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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000092-TA|BGIBMGA000092-PA|IPR007243|Autophagy protein
Apg6, IPR013819|Lipoxygenase, C-terminal
         (427 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B5A84 Cluster: PREDICTED: similar to beclin; n=...   532   e-150
UniRef50_Q9VCE1 Cluster: Beclin-1-like protein; n=8; Endopterygo...   466   e-130
UniRef50_A2A135 Cluster: Beclin1; n=9; Eumetazoa|Rep: Beclin1 - ...   399   e-110
UniRef50_Q14457 Cluster: Beclin-1; n=32; Tetrapoda|Rep: Beclin-1...   397   e-109
UniRef50_Q4S9N8 Cluster: Chromosome 2 SCAF14695, whole genome sh...   273   7e-72
UniRef50_UPI00001E2EF4 Cluster: PREDICTED: similar to hCG1642696...   240   4e-62
UniRef50_UPI00005A14AC Cluster: PREDICTED: similar to Beclin 1 (...   216   8e-55
UniRef50_Q5DI13 Cluster: SJCHGC05202 protein; n=3; Schistosoma|R...   190   5e-47
UniRef50_Q54JI9 Cluster: Putative uncharacterized protein atg6B;...   180   9e-44
UniRef50_Q4A187 Cluster: Beclin 1 protein; n=31; Magnoliophyta|R...   166   9e-40
UniRef50_Q9M367 Cluster: Beclin-1-like protein; n=3; Arabidopsis...   165   3e-39
UniRef50_Q6C9D9 Cluster: Yarrowia lipolytica chromosome D of str...   160   6e-38
UniRef50_A2R8L2 Cluster: Contig An16c0230, complete genome; n=8;...   159   2e-37
UniRef50_Q7SFX2 Cluster: Putative uncharacterized protein NCU031...   152   1e-35
UniRef50_A7KAI5 Cluster: Atg6p; n=1; Pichia angusta|Rep: Atg6p -...   152   2e-35
UniRef50_Q01AB5 Cluster: Autophagy protein beclin1; n=2; Ostreoc...   149   1e-34
UniRef50_Q4A1C2 Cluster: Beclin 1; n=5; Pezizomycotina|Rep: Becl...   145   2e-33
UniRef50_Q55CC5 Cluster: Autophagy protein 6; n=2; Dictyostelium...   132   2e-29
UniRef50_Q4A1C3 Cluster: Beclin 1; n=3; Saccharomycetaceae|Rep: ...   127   6e-28
UniRef50_Q0UVG4 Cluster: Putative uncharacterized protein; n=1; ...   122   2e-26
UniRef50_Q6CLQ7 Cluster: Kluyveromyces lactis strain NRRL Y-1140...   121   4e-26
UniRef50_Q1E5P9 Cluster: Putative uncharacterized protein; n=1; ...   121   4e-26
UniRef50_Q22592 Cluster: Beclin (Human autophagy) homolog protei...   120   6e-26
UniRef50_Q0DTB6 Cluster: Os03g0258500 protein; n=1; Oryza sativa...   119   2e-25
UniRef50_Q4P6J8 Cluster: Putative uncharacterized protein; n=1; ...   116   2e-24
UniRef50_P87117 Cluster: Uncharacterized protein C20G8.10c; n=2;...   109   1e-22
UniRef50_A5DIV5 Cluster: Autophagy-related protein 6; n=4; Sacch...   100   6e-20
UniRef50_Q02948 Cluster: Vacuolar protein sorting-associated pro...    99   1e-19
UniRef50_A7TQC4 Cluster: Putative uncharacterized protein; n=1; ...   100   1e-19
UniRef50_A5E3I5 Cluster: Putative uncharacterized protein; n=3; ...    96   2e-18
UniRef50_Q4A1C4 Cluster: Beclin 1; n=1; Clavispora lusitaniae|Re...    93   1e-17
UniRef50_Q5KKK1 Cluster: Putative uncharacterized protein; n=2; ...    92   3e-17
UniRef50_UPI00006CB2FF Cluster: hypothetical protein TTHERM_0045...    87   8e-16
UniRef50_A7TB90 Cluster: Predicted protein; n=2; Nematostella ve...    83   1e-14
UniRef50_Q6FP39 Cluster: Candida glabrata strain CBS138 chromoso...    79   2e-13
UniRef50_Q4A1C1 Cluster: Beclin 1; n=1; Saccharomyces castelli|R...    69   2e-10
UniRef50_A0DRK9 Cluster: Chromosome undetermined scaffold_60, wh...    66   2e-09
UniRef50_Q7YY64 Cluster: Beclin1-like protein, possible; n=3; Cr...    62   3e-08
UniRef50_A2WTT4 Cluster: Putative uncharacterized protein; n=3; ...    60   1e-07
UniRef50_Q5AFW0 Cluster: Putative uncharacterized protein VPS30;...    57   8e-07
UniRef50_A2EVY0 Cluster: Putative uncharacterized protein; n=1; ...    44   0.010
UniRef50_UPI0000F1E4DF Cluster: PREDICTED: hypothetical protein;...    42   0.023
UniRef50_UPI000049A39E Cluster: hypothetical protein 18.t00047; ...    36   1.5  
UniRef50_A7F0B5 Cluster: Putative uncharacterized protein; n=1; ...    36   2.7  
UniRef50_Q6YR34 Cluster: Isoleucyl-tRNA synthetase; n=4; Candida...    35   4.7  
UniRef50_Q6ZPK1 Cluster: MKIAA1686 protein; n=13; Euteleostomi|R...    34   6.2  
UniRef50_Q4XW84 Cluster: Cdc2-like protein kinase, putative; n=5...    34   6.2  
UniRef50_A2FQ97 Cluster: Putative uncharacterized protein; n=1; ...    34   6.2  
UniRef50_A6TJJ0 Cluster: Transposase IS66; n=1; Alkaliphilus met...    34   8.2  
UniRef50_A1ZYM6 Cluster: Possible surface protein, responsible f...    34   8.2  

>UniRef50_UPI00015B5A84 Cluster: PREDICTED: similar to beclin; n=2;
           Apocrita|Rep: PREDICTED: similar to beclin - Nasonia
           vitripennis
          Length = 448

 Score =  532 bits (1313), Expect = e-150
 Identities = 250/430 (58%), Positives = 310/430 (72%), Gaps = 6/430 (1%)

Query: 1   MSDSKTFVSFSCQRCLQPLKLDDSLNNLGEHTIADLTLQIRRNNEADLDLQSSSLDHYVP 60
           M D K+ V+F+CQRCLQPL+LD S N+LGEHTIA+L+L I+ +   +++ QS SL+H VP
Sbjct: 1   MVDMKSNVNFACQRCLQPLRLDPSFNHLGEHTIAELSLPIQHHVVREVEQQSGSLEHLVP 60

Query: 61  PFRMSESGNGANGFMVISDGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLE 120
           PFR++ES NG NGFM++ D  ET  L H L V+ATLFD+LS++S  DHPLCDECTD+LL 
Sbjct: 61  PFRLTESANGTNGFMLVGDSGETEGLSHHLRVRATLFDVLSSSSSADHPLCDECTDSLLM 120

Query: 121 LMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXW-----KQEQSRXXXXXXX 175
           LMD QL+ TE EW                                  K E+ R       
Sbjct: 121 LMDQQLRLTEGEWSDYNEYLKKLEAEQLQQGNEETEIEALEKELQDVKAEEERMIRELEA 180

Query: 176 XXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQ 235
                 A              L  E++ YWRE++++R+DL+  ED+ +  ECQLAY  SQ
Sbjct: 181 LRKEEAATKNAIAEQERERERLQSEEERYWREFSRHRRDLILAEDECRSLECQLAYAASQ 240

Query: 236 LEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARK 295
           LE+LKKTNVF ATFHI  SG FG IN+FRLGRLP+APVDWSEINAAWGQT LLL++LARK
Sbjct: 241 LERLKKTNVFNATFHIWHSGHFGTINSFRLGRLPSAPVDWSEINAAWGQTTLLLTALARK 300

Query: 296 INFNFQRYKLVPYGNHSYIEVLEDQKVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQFKE 355
           +N  FQR++LVP+GNHSYIEVL+  K LPLYGSGGF+FLWDTKFDAAMVAFLDCLQQFKE
Sbjct: 301 MNLTFQRFRLVPFGNHSYIEVLDQHKELPLYGSGGFKFLWDTKFDAAMVAFLDCLQQFKE 360

Query: 356 QVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWI 415
           QVE G++GFCLPYR+++GKIED+A+  ++YSIKIQFNSEE WTKALK++LTNLKW L W+
Sbjct: 361 QVEKGDSGFCLPYRMERGKIEDSAT-GNSYSIKIQFNSEEQWTKALKFLLTNLKWGLAWV 419

Query: 416 SSQFCEDKSE 425
           SSQF +D++E
Sbjct: 420 SSQFTKDEAE 429


>UniRef50_Q9VCE1 Cluster: Beclin-1-like protein; n=8;
           Endopterygota|Rep: Beclin-1-like protein - Drosophila
           melanogaster (Fruit fly)
          Length = 422

 Score =  466 bits (1148), Expect = e-130
 Identities = 219/421 (52%), Positives = 290/421 (68%), Gaps = 4/421 (0%)

Query: 1   MSDS-KTFVSFSCQRCLQPLKLDDSLNNLGEHTIADLTLQIRRNNEADLDLQ-SSSLDHY 58
           MS++ K  VSF+CQRCLQP+ LD+ L  +  H +A+L+L I  +N   LD Q +SS DH+
Sbjct: 1   MSEAEKQAVSFACQRCLQPIVLDEQLEKISVHAMAELSLPIYGDNGNTLDPQDASSFDHF 60

Query: 59  VPPFRMSESGNGANGFMVISDGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTL 118
           VPP+R+++S NG  GFM++SDG +   +     +KA LFD LS+NS +DHPLC+EC D++
Sbjct: 61  VPPYRLTDSINGT-GFMLVSDGRDNKKMSAAFKLKAELFDCLSSNSEIDHPLCEECADSM 119

Query: 119 LELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXWKQEQSRXXXXXXXXXX 178
           LE+MD +L+  E EW                             K+ + +          
Sbjct: 120 LEIMDRELRIAEDEWDVYKAYLDELEQQRVAPNVEALDKELDELKRSEQQLLSELKELKK 179

Query: 179 XXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEK 238
             +++N            L ++++ YWREYTK+R++LM TED  +  ECQ+AY++ QL+K
Sbjct: 180 EEQSLNDAIAEEEQEREELHEQEESYWREYTKHRRELMLTEDDKRSLECQIAYSKQQLDK 239

Query: 239 LKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINF 298
           L+ TN+F  TFHI  +G FG INNFRLGRLP+  VDWSEINAAWGQTVLLLS+LARKI  
Sbjct: 240 LRDTNIFNITFHIWHAGHFGTINNFRLGRLPSVSVDWSEINAAWGQTVLLLSALARKIGL 299

Query: 299 NFQRYKLVPYGNHSYIEVLEDQKVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQFKEQVE 358
            F+RY++VP+GNHSY+EVL + + LPLYGSGGF+F WDTKFDAAMVAFLDCL QF+++VE
Sbjct: 300 TFERYRVVPFGNHSYVEVLGENRELPLYGSGGFKFFWDTKFDAAMVAFLDCLTQFQKEVE 359

Query: 359 MGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWISSQ 418
             +T F LPY+++KGKI D  S  ++YSIKIQFNSEE WTKALK+MLTNLKW L W+SSQ
Sbjct: 360 KRDTEFLLPYKMEKGKIID-PSTGNSYSIKIQFNSEEQWTKALKFMLTNLKWGLAWVSSQ 418

Query: 419 F 419
           F
Sbjct: 419 F 419


>UniRef50_A2A135 Cluster: Beclin1; n=9; Eumetazoa|Rep: Beclin1 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 447

 Score =  399 bits (982), Expect = e-110
 Identities = 214/434 (49%), Positives = 262/434 (60%), Gaps = 24/434 (5%)

Query: 8   VSFSCQRCLQPLKLDDSLNNLGEHTIADLT---LQIRRNNEADLDLQSSSLDH------- 57
           VSF CQRC QPLKLD S N L   TI +LT   + +  N + D    SS  +        
Sbjct: 13  VSFVCQRCNQPLKLDTSFNVLDRMTIHELTAPLVMVTANKQQDSGESSSFPEETFLENKQ 72

