSSLSYTVLFLNNLI 1930
Query: 850 RGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSAD-AAEMPVAVKTLPELSTGQAESDF 908
LP V+ ++ + A+G V+ G ++ VA+K L + Q + F
Sbjct: 1931 SDLPVVNYSTVTFNDYIDTCAYGIVHSGTAEEVPMSWEKDVRVAIKKLKPNHSFQEKMMF 1990
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA ++ +H NIV +GVC I+LE + GG+L FL++S P ++S L+ +
Sbjct: 1991 MKEAILLNNLDHPNIVKELGVCITPGQELILLEYMEGGNLLKFLQKSTPNEYQSSELSPR 2050
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
DLL SVD+ +G YLE +H++++AR CLL R PG V K+ + GM++++ +
Sbjct: 2051 DLLSISVDIARGMNYLERLPHVHKNLSARKCLLAGR-PG-VTKL-EMGMSKELSNGQVNR 2107
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+ M ++WM PE D F++K+DVW++GVLL+EVFS G +PY NR +M V
Sbjct: 2108 SDLENMEIVRWMAPEVLKDFQFSSKSDVWAYGVLLYEVFSFGEVPYGDKDNRRIMTDVRN 2167
Query: 1089 GGRLEKP 1095
G L P
Sbjct: 2168 GSVLPIP 2174
>UniRef50_Q04912 Cluster: Macrophage-stimulating protein receptor
precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CD136
antigen) (CDw136) [Contains: Macrophage- stimulating
protein receptor alpha chain; Macrophage-stimulating
protein receptor beta chain]; n=15; Eutheria|Rep:
Macrophage-stimulating protein receptor precursor (EC
2.7.10.1) (MSP receptor) (p185-Ron) (CD136 antigen)
(CDw136) [Contains: Macrophage- stimulating protein
receptor alpha chain; Macrophage-stimulating protein
receptor beta chain] - Homo sapiens (Human)
Length = 1400
Score = 157 bits (381), Expect = 2e-36
Identities = 88/235 (37%), Positives = 132/235 (56%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G Y ++ + + A+K+L ++ Q FL E +M NH N+
Sbjct: 1086 RVIGKGHFGVVYHGEYIDQAQNRIQC--AIKSLSRITEMQQVEAFLREGLLMRGLNHPNV 1143
Query: 924 VHLIGVCFDRHPR-FIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ LIG+ ++L + GDL F+R + P T+KDL+ + V +G
Sbjct: 1144 LALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNP------TVKDLISFGLQVARGME 1197
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY--KKGGKAMLPIKWM 1040
YL ++F+HRD+AARNC+L VK+ADFG+ARDI +YY ++ A LP+KWM
Sbjct: 1198 YLAEQKFVHRDLAARNCMLDE---SFTVKVADFGLARDILDREYYSVQQHRHARLPVKWM 1254
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGVLLWE+ + G PY ++ ++ G RL +P
Sbjct: 1255 ALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQP 1309
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 157 bits (381), Expect = 2e-36
Identities = 96/244 (39%), Positives = 145/244 (59%), Gaps = 24/244 (9%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ + LKL++ +G+G FG+V G YR VAVK + +T QA FL EA++
Sbjct: 190 LNMKELKLLQTIGKGEFGDVMLGDYRGNK-------VAVKCIKNDATAQA---FLAEASV 239
Query: 915 MAKFNHANIVHLIGVCFD-RHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
M + H+N+V L+GV + + +IV E +A G L ++LR SR + S L LL
Sbjct: 240 MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLR-SRGR----SVLGGDCLLKF 294
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
