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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000125-TA|BGIBMGA000125-PA|IPR013520|Exonuclease, RNase
T and DNA polymerase III, IPR006055|Exonuclease,
IPR012337|Polynucleotidyl transferase, Ribonuclease H fold
         (300 letters)

Database: fruitfly 
           52,641 sequences; 24,830,863 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY070563-1|AAL48034.1|  351|Drosophila melanogaster LD40940p pro...   115   7e-26
AE014134-526|AAF51172.1|  351|Drosophila melanogaster CG3165-PA ...   115   7e-26
AY051876-1|AAK93300.1|  395|Drosophila melanogaster LD37002p pro...    33   0.36 
AE014297-3579|AAF56317.1|  395|Drosophila melanogaster CG13626-P...    33   0.36 
AF146594-1|AAD38688.1| 1377|Drosophila melanogaster protein tyro...    31   1.5  
AE014297-4072|AAF56669.1|  463|Drosophila melanogaster CG6066-PA...    31   1.5  
AE013599-3236|AAF46739.2| 1377|Drosophila melanogaster CG9856-PA...    31   1.5  
AY051925-1|AAK93349.1|  587|Drosophila melanogaster LD40944p pro...    31   2.6  
AE013599-1214|AAF58715.1|  587|Drosophila melanogaster CG12391-P...    31   2.6  
AF220354-1|AAF32356.1| 1931|Drosophila melanogaster mitotic kine...    30   3.4  
AE014134-2054|AAF53089.2| 1931|Drosophila melanogaster CG33694-P...    30   3.4  
X14037-1|CAA32198.1| 1053|Drosophila melanogaster polyprotein pr...    29   5.9  
BT003485-1|AAO39488.1|  328|Drosophila melanogaster SD13756p pro...    29   5.9  
BT001493-1|AAN71248.1|  864|Drosophila melanogaster LD30051p pro...    29   5.9  
AY069780-1|AAL39925.1|  741|Drosophila melanogaster SD02338p pro...    29   7.8  
AY069301-1|AAL39446.1|  518|Drosophila melanogaster HL03404p pro...    29   7.8  
AE014296-1148|AAN12081.1| 2465|Drosophila melanogaster CG32394-P...    29   7.8  
AE014296-515|AAF47691.2| 2252|Drosophila melanogaster CG2083-PA ...    29   7.8  
AE013599-1757|AAF58345.1|  607|Drosophila melanogaster CG6209-PA...    29   7.8  

>AY070563-1|AAL48034.1|  351|Drosophila melanogaster LD40940p
           protein.
          Length = 351

 Score =  115 bits (277), Expect = 7e-26
 Identities = 97/326 (29%), Positives = 145/326 (44%), Gaps = 32/326 (9%)

Query: 3   RITTYVFFDIETTGLPFQERNKTKITELCFLAVS---------RDDLDIQSGLPP----I 49
           +I+T+   D+ETT LP    N+  ITELC  A             D D Q  LP     +
Sbjct: 16  KISTFAVLDLETTNLPAYRNNRVSITELCIYAFEAALLKKKKKEQDQDEQQELPAAPRVL 75

Query: 50  KKLSFVLNPEKKIHPDVVVLTGLTNESLKNAPTFK-QRANAIVSFLNELPKPICLVAHNG 108
            KL+ +  P   + P+   +TGL+N  L+         A  IVSFL  LP P+CLVAHNG
Sbjct: 76  HKLNVLFQPSMVVDPEAERITGLSNYLLERESQLDTDAAQLIVSFLKHLPSPVCLVAHNG 135

Query: 109 NSFDYKILLAECNDAGILLPSDLLCIDSLIGFRKILKTTQK-SLPLKMNTSKDDSASELL 167
             FD+ IL        I LP  L C+DSL  F +I  T QK +  LK+     +   EL 
Sbjct: 136 WGFDFPILRQAFEKLNIELPQSLTCVDSLRAFMEIDDTQQKETSQLKVPNDVQEIIPELK 195

Query: 168 WPELDVST--ENWEEIDNLCASFSKDTCIDD---------EKSKKENDLNQQKCTNLKKG 216
            P+ +  T  +  E + N+      +T  +           K K   D ++         
Sbjct: 196 -PKQNTETCLKEPEAVVNIDWRTRNETTPNRPILKPTEAFAKRKLLRDGDEDDLEEQTPP 254

