Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000152-TA|BGIBMGA000152-PA|IPR011009|Protein
kinase-like, IPR002172|Low density lipoprotein-receptor, class A,
IPR000998|MAM, IPR000719|Protein kinase, IPR008266|Tyrosine protein
kinase, active site, IPR001245|Tyrosine protein kinase
(1116 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 346 3e-94
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 345 7e-94
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 345 7e-94
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 345 7e-94
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 345 7e-94
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 345 7e-94
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 345 7e-94
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 345 7e-94
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 345 7e-94
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 328 5e-89
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 328 5e-89
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 326 3e-88
Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus o... 269 3e-71
Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus o... 269 3e-71
M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein. 269 3e-71
M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3 (rea... 269 3e-71
M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein. 269 3e-71
AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus... 269 3e-71
AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus... 269 3e-71
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 243 3e-63
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 243 3e-63
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 243 3e-63
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 243 3e-63
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 243 3e-63
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 237 1e-61
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 237 1e-61
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 237 1e-61
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 237 1e-61
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 232 6e-60
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 232 6e-60
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 203 3e-51
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 203 3e-51
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 203 3e-51
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 203 3e-51
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 203 3e-51
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 203 3e-51
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 203 3e-51
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 203 3e-51
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 200 3e-50
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 200 3e-50
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 199 4e-50
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 199 4e-50
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 199 4e-50
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 199 4e-50
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 199 4e-50
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 199 4e-50
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 199 4e-50
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 199 4e-50
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 199 5e-50
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 198 7e-50
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 197 2e-49
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 197 2e-49
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 197 2e-49
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 197 2e-49
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 197 2e-49
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 197 2e-49
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 197 2e-49
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 197 2e-49
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 196 4e-49
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 196 4e-49
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 196 4e-49
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 196 4e-49
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 196 4e-49
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 196 4e-49
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 196 4e-49
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 196 4e-49
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 196 4e-49
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 196 4e-49
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 194 1e-48
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 194 1e-48
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 194 1e-48
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 194 1e-48
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 194 1e-48
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 194 1e-48
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 194 1e-48
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 194 1e-48
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 194 1e-48
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 194 1e-48
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 194 1e-48
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 194 1e-48
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 194 1e-48
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 194 1e-48
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 194 1e-48
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 194 1e-48
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 194 1e-48
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 194 1e-48
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 194 1e-48
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 194 1e-48
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 194 1e-48
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 194 1e-48
AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein. 194 1e-48
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 194 1e-48
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 194 1e-48
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 194 1e-48
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 194 1e-48
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 194 1e-48
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 194 1e-48
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 194 1e-48
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 194 1e-48
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 194 1e-48
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 194 1e-48
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 194 1e-48
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 194 1e-48
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 194 1e-48
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 194 1e-48
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 194 1e-48
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 194 1e-48
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 194 1e-48
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 194 1e-48
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 194 2e-48
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 194 2e-48
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 192 6e-48
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 191 1e-47
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 191 1e-47
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 191 1e-47
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 191 1e-47
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 191 1e-47
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 191 1e-47
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 191 1e-47
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 191 1e-47
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 191 1e-47
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 191 1e-47
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 191 1e-47
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 191 1e-47
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 191 1e-47
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 191 1e-47
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 191 1e-47
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 191 1e-47
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 191 1e-47
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 190 2e-47
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 190 2e-47
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 190 2e-47
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 190 2e-47
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 190 2e-47
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 190 2e-47
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 190 2e-47
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 188 7e-47
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 188 1e-46
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 188 1e-46
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 187 2e-46
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 186 3e-46
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 186 3e-46
S76475-1|AAB33111.1| 839|Homo sapiens trkC protein. 184 2e-45
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 184 2e-45
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 184 2e-45
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 184 2e-45
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 184 2e-45
AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein. 184 2e-45
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 184 2e-45
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 183 3e-45
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 183 3e-45
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 183 3e-45
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 183 4e-45
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 183 4e-45
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 183 4e-45
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 183 4e-45
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 183 4e-45
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 183 4e-45
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 183 4e-45
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 183 4e-45
AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein pr... 183 4e-45
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 183 4e-45
BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein. 181 1e-44
BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein. 181 1e-44
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 181 1e-44
AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein. 181 1e-44
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 179 6e-44
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 178 8e-44
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 178 8e-44
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 178 8e-44
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 177 1e-43
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 177 1e-43
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 177 1e-43
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 177 1e-43
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 177 1e-43
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 177 1e-43
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 177 1e-43
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 177 1e-43
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 177 1e-43
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 177 1e-43
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 177 2e-43
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 177 2e-43
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 177 2e-43
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 177 2e-43
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 177 2e-43
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 177 2e-43
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 177 2e-43
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 177 2e-43
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 177 2e-43
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 177 2e-43
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 177 2e-43
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 177 2e-43
X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein. 176 3e-43
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 176 3e-43
X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto... 176 3e-43
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 176 3e-43
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 176 3e-43
M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA ... 176 4e-43
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 176 4e-43
BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene prot... 176 4e-43
M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 175 1e-42
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 173 4e-42
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 173 4e-42
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 173 4e-42
AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec... 173 4e-42
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 173 4e-42
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 173 4e-42
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 172 7e-42
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 171 9e-42
U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein. 171 9e-42
S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal ty... 171 9e-42
L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase pro... 171 9e-42
BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine ... 171 9e-42
BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine ... 171 9e-42
AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens ... 171 9e-42
AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine ... 171 9e-42
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 171 1e-41
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 171 1e-41
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 171 1e-41
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 171 1e-41
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 171 1e-41
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 171 1e-41
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 171 1e-41
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 171 1e-41
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 169 5e-41
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 169 6e-41
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 169 6e-41
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 169 6e-41
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 169 6e-41
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 169 6e-41
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 168 8e-41
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 168 8e-41
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 168 8e-41
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 168 8e-41
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 168 8e-41
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 168 8e-41
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 168 8e-41
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 168 8e-41
BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein. 168 8e-41
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 168 8e-41
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 168 8e-41
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 168 8e-41
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 168 8e-41
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 168 8e-41
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 168 8e-41
M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor pr... 168 1e-40
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 168 1e-40
BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine kinas... 168 1e-40
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 168 1e-40
AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine kinas... 168 1e-40
AL928802-1|CAI17302.1| 704|Homo sapiens receptor tyrosine kinas... 168 1e-40
AL591214-1|CAH71099.1| 704|Homo sapiens receptor tyrosine kinas... 168 1e-40
AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine kinas... 168 1e-40
AL583841-1|CAI15693.1| 704|Homo sapiens receptor tyrosine kinas... 168 1e-40
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 168 1e-40
AL391219-1|CAH70208.1| 943|Homo sapiens receptor tyrosine kinas... 168 1e-40
AF294796-1|AAG01184.2| 910|Homo sapiens ROR2 protein protein. 168 1e-40
AB209154-1|BAD92391.1| 919|Homo sapiens Tyrosine-protein kinase... 168 1e-40
X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein. 167 2e-40
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 166 3e-40
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 163 2e-39
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 163 2e-39
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 163 2e-39
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 163 2e-39
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 163 2e-39
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 163 3e-39
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 163 3e-39
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 162 5e-39
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 162 5e-39
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 162 5e-39
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 162 7e-39
U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase ... 162 7e-39
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 162 7e-39
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 162 7e-39
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 162 7e-39
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 161 1e-38
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 161 1e-38
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 161 1e-38
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 161 1e-38
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 161 1e-38
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 161 1e-38
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 161 1e-38
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 161 1e-38
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 161 1e-38
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 161 1e-38
M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene pr... 161 2e-38
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 161 2e-38
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 161 2e-38
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 161 2e-38
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 159 4e-38
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 159 4e-38
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 159 4e-38
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 159 4e-38
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 159 4e-38
L08961-1|AAC41766.1| 600|Homo sapiens tyrosine kinase protein. 159 7e-38
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 159 7e-38
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 159 7e-38
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 159 7e-38
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 159 7e-38
X98208-1|CAA66871.1| 913|Homo sapiens discoidin receptor tyrosi... 158 9e-38
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 158 9e-38
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 158 9e-38
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 158 9e-38
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 158 9e-38
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 158 9e-38
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 158 1e-37
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 158 1e-37
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 158 1e-37
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 158 1e-37
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 158 1e-37
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 158 1e-37
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 158 1e-37
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 158 1e-37
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 158 1e-37
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 158 1e-37
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 158 1e-37
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 158 1e-37
AL662870-7|CAI18442.1| 913|Homo sapiens discoidin domain recept... 158 1e-37
AL662870-6|CAI18441.1| 876|Homo sapiens discoidin domain recept... 158 1e-37
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 158 1e-37
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 158 1e-37
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 158 1e-37
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 158 1e-37
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 158 1e-37
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 158 1e-37
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 157 2e-37
X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein. 157 2e-37
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 157 2e-37
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 157 2e-37
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 157 2e-37
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 157 2e-37
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 157 2e-37
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 157 2e-37
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 157 2e-37
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 157 3e-37
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 157 3e-37
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 157 3e-37
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 157 3e-37
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 157 3e-37
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 156 5e-37
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 156 5e-37
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 156 5e-37
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 155 6e-37
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 155 6e-37
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 155 6e-37
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 155 6e-37
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 155 6e-37
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 155 6e-37
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 155 8e-37
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 155 8e-37
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 155 8e-37
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 155 8e-37
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 155 8e-37
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 155 8e-37
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 155 1e-36
X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA frag... 154 1e-36
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 154 1e-36
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 154 1e-36
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 154 1e-36
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 154 1e-36
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 154 1e-36
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 154 1e-36
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 154 1e-36
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 154 1e-36
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 154 1e-36
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 154 1e-36
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 154 1e-36
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 154 1e-36
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 154 1e-36
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 154 1e-36
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 153 4e-36
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 153 4e-36
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 153 4e-36
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 153 4e-36
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 153 4e-36
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 153 4e-36
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 153 4e-36
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 153 4e-36
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 153 4e-36
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 153 4e-36
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 153 4e-36
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 153 4e-36
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 153 4e-36
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 151 1e-35
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 151 1e-35
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 151 1e-35
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 151 1e-35
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 151 1e-35
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 151 2e-35
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 151 2e-35
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 150 3e-35
AL662870-9|CAM25688.1| 377|Homo sapiens discoidin domain recept... 149 4e-35
AL662854-9|CAM24839.1| 377|Homo sapiens discoidin domain recept... 149 4e-35
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 149 5e-35
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 149 5e-35
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 149 5e-35
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 148 1e-34
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 147 2e-34
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 146 5e-34
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 145 7e-34
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 145 7e-34
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 145 7e-34
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 145 7e-34
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 145 7e-34
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 144 1e-33
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 144 1e-33
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 144 1e-33
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 144 1e-33
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 144 1e-33
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 144 2e-33
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 144 2e-33
X69878-1|CAA49505.1| 1298|Homo sapiens protein ( H.sapiens Flt4 ... 143 4e-33
AY233383-1|AAO89505.1| 1363|Homo sapiens VEGFR3 long form protein. 143 4e-33
AY233382-1|AAO89504.1| 1298|Homo sapiens VEGFR3 short form protein. 143 4e-33
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 143 4e-33
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 142 5e-33
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 142 5e-33
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 142 5e-33
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 142 5e-33
Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine ki... 142 8e-33
X68203-1|CAA48290.1| 1304|Homo sapiens FTL4 protein. 142 8e-33
U43143-1|AAA85215.1| 1298|Homo sapiens Flt4 protein. 142 8e-33
U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein ... 142 8e-33
M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein pro... 142 8e-33
BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine ki... 142 8e-33
AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes va... 142 8e-33
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 141 1e-32
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 141 1e-32
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 141 1e-32
L36162-1|AAA35487.1| 160|Homo sapiens receptor tyrosine kinase ... 140 2e-32
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 140 2e-32
AC004416-1|AAF66137.2| 583|Homo sapiens unknown protein. 140 3e-32
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 139 6e-32
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 139 6e-32
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 139 6e-32
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 139 6e-32
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 139 6e-32
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 139 6e-32
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 139 6e-32
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 139 6e-32
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 139 6e-32
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 138 8e-32
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 138 8e-32
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 138 8e-32
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 138 8e-32
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 138 8e-32
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 138 8e-32
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 138 8e-32
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 138 8e-32
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 137 2e-31
BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein. 137 2e-31
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 136 3e-31
U38894-1|AAC50714.1| 388|Homo sapiens tyrosine kinase t-Ror1 pr... 136 3e-31
X96588-1|CAA65406.1| 577|Homo sapiens receptor tyrosine kinase ... 136 5e-31
X69970-1|CAA49591.1| 607|Homo sapiens h-ryk protein. 136 5e-31
AL591024-3|CAH70634.1| 996|Homo sapiens fms-related tyrosine ki... 136 5e-31
AL445262-1|CAI17231.1| 996|Homo sapiens fms-related tyrosine ki... 136 5e-31
AL356915-1|CAI12447.1| 996|Homo sapiens fms-related tyrosine ki... 136 5e-31
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 135 7e-31
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 135 7e-31
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 135 7e-31
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 135 7e-31
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 135 7e-31
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 135 7e-31
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 135 7e-31
AB067470-1|BAB67776.1| 1480|Homo sapiens KIAA1883 protein protein. 135 7e-31
X03663-1|CAA27300.1| 972|Homo sapiens protein ( Human mRNA for ... 133 4e-30
U63963-1|AAB51696.1| 972|Homo sapiens CSF-1 receptor protein. 133 4e-30
BC047521-1|AAH47521.1| 972|Homo sapiens colony stimulating fact... 133 4e-30
M22734-1|AAA60048.1| 1089|Homo sapiens platelet-derived growth f... 132 5e-30
M21574-1|AAA96715.1| 1089|Homo sapiens platelet-derived growth f... 132 5e-30
D50017-1|BAA08742.1| 1089|Homo sapiens alpha-platelet-derived gr... 132 5e-30
AY229892-1|AAP69563.1| 849|Homo sapiens FIP1L1/PDGFRA fusion pr... 132 5e-30
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 132 7e-30
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 131 1e-29
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 131 1e-29
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 131 1e-29
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 131 1e-29
AB209050-1|BAD92287.1| 551|Homo sapiens fms-related tyrosine ki... 131 1e-29
M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal... 131 2e-29
M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal... 131 2e-29
BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic... 131 2e-29
S59184-1|AAB26341.1| 606|Homo sapiens RYK protein. 130 3e-29
BC035782-1|AAH35782.1| 661|Homo sapiens TNK1 protein protein. 130 3e-29
AF097738-1|AAC99412.1| 661|Homo sapiens non-receptor tyosine ki... 130 3e-29
L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kina... 130 4e-29
DQ836395-1|ABI53804.1| 556|Homo sapiens N2idVEGFR-1 protein. 130 4e-29
DQ836394-1|ABI53803.1| 556|Homo sapiens idVEGFR-1 protein. 130 4e-29
BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein. 130 4e-29
AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens ... 130 4e-29
AK131529-1|BAD18667.1| 879|Homo sapiens protein ( Homo sapiens ... 129 5e-29
>AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplastic
lymphoma kinase fusion protein protein.
Length = 701
Score = 346 bits (850), Expect = 3e-94
Identities = 168/304 (55%), Positives = 216/304 (71%), Gaps = 10/304 (3%)
Query: 793 NRYQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
N Y++K + QA Q + E +L +LR + D +NP+Y F + +
Sbjct: 138 NVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISD 188
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
L +V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLME
Sbjct: 189 LKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLME 248
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLL 971
A I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 249 ALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLL 308
Query: 972 LCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGG 1031
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG
Sbjct: 309 HVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGG 368
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
AMLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR
Sbjct: 369 CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGR 428
Query: 1092 LEKP 1095
++ P
Sbjct: 429 MDPP 432
>U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinase
receptor protein.
Length = 1620
Score = 345 bits (847), Expect = 7e-94
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 1059 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 1109
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 1110 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 1169
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 1170 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 1229
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 1230 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 1289
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 1290 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 1349
Query: 1094 KP 1095
P
Sbjct: 1350 PP 1351
Score = 95.9 bits (228), Expect = 7e-19
Identities = 93/372 (25%), Positives = 152/372 (40%), Gaps = 36/372 (9%)
Query: 277 CMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFSTKDKGEN-WYRASIFLPNVTRRY 335
C +R + G G++S+ +VE VW +G + W + L +V+ R+
Sbjct: 548 CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRF 607
Query: 336 YLQFKTRMGMRIYSDSAIDDFSMSPECFGLNVDPEE------------LGDYNYYDPVFD 383
+LQ G + A D+ S+S +C+ L + E+ L + N +
Sbjct: 608 WLQMVAWWGQGSRAIVAFDNISISLDCY-LTISGEDKILQNTAPKSRNLFERNPNKELKP 666
Query: 384 EKTTPHKD--FTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVW 441
+ +P + F V++ FT CGASG +GP Q C+ AY N+ + V V P G+Q+W
Sbjct: 667 GENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIW 726
Query: 442 EVPEEGLYTIIA-TXXXXXXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINACKKT 500
+VP Y+I HG + L + +++Y+L+GQQG +AC T
Sbjct: 727 KVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPST 786
Query: 501 LSAQESQECSRKPSNESLQVFTSKTHEVRNTHV-IDXXXXXXXXTFVFLMDKEGRPFPLV 559
+ +K V + R+ H T+VF M K+G P PL+
Sbjct: 787 ------NQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKM-KDGVPVPLI 839
Query: 560 VAXXXXXISVGIFRDDGSQHGKPHTNSTPESGYMYGQPDKTSEYVVLGTGAGGGWVARSG 619
+A + G D + H + N++ G + G G GGGW +
Sbjct: 840 IAAGGGGRAYGAKTD--TFHPERLENNSSVLG-LNGNSG--------AAGGGGGWNDNTS 888
Query: 620 PITPGSERVRGA 631
+ G GA
Sbjct: 889 LLWAGKSLQEGA 900
Score = 54.8 bits (126), Expect = 2e-06
Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 12/168 (7%)
Query: 6 VKSPPFRGLWEFCKFEALLHQRMMQNAS-IRLISESTISEVQWILQEVAGNNAENWYPMR 64
+ SP R E C +H+ + + I + + + +L G + W ++
Sbjct: 333 ILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAAREILLMPTPGKHG--WTVLQ 390
Query: 65 FMIGKVQQEVRIIIEITRPNYVSLAQPLPHIAIDNIRMIDCVPEPPVYNGECNAGQLKCK 124
IG+ R+ +E SL+ A+D + +C G A Q
Sbjct: 391 GRIGRPDNPFRVALEYISSGNRSLS------AVDFFALKNC--SEGTSPGSKMALQSSFT 442
Query: 125 IMNRESCIKLHQVCDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGF 172
N + ++L Q CD +DC G DE + C K+P G YCNFE CG+
Sbjct: 443 CWNG-TVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGW 489
>U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinase
protein.
Length = 1620
Score = 345 bits (847), Expect = 7e-94
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 1059 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 1109
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 1110 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 1169
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 1170 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 1229
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 1230 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 1289
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 1290 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 1349
Query: 1094 KP 1095
P
Sbjct: 1350 PP 1351
Score = 95.9 bits (228), Expect = 7e-19
Identities = 93/372 (25%), Positives = 152/372 (40%), Gaps = 36/372 (9%)
Query: 277 CMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFSTKDKGEN-WYRASIFLPNVTRRY 335
C +R + G G++S+ +VE VW +G + W + L +V+ R+
Sbjct: 548 CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRF 607
Query: 336 YLQFKTRMGMRIYSDSAIDDFSMSPECFGLNVDPEE------------LGDYNYYDPVFD 383
+LQ G + A D+ S+S +C+ L + E+ L + N +
Sbjct: 608 WLQMVAWWGQGSRAIVAFDNISISLDCY-LTISGEDKILQNTAPKSRNLFERNPNKELKP 666
Query: 384 EKTTPHKD--FTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVW 441
+ +P + F V++ FT CGASG +GP Q C+ AY N+ + V V P G+Q+W
Sbjct: 667 GENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIW 726
Query: 442 EVPEEGLYTIIA-TXXXXXXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINACKKT 500
+VP Y+I HG + L + +++Y+L+GQQG +AC T
Sbjct: 727 KVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPST 786
Query: 501 LSAQESQECSRKPSNESLQVFTSKTHEVRNTHV-IDXXXXXXXXTFVFLMDKEGRPFPLV 559
+ +K V + R+ H T+VF M K+G P PL+
Sbjct: 787 ------NQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKM-KDGVPVPLI 839
Query: 560 VAXXXXXISVGIFRDDGSQHGKPHTNSTPESGYMYGQPDKTSEYVVLGTGAGGGWVARSG 619
+A + G D + H + N++ G + G G GGGW +
Sbjct: 840 IAAGGGGRAYGAKTD--TFHPERLENNSSVLG-LNGNSG--------AAGGGGGWNDNTS 888
Query: 620 PITPGSERVRGA 631
+ G GA
Sbjct: 889 LLWAGKSLQEGA 900
Score = 54.8 bits (126), Expect = 2e-06
Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 12/168 (7%)
Query: 6 VKSPPFRGLWEFCKFEALLHQRMMQNAS-IRLISESTISEVQWILQEVAGNNAENWYPMR 64
+ SP R E C +H+ + + I + + + +L G + W ++
Sbjct: 333 ILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAAREILLMPTPGKHG--WTVLQ 390
Query: 65 FMIGKVQQEVRIIIEITRPNYVSLAQPLPHIAIDNIRMIDCVPEPPVYNGECNAGQLKCK 124
IG+ R+ +E SL+ A+D + +C G A Q
Sbjct: 391 GRIGRPDNPFRVALEYISSGNRSLS------AVDFFALKNC--SEGTSPGSKMALQSSFT 442
Query: 125 IMNRESCIKLHQVCDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGF 172
N + ++L Q CD +DC G DE + C K+P G YCNFE CG+
Sbjct: 443 CWNG-TVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGW 489
>U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic
lymphoma kinase fusion protein protein.
