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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000104-TA|BGIBMGA000104-PA|IPR008968|Mu2 adaptin subunit
(AP50) of AP2, IPR001392|Clathrin adaptor complex, medium chain,
IPR011012|Longin-like
         (571 letters)

Database: celegans 
           27,539 sequences; 12,573,161 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U21309-2|AAN73882.1|  515|Caenorhabditis elegans Hypothetical pr...   400   e-111
AF003130-2|AAB54125.2|  426|Caenorhabditis elegans Adaptin, mu/m...    37   0.033
U53340-2|AAA96207.1|  142|Caenorhabditis elegans Ap-2 small chai...    34   0.31 
AF016440-4|AAB65902.1|  157|Caenorhabditis elegans Adaptin, smal...    32   0.95 
Z82069-7|CAB04907.2| 1792|Caenorhabditis elegans Hypothetical pr...    31   2.2  
AL132902-15|CAC14425.1| 1792|Caenorhabditis elegans Hypothetical...    31   2.2  
U39678-2|AAL16315.1|  133|Caenorhabditis elegans Hypothetical pr...    31   2.9  
U33058-1|AAB00542.1| 6632|Caenorhabditis elegans UNC-89 protein.       31   2.9  
AF003131-5|AAV34799.1| 5992|Caenorhabditis elegans Uncoordinated...    31   2.9  
AF003131-4|AAB54132.2| 6632|Caenorhabditis elegans Uncoordinated...    31   2.9  
AF003131-3|AAV34801.1| 7122|Caenorhabditis elegans Uncoordinated...    31   2.9  
AF003131-2|AAV34800.1| 7441|Caenorhabditis elegans Uncoordinated...    31   2.9  
AF003131-1|AAP68958.1| 8081|Caenorhabditis elegans Uncoordinated...    31   2.9  
AF099001-8|AAP13778.1|  435|Caenorhabditis elegans Dumpy : short...    30   5.1  
AF099001-7|AAP13777.1|  441|Caenorhabditis elegans Dumpy : short...    30   5.1  
U70845-4|AAB09102.1|  340|Caenorhabditis elegans Hypothetical pr...    29   6.7  
Z81547-4|CAB04458.1|  368|Caenorhabditis elegans Hypothetical pr...    29   8.9  
U00031-9|AAK18871.1|  470|Caenorhabditis elegans Hypothetical pr...    29   8.9  

>U21309-2|AAN73882.1|  515|Caenorhabditis elegans Hypothetical
           protein C13B9.3 protein.
          Length = 515

 Score =  400 bits (984), Expect = e-111
 Identities = 212/524 (40%), Positives = 319/524 (60%), Gaps = 26/524 (4%)

Query: 65  LVLIAATVCTKSGKALVSRQFV-EMTKARIEGLLAAFPKLM-----TGGRQHTFVETESV 118
           +VLIAA + +K+GK LV+RQFV +M ++R+EGL+ AFPKL+        RQHTFVET+SV
Sbjct: 1   MVLIAACILSKTGKLLVARQFVNDMMRSRLEGLVDAFPKLIGNEKEAATRQHTFVETDSV 60

Query: 119 RYVYQPLDKLYMLLITTKASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFD 178
           RYVY PLD +Y++L+TTK SNILEDLETLRLF RV+PEYC    E E+L   F+L+FAFD
Sbjct: 61  RYVYHPLDNIYLVLVTTKNSNILEDLETLRLFVRVIPEYCRSNEEKEILAHDFDLIFAFD 120

Query: 179 EIVALGYRESVNLAQVRSFVEMDSHEEKIYQAVRQTQXXXXXXXXXXXXXXLQRERLEAA 238
           E+V LGYRESVNLAQ+R+F EMDSHEE+++  +++ Q              L+R + EA 
Sbjct: 121 EVVTLGYRESVNLAQIRTFTEMDSHEERVFMQIKEAQEKAAKQAMAEKAKELKRAQKEAL 180

Query: 239 KRGQPPRXXXXXXXXXXXXXXXXXXXXXXIAEKIPTTPARDTRTV-GRSAMKLGSRGTDA 297
            RG  P                       ++E     P+     + G  A+KLG +  + 
Sbjct: 181 SRGLKP-----SYQSSTGISSSSTPNAAAVSEPAAPRPSAPKGPIGGGKALKLGGKTNNE 235

Query: 298 DSFVSRLRSEGDVTAPVASAAQHDAGKPVPA--------DHKDVHLRFEERLNLIAGRDG 349
           D F+  LR +G   APV  A+       + A          + VH+R EE++N    RDG
Sbjct: 236 DDFLDTLRQQGQSIAPVQKASLSGGVSSLAAPISTAPRVKREVVHVRTEEKINTRVSRDG 295

