Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000130-TA|BGIBMGA000130-PA|IPR001611|Leucine-rich
repeat, IPR003591|Leucine-rich repeat, typical subtype
(370 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 105 3e-22
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 105 3e-22
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 105 3e-22
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 105 3e-22
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 105 3e-22
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 105 3e-22
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 103 1e-21
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 98 4e-20
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 98 4e-20
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 98 4e-20
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 98 4e-20
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 98 4e-20
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 98 4e-20
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 98 4e-20
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 98 4e-20
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 98 4e-20
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 98 4e-20
BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat con... 94 6e-19
AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat con... 94 6e-19
AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens ... 94 6e-19
AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich repeat-con... 94 8e-19
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 87 9e-17
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 87 9e-17
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 87 9e-17
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 87 9e-17
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 87 9e-17
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 85 5e-16
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 85 5e-16
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 85 5e-16
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 84 9e-16
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 84 9e-16
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 84 9e-16
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 84 9e-16
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 84 9e-16
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 81 6e-15
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 81 6e-15
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 81 6e-15
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 81 6e-15
BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein. 78 6e-14
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 78 6e-14
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 78 6e-14
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 78 6e-14
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 78 6e-14
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 78 6e-14
BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat con... 77 8e-14
AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein. 77 8e-14
BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats an... 76 2e-13
AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein. 76 2e-13
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 75 5e-13
BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat con... 75 5e-13
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 75 5e-13
AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein. 75 5e-13
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 75 5e-13
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 75 5e-13
AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat con... 75 5e-13
AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat con... 75 5e-13
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 75 5e-13
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 75 5e-13
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 75 5e-13
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 74 9e-13
BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats an... 73 1e-12
BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein. 73 1e-12
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 73 1e-12
AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal p... 73 1e-12
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 73 2e-12
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 73 2e-12
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 73 2e-12
AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat con... 73 2e-12
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 73 2e-12
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 72 3e-12
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 72 3e-12
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 72 3e-12
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 72 3e-12
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 72 3e-12
L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein. 71 7e-12
CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein. 71 7e-12
CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein. 71 7e-12
BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein ... 71 7e-12
BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein. 71 7e-12
BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein ... 71 7e-12
AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein ... 71 7e-12
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 70 1e-11
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 70 1e-11
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 70 1e-11
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 70 1e-11
BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein. 70 2e-11
BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein. 70 2e-11
BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat con... 70 2e-11
AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens ... 70 2e-11
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 69 3e-11
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 68 5e-11
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 68 5e-11
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 68 5e-11
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 68 5e-11
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 66 1e-10
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 66 2e-10
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 66 2e-10
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 66 2e-10
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 66 2e-10
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 64 6e-10
BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat con... 64 1e-09
AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein. 64 1e-09
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 63 1e-09
BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein. 63 2e-09
BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and... 63 2e-09
AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein pr... 63 2e-09
AL445222-17|CAH72930.1| 723|Homo sapiens leucine rich repeat an... 63 2e-09
AL445222-16|CAH72931.1| 696|Homo sapiens leucine rich repeat an... 63 2e-09
AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein ... 63 2e-09
AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and... 62 3e-09
BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein. 61 7e-09
AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich... 61 7e-09
AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich... 61 7e-09
BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats an... 60 1e-08
AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens ... 60 2e-08
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 59 3e-08
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 59 3e-08
AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats an... 58 4e-08
AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats an... 58 4e-08
AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats an... 58 4e-08
AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar t... 56 2e-07
BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat con... 55 3e-07
BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat con... 55 3e-07
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 54 6e-07
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 54 6e-07
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 54 8e-07
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 54 8e-07
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 54 8e-07
AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein. 54 8e-07
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 54 8e-07
AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat con... 54 1e-06
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 52 3e-06
AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat con... 52 4e-06
AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat con... 52 4e-06
AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats an... 52 4e-06
AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat con... 52 4e-06
AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats an... 52 4e-06
AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat con... 52 4e-06
AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein... 52 4e-06
BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein. 51 6e-06
BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein. 51 6e-06
AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isofor... 51 6e-06
AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isofor... 51 6e-06
AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein. 51 6e-06
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 51 8e-06
BC026112-1|AAH26112.1| 116|Homo sapiens hypothetical protein LO... 51 8e-06
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 51 8e-06
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 51 8e-06
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 51 8e-06
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 50 1e-05
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 50 1e-05
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 50 1e-05
AK127177-1|BAC86870.1| 279|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 50 1e-05
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 49 3e-05
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 48 4e-05
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 48 4e-05
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 48 4e-05
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 48 4e-05
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 48 4e-05
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 48 7e-05
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 48 7e-05
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 48 7e-05
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 48 7e-05
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 48 7e-05
AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens ... 47 1e-04
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 46 2e-04
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 46 2e-04
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 46 2e-04
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 46 2e-04
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 46 2e-04
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 46 2e-04
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 46 2e-04
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 46 2e-04
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 45 4e-04
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 45 4e-04
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 45 4e-04
BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat con... 45 4e-04
AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat con... 45 4e-04
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 45 4e-04
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 45 4e-04
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 45 4e-04
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 45 4e-04
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 45 4e-04
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 45 5e-04
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 44 7e-04
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 44 7e-04
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 44 7e-04
AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1) p... 44 7e-04
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 44 7e-04
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 44 9e-04
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 9e-04
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 9e-04
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 44 9e-04
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 44 9e-04
BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein. 44 9e-04
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 44 9e-04
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 44 9e-04
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 44 9e-04
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 44 9e-04
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 9e-04
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 44 9e-04
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 44 9e-04
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 44 9e-04
AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein. 44 9e-04
AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein. 44 9e-04
AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate proteog... 44 9e-04
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 44 9e-04
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 44 0.001
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 44 0.001
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 44 0.001
BC024001-1|AAH24001.1| 184|Homo sapiens leucine rich repeat con... 44 0.001
AY358318-1|AAQ88684.1| 184|Homo sapiens LKKM2429 protein. 44 0.001
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 44 0.001
AL355138-5|CAI12601.1| 134|Homo sapiens leucine rich repeat con... 44 0.001
AL355138-4|CAI12602.1| 175|Homo sapiens leucine rich repeat con... 44 0.001
AL355138-2|CAI12600.1| 184|Homo sapiens leucine rich repeat con... 44 0.001
AK094734-1|BAC04409.1| 184|Homo sapiens protein ( Homo sapiens ... 44 0.001
AK001706-1|BAA91849.1| 184|Homo sapiens protein ( Homo sapiens ... 44 0.001
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 44 0.001
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 43 0.002
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 43 0.002
BC050097-1|AAH50097.1| 383|Homo sapiens LRRC27 protein protein. 43 0.002
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 43 0.002
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 43 0.002
AL590105-6|CAI13017.1| 530|Homo sapiens novel protein protein. 43 0.002
AL590105-5|CAI13016.1| 383|Homo sapiens novel protein protein. 43 0.002
AK098652-1|BAC05366.1| 383|Homo sapiens protein ( Homo sapiens ... 43 0.002
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 43 0.002
AB051461-1|BAB21765.1| 538|Homo sapiens KIAA1674 protein protein. 43 0.002
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 43 0.002
BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomeras... 43 0.002
AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signalin... 43 0.002
AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein. 42 0.003
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 42 0.003
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 42 0.003
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 42 0.005
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 42 0.005
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 42 0.005
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 42 0.005
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 42 0.005
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 42 0.005
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 41 0.006
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 41 0.006
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 41 0.006
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 41 0.006
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 41 0.006
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 41 0.006
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 41 0.006
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 41 0.006
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 41 0.006
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 41 0.008
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 41 0.008
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 41 0.008
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 41 0.008
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 41 0.008
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 41 0.008
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 41 0.008
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 41 0.008
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 41 0.008
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 41 0.008
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 41 0.008
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 41 0.008
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 40 0.011
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 40 0.011
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 40 0.011
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 40 0.011
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 40 0.011
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 40 0.011
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 40 0.011
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 40 0.011
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 40 0.011
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 40 0.011
AL590105-8|CAI13019.1| 468|Homo sapiens novel protein protein. 40 0.011
AL590105-7|CAI13018.1| 257|Homo sapiens novel protein protein. 40 0.011
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 40 0.011
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 40 0.011
AK093250-1|BAC04108.1| 468|Homo sapiens protein ( Homo sapiens ... 40 0.011
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 40 0.011
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 40 0.011
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 40 0.011
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 40 0.011
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 40 0.011
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 40 0.011
AK092954-1|BAC04007.1| 325|Homo sapiens protein ( Homo sapiens ... 40 0.014
BC056900-1|AAH56900.1| 1504|Homo sapiens nischarin protein. 40 0.019
BC054494-1|AAH54494.1| 1504|Homo sapiens nischarin protein. 40 0.019
BC038102-1|AAH38102.1| 1504|Homo sapiens nischarin protein. 40 0.019
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 40 0.019
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 40 0.019
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 40 0.019
AF082516-1|AAC33104.1| 1504|Homo sapiens I-1 receptor candidate ... 40 0.019
AB023192-1|BAA76819.1| 1528|Homo sapiens KIAA0975 protein protein. 40 0.019
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 39 0.025
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 39 0.025
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 39 0.025
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 39 0.025
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 39 0.025
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 39 0.025
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 39 0.032
DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kin... 38 0.043
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 38 0.043
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 38 0.043
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 38 0.043
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 38 0.043
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 38 0.043
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 38 0.043
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 38 0.057
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 38 0.057
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 38 0.057
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 38 0.057
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 38 0.057
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 38 0.057
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 38 0.057
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 38 0.057
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 38 0.057
AY358116-1|AAQ88483.1| 548|Homo sapiens LGI3 protein. 38 0.075
AJ487961-1|CAD32308.1| 548|Homo sapiens LGI1-like protein 4 pro... 38 0.075
AJ487518-1|CAD31786.1| 548|Homo sapiens leucine-rich glioma ina... 38 0.075
AF467956-1|AAM49554.1| 548|Homo sapiens LGI3 protein. 38 0.075
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 37 0.099
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 37 0.099
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 37 0.099
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 37 0.099
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 37 0.099
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 37 0.099
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 37 0.099
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 37 0.099
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 37 0.099
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 37 0.099
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 37 0.099
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 37 0.099
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 37 0.099
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 37 0.099
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 37 0.099
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 37 0.099
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 37 0.099
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 37 0.099
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 37 0.099
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 36 0.17
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 36 0.17
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 36 0.17
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 36 0.17
BC029858-1|AAH29858.1| 343|Homo sapiens leucine rich repeat con... 36 0.17
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 36 0.17
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 36 0.17
AK223535-1|BAD97255.1| 343|Homo sapiens leucine-rich B7 protein... 36 0.17
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 36 0.17
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 36 0.23
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 36 0.23
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 36 0.23
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 36 0.23
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 36 0.23
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 36 0.23
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 36 0.23
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 36 0.23
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 36 0.23
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 36 0.23
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 36 0.23
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 36 0.23
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 36 0.30
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 36 0.30
BC022500-1|AAH22500.1| 557|Homo sapiens leucine-rich, glioma in... 36 0.30
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 36 0.30
AY358885-1|AAQ89244.1| 557|Homo sapiens LGI1 protein. 36 0.30
AL358154-2|CAI14982.1| 557|Homo sapiens leucine-rich, glioma in... 36 0.30
AL358154-1|CAI14981.1| 291|Homo sapiens leucine-rich, glioma in... 36 0.30
AL157396-3|CAH73838.1| 557|Homo sapiens leucine-rich, glioma in... 36 0.30
AL157396-2|CAH73837.1| 291|Homo sapiens leucine-rich, glioma in... 36 0.30
AK000136-1|BAA90967.1| 187|Homo sapiens protein ( Homo sapiens ... 36 0.30
AF473548-1|AAM22074.1| 291|Homo sapiens leucine-rich glioma ina... 36 0.30
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 36 0.30
AF055636-1|AAC99316.1| 557|Homo sapiens leucine-rich glioma-ina... 36 0.30
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 36 0.30
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 36 0.30
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 35 0.40
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 35 0.40
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 35 0.40
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 35 0.40
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 35 0.40
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 35 0.40
BC034051-1|AAH34051.1| 1099|Homo sapiens serine/threonine kinase... 35 0.40
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 35 0.40
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 35 0.40
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 35 0.40
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 35 0.40
AF450267-1|AAL49726.1| 1099|Homo sapiens LKB1-interacting protei... 35 0.40
AB067485-1|BAB67791.1| 1013|Homo sapiens KIAA1898 protein protein. 35 0.40
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 35 0.40
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 35 0.53
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 35 0.53
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 35 0.53
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 35 0.53
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 35 0.53
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 35 0.53
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 35 0.53
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 35 0.53
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 35 0.53
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 35 0.53
AB033011-1|BAA86499.1| 403|Homo sapiens KIAA1185 protein protein. 35 0.53
U72508-1|AAC51638.1| 312|Homo sapiens B7 protein. 34 0.70
U47924-13|AAB51319.1| 312|Homo sapiens B7 protein. 34 0.70
BC050665-1|AAH50665.1| 523|Homo sapiens LRRC48 protein protein. 34 0.70
BC050419-1|AAH50419.1| 523|Homo sapiens LRRC48 protein protein. 34 0.70
BC047873-1|AAH47873.1| 523|Homo sapiens leucine rich repeat con... 34 0.70
BC040276-1|AAH40276.1| 457|Homo sapiens LRRC48 protein protein. 34 0.70
BC037831-1|AAH37831.1| 88|Homo sapiens LRRC8B protein protein. 34 0.70
BC030547-1|AAH30547.1| 647|Homo sapiens hypothetical protein DK... 34 0.70
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 34 0.92
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 34 0.92
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 34 0.92
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 34 0.92
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 34 0.92
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 34 0.92
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 34 0.92
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 34 0.92
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 34 0.92
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 34 0.92
AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens ... 34 0.92
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 34 0.92
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 34 0.92
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 34 0.92
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 33 1.2
BC027720-1|AAH27720.1| 740|Homo sapiens chromosome 20 open read... 33 1.2
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 33 1.6
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 33 1.6
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 33 1.6
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 33 1.6
BC087848-1|AAH87848.1| 261|Homo sapiens LGI4 protein protein. 33 1.6
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 33 1.6
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 33 1.6
BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat con... 33 1.6
BC030958-1|AAH30958.1| 322|Homo sapiens epiphycan protein. 33 1.6
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 33 1.6
BC009436-1|AAH09436.1| 610|Homo sapiens Unknown (protein for IM... 33 1.6
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 33 1.6
AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein. 33 1.6
AY358121-1|AAQ88488.1| 261|Homo sapiens LGI4 protein. 33 1.6
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 33 1.6
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 33 1.6
AJ487959-1|CAD32306.1| 537|Homo sapiens LGI1-like protein 3 pro... 33 1.6
AJ487519-1|CAD31787.1| 537|Homo sapiens leucine-rich glioma ina... 33 1.6
AF467954-1|AAM49552.1| 537|Homo sapiens LGI4 protein. 33 1.6
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 33 1.6
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 33 1.6
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 33 1.6
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 33 1.6
AB209379-1|BAD92616.1| 245|Homo sapiens hypothetical protein DK... 33 1.6
BC119649-1|AAI19650.1| 257|Homo sapiens leucine rich repeat con... 33 2.1
BC119648-1|AAI19649.1| 257|Homo sapiens leucine rich repeat con... 33 2.1
BC087849-1|AAH87849.1| 259|Homo sapiens LRRC3B protein protein. 33 2.1
BC067784-1|AAH67784.1| 259|Homo sapiens leucine rich repeat con... 33 2.1
BC040656-1|AAH40656.1| 259|Homo sapiens LRRC3B protein protein. 33 2.1
AY358282-1|AAQ88649.1| 259|Homo sapiens NLVD195 protein. 33 2.1
AY358120-1|AAQ88487.1| 257|Homo sapiens LLR protein protein. 33 2.1
AY061857-1|AAL35741.1| 257|Homo sapiens leucine-rich repeat dom... 33 2.1
AF396933-1|AAK84157.1| 259|Homo sapiens LRP15 protein. 33 2.1
AB058646-1|BAB40229.1| 257|Homo sapiens LRRC3 protein. 33 2.1
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 32 2.8
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 32 2.8
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 32 2.8
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 32 2.8
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 32 2.8
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 32 2.8
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 32 2.8
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 32 3.7
BC109112-1|AAI09113.1| 811|Homo sapiens TLR10 protein protein. 32 3.7
AL118505-1|CAI42165.1| 740|Homo sapiens chromosome 20 open read... 32 3.7
AL035461-2|CAI23479.1| 740|Homo sapiens chromosome 20 open read... 32 3.7
AK172833-1|BAD18798.1| 287|Homo sapiens protein ( Homo sapiens ... 32 3.7
AK091588-1|BAC03702.1| 213|Homo sapiens protein ( Homo sapiens ... 32 3.7
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 31 4.9
BC109111-1|AAI09112.1| 811|Homo sapiens TLR10 protein protein. 31 4.9
BC089406-1|AAH89406.1| 811|Homo sapiens TLR10 protein protein. 31 4.9
BC074943-1|AAH74943.1| 332|Homo sapiens opticin protein. 31 4.9
BC074942-1|AAH74942.1| 332|Homo sapiens opticin protein. 31 4.9
AY358300-1|AAQ88667.1| 811|Homo sapiens TLR10 protein. 31 4.9
AY077681-1|AAL78286.1| 332|Homo sapiens opticin protein. 31 4.9
AL391817-3|CAI17035.1| 332|Homo sapiens opticin protein. 31 4.9
AJ133790-1|CAB53459.1| 332|Homo sapiens opticin protein. 31 4.9
AF296673-1|AAK26744.1| 811|Homo sapiens toll-like receptor 10 p... 31 4.9
AF161702-1|AAD45900.1| 332|Homo sapiens oculoglycan protein. 31 4.9
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 31 6.5
U59111-1|AAC50945.1| 322|Homo sapiens dermatan sulfate proteogl... 31 6.5
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 31 6.5
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 31 6.5
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 31 6.5
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 31 6.5
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 31 6.5
Z22965-1|CAA80538.1| 86|Homo sapiens T-cell antigen receptor a... 31 8.6
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 31 8.6
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 31 8.6
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 31 8.6
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 31 8.6
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 31 8.6
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 31 8.6
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 31 8.6
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 31 8.6
>BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein.
Length = 1367
Score = 105 bits (251), Expect = 3e-22
Identities = 67/218 (30%), Positives = 104/218 (47%), Gaps = 2/218 (0%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXX 75
++EQ K+ + N +T IPG + + ++ +L + KN I +
Sbjct: 202 VLEQLSGLKEFWMDAN--RLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLL 259
Query: 76 XXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG 135
P IG+LKN+ L + N L L IG L +E C+ ++ +P IG
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 136 KLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
+LT L TF A N L+ +P E+ S + L L +N++ETLP+ M M L NL +NR
Sbjct: 320 QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNR 379
Query: 196 LEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
L+ P S K ++L + L+ NQ LI E ++T
Sbjct: 380 LKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSET 417
Score = 81.8 bits (193), Expect = 4e-15
Identities = 51/195 (26%), Positives = 84/195 (43%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K L L+ +I E+P L+ C + L L N ++ P
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQ 105
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P I N K L + S NP++ L L L + N L+ +P +LT+L
Sbjct: 106 EFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFDRLTKLQI 165
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
R N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P
Sbjct: 166 LELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGF 225
Query: 203 ILKCKELMFLQLNSN 217
I K+L +L ++ N
Sbjct: 226 IGSLKQLTYLDVSKN 240
Score = 73.7 bits (173), Expect = 9e-13
Identities = 52/212 (24%), Positives = 87/212 (41%), Gaps = 1/212 (0%)
Query: 7 FIRENHILALIEQAI-AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
++ N I L +Q + +LSL ++T +P + + + L + KN I FP
Sbjct: 52 YLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENI 111
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P L NL L L+ L L L KL+
Sbjct: 112 KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFDRLTKLQILELREN 171
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
LK +PK + +LTQL+ NE +PE + L+ L+ ++ N++ +P + +
Sbjct: 172 QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQ 231
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L + ++ N +E I C+ L L L+SN
Sbjct: 232 LTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/134 (29%), Positives = 65/134 (48%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N ++L L+L N L L I +L L ++ G++E P+ I L
Sbjct: 62 PKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ + L L L L + +E LP DR+T L LR N+L+ P ++
Sbjct: 122 ASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFDRLTKLQILELRENQLKMLPKTMN 181
Query: 205 KCKELMFLQLNSNQ 218
+ +L L L SN+
Sbjct: 182 RLTQLERLDLGSNE 195
Score = 62.1 bits (144), Expect = 3e-09
Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 1/185 (0%)
Query: 35 ITEIPGLLYTCLE-VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
+ ++P ++T + +E LYL N+I P + P I NL N
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLIN 93
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L++S N + I + + L + + ++P +L L L+ +
Sbjct: 94 LRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFL 153
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P L KL+ L L NQ++ LP TM+R+T L +L +N + P + + L
Sbjct: 154 PANFDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFW 213
Query: 214 LNSNQ 218
+++N+
Sbjct: 214 MDANR 218
Score = 58.8 bits (136), Expect = 3e-08
Identities = 52/204 (25%), Positives = 80/204 (39%), Gaps = 2/204 (0%)
Query: 15 ALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXX 74
A I I ++ +S NG I E P + C + + N IS P
Sbjct: 86 ASIANLINLRELDVSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQL 143
Query: 75 XXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI 134
P L L L L N L +L + L +LE E+P+ +
Sbjct: 144 YLNDAFLEFLPANFDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVL 203
Query: 135 GKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+L+ L F N L IP + SL +L +L + N IE + + + L L +N
Sbjct: 204 EQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+Q P +I K + L+++ NQ
Sbjct: 264 SLQQLPETIGSLKNITTLKIDENQ 287
Score = 58.4 bits (135), Expect = 4e-08
Identities = 43/188 (22%), Positives = 74/188 (39%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
I+++P L + LYL+ + P P + L L
Sbjct: 127 ISKLPDGFSQLLNLTQLYLNDAFLEFLPANFDRLTKLQILELRENQLKMLPKTMNRLTQL 186
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
L+L N + + L L+ FW + L IP IG L QL N ++ +
Sbjct: 187 ERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVE 246
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E +++ L+ L L +N ++ LP+T+ + + + N+L P SI + L
Sbjct: 247 EGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDC 306
Query: 215 NSNQEHAL 222
+ N+ AL
Sbjct: 307 SFNEVEAL 314
Score = 50.8 bits (116), Expect = 8e-06
Identities = 37/178 (20%), Positives = 73/178 (41%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSI 318
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 1/147 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIKYTDEAT 230
+ +L L+L NQ L K + T
Sbjct: 158 DRLTKLQILELRENQLKMLPKTMNRLT 184
>BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 105 bits (251), Expect = 3e-22
Identities = 67/218 (30%), Positives = 104/218 (47%), Gaps = 2/218 (0%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXX 75
++EQ K+ + N +T IPG + + ++ +L + KN I +
Sbjct: 202 VLEQLSGLKEFWMDAN--RLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLL 259
Query: 76 XXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG 135
P IG+LKN+ L + N L L IG L +E C+ ++ +P IG
Sbjct: 260 LSSNSLQQLPEPIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 136 KLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
+LT L TF A N L+ +P E+ S + L L +N++ETLP+ M M L NL +NR
Sbjct: 320 QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNR 379
Query: 196 LEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
L+ P S K ++L + L+ NQ LI E ++T
Sbjct: 380 LKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSET 417
Score = 84.6 bits (200), Expect = 5e-16
Identities = 52/195 (26%), Positives = 85/195 (43%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K L L+ +I E+P L+ C + L L N ++ P
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQ 105
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P I N K L + S NP++ L L L + N L+ +P G+LT+L
Sbjct: 106 EFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQI 165
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
R N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P
Sbjct: 166 LELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGF 225
Query: 203 ILKCKELMFLQLNSN 217
I K+L +L ++ N
Sbjct: 226 IGSLKQLTYLDVSKN 240
Score = 76.6 bits (180), Expect = 1e-13
Identities = 53/212 (25%), Positives = 88/212 (41%), Gaps = 1/212 (0%)
Query: 7 FIRENHILALIEQAI-AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
++ N I L +Q + +LSL ++T +P + + + L + KN I FP
Sbjct: 52 YLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENI 111
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P L NL L L+ L L G L KL+
Sbjct: 112 KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN 171
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
LK +PK + +LTQL+ NE +PE + L+ L+ ++ N++ +P + +
Sbjct: 172 QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQ 231
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L + ++ N +E I C+ L L L+SN
Sbjct: 232 LTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Score = 62.1 bits (144), Expect = 3e-09
Identities = 39/134 (29%), Positives = 64/134 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N ++L L+L N L L I +L L ++ G++E P+ I L
Sbjct: 62 PKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ + L L L L + +E LP R+T L LR N+L+ P ++
Sbjct: 122 ASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMN 181
Query: 205 KCKELMFLQLNSNQ 218
+ +L L L SN+
Sbjct: 182 RLTQLERLDLGSNE 195
Score = 61.7 bits (143), Expect = 4e-09
Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 1/185 (0%)
Query: 35 ITEIPGLLYTCLE-VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
+ ++P ++T + +E LYL N+I P + P I NL N
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLIN 93
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L++S N + I + + L + + ++P +L L L+ +
Sbjct: 94 LRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFL 153
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P L KL+ L L NQ++ LP TM+R+T L +L +N + P + + L
Sbjct: 154 PANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFW 213
Query: 214 LNSNQ 218
+++N+
Sbjct: 214 MDANR 218
Score = 60.9 bits (141), Expect = 7e-09
Identities = 53/204 (25%), Positives = 80/204 (39%), Gaps = 2/204 (0%)
Query: 15 ALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXX 74
A I I ++ +S NG I E P + C + + N IS P
Sbjct: 86 ASIANLINLRELDVSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQL 143
Query: 75 XXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI 134
P G L L L L N L +L + L +LE E+P+ +
Sbjct: 144 YLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVL 203
Query: 135 GKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+L+ L F N L IP + SL +L +L + N IE + + + L L +N
Sbjct: 204 EQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+Q P I K + L+++ NQ
Sbjct: 264 SLQQLPEPIGSLKNITTLKIDENQ 287
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/188 (22%), Positives = 73/188 (38%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
I+++P L + LYL+ + P P + L L
Sbjct: 127 ISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQL 186
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
L+L N + + L L+ FW + L IP IG L QL N ++ +
Sbjct: 187 ERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVE 246
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E +++ L+ L L +N ++ LP+ + + + + N+L P SI + L
Sbjct: 247 EGISTCENLQDLLLSSNSLQQLPEPIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDC 306
Query: 215 NSNQEHAL 222
+ N+ AL
Sbjct: 307 SFNEVEAL 314
Score = 50.8 bits (116), Expect = 8e-06
Identities = 37/178 (20%), Positives = 73/178 (41%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI
Sbjct: 261 SSNSLQQLPEPIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSI 318
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 1/147 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIKYTDEAT 230
+ +L L+L NQ L K + T
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNRLT 184
>BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein.
Length = 633
Score = 105 bits (251), Expect = 3e-22
Identities = 67/218 (30%), Positives = 104/218 (47%), Gaps = 2/218 (0%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXX 75
++EQ K+ + N +T IPG + + ++ +L + KN I +
Sbjct: 202 VLEQLSGLKEFWMDAN--RLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLL 259
Query: 76 XXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG 135
P IG+LKN+ L + N L L IG L +E C+ ++ +P IG
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 136 KLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
+LT L TF A N L+ +P E+ S + L L +N++ETLP+ M M L NL +NR
Sbjct: 320 QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNR 379
Query: 196 LEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
L+ P S K ++L + L+ NQ LI E ++T
Sbjct: 380 LKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSET 417
Score = 84.6 bits (200), Expect = 5e-16
Identities = 52/195 (26%), Positives = 85/195 (43%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K L L+ +I E+P L+ C + L L N ++ P
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQ 105
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P I N K L + S NP++ L L L + N L+ +P G+LT+L
Sbjct: 106 EFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQI 165
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
R N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P
Sbjct: 166 LELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGF 225
Query: 203 ILKCKELMFLQLNSN 217
I K+L +L ++ N
Sbjct: 226 IGSLKQLTYLDVSKN 240
Score = 76.6 bits (180), Expect = 1e-13
Identities = 53/212 (25%), Positives = 88/212 (41%), Gaps = 1/212 (0%)
Query: 7 FIRENHILALIEQAI-AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
++ N I L +Q + +LSL ++T +P + + + L + KN I FP
Sbjct: 52 YLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENI 111
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P L NL L L+ L L G L KL+
Sbjct: 112 KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN 171
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
LK +PK + +LTQL+ NE +PE + L+ L+ ++ N++ +P + +
Sbjct: 172 QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQ 231
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L + ++ N +E I C+ L L L+SN
Sbjct: 232 LTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Score = 62.1 bits (144), Expect = 3e-09
Identities = 39/134 (29%), Positives = 64/134 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N ++L L+L N L L I +L L ++ G++E P+ I L
Sbjct: 62 PKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ + L L L L + +E LP R+T L LR N+L+ P ++
Sbjct: 122 ASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMN 181
Query: 205 KCKELMFLQLNSNQ 218
+ +L L L SN+
Sbjct: 182 RLTQLERLDLGSNE 195
Score = 61.7 bits (143), Expect = 4e-09
Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 1/185 (0%)
Query: 35 ITEIPGLLYTCLE-VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
+ ++P ++T + +E LYL N+I P + P I NL N
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLIN 93
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L++S N + I + + L + + ++P +L L L+ +
Sbjct: 94 LRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFL 153
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P L KL+ L L NQ++ LP TM+R+T L +L +N + P + + L
Sbjct: 154 PANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFW 213
Query: 214 LNSNQ 218
+++N+
Sbjct: 214 MDANR 218
Score = 61.7 bits (143), Expect = 4e-09
Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 2/204 (0%)
Query: 15 ALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXX 74
A I I ++ +S NG I E P + C + + N IS P
Sbjct: 86 ASIANLINLRELDVSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQL 143
Query: 75 XXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI 134
P G L L L L N L +L + L +LE E+P+ +
Sbjct: 144 YLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVL 203
Query: 135 GKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+L+ L F N L IP + SL +L +L + N IE + + + L L +N
Sbjct: 204 EQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+Q P +I K + L+++ NQ
Sbjct: 264 SLQQLPETIGSLKNITTLKIDENQ 287
Score = 58.4 bits (135), Expect = 4e-08
Identities = 43/188 (22%), Positives = 74/188 (39%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
I+++P L + LYL+ + P P + L L
Sbjct: 127 ISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQL 186
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
L+L N + + L L+ FW + L IP IG L QL N ++ +
Sbjct: 187 ERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVE 246
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E +++ L+ L L +N ++ LP+T+ + + + N+L P SI + L
Sbjct: 247 EGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDC 306
Query: 215 NSNQEHAL 222
+ N+ AL
Sbjct: 307 SFNEVEAL 314
Score = 50.8 bits (116), Expect = 8e-06
Identities = 37/178 (20%), Positives = 73/178 (41%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSI 318
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 1/147 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIKYTDEAT 230
+ +L L+L NQ L K + T
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNRLT 184
>AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein
protein.
Length = 1412
Score = 105 bits (251), Expect = 3e-22
Identities = 67/218 (30%), Positives = 104/218 (47%), Gaps = 2/218 (0%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXX 75
++EQ K+ + N +T IPG + + ++ +L + KN I +
Sbjct: 202 VLEQLSGLKEFWMDAN--RLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLL 259
Query: 76 XXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG 135
P IG+LKN+ L + N L L IG L +E C+ ++ +P IG
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 136 KLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
+LT L TF A N L+ +P E+ S + L L +N++ETLP+ M M L NL +NR
Sbjct: 320 QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNR 379
Query: 196 LEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
L+ P S K ++L + L+ NQ LI E ++T
Sbjct: 380 LKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSET 417
Score = 84.6 bits (200), Expect = 5e-16
Identities = 52/195 (26%), Positives = 85/195 (43%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K L L+ +I E+P L+ C + L L N ++ P
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQ 105
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P I N K L + S NP++ L L L + N L+ +P G+LT+L
Sbjct: 106 EFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQI 165
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
R N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P
Sbjct: 166 LELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGF 225
Query: 203 ILKCKELMFLQLNSN 217
I K+L +L ++ N
Sbjct: 226 IGSLKQLTYLDVSKN 240
Score = 76.6 bits (180), Expect = 1e-13
Identities = 53/212 (25%), Positives = 88/212 (41%), Gaps = 1/212 (0%)
Query: 7 FIRENHILALIEQAI-AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
++ N I L +Q + +LSL ++T +P + + + L + KN I FP
Sbjct: 52 YLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENI 111
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P L NL L L+ L L G L KL+
Sbjct: 112 KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN 171
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
LK +PK + +LTQL+ NE +PE + L+ L+ ++ N++ +P + +
Sbjct: 172 QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQ 231
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L + ++ N +E I C+ L L L+SN
Sbjct: 232 LTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Score = 62.1 bits (144), Expect = 3e-09
Identities = 39/134 (29%), Positives = 64/134 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N ++L L+L N L L I +L L ++ G++E P+ I L
Sbjct: 62 PKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ + L L L L + +E LP R+T L LR N+L+ P ++
Sbjct: 122 ASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMN 181
Query: 205 KCKELMFLQLNSNQ 218
+ +L L L SN+
Sbjct: 182 RLTQLERLDLGSNE 195
Score = 61.7 bits (143), Expect = 4e-09
Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 1/185 (0%)
Query: 35 ITEIPGLLYTCLE-VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
+ ++P ++T + +E LYL N+I P + P I NL N
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLIN 93
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L++S N + I + + L + + ++P +L L L+ +
Sbjct: 94 LRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFL 153
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P L KL+ L L NQ++ LP TM+R+T L +L +N + P + + L
Sbjct: 154 PANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFW 213
Query: 214 LNSNQ 218
+++N+
Sbjct: 214 MDANR 218
Score = 61.7 bits (143), Expect = 4e-09
Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 2/204 (0%)
Query: 15 ALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXX 74
A I I ++ +S NG I E P + C + + N IS P
Sbjct: 86 ASIANLINLRELDVSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQL 143
Query: 75 XXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI 134
P G L L L L N L +L + L +LE E+P+ +
Sbjct: 144 YLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVL 203
Query: 135 GKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+L+ L F N L IP + SL +L +L + N IE + + + L L +N
Sbjct: 204 EQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+Q P +I K + L+++ NQ
Sbjct: 264 SLQQLPETIGSLKNITTLKIDENQ 287
Score = 58.4 bits (135), Expect = 4e-08
Identities = 43/188 (22%), Positives = 74/188 (39%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
I+++P L + LYL+ + P P + L L
Sbjct: 127 ISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQL 186
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
L+L N + + L L+ FW + L IP IG L QL N ++ +
Sbjct: 187 ERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVE 246
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E +++ L+ L L +N ++ LP+T+ + + + N+L P SI + L
Sbjct: 247 EGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDC 306
Query: 215 NSNQEHAL 222
+ N+ AL
Sbjct: 307 SFNEVEAL 314
Score = 50.8 bits (116), Expect = 8e-06
Identities = 37/178 (20%), Positives = 73/178 (41%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSI 318
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 1/147 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIKYTDEAT 230
+ +L L+L NQ L K + T
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNRLT 184
>AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting protein
ERBIN protein.
Length = 1371
Score = 105 bits (251), Expect = 3e-22
Identities = 67/218 (30%), Positives = 104/218 (47%), Gaps = 2/218 (0%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXX 75
++EQ K+ + N +T IPG + + ++ +L + KN I +
Sbjct: 202 VLEQLSGLKEFWMDAN--RLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLL 259
Query: 76 XXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG 135
P IG+LKN+ L + N L L IG L +E C+ ++ +P IG
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 136 KLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
+LT L TF A N L+ +P E+ S + L L +N++ETLP+ M M L NL +NR
Sbjct: 320 QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNR 379
Query: 196 LEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
L+ P S K ++L + L+ NQ LI E ++T
Sbjct: 380 LKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSET 417
Score = 84.6 bits (200), Expect = 5e-16
Identities = 52/195 (26%), Positives = 85/195 (43%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K L L+ +I E+P L+ C + L L N ++ P
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQ 105
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P I N K L + S NP++ L L L + N L+ +P G+LT+L
Sbjct: 106 EFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQI 165
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
R N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P
Sbjct: 166 LELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGF 225
Query: 203 ILKCKELMFLQLNSN 217
I K+L +L ++ N
Sbjct: 226 IGSLKQLTYLDVSKN 240
Score = 76.6 bits (180), Expect = 1e-13
Identities = 53/212 (25%), Positives = 88/212 (41%), Gaps = 1/212 (0%)
Query: 7 FIRENHILALIEQAI-AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
++ N I L +Q + +LSL ++T +P + + + L + KN I FP
Sbjct: 52 YLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENI 111
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P L NL L L+ L L G L KL+
Sbjct: 112 KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN 171
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
LK +PK + +LTQL+ NE +PE + L+ L+ ++ N++ +P + +
Sbjct: 172 QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQ 231
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L + ++ N +E I C+ L L L+SN
Sbjct: 232 LTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Score = 62.1 bits (144), Expect = 3e-09
Identities = 39/134 (29%), Positives = 64/134 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N ++L L+L N L L I +L L ++ G++E P+ I L
Sbjct: 62 PKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ + L L L L + +E LP R+T L LR N+L+ P ++
Sbjct: 122 ASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMN 181
Query: 205 KCKELMFLQLNSNQ 218
+ +L L L SN+
Sbjct: 182 RLTQLERLDLGSNE 195
Score = 61.7 bits (143), Expect = 4e-09
Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 1/185 (0%)
Query: 35 ITEIPGLLYTCLE-VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
+ ++P ++T + +E LYL N+I P + P I NL N
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLIN 93
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L++S N + I + + L + + ++P +L L L+ +
Sbjct: 94 LRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFL 153
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P L KL+ L L NQ++ LP TM+R+T L +L +N + P + + L
Sbjct: 154 PANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFW 213
Query: 214 LNSNQ 218
+++N+
Sbjct: 214 MDANR 218
Score = 61.7 bits (143), Expect = 4e-09
Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 2/204 (0%)
Query: 15 ALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXX 74
A I I ++ +S NG I E P + C + + N IS P
Sbjct: 86 ASIANLINLRELDVSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQL 143
Query: 75 XXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI 134
P G L L L L N L +L + L +LE E+P+ +
Sbjct: 144 YLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVL 203
Query: 135 GKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+L+ L F N L IP + SL +L +L + N IE + + + L L +N
Sbjct: 204 EQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+Q P +I K + L+++ NQ
Sbjct: 264 SLQQLPETIGSLKNITTLKIDENQ 287
Score = 58.4 bits (135), Expect = 4e-08
Identities = 43/188 (22%), Positives = 74/188 (39%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
I+++P L + LYL+ + P P + L L
Sbjct: 127 ISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQL 186
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
L+L N + + L L+ FW + L IP IG L QL N ++ +
Sbjct: 187 ERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVE 246
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E +++ L+ L L +N ++ LP+T+ + + + N+L P SI + L
Sbjct: 247 EGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDC 306
Query: 215 NSNQEHAL 222
+ N+ AL
Sbjct: 307 SFNEVEAL 314
Score = 50.8 bits (116), Expect = 8e-06
Identities = 37/178 (20%), Positives = 73/178 (41%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSI 318
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 1/147 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIKYTDEAT 230
+ +L L+L NQ L K + T
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNRLT 184
>AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein.
Length = 1371
Score = 105 bits (251), Expect = 3e-22
Identities = 67/218 (30%), Positives = 104/218 (47%), Gaps = 2/218 (0%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXX 75
++EQ K+ + N +T IPG + + ++ +L + KN I +
Sbjct: 202 VLEQLSGLKEFWMDAN--RLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLL 259
Query: 76 XXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG 135
P IG+LKN+ L + N L L IG L +E C+ ++ +P IG
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 136 KLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
+LT L TF A N L+ +P E+ S + L L +N++ETLP+ M M L NL +NR
Sbjct: 320 QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNR 379
Query: 196 LEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
L+ P S K ++L + L+ NQ LI E ++T
Sbjct: 380 LKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSET 417
Score = 84.6 bits (200), Expect = 5e-16
Identities = 52/195 (26%), Positives = 85/195 (43%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K L L+ +I E+P L+ C + L L N ++ P
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQ 105
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P I N K L + S NP++ L L L + N L+ +P G+LT+L
Sbjct: 106 EFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQI 165
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
R N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P
Sbjct: 166 LELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGF 225
Query: 203 ILKCKELMFLQLNSN 217
I K+L +L ++ N
Sbjct: 226 IGSLKQLTYLDVSKN 240
Score = 76.6 bits (180), Expect = 1e-13
Identities = 53/212 (25%), Positives = 88/212 (41%), Gaps = 1/212 (0%)
Query: 7 FIRENHILALIEQAI-AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
++ N I L +Q + +LSL ++T +P + + + L + KN I FP
Sbjct: 52 YLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENI 111
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P L NL L L+ L L G L KL+
Sbjct: 112 KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN 171
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
LK +PK + +LTQL+ NE +PE + L+ L+ ++ N++ +P + +
Sbjct: 172 QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQ 231
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L + ++ N +E I C+ L L L+SN
Sbjct: 232 LTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Score = 62.1 bits (144), Expect = 3e-09
Identities = 39/134 (29%), Positives = 64/134 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N ++L L+L N L L I +L L ++ G++E P+ I L
Sbjct: 62 PKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ + L L L L + +E LP R+T L LR N+L+ P ++
Sbjct: 122 ASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMN 181
Query: 205 KCKELMFLQLNSNQ 218
+ +L L L SN+
Sbjct: 182 RLTQLERLDLGSNE 195
Score = 61.7 bits (143), Expect = 4e-09
Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 1/185 (0%)
Query: 35 ITEIPGLLYTCLE-VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
+ ++P ++T + +E LYL N+I P + P I NL N
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLIN 93
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L++S N + I + + L + + ++P +L L L+ +
Sbjct: 94 LRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFL 153
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P L KL+ L L NQ++ LP TM+R+T L +L +N + P + + L
Sbjct: 154 PANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFW 213
Query: 214 LNSNQ 218
+++N+
Sbjct: 214 MDANR 218
Score = 61.7 bits (143), Expect = 4e-09
Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 2/204 (0%)
Query: 15 ALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXX 74
A I I ++ +S NG I E P + C + + N IS P
Sbjct: 86 ASIANLINLRELDVSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQL 143
Query: 75 XXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI 134
P G L L L L N L +L + L +LE E+P+ +
Sbjct: 144 YLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVL 203
Query: 135 GKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+L+ L F N L IP + SL +L +L + N IE + + + L L +N
Sbjct: 204 EQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+Q P +I K + L+++ NQ
Sbjct: 264 SLQQLPETIGSLKNITTLKIDENQ 287
Score = 58.4 bits (135), Expect = 4e-08
Identities = 43/188 (22%), Positives = 74/188 (39%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
I+++P L + LYL+ + P P + L L
Sbjct: 127 ISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQL 186
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
L+L N + + L L+ FW + L IP IG L QL N ++ +
Sbjct: 187 ERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVE 246
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E +++ L+ L L +N ++ LP+T+ + + + N+L P SI + L
Sbjct: 247 EGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDC 306
Query: 215 NSNQEHAL 222
+ N+ AL
Sbjct: 307 SFNEVEAL 314
Score = 50.8 bits (116), Expect = 8e-06
Identities = 37/178 (20%), Positives = 73/178 (41%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSI 318
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 1/147 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIKYTDEAT 230
+ +L L+L NQ L K + T
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNRLT 184
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 103 bits (247), Expect = 1e-21
Identities = 67/218 (30%), Positives = 103/218 (47%), Gaps = 2/218 (0%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXX 75
++EQ K+ + N +T IPG + + ++ +L + KN I +
Sbjct: 202 VLEQLSGLKEFWMDAN--RLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLL 259
Query: 76 XXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG 135
P IG LKN+ L + N L L IG L +E C+ ++ +P IG
Sbjct: 260 LSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 136 KLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
+LT L TF A N L+ +P E+ S + L L +N++ETLP+ M M L NL +NR
Sbjct: 320 QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNR 379
Query: 196 LEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
L+ P S K ++L + L+ NQ LI E ++T
Sbjct: 380 LKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSET 417
Score = 84.6 bits (200), Expect = 5e-16
Identities = 52/195 (26%), Positives = 85/195 (43%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K L L+ +I E+P L+ C + L L N ++ P
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQ 105
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P I N K L + S NP++ L L L + N L+ +P G+LT+L
Sbjct: 106 EFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQI 165
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
R N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P
Sbjct: 166 LELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGF 225
Query: 203 ILKCKELMFLQLNSN 217
I K+L +L ++ N
Sbjct: 226 IGSLKQLTYLDVSKN 240
Score = 76.6 bits (180), Expect = 1e-13
Identities = 53/212 (25%), Positives = 88/212 (41%), Gaps = 1/212 (0%)
Query: 7 FIRENHILALIEQAI-AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
++ N I L +Q + +LSL ++T +P + + + L + KN I FP
Sbjct: 52 YLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENI 111
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P L NL L L+ L L G L KL+
Sbjct: 112 KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN 171
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
LK +PK + +LTQL+ NE +PE + L+ L+ ++ N++ +P + +
Sbjct: 172 QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQ 231
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L + ++ N +E I C+ L L L+SN
Sbjct: 232 LTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Score = 62.1 bits (144), Expect = 3e-09
Identities = 39/134 (29%), Positives = 64/134 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N ++L L+L N L L I +L L ++ G++E P+ I L
Sbjct: 62 PKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ + L L L L + +E LP R+T L LR N+L+ P ++
Sbjct: 122 ASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMN 181
Query: 205 KCKELMFLQLNSNQ 218
+ +L L L SN+
Sbjct: 182 RLTQLERLDLGSNE 195
Score = 61.7 bits (143), Expect = 4e-09
Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 1/185 (0%)
Query: 35 ITEIPGLLYTCLE-VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
+ ++P ++T + +E LYL N+I P + P I NL N
Sbjct: 34 LEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLIN 93
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L++S N + I + + L + + ++P +L L L+ +
Sbjct: 94 LRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFL 153
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P L KL+ L L NQ++ LP TM+R+T L +L +N + P + + L
Sbjct: 154 PANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFW 213
Query: 214 LNSNQ 218
+++N+
Sbjct: 214 MDANR 218
Score = 60.9 bits (141), Expect = 7e-09
Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 2/204 (0%)
Query: 15 ALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXX 74
A I I ++ +S NG I E P + C + + N IS P
Sbjct: 86 ASIANLINLRELDVSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQL 143
Query: 75 XXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI 134
P G L L L L N L +L + L +LE E+P+ +
Sbjct: 144 YLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVL 203
Query: 135 GKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+L+ L F N L IP + SL +L +L + N IE + + + L L +N
Sbjct: 204 EQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+Q P +I K + L+++ NQ
Sbjct: 264 SLQQLPETIGLLKNITTLKIDENQ 287
Score = 58.0 bits (134), Expect = 5e-08
Identities = 43/188 (22%), Positives = 74/188 (39%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
I+++P L + LYL+ + P P + L L
Sbjct: 127 ISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQL 186
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
L+L N + + L L+ FW + L IP IG L QL N ++ +
Sbjct: 187 ERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVE 246
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E +++ L+ L L +N ++ LP+T+ + + + N+L P SI + L
Sbjct: 247 EGISTCENLQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDC 306
Query: 215 NSNQEHAL 222
+ N+ AL
Sbjct: 307 SFNEVEAL 314
Score = 48.4 bits (110), Expect = 4e-05
Identities = 36/178 (20%), Positives = 72/178 (40%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N L+ +PE + L + L ++ NQ+ LPD++ + ++ + N +E PSSI
Sbjct: 261 SSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSI 318
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 1/147 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIKYTDEAT 230
+ +L L+L NQ L K + T
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNRLT 184
>AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 407 QSKALIPLQTEAHPET 422
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 236 MLVYLDMSKNR 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 258 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 291
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 146 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 205
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 206 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 265
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 266 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 326 LHSLRTLAVDEN 337
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 67 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 126
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 127 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 186
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 187 KLAQLERLDLGNNEFGELPEVLDQ 210
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 163 GRLVKLRILELRENHLKTLPK 183
>AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 402 QSKALIPLQTEAHPET 417
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 231 MLVYLDMSKNR 241
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 253 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 286
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 201 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 261 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 321 LHSLRTLAVDEN 332
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 62 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 122 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 181
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 182 KLAQLERLDLGNNEFGELPEVLDQ 205
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 158 GRLVKLRILELRENHLKTLPK 178
>AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 407 QSKALIPLQTEAHPET 422
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 236 MLVYLDMSKNR 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 258 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 291
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 146 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 205
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 206 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 265
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 266 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 326 LHSLRTLAVDEN 337
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 67 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 126
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 127 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 186
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 187 KLAQLERLDLGNNEFGELPEVLDQ 210
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 163 GRLVKLRILELRENHLKTLPK 183
>AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 402 QSKALIPLQTEAHPET 417
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 231 MLVYLDMSKNR 241
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 253 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 286
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 201 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 261 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 321 LHSLRTLAVDEN 332
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 62 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 122 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 181
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 182 KLAQLERLDLGNNEFGELPEVLDQ 205
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 158 GRLVKLRILELRENHLKTLPK 178
>AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 407 QSKALIPLQTEAHPET 422
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 236 MLVYLDMSKNR 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 258 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 291
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 146 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 205
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 206 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 265
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 266 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 326 LHSLRTLAVDEN 337
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 67 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 126
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 127 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 186
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 187 KLAQLERLDLGNNEFGELPEVLDQ 210
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 163 GRLVKLRILELRENHLKTLPK 183
>AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 402 QSKALIPLQTEAHPET 417
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 231 MLVYLDMSKNR 241
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 253 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 286
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 201 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 261 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 321 LHSLRTLAVDEN 332
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 62 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 122 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 181
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 182 KLAQLERLDLGNNEFGELPEVLDQ 205
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 158 GRLVKLRILELRENHLKTLPK 178
>AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 407 QSKALIPLQTEAHPET 422
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 236 MLVYLDMSKNR 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 258 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 291
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 146 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 205
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 206 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 265
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 266 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 326 LHSLRTLAVDEN 337
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 67 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 126
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 127 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 186
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 187 KLAQLERLDLGNNEFGELPEVLDQ 210
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 163 GRLVKLRILELRENHLKTLPK 183
>AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 402 QSKALIPLQTEAHPET 417
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 231 MLVYLDMSKNR 241
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 253 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 286
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 201 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 261 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 321 LHSLRTLAVDEN 332
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 62 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 122 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 181
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 182 KLAQLERLDLGNNEFGELPEVLDQ 205
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 158 GRLVKLRILELRENHLKTLPK 178
>AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 407 QSKALIPLQTEAHPET 422
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 236 MLVYLDMSKNR 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 258 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 291
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 146 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 205
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 206 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 265
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 266 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 325
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 326 LHSLRTLAVDEN 337
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 67 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 126
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 127 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 186
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 187 KLAQLERLDLGNNEFGELPEVLDQ 210
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 163 GRLVKLRILELRENHLKTLPK 183
>AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein.