Length = 680
Score = 345 bits (847), Expect = 7e-94
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 119 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 169
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 170 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 229
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 230 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 289
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 290 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 349
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 350 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 409
Query: 1094 KP 1095
P
Sbjct: 410 PP 411
>D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein.
Length = 680
Score = 345 bits (847), Expect = 7e-94
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 119 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 169
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 170 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 229
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 230 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 289
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 290 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 349
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 350 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 409
Query: 1094 KP 1095
P
Sbjct: 410 PP 411
>AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplastic
large cell lymphoma kinase extra long form protein.
Length = 803
Score = 345 bits (847), Expect = 7e-94
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 242 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 292
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 293 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 352
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 353 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 412
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 413 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 472
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 473 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 532
Query: 1094 KP 1095
P
Sbjct: 533 PP 534
>AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplastic
lymphoma kinase (Ki-1) fusion protein long form protein.
Length = 756
Score = 345 bits (847), Expect = 7e-94
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 195 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 245
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 246 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 305
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 306 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 365
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 366 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 425
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 426 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 485
Query: 1094 KP 1095
P
Sbjct: 486 PP 487
>AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein.
Length = 1192
Score = 345 bits (847), Expect = 7e-94
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 631 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 681
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 682 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 741
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 742 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 801
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 802 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 861
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 862 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 921
Query: 1094 KP 1095
P
Sbjct: 922 PP 923
Score = 95.9 bits (228), Expect = 7e-19
Identities = 93/372 (25%), Positives = 152/372 (40%), Gaps = 36/372 (9%)
Query: 277 CMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFSTKDKGEN-WYRASIFLPNVTRRY 335
C +R + G G++S+ +VE VW +G + W + L +V+ R+
Sbjct: 120 CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRF 179
Query: 336 YLQFKTRMGMRIYSDSAIDDFSMSPECFGLNVDPEE------------LGDYNYYDPVFD 383
+LQ G + A D+ S+S +C+ L + E+ L + N +
Sbjct: 180 WLQMVAWWGQGSRAIVAFDNISISLDCY-LTISGEDKILQNTAPKSRNLFERNPNKELKP 238
Query: 384 EKTTPHKD--FTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVW 441
+ +P + F V++ FT CGASG +GP Q C+ AY N+ + V V P G+Q+W
Sbjct: 239 GENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIW 298
Query: 442 EVPEEGLYTIIA-TXXXXXXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINACKKT 500
+VP Y+I HG + L + +++Y+L+GQQG +AC T
Sbjct: 299 KVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPST 358
Query: 501 LSAQESQECSRKPSNESLQVFTSKTHEVRNTHV-IDXXXXXXXXTFVFLMDKEGRPFPLV 559
+ +K V + R+ H T+VF M K+G P PL+
Sbjct: 359 ------NQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKM-KDGVPVPLI 411
Query: 560 VAXXXXXISVGIFRDDGSQHGKPHTNSTPESGYMYGQPDKTSEYVVLGTGAGGGWVARSG 619
+A + G D + H + N++ G + G G GGGW +
Sbjct: 412 IAAGGGGRAYGAKTD--TFHPERLENNSSVLG-LNGNSG--------AAGGGGGWNDNTS 460
Query: 620 PITPGSERVRGA 631
+ G GA
Sbjct: 461 LLWAGKSLQEGA 472
Score = 53.2 bits (122), Expect = 5e-06
Identities = 20/41 (48%), Positives = 26/41 (63%)
Query: 132 IKLHQVCDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGF 172
++L Q CD +DC G DE + C K+P G YCNFE CG+
Sbjct: 21 LQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGW 61
>AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kinase
Ki-1 variant protein.
Length = 1626
Score = 345 bits (847), Expect = 7e-94
Identities = 167/302 (55%), Positives = 215/302 (71%), Gaps = 10/302 (3%)
Query: 795 YQKKREARQA-QKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLP 853
Y++K + QA Q + E +L +LR + D +NP+Y F + + L
Sbjct: 1065 YRRKHQELQAMQMELQSPEYKLSKLRTSTIMTD------YNPNY---CFAGKTSSISDLK 1115
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V R+++ L++ LG GAFGEVY+G D + + VAVKTLPE+ + Q E DFLMEA
Sbjct: 1116 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEAL 1175
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KFNH NIV IGV PRFI+LEL+AGGDLK+FLRE+RP+P + S+L M DLL
Sbjct: 1176 IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV 1235
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ GC+YLE FIHRDIAARNCLLT GPGRV KI DFGMARDIYRA YY+KGG A
Sbjct: 1236 ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCA 1295
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
MLP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY +N+EV+E V+ GGR++
Sbjct: 1296 MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMD 1355
Query: 1094 KP 1095
P
Sbjct: 1356 PP 1357
Score = 95.9 bits (228), Expect = 7e-19
Identities = 93/372 (25%), Positives = 152/372 (40%), Gaps = 36/372 (9%)
Query: 277 CMVRFYYQQNGRNYGSLSVDVVELTARGNISTSVWFSTKDKGEN-WYRASIFLPNVTRRY 335
C +R + G G++S+ +VE VW +G + W + L +V+ R+
Sbjct: 554 CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRF 613
Query: 336 YLQFKTRMGMRIYSDSAIDDFSMSPECFGLNVDPEE------------LGDYNYYDPVFD 383
+LQ G + A D+ S+S +C+ L + E+ L + N +
Sbjct: 614 WLQMVAWWGQGSRAIVAFDNISISLDCY-LTISGEDKILQNTAPKSRNLFERNPNKELKP 672
Query: 384 EKTTPHKD--FTGRVYYRFTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVW 441
+ +P + F V++ FT CGASG +GP Q C+ AY N+ + V V P G+Q+W
Sbjct: 673 GENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIW 732
Query: 442 EVPEEGLYTIIA-TXXXXXXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINACKKT 500
+VP Y+I HG + L + +++Y+L+GQQG +AC T
Sbjct: 733 KVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPST 792
Query: 501 LSAQESQECSRKPSNESLQVFTSKTHEVRNTHV-IDXXXXXXXXTFVFLMDKEGRPFPLV 559
+ +K V + R+ H T+VF M K+G P PL+
Sbjct: 793 ------NQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKM-KDGVPVPLI 845
Query: 560 VAXXXXXISVGIFRDDGSQHGKPHTNSTPESGYMYGQPDKTSEYVVLGTGAGGGWVARSG 619
+A + G D + H + N++ G + G G GGGW +
Sbjct: 846 IAAGGGGRAYGAKTD--TFHPERLENNSSVLG-LNGNSG--------AAGGGGGWNDNTS 894
Query: 620 PITPGSERVRGA 631
+ G GA
Sbjct: 895 LLWAGKSLQEGA 906
Score = 54.8 bits (126), Expect = 2e-06
Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 12/168 (7%)
Query: 6 VKSPPFRGLWEFCKFEALLHQRMMQNAS-IRLISESTISEVQWILQEVAGNNAENWYPMR 64
+ SP R E C +H+ + + I + + + +L G + W ++
Sbjct: 339 ILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAAREILLMPTPGKHG--WTVLQ 396
Query: 65 FMIGKVQQEVRIIIEITRPNYVSLAQPLPHIAIDNIRMIDCVPEPPVYNGECNAGQLKCK 124
IG+ R+ +E SL+ A+D + +C G A Q
Sbjct: 397 GRIGRPDNPFRVALEYISSGNRSLS------AVDFFALKNC--SEGTSPGSKMALQSSFT 448
Query: 125 IMNRESCIKLHQVCDLVKDCDDGSDEQKNCDKMPYGSYCNFEQDSCGF 172
N + ++L Q CD +DC G DE + C K+P G YCNFE CG+
Sbjct: 449 CWNG-TVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGW 495
>X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein.
Length = 803
Score = 328 bits (807), Expect = 5e-89
Identities = 161/304 (52%), Positives = 214/304 (70%), Gaps = 9/304 (2%)
Query: 796 QKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLP-QGIDVR-GLP 853
QKK + Q + R+ E++L +LR + A+ A NP+Y P Q + G+
Sbjct: 390 QKKWQGLQ-EMRLPSPELELSKLRTS------AIRTAPNPYYCQVGLGPAQSWPLPPGVT 442
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+VS ++ L++ALG GAFGEVY+GL D++ + VA+KTLPEL + Q E DFLMEA
Sbjct: 443 EVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEAL 502
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KF H NIV +G+ PR I+LEL++GGD+K+FLR SRP + S L M+DLL
Sbjct: 503 IISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQL 562
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ +GC YLE FIHRDIAARNCLL+ GP RV KI DFGMARDIYRA YY++G +A
Sbjct: 563 AQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRA 622
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+LP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY G N+EV++ V GGGR++
Sbjct: 623 LLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMD 682
Query: 1094 KPYG 1097
P G
Sbjct: 683 PPRG 686
Score = 79.8 bits (188), Expect = 5e-14
Identities = 42/99 (42%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Query: 400 FTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVWEVPEEGLYTIIA-TXXXX 458
F+ CGASGR+GP QT CD AY T V V V GVQ+W VP G Y I A
Sbjct: 70 FSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGG 129
Query: 459 XXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINAC 497
HG A+ L E +Y+L+GQQG +AC
Sbjct: 130 KGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDAC 168
>D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase
protein.
Length = 864
Score = 328 bits (807), Expect = 5e-89
Identities = 161/304 (52%), Positives = 214/304 (70%), Gaps = 9/304 (2%)
Query: 796 QKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLP-QGIDVR-GLP 853
QKK + Q + R+ E++L +LR + A+ A NP+Y P Q + G+
Sbjct: 451 QKKWQGLQ-EMRLPSPELELSKLRTS------AIRTAPNPYYCQVGLGPAQSWPLPPGVT 503
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+VS ++ L++ALG GAFGEVY+GL D++ + VA+KTLPEL + Q E DFLMEA
Sbjct: 504 EVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEAL 563
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KF H NIV +G+ PR I+LEL++GGD+K+FLR SRP + S L M+DLL
Sbjct: 564 IISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQL 623
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ +GC YLE FIHRDIAARNCLL+ GP RV KI DFGMARDIYRA YY++G +A
Sbjct: 624 AQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRA 683
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+LP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY G N+EV++ V GGGR++
Sbjct: 684 LLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMD 743
Query: 1094 KPYG 1097
P G
Sbjct: 744 PPRG 747
Score = 79.8 bits (188), Expect = 5e-14
Identities = 42/99 (42%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Query: 400 FTPCGASGRYGPNQTMCDAAYNNTPVDVNVLHTHPYTGVQVWEVPEEGLYTIIA-TXXXX 458
F+ CGASGR+GP QT CD AY T V V V GVQ+W VP G Y I A
Sbjct: 70 FSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGG 129
Query: 459 XXXXXXXXXXHGAQARALLELHRSELVYMLIGQQGINAC 497
HG A+ L E +Y+L+GQQG +AC
Sbjct: 130 KGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDAC 168
>X52213-1|CAA36460.1| 464|Homo sapiens ltk protein.
Length = 464
Score = 326 bits (801), Expect = 3e-88
Identities = 162/304 (53%), Positives = 214/304 (70%), Gaps = 10/304 (3%)
Query: 796 QKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLP-QGIDVR-GLP 853
QKK + Q + R+ E++L +LR + A+ A NP+Y P Q + G+
Sbjct: 52 QKKWQGLQ-EMRLPSPELELSKLRTS------AIRTAPNPYYCQVGLGPAQSWPLPPGVT 104
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+VS ++ L++ALG GAFGEVY+GL D++ + VA+KTLPEL + Q E DFLMEA
Sbjct: 105 EVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEAL 164
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
I++KF H NIV +G+ PR I+LEL++GGD+K+FLR SRP + S L M+DLL
Sbjct: 165 IISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQL 224
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ D+ +GC YLE FIHRDIAARNCLL RGP RV KI DFGMARDIYRA YY++G +A
Sbjct: 225 AQDIAQGCHYLEENHFIHRDIAARNCLL-MRGPSRVAKIGDFGMARDIYRASYYRRGDRA 283
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
+LP+KWMPPEA+++G+FT+KTD WSFGVLLWE+FSLG MPY G N+EV++ V GGGR++
Sbjct: 284 LLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMD 343
Query: 1094 KPYG 1097
P G
Sbjct: 344 PPRG 347
>Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 269 bits (660), Expect = 3e-71
Identities = 136/307 (44%), Positives = 196/307 (63%), Gaps = 9/307 (2%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R + ++ A++ ++ ++ +L LR G + +A N Y + LP ++
Sbjct: 1877 HRRLKNQKSAKEGVTVLINEDKELAELRGLAAG----VGLA-NACYAIHT-LPTQEEIEN 1930
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLM 910
LP RE L L LG GAFGEVY+G + E+ VAVKTL + ST Q + +FL
Sbjct: 1931 LPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK 1990
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KFNH NI+ +GVC P++I+LEL+ GGDL +LR++R LT+ DL
Sbjct: 1991 EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDL 2050
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRG--PGRVVKIADFGMARDIYRADYYK 1028
+ VD+ KGC YLE FIHRD+AARNCL++ + R+VKI DFG+ARDIY+ DYY+
Sbjct: 2051 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYR 2110
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DG+FTT++DVWSFG+L+WE+ +LG PY +N +V+ V
Sbjct: 2111 KRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQT 2170
Query: 1089 GGRLEKP 1095
GGRLE P
Sbjct: 2171 GGRLEPP 2177
>Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 269 bits (660), Expect = 3e-71
Identities = 136/307 (44%), Positives = 196/307 (63%), Gaps = 9/307 (2%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R + ++ A++ ++ ++ +L LR G + +A N Y + LP ++
Sbjct: 1883 HRRLKNQKSAKEGVTVLINEDKELAELRGLAAG----VGLA-NACYAIHT-LPTQEEIEN 1936
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLM 910
LP RE L L LG GAFGEVY+G + E+ VAVKTL + ST Q + +FL
Sbjct: 1937 LPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK 1996
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KFNH NI+ +GVC P++I+LEL+ GGDL +LR++R LT+ DL
Sbjct: 1997 EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDL 2056
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRG--PGRVVKIADFGMARDIYRADYYK 1028
+ VD+ KGC YLE FIHRD+AARNCL++ + R+VKI DFG+ARDIY+ DYY+
Sbjct: 2057 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYR 2116
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DG+FTT++DVWSFG+L+WE+ +LG PY +N +V+ V
Sbjct: 2117 KRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQT 2176
Query: 1089 GGRLEKP 1095
GGRLE P
Sbjct: 2177 GGRLEPP 2183
>M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein.
Length = 2347
Score = 269 bits (660), Expect = 3e-71
Identities = 136/307 (44%), Positives = 196/307 (63%), Gaps = 9/307 (2%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R + ++ A++ ++ ++ +L LR G + +A N Y + LP ++
Sbjct: 1883 HRRLKNQKSAKEGVTVLINEDKELAELRGLAAG----VGLA-NACYAIHT-LPTQEEIEN 1936
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLM 910
LP RE L L LG GAFGEVY+G + E+ VAVKTL + ST Q + +FL
Sbjct: 1937 LPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK 1996
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KFNH NI+ +GVC P++I+LEL+ GGDL +LR++R LT+ DL
Sbjct: 1997 EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDL 2056
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRG--PGRVVKIADFGMARDIYRADYYK 1028
+ VD+ KGC YLE FIHRD+AARNCL++ + R+VKI DFG+ARDIY+ DYY+
Sbjct: 2057 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYR 2116
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DG+FTT++DVWSFG+L+WE+ +LG PY +N +V+ V
Sbjct: 2117 KRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQT 2176
Query: 1089 GGRLEKP 1095
GGRLE P
Sbjct: 2177 GGRLEPP 2183
>M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3
(rearranged ros1) proto-oncogene mRNA encoding a
transmembrane protein kinase, 3' end. ).
Length = 494
Score = 269 bits (660), Expect = 3e-71
Identities = 136/307 (44%), Positives = 196/307 (63%), Gaps = 9/307 (2%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R + ++ A++ ++ ++ +L LR G + +A N Y + LP ++
Sbjct: 30 HRRLKNQKSAKEGVTVLINEDKELAELRGLAAG----VGLA-NACYAIHT-LPTQEEIEN 83
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLM 910
LP RE L L LG GAFGEVY+G + E+ VAVKTL + ST Q + +FL
Sbjct: 84 LPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK 143
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KFNH NI+ +GVC P++I+LEL+ GGDL +LR++R LT+ DL
Sbjct: 144 EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDL 203
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRG--PGRVVKIADFGMARDIYRADYYK 1028
+ VD+ KGC YLE FIHRD+AARNCL++ + R+VKI DFG+ARDIY+ DYY+
Sbjct: 204 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYR 263
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DG+FTT++DVWSFG+L+WE+ +LG PY +N +V+ V
Sbjct: 264 KRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQT 323
Query: 1089 GGRLEKP 1095
GGRLE P
Sbjct: 324 GGRLEPP 330
>M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein.
Length = 471
Score = 269 bits (660), Expect = 3e-71
Identities = 136/307 (44%), Positives = 196/307 (63%), Gaps = 9/307 (2%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R + ++ A++ ++ ++ +L LR G + +A N Y + LP ++
Sbjct: 94 HRRLKNQKSAKEGVTVLINEDKELAELRGLAAG----VGLA-NACYAIHT-LPTQEEIEN 147
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLM 910
LP RE L L LG GAFGEVY+G + E+ VAVKTL + ST Q + +FL
Sbjct: 148 LPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK 207
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KFNH NI+ +GVC P++I+LEL+ GGDL +LR++R LT+ DL
Sbjct: 208 EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDL 267
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRG--PGRVVKIADFGMARDIYRADYYK 1028
+ VD+ KGC YLE FIHRD+AARNCL++ + R+VKI DFG+ARDIY+ DYY+
Sbjct: 268 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYR 327
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DG+FTT++DVWSFG+L+WE+ +LG PY +N +V+ V
Sbjct: 328 KRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQT 387
Query: 1089 GGRLEKP 1095
GGRLE P
Sbjct: 388 GGRLEPP 394
>AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 269 bits (660), Expect = 3e-71
Identities = 136/307 (44%), Positives = 196/307 (63%), Gaps = 9/307 (2%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R + ++ A++ ++ ++ +L LR G + +A N Y + LP ++
Sbjct: 1883 HRRLKNQKSAKEGVTVLINEDKELAELRGLAAG----VGLA-NACYAIHT-LPTQEEIEN 1936
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLM 910
LP RE L L LG GAFGEVY+G + E+ VAVKTL + ST Q + +FL
Sbjct: 1937 LPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK 1996
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KFNH NI+ +GVC P++I+LEL+ GGDL +LR++R LT+ DL
Sbjct: 1997 EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDL 2056
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRG--PGRVVKIADFGMARDIYRADYYK 1028
+ VD+ KGC YLE FIHRD+AARNCL++ + R+VKI DFG+ARDIY+ DYY+
Sbjct: 2057 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYR 2116
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DG+FTT++DVWSFG+L+WE+ +LG PY +N +V+ V
Sbjct: 2117 KRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQT 2176
Query: 1089 GGRLEKP 1095
GGRLE P
Sbjct: 2177 GGRLEPP 2183
>AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 269 bits (660), Expect = 3e-71
Identities = 136/307 (44%), Positives = 196/307 (63%), Gaps = 9/307 (2%)
Query: 792 YNRYQKKREARQAQKRIMEQEVQLHRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRG 851
+ R + ++ A++ ++ ++ +L LR G + +A N Y + LP ++
Sbjct: 1877 HRRLKNQKSAKEGVTVLINEDKELAELRGLAAG----VGLA-NACYAIHT-LPTQEEIEN 1930
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRH-RSADAAEMPVAVKTLPELSTGQAESDFLM 910
LP RE L L LG GAFGEVY+G + E+ VAVKTL + ST Q + +FL
Sbjct: 1931 LPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK 1990
Query: 911 EAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL 970
EA +M+KFNH NI+ +GVC P++I+LEL+ GGDL +LR++R LT+ DL
Sbjct: 1991 EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDL 2050
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRG--PGRVVKIADFGMARDIYRADYYK 1028
+ VD+ KGC YLE FIHRD+AARNCL++ + R+VKI DFG+ARDIY+ DYY+
Sbjct: 2051 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYR 2110
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
K G+ +LP++WM PE+ +DG+FTT++DVWSFG+L+WE+ +LG PY +N +V+ V
Sbjct: 2111 KRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQT 2170
Query: 1089 GGRLEKP 1095
GGRLE P
Sbjct: 2171 GGRLEPP 2177
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 243 bits (594), Expect = 3e-63
Identities = 123/287 (42%), Positives = 177/287 (61%), Gaps = 7/287 (2%)
Query: 813 VQLHRLRNAPGGNDNALAMAFNPHYGSES-FLPQGIDVRGLPQVSRESLKLVKALGQGAF 871
+ L + P G L + NP Y S S P + V +VSRE + L++ LGQG+F
Sbjct: 963 IYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSF 1022
Query: 872 GEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCF 931
G VY+G R AE VAVKT+ E ++ + +FL EA++M F ++V L+GV
Sbjct: 1023 GMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS 1082
Query: 932 DRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKR 988
P +V+EL+A GDLK++LR RP+ E T+++++ + ++ G YL K+
Sbjct: 1083 KGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKK 1142
Query: 989 FIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDG 1048
F+HRD+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DG
Sbjct: 1143 FVHRDLAARNCMVAH---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDG 1199
Query: 1049 VFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
VFTT +D+WSFGV+LWE+ SL PY G +N +V++ V GG L++P
Sbjct: 1200 VFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQP 1246
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 243 bits (594), Expect = 3e-63
Identities = 123/287 (42%), Positives = 177/287 (61%), Gaps = 7/287 (2%)
Query: 813 VQLHRLRNAPGGNDNALAMAFNPHYGSES-FLPQGIDVRGLPQVSRESLKLVKALGQGAF 871
+ L + P G L + NP Y S S P + V +VSRE + L++ LGQG+F
Sbjct: 975 IYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSF 1034
Query: 872 GEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCF 931
G VY+G R AE VAVKT+ E ++ + +FL EA++M F ++V L+GV
Sbjct: 1035 GMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS 1094
Query: 932 DRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKR 988
P +V+EL+A GDLK++LR RP+ E T+++++ + ++ G YL K+
Sbjct: 1095 KGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKK 1154
Query: 989 FIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDG 1048
F+HRD+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DG
Sbjct: 1155 FVHRDLAARNCMVAH---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDG 1211
Query: 1049 VFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
VFTT +D+WSFGV+LWE+ SL PY G +N +V++ V GG L++P
Sbjct: 1212 VFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQP 1258
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 243 bits (594), Expect = 3e-63
Identities = 123/287 (42%), Positives = 177/287 (61%), Gaps = 7/287 (2%)
Query: 813 VQLHRLRNAPGGNDNALAMAFNPHYGSES-FLPQGIDVRGLPQVSRESLKLVKALGQGAF 871
+ L + P G L + NP Y S S P + V +VSRE + L++ LGQG+F
Sbjct: 975 IYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSF 1034
Query: 872 GEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCF 931
G VY+G R AE VAVKT+ E ++ + +FL EA++M F ++V L+GV
Sbjct: 1035 GMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS 1094
Query: 932 DRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKR 988
P +V+EL+A GDLK++LR RP+ E T+++++ + ++ G YL K+
Sbjct: 1095 KGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKK 1154
Query: 989 FIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDG 1048
F+HRD+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DG
Sbjct: 1155 FVHRDLAARNCMVAH---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDG 1211
Query: 1049 VFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
VFTT +D+WSFGV+LWE+ SL PY G +N +V++ V GG L++P
Sbjct: 1212 VFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQP 1258
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 243 bits (594), Expect = 3e-63
Identities = 123/287 (42%), Positives = 177/287 (61%), Gaps = 7/287 (2%)
Query: 813 VQLHRLRNAPGGNDNALAMAFNPHYGSES-FLPQGIDVRGLPQVSRESLKLVKALGQGAF 871
+ L + P G L + NP Y S S P + V +VSRE + L++ LGQG+F
Sbjct: 963 IYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSF 1022
Query: 872 GEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCF 931
G VY+G R AE VAVKT+ E ++ + +FL EA++M F ++V L+GV
Sbjct: 1023 GMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS 1082
Query: 932 DRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKR 988
P +V+EL+A GDLK++LR RP+ E T+++++ + ++ G YL K+
Sbjct: 1083 KGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKK 1142
Query: 989 FIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDG 1048
F+HRD+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DG
Sbjct: 1143 FVHRDLAARNCMVAH---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDG 1199
Query: 1049 VFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
VFTT +D+WSFGV+LWE+ SL PY G +N +V++ V GG L++P
Sbjct: 1200 VFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQP 1246
>AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor variant
protein.
