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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000121-TA|BGIBMGA000121-
PA|IPR007704|Mannosyltransferase, DXD
         (428 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC019865-1|AAH19865.1|  423|Homo sapiens phosphatidylinositol gl...   265   2e-70
BC001803-1|AAH01803.1|  423|Homo sapiens phosphatidylinositol gl...   265   2e-70
AL513302-2|CAH71492.1|  423|Homo sapiens phosphatidylinositol gl...   265   2e-70
AK074655-1|BAC11116.1|  423|Homo sapiens protein ( Homo sapiens ...   265   2e-70
AB028127-1|BAB18567.1|  423|Homo sapiens mannosyltransferase pro...   265   2e-70

>BC019865-1|AAH19865.1|  423|Homo sapiens phosphatidylinositol
           glycan anchor biosynthesis, class M protein.
          Length = 423

 Score =  265 bits (649), Expect = 2e-70
 Identities = 151/404 (37%), Positives = 218/404 (53%), Gaps = 25/404 (6%)

Query: 18  IGLTVRLVFILYGNIHDRFSVVPYTDVDYKVFTDAARHLVEGNSPYLRHTYRYSPLIAYL 77
           +    R+  + YG   DR   V YTD+DY+VFTDAAR + EG SPYLR TYRY+PL+ +L
Sbjct: 24  VAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWL 83

Query: 78  MIPNIIVGREFGKILFSVFDIFLAAAV-KSLVERQLGVAKYASVTAKYCALSWLYNPLSI 136
           + PNI +   FGK LF   D+  A  + + L+ + LG  +       YC   WL NPL +
Sbjct: 84  LTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQ----ACGYCVF-WLLNPLPM 138

Query: 137 GISTRGNADSFPCFLIVLSIYFLQSNVFKNSITNIVLSGFFLGSAIHLRLYPLAFTFPMY 196
            +S+RGNADS    L+++ +Y ++  +       +  +  F G A+H+++YP+ +  P+ 
Sbjct: 139 AVSSRGNADSIVASLVLMVLYLIKKRL-------VACAAVFYGFAVHMKIYPVTYILPIT 191

Query: 197 LSLGKYKINRNT------PIKEGLVSLLPNK-NQMILAFSCVTSLLF--ITYAMYLRYGY 247
           L L   + N  +        +  L  LL    N+ +L F  V  L F  +++  Y  YG+
Sbjct: 192 LHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGW 251

Query: 248 EFLFETYIYHLLRKDTRHNFSILFYYTYLTKDQMSFDIVKILAQVSKCVLLFLLSLNYGC 307
           EFL  TY YHL R+D RHNFS  FY  YLT +      + I A + + +LL  +S  Y  
Sbjct: 252 EFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFAYYR 311

Query: 308 DPKTLPFAMFAQAVVLVAYNSVMTSQYFIWFLSLLPLVLKDFKMEPGKIVYLVFLWIATQ 367
           D   L F  F    + V +N V TSQYF+W+L LLPLV+   +M   + V L+ LW   Q
Sbjct: 312 D---LVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQ 368

Query: 368 CAWLFFAYQLEFKCRQVFMLIWCQSVMFYGSNVFILTQLIKYYR 411
             WL  AY LEF+ +  F+ IW   + F   N  IL Q+I +Y+
Sbjct: 369 AMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYK 412


>BC001803-1|AAH01803.1|  423|Homo sapiens phosphatidylinositol
           glycan anchor biosynthesis, class M protein.
          Length = 423

 Score =  265 bits (649), Expect = 2e-70
 Identities = 151/404 (37%), Positives = 218/404 (53%), Gaps = 25/404 (6%)

Query: 18  IGLTVRLVFILYGNIHDRFSVVPYTDVDYKVFTDAARHLVEGNSPYLRHTYRYSPLIAYL 77
           +    R+  + YG   DR   V YTD+DY+VFTDAAR + EG SPYLR TYRY+PL+ +L
Sbjct: 24  VAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWL 83

Query: 78  MIPNIIVGREFGKILFSVFDIFLAAAV-KSLVERQLGVAKYASVTAKYCALSWLYNPLSI 136
           + PNI +   FGK LF   D+  A  + + L+ + LG  +       YC   WL NPL +
Sbjct: 84  LTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQ----ACGYCVF-WLLNPLPM 138

Query: 137 GISTRGNADSFPCFLIVLSIYFLQSNVFKNSITNIVLSGFFLGSAIHLRLYPLAFTFPMY 196
            +S+RGNADS    L+++ +Y ++  +       +  +  F G A+H+++YP+ +  P+ 
Sbjct: 139 AVSSRGNADSIVASLVLMVLYLIKKRL-------VACAAVFYGFAVHMKIYPVTYILPIT 191

