Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000136-TA|BGIBMGA000136-PA|IPR011009|Protein
kinase-like, IPR000449|Ubiquitin-associated, IPR000719|Protein kinase,
IPR008271|Serine/threonine protein kinase, active site,
IPR002290|Serine/threonine protein kinase
(652 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 576 e-163
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 576 e-163
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 576 e-163
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 574 e-163
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 573 e-163
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 570 e-162
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 570 e-162
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 570 e-162
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 570 e-162
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 570 e-162
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 570 e-162
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 568 e-161
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 568 e-161
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 568 e-161
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 568 e-161
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 562 e-159
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 562 e-159
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 562 e-159
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 562 e-159
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 559 e-158
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 559 e-158
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 552 e-156
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 505 e-142
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 505 e-142
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 470 e-132
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 423 e-118
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 418 e-116
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 398 e-110
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 393 e-109
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 365 e-100
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 365 e-100
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 365 e-100
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 365 e-100
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 355 4e-97
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 355 4e-97
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 355 4e-97
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 349 2e-95
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 284 6e-76
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 284 6e-76
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 284 6e-76
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 284 6e-76
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 277 7e-74
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 276 2e-73
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 276 2e-73
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 276 2e-73
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 276 2e-73
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 276 2e-73
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 276 2e-73
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 275 3e-73
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 273 1e-72
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 270 1e-71
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 266 1e-70
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 266 1e-70
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 266 1e-70
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 266 1e-70
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 266 1e-70
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 265 3e-70
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 264 5e-70
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 264 7e-70
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 264 7e-70
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 262 3e-69
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 261 5e-69
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 261 5e-69
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 259 2e-68
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 257 8e-68
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 251 5e-66
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 251 5e-66
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 251 5e-66
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 251 5e-66
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 251 5e-66
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 248 4e-65
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 248 5e-65
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 240 1e-62
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 226 2e-58
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 216 2e-55
BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein. 207 1e-52
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 202 4e-51
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 198 4e-50
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 198 4e-50
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 198 4e-50
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 198 4e-50
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 195 5e-49
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 192 4e-48
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 192 4e-48
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 192 4e-48
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 186 2e-46
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 186 2e-46
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 185 5e-46
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 185 5e-46
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 185 5e-46
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 185 5e-46
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 185 5e-46
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 183 2e-45
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 183 2e-45
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 180 1e-44
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 179 2e-44
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 179 2e-44
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 179 2e-44
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 179 2e-44
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 179 2e-44
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 179 2e-44
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 179 2e-44
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 179 2e-44
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 179 2e-44
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 179 2e-44
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 179 2e-44
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 179 2e-44
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 179 2e-44
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 179 2e-44
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 179 2e-44
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 179 2e-44
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 178 4e-44
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 178 6e-44
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 177 8e-44
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 175 3e-43
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 175 3e-43
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 175 4e-43
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 174 7e-43
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 174 7e-43
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 174 7e-43
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 174 7e-43
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 173 2e-42
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 173 2e-42
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 173 2e-42
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 173 2e-42
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 173 2e-42
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 173 2e-42
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 172 3e-42
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 172 3e-42
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 172 3e-42
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 172 3e-42
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 172 3e-42
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 172 3e-42
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 172 3e-42
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 172 3e-42
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 172 3e-42
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 172 3e-42
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 172 4e-42
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 172 4e-42
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 172 4e-42
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 172 4e-42
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 172 4e-42
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 172 4e-42
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 171 5e-42
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 171 5e-42
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 171 5e-42
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 171 5e-42
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 171 5e-42
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 171 5e-42
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 171 5e-42
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 171 5e-42
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 171 5e-42
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 171 5e-42
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 171 5e-42
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 171 7e-42
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 171 7e-42
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 171 7e-42
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 171 7e-42
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 171 7e-42
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 171 9e-42
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 171 9e-42
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 171 9e-42
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 171 9e-42
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 171 9e-42
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 171 9e-42
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 171 9e-42
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 171 9e-42
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 171 9e-42
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 170 1e-41
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 170 1e-41
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 170 2e-41
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 170 2e-41
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 170 2e-41
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 170 2e-41
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 170 2e-41
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 170 2e-41
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 170 2e-41
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 170 2e-41
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 170 2e-41
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 170 2e-41
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 170 2e-41
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 170 2e-41
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 170 2e-41
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 170 2e-41
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 170 2e-41
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 170 2e-41
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 170 2e-41
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 170 2e-41
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 168 5e-41
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 168 5e-41
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 167 8e-41
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 167 8e-41
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 167 8e-41
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 167 8e-41
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 167 8e-41
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 167 1e-40
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 167 1e-40
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 167 1e-40
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 167 1e-40
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 167 1e-40
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 167 1e-40
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 167 1e-40
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 167 1e-40
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 167 1e-40
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 167 1e-40
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 167 1e-40
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 167 1e-40
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 166 2e-40
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 166 2e-40
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 166 2e-40
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 166 2e-40
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 166 2e-40
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 166 2e-40
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 166 2e-40
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 166 2e-40
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 166 2e-40
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 166 2e-40
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 166 2e-40
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 165 3e-40
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 165 4e-40
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 165 4e-40
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 165 4e-40
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 165 4e-40
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 165 4e-40
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 165 4e-40
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 165 4e-40
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 165 4e-40
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 165 4e-40
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 165 4e-40
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 165 4e-40
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 165 4e-40
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 165 6e-40
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 165 6e-40
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 165 6e-40
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 165 6e-40
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 165 6e-40
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 165 6e-40
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 165 6e-40
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 165 6e-40
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 165 6e-40
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 165 6e-40
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 165 6e-40
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 165 6e-40
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 165 6e-40
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 165 6e-40
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 165 6e-40
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 165 6e-40
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 165 6e-40
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 164 8e-40
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 164 1e-39
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 164 1e-39
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 164 1e-39
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 163 1e-39
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 163 1e-39
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 163 2e-39
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 163 2e-39
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 163 2e-39
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 163 2e-39
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 163 2e-39
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 163 2e-39
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 163 2e-39
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 163 2e-39
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 163 2e-39
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 163 2e-39
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 162 3e-39
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 162 4e-39
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 162 4e-39
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 162 4e-39
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 162 4e-39
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 162 4e-39
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 161 5e-39
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 161 5e-39
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 161 7e-39
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 161 7e-39
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 161 7e-39
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 161 7e-39
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 161 7e-39
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 161 9e-39
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 161 9e-39
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 161 9e-39
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 161 9e-39
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 161 9e-39
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 161 9e-39
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 161 9e-39
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 161 9e-39
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 161 9e-39
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 161 9e-39
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 161 9e-39
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 161 9e-39
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 160 1e-38
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 160 1e-38
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 160 1e-38
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 160 1e-38
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 160 2e-38
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 159 2e-38
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 159 2e-38
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 159 2e-38
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 159 2e-38
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 159 2e-38
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 159 3e-38
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 159 3e-38
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 159 3e-38
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 159 3e-38
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 159 3e-38
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 159 3e-38
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 159 4e-38
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 159 4e-38
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 159 4e-38
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 159 4e-38
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 159 4e-38
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 159 4e-38
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 159 4e-38
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 159 4e-38
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 158 5e-38
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 158 5e-38
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 158 5e-38
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 158 5e-38
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 158 5e-38
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 158 5e-38
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 158 5e-38
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 158 5e-38
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 158 5e-38
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 158 5e-38
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 158 5e-38
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 158 5e-38
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 158 7e-38
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 158 7e-38
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 158 7e-38
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 157 9e-38
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 157 9e-38
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 157 9e-38
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 157 1e-37
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 157 1e-37
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 157 1e-37
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 157 1e-37
BC071948-1|AAH71948.1| 97|Homo sapiens MARK4 protein protein. 157 2e-37
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 157 2e-37
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 155 3e-37
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 155 3e-37
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 155 3e-37
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 155 3e-37
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 155 3e-37
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 155 5e-37
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 155 5e-37
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 155 5e-37
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 155 5e-37
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 155 5e-37
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 155 6e-37
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 154 8e-37
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 154 8e-37
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 154 8e-37
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 154 8e-37
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 154 8e-37
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 154 8e-37
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 154 8e-37
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 154 8e-37
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 154 8e-37
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 154 8e-37
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 154 8e-37
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 154 8e-37
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 154 8e-37
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 154 8e-37
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 154 8e-37
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 154 8e-37
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 153 1e-36
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 153 1e-36
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 153 2e-36
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 153 2e-36
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 153 2e-36
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 153 2e-36
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 153 2e-36
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 153 2e-36
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 153 2e-36
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 152 3e-36
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 152 3e-36
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 152 3e-36
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 152 3e-36
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 152 3e-36
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 152 3e-36
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 152 3e-36
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 152 3e-36
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 152 3e-36
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 152 3e-36
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 152 3e-36
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 152 3e-36
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 152 3e-36
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 152 3e-36
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 152 3e-36
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 152 3e-36
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 152 3e-36
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 152 3e-36
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 152 3e-36
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 152 3e-36
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 152 4e-36
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 152 4e-36
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 152 4e-36
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 152 4e-36
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 152 4e-36
Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 151 6e-36
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 151 6e-36
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 151 6e-36
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 151 6e-36
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 151 6e-36
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 151 6e-36
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 151 6e-36
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 151 6e-36
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 151 6e-36
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 151 1e-35
BC117311-1|AAI17312.1| 898|Homo sapiens CASK protein protein. 151 1e-35
AY705392-1|AAU10527.1| 921|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL627402-6|CAH71241.1| 590|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL627402-5|CAH71238.1| 897|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL627402-4|CAH71237.1| 909|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL627402-3|CAH71240.1| 926|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL627402-2|CAH71239.1| 921|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL603754-6|CAI41638.1| 590|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL603754-5|CAI41635.1| 926|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL603754-4|CAI41636.1| 921|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL603754-3|CAI41637.1| 897|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL603754-2|CAI41634.1| 909|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL445239-7|CAI41096.1| 590|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL445239-6|CAI41093.1| 926|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL445239-5|CAI41094.1| 921|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL445239-4|CAI41095.1| 897|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL445239-3|CAI41092.1| 909|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL353691-7|CAI42248.1| 590|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL353691-6|CAI42245.1| 926|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL353691-5|CAI42246.1| 921|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL353691-4|CAI42247.1| 897|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL353691-3|CAI42244.1| 909|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL158144-5|CAI42766.1| 590|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL158144-4|CAI42763.1| 926|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL158144-3|CAI42764.1| 921|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL158144-2|CAI42765.1| 897|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AL158144-1|CAI42762.1| 909|Homo sapiens calcium/calmodulin-depe... 151 1e-35
AF035582-1|AAB88198.1| 897|Homo sapiens CASK protein. 151 1e-35
AF032119-1|AAB88125.1| 921|Homo sapiens hCASK protein. 151 1e-35