Length = 833
Score = 243 bits (594), Expect = 3e-63
Identities = 123/287 (42%), Positives = 177/287 (61%), Gaps = 7/287 (2%)
Query: 813 VQLHRLRNAPGGNDNALAMAFNPHYGSES-FLPQGIDVRGLPQVSRESLKLVKALGQGAF 871
+ L + P G L + NP Y S S P + V +VSRE + L++ LGQG+F
Sbjct: 426 IYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSF 485
Query: 872 GEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCF 931
G VY+G R AE VAVKT+ E ++ + +FL EA++M F ++V L+GV
Sbjct: 486 GMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS 545
Query: 932 DRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKR 988
P +V+EL+A GDLK++LR RP+ E T+++++ + ++ G YL K+
Sbjct: 546 KGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKK 605
Query: 989 FIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDG 1048
F+HRD+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DG
Sbjct: 606 FVHRDLAARNCMVAH---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDG 662
Query: 1049 VFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
VFTT +D+WSFGV+LWE+ SL PY G +N +V++ V GG L++P
Sbjct: 663 VFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQP 709
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 237 bits (581), Expect = 1e-61
Identities = 117/283 (41%), Positives = 173/283 (61%), Gaps = 10/283 (3%)
Query: 816 HRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY 875
HR RN + L + NP Y F + V +V+RE + + + LGQG+FG VY
Sbjct: 959 HRKRNNSRLGNGVLYASVNPEY----FSAADVYVPDEWEVAREKITMSRELGQGSFGMVY 1014
Query: 876 QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHP 935
+G+ + D E VA+KT+ E ++ + +FL EA++M +FN ++V L+GV P
Sbjct: 1015 EGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQP 1074
Query: 936 RFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKRFIHR 992
+++EL+ GDLK++LR RP+ E L ++ ++ + ++ G YL +F+HR
Sbjct: 1075 TLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHR 1134
Query: 993 DIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTT 1052
D+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DGVFTT
Sbjct: 1135 DLAARNCMVAE---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTT 1191
Query: 1053 KTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+DVWSFGV+LWE+ +L PY G +N +V+ V GG L+KP
Sbjct: 1192 YSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKP 1234
>BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 237 bits (581), Expect = 1e-61
Identities = 117/283 (41%), Positives = 173/283 (61%), Gaps = 10/283 (3%)
Query: 816 HRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY 875
HR RN + L + NP Y F + V +V+RE + + + LGQG+FG VY
Sbjct: 959 HRKRNNSRLGNGVLYASVNPEY----FSAADVYVPDEWEVAREKITMSRELGQGSFGMVY 1014
Query: 876 QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHP 935
+G+ + D E VA+KT+ E ++ + +FL EA++M +FN ++V L+GV P
Sbjct: 1015 EGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQP 1074
Query: 936 RFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKRFIHR 992
+++EL+ GDLK++LR RP+ E L ++ ++ + ++ G YL +F+HR
Sbjct: 1075 TLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHR 1134
Query: 993 DIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTT 1052
D+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DGVFTT
Sbjct: 1135 DLAARNCMVAE---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTT 1191
Query: 1053 KTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+DVWSFGV+LWE+ +L PY G +N +V+ V GG L+KP
Sbjct: 1192 YSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKP 1234
>BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 237 bits (581), Expect = 1e-61
Identities = 117/283 (41%), Positives = 173/283 (61%), Gaps = 10/283 (3%)
Query: 816 HRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY 875
HR RN + L + NP Y F + V +V+RE + + + LGQG+FG VY
Sbjct: 959 HRKRNNSRLGNGVLYASVNPEY----FSAADVYVPDEWEVAREKITMSRELGQGSFGMVY 1014
Query: 876 QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHP 935
+G+ + D E VA+KT+ E ++ + +FL EA++M +FN ++V L+GV P
Sbjct: 1015 EGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQP 1074
Query: 936 RFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKRFIHR 992
+++EL+ GDLK++LR RP+ E L ++ ++ + ++ G YL +F+HR
Sbjct: 1075 TLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHR 1134
Query: 993 DIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTT 1052
D+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DGVFTT
Sbjct: 1135 DLAARNCMVAE---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTT 1191
Query: 1053 KTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+DVWSFGV+LWE+ +L PY G +N +V+ V GG L+KP
Sbjct: 1192 YSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKP 1234
>AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 237 bits (581), Expect = 1e-61
Identities = 117/283 (41%), Positives = 173/283 (61%), Gaps = 10/283 (3%)
Query: 816 HRLRNAPGGNDNALAMAFNPHYGSESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY 875
HR RN + L + NP Y F + V +V+RE + + + LGQG+FG VY
Sbjct: 959 HRKRNNSRLGNGVLYASVNPEY----FSAADVYVPDEWEVAREKITMSRELGQGSFGMVY 1014
Query: 876 QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHP 935
+G+ + D E VA+KT+ E ++ + +FL EA++M +FN ++V L+GV P
Sbjct: 1015 EGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQP 1074
Query: 936 RFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDLLLCSVDVCKGCRYLETKRFIHR 992
+++EL+ GDLK++LR RP+ E L ++ ++ + ++ G YL +F+HR
Sbjct: 1075 TLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHR 1134
Query: 993 DIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTT 1052
D+AARNC++ VKI DFGM RDIY DYY+KGGK +LP++WM PE+ DGVFTT
Sbjct: 1135 DLAARNCMVAE---DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTT 1191
Query: 1053 KTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
+DVWSFGV+LWE+ +L PY G +N +V+ V GG L+KP
Sbjct: 1192 YSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKP 1234
>J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related
receptor protein.
Length = 1268
Score = 232 bits (567), Expect = 6e-60
Identities = 107/247 (43%), Positives = 160/247 (64%), Gaps = 6/247 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V RE + +++ LGQG+FG VY+GL R A PVA+KT+ EL++ + +FL EA+
Sbjct: 944 EVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEAS 1003
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDL 970
+M F ++V L+GV P +++EL+ GDLK+ LR RP+ E L + ++
Sbjct: 1004 VMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEM 1063
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
+ + ++ G YL +F+HRD+AARNC+++ VKI DFGM RD+Y DYY+KG
Sbjct: 1064 IQMAGEIADGMAYLAANKFVHRDLAARNCMVSQ---DFTVKIGDFGMTRDVYETDYYRKG 1120
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
GK +LP++WM PE+ DG+FTT +DVWSFGV+LWE+ +L PY G +N +V++ V GG
Sbjct: 1121 GKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGG 1180
Query: 1091 RLEKPYG 1097
LE+ G
Sbjct: 1181 VLEELEG 1187
>AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-related
receptor protein.
Length = 1297
Score = 232 bits (567), Expect = 6e-60
Identities = 107/247 (43%), Positives = 160/247 (64%), Gaps = 6/247 (2%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+V RE + +++ LGQG+FG VY+GL R A PVA+KT+ EL++ + +FL EA+
Sbjct: 973 EVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEAS 1032
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL---TMKDL 970
+M F ++V L+GV P +++EL+ GDLK+ LR RP+ E L + ++
Sbjct: 1033 VMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEM 1092
Query: 971 LLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKG 1030
+ + ++ G YL +F+HRD+AARNC+++ VKI DFGM RD+Y DYY+KG
Sbjct: 1093 IQMAGEIADGMAYLAANKFVHRDLAARNCMVSQ---DFTVKIGDFGMTRDVYETDYYRKG 1149
Query: 1031 GKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGG 1090
GK +LP++WM PE+ DG+FTT +DVWSFGV+LWE+ +L PY G +N +V++ V GG
Sbjct: 1150 GKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGG 1209
Query: 1091 RLEKPYG 1097
LE+ G
Sbjct: 1210 VLEELEG 1216
>M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein.
Length = 731
Score = 203 bits (495), Expect = 3e-51
Identities = 111/255 (43%), Positives = 152/255 (59%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPV--AVKTLPELSTGQAESDFLME 911
++SR L L K LG+G FG+V D A PV AVK L + +T + SD + E
Sbjct: 391 ELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSE 450
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPE 960
+M H NI++L+G C P ++++E A G+L+ FLR RP KP
Sbjct: 451 MEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP 510
Query: 961 RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD
Sbjct: 511 EEQ-LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTE---DNVMKIADFGLARD 566
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
++ DYYKK LP+KWM PEA D V+T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 567 VHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVE 626
Query: 1081 EVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 627 ELFKLLKEGHRMDKP 641
>M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor
receptor protein.
Length = 806
Score = 203 bits (495), Expect = 3e-51
Identities = 111/255 (43%), Positives = 152/255 (59%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPV--AVKTLPELSTGQAESDFLME 911
++SR L L K LG+G FG+V D A PV AVK L + +T + SD + E
Sbjct: 466 ELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSE 525
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPE 960
+M H NI++L+G C P ++++E A G+L+ FLR RP KP
Sbjct: 526 MEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP 585
Query: 961 RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD
Sbjct: 586 EEQ-LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTE---DNVMKIADFGLARD 641
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
++ DYYKK LP+KWM PEA D V+T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 642 VHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVE 701
Query: 1081 EVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 702 ELFKLLKEGHRMDKP 716
>BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein.
Length = 480
Score = 203 bits (495), Expect = 3e-51
Identities = 111/255 (43%), Positives = 152/255 (59%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPV--AVKTLPELSTGQAESDFLME 911
++SR L L K LG+G FG+V D A PV AVK L + +T + SD + E
Sbjct: 140 ELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSE 199
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPE 960
+M H NI++L+G C P ++++E A G+L+ FLR RP KP
Sbjct: 200 MEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP 259
Query: 961 RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD
Sbjct: 260 EEQ-LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTE---DNVMKIADFGLARD 315
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
++ DYYKK LP+KWM PEA D V+T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 316 VHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVE 375
Query: 1081 EVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 376 ELFKLLKEGHRMDKP 390
>BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein.
Length = 480
Score = 203 bits (495), Expect = 3e-51
Identities = 111/255 (43%), Positives = 152/255 (59%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPV--AVKTLPELSTGQAESDFLME 911
++SR L L K LG+G FG+V D A PV AVK L + +T + SD + E
Sbjct: 140 ELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSE 199
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPE 960
+M H NI++L+G C P ++++E A G+L+ FLR RP KP
Sbjct: 200 MEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP 259
Query: 961 RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD
Sbjct: 260 EEQ-LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTE---DNVMKIADFGLARD 315
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
++ DYYKK LP+KWM PEA D V+T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 316 VHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVE 375
Query: 1081 EVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 376 ELFKLLKEGHRMDKP 390
>AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth factor
receptor 3 (achondroplasia, thanatophoric dwarfism)
protein.
Length = 806
Score = 203 bits (495), Expect = 3e-51
Identities = 111/255 (43%), Positives = 152/255 (59%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPV--AVKTLPELSTGQAESDFLME 911
++SR L L K LG+G FG+V D A PV AVK L + +T + SD + E
Sbjct: 466 ELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSE 525
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPE 960
+M H NI++L+G C P ++++E A G+L+ FLR RP KP
Sbjct: 526 MEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP 585
Query: 961 RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD
Sbjct: 586 EEQ-LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTE---DNVMKIADFGLARD 641
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
++ DYYKK LP+KWM PEA D V+T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 642 VHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVE 701
Query: 1081 EVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 702 ELFKLLKEGHRMDKP 716
>AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 769
Score = 203 bits (495), Expect = 3e-51
Identities = 111/255 (43%), Positives = 152/255 (59%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPV--AVKTLPELSTGQAESDFLME 911
++SR L L K LG+G FG+V D A PV AVK L + +T + SD + E
Sbjct: 429 ELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSE 488
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPE 960
+M H NI++L+G C P ++++E A G+L+ FLR RP KP
Sbjct: 489 MEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP 548
Query: 961 RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD
Sbjct: 549 EEQ-LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTE---DNVMKIADFGLARD 604
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
++ DYYKK LP+KWM PEA D V+T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 605 VHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVE 664
Query: 1081 EVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 665 ELFKLLKEGHRMDKP 679
>AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 771
Score = 203 bits (495), Expect = 3e-51
Identities = 111/255 (43%), Positives = 152/255 (59%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPV--AVKTLPELSTGQAESDFLME 911
++SR L L K LG+G FG+V D A PV AVK L + +T + SD + E
Sbjct: 431 ELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSE 490
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPE 960
+M H NI++L+G C P ++++E A G+L+ FLR RP KP
Sbjct: 491 MEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP 550
Query: 961 RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD
Sbjct: 551 EEQ-LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTE---DNVMKIADFGLARD 606
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
++ DYYKK LP+KWM PEA D V+T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 607 VHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVE 666
Query: 1081 EVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 667 ELFKLLKEGHRMDKP 681
>AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 694
Score = 203 bits (495), Expect = 3e-51
Identities = 111/255 (43%), Positives = 152/255 (59%), Gaps = 17/255 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPV--AVKTLPELSTGQAESDFLME 911
++SR L L K LG+G FG+V D A PV AVK L + +T + SD + E
Sbjct: 354 ELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSE 413
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP----------KPE 960
+M H NI++L+G C P ++++E A G+L+ FLR RP KP
Sbjct: 414 MEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP 473
Query: 961 RASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARD 1020
LT KDL+ C+ V +G YL +++ IHRD+AARN L+T V+KIADFG+ARD
Sbjct: 474 EEQ-LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTE---DNVMKIADFGLARD 529
Query: 1021 IYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANR 1080
++ DYYKK LP+KWM PEA D V+T ++DVWSFGVLLWE+F+LG PY G
Sbjct: 530 VHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVE 589
Query: 1081 EVMELVSGGGRLEKP 1095
E+ +L+ G R++KP
Sbjct: 590 ELFKLLKEGHRMDKP 604
>AF125808-1|AAF19762.1| 318|Homo sapiens ETS related
protein-neurotrophic receptor tyrosine kinase fusion
protein protein.
Length = 318
Score = 200 bits (487), Expect = 3e-50
Identities = 107/265 (40%), Positives = 153/265 (57%), Gaps = 14/265 (5%)
Query: 840 ESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPEL 899
E +P G + + + R + L + LG+GAFG+V+ + S +M VAVK L +
Sbjct: 12 EHAMPIG-RIADVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD- 69
Query: 900 STGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-- 957
T A DF EA ++ H +IV GVC D P +V E + GDL FLR P
Sbjct: 70 PTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDA 129
Query: 958 ------KPERASA-LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVV 1010
+P +A L + +L + + G YL ++ F+HRD+A RNCL+ G +V
Sbjct: 130 MILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV---GANLLV 186
Query: 1011 KIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLG 1070
KI DFGM+RD+Y DYY+ GG MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G
Sbjct: 187 KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYG 246
Query: 1071 VMPYTGCANREVMELVSGGGRLEKP 1095
P+ +N EV+E ++ G LE+P
Sbjct: 247 KQPWFQLSNTEVIECITQGRVLERP 271
>AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-growth
factor receptor tyrosine kinase fusion proteins protein.
Length = 408
Score = 200 bits (487), Expect = 3e-50
Identities = 107/265 (40%), Positives = 153/265 (57%), Gaps = 14/265 (5%)
Query: 840 ESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPEL 899
E +P G + + + R + L + LG+GAFG+V+ + S +M VAVK L +
Sbjct: 102 EHAMPIG-RIADVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD- 159
Query: 900 STGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-- 957
T A DF EA ++ H +IV GVC D P +V E + GDL FLR P
Sbjct: 160 PTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDA 219
Query: 958 ------KPERASA-LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVV 1010
+P +A L + +L + + G YL ++ F+HRD+A RNCL+ G +V
Sbjct: 220 MILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV---GANLLV 276
Query: 1011 KIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLG 1070
KI DFGM+RD+Y DYY+ GG MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G
Sbjct: 277 KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYG 336
Query: 1071 VMPYTGCANREVMELVSGGGRLEKP 1095
P+ +N EV+E ++ G LE+P
Sbjct: 337 KQPWFQLSNTEVIECITQGRVLERP 361
>X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein
protein.
Length = 591
Score = 199 bits (486), Expect = 4e-50
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 289 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAESHNLLPEQDKMLVAVKALKEASES- 347
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 348 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 407
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 408 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 464
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 465 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 524
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 525 QLSNTEAIDCITQGRELERP 544
>X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein.
Length = 503
Score = 199 bits (486), Expect = 4e-50
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 201 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES- 259
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 260 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 319
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 320 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 376
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 377 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 436
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 437 QLSNTEAIDCITQGRELERP 456
>X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for
trk-2h oncogene. ).
Length = 439
Score = 199 bits (486), Expect = 4e-50
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 137 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES- 195
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 196 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 255
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 256 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 312
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 313 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 372
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 373 QLSNTEAIDCITQGRELERP 392
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 199 bits (486), Expect = 4e-50
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 317 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES- 375
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 376 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 435
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 436 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 492
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 493 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 552
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 553 QLSNTEAIDCITQGRELERP 572
>M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk
proto-oncogene insert of pLM6. ).
Length = 790
Score = 199 bits (486), Expect = 4e-50
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 488 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES- 546
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 547 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 606
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 607 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 663
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 664 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 723
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 724 QLSNTEAIDCITQGRELERP 743
>BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein.
Length = 795
Score = 199 bits (486), Expect = 4e-50
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 493 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES- 551
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 552 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 611
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 612 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 668
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 669 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 728
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 729 QLSNTEAIDCITQGRELERP 748
>AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 1 protein.
Length = 790
Score = 199 bits (486), Expect = 4e-50
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 488 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES- 546
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 547 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 606
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 607 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 663
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 664 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 723
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 724 QLSNTEAIDCITQGRELERP 743
>AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein.
Length = 796
Score = 199 bits (486), Expect = 4e-50
Identities = 106/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 844 PQGIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQ 903
PQ + + R + L LG+GAFG+V+ + + +M VAVK L E S
Sbjct: 494 PQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES- 552
Query: 904 AESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS 963
A DF EA ++ H +IV GVC + P +V E + GDL FLR P + +
Sbjct: 553 ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA 612
Query: 964 A--------LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADF 1015
L + LL + V G YL F+HRD+A RNCL+ G G VVKI DF
Sbjct: 613 GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQGLVVKIGDF 669
Query: 1016 GMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYT 1075
GM+RDIY DYY+ GG+ MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+
Sbjct: 670 GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY 729
Query: 1076 GCANREVMELVSGGGRLEKP 1095
+N E ++ ++ G LE+P
Sbjct: 730 QLSNTEAIDCITQGRELERP 749
>U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein.
