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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000137-TA|BGIBMGA000137-PA|IPR001772|Kinase-associated,
C-terminal
         (313 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q8MVX2 Cluster: Putative serine/threonine protein kinas...   167   4e-40
UniRef50_P27448 Cluster: MAP/microtubule affinity-regulating kin...   159   6e-38
UniRef50_Q9P0L2-3 Cluster: Isoform 3 of Q9P0L2 ; n=3; Homo sapie...   158   2e-37
UniRef50_Q9P0L2 Cluster: Serine/threonine-protein kinase MARK1; ...   158   2e-37
UniRef50_UPI000065EE71 Cluster: MAP/microtubule affinity-regulat...   156   6e-37
UniRef50_Q4SL09 Cluster: Chromosome 17 SCAF14563, whole genome s...   154   3e-36
UniRef50_Q4T2B2 Cluster: Chromosome undetermined SCAF10300, whol...   151   2e-35
UniRef50_UPI0000660272 Cluster: Homolog of Homo sapiens "MAP/mic...   145   1e-33
UniRef50_O08679 Cluster: Serine/threonine-protein kinase MARK2; ...   142   8e-33
UniRef50_Q5BWC8 Cluster: SJCHGC03805 protein; n=1; Schistosoma j...   142   1e-32
UniRef50_A7SZV3 Cluster: Predicted protein; n=1; Nematostella ve...   140   3e-32
UniRef50_UPI000065FCAE Cluster: MAP/microtubule affinity-regulat...   139   7e-32
UniRef50_Q9U1Z0 Cluster: Putative uncharacterized protein; n=3; ...   113   7e-24
UniRef50_Q96L34 Cluster: MAP/microtubule affinity-regulating kin...    86   1e-15
UniRef50_UPI0001555959 Cluster: PREDICTED: similar to MAP/microt...    85   3e-15
UniRef50_Q54DF2 Cluster: Putative uncharacterized protein mrkA; ...    69   1e-10
UniRef50_Q8C1L3 Cluster: ES cells cDNA, RIKEN full-length enrich...    52   1e-05
UniRef50_Q54TA3 Cluster: Putative uncharacterized protein mrkC; ...    51   4e-05
UniRef50_UPI0000E4986D Cluster: PREDICTED: similar to putative p...    50   6e-05
UniRef50_Q5BWY9 Cluster: SJCHGC07655 protein; n=1; Schistosoma j...    49   2e-04
UniRef50_Q54MV2 Cluster: Putative uncharacterized protein mrkB; ...    46   0.001
UniRef50_UPI0000E21E7B Cluster: PREDICTED: maternal embryonic le...    46   0.001
UniRef50_Q14680 Cluster: Maternal embryonic leucine zipper kinas...    46   0.001
UniRef50_Q5BYP3 Cluster: SJCHGC01970 protein; n=2; Schistosoma j...    45   0.002
UniRef50_UPI00005A08EB Cluster: PREDICTED: similar to Serine/thr...    44   0.005
UniRef50_Q6M929 Cluster: Related to serine/threonine-specific pr...    42   0.027
UniRef50_Q7ZU72 Cluster: Maternal embryonic leucine zipper kinas...    41   0.036
UniRef50_A4RL66 Cluster: Putative uncharacterized protein; n=4; ...    33   7.2  
UniRef50_UPI0000F2C940 Cluster: PREDICTED: similar to protein-ty...    33   9.5  
UniRef50_A0E623 Cluster: Chromosome undetermined scaffold_8, who...    33   9.5  
UniRef50_Q8IYZ1 Cluster: FLJ25439 protein; n=1; Homo sapiens|Rep...    33   9.5  
UniRef50_A2QQQ6 Cluster: Function: S. pombe kin1 affects composi...    33   9.5  

>UniRef50_Q8MVX2 Cluster: Putative serine/threonine protein kinase;
           n=3; Haemonchus contortus|Rep: Putative serine/threonine
           protein kinase - Haemonchus contortus (Barber pole worm)
          Length = 966

