BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000118-TA|BGIBMGA000118-PA|IPR000719|Protein kinase, IPR011009|Protein kinase-like, IPR008271|Serine/threonine protein kinase, active site, IPR002290|Serine/threonine protein kinase (900 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 84 7e-17 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 83 2e-16 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 81 9e-16 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 79 2e-15 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 79 2e-15 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 45 4e-05 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 45 5e-05 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 41 9e-04 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 40 0.001 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 39 0.004 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 39 0.004 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 39 0.004 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 39 0.004 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 38 0.005 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 38 0.008 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 37 0.011 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 37 0.011 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 37 0.011 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 37 0.014 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 37 0.014 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 36 0.019 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 36 0.019 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 36 0.019 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 36 0.019 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 36 0.025 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 36 0.033 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 35 0.044 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 35 0.058 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 35 0.058 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 35 0.058 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 35 0.058 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 35 0.058 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 35 0.058 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 34 0.077 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 34 0.10 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 34 0.10 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 34 0.10 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 34 0.10 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 34 0.10 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 34 0.10 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 34 0.10 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 33 0.13 SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizos... 33 0.18 SPAC13C5.02 |dre4||DNA replication protein Dre4|Schizosaccharomy... 33 0.18 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 33 0.18 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 33 0.23 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 33 0.23 SPBC23G7.07c |||replication regulator |Schizosaccharomyces pombe... 33 0.23 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 32 0.31 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 32 0.31 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 32 0.41 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 32 0.41 SPCC1393.02c |||non-specific DNA binding protein Spt2 |Schizosac... 32 0.41 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 31 0.54 SPAC29E6.10c ||SPAC30.14c|kinetochore protein |Schizosaccharomyc... 31 0.71 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 31 0.71 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 31 0.71 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 31 0.71 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 31 0.94 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 31 0.94 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 31 0.94 SPCC1919.15 |brl1|SPCC790.01, rfp2|ubiquitin-protein ligase E3 B... 30 1.2 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 30 1.2 SPAC140.02 |gar2||GAR family|Schizosaccharomyces pombe|chr 1|||M... 30 1.2 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 30 1.2 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 30 1.2 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 30 1.2 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 30 1.2 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 30 1.6 SPBC947.07 |||ribosome biogenesis protein Rrp14-C|Schizosaccharo... 30 1.6 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 30 1.6 SPAC17C9.03 |tif471||translation initiation factor eIF4G |Schizo... 29 2.2 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 29 2.2 SPAC890.05 |||ribosome biogenesis protein|Schizosaccharomyces po... 29 2.2 SPBC16E9.02c |||CUE domain protein Cue5 |Schizosaccharomyces pom... 29 2.2 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 29 2.2 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 29 2.2 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 29 2.9 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 29 2.9 SPBC947.05c |||ferric-chelate reductase |Schizosaccharomyces pom... 29 2.9 SPAC1B3.13 |||U3 snoRNP-associated protein Nan1|Schizosaccharomy... 29 2.9 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 29 3.8 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 29 3.8 SPBC13E7.03c |||RNA hairpin binding protein |Schizosaccharomyces... 29 3.8 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 28 5.0 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 28 5.0 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 28 5.0 SPAC4F8.13c |rng2||IQGAP|Schizosaccharomyces pombe|chr 1|||Manual 28 5.0 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 28 5.0 SPAC23G3.06 |||U3 snoRNP protein Nop58 |Schizosaccharomyces pomb... 27 8.8 SPBC1105.14 |rsv2||transcription factor Rsv2|Schizosaccharomyces... 