SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000084-TA|BGIBMGA000084-PA|IPR007012|Poly(A) polymerase,
central region, IPR002934|DNA polymerase, beta-like region,
IPR007010|Poly(A) polymerase, RNA-binding region, IPR011068|Poly(A)
polymerase, C-terminal-like
         (596 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC113747-1|AAI13748.1|  736|Homo sapiens poly(A) polymerase gamm...   676   0.0  
BC111701-1|AAI11702.1|  736|Homo sapiens poly(A) polymerase gamm...   676   0.0  
AK023544-1|BAB14604.1|  675|Homo sapiens protein ( Homo sapiens ...   676   0.0  
AJ308101-1|CAC59751.1|  736|Homo sapiens poly(A) polymerase gamm...   676   0.0  
AF312211-1|AAK83701.1|  736|Homo sapiens neo-poly(A) polymerase ...   676   0.0  
AY029162-1|AAK31791.1|  736|Homo sapiens SRP RNA 3' adenylating ...   671   0.0  
BC110906-1|AAI10907.1|  506|Homo sapiens PAPOLG protein protein.      667   0.0  
AK021867-1|BAB13919.1|  501|Homo sapiens protein ( Homo sapiens ...   665   0.0  
BC036014-1|AAH36014.1|  745|Homo sapiens poly(A) polymerase alph...   665   0.0  
BC016738-1|AAH16738.1|  496|Homo sapiens Unknown (protein for IM...   650   0.0  
AC012498-1|AAY14832.1|  465|Homo sapiens unknown protein.             619   e-177
AF218840-1|AAF81013.1|  636|Homo sapiens testis-specific poly(A)...   605   e-172
AC092610-3|AAS07561.1|  636|Homo sapiens unknown protein.             605   e-172
BC036653-1|AAH36653.2|  637|Homo sapiens poly(A) polymerase beta...   603   e-172
AB284524-1|BAF41975.1|  637|Homo sapiens testis-specific poly(A)...   597   e-170
BC000927-1|AAH00927.1|  285|Homo sapiens PAPOLA protein protein.      404   e-112
AB209304-1|BAD92541.1|  382|Homo sapiens poly(A) polymerase gamm...   192   3e-48
AK024249-1|BAB14858.1|  302|Homo sapiens protein ( Homo sapiens ...    96   4e-19
AK023034-1|BAB14368.1|  302|Homo sapiens protein ( Homo sapiens ...    96   4e-19
AC011245-1|AAY14677.1|  270|Homo sapiens unknown protein.              61   1e-08
X15786-1|CAA33787.1|  899|Homo sapiens retII protein.                  32   6.6  
X12949-1|CAA31408.1|  860|Homo sapiens protein ( Human ret proto...    32   6.6  
M31213-1|AAA36524.1|  503|Homo sapiens protein ( Human papillary...    32   6.6  
DQ104207-1|AAZ57203.1|  776|Homo sapiens HOOK3-RET fusion protei...    32   6.6  
AY324389-1|AAQ86961.1| 1332|Homo sapiens neural interleukin 16 p...    32   6.6  
AK131530-1|BAD18668.1| 1331|Homo sapiens protein ( Homo sapiens ...    32   6.6  
AK124565-1|BAC85888.1| 1163|Homo sapiens protein ( Homo sapiens ...    32   6.6  
AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec...    32   6.6  

>BC113747-1|AAI13748.1|  736|Homo sapiens poly(A) polymerase gamma
           protein.
          Length = 736

 Score =  676 bits (1671), Expect = 0.0
 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553
           LTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH YL A +L ++++ +  +  +
Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514

Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596
             G L     +SKRLS      +SS  + NGT     A  S S ++  T
Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558


>BC111701-1|AAI11702.1|  736|Homo sapiens poly(A) polymerase gamma
           protein.
          Length = 736

 Score =  676 bits (1671), Expect = 0.0
 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553
           LTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH YL A +L ++++ +  +  +
Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514

Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596
             G L     +SKRLS      +SS  + NGT     A  S S ++  T
Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558


>AK023544-1|BAB14604.1|  675|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13482 fis, clone PLACE1003885, moderately
           similar to POLY(A) POLYMERASE (EC 2.7.7.19). ).
          Length = 675

