Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000078-TA|BGIBMGA000078-PA|IPR012496|TMC
(612 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B631D Cluster: PREDICTED: similar to tmc7 prote... 483 e-135
UniRef50_UPI000051A81F Cluster: PREDICTED: similar to transmembr... 469 e-130
UniRef50_UPI0000D55B64 Cluster: PREDICTED: similar to transmembr... 460 e-128
UniRef50_Q17MQ2 Cluster: Tmc7 protein; n=1; Aedes aegypti|Rep: T... 353 8e-96
UniRef50_Q7Z402 Cluster: Transmembrane channel-like protein 7; n... 231 4e-59
UniRef50_Q5YCC5 Cluster: Transmembrane channel-like protein 7; n... 227 7e-58
UniRef50_A7RJT8 Cluster: Predicted protein; n=1; Nematostella ve... 196 1e-48
UniRef50_UPI00006A062E Cluster: transmembrane channel-like 4; n=... 160 1e-37
UniRef50_A7SUG1 Cluster: Predicted protein; n=1; Nematostella ve... 156 1e-36
UniRef50_UPI000069E015 Cluster: Transmembrane channel-like prote... 136 2e-30
UniRef50_Q7T1T6 Cluster: Tmc4 protein; n=4; Clupeocephala|Rep: T... 131 5e-29
UniRef50_Q7Z013 Cluster: TmcC-like protein; n=2; Anopheles gambi... 128 3e-28
UniRef50_Q8IU68 Cluster: Transmembrane channel-like protein 8; n... 128 3e-28
UniRef50_UPI00015A529C Cluster: UPI00015A529C related cluster; n... 120 1e-25
UniRef50_UPI000155461D Cluster: PREDICTED: similar to EGDC3042; ... 116 2e-24
UniRef50_Q7Z404 Cluster: Transmembrane channel-like protein 4; n... 115 4e-24
UniRef50_UPI0000E48F40 Cluster: PREDICTED: similar to Tmc5 prote... 108 4e-22
UniRef50_Q4S012 Cluster: Chromosome 18 SCAF14786, whole genome s... 103 1e-20
UniRef50_UPI0000E2410B Cluster: PREDICTED: transmembrane channel... 100 1e-19
UniRef50_Q6UXY8 Cluster: Transmembrane channel-like protein 5; n... 99 2e-19
UniRef50_UPI0000F20C6E Cluster: PREDICTED: hypothetical protein;... 99 3e-19
UniRef50_A7RLV1 Cluster: Predicted protein; n=1; Nematostella ve... 97 1e-18
UniRef50_UPI00015B58C9 Cluster: PREDICTED: similar to tmc6 prote... 95 5e-18
UniRef50_UPI0000D56BEC Cluster: PREDICTED: similar to transmembr... 94 9e-18
UniRef50_Q7Z5M5 Cluster: Transmembrane channel-like protein 3; n... 82 4e-14
UniRef50_Q4S011 Cluster: Chromosome 18 SCAF14786, whole genome s... 78 8e-13
UniRef50_UPI00015A7BA3 Cluster: Transmembrane channel-like prote... 72 4e-11
UniRef50_Q4SN83 Cluster: Chromosome 8 SCAF14543, whole genome sh... 72 5e-11
UniRef50_Q7Z015 Cluster: TmcA-like protein; n=3; Culicidae|Rep: ... 69 3e-10
UniRef50_Q8TDI7 Cluster: Transmembrane channel-like protein 2; n... 69 4e-10
UniRef50_A7SZG0 Cluster: Predicted protein; n=1; Nematostella ve... 69 5e-10
UniRef50_UPI0000DB7B12 Cluster: PREDICTED: similar to CG3280-PA,... 66 2e-09
UniRef50_UPI0001556598 Cluster: PREDICTED: similar to Tmc8 prote... 63 2e-08
UniRef50_Q5YCC8 Cluster: Transmembrane channel-like 2; n=6; Amni... 62 4e-08
UniRef50_Q9VT17 Cluster: CG3280-PA; n=1; Drosophila melanogaster... 62 6e-08
UniRef50_Q11069 Cluster: TMC family membrane protein B0416.1; n=... 60 1e-07
UniRef50_Q6DH78 Cluster: Zgc:92610; n=2; Danio rerio|Rep: Zgc:92... 59 3e-07
UniRef50_Q29CY9 Cluster: GA17148-PA; n=1; Drosophila pseudoobscu... 58 5e-07
UniRef50_UPI00015A78D8 Cluster: UPI00015A78D8 related cluster; n... 58 7e-07
UniRef50_UPI0000E81009 Cluster: PREDICTED: similar to Transmembr... 56 2e-06
UniRef50_Q7T1T9 Cluster: Tmc6-related protein 2; n=3; Tetraodont... 56 4e-06
UniRef50_UPI0000D57404 Cluster: PREDICTED: similar to T13G4.3; n... 54 8e-06
UniRef50_UPI0000F1DB4A Cluster: PREDICTED: similar to Tmc6-relat... 52 5e-05
UniRef50_Q7Z014 Cluster: TmcB-like protein; n=3; Culicidae|Rep: ... 50 1e-04
UniRef50_Q7T1T8 Cluster: Tmc5 protein; n=3; Clupeocephala|Rep: T... 50 2e-04
UniRef50_Q61X36 Cluster: Putative uncharacterized protein CBG041... 50 2e-04
UniRef50_Q7Z403 Cluster: Transmembrane channel-like protein 6; n... 50 2e-04
UniRef50_UPI0001555930 Cluster: PREDICTED: similar to transmembr... 49 4e-04
UniRef50_Q4S7Q8 Cluster: Chromosome 18 SCAF14712, whole genome s... 49 4e-04
UniRef50_Q5YCC6 Cluster: Transmembrane channel-like 6; n=2; Amni... 48 6e-04
UniRef50_Q4TGL8 Cluster: Chromosome undetermined SCAF3617, whole... 47 0.001
UniRef50_UPI00015A3D40 Cluster: Transmembrane channel-like prote... 39 0.34
UniRef50_Q7K4K7 Cluster: LD35238p; n=2; Sophophora|Rep: LD35238p... 37 1.8
UniRef50_Q8IPP9 Cluster: CG31551-PA; n=2; Eukaryota|Rep: CG31551... 36 2.4
UniRef50_UPI0000ECA48E Cluster: Transmembrane channel-like prote... 36 3.2
UniRef50_A6GE67 Cluster: Putative uncharacterized protein; n=1; ... 36 3.2
UniRef50_Q4P7S2 Cluster: Putative uncharacterized protein; n=1; ... 36 3.2
UniRef50_UPI0000E0F4DE Cluster: dephospho-CoA kinase; n=1; alpha... 36 4.2
UniRef50_Q00WH9 Cluster: Chromosome 14 contig 1, DNA sequence; n... 36 4.2
UniRef50_Q5W6K5 Cluster: ABI3-interacting protein-related; n=3; ... 35 5.5
UniRef50_Q2V360 Cluster: Uncharacterized protein At5g20450.1; n=... 35 5.5
UniRef50_UPI0000ECA4D7 Cluster: Transmembrane channel-like prote... 35 7.3
UniRef50_Q4AAN6 Cluster: Putative uncharacterized protein; n=5; ... 35 7.3
UniRef50_Q0IN30 Cluster: Os12g0511100 protein; n=1; Oryza sativa... 35 7.3
UniRef50_A0EAM4 Cluster: Chromosome undetermined scaffold_86, wh... 35 7.3
UniRef50_UPI00006CB0B4 Cluster: hypothetical protein TTHERM_0024... 34 9.7
UniRef50_A0C7P7 Cluster: Chromosome undetermined scaffold_156, w... 34 9.7
UniRef50_A0BXU7 Cluster: Chromosome undetermined scaffold_135, w... 34 9.7
>UniRef50_UPI00015B631D Cluster: PREDICTED: similar to tmc7 protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to tmc7
protein - Nasonia vitripennis
Length = 775
Score = 483 bits (1190), Expect = e-135
Identities = 259/602 (43%), Positives = 358/602 (59%), Gaps = 32/602 (5%)
Query: 14 RHEGWEEAGGEFYQELYPGG--EQELFDNLQRADAAKLATLLPSKQAR-NTTTVKRARSQ 70
R +GWEEAG EFYQE YP E +L LQR D + +ATLLPSK++R TTT KR R +
Sbjct: 13 RGQGWEEAGAEFYQESYPAAAIEADLQQALQR-DPSHIATLLPSKKSRVATTTAKRVRHE 71
Query: 71 TD----RRQSTFARTMQS---------RDIHLSMLPDLSENLSNEERSWEEIMQIKALPV 117
RR ST +R S +D +SMLPDLSENLSNEER+WEEIMQIKA+PV
Sbjct: 72 PRTTLRRRTSTRSRCATSTARRMSTNVQDAAVSMLPDLSENLSNEERTWEEIMQIKAMPV 131
Query: 118 PMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEG 177
M+QKI+LK +LQ+ATKLRLQGF+QL ++RK W F I E +SK+ELW ++ I G
Sbjct: 132 CMAQKIQLKNQLQSATKLRLQGFDQLKWQRRKAWQTFSIRAKEAYSKMELWSMSLKRIGG 191
Query: 178 KFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTE-RVYECDETEANSTVCCSIA 236
FG G+V+Y + ++ VFLILP LL RV C T+CC
Sbjct: 192 NFGMGIVAYFLFIKWILFLNFILFAIIAVFLILPTILLAPMRVETCAYINNTDTICCPEL 251
Query: 237 YFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILV 296
Y K+ + FLD QG E ++LFYG Y+ +S Y Y++P+AYI V
Sbjct: 252 YRNKSKEHET-FLDFFQGNNLFEYSLLFYGAYSSSSIPSEEDSFY-----YDLPLAYICV 305
Query: 297 PISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALY 356
++ +SL+AIV++A +GF+++++E EGQFY+YCNLVFGGWD+CI+N++++ KH+ALY
Sbjct: 306 MMTIFAMSLVAIVRSAVKGFRERVVEGEGQFYRYCNLVFGGWDYCINNEKASETKHKALY 365
Query: 357 NEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERL 416
NEIK +E ER +EE+Q+R+RE + + L R + G I+ FS +++
Sbjct: 366 NEIKVLLESERFEEERQNRTREEKFKLCLVRVFVNALVLLILCSCGVFIFYIIRFSFDQV 425
Query: 417 NESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYM 476
GSN T ++ ++ + + EFLP+ICIV+LN+ +P +F ++I E Y
Sbjct: 426 YS--GSN----ATERPKFSELTMESVNQIFFEFLPYICIVLLNVTVPVLFRHLISLENYS 479
Query: 477 PPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLECWETYVGQQFY 536
PP Y+ I G V T++T+ CWET+VGQQF
Sbjct: 480 PPFVVKVTLFRTIFLRLASLAVLLSSFYMRIV--GSVDEDQCTNSTRPLCWETFVGQQFL 537
Query: 537 KLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMA 596
KL +TD QF TF +N PR+F+ +H+ S+ L+ G+QEF L KHVLDIVY+QTI W+
Sbjct: 538 KLYITDLVGQFFMTFFVNFPRSFIGKHSESKFLRFIGQQEFDLSKHVLDIVYLQTICWLG 597
Query: 597 MF 598
F
Sbjct: 598 AF 599
>UniRef50_UPI000051A81F Cluster: PREDICTED: similar to transmembrane
channel-like 7; n=1; Apis mellifera|Rep: PREDICTED:
similar to transmembrane channel-like 7 - Apis mellifera
Length = 756
Score = 469 bits (1156), Expect = e-130
Identities = 257/599 (42%), Positives = 352/599 (58%), Gaps = 49/599 (8%)
Query: 14 RHEGWEEAGGEFYQELYPGG-EQELFDNLQRADAAKLATLLPSKQAR---------NTTT 63
R +GWEEAG EFYQE YP E +L LQR D + +ATLLPSK++R +T T
Sbjct: 13 RGQGWEEAGAEFYQESYPAAIEADLQQALQR-DPSHIATLLPSKKSRVATGKRIRNDTKT 71
Query: 64 VKRARSQTDRRQSTFARTMQSR--DIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQ 121
R R+ T R +T +R M + D +SMLPDLSENLSNEER+WEEIMQIKA+P
Sbjct: 72 TLRRRTSTRSRGTTTSRRMSTNIHDAAVSMLPDLSENLSNEERTWEEIMQIKAMP----- 126
Query: 122 KIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGT 181
+ATKLRLQGFEQL ++RK W +FRI ET+SK+ELW ++ I G FG
Sbjct: 127 ---------SATKLRLQGFEQLKWQRRKAWQQFRIRMKETYSKMELWNDSLKTIGGNFGM 177
Query: 182 GVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLT--ERVYECDETEANSTVCCSIAYFE 239
G+V+Y + ++ F+ILP LL E + +NS CCS Y +
Sbjct: 178 GIVAYFLFIKWLMYLNVLLFTIMFSFIILPTILLDIPEEELCINSNNSNSISCCSELY-Q 236
Query: 240 KNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPIS 299
T SN D+ G +E T+LFYGVY+ Y + +F+N+P++YI I
Sbjct: 237 NITQESNSITDI----GILEYTLLFYGVYSHISYDT-------SGIFFNLPLSYISATIG 285
Query: 300 WTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEI 359
+LSLIAIVK+AA+ FKQ++IE+EGQFY+YCNL+FGGWD+CIHN++SA +KH+ALYNE+
Sbjct: 286 IFILSLIAIVKSAAKSFKQRVIENEGQFYQYCNLIFGGWDYCIHNEKSATVKHKALYNEM 345
Query: 360 KGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERLNES 419
K +E ER++EE+Q+R+RE + R G IY F FS ++++
Sbjct: 346 KAFLEAERLEEERQNRTREETTKLFFMRLFINLIVLTVLCGCGMFIYYIFEFSFDQISTQ 405
Query: 420 IGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPH 479
I +T + Y +S N++ ++ EFLP+ICIV LNL IP +F Y++ E Y P
Sbjct: 406 I------NQTYDLQY--LSLNRIAHLFFEFLPYICIVALNLAIPFLFRYLVSLENYSPSF 457
Query: 480 XXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLECWETYVGQQFYKLI 539
Y I T + NT + CWET+VGQQF+KL
Sbjct: 458 VINITLLRTVFLRLSSLIVLLTSFYRLIVTEVMDNECTNTANRRPLCWETFVGQQFFKLY 517
Query: 540 LTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+TD ++QF TF +N PR+ +A+HT ++ L+ FGEQEF L KHVLD+VY+QT+ W+ F
Sbjct: 518 ITDLSLQFFMTFFVNFPRSLIAKHTENKILRFFGEQEFDLSKHVLDVVYLQTVCWLGFF 576
>UniRef50_UPI0000D55B64 Cluster: PREDICTED: similar to transmembrane
channel-like 7; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to transmembrane channel-like 7 - Tribolium
castaneum
Length = 738
Score = 460 bits (1133), Expect = e-128
Identities = 250/595 (42%), Positives = 351/595 (58%), Gaps = 67/595 (11%)
Query: 16 EGWEEAGGEFYQELYPGGEQELFDNLQRADAAK-LATLLPSKQAR----------NTTTV 64
+GWEEAG EFYQE YP + EL D LQR K LATLLPSKQ R + T+
Sbjct: 14 QGWEEAGSEFYQESYPT-DAEL-DALQRDPNPKHLATLLPSKQTRAAATIRIRTNDNRTI 71
Query: 65 KRARSQTDRRQSTFARTMQSR-DIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKI 123
+R + RR ST R + D+ ++MLPDLSENLSNE+ +WEEIMQIK +PVPMSQK
Sbjct: 72 RRQTASRSRRDSTVHRRASTAGDVQVAMLPDLSENLSNEQTTWEEIMQIKGMPVPMSQKK 131
Query: 124 ELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGV 183
E+KA++ N LRLQG+EQL+ ++RK+W +F E +K+ELW++ ++ IEG FGTGV
Sbjct: 132 EMKAKILNEPNLRLQGYEQLNWKRRKIWRQFISRLKEMHTKIELWRSALKRIEGHFGTGV 191
Query: 184 VSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTT 243
V+Y I ++ +F+ILP LL NS +
Sbjct: 192 VAYFIFLKYLLFLNLFIFTVIFLFIILPTILL-----------VNSDT-------QNPPN 233
Query: 244 NSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLL 303
+SN+ D+IQGTG+ME ++LFYG Y ++ + Y VN + ++YN+P+AY+ + + +
Sbjct: 234 SSNVVFDLIQGTGFMEHSLLFYGFYPNETFDYLVN---ESVMYYNLPLAYVCITVVYFAT 290
Query: 304 SLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCI 363
SL+++VK+AA GFK++LIE EGQFY+YCN +FGGWDFCIHN++SA IKH+A+YNEIK C+
Sbjct: 291 SLVSMVKSAANGFKERLIEGEGQFYQYCNFIFGGWDFCIHNEKSAAIKHKAIYNEIKACL 350
Query: 364 EEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSN 423
