Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000078-TA|BGIBMGA000078-PA|IPR012496|TMC
(612 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC036205-1|AAH36205.1| 723|Homo sapiens transmembrane channel-l... 231 5e-60
AY263165-1|AAP78780.1| 723|Homo sapiens TMC7 protein protein. 231 5e-60
AY236498-1|AAP69876.1| 723|Homo sapiens transmembrane channel-l... 231 5e-60
BC047719-1|AAH47719.1| 723|Homo sapiens transmembrane channel-l... 228 5e-59
BC141865-1|AAI41866.1| 726|Homo sapiens transmembrane channel-l... 128 4e-29
BC110296-1|AAI10297.1| 726|Homo sapiens transmembrane channel-l... 128 4e-29
AY236500-1|AAP69878.1| 726|Homo sapiens transmembrane channel-l... 128 4e-29
AY099358-1|AAM44454.1| 726|Homo sapiens large EVER2 protein pro... 128 4e-29
AY057380-1|AAL25837.1| 726|Homo sapiens EVIN2 protein. 128 4e-29
AK090478-1|BAC03459.1| 782|Homo sapiens FLJ00400 protein protein. 128 4e-29
BC025323-1|AAH25323.1| 706|Homo sapiens transmembrane channel-l... 116 2e-25
AY236492-1|AAP69870.1| 712|Homo sapiens transmembrane channel-l... 116 3e-25
AY263166-1|AAP78781.1| 706|Homo sapiens TMC4 protein protein. 115 6e-25
AK024893-1|BAB15032.1| 402|Homo sapiens protein ( Homo sapiens ... 109 3e-23
BC027602-1|AAH27602.1| 760|Homo sapiens transmembrane channel-l... 100 1e-20
AY263164-1|AAP78779.1| 760|Homo sapiens TMC5 protein protein. 100 1e-20
AY236494-1|AAP69872.1| 760|Homo sapiens transmembrane channel-l... 100 1e-20
BC038118-1|AAH38118.1| 647|Homo sapiens TMC5 protein protein. 100 2e-20
AY358155-1|AAQ88522.1| 948|Homo sapiens SAYY8238 protein. 99 2e-20
AY099359-1|AAM44455.1| 503|Homo sapiens small EVER2 protein pro... 95 5e-19
AY263163-1|AAP78778.1| 1129|Homo sapiens TMC3 protein protein. 82 5e-15
BC132679-1|AAI32680.1| 1100|Homo sapiens transmembrane channel-l... 82 6e-15
AY236490-1|AAP69868.1| 724|Homo sapiens transmembrane channel-l... 82 6e-15
AL591662-1|CAH72029.1| 760|Homo sapiens transmembrane channel-l... 78 8e-14
AL590662-1|CAI15164.1| 760|Homo sapiens transmembrane channel-l... 78 8e-14
AL162416-1|CAH72129.1| 760|Homo sapiens transmembrane channel-l... 78 8e-14
AF417578-1|AAL86399.1| 760|Homo sapiens transmembrane channel-l... 78 8e-14
BC141860-1|AAI41861.1| 739|Homo sapiens Unknown (protein for IM... 73 2e-12
BC114380-1|AAI14381.1| 740|Homo sapiens TMC1 protein protein. 73 2e-12
BC103956-1|AAI03957.1| 727|Homo sapiens TMC1 protein protein. 73 2e-12
AK023655-1|BAB14629.1| 330|Homo sapiens protein ( Homo sapiens ... 70 2e-11
AL049712-6|CAI22420.2| 906|Homo sapiens transmembrane channel-l... 69 5e-11
AF417580-1|AAL86401.2| 906|Homo sapiens transmembrane channel-l... 69 5e-11
BC032477-1|AAH32477.1| 294|Homo sapiens TMC4 protein protein. 68 1e-10
BC103955-1|AAI03956.1| 554|Homo sapiens TMC1 protein protein. 66 5e-10
BC035648-1|AAH35648.1| 444|Homo sapiens TMC6 protein protein. 50 2e-05
BC023597-1|AAH23597.1| 805|Homo sapiens transmembrane channel-l... 50 2e-05
BC018346-1|AAH18346.2| 513|Homo sapiens TMC6 protein protein. 50 2e-05
AY099356-1|AAM44452.1| 805|Homo sapiens large EVER1 protein pro... 50 2e-05
AY057379-1|AAL25836.1| 805|Homo sapiens EVIN1 protein. 50 2e-05
AK074065-1|BAB84891.1| 811|Homo sapiens FLJ00136 protein protein. 50 2e-05
AB002405-1|BAA24179.2| 444|Homo sapiens LAK-4p protein. 50 2e-05
AY236496-1|AAP69874.1| 805|Homo sapiens transmembrane channel-l... 47 2e-04
AK021738-1|BAB13884.1| 298|Homo sapiens protein ( Homo sapiens ... 46 5e-04
AY099357-1|AAM44453.1| 454|Homo sapiens small EVER1 protein pro... 45 0.001
BC028076-1|AAH28076.1| 287|Homo sapiens TMC8 protein protein. 41 0.011
AK094789-1|BAC04423.1| 205|Homo sapiens protein ( Homo sapiens ... 39 0.059
BC007766-1|AAH07766.1| 211|Homo sapiens TMC6 protein protein. 34 1.3
X90824-1|CAA62339.1| 292|Homo sapiens USF2a, USF2b protein prot... 33 3.9
BC069194-1|AAH69194.1| 1118|Homo sapiens PHLDB2 protein protein. 32 5.2
AL359963-2|CAH71092.1| 900|Homo sapiens erythrocyte membrane pr... 32 5.2
AL358815-2|CAI15129.1| 900|Homo sapiens erythrocyte membrane pr... 32 5.2
AK125555-1|BAC86200.1| 373|Homo sapiens protein ( Homo sapiens ... 32 5.2
AK096151-1|BAC04713.1| 745|Homo sapiens protein ( Homo sapiens ... 32 5.2
AK092996-1|BAC04014.1| 787|Homo sapiens protein ( Homo sapiens ... 32 5.2
AF506820-1|AAM33634.1| 1210|Homo sapiens hypothetical protein pr... 32 5.2
AF153416-1|AAG43366.1| 913|Homo sapiens FERM-containing protein... 32 5.2
AB209903-1|BAD93140.1| 1259|Homo sapiens LL5 beta protein varian... 32 5.2
AB209187-1|BAD92424.1| 603|Homo sapiens erythrocyte membrane pr... 32 5.2
AJ496194-1|CAD42711.1| 1253|Homo sapiens LL5 beta protein protein. 32 6.8
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 32 6.8
AM183303-1|CAJ66088.1| 418|Homo sapiens autogenous vein graft r... 31 9.0
>BC036205-1|AAH36205.1| 723|Homo sapiens transmembrane channel-like
7 protein.