 Score =  167 bits (405), Expect = 4e-40
 Identities = 74/86 (86%), Positives = 82/86 (95%)

Query: 67  EEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADS 126
           E+++KPR LRFTWSMKTTSS  P+E+M EIRKVLDANNCDYEQRER+L+LCVHGDPNADS
Sbjct: 863 EDEIKPRSLRFTWSMKTTSSLAPDEMMREIRKVLDANNCDYEQRERYLILCVHGDPNADS 922

Query: 127 LVQWEIEVCKLPRLSLNGVRFKRISG 152
           LVQWE+EVCKLPRLSLNGVRFKRISG
Sbjct: 923 LVQWEMEVCKLPRLSLNGVRFKRISG 948


>UniRef50_P27448 Cluster: MAP/microtubule affinity-regulating kinase
           3; n=41; Euteleostomi|Rep: MAP/microtubule
           affinity-regulating kinase 3 - Homo sapiens (Human)
          Length = 776

 Score =  159 bits (387), Expect = 6e-38
 Identities = 71/94 (75%), Positives = 82/94 (87%)

Query: 59  VCCDRQGNEEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCV 118
           V  +++   ++ KPR LRFTWSMKTTSS DP ++M EIRKVLDANNCDYEQRERFLL CV
Sbjct: 665 VSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCV 724

Query: 119 HGDPNADSLVQWEIEVCKLPRLSLNGVRFKRISG 152
           HGD +A++LVQWE+EVCKLPRLSLNGVRFKRISG
Sbjct: 725 HGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISG 758


>UniRef50_Q9P0L2-3 Cluster: Isoform 3 of Q9P0L2 ; n=3; Homo
           sapiens|Rep: Isoform 3 of Q9P0L2 - Homo sapiens (Human)
          Length = 758

 Score =  158 bits (383), Expect = 2e-37
 Identities = 71/82 (86%), Positives = 75/82 (91%)

Query: 71  KPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSLVQW 130
           KPR LRFTWSMKTTSS DPN++M EIRKVLDANNCDYEQ+ERFLL CVHGD   DSLVQW
Sbjct: 659 KPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQW 718

Query: 131 EIEVCKLPRLSLNGVRFKRISG 152
           E+EVCKLPRLSLNGVRFKRISG
Sbjct: 719 EMEVCKLPRLSLNGVRFKRISG 740


>UniRef50_Q9P0L2 Cluster: Serine/threonine-protein kinase MARK1;
           n=73; Euteleostomi|Rep: Serine/threonine-protein kinase
           MARK1 - Homo sapiens (Human)
          Length = 795

 Score =  158 bits (383), Expect = 2e-37
 Identities = 71/82 (86%), Positives = 75/82 (91%)

Query: 71  KPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSLVQW 130
           KPR LRFTWSMKTTSS DPN++M EIRKVLDANNCDYEQ+ERFLL CVHGD   DSLVQW
Sbjct: 696 KPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQW 755

Query: 131 EIEVCKLPRLSLNGVRFKRISG 152
           E+EVCKLPRLSLNGVRFKRISG
Sbjct: 756 EMEVCKLPRLSLNGVRFKRISG 777


>UniRef50_UPI000065EE71 Cluster: MAP/microtubule affinity-regulating
           kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein
           kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein
           kinase p78) (Ser/Thr protein kinase PAR-1) (Protein
           kinase STK10).; n=9; Euteleostomi|Rep: MAP/microtubule
           affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C-
           associated protein kinase 1) (cTAK1) (C-TAK1)
           (Serine/threonine protein kinase p78) (Ser/Thr protein
           kinase PAR-1) (Protein kinase STK10). - Takifugu
           rubripes
          Length = 818

 Score =  156 bits (379), Expect = 6e-37
 Identities = 70/85 (82%), Positives = 78/85 (91%)