ER++E KQ+R++ + + R A G I+ F E NES
Sbjct: 351 AAERLEEMKQNRTKGEHTKLIIVRILVNVIVLAVLGACGTAIFFVFQ---EFRNES---- 403
Query: 424 ENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXX 483
S + E +L +FLP I IV N+++P +F Y+I++E Y P
Sbjct: 404 --------------SDDYFEGLLFQFLPSITIVCFNILVPFLFKYLIQFERYSP------ 443
Query: 484 XXXXXXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLECWETYVGQQFYKLILTDF 543
LYI+ ++ T + K CWET+ GQQ YKL++TDF
Sbjct: 444 LVVVRFTLFRTVLLRLASIFTLYITLGSVL-----TSSEKPNCWETFAGQQIYKLVITDF 498
Query: 544 AVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
A + TFL+N PRAF+ARH ++ +K+ GEQ F LPKHVLD+VY+QT+ W+ F
Sbjct: 499 ATHVILTFLVNFPRAFIARHVENKFIKLVGEQSFDLPKHVLDVVYLQTLCWLGCF 553
>UniRef50_Q17MQ2 Cluster: Tmc7 protein; n=1; Aedes aegypti|Rep: Tmc7
protein - Aedes aegypti (Yellowfever mosquito)
Length = 932
Score = 353 bits (868), Expect = 8e-96
Identities = 193/436 (44%), Positives = 266/436 (61%), Gaps = 33/436 (7%)
Query: 16 EGWEEAGGEFYQELYPGGEQELFDNLQRADAAKLATLLPSKQARNTTTVKRARSQTD--- 72
+GWEEAGGEFYQE YP + +QR D +K+ATLLPSKQ RN TT + SQ D
Sbjct: 15 QGWEEAGGEFYQESYPAD----LEGMQR-DPSKIATLLPSKQTRNATTRRVRPSQQDTKG 69
Query: 73 -RRQSTFA----RTMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKIELKA 127
RR+++F+ R Q +I ++ LPDLSENL NEER+WEEI +IK++PVPM+QK E+KA
Sbjct: 70 TRRRTSFSTVARRGSQYHEIQVATLPDLSENLINEERTWEEIQEIKSMPVPMAQKREMKA 129
Query: 128 RLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYX 187
+LQNATKLRLQGFEQ+ R+RK W R +E SKLELW+ ++ IEG FGTGVV+Y
Sbjct: 130 QLQNATKLRLQGFEQIKWRRRKAWQSVRAKWSEYRSKLELWRMSLKTIEGNFGTGVVAYF 189
Query: 188 XXXXXXXXXXXTISILVIVFLILPKTLLTE-RVYECD-ETEANSTVCCSIAYFEKNTTNS 245
+ LV F++LP +L E + C+ + + S CCS +Y
Sbjct: 190 LFLRWLMFLNLIVFGLVSAFIVLPYVVLREPQDLPCEQQIDPRSVQCCSESYVNATKRVE 249
Query: 246 NIFLDVIQGTGWMERTILFYGVYTDQIYTY--YVNSLY----------------HTKLFY 287
LDVIQGTG+ME T+LFYG+YT+ IY Y Y L T L+Y
Sbjct: 250 FAVLDVIQGTGFMEGTLLFYGMYTNMIYGYSPYYEGLIMEMGEAIDQSAAEVSSGTVLYY 309
Query: 288 NMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRS 347
+ P+ Y+++ +++LIA++K R FK ++ E EG FY+YCNLVFGGWDFCIHN++S
Sbjct: 310 DFPLVYVIITAICYVVALIAMMKAVVRQFKDRIAEGEGLFYQYCNLVFGGWDFCIHNEKS 369
Query: 348 ARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYV 407
A IKH+ALY+EI+ + +R + E+ +RSR+ + + R + +IYV
Sbjct: 370 ADIKHKALYHEIRSLLHTKRFENERINRSRDFMVKLISIRFMINLIVFVILTIAVVIIYV 429
Query: 408 AFNFSTERLNESIGSN 423
FN S +L+ + +N
Sbjct: 430 LFNVSMSKLDPNFQNN 445
Score = 116 bits (280), Expect = 1e-24
Identities = 65/183 (35%), Positives = 90/183 (49%), Gaps = 25/183 (13%)
Query: 441 QLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXX 500
+LE + EFLP+I IV +NL++P F+Y++++E Y P
Sbjct: 505 RLEVLFYEFLPYIAIVCMNLVVPLFFNYLVQFEKYSPLFVIKITLFRTVFLRLSSLAVLL 564
Query: 501 XQIYLYIS---------TNGIVCAKH------NTDTTKLECW----------ETYVGQQF 535
+ Y + TNG + N T +C+ ET+VGQQF
Sbjct: 565 SRFYFLVKPKIHQTVLPTNGTDTMTNFTLEVVNGTTMTDQCYDMERGTPQCWETFVGQQF 624
Query: 536 YKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWM 595
YKL + DF F+ TF +N PRA ARH+ SR K GEQEF L KHVLD++Y QT+ W+
Sbjct: 625 YKLFMVDFVTHFLVTFFVNFPRAMFARHSNSRIAKFIGEQEFELSKHVLDVIYSQTLCWL 684
Query: 596 AMF 598
F
Sbjct: 685 GTF 687
>UniRef50_Q7Z402 Cluster: Transmembrane channel-like protein 7;
n=17; Euteleostomi|Rep: Transmembrane channel-like
protein 7 - Homo sapiens (Human)
Length = 723
Score = 231 bits (565), Expect = 4e-59
Identities = 161/544 (29%), Positives = 249/544 (45%), Gaps = 40/544 (7%)
Query: 63 TVKRARSQTDRRQSTFARTMQSRDIHLSMLPD-LSENLSNEERSWEEIMQIKALPVPMSQ 121
++ R R+ R ++ D + S L D ++ENLS+ ++ + +S+
Sbjct: 48 SIARRRTTVHSRDKQSGTLLKPTDSYSSQLEDRIAENLSSHS--------LRNYALNISE 99
Query: 122 KIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGT 181
K L+ +Q L ++Q K W RF E + LELW+ +R IEGKFGT
Sbjct: 100 KRRLRD-IQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGT 158
Query: 182 GVVSYXXXXXXXXXXXXTISILVIVFLILPKTL----LTERVYECDETEANSTVCCSIAY 237
G+ SY I +++ + ++LP L +T + + C
Sbjct: 159 GIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPV 218
Query: 238 FEKNTTNS-NIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILV 296
+ +D++ GTG++E T LFYG YT ++ + Y++P+AY+L
Sbjct: 219 SSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYT-------IDGVKFQNFTYDLPLAYLLS 271
Query: 297 PISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALY 356
I+ LSL+ IVK + GFK LI SE F YCN +F GWDFCI N A +KH +L
Sbjct: 272 TIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLR 331
Query: 357 NEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERL 416
E++ +EEER++++ R+ E I ++ R A + IYVA FS E +
Sbjct: 332 YELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHM 391
Query: 417 NESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYM 476
+ I M F EN+ + +LP I I + N I P IF+ +IRYE Y
Sbjct: 392 KKEIDK--------------MVFG--ENLFILYLPSIVITLANFITPMIFAKIIRYEDYS 435
Query: 477 PPHXXXXXXXXXXXXXXXXXXXXXXQIYLYI-STNGIVCAKHNTDTTKLECWETYVGQQF 535
P + I S + C + CWET VGQ+
Sbjct: 436 PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEM 495
Query: 536 YKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCLKMFGEQEFYLPKHVLDIVYVQTIIW 594
YKL++ DF + T ++ PR + + S + ++ +G+QEF +P +VL IVY QTI W
Sbjct: 496 YKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICW 555
Query: 595 MAMF 598
+ F
Sbjct: 556 IGAF 559
>UniRef50_Q5YCC5 Cluster: Transmembrane channel-like protein 7; n=9;
Deuterostomia|Rep: Transmembrane channel-like protein 7
- Gallus gallus (Chicken)
Length = 735
Score = 227 bits (555), Expect = 7e-58
Identities = 134/456 (29%), Positives = 218/456 (47%), Gaps = 29/456 (6%)
Query: 149 KVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFL 208
K W + E S ++LW+ + IEGKFGTG+ SY + IL+ F+
Sbjct: 120 KSWKKALKDIKELSSYMQLWRHDIHSIEGKFGTGIQSYFSFLRFLVLLNFLMFILMFSFV 179
Query: 209 ILPKTLLTERVYECDETEA--NSTVCCSIAYFEKNTTNSNIFL----DVIQGTGWMERTI 262
LP + ++ T+ N+T Y F D++ GTG++E T+
Sbjct: 180 TLPAVISNYGIFNSSSTKISPNNTEPYCTVYTPSGNKGLVYFYTYLKDLLTGTGFLEVTV 239
Query: 263 LFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIE 322
LFYG YT +++ + + L YN+P+AY+L ++ LS + I+K + F+Q L++
Sbjct: 240 LFYGYYT-------IDAAWFSVLRYNLPLAYLLTTFAYLALSFVWIIKRSVERFRQHLVD 292
Query: 323 SEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQIL 382
E QF YCN VF GWDFCI + +AR+KH++L E++ +EEER+K++ R+ + ++
Sbjct: 293 DEDQFQSYCNKVFAGWDFCITDLNAARLKHRSLLYELQTNLEEERLKQKIAERTMKEKLQ 352
Query: 383 MHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQL 442
++ R + IY A FS E + SI N +
Sbjct: 353 IYSLRIFINIIVIAVLSGCFYSIYRATVFSQENSSVSIRRNV----------------MI 396
Query: 443 ENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQ 502
N+L+++LP I I N I P+IFS++IR+E Y
Sbjct: 397 ANLLVQYLPSIVITSANFIAPQIFSFLIRFEDYSAAFEIRLTLIRCVFVRLANVGVLLFS 456
Query: 503 IYLYISTNGIVCAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMAR 562
++ I + C D CWE+ VGQ+ YKL++ DF + T ++ PR +
Sbjct: 457 LWSQIHCDNDQCKACGYDYELYPCWESAVGQEMYKLLIFDFMIIIAMTLFVDFPRKLLVT 516
Query: 563 HTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+ + ++ +G QEF + +VL+I+Y QTI W+ F
Sbjct: 517 YCSWKLVQWWGLQEFGISDNVLEIIYGQTICWIGTF 552
>UniRef50_A7RJT8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 612
Score = 196 bits (478), Expect = 1e-48
Identities = 139/493 (28%), Positives = 223/493 (45%), Gaps = 35/493 (7%)
Query: 107 EEIMQIKALPVPMSQKIELKARLQNATKLR-LQGFEQLHLRQRKVWHRFRIGCTETFSKL 165
E+ ++KA+ PM QK E+K K+R + ++ L+ WHR + L
Sbjct: 74 EDFQEVKAVAAPMQQKREMKKNQTAGQKIRRISCWKATKLKIAMGWHRLTGRIGDALRDL 133
Query: 166 ELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDET 225
ELW+ M+EIEG+FG GV+SY I +L F +P L++E V + T
Sbjct: 134 ELWKGSMKEIEGRFGNGVLSYFVFLKWLMFVNLFIFLLTFGFTSVP-ALVSEPVAAPNNT 192
Query: 226 EANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKL 285
NS + Y +K+ + + LD I G GW+ T+LFY Y + + L HT
Sbjct: 193 --NSCTYSTDTYTDKSPPD--LVLDFITGVGWINTTLLFYSSYPSETIK---SVLGHT-- 243
Query: 286 FYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHND 345
YN+P+AY+LV ++ SL+ +V + F++ IE G FY YCN F WD+CI ++
Sbjct: 244 -YNLPLAYLLVGGAYFFFSLLLMVNNLTKSFQESYIEGGGTFYSYCNKAFASWDYCIDDE 302
Query: 346 RSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLI 405
+AR+K Q + +IK + EE E+ ++R+R + ++ R + + I
Sbjct: 303 NTARVKSQNIVQDIKAGLAEEARLEKVRNRTRGQKCRLYTIRATCTLLVMGLLGGAVYAI 362
Query: 406 YVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEI 465
Y+A ST+ + E ++ M I+ + S + I LNL++P
Sbjct: 363 YLAVEVSTDPKVQ-----EGKSAFMVILIRSAS-------------SLTITGLNLLLPPF 404
Query: 466 FSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLE 525
F + +E + P +Y+ + G C +
Sbjct: 405 FILVSNFEDWSPRFQVNISLWRTVLLRLASIAVLIITLYVDV---GKKCDDGEKSCCQ-N 460
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLD 585
WE + Q Y LI DF V TT + + +HTR K+ EF +PK+VLD
Sbjct: 461 SWENQIASQMYMLIWIDFFVVIATTLGMETILRLLFKHTR-LFRKLNVMPEFQIPKNVLD 519
Query: 586 IVYVQTIIWMAMF 598
+VY Q ++W+ F
Sbjct: 520 LVYGQCLLWIGTF 532
>UniRef50_UPI00006A062E Cluster: transmembrane channel-like 4; n=1;
Xenopus tropicalis|Rep: transmembrane channel-like 4 -
Xenopus tropicalis
Length = 589
Score = 160 bits (388), Expect = 1e-37
Identities = 104/427 (24%), Positives = 191/427 (44%), Gaps = 29/427 (6%)
Query: 153 RFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPK 212
+F+ +E+ L LW+ + I G FGTG+ SY +L+ F+++P
Sbjct: 14 QFQSKASESLQFLVLWRRTINTIGGNFGTGIASYFTFLRFLILMNLVTFLLIGGFIVIPN 73
Query: 213 TLLTE-RVYECDETEANSTVCCSIAYFEKNTTNSNIFL-DVIQGTGWMERTILFYGVYTD 270
+ E V + ++ ++ +C + + F+ D++ GTG+ME T +FYG Y +
Sbjct: 74 IVFQELNVNQTSQSSNSNGLCLKYSPNPQGLERYYTFIMDILMGTGFMELTYMFYGFYKN 133
Query: 271 QIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKY 330
+ + +YN+P+AY+ + + LLSL+ IV + +GFKQ L+ Q Y
Sbjct: 134 TLVIL-------AEFYYNLPLAYLTTTLFYFLLSLVWIVVRSVKGFKQSLVTENTQLSNY 186
Query: 331 CNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXX 390
+ +F GWDFCI + R ++K +++ E++ +EEE +K + R+ + ++ R
Sbjct: 187 TSKIFVGWDFCIKDPRIVKLKQKSIRYELQMDLEEENMKRKHAERTTSQRATIYTLRVFF 246
Query: 391 XXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFL 450
A+ + IY++ S L S ++ N + ++++ +L
Sbjct: 247 NLVVICLTGAAFYCIYLSTVNSQVLLTNS----------------SVKENFILDLVVGYL 290
Query: 451 PFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTN 510
P I I N +P +F +I++E Y ++ I+ +
Sbjct: 291 PSIVITAANFFLPIVFGIIIQWEKYTLSWEIRLTLIRCVFLRLASLGMLLYSLWDKITCS 350
Query: 511 G----IVCAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRS 566
G C + + +CWET VGQ+ YKL++ DF V L++ PR ++
Sbjct: 351 GTPQDAQCVTCGYNIDQYKCWETRVGQEMYKLLIFDFLTVLVVILLVDFPRKYLDTLKLY 410
Query: 567 RCLKMFG 573
CL G
Sbjct: 411 SCLGSVG 417
>UniRef50_A7SUG1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 613
Score = 156 bits (379), Expect = 1e-36
Identities = 120/461 (26%), Positives = 196/461 (42%), Gaps = 40/461 (8%)
Query: 151 WHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLIL 210
W F G E +ELW+ ++++EG+FG+GVVSY I L F++L
Sbjct: 21 WRSFVTGLREWKYAMELWRGHLKQVEGQFGSGVVSYFSFLRWLLFLNLLIFALEFGFVVL 80
Query: 211 PKTLLTERVYECDETEANSTVCCSIAYFEKNTTNS--------NIFLDVIQGTGWMERTI 262
P ++ + E+ N+ CS Y + +TN N L G GW+ T+
Sbjct: 81 PTVVICTSWNQ--ESHMNNITGCS--YQKPVSTNQSLQLGDVPNAVLQFFTGQGWIGTTL 136
Query: 263 LFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIE 322
+FY Y + + + YN+P+AY+L +L ++ K IE
Sbjct: 137 MFYSNYPSK------RLISEEGVTYNLPLAYLLTGGCTLILCFFLMITNLMGNLKDSYIE 190
Query: 323 SEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQIL 382
SEG F Y N VF WD+CI + +AR KH+ + +I I EE+ K Q+R+R+ +
Sbjct: 191 SEGMFNSYANKVFAVWDYCISEEIAARHKHRIIVQDINSDIAEEQRKRRVQNRTRKQKCA 250
Query: 383 MHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQL 442
++ R F++ + F+ E L+ + N R + S+
Sbjct: 251 LYSSRIAVNFIVVPALWYVSFVVIIQAIFNPEDLDFTDKGQSNMERIL------ASYGS- 303
Query: 443 ENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQ 502