Query: 350 DIQTFELSGLLTLRISNEQFGRIHVHVDNKDSRPLQLQTHPNVDKEAFRSTGVIGLKQAQ 409
            +++ E+   +TL I + +F  I + ++N  +   QLQ HPN+DK+ ++S+  + +K   
Sbjct: 296 GLESGEVQATVTLSIGSPEFIPISIKMNNGSAAGTQLQVHPNLDKKEWQSSSTLKIKPNG 355

Query: 410 RPFPMHSDVGVLKWRLATTNDDKLAPLSVNCWPSEGVNGGCDVNIEYELEQDHLVLTDVN 469
           +P+P++SDVG+LKW++A + +++L P+S NCWP E  + G  VNIEY L+++ + L +V 
Sbjct: 356 KPYPVNSDVGILKWKMALSEEEQL-PISFNCWPQES-SDGVQVNIEYTLQREDITLNNVR 413

Query: 470 ITIPLPSGNTSVVVHQWEGSYT-QKGRN-LIWSIPLVSKQQKTGSLEFTVTPSIPNDFFP 527
           I +PLP+  T+  V + +G Y   K +N ++WS+ ++     +G+LEF+V     + FFP
Sbjct: 414 IIVPLPTA-TAPSVGECDGEYEYHKTKNVIVWSLAVIDSSNSSGTLEFSVPNGHCDHFFP 472

Query: 528 LSVTWTSETSLALLTAVKVTQAEDGSPVDFSQEISFHADKYEFV 571
           +SV +TSE     +T  KV +  DGSPV +S E +F+++ +E V
Sbjct: 473 VSVGFTSENLFVPITVQKVVK-NDGSPVTYSVETTFNSENFEIV 515


>AF003130-2|AAB54125.2|  426|Caenorhabditis elegans Adaptin,
           mu/medium chain (clathrinassociated complex) protein 1
           protein.
          Length = 426

 Score = 37.1 bits (82), Expect = 0.033
 Identities = 26/123 (21%), Positives = 53/123 (43%), Gaps = 1/123 (0%)

Query: 77  GKALVSRQFV-EMTKARIEGLLAAFPKLMTGGRQHTFVETESVRYVYQPLDKLYMLLITT 135
           G  ++SR +  ++  + IE  +    +    G     +  + + Y Y     +Y++ I+ 
Sbjct: 13  GNVVISRNYRGDVDMSCIEKFMPLLVEKEDEGSASPVLVHQGISYTYIKYMNVYLVTISK 72

Query: 136 KASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALGYRESVNLAQVR 195
           K +N++  L  L     V  EY   L E  V +    +   FDE++  GY ++     ++
Sbjct: 73  KNTNVILVLSALYKIVEVFCEYFKTLEEEAVRDNFVIIYELFDEMLDFGYPQTTESKILQ 132

Query: 196 SFV 198
            F+
Sbjct: 133 EFI 135


>U53340-2|AAA96207.1|  142|Caenorhabditis elegans Ap-2 small chain
           (clathrin associatedcomplex) protein 2 protein.
          Length = 142

 Score = 33.9 bits (74), Expect = 0.31
 Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 3/133 (2%)

Query: 75  KSGKALVSRQFVEMTKARIEGLLAAFPKLMT-GGRQHT-FVETESVRYVYQPLDKLYMLL 132
           ++GK  +++ ++       + L+      +T    +HT FVE  + + VY+    LY  +
Sbjct: 10  RAGKTRLAKWYMHFDDDEKQKLIEEVHACVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCI 69

Query: 133 ITTKASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALG-YRESVNL 191
                 N L  LE +  F  V+ EY   + E +++   + +    DE+   G  RE+   
Sbjct: 70  CVDITDNNLYYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQT 129

Query: 192 AQVRSFVEMDSHE 204
             ++  + + S E
Sbjct: 130 KVLKQLLMLTSLE 142


>AF016440-4|AAB65902.1|  157|Caenorhabditis elegans Adaptin, small
           chain (clathrinassociated complex) protein 1 protein.
          Length = 157

 Score = 32.3 bits (70), Expect = 0.95
 Identities = 25/116 (21%), Positives = 49/116 (42%), Gaps = 6/116 (5%)

Query: 79  ALVSRQFVEMTKARIEGLLAAFPKLMTGGRQHTFVETESVRYVYQPLDKLYMLLITTKAS 138
           A   +Q  ++ +  I  +LA  PK+        F+E + ++ VY+    LY      +  
Sbjct: 22  AYPDKQKKKICRELITQILARKPKMCA------FLEYKDLKVVYKRYASLYFCCAIEQND 75

