BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000084-TA|BGIBMGA000084-PA|IPR007012|Poly(A) polymerase, central region, IPR002934|DNA polymerase, beta-like region, IPR007010|Poly(A) polymerase, RNA-binding region, IPR011068|Poly(A) polymerase, C-terminal-like (596 letters) Database: human 224,733 sequences; 73,234,838 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BC113747-1|AAI13748.1| 736|Homo sapiens poly(A) polymerase gamm... 676 0.0 BC111701-1|AAI11702.1| 736|Homo sapiens poly(A) polymerase gamm... 676 0.0 AK023544-1|BAB14604.1| 675|Homo sapiens protein ( Homo sapiens ... 676 0.0 AJ308101-1|CAC59751.1| 736|Homo sapiens poly(A) polymerase gamm... 676 0.0 AF312211-1|AAK83701.1| 736|Homo sapiens neo-poly(A) polymerase ... 676 0.0 AY029162-1|AAK31791.1| 736|Homo sapiens SRP RNA 3' adenylating ... 671 0.0 BC110906-1|AAI10907.1| 506|Homo sapiens PAPOLG protein protein. 667 0.0 AK021867-1|BAB13919.1| 501|Homo sapiens protein ( Homo sapiens ... 665 0.0 BC036014-1|AAH36014.1| 745|Homo sapiens poly(A) polymerase alph... 665 0.0 BC016738-1|AAH16738.1| 496|Homo sapiens Unknown (protein for IM... 650 0.0 AC012498-1|AAY14832.1| 465|Homo sapiens unknown protein. 619 e-177 AF218840-1|AAF81013.1| 636|Homo sapiens testis-specific poly(A)... 605 e-172 AC092610-3|AAS07561.1| 636|Homo sapiens unknown protein. 605 e-172 BC036653-1|AAH36653.2| 637|Homo sapiens poly(A) polymerase beta... 603 e-172 AB284524-1|BAF41975.1| 637|Homo sapiens testis-specific poly(A)... 597 e-170 BC000927-1|AAH00927.1| 285|Homo sapiens PAPOLA protein protein. 404 e-112 AB209304-1|BAD92541.1| 382|Homo sapiens poly(A) polymerase gamm... 192 3e-48 AK024249-1|BAB14858.1| 302|Homo sapiens protein ( Homo sapiens ... 96 4e-19 AK023034-1|BAB14368.1| 302|Homo sapiens protein ( Homo sapiens ... 96 4e-19 AC011245-1|AAY14677.1| 270|Homo sapiens unknown protein. 61 1e-08 X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 32 6.6 X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto... 32 6.6 M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 32 6.6 DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 32 6.6 AY324389-1|AAQ86961.1| 1332|Homo sapiens neural interleukin 16 p... 32 6.6 AK131530-1|BAD18668.1| 1331|Homo sapiens protein ( Homo sapiens ... 32 6.6 AK124565-1|BAC85888.1| 1163|Homo sapiens protein ( Homo sapiens ... 32 6.6 AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec... 32 6.6 >BC113747-1|AAI13748.1| 736|Homo sapiens poly(A) polymerase gamma protein. Length = 736 Score = 676 bits (1671), Expect = 0.0 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553 LTYDI SFT V QA N NML+EG+ IEA HV++KQLH YL A +L ++++ + + + Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514 Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596 G L +SKRLS +SS + NGT A S S ++ T Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558 >BC111701-1|AAI11702.1| 736|Homo sapiens poly(A) polymerase gamma protein. Length = 736 Score = 676 bits (1671), Expect = 0.0 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553 LTYDI SFT V QA N NML+EG+ IEA HV++KQLH YL A +L ++++ + + + Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514 Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596 G L +SKRLS +SS + NGT A S S ++ T Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558 >AK023544-1|BAB14604.1| 675|Homo sapiens protein ( Homo sapiens cDNA FLJ13482 fis, clone PLACE1003885, moderately similar to POLY(A) POLYMERASE (EC 2.7.7.19). ). Length = 675 Score = 676 bits (1671), Expect = 0.0 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 1 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 60 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 