L + I + NL++P +F ++ +E +
Sbjct: 304 -----SLLIALAITIPNLLLPLLFEFLSIFEDWSA--EVELALNLWRRVFVKLPSVAALM 356
Query: 503 IYLYISTNGIVCAKHNTDTTKLE----CWETYVGQQFYKLILTDFAVQFVTTF-LINLPR 557
I LYI+ + K +LE CWE + Q Y L+ DF V +TT L L +
Sbjct: 357 ILLYINIDKKTKKKSRNQHYRLEACEQCWEDELAAQMYMLVWMDFFVVILTTLGLETLRK 416
Query: 558 AFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
F + + C + G Q+F +P++VLD+VY Q +I + F
Sbjct: 417 VF---YNKFSCFRRIGMQQFDIPRNVLDLVYGQCLILLGGF 454
>UniRef50_UPI000069E015 Cluster: Transmembrane channel-like protein
8 (Epidermodysplasia verruciformis protein 2).; n=5;
Xenopus tropicalis|Rep: Transmembrane channel-like
protein 8 (Epidermodysplasia verruciformis protein 2). -
Xenopus tropicalis
Length = 602
Score = 136 bits (328), Expect = 2e-30
Identities = 115/512 (22%), Positives = 208/512 (40%), Gaps = 51/512 (9%)
Query: 101 NEERSWEEIM--QIKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGC 158
N W I +++ + M +K L ++ + Q H + W + +
Sbjct: 11 NHHNRWSGIRSKELREHAMSMQEKRLLSREKRSTRNDSTTPWAQQHSHVKATWEKVQ--- 67
Query: 159 TETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTER 218
E S LW+ + I GKFG+G+ SY L +I+P L +
Sbjct: 68 -EVLSLCLLWERTLVRISGKFGSGICSYFLILRFLILLNILSLFLTSGLVIIPTMLSNDS 126
Query: 219 VYECDETEANSTVCCSIAYFEKNTTNS-----NIFLDVIQGTGWMERTILFYGVYTDQIY 273
+ + + + S + + S + L +I G +E ++LFYG Y
Sbjct: 127 LQSQEFSFVLGYLSSSKCFTHSTSAISLSLLYKLILYLIFTQGLLENSLLFYGYY----- 181
Query: 274 TYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNL 333
N + +N+ +AY+L P+ + L+ + +++ RG + + +
Sbjct: 182 ----NKVTVIGSSFNIRLAYLLTPLLFLLICGLYLLRCTIRGLTLRRVRKRDYRTRISTK 237
Query: 334 VFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXX 393
VF GWDFC+ + K Q L NEIK +EEE S + E + L+
Sbjct: 238 VFSGWDFCVQGADNCANKQQMLSNEIKSHLEEEHW----HSNTVEQPLCRRLRVLTIRVL 293
Query: 394 XXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFI 453
+ + +T +S G P+ N + ++++++L I
Sbjct: 294 LNCVSLTLMIGAFYGVHLATGVSQDSQGG--------PV-------NSVLDLMIQYLVPI 338
Query: 454 CIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIV 513
I +++LI+P +F++++R+EG+ P I+LY I+
Sbjct: 339 VISMVHLILPPLFAFLVRFEGHSP-----NTEVNLTLIRCLLLRLGTLAIFLYSLGQKIL 393
Query: 514 CAKHNTDTTK-------LECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRS 566
C + + K +CWET +GQ+FYKL + F + L+ LP MA +
Sbjct: 394 CLDQSESSCKTCSYNPNFQCWETTMGQEFYKLFIFHFLKMLMEFLLLQLPLRLMASCCQC 453
Query: 567 RCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+ +++F LP++VLD VY QT++W +F
Sbjct: 454 WLISWLNQEQFQLPQNVLDTVYGQTLVWGGLF 485
>UniRef50_Q7T1T6 Cluster: Tmc4 protein; n=4; Clupeocephala|Rep: Tmc4
protein - Fugu rubripes (Japanese pufferfish) (Takifugu
rubripes)
Length = 660
Score = 131 bits (317), Expect = 5e-29
Identities = 103/457 (22%), Positives = 188/457 (41%), Gaps = 41/457 (8%)
Query: 146 RQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVI 205
++ K+ + R G E W+ ++ I G FG GV S+ +L+
Sbjct: 90 KRTKLLRKLREGTREFLYLFSPWRKALQLIAGNFGGGVQSFFVLLRFLVLLNFFSFLLIA 149
Query: 206 VFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIF----LDVIQGTGWMERT 261
F+++P + + D + C+ + N F LDV+ GTG++E +
Sbjct: 150 GFVLVPSIVFSSE--GSDSVNVSGLGECTD--YNPNPQGLVPFYSYVLDVLLGTGFVELS 205
Query: 262 ILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLI 321
LFYG +Y N+L FYN+P+AYI + + LI IV + +
Sbjct: 206 YLFYG--------FYKNTLVQGTNFYNIPLAYIFTAVFYIAFCLICIVARLGTTARVVVA 257
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQI 381
G Y + F WD+ ++ ++K + + ++ +EEER+K++ + + + +I
Sbjct: 258 TGGGSSGNYSMIAFASWDYGSLGEKETKLKQKNILYRLQVDLEEERLKKQAAALTLKQKI 317
Query: 382 LMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQ 441
+++ R A+ I++A FS ER +
Sbjct: 318 ILYSLRVILFFLALGLIIAALVGIFMATQFSQERSGQ---------------------EG 356
Query: 442 LENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXX 501
+ +++++LP I I N ++P + + E Y P
Sbjct: 357 ILGLIIQYLPSIVITAGNFVVPMLCDQISLLERYSPSLTIILALMRAVFLRLFGLCVLLF 416
Query: 502 QIYLYISTNGIV----CAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPR 557
++ ++ +G C + CWET VGQ+ YKL + D V T L+ PR
Sbjct: 417 TLWSQVTCSGNPEEDDCRLCQYNHKLYPCWETRVGQEMYKLTVFDLLVTIATLVLVEFPR 476
Query: 558 AFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIW 594
+ + ++ ++ G QEF +P +VL +VY QT++W
Sbjct: 477 RMLVDNWSNKLVQKLGRQEFVVPANVLVLVYGQTVVW 513
>UniRef50_Q7Z013 Cluster: TmcC-like protein; n=2; Anopheles
gambiae|Rep: TmcC-like protein - Anopheles gambiae
(African malaria mosquito)
Length = 699
Score = 128 bits (310), Expect = 3e-28
Identities = 56/134 (41%), Positives = 85/134 (63%)
Query: 283 TKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCI 342
T L+Y++P+ Y+++ + +++L+AI++ R FK ++ E EG FY+YCNLVFGGWDFCI
Sbjct: 44 TILYYDLPLVYVIIIAIYYIITLVAIMRAVVRQFKDRIAEGEGLFYQYCNLVFGGWDFCI 103
Query: 343 HNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASG 402
HN +SA IKH+AL+NEIK + ++R + E+ +RSRE + + R +
Sbjct: 104 HNQKSADIKHRALHNEIKSLLYQKRFEHERNNRSREFMLKLIAIRMLVNLVVFVILLLAA 163
Query: 403 FLIYVAFNFSTERL 416
IYV FN S L
Sbjct: 164 ITIYVLFNVSLAEL 177
Score = 109 bits (262), Expect = 2e-22
Identities = 44/74 (59%), Positives = 54/74 (72%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWET+VGQQFYKL + DFA F+ TF +N PRA ARH+ SR K GEQEF L KHVL
Sbjct: 384 QCWETFVGQQFYKLFIVDFATHFLVTFFVNFPRALFARHSSSRLAKFIGEQEFELSKHVL 443
Query: 585 DIVYVQTIIWMAMF 598
D++Y QT+ W+ F
Sbjct: 444 DVIYSQTLCWLGTF 457
Score = 47.6 bits (108), Expect = 0.001
Identities = 16/37 (43%), Positives = 29/37 (78%)
Query: 441 QLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMP 477
+L + EFLP++ IV +NL++P++F+Y+++YE Y P
Sbjct: 260 KLRVLFYEFLPYLAIVCMNLVVPQLFNYLVQYEKYSP 296
>UniRef50_Q8IU68 Cluster: Transmembrane channel-like protein 8;
n=16; Theria|Rep: Transmembrane channel-like protein 8 -
Homo sapiens (Human)
Length = 726
Score = 128 bits (310), Expect = 3e-28
Identities = 119/492 (24%), Positives = 193/492 (39%), Gaps = 42/492 (8%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LP M K L +L+ ++ +++ R++ V R R L LW+
Sbjct: 36 VRGLPYAMMDK-RLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA 94
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ EI G FGTG+ SY +L F++LP L R + T +
Sbjct: 95 LYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWL--RPPDPGPTLNLTLQ 152
Query: 232 CCSIAYFEKNTTN-SNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMP 290
C N V+ G + T LFYG Y V + Y++
Sbjct: 153 CPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYR-------VGP--ESSSVYSIR 202
Query: 291 MAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARI 350
+AY+L P++ LL ++ +G QK + +G VF WDFCI +A I
Sbjct: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262
Query: 351 KHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFN 410
K + NE K +EE R + Q ++R L + I+ A
Sbjct: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322
Query: 411 FSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMI 470
+S + ES+ +L+++LP I ++N + P +F++++
Sbjct: 323 YSQDNKEESLF-----------------------LLLQYLPPGVIALVNFLGPLLFTFLV 359
Query: 471 RYEGYMPPHXXXXXXXX----XXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLEC 526
+ E Y PP+ Q L I + C + + +C
Sbjct: 360 QLENY-PPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQC 418
Query: 527 WETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDI 586
WE VG++ YKL + +F + FL+ LPR + R +EF +PK+VLDI
Sbjct: 419 WENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDI 478
Query: 587 VYVQTIIWMAMF 598
V QT+ WM +F
Sbjct: 479 VAGQTVTWMGLF 490
>UniRef50_UPI00015A529C Cluster: UPI00015A529C related cluster; n=1;
Danio rerio|Rep: UPI00015A529C UniRef100 entry - Danio
rerio
Length = 602
Score = 120 bits (288), Expect = 1e-25
Identities = 112/489 (22%), Positives = 208/489 (42%), Gaps = 43/489 (8%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LPV + K +++ R Q+ K + ++ Q+ R + S L W+
Sbjct: 2 LRNLPVCLQDKRDIRDR-QHLQKRSIGSWDAWRRSQQTTRRRLKEQVGRAVSGLLPWRHM 60
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ IEG+FG GV +Y +++ +++P TL VY + TE +
Sbjct: 61 IHRIEGQFGVGVKAYFVFLRYLLGLNLLYCVIIGGSVLVP-TL----VYRGESTETQNPD 115
Query: 232 CCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPM 291
S+ ++ +++S + QG +E++ +F+ YT SL L N P+
Sbjct: 116 WSSL--YKDISSSSPLLCVCFQGV--LEKSAVFHSFYTR-------GSLDGACL--NTPL 162
Query: 292 AYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIK 351
++L +S LS+I +V+ G+K I + VF GWDF I + ++A +K
Sbjct: 163 LFLLGMVSIIFLSIIMLVRRTVVGYKHSWITGKHFSSNLSYKVFSGWDFSIQSPQAASLK 222
Query: 352 HQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNF 411
NE+K +EE+ + R+ + + L R S LIY A +
Sbjct: 223 QNFTRNELKMDLEEQAFHARVKQRTLTQWVRLVLFRILLNLAVLFLLTGSFVLIYYAIH- 281
Query: 412 STERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIR 471
L +S+ ++ + E V++++LP I + ++N+ +P IF+ +
Sbjct: 282 ----LQQSVHIHD------------CTDESTECVMLKYLPPITMTLINIALPRIFTKISE 325
Query: 472 YEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIVC-AKHNTDTTKLECWETY 530
+E Y IYL+ VC ++ +C E
Sbjct: 326 FEDY-----SLTIQLNLTLIRSIFLKLASLSIYLFFFIFSYVCICSSSSCLCVYQCEENE 380
Query: 531 VGQQFYKLILTDFAVQFVTTFLINLPRAFMA-RHTRSRCLKMFGEQEFYLPKHVLDIVYV 589
G++ YKL + + F + F + PR F+ + SR ++ G +F + +VLD+V
Sbjct: 381 FGKEMYKLTIFNLLEGFFSAFCVAYPRTFLVEKFPSSRLAQILGNNQFEITLNVLDLVNS 440
Query: 590 QTIIWMAMF 598
QT++W+ +F
Sbjct: 441 QTVMWVGVF 449
>UniRef50_UPI000155461D Cluster: PREDICTED: similar to EGDC3042;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
EGDC3042 - Ornithorhynchus anatinus
Length = 962
Score = 116 bits (279), Expect = 2e-24
Identities = 112/452 (24%), Positives = 202/452 (44%), Gaps = 77/452 (17%)
Query: 151 WHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLIL 210
+ RF+ +E F L+LWQ ++ I G+FGT ++SY I+ F+ +
Sbjct: 242 FRRFKSTLSEFFLSLQLWQKTLKVIGGQFGTSILSYFSFLKWLLKFNIFSFIVNFSFITI 301
Query: 211 PKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTD 270
P +C +++ N+ L+++ G G+ + T+++YG YT+
Sbjct: 302 P---------QCVDSKPNNLPFTG--------------LELLTGAGYFQETVMYYGFYTN 338
Query: 271 QIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKY 330
T NS LFYNM +AYI + ++ ++V + A+ F+ I + + +
Sbjct: 339 STITNESNS-----LFYNMQLAYIFTIGVYFMICFFSLVFSMAKSFRNNFI-NPYSYTRG 392
Query: 331 CNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEE-RIKEEKQSRSRESQILMHLKRXX 389
+ + WDF I ND++ ++K + L +IK + E + + + + R Q+ +HL
Sbjct: 393 ASRILCSWDFNITNDKAVQLKQKNLSTQIKENLSERLQDRVKLPLKKRMVQVGIHL---- 448
Query: 390 XXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEF 449
A+ I V + L+ES + T + NQ +L
Sbjct: 449 -GAWVLSTGTAAACCIGVYY------LSES-----------NFKFLTDTNNQAATLL--- 487
Query: 450 LPFICIVVLNLIIPEIFSYMIRYEGY-MPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYIS 508
LPF+ + +N I+P +S+ E + +P H I+L IS
Sbjct: 488 LPFV-VCCINFIVPLFYSFFGLVEKFDLPRH--------------QVYVIVIRNIFLKIS 532
Query: 509 TNGIVCAKHNTDTTKL--ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRS 566
GI+ + K+ +CWET +GQ Y+L+L D FV + L +L ++ R +
Sbjct: 533 IIGILSYYWLSMVAKMKEKCWETIIGQDIYRLLLMD----FVFSLLDSLVGEYVRRMVGT 588
Query: 567 RCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+K G EF + ++VLD++Y QT++W+ +F
Sbjct: 589 HLIKRLGVPEFDIARNVLDLIYTQTLVWIGLF 620
>UniRef50_Q7Z404 Cluster: Transmembrane channel-like protein 4;
n=22; Mammalia|Rep: Transmembrane channel-like protein 4
- Homo sapiens (Human)
Length = 706
Score = 115 bits (276), Expect = 4e-24
Identities = 102/457 (22%), Positives = 177/457 (38%), Gaps = 36/457 (7%)
Query: 146 RQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVI 205
R ++ R + E L+ W ++ I G+FG G SY S+L+
Sbjct: 117 RWARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMA 176
Query: 206 VFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFY 265
+LP T L + +S + + T + +++ G G++E + LFY
Sbjct: 177 CMTLLP-TWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFY 235