Query: 68  EQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSL 127
           ++ KPR LRFTWSMKTTSS +P ++M EIRKVLD NNCDYEQRERFLLLCVHGD +AD+L
Sbjct: 716 KESKPRSLRFTWSMKTTSSMEPQDMMREIRKVLDTNNCDYEQRERFLLLCVHGDGHADNL 775

Query: 128 VQWEIEVCKLPRLSLNGVRFKRISG 152
           VQWE+EVCKLPRLSLNGVRFKRISG
Sbjct: 776 VQWEMEVCKLPRLSLNGVRFKRISG 800


>UniRef50_Q4SL09 Cluster: Chromosome 17 SCAF14563, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 17
           SCAF14563, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 885

 Score =  154 bits (373), Expect = 3e-36
 Identities = 70/91 (76%), Positives = 76/91 (83%)

Query: 62  DRQGNEEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGD 121
           D +      KPR LRFTWSMKTTSS +P E+M EIRKVLDAN+CDYEQRERFLL CVHGD
Sbjct: 777 DSKEEGRDAKPRSLRFTWSMKTTSSMEPTEMMKEIRKVLDANSCDYEQRERFLLFCVHGD 836

Query: 122 PNADSLVQWEIEVCKLPRLSLNGVRFKRISG 152
              D+LVQWE+EVCKLPRLSLNGVRFKRISG
Sbjct: 837 ARQDNLVQWEMEVCKLPRLSLNGVRFKRISG 867


>UniRef50_Q4T2B2 Cluster: Chromosome undetermined SCAF10300, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF10300,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 867

 Score =  151 bits (367), Expect = 2e-35
 Identities = 69/85 (81%), Positives = 75/85 (88%)

Query: 68  EQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSL 127
           ++ KPR LRFTWSMKTTSS +P  +M EIRKVLDANNCDYEQRE FLLLCVHGD +A  L
Sbjct: 765 KESKPRSLRFTWSMKTTSSMEPQHMMREIRKVLDANNCDYEQREHFLLLCVHGDGHAGHL 824

Query: 128 VQWEIEVCKLPRLSLNGVRFKRISG 152
           VQWE+EVCKLPRLSLNGVRFKRISG
Sbjct: 825 VQWEMEVCKLPRLSLNGVRFKRISG 849


>UniRef50_UPI0000660272 Cluster: Homolog of Homo sapiens
           "MAP/microtubule affinity-regulating kinase 2; n=1;
           Takifugu rubripes|Rep: Homolog of Homo sapiens
           "MAP/microtubule affinity-regulating kinase 2 - Takifugu
           rubripes
          Length = 760

 Score =  145 bits (351), Expect = 1e-33
 Identities = 64/86 (74%), Positives = 75/86 (87%)

Query: 67  EEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADS 126
           ++  KPR LRFTWSMKTTSS +P E+M EIRKVLD+N+C+YEQRER++LLCV G+P  D 
Sbjct: 657 KDAAKPRSLRFTWSMKTTSSMEPTEMMREIRKVLDSNSCEYEQRERYMLLCVSGNPAHDD 716

Query: 127 LVQWEIEVCKLPRLSLNGVRFKRISG 152
            VQWE+EVCKLPRLSLNGVRFKRISG
Sbjct: 717 FVQWEMEVCKLPRLSLNGVRFKRISG 742


>UniRef50_O08679 Cluster: Serine/threonine-protein kinase MARK2;
           n=58; Coelomata|Rep: Serine/threonine-protein kinase
           MARK2 - Rattus norvegicus (Rat)
          Length = 722

 Score =  142 bits (345), Expect = 8e-33
 Identities = 65/92 (70%), Positives = 76/92 (82%), Gaps = 1/92 (1%)

Query: 62  DRQGNE-EQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHG 120
           D++  E  + KPR LRFTWSMKTTSS +PNE+M EIRKVLDAN+C  E  ER++LLCVHG
Sbjct: 613 DKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHERYMLLCVHG 672

Query: 121 DPNADSLVQWEIEVCKLPRLSLNGVRFKRISG 152
            P  ++ VQWE+EVCKLPRLSLNGVRFKRISG
Sbjct: 673 TPGHENFVQWEMEVCKLPRLSLNGVRFKRISG 704