Length = 1537
Score = 98.3 bits (234), Expect = 4e-20
Identities = 63/196 (32%), Positives = 92/196 (46%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 157
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 158 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 218 QEHALIKYTDEATTQT 233
Q ALI EA +T
Sbjct: 402 QSKALIPLQTEAHPET 417
Score = 88.2 bits (209), Expect = 4e-17
Identities = 56/191 (29%), Positives = 86/191 (45%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 208 ELMFLQLNSNQ 218
L++L ++ N+
Sbjct: 231 MLVYLDMSKNR 241
Score = 81.4 bits (192), Expect = 5e-15
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 207 KELMFLQLNSNQEHAL---IKYTDEATTQTSDSN 237
+ L L L+SN L I + TT D N
Sbjct: 253 EALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDN 286
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/192 (22%), Positives = 81/192 (42%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L LN + +P +++ L L +N + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELP 200
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ ++NL L + N L VL IG L+ L ++ ++ + +I L+
Sbjct: 201 EVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLL 260
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L+ +P+ + L KL L +++NQ+ LP+T+ ++ L + N LE PS+I
Sbjct: 261 SSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGY 320
Query: 206 CKELMFLQLNSN 217
L L ++ N
Sbjct: 321 LHSLRTLAVDEN 332
Score = 58.0 bits (134), Expect = 5e-08
Identities = 41/144 (28%), Positives = 66/144 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 62 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 121
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N + +P+ T L L L L + +E LP R+ L LR N L+ P S+
Sbjct: 122 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMH 181
Query: 205 KCKELMFLQLNSNQEHALIKYTDE 228
K +L L L +N+ L + D+
Sbjct: 182 KLAQLERLDLGNNEFGELPEVLDQ 205
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Score = 40.7 bits (91), Expect = 0.008
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 204 LKCKELMFLQLNSNQEHALIK 224
+ +L L+L N L K
Sbjct: 158 GRLVKLRILELRENHLKTLPK 178
>BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat
containing 2 protein.
Length = 371
Score = 94.3 bits (224), Expect = 6e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 1/189 (0%)
Query: 30 LNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG 89
L+G TE+P L + Y+ I + P P EIG
Sbjct: 105 LSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIG 164
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGN 148
LKNL LN+ +N L + PE+GD E LE C+ + L E+P E+ L Q+ N
Sbjct: 165 CLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISAN 224
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 208
+ ++P + ++ L+WL + +N + LP +DR+ L L N+L P S+L K+
Sbjct: 225 KFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKK 284
Query: 209 LMFLQLNSN 217
L L ++ +
Sbjct: 285 LTLLVVSGD 293
Score = 46.4 bits (105), Expect = 2e-04
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ NLK + +++S N + + + + L+ + L ++P++I +L +L +F
Sbjct: 207 PFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFL 266
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLE 197
N+L +P M +L KL L + + + LP + D T L +L +N ++
Sbjct: 267 LYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPID 320
Score = 35.9 bits (79), Expect = 0.23
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 2/104 (1%)
Query: 114 LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI 173
L+K+E R +PK+ GK + F G +P+ + LR + N I
Sbjct: 76 LDKIERNTLTR--QSSLPKDRGKRSSAFVFELSGEHWTELPDSLKEQTHLREWYISNTLI 133
Query: 174 ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+ +P + A+ +L N++ P+ I K L L + N
Sbjct: 134 QIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFN 177
>AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat
containing 2 variant protein.
Length = 371
Score = 94.3 bits (224), Expect = 6e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 1/189 (0%)
Query: 30 LNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG 89
L+G TE+P L + Y+ I + P P EIG
Sbjct: 105 LSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIG 164
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGN 148
LKNL LN+ +N L + PE+GD E LE C+ + L E+P E+ L Q+ N
Sbjct: 165 CLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISAN 224
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 208
+ ++P + ++ L+WL + +N + LP +DR+ L L N+L P S+L K+
Sbjct: 225 KFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKK 284
Query: 209 LMFLQLNSN 217
L L ++ +
Sbjct: 285 LTLLVVSGD 293
Score = 46.4 bits (105), Expect = 2e-04
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ NLK + +++S N + + + + L+ + L ++P++I +L +L +F
Sbjct: 207 PFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFL 266
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLE 197
N+L +P M +L KL L + + + LP + D T L +L +N ++
Sbjct: 267 LYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPID 320
Score = 35.9 bits (79), Expect = 0.23
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 2/104 (1%)
Query: 114 LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI 173
L+K+E R +PK+ GK + F G +P+ + LR + N I
Sbjct: 76 LDKIERNTLTR--QSSLPKDRGKRSSAFVFELSGEHWTELPDSLKEQTHLREWYISNTLI 133
Query: 174 ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+ +P + A+ +L N++ P+ I K L L + N
Sbjct: 134 QIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFN 177
>AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens
cDNA FLJ25079 fis, clone CBL07055. ).
Length = 371
Score = 94.3 bits (224), Expect = 6e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 1/189 (0%)
Query: 30 LNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG 89
L+G TE+P L + Y+ I + P P EIG
Sbjct: 105 LSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIG 164
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGN 148
LKNL LN+ +N L + PE+GD E LE C+ + L E+P E+ L Q+ N
Sbjct: 165 CLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISAN 224
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 208
+ ++P + ++ L+WL + +N + LP +DR+ L L N+L P S+L K+
Sbjct: 225 KFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKK 284
Query: 209 LMFLQLNSN 217
L L ++ +
Sbjct: 285 LTLLVVSGD 293
Score = 46.4 bits (105), Expect = 2e-04
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ NLK + +++S N + + + + L+ + L ++P++I +L +L +F
Sbjct: 207 PFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFL 266
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLE 197
N+L +P M +L KL L + + + LP + D T L +L +N ++
Sbjct: 267 LYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPID 320
Score = 35.9 bits (79), Expect = 0.23
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 2/104 (1%)
Query: 114 LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI 173
L+K+E R +PK+ GK + F G +P+ + LR + N I
Sbjct: 76 LDKIERNTLTR--QSSLPKDRGKRSSAFVFELSGEHWTELPDSLKEQTHLREWYISNTLI 133
Query: 174 ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+ +P + A+ +L N++ P+ I K L L + N
Sbjct: 134 QIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFN 177
>AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich
repeat-containing 2 protein protein.
Length = 371
Score = 93.9 bits (223), Expect = 8e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 1/189 (0%)
Query: 30 LNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG 89
L+G TE+P L + Y+ I + P P EIG
Sbjct: 105 LSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQEMRILDLPKNQISHLPAEIG 164
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGN 148
LKNL LN+ +N L + PE+GD E LE C+ + L E+P E+ L Q+ N
Sbjct: 165 CLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISAN 224
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 208
+ ++P + ++ L+WL + +N + LP +DR+ L L N+L P S+L K+
Sbjct: 225 KFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKK 284
Query: 209 LMFLQLNSN 217
L L ++ +
Sbjct: 285 LTLLVVSGD 293
Score = 46.4 bits (105), Expect = 2e-04
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ NLK + +++S N + + + + L+ + L ++P++I +L +L +F
Sbjct: 207 PFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFL 266
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLE 197
N+L +P M +L KL L + + + LP + D T L +L +N ++
Sbjct: 267 LYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPID 320
Score = 33.9 bits (74), Expect = 0.92
Identities = 24/104 (23%), Positives = 42/104 (40%), Gaps = 2/104 (1%)
Query: 114 LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI 173
L+K+E R +PK+ GK + F G +P+ + LR + N I
Sbjct: 76 LDKIERNTLTR--QSSLPKDRGKRSSAFVFELSGEHWTELPDSLKEQTHLREWYISNTLI 133
Query: 174 ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+ +P + + +L N++ P+ I K L L + N
Sbjct: 134 QIIPTYIQLFQEMRILDLPKNQISHLPAEIGCLKNLKELNVGFN 177
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 87.0 bits (206), Expect = 9e-17
Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 2/195 (1%)
Query: 8 IRENHILALIEQAIAKKKSR-LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+ EN + +L + KK R L L ++ EIP ++Y + LYL N+I+ +
Sbjct: 153 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 212
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P EIG L NL+ L++++N L L EIG+ ++
Sbjct: 213 NLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 272
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTA 185
L ++P IG L+ L G R N L IP + + L L LENN I TLP++ + +
Sbjct: 273 LLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVK 332
Query: 186 LVHCNLRNNRLEQFP 200
L L N + +P
Sbjct: 333 LNSLTLARNCFQLYP 347
Score = 83.4 bits (197), Expect = 1e-15
Identities = 50/192 (26%), Positives = 90/192 (46%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 126 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 246 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 206 CKELMFLQLNSN 217
C L L L +N
Sbjct: 306 CSALEELNLENN 317
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 454
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 455 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 205 KCKELMFLQLNSNQE-HAL 222
+ L L LN N H+L
Sbjct: 515 TLENLEELYLNDNPNLHSL 533
Score = 77.0 bits (181), Expect = 1e-13
Identities = 49/177 (27%), Positives = 79/177 (44%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+L+ +T +P L ++ L L NK+ P +
Sbjct: 151 LALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKD 210
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I NL L L++ N + L EIG+L L L+ +PKEIG TQ+ +
Sbjct: 211 IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQH 270
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
NEL +P+ + +L+ L L L N++ +P ++ + +AL NL NN + P S+L
Sbjct: 271 NELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 327
Score = 74.5 bits (175), Expect = 5e-13
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 3/187 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
IT + + ++ L + +NKI P E P EIGN +
Sbjct: 204 ITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 263
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
NL+L +N L L IG+L L L IP+ + K + L+ N + T+P
Sbjct: 264 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 323
Query: 155 EE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL-KCKELMF 211
E ++SL KL LTL N + P + + + N+ +NR+ + P I + K L
Sbjct: 324 ESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSK 383
Query: 212 LQLNSNQ 218
L + NQ
Sbjct: 384 LNMKDNQ 390
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 5/197 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
SRL L ++ IP L C +E L L N IS P E
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 345
Query: 86 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 141
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 202 SILKCKELMFLQLNSNQ 218
I K+L L L +NQ
Sbjct: 466 EIAYLKDLQKLVLTNNQ 482
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/127 (28%), Positives = 64/127 (50%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 100 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 159
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219
Query: 212 LQLNSNQ 218
L + N+
Sbjct: 220 LSIRENK 226
Score = 60.9 bits (141), Expect = 7e-09
Identities = 43/150 (28%), Positives = 67/150 (44%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L L L L N L L E+G L L + L +P + L +L
Sbjct: 116 PSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLD 175
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
R N+L+ IP + L L L L N+I T+ + ++ L ++R N+++Q P+ I
Sbjct: 176 LRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIG 235
Query: 205 KCKELMFLQLNSNQEHALIKYTDEATTQTS 234
+ L+ L + NQ L K T T+
Sbjct: 236 ELCNLITLDVAHNQLEHLPKEIGNCTQITN 265
Score = 58.8 bits (136), Expect = 3e-08
Identities = 45/191 (23%), Positives = 76/191 (39%), Gaps = 2/191 (1%)
Query: 28 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 479
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 205
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 480 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 539
Query: 206 CKELMFLQLNS 216
C +L + + +
Sbjct: 540 CSKLSIMSIEN 550
Score = 41.9 bits (94), Expect = 0.003
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 5/201 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L E+ ++P + + L L N++S P P
Sbjct: 264 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 323
Query: 86 TEI-GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEI-GKLTQLD 141
+ +L L +L L+ N L P G + + N + +IP I + L
Sbjct: 324 ESLLSSLVKLNSLTLARNCFQ-LYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLS 382
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L ++P + + + L L NQ+ +P+ + + +L L NN L++ P
Sbjct: 383 KLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPH 442
Query: 202 SILKCKELMFLQLNSNQEHAL 222
+ ++L L L N+ +L
Sbjct: 443 GLGNLRKLRELDLEENKLESL 463
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 87.0 bits (206), Expect = 9e-17
Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 2/195 (1%)
Query: 8 IRENHILALIEQAIAKKKSR-LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+ EN + +L + KK R L L ++ EIP ++Y + LYL N+I+ +
Sbjct: 153 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 212
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P EIG L NL+ L++++N L L EIG+ ++
Sbjct: 213 NLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 272
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTA 185
L ++P IG L+ L G R N L IP + + L L LENN I TLP++ + +
Sbjct: 273 LLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVK 332
Query: 186 LVHCNLRNNRLEQFP 200
L L N + +P
Sbjct: 333 LNSLTLARNCFQLYP 347
Score = 83.4 bits (197), Expect = 1e-15
Identities = 50/192 (26%), Positives = 90/192 (46%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 126 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 246 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 206 CKELMFLQLNSN 217
C L L L +N
Sbjct: 306 CSALEELNLENN 317
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 454
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 455 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 205 KCKELMFLQLNSNQE-HAL 222
+ L L LN N H+L
Sbjct: 515 TLENLEELYLNDNPNLHSL 533
Score = 77.0 bits (181), Expect = 1e-13
Identities = 49/177 (27%), Positives = 79/177 (44%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+L+ +T +P L ++ L L NK+ P +
Sbjct: 151 LALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKD 210
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I NL L L++ N + L EIG+L L L+ +PKEIG TQ+ +
Sbjct: 211 IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQH 270
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
NEL +P+ + +L+ L L L N++ +P ++ + +AL NL NN + P S+L
Sbjct: 271 NELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 327
Score = 74.5 bits (175), Expect = 5e-13
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 3/187 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
IT + + ++ L + +NKI P E P EIGN +
Sbjct: 204 ITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 263
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
NL+L +N L L IG+L L L IP+ + K + L+ N + T+P
Sbjct: 264 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 323
Query: 155 EE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL-KCKELMF 211
E ++SL KL LTL N + P + + + N+ +NR+ + P I + K L
Sbjct: 324 ESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSK 383
Query: 212 LQLNSNQ 218
L + NQ
Sbjct: 384 LNMKDNQ 390
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 5/197 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
SRL L ++ IP L C +E L L N IS P E
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 345
Query: 86 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 141
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 202 SILKCKELMFLQLNSNQ 218
I K+L L L +NQ
Sbjct: 466 EIAYLKDLQKLVLTNNQ 482
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/127 (28%), Positives = 64/127 (50%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 100 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 159
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219
Query: 212 LQLNSNQ 218
L + N+
Sbjct: 220 LSIRENK 226
Score = 60.9 bits (141), Expect = 7e-09
Identities = 43/150 (28%), Positives = 67/150 (44%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L L L L N L L E+G L L + L +P + L +L
Sbjct: 116 PSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLD 175
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
R N+L+ IP + L L L L N+I T+ + ++ L ++R N+++Q P+ I
Sbjct: 176 LRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIG 235
Query: 205 KCKELMFLQLNSNQEHALIKYTDEATTQTS 234
+ L+ L + NQ L K T T+
Sbjct: 236 ELCNLITLDVAHNQLEHLPKEIGNCTQITN 265
Score = 58.8 bits (136), Expect = 3e-08
Identities = 45/191 (23%), Positives = 76/191 (39%), Gaps = 2/191 (1%)
Query: 28 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 479
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 205
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 480 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 539
Query: 206 CKELMFLQLNS 216
C +L + + +
Sbjct: 540 CSKLSIMSIEN 550
Score = 41.9 bits (94), Expect = 0.003
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 5/201 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L E+ ++P + + L L N++S P P
Sbjct: 264 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 323
Query: 86 TEI-GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEI-GKLTQLD 141
+ +L L +L L+ N L P G + + N + +IP I + L
Sbjct: 324 ESLLSSLVKLNSLTLARNCFQ-LYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLS 382
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L ++P + + + L L NQ+ +P+ + + +L L NN L++ P
Sbjct: 383 KLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPH 442
Query: 202 SILKCKELMFLQLNSNQEHAL 222
+ ++L L L N+ +L
Sbjct: 443 GLGNLRKLRELDLEENKLESL 463
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 87.0 bits (206), Expect = 9e-17
Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 2/195 (1%)
Query: 8 IRENHILALIEQAIAKKKSR-LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+ EN + +L + KK R L L ++ EIP ++Y + LYL N+I+ +
Sbjct: 153 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 212
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P EIG L NL+ L++++N L L EIG+ ++
Sbjct: 213 NLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 272
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTA 185
L ++P IG L+ L G R N L IP + + L L LENN I TLP++ + +
Sbjct: 273 LLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVK 332
Query: 186 LVHCNLRNNRLEQFP 200
L L N + +P
Sbjct: 333 LNSLTLARNCFQLYP 347
Score = 83.4 bits (197), Expect = 1e-15
Identities = 50/192 (26%), Positives = 90/192 (46%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 126 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 246 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 206 CKELMFLQLNSN 217
C L L L +N
Sbjct: 306 CSALEELNLENN 317
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 454
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 455 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 205 KCKELMFLQLNSNQE-HAL 222
+ L L LN N H+L
Sbjct: 515 TLENLEELYLNDNPNLHSL 533
Score = 77.0 bits (181), Expect = 1e-13
Identities = 49/177 (27%), Positives = 79/177 (44%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+L+ +T +P L ++ L L NK+ P +
Sbjct: 151 LALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKD 210
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I NL L L++ N + L EIG+L L L+ +PKEIG TQ+ +
Sbjct: 211 IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQH 270
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
NEL +P+ + +L+ L L L N++ +P ++ + +AL NL NN + P S+L
Sbjct: 271 NELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 327
Score = 74.5 bits (175), Expect = 5e-13
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 3/187 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
IT + + ++ L + +NKI P E P EIGN +
Sbjct: 204 ITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 263
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
NL+L +N L L IG+L L L IP+ + K + L+ N + T+P
Sbjct: 264 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 323
Query: 155 EE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL-KCKELMF 211
E ++SL KL LTL N + P + + + N+ +NR+ + P I + K L
Sbjct: 324 ESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSK 383
Query: 212 LQLNSNQ 218
L + NQ
Sbjct: 384 LNMKDNQ 390
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 5/197 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
SRL L ++ IP L C +E L L N IS P E
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 345
Query: 86 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 141
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 202 SILKCKELMFLQLNSNQ 218
I K+L L L +NQ
Sbjct: 466 EIAYLKDLQKLVLTNNQ 482
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/127 (28%), Positives = 64/127 (50%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 100 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 159
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219
Query: 212 LQLNSNQ 218
L + N+
Sbjct: 220 LSIRENK 226
Score = 60.9 bits (141), Expect = 7e-09
Identities = 43/150 (28%), Positives = 67/150 (44%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L L L L N L L E+G L L + L +P + L +L
Sbjct: 116 PSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLD 175
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
R N+L+ IP + L L L L N+I T+ + ++ L ++R N+++Q P+ I
Sbjct: 176 LRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIG 235
Query: 205 KCKELMFLQLNSNQEHALIKYTDEATTQTS 234
+ L+ L + NQ L K T T+
Sbjct: 236 ELCNLITLDVAHNQLEHLPKEIGNCTQITN 265
Score = 58.8 bits (136), Expect = 3e-08
Identities = 45/191 (23%), Positives = 76/191 (39%), Gaps = 2/191 (1%)
Query: 28 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 479
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 205
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 480 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 539
Query: 206 CKELMFLQLNS 216
C +L + + +
Sbjct: 540 CSKLSIMSIEN 550
Score = 41.9 bits (94), Expect = 0.003
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 5/201 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L E+ ++P + + L L N++S P P
Sbjct: 264 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 323
Query: 86 TEI-GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEI-GKLTQLD 141
+ +L L +L L+ N L P G + + N + +IP I + L
Sbjct: 324 ESLLSSLVKLNSLTLARNCFQ-LYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLS 382
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L ++P + + + L L NQ+ +P+ + + +L L NN L++ P
Sbjct: 383 KLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPH 442
Query: 202 SILKCKELMFLQLNSNQEHAL 222
+ ++L L L N+ +L
Sbjct: 443 GLGNLRKLRELDLEENKLESL 463
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 87.0 bits (206), Expect = 9e-17
Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 2/195 (1%)
Query: 8 IRENHILALIEQAIAKKKSR-LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+ EN + +L + KK R L L ++ EIP ++Y + LYL N+I+ +
Sbjct: 153 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 212
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P EIG L NL+ L++++N L L EIG+ ++
Sbjct: 213 NLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 272
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTA 185
L ++P IG L+ L G R N L IP + + L L LENN I TLP++ + +
Sbjct: 273 LLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVK 332
Query: 186 LVHCNLRNNRLEQFP 200
L L N + +P
Sbjct: 333 LNSLTLARNCFQLYP 347
Score = 83.4 bits (197), Expect = 1e-15
Identities = 50/192 (26%), Positives = 90/192 (46%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 126 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 246 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 206 CKELMFLQLNSN 217
C L L L +N
Sbjct: 306 CSALEELNLENN 317
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 454
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 455 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 205 KCKELMFLQLNSNQE-HAL 222
+ L L LN N H+L
Sbjct: 515 TLENLEELYLNDNPNLHSL 533
Score = 77.0 bits (181), Expect = 1e-13
Identities = 49/177 (27%), Positives = 79/177 (44%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+L+ +T +P L ++ L L NK+ P +
Sbjct: 151 LALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKD 210
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I NL L L++ N + L EIG+L L L+ +PKEIG TQ+ +
Sbjct: 211 IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQH 270
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
NEL +P+ + +L+ L L L N++ +P ++ + +AL NL NN + P S+L
Sbjct: 271 NELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 327
Score = 74.5 bits (175), Expect = 5e-13
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 3/187 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
IT + + ++ L + +NKI P E P EIGN +
Sbjct: 204 ITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 263
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
NL+L +N L L IG+L L L IP+ + K + L+ N + T+P
Sbjct: 264 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 323
Query: 155 EE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL-KCKELMF 211
E ++SL KL LTL N + P + + + N+ +NR+ + P I + K L
Sbjct: 324 ESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSK 383
Query: 212 LQLNSNQ 218
L + NQ
Sbjct: 384 LNMKDNQ 390
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 5/197 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
SRL L ++ IP L C +E L L N IS P E
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 345
Query: 86 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 141
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 202 SILKCKELMFLQLNSNQ 218
I K+L L L +NQ
Sbjct: 466 EIAYLKDLQKLVLTNNQ 482
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/127 (28%), Positives = 64/127 (50%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 100 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 159
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219
Query: 212 LQLNSNQ 218
L + N+
Sbjct: 220 LSIRENK 226
Score = 60.9 bits (141), Expect = 7e-09
Identities = 43/150 (28%), Positives = 67/150 (44%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L L L L N L L E+G L L + L +P + L +L
Sbjct: 116 PSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLD 175
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
R N+L+ IP + L L L L N+I T+ + ++ L ++R N+++Q P+ I
Sbjct: 176 LRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIG 235
Query: 205 KCKELMFLQLNSNQEHALIKYTDEATTQTS 234
+ L+ L + NQ L K T T+
Sbjct: 236 ELCNLITLDVAHNQLEHLPKEIGNCTQITN 265
Score = 58.8 bits (136), Expect = 3e-08
Identities = 45/191 (23%), Positives = 76/191 (39%), Gaps = 2/191 (1%)
Query: 28 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 479
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 205
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 480 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 539
Query: 206 CKELMFLQLNS 216
C +L + + +
Sbjct: 540 CSKLSIMSIEN 550
Score = 41.9 bits (94), Expect = 0.003
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 5/201 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L E+ ++P + + L L N++S P P
Sbjct: 264 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 323
Query: 86 TEI-GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEI-GKLTQLD 141
+ +L L +L L+ N L P G + + N + +IP I + L
Sbjct: 324 ESLLSSLVKLNSLTLARNCFQ-LYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLS 382
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L ++P + + + L L NQ+ +P+ + + +L L NN L++ P
Sbjct: 383 KLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPH 442
Query: 202 SILKCKELMFLQLNSNQEHAL 222
+ ++L L L N+ +L
Sbjct: 443 GLGNLRKLRELDLEENKLESL 463
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 87.0 bits (206), Expect = 9e-17
Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 2/195 (1%)
Query: 8 IRENHILALIEQAIAKKKSR-LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+ EN + +L + KK R L L ++ EIP ++Y + LYL N+I+ +
Sbjct: 155 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 214
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P EIG L NL+ L++++N L L EIG+ ++
Sbjct: 215 NLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 274
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTA 185
L ++P IG L+ L G R N L IP + + L L LENN I TLP++ + +
Sbjct: 275 LLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVK 334
Query: 186 LVHCNLRNNRLEQFP 200
L L N + +P
Sbjct: 335 LNSLTLARNCFQLYP 349
Score = 83.4 bits (197), Expect = 1e-15
Identities = 50/192 (26%), Positives = 90/192 (46%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 128 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 187
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 188 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 247
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 248 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 307
Query: 206 CKELMFLQLNSN 217
C L L L +N
Sbjct: 308 CSALEELNLENN 319
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 397 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 456
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 457 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 516
Query: 205 KCKELMFLQLNSNQE-HAL 222
+ L L LN N H+L
Sbjct: 517 TLENLEELYLNDNPNLHSL 535
Score = 77.0 bits (181), Expect = 1e-13
Identities = 49/177 (27%), Positives = 79/177 (44%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+L+ +T +P L ++ L L NK+ P +
Sbjct: 153 LALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKD 212
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I NL L L++ N + L EIG+L L L+ +PKEIG TQ+ +
Sbjct: 213 IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQH 272
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
NEL +P+ + +L+ L L L N++ +P ++ + +AL NL NN + P S+L
Sbjct: 273 NELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 329
Score = 74.5 bits (175), Expect = 5e-13
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 3/187 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
IT + + ++ L + +NKI P E P EIGN +
Sbjct: 206 ITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 265
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
NL+L +N L L IG+L L L IP+ + K + L+ N + T+P
Sbjct: 266 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 325
Query: 155 EE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL-KCKELMF 211
E ++SL KL LTL N + P + + + N+ +NR+ + P I + K L
Sbjct: 326 ESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSK 385
Query: 212 LQLNSNQ 218
L + NQ
Sbjct: 386 LNMKDNQ 392
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 5/197 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
SRL L ++ IP L C +E L L N IS P E
Sbjct: 289 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 347
Query: 86 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 141
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 348 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 407
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 408 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 467
Query: 202 SILKCKELMFLQLNSNQ 218
I K+L L L +NQ
Sbjct: 468 EIAYLKDLQKLVLTNNQ 484
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/127 (28%), Positives = 64/127 (50%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 102 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 161
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 162 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 221
Query: 212 LQLNSNQ 218
L + N+
Sbjct: 222 LSIRENK 228
Score = 60.9 bits (141), Expect = 7e-09
Identities = 43/150 (28%), Positives = 67/150 (44%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L L L L N L L E+G L L + L +P + L +L
Sbjct: 118 PSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLD 177
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
R N+L+ IP + L L L L N+I T+ + ++ L ++R N+++Q P+ I
Sbjct: 178 LRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIG 237
Query: 205 KCKELMFLQLNSNQEHALIKYTDEATTQTS 234
+ L+ L + NQ L K T T+
Sbjct: 238 ELCNLITLDVAHNQLEHLPKEIGNCTQITN 267
Score = 58.8 bits (136), Expect = 3e-08
Identities = 45/191 (23%), Positives = 76/191 (39%), Gaps = 2/191 (1%)
Query: 28 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 362 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 421
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 422 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 481
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 205
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 482 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPLELAL 541
Query: 206 CKELMFLQLNS 216
C +L + + +
Sbjct: 542 CSKLSIMSIEN 552
Score = 41.9 bits (94), Expect = 0.003
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 5/201 (2%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+ L L E+ ++P + + L L N++S P P
Sbjct: 266 TNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP 325
Query: 86 TEI-GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEI-GKLTQLD 141
+ +L L +L L+ N L P G + + N + +IP I + L
Sbjct: 326 ESLLSSLVKLNSLTLARNCFQ-LYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLS 384
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L ++P + + + L L NQ+ +P+ + + +L L NN L++ P
Sbjct: 385 KLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPH 444
Query: 202 SILKCKELMFLQLNSNQEHAL 222
+ ++L L L N+ +L
Sbjct: 445 GLGNLRKLRELDLEENKLESL 465
>BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein.
Length = 239
Score = 84.6 bits (200), Expect = 5e-16
Identities = 47/133 (35%), Positives = 71/133 (53%), Gaps = 1/133 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P IG L +L+L+ N L VL EI +L+KLE N L+E+P G+L+ L T
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN+L +P ++ SL L + L NQI ++PD++ + ++ NL N++ Q I
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGEL-QVIELNLNQNQISQISVKIS 173
Query: 205 KCKELMFLQLNSN 217
C L L+L N
Sbjct: 174 CCPRLKILRLEEN 186
Score = 61.3 bits (142), Expect = 5e-09
Identities = 30/88 (34%), Positives = 47/88 (53%)
Query: 131 PKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCN 190
P IGK T L + N+L +P+E+ +L KL L+L NN + LP T +++AL +
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 191 LRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L N+L P + + L + L+ NQ
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQ 142
Score = 55.6 bits (128), Expect = 3e-07
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Query: 115 EKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQ 172
+K F GL E P ++ KLT L T N+++++P + L+ L+L NN+
Sbjct: 14 QKTGVFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNK 73
Query: 173 IETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ LPD + + L +L NN L + PS+ + L L L+ NQ AL
Sbjct: 74 LTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGAL 123
Score = 35.9 bits (79), Expect = 0.23
Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 5/137 (3%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
KK LSLN + E+P ++ L L N++ P +
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQIR 144
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWC--NRIGLKEIPKEIGKLTQL 140
P +G L+ ++ LNL+ N ++ + +I +L+ N + L +P+ I +Q+
Sbjct: 145 SIPDSVGELQ-VIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSDSQI 203
Query: 141 DTFGARGN--ELKTIPE 155
GN E+K + E
Sbjct: 204 CLLAVEGNLFEIKKLRE 220
>AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens
cDNA FLJ37572 fis, clone BRCOC2002751, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 239
Score = 84.6 bits (200), Expect = 5e-16
Identities = 47/133 (35%), Positives = 71/133 (53%), Gaps = 1/133 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P IG L +L+L+ N L VL EI +L+KLE N L+E+P G+L+ L T
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN+L +P ++ SL L + L NQI ++PD++ + ++ NL N++ Q I
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGEL-QVIELNLNQNQISQISVKIS 173
Query: 205 KCKELMFLQLNSN 217
C L L+L N
Sbjct: 174 CCPRLKILRLEEN 186
Score = 61.3 bits (142), Expect = 5e-09
Identities = 30/88 (34%), Positives = 47/88 (53%)
Query: 131 PKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCN 190
P IGK T L + N+L +P+E+ +L KL L+L NN + LP T +++AL +
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 191 LRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L N+L P + + L + L+ NQ
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQ 142
Score = 55.6 bits (128), Expect = 3e-07
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Query: 115 EKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQ 172
+K F GL E P ++ KLT L T N+++++P + L+ L+L NN+
Sbjct: 14 QKTGVFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNK 73
Query: 173 IETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ LPD + + L +L NN L + PS+ + L L L+ NQ AL
Sbjct: 74 LTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGAL 123
Score = 35.9 bits (79), Expect = 0.23
Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 5/137 (3%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
KK LSLN + E+P ++ L L N++ P +
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQIR 144
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWC--NRIGLKEIPKEIGKLTQL 140
P +G L+ ++ LNL+ N ++ + +I +L+ N + L +P+ I +Q+
Sbjct: 145 SIPDSVGELQ-VIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSDSQI 203
Query: 141 DTFGARGN--ELKTIPE 155
GN E+K + E
Sbjct: 204 CLLAVEGNLFEIKKLRE 220
>AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein.
Length = 239
Score = 84.6 bits (200), Expect = 5e-16
Identities = 47/133 (35%), Positives = 71/133 (53%), Gaps = 1/133 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P IG L +L+L+ N L VL EI +L+KLE N L+E+P G+L+ L T
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN+L +P ++ SL L + L NQI ++PD++ + ++ NL N++ Q I
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGEL-QVIELNLNQNQISQISVKIS 173
Query: 205 KCKELMFLQLNSN 217
C L L+L N
Sbjct: 174 CCPRLKILRLEEN 186
Score = 61.3 bits (142), Expect = 5e-09
Identities = 30/88 (34%), Positives = 47/88 (53%)
Query: 131 PKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCN 190
P IGK T L + N+L +P+E+ +L KL L+L NN + LP T +++AL +
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 191 LRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L N+L P + + L + L+ NQ
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQ 142
Score = 55.6 bits (128), Expect = 3e-07
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Query: 115 EKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQ 172
+K F GL E P ++ KLT L T N+++++P + L+ L+L NN+
Sbjct: 14 QKTGVFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNK 73
Query: 173 IETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ LPD + + L +L NN L + PS+ + L L L+ NQ AL
Sbjct: 74 LTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGAL 123
Score = 35.9 bits (79), Expect = 0.23
Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 5/137 (3%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
KK LSLN + E+P ++ L L N++ P +
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQIR 144
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWC--NRIGLKEIPKEIGKLTQL 140
P +G L+ ++ LNL+ N ++ + +I +L+ N + L +P+ I +Q+
Sbjct: 145 SIPDSVGELQ-VIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSDSQI 203
Query: 141 DTFGARGN--ELKTIPE 155
GN E+K + E
Sbjct: 204 CLLAVEGNLFEIKKLRE 220
>BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 83.8 bits (198), Expect = 9e-16
Identities = 56/206 (27%), Positives = 89/206 (43%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQT 233
+L L+++ N+ L + E + T
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLT 292
Score = 81.8 bits (193), Expect = 4e-15
Identities = 57/212 (26%), Positives = 91/212 (42%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+ L L+ ++ E+P + +++ L L N+I P E
Sbjct: 35 ARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL L +L+ L N I L+ +P+ IG L L
Sbjct: 95 PEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLA 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ R N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P
Sbjct: 155 SLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQ 214
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
I K L+ L ++ N+ L + T+ T
Sbjct: 215 EIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 45/134 (33%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L+ L L+L N + L IG L L+ W + L E+P+EIG L L
Sbjct: 167 PDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLD 226
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE++ L L L + N +ET+PD + ++ L + NRL Q P ++
Sbjct: 227 VSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVG 286
Query: 205 KCKELMFLQLNSNQ 218
+C+ L L L NQ
Sbjct: 287 ECESLTELVLTENQ 300
Score = 78.6 bits (185), Expect = 3e-14
Identities = 58/196 (29%), Positives = 82/196 (41%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 215 NSNQEHALIKYTDEAT 230
N+ + +AT
Sbjct: 343 RDNRLTRIPAEVSQAT 358
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+G +++E+P + + L + +N++ P E P
Sbjct: 202 LWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDG 261
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L L +G+ E L L +PK IGKL +L A
Sbjct: 262 IGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADR 321
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L ++P+E+ L + +N++ +P + + T L ++ NRL P S+ K
Sbjct: 322 NKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPLSLTALK 381
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L+ NQ L+ + + T +
Sbjct: 382 -LKALWLSDNQSQPLLTFQTDTDYTTGE 408
>AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 83.8 bits (198), Expect = 9e-16
Identities = 56/206 (27%), Positives = 89/206 (43%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQT 233
+L L+++ N+ L + E + T
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLT 292
Score = 81.8 bits (193), Expect = 4e-15
Identities = 57/212 (26%), Positives = 91/212 (42%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+ L L+ ++ E+P + +++ L L N+I P E
Sbjct: 35 ARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL L +L+ L N I L+ +P+ IG L L
Sbjct: 95 PEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLA 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ R N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P
Sbjct: 155 SLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQ 214
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
I K L+ L ++ N+ L + T+ T
Sbjct: 215 EIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 45/134 (33%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L+ L L+L N + L IG L L+ W + L E+P+EIG L L
Sbjct: 167 PDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLD 226
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE++ L L L + N +ET+PD + ++ L + NRL Q P ++
Sbjct: 227 VSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVG 286
Query: 205 KCKELMFLQLNSNQ 218
+C+ L L L NQ
Sbjct: 287 ECESLTELVLTENQ 300
Score = 78.6 bits (185), Expect = 3e-14
Identities = 58/196 (29%), Positives = 82/196 (41%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 215 NSNQEHALIKYTDEAT 230
N+ + +AT
Sbjct: 343 RDNRLTRIPAEVSQAT 358
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+G +++E+P + + L + +N++ P E P
Sbjct: 202 LWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDG 261
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L L +G+ E L L +PK IGKL +L A
Sbjct: 262 IGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADR 321
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L ++P+E+ L + +N++ +P + + T L ++ NRL P S+ K
Sbjct: 322 NKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPLSLTALK 381
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L+ NQ L+ + + T +
Sbjct: 382 -LKALWLSDNQSQPLLTFQTDTDYTTGE 408
>AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 83.8 bits (198), Expect = 9e-16
Identities = 56/206 (27%), Positives = 89/206 (43%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQT 233
+L L+++ N+ L + E + T
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLT 292
Score = 81.8 bits (193), Expect = 4e-15
Identities = 57/212 (26%), Positives = 91/212 (42%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+ L L+ ++ E+P + +++ L L N+I P E
Sbjct: 35 ARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL L +L+ L N I L+ +P+ IG L L
Sbjct: 95 PEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLA 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ R N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P
Sbjct: 155 SLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQ 214
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
I K L+ L ++ N+ L + T+ T
Sbjct: 215 EIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 45/134 (33%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L+ L L+L N + L IG L L+ W + L E+P+EIG L L
Sbjct: 167 PDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLD 226
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE++ L L L + N +ET+PD + ++ L + NRL Q P ++
Sbjct: 227 VSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVG 286
Query: 205 KCKELMFLQLNSNQ 218
+C+ L L L NQ
Sbjct: 287 ECESLTELVLTENQ 300
Score = 78.6 bits (185), Expect = 3e-14
Identities = 58/196 (29%), Positives = 82/196 (41%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 215 NSNQEHALIKYTDEAT 230
N+ + +AT
Sbjct: 343 RDNRLTRIPAEVSQAT 358
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+G +++E+P + + L + +N++ P E P
Sbjct: 202 LWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDG 261
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L L +G+ E L L +PK IGKL +L A
Sbjct: 262 IGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADR 321
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L ++P+E+ L + +N++ +P + + T L ++ NRL P S+ K
Sbjct: 322 NKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPLSLTALK 381
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L+ NQ L+ + + T +
Sbjct: 382 -LKALWLSDNQSQPLLTFQTDTDYTTGE 408
>AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein
protein.
Length = 524
Score = 83.8 bits (198), Expect = 9e-16
Identities = 56/206 (27%), Positives = 89/206 (43%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQT 233
+L L+++ N+ L + E + T
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLT 292
Score = 81.8 bits (193), Expect = 4e-15
Identities = 57/212 (26%), Positives = 91/212 (42%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+ L L+ ++ E+P + +++ L L N+I P E
Sbjct: 35 ARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL L +L+ L N I L+ +P+ IG L L
Sbjct: 95 PEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLA 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ R N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P
Sbjct: 155 SLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQ 214
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
I K L+ L ++ N+ L + T+ T
Sbjct: 215 EIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 45/134 (33%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L+ L L+L N + L IG L L+ W + L E+P+EIG L L
Sbjct: 167 PDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLD 226
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE++ L L L + N +ET+PD + ++ L + NRL Q P ++
Sbjct: 227 VSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVG 286
Query: 205 KCKELMFLQLNSNQ 218
+C+ L L L NQ
Sbjct: 287 ECESLTELVLTENQ 300
Score = 78.6 bits (185), Expect = 3e-14
Identities = 58/196 (29%), Positives = 82/196 (41%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 215 NSNQEHALIKYTDEAT 230
N+ + +AT
Sbjct: 343 RDNRLTRIPAEVSQAT 358
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+G +++E+P + + L + +N++ P E P
Sbjct: 202 LWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDG 261
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L L +G+ E L L +PK IGKL +L A
Sbjct: 262 IGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADR 321
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L ++P+E+ L + +N++ +P + + T L ++ NRL P S+ K
Sbjct: 322 NKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPLSLTALK 381
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L+ NQ L+ + + T +
Sbjct: 382 -LKALWLSDNQSQPLLTFQTDTDYTTGE 408
>AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats
protein protein.
Length = 524
Score = 83.8 bits (198), Expect = 9e-16
Identities = 56/206 (27%), Positives = 89/206 (43%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQT 233
+L L+++ N+ L + E + T
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLT 292
Score = 81.8 bits (193), Expect = 4e-15
Identities = 57/212 (26%), Positives = 91/212 (42%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+ L L+ ++ E+P + +++ L L N+I P E
Sbjct: 35 ARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL L +L+ L N I L+ +P+ IG L L
Sbjct: 95 PEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLA 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ R N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P
Sbjct: 155 SLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQ 214
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQT 233
I K L+ L ++ N+ L + T+ T
Sbjct: 215 EIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Score = 81.4 bits (192), Expect = 5e-15
Identities = 45/134 (33%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L+ L L+L N + L IG L L+ W + L E+P+EIG L L
Sbjct: 167 PDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLD 226
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE++ L L L + N +ET+PD + ++ L + NRL Q P ++
Sbjct: 227 VSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVG 286
Query: 205 KCKELMFLQLNSNQ 218
+C+ L L L NQ
Sbjct: 287 ECESLTELVLTENQ 300
Score = 78.6 bits (185), Expect = 3e-14
Identities = 58/196 (29%), Positives = 82/196 (41%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 215 NSNQEHALIKYTDEAT 230
N+ + +AT
Sbjct: 343 RDNRLTRIPAEVSQAT 358
Score = 76.2 bits (179), Expect = 2e-13
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+G +++E+P + + L + +N++ P E P
Sbjct: 202 LWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDG 261
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L L +G+ E L L +PK IGKL +L A
Sbjct: 262 IGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADR 321
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L ++P+E+ L + +N++ +P + + T L ++ NRL P S+ K
Sbjct: 322 NKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPLSLTALK 381
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L+ NQ L+ + + T +
Sbjct: 382 -LKALWLSDNQSQPLLTFQTDTDYTTGE 408
>D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein.
Length = 1630
Score = 81.0 bits (191), Expect = 6e-15
Identities = 60/216 (27%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Query: 8 IRENHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+REN + +L + K +L L G ++ +P L + L+L +N++S P E
Sbjct: 158 LRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELG 217
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P E+G L L +L LS N L L IG L++L ++
Sbjct: 218 NLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNR 277
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+ + IG L N L +P + L KL L ++ N +E LP + AL
Sbjct: 278 LCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVAL 337
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+LR+NRL P + EL L + N+ +L
Sbjct: 338 SVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSL 373
Score = 77.8 bits (183), Expect = 6e-14
Identities = 53/197 (26%), Positives = 83/197 (42%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
++ L L+ ++ E+P + L + L L N+I P E
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL+ L L L N + L+ +P ++G L L
Sbjct: 95 PEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLV 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
T R N LK++P ++ L KL L L N +E LPDT+ + L L N+L P
Sbjct: 155 TLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPP 214
Query: 202 SILKCKELMFLQLNSNQ 218
+ + L+ L ++ N+
Sbjct: 215 ELGNLRRLVCLDVSENR 231
Score = 75.4 bits (177), Expect = 3e-13
Identities = 52/191 (27%), Positives = 81/191 (42%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ +I EIP + C +E N +S P P +
Sbjct: 87 LDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGD 146
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+GNL NLV L L N L L + L KLE L+ +P +G L L
Sbjct: 147 VGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDR 206
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P E+ +L +L L + N++E LP + + L L N L + P I + K
Sbjct: 207 NQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLK 266
Query: 208 ELMFLQLNSNQ 218
+L L+++ N+
Sbjct: 267 QLSILKVDQNR 277
Score = 73.3 bits (172), Expect = 1e-12
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +++ +P L + L + +N++ P E P
Sbjct: 202 LWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDG 261
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L + IGD E L L +P+ +GKLT+L
Sbjct: 262 IGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDR 321
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N L+ +P E+ L L+L +N++ LP + T L ++ NRL+ P ++
Sbjct: 322 NHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSLPFALTHL- 380
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L NQ ++++ E +T +
Sbjct: 381 NLKALWLAENQAQPMLRFQTEDDARTGE 408
Score = 71.3 bits (167), Expect = 5e-12
Identities = 61/249 (24%), Positives = 93/249 (37%), Gaps = 3/249 (1%)
Query: 31 NGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGN 90
+G ++ +P + HL L+ + P + P +
Sbjct: 113 SGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSF 172
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L L L+L N L VL +G L L W +R L +P E+G L +L N L
Sbjct: 173 LVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRL 232
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 210
+ +P E+ L L L L N + LPD + ++ L + NRL + +I C+ L
Sbjct: 233 EELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLS 292
Query: 211 FLQLNSNQEHALIKYTDEAT--TQTSDSNGSLASAMPSTSRVYGAQALALNATALRLPAA 268
L L N AL + + T T + L + P L+L L +
Sbjct: 293 ELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAV-LP 351
Query: 269 PEHQHPDPL 277
PE H L
Sbjct: 352 PELAHTTEL 360
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/138 (30%), Positives = 61/138 (44%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P L NL L LS N + L PE+ + +L +R + EIP+ I L+
Sbjct: 52 PKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIAD 111
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN L +P+ T L L L L + ++ LP + + LV LR N L+ P+S+
Sbjct: 112 FSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLS 171
Query: 205 KCKELMFLQLNSNQEHAL 222
+L L L N L
Sbjct: 172 FLVKLEQLDLGGNDLEVL 189
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/96 (28%), Positives = 45/96 (46%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+E+PK +L L G NE++ +P E+ + +L L + N I +P+++ AL
Sbjct: 48 LRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKAL 107
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ N L + P + + L L LN AL
Sbjct: 108 EIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQAL 143
>AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein.
Length = 1630
Score = 81.0 bits (191), Expect = 6e-15
Identities = 60/216 (27%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Query: 8 IRENHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+REN + +L + K +L L G ++ +P L + L+L +N++S P E
Sbjct: 158 LRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELG 217
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P E+G L L +L LS N L L IG L++L ++
Sbjct: 218 NLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNR 277
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+ + IG L N L +P + L KL L ++ N +E LP + AL
Sbjct: 278 LCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVAL 337
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+LR+NRL P + EL L + N+ +L
Sbjct: 338 SVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSL 373
Score = 77.8 bits (183), Expect = 6e-14
Identities = 53/197 (26%), Positives = 83/197 (42%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
++ L L+ ++ E+P + L + L L N+I P E
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL+ L L L N + L+ +P ++G L L
Sbjct: 95 PEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLV 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
T R N LK++P ++ L KL L L N +E LPDT+ + L L N+L P
Sbjct: 155 TLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPP 214
Query: 202 SILKCKELMFLQLNSNQ 218
+ + L+ L ++ N+
Sbjct: 215 ELGNLRRLVCLDVSENR 231
Score = 75.4 bits (177), Expect = 3e-13
Identities = 52/191 (27%), Positives = 81/191 (42%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ +I EIP + C +E N +S P P +
Sbjct: 87 LDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGD 146
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+GNL NLV L L N L L + L KLE L+ +P +G L L
Sbjct: 147 VGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDR 206
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P E+ +L +L L + N++E LP + + L L N L + P I + K
Sbjct: 207 NQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLK 266
Query: 208 ELMFLQLNSNQ 218
+L L+++ N+
Sbjct: 267 QLSILKVDQNR 277
Score = 73.3 bits (172), Expect = 1e-12
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +++ +P L + L + +N++ P E P
Sbjct: 202 LWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDG 261
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L + IGD E L L +P+ +GKLT+L
Sbjct: 262 IGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDR 321
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N L+ +P E+ L L+L +N++ LP + T L ++ NRL+ P ++
Sbjct: 322 NHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSLPFALTHL- 380
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L NQ ++++ E +T +
Sbjct: 381 NLKALWLAENQAQPMLRFQTEDDARTGE 408
Score = 71.3 bits (167), Expect = 5e-12
Identities = 61/249 (24%), Positives = 93/249 (37%), Gaps = 3/249 (1%)
Query: 31 NGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGN 90
+G ++ +P + HL L+ + P + P +
Sbjct: 113 SGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSF 172
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L L L+L N L VL +G L L W +R L +P E+G L +L N L
Sbjct: 173 LVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRL 232
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 210
+ +P E+ L L L L N + LPD + ++ L + NRL + +I C+ L
Sbjct: 233 EELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLS 292
Query: 211 FLQLNSNQEHALIKYTDEAT--TQTSDSNGSLASAMPSTSRVYGAQALALNATALRLPAA 268
L L N AL + + T T + L + P L+L L +
Sbjct: 293 ELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAV-LP 351
Query: 269 PEHQHPDPL 277
PE H L
Sbjct: 352 PELAHTTEL 360
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/138 (30%), Positives = 61/138 (44%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P L NL L LS N + L PE+ + +L +R + EIP+ I L+
Sbjct: 52 PKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIAD 111
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN L +P+ T L L L L + ++ LP + + LV LR N L+ P+S+
Sbjct: 112 FSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLS 171
Query: 205 KCKELMFLQLNSNQEHAL 222
+L L L N L
Sbjct: 172 FLVKLEQLDLGGNDLEVL 189
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/96 (28%), Positives = 45/96 (46%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+E+PK +L L G NE++ +P E+ + +L L + N I +P+++ AL
Sbjct: 48 LRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKAL 107
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ N L + P + + L L LN AL
Sbjct: 108 EIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQAL 143
>AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein.
Length = 1601
Score = 81.0 bits (191), Expect = 6e-15
Identities = 60/216 (27%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Query: 8 IRENHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+REN + +L + K +L L G ++ +P L + L+L +N++S P E
Sbjct: 129 LRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELG 188
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P E+G L L +L LS N L L IG L++L ++
Sbjct: 189 NLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNR 248
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+ + IG L N L +P + L KL L ++ N +E LP + AL
Sbjct: 249 LCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVAL 308
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+LR+NRL P + EL L + N+ +L
Sbjct: 309 SVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSL 344
Score = 75.4 bits (177), Expect = 3e-13
Identities = 52/191 (27%), Positives = 81/191 (42%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ +I EIP + C +E N +S P P +
Sbjct: 58 LDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGD 117
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+GNL NLV L L N L L + L KLE L+ +P +G L L
Sbjct: 118 VGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDR 177
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P E+ +L +L L + N++E LP + + L L N L + P I + K
Sbjct: 178 NQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLK 237
Query: 208 ELMFLQLNSNQ 218
+L L+++ N+
Sbjct: 238 QLSILKVDQNR 248
Score = 73.3 bits (172), Expect = 1e-12
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +++ +P L + L + +N++ P E P
Sbjct: 173 LWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDG 232
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L + IGD E L L +P+ +GKLT+L
Sbjct: 233 IGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDR 292
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N L+ +P E+ L L+L +N++ LP + T L ++ NRL+ P ++
Sbjct: 293 NHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSLPFALTHL- 351
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L NQ ++++ E +T +
Sbjct: 352 NLKALWLAENQAQPMLRFQTEDDARTGE 379
Score = 71.3 bits (167), Expect = 5e-12
Identities = 61/249 (24%), Positives = 93/249 (37%), Gaps = 3/249 (1%)
Query: 31 NGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGN 90
+G ++ +P + HL L+ + P + P +
Sbjct: 84 SGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSF 143
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L L L+L N L VL +G L L W +R L +P E+G L +L N L
Sbjct: 144 LVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRL 203
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 210
+ +P E+ L L L L N + LPD + ++ L + NRL + +I C+ L
Sbjct: 204 EELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLS 263
Query: 211 FLQLNSNQEHALIKYTDEAT--TQTSDSNGSLASAMPSTSRVYGAQALALNATALRLPAA 268
L L N AL + + T T + L + P L+L L +
Sbjct: 264 ELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAV-LP 322
Query: 269 PEHQHPDPL 277
PE H L
Sbjct: 323 PELAHTTEL 331
Score = 62.1 bits (144), Expect = 3e-09
Identities = 41/132 (31%), Positives = 60/132 (45%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L NL L LS N + L PE+ + +L +R + EIP+ I L+ GN L
Sbjct: 29 LLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPL 88
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 210
+P+ T L L L L + ++ LP + + LV LR N L+ P+S+ +L
Sbjct: 89 SRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLE 148
Query: 211 FLQLNSNQEHAL 222
L L N L
Sbjct: 149 QLDLGGNDLEVL 160
Score = 40.7 bits (91), Expect = 0.008
Identities = 23/87 (26%), Positives = 39/87 (44%)
Query: 136 KLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
+L L G NE++ +P E+ + +L L + N I +P+++ AL + N
Sbjct: 28 RLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNP 87
Query: 196 LEQFPSSILKCKELMFLQLNSNQEHAL 222
L + P + + L L LN AL
Sbjct: 88 LSRLPDGFTQLRSLAHLALNDVSLQAL 114
>AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein.