Query: 266 GVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEG 325
G Y + + + Y+ + L+ L+ I+ + G KQ L+
Sbjct: 236 GFYPPRP---------------RLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESE 280
Query: 326 QFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
Y + VF WDF + D R++ + + E++ +EE ++ + R+ Q + L
Sbjct: 281 ALTSYSHRVFSAWDFGLCGDVHVRLRQRIILYELQVELEETVVRRQAAVRTLGQQARVWL 340
Query: 386 KRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENV 445
R A+ + +Y A + E L E MP+V L +
Sbjct: 341 VRVLLNLLVVALLGAAFYGVYWATGCTVE-LQE-----------MPLVQEL----PLLKL 384
Query: 446 LMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYL 505
+ +LP I I +N ++P +F + EGY ++
Sbjct: 385 GVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFLRLASLVVLLFSLWN 444
Query: 506 YISTNGIV----CAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMA 561
I+ G C + +L CWET +GQ+ YKL+L D LI PR +
Sbjct: 445 QITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLC 504
Query: 562 RHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
++ G QEF +P VL ++Y QT++W+ F
Sbjct: 505 GLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSF 541
>UniRef50_UPI0000E48F40 Cluster: PREDICTED: similar to Tmc5 protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Tmc5 protein - Strongylocentrotus purpuratus
Length = 885
Score = 108 bits (260), Expect = 4e-22
Identities = 91/407 (22%), Positives = 171/407 (42%), Gaps = 56/407 (13%)
Query: 151 WHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLIL 210
W F ++ LELW++ +++IEG FG+GV SY + +L F+
Sbjct: 269 WESFLESLSDFTYSLELWRSSIKKIEGNFGSGVTSYFLLLKWLLLLNIPVFLLTFGFVTT 328
Query: 211 PKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTD 270
P+ +Y+ + +S +N + D++ G GW + T L+ G YT+
Sbjct: 329 PQL-----IYQPSASVPHS----------QNFSG----WDLLTGGGWFKDTELYCGYYTN 369
Query: 271 QIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKY 330
+ +T K +Y+MP+AY++ I +L LI I + +R ++Q + + + +
Sbjct: 370 ETFTV------DNKNYYSMPLAYLITNILIFILILIVIAQGMSRAYRQYFVTGDRHYNFF 423
Query: 331 CNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXX 390
VF GWD+ I ++ +A++K++++Y E+ + S ++L R
Sbjct: 424 TAKVFCGWDYSITSESTAKLKNKSIYLELAEALTSH---HSSDSIGCCKTFGIYLLRLTI 480
Query: 391 XXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFL 450
+ +LI+ ++ ++ G R +P+V + +N
Sbjct: 481 NIIVFAIIAGASYLIHYMYDSVVAEIDS--GLTVIRELAIPLVIS--GYN---------- 526
Query: 451 PFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTN 510
L +P +FS + +E Y P + Y N
Sbjct: 527 ---------LTLPYMFSVLSSFEKYSNPRMQLYVSLFRTFLMKASVLC----VLCYFWLN 573
Query: 511 GIVCAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPR 557
I C +T +ECWET++G + YKL++ DF +Q + TF++ R
Sbjct: 574 QISCTDESTQNC-VECWETFIGNEVYKLVIVDFILQSLATFVLEFIR 619
>UniRef50_Q4S012 Cluster: Chromosome 18 SCAF14786, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 18
SCAF14786, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 358
Score = 103 bits (248), Expect = 1e-20
Identities = 78/312 (25%), Positives = 131/312 (41%), Gaps = 32/312 (10%)
Query: 288 NMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRS 347
NMP+ Y+ +S LLS I +V+ G+K + + +F GWDF I + S
Sbjct: 17 NMPLLYLAGILSILLLSFILVVRRTIVGYKHTWMLRKRYNMNVSYKIFCGWDFTIQDSDS 76
Query: 348 ARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYV 407
A +K + N++K +EE+R R ++ ++L R + +LI+
Sbjct: 77 ASLKRGCIRNDLKLLLEEQRFSMRVAQRKLGQKVRLYLLRFFLNVLVLSLLGGAFYLIFF 136
Query: 408 AFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFS 467
A N S ++ ++ + ++ E+LP + I +NL++P IF
Sbjct: 137 AINTSMKKT---------------------AYQGVIKLVFEYLPPVTITFVNLLLPHIFR 175
Query: 468 YMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLECW 527
+ +E Y IYL T A +C
Sbjct: 176 KISTFEDY-----SFTMQINSTLVRSIFLKLASLGIYLMGET-----ALRAHVLLPFQCR 225
Query: 528 ETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCL-KMFGEQEFYLPKHVLDI 586
E +G++ YKL + +F FL N PR F+ S L ++ G+Q F +P +VLD+
Sbjct: 226 ENRLGKEMYKLSIFNFLATICNAFLFNFPRKFLQEACPSSLLARLSGQQRFLIPFNVLDL 285
Query: 587 VYVQTIIWMAMF 598
VY QT+ WM ++
Sbjct: 286 VYGQTVSWMGVY 297
>UniRef50_UPI0000E2410B Cluster: PREDICTED: transmembrane
channel-like 5 isoform 2; n=2; Eutheria|Rep: PREDICTED:
transmembrane channel-like 5 isoform 2 - Pan troglodytes
Length = 949
Score = 100 bits (240), Expect = 1e-19
Identities = 112/455 (24%), Positives = 189/455 (41%), Gaps = 79/455 (17%)
Query: 149 KVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFL 208
+ + R + +E + + LWQ ++ I GKFGT V+SY IL F+
Sbjct: 413 RAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFI 472
Query: 209 ILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVY 268
I+P+ + E KNT L+ G G+ T+++YG Y
Sbjct: 473 IIPQFTVAE----------------------KNTLQFT-GLEFFTGVGYFRDTVMYYGFY 509
Query: 269 TDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFY 328
T+ + ++ YNM +AYI + +++ + A+ F+ I
Sbjct: 510 TNSTIQHG-----NSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSG 564
Query: 329 KYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRX 388
L+F WDF + +++ ++K + L EI+ + E R ++ S+ +Q+L
Sbjct: 565 GITKLIFC-WDFTVTQEKAVKLKQKNLSTEIRENLSELR---QENSKLTFNQLLTRFSAY 620
Query: 389 XXX-XXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLM 447
A +Y ++ E L +T + P VL+
Sbjct: 621 MVAWVVSTGVAIACCAAVYYLAEYNLEFL---------KTHSNPGA-----------VLL 660
Query: 448 EFLPFICIVVLNLIIPEIFSYMIRYEGY-MPPHXXXXXXXXXXXXXXXXXXXXXXQIYLY 506
LPF+ + +NL +P I+S E Y MP H I+L
Sbjct: 661 --LPFV-VSCINLAVPCIYSTFRLVERYEMPRHEVYVLLIR--------------NIFLE 703
Query: 507 ISTNGIVCAKHNTDTTKL---ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARH 563
IS GI+C + +T L ECWET +GQ Y+L+L DF V +FL F+ R
Sbjct: 704 ISIIGILCY-YWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFL----GEFLRRI 758
Query: 564 TRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+ + G QEF + ++VL+++Y QT++W+ +F
Sbjct: 759 IGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIF 793
>UniRef50_Q6UXY8 Cluster: Transmembrane channel-like protein 5;
n=22; Amniota|Rep: Transmembrane channel-like protein 5
- Homo sapiens (Human)
Length = 1006
Score = 99 bits (238), Expect = 2e-19
Identities = 111/455 (24%), Positives = 190/455 (41%), Gaps = 79/455 (17%)
Query: 149 KVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFL 208
+ + R + +E + + LWQ ++ I GKFGT V+SY IL F+
Sbjct: 412 RAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFI 471
Query: 209 ILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVY 268
I+P+ + + KNT L+ G G+ T+++YG Y
Sbjct: 472 IIPQFTVAK----------------------KNTLQFT-GLEFFTGVGYFRDTVMYYGFY 508
Query: 269 TDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFY 328
T+ + ++ YNM +AYI + +++ + A+ F+ I
Sbjct: 509 TNSTIQHG-----NSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSG 563
Query: 329 KYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRX 388
L+F WDF + ++++ ++K + L EI+ + E R ++ S+ +Q+L
Sbjct: 564 GITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSELR---QENSKLTFNQLLTRFSAY 619
Query: 389 XXX-XXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLM 447
A +Y ++ E L +T + P VL+
Sbjct: 620 MVAWVVSTGVAIACCAAVYYLAEYNLEFL---------KTHSNPGA-----------VLL 659
Query: 448 EFLPFICIVVLNLIIPEIFSYMIRYEGY-MPPHXXXXXXXXXXXXXXXXXXXXXXQIYLY 506
LPF+ + +NL +P I+S E Y MP H I+L
Sbjct: 660 --LPFV-VSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIR--------------NIFLK 702
Query: 507 ISTNGIVCAKHNTDTTKL---ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARH 563
IS GI+C + +T L ECWET +GQ Y+L+L DF V +FL F+ R
Sbjct: 703 ISIIGILCY-YWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFL----GEFLRRI 757
Query: 564 TRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+ + G QEF + ++VL+++Y QT++W+ +F
Sbjct: 758 IGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIF 792
>UniRef50_UPI0000F20C6E Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 725
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/211 (30%), Positives = 105/211 (49%), Gaps = 17/211 (8%)
Query: 105 SWEEIMQIKALPVPMSQKI-ELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFS 163
S EE+ ++ LP+ M +K E + RLQ L G+ + R+ R + E +
Sbjct: 210 SGEELRPVRELPMSMQEKRREQQQRLQQGGAL--SGWGVWSVSVRRSLKRMKEDGAEALA 267
Query: 164 KLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECD 223
L+LW+ + IEG FGTG++SY + +L+ VF++LP + + +
Sbjct: 268 ALQLWRADIHLIEGMFGTGILSYFSFLRFVVLLNFVMFLLMFVFVMLPMIISSRTAHNTT 327
Query: 224 ETEANSTVCCSIAYFEKNTTNSNIF----LDVIQGTGWMERTILFYGVYTDQIYTYYVNS 279
++ N + C Y + + +F D++ GTG++ERT LFYG +Y
Sbjct: 328 DSRTNVSECS--VYPDTSRQGLVVFHEHITDLLSGTGFLERTYLFYG--------FYKPE 377
Query: 280 LYHTKLFYNMPMAYILVPISWTLLSLIAIVK 310
H + YN+P+AY+L I + LLSL+ IVK
Sbjct: 378 FIHPRFTYNLPLAYLLSTICYLLLSLVWIVK 408
Score = 76.2 bits (179), Expect = 2e-12
Identities = 30/73 (41%), Positives = 46/73 (63%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLD 585
CWET+VGQ+ YKL++ D + T + PR + +H R + G+QEF +P++VL+
Sbjct: 462 CWETHVGQEMYKLVIFDLLIVAAVTVFVEFPRKMVVQHWRCGVTQWLGQQEFSVPQNVLE 521
Query: 586 IVYVQTIIWMAMF 598
+VY QTI W+ F
Sbjct: 522 MVYGQTICWIGAF 534
>UniRef50_A7RLV1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 420
Score = 97.1 bits (231), Expect = 1e-18
Identities = 62/269 (23%), Positives = 112/269 (41%), Gaps = 17/269 (6%)
Query: 330 YCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXX 389
Y N VFG WD CI +D++A +K + E++ + E+ R+R + + R
Sbjct: 1 YSNKVFGSWDMCIVDDQAAELKMRTFLMEVEADLAEDLRLASLAKRTRLEKCQTYSIRAL 60
Query: 390 XXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEF 449
+G++IY A S + ++ +N+ ++ +L +
Sbjct: 61 INLVVIGLSAVAGYVIYEAAQLSLKSSSQLSPTNQK---------------EMIELLKGY 105
Query: 450 LPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYIST 509
+ + +LN ++P +F Y+ E + P I L+
Sbjct: 106 ASSLTLSILNAVLPALFFYLAHLEDWNP-RVRINILVLFRTVLLKLASVAVLMISLFEKI 164
Query: 510 NGIVCAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCL 569
N C + +D K CWE + + YKLI DF + + L + PR + A H
Sbjct: 165 NTDKCIVYPSDI-KWSCWENAIAAEMYKLIWMDFIMSVLVVLLFHTPRRYAADHLGKGIG 223
Query: 570 KMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+ G F +P++VL++VY Q +IW+ M+
Sbjct: 224 QKIGRPVFSIPQNVLELVYAQCLIWIGMW 252
>UniRef50_UPI00015B58C9 Cluster: PREDICTED: similar to tmc6 protein
(evin); n=1; Nasonia vitripennis|Rep: PREDICTED: similar
to tmc6 protein (evin) - Nasonia vitripennis
Length = 741
Score = 95.1 bits (226), Expect = 5e-18
Identities = 119/539 (22%), Positives = 219/539 (40%), Gaps = 83/539 (15%)
Query: 62 TTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIMQI-KALPVPMS 120
TT++ ARS + + A T+ + H+ + LS E E I + + L + S
Sbjct: 87 TTLRMARSTAEAMEEQ-AETIAN---HIQRKNKQDDPLS-ELAKLEMIRDMSQCLTLKRS 141
Query: 121 QKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFG 180
K ++ + + + + ++ L + + +I + S +ELW P++ IEG FG
Sbjct: 142 VKAKIISESLKSKRRPIGYWKNLRYKMSMTISKMKIAFRQFGSSIELWYHPIKTIEGHFG 201
Query: 181 TGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTVCCSIAYFEK 240
+G+ +Y + I F+ LP+ L+ E
Sbjct: 202 SGIATYFKFLRWLFIMNTVGCVFSICFVTLPQVLVQSHQIE------------------- 242
Query: 241 NTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISW 300
T +S D++ G G +I +YG YT+ T ++S ++ Y+MP AY L +
Sbjct: 243 -TFSS---WDLLLGNGLFTNSIFYYGFYTND--TLMLDS----EVAYDMPSAYFLTFVFC 292
Query: 301 TLLSLIAIVKTAARGFKQKLIE-SEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEI 359
+ I + AR +K+ IE S G +Y N +F WD+ I + ++A ++ ++Y E+
Sbjct: 293 YTFTFILLCFKVARSYKKCYIETSSGANNRYANKIFCSWDWGISSQKAASLRSASIYREL 352
Query: 360 KGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERLNES 419
+ + + K + S ++I HL R +G L+++ N +E+
Sbjct: 353 EELLWDS--KNLVTTSSCCTRIWTHLIRITMTTLILAVMCGTGVLLWLLLN-----EHEA 405
Query: 420 IGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPH 479
+ T+P+V T IV IP + S+ ++YE Y