Length = 723
Score = 231 bits (565), Expect = 5e-60
Identities = 161/544 (29%), Positives = 249/544 (45%), Gaps = 40/544 (7%)
Query: 63 TVKRARSQTDRRQSTFARTMQSRDIHLSMLPD-LSENLSNEERSWEEIMQIKALPVPMSQ 121
++ R R+ R ++ D + S L D ++ENLS+ ++ + +S+
Sbjct: 48 SIARRRTTVHSRDKQSGTLLKPTDSYSSQLEDRIAENLSSHS--------LRNYALNISE 99
Query: 122 KIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGT 181
K L+ +Q L ++Q K W RF E + LELW+ +R IEGKFGT
Sbjct: 100 KRRLRD-IQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGT 158
Query: 182 GVVSYXXXXXXXXXXXXTISILVIVFLILPKTL----LTERVYECDETEANSTVCCSIAY 237
G+ SY I +++ + ++LP L +T + + C
Sbjct: 159 GIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPV 218
Query: 238 FEKNTTNS-NIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILV 296
+ +D++ GTG++E T LFYG YT ++ + Y++P+AY+L
Sbjct: 219 SSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYT-------IDEVKFQNFTYDLPLAYLLS 271
Query: 297 PISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALY 356
I+ LSL+ IVK + GFK LI SE F YCN +F GWDFCI N A +KH +L
Sbjct: 272 TIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLR 331
Query: 357 NEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERL 416
E++ +EEER++++ R+ E I ++ R A + IYVA FS E +
Sbjct: 332 YELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHM 391
Query: 417 NESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYM 476
+ I M F EN+ + +LP I I + N I P IF+ +IRYE Y
Sbjct: 392 KKEIDK--------------MVFG--ENLFILYLPSIVITLANFITPMIFAKIIRYEDYS 435
Query: 477 PPHXXXXXXXXXXXXXXXXXXXXXXQIYLYI-STNGIVCAKHNTDTTKLECWETYVGQQF 535
P + I S + C + CWET VGQ+
Sbjct: 436 PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEM 495
Query: 536 YKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCLKMFGEQEFYLPKHVLDIVYVQTIIW 594
YKL++ DF + T ++ PR + + S + ++ +G+QEF +P +VL IVY QTI W
Sbjct: 496 YKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICW 555
Query: 595 MAMF 598
+ F
Sbjct: 556 IGAF 559
>AY263165-1|AAP78780.1| 723|Homo sapiens TMC7 protein protein.
Length = 723
Score = 231 bits (565), Expect = 5e-60
Identities = 161/544 (29%), Positives = 249/544 (45%), Gaps = 40/544 (7%)
Query: 63 TVKRARSQTDRRQSTFARTMQSRDIHLSMLPD-LSENLSNEERSWEEIMQIKALPVPMSQ 121
++ R R+ R ++ D + S L D ++ENLS+ ++ + +S+
Sbjct: 48 SIARRRTTVHSRDKQSGTLLKPTDSYSSQLEDRIAENLSSHS--------LRNYALNISE 99
Query: 122 KIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGT 181
K L+ +Q L ++Q K W RF E + LELW+ +R IEGKFGT
Sbjct: 100 KRRLRD-IQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGT 158
Query: 182 GVVSYXXXXXXXXXXXXTISILVIVFLILPKTL----LTERVYECDETEANSTVCCSIAY 237
G+ SY I +++ + ++LP L +T + + C
Sbjct: 159 GIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPV 218
Query: 238 FEKNTTNS-NIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILV 296
+ +D++ GTG++E T LFYG YT ++ + Y++P+AY+L
Sbjct: 219 SSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYT-------IDEVKFQNFTYDLPLAYLLS 271
Query: 297 PISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALY 356
I+ LSL+ IVK + GFK LI SE F YCN +F GWDFCI N A +KH +L
Sbjct: 272 TIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLR 331
Query: 357 NEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERL 416
E++ +EEER++++ R+ E I ++ R A + IYVA FS E +
Sbjct: 332 YELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHM 391
Query: 417 NESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYM 476
+ I M F EN+ + +LP I I + N I P IF+ +IRYE Y
Sbjct: 392 KKEIDK--------------MVFG--ENLFILYLPSIVITLANFITPMIFAKIIRYEDYS 435
Query: 477 PPHXXXXXXXXXXXXXXXXXXXXXXQIYLYI-STNGIVCAKHNTDTTKLECWETYVGQQF 535
P + I S + C + CWET VGQ+
Sbjct: 436 PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEM 495
Query: 536 YKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCLKMFGEQEFYLPKHVLDIVYVQTIIW 594
YKL++ DF + T ++ PR + + S + ++ +G+QEF +P +VL IVY QTI W
Sbjct: 496 YKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICW 555
Query: 595 MAMF 598
+ F
Sbjct: 556 IGAF 559
>AY236498-1|AAP69876.1| 723|Homo sapiens transmembrane channel-like
protein 7 protein.
Length = 723
Score = 231 bits (565), Expect = 5e-60
Identities = 161/544 (29%), Positives = 249/544 (45%), Gaps = 40/544 (7%)
Query: 63 TVKRARSQTDRRQSTFARTMQSRDIHLSMLPD-LSENLSNEERSWEEIMQIKALPVPMSQ 121
++ R R+ R ++ D + S L D ++ENLS+ ++ + +S+
Sbjct: 48 SIARRRTTVHSRDKQSGTLLKPTDSYSSQLEDRIAENLSSHS--------LRNYALNISE 99
Query: 122 KIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGT 181
K L+ +Q L ++Q K W RF E + LELW+ +R IEGKFGT
Sbjct: 100 KRRLRD-IQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGT 158
Query: 182 GVVSYXXXXXXXXXXXXTISILVIVFLILPKTL----LTERVYECDETEANSTVCCSIAY 237
G+ SY I +++ + ++LP L +T + + C
Sbjct: 159 GIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPV 218
Query: 238 FEKNTTNS-NIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILV 296
+ +D++ GTG++E T LFYG YT ++ + Y++P+AY+L
Sbjct: 219 SSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYT-------IDGVKFQNFTYDLPLAYLLS 271
Query: 297 PISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALY 356
I+ LSL+ IVK + GFK LI SE F YCN +F GWDFCI N A +KH +L
Sbjct: 272 TIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLR 331
Query: 357 NEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERL 416
E++ +EEER++++ R+ E I ++ R A + IYVA FS E +
Sbjct: 332 YELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHM 391
Query: 417 NESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYM 476
+ I M F EN+ + +LP I I + N I P IF+ +IRYE Y
Sbjct: 392 KKEIDK--------------MVFG--ENLFILYLPSIVITLANFITPMIFAKIIRYEDYS 435
Query: 477 PPHXXXXXXXXXXXXXXXXXXXXXXQIYLYI-STNGIVCAKHNTDTTKLECWETYVGQQF 535
P + I S + C + CWET VGQ+
Sbjct: 436 PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEM 495
Query: 536 YKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCLKMFGEQEFYLPKHVLDIVYVQTIIW 594
YKL++ DF + T ++ PR + + S + ++ +G+QEF +P +VL IVY QTI W
Sbjct: 496 YKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICW 555
Query: 595 MAMF 598
+ F
Sbjct: 556 IGAF 559
>BC047719-1|AAH47719.1| 723|Homo sapiens transmembrane channel-like
7 protein.