AB208859-1|BAD92096.1| 917|Homo sapiens calcium/calmodulin-depe... 151 1e-35
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 150 1e-35
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 150 1e-35
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 150 1e-35
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 150 1e-35
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 149 4e-35
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 149 4e-35
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 149 4e-35
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 149 4e-35
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 148 5e-35
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 148 5e-35
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 148 5e-35
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 148 5e-35
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 148 5e-35
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 148 5e-35
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 148 5e-35
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 148 7e-35
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 148 7e-35
BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for IM... 148 7e-35
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 148 7e-35
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 148 7e-35
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 148 7e-35
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 147 9e-35
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 147 9e-35
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 147 9e-35
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 147 9e-35
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 147 9e-35
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 147 9e-35
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 147 1e-34
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 147 1e-34
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 147 1e-34
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 147 1e-34
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 146 2e-34
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 146 2e-34
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 146 2e-34
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 146 2e-34
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 145 4e-34
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 145 4e-34
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 145 4e-34
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 145 4e-34
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 145 4e-34
AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 145 4e-34
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 145 4e-34
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 145 5e-34
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 145 5e-34
BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for IM... 145 5e-34
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 145 5e-34
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 145 5e-34
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 144 9e-34
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 144 9e-34
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 144 9e-34
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 144 9e-34
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 144 9e-34
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 144 9e-34
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 144 9e-34
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 576 bits (1421), Expect = e-163
Identities = 264/320 (82%), Positives = 298/320 (93%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 51 PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYL+MEYASGGEVFDYLV HGRMKEKEAR+KFRQIVSAVQYCH
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QKRI+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYD 230
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLK+FLVL
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVL 290
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR +LE IM+D+W+N G+EEDEL+P+VEP+ D D KRI+ +V +GY+++EI+ SL+
Sbjct: 291 NPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLS 350
Query: 335 EAKYDDVFATYLLLGRKSTD 354
+ KYD++ ATYLLLGRKS++
Sbjct: 351 KMKYDEITATYLLLGRKSSE 370
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 576 bits (1421), Expect = e-163
Identities = 264/320 (82%), Positives = 298/320 (93%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 51 PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYL+MEYASGGEVFDYLV HGRMKEKEAR+KFRQIVSAVQYCH
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QKRI+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYD 230
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLK+FLVL
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVL 290
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR +LE IM+D+W+N G+EEDEL+P+VEP+ D D KRI+ +V +GY+++EI+ SL+
Sbjct: 291 NPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLS 350
Query: 335 EAKYDDVFATYLLLGRKSTD 354
+ KYD++ ATYLLLGRKS++
Sbjct: 351 KMKYDEITATYLLLGRKSSE 370
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 576 bits (1421), Expect = e-163
Identities = 264/320 (82%), Positives = 298/320 (93%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 51 PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYL+MEYASGGEVFDYLV HGRMKEKEAR+KFRQIVSAVQYCH
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QKRI+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYD 230
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLK+FLVL
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVL 290
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR +LE IM+D+W+N G+EEDEL+P+VEP+ D D KRI+ +V +GY+++EI+ SL+
Sbjct: 291 NPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLS 350
Query: 335 EAKYDDVFATYLLLGRKSTD 354
+ KYD++ ATYLLLGRKS++
Sbjct: 351 KMKYDEITATYLLLGRKSSE 370
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 574 bits (1417), Expect = e-163
Identities = 263/320 (82%), Positives = 298/320 (93%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 51 PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYL+MEYASGG+VFDYLV HGRMKEKEAR+KFRQIVSAVQYCH
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QKRI+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYD 230
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLK+FLVL
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVL 290
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR +LE IM+D+W+N G+EEDEL+P+VEP+ D D KRI+ +V +GY+++EI+ SL+
Sbjct: 291 NPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLS 350
Query: 335 EAKYDDVFATYLLLGRKSTD 354
+ KYD++ ATYLLLGRKS++
Sbjct: 351 KMKYDEITATYLLLGRKSSE 370
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 573 bits (1414), Expect = e-163
Identities = 262/320 (81%), Positives = 298/320 (93%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 51 PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIET+KTLYL+MEYASGG+VFDYLV HGRMKEKEAR+KFRQIVSAVQYCH
Sbjct: 111 NHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QKRI+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYD 230
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLK+FLVL
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVL 290
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR +LE IM+D+W+N G+EEDEL+P+VEP+ D D KRI+ +V +GY+++EI+ SL+
Sbjct: 291 NPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLS 350
Query: 335 EAKYDDVFATYLLLGRKSTD 354
+ KYD++ ATYLLLGRKS++
Sbjct: 351 KMKYDEITATYLLLGRKSSE 370
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 570 bits (1406), Expect = e-162
Identities = 265/322 (82%), Positives = 294/322 (91%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TGKEVA+KIIDKTQLN SLQKLFREVRIMK+L
Sbjct: 15 PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 74
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKKFL+L
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 254
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP+KR +LE IM+D+WMN G+E+DEL+PYVEP D+KD +R E +V +GY R+EI+ SL
Sbjct: 255 NPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLV 314
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
+Y++V ATYLLLG KS++ E
Sbjct: 315 GQRYNEVMATYLLLGYKSSELE 336
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/22 (63%), Positives = 17/22 (77%)
Query: 572 PNQLVFPRNVPSRSTFHSGQTR 593
P++ FPR V SRSTFH+GQ R
Sbjct: 548 PDRTNFPRGVSSRSTFHAGQLR 569
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 570 bits (1406), Expect = e-162
Identities = 265/322 (82%), Positives = 294/322 (91%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TGKEVA+KIIDKTQLN SLQKLFREVRIMK+L
Sbjct: 15 PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 74
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKKFL+L
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 254
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP+KR +LE IM+D+WMN G+E+DEL+PYVEP D+KD +R E +V +GY R+EI+ SL
Sbjct: 255 NPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLV 314
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
+Y++V ATYLLLG KS++ E
Sbjct: 315 GQRYNEVMATYLLLGYKSSELE 336
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/22 (63%), Positives = 17/22 (77%)
Query: 572 PNQLVFPRNVPSRSTFHSGQTR 593
P++ FPR V SRSTFH+GQ R
Sbjct: 549 PDRTNFPRGVSSRSTFHAGQLR 570
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 570 bits (1406), Expect = e-162
Identities = 265/322 (82%), Positives = 294/322 (91%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TGKEVA+KIIDKTQLN SLQKLFREVRIMK+L
Sbjct: 48 PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 107
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 227
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKKFL+L
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 287
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP+KR +LE IM+D+WMN G+E+DEL+PYVEP D+KD +R E +V +GY R+EI+ SL
Sbjct: 288 NPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLV 347
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
+Y++V ATYLLLG KS++ E
Sbjct: 348 GQRYNEVMATYLLLGYKSSELE 369
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/22 (63%), Positives = 17/22 (77%)
Query: 572 PNQLVFPRNVPSRSTFHSGQTR 593
P++ FPR V SRSTFH+GQ R
Sbjct: 527 PDRTNFPRGVSSRSTFHAGQLR 548
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 570 bits (1406), Expect = e-162
Identities = 265/322 (82%), Positives = 294/322 (91%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TGKEVA+KIIDKTQLN SLQKLFREVRIMK+L
Sbjct: 38 PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 97
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 98 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 157
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 158 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 217
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKKFL+L
Sbjct: 218 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 277
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP+KR +LE IM+D+WMN G+E+DEL+PYVEP D+KD +R E +V +GY R+EI+ SL
Sbjct: 278 NPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLV 337
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
+Y++V ATYLLLG KS++ E
Sbjct: 338 GQRYNEVMATYLLLGYKSSELE 359
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/22 (63%), Positives = 17/22 (77%)
Query: 572 PNQLVFPRNVPSRSTFHSGQTR 593
P++ FPR V SRSTFH+GQ R
Sbjct: 572 PDRTNFPRGVSSRSTFHAGQLR 593
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 570 bits (1406), Expect = e-162
Identities = 265/322 (82%), Positives = 294/322 (91%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TGKEVA+KIIDKTQLN SLQKLFREVRIMK+L
Sbjct: 15 PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 74
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKKFL+L
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 254
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP+KR +LE IM+D+WMN G+E+DEL+PYVEP D+KD +R E +V +GY R+EI+ SL
Sbjct: 255 NPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLV 314
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
+Y++V ATYLLLG KS++ E
Sbjct: 315 GQRYNEVMATYLLLGYKSSELE 336
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/22 (63%), Positives = 17/22 (77%)
Query: 572 PNQLVFPRNVPSRSTFHSGQTR 593
P++ FPR V SRSTFH+GQ R
Sbjct: 494 PDRTNFPRGVSSRSTFHAGQLR 515
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 570 bits (1406), Expect = e-162
Identities = 265/322 (82%), Positives = 294/322 (91%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TGKEVA+KIIDKTQLN SLQKLFREVRIMK+L
Sbjct: 48 PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 107
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD +MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 227
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKKFL+L
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 287
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP+KR +LE IM+D+WMN G+E+DEL+PYVEP D+KD +R E +V +GY R+EI+ SL
Sbjct: 288 NPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLV 347
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
+Y++V ATYLLLG KS++ E
Sbjct: 348 GQRYNEVMATYLLLGYKSSELE 369
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/22 (63%), Positives = 17/22 (77%)
Query: 572 PNQLVFPRNVPSRSTFHSGQTR 593
P++ FPR V SRSTFH+GQ R
Sbjct: 528 PDRTNFPRGVSSRSTFHAGQLR 549
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 568 bits (1402), Expect = e-161
Identities = 266/322 (82%), Positives = 289/322 (89%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+L KTIGKGNFAKVKLA+HV TG+EVA+KIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 55 PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLDG+MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 234
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKK LVL
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVL 294
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR SLE IM+D+WMN G+EE+EL+PY EP DF D KRI+ +V +G+ R EI +L
Sbjct: 295 NPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALI 354
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
KYD+V ATY+LLGRK + E
Sbjct: 355 NQKYDEVMATYILLGRKPPEFE 376
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 568 bits (1402), Expect = e-161
Identities = 266/322 (82%), Positives = 289/322 (89%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+L KTIGKGNFAKVKLA+HV TG+EVA+KIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 55 PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLDG+MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 234
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKK LVL
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVL 294
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR SLE IM+D+WMN G+EE+EL+PY EP DF D KRI+ +V +G+ R EI +L
Sbjct: 295 NPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALI 354
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
KYD+V ATY+LLGRK + E
Sbjct: 355 NQKYDEVMATYILLGRKPPEFE 376
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 568 bits (1402), Expect = e-161
Identities = 266/322 (82%), Positives = 289/322 (89%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+L KTIGKGNFAKVKLA+HV TG+EVA+KIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 55 PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLDG+MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 234
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKK LVL
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVL 294
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR SLE IM+D+WMN G+EE+EL+PY EP DF D KRI+ +V +G+ R EI +L
Sbjct: 295 NPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALI 354
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
KYD+V ATY+LLGRK + E
Sbjct: 355 NQKYDEVMATYILLGRKPPEFE 376
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 568 bits (1402), Expect = e-161
Identities = 266/322 (82%), Positives = 289/322 (89%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+L KTIGKGNFAKVKLA+HV TG+EVA+KIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 55 PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLDG+MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 234
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKK LVL
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVL 294
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR SLE IM+D+WMN G+EE+EL+PY EP DF D KRI+ +V +G+ R EI +L
Sbjct: 295 NPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALI 354
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
KYD+V ATY+LLGRK + E
Sbjct: 355 NQKYDEVMATYILLGRKPPEFE 376
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 562 bits (1388), Expect = e-159
Identities = 259/320 (80%), Positives = 291/320 (90%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PH+G Y+LL+TIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK L
Sbjct: 54 PHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYAS GEVFDYLV HGRMKEKEARAKFRQIVSAV YCH
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD E NIKIADFGFSNEFT G+KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVD+WSLGVILYTLVSGSLPFDG L+ELRERVLRGKYR+PFYMSTDCE++L++FLVL
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVL 293
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NPAKR +LE IM+DKW+N GYE +EL+PY EP++DF D KRIE +V +GY R+EI+ SL
Sbjct: 294 NPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLT 353
Query: 335 EAKYDDVFATYLLLGRKSTD 354
KY++V ATYLLLGRK+ +
Sbjct: 354 SQKYNEVTATYLLLGRKTEE 373
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 562 bits (1388), Expect = e-159
Identities = 259/320 (80%), Positives = 291/320 (90%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PH+G Y+LL+TIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK L
Sbjct: 54 PHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYAS GEVFDYLV HGRMKEKEARAKFRQIVSAV YCH
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD E NIKIADFGFSNEFT G+KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVD+WSLGVILYTLVSGSLPFDG L+ELRERVLRGKYR+PFYMSTDCE++L++FLVL
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVL 293
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NPAKR +LE IM+DKW+N GYE +EL+PY EP++DF D KRIE +V +GY R+EI+ SL
Sbjct: 294 NPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLT 353
Query: 335 EAKYDDVFATYLLLGRKSTD 354
KY++V ATYLLLGRK+ +
Sbjct: 354 SQKYNEVTATYLLLGRKTEE 373
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 562 bits (1388), Expect = e-159
Identities = 259/320 (80%), Positives = 291/320 (90%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PH+G Y+LL+TIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK L
Sbjct: 54 PHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYAS GEVFDYLV HGRMKEKEARAKFRQIVSAV YCH
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD E NIKIADFGFSNEFT G+KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVD+WSLGVILYTLVSGSLPFDG L+ELRERVLRGKYR+PFYMSTDCE++L++FLVL
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVL 293
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NPAKR +LE IM+DKW+N GYE +EL+PY EP++DF D KRIE +V +GY R+EI+ SL
Sbjct: 294 NPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLT 353
Query: 335 EAKYDDVFATYLLLGRKSTD 354
KY++V ATYLLLGRK+ +
Sbjct: 354 SQKYNEVTATYLLLGRKTEE 373
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 562 bits (1388), Expect = e-159
Identities = 259/320 (80%), Positives = 291/320 (90%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PH+G Y+LL+TIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK L
Sbjct: 55 PHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 114
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYAS GEVFDYLV HGRMKEKEARAKFRQIVSAV YCH
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 174
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD E NIKIADFGFSNEFT G+KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 175 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYD 234
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVD+WSLGVILYTLVSGSLPFDG L+ELRERVLRGKYR+PFYMSTDCE++L++FLVL
Sbjct: 235 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVL 294
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NPAKR +LE IM+DKW+N GYE +EL+PY EP++DF D KRIE +V +GY R+EI+ SL
Sbjct: 295 NPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLT 354
Query: 335 EAKYDDVFATYLLLGRKSTD 354
KY++V ATYLLLGRK+ +
Sbjct: 355 SQKYNEVTATYLLLGRKTEE 374
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 559 bits (1380), Expect = e-158
Identities = 258/320 (80%), Positives = 290/320 (90%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PH+G Y+LL+TIGKGN AKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK L
Sbjct: 54 PHVGNYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYAS GEVFDYLV HGRMKEKEARAKFRQIVSAV YCH
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD E NIKIADFGFSNEFT G+KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVD+WSLGVILYTLVSGSLPFDG L+ELRERVLRGKYR+PFYMSTDCE++L++FLVL
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVL 293
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NPAKR +LE IM+DKW+N GYE +EL+PY EP++DF D KRIE +V +GY R+EI+ SL
Sbjct: 294 NPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLT 353
Query: 335 EAKYDDVFATYLLLGRKSTD 354
KY++V ATYLLLGRK+ +
Sbjct: 354 SQKYNEVTATYLLLGRKTEE 373
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 559 bits (1380), Expect = e-158
Identities = 258/320 (80%), Positives = 290/320 (90%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PH+G Y+LL+TIGKGN AKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK L
Sbjct: 54 PHVGNYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNIVKLF+VIETEKTLYLVMEYAS GEVFDYLV HGRMKEKEARAKFRQIVSAV YCH
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLD E NIKIADFGFSNEFT G+KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVD+WSLGVILYTLVSGSLPFDG L+ELRERVLRGKYR+PFYMSTDCE++L++FLVL
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVL 293
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NPAKR +LE IM+DKW+N GYE +EL+PY EP++DF D KRIE +V +GY R+EI+ SL
Sbjct: 294 NPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLT 353
Query: 335 EAKYDDVFATYLLLGRKSTD 354
KY++V ATYLLLGRK+ +
Sbjct: 354 SQKYNEVTATYLLLGRKTEE 373
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 552 bits (1363), Expect = e-156
Identities = 263/343 (76%), Positives = 298/343 (86%), Gaps = 23/343 (6%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+LLKTIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 51 PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQ--------- 145
+HPNIVKLF+VIETEKTLYL+MEYASGGEVFDYLV HG+MKEKEAR+KFRQ
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIK 170
Query: 146 --------------IVSAVQYCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGA 191
IVSAVQYCHQKRI+HRDLKAENLLLD +MNIKIADFGFSNEFT G
Sbjct: 171 VQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGG 230
Query: 192 KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLR 251
KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLR
Sbjct: 231 KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR 290
Query: 252 GKYRIPFYMSTDCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
GKYRIPFYMSTDCENLLK+FLVLNP KR +LE IM+D+W+N G+EEDEL+P+VEP+ D
Sbjct: 291 GKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDIS 350
Query: 312 DHKRIEALVCLGYNRQEIEYSLAEAKYDDVFATYLLLGRKSTD 354
D KRI+ +V +GY+++EI+ SL++ KYD++ ATYLLLGRKS++
Sbjct: 351 DQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSE 393
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 505 bits (1245), Expect = e-142
Identities = 245/322 (76%), Positives = 267/322 (82%), Gaps = 22/322 (6%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+L KTIGKGNFAKVKLA+HV TG+EVA+KIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 55 PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNI GEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 115 NHPNI----------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 152
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLDG+MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 153 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 212
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKK LVL
Sbjct: 213 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVL 272
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR SLE IM+D+WMN G+EE+EL+PY EP DF D KRI+ +V +G+ R EI +L
Sbjct: 273 NPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALI 332
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
KYD+V ATY+LLGRK + E
Sbjct: 333 NQKYDEVMATYILLGRKPPEFE 354
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 505 bits (1245), Expect = e-142
Identities = 245/322 (76%), Positives = 267/322 (82%), Gaps = 22/322 (6%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
PHIG Y+L KTIGKGNFAKVKLA+HV TG+EVA+KIIDKTQLNP SLQKLFREVRIMK+L
Sbjct: 167 PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 226
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HPNI GEVFDYLV HGRMKEKEARAKFRQIVSAVQYCH
Sbjct: 227 NHPNI----------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 264
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
QK I+HRDLKAENLLLDG+MNIKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYD
Sbjct: 265 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYD 324
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
GPEVDVWSLGVILYTLVSGSLPFDG L+ELRERVLRGKYRIPFYMSTDCENLLKK LVL
Sbjct: 325 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVL 384
Query: 275 NPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLA 334
NP KR SLE IM+D+WMN G+EE+EL+PY EP DF D KRI+ +V +G+ R EI +L
Sbjct: 385 NPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALI 444
Query: 335 EAKYDDVFATYLLLGRKSTDPE 356
KYD+V ATY+LLGRK + E
Sbjct: 445 NQKYDEVMATYILLGRKPPEFE 466
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 470 bits (1158), Expect = e-132
Identities = 234/352 (66%), Positives = 269/352 (76%), Gaps = 31/352 (8%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ------------ 82
PH+G Y+LL+TIGKGNFAKVKLA+H+ TG+EVAIKIIDKTQLNP SLQ
Sbjct: 54 PHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL 113
Query: 83 ------KLFREVRIMKML---------DHPNIVKLFQVIETEKTLYLVME---YASGGEV 124
KLF + K L P + + L+L + GEV
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEPPTLSALPLCHLPLPLHLTLTPLGLCPAGEV 173
Query: 125 FDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDLKAENLLLDGEMNIKIADFGFS 184
FDYLV HGRMKEKEARAKFRQIVSAV YCHQK I+HRDLKAENLLLD E NIKIADFGFS
Sbjct: 174 FDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFS 233
Query: 185 NEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRE 244
NEFT G+KLDTFCGSPPYAAPELFQGKKYDGPEVD+WSLGVILYTLVSGSLPFDG L+E
Sbjct: 234 NEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKE 293
Query: 245 LRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYV 304
LRERVLRGKYR+PFYMSTDCE++L++FLVLNPAKR +LE IM+DKW+N GYE +EL+PY
Sbjct: 294 LRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYT 353
Query: 305 EPQQDFKDHKRIEALVCLGYNRQEIEYSLAEAKYDDVFATYLLLGRKSTDPE 356
EP++DF D KRIE +V +GY R+EI+ SL KY++V ATYLLLGRK T+P+
Sbjct: 354 EPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEVTATYLLLGRK-TEPD 404
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 423 bits (1043), Expect = e-118
Identities = 196/241 (81%), Positives = 212/241 (87%)
Query: 116 MEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDLKAENLLLDGEMN 175
MEYASGGEVFDYLV HGRMKEKEARAKFRQIVSAVQYCHQK I+HRDLKAENLLLDG+MN
Sbjct: 1 MEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN 60
Query: 176 IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 235
IKIADFGFSNEFT G KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL
Sbjct: 61 IKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 120
Query: 236 PFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKRASLESIMRDKWMNTGY 295
PFDG L+ELRERVLRGKYRIPFYMSTDCENLLKK LVLNP KR SLE IM+D+WMN G+
Sbjct: 121 PFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGH 180
Query: 296 EEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLAEAKYDDVFATYLLLGRKSTDP 355
EE+EL+PY EP DF D KRI+ +V +G+ R EI +L KYD+V ATY+LLGRK +
Sbjct: 181 EEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEF 240
Query: 356 E 356
E
Sbjct: 241 E 241
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 418 bits (1029), Expect = e-116
Identities = 190/239 (79%), Positives = 214/239 (89%)
Query: 116 MEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDLKAENLLLDGEMN 175
MEYAS GEVFDYLV HGRMKEKEARAKFRQIVSAV YCHQK I+HRDLKAENLLLD E N
Sbjct: 1 MEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN 60
Query: 176 IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 235
IKIADFGFSNEFT G+KLDTFCGSPPYAAPELFQGKKYDGPEVD+WSLGVILYTLVSGSL