S+DVC+ YLE F+HRD+AARN L++ V K++DFG+ ++ A + GK
Sbjct: 295 SLDVCEAMEYLEGNNFVHRDLAARNVLVSE---DNVAKVSDFGLTKE---ASSTQDTGK- 347
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LP+KW PEA + F+TK+DVWSFG+LLWE++S G +PY ++V+ V G +++
Sbjct: 348 -LPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMD 406
Query: 1094 KPYG 1097
P G
Sbjct: 407 APDG 410
>UniRef50_Q7Z1L9 Cluster: Neurite outgrowth regulated kinase; n=1;
Aplysia californica|Rep: Neurite outgrowth regulated
kinase - Aplysia californica (California sea hare)
Length = 991
Score = 157 bits (380), Expect = 2e-36
Identities = 94/277 (33%), Positives = 147/277 (53%), Gaps = 33/277 (11%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ SLK LGQGAFG+V G Y + VA+K + E + + D + E
Sbjct: 580 ELDPHSLKFSTLLGQGAFGKVVTGYYE-------DQKVAIKIVREGAPLSYKEDLVAEIN 632
Query: 914 IMAKF-NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPE------------ 960
+M + +H NIV LIG C P +V+E + G+L+NFL++ R +
Sbjct: 633 LMKRIGSHPNIVCLIGACTMSEPIALVMEYVPYGNLQNFLKKCRMDGDVRKRCDGPSEIT 692
Query: 961 ----------RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVV 1010
+ +T D+L + V YL K+++HRD+AARN L+ +VV
Sbjct: 693 YTVIQDNGSMESGVVTPVDMLSFARQVAMAMEYLAEKKYVHRDLAARNVLIDYN---KVV 749
Query: 1011 KIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLG 1070
K+ DFG++RDI+ ++YKK LP+KWM E+ D +FTT++DVWSFG+LLWE+ ++G
Sbjct: 750 KVCDFGLSRDIFNDNHYKKLTNGKLPLKWMAIESLRDRMFTTQSDVWSFGILLWEIVTMG 809
Query: 1071 VMPYTGCANREVMELVSGGGRLEKPYGEGSEYHKFKR 1107
PY A ++ ++S G R+++P E + R
Sbjct: 810 ASPYPNVALADLYYVLSNGYRMDRPSNCSQELYAIMR 846
>UniRef50_P04412 Cluster: Epidermal growth factor receptor precursor;
n=129; Endopterygota|Rep: Epidermal growth factor
receptor precursor - Drosophila melanogaster (Fruit fly)
Length = 1426
Score = 157 bits (380), Expect = 2e-36
Identities = 95/270 (35%), Positives = 151/270 (55%), Gaps = 15/270 (5%)
Query: 829 LAMAFNPHYGSESFLPQ--GIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADA 886
+ MA + SE P G ++ L V L+ LG GAFG VY+G++ +
Sbjct: 905 MTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENV 964
Query: 887 AEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGG 946
++PVA+K L + + ++ +FL EA IMA H N++ L+ VC ++ +L+ G
Sbjct: 965 -KIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSSQ-MMLITQLMPLG 1022
Query: 947 DLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGP 1006
L +++R +R K + K LL S + KG YLE KR +HRD+AARN L+ +
Sbjct: 1023 CLLDYVRNNRDK------IGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPS- 1075
Query: 1007 GRVVKIADFGMARDIYR-ADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWE 1065
+VKI DFG+A+ + ++ YK G M PIKW+ E + VFT+K+DVW+FGV +WE
Sbjct: 1076 --LVKITDFGLAKLLSSDSNEYKAAGGKM-PIKWLALECIRNRVFTSKSDVWAFGVTIWE 1132
Query: 1066 VFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+ + G P+ +++ +L+ G +LE+P
Sbjct: 1133 LLTFGQRPHENIPAKDIPDLIEVGLKLEQP 1162