Length = 723
Score = 228 bits (557), Expect = 5e-59
Identities = 160/544 (29%), Positives = 248/544 (45%), Gaps = 40/544 (7%)
Query: 63 TVKRARSQTDRRQSTFARTMQSRDIHLSMLPD-LSENLSNEERSWEEIMQIKALPVPMSQ 121
++ R R+ ++ D + S L D ++ENLS+ ++ + +S+
Sbjct: 48 SIARRRTTVHSWDKQSGTLLKPTDSYSSQLEDRIAENLSSHS--------LRNYALNISE 99
Query: 122 KIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGT 181
K L+ +Q L ++Q K W RF E + LELW+ +R IEGKFGT
Sbjct: 100 KRRLRD-IQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGT 158
Query: 182 GVVSYXXXXXXXXXXXXTISILVIVFLILPKTL----LTERVYECDETEANSTVCCSIAY 237
G+ SY I +++ + ++LP L +T + + C
Sbjct: 159 GIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPV 218
Query: 238 FEKNTTNS-NIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILV 296
+ +D++ GTG++E T LFYG YT ++ + Y++P+AY+L
Sbjct: 219 SSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYT-------IDGVKFQNFTYDLPLAYLLS 271
Query: 297 PISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALY 356
I+ LSL+ IVK + GFK LI SE F YCN +F GWDFCI N A +KH +L
Sbjct: 272 TIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLR 331
Query: 357 NEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERL 416
E++ +EEER++++ R+ E I ++ R A + IYVA FS E +
Sbjct: 332 YELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHM 391
Query: 417 NESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYM 476
+ I M F EN+ + +LP I I + N I P IF+ +IRYE Y
Sbjct: 392 KKEIDK--------------MVFG--ENLFILYLPSIVITLANFITPMIFAKIIRYEDYS 435
Query: 477 PPHXXXXXXXXXXXXXXXXXXXXXXQIYLYI-STNGIVCAKHNTDTTKLECWETYVGQQF 535
P + I S + C + CWET VGQ+
Sbjct: 436 PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEM 495
Query: 536 YKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCLKMFGEQEFYLPKHVLDIVYVQTIIW 594
YKL++ DF + T ++ PR + + S + ++ +G+QEF +P +VL IVY QTI W
Sbjct: 496 YKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICW 555
Query: 595 MAMF 598
+ F
Sbjct: 556 IGAF 559
>BC141865-1|AAI41866.1| 726|Homo sapiens transmembrane channel-like
8 protein.
Length = 726
Score = 128 bits (310), Expect = 4e-29
Identities = 119/492 (24%), Positives = 193/492 (39%), Gaps = 42/492 (8%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LP M K L +L+ ++ +++ R++ V R R L LW+
Sbjct: 36 VRGLPYAMMDK-RLIWQLREPVGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA 94
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ EI G FGTG+ SY +L F++LP L R + T +
Sbjct: 95 LYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWL--RPPDPGPTLNLTLQ 152
Query: 232 CCSIAYFEKNTTN-SNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMP 290
C N V+ G + T LFYG Y V + Y++
Sbjct: 153 CPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYR-------VGP--ESSSVYSIR 202
Query: 291 MAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARI 350
+AY+L P++ LL ++ +G QK + +G VF WDFCI +A I
Sbjct: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262
Query: 351 KHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFN 410
K + NE K +EE R + Q ++R L + I+ A
Sbjct: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322
Query: 411 FSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMI 470
+S + ES+ +L+++LP I ++N + P +F++++
Sbjct: 323 YSQDNKEESLF-----------------------LLLQYLPPGVIALVNFLGPLLFTFLV 359
Query: 471 RYEGYMPPHXXXXXXXX----XXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLEC 526
+ E Y PP+ Q L I + C + + +C
Sbjct: 360 QLENY-PPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQC 418
Query: 527 WETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDI 586
WE VG++ YKL + +F + FL+ LPR + R +EF +PK+VLDI
Sbjct: 419 WENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDI 478
Query: 587 VYVQTIIWMAMF 598
V QT+ WM +F
Sbjct: 479 VAGQTVTWMGLF 490
>BC110296-1|AAI10297.1| 726|Homo sapiens transmembrane channel-like
8 protein.
Length = 726
Score = 128 bits (310), Expect = 4e-29
Identities = 119/492 (24%), Positives = 193/492 (39%), Gaps = 42/492 (8%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LP M K L +L+ ++ +++ R++ V R R L LW+
Sbjct: 36 VRGLPYAMMDK-RLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA 94
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ EI G FGTG+ SY +L F++LP L R + T +
Sbjct: 95 LYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWL--RPPDPGPTLNLTLQ 152
Query: 232 CCSIAYFEKNTTN-SNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMP 290
C N V+ G + T LFYG Y V + Y++
Sbjct: 153 CPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYR-------VGP--ESSSVYSIR 202
Query: 291 MAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARI 350
+AY+L P++ LL ++ +G QK + +G VF WDFCI +A I
Sbjct: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262
Query: 351 KHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFN 410
K + NE K +EE R + Q ++R L + I+ A
Sbjct: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322
Query: 411 FSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMI 470
+S + ES+ +L+++LP I ++N + P +F++++
Sbjct: 323 YSQDNKEESLF-----------------------LLLQYLPPGVIALVNFLGPLLFTFLV 359
Query: 471 RYEGYMPPHXXXXXXXX----XXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLEC 526
+ E Y PP+ Q L I + C + + +C
Sbjct: 360 QLENY-PPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQC 418
Query: 527 WETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDI 586
WE VG++ YKL + +F + FL+ LPR + R +EF +PK+VLDI
Sbjct: 419 WENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDI 478
Query: 587 VYVQTIIWMAMF 598
V QT+ WM +F
Sbjct: 479 VAGQTVTWMGLF 490
>AY236500-1|AAP69878.1| 726|Homo sapiens transmembrane channel-like
protein 8 protein.
Length = 726
Score = 128 bits (310), Expect = 4e-29
Identities = 119/492 (24%), Positives = 193/492 (39%), Gaps = 42/492 (8%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LP M K L +L+ ++ +++ R++ V R R L LW+
Sbjct: 36 VRGLPYAMMDK-RLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA 94
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ EI G FGTG+ SY +L F++LP L R + T +
Sbjct: 95 LYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWL--RPPDPGPTLNLTLQ 152
Query: 232 CCSIAYFEKNTTN-SNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMP 290
C N V+ G + T LFYG Y V + Y++
Sbjct: 153 CPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYR-------VGP--ESSSVYSIR 202
Query: 291 MAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARI 350
+AY+L P++ LL ++ +G QK + +G VF WDFCI +A I
Sbjct: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262
Query: 351 KHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFN 410
K + NE K +EE R + Q ++R L + I+ A
Sbjct: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322
Query: 411 FSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMI 470
+S + ES+ +L+++LP I ++N + P +F++++
Sbjct: 323 YSQDNKEESLF-----------------------LLLQYLPPGVIALVNFLGPLLFTFLV 359
Query: 471 RYEGYMPPHXXXXXXXX----XXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLEC 526
+ E Y PP+ Q L I + C + + +C
Sbjct: 360 QLENY-PPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQC 418
Query: 527 WETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDI 586
WE VG++ YKL + +F + FL+ LPR + R +EF +PK+VLDI
Sbjct: 419 WENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDI 478
Query: 587 VYVQTIIWMAMF 598
V QT+ WM +F
Sbjct: 479 VAGQTVTWMGLF 490
>AY099358-1|AAM44454.1| 726|Homo sapiens large EVER2 protein
protein.