Sbjct: 406 DETKVVSVLTVPVVIT------------------AIVT---FIPPLMSWSVKYEKYAKDR 444
Query: 480 XXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLECWETYVGQQFYKLI 539
+L T GI + CW+T + Q+ Y+L+
Sbjct: 445 VAFYITMIRVYIIAVIAVATLLTFWL---TRGI----------QAGCWQTRLAQEIYRLV 491
Query: 540 LTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
L D V FL+ + RA ++ R R FG F + ++ L+++Y Q++ W+ +
Sbjct: 492 LLDLFVSVFGMFLVQVIRA--SKPLRER----FGAPTFDIARNTLNLIYNQSLFWLVHY 544
>UniRef50_UPI0000D56BEC Cluster: PREDICTED: similar to transmembrane
channel-like gene family 5 (predicted); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to transmembrane
channel-like gene family 5 (predicted) - Tribolium
castaneum
Length = 382
Score = 94.3 bits (224), Expect = 9e-18
Identities = 65/254 (25%), Positives = 128/254 (50%), Gaps = 25/254 (9%)
Query: 122 KIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGT 181
K +L + +K R GF + + + + + + F+ ELW +++IEG+FG+
Sbjct: 6 KEKLTKSVSLKSKRRPIGFWKRFKYKSSIRFKKFVANVKNFNYFELWHGSLKDIEGRFGS 65
Query: 182 GVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTVCCSIAYFEKN 241
G SY +++ L++P+ + D TE N++ +I F+
Sbjct: 66 GYASYFKFLRWLFVMNFFVALFSFPLLVVPQIIY-------DATENNNS---NIRQFQA- 114
Query: 242 TTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWT 301
S+IF+ G G+ + T+L+YG YT+ +T + S L +++P+AY + +
Sbjct: 115 ---SDIFI----GNGFFDDTVLYYGHYTN--HTIQLISF----LLFDVPVAYFTLIVVLY 161
Query: 302 LLSLIAIVKTAARGFKQKLIESEGQFYK-YCNLVFGGWDFCIHNDRSARIKHQALYNEIK 360
L+S + + + A+ +++ IE++G + N +F GWD+ I +A +K A++NE+K
Sbjct: 162 LISFVILAVSVAQSYRRTFIETKGGLQNVFANRIFCGWDYSIATKEAAHLKSLAIFNELK 221
Query: 361 GCIEEERIKEEKQS 374
+ EER +E ++
Sbjct: 222 ELLNEERRYDEDRT 235
Score = 41.9 bits (94), Expect = 0.048
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 12/117 (10%)
Query: 438 SFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXX 497
++ Q +N + + I I V+ +++P +F Y+ YE Y P
Sbjct: 270 NYGQEDNAKV-LITTIVINVILMVLPSVFHYVATYEDYANPRTALYITLIRTYLLGSVII 328
Query: 498 XXXXQIYLYISTNGIVCAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLIN 554
+L N+ T +CWE ++G + Y+ +L DF V T +I+
Sbjct: 329 GTVLSFWLI-----------NSGNTVHDCWENHLGAEIYRFVLFDFIFSVVLTTVID 374
>UniRef50_Q7Z5M5 Cluster: Transmembrane channel-like protein 3;
n=30; Euteleostomi|Rep: Transmembrane channel-like
protein 3 - Homo sapiens (Human)
Length = 1102
Score = 82.2 bits (194), Expect = 4e-14
Identities = 68/279 (24%), Positives = 124/279 (44%), Gaps = 27/279 (9%)
Query: 112 IKALPVPMSQKIELKARLQNAT---KLRLQGFEQLHLRQRKVWHRF-RIGCTETFSKLEL 167
I+ P M QK+ + +N + RL ++W +F R+ C +
Sbjct: 63 IRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIFIP- 121
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ +++IE FG+GV SY ++I+ F+++P+ + + + A
Sbjct: 122 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPEVIAGQPF----GSTA 177
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTG-WMERTILFYGVYTDQIYTYYVNSLYHTKLF 286
T+ K +S LD + G +++ ++LFYG YY +
Sbjct: 178 RKTI-------PKEQVSSAQDLDTVWSLGGYLQYSVLFYG--------YYGRERKIGRAG 222
Query: 287 YNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDR 346
Y +P+AY LV ++ S I ++K A+ + L + + Y +C VF WD+ I N
Sbjct: 223 YRLPLAYFLVGMAVFAYSFIILLKRMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPE 282
Query: 347 SARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
+A K A+ N I+ I EE +E+K+S++ I + +
Sbjct: 283 AAESKTAAIVNSIREAILEE--QEKKKSKNLAVTICLRI 319
Score = 51.6 bits (118), Expect = 6e-05
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 518 NTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSR-CLKM---FG 573
+T + + +CWETYVGQ+ KL + D + LI+ R R+ C + F
Sbjct: 490 HTQSPQDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFP 549
Query: 574 EQ-EFYLPKHVLDIVYVQTIIWMAMF 598
E EF + ++VL +VY Q +IWM F
Sbjct: 550 EYGEFKIAENVLHLVYNQGMIWMGAF 575
>UniRef50_Q4S011 Cluster: Chromosome 18 SCAF14786, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 18
SCAF14786, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 854
Score = 77.8 bits (183), Expect = 8e-13
Identities = 92/439 (20%), Positives = 168/439 (38%), Gaps = 55/439 (12%)
Query: 165 LELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDE 224
L+LWQ ++ + G+FGTGV+SY + ++ FL+LP+ L
Sbjct: 222 LQLWQVALKRVSGRFGTGVLSYFVFIKTLLLFNAFLCLVTGAFLVLPQVLFPPVPAAGRP 281
Query: 225 TEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTK 284
+ YF + + T + + + T S T+
Sbjct: 282 PFCGLELLTGAGYFTDTVMYYGYYANYTLQTSCGDEDDGHHNASLSKNATLECTS---TQ 338
Query: 285 LFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHN 344
L YNMP+AY ++ I +V + ++ F + E VF WDF +
Sbjct: 339 LSYNMPLAYFFTIGVAFFITCIILVYSMSKSFGRSF-RIEKSHGILAMKVFCSWDFKVIR 397
Query: 345 DRSARIKHQALYNEIKGCIEEERIKEEKQSRSRES-QILMHLKRXXXXXXXXXXXXASGF 403
+ S RI + + ++K + E K++ + ++ ++ +H AS F
Sbjct: 398 ETSVRIMSENICTQLKELLTEVGHKDDDTTLGQQLWRVAVH---ALAWTICIGSTAASVF 454
Query: 404 LIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIP 463
IY FS E + L M LP + + ++NL++P
Sbjct: 455 SIY---QFSEYMHGEPL---------------------LREASMLALP-VLVSLINLLLP 489
Query: 464 EIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIVC----AKHNT 519
+F+ E Y P + L +S G++C +
Sbjct: 490 GLFNLSAWMEDYESP-------------SVRTYVSIGRNLILKVSILGVLCYHWLGRVAA 536
Query: 520 DTT-KLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFY 578
D K++CWE++VGQ+ Y+ ++ +F + T L + R R LK + F
Sbjct: 537 DPQLKVQCWESFVGQELYRFLIMEFIFALLDTLFGEL----LWRLFSERVLKRRRKPVFD 592
Query: 579 LPKHVLDIVYVQTIIWMAM 597
+ ++VL+++Y QT+ W+ +
Sbjct: 593 IARNVLELIYGQTLAWLGV 611
>UniRef50_UPI00015A7BA3 Cluster: Transmembrane channel-like protein
3.; n=1; Danio rerio|Rep: Transmembrane channel-like
protein 3. - Danio rerio
Length = 655
Score = 72.1 bits (169), Expect = 4e-11
Identities = 64/242 (26%), Positives = 107/242 (44%), Gaps = 26/242 (10%)
Query: 168 WQTPMREIEGK--FGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDET 225
W+ +++IE K FG+GV SY ++I+ F++LP+ LL + T
Sbjct: 87 WEMRIKKIENKGHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVLPE-LLAGAPFG---T 142
Query: 226 EANSTVCCSIAYFEKNTTNSNIFLDVIQGTG-WMERTILFYGVYTDQIYTYYVNSLYHTK 284
+ T+ K S LD I G +++ ++LFYG YY N
Sbjct: 143 TRSKTI-------PKEHFASAQDLDTIWSLGGYLQYSVLFYG--------YYGNVRKIGS 187
Query: 285 LFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHN 344
Y +P+AY LV ++ S I +++ A+ + L + + Y +C VF WD+ I N
Sbjct: 188 AGYRLPLAYFLVGMAVFAYSFITLLRKMAKNSRMSLAGASDENYTFCWRVFCAWDYLIGN 247
Query: 345 DRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFL 404
+A K A+ N I+ I EE+ K++ S Q+ + + R S ++
Sbjct: 248 LEAAESKGAAIVNSIREAIVEEQEKKKDTS----LQVFLFILRILANILVLLSLTGSIYI 303
Query: 405 IY 406
IY
Sbjct: 304 IY 305
Score = 52.8 bits (121), Expect = 3e-05
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCL----KMFGEQ-EFYLP 580
CWETYVGQ+ KL + D + LI+ R + R+ C F E EF +
Sbjct: 434 CWETYVGQEMLKLSIIDMIFTVASILLIDFIRGLVVRYLSDCCCWDLESKFPEYGEFKIA 493
Query: 581 KHVLDIVYVQTIIWMAMF 598
++VL ++Y Q +IWM F
Sbjct: 494 ENVLHLIYNQGMIWMGAF 511
>UniRef50_Q4SN83 Cluster: Chromosome 8 SCAF14543, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 8
SCAF14543, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1179
Score = 71.7 bits (168), Expect = 5e-11
Identities = 28/70 (40%), Positives = 43/70 (61%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWET VGQ+ YKL + D + T L+ PR + H+ + ++ G QEF +P +VL
Sbjct: 961 QCWETRVGQEMYKLTVFDLLIAVATLVLVEFPRRMVVDHSSNALVQKLGRQEFVIPSNVL 1020
Query: 585 DIVYVQTIIW 594
+VY QT++W
Sbjct: 1021 VLVYGQTVVW 1030
Score = 56.8 bits (131), Expect = 2e-06
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Query: 249 LDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAI 308
LDV+ GTG++E + LFYG +Y N++ + FYN+P+AY+L + LI I
Sbjct: 651 LDVLLGTGFVELSYLFYG--------FYENTVVEDRNFYNIPLAYLLTAAFYFAFCLICI 702
Query: 309 VKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQ 353
V + + +Y + F GWD+ D+ ++K +
Sbjct: 703 VVRLGYAARVAVATGGQTGGEYSMIAFAGWDYGSLGDKETKLKQK 747
>UniRef50_Q7Z015 Cluster: TmcA-like protein; n=3; Culicidae|Rep:
TmcA-like protein - Anopheles gambiae (African malaria
mosquito)
Length = 814
Score = 69.3 bits (162), Expect = 3e-10
Identities = 73/302 (24%), Positives = 140/302 (46%), Gaps = 35/302 (11%)
Query: 97 ENLSNEERSWEEIMQ-IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQR---KVWH 152
+ L + R +E++Q +K P+ M +K+ L + ++ R +G Q H R +
Sbjct: 49 DKLFDTIRLHKEVLQTVKLQPISMKRKLRLVQQAKSYIT-RHEGALQEHFTSRTARSLLA 107
Query: 153 RFRIGCTETFSKL--EL---------WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTIS 201
+F I T + +L EL W++ ++EIE FG+ V SY IS
Sbjct: 108 QFNIFLTTKWQQLLRELANLATYLIPWESRIKEIESHFGSVVASYFTFLRWLFSVNIVIS 167
Query: 202 ILVIVFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERT 261
+L++VF+++P E +Y D +A + +++ E T + F + + G ++ +
Sbjct: 168 VLLVVFIMVP-----EEIY-VDPEKAKCDIRKTMSKQELALTRN--FSTIWEFEGHLKYS 219
Query: 262 ILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLI 321
LFYG Y+ T+ + YN+P+AY + + S +A +K A + +
Sbjct: 220 PLFYGYYS----TFSGAIAWG----YNLPLAYFFTGLVVYIYSFVATLKKMAENSRMSKL 271
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQI 381
S+ Y + +F GWD+ I + +A+ + ++ K + EE EK+ +R +I
Sbjct: 272 SSKDDEYVFSWKLFTGWDYMIGHMETAQNRMASIILGFKEALLEE---AEKKKDTRNWKI 328
Query: 382 LM 383
++
Sbjct: 329 IL 330
Score = 50.0 bits (114), Expect = 2e-04
Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
Query: 518 NTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCL---KMFG 573
N D L CWET GQ+ KL + D V V+T +++ RA R+ S C K F
Sbjct: 474 NADIRSL-CWETMFGQELAKLTVMDLLVTIVSTLILDFLRALFVRYMNSCWCWDLEKKFP 532
Query: 574 EQ-EFYLPKHVLDIVYVQTIIWMAMF 598
+ +F + +++L +V Q ++WM MF
Sbjct: 533 KYGDFKIAENILHLVNNQGMVWMGMF 558
>UniRef50_Q8TDI7 Cluster: Transmembrane channel-like protein 2;
n=61; Euteleostomi|Rep: Transmembrane channel-like
protein 2 - Homo sapiens (Human)
Length = 906
Score = 68.9 bits (161), Expect = 4e-10
Identities = 79/364 (21%), Positives = 150/364 (41%), Gaps = 33/364 (9%)
Query: 51 TLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIM 110
T P ++ ++++ Q R S+ A + + LS +L++ L E + I
Sbjct: 111 TAAPKREKEIPRKEEKSKRQKKPRSSSLASSASGGE-SLSE-EELAQILEQVEEKKKLIA 168
Query: 111 QIKALPVPMSQKI-ELKARLQNATK----LRLQGFEQLH---LRQRKVWHRFRIGCTETF 162
+++ P PM++K+ EL+ + K L +QL+ + K W +F+
Sbjct: 169 TMRSKPWPMAKKLTELREAQEFVEKYEGALGKGKGKQLYAYKMLMAKKWVKFKRDFDNFK 228
Query: 163 SKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYEC 222
++ W+ +++IE FG+ V SY + L+ +I+P+ L+
Sbjct: 229 TQCIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSI 288
Query: 223 DETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYH 282
E+ + ++ D G+++ + LFYG Y +Q ++
Sbjct: 289 PRKTVPRAE-------EEKAMDFSVLWDF---EGYIKYSALFYGYYNNQRTIGWLR---- 334
Query: 283 TKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCI 342
Y +PMAY +V +S SLI ++++ A + E E + + +F WD+ I
Sbjct: 335 ----YRLPMAYFMVGVSVFGYSLIIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLI 390
Query: 343 HNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASG 402
N +A K+ ++ K E I +E++S E+ L R SG
Sbjct: 391 GNSETADNKYASITTSFK-----ESIVDEQESNKEENIHLTRFLRVLANFLIICCLCGSG 445
Query: 403 FLIY 406
+LIY
Sbjct: 446 YLIY 449
Score = 45.6 bits (103), Expect = 0.004
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKMF--- 572
H D + CWET VG +F +L ++D V ++T L + RA R C +
Sbjct: 565 HPADVPRGSCWETAVGIEFMRLTVSDMLVTYITILLGDFLRACFVRFMNYCWCWDLEAGF 624
Query: 573 -GEQEFYLPKHVLDIVYVQTIIWMAMF 598
EF + +VL +++ Q +IWM F
Sbjct: 625 PSYAEFDISGNVLGLIFNQGMIWMGSF 651
>UniRef50_A7SZG0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 233
Score = 68.5 bits (160), Expect = 5e-10
Identities = 61/241 (25%), Positives = 110/241 (45%), Gaps = 31/241 (12%)
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ +R+I+G FG G+ S+ + + +F+I+P+ L A
