Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000092-TA|BGIBMGA000092-PA|IPR007243|Autophagy protein
Apg6, IPR013819|Lipoxygenase, C-terminal
(427 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC010276-1|AAH10276.1| 450|Homo sapiens beclin 1 (coiled-coil, ... 397 e-110
AF139131-1|AAD27650.1| 450|Homo sapiens beclin 1 protein. 397 e-110
AF077301-1|AAC68653.1| 450|Homo sapiens Bcl-2-interacting prote... 397 e-110
AK223411-1|BAD97131.1| 450|Homo sapiens beclin 1 variant protein. 392 e-108
L38932-1|AAB59573.1| 301|Homo sapiens protein ( Homo sapiens GT... 332 1e-90
>BC010276-1|AAH10276.1| 450|Homo sapiens beclin 1 (coiled-coil,
myosin-like BCL2 interacting protein) protein.
Length = 450
Score = 397 bits (977), Expect = e-110
Identities = 215/442 (48%), Positives = 264/442 (59%), Gaps = 26/442 (5%)
Query: 2 SDSKTFVSFSCQRCLQPLKLDDSLNNLGEHTIADLTLQIRRNNEA--------------- 46
++S VSF CQRC QPLKLD S L TI +LT + +A
Sbjct: 8 NNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEE 67
Query: 47 ---DLDLQSSSLDHYVPPFRMSESGNGANGFMVI---SDGWETTSLGHQLHVKATLFDLL 100
+ Q ++PP RM S AN F +I SDG +L +L V LFD++
Sbjct: 68 PFIETPRQDGVSRRFIPPARMM-STESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIM 126
Query: 101 SNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXX 160
S + VDHPLC+ECTDTLL+ +D QL TE E
Sbjct: 127 SGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKE 186
Query: 161 XWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTED 220
+E+ R + + LD+E+ Y REY+++++ + +D
Sbjct: 187 LALEEE-RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
Query: 221 QMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINA 280
++K E Q+ Y Q+QL+KLKKTNVF ATFHI SGQFG INNFRLGRLP+ PV+W+EINA
Sbjct: 246 ELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINA 305
Query: 281 AWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLEDQ-KVLPLYGSGGFRFLWDTKF 339
AWGQTVLLL +LA K+ FQRY+LVPYGNHSY+E L D+ K LPLY SGG RF WD KF
Sbjct: 306 AWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKF 365
Query: 340 DAAMVAFLDCLQQFKEQVEMGNTGFCLPYRID--KGKIEDTASPPHAYSIKIQFNSEEHW 397
D AMVAFLDC+QQFKE+VE G T FCLPYR+D KGKIEDT +YSIK QFNSEE W
Sbjct: 366 DHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQW 425
Query: 398 TKALKYMLTNLKWALTWISSQF 419
TKALK+MLTNLKW L W+SSQF
Sbjct: 426 TKALKFMLTNLKWGLAWVSSQF 447
>AF139131-1|AAD27650.1| 450|Homo sapiens beclin 1 protein.