Length = 825
Score = 199 bits (485), Expect = 5e-50
Identities = 104/250 (41%), Positives = 147/250 (58%), Gaps = 13/250 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R + L + LG+GAFG+V+ + S +M VAVK L + T A DF EA +
Sbjct: 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD-PTLAARKDFQREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP--------KPERASA-L 965
+ H +IV GVC D P +V E + GDL FLR P +P +A L
Sbjct: 592 LTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPNAMILVDGQPRQAKGEL 651
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+ +L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y D
Sbjct: 652 GLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV---GANLLVKIGDFGMSRDVYSTD 708
Query: 1026 YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMEL 1085
YY+ GG MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G P+ +N EV+E
Sbjct: 709 YYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIEC 768
Query: 1086 VSGGGRLEKP 1095
++ G LE+P
Sbjct: 769 ITQGRVLERP 778
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 198 bits (484), Expect = 7e-50
Identities = 109/241 (45%), Positives = 148/241 (61%), Gaps = 16/241 (6%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+S E + L + LG+G FGEVY+G + +++ VAVKT E + + FL EA I
Sbjct: 558 LSHEDVILGELLGKGNFGEVYKGTLKDKTS------VAVKTCKEDLPQELKIKFLQEAKI 611
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC R P +I++EL++GGD FLR R K E L +K L+ S
Sbjct: 612 LKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLR--RKKDE----LKLKQLVKFS 665
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+D G YLE+K IHRD+AARNCL+ G V+KI+DFGM+R Y G
Sbjct: 666 LDAAAGMLYLESKNCIHRDLAARNCLV---GENNVLKISDFGMSRQ-EDGGVYSSSGLKQ 721
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+PIKW PEA G +++++DVWSFG+LLWE FSLGV PY G N++ E V G R+
Sbjct: 722 IPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSA 781
Query: 1095 P 1095
P
Sbjct: 782 P 782
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 197 bits (480), Expect = 2e-49
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 793 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 851
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 852 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 911
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 912 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 967
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 968 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 1027
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 1028 QPEGCPSKLYRLMQR 1042
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 197 bits (480), Expect = 2e-49
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 793 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 851
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 852 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 911
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 912 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 967
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 968 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 1027
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 1028 QPEGCPSKLYRLMQR 1042
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 197 bits (480), Expect = 2e-49
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 793 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 851
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 852 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 911
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 912 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 967
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 968 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 1027
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 1028 QPEGCPSKLYRLMQR 1042
>AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor
precursor PTK7-4 protein.
Length = 1014
Score = 197 bits (480), Expect = 2e-49
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 737 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 795
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 796 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 855
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 856 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 911
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 912 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 971
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 972 QPEGCPSKLYRLMQR 986
>AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor
precursor PTK7-3 protein.
Length = 940
Score = 197 bits (480), Expect = 2e-49
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 663 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 721
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 722 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 781
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 782 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 837
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 838 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 897
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 898 QPEGCPSKLYRLMQR 912
>AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor
precursor PTK7-2 protein.
Length = 1030
Score = 197 bits (480), Expect = 2e-49
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 753 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 811
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 812 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 871
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 872 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 927
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 928 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 987
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 988 QPEGCPSKLYRLMQR 1002
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 197 bits (480), Expect = 2e-49
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 793 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 851
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 852 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 911
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 912 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 967
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 968 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 1027
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 1028 QPEGCPSKLYRLMQR 1042
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 197 bits (480), Expect = 2e-49
Identities = 102/255 (40%), Positives = 160/255 (62%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 793 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 851
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + GDLK FLR S+ K E+ + L+ K +
Sbjct: 852 KLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALC 911
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 912 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 967
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+P++WM PEA ++G F+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 968 VPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 1027
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 1028 QPEGCPSKLYRLMQR 1042
>U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor
p145TRK-B protein.
Length = 822
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 651
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 652 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 708
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 769 GRVLQRP 775
>S76473-1|AAB33109.1| 822|Homo sapiens trkB protein.
Length = 822
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 651
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 652 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 708
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 769 GRVLQRP 775
>AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 651
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 652 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 708
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 769 GRVLQRP 775
>AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 549 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 607
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 608 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 667
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 668 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 724
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 725 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 784
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 785 GRVLQRP 791
>AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 651
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 652 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 708
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 769 GRVLQRP 775
>AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 549 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 607
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 608 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 667
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 668 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 724
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 725 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 784
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 785 GRVLQRP 791
>AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 651
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 652 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 708
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 769 GRVLQRP 775
>AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 549 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 607
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 608 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 667
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 668 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 724
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 725 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 784
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 785 GRVLQRP 791
>AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor
tyrosine kinase type 2 protein.
Length = 838
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 549 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 607
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 608 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 667
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 668 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 724
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 725 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 784
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 785 GRVLQRP 791
>AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine kinase
receptor type 2 protein.
Length = 822
Score = 196 bits (478), Expect = 4e-49
Identities = 99/247 (40%), Positives = 146/247 (59%), Gaps = 10/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R ++ L + LG+GAFG+V+ + + ++ VAVKTL + S A DF EA +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDN-ARKDFHREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP------KPERASALTMK 968
+ H +IV GVC + P +V E + GDL FLR P + + LT
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQS 651
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
+L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y DYY+
Sbjct: 652 QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GENLLVKIGDFGMSRDVYSTDYYR 708
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
GG MLPI+WMPPE+ + FTT++DVWS GV+LWE+F+ G P+ +N EV+E ++
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 1089 GGRLEKP 1095
G L++P
Sbjct: 769 GRVLQRP 775
>Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein.
Length = 821
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 478 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 535
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 536 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 595
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 596 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 652
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 653 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 712
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 713 FKLLKEGHRMDKPANCTNELYMMMR 737
>X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor
(FGR) receptor protein.
Length = 769
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA for
fibroblast growth factor receptor-BEK. ).
Length = 821
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 478 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 535
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 536 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 595
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 596 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 652
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 653 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 712
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 713 FKLLKEGHRMDKPANCTNELYMMMR 737
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 194 bits (474), Expect = 1e-48
Identities = 105/241 (43%), Positives = 143/241 (59%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ E L L + +G+G FGEV+ G R A VAVK+ E ++ FL EA I
Sbjct: 556 LNHEDLVLGEQIGRGNFGEVFSGRLR-----ADNTLVAVKSCRETLPPDLKAKFLQEARI 610
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC + P +IV+EL+ GGD FLR + L +K LL
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE------GARLRVKTLLQMV 664
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
D G YLE+K IHRD+AARNCL+T + V+KI+DFGM+R+ Y GG
Sbjct: 665 GDAAAGMEYLESKCCIHRDLAARNCLVTEKN---VLKISDFGMSREEADGVYAASGGSRQ 721
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+P+KW PEA G +++++DVWSFG+LLWE FSLG PY +N++ E V GGRL
Sbjct: 722 VPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPC 781
Query: 1095 P 1095
P
Sbjct: 782 P 782
>M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor
receptor protein.
Length = 705
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 362 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 419
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 420 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 479
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 480 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 536
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 537 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 596
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 597 FKLLKEGHRMDKPANCTNELYMMMR 621
>M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor
receptor protein.
Length = 821
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 478 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 535
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 536 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 595
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 596 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 652
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 653 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 712
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 713 FKLLKEGHRMDKPANCTNELYMMMR 737
>M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein.
Length = 822
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth factor
receptor protein protein.
Length = 731
Score = 194 bits (474), Expect = 1e-48
Identities = 111/281 (39%), Positives = 162/281 (57%), Gaps = 19/281 (6%)
Query: 839 SESFLPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTL 896
SE LP+ D+R ++ R+ L L K LG+G FG+V + + + VAVK L
Sbjct: 370 SEYELPE--DLRW--ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKML 425
Query: 897 PELSTGQAESDFLMEAAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRES 955
+T + SD + E +M H NI++L+G C P ++++E + G+L+ +L+
Sbjct: 426 KSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQAR 485
Query: 956 RP-------KPER--ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGP 1006
RP P L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T
Sbjct: 486 RPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE--- 542
Query: 1007 GRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEV 1066
V+KIADFG+ARDI+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+
Sbjct: 543 DNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEI 602
Query: 1067 FSLGVMPYTGCANREVMELVSGGGRLEKPYGEGSEYHKFKR 1107
F+LG PY G E+ +L+ G R++KP +E + R
Sbjct: 603 FTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 643
>M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human
heparin-binding growth factor receptor K-sam mRNA. ).
Length = 682
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 388 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 445
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 446 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 505
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 506 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 562
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 563 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 622
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 623 FKLLKEGHRMDKPANCTNELYMMMR 647
>DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth factor
receptor 2 (bacteria-expressed kinase, keratinocyte gr
protein.
Length = 785
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 476 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 533
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 534 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 593
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 594 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 650
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 651 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 710
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 711 FKLLKEGHRMDKPANCTNELYMMMR 735
>BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein.
Length = 704
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 361 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 418
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 419 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 478
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 479 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 535
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 536 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 595
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 596 FKLLKEGHRMDKPANCTNELYMMMR 620
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes variant
4 protein.
Length = 752
Score = 194 bits (474), Expect = 1e-48
Identities = 105/241 (43%), Positives = 143/241 (59%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ E L L + +G+G FGEV+ G R A VAVK+ E ++ FL EA I
Sbjct: 486 LNHEDLVLGEQIGRGNFGEVFSGRLR-----ADNTLVAVKSCRETLPPDLKAKFLQEARI 540
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC + P +IV+EL+ GGD FLR + L +K LL
Sbjct: 541 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE------GARLRVKTLLQMV 594
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
D G YLE+K IHRD+AARNCL+T + V+KI+DFGM+R+ Y GG
Sbjct: 595 GDAAAGMEYLESKCCIHRDLAARNCLVTEKN---VLKISDFGMSREEADGVYAASGGSRQ 651
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+P+KW PEA G +++++DVWSFG+LLWE FSLG PY +N++ E V GGRL
Sbjct: 652 VPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPC 711
Query: 1095 P 1095
P
Sbjct: 712 P 712
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes variant
3 protein.
Length = 764
Score = 194 bits (474), Expect = 1e-48
Identities = 105/241 (43%), Positives = 143/241 (59%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ E L L + +G+G FGEV+ G R A VAVK+ E ++ FL EA I
Sbjct: 498 LNHEDLVLGEQIGRGNFGEVFSGRLR-----ADNTLVAVKSCRETLPPDLKAKFLQEARI 552
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC + P +IV+EL+ GGD FLR + L +K LL
Sbjct: 553 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE------GARLRVKTLLQMV 606
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
D G YLE+K IHRD+AARNCL+T + V+KI+DFGM+R+ Y GG
Sbjct: 607 GDAAAGMEYLESKCCIHRDLAARNCLVTEKN---VLKISDFGMSREEADGVYAASGGSRQ 663
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+P+KW PEA G +++++DVWSFG+LLWE FSLG PY +N++ E V GGRL
Sbjct: 664 VPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPC 723
Query: 1095 P 1095
P
Sbjct: 724 P 724
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes variant
1 protein.
Length = 694
Score = 194 bits (474), Expect = 1e-48
Identities = 105/241 (43%), Positives = 143/241 (59%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ E L L + +G+G FGEV+ G R A VAVK+ E ++ FL EA I
Sbjct: 428 LNHEDLVLGEQIGRGNFGEVFSGRLR-----ADNTLVAVKSCRETLPPDLKAKFLQEARI 482
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC + P +IV+EL+ GGD FLR + L +K LL
Sbjct: 483 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE------GARLRVKTLLQMV 536
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
D G YLE+K IHRD+AARNCL+T + V+KI+DFGM+R+ Y GG
Sbjct: 537 GDAAAGMEYLESKCCIHRDLAARNCLVTEKN---VLKISDFGMSREEADGVYAASGGSRQ 593
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+P+KW PEA G +++++DVWSFG+LLWE FSLG PY +N++ E V GGRL
Sbjct: 594 VPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPC 653
Query: 1095 P 1095
P
Sbjct: 654 P 654
>AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC3 protein.
Length = 766
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 476 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 533
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 534 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 593
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 594 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 650
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 651 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 710
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 711 FKLLKEGHRMDKPANCTNELYMMMR 735
>AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC2 protein.
Length = 785
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 476 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 533
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 534 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 593
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 594 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 650
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 651 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 710
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 711 FKLLKEGHRMDKPANCTNELYMMMR 735
>AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth factor
receptor 2 isoform BEK protein.
Length = 819
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 476 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 533
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 534 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 593
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 594 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 650
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 651 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 710
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 711 FKLLKEGHRMDKPANCTNELYMMMR 735
>AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth factor
receptor 2 isoform KGFR protein.
Length = 820
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 477 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 534
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 535 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 594
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 595 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 651
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 652 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 711
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 712 FKLLKEGHRMDKPANCTNELYMMMR 736
>AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth factor
receptor 2 isoform IgIIIc isoform protein.
Length = 554
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 265 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 322
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 323 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 382
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 383 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 439
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 440 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 499
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 500 FKLLKEGHRMDKPANCTNELYMMMR 524
>AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth receptor 2
IgIIIb isoform protein.
Length = 555
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 266 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 323
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 324 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 383
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 384 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 440
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 441 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 500
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 501 FKLLKEGHRMDKPANCTNELYMMMR 525
>AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein.
Length = 709
Score = 194 bits (474), Expect = 1e-48
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 366 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 423
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 424 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 483
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + +G YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 484 EQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 540
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 541 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 600
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 601 FKLLKEGHRMDKPANCTNELYMMMR 625
>Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein.
Length = 622
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 272 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 331
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 332 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 391
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 392 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 448
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 449 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 508
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 509 LFKLLKEGHRMDKPSNCTNELYMMMR 534
>X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor
receptor protein.
Length = 822
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 472 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 531
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 532 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 591
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 592 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 648
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 649 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 708
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 709 LFKLLKEGHRMDKPSNCTNELYMMMR 734
>X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor
Receptor, 2 Ig-Domain Form protein.
Length = 731
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 381 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 440
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 441 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 500
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 501 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 557
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 558 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 617
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 618 LFKLLKEGHRMDKPSNCTNELYMMMR 643
>X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor
Receptor, 3-Ig Domain+2orm protein.
Length = 822
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 472 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 531
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 532 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 591
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 592 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 648
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 649 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 708
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 709 LFKLLKEGHRMDKPSNCTNELYMMMR 734
>X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor
Receptor, 3 Ig-Domain Form protein.
Length = 820
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 470 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 529
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 530 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 589
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 590 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 646
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 647 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 706
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 707 LFKLLKEGHRMDKPSNCTNELYMMMR 732
>X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor
Receptor, 2-Ig Domain+25-1 protein.
Length = 733
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 383 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 442
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 443 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 502
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 503 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 559
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 560 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 619
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 620 LFKLLKEGHRMDKPSNCTNELYMMMR 645
>X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA for
fibroblast growth factor receptor-FLG. ).
Length = 822
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 472 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 531
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 532 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 591
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 592 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 648
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 649 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 708
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 709 LFKLLKEGHRMDKPSNCTNELYMMMR 734
>X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for
fibroblast growth factor (FGF) receptor. ).
Length = 822
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 472 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 531
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 532 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 591
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 592 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 648
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 649 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 708
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 709 LFKLLKEGHRMDKPSNCTNELYMMMR 734
>M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth factor
receptor protein.
Length = 822
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 472 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 531
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 532 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 591
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 592 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 648
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 649 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 708
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 709 LFKLLKEGHRMDKPSNCTNELYMMMR 734
>M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor
receptor protein.
Length = 820
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 470 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 529
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 530 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 589
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 590 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 646
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 647 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 706
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 707 LFKLLKEGHRMDKPSNCTNELYMMMR 732
>M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblast
growth factor (FGF) receptor-1 mRNA, complete cds. ).
Length = 820
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 470 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 529
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 530 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 589
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 590 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 646
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 647 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 706
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 707 LFKLLKEGHRMDKPSNCTNELYMMMR 732
>M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 731
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 381 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 440
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 441 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 500
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 501 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 557
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 558 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 617
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 618 LFKLLKEGHRMDKPSNCTNELYMMMR 643
>M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 733
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 383 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 442
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 443 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 502
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 503 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 559
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 560 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 619
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 620 LFKLLKEGHRMDKPSNCTNELYMMMR 645
>BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 731
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 381 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 440
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 441 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 500
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 501 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 557
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 558 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 617
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 618 LFKLLKEGHRMDKPSNCTNELYMMMR 643
>BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 820
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 470 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 529
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 530 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 589
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 590 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 646
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 647 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 706
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 707 LFKLLKEGHRMDKPSNCTNELYMMMR 732
>BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein.
Length = 820
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 470 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 529
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 530 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 589
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 590 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 646
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 647 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 706
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 707 LFKLLKEGHRMDKPSNCTNELYMMMR 732
>AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 822
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 472 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 531
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 532 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 591
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 592 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 648
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 649 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 708
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 709 LFKLLKEGHRMDKPSNCTNELYMMMR 734
>AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth factor
receptor 1 isoform 1 precursor variant protein.
Length = 814
Score = 194 bits (473), Expect = 1e-48
Identities = 105/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L K LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 464 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 523
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 524 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNP 583
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 584 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 640
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 641 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 700
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 701 LFKLLKEGHRMDKPSNCTNELYMMMR 726
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 194 bits (472), Expect = 2e-48
Identities = 105/241 (43%), Positives = 143/241 (59%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ E L L + +G+G FGEV+ G R A VAVK+ E ++ FL EA I
Sbjct: 556 LNHEDLVLGEQIGRGNFGEVFSGRLR-----ADNTLVAVKSCRETLPPDLKAKFLQEARI 610
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC + P +IV+EL+ GGD FLR + L +K LL
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE------GARLRVKTLLQMV 664
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
D G YLE+K IHRD+AARNCL+T + V+KI+DFGM+R+ Y GG
Sbjct: 665 GDAAAGMEYLESKCCIHRDLAARNCLVTEKN---VLKISDFGMSREEADGVYAASGGLRQ 721
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+P+KW PEA G +++++DVWSFG+LLWE FSLG PY +N++ E V GGRL
Sbjct: 722 VPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPC 781
Query: 1095 P 1095
P
Sbjct: 782 P 782
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 194 bits (472), Expect = 2e-48
Identities = 105/241 (43%), Positives = 143/241 (59%), Gaps = 14/241 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
++ E L L + +G+G FGEV+ G R A VAVK+ E ++ FL EA I
Sbjct: 556 LNHEDLVLGEQIGRGNFGEVFSGRLR-----ADNTLVAVKSCRETLPPDLKAKFLQEARI 610
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
+ +++H NIV LIGVC + P +IV+EL+ GGD FLR + L +K LL
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTE------GARLRVKTLLQMV 664
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
D G YLE+K IHRD+AARNCL+T + V+KI+DFGM+R+ Y GG
Sbjct: 665 GDAAAGMEYLESKCCIHRDLAARNCLVTEKN---VLKISDFGMSREEADGVYAASGGLRQ 721
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
+P+KW PEA G +++++DVWSFG+LLWE FSLG PY +N++ E V GGRL
Sbjct: 722 VPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPC 781
Query: 1095 P 1095
P
Sbjct: 782 P 782
>AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth factor
receptor 1 isoform 2 precursor variant protein.
Length = 820
Score = 192 bits (468), Expect = 6e-48
Identities = 104/266 (39%), Positives = 154/266 (57%), Gaps = 15/266 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVY--QGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
++ R+ L L + LG+G FG+V + + + VAVK L +T + SD + E
Sbjct: 470 ELPRDRLVLGRPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISE 529
Query: 912 AAIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-------KPER-- 961
+M H NI++L+G C P ++++E + G+L+ +L+ RP P
Sbjct: 530 MEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQAWRPPGLEYCYNPSHNP 589
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L+ KDL+ C+ V +G YL +K+ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 590 EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE---DNVMKIADFGLARDI 646
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
+ DYYKK LP+KWM PEA D ++T ++DVWSFGVLLWE+F+LG PY G E
Sbjct: 647 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 706
Query: 1082 VMELVSGGGRLEKPYGEGSEYHKFKR 1107
+ +L+ G R++KP +E + R
Sbjct: 707 LFKLLKEGHRMDKPSNCTNELYMMMR 732
>M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth factor
receptor protein.
Length = 822
Score = 191 bits (466), Expect = 1e-47
Identities = 105/265 (39%), Positives = 155/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + + YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein.
Length = 768
Score = 191 bits (466), Expect = 1e-47
Identities = 105/265 (39%), Positives = 155/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + + YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein.
Length = 817
Score = 191 bits (466), Expect = 1e-47
Identities = 105/265 (39%), Positives = 155/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + + YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein.
Length = 771
Score = 191 bits (466), Expect = 1e-47
Identities = 105/265 (39%), Positives = 155/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + + YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein.
Length = 830
Score = 191 bits (466), Expect = 1e-47
Identities = 105/265 (39%), Positives = 155/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + + YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein.
Length = 819
Score = 191 bits (466), Expect = 1e-47
Identities = 105/265 (39%), Positives = 155/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + + YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein.
Length = 819
Score = 191 bits (466), Expect = 1e-47
Identities = 105/265 (39%), Positives = 155/265 (58%), Gaps = 19/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V G+ + + +A + VAVK L + +T + SD + E
Sbjct: 479 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA--VTVAVKMLKDDATEKDLSDLVSEM 536
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
+M H NI++L+G C P ++++E + G+L+ +LR RP S
Sbjct: 537 EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPE 596
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
+T KDL+ C+ + + YL +++ IHRD+AARN L+T V+KIADFG+ARDI
Sbjct: 597 EQMTFKDLVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENN---VMKIADFGLARDIN 653
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFGVL+WE+F+LG PY G E+
Sbjct: 654 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEEL 713
Query: 1083 MELVSGGGRLEKPYGEGSEYHKFKR 1107
+L+ G R++KP +E + R
Sbjct: 714 FKLLKEGHRMDKPANCTNELYMMMR 738
>Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor 4
protein.