Query: 217 RKNKNDLTTQDQSLS----IQNKSTKKR-EFTLTGLYKRLLDKDAVNAHRAEDDCVILIE 271
           ++  ++  ++ Q  S     +NK    R  + L  LY R+    A++AH+AE D V+  +
Sbjct: 255 KRKPDEFRSRRQLFSGCKCAENKRYPPRGVYNLESLYTRIFKIPALSAHQAEADVVMTTK 314

Query: 272 CVLALRDEFLTWADESCKTIHQIKPL 297
            +     +FL +A+E      Q+ PL
Sbjct: 315 LIQHYGIDFLAFAEEQAIPFQQVVPL 340


>AE014134-526|AAF51172.1|  351|Drosophila melanogaster CG3165-PA
           protein.
          Length = 351

 Score =  115 bits (277), Expect = 7e-26
 Identities = 97/326 (29%), Positives = 145/326 (44%), Gaps = 32/326 (9%)

Query: 3   RITTYVFFDIETTGLPFQERNKTKITELCFLAVS---------RDDLDIQSGLPP----I 49
           +I+T+   D+ETT LP    N+  ITELC  A             D D Q  LP     +
Sbjct: 16  KISTFAVLDLETTNLPAYRNNRVSITELCIYAFEAALLKKKKKEQDQDEQQELPAAPRVL 75

Query: 50  KKLSFVLNPEKKIHPDVVVLTGLTNESLKNAPTFK-QRANAIVSFLNELPKPICLVAHNG 108
            KL+ +  P   + P+   +TGL+N  L+         A  IVSFL  LP P+CLVAHNG
Sbjct: 76  HKLNVLFQPSMVVDPEAERITGLSNYLLERESQLDTDAAQLIVSFLKHLPSPVCLVAHNG 135

Query: 109 NSFDYKILLAECNDAGILLPSDLLCIDSLIGFRKILKTTQK-SLPLKMNTSKDDSASELL 167
             FD+ IL        I LP  L C+DSL  F +I  T QK +  LK+     +   EL 
Sbjct: 136 WGFDFPILRQAFEKLNIELPQSLTCVDSLRAFMEIDDTQQKETSQLKVPNDVQEIIPELK 195

Query: 168 WPELDVST--ENWEEIDNLCASFSKDTCIDD---------EKSKKENDLNQQKCTNLKKG 216
            P+ +  T  +  E + N+      +T  +           K K   D ++         
Sbjct: 196 -PKQNTETCLKEPEAVVNIDWRTRNETTPNRPILKPTEAFAKRKLLRDGDEDDLEEQTPP 254

Query: 217 RKNKNDLTTQDQSLS----IQNKSTKKR-EFTLTGLYKRLLDKDAVNAHRAEDDCVILIE 271
           ++  ++  ++ Q  S     +NK    R  + L  LY R+    A++AH+AE D V+  +
Sbjct: 255 KRKPDEFRSRRQLFSGCKCAENKRYPPRGVYNLESLYTRIFKIPALSAHQAEADVVMTTK 314

Query: 272 CVLALRDEFLTWADESCKTIHQIKPL 297
            +     +FL +A+E      Q+ PL
Sbjct: 315 LIQHYGIDFLAFAEEQAIPFQQVVPL 340


>AY051876-1|AAK93300.1|  395|Drosophila melanogaster LD37002p
           protein.
          Length = 395

 Score = 33.5 bits (73), Expect = 0.36
 Identities = 13/47 (27%), Positives = 25/47 (53%)

Query: 195 DDEKSKKENDLNQQKCTNLKKGRKNKNDLTTQDQSLSIQNKSTKKRE 241
           D EK K+ N  NQ K    K+ + N++DL      +++  +  +++E
Sbjct: 234 DGEKGKEANQANQHKPRTRKRSKANRSDLNNSSSKMALDEELQQQQE 280


>AE014297-3579|AAF56317.1|  395|Drosophila melanogaster CG13626-PA
           protein.
          Length = 395

 Score = 33.5 bits (73), Expect = 0.36
 Identities = 13/47 (27%), Positives = 25/47 (53%)

Query: 195 DDEKSKKENDLNQQKCTNLKKGRKNKNDLTTQDQSLSIQNKSTKKRE 241
           D EK K+ N  NQ K    K+ + N++DL      +++  +  +++E
Sbjct: 234 DGEKGKEANQANQHKPRTRKRSKANRSDLNNSSSKMALDEELQQQQE 280