Length = 726
Score = 128 bits (310), Expect = 4e-29
Identities = 119/492 (24%), Positives = 193/492 (39%), Gaps = 42/492 (8%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LP M K L +L+ ++ +++ R++ V R R L LW+
Sbjct: 36 VRGLPYAMMDK-RLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA 94
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ EI G FGTG+ SY +L F++LP L R + T +
Sbjct: 95 LYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWL--RPPDPGPTLNLTLQ 152
Query: 232 CCSIAYFEKNTTN-SNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMP 290
C N V+ G + T LFYG Y V + Y++
Sbjct: 153 CPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYR-------VGP--ESSSVYSIR 202
Query: 291 MAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARI 350
+AY+L P++ LL ++ +G QK + +G VF WDFCI +A I
Sbjct: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262
Query: 351 KHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFN 410
K + NE K +EE R + Q ++R L + I+ A
Sbjct: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322
Query: 411 FSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMI 470
+S + ES+ +L+++LP I ++N + P +F++++
Sbjct: 323 YSQDNKEESLF-----------------------LLLQYLPPGVIALVNFLGPLLFTFLV 359
Query: 471 RYEGYMPPHXXXXXXXX----XXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLEC 526
+ E Y PP+ Q L I + C + + +C
Sbjct: 360 QLENY-PPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQC 418
Query: 527 WETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDI 586
WE VG++ YKL + +F + FL+ LPR + R +EF +PK+VLDI
Sbjct: 419 WENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDI 478
Query: 587 VYVQTIIWMAMF 598
V QT+ WM +F
Sbjct: 479 VAGQTVTWMGLF 490
>AY057380-1|AAL25837.1| 726|Homo sapiens EVIN2 protein.
Length = 726
Score = 128 bits (310), Expect = 4e-29
Identities = 119/492 (24%), Positives = 193/492 (39%), Gaps = 42/492 (8%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LP M K L +L+ ++ +++ R++ V R R L LW+
Sbjct: 36 VRGLPYAMMDK-RLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA 94
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ EI G FGTG+ SY +L F++LP L R + T +
Sbjct: 95 LYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWL--RPPDPGPTLNLTLQ 152
Query: 232 CCSIAYFEKNTTN-SNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMP 290
C N V+ G + T LFYG Y V + Y++
Sbjct: 153 CPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYR-------VGP--ESSSVYSIR 202
Query: 291 MAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARI 350
+AY+L P++ LL ++ +G QK + +G VF WDFCI +A I
Sbjct: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262
Query: 351 KHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFN 410
K + NE K +EE R + Q ++R L + I+ A
Sbjct: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322
Query: 411 FSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMI 470
+S + ES+ +L+++LP I ++N + P +F++++
Sbjct: 323 YSQDNKEESLF-----------------------LLLQYLPPGVIALVNFLGPLLFTFLV 359
Query: 471 RYEGYMPPHXXXXXXXX----XXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLEC 526
+ E Y PP+ Q L I + C + + +C
Sbjct: 360 QLENY-PPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQC 418
Query: 527 WETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDI 586
WE VG++ YKL + +F + FL+ LPR + R +EF +PK+VLDI
Sbjct: 419 WENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDI 478
Query: 587 VYVQTIIWMAMF 598
V QT+ WM +F
Sbjct: 479 VAGQTVTWMGLF 490
>AK090478-1|BAC03459.1| 782|Homo sapiens FLJ00400 protein protein.
Length = 782
Score = 128 bits (310), Expect = 4e-29
Identities = 119/492 (24%), Positives = 193/492 (39%), Gaps = 42/492 (8%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LP M K L +L+ ++ +++ R++ V R R L LW+
Sbjct: 92 VRGLPYAMMDK-RLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA 150
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ EI G FGTG+ SY +L F++LP L R + T +
Sbjct: 151 LYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWL--RPPDPGPTLNLTLQ 208
Query: 232 CCSIAYFEKNTTN-SNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMP 290
C N V+ G + T LFYG Y V + Y++
Sbjct: 209 CPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYR-------VGP--ESSSVYSIR 258
Query: 291 MAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARI 350
+AY+L P++ LL ++ +G QK + +G VF WDFCI +A I
Sbjct: 259 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 318
Query: 351 KHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFN 410
K + NE K +EE R + Q ++R L + I+ A
Sbjct: 319 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLIGLLVVGAISAIFWATK 378
Query: 411 FSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMI 470
+S + ES+ +L+++LP I ++N + P +F++++
Sbjct: 379 YSQDNKEESLF-----------------------LLLQYLPPGVIALVNFLGPLLFTFLV 415
Query: 471 RYEGYMPPHXXXXXXXX----XXXXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLEC 526
+ E Y PP+ Q L I + C + + +C
Sbjct: 416 QLENY-PPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQC 474
Query: 527 WETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDI 586
WE VG++ YKL + +F + FL+ LPR + R +EF +PK+VLDI
Sbjct: 475 WENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDI 534
Query: 587 VYVQTIIWMAMF 598
V QT+ WM +F
Sbjct: 535 VAGQTVTWMGLF 546
>BC025323-1|AAH25323.1| 706|Homo sapiens transmembrane channel-like
4 protein.
Length = 706
Score = 116 bits (280), Expect = 2e-25
Identities = 103/457 (22%), Positives = 177/457 (38%), Gaps = 36/457 (7%)
Query: 146 RQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVI 205
R ++ R + E L+ W ++ I G+FG G SY S+L+
Sbjct: 117 RWARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMA 176
Query: 206 VFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFY 265
+LP T L + +S + + T + +++ G G++E + LFY
Sbjct: 177 CMTLLP-TWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFY 235
Query: 266 GVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEG 325
G Y + + + Y+ + L+ L+ I+ + G KQ L+
Sbjct: 236 GFYPPRP---------------RLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESE 280
Query: 326 QFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
Y + VF WDF + D R++ + + E+K +EE ++ + R+ Q + L
Sbjct: 281 ALTSYSHRVFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWL 340
Query: 386 KRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENV 445
R A+ + +Y A + E L E MP+V L +
Sbjct: 341 VRVLLNLLVVALLGAAFYGVYWATGCTVE-LQE-----------MPLVQEL----PLLKL 384
Query: 446 LMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYL 505
+ +LP I I +N ++P +F + EGY ++
Sbjct: 385 GVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFLRLASLVVLLFSLWN 444
Query: 506 YISTNGIV----CAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMA 561
I+ G C + +L CWET +GQ+ YKL+L D LI PR +
Sbjct: 445 QITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLC 504
Query: 562 RHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
++ G QEF +P VL ++Y QT++W+ F
Sbjct: 505 GLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSF 541
>AY236492-1|AAP69870.1| 712|Homo sapiens transmembrane channel-like
protein 4 protein.