 Score =  676 bits (1671), Expect = 0.0
 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 1   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 60

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 61  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 120

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 121 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 180

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 181 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 240

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 241 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 300

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 301 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 360

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 361 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 417

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 418 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 451

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553
           LTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH YL A +L ++++ +  +  +
Sbjct: 452 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 511

Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596
             G L     +SKRLS      +SS  + NGT     A  S S ++  T
Sbjct: 512 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 555


>AJ308101-1|CAC59751.1|  736|Homo sapiens poly(A) polymerase gamma
           protein.
          Length = 736

 Score =  676 bits (1671), Expect = 0.0
 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553
           LTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH YL A +L ++++ +  +  +
Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514

Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596
             G L     +SKRLS      +SS  + NGT     A  S S ++  T
Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558


>AF312211-1|AAK83701.1|  736|Homo sapiens neo-poly(A) polymerase
           protein.
          Length = 736

 Score =  676 bits (1671), Expect = 0.0
 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553
           LTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH YL A +L ++++ +  +  +
Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514

Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596
             G L     +SKRLS      +SS  + NGT     A  S S ++  T
Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558


>AY029162-1|AAK31791.1|  736|Homo sapiens SRP RNA 3' adenylating
           enzyme/pap2 protein.
          Length = 736

 Score =  671 bits (1659), Expect = 0.0
 Identities = 334/589 (56%), Positives = 423/589 (71%), Gaps = 44/589 (7%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A P+ ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPEEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQ +  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQSEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553
           LTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH YL A +L ++++ +  +  +
Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514

Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596
             G L     +SKRLS      +SS  + NGT     A  S S ++  T
Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558


>BC110906-1|AAI10907.1|  506|Homo sapiens PAPOLG protein protein.
          Length = 506

 Score =  667 bits (1647), Expect = 0.0
 Identities = 320/532 (60%), Positives = 400/532 (75%), Gaps = 33/532 (6%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRER 545
           LTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH YL A +L ++++
Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKK 506


>AK021867-1|BAB13919.1|  501|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11805 fis, clone HEMBA1006278, moderately
           similar to POLY(A) POLYMERASE (EC 2.7.7.19). ).
          Length = 501

 Score =  665 bits (1643), Expect = 0.0
 Identities = 320/527 (60%), Positives = 396/527 (75%), Gaps = 33/527 (6%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLL 540
           LTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH YL A +L
Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEIL 501


>BC036014-1|AAH36014.1|  745|Homo sapiens poly(A) polymerase alpha
           protein.
          Length = 745

 Score =  665 bits (1642), Expect = 0.0
 Identities = 328/533 (61%), Positives = 396/533 (74%), Gaps = 33/533 (6%)

Query: 17  PIKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRME 76
           P+      Q Q   K  G+TS IS A PK  D   T  L  +L PFGVFE E E+  R+ 
Sbjct: 4   PVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQRRIL 63

Query: 77  VLGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRH 136
           +LG L+ LV++WIR+ S  KN+P SV + VGG I+TFGSYRLGVH +GADIDALCVAPRH
Sbjct: 64  ILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRH 123

Query: 137 IERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFD 196
           ++R D+F +FYD LK Q +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+  D
Sbjct: 124 VDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLD 183

Query: 197 LRDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGY 256
           LRDD LLKNLD +C+RSLNGCRVTDEIL LVPNI+NFRLTLRAIKLWAKRH IYSN LG+
Sbjct: 184 LRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGF 243

Query: 257 LGGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPR 316
           LGGVSWAMLVARTCQLYPNA+ +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPR
Sbjct: 244 LGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPR 303

Query: 317 VNVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFE 376
           VN +DRYHLMPIITPAYPQQNST+NVS STR +++EEF+ GLA+TDEI+L K  W +LFE
Sbjct: 304 VNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFE 363

Query: 377 APNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNS 436
           APNFF +YKH+IVLLAS+ +   +L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+   S
Sbjct: 364 APNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---S 420

Query: 437 VPLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNV 492
            P                 P+E        DK E      +MW IGLVF+KT    N++V
Sbjct: 421 FPA----------------PKENP------DKEEFR----TMWVIGLVFKKTENSENLSV 454