Sbjct: 61 IKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL 120
Query: 236 PFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKRASLESIMRDKWMNTGY 295
PFDG L+ELRERVLRGKYR+PFYMSTDCE++L++FLVLNPAKR +LE IM+DKW+N GY
Sbjct: 121 PFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGY 180
Query: 296 EEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLAEAKYDDVFATYLLLGRKSTD 354
E +EL+PY EP++DF D KRIE +V +GY R+EI+ SL KY++V ATYLLLGRK+ +
Sbjct: 181 EGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEVTATYLLLGRKTEE 239
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 398 bits (979), Expect = e-110
Identities = 189/320 (59%), Positives = 244/320 (76%), Gaps = 8/320 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
IG Y++ +TIGKGNFA VK A H+ T +VAIKIIDKTQL+ +L+K+FREV+IMKML H
Sbjct: 113 IGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCH 172
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I++L+QV+ETE+ +YLV EYASGGE+FD+LV HGRM EKEAR KF+QIV+AV +CH +
Sbjct: 173 PHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCR 232
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
I+HRDLKAENLLLD +NIKIADFGFSN FTPG L T+CGSPPYAAPELF+GK+YDGP
Sbjct: 233 NIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGP 292
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
+VD+WSLGV+LY LV G+LPFDGSTL+ LR RVL GK+RIPF+MST+CE+L++ LVL+P
Sbjct: 293 KVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDP 352
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIE--------ALVCLGYNRQE 328
KR S+E I + KWM G + + Q K+ ++++ A+ +G ++++
Sbjct: 353 NKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQ 412
Query: 329 IEYSLAEAKYDDVFATYLLL 348
SL YD A Y LL
Sbjct: 413 TLQSLRSDAYDHYSAIYSLL 432
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 393 bits (968), Expect = e-109
Identities = 180/283 (63%), Positives = 229/283 (80%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
IG Y++ +TIGKGNFA VK A H+ T +VAIKIIDKTQL+ +L+K+FREV+IMKML H
Sbjct: 5 IGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCH 64
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I++L+QV+ETE+ +YLV EYASGGE+FD+LV HGRM EKEAR KF+QIV+AV +CH +
Sbjct: 65 PHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCR 124
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
I+HRDLKAENLLLD +NIKIADFGFSN FTPG L T+CGSPPYAAPELF+GK+YDGP
Sbjct: 125 NIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGP 184
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
+VD+WSLGV+LY LV G+LPFDGSTL+ LR RVL GK+RIPF+MST+CE+L++ LVL+P
Sbjct: 185 KVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDP 244
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEAL 319
KR S+E I + KWM G + + Q K+ ++++ L
Sbjct: 245 NKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPL 287
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 365 bits (897), Expect = e-100
Identities = 175/319 (54%), Positives = 232/319 (72%), Gaps = 9/319 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
+G Y + T+GKGNFA VKL +H T EVAIKIIDK+QL+ +L+K++REV+IMKMLDH
Sbjct: 17 VGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDH 76
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I+KL+QV+ET+ LYLV EYA GE+FDYL HGR+ E EAR KF QI+SAV YCH +
Sbjct: 77 PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 136
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
+I+HRDLKAENLLLD MNIKIADFGF N F G L T+CGSPPYAAPE+F+G++Y+GP
Sbjct: 137 KIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGP 196
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
++D+WS+GV+LY LV G+LPFDG TL LR+RVL G++RIP++MS DCE+L+++ LVL+P
Sbjct: 197 QLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDP 256
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKD-------HKRIEALVCLGYNRQEI 329
+KR ++ I KWM E RP + PQ+ + + + + LG ++Q+
Sbjct: 257 SKRLTIAQIKEHKWML--IEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKT 314
Query: 330 EYSLAEAKYDDVFATYLLL 348
SL Y+ A Y LL
Sbjct: 315 IESLQNKSYNHFAAIYFLL 333
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 365 bits (897), Expect = e-100
Identities = 175/319 (54%), Positives = 232/319 (72%), Gaps = 9/319 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
+G Y + T+GKGNFA VKL +H T EVAIKIIDK+QL+ +L+K++REV+IMKMLDH
Sbjct: 17 VGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDH 76
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I+KL+QV+ET+ LYLV EYA GE+FDYL HGR+ E EAR KF QI+SAV YCH +
Sbjct: 77 PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 136
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
+I+HRDLKAENLLLD MNIKIADFGF N F G L T+CGSPPYAAPE+F+G++Y+GP
Sbjct: 137 KIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGP 196
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
++D+WS+GV+LY LV G+LPFDG TL LR+RVL G++RIP++MS DCE+L+++ LVL+P
Sbjct: 197 QLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDP 256
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKD-------HKRIEALVCLGYNRQEI 329
+KR ++ I KWM E RP + PQ+ + + + + LG ++Q+
Sbjct: 257 SKRLTIAQIKEHKWML--IEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKT 314
Query: 330 EYSLAEAKYDDVFATYLLL 348
SL Y+ A Y LL
Sbjct: 315 IESLQNKSYNHFAAIYFLL 333
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 365 bits (897), Expect = e-100
Identities = 175/319 (54%), Positives = 232/319 (72%), Gaps = 9/319 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
+G Y + T+GKGNFA VKL +H T EVAIKIIDK+QL+ +L+K++REV+IMKMLDH
Sbjct: 15 VGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDH 74
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I+KL+QV+ET+ LYLV EYA GE+FDYL HGR+ E EAR KF QI+SAV YCH +
Sbjct: 75 PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 134
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
+I+HRDLKAENLLLD MNIKIADFGF N F G L T+CGSPPYAAPE+F+G++Y+GP
Sbjct: 135 KIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGP 194
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
++D+WS+GV+LY LV G+LPFDG TL LR+RVL G++RIP++MS DCE+L+++ LVL+P
Sbjct: 195 QLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDP 254
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKD-------HKRIEALVCLGYNRQEI 329
+KR ++ I KWM E RP + PQ+ + + + + LG ++Q+
Sbjct: 255 SKRLTIAQIKEHKWML--IEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKT 312
Query: 330 EYSLAEAKYDDVFATYLLL 348
SL Y+ A Y LL
Sbjct: 313 IESLQNKSYNHFAAIYFLL 331
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 365 bits (897), Expect = e-100
Identities = 175/319 (54%), Positives = 232/319 (72%), Gaps = 9/319 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
+G Y + T+GKGNFA VKL +H T EVAIKIIDK+QL+ +L+K++REV+IMKMLDH
Sbjct: 41 VGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDH 100
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I+KL+QV+ET+ LYLV EYA GE+FDYL HGR+ E EAR KF QI+SAV YCH +
Sbjct: 101 PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 160
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
+I+HRDLKAENLLLD MNIKIADFGF N F G L T+CGSPPYAAPE+F+G++Y+GP
Sbjct: 161 KIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGP 220
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
++D+WS+GV+LY LV G+LPFDG TL LR+RVL G++RIP++MS DCE+L+++ LVL+P
Sbjct: 221 QLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDP 280
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKD-------HKRIEALVCLGYNRQEI 329
+KR ++ I KWM E RP + PQ+ + + + + LG ++Q+
Sbjct: 281 SKRLTIAQIKEHKWML--IEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKT 338
Query: 330 EYSLAEAKYDDVFATYLLL 348
SL Y+ A Y LL
Sbjct: 339 IESLQNKSYNHFAAIYFLL 357
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 355 bits (872), Expect = 4e-97
Identities = 165/319 (51%), Positives = 228/319 (71%), Gaps = 8/319 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
+G Y + +T+GKGNFA VKLA+H T +VAIKIIDKT+L+ +L+K++REV++MK+L+H
Sbjct: 24 VGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNH 83
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I+KL+QV+ET+ LY+V E+A GE+FDYL +G + E EAR KF QI+SAV+YCH
Sbjct: 84 PHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
I+HRDLK ENLLLDG M+IK+ADFGF N + G L T+CGSPPYAAPE+F+GK+Y+GP
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 203
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
++D+WSLGV+LY LV GSLPFDG L LR+RVL G++RIPF+MS DCE+L+++ LV++P
Sbjct: 204 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP 263
Query: 277 AKRASLESIMRDKWMNT-------GYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEI 329
A+R ++ I + +WM Y D+ D + + + LG +RQ
Sbjct: 264 ARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDY-DEQALGIMQTLGVDRQRT 322
Query: 330 EYSLAEAKYDDVFATYLLL 348
SL + Y+ A Y LL
Sbjct: 323 VESLQNSSYNHFAAIYYLL 341
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 355 bits (872), Expect = 4e-97
Identities = 165/319 (51%), Positives = 228/319 (71%), Gaps = 8/319 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
+G Y + +T+GKGNFA VKLA+H T +VAIKIIDKT+L+ +L+K++REV++MK+L+H
Sbjct: 5 VGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNH 64
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I+KL+QV+ET+ LY+V E+A GE+FDYL +G + E EAR KF QI+SAV+YCH
Sbjct: 65 PHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 124
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
I+HRDLK ENLLLDG M+IK+ADFGF N + G L T+CGSPPYAAPE+F+GK+Y+GP
Sbjct: 125 HIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 184
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
++D+WSLGV+LY LV GSLPFDG L LR+RVL G++RIPF+MS DCE+L+++ LV++P
Sbjct: 185 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP 244
Query: 277 AKRASLESIMRDKWMNT-------GYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEI 329
A+R ++ I + +WM Y D+ D + + + LG +RQ
Sbjct: 245 ARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDY-DEQALGIMQTLGVDRQRT 303
Query: 330 EYSLAEAKYDDVFATYLLL 348
SL + Y+ A Y LL
Sbjct: 304 VESLQNSSYNHFAAIYYLL 322
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 355 bits (872), Expect = 4e-97
Identities = 165/319 (51%), Positives = 228/319 (71%), Gaps = 8/319 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
+G Y + +T+GKGNFA VKLA+H T +VAIKIIDKT+L+ +L+K++REV++MK+L+H
Sbjct: 24 VGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNH 83
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I+KL+QV+ET+ LY+V E+A GE+FDYL +G + E EAR KF QI+SAV+YCH
Sbjct: 84 PHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
I+HRDLK ENLLLDG M+IK+ADFGF N + G L T+CGSPPYAAPE+F+GK+Y+GP
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 203
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
++D+WSLGV+LY LV GSLPFDG L LR+RVL G++RIPF+MS DCE+L+++ LV++P
Sbjct: 204 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP 263
Query: 277 AKRASLESIMRDKWMNT-------GYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEI 329
A+R ++ I + +WM Y D+ D + + + LG +RQ
Sbjct: 264 ARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDY-DEQALGIMQTLGVDRQRT 322
Query: 330 EYSLAEAKYDDVFATYLLL 348
SL + Y+ A Y LL
Sbjct: 323 VESLQNSSYNHFAAIYYLL 341
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 349 bits (857), Expect = 2e-95
Identities = 165/322 (51%), Positives = 228/322 (70%), Gaps = 11/322 (3%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
+G Y + +T+GKGNFA VKLA+H T +VAIKIIDKT+L+ +L+K++REV++MK+L+H
Sbjct: 24 VGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNH 83
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I+KL+QV+ET+ LY+V E+A GE+FDYL +G + E EAR KF QI+SAV+YCH
Sbjct: 84 PHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143
Query: 157 RIIHRDLKAENLLLDGEMNIKIA---DFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKY 213
I+HRDLK ENLLLDG M+IK+A DFGF N + G L T+CGSPPYAAPE+F+GK+Y
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLAGTEDFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEY 203
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
+GP++D+WSLGV+LY LV GSLPFDG L LR+RVL G++RIPF+MS DCE+L+++ LV
Sbjct: 204 EGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLV 263
Query: 274 LNPAKRASLESIMRDKWMNT-------GYEEDELRPYVEPQQDFKDHKRIEALVCLGYNR 326
++PA+R ++ I + +WM Y D+ D + + + LG +R
Sbjct: 264 VDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDY-DEQALGIMQTLGVDR 322
Query: 327 QEIEYSLAEAKYDDVFATYLLL 348
Q SL + Y+ A Y LL
Sbjct: 323 QRTVESLQNSSYNHFAAIYYLL 344
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 284 bits (697), Expect = 6e-76
Identities = 134/271 (49%), Positives = 188/271 (69%), Gaps = 2/271 (0%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H TG++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 30 YVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE 89
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQIVSA+ +CH
Sbjct: 90 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 149
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 150 YSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDG 209
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
D+WS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ + +
Sbjct: 210 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 269
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEP 306
P KR SLE I + W G E + P +EP
Sbjct: 270 PEKRLSLEQIQKHPWYLGGKHEPD--PCLEP 298
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 284 bits (697), Expect = 6e-76
Identities = 134/271 (49%), Positives = 188/271 (69%), Gaps = 2/271 (0%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H TG++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 30 YVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE 89
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQIVSA+ +CH
Sbjct: 90 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 149
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 150 YSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDG 209
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
D+WS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ + +
Sbjct: 210 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 269
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEP 306
P KR SLE I + W G E + P +EP
Sbjct: 270 PEKRLSLEQIQKHPWYLGGKHEPD--PCLEP 298
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 284 bits (697), Expect = 6e-76
Identities = 134/271 (49%), Positives = 188/271 (69%), Gaps = 2/271 (0%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H TG++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 30 YVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE 89
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQIVSA+ +CH
Sbjct: 90 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 149
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 150 YSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDG 209
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
D+WS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ + +
Sbjct: 210 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 269
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEP 306
P KR SLE I + W G E + P +EP
Sbjct: 270 PEKRLSLEQIQKHPWYLGGKHEPD--PCLEP 298
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 284 bits (697), Expect = 6e-76
Identities = 134/271 (49%), Positives = 188/271 (69%), Gaps = 2/271 (0%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H TG++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 46 YVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE 105
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQIVSA+ +CH
Sbjct: 106 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 165
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 166 YSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDG 225
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
D+WS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ + +
Sbjct: 226 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 285
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEP 306
P KR SLE I + W G E + P +EP
Sbjct: 286 PEKRLSLEQIQKHPWYLGGKHEPD--PCLEP 314
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 277 bits (680), Expect = 7e-74
Identities = 129/264 (48%), Positives = 185/264 (70%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H T ++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 15 YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +CH
Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+ DVWS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ + ++
Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVD 254
Query: 276 PAKRASLESIMRDKWMNTGYEEDE 299
A+R +LE I + W G E E
Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPE 278
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 276 bits (676), Expect = 2e-73
Identities = 129/264 (48%), Positives = 184/264 (69%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H T ++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 15 YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +CH
Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+ DVWS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ ++
Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMSEVD 254
Query: 276 PAKRASLESIMRDKWMNTGYEEDE 299
A+R +LE I + W G E E
Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPE 278
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 276 bits (676), Expect = 2e-73
Identities = 129/264 (48%), Positives = 184/264 (69%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H T ++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 15 YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +CH
Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+ DVWS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ ++
Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMSEVD 254
Query: 276 PAKRASLESIMRDKWMNTGYEEDE 299
A+R +LE I + W G E E
Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPE 278
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 276 bits (676), Expect = 2e-73
Identities = 129/264 (48%), Positives = 184/264 (69%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H T ++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 15 YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +CH
Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+ DVWS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ ++
Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMSEVD 254
Query: 276 PAKRASLESIMRDKWMNTGYEEDE 299
A+R +LE I + W G E E
Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPE 278
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 276 bits (676), Expect = 2e-73
Identities = 129/264 (48%), Positives = 184/264 (69%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H T ++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 15 YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +CH
Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+ DVWS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ ++
Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMSEVD 254
Query: 276 PAKRASLESIMRDKWMNTGYEEDE 299
A+R +LE I + W G E E
Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPE 278
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 276 bits (676), Expect = 2e-73
Identities = 129/264 (48%), Positives = 184/264 (69%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H T ++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 15 YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +CH
Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+ DVWS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ ++
Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMSEVD 254
Query: 276 PAKRASLESIMRDKWMNTGYEEDE 299
A+R +LE I + W G E E
Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPE 278
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 276 bits (676), Expect = 2e-73
Identities = 129/264 (48%), Positives = 184/264 (69%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLD 95
++G Y+L KT+GKG VKL H T ++VAIKI+++ +L+ L K+ RE+ I+K+++
Sbjct: 15 YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +CH
Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+ DVWS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+ ++
Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMSEVD 254
Query: 276 PAKRASLESIMRDKWMNTGYEEDE 299
A+R +LE I + W G E E
Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPE 278
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 275 bits (675), Expect = 3e-73
Identities = 139/323 (43%), Positives = 205/323 (63%), Gaps = 10/323 (3%)
Query: 38 GKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHP 97
G Y L KT+G+G+FA VKLA+HV TG++VA+K+IDKT+L+ + LF+EVR MK++ HP
Sbjct: 15 GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHP 74
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGR-MKEKEARAKFRQIVSAVQYCHQK 156
NIV+L++VI+T+ LYL++E GG++FDY++ H + E A+ F QIV A+ YCH+
Sbjct: 75 NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 134
Query: 157 RIIHRDLKAENLLLDGEMN-IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN++ + +K+ DFGFSN+F PG KL T CGS Y+APE+ G +YD
Sbjct: 135 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
P VD+WSLGVIL+ LV G PF + E ++ KY +P ++S +C++L+ + L +
Sbjct: 195 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRD 254
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK-----DHKRIEALVCLG--YNRQE 328
P +RASLE I W+ G + Y P +K +H I + LG +R
Sbjct: 255 PKRRASLEEIENHPWLQ-GVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDA 313
Query: 329 IEYSLAEAKYDDVFATYLLLGRK 351
I +L +Y+ + ATY LL +
Sbjct: 314 IVEALETNRYNHITATYFLLAER 336
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 273 bits (669), Expect = 1e-72
Identities = 138/323 (42%), Positives = 204/323 (63%), Gaps = 10/323 (3%)
Query: 38 GKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHP 97
G Y L KT+G+G+FA VKLA+HV TG++VA+K+IDKT+L+ + LF+EVR MK++ HP
Sbjct: 14 GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHP 73
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGR-MKEKEARAKFRQIVSAVQYCHQK 156
NIV+L++VI+T+ LYL++E GG++FDY++ H + E A+ F QIV A+ YCH+
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133
Query: 157 RIIHRDLKAENLLLDGEMN-IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN++ + +K+ DFGFSN+F PG KL T CGS Y+APE+ G +YD
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
P VD+WSLGVIL+ LV G PF + E ++ KY +P ++S +C++L+ + L +
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRD 253
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK-----DHKRIEALVCLG--YNRQE 328
P +RA LE I W+ G + Y P +K +H I + LG +R
Sbjct: 254 PKRRAYLEEIENHPWLQ-GVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDA 312
Query: 329 IEYSLAEAKYDDVFATYLLLGRK 351
I +L +Y+ + ATY LL +
Sbjct: 313 IVEALETNRYNHITATYFLLAER 335
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 270 bits (662), Expect = 1e-71
Identities = 137/323 (42%), Positives = 203/323 (62%), Gaps = 10/323 (3%)
Query: 38 GKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHP 97
G Y L KT+G+G+FA VKLA+HV TG++VA+K+IDKT+L+ + LF+EVR MK++ HP
Sbjct: 14 GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHP 73
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGR-MKEKEARAKFRQIVSAVQYCHQK 156
NIV+L++VI+T+ LYL++E G++FDY++ H + E + F QIV A+ YCH+
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKL 133
Query: 157 RIIHRDLKAENLLLDGEMN-IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN++ + +K+ DFGFSN+F PG KL T CGS Y+APE+ G +YD
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
P VD+WSLGVIL+ LV G PF + E ++ KY +P ++S +C++L+ + L +
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRD 253
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK-----DHKRIEALVCLG--YNRQE 328
P +RASLE I W+ G + Y P +K +H I + LG +R
Sbjct: 254 PKRRASLEEIENHPWLQ-GVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDA 312
Query: 329 IEYSLAEAKYDDVFATYLLLGRK 351
I +L +Y+ + ATY LL +
Sbjct: 313 IVEALETNRYNHITATYFLLAER 335
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 266 bits (653), Expect = 1e-70
Identities = 124/259 (47%), Positives = 174/259 (67%), Gaps = 1/259 (0%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ +H TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 13 IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T ++VMEY SGGE+FDY+ HGR++E EAR F+QI+SAV YCH+
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP Y APE+ G+ Y G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYTAPEVISGRLYAG 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
PEVD+WS GVILY L+ G+LPFD + L +++ G + IP Y++ LL L ++
Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252
Query: 276 PAKRASLESIMRDKWMNTG 294
P KRA+++ I +W G
Sbjct: 253 PLKRATIKDIREHEWFKQG 271
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 266 bits (653), Expect = 1e-70
Identities = 129/282 (45%), Positives = 184/282 (65%), Gaps = 6/282 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ +H TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 13 IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T ++VMEY SGGE+FDY+ HGR++E EAR F+QI+SAV YCH+
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+ Y G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
PEVD+WS GVILY L+ G+LPFD + L +++ G + IP Y++ LL L ++
Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIE 317
P KRA+++ I +W + +L Y+ P+ D I+
Sbjct: 253 PLKRATIKDIREHEWF-----KQDLPSYLFPEDPSYDANVID 289
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 266 bits (653), Expect = 1e-70
Identities = 129/282 (45%), Positives = 184/282 (65%), Gaps = 6/282 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ +H TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 13 IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T ++VMEY SGGE+FDY+ HGR++E EAR F+QI+SAV YCH+
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+ Y G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
PEVD+WS GVILY L+ G+LPFD + L +++ G + IP Y++ LL L ++
Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIE 317
P KRA+++ I +W + +L Y+ P+ D I+
Sbjct: 253 PLKRATIKDIREHEWF-----KQDLPSYLFPEDPSYDANVID 289
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 266 bits (653), Expect = 1e-70
Identities = 129/282 (45%), Positives = 184/282 (65%), Gaps = 6/282 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ +H TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 13 IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T ++VMEY SGGE+FDY+ HGR++E EAR F+QI+SAV YCH+
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+ Y G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
PEVD+WS GVILY L+ G+LPFD + L +++ G + IP Y++ LL L ++
Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIE 317
P KRA+++ I +W + +L Y+ P+ D I+
Sbjct: 253 PLKRATIKDIREHEWF-----KQDLPSYLFPEDPSYDANVID 289
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 266 bits (653), Expect = 1e-70
Identities = 129/282 (45%), Positives = 184/282 (65%), Gaps = 6/282 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ +H TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 13 IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T ++VMEY SGGE+FDY+ HGR++E EAR F+QI+SAV YCH+
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+ Y G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
PEVD+WS GVILY L+ G+LPFD + L +++ G + IP Y++ LL L ++
Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIE 317
P KRA+++ I +W + +L Y+ P+ D I+
Sbjct: 253 PLKRATIKDIREHEWF-----KQDLPSYLFPEDPSYDANVID 289
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 265 bits (650), Expect = 3e-70
Identities = 124/255 (48%), Positives = 175/255 (68%), Gaps = 1/255 (0%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ KH TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 15 IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFR 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T +++VMEY SGGE+FDY+ +GR+ EKE+R F+QI+S V YCH+
Sbjct: 75 HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+ Y G
Sbjct: 135 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
PEVD+WS GVILY L+ G+LPFD + L +++ G + P Y++ +LLK L ++
Sbjct: 195 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 254
Query: 276 PAKRASLESIMRDKW 290
P KRAS++ I +W
Sbjct: 255 PMKRASIKDIREHEW 269
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 264 bits (648), Expect = 5e-70
Identities = 128/282 (45%), Positives = 183/282 (64%), Gaps = 6/282 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KV + +H TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 13 IGHYVLGDTLGVGTFGKVNIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T ++VMEY SGGE+FDY+ HGR++E EAR F+QI+SAV YCH+
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+ Y G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
PEVD+WS GVILY L+ G+LPFD + L +++ G + IP Y++ LL L ++
Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252
Query: 276 PAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIE 317
P KRA+++ I +W + +L Y+ P+ D I+
Sbjct: 253 PLKRATIKDIREHEWF-----KQDLPSYLFPEDPSYDANVID 289
>BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein.