>UniRef50_Q5BWC8 Cluster: SJCHGC03805 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC03805 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 316

 Score =  142 bits (343), Expect = 1e-32
 Identities = 62/85 (72%), Positives = 75/85 (88%)

Query: 68  EQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSL 127
           +Q KPR LRFTWSMKTTSS  P+ ++ EI+KVL ANNC+Y+QRER+LL+C +GDP+ D+ 
Sbjct: 214 DQTKPRSLRFTWSMKTTSSMCPDNMIKEIKKVLTANNCEYDQRERYLLICEYGDPSTDAN 273

Query: 128 VQWEIEVCKLPRLSLNGVRFKRISG 152
           VQWE+EVCKLPRLSLNGVRFKRISG
Sbjct: 274 VQWEMEVCKLPRLSLNGVRFKRISG 298


>UniRef50_A7SZV3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 652

 Score =  140 bits (340), Expect = 3e-32
 Identities = 62/84 (73%), Positives = 73/84 (86%)

Query: 71  KPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSLVQW 130
           KPR LRFTWSMKTTS+ DP +++ EI KVL+ANNCDYEQRE++LLLC HG P  ++ VQW
Sbjct: 553 KPRSLRFTWSMKTTSTMDPYDMIREIMKVLEANNCDYEQREKYLLLCCHGSPAENNHVQW 612

Query: 131 EIEVCKLPRLSLNGVRFKRISGQN 154
           E+EVCKLPRLSLNGVRFKRISG +
Sbjct: 613 EMEVCKLPRLSLNGVRFKRISGSS 636


>UniRef50_UPI000065FCAE Cluster: MAP/microtubule affinity-regulating
           kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein
           kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein
           kinase p78) (Ser/Thr protein kinase PAR-1) (Protein
           kinase STK10).; n=1; Takifugu rubripes|Rep:
           MAP/microtubule affinity-regulating kinase 3 (EC
           2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1)
           (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr
           protein kinase PAR-1) (Protein kinase STK10). - Takifugu
           rubripes
          Length = 757

 Score =  139 bits (337), Expect = 7e-32
 Identities = 62/83 (74%), Positives = 72/83 (86%)

Query: 62  DRQGNEEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGD 121
           D++G  +  KPR LRFTWSM+TTSS +P +IM EIRKVLDANNCDYEQ+E FLLLCVHGD
Sbjct: 675 DQKGESKDGKPRSLRFTWSMRTTSSMEPCDIMREIRKVLDANNCDYEQQESFLLLCVHGD 734

Query: 122 PNADSLVQWEIEVCKLPRLSLNG 144
             A++LVQWE+EVCKLPRLSLNG
Sbjct: 735 GRAENLVQWEMEVCKLPRLSLNG 757


>UniRef50_Q9U1Z0 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 142

 Score =  113 bits (271), Expect = 7e-24
 Identities = 50/88 (56%), Positives = 67/88 (76%)

Query: 67  EEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADS 126
           +++  PR +RFTW++K TS  +P+EI+ EI+KVL +   DYEQ++RFLL C H DP  D+
Sbjct: 39  DQEDMPRAVRFTWNLKKTSMLEPDEILKEIQKVLGSYGIDYEQQKRFLLRCSHVDPLTDA 98

Query: 127 LVQWEIEVCKLPRLSLNGVRFKRISGQN 154
            V+WEIEVC LPRL LNGV F+RISG +
Sbjct: 99  SVKWEIEVCTLPRLYLNGVHFQRISGSS 126


>UniRef50_Q96L34 Cluster: MAP/microtubule affinity-regulating kinase
           4; n=19; Euteleostomi|Rep: MAP/microtubule
           affinity-regulating kinase 4 - Homo sapiens (Human)
          Length = 752

 Score = 86.2 bits (204), Expect = 1e-15
 Identities = 40/93 (43%), Positives = 57/93 (61%), Gaps = 1/93 (1%)