Query: 493 DLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRER 545
           DLTYDI SFT  V  QA N+ M    + I A HV+RKQLHQ L   +L ++++
Sbjct: 455 DLTYDIQSFTDTVYRQAINSKMFEVDMKIAAMHVKRKQLHQLLPNHVLQKKKK 507


>BC016738-1|AAH16738.1|  496|Homo sapiens Unknown (protein for
           IMAGE:4106370) protein.
          Length = 496

 Score =  650 bits (1605), Expect = 0.0
 Identities = 313/517 (60%), Positives = 389/517 (75%), Gaps = 33/517 (6%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILYLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQ 530
           LTYDI SFT  V  QA N NML+EG+ IEA HV++K+
Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKK 491


>AC012498-1|AAY14832.1|  465|Homo sapiens unknown protein.
          Length = 465

 Score =  619 bits (1530), Expect = e-177
 Identities = 298/489 (60%), Positives = 369/489 (75%), Gaps = 33/489 (6%)

Query: 18  IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77
           + A     +Q+  K  G+TS IS A PK ID   T  L  ++ PFGVFE E E++HR+ V
Sbjct: 4   MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63

Query: 78  LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137
           LG L+ LV++WI D S  KN+PPSV  TVGG I+TFGSYRLGVH +GADIDALCVAPRH+
Sbjct: 64  LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123

Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197
           ER D+F +F++ LK Q  +++LRAVEDAFVPVIK  FDGIEIDL+FARLA++ I D+ DL
Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183

Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257
           RDD  L++LD +C+RSLNGCRVTDEIL LVPN   FRLTLRA+KLWAKR GIYSN LG+L
Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243

Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317
           GGVSWAMLVARTCQLYPNA  +TLVHKFFLVFS+W+WP PVLLKQP+  NL  PVWDPRV
Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303

Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377
           N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK  W +L E 
Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363

Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437
           PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+  LERN+ IT+AHVNP+ +   
Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420

Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493
                        PG       + E +K++      N+ SMWF+G++F +     +VN+D
Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454

Query: 494 LTYDISSFT 502
           LTYDI SFT
Sbjct: 455 LTYDIQSFT 463


>AF218840-1|AAF81013.1|  636|Homo sapiens testis-specific poly(A)
           polymerase protein.
          Length = 636

 Score =  605 bits (1494), Expect = e-172
 Identities = 304/522 (58%), Positives = 375/522 (71%), Gaps = 25/522 (4%)

Query: 34  GMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEVLGALHRLVRQWIRDES 93
           G++S IS A PK  D   T  L  +L PFGVFE E E+  R+ VL  L+ LV++WIR+ S
Sbjct: 21  GVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREIS 80

Query: 94  LRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHIERCDYFLTFYDLLKQQ 153
             K++P SV + VGG I+TFGSYRLGVH +GADIDALCVAP H++R D+F +FY  LK Q
Sbjct: 81  ESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQ 140

Query: 154 PQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDLRDDMLLKNLDQKCVRS 213
            +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+  DLRDD LLKNLD +C+RS
Sbjct: 141 EEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 200

Query: 214 LNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYLGGVSWAMLVARTCQLY 273
           LNGCRVTDEIL LVPNI+NFRLTLRAIKLWAK H IYSN LG+LGGVSWAMLVARTCQLY
Sbjct: 201 LNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLY 260

Query: 274 PNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRVNVADRYHLMPIITPAY 333
           PNA+ +TLV KFFLVFS+W+WP PVLLK+P+  NL  PVWDPRVN +DRYHLMPIITPAY
Sbjct: 261 PNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAY 320

Query: 334 PQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLAS 393
           PQQNST+NVS STR +++EEF+ GLA+T EI+L K  W +LFEAP+FF +YKH+IVLLAS
Sbjct: 321 PQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLAS 380

Query: 394 SASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGS 453
           +++    L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+   S P    N          
Sbjct: 381 ASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---SFPAPKENPDMEEFRTMW 437

Query: 454 TIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTN 513
            I       L K D  E++        I L ++           I SFT  V  QA N+ 
Sbjct: 438 VI----GLGLKKPDNSEIL-------SIDLTYD-----------IQSFTDTVYRQAVNSK 475

Query: 514 MLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPD 555
           M   G+ I A H+RRK+LHQ L   +L  ++  ++  +R  D
Sbjct: 476 MFEMGMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTD 517