Length = 1102
Score = 264 bits (647), Expect = 7e-70
Identities = 125/223 (56%), Positives = 161/223 (72%), Gaps = 8/223 (3%)
Query: 134 MKEKEARAKFRQIVSAVQYCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKL 193
M EKEAR KF+QIV+AV +CH + I+HRDLKAENLLLD +NIKIADFGFSN FTPG L
Sbjct: 1 MAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLL 60
Query: 194 DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGK 253
T+CGSPPYAAPELF+GK+YDGP+VD+WSLGV+LY LV G+LPFDGSTL+ LR RVL GK
Sbjct: 61 KTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGK 120
Query: 254 YRIPFYMSTDCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDH 313
+RIPF+MST+CE+L++ LVL+P KR S+E I + KWM G + + Q K+
Sbjct: 121 FRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEE 180
Query: 314 KRIE--------ALVCLGYNRQEIEYSLAEAKYDDVFATYLLL 348
++++ A+ +G ++++ SL YD A Y LL
Sbjct: 181 RQVDPLNEDVLLAMEDMGLDKEQTLQSLRSDAYDHYSAIYSLL 223
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 264 bits (647), Expect = 7e-70
Identities = 123/255 (48%), Positives = 175/255 (68%), Gaps = 1/255 (0%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ KH TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 15 IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFR 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T +++VMEY SGGE+FDY+ +GR+ EKE+R F+QI+S V YCH+
Sbjct: 75 HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+ Y G
Sbjct: 135 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 194
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
PEVD+WS GVILY L+ G+LPFD + L +++ G + P Y++ +LLK L ++
Sbjct: 195 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 254
Query: 276 PAKRASLESIMRDKW 290
P KRA+++ I +W
Sbjct: 255 PMKRATIKDIREHEW 269
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 262 bits (642), Expect = 3e-69
Identities = 130/298 (43%), Positives = 192/298 (64%), Gaps = 8/298 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
IG Y++ IG GNF++VKL H T ++VAIKI+DKT+L+ + + L RE+ M+ L H
Sbjct: 71 IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
PNI++L++V+ET L+LVMEYA GGE+F + G++ E E++ F QIVSAV++ H+
Sbjct: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190
Query: 157 RIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
+IIHRDLKAEN+ +K+ DFGFS G L+TFCGSPPYAAPELF+ + Y G
Sbjct: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
VD+W+LGV+LY +V+G++PF T+ +L++ +L G Y +P ++S C L++ L P
Sbjct: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK-DHKRIEALVCLGYNRQEIEYSL 333
+R ++ IM D+WM G PY P + F+ D K + L E++ +L
Sbjct: 311 TERYGIDCIMNDEWMQ-GV------PYPTPLEPFQLDPKHLSETSTLKEEENEVKSTL 361
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 261 bits (640), Expect = 5e-69
Identities = 127/258 (49%), Positives = 175/258 (67%), Gaps = 3/258 (1%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 97
+Y+ L+T+GKG + KVK A+ +G+ VAIK I K ++ + L + RE+ IM L+HP
Sbjct: 52 RYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHP 110
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
+I+ + +V E + +VMEYAS G+++DY+ ++ E+EAR FRQIVSAV YCHQ R
Sbjct: 111 HIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNR 170
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++HRDLK EN+LLD NIKIADFG SN + G L TFCGSP YA+PE+ GK Y GPE
Sbjct: 171 VVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPE 230
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD WSLGV+LY LV G++PFDG + L +++ G YR P S C L++ L++NP
Sbjct: 231 VDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPT 289
Query: 278 KRASLESIMRDKWMNTGY 295
+RA+LE + W+N GY
Sbjct: 290 RRATLEDVASHWWVNWGY 307
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 261 bits (640), Expect = 5e-69
Identities = 127/258 (49%), Positives = 175/258 (67%), Gaps = 3/258 (1%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 97
+Y+ L+T+GKG + KVK A+ +G+ VAIK I K ++ + L + RE+ IM L+HP
Sbjct: 52 RYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHP 110
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
+I+ + +V E + +VMEYAS G+++DY+ ++ E+EAR FRQIVSAV YCHQ R
Sbjct: 111 HIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNR 170
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++HRDLK EN+LLD NIKIADFG SN + G L TFCGSP YA+PE+ GK Y GPE
Sbjct: 171 VVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPE 230
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD WSLGV+LY LV G++PFDG + L +++ G YR P S C L++ L++NP
Sbjct: 231 VDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPT 289
Query: 278 KRASLESIMRDKWMNTGY 295
+RA+LE + W+N GY
Sbjct: 290 RRATLEDVASHWWVNWGY 307
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 259 bits (635), Expect = 2e-68
Identities = 121/246 (49%), Positives = 173/246 (70%)
Query: 54 VKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLY 113
VKL H T ++VAIKI+++ +L+ L K+ RE+ I+K+++HP+++KL V E +K LY
Sbjct: 79 VKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLY 138
Query: 114 LVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDLKAENLLLDGE 173
LV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +CH I HRDLK ENLLLD +
Sbjct: 139 LVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEK 198
Query: 174 MNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSG 233
NI+IADFG ++ + L+T CGSP YA PE+ +G+KYDG + DVWS GVIL+ L+ G
Sbjct: 199 NNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVG 258
Query: 234 SLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKRASLESIMRDKWMNT 293
+LPFD LR+L E+V RG + +P ++ DC++LL+ + ++ A+R +LE I + W
Sbjct: 259 ALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIG 318
Query: 294 GYEEDE 299
G E E
Sbjct: 319 GKNEPE 324
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 257 bits (630), Expect = 8e-68
Identities = 122/259 (47%), Positives = 175/259 (67%), Gaps = 2/259 (0%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 97
+Y+L +T+GKG + KVK A +G+ VAIK I K ++ + + + RE+ IM L+HP
Sbjct: 91 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHP 150
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
+I+ +++V E + + ++MEYAS GE++DY+ R+ E+E R FRQIVSAV YCH+
Sbjct: 151 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNG 210
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++HRDLK EN+LLD NIKIADFG SN + L TFCGSP YA+PE+ G+ Y GPE
Sbjct: 211 VVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPE 270
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W+LGV+LYTLV G++PFDG + L ++ G+YR P S D L++ L++NP
Sbjct: 271 VDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPS-DARGLIRWMLMVNPD 329
Query: 278 KRASLESIMRDKWMNTGYE 296
+RA++E I W+N GY+
Sbjct: 330 RRATIEDIANHWWVNWGYK 348
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 251 bits (615), Expect = 5e-66
Identities = 135/312 (43%), Positives = 188/312 (60%), Gaps = 5/312 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L +TIG G FAKVKLA H+ TG+ VAIKI+DK L L ++ E+ +K L H +I
Sbjct: 16 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLG-SDLPRIKTEIEALKNLRHQHI 74
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
+L+ V+ET +++V+EY GGE+FDY++ R+ E+E R FRQIVSAV Y H +
Sbjct: 75 CQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYA 134
Query: 160 HRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D +K+ DFG + G K L T CGS YAAPEL QGK Y G
Sbjct: 135 HRDLKPENLLFDEYHKLKLIDFGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 193
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
E DVWS+G++LY L+ G LPFD + L ++++RGKY +P ++S LL++ L ++P
Sbjct: 194 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDP 253
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLAEA 336
KR S+++++ W+ Y P D E V NRQ +E ++
Sbjct: 254 KKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLW 313
Query: 337 KYDDVFATYLLL 348
+YD + ATYLLL
Sbjct: 314 QYDHLTATYLLL 325
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 251 bits (615), Expect = 5e-66
Identities = 135/312 (43%), Positives = 188/312 (60%), Gaps = 5/312 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L +TIG G FAKVKLA H+ TG+ VAIKI+DK L L ++ E+ +K L H +I
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLG-SDLPRIKTEIEALKNLRHQHI 69
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
+L+ V+ET +++V+EY GGE+FDY++ R+ E+E R FRQIVSAV Y H +
Sbjct: 70 CQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYA 129
Query: 160 HRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D +K+ DFG + G K L T CGS YAAPEL QGK Y G
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 188
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
E DVWS+G++LY L+ G LPFD + L ++++RGKY +P ++S LL++ L ++P
Sbjct: 189 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDP 248
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLAEA 336
KR S+++++ W+ Y P D E V NRQ +E ++
Sbjct: 249 KKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLW 308
Query: 337 KYDDVFATYLLL 348
+YD + ATYLLL
Sbjct: 309 QYDHLTATYLLL 320
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 251 bits (615), Expect = 5e-66
Identities = 135/312 (43%), Positives = 188/312 (60%), Gaps = 5/312 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L +TIG G FAKVKLA H+ TG+ VAIKI+DK L L ++ E+ +K L H +I
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLG-SDLPRIKTEIEALKNLRHQHI 69
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
+L+ V+ET +++V+EY GGE+FDY++ R+ E+E R FRQIVSAV Y H +
Sbjct: 70 CQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYA 129
Query: 160 HRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D +K+ DFG + G K L T CGS YAAPEL QGK Y G
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 188
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
E DVWS+G++LY L+ G LPFD + L ++++RGKY +P ++S LL++ L ++P
Sbjct: 189 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDP 248
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLAEA 336
KR S+++++ W+ Y P D E V NRQ +E ++
Sbjct: 249 KKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLW 308
Query: 337 KYDDVFATYLLL 348
+YD + ATYLLL
Sbjct: 309 QYDHLTATYLLL 320
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 251 bits (615), Expect = 5e-66
Identities = 135/312 (43%), Positives = 188/312 (60%), Gaps = 5/312 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L +TIG G FAKVKLA H+ TG+ VAIKI+DK L L ++ E+ +K L H +I
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLG-SDLPRIKTEIEALKNLRHQHI 69
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
+L+ V+ET +++V+EY GGE+FDY++ R+ E+E R FRQIVSAV Y H +
Sbjct: 70 CQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYA 129
Query: 160 HRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D +K+ DFG + G K L T CGS YAAPEL QGK Y G
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 188
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
E DVWS+G++LY L+ G LPFD + L ++++RGKY +P ++S LL++ L ++P
Sbjct: 189 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDP 248
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLAEA 336
KR S+++++ W+ Y P D E V NRQ +E ++
Sbjct: 249 KKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLW 308
Query: 337 KYDDVFATYLLL 348
+YD + ATYLLL
Sbjct: 309 QYDHLTATYLLL 320
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 251 bits (615), Expect = 5e-66
Identities = 135/312 (43%), Positives = 188/312 (60%), Gaps = 5/312 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L +TIG G FAKVKLA H+ TG+ VAIKI+DK L L ++ E+ +K L H +I
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLG-SDLPRIKTEIEALKNLRHQHI 69
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
+L+ V+ET +++V+EY GGE+FDY++ R+ E+E R FRQIVSAV Y H +
Sbjct: 70 CQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYA 129
Query: 160 HRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D +K+ DFG + G K L T CGS YAAPEL QGK Y G
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 188
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNP 276
E DVWS+G++LY L+ G LPFD + L ++++RGKY +P ++S LL++ L ++P
Sbjct: 189 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDP 248
Query: 277 AKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFKDHKRIEALVCLGYNRQEIEYSLAEA 336
KR S+++++ W+ Y P D E V NRQ +E ++
Sbjct: 249 KKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLW 308
Query: 337 KYDDVFATYLLL 348
+YD + ATYLLL
Sbjct: 309 QYDHLTATYLLL 320
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 248 bits (608), Expect = 4e-65
Identities = 123/270 (45%), Positives = 175/270 (64%), Gaps = 16/270 (5%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ KH TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 24 IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFR 83
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGR---------------MKEKEAR 140
HP+I+KL+QVI T +++VMEY SGGE+FDY+ +GR + EKE+R
Sbjct: 84 HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKESR 143
Query: 141 AKFRQIVSAVQYCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSP 200
F+QI+S V YCH+ ++HRDLK EN+LLD MN KIADFG SN + G L T CGSP
Sbjct: 144 RLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSP 203
Query: 201 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYM 260
YAAPE+ G+ Y GPEVD+WS GVILY L+ G+LPFD + L +++ G + P Y+
Sbjct: 204 NYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYL 263
Query: 261 STDCENLLKKFLVLNPAKRASLESIMRDKW 290
+ +LLK L ++P KRA+++ I +W
Sbjct: 264 NPSVISLLKHMLQVDPMKRATIKDIREHEW 293
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 248 bits (607), Expect = 5e-65
Identities = 116/237 (48%), Positives = 164/237 (69%), Gaps = 2/237 (0%)
Query: 70 IIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLV 129
I+++ +L+ L K+ RE+ I+K+++HP+++KL V E +K LYLV+E+ SGGE+FDYLV
Sbjct: 1 IVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLV 60
Query: 130 LHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTP 189
GR+ KEAR FRQIVSA+ +CH I HRDLK ENLLLD + NI+IADFG ++
Sbjct: 61 KKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVG 120
Query: 190 GAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERV 249
+ L+T CGSP YA PE+ +G+KYDG D+WS GVIL+ L+ G+LPFD LR+L E+V
Sbjct: 121 DSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKV 180
Query: 250 LRGKYRIPFYMSTDCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEP 306
RG + +P ++ DC++LL+ + + P KR SLE I + W G E + P +EP
Sbjct: 181 KRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPD--PCLEP 235
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 240 bits (587), Expect = 1e-62
Identities = 111/230 (48%), Positives = 162/230 (70%), Gaps = 2/230 (0%)
Query: 38 GKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHP 97
G Y L KT+G+G+FA VKLA+HV TG++VA+K+IDKT+L+ + LF+EVR MK++ HP
Sbjct: 14 GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHP 73
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGR-MKEKEARAKFRQIVSAVQYCHQK 156
NIV+L++VI+T+ LYL++E GG++FDY++ H + E A+ F QIV A+ YCH+
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133
Query: 157 RIIHRDLKAENLL-LDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
++HRDLK EN++ + + +K+ DFGFSN+F PG KL T CGS Y+APE+ G +YD
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCE 265
P VD+WSLGVIL+ LV PF + E ++ KY +P ++S +C+
Sbjct: 194 PAVDIWSLGVILFMLVCEQPPFQEANDSETLTMIMDCKYTVPSHVSKECK 243
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 226 bits (552), Expect = 2e-58
Identities = 104/207 (50%), Positives = 145/207 (70%)
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
+++HP+++KL V E +K LYLV+E+ SGGE+FDYLV GR+ KEAR FRQI+SA+ +
Sbjct: 1 LIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDF 60
Query: 153 CHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKK 212
CH I HRDLK ENLLLD + NI+IADFG ++ + L+T CGSP YA PE+ +G+K
Sbjct: 61 CHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEK 120
Query: 213 YDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFL 272
YDG + DVWS GVIL+ L+ G+LPFD LR+L E+V RG + +P ++ DC++LL+
Sbjct: 121 YDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMS 180
Query: 273 VLNPAKRASLESIMRDKWMNTGYEEDE 299
++ A+R +LE I + W G E E
Sbjct: 181 EVDAARRLTLEHIQKHIWYIGGKNEPE 207
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 216 bits (528), Expect = 2e-55
Identities = 121/328 (36%), Positives = 190/328 (57%), Gaps = 14/328 (4%)
Query: 37 IGKYKL-LKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSL--QKLFREVRIMKM 93
+G Y + + +G+G+FAKV+ HV TG++VAIK+IDK + + + L RE +I +M
Sbjct: 58 VGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQM 117
Query: 94 LDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYC 153
+ HPNI +L ++ETE + YLVME GG + + R++E EAR RQ++SAV++
Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHL 177
Query: 154 HQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTF---CGSPPYAAPELFQG 210
H+ ++HRDLK ENLLLD + NIK+ DFG SN D F CGSP YAAPEL
Sbjct: 178 HRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLAR 237
Query: 211 KKYDGPEVDVWSLGVILYTLVSGSLPF--DGSTLRELRERVLRGKYR-IPFYMSTDCENL 267
KKY GP++DVWS+GV +Y +++G+LPF + +LR L ++++ + +P +ST +
Sbjct: 238 KKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISF 296
Query: 268 LKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQ----QDFKDHKRIEALVCLG 323
L+ L +P KR +++ + ++W+N Y P +D + LG
Sbjct: 297 LRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLG 356
Query: 324 YNRQEIEYSLAEAKYDDVFATYLLLGRK 351
Y ++ ++ + + A Y LL +K
Sbjct: 357 YKNSDVINTVLSNRACHILAIYFLLNKK 384
>BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein.