>UniRef50_UPI0000E47A46 Cluster: PREDICTED: similar to ret protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to ret protein - Strongylocentrotus purpuratus
Length = 531
Score = 156 bits (379), Expect = 3e-36
Identities = 88/247 (35%), Positives = 133/247 (53%), Gaps = 8/247 (3%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+ R LK+ K LG G FG VY+ + +PVAVK+L +T E DFL E
Sbjct: 281 EFDRSLLKIEKELGAGQFGIVYKAFAFGLNGIKEYVPVAVKSLRVNATPGMEEDFLNEIK 340
Query: 914 IMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA----LTMK 968
+M H NI+ +IG C P +++ E + GDL +FL + R R LT
Sbjct: 341 LMIDLGQHPNILQIIGCCTVHEPNYLITEYMKYGDLLHFLWKCREDKYRRQDSIFDLTQA 400
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+ L + +G Y+ R+ H D+AARN L+ G G VK++DFG+A DIY++ Y +
Sbjct: 401 NQLQICRQISRGMEYIFKTRYYHGDLAARNVLV---GEGLEVKVSDFGLADDIYQSGYKR 457
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
P+KW+ E G T ++DVWSFG++++E+++LG +PY G RE++ +
Sbjct: 458 LAPDKKRPVKWVSLETNTIGRCTIQSDVWSFGIVMYEIYTLGGVPYPGMDGREIISKLQE 517
Query: 1089 GGRLEKP 1095
G R+ KP
Sbjct: 518 GYRMPKP 524
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 156 bits (379), Expect = 3e-36
Identities = 93/244 (38%), Positives = 139/244 (56%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L+L LG G FG V +G+Y ++ + + VAVKTL E +S+ + EA
Sbjct: 351 ELDPKRLRLEHELGHGNFGSVVKGVYLLKNNKS--VAVAVKTLKEEDIPGQKSEIVKEAE 408
Query: 914 IMAKFNHANIVHLIGVCFDRHPRF-IVLELLAGGDLKNFLRESRPKPERASALTMKDLLL 972
IM+K +H NIV LIGV + P F +V+EL G L FL+++R + + D+L+
Sbjct: 409 IMSKLDHPNIVRLIGVT--QSPGFMLVMELAPQGPLHKFLKKNRN-------MNVLDILV 459
Query: 973 CSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI-YRADYYKKGG 1031
+ V +G YLE++ F+HRD+AARN L+ S VKI+DFGM+R + +YY+
Sbjct: 460 LMLQVDEGMNYLESQHFVHRDLAARNVLVVSEN---FVKISDFGMSRAMGVGNEYYRAER 516
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
P+KW PE F++K DVWS+G+ +WE S G PY G ++E + G R
Sbjct: 517 AGKWPLKWYAPECIYYHKFSSKGDVWSYGITMWEAVSYGGKPYQGMRGPVIVEKLESGYR 576
Query: 1092 LEKP 1095
L KP
Sbjct: 577 LPKP 580
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 156 bits (378), Expect = 4e-36
Identities = 92/254 (36%), Positives = 146/254 (57%), Gaps = 17/254 (6%)
Query: 858 ESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAK 917
E LK+ + +G+G FG VY+G Y R+ + E+ VA+KT+ + + L EA +M +
Sbjct: 448 ERLKMGRVIGEGEFGSVYEGTYTKRNGE--EIKVAIKTVRHEQI-ETSNAILKEAHVMMR 504
Query: 918 FNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDV 977
NH +V LIG+ R P +V EL+A G + N++ ++ S + + + +
Sbjct: 505 LNHHCVVKLIGLSKGR-PLLMVQELVALGSMLNYIILNKESINPNS-----EFKIWAAQI 558
Query: 978 CKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRA-DYYK--KGGKAM 1034
G YLE +RFIHRD+AARN LL S+ KI+DFG++R + +YY+ +GGK
Sbjct: 559 ACGMNYLEEQRFIHRDLAARNILLASQ---HQAKISDFGLSRALAADHEYYRALQGGK-- 613
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