Query: 139 NILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALGYRESVNLAQV 194
           N L  LE +  +  ++ +Y   + E +++       F  DE +  G  +  +  QV
Sbjct: 76  NELITLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLAGEIQETSKKQV 131


>Z82069-7|CAB04907.2| 1792|Caenorhabditis elegans Hypothetical
           protein W04A8.7 protein.
          Length = 1792

 Score = 31.1 bits (67), Expect = 2.2
 Identities = 14/46 (30%), Positives = 25/46 (54%)

Query: 484 HQWEGSYTQKGRNLIWSIPLVSKQQKTGSLEFTVTPSIPNDFFPLS 529
           H+ +G YT+K + ++  +    KQ++   +E T+     ND F LS
Sbjct: 447 HRKDGQYTKKSKMILGQVQQRQKQEEDEQMESTMAQFTDNDPFNLS 492


>AL132902-15|CAC14425.1| 1792|Caenorhabditis elegans Hypothetical
           protein W04A8.7 protein.
          Length = 1792

 Score = 31.1 bits (67), Expect = 2.2
 Identities = 14/46 (30%), Positives = 25/46 (54%)

Query: 484 HQWEGSYTQKGRNLIWSIPLVSKQQKTGSLEFTVTPSIPNDFFPLS 529
           H+ +G YT+K + ++  +    KQ++   +E T+     ND F LS
Sbjct: 447 HRKDGQYTKKSKMILGQVQQRQKQEEDEQMESTMAQFTDNDPFNLS 492


>U39678-2|AAL16315.1|  133|Caenorhabditis elegans Hypothetical
           protein C39D10.8a protein.
          Length = 133

 Score = 30.7 bits (66), Expect = 2.9
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 6/65 (9%)

Query: 445 GVNGGCDVNIEYELEQDHLVLTDVNITIPLPSGNTSVVVHQ-WEGSYTQKGRNLIWSIPL 503
           G+  G   N E+++E      TD  ITI       SV+ H+ WEG Y Q  R+ I  +P 
Sbjct: 67  GLGPGTTKNSEFKVEH-----TDNVITIRCKYRVQSVLAHETWEGEYIQYWRSEIGQMPK 121

Query: 504 VSKQQ 508
           + + +
Sbjct: 122 IIRDE 126


>U33058-1|AAB00542.1| 6632|Caenorhabditis elegans UNC-89 protein.
          Length = 6632

 Score = 30.7 bits (66), Expect = 2.9
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%)

Query: 351  IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399
            I T +   + TL+ISN   EQ G + V   N   +DS+   L+  PNV    F+S
Sbjct: 2121 ITTIKTEDVYTLKISNPKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175


>AF003131-5|AAV34799.1| 5992|Caenorhabditis elegans Uncoordinated
            protein 89, isoform e protein.
          Length = 5992

 Score = 30.7 bits (66), Expect = 2.9
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%)

Query: 351  IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399
            I T +   + TL+ISN   EQ G + V   N   +DS+   L+  PNV    F+S
Sbjct: 1481 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 1535


>AF003131-4|AAB54132.2| 6632|Caenorhabditis elegans Uncoordinated
            protein 89, isoform a protein.
          Length = 6632

 Score = 30.7 bits (66), Expect = 2.9
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%)

Query: 351  IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399
            I T +   + TL+ISN   EQ G + V   N   +DS+   L+  PNV    F+S
Sbjct: 2121 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175


>AF003131-3|AAV34801.1| 7122|Caenorhabditis elegans Uncoordinated
            protein 89, isoform g protein.
          Length = 7122

 Score = 30.7 bits (66), Expect = 2.9
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%)

Query: 351  IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399
            I T +   + TL+ISN   EQ G + V   N   +DS+   L+  PNV    F+S
Sbjct: 2121 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175


>AF003131-2|AAV34800.1| 7441|Caenorhabditis elegans Uncoordinated
            protein 89, isoform f protein.
          Length = 7441

 Score = 30.7 bits (66), Expect = 2.9
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%)

Query: 351  IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399
            I T +   + TL+ISN   EQ G + V   N   +DS+   L+  PNV    F+S
Sbjct: 1481 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 1535


>AF003131-1|AAP68958.1| 8081|Caenorhabditis elegans Uncoordinated
            protein 89, isoform b protein.
          Length = 8081

 Score = 30.7 bits (66), Expect = 2.9
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%)

