BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000104-TA|BGIBMGA000104-PA|IPR008968|Mu2 adaptin subunit (AP50) of AP2, IPR001392|Clathrin adaptor complex, medium chain, IPR011012|Longin-like (571 letters) Database: celegans 27,539 sequences; 12,573,161 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value U21309-2|AAN73882.1| 515|Caenorhabditis elegans Hypothetical pr... 400 e-111 AF003130-2|AAB54125.2| 426|Caenorhabditis elegans Adaptin, mu/m... 37 0.033 U53340-2|AAA96207.1| 142|Caenorhabditis elegans Ap-2 small chai... 34 0.31 AF016440-4|AAB65902.1| 157|Caenorhabditis elegans Adaptin, smal... 32 0.95 Z82069-7|CAB04907.2| 1792|Caenorhabditis elegans Hypothetical pr... 31 2.2 AL132902-15|CAC14425.1| 1792|Caenorhabditis elegans Hypothetical... 31 2.2 U39678-2|AAL16315.1| 133|Caenorhabditis elegans Hypothetical pr... 31 2.9 U33058-1|AAB00542.1| 6632|Caenorhabditis elegans UNC-89 protein. 31 2.9 AF003131-5|AAV34799.1| 5992|Caenorhabditis elegans Uncoordinated... 31 2.9 AF003131-4|AAB54132.2| 6632|Caenorhabditis elegans Uncoordinated... 31 2.9 AF003131-3|AAV34801.1| 7122|Caenorhabditis elegans Uncoordinated... 31 2.9 AF003131-2|AAV34800.1| 7441|Caenorhabditis elegans Uncoordinated... 31 2.9 AF003131-1|AAP68958.1| 8081|Caenorhabditis elegans Uncoordinated... 31 2.9 AF099001-8|AAP13778.1| 435|Caenorhabditis elegans Dumpy : short... 30 5.1 AF099001-7|AAP13777.1| 441|Caenorhabditis elegans Dumpy : short... 30 5.1 U70845-4|AAB09102.1| 340|Caenorhabditis elegans Hypothetical pr... 29 6.7 Z81547-4|CAB04458.1| 368|Caenorhabditis elegans Hypothetical pr... 29 8.9 U00031-9|AAK18871.1| 470|Caenorhabditis elegans Hypothetical pr... 29 8.9 >U21309-2|AAN73882.1| 515|Caenorhabditis elegans Hypothetical protein C13B9.3 protein. Length = 515 Score = 400 bits (984), Expect = e-111 Identities = 212/524 (40%), Positives = 319/524 (60%), Gaps = 26/524 (4%) Query: 65 LVLIAATVCTKSGKALVSRQFV-EMTKARIEGLLAAFPKLM-----TGGRQHTFVETESV 118 +VLIAA + +K+GK LV+RQFV +M ++R+EGL+ AFPKL+ RQHTFVET+SV Sbjct: 1 MVLIAACILSKTGKLLVARQFVNDMMRSRLEGLVDAFPKLIGNEKEAATRQHTFVETDSV 60 Query: 119 RYVYQPLDKLYMLLITTKASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFD 178 RYVY PLD +Y++L+TTK SNILEDLETLRLF RV+PEYC E E+L F+L+FAFD Sbjct: 61 RYVYHPLDNIYLVLVTTKNSNILEDLETLRLFVRVIPEYCRSNEEKEILAHDFDLIFAFD 120 Query: 179 EIVALGYRESVNLAQVRSFVEMDSHEEKIYQAVRQTQXXXXXXXXXXXXXXLQRERLEAA 238 E+V LGYRESVNLAQ+R+F EMDSHEE+++ +++ Q L+R + EA Sbjct: 121 EVVTLGYRESVNLAQIRTFTEMDSHEERVFMQIKEAQEKAAKQAMAEKAKELKRAQKEAL 180 Query: 239 KRGQPPRXXXXXXXXXXXXXXXXXXXXXXIAEKIPTTPARDTRTV-GRSAMKLGSRGTDA 297 RG P ++E P+ + G A+KLG + + Sbjct: 181 SRGLKP-----SYQSSTGISSSSTPNAAAVSEPAAPRPSAPKGPIGGGKALKLGGKTNNE 235 Query: 298 DSFVSRLRSEGDVTAPVASAAQHDAGKPVPA--------DHKDVHLRFEERLNLIAGRDG 349 D F+ LR +G APV A+ + A + VH+R EE++N RDG Sbjct: 236 DDFLDTLRQQGQSIAPVQKASLSGGVSSLAAPISTAPRVKREVVHVRTEEKINTRVSRDG 295 Query: 350 DIQTFELSGLLTLRISNEQFGRIHVHVDNKDSRPLQLQTHPNVDKEAFRSTGVIGLKQAQ 409 +++ E+ +TL I + +F I + ++N + QLQ HPN+DK+ ++S+ + +K Sbjct: 296 GLESGEVQATVTLSIGSPEFIPISIKMNNGSAAGTQLQVHPNLDKKEWQSSSTLKIKPNG 