P+KW PE+Y G F+ K+DVWSFGV +WE++S G +PY + ++++ G RL++
Sbjct: 614 WPLKWYAPESYNYGQFSHKSDVWSFGVAIWEMYSFGDVPYGELKGSDAIKIIEDGERLKQ 673
Query: 1095 PYGEGSEYHKFKRR 1108
P ++ RR
Sbjct: 674 PDACPDHIYEIMRR 687
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 155 bits (377), Expect = 5e-36
Identities = 93/247 (37%), Positives = 132/247 (53%), Gaps = 14/247 (5%)
Query: 851 GLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELST-GQAESDFL 909
G ++ L LG G FG V G+YR ++ + E+ A+K L + +++ L
Sbjct: 277 GPRRIEDSELSTQGELGAGTFGTVRLGVYRPKNGEP-EVQCALKYLKQSEELPNQKAEIL 335
Query: 910 MEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKD 969
EA MA +H NIV L G+C P +V+EL G L FLR+ RP L M
Sbjct: 336 READAMAALDHCNIVRLFGICVG-DPICLVMELARQGPLNKFLRK-RPTFPVIKILNM-- 391
Query: 970 LLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYR-ADYYK 1028
++ V +G YLE RF+HRD+AARN L+ VKI+DFGM+R I ++YYK
Sbjct: 392 ----ALQVSRGMAYLEEVRFVHRDLAARNVLVVDDDN---VKISDFGMSRAIGAGSEYYK 444
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
P+KW PE F +K+DVWS+GV +WE FS G PY G +++M+++ G
Sbjct: 445 AETAGRWPLKWYAPECIYYAKFDSKSDVWSYGVTVWEAFSFGAKPYAGLKGQDIMQMLEG 504
Query: 1089 GGRLEKP 1095
RL+ P
Sbjct: 505 NQRLDSP 511
>UniRef50_Q4H3N2 Cluster: Epidermal growth factor receptor; n=1; Ciona
intestinalis|Rep: Epidermal growth factor receptor -
Ciona intestinalis (Transparent sea squirt)
Length = 878
Score = 155 bits (377), Expect = 5e-36
Identities = 96/264 (36%), Positives = 149/264 (56%), Gaps = 19/264 (7%)
Query: 840 ESFLPQGI--DVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSA--DAAEMPVAVKT 895
E P G+ + L V L++ K LG GAFG V++G + A + ++PVA+K
Sbjct: 101 EPMTPSGVAPNQAQLRIVKEAELRIGKILGSGAFGTVHKGYWIPDLAPRERVKVPVAIKV 160
Query: 896 LPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRES 955
L + S+ A ++ L EA +MA H N+V L+G+ + ++ +L+ G+L ++R++
Sbjct: 161 LRDESSQVASNEILDEAFVMASCEHPNLVRLLGISLSQRI-MLITQLMPLGNLLEYVRDN 219
Query: 956 RPKPERASALTMKDLLLCSVDVCKGCRYL-ETKRFIHRDIAARNCLLTSRGPGRVVKIAD 1014
+ + + LL S+ + KG +YL E K +HRD+AARN L+ S P V +I D
Sbjct: 220 KDN------IGSQHLLNWSLQIAKGMKYLSEEKHLVHRDLAARNVLVKS--PNHV-RITD 270
Query: 1015 FGMAR--DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVM 1072
FG+A+ D+ Y +GGK +PIKW+ E+ +FT K+DVWSFGV +WE+ + G
Sbjct: 271 FGLAKLLDVKEDVYRAEGGK--MPIKWLALESIQHRIFTQKSDVWSFGVTMWELMTFGKK 328
Query: 1073 PYTGCANREVMELVSGGGRLEKPY 1096
PY REV L+ G RL +PY
Sbjct: 329 PYESVPAREVHTLLERGERLPQPY 352
>UniRef50_O76385 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 903
Score = 155 bits (377), Expect = 5e-36
Identities = 103/268 (38%), Positives = 139/268 (51%), Gaps = 41/268 (15%)
Query: 864 KALGQGAFGEVYQGLY-----RHRSAD---------AAEMPVAVKTLPELSTGQAESDFL 909
K LG GAFG VY G H+ A+ A VAVK LPE + ++ +FL
Sbjct: 547 KKLGSGAFGAVYLGKLIGKSLAHKDANSPLGINLMRAENCQVAVKMLPEYADEMSKHEFL 606
Query: 910 MEAAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRES------------- 955