Length = 1630
Score = 81.0 bits (191), Expect = 6e-15
Identities = 60/216 (27%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Query: 8 IRENHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
+REN + +L + K +L L G ++ +P L + L+L +N++S P E
Sbjct: 158 LRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELG 217
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG 126
P E+G L L +L LS N L L IG L++L ++
Sbjct: 218 NLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNR 277
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+ + IG L N L +P + L KL L ++ N +E LP + AL
Sbjct: 278 LCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVAL 337
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+LR+NRL P + EL L + N+ +L
Sbjct: 338 SVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSL 373
Score = 77.8 bits (183), Expect = 6e-14
Identities = 53/197 (26%), Positives = 83/197 (42%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
++ L L+ ++ E+P + L + L L N+I P E
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL+ L L L N + L+ +P ++G L L
Sbjct: 95 PEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLV 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
T R N LK++P ++ L KL L L N +E LPDT+ + L L N+L P
Sbjct: 155 TLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPP 214
Query: 202 SILKCKELMFLQLNSNQ 218
+ + L+ L ++ N+
Sbjct: 215 ELGNLRRLVCLDVSENR 231
Score = 75.4 bits (177), Expect = 3e-13
Identities = 52/191 (27%), Positives = 81/191 (42%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ +I EIP + C +E N +S P P +
Sbjct: 87 LDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGD 146
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+GNL NLV L L N L L + L KLE L+ +P +G L L
Sbjct: 147 VGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDR 206
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L +P E+ +L +L L + N++E LP + + L L N L + P I + K
Sbjct: 207 NQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLK 266
Query: 208 ELMFLQLNSNQ 218
+L L+++ N+
Sbjct: 267 QLSILKVDQNR 277
Score = 73.3 bits (172), Expect = 1e-12
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 1/208 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +++ +P L + L + +N++ P E P
Sbjct: 202 LWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDG 261
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IG LK L L + N L + IGD E L L +P+ +GKLT+L
Sbjct: 262 IGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDR 321
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N L+ +P E+ L L+L +N++ LP + T L ++ NRL+ P ++
Sbjct: 322 NHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSLPFALTHL- 380
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSD 235
L L L NQ ++++ E +T +
Sbjct: 381 NLKALWLAENQAQPMLRFQTEDDARTGE 408
Score = 71.3 bits (167), Expect = 5e-12
Identities = 61/249 (24%), Positives = 93/249 (37%), Gaps = 3/249 (1%)
Query: 31 NGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGN 90
+G ++ +P + HL L+ + P + P +
Sbjct: 113 SGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSF 172
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L L L+L N L VL +G L L W +R L +P E+G L +L N L
Sbjct: 173 LVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRL 232
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 210
+ +P E+ L L L L N + LPD + ++ L + NRL + +I C+ L
Sbjct: 233 EELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLS 292
Query: 211 FLQLNSNQEHALIKYTDEAT--TQTSDSNGSLASAMPSTSRVYGAQALALNATALRLPAA 268
L L N AL + + T T + L + P L+L L +
Sbjct: 293 ELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAV-LP 351
Query: 269 PEHQHPDPL 277
PE H L
Sbjct: 352 PELAHTTEL 360
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/138 (30%), Positives = 61/138 (44%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P L NL L LS N + L PE+ + +L +R + EIP+ I L+
Sbjct: 52 PKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIAD 111
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN L +P+ T L L L L + ++ LP + + LV LR N L+ P+S+
Sbjct: 112 FSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLS 171
Query: 205 KCKELMFLQLNSNQEHAL 222
+L L L N L
Sbjct: 172 FLVKLEQLDLGGNDLEVL 189
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/96 (28%), Positives = 45/96 (46%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+E+PK +L L G NE++ +P E+ + +L L + N I +P+++ AL
Sbjct: 48 LRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKAL 107
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ N L + P + + L L LN AL
Sbjct: 108 EIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQAL 143
>BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein.
Length = 748
Score = 77.8 bits (183), Expect = 6e-14
Identities = 56/212 (26%), Positives = 96/212 (45%), Gaps = 4/212 (1%)
Query: 8 IRENHILALIEQAIAKKKSR--LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
++ H + +++A+ + S LSL+G ++ + PG Y + L +N+ + P +
Sbjct: 71 LQPQHTVRSLDRALEEAGSSGILSLSGRKLRDFPGSGYDLTDTTQADLSRNRFTEIPSDV 130
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P I NL+ L LN+S N L+ L + DL L+ +
Sbjct: 131 WLFAPLETLNLYHNCIKTIPEAIKNLQMLTYLNISRNLLSTLPKYLFDLP-LKVLVVSNN 189
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L IP+EIGKL L NE++ +P++M L LR L + N + LPD + +
Sbjct: 190 KLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHVLPDELGDL-P 248
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
LV + N++ + P K L + L++N
Sbjct: 249 LVKLDFSCNKVTEIPVCYRKLHHLQVIILDNN 280
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/180 (21%), Positives = 78/180 (43%), Gaps = 2/180 (1%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + +LS N + ++ LE +K IP+ I L L N
Sbjct: 109 DLTDTTQADLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTIPEAIKNLQMLTYLNISRNL 168
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L T+P+ + L L+ L + NN++ ++P+ + ++ L+ ++ N ++ P + K L
Sbjct: 169 LSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSL 227
Query: 210 MFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQALALNATALRLPAA 268
L + N H L + D + + + +P R ++ Q + L+ L++P A
Sbjct: 228 RELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPA 287
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 77.8 bits (183), Expect = 6e-14
Identities = 43/134 (32%), Positives = 70/134 (52%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L+NL LN+S+N L +L EI +L L+ + L I + +L+ L+
Sbjct: 121 PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD 180
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L T+P +SL+ L L L +N++++LP ++RM L H + +N LE P +
Sbjct: 181 LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA 240
Query: 205 KCKELMFLQLNSNQ 218
+ L L L N+
Sbjct: 241 GMESLELLYLRRNK 254
Score = 72.1 bits (169), Expect = 3e-12
Identities = 55/197 (27%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+K +L+L+G ++E+P ++ + V+ +S E
Sbjct: 35 ARKSGQLNLSGRNLSEVPQCVWR-INVDIPEEANQNLSFGATERWWEQTDLTKLIISNNK 93
Query: 82 XXXPTE-IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQL 140
T+ + L L L++ N L L I +LE L+ + LK +P+EI L L
Sbjct: 94 LQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNL 153
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
+ NEL I E L+ L L L NN + T+P + +++LV NL +N L+ P
Sbjct: 154 KCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLP 213
Query: 201 SSILKCKELMFLQLNSN 217
+ I + K L L NSN
Sbjct: 214 AEINRMKRLKHLDCNSN 230
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 1/168 (0%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPE 110
L +H N+++ P P EI NL+NL L L +N L +
Sbjct: 110 LDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEG 169
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
L LE + L +P L+ L NELK++P E+ + +L+ L +
Sbjct: 170 FEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNS 229
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
N +ET+P + M +L LR N+L P C L L + NQ
Sbjct: 230 NLLETIPPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQ 276
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 93 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 152
+L L +S N L L ++ L L + L +P I +L L N+LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI 142
Query: 153 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 212
+PEE+T+L L+ L L++N++ + + ++++ L +L NN L P+S L+ L
Sbjct: 143 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL 202
Query: 213 QLNSNQEHAL-IKYTDEATTQTSDSNGSLASAM-PSTSRVYGAQALALNATALR-LPAAP 269
L+SN+ +L + + D N +L + P + + + L L LR LP P
Sbjct: 203 NLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFP 262
Score = 64.5 bits (150), Expect = 6e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 85 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 441 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 500
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 202
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 501 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 560
Query: 203 ILKCKELMFLQLNSN 217
+ C L L L+ N
Sbjct: 561 LGNCVNLRTLLLDGN 575
Score = 60.5 bits (140), Expect = 9e-09
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 3/171 (1%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 107
+E L L N ++ P P EI +K L +L+ + N L +
Sbjct: 176 LEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETI 235
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWL 166
PE+ +E LE + R L+ +P E + L N+++ + E + L + L
Sbjct: 236 PPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 294
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L +N+++++PD + + +L +L NN + P S L L FL L N
Sbjct: 295 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS-LGNLHLKFLALEGN 344
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 6/147 (4%)
Query: 127 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 437 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 496
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL----IKYTDEATTQTSDSNGSLA 241
L NL NR + P + + L + +++NQ ++ +K + TT +N L
Sbjct: 497 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNN-DLL 555
Query: 242 SAMPSTSRVYGAQALALNATALRLPAA 268
P + L L+ R+P A
Sbjct: 556 QIPPELGNCVNLRTLLLDGNPFRVPRA 582
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
T L N+L+++ +++ L L L + +NQ+ +LP + + L N+ +N+L+
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK 141
Query: 198 QFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSD---SNGSLASAMPSTSRVYGAQ 254
P I + L L L N E I E + D SN L + S S +
Sbjct: 142 ILPEEITNLRNLKCLYLQHN-ELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLV 200
Query: 255 ALALNATALR-LPA 267
L L++ L+ LPA
Sbjct: 201 RLNLSSNELKSLPA 214
Score = 37.9 bits (84), Expect = 0.057
Identities = 34/137 (24%), Positives = 52/137 (37%), Gaps = 1/137 (0%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ L N + IP L +E LYL +NK+ P
Sbjct: 220 KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEM 279
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ +L +++ L+L N L + EI L LE + + +P +G L L
Sbjct: 280 LEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKF 338
Query: 143 FGARGNELKTIPEEMTS 159
GN L+TI E+ S
Sbjct: 339 LALEGNPLRTIRREIIS 355
Score = 33.5 bits (73), Expect = 1.2
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 8 IRENHILAL---IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SVFPV 63
+R N + +L +E + + LS N F++ +P +LY +E + + N++ SV P
Sbjct: 479 LRNNFLNSLPEEMESLVRLQTINLSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQ 536
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNV 106
+ P E+GN NL L L NP V
Sbjct: 537 KMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRV 579
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 77.8 bits (183), Expect = 6e-14
Identities = 43/134 (32%), Positives = 70/134 (52%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L+NL LN+S+N L +L EI +L L+ + L I + +L+ L+
Sbjct: 100 PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD 159
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L T+P +SL+ L L L +N++++LP ++RM L H + +N LE P +
Sbjct: 160 LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA 219
Query: 205 KCKELMFLQLNSNQ 218
+ L L L N+
Sbjct: 220 GMESLELLYLRRNK 233
Score = 72.1 bits (169), Expect = 3e-12
Identities = 55/197 (27%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+K +L+L+G ++E+P ++ + V+ +S E
Sbjct: 14 ARKSGQLNLSGRNLSEVPQCVWR-INVDIPEEANQNLSFGATERWWEQTDLTKLIISNNK 72
Query: 82 XXXPTE-IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQL 140
T+ + L L L++ N L L I +LE L+ + LK +P+EI L L
Sbjct: 73 LQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNL 132
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
+ NEL I E L+ L L L NN + T+P + +++LV NL +N L+ P
Sbjct: 133 KCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLP 192
Query: 201 SSILKCKELMFLQLNSN 217
+ I + K L L NSN
Sbjct: 193 AEINRMKRLKHLDCNSN 209
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 1/168 (0%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPE 110
L +H N+++ P P EI NL+NL L L +N L +
Sbjct: 89 LDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEG 148
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
L LE + L +P L+ L NELK++P E+ + +L+ L +
Sbjct: 149 FEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNS 208
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
N +ET+P + M +L LR N+L P C L L + NQ
Sbjct: 209 NLLETIPPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQ 255
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 93 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 152
+L L +S N L L ++ L L + L +P I +L L N+LK
Sbjct: 62 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI 121
Query: 153 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 212
+PEE+T+L L+ L L++N++ + + ++++ L +L NN L P+S L+ L
Sbjct: 122 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL 181
Query: 213 QLNSNQEHAL-IKYTDEATTQTSDSNGSLASAM-PSTSRVYGAQALALNATALR-LPAAP 269
L+SN+ +L + + D N +L + P + + + L L LR LP P
Sbjct: 182 NLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFP 241
Score = 64.5 bits (150), Expect = 6e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 85 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 420 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 479
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 202
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 480 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 539
Query: 203 ILKCKELMFLQLNSN 217
+ C L L L+ N
Sbjct: 540 LGNCVNLRTLLLDGN 554
Score = 60.5 bits (140), Expect = 9e-09
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 3/171 (1%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 107
+E L L N ++ P P EI +K L +L+ + N L +
Sbjct: 155 LEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETI 214
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWL 166
PE+ +E LE + R L+ +P E + L N+++ + E + L + L
Sbjct: 215 PPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 273
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L +N+++++PD + + +L +L NN + P S L L FL L N
Sbjct: 274 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS-LGNLHLKFLALEGN 323
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 6/147 (4%)
Query: 127 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 416 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 475
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL----IKYTDEATTQTSDSNGSLA 241
L NL NR + P + + L + +++NQ ++ +K + TT +N L
Sbjct: 476 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNN-DLL 534
Query: 242 SAMPSTSRVYGAQALALNATALRLPAA 268
P + L L+ R+P A
Sbjct: 535 QIPPELGNCVNLRTLLLDGNPFRVPRA 561
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
T L N+L+++ +++ L L L + +NQ+ +LP + + L N+ +N+L+
Sbjct: 61 TDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK 120
Query: 198 QFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSD---SNGSLASAMPSTSRVYGAQ 254
P I + L L L N E I E + D SN L + S S +
Sbjct: 121 ILPEEITNLRNLKCLYLQHN-ELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLV 179
Query: 255 ALALNATALR-LPA 267
L L++ L+ LPA
Sbjct: 180 RLNLSSNELKSLPA 193
Score = 37.9 bits (84), Expect = 0.057
Identities = 34/137 (24%), Positives = 52/137 (37%), Gaps = 1/137 (0%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ L N + IP L +E LYL +NK+ P
Sbjct: 199 KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEM 258
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ +L +++ L+L N L + EI L LE + + +P +G L L
Sbjct: 259 LEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKF 317
Query: 143 FGARGNELKTIPEEMTS 159
GN L+TI E+ S
Sbjct: 318 LALEGNPLRTIRREIIS 334
Score = 33.5 bits (73), Expect = 1.2
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 8 IRENHILAL---IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SVFPV 63
+R N + +L +E + + LS N F++ +P +LY +E + + N++ SV P
Sbjct: 458 LRNNFLNSLPEEMESLVRLQTINLSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQ 515
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNV 106
+ P E+GN NL L L NP V
Sbjct: 516 KMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRV 558
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 77.8 bits (183), Expect = 6e-14
Identities = 43/134 (32%), Positives = 70/134 (52%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L+NL LN+S+N L +L EI +L L+ + L I + +L+ L+
Sbjct: 121 PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD 180
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L T+P +SL+ L L L +N++++LP ++RM L H + +N LE P +
Sbjct: 181 LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA 240
Query: 205 KCKELMFLQLNSNQ 218
+ L L L N+
Sbjct: 241 GMESLELLYLRRNK 254
Score = 72.1 bits (169), Expect = 3e-12
Identities = 55/197 (27%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+K +L+L+G ++E+P ++ + V+ +S E
Sbjct: 35 ARKSGQLNLSGRNLSEVPQCVWR-INVDIPEEANQNLSFGATERWWEQTDLTKLIISNNK 93
Query: 82 XXXPTE-IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQL 140
T+ + L L L++ N L L I +LE L+ + LK +P+EI L L
Sbjct: 94 LQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNL 153
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
+ NEL I E L+ L L L NN + T+P + +++LV NL +N L+ P
Sbjct: 154 KCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLP 213
Query: 201 SSILKCKELMFLQLNSN 217
+ I + K L L NSN
Sbjct: 214 AEINRMKRLKHLDCNSN 230
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 1/168 (0%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPE 110
L +H N+++ P P EI NL+NL L L +N L +
Sbjct: 110 LDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEG 169
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
L LE + L +P L+ L NELK++P E+ + +L+ L +
Sbjct: 170 FEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNS 229
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
N +ET+P + M +L LR N+L P C L L + NQ
Sbjct: 230 NLLETIPPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQ 276
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 93 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 152
+L L +S N L L ++ L L + L +P I +L L N+LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI 142
Query: 153 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 212
+PEE+T+L L+ L L++N++ + + ++++ L +L NN L P+S L+ L
Sbjct: 143 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL 202
Query: 213 QLNSNQEHAL-IKYTDEATTQTSDSNGSLASAM-PSTSRVYGAQALALNATALR-LPAAP 269
L+SN+ +L + + D N +L + P + + + L L LR LP P
Sbjct: 203 NLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFP 262
Score = 64.5 bits (150), Expect = 6e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 85 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 441 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 500
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 202
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 501 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 560
Query: 203 ILKCKELMFLQLNSN 217
+ C L L L+ N
Sbjct: 561 LGNCVNLRTLLLDGN 575
Score = 60.5 bits (140), Expect = 9e-09
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 3/171 (1%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 107
+E L L N ++ P P EI +K L +L+ + N L +
Sbjct: 176 LEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETI 235
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWL 166
PE+ +E LE + R L+ +P E + L N+++ + E + L + L
Sbjct: 236 PPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 294
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L +N+++++PD + + +L +L NN + P S L L FL L N
Sbjct: 295 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS-LGNLHLKFLALEGN 344
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 6/147 (4%)
Query: 127 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 437 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 496
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL----IKYTDEATTQTSDSNGSLA 241
L NL NR + P + + L + +++NQ ++ +K + TT +N L
Sbjct: 497 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNN-DLL 555
Query: 242 SAMPSTSRVYGAQALALNATALRLPAA 268
P + L L+ R+P A
Sbjct: 556 QIPPELGNCVNLRTLLLDGNPFRVPRA 582
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
T L N+L+++ +++ L L L + +NQ+ +LP + + L N+ +N+L+
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK 141
Query: 198 QFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSD---SNGSLASAMPSTSRVYGAQ 254
P I + L L L N E I E + D SN L + S S +
Sbjct: 142 ILPEEITNLRNLKCLYLQHN-ELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLV 200
Query: 255 ALALNATALR-LPA 267
L L++ L+ LPA
Sbjct: 201 RLNLSSNELKSLPA 214
Score = 37.9 bits (84), Expect = 0.057
Identities = 34/137 (24%), Positives = 52/137 (37%), Gaps = 1/137 (0%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ L N + IP L +E LYL +NK+ P
Sbjct: 220 KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEM 279
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ +L +++ L+L N L + EI L LE + + +P +G L L
Sbjct: 280 LEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKF 338
Query: 143 FGARGNELKTIPEEMTS 159
GN L+TI E+ S
Sbjct: 339 LALEGNPLRTIRREIIS 355
Score = 33.5 bits (73), Expect = 1.2
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 8 IRENHILAL---IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SVFPV 63
+R N + +L +E + + LS N F++ +P +LY +E + + N++ SV P
Sbjct: 479 LRNNFLNSLPEEMESLVRLQTINLSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQ 536
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNV 106
+ P E+GN NL L L NP V
Sbjct: 537 KMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRV 579
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 185 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 244
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 245 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 304
Query: 205 KCKELMFLQLNSNQE-HAL 222
+ L L LN N H+L
Sbjct: 305 TLENLEELYLNDNPNLHSL 323
Score = 72.5 bits (170), Expect = 2e-12
Identities = 61/216 (28%), Positives = 87/216 (40%), Gaps = 6/216 (2%)
Query: 8 IRENHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXX 66
IREN I L E SRL L ++ IP L C +E L L N IS P E
Sbjct: 58 IRENKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESL 116
Query: 67 XXXXXXXXXXXXXXXXXXPTEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWC 122
+G + +LN+ +N +N + I K L
Sbjct: 117 LSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNM 176
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
L +P + G T + N+L IPE+++ L L L L NN ++ LP +
Sbjct: 177 KDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGN 236
Query: 183 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
+ L +L N+LE P+ I K+L L L +NQ
Sbjct: 237 LRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQ 272
Score = 67.3 bits (157), Expect = 8e-11
Identities = 37/117 (31%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ + L +L L L +N + + +I +L KL +K++P EIG L+ L G
Sbjct: 21 PSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGNLSSLSRLG 80
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRLEQFP 200
R N L IP + + L L LENN I TLP++ + + L L N + +P
Sbjct: 81 LRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYP 137
Score = 66.9 bits (156), Expect = 1e-10
Identities = 35/107 (32%), Positives = 58/107 (54%)
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
+ +L+KL L+EIP + +L L T R N + T+ +++ +L+KL L++
Sbjct: 1 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 60
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+I+ LP + +++L LR NRL P S+ KC L L L +N
Sbjct: 61 NKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENN 107
Score = 64.1 bits (149), Expect = 8e-10
Identities = 34/117 (29%), Positives = 61/117 (52%)
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+ NLK L L+L +N L + + L+ L + + + K+I L++L R
Sbjct: 1 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 60
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N++K +P E+ +L+ L L L N++ +P ++ + +AL NL NN + P S+L
Sbjct: 61 NKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 117
Score = 61.7 bits (143), Expect = 4e-09
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 26/199 (13%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
KK L L ++ EIP ++Y + LYL N+I+ +
Sbjct: 5 KKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIK 64
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P EIGNL +L L L YN L+ IP+ + K + L+
Sbjct: 65 QLPAEIGNLSSLSRLGLRYNRLSA-----------------------IPRSLAKCSALEE 101
Query: 143 FGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFP 200
N + T+PE ++SL KL LTL N + P + + + N+ +NR+ + P
Sbjct: 102 LNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIP 161
Query: 201 SSIL-KCKELMFLQLNSNQ 218
I + K L L + NQ
Sbjct: 162 FGIFSRAKVLSKLNMKDNQ 180
Score = 58.8 bits (136), Expect = 3e-08
Identities = 45/191 (23%), Positives = 76/191 (39%), Gaps = 2/191 (1%)
Query: 28 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 150 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 209
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 210 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 269
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 205
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 270 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 329
Query: 206 CKELMFLQLNS 216
C +L + + +
Sbjct: 330 CSKLSIMSIEN 340
Score = 40.3 bits (90), Expect = 0.011
Identities = 25/89 (28%), Positives = 43/89 (48%)
Query: 134 IGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRN 193
+ L +L R N+L+ IP + L L L L N+I T+ + ++ L ++R
Sbjct: 1 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 60
Query: 194 NRLEQFPSSILKCKELMFLQLNSNQEHAL 222
N+++Q P+ I L L L N+ A+
Sbjct: 61 NKIKQLPAEIGNLSSLSRLGLRYNRLSAI 89
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 77.8 bits (183), Expect = 6e-14
Identities = 43/134 (32%), Positives = 70/134 (52%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+ I L+NL LN+S+N L +L EI +L L+ + L I + +L+ L+
Sbjct: 121 PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD 180
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L T+P +SL+ L L L +N++++LP ++RM L H + +N LE P +
Sbjct: 181 LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA 240
Query: 205 KCKELMFLQLNSNQ 218
+ L L L N+
Sbjct: 241 GMESLELLYLRRNK 254
Score = 72.1 bits (169), Expect = 3e-12
Identities = 55/197 (27%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+K +L+L+G ++E+P ++ + V+ +S E
Sbjct: 35 ARKSGQLNLSGRNLSEVPQCVWR-INVDIPEEANQNLSFGATERWWEQTDLTKLIISNNK 93
Query: 82 XXXPTE-IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQL 140
T+ + L L L++ N L L I +LE L+ + LK +P+EI L L
Sbjct: 94 LQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNL 153
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
+ NEL I E L+ L L L NN + T+P + +++LV NL +N L+ P
Sbjct: 154 KCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLP 213
Query: 201 SSILKCKELMFLQLNSN 217
+ I + K L L NSN
Sbjct: 214 AEINRMKRLKHLDCNSN 230
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 1/168 (0%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPE 110
L +H N+++ P P EI NL+NL L L +N L +
Sbjct: 110 LDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEG 169
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
L LE + L +P L+ L NELK++P E+ + +L+ L +
Sbjct: 170 FEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNS 229
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
N +ET+P + M +L LR N+L P C L L + NQ
Sbjct: 230 NLLETIPPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQ 276
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 93 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 152
+L L +S N L L ++ L L + L +P I +L L N+LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI 142
Query: 153 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 212
+PEE+T+L L+ L L++N++ + + ++++ L +L NN L P+S L+ L
Sbjct: 143 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL 202
Query: 213 QLNSNQEHAL-IKYTDEATTQTSDSNGSLASAM-PSTSRVYGAQALALNATALR-LPAAP 269
L+SN+ +L + + D N +L + P + + + L L LR LP P
Sbjct: 203 NLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFP 262
Score = 64.5 bits (150), Expect = 6e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 85 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 441 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 500
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 202
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 501 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 560
Query: 203 ILKCKELMFLQLNSN 217
+ C L L L+ N
Sbjct: 561 LGNCVNLRTLLLDGN 575
Score = 60.5 bits (140), Expect = 9e-09
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 3/171 (1%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 107
+E L L N ++ P P EI +K L +L+ + N L +
Sbjct: 176 LEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETI 235
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWL 166
PE+ +E LE + R L+ +P E + L N+++ + E + L + L
Sbjct: 236 PPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 294
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L +N+++++PD + + +L +L NN + P S L L FL L N
Sbjct: 295 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS-LGNLHLKFLALEGN 344
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 6/147 (4%)
Query: 127 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 437 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 496
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL----IKYTDEATTQTSDSNGSLA 241
L NL NR + P + + L + +++NQ ++ +K + TT +N L
Sbjct: 497 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNN-DLL 555
Query: 242 SAMPSTSRVYGAQALALNATALRLPAA 268
P + L L+ R+P A
Sbjct: 556 QIPPELGNCVNLRTLLLDGNPFRVPRA 582
Score = 43.6 bits (98), Expect = 0.001
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
T L N+L+++ +++ L L L + +NQ+ +LP + + L N+ +N+L+
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK 141
Query: 198 QFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSD---SNGSLASAMPSTSRVYGAQ 254
P I + L L L N E I E + D SN L + S S +
Sbjct: 142 ILPEEITNLRNLKCLYLQHN-ELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLV 200
Query: 255 ALALNATALR-LPA 267
L L++ L+ LPA
Sbjct: 201 RLNLSSNELKSLPA 214
Score = 37.9 bits (84), Expect = 0.057
Identities = 34/137 (24%), Positives = 52/137 (37%), Gaps = 1/137 (0%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ L N + IP L +E LYL +NK+ P
Sbjct: 220 KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEM 279
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ +L +++ L+L N L + EI L LE + + +P +G L L
Sbjct: 280 LEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKF 338
Query: 143 FGARGNELKTIPEEMTS 159
GN L+TI E+ S
Sbjct: 339 LALEGNPLRTIRREIIS 355
Score = 33.5 bits (73), Expect = 1.2
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 8 IRENHILAL---IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SVFPV 63
+R N + +L +E + + LS N F++ +P +LY +E + + N++ SV P
Sbjct: 479 LRNNFLNSLPEEMESLVRLQTINLSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQ 536
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNV 106
+ P E+GN NL L L NP V
Sbjct: 537 KMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRV 579
>BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat
containing 28 protein.
Length = 367
Score = 77.4 bits (182), Expect = 8e-14
Identities = 50/185 (27%), Positives = 88/185 (47%), Gaps = 5/185 (2%)
Query: 34 EITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX-XXXXXXXXXXXXXXXPTEIGNLK 92
E+ + GL Y +E LY+ +N ++ P P IG+L
Sbjct: 33 ELLKDEGLQY----LERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLV 88
Query: 93 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 152
L L+LS N L ++ PEIG L L L+ +P E+G L +L T N L T
Sbjct: 89 KLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLT 148
Query: 153 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 212
+PE + L++LT++ N++ +P + ++ +L ++ NRL P + + +EL ++
Sbjct: 149 LPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYV 208
Query: 213 QLNSN 217
+++N
Sbjct: 209 YVDNN 213
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 3/122 (2%)
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG-KLTQLDTFGARGNELKTIPEE 156
NL + PL +L E L+ LE + R L +P+ + KL L N + +PE
Sbjct: 26 NLHHFPLELLKDE--GLQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEA 83
Query: 157 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
+ SL KL+ L L +N +E + + R+ AL H L NN+L+ P + KEL L +++
Sbjct: 84 IGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDIST 143
Query: 217 NQ 218
N+
Sbjct: 144 NR 145
Score = 59.7 bits (138), Expect = 2e-08
Identities = 40/129 (31%), Positives = 66/129 (51%), Gaps = 2/129 (1%)
Query: 91 LKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
L NLV L L N + V++PE IG L KL+ + L+ + EIG+L L N+
Sbjct: 64 LPNLVELYLHSNNI-VVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQ 122
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L+ +P E+ L +L+ L + N++ TLP+ + +L + + NRL P + + L
Sbjct: 123 LQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSL 182
Query: 210 MFLQLNSNQ 218
L + N+
Sbjct: 183 NELSMAGNR 191
>AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein.
Length = 312
Score = 77.4 bits (182), Expect = 8e-14
Identities = 50/185 (27%), Positives = 88/185 (47%), Gaps = 5/185 (2%)
Query: 34 EITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX-XXXXXXXXXXXXXXXPTEIGNLK 92
E+ + GL Y +E LY+ +N ++ P P IG+L
Sbjct: 33 ELLKDEGLQY----LERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLV 88
Query: 93 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 152
L L+LS N L ++ PEIG L L L+ +P E+G L +L T N L T
Sbjct: 89 KLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLT 148
Query: 153 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 212
+PE + L++LT++ N++ +P + ++ +L ++ NRL P + + +EL ++
Sbjct: 149 LPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYV 208
Query: 213 QLNSN 217
+++N
Sbjct: 209 YVDNN 213
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 3/122 (2%)
Query: 98 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG-KLTQLDTFGARGNELKTIPEE 156
NL + PL +L E L+ LE + R L +P+ + KL L N + +PE
Sbjct: 26 NLHHFPLELLKDE--GLQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEA 83
Query: 157 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
+ SL KL+ L L +N +E + + R+ AL H L NN+L+ P + KEL L +++
Sbjct: 84 IGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDIST 143
Query: 217 NQ 218
N+
Sbjct: 144 NR 145
Score = 59.7 bits (138), Expect = 2e-08
Identities = 40/129 (31%), Positives = 66/129 (51%), Gaps = 2/129 (1%)
Query: 91 LKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
L NLV L L N + V++PE IG L KL+ + L+ + EIG+L L N+
Sbjct: 64 LPNLVELYLHSNNI-VVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQ 122
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L+ +P E+ L +L+ L + N++ TLP+ + +L + + NRL P + + L
Sbjct: 123 LQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSL 182
Query: 210 MFLQLNSNQ 218
L + N+
Sbjct: 183 NELSMAGNR 191
>BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats and
death domain containing protein.
Length = 893
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/133 (31%), Positives = 71/133 (53%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L +L +L+LS+N L L + + L A + L E+P+ +G L L
Sbjct: 118 PAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLT 177
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+T+P + +L+ L+ L L N ++TLP + + +L+ NL +NRL+ P+S+
Sbjct: 178 VTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLA 237
Query: 205 KCKELMFLQLNSN 217
+ L L L+SN
Sbjct: 238 GLRSLRLLVLHSN 250
Score = 55.6 bits (128), Expect = 3e-07
Identities = 38/134 (28%), Positives = 63/134 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + ++ L L LS+N L+ L +G L L L+ +P +G L+ L
Sbjct: 141 PACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLD 200
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L T+P E+ L L L L +N++++LP ++ + +L L +N L P+ +
Sbjct: 201 LSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLA 260
Query: 205 KCKELMFLQLNSNQ 218
+ L L L NQ
Sbjct: 261 RLPLLTRLDLRDNQ 274
Score = 47.2 bits (107), Expect = 9e-05
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 4/145 (2%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
++E+P L + L + N++ P P EIG L +L
Sbjct: 160 LSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSL 219
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ LNL+ N L L + L L + L +P ++ +L L R N+L+ +P
Sbjct: 220 LELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLP 279
Query: 155 EEMTSLAKLRWLTLENNQI-ETLPD 178
E+ +R L+ N + E PD
Sbjct: 280 PELLDAPFVR---LQGNPLGEASPD 301
Score = 45.6 bits (103), Expect = 3e-04
Identities = 27/96 (28%), Positives = 49/96 (51%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+ +P + ++ L N L +PE + +L L +LT+ +N+++TLP + ++ L
Sbjct: 137 LETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTL 196
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+L N L+ P I L+ L L SN+ +L
Sbjct: 197 QRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSL 232
Score = 44.0 bits (99), Expect = 9e-04
Identities = 26/96 (27%), Positives = 43/96 (44%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMD 181
C R L +P + L L N L+T+P + + L L L +N + LP+ +
Sbjct: 109 CLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALG 168
Query: 182 RMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+ AL + +NRL+ P ++ L L L+ N
Sbjct: 169 ALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQN 204
>AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein.
Length = 910
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/133 (31%), Positives = 71/133 (53%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L +L +L+LS+N L L + + L A + L E+P+ +G L L
Sbjct: 118 PAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLT 177
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+T+P + +L+ L+ L L N ++TLP + + +L+ NL +NRL+ P+S+
Sbjct: 178 VTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLA 237
Query: 205 KCKELMFLQLNSN 217
+ L L L+SN
Sbjct: 238 GLRSLRLLVLHSN 250
Score = 55.6 bits (128), Expect = 3e-07
Identities = 38/134 (28%), Positives = 63/134 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + ++ L L LS+N L+ L +G L L L+ +P +G L+ L
Sbjct: 141 PACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLD 200
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L T+P E+ L L L L +N++++LP ++ + +L L +N L P+ +
Sbjct: 201 LSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLA 260
Query: 205 KCKELMFLQLNSNQ 218
+ L L L NQ
Sbjct: 261 RLPLLTRLDLRDNQ 274
Score = 47.2 bits (107), Expect = 9e-05
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 4/145 (2%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
++E+P L + L + N++ P P EIG L +L
Sbjct: 160 LSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSL 219
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ LNL+ N L L + L L + L +P ++ +L L R N+L+ +P
Sbjct: 220 LELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLP 279
Query: 155 EEMTSLAKLRWLTLENNQI-ETLPD 178
E+ +R L+ N + E PD
Sbjct: 280 PELLDAPFVR---LQGNPLGEASPD 301
Score = 45.6 bits (103), Expect = 3e-04
Identities = 27/96 (28%), Positives = 49/96 (51%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+ +P + ++ L N L +PE + +L L +LT+ +N+++TLP + ++ L
Sbjct: 137 LETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTL 196
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+L N L+ P I L+ L L SN+ +L
Sbjct: 197 QRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSL 232
Score = 44.0 bits (99), Expect = 9e-04
Identities = 26/96 (27%), Positives = 43/96 (44%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMD 181
C R L +P + L L N L+T+P + + L L L +N + LP+ +
Sbjct: 109 CLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALG 168
Query: 182 RMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+ AL + +NRL+ P ++ L L L+ N
Sbjct: 169 ALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQN 204
>BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 74.5 bits (175), Expect = 5e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 655 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 714
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 715 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 205 KC 206
+C
Sbjct: 775 EC 776
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEI---PKEIGKLTQLD 141
P I +L NL ++L N L I EI + L C ++ I P +IG LT L+
Sbjct: 607 PHSIFSLHNLQEIDLKDNNLKT-IEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLE 665
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+++ IP ++ KLR+L L +N + LP + + L + + NR+E P
Sbjct: 666 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 725
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMP 245
+ +C++L L L +N +L E T T + G+ +P
Sbjct: 726 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 770
Score = 56.0 bits (129), Expect = 2e-07
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
T++G +++N L VL + ++ +L +LE C+ L+ IP I L L
Sbjct: 563 TDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCD---LERIPHSIFSLHNLQEI 619
Query: 144 GARGNELKTIPE--EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N LKTI E L +L L L N I +P + +T L L N++E+ P+
Sbjct: 620 DLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPT 679
Query: 202 SILKCKELMFLQLNSN 217
+ C++L +L L+ N
Sbjct: 680 QLFYCRKLRYLDLSHN 695
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
Query: 11 NHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX 69
NHI + I+ RL LN +I +IP L+ C ++ +L L N ++ P +
Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 708
Query: 70 XXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE 129
P E+ + L L+L N L L +G+L L L+
Sbjct: 709 NLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLEC 768
Query: 130 IPKEIGKLTQLDTFGARGNE--LKTIPEEM 157
+P E+G+ L G E T+P E+
Sbjct: 769 LPVELGECPLLKRSGLVVEEDLFNTLPPEV 798
>BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 74.5 bits (175), Expect = 5e-13
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 7/220 (3%)
Query: 4 ILKFIRENHILALIEQAIAKKKSR--LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVF 61
+++ E L + + + ++ R L + E +P L +++ LH+ +
Sbjct: 39 LVRIWEERVSLTKLREKVTREDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKI 98
Query: 62 PVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGD---LEKLE 118
P P IG L L L LSYN + + E+ + LEKLE
Sbjct: 99 PEFIGRFQNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLE 158
Query: 119 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD 178
NR + ++P+E+ L +L N+ TIP + ++ L WL + +N++E LPD
Sbjct: 159 LA-VNR-DICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPD 216
Query: 179 TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
T++RM L L+ N + P +I K L L L++N+
Sbjct: 217 TIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNK 256
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX-XXPT 86
L L+ I+EIP + ++ L L NKI P E P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
E+ NL L +L+LS N + + ++ LE L+++P I ++ L T +
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
NE+ +P+ ++++ L L L NN+++ +P M+ M L N R+N L+
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Score = 55.2 bits (127), Expect = 3e-07
Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 1/168 (0%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIP- 109
L L +N IS P P E+ N +L L L+ N +P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 110 EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLE 169
E+ +L KL + IP + + L+ N+L+ +P+ + + L L L+
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 170 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+I LP T+ M L L NN+L+ P + + L F+ N
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
>AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein.
Length = 546
Score = 74.5 bits (175), Expect = 5e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 391 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 450
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 451 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 510
Query: 205 KC 206
+C
Sbjct: 511 EC 512
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEI---PKEIGKLTQLD 141
P I +L NL ++L N L I EI + L C ++ I P +IG LT L+
Sbjct: 343 PHSIFSLHNLQEIDLKDNNLKT-IEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLE 401
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+++ IP ++ KLR+L L +N + LP + + L + + NR+E P
Sbjct: 402 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 461
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMP 245
+ +C++L L L +N +L E T T + G+ +P
Sbjct: 462 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 506
Score = 56.0 bits (129), Expect = 2e-07
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
T++G +++N L VL + ++ +L +LE C+ L+ IP I L L
Sbjct: 299 TDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCD---LERIPHSIFSLHNLQEI 355
Query: 144 GARGNELKTIPE--EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N LKTI E L +L L L N I +P + +T L L N++E+ P+
Sbjct: 356 DLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPT 415
Query: 202 SILKCKELMFLQLNSN 217
+ C++L +L L+ N
Sbjct: 416 QLFYCRKLRYLDLSHN 431
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
Query: 11 NHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX 69
NHI + I+ RL LN +I +IP L+ C ++ +L L N ++ P +
Sbjct: 385 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 444
Query: 70 XXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE 129
P E+ + L L+L N L L +G+L L L+
Sbjct: 445 NLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLEC 504
Query: 130 IPKEIGKLTQLDTFGARGNE--LKTIPEEM 157
+P E+G+ L G E T+P E+
Sbjct: 505 LPVELGECPLLKRSGLVVEEDLFNTLPPEV 534
>AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein.
Length = 335
Score = 74.5 bits (175), Expect = 5e-13
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 7/220 (3%)
Query: 4 ILKFIRENHILALIEQAIAKKKSR--LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVF 61
+++ E L + + + ++ R L + E +P L +++ LH+ +
Sbjct: 39 LVRIWEERVSLTKLREKVTREDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKI 98
Query: 62 PVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGD---LEKLE 118
P P IG L L L LSYN + + E+ + LEKLE
Sbjct: 99 PEFIGRFQNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLE 158
Query: 119 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD 178
NR + ++P+E+ L +L N+ TIP + ++ L WL + +N++E LPD
Sbjct: 159 LA-VNR-DICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPD 216
Query: 179 TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
T++RM L L+ N + P +I K L L L++N+
Sbjct: 217 TIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNK 256
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX-XXPT 86
L L+ I+EIP + ++ L L NKI P E P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
E+ NL L +L+LS N + + ++ LE L+++P I ++ L T +
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
NE+ +P+ ++++ L L L NN+++ +P M+ M L N R+N L+
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Score = 55.2 bits (127), Expect = 3e-07
Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 1/168 (0%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIP- 109
L L +N IS P P E+ N +L L L+ N +P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 110 EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLE 169
E+ +L KL + IP + + L+ N+L+ +P+ + + L L L+
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 170 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+I LP T+ M L L NN+L+ P + + L F+ N
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
>AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich
repeat-containing 8 protein.
Length = 810
Score = 74.5 bits (175), Expect = 5e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 655 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 714
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 715 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 205 KC 206
+C
Sbjct: 775 EC 776
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEI---PKEIGKLTQLD 141
P I +L NL ++L N L I EI + L C ++ I P +IG LT L+
Sbjct: 607 PHSIFSLHNLQEIDLKDNNLKT-IEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLE 665
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+++ IP ++ KLR+L L +N + LP + + L + + NR+E P
Sbjct: 666 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 725
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMP 245
+ +C++L L L +N +L E T T + G+ +P
Sbjct: 726 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 770
Score = 56.0 bits (129), Expect = 2e-07
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
T++G +++N L VL + ++ +L +LE C+ L+ IP I L L
Sbjct: 563 TDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCD---LERIPHSIFSLHNLQEI 619
Query: 144 GARGNELKTIPE--EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N LKTI E L +L L L N I +P + +T L L N++E+ P+
Sbjct: 620 DLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPT 679
Query: 202 SILKCKELMFLQLNSN 217
+ C++L +L L+ N
Sbjct: 680 QLFYCRKLRYLDLSHN 695
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
Query: 11 NHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX 69
NHI + I+ RL LN +I +IP L+ C ++ +L L N ++ P +
Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 708
Query: 70 XXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE 129
P E+ + L L+L N L L +G+L L L+
Sbjct: 709 NLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLEC 768
Query: 130 IPKEIGKLTQLDTFGARGNE--LKTIPEEM 157
+P E+G+ L G E T+P E+
Sbjct: 769 LPVELGECPLLKRSGLVVEEDLFNTLPPEV 798
>AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 74.5 bits (175), Expect = 5e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 655 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 714
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 715 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 205 KC 206
+C
Sbjct: 775 EC 776
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEI---PKEIGKLTQLD 141
P I +L NL ++L N L I EI + L C ++ I P +IG LT L+
Sbjct: 607 PHSIFSLHNLQEIDLKDNNLKT-IEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLE 665
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+++ IP ++ KLR+L L +N + LP + + L + + NR+E P
Sbjct: 666 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 725
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMP 245
+ +C++L L L +N +L E T T + G+ +P
Sbjct: 726 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 770
Score = 56.0 bits (129), Expect = 2e-07
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
T++G +++N L VL + ++ +L +LE C+ L+ IP I L L
Sbjct: 563 TDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCD---LERIPHSIFSLHNLQEI 619
Query: 144 GARGNELKTIPE--EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N LKTI E L +L L L N I +P + +T L L N++E+ P+
Sbjct: 620 DLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPT 679
Query: 202 SILKCKELMFLQLNSN 217
+ C++L +L L+ N
Sbjct: 680 QLFYCRKLRYLDLSHN 695
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
Query: 11 NHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX 69
NHI + I+ RL LN +I +IP L+ C ++ +L L N ++ P +
Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 708
Query: 70 XXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE 129
P E+ + L L+L N L L +G+L L L+
Sbjct: 709 NLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLEC 768
Query: 130 IPKEIGKLTQLDTFGARGNE--LKTIPEEM 157
+P E+G+ L G E T+P E+
Sbjct: 769 LPVELGECPLLKRSGLVVEEDLFNTLPPEV 798
>AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 339
Score = 74.5 bits (175), Expect = 5e-13
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 7/220 (3%)
Query: 4 ILKFIRENHILALIEQAIAKKKSR--LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVF 61
+++ E L + + + ++ R L + E +P L +++ LH+ +
Sbjct: 39 LVRIWEERVSLTKLREKVTREDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKI 98
Query: 62 PVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGD---LEKLE 118
P P IG L L L LSYN + + E+ + LEKLE
Sbjct: 99 PEFIGRFQNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLE 158
Query: 119 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD 178
NR + ++P+E+ L +L N+ TIP + ++ L WL + +N++E LPD
Sbjct: 159 LA-VNR-DICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPD 216
Query: 179 TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
T++RM L L+ N + P +I K L L L++N+
Sbjct: 217 TIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNK 256
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX-XXPT 86
L L+ I+EIP + ++ L L NKI P E P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
E+ NL L +L+LS N + + ++ LE L+++P I ++ L T +
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
NE+ +P+ ++++ L L L NN+++ +P M+ M L N R+N L+
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Score = 55.2 bits (127), Expect = 3e-07
Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 1/168 (0%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIP- 109
L L +N IS P P E+ N +L L L+ N +P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 110 EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLE 169
E+ +L KL + IP + + L+ N+L+ +P+ + + L L L+
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 170 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+I LP T+ M L L NN+L+ P + + L F+ N
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
>AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 74.5 bits (175), Expect = 5e-13
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 7/220 (3%)
Query: 4 ILKFIRENHILALIEQAIAKKKSR--LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVF 61
+++ E L + + + ++ R L + E +P L +++ LH+ +
Sbjct: 39 LVRIWEERVSLTKLREKVTREDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKI 98
Query: 62 PVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGD---LEKLE 118
P P IG L L L LSYN + + E+ + LEKLE
Sbjct: 99 PEFIGRFQNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLE 158
Query: 119 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD 178
NR + ++P+E+ L +L N+ TIP + ++ L WL + +N++E LPD
Sbjct: 159 LA-VNR-DICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPD 216
Query: 179 TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
T++RM L L+ N + P +I K L L L++N+
Sbjct: 217 TIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNK 256
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX-XXPT 86
L L+ I+EIP + ++ L L NKI P E P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
E+ NL L +L+LS N + + ++ LE L+++P I ++ L T +
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
NE+ +P+ ++++ L L L NN+++ +P M+ M L N R+N L+
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Score = 55.2 bits (127), Expect = 3e-07
Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 1/168 (0%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIP- 109
L L +N IS P P E+ N +L L L+ N +P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 110 EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLE 169
E+ +L KL + IP + + L+ N+L+ +P+ + + L L L+
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 170 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+I LP T+ M L L NN+L+ P + + L F+ N
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
>AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens
cDNA FLJ14589 fis, clone NT2RM4001876, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 474
Score = 74.5 bits (175), Expect = 5e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 319 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 378
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 379 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 438
Query: 205 KC 206
+C
Sbjct: 439 EC 440
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEI---PKEIGKLTQLD 141
P I +L NL ++L N L I EI + L C ++ I P +IG LT L+
Sbjct: 271 PHSIFSLHNLQEIDLKDNNLKT-IEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLE 329
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+++ IP ++ KLR+L L +N + LP + + L + + NR+E P
Sbjct: 330 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 389
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMP 245
+ +C++L L L +N +L E T T + G+ +P
Sbjct: 390 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 434
Score = 56.0 bits (129), Expect = 2e-07
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
T++G +++N L VL + ++ +L +LE C+ L+ IP I L L
Sbjct: 227 TDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCD---LERIPHSIFSLHNLQEI 283
Query: 144 GARGNELKTIPE--EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N LKTI E L +L L L N I +P + +T L L N++E+ P+
Sbjct: 284 DLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPT 343
Query: 202 SILKCKELMFLQLNSN 217
+ C++L +L L+ N
Sbjct: 344 QLFYCRKLRYLDLSHN 359
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
Query: 11 NHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX 69
NHI + I+ RL LN +I +IP L+ C ++ +L L N ++ P +
Sbjct: 313 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 372
Query: 70 XXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE 129
P E+ + L L+L N L L +G+L L L+
Sbjct: 373 NLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLEC 432
Query: 130 IPKEIGKLTQLDTFGARGNE--LKTIPEEM 157
+P E+G+ L G E T+P E+
Sbjct: 433 LPVELGECPLLKRSGLVVEEDLFNTLPPEV 462
>AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens
cDNA FLJ10337 fis, clone NT2RM2000714, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 221
Score = 74.5 bits (175), Expect = 5e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 66 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 125
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 126 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 185
Query: 205 KC 206
+C
Sbjct: 186 EC 187
Score = 66.9 bits (156), Expect = 1e-10
Identities = 46/165 (27%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEI---PKEIGKLTQLD 141
P I +L NL ++L + L I EI + L C ++ I P +IG LT L+
Sbjct: 18 PHSIFSLHNLQEIDLKDDNLKT-IEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLE 76
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+++ IP ++ KLR+L L +N + LP + + L + + NR+E P
Sbjct: 77 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 136
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMP 245
+ +C++L L L +N +L E T T + G+ +P
Sbjct: 137 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 181
Score = 51.2 bits (117), Expect = 6e-06
Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE--EMTSLAKLRWLTL 168
+ +L +LE C+ L+ IP I L L + + LKTI E L +L L L
Sbjct: 1 MANLTELELIRCD---LERIPHSIFSLHNLQEIDLKDDNLKTIEEIISFQHLHRLTCLKL 57
Query: 169 ENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N I +P + +T L L N++E+ P+ + C++L +L L+ N
Sbjct: 58 WYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHN 106
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
Query: 11 NHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX 69
NHI + I+ RL LN +I +IP L+ C ++ +L L N ++ P +
Sbjct: 60 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 119
Query: 70 XXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE 129
P E+ + L L+L N L L +G+L L L+
Sbjct: 120 NLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLEC 179
Query: 130 IPKEIGKLTQLDTFGARGNE--LKTIPEEM 157
+P E+G+ L G E T+P E+
Sbjct: 180 LPVELGECPLLKRSGLVVEEDLFNTLPPEV 209
>AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein.
Length = 811
Score = 74.5 bits (175), Expect = 5e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 656 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 715
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 716 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 775
Query: 205 KC 206
+C
Sbjct: 776 EC 777
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEI---PKEIGKLTQLD 141
P I +L NL ++L N L I EI + L C ++ I P +IG LT L+
Sbjct: 608 PHSIFSLHNLQEIDLKDNNLKT-IEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLE 666
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+++ IP ++ KLR+L L +N + LP + + L + + NR+E P
Sbjct: 667 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 726
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMP 245
+ +C++L L L +N +L E T T + G+ +P
Sbjct: 727 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 771
Score = 56.0 bits (129), Expect = 2e-07
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
T++G +++N L VL + ++ +L +LE C+ L+ IP I L L
Sbjct: 564 TDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCD---LERIPHSIFSLHNLQEI 620
Query: 144 GARGNELKTIPE--EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N LKTI E L +L L L N I +P + +T L L N++E+ P+
Sbjct: 621 DLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPT 680
Query: 202 SILKCKELMFLQLNSN 217
+ C++L +L L+ N
Sbjct: 681 QLFYCRKLRYLDLSHN 696
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
Query: 11 NHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX 69
NHI + I+ RL LN +I +IP L+ C ++ +L L N ++ P +
Sbjct: 650 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 709
Query: 70 XXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE 129
P E+ + L L+L N L L +G+L L L+
Sbjct: 710 NLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLEC 769
Query: 130 IPKEIGKLTQLDTFGARGNE--LKTIPEEM 157
+P E+G+ L G E T+P E+
Sbjct: 770 LPVELGECPLLKRSGLVVEEDLFNTLPPEV 799
>AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ90242 fis, clone NT2RM2001626, highly similar to
Leucine-rich repeat-containing protein 8 precursor. ).