>AC092610-3|AAS07561.1|  636|Homo sapiens unknown protein.
          Length = 636

 Score =  605 bits (1494), Expect = e-172
 Identities = 304/522 (58%), Positives = 375/522 (71%), Gaps = 25/522 (4%)

Query: 34  GMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEVLGALHRLVRQWIRDES 93
           G++S IS A PK  D   T  L  +L PFGVFE E E+  R+ VL  L+ LV++WIR+ S
Sbjct: 21  GVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREIS 80

Query: 94  LRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHIERCDYFLTFYDLLKQQ 153
             K++P SV + VGG I+TFGSYRLGVH +GADIDALCVAP H++R D+F +FY  LK Q
Sbjct: 81  ESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQ 140

Query: 154 PQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDLRDDMLLKNLDQKCVRS 213
            +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+  DLRDD LLKNLD +C+RS
Sbjct: 141 EEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 200

Query: 214 LNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYLGGVSWAMLVARTCQLY 273
           LNGCRVTDEIL LVPNI+NFRLTLRAIKLWAK H IYSN LG+LGGVSWAMLVARTCQLY
Sbjct: 201 LNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLY 260

Query: 274 PNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRVNVADRYHLMPIITPAY 333
           PNA+ +TLV KFFLVFS+W+WP PVLLK+P+  NL  PVWDPRVN +DRYHLMPIITPAY
Sbjct: 261 PNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAY 320

Query: 334 PQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLAS 393
           PQQNST+NVS STR +++EEF+ GLA+T EI+L K  W +LFEAP+FF +YKH+IVLLAS
Sbjct: 321 PQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLAS 380

Query: 394 SASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGS 453
           +++    L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+   S P    N          
Sbjct: 381 ASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---SFPAPKENPDMEEFRTMW 437

Query: 454 TIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTN 513
            I       L K D  E++        I L ++           I SFT  V  QA N+ 
Sbjct: 438 VI----GLGLKKPDNSEIL-------SIDLTYD-----------IQSFTDTVYRQAVNSK 475

Query: 514 MLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPD 555
           M   G+ I A H+RRK+LHQ L   +L  ++  ++  +R  D
Sbjct: 476 MFEMGMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTD 517


>BC036653-1|AAH36653.2|  637|Homo sapiens poly(A) polymerase beta
           (testis specific) protein.
          Length = 637

 Score =  603 bits (1490), Expect = e-172
 Identities = 303/522 (58%), Positives = 375/522 (71%), Gaps = 25/522 (4%)

Query: 34  GMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEVLGALHRLVRQWIRDES 93
           G++S IS A PK  D   T  L  +L PFGVFE E E+  R+ VL  L+ LV++WIR+ S
Sbjct: 22  GVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLDKLNNLVKEWIREIS 81

Query: 94  LRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHIERCDYFLTFYDLLKQQ 153
             K++P SV + VGG I+TFGSYRLGVH +GADIDALCVAP H++R D+F +FY  LK Q
Sbjct: 82  ESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQ 141

Query: 154 PQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDLRDDMLLKNLDQKCVRS 213
            +VKDLRAV++AFVPVIK+ FDGIEID+LFARLAL+ IP+  DLRDD LLKNLD +C+RS
Sbjct: 142 EEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 201

Query: 214 LNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYLGGVSWAMLVARTCQLY 273
           LNGCRVTDEIL LVPNI+NFRLTLRAIKLWAK H IYSN LG+LGGVSWAMLVARTCQLY
Sbjct: 202 LNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLY 261

Query: 274 PNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRVNVADRYHLMPIITPAY 333
           PNA+ +TLV KFFLVFS+W+WP PVLLK+P+  NL  PVWDPRVN +DRYHLMPIITPAY
Sbjct: 262 PNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAY 321

Query: 334 PQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLAS 393
           PQQNST+NVS STR +++EEF+ GLA+T EI+L K  W +LFEAP+FF +YKH+IVLLAS
Sbjct: 322 PQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLAS 381

Query: 394 SASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGS 453
           +++    L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+   S P    N          
Sbjct: 382 ASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---SFPAPKENPDMEEFRTMW 438