Query: 58  ------YVPPFRMSESGNGANGFMVI---SDGWETTSLGHQLHVKATLFDLLSNNSYVDH 108
                 ++PP RM  S    N F +I   SDG    +L  +L V + LFD++S  + +DH
Sbjct: 73  DGVARKFIPPARMM-SAESTNSFTLIGEASDGGTMENLSRRLKVTSNLFDIMSGQTDIDH 131

Query: 109 PLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXWKQEQSR 168
           PLC+ECTDTLL+ +D QL  TE E                              KQE+  
Sbjct: 132 PLCEECTDTLLDHLDTQLNITENECQNYKSCLELLSQLPEEEEASLLNALQQL-KQEEES 190

Query: 169 XXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTEDQMKFYECQ 228
                        A+             +D E+  Y +EY ++++  +  +D +K  + Q
Sbjct: 191 LIQELESIETKREAVAKELDEGRNHSQLMDTEELRYQKEYCEFKRQQLELDDDLKSVDNQ 250

Query: 229 LAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLL 288
           + Y Q QL+KLKKTNVF ATFHI  SGQFG INNFRLGRLP+ PV+W+EINAAWGQTVLL
Sbjct: 251 MRYRQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLL 310

Query: 289 LSSLARKINFNFQRYKLVPYGNHSYIEVLEDQ-KVLPLYGSGGFRFLWDTKFDAAMVAFL 347
           L +LA K+   FQRY+LVPYGNHSY+E L D+ K LPLY SGG RF WD KFD AMVAFL
Sbjct: 311 LHALASKMGLCFQRYQLVPYGNHSYLESLSDKSKELPLYCSGGLRFFWDNKFDHAMVAFL 370

Query: 348 DCLQQFKEQVEMGNTGFCLPYR--IDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYML 405
           DC+QQFKE+VE  +TGFCLPYR  +DKGKIEDT     +YSIK QFNSEE WTKALK+ML
Sbjct: 371 DCVQQFKEEVEKDDTGFCLPYRMDVDKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFML 430

Query: 406 TNLKWALTWISSQF 419
           TNLKW L W+SSQF
Sbjct: 431 TNLKWGLAWVSSQF 444


>UniRef50_Q14457 Cluster: Beclin-1; n=32; Tetrapoda|Rep: Beclin-1 -
           Homo sapiens (Human)
          Length = 450

 Score =  397 bits (977), Expect = e-109
 Identities = 215/442 (48%), Positives = 264/442 (59%), Gaps = 26/442 (5%)

Query: 2   SDSKTFVSFSCQRCLQPLKLDDSLNNLGEHTIADLTLQIRRNNEA--------------- 46
           ++S   VSF CQRC QPLKLD S   L   TI +LT  +    +A               
Sbjct: 8   NNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEE 67

Query: 47  ---DLDLQSSSLDHYVPPFRMSESGNGANGFMVI---SDGWETTSLGHQLHVKATLFDLL 100
              +   Q      ++PP RM  S   AN F +I   SDG    +L  +L V   LFD++
Sbjct: 68  PFIETPRQDGVSRRFIPPARMM-STESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIM 126

Query: 101 SNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXX 160
           S  + VDHPLC+ECTDTLL+ +D QL  TE E                            
Sbjct: 127 SGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKE 186

Query: 161 XWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTED 220
              +E+ R            + +             LD+E+  Y REY+++++  +  +D
Sbjct: 187 LALEEE-RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245

Query: 221 QMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINA 280
           ++K  E Q+ Y Q+QL+KLKKTNVF ATFHI  SGQFG INNFRLGRLP+ PV+W+EINA
Sbjct: 246 ELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINA 305

Query: 281 AWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLEDQ-KVLPLYGSGGFRFLWDTKF 339
           AWGQTVLLL +LA K+   FQRY+LVPYGNHSY+E L D+ K LPLY SGG RF WD KF
Sbjct: 306 AWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKF 365

Query: 340 DAAMVAFLDCLQQFKEQVEMGNTGFCLPYRID--KGKIEDTASPPHAYSIKIQFNSEEHW 397
           D AMVAFLDC+QQFKE+VE G T FCLPYR+D  KGKIEDT     +YSIK QFNSEE W
Sbjct: 366 DHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQW 425

Query: 398 TKALKYMLTNLKWALTWISSQF 419
           TKALK+MLTNLKW L W+SSQF
Sbjct: 426 TKALKFMLTNLKWGLAWVSSQF 447


>UniRef50_Q4S9N8 Cluster: Chromosome 2 SCAF14695, whole genome
           shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2
           SCAF14695, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 383

 Score =  273 bits (669), Expect = 7e-72
 Identities = 138/250 (55%), Positives = 174/250 (69%), Gaps = 34/250 (13%)

Query: 204 YWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLE----------------KLKKT----- 242
           Y +EY+++++  +  +D++K  + Q+ Y Q QL+                K+  T     
Sbjct: 131 YQKEYSEFKRQQLELDDELKSVDNQMRYCQIQLDRLKKTNVFNATFHIWYKITHTPRVDA 190

Query: 243 ------NVFKATFHIS----DSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSL 292
                 N+++ T ++      SGQFG INNFRLGRLP+ PV+W+EINAAWGQTVLLL +L
Sbjct: 191 LFSPFLNIYRRTQNVPVLFRHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHAL 250

Query: 293 ARKINFNFQRYKLVPYGNHSYIEVLEDQ-KVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQ 351
           A K+   F+RY+LVPYGNHSY+E L D+ K LPLY SGG RF WD KFD AMVAFLDC+Q
Sbjct: 251 ANKMGLRFKRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQ 310

Query: 352 QFKEQVEMGNTGFCLPYRID--KGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLK 409
           QFKE+VE G+TGFCLPYR+D  KGKIEDT     +YSIK QFNSEE WTKALK+MLTNLK
Sbjct: 311 QFKEEVEKGDTGFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLK 370

Query: 410 WALTWISSQF 419
           W L W++SQF
Sbjct: 371 WGLAWVTSQF 380



 Score = 42.3 bits (95), Expect = 0.023
 Identities = 22/37 (59%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 2  SDSKTF-VSFSCQRCLQPLKLDDSLNNLGEHTIADLT 37
          S S T  VSF CQRC QPLKLD S N L   T+ +LT
Sbjct: 6  SSSTTMQVSFVCQRCCQPLKLDTSFNVLDRVTVQELT 42


>UniRef50_UPI00001E2EF4 Cluster: PREDICTED: similar to hCG1642696;
           n=1; Mus musculus|Rep: PREDICTED: similar to hCG1642696
           - Mus musculus
          Length = 447

 Score =  240 bits (588), Expect = 4e-62
 Identities = 129/360 (35%), Positives = 187/360 (51%), Gaps = 5/360 (1%)

Query: 65  SESGNGANGFMVISDGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDN 124
           +  GN    F ++ +     ++    +     F++LS+   VDHPLC +CTD LL  +D+
Sbjct: 82  TSQGNACCTFTLLGESASMRTMNTIQNTVLETFEILSDQKVVDHPLCVDCTDHLLMQLDD 141

Query: 125 QLKQTEAE---WXXXXXXXXXXXXXXXXXXXXXXXXXXXXWKQEQSRXXXXXXXXXXXXR 181
           QL    ++   +                             +QE++R             
Sbjct: 142 QLALLASDNQKYKSFQDRELLVSEEEREALHAELCAELSSLEQEEARLTQELEDLDGHHA 201

Query: 182 AMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKK 241
            +             L K+ + +  EY+ ++ + +   DQ+   E QL Y  SQ  +L++
Sbjct: 202 RVAAELRAAQAESKELYKQHEQHRVEYSVFKMEQLELMDQLSSVENQLTYALSQQYRLRQ 261

Query: 242 TNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQ 301
           TN+F ATF ISD G  G+INNFRLG LP   V W+EI++AWGQTVLLL SL++     FQ
Sbjct: 262 TNIFNATFTISDEGPLGVINNFRLGCLPGVRVGWTEISSAWGQTVLLLFSLSKIAGLQFQ 321

Query: 302 RYKLVPYGNHSYIEVLEDQKVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQFKEQVEMGN 361
           RY+LVP+G+HSY++ L    VLPL+  G      + KFD  M AFLDCLQQF E++E   
Sbjct: 322 RYQLVPFGDHSYLKSLTGDGVLPLFSDGSHSVFLNNKFDCGMKAFLDCLQQFVEEIERDE 381

Query: 362 TGFCLPYRI--DKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWISSQF 419
              CLPYRI   +G +ED        SI+   N+EE W++ALK+ML++LK  L W S +F
Sbjct: 382 RCPCLPYRIHVKEGLMEDVWDSGECCSIRTHLNTEEEWSRALKFMLSDLKLILAWASLRF 441


>UniRef50_UPI00005A14AC Cluster: PREDICTED: similar to Beclin 1
           (Coiled-coil myosin-like BCL2-interacting protein)
           (Protein GT197); n=1; Canis lupus familiaris|Rep:
           PREDICTED: similar to Beclin 1 (Coiled-coil myosin-like
           BCL2-interacting protein) (Protein GT197) - Canis
           familiaris
          Length = 452

 Score =  216 bits (528), Expect = 8e-55
 Identities = 130/391 (33%), Positives = 192/391 (49%), Gaps = 22/391 (5%)

Query: 8   VSFSCQRCLQPLKLDDSLNNLGEHTI---ADLTLQIRRNNEADLDLQSSSLDHYVPPFRM 64
           + F CQ C QP++L  S   LG  T    A  T    +    +  ++  +    +   ++
Sbjct: 4   IRFICQGCRQPMRLSQSTGTLGLETTQRPAASTFTSAQQEPRETLVRGPTSKVEIDTEKL 63

Query: 65  SES------------GNGANGFMVISDGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCD 112
            ++            G+    F+++       +L +  +    +FD+L+   YVDHPLC+
Sbjct: 64  PDASCSTLPGDGKMFGDSPKNFILLGKFDSARTLSNIQNTTRDIFDILTGEKYVDHPLCE 123

Query: 113 ECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXWKQEQSRXXXX 172
           +CTD LLE++D QL   ++E                              + E++R    
Sbjct: 124 DCTDKLLEVLDTQLIIVDSE----NEHYKYWRGRICEEEMKTLQEELEGLELEEARLVQE 179

Query: 173 XXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYT 232
                     +             L+++   YW++Y+  +   +  +D++K  E QL + 
Sbjct: 180 LKEVENKQERVAEDLEAAQAETEMLEQQDKQYWKDYSNLKWQQLELQDELKSMERQLRHA 239

Query: 233 QSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSL 292
           Q Q  +LKKT+VF ATF I   G  GIIN+FRLG LPT PV W EIN AWGQT LLL +L
Sbjct: 240 QIQWGRLKKTSVFSATFEIRYDGPVGIINSFRLGCLPTVPVSWKEINMAWGQTALLLLAL 299

Query: 293 ARKINFNFQRYKLVPYGNHSYIEVLEDQKV-LPLYGSGGFRFLWDTKFDAAMVAFLDCLQ 351
           + KI   F+RY+L+P GN SY++ L +  V LPL+         D KFD AM+AFLDC+Q
Sbjct: 300 SNKIGLEFRRYQLIPCGNRSYLKSLTNDPVELPLFCIMRQSTCLDLKFDQAMMAFLDCMQ 359

Query: 352 QFKEQVEMGNTGFCLPYRI--DKGKIEDTAS 380
           QFKE+ E G  G CLP RI    G +ED+ S
Sbjct: 360 QFKEEAEKGKWGLCLPCRIHVKNGLMEDSGS 390


>UniRef50_Q5DI13 Cluster: SJCHGC05202 protein; n=3; Schistosoma|Rep:
           SJCHGC05202 protein - Schistosoma japonicum (Blood
           fluke)
          Length = 587

 Score =  190 bits (464), Expect = 5e-47
 Identities = 99/222 (44%), Positives = 136/222 (61%), Gaps = 5/222 (2%)