Query: 61  CDRQGNEEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHG 120
           C    ++ +  PR+LRF WS+K TSSR P  +MA +R+   A  C   Q + FLL C+HG
Sbjct: 642 CHLPWDQTETAPRLLRFPWSVKLTSSRPPEALMAALRQATAAARCRCRQPQPFLLACLHG 701

Query: 121 DPNA-DSLVQWEIEVCKLPRLSLNGVRFKRISG 152
                + L  +E+EVC+LPR  L GV F+R++G
Sbjct: 702 GAGGPEPLSHFEVEVCQLPRPGLRGVLFRRVAG 734


>UniRef50_UPI0001555959 Cluster: PREDICTED: similar to
           MAP/microtubule affinity-regulating kinase 4, partial;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           MAP/microtubule affinity-regulating kinase 4, partial -
           Ornithorhynchus anatinus
          Length = 228

 Score = 84.6 bits (200), Expect = 3e-15
 Identities = 39/82 (47%), Positives = 52/82 (63%), Gaps = 1/82 (1%)

Query: 72  PRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNA-DSLVQW 130
           PR+LRF WS+K TSSR P  +MA + +   A  C   Q + FLL C+HG     D L  +
Sbjct: 129 PRLLRFPWSVKLTSSRPPEALMAALHRATHAARCRCRQPQPFLLSCLHGGAGGPDPLSHF 188

Query: 131 EIEVCKLPRLSLNGVRFKRISG 152
           E+EVC+LPR  L GV F+R++G
Sbjct: 189 EVEVCQLPRAGLRGVLFRRVAG 210


>UniRef50_Q54DF2 Cluster: Putative uncharacterized protein mrkA; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein mrkA - Dictyostelium discoideum
            AX4
          Length = 1060

 Score = 69.3 bits (162), Expect = 1e-10
 Identities = 32/88 (36%), Positives = 57/88 (64%), Gaps = 6/88 (6%)

Query: 67   EEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADS 126
            ++Q +PR++RF + + TT+ +D  E+M ++ KV+D     + ++  FL+ C         
Sbjct: 960  QQQQEPRIVRFVFGVNTTTMKDAPELMQQVLKVVDTFCIPHTKKAPFLIEC------ETE 1013

Query: 127  LVQWEIEVCKLPRLSLNGVRFKRISGQN 154
             V++ IE+C+LPRLS+NG++FKRI G +
Sbjct: 1014 GVRFSIEICRLPRLSVNGLKFKRIGGSS 1041


>UniRef50_Q8C1L3 Cluster: ES cells cDNA, RIKEN full-length enriched
           library, clone:2410090P21 product:SIMILAR TO
           MAP/MICROTUBULE AFFINITY-REGULATING KINASE LIKE 1
           homolog; n=1; Mus musculus|Rep: ES cells cDNA, RIKEN
           full-length enriched library, clone:2410090P21
           product:SIMILAR TO MAP/MICROTUBULE AFFINITY-REGULATING
           KINASE LIKE 1 homolog - Mus musculus (Mouse)
          Length = 125

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 25/60 (41%), Positives = 36/60 (60%), Gaps = 1/60 (1%)

Query: 93  MAEIRKVLDANNCDYEQRERFLLLCVHGDPNA-DSLVQWEIEVCKLPRLSLNGVRFKRIS 151
           MA +R+   A  C   Q + FLL C+HG     + L  +E+EVC+LPR  L GV F+R++
Sbjct: 1   MAALRQATAAARCRCRQPQPFLLACLHGGAGGPEPLSHFEVEVCQLPRPGLRGVLFRRVA 60


>UniRef50_Q54TA3 Cluster: Putative uncharacterized protein mrkC;
           n=1; Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein mrkC - Dictyostelium discoideum
           AX4
          Length = 773

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 23/87 (26%), Positives = 50/87 (57%), Gaps = 4/87 (4%)