Length = 450
Score = 397 bits (977), Expect = e-110
Identities = 215/442 (48%), Positives = 264/442 (59%), Gaps = 26/442 (5%)
Query: 2 SDSKTFVSFSCQRCLQPLKLDDSLNNLGEHTIADLTLQIRRNNEA--------------- 46
++S VSF CQRC QPLKLD S L TI +LT + +A
Sbjct: 8 NNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEE 67
Query: 47 ---DLDLQSSSLDHYVPPFRMSESGNGANGFMVI---SDGWETTSLGHQLHVKATLFDLL 100
+ Q ++PP RM S AN F +I SDG +L +L V LFD++
Sbjct: 68 PFIETPRQDGVSRRFIPPARMM-STESANSFTLIGEVSDGGTMENLSRRLKVTGDLFDIM 126
Query: 101 SNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXX 160
S + VDHPLC+ECTDTLL+ +D QL TE E
Sbjct: 127 SGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKE 186
Query: 161 XWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTED 220
+E+ R + + LD+E+ Y REY+++++ + +D
Sbjct: 187 LALEEE-RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
Query: 221 QMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINA 280
++K E Q+ Y Q+QL+KLKKTNVF ATFHI SGQFG INNFRLGRLP+ PV+W+EINA
Sbjct: 246 ELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINA 305
Query: 281 AWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLEDQ-KVLPLYGSGGFRFLWDTKF 339
AWGQTVLLL +LA K+ FQRY+LVPYGNHSY+E L D+ K LPLY SGG RF WD KF
Sbjct: 306 AWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKF 365
Query: 340 DAAMVAFLDCLQQFKEQVEMGNTGFCLPYRID--KGKIEDTASPPHAYSIKIQFNSEEHW 397
D AMVAFLDC+QQFKE+VE G T FCLPYR+D KGKIEDT +YSIK QFNSEE W
Sbjct: 366 DHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQW 425
Query: 398 TKALKYMLTNLKWALTWISSQF 419
TKALK+MLTNLKW L W+SSQF
Sbjct: 426 TKALKFMLTNLKWGLAWVSSQF 447
>AF077301-1|AAC68653.1| 450|Homo sapiens Bcl-2-interacting protein
beclin protein.
Length = 450
Score = 397 bits (977), Expect = e-110
Identities = 215/442 (48%), Positives = 264/442 (59%), Gaps = 26/442 (5%)
Query: 2 SDSKTFVSFSCQRCLQPLKLDDSLNNLGEHTIADLTLQIRRNNEA--------------- 46
++S VSF CQRC QPLKLD S L TI +LT + +A
Sbjct: 8 NNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEE 67
Query: 47 ---DLDLQSSSLDHYVPPFRMSESGNGANGFMVI---SDGWETTSLGHQLHVKATLFDLL 100
+ Q ++PP RM S AN F +I SDG +L +L V LFD++
Sbjct: 68 PFIETPRQDGVSRRFIPPARMM-STESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIM 126
Query: 101 SNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXX 160
S + VDHPLC+ECTDTLL+ +D QL TE E
Sbjct: 127 SGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKE 186
Query: 161 XWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTED 220
+E+ R + + LD+E+ Y REY+++++ + +D
Sbjct: 187 LALEEE-RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
Query: 221 QMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINA 280
++K E Q+ Y Q+QL+KLKKTNVF ATFHI SGQFG INNFRLGRLP+ PV+W+EINA
Sbjct: 246 ELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINA 305
Query: 281 AWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLEDQ-KVLPLYGSGGFRFLWDTKF 339
AWGQTVLLL +LA K+ FQRY+LVPYGNHSY+E L D+ K LPLY SGG RF WD KF
Sbjct: 306 AWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKF 365
Query: 340 DAAMVAFLDCLQQFKEQVEMGNTGFCLPYRID--KGKIEDTASPPHAYSIKIQFNSEEHW 397
D AMVAFLDC+QQFKE+VE G T FCLPYR+D KGKIEDT +YSIK QFNSEE W
Sbjct: 366 DHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQW 425
Query: 398 TKALKYMLTNLKWALTWISSQF 419
TKALK+MLTNLKW L W+SSQF
Sbjct: 426 TKALKFMLTNLKWGLAWVSSQF 447
>AK223411-1|BAD97131.1| 450|Homo sapiens beclin 1 variant protein.