27 8.8 SPAC1527.03 |||RNA-binding protein|Schizosaccharomyces pombe|chr... 27 8.8 SPAC110.04c |pss1|ssp1, SPAP14E8.01c|heat shock protein Pss1|Sch... 27 8.8 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 27 8.8 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 27 8.8 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 84.2 bits (199), Expect = 7e-17 Identities = 50/147 (34%), Positives = 79/147 (53%), Gaps = 7/147 (4%) Query: 371 SQSNGLIYLLDFGLASKFLDSDGKHKDFGMDARKAHDGTLEYSSRDSHIGAH-SRRSDLE 429 S++ +IY +DFG+A ++ D H + K+ GT Y S ++H+G SRR DLE Sbjct: 147 SKTENVIYAVDFGMAKQYRDPK-THVHRPYNEHKSLSGTARYMSINTHLGREQSRRDDLE 205 Query: 430 TLGYNLLDWLTGTLPWKTSEVLAEPDLVHALKKNFMGDIKLLLKTCFKTEFYPQFMEKYL 489 ++G+ + +L G+LPW+ + K +G+ K + E YP+ +Y+ Sbjct: 206 SMGHVFMYFLRGSLPWQGLKAATNKQ-----KYEKIGEKKQVTPLKELCEGYPKEFLQYM 260 Query: 490 EYVTSLDFPEKPDYDYCRSLFRSELLK 516 Y +L + E PDYDY RSLF S LL+ Sbjct: 261 IYARNLGYEEAPDYDYLRSLFDSLLLR 287 Score = 33.9 bits (74), Expect = 0.10 Identities = 34/158 (21%), Positives = 70/158 (44%), Gaps = 25/158 (15%) Query: 53 WRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQAAK 112 +R+GK IG GSFG ++ + ++N+ P+ ++ R ++ + Sbjct: 15 YRVGKKIGEGSFGMLFQGVNLINNQ------------------PIALKFES--RKSEVPQ 54 Query: 113 VKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRT-RVLDLKN 171 ++ L K +G+P + + E Y LV+ L + R K Sbjct: 55 LRDEYLTYKLL-MGLPGIPSVYYYGQEGM---YNLLVMDLLGPSLEDLFDYCGRRFSPKT 110 Query: 172 VLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGTR 209 V ++A Q++ ++ +H + + + DIK N ++GF G++ Sbjct: 111 VAMIAKQMITRIQSVHERHFIYRDIKPDNFLIGFPGSK 148 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 82.6 bits (195), Expect = 2e-16 Identities = 50/149 (33%), Positives = 79/149 (53%), Gaps = 7/149 (4%) Query: 371 SQSNGLIYLLDFGLASKFLDSDGKHKDFGMDARKAHDGTLEYSSRDSHIGAH-SRRSDLE 429 S++ ++Y++DFG+A + D K + RK+ GT Y S ++H+G SRR DLE Sbjct: 144 SRNANMVYMVDFGMAKYYRDPKTK-QHIPYSERKSLSGTARYMSINTHLGREQSRRDDLE 202 Query: 430 TLGYNLLDWLTGTLPWKTSEVLAEPDLVHALKKNFMGDIKLLLKTCFKTEFYPQFMEKYL 489 +LG+ + +L G+LPW+ L + H +K + + K +P KY+ Sbjct: 203 SLGHVFMYFLRGSLPWQG---LKAANNKHKYEK--ISEKKQSTSISELCAGFPNEFSKYM 257 Query: 490 EYVTSLDFPEKPDYDYCRSLFRSELLKNG 518 YV SL+F E+PDY + + LF L NG Sbjct: 258 TYVRSLEFDEEPDYAFLQELFDDVLRANG 286 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 80.6 bits (190), Expect = 9e-16 Identities = 50/152 (32%), Positives = 79/152 (51%), Gaps = 9/152 (5%) Query: 369 VLSQSNGLIYLLDFGLASKFLDSDGKHKDFGMDARKAHDGTLEYSSRDSHIGAH-SRRSD 427 ++ + + ++ ++DFGLA K+ D H K GT Y+S ++HIG SRR D Sbjct: 138 LMKKHSNVVTMIDFGLAKKYRDFK-THVHIPYRDNKNLTGTARYASINTHIGIEQSRRDD 196 Query: 428 LETLGYNLLDWLTGTLPWKTSEVLAEPDLVHALKKNFMGD-IKLLLKTCFKTEFYPQFME 486 LE+LGY LL + G+LPW+ + + ++ +G +++L K P+ Sbjct: 197 LESLGYVLLYFCRGSLPWQGLQADTKEQKYQRIRDTKIGTPLEVLCKGL------PEEFI 250 Query: 487 KYLEYVTSLDFPEKPDYDYCRSLFRSELLKNG 518 Y+ Y L F EKP+Y Y R LFR L++ G Sbjct: 251 TYMCYTRQLSFTEKPNYAYLRKLFRDLLIRKG 282 Score = 49.6 bits (113), Expect = 2e-06 Identities = 50/158 (31%), Positives = 77/158 (48%), Gaps = 24/158 (15%) Query: 47 DIQL-KKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLI 105 DI++ K+RIG+ IG GSFG+IYL + V+ E + VK+EP L H L Sbjct: 5 DIKIGNKYRIGRKIGSGSFGQIYLGLNTVNGE------QVAVKLEP-----LKARHHQL- 52 Query: 106 RTAQAAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRTR 165 + + + + K +G+P G N+ V L+ P + DL R Sbjct: 53 ----EYEFRVYNILKGN--IGIPTIRWFGVTNSYNAMVMD--LLGPSLE-DLFCYCGRK- 102 Query: 166 VLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 LK VL+LA Q++ +EY+H + + H DIK N ++ Sbjct: 103 -FTLKTVLLLADQLISRIEYVHSKSFLHRDIKPDNFLM 139 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 79.4 bits (187), Expect = 2e-15 Identities = 48/136 (35%), Positives = 68/136 (50%), Gaps = 7/136 (5%) Query: 377 IYLLDFGLASKFLDSDGKHKDFGMDARKAHDGTLEYSSRDSHIGAH-SRRSDLETLGYNL 435 + ++DFGLA K+ D H K GT Y+S ++H+G SRR DLE+LGY L Sbjct: 147 VNIIDFGLAKKYRDHK-THLHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVL 205 Query: 436 LDWLTGTLPWKTSEVLAEPDLVHALKKNFMGDIKLLLKTCFKTEFYPQFMEKYLEYVTSL 495 + + G+LPW+ + + + + K+ T +PQ YL Y SL Sbjct: 206 VYFCRGSLPWQGLKATTKKQKYEKIMEK-----KISTPTEVLCRGFPQEFSIYLNYTRSL 260 Query: 496 DFPEKPDYDYCRSLFR 511 F +KPDY Y R LFR Sbjct: 261 RFDDKPDYAYLRKLFR 276 Score = 46.8 bits (106), Expect = 1e-05 Identities = 47/165 (28%), Positives = 75/165 (45%), Gaps = 24/165 (14%) Query: 52 KWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQAA 111 K+RIG+ IG GSFG IYL ++ V E +K+E +E + + Sbjct: 10 KYRIGRKIGSGSFGDIYLGTNVVSGE------EVAIKLESTRAKHPQLEYEYRVYRILSG 63 Query: 112 KVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRTRVLDLKN 171 V G+P G D N+ V L+ P + DL +R LK Sbjct: 64 GV------------GIPFVRWFGVECDYNAMVMD--LLGPSLE-DLFNFCNRK--FSLKT 106 Query: 172 VLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGTRIGKIPVL 216 VL+LA Q++ +E++H + + H DIK N ++G G R ++ ++ Sbjct: 107 VLLLADQLISRIEFIHSKSFLHRDIKPDNFLMGI-GKRGNQVNII 150 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 79.4 bits (187), Expect = 2e-15 Identities = 62/227 (27%), Positives = 101/227 (44%), Gaps = 13/227 (5%) Query: 371 SQSNGLIYLLDFGLASKFLDSDGKHKDFGMDARKAHDGTLEYSSRDSHIGAH-SRRSDLE 429 S++ +IY++DFG+ + D K + +K GT Y S ++H+G SRR DLE Sbjct: 144 SKNANMIYVVDFGMVKFYRDPVTK-QHIPYREKKNLSGTARYMSINTHLGREQSRRDDLE 202 Query: 430 TLGYNLLDWLTGTLPWKTSEVLAEPDLVHALKKNFMGDIKLLLKTCFKTEFYPQFMEKYL 489 LG+ + +L G+LPW+ + + + L F EFY KY+ Sbjct: 203 ALGHVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQSTPLRELCAGFPEEFY-----KYM 257 Query: 490 EYVTSLDFPEKPDYDYCRSLFRSELLKNGCSEKESLNFIELS-----MSPMNRKLSYTKK 544 Y +L F PDYDY + LF L + +E E+ ++ L+ S +R + Sbjct: 258 HYARNLAFDATPDYDYLQGLFSKVLERLNTTEDENFDWNLLNNGKGWQSLKSRNAETENQ 317 Query: 545 FGRKNTPPNFLARNGIKKPH-ERENVWSLENDLKLELLRQTLNSSRD 590 K P +++ + H +NV S +D + LNS+ D Sbjct: 318 RSSKPPAPKLESKSPALQNHASTQNVVSKRSDYEKPFAEPHLNSASD 364 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 45.2 bits (102), Expect = 4e-05 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 21/167 (12%) Query: 42 GIVFTDIQLKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEI 101 G + + + + IGKP+G+G FGR+YLA + ++V ++ L V+ Sbjct: 78 GPQWREFHIGMFEIGKPLGKGKFGRVYLAKEK--------KTGFIVALKTLHKSEL-VQS 128 Query: 102 HCLIRTAQAAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLP-RYDVDLHKI 160 + + +++S K RL G F DE K +L+L +L++ Sbjct: 129 KIEKQVRREIEIQSNLRHKNILRL-------YGHFHDE----KRIYLILEFAGRGELYQH 177 Query: 161 ISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 + R + + Q+ + L YLH + H DIK N++LG DG Sbjct: 178 LRRAKRFSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILLGIDG 224 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 44.8 bits (101), Expect = 5e-05 Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 22/150 (14%) Query: 59 IGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQAAKVKSWRL 118 IG G++G++Y A + V ++ +++E +G I T + K+ Sbjct: 283 IGEGTYGKVYKAINTVTGDLVALKR---IRLEQEKDG-------FPITTVREVKILQRLR 332 Query: 119 EKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRTRV-LDLKNVLVLAI 177 K RL + + + E S V ++V D DL ++ +++ N+ L+ Sbjct: 333 HKNIVRL-LEIMV-------EKSSV---YMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSK 381 Query: 178 QILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 QI + L YLHH+G H DIK SN++L +G Sbjct: 382 QIFEALAYLHHRGVLHRDIKGSNILLNNNG 411 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 40.7 bits (91), Expect = 9e-04 Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 1/46 (2%) Query: 167 LDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGT-RIG 211 LD V + +++ L+++HH+ Y H D+K +N+M+ F+GT +IG Sbjct: 665 LDEFRVWKILVEVALGLQFIHHKNYVHLDLKPANVMITFEGTLKIG 710 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 40.3 bits (90), Expect = 0.001 Identities = 20/63 (31%), Positives = 30/63 (47%) Query: 144 KYRFLVLPRYDVDLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 KY L L D DLH ++ + LD + QI+ ++Y H H D+K N++L Sbjct: 94 KYTVLALEYMDTDLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHLHRVAHRDLKLENILL 153 Query: 204 GFD 206 D Sbjct: 154 NKD 156 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 38.7 bits (86), Expect = 0.004 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGTRIGKI 213 +L + I + R LD V A +IL +EY+H G H D+K N++ FDG KI Sbjct: 139 ELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSCGIIHRDLKPENIL--FDGNMHVKI 194 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 38.7 bits (86), Expect = 0.004 Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 21/163 (12%) Query: 43 IVFTDIQLKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIH 102 ++F D L K ++G GSFG +YLA N + + V ++ N H Sbjct: 15 VIFEDRYLVKQKLGD----GSFGTVYLAQRKEKNGLYE-----TVAVKKLKNSSKPKPKH 65 Query: 103 CLIRTAQAAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIIS 162 L++ ++ ++ ++ K + + +F D + FLV+ D +L ++ Sbjct: 66 ELLKLRESLALR--KISKHPCLIDL-----LETFMDPYRNI---FLVMEFMDCNLFQLFK 115 Query: 163 RT--RVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 R R+ + + +QI+ +E++H G+ H DIK N+++ Sbjct: 116 RRQGRLFTKETAFNILLQIISGIEHIHKHGFMHRDIKPENILV 158 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 38.7 bits (86), Expect = 0.004 Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 20/159 (12%) Query: 50 LKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQ 109 + ++I KPI +G+FG +YLA + + +KI +N +I Q Sbjct: 586 INDYKILKPISKGAFGSVYLAQKRTTGDY------FAIKILKKSN---------MIAKNQ 630 Query: 110 AAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDV-DLHKIISRTRVLD 168 V++ R + G ++A +T ++ Y +LV+ + D ++ VLD Sbjct: 631 VINVRAERAILMSQ--GESPFVAKLYYTFQSKD--YLYLVMEYLNGGDCGSLLKTMGVLD 686 Query: 169 LKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 L + + + L LH +G H DIK NL++ +G Sbjct: 687 LDWIRTYIAETVLCLGDLHDRGIIHRDIKPENLLISQNG 725 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 38.7 bits (86), Expect = 0.004 Identities = 17/37 (45%), Positives = 23/37 (62%) Query: 172 VLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGT 208 V + Q+L L YLH+QG H DIK +N++ DGT Sbjct: 108 VALYTFQVLQGLLYLHNQGVIHRDIKGANILTTKDGT 144 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 38.3 bits (85), Expect = 0.005 Identities = 15/30 (50%), Positives = 21/30 (70%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 Q+L L YLH +G H D+K+ NL++ FDG Sbjct: 938 QVLYGLSYLHSKGIIHRDLKADNLLIDFDG 967 Score = 32.3 bits (70), Expect = 0.31 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 8/80 (10%) Query: 379 LLDFGLASKFLDSD-GKHKD--FGMDARKAHDGTLEYSS----RDSHIGAHSRRSDLETL 431 L+DF K D KH D + DA + G++ + + + H G +S + D+ +L Sbjct: 962 LIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQG-YSAKVDVWSL 1020 Query: 432 GYNLLDWLTGTLPWKTSEVL 451 G +L+ L G PW T E + Sbjct: 1021 GCVVLEMLAGRRPWSTDEAI 1040 Score = 29.5 bits (63), Expect = 2.2 Identities = 12/35 (34%), Positives = 20/35 (57%) Query: 36 DEALPPGIVFTDIQLKKWRIGKPIGRGSFGRIYLA 70 D + G V + KW G+ IG G++G+++LA Sbjct: 808 DTTITSGSVVSQNATFKWMKGELIGNGTYGKVFLA 842 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 37.5 bits (83), Expect = 0.008 Identities = 39/154 (25%), Positives = 65/154 (42%), Gaps = 10/154 (6%) Query: 50 LKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQ 109 + + I K +GRG G++ L D V E+ +KI P T ++ ++Q Sbjct: 132 INHYEIIKELGRGMHGKVKLGRDTVTRELL------AIKIIPKTERR--PKLGRANASSQ 183 Query: 110 AAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRTRVLDL 169 KV+ R K+ P + D+ S K ++ ++ + VL + Sbjct: 184 KEKVR--REIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSI 241 Query: 170 KNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 ++ LEYLH+QG H DIK +NL+L Sbjct: 242 SEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLL 275 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 37.1 bits (82), Expect = 0.011 Identities = 16/48 (33%), Positives = 27/48 (56%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 +L+ ++R + LD K + Q+ ++YLH QG H D+K N+ L Sbjct: 109 ELYDWVAREKRLDEKTTCRIMWQLCCAIQYLHRQGCVHRDLKLENIFL 156 Score = 28.3 bits (60), Expect = 5.0 Identities = 11/24 (45%), Positives = 17/24 (70%) Query: 53 WRIGKPIGRGSFGRIYLASDDVDN 76 +RI +G GSFG++YLA+ + N Sbjct: 31 YRIESVVGEGSFGKVYLAAHLLTN 54 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 37.1 bits (82), Expect = 0.011 Identities = 17/51 (33%), Positives = 29/51 (56%) Query: 157 LHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 L +++ R+ D + V +Q+L+ L Y+H Q H DIK +N++L G Sbjct: 1123 LADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRG 1173 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 37.1 bits (82), Expect = 0.011 Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 1/57 (1%) Query: 147 FLVLPRYDVDLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 + V DLH++++ +R L+ + + QIL L+++H G H D+K SN+++ Sbjct: 94 YFVTELLGTDLHRLLT-SRPLETQFIQYFLYQILRGLKFVHSAGVIHRDLKPSNILI 149 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 36.7 bits (81), Expect = 0.014 Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 147 FLVLPRYDVDLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 ++V + DL+++I R++ L + QIL L+ +H G H D+K SNL+L Sbjct: 116 YIVQELMETDLYRVI-RSQPLSDDHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLL 171 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 36.7 bits (81), Expect = 0.014 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 DL K I +VL L++ QIL + YL Q H D+K N+++G DG Sbjct: 218 DLFKQIEE-KVLTLEDKCCYLKQILQAVAYLQSQRIAHRDLKPENILIGRDG 