Length = 802
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 464 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 521
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 522 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 581
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 582 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 638
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 639 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 698
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 699 FSLLREGHRMDRP 711
>X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor
receptor protein.
Length = 802
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 464 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 521
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 522 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 581
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 582 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 638
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 639 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 698
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 699 FSLLREGHRMDRP 711
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 191 bits (465), Expect = 1e-47
Identities = 100/243 (41%), Positives = 149/243 (61%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ L +K +G G FG V+ G +R + + VA+K + E S +E DF+ EA
Sbjct: 265 EIDPSELAFIKEIGSGQFGVVHLGEWR------SHIQVAIKAINEGS--MSEEDFIEEAK 316
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M K +H+ +V L GVC R P +IV E + G L N+LRE++ K + L++ C
Sbjct: 317 VMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSV-----C 371
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
D+C+G YLE +IHRD+AARNCL++S +VKI+DFGM R + +Y G A
Sbjct: 372 Q-DICEGMEYLERNGYIHRDLAARNCLVSSTC---IVKISDFGMTRYVLDDEYVSSFG-A 426
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PPE ++ +++K+DVWSFGVL+WEVF+ G MP+ +N +V+E +S G RL
Sbjct: 427 KFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLY 486
Query: 1094 KPY 1096
+P+
Sbjct: 487 RPH 489
>L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 464 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 521
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 522 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 581
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 582 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 638
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 639 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 698
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 699 FSLLREGHRMDRP 711
>EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 464 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 521
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 522 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 581
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 582 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 638
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 639 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 698
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 699 FSLLREGHRMDRP 711
>BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 464 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 521
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 522 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 581
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 582 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 638
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 639 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 698
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 699 FSLLREGHRMDRP 711
>AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 464 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 521
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 522 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 581
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 582 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 638
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 639 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 698
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 699 FSLLREGHRMDRP 711
>AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth factor
receptor 4 variant protein.
Length = 592
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 254 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 311
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 312 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 371
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 372 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 428
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 429 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 488
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 489 FSLLREGHRMDRP 501
>AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth factor
receptor 4, soluble-form splice variant protein.
Length = 762
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 424 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 481
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 482 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 541
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 542 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 598
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 599 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 658
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 659 FSLLREGHRMDRP 671
>AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth factor
receptor 4 variant protein.
Length = 1034
Score = 191 bits (465), Expect = 1e-47
Identities = 105/253 (41%), Positives = 155/253 (61%), Gaps = 19/253 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQ----GLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEA 912
R+ L L K LG+G FG+V + G+ R A+ VAVK L + ++ + +D + E
Sbjct: 696 RDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQAST--VAVKMLKDNASDKDLADLVSEM 753
Query: 913 AIMAKFN-HANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP-----KPE--RASA 964
+M H NI++L+GVC P ++++E A G+L+ FLR RP P+ R+S
Sbjct: 754 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSE 813
Query: 965 --LTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
L+ L+ C+ V +G +YLE+++ IHRD+AARN L+T V+KIADFG+AR ++
Sbjct: 814 GPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTE---DNVMKIADFGLARGVH 870
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
DYYKK LP+KWM PEA D V+T ++DVWSFG+LLWE+F+LG PY G E+
Sbjct: 871 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEEL 930
Query: 1083 MELVSGGGRLEKP 1095
L+ G R+++P
Sbjct: 931 FSLLREGHRMDRP 943
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 190 bits (464), Expect = 2e-47
Identities = 105/258 (40%), Positives = 149/258 (57%), Gaps = 24/258 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 476 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 535
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL------ 970
+F++ NIV L+GVC P ++ E +A GDL FLR P +L+ DL
Sbjct: 536 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM--SPHTVCSLSHSDLSMRAQV 593
Query: 971 -------LLCSVDVC------KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
L C+ +C G YL ++F+HRD+A RNCL+ G VVKIADFG+
Sbjct: 594 SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGL 650
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
+R+IY ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G
Sbjct: 651 SRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM 710
Query: 1078 ANREVMELVSGGGRLEKP 1095
A+ EV+ V G L P
Sbjct: 711 AHEEVIYYVRDGNILSCP 728
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 190 bits (464), Expect = 2e-47
Identities = 105/258 (40%), Positives = 149/258 (57%), Gaps = 24/258 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 486 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 545
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL------ 970
+F++ NIV L+GVC P ++ E +A GDL FLR P +L+ DL
Sbjct: 546 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM--SPHTVCSLSHSDLSMRAQV 603
Query: 971 -------LLCSVDVC------KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
L C+ +C G YL ++F+HRD+A RNCL+ G VVKIADFG+
Sbjct: 604 SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGL 660
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
+R+IY ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G
Sbjct: 661 SRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM 720
Query: 1078 ANREVMELVSGGGRLEKP 1095
A+ EV+ V G L P
Sbjct: 721 AHEEVIYYVRDGNILSCP 738
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 190 bits (464), Expect = 2e-47
Identities = 105/258 (40%), Positives = 149/258 (57%), Gaps = 24/258 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 570 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 629
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL------ 970
+F++ NIV L+GVC P ++ E +A GDL FLR P +L+ DL
Sbjct: 630 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM--SPHTVCSLSHSDLSMRAQV 687
Query: 971 -------LLCSVDVC------KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
L C+ +C G YL ++F+HRD+A RNCL+ G VVKIADFG+
Sbjct: 688 SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGL 744
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
+R+IY ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G
Sbjct: 745 SRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM 804
Query: 1078 ANREVMELVSGGGRLEKP 1095
A+ EV+ V G L P
Sbjct: 805 AHEEVIYYVRDGNILSCP 822
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 190 bits (464), Expect = 2e-47
Identities = 105/258 (40%), Positives = 149/258 (57%), Gaps = 24/258 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 578 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 637
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL------ 970
+F++ NIV L+GVC P ++ E +A GDL FLR P +L+ DL
Sbjct: 638 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM--SPHTVCSLSHSDLSMRAQV 695
Query: 971 -------LLCSVDVC------KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
L C+ +C G YL ++F+HRD+A RNCL+ G VVKIADFG+
Sbjct: 696 SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGL 752
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
+R+IY ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G
Sbjct: 753 SRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM 812
Query: 1078 ANREVMELVSGGGRLEKP 1095
A+ EV+ V G L P
Sbjct: 813 AHEEVIYYVRDGNILSCP 830
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 190 bits (464), Expect = 2e-47
Identities = 105/258 (40%), Positives = 149/258 (57%), Gaps = 24/258 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 570 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 629
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL------ 970
+F++ NIV L+GVC P ++ E +A GDL FLR P +L+ DL
Sbjct: 630 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM--SPHTVCSLSHSDLSMRAQV 687
Query: 971 -------LLCSVDVC------KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
L C+ +C G YL ++F+HRD+A RNCL+ G VVKIADFG+
Sbjct: 688 SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGL 744
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
+R+IY ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G
Sbjct: 745 SRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM 804
Query: 1078 ANREVMELVSGGGRLEKP 1095
A+ EV+ V G L P
Sbjct: 805 AHEEVIYYVRDGNILSCP 822
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 190 bits (464), Expect = 2e-47
Identities = 105/258 (40%), Positives = 149/258 (57%), Gaps = 24/258 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 578 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 637
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL------ 970
+F++ NIV L+GVC P ++ E +A GDL FLR P +L+ DL
Sbjct: 638 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM--SPHTVCSLSHSDLSMRAQV 695
Query: 971 -------LLCSVDVC------KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
L C+ +C G YL ++F+HRD+A RNCL+ G VVKIADFG+
Sbjct: 696 SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGL 752
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
+R+IY ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G
Sbjct: 753 SRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM 812
Query: 1078 ANREVMELVSGGGRLEKP 1095
A+ EV+ V G L P
Sbjct: 813 AHEEVIYYVRDGNILSCP 830
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 190 bits (464), Expect = 2e-47
Identities = 105/258 (40%), Positives = 149/258 (57%), Gaps = 24/258 (9%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R +++ V+ +G+GAFG V+Q VAVK L E ++ ++DF EAA+MA
Sbjct: 572 RNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMA 631
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDL------ 970
+F++ NIV L+GVC P ++ E +A GDL FLR P +L+ DL
Sbjct: 632 EFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM--SPHTVCSLSHSDLSMRAQV 689
Query: 971 -------LLCSVDVC------KGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGM 1017
L C+ +C G YL ++F+HRD+A RNCL+ G VVKIADFG+
Sbjct: 690 SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV---GENMVVKIADFGL 746
Query: 1018 ARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGC 1077
+R+IY ADYYK +PI+WMPPE+ +TT++DVW++GV+LWE+FS G+ PY G
Sbjct: 747 SRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM 806
Query: 1078 ANREVMELVSGGGRLEKP 1095
A+ EV+ V G L P
Sbjct: 807 AHEEVIYYVRDGNILSCP 824
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 188 bits (459), Expect = 7e-47
Identities = 99/243 (40%), Positives = 148/243 (60%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ L +K +G G FG V+ G +R + + VA+K + E S +E DF+ EA
Sbjct: 265 EIDPSELAFIKXIGSGQFGVVHLGEWR------SHIQVAIKAINEGS--MSEEDFIEEAK 316
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M K +H+ +V L GVC R P +IV E + G L N+LRE++ K + L++ C
Sbjct: 317 VMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSV-----C 371
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+C+G YLE +IHRD+AARNCL++S +VKI+DFGM R + +Y G A
Sbjct: 372 QX-ICEGMEYLERNGYIHRDLAARNCLVSSTC---IVKISDFGMTRYVLDDEYVSSFG-A 426
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PPE ++ +++K+DVWSFGVL+WEVF+ G MP+ +N +V+E +S G RL
Sbjct: 427 KFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLY 486
Query: 1094 KPY 1096
+P+
Sbjct: 487 RPH 489
>M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor
protein.
Length = 885
Score = 188 bits (457), Expect = 1e-46
Identities = 101/248 (40%), Positives = 145/248 (58%), Gaps = 14/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
V R + L K LG+G FG V +G + D + + VAVKT+ + T DFL EA
Sbjct: 522 VDRHKVALGKTLGEGEFGAVMEG---QLNQDDSILKVAVKTMKIAICTRSELEDFLSEAV 578
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H N++ LIGVCF R ++L + GDL +FL SR ++ L
Sbjct: 579 CMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSR-LGDQPVYLPT 637
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ D+ G YL TKRFIHRD+AARNC+L V +ADFG+++ IY DYY
Sbjct: 638 QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNEN---MSVCVADFGLSKKIYNGDYY 694
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G A +P+KW+ E+ D V+T+K+DVWSFGV +WE+ + G PY G N E+ + +
Sbjct: 695 RQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLR 754
Query: 1088 GGGRLEKP 1095
G RL++P
Sbjct: 755 QGNRLKQP 762
>BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine kinase
protein.
Length = 894
Score = 188 bits (457), Expect = 1e-46
Identities = 101/248 (40%), Positives = 145/248 (58%), Gaps = 14/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
V R + L K LG+G FG V +G + D + + VAVKT+ + T DFL EA
Sbjct: 531 VDRHKVALGKTLGEGEFGAVMEG---QLNQDDSILKVAVKTMKIAICTRSELEDFLSEAV 587
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H N++ LIGVCF R ++L + GDL +FL SR ++ L
Sbjct: 588 CMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSR-LGDQPVYLPT 646
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ D+ G YL TKRFIHRD+AARNC+L V +ADFG+++ IY DYY
Sbjct: 647 QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNEN---MSVCVADFGLSKKIYNGDYY 703
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G A +P+KW+ E+ D V+T+K+DVWSFGV +WE+ + G PY G N E+ + +
Sbjct: 704 RQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLR 763
Query: 1088 GGGRLEKP 1095
G RL++P
Sbjct: 764 RGNRLKQP 771
>U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4
protein.
Length = 1070
Score = 187 bits (456), Expect = 2e-46
Identities = 99/255 (38%), Positives = 157/255 (61%), Gaps = 8/255 (3%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R SL+ + LG+ FGEV+ + AE V VK+L + Q + DF E +
Sbjct: 793 RSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFG 851
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCS 974
K NHAN+V L+G+C + P ++VLE + DLK FLR S+ K E+ + L+ K +
Sbjct: 852 KLNHANVVRLLGLCREAEPHYMVLEYVDLEDLKQFLRISKSKDEKLKSQPLSTKQKVALC 911
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
V G +L RF+H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A
Sbjct: 912 TQVALGMEHLSNNRFVHKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAW 967
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLE 1093
+ ++WM PEA ++G F+TK+DVW+ GVL+WEVF+ G MP+ G A+ EV+ +L +G RL
Sbjct: 968 VALRWMSPEAILEGDFSTKSDVWASGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLP 1027
Query: 1094 KPYGEGSEYHKFKRR 1108
+P G S+ ++ +R
Sbjct: 1028 QPEGCPSKLYRLMQR 1042
>X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA for
tyrosine kinase receptor. ).
Length = 894
Score = 186 bits (454), Expect = 3e-46
Identities = 101/248 (40%), Positives = 143/248 (57%), Gaps = 14/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
V R + L K LG+G FG V +G + D + + VAVKT+ + T DFL EA
Sbjct: 531 VDRHKVALGKTLGEGEFGAVMEG---QLNQDDSILKVAVKTMKIAICTRSELEDFLSEAV 587
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H N++ LIGVCF R ++L + GDL +FL SR + T
Sbjct: 588 CMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGGQPVYLPTQ 647
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
L+ D+ G YL TKRFIHRD+AARNC+L V +ADFG+++ IY DYY
Sbjct: 648 M-LVKFMADIASGMEYLSTKRFIHRDLAARNCMLNEN---MSVCVADFGLSKKIYNGDYY 703
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G A +P+KW+ E+ D V+T+K+DVWSFGV +WE+ + G PY G N E+ + +
Sbjct: 704 RQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLR 763
Query: 1088 GGGRLEKP 1095
G RL++P
Sbjct: 764 QGNRLKQP 771
>S65125-1|AAB20305.1| 894|Homo sapiens UFO protein.
Length = 894
Score = 186 bits (454), Expect = 3e-46
Identities = 101/248 (40%), Positives = 143/248 (57%), Gaps = 14/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
V R + L K LG+G FG V +G + D + + VAVKT+ + T DFL EA
Sbjct: 531 VDRHKVALGKTLGEGEFGAVMEG---QLNQDDSILKVAVKTMKIAICTRSELEDFLSEAV 587
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H N++ LIGVCF R ++L + GDL +FL SR + T
Sbjct: 588 CMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGGQPVYLPTQ 647
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
L+ D+ G YL TKRFIHRD+AARNC+L V +ADFG+++ IY DYY
Sbjct: 648 M-LVKFMADIASGMEYLSTKRFIHRDLAARNCMLNEN---MSVCVADFGLSKKIYNGDYY 703
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G A +P+KW+ E+ D V+T+K+DVWSFGV +WE+ + G PY G N E+ + +
Sbjct: 704 RQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLR 763
Query: 1088 GGGRLEKP 1095
G RL++P
Sbjct: 764 QGNRLKQP 771
>S76475-1|AAB33111.1| 839|Homo sapiens trkC protein.
Length = 839
Score = 184 bits (448), Expect = 2e-45
Identities = 104/264 (39%), Positives = 147/264 (55%), Gaps = 27/264 (10%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R + L + LG+GAFG+V+ + S +M VAVK L + T A DF EA +
Sbjct: 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD-PTLAARKDFQREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP--------KPERASA-L 965
+ H +IV GVC D P +V E + GDL FLR P +P +A L
Sbjct: 592 LTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGEL 651
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+ +L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y D
Sbjct: 652 GLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV---GANLLVKIGDFGMSRDVYSTD 708
Query: 1026 YYKK--------------GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGV 1071
YY+ GG MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G
Sbjct: 709 YYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGK 768
Query: 1072 MPYTGCANREVMELVSGGGRLEKP 1095
P+ +N EV+E ++ G LE+P
Sbjct: 769 QPWFQLSNTEVIECITQGRVLERP 792
>BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein.
Length = 940
Score = 184 bits (448), Expect = 2e-45
Identities = 94/238 (39%), Positives = 148/238 (62%), Gaps = 14/238 (5%)
Query: 859 SLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKF 918
+++ ++ LG+ AFG++Y+G D A++ VA+KTL + + Q ++F EA++MA+
Sbjct: 475 AVRFMEELGECAFGKIYKGHLYLPGMDHAQL-VAIKTLKDYNNPQQWTEFQQEASLMAEL 533
Query: 919 NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERA----------SALTMK 968
+H NIV L+G P ++ E + GDL FL P + S+L
Sbjct: 534 HHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHG 593
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
D L ++ + G YL + F+H+D+AARN L+ G VKI+D G++R+IY ADYY+
Sbjct: 594 DFLHIAIQIAAGMEYLSSHFFVHKDLAARNILI---GEQLHVKISDLGLSREIYSADYYR 650
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
K++LPI+WMPPEA + G F++ +D+WSFGV+LWE+FS G+ PY G +N+EV+E+V
Sbjct: 651 VQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMV 708
>AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 184 bits (448), Expect = 2e-45
Identities = 94/238 (39%), Positives = 148/238 (62%), Gaps = 14/238 (5%)
Query: 859 SLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKF 918
+++ ++ LG+ AFG++Y+G D A++ VA+KTL + + Q ++F EA++MA+
Sbjct: 472 AVRFMEELGECAFGKIYKGHLYLPGMDHAQL-VAIKTLKDYNNPQQWTEFQQEASLMAEL 530
Query: 919 NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERA----------SALTMK 968
+H NIV L+G P ++ E + GDL FL P + S+L
Sbjct: 531 HHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHG 590
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
D L ++ + G YL + F+H+D+AARN L+ G VKI+D G++R+IY ADYY+
Sbjct: 591 DFLHIAIQIAAGMEYLSSHFFVHKDLAARNILI---GEQLHVKISDLGLSREIYSADYYR 647
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
K++LPI+WMPPEA + G F++ +D+WSFGV+LWE+FS G+ PY G +N+EV+E+V
Sbjct: 648 VQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMV 705
>AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 184 bits (448), Expect = 2e-45
Identities = 94/238 (39%), Positives = 148/238 (62%), Gaps = 14/238 (5%)
Query: 859 SLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKF 918
+++ ++ LG+ AFG++Y+G D A++ VA+KTL + + Q ++F EA++MA+
Sbjct: 472 AVRFMEELGECAFGKIYKGHLYLPGMDHAQL-VAIKTLKDYNNPQQWTEFQQEASLMAEL 530
Query: 919 NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERA----------SALTMK 968
+H NIV L+G P ++ E + GDL FL P + S+L
Sbjct: 531 HHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHG 590
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
D L ++ + G YL + F+H+D+AARN L+ G VKI+D G++R+IY ADYY+
Sbjct: 591 DFLHIAIQIAAGMEYLSSHFFVHKDLAARNILI---GEQLHVKISDLGLSREIYSADYYR 647
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
K++LPI+WMPPEA + G F++ +D+WSFGV+LWE+FS G+ PY G +N+EV+E+V
Sbjct: 648 VQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMV 705
>AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 184 bits (448), Expect = 2e-45
Identities = 94/238 (39%), Positives = 148/238 (62%), Gaps = 14/238 (5%)
Query: 859 SLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKF 918
+++ ++ LG+ AFG++Y+G D A++ VA+KTL + + Q ++F EA++MA+
Sbjct: 472 AVRFMEELGECAFGKIYKGHLYLPGMDHAQL-VAIKTLKDYNNPQQWTEFQQEASLMAEL 530
Query: 919 NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERA----------SALTMK 968
+H NIV L+G P ++ E + GDL FL P + S+L
Sbjct: 531 HHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHG 590
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
D L ++ + G YL + F+H+D+AARN L+ G VKI+D G++R+IY ADYY+
Sbjct: 591 DFLHIAIQIAAGMEYLSSHFFVHKDLAARNILI---GEQLHVKISDLGLSREIYSADYYR 647
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
K++LPI+WMPPEA + G F++ +D+WSFGV+LWE+FS G+ PY G +N+EV+E+V
Sbjct: 648 VQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMV 705
>AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein.
Length = 839
Score = 184 bits (448), Expect = 2e-45
Identities = 104/264 (39%), Positives = 147/264 (55%), Gaps = 27/264 (10%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ R + L + LG+GAFG+V+ + S +M VAVK L + T A DF EA +
Sbjct: 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD-PTLAARKDFQREAEL 591
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRP--------KPERASA-L 965
+ H +IV GVC D P +V E + GDL FLR P +P +A L
Sbjct: 592 LTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGEL 651
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+ +L + + G YL ++ F+HRD+A RNCL+ G +VKI DFGM+RD+Y D
Sbjct: 652 GLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV---GANLLVKIGDFGMSRDVYSTD 708
Query: 1026 YYKK--------------GGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGV 1071
YY+ GG MLPI+WMPPE+ + FTT++DVWSFGV+LWE+F+ G
Sbjct: 709 YYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGK 768
Query: 1072 MPYTGCANREVMELVSGGGRLEKP 1095
P+ +N EV+E ++ G LE+P
Sbjct: 769 QPWFQLSNTEVIECITQGRVLERP 792
>D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kinase
protein.