>AF146594-1|AAD38688.1| 1377|Drosophila melanogaster protein
           tyrosine phosphatase ERK protein.
          Length = 1377

 Score = 31.5 bits (68), Expect = 1.5
 Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 3/69 (4%)

Query: 168 WPELDVSTENWEEIDNLCASFSKDTCIDDEKSKKENDLNQQKCTNLKKGRKNKNDLTTQD 227
           +PE+D   ++   +D +C    + T  D   +  E    QQ+ +  +K RKNKN+LT + 
Sbjct: 232 FPEIDHVVQD-APMDTVC--LEEATRRDRSPALAEPPEQQQQKSEGRKNRKNKNNLTIRI 288

Query: 228 QSLSIQNKS 236
             + I+N S
Sbjct: 289 TDVPIKNSS 297


>AE014297-4072|AAF56669.1|  463|Drosophila melanogaster CG6066-PA
           protein.
          Length = 463

 Score = 31.5 bits (68), Expect = 1.5
 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 5/104 (4%)

Query: 139 GFRKILKTTQKSLPLKMNTSKDDSASELLWPELDVSTENWEEIDNLCASFSKDTCIDDEK 198
           G RK  K+ +KS      + K  S  E        S+ + E+  +  +S S  +  D E 
Sbjct: 215 GKRKHKKSEKKSKKKSKKSKKKKSKQE---SSSSSSSSSSEDSSDESSSSSSSSSSDSED 271

Query: 199 SKKENDLNQQKCTN-LKKGRKNKNDLTTQDQSLSIQNKSTKKRE 241
             +E D+  +K  + +KK +K K+  + +D+  S + K  +K E
Sbjct: 272 ESEEEDVWLEKTADGIKKPKKKKSSTSKKDKK-SKKKKKKRKSE 314


>AE013599-3236|AAF46739.2| 1377|Drosophila melanogaster CG9856-PA
           protein.
          Length = 1377

 Score = 31.5 bits (68), Expect = 1.5
 Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 3/69 (4%)

Query: 168 WPELDVSTENWEEIDNLCASFSKDTCIDDEKSKKENDLNQQKCTNLKKGRKNKNDLTTQD 227
           +PE+D   ++   +D +C    + T  D   +  E    QQ+ +  +K RKNKN+LT + 
Sbjct: 232 FPEIDHVVQD-APMDTVC--LEEATRRDRSPALAEPPEQQQQKSEGRKNRKNKNNLTIRI 288

Query: 228 QSLSIQNKS 236
             + I+N S
Sbjct: 289 TDVPIKNSS 297


>AY051925-1|AAK93349.1|  587|Drosophila melanogaster LD40944p
           protein.
          Length = 587

 Score = 30.7 bits (66), Expect = 2.6
 Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 16/155 (10%)

Query: 101 ICLVAHNGNSFDYKILLAECNDAGILLPSDLL-------CIDSL---IGFRKILKTTQKS 150
           +CL     ++    +LL  C +  IL P D +       C+ SL   I  RK L+TT + 
Sbjct: 251 VCLFKKQIDATPADMLLVICPNVSIL-PKDFMPQFICTKCMGSLTIAIQLRKQLETTDQE 309

Query: 151 LPLKMNTSKDDSASELLWPELDV----STENWEEIDN-LCASFSKDTCIDDEKSKKENDL 205
           L  +++ SK+       +  +D     S+E+ +E+D+    S    T   D  S   +D 
Sbjct: 310 LRKRLSRSKNKVRRPRGYVVIDAPVTDSSEDEDELDDEFKVSDVAGTTSADSDSADSDDS 369

Query: 206 NQQKCTNLKKGRKNKNDLTTQDQSLSIQNKSTKKR 240
            ++K     +GR  K  L     S    + + KK+
Sbjct: 370 EKEKKKPGPRGRPRKKPLKRGTDSDGEPSSAQKKK 404


>AE013599-1214|AAF58715.1|  587|Drosophila melanogaster CG12391-PA
           protein.
          Length = 587

 Score = 30.7 bits (66), Expect = 2.6
 Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 16/155 (10%)

Query: 101 ICLVAHNGNSFDYKILLAECNDAGILLPSDLL-------CIDSL---IGFRKILKTTQKS 150
           +CL     ++    +LL  C +  IL P D +       C+ SL   I  RK L+TT + 
Sbjct: 251 VCLFKKQIDATPADMLLVICPNVSIL-PKDFMPQFICTKCMGSLTIAIQLRKQLETTDQE 309