Query: 199 KEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFG 258
           +E D    +Y   +  L+  E++M+  E +L+Y +S L +L++TNV    F I   G  G
Sbjct: 354 EELDRATTQYNDQKLALIEAEEEMQCLESRLSYARSHLHRLQRTNVLNIAFPIWYDGHIG 413

Query: 259 IINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLE 318
           +IN   LGRLP  PV W EINAAWGQ  LLL  + +K+N++FQ Y +VP G+ S +  L 
Sbjct: 414 VINGLHLGRLPNRPVGWEEINAAWGQCALLLQCIGKKLNYSFQSYLIVPMGSQSKVVQLS 473

Query: 319 DQKVLPL-YGSGGFRFLWDTKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRI-DKGKIE 376
             K  PL Y +GG R L   KFD AM+ FLDCL Q ++ +E   +   LP+RI DKGKI+
Sbjct: 474 ISKEFPLYYTTGGMRILSAGKFDTAMINFLDCLNQAQQIIE-HTSSIQLPFRIKDKGKIQ 532

Query: 377 DTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWISSQ 418
           D       YSI+   NSEE+WTKALK ML N+KW +  +S++
Sbjct: 533 DPDG--QIYSIRWNGNSEENWTKALKMMLINMKWIIAALSAK 572



 Score = 63.7 bits (148), Expect = 9e-09
 Identities = 46/131 (35%), Positives = 66/131 (50%), Gaps = 10/131 (7%)

Query: 12  CQRCLQPLKLDDSLNNLGEH---TIADLTLQIRRNNEAD--LDLQSSSLDH---YVPP-F 62
           CQRC  PL+LD    +L +    T+ D T      +++   + +++S+       VPP  
Sbjct: 32  CQRCFNPLQLDHDFEHLQKTELMTLIDATTTDSETSDSINLVPVRNSTAPRPRFIVPPNS 91

Query: 63  RMSESGNGANGFMVI-SDGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLEL 121
            +S   +  N    + S    T+SL H+L V A LFD+LS  + VDHPLC EC DTLL  
Sbjct: 92  ALSLLNDDENPLETLHSYAGPTSSLDHRLKVNACLFDVLSGRTEVDHPLCQECADTLLLA 151

Query: 122 MDNQLKQTEAE 132
               L+  E E
Sbjct: 152 KQQCLEFQEEE 162


>UniRef50_Q54JI9 Cluster: Putative uncharacterized protein atg6B;
           n=1; Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein atg6B - Dictyostelium discoideum
           AX4
          Length = 855

 Score =  180 bits (437), Expect = 9e-44
 Identities = 97/326 (29%), Positives = 157/326 (48%), Gaps = 12/326 (3%)

Query: 95  TLFDLLSNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXX 154
           +LF + ++    D PLC ECT   +  ++++    + E                      
Sbjct: 489 SLFKIATDLINYDLPLCLECTKLTIGELEDEGSILDGEVSIYSAYLKQLEKGKTEEDLEE 548

Query: 155 XXXXXXXWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKD 214
                    +E+ +            + +             L   +D YW  ++++  +
Sbjct: 549 LGKEMTLLCEEEEQLRLMIENTHQERKEVEQLTLQLQDRIATLKSLEDSYWSCFSEFHYE 608

Query: 215 LMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVD 274
               +D+      Q+ +    LE LK+TN+    FH+   G FG IN+ RLG+LP+ PV+
Sbjct: 609 TFRNKDERDQTTVQIQWVNDHLESLKQTNILNDAFHLWHDGHFGTINSLRLGKLPSQPVE 668

Query: 275 WSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEV--LEDQKVLPLYGSGGF- 331
           W+EINAAWG  V LL ++A+K+ F FQ++ LVP G+ S ++   ++      LYG+    
Sbjct: 669 WNEINAAWGLAVSLLDAMAKKLKFKFQQFTLVPNGSCSRVDKRDVDPPLAYELYGTNDIS 728

Query: 332 --RFLWDTKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKI 389
             R  W  +FD  M+AFL C+++  E +   +  F +PY+IDK  I           IK+
Sbjct: 729 LGRLFWYRRFDNGMIAFLQCIKELCEHITEKDPEFSVPYKIDKEYI-------GGMCIKL 781

Query: 390 QFNSEEHWTKALKYMLTNLKWALTWI 415
           QF +++ WTK+LK+MLTNLKW L WI
Sbjct: 782 QFTNDDTWTKSLKFMLTNLKWILIWI 807


>UniRef50_Q4A187 Cluster: Beclin 1 protein; n=31; Magnoliophyta|Rep:
           Beclin 1 protein - Solanum lycopersicum (Tomato)
           (Lycopersicon esculentum)
          Length = 523

 Score =  166 bits (404), Expect = 9e-40
 Identities = 103/328 (31%), Positives = 153/328 (46%), Gaps = 20/328 (6%)

Query: 97  FDLLSNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXX 156
           FD+ +  + ++ PLC EC   L + +D +++    +                        
Sbjct: 167 FDIATTQTQIEQPLCLECMRVLSDKLDKEVEDVNRDIQAYEACLHQLEGEARNVLSEADF 226

Query: 157 XXXXXWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKE-QDVYWREYTKYRKDL 215
                  +E+ R             A+               KE ++ YW E+  ++  L
Sbjct: 227 LKEKLKIEEEERKLETAIEETEKQCAVVTAELKELEMKSSRFKELEERYWHEFNNFQFQL 286

Query: 216 MTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDW 275
           ++ +++      +   +Q+ LE LK+TNV    F I   G+FG INNFRLGRLP  PV+W
Sbjct: 287 ISHQEERDAILAKTEVSQAHLELLKRTNVLNDAFPIWYDGEFGTINNFRLGRLPKIPVEW 346

Query: 276 SEINAAWGQTVLLLSSLARKINFNFQ-RYKLVPYGNHSYIEVLEDQKVLPLYGSGGFRFL 334
            EINAAWGQ  LLL ++A+     FQ R K++P G++  I +  +     L+G       
Sbjct: 347 DEINAAWGQACLLLHTMAQHFRPKFQYRIKIIPMGSYPPI-IDTNNTTYELFGP--VNLF 403

Query: 335 WDTKFDAAMVAFLDCLQ---QFKEQVEMGNT-----GFCLPYRIDKGKIEDTASPPHAYS 386
           W T+ D AM  FL CL+   +F    +  N       F LPY+I+  K+E       +YS
Sbjct: 404 WSTRDDKAMTLFLICLKGVSEFANSKDRENNIRPDKCFKLPYKIENDKVE-------SYS 456

Query: 387 IKIQFNSEEHWTKALKYMLTNLKWALTW 414
           I   FN +E+WTKALKY L NLKW L W
Sbjct: 457 ITQSFNKQENWTKALKYTLCNLKWVLYW 484


>UniRef50_Q9M367 Cluster: Beclin-1-like protein; n=3; Arabidopsis
           thaliana|Rep: Beclin-1-like protein - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 517

 Score =  165 bits (400), Expect = 3e-39
 Identities = 104/342 (30%), Positives = 156/342 (45%), Gaps = 20/342 (5%)

Query: 83  TTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXX 142
           T+     ++V    FD+    + V+ PLC EC   L + ++ +++    +          
Sbjct: 144 TSGFNATINVLTRAFDIARTQTQVEQPLCLECMRVLSDKLEKEVEDVTRDVEAYEACVQR 203

Query: 143 XXXXXXXXXXXXXXXXXXXWKQEQSRXXXXXXXXXXXXRA-MNXXXXXXXXXXXXLDKEQ 201
                                +E+ R             A +N             ++ +
Sbjct: 204 LEGETQDVLSEADFLKEKKKIEEEERKLVAAIEETEKQNAEVNHQLKELEFKGNRFNELE 263

Query: 202 DVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIIN 261
           D YW+E+  ++  L+  +++      ++  +Q+ LE L KTNV    F I + G+FG IN
Sbjct: 264 DRYWQEFNNFQFQLIAHQEERDAILAKIEVSQAHLELLNKTNVLIDAFPIRNDGEFGTIN 323

Query: 262 NFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQ-RYKLVPYGNHSYIEVLEDQ 320
           NFRLGRLP   V+W EINAAWGQ  LLL ++       FQ + K+ P G++  I V  + 
Sbjct: 324 NFRLGRLPAIKVEWDEINAAWGQACLLLHTMCNYFRPKFQCQVKIQPMGSYPRI-VDSNN 382

Query: 321 KVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQF------KEQVEMGNTGFC--LPYRIDK 372
           +   L+G       W T++D AM  +L CL+ F      K+Q        C  LPY+I+K
Sbjct: 383 ETYELFGP--VNLFWSTRYDKAMTLYLMCLKDFADFANSKDQENNIPPDNCLNLPYKIEK 440

Query: 373 GKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTW 414
            K+         YSI   FN +E WTKALKY L NLKWAL W
Sbjct: 441 DKV-------LGYSITQSFNKQESWTKALKYTLCNLKWALYW 475


>UniRef50_Q6C9D9 Cluster: Yarrowia lipolytica chromosome D of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome D of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 434

 Score =  160 bits (389), Expect = 6e-38
 Identities = 122/437 (27%), Positives = 185/437 (42%), Gaps = 37/437 (8%)

Query: 12  CQRCLQPLKLDDSLNNLGEHTIADLTLQIRRNN---EADLDLQSSSLDHY--VPPFRMSE 66
           CQRC  PL   DSL +L +  +  L  +  +N    E++ +L   +LD +       +  
Sbjct: 4   CQRCKLPLAYGDSLLDLNQAQMKTLQTKAEQNKPDGESNTNLDPQALDKFNRARETALKR 63

Query: 67  SGNGANGFMVISDGW----------------ETTSLGHQLHVKATLFDLLSNNSYVDHPL 110
                + F+ +S                   ++ S+  ++    TLFD++S+ S +D P+
Sbjct: 64  GTMSGDSFVFLSQSQVGHTPPNPNNVKTTASDSNSISTRITALETLFDVISSTSSIDFPI 123

Query: 111 CDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXWKQ-EQSRX 169
           C +C D + E +  + +QT  E                               + E+   
Sbjct: 124 CTDCGDQIREGLKTRFEQTSKERDVFARFLNKLRDSDGEEEDLAVKQRELEKLEGEKEAA 183

Query: 170 XXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTEDQMKFYECQL 229
                        +             L+ ++  +W+   +   D+   + +      Q 
Sbjct: 184 LSELKSQEKELDELEKEIQALEKEKTDLESQEPRFWQLQNELYLDIEEHKQERDSLITQY 243

Query: 230 AYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLL 289
              + + EKL K NV+   F I   G FG IN  RLGRL    V+WSEINAAWGQT+ LL
Sbjct: 244 RNLKDEQEKLSKVNVYNDAFCIGHDGYFGTINGLRLGRLKNRMVEWSEINAAWGQTLFLL 303

Query: 290 SSLARKINFNFQRYKLVPYGNHSYIEVLEDQKVL----PLYGSGGF---RFLWDTKFDAA 342
           +++  K+ F    YKL P G  S I+   D   +     L+ SG +   R L   K D A
Sbjct: 304 ATVCHKLGFKLSGYKLHPMGGVSRIDKYSDTDGVVTSQELFSSGDYSFERILNHKKLDNA 363

Query: 343 MVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQFN-SEEHWTKAL 401
           MV+ L  LQQ  E VE  +    LPYRI K KI          SI++  N S + WT A 
Sbjct: 364 MVSVLAVLQQIGEYVESLDPSLKLPYRISKDKI-------GGISIRLSINASNDSWTTAC 416

Query: 402 KYMLTNLKWALTWISSQ 418
           KY+LTN KW L + S++
Sbjct: 417 KYVLTNAKWLLAFTSTR 433


>UniRef50_A2R8L2 Cluster: Contig An16c0230, complete genome; n=8;
           Eurotiomycetidae|Rep: Contig An16c0230, complete genome
           - Aspergillus niger
          Length = 568

 Score =  159 bits (385), Expect = 2e-37
 Identities = 117/380 (30%), Positives = 168/380 (44%), Gaps = 49/380 (12%)

Query: 80  GWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXX 139
           G +  S   Q+   + LFD++S  S +DHP+C ECT+ L++ +  +L     E       
Sbjct: 163 GPDDASFADQVERTSRLFDIISARSDIDHPICTECTEMLVDGLQQRLVDATKERDAYISF 222