Length = 546
Score = 73.7 bits (173), Expect = 9e-13
Identities = 41/122 (33%), Positives = 60/122 (49%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 391 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 450
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N ++T+P E+ KLR L L NN + +LP + +T L LR NRLE P +
Sbjct: 451 ITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVELG 510
Query: 205 KC 206
+C
Sbjct: 511 EC 512
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEI---PKEIGKLTQLD 141
P I +L NL ++L N L I EI + L C ++ I P +IG LT L+
Sbjct: 343 PHSIFSLHNLQEIDLKDNNLKT-IEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLE 401
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N+++ IP ++ KLR+L L +N + LP + + L + + NR+E P
Sbjct: 402 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 461
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMP 245
+ +C++L L L +N +L E T T + G+ +P
Sbjct: 462 ELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLP 506
Score = 56.0 bits (129), Expect = 2e-07
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
T++G +++N L VL + ++ +L +LE C+ L+ IP I L L
Sbjct: 299 TDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCD---LERIPHSIFSLHNLQEI 355
Query: 144 GARGNELKTIPE--EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N LKTI E L +L L L N I +P + +T L L N++E+ P+
Sbjct: 356 DLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPT 415
Query: 202 SILKCKELMFLQLNSN 217
+ C++L +L L+ N
Sbjct: 416 QLFYCRKLRYLDLSHN 431
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
Query: 11 NHILAL-IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXX 69
NHI + I+ RL LN +I +IP L+ C ++ +L L N ++ P +
Sbjct: 385 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 444
Query: 70 XXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE 129
P E+ + L L+L N L L +G+L L L+
Sbjct: 445 NLQNLAITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLEC 504
Query: 130 IPKEIGKLTQLDTFGARGNE--LKTIPEEM 157
+P E+G+ L G E T+P E+
Sbjct: 505 LPVELGECPLLKRSGLVVEEDLFNTLPPEV 534
>BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 4 protein.
Length = 683
Score = 73.3 bits (172), Expect = 1e-12
Identities = 45/130 (34%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+GNL L LNLS N L++L P I L L + L +P +IG L L
Sbjct: 110 LGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSS 168
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
NEL+++P E+ L+ LR L + NQ+ TLP+ + + LV + NR+ + P S + +
Sbjct: 169 NELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDL-PLVRLDFSCNRVSRIPVSFCRLR 227
Query: 208 ELMFLQLNSN 217
L + L+SN
Sbjct: 228 HLQVILLDSN 237
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 9/150 (6%)
Query: 28 LSLNGFEITEIPGLLYTC-LEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L+L+ +++ +P Y C L + L + NK+ P + P+
Sbjct: 119 LNLSRNQLSLLPP--YICQLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPS 176
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGA 145
E+ L +L +LN+ N L+ L E+GDL + F CNR+ IP +L L
Sbjct: 177 ELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNRV--SRIPVSFCRLRHLQVILL 234
Query: 146 RGNELKTIPEEMTSLAKL---RWLTLENNQ 172
N L++ P ++ KL ++L+ E Q
Sbjct: 235 DSNPLQSPPAQVCLKGKLHIFKYLSTEAGQ 264
Score = 38.3 bits (85), Expect = 0.043
Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 8/148 (5%)
Query: 133 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 192
++ +TQ D N +PE L L L+L +N + L + +TAL + NL
Sbjct: 66 DLSDITQADL---SRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLS 122
Query: 193 NNRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDE-ATTQTSDSNGSLASAMPSTSRVY 251
N+L P I + L L +++N+ AL + + D + + ++P S +
Sbjct: 123 RNQLSLLPPYICQL-PLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLP--SELC 179
Query: 252 GAQALA-LNATALRLPAAPEHQHPDPLV 278
G +L LN +L PE PLV
Sbjct: 180 GLSSLRDLNVRRNQLSTLPEELGDLPLV 207
>BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein.
Length = 580
Score = 73.3 bits (172), Expect = 1e-12
Identities = 45/130 (34%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+GNL L LNLS N L++L P I L L + L +P +IG L L
Sbjct: 7 LGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSS 65
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
NEL+++P E+ L+ LR L + NQ+ TLP+ + + LV + NR+ + P S + +
Sbjct: 66 NELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDL-PLVRLDFSCNRVSRIPVSFCRLR 124
Query: 208 ELMFLQLNSN 217
L + L+SN
Sbjct: 125 HLQVILLDSN 134
Score = 47.2 bits (107), Expect = 9e-05
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 2/136 (1%)
Query: 134 IGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRN 193
+G LT L N+L +P + L LR L + NN++ LP + + +L ++ +
Sbjct: 7 LGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSS 65
Query: 194 NRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMP-STSRVYG 252
N L+ PS + L L + NQ L + + D + + S +P S R+
Sbjct: 66 NELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNRVSRIPVSFCRLRH 125
Query: 253 AQALALNATALRLPAA 268
Q + L++ L+ P A
Sbjct: 126 LQVILLDSNPLQSPPA 141
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 9/150 (6%)
Query: 28 LSLNGFEITEIPGLLYTC-LEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L+L+ +++ +P Y C L + L + NK+ P + P+
Sbjct: 16 LNLSRNQLSLLPP--YICQLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPS 73
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGA 145
E+ L +L +LN+ N L+ L E+GDL + F CNR+ IP +L L
Sbjct: 74 ELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNRV--SRIPVSFCRLRHLQVILL 131
Query: 146 RGNELKTIPEEMTSLAKL---RWLTLENNQ 172
N L++ P ++ KL ++L+ E Q
Sbjct: 132 DSNPLQSPPAQVCLKGKLHIFKYLSTEAGQ 161
>AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ10775 fis, clone NT2RP4000312, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 183
Score = 73.3 bits (172), Expect = 1e-12
Identities = 47/176 (26%), Positives = 74/176 (42%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ EI EIP + C ++ N ++ P P
Sbjct: 6 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 65
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 66 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 125
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P +
Sbjct: 126 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGL 181
Score = 71.3 bits (167), Expect = 5e-12
Identities = 46/149 (30%), Positives = 70/149 (46%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P I K L + S NPL L +L+ L N I L+ +P+ IG L L +
Sbjct: 17 PESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLE 76
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
R N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P I
Sbjct: 77 LRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIG 136
Query: 205 KCKELMFLQLNSNQEHALIKYTDEATTQT 233
K L+ L ++ N+ L + T+ T
Sbjct: 137 NLKNLLCLDVSENRLERLPEEISGLTSLT 165
Score = 61.7 bits (143), Expect = 4e-09
Identities = 33/97 (34%), Positives = 50/97 (51%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L+ L L+L N + L IG L L+ W + L E+P+EIG L L
Sbjct: 86 PDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLD 145
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMD 181
N L+ +PEE++ L L L + N +ET+PD ++
Sbjct: 146 VSENRLERLPEEISGLTSLTDLVISQNLLETIPDGLE 182
Score = 59.7 bits (138), Expect = 2e-08
Identities = 41/172 (23%), Positives = 73/172 (42%)
Query: 46 LEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLN 105
+++ L + +N+I P P L+NL L+++ L
Sbjct: 1 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 60
Query: 106 VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRW 165
L IG+L L + L +P + +L +L+ NE+ +PE + +L L+
Sbjct: 61 SLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKD 120
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L L+ NQ+ LP + + L+ ++ NRLE+ P I L L ++ N
Sbjct: 121 LWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQN 172
Score = 50.4 bits (115), Expect = 1e-05
Identities = 34/125 (27%), Positives = 57/125 (45%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
LV L++S N + + I + L+ + L +P+ +L L L+++
Sbjct: 3 LVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSL 62
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
PE + +L L L L N + LPD++ ++ L +L NN + P SI L L
Sbjct: 63 PENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLW 122
Query: 214 LNSNQ 218
L+ NQ
Sbjct: 123 LDGNQ 127
Score = 49.6 bits (113), Expect = 2e-05
Identities = 28/100 (28%), Positives = 47/100 (47%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+R + EIP+ I L GN L +PE L L L++ + +++LP+ +
Sbjct: 9 SRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGN 68
Query: 183 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ L LR N L P S+ + + L L L +N+ + L
Sbjct: 69 LYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNL 108
>AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal
protein protein.
Length = 832
Score = 73.3 bits (172), Expect = 1e-12
Identities = 45/130 (34%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+GNL L LNLS N L++L P I L L + L +P +IG L L
Sbjct: 110 LGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSS 168
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
NEL+++P E+ L+ LR L + NQ+ TLP+ + + LV + NR+ + P S + +
Sbjct: 169 NELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDL-PLVRLDFSCNRVSRIPVSFCRLR 227
Query: 208 ELMFLQLNSN 217
L + L+SN
Sbjct: 228 HLQVILLDSN 237
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 9/150 (6%)
Query: 28 LSLNGFEITEIPGLLYTC-LEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L+L+ +++ +P Y C L + L + NK+ P + P+
Sbjct: 119 LNLSRNQLSLLPP--YICQLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPS 176
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGA 145
E+ L +L +LN+ N L+ L E+GDL + F CNR+ IP +L L
Sbjct: 177 ELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNRV--SRIPVSFCRLRHLQVILL 234
Query: 146 RGNELKTIPEEMTSLAKL---RWLTLENNQ 172
N L++ P ++ KL ++L+ E Q
Sbjct: 235 DSNPLQSPPAQVCLKGKLHIFKYLSTEAGQ 264
Score = 38.3 bits (85), Expect = 0.043
Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 8/148 (5%)
Query: 133 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 192
++ +TQ D N +PE L L L+L +N + L + +TAL + NL
Sbjct: 66 DLSDITQADL---SRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLS 122
Query: 193 NNRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDE-ATTQTSDSNGSLASAMPSTSRVY 251
N+L P I + L L +++N+ AL + + D + + ++P S +
Sbjct: 123 RNQLSLLPPYICQL-PLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLP--SELC 179
Query: 252 GAQALA-LNATALRLPAAPEHQHPDPLV 278
G +L LN +L PE PLV
Sbjct: 180 GLSSLRDLNVRRNQLSTLPEELGDLPLV 207
>BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 72.9 bits (171), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFP--VEXXXXXXXXXXXXXXXXXXX 83
+ L L E+ IP +++ ++ L L N I +
Sbjct: 638 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 697
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 698 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 757
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 758 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 817
Query: 204 LKCKEL 209
+C+ L
Sbjct: 818 GQCRML 823
Score = 60.5 bits (140), Expect = 9e-09
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 141
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 651 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 709
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 710 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPK 769
Query: 202 SILKCKELMFLQLNSN 217
+ KC +L L L N
Sbjct: 770 QLFKCIKLRTLNLGQN 785
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/157 (25%), Positives = 73/157 (46%), Gaps = 2/157 (1%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ + L L +I IP + +E LY NK+ PV
Sbjct: 683 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 742
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P EIG L+NL +L+++ N +++L ++ KL + + +P+++G+L+QL
Sbjct: 743 MIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQ 802
Query: 143 FGARGNELKTIPEEM--TSLAKLRWLTLENNQIETLP 177
+GN L +P ++ + K L +E++ +TLP
Sbjct: 803 LELKGNCLDRLPAQLGQCRMLKKSGLVVEDHLFDTLP 839
Score = 36.7 bits (81), Expect = 0.13
Identities = 21/77 (27%), Positives = 36/77 (46%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N++ TIP +T + L L NN++E+LP + + L ++ N + P I +
Sbjct: 693 NKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQ 752
Query: 208 ELMFLQLNSNQEHALIK 224
L L + N+ L K
Sbjct: 753 NLQHLHITGNKVDILPK 769
>AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein.
Length = 501
Score = 72.9 bits (171), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFP--VEXXXXXXXXXXXXXXXXXXX 83
+ L L E+ IP +++ ++ L L N I +
Sbjct: 281 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 340
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 341 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 400
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 401 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 460
Query: 204 LKCKEL 209
+C+ L
Sbjct: 461 GQCRML 466
Score = 60.5 bits (140), Expect = 9e-09
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 141
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 294 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 352
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 353 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPK 412
Query: 202 SILKCKELMFLQLNSN 217
+ KC +L L L N
Sbjct: 413 QLFKCIKLRTLNLGQN 428
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/157 (25%), Positives = 73/157 (46%), Gaps = 2/157 (1%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ + L L +I IP + +E LY NK+ PV
Sbjct: 326 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 385
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P EIG L+NL +L+++ N +++L ++ KL + + +P+++G+L+QL
Sbjct: 386 MIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQ 445
Query: 143 FGARGNELKTIPEEM--TSLAKLRWLTLENNQIETLP 177
+GN L +P ++ + K L +E++ +TLP
Sbjct: 446 LELKGNCLDRLPAQLGQCRMLKKSGLVVEDHLFDTLP 482
Score = 36.7 bits (81), Expect = 0.13
Identities = 21/77 (27%), Positives = 36/77 (46%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N++ TIP +T + L L NN++E+LP + + L ++ N + P I +
Sbjct: 336 NKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQ 395
Query: 208 ELMFLQLNSNQEHALIK 224
L L + N+ L K
Sbjct: 396 NLQHLHITGNKVDILPK 412
>AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 72.9 bits (171), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFP--VEXXXXXXXXXXXXXXXXXXX 83
+ L L E+ IP +++ ++ L L N I +
Sbjct: 638 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 697
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 698 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 757
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 758 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 817
Query: 204 LKCKEL 209
+C+ L
Sbjct: 818 GQCRML 823
Score = 60.5 bits (140), Expect = 9e-09
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 141
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 651 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 709
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 710 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPK 769
Query: 202 SILKCKELMFLQLNSN 217
+ KC +L L L N
Sbjct: 770 QLFKCIKLRTLNLGQN 785
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/157 (25%), Positives = 73/157 (46%), Gaps = 2/157 (1%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ + L L +I IP + +E LY NK+ PV
Sbjct: 683 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 742
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P EIG L+NL +L+++ N +++L ++ KL + + +P+++G+L+QL
Sbjct: 743 MIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQ 802
Query: 143 FGARGNELKTIPEEM--TSLAKLRWLTLENNQIETLP 177
+GN L +P ++ + K L +E++ +TLP
Sbjct: 803 LELKGNCLDRLPAQLGQCRMLKKSGLVVEDHLFDTLP 839
Score = 36.7 bits (81), Expect = 0.13
Identities = 21/77 (27%), Positives = 36/77 (46%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N++ TIP +T + L L NN++E+LP + + L ++ N + P I +
Sbjct: 693 NKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQ 752
Query: 208 ELMFLQLNSNQEHALIK 224
L L + N+ L K
Sbjct: 753 NLQHLHITGNKVDILPK 769
>AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat
containing 5 variant protein.
Length = 671
Score = 72.9 bits (171), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFP--VEXXXXXXXXXXXXXXXXXXX 83
+ L L E+ IP +++ ++ L L N I +
Sbjct: 451 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 510
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 511 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQDLQHL 570
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 571 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 630
Query: 204 LKCKEL 209
+C+ L
Sbjct: 631 GQCRML 636
Score = 60.5 bits (140), Expect = 9e-09
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 141
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 464 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 522
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 523 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQDLQHLHITGNKVDILPK 582
Query: 202 SILKCKELMFLQLNSN 217
+ KC +L L L N
Sbjct: 583 QLFKCIKLRTLNLGQN 598
Score = 57.2 bits (132), Expect = 9e-08
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 2/157 (1%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ + L L +I IP + +E LY NK+ PV
Sbjct: 496 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 555
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P EIG L++L +L+++ N +++L ++ KL + + +P+++G+L+QL
Sbjct: 556 MIPIEIGLLQDLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQ 615
Query: 143 FGARGNELKTIPEEM--TSLAKLRWLTLENNQIETLP 177
+GN L +P ++ + K L +E++ +TLP
Sbjct: 616 LELKGNCLDRLPAQLGQCRMLKKSGLVVEDHLFDTLP 652
Score = 37.5 bits (83), Expect = 0.075
Identities = 21/77 (27%), Positives = 37/77 (48%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N++ TIP +T + L L NN++E+LP + + L ++ N + P I +
Sbjct: 506 NKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQ 565
Query: 208 ELMFLQLNSNQEHALIK 224
+L L + N+ L K
Sbjct: 566 DLQHLHITGNKVDILPK 582
>AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ10470 fis, clone NT2RP2000032, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 682
Score = 72.9 bits (171), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFP--VEXXXXXXXXXXXXXXXXXXX 83
+ L L E+ IP +++ ++ L L N I +
Sbjct: 462 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 521
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 522 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 581
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 582 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 641
Query: 204 LKCKEL 209
+C+ L
Sbjct: 642 GQCRML 647
Score = 60.5 bits (140), Expect = 9e-09
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 141
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 475 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 533
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 534 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPK 593
Query: 202 SILKCKELMFLQLNSN 217
+ KC +L L L N
Sbjct: 594 QLFKCIKLRTLNLGQN 609
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/157 (25%), Positives = 73/157 (46%), Gaps = 2/157 (1%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ + L L +I IP + +E LY NK+ PV
Sbjct: 507 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 566
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P EIG L+NL +L+++ N +++L ++ KL + + +P+++G+L+QL
Sbjct: 567 MIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQ 626
Query: 143 FGARGNELKTIPEEM--TSLAKLRWLTLENNQIETLP 177
+GN L +P ++ + K L +E++ +TLP
Sbjct: 627 LELKGNCLDRLPAQLGQCRMLKKSGLVVEDHLFDTLP 663
Score = 36.7 bits (81), Expect = 0.13
Identities = 21/77 (27%), Positives = 36/77 (46%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N++ TIP +T + L L NN++E+LP + + L ++ N + P I +
Sbjct: 517 NKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQ 576
Query: 208 ELMFLQLNSNQEHALIK 224
L L + N+ L K
Sbjct: 577 NLQHLHITGNKVDILPK 593
>BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein.
Length = 532
Score = 72.1 bits (169), Expect = 3e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 382 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 441
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 442 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 501
Query: 205 KC 206
C
Sbjct: 502 NC 503
Score = 64.5 bits (150), Expect = 6e-10
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 8 IRENHILALIEQAIA----KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV 63
+++NH+ + IE+ ++ +K L L +I +P + +E LYL NK+ P
Sbjct: 348 LKDNHLRS-IEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPS 406
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN 123
+ P E+G L+NL +L LSYN L L E+ KL
Sbjct: 407 QLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLG 466
Query: 124 RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR--WLTLENNQIETLP-DTM 180
L ++ +G L L +GN L+ +PEE+ + L+ L +E+ + LP +
Sbjct: 467 DNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQGLPAEVR 526
Query: 181 DRM 183
D+M
Sbjct: 527 DKM 529
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 121 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 374 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 431
Query: 181 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
+ L H L N LE P + C++L L L NQ
Sbjct: 432 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQ 469
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Query: 45 CLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 104
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 365 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 424
Query: 105 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 164
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 425 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 484
Query: 165 WLTLENNQIETLPDTMDRMTALVHCNL 191
L L+ N++E LP+ + L L
Sbjct: 485 RLELKGNRLEALPEELGNCGGLKKAGL 511
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/131 (26%), Positives = 60/131 (45%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+ LV L L +N + + + L LE + + L+ +P ++G + L N L
Sbjct: 366 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLH 425
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P E+ L L+ L L N +E LP+ + L L +N+L Q + + L
Sbjct: 426 SLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSR 485
Query: 212 LQLNSNQEHAL 222
L+L N+ AL
Sbjct: 486 LELKGNRLEAL 496
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 165
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 314 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 370
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N H+L
Sbjct: 371 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL 427
>BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat
containing 8 family, member E protein.
Length = 796
Score = 72.1 bits (169), Expect = 3e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 646 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 705
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 706 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 765
Query: 205 KC 206
C
Sbjct: 766 NC 767
Score = 64.5 bits (150), Expect = 6e-10
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 8 IRENHILALIEQAIA----KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV 63
+++NH+ + IE+ ++ +K L L +I +P + +E LYL NK+ P
Sbjct: 612 LKDNHLRS-IEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPS 670
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN 123
+ P E+G L+NL +L LSYN L L E+ KL
Sbjct: 671 QLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLG 730
Query: 124 RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR--WLTLENNQIETLP-DTM 180
L ++ +G L L +GN L+ +PEE+ + L+ L +E+ + LP +
Sbjct: 731 DNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQGLPAEVR 790
Query: 181 DRM 183
D+M
Sbjct: 791 DKM 793
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 121 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 638 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 695
Query: 181 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
+ L H L N LE P + C++L L L NQ
Sbjct: 696 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQ 733
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Query: 45 CLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 104
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 629 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 688
Query: 105 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 164
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 689 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 748
Query: 165 WLTLENNQIETLPDTMDRMTALVHCNL 191
L L+ N++E LP+ + L L
Sbjct: 749 RLELKGNRLEALPEELGNCGGLKKAGL 775
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/131 (26%), Positives = 60/131 (45%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+ LV L L +N + + + L LE + + L+ +P ++G + L N L
Sbjct: 630 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLH 689
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P E+ L L+ L L N +E LP+ + L L +N+L Q + + L
Sbjct: 690 SLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSR 749
Query: 212 LQLNSNQEHAL 222
L+L N+ AL
Sbjct: 750 LELKGNRLEAL 760
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 165
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 578 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 634
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N H+L
Sbjct: 635 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL 691
>BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein.
Length = 592
Score = 72.1 bits (169), Expect = 3e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 442 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 501
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 502 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 561
Query: 205 KC 206
C
Sbjct: 562 NC 563
Score = 64.5 bits (150), Expect = 6e-10
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 8 IRENHILALIEQAIA----KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV 63
+++NH+ + IE+ ++ +K L L +I +P + +E LYL NK+ P
Sbjct: 408 LKDNHLRS-IEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPS 466
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN 123
+ P E+G L+NL +L LSYN L L E+ KL
Sbjct: 467 QLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLG 526
Query: 124 RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR--WLTLENNQIETLP-DTM 180
L ++ +G L L +GN L+ +PEE+ + L+ L +E+ + LP +
Sbjct: 527 DNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQGLPAEVR 586
Query: 181 DRM 183
D+M
Sbjct: 587 DKM 589
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 121 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 434 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 491
Query: 181 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
+ L H L N LE P + C++L L L NQ
Sbjct: 492 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQ 529
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Query: 45 CLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 104
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 425 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 484
Query: 105 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 164
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 485 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 544
Query: 165 WLTLENNQIETLPDTMDRMTALVHCNL 191
L L+ N++E LP+ + L L
Sbjct: 545 RLELKGNRLEALPEELGNCGGLKKAGL 571
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/131 (26%), Positives = 60/131 (45%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+ LV L L +N + + + L LE + + L+ +P ++G + L N L
Sbjct: 426 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLH 485
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P E+ L L+ L L N +E LP+ + L L +N+L Q + + L
Sbjct: 486 SLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSR 545
Query: 212 LQLNSNQEHAL 222
L+L N+ AL
Sbjct: 546 LELKGNRLEAL 556
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 165
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 374 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 430
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N H+L
Sbjct: 431 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL 487
>AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein
protein.
Length = 622
Score = 72.1 bits (169), Expect = 3e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 472 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 531
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 532 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 591
Query: 205 KC 206
C
Sbjct: 592 NC 593
Score = 64.5 bits (150), Expect = 6e-10
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 8 IRENHILALIEQAIA----KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV 63
+++NH+ + IE+ ++ +K L L +I +P + +E LYL NK+ P
Sbjct: 438 LKDNHLRS-IEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPS 496
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN 123
+ P E+G L+NL +L LSYN L L E+ KL
Sbjct: 497 QLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLG 556
Query: 124 RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR--WLTLENNQIETLP-DTM 180
L ++ +G L L +GN L+ +PEE+ + L+ L +E+ + LP +
Sbjct: 557 DNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQGLPAEVR 616
Query: 181 DRM 183
D+M
Sbjct: 617 DKM 619
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 121 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 464 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 521
Query: 181 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
+ L H L N LE P + C++L L L NQ
Sbjct: 522 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQ 559
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Query: 45 CLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 104
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 455 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 514
Query: 105 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 164
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 515 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 574
Query: 165 WLTLENNQIETLPDTMDRMTALVHCNL 191
L L+ N++E LP+ + L L
Sbjct: 575 RLELKGNRLEALPEELGNCGGLKKAGL 601
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/131 (26%), Positives = 60/131 (45%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+ LV L L +N + + + L LE + + L+ +P ++G + L N L
Sbjct: 456 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLH 515
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P E+ L L+ L L N +E LP+ + L L +N+L Q + + L
Sbjct: 516 SLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSR 575
Query: 212 LQLNSNQEHAL 222
L+L N+ AL
Sbjct: 576 LELKGNRLEAL 586
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 165
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 404 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 460
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N H+L
Sbjct: 461 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL 517
>AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23420 fis, clone HEP22352. ).
Length = 444
Score = 72.1 bits (169), Expect = 3e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 294 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 353
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 354 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 413
Query: 205 KC 206
C
Sbjct: 414 NC 415
Score = 64.5 bits (150), Expect = 6e-10
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 8 IRENHILALIEQAIA----KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV 63
+++NH+ + IE+ ++ +K L L +I +P + +E LYL NK+ P
Sbjct: 260 LKDNHLRS-IEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPS 318
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN 123
+ P E+G L+NL +L LSYN L L E+ KL
Sbjct: 319 QLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLG 378
Query: 124 RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR--WLTLENNQIETLP-DTM 180
L ++ +G L L +GN L+ +PEE+ + L+ L +E+ + LP +
Sbjct: 379 DNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQGLPAEVR 438
Query: 181 DRM 183
D+M
Sbjct: 439 DKM 441
Score = 55.6 bits (128), Expect = 3e-07
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 121 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 286 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 343
Query: 181 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
+ L H L N LE P + C++L L L NQ
Sbjct: 344 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQ 381
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Query: 45 CLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 104
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 277 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 336
Query: 105 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 164
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 337 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 396
Query: 165 WLTLENNQIETLPDTMDRMTALVHCNL 191
L L+ N++E LP+ + L L
Sbjct: 397 RLELKGNRLEALPEELGNCGGLKKAGL 423
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/131 (26%), Positives = 60/131 (45%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
+ LV L L +N + + + L LE + + L+ +P ++G + L N L
Sbjct: 278 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLH 337
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
++P E+ L L+ L L N +E LP+ + L L +N+L Q + + L
Sbjct: 338 SLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSR 397
Query: 212 LQLNSNQEHAL 222
L+L N+ AL
Sbjct: 398 LELKGNRLEAL 408
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 165
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 226 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 282
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N H+L
Sbjct: 283 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL 339
>L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein.
Length = 277
Score = 70.9 bits (166), Expect = 7e-12
Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 4/192 (2%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGL--LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXX 73
L+E++ K + + ++ I+ + + L+T + L L NK+++ P
Sbjct: 8 LVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEV 67
Query: 74 XXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIP 131
PT+I +L+ L +LNL N LN L G L LE N + +P
Sbjct: 68 LNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLP 127
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNL 191
LT L N+ + +P ++ L KL+ L+L +N + +LP + +T L ++
Sbjct: 128 GNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHI 187
Query: 192 RNNRLEQFPSSI 203
+ NRL P +
Sbjct: 188 QGNRLTVLPPEL 199
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Query: 1 MSAILKFIRENHILALIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKI 58
+S I + + ++ L ++ IA+ K+ LN F +I E+P + + +++HL L N++
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 98
Query: 59 SVFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK 116
+ P P L L L LS N +L P+IG L K
Sbjct: 99 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 158
Query: 117 LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSL 160
L+ L +PKEIG+LTQL +GN L +P E+ +L
Sbjct: 159 LQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 60.5 bits (140), Expect = 9e-09
Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 207 KELMFLQLNSNQEHALIKYTDEAT 230
+L L L N +L K E T
Sbjct: 157 TKLQILSLRDNDLISLPKEIGELT 180
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 86 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 70.9 bits (166), Expect = 7e-12
Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 4/192 (2%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGL--LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXX 73
L+E++ K + + ++ I+ + + L+T + L L NK+++ P
Sbjct: 8 LVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEV 67
Query: 74 XXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIP 131
PT+I +L+ L +LNL N LN L G L LE N + +P
Sbjct: 68 LNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLP 127
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNL 191
LT L N+ + +P ++ L KL+ L+L +N + +LP + +T L ++
Sbjct: 128 GNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHI 187
Query: 192 RNNRLEQFPSSI 203
+ NRL P +
Sbjct: 188 QGNRLTVLPPEL 199
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Query: 1 MSAILKFIRENHILALIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKI 58
+S I + + ++ L ++ IA+ K+ LN F +I E+P + + +++HL L N++
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 98
Query: 59 SVFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK 116
+ P P L L L LS N +L P+IG L K
Sbjct: 99 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 158
Query: 117 LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSL 160
L+ L +PKEIG+LTQL +GN L +P E+ +L
Sbjct: 159 LQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 60.5 bits (140), Expect = 9e-09
Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 207 KELMFLQLNSNQEHALIKYTDEAT 230
+L L L N +L K E T
Sbjct: 157 TKLQILSLRDNDLISLPKEIGELT 180
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 86 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 70.9 bits (166), Expect = 7e-12
Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 4/192 (2%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGL--LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXX 73
L+E++ K + + ++ I+ + + L+T + L L NK+++ P
Sbjct: 8 LVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEV 67
Query: 74 XXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIP 131
PT+I +L+ L +LNL N LN L G L LE N + +P
Sbjct: 68 LNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLP 127
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNL 191
LT L N+ + +P ++ L KL+ L+L +N + +LP + +T L ++
Sbjct: 128 GNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHI 187
Query: 192 RNNRLEQFPSSI 203
+ NRL P +
Sbjct: 188 QGNRLTVLPPEL 199
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Query: 1 MSAILKFIRENHILALIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKI 58
+S I + + ++ L ++ IA+ K+ LN F +I E+P + + +++HL L N++
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 98
Query: 59 SVFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK 116
+ P P L L L LS N +L P+IG L K
Sbjct: 99 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 158
Query: 117 LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSL 160
L+ L +PKEIG+LTQL +GN L +P E+ +L
Sbjct: 159 LQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 60.5 bits (140), Expect = 9e-09
Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 207 KELMFLQLNSNQEHALIKYTDEAT 230
+L L L N +L K E T
Sbjct: 157 TKLQILSLRDNDLISLPKEIGELT 180
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 86 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 70.9 bits (166), Expect = 7e-12
Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 4/192 (2%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGL--LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXX 73
L+E++ K + + ++ I+ + + L+T + L L NK+++ P
Sbjct: 8 LVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEV 67
Query: 74 XXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIP 131
PT+I +L+ L +LNL N LN L G L LE N + +P
Sbjct: 68 LNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLP 127
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNL 191
LT L N+ + +P ++ L KL+ L+L +N + +LP + +T L ++
Sbjct: 128 GNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHI 187
Query: 192 RNNRLEQFPSSI 203
+ NRL P +
Sbjct: 188 QGNRLTVLPPEL 199
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Query: 1 MSAILKFIRENHILALIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKI 58
+S I + + ++ L ++ IA+ K+ LN F +I E+P + + +++HL L N++
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 98
Query: 59 SVFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK 116
+ P P L L L LS N +L P+IG L K
Sbjct: 99 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 158
Query: 117 LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSL 160
L+ L +PKEIG+LTQL +GN L +P E+ +L
Sbjct: 159 LQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 60.5 bits (140), Expect = 9e-09
Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 207 KELMFLQLNSNQEHALIKYTDEAT 230
+L L L N +L K E T
Sbjct: 157 TKLQILSLRDNDLISLPKEIGELT 180
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 86 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein.
Length = 277
Score = 70.9 bits (166), Expect = 7e-12
Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 4/192 (2%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGL--LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXX 73
L+E++ K + + ++ I+ + + L+T + L L NK+++ P
Sbjct: 8 LVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEV 67
Query: 74 XXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIP 131
PT+I +L+ L +LNL N LN L G L LE N + +P
Sbjct: 68 LNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLP 127
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNL 191
LT L N+ + +P ++ L KL+ L+L +N + +LP + +T L ++
Sbjct: 128 GNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHI 187
Query: 192 RNNRLEQFPSSI 203
+ NRL P +
Sbjct: 188 QGNRLTVLPPEL 199
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Query: 1 MSAILKFIRENHILALIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKI 58
+S I + + ++ L ++ IA+ K+ LN F +I E+P + + +++HL L N++
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 98
Query: 59 SVFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK 116
+ P P L L L LS N +L P+IG L K
Sbjct: 99 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 158
Query: 117 LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSL 160
L+ L +PKEIG+LTQL +GN L +P E+ +L
Sbjct: 159 LQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 60.5 bits (140), Expect = 9e-09
Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 207 KELMFLQLNSNQEHALIKYTDEAT 230
+L L L N +L K E T
Sbjct: 157 TKLQILSLRDNDLISLPKEIGELT 180
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 86 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 70.9 bits (166), Expect = 7e-12
Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 4/192 (2%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGL--LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXX 73
L+E++ K + + ++ I+ + + L+T + L L NK+++ P
Sbjct: 8 LVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEV 67
Query: 74 XXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIP 131
PT+I +L+ L +LNL N LN L G L LE N + +P
Sbjct: 68 LNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLP 127
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNL 191
LT L N+ + +P ++ L KL+ L+L +N + +LP + +T L ++
Sbjct: 128 GNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHI 187
Query: 192 RNNRLEQFPSSI 203
+ NRL P +
Sbjct: 188 QGNRLTVLPPEL 199
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Query: 1 MSAILKFIRENHILALIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKI 58
+S I + + ++ L ++ IA+ K+ LN F +I E+P + + +++HL L N++
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 98
Query: 59 SVFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK 116
+ P P L L L LS N +L P+IG L K
Sbjct: 99 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 158
Query: 117 LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSL 160
L+ L +PKEIG+LTQL +GN L +P E+ +L
Sbjct: 159 LQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 60.5 bits (140), Expect = 9e-09
Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 207 KELMFLQLNSNQEHALIKYTDEAT 230
+L L L N +L K E T
Sbjct: 157 TKLQILSLRDNDLISLPKEIGELT 180
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 86 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 70.9 bits (166), Expect = 7e-12
Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 4/192 (2%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGL--LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXX 73
L+E++ K + + ++ I+ + + L+T + L L NK+++ P
Sbjct: 8 LVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEV 67
Query: 74 XXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIP 131
PT+I +L+ L +LNL N LN L G L LE N + +P
Sbjct: 68 LNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLP 127
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNL 191
LT L N+ + +P ++ L KL+ L+L +N + +LP + +T L ++
Sbjct: 128 GNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHI 187
Query: 192 RNNRLEQFPSSI 203
+ NRL P +
Sbjct: 188 QGNRLTVLPPEL 199
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Query: 1 MSAILKFIRENHILALIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKI 58
+S I + + ++ L ++ IA+ K+ LN F +I E+P + + +++HL L N++
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 98
Query: 59 SVFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK 116
+ P P L L L LS N +L P+IG L K
Sbjct: 99 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 158
Query: 117 LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSL 160
L+ L +PKEIG+LTQL +GN L +P E+ +L
Sbjct: 159 LQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 60.5 bits (140), Expect = 9e-09
Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 207 KELMFLQLNSNQEHALIKYTDEAT 230
+L L L N +L K E T
Sbjct: 157 TKLQILSLRDNDLISLPKEIGELT 180
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 86 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 70.1 bits (164), Expect = 1e-11
Identities = 43/136 (31%), Positives = 67/136 (49%), Gaps = 3/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE--IPKEIGKLTQLDT 142
P E+ L+ L +L++S+N L L E+ L L A LK +P +I KL L
Sbjct: 49 PEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSV 108
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPS 201
N+L P E+ + + L L +N I+T+P+ + +T L++ +L NRLE P
Sbjct: 109 LDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPP 168
Query: 202 SILKCKELMFLQLNSN 217
+ + L L LN N
Sbjct: 169 QMRRLVHLQTLVLNGN 184
Score = 64.1 bits (149), Expect = 8e-10
Identities = 37/100 (37%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 97 LNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
LNLS N L L I L KL+ + N ++ +P IGKLT L+ F A N L+ +P
Sbjct: 274 LNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVP 333
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
E + KLR L L N + TLP+ + +T + ++R N
Sbjct: 334 ESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 373
Score = 61.7 bits (143), Expect = 4e-09
Identities = 41/136 (30%), Positives = 69/136 (50%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
PT + L NL +++LS N L +PE + L L + + E+ I + ++T
Sbjct: 216 PTSLEGLSNLADVDLSCNDLT-RVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETL 274
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIET--LPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L ++P + L+KL+ L L +N+++ LP + ++T L NN LE P
Sbjct: 275 NLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPE 334
Query: 202 SILKCKELMFLQLNSN 217
S+ +C +L L LN N
Sbjct: 335 SLCRCPKLRKLVLNKN 350
Score = 57.2 bits (132), Expect = 9e-08
Identities = 55/198 (27%), Positives = 82/198 (41%), Gaps = 6/198 (3%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX- 84
S L L+ ++TE P L + L L N I P +
Sbjct: 107 SVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESL 166
Query: 85 PTEIGNLKNLVNLNLSYNPLNVL----IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQL 140
P ++ L +L L L+ NPL +P + L+ L R +P + L+ L
Sbjct: 167 PPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQ-SNLPTSLEGLSNL 225
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N+L +PE + +L LR L L +NQI L +D+ + NL N+L P
Sbjct: 226 ADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLP 285
Query: 201 SSILKCKELMFLQLNSNQ 218
S+I K +L L LNSN+
Sbjct: 286 SAICKLSKLKKLYLNSNK 303
Score = 55.2 bits (127), Expect = 3e-07
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + +L L L+ L L E+ L+KLE + L + E+ L L
Sbjct: 26 PENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIV 85
Query: 145 ARGNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
AR N LK +P+++ L L L L +NQ+ P ++ ++ NL +N ++ P+
Sbjct: 86 ARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQ 145
Query: 203 I-LKCKELMFLQLNSNQEHAL 222
+ + +L++L L+ N+ +L
Sbjct: 146 LFINLTDLLYLDLSENRLESL 166
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 3/152 (1%)
Query: 34 EITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
++T +P LYT + L L N+I+ + P+ I L
Sbjct: 234 DLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSK 293
Query: 94 LVNLNLSYNPLNV--LIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
L L L+ N L+ L IG L LE F L+ +P+ + + +L N L
Sbjct: 294 LKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKNHLV 353
Query: 152 TIPEEMTSLAKLRWLTL-ENNQIETLPDTMDR 182
T+PE + L ++ L + EN + P DR
Sbjct: 354 TLPEAIHFLTEIEVLDVRENPNLVMPPKPADR 385
Score = 33.5 bits (73), Expect = 1.2
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Query: 147 GNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN+ K PE + ++ LRWL L + LP+ + + L H ++ +N L +
Sbjct: 17 GNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELS 76
Query: 205 KCKELMFLQLNSN 217
L + +N
Sbjct: 77 SLPSLRAIVARAN 89
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 70.1 bits (164), Expect = 1e-11
Identities = 43/136 (31%), Positives = 67/136 (49%), Gaps = 3/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE--IPKEIGKLTQLDT 142
P E+ L+ L +L++S+N L L E+ L L A LK +P +I KL L
Sbjct: 48 PEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSV 107
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPS 201
N+L P E+ + + L L +N I+T+P+ + +T L++ +L NRLE P
Sbjct: 108 LDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPP 167
Query: 202 SILKCKELMFLQLNSN 217
+ + L L LN N
Sbjct: 168 QMRRLVHLQTLVLNGN 183
Score = 64.1 bits (149), Expect = 8e-10
Identities = 37/100 (37%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 97 LNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
LNLS N L L I L KL+ + N ++ +P IGKLT L+ F A N L+ +P
Sbjct: 273 LNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVP 332
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
E + KLR L L N + TLP+ + +T + ++R N
Sbjct: 333 ESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 372
Score = 61.7 bits (143), Expect = 4e-09
Identities = 41/136 (30%), Positives = 69/136 (50%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
PT + L NL +++LS N L +PE + L L + + E+ I + ++T
Sbjct: 215 PTSLEGLSNLADVDLSCNDLT-RVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETL 273
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIET--LPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L ++P + L+KL+ L L +N+++ LP + ++T L NN LE P
Sbjct: 274 NLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPE 333
Query: 202 SILKCKELMFLQLNSN 217
S+ +C +L L LN N
Sbjct: 334 SLCRCPKLRKLVLNKN 349
Score = 57.2 bits (132), Expect = 9e-08
Identities = 55/198 (27%), Positives = 82/198 (41%), Gaps = 6/198 (3%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX- 84
S L L+ ++TE P L + L L N I P +
Sbjct: 106 SVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESL 165
Query: 85 PTEIGNLKNLVNLNLSYNPLNVL----IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQL 140
P ++ L +L L L+ NPL +P + L+ L R +P + L+ L
Sbjct: 166 PPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQ-SNLPTSLEGLSNL 224
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N+L +PE + +L LR L L +NQI L +D+ + NL N+L P
Sbjct: 225 ADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLP 284
Query: 201 SSILKCKELMFLQLNSNQ 218
S+I K +L L LNSN+
Sbjct: 285 SAICKLSKLKKLYLNSNK 302
Score = 55.2 bits (127), Expect = 3e-07
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + +L L L+ L L E+ L+KLE + L + E+ L L
Sbjct: 25 PENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIV 84
Query: 145 ARGNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
AR N LK +P+++ L L L L +NQ+ P ++ ++ NL +N ++ P+
Sbjct: 85 ARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQ 144
Query: 203 I-LKCKELMFLQLNSNQEHAL 222
+ + +L++L L+ N+ +L
Sbjct: 145 LFINLTDLLYLDLSENRLESL 165
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 3/152 (1%)
Query: 34 EITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
++T +P LYT + L L N+I+ + P+ I L
Sbjct: 233 DLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSK 292
Query: 94 LVNLNLSYNPLNV--LIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
L L L+ N L+ L IG L LE F L+ +P+ + + +L N L
Sbjct: 293 LKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKNHLV 352
Query: 152 TIPEEMTSLAKLRWLTL-ENNQIETLPDTMDR 182
T+PE + L ++ L + EN + P DR
Sbjct: 353 TLPEAIHFLTEIEVLDVRENPNLVMPPKPADR 384
Score = 33.5 bits (73), Expect = 1.2
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Query: 147 GNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN+ K PE + ++ LRWL L + LP+ + + L H ++ +N L +
Sbjct: 16 GNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELS 75
Query: 205 KCKELMFLQLNSN 217
L + +N
Sbjct: 76 SLPSLRAIVARAN 88
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 70.1 bits (164), Expect = 1e-11
Identities = 43/136 (31%), Positives = 67/136 (49%), Gaps = 3/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE--IPKEIGKLTQLDT 142
P E+ L+ L +L++S+N L L E+ L L A LK +P +I KL L
Sbjct: 49 PEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSV 108
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPS 201
N+L P E+ + + L L +N I+T+P+ + +T L++ +L NRLE P
Sbjct: 109 LDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPP 168
Query: 202 SILKCKELMFLQLNSN 217
+ + L L LN N
Sbjct: 169 QMRRLVHLQTLVLNGN 184
Score = 64.1 bits (149), Expect = 8e-10
Identities = 37/100 (37%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 97 LNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
LNLS N L L I L KL+ + N ++ +P IGKLT L+ F A N L+ +P
Sbjct: 274 LNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVP 333
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
E + KLR L L N + TLP+ + +T + ++R N
Sbjct: 334 ESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 373
Score = 61.7 bits (143), Expect = 4e-09
Identities = 41/136 (30%), Positives = 69/136 (50%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
PT + L NL +++LS N L +PE + L L + + E+ I + ++T
Sbjct: 216 PTSLEGLSNLADVDLSCNDLT-RVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETL 274
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIET--LPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L ++P + L+KL+ L L +N+++ LP + ++T L NN LE P
Sbjct: 275 NLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPE 334
Query: 202 SILKCKELMFLQLNSN 217
S+ +C +L L LN N
Sbjct: 335 SLCRCPKLRKLVLNKN 350
Score = 57.2 bits (132), Expect = 9e-08
Identities = 55/198 (27%), Positives = 82/198 (41%), Gaps = 6/198 (3%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX- 84
S L L+ ++TE P L + L L N I P +
Sbjct: 107 SVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESL 166
Query: 85 PTEIGNLKNLVNLNLSYNPLNVL----IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQL 140
P ++ L +L L L+ NPL +P + L+ L R +P + L+ L
Sbjct: 167 PPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQ-SNLPTSLEGLSNL 225
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N+L +PE + +L LR L L +NQI L +D+ + NL N+L P
Sbjct: 226 ADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLP 285
Query: 201 SSILKCKELMFLQLNSNQ 218
S+I K +L L LNSN+
Sbjct: 286 SAICKLSKLKKLYLNSNK 303
Score = 55.2 bits (127), Expect = 3e-07
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + +L L L+ L L E+ L+KLE + L + E+ L L
Sbjct: 26 PENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIV 85
Query: 145 ARGNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
AR N LK +P+++ L L L L +NQ+ P ++ ++ NL +N ++ P+
Sbjct: 86 ARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQ 145
Query: 203 I-LKCKELMFLQLNSNQEHAL 222
+ + +L++L L+ N+ +L
Sbjct: 146 LFINLTDLLYLDLSENRLESL 166
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 3/152 (1%)
Query: 34 EITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
++T +P LYT + L L N+I+ + P+ I L
Sbjct: 234 DLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSK 293
Query: 94 LVNLNLSYNPLNV--LIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
L L L+ N L+ L IG L LE F L+ +P+ + + +L N L
Sbjct: 294 LKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKNHLV 353
Query: 152 TIPEEMTSLAKLRWLTL-ENNQIETLPDTMDR 182
T+PE + L ++ L + EN + P DR
Sbjct: 354 TLPEAIHFLTEIEVLDVRENPNLVMPPKPADR 385
Score = 33.5 bits (73), Expect = 1.2
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Query: 147 GNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN+ K PE + ++ LRWL L + LP+ + + L H ++ +N L +
Sbjct: 17 GNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELS 76
Query: 205 KCKELMFLQLNSN 217
L + +N
Sbjct: 77 SLPSLRAIVARAN 89
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 70.1 bits (164), Expect = 1e-11
Identities = 43/136 (31%), Positives = 67/136 (49%), Gaps = 3/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE--IPKEIGKLTQLDT 142
P E+ L+ L +L++S+N L L E+ L L A LK +P +I KL L
Sbjct: 36 PEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSV 95
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPS 201
N+L P E+ + + L L +N I+T+P+ + +T L++ +L NRLE P
Sbjct: 96 LDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPP 155
Query: 202 SILKCKELMFLQLNSN 217
+ + L L LN N
Sbjct: 156 QMRRLVHLQTLVLNGN 171
Score = 64.1 bits (149), Expect = 8e-10
Identities = 37/100 (37%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 97 LNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
LNLS N L L I L KL+ + N ++ +P IGKLT L+ F A N L+ +P
Sbjct: 261 LNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVP 320
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
E + KLR L L N + TLP+ + +T + ++R N
Sbjct: 321 ESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 360
Score = 61.7 bits (143), Expect = 4e-09
Identities = 41/136 (30%), Positives = 69/136 (50%), Gaps = 4/136 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
PT + L NL +++LS N L +PE + L L + + E+ I + ++T
Sbjct: 203 PTSLEGLSNLADVDLSCNDLT-RVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETL 261
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIET--LPDTMDRMTALVHCNLRNNRLEQFPS 201
N+L ++P + L+KL+ L L +N+++ LP + ++T L NN LE P
Sbjct: 262 NLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPE 321
Query: 202 SILKCKELMFLQLNSN 217
S+ +C +L L LN N
Sbjct: 322 SLCRCPKLRKLVLNKN 337
Score = 57.2 bits (132), Expect = 9e-08
Identities = 55/198 (27%), Positives = 82/198 (41%), Gaps = 6/198 (3%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX- 84
S L L+ ++TE P L + L L N I P +
Sbjct: 94 SVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESL 153
Query: 85 PTEIGNLKNLVNLNLSYNPLNVL----IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQL 140
P ++ L +L L L+ NPL +P + L+ L R +P + L+ L
Sbjct: 154 PPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQ-SNLPTSLEGLSNL 212
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N+L +PE + +L LR L L +NQI L +D+ + NL N+L P
Sbjct: 213 ADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLP 272
Query: 201 SSILKCKELMFLQLNSNQ 218
S+I K +L L LNSN+
Sbjct: 273 SAICKLSKLKKLYLNSNK 290
Score = 55.2 bits (127), Expect = 3e-07
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + +L L L+ L L E+ L+KLE + L + E+ L L
Sbjct: 13 PENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIV 72
Query: 145 ARGNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
AR N LK +P+++ L L L L +NQ+ P ++ ++ NL +N ++ P+
Sbjct: 73 ARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQ 132
Query: 203 I-LKCKELMFLQLNSNQEHAL 222
+ + +L++L L+ N+ +L
Sbjct: 133 LFINLTDLLYLDLSENRLESL 153
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 3/152 (1%)
Query: 34 EITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 93
++T +P LYT + L L N+I+ + P+ I L
Sbjct: 221 DLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSK 280
Query: 94 LVNLNLSYNPLNV--LIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
L L L+ N L+ L IG L LE F L+ +P+ + + +L N L
Sbjct: 281 LKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKNHLV 340
Query: 152 TIPEEMTSLAKLRWLTL-ENNQIETLPDTMDR 182
T+PE + L ++ L + EN + P DR
Sbjct: 341 TLPEAIHFLTEIEVLDVRENPNLVMPPKPADR 372
Score = 33.5 bits (73), Expect = 1.2
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Query: 147 GNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN+ K PE + ++ LRWL L + LP+ + + L H ++ +N L +
Sbjct: 4 GNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELS 63
Query: 205 KCKELMFLQLNSN 217
L + +N
Sbjct: 64 SLPSLRAIVARAN 76
>BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein.
Length = 250
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/134 (30%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + + LV L LS N LN L PE+G L+ L+ + K +P+ + L QL
Sbjct: 18 PLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILY 77
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L +P E++ L LR L +E N + LPD + ++ L + +N L P +
Sbjct: 78 LGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 137
Query: 205 KCKELMFLQLNSNQ 218
+ +EL + L+ N+
Sbjct: 138 RLQELRTIWLSGNR 151
Score = 62.9 bits (146), Expect = 2e-09
Identities = 44/174 (25%), Positives = 73/174 (41%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
+ L+G ++ P + + E+ LYL N ++ P E P
Sbjct: 7 VDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQV 66
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+ LK L L L N L L E+ L+ L W L ++P + +L+ L T A
Sbjct: 67 VCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGS 126
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N L+ +P ++ L +LR + L N++ P + M L ++ N + FPS
Sbjct: 127 NALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFPS 180
Score = 58.4 bits (135), Expect = 4e-08
Identities = 38/133 (28%), Positives = 62/133 (46%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+G L+NL L L +N L + L++L + L ++P E+ L L T
Sbjct: 41 PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLW 100
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L +P+ + L+ L+ L +N + LP + R+ L L NRL FP+ +L
Sbjct: 101 IEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLL 160
Query: 205 KCKELMFLQLNSN 217
L + ++ N
Sbjct: 161 HMPFLEVIDVDWN 173
Score = 40.7 bits (91), Expect = 0.008
Identities = 24/91 (26%), Positives = 40/91 (43%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+ P + +L N L ++P E+ L L+ L L+ N + LP + + L
Sbjct: 14 LRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQL 73
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L NN+L PS + + L L + +N
Sbjct: 74 CILYLGNNKLCDLPSELSLLQNLRTLWIEAN 104
Score = 35.1 bits (77), Expect = 0.40
Identities = 19/72 (26%), Positives = 35/72 (48%)
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
G++L+ P + S +L L L +N + +LP + ++ L L N + P +
Sbjct: 11 GSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTL 70
Query: 207 KELMFLQLNSNQ 218
K+L L L +N+
Sbjct: 71 KQLCILYLGNNK 82
>BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein.
Length = 249
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/134 (30%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + + LV L LS N LN L PE+G L+ L+ + K +P+ + L QL
Sbjct: 17 PLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILY 76
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L +P E++ L LR L +E N + LPD + ++ L + +N L P +
Sbjct: 77 LGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 136
Query: 205 KCKELMFLQLNSNQ 218
+ +EL + L+ N+
Sbjct: 137 RLQELRTIWLSGNR 150
Score = 62.9 bits (146), Expect = 2e-09
Identities = 44/174 (25%), Positives = 73/174 (41%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
+ L+G ++ P + + E+ LYL N ++ P E P
Sbjct: 6 VDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQV 65
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+ LK L L L N L L E+ L+ L W L ++P + +L+ L T A
Sbjct: 66 VCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGS 125
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N L+ +P ++ L +LR + L N++ P + M L ++ N + FPS
Sbjct: 126 NALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFPS 179
Score = 58.4 bits (135), Expect = 4e-08
Identities = 38/133 (28%), Positives = 62/133 (46%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+G L+NL L L +N L + L++L + L ++P E+ L L T
Sbjct: 40 PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLW 99
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L +P+ + L+ L+ L +N + LP + R+ L L NRL FP+ +L
Sbjct: 100 IEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLL 159
Query: 205 KCKELMFLQLNSN 217
L + ++ N
Sbjct: 160 HMPFLEVIDVDWN 172
Score = 40.7 bits (91), Expect = 0.008
Identities = 24/91 (26%), Positives = 40/91 (43%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+ P + +L N L ++P E+ L L+ L L+ N + LP + + L
Sbjct: 13 LRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQL 72
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L NN+L PS + + L L + +N
Sbjct: 73 CILYLGNNKLCDLPSELSLLQNLRTLWIEAN 103
Score = 35.1 bits (77), Expect = 0.40
Identities = 19/72 (26%), Positives = 35/72 (48%)
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
G++L+ P + S +L L L +N + +LP + ++ L L N + P +
Sbjct: 10 GSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTL 69
Query: 207 KELMFLQLNSNQ 218
K+L L L +N+
Sbjct: 70 KQLCILYLGNNK 81
>BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat
containing 10 protein.