Length = 712
Score = 116 bits (278), Expect = 3e-25
Identities = 103/457 (22%), Positives = 177/457 (38%), Gaps = 36/457 (7%)
Query: 146 RQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVI 205
R ++ R + E L+ W ++ I G+FG G SY S+L+
Sbjct: 123 RWARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMA 182
Query: 206 VFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFY 265
+LP T L + +S + + T + +++ G G++E + LFY
Sbjct: 183 CMTLLP-TWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFY 241
Query: 266 GVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEG 325
G Y + + + Y+ + L+ L+ I+ + G KQ L+
Sbjct: 242 GFYPPRP---------------RLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESE 286
Query: 326 QFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
Y + VF WDF + D R++ + + E+K +EE ++ + R+ Q + L
Sbjct: 287 ALTSYSHRVFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWL 346
Query: 386 KRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENV 445
R A+ + +Y A + E L E MP+V L +
Sbjct: 347 VRVLLNLLVVALLGAAFYGVYWATGCTVE-LQE-----------MPLVQEL----PLLKL 390
Query: 446 LMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYL 505
+ +LP I I +N ++P +F + EGY ++
Sbjct: 391 GVNYLPPIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFLRLASLVVLLFSLWN 450
Query: 506 YISTNGIV----CAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMA 561
I+ G C + +L CWET +GQ+ YKL+L D LI PR +
Sbjct: 451 QITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLC 510
Query: 562 RHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
++ G QEF +P VL ++Y QT++W+ F
Sbjct: 511 GLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSF 547
>AY263166-1|AAP78781.1| 706|Homo sapiens TMC4 protein protein.
Length = 706
Score = 115 bits (276), Expect = 6e-25
Identities = 102/457 (22%), Positives = 177/457 (38%), Gaps = 36/457 (7%)
Query: 146 RQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVI 205
R ++ R + E L+ W ++ I G+FG G SY S+L+
Sbjct: 117 RWARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMA 176
Query: 206 VFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFY 265
+LP T L + +S + + T + +++ G G++E + LFY
Sbjct: 177 CMTLLP-TWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFY 235
Query: 266 GVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEG 325
G Y + + + Y+ + L+ L+ I+ + G KQ L+
Sbjct: 236 GFYPPRP---------------RLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESE 280
Query: 326 QFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
Y + VF WDF + D R++ + + E++ +EE ++ + R+ Q + L
Sbjct: 281 ALTSYSHRVFSAWDFGLCGDVHVRLRQRIILYELQVELEETVVRRQAAVRTLGQQARVWL 340
Query: 386 KRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENV 445
R A+ + +Y A + E L E MP+V L +
Sbjct: 341 VRVLLNLLVVALLGAAFYGVYWATGCTVE-LQE-----------MPLVQEL----PLLKL 384
Query: 446 LMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYL 505
+ +LP I I +N ++P +F + EGY ++
Sbjct: 385 GVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFLRLASLVVLLFSLWN 444
Query: 506 YISTNGIV----CAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMA 561
I+ G C + +L CWET +GQ+ YKL+L D LI PR +
Sbjct: 445 QITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLC 504
Query: 562 RHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
++ G QEF +P VL ++Y QT++W+ F
Sbjct: 505 GLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSF 541
>AK024893-1|BAB15032.1| 402|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21240 fis, clone COL01132. ).
Length = 402
Score = 109 bits (262), Expect = 3e-23
Identities = 75/253 (29%), Positives = 115/253 (45%), Gaps = 18/253 (7%)
Query: 348 ARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYV 407
A +KH +L E++ +EEER++++ R+ E I ++ R A + IYV
Sbjct: 2 ADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYV 61
Query: 408 AFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFS 467
A FS E + + I M F EN+ + +LP I I + N I P IF+
Sbjct: 62 ATVFSQEHMKKEIDK--------------MVFG--ENLFILYLPSIVITLANFITPMIFA 105
Query: 468 YMIRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIYLYI-STNGIVCAKHNTDTTKLEC 526
+IRYE Y P + I S + C + C
Sbjct: 106 KIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPC 165
Query: 527 WETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRS-RCLKMFGEQEFYLPKHVLD 585
WET VGQ+ YKL++ DF + T ++ PR + + S + ++ +G+QEF +P +VL
Sbjct: 166 WETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLG 225
Query: 586 IVYVQTIIWMAMF 598
IVY QTI W+ F
Sbjct: 226 IVYGQTICWIGAF 238
>BC027602-1|AAH27602.1| 760|Homo sapiens transmembrane channel-like
5 protein.
Length = 760
Score = 100 bits (240), Expect = 1e-20
Identities = 123/523 (23%), Positives = 216/523 (41%), Gaps = 82/523 (15%)
Query: 81 TMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKIELKARLQNATKLRLQGF 140
T+Q + + S++P S + R+ M+ K + + ++ + Q L+L
Sbjct: 101 TVQGQKLIASLIPMTSRDRIKAIRNQPRTMEEKR---NLRKIVDKEKSKQTHRILQLNCC 157
Query: 141 EQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTI 200
Q + + R + +E + + LWQ ++ I GKFGT V+SY
Sbjct: 158 IQCLNSISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFS 217
Query: 201 SILVIVFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMER 260
IL F+I+P+ + + KNT L+ G G+
Sbjct: 218 FILNFSFIIIPQFTVAK----------------------KNTLQFT-GLEFFTGVGYFRD 254
Query: 261 TILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKL 320
T+++YG YT+ + ++ YNM +AYI + +++ + A+ F+
Sbjct: 255 TVMYYGFYTNSTIQHG-----NSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNF 309
Query: 321 IESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQ 380
I L+F WDF + ++++ ++K + L EI+ + E R ++ S+ +Q
Sbjct: 310 INPHIYSGGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSELR---QENSKLTFNQ 365
Query: 381 ILMHLKRXXXX-XXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSF 439
+L A +Y ++ E L +T + P
Sbjct: 366 LLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFL---------KTHSNPGA------ 410
Query: 440 NQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGY-MPPHXXXXXXXXXXXXXXXXXXX 498
VL+ LPF+ + +NL +P I+S E Y MP H
Sbjct: 411 -----VLL--LPFV-VSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIR----------- 451
Query: 499 XXXQIYLYISTNGIVCAKHNTDTTKL---ECWETYVGQQFYKLILTDFAVQFVTTFLINL 555
I+L IS GI+C + +T L ECWET +GQ Y+L+L DF V +FL
Sbjct: 452 ---NIFLKISIIGILCY-YWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFL--- 504
Query: 556 PRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
F+ R + + G QEF + ++VL+++Y QT++W+ +F
Sbjct: 505 -GEFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIF 546
>AY263164-1|AAP78779.1| 760|Homo sapiens TMC5 protein protein.
Length = 760
Score = 100 bits (240), Expect = 1e-20
Identities = 123/523 (23%), Positives = 216/523 (41%), Gaps = 82/523 (15%)
Query: 81 TMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKIELKARLQNATKLRLQGF 140
T+Q + + S++P S + R+ M+ K + + ++ + Q L+L
Sbjct: 101 TVQGQKLIASLIPMTSRDRIKAIRNQPRTMEEKR---NLRKIVDKEKSKQTHRILQLNCC 157
Query: 141 EQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTI 200
Q + + R + +E + + LWQ ++ I GKFGT V+SY
Sbjct: 158 IQCLNSISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFS 217
Query: 201 SILVIVFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMER 260
IL F+I+P+ + + KNT L+ G G+
Sbjct: 218 FILNFSFIIIPQFTVAK----------------------KNTLQFT-GLEFFTGVGYFRD 254
Query: 261 TILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKL 320
T+++YG YT+ + ++ YNM +AYI + +++ + A+ F+
Sbjct: 255 TVMYYGFYTNSTIQHG-----NSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNF 309
Query: 321 IESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQ 380
I L+F WDF + ++++ ++K + L EI+ + E R ++ S+ +Q
Sbjct: 310 INPHIYSGGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSELR---QENSKLTFNQ 365
Query: 381 ILMHLKRXXXX-XXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSF 439
+L A +Y ++ E L +T + P
Sbjct: 366 LLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFL---------KTHSNPGA------ 410
Query: 440 NQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGY-MPPHXXXXXXXXXXXXXXXXXXX 498
VL+ LPF+ + +NL +P I+S E Y MP H
Sbjct: 411 -----VLL--LPFV-VSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIR----------- 451
Query: 499 XXXQIYLYISTNGIVCAKHNTDTTKL---ECWETYVGQQFYKLILTDFAVQFVTTFLINL 555
I+L IS GI+C + +T L ECWET +GQ Y+L+L DF V +FL
Sbjct: 452 ---NIFLKISIIGILCY-YWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFL--- 504
Query: 556 PRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
F+ R + + G QEF + ++VL+++Y QT++W+ +F
Sbjct: 505 -GEFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIF 546
>AY236494-1|AAP69872.1| 760|Homo sapiens transmembrane channel-like
protein 5 protein.