Query: 140 XXXXXXXXXXXXXXXXXXXXXXWKQEQSRXXXXXXXXXXXXR-AMNXXXXXXXXXXXXLD 198
                                    +  +            + A++            LD
Sbjct: 223 LRNLNSSVPTAEELEAAQKSLQETLDAEKLAFEELLALEIEKQALDEEIAGLEEEARQLD 282

Query: 199 KEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFG 258
            E++ +WR+   +   L   +++      +  +   QLE+L++TNV+   F I   G FG
Sbjct: 283 LEEEKFWRDRNSFALTLSDFQNERDALNMKYDHDSRQLERLQRTNVYNDAFCIGHDGYFG 342

Query: 259 IINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLE 318
            IN  RLGRL    VDW EINAAWGQT LLL+++A K+ F FQ Y++ P G+ S IE +E
Sbjct: 343 TINGLRLGRLANPSVDWPEINAAWGQTALLLATIADKLGFQFQGYQIKPMGSMSRIEKIE 402

Query: 319 DQK----------------------VLPLYGSG--GFRFLW-DTKFDAAMVAFLDCLQQF 353
             +                      VL L+ SG       W   +FDA MVAFL+CL+Q 
Sbjct: 403 QSRPSPAQSALSGANAMSSAPPKITVLDLFSSGELPLNLPWLHRRFDAGMVAFLECLRQL 462

Query: 354 KEQVE------------MGNT---GFCLPYRIDKGKIEDTASPPHAYSIKIQFN-SEEHW 397
            E VE              NT   G  LPY I + KI D        SIK+ FN ++E W
Sbjct: 463 GEFVEKTPVPVPSNRRGQANTAVPGLKLPYEIKRDKIGDA-------SIKLGFNQNDETW 515

Query: 398 TKALKYMLTNLKWALTWISS 417
           T+A KY LT  K+ L   S+
Sbjct: 516 TRACKYTLTCCKFLLAHASN 535


>UniRef50_Q7SFX2 Cluster: Putative uncharacterized protein
           NCU03122.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU03122.1 - Neurospora crassa
          Length = 465

 Score =  152 bits (369), Expect = 1e-35
 Identities = 112/378 (29%), Positives = 161/378 (42%), Gaps = 42/378 (11%)

Query: 79  DGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXX 138
           D      L  Q+     LF+++S  S +DHP+C EC+D L+E M  +L+    E      
Sbjct: 76  DDMANAHLSDQMERILKLFEVISARSDIDHPICIECSDMLVEEMQKKLESANREKDAYVN 135

Query: 139 XXXXXXXXX-XXXXXXXXXXXXXXWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXL 197
                                    KQ +               A+             +
Sbjct: 136 YLKELKASEPTDEEIRAQEEATRKAKQAEKELLEELKALEQEQAALEREKLELEAEIREV 195

Query: 198 DKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQF 257
           D +++ +WR    +   L+  +++      +  +   QLEKL+++NVF  TF IS  G F
Sbjct: 196 DIKEEEFWRARNGFNTTLIDFQNERDSINSKFDHDSRQLEKLQRSNVFNDTFCISHDGTF 255

Query: 258 GIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVL 317
             IN  RLGR+   PVDW EINAAWG  +LLL ++A K+NF F+ Y+  P G+ S I  +
Sbjct: 256 ATINGLRLGRMHNVPVDWPEINAAWGHALLLLVTVAEKLNFRFEGYEPQPMGSTSRIVRI 315

Query: 318 E-------------------------DQKVLPLYGSG----GFRFLWDTKFDAAMVAFLD 348
           E                          + VL LY SG    GF F+   KFD AMVAFL+
Sbjct: 316 EPASTSMASSFYPSRPVDANAPPPPAKRTVLELYSSGDFPLGFTFI-HRKFDTAMVAFLE 374

Query: 349 CLQQF----KEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYM 404
            ++Q     +EQ         LPY+I   KI D        SIK+    ++ W KA K  
Sbjct: 375 LVRQLGVHVQEQTRREGNPLSLPYQIQGDKISDV-------SIKLGVQQDDSWAKACKLT 427

Query: 405 LTNLKWALTWISSQFCED 422
           LT  K+ L   S+ +  D
Sbjct: 428 LTCCKFLLAHASNSWLHD 445


>UniRef50_A7KAI5 Cluster: Atg6p; n=1; Pichia angusta|Rep: Atg6p -
           Pichia angusta (Yeast) (Hansenula polymorpha)
          Length = 443

 Score =  152 bits (368), Expect = 2e-35
 Identities = 114/441 (25%), Positives = 188/441 (42%), Gaps = 42/441 (9%)

Query: 10  FSCQRCLQPLKLDDSLNNLGEHTIADLTLQI--RRNNEADLDLQSSSL--DHYVPPFRMS 65
           ++CQRC  PL +DDSL  L       LTL    R N +   DL    +     V  F  +
Sbjct: 4   YTCQRCKLPLVIDDSLQGLSNAQKHLLTLSYGQRPNEDHPKDLNEYPILPAERVALFEEA 63

Query: 66  ESGNGAN----------------GFMVISD----GWETTSLGHQLHVKATLFDLLSNNSY 105
              +G+                  F+++ D      +  S+  ++     +F++LS+   
Sbjct: 64  SKTSGSKPLVSSKGSEALHIDDGSFVILEDKDQPSMDKVSVSERVASLDNIFNILSSKYE 123

Query: 106 VDHPLCDECTDTLLELMDNQLKQT--EAEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXWK 163
           +D+P+C +C  TL+E +  Q +Q   E +                              K
Sbjct: 124 IDYPVCTDCASTLIEELKQQFEQMTKEKDTYVQFLKKLTAQSGPNRKKAQDSLSELALLK 183

Query: 164 QEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTEDQMK 223
           +E+++              +             L+ ++  +  +   Y  +L+   ++ +
Sbjct: 184 EEETKLLEELEKAEREQEELTQQLVEVEQELEDLENQEKEFCLQKNAYDLELIEFVNERE 243

Query: 224 FYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWG 283
             +    Y  ++L+ L+KTNVF   F IS   QFG IN  RLG L    V W EINAA G
Sbjct: 244 RIKASYEYNLNRLDSLRKTNVFNDVFMISHDDQFGTINGLRLGNLDNVKVSWHEINAALG 303

Query: 284 QTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLE-------DQKVLPLYGSGGF---RF 333
           Q  LLL+++ R ++F    Y+++P G+ S IE           ++ L L+ SG F   + 
Sbjct: 304 QLALLLATVVRILDFQLDGYRIIPMGSTSRIEKYRKDRNGSISKQTLDLFSSGEFSIGKI 363

Query: 334 LWDTKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQFNS 393
               + DA MVA +D + Q   +++  +    LPY++ + K+      P A S      S
Sbjct: 364 FTHNQLDAGMVALVDIVSQIGRKLKQLDESNDLPYKMTEDKVAGYPIKPSARS------S 417

Query: 394 EEHWTKALKYMLTNLKWALTW 414
            E WT A +Y+LTN KW LT+
Sbjct: 418 NEEWTSACRYLLTNAKWILTY 438


>UniRef50_Q01AB5 Cluster: Autophagy protein beclin1; n=2;
           Ostreococcus|Rep: Autophagy protein beclin1 -
           Ostreococcus tauri
          Length = 454

 Score =  149 bits (362), Expect = 1e-34
 Identities = 86/226 (38%), Positives = 123/226 (54%), Gaps = 16/226 (7%)

Query: 197 LDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQ 256
           LD+ +D YWRE+  ++++L +  ++      +    Q+ L++L+KTNVF  +FHI   G 
Sbjct: 236 LDEAEDTYWREFHAFKRNLNSHLEKRDSILTRTEQAQAHLDRLEKTNVFNDSFHIWTDGA 295

Query: 257 FGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEV 316
           FG IN FRLGRLP   V+W EINAA+G   LLL S+AR   F F +Y L P G+   +  
Sbjct: 296 FGTINGFRLGRLPNVMVEWDEINAAFGLACLLLHSMARICKFTFTQYTLKPMGSFPKVSD 355

Query: 317 LEDQKVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQFKE-----QVEMG-NTGFCLPYRI 370
             +  V  L+G      +   K+D A++ FL CL +  E      V  G N  F LP+ I
Sbjct: 356 -ANGGVFELFGP--VSIISSHKYDKAVLGFLTCLSELSEFMKARDVRQGVNPPFQLPFTI 412

Query: 371 DKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWIS 416
              K++          +   FN +E+WT ALK MLT+LK  L W+S
Sbjct: 413 SNDKVD-------GKKMSFTFNRDENWTYALKLMLTDLKLMLAWLS 451



 Score = 41.9 bits (94), Expect = 0.031
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 2/69 (2%)

Query: 64  MSESGNGANGFMVISDGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMD 123
           +S  G     F+V+ +  E +  G +  V A +FD+ S  S  DHPLCD C+   L  ++
Sbjct: 94  VSREGGMEASFVVLPERAEKS--GIEPSVMARVFDVASELSERDHPLCDACSSLALTEVE 151

Query: 124 NQLKQTEAE 132
            + ++ EAE
Sbjct: 152 RRTREVEAE 160


>UniRef50_Q4A1C2 Cluster: Beclin 1; n=5; Pezizomycotina|Rep: Beclin
           1 - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 502

 Score =  145 bits (352), Expect = 2e-33
 Identities = 106/348 (30%), Positives = 156/348 (44%), Gaps = 34/348 (9%)

Query: 96  LFDLLSNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXX 155
           LF++LS  S +DHP+C ECTD L+E +  +L+    E                       
Sbjct: 146 LFEILSARSDIDHPVCVECTDILVEGLRKRLESASRERTTYVNFLKKLELESPTDDELKA 205

Query: 156 XXXXXXWKQEQSRXXXXXXXXXXXXRA-MNXXXXXXXXXXXXLDKEQDVYWREYTKYRKD 214
                   +EQ              +A ++            +D E++ +WRE   +   
Sbjct: 206 QEEALAKAKEQEAAALKELVALEKEKASLDDEILALEEESRRMDAEEEQFWRERNAFASQ 265

Query: 215 LMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVD 274
           L   +++      +  +    L+ L++TNV+  TF IS  G F  IN  RLGRL   PVD
Sbjct: 266 LADFQNERDSINSKYDHDARLLQSLQRTNVYNDTFLISHDGTFATINGLRLGRLHNTPVD 325

Query: 275 WSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLE---------------- 318
           W EINAAWG  +LL++++A K+ + F  Y+  P G+ S I   E                
Sbjct: 326 WPEINAAWGHALLLVATVADKLQYRFDGYEPQPMGSMSRIIRFEPPSPAASRVGSAPPQA 385

Query: 319 -DQKVLPLYGSG----GFRFLWDTKFDAAMVAFLDCLQQ---FKEQVEMGN-TGFCLPYR 369
             +KVL LY SG    G  F+   K DAAMVA+L+ ++Q   F  +    N     LPY 
Sbjct: 386 PKKKVLELYSSGDMPLGLTFM-HRKLDAAMVAYLELVRQLGMFMVRTTTANGKPLTLPYV 444

Query: 370 IDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWISS 417
           ID  KI       +  SIK+    ++ WTKA K++LT  K+ L   S+
Sbjct: 445 IDGDKI-------NGVSIKLGIAQDDAWTKACKFVLTCCKFLLAHASN 485


>UniRef50_Q55CC5 Cluster: Autophagy protein 6; n=2; Dictyostelium
            discoideum|Rep: Autophagy protein 6 - Dictyostelium
            discoideum AX4
          Length = 1368

 Score =  132 bits (319), Expect = 2e-29
 Identities = 88/252 (34%), Positives = 124/252 (49%), Gaps = 28/252 (11%)

Query: 200  EQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHI-------- 251
            E+  ++     Y ++    + + + Y  Q+   + QLE++ + ++ K TF I        
Sbjct: 1110 EEKTHYDLVNNYYQEYFDLKQEDEIYTNQINAIRDQLERVSQIDINKITFKIELPNTGVN 1169

Query: 252  --------SDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRY 303
                    S +     IN FRLG L    VDW EIN+AWG+T LLL  LA ++ FNFQ Y
Sbjct: 1170 GGIVGYNESSNTTISSINGFRLGTLSNLKVDWEEINSAWGETSLLLYVLASQLEFNFQNY 1229