268 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 36.3 bits (80), Expect = 0.019 Identities = 51/201 (25%), Positives = 82/201 (40%), Gaps = 22/201 (10%) Query: 46 TDIQLKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLI 105 TD Q KW G IG GSFG++YL + E+ + + + H + Sbjct: 387 TDDQSIKWIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDR------HAKL 440 Query: 106 RTAQAAKVKSWRLEKKQKRLGMPVYIASGSFTDE-NSGVKYRFLVLPRYDV-DLHKIISR 163 A A ++ L ++ + Y+ S +D N ++Y +P V L + Sbjct: 441 LDALAGEIA---LLQELSHEHIVQYLGSNLNSDHLNIFLEY----VPGGSVAGLLTMYGS 493 Query: 164 TRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGTRIGKIPVLKSTPSYQ 223 +KN + Q L LEYLH +G H DIK +N+++ GKI + S + Sbjct: 494 FEETLVKNFIK---QTLKGLEYLHSRGIVHRDIKGANILV----DNKGKIKISDFGISKK 546 Query: 224 KETKEVAVLSGKHRRAKPGKS 244 E + +G R + G S Sbjct: 547 LELNSTSTKTGGARPSFQGSS 567 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 36.3 bits (80), Expect = 0.019 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 147 FLVLPRYDVDLHKIISRTRVLDLKN-VLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGF 205 +LV+ + DL ++ L++ V L +Q+L ++HH Y H D+K SNL++ Sbjct: 149 YLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNN 208 Query: 206 DG 207 G Sbjct: 209 TG 210 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 36.3 bits (80), Expect = 0.019 Identities = 18/51 (35%), Positives = 28/51 (54%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFD 206 DL + +D ++ L Q+L+ L +LH QG TH DIK N+++ D Sbjct: 255 DLMDFLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITND 305 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 36.3 bits (80), Expect = 0.019 Identities = 15/30 (50%), Positives = 21/30 (70%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 Q+L+ L YLH QG H DIK++N++ DG Sbjct: 110 QVLEALVYLHGQGKMHRDIKAANILTMKDG 139 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 35.9 bits (79), Expect = 0.025 Identities = 17/58 (29%), Positives = 28/58 (48%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGTRIGKI 213 DL +++ + L + QIL L+YLH Q H D+K N+++ I +I Sbjct: 242 DLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQNIIHRDLKLENILIASSSDTIFRI 299 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 35.5 bits (78), Expect = 0.033 Identities = 15/51 (29%), Positives = 28/51 (54%) Query: 157 LHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 L + + R+ D + V +Q+L+ L Y+H G +H D+K N++ +G Sbjct: 1206 LFEFLRYGRIEDELVIQVYVLQLLEGLAYIHSCGVSHQDVKPENILFDHNG 1256 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 35.1 bits (77), Expect = 0.044 Identities = 14/46 (30%), Positives = 29/46 (63%) Query: 169 LKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGTRIGKIP 214 LK++ +L+ Q+ + +LH G H+D+K N++L + +R ++P Sbjct: 462 LKHIQMLSQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLP 507 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 34.7 bits (76), Expect = 0.058 Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 172 VLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 + + + L+ L++LH G H DIKS N++L G Sbjct: 482 IAAICKETLEGLQHLHENGIVHRDIKSDNILLSLQG 517 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 34.7 bits (76), Expect = 0.058 Identities = 38/155 (24%), Positives = 56/155 (36%), Gaps = 5/155 (3%) Query: 55 IGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQAAKVK 114 +GK IG GS G++ +A E +F + V ++ P + AQ+ K K Sbjct: 127 LGKTIGAGSMGKVKVAHHLKTGE--QFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNK 184 Query: 115 SWRL--EKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRTRVLDLKNV 172 R E L YI + Y L IIS ++ + K Sbjct: 185 EIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKE-KQA 243 Query: 173 LVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 QI L YLH H D+K N+++ G Sbjct: 244 RKFVRQIGSALSYLHQNSVVHRDLKIENILISKTG 278 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 34.7 bits (76), Expect = 0.058 Identities = 16/47 (34%), Positives = 27/47 (57%) Query: 157 LHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 L +++ + + L V L +QIL L+Y+H + H D+K N+ML Sbjct: 125 LMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHRDLKLGNIML 171 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 34.7 bits (76), Expect = 0.058 Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 1/53 (1%) Query: 151 PRYDVDLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 PR D+ L I R L K+ + QIL L Y+H QG H DIK N+++ Sbjct: 541 PRGDL-LSLIEDRHDRLGKKDFECMIKQILRGLNYIHSQGIAHRDIKPENILI 592 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 34.7 bits (76), Expect = 0.058 Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 20/163 (12%) Query: 46 TDIQLKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLI 105 T L ++ + K I RG++GR+YLA + + +K+ P ++ Sbjct: 521 TPHSLDEFILLKEINRGAYGRVYLAKKRSSGKY------FALKMIPKSS----------- 563 Query: 106 RTAQAAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDV-DLHKIISRT 164 K+K LEK+ + + +SG Y LV+ ++ D +I + Sbjct: 564 -LDSLKKIKGLLLEKRNMHIQRYGPNTVKLYYAFDSG-DYLCLVMDYFNGGDCETLIQKL 621 Query: 165 RVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 L + V A ++L+ +E LH G H DIK +N+++ G Sbjct: 622 GPLPEQWVCQYAAELLNAIELLHQDGIIHHDIKPANMLVDETG 664 Score = 32.3 bits (70), Expect = 0.31 Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 3/75 (4%) Query: 403 RKAHDGTLEYSSRDSHIGAHSRRSDLETLGYNLLDWLTGTLPWKTSEVLAEPDLVHALKK 462 +K GT Y + + +G ++ D+ +G + + LTGT P++ + V A + +++ Sbjct: 774 KKDISGTPNYMAPEILMGVDTQMGDIWAMGCVIFEMLTGTRPFEANTVKA---IWARIER 830 Query: 463 NFMGDIKLLLKTCFK 477 N +G K + ++C K Sbjct: 831 NDIGWTKRVKESCSK 845 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 34.7 bits (76), Expect = 0.058 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 2/73 (2%) Query: 139 ENSGVKYRFLVLPRYD--VDLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDI 196 E G +R VL Y L ++ LD++ V + IL+ L LH G +H + Sbjct: 316 ETRGYGWRLYVLQEYSPKFTLFSLLQTVLTLDVETVRAFSNNILEGLAELHRLGISHKSL 375 Query: 197 KSSNLMLGFDGTR 209 N++L G R Sbjct: 376 HLDNVVLFHSGHR 388 Score = 33.9 bits (74), Expect = 0.10 Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLMLGFD-GTRIGKIPVLKSTPSYQ 223 QIL+ L Y+H +G H D+K N+ L + ++G + +YQ Sbjct: 755 QILEALAYIHSRGMMHRDLKPGNIFLDENRNVKLGDFGLATENENYQ 801 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 34.3 bits (75), Expect = 0.077 Identities = 11/30 (36%), Positives = 20/30 (66%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 + L L+++HH G H DIK++N+++ G Sbjct: 116 ETLQALKFIHHAGIIHRDIKAANILVSMSG 145 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 