61 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 120 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 121 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 180 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 181 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 240 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 241 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 300 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 301 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 360 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 361 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 417 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 418 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 451 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553 LTYDI SFT V QA N NML+EG+ IEA HV++KQLH YL A +L ++++ + + + Sbjct: 452 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 511 Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596 G L +SKRLS +SS + NGT A S S ++ T Sbjct: 512 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 555 >AJ308101-1|CAC59751.1| 736|Homo sapiens poly(A) polymerase gamma protein. Length = 736 Score = 676 bits (1671), Expect = 0.0 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553 LTYDI SFT V QA N NML+EG+ IEA HV++KQLH YL A +L ++++ + + + Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514 Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596 G L +SKRLS +SS + NGT A S S ++ T Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558 >AF312211-1|AAK83701.1| 736|Homo sapiens neo-poly(A) polymerase protein. Length = 736 Score = 676 bits (1671), Expect = 0.0 Identities = 336/589 (57%), Positives = 424/589 (71%), Gaps = 44/589 (7%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553 LTYDI SFT V QA N NML+EG+ IEA HV++KQLH YL A +L ++++ + + + Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514 Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596 G L +SKRLS +SS + NGT A S S ++ T Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558 >AY029162-1|AAK31791.1| 736|Homo sapiens SRP RNA 3' adenylating enzyme/pap2 protein. Length = 736 Score = 671 bits (1659), Expect = 0.0 Identities = 334/589 (56%), Positives = 423/589 (71%), Gaps = 44/589 (7%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A P+ ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPEEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQ + NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQSEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRK 553 LTYDI SFT V QA N NML+EG+ IEA HV++KQLH YL A +L ++++ + + + Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNR 514 Query: 554 PDGALTHPPKKSKRLS------ESSNGSANGTAETPKADASTSSTIACT 596 G L +SKRLS +SS + NGT A S S ++ T Sbjct: 515 SSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 558 >BC110906-1|AAI10907.1| 506|Homo sapiens PAPOLG protein protein. Length = 506 Score = 667 bits (1647), Expect = 0.0 Identities = 320/532 (60%), Positives = 400/532 (75%), Gaps = 33/532 (6%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRER 545 LTYDI SFT V QA N NML+EG+ IEA HV++KQLH YL A +L ++++ Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKK 506 >AK021867-1|BAB13919.1| 501|Homo sapiens protein ( Homo sapiens cDNA FLJ11805 fis, clone HEMBA1006278, moderately similar to POLY(A) POLYMERASE (EC 2.7.7.19). ). Length = 501 Score = 665 bits (1643), Expect = 0.0 Identities = 320/527 (60%), Positives = 396/527 (75%), Gaps = 33/527 (6%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLL 540 LTYDI SFT V QA N NML+EG+ IEA HV++KQLH YL A +L Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLPAEIL 501 >BC036014-1|AAH36014.1| 745|Homo sapiens poly(A) polymerase alpha protein. Length = 745 Score = 665 bits (1642), Expect = 0.0 Identities = 328/533 (61%), Positives = 396/533 (74%), Gaps = 33/533 (6%) Query: 17 PIKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRME 76 P+ Q Q K G+TS IS A PK D T L +L PFGVFE E E+ R+ Sbjct: 4 PVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQRRIL 63 Query: 77 VLGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRH 136 +LG L+ LV++WIR+ S KN+P SV + VGG I+TFGSYRLGVH +GADIDALCVAPRH Sbjct: 64 ILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRH 123 Query: 137 IERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFD 196 ++R D+F +FYD LK Q +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+ D Sbjct: 124 VDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLD 183 Query: 197 LRDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGY 256 LRDD LLKNLD +C+RSLNGCRVTDEIL LVPNI+NFRLTLRAIKLWAKRH IYSN LG+ Sbjct: 184 LRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGF 243 Query: 257 LGGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPR 316 LGGVSWAMLVARTCQLYPNA+ +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPR Sbjct: 244 LGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPR 303 Query: 317 VNVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFE 376 VN +DRYHLMPIITPAYPQQNST+NVS STR +++EEF+ GLA+TDEI+L K W +LFE Sbjct: 304 VNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFE 363 Query: 377 APNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNS 436 APNFF +YKH+IVLLAS+ + +L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+ S Sbjct: 364 APNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---S 420 Query: 437 VPLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNV 492 P P+E DK E +MW IGLVF+KT N++V Sbjct: 421 FPA----------------PKENP------DKEEFR----TMWVIGLVFKKTENSENLSV 454 Query: 493 DLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRER 545 DLTYDI SFT V QA N+ M + I A HV+RKQLHQ L +L ++++ Sbjct: 455 DLTYDIQSFTDTVYRQAINSKMFEVDMKIAAMHVKRKQLHQLLPNHVLQKKKK 507 >BC016738-1|AAH16738.1| 496|Homo sapiens Unknown (protein for IMAGE:4106370) protein. Length = 496 Score = 650 bits (1605), Expect = 0.0 Identities = 313/517 (60%), Positives = 389/517 (75%), Gaps = 33/517 (6%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILYLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQ 530 LTYDI SFT V QA N NML+EG+ IEA HV++K+ Sbjct: 455 LTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKK 491 >AC012498-1|AAY14832.1| 465|Homo sapiens unknown protein. Length = 465 Score = 619 bits (1530), Expect = e-177 Identities = 298/489 (60%), Positives = 369/489 (75%), Gaps = 33/489 (6%) Query: 18 IKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEV 77 + A +Q+ K G+TS IS A PK ID T L ++ PFGVFE E E++HR+ V Sbjct: 4 MSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVV 63 Query: 78 LGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHI 137 LG L+ LV++WI D S KN+PPSV TVGG I+TFGSYRLGVH +GADIDALCVAPRH+ Sbjct: 64 LGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHV 123 Query: 138 ERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDL 197 ER D+F +F++ LK Q +++LRAVEDAFVPVIK FDGIEIDL+FARLA++ I D+ DL Sbjct: 124 ERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDL 183 Query: 198 RDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYL 257 RDD L++LD +C+RSLNGCRVTDEIL LVPN FRLTLRA+KLWAKR GIYSN LG+L Sbjct: 184 RDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFL 243 Query: 258 GGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRV 317 GGVSWAMLVARTCQLYPNA +TLVHKFFLVFS+W+WP PVLLKQP+ NL PVWDPRV