Length = 760
Score = 100 bits (240), Expect = 1e-20
Identities = 123/523 (23%), Positives = 216/523 (41%), Gaps = 82/523 (15%)
Query: 81 TMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKIELKARLQNATKLRLQGF 140
T+Q + + S++P S + R+ M+ K + + ++ + Q L+L
Sbjct: 101 TVQGQKLIASLIPMTSRDRIKAIRNQPRTMEEKR---NLRKIVDKEKSKQTHRILQLNCC 157
Query: 141 EQLHLRQRKVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTI 200
Q + + R + +E + + LWQ ++ I GKFGT V+SY
Sbjct: 158 IQCLNSISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFS 217
Query: 201 SILVIVFLILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMER 260
IL F+I+P+ + + KNT L+ G G+
Sbjct: 218 FILNFSFIIIPQFTVAK----------------------KNTLQFT-GLEFFTGVGYFRD 254
Query: 261 TILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKL 320
T+++YG YT+ + ++ YNM +AYI + +++ + A+ F+
Sbjct: 255 TVMYYGFYTNSTIQHG-----NSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNF 309
Query: 321 IESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQ 380
I L+F WDF + ++++ ++K + L EI+ + E R ++ S+ +Q
Sbjct: 310 INPHIYSGGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSELR---QENSKLTFNQ 365
Query: 381 ILMHLKRXXXX-XXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSF 439
+L A +Y ++ E L +T + P
Sbjct: 366 LLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFL---------KTHSNPGA------ 410
Query: 440 NQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGY-MPPHXXXXXXXXXXXXXXXXXXX 498
VL+ LPF+ + +NL +P I+S E Y MP H
Sbjct: 411 -----VLL--LPFV-VSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIR----------- 451
Query: 499 XXXQIYLYISTNGIVCAKHNTDTTKL---ECWETYVGQQFYKLILTDFAVQFVTTFLINL 555
I+L IS GI+C + +T L ECWET +GQ Y+L+L DF V +FL
Sbjct: 452 ---NIFLKISIIGILCY-YWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFL--- 504
Query: 556 PRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
F+ R + + G QEF + ++VL+++Y QT++W+ +F
Sbjct: 505 -GEFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIF 546
>BC038118-1|AAH38118.1| 647|Homo sapiens TMC5 protein protein.
Length = 647
Score = 100 bits (239), Expect = 2e-20
Identities = 111/455 (24%), Positives = 190/455 (41%), Gaps = 79/455 (17%)
Query: 149 KVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFL 208
+ + R + +E + + LWQ ++ I GKFGT V+SY IL F+
Sbjct: 53 RAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFI 112
Query: 209 ILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVY 268
I+P+ + + KNT L+ G G+ T+++YG Y
Sbjct: 113 IIPQFTVAK----------------------KNTLQFT-GLEFFTGVGYFRDTVMYYGFY 149
Query: 269 TDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFY 328
T+ + ++ YNM +AYI + +++ + A+ F+ I
Sbjct: 150 TNSTIQHG-----NSGASYNMQLAYIFTIGACLTTCFFSLLFSTAKYFRNNFINPHIYSG 204
Query: 329 KYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRX 388
L+F WDF + ++++ ++K + L EI+ + E R ++ S+ +Q+L
Sbjct: 205 GITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSELR---QENSKLTFNQLLTRFSAY 260
Query: 389 XXX-XXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLM 447
A +Y ++ E L +T + P VL+
Sbjct: 261 MVAWVVSTGVAIACCAAVYYLAEYNLEFL---------KTHSNPGA-----------VLL 300
Query: 448 EFLPFICIVVLNLIIPEIFSYMIRYEGY-MPPHXXXXXXXXXXXXXXXXXXXXXXQIYLY 506
LPF+ + +NL +P I+S E Y MP H I+L
Sbjct: 301 --LPFV-VSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIR--------------NIFLK 343
Query: 507 ISTNGIVCAKHNTDTTKL---ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARH 563
IS GI+C + +T L ECWET +GQ Y+L+L DF V +FL F+ R
Sbjct: 344 ISIIGILCY-YWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFL----GEFLRRI 398
Query: 564 TRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+ + G QEF + ++VL+++Y QT++W+ +F
Sbjct: 399 IGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIF 433
>AY358155-1|AAQ88522.1| 948|Homo sapiens SAYY8238 protein.
Length = 948
Score = 99 bits (238), Expect = 2e-20
Identities = 111/455 (24%), Positives = 190/455 (41%), Gaps = 79/455 (17%)
Query: 149 KVWHRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFL 208
+ + R + +E + + LWQ ++ I GKFGT V+SY IL F+
Sbjct: 412 RAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFI 471
Query: 209 ILPKTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVY 268
I+P+ + + KNT L+ G G+ T+++YG Y
Sbjct: 472 IIPQFTVAK----------------------KNTLQFT-GLEFFTGVGYFRDTVMYYGFY 508
Query: 269 TDQIYTYYVNSLYHTKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFY 328
T+ + ++ YNM +AYI + +++ + A+ F+ I
Sbjct: 509 TNSTIQHG-----NSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSG 563
Query: 329 KYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRX 388
L+F WDF + ++++ ++K + L EI+ + E R ++ S+ +Q+L
Sbjct: 564 GITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSELR---QENSKLTFNQLLTRFSAY 619
Query: 389 XXX-XXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIVYTTMSFNQLENVLM 447
A +Y ++ E L +T + P VL+
Sbjct: 620 MVAWVVSTGVAIACCAAVYYLAEYNLEFL---------KTHSNPGA-----------VLL 659
Query: 448 EFLPFICIVVLNLIIPEIFSYMIRYEGY-MPPHXXXXXXXXXXXXXXXXXXXXXXQIYLY 506
LPF+ + +NL +P I+S E Y MP H I+L
Sbjct: 660 --LPFV-VSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIR--------------NIFLK 702
Query: 507 ISTNGIVCAKHNTDTTKL---ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARH 563
IS GI+C + +T L ECWET +GQ Y+L+L DF V +FL F+ R
Sbjct: 703 ISIIGILCY-YWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFL----GEFLRRI 757
Query: 564 TRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+ + G QEF + ++VL+++Y QT++W+ +F
Sbjct: 758 IGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIF 792
>AY099359-1|AAM44455.1| 503|Homo sapiens small EVER2 protein
protein.