Query: 151 LPLKMNTSKDDSASELLWPELDV----STENWEEIDN-LCASFSKDTCIDDEKSKKENDL 205
           L  +++ SK+       +  +D     S+E+ +E+D+    S    T   D  S   +D 
Sbjct: 310 LRKRLSRSKNKVRRPRGYVVIDAPVTDSSEDEDELDDEFKVSDVAGTTSADSDSADSDDS 369

Query: 206 NQQKCTNLKKGRKNKNDLTTQDQSLSIQNKSTKKR 240
            ++K     +GR  K  L     S    + + KK+
Sbjct: 370 EKEKKKPGPRGRPRKKPLKRGTDSDGEPSSAQKKK 404


>AF220354-1|AAF32356.1| 1931|Drosophila melanogaster mitotic
            kinesin-like motor proteinCENP-ana protein.
          Length = 1931

 Score = 30.3 bits (65), Expect = 3.4
 Identities = 15/56 (26%), Positives = 34/56 (60%)

Query: 214  KKGRKNKNDLTTQDQSLSIQNKSTKKREFTLTGLYKRLLDKDAVNAHRAEDDCVIL 269
            + G + ++  TT ++SL+++    ++ E TLT  Y+R +++   +  RA+++  IL
Sbjct: 1078 ESGVELQHHSTTAEESLNVEKPIQEQTERTLTTEYERRIEQLEESLQRAQEELSIL 1133


>AE014134-2054|AAF53089.2| 1931|Drosophila melanogaster CG33694-PA,
            isoform A protein.
          Length = 1931

 Score = 30.3 bits (65), Expect = 3.4
 Identities = 15/56 (26%), Positives = 34/56 (60%)

Query: 214  KKGRKNKNDLTTQDQSLSIQNKSTKKREFTLTGLYKRLLDKDAVNAHRAEDDCVIL 269
            + G + ++  TT ++SL+++    ++ E TLT  Y+R +++   +  RA+++  IL
Sbjct: 1078 ESGVELQHHSTTAEESLNVEKPIQEQTERTLTTEYERRIEQLEESLQRAQEELSIL 1133


>X14037-1|CAA32198.1| 1053|Drosophila melanogaster polyprotein
           protein.
          Length = 1053

 Score = 29.5 bits (63), Expect = 5.9
 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 2/43 (4%)

Query: 62  IHPDVVVLTGLTNESLKNAPTFKQRANAIVSFLNELPKPICLV 104
           IHP+ V  T    + LKNAP+  QR   +++ L +L     +V
Sbjct: 557 IHPESVEYTAFVPDGLKNAPSVFQR--TVINALGDLANSFVIV 597


>BT003485-1|AAO39488.1|  328|Drosophila melanogaster SD13756p
           protein.
          Length = 328

 Score = 29.5 bits (63), Expect = 5.9
 Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 4/98 (4%)

Query: 139 GFRKILKTTQKSLPLKMNTSKDDSASELLWPELDVSTENWEEIDNLCASFSKDTCIDDEK 198
           G RK  K+ +KS      + K  S  E        S+ + E+  +  +S S  +  D E 
Sbjct: 233 GKRKHKKSEKKSKKKSKKSKKKKSKQE---SSSSSSSSSSEDSSDESSSSSSSSSSDSED 289

Query: 199 SKKENDLNQQKCTN-LKKGRKNKNDLTTQDQSLSIQNK 235
             +E D+  +K  + +KK +K K+  + +D+    + K
Sbjct: 290 ESEEEDVWLEKTADGIKKPKKKKSSTSKKDKKSKKKKK 327


>BT001493-1|AAN71248.1|  864|Drosophila melanogaster LD30051p
           protein.
          Length = 864

 Score = 29.5 bits (63), Expect = 5.9
 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 11/94 (11%)

Query: 150 SLPLKMNTSKDDSASELLWPELDVSTENWEEIDNLCASFSKDTCIDDEKSKK--ENDLNQ 207
           SLPL  N  ++         ++D   EN E+ +N   + ++D+   D K  K  E D+ +
Sbjct: 11  SLPLPQNNDEEQ--------KIDTVAENEEDQENTQLTDARDSHEKDRKPSKERERDIEK 62