E A+M H +V+++ + P +V+E GDL FLRE
Sbjct: 607 REIALMKTLGYHERLVNMLACVTESEPLCLVVEYCDNGDLLKFLRERCKYMMKLDDLGIN 666
Query: 956 -RPKPERAS-----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRV 1009
PE + +T+K LL +V + G YL K F+HRD+AARN L+ G
Sbjct: 667 YHDPPENENYDTNMIVTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHE---GTA 723
Query: 1010 VKIADFGMARDIY--RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVF 1067
KI DFG+ R IY ++ Y KGGK LP+KWM PEA F+ K+D+WSFG+LL+EV
Sbjct: 724 CKIGDFGLCRYIYADQSQYKSKGGK--LPLKWMSPEAIRHYEFSIKSDIWSFGILLFEVI 781
Query: 1068 SLGVMPYTGCANREVMELVSGGGRLEKP 1095
+LG PY G +V+ + GGGR+EKP
Sbjct: 782 TLGGSPYPGMPPEDVLPFLEGGGRIEKP 809
>UniRef50_Q9XVQ7 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 442
Score = 155 bits (376), Expect = 6e-36
Identities = 100/270 (37%), Positives = 154/270 (57%), Gaps = 22/270 (8%)
Query: 837 YGSESFLPQ-GIDVRGLPQ---VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVA 892
Y ++S L G D+R Q + E++ L +G+G FG VY+G R R +PVA
Sbjct: 109 YSTQSLLQLIGSDLRQSLQGLLLPSEAVVLETIVGKGYFGNVYRG--RMRDPAGRLIPVA 166
Query: 893 VKTLP-ELSTGQAESD-FLMEAAIMAKFNHANIVHLIGVCFDRHPR-FIVLELLAGGDLK 949
VKTL E + A + FL E +M +H +++ L+G+ ++VL + GGDLK
Sbjct: 167 VKTLKGERARDIAHIEKFLREGVVMKHLDHPHVLSLLGISISPAGNPWVVLPYMEGGDLK 226
Query: 950 NFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRV 1009
++ + P RA L + +LL + V +G YL + F+HRD+AARNC++++ R+
Sbjct: 227 TYIAD----PNRA--LCVLELLDFAHQVAQGMSYLAAQHFVHRDLAARNCMISA---DRI 277
Query: 1010 VKIADFGMARDIYRADYY---KKGGKAMLPIKWMPPEAYIDG-VFTTKTDVWSFGVLLWE 1065
VK+ADFG+A D+ + Y + G A LP+KW+ PE+ D VF++ TDVWSFGVL+WE
Sbjct: 278 VKVADFGLAVDLLDKESYIDESETGPARLPLKWLAPESLRDRRVFSSATDVWSFGVLMWE 337
Query: 1066 VFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+ + PY +N +V + G RL +P
Sbjct: 338 LLTRAASPYGEVSNTKVRHYLETGMRLPQP 367
>UniRef50_Q6VU50 Cluster: Eph receptor; n=3; Endopterygota|Rep: Eph
receptor - Manduca sexta (Tobacco hawkmoth) (Tobacco
hornworm)
Length = 1011
Score = 155 bits (376), Expect = 6e-36
Identities = 93/245 (37%), Positives = 136/245 (55%), Gaps = 15/245 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + + +G G FG+V +G + S E+ VA+KTL ST +A DFL EA+
Sbjct: 641 EIDASCITIEAIIGGGEFGDVCRGKLKLASC-GQEIDVAIKTLKPGSTERARRDFLAEAS 699
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +F H N++ L GV +P I+ E + G L FLR + K L + +L
Sbjct: 700 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK---FMVLQLVGMLR- 755
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYR-AD--YYKKG 1030
+ G +YL +IHRD+AARN L+ S V KIADFG++R+I AD Y +G
Sbjct: 756 --GIATGMQYLSEMNYIHRDLAARNVLVNSH---LVCKIADFGLSREIESTADGAYTTRG 810
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
GK +P++W PEA FT+ +DVWS G++ WEV S G PY +N++V++ + G
Sbjct: 811 GK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 868
Query: 1091 RLEKP 1095
RL P