Query: 304  KLVPYGNHSYIEVLEDQKVLPLYGSGGFR----FLW----DTKFDAAMVAFLDCLQQFKE 355
            KL+P  + S I+   D+    LYG    +    FLW    D +FD+ M AFL C+     
Sbjct: 1230 KLIPMSSKSIIQSKNDKMSYTLYGGDNIQFSRSFLWFGASDQRFDSGMEAFLSCVNDIAT 1289

Query: 356  QVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWI 415
             V+         YRI K KI D+       SIKI  NSE +WT AL++ML+NLK  L  +
Sbjct: 1290 FVQSKKPSINFNYRISKDKIGDS---NRLLSIKIAGNSELNWTMALRFMLSNLKKILDNL 1346

Query: 416  SSQFCEDKSEPQ 427
             S   E K + Q
Sbjct: 1347 DS-IVESKQKQQ 1357


>UniRef50_Q4A1C3 Cluster: Beclin 1; n=3; Saccharomycetaceae|Rep:
           Beclin 1 - Kluyveromyces waltii (Yeast)
          Length = 457

 Score =  127 bits (306), Expect = 6e-28
 Identities = 122/454 (26%), Positives = 189/454 (41%), Gaps = 58/454 (12%)

Query: 12  CQRCLQPLKLDDSLNNLG------------EHTIADLTL---QIRRNNE----ADLDLQS 52
           CQ C  PL+LD SL +L             E T   L L   ++RR N     ++L+LQ 
Sbjct: 9   CQNCQVPLELDTSLMDLSLAQRNLLMNSTIEPTTQQLQLPPDRLRRLNSIEKVSNLNLQP 68

Query: 53  S---SLDHYVPPFRMSESGN------GANGFMVISDGWETTSLGHQLHVKATLFDLLSNN 103
           S   +L+ YV  F   +SG+               D      L  +++    +F+L+S+ 
Sbjct: 69  SVLNNLESYV--FLNDDSGSLQHTRLDGESSEEADDDNAPKILSSRVNTLTNIFNLVSSK 126

Query: 104 SYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXWK 163
           S +D+P+C +C D L+  +    ++   E                               
Sbjct: 127 SNIDYPVCQDCLDALIHKLKGDYEEALKERDTYTEFLDRLNKQQGLEQSKPQNVNGAL-- 184

Query: 164 QEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRK-------DLM 216
            E+ R              ++             + E+ +   E ++ RK       DL 
Sbjct: 185 -EEERAAALKEQEELLQELISLERTEAELDSTIEELEEGIRQEELSQLRKIEAENARDLE 243

Query: 217 TTE--DQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVD 274
             E   +++  + Q   T + L+KL+KTN+F  TF IS  G FG IN  RLG L    V 
Sbjct: 244 ELEFSKELQSLKNQYETTLNGLDKLRKTNIFNETFRISHDGPFGTINELRLGGLDEIAVP 303

Query: 275 WSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVL----EDQKVLPLYGSGG 330
           W EINAA GQ VLLL+++  ++ F    Y L+P G++S IE      ++      + +G 
Sbjct: 304 WQEINAALGQVVLLLATICARLKFRLDGYILMPMGSYSKIERFDSNTQEWHAYDAFNNGS 363

Query: 331 FR----FLWDTKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYS 386
           FR    F  +T FD AMV+ L+ + Q    +  G      P   D+ ++  T        
Sbjct: 364 FRLGRFFHKETSFDRAMVSILEIISQITSHLSEGQ-----PTDTDEIELPYTMQGDKING 418

Query: 387 IKIQF---NSEEHWTKALKYMLTNLKWALTWISS 417
           + I+    N    WT A K++LTN KW L + SS
Sbjct: 419 VPIKLCGNNPGPDWTVACKFLLTNSKWLLAFSSS 452


>UniRef50_Q0UVG4 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 461

 Score =  122 bits (294), Expect = 2e-26
 Identities = 70/248 (28%), Positives = 116/248 (46%), Gaps = 10/248 (4%)

Query: 68  GNGANGFMVISDGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDNQLK 127
           G+G  G   ++DG ETT+          +F++LS+ S +DHP+C ECT+ L++ +  +L 
Sbjct: 145 GSGTVGGTSMADGLETTN---------RMFEILSSRSDIDHPICIECTELLVDGLQQRLG 195

Query: 128 QTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXWKQEQSRXXXXXXXXXXXXRA-MNXX 186
               E                               ++               +A ++  
Sbjct: 196 VATRERDAYVDYLRRANTDVPSAEEVKAADTALKTAKKTEAAAISNLEKLESEKAELDAQ 255

Query: 187 XXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFK 246
                     LD+E++ +W++   +   L   +++      + A+    L +L++ +V+ 
Sbjct: 256 LAALEAEARQLDQEENGFWKDRNAFNSTLTEFQNERDALTTRHAHDAQVLNQLQRRSVYN 315

Query: 247 ATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLV 306
            TF+I+    F  IN  RLGRLPT  VDW EINAAWGQT LLL++LA ++ + FQ Y+L 
Sbjct: 316 DTFNITHDNHFATINGLRLGRLPTPYVDWPEINAAWGQTCLLLATLAERLGYKFQGYELH 375

Query: 307 PYGNHSYI 314
           P G+ S I
Sbjct: 376 PMGSTSTI 383


>UniRef50_Q6CLQ7 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome F of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome F of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 461

 Score =  121 bits (291), Expect = 4e-26
 Identities = 91/357 (25%), Positives = 158/357 (44%), Gaps = 23/357 (6%)

Query: 85  SLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELM----DNQLKQTEAEWXXXXXXX 140
           +L  +++    +F++LS+ + VD+P+C  C DTLLE +    + +LK+ +          
Sbjct: 113 TLSSRINALGNIFNILSSKNNVDYPVCQGCCDTLLEKLKEEYNQELKKRDTYHDFMKRIQ 172

Query: 141 XXXXXXXXXXXXXXXXXXXXXWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKE 200
                                 K+E+ +              +                +
Sbjct: 173 EHKNVNGINIGDNRALEELSSLKKEKEQLLRELQRLEDEDEKLQKETILLQEELAKKKDQ 232

Query: 201 QDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGII 260
             V  ++      + +T    ++  + Q   T + ++KL+K N++  TF IS  G FG I
Sbjct: 233 YIVRLQKQNIQELEQLTFIKDVQSLKNQRVVTLNHIDKLRKLNIYNETFRISHDGPFGTI 292

Query: 261 NNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLE-- 318
           N+ +LG +P A V WSEIN+A GQ VLLLS +A K++ +F  YKL+P G+ S IE  +  
Sbjct: 293 NDLKLGSVPNASVPWSEINSALGQVVLLLSLIAEKLSVSFTDYKLIPMGSTSSIEKFDPK 352

Query: 319 -DQKVLPLYGSG-----GFRFLWDTKFDAAMVAFLDCLQQFKEQVEMGN---TGFCLPYR 369
            +Q  +    SG     G  F  ++  D A+   L+ +     +V   +       LPY 
Sbjct: 353 TNQWFVHKAFSGDEFSFGSLFHKESAIDKALTCILEIISLLSAKVSSDSQDPASIELPYE 412

Query: 370 IDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWISSQFCEDKSEP 426
           I   KI       +  +  ++      WT + K++LTN+KW L + ++    DK++P
Sbjct: 413 ILGDKINGLTILLNGATPSLE------WTTSCKFLLTNVKWLLAFSTAHI--DKNKP 461


>UniRef50_Q1E5P9 Cluster: Putative uncharacterized protein; n=1;
            Coccidioides immitis|Rep: Putative uncharacterized
            protein - Coccidioides immitis
          Length = 1119

 Score =  121 bits (291), Expect = 4e-26
 Identities = 73/189 (38%), Positives = 104/189 (55%), Gaps = 24/189 (12%)

Query: 197  LDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQ 256
            LD++++ +W + T +   L    +       +  +   QLE+L++TNV+  TF I   G 
Sbjct: 841  LDRDEEQFWTDQTTFGLTLGGFLNDRDTLNVKFDHDSRQLERLQRTNVYNDTFCIGHDGY 900

Query: 257  FGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEV 316
            FG IN  RLGRL   PV+W+E+NAAWGQTVLLLS++A K  F F+ Y+L P G+ S IE 
Sbjct: 901  FGTINGLRLGRLGNPPVEWAEVNAAWGQTVLLLSTIANKFGFQFEGYRLRPMGSVSRIEK 960

Query: 317  LE------------DQKVLP------LYGSGG--FRFLW-DTKFDAAMVAFLDCLQQ--- 352
            +E            D  + P      L+ SG       W   +FDA MVAFL+CL+Q   
Sbjct: 961  VEQSQREPNFRTGRDDNLSPIITSLDLFSSGDLPLNLPWLHRRFDAGMVAFLECLRQLGV 1020

Query: 353  FKEQVEMGN 361
            + E+V + N
Sbjct: 1021 YLEKVPLSN 1029



 Score = 38.7 bits (86), Expect = 0.29
 Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 8/45 (17%)

Query: 363  GFCLPYRIDKGKIEDTASPPHAYSIKIQFN-SEEHWTKALKYMLT 406
            G  LPY I K +I DT       SI++ FN ++E WT+A KYMLT
Sbjct: 1063 GMKLPYEIQKDRIGDT-------SIRLGFNQTDESWTRACKYMLT 1100


>UniRef50_Q22592 Cluster: Beclin (Human autophagy) homolog protein
           1; n=2; Caenorhabditis|Rep: Beclin (Human autophagy)
           homolog protein 1 - Caenorhabditis elegans
          Length = 375

 Score =  120 bits (290), Expect = 6e-26
 Identities = 85/320 (26%), Positives = 132/320 (41%), Gaps = 8/320 (2%)

Query: 96  LFDLLSNNSYV-DHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXX 154
           L  L+S+  +  D P+C++C+D L   MD Q+   + E                      
Sbjct: 49  LMKLISDAQFPSDAPVCNDCSDALRNEMDAQVATLDDEIKTYQTYINYLKENHPTTSIPD 108

Query: 155 XXXXXXXWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKD 214
                     E+                ++              ++    W++Y    + 
Sbjct: 109 LKAKLQNVSDEEKELEQQLKKLLAEEEQLDLDLQTKRRTAEAASEKSGELWKKYRDNLRQ 168

Query: 215 LMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVD 274
           +   +D++   E +  Y + Q  KL  TNV    FHI   G  G IN FRLG L  APV+
Sbjct: 169 VFEDQDELHSLEAERQYAEVQHRKLTDTNVLDLCFHIWVDGIVGEINGFRLGYLKDAPVE 228

Query: 275 WSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLE---DQKVLPLYGSGGF 331
           ++EINAA GQ VLLL  L  +I         V  G+HSYI++     D +   LYG  G 
Sbjct: 229 FTEINAALGQIVLLLEILLERIGVQHHELMPVAMGSHSYIKLRRNGIDMETYALYGQ-GT 287

Query: 332 RFLWDTKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQF 391
                +  D  +  FL  L+   ++++  N  F  PY+I    + D       Y+  +  
Sbjct: 288 PLSGSSGIDPGIRRFLQLLEFLLKELKDRNKNFKPPYQIHADSLVDNGV---KYNAVMTL 344

Query: 392 NSEEHWTKALKYMLTNLKWA 411
           N++  WT+A+  MLT+LK A
Sbjct: 345 NTDVRWTRAMALMLTDLKAA 364


>UniRef50_Q0DTB6 Cluster: Os03g0258500 protein; n=1; Oryza sativa
           (japonica cultivar-group)|Rep: Os03g0258500 protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 528

 Score =  119 bits (286), Expect = 2e-25
 Identities = 67/186 (36%), Positives = 99/186 (53%), Gaps = 12/186 (6%)

Query: 201 QDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGII 260
           ++ YW E+  ++  L + +++ +    ++  +Q  LE LK+ NV    F+IS  G  G I
Sbjct: 171 EERYWHEFNSFQFQLTSHQEEREAILAKIEVSQVHLELLKRRNVLNDAFYISHDGVIGTI 230