Query: 208 QKCTNLKKGRKNKNDLTTQDQSLSIQNKSTKKRE 241
           +K   LK+  K K+    +D+      + +K+R+
Sbjct: 63  KKIRELKR-EKIKDRDRDRDRDREKDKEKSKERD 95


>AY069780-1|AAL39925.1|  741|Drosophila melanogaster SD02338p
           protein.
          Length = 741

 Score = 29.1 bits (62), Expect = 7.8
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 8/87 (9%)

Query: 154 KMNTSKDDSASELLWPELDVSTENWEEIDNLCASFSKDTCIDDEKS--KKENDLNQQKCT 211
           K+NT  D+ A E    E  +     E++D L     +D  + DE    KKE+  N Q+  
Sbjct: 567 KINTDLDNKAKEER--ERLIKKAAGEDMDEL----DEDALMQDEPVPIKKESSANGQQLK 620

Query: 212 NLKKGRKNKNDLTTQDQSLSIQNKSTK 238
           N   G K K    ++    + Q+K+ K
Sbjct: 621 NGASGSKKKKSSDSKKSQANEQSKNEK 647


>AY069301-1|AAL39446.1|  518|Drosophila melanogaster HL03404p
           protein.
          Length = 518

 Score = 29.1 bits (62), Expect = 7.8
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 8/87 (9%)

Query: 154 KMNTSKDDSASELLWPELDVSTENWEEIDNLCASFSKDTCIDDEKS--KKENDLNQQKCT 211
           K+NT  D+ A E    E  +     E++D L     +D  + DE    KKE+  N Q+  
Sbjct: 344 KINTDLDNKAKEER--ERLIKKAAGEDMDEL----DEDALMQDEPVPIKKESSANGQQLK 397

Query: 212 NLKKGRKNKNDLTTQDQSLSIQNKSTK 238
           N   G K K    ++    + Q+K+ K
Sbjct: 398 NGASGSKKKKSSDSKKSQANEQSKNEK 424


>AE014296-1148|AAN12081.1| 2465|Drosophila melanogaster CG32394-PA
           protein.
          Length = 2465

 Score = 29.1 bits (62), Expect = 7.8
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 5/45 (11%)

Query: 195 DDEKSKKENDLNQQKCTNLKKGRKNKNDLTTQDQSLSIQNKSTKK 239
           D EK K ++    ++ ++ K+GRK K+D     +S S  +K TKK
Sbjct: 360 DKEKEKDKDKEKDKETSSFKRGRKTKSD-----KSASKSSKKTKK 399


>AE014296-515|AAF47691.2| 2252|Drosophila melanogaster CG2083-PA
            protein.
          Length = 2252

 Score = 29.1 bits (62), Expect = 7.8
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 8/87 (9%)

Query: 154  KMNTSKDDSASELLWPELDVSTENWEEIDNLCASFSKDTCIDDEKS--KKENDLNQQKCT 211
            K+NT  D+ A E    E  +     E++D L     +D  + DE    KKE+  N Q+  
Sbjct: 2078 KINTDLDNKAKEER--ERLIKKAAGEDMDEL----DEDALMQDEPVPIKKESSANGQQLK 2131

Query: 212  NLKKGRKNKNDLTTQDQSLSIQNKSTK 238
            N   G K K    ++    + Q+K+ K
Sbjct: 2132 NGASGSKKKKSSDSKKSQANEQSKNEK 2158


>AE013599-1757|AAF58345.1|  607|Drosophila melanogaster CG6209-PA
           protein.
          Length = 607

 Score = 29.1 bits (62), Expect = 7.8
 Identities = 12/50 (24%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 193 CID-DEKSKKENDLNQQKCTNLKKGRKNKNDLTTQDQSLSIQNKSTKKRE 241
           C++ D K    ND   +KC   KK +  + +  T+ +  ++Q K  + ++
Sbjct: 510 CVESDRKKNSANDAAMKKCEEDKKKKSQEAEKKTKSEQAALQKKCAEAKK 559


  Database: fruitfly
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 24,830,863
  Number of sequences in database:  52,641
  
Lambda     K      H
   0.317    0.134    0.392 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 14,812,672
Number of Sequences: 52641
Number of extensions: 643875
Number of successful extensions: 2055
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2032
Number of HSP's gapped (non-prelim): 32
length of query: 300
length of database: 24,830,863
effective HSP length: 85
effective length of query: 215
effective length of database: 20,356,378
effective search space: 4376621270
effective search space used: 4376621270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 62 (29.1 bits)

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