Query: 66  NEEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNAD 125
           N+    PR  +  +   TT+++ P + + E+++ L+ +    +++  +L LC     + D
Sbjct: 673 NQHMASPRTSKGIFKSSTTTTKSPEKTIIELKRSLEESGLFTKKKGPYLFLCF----DED 728

Query: 126 SLVQWEIEVCKLPRLSLNGVRFKRISG 152
           + V+++IE+ K+  L L G++ KR+SG
Sbjct: 729 NSVKFQIEIVKICNLDLTGIQLKRLSG 755


>UniRef50_UPI0000E4986D Cluster: PREDICTED: similar to putative
           protein serine/threonine kinase; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to putative protein
           serine/threonine kinase - Strongylocentrotus purpuratus
          Length = 141

 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 29/84 (34%), Positives = 47/84 (55%), Gaps = 9/84 (10%)

Query: 71  KPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCD--YEQRERFLLLCVHGDPNADSLV 128
           +P  ++   S   T+ +D NEI+ EIR+ LD    D  Y   E    L  +G       V
Sbjct: 47  EPSPIKHAKSFSMTTCKDLNEIVNEIRRTLDRRQPDLVYTNNENMFELQQYG-------V 99

Query: 129 QWEIEVCKLPRLSLNGVRFKRISG 152
           + E+EVC++P L+LNG++ ++I+G
Sbjct: 100 EMEMEVCRVPGLALNGLKLRKIAG 123


>UniRef50_Q5BWY9 Cluster: SJCHGC07655 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC07655 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 247

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 23/53 (43%), Positives = 33/53 (62%)

Query: 71  KPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPN 123
           + R LRF +  +T S R   E+M +I++VL  NN D+EQ     L CV+GDP+
Sbjct: 151 RTRSLRFMFRTETASRRQIEEMMLDIKQVLTKNNVDFEQVGDLKLQCVYGDPS 203


>UniRef50_Q54MV2 Cluster: Putative uncharacterized protein mrkB;
           n=1; Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein mrkB - Dictyostelium discoideum
           AX4
          Length = 715

 Score = 46.4 bits (105), Expect = 0.001
 Identities = 27/102 (26%), Positives = 55/102 (53%), Gaps = 3/102 (2%)

Query: 63  RQGNEEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDP 122
           R G  +  K R ++  ++  TT+  +P +++  I + L++    Y +R  ++  C    P
Sbjct: 610 RSGKGKNPKIRSMKGPFNSGTTTMLNPIQLIEHIEENLNSTQISY-RRNFYVFDCKTLCP 668

Query: 123 NADSLVQWEIEVCKLPRLSLNGVRFKRISGQNKHRLQEHCVK 164
             ++ + +EIEVCK+  + + G++FKR+SG +       C+K
Sbjct: 669 RNET-INFEIEVCKVNGMDMYGIKFKRLSG-DAWSYSSSCIK 708


>UniRef50_UPI0000E21E7B Cluster: PREDICTED: maternal embryonic
           leucine zipper kinase isoform 12; n=3; Eutheria|Rep:
           PREDICTED: maternal embryonic leucine zipper kinase
           isoform 12 - Pan troglodytes
          Length = 622

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 1/81 (1%)

Query: 72  PRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSLVQWE 131
           PR L+  +++ TT   +P++++ EI  +L   + D+ Q+  + L C          +Q+E
Sbjct: 525 PRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKG-YTLKCQTQSDFGKVTMQFE 583

Query: 132 IEVCKLPRLSLNGVRFKRISG 152
           +EVC+L +  + G+R +R+ G
Sbjct: 584 LEVCQLQKPDVVGIRRQRLKG 604


>UniRef50_Q14680 Cluster: Maternal embryonic leucine zipper kinase;
           n=37; Tetrapoda|Rep: Maternal embryonic leucine zipper
           kinase - Homo sapiens (Human)
          Length = 651

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 1/81 (1%)

Query: 72  PRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSLVQWE 131
           PR L+  +++ TT   +P++++ EI  +L   + D+ Q+  + L C          +Q+E
Sbjct: 554 PRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKG-YTLKCQTQSDFGKVTMQFE 612