Length = 185
Score = 207 bits (505), Expect = 1e-52
Identities = 97/143 (67%), Positives = 122/143 (85%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDH 96
IG Y++ +TIGKGNFA VK A H+ T +VAIKIIDKTQL+ +L+K+FREV+IMKML H
Sbjct: 27 IGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCH 86
Query: 97 PNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQK 156
P+I++L+QV+ETE+ +YLV EYASGGE+FD+LV HGRM EKEAR KF+QIV+AV +CH +
Sbjct: 87 PHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCR 146
Query: 157 RIIHRDLKAENLLLDGEMNIKIA 179
I+HRDLKAENLLLD +NIKIA
Sbjct: 147 NIVHRDLKAENLLLDANLNIKIA 169
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 202 bits (492), Expect = 4e-51
Identities = 91/174 (52%), Positives = 126/174 (72%), Gaps = 1/174 (0%)
Query: 49 GNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLDHPNIVKLFQVIE 107
G F KVK+ KH TG +VA+KI+++ ++ + K+ RE++ +K+ HP+I+KL+QVI
Sbjct: 1 GAFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVIS 60
Query: 108 TEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDLKAEN 167
T +++VMEY SGGE+FDY+ +GR+ EKE+R F+QI+S V YCH+ ++HRDLK EN
Sbjct: 61 TPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPEN 120
Query: 168 LLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 221
+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+ Y GPEVD+W
Sbjct: 121 VLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYVGPEVDLW 174
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 198 bits (484), Expect = 4e-50
Identities = 104/257 (40%), Positives = 162/257 (63%), Gaps = 6/257 (2%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
Y+L KTIG+G ++KVK A ++VAIK+IDK +Q+ RE++I++ LDH N
Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69
Query: 99 IVKLFQVIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
I+++++++E+ + + LVME A GG+VFD ++ G + E A+A FRQ+V A++YCH
Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK--LDTFCGSPPYAAPELFQGKKYDG 215
+ HRDLK EN LL G N+K+ DFGF+ + TFCGS YAAPE+ QG +D
Sbjct: 130 VAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDS 188
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG-KYRIPFYMSTDCENLLKKFLVL 274
+ DVWS+GV+LY ++ SLPFD + + ++ + +G + +S DC++LLK+ L
Sbjct: 189 KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEP 248
Query: 275 NPAKRASLESIMRDKWM 291
+ R S+E + W+
Sbjct: 249 DMILRPSIEEVSWHPWL 265
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 198 bits (484), Expect = 4e-50
Identities = 104/257 (40%), Positives = 162/257 (63%), Gaps = 6/257 (2%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
Y+L KTIG+G ++KVK A ++VAIK+IDK +Q+ RE++I++ LDH N
Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69
Query: 99 IVKLFQVIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
I+++++++E+ + + LVME A GG+VFD ++ G + E A+A FRQ+V A++YCH
Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK--LDTFCGSPPYAAPELFQGKKYDG 215
+ HRDLK EN LL G N+K+ DFGF+ + TFCGS YAAPE+ QG +D
Sbjct: 130 VAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDS 188
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG-KYRIPFYMSTDCENLLKKFLVL 274
+ DVWS+GV+LY ++ SLPFD + + ++ + +G + +S DC++LLK+ L
Sbjct: 189 KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEP 248
Query: 275 NPAKRASLESIMRDKWM 291
+ R S+E + W+
Sbjct: 249 DMILRPSIEEVSWHPWL 265
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 198 bits (484), Expect = 4e-50
Identities = 104/257 (40%), Positives = 162/257 (63%), Gaps = 6/257 (2%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
Y+L KTIG+G ++KVK A ++VAIK+IDK +Q+ RE++I++ LDH N
Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69
Query: 99 IVKLFQVIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
I+++++++E+ + + LVME A GG+VFD ++ G + E A+A FRQ+V A++YCH
Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK--LDTFCGSPPYAAPELFQGKKYDG 215
+ HRDLK EN LL G N+K+ DFGF+ + TFCGS YAAPE+ QG +D
Sbjct: 130 VAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDS 188
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG-KYRIPFYMSTDCENLLKKFLVL 274
+ DVWS+GV+LY ++ SLPFD + + ++ + +G + +S DC++LLK+ L
Sbjct: 189 KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEP 248
Query: 275 NPAKRASLESIMRDKWM 291
+ R S+E + W+
Sbjct: 249 DMILRPSIEEVSWHPWL 265
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 198 bits (484), Expect = 4e-50
Identities = 104/257 (40%), Positives = 162/257 (63%), Gaps = 6/257 (2%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
Y+L KTIG+G ++KVK A ++VAIK+IDK +Q+ RE++I++ LDH N
Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69
Query: 99 IVKLFQVIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
I+++++++E+ + + LVME A GG+VFD ++ G + E A+A FRQ+V A++YCH
Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK--LDTFCGSPPYAAPELFQGKKYDG 215
+ HRDLK EN LL G N+K+ DFGF+ + TFCGS YAAPE+ QG +D
Sbjct: 130 VAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDS 188
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG-KYRIPFYMSTDCENLLKKFLVL 274
+ DVWS+GV+LY ++ SLPFD + + ++ + +G + +S DC++LLK+ L
Sbjct: 189 KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEP 248
Query: 275 NPAKRASLESIMRDKWM 291
+ R S+E + W+
Sbjct: 249 DMILRPSIEEVSWHPWL 265
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 195 bits (475), Expect = 5e-49
Identities = 90/176 (51%), Positives = 125/176 (71%), Gaps = 1/176 (0%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNP-GSLQKLFREVRIMKMLD 95
IG Y L T+G G F KVK+ KH TG +VA+KI+++ ++ + K+ RE++ +K+
Sbjct: 15 IGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFR 74
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I+KL+QVI T +++VMEY SGGE+FDY+ +GR+ EKE+R F+QI+S V YCH+
Sbjct: 75 HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 134
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
++HRDLK EN+LLD MN KIADFG SN + G L T CGSP YAAPE+ G+
Sbjct: 135 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGR 190
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 192 bits (467), Expect = 4e-48
Identities = 102/263 (38%), Positives = 161/263 (61%), Gaps = 13/263 (4%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
Y L +G+G++AKVK A VAIKIID+ + L+K RE+ I+ ML+H +
Sbjct: 12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCS 71
Query: 99 IVKLFQVIETEK-TLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
I+K +++ ET +Y+VME A G++ + + G + E EAR KF Q+ A++YCH
Sbjct: 72 IIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFS-----NEFTPGAKLDTFCGSPPYAAPELFQGKK 212
++HRDLK +NLLLD + NIK++DF FS ++ A TFCGSP YAAPE+ QG
Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191
Query: 213 YDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLL 268
Y D+WSLGVILY +V GS+P+D S ++++ ++ ++R+ F +++ +C++L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLR--IQKEHRVNFPRSKHLTGECKDLI 249
Query: 269 KKFLVLNPAKRASLESIMRDKWM 291
L + +R ++ I+ WM
Sbjct: 250 YHMLQPDVNRRLHIDEILSHCWM 272
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 192 bits (467), Expect = 4e-48
Identities = 102/263 (38%), Positives = 161/263 (61%), Gaps = 13/263 (4%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
Y L +G+G++AKVK A VAIKIID+ + L+K RE+ I+ ML+H +
Sbjct: 12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCS 71
Query: 99 IVKLFQVIETEK-TLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
I+K +++ ET +Y+VME A G++ + + G + E EAR KF Q+ A++YCH
Sbjct: 72 IIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFS-----NEFTPGAKLDTFCGSPPYAAPELFQGKK 212
++HRDLK +NLLLD + NIK++DF FS ++ A TFCGSP YAAPE+ QG
Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191
Query: 213 YDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLL 268
Y D+WSLGVILY +V GS+P+D S ++++ ++ ++R+ F +++ +C++L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLR--IQKEHRVNFPRSKHLTGECKDLI 249
Query: 269 KKFLVLNPAKRASLESIMRDKWM 291
L + +R ++ I+ WM
Sbjct: 250 YHMLQPDVNRRLHIDEILSHCWM 272
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 192 bits (467), Expect = 4e-48
Identities = 102/263 (38%), Positives = 161/263 (61%), Gaps = 13/263 (4%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
Y L +G+G++AKVK A VAIKIID+ + L+K RE+ I+ ML+H +
Sbjct: 12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCS 71
Query: 99 IVKLFQVIETEK-TLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
I+K +++ ET +Y+VME A G++ + + G + E EAR KF Q+ A++YCH
Sbjct: 72 IIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFS-----NEFTPGAKLDTFCGSPPYAAPELFQGKK 212
++HRDLK +NLLLD + NIK++DF FS ++ A TFCGSP YAAPE+ QG
Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191
Query: 213 YDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLL 268
Y D+WSLGVILY +V GS+P+D S ++++ ++ ++R+ F +++ +C++L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLR--IQKEHRVNFPRSKHLTGECKDLI 249
Query: 269 KKFLVLNPAKRASLESIMRDKWM 291
L + +R ++ I+ WM
Sbjct: 250 YHMLQPDVNRRLHIDEILSHCWM 272
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 186 bits (454), Expect = 2e-46
Identities = 103/259 (39%), Positives = 151/259 (58%), Gaps = 4/259 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLD 95
I +K+ +GKG+FA V A+ + TG EVAIK+IDK + G +Q++ EV+I L
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLK 68
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGR-MKEKEARAKFRQIVSAVQYCH 154
HP+I++L+ E +YLV+E GE+ YL + E EAR QI++ + Y H
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFT-PGAKLDTFCGSPPYAAPELFQGKKY 213
I+HRDL NLLL MNIKIADFG + + P K T CG+P Y +PE+ +
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
G E DVWSLG + YTL+ G PFD T++ +V+ Y +P ++S + ++L+ + L
Sbjct: 189 -GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLR 247
Query: 274 LNPAKRASLESIMRDKWMN 292
NPA R SL S++ +M+
Sbjct: 248 RNPADRLSLSSVLDHPFMS 266
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 186 bits (454), Expect = 2e-46
Identities = 103/259 (39%), Positives = 151/259 (58%), Gaps = 4/259 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLD 95
I +K+ +GKG+FA V A+ + TG EVAIK+IDK + G +Q++ EV+I L
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGR-MKEKEARAKFRQIVSAVQYCH 154
HP+I++L+ E +YLV+E GE+ YL + E EAR QI++ + Y H
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFT-PGAKLDTFCGSPPYAAPELFQGKKY 213
I+HRDL NLLL MNIKIADFG + + P K T CG+P Y +PE+ +
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
G E DVWSLG + YTL+ G PFD T++ +V+ Y +P ++S + ++L+ + L
Sbjct: 189 -GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLR 247
Query: 274 LNPAKRASLESIMRDKWMN 292
NPA R SL S++ +M+
Sbjct: 248 RNPADRLSLSSVLDHPFMS 266
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 185 bits (450), Expect = 5e-46
Identities = 95/257 (36%), Positives = 157/257 (61%), Gaps = 13/257 (5%)
Query: 46 IGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPNIVKLFQ 104
+GKG++AKVK A VA+KIID+ + +++ RE+ I+ ++H +I+K ++
Sbjct: 18 LGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYE 77
Query: 105 VIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDL 163
+ ET + +Y++ME G++ +++ G + E AR FRQ+ SAV+YCH I+HRDL
Sbjct: 78 IFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDL 137
Query: 164 KAENLLLDGEMNIKIADFGFSNEFTPGAK-----LDTFCGSPPYAAPELFQGKKYDGPEV 218
K ENLLLD + NIK++DFGFS + TFCGS YAAPE+ Q Y
Sbjct: 138 KCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVY 197
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKFLVL 274
D+WSLGVILY +V GS+P+D S +R++ ++ ++R+ F ++ +C++L+ + L
Sbjct: 198 DIWSLGVILYIMVCGSMPYDDSDIRKMLR--IQKEHRVDFPRSKNLTCECKDLIYRMLQP 255
Query: 275 NPAKRASLESIMRDKWM 291
+ ++R ++ I+ W+
Sbjct: 256 DVSQRLHIDEILSHSWL 272
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 185 bits (450), Expect = 5e-46
Identities = 95/257 (36%), Positives = 157/257 (61%), Gaps = 13/257 (5%)
Query: 46 IGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPNIVKLFQ 104
+GKG++AKVK A VA+KIID+ + +++ RE+ I+ ++H +I+K ++
Sbjct: 18 LGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYE 77
Query: 105 VIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDL 163
+ ET + +Y++ME G++ +++ G + E AR FRQ+ SAV+YCH I+HRDL
Sbjct: 78 IFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDL 137
Query: 164 KAENLLLDGEMNIKIADFGFSNEFTPGAK-----LDTFCGSPPYAAPELFQGKKYDGPEV 218
K ENLLLD + NIK++DFGFS + TFCGS YAAPE+ Q Y
Sbjct: 138 KCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVY 197
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKFLVL 274
D+WSLGVILY +V GS+P+D S +R++ ++ ++R+ F ++ +C++L+ + L
Sbjct: 198 DIWSLGVILYIMVCGSMPYDDSDIRKMLR--IQKEHRVDFPRSKNLTCECKDLIYRMLQP 255
Query: 275 NPAKRASLESIMRDKWM 291
+ ++R ++ I+ W+
Sbjct: 256 DVSQRLHIDEILSHSWL 272
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 185 bits (450), Expect = 5e-46
Identities = 95/257 (36%), Positives = 157/257 (61%), Gaps = 13/257 (5%)
Query: 46 IGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPNIVKLFQ 104
+GKG++AKVK A VA+KIID+ + +++ RE+ I+ ++H +I+K ++
Sbjct: 18 LGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYE 77
Query: 105 VIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDL 163
+ ET + +Y++ME G++ +++ G + E AR FRQ+ SAV+YCH I+HRDL
Sbjct: 78 IFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDL 137
Query: 164 KAENLLLDGEMNIKIADFGFSNEFTPGAK-----LDTFCGSPPYAAPELFQGKKYDGPEV 218
K ENLLLD + NIK++DFGFS + TFCGS YAAPE+ Q Y
Sbjct: 138 KCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVY 197
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKFLVL 274
D+WSLGVILY +V GS+P+D S +R++ ++ ++R+ F ++ +C++L+ + L
Sbjct: 198 DIWSLGVILYIMVCGSMPYDDSDIRKMLR--IQKEHRVDFPRSKNLTCECKDLIYRMLQP 255
Query: 275 NPAKRASLESIMRDKWM 291
+ ++R ++ I+ W+
Sbjct: 256 DVSQRLHIDEILSHSWL 272
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 185 bits (450), Expect = 5e-46
Identities = 95/257 (36%), Positives = 157/257 (61%), Gaps = 13/257 (5%)
Query: 46 IGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPNIVKLFQ 104
+GKG++AKVK A VA+KIID+ + +++ RE+ I+ ++H +I+K ++
Sbjct: 18 LGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYE 77
Query: 105 VIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDL 163
+ ET + +Y++ME G++ +++ G + E AR FRQ+ SAV+YCH I+HRDL
Sbjct: 78 IFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDL 137
Query: 164 KAENLLLDGEMNIKIADFGFSNEFTPGAK-----LDTFCGSPPYAAPELFQGKKYDGPEV 218
K ENLLLD + NIK++DFGFS + TFCGS YAAPE+ Q Y
Sbjct: 138 KCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVY 197
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKFLVL 274
D+WSLGVILY +V GS+P+D S +R++ ++ ++R+ F ++ +C++L+ + L
Sbjct: 198 DIWSLGVILYIMVCGSMPYDDSDIRKMLR--IQKEHRVDFPRSKNLTCECKDLIYRMLQP 255
Query: 275 NPAKRASLESIMRDKWM 291
+ ++R ++ I+ W+
Sbjct: 256 DVSQRLHIDEILSHSWL 272
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 185 bits (450), Expect = 5e-46
Identities = 102/259 (39%), Positives = 151/259 (58%), Gaps = 4/259 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLD 95
I +K+ +GKG+FA V A+ + +G EVAIK+IDK + G +Q++ EV+I L
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGR-MKEKEARAKFRQIVSAVQYCH 154
HP+I++L+ E +YLV+E GE+ YL + E EAR QI++ + Y H
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFT-PGAKLDTFCGSPPYAAPELFQGKKY 213
I+HRDL NLLL MNIKIADFG + + P K T CG+P Y +PE+ +
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
G E DVWSLG + YTL+ G PFD T++ +V+ Y +P ++S + ++L+ + L
Sbjct: 189 -GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLR 247
Query: 274 LNPAKRASLESIMRDKWMN 292
NPA R SL S++ +M+
Sbjct: 248 RNPADRLSLSSVLDHPFMS 266
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 183 bits (446), Expect = 2e-45
Identities = 101/260 (38%), Positives = 153/260 (58%), Gaps = 6/260 (2%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
YKL +TIG+G+++KVK+A VAIK++D+ + P + K RE+ I++ + HP+
Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71
Query: 99 IVKLFQVIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
IV +F+ IE LY+VME A+ ++ + +GR+ +AR F QI AV+Y H
Sbjct: 72 IVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHH 130
Query: 158 IIHRDLKAENLLLD-GEMNIKIADFGFSNEFTPGAKLDT-FCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LL E +K+ DFGF + L T +CGS YA+PE+ G YD
Sbjct: 131 LVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDP 190
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG-KYRIPFYMSTDCENLLKKFLVL 274
+ DVWS+GV+LY +V+G +PFD S + L R RG Y +S C+ L+ + L
Sbjct: 191 KKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQF 250
Query: 275 NPAKRASLESIMRDKWMNTG 294
+P+ R S + R+ W+ G
Sbjct: 251 SPSARPSAGQVARNCWLRAG 270
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 183 bits (446), Expect = 2e-45
Identities = 101/260 (38%), Positives = 153/260 (58%), Gaps = 6/260 (2%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
YKL +TIG+G+++KVK+A VAIK++D+ + P + K RE+ I++ + HP+
Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71
Query: 99 IVKLFQVIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
IV +F+ IE LY+VME A+ ++ + +GR+ +AR F QI AV+Y H
Sbjct: 72 IVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHH 130
Query: 158 IIHRDLKAENLLLD-GEMNIKIADFGFSNEFTPGAKLDT-FCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LL E +K+ DFGF + L T +CGS YA+PE+ G YD
Sbjct: 131 LVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDP 190
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG-KYRIPFYMSTDCENLLKKFLVL 274
+ DVWS+GV+LY +V+G +PFD S + L R RG Y +S C+ L+ + L
Sbjct: 191 KKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQF 250
Query: 275 NPAKRASLESIMRDKWMNTG 294
+P+ R S + R+ W+ G
Sbjct: 251 SPSARPSAGQVARNCWLRAG 270
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 180 bits (439), Expect = 1e-44
Identities = 88/253 (34%), Positives = 148/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 132 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 191
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ + +I +A+ YCH KR+
Sbjct: 192 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRIANALSYCHSKRV 251
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 252 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 309
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 310 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 369
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 370 RPMLREVLEHPWI 382
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 179 bits (436), Expect = 2e-44
Identities = 96/264 (36%), Positives = 149/264 (56%), Gaps = 9/264 (3%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKML 94
H+ +++ +KT+G G+F +V L KH TG A+KI+DK ++ ++ E RI++ +
Sbjct: 40 HLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+ P +VKL + LY+VMEY GGE+F +L GR E AR QIV +Y H
Sbjct: 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+I+RDLK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN 217
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
VD W+LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L +
Sbjct: 218 -KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 275 NPAKR-----ASLESIMRDKWMNT 293
+ KR + I KW T
Sbjct: 277 DLTKRFGNLKNGVNDIKNHKWFAT 300
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 179 bits (436), Expect = 2e-44
Identities = 96/264 (36%), Positives = 149/264 (56%), Gaps = 9/264 (3%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKML 94
H+ +++ +KT+G G+F +V L KH TG A+KI+DK ++ ++ E RI++ +
Sbjct: 40 HLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+ P +VKL + LY+VMEY GGE+F +L GR E AR QIV +Y H
Sbjct: 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+I+RDLK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN 217
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
VD W+LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L +
Sbjct: 218 -KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 275 NPAKR-----ASLESIMRDKWMNT 293
+ KR + I KW T
Sbjct: 277 DLTKRFGNLKNGVNDIKNHKWFAT 300
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 179 bits (436), Expect = 2e-44
Identities = 96/264 (36%), Positives = 149/264 (56%), Gaps = 9/264 (3%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKML 94
H+ +++ +KT+G G+F +V L KH TG A+KI+DK ++ ++ E RI++ +
Sbjct: 40 HLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+ P +VKL + LY+VMEY GGE+F +L GR E AR QIV +Y H
Sbjct: 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+I+RDLK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN 217
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
VD W+LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L +
Sbjct: 218 -KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 275 NPAKR-----ASLESIMRDKWMNT 293
+ KR + I KW T
Sbjct: 277 DLTKRFGNLKNGVNDIKNHKWFAT 300
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 179 bits (436), Expect = 2e-44
Identities = 88/256 (34%), Positives = 146/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
+ +++ + +GKG F V LA+ + VA+K++ K+Q+ L+ +L RE+ I L
Sbjct: 6 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 65
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L ++ E+ ++ A+ YCH
Sbjct: 66 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 125
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL +KIADFG+S TP + T CG+ Y PE+ +G+ YD
Sbjct: 126 KKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD- 183
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G PF+ ++ E R+L+ R P M +L+ + L
Sbjct: 184 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 243
Query: 276 PAKRASLESIMRDKWM 291
P +R L I++ W+
Sbjct: 244 PLERLPLAQILKHPWV 259
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 179 bits (436), Expect = 2e-44
Identities = 96/264 (36%), Positives = 149/264 (56%), Gaps = 9/264 (3%)
Query: 36 HIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKML 94
H+ +++ +KT+G G+F +V L KH TG A+KI+DK ++ ++ E RI++ +
Sbjct: 40 HLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+ P +VKL + LY+VMEY GGE+F +L GR E AR QIV +Y H
Sbjct: 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+I+RDLK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN 217
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVL 274
VD W+LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L +
Sbjct: 218 -KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276
Query: 275 NPAKR-----ASLESIMRDKWMNT 293
+ KR + I KW T
Sbjct: 277 DLTKRFGNLKNGVNDIKNHKWFAT 300
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 179 bits (436), Expect = 2e-44
Identities = 87/253 (34%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH KR+
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 371 RPMLREVLEHPWI 383
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 179 bits (436), Expect = 2e-44
Identities = 87/253 (34%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH KR+
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 371 RPMLREVLEHPWI 383
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 179 bits (436), Expect = 2e-44
Identities = 87/253 (34%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH KR+
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 371 RPMLREVLEHPWI 383
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 179 bits (436), Expect = 2e-44
Identities = 87/253 (34%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH KR+
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 371 RPMLREVLEHPWI 383
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 179 bits (436), Expect = 2e-44
Identities = 88/256 (34%), Positives = 146/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
+ +++ + +GKG F V LA+ + VA+K++ K+Q+ L+ +L RE+ I L
Sbjct: 37 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 96
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L ++ E+ ++ A+ YCH
Sbjct: 97 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 156
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL +KIADFG+S TP + T CG+ Y PE+ +G+ YD
Sbjct: 157 KKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD- 214
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G PF+ ++ E R+L+ R P M +L+ + L
Sbjct: 215 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 274
Query: 276 PAKRASLESIMRDKWM 291
P +R L I++ W+
Sbjct: 275 PLERLPLAQILKHPWV 290
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 179 bits (436), Expect = 2e-44
Identities = 88/256 (34%), Positives = 146/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
+ +++ + +GKG F V LA+ + VA+K++ K+Q+ L+ +L RE+ I L
Sbjct: 21 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 80
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L ++ E+ ++ A+ YCH
Sbjct: 81 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 140
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL +KIADFG+S TP + T CG+ Y PE+ +G+ YD
Sbjct: 141 KKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD- 198
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G PF+ ++ E R+L+ R P M +L+ + L
Sbjct: 199 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 258
Query: 276 PAKRASLESIMRDKWM 291
P +R L I++ W+
Sbjct: 259 PLERLPLAQILKHPWV 274
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 179 bits (436), Expect = 2e-44
Identities = 87/253 (34%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH KR+
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 371 RPMLREVLEHPWI 383
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 179 bits (436), Expect = 2e-44
Identities = 87/253 (34%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH KR+
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 371 RPMLREVLEHPWI 383
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 179 bits (436), Expect = 2e-44