Query: 261 NNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQ-RYKLVPYGNHSYIEVLED 319
           NNFRLGRLP   V+W EINAAWGQ  LLL ++A+     F+ R K+ P G+++ +  +  
Sbjct: 231 NNFRLGRLPNVQVEWDEINAAWGQAALLLHTMAQYFTPKFEYRIKIHPMGSYARVTDIHK 290

Query: 320 ---QKVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQFKE---QVEMGNT-----GFCLPY 368
              +  + L   G     W T+FD AM  FL CLQ F E    ++  N         LPY
Sbjct: 291 NTYELYIMLTRFGPVDLFWSTRFDKAMTWFLTCLQDFAEFAISLDKENNVPPEKSLKLPY 350

Query: 369 RIDKGK 374
           +ID  K
Sbjct: 351 KIDGDK 356


>UniRef50_Q4P6J8 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 535

 Score =  116 bits (278), Expect = 2e-24
 Identities = 76/251 (30%), Positives = 119/251 (47%), Gaps = 29/251 (11%)

Query: 197 LDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQ 256
           L +E++ +W +Y+++   L   E+        +A+ +  L +L+ TNV+   F I  SG 
Sbjct: 255 LQQEEERFWSQYSQHSLTLSRLEEDKASLAMAVAHDRELLLRLQSTNVYTDAFCIGHSGG 314

Query: 257 FGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEV 316
              IN  RLGRLP   V+W+EINAAWGQT LLL  +ARK+   F+ Y+L+P G+ S +  
Sbjct: 315 IATINGLRLGRLPGQSVEWNEINAAWGQTALLLDVVARKLGVAFRGYRLIPKGSFSVVYR 374

Query: 317 LEDQKVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQ------------------FKEQVE 358
            ED +      +     L+    DA      +   +                     + +
Sbjct: 375 YEDARSQHYSSASSTSTLFAASNDATETEGEETAGEKTVYELYGSSDWQIGRLLQSRRFD 434

Query: 359 MGNTGF--CLPYRID-KGKIEDTASPPHAY--------SIKIQFNSEEHWTKALKYMLTN 407
              TGF  CL   ++     + T   PHA         SI++QF S+E WT+AL+++L N
Sbjct: 435 HAQTGFLACLKQVVEFAASADPTFQAPHAINKDKIGEASIRLQFGSDETWTRALRHVLVN 494

Query: 408 LKWALTWISSQ 418
               L W+S +
Sbjct: 495 CNRVLMWVSER 505



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 15/32 (46%), Positives = 25/32 (78%)

Query: 101 SNNSYVDHPLCDECTDTLLELMDNQLKQTEAE 132
           ++++ +DHPLC  CTDTLLE+MD Q+ +  ++
Sbjct: 126 NSSTVIDHPLCKACTDTLLEIMDTQMSEVRSQ 157


>UniRef50_P87117 Cluster: Uncharacterized protein C20G8.10c; n=2;
           Schizosaccharomyces pombe|Rep: Uncharacterized protein
           C20G8.10c - Schizosaccharomyces pombe (Fission yeast)
          Length = 499

 Score =  109 bits (263), Expect = 1e-22
 Identities = 68/234 (29%), Positives = 102/234 (43%), Gaps = 9/234 (3%)

Query: 89  QLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDNQLK--QTEAEWXXXXXXXXXXXXX 146
           ++ +   +FDLLS+ + VDHPLC EC + L E M   L+  + E +              
Sbjct: 121 KIEIYNRIFDLLSSKTKVDHPLCVECAELLTEEMSKTLRALKEEKKMYFNYDNFLSSQTV 180

Query: 147 XXXXXXXXXXXXXXXWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWR 206
                           KQ   +            +                 +EQ+ Y  
Sbjct: 181 HEENTAALDSEIDELMKQINEKEEKIEEISDETDKLQKLLRELDEEKEKVYAEEQEFY-N 239

Query: 207 EYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISD------SGQFGII 260
              +++   ++ E Q      +  +   +LEKL+K NVF   F+IS        G    I
Sbjct: 240 NLNQFQIKKLSLERQYDCANLEFEHNSRKLEKLQKMNVFSDIFYISHYSEPNGEGSIATI 299

Query: 261 NNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYI 314
           N  RLGRLP+  V+W+EINAAWG TVLLL  L  K++F+   Y+L P+G+ S+I
Sbjct: 300 NGLRLGRLPSQKVNWAEINAAWGMTVLLLDVLTEKLDFHSSSYQLKPFGSQSFI 353



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 44/132 (33%), Positives = 72/132 (54%), Gaps = 15/132 (11%)

Query: 295 KINFNFQRYKLVPYGNHSYIEVLE----DQKVLP----LYGSGGFRFLWDTKFDAAMVAF 346
           K++F+   Y+L P+G+ S+I   +      +V P    L+ SG  +   + +FD  MVAF
Sbjct: 369 KLDFHSSSYQLKPFGSQSFIIRFDRDPNGNQVKPTKLDLFSSGELKIFMNRRFDQGMVAF 428

Query: 347 LDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLT 406
           LD L QF +          LPY I+  +I           I++ FN +E+WT+ALK++LT
Sbjct: 429 LDYLHQFGDFCAAKTPSAVLPYAIENDRIGGKC-------IRLAFNQDENWTRALKFVLT 481

Query: 407 NLKWALTWISSQ 418
           ++K+   ++SSQ
Sbjct: 482 DIKFLEAYVSSQ 493


>UniRef50_A5DIV5 Cluster: Autophagy-related protein 6; n=4;
           Saccharomycetaceae|Rep: Autophagy-related protein 6 -
           Pichia guilliermondii (Yeast) (Candida guilliermondii)
          Length = 461

 Score =  100 bits (240), Expect = 6e-20
 Identities = 74/212 (34%), Positives = 107/212 (50%), Gaps = 19/212 (8%)

Query: 215 LMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVD 274
           L    DQ+   + +     ++L+ L+  N++   F I+   QFG IN FRLG      V 
Sbjct: 260 LQRKADQLAQEKARYRVVLNRLDHLRNLNMYTKFFDIAADDQFGKINGFRLGY----KVP 315

Query: 275 WSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVL-----EDQKVLPLYGSG 329
           W E+N A GQ VLL   L ++++   Q YKLVP G+ S I  L     + + VL LY S 
Sbjct: 316 WLEVNCALGQVVLLAVFLCKRLDVRLQSYKLVPMGSRSQIVKLSSDHDKSKTVLNLYLSN 375

Query: 330 GFRF--LWD-TKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYS 386
                 L++  K D +M+A LD L Q +  V   ++   LPY I   K  D        S
Sbjct: 376 ELSLGKLFNFNKLDVSMIALLDVLSQIEATVLALDSEIELPYTISPKK--DVIG---GKS 430

Query: 387 IKIQFNSEEHWTKALKYMLTNLKWALTWISSQ 418
           I++  NS+  WT + K++L N KW LT+ SS+
Sbjct: 431 IRVTSNSD--WTFSCKFLLVNFKWILTYASSR 460



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 17/44 (38%), Positives = 27/44 (61%)

Query: 89  QLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDNQLKQTEAE 132
           ++H    +FD+LSN   V+HP+CDEC + L+E    +  Q + E
Sbjct: 125 RIHTLEKIFDILSNKGEVNHPMCDECAELLIENYKLKFDQNQRE 168


>UniRef50_Q02948 Cluster: Vacuolar protein sorting-associated
           protein 30; n=5; Saccharomyces|Rep: Vacuolar protein
           sorting-associated protein 30 - Saccharomyces cerevisiae
           (Baker's yeast)
          Length = 557

 Score =   99 bits (238), Expect = 1e-19
 Identities = 90/380 (23%), Positives = 161/380 (42%), Gaps = 47/380 (12%)

Query: 85  SLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELM----DNQLKQ--TEAEWXXXXX 138
           +L  Q++    +F++LS+ + +D P+C +C + L+  +    D+ +K+  T A++     
Sbjct: 156 TLSTQVNAMTNVFNILSSQTNIDFPICQDCCNILINRLKSEYDDAIKERDTYAQFLSKLE 215

Query: 139 XXXXXXXXXXXXXXXXXXXXXXX-WKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXL 197
                                    K+E+ R              ++            L
Sbjct: 216 SQNKEISESNKEKQYSHNLSEKENLKKEEERLLDQLLRLEMTDDDLDGELVRLQEKKVQL 275

Query: 198 DKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQF 257
           + E+     +      + +     ++  + Q   + +QL+KL+K N+F ATF IS SG F
Sbjct: 276 ENEKLQKLSDQNLMDLNNIQFNKNLQSLKLQYELSLNQLDKLRKINIFNATFKISHSGPF 335

Query: 258 GIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYG-------- 309
             IN  RLG +P + V W EINAA GQ +LLL+++ + +  N   Y+L P G        
Sbjct: 336 ATINGLRLGSIPESVVPWKEINAALGQLILLLATINKNLKINLVDYELQPMGSFSKIKKR 395

Query: 310 -------NHSYIEVLEDQKVLPLYGSGGFR----FLWDTKFDAAMVAFLDCLQQFKEQVE 358
                  N+S      D  +LP+Y    F     F  +TKFD ++   L+ + +   Q+ 
Sbjct: 396 MVNSVEYNNSTTNAPGDWLILPVYYDENFNLGRIFRKETKFDKSLETTLEIISEITRQLS 455

Query: 359 MGNTGF---CLPYRIDKGK------IEDTAS-----------PPHAYSIKIQFNSEE-HW 397
              + +    L    D+        +E++ S             +  S+K+  +S    W
Sbjct: 456 TIASSYSSQTLTTSQDESSMNNANDVENSTSILELPYIMNKDKINGLSVKLHGSSPNLEW 515

Query: 398 TKALKYMLTNLKWALTWISS 417
           T A+K++LTN+KW L + S+
Sbjct: 516 TTAMKFLLTNVKWLLAFSSN 535


>UniRef50_A7TQC4 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 487

 Score = 99.5 bits (237), Expect = 1e-19
 Identities = 71/214 (33%), Positives = 106/214 (49%), Gaps = 37/214 (17%)

Query: 234 SQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLA 293
           ++L+ L+K N++  TF IS  G FG IN  RLG     PV W EINAA GQ +LLL++++
Sbjct: 276 NRLDTLRKINIYNETFKISHEGPFGTINGLRLGGFDDVPVPWDEINAALGQVILLLATIS 335

Query: 294 RKINFNFQRYKLVPYGNHSYIEVL----EDQKVLPLYGSGGFR----FLWDTKFDAAMVA 345
            ++NF    Y+L P G+ S I       +D   L  Y    F+    F  +T FD ++  
Sbjct: 336 TRLNFKLDGYRLQPMGSFSKIAKFDNDTQDWIALEAYNDENFKVGRLFRRETNFDKSLEC 395

Query: 346 FLDCLQQF----------KEQVEMGNTG---------FCLPYRIDKGKIEDTASPPHAYS 386
            L  + Q           + Q+    +G           LPY + K KI +        S
Sbjct: 396 LLTIIHQLCVNLTNSNITESQLTTATSGNQEISSSQEIELPYEMIKDKINN-------IS 448

Query: 387 IKIQFNSEEH--WTKALKYMLTNLKWALTWISSQ 418
           +K+ F S+ +  WT A+K +LTN+KW L + SS+
Sbjct: 449 VKL-FGSKPNLEWTTAMKLVLTNIKWLLAYSSSR 481



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 53  SSLDHYVPPFRMSESGNGANGFMVISDGWETT-SLGHQLHVKATLFDLLSNNSYVDHPLC 111
           S+LD YV    M  SG+       +   + T+ +L   + V + LF++LS  S +D+P+C
Sbjct: 93  SALDPYVS--NMETSGDEQYSGTTVKQEYSTSKTLSTHVSVLSNLFNILSAKSSIDYPVC 150

Query: 112 DECTDTLLELMDNQLKQTEAE 132
            +C D L++ + +Q  +T  E
Sbjct: 151 QDCCDWLIQRLKSQYDETIKE 171


>UniRef50_A5E3I5 Cluster: Putative uncharacterized protein; n=3;
           Saccharomycetales|Rep: Putative uncharacterized protein
           - Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 536

 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 69/215 (32%), Positives = 112/215 (52%), Gaps = 28/215 (13%)