Length = 277
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/134 (30%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + + LV L LS N LN L PE+G L+ L+ + K +P+ + L QL
Sbjct: 45 PLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILY 104
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L +P E++ L LR L +E N + LPD + ++ L + +N L P +
Sbjct: 105 LGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 164
Query: 205 KCKELMFLQLNSNQ 218
+ +EL + L+ N+
Sbjct: 165 RLQELRTIWLSGNR 178
Score = 62.9 bits (146), Expect = 2e-09
Identities = 44/174 (25%), Positives = 73/174 (41%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
+ L+G ++ P + + E+ LYL N ++ P E P
Sbjct: 34 VDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQV 93
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+ LK L L L N L L E+ L+ L W L ++P + +L+ L T A
Sbjct: 94 VCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGS 153
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N L+ +P ++ L +LR + L N++ P + M L ++ N + FPS
Sbjct: 154 NALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFPS 207
Score = 58.4 bits (135), Expect = 4e-08
Identities = 38/133 (28%), Positives = 62/133 (46%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+G L+NL L L +N L + L++L + L ++P E+ L L T
Sbjct: 68 PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLW 127
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L +P+ + L+ L+ L +N + LP + R+ L L NRL FP+ +L
Sbjct: 128 IEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLL 187
Query: 205 KCKELMFLQLNSN 217
L + ++ N
Sbjct: 188 HMPFLEVIDVDWN 200
Score = 40.7 bits (91), Expect = 0.008
Identities = 24/91 (26%), Positives = 40/91 (43%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+ P + +L N L ++P E+ L L+ L L+ N + LP + + L
Sbjct: 41 LRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQL 100
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L NN+L PS + + L L + +N
Sbjct: 101 CILYLGNNKLCDLPSELSLLQNLRTLWIEAN 131
Score = 35.1 bits (77), Expect = 0.40
Identities = 19/72 (26%), Positives = 35/72 (48%)
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
G++L+ P + S +L L L +N + +LP + ++ L L N + P +
Sbjct: 38 GSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTL 97
Query: 207 KELMFLQLNSNQ 218
K+L L L +N+
Sbjct: 98 KQLCILYLGNNK 109
>AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens
cDNA FLJ41914 fis, clone PERIC2001228. ).
Length = 250
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/134 (30%), Positives = 68/134 (50%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + + LV L LS N LN L PE+G L+ L+ + K +P+ + L QL
Sbjct: 18 PLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILY 77
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N+L +P E++ L LR L +E N + LPD + ++ L + +N L P +
Sbjct: 78 LGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 137
Query: 205 KCKELMFLQLNSNQ 218
+ +EL + L+ N+
Sbjct: 138 RLQELRTIWLSGNR 151
Score = 62.9 bits (146), Expect = 2e-09
Identities = 44/174 (25%), Positives = 73/174 (41%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
+ L+G ++ P + + E+ LYL N ++ P E P
Sbjct: 7 VDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQV 66
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+ LK L L L N L L E+ L+ L W L ++P + +L+ L T A
Sbjct: 67 VCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGS 126
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N L+ +P ++ L +LR + L N++ P + M L ++ N + FPS
Sbjct: 127 NALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFPS 180
Score = 58.4 bits (135), Expect = 4e-08
Identities = 38/133 (28%), Positives = 62/133 (46%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+G L+NL L L +N L + L++L + L ++P E+ L L T
Sbjct: 41 PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLW 100
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
N L +P+ + L+ L+ L +N + LP + R+ L L NRL FP+ +L
Sbjct: 101 IEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLL 160
Query: 205 KCKELMFLQLNSN 217
L + ++ N
Sbjct: 161 HMPFLEVIDVDWN 173
Score = 40.7 bits (91), Expect = 0.008
Identities = 24/91 (26%), Positives = 40/91 (43%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+ P + +L N L ++P E+ L L+ L L+ N + LP + + L
Sbjct: 14 LRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQL 73
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L NN+L PS + + L L + +N
Sbjct: 74 CILYLGNNKLCDLPSELSLLQNLRTLWIEAN 104
Score = 35.1 bits (77), Expect = 0.40
Identities = 19/72 (26%), Positives = 35/72 (48%)
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
G++L+ P + S +L L L +N + +LP + ++ L L N + P +
Sbjct: 11 GSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTL 70
Query: 207 KELMFLQLNSNQ 218
K+L L L +N+
Sbjct: 71 KQLCILYLGNNK 82
>AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein.
Length = 1052
Score = 68.9 bits (161), Expect = 3e-11
Identities = 46/172 (26%), Positives = 72/172 (41%)
Query: 47 EVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNV 106
E+ L L N++ P + P + L L L++ +N L
Sbjct: 136 ELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTA 195
Query: 107 LIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWL 166
++ L LE + L+ +P++I L L G EL T+P LA L L
Sbjct: 196 FPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESL 255
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L+NN ++ LP + L NL +N E+FP+++L L L L+ NQ
Sbjct: 256 MLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQ 307
Score = 61.3 bits (142), Expect = 5e-09
Identities = 46/184 (25%), Positives = 74/184 (40%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+ +P L + L + N+++ FP + P +I L+ L
Sbjct: 170 LAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRAL 229
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
L LS L L +L LE+ + GL+ +P + L +L N + P
Sbjct: 230 KILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFP 289
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 214
+ LA L L L NQ+ ++P + + L+ L NNR+ P SI++ L L L
Sbjct: 290 AALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVL 349
Query: 215 NSNQ 218
NQ
Sbjct: 350 QGNQ 353
Score = 58.4 bits (135), Expect = 4e-08
Identities = 40/173 (23%), Positives = 74/173 (42%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L ++ ++T P L + +E L + N++ P + P
Sbjct: 186 LDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAG 245
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
L +L +L L N L L + L++L+ + +E P + L L+
Sbjct: 246 FCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSR 305
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N+L ++P ++ L +L L L+NN+I LPD++ +T L L+ N++ P
Sbjct: 306 NQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLP 358
Score = 58.0 bits (134), Expect = 5e-08
Identities = 38/135 (28%), Positives = 62/135 (45%)
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
+ L+ L LNLS+N L L ++G L LE + L +P + L++L T
Sbjct: 131 VSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDH 190
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N+L P ++ L L L + +N++ LP+ + + AL L L P+ +
Sbjct: 191 NQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELA 250
Query: 208 ELMFLQLNSNQEHAL 222
L L L++N AL
Sbjct: 251 SLESLMLDNNGLQAL 265
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/119 (28%), Positives = 55/119 (46%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L+ L LNLS N + L LE + +R L +P I L +L T
Sbjct: 266 PAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLW 325
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ +P+ + L L L L+ NQI LPD +++ + +++N L Q P +
Sbjct: 326 LDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPPYEV 384
Score = 44.8 bits (101), Expect = 5e-04
Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 3/132 (2%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARG 147
NL ++ LNL N L + +G L L R +P + +L L
Sbjct: 61 NLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSH 120
Query: 148 NELKTIPEEMTS-LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
N L + E+ S L +LR L L +NQ+ LP + + L ++ NRL P S+
Sbjct: 121 NRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCL 180
Query: 207 KELMFLQLNSNQ 218
L L ++ NQ
Sbjct: 181 SRLRTLDVDHNQ 192
>D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein.
Length = 823
Score = 68.1 bits (159), Expect = 5e-11
Identities = 47/179 (26%), Positives = 83/179 (46%), Gaps = 7/179 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI---GLKEIPKEIGKLTQLD 141
P I +L NL L+L N L + EI + L+ C ++ + IP +IG L+ L+
Sbjct: 621 PHSIFSLNNLHELDLRENNLKT-VEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLE 679
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N ++ +P ++ KL +L L N + +P+ + ++ L + + NN +E P
Sbjct: 680 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPD 739
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMPSTSRVYGAQALALN 259
+ +CK+L L L N L + E + T + G+ +P + G Q+L N
Sbjct: 740 GLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP--PELEGCQSLKRN 796
Score = 50.0 bits (114), Expect = 1e-05
Identities = 57/228 (25%), Positives = 97/228 (42%), Gaps = 18/228 (7%)
Query: 5 LKFIRENHILALIEQ-AIAKKKSRLSLNGFEITE---IPGLLYTCLEVEHLYLH----KN 56
LK +R H +++ A+A + L + + TE IP ++ ++ LYL
Sbjct: 485 LKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPE 544
Query: 57 KISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNL-KNLVNLNLSY--NPLNVL--IPEI 111
++S +E P + +L +L L+L + L VL + ++
Sbjct: 545 QLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKM 604
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE--EMTSLAKLRWLTLE 169
+L+ LE C+ L+ IP I L L R N LKT+ E L L L L
Sbjct: 605 VNLKSLELISCD---LERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLW 661
Query: 170 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+N I +P + ++ L +L +N +E P + C +L +L L+ N
Sbjct: 662 HNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYN 709
Score = 37.9 bits (84), Expect = 0.057
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 25/153 (16%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LSL+ I +P L+ C ++ +L L N ++ P
Sbjct: 680 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIP-----------------------E 716
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
EI L NL ++ N + +L + +KL+ + L + +G+L+ L
Sbjct: 717 EIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELI 776
Query: 147 GNELKTIPEEMTSLAKLR--WLTLENNQIETLP 177
GN L+T+P E+ L+ L +E N + TLP
Sbjct: 777 GNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 809
>BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein.
Length = 803
Score = 68.1 bits (159), Expect = 5e-11
Identities = 47/179 (26%), Positives = 83/179 (46%), Gaps = 7/179 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI---GLKEIPKEIGKLTQLD 141
P I +L NL L+L N L + EI + L+ C ++ + IP +IG L+ L+
Sbjct: 601 PHSIFSLNNLHELDLRENNLKT-VEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLE 659
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N ++ +P ++ KL +L L N + +P+ + ++ L + + NN +E P
Sbjct: 660 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPD 719
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMPSTSRVYGAQALALN 259
+ +CK+L L L N L + E + T + G+ +P + G Q+L N
Sbjct: 720 GLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP--PELEGCQSLKRN 776
Score = 50.0 bits (114), Expect = 1e-05
Identities = 57/228 (25%), Positives = 97/228 (42%), Gaps = 18/228 (7%)
Query: 5 LKFIRENHILALIEQ-AIAKKKSRLSLNGFEITE---IPGLLYTCLEVEHLYLH----KN 56
LK +R H +++ A+A + L + + TE IP ++ ++ LYL
Sbjct: 465 LKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPE 524
Query: 57 KISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNL-KNLVNLNLSY--NPLNVL--IPEI 111
++S +E P + +L +L L+L + L VL + ++
Sbjct: 525 QLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKM 584
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE--EMTSLAKLRWLTLE 169
+L+ LE C+ L+ IP I L L R N LKT+ E L L L L
Sbjct: 585 VNLKSLELISCD---LERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLW 641
Query: 170 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+N I +P + ++ L +L +N +E P + C +L +L L+ N
Sbjct: 642 HNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYN 689
Score = 37.9 bits (84), Expect = 0.057
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 25/153 (16%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LSL+ I +P L+ C ++ +L L N ++ P
Sbjct: 660 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIP-----------------------E 696
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
EI L NL ++ N + +L + +KL+ + L + +G+L+ L
Sbjct: 697 EIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELI 756
Query: 147 GNELKTIPEEMTSLAKLR--WLTLENNQIETLP 177
GN L+T+P E+ L+ L +E N + TLP
Sbjct: 757 GNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 789
>BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat
containing 8 family, member B protein.
Length = 803
Score = 68.1 bits (159), Expect = 5e-11
Identities = 47/179 (26%), Positives = 83/179 (46%), Gaps = 7/179 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI---GLKEIPKEIGKLTQLD 141
P I +L NL L+L N L + EI + L+ C ++ + IP +IG L+ L+
Sbjct: 601 PHSIFSLNNLHELDLRENNLKT-VEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLE 659
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N ++ +P ++ KL +L L N + +P+ + ++ L + + NN +E P
Sbjct: 660 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPD 719
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMPSTSRVYGAQALALN 259
+ +CK+L L L N L + E + T + G+ +P + G Q+L N
Sbjct: 720 GLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP--PELEGCQSLKRN 776
Score = 50.0 bits (114), Expect = 1e-05
Identities = 57/228 (25%), Positives = 97/228 (42%), Gaps = 18/228 (7%)
Query: 5 LKFIRENHILALIEQ-AIAKKKSRLSLNGFEITE---IPGLLYTCLEVEHLYLH----KN 56
LK +R H +++ A+A + L + + TE IP ++ ++ LYL
Sbjct: 465 LKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPE 524
Query: 57 KISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNL-KNLVNLNLSY--NPLNVL--IPEI 111
++S +E P + +L +L L+L + L VL + ++
Sbjct: 525 QLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKM 584
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE--EMTSLAKLRWLTLE 169
+L+ LE C+ L+ IP I L L R N LKT+ E L L L L
Sbjct: 585 VNLKSLELISCD---LERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLW 641
Query: 170 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+N I +P + ++ L +L +N +E P + C +L +L L+ N
Sbjct: 642 HNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYN 689
Score = 37.9 bits (84), Expect = 0.057
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 25/153 (16%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LSL+ I +P L+ C ++ +L L N ++ P
Sbjct: 660 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIP-----------------------E 696
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
EI L NL ++ N + +L + +KL+ + L + +G+L+ L
Sbjct: 697 EIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELI 756
Query: 147 GNELKTIPEEMTSLAKLR--WLTLENNQIETLP 177
GN L+T+P E+ L+ L +E N + TLP
Sbjct: 757 GNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 789
>AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leucine
repeat-rich protein protein.
Length = 803
Score = 68.1 bits (159), Expect = 5e-11
Identities = 47/179 (26%), Positives = 83/179 (46%), Gaps = 7/179 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI---GLKEIPKEIGKLTQLD 141
P I +L NL L+L N L + EI + L+ C ++ + IP +IG L+ L+
Sbjct: 601 PHSIFSLNNLHELDLRENNLKT-VEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLE 659
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
N ++ +P ++ KL +L L N + +P+ + ++ L + + NN +E P
Sbjct: 660 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPD 719
Query: 202 SILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMPSTSRVYGAQALALN 259
+ +CK+L L L N L + E + T + G+ +P + G Q+L N
Sbjct: 720 GLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP--PELEGCQSLKRN 776
Score = 50.0 bits (114), Expect = 1e-05
Identities = 57/228 (25%), Positives = 97/228 (42%), Gaps = 18/228 (7%)
Query: 5 LKFIRENHILALIEQ-AIAKKKSRLSLNGFEITE---IPGLLYTCLEVEHLYLH----KN 56
LK +R H +++ A+A + L + + TE IP ++ ++ LYL
Sbjct: 465 LKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPE 524
Query: 57 KISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNL-KNLVNLNLSY--NPLNVL--IPEI 111
++S +E P + +L +L L+L + L VL + ++
Sbjct: 525 QLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKM 584
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE--EMTSLAKLRWLTLE 169
+L+ LE C+ L+ IP I L L R N LKT+ E L L L L
Sbjct: 585 VNLKSLELISCD---LERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLW 641
Query: 170 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+N I +P + ++ L +L +N +E P + C +L +L L+ N
Sbjct: 642 HNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYN 689
Score = 37.9 bits (84), Expect = 0.057
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 25/153 (16%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LSL+ I +P L+ C ++ +L L N ++ P
Sbjct: 660 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIP-----------------------E 696
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
EI L NL ++ N + +L + +KL+ + L + +G+L+ L
Sbjct: 697 EIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELI 756
Query: 147 GNELKTIPEEMTSLAKLR--WLTLENNQIETLP 177
GN L+T+P E+ L+ L +E N + TLP
Sbjct: 757 GNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 789
>BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein.
Length = 280
Score = 66.5 bits (155), Expect = 1e-10
Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Query: 44 TCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNP 103
T + L L NK+++ P PT+I +L+ L +LNL N
Sbjct: 41 TLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR 100
Query: 104 LNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLA 161
LN L G L LE N + +P LT L N+ + +P ++ L
Sbjct: 101 LNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLT 160
Query: 162 KLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 161 KLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 202
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Query: 1 MSAILKFIRENHILALIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKI 58
+S I + + ++ L ++ IA+ K+ LN F +I E+P + + +++HL L N++
Sbjct: 42 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 101
Query: 59 SVFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK 116
+ P P L L L LS N +L P+IG L K
Sbjct: 102 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 161
Query: 117 LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSL 160
L+ L +PKEIG+LTQL +GN L +P E+ +L
Sbjct: 162 LQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 205
Score = 60.5 bits (140), Expect = 9e-09
Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 42 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 99
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 100 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 159
Query: 207 KELMFLQLNSNQEHALIKYTDEAT 230
+L L L N +L K E T
Sbjct: 160 TKLQILSLRDNDLISLPKEIGELT 183
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
++L L+ ++T +P + +E L N+I P + P
Sbjct: 46 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 105
Query: 86 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 106 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 165
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 166 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 205
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 119 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 178
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 179 IGELTQLKELHIQGNRLTVLPPELGNLD 206
>AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein.
Length = 802
Score = 66.1 bits (154), Expect = 2e-10
Identities = 50/180 (27%), Positives = 82/180 (45%), Gaps = 10/180 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIG--DLEKLEAF--WCNRIGLKEIPKEIGKLTQL 140
P I +L NL L+L N L + EI L+ L W N I IP +IG L+ L
Sbjct: 601 PHSIFSLNNLHELDLRENNLKT-VEEISFQHLQNLSCLKLWHNNIAY--IPAQIGALSNL 657
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
+ N ++ +P ++ KL +L L N + +P+ + ++ L + + NN +E P
Sbjct: 658 EQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLP 717
Query: 201 SSILKCKELMFLQLNSNQEHALIKYTDEATTQTS-DSNGSLASAMPSTSRVYGAQALALN 259
+ +CK+L L L N L + E + T + G+ +P + G Q+L N
Sbjct: 718 DGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP--PELEGCQSLKRN 775
Score = 60.5 bits (140), Expect = 9e-09
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 1/183 (0%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L L ++ IP +++ + L L +N + +V + P
Sbjct: 590 LELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEISFQHLQNLSCLKLWHNNIAYIPA 649
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
+IG L NL L+L +N + L ++ KL + L IP+EI L+ L F
Sbjct: 650 QIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVT 709
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
N ++ +P+ + KL+ L L N + L + ++ L H L N LE P + C
Sbjct: 710 NNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGC 769
Query: 207 KEL 209
+ L
Sbjct: 770 QSL 772
Score = 37.9 bits (84), Expect = 0.057
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 25/153 (16%)
Query: 27 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
+LSL+ I +P L+ C ++ +L L N ++ P
Sbjct: 659 QLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIP-----------------------E 695
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
EI L NL ++ N + +L + +KL+ + L + +G+L+ L
Sbjct: 696 EIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELI 755
Query: 147 GNELKTIPEEMTSLAKLR--WLTLENNQIETLP 177
GN L+T+P E+ L+ L +E N + TLP
Sbjct: 756 GNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 788
>BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine rich
repeat protein phosphatase-like protein.
Length = 1323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/183 (26%), Positives = 83/183 (45%), Gaps = 2/183 (1%)
Query: 42 LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 101
LY +++ L L NK+ +FP+ P++IGNL NL L L
Sbjct: 295 LYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDG 354
Query: 102 NPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSL 160
N L L E+G+L++L + + +IP+ KLT LD GN L+ + + +
Sbjct: 355 NFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRM 414
Query: 161 AKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQE 219
++ + L N ++T+ + ++ + H +LR+NRL S L E + N +E
Sbjct: 415 NHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRE 474
Query: 220 HAL 222
L
Sbjct: 475 LTL 477
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/134 (30%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
Query: 94 LVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L LNLS+N L +L+ EI L +L CN G ++P +IG L L T GN L
Sbjct: 301 LKGLNLSHNKLGLFPILLCEISTLTELNLS-CN--GFHDLPSQIGNLLNLQTLCLDGNFL 357
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL-KCKEL 209
T+PEE+ +L +L L + N +P+ +++T L + N LE +L + +
Sbjct: 358 TTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 417
Query: 210 MFLQLNSNQEHALI 223
+ L N ++
Sbjct: 418 KHVDLRMNHLKTMV 431
Score = 49.6 bits (113), Expect = 2e-05
Identities = 58/225 (25%), Positives = 89/225 (39%), Gaps = 9/225 (4%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
AKK L ++ +TE+P + + L + L L N + P
Sbjct: 524 AKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALT 583
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPE-IGD--LEKLEAFWCNRIGLKE--IPKEIGK 136
T NL LN S N L L G+ L L+ + L + IP +G
Sbjct: 584 RLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGH 643
Query: 137 LTQLDTFGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
L L N+L+T P ++ L +L L L N+++T+P T+ L +N
Sbjct: 644 L-HLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNN 702
Query: 196 LEQFPSSILKCKELMFLQLNSNQ-EHALIKYTDEATTQTSDSNGS 239
+ FP IL+ ++ F+ L+ N LI AT Q D G+
Sbjct: 703 ISIFP-EILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGN 746
Score = 39.5 bits (88), Expect = 0.019
Identities = 46/181 (25%), Positives = 71/181 (39%), Gaps = 7/181 (3%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
GN K++ +++L N L L ++ L LE C R L+E+ L L R
Sbjct: 437 GN-KHITHVDLRDNRLTDL--DLSSLCSLEQLHCGRNQLRELTLSGFSLRTLYASSNRLT 493
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 208
+ P + SL L +L L N +E +PD + ++ N L + P IL
Sbjct: 494 AVNVYP--VPSL--LTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLS 549
Query: 209 LMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALALNATALRLPAA 268
L L L N L + + D + + +P T LNA+A L +
Sbjct: 550 LRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESL 609
Query: 269 P 269
P
Sbjct: 610 P 610
Score = 37.5 bits (83), Expect = 0.075
Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 133 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 192
++ KL QL+ GN+LKTIP + + +L L +N I P+ + ++ + +L
Sbjct: 663 KLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPEIL-QLPQIQFVDLS 721
Query: 193 NNRLEQ--FPSSILKCKELMFLQLNSN--QEHALIKYTDEATTQTSD 235
N L + P ++ + + L N+N EH + TT D
Sbjct: 722 CNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDIFSHITTLKID 768
Score = 31.9 bits (69), Expect = 3.7
Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 150 LKTIPEEMTSLAKLRWLTLENN--QIETLP--DTMDRMTALVHCNLRNNRLEQFPSSILK 205
L+ +PE + + +L L +N Q+E DT+ + + L NL +N+L FP + +
Sbjct: 261 LEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCE 320
Query: 206 CKELMFLQLNSNQEHAL-IKYTDEATTQTSDSNGSLASAMP 245
L L L+ N H L + + QT +G+ + +P
Sbjct: 321 ISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLP 361
>BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein.
Length = 723
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/183 (26%), Positives = 83/183 (45%), Gaps = 2/183 (1%)
Query: 42 LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 101
LY +++ L L NK+ +FP+ P++IGNL NL L L
Sbjct: 33 LYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDG 92
Query: 102 NPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSL 160
N L L E+G+L++L + + +IP+ KLT LD GN L+ + + +
Sbjct: 93 NFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRM 152
Query: 161 AKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQE 219
++ + L N ++T+ + ++ + H +LR+NRL S L E + N +E
Sbjct: 153 NHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRE 212
Query: 220 HAL 222
L
Sbjct: 213 LTL 215
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/134 (30%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
Query: 94 LVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L LNLS+N L +L+ EI L +L CN G ++P +IG L L T GN L
Sbjct: 39 LKGLNLSHNKLGLFPILLCEISTLTELNLS-CN--GFHDLPSQIGNLLNLQTLCLDGNFL 95
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL-KCKEL 209
T+PEE+ +L +L L + N +P+ +++T L + N LE +L + +
Sbjct: 96 TTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 155
Query: 210 MFLQLNSNQEHALI 223
+ L N ++
Sbjct: 156 KHVDLRMNHLKTMV 169
Score = 49.6 bits (113), Expect = 2e-05
Identities = 58/225 (25%), Positives = 89/225 (39%), Gaps = 9/225 (4%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
AKK L ++ +TE+P + + L + L L N + P
Sbjct: 262 AKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALT 321
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPE-IGD--LEKLEAFWCNRIGLKE--IPKEIGK 136
T NL LN S N L L G+ L L+ + L + IP +G
Sbjct: 322 RLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGH 381
Query: 137 LTQLDTFGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 195
L L N+L+T P ++ L +L L L N+++T+P T+ L +N
Sbjct: 382 L-HLRILRLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNN 440
Query: 196 LEQFPSSILKCKELMFLQLNSNQ-EHALIKYTDEATTQTSDSNGS 239
+ FP IL+ ++ F+ L+ N LI AT Q D G+
Sbjct: 441 ISIFP-EILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGN 484
Score = 39.5 bits (88), Expect = 0.019
Identities = 46/181 (25%), Positives = 71/181 (39%), Gaps = 7/181 (3%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
GN K++ +++L N L L ++ L LE C R L+E+ L L R
Sbjct: 175 GN-KHITHVDLRDNRLTDL--DLSSLCSLEQLHCGRNQLRELTLSGFSLRTLYASSNRLT 231
Query: 149 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 208
+ P + SL L +L L N +E +PD + ++ N L + P IL
Sbjct: 232 AVNVYP--VPSL--LTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLS 287
Query: 209 LMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALALNATALRLPAA 268
L L L N L + + D + + +P T LNA+A L +
Sbjct: 288 LRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESL 347
Query: 269 P 269
P
Sbjct: 348 P 348
Score = 37.5 bits (83), Expect = 0.075
Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 133 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 192
++ KL QL+ GN+LKTIP + + +L L +N I P+ + ++ + +L
Sbjct: 401 KLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPEIL-QLPQIQFVDLS 459
Query: 193 NNRLEQ--FPSSILKCKELMFLQLNSN--QEHALIKYTDEATTQTSD 235
N L + P ++ + + L N+N EH + TT D
Sbjct: 460 CNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDIFSHITTLKID 506
>AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein.
Length = 1258
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/183 (26%), Positives = 83/183 (45%), Gaps = 2/183 (1%)
Query: 42 LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 101
LY +++ L L NK+ +FP+ P++IGNL NL L L
Sbjct: 297 LYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDG 356
Query: 102 NPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSL 160
N L L E+G+L++L + + +IP+ KLT LD GN L+ + + +
Sbjct: 357 NFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRM 416
Query: 161 AKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQE 219
++ + L N ++T+ + ++ + H +LR+NRL S L E + N +E
Sbjct: 417 NHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRE 476
Query: 220 HAL 222
L
Sbjct: 477 LTL 479
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/134 (30%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
Query: 94 LVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L LNLS+N L +L+ EI L +L CN G ++P +IG L L T GN L
Sbjct: 303 LKGLNLSHNKLGLFPILLCEISTLTELNLS-CN--GFHDLPSQIGNLLNLQTLCLDGNFL 359
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL-KCKEL 209
T+PEE+ +L +L L + N +P+ +++T L + N LE +L + +
Sbjct: 360 TTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 419
Query: 210 MFLQLNSNQEHALI 223
+ L N ++
Sbjct: 420 KHVDLRMNHLKTMV 433
Score = 43.6 bits (98), Expect = 0.001
Identities = 48/220 (21%), Positives = 92/220 (41%), Gaps = 17/220 (7%)
Query: 8 IRENHILALIEQAIAKKK--SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEX 65
+R NH+ ++ + + K + + L +T++ L + +E L+ +N++ +
Sbjct: 424 LRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLD--LSSLCSLEQLHCGRNQLRELTLSG 481
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P + +L L L+LS N L + + +K+E +
Sbjct: 482 FSLRTLYASSNRLTAVNVYP--VPSL--LTFLDLSRNLLECVPDWACEAKKIEVLDVSYN 537
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM----- 180
L E+P I L N ++ +P + + L L L++N + LPDT+
Sbjct: 538 LLTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHIP-LEVLDLQHNALTRLPDTLFSKAL 596
Query: 181 ---DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+++ L NL N+L+ P++I CK L L +SN
Sbjct: 597 NKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSN 636
Score = 37.5 bits (83), Expect = 0.075
Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 133 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 192
++ KL QL+ GN+LKTIP + + +L L +N I P+ + ++ + +L
Sbjct: 598 KLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPEIL-QLPQIQFVDLS 656
Query: 193 NNRLEQ--FPSSILKCKELMFLQLNSN--QEHALIKYTDEATTQTSD 235
N L + P ++ + + L N+N EH + TT D
Sbjct: 657 CNDLTEILIPEALPATLQDLDLTGNTNLVLEHKTLDIFSHITTLKID 703
Score = 31.9 bits (69), Expect = 3.7
Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 150 LKTIPEEMTSLAKLRWLTLENN--QIETLP--DTMDRMTALVHCNLRNNRLEQFPSSILK 205
L+ +PE + + +L L +N Q+E DT+ + + L NL +N+L FP + +
Sbjct: 263 LEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCE 322
Query: 206 CKELMFLQLNSNQEHAL-IKYTDEATTQTSDSNGSLASAMP 245
L L L+ N H L + + QT +G+ + +P
Sbjct: 323 ISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLP 363
Score = 31.5 bits (68), Expect = 4.9
Identities = 13/35 (37%), Positives = 20/35 (57%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFP 62
L+L+G ++ IP + C + L H N IS+FP
Sbjct: 608 LNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFP 642
>AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ20331 fis, clone HEP10410. ).
Length = 384
Score = 64.5 bits (150), Expect = 6e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 85 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 223 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 282
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 202
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 283 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 342
Query: 203 ILKCKELMFLQLNSN 217
+ C L L L+ N
Sbjct: 343 LGNCVNLRTLLLDGN 357
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 6/147 (4%)
Query: 127 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 219 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 278
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL----IKYTDEATTQTSDSNGSLA 241
L NL NR + P + + L + +++NQ ++ +K + TT +N L
Sbjct: 279 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNN-DLL 337
Query: 242 SAMPSTSRVYGAQALALNATALRLPAA 268
P + L L+ R+P A
Sbjct: 338 QIPPELGNCVNLRTLLLDGNPFRVPRA 364
Score = 52.0 bits (119), Expect = 3e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 2/110 (1%)
Query: 114 LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI 173
+++L+ CN L+ IP E+ + L+ R N+L+ +P E S + L+ L + NQI
Sbjct: 1 MKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQI 59
Query: 174 ETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
E L + + + +++ +LR+N+L+ P I+ + L L L++N +L
Sbjct: 60 EMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSL 109
Score = 44.4 bits (100), Expect = 7e-04
Identities = 43/167 (25%), Positives = 75/167 (44%), Gaps = 10/167 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTF 143
P E+ +++L L L N L L PE L+ ++ + E + L +
Sbjct: 18 PPELAGMESLELLYLRRNKLRFL-PEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 76
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
R N+LK++P+E+ L L L L NN I +LP ++ + +L+ LE P
Sbjct: 77 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL------HLKFLALEGNPLRT 130
Query: 204 LKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSRV 250
++ +E++ ++ D+ +Q S+S A +PS SRV
Sbjct: 131 IR-REIISKGTQEVLKYLRSTIKDDGPSQ-SESATETAMTLPSESRV 175
Score = 37.9 bits (84), Expect = 0.057
Identities = 34/137 (24%), Positives = 52/137 (37%), Gaps = 1/137 (0%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXX 82
K+ L N + IP L +E LYL +NK+ P
Sbjct: 2 KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEM 61
Query: 83 XXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ +L +++ L+L N L + EI L LE + + +P +G L L
Sbjct: 62 LEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKF 120
Query: 143 FGARGNELKTIPEEMTS 159
GN L+TI E+ S
Sbjct: 121 LALEGNPLRTIRREIIS 137
Score = 33.5 bits (73), Expect = 1.2
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 8 IRENHILAL---IEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SVFPV 63
+R N + +L +E + + LS N F++ +P +LY +E + + N++ SV P
Sbjct: 261 LRNNFLNSLPEEMESLVRLQTINLSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQ 318
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNV 106
+ P E+GN NL L L NP V
Sbjct: 319 KMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRV 361
>BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat
containing 18 protein.
Length = 261
Score = 63.7 bits (148), Expect = 1e-09
Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+++G+ PK I +L+ +D N ++ IP+ ++ LRWL L +N I+ LP+++ +
Sbjct: 35 SKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQ 94
Query: 183 MTALVHCNLRNNRLEQ--FPSSILKCKELMFLQLNSN 217
MT+L++ N+ NNRL P + + K + + L N
Sbjct: 95 MTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLN 131
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 2/149 (1%)
Query: 25 KSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX 84
K RL L+ IT P + +++ L L +N I P
Sbjct: 29 KKRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKL 88
Query: 85 PTEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P IG + +L+ LN+S N L N L E+ L+ + A L + +G L +L
Sbjct: 89 PESIGQMTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVSTTLGALKELHE 148
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENN 171
G N L IP ++ L KL+ L ++ N
Sbjct: 149 VGLHDNLLNNIPVSISKLPKLKKLNIKRN 177
Score = 38.7 bits (86), Expect = 0.032
Identities = 18/69 (26%), Positives = 39/69 (56%)
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
+ T P+ + L+ + L L N I +PD++ + L +L +N +++ P SI + L
Sbjct: 39 ITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSL 98
Query: 210 MFLQLNSNQ 218
++L +++N+
Sbjct: 99 LYLNVSNNR 107
Score = 31.5 bits (68), Expect = 4.9
Identities = 17/52 (32%), Positives = 27/52 (51%)
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L L I T P + R++ + +L N + + P SI K + L +L L+SN
Sbjct: 32 LDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSN 83
>AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein.
Length = 255
Score = 63.7 bits (148), Expect = 1e-09
Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+++G+ PK I +L+ +D N ++ IP+ ++ LRWL L +N I+ LP+++ +
Sbjct: 35 SKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQ 94
Query: 183 MTALVHCNLRNNRLEQ--FPSSILKCKELMFLQLNSN 217
MT+L++ N+ NNRL P + + K + + L N
Sbjct: 95 MTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLN 131
Score = 40.7 bits (91), Expect = 0.008
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWC--NRIGLKEIPKEIGKLTQLDT 142
P I +NL L+L N ++ L IG + L NR+ +P E+ +L +
Sbjct: 66 PDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQLKNIRA 125
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
N L ++P + +L +L + L +N + +P ++ ++ L N++ N
Sbjct: 126 VNLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRN 177
Score = 38.7 bits (86), Expect = 0.032
Identities = 18/69 (26%), Positives = 39/69 (56%)
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
+ T P+ + L+ + L L N I +PD++ + L +L +N +++ P SI + L
Sbjct: 39 ITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSL 98
Query: 210 MFLQLNSNQ 218
++L +++N+
Sbjct: 99 LYLNVSNNR 107
Score = 31.5 bits (68), Expect = 4.9
Identities = 17/52 (32%), Positives = 27/52 (51%)
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L L I T P + R++ + +L N + + P SI K + L +L L+SN
Sbjct: 32 LDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSN 83
>AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens
cDNA FLJ11834 fis, clone HEMBA1006583, weakly similar to
Drosophila melanogaster Scribble (scrib) mRNA. ).
Length = 197
Score = 63.3 bits (147), Expect = 1e-09
Identities = 40/138 (28%), Positives = 63/138 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
GN L +PE L L L++ + +++LP+ + + L LR N L P S+
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLT 171
Query: 205 KCKELMFLQLNSNQEHAL 222
+ + L L L +N+ + L
Sbjct: 172 QLRRLEELDLGNNEIYNL 189
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/155 (27%), Positives = 65/155 (41%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+ L L+ ++ E+P + +++ L L N+I P E
Sbjct: 35 ARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P I K L + S NPL L +L+ L N I L+ +P+ IG L L
Sbjct: 95 PEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLA 154
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETL 176
+ R N L +P+ +T L +L L L NN+I L
Sbjct: 155 SLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNL 189
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 3/137 (2%)
Query: 130 IPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVH 188
+P+EI + + L+ N+L+ +PE+ L KLR L L +N+I+ LP + LV
Sbjct: 27 VPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE 86
Query: 189 CNLRNNRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQT--SDSNGSLASAMPS 246
++ N + + P SI CK L + N L + E T S ++ SL S +
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 247 TSRVYGAQALALNATAL 263
+Y +L L L
Sbjct: 147 IGNLYNLASLELRENLL 163
Score = 48.4 bits (110), Expect = 4e-05
Identities = 24/89 (26%), Positives = 47/89 (52%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+E+P++ +L +L G NE++ +P E+ + +L L + N+I +P+++ AL
Sbjct: 48 LRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKAL 107
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ N L + P S + + L L +N
Sbjct: 108 QVADFSGNPLTRLPESFPELQNLTCLSVN 136
Score = 47.6 bits (108), Expect = 7e-05
Identities = 35/141 (24%), Positives = 59/141 (41%), Gaps = 4/141 (2%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
IPE ++ L+ N + LP++ + L ++ + L+ P +I L
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLAS 155
Query: 212 LQLNSNQEHALIKYTDEATTQ 232
L+L N L+ Y ++ TQ
Sbjct: 156 LELREN----LLTYLPDSLTQ 172
>BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein.
Length = 403
Score = 62.9 bits (146), Expect = 2e-09
Identities = 40/126 (31%), Positives = 62/126 (49%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
++L LNLS N + + +L L+ L+ IP EI L L+ GN +K
Sbjct: 152 RSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIK 211
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 211
IP E+ +L L +L L +N+I+++P + ++ +L +L NN L P IL L
Sbjct: 212 EIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEE 271
Query: 212 LQLNSN 217
L L N
Sbjct: 272 LSLRGN 277
Score = 62.9 bits (146), Expect = 2e-09
Identities = 37/112 (33%), Positives = 59/112 (52%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L+ L L+L N L + EI +L+ LE + +KEIP E+G L L+
Sbjct: 168 PASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLNYLV 227
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
N++++IP +++ L LR L+L NN + LP + + L +LR N L
Sbjct: 228 LCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPL 279
Score = 48.8 bits (111), Expect = 3e-05
Identities = 34/135 (25%), Positives = 55/135 (40%)
Query: 16 LIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXX 75
L + + + L+L+G E+P L ++ L L N++ P E
Sbjct: 145 LAQSPLCRSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLY 204
Query: 76 XXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG 135
P E+GNL +L L L N + + P++ L L + + L +P+EI
Sbjct: 205 LGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREIL 264
Query: 136 KLTQLDTFGARGNEL 150
L L+ RGN L
Sbjct: 265 NLIHLEELSLRGNPL 279
Score = 44.8 bits (101), Expect = 5e-04
Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 7/141 (4%)
Query: 85 PTEIGN-LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWC--NRIG-LKEIPKEIGK---L 137
P +G+ +L L++S N L L PE+ L L NR+G +PK + +
Sbjct: 92 PRALGSGFPHLQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGPSALPKGLAQSPLC 151
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
L GN + +P + L L+ L+L NQ++++P ++ + +L L N ++
Sbjct: 152 RSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIK 211
Query: 198 QFPSSILKCKELMFLQLNSNQ 218
+ P + L +L L N+
Sbjct: 212 EIPPELGNLPSLNYLVLCDNK 232
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/79 (32%), Positives = 31/79 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L G I EIP L + +L L NKI P + P E
Sbjct: 203 LYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPRE 262
Query: 88 IGNLKNLVNLNLSYNPLNV 106
I NL +L L+L NPL V
Sbjct: 263 ILNLIHLEELSLRGNPLVV 281
>BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 62.9 bits (146), Expect = 2e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 210 MFLQ 213
LQ
Sbjct: 199 AILQ 202
Score = 57.6 bits (133), Expect = 7e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 28 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SVFP--VEXXXXXXXXXXXXXXXXX 81
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 199
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 200 PSS 202
P S
Sbjct: 214 PPS 216
Score = 57.6 bits (133), Expect = 7e-08
Identities = 24/91 (26%), Positives = 52/91 (57%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+ N +++ P + + L L L+++
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDAS 183
Score = 51.6 bits (118), Expect = 4e-06
Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
Query: 157 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 217 NQEHALIKYTDE-ATTQTSDSNGSLASAMPS-TSRVYGAQALALNATALRLP 266
N+ L E + +T + +G+ +P + V + L+L+A+A+ P
Sbjct: 137 NKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYP 188
Score = 50.8 bits (116), Expect = 8e-06
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 197 EQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQA 255
++ P ++ + + L L ++ N+ L + A +T + ASAM R V GA
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML--AHVRTLEMLSLDASAMVYPPREVCGAGT 197
Query: 256 LAL 258
A+
Sbjct: 198 AAI 200
>AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein
protein.
Length = 723
Score = 62.9 bits (146), Expect = 2e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 210 MFLQ 213
LQ
Sbjct: 199 AILQ 202
Score = 57.6 bits (133), Expect = 7e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 28 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SVFP--VEXXXXXXXXXXXXXXXXX 81
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 199
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 200 PSS 202
P S
Sbjct: 214 PPS 216
Score = 57.6 bits (133), Expect = 7e-08
Identities = 24/91 (26%), Positives = 52/91 (57%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+ N +++ P + + L L L+++
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDAS 183
Score = 51.6 bits (118), Expect = 4e-06
Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
Query: 157 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 217 NQEHALIKYTDE-ATTQTSDSNGSLASAMPS-TSRVYGAQALALNATALRLP 266
N+ L E + +T + +G+ +P + V + L+L+A+A+ P
Sbjct: 137 NKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYP 188
Score = 50.8 bits (116), Expect = 8e-06
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 197 EQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQA 255
++ P ++ + + L L ++ N+ L + A +T + ASAM R V GA
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML--AHVRTLEMLSLDASAMVYPPREVCGAGT 197
Query: 256 LAL 258
A+
Sbjct: 198 AAI 200
>AL445222-17|CAH72930.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 62.9 bits (146), Expect = 2e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 210 MFLQ 213
LQ
Sbjct: 199 AILQ 202
Score = 57.6 bits (133), Expect = 7e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 28 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SVFP--VEXXXXXXXXXXXXXXXXX 81
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 199
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 200 PSS 202
P S
Sbjct: 214 PPS 216
Score = 57.6 bits (133), Expect = 7e-08
Identities = 24/91 (26%), Positives = 52/91 (57%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+ N +++ P + + L L L+++
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDAS 183
Score = 51.6 bits (118), Expect = 4e-06
Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
Query: 157 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 217 NQEHALIKYTDE-ATTQTSDSNGSLASAMPS-TSRVYGAQALALNATALRLP 266
N+ L E + +T + +G+ +P + V + L+L+A+A+ P
Sbjct: 137 NKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYP 188
Score = 50.8 bits (116), Expect = 8e-06
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 197 EQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQA 255
++ P ++ + + L L ++ N+ L + A +T + ASAM R V GA
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML--AHVRTLEMLSLDASAMVYPPREVCGAGT 197
Query: 256 LAL 258
A+
Sbjct: 198 AAI 200
>AL445222-16|CAH72931.1| 696|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 696
Score = 62.9 bits (146), Expect = 2e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 210 MFLQ 213
LQ
Sbjct: 199 AILQ 202
Score = 57.6 bits (133), Expect = 7e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 28 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SVFP--VEXXXXXXXXXXXXXXXXX 81
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 199
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 200 PSS 202
P S
Sbjct: 214 PPS 216
Score = 57.6 bits (133), Expect = 7e-08
Identities = 24/91 (26%), Positives = 52/91 (57%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+ N +++ P + + L L L+++
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDAS 183
Score = 51.6 bits (118), Expect = 4e-06
Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
Query: 157 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 217 NQEHALIKYTDE-ATTQTSDSNGSLASAMPS-TSRVYGAQALALNATALRLP 266
N+ L E + +T + +G+ +P + V + L+L+A+A+ P
Sbjct: 137 NKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYP 188
Score = 50.8 bits (116), Expect = 8e-06
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 197 EQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQA 255
++ P ++ + + L L ++ N+ L + A +T + ASAM R V GA
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML--AHVRTLEMLSLDASAMVYPPREVCGAGT 197
Query: 256 LAL 258
A+
Sbjct: 198 AAI 200
>AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein 1
protein.
Length = 224
Score = 62.9 bits (146), Expect = 2e-09
Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 2/121 (1%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDT 142
PT+I +L+ L +LNL N LN L G L LE N + +P LT L
Sbjct: 26 PTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRA 85
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
N+ + +P ++ L KL+ L+L +N + +LP + +T L +++ NRL P
Sbjct: 86 LYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPE 145
Query: 203 I 203
+
Sbjct: 146 L 146
Score = 59.3 bits (137), Expect = 2e-08
Identities = 44/149 (29%), Positives = 67/149 (44%), Gaps = 4/149 (2%)
Query: 16 LIEQAIAKKKSRLSLNGF--EITEIPGLLYTCLEVEHLYLHKNKISVFP--VEXXXXXXX 71
++ IA+ K+ LN F +I E+P + + +++HL L N+++ P
Sbjct: 1 MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEV 60
Query: 72 XXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIP 131
P L L L LS N +L P+IG L KL+ L +P
Sbjct: 61 LDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLP 120
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSL 160
KEIG+LTQL +GN L +P E+ +L
Sbjct: 121 KEIGELTQLKELHIQGNRLTVLPPELGNL 149
Score = 56.0 bits (129), Expect = 2e-07
Identities = 38/148 (25%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+P + +E L N+I P + P G+L L L
Sbjct: 2 VPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVL 61
Query: 98 NLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
+L+YN L N L L L A + + + +P +IGKLT+L R N+L ++P+
Sbjct: 62 DLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPK 121
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRM 183
E+ L +L+ L ++ N++ LP + +
Sbjct: 122 EIGELTQLKELHIQGNRLTVLPPELGNL 149
Score = 44.8 bits (101), Expect = 5e-04
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 130 IPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHC 189
+P I +L L+ N+++ +P +++SL KL+ L L N++ TLP + AL
Sbjct: 2 VPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVL 61
Query: 190 NLRNNRLEQ--FPSSILKCKELMFLQLNSN 217
+L N L + P + L L L+ N
Sbjct: 62 DLTYNNLSENSLPGNFFYLTTLRALYLSDN 91
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/88 (27%), Positives = 35/88 (39%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 63 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 122
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 115
IG L L L++ N L VL PE+G+L+
Sbjct: 123 IGELTQLKELHIQGNRLTVLPPELGNLD 150
>AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens
cDNA FLJ34270 fis, clone FEBRA2003100. ).
Length = 723
Score = 62.9 bits (146), Expect = 2e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 210 MFLQ 213
LQ
Sbjct: 199 AILQ 202
Score = 57.6 bits (133), Expect = 7e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 28 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SVFP--VEXXXXXXXXXXXXXXXXX 81
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 199
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 200 PSS 202
P S
Sbjct: 214 PPS 216
Score = 57.6 bits (133), Expect = 7e-08
Identities = 24/91 (26%), Positives = 52/91 (57%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+ N +++ P + + L L L+++
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDAS 183
Score = 51.6 bits (118), Expect = 4e-06
Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
Query: 157 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 217 NQEHALIKYTDE-ATTQTSDSNGSLASAMPS-TSRVYGAQALALNATALRLP 266
N+ L E + +T + +G+ +P + V + L+L+A+A+ P
Sbjct: 137 NKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYP 188
Score = 50.8 bits (116), Expect = 8e-06
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 197 EQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQA 255
++ P ++ + + L L ++ N+ L + A +T + ASAM R V GA
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML--AHVRTLEMLSLDASAMVYPPREVCGAGT 197
Query: 256 LAL 258
A+
Sbjct: 198 AAI 200
>AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens
cDNA FLJ31641 fis, clone NT2RI2003695, weakly similar to
TRICHOHYALIN. ).
Length = 696
Score = 62.9 bits (146), Expect = 2e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 210 MFLQ 213
LQ
Sbjct: 199 AILQ 202
Score = 57.6 bits (133), Expect = 7e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Query: 28 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SVFP--VEXXXXXXXXXXXXXXXXX 81
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 141
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 142 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 199
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 200 PSS 202
P S
Sbjct: 214 PPS 216
Score = 57.6 bits (133), Expect = 7e-08
Identities = 24/91 (26%), Positives = 52/91 (57%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N+ N +++ P + + L L L+++
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDAS 183
Score = 51.6 bits (118), Expect = 4e-06
Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
Query: 157 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 217 NQEHALIKYTDE-ATTQTSDSNGSLASAMPS-TSRVYGAQALALNATALRLP 266
N+ L E + +T + +G+ +P + V + L+L+A+A+ P
Sbjct: 137 NKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYP 188
Score = 50.8 bits (116), Expect = 8e-06
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 197 EQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQA 255
++ P ++ + + L L ++ N+ L + A +T + ASAM R V GA
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML--AHVRTLEMLSLDASAMVYPPREVCGAGT 197
Query: 256 LAL 258
A+
Sbjct: 198 AAI 200
>AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and
death domain containing protein protein.
Length = 753
Score = 62.1 bits (144), Expect = 3e-09
Identities = 31/91 (34%), Positives = 52/91 (57%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+P+ +G L L N L+T+P + +L+ L+ L L N ++TLP + + +L
Sbjct: 14 LSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSL 73
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+ NL +NRL+ P+S+ + L L L+SN
Sbjct: 74 LELNLASNRLQSLPASLAGLRSLRLLVLHSN 104
Score = 54.8 bits (126), Expect = 5e-07
Identities = 37/128 (28%), Positives = 61/128 (47%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
++ L L LS+N L+ L +G L L L+ +P +G L+ L N L
Sbjct: 1 MRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLL 60
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 210
T+P E+ L L L L +N++++LP ++ + +L L +N L P+ + + L
Sbjct: 61 DTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLT 120
Query: 211 FLQLNSNQ 218
L L NQ
Sbjct: 121 RLDLRDNQ 128
Score = 47.2 bits (107), Expect = 9e-05
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 4/145 (2%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
++E+P L + L + N++ P P EIG L +L
Sbjct: 14 LSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSL 73
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ LNL+ N L L + L L + L +P ++ +L L R N+L+ +P
Sbjct: 74 LELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLP 133
Query: 155 EEMTSLAKLRWLTLENNQI-ETLPD 178
E+ +R L+ N + E PD
Sbjct: 134 PELLDAPFVR---LQGNPLGEASPD 155
Score = 44.8 bits (101), Expect = 5e-04
Identities = 24/75 (32%), Positives = 41/75 (54%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N L +PE + +L L +LT+ +N+++TLP + ++ L +L N L+ P I
Sbjct: 12 NCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLG 71
Query: 208 ELMFLQLNSNQEHAL 222
L+ L L SN+ +L
Sbjct: 72 SLLELNLASNRLQSL 86
>BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein.
Length = 529
Score = 60.9 bits (141), Expect = 7e-09
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L+ LNLS+N L+ EI L+ L+ +KEIP EI +L L F N + +
Sbjct: 347 LIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVL 406
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P + SL+ L L + N++ +P+ + ++ +L + N L FP ILK L +Q
Sbjct: 407 PIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKL-NLTKIQ 465
Query: 214 LNSNQEH 220
+N H
Sbjct: 466 FENNFTH 472
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/147 (28%), Positives = 60/147 (40%), Gaps = 1/147 (0%)
Query: 25 KSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX 84
++ L+L GF I P L ++ +L L N + FP E
Sbjct: 324 RNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEI 383
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+EI L+ L +++N + VL + L LE + L IP EI KL L+
Sbjct: 384 PSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLT 443
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENN 171
GNEL P + L L + ENN
Sbjct: 444 VDGNELSFFPHGILKL-NLTKIQFENN 469
Score = 32.7 bits (71), Expect = 2.1
Identities = 19/52 (36%), Positives = 25/52 (48%)
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L L+ I PD L++ NL N L FP+ IL K L L+L +N
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNN 378
>AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich
repeat protein SHOC-2 (Ras-binding protein Sur-8)
protein.