Query: 454 TIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTN 513
            I       L K D  E++        I L ++           I SFT  V  QA N+ 
Sbjct: 439 VI----GLGLKKPDNSEIL-------SIDLTYD-----------IQSFTDTVYRQAVNSK 476

Query: 514 MLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPD 555
           M   G+ I A H+RRK+LHQ L   +L  ++  ++  +R  D
Sbjct: 477 MFEMGMKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTD 518


>AB284524-1|BAF41975.1|  637|Homo sapiens testis-specific poly(A)
           polymerase protein.
          Length = 637

 Score =  597 bits (1474), Expect = e-170
 Identities = 301/522 (57%), Positives = 373/522 (71%), Gaps = 25/522 (4%)

Query: 34  GMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEVLGALHRLVRQWIRDES 93
           G++S IS A PK  D   T  L  +L PFGVFE E E+  R+ VL  L+ LV++WIR+ S
Sbjct: 22  GVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREIS 81

Query: 94  LRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHIERCDYFLTFYDLLKQQ 153
             K++P SV + VGG I+TFGSYRLGVH +GADIDALCVAP H++R D+F +FY  LK Q
Sbjct: 82  ESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQ 141

Query: 154 PQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDLRDDMLLKNLDQKCVRS 213
            +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+  DLRDD LLKNLD +C+RS
Sbjct: 142 EEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 201

Query: 214 LNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYLGGVSWAMLVARTCQLY 273
           LNGCRVTDEIL LVPNI+NFRLTLRAIKLWAK H IYSN LG+ GGVSWAMLVARTCQLY
Sbjct: 202 LNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFHGGVSWAMLVARTCQLY 261

Query: 274 PNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRVNVADRYHLMPIITPAY 333
           PNA+ +TLV K+FLVFS+W+WP PVLLK+P+  NL  PVWDPRVN +DRYHLMPIITPAY
Sbjct: 262 PNAVASTLVRKYFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAY 321

Query: 334 PQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLAS 393
           PQQNST+NVS STR +++E F+ GLA+T EI+L K  W +LFEAP+FF +YKH+IVLLAS
Sbjct: 322 PQQNSTYNVSISTRMVMIEVFKQGLAITHEILLTKAVWSKLFEAPSFFQKYKHYIVLLAS 381

Query: 394 SASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGS 453
           +++    L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+   S P    N          
Sbjct: 382 ASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---SFPAPKENPDMEEFRTMW 438

Query: 454 TIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTN 513
            I       L K D  E++        I L ++           I SFT  V  QA N+ 
Sbjct: 439 VI----GLGLKKPDNSEIL-------SIDLTYD-----------IQSFTDTVYRQAVNSK 476

Query: 514 MLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPD 555
           M   G+ I A H+RRK+LHQ L   +L  ++  ++  +R  D
Sbjct: 477 MFEMGMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTD 518


>BC000927-1|AAH00927.1|  285|Homo sapiens PAPOLA protein protein.
          Length = 285

 Score =  404 bits (995), Expect = e-112
 Identities = 190/276 (68%), Positives = 221/276 (80%)

Query: 17  PIKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRME 76
           P+      Q Q   K  G+TS IS A PK  D   T  L  +L PFGVFE E E+  R+ 
Sbjct: 4   PVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQRRIL 63

Query: 77  VLGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRH 136
           +LG L+ LV++WIR+ S  KN+P SV + VGG I+TFGSYRLGVH +GADIDALCVAPRH
Sbjct: 64  ILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRH 123

Query: 137 IERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFD 196
           ++R D+F +FYD LK Q +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+  D
Sbjct: 124 VDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLD 183

Query: 197 LRDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGY 256
           LRDD LLKNLD +C+RSLNGCRVTDEIL LVPNI+NFRLTLRAIKLWAKRH IYSN LG+
Sbjct: 184 LRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGF 243

Query: 257 LGGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQW 292
           LGGVSWAMLVARTCQLYPNA+ +TLVHKFFLVFS+W
Sbjct: 244 LGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKW 279


>AB209304-1|BAD92541.1|  382|Homo sapiens poly(A) polymerase gamma
           variant protein.
          Length = 382