355 Query: 410 RPFPMHSDVGVLKWRLATTNDDKLAPLSVNCWPSEGVNGGCDVNIEYELEQDHLVLTDVN 469 +P+P++SDVG+LKW++A + +++L P+S NCWP E + G VNIEY L+++ + L +V Sbjct: 356 KPYPVNSDVGILKWKMALSEEEQL-PISFNCWPQES-SDGVQVNIEYTLQREDITLNNVR 413 Query: 470 ITIPLPSGNTSVVVHQWEGSYT-QKGRN-LIWSIPLVSKQQKTGSLEFTVTPSIPNDFFP 527 I +PLP+ T+ V + +G Y K +N ++WS+ ++ +G+LEF+V + FFP Sbjct: 414 IIVPLPTA-TAPSVGECDGEYEYHKTKNVIVWSLAVIDSSNSSGTLEFSVPNGHCDHFFP 472 Query: 528 LSVTWTSETSLALLTAVKVTQAEDGSPVDFSQEISFHADKYEFV 571 +SV +TSE +T KV + DGSPV +S E +F+++ +E V Sbjct: 473 VSVGFTSENLFVPITVQKVVK-NDGSPVTYSVETTFNSENFEIV 515 >AF003130-2|AAB54125.2| 426|Caenorhabditis elegans Adaptin, mu/medium chain (clathrinassociated complex) protein 1 protein. Length = 426 Score = 37.1 bits (82), Expect = 0.033 Identities = 26/123 (21%), Positives = 53/123 (43%), Gaps = 1/123 (0%) Query: 77 GKALVSRQFV-EMTKARIEGLLAAFPKLMTGGRQHTFVETESVRYVYQPLDKLYMLLITT 135 G ++SR + ++ + IE + + G + + + Y Y +Y++ I+ Sbjct: 13 GNVVISRNYRGDVDMSCIEKFMPLLVEKEDEGSASPVLVHQGISYTYIKYMNVYLVTISK 72 Query: 136 KASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALGYRESVNLAQVR 195 K +N++ L L V EY L E V + + FDE++ GY ++ ++ Sbjct: 73 KNTNVILVLSALYKIVEVFCEYFKTLEEEAVRDNFVIIYELFDEMLDFGYPQTTESKILQ 132 Query: 196 SFV 198 F+ Sbjct: 133 EFI 135 >U53340-2|AAA96207.1| 142|Caenorhabditis elegans Ap-2 small chain (clathrin associatedcomplex) protein 2 protein. Length = 142 Score = 33.9 bits (74), Expect = 0.31 Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 3/133 (2%) Query: 75 KSGKALVSRQFVEMTKARIEGLLAAFPKLMT-GGRQHT-FVETESVRYVYQPLDKLYMLL 132 ++GK +++ ++ + L+ +T +HT FVE + + VY+ LY + Sbjct: 10 RAGKTRLAKWYMHFDDDEKQKLIEEVHACVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCI 69 Query: 133 ITTKASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALG-YRESVNL 191 N L LE + F V+ EY + E +++ + + DE+ G RE+ Sbjct: 70 CVDITDNNLYYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQT 129 Query: 192 AQVRSFVEMDSHE 204 ++ + + S E Sbjct: 130 KVLKQLLMLTSLE 142 >AF016440-4|AAB65902.1| 157|Caenorhabditis elegans Adaptin, small chain (clathrinassociated complex) protein 1 protein. Length = 157 Score = 32.3 bits (70), Expect = 0.95 Identities = 25/116 (21%), Positives = 49/116 (42%), Gaps = 6/116 (5%) Query: 79 ALVSRQFVEMTKARIEGLLAAFPKLMTGGRQHTFVETESVRYVYQPLDKLYMLLITTKAS 138 A +Q ++ + I +LA PK+ F+E + ++ VY+ LY + Sbjct: 22 AYPDKQKKKICRELITQILARKPKMCA------FLEYKDLKVVYKRYASLYFCCAIEQND 75 Query: 139 NILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALGYRESVNLAQV 194 N L LE + + ++ +Y + E +++ F DE + G + + QV Sbjct: 76 NELITLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLAGEIQETSKKQV 131 >Z82069-7|CAB04907.2| 1792|Caenorhabditis elegans Hypothetical protein W04A8.7 protein. Length = 1792 Score = 31.1 bits (67), Expect = 2.2 Identities = 14/46 (30%), Positives = 25/46 (54%) Query: 484 HQWEGSYTQKGRNLIWSIPLVSKQQKTGSLEFTVTPSIPNDFFPLS 529 H+ +G YT+K + ++ + KQ++ +E T+ ND F LS Sbjct: 447 HRKDGQYTKKSKMILGQVQQRQKQEEDEQMESTMAQFTDNDPFNLS 492 >AL132902-15|CAC14425.1| 1792|Caenorhabditis elegans