Query: 351  IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399
            I T +   + TL+ISN   EQ G + V   N   +DS+   L+  PNV    F+S
Sbjct: 2121 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175


>AF099001-8|AAP13778.1|  435|Caenorhabditis elegans Dumpy : shorter
           than wild-typeprotein 23, isoform b protein.
          Length = 435

 Score = 29.9 bits (64), Expect = 5.1
 Identities = 16/71 (22%), Positives = 34/71 (47%)

Query: 128 LYMLLITTKASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALGYRE 187
           +++  +T +  N     E L+ F+  +  Y  +L E  V N    +    DEI+  GY +
Sbjct: 63  VWICAVTRQNVNAAMVFEFLKRFADTMQSYFGKLNEENVKNNFVLIYELLDEILDFGYPQ 122

Query: 188 SVNLAQVRSFV 198
           + +   +++F+
Sbjct: 123 NTDPGVLKTFI 133


>AF099001-7|AAP13777.1|  441|Caenorhabditis elegans Dumpy : shorter
           than wild-typeprotein 23, isoform a protein.
          Length = 441

 Score = 29.9 bits (64), Expect = 5.1
 Identities = 16/71 (22%), Positives = 34/71 (47%)

Query: 128 LYMLLITTKASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALGYRE 187
           +++  +T +  N     E L+ F+  +  Y  +L E  V N    +    DEI+  GY +
Sbjct: 63  VWICAVTRQNVNAAMVFEFLKRFADTMQSYFGKLNEENVKNNFVLIYELLDEILDFGYPQ 122

Query: 188 SVNLAQVRSFV 198
           + +   +++F+
Sbjct: 123 NTDPGVLKTFI 133


>U70845-4|AAB09102.1|  340|Caenorhabditis elegans Hypothetical
           protein F22H10.5 protein.
          Length = 340

 Score = 29.5 bits (63), Expect = 6.7
 Identities = 27/124 (21%), Positives = 58/124 (46%), Gaps = 8/124 (6%)

Query: 49  KIDKHSGPDCGLFKKQLVLIAATVCTKSGKALVSRQFVEMTKARIEGLLAAFPK--LMTG 106
           K  +H+     +  +  +L + +  +    A V+  FV+M  A++  ++   P   L   
Sbjct: 132 KCGEHTQGIDAVIAELAILKSLSALSTKNHANVTENFVKMVMAKV--VIGKHPTSLLKAW 189

Query: 107 GRQHTFVETESVRYVYQPLDKLYMLLITTKASNILE--DLETLRLFSRVVPE--YCVQLT 162
                  E+E++R      ++LY++LI +K    LE   +E++  F  ++ +  Y + + 
Sbjct: 190 DTYRVEEESENIRPSKFNKNQLYLVLILSKGGTALEKFKMESIDQFHSIMQQLVYSLAIA 249

Query: 163 ETEV 166
           ETE+
Sbjct: 250 ETEL 253


>Z81547-4|CAB04458.1|  368|Caenorhabditis elegans Hypothetical
           protein F53F8.5 protein.
          Length = 368

 Score = 29.1 bits (62), Expect = 8.9
 Identities = 11/38 (28%), Positives = 23/38 (60%)

Query: 302 SRLRSEGDVTAPVASAAQHDAGKPVPADHKDVHLRFEE 339
           +R+ + G + A  +S+++H  GKP P  H+  H++  +
Sbjct: 89  ARITAPGALLASSSSSSEHRRGKPPPDRHEIYHVKMPD 126


>U00031-9|AAK18871.1|  470|Caenorhabditis elegans Hypothetical
           protein B0361.8 protein.
          Length = 470

 Score = 29.1 bits (62), Expect = 8.9
 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 118 VRYVYQPLDKLYMLLITTKASNILEDLETLRLFS--RVVPEYCVQLTETEVLN 168
           V  VY P D    L I + A ++LED +T+RL S  ++ PE   +L + EVL+
Sbjct: 252 VSIVYPPCDVEAFLNIESVAESLLEDTKTVRLLSVGQIRPEKNHKL-QLEVLH 303


  Database: celegans
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 12,573,161
  Number of sequences in database:  27,539
  
Lambda     K      H
   0.317    0.133    0.385 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 12,830,824
Number of Sequences: 27539
Number of extensions: 522902
Number of successful extensions: 1108
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1091
Number of HSP's gapped (non-prelim): 30
length of query: 571
length of database: 12,573,161
effective HSP length: 85
effective length of query: 486
effective length of database: 10,232,346
effective search space: 4972920156
effective search space used: 4972920156
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 62 (29.1 bits)

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