Length = 450
Score = 392 bits (965), Expect = e-108
Identities = 214/442 (48%), Positives = 263/442 (59%), Gaps = 26/442 (5%)
Query: 2 SDSKTFVSFSCQRCLQPLKLDDSLNNLGEHTIADLTLQIRRNNEA--------------- 46
++S VSF CQRC QPLKLD S L TI +LT + +A
Sbjct: 8 NNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEE 67
Query: 47 ---DLDLQSSSLDHYVPPFRMSESGNGANGFMVI---SDGWETTSLGHQLHVKATLFDLL 100
+ Q ++PP RM S AN F +I SDG +L +L V LFD++
Sbjct: 68 PFIETPRQDGVSRRFIPPARMM-STESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIM 126
Query: 101 SNNSYVDHPLCDECTDTLLELMDNQLKQTEAEWXXXXXXXXXXXXXXXXXXXXXXXXXXX 160
S + VDHPL +ECTDTLL+ +D QL TE E
Sbjct: 127 SGQTDVDHPLREECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKE 186
Query: 161 XWKQEQSRXXXXXXXXXXXXRAMNXXXXXXXXXXXXLDKEQDVYWREYTKYRKDLMTTED 220
+E+ R + + LD+E+ Y REY+++++ + +D
Sbjct: 187 LALEEE-RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
Query: 221 QMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQFGIINNFRLGRLPTAPVDWSEINA 280
++K E Q+ Y Q+QL+KLKKTNVF ATFHI SGQFG INNFRLGRLP+ PV+W+EINA
Sbjct: 246 ELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINA 305
Query: 281 AWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEVLEDQ-KVLPLYGSGGFRFLWDTKF 339
AWGQTVLLL +LA K+ FQRY+LVPYGNHSY+E L D+ K LPLY SGG RF WD KF
Sbjct: 306 AWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKF 365
Query: 340 DAAMVAFLDCLQQFKEQVEMGNTGFCLPYRID--KGKIEDTASPPHAYSIKIQFNSEEHW 397
D AMVAFLDC+QQFKE+VE G T FCLPYR+D KGKIEDT +YSIK QFNSEE W
Sbjct: 366 DHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQW 425
Query: 398 TKALKYMLTNLKWALTWISSQF 419
TKALK+MLTNLKW L W+SSQF
Sbjct: 426 TKALKFMLTNLKWGLAWVSSQF 447
>L38932-1|AAB59573.1| 301|Homo sapiens protein ( Homo sapiens GT197
partial ORF mRNA, 3' end of cds. ).
Length = 301
Score = 332 bits (816), Expect = 1e-90
Identities = 153/226 (67%), Positives = 181/226 (80%), Gaps = 3/226 (1%)
Query: 197 LDKEQDVYWREYTKYRKDLMTTEDQMKFYECQLAYTQSQLEKLKKTNVFKATFHISDSGQ 256
LD+E+ Y REY+++++ + +D++K E Q+ Y Q+QL+KLKKTNVF ATFHI SGQ
Sbjct: 73 LDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQ 132
Query: 257 FGIINNFRLGRLPTAPVDWSEINAAWGQTVLLLSSLARKINFNFQRYKLVPYGNHSYIEV 316
FG INNFRLGRLP+ PV+W+EINAAWGQTVLLL +LA K+ FQRY+LVPYGNHSY+E
Sbjct: 133 FGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLES 192
Query: 317 LEDQ-KVLPLYGSGGFRFLWDTKFDAAMVAFLDCLQQFKEQVEMGNTGFCLPYRID--KG 373
L D+ K LPLY SGG RF WD KFD AMVAFLDC+QQFKE+VE G T FCLPYR+D KG
Sbjct: 193 LTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKG 252
Query: 374 KIEDTASPPHAYSIKIQFNSEEHWTKALKYMLTNLKWALTWISSQF 419
KIEDT +YSIK QFNSEE WTKALK+MLTNLKW L W+SSQF
Sbjct: 253 KIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQF 298
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.133 0.411
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 56,143,414
Number of Sequences: 224733
Number of extensions: 2051768
Number of successful extensions: 4070
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4047
Number of HSP's gapped (non-prelim): 13
length of query: 427
length of database: 73,234,838
effective HSP length: 92
effective length of query: 335
effective length of database: 52,559,402
effective search space: 17607399670
effective search space used: 17607399670
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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