Length = 506
Score = 60.9 bits (141), Expect = 7e-09
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L+ LNLS+N L+ EI L+ L+ +KEIP EI +L L F N + +
Sbjct: 347 LIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVL 406
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P + SL+ L L + N++ +P+ + ++ +L + N L FP ILK L +Q
Sbjct: 407 PIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKL-NLTKIQ 465
Query: 214 LNSNQEH 220
+N H
Sbjct: 466 FENNFTH 472
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/147 (28%), Positives = 60/147 (40%), Gaps = 1/147 (0%)
Query: 25 KSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX 84
++ L+L GF I P L ++ +L L N + FP E
Sbjct: 324 RNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEI 383
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+EI L+ L +++N + VL + L LE + L IP EI KL L+
Sbjct: 384 PSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLT 443
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENN 171
GNEL P + L L + ENN
Sbjct: 444 VDGNELSFFPHGILKL-NLTKIQFENN 469
Score = 32.7 bits (71), Expect = 2.1
Identities = 19/52 (36%), Positives = 25/52 (48%)
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L L+ I PD L++ NL N L FP+ IL K L L+L +N
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNN 378
>AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich
repeat protein SHOC-2 (Ras-binding protein Sur-8)
protein.
Length = 506
Score = 60.9 bits (141), Expect = 7e-09
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L+ LNLS+N L+ EI L+ L+ +KEIP EI +L L F N + +
Sbjct: 347 LIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVL 406
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P + SL+ L L + N++ +P+ + ++ +L + N L FP ILK L +Q
Sbjct: 407 PIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKL-NLTKIQ 465
Query: 214 LNSNQEH 220
+N H
Sbjct: 466 FENNFTH 472
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/147 (28%), Positives = 60/147 (40%), Gaps = 1/147 (0%)
Query: 25 KSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX 84
++ L+L GF I P L ++ +L L N + FP E
Sbjct: 324 RNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEI 383
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P+EI L+ L +++N + VL + L LE + L IP EI KL L+
Sbjct: 384 PSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLT 443
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENN 171
GNEL P + L L + ENN
Sbjct: 444 VDGNELSFFPHGILKL-NLTKIQFENN 469
Score = 32.7 bits (71), Expect = 2.1
Identities = 19/52 (36%), Positives = 25/52 (48%)
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L L+ I PD L++ NL N L FP+ IL K L L+L +N
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNN 378
>BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 3 protein.
Length = 712
Score = 60.1 bits (139), Expect = 1e-08
Identities = 56/191 (29%), Positives = 80/191 (41%), Gaps = 3/191 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXP 85
+R L+ ++EIP + +E+L L++N I P P
Sbjct: 85 TRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLP 144
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
+ NL V L S N L L EIG L L + ++ IP +IG L L
Sbjct: 145 VHLCNLPLKV-LIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNV 203
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI-L 204
R N L +PEE+ L +R L N+I T+P + L L NN L+ P+ I +
Sbjct: 204 RRNHLVHLPEELAELPLIR-LDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQICI 262
Query: 205 KCKELMFLQLN 215
K K +F LN
Sbjct: 263 KGKVHIFKYLN 273
Score = 44.8 bits (101), Expect = 5e-04
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+R L EIP E L+ N ++ IPE + +L L +L + NQ+ TLP +
Sbjct: 90 SRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCN 149
Query: 183 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
+ V NN+L P I + LM L ++ N+
Sbjct: 150 LPLKV-LIASNNKLVSLPEEIGHLRHLMELDVSCNE 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 2/180 (1%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + +LS N L+ + E LE + ++ IP+ I L L N+
Sbjct: 80 DLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQ 139
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L T+P + +L L+ L NN++ +LP+ + + L+ ++ N ++ PS I + L
Sbjct: 140 LSTLPVHLCNLP-LKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEAL 198
Query: 210 MFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQALALNATALRLPAA 268
L + N L + E D + + + +P R + Q + L+ L+ P A
Sbjct: 199 RDLNVRRNHLVHLPEELAELPLIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPA 258
>AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ42687 fis, clone BRAMY3001794, moderately
similar to Rattus norvegicus SCN circadian oscillatory
protein (Scop). ).
Length = 423
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/114 (34%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
Query: 94 LVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L LNLS+N L +L+ EI L +L CN G ++P +IG L L T GN L
Sbjct: 301 LKGLNLSHNKLGLFPILLCEISTLTELNLS-CN--GFHDLPSQIGNLLNLQTLCLDGNFL 357
Query: 151 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
T+PEE+ +L +L L + N +P+ +++T L + N LE +L
Sbjct: 358 TTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVL 411
Score = 54.0 bits (124), Expect = 8e-07
Identities = 34/112 (30%), Positives = 52/112 (46%)
Query: 42 LYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 101
LY +++ L L NK+ +FP+ P++IGNL NL L L
Sbjct: 295 LYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDG 354
Query: 102 NPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
N L L E+G+L++L + + +IP+ KLT LD GN L+ +
Sbjct: 355 NFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVL 406
Score = 54.0 bits (124), Expect = 8e-07
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + + L LNLS N + L +IG+L L+ + L +P+E+G L QL + G
Sbjct: 315 PILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLG 374
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLR 192
N IPE L L + + N +E L ++RM + H +LR
Sbjct: 375 ISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLR 423
Score = 31.9 bits (69), Expect = 3.7
Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 150 LKTIPEEMTSLAKLRWLTLENN--QIETLP--DTMDRMTALVHCNLRNNRLEQFPSSILK 205
L+ +PE + + +L L +N Q+E DT+ + + L NL +N+L FP + +
Sbjct: 261 LEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCE 320
Query: 206 CKELMFLQLNSNQEHAL-IKYTDEATTQTSDSNGSLASAMP 245
L L L+ N H L + + QT +G+ + +P
Sbjct: 321 ISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLP 361
>BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte
differentiation 158 protein.
Length = 803
Score = 58.8 bits (136), Expect = 3e-08
Identities = 41/186 (22%), Positives = 78/186 (41%), Gaps = 2/186 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFP--VEXXXXXXXXXXXXXXXXXXX 83
+ L L ++ IP +++ L ++ L L +N + V
Sbjct: 592 TELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITY 651
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P I L +L L+ S+N + VL + K+ + ++ IP EIG L L F
Sbjct: 652 IPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYF 711
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N+++++P+E+ KL+ L + N + L + + L + +++ N E P +
Sbjct: 712 SITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPEL 771
Query: 204 LKCKEL 209
C+ L
Sbjct: 772 GDCRAL 777
Score = 58.4 bits (135), Expect = 4e-08
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P + +L +L L+L N L + I L KL + IP+ I KLT L+
Sbjct: 605 PHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLER 664
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
N+++ +P + K+R+L L N I +P + + +L + ++ N++E P
Sbjct: 665 LSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDE 724
Query: 203 ILKCKELMFLQLNSN 217
+ CK+L L++ N
Sbjct: 725 LYFCKKLKTLKIGKN 739
Score = 52.4 bits (120), Expect = 2e-06
Identities = 47/183 (25%), Positives = 80/183 (43%), Gaps = 8/183 (4%)
Query: 8 IRENHILALIEQAIA----KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV 63
++EN++ + IE+ ++ +K + L L IT IP + +E L NKI V P
Sbjct: 619 LKENNLKS-IEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPS 677
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN 123
P EIG L++L +++ N + L E+ +KL+
Sbjct: 678 HLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIG 737
Query: 124 RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR--WLTLENNQIETLP-DTM 180
+ L + +IG L L +GN + +P E+ L+ L +E+ ETLP D
Sbjct: 738 KNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGDCRALKRAGLVVEDALFETLPSDVR 797
Query: 181 DRM 183
++M
Sbjct: 798 EQM 800
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/157 (24%), Positives = 64/157 (40%), Gaps = 6/157 (3%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPE 110
L L N I+ P P+ + + L+LSYN + + PE
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 111 IGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTL 168
IG L+ L+ F CN++ + +P E+ +L T N L + ++ +L L +L +
Sbjct: 702 IGVLQSLQYFSITCNKV--ESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDV 759
Query: 169 ENNQIETLPDTMDRMTALVHCNL--RNNRLEQFPSSI 203
+ N E LP + AL L + E PS +
Sbjct: 760 KGNHFEILPPELGDCRALKRAGLVVEDALFETLPSDV 796
Score = 41.1 bits (92), Expect = 0.006
Identities = 28/128 (21%), Positives = 55/128 (42%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L+ L L L +N + + I L LE + ++ +P + ++ N+
Sbjct: 635 HLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYND 694
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
++ IP E+ L L++ ++ N++E+LPD + L + N L I L
Sbjct: 695 IRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFL 754
Query: 210 MFLQLNSN 217
+L + N
Sbjct: 755 SYLDVKGN 762
Score = 39.5 bits (88), Expect = 0.019
Identities = 34/140 (24%), Positives = 57/140 (40%), Gaps = 5/140 (3%)
Query: 88 IGNLK---NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG--KLTQLDT 142
+ NLK NL L L + L + + L L+ LK I + + L +L
Sbjct: 582 LNNLKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTV 641
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
N + IPE + L L L+ +N+IE LP + + + +L N + P
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 203 ILKCKELMFLQLNSNQEHAL 222
I + L + + N+ +L
Sbjct: 702 IGVLQSLQYFSITCNKVESL 721
>AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein.
Length = 803
Score = 58.8 bits (136), Expect = 3e-08
Identities = 41/186 (22%), Positives = 78/186 (41%), Gaps = 2/186 (1%)
Query: 26 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFP--VEXXXXXXXXXXXXXXXXXXX 83
+ L L ++ IP +++ L ++ L L +N + V
Sbjct: 592 TELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITY 651
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P I L +L L+ S+N + VL + K+ + ++ IP EIG L L F
Sbjct: 652 IPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYF 711
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N+++++P+E+ KL+ L + N + L + + L + +++ N E P +
Sbjct: 712 SITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPEL 771
Query: 204 LKCKEL 209
C+ L
Sbjct: 772 GDCRAL 777
Score = 58.4 bits (135), Expect = 4e-08
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 142
P + +L +L L+L N L + I L KL + IP+ I KLT L+
Sbjct: 605 PHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLER 664
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
N+++ +P + K+R+L L N I +P + + +L + ++ N++E P
Sbjct: 665 LSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDE 724
Query: 203 ILKCKELMFLQLNSN 217
+ CK+L L++ N
Sbjct: 725 LYFCKKLKTLKIGKN 739
Score = 52.4 bits (120), Expect = 2e-06
Identities = 47/183 (25%), Positives = 80/183 (43%), Gaps = 8/183 (4%)
Query: 8 IRENHILALIEQAIA----KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV 63
++EN++ + IE+ ++ +K + L L IT IP + +E L NKI V P
Sbjct: 619 LKENNLKS-IEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPS 677
Query: 64 EXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN 123
P EIG L++L +++ N + L E+ +KL+
Sbjct: 678 HLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIG 737
Query: 124 RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR--WLTLENNQIETLP-DTM 180
+ L + +IG L L +GN + +P E+ L+ L +E+ ETLP D
Sbjct: 738 KNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGDCRALKRAGLVVEDALFETLPSDVR 797
Query: 181 DRM 183
++M
Sbjct: 798 EQM 800
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/157 (24%), Positives = 64/157 (40%), Gaps = 6/157 (3%)
Query: 51 LYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPE 110
L L N I+ P P+ + + L+LSYN + + PE
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 111 IGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTL 168
IG L+ L+ F CN++ + +P E+ +L T N L + ++ +L L +L +
Sbjct: 702 IGVLQSLQYFSITCNKV--ESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDV 759
Query: 169 ENNQIETLPDTMDRMTALVHCNL--RNNRLEQFPSSI 203
+ N E LP + AL L + E PS +
Sbjct: 760 KGNHFEILPPELGDCRALKRAGLVVEDALFETLPSDV 796
Score = 41.1 bits (92), Expect = 0.006
Identities = 28/128 (21%), Positives = 55/128 (42%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L+ L L L +N + + I L LE + ++ +P + ++ N+
Sbjct: 635 HLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYND 694
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
++ IP E+ L L++ ++ N++E+LPD + L + N L I L
Sbjct: 695 IRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFL 754
Query: 210 MFLQLNSN 217
+L + N
Sbjct: 755 SYLDVKGN 762
Score = 39.5 bits (88), Expect = 0.019
Identities = 34/140 (24%), Positives = 57/140 (40%), Gaps = 5/140 (3%)
Query: 88 IGNLK---NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIG--KLTQLDT 142
+ NLK NL L L + L + + L L+ LK I + + L +L
Sbjct: 582 LNNLKKMTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTV 641
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
N + IPE + L L L+ +N+IE LP + + + +L N + P
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 203 ILKCKELMFLQLNSNQEHAL 222
I + L + + N+ +L
Sbjct: 702 IGVLQSLQYFSITCNKVESL 721
>AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 58.4 bits (135), Expect = 4e-08
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 2/124 (1%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L LN+S N L+ L + DL L+ + L IP+EIGKL L NE++ +
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P++M L LR L + N + LPD + + LV + N++ + P K L +
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDL-PLVKLDFSCNKVTEIPVCYRKLHHLQVII 119
Query: 214 LNSN 217
L++N
Sbjct: 120 LDNN 123
Score = 44.8 bits (101), Expect = 5e-04
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 8/152 (5%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
++ +P L+ L ++ L + NK+ P E P ++G L +L
Sbjct: 12 LSTLPKYLFD-LPLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSL 70
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
LN+ N L+VL E+GDL ++ F CN++ EIP KL L N L+
Sbjct: 71 RELNIRRNNLHVLPDELGDLPLVKLDFSCNKV--TEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 154 PEEMTSLAKLRWLTLENNQ----IETLPDTMD 181
P ++ K+ N Q ++ PD++D
Sbjct: 129 PAQICLKGKVHIFKYLNIQACCRMDKKPDSLD 160
Score = 40.7 bits (91), Expect = 0.008
Identities = 27/122 (22%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N L T+P+ + L L+ L + NN++ ++P+ + ++ L+ ++ N ++ P + K
Sbjct: 10 NLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLH 68
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQALALNATALRLP 266
L L + N H L + D + + + +P R ++ Q + L+ L++P
Sbjct: 69 SLRELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 267 AA 268
A
Sbjct: 129 PA 130
>AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 58.4 bits (135), Expect = 4e-08
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 2/124 (1%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L LN+S N L+ L + DL L+ + L IP+EIGKL L NE++ +
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P++M L LR L + N + LPD + + LV + N++ + P K L +
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDL-PLVKLDFSCNKVTEIPVCYRKLHHLQVII 119
Query: 214 LNSN 217
L++N
Sbjct: 120 LDNN 123
Score = 44.8 bits (101), Expect = 5e-04
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 8/152 (5%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
++ +P L+ L ++ L + NK+ P E P ++G L +L
Sbjct: 12 LSTLPKYLFD-LPLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSL 70
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
LN+ N L+VL E+GDL ++ F CN++ EIP KL L N L+
Sbjct: 71 RELNIRRNNLHVLPDELGDLPLVKLDFSCNKV--TEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 154 PEEMTSLAKLRWLTLENNQ----IETLPDTMD 181
P ++ K+ N Q ++ PD++D
Sbjct: 129 PAQICLKGKVHIFKYLNIQACCRMDKKPDSLD 160
Score = 40.7 bits (91), Expect = 0.008
Identities = 27/122 (22%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N L T+P+ + L L+ L + NN++ ++P+ + ++ L+ ++ N ++ P + K
Sbjct: 10 NLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLH 68
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQALALNATALRLP 266
L L + N H L + D + + + +P R ++ Q + L+ L++P
Sbjct: 69 SLRELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 267 AA 268
A
Sbjct: 129 PA 130
>AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 58.4 bits (135), Expect = 4e-08
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 2/124 (1%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L LN+S N L+ L + DL L+ + L IP+EIGKL L NE++ +
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
P++M L LR L + N + LPD + + LV + N++ + P K L +
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDL-PLVKLDFSCNKVTEIPVCYRKLHHLQVII 119
Query: 214 LNSN 217
L++N
Sbjct: 120 LDNN 123
Score = 44.8 bits (101), Expect = 5e-04
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 8/152 (5%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
++ +P L+ L ++ L + NK+ P E P ++G L +L
Sbjct: 12 LSTLPKYLFD-LPLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSL 70
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
LN+ N L+VL E+GDL ++ F CN++ EIP KL L N L+
Sbjct: 71 RELNIRRNNLHVLPDELGDLPLVKLDFSCNKV--TEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 154 PEEMTSLAKLRWLTLENNQ----IETLPDTMD 181
P ++ K+ N Q ++ PD++D
Sbjct: 129 PAQICLKGKVHIFKYLNIQACCRMDKKPDSLD 160
Score = 40.7 bits (91), Expect = 0.008
Identities = 27/122 (22%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N L T+P+ + L L+ L + NN++ ++P+ + ++ L+ ++ N ++ P + K
Sbjct: 10 NLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLH 68
Query: 208 ELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQALALNATALRLP 266
L L + N H L + D + + + +P R ++ Q + L+ L++P
Sbjct: 69 SLRELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 267 AA 268
A
Sbjct: 129 PA 130
>AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar to
Ras suppressor protein 1r 4 (tax-transcriptionally act
protein.
Length = 146
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE--IPKEIGKLTQLDT 142
PT+I L+ L +LNL N LN+ G L LE L E +P LT L
Sbjct: 25 PTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVLDLTYNNLNENYLPGNFFYLTTLCA 84
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
N+ + +P ++ L KL+ L+ +N + +LP + +T L +++ NRL P
Sbjct: 85 LYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPKEIRVLTQLKELHIQGNRLTVLPPE 144
Query: 203 I 203
+
Sbjct: 145 L 145
Score = 51.6 bits (118), Expect = 4e-06
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 2/142 (1%)
Query: 38 IPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 97
+P + +E L N+I P + P G+L L L
Sbjct: 1 VPPNIAELKNLEVLNFLNNQIEKLPTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVL 60
Query: 98 NLSYNPLN--VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
+L+YN LN L L L A + + + +P +IGKLT+L R N L ++P+
Sbjct: 61 DLTYNNLNENYLPGNFFYLTTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPK 120
Query: 156 EMTSLAKLRWLTLENNQIETLP 177
E+ L +L+ L ++ N++ LP
Sbjct: 121 EIRVLTQLKELHIQGNRLTVLP 142
Score = 48.4 bits (110), Expect = 4e-05
Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 2/126 (1%)
Query: 34 EITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXX--XXXXXXXXXXXXXXXXXPTEIGNL 91
+I ++P + +++HL L N++++ P P L
Sbjct: 20 QIEKLPTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVLDLTYNNLNENYLPGNFFYL 79
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
L L LS N +L P+IG L KL+ L +PKEI LTQL +GN L
Sbjct: 80 TTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPKEIRVLTQLKELHIQGNRLT 139
Query: 152 TIPEEM 157
+P E+
Sbjct: 140 VLPPEL 145
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 153 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI--LKCKELM 210
+P + L L L NNQIE LP + R+ L H NL NRL P L E++
Sbjct: 1 VPPNIAELKNLEVLNFLNNQIEKLPTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVL 60
Query: 211 FLQLNSNQEHAL 222
L N+ E+ L
Sbjct: 61 DLTYNNLNENYL 72
Score = 33.5 bits (73), Expect = 1.2
Identities = 22/85 (25%), Positives = 31/85 (36%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L+ N +PG + + LYL N + P + P E
Sbjct: 62 LTYNNLNENYLPGNFFYLTTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPKE 121
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIG 112
I L L L++ N L VL PE+G
Sbjct: 122 IRVLTQLKELHIQGNRLTVLPPELG 146
>BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 55.2 bits (127), Expect = 3e-07
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 127 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L E+P KE+ L + N+L T+P + L L L L N+++ LP R+
Sbjct: 27 LNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVN 86
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L H +L NN+L P S + K L +L L N
Sbjct: 87 LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDN 118
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/88 (28%), Positives = 42/88 (47%)
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
E+ L L+LS N L L + L L ++ L+++P + G+L L
Sbjct: 34 ELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLL 93
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIE 174
N+L T+P L L+WL L++N ++
Sbjct: 94 NNKLVTLPVSFAQLKNLKWLDLKDNPLD 121
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
Query: 89 GNLKNLVN---LNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
GNL++ ++ L+LS + LN V + E+ L K + L +P + LT L
Sbjct: 9 GNLRDKLDGNELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLD 68
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
N+L+ +P + L L+ L L NN++ TLP + ++ L +L++N L+
Sbjct: 69 LSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLD 121
Score = 41.1 bits (92), Expect = 0.006
Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 148 NELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
++L +P +E+ +L K L L N++ TLP +T LV +L N+L+Q P+ +
Sbjct: 25 SDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRL 84
Query: 207 KELMFLQLNSNQ 218
L L L +N+
Sbjct: 85 VNLQHLDLLNNK 96
Score = 33.1 bits (72), Expect = 1.6
Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 1/97 (1%)
Query: 18 EQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXX 77
E A K + L L+ ++T +P + L L KNK+ P +
Sbjct: 34 ELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLL 93
Query: 78 XXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEI-GD 113
P LKNL L+L NPL+ ++ ++ GD
Sbjct: 94 NNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVAGD 130
>BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 55.2 bits (127), Expect = 3e-07
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 127 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L E+P KE+ L + N+L T+P + L L L L N+++ LP R+
Sbjct: 27 LNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVN 86
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L H +L NN+L P S + K L +L L N
Sbjct: 87 LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDN 118
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/88 (28%), Positives = 42/88 (47%)
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
E+ L L+LS N L L + L L ++ L+++P + G+L L
Sbjct: 34 ELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLL 93
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIE 174
N+L T+P L L+WL L++N ++
Sbjct: 94 NNKLVTLPVSFAQLKNLKWLDLKDNPLD 121
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
Query: 89 GNLKNLVN---LNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
GNL++ ++ L+LS + LN V + E+ L K + L +P + LT L
Sbjct: 9 GNLRDKLDGNELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLD 68
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
N+L+ +P + L L+ L L NN++ TLP + ++ L +L++N L+
Sbjct: 69 LSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLD 121
Score = 41.1 bits (92), Expect = 0.006
Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 148 NELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 206
++L +P +E+ +L K L L N++ TLP +T LV +L N+L+Q P+ +
Sbjct: 25 SDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRL 84
Query: 207 KELMFLQLNSNQ 218
L L L +N+
Sbjct: 85 VNLQHLDLLNNK 96
Score = 33.1 bits (72), Expect = 1.6
Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 1/97 (1%)
Query: 18 EQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXX 77
E A K + L L+ ++T +P + L L KNK+ P +
Sbjct: 34 ELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLL 93
Query: 78 XXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEI-GD 113
P LKNL L+L NPL+ ++ ++ GD
Sbjct: 94 NNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVAGD 130
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 54.4 bits (125), Expect = 6e-07
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 39 PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLN 98
PGL + ++ LYL N IS P P+ L L L
Sbjct: 238 PGLFHNNHNLQRLYLSNNHISQLP----------------------PSVFMQLPQLNRLT 275
Query: 99 LSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNELKTI-PE 155
L N L L P I G + L W + +P + L QL N++ I P
Sbjct: 276 LFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPG 335
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTA-LVHCNLRNNRLEQFPSSIL-KCKELMFLQ 213
L +LR L+L N ++ L + RM A L + +L+NNRL Q P +I LM +Q
Sbjct: 336 AFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQ 395
Query: 214 LNSNQ 218
L +NQ
Sbjct: 396 LQNNQ 400
Score = 39.1 bits (87), Expect = 0.025
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 3/73 (4%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF-PSSIL 204
NEL I P +L LR+L+L NN+++ LP + +L L +N+L Q P+
Sbjct: 87 NELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFS 146
Query: 205 KCKELMFLQLNSN 217
+C L LQL+ N
Sbjct: 147 QCSNLKELQLHGN 159
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 54.4 bits (125), Expect = 6e-07
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 39 PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLN 98
PGL + ++ LYL N IS P P+ L L L
Sbjct: 238 PGLFHNNHNLQRLYLSNNHISQLP----------------------PSVFMQLPQLNRLT 275
Query: 99 LSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNELKTI-PE 155
L N L L P I G + L W + +P + L QL N++ I P
Sbjct: 276 LFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPG 335
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTA-LVHCNLRNNRLEQFPSSIL-KCKELMFLQ 213
L +LR L+L N ++ L + RM A L + +L+NNRL Q P +I LM +Q
Sbjct: 336 AFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQ 395
Query: 214 LNSNQ 218
L +NQ
Sbjct: 396 LQNNQ 400
Score = 39.1 bits (87), Expect = 0.025
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 3/73 (4%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF-PSSIL 204
NEL I P +L LR+L+L NN+++ LP + +L L +N+L Q P+
Sbjct: 87 NELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFS 146
Query: 205 KCKELMFLQLNSN 217
+C L LQL+ N
Sbjct: 147 QCSNLKELQLHGN 159
>BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 54.0 bits (124), Expect = 8e-07
Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 14 LALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV--------EX 65
L + + +++ S + L+ + +P L+ ++ HL L +N + P E
Sbjct: 116 LRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNEL 175
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P + ++ L LN+S N L + +G + L+ F +
Sbjct: 176 QRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGN 235
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMT 184
L+ +P E+ + QL G NE IPE + L + L + N +ETL + +M
Sbjct: 236 FLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMP 295
Query: 185 ALVHCNLRNN 194
+ H +LR N
Sbjct: 296 HIKHVDLRLN 305
Score = 52.8 bits (121), Expect = 2e-06
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Query: 87 EIGNLKNLVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
E+ L +LNLS N L + + I L +L CN L+ +P +G + L TF
Sbjct: 174 ELQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVS-CN--ALRSVPAAVGVMHNLQTF 230
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-SS 202
GN L+++P E+ ++ +L +L L N+ +P+ ++++TA+ + N +E +
Sbjct: 231 LLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQA 290
Query: 203 ILKCKELMFLQLNSNQEHALI 223
+ K + + L N LI
Sbjct: 291 LRKMPHIKHVDLRLNVIRKLI 311
Score = 43.2 bits (97), Expect = 0.002
Identities = 25/100 (25%), Positives = 51/100 (51%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 390 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 449
Query: 183 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ V N LE P+ ++K L FL ++N+ +L
Sbjct: 450 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESL 489
Score = 35.9 bits (79), Expect = 0.23
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 6/131 (4%)
Query: 127 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L+ P ++ KL +L+ GN+LK IP + + ++ + +N IE P+ M ++
Sbjct: 536 LQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVM-QLPE 594
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMP 245
+ +L N L + +L L L N L D T + ++ P
Sbjct: 595 IKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL----DHKTLELLNNIRCFKIDQP 650
Query: 246 STSRVYGAQAL 256
ST GA A+
Sbjct: 651 STGDASGAPAV 661
>BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 54.0 bits (124), Expect = 8e-07
Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 14 LALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV--------EX 65
L + + +++ S + L+ + +P L+ ++ HL L +N + P E
Sbjct: 116 LRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNEL 175
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P + ++ L LN+S N L + +G + L+ F +
Sbjct: 176 QRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGN 235
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMT 184
L+ +P E+ + QL G NE IPE + L + L + N +ETL + +M
Sbjct: 236 FLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMP 295
Query: 185 ALVHCNLRNN 194
+ H +LR N
Sbjct: 296 HIKHVDLRLN 305
Score = 52.8 bits (121), Expect = 2e-06
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Query: 87 EIGNLKNLVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
E+ L +LNLS N L + + I L +L CN L+ +P +G + L TF
Sbjct: 174 ELQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVS-CN--ALRSVPAAVGVMHNLQTF 230
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-SS 202
GN L+++P E+ ++ +L +L L N+ +P+ ++++TA+ + N +E +
Sbjct: 231 LLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQA 290
Query: 203 ILKCKELMFLQLNSNQEHALI 223
+ K + + L N LI
Sbjct: 291 LRKMPHIKHVDLRLNVIRKLI 311
Score = 43.2 bits (97), Expect = 0.002
Identities = 25/100 (25%), Positives = 51/100 (51%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 390 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 449
Query: 183 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ V N LE P+ ++K L FL ++N+ +L
Sbjct: 450 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESL 489
Score = 35.9 bits (79), Expect = 0.23
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 6/131 (4%)
Query: 127 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L+ P ++ KL +L+ GN+LK IP + + ++ + +N IE P+ M ++
Sbjct: 536 LQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVM-QLPE 594
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMP 245
+ +L N L + +L L L N L D T + ++ P
Sbjct: 595 IKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL----DHKTLELLNNIRCFKIDQP 650
Query: 246 STSRVYGAQAL 256
ST GA A+
Sbjct: 651 STGDASGAPAV 661
>AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ11062 fis, clone PLACE1004804, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 721
Score = 54.0 bits (124), Expect = 8e-07
Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 14 LALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV--------EX 65
L + + +++ S + L+ + +P L+ ++ HL L +N + P E
Sbjct: 116 LRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNEL 175
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P + ++ L LN+S N L + +G + L+ F +
Sbjct: 176 QRFAKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGN 235
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMT 184
L+ +P E+ + QL G NE IPE + L + L + N +ETL + +M
Sbjct: 236 FLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMP 295
Query: 185 ALVHCNLRNN 194
+ H +LR N
Sbjct: 296 HIKHVDLRLN 305
Score = 52.8 bits (121), Expect = 2e-06
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Query: 87 EIGNLKNLVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
E+ L +LNLS N L + + I L +L CN L+ +P +G + L TF
Sbjct: 174 ELQRFAKLKSLNLSNNHLGDFPLAVCSIPTLAELNVS-CN--ALRSVPAAVGVMHNLQTF 230
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-SS 202
GN L+++P E+ ++ +L +L L N+ +P+ ++++TA+ + N +E +
Sbjct: 231 LLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQA 290
Query: 203 ILKCKELMFLQLNSNQEHALI 223
+ K + + L N LI
Sbjct: 291 LRKMPHIKHVDLRLNVIRKLI 311
Score = 43.2 bits (97), Expect = 0.002
Identities = 25/100 (25%), Positives = 51/100 (51%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 390 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 449
Query: 183 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ V N LE P+ ++K L FL ++N+ +L
Sbjct: 450 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESL 489
Score = 35.9 bits (79), Expect = 0.23
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 6/131 (4%)
Query: 127 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L+ P ++ KL +L+ GN+LK IP + + ++ + +N IE P+ M ++
Sbjct: 536 LQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVM-QLPE 594
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMP 245
+ +L N L + +L L L N L D T + ++ P
Sbjct: 595 IKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL----DHKTLELLNNIRCFKIDQP 650
Query: 246 STSRVYGAQAL 256
ST GA A+
Sbjct: 651 STGDASGAPAV 661
>AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein.
Length = 575
Score = 54.0 bits (124), Expect = 8e-07
Identities = 28/66 (42%), Positives = 39/66 (59%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P++I L NLV L+LS N + L E+G++ L N L+ +P E+GKL QL T G
Sbjct: 85 PSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLG 144
Query: 145 ARGNEL 150
+GN L
Sbjct: 145 LKGNPL 150
Score = 48.4 bits (110), Expect = 4e-05
Identities = 27/91 (29%), Positives = 42/91 (46%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
++ + + LT L N L IP ++ L L +L L +N+I +LP + M +L
Sbjct: 58 VRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSL 117
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
+L NN L P + K +L L L N
Sbjct: 118 RELHLNNNLLRVLPFELGKLFQLQTLGLKGN 148
Score = 46.4 bits (105), Expect = 2e-04
Identities = 27/92 (29%), Positives = 43/92 (46%)
Query: 107 LIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWL 166
L + L L A + L IP +I KL L N+++++P E+ ++ LR L
Sbjct: 61 LSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLREL 120
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQ 198
L NN + LP + ++ L L+ N L Q
Sbjct: 121 HLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQ 152
Score = 45.2 bits (102), Expect = 4e-04
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Query: 155 EEMTSLAKLRWLTLE-NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
EE + K W LE + ++ +L ++ +T L +L +N L + PS I K L++L
Sbjct: 39 EEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLD 98
Query: 214 LNSNQEHAL-IKYTDEATTQTSDSNGSLASAMP-STSRVYGAQALALNATALRLPAAPEH 271
L+SN+ +L + + + + N +L +P +++ Q L L L +
Sbjct: 99 LSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQDILNLY 158
Query: 272 QHPD 275
Q PD
Sbjct: 159 QEPD 162
>AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein.
Length = 1369
Score = 54.0 bits (124), Expect = 8e-07
Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 14 LALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV--------EX 65
L + + +++ S + L+ + +P L+ ++ HL L +N + P E
Sbjct: 280 LRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNEL 339
Query: 66 XXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRI 125
P + ++ L LN+S N L + +G + L+ F +
Sbjct: 340 QRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGN 399
Query: 126 GLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMT 184
L+ +P E+ + QL G NE IPE + L + L + N +ETL + +M
Sbjct: 400 FLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMP 459
Query: 185 ALVHCNLRNN 194
+ H +LR N
Sbjct: 460 HIKHVDLRLN 469
Score = 52.8 bits (121), Expect = 2e-06
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Query: 87 EIGNLKNLVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
E+ L +LNLS N L + + I L +L CN L+ +P +G + L TF
Sbjct: 338 ELQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVS-CN--ALRSVPAAVGVMHNLQTF 394
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-SS 202
GN L+++P E+ ++ +L +L L N+ +P+ ++++TA+ + N +E +
Sbjct: 395 LLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQA 454
Query: 203 ILKCKELMFLQLNSNQEHALI 223
+ K + + L N LI
Sbjct: 455 LRKMPHIKHVDLRLNVIRKLI 475
Score = 43.2 bits (97), Expect = 0.002
Identities = 25/100 (25%), Positives = 51/100 (51%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 554 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 613
Query: 183 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ V N LE P+ ++K L FL ++N+ +L
Sbjct: 614 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESL 653
Score = 36.7 bits (81), Expect = 0.13
Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 6/131 (4%)
Query: 127 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L+ P ++ KL +L+ GN+LK IP + + +++ + +N IE P+ M ++
Sbjct: 700 LQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCSRMHTVIAHSNCIEVFPEVM-QLPE 758
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMP 245
+ +L N L + +L L L N L D T + ++ P
Sbjct: 759 IKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL----DHKTLELLNNIRCFKIDQP 814
Query: 246 STSRVYGAQAL 256
ST GA A+
Sbjct: 815 STGDASGAPAV 825
>AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 154
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 130 IPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVH 188
+P+EI + + L+ N+L+ +PE+ L KLR L L +N+I+ LP + LV
Sbjct: 27 VPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE 86
Query: 189 CNLRNNRLEQFPSSILKCKELMFLQLNSN 217
++ N + + P SI CK L + N
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGN 115
Score = 48.4 bits (110), Expect = 4e-05
Identities = 24/89 (26%), Positives = 47/89 (52%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L+E+P++ +L +L G NE++ +P E+ + +L L + N+I +P+++ AL
Sbjct: 48 LRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKAL 107
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ N L + P S + + L L +N
Sbjct: 108 QVADFSGNPLTRLPESFPELQNLTCLSVN 136
Score = 45.6 bits (103), Expect = 3e-04
Identities = 28/98 (28%), Positives = 45/98 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
GN L +PE L L L++ + +++LP+ + +
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGK 149
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/116 (25%), Positives = 49/116 (42%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 152 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
IPE ++ L+ N + LP++ + L ++ + L+ P +I K K
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGKQK 151
Score = 41.1 bits (92), Expect = 0.006
Identities = 29/115 (25%), Positives = 45/115 (39%)
Query: 22 AKKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXX 81
A+ L L+ ++ E+P + +++ L L N+I P E
Sbjct: 35 ARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEI 94
Query: 82 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGK 136
P I K L + S NPL L +L+ L N I L+ +P+ IGK
Sbjct: 95 PEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGK 149
Score = 37.9 bits (84), Expect = 0.057
Identities = 29/128 (22%), Positives = 61/128 (47%), Gaps = 3/128 (2%)
Query: 140 LDTFGARGNELKTIPEEMTSLAK-LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQ 198
+++ R L +PEE+ A+ L L L+ NQ+ LP+ ++ L L +N +++
Sbjct: 14 VESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQR 73
Query: 199 FPSSILKCKELMFLQLNSNQEHALIKYTDEA-TTQTSDSNGSLASAMP-STSRVYGAQAL 256
P I +L+ L ++ N+ + + Q +D +G+ + +P S + L
Sbjct: 74 LPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCL 133
Query: 257 ALNATALR 264
++N +L+
Sbjct: 134 SVNDISLQ 141
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 52.0 bits (119), Expect = 3e-06
Identities = 44/139 (31%), Positives = 62/139 (44%), Gaps = 5/139 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDT 142
P+ L L L L N L L I G + L W + +P + L QL
Sbjct: 262 PSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQV 321
Query: 143 FGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTA-LVHCNLRNNRLEQFP 200
N++ I P L +LR L+L N ++ L + RM A L + +L+NNRL Q P
Sbjct: 322 LILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLP 381
Query: 201 SSIL-KCKELMFLQLNSNQ 218
+I LM +QL +NQ
Sbjct: 382 GNIFANVNGLMAIQLQNNQ 400
Score = 39.1 bits (87), Expect = 0.025
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 3/73 (4%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF-PSSIL 204
NEL I P +L LR+L+L NN+++ LP + +L L +N+L Q P+
Sbjct: 87 NELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFS 146
Query: 205 KCKELMFLQLNSN 217
+C L LQL+ N
Sbjct: 147 QCSNLKELQLHGN 159
Score = 34.3 bits (75), Expect = 0.70
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARG 147
NL+ L L LS N ++ + P L +L + L+++ + + L L +
Sbjct: 315 NLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQN 374
Query: 148 NELKTIPEEM-TSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNN 194
N L+ +P + ++ L + L+NNQ+E LP D + L L +N
Sbjct: 375 NRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDN 423
>AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/107 (23%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
G+ E + + L+++PKE+ + L+ N+++ +P+++ + LR L++ +
Sbjct: 57 GEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPD 116
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N + LP T+ + L ++ N +++FP +I CK L ++ + N
Sbjct: 117 NDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVN 163
Score = 48.4 bits (110), Expect = 4e-05
Identities = 33/117 (28%), Positives = 53/117 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 100 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 159
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
A N + +P+ T L L L L + +E LP R+ L LR N L+ P+
Sbjct: 160 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPN 216
Score = 47.6 bits (108), Expect = 7e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 148 NELKTIP 154
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Score = 39.9 bits (89), Expect = 0.014
Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 1/134 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 204 LKCKELMFLQLNSN 217
+ +L L+L N
Sbjct: 196 GRLVKLRILELREN 209
>AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/107 (23%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
G+ E + + L+++PKE+ + L+ N+++ +P+++ + LR L++ +
Sbjct: 57 GEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPD 116
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N + LP T+ + L ++ N +++FP +I CK L ++ + N
Sbjct: 117 NDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVN 163
Score = 48.4 bits (110), Expect = 4e-05
Identities = 33/117 (28%), Positives = 53/117 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 100 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 159
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
A N + +P+ T L L L L + +E LP R+ L LR N L+ P+
Sbjct: 160 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPN 216
Score = 47.6 bits (108), Expect = 7e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 148 NELKTIP 154
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Score = 39.9 bits (89), Expect = 0.014
Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 1/134 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 204 LKCKELMFLQLNSN 217
+ +L L+L N
Sbjct: 196 GRLVKLRILELREN 209
>AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 51.6 bits (118), Expect = 4e-06
Identities = 36/127 (28%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Query: 205 KCKELMF 211
+ F
Sbjct: 232 DLSLVKF 238
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
V NN+L P I + K+LM L ++ N+ AL
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITAL 203
Score = 42.7 bits (96), Expect = 0.002
Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 2/180 (1%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 210 MFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQALALNATALRLPAA 268
L + N L + + + D + + +P R + Q L L L+ P A
Sbjct: 214 RELNVRRNYLKVLPQELVDLSLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPA 273
Score = 36.3 bits (80), Expect = 0.17
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 127 LKEIPKEIGKLTQL-DTFGA--RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
LKE P+ L DT A N L +P E+ L L L +N I +P+ + +
Sbjct: 83 LKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNL 142
Query: 184 TALVHCNLRNNRLEQFPSSI 203
L + NL N+L P+ +
Sbjct: 143 QMLTYLNLSRNQLSALPACL 162
>AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/107 (23%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
G+ E + + L+++PKE+ + L+ N+++ +P+++ + LR L++ +
Sbjct: 57 GEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPD 116
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N + LP T+ + L ++ N +++FP +I CK L ++ + N
Sbjct: 117 NDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVN 163
Score = 48.4 bits (110), Expect = 4e-05
Identities = 33/117 (28%), Positives = 53/117 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 100 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 159
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
A N + +P+ T L L L L + +E LP R+ L LR N L+ P+
Sbjct: 160 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPN 216
Score = 47.6 bits (108), Expect = 7e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 148 NELKTIP 154
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Score = 39.9 bits (89), Expect = 0.014
Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 1/134 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 204 LKCKELMFLQLNSN 217
+ +L L+L N
Sbjct: 196 GRLVKLRILELREN 209
>AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 51.6 bits (118), Expect = 4e-06
Identities = 36/127 (28%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Query: 205 KCKELMF 211
+ F
Sbjct: 232 DLSLVKF 238
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
V NN+L P I + K+LM L ++ N+ AL
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITAL 203
Score = 42.7 bits (96), Expect = 0.002
Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 2/180 (1%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 210 MFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSR-VYGAQALALNATALRLPAA 268
L + N L + + + D + + +P R + Q L L L+ P A
Sbjct: 214 RELNVRRNYLKVLPQELVDLSLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPA 273
Score = 36.3 bits (80), Expect = 0.17
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 127 LKEIPKEIGKLTQL-DTFGA--RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
LKE P+ L DT A N L +P E+ L L L +N I +P+ + +
Sbjct: 83 LKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNL 142
Query: 184 TALVHCNLRNNRLEQFPSSI 203
L + NL N+L P+ +
Sbjct: 143 QMLTYLNLSRNQLSALPACL 162
>AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/107 (23%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
G+ E + + L+++PKE+ + L+ N+++ +P+++ + LR L++ +
Sbjct: 57 GEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPD 116
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N + LP T+ + L ++ N +++FP +I CK L ++ + N
Sbjct: 117 NDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVN 163
Score = 48.4 bits (110), Expect = 4e-05
Identities = 33/117 (28%), Positives = 53/117 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 100 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 159
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
A N + +P+ T L L L L + +E LP R+ L LR N L+ P+
Sbjct: 160 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPN 216
Score = 47.6 bits (108), Expect = 7e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 148 NELKTIP 154
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Score = 39.9 bits (89), Expect = 0.014
Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 1/134 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 204 LKCKELMFLQLNSN 217
+ +L L+L N
Sbjct: 196 GRLVKLRILELREN 209
>AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein
protein.
Length = 217
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/107 (23%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 112 GDLEKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLEN 170
G+ E + + L+++PKE+ + L+ N+++ +P+++ + LR L++ +
Sbjct: 57 GEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPD 116
Query: 171 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
N + LP T+ + L ++ N +++FP +I CK L ++ + N
Sbjct: 117 NDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVN 163
Score = 48.4 bits (110), Expect = 4e-05
Identities = 33/117 (28%), Positives = 53/117 (45%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P ++ N + L L++ N L+ L I L L+ ++ G++E P+ I L
Sbjct: 100 PKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIE 159
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 201
A N + +P+ T L L L L + +E LP R+ L LR N L+ P+
Sbjct: 160 ASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPN 216
Score = 47.6 bits (108), Expect = 7e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Query: 28 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE 87
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 88 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 147
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 148 NELKTIP 154
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Query: 97 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 155
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Score = 39.9 bits (89), Expect = 0.014
Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 1/134 (0%)
Query: 85 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 144 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 204 LKCKELMFLQLNSN 217
+ +L L+L N
Sbjct: 196 GRLVKLRILELREN 209
>BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein.
Length = 763
Score = 51.2 bits (117), Expect = 6e-06
Identities = 45/169 (26%), Positives = 70/169 (41%), Gaps = 2/169 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+ E+P L + +E L L+ N I V P P + L
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
V L S N L L EIG L++L + + +P++IG+L L R N LK +P
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLP 227
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
+E+ L +++ N++ +P M L L NN L+ P+ I
Sbjct: 228 QELVDLPLVKF-DFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 1/120 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
V NN+L P I + K+LM L ++ N+ AL
Sbjct: 169 VLI-ASNNKLGSLPEEIGQLKQLMELDVSCNEITAL 203
Score = 42.3 bits (95), Expect = 0.003
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 210 MFLQLNSN 217
L + N
Sbjct: 214 RELNVRRN 221
Score = 36.3 bits (80), Expect = 0.17
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 127 LKEIPKEIGKLTQL-DTFGA--RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
LKE P+ L DT A N L +P E+ L L L +N I +P+ + +
Sbjct: 83 LKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNL 142
Query: 184 TALVHCNLRNNRLEQFPSSI 203
L + NL N+L P+ +
Sbjct: 143 QMLTYLNLSRNQLSALPACL 162
>BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein.
Length = 696
Score = 51.2 bits (117), Expect = 6e-06
Identities = 45/169 (26%), Positives = 70/169 (41%), Gaps = 2/169 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+ E+P L + +E L L+ N I V P P + L
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
V L S N L L EIG L++L + + +P++IG+L L R N LK +P
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLP 227
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
+E+ L +++ N++ +P M L L NN L+ P+ I
Sbjct: 228 QELVDLPLVKF-DFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 1/120 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
V NN+L P I + K+LM L ++ N+ AL
Sbjct: 169 VLI-ASNNKLGSLPEEIGQLKQLMELDVSCNEITAL 203
Score = 42.3 bits (95), Expect = 0.003
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 210 MFLQLNSN 217
L + N
Sbjct: 214 RELNVRRN 221
Score = 36.3 bits (80), Expect = 0.17
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 127 LKEIPKEIGKLTQL-DTFGA--RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
LKE P+ L DT A N L +P E+ L L L +N I +P+ + +
Sbjct: 83 LKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNL 142
Query: 184 TALVHCNLRNNRLEQFPSSI 203
L + NL N+L P+ +
Sbjct: 143 QMLTYLNLSRNQLSALPACL 162
>AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isoform B
protein.
Length = 728
Score = 51.2 bits (117), Expect = 6e-06
Identities = 45/169 (26%), Positives = 70/169 (41%), Gaps = 2/169 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+ E+P L + +E L L+ N I V P P + L
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
V L S N L L EIG L++L + + +P++IG+L L R N LK +P
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLP 227
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
+E+ L +++ N++ +P M L L NN L+ P+ I
Sbjct: 228 QELVDLPLVKF-DFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 1/120 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
V NN+L P I + K+LM L ++ N+ AL
Sbjct: 169 VLI-ASNNKLGSLPEEIGQLKQLMELDVSCNEITAL 203
Score = 42.3 bits (95), Expect = 0.003
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 210 MFLQLNSN 217
L + N
Sbjct: 214 RELNVRRN 221
Score = 36.3 bits (80), Expect = 0.17
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 127 LKEIPKEIGKLTQL-DTFGA--RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
LKE P+ L DT A N L +P E+ L L L +N I +P+ + +
Sbjct: 83 LKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNL 142
Query: 184 TALVHCNLRNNRLEQFPSSI 203
L + NL N+L P+ +
Sbjct: 143 QMLTYLNLSRNQLSALPACL 162
>AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isoform a
protein.
Length = 696
Score = 51.2 bits (117), Expect = 6e-06
Identities = 45/169 (26%), Positives = 70/169 (41%), Gaps = 2/169 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+ E+P L + +E L L+ N I V P P + L
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
V L S N L L EIG L++L + + +P++IG+L L R N LK +P
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLP 227
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
+E+ L +++ N++ +P M L L NN L+ P+ I
Sbjct: 228 QELVDLPLVKF-DFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 1/120 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
V NN+L P I + K+LM L ++ N+ AL
Sbjct: 169 VLI-ASNNKLGSLPEEIGQLKQLMELDVSCNEITAL 203
Score = 42.3 bits (95), Expect = 0.003
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 210 MFLQLNSN 217
L + N
Sbjct: 214 RELNVRRN 221
Score = 36.3 bits (80), Expect = 0.17
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 127 LKEIPKEIGKLTQL-DTFGA--RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
LKE P+ L DT A N L +P E+ L L L +N I +P+ + +
Sbjct: 83 LKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNL 142
Query: 184 TALVHCNLRNNRLEQFPSSI 203
L + NL N+L P+ +
Sbjct: 143 QMLTYLNLSRNQLSALPACL 162
>AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein.
Length = 793
Score = 51.2 bits (117), Expect = 6e-06
Identities = 45/169 (26%), Positives = 70/169 (41%), Gaps = 2/169 (1%)
Query: 35 ITEIPGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 94
+ E+P L + +E L L+ N I V P P + L
Sbjct: 174 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 233
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
V L S N L L EIG L++L + + +P++IG+L L R N LK +P
Sbjct: 234 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLP 292
Query: 155 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 203
+E+ L +++ N++ +P M L L NN L+ P+ I
Sbjct: 293 QELVDLPLVKF-DFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 340
Score = 51.2 bits (117), Expect = 6e-06
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 1/120 (0%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 178 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 236
Query: 145 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 204
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 237 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 296
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 174 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 233
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
V NN+L P I + K+LM L ++ N+ AL
Sbjct: 234 VLI-ASNNKLGSLPEEIGQLKQLMELDVSCNEITAL 268
Score = 42.3 bits (95), Expect = 0.003
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 160 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 219
Query: 150 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 209
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 220 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 278
Query: 210 MFLQLNSN 217
L + N
Sbjct: 279 RELNVRRN 286
Score = 36.3 bits (80), Expect = 0.17
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 127 LKEIPKEIGKLTQL-DTFGA--RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 183
LKE P+ L DT A N L +P E+ L L L +N I +P+ + +
Sbjct: 148 LKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNL 207
Query: 184 TALVHCNLRNNRLEQFPSSI 203
L + NL N+L P+ +
Sbjct: 208 QMLTYLNLSRNQLSALPACL 227
>BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like family,
member 1 protein.
Length = 696
Score = 50.8 bits (116), Expect = 8e-06
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V+L++ N L+ ++P L+ ++ N +K K+ +G L L+
Sbjct: 75 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG-LDDLE 133
Query: 142 TFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N L+ I P L KL L L +N I TLP + + + H +LR NRL+ P
Sbjct: 134 YLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
Score = 33.5 bits (73), Expect = 1.2
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 91 LKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
L +L L +N L + P DL KLE N + +P + + + RGN
Sbjct: 129 LDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNR 188
Query: 150 LKTIP--EEMTSLAKLRWLTLENN 171
LKT+P E + + + + LE+N
Sbjct: 189 LKTLPYEEVLEQIPGIAEILLEDN 212
Score = 33.1 bits (72), Expect = 1.6
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 148 NELKTIP-EEMTSLAKLRWLTLENNQIET-LPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L T+ E+ L L +L +E N I+ LP T + M L L NN L P +
Sbjct: 433 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 492
Query: 206 CKELMFLQLNSN 217
L L L++N
Sbjct: 493 GVSLSKLSLHNN 504
Score = 31.1 bits (67), Expect = 6.5
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 3/112 (2%)
Query: 92 KNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
KNL+ L+L N + V +L L + + L + +E L L+ N
Sbjct: 399 KNLILLDLGNNNIATVENNSFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNA 458
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
++ I P ++ KLR L L NN + +LP + +L +L NN P
Sbjct: 459 IQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLP 510
>BC026112-1|AAH26112.1| 116|Homo sapiens hypothetical protein
LOC401387 protein.