Query: 214 DLMTTEDQMKF-YECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAP 272
           D  T  DQ+K  Y+  L    + +++L+  N++K  F I+   ++G+IN  R+G      
Sbjct: 330 DKQTKLDQLKASYQLHL----NHIDELRNFNIYKLMFDINLDEKYGMINGLRIGY----K 381

Query: 273 VDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVL---ED----QKVLPL 325
           + W E+NAA GQ  LL++ + R+++   + YKLVP G+ S+I      ED    +K+L L
Sbjct: 382 IVWPEVNAALGQISLLVAFILRRLHLKLEAYKLVPMGSQSHIVKFTKHEDGSRSKKILNL 441

Query: 326 YGSGGF---RFLWDTKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPP 382
           Y S  F   R     K D +++A L+ L     ++   +T   LPY+I    I       
Sbjct: 442 YSSDEFTLGRLFNFNKMDVSLIALLEILSIISIKLRELDTDIELPYKIKNDSI------- 494

Query: 383 HAYSIKIQFNSEEHWTKALKYMLTNLKWALTWISS 417
              SI++  NSE  WT++ K +LTNL W L ++ +
Sbjct: 495 GGKSIRVTSNSE--WTQSCKLLLTNLNWMLIFVQA 527


>UniRef50_Q4A1C4 Cluster: Beclin 1; n=1; Clavispora lusitaniae|Rep:
           Beclin 1 - Clavispora lusitaniae (Candida lusitaniae)
          Length = 473

 Score = 93.5 bits (222), Expect = 1e-17
 Identities = 68/216 (31%), Positives = 114/216 (52%), Gaps = 29/216 (13%)

Query: 221 QMKFYECQLAYTQS--QLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEI 278
           Q KF + +  Y +    L++L+  N++   F IS   ++G IN FR+G      V W EI
Sbjct: 269 QNKFDKAKALYQKQLDYLDELRSLNIYTKLFSISFEDKWGRINGFRIGY----KVPWPEI 324

Query: 279 NAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYI--EVL-----------EDQKVLPL 325
           N A GQ V L++ L ++++ N   Y+L+P G+ SYI  +V+           ++  VLPL
Sbjct: 325 NVALGQIVQLITFLQKQLSVNLHSYELIPLGSKSYILKDVVGSNDSTGNSPSKNHSVLPL 384

Query: 326 YGSGGFRF--LWD-TKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPP 382
           + S  F    L++  K D +M+A LD + Q + ++   +    LPY+I   K +      
Sbjct: 385 FSSNEFTLGKLFNFNKLDVSMMALLDIVSQLELRLMNLDNELELPYKI-SAKHDSVGGK- 442

Query: 383 HAYSIKIQFNSEEHWTKALKYMLTNLKWALTWISSQ 418
              SI++  N +  WT+A +Y+L +L W L ++S+Q
Sbjct: 443 ---SIRVTSNGQ--WTEACRYLLIDLNWILAYVSAQ 473


>UniRef50_Q5KKK1 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 532

 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 60/172 (34%), Positives = 86/172 (50%), Gaps = 15/172 (8%)

Query: 197 LDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHI----- 251
           +++E++ +   ++     L      +      L  ++S L  L+ TNV+   FHI     
Sbjct: 255 VEQEENDFLTSHSALSIHLTQLASTLNTAHTSLLLSRSLLAHLESTNVYNDAFHIGHVPL 314

Query: 252 ----SDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVP 307
               S S   G IN  RLG  P   V+W EINAAWG   L L  +A K+   F+ YK+VP
Sbjct: 315 LPLASSSITVGTINGLRLGGRPV--VEWDEINAAWGLAALCLHRIAEKVGCVFETYKIVP 372

Query: 308 YGNHSYIEVLEDQK-VLPLYGSGGF---RFLWDTKFDAAMVAFLDCLQQFKE 355
            G++S +E L   K    LY S      R L + +F+ AMVAFL+CL+Q  E
Sbjct: 373 LGSYSRVEELPPSKSTYELYASSDMTPARLLQNRRFNHAMVAFLECLRQLLE 424



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 16/31 (51%), Positives = 20/31 (64%)

Query: 88  HQLHVKATLFDLLSNNSYVDHPLCDECTDTL 118
           H L + A L  +LS+N+ V HPLC ECT  L
Sbjct: 118 HDLDLSAQLHQILSSNTPVSHPLCTECTALL 148


>UniRef50_UPI00006CB2FF Cluster: hypothetical protein
           TTHERM_00455640; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00455640 - Tetrahymena
           thermophila SB210
          Length = 733

 Score = 87.0 bits (206), Expect = 8e-16
 Identities = 64/216 (29%), Positives = 96/216 (44%), Gaps = 7/216 (3%)

Query: 204 YWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLE-KLKKTNVFKATFHISDSGQFGIINN 262
           YW E   + K L T  ++ +  +    Y   +L  KL K N   + F I  S Q G+INN
Sbjct: 504 YWVEVNSFEKRLQTLLNKKQIADNLEQYYNDKLNNKLNKYNTINSVFFIEVSEQVGLINN 563

Query: 263 FRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPY-GNHSYIEVLEDQK 321
             +G+     ++W E NA  GQ +LL   L  K  +     K +   GN SYI   E  K
Sbjct: 564 LMIGKKLNEDINWDETNAGLGQVILLFLYLMNKFGYQSSYIKDIQVCGNESYI--CEANK 621

Query: 322 VLPLYGSGGFRFLWD-TKFDAAMVAFLDCLQQFKEQVEMGN-TGFCLPYRIDKGKIE-DT 378
              LY  G F    D  KF+ AM   LD    F + ++        LP++ID+     D 
Sbjct: 622 SEQLYLRGPFSNKGDEAKFNRAMKMILDEFSLFVDYLQQTYLQNIQLPFKIDQSNSSIDG 681

Query: 379 ASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTW 414
                  +   Q+   ++WT+A K +L N K+ +++
Sbjct: 682 LLLTTQTAANAQYKGLDNWTQAFKKLLINFKFLISF 717


>UniRef50_A7TB90 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 260

 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 37/80 (46%), Positives = 57/80 (71%), Gaps = 3/80 (3%)

Query: 197 LDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKAT---FHISD 253
           L++ +  Y+ EY +Y+++L+  ED+ +  + Q+ Y Q+QL+KLKKTNVF +T   + +  
Sbjct: 46  LEEAEKAYYTEYCEYQRELLDFEDEKQSVDNQMMYAQAQLDKLKKTNVFNSTGIPYMVRH 105

Query: 254 SGQFGIINNFRLGRLPTAPV 273
           +G FG INNFRLGRLP+ PV
Sbjct: 106 NGHFGTINNFRLGRLPSVPV 125


>UniRef50_Q6FP39 Cluster: Candida glabrata strain CBS138 chromosome
           J complete sequence; n=1; Candida glabrata|Rep: Candida
           glabrata strain CBS138 chromosome J complete sequence -
           Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 512

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 49/147 (33%), Positives = 75/147 (51%), Gaps = 8/147 (5%)

Query: 214 DLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPV 273
           D M   + +   + Q     ++L++L+KTN++  +F IS  G F  I   +LG      V
Sbjct: 266 DKMKLLNDISSLQYQYETELNKLDQLRKTNIYNESFRISHQGPFATICGLKLGSYEDHKV 325

Query: 274 DWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHS----YIEVLEDQKVLPLYGSG 329
            +SEINAA GQ VLLL +++  +N     Y+L P G+ S    ++   ED +   LY S 
Sbjct: 326 SYSEINAALGQLVLLLMTISSSLNIKISGYRLQPIGSTSKVSKFLADKEDWETYELYFSS 385

Query: 330 GFR----FLWDTKFDAAMVAFLDCLQQ 352
            F     F  +T FD  M + LD ++Q
Sbjct: 386 NFSLEKIFKRETDFDKGMESLLDIVKQ 412



 Score = 33.9 bits (74), Expect = 8.2
 Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 10/55 (18%)

Query: 366 LPYRIDKGKIEDTASPPHAYSIKIQFNSEEH--WTKALKYMLTNLKWALTWISSQ 418
           LPY ID  +I       +  S+K+ + +E +  WT A+K++LT+ KW L + SS+
Sbjct: 462 LPYMIDGDRI-------NGISVKL-YGAEPNLEWTTAMKFLLTDAKWLLVFCSSK 508


>UniRef50_Q4A1C1 Cluster: Beclin 1; n=1; Saccharomyces castelli|Rep:
           Beclin 1 - Saccharomyces castelli
          Length = 497

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 40/135 (29%), Positives = 67/135 (49%), Gaps = 8/135 (5%)

Query: 234 SQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLA 293
           + L++L+K N++  TF I+ +G F  IN  R+G      V W EINA  G  VLLL+++ 
Sbjct: 267 NDLDQLRKINIYDETFKIAHNGPFATINGLRIGGFDDLKVSWKEINAGIGHVVLLLATIV 326

Query: 294 RKINFNFQRYKLVPYGNHS----YIEVLEDQKVLPLYGSGGFR----FLWDTKFDAAMVA 345
            ++N +   Y+L P G+ S    Y    +D      +    F+       +T+ D A+ +
Sbjct: 327 TQLNCSINGYRLRPMGSFSKILKYNTDSQDWITFEAFHDEKFKIGKLLHKETELDRALES 386

Query: 346 FLDCLQQFKEQVEMG 360
            L+ +QQ    +  G
Sbjct: 387 LLEIIQQMAISISTG 401



 Score = 37.9 bits (84), Expect = 0.50
 Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 3/82 (3%)

Query: 46  ADLDLQSSSLDHYV--PPFRMSESGNGANGFMVISDGWETTSLGHQLHVKATLFDLLSNN 103
           + LDL+ ++ + Y+     ++             S G   T L  Q  V + +F++LS  
Sbjct: 68  SQLDLKPNNQESYIFLKQSKLPTESQDQEDLQPSSQGVSKT-LSTQTSVLSNIFNILSGR 126

Query: 104 SYVDHPLCDECTDTLLELMDNQ 125
           + +D+P+C +C + L++ + NQ
Sbjct: 127 NKIDYPVCQDCCNLLIQDLKNQ 148



 Score = 37.5 bits (83), Expect = 0.67
 Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 10/55 (18%)

Query: 366 LPYRIDKGKIEDTASPPHAYSIKIQFNSEEH--WTKALKYMLTNLKWALTWISSQ 418
           LPY + K KI       +  S+K+ F ++ +  WT A+K++LTN+KW L + SSQ
Sbjct: 444 LPYIMHKDKI-------NGISVKL-FGADPNLEWTTAMKFLLTNVKWLLAYSSSQ 490


>UniRef50_A0DRK9 Cluster: Chromosome undetermined scaffold_60, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_60,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 341

 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 55/236 (23%), Positives = 109/236 (46%), Gaps = 20/236 (8%)

Query: 198 DKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQF 257
           +  +D  W    K+ + L +  +  +  + +L+   ++L++L K +V    F IS   + 
Sbjct: 108 EHNEDNLWEHINKFTRKLYSLFESNQIADNKLSQLNNELDRLSKLDVLNDLFKISVQDEV 167

Query: 258 GIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPY-GNHSYIEV 316
             IN  ++G+    PVDW +I+A  G   LLL  L +K  + +Q+ + +   G+ S I++
Sbjct: 168 ATINGLQIGKKGEQPVDWDDISAGVGHLTLLLVYLMKKFMYTYQKIESIELNGSFSKIKI 227

Query: 317 LED------QKVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQFKEQVEMGN------TGF 364
            ++       K L LY +       + +F  A +      QQF + ++ G+         
Sbjct: 228 KDEYQNTLCTKTLNLYLNNKTSQKDEEEFSDAFLQLYFEFQQFCKYLQDGDILRKRKINL 287

Query: 365 CLPYRIDKGKIEDTASPPHAYSIKIQFNSE-EHWTKALKYMLTNLKWALTWISSQF 419
            LP+ ++   +++        S+K     + + WT ++K  L N+K AL   ++QF
Sbjct: 288 NLPFTMNGMSVDN-----KILSLKQPAAQKWQEWTNSVKKFLANVK-ALIVANAQF 337


>UniRef50_Q7YY64 Cluster: Beclin1-like protein, possible; n=3;
           Cryptosporidium|Rep: Beclin1-like protein, possible -
           Cryptosporidium parvum
          Length = 420