Query: 197 LSLGKYKINRNT------PIKEGLVSLLPNK-NQMILAFSCVTSLLF--ITYAMYLRYGY 247
           L L   + N  +        +  L  LL    N+ +L F  V  L F  +++  Y  YG+
Sbjct: 192 LHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGW 251

Query: 248 EFLFETYIYHLLRKDTRHNFSILFYYTYLTKDQMSFDIVKILAQVSKCVLLFLLSLNYGC 307
           EFL  TY YHL R+D RHNFS  FY  YLT +      + I A + + +LL  +S  Y  
Sbjct: 252 EFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFAYYR 311

Query: 308 DPKTLPFAMFAQAVVLVAYNSVMTSQYFIWFLSLLPLVLKDFKMEPGKIVYLVFLWIATQ 367
           D   L F  F    + V +N V TSQYF+W+L LLPLV+   +M   + V L+ LW   Q
Sbjct: 312 D---LVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQ 368

Query: 368 CAWLFFAYQLEFKCRQVFMLIWCQSVMFYGSNVFILTQLIKYYR 411
             WL  AY LEF+ +  F+ IW   + F   N  IL Q+I +Y+
Sbjct: 369 AMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYK 412


>AL513302-2|CAH71492.1|  423|Homo sapiens phosphatidylinositol
           glycan anchor biosynthesis, class M protein.
          Length = 423

 Score =  265 bits (649), Expect = 2e-70
 Identities = 151/404 (37%), Positives = 218/404 (53%), Gaps = 25/404 (6%)

Query: 18  IGLTVRLVFILYGNIHDRFSVVPYTDVDYKVFTDAARHLVEGNSPYLRHTYRYSPLIAYL 77
           +    R+  + YG   DR   V YTD+DY+VFTDAAR + EG SPYLR TYRY+PL+ +L
Sbjct: 24  VAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWL 83

Query: 78  MIPNIIVGREFGKILFSVFDIFLAAAV-KSLVERQLGVAKYASVTAKYCALSWLYNPLSI 136
           + PNI +   FGK LF   D+  A  + + L+ + LG  +       YC   WL NPL +
Sbjct: 84  LTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQ----ACGYCVF-WLLNPLPM 138

Query: 137 GISTRGNADSFPCFLIVLSIYFLQSNVFKNSITNIVLSGFFLGSAIHLRLYPLAFTFPMY 196
            +S+RGNADS    L+++ +Y ++  +       +  +  F G A+H+++YP+ +  P+ 
Sbjct: 139 AVSSRGNADSIVASLVLMVLYLIKKRL-------VACAAVFYGFAVHMKIYPVTYILPIT 191

Query: 197 LSLGKYKINRNT------PIKEGLVSLLPNK-NQMILAFSCVTSLLF--ITYAMYLRYGY 247
           L L   + N  +        +  L  LL    N+ +L F  V  L F  +++  Y  YG+
Sbjct: 192 LHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGW 251

Query: 248 EFLFETYIYHLLRKDTRHNFSILFYYTYLTKDQMSFDIVKILAQVSKCVLLFLLSLNYGC 307
           EFL  TY YHL R+D RHNFS  FY  YLT +      + I A + + +LL  +S  Y  
Sbjct: 252 EFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFAYYR 311

Query: 308 DPKTLPFAMFAQAVVLVAYNSVMTSQYFIWFLSLLPLVLKDFKMEPGKIVYLVFLWIATQ 367
           D   L F  F    + V +N V TSQYF+W+L LLPLV+   +M   + V L+ LW   Q
Sbjct: 312 D---LVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQ 368

Query: 368 CAWLFFAYQLEFKCRQVFMLIWCQSVMFYGSNVFILTQLIKYYR 411
             WL  AY LEF+ +  F+ IW   + F   N  IL Q+I +Y+
Sbjct: 369 AMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYK 412


>AK074655-1|BAC11116.1|  423|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90174 fis, clone MAMMA1000473, highly similar to
           PIG-M mannosyltransferase. ).
          Length = 423

 Score =  265 bits (649), Expect = 2e-70
 Identities = 151/404 (37%), Positives = 218/404 (53%), Gaps = 25/404 (6%)

Query: 18  IGLTVRLVFILYGNIHDRFSVVPYTDVDYKVFTDAARHLVEGNSPYLRHTYRYSPLIAYL 77
           +    R+  + YG   DR   V YTD+DY+VFTDAAR + EG SPYLR TYRY+PL+ +L
Sbjct: 24  VAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWL 83

Query: 78  MIPNIIVGREFGKILFSVFDIFLAAAV-KSLVERQLGVAKYASVTAKYCALSWLYNPLSI 136
           + PNI +   FGK LF   D+  A  + + L+ + LG  +       YC   WL NPL +
Sbjct: 84  LTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQ----ACGYCVF-WLLNPLPM 138