Hypothetical protein W04A8.7 protein. Length = 1792 Score = 31.1 bits (67), Expect = 2.2 Identities = 14/46 (30%), Positives = 25/46 (54%) Query: 484 HQWEGSYTQKGRNLIWSIPLVSKQQKTGSLEFTVTPSIPNDFFPLS 529 H+ +G YT+K + ++ + KQ++ +E T+ ND F LS Sbjct: 447 HRKDGQYTKKSKMILGQVQQRQKQEEDEQMESTMAQFTDNDPFNLS 492 >U39678-2|AAL16315.1| 133|Caenorhabditis elegans Hypothetical protein C39D10.8a protein. Length = 133 Score = 30.7 bits (66), Expect = 2.9 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 6/65 (9%) Query: 445 GVNGGCDVNIEYELEQDHLVLTDVNITIPLPSGNTSVVVHQ-WEGSYTQKGRNLIWSIPL 503 G+ G N E+++E TD ITI SV+ H+ WEG Y Q R+ I +P Sbjct: 67 GLGPGTTKNSEFKVEH-----TDNVITIRCKYRVQSVLAHETWEGEYIQYWRSEIGQMPK 121 Query: 504 VSKQQ 508 + + + Sbjct: 122 IIRDE 126 >U33058-1|AAB00542.1| 6632|Caenorhabditis elegans UNC-89 protein. Length = 6632 Score = 30.7 bits (66), Expect = 2.9 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 351 IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399 I T + + TL+ISN EQ G + V N +DS+ L+ PNV F+S Sbjct: 2121 ITTIKTEDVYTLKISNPKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175 >AF003131-5|AAV34799.1| 5992|Caenorhabditis elegans Uncoordinated protein 89, isoform e protein. Length = 5992 Score = 30.7 bits (66), Expect = 2.9 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 351 IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399 I T + + TL+ISN EQ G + V N +DS+ L+ PNV F+S Sbjct: 1481 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 1535 >AF003131-4|AAB54132.2| 6632|Caenorhabditis elegans Uncoordinated protein 89, isoform a protein. Length = 6632 Score = 30.7 bits (66), Expect = 2.9 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 351 IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399 I T + + TL+ISN EQ G + V N +DS+ L+ PNV F+S Sbjct: 2121 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175 >AF003131-3|AAV34801.1| 7122|Caenorhabditis elegans Uncoordinated protein 89, isoform g protein. Length = 7122 Score = 30.7 bits (66), Expect = 2.9 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 351 IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399 I T + + TL+ISN EQ G + V N +DS+ L+ PNV F+S Sbjct: 2121 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175 >AF003131-2|AAV34800.1| 7441|Caenorhabditis elegans Uncoordinated protein 89, isoform f protein. Length = 7441 Score = 30.7 bits (66), Expect = 2.9 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 351 IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399 I T + + TL+ISN EQ G + V N +DS+ L+ PNV F+S Sbjct: 1481 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 1535 >AF003131-1|AAP68958.1| 8081|Caenorhabditis elegans Uncoordinated protein 89, isoform b protein. Length = 8081 Score = 30.7 bits (66), Expect = 2.9 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 351 IQTFELSGLLTLRISN---EQFGRIHVHVDN---KDSRPLQLQTHPNVDKEAFRS 399 I T + + TL+ISN EQ G + V N +DS+ L+ PNV F+S Sbjct: 2121 ITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175 >AF099001-8|AAP13778.1| 435|Caenorhabditis elegans