Sbjct: 244 GGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRV 303 Query: 318 NVADRYHLMPIITPAYPQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEA 377 N +DRYHLMPIITPAYPQQNST+NVS STRT+++EEF+ GLAVTDEI+ GK W +L E Sbjct: 304 NPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEP 363 Query: 378 PNFFSRYKHFIVLLASSASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSV 437 PNFF +Y+H+IVL AS+++ ++ L+W GL+ESKIR L+ LERN+ IT+AHVNP+ + Sbjct: 364 PNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF--- 420 Query: 438 PLNTNNGQPLALPPGSTIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKT----NVNVD 493 PG + E +K++ N+ SMWF+G++F + +VN+D Sbjct: 421 -------------PG-------NKEHHKDN------NYVSMWFLGIIFRRVENAESVNID 454 Query: 494 LTYDISSFT 502 LTYDI SFT Sbjct: 455 LTYDIQSFT 463 >AF218840-1|AAF81013.1| 636|Homo sapiens testis-specific poly(A) polymerase protein. Length = 636 Score = 605 bits (1494), Expect = e-172 Identities = 304/522 (58%), Positives = 375/522 (71%), Gaps = 25/522 (4%) Query: 34 GMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEVLGALHRLVRQWIRDES 93 G++S IS A PK D T L +L PFGVFE E E+ R+ VL L+ LV++WIR+ S Sbjct: 21 GVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREIS 80 Query: 94 LRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHIERCDYFLTFYDLLKQQ 153 K++P SV + VGG I+TFGSYRLGVH +GADIDALCVAP H++R D+F +FY LK Q Sbjct: 81 ESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQ 140 Query: 154 PQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDLRDDMLLKNLDQKCVRS 213 +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+ DLRDD LLKNLD +C+RS Sbjct: 141 EEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 200 Query: 214 LNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYLGGVSWAMLVARTCQLY 273 LNGCRVTDEIL LVPNI+NFRLTLRAIKLWAK H IYSN LG+LGGVSWAMLVARTCQLY Sbjct: 201 LNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLY 260 Query: 274 PNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRVNVADRYHLMPIITPAY 333 PNA+ +TLV KFFLVFS+W+WP PVLLK+P+ NL PVWDPRVN +DRYHLMPIITPAY Sbjct: 261 PNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAY 320 Query: 334 PQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLAS 393 PQQNST+NVS STR +++EEF+ GLA+T EI+L K W +LFEAP+FF +YKH+IVLLAS Sbjct: 321 PQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLAS 380 Query: 394 SASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGS 453 +++ L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+ S P N Sbjct: 381 ASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---SFPAPKENPDMEEFRTMW 437 Query: 454 TIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTN 513 I L K D E++ I L ++ I SFT V QA N+ Sbjct: 438 VI----GLGLKKPDNSEIL-------SIDLTYD-----------IQSFTDTVYRQAVNSK 475 Query: 514 MLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPD 555 M G+ I A H+RRK+LHQ L +L ++ ++ +R D Sbjct: 476 MFEMGMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTD 517 >AC092610-3|AAS07561.1| 636|Homo sapiens unknown protein. Length = 636 Score = 605 bits (1494), Expect = e-172 Identities = 304/522 (58%), Positives = 375/522 (71%), Gaps = 25/522 (4%) Query: 34 GMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEVLGALHRLVRQWIRDES 93 G++S IS A PK D T L +L PFGVFE E E+ R+ VL L+ LV++WIR+ S Sbjct: 21 GVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREIS 80 Query: 94 LRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHIERCDYFLTFYDLLKQQ 153 K++P SV + VGG I+TFGSYRLGVH +GADIDALCVAP H++R D+F +FY LK Q Sbjct: 81 ESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQ 140 Query: 154 PQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDLRDDMLLKNLDQKCVRS 213 +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+ DLRDD LLKNLD +C+RS Sbjct: 141 EEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 200 Query: 214 LNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYLGGVSWAMLVARTCQLY 273 LNGCRVTDEIL LVPNI+NFRLTLRAIKLWAK H IYSN LG+LGGVSWAMLVARTCQLY Sbjct: 201 LNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLY 260 Query: 274 PNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRVNVADRYHLMPIITPAY 333 PNA+ +TLV KFFLVFS+W+WP PVLLK+P+ NL PVWDPRVN +DRYHLMPIITPAY Sbjct: 261 PNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAY 320 Query: 334 PQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLAS 393 PQQNST+NVS STR +++EEF+ GLA+T EI+L K W +LFEAP+FF +YKH+IVLLAS Sbjct: 321 PQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLAS 380 Query: 394 SASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGS 453 +++ L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+ S P N Sbjct: 381 ASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---SFPAPKENPDMEEFRTMW 437 Query: 454 TIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTN 513 I L K D E++ I L ++ I SFT V QA N+ Sbjct: 438 VI----GLGLKKPDNSEIL-------SIDLTYD-----------IQSFTDTVYRQAVNSK 475 Query: 514 MLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPD 555 M G+ I A H+RRK+LHQ L +L ++ ++ +R D Sbjct: 476 MFEMGMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTD 517 >BC036653-1|AAH36653.2| 637|Homo sapiens poly(A) polymerase beta (testis specific) protein. Length = 637 Score = 603 bits (1490), Expect = e-172 Identities = 303/522 (58%), Positives = 375/522 (71%), Gaps = 25/522 (4%) Query: 34 GMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEVLGALHRLVRQWIRDES 93 G++S IS A PK D T L +L PFGVFE E E+ R+ VL L+ LV++WIR+ S Sbjct: 22 GVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLDKLNNLVKEWIREIS 81 Query: 94 LRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHIERCDYFLTFYDLLKQQ 153 K++P SV + VGG I+TFGSYRLGVH +GADIDALCVAP H++R D+F +FY LK Q Sbjct: 82 ESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQ 141 Query: 154 PQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDLRDDMLLKNLDQKCVRS 213 +VKDLRAV++AFVPVIK+ FDGIEID+LFARLAL+ IP+ DLRDD LLKNLD +C+RS Sbjct: 142 EEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 201 Query: 214 LNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYLGGVSWAMLVARTCQLY 273 LNGCRVTDEIL LVPNI+NFRLTLRAIKLWAK H IYSN LG+LGGVSWAMLVARTCQLY Sbjct: 202 LNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLY 261 Query: 274 PNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRVNVADRYHLMPIITPAY 333 PNA+ +TLV KFFLVFS+W+WP PVLLK+P+ NL PVWDPRVN +DRYHLMPIITPAY Sbjct: 262 PNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAY 321 Query: 334 PQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLAS 393 PQQNST+NVS STR +++EEF+ GLA+T EI+L K W +LFEAP+FF +YKH+IVLLAS Sbjct: 322 PQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLAS 381 Query: 394 SASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGS 453 +++ L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+ S P N Sbjct: 382 ASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---SFPAPKENPDMEEFRTMW 438 Query: 454 TIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTN 513 I L K D E++ I L ++ I SFT V QA N+ Sbjct: 439 VI----GLGLKKPDNSEIL-------SIDLTYD-----------IQSFTDTVYRQAVNSK 476 Query: 514 MLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPD 555 M G+ I A H+RRK+LHQ L +L ++ ++ +R D Sbjct: 477 MFEMGMKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTD 518 >AB284524-1|BAF41975.1| 637|Homo sapiens testis-specific poly(A) polymerase protein. Length = 637 Score = 597 bits (1474), Expect = e-170 