Length = 116
Score = 50.8 bits (116), Expect = 8e-06
Identities = 27/83 (32%), Positives = 44/83 (53%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
++EIP+ IG+L L + A N++ +P + SL L+ L L N + LP + + +L
Sbjct: 14 IREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAICNIFSL 73
Query: 187 VHCNLRNNRLEQFPSSILKCKEL 209
N +N L + P I K K+L
Sbjct: 74 KEINFDDNPLLRPPVEICKGKQL 96
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/81 (30%), Positives = 35/81 (43%)
Query: 137 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
+TQL N ++ IP + L L L NNQI LP ++ + L NL N L
Sbjct: 1 MTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNL 60
Query: 197 EQFPSSILKCKELMFLQLNSN 217
PS+I L + + N
Sbjct: 61 TALPSAICNIFSLKEINFDDN 81
Score = 38.3 bits (85), Expect = 0.043
Identities = 19/63 (30%), Positives = 32/63 (50%)
Query: 160 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQE 219
+ +L+ L + NN I +P + + LV + NN++ P S+L +L L L+ N
Sbjct: 1 MTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNL 60
Query: 220 HAL 222
AL
Sbjct: 61 TAL 63
Score = 33.9 bits (74), Expect = 0.92
Identities = 17/83 (20%), Positives = 36/83 (43%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
+ L L++S N + + IG+L L + + +P + L L GN L
Sbjct: 1 MTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNL 60
Query: 151 KTIPEEMTSLAKLRWLTLENNQI 173
+P + ++ L+ + ++N +
Sbjct: 61 TALPSAICNIFSLKEINFDDNPL 83
>AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein.
Length = 696
Score = 50.8 bits (116), Expect = 8e-06
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V+L++ N L+ ++P L+ ++ N +K K+ +G L L+
Sbjct: 75 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG-LDDLE 133
Query: 142 TFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N L+ I P L KL L L +N I TLP + + + H +LR NRL+ P
Sbjct: 134 YLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
Score = 33.5 bits (73), Expect = 1.2
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 91 LKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
L +L L +N L + P DL KLE N + +P + + + RGN
Sbjct: 129 LDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNR 188
Query: 150 LKTIP--EEMTSLAKLRWLTLENN 171
LKT+P E + + + + LE+N
Sbjct: 189 LKTLPYEEVLEQIPGIAEILLEDN 212
Score = 33.1 bits (72), Expect = 1.6
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 148 NELKTIP-EEMTSLAKLRWLTLENNQIET-LPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L T+ E+ L L +L +E N I+ LP T + M L L NN L P +
Sbjct: 433 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 492
Query: 206 CKELMFLQLNSN 217
L L L++N
Sbjct: 493 GVSLSKLSLHNN 504
Score = 30.7 bits (66), Expect = 8.6
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 3/112 (2%)
Query: 92 KNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
KNL+ L+L N + V +L L + + L + +E L L+ N
Sbjct: 399 KNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNA 458
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
++ I P ++ KLR L L NN + +LP + +L +L NN P
Sbjct: 459 IQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLP 510
>AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like family,
member 1 protein.
Length = 696
Score = 50.8 bits (116), Expect = 8e-06
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V+L++ N L+ ++P L+ ++ N +K K+ +G L L+
Sbjct: 75 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG-LDDLE 133
Query: 142 TFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N L+ I P L KL L L +N I TLP + + + H +LR NRL+ P
Sbjct: 134 YLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
Score = 33.5 bits (73), Expect = 1.2
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 91 LKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
L +L L +N L + P DL KLE N + +P + + + RGN
Sbjct: 129 LDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNR 188
Query: 150 LKTIP--EEMTSLAKLRWLTLENN 171
LKT+P E + + + + LE+N
Sbjct: 189 LKTLPYEEVLEQIPGIAEILLEDN 212
Score = 33.1 bits (72), Expect = 1.6
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 148 NELKTIP-EEMTSLAKLRWLTLENNQIET-LPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L T+ E+ L L +L +E N I+ LP T + M L L NN L P +
Sbjct: 433 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 492
Query: 206 CKELMFLQLNSN 217
L L L++N
Sbjct: 493 GVSLSKLSLHNN 504
Score = 30.7 bits (66), Expect = 8.6
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 3/112 (2%)
Query: 92 KNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
KNL+ L+L N + V +L L + + L + +E L L+ N
Sbjct: 399 KNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNA 458
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
++ I P ++ KLR L L NN + +LP + +L +L NN P
Sbjct: 459 IQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLP 510
>AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein.
Length = 760
Score = 50.8 bits (116), Expect = 8e-06
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V+L++ N L+ ++P L+ ++ N +K K+ +G L L+
Sbjct: 139 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG-LDDLE 197
Query: 142 TFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N L+ I P L KL L L +N I TLP + + + H +LR NRL+ P
Sbjct: 198 YLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 257
Score = 33.5 bits (73), Expect = 1.2
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 91 LKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 149
L +L L +N L + P DL KLE N + +P + + + RGN
Sbjct: 193 LDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNR 252
Query: 150 LKTIP--EEMTSLAKLRWLTLENN 171
LKT+P E + + + + LE+N
Sbjct: 253 LKTLPYEEVLEQIPGIAEILLEDN 276
Score = 33.1 bits (72), Expect = 1.6
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 148 NELKTIP-EEMTSLAKLRWLTLENNQIET-LPDTMDRMTALVHCNLRNNRLEQFPSSILK 205
N L T+ E+ L L +L +E N I+ LP T + M L L NN L P +
Sbjct: 497 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 556
Query: 206 CKELMFLQLNSN 217
L L L++N
Sbjct: 557 GVSLSKLSLHNN 568
Score = 30.7 bits (66), Expect = 8.6
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 3/112 (2%)
Query: 92 KNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
KNL+ L+L N + V +L L + + L + +E L L+ N
Sbjct: 463 KNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNA 522
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
++ I P ++ KLR L L NN + +LP + +L +L NN P
Sbjct: 523 IQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLP 574
>U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Query: 92 KNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
K+L L LS N L+ L P + D+E L F +R L P + KL ++ N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Query: 150 LKTIPEE-MTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
LK+IP+ S + L L L+N +E D +T L H +L NNRL Q PS+
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 286
Score = 45.6 bits (103), Expect = 3e-04
Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 5/132 (3%)
Query: 91 LKNLVNLNLSYNPLNVL-IPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGN 148
LK L+ L LS+N + V+ DL +L + + + E+P+ + L L N
Sbjct: 98 LKQLIYLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNN 157
Query: 149 ELKTIPEEMTSLAK-LRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSIL-K 205
+++ + AK LRWL L N + +L P +D + L ++ N+L +PS+ L K
Sbjct: 158 KIRELRAGPFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSK 217
Query: 206 CKELMFLQLNSN 217
+ + L+L+ N
Sbjct: 218 LRVVEELKLSHN 229
>BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Query: 92 KNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
K+L L LS N L+ L P + D+E L F +R L P + KL ++ N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Query: 150 LKTIPEE-MTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
LK+IP+ S + L L L+N +E D +T L H +L NNRL Q PS+
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 286
Score = 47.2 bits (107), Expect = 9e-05
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 5/132 (3%)
Query: 91 LKNLVNLNLSYNPLNVL-IPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGN 148
LK L+ L LS+N + VL DL +L + + + E+P+ + L L N
Sbjct: 98 LKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNN 157
Query: 149 ELKTIPEEMTSLAK-LRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSIL-K 205
+++ + AK LRWL L N + +L P +D + L ++ N+L +PS+ L K
Sbjct: 158 KIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSK 217
Query: 206 CKELMFLQLNSN 217
+ + L+L+ N
Sbjct: 218 LRVVEELKLSHN 229
>BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Query: 92 KNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
K+L L LS N L+ L P + D+E L F +R L P + KL ++ N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Query: 150 LKTIPEE-MTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
LK+IP+ S + L L L+N +E D +T L H +L NNRL Q PS+
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 286
Score = 47.2 bits (107), Expect = 9e-05
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 5/132 (3%)
Query: 91 LKNLVNLNLSYNPLNVL-IPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGN 148
LK L+ L LS+N + VL DL +L + + + E+P+ + L L N
Sbjct: 98 LKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNN 157
Query: 149 ELKTIPEEMTSLAK-LRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSIL-K 205
+++ + AK LRWL L N + +L P +D + L ++ N+L +PS+ L K
Sbjct: 158 KIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSK 217
Query: 206 CKELMFLQLNSN 217
+ + L+L+ N
Sbjct: 218 LRVVEELKLSHN 229
>AK127177-1|BAC86870.1| 279|Homo sapiens protein ( Homo sapiens
cDNA FLJ45242 fis, clone BRCOC2006639. ).
Length = 279
Score = 50.4 bits (115), Expect = 1e-05
Identities = 23/85 (27%), Positives = 48/85 (56%)
Query: 133 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 192
E+G L +L T N L T+PE + L++LT++ N++ +P + ++ +L ++
Sbjct: 41 EVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMA 100
Query: 193 NNRLEQFPSSILKCKELMFLQLNSN 217
NRL P + + +EL ++ +++N
Sbjct: 101 GNRLAFLPLDLGRSRELQYVYVDNN 125
Score = 40.7 bits (91), Expect = 0.008
Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 146
E+G+LK L L++S N L L + L+ +R L +P+ + +L L+
Sbjct: 41 EVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMA 100
Query: 147 GNELKTIPEEMTSLAKLRWLTLENN-QIETLP 177
GN L +P ++ +L+++ ++NN ++ LP
Sbjct: 101 GNRLAFLPLDLGRSRELQYVYVDNNIHLKGLP 132
Score = 40.3 bits (90), Expect = 0.011
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Query: 106 VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRW 165
+L+ E+GDL++L+ + L +P+ + L N L +P + L L
Sbjct: 37 ILVVEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNE 96
Query: 166 LTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPS 201
L++ N++ LP + R L + + NN L+ PS
Sbjct: 97 LSMAGNRLAFLPLDLGRSRELQYVYVDNNIHLKGLPS 133
>AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 50.4 bits (115), Expect = 1e-05
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Query: 92 KNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
K+L L LS N L+ L P + D+E L F +R L P + KL ++ N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Query: 150 LKTIPEE-MTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
LK+IP+ S + L L L+N +E D +T L H +L NNRL Q PS+
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 286
Score = 47.2 bits (107), Expect = 9e-05
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 5/132 (3%)
Query: 91 LKNLVNLNLSYNPLNVL-IPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGN 148
LK L+ L LS+N + VL DL +L + + + E+P+ + L L N
Sbjct: 98 LKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNN 157
Query: 149 ELKTIPEEMTSLAK-LRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSIL-K 205
+++ + AK LRWL L N + +L P +D + L ++ N+L +PS+ L K
Sbjct: 158 KIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSK 217
Query: 206 CKELMFLQLNSN 217
+ + L+L+ N
Sbjct: 218 LRVVEELKLSHN 229
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 48.8 bits (111), Expect = 3e-05
Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 85 PTE-IGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLD 141
PTE + NL++L +L L N ++ + P L L W + L EIP + + L+ L
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 199
N++ IP+ +L+ L L NN+I +L D + +L +L N L++F
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 200 PSSILKCKELMFLQLNSN 217
P++I L L +SN
Sbjct: 250 PTAIRTLSNLKELGFHSN 267
Score = 42.7 bits (96), Expect = 0.002
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 6/155 (3%)
Query: 8 IRENHILALIEQAIAKKKS--RLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKISVFPVE 64
++ N + + +A+ +S L L+ I+ +P ++ L + HL+L N ++ PV+
Sbjct: 121 LQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQ 180
Query: 65 XXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFW 121
+ GNL + V L+L N ++ L + D L LE
Sbjct: 181 AFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLD 240
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
N L E P I L+ L G N +++IPE+
Sbjct: 241 LNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEK 275
Score = 37.9 bits (84), Expect = 0.057
Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 8/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE---IGDLEKLEA-FWCNRIGLKEIPKEIGKLTQL 140
PT I L NL L N + IPE +G+ + F+ N I L +L
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRS-IPEKAFVGNPSLITIHFYDNPIQFVG-RSAFQHLPEL 307
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQF 199
T G T ++T A L LTL QI +LP T+ +++ L +L N LE
Sbjct: 308 RTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 367
Query: 200 PSSILKCKELMFLQLNSNQ 218
PS + C++L + L N+
Sbjct: 368 PSFSV-CQKLQKIDLRHNE 385
Score = 34.7 bits (76), Expect = 0.53
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 130 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 187
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 188 HCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
L N + P S L L L+ N
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDN 172
>BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 48.4 bits (110), Expect = 4e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Query: 87 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 143
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 83 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 141
Query: 144 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 200
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 201
Query: 201 SSILKCKELMFLQLNSNQ 218
+ ++ LQL N+
Sbjct: 202 GFLEHIGRILDLQLEDNK 219
Score = 38.7 bits (86), Expect = 0.032
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNN 194
LT+L GN L + + M L L +L LE N I E LP T + M L L NN
Sbjct: 410 LTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNN 469
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+ P I L + L +NQ
Sbjct: 470 LLQVLPPHIFSGVPLTKVNLKTNQ 493
Score = 33.9 bits (74), Expect = 0.92
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 97 LNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELKTI- 153
L+L N + VL +L +L+ + N L ++ K + L L+ N +K I
Sbjct: 392 LHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEIL 451
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-SSILKCKELM 210
P + KL+ L L NN ++ LP + L NL+ N+ P S+IL +L+
Sbjct: 452 PGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLL 509
>BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 48.4 bits (110), Expect = 4e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Query: 87 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 143
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 83 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 141
Query: 144 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 200
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 201
Query: 201 SSILKCKELMFLQLNSNQ 218
+ ++ LQL N+
Sbjct: 202 GFLEHIGRILDLQLEDNK 219
Score = 38.7 bits (86), Expect = 0.032
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNN 194
LT+L GN L + + M L L +L LE N I E LP T + M L L NN
Sbjct: 410 LTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNN 469
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+ P I L + L +NQ
Sbjct: 470 LLQVLPPHIFSGVPLTKVNLKTNQ 493
Score = 33.9 bits (74), Expect = 0.92
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 97 LNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELKTI- 153
L+L N + VL +L +L+ + N L ++ K + L L+ N +K I
Sbjct: 392 LHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEIL 451
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-SSILKCKELM 210
P + KL+ L L NN ++ LP + L NL+ N+ P S+IL +L+
Sbjct: 452 PGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLL 509
>BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 48.4 bits (110), Expect = 4e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Query: 87 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 143
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 83 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 141
Query: 144 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 200
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 201
Query: 201 SSILKCKELMFLQLNSNQ 218
+ ++ LQL N+
Sbjct: 202 GFLEHIGRILDLQLEDNK 219
Score = 38.7 bits (86), Expect = 0.032
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNN 194
LT+L GN L + + M L L +L LE N I E LP T + M L L NN
Sbjct: 410 LTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNN 469
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+ P I L + L +NQ
Sbjct: 470 LLQVLPPHIFSGVPLTKVNLKTNQ 493
Score = 33.9 bits (74), Expect = 0.92
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 97 LNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELKTI- 153
L+L N + VL +L +L+ + N L ++ K + L L+ N +K I
Sbjct: 392 LHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEIL 451
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-SSILKCKELM 210
P + KL+ L L NN ++ LP + L NL+ N+ P S+IL +L+
Sbjct: 452 PGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLL 509
>BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 48.4 bits (110), Expect = 4e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Query: 87 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 143
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 83 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 141
Query: 144 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 200
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 201
Query: 201 SSILKCKELMFLQLNSNQ 218
+ ++ LQL N+
Sbjct: 202 GFLEHIGRILDLQLEDNK 219
Score = 38.7 bits (86), Expect = 0.032
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 137 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNN 194
LT+L GN L + + M L L +L LE N I E LP T + M L L NN
Sbjct: 410 LTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNN 469
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ 218
L+ P I L + L +NQ
Sbjct: 470 LLQVLPPHIFSGVPLTKVNLKTNQ 493
Score = 33.9 bits (74), Expect = 0.92
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 97 LNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELKTI- 153
L+L N + VL +L +L+ + N L ++ K + L L+ N +K I
Sbjct: 392 LHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEIL 451
Query: 154 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-SSILKCKELM 210
P + KL+ L L NN ++ LP + L NL+ N+ P S+IL +L+
Sbjct: 452 PGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLL 509
>AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22774 fis, clone KAIA1575. ).
Length = 440
Score = 48.4 bits (110), Expect = 4e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Query: 87 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 143
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 40 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 98
Query: 144 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 200
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 99 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 158
Query: 201 SSILKCKELMFLQLNSNQ 218
+ ++ LQL N+
Sbjct: 159 GFLEHIGRILDLQLEDNK 176
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 47.6 bits (108), Expect = 7e-05
Identities = 55/203 (27%), Positives = 87/203 (42%), Gaps = 11/203 (5%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX-P 85
LS+N +TE+ PGL + +E L L N +S P + P
Sbjct: 21 LSMNN--LTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 78
Query: 86 TE-IGNLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLD 141
E + L +L +L L N ++ L+PE L L W + L EIP + + L L
Sbjct: 79 AEALWELPSLQSLRLDANLIS-LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 199
N + IP+ +L L L L NN+I+ L + + + L +L N+L++F
Sbjct: 138 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF 197
Query: 200 PSSILKCKELMFLQLNSNQEHAL 222
P +I L L ++N A+
Sbjct: 198 PVAIRTLGRLQELGFHNNNIKAI 220
Score = 38.3 bits (85), Expect = 0.043
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
L L L LS+N + L P + +KLE + EI + +L+ L N
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNA 357
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+++I PE ++L L L L +NQ+ TLP + + L+H L+ N
Sbjct: 358 IRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKLKGN 401
Score = 34.7 bits (76), Expect = 0.53
Identities = 30/112 (26%), Positives = 42/112 (37%), Gaps = 3/112 (2%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG--NLKNLVNLNLSYNPLN 105
+ HL+L N ++ PV + NL +LV L+L N +
Sbjct: 112 LRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 171
Query: 106 VL-IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
L L LE N L+E P I L +L G N +K IPE+
Sbjct: 172 HLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEK 223
Score = 33.5 bits (73), Expect = 1.2
Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 8/154 (5%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLN 105
+E L L+ NK+ FPV P + +GN L ++ NP+
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGN-PLLQTIHFYDNPIQ 242
Query: 106 VLIPEIGD-LEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAK 162
+ L KL N + ++E P ++ T L+ ++ +P M L +
Sbjct: 243 FVGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPR 301
Query: 163 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
LR L L +NQIE LP ++ R L L++NR+
Sbjct: 302 LRVLELSHNQIEELP-SLHRCQKLEEIGLQHNRI 334
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 47.6 bits (108), Expect = 7e-05
Identities = 55/203 (27%), Positives = 87/203 (42%), Gaps = 11/203 (5%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX-P 85
LS+N +TE+ PGL + +E L L N +S P + P
Sbjct: 21 LSMNN--LTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 78
Query: 86 TE-IGNLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLD 141
E + L +L +L L N ++ L+PE L L W + L EIP + + L L
Sbjct: 79 AEALWELPSLQSLRLDANLIS-LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 199
N + IP+ +L L L L NN+I+ L + + + L +L N+L++F
Sbjct: 138 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF 197
Query: 200 PSSILKCKELMFLQLNSNQEHAL 222
P +I L L ++N A+
Sbjct: 198 PVAIRTLGRLQELGFHNNNIKAI 220
Score = 38.3 bits (85), Expect = 0.043
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
L L L LS+N + L P + +KLE + EI + +L+ L N
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNA 357
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+++I PE ++L L L L +NQ+ TLP + + L+H L+ N
Sbjct: 358 IRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKLKGN 401
Score = 34.7 bits (76), Expect = 0.53
Identities = 30/112 (26%), Positives = 42/112 (37%), Gaps = 3/112 (2%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG--NLKNLVNLNLSYNPLN 105
+ HL+L N ++ PV + NL +LV L+L N +
Sbjct: 112 LRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 171
Query: 106 VL-IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
L L LE N L+E P I L +L G N +K IPE+
Sbjct: 172 HLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEK 223
Score = 33.5 bits (73), Expect = 1.2
Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 8/154 (5%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLN 105
+E L L+ NK+ FPV P + +GN L ++ NP+
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGN-PLLQTIHFYDNPIQ 242
Query: 106 VLIPEIGD-LEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAK 162
+ L KL N + ++E P ++ T L+ ++ +P M L +
Sbjct: 243 FVGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPR 301
Query: 163 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
LR L L +NQIE LP ++ R L L++NR+
Sbjct: 302 LRVLELSHNQIEELP-SLHRCQKLEEIGLQHNRI 334
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 47.6 bits (108), Expect = 7e-05
Identities = 55/203 (27%), Positives = 87/203 (42%), Gaps = 11/203 (5%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX-P 85
LS+N +TE+ PGL + +E L L N +S P + P
Sbjct: 21 LSMNN--LTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 78
Query: 86 TE-IGNLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLD 141
E + L +L +L L N ++ L+PE L L W + L EIP + + L L
Sbjct: 79 AEALWELPSLQSLRLDANLIS-LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 199
N + IP+ +L L L L NN+I+ L + + + L +L N+L++F
Sbjct: 138 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF 197
Query: 200 PSSILKCKELMFLQLNSNQEHAL 222
P +I L L ++N A+
Sbjct: 198 PVAIRTLGRLQELGFHNNNIKAI 220
Score = 38.3 bits (85), Expect = 0.043
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
L L L LS+N + L P + +KLE + EI + +L+ L N
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNA 357
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+++I PE ++L L L L +NQ+ TLP + + L+H L+ N
Sbjct: 358 IRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKLKGN 401
Score = 34.7 bits (76), Expect = 0.53
Identities = 30/112 (26%), Positives = 42/112 (37%), Gaps = 3/112 (2%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG--NLKNLVNLNLSYNPLN 105
+ HL+L N ++ PV + NL +LV L+L N +
Sbjct: 112 LRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 171
Query: 106 VL-IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
L L LE N L+E P I L +L G N +K IPE+
Sbjct: 172 HLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEK 223
Score = 33.5 bits (73), Expect = 1.2
Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 8/154 (5%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLN 105
+E L L+ NK+ FPV P + +GN L ++ NP+
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGN-PLLQTIHFYDNPIQ 242
Query: 106 VLIPEIGD-LEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAK 162
+ L KL N + ++E P ++ T L+ ++ +P M L +
Sbjct: 243 FVGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPR 301
Query: 163 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
LR L L +NQIE LP ++ R L L++NR+
Sbjct: 302 LRVLELSHNQIEELP-SLHRCQKLEEIGLQHNRI 334
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 47.6 bits (108), Expect = 7e-05
Identities = 55/203 (27%), Positives = 87/203 (42%), Gaps = 11/203 (5%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX-P 85
LS+N +TE+ PGL + +E L L N +S P + P
Sbjct: 73 LSMNN--LTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 130
Query: 86 TE-IGNLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLD 141
E + L +L +L L N ++ L+PE L L W + L EIP + + L L
Sbjct: 131 AEALWELPSLQSLRLDANLIS-LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 189
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 199
N + IP+ +L L L L NN+I+ L + + + L +L N+L++F
Sbjct: 190 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF 249
Query: 200 PSSILKCKELMFLQLNSNQEHAL 222
P +I L L ++N A+
Sbjct: 250 PVAIRTLGRLQELGFHNNNIKAI 272
Score = 38.3 bits (85), Expect = 0.043
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
L L L LS+N + L P + +KLE + EI + +L+ L N
Sbjct: 351 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNA 409
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+++I PE ++L L L L +NQ+ TLP + + L+H L+ N
Sbjct: 410 IRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKLKGN 453
Score = 34.7 bits (76), Expect = 0.53
Identities = 30/112 (26%), Positives = 42/112 (37%), Gaps = 3/112 (2%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG--NLKNLVNLNLSYNPLN 105
+ HL+L N ++ PV + NL +LV L+L N +
Sbjct: 164 LRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 223
Query: 106 VL-IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
L L LE N L+E P I L +L G N +K IPE+
Sbjct: 224 HLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEK 275
Score = 33.5 bits (73), Expect = 1.2
Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 8/154 (5%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLN 105
+E L L+ NK+ FPV P + +GN L ++ NP+
Sbjct: 236 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGN-PLLQTIHFYDNPIQ 294
Query: 106 VLIPEIGD-LEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAK 162
+ L KL N + ++E P ++ T L+ ++ +P M L +
Sbjct: 295 FVGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPR 353
Query: 163 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
LR L L +NQIE LP ++ R L L++NR+
Sbjct: 354 LRVLELSHNQIEELP-SLHRCQKLEEIGLQHNRI 386
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 47.6 bits (108), Expect = 7e-05
Identities = 55/203 (27%), Positives = 87/203 (42%), Gaps = 11/203 (5%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXX-P 85
LS+N +TE+ PGL + +E L L N +S P + P
Sbjct: 34 LSMNN--LTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 91
Query: 86 TE-IGNLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLD 141
E + L +L +L L N ++ L+PE L L W + L EIP + + L L
Sbjct: 92 AEALWELPSLQSLRLDANLIS-LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 150
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 199
N + IP+ +L L L L NN+I+ L + + + L +L N+L++F
Sbjct: 151 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF 210
Query: 200 PSSILKCKELMFLQLNSNQEHAL 222
P +I L L ++N A+
Sbjct: 211 PVAIRTLGRLQELGFHNNNIKAI 233
Score = 38.3 bits (85), Expect = 0.043
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 149
L L L LS+N + L P + +KLE + EI + +L+ L N
Sbjct: 312 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNA 370
Query: 150 LKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN 194
+++I PE ++L L L L +NQ+ TLP + + L+H L+ N
Sbjct: 371 IRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKLKGN 414
Score = 34.7 bits (76), Expect = 0.53
Identities = 30/112 (26%), Positives = 42/112 (37%), Gaps = 3/112 (2%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTEIG--NLKNLVNLNLSYNPLN 105
+ HL+L N ++ PV + NL +LV L+L N +
Sbjct: 125 LRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 184
Query: 106 VL-IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
L L LE N L+E P I L +L G N +K IPE+
Sbjct: 185 HLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEK 236
Score = 33.5 bits (73), Expect = 1.2
Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 8/154 (5%)
Query: 48 VEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLN 105
+E L L+ NK+ FPV P + +GN L ++ NP+
Sbjct: 197 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGN-PLLQTIHFYDNPIQ 255
Query: 106 VLIPEIGD-LEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAK 162
+ L KL N + ++E P ++ T L+ ++ +P M L +
Sbjct: 256 FVGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPR 314
Query: 163 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
LR L L +NQIE LP ++ R L L++NR+
Sbjct: 315 LRVLELSHNQIEELP-SLHRCQKLEEIGLQHNRI 347
>AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens
cDNA FLJ25459 fis, clone TST09038. ).
Length = 475
Score = 46.8 bits (106), Expect = 1e-04
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 107 LIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWL 166
L + L L A N L IP +I KL L N+L+++P E+ ++ LR L
Sbjct: 48 LSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLREL 107
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRL--EQFP 200
L NN + LP + R+ L++ L N + EQ P
Sbjct: 108 LLNNNLLRVLPYELGRLFQLLNFMLDNLAVHPEQLP 143
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 144
P +I L NLV L+LS N L L E+G++ L N L+ +P E+G+L QL F
Sbjct: 72 PPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPYELGRLFQLLNFM 131
Query: 145 ARGNELKTIPEEMTSLAKLRWLTL-ENNQI 173
+ L PE+ L W+TL E +QI
Sbjct: 132 L--DNLAVHPEQ---LPPRPWITLKERDQI 156
Score = 42.7 bits (96), Expect = 0.002
Identities = 24/94 (25%), Positives = 43/94 (45%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 186
++ + + LT L N L IP ++ L L +L L +N++ +LP + M +L
Sbjct: 45 VRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSL 104
Query: 187 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEH 220
L NN L P + + +L+ L++ H
Sbjct: 105 RELLLNNNLLRVLPYELGRLFQLLNFMLDNLAVH 138
Score = 39.1 bits (87), Expect = 0.025
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 145
T + +L +L L+L+ N L+ + P+I L L + L+ +P E+G + L
Sbjct: 50 TSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLL 109
Query: 146 RGNELKTIPEEMTSLAKLRWLTLENNQI--ETLP 177
N L+ +P E+ L +L L+N + E LP
Sbjct: 110 NNNLLRVLPYELGRLFQLLNFMLDNLAVHPEQLP 143
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 46/175 (26%), Positives = 68/175 (38%), Gaps = 8/175 (4%)
Query: 97 LNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGARGNELKTIP 154
L+L +N + + P L L N +K IP L L NE+++I
Sbjct: 84 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 143
Query: 155 EE-MTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMF 211
+ LA L L L NQIETL PD+ + L L NNR+ P + + +
Sbjct: 144 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 203
Query: 212 LQLNSNQEHA---LIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALALNATAL 263
L+L+SN H ++ D T N A+ R+ G + L
Sbjct: 204 LRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEEL 258
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 46.4 bits (105), Expect = 2e-04
Identities = 46/175 (26%), Positives = 68/175 (38%), Gaps = 8/175 (4%)
Query: 97 LNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGARGNELKTIP 154
L+L +N + + P L L N +K IP L L NE+++I
Sbjct: 62 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 121
Query: 155 EE-MTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMF 211
+ LA L L L NQIETL PD+ + L L NNR+ P + + +
Sbjct: 122 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 181
Query: 212 LQLNSNQEHA---LIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALALNATAL 263
L+L+SN H ++ D T N A+ R+ G + L
Sbjct: 182 LRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEEL 236
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 46/175 (26%), Positives = 68/175 (38%), Gaps = 8/175 (4%)
Query: 97 LNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGARGNELKTIP 154
L+L +N + + P L L N +K IP L L NE+++I
Sbjct: 84 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 143
Query: 155 EE-MTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMF 211
+ LA L L L NQIETL PD+ + L L NNR+ P + + +
Sbjct: 144 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 203
Query: 212 LQLNSNQEHA---LIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALALNATAL 263
L+L+SN H ++ D T N A+ R+ G + L
Sbjct: 204 LRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEEL 258
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 92 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 149
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 200
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 150 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 201 SSILKCKELMFLQLNSNQEHALIKYTDEATTQ 232
+ K +L L+LN N+ IK D T Q
Sbjct: 209 PKMFKLPQLQHLELNRNK----IKNVDGLTFQ 236
Score = 37.5 bits (83), Expect = 0.075
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 122 CNRIGLKEIPKEIGK-LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
C+R L +P+ + + +LD R + +K M+ L LR + L NN++ET+P+
Sbjct: 60 CSRKRLARLPEPLPSWVARLDLSHNRLSFIKA--SSMSHLQSLREVKLNNNELETIPNLG 117
Query: 181 DRMTALVHCNLRNNRL-EQFPSSILKCKELMFLQLNSN 217
+ +L NR+ E P + + + L L L+SN
Sbjct: 118 PVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN 155
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 92 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 149
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 200
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 150 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 201 SSILKCKELMFLQLNSNQEHALIKYTDEATTQ 232
+ K +L L+LN N+ IK D T Q
Sbjct: 209 PKMFKLPQLQHLELNRNK----IKNVDGLTFQ 236
Score = 37.5 bits (83), Expect = 0.075
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 122 CNRIGLKEIPKEIGK-LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
C+R L +P+ + + +LD R + +K M+ L LR + L NN++ET+P+
Sbjct: 60 CSRKRLARLPEPLPSWVARLDLSHNRLSFIKA--SSMSHLQSLREVKLNNNELETIPNLG 117
Query: 181 DRMTALVHCNLRNNRL-EQFPSSILKCKELMFLQLNSN 217
+ +L NR+ E P + + + L L L+SN
Sbjct: 118 PVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN 155
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 92 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 149
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 200
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 150 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 201 SSILKCKELMFLQLNSNQEHALIKYTDEATTQ 232
+ K +L L+LN N+ IK D T Q
Sbjct: 209 PKMFKLPQLQHLELNRNK----IKNVDGLTFQ 236
Score = 37.5 bits (83), Expect = 0.075
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 122 CNRIGLKEIPKEIGK-LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
C+R L +P+ + + +LD R + +K M+ L LR + L NN++ET+P+
Sbjct: 60 CSRKRLARLPEPLPSWVARLDLSHNRLSFIKA--SSMSHLQSLREVKLNNNELETIPNLG 117
Query: 181 DRMTALVHCNLRNNRL-EQFPSSILKCKELMFLQLNSN 217
+ +L NR+ E P + + + L L L+SN
Sbjct: 118 PVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN 155
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 32 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 89
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 200
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 90 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 148
Query: 201 SSILKCKELMFLQLNSNQEHALIKYTDEATTQ 232
+ K +L L+LN N+ IK D T Q
Sbjct: 149 PKMFKLPQLQHLELNRNK----IKNVDGLTFQ 176
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/152 (25%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 142
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 92 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 149
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 200
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 150 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 201 SSILKCKELMFLQLNSNQEHALIKYTDEATTQ 232
+ K +L L+LN N+ IK D T Q
Sbjct: 209 PKMFKLPQLQHLELNRNK----IKNVDGLTFQ 236
Score = 37.5 bits (83), Expect = 0.075
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 122 CNRIGLKEIPKEIGK-LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 180
C+R L +P+ + + +LD R + +K M+ L LR + L NN++ET+P+
Sbjct: 60 CSRKRLARLPEPLPSWVARLDLSHNRLSFIKA--SSMSHLQSLREVKLNNNELETIPNLG 117
Query: 181 DRMTALVHCNLRNNRL-EQFPSSILKCKELMFLQLNSN 217
+ +L NR+ E P + + + L L L+SN
Sbjct: 118 PVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN 155
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 45.2 bits (102), Expect = 4e-04
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 180
C+ GLK +PK I + + GN+ +P+E+++ L + L NN+I TL + +
Sbjct: 740 CSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSF 797
Query: 181 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
MT L+ L NRL P K L L L+ N
Sbjct: 798 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGN 835
Score = 41.9 bits (94), Expect = 0.003
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQI-ETLPDT 179
C GL EIP + + + N +K IP S KLR + L NNQI E PD
Sbjct: 286 CRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA 343
Query: 180 MDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQEHAL 222
+ +L L N++ + P S+ + L L LN+N+ + L
Sbjct: 344 FQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCL 387
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 45.2 bits (102), Expect = 4e-04
Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 6/155 (3%)
Query: 8 IRENHILALIEQAIAKKKS--RLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKISVFPVE 64
++ N + + +A+ +S L L+ I+ +P ++ L + HL+L N ++ PV+
Sbjct: 121 LQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQ 180
Query: 65 XXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFW 121
+ GNL +LV L+L N ++ L + D L LE
Sbjct: 181 AFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLD 240
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
N L E P I L+ L G N +++IPE+
Sbjct: 241 LNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEK 275
Score = 37.9 bits (84), Expect = 0.057
Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 8/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE---IGDLEKLEA-FWCNRIGLKEIPKEIGKLTQL 140
PT I L NL L N + IPE +G+ + F+ N I L +L
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRS-IPEKAFVGNPSLITIHFYDNPIQFVG-RSAFQHLPEL 307
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQF 199
T G T ++T A L LTL QI +LP T+ +++ L +L N LE
Sbjct: 308 RTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 367
Query: 200 PSSILKCKELMFLQLNSNQ 218
PS + C++L + L N+
Sbjct: 368 PSFSV-CQKLQKIDLRHNE 385
Score = 35.1 bits (77), Expect = 0.40
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 130 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 187
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 188 HCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
L N + P S L L L+ N
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDN 172
Score = 30.7 bits (66), Expect = 8.6
Identities = 37/164 (22%), Positives = 71/164 (43%), Gaps = 7/164 (4%)
Query: 90 NLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGAR 146
+L L + L+ N ++ IP+ G+L L + + + K+ L L+T
Sbjct: 184 SLSALQAMTLALNKIHH-IPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSSILK 205
N L P + +L+ L+ L +N I ++P+ +L+ + +N ++ S +
Sbjct: 243 YNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQ 302
Query: 206 -CKELMFLQLN-SNQEHALIKYTDEATTQTSDSNGSLASAMPST 247
EL L LN ++Q T A ++ G+ S++P T
Sbjct: 303 HLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQT 346
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 45.2 bits (102), Expect = 4e-04
Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 6/155 (3%)
Query: 8 IRENHILALIEQAIAKKKS--RLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKISVFPVE 64
++ N + + +A+ +S L L+ I+ +P ++ L + HL+L N ++ PV+
Sbjct: 121 LQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQ 180
Query: 65 XXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFW 121
+ GNL +LV L+L N ++ L + D L LE
Sbjct: 181 AFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLD 240
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
N L E P I L+ L G N +++IPE+
Sbjct: 241 LNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEK 275
Score = 37.9 bits (84), Expect = 0.057
Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 8/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE---IGDLEKLEA-FWCNRIGLKEIPKEIGKLTQL 140
PT I L NL L N + IPE +G+ + F+ N I L +L
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRS-IPEKAFVGNPSLITIHFYDNPIQFVG-RSAFQHLPEL 307
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQF 199
T G T ++T A L LTL QI +LP T+ +++ L +L N LE
Sbjct: 308 RTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 367
Query: 200 PSSILKCKELMFLQLNSNQ 218
PS + C++L + L N+
Sbjct: 368 PSFSV-CQKLQKIDLRHNE 385
Score = 35.1 bits (77), Expect = 0.40
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 130 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 187
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 188 HCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
L N + P S L L L+ N
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDN 172
Score = 30.7 bits (66), Expect = 8.6
Identities = 37/164 (22%), Positives = 71/164 (43%), Gaps = 7/164 (4%)
Query: 90 NLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGAR 146
+L L + L+ N ++ IP+ G+L L + + + K+ L L+T
Sbjct: 184 SLSALQAMTLALNKIHH-IPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSSILK 205
N L P + +L+ L+ L +N I ++P+ +L+ + +N ++ S +
Sbjct: 243 YNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQ 302
Query: 206 -CKELMFLQLN-SNQEHALIKYTDEATTQTSDSNGSLASAMPST 247
EL L LN ++Q T A ++ G+ S++P T
Sbjct: 303 HLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQT 346
>BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 45.2 bits (102), Expect = 4e-04
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 4/116 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLE-KLEAFWCNRIGLKEIPKEI---GKLTQL 140
P E L L +LNLS N L L ++ +L++ L P E+ G L L
Sbjct: 122 PAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLL 181
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
A N L+ + ++ LA L+ L L NNQ+ +P + L N R N+L
Sbjct: 182 SELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKL 237
Score = 32.7 bits (71), Expect = 2.1
Identities = 21/63 (33%), Positives = 29/63 (46%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
G L L L + N L L P+I L L+ + L EIP E+ +L RGN
Sbjct: 176 GALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGN 235
Query: 149 ELK 151
+L+
Sbjct: 236 KLR 238
>AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 45.2 bits (102), Expect = 4e-04
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 4/116 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLE-KLEAFWCNRIGLKEIPKEI---GKLTQL 140
P E L L +LNLS N L L ++ +L++ L P E+ G L L
Sbjct: 122 PAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLL 181
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 196
A N L+ + ++ LA L+ L L NNQ+ +P + L N R N+L
Sbjct: 182 SELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKL 237
Score = 32.7 bits (71), Expect = 2.1
Identities = 21/63 (33%), Positives = 29/63 (46%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 148
G L L L + N L L P+I L L+ + L EIP E+ +L RGN
Sbjct: 176 GALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGN 235
Query: 149 ELK 151
+L+
Sbjct: 236 KLR 238
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 45.2 bits (102), Expect = 4e-04
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 180
C+ GLK +PK I + + GN+ +P+E+++ L + L NN+I TL + +
Sbjct: 736 CSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSF 793
Query: 181 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
MT L+ L NRL P K L L L+ N
Sbjct: 794 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGN 831
Score = 41.9 bits (94), Expect = 0.003
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQI-ETLPDT 179
C GL EIP + + + N +K IP S KLR + L NNQI E PD
Sbjct: 290 CRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA 347
Query: 180 MDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQEHAL 222
+ +L L N++ + P S+ + L L LN+N+ + L
Sbjct: 348 FQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCL 391
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 45.2 bits (102), Expect = 4e-04
Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 6/155 (3%)
Query: 8 IRENHILALIEQAIAKKKS--RLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKISVFPVE 64
++ N + + +A+ +S L L+ I+ +P ++ L + HL+L N ++ PV+
Sbjct: 121 LQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQ 180
Query: 65 XXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFW 121
+ GNL +LV L+L N ++ L + D L LE
Sbjct: 181 AFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLD 240
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE 156
N L E P I L+ L G N +++IPE+
Sbjct: 241 LNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEK 275
Score = 37.9 bits (84), Expect = 0.057
Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 8/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE---IGDLEKLEA-FWCNRIGLKEIPKEIGKLTQL 140
PT I L NL L N + IPE +G+ + F+ N I L +L
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRS-IPEKAFVGNPSLITIHFYDNPIQFVG-RSAFQHLPEL 307
Query: 141 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQF 199
T G T ++T A L LTL QI +LP T+ +++ L +L N LE
Sbjct: 308 RTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 367
Query: 200 PSSILKCKELMFLQLNSNQ 218
PS + C++L + L N+
Sbjct: 368 PSFSV-CQKLQKIDLRHNE 385
Score = 35.1 bits (77), Expect = 0.40
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 130 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 187
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 188 HCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
L N + P S L L L+ N
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDN 172
Score = 30.7 bits (66), Expect = 8.6
Identities = 37/164 (22%), Positives = 71/164 (43%), Gaps = 7/164 (4%)
Query: 90 NLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGAR 146
+L L + L+ N ++ IP+ G+L L + + + K+ L L+T
Sbjct: 184 SLSALQAMTLALNKIHH-IPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSSILK 205
N L P + +L+ L+ L +N I ++P+ +L+ + +N ++ S +
Sbjct: 243 YNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQ 302
Query: 206 -CKELMFLQLN-SNQEHALIKYTDEATTQTSDSNGSLASAMPST 247
EL L LN ++Q T A ++ G+ S++P T
Sbjct: 303 HLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQT 346
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 45.2 bits (102), Expect = 4e-04
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 180
C+ GLK +PK I + + GN+ +P+E+++ L + L NN+I TL + +
Sbjct: 732 CSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSF 789
Query: 181 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
MT L+ L NRL P K L L L+ N
Sbjct: 790 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGN 827
Score = 41.9 bits (94), Expect = 0.003
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQI-ETLPDT 179
C GL EIP + + + N +K IP S KLR + L NNQI E PD
Sbjct: 286 CRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA 343
Query: 180 MDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQEHAL 222
+ +L L N++ + P S+ + L L LN+N+ + L
Sbjct: 344 FQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCL 387
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 45.2 bits (102), Expect = 4e-04
Identities = 53/212 (25%), Positives = 86/212 (40%), Gaps = 9/212 (4%)
Query: 14 LALIEQAIAKKKSRLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKIS-VFPVEXXXXXXX 71
L + + ++ L ++ IT++P + +E L L N +S + P
Sbjct: 129 LTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKEL 188
Query: 72 XXXXXXXXXXXXXPTE-IGNLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLK 128
P+E I L L +L L N + +PE L +L W + L
Sbjct: 189 KVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS-VPEDSFEGLVQLRHLWLDDNSLT 247
Query: 129 EIPKE-IGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPD-TMDRMTA 185
E+P + L L N++ +IP+ T+L+ L L L NN+I +L D +
Sbjct: 248 EVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDN 307
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 217
L +L N L +FP +I L L +SN
Sbjct: 308 LETLDLNYNNLGEFPQAIKALPSLKELGFHSN 339
Score = 39.9 bits (89), Expect = 0.014
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 4/132 (3%)
Query: 28 LSLNGFEITEIPGLLYTCL-EVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L L+ IT +P + L ++ HL+L N ++ PV
Sbjct: 215 LRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIP 274
Query: 87 EIG--NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
+ NL +LV L+L N + L D L+ LE N L E P+ I L L
Sbjct: 275 DFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKEL 334
Query: 144 GARGNELKTIPE 155
G N + IP+
Sbjct: 335 GFHSNSISVIPD 346
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 45.2 bits (102), Expect = 4e-04
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 180
C+ GLK +PK I + + GN+ +P+E+++ L + L NN+I TL + +
Sbjct: 740 CSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSF 797
Query: 181 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
MT L+ L NRL P K L L L+ N
Sbjct: 798 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGN 835
Score = 41.9 bits (94), Expect = 0.003
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQI-ETLPDT 179
C GL EIP + + + N +K IP S KLR + L NNQI E PD
Sbjct: 286 CRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA 343
Query: 180 MDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQEHAL 222
+ +L L N++ + P S+ + L L LN+N+ + L
Sbjct: 344 FQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCL 387
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 44.8 bits (101), Expect = 5e-04
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 5/99 (5%)
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTM 180
C+ GL +P+ + TQ GN+L I P+ ++ L +L+ LTL+NNQ++T+P
Sbjct: 43 CSGKGLTAVPEGLSAFTQ--ALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEA 100
Query: 181 DR-MTALVHCNLRNNRLEQFP-SSILKCKELMFLQLNSN 217
R ++AL L N + P S +L L L+ N
Sbjct: 101 IRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDN 139
Score = 44.4 bits (100), Expect = 7e-04
Identities = 42/139 (30%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 85 PTE-IGNLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIP-KEIGKLTQL 140
P+E I L L +L L N + +PE L +L W + L E+P + L L
Sbjct: 97 PSEAIRGLSALQSLRLDANHITS-VPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTL 155
Query: 141 DTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQ 198
N++ +IP+ T+L+ L L L NN+I +L D + L +L N L +
Sbjct: 156 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGE 215
Query: 199 FPSSILKCKELMFLQLNSN 217
FP +I L L +SN
Sbjct: 216 FPQAIKALPSLKELGFHSN 234
Score = 41.9 bits (94), Expect = 0.003
Identities = 38/138 (27%), Positives = 62/138 (44%), Gaps = 5/138 (3%)
Query: 85 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDT 142
P + LK L L L N L + E I L L++ + + +P++ + L QL
Sbjct: 74 PKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRH 133
Query: 143 FGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFP 200
N L +P +++L L+ LTL N+I ++PD +++LV +L NN++
Sbjct: 134 LWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLS 193
Query: 201 SSILK-CKELMFLQLNSN 217
L L LN N
Sbjct: 194 QHCFDGLDNLETLDLNYN 211
Score = 40.3 bits (90), Expect = 0.011
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 4/132 (3%)
Query: 28 LSLNGFEITEIPGLLYTCL-EVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L L+ IT +P + L ++ HL+L N ++ PV
Sbjct: 110 LRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIP 169
Query: 87 EIG--NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 143
+ NL +LV L+L N + L D L+ LE N L E P+ I L L
Sbjct: 170 DFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKEL 229
Query: 144 GARGNELKTIPE 155
G N + IP+
Sbjct: 230 GFHSNSISVIPD 241
>BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein.
Length = 384
Score = 44.4 bits (100), Expect = 7e-04
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L LN ++T+I P T ++ LYL N++S P+ T
Sbjct: 135 LILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDT 194
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFG 144
G + L L +S NPL+ E G E + F L +PK G L
Sbjct: 195 FKG-MNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPK--GLPPTLLELH 251
Query: 145 ARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
N++ T+ E+ +L+ L L NN+I + + ++ + + +L NN+L++ PS
Sbjct: 252 LDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSG 311
Query: 203 ILKCKELMFLQLNSN 217
+ + K L + L+SN
Sbjct: 312 LPELKYLQIIFLHSN 326
>AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein.
Length = 379
Score = 44.4 bits (100), Expect = 7e-04
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L LN ++T+I P T ++ LYL N++S P+ T
Sbjct: 130 LILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDT 189
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFG 144
G + L L +S NPL+ E G E + F L +PK G L
Sbjct: 190 FKG-MNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPK--GLPPTLLELH 246
Query: 145 ARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
N++ T+ E+ +L+ L L NN+I + + ++ + + +L NN+L++ PS
Sbjct: 247 LDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSG 306
Query: 203 ILKCKELMFLQLNSN 217
+ + K L + L+SN
Sbjct: 307 LPELKYLQIIFLHSN 321
>AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament
associated protein 1 protein.
Length = 381
Score = 44.4 bits (100), Expect = 7e-04
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L LN ++T+I P T ++ LYL N++S P+ T
Sbjct: 132 LILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDT 191
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFG 144
G + L L +S NPL+ E G E + F L +PK G L
Sbjct: 192 FKG-MNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPK--GLPPTLLELH 248
Query: 145 ARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
N++ T+ E+ +L+ L L NN+I + + ++ + + +L NN+L++ PS
Sbjct: 249 LDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSG 308
Query: 203 ILKCKELMFLQLNSN 217
+ + K L + L+SN
Sbjct: 309 LPELKYLQIIFLHSN 323
>AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1)
protein.
Length = 380
Score = 44.4 bits (100), Expect = 7e-04
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L LN ++T+I P T ++ LYL N++S P+ T
Sbjct: 131 LILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDT 190
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFG 144
G + L L +S NPL+ E G E + F L +PK G L
Sbjct: 191 FKG-MNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPK--GLPPTLLELH 247
Query: 145 ARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
N++ T+ E+ +L+ L L NN+I + + ++ + + +L NN+L++ PS
Sbjct: 248 LDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSG 307
Query: 203 ILKCKELMFLQLNSN 217
+ + K L + L+SN
Sbjct: 308 LPELKYLQIIFLHSN 322
>AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein.
Length = 379
Score = 44.4 bits (100), Expect = 7e-04
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 28 LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKISVFPVEXXXXXXXXXXXXXXXXXXXXPT 86
L LN ++T+I P T ++ LYL N++S P+ T
Sbjct: 130 LILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDT 189
Query: 87 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN--RIGLKEIPKEIGKLTQLDTFG 144
G + L L +S NPL+ E G E + F L +PK G L
Sbjct: 190 FKG-MNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPK--GLPPTLLELH 246
Query: 145 ARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 202
N++ T+ E+ +L+ L L NN+I + + ++ + + +L NN+L++ PS
Sbjct: 247 LDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSG 306
Query: 203 ILKCKELMFLQLNSN 217
+ + K L + L+SN
Sbjct: 307 LPELKYLQIIFLHSN 321
>Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein.
Length = 845
Score = 44.0 bits (99), Expect = 9e-04
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 201 -SSILK-CKELMFLQLNSN 217
+ +L+ +M +QL N
Sbjct: 198 FAGVLEHIGGIMEIQLEEN 216
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
NL +L L L+ N L VL P + D L+ L+ + +KEI P L L
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLP--DTMDRMTALVHCNLRNN 194
N L+++P+ + L L L NN LP +D++ A + +L+ N
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
Score = 39.1 bits (87), Expect = 0.025
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N +K I P +L L+ L L NN + +LPD + TAL NLRNN P
Sbjct: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLP 510
Score = 36.3 bits (80), Expect = 0.17
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 137 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 194
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ-EHALIK 224
L P +I L L L +N H +K
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVK 512
>BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 9e-04
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 201 -SSILK-CKELMFLQLNSN 217
+ +L+ +M +QL N
Sbjct: 198 FAGVLEHIGGIMEIQLEEN 216
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
NL +L L L+ N L VL P + D L+ L+ + +KEI P L L
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLP--DTMDRMTALVHCNLRNN 194
N L+++P+ + L L L NN LP +D++ A + +L+ N
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
Score = 39.1 bits (87), Expect = 0.025
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N +K I P +L L+ L L NN + +LPD + TAL NLRNN P
Sbjct: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLP 510
Score = 36.3 bits (80), Expect = 0.17
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 137 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 194
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ-EHALIK 224
L P +I L L L +N H +K
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVK 512
>BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 9e-04
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 201 -SSILK-CKELMFLQLNSN 217
+ +L+ +M +QL N
Sbjct: 198 FAGVLEHIGGIMEIQLEEN 216
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
NL +L L L+ N L VL P + D L+ L+ + +KEI P L L
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLP--DTMDRMTALVHCNLRNN 194
N L+++P+ + L L L NN LP +D++ A + +L+ N
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
Score = 39.1 bits (87), Expect = 0.025
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N +K I P +L L+ L L NN + +LPD + TAL NLRNN P
Sbjct: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLP 510
Score = 36.3 bits (80), Expect = 0.17
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 137 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 194
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ-EHALIK 224
L P +I L L L +N H +K
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVK 512
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 44.0 bits (99), Expect = 9e-04
Identities = 48/183 (26%), Positives = 76/183 (41%), Gaps = 7/183 (3%)
Query: 26 SRLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKIS-VFPVEXXXXXXXXXXXXXXXXXXX 83
S L L + EI + L +E LYL KN+I + P
Sbjct: 103 SNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRA 162
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDT 142
P L L+ L+LS+N L L P I D +EA +GL+++ + + +L L
Sbjct: 163 LPPL--RLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHD 220
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLE-NNQIETL-PDTMDRMTALVHCNLRNNRLEQFP 200
N+L+ +P + L L L L N +I L P+ + + AL ++ N L+ P
Sbjct: 221 LDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALP 280
Query: 201 SSI 203
+
Sbjct: 281 GDL 283
>BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like family,
member 4 protein.