Identities = 87/253 (34%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH KR+
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 371 RPMLREVLEHPWI 383
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 179 bits (436), Expect = 2e-44
Identities = 87/253 (34%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLDHPN 98
+++ + +GKG F V LA+ + +A+K++ K QL ++ +L REV I L HPN
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH KR+
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEV 218
IHRD+K ENLLL +KIADFG+S P ++ T CG+ Y PE+ +G+ +D +V
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
Query: 219 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAK 278
D+WSLGV+ Y + G PF+ +T +E +R+ R ++ P +++ +L+ + L NP++
Sbjct: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
Query: 279 RASLESIMRDKWM 291
R L ++ W+
Sbjct: 371 RPMLREVLEHPWI 383
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 179 bits (436), Expect = 2e-44
Identities = 88/256 (34%), Positives = 146/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
+ +++ + +GKG F V LA+ + VA+K++ K+Q+ L+ +L RE+ I L
Sbjct: 40 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 99
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L ++ E+ ++ A+ YCH
Sbjct: 100 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 159
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL +KIADFG+S TP + T CG+ Y PE+ +G+ YD
Sbjct: 160 KKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD- 217
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G PF+ ++ E R+L+ R P M +L+ + L
Sbjct: 218 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 277
Query: 276 PAKRASLESIMRDKWM 291
P +R L I++ W+
Sbjct: 278 PLERLPLAQILKHPWV 293
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 178 bits (434), Expect = 4e-44
Identities = 88/256 (34%), Positives = 146/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
+ +++ + +GKG F V LA+ + VA+K++ K+Q+ L+ +L RE+ I L
Sbjct: 40 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 99
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L ++ E+ ++ A+ YCH
Sbjct: 100 HPNILRLYNHFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 159
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL +KIADFG+S TP + T CG+ Y PE+ +G+ YD
Sbjct: 160 KKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYD- 217
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G PF+ ++ E R+L+ R P M +L+ + L
Sbjct: 218 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 277
Query: 276 PAKRASLESIMRDKWM 291
P +R L I++ W+
Sbjct: 278 PLERLPLAQILKHPWV 293
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 178 bits (433), Expect = 6e-44
Identities = 98/261 (37%), Positives = 149/261 (57%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ +PTG+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 192 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITASEALKHPWI 272
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 177 bits (432), Expect = 8e-44
Identities = 88/256 (34%), Positives = 146/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
+ +++ + +GKG F V LA+ + VA+K++ K+Q+ L+ +L RE+ I L
Sbjct: 6 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 65
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L ++ E+ ++ A+ YCH
Sbjct: 66 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHD 125
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL +KIADFG+S TP + T CG+ Y PE+ +G+ YD
Sbjct: 126 KKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPLPERKTMCGTLDYLPPEMIEGRTYD- 183
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G PF+ ++ E R+L+ R P M +L+ + L
Sbjct: 184 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 243
Query: 276 PAKRASLESIMRDKWM 291
P +R L I++ W+
Sbjct: 244 PLERLPLAQILKHPWV 259
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 175 bits (427), Expect = 3e-43
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ +PTG+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ +V +CH I
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 192 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITASEALKHPWI 272
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 175 bits (427), Expect = 3e-43
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ +PTG+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 43 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 102
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ +V +CH I
Sbjct: 103 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 162
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 163 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY- 221
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 222 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 281
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 282 MLTINPAKRITASEALKHPWI 302
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 175 bits (426), Expect = 4e-43
Identities = 97/260 (37%), Positives = 147/260 (56%), Gaps = 9/260 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ +PTG+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ +V +CH I
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 192 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 251
Query: 271 FLVLNPAKRASLESIMRDKW 290
L +NPAKR + ++ W
Sbjct: 252 MLTINPAKRITASEALKHPW 271
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 174 bits (424), Expect = 7e-43
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
++ +T+G G F++V LA+ TGK A+K I K L G + E+ +++ + H NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK-GKESSIENEIAVLRKIKHENI 81
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYLVM+ SGGE+FD +V G EK+A RQ++ AV Y H+ I+
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 160 HRDLKAENLLL---DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL D E I I+DFG S G + T CG+P Y APE+ K Y
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPY-SK 200
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E R W+
Sbjct: 261 EKDPNKRYTCEQAARHPWI 279
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 174 bits (424), Expect = 7e-43
Identities = 105/292 (35%), Positives = 163/292 (55%), Gaps = 19/292 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+ + IG GNFA VK +H T + A+KIIDK++L G + E+ I++ L HPNI
Sbjct: 316 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLK-GKEDMVDSEILIIQSLSHPNI 374
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
VKL +V ET+ +YL++EY GG++FD ++ + E +A + A+ + H K I+
Sbjct: 375 VKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIV 434
Query: 160 HRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
HRDLK ENLL+ D +K+ADFG + + T CG+P Y APE+ K Y G
Sbjct: 435 HRDLKPENLLVQRNEDKSTTLKLADFGLAKHVV--RPIFTVCGTPTYVAPEILSEKGY-G 491
Query: 216 PEVDVWSLGVILYTLVSGSLPFDG--STLRELRERVLRGKYR-IPFY---MSTDCENLLK 269
EVD+W+ GVILY L+ G PF EL + G + +P Y +S ++L+
Sbjct: 492 LEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVS 551
Query: 270 KFLVLNPAKRASLESIMRDKWMNTGYEEDELR--PYVEPQQD--FK-DHKRI 316
+ LV++P KR + +++ W+ T + + ++ V P + F+ HKR+
Sbjct: 552 RLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRV 603
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 173 bits (420), Expect = 2e-42
Identities = 91/242 (37%), Positives = 142/242 (58%), Gaps = 4/242 (1%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 97
+++ L+T+G G+F +V L +H TG A+KI++K ++ ++ + E RI++ +D P
Sbjct: 52 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 111
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
+VKL + LYLVMEY GGE+F L GR E A Q+V AVQY H
Sbjct: 112 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 171
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
+IHRDLK ENLL+D + +++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 172 LIHRDLKPENLLIDQQGYLQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KA 228
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W+LGV++Y + G PF ++ E+++ G+ R P +S+D ++LL+ L ++
Sbjct: 229 VDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKDLLRSLLQVDLT 288
Query: 278 KR 279
KR
Sbjct: 289 KR 290
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 173 bits (420), Expect = 2e-42
Identities = 91/242 (37%), Positives = 142/242 (58%), Gaps = 4/242 (1%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 97
+++ L+T+G G+F +V L +H TG A+KI++K ++ ++ + E RI++ +D P
Sbjct: 43 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 102
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
+VKL + LYLVMEY GGE+F L GR E A Q+V AVQY H
Sbjct: 103 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 162
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
+IHRDLK ENLL+D + +++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 163 LIHRDLKPENLLIDQQGYLQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KA 219
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W+LGV++Y + G PF ++ E+++ G+ R P +S+D ++LL+ L ++
Sbjct: 220 VDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLT 279
Query: 278 KR 279
KR
Sbjct: 280 KR 281
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 173 bits (420), Expect = 2e-42
Identities = 91/242 (37%), Positives = 142/242 (58%), Gaps = 4/242 (1%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 97
+++ L+T+G G+F +V L +H TG A+KI++K ++ ++ + E RI++ +D P
Sbjct: 43 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 102
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
+VKL + LYLVMEY GGE+F L GR E A Q+V AVQY H
Sbjct: 103 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 162
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
+IHRDLK ENLL+D + +++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 163 LIHRDLKPENLLIDQQGYLQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KA 219
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W+LGV++Y + G PF ++ E+++ G+ R P +S+D ++LL+ L ++
Sbjct: 220 VDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLT 279
Query: 278 KR 279
KR
Sbjct: 280 KR 281
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 173 bits (420), Expect = 2e-42
Identities = 91/242 (37%), Positives = 142/242 (58%), Gaps = 4/242 (1%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 97
+++ L+T+G G+F +V L +H TG A+KI++K ++ ++ + E RI++ +D P
Sbjct: 43 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 102
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
+VKL + LYLVMEY GGE+F L GR E A Q+V AVQY H
Sbjct: 103 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 162
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
+IHRDLK ENLL+D + +++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 163 LIHRDLKPENLLIDQQGYLQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KA 219
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W+LGV++Y + G PF ++ E+++ G+ R P +S+D ++LL+ L ++
Sbjct: 220 VDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLT 279
Query: 278 KR 279
KR
Sbjct: 280 KR 281
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 173 bits (420), Expect = 2e-42
Identities = 91/242 (37%), Positives = 142/242 (58%), Gaps = 4/242 (1%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHP 97
+++ L+T+G G+F +V L +H TG A+KI++K ++ ++ + E RI++ +D P
Sbjct: 43 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 102
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
+VKL + LYLVMEY GGE+F L GR E A Q+V AVQY H
Sbjct: 103 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 162
Query: 158 IIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
+IHRDLK ENLL+D + +++ DFGF+ + T CG+P Y APE+ K Y+
Sbjct: 163 LIHRDLKPENLLIDQQGYLQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KA 219
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W+LGV++Y + G PF ++ E+++ G+ R P +S+D ++LL+ L ++
Sbjct: 220 VDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLT 279
Query: 278 KR 279
KR
Sbjct: 280 KR 281
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 173 bits (420), Expect = 2e-42
Identities = 96/261 (36%), Positives = 147/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ +PTG+ A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ +V +CH I
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 192 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITASEALKHPWI 272
>X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase
protein.
Length = 387
Score = 172 bits (419), Expect = 3e-42
Identities = 103/289 (35%), Positives = 159/289 (55%), Gaps = 19/289 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQ 151
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++ +
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139
Query: 152 YCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+ +
Sbjct: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199
Query: 212 KYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MST 262
+ G EVD+WS GVI+YTL++GS PF + ++ G Y+ P + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 306
>BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 172 bits (419), Expect = 3e-42
Identities = 103/289 (35%), Positives = 159/289 (55%), Gaps = 19/289 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQ 151
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++ +
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139
Query: 152 YCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+ +
Sbjct: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199
Query: 212 KYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MST 262
+ G EVD+WS GVI+YTL++GS PF + ++ G Y+ P + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 306
>BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 172 bits (419), Expect = 3e-42
Identities = 103/289 (35%), Positives = 159/289 (55%), Gaps = 19/289 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQ 151
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++ +
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139
Query: 152 YCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+ +
Sbjct: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199
Query: 212 KYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MST 262
+ G EVD+WS GVI+YTL++GS PF + ++ G Y+ P + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 306
>BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 172 bits (419), Expect = 3e-42
Identities = 103/289 (35%), Positives = 159/289 (55%), Gaps = 19/289 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQ 151
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++ +
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139
Query: 152 YCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+ +
Sbjct: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199
Query: 212 KYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MST 262
+ G EVD+WS GVI+YTL++GS PF + ++ G Y+ P + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 306
>BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 172 bits (419), Expect = 3e-42
Identities = 103/289 (35%), Positives = 159/289 (55%), Gaps = 19/289 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQ 151
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++ +
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139
Query: 152 YCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+ +
Sbjct: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199
Query: 212 KYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MST 262
+ G EVD+WS GVI+YTL++GS PF + ++ G Y+ P + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 306
>BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 172 bits (419), Expect = 3e-42
Identities = 103/289 (35%), Positives = 159/289 (55%), Gaps = 19/289 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQ 151
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++ +
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139
Query: 152 YCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+ +
Sbjct: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199
Query: 212 KYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MST 262
+ G EVD+WS GVI+YTL++GS PF + ++ G Y+ P + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 306
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 172 bits (419), Expect = 3e-42
Identities = 90/246 (36%), Positives = 139/246 (56%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQ-LNPGSLQKLFREVRIMKML- 94
I ++ ++ +GKG+F KV LA+ TG A+K++ K L ++ E RI+ +
Sbjct: 352 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLAR 411
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HP + +LF +T L+ VME+ +GG++ ++ R E AR +I+SA+ + H
Sbjct: 412 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 471
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
K II+RDLK +N+LLD E + K+ADFG E G TFCG+P Y APE+ Q Y
Sbjct: 472 DKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 531
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
GP VD W++GV+LY ++ G PF+ +L E +L + P ++ D +LK F+
Sbjct: 532 -GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMT 590
Query: 274 LNPAKR 279
NP R
Sbjct: 591 KNPTMR 596
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 172 bits (419), Expect = 3e-42
Identities = 96/246 (39%), Positives = 146/246 (59%), Gaps = 6/246 (2%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLF-REVRIMKMLDHPN 98
YKL +TIG+G+++KVK+A VAIK++D+ + P + K RE+ I++ + HP+
Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71
Query: 99 IVKLFQVIET-EKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
IV +F+ IE LY+VME A+ ++ + +GR+ +AR F QI AV+Y H
Sbjct: 72 IVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHH 130
Query: 158 IIHRDLKAENLLLD-GEMNIKIADFGFSNEFTPGAKLDT-FCGSPPYAAPELFQGKKYDG 215
++HRDLK EN+LL E +K+ DFGF + L T +CGS YA+PE+ G YD
Sbjct: 131 LVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDP 190
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG-KYRIPFYMSTDCENLLKKFLVL 274
+ DVWS+GV+LY +V+G +PFD S + L R RG Y +S C+ L+ + +
Sbjct: 191 KKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAEAAAV 250
Query: 275 NPAKRA 280
P ++A
Sbjct: 251 QPVRQA 256
>AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase gamma
protein.
Length = 387
Score = 172 bits (419), Expect = 3e-42
Identities = 103/289 (35%), Positives = 159/289 (55%), Gaps = 19/289 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQ 151
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++ +
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139
Query: 152 YCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+ +
Sbjct: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199
Query: 212 KYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MST 262
+ G EVD+WS GVI+YTL++GS PF + ++ G Y+ P + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 306
>AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein.
Length = 387
Score = 172 bits (419), Expect = 3e-42
Identities = 103/289 (35%), Positives = 159/289 (55%), Gaps = 19/289 (6%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQ 151
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++ +
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139
Query: 152 YCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGK 211
H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+ +
Sbjct: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199
Query: 212 KYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MST 262
+ G EVD+WS GVI+YTL++GS PF + ++ G Y+ P + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 306
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 172 bits (418), Expect = 4e-42
Identities = 97/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
P + + L++T+G+G + +V+LA + T + VA+KI+D + + + +E+ I KML
Sbjct: 4 PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA-VDCPENIKKEICINKML 62
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+H N+VK + YL +EY SGGE+FD + M E +A+ F Q+++ V Y H
Sbjct: 63 NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGK 211
I HRD+K ENLLLD N+KI+DFG + F + L+ CG+ PY APEL + +
Sbjct: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFD--GSTLRELRERVLRGKYRIPFYMSTDCE-NLL 268
++ VDVWS G++L +++G LP+D + +E + + Y P+ LL
Sbjct: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
Query: 269 KKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYV 304
K LV NP+ R ++ I +D+W N ++ RP V
Sbjct: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 172 bits (418), Expect = 4e-42
Identities = 97/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
P + + L++T+G+G + +V+LA + T + VA+KI+D + + + +E+ I KML
Sbjct: 4 PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA-VDCPENIKKEICINKML 62
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+H N+VK + YL +EY SGGE+FD + M E +A+ F Q+++ V Y H
Sbjct: 63 NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGK 211
I HRD+K ENLLLD N+KI+DFG + F + L+ CG+ PY APEL + +
Sbjct: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFD--GSTLRELRERVLRGKYRIPFYMSTDCE-NLL 268
++ VDVWS G++L +++G LP+D + +E + + Y P+ LL
Sbjct: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
Query: 269 KKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYV 304
K LV NP+ R ++ I +D+W N ++ RP V
Sbjct: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 172 bits (418), Expect = 4e-42
Identities = 97/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
P + + L++T+G+G + +V+LA + T + VA+KI+D + + + +E+ I KML
Sbjct: 4 PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA-VDCPENIKKEICINKML 62
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+H N+VK + YL +EY SGGE+FD + M E +A+ F Q+++ V Y H
Sbjct: 63 NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGK 211
I HRD+K ENLLLD N+KI+DFG + F + L+ CG+ PY APEL + +
Sbjct: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFD--GSTLRELRERVLRGKYRIPFYMSTDCE-NLL 268
++ VDVWS G++L +++G LP+D + +E + + Y P+ LL
Sbjct: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
Query: 269 KKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYV 304
K LV NP+ R ++ I +D+W N ++ RP V
Sbjct: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 172 bits (418), Expect = 4e-42
Identities = 97/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
P + + L++T+G+G + +V+LA + T + VA+KI+D + + + +E+ I KML
Sbjct: 4 PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA-VDCPENIKKEICINKML 62
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+H N+VK + YL +EY SGGE+FD + M E +A+ F Q+++ V Y H
Sbjct: 63 NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGK 211
I HRD+K ENLLLD N+KI+DFG + F + L+ CG+ PY APEL + +
Sbjct: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFD--GSTLRELRERVLRGKYRIPFYMSTDCE-NLL 268
++ VDVWS G++L +++G LP+D + +E + + Y P+ LL
Sbjct: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
Query: 269 KKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYV 304
K LV NP+ R ++ I +D+W N ++ RP V
Sbjct: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 172 bits (418), Expect = 4e-42
Identities = 97/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
P + + L++T+G+G + +V+LA + T + VA+KI+D + + + +E+ I KML
Sbjct: 4 PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA-VDCPENIKKEICINKML 62
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+H N+VK + YL +EY SGGE+FD + M E +A+ F Q+++ V Y H
Sbjct: 63 NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGK 211
I HRD+K ENLLLD N+KI+DFG + F + L+ CG+ PY APEL + +
Sbjct: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFD--GSTLRELRERVLRGKYRIPFYMSTDCE-NLL 268
++ VDVWS G++L +++G LP+D + +E + + Y P+ LL
Sbjct: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
Query: 269 KKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYV 304
K LV NP+ R ++ I +D+W N ++ RP V
Sbjct: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 172 bits (418), Expect = 4e-42
Identities = 97/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)
Query: 35 PHIGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKML 94
P + + L++T+G+G + +V+LA + T + VA+KI+D + + + +E+ I KML
Sbjct: 4 PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA-VDCPENIKKEICINKML 62
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+H N+VK + YL +EY SGGE+FD + M E +A+ F Q+++ V Y H
Sbjct: 63 NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAK---LDTFCGSPPYAAPELFQGK 211
I HRD+K ENLLLD N+KI+DFG + F + L+ CG+ PY APEL + +
Sbjct: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFD--GSTLRELRERVLRGKYRIPFYMSTDCE-NLL 268
++ VDVWS G++L +++G LP+D + +E + + Y P+ LL
Sbjct: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
Query: 269 KKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYV 304
K LV NP+ R ++ I +D+W N ++ RP V
Sbjct: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 171 bits (417), Expect = 5e-42
Identities = 97/261 (37%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI ++L H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 171 bits (416), Expect = 7e-42
Identities = 90/246 (36%), Positives = 139/246 (56%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQ-LNPGSLQKLFREVRIMKML- 94
I ++ ++ +GKG+F KV LA+ TG A+K++ K L ++ E RI+ +
Sbjct: 351 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLAR 410
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
+HP + +LF +T L+ VME+ +GG++ ++ R E AR +I+SA+ + H
Sbjct: 411 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 470
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
K II+RDLK +N+LLD E + K+ADFG E G TFCG+P Y APE+ Q Y
Sbjct: 471 DKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 530
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
GP VD W++GV+LY ++ G PF+ +L E +L + P ++ D +LK F+