Identities = 301/522 (57%), Positives = 373/522 (71%), Gaps = 25/522 (4%) Query: 34 GMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRMEVLGALHRLVRQWIRDES 93 G++S IS A PK D T L +L PFGVFE E E+ R+ VL L+ LV++WIR+ S Sbjct: 22 GVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREIS 81 Query: 94 LRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRHIERCDYFLTFYDLLKQQ 153 K++P SV + VGG I+TFGSYRLGVH +GADIDALCVAP H++R D+F +FY LK Q Sbjct: 82 ESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQ 141 Query: 154 PQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFDLRDDMLLKNLDQKCVRS 213 +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+ DLRDD LLKNLD +C+RS Sbjct: 142 EEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 201 Query: 214 LNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGYLGGVSWAMLVARTCQLY 273 LNGCRVTDEIL LVPNI+NFRLTLRAIKLWAK H IYSN LG+ GGVSWAMLVARTCQLY Sbjct: 202 LNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFHGGVSWAMLVARTCQLY 261 Query: 274 PNALPATLVHKFFLVFSQWKWPQPVLLKQPDHVNLGFPVWDPRVNVADRYHLMPIITPAY 333 PNA+ +TLV K+FLVFS+W+WP PVLLK+P+ NL PVWDPRVN +DRYHLMPIITPAY Sbjct: 262 PNAVASTLVRKYFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAY 321 Query: 334 PQQNSTFNVSASTRTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLAS 393 PQQNST+NVS STR +++E F+ GLA+T EI+L K W +LFEAP+FF +YKH+IVLLAS Sbjct: 322 PQQNSTYNVSISTRMVMIEVFKQGLAITHEILLTKAVWSKLFEAPSFFQKYKHYIVLLAS 381 Query: 394 SASADDQLQWCGLIESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGS 453 +++ L+W GL+ESKIR L+ +LE+N+ IT+AHVNP+ S P N Sbjct: 382 ASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ---SFPAPKENPDMEEFRTMW 438 Query: 454 TIPRETSPELNKNDKGEVVVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTN 513 I L K D E++ I L ++ I SFT V QA N+ Sbjct: 439 VI----GLGLKKPDNSEIL-------SIDLTYD-----------IQSFTDTVYRQAVNSK 476 Query: 514 MLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPD 555 M G+ I A H+RRK+LHQ L +L ++ ++ +R D Sbjct: 477 MFEMGMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTD 518 >BC000927-1|AAH00927.1| 285|Homo sapiens PAPOLA protein protein. Length = 285 Score = 404 bits (995), Expect = e-112 Identities = 190/276 (68%), Positives = 221/276 (80%) Query: 17 PIKATNEYQNQQNLKTLGMTSAISTAGPKPIDIEKTNDLKVSLTPFGVFESEAEMHHRME 76 P+ Q Q K G+TS IS A PK D T L +L PFGVFE E E+ R+ Sbjct: 4 PVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQRRIL 63 Query: 77 VLGALHRLVRQWIRDESLRKNMPPSVADTVGGNIYTFGSYRLGVHHRGADIDALCVAPRH 136 +LG L+ LV++WIR+ S KN+P SV + VGG I+TFGSYRLGVH +GADIDALCVAPRH Sbjct: 64 ILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRH 123 Query: 137 IERCDYFLTFYDLLKQQPQVKDLRAVEDAFVPVIKMNFDGIEIDLLFARLALKEIPDSFD 196 ++R D+F +FYD LK Q +VKDLRAVE+AFVPVIK+ FDGIEID+LFARLAL+ IP+ D Sbjct: 124 VDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLD 183 Query: 197 LRDDMLLKNLDQKCVRSLNGCRVTDEILRLVPNINNFRLTLRAIKLWAKRHGIYSNTLGY 256 LRDD LLKNLD +C+RSLNGCRVTDEIL LVPNI+NFRLTLRAIKLWAKRH IYSN LG+ Sbjct: 184 LRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGF 243 Query: 257 LGGVSWAMLVARTCQLYPNALPATLVHKFFLVFSQW 292 LGGVSWAMLVARTCQLYPNA+ +TLVHKFFLVFS+W Sbjct: 244 LGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKW 279 >AB209304-1|BAD92541.1| 382|Homo sapiens poly(A) polymerase gamma variant protein. Length = 382 Score = 192 bits (468), Expect = 3e-48 Identities = 110/260 (42%), Positives = 159/260 (61%), Gaps = 44/260 (16%) Query: 347 RTIIMEEFRLGLAVTDEIMLGKCGWERLFEAPNFFSRYKHFIVLLASSASADDQLQWCGL 406 RT+++EEF+ GLAVTDEI+ GK W +L E PNFF +Y+H+IVL AS+++ ++ L+W GL Sbjct: 1 RTVMVEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASASTEENHLEWVGL 60 Query: 407 