Length = 503
Score = 95.5 bits (227), Expect = 5e-19
Identities = 72/289 (24%), Positives = 116/289 (40%), Gaps = 28/289 (9%)
Query: 314 RGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQ 373
+G QK + +G VF WDFCI +A IK + NE K +EE R + Q
Sbjct: 3 KGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQ 62
Query: 374 SRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFSTERLNESIGSNENRTRTMPIV 433
++R L + I+ A +S + ES+
Sbjct: 63 QQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLF------------ 110
Query: 434 YTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYMIRYEGYMPPHXXXXXXXX----XX 489
+L+++LP I ++N + P +F+++++ E Y PP+
Sbjct: 111 -----------LLLQYLPPGVIALVNFLGPLLFTFLVQLENY-PPNTEVNLTLIWCVVLK 158
Query: 490 XXXXXXXXXXXXQIYLYISTNGIVCAKHNTDTTKLECWETYVGQQFYKLILTDFAVQFVT 549
Q L I + C + + +CWE VG++ YKL + +F +
Sbjct: 159 LASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAF 218
Query: 550 TFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
FL+ LPR + R +EF +PK+VLDIV QT+ WM +F
Sbjct: 219 AFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLF 267
>AY263163-1|AAP78778.1| 1129|Homo sapiens TMC3 protein protein.
Length = 1129
Score = 82.2 bits (194), Expect = 5e-15
Identities = 68/279 (24%), Positives = 124/279 (44%), Gaps = 27/279 (9%)
Query: 112 IKALPVPMSQKIELKARLQNAT---KLRLQGFEQLHLRQRKVWHRF-RIGCTETFSKLEL 167
I+ P M QK+ + +N + RL ++W +F R+ C +
Sbjct: 63 IRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIFIP- 121
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ +++IE FG+GV SY ++I+ F+++P+ + + + A
Sbjct: 122 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPEVIAGQPF----GSTA 177
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTG-WMERTILFYGVYTDQIYTYYVNSLYHTKLF 286
T+ K +S LD + G +++ ++LFYG YY +
Sbjct: 178 RKTI-------PKEQVSSAQDLDTVWSLGGYLQYSVLFYG--------YYGRERKIGRAG 222
Query: 287 YNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDR 346
Y +P+AY LV ++ S I ++K A+ + L + + Y +C VF WD+ I N
Sbjct: 223 YRLPLAYFLVGMAVFAYSFIILLKRMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPE 282
Query: 347 SARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
+A K A+ N I+ I EE +E+K+S++ I + +
Sbjct: 283 AAESKTAAIVNSIREAILEE--QEKKKSKNLAVTICLRI 319
Score = 51.6 bits (118), Expect = 8e-06
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 518 NTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSR-CLKM---FG 573
+T + + +CWETYVGQ+ KL + D + LI+ R R+ C + F
Sbjct: 490 HTQSPQDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFP 549
Query: 574 EQ-EFYLPKHVLDIVYVQTIIWMAMF 598
E EF + ++VL +VY Q +IWM F
Sbjct: 550 EYGEFKIAENVLHLVYNQGMIWMGAF 575
>BC132679-1|AAI32680.1| 1100|Homo sapiens transmembrane channel-like
3 protein.
Length = 1100
Score = 81.8 bits (193), Expect = 6e-15
Identities = 68/279 (24%), Positives = 124/279 (44%), Gaps = 27/279 (9%)
Query: 112 IKALPVPMSQKIELKARLQNAT---KLRLQGFEQLHLRQRKVWHRF-RIGCTETFSKLEL 167
I+ P M QK+ + +N + RL ++W +F R+ C +
Sbjct: 64 IRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIFIP- 122
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ +++IE FG+GV SY ++I+ F+++P+ + + + A
Sbjct: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPF----GSTA 178
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTG-WMERTILFYGVYTDQIYTYYVNSLYHTKLF 286
T+ K +S LD + G +++ ++LFYG YY +
Sbjct: 179 RKTI-------PKEQVSSAQDLDTVWSLGGYLQYSVLFYG--------YYGRERKIGRAG 223
Query: 287 YNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDR 346
Y +P+AY LV ++ S I ++K A+ + L + + Y +C VF WD+ I N
Sbjct: 224 YRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPE 283
Query: 347 SARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
+A K A+ N I+ I EE +E+K+S++ I + +
Sbjct: 284 AAESKTAAIVNSIREAILEE--QEKKKSKNLAVTICLRI 320
Score = 51.6 bits (118), Expect = 8e-06
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 518 NTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSR-CLKM---FG 573
+T + + +CWETYVGQ+ KL + D + LI+ R R+ C + F
Sbjct: 491 HTQSPQDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFP 550
Query: 574 EQ-EFYLPKHVLDIVYVQTIIWMAMF 598
E EF + ++VL +VY Q +IWM F
Sbjct: 551 EYGEFKIAENVLHLVYNQGMIWMGAF 576
>AY236490-1|AAP69868.1| 724|Homo sapiens transmembrane channel-like
protein 3 protein.
Length = 724
Score = 81.8 bits (193), Expect = 6e-15
Identities = 68/279 (24%), Positives = 124/279 (44%), Gaps = 27/279 (9%)
Query: 112 IKALPVPMSQKIELKARLQNAT---KLRLQGFEQLHLRQRKVWHRF-RIGCTETFSKLEL 167
I+ P M QK+ + +N + RL ++W +F R+ C +
Sbjct: 64 IRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIFIP- 122
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ +++IE FG+GV SY ++I+ F+++P+ + + + A
Sbjct: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPF----GSTA 178
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTG-WMERTILFYGVYTDQIYTYYVNSLYHTKLF 286
T+ K +S LD + G +++ ++LFYG YY +
Sbjct: 179 RKTI-------PKEQVSSAQDLDTVWSLGGYLQYSVLFYG--------YYGRERKIGRAG 223
Query: 287 YNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDR 346
Y +P+AY LV ++ S I ++K A+ + L + + Y +C VF WD+ I N
Sbjct: 224 YRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPE 283
Query: 347 SARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHL 385
+A K A+ N I+ I EE +E+K+S++ I + +
Sbjct: 284 AAESKTAAIVNSIREAILEE--QEKKKSKNLAVTICLRI 320
Score = 51.6 bits (118), Expect = 8e-06
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 518 NTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSR-CLKM---FG 573
+T + + +CWETYVGQ+ KL + D + LI+ R R+ C + F
Sbjct: 491 HTQSPQDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFP 550
Query: 574 EQ-EFYLPKHVLDIVYVQTIIWMAMF 598
E EF + ++VL +VY Q +IWM F
Sbjct: 551 EYGEFKIAENVLHLVYNQGMIWMGAF 576
>AL591662-1|CAH72029.1| 760|Homo sapiens transmembrane channel-like
1 protein.