Sbjct: 14 WEKRIRKIQGHFGAGIGSFFLFLRSLVWVNTVMFVFTTLFIIVPQIL------------A 61
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFY 287
ST S ++ ++++ + +I G +E + LFYG Y+++ SL + Y
Sbjct: 62 PST---STKMPDELRSSASSLIAIIDAKGHLEYSFLFYGYYSNK-------SLQIGNVRY 111
Query: 288 NMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQF--YKYCNLVFGGWDFCIHND 345
+P+AYI+V + + S++ I++ A+ +Q+ +S GQ YK+ VF WDF I
Sbjct: 112 PLPLAYIVVFLGTYVFSVLTILRAMAQ--EQRNSQSSGQHDQYKFGWRVFTAWDFLITEK 169
Query: 346 RSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLI 405
+A K ++ IK E+I EE + E+ L+ R SG+ I
Sbjct: 170 ETAENKVASITTTIK-----EQILEETEKAKEENIHLLRFLRVLANFLVICVLGGSGYAI 224
Query: 406 Y 406
+
Sbjct: 225 F 225
>UniRef50_UPI0000DB7B12 Cluster: PREDICTED: similar to CG3280-PA,
partial; n=2; Apis mellifera|Rep: PREDICTED: similar to
CG3280-PA, partial - Apis mellifera
Length = 1129
Score = 66.5 bits (155), Expect = 2e-09
Identities = 79/336 (23%), Positives = 146/336 (43%), Gaps = 38/336 (11%)
Query: 55 SKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLS-ENLSNEERSWEEIMQ-I 112
S++ R ++ +++ R+ + A T+ S + +SM S E + + + +E++ +
Sbjct: 29 SRRKRRPSSPFSIEAESMLRRRSSACTISSEETAISMEEGGSQEQIFEKLKLHKEVLSGV 88
Query: 113 KALPVPMSQKIELKA-------RLQNATKLRL-------QGFEQLHLRQRKVWHRFRIGC 158
K P P+ +KI+L R + A + RL ++ L K W FR
Sbjct: 89 KQQPWPLRRKIKLVRQAKSYVRRHEGALQERLAHTRSTKDAIARVSLFATKKWQYFRREI 148
Query: 159 TETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTER 218
+ L W+ ++EIE FG+ V SY ++I+++ F+ +P+ +LT
Sbjct: 149 VNLETWLIPWEFRIKEIESHFGSAVASYFIFLRWLFWINLVMAIILVAFVAIPE-MLTAD 207
Query: 219 VYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVN 278
V E + E+ S L + + G ++ + FYG YT+Q
Sbjct: 208 VTMAGERKV---------MLEEERIKSKHLLTLWEFEGILKYSPFFYGWYTNQ------- 251
Query: 279 SLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFK-QKLIESEGQFYKYCNLVFGG 337
++ Y +P+AY + + + S +AI++ A + KL E E + + +F G
Sbjct: 252 ---DSQSGYRLPLAYFVTNLVVYIYSFLAILRKMAENSRLSKLSEKEDEC-AFSWRLFTG 307
Query: 338 WDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQ 373
WDF I N +A + L K + EE KE+ +
Sbjct: 308 WDFMIGNPETAHNRTANLVLGFKEALLEEAEKEKDE 343
Score = 43.6 bits (98), Expect = 0.016
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCL---KMFGEQ-EFYLP 580
CWET GQ+ KL + D + T I+ RA R C K F + +F +
Sbjct: 763 CWETVFGQELAKLTVMDLIIIIANTLTIDFIRAVFVRFMNGCWCWDLEKQFPQYGDFKIA 822
Query: 581 KHVLDIVYVQTIIWMAMF 598
+++L +V Q +IWM MF
Sbjct: 823 ENILHLVLNQGMIWMGMF 840
>UniRef50_UPI0001556598 Cluster: PREDICTED: similar to Tmc8 protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to Tmc8 protein, partial - Ornithorhynchus
anatinus
Length = 487
Score = 63.3 bits (147), Expect = 2e-08
Identities = 26/73 (35%), Positives = 41/73 (56%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLD 585
CWE + Q+ YKL + +F + TFL++LPR + G +EF + K+VLD
Sbjct: 174 CWENAIAQEMYKLCIFNFLLTVAFTFLVSLPRRLLVERFSGPLWVWLGREEFTVSKNVLD 233
Query: 586 IVYVQTIIWMAMF 598
++ QT+ WM +F
Sbjct: 234 LMAGQTVTWMGLF 246
>UniRef50_Q5YCC8 Cluster: Transmembrane channel-like 2; n=6;
Amniota|Rep: Transmembrane channel-like 2 - Gallus
gallus (Chicken)
Length = 864
Score = 62.1 bits (144), Expect = 4e-08
Identities = 58/258 (22%), Positives = 106/258 (41%), Gaps = 23/258 (8%)
Query: 149 KVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFL 208
K W +F+ ++ W+ ++E+E FG+ V SY + L+ +
Sbjct: 159 KKWVKFKRDFDNFKTQCIPWEMKIKEVESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLV 218
Query: 209 ILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVY 268
I+P+ L+ S ++ E+ T F + G+++ + LFYG Y
Sbjct: 219 IIPEVLMG--------MPYGSMPRKTVPRAEQATAMD--FSVLWDFEGYIKYSALFYGYY 268
Query: 269 TDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFY 328
+Q ++ Y +PMAY +V IS SL+ ++++ AR + + + +
Sbjct: 269 NNQRTIGWLK--------YRLPMAYFMVGISVFGYSLMVVIRSMARNANESTADGDDDNF 320
Query: 329 KYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRX 388
+ +F WD+ I N +A K ++ K E I +E++S E+ L R
Sbjct: 321 VFSWKMFTSWDYLIGNPETADNKFASITTSFK-----ESIVDEQESNKDENIHLRRFLRV 375
Query: 389 XXXXXXXXXXXASGFLIY 406
SG+LIY
Sbjct: 376 LANVLIICCLCGSGYLIY 393
Score = 41.1 bits (92), Expect = 0.084
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 520 DTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKMF----GE 574
D + CWET VG + +L ++D V FVT + + RA R C +
Sbjct: 512 DVPRGPCWETTVGIEIVRLTVSDILVTFVTILVGDFIRACFVRFMNYCWCWDLEAGFPSY 571
Query: 575 QEFYLPKHVLDIVYVQTIIWMAMF 598
EF + +VL +V+ Q +IWM F
Sbjct: 572 AEFDISGNVLGLVFNQGMIWMGSF 595
>UniRef50_Q9VT17 Cluster: CG3280-PA; n=1; Drosophila
melanogaster|Rep: CG3280-PA - Drosophila melanogaster
(Fruit fly)
Length = 1937
Score = 61.7 bits (143), Expect = 6e-08
Identities = 77/343 (22%), Positives = 146/343 (42%), Gaps = 40/343 (11%)
Query: 59 RNTTTVKRARSQTDRRQSTFARTMQSRDI--HLSMLPDLSENLSNEERSWEEIMQ-IKAL 115
R ++ + +RR+S+ T + + + E + R +E++Q +K
Sbjct: 105 RASSPMDHVLDSVERRRSSVYTTSSGKSVVQEGTNQESTQEQIFENIRLHKEVIQSVKLQ 164
Query: 116 PVPMSQKIELKARLQNATKLRLQGFEQ----LHLRQRKVWHRFRIGCT--------ETFS 163
P P+ +K++L R R +G Q + R +W RF+I ET S
Sbjct: 165 PWPIRKKLKL-VRQAKTYVARHEGALQERFAMSRSTRDLWARFKILMAARWRHWKRETAS 223
Query: 164 KLEL---WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVY 220
L + W+ ++EIE FG+GV SY I+I ++ F+I P+ T+
Sbjct: 224 FLTVLIPWELRIKEIESHFGSGVASYFTFLRWLMWVNIMIAIPLVAFVIGPEYFATKH-G 282
Query: 221 ECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSL 280
E D + S +A N+F + G+++ + +FYG YY ++
Sbjct: 283 ETDPRKRMSDPEARVA--------GNLF-TFWEFEGYLKYSPMFYG--------YYSSTS 325
Query: 281 YHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDF 340
+ Y +P+AY L + + S +A ++ A + + S+ + +F GWDF
Sbjct: 326 GISTSGYKLPLAYFLTAVLVYIYSFVATLRKMAENSRNSKLSSKDDECVFSWKLFTGWDF 385
Query: 341 CIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILM 383
I + +A H + + + G E + EK+ +R ++++
Sbjct: 386 MIGHAETA---HNRIASVVVGFKEALLEEAEKKKDNRNWRVIL 425
Score = 41.1 bits (92), Expect = 0.084
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSR-CL---KMFGEQ-EFYLP 580
CWET +GQ+ K+I+ D + V I+ RA R+ C K F + +F +
Sbjct: 1138 CWETSLGQELSKVIVFDGLMSIVAPLCIDFLRALFVRYVNQNWCWDMEKTFPQYGDFKIA 1197
Query: 581 KHVLDIVYVQTIIWMAMF 598
+++L ++ Q +WM +F
Sbjct: 1198 ENILTLINNQGQVWMGIF 1215
>UniRef50_Q11069 Cluster: TMC family membrane protein B0416.1; n=2;
Caenorhabditis|Rep: TMC family membrane protein B0416.1
- Caenorhabditis elegans
Length = 1203
Score = 60.5 bits (140), Expect = 1e-07
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 10/203 (4%)
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ +R+IE FG+ V SY TI+ ++ +F+++P+ L R D+
Sbjct: 166 WEAKIRKIESHFGSVVSSYFTFHRWVLGVNITITFIMCMFVVIPEWLADSRTQFGDD-RY 224
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFY 287
N T + ++ V G+ + ++LFYG Y+ + + + + Y
Sbjct: 225 NKTKAIKVMP-PAVRARADELSTVWDFGGYFQYSLLFYGFYSKETF-------FGETIKY 276
Query: 288 NMPMAYILVPISWTLLSLIAIV-KTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDR 346
+P+AY I SL I+ K AA + L + Q Y + F GWD+ I N
Sbjct: 277 RVPVAYFFCNIFILGFSLFIILRKMAANNRRGTLSSGKTQQYLFNWKAFTGWDYTIGNPE 336
Query: 347 SARIKHQALYNEIKGCIEEERIK 369
+A + A + + I +++ K
Sbjct: 337 TAGNVYMANVIKFREAINDDKQK 359
Score = 44.4 bits (100), Expect = 0.009
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 9/80 (11%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-------SRCLKMFGEQEFY 578
CWET +GQ+ KL+ D + + FLI+ R R+ R +G EF
Sbjct: 594 CWETIIGQEITKLVTMDLYMTVASIFLIDFLRGLACRYLNLYWPWDLERTFPEYG--EFK 651
Query: 579 LPKHVLDIVYVQTIIWMAMF 598
+ ++VL +V Q +IW+ +F
Sbjct: 652 VAENVLHLVNNQGMIWLGLF 671
>UniRef50_Q6DH78 Cluster: Zgc:92610; n=2; Danio rerio|Rep: Zgc:92610
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 554
Score = 59.3 bits (137), Expect = 3e-07
Identities = 47/182 (25%), Positives = 86/182 (47%), Gaps = 21/182 (11%)
Query: 95 LSENLSNEERSWEEIMQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVW--H 152
L NL N S + + ++A+P+ +++K EL+ + N + L + Q K + +
Sbjct: 112 LVNNLQNLSVS-DRVRMLRAMPLSLAEKKELRMLVLNKGEHSLSENQIPCCSQLKYYIIN 170
Query: 153 RFRIGC---TETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLI 209
R G S L+LWQT ++ + G+FGTGV+SY + + +FL
Sbjct: 171 AVRHGWYSWLSLVSSLQLWQTALKCVSGRFGTGVLSYFVFLRTLLFFNIFLFLFTALFLA 230
Query: 210 LPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYT 269
+P+ +L +T N+T + S+ L+V+ G G+ ++L+YG Y+
Sbjct: 231 VPQAVLP----PAQDTHTNNT-----------SRRSSWGLEVLTGAGYFSDSVLYYGYYS 275
Query: 270 DQ 271
+Q
Sbjct: 276 NQ 277
>UniRef50_Q29CY9 Cluster: GA17148-PA; n=1; Drosophila
pseudoobscura|Rep: GA17148-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 1935
Score = 58.4 bits (135), Expect = 5e-07
Identities = 72/299 (24%), Positives = 124/299 (41%), Gaps = 38/299 (12%)
Query: 59 RNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVP 118
R ++ + +RR+S+ T + + S + EN+ + E I +K P P
Sbjct: 159 RASSPMDHVLDSVERRRSSVYTTKEGTNQE-STQEQIFENIRLHK---EVIQSVKLQPWP 214
Query: 119 MSQKIELKARLQNATKLRLQGFEQ----LHLRQRKVWHRFRIGCT--------ETFSKLE 166
+ +K++L R R +G Q + R +W RF+I ET S L
Sbjct: 215 IRKKLKL-VRQAKTYVARHEGALQERFAMSRSTRDLWARFKILMAARWRHWKRETTSFLT 273
Query: 167 L---WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECD 223
+ W+ ++EIE FG+GV SY I+I ++ F+I P+ T+
Sbjct: 274 VLIPWELRIKEIESHFGSGVASYFTFLRWLMWVNIMIAIPLVAFVIGPEYFATKH----G 329
Query: 224 ETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHT 283
ET+ + + E+N N+F T W L Y+ Y YY ++ +
Sbjct: 330 ETDPRKRMTDA----ERNVA-GNLF------TFWEFEGFL---KYSPMFYGYYSSTSGIS 375
Query: 284 KLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCI 342
Y +P+AY L + + S +A ++ A + + S+ + +F GWDF I
Sbjct: 376 VSGYKLPLAYFLTAVLVYIYSFVATLRKMAENSRNSKLSSKDDECVFSWKLFTGWDFMI 434
Score = 41.1 bits (92), Expect = 0.084
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSR-CL---KMFGEQ-EFYLP 580
CWET +GQ+ K+I+ D + V I+ RA R+ C K F + +F +
Sbjct: 1129 CWETSLGQELSKVIVFDGLMSIVAPLCIDFLRALFVRYVNQNWCWDMEKTFPQYGDFKIA 1188
Query: 581 KHVLDIVYVQTIIWMAMF 598
+++L ++ Q +WM +F
Sbjct: 1189 ENILTLINNQGQVWMGIF 1206
>UniRef50_UPI00015A78D8 Cluster: UPI00015A78D8 related cluster; n=2;
Danio rerio|Rep: UPI00015A78D8 UniRef100 entry - Danio
rerio
Length = 600
Score = 58.0 bits (134), Expect = 7e-07
Identities = 50/210 (23%), Positives = 92/210 (43%), Gaps = 24/210 (11%)
Query: 165 LELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDE 224
L+LWQ + I FG GV+SY + ++ +FL+LP+
Sbjct: 85 LQLWQKVFKNISAHFGMGVLSYFVFLRRLLLFNLLLMLINGLFLLLPQL----------S 134
Query: 225 TEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTK 284
++ST S A + N L ++ G G + +++FYG Y+D N
Sbjct: 135 NPSSSTRTSSEAEHKSN-------LWMLTGMGILTDSVMFYGHYSD-----CQNGSSECF 182
Query: 285 LFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHN 344
YN+P+AYI + ++ + +V ++ F + +S VF WDF ++
Sbjct: 183 ENYNIPLAYIFTFGTGMFVTCVKLVYNMSKAFGKS--QSSTNTRSLVFKVFCSWDFKVYK 240
Query: 345 DRSARIKHQALYNEIKGCIEEERIKEEKQS 374
RS R++ + ++K + E K++K++
Sbjct: 241 KRSVRLQSVNICTQLKEMLSELSCKKQKRN 270
Score = 48.4 bits (110), Expect = 6e-04
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 8/76 (10%)
Query: 522 TKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPK 581
+ L+CWET VGQ+ Y+LI+ D F ++I L + F T R + EF + +
Sbjct: 386 SSLQCWETMVGQELYRLIVMDLI--FEVLYII-LAQFFWGNVTLRR-----RKLEFAIAQ 437
Query: 582 HVLDIVYVQTIIWMAM 597
VL+++Y QT++W +
Sbjct: 438 EVLELIYSQTLVWFGV 453
>UniRef50_UPI0000E81009 Cluster: PREDICTED: similar to Transmembrane
channel-like gene family 5; n=2; Gallus gallus|Rep:
PREDICTED: similar to Transmembrane channel-like gene
family 5 - Gallus gallus
Length = 648
Score = 56.4 bits (130), Expect = 2e-06
Identities = 42/160 (26%), Positives = 70/160 (43%), Gaps = 19/160 (11%)
Query: 440 NQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXX 499
N LE+ + I +LN+++P +S++ E + P