33.9 bits (74), Expect = 0.10 Identities = 15/52 (28%), Positives = 26/52 (50%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 D ++S + VL + A ++ ++ LH GY H D+K N ++G G Sbjct: 292 DFRTLLSNSGVLRDHHAKFYATEMFLAIDALHQLGYIHRDLKPENFLVGASG 343 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 33.9 bits (74), Expect = 0.10 Identities = 34/159 (21%), Positives = 67/159 (42%), Gaps = 20/159 (12%) Query: 50 LKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQ 109 ++ + I KPI +G+FG +YL+ + E+ Y +K+ + +I Q Sbjct: 561 IQDYEIIKPISKGTFGTVYLSRKNTTGEI------YAIKVLRKVD---------MISKNQ 605 Query: 110 AAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDV-DLHKIISRTRVLD 168 A VK+ R + ++A + ++ Y +LV+ + D ++ + Sbjct: 606 VANVKAERAVLMAQEES--AFVAKLYYAFQSRD--YLYLVMEFMNGGDCASLLKSLYTIP 661 Query: 169 LKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 + ++ LE+LH G H DIK N+++ G Sbjct: 662 ESWAKIYIAEVALGLEHLHRLGIIHRDIKPDNILMSITG 700 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 33.9 bits (74), Expect = 0.10 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGTRIGKIPV 215 D+ R + + ++ + A Q+ L YLH G H DIK NL++ + T I K+ Sbjct: 111 DMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYK-TGILKLCD 169 Query: 216 LKSTPSYQKETKEVAVLSGKHRRA 239 S V+ + ++ RA Sbjct: 170 FGSAKVLVPSEPNVSYICSRYYRA 193 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 33.9 bits (74), Expect = 0.10 Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 21/153 (13%) Query: 53 WRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQAAK 112 + + + +G G+FG +YLA+ ++ K+ ++ E+H L+R ++ Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENEN 95 Query: 113 VKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRTR--VLDLK 170 + + +YI D+ + +V+ D +L+++IS + L L+ Sbjct: 96 IVNI----------FDLYI------DQ---FRCLHIVMEFLDCNLYQLISTRKNDPLTLE 136 Query: 171 NVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 V + QI L ++H G+ H D+K N+++ Sbjct: 137 QVQDIMRQIFKGLNHIHTNGFFHRDMKPENILI 169 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 33.9 bits (74), Expect = 0.10 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 22/119 (18%) Query: 369 VLSQSNGLIYLLDFGLASKFLDSDGKHKDFGMDARKAHDGTLEYSSRDS-HIGAHSRRSD 427 V+ S G I L DFG++ + ++S + GT Y S + G ++ +SD Sbjct: 192 VVVNSRGEIKLCDFGVSGELVNS----------VAQTFVGTSTYMSPERIRGGKYTVKSD 241 Query: 428 LETLGYNLLDWLTGTLPWKTSEV---LAEPDLVHA--------LKKNFMGDIKLLLKTC 475 + +LG ++++ T LPW S + + DL+H L +F D++L + C Sbjct: 242 IWSLGISIIELATQELPWSFSNIDDSIGILDLLHCIVQEEPPRLPSSFPEDLRLFVDAC 300 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 33.9 bits (74), Expect = 0.10 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 176 AIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG----TRIGKIPVLKSTPSYQKETKEVAV 231 A I+D ++Y+H +G H D+K N++L + T G +L S+ +E A Sbjct: 204 AALIVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHAD 263 Query: 232 LSGKHRRAKPGKSR 245 H R+ G +R Sbjct: 264 KPQAHSRSFVGTAR 277 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 33.9 bits (74), Expect = 0.10 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 137 TDENSGVKYRFLVL---PRYDVDLHKIISRTRV-LDLKNVLVLAIQILDVLEYLHHQGYT 192 T +NS Y LVL P ++ +R ++ + + V + Q+L L Y+H G Sbjct: 95 TGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHASGIC 154 Query: 193 HSDIKSSNLML 203 H DIK NL+L Sbjct: 155 HRDIKPQNLLL 165 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 33.5 bits (73), Expect = 0.13 Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Query: 165 RVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGT-RIGKIPVLKSTP 220 +V+D V + Q+ L ++H + H D+K SN+++ DG ++G + S P Sbjct: 387 QVMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLP 443 >SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizosaccharomyces pombe|chr 2|||Manual Length = 1706 Score = 33.1 bits (72), Expect = 0.18 Identities = 18/57 (31%), Positives = 28/57 (49%) Query: 147 FLVLPRYDVDLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 +LV P +L+ IS L+L + Q+L + H G H DIKS N+++ Sbjct: 98 YLVRPYVTHNLYDRISTRPFLELTEKKWIMFQLLKGISDCHRLGVCHGDIKSENILI 154 >SPAC13C5.02 |dre4||DNA replication protein Dre4|Schizosaccharomyces pombe|chr 1|||Manual Length = 411 Score = 33.1 bits (72), Expect = 0.18 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Query: 461 KKNFMGDIKLLLKTCFKTEFYPQFMEKYLEYVTSLDFPEKPDYDYCRSLFRS-ELLKNGC 519 +KN + D LL + T +PQF KY + T L P + D+ LFR ++L+ Sbjct: 303 RKNTLSDFWTLLHSLPSTLLWPQFKRKYRKSST-LQIPGYSERDF-EKLFREFQILRKQP 360 Query: 520 SEKESLNFIELSMS 533 + + LNF +L S Sbjct: 361 MQDKLLNFKKLCKS 374 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 33.1 bits (72), Expect = 0.18 Identities = 14/42 (33%), Positives = 23/42 (54%) Query: 166 VLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 +L K+ A ++ LEYLH G+ + D+K N++L G Sbjct: 251 ILPEKDACFYAAEVTAALEYLHLMGFIYRDLKPENILLHQSG 292 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 32.7 bits (71), Expect = 0.23 Identities = 16/53 (30%), Positives = 28/53 (52%), Gaps = 2/53 (3%) Query: 156 DLHKIISRTRVLDLKNVLVLAI--QILDVLEYLHHQGYTHSDIKSSNLMLGFD 206 DL I+ +V + L+ + Q++ +E+ H G H D+K N+M+G D Sbjct: 102 DLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHSVGIYHRDLKPENIMVGND 154 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 32.7 bits (71), Expect = 0.23 Identities = 16/53 (30%), Positives = 26/53 (49%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGT 208 DL+ +I L+ Q++ ++YLH G H D+K NL+L G+ Sbjct: 442 DLYTLIMAAGRLEPMEADCFFKQLMRGVDYLHDMGVAHRDLKPENLLLTVSGS 494 >SPBC23G7.07c |||replication regulator |Schizosaccharomyces pombe|chr 2|||Manual Length = 277 Score = 32.7 bits (71), Expect = 0.23 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 6/59 (10%) Query: 184 EYLHH-QGYTHSDIKSSN---LMLGFDGTRIGKIPVLKSTPSYQKETKEVAVLSGKHRR 238 EY+ H G+T +++SN L+L R I VLK T S Q + +VA L GKH R Sbjct: 135 EYIQHLPGFTKKVVQNSNPEILVLCISALRA--IDVLKPTKSLQNKNFKVAKLFGKHIR 191 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 32.3 bits (70), Expect = 0.31 Identities = 9/30 (30%), Positives = 21/30 (70%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 Q+++ + ++H +G H D+K N++L ++G Sbjct: 120 QLMEGISFMHSKGVAHRDLKPENILLDYNG 149 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 32.3 bits (70), Expect = 0.31 Identities = 13/26 (50%), Positives = 17/26 (65%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLML 203 Q+LD + Y+H G H DIK N+ML Sbjct: 347 QLLDGVAYMHSLGIAHRDIKLDNIML 372 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 31.9 bits (69), Expect = 