Dumpy : shorter than wild-typeprotein 23, isoform b protein. Length = 435 Score = 29.9 bits (64), Expect = 5.1 Identities = 16/71 (22%), Positives = 34/71 (47%) Query: 128 LYMLLITTKASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALGYRE 187 +++ +T + N E L+ F+ + Y +L E V N + DEI+ GY + Sbjct: 63 VWICAVTRQNVNAAMVFEFLKRFADTMQSYFGKLNEENVKNNFVLIYELLDEILDFGYPQ 122 Query: 188 SVNLAQVRSFV 198 + + +++F+ Sbjct: 123 NTDPGVLKTFI 133 >AF099001-7|AAP13777.1| 441|Caenorhabditis elegans Dumpy : shorter than wild-typeprotein 23, isoform a protein. Length = 441 Score = 29.9 bits (64), Expect = 5.1 Identities = 16/71 (22%), Positives = 34/71 (47%) Query: 128 LYMLLITTKASNILEDLETLRLFSRVVPEYCVQLTETEVLNQAFNLLFAFDEIVALGYRE 187 +++ +T + N E L+ F+ + Y +L E V N + DEI+ GY + Sbjct: 63 VWICAVTRQNVNAAMVFEFLKRFADTMQSYFGKLNEENVKNNFVLIYELLDEILDFGYPQ 122 Query: 188 SVNLAQVRSFV 198 + + +++F+ Sbjct: 123 NTDPGVLKTFI 133 >U70845-4|AAB09102.1| 340|Caenorhabditis elegans Hypothetical protein F22H10.5 protein. Length = 340 Score = 29.5 bits (63), Expect = 6.7 Identities = 27/124 (21%), Positives = 58/124 (46%), Gaps = 8/124 (6%) Query: 49 KIDKHSGPDCGLFKKQLVLIAATVCTKSGKALVSRQFVEMTKARIEGLLAAFPK--LMTG 106 K +H+ + + +L + + + A V+ FV+M A++ ++ P L Sbjct: 132 KCGEHTQGIDAVIAELAILKSLSALSTKNHANVTENFVKMVMAKV--VIGKHPTSLLKAW 189 Query: 107 GRQHTFVETESVRYVYQPLDKLYMLLITTKASNILE--DLETLRLFSRVVPE--YCVQLT 162 E+E++R ++LY++LI +K LE +E++ F ++ + Y + + Sbjct: 190 DTYRVEEESENIRPSKFNKNQLYLVLILSKGGTALEKFKMESIDQFHSIMQQLVYSLAIA 249 Query: 163 ETEV 166 ETE+ Sbjct: 250 ETEL 253 >Z81547-4|CAB04458.1| 368|Caenorhabditis elegans Hypothetical protein F53F8.5 protein. Length = 368 Score = 29.1 bits (62), Expect = 8.9 Identities = 11/38 (28%), Positives = 23/38 (60%) Query: 302 SRLRSEGDVTAPVASAAQHDAGKPVPADHKDVHLRFEE 339 +R+ + G + A +S+++H GKP P H+ H++ + Sbjct: 89 ARITAPGALLASSSSSSEHRRGKPPPDRHEIYHVKMPD 126 >U00031-9|AAK18871.1| 470|Caenorhabditis elegans Hypothetical protein B0361.8 protein. Length = 470 Score = 29.1 bits (62), Expect = 8.9 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Query: 118 VRYVYQPLDKLYMLLITTKASNILEDLETLRLFS--RVVPEYCVQLTETEVLN 168 V VY P D L I + A ++LED +T+RL S ++ PE +L + EVL+ Sbjct: 252 VSIVYPPCDVEAFLNIESVAESLLEDTKTVRLLSVGQIRPEKNHKL-QLEVLH 303 Database: celegans Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 12,573,161 Number of sequences in database: 27,539 Lambda K H 0.317 0.133 0.385 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 12,830,824 Number of Sequences: 27539 Number of extensions: 522902 Number of successful extensions: 1108 Number of sequences better than 10.0: 18 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 1091 Number of HSP's gapped (non-prelim): 30 length of query: 571 length of database: 12,573,161 effective HSP length: 85 effective length of query: 486 effective length of database: 10,232,346 effective search space: 4972920156 effective search space used: 4972920156 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 62 (29.1 bits)
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