Sbjct: 531 -GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMT 589
Query: 274 LNPAKR 279
NP R
Sbjct: 590 KNPTMR 595
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 171 bits (416), Expect = 7e-42
Identities = 95/262 (36%), Positives = 149/262 (56%), Gaps = 9/262 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ V G+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YL+ + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL ++ +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPY- 190
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 191 GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 250
Query: 271 FLVLNPAKRASLESIMRDKWMN 292
L +NP+KR + ++ W++
Sbjct: 251 MLTINPSKRITAAEALKHPWIS 272
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 171 bits (416), Expect = 7e-42
Identities = 95/262 (36%), Positives = 149/262 (56%), Gaps = 9/262 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ V G+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YL+ + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL ++ +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPY- 190
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 191 GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 250
Query: 271 FLVLNPAKRASLESIMRDKWMN 292
L +NP+KR + ++ W++
Sbjct: 251 MLTINPSKRITAAEALKHPWIS 272
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 171 bits (416), Expect = 7e-42
Identities = 95/262 (36%), Positives = 149/262 (56%), Gaps = 9/262 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ V G+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YL+ + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL ++ +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPY- 190
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 191 GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 250
Query: 271 FLVLNPAKRASLESIMRDKWMN 292
L +NP+KR + ++ W++
Sbjct: 251 MLTINPSKRITAAEALKHPWIS 272
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 171 bits (416), Expect = 7e-42
Identities = 95/262 (36%), Positives = 149/262 (56%), Gaps = 9/262 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ V G+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 61 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 120
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YL+ + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 121 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 180
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL ++ +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 181 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPY- 239
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 240 GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 299
Query: 271 FLVLNPAKRASLESIMRDKWMN 292
L +NP+KR + ++ W++
Sbjct: 300 MLTINPSKRITAAEALKHPWIS 321
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 171 bits (415), Expect = 9e-42
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y +G G F++V LA+ T K VAIK I K L G + E+ ++ + HPNI
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALE-GKEGSMENEIAVLHKIKHPNI 78
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYL+M+ SGGE+FD +V G E++A Q++ AV+Y H I+
Sbjct: 79 VALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIV 138
Query: 160 HRDLKAENLL---LDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL LD + I I+DFG S PG+ L T CG+P Y APE+ K Y
Sbjct: 139 HRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY-SK 197
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 198 AVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLM 257
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E ++ W+
Sbjct: 258 EKDPEKRFTCEQALQHPWI 276
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 171 bits (415), Expect = 9e-42
Identities = 84/256 (32%), Positives = 147/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L E+ ++ A+ YCH
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL + +KIADFG+S P + T CG+ Y PE+ +G+ ++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMHN- 251
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + T ++L+ K L N
Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311
Query: 276 PAKRASLESIMRDKWM 291
P++R L + W+
Sbjct: 312 PSERLPLAQVSAHPWV 327
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 171 bits (415), Expect = 9e-42
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y +G G F++V LA+ T K VAIK I K L G + E+ ++ + HPNI
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALE-GKEGSMENEIAVLHKIKHPNI 78
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYL+M+ SGGE+FD +V G E++A Q++ AV+Y H I+
Sbjct: 79 VALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIV 138
Query: 160 HRDLKAENLL---LDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL LD + I I+DFG S PG+ L T CG+P Y APE+ K Y
Sbjct: 139 HRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY-SK 197
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 198 AVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLM 257
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E ++ W+
Sbjct: 258 EKDPEKRFTCEQALQHPWI 276
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 171 bits (415), Expect = 9e-42
Identities = 98/259 (37%), Positives = 144/259 (55%), Gaps = 9/259 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y +G G F++V LA+ T K VAIK I K L G + E+ ++ + HPNI
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALE-GKEGSMENEIAVLHKIKHPNI 78
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V L + E+ LYL+M+ SGGE+FD +V G E++A Q++ AV+Y H I+
Sbjct: 79 VALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIV 138
Query: 160 HRDLKAENLL---LDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGP 216
HRDLK ENLL LD + I I+DFG S PG+ L T CG+P Y APE+ K Y
Sbjct: 139 HRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY-SK 197
Query: 217 EVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLKKFL 272
VD WS+GVI Y L+ G PF +L E++L+ +Y P++ +S ++ ++ +
Sbjct: 198 AVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLM 257
Query: 273 VLNPAKRASLESIMRDKWM 291
+P KR + E ++ W+
Sbjct: 258 EKDPEKRFTCEQALQHPWI 276
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 171 bits (415), Expect = 9e-42
Identities = 84/256 (32%), Positives = 147/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L E+ ++ A+ YCH
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL + +KIADFG+S P + T CG+ Y PE+ +G+ ++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMHN- 251
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + T ++L+ K L N
Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311
Query: 276 PAKRASLESIMRDKWM 291
P++R L + W+
Sbjct: 312 PSERLPLAQVSAHPWV 327
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 171 bits (415), Expect = 9e-42
Identities = 95/262 (36%), Positives = 149/262 (56%), Gaps = 9/262 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + +GKG F+ V+ V G+E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YL+ + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL ++ +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPY- 190
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF L +++ G Y P ++ + ++L+ K
Sbjct: 191 GKPVDLWACGVILYILLVGYPPFWDEDQHRLYKQIKAGAYDFPSPEWDTVTPEAKDLINK 250
Query: 271 FLVLNPAKRASLESIMRDKWMN 292
L +NP+KR + ++ W++
Sbjct: 251 MLTINPSKRITAAEALKHPWIS 272
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 171 bits (415), Expect = 9e-42
Identities = 84/256 (32%), Positives = 147/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L E+ ++ A+ YCH
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL + +KIADFG+S P + T CG+ Y PE+ +G+ ++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMHN- 251
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + T ++L+ K L N
Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311
Query: 276 PAKRASLESIMRDKWM 291
P++R L + W+
Sbjct: 312 PSERLPLAQVSAHPWV 327
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 171 bits (415), Expect = 9e-42
Identities = 84/256 (32%), Positives = 147/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L E+ ++ A+ YCH
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL + +KIADFG+S P + T CG+ Y PE+ +G+ ++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMHN- 251
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + T ++L+ K L N
Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311
Query: 276 PAKRASLESIMRDKWM 291
P++R L + W+
Sbjct: 312 PSERLPLAQVSAHPWV 327
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 171 bits (415), Expect = 9e-42
Identities = 84/256 (32%), Positives = 147/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L E+ ++ A+ YCH
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL + +KIADFG+S P + T CG+ Y PE+ +G+ ++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMHN- 251
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + T ++L+ K L N
Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311
Query: 276 PAKRASLESIMRDKWM 291
P++R L + W+
Sbjct: 312 PSERLPLAQVSAHPWV 327
>AF112472-1|AAD03744.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 170 bits (414), Expect = 1e-41
Identities = 96/261 (36%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI +++ H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLVKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILXAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>AF112471-1|AAD03743.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 517
Score = 170 bits (414), Expect = 1e-41
Identities = 96/261 (36%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+Y+L + IGKG F+ V+ + TG E A KII+ +L+ QKL RE RI +++ H N
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLVKHSN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A +QI+ AV +CHQ +
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILXAVLHCHQMGV 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + ++ W+
Sbjct: 252 MLTINPAKRITAHEALKHPWV 272
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 170 bits (413), Expect = 2e-41
Identities = 89/237 (37%), Positives = 138/237 (58%), Gaps = 4/237 (1%)
Query: 44 KTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPNIVKL 102
KT+G G+F +V L KH T + A+KI+DK ++ ++ E RI++ ++ P +V+L
Sbjct: 48 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRL 107
Query: 103 FQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRD 162
+ LY+VMEY GGE+F +L GR E AR QIV +Y H +I+RD
Sbjct: 108 EYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167
Query: 163 LKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWS 222
LK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+ VD W+
Sbjct: 168 LKPENLLIDHQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVDWWA 224
Query: 223 LGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKR 279
LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L ++ KR
Sbjct: 225 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 170 bits (413), Expect = 2e-41
Identities = 89/237 (37%), Positives = 138/237 (58%), Gaps = 4/237 (1%)
Query: 44 KTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPNIVKL 102
KT+G G+F +V L KH T + A+KI+DK ++ ++ E RI++ ++ P +V+L
Sbjct: 95 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRL 154
Query: 103 FQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRD 162
+ LY+VMEY GGE+F +L GR E AR QIV +Y H +I+RD
Sbjct: 155 EYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 214
Query: 163 LKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWS 222
LK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+ VD W+
Sbjct: 215 LKPENLLIDHQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVDWWA 271
Query: 223 LGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKR 279
LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L ++ KR
Sbjct: 272 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 328
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 170 bits (413), Expect = 2e-41
Identities = 89/237 (37%), Positives = 138/237 (58%), Gaps = 4/237 (1%)
Query: 44 KTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPNIVKL 102
KT+G G+F +V L KH T + A+KI+DK ++ ++ E RI++ ++ P +V+L
Sbjct: 95 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRL 154
Query: 103 FQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRD 162
+ LY+VMEY GGE+F +L GR E AR QIV +Y H +I+RD
Sbjct: 155 EYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 214
Query: 163 LKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWS 222
LK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+ VD W+
Sbjct: 215 LKPENLLIDHQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVDWWA 271
Query: 223 LGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKR 279
LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L ++ KR
Sbjct: 272 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 328
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 170 bits (413), Expect = 2e-41
Identities = 89/237 (37%), Positives = 138/237 (58%), Gaps = 4/237 (1%)
Query: 44 KTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPNIVKL 102
KT+G G+F +V L KH T + A+KI+DK ++ ++ E RI++ ++ P +V+L
Sbjct: 48 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRL 107
Query: 103 FQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRD 162
+ LY+VMEY GGE+F +L GR E AR QIV +Y H +I+RD
Sbjct: 108 EYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167
Query: 163 LKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWS 222
LK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+ VD W+
Sbjct: 168 LKPENLLIDHQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVDWWA 224
Query: 223 LGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKR 279
LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L ++ KR
Sbjct: 225 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 170 bits (413), Expect = 2e-41
Identities = 89/237 (37%), Positives = 138/237 (58%), Gaps = 4/237 (1%)
Query: 44 KTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPNIVKL 102
KT+G G+F +V L KH T + A+KI+DK ++ ++ E RI++ ++ P +V+L
Sbjct: 48 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRL 107
Query: 103 FQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRD 162
+ LY+VMEY GGE+F +L GR E AR QIV +Y H +I+RD
Sbjct: 108 EYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167
Query: 163 LKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWS 222
LK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+ VD W+
Sbjct: 168 LKPENLLIDHQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVDWWA 224
Query: 223 LGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKR 279
LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L ++ KR
Sbjct: 225 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 170 bits (413), Expect = 2e-41
Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+LD + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 170 bits (413), Expect = 2e-41
Identities = 89/237 (37%), Positives = 138/237 (58%), Gaps = 4/237 (1%)
Query: 44 KTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPNIVKL 102
KT+G G+F +V L KH T + A+KI+DK ++ ++ E RI++ ++ P +V+L
Sbjct: 74 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRL 133
Query: 103 FQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRD 162
+ LY+VMEY GGE+F +L GR E AR QIV +Y H +I+RD
Sbjct: 134 EYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 193
Query: 163 LKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWS 222
LK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+ VD W+
Sbjct: 194 LKPENLLIDHQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVDWWA 250
Query: 223 LGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKR 279
LGV++Y + +G PF ++ E+++ GK R P + S+D ++LL+ L ++ KR
Sbjct: 251 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 307
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 168 bits (409), Expect = 5e-41
Identities = 83/256 (32%), Positives = 146/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 101 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 160
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L E+ ++ A+ YCH
Sbjct: 161 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 220
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL + +KIADFG+S P + T CG+ Y PE+ +G+ ++
Sbjct: 221 KKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMHN- 278
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + ++L+ K L N
Sbjct: 279 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHN 338
Query: 276 PAKRASLESIMRDKWM 291
P++R L + W+
Sbjct: 339 PSERLPLAQVSAHPWV 354
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 168 bits (409), Expect = 5e-41
Identities = 83/256 (32%), Positives = 146/256 (57%), Gaps = 3/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L E+ ++ A+ YCH
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL + +KIADFG+S P + T CG+ Y PE+ +G+ ++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMHN- 251
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + ++L+ K L N
Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHN 311
Query: 276 PAKRASLESIMRDKWM 291
P++R L + W+
Sbjct: 312 PSERLPLAQVSAHPWV 327
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 167 bits (407), Expect = 8e-41
Identities = 91/242 (37%), Positives = 136/242 (56%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + TG+ A+KI+ K + + E R+++ HP
Sbjct: 152 FDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPF 211
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T L VMEYA+GGE+F +L E+ AR +IVSA++Y H + +
Sbjct: 212 LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDV 271
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RD+K ENL+LD + +IKI DFG E + GA + TFCG+P Y APE+ + Y G
Sbjct: 272 VYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY-GRA 330
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF L E +L + R P +S + ++LL L +P
Sbjct: 331 VDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPK 390
Query: 278 KR 279
+R
Sbjct: 391 QR 392
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 167 bits (407), Expect = 8e-41
Identities = 91/242 (37%), Positives = 136/242 (56%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + TG+ A+KI+ K + + E R+++ HP
Sbjct: 152 FDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPF 211
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T L VMEYA+GGE+F +L E+ AR +IVSA++Y H + +
Sbjct: 212 LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDV 271
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RD+K ENL+LD + +IKI DFG E + GA + TFCG+P Y APE+ + Y G
Sbjct: 272 VYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY-GRA 330
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF L E +L + R P +S + ++LL L +P
Sbjct: 331 VDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPK 390
Query: 278 KR 279
+R
Sbjct: 391 QR 392
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 167 bits (407), Expect = 8e-41
Identities = 92/242 (38%), Positives = 133/242 (54%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + +GK A+KI+ K + + E R++K HP
Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T+ L VMEY +GGE+F +L E R +IVSA+ Y H +I
Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RDLK ENL+ D + +IKI DFG E T A + TFCG+P Y APE+ + Y G
Sbjct: 268 VYRDLKLENLMRDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRA 326
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF +L E +L + P +S+D ++LL L+ +P
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 278 KR 279
KR
Sbjct: 387 KR 388
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 167 bits (407), Expect = 8e-41
Identities = 91/242 (37%), Positives = 136/242 (56%), Gaps = 3/242 (1%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 98
+ LK +GKG F KV L + TG+ A+KI+ K + + E R+++ HP
Sbjct: 152 FDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPF 211
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
+ L +T L VMEYA+GGE+F +L E+ AR +IVSA++Y H + +
Sbjct: 212 LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDV 271
Query: 159 IHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKYDGPE 217
++RD+K ENL+LD + +IKI DFG E + GA + TFCG+P Y APE+ + Y G
Sbjct: 272 VYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY-GRA 330
Query: 218 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPA 277
VD W LGV++Y ++ G LPF L E +L + R P +S + ++LL L +P
Sbjct: 331 VDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPK 390
Query: 278 KR 279
+R
Sbjct: 391 QR 392
>BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein.
Length = 390
Score = 167 bits (407), Expect = 8e-41
Identities = 103/292 (35%), Positives = 159/292 (54%), Gaps = 22/292 (7%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKT---QLNPGSLQKL----FREVRIM- 91
Y+ + +G+G + V+ H PT +E A+K+ID T +P +++L +EV I+
Sbjct: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILR 79
Query: 92 KMLDHPNIVKLFQVIETEKTLYLVMEY---ASGGEVFDYLVLHGRMKEKEARAKFRQIVS 148
K+ HPNI++L ET +LV + GE+FDYL + EKE R R ++
Sbjct: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLFHRMKRGELFDYLTEKATLSEKETRKIMRALLE 139
Query: 149 AVQYCHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF 208
+ H+ I+HRDLK EN+LLD MNIK+ DFGFS + PG +L CG+P Y APE+
Sbjct: 140 VICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEII 199
Query: 209 QGKKYD-----GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY-- 259
+ + G EVD+WS GVI+YTL++GS PF + ++ G Y+ P +
Sbjct: 200 ECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDD 259
Query: 260 MSTDCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPYVEPQQDFK 311
S ++L+ +FLV+ P R + E + + Y +E+R + P+ FK
Sbjct: 260 YSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQ-YLVEEVR-HFSPRGKFK 309
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 262 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 321
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 322 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 380
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 381 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 440
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 441 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 500
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 501 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 538
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 495
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 495
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 128 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 187
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 188 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 246
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 247 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 306
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 307 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 366
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 367 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 404
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 262 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 321
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 322 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 380
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 381 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 440
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 441 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 500
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 501 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 538
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 495
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 495
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 495
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 495
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 495
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 167 bits (406), Expect = 1e-40
Identities = 109/281 (38%), Positives = 157/281 (55%), Gaps = 20/281 (7%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMK 92
+Y + KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L+HP I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 153 CHQKRIIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF- 208
H+ IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 209 -QGKKYDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMST 262
G VD WSLGVIL+ +SG PF + T L++++ GKY IP +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 263 DCENLLKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+L+KK LV++P R + E +R W+ +ED R +
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 495
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 167 bits (406), Expect = 1e-40
Identities = 85/256 (33%), Positives = 146/256 (57%), Gaps = 4/256 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HPNI++L+ + +YL++EYA GE++ L E+ ++ A+ YCH
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDG 215
K++IHRD+K ENLLL + +KIADFG+S T + T CG+ Y PE+ +G + D
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAT-SLRRKTMCGTLDYLPPEMIEG-RIDN 251
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLN 275
+VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + T ++L+ K L N
Sbjct: 252 EKVDLWCIGVLCYELLVGN-PFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 310
Query: 276 PAKRASLESIMRDKWM 291
P++R L + W+
Sbjct: 311 PSERLPLAQVSAHPWV 326
>X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon
protein.