Sbjct: 236 NDLESQAAMLVLAIVTSLLNVVLPFFYSWLGNLEKFQDPKNKIYVTIARI---------- 285
Query: 500 XXQIYLYISTNGIVCAK--HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPR 557
I L IS GI+C + ++ +CWET VGQ Y+L+L DF + +F
Sbjct: 286 ---IILKISIIGILCYYWLNVVAASESQCWETLVGQDIYRLVLVDFIFCLLGSFF----G 338
Query: 558 AFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAM 597
F+ R + G EF + + VLD++Y QT+ W+ +
Sbjct: 339 EFLRRIIGTTVYIRLGVPEFDIGRSVLDLIYAQTLTWIGI 378
>UniRef50_Q7T1T9 Cluster: Tmc6-related protein 2; n=3;
Tetraodontidae|Rep: Tmc6-related protein 2 - Fugu
rubripes (Japanese pufferfish) (Takifugu rubripes)
Length = 690
Score = 55.6 bits (128), Expect = 4e-06
Identities = 47/212 (22%), Positives = 94/212 (44%), Gaps = 27/212 (12%)
Query: 163 SKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYEC 222
S L+LW + ++ + G+FGTGV+SY + + +FLI P+ + + +
Sbjct: 155 SSLQLWHSALKNLSGRFGTGVLSYFLFLRTLLLSNLLLFAITGLFLIFPQAINPPHLPD- 213
Query: 223 DETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIY-TYYVNSLY 281
N N +S D++ GTG + ++++FYG Y I T SL
Sbjct: 214 -----NPM---------DNPPDSLNNFDLLMGTGSLSQSLMFYGYYNGSIIRTCAATSLS 259
Query: 282 HTK----LFYNMPMAYILVP-ISWTLLSLIAIVK---TAARGFKQKLIESEGQFYKYCNL 333
T + Y++P AY L I++ + +I + + + G ++E+
Sbjct: 260 STDCAQVMLYSIPAAYFLTTIITFFAICIILVYRWDMSTTFGRSFHILEAPRMM---AVK 316
Query: 334 VFGGWDFCIHNDRSARIKHQALYNEIKGCIEE 365
VF WDF ++ S +++ + + +++ + +
Sbjct: 317 VFSSWDFKVNKKSSVKLQSKKISTQLRELLSD 348
Score = 49.6 bits (113), Expect = 2e-04
Identities = 24/74 (32%), Positives = 41/74 (55%), Gaps = 8/74 (10%)
Query: 524 LECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHV 583
L+CWE++VGQ+ Y+L+L DF + TFL + LK + F + ++V
Sbjct: 473 LQCWESFVGQELYRLLLVDFVFTALHTFL--------GEFLWGQLLKRRRKPGFDIARNV 524
Query: 584 LDIVYVQTIIWMAM 597
L+++Y QT+ W +
Sbjct: 525 LELIYGQTLTWFGV 538
>UniRef50_UPI0000D57404 Cluster: PREDICTED: similar to T13G4.3; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to T13G4.3 -
Tribolium castaneum
Length = 1286
Score = 54.4 bits (125), Expect = 8e-06
Identities = 53/224 (23%), Positives = 88/224 (39%), Gaps = 19/224 (8%)
Query: 149 KVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFL 208
K W +R + L W+ ++EIE FG+ V SY + I++I F+
Sbjct: 232 KKWQHYRRELANLSNWLVPWERKIKEIESHFGSVVASYFLFLRWLFWVNVVLGIVLISFV 291
Query: 209 ILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVY 268
+P+ L +C +A + Y N+TN D G + + LFYG Y
Sbjct: 292 AVPEHFLA----KCAVPDARKQILKEERY---NSTNFQTLWDF---GGVFKYSPLFYGWY 341
Query: 269 TDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFY 328
T Y S K Y MP AY + + S A ++ A + + +
Sbjct: 342 T------YKES---KKSGYRMPFAYFITGLVAYAYSFFATLRKMAENSRMSKLSEKDDEC 392
Query: 329 KYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEK 372
+ +F WD+ I N +A + ++ K + EE K+ +
Sbjct: 393 IFSWKLFTAWDYMIGNAETAHNRIASIVVGFKEALLEEAEKKRE 436
Score = 43.6 bits (98), Expect = 0.016
Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 7/79 (8%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCL-----KMFGEQ-EFYL 579
CWET GQ+ KL + D + ++T ++ R R +RC K+F + +F +
Sbjct: 744 CWETNFGQELIKLTVMDLVMTILSTLAMDFIRGIFVRF-MNRCWCWDLEKVFPQYGDFKV 802
Query: 580 PKHVLDIVYVQTIIWMAMF 598
+++L +V Q ++WM MF
Sbjct: 803 AENILHLVNNQGMVWMGMF 821
>UniRef50_UPI0000F1DB4A Cluster: PREDICTED: similar to Tmc6-related
protein 1; n=1; Danio rerio|Rep: PREDICTED: similar to
Tmc6-related protein 1 - Danio rerio
Length = 414
Score = 52.0 bits (119), Expect = 5e-05
Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWET VGQ+ Y+LI+ D + + L F R+ R K+ EF + + VL
Sbjct: 177 KCWETMVGQELYRLIVMDLIFEVLYIILAQFFWGFCVRNVTLRRRKL----EFAIAQEVL 232
Query: 585 DIVYVQTIIWMAM 597
+++Y QT++W +
Sbjct: 233 ELIYSQTLVWFGV 245
>UniRef50_Q7Z014 Cluster: TmcB-like protein; n=3; Culicidae|Rep:
TmcB-like protein - Anopheles gambiae (African malaria
mosquito)
Length = 705
Score = 50.4 bits (115), Expect = 1e-04
Identities = 25/112 (22%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Query: 250 DVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIV 309
D++ G G++ ++++YG Y+++ +T + Y++P AY L L + + +
Sbjct: 167 DLLTGEGYLSDSVMYYGSYSNRSFTLVPGTAE-----YSLPHAYFLTITILLLATFVFVS 221
Query: 310 KTAARGFKQKLIESEGQFYKYC-NLVFGGWDFCIHNDRSARIKHQALYNEIK 360
+ ++ IES + + WD+ I N ++AR+KH + +E++
Sbjct: 222 VSMGHAYRISFIESSATVQNILTHKIVCSWDYGIANGKAARLKHATILSELR 273
Score = 42.3 bits (95), Expect = 0.036
Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 12/81 (14%)
Query: 526 CWETYVGQQFYKLILTDFAVQFVTTFLINLPRA----FMARHTRSR-----CLKMFGEQE 576
CWET +GQ+ Y+L++ DF F++T L++ R AR+ +R
Sbjct: 399 CWETAIGQELYRLLVVDF---FISTVLLSAVRGVRYLLHARYGPARGRAGPLAPYLTPPP 455
Query: 577 FYLPKHVLDIVYVQTIIWMAM 597
F + H L +VY QT++W +
Sbjct: 456 FCIETHSLGLVYNQTLLWFGV 476
>UniRef50_Q7T1T8 Cluster: Tmc5 protein; n=3; Clupeocephala|Rep: Tmc5
protein - Fugu rubripes (Japanese pufferfish) (Takifugu
rubripes)
Length = 583
Score = 50.0 bits (114), Expect = 2e-04
Identities = 50/221 (22%), Positives = 93/221 (42%), Gaps = 28/221 (12%)
Query: 165 LELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDE 224
L+LW M+EI G+FGT V++Y ++ F+ +P LL VY+
Sbjct: 74 LQLWHGTMKEIGGRFGTSVLTYFLFLKWLLMFNVVSFLINFGFITIP--LL---VYDHSP 128
Query: 225 TEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTK 284
S L+++ G G+ ++L+YG Y+++ V
Sbjct: 129 NIPEGV--------------SFRGLELLTGAGYFNYSVLYYGSYSNETLVGLVA------ 168
Query: 285 LFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHN 344
Y+M +AY + +L IA++ + A+ FK+ + ++ L+ WDF + N
Sbjct: 169 --YDMKLAYFFTISLYMVLCGIALIFSMAKSFKKNYVLADPASNSAWQLLC-TWDFSVTN 225
Query: 345 DRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
+R+ + + L ++K + E KE + +HL
Sbjct: 226 ERAVKQRKNNLSVQLKESLSEGAQKEMLTLSEKMKHFGVHL 266
Score = 46.4 bits (105), Expect = 0.002
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 8/76 (10%)
Query: 523 KLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKH 582
K CWE+ VGQ Y+L+ D FL L +F L G EF + ++
Sbjct: 366 KFSCWESMVGQALYRLVFFD--------FLFLLLGSFFGEFLSKWLLPSLGVPEFDVARN 417
Query: 583 VLDIVYVQTIIWMAMF 598
V +++Y QT+ W+ ++
Sbjct: 418 VFELIYAQTLSWIGIY 433
>UniRef50_Q61X36 Cluster: Putative uncharacterized protein CBG04140;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein CBG04140 - Caenorhabditis briggsae
Length = 1098
Score = 50.0 bits (114), Expect = 2e-04
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 10/131 (7%)
Query: 256 GWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIV-KTAAR 314
G++ + LFYG Y+D + K+ Y +P+AY +V ++ S AI+ K AA
Sbjct: 46 GYLRYSPLFYGYYSDDPFL-------GNKIKYALPLAYFMVTLTIFAYSFFAILRKMAAN 98
Query: 315 GFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQS 374
KL S+ + Y + +F GWD+ I N +A A+ +++ I + IK++
Sbjct: 99 ARMSKLSGSKAEQYIFNWKLFTGWDYTIGNSETASNTVMAVVIKLRESIAD--IKKDSHG 156
Query: 375 RSRESQILMHL 385
+ R Q + +
Sbjct: 157 KFRLLQFTLRV 167
Score = 42.7 bits (96), Expect = 0.028
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 9/87 (10%)
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCLKM---F 572
HN D CWET +GQ+ KL+ D ++ +I+ R ++ S C + F
Sbjct: 476 HNNDI----CWETIIGQEIVKLVTMDLIFTILSILVIDFLRGLWIKYCSSWWCWDIETTF 531
Query: 573 GEQ-EFYLPKHVLDIVYVQTIIWMAMF 598
E EF + ++VL I+ Q +IW+ +F
Sbjct: 532 PEYGEFKVAENVLHIINNQGMIWLGLF 558
>UniRef50_Q7Z403 Cluster: Transmembrane channel-like protein 6;
n=27; Tetrapoda|Rep: Transmembrane channel-like protein
6 - Homo sapiens (Human)
Length = 805
Score = 50.0 bits (114), Expect = 2e-04
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ DF + + T L + R + LK + EF + ++VL
Sbjct: 539 QCWEDFVGQELYRFLVMDFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 594
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 595 ELIYGQTLTWLGV 607
Score = 46.8 bits (106), Expect = 0.002
Identities = 49/244 (20%), Positives = 100/244 (40%), Gaps = 36/244 (14%)
Query: 152 HRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILP 211
H + L W+ ++ I G+FG+ V+SY + +L++ F++ P
Sbjct: 214 HSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGP 273
Query: 212 KTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQ 271
+ + + VC L+++ G G T+++YG Y++
Sbjct: 274 QVAFPPAL------PGPAPVCTG--------------LELLTGAGCFTHTVMYYGHYSNA 313
Query: 272 IYTYYVNSLYHTK--------LFYNMPMAYI-LVPISWTLLSLIAIVKTAARGFKQKL-I 321
S L YNMP+AY+ V +S+ ++ I +V + A F + +
Sbjct: 314 TLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSF-FITCITLVYSMAHSFGESYRV 372
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQS---RSRE 378
S + VF WD+ + R++R++ + +K + E +++ +S R R+
Sbjct: 373 GSTSGIHAI--TVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQ 430
Query: 379 SQIL 382
+ +L
Sbjct: 431 AAVL 434
>UniRef50_UPI0001555930 Cluster: PREDICTED: similar to transmembrane
channel-like 6; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to transmembrane channel-like 6 -
Ornithorhynchus anatinus
Length = 369
Score = 48.8 bits (111), Expect = 4e-04
Identities = 23/74 (31%), Positives = 42/74 (56%), Gaps = 7/74 (9%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLP-RAFMARHTRSRCLKMFGEQEFYLPKHV 583
+CWET+VGQ+ Y+ ++TDF + T L R + + R + EF + ++V
Sbjct: 229 QCWETFVGQELYRFMVTDFIFTLLDTLFGELVWRLIIEKREGKR------KPEFDIGRNV 282
Query: 584 LDIVYVQTIIWMAM 597
L+++Y QT+ W+ +
Sbjct: 283 LELIYGQTLTWLGV 296
>UniRef50_Q4S7Q8 Cluster: Chromosome 18 SCAF14712, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF14712, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 832
Score = 48.8 bits (111), Expect = 4e-04
Identities = 51/237 (21%), Positives = 97/237 (40%), Gaps = 29/237 (12%)
Query: 125 LKARLQNATKLRLQGFEQLHLR-QRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGV 183
+K + +T+ R+ L + + K R+ L+LWQ M+EI G+FGT V
Sbjct: 43 VKELVDMSTRERIHAIRDLPMSFEEKKSIRWGYSVRSARQTLQLWQGTMKEIGGRFGTSV 102
Query: 184 VSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTT 243
++Y ++ F+ +P LL D T N
Sbjct: 103 LTYFMFLKWLLVFNVVSFLINFGFITIP--LLVH-----DHTPN----------LPPNVN 145
Query: 244 NSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLL 303
L+++ G G+ T+++YG Y+++ YN+ +AY + +L
Sbjct: 146 FRG--LEILTGAGYFNYTVMYYGSYSNETLVGLGE--------YNLQLAYFFTISLYMVL 195
Query: 304 SLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIK 360
+A++ + A+ FK+ + S+ ++ WDF I N+R+ + L ++K
Sbjct: 196 CGVALIFSMAKSFKENYVLSDPASSSAWQILC-SWDFSIVNERAITQRKNNLSVQLK 251
Score = 41.9 bits (94), Expect = 0.048
Identities = 34/179 (18%), Positives = 73/179 (40%), Gaps = 13/179 (7%)
Query: 400 ASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTT--MSFNQLENVLMEFLPFICIVV 457
+S + I +++FS +NE + ++ + TT S+ L+ +PF+ + +
Sbjct: 220 SSAWQILCSWDFSI--VNERAITQRKNNLSVQLKKTTDDSSWTPLQEAETLLVPFV-VSL 276
Query: 458 LNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYISTNGIVCAKH 517
+NL++P +S ++E Y ++ + + C+
Sbjct: 277 MNLVVPLFYSLFNKFEVYSNQRKQIYVLLVRNVILKISILSILCYYWMQVVAKNLACSP- 335
Query: 518 NTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQE 576
+CWE+ VGQ Y+L+L DF + +F R ++ ++C + + E
Sbjct: 336 -------QCWESMVGQALYRLVLFDFLFLMLGSFFGEFLRKWVYFFKVTKCTLLILQSE 387
>UniRef50_Q5YCC6 Cluster: Transmembrane channel-like 6; n=2;
Amniota|Rep: Transmembrane channel-like 6 - Gallus
gallus (Chicken)
Length = 429
Score = 48.4 bits (110), Expect = 6e-04
Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
ECWET VGQ Y+ ++ DF + T L + R + LK + EF + ++VL
Sbjct: 186 ECWETCVGQDLYRFVVMDFIFTLLDTGFGEL----LWRLILEKKLKSKQKPEFDIARNVL 241
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 242 ELIYGQTLTWLGV 254
Score = 34.7 bits (76), Expect = 7.3
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Query: 283 TKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCI 342
T+L YNMP+AY+ + + I ++ + F + VF WDF +
Sbjct: 36 TQLPYNMPLAYVFTIGASFFATCILLMYSIYHSFGKSYRVGSSTGVLAIK-VFCAWDFKV 94
Query: 343 HNDRSARIKHQALYNEIKGCIEEERIK 369