Query: 137 GISTRGNADSFPCFLIVLSIYFLQSNVFKNSITNIVLSGFFLGSAIHLRLYPLAFTFPMY 196
            +S+RGNADS    L+++ +Y ++  +       +  +  F G A+H+++YP+ +  P+ 
Sbjct: 139 AVSSRGNADSIVASLVLMVLYLIKKRL-------VACAAVFYGFAVHMKIYPVTYILPIT 191

Query: 197 LSLGKYKINRNT------PIKEGLVSLLPNK-NQMILAFSCVTSLLF--ITYAMYLRYGY 247
           L L   + N  +        +  L  LL    N+ +L F  V  L F  +++  Y  YG+
Sbjct: 192 LHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGW 251

Query: 248 EFLFETYIYHLLRKDTRHNFSILFYYTYLTKDQMSFDIVKILAQVSKCVLLFLLSLNYGC 307
           EFL  TY YHL R+D RHNFS  FY  YLT +      + I A + + +LL  +S  Y  
Sbjct: 252 EFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFAYYR 311

Query: 308 DPKTLPFAMFAQAVVLVAYNSVMTSQYFIWFLSLLPLVLKDFKMEPGKIVYLVFLWIATQ 367
           D   L F  F    + V +N V TSQYF+W+L LLPLV+   +M   + V L+ LW   Q
Sbjct: 312 D---LVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQ 368

Query: 368 CAWLFFAYQLEFKCRQVFMLIWCQSVMFYGSNVFILTQLIKYYR 411
             WL  AY LEF+ +  F+ IW   + F   N  IL Q+I +Y+
Sbjct: 369 AMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYK 412


>AB028127-1|BAB18567.1|  423|Homo sapiens mannosyltransferase
           protein.
          Length = 423

 Score =  265 bits (649), Expect = 2e-70
 Identities = 151/404 (37%), Positives = 218/404 (53%), Gaps = 25/404 (6%)

Query: 18  IGLTVRLVFILYGNIHDRFSVVPYTDVDYKVFTDAARHLVEGNSPYLRHTYRYSPLIAYL 77
           +    R+  + YG   DR   V YTD+DY+VFTDAAR + EG SPYLR TYRY+PL+ +L
Sbjct: 24  VAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWL 83

Query: 78  MIPNIIVGREFGKILFSVFDIFLAAAV-KSLVERQLGVAKYASVTAKYCALSWLYNPLSI 136
           + PNI +   FGK LF   D+  A  + + L+ + LG  +       YC   WL NPL +
Sbjct: 84  LTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQ----ACGYCVF-WLLNPLPM 138

Query: 137 GISTRGNADSFPCFLIVLSIYFLQSNVFKNSITNIVLSGFFLGSAIHLRLYPLAFTFPMY 196
            +S+RGNADS    L+++ +Y ++  +       +  +  F G A+H+++YP+ +  P+ 
Sbjct: 139 AVSSRGNADSIVASLVLMVLYLIKKRL-------VACAAVFYGFAVHMKIYPVTYILPIT 191

Query: 197 LSLGKYKINRNT------PIKEGLVSLLPNK-NQMILAFSCVTSLLF--ITYAMYLRYGY 247
           L L   + N  +        +  L  LL    N+ +L F  V  L F  +++  Y  YG+
Sbjct: 192 LHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGW 251

Query: 248 EFLFETYIYHLLRKDTRHNFSILFYYTYLTKDQMSFDIVKILAQVSKCVLLFLLSLNYGC 307
           EFL  TY YHL R+D RHNFS  FY  YLT +      + I A + + +LL  +S  Y  
Sbjct: 252 EFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFAYYR 311

Query: 308 DPKTLPFAMFAQAVVLVAYNSVMTSQYFIWFLSLLPLVLKDFKMEPGKIVYLVFLWIATQ 367
           D   L F  F    + V +N V TSQYF+W+L LLPLV+   +M   + V L+ LW   Q
Sbjct: 312 D---LVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQ 368

Query: 368 CAWLFFAYQLEFKCRQVFMLIWCQSVMFYGSNVFILTQLIKYYR 411
             WL  AY LEF+ +  F+ IW   + F   N  IL Q+I +Y+
Sbjct: 369 AMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYK 412


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.331    0.145    0.448 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 61,624,754
Number of Sequences: 224733
Number of extensions: 2548808
Number of successful extensions: 6958
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 6928
Number of HSP's gapped (non-prelim): 5
length of query: 428
length of database: 73,234,838
effective HSP length: 92
effective length of query: 336
effective length of database: 52,559,402
effective search space: 17659959072
effective search space used: 17659959072
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.9 bits)
S2: 67 (31.1 bits)

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