Query: 132 IEVCKLPRLSLNGVRFKRISG 152
           +EVC+L +  + G+R +R+ G
Sbjct: 613 LEVCQLQKPDVVGIRRQRLKG 633


>UniRef50_Q5BYP3 Cluster: SJCHGC01970 protein; n=2; Schistosoma
           japonicum|Rep: SJCHGC01970 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 509

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 20/38 (52%), Positives = 23/38 (60%)

Query: 119 HGDPNADSLVQWEIEVCKLPRLSLNGVRFKRISGQNKH 156
           HG       V WE+EVC+LPR+ L GVR KRI G   H
Sbjct: 458 HGGLLRGDPVHWEMEVCQLPRVHLRGVRLKRIRGSTLH 495



 Score = 37.1 bits (82), Expect = 0.58
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 3/59 (5%)

Query: 62  DRQGNEEQVKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDAN-NCDYEQRER--FLLLC 117
           D Q +    KPR ++F WSM TTS++   E++  I   L+    C Y       FLL C
Sbjct: 365 DNQSSRLLNKPREVKFPWSMYTTSTKSAEELLKSIIYTLEVTPGCRYSHDPHLPFLLQC 423


>UniRef50_UPI00005A08EB Cluster: PREDICTED: similar to
           Serine/threonine-protein kinase MARK2 (MAP/microtubule
           affinity-regulating kinase 2) (ELKL motif kinase) (EMK1)
           (PAR1 homolog); n=1; Canis lupus familiaris|Rep:
           PREDICTED: similar to Serine/threonine-protein kinase
           MARK2 (MAP/microtubule affinity-regulating kinase 2)
           (ELKL motif kinase) (EMK1) (PAR1 homolog) - Canis
           familiaris
          Length = 206

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 17/56 (30%), Positives = 30/56 (53%)

Query: 81  MKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSLVQWEIEVCK 136
           M   +S +PN++M E  KVLD N+C Y+  +++           D  +QW++ + K
Sbjct: 1   MTIANSMEPNKMMREFSKVLDTNSCQYKLNKKWCCCACKAPQGQDDFLQWKLAIDK 56


>UniRef50_Q6M929 Cluster: Related to serine/threonine-specific
           protein kinase KIN1; n=3; Sordariaceae|Rep: Related to
           serine/threonine-specific protein kinase KIN1 -
           Neurospora crassa
          Length = 880

 Score = 41.5 bits (93), Expect = 0.027
 Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 11/94 (11%)

Query: 70  VKPRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRE-----RFLLLCVHGD--- 121
           VKP  L+  +S+ TTS++  +EI A+I++VL     ++ + +     R      H +   
Sbjct: 769 VKPVFLKGIFSVSTTSTKPLSEIRADIKRVLRVLGVEFNEIKGGFSCRHTPSINHAERQP 828

Query: 122 ---PNADSLVQWEIEVCKLPRLSLNGVRFKRISG 152
                  + +++EI + K+P +SL+GV+FKR++G
Sbjct: 829 TVMTEGGNEIEFEILIVKVPIVSLHGVQFKRLAG 862


>UniRef50_Q7ZU72 Cluster: Maternal embryonic leucine zipper kinase;
           n=7; Euteleostomi|Rep: Maternal embryonic leucine zipper
           kinase - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 676

 Score = 41.1 bits (92), Expect = 0.036
 Identities = 20/81 (24%), Positives = 44/81 (54%), Gaps = 1/81 (1%)

Query: 72  PRVLRFTWSMKTTSSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSLVQWE 131
           PR ++  +++  T+  + ++++ +I  +L   N D+ Q+  + L C          +Q+E
Sbjct: 576 PRKIKAQYNVTLTNQTNADQVLNQILSILPEKNVDFVQKG-YTLKCHTQSDFGKVTMQFE 634