0.41 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 162 SRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG-TRIGKI 213 SRTR + + + QI++ + YLH H D+K +N+M+ G +IG + Sbjct: 107 SRTRQIPPSILKSILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDL 159 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 31.9 bits (69), Expect = 0.41 Identities = 17/53 (32%), Positives = 26/53 (49%) Query: 154 DVDLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFD 206 + DL+ II + L + QIL L+Y+H H D+K NL++ D Sbjct: 108 EADLNAIIKSGQPLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNAD 160 >SPCC1393.02c |||non-specific DNA binding protein Spt2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 406 Score = 31.9 bits (69), Expect = 0.41 Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 5/125 (4%) Query: 762 AMVKIYRMKE---RREAKEKIEVLKQQNGFKRETEIEPRCTRSTRSKQKPELVLTTRCTR 818 A V+I ++++ R +A+E E +Q +RE E+ + R +Q E TR Sbjct: 21 AAVQIEQLRKAQIREKAREITEERNRQRKLQRERELRQKYEEEQRRQQAMEAKRIAASTR 80 Query: 819 QKASSTDEKEVVLECKSNEQSKLKKRVAGKKIKKEVKITEGVKPANKSSKCTYRNLAVSK 878 Q +S E K + K K R+ KK +++ K + ++S N S Sbjct: 81 Q--TSERPPLSAEEAKRIREVKEKDRLESKKNERQGKPRSYNELLRQASSAPAVNETSSS 138 Query: 879 GLLDT 883 GLL + Sbjct: 139 GLLQS 143 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 31.5 bits (68), Expect = 0.54 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 157 LHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDGTRI 210 L I++R + LD A+Q+++ L YLH H D+K N++L D ++ Sbjct: 138 LEYILARGK-LDEDLARSFAMQLINALVYLHKNFIVHRDLKIENVLLTQDSRQV 190 >SPAC29E6.10c ||SPAC30.14c|kinetochore protein |Schizosaccharomyces pombe|chr 1|||Manual Length = 1085 Score = 31.1 bits (67), Expect = 0.71 Identities = 23/101 (22%), Positives = 50/101 (49%), Gaps = 5/101 (4%) Query: 763 MVKIYRMKERREAKEKI-EVLKQQNGFKRETEIEPRCTRSTRSKQKPELVLTTRCTRQKA 821 +++ YR K ++ + K+ E ++++N K+E E++ + + +K +L L RQ+ Sbjct: 556 VLQAYREKVAQQRQAKLLEEIEEENKRKQERELKKIREKEKKRDKKKQLKLAKEEERQRR 615 Query: 822 S----STDEKEVVLECKSNEQSKLKKRVAGKKIKKEVKITE 858 + + LE K E+++ K+ K ++E K E Sbjct: 616 EAERLAEQAAQKALEAKRQEEARKKREEQRLKREQEKKQQE 656 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 31.1 bits (67), Expect = 0.71 Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 DL IS+ R + + + ++++ L Y+H +G H D+K N++L G Sbjct: 113 DLRYHISQ-RKFNESVIRIWMVELVSALIYIHSKGVLHRDVKPDNILLDEKG 163 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 31.1 bits (67), Expect = 0.71 Identities = 14/33 (42%), Positives = 19/33 (57%) Query: 175 LAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 +A +L L YLH + H DIK SN++L G Sbjct: 186 IAFGVLSGLSYLHDRKIIHRDIKPSNILLTSKG 218 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 31.1 bits (67), Expect = 0.71 Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Query: 160 IISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 I++R R+ D + A Q++ + YLH +G H D+K N++L Sbjct: 589 ILARRRLEDSVACRLFA-QLISGVAYLHSRGVVHRDLKLENILL 631 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 30.7 bits (66), Expect = 0.94 Identities = 12/32 (37%), Positives = 21/32 (65%) Query: 172 VLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 + ++ ++L L YLH Q H DIK++N++L Sbjct: 106 ISIILREVLYGLNYLHGQNKIHRDIKAANILL 137 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 30.7 bits (66), Expect = 0.94 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 5/44 (11%) Query: 169 LKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGF--DGTRI 210 +KN+ +QI+D + +LH G H D+K N +L DG+ + Sbjct: 114 IKNIF---LQIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSEL 154 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 30.7 bits (66), Expect = 0.94 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 5/69 (7%) Query: 135 SFTDENSGVKYRFLVLPRYDVDLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHS 194 SF D +G Y L+ L ++ + D K +VL QI LEYL G H Sbjct: 74 SFIDNEAGSVY--LITSFKSFVLSDVMDEISI-DTKCKIVL--QISSALEYLEKHGILHR 128 Query: 195 DIKSSNLML 203 DI +N++L Sbjct: 129 DIHPNNILL 137 >SPCC1919.15 |brl1|SPCC790.01, rfp2|ubiquitin-protein ligase E3 Brl1|Schizosaccharomyces pombe|chr 3|||Manual Length = 692 Score = 30.3 bits (65), Expect = 1.2 Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 7/125 (5%) Query: 231 VLSGKHRRAKPGKSRNSNYYDDEDFKISYRSPNQSDEESDRKLTTVKNKLRKILSDRDSR 290 VLS + + S+ ++D F IS R+ Q D D KL VK K + I + S Sbjct: 299 VLSSNEEKIESINRDLSSLFEDIQFFISQRTKRQKD-IIDLKLACVKEKQQLIKTLESSL 357 Query: 291 TLHRHHAFNL--RQLSSYVN---YEDMNSSVCS-DQSYQKLIDDFGNKNLIRTTKEFRET 344 T R+ +L +Q Y N ++DM + + + +++ + N+ I E +T Sbjct: 358 TQIRNERDSLVAKQQMQYTNNLFFDDMMLLLSNLSNARVAILEGYSNRLCIWDRIERSKT 417 Query: 345 KKNNN 349 + NN Sbjct: 418 GEMNN 422 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 30.3 bits (65), Expect = 1.2 Identities = 11/28 (39%), Positives = 18/28 (64%) Query: 176 AIQILDVLEYLHHQGYTHSDIKSSNLML 203 A +++ L+YLHH + D+K NL+L Sbjct: 305 AAEVILALDYLHHNQIVYRDLKPENLLL 332 >SPAC140.02 |gar2||GAR family|Schizosaccharomyces pombe|chr 1|||Manual Length = 500 Score = 30.3 bits (65), Expect = 1.2 Identities = 33/156 (21%), Positives = 69/156 (44%), Gaps = 14/156 (8%) Query: 715 MQKDYLQNKNPTYAMKEVLAAFRKKALGKDKSTKEHDHTTHLDGYTPAMVKIYRMKERRE 774 ++K K A KE+ K + KS KE + + P+ + K++++ Sbjct: 23 IEKPSKSKKITKEAAKEIAKQSSKTDVSPKKSKKEAKRASSPE---PSKKSV---KKQKK 76 Query: 775 AKEKIEVLKQQNGFKRETEIEPRCTRSTRSKQKPELVLTTRCTRQKASSTDEKEVVLECK 834 +K+K E + +E E + S S + E + + +SS E+EV+++ + Sbjct: 77 SKKKEESSSESESESSSSESESSSSESESSSSESE-----SSSSESSSSESEEEVIVKTE 131 Query: 835 SNEQSKLKKRVAGKKIKKE---VKITEGVKPANKSS 867 ++S + + + ++E VKI E + ++ SS Sbjct: 132 EKKESSSESSSSSESEEEEEAVVKIEEKKESSSDSS 167 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 30.3 bits (65), Expect = 1.2 Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 147 FLVLPRYDVDLHKIISR-----TRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNL 201 +LV D+DL K + R LD + V Q+++ + + H + H D+K NL Sbjct: 81 YLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHSRRIIHRDLKPQNL 140 Query: 202 MLGFDG 207 ++ +G Sbjct: 141 LIDKEG 146 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 30.3 bits (65), Expect = 1.2 Identities = 14/58 (24%), Positives = 33/58 (56%), Gaps = 2/58 (3%) Query: 148 LVLPRYDVDLHKIISRT--RVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 +V+ + DL ++ + + ++L + + Q+L+ ++ +H Q HSD+K +N +L Sbjct: 393 MVMECGETDLANLLMKNMKKPINLNFIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLL 450 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 30.3 bits (65), Expect = 1.2 Identities = 41/182 (22%), Positives = 75/182 (41%), Gaps = 21/182 (11%) Query: 24 DETSSLDVSFCDDEALPPGIVFTDIQLKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNA 83 DE +S + F DDE +V D ++ + +G+GSFG++ +D E K A Sbjct: 671 DENTSSNFGF-DDERGDYKVVLGDHIAYRYEVVDFLGKGSFGQVLRC---IDYETGKLVA 726 Query: 84 RYVVKIEPHTNGPLFVEIHCLIRTAQAAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGV 143 +++ N F + L+ T K++ W M Y F D Sbjct: 727 LKIIR-----NKKRF-HMQALVETKILQKIREW---DPLDEYCMVQYTDHFYFRD----- 772 Query: 144 KYRFLVLPRYDVDLHKIISRTRVLDLKNVLVLAI--QILDVLEYLHHQGYTHSDIKSSNL 201 + + +L+++I L V++ +I Q++ L L+ + H D+K N+ Sbjct: 773 -HLCVATELLGKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENI 831 Query: 202 ML 203 +L Sbjct: 832 LL 833 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 30.3 bits (65), Expect = 1.2 Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 1/61 (1%) Query: 148 LVLPRYDVDLHKIIS-RTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFD 206 ++L D DL +I + V ++ + +L L ++H + H D+K +NL++ D Sbjct: 85 IILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISSD 144 Query: 207 G 207 G Sbjct: 145 G 145 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 29.9 bits (64), Expect = 1.6 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Query: 369 VLSQSNGLIYLLDFGLASKFLDSDGKHKDFGMDARKAHDGTLEYSSRDSHIGAHSRRSDL 428 VL SNG + L DFG++ + S K + G + A + + + + ++ ++D+ Sbjct: 447 VLVNSNGQVKLCDFGVSGNLVASISK-TNIGCQSYMAPE-RIRVGGPTNGVLTYTVQADV 504 Query: 429 ETLGYNLLDWLTGTLPW 445 +LG +L+ G P+ Sbjct: 505 WSLGLTILEMALGAYPY 521 >SPBC947.07 |||ribosome biogenesis protein Rrp14-C|Schizosaccharomyces pombe|chr 2|||Manual Length = 233 Score = 29.9 bits (64), Expect = 1.6 Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 8/130 (6%) Query: 739 KALGKDKS-TKEHDHTTHLDGYTPAMVKIYRMKERR--EAKEKIEVLKQQNGFKRETEIE 795 K GK + T HL+ + + K R+ E+ + VL Q G K+ + E Sbjct: 108 KVAGKKRGPTDVFGALKHLEAKKRRIESMDEEKRRKIEESDKWHRVLLQAEG-KKLKDNE 166 Query: 796 PRCTRSTRSKQKPELVLTTRCTRQKASSTDEKEVVLECKSNEQSKLKKRVAGKKIKKEVK 855 +S R K+K + + +K +EK+ +L + + LKKR KK KK K Sbjct: 167 QLLKKSIRRKEKEKKKSSDAWKERK---DNEKKAMLMRQQRREENLKKRRESKKSKKG-K 222 Query: 856 ITEGVKPANK 865 + KP+ K Sbjct: 223 APKKKKPSKK 232 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 29.9 bits (64), Expect = 1.6 Identities = 35/155 (22%), Positives = 66/155 (42%), Gaps = 19/155 (12%) Query: 51 KKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIRTAQA 110 +K+ I +G G+FG++ D + +V I+ N P F C++ + Sbjct: 128 RKYLILDTLGHGTFGQVARCQD--------LKTQQIVAIKVIKNKPAFYN-QCVMEVSIL 178 Query: 111 AKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRT--RVLD 168 + + + + + KR + +Y F +N + LV ++L+++I + R L Sbjct: 179 ELLNN-KYDPEDKRHLIRLY---DQFMHKN----HLCLVFELLSINLYELIKQNQFRGLH 230 Query: 169 LKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 L V A Q+L L H D+K N++L Sbjct: 231 LSLVRSFATQLLSCTSLLKQARIIHCDLKPENILL 265 >SPAC17C9.03 |tif471||translation initiation factor eIF4G |Schizosaccharomyces pombe|chr 1|||Manual Length = 1403 Score = 29.5 bits (63), Expect = 2.2 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 7/86 (8%) Query: 770 KERREAKEKIEVLKQQNGFKRETEIEPRCTRSTRSKQKPELVLTTRCTRQKASSTDEKEV 829 K +REA+EK + ++N KRE E + R K K E +++A ++E Sbjct: 584 KAKREAEEKAKREAEENA-KREA--EEKAKREAEEKAKRE---AEEKAKREAEEKAKREA 637 Query: 830 VLECKSNEQSKLKKRVAGKKIKKEVK 855 + K + K KR A +K K+E + Sbjct: 638 EEKAKREAEEK-AKREAEEKAKREAE 662 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 29.5 bits (63), Expect = 2.2 Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Query: 147 FLVLPRYDVDLHKIISRTRVLDLK-NVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGF 205 ++V P D DL ++ V + + Q+ +YLH Q H D+K++NL++ Sbjct: 117 YMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDN 176 Query: 206 DG 207 G Sbjct: 177 HG 178 >SPAC890.05 |||ribosome biogenesis protein|Schizosaccharomyces pombe|chr 1|||Manual Length = 284 Score = 29.5 bits (63), Expect = 2.2 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 773 REAKEKIEVLKQQNGFKRETEIEPRCTRSTRSKQKPELVLTTRCTRQKASSTDEKEVVLE 832 ++A+E + + + E + E R S++ K K + + +K +K+ Sbjct: 144 QKAEEDEDRVCEDASSSDEAKREKRKKHSSKKKSKKKTSTGSALDPKKLEKITKKKKKEH 203 Query: 833 CKSNEQSKLKKRVAG---KKIKKEVKITEGVKPANKSS 867 K +++S KKR +G K+ KK+ KI KP + SS Sbjct: 204 KKKDKESSSKKRKSGSSDKEEKKKKKIKLKDKPESTSS 241 >SPBC16E9.02c |||CUE domain protein Cue5 |Schizosaccharomyces pombe|chr 2|||Manual Length = 569 Score = 29.5 bits (63), Expect = 2.2 Identities = 20/99 (20%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Query: 773 REAKEKIEVLKQQNGFKRETEIEPRCTRSTRSKQKPELVLTTRCTRQKASSTDEKEVVLE 832 ++ +EK + ++ K ET+++ + T S + K E ++ T K T+ KE ++ Sbjct: 437 KDVEEKDTKITNEDTGKTETDVKAKETDSIEANDKDEKT-DSKETEDKVEETESKEADVK 495 Query: 833 CKSNEQSKL---KKRVAGKKIKKEVKITEGVKPANKSSK 868 K + ++ +++ K+ +V+ T+ K +K Sbjct: 496 AKETDSIEVDDKEEKTDSKETADKVEQTDSKDTNEKPAK 534 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 29.5 bits (63), Expect = 2.2 Identities = 16/48 (33%), Positives = 24/48 (50%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLML 203 D+ K R L +K V + A Q+ L+ L HSDIK N+++ Sbjct: 247 DILKKFGRNVGLSIKAVRLYAYQMFMALDLLKQCNVIHSDIKPDNMLV 294 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 29.5 bits (63), Expect = 2.2 Identities = 11/30 (36%), Positives = 18/30 (60%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 ++ LEYLH G+ + D+K N++L G Sbjct: 303 EVTAALEYLHLMGFIYRDLKPENILLHESG 332 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 29.1 bits (62), Expect = 2.9 Identities = 10/22 (45%), Positives = 14/22 (63%) Query: 186 LHHQGYTHSDIKSSNLMLGFDG 207 +H GY H DIK N+++ DG Sbjct: 207 VHRMGYIHRDIKPDNILIDRDG 228 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 29.1 bits (62), Expect = 2.9 Identities = 38/159 (23%), Positives = 62/159 (38%), Gaps = 20/159 (12%) Query: 47 DIQLKKWRIGKPIGRGSFGRIYLASDDVDNEVTKFNARYVVKIEPHTNGPLFVEIHCLIR 106 D L ++ I +G+GSFG++ D +V A V+K +G VE+ L R Sbjct: 512 DHLLYRYEIIDTVGKGSFGQVLKCIDHKRGQVV---AIKVIKNRQKFHGQTLVEVGILKR 568 Query: 107 TAQAAKVKSWRLEKKQKRLGMPVYIASGSFTDENSGVKYRFLVLPRYDVDLHKIISRTRV 166 +A + + Y++ F + +V +L +I Sbjct: 569 LCEADPADKNNVIR---------YLSHFDFRG------HLCIVTELLGSNLFDVIRENNY 613 Query: 167 LDLKNVLV--LAIQILDVLEYLHHQGYTHSDIKSSNLML 203 L ++V A+Q L L L Q H D+K NL+L Sbjct: 614 KGLPLIVVKSFALQGLQALRLLQGQNIIHCDLKPENLLL 652 >SPBC947.05c |||ferric-chelate reductase |Schizosaccharomyces pombe|chr 2|||Manual Length = 564 Score = 29.1 bits (62), Expect = 2.9 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 