RS +++ + + ++K + E+R++
Sbjct: 95 VQRRSVKLQSENICTQLKELLAEQRLR 121
>UniRef50_Q4TGL8 Cluster: Chromosome undetermined SCAF3617, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF3617,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 408
Score = 47.2 bits (107), Expect = 0.001
Identities = 45/201 (22%), Positives = 84/201 (41%), Gaps = 28/201 (13%)
Query: 165 LELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDE 224
L+LWQ M+EI G+FGT V++Y ++ F+ +P LL D
Sbjct: 194 LQLWQGTMKEIGGRFGTSVLTYFMFLKWLLVFNVVSFLINFGFITIP--LLVH-----DH 246
Query: 225 TEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTK 284
T N L+++ G G+ T+++YG Y+++
Sbjct: 247 TPN----------LPPNVNFRG--LEILTGAGYFNYTVMYYGSYSNETLVGLGE------ 288
Query: 285 LFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHN 344
YN+ +AY + +L +A++ + A+ FK+ + S+ ++ WD I N
Sbjct: 289 --YNLQLAYFFTISVYMVLCGVALIFSMAKSFKENYVLSDPASSSAWQILC-SWDLSIVN 345
Query: 345 DRSARIKHQALYNEIKGCIEE 365
+R+ + L ++K + E
Sbjct: 346 ERAITQRKNNLSVQLKESLSE 366
>UniRef50_UPI00015A3D40 Cluster: Transmembrane channel-like protein
6 (Epidermodysplasia verruciformis protein 1) (Protein
LAK-4).; n=2; Danio rerio|Rep: Transmembrane
channel-like protein 6 (Epidermodysplasia verruciformis
protein 1) (Protein LAK-4). - Danio rerio
Length = 433
Score = 39.1 bits (87), Expect = 0.34
Identities = 13/28 (46%), Positives = 20/28 (71%)
Query: 524 LECWETYVGQQFYKLILTDFAVQFVTTF 551
L+CWE++VGQ+ Y+ +L DF + TF
Sbjct: 191 LQCWESFVGQELYRFLLMDFIFMLLDTF 218
>UniRef50_Q7K4K7 Cluster: LD35238p; n=2; Sophophora|Rep: LD35238p -
Drosophila melanogaster (Fruit fly)
Length = 611
Score = 36.7 bits (81), Expect = 1.8
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 3/117 (2%)
Query: 34 EQELFDNLQRADAAKLATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLP 93
EQE NLQ+ + KL LL ++ + + R QT + +S + R I S+
Sbjct: 117 EQEKIQNLQQIEIDKLKNLLSFREQESVDRMGLMRQQTQQIESLSEELERLRPIE-SVAE 175
Query: 94 DLSENLSNEERS--WEEIMQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQR 148
DL + L S E+ + L + LK R++ + RL+ +L+ Q+
Sbjct: 176 DLRDELEQLRHSTQQEKNLLTTTLAAVQEENRHLKKRMKIVEESRLESLGKLNSEQQ 232
>UniRef50_Q8IPP9 Cluster: CG31551-PA; n=2; Eukaryota|Rep: CG31551-PA
- Drosophila melanogaster (Fruit fly)
Length = 1393
Score = 36.3 bits (80), Expect = 2.4
Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 41 LQRADAAKLATLLPSKQARNTTTVKRARSQTDRR---QSTFARTMQSRDIHLSMLPDLSE 97
L+ D + TLL + + ++KRAR DRR Q + + + H+ +L E
Sbjct: 240 LREQDRERQRTLLAEQHRLDRQSLKRARQLRDRRLREQQLKVKEQRDHERHM-LLKRREE 298
Query: 98 NLSNEERSWEEIMQIKALPVPMSQKIELKAR 128
E+RSW + + +P SQ +E++ R
Sbjct: 299 RRHQEQRSWPQ----RRPTIPSSQNVEIQQR 325
>UniRef50_UPI0000ECA48E Cluster: Transmembrane channel-like protein
6 (Epidermodysplasia verruciformis protein 1) (Protein
LAK-4).; n=2; Gallus gallus|Rep: Transmembrane
channel-like protein 6 (Epidermodysplasia verruciformis
protein 1) (Protein LAK-4). - Gallus gallus
Length = 467
Score = 35.9 bits (79), Expect = 3.2
Identities = 26/126 (20%), Positives = 56/126 (44%), Gaps = 9/126 (7%)
Query: 252 IQGTGWMERTILFYGVYTDQIY--------TYYVNSLYHTKLFYNMPMAYILVPISWTLL 303
++G G ++L+YG Y++ + + T+L YNMP+AY+ +
Sbjct: 1 LRGAGSFTHSLLYYGYYSNTTLNDPSASSPSGNTSPPRATQLPYNMPLAYVFTIGASFFA 60
Query: 304 SLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCI 363
+ I ++ + F + VF WDF + RS +++ + + ++K +
Sbjct: 61 TCILLMYSIYHSFGKSYRVGSSTGVLAIK-VFCAWDFKVVQRRSVKLQSENICTQLKELL 119
Query: 364 EEERIK 369
E+R++
Sbjct: 120 AEQRLR 125
>UniRef50_A6GE67 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 1071
Score = 35.9 bits (79), Expect = 3.2
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 19 EEAGGEFYQELYPGGEQELFDNLQRADAAKLATLLPSKQARNTTTVKRARSQTDRRQSTF 78
E+ G EF ++ PG + + N QRA A +L+TL +AR + AR+ T+ R F
Sbjct: 338 EDLGIEFPADVRPGDLHQAWAN-QRASAVRLSTLAARLEAR--ASASEARASTEERGQRF 394
Query: 79 ARTMQSRDIHLSMLPDLSENLSNEERSWEEIMQI 112
T + + + D L+ + E + ++
Sbjct: 395 GWTAEELETRRARERDAHRLLAGAIHTLESLAEL 428
>UniRef50_Q4P7S2 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1442
Score = 35.9 bits (79), Expect = 3.2
Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 10/102 (9%)
Query: 44 ADAAKLATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHL-----SMLP--DLS 96
A AA + PS +A +T+T A QT ++ ST +R +R + S LP D +
Sbjct: 619 ASAANDSEESPSDRASSTSTTPSASPQTHKKTSTRSRRPGTRGVSDQTSSDSKLPPRDST 678
Query: 97 ENLSNEERSWEEIMQIKALPVPMSQKIELKARLQNATKLRLQ 138
E + ERSW+ M + L V ++ I A L T L LQ
Sbjct: 679 ERADSTERSWKARMTVVLLQVILALVI---AVLSGVTYLGLQ 717
>UniRef50_UPI0000E0F4DE Cluster: dephospho-CoA kinase; n=1; alpha
proteobacterium HTCC2255|Rep: dephospho-CoA kinase -
alpha proteobacterium HTCC2255
Length = 202
Score = 35.5 bits (78), Expect = 4.2
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 250 DVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSL 305
D++Q G + R L V+ D YT ++N+L H K+ M P S+T+LS+
Sbjct: 59 DILQSDGHLNRAKLRRIVFADPKYTEWLNALLHPKIRAKMLADIADSPSSYTILSI 114
>UniRef50_Q00WH9 Cluster: Chromosome 14 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 14 contig 1, DNA
sequence - Ostreococcus tauri
Length = 386
Score = 35.5 bits (78), Expect = 4.2
Identities = 28/114 (24%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 40 NLQRADAAKLATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLS-MLPDLSEN 98
N DA+KL + + ++ A+ D +S R Q +++ + M D S
Sbjct: 206 NASNIDASKLRQQVVELREERDAALREAQDSRDAAESVMQRRKQHKEVTIKKMAADHSAQ 265
Query: 99 LSN-EERSWEEIMQIKALPVPMSQKIELKARLQNATKLRLQGFE-QLHLRQRKV 150
L E + +EI + KAL V + RL+N + R E ++ +RK+
Sbjct: 266 LKKVREETAKEIKEAKALEVGARWRENACRRLKNQAEARASELEKKIEELERKI 319
>UniRef50_Q5W6K5 Cluster: ABI3-interacting protein-related; n=3;
Oryza sativa|Rep: ABI3-interacting protein-related -
Oryza sativa subsp. japonica (Rice)
Length = 670
Score = 35.1 bits (77), Expect = 5.5
Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 97 ENLSNEERSWEEIMQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRI 156
+N S E+ + +++ L +++ + + R QNA ++ FE +QRK++H
Sbjct: 574 QNQSKEQEQERRMQKLRELRKKKNKRTQRRKRKQNAQVMKQHQFE----KQRKLYHAGSF 629
Query: 157 GCTETFSKLELWQTPMREIEGKFGTGVVSY 186
++++ + E+ + G GT V Y
Sbjct: 630 TNSQSYVRSEIHHHLSQHFSGTIGTPVAPY 659
>UniRef50_Q2V360 Cluster: Uncharacterized protein At5g20450.1; n=2;
Arabidopsis thaliana|Rep: Uncharacterized protein
At5g20450.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 341
Score = 35.1 bits (77), Expect = 5.5
Identities = 26/101 (25%), Positives = 54/101 (53%), Gaps = 5/101 (4%)
Query: 34 EQELFDNLQRADAAKLATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLP 93
+ E F++L A A+L +QA ++ A S+ + R S A +++ + L
Sbjct: 43 DTEKFNSLTSEVEALKASLQSERQAAED--LRNAFSEAEARNSELATNLENVTRRVDQLC 100
Query: 94 DLSENLSNEERSWEEIMQIKALPVPMSQKIELKARLQNATK 134
+ S +L +E+++ E++ KAL + ++ +EL +L+N T+
Sbjct: 101 E-SASLQSEQQAAEDLR--KALSLAEARNLELTTKLENVTR 138
>UniRef50_UPI0000ECA4D7 Cluster: Transmembrane channel-like protein
6 (Epidermodysplasia verruciformis protein 1) (Protein
LAK-4).; n=2; Gallus gallus|Rep: Transmembrane
channel-like protein 6 (Epidermodysplasia verruciformis
protein 1) (Protein LAK-4). - Gallus gallus
Length = 379
Score = 34.7 bits (76), Expect = 7.3
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Query: 283 TKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCI 342
T+L YNMP+AY+ + + I ++ + F + VF WDF +
Sbjct: 35 TQLPYNMPLAYVFTIGASFFATCILLMYSIYHSFGKSYRVGSSTGVLAIK-VFCAWDFKV 93
Query: 343 HNDRSARIKHQALYNEIKGCIEEERIK 369
RS +++ + + ++K + E+R++
Sbjct: 94 VQRRSVKLQSENICTQLKELLAEQRLR 120
>UniRef50_Q4AAN6 Cluster: Putative uncharacterized protein; n=5;
Mycoplasma hyopneumoniae|Rep: Putative uncharacterized
protein - Mycoplasma hyopneumoniae (strain J / ATCC
25934 / NCTC 10110)
Length = 521
Score = 34.7 bits (76), Expect = 7.3
Identities = 24/101 (23%), Positives = 54/101 (53%), Gaps = 10/101 (9%)
Query: 60 NTTTVKRARSQTDRRQSTFARTMQSRDIHLSML-PDLSENLSNEERSWEEIM----QIKA 114
N++ + +T +TF +T+ +DI ++ L ++ + L +++ +I+ +IKA
Sbjct: 87 NSSLKSENQKETANLNTTFTQTISKKDIEITNLRNEIGKFLDEKDKMRSDILANDDEIKA 146
Query: 115 LPVPMSQKIELKARLQNA-----TKLRLQGFEQLHLRQRKV 150
+ +SQ E A LQN + L+L+ ++++ + RK+
Sbjct: 147 MRSEISQLKEANANLQNVKLEEISNLKLEHKDEINEKDRKI 187
>UniRef50_Q0IN30 Cluster: Os12g0511100 protein; n=1; Oryza sativa
(japonica cultivar-group)|Rep: Os12g0511100 protein -
Oryza sativa subsp. japonica (Rice)
Length = 314
Score = 34.7 bits (76), Expect = 7.3
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 16 EGWEEAGGEFYQELYPGGEQELFDNLQRADAAKLATLLPSKQARNTTTVKRARSQTDRRQ 75
+G EEA G +E G+ E +R + + P +AR V+R + + DR+Q
Sbjct: 186 KGAEEARGRGGEERPRRGQPEAESERERERRGRRGSRQPPARARRRRRVRRRQQRQDRQQ 245
Query: 76 STFARTMQSRDIH 88
+ +Q R H
Sbjct: 246 RVLGKVLQHRPRH 258
>UniRef50_A0EAM4 Cluster: Chromosome undetermined scaffold_86, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_86,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 357
Score = 34.7 bits (76), Expect = 7.3
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Query: 503 IYLYISTNGIVCAKHNTDTTKLECWETYVGQQFYKLILTD---FAV-----QFVTTFLIN 554
+ +YI G KH D +L+ ET ++ Y+ L D F V +F+ + +N
Sbjct: 265 VSIYIDEEGNTYQKHEEDYFRLKI-ETSHSEECYQFYLEDNLEFLVFCRAKKFINIYSVN 323
Query: 555 LPRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVY 588
L F R + L + + F++ ++L I+Y
Sbjct: 324 LLNEFKMERRRDKLLTLILQSRFWILSYILCIMY 357
>UniRef50_UPI00006CB0B4 Cluster: hypothetical protein TTHERM_00242340;
n=1; Tetrahymena thermophila SB210|Rep: hypothetical
protein TTHERM_00242340 - Tetrahymena thermophila SB210
Length = 1624
Score = 34.3 bits (75), Expect = 9.7
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 30 YPGGEQELFDNLQRADAAKLATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHL 89
Y G Q L L++ D KL L+ +QARNT + +++Q+ +++D++
Sbjct: 984 YEGDIQNLLTQLKQLDQ-KLQELVNQRQARNTKNMLSSKNQSQSDSKLIDNYEKNKDVNH 1042
Query: 90 SMLPDLSENLSNEERSWEEI 109
+ D S S ++S E+
Sbjct: 1043 ENIFDQSRKHSTAQKSLMEL 1062
>UniRef50_A0C7P7 Cluster: Chromosome undetermined scaffold_156, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_156, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2354
Score = 34.3 bits (75), Expect = 9.7
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 31 PGGEQ--ELFDNLQRADAAKLATLLPSKQARNTTTVKRARS-QTDRRQSTFARTMQSRDI 87
P G+Q +LFDN++ AD+ K L K +N VK +S Q + F T+Q +
Sbjct: 1841 PLGDQFGDLFDNMKVADSQKNVDDLMPKSPQN--NVKSQKSIQNNNNNHLFDSTLQQEE- 1897
Query: 88 HLSMLPDLSENLSNEERSWEEIMQ 111
+P L + + N+E+ +IMQ
Sbjct: 1898 -KIEIPKLQQLIGNQEKIETDIMQ 1920
>UniRef50_A0BXU7 Cluster: Chromosome undetermined scaffold_135,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_135,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 447
Score = 34.3 bits (75), Expect = 9.7
Identities = 25/60 (41%), Positives = 32/60 (53%), Gaps = 5/60 (8%)
Query: 273 YTYYVN-SLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTA-ARGFKQKLIESEGQFYKY 330
YT Y N S +T++F N+P L P S L A T+ A GFK+ +IE E Q Y Y
Sbjct: 270 YTNYSNKSQLNTEIFQNIPNKNTLQPPS---LQATAFRNTSSAMGFKKIVIEPERQLYSY 326
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.324 0.137 0.414
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 596,148,608
Number of Sequences: 1657284
Number of extensions: 22398009
Number of successful extensions: 71540
Number of sequences better than 10.0: 68
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 71291
Number of HSP's gapped (non-prelim): 154
length of query: 612
length of database: 575,637,011
effective HSP length: 105
effective length of query: 507
effective length of database: 401,622,191
effective search space: 203622450837
effective search space used: 203622450837
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 75 (34.3 bits)
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