Query: 132 IEVCKLPRLSLNGVRFKRISG 152
           +EVC L +  + G+R +R+ G
Sbjct: 635 LEVCLLQKPEVVGIRRQRLKG 655


>UniRef50_A4RL66 Cluster: Putative uncharacterized protein; n=4;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 992

 Score = 33.5 bits (73), Expect = 7.2
 Identities = 13/35 (37%), Positives = 23/35 (65%)

Query: 118 VHGDPNADSLVQWEIEVCKLPRLSLNGVRFKRISG 152
           V  D     + ++EI + K+P +SL+G++FKR+ G
Sbjct: 940 VRSDMGESMVSEFEIFIVKVPMISLHGIQFKRLGG 974


>UniRef50_UPI0000F2C940 Cluster: PREDICTED: similar to
           protein-tyrosine phosphatase; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to protein-tyrosine
           phosphatase - Monodelphis domestica
          Length = 703

 Score = 33.1 bits (72), Expect = 9.5
 Identities = 15/27 (55%), Positives = 18/27 (66%)

Query: 287 APTAPRPLAPHTPVTVRLSAPRADPPS 313
           AP+AP PL   TP +V LS P A PP+
Sbjct: 344 APSAPAPLPALTPFSVSLSLPPARPPA 370


>UniRef50_A0E623 Cluster: Chromosome undetermined scaffold_8, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_8,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 1323

 Score = 33.1 bits (72), Expect = 9.5
 Identities = 17/80 (21%), Positives = 41/80 (51%)

Query: 85  SSRDPNEIMAEIRKVLDANNCDYEQRERFLLLCVHGDPNADSLVQWEIEVCKLPRLSLNG 144
           S+   N+I+ +++  +   NC+ + +++ +L+ +    N + +++ +I   + P + L G
Sbjct: 861 SNSQANQIIKQMQDKISEWNCNSQLQQKSILIYLMSFINKEDILKEKILEQRKPSIRLEG 920

Query: 145 VRFKRISGQNKHRLQEHCVK 164
           +    I  QNK  L +   K
Sbjct: 921 ILTSNIDCQNKQELVQSSQK 940


>UniRef50_Q8IYZ1 Cluster: FLJ25439 protein; n=1; Homo sapiens|Rep:
          FLJ25439 protein - Homo sapiens (Human)
          Length = 143

 Score = 33.1 bits (72), Expect = 9.5
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 31 AAIHRTLRPKRC-PLPQYSRLIIMLPL---KPVCCDRQGNEEQVKPRVLRFTWSMKTTSS 86
          A + R  R +RC P P  S+L+ M        +C   Q  +     +    TW   TTS+
Sbjct: 23 APLWRPDRGRRCKPAPSVSQLLAMTSTGISASICLPVQAKKHATSAKNTLLTWKANTTSN 82

Query: 87 RDPNEIMAEIRKV 99
          ++  EI+  + K+
Sbjct: 83 KEKEEILEALVKL 95


>UniRef50_A2QQQ6 Cluster: Function: S. pombe kin1 affects composition
            or organization of the cell wall; n=9;
            Eurotiomycetidae|Rep: Function: S. pombe kin1 affects
            composition or organization of the cell wall -
            Aspergillus niger
          Length = 1075

 Score = 33.1 bits (72), Expect = 9.5
 Identities = 12/35 (34%), Positives = 25/35 (71%)

Query: 118  VHGDPNADSLVQWEIEVCKLPRLSLNGVRFKRISG 152
            V  D   + ++++EI + K+P  SL+G++FK+++G
Sbjct: 1023 VQSDTGENLVLRFEILIVKVPLFSLHGIQFKKVAG 1057


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.320    0.134    0.413 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 275,093,760
Number of Sequences: 1657284
Number of extensions: 9272690
Number of successful extensions: 23440
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 23404
Number of HSP's gapped (non-prelim): 36
length of query: 313
length of database: 575,637,011
effective HSP length: 101
effective length of query: 212
effective length of database: 408,251,327
effective search space: 86549281324
effective search space used: 86549281324
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 72 (33.1 bits)

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