267 EESDRKLTTVKNKLRKILSDRDSRTLHRHHAFNLRQLSSYVNYEDMNSSVCSDQSYQKLI 326 E S+ T +N + DR ++ +++ YV Y+ + C QS+ K I Sbjct: 490 ESSEFSNQTTENSEMEFFDDRPDLDMY------IQKFFDYVGYQTAALAACGSQSFLKRI 543 Query: 327 DDFGNKNLIRTT 338 + NK++ TT Sbjct: 544 KNSVNKSISSTT 555 >SPAC1B3.13 |||U3 snoRNP-associated protein Nan1|Schizosaccharomyces pombe|chr 1|||Manual Length = 800 Score = 29.1 bits (62), Expect = 2.9 Identities = 14/46 (30%), Positives = 23/46 (50%) Query: 287 RDSRTLHRHHAFNLRQLSSYVNYEDMNSSVCSDQSYQKLIDDFGNK 332 R R +HR H FN+ Q + V+ +V D+ +I+D N+ Sbjct: 206 RSQRWIHREHLFNMPQKLTNVSLCGSACAVSDDEGKIHVINDISNE 251 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 28.7 bits (61), Expect = 3.8 Identities = 11/26 (42%), Positives = 16/26 (61%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLML 203 Q+L + YLH G H D+K NL++ Sbjct: 408 QLLSGVAYLHSMGLAHRDLKLDNLVV 433 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 28.7 bits (61), Expect = 3.8 Identities = 11/26 (42%), Positives = 15/26 (57%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLML 203 QI+ +EY H H D+K NL+L Sbjct: 139 QIICAIEYCHRHKIVHRDLKPENLLL 164 >SPBC13E7.03c |||RNA hairpin binding protein |Schizosaccharomyces pombe|chr 2|||Manual Length = 713 Score = 28.7 bits (61), Expect = 3.8 Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 3/90 (3%) Query: 206 DGTRIGKIPVLKSTPSYQKETKEVAVLSGKHRRAKPGKSRNSNYYDDEDFKISYRSPNQS 265 +G R + V+ S S QK+T V+++ GK+ P + NS D +++ + + Sbjct: 5 EGRRKTCLDVVDSPSSRQKQTIAVSLVDGKN---YPTRFLNSRTIDKLKQELNTSNLSTG 61 Query: 266 DEESDRKLTTVKNKLRKILSDRDSRTLHRH 295 + ++ L + K+LS+ + ++ H Sbjct: 62 EMSTNETLKNAQEVAGKLLSEENEDSISEH 91 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 28.3 bits (60), Expect = 5.0 Identities = 9/26 (34%), Positives = 17/26 (65%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLML 203 ++L L++ H +G H D+K N+M+ Sbjct: 143 ELLKALDFCHSRGIMHRDVKPHNVMI 168 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 28.3 bits (60), Expect = 5.0 Identities = 13/51 (25%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Query: 157 LHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 L II ++++ + + + + ++ +++LH + H DIKS N++L G Sbjct: 397 LTDIIEKSKLTEAQ-IARICLETCKGIQHLHARNIIHRDIKSDNVLLDNSG 446 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 28.3 bits (60), Expect = 5.0 Identities = 11/32 (34%), Positives = 18/32 (56%) Query: 176 AIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 A ++ L+Y H G + D+K N++L DG Sbjct: 789 AAEVCLALKYFHDNGIIYRDLKLDNILLSPDG 820 >SPAC4F8.13c |rng2||IQGAP|Schizosaccharomyces pombe|chr 1|||Manual Length = 1489 Score = 28.3 bits (60), Expect = 5.0 Identities = 28/127 (22%), Positives = 56/127 (44%), Gaps = 5/127 (3%) Query: 247 SNYYDDEDFKISYRSPNQSDEESDRKLTTVKNKLRKILSDRDSRTLHRHHAFNLRQLSSY 306 SN + E + R N D + L ++NK R+ + + NLR+ ++ Sbjct: 1283 SNIVEMEKLGFANRRNNYQDMVNSIALD-IRNKSRRRMQRQRELDAGHQSLLNLREKRAF 1341 Query: 307 VNYEDMNSSVCSDQSYQKLIDDFGNKNLIRTTKEF---RETKKNNNARLKAGSNCNEADE 363 ++ + + + +Q+ + L G K LI +K++ R+ +K+ + GS A + Sbjct: 1342 LDSQLKSYNEYIEQAMETLQSKKGKKKLIPFSKQYFHMRDLRKSGRVP-RFGSFKYPALK 1400 Query: 364 IYQEAVL 370 +Y VL Sbjct: 1401 LYDRGVL 1407 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 28.3 bits (60), Expect = 5.0 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 178 QILDVLEYLHHQGYTHSDIKSSNLMLGFDGT-RIGK 212 QIL LEY H H D+K NL L G+ +IG+ Sbjct: 116 QILCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGE 151 >SPAC23G3.06 |||U3 snoRNP protein Nop58 |Schizosaccharomyces pombe|chr 1|||Manual Length = 508 Score = 27.5 bits (58), Expect = 8.8 Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 826 EKEVVLECKSNEQSKLKKR--VAGKKIKKEVKITEGVKPANKSSK 868 E ++V+E K + SKLK+ + KK KKE K + K KS + Sbjct: 446 EMDIVIEKKKKKSSKLKEADGESSKKEKKEKKDKKHKKSKRKSEE 490 >SPBC1105.14 |rsv2||transcription factor Rsv2|Schizosaccharomyces pombe|chr 2|||Manual Length = 637 Score = 27.5 bits (58), Expect = 8.8 Identities = 27/96 (28%), Positives = 37/96 (38%), Gaps = 7/96 (7%) Query: 737 RKKALGK--DKSTKEHDHTTHLDGYTPAMVKIYRMKERREAKEKIEVLKQQNGFKRETEI 794 R ALG D + + DG +MV + R+ E +KQ R + Sbjct: 365 RSHALGAAADSLLPQENSAQIYDGKDVSMVNDNMHSDVRQDSFNKESIKQ-----RIPSL 419 Query: 795 EPRCTRSTRSKQKPELVLTTRCTRQKASSTDEKEVV 830 P TRS +K +P LVL T S + VV Sbjct: 420 SPPITRSYNAKHRPSLVLGTSVNPHSLSPSQPPVVV 455 >SPAC1527.03 |||RNA-binding protein|Schizosaccharomyces pombe|chr 1|||Manual Length = 475 Score = 27.5 bits (58), Expect = 8.8 Identities = 15/73 (20%), Positives = 32/73 (43%), Gaps = 7/73 (9%) Query: 730 KEVLAAFRKKALGKDKSTKEHDHTTHL-------DGYTPAMVKIYRMKERREAKEKIEVL 782 KEVL + GK +D H + Y P+ V ++ +++ + +K + Sbjct: 37 KEVLKNLQNSLTGKTAEENLNDEANHTSSDKSKSEDYQPSNVNVWALRKEKMIPKKHSHV 96 Query: 783 KQQNGFKRETEIE 795 KQ+ F + +++ Sbjct: 97 KQEKRFSKSLQLQ 109 >SPAC110.04c |pss1|ssp1, SPAP14E8.01c|heat shock protein Pss1|Schizosaccharomyces pombe|chr 1|||Manual Length = 720 Score = 27.5 bits (58), Expect = 8.8 Identities = 16/67 (23%), Positives = 30/67 (44%) Query: 250 YDDEDFKISYRSPNQSDEESDRKLTTVKNKLRKILSDRDSRTLHRHHAFNLRQLSSYVNY 309 Y +FK Y+ S+ ++ +L T +L+K+LS + L+ N SS++ Sbjct: 246 YFAAEFKEKYKIDVLSNPKATFRLATAVERLKKVLSANANAPLNVEMIMNDIDASSFIKR 305 Query: 310 EDMNSSV 316 D + Sbjct: 306 SDFEELI 312 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 27.5 bits (58), Expect = 8.8 Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 156 DLHKIISRTRVLDLKNVLVLAIQILDVLEYLHHQGYTHSDIKSSNLMLGFDG 207 DL I R + +K ++ L+Y H G + D+K N++L DG Sbjct: 751 DLMVHIQRQQ-FSVKRARFYGAEVCLALKYFHENGIAYRDLKLDNILLCPDG 801 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 27.5 bits (58), Expect = 8.8 Identities = 11/19 (57%), Positives = 16/19 (84%) Query: 50 LKKWRIGKPIGRGSFGRIY 68 ++K++I + IG GSFGRIY Sbjct: 1 MEKYKILECIGHGSFGRIY 19 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.316 0.133 0.380 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 4,256,507 Number of Sequences: 5004 Number of extensions: 194524 Number of successful extensions: 838 Number of sequences better than 10.0: 95 Number of HSP's better than 10.0 without gapping: 74 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 665 Number of HSP's gapped (non-prelim): 180 length of query: 900 length of database: 2,362,478 effective HSP length: 79 effective length of query: 821 effective length of database: 1,967,162 effective search space: 1615040002 effective search space used: 1615040002 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 58 (27.5 bits)
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