Sbjct: 869 RLPAP 873
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 155 bits (376), Expect = 6e-36
Identities = 104/241 (43%), Positives = 140/241 (58%), Gaps = 26/241 (10%)
Query: 858 ESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAK 917
+ L L +G+G FG V QG Y + VAVK + T QA FL E A+M K
Sbjct: 233 QHLTLGAQIGEGEFGAVLQGEYLGQK-------VAVKNIKCDVTAQA---FLDETAVMTK 282
Query: 918 FNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDV 977
H N+V L+GV + +IV+E ++ G+L NFLR RA T + LL S+ V
Sbjct: 283 MQHENLVRLLGVILHQG-LYIVMEHVSKGNLVNFLRTRG----RALVNTAQ-LLQFSLHV 336
Query: 978 CKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG-GKAMLP 1036
+G YLE+K+ +HRD+AARN L++ V K++DFG+A+ A+ +KG + LP
Sbjct: 337 AEGMEYLESKKLVHRDLAARNILVSE---DLVAKVSDFGLAK----AE--RKGLDSSRLP 387
Query: 1037 IKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKPY 1096
+KW PEA G FT+K+DVWSFGVLLWEVFS G PY + +EV E V G R+E P
Sbjct: 388 VKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPE 447
Query: 1097 G 1097
G
Sbjct: 448 G 448
>UniRef50_Q4H3M7 Cluster: Ephrin receptor; n=3; Ciona|Rep: Ephrin
receptor - Ciona intestinalis (Transparent sea squirt)
Length = 1006
Score = 155 bits (375), Expect = 8e-36
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 24/248 (9%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + + + + +G+G FGEV +G + ++ VA+KTL Q SDFL EA+
Sbjct: 640 EIDFKLVNIEQVIGRGEFGEVCKGTFFNKC-------VAIKTLKVGYNTQERSDFLGEAS 692
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM +F+H N++ L GV P I+ E + G L FLR K A + ++LL
Sbjct: 693 IMGQFDHPNVIRLEGVVTKSRPLMIITEFMENGSLDAFLRNQEGKIPSAQ---LTEMLL- 748
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD------YY 1027
+ +G YL ++HRD+AARN L+ S V K++DFG++R + + + Y
Sbjct: 749 --SIAQGMEYLSNMGYVHRDLAARNILVNSN---LVCKVSDFGLSRVLEQLEEDDVAMYT 803
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
+GG M+PI+W PEA F+T +DVWSFG+++WEV S G PY +N++V++ V
Sbjct: 804 TRGG--MIPIRWTSPEAITMRTFSTSSDVWSFGIVMWEVMSFGERPYWEMSNQDVVQFVD 861
Query: 1088 GGGRLEKP 1095
G RL P
Sbjct: 862 SGYRLPPP 869
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.321 0.137 0.435
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,280,218,578
Number of Sequences: 1657284
Number of extensions: 55548655
Number of successful extensions: 138432
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1948
Number of HSP's successfully gapped in prelim test: 7008
Number of HSP's that attempted gapping in prelim test: 120678
Number of HSP's gapped (non-prelim): 13267
length of query: 1116
length of database: 575,637,011
effective HSP length: 109
effective length of query: 1007
effective length of database: 394,993,055
effective search space: 397758006385
effective search space used: 397758006385
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 78 (35.5 bits)
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