Length = 631
Score = 184 bits (447), Expect = 2e-45
Identities = 103/242 (42%), Positives = 140/242 (57%), Gaps = 18/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++ L ++ LG G FG V G +R A+ VA+K + E E DF+ EA
Sbjct: 364 EINPSELTFMRELGSGLFGVVRLGKWR------AQYKVAIKAIRE--GAMCEEDFIEEAK 415
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M K H +V L GVC + P +IV E + G L NFLR+ + R L+M C
Sbjct: 416 VMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSM-----C 470
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+G YLE FIHRD+AARNCL++ G VVK++DFGMAR + D Y A
Sbjct: 471 Q-DVCEGMEYLERNSFIHRDLAARNCLVSEAG---VVKVSDFGMAR-YFLDDQYTSSSGA 525
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P+KW PPE + F++K+DVWSFGVL+WEVF+ G MP+ N EV+ +V+ G RL
Sbjct: 526 KFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLY 585
Query: 1094 KP 1095
+P
Sbjct: 586 QP 587
>M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor
protein.
Length = 937
Score = 183 bits (446), Expect = 3e-45
Identities = 94/238 (39%), Positives = 147/238 (61%), Gaps = 14/238 (5%)
Query: 859 SLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKF 918
+++ ++ LG+ AFG++Y+G D A++ VA+KTL + + Q +F EA++MA+
Sbjct: 472 AVRFMEELGECAFGKIYKGHLYLPGMDHAQL-VAIKTLKDYNNPQQWMEFQQEASLMAEL 530
Query: 919 NHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERA----------SALTMK 968
+H NIV L+G P ++ E + GDL FL P + S+L
Sbjct: 531 HHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHG 590
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
D L ++ + G YL + F+H+D+AARN L+ G VKI+D G++R+IY ADYY+
Sbjct: 591 DFLHIAIQIAAGMEYLSSHFFVHKDLAARNILI---GEQLHVKISDLGLSREIYSADYYR 647
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELV 1086
K++LPI+WMPPEA + G F++ +D+WSFGV+LWE+FS G+ PY G +N+EV+E+V
Sbjct: 648 VQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMV 705
>BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine kinase
protein.
Length = 631
Score = 183 bits (446), Expect = 3e-45
Identities = 103/242 (42%), Positives = 140/242 (57%), Gaps = 18/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++ L ++ LG G FG V G +R A+ VA+K + E E DF+ EA
Sbjct: 364 EINPSELTFMRELGSGLFGVVRLGKWR------AQYKVAIKAIRE--GAMCEEDFIEEAK 415
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M K H +V L GVC + P +IV E + G L NFLR+ + R L+M C
Sbjct: 416 VMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSM-----C 470
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+G YLE FIHRD+AARNCL++ G VVK++DFGMAR + Y G A
Sbjct: 471 Q-DVCEGMEYLERNSFIHRDLAARNCLVSEAG---VVKVSDFGMARYVLDDQYTSSSG-A 525
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P+KW PPE + F++K+DVWSFGVL+WEVF+ G MP+ N EV+ +V+ G RL
Sbjct: 526 KFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLY 585
Query: 1094 KP 1095
+P
Sbjct: 586 QP 587
>BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine kinase
protein.
Length = 631
Score = 183 bits (446), Expect = 3e-45
Identities = 103/242 (42%), Positives = 140/242 (57%), Gaps = 18/242 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
+++ L ++ LG G FG V G +R A+ VA+K + E E DF+ EA
Sbjct: 364 EINPSELTFMRELGSGLFGVVRLGKWR------AQYKVAIKAIRE--GAMCEEDFIEEAK 415
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M K H +V L GVC + P +IV E + G L NFLR+ + R L+M C
Sbjct: 416 VMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSM-----C 470
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+G YLE FIHRD+AARNCL++ G VVK++DFGMAR + Y G A
Sbjct: 471 Q-DVCEGMEYLERNSFIHRDLAARNCLVSEAG---VVKVSDFGMARYVLDDQYTSSSG-A 525
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P+KW PPE + F++K+DVWSFGVL+WEVF+ G MP+ N EV+ +V+ G RL
Sbjct: 526 KFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLY 585
Query: 1094 KP 1095
+P
Sbjct: 586 QP 587
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 447
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 502
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 503 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 557
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 558 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 617
Query: 1094 KPY 1096
+P+
Sbjct: 618 RPH 620
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 447
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 502
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 503 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 557
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 558 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 617
Query: 1094 KPY 1096
+P+
Sbjct: 618 RPH 620
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 394 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 445
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 446 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 500
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 501 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 555
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 556 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 615
Query: 1094 KPY 1096
+P+
Sbjct: 616 RPH 618
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 447
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 502
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 503 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 557
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 558 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 617
Query: 1094 KPY 1096
+P+
Sbjct: 618 RPH 620
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 447
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 502
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 503 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 557
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 558 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 617
Query: 1094 KPY 1096
+P+
Sbjct: 618 RPH 620
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 447
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 502
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 503 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 557
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 558 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 617
Query: 1094 KPY 1096
+P+
Sbjct: 618 RPH 620
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 447
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 502
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 503 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 557
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 558 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 617
Query: 1094 KPY 1096
+P+
Sbjct: 618 RPH 620
>AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 2
protein.
Length = 319
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 67 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 118
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 119 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 173
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 174 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 228
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 229 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 288
Query: 1094 KPY 1096
+P+
Sbjct: 289 RPH 291
>AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein
protein.
Length = 364
Score = 183 bits (445), Expect = 4e-45
Identities = 95/239 (39%), Positives = 150/239 (62%), Gaps = 8/239 (3%)
Query: 873 EVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFD 932
EV+ + AE V VK+L + Q + DF E + K NHAN+V L+G+C +
Sbjct: 103 EVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCRE 161
Query: 933 RHPRFIVLELLAGGDLKNFLRESRPKPERASA--LTMKDLLLCSVDVCKGCRYLETKRFI 990
P ++VLE + GDLK FLR S+ K E+ + L+ K + V G +L RF+
Sbjct: 162 AEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFV 221
Query: 991 HRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVF 1050
H+D+AARNCL++++ R VK++ G+++D+Y ++YY +A +P++WM PEA ++G F
Sbjct: 222 HKDLAARNCLVSAQ---RQVKVSALGLSKDVYNSEYYHFR-QAWVPLRWMSPEAILEGDF 277
Query: 1051 TTKTDVWSFGVLLWEVFSLGVMPYTGCANREVM-ELVSGGGRLEKPYGEGSEYHKFKRR 1108
+TK+DVW+FGVL+WEVF+ G MP+ G A+ EV+ +L +G RL +P G S+ ++ +R
Sbjct: 278 STKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQR 336
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 183 bits (445), Expect = 4e-45
Identities = 96/243 (39%), Positives = 145/243 (59%), Gaps = 18/243 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ + L +K LG G FG V G +R + VA+K + E S +E +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGS--MSEDEFIEEAK 447
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M +H +V L GVC + P FI+ E +A G L N+LRE R + + L M C
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEM-----C 502
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
DVC+ YLE+K+F+HRD+AARNCL+ +G VVK++DFG++R + +Y G +
Sbjct: 503 K-DVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDDEYTSSVG-S 557
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
P++W PPE + F++K+D+W+FGVL+WE++SLG MPY N E E ++ G RL
Sbjct: 558 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY 617
Query: 1094 KPY 1096
+P+
Sbjct: 618 RPH 620
>BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 181 bits (441), Expect = 1e-44
Identities = 94/247 (38%), Positives = 145/247 (58%), Gaps = 12/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE-SDFLMEAA 913
+ R L L K LG+G FG V +G + D + VAVKT+ ++ Q E +FL EAA
Sbjct: 406 IDRNLLILGKILGEGEFGSVMEGNLKQE--DGTSLKVAVKTMKLDNSSQREIEEFLSEAA 463
Query: 914 IMAKFNHANIVHLIGVCFDRHPR-----FIVLELLAGGDLKNFLRESRPKPERASALTMK 968
M F+H N++ L+GVC + + ++L + GDL +L SR + + ++
Sbjct: 464 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETG-PKHIPLQ 522
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
LL VD+ G YL + F+HRD+AARNC+L V +ADFG+++ IY DYY+
Sbjct: 523 TLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRD---DMTVCVADFGLSKKIYSGDYYR 579
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+G A +P+KW+ E+ D V+T+K+DVW+FGV +WE+ + G+ PY G N E+ + +
Sbjct: 580 QGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLH 639
Query: 1089 GGRLEKP 1095
G RL++P
Sbjct: 640 GHRLKQP 646
>BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 181 bits (441), Expect = 1e-44
Identities = 94/247 (38%), Positives = 145/247 (58%), Gaps = 12/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE-SDFLMEAA 913
+ R L L K LG+G FG V +G + D + VAVKT+ ++ Q E +FL EAA
Sbjct: 406 IDRNLLILGKILGEGEFGSVMEGNLKQE--DGTSLKVAVKTMKLDNSSQREIEEFLSEAA 463
Query: 914 IMAKFNHANIVHLIGVCFDRHPR-----FIVLELLAGGDLKNFLRESRPKPERASALTMK 968
M F+H N++ L+GVC + + ++L + GDL +L SR + + ++
Sbjct: 464 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETG-PKHIPLQ 522
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
LL VD+ G YL + F+HRD+AARNC+L V +ADFG+++ IY DYY+
Sbjct: 523 TLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRD---DMTVCVADFGLSKKIYSGDYYR 579
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+G A +P+KW+ E+ D V+T+K+DVW+FGV +WE+ + G+ PY G N E+ + +
Sbjct: 580 QGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLH 639
Query: 1089 GGRLEKP 1095
G RL++P
Sbjct: 640 GHRLKQP 646
>AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine kinase
protein.
Length = 978
Score = 181 bits (441), Expect = 1e-44
Identities = 94/247 (38%), Positives = 145/247 (58%), Gaps = 12/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE-SDFLMEAA 913
+ R L L K LG+G FG V +G + D + VAVKT+ ++ Q E +FL EAA
Sbjct: 561 IDRNLLILGKILGEGEFGSVMEGNLKQE--DGTSLKVAVKTMKLDNSSQREIEEFLSEAA 618
Query: 914 IMAKFNHANIVHLIGVCFDRHPR-----FIVLELLAGGDLKNFLRESRPKPERASALTMK 968
M F+H N++ L+GVC + + ++L + GDL +L SR + + ++
Sbjct: 619 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETG-PKHIPLQ 677
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
LL VD+ G YL + F+HRD+AARNC+L V +ADFG+++ IY DYY+
Sbjct: 678 TLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRD---DMTVCVADFGLSKKIYSGDYYR 734
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+G A +P+KW+ E+ D V+T+K+DVW+FGV +WE+ + G+ PY G N E+ + +
Sbjct: 735 QGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLH 794
Query: 1089 GGRLEKP 1095
G RL++P
Sbjct: 795 GHRLKQP 801
>AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein.
Length = 567
Score = 181 bits (441), Expect = 1e-44
Identities = 94/247 (38%), Positives = 145/247 (58%), Gaps = 12/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE-SDFLMEAA 913
+ R L L K LG+G FG V +G + D + VAVKT+ ++ Q E +FL EAA
Sbjct: 150 IDRNLLILGKILGEGEFGSVMEGNLKQE--DGTSLKVAVKTMKLDNSSQREIEEFLSEAA 207
Query: 914 IMAKFNHANIVHLIGVCFDRHPR-----FIVLELLAGGDLKNFLRESRPKPERASALTMK 968
M F+H N++ L+GVC + + ++L + GDL +L SR + + ++
Sbjct: 208 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETG-PKHIPLQ 266
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
LL VD+ G YL + F+HRD+AARNC+L V +ADFG+++ IY DYY+
Sbjct: 267 TLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRD---DMTVCVADFGLSKKIYSGDYYR 323
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+G A +P+KW+ E+ D V+T+K+DVW+FGV +WE+ + G+ PY G N E+ + +
Sbjct: 324 QGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLH 383
Query: 1089 GGRLEKP 1095
G RL++P
Sbjct: 384 GHRLKQP 390
>U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein.
Length = 999
Score = 179 bits (435), Expect = 6e-44
Identities = 93/247 (37%), Positives = 144/247 (58%), Gaps = 12/247 (4%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE-SDFLMEAA 913
+ R L L K LG+G FG V +G + D + VAVKT+ ++ E +FL EAA
Sbjct: 582 IDRNLLILGKILGEGEFGSVMEGNLKQE--DGTSLKVAVKTMKLDNSSHREIEEFLSEAA 639
Query: 914 IMAKFNHANIVHLIGVCFDRHPR-----FIVLELLAGGDLKNFLRESRPKPERASALTMK 968
M F+H N++ L+GVC + + ++L + GDL +L SR + + ++
Sbjct: 640 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETG-PKHIPLQ 698
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
LL VD+ G YL + F+HRD+AARNC+L V +ADFG+++ IY DYY+
Sbjct: 699 TLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRD---DMTVCVADFGLSKKIYSGDYYR 755
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
+G A +P+KW+ E+ D V+T+K+DVW+FGV +WE+ + G+ PY G N E+ + +
Sbjct: 756 QGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIRTRGMTPYPGVQNHEMYDYLLH 815
Query: 1089 GGRLEKP 1095
G RL++P
Sbjct: 816 GHRLKQP 822
>AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens cDNA
FLJ37680 fis, clone BRHIP2012923, highly similar to FOCAL
ADHESION KINASE 1 (EC 2.7.1.112). ).
Length = 720
Score = 178 bits (434), Expect = 8e-44
Identities = 98/250 (39%), Positives = 148/250 (59%), Gaps = 13/250 (5%)
Query: 846 GIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE 905
GID ++ RE ++L + +G+G FG+V+QG+Y S + + VA+KT ++
Sbjct: 76 GIDEARDYEIQRERIELGRCIGEGQFGDVHQGIYM--SPENPALAVAIKTCKNCTSDSVR 133
Query: 906 SDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL 965
FL EA M +F+H +IV LIGV + +P +I++EL G+L++FL+ R +L
Sbjct: 134 EKFLQEALTMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQV------RKYSL 186
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+ L+L + + YLE+KRF+HRDIAARN L++S VK+ DFG++R + +
Sbjct: 187 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYMEDST 243
Query: 1026 YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMEL 1085
YYK K LPIKWM PE+ FT+ +DVW FGV +WE+ GV P+ G N +V+
Sbjct: 244 YYK-ASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 302
Query: 1086 VSGGGRLEKP 1095
+ G RL P
Sbjct: 303 IENGERLPMP 312
>AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine kinase
2 isoform b variant protein.
Length = 1007
Score = 178 bits (434), Expect = 8e-44
Identities = 98/250 (39%), Positives = 148/250 (59%), Gaps = 13/250 (5%)
Query: 846 GIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE 905
GID ++ RE ++L + +G+G FG+V+QG+Y S + + VA+KT ++
Sbjct: 360 GIDEARDYEIQRERIELGRCIGEGQFGDVHQGIYM--SPENPALAVAIKTCKNCTSDSVR 417
Query: 906 SDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL 965
FL EA M +F+H +IV LIGV + +P +I++EL G+L++FL+ R +L
Sbjct: 418 EKFLQEALTMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQV------RKYSL 470
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+ L+L + + YLE+KRF+HRDIAARN L++S VK+ DFG++R + +
Sbjct: 471 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYMEDST 527
Query: 1026 YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMEL 1085
YYK K LPIKWM PE+ FT+ +DVW FGV +WE+ GV P+ G N +V+
Sbjct: 528 YYK-ASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 586
Query: 1086 VSGGGRLEKP 1095
+ G RL P
Sbjct: 587 IENGERLPMP 596
>AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine kinase
2 isoform b variant protein.
Length = 975
Score = 178 bits (434), Expect = 8e-44
Identities = 98/250 (39%), Positives = 148/250 (59%), Gaps = 13/250 (5%)
Query: 846 GIDVRGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAE 905
GID ++ RE ++L + +G+G FG+V+QG+Y S + + VA+KT ++
Sbjct: 328 GIDEARDYEIQRERIELGRCIGEGQFGDVHQGIYM--SPENPALAVAIKTCKNCTSDSVR 385
Query: 906 SDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASAL 965
FL EA M +F+H +IV LIGV + +P +I++EL G+L++FL+ R +L
Sbjct: 386 EKFLQEALTMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQV------RKYSL 438
Query: 966 TMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRAD 1025
+ L+L + + YLE+KRF+HRDIAARN L++S VK+ DFG++R + +
Sbjct: 439 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYMEDST 495
Query: 1026 YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMEL 1085
YYK K LPIKWM PE+ FT+ +DVW FGV +WE+ GV P+ G N +V+
Sbjct: 496 YYK-ASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 554
Query: 1086 VSGGGRLEKP 1095
+ G RL P
Sbjct: 555 IENGERLPMP 564
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 334
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 335 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 389
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 390 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 445
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 446 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 505
Query: 1094 KPYG 1097
+P G
Sbjct: 506 QPEG 509
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 334
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 335 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 389
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 390 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 445
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 446 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 505
Query: 1094 KPYG 1097
+P G
Sbjct: 506 QPEG 509
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 295 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 347
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 348 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 402
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 403 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 458
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 459 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 518
Query: 1094 KPYG 1097
+P G
Sbjct: 519 QPEG 522
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 267 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 319
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 320 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 374
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 375 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 430
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 431 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 490
Query: 1094 KPYG 1097
+P G
Sbjct: 491 QPEG 494
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 334
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 335 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 389
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 390 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 445
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 446 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 505
Query: 1094 KPYG 1097
+P G
Sbjct: 506 QPEG 509
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 267 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 319
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 320 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 374
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 375 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 430
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 431 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 490
Query: 1094 KPYG 1097
+P G
Sbjct: 491 QPEG 494
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 334
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 335 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 389
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 390 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 445
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 446 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 505
Query: 1094 KPYG 1097
+P G
Sbjct: 506 QPEG 509
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 267 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 319
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 320 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 374
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 375 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 430
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 431 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 490
Query: 1094 KPYG 1097
+P G
Sbjct: 491 QPEG 494
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 334
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 335 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 389
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 390 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 445
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 446 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 505
Query: 1094 KPYG 1097
+P G
Sbjct: 506 QPEG 509
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 177 bits (432), Expect = 1e-43
Identities = 101/244 (41%), Positives = 143/244 (58%), Gaps = 16/244 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 267 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 319
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +IV E + G+L ++LRE E +A+ LL
Sbjct: 320 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNR--EEVTAVV---LLYM 374
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G VVK+ADFG++R + D Y A
Sbjct: 375 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHVVKVADFGLSR-LMTGDTYTAHAGA 430
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V +L+ G R+E
Sbjct: 431 KFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME 490
Query: 1094 KPYG 1097
+P G
Sbjct: 491 QPEG 494
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 288
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 289 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 343
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 344 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 399
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 400 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 459
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 460 RPEGCPEKVYELMR 473
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 288
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 289 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 343
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 344 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 399
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 400 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 459
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 460 RPEGCPEKVYELMR 473
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 307
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 308 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 362
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 363 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 418
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 419 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 478
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 479 RPEGCPEKVYELMR 492
>L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase protein.
Length = 1052
Score = 177 bits (430), Expect = 2e-43
Identities = 95/242 (39%), Positives = 145/242 (59%), Gaps = 13/242 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ RE ++L + +G+G FG+V+QG+Y S + + VA+KT ++ FL EA
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYM--SPENPALAVAIKTCKNCTSDSVREKFLQEAL 473
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
M +F+H +IV LIGV + +P +I++EL G+L++FL+ R +L + L+L
Sbjct: 474 TMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQV------RKYSLDLASLILY 526
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE+KRF+HRDIAARN L++S VK+ DFG++R + + YYK K
Sbjct: 527 AYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYMEDSTYYK-ASKG 582
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LPIKWM PE+ FT+ +DVW FGV +WE+ GV P+ G N +V+ + G RL
Sbjct: 583 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 642
Query: 1094 KP 1095
P
Sbjct: 643 MP 644
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 307
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 308 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 362
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 363 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 418
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 419 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 478
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 479 RPEGCPEKVYELMR 492
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 307
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 308 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 362
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 363 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 418
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 419 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 478
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 479 RPEGCPEKVYELMR 492
>BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein.
Length = 1006
Score = 177 bits (430), Expect = 2e-43
Identities = 95/242 (39%), Positives = 145/242 (59%), Gaps = 13/242 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ RE ++L + +G+G FG+V+QG+Y S + + VA+KT ++ FL EA
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYM--SPENPALAVAIKTCKNCTSDSVREKFLQEAL 473
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
M +F+H +IV LIGV + +P +I++EL G+L++FL+ R +L + L+L
Sbjct: 474 TMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQV------RKYSLDLASLILY 526
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE+KRF+HRDIAARN L++S VK+ DFG++R + + YYK K
Sbjct: 527 AYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYMEDSTYYK-ASKG 582
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LPIKWM PE+ FT+ +DVW FGV +WE+ GV P+ G N +V+ + G RL
Sbjct: 583 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 642
Query: 1094 KP 1095
P
Sbjct: 643 MP 644
>BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein.