Length = 837
Score = 44.0 bits (99), Expect = 9e-04
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%)
Query: 44 TCLEVEH-LYLHKNKISVF---PVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNL 99
+C+ VE+ LY++ K+SV+ ++ P N + V+L+L
Sbjct: 31 SCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHL 90
Query: 100 SYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTFGARGNELKTIPE- 155
N L N+ L L+ N LK + + +G + L+ A N +K I
Sbjct: 91 GNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLG-IENLEYLQADYNLIKYIERG 149
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
L KL+ L L +N I LPD + R +L H ++R NR+++ P
Sbjct: 150 AFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLP 194
Score = 38.7 bits (86), Expect = 0.032
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 4/130 (3%)
Query: 93 NLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNEL 150
N L+++ N + +V + + D E L+ + I ++ LT L GN++
Sbjct: 378 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 437
Query: 151 KTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKE 208
+ + PE + L L++L LE N I+ + T D M L L NN L+ P I
Sbjct: 438 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 497
Query: 209 LMFLQLNSNQ 218
L L L +N+
Sbjct: 498 LARLNLRNNK 507
Score = 33.1 bits (72), Expect = 1.6
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTF 143
++ + + L L+L N + V+ ++ +L L + N ++ + EI L L
Sbjct: 395 SDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYL 454
Query: 144 GARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
N +K I S+ L+ L L NN +++LP + L NLRNN+ P S
Sbjct: 455 YLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVS 514
>BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein.
Length = 352
Score = 44.0 bits (99), Expect = 9e-04
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 7/101 (6%)
Query: 119 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETL- 176
A +C GLKEIP ++ L + N ++TIPE+ + +LRW+ L N+I
Sbjct: 55 ALYCENRGLKEIPAIPSRIWYL---YLQNNLIETIPEKPFENATQLRWINLNKNKITNYG 111
Query: 177 --PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ ++ L+ L +N LE+ PS + + E + L N
Sbjct: 112 IEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARN 152
Score = 34.7 bits (76), Expect = 0.53
Identities = 19/62 (30%), Positives = 36/62 (58%), Gaps = 4/62 (6%)
Query: 161 AKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQF---PSSILKCKELMFLQLNS 216
+++ +L L+NN IET+P+ + T L NL N++ + ++ + K+L+FL L
Sbjct: 71 SRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLED 130
Query: 217 NQ 218
N+
Sbjct: 131 NE 132
Score = 31.5 bits (68), Expect = 4.9
Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 6/110 (5%)
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLE 169
+ L+KL + L+E+P + + L+ N++ IP+ ++L L L L+
Sbjct: 117 LSQLKKLLFLFLEDNELEEVPSPLPR--SLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
Query: 170 NNQIETLP---DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
NN++ DT + L+ N+ N L P + +FL NS
Sbjct: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNS 224
>BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein.
Length = 601
Score = 44.0 bits (99), Expect = 9e-04
Identities = 48/183 (26%), Positives = 76/183 (41%), Gaps = 7/183 (3%)
Query: 26 SRLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKIS-VFPVEXXXXXXXXXXXXXXXXXXX 83
S L L + EI + L +E LYL KN+I + P
Sbjct: 31 SNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRA 90
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDT 142
P L L+ L+LS+N L L P I D +EA +GL+++ + + +L L
Sbjct: 91 LPPL--RLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHD 148
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLE-NNQIETL-PDTMDRMTALVHCNLRNNRLEQFP 200
N+L+ +P + L L L L N +I L P+ + + AL ++ N L+ P
Sbjct: 149 LDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALP 208
Query: 201 SSI 203
+
Sbjct: 209 GDL 211
>AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein.
Length = 733
Score = 44.0 bits (99), Expect = 9e-04
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 201 -SSILK-CKELMFLQLNSN 217
+ +L+ +M +QL N
Sbjct: 198 FAGVLEHIGGIMEIQLEEN 216
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
NL +L L L+ N L VL P + D L+ L+ + +KEI P L L
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLP--DTMDRMTALVHCNLRNN 194
N L+++P+ + L L L NN LP +D++ A + +L+ N
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
Score = 39.1 bits (87), Expect = 0.025
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N +K I P +L L+ L L NN + +LPD + TAL NLRNN P
Sbjct: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLP 510
Score = 36.3 bits (80), Expect = 0.17
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 137 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 194
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ-EHALIK 224
L P +I L L L +N H +K
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVK 512
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 44.0 bits (99), Expect = 9e-04
Identities = 48/183 (26%), Positives = 76/183 (41%), Gaps = 7/183 (3%)
Query: 26 SRLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKIS-VFPVEXXXXXXXXXXXXXXXXXXX 83
S L L + EI + L +E LYL KN+I + P
Sbjct: 103 SNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRA 162
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDT 142
P L L+ L+LS+N L L P I D +EA +GL+++ + + +L L
Sbjct: 163 LPPL--RLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHD 220
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLE-NNQIETL-PDTMDRMTALVHCNLRNNRLEQFP 200
N+L+ +P + L L L L N +I L P+ + + AL ++ N L+ P
Sbjct: 221 LDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALP 280
Query: 201 SSI 203
+
Sbjct: 281 GDL 283
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 44.0 bits (99), Expect = 9e-04
Identities = 48/183 (26%), Positives = 76/183 (41%), Gaps = 7/183 (3%)
Query: 26 SRLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKIS-VFPVEXXXXXXXXXXXXXXXXXXX 83
S L L + EI + L +E LYL KN+I + P
Sbjct: 103 SNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRA 162
Query: 84 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDT 142
P L L+ L+LS+N L L P I D +EA +GL+++ + + +L L
Sbjct: 163 LPPL--RLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHD 220
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLE-NNQIETL-PDTMDRMTALVHCNLRNNRLEQFP 200
N+L+ +P + L L L L N +I L P+ + + AL ++ N L+ P
Sbjct: 221 LDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALP 280
Query: 201 SSI 203
+
Sbjct: 281 GDL 283
>AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 9e-04
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 201 -SSILK-CKELMFLQLNSN 217
+ +L+ +M +QL N
Sbjct: 198 FAGVLEHIGGIMEIQLEEN 216
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
NL +L L L+ N L VL P + D L+ L+ + +KEI P L L
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLP--DTMDRMTALVHCNLRNN 194
N L+++P+ + L L L NN LP +D++ A + +L+ N
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
Score = 39.1 bits (87), Expect = 0.025
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N +K I P +L L+ L L NN + +LPD + TAL NLRNN P
Sbjct: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLP 510
Score = 36.3 bits (80), Expect = 0.17
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 137 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 194
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ-EHALIK 224
L P +I L L L +N H +K
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVK 512
>AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 724
Score = 44.0 bits (99), Expect = 9e-04
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 201 -SSILK-CKELMFLQLNSN 217
+ +L+ +M +QL N
Sbjct: 198 FAGVLEHIGGIMEIQLEEN 216
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
NL +L L L+ N L VL P + D L+ L+ + +KEI P L L
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLP--DTMDRMTALVHCNLRNN 194
N L+++P+ + L L L NN LP +D++ A + +L+ N
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
Score = 39.1 bits (87), Expect = 0.025
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N +K I P +L L+ L L NN + +LPD + TAL NLRNN P
Sbjct: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLP 510
Score = 36.3 bits (80), Expect = 0.17
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 137 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 194
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ-EHALIK 224
L P +I L L L +N H +K
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVK 512
>AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein.
Length = 837
Score = 44.0 bits (99), Expect = 9e-04
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%)
Query: 44 TCLEVEH-LYLHKNKISVF---PVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNL 99
+C+ VE+ LY++ K+SV+ ++ P N + V+L+L
Sbjct: 31 SCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHL 90
Query: 100 SYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTFGARGNELKTIPE- 155
N L N+ L L+ N LK + + +G + L+ A N +K I
Sbjct: 91 GNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLG-IENLEYLQADYNLIKYIERG 149
Query: 156 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
L KL+ L L +N I LPD + R +L H ++R NR+++ P
Sbjct: 150 AFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLP 194
Score = 38.7 bits (86), Expect = 0.032
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 4/130 (3%)
Query: 93 NLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNEL 150
N L+++ N + +V + + D E L+ + I ++ LT L GN++
Sbjct: 378 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 437
Query: 151 KTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKE 208
+ + PE + L L++L LE N I+ + T D M L L NN L+ P I
Sbjct: 438 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 497
Query: 209 LMFLQLNSNQ 218
L L L +N+
Sbjct: 498 LARLNLRNNK 507
Score = 33.1 bits (72), Expect = 1.6
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 86 TEIGNLKNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTF 143
++ + + L L+L N + V+ ++ +L L + N ++ + EI L L
Sbjct: 395 SDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYL 454
Query: 144 GARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 202
N +K I S+ L+ L L NN +++LP + L NLRNN+ P S
Sbjct: 455 YLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVS 514
>AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens
cDNA FLJ33696 fis, clone BRAWH2003964, weakly similar to
SLIT PROTEIN PRECURSOR. ).
Length = 724
Score = 44.0 bits (99), Expect = 9e-04
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 201 -SSILK-CKELMFLQLNSN 217
+ +L+ +M +QL N
Sbjct: 198 FAGVLEHIGGIMEIQLEEN 216
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
NL +L L L+ N L VL P + D L+ L+ + +KEI P L L
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLP--DTMDRMTALVHCNLRNN 194
N L+++P+ + L L L NN LP +D++ A + +L+ N
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
Score = 39.1 bits (87), Expect = 0.025
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N +K I P +L L+ L L NN + +LPD + TAL NLRNN P
Sbjct: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLP 510
Score = 36.3 bits (80), Expect = 0.17
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 137 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 194
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ-EHALIK 224
L P +I L L L +N H +K
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVK 512
>AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein.
Length = 352
Score = 44.0 bits (99), Expect = 9e-04
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 7/101 (6%)
Query: 119 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETL- 176
A +C GLKEIP ++ L + N ++TIPE+ + +LRW+ L N+I
Sbjct: 55 ALYCENRGLKEIPAIPSRIWYL---YLQNNLIETIPEKPFENATQLRWINLNKNKITNYG 111
Query: 177 --PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ ++ L+ L +N LE+ PS + + E + L N
Sbjct: 112 IEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARN 152
Score = 34.7 bits (76), Expect = 0.53
Identities = 19/62 (30%), Positives = 36/62 (58%), Gaps = 4/62 (6%)
Query: 161 AKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQF---PSSILKCKELMFLQLNS 216
+++ +L L+NN IET+P+ + T L NL N++ + ++ + K+L+FL L
Sbjct: 71 SRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLED 130
Query: 217 NQ 218
N+
Sbjct: 131 NE 132
Score = 31.5 bits (68), Expect = 4.9
Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 6/110 (5%)
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLE 169
+ L+KL + L+E+P + + L+ N++ IP+ ++L L L L+
Sbjct: 117 LSQLKKLLFLFLEDNELEEVPSPLPR--SLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
Query: 170 NNQIETLP---DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
NN++ DT + L+ N+ N L P + +FL NS
Sbjct: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNS 224
>AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein.
Length = 352
Score = 44.0 bits (99), Expect = 9e-04
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 7/101 (6%)
Query: 119 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETL- 176
A +C GLKEIP ++ L + N ++TIPE+ + +LRW+ L N+I
Sbjct: 55 ALYCENRGLKEIPAIPSRIWYL---YLQNNLIETIPEKPFENATQLRWINLNKNKITNYG 111
Query: 177 --PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ ++ L+ L +N LE+ PS + + E + L N
Sbjct: 112 IEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARN 152
Score = 34.7 bits (76), Expect = 0.53
Identities = 19/62 (30%), Positives = 36/62 (58%), Gaps = 4/62 (6%)
Query: 161 AKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQF---PSSILKCKELMFLQLNS 216
+++ +L L+NN IET+P+ + T L NL N++ + ++ + K+L+FL L
Sbjct: 71 SRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLED 130
Query: 217 NQ 218
N+
Sbjct: 131 NE 132
Score = 31.5 bits (68), Expect = 4.9
Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 6/110 (5%)
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLE 169
+ L+KL + L+E+P + + L+ N++ IP+ ++L L L L+
Sbjct: 117 LSQLKKLLFLFLEDNELEEVPSPLPR--SLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
Query: 170 NNQIETLP---DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
NN++ DT + L+ N+ N L P + +FL NS
Sbjct: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNS 224
>AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate
proteoglycan protein.
Length = 352
Score = 44.0 bits (99), Expect = 9e-04
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 7/101 (6%)
Query: 119 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETL- 176
A +C GLKEIP ++ L + N ++TIPE+ + +LRW+ L N+I
Sbjct: 55 ALYCENRGLKEIPAIPSRIWYL---YLQNNLIETIPEKPFENATQLRWINLNKNKITNYG 111
Query: 177 --PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 215
+ ++ L+ L +N LE+ PS + + E + L N
Sbjct: 112 IEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARN 152
Score = 34.7 bits (76), Expect = 0.53
Identities = 19/62 (30%), Positives = 36/62 (58%), Gaps = 4/62 (6%)
Query: 161 AKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQF---PSSILKCKELMFLQLNS 216
+++ +L L+NN IET+P+ + T L NL N++ + ++ + K+L+FL L
Sbjct: 71 SRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLED 130
Query: 217 NQ 218
N+
Sbjct: 131 NE 132
Score = 31.5 bits (68), Expect = 4.9
Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 6/110 (5%)
Query: 111 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLE 169
+ L+KL + L+E+P + + L+ N++ IP+ ++L L L L+
Sbjct: 117 LSQLKKLLFLFLEDNELEEVPSPLPR--SLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
Query: 170 NNQIETLP---DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
NN++ DT + L+ N+ N L P + +FL NS
Sbjct: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNS 224
>AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein.
Length = 572
Score = 44.0 bits (99), Expect = 9e-04
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 85 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 141
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 85 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 143
Query: 142 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 144 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 203
Query: 201 -SSILK-CKELMFLQLNSN 217
+ +L+ +M +QL N
Sbjct: 204 FAGVLEHIGGIMEIQLEEN 222
Score = 44.0 bits (99), Expect = 9e-04
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
NL +L L L+ N L VL P + D L+ L+ + +KEI P L L
Sbjct: 427 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 486
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLP--DTMDRMTALVHCNLRNN 194
N L+++P+ + L L L NN LP +D++ A + +L+ N
Sbjct: 487 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 535
Score = 39.1 bits (87), Expect = 0.025
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N +K I P +L L+ L L NN + +LPD + TAL NLRNN P
Sbjct: 463 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLP 516
Score = 36.3 bits (80), Expect = 0.17
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 137 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 194
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 428 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 487
Query: 195 RLEQFPSSILKCKELMFLQLNSNQ-EHALIK 224
L P +I L L L +N H +K
Sbjct: 488 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVK 518
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 6/122 (4%)
Query: 140 LDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA-LVHCNLRNNRLE 197
L++ N + I +L++L L NN+I TL D +++ L+ L NR+
Sbjct: 146 LESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMS 205
Query: 198 QFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALA 257
P I K L FL+L N+ IK + T Q DS SL S++
Sbjct: 206 MIPPKIFKLPHLQFLELKRNR----IKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFG 261
Query: 258 LN 259
LN
Sbjct: 262 LN 263
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 6/122 (4%)
Query: 140 LDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA-LVHCNLRNNRLE 197
L++ N + I +L++L L NN+I TL D +++ L+ L NR+
Sbjct: 146 LESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMS 205
Query: 198 QFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALA 257
P I K L FL+L N+ IK + T Q DS SL S++
Sbjct: 206 MIPPKIFKLPHLQFLELKRNR----IKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFG 261
Query: 258 LN 259
LN
Sbjct: 262 LN 263
>BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein.
Length = 512
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/130 (28%), Positives = 64/130 (49%), Gaps = 9/130 (6%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGARGNELKT 152
+ L+LS N L+ L P + LE + ++P+ + + TQL + N+L
Sbjct: 197 IATLSLSNNQLSYLPPSLPP--SLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTD 254
Query: 153 IPEEMTSLAKLR---WLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK-CKE 208
+ T+ +KL +L L +NQ+ T+P + R A++H L NR+ Q ++ L +
Sbjct: 255 SGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILH--LGRNRIRQVEAARLHGARG 312
Query: 209 LMFLQLNSNQ 218
L +L L NQ
Sbjct: 313 LRYLLLQHNQ 322
Score = 37.9 bits (84), Expect = 0.057
Identities = 20/57 (35%), Positives = 35/57 (61%), Gaps = 3/57 (5%)
Query: 139 QLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNN 194
++DT G +L+ P+ +T A+ L+L+NNQ++ LP + + R++ L NL NN
Sbjct: 54 RVDTVDCDGLDLRVFPDNITRAAQ--HLSLQNNQLQELPYNELSRLSGLRTLNLHNN 108
>BC024001-1|AAH24001.1| 184|Homo sapiens leucine rich repeat
containing 20 protein.
Length = 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA 185
L +P E+ L L N+ + PE++T+L L + LE N+I +P + + M A
Sbjct: 86 LHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPA 145
Query: 186 LVHCNLRNNRL 196
L NLR N L
Sbjct: 146 LRSINLRFNPL 156
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 125 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 183
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 184 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L +L N+ + FP + L + L N+
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENE 131
Score = 39.5 bits (88), Expect = 0.019
Identities = 19/63 (30%), Positives = 31/63 (49%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
+QL GN L +P E+++L L+ + L NQ + P+ + + AL NL N +
Sbjct: 74 SQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIV 133
Query: 198 QFP 200
P
Sbjct: 134 DVP 136
Score = 37.5 bits (83), Expect = 0.075
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L+L N L+ L E+ L+ L+A +R ++ P+++ L L+T NE+ +
Sbjct: 76 LRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDV 135
Query: 154 P-EEMTSLAKLRWLTLENNQI 173
P E++ ++ LR + L N +
Sbjct: 136 PVEKLAAMPALRSINLRFNPL 156
>AY358318-1|AAQ88684.1| 184|Homo sapiens LKKM2429 protein.
Length = 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA 185
L +P E+ L L N+ + PE++T+L L + LE N+I +P + + M A
Sbjct: 86 LHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPA 145
Query: 186 LVHCNLRNNRL 196
L NLR N L
Sbjct: 146 LRSINLRFNPL 156
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 125 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 183
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 184 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L +L N+ + FP + L + L N+
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENE 131
Score = 39.5 bits (88), Expect = 0.019
Identities = 19/63 (30%), Positives = 31/63 (49%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
+QL GN L +P E+++L L+ + L NQ + P+ + + AL NL N +
Sbjct: 74 SQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIV 133
Query: 198 QFP 200
P
Sbjct: 134 DVP 136
Score = 37.5 bits (83), Expect = 0.075
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L+L N L+ L E+ L+ L+A +R ++ P+++ L L+T NE+ +
Sbjct: 76 LRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDV 135
Query: 154 P-EEMTSLAKLRWLTLENNQI 173
P E++ ++ LR + L N +
Sbjct: 136 PVEKLAAMPALRSINLRFNPL 156
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 6/122 (4%)
Query: 140 LDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA-LVHCNLRNNRLE 197
L++ N + I +L++L L NN+I TL D +++ L+ L NR+
Sbjct: 146 LESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMS 205
Query: 198 QFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALA 257
P I K L FL+L N+ IK + T Q DS SL S++
Sbjct: 206 MIPPKIFKLPHLQFLELKRNR----IKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFG 261
Query: 258 LN 259
LN
Sbjct: 262 LN 263
>AL355138-5|CAI12601.1| 134|Homo sapiens leucine rich repeat
containing 20 protein.
Length = 134
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA 185
L +P E+ L L N+ + PE++T+L L + LE N+I +P + + M A
Sbjct: 36 LHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPA 95
Query: 186 LVHCNLRNNRL 196
L NLR N L
Sbjct: 96 LRSINLRFNPL 106
Score = 37.9 bits (84), Expect = 0.057
Identities = 17/54 (31%), Positives = 28/54 (51%)
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
GN L +P E+++L L+ + L NQ + P+ + + AL NL N + P
Sbjct: 33 GNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
Score = 37.5 bits (83), Expect = 0.075
Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ L+L N L+ L E+ L+ L+A +R ++ P+++ L L+T NE+ +P
Sbjct: 27 LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
Query: 155 -EEMTSLAKLRWLTLENNQI 173
E++ ++ LR + L N +
Sbjct: 87 VEKLAAMPALRSINLRFNPL 106
>AL355138-4|CAI12602.1| 175|Homo sapiens leucine rich repeat
containing 20 protein.
Length = 175
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA 185
L +P E+ L L N+ + PE++T+L L + LE N+I +P + + M A
Sbjct: 86 LHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPA 145
Query: 186 LVHCNLRNNRL 196
L NLR N L
Sbjct: 146 LRSINLRFNPL 156
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 125 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 183
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 184 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L +L N+ + FP + L + L N+
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENE 131
Score = 39.5 bits (88), Expect = 0.019
Identities = 19/63 (30%), Positives = 31/63 (49%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
+QL GN L +P E+++L L+ + L NQ + P+ + + AL NL N +
Sbjct: 74 SQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIV 133
Query: 198 QFP 200
P
Sbjct: 134 DVP 136
Score = 37.5 bits (83), Expect = 0.075
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L+L N L+ L E+ L+ L+A +R ++ P+++ L L+T NE+ +
Sbjct: 76 LRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDV 135
Query: 154 P-EEMTSLAKLRWLTLENNQI 173
P E++ ++ LR + L N +
Sbjct: 136 PVEKLAAMPALRSINLRFNPL 156
>AL355138-2|CAI12600.1| 184|Homo sapiens leucine rich repeat
containing 20 protein.
Length = 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA 185
L +P E+ L L N+ + PE++T+L L + LE N+I +P + + M A
Sbjct: 86 LHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPA 145
Query: 186 LVHCNLRNNRL 196
L NLR N L
Sbjct: 146 LRSINLRFNPL 156
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 125 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 183
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 184 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L +L N+ + FP + L + L N+
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENE 131
Score = 39.5 bits (88), Expect = 0.019
Identities = 19/63 (30%), Positives = 31/63 (49%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
+QL GN L +P E+++L L+ + L NQ + P+ + + AL NL N +
Sbjct: 74 SQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIV 133
Query: 198 QFP 200
P
Sbjct: 134 DVP 136
Score = 37.5 bits (83), Expect = 0.075
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L+L N L+ L E+ L+ L+A +R ++ P+++ L L+T NE+ +
Sbjct: 76 LRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDV 135
Query: 154 P-EEMTSLAKLRWLTLENNQI 173
P E++ ++ LR + L N +
Sbjct: 136 PVEKLAAMPALRSINLRFNPL 156
>AK094734-1|BAC04409.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ37415 fis, clone BRAWH2000232. ).
Length = 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA 185
L +P E+ L L N+ + PE++T+L L + LE N+I +P + + M A
Sbjct: 86 LHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPA 145
Query: 186 LVHCNLRNNRL 196
L NLR N L
Sbjct: 146 LRSINLRFNPL 156
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 125 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 183
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 184 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L +L N+ + FP + L + L N+
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENE 131
Score = 39.5 bits (88), Expect = 0.019
Identities = 19/63 (30%), Positives = 31/63 (49%)
Query: 138 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 197
+QL GN L +P E+++L L+ + L NQ + P+ + + AL NL N +
Sbjct: 74 SQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIV 133
Query: 198 QFP 200
P
Sbjct: 134 DVP 136
Score = 37.5 bits (83), Expect = 0.075
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Query: 94 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 153
L L+L N L+ L E+ L+ L+A +R ++ P+++ L L+T NE+ +
Sbjct: 76 LRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDV 135
Query: 154 P-EEMTSLAKLRWLTLENNQI 173
P E++ ++ LR + L N +
Sbjct: 136 PVEKLAAMPALRSINLRFNPL 156
>AK001706-1|BAA91849.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ10844 fis, clone NT2RP4001353. ).
Length = 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA 185
L +P E+ L L N+ + PE++T+L L + LE N+I +P + + M A
Sbjct: 36 LHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPA 95
Query: 186 LVHCNLRNNRL 196
L NLR N L
Sbjct: 96 LRSINLRFNPL 106
Score = 37.9 bits (84), Expect = 0.057
Identities = 17/54 (31%), Positives = 28/54 (51%)
Query: 147 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
GN L +P E+++L L+ + L NQ + P+ + + AL NL N + P
Sbjct: 33 GNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
Score = 37.5 bits (83), Expect = 0.075
Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 95 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 154
+ L+L N L+ L E+ L+ L+A +R ++ P+++ L L+T NE+ +P
Sbjct: 27 LELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVP 86
Query: 155 -EEMTSLAKLRWLTLENNQI 173
E++ ++ LR + L N +
Sbjct: 87 VEKLAAMPALRSINLRFNPL 106
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 6/122 (4%)
Query: 140 LDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTA-LVHCNLRNNRLE 197
L++ N + I +L++L L NN+I TL D +++ L+ L NR+
Sbjct: 154 LESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMS 213
Query: 198 QFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMPSTSRVYGAQALA 257
P I K L FL+L N+ IK + T Q DS SL S++
Sbjct: 214 MIPPKIFKLPHLQFLELKRNR----IKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFG 269
Query: 258 LN 259
LN
Sbjct: 270 LN 271
>BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like family,
member 3 protein.
Length = 977
Score = 43.2 bits (97), Expect = 0.002
Identities = 42/135 (31%), Positives = 66/135 (48%), Gaps = 8/135 (5%)
Query: 90 NLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWC--NRIGLKEIPKEIGKLTQLDTFGAR 146
+L N V++NL N L ++ L+ L+ + N++ + +G L L+ A
Sbjct: 99 HLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFLG-LESLEYLQAD 157
Query: 147 GNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE-QFPSSIL 204
N +K I +L+KLR L L +N I LP + + +L H +LR NRL+ F +L
Sbjct: 158 YNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVSLTHLDLRGNRLKVLFYRGML 217
Query: 205 K--CKELMFLQLNSN 217
+ LM LQL N
Sbjct: 218 DHIGRSLMELQLEEN 232
Score = 31.5 bits (68), Expect = 4.9
Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 5/137 (3%)
Query: 86 TEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTF 143
++ N +L L+L N ++ V +L L++ + N ++++ P L L
Sbjct: 426 SDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYL 485
Query: 144 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-S 201
N ++ I P + + L+ L L NN + TLP T+L NLR N P +
Sbjct: 486 YFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARLNLRKNYFLYLPVA 545
Query: 202 SILK-CKELMFLQLNSN 217
+L+ ++ + LN N
Sbjct: 546 GVLEHLNAIVQIDLNEN 562
>BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein.
Length = 465
Score = 43.2 bits (97), Expect = 0.002
Identities = 25/100 (25%), Positives = 51/100 (51%)
Query: 123 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 182
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 126 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 185
Query: 183 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHAL 222
+ V N LE P+ ++K L FL ++N+ +L
Sbjct: 186 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESL 225
Score = 35.9 bits (79), Expect = 0.23
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 6/131 (4%)
Query: 127 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 185
L+ P ++ KL +L+ GN+LK IP + + ++ + +N IE P+ M ++
Sbjct: 272 LQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVM-QLPE 330
Query: 186 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQEHALIKYTDEATTQTSDSNGSLASAMP 245
+ +L N L + +L L L N L D T + ++ P
Sbjct: 331 IKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL----DHKTLELLNNIRCFKIDQP 386
Query: 246 STSRVYGAQAL 256
ST GA A+
Sbjct: 387 STGDASGAPAV 397
>BC050097-1|AAH50097.1| 383|Homo sapiens LRRC27 protein protein.
Length = 383
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT-QLDTFGARGNELKTIPEEMTSLAKLRWL 166
+ E+ + L+ R L IP++ +L L R N +K +P + + L+ L
Sbjct: 60 LEEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTL 119
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
LE N I+ LP + +T L NLR+ LE FP ++ K L+ +Q
Sbjct: 120 LLERNPIKMLPVELGSVTTLKALNLRHCPLE-FPPQLVVQKGLVAIQ 165
Score = 34.7 bits (76), Expect = 0.53
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L NL L+L YN + L IG + L+ R +K +P E+G +T L R L
Sbjct: 90 LPNLTWLDLRYNRIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPL 149
Query: 151 KTIPE 155
+ P+
Sbjct: 150 EFPPQ 154
Score = 31.9 bits (69), Expect = 3.7
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLA-KLRWLTLENNQIETLPDTMDRMTALVHCN 190
+E+ ++ L + N L IP++ L L WL L N+I+ LP + L
Sbjct: 61 EEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTLL 120
Query: 191 LRNNRLEQFPSSILKCKELMFLQL 214
L N ++ P + L L L
Sbjct: 121 LERNPIKMLPVELGSVTTLKALNL 144
>BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 43.2 bits (97), Expect = 0.002
Identities = 38/136 (27%), Positives = 69/136 (50%), Gaps = 10/136 (7%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD--LEKLEAFWCNRIGLKEIP-KEIGKLTQLDTFGAR 146
NL L L++S N L+ L + D L+ + GLK K++ L L+T
Sbjct: 648 NLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLS 707
Query: 147 GNELKTIPEEMTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLE-----QF 199
N+L T+PE +++ ++ L+ L L+NNQI +L + L + +L +N+++ F
Sbjct: 708 HNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSF 767
Query: 200 PSSILKCKELMFLQLN 215
P ++L +++ L N
Sbjct: 768 PENVLNNLKMLLLHHN 783
>AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein.
Length = 1049
Score = 43.2 bits (97), Expect = 0.002
Identities = 38/136 (27%), Positives = 69/136 (50%), Gaps = 10/136 (7%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD--LEKLEAFWCNRIGLKEIP-KEIGKLTQLDTFGAR 146
NL L L++S N L+ L + D L+ + GLK K++ L L+T
Sbjct: 648 NLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLS 707
Query: 147 GNELKTIPEEMTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLE-----QF 199
N+L T+PE +++ ++ L+ L L+NNQI +L + L + +L +N+++ F
Sbjct: 708 HNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSF 767
Query: 200 PSSILKCKELMFLQLN 215
P ++L +++ L N
Sbjct: 768 PENVLNNLKMLLLHHN 783
>AL590105-6|CAI13017.1| 530|Homo sapiens novel protein protein.
Length = 530
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT-QLDTFGARGNELKTIPEEMTSLAKLRWL 166
+ E+ + L+ R L IP++ +L L R N +K +P + + L+ L
Sbjct: 60 LEEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTL 119
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
LE N I+ LP + +T L NLR+ LE FP ++ K L+ +Q
Sbjct: 120 LLERNPIKMLPVELGSVTTLKALNLRHCPLE-FPPQLVVQKGLVAIQ 165
Score = 34.7 bits (76), Expect = 0.53
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L NL L+L YN + L IG + L+ R +K +P E+G +T L R L
Sbjct: 90 LPNLTWLDLRYNRIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPL 149
Query: 151 KTIPE 155
+ P+
Sbjct: 150 EFPPQ 154
Score = 31.9 bits (69), Expect = 3.7
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLA-KLRWLTLENNQIETLPDTMDRMTALVHCN 190
+E+ ++ L + N L IP++ L L WL L N+I+ LP + L
Sbjct: 61 EEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTLL 120
Query: 191 LRNNRLEQFPSSILKCKELMFLQL 214
L N ++ P + L L L
Sbjct: 121 LERNPIKMLPVELGSVTTLKALNL 144
>AL590105-5|CAI13016.1| 383|Homo sapiens novel protein protein.
Length = 383
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT-QLDTFGARGNELKTIPEEMTSLAKLRWL 166
+ E+ + L+ R L IP++ +L L R N +K +P + + L+ L
Sbjct: 60 LEEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTL 119
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
LE N I+ LP + +T L NLR+ LE FP ++ K L+ +Q
Sbjct: 120 LLERNPIKMLPVELGSVTTLKALNLRHCPLE-FPPQLVVQKGLVAIQ 165
Score = 34.7 bits (76), Expect = 0.53
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L NL L+L YN + L IG + L+ R +K +P E+G +T L R L
Sbjct: 90 LPNLTWLDLRYNRIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPL 149
Query: 151 KTIPE 155
+ P+
Sbjct: 150 EFPPQ 154
Score = 31.9 bits (69), Expect = 3.7
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLA-KLRWLTLENNQIETLPDTMDRMTALVHCN 190
+E+ ++ L + N L IP++ L L WL L N+I+ LP + L
Sbjct: 61 EEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTLL 120
Query: 191 LRNNRLEQFPSSILKCKELMFLQL 214
L N ++ P + L L L
Sbjct: 121 LERNPIKMLPVELGSVTTLKALNL 144
>AK098652-1|BAC05366.1| 383|Homo sapiens protein ( Homo sapiens
cDNA FLJ25786 fis, clone TST06852. ).
Length = 383
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT-QLDTFGARGNELKTIPEEMTSLAKLRWL 166
+ E+ + L+ R L IP++ +L L R N +K +P + + L+ L
Sbjct: 60 LEEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTL 119
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
LE N I+ LP + +T L NLR+ LE FP ++ K L+ +Q
Sbjct: 120 LLERNPIKMLPVELGSVTTLKALNLRHCPLE-FPPQLVVQKGLVAIQ 165
Score = 34.7 bits (76), Expect = 0.53
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L NL L+L YN + L IG + L+ R +K +P E+G +T L R L
Sbjct: 90 LPNLTWLDLRYNRIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPL 149
Query: 151 KTIPE 155
+ P+
Sbjct: 150 EFPPQ 154
Score = 31.9 bits (69), Expect = 3.7
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLA-KLRWLTLENNQIETLPDTMDRMTALVHCN 190
+E+ ++ L + N L IP++ L L WL L N+I+ LP + L
Sbjct: 61 EEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTLL 120
Query: 191 LRNNRLEQFPSSILKCKELMFLQL 214
L N ++ P + L L L
Sbjct: 121 LERNPIKMLPVELGSVTTLKALNL 144
>AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 43.2 bits (97), Expect = 0.002
Identities = 38/136 (27%), Positives = 69/136 (50%), Gaps = 10/136 (7%)
Query: 90 NLKNLVNLNLSYNPLNVLIPEIGD--LEKLEAFWCNRIGLKEIP-KEIGKLTQLDTFGAR 146
NL L L++S N L+ L + D L+ + GLK K++ L L+T
Sbjct: 648 NLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLS 707
Query: 147 GNELKTIPEEMTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLE-----QF 199
N+L T+PE +++ ++ L+ L L+NNQI +L + L + +L +N+++ F
Sbjct: 708 HNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSF 767
Query: 200 PSSILKCKELMFLQLN 215
P ++L +++ L N
Sbjct: 768 PENVLNNLKMLLLHHN 783
>AB051461-1|BAB21765.1| 538|Homo sapiens KIAA1674 protein protein.
Length = 538
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 108 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT-QLDTFGARGNELKTIPEEMTSLAKLRWL 166
+ E+ + L+ R L IP++ +L L R N +K +P + + L+ L
Sbjct: 68 LEEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTL 127
Query: 167 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 213
LE N I+ LP + +T L NLR+ LE FP ++ K L+ +Q
Sbjct: 128 LLERNPIKMLPVELGSVTTLKALNLRHCPLE-FPPQLVVQKGLVAIQ 173
Score = 34.7 bits (76), Expect = 0.53
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 150
L NL L+L YN + L IG + L+ R +K +P E+G +T L R L
Sbjct: 98 LPNLTWLDLRYNRIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPL 157
Query: 151 KTIPE 155
+ P+
Sbjct: 158 EFPPQ 162
Score = 31.9 bits (69), Expect = 3.7
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 132 KEIGKLTQLDTFGARGNELKTIPEEMTSLA-KLRWLTLENNQIETLPDTMDRMTALVHCN 190
+E+ ++ L + N L IP++ L L WL L N+I+ LP + L
Sbjct: 69 EEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTLL 128
Query: 191 LRNNRLEQFPSSILKCKELMFLQL 214
L N ++ P + L L L
Sbjct: 129 LERNPIKMLPVELGSVTTLKALNL 152
>AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein.
Length = 988
Score = 43.2 bits (97), Expect = 0.002
Identities = 42/135 (31%), Positives = 66/135 (48%), Gaps = 8/135 (5%)
Query: 90 NLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWC--NRIGLKEIPKEIGKLTQLDTFGAR 146
+L N V++NL N L ++ L+ L+ + N++ + +G L L+ A
Sbjct: 110 HLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFLG-LESLEYLQAD 168
Query: 147 GNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE-QFPSSIL 204
N +K I +L+KLR L L +N I LP + + +L H +LR NRL+ F +L
Sbjct: 169 YNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVSLTHLDLRGNRLKVLFYRGML 228
Query: 205 K--CKELMFLQLNSN 217
+ LM LQL N
Sbjct: 229 DHIGRSLMELQLEEN 243
Score = 31.5 bits (68), Expect = 4.9
Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 5/137 (3%)
Query: 86 TEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTF 143
++ N +L L+L N ++ V +L L++ + N ++++ P L L
Sbjct: 437 SDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYL 496
Query: 144 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-S 201
N ++ I P + + L+ L L NN + TLP T+L NLR N P +
Sbjct: 497 YFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARLNLRKNYFLYLPVA 556
Query: 202 SILK-CKELMFLQLNSN 217
+L+ ++ + LN N
Sbjct: 557 GVLEHLNAIVQIDLNEN 573
>BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomerase
(cyclophilin)-like 5 protein.
Length = 414
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEM--TSLAK-LRWLTLENNQIETLPDTMDRM 183
+K++P IG L L N L++ + ++L K LR L L N+I+ LP ++
Sbjct: 189 IKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQL 248
Query: 184 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L + L +N L QFP I + L FL N+
Sbjct: 249 QELKNLKLDDNELIQFPCKIGQLINLRFLSAARNK 283
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT---QLDTFGARG 147
LK+L L+LS+N + L IGDL L+ N L+ + T L +
Sbjct: 176 LKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSK 235
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N++K +P + L +L+ L L++N++ P + ++ L + N+L PS +
Sbjct: 236 NKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSE-FRNL 294
Query: 208 ELMFLQLNSN 217
L +L L N
Sbjct: 295 SLEYLDLFGN 304
Score = 37.5 bits (83), Expect = 0.075
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
K+L +L+LS N + L + L++L+ + L + P +IG+L L A N+L
Sbjct: 226 KSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLP 285
Query: 152 TIPEEMTSLAKLRWLTLENNQIE 174
+P E +L+ L +L L N E
Sbjct: 286 FLPSEFRNLS-LEYLDLFGNTFE 307
Score = 34.3 bits (75), Expect = 0.70
Identities = 33/137 (24%), Positives = 50/137 (36%), Gaps = 5/137 (3%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV---EXXXXXXXXXXXXXXX 79
K +L L+ I ++P + + ++ L L+ N + F V
Sbjct: 177 KSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKN 236
Query: 80 XXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT- 138
P + L+ L NL L N L +IG L L R L +P E L+
Sbjct: 237 KIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSL 296
Query: 139 -QLDTFGARGNELKTIP 154
LD FG + K +P
Sbjct: 297 EYLDLFGNTFEQPKVLP 313
>AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signaling
molecule protein.
Length = 414
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 127 LKEIPKEIGKLTQLDTFGARGNELKTIPEEM--TSLAK-LRWLTLENNQIETLPDTMDRM 183
+K++P IG L L N L++ + ++L K LR L L N+I+ LP ++
Sbjct: 189 IKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQL 248
Query: 184 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQ 218
L + L +N L QFP I + L FL N+
Sbjct: 249 QELKNLKLDDNELIQFPCKIGQLINLRFLSAARNK 283
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT---QLDTFGARG 147
LK+L L+LS+N + L IGDL L+ N L+ + T L +
Sbjct: 176 LKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSK 235
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 207
N++K +P + L +L+ L L++N++ P + ++ L + N+L PS +
Sbjct: 236 NKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSE-FRNL 294
Query: 208 ELMFLQLNSN 217
L +L L N
Sbjct: 295 SLEYLDLFGN 304
Score = 37.5 bits (83), Expect = 0.075
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 92 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 151
K+L +L+LS N + L + L++L+ + L + P +IG+L L A N+L
Sbjct: 226 KSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLP 285
Query: 152 TIPEEMTSLAKLRWLTLENNQIE 174
+P E +L+ L +L L N E
Sbjct: 286 FLPSEFRNLS-LEYLDLFGNTFE 307
Score = 34.3 bits (75), Expect = 0.70
Identities = 33/137 (24%), Positives = 50/137 (36%), Gaps = 5/137 (3%)
Query: 23 KKKSRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISVFPV---EXXXXXXXXXXXXXXX 79
K +L L+ I ++P + + ++ L L+ N + F V
Sbjct: 177 KSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKN 236
Query: 80 XXXXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLT- 138
P + L+ L NL L N L +IG L L R L +P E L+
Sbjct: 237 KIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSL 296
Query: 139 -QLDTFGARGNELKTIP 154
LD FG + K +P
Sbjct: 297 EYLDLFGNTFEQPKVLP 313
>AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein.
Length = 598
Score = 42.3 bits (95), Expect = 0.003
Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Query: 91 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNE 149
L L+ L+LS+N L L P I D +EA +GL+++ + + +L L N+
Sbjct: 93 LPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQ 152
Query: 150 LKTIPEEMTSLAKLRWLTLE-NNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSI 203
L+ +P + L L L L N +I L P+ + + AL ++ N L+ P +
Sbjct: 153 LERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDL 208
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/242 (24%), Positives = 99/242 (40%), Gaps = 32/242 (13%)
Query: 8 IRENHILALIEQAIAKKKS--RLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKISVFPVE 64
++ N + + +A+ +S L L+ I+ +P ++ L + HL+L N ++ PV+
Sbjct: 121 LQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQ 180
Query: 65 XXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFW 121
+ GNL +LV L+L N ++ L + D L LE
Sbjct: 181 AFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLD 240
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGN--------------ELKTIP----------EEM 157
N L E P I L+ L N EL+T+ ++
Sbjct: 241 LNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDL 300
Query: 158 TSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
T A L LTL QI +LP T+ +++ L +L N LE PS + C++L + L
Sbjct: 301 TGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSV-CQKLQKIDLRH 359
Query: 217 NQ 218
N+
Sbjct: 360 NE 361
Score = 35.1 bits (77), Expect = 0.40
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 130 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 187
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 188 HCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
L N + P S L L L+ N
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDN 172
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/242 (24%), Positives = 99/242 (40%), Gaps = 32/242 (13%)
Query: 8 IRENHILALIEQAIAKKKS--RLSLNGFEITEIPGLLYTCLE-VEHLYLHKNKISVFPVE 64
++ N + + +A+ +S L L+ I+ +P ++ L + HL+L N ++ PV+
Sbjct: 121 LQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQ 180
Query: 65 XXXXXXXXXXXXXXXXXXXXPTE--IGNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFW 121
+ GNL +LV L+L N ++ L + D L LE
Sbjct: 181 AFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLD 240
Query: 122 CNRIGLKEIPKEIGKLTQLDTFGARGN--------------ELKTIP----------EEM 157
N L E P I L+ L N EL+T+ ++
Sbjct: 241 LNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDL 300
Query: 158 TSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 216
T A L LTL QI +LP T+ +++ L +L N LE PS + C++L + L
Sbjct: 301 TGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSV-CQKLQKIDLRH 359
Query: 217 NQ 218
N+
Sbjct: 360 NE 361
Score = 35.1 bits (77), Expect = 0.40
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 130 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 187
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 188 HCNLRNNRLEQFPSSILK-CKELMFLQLNSN 217
L N + P S L L L+ N
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDN 172
>Z24680-1|CAA80847.1| 662|Homo sapiens garp protein.
Length = 662
Score = 41.5 bits (93), Expect = 0.005
Identities = 35/110 (31%), Positives = 53/110 (48%), Gaps = 5/110 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
L L+NL+LSYN + LIP+ + L L +R L+ + +G L L
Sbjct: 314 LSQLLNLDLSYNEIE-LIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSH 372
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRL 196
N L+T+ +L LR L L+ N + LP T + +L NL+ NR+
Sbjct: 373 NALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRV 422
>BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein.
Length = 662
Score = 41.5 bits (93), Expect = 0.005
Identities = 35/110 (31%), Positives = 53/110 (48%), Gaps = 5/110 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
L L+NL+LSYN + LIP+ + L L +R L+ + +G L L
Sbjct: 314 LSQLLNLDLSYNEIE-LIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSH 372
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRL 196
N L+T+ +L LR L L+ N + LP T + +L NL+ NR+
Sbjct: 373 NALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRV 422
>BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein.
Length = 552
Score = 41.5 bits (93), Expect = 0.005
Identities = 35/110 (31%), Positives = 53/110 (48%), Gaps = 5/110 (4%)
Query: 91 LKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARG 147
L L+NL+LSYN + LIP+ + L L +R L+ + +G L L
Sbjct: 204 LSQLLNLDLSYNEIE-LIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSH 262
Query: 148 NELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRL 196
N L+T+ +L LR L L+ N + LP T + +L NL+ NR+
Sbjct: 263 NALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRV 312
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 41.5 bits (93), Expect = 0.005
Identities = 59/230 (25%), Positives = 96/230 (41%), Gaps = 16/230 (6%)
Query: 2 SAILKFIRENHILALIEQAIAKKKSR--LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKI 58
S + ++ ++IL + +A + + L LN I + PG+ L + +LYL N++
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 59 SVFP---VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL-IPEIG-- 112
S P T +G + L L+LS N N+L I E G
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVG-MVALRILDLSNN--NILRISESGFQ 201
Query: 113 DLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLEN 170
LE L + L ++P + L L N ++ I P LA L +L L+N
Sbjct: 202 HLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKN 261
Query: 171 NQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQ 218
++I + D + L H L +N LE S K L++L+L+ N+
Sbjct: 262 SRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNR 311
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 41.5 bits (93), Expect = 0.005
Identities = 59/230 (25%), Positives = 96/230 (41%), Gaps = 16/230 (6%)
Query: 2 SAILKFIRENHILALIEQAIAKKKSR--LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKI 58
S + ++ ++IL + +A + + L LN I + PG+ L + +LYL N++
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 59 SVFP---VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL-IPEIG-- 112
S P T +G + L L+LS N N+L I E G
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVG-MVALRILDLSNN--NILRISESGFQ 201
Query: 113 DLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLEN 170
LE L + L ++P + L L N ++ I P LA L +L L+N
Sbjct: 202 HLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKN 261
Query: 171 NQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQ 218
++I + D + L H L +N LE S K L++L+L+ N+
Sbjct: 262 SRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNR 311
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 41.5 bits (93), Expect = 0.005
Identities = 59/230 (25%), Positives = 96/230 (41%), Gaps = 16/230 (6%)
Query: 2 SAILKFIRENHILALIEQAIAKKKSR--LSLNGFEITEI-PGLLYTCLEVEHLYLHKNKI 58
S + ++ ++IL + +A + + L LN I + PG+ L + +LYL N++
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 59 SVFP---VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL-IPEIG-- 112
S P T +G + L L+LS N N+L I E G
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVG-MVALRILDLSNN--NILRISESGFQ 201
Query: 113 DLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLEN 170
LE L + L ++P + L L N ++ I P LA L +L L+N
Sbjct: 202 HLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKN 261
Query: 171 NQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQ 218
++I + D + L H L +N LE S K L++L+L+ N+
Sbjct: 262 SRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNR 311
>M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane
glycoprotein Ib-alpha protein.
Length = 626
Score = 41.1 bits (92), Expect = 0.006
Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 5/133 (3%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGAR 146
G L L L+LS+N L L P +G L L + L +P + L +L +
Sbjct: 90 GTLPVLGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLK 148
Query: 147 GNELKTIPEE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL 204
GNELKT+P +T KL L+L NN + LP ++ + L L+ N L P
Sbjct: 149 GNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Query: 205 KCKELMFLQLNSN 217
L F L+ N
Sbjct: 209 GSHLLPFAFLHGN 221
>J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein.
Length = 626
Score = 41.1 bits (92), Expect = 0.006
Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 5/133 (3%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGAR 146
G L L L+LS+N L L P +G L L + L +P + L +L +
Sbjct: 90 GTLPVLGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLK 148
Query: 147 GNELKTIPEE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL 204
GNELKT+P +T KL L+L NN + LP ++ + L L+ N L P
Sbjct: 149 GNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Query: 205 KCKELMFLQLNSN 217
L F L+ N
Sbjct: 209 GSHLLPFAFLHGN 221
>BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib
(platelet), alpha polypeptide protein.
Length = 626
Score = 41.1 bits (92), Expect = 0.006
Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 5/133 (3%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGAR 146
G L L L+LS+N L L P +G L L + L +P + L +L +
Sbjct: 90 GTLPVLGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLK 148
Query: 147 GNELKTIPEE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL 204
GNELKT+P +T KL L+L NN + LP ++ + L L+ N L P
Sbjct: 149 GNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Query: 205 KCKELMFLQLNSN 217
L F L+ N
Sbjct: 209 GSHLLPFAFLHGN 221
>AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein.
Length = 627
Score = 41.1 bits (92), Expect = 0.006
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 6/95 (6%)
Query: 89 GNLKNLVNLN---LSYNPLNVLIPEIGD--LEKLEAFWCNRIGLKEIPKE-IGKLTQLDT 142
G L+ LVNL LS N L L D E LE + L+++P E +G+L ++T
Sbjct: 125 GQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNVNT 184
Query: 143 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP 177
G N L ++P + L KL L + +N++ T+P
Sbjct: 185 LGLDHNLLASVPGAFSRLHKLARLDMTSNRLTTIP 219
Score = 30.7 bits (66), Expect = 8.6
Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 148 NELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 200
N L+ +P E + L + L L++N + ++P R+ L ++ +NRL P
Sbjct: 166 NNLEQLPWEALGRLGNVNTLGLDHNLLASVPGAFSRLHKLARLDMTSNRLTTIP 219
>AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein Ib
alpha polypeptide protein.
Length = 639
Score = 41.1 bits (92), Expect = 0.006
Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 5/133 (3%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGAR 146
G L L L+LS+N L L P +G L L + L +P + L +L +
Sbjct: 90 GTLPVLGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLK 148
Query: 147 GNELKTIPEE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL 204
GNELKT+P +T KL L+L NN + LP ++ + L L+ N L P
Sbjct: 149 GNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Query: 205 KCKELMFLQLNSN 217
L F L+ N
Sbjct: 209 GSHLLPFAFLHGN 221
>AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib
(platelet), alpha polypeptide protein.
Length = 626
Score = 41.1 bits (92), Expect = 0.006
Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 5/133 (3%)
Query: 89 GNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGAR 146
G L L L+LS+N L L P +G L L + L +P + L +L +
Sbjct: 90 GTLPVLGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLK 148
Query: 147 GNELKTIPEE-MTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL 204
GNELKT+P +T KL L+L NN + LP ++ + L L+ N L P
Sbjct: 149 GNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Query: 205 KCKELMFLQLNSN 217
L F L+ N
Sbjct: 209 GSHLLPFAFLHGN 221
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.316 0.134 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 46,639,970
Number of Sequences: 224733
Number of extensions: 1692145
Number of successful extensions: 6753
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 200
Number of HSP's successfully gapped in prelim test: 304
Number of HSP's that attempted gapping in prelim test: 4131
Number of HSP's gapped (non-prelim): 1859
length of query: 370
length of database: 73,234,838
effective HSP length: 91
effective length of query: 279
effective length of database: 52,784,135
effective search space: 14726773665
effective search space used: 14726773665
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 66 (30.7 bits)
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