Length = 737
Score = 166 bits (404), Expect = 2e-40
Identities = 85/246 (34%), Positives = 139/246 (56%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQ-LNPGSLQKLFREVRIMKML- 94
+ ++ +K +GKG+F KV LA+ + A+K++ K L + E RI+ +
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
HP + +L+ +T+ L+ VMEY +GG++ + + E +R ++ SA+ + H
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
Q +I+RDLK +N+LLD E + K+ADFG E G TFCG+P Y APE+ Q +Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
GP VD W+LGV++Y +++G PF+ +L E +L P ++S + ++LK F+
Sbjct: 585 -GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMT 643
Query: 274 LNPAKR 279
NP KR
Sbjct: 644 KNPHKR 649
>BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 166 bits (404), Expect = 2e-40
Identities = 85/246 (34%), Positives = 139/246 (56%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQ-LNPGSLQKLFREVRIMKML- 94
+ ++ +K +GKG+F KV LA+ + A+K++ K L + E RI+ +
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
HP + +L+ +T+ L+ VMEY +GG++ + + E +R ++ SA+ + H
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
Q +I+RDLK +N+LLD E + K+ADFG E G TFCG+P Y APE+ Q +Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
GP VD W+LGV++Y +++G PF+ +L E +L P ++S + ++LK F+
Sbjct: 585 -GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMT 643
Query: 274 LNPAKR 279
NP KR
Sbjct: 644 KNPHKR 649
>BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 166 bits (404), Expect = 2e-40
Identities = 85/246 (34%), Positives = 139/246 (56%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQ-LNPGSLQKLFREVRIMKML- 94
+ ++ +K +GKG+F KV LA+ + A+K++ K L + E RI+ +
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 95 DHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH 154
HP + +L+ +T+ L+ VMEY +GG++ + + E +R ++ SA+ + H
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
Q +I+RDLK +N+LLD E + K+ADFG E G TFCG+P Y APE+ Q +Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
GP VD W+LGV++Y +++G PF+ +L E +L P ++S + ++LK F+
Sbjct: 585 -GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMT 643
Query: 274 LNPAKR 279
NP KR
Sbjct: 644 KNPHKR 649
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 166 bits (404), Expect = 2e-40
Identities = 94/262 (35%), Positives = 146/262 (55%), Gaps = 12/262 (4%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
KY + IG+G+F++V +H T + AIK+I+ T+ G + E+R+++ + H N
Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIE-TKYREGR-EVCESELRVLRRVRHAN 154
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L +V ET++ +Y+VME A+GGE+FD ++ G E++A + ++ V+Y H I
Sbjct: 155 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 214
Query: 159 IHRDLKAENLLL---DGEMNIKIADFGFSNEFTPG--AKLDTFCGSPPYAAPELFQGKKY 213
HRDLK ENLL + I I DFG ++ G + T CG+P Y APE+ K Y
Sbjct: 215 THRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPY 274
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKF-- 271
VD+W+LGVI Y L+SG++PF+ L ++LRGKY NL K F
Sbjct: 275 TN-SVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFID 333
Query: 272 --LVLNPAKRASLESIMRDKWM 291
L ++P R + +R W+
Sbjct: 334 RLLTVDPGARMTALQALRHPWV 355
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 166 bits (404), Expect = 2e-40
Identities = 89/237 (37%), Positives = 137/237 (57%), Gaps = 4/237 (1%)
Query: 44 KTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPNIVKL 102
KT+G G+F +V L KH T + A+KI+DK ++ ++ E RI++ ++ P +V+L
Sbjct: 48 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRL 107
Query: 103 FQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRD 162
+ LY+VMEY GGE+F +L GR E AR QIV +Y + II+RD
Sbjct: 108 EYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLNSLDIIYRD 167
Query: 163 LKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYDGPEVDVWS 222
LK ENLL+D + I++ DFGF+ + T CG+P Y APE+ K Y+ VD W+
Sbjct: 168 LKPENLLIDHQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVDWWA 224
Query: 223 LGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPAKR 279
LGV++Y + +G PF ++ E+++ GK R P S+D ++LL+ L ++ KR
Sbjct: 225 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSNFSSDLKDLLRNLLQVDLTKR 281
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 166 bits (404), Expect = 2e-40
Identities = 94/262 (35%), Positives = 146/262 (55%), Gaps = 12/262 (4%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
KY + IG+G+F++V +H T + AIK+I+ T+ G + E+R+++ + H N
Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIE-TKYREGR-EVCESELRVLRRVRHAN 154
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I++L +V ET++ +Y+VME A+GGE+FD ++ G E++A + ++ V+Y H I
Sbjct: 155 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 214
Query: 159 IHRDLKAENLLL---DGEMNIKIADFGFSNEFTPG--AKLDTFCGSPPYAAPELFQGKKY 213
HRDLK ENLL + I I DFG ++ G + T CG+P Y APE+ K Y
Sbjct: 215 THRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPY 274
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKF-- 271
VD+W+LGVI Y L+SG++PF+ L ++LRGKY NL K F
Sbjct: 275 TN-SVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFID 333
Query: 272 --LVLNPAKRASLESIMRDKWM 291
L ++P R + +R W+
Sbjct: 334 RLLTVDPGARMTALQALRHPWV 355
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 166 bits (404), Expect = 2e-40
Identities = 85/259 (32%), Positives = 148/259 (57%), Gaps = 6/259 (2%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQ-KLFREVRIMKMLD 95
I +++ + +GKG F V LA+ + VA+K++ K+Q+ ++ +L RE+ I L
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEA---RAKFRQIVSAVQY 152
HPNI++L+ + +YL++EYA G ++ L E+ RA ++ A+ Y
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGMLYKELQKSCTFDEQRTATVRAVMEELADALMY 193
Query: 153 CHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKK 212
CH K++IHRD+K ENLLL + +KIADFG+S P + T CG+ Y PE+ +G+
Sbjct: 194 CHGKKVIHRDIKPENLLLGLKGELKIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRM 252
Query: 213 YDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFL 272
++ +VD+W +GV+ Y L+ G+ PF+ ++ E R+++ + P + T ++L+ K L
Sbjct: 253 HN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLL 311
Query: 273 VLNPAKRASLESIMRDKWM 291
NP++R L + W+
Sbjct: 312 RHNPSERLPLAQVSAHPWV 330
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 166 bits (403), Expect = 2e-40
Identities = 93/246 (37%), Positives = 137/246 (55%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLD 95
+ +++ LK +GKG F KV L K TG+ A+KI+ K + + E R+++
Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH- 154
HP + L +T L VMEYA+GGE+F +L E AR +IVSA+ Y H
Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
+K +++RDLK ENL+LD + +IKI DFG E GA + TFCG+P Y APE+ + Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
G VD W LGV++Y ++ G LPF +L E +L + R P + + ++LL L
Sbjct: 327 -GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLK 385
Query: 274 LNPAKR 279
+P +R
Sbjct: 386 KDPKQR 391
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 166 bits (403), Expect = 2e-40
Identities = 93/246 (37%), Positives = 137/246 (55%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLD 95
+ +++ LK +GKG F KV L K TG+ A+KI+ K + + E R+++
Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH- 154
HP + L +T L VMEYA+GGE+F +L E AR +IVSA+ Y H
Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
+K +++RDLK ENL+LD + +IKI DFG E GA + TFCG+P Y APE+ + Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
G VD W LGV++Y ++ G LPF +L E +L + R P + + ++LL L
Sbjct: 327 -GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLK 385
Query: 274 LNPAKR 279
+P +R
Sbjct: 386 KDPKQR 391
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 166 bits (403), Expect = 2e-40
Identities = 93/246 (37%), Positives = 137/246 (55%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLD 95
+ +++ LK +GKG F KV L K TG+ A+KI+ K + + E R+++
Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH- 154
HP + L +T L VMEYA+GGE+F +L E AR +IVSA+ Y H
Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
+K +++RDLK ENL+LD + +IKI DFG E GA + TFCG+P Y APE+ + Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
G VD W LGV++Y ++ G LPF +L E +L + R P + + ++LL L
Sbjct: 327 -GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLK 385
Query: 274 LNPAKR 279
+P +R
Sbjct: 386 KDPKQR 391
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 166 bits (403), Expect = 2e-40
Identities = 93/246 (37%), Positives = 137/246 (55%), Gaps = 4/246 (1%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLD 95
+ +++ LK +GKG F KV L K TG+ A+KI+ K + + E R+++
Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCH- 154
HP + L +T L VMEYA+GGE+F +L E AR +IVSA+ Y H
Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 155 QKRIIHRDLKAENLLLDGEMNIKIADFGFSNE-FTPGAKLDTFCGSPPYAAPELFQGKKY 213
+K +++RDLK ENL+LD + +IKI DFG E GA + TFCG+P Y APE+ + Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 214 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKFLV 273
G VD W LGV++Y ++ G LPF +L E +L + R P + + ++LL L
Sbjct: 327 -GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLK 385
Query: 274 LNPAKR 279
+P +R
Sbjct: 386 KDPKQR 391
>BC034044-1|AAH34044.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 165 bits (402), Expect = 3e-40
Identities = 97/261 (37%), Positives = 147/261 (56%), Gaps = 11/261 (4%)
Query: 40 YKLLKTIGKGNFAKVK-LAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
Y+L + +GKG F+ V+ K PT +E A KII+ +L+ QKL RE RI ++L HPN
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTPT-QEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV+L I E YLV + +GGE+F+ +V E +A QI+ +V + HQ I
Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDI 132
Query: 159 IHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYD 214
+HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y
Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY- 191
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKK 270
G VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 271 FLVLNPAKRASLESIMRDKWM 291
L +NPAKR + + ++ W+
Sbjct: 252 MLTINPAKRITADQALKHPWV 272
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 447
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 564
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 656
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 447
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 564
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 656
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 447
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 564
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 656
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 447
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 564
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 656
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 82 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 140
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 141 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 200
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 201 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 257
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 258 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 317
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 318 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 349
>AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 447
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 564
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 656
>AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 447
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 564
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 656
>AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 447
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 564
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 656
>AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 447
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 564
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 656
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 165 bits (401), Expect = 4e-40
Identities = 91/259 (35%), Positives = 145/259 (55%), Gaps = 9/259 (3%)
Query: 37 IGKYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLN-PGSLQKLFREVRIMKMLD 95
+ +Y++ K IGKG FA V + TGK+ A K+++K L P L+K E+RI + LD
Sbjct: 36 VDRYRVGKQIGKGGFAIVYELTSIRTGKKYAGKVVEKAGLTKPKYLEKFMSEIRIHQSLD 95
Query: 96 HPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQ 155
HP+I K+++ E + YL++E S + L + + E E + QI+ AV Y H+
Sbjct: 96 HPHICKMYKHFEDNRYHYLILELCSNETLAHLLRVRECLTEPEVQYFLLQIIDAVSYLHK 155
Query: 156 KRIIHRDLKAENLLLDGEMNIKIADFGFSNEFT-PGAKLDTFCGSPPYAAPELFQG--KK 212
+ IIHRDLK N+ LD + +K+ D G + + P + T CG+P Y APE+ Q K+
Sbjct: 156 RCIIHRDLKLGNIFLDENLEVKVGDLGLAAQLNEPNERKKTMCGTPNYIAPEILQSNDKR 215
Query: 213 YDGPEVDVWSLGVILYTLVSGSLPFDGS----TLRELRERVLRGKYRIPFYMSTDCENLL 268
EVD+W++GVI YT++ G PFDG T R++RE L + ++S +
Sbjct: 216 AYSYEVDIWAVGVITYTMLIGKAPFDGGSKEITYRKIRENELSFPIK-DHHISHQARMFI 274
Query: 269 KKFLVLNPAKRASLESIMR 287
+ L +P +R +LE +++
Sbjct: 275 RSILNPDPTQRLTLEQMVQ 293
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 165 bits (401), Expect = 4e-40
Identities = 108/276 (39%), Positives = 154/276 (55%), Gaps = 20/276 (7%)
Query: 44 KTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQK------LFREVRIMKMLDHP 97
KT+G G +VKLA T K+VAIKII K + GS ++ + E+ I+K L+HP
Sbjct: 3 KTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHP 62
Query: 98 NIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKR 157
I+K+ + E Y+V+E GGE+FD +V + R+KE + F Q++ AVQY H+
Sbjct: 63 CIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENG 121
Query: 158 IIHRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKLDTFCGSPPYAAPELF--QGKK 212
IIHRDLK EN+LL + IKI DFG S + + T CG+P Y APE+ G
Sbjct: 122 IIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTA 181
Query: 213 YDGPEVDVWSLGVILYTLVSGSLPF-DGSTLRELRERVLRGKYR-IP---FYMSTDCENL 267
VD WSLGVIL+ +SG PF + T L++++ GKY IP +S +L
Sbjct: 182 GYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDL 241
Query: 268 LKKFLVLNPAKRASLESIMRDKWMNTGYEEDELRPY 303
+KK LV++P R + E +R W+ +ED R +
Sbjct: 242 VKKLLVVDPKARFTTEEALRHPWLQ---DEDMKRKF 274
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 165 bits (401), Expect = 4e-40
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 15/272 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
+YK+ +TIG GNFA VK T +E A+KII K++ G + EV I++ + HPN
Sbjct: 454 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR-GKEHMIQNEVSILRRVKHPN 512
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
IV L + ++ LYLVME GG++FD + + E++A + SA++Y H I
Sbjct: 513 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 572
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 573 VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDGPLYTVCGTPTYVAPEIIAETGY- 629
Query: 215 GPEVDVWSLGVILYTLVSGSLPFDGS--TLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF GS L +++L G+ + P++ +S + L+
Sbjct: 630 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 689
Query: 269 KKFLVLNPAKRASLESIMRDKWMN-TGYEEDE 299
L+++ +R S ++ W+N G E+E
Sbjct: 690 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENE 721
>U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-dependent
protein kinase II protein.
Length = 315
Score = 165 bits (400), Expect = 6e-40
Identities = 94/260 (36%), Positives = 145/260 (55%), Gaps = 9/260 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L + +GKG F+ V+ + +E A KII+ +L+ QKL RE RI ++L HPNI
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V+L I E YLV + +GGE+F+ +V E +A QI+ +V + HQ I+
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 160 HRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYDG 215
HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y G
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-G 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKF 271
VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 272 LVLNPAKRASLESIMRDKWM 291
L +NPAKR + + ++ W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 165 bits (400), Expect = 6e-40
Identities = 89/269 (33%), Positives = 140/269 (52%), Gaps = 4/269 (1%)
Query: 35 PHIGK-YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMK 92
P G+ Y + +GKG FA+ A TG A+K+I ++++ P +K+ E+ + +
Sbjct: 17 PRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHR 76
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L H +IV+ E +Y+ +E S + + E E R RQI+S ++Y
Sbjct: 77 DLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKY 136
Query: 153 CHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEF-TPGAKLDTFCGSPPYAAPELFQGK 211
HQ+ I+HRDLK N + M +K+ DFG + P + T CG+P Y APE+ +
Sbjct: 137 LHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLL-R 195
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKF 271
+ GPE DVWSLG ++YTL+ GS PF+ + L+E + + Y +P +S LL
Sbjct: 196 QGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAI 255
Query: 272 LVLNPAKRASLESIMRDKWMNTGYEEDEL 300
L +P R S++ I+R + GY D L
Sbjct: 256 LRASPRDRPSIDQILRHDFFTKGYTPDRL 284
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 165 bits (400), Expect = 6e-40
Identities = 89/269 (33%), Positives = 140/269 (52%), Gaps = 4/269 (1%)
Query: 35 PHIGK-YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMK 92
P G+ Y + +GKG FA+ A TG A+K+I ++++ P +K+ E+ + +
Sbjct: 56 PRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHR 115
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L H +IV+ E +Y+ +E S + + E E R RQI+S ++Y
Sbjct: 116 DLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKY 175
Query: 153 CHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEF-TPGAKLDTFCGSPPYAAPELFQGK 211
HQ+ I+HRDLK N + M +K+ DFG + P + T CG+P Y APE+ +
Sbjct: 176 LHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLL-R 234
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKF 271
+ GPE DVWSLG ++YTL+ GS PF+ + L+E + + Y +P +S LL
Sbjct: 235 QGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAI 294
Query: 272 LVLNPAKRASLESIMRDKWMNTGYEEDEL 300
L +P R S++ I+R + GY D L
Sbjct: 295 LRASPRDRPSIDQILRHDFFTKGYTPDRL 323
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 165 bits (400), Expect = 6e-40
Identities = 89/269 (33%), Positives = 140/269 (52%), Gaps = 4/269 (1%)
Query: 35 PHIGK-YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMK 92
P G+ Y + +GKG FA+ A TG A+K+I ++++ P +K+ E+ + +
Sbjct: 56 PRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHR 115
Query: 93 MLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQY 152
L H +IV+ E +Y+ +E S + + E E R RQI+S ++Y
Sbjct: 116 DLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKY 175
Query: 153 CHQKRIIHRDLKAENLLLDGEMNIKIADFGFSNEF-TPGAKLDTFCGSPPYAAPELFQGK 211
HQ+ I+HRDLK N + M +K+ DFG + P + T CG+P Y APE+ +
Sbjct: 176 LHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLL-R 234
Query: 212 KYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLKKF 271
+ GPE DVWSLG ++YTL+ GS PF+ + L+E + + Y +P +S LL
Sbjct: 235 QGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAI 294
Query: 272 LVLNPAKRASLESIMRDKWMNTGYEEDEL 300
L +P R S++ I+R + GY D L
Sbjct: 295 LRASPRDRPSIDQILRHDFFTKGYTPDRL 323
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 165 bits (400), Expect = 6e-40
Identities = 95/264 (35%), Positives = 148/264 (56%), Gaps = 14/264 (5%)
Query: 39 KYKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPN 98
KYK+ K IG GNFA VK TGKE A+KIIDK + G + EV I++ + HPN
Sbjct: 343 KYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCC-GKEHLIENEVSILRRVKHPN 401
Query: 99 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRI 158
I+ L + +ET L+LVME GG++FD + + E++ A + +A++Y H I
Sbjct: 402 IIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSI 461
Query: 159 IHRDLKAENLLL----DGEMNIKIADFGFSNEFTPGAKLDTFCGSPPYAAPELFQGKKYD 214
+HRD+K ENLL+ DG ++K+ DFG + L T CG+P Y APE+ Y
Sbjct: 462 VHRDIKPENLLVCEYPDGTKSLKLGDFGLAT--VVEGPLYTVCGTPTYVAPEIIAETGY- 518
Query: 215 GPEVDVWSLGVILYTLVSGSLPF--DGSTLRELRERVLRGK--YRIPFY--MSTDCENLL 268
G +VD+W+ GVI Y L+ G PF + + +L +++L GK + P++ ++ + L+
Sbjct: 519 GLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELI 578
Query: 269 KKFLVLNPAKRASLESIMRDKWMN 292
+ L +N R + I+ W++
Sbjct: 579 SQMLQVNVEARCTAGQILSHPWVS 602
>AL713896-5|CAI13788.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 165 bits (400), Expect = 6e-40
Identities = 94/260 (36%), Positives = 145/260 (55%), Gaps = 9/260 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L + +GKG F+ V+ + +E A KII+ +L+ QKL RE RI ++L HPNI
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V+L I E YLV + +GGE+F+ +V E +A QI+ +V + HQ I+
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 160 HRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYDG 215
HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y G
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-G 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKF 271
VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 272 LVLNPAKRASLESIMRDKWM 291
L +NPAKR + + ++ W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>AL713896-4|CAI13789.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 165 bits (400), Expect = 6e-40
Identities = 94/260 (36%), Positives = 145/260 (55%), Gaps = 9/260 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L + +GKG F+ V+ + +E A KII+ +L+ QKL RE RI ++L HPNI
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V+L I E YLV + +GGE+F+ +V E +A QI+ +V + HQ I+
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 160 HRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYDG 215
HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y G
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-G 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKF 271
VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 272 LVLNPAKRASLESIMRDKWM 291
L +NPAKR + + ++ W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>AL713896-3|CAI13790.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 165 bits (400), Expect = 6e-40
Identities = 94/260 (36%), Positives = 145/260 (55%), Gaps = 9/260 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L + +GKG F+ V+ + +E A KII+ +L+ QKL RE RI ++L HPNI
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V+L I E YLV + +GGE+F+ +V E +A QI+ +V + HQ I+
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 160 HRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYDG 215
HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y G
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-G 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKF 271
VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 272 LVLNPAKRASLESIMRDKWM 291
L +NPAKR + + ++ W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>AL713896-2|CAI13791.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 165 bits (400), Expect = 6e-40
Identities = 94/260 (36%), Positives = 145/260 (55%), Gaps = 9/260 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L + +GKG F+ V+ + +E A KII+ +L+ QKL RE RI ++L HPNI
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V+L I E YLV + +GGE+F+ +V E +A QI+ +V + HQ I+
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 160 HRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYDG 215
HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y G
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-G 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKF 271
VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 272 LVLNPAKRASLESIMRDKWM 291
L +NPAKR + + ++ W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>AL596247-5|CAI13967.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 165 bits (400), Expect = 6e-40
Identities = 94/260 (36%), Positives = 145/260 (55%), Gaps = 9/260 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L + +GKG F+ V+ + +E A KII+ +L+ QKL RE RI ++L HPNI
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V+L I E YLV + +GGE+F+ +V E +A QI+ +V + HQ I+
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 160 HRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYDG 215
HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y G
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-G 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKF 271
VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 272 LVLNPAKRASLESIMRDKWM 291
L +NPAKR + + ++ W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>AL596247-4|CAI13966.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 165 bits (400), Expect = 6e-40
Identities = 94/260 (36%), Positives = 145/260 (55%), Gaps = 9/260 (3%)
Query: 40 YKLLKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 99
Y+L + +GKG F+ V+ + +E A KII+ +L+ QKL RE RI ++L HPNI
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 100 VKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRII 159
V+L I E YLV + +GGE+F+ +V E +A QI+ +V + HQ I+
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 160 HRDLKAENLLLDGEMN---IKIADFGFSNEFTPGAKL-DTFCGSPPYAAPELFQGKKYDG 215
HRDLK ENLLL + +K+ADFG + E + F G+P Y +PE+ + Y G
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY-G 192
Query: 216 PEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLKKF 271
VD+W+ GVILY L+ G PF +L +++ G Y P ++ + +NL+ +
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 272 LVLNPAKRASLESIMRDKWM 291
L +NPAKR + + ++ W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 71,768,241
Number of Sequences: 224733
Number of extensions: 2649343
Number of successful extensions: 15308
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2547
Number of HSP's successfully gapped in prelim test: 280
Number of HSP's that attempted gapping in prelim test: 6416
Number of HSP's gapped (non-prelim): 3601
length of query: 652
length of database: 73,234,838
effective HSP length: 95
effective length of query: 557
effective length of database: 51,885,203
effective search space: 28900058071
effective search space used: 28900058071
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)
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