 Score =  192 bits (468), Expect = 3e-48
 Identities = 110/260 (42%), Positives = 159/260 (61%), Gaps = 44/260 (16%)

Query: 347 RTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLASSASADDQLQWCGL 406
           RT+++EEF+ GLAVTDEI+ GK  W +L E PNFF +Y+H+IVL AS+++ ++ L+W GL
Sbjct: 1   RTVMVEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASASTEENHLEWVGL 60

Query: 407 IESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGSTIPRETSPELNKN 466
           +ESKIR L+  LERN+ IT+AHVNP+ +                PG       + E +K+
Sbjct: 61  VESKIRVLVGNLERNEFITLAHVNPQSF----------------PG-------NKEHHKD 97

Query: 467 DKGEVVVNHCSMWFIGLVFEKT----NVNVDLTYDISSFTKAVLYQAENTNMLREGLTIE 522
           +      N+ SMWF+G++F +     +VN+DLTYDI SFT  V  QA N NML+EG+ IE
Sbjct: 98  N------NYVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMKIE 151

Query: 523 ARHVRRKQLHQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLS------ESSNGSA 576
           A HV++KQLH YL A +L ++++ +  +  +  G L     +SKRLS      +SS  + 
Sbjct: 152 ATHVKKKQLHHYLPAEILQKKKKQSLSDVNRSSGGL-----QSKRLSLDSSCLDSSRDTD 206

Query: 577 NGTAETPKADASTSSTIACT 596
           NGT     A  S S ++  T
Sbjct: 207 NGTPFNSPASKSDSPSVGET 226


>AK024249-1|BAB14858.1|  302|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14187 fis, clone NT2RP2005776, weakly similar to
           POLY(A) POLYMERASE TYPE 2 (EC 2.7.7.19). ).
          Length = 302

 Score = 95.9 bits (228), Expect = 4e-19
 Identities = 54/129 (41%), Positives = 77/129 (59%), Gaps = 15/129 (11%)

Query: 478 MWFIGLVFEKT----NVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQ 533
           MWF+G++F +     +VN+DLTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH 
Sbjct: 1   MWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMRIEATHVKKKQLHH 60

Query: 534 YLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLS------ESSNGSANGTAETPKADA 587
           YL A +L ++++ +  +  +  G L     +SKRLS      +SS  + NGT     A  
Sbjct: 61  YLPAEILQKKKKQSLSDVNRSSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASK 115

Query: 588 STSSTIACT 596
           S S ++  T
Sbjct: 116 SDSPSVGET 124


>AK023034-1|BAB14368.1|  302|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12972 fis, clone NT2RP2005942, weakly similar to
           POLY(A) POLYMERASE (EC 2.7.7.19). ).
          Length = 302

 Score = 95.9 bits (228), Expect = 4e-19
 Identities = 54/129 (41%), Positives = 77/129 (59%), Gaps = 15/129 (11%)

Query: 478 MWFIGLVFEKT----NVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQ 533
           MWF+G++F +     +VN+DLTYDI SFT  V  QA N NML+EG+ IEA HV++KQLH 
Sbjct: 1   MWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHH 60

Query: 534 YLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLS------ESSNGSANGTAETPKADA 587
           YL A +L ++++ +  +  +  G L     +SKRLS      +SS  + NGT     A  
Sbjct: 61  YLPAEILQKKKKQSLSDVNRSSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASK 115

Query: 588 STSSTIACT 596
           S S ++  T
Sbjct: 116 SDSPSVGET 124


>AC011245-1|AAY14677.1|  270|Homo sapiens unknown protein.
          Length = 270

 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 37/95 (38%), Positives = 54/95 (56%), Gaps = 11/95 (11%)

Query: 508 QAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKR 567
           QA N NML+EG+ IEA HV++KQLH YL A +L ++++ +  +  +  G L     +SKR
Sbjct: 3   QANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNRSSGGL-----QSKR 57

Query: 568 LS------ESSNGSANGTAETPKADASTSSTIACT 596
           LS      +SS  + NGT     A  S S ++  T
Sbjct: 58  LSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 92


>X15786-1|CAA33787.1|  899|Homo sapiens retII protein.
          Length = 899

 Score = 31.9 bits (69), Expect = 6.6
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327
           P ALP+T +       S   WP   PV L + D  N GFP + P  +V   + L P
Sbjct: 834 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 888