Length = 680
Score = 177 bits (430), Expect = 2e-43
Identities = 95/242 (39%), Positives = 145/242 (59%), Gaps = 13/242 (5%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ RE ++L + +G+G FG+V+QG+Y S + + VA+KT ++ FL EA
Sbjct: 44 EIQRERIELGRCIGEGQFGDVHQGIYM--SPENPALAVAIKTCKNCTSDSVREKFLQEAL 101
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
M +F+H +IV LIGV + +P +I++EL G+L++FL+ R +L + L+L
Sbjct: 102 TMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQV------RKYSLDLASLILY 154
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE+KRF+HRDIAARN L++S VK+ DFG++R + + YYK K
Sbjct: 155 AYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYMEDSTYYK-ASKG 210
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
LPIKWM PE+ FT+ +DVW FGV +WE+ GV P+ G N +V+ + G RL
Sbjct: 211 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 270
Query: 1094 KP 1095
P
Sbjct: 271 MP 272
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 307
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 308 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 362
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 363 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 418
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 419 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 478
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 479 RPEGCPEKVYELMR 492
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 307
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 308 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 362
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 363 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 418
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 419 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 478
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 479 RPEGCPEKVYELMR 492
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 288
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 289 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 343
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 344 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 399
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 400 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 459
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 460 RPEGCPEKVYELMR 473
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 177 bits (430), Expect = 2e-43
Identities = 99/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 273 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 325
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 326 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 380
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 381 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 436
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E
Sbjct: 437 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 496
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 497 RPEGCPEKVYELMR 510
>X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein.
Length = 435
Score = 176 bits (429), Expect = 3e-43
Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 84 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 143
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 144 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 203
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 204 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 260
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 261 DVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 320
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 321 ERLFNLLKTGHRMERPDNCSEEMYR 345
>X15786-1|CAA33787.1| 899|Homo sapiens retII protein.
Length = 899
Score = 176 bits (429), Expect = 3e-43
Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 506 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 565
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 566 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 625
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 626 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 682
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 683 DVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 742
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 743 ERLFNLLKTGHRMERPDNCSEEMYR 767
>X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret
proto-oncogene mRNA for tyrosine kinase. ).
Length = 860
Score = 176 bits (429), Expect = 3e-43
Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 467 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 526
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 527 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 586
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 587 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 643
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 644 DVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 703
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 704 ERLFNLLKTGHRMERPDNCSEEMYR 728
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 176 bits (429), Expect = 3e-43
Identities = 98/254 (38%), Positives = 145/254 (57%), Gaps = 16/254 (6%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R + + LG G +GEVY+G+++ S + VAVKTL E T + E +FL EAA
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAA 288
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
+M + H N+V L+GVC P +I+ E + G+L ++LRE + A L L
Sbjct: 289 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYM 343
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKA 1033
+ + YLE K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A
Sbjct: 344 ATQISSAMEYLEKKNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGA 399
Query: 1034 MLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLE 1093
PIKW PE+ F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R++
Sbjct: 400 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDRSQVYELLEKDYRMK 459
Query: 1094 KPYGEGSEYHKFKR 1107
+P G + ++ R
Sbjct: 460 RPEGCPEKVYELMR 473
>DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protein
protein.
Length = 776
Score = 176 bits (429), Expect = 3e-43
Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 383 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 442
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 443 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 502
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 503 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 559
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 560 DVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 619
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 620 ERLFNLLKTGHRMERPDNCSEEMYR 644
>M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA
encoding a tyrosine kinase, partial cds. ).
Length = 805
Score = 176 bits (428), Expect = 4e-43
Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 454 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 513
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 514 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 573
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 574 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 630
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 631 DVYEEDPYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 690
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 691 ERLFNLLKTGHRMERPDNCSEEMYR 715
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 176 bits (428), Expect = 4e-43
Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 245 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 304
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 305 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 364
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 365 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 421
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 422 DVYEEDPYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 481
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 482 ERLFNLLKTGHRMERPDNCSEEMYR 506
>BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene protein.
Length = 1072
Score = 176 bits (428), Expect = 4e-43
Identities = 97/256 (37%), Positives = 142/256 (55%), Gaps = 20/256 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 721 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 780
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 781 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 840
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 841 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 897
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 898 DVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 957
Query: 1080 REVMELVSGGGRLEKP 1095
+ L+ G R+E+P
Sbjct: 958 ERLFNLLKTGHRMERP 973
>M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary
thyroid carcinoma-encoded protein mRNA, complete cds. ).
Length = 503
Score = 175 bits (425), Expect = 1e-42
Identities = 97/265 (36%), Positives = 144/265 (54%), Gaps = 20/265 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H VAVK L E ++ D L E ++
Sbjct: 110 RKNLVLGKTLGEGEFGKVVKATAFHLKGRGGYTTVAVKMLKENASPSELRDLLSEFNVLK 169
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 170 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 229
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 230 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 286
Query: 1020 DIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCAN 1079
D+Y D Y K + +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 287 DVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 346
Query: 1080 REVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 347 ERLFNLLKTGHRMERPDNCSEEMYR 371
>U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein
protein.
Length = 523
Score = 173 bits (420), Expect = 4e-42
Identities = 95/235 (40%), Positives = 135/235 (57%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G D ++ AVK+L ++ S FL E IM F+H N+
Sbjct: 215 EVIGRGHFGCVYHGTLLDN--DGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 272
Query: 924 VHLIGVCF-DRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+G+C +VL + GDL+NF+R P T+KDL+ + V KG +
Sbjct: 273 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNP------TVKDLIGFGLQVAKGMK 326
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK--AMLPIKWM 1040
YL +K+F+HRD+AARNC+L + VK+ADFG+ARD+Y +YY K A LP+KWM
Sbjct: 327 YLASKKFVHRDLAARNCMLDEKF---TVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM 383
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGVLLWE+ + G PY ++ + G RL +P
Sbjct: 384 ALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP 438
>U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene
protein.
Length = 455
Score = 173 bits (420), Expect = 4e-42
Identities = 95/235 (40%), Positives = 135/235 (57%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G D ++ AVK+L ++ S FL E IM F+H N+
Sbjct: 147 EVIGRGHFGCVYHGTLLDN--DGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 204
Query: 924 VHLIGVCF-DRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+G+C +VL + GDL+NF+R P T+KDL+ + V KG +
Sbjct: 205 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNP------TVKDLIGFGLQVAKGMK 258
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK--AMLPIKWM 1040
YL +K+F+HRD+AARNC+L + VK+ADFG+ARD+Y +YY K A LP+KWM
Sbjct: 259 YLASKKFVHRDLAARNCMLDEKF---TVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM 315
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGVLLWE+ + G PY ++ + G RL +P
Sbjct: 316 ALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP 370
>BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene
(hepatocyte growth factor receptor) protein.
Length = 1390
Score = 173 bits (420), Expect = 4e-42
Identities = 95/235 (40%), Positives = 135/235 (57%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G D ++ AVK+L ++ S FL E IM F+H N+
Sbjct: 1082 EVIGRGHFGCVYHGTLLDN--DGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query: 924 VHLIGVCF-DRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+G+C +VL + GDL+NF+R P T+KDL+ + V KG +
Sbjct: 1140 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNP------TVKDLIGFGLQVAKGMK 1193
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK--AMLPIKWM 1040
YL +K+F+HRD+AARNC+L + VK+ADFG+ARD+Y +YY K A LP+KWM
Sbjct: 1194 YLASKKFVHRDLAARNCMLDEKF---TVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM 1250
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGVLLWE+ + G PY ++ + G RL +P
Sbjct: 1251 ALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP 1305
>AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase receptor
protein.
Length = 1091
Score = 173 bits (420), Expect = 4e-42
Identities = 98/266 (36%), Positives = 145/266 (54%), Gaps = 21/266 (7%)
Query: 857 RESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMA 916
R++L L K LG+G FG+V + H A VAVK L E ++ D L E ++
Sbjct: 697 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 756
Query: 917 KFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKP--------ERAS----- 963
+ NH +++ L G C P +++E G L+ FLRESR R S
Sbjct: 757 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 816
Query: 964 ----ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR 1019
ALTM DL+ + + +G +YL + +HRD+AARN L+ GR +KI+DFG++R
Sbjct: 817 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE---GRKMKISDFGLSR 873
Query: 1020 DIYRAD-YYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCA 1078
D+Y D Y K+ +P+KWM E+ D ++TT++DVWSFGVLLWE+ +LG PY G
Sbjct: 874 DVYEEDSYVKRSQVGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIP 933
Query: 1079 NREVMELVSGGGRLEKPYGEGSEYHK 1104
+ L+ G R+E+P E ++
Sbjct: 934 PERLFNLLKTGHRMERPDNCSEEMYR 959
>AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene precursor
variant protein.
Length = 712
Score = 173 bits (420), Expect = 4e-42
Identities = 95/235 (40%), Positives = 135/235 (57%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G D ++ AVK+L ++ S FL E IM F+H N+
Sbjct: 404 EVIGRGHFGCVYHGTLLDN--DGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 461
Query: 924 VHLIGVCF-DRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+G+C +VL + GDL+NF+R P T+KDL+ + V KG +
Sbjct: 462 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNP------TVKDLIGFGLQVAKGMK 515
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK--AMLPIKWM 1040
YL +K+F+HRD+AARNC+L + VK+ADFG+ARD+Y +YY K A LP+KWM
Sbjct: 516 YLASKKFVHRDLAARNCMLDEKF---TVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM 572
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGVLLWE+ + G PY ++ + G RL +P
Sbjct: 573 ALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP 627
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 173 bits (420), Expect = 4e-42
Identities = 97/241 (40%), Positives = 139/241 (57%), Gaps = 16/241 (6%)
Query: 867 GQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHL 926
G G +GEVY+G+++ S + VAVKTL E T + E +FL EAA+M + H N+V L
Sbjct: 68 GGGQYGEVYEGVWKKYS-----LTVAVKTLKE-DTMEVE-EFLKEAAVMKEIKHPNLVQL 120
Query: 927 IGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLET 986
+GVC P +I+ E + G+L ++LRE + A L L + + YLE
Sbjct: 121 LGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL-----LYMATQISSAMEYLEK 175
Query: 987 KRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYI 1046
K FIHRD+AARNCL+ G +VK+ADFG++R + D Y A PIKW PE+
Sbjct: 176 KNFIHRDLAARNCLV---GENHLVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLA 231
Query: 1047 DGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKPYGEGSEYHKFK 1106
F+ K+DVW+FGVLLWE+ + G+ PY G +V EL+ R+E+P G + ++
Sbjct: 232 YNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELM 291
Query: 1107 R 1107
R
Sbjct: 292 R 292
>U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta
protein.
Length = 1009
Score = 172 bits (418), Expect = 7e-42
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 414 GGPQYGIAREDVVLNRILGEGLFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 471
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 472 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 524
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 525 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 581
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 582 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 640
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 641 GDRLPKP 647
>X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein.
Length = 1390
Score = 171 bits (417), Expect = 9e-42
Identities = 94/235 (40%), Positives = 135/235 (57%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G D ++ AVK+L ++ S FL E IM F+H N+
Sbjct: 1082 EVIGRGHFGCVYHGTLLDN--DGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query: 924 VHLIGVCF-DRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+G+C +VL + GDL+NF+R P T+KDL+ + V KG +
Sbjct: 1140 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNP------TVKDLIGFGLQVAKGMK 1193
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK--AMLPIKWM 1040
YL +K+F+HRD+AARNC+L + VK+ADFG+ARD+Y +YY K A LP+KWM
Sbjct: 1194 YLASKKFVHRDLAARNCMLDEKF---TVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM 1250
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGV+LWE+ + G PY ++ + G RL +P
Sbjct: 1251 ALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP 1305
>U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein.
Length = 1009
Score = 171 bits (417), Expect = 9e-42
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 414 GGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 471
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 472 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 524
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 525 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 581
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 582 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 640
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 641 GDRLPKP 647
>S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal
tyrosine kinase protein.
Length = 1009
Score = 171 bits (417), Expect = 9e-42
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 414 GGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 471
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 472 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 524
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 525 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 581
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 582 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 640
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 641 GDRLPKP 647
>L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase protein.
Length = 1009
Score = 171 bits (417), Expect = 9e-42
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 414 GGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 471
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 472 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 524
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 525 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 581
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 582 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 640
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 641 GDRLPKP 647
>BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 171 bits (417), Expect = 9e-42
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 414 GGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 471
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 472 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 524
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 525 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 581
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 582 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 640
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 641 GDRLPKP 647
>BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 171 bits (417), Expect = 9e-42
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 414 GGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 471
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 472 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 524
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 525 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 581
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 582 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 640
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 641 GDRLPKP 647
>AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens cDNA
FLJ46514 fis, clone THYMU3032798, highly similar to
Focal adhesion kinase 2 (EC 2.7.1.112). ).
Length = 596
Score = 171 bits (417), Expect = 9e-42
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 160 GGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 217
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 218 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 270
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 271 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 327
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 328 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 386
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 387 GDRLPKP 393
>AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine
kinase 2 beta isoform a variant protein.
Length = 802
Score = 171 bits (417), Expect = 9e-42
Identities = 97/247 (39%), Positives = 145/247 (58%), Gaps = 15/247 (6%)
Query: 851 GLPQ--VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDF 908
G PQ ++RE + L + LG+G FGEVY+G+Y + + ++ VAVKT + T + F
Sbjct: 419 GGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE--KINVAVKTCKKDCTLDNKEKF 476
Query: 909 LMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMK 968
+ EA IM +H +IV LIG+ + P +I++EL G+L ++L ++ ++L +
Sbjct: 477 MSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNK------NSLKVL 529
Query: 969 DLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYK 1028
L+L S+ +CK YLE+ +HRDIA RN L+ S VK+ DFG++R I DYYK
Sbjct: 530 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASP---ECVKLGDFGLSRYIEDEDYYK 586
Query: 1029 KGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSG 1088
LPIKWM PE+ FTT +DVW F V +WE+ S G P+ N++V+ ++
Sbjct: 587 -ASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK 645
Query: 1089 GGRLEKP 1095
G RL KP
Sbjct: 646 GDRLPKP 652
>X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase
protein.
Length = 855
Score = 171 bits (416), Expect = 1e-41
Identities = 96/257 (37%), Positives = 145/257 (56%), Gaps = 19/257 (7%)
Query: 843 LPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY----QGLYRHRSAD-----AAEMPV-- 891
L G DV + + R+ L + LG+G FGEV+ +G+ + + D +A PV
Sbjct: 547 LLSGKDV-AVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLV 605
Query: 892 AVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNF 951
AVK L + A +DFL E IM++ NI+HL+ VC P ++ E + GDL F
Sbjct: 606 AVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLSVCITDDPLCMITEYMENGDLNQF 665
Query: 952 LRESRPKPERAS---ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGR 1008
L P +S ++ +L + + G +YL + F+HRD+A RNCL+ G
Sbjct: 666 LSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV---GKNY 722
Query: 1009 VVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFS 1068
+KIADFGM+R++Y DYY+ G+A+LPI+WM E+ + G FTT +DVW+FGV LWE F+
Sbjct: 723 TIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFT 782
Query: 1069 L-GVMPYTGCANREVME 1084
PY+ ++ +V+E
Sbjct: 783 FCQEQPYSQLSDEQVIE 799
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 171 bits (416), Expect = 1e-41
Identities = 95/241 (39%), Positives = 136/241 (56%), Gaps = 18/241 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ L V+ +G G FG V+ G + ++ VA+KT+ E +E DF+ EA +
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDK------VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M K +H +V L GVC ++ P +V E + G L ++LR R + LL
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMC 463
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+DVC+G YLE IHRD+AARNCL+ G +V+K++DFGM R + Y G
Sbjct: 464 LDVCEGMAYLEEACVIHRDLAARNCLV---GENQVIKVSDFGMTRFVLDDQYTSSTG-TK 519
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
P+KW PE + +++K+DVWSFGVL+WEVFS G +PY +N EV+E +S G RL K
Sbjct: 520 FPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYK 579
Query: 1095 P 1095
P
Sbjct: 580 P 580
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 171 bits (416), Expect = 1e-41
Identities = 95/241 (39%), Positives = 136/241 (56%), Gaps = 18/241 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ L V+ +G G FG V+ G + ++ VA+KT+ E +E DF+ EA +
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDK------VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M K +H +V L GVC ++ P +V E + G L ++LR R + LL
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMC 463
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+DVC+G YLE IHRD+AARNCL+ G +V+K++DFGM R + Y G
Sbjct: 464 LDVCEGMAYLEEACVIHRDLAARNCLV---GENQVIKVSDFGMTRFVLDDQYTSSTG-TK 519
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
P+KW PE + +++K+DVWSFGVL+WEVFS G +PY +N EV+E +S G RL K
Sbjct: 520 FPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYK 579
Query: 1095 P 1095
P
Sbjct: 580 P 580
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 171 bits (416), Expect = 1e-41
Identities = 95/241 (39%), Positives = 136/241 (56%), Gaps = 18/241 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ L V+ +G G FG V+ G + ++ VA+KT+ E +E DF+ EA +
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDK------VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M K +H +V L GVC ++ P +V E + G L ++LR R + LL
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMC 463
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+DVC+G YLE IHRD+AARNCL+ G +V+K++DFGM R + Y G
Sbjct: 464 LDVCEGMAYLEEACVIHRDLAARNCLV---GENQVIKVSDFGMTRFVLDDQYTSSTG-TK 519
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
P+KW PE + +++K+DVWSFGVL+WEVFS G +PY +N EV+E +S G RL K
Sbjct: 520 FPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYK 579
Query: 1095 P 1095
P
Sbjct: 580 P 580
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell kinase
protein.
Length = 620
Score = 171 bits (416), Expect = 1e-41
Identities = 95/241 (39%), Positives = 136/241 (56%), Gaps = 18/241 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ L V+ +G G FG V+ G + ++ VA+KT+ E +E DF+ EA +
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDK------VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M K +H +V L GVC ++ P +V E + G L ++LR R + LL
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMC 463
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+DVC+G YLE IHRD+AARNCL+ G +V+K++DFGM R + Y G
Sbjct: 464 LDVCEGMAYLEEACVIHRDLAARNCLV---GENQVIKVSDFGMTRFVLDDQYTSSTG-TK 519
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
P+KW PE + +++K+DVWSFGVL+WEVFS G +PY +N EV+E +S G RL K
Sbjct: 520 FPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYK 579
Query: 1095 P 1095
P
Sbjct: 580 P 580
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell kinase
protein.
Length = 620
Score = 171 bits (416), Expect = 1e-41
Identities = 95/241 (39%), Positives = 136/241 (56%), Gaps = 18/241 (7%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAI 914
+ L V+ +G G FG V+ G + ++ VA+KT+ E +E DF+ EA +
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDK------VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 915 MAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCS 974
M K +H +V L GVC ++ P +V E + G L ++LR R + LL
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQR------GLFAAETLLGMC 463
Query: 975 VDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGKAM 1034
+DVC+G YLE IHRD+AARNCL+ G +V+K++DFGM R + Y G
Sbjct: 464 LDVCEGMAYLEEACVIHRDLAARNCLV---GENQVIKVSDFGMTRFVLDDQYTSSTG-TK 519
Query: 1035 LPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEK 1094
P+KW PE + +++K+DVWSFGVL+WEVFS G +PY +N EV+E +S G RL K
Sbjct: 520 FPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYK 579
Query: 1095 P 1095
P
Sbjct: 580 P 580
>BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain receptor
family, member 2 protein.
Length = 855
Score = 171 bits (416), Expect = 1e-41
Identities = 96/257 (37%), Positives = 145/257 (56%), Gaps = 19/257 (7%)
Query: 843 LPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY----QGLYRHRSAD-----AAEMPV-- 891
L G DV + + R+ L + LG+G FGEV+ +G+ + + D +A PV
Sbjct: 547 LLSGKDV-AVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLV 605
Query: 892 AVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNF 951
AVK L + A +DFL E IM++ NI+HL+ VC P ++ E + GDL F
Sbjct: 606 AVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQF 665
Query: 952 LRESRPKPERAS---ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGR 1008
L P +S ++ +L + + G +YL + F+HRD+A RNCL+ G
Sbjct: 666 LSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV---GKNY 722
Query: 1009 VVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFS 1068
+KIADFGM+R++Y DYY+ G+A+LPI+WM E+ + G FTT +DVW+FGV LWE F+
Sbjct: 723 TIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFT 782
Query: 1069 L-GVMPYTGCANREVME 1084
PY+ ++ +V+E
Sbjct: 783 FCQEQPYSQLSDEQVIE 799
>AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain receptor
family, member 2 protein.
Length = 855
Score = 171 bits (416), Expect = 1e-41
Identities = 96/257 (37%), Positives = 145/257 (56%), Gaps = 19/257 (7%)
Query: 843 LPQGIDVRGLPQVSRESLKLVKALGQGAFGEVY----QGLYRHRSAD-----AAEMPV-- 891
L G DV + + R+ L + LG+G FGEV+ +G+ + + D +A PV
Sbjct: 547 LLSGKDV-AVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLV 605
Query: 892 AVKTLPELSTGQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNF 951
AVK L + A +DFL E IM++ NI+HL+ VC P ++ E + GDL F
Sbjct: 606 AVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQF 665
Query: 952 LRESRPKPERAS---ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGR 1008
L P +S ++ +L + + G +YL + F+HRD+A RNCL+ G
Sbjct: 666 LSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV---GKNY 722
Query: 1009 VVKIADFGMARDIYRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFS 1068
+KIADFGM+R++Y DYY+ G+A+LPI+WM E+ + G FTT +DVW+FGV LWE F+
Sbjct: 723 TIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFT 782
Query: 1069 L-GVMPYTGCANREVME 1084
PY+ ++ +V+E
Sbjct: 783 FCQEQPYSQLSDEQVIE 799
>J02958-1|AAA59591.1| 1408|Homo sapiens MET protein.