 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 50/203 (24%), Positives = 92/203 (45%), Gaps = 13/203 (6%)

Query: 212 RKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTA 271
           + +L+  E + +  +  L + +  LE+LK+++    +F+I        IN  R       
Sbjct: 214 KHELIQYELKREGMKNHLDFLRGYLERLKRSDFLNLSFYIQVIEGGACINGLRPALFEAD 273

Query: 272 PVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLEDQKVLPLYGSGGF 331
             +W+E+NAA G + +LL ++  +       Y   P G++S I+  E   + PL+G+   
Sbjct: 274 FDNWNEVNAALGVSAMLLYTILERHKLPLSIY---PNGSYSTIKDSE-SSIWPLHGNTLC 329

Query: 332 RFLWD--TKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKI 389
              ++  T FD  +++F+  +      +    T   LPY +D+             S+ +
Sbjct: 330 NSDYNECTNFDKGILSFVFLIDTVYNIIP--GTNETLPYSVDQRN-----GTIGGISLNL 382

Query: 390 QFNSEEHWTKALKYMLTNLKWAL 412
            FN  E W +A+   L NLKW L
Sbjct: 383 LFNERESWNRAMSMNLINLKWLL 405


>UniRef50_A2WTT4 Cluster: Putative uncharacterized protein; n=3;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. indica (Rice)
          Length = 604

 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 47/133 (35%), Positives = 63/133 (47%), Gaps = 21/133 (15%)

Query: 290 SSLAR-KINFNFQRYKLVPYGNHSYIEVLEDQK-----VLPLYGSGGFRFLWDTKFDAAM 343
           S L R K+   F RY++  +   SY  V +  K      + L   G     W T+FD AM
Sbjct: 187 SKLGRTKVPELFSRYRIKIHPMGSYPRVTDIHKNTYELYIMLTRFGPVNLFWSTRFDKAM 246

Query: 344 VAFLDCLQQFKE---QVEMGNT-----GFCLPYRIDKGKIEDTASPPHAYSIKIQFNSEE 395
             FL CLQ F E    ++  N         LPY+ID  K+        +++I + FN  E
Sbjct: 247 TWFLTCLQDFAEFAISLDKENNVPPEKSLKLPYKIDGDKVG-------SHTIFLSFNKVE 299

Query: 396 HWTKALKYMLTNL 408
           +WTKALKY L NL
Sbjct: 300 NWTKALKYTLCNL 312


>UniRef50_Q5AFW0 Cluster: Putative uncharacterized protein VPS30;
           n=2; Candida albicans|Rep: Putative uncharacterized
           protein VPS30 - Candida albicans (Yeast)
          Length = 409

 Score = 57.2 bits (132), Expect = 8e-07
 Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 8/100 (8%)

Query: 210 KYRKDLMTTEDQMKFYECQLAYTQS--QLEKLKKTNVFKATFHISDSGQ--FGIINNFRL 265
           K +  L   E   K  + + AY      ++KL+  N++   FHIS   Q  F  IN FRL
Sbjct: 298 KNKLQLELNEKNKKLEQSKAAYDVQLDHIDKLRNLNIYTRIFHISCDSQDKFATINGFRL 357

Query: 266 GRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKL 305
           G      + W EINAA GQ VLLL  L +++  + +++K+
Sbjct: 358 GH----KIIWPEINAALGQIVLLLVFLIKRLIISIEKFKI 393



 Score = 36.3 bits (80), Expect = 1.5
 Identities = 14/37 (37%), Positives = 23/37 (62%)

Query: 96  LFDLLSNNSYVDHPLCDECTDTLLELMDNQLKQTEAE 132
           +F +LSNN  +DHPL ++C   L+E    +  Q++ E
Sbjct: 161 IFAILSNNQEIDHPLSEDCAKLLIENYQLKFDQSQKE 197


>UniRef50_A2EVY0 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 364

 Score = 43.6 bits (98), Expect = 0.010
 Identities = 50/185 (27%), Positives = 76/185 (41%), Gaps = 15/185 (8%)

Query: 229 LAYTQSQLEKLKKTNVFKA--TFHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTV 286
           L   Q+  E LK  N F A  TF IS +G +G IN  RLG     PV   EIN+     +
Sbjct: 174 LMLRQNPNENLK-VNTFVACTTFVISSNGHYGTINELRLGTQTPTPVPLEEINSG---LM 229

Query: 287 LLLSSLARKINFNFQRYKLVPYGNHSYIEVLEDQKVLPLYGSGGFRFLWDTKFDAAMVAF 346
           LL   L   ++        +  G     ++ + +  L  +     + +   +F+ AM   
Sbjct: 230 LLCQILNYYLSITKAYIFEIHLGPEMTFKIHDHEYTLTAFDLKHKKSV--KRFNEAMDII 287

Query: 347 LDCLQQFKEQVEMGNTGFCLPYRIDKGKIEDTASPPHAYSIKIQFNSEEHWTKALKYMLT 406
           +     F       ++G   P  + K K +      + Y +K      E WT A+KY+L 
Sbjct: 288 MSV---FSHVFVFFDSGQPRPPFLIKPKDKTIGGESYEYELK----HPEKWTLAMKYLLA 340

Query: 407 NLKWA 411
           NLK A
Sbjct: 341 NLKSA 345


>UniRef50_UPI0000F1E4DF Cluster: PREDICTED: hypothetical protein;
          n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
          Danio rerio
          Length = 87

 Score = 42.3 bits (95), Expect = 0.023
 Identities = 24/49 (48%), Positives = 28/49 (57%), Gaps = 3/49 (6%)

Query: 8  VSFSCQRCLQPLKLDDSLNNLGEHTIADLT---LQIRRNNEADLDLQSS 53
          VSF CQRC QPLKLD S N L   TI +LT   + +  N + D    SS
Sbjct: 13 VSFVCQRCNQPLKLDTSFNVLDRMTIHELTAPLVMVTANKQQDSGESSS 61


>UniRef50_UPI000049A39E Cluster: hypothetical protein 18.t00047;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 18.t00047 - Entamoeba histolytica HM-1:IMSS
          Length = 382

 Score = 36.3 bits (80), Expect = 1.5
 Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 7/120 (5%)

Query: 204 YWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNF 263
           YWR   K  KDL  + D+       +A  + +L+ ++K ++F + F + +S   G +   
Sbjct: 149 YWRINNKLLKDLQQSTDEQLELSNTIALLKDELQTIEKRSIFGSLFEV-ESFSDGSVT-- 205

Query: 264 RLGRLP-TAPVD-WSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLEDQK 321
            L  +P    +D  +E N A G+ VL +  + +KI         +P+ ++S I V   QK
Sbjct: 206 -LCGIPFKYSIDKVNEFNIAMGKLVLGIYLMGKKIIPKHSTIP-IPFDDYSQISVQIGQK 263


>UniRef50_A7F0B5 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 1063

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 10/108 (9%)

Query: 24  SLNNLGEHTIAD-LTLQIRRNNEADLDL--QSSSLDHYVPPFRMSESGNG---ANGFMVI 77
           S +NL      D L+ Q++  +EA++DL  QS     Y  P   S +GN    A GF+ +
Sbjct: 489 SKDNLAVSAAFDKLSSQVQAKDEAEIDLARQSGDFALYGNPLPSSSNGNAALYATGFLFL 548

Query: 78  S-DGWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDN 124
           S   W  TSL  Q+    + F    N S ++  L +  TD   EL  N
Sbjct: 549 SFMSWIITSL--QMCAPLSYFSQTDNGSILNR-LANVHTDVSTELKKN 593


>UniRef50_Q6YR34 Cluster: Isoleucyl-tRNA synthetase; n=4; Candidatus
           Phytoplasma|Rep: Isoleucyl-tRNA synthetase - Onion
           yellows phytoplasma
          Length = 900

 Score = 34.7 bits (76), Expect = 4.7
 Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 4/49 (8%)

Query: 80  GWETTSLGHQLHVKATLFDLLSNNSYVDHPLCDECTDTLLELMDNQLKQ 128
           GW+T    H L ++A +    S N++   PL D+C +  LE ++NQ  Q
Sbjct: 95  GWDT----HGLPIEAAVLKKTSKNAFTRKPLLDKCQEFALENVNNQKHQ 139


>UniRef50_Q6ZPK1 Cluster: MKIAA1686 protein; n=13; Euteleostomi|Rep:
           MKIAA1686 protein - Mus musculus (Mouse)
          Length = 1205

 Score = 34.3 bits (75), Expect = 6.2
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 205 WREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISD 253
           WREY K   D+  T DQM+    +L   QS+   +++  + K  + I D
Sbjct: 758 WREYDKLEYDVTVTRDQMQGQLDRLGEVQSESAGIQRAQIQKELWRIQD 806


>UniRef50_Q4XW84 Cluster: Cdc2-like protein kinase, putative; n=5;
           Plasmodium|Rep: Cdc2-like protein kinase, putative -
           Plasmodium chabaudi
          Length = 727

 Score = 34.3 bits (75), Expect = 6.2
 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)

Query: 213 KDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFK-ATFH-ISDSGQFGIINNFRLGRLPT 270
           K++M T +++ FY+    Y  S  + +KK N FK ++FH I     +  I   R+ R  +
Sbjct: 630 KNVMETNEEVSFYDDSTTYYTSPTKPIKKINKFKRSSFHSIIPEQSYEFIKGIRVKRNLS 689

Query: 271 APVDWSEIN 279
            P D+S  N
Sbjct: 690 IP-DFSSPN 697


>UniRef50_A2FQ97 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 384

 Score = 34.3 bits (75), Expect = 6.2
 Identities = 18/46 (39%), Positives = 26/46 (56%)

Query: 249 FHISDSGQFGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLAR 294
           FHIS +  +G IN  RLG+  +  V + EIN  +     L+SS+ R
Sbjct: 222 FHISYNRFYGTINTLRLGQNISREVPYEEINNGFTMLFHLISSMCR 267


>UniRef50_A6TJJ0 Cluster: Transposase IS66; n=1; Alkaliphilus
           metalliredigens QYMF|Rep: Transposase IS66 -
           Alkaliphilus metalliredigens QYMF
          Length = 533

 Score = 33.9 bits (74), Expect = 8.2
 Identities = 14/43 (32%), Positives = 29/43 (67%), Gaps = 1/43 (2%)

Query: 217 TTEDQMKFYECQLAYTQSQLEKLK-KTNVFKATFHISDSGQFG 258
           TTED++ F+E +LA  + ++E+L+ K   ++  F +S + ++G
Sbjct: 14  TTEDRLAFFENELAQKEQKIEELEAKVKFYEEQFRLSQAQKYG 56


>UniRef50_A1ZYM6 Cluster: Possible surface protein, responsible for
           cell interaction; contains cell adhesion domain and
           ChW-repeats; n=1; Microscilla marina ATCC 23134|Rep:
           Possible surface protein, responsible for cell
           interaction; contains cell adhesion domain and
           ChW-repeats - Microscilla marina ATCC 23134
          Length = 552

 Score = 33.9 bits (74), Expect = 8.2
 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 14/95 (14%)

Query: 39  QIRRNNEADLDLQSSSLDHYVPPFRMSESGNGANGFMVISDGWETTSLGHQLHVKATLFD 98
           Q++R N  D DL+S  L  Y+P  +M    N  N    I D W  T+L   L++      
Sbjct: 340 QLKRLNLDDNDLESLDLFKYMPQLQMLNLSN--NEIENIDDLWGLTNL-QWLNI------ 390

Query: 99  LLSNNSYVDHPLCDECTDTLLELM--DNQLKQTEA 131
              NN+ +++  C +  D LL LM  +N++K+ E+
Sbjct: 391 ---NNNQIENIDCLQLLDNLLFLMMSNNRIKEIES 422


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.319    0.133    0.411 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 425,088,448
Number of Sequences: 1657284
Number of extensions: 16144520
Number of successful extensions: 36952
Number of sequences better than 10.0: 50
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 36782
Number of HSP's gapped (non-prelim): 115
length of query: 427
length of database: 575,637,011
effective HSP length: 103
effective length of query: 324
effective length of database: 404,936,759
effective search space: 131199509916
effective search space used: 131199509916
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 74 (33.9 bits)

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