IESKIRHLIATLERNQHITIAHVNPECYNSVPLNTNNGQPLALPPGSTIPRETSPELNKN 466 +ESKIR L+ LERN+ IT+AHVNP+ + PG + E +K+ Sbjct: 61 VESKIRVLVGNLERNEFITLAHVNPQSF----------------PG-------NKEHHKD 97 Query: 467 DKGEVVVNHCSMWFIGLVFEKT----NVNVDLTYDISSFTKAVLYQAENTNMLREGLTIE 522 + N+ SMWF+G++F + +VN+DLTYDI SFT V QA N NML+EG+ IE Sbjct: 98 N------NYVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMKIE 151 Query: 523 ARHVRRKQLHQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLS------ESSNGSA 576 A HV++KQLH YL A +L ++++ + + + G L +SKRLS +SS + Sbjct: 152 ATHVKKKQLHHYLPAEILQKKKKQSLSDVNRSSGGL-----QSKRLSLDSSCLDSSRDTD 206 Query: 577 NGTAETPKADASTSSTIACT 596 NGT A S S ++ T Sbjct: 207 NGTPFNSPASKSDSPSVGET 226 >AK024249-1|BAB14858.1| 302|Homo sapiens protein ( Homo sapiens cDNA FLJ14187 fis, clone NT2RP2005776, weakly similar to POLY(A) POLYMERASE TYPE 2 (EC 2.7.7.19). ). Length = 302 Score = 95.9 bits (228), Expect = 4e-19 Identities = 54/129 (41%), Positives = 77/129 (59%), Gaps = 15/129 (11%) Query: 478 MWFIGLVFEKT----NVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQ 533 MWF+G++F + +VN+DLTYDI SFT V QA N NML+EG+ IEA HV++KQLH Sbjct: 1 MWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMRIEATHVKKKQLHH 60 Query: 534 YLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLS------ESSNGSANGTAETPKADA 587 YL A +L ++++ + + + G L +SKRLS +SS + NGT A Sbjct: 61 YLPAEILQKKKKQSLSDVNRSSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASK 115 Query: 588 STSSTIACT 596 S S ++ T Sbjct: 116 SDSPSVGET 124 >AK023034-1|BAB14368.1| 302|Homo sapiens protein ( Homo sapiens cDNA FLJ12972 fis, clone NT2RP2005942, weakly similar to POLY(A) POLYMERASE (EC 2.7.7.19). ). Length = 302 Score = 95.9 bits (228), Expect = 4e-19 Identities = 54/129 (41%), Positives = 77/129 (59%), Gaps = 15/129 (11%) Query: 478 MWFIGLVFEKT----NVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQLHQ 533 MWF+G++F + +VN+DLTYDI SFT V QA N NML+EG+ IEA HV++KQLH Sbjct: 1 MWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHH 60 Query: 534 YLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLS------ESSNGSANGTAETPKADA 587 YL A +L ++++ + + + G L +SKRLS +SS + NGT A Sbjct: 61 YLPAEILQKKKKQSLSDVNRSSGGL-----QSKRLSLDSSCLDSSRDTDNGTPFNSPASK 115 Query: 588 STSSTIACT 596 S S ++ T Sbjct: 116 SDSPSVGET 124 >AC011245-1|AAY14677.1| 270|Homo sapiens unknown protein. Length = 270 Score = 60.9 bits (141), Expect = 1e-08 Identities = 37/95 (38%), Positives = 54/95 (56%), Gaps = 11/95 (11%) Query: 508 QAENTNMLREGLTIEARHVRRKQLHQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKR 567 QA N NML+EG+ IEA HV++KQLH YL A +L ++++ + + + G L +SKR Sbjct: 3 QANNINMLKEGMKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNRSSGGL-----QSKR 57 Query: 568 LS------ESSNGSANGTAETPKADASTSSTIACT 596 LS +SS + NGT A S S ++ T Sbjct: 58 LSLDSSCLDSSRDTDNGTPFNSPASKSDSPSVGET 92 >X15786-1|CAA33787.1| 899|Homo sapiens retII protein. Length = 899 Score = 31.9 bits (69), Expect = 6.6 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327 P ALP+T + S WP PV L + D N GFP + P +V + L P Sbjct: 834 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 888 >X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto-oncogene mRNA for tyrosine kinase. ). Length = 860 Score = 31.9 bits (69), Expect = 6.6 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327 P ALP+T + S WP PV L + D N GFP + P +V + L P Sbjct: 795 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 849 >M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary thyroid carcinoma-encoded protein mRNA, complete cds. ). Length = 503 Score = 31.9 bits (69), Expect = 6.6 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327 P ALP+T + S WP PV L + D N GFP + P +V + L P Sbjct: 438 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 492 >DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protein protein. Length = 776 Score = 31.9 bits (69), Expect = 6.6 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327 P ALP+T + S WP PV L + D N GFP + P +V + L P Sbjct: 711 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 765 >AY324389-1|AAQ86961.1| 1332|Homo sapiens neural interleukin 16 precursor protein protein. Length = 1332 Score = 31.9 bits (69), Expect = 6.6 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 4/121 (3%) Query: 472 VVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQL 531 +++HC + ++ + + D +AV ENT +E V+R + Sbjct: 424 ILSHCDPGPVPIIVSR---HPDPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVKRLES 480 Query: 532 HQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLSESSNGS-ANGTAETPKADASTS 590 + +L RE+ ++ R+ + S +S S GS +G+AE P +D S Sbjct: 481 SWHGRPTLEKEREKNSAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSSDVDIS 540 Query: 591 S 591 + Sbjct: 541 T 541 >AK131530-1|BAD18668.1| 1331|Homo sapiens protein ( Homo sapiens cDNA FLJ16759 fis, clone BRACE3046450, highly similar to Interleukin-16 precursor. ). Length = 1331 Score = 31.9 bits (69), Expect = 6.6 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 4/121 (3%) Query: 472 VVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQL 531 +++HC + ++ + + D +AV ENT +E V+R + Sbjct: 424 ILSHCDPGPVPIIVSR---HPDPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVKRLES 480 Query: 532 HQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLSESSNGS-ANGTAETPKADASTS 590 + +L RE+ ++ R+ + S +S S GS +G+AE P +D S Sbjct: 481 SWHGRPTLEKEREKNSAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSSDVDIS 540 Query: 591 S 591 + Sbjct: 541 T 541 >AK124565-1|BAC85888.1| 1163|Homo sapiens protein ( Homo sapiens cDNA FLJ42574 fis, clone BRACE3008137, highly similar to Interleukin-16 precursor. ). Length = 1163 Score = 31.9 bits (69), Expect = 6.6 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 4/121 (3%) Query: 472 VVNHCSMWFIGLVFEKTNVNVDLTYDISSFTKAVLYQAENTNMLREGLTIEARHVRRKQL 531 +++HC + ++ + + D +AV ENT +E V+R + Sbjct: 256 ILSHCDPGPVPIIVSR---HPDPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVKRLES 312 Query: 532 HQYLSASLLCRRERTASGNKRKPDGALTHPPKKSKRLSESSNGS-ANGTAETPKADASTS 590 + +L RE+ ++ R+ + S +S S GS +G+AE P +D S Sbjct: 313 SWHGRPTLEKEREKNSAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSSDVDIS 372 Query: 591 S 591 + Sbjct: 373 T 373 >AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase receptor protein. Length = 1091 Score = 31.9 bits (69), Expect = 6.6 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 274 PNALPATLVHKFFLVFSQWKWP--QPVLLKQPDHVNLGFPVWDPRVNVADRYHLMP 327 P ALP+T + S WP PV L + D N GFP + P +V + L P Sbjct: 1026 PRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRY-PNDSVYANWMLSP 1080 Database: human Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 73,234,838 Number of sequences in database: 224,733 Lambda K H 0.320 0.134 0.410 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 90,839,025 Number of Sequences: 224733 Number of extensions: 3980245 Number of successful extensions: 7545 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 7492 Number of HSP's gapped (non-prelim): 47 length of query: 596 length of database: 73,234,838 effective HSP length: 94 effective length of query: 502 effective length of database: 52,109,936 effective search space: 26159187872 effective search space used: 26159187872 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 68 (31.5 bits)
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