Length = 1408
Score = 169 bits (411), Expect = 5e-41
Identities = 93/235 (39%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
+ +G+G FG VY G D ++ AVK+L ++ S FL E IM F+H N+
Sbjct: 1100 EVIGRGHFGCVYHGTLLDN--DGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1157
Query: 924 VHLIGVCF-DRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCR 982
+ L+G+C +VL + GDL+NF+R P T+KDL+ + V K +
Sbjct: 1158 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNP------TVKDLIGFGLQVAKAMK 1211
Query: 983 YLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYYKKGGK--AMLPIKWM 1040
YL +K+F+HRD+AARNC+L + VK+ADFG+ARD+Y +YY K A LP+KWM
Sbjct: 1212 YLASKKFVHRDLAARNCMLDEKF---TVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWM 1268
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
E+ FTTK+DVWSFGV+LWE+ + G PY ++ + G RL +P
Sbjct: 1269 ALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP 1323
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 169 bits (410), Expect = 6e-41
Identities = 95/232 (40%), Positives = 129/232 (55%), Gaps = 15/232 (6%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVH 925
+G+G FGEVY+G R S D VA+KTL + S G +FL EA IM +F+H +I+H
Sbjct: 345 IGEGEFGEVYRGTLRLPSQDCKT--VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 402
Query: 926 LIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLE 985
L GV R P I+ E + G L FLRE R L L+ + G YL
Sbjct: 403 LEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQLVAMLQGIASGMNYLS 456
Query: 986 TKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGGKAMLPIKWMPPE 1043
++HRD+AARN L+ K++DFG+ R D + Y +GGK +PI+W PE
Sbjct: 457 NHNYVHRDLAARNILVNQN---LCCKVSDFGLTRLLDDFDGTYETQGGK--IPIRWTAPE 511
Query: 1044 AYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
A +FTT +DVWSFG+++WEV S G PY +N+EVM+ + G RL P
Sbjct: 512 AIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPP 563
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 169 bits (410), Expect = 6e-41
Identities = 95/232 (40%), Positives = 129/232 (55%), Gaps = 15/232 (6%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVH 925
+G+G FGEVY+G R S D VA+KTL + S G +FL EA IM +F+H +I+H
Sbjct: 630 IGEGEFGEVYRGTLRLPSQDCKT--VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query: 926 LIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLE 985
L GV R P I+ E + G L FLRE R L L+ + G YL
Sbjct: 688 LEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQLVAMLQGIASGMNYLS 741
Query: 986 TKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGGKAMLPIKWMPPE 1043
++HRD+AARN L+ K++DFG+ R D + Y +GGK +PI+W PE
Sbjct: 742 NHNYVHRDLAARNILVNQN---LCCKVSDFGLTRLLDDFDGTYETQGGK--IPIRWTAPE 796
Query: 1044 AYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
A +FTT +DVWSFG+++WEV S G PY +N+EVM+ + G RL P
Sbjct: 797 AIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPP 848
>BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine
kinase protein.
Length = 890
Score = 169 bits (410), Expect = 6e-41
Identities = 89/248 (35%), Positives = 139/248 (56%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D++ + VAVK L ++ +FL EAA
Sbjct: 513 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DSSFVKVAVKMLKADIIASSDIEEFLREAA 570
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 571 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 629
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 630 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 686
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 687 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 746
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 747 GGNRLKQP 754
>AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinase
protein.
Length = 976
Score = 169 bits (410), Expect = 6e-41
Identities = 95/232 (40%), Positives = 129/232 (55%), Gaps = 15/232 (6%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVH 925
+G+G FGEVY+G R S D VA+KTL + S G +FL EA IM +F+H +I+H
Sbjct: 630 IGEGEFGEVYRGTLRLPSQDCKT--VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query: 926 LIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLE 985
L GV R P I+ E + G L FLRE R L L+ + G YL
Sbjct: 688 LEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQLVAMLQGIASGMNYLS 741
Query: 986 TKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGGKAMLPIKWMPPE 1043
++HRD+AARN L+ K++DFG+ R D + Y +GGK +PI+W PE
Sbjct: 742 NHNYVHRDLAARNILVNQN---LCCKVSDFGLTRLLDDFDGTYETQGGK--IPIRWTAPE 796
Query: 1044 AYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
A +FTT +DVWSFG+++WEV S G PY +N+EVM+ + G RL P
Sbjct: 797 AIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPP 848
>AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein.
Length = 976
Score = 169 bits (410), Expect = 6e-41
Identities = 95/232 (40%), Positives = 129/232 (55%), Gaps = 15/232 (6%)
Query: 866 LGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANIVH 925
+G+G FGEVY+G R S D VA+KTL + S G +FL EA IM +F+H +I+H
Sbjct: 630 IGEGEFGEVYRGTLRLPSQDCKT--VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query: 926 LIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRYLE 985
L GV R P I+ E + G L FLRE R L L+ + G YL
Sbjct: 688 LEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQLVAMLQGIASGMNYLS 741
Query: 986 TKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGGKAMLPIKWMPPE 1043
++HRD+AARN L+ K++DFG+ R D + Y +GGK +PI+W PE
Sbjct: 742 NHNYVHRDLAARNILVNQN---LCCKVSDFGLTRLLDDFDGTYETQGGK--IPIRWTAPE 796
Query: 1044 AYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
A +FTT +DVWSFG+++WEV S G PY +N+EVM+ + G RL P
Sbjct: 797 AIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPP 848
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 168 bits (409), Expect = 8e-41
Identities = 97/255 (38%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Query: 843 LPQGIDV-RGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELST 901
+P + + G+ ++ RE + L+K LG G FG V G ++ + VAVK + E S
Sbjct: 399 VPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWK------GQYDVAVKMIKEGS- 451
Query: 902 GQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPER 961
+E +F EA M K +H +V GVC +P +IV E ++ G L N+LR
Sbjct: 452 -MSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRS------H 504
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L LL DVC+G +LE+ +FIHRD+AARNCL+ VK++DFGM R +
Sbjct: 505 GKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDR---DLCVKVSDFGMTRYV 561
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
Y G P+KW PE + +++K+DVW+FG+L+WEVFSLG PY N +
Sbjct: 562 LDDQYVSSVG-TKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQ 620
Query: 1082 VMELVSGGGRLEKPY 1096
V+ VS G RL +P+
Sbjct: 621 VVLKVSQGHRLYRPH 635
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 168 bits (409), Expect = 8e-41
Identities = 91/244 (37%), Positives = 141/244 (57%), Gaps = 18/244 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R S++L+K LG G FGEV++GL+ + + PVAVKTL S +DFL EA
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTT------PVAVKTLKPGSMDP--NDFLREAQ 279
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM H ++ L VC P +I+ EL+ G L+ +L+ + S + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQN-----DTGSKIHLTQQVDM 334
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGG 1031
+ V G YLE++ +IHRD+AARN L+ G + K+ADFG+AR + D Y+
Sbjct: 335 AAQVASGMAYLESRNYIHRDLAARNVLV---GEHNIYKVADFGLARVFKVDNEDIYESRH 391
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+ LP+KW PEA F+ K+DVWSFG+LL+E+ + G MPY+G +V+++++ R
Sbjct: 392 EIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYR 451
Query: 1092 LEKP 1095
L +P
Sbjct: 452 LPQP 455
>U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase
protein.
Length = 882
Score = 168 bits (409), Expect = 8e-41
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D + + VAVK L ++ +FL EAA
Sbjct: 505 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DGSFVKVAVKMLKADIIASSDIEEFLREAA 562
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 563 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 621
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 622 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 678
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 679 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 738
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 739 GGNRLKQP 746
>U05682-1|AAA19236.1| 890|Homo sapiens Rse protein.
Length = 890
Score = 168 bits (409), Expect = 8e-41
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D + + VAVK L ++ +FL EAA
Sbjct: 513 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DGSFVKVAVKMLKADIIASSDIEEFLREAA 570
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 571 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 629
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 630 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 686
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 687 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 746
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 747 GGNRLKQP 754
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 168 bits (409), Expect = 8e-41
Identities = 91/244 (37%), Positives = 141/244 (57%), Gaps = 18/244 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R S++L+K LG G FGEV++GL+ + + PVAVKTL S +DFL EA
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTT------PVAVKTLKPGSMDP--NDFLREAQ 279
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM H ++ L VC P +I+ EL+ G L+ +L+ + S + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQN-----DTGSKIHLTQQVDM 334
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGG 1031
+ V G YLE++ +IHRD+AARN L+ G + K+ADFG+AR + D Y+
Sbjct: 335 AAQVASGMAYLESRNYIHRDLAARNVLV---GEHNIYKVADFGLARVFKVDNEDIYESRH 391
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+ LP+KW PEA F+ K+DVWSFG+LL+E+ + G MPY+G +V+++++ R
Sbjct: 392 EIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYR 451
Query: 1092 LEKP 1095
L +P
Sbjct: 452 LPQP 455
>D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase
protein.
Length = 884
Score = 168 bits (409), Expect = 8e-41
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D + + VAVK L ++ +FL EAA
Sbjct: 507 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DGSFVKVAVKMLKADIIASSDIEEFLREAA 564
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 565 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 623
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 624 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 680
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 681 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 740
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 741 GGNRLKQP 748
>D17517-1|BAA04467.1| 890|Homo sapiens Sky protein.
Length = 890
Score = 168 bits (409), Expect = 8e-41
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D + + VAVK L ++ +FL EAA
Sbjct: 513 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DGSFVKVAVKMLKADIIASSDIEEFLREAA 570
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 571 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 629
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 630 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 686
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 687 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 746
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 747 GGNRLKQP 754
>BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine
kinase protein.
Length = 890
Score = 168 bits (409), Expect = 8e-41
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D + + VAVK L ++ +FL EAA
Sbjct: 513 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DGSFVKVAVKMLKADIIASSDIEEFLREAA 570
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 571 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 629
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 630 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 686
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 687 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 746
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 747 GGNRLKQP 754
>BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein.
Length = 518
Score = 168 bits (409), Expect = 8e-41
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D + + VAVK L ++ +FL EAA
Sbjct: 141 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DGSFVKVAVKMLKADIIASSDIEEFLREAA 198
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 199 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 257
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 258 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 314
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 315 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 374
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 375 GGNRLKQP 382
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 168 bits (409), Expect = 8e-41
Identities = 97/255 (38%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Query: 843 LPQGIDV-RGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELST 901
+P + + G+ ++ RE + L+K LG G FG V G ++ + VAVK + E S
Sbjct: 399 VPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWK------GQYDVAVKMIKEGS- 451
Query: 902 GQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPER 961
+E +F EA M K +H +V GVC +P +IV E ++ G L N+LR
Sbjct: 452 -MSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRS------H 504
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L LL DVC+G +LE+ +FIHRD+AARNCL+ VK++DFGM R +
Sbjct: 505 GKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDR---DLCVKVSDFGMTRYV 561
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
Y G P+KW PE + +++K+DVW+FG+L+WEVFSLG PY N +
Sbjct: 562 LDDQYVSSVG-TKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQ 620
Query: 1082 VMELVSGGGRLEKPY 1096
V+ VS G RL +P+
Sbjct: 621 VVLKVSQGHRLYRPH 635
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase protein.
Length = 505
Score = 168 bits (409), Expect = 8e-41
Identities = 91/244 (37%), Positives = 141/244 (57%), Gaps = 18/244 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R S++L+K LG G FGEV++GL+ + + PVAVKTL S +DFL EA
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTT------PVAVKTLKPGSMDP--NDFLREAQ 279
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM H ++ L VC P +I+ EL+ G L+ +L+ + S + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQN-----DTGSKIHLTQQVDM 334
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGG 1031
+ V G YLE++ +IHRD+AARN L+ G + K+ADFG+AR + D Y+
Sbjct: 335 AAQVASGMAYLESRNYIHRDLAARNVLV---GEHNIYKVADFGLARVFKVDNEDIYESRH 391
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+ LP+KW PEA F+ K+DVWSFG+LL+E+ + G MPY+G +V+++++ R
Sbjct: 392 EIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYR 451
Query: 1092 LEKP 1095
L +P
Sbjct: 452 LPQP 455
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase protein.
Length = 505
Score = 168 bits (409), Expect = 8e-41
Identities = 91/244 (37%), Positives = 141/244 (57%), Gaps = 18/244 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R S++L+K LG G FGEV++GL+ + + PVAVKTL S +DFL EA
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTT------PVAVKTLKPGSMDP--NDFLREAQ 279
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM H ++ L VC P +I+ EL+ G L+ +L+ + S + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQN-----DTGSKIHLTQQVDM 334
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGG 1031
+ V G YLE++ +IHRD+AARN L+ G + K+ADFG+AR + D Y+
Sbjct: 335 AAQVASGMAYLESRNYIHRDLAARNVLV---GEHNIYKVADFGLARVFKVDNEDIYESRH 391
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+ LP+KW PEA F+ K+DVWSFG+LL+E+ + G MPY+G +V+++++ R
Sbjct: 392 EIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYR 451
Query: 1092 LEKP 1095
L +P
Sbjct: 452 LPQP 455
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase protein.
Length = 505
Score = 168 bits (409), Expect = 8e-41
Identities = 91/244 (37%), Positives = 141/244 (57%), Gaps = 18/244 (7%)
Query: 854 QVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAA 913
++ R S++L+K LG G FGEV++GL+ + + PVAVKTL S +DFL EA
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTT------PVAVKTLKPGSMDP--NDFLREAQ 279
Query: 914 IMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLC 973
IM H ++ L VC P +I+ EL+ G L+ +L+ + S + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQN-----DTGSKIHLTQQVDM 334
Query: 974 SVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR--DIYRADYYKKGG 1031
+ V G YLE++ +IHRD+AARN L+ G + K+ADFG+AR + D Y+
Sbjct: 335 AAQVASGMAYLESRNYIHRDLAARNVLV---GEHNIYKVADFGLARVFKVDNEDIYESRH 391
Query: 1032 KAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGR 1091
+ LP+KW PEA F+ K+DVWSFG+LL+E+ + G MPY+G +V+++++ R
Sbjct: 392 EIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYR 451
Query: 1092 LEKP 1095
L +P
Sbjct: 452 LPQP 455
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 168 bits (409), Expect = 8e-41
Identities = 97/255 (38%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Query: 843 LPQGIDV-RGLPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELST 901
+P + + G+ ++ RE + L+K LG G FG V G ++ + VAVK + E S
Sbjct: 421 VPDSVSLANGIWELKREEITLLKELGSGQFGVVQLGKWK------GQYDVAVKMIKEGS- 473
Query: 902 GQAESDFLMEAAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPER 961
+E +F EA M K +H +V GVC +P +IV E ++ G L N+LR
Sbjct: 474 -MSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRS------H 526
Query: 962 ASALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDI 1021
L LL DVC+G +LE+ +FIHRD+AARNCL+ VK++DFGM R +
Sbjct: 527 GKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDR---DLCVKVSDFGMTRYV 583
Query: 1022 YRADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANRE 1081
Y G P+KW PE + +++K+DVW+FG+L+WEVFSLG PY N +
Sbjct: 584 LDDQYVSSVG-TKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQ 642
Query: 1082 VMELVSGGGRLEKPY 1096
V+ VS G RL +P+
Sbjct: 643 VVLKVSQGHRLYRPH 657
>AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine
kinase variant protein.
Length = 951
Score = 168 bits (409), Expect = 8e-41
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 13/248 (5%)
Query: 855 VSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLP-ELSTGQAESDFLMEAA 913
+ + L + LG+G FG V + + D + + VAVK L ++ +FL EAA
Sbjct: 574 IPEQQFTLGRMLGKGEFGSVREAQLKQE--DGSFVKVAVKMLKADIIASSDIEEFLREAA 631
Query: 914 IMAKFNHANIVHLIGVCFDRHPR------FIVLELLAGGDLKNFLRESRPKPERASALTM 967
M +F+H ++ L+GV + ++L + GDL FL SR E L +
Sbjct: 632 CMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIG-ENPFNLPL 690
Query: 968 KDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIYRADYY 1027
+ L+ VD+ G YL ++ FIHRD+AARNC+L V +ADFG++R IY DYY
Sbjct: 691 QTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE---DMTVCVADFGLSRKIYSGDYY 747
Query: 1028 KKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVS 1087
++G + LP+KW+ E+ D ++T ++DVW+FGV +WE+ + G PY G N E+ +
Sbjct: 748 RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLI 807
Query: 1088 GGGRLEKP 1095
GG RL++P
Sbjct: 808 GGNRLKQP 815
>M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor
protein.
Length = 943
Score = 168 bits (408), Expect = 1e-40
Identities = 86/244 (35%), Positives = 137/244 (56%), Gaps = 12/244 (4%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
L ++S +++ ++ LG+ FG+VY+G + VA+KTL + + G +F E
Sbjct: 465 LKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHE 524
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
A + A+ H N+V L+GV P ++ + GDL FL P + S
Sbjct: 525 AMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVK 584
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
AL D + + G YL + +H+D+A RN L+ + VKI+D G+ R++Y
Sbjct: 585 SALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDK---LNVKISDLGLFREVY 641
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
ADYYK G ++LPI+WM PEA + G F+ +D+WS+GV+LWEVFS G+ PY G +N++V
Sbjct: 642 AADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDV 701
Query: 1083 MELV 1086
+E++
Sbjct: 702 VEMI 705
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 168 bits (408), Expect = 1e-40
Identities = 97/235 (41%), Positives = 134/235 (57%), Gaps = 15/235 (6%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
K +G G FGEVY+G+ + S+ E+PVA+KTL T + DFL EA IM +F+H NI
Sbjct: 617 KVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNI 675
Query: 924 VHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRY 983
+ L GV P I+ E + G L FLRE K S L + +L + G +Y
Sbjct: 676 IRLEGVISKYKPMMIITEYMENGALDKFLRE---KDGEFSVLQLVGMLR---GIAAGMKY 729
Query: 984 LETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR---DIYRADYYKKGGKAMLPIKWM 1040
L ++HRD+AARN L+ S V K++DFG++R D A Y GGK +PI+W
Sbjct: 730 LANMNYVHRDLAARNILVNSN---LVCKVSDFGLSRVLEDDPEATYTTSGGK--IPIRWT 784
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
PEA FT+ +DVWSFG+++WEV + G PY +N EVM+ ++ G RL P
Sbjct: 785 APEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTP 839
>BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 168 bits (408), Expect = 1e-40
Identities = 86/244 (35%), Positives = 137/244 (56%), Gaps = 12/244 (4%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
L ++S +++ ++ LG+ FG+VY+G + VA+KTL + + G +F E
Sbjct: 465 LKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHE 524
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
A + A+ H N+V L+GV P ++ + GDL FL P + S
Sbjct: 525 AMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVK 584
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
AL D + + G YL + +H+D+A RN L+ + VKI+D G+ R++Y
Sbjct: 585 SALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDK---LNVKISDLGLFREVY 641
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
ADYYK G ++LPI+WM PEA + G F+ +D+WS+GV+LWEVFS G+ PY G +N++V
Sbjct: 642 AADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDV 701
Query: 1083 MELV 1086
+E++
Sbjct: 702 VEMI 705
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 168 bits (408), Expect = 1e-40
Identities = 97/235 (41%), Positives = 134/235 (57%), Gaps = 15/235 (6%)
Query: 864 KALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLMEAAIMAKFNHANI 923
K +G G FGEVY+G+ + S+ E+PVA+KTL T + DFL EA IM +F+H NI
Sbjct: 617 KVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNI 675
Query: 924 VHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERASALTMKDLLLCSVDVCKGCRY 983
+ L GV P I+ E + G L FLRE K S L + +L + G +Y
Sbjct: 676 IRLEGVISKYKPMMIITEYMENGALDKFLRE---KDGEFSVLQLVGMLR---GIAAGMKY 729
Query: 984 LETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMAR---DIYRADYYKKGGKAMLPIKWM 1040
L ++HRD+AARN L+ S V K++DFG++R D A Y GGK +PI+W
Sbjct: 730 LANMNYVHRDLAARNILVNSN---LVCKVSDFGLSRVLEDDPEATYTTSGGK--IPIRWT 784
Query: 1041 PPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREVMELVSGGGRLEKP 1095
PEA FT+ +DVWSFG+++WEV + G PY +N EVM+ ++ G RL P
Sbjct: 785 APEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTP 839
>AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 168 bits (408), Expect = 1e-40
Identities = 86/244 (35%), Positives = 137/244 (56%), Gaps = 12/244 (4%)
Query: 852 LPQVSRESLKLVKALGQGAFGEVYQGLYRHRSADAAEMPVAVKTLPELSTGQAESDFLME 911
L ++S +++ ++ LG+ FG+VY+G + VA+KTL + + G +F E
Sbjct: 465 LKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHE 524
Query: 912 AAIMAKFNHANIVHLIGVCFDRHPRFIVLELLAGGDLKNFLRESRPKPERAS-------- 963
A + A+ H N+V L+GV P ++ + GDL FL P + S
Sbjct: 525 AMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVK 584
Query: 964 -ALTMKDLLLCSVDVCKGCRYLETKRFIHRDIAARNCLLTSRGPGRVVKIADFGMARDIY 1022
AL D + + G YL + +H+D+A RN L+ + VKI+D G+ R++Y
Sbjct: 585 SALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDK---LNVKISDLGLFREVY 641
Query: 1023 RADYYKKGGKAMLPIKWMPPEAYIDGVFTTKTDVWSFGVLLWEVFSLGVMPYTGCANREV 1082
ADYYK G ++LPI+WM PEA + G F+ +D+WS+GV+LWEVFS G+ PY G +N++V
Sbjct: 642 AADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDV 701
Query: 1083 MELV 1086
+E++
Sbjct: 702 VEMI 705
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.137 0.435
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 174,948,175
Number of Sequences: 224733
Number of extensions: 7889927
Number of successful extensions: 23296
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1076
Number of HSP's successfully gapped in prelim test: 1653
Number of HSP's that attempted gapping in prelim test: 16628
Number of HSP's gapped (non-prelim): 4172
length of query: 1116
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1018
effective length of database: 51,211,004
effective search space: 52132802072
effective search space used: 52132802072
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 70 (32.3 bits)
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