>X12949-1|CAA31408.1|  860|Homo sapiens protein ( Human ret
           proto-oncogene mRNA for tyrosine kinase. ).
          Length = 860

 Score = 31.9 bits (69), Expect = 6.6
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327
           P ALP+T +       S   WP   PV L + D  N GFP + P  +V   + L P
Sbjct: 795 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 849


>M31213-1|AAA36524.1|  503|Homo sapiens protein ( Human papillary
           thyroid carcinoma-encoded protein mRNA, complete cds. ).
          Length = 503

 Score = 31.9 bits (69), Expect = 6.6
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327
           P ALP+T +       S   WP   PV L + D  N GFP + P  +V   + L P
Sbjct: 438 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 492


>DQ104207-1|AAZ57203.1|  776|Homo sapiens HOOK3-RET fusion protein
           protein.
          Length = 776

 Score = 31.9 bits (69), Expect = 6.6
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327
           P ALP+T +       S   WP   PV L + D  N GFP + P  +V   + L P
Sbjct: 711 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 765


>AY324389-1|AAQ86961.1| 1332|Homo sapiens neural interleukin 16
           precursor protein protein.
          Length = 1332

 Score = 31.9 bits (69), Expect = 6.6
 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 4/121 (3%)

Query: 472 VVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQL 531
           +++HC    + ++  +   + D         +AV    ENT   +E        V+R + 
Sbjct: 424 ILSHCDPGPVPIIVSR---HPDPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVKRLES 480

Query: 532 HQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLSESSNGS-ANGTAETPKADASTS 590
             +   +L   RE+ ++   R+    +      S  +S S  GS  +G+AE P +D   S
Sbjct: 481 SWHGRPTLEKEREKNSAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSSDVDIS 540

Query: 591 S 591
           +
Sbjct: 541 T 541


>AK131530-1|BAD18668.1| 1331|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16759 fis, clone BRACE3046450, highly  similar
           to Interleukin-16 precursor. ).
          Length = 1331

 Score = 31.9 bits (69), Expect = 6.6
 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 4/121 (3%)

Query: 472 VVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQL 531
           +++HC    + ++  +   + D         +AV    ENT   +E        V+R + 
Sbjct: 424 ILSHCDPGPVPIIVSR---HPDPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVKRLES 480

Query: 532 HQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLSESSNGS-ANGTAETPKADASTS 590
             +   +L   RE+ ++   R+    +      S  +S S  GS  +G+AE P +D   S
Sbjct: 481 SWHGRPTLEKEREKNSAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSSDVDIS 540

Query: 591 S 591
           +
Sbjct: 541 T 541


>AK124565-1|BAC85888.1| 1163|Homo sapiens protein ( Homo sapiens
           cDNA FLJ42574 fis, clone BRACE3008137, highly  similar
           to Interleukin-16 precursor. ).
          Length = 1163

 Score = 31.9 bits (69), Expect = 6.6
 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 4/121 (3%)

Query: 472 VVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQL 531
           +++HC    + ++  +   + D         +AV    ENT   +E        V+R + 
Sbjct: 256 ILSHCDPGPVPIIVSR---HPDPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVKRLES 312

Query: 532 HQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLSESSNGS-ANGTAETPKADASTS 590
             +   +L   RE+ ++   R+    +      S  +S S  GS  +G+AE P +D   S
Sbjct: 313 SWHGRPTLEKEREKNSAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSSDVDIS 372

Query: 591 S 591
           +
Sbjct: 373 T 373


>AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase receptor
            protein.
          Length = 1091

 Score = 31.9 bits (69), Expect = 6.6
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 274  PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327
            P ALP+T +       S   WP   PV L + D  N GFP + P  +V   + L P
Sbjct: 1026 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 1080


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.320    0.134    0.410 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,839,025
Number of Sequences: 224733
Number of extensions: 3980245
Number of successful extensions: 7545
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 7492
Number of HSP's gapped (non-prelim): 47
length of query: 596
length of database: 73,234,838
effective HSP length: 94
effective length of query: 502
effective length of database: 52,109,936
effective search space: 26159187872
effective search space used: 26159187872
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)

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