Length = 760
Score = 78.2 bits (184), Expect = 8e-14
Identities = 121/561 (21%), Positives = 212/561 (37%), Gaps = 59/561 (10%)
Query: 65 KRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKIE 124
++AR + RR+ R + +I L L L +E+R + I +K P M +KIE
Sbjct: 64 RKAREKERRRR--LKRGAEEEEIDEEELERLKAEL-DEKR--QIIATVKCKPWKMEKKIE 118
Query: 125 LKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLEL-----------WQTPMR 173
+ L+ A K + L + K W F++ + ++K W+ ++
Sbjct: 119 V---LKEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIK 175
Query: 174 EIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTVCC 233
IE +FG+ V SY + IL ++LP+ L
Sbjct: 176 AIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAE-- 233
Query: 234 SIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAY 293
E + N + D G + ++LFYG Y ++ ++N + +P++Y
Sbjct: 234 -----EASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMN--------FRLPLSY 277
Query: 294 ILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQ 353
LV I S + ++K + + F + VF WD+ I N +A K
Sbjct: 278 FLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDYLIGNPETADNKFN 336
Query: 354 ALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFST 413
++ K E I EEK ++ E+ L+ R SG+LI+ A S
Sbjct: 337 SITMNFK-----EAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQ 391
Query: 414 ERLN---ESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYM- 469
E +++G E M + M L ++ E + ++ L ++ IF+ +
Sbjct: 392 EFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLL 451
Query: 470 ----IRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIY---LYISTNGIVCAKHNTDTT 522
+ M + Y ++ G H D
Sbjct: 452 GNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVP 511
Query: 523 KLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKM-FG---EQEF 577
+ CWET VGQ+F +L ++D +VT + + RA R C + +G EF
Sbjct: 512 RGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEF 571
Query: 578 YLPKHVLDIVYVQTIIWMAMF 598
+ +VL +++ Q +IWM F
Sbjct: 572 DISGNVLALIFNQGMIWMGSF 592
>AL590662-1|CAI15164.1| 760|Homo sapiens transmembrane channel-like
1 protein.
Length = 760
Score = 78.2 bits (184), Expect = 8e-14
Identities = 121/561 (21%), Positives = 212/561 (37%), Gaps = 59/561 (10%)
Query: 65 KRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKIE 124
++AR + RR+ R + +I L L L +E+R + I +K P M +KIE
Sbjct: 64 RKAREKERRRR--LKRGAEEEEIDEEELERLKAEL-DEKR--QIIATVKCKPWKMEKKIE 118
Query: 125 LKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLEL-----------WQTPMR 173
+ L+ A K + L + K W F++ + ++K W+ ++
Sbjct: 119 V---LKEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIK 175
Query: 174 EIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTVCC 233
IE +FG+ V SY + IL ++LP+ L
Sbjct: 176 AIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAE-- 233
Query: 234 SIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAY 293
E + N + D G + ++LFYG Y ++ ++N + +P++Y
Sbjct: 234 -----EASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMN--------FRLPLSY 277
Query: 294 ILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQ 353
LV I S + ++K + + F + VF WD+ I N +A K
Sbjct: 278 FLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDYLIGNPETADNKFN 336
Query: 354 ALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFST 413
++ K E I EEK ++ E+ L+ R SG+LI+ A S
Sbjct: 337 SITMNFK-----EAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQ 391
Query: 414 ERLN---ESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYM- 469
E +++G E M + M L ++ E + ++ L ++ IF+ +
Sbjct: 392 EFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLL 451
Query: 470 ----IRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIY---LYISTNGIVCAKHNTDTT 522
+ M + Y ++ G H D
Sbjct: 452 GNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVP 511
Query: 523 KLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKM-FG---EQEF 577
+ CWET VGQ+F +L ++D +VT + + RA R C + +G EF
Sbjct: 512 RGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEF 571
Query: 578 YLPKHVLDIVYVQTIIWMAMF 598
+ +VL +++ Q +IWM F
Sbjct: 572 DISGNVLALIFNQGMIWMGSF 592
>AL162416-1|CAH72129.1| 760|Homo sapiens transmembrane channel-like
1 protein.
Length = 760
Score = 78.2 bits (184), Expect = 8e-14
Identities = 121/561 (21%), Positives = 212/561 (37%), Gaps = 59/561 (10%)
Query: 65 KRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKIE 124
++AR + RR+ R + +I L L L +E+R + I +K P M +KIE
Sbjct: 64 RKAREKERRRR--LKRGAEEEEIDEEELERLKAEL-DEKR--QIIATVKCKPWKMEKKIE 118
Query: 125 LKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLEL-----------WQTPMR 173
+ L+ A K + L + K W F++ + ++K W+ ++
Sbjct: 119 V---LKEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIK 175
Query: 174 EIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTVCC 233
IE +FG+ V SY + IL ++LP+ L
Sbjct: 176 AIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAE-- 233
Query: 234 SIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAY 293
E + N + D G + ++LFYG Y ++ ++N + +P++Y
Sbjct: 234 -----EASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMN--------FRLPLSY 277
Query: 294 ILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQ 353
LV I S + ++K + + F + VF WD+ I N +A K
Sbjct: 278 FLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDYLIGNPETADNKFN 336
Query: 354 ALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFST 413
++ K E I EEK ++ E+ L+ R SG+LI+ A S
Sbjct: 337 SITMNFK-----EAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQ 391
Query: 414 ERLN---ESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYM- 469
E +++G E M + M L ++ E + ++ L ++ IF+ +
Sbjct: 392 EFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLL 451
Query: 470 ----IRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIY---LYISTNGIVCAKHNTDTT 522
+ M + Y ++ G H D
Sbjct: 452 GNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVP 511
Query: 523 KLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKM-FG---EQEF 577
+ CWET VGQ+F +L ++D +VT + + RA R C + +G EF
Sbjct: 512 RGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEF 571
Query: 578 YLPKHVLDIVYVQTIIWMAMF 598
+ +VL +++ Q +IWM F
Sbjct: 572 DISGNVLALIFNQGMIWMGSF 592
>AF417578-1|AAL86399.1| 760|Homo sapiens transmembrane channel-like
protein 1 protein.
Length = 760
Score = 78.2 bits (184), Expect = 8e-14
Identities = 121/561 (21%), Positives = 212/561 (37%), Gaps = 59/561 (10%)
Query: 65 KRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIMQIKALPVPMSQKIE 124
++AR + RR+ R + +I L L L +E+R + I +K P M +KIE
Sbjct: 64 RKAREKERRRR--LKRGAEKEEIDEEELERLKAEL-DEKR--QIIATVKCKPWKMEKKIE 118
Query: 125 LKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLEL-----------WQTPMR 173
+ L+ A K + L + K W F++ + ++K W+ ++
Sbjct: 119 V---LKEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIK 175
Query: 174 EIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTVCC 233
IE +FG+ V SY + IL ++LP+ L
Sbjct: 176 AIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAE-- 233
Query: 234 SIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNMPMAY 293
E + N + D G + ++LFYG Y ++ ++N + +P++Y
Sbjct: 234 -----EASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMN--------FRLPLSY 277
Query: 294 ILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQ 353
LV I S + ++K + + F + VF WD+ I N +A K
Sbjct: 278 FLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDYLIGNPETADNKFN 336
Query: 354 ALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYVAFNFST 413
++ K E I EEK ++ E+ L+ R SG+LI+ A S
Sbjct: 337 SITMNFK-----EAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQ 391
Query: 414 ERLN---ESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPEIFSYM- 469
E +++G E M + M L ++ E + ++ L ++ IF+ +
Sbjct: 392 EFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLL 451
Query: 470 ----IRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIY---LYISTNGIVCAKHNTDTT 522
+ M + Y ++ G H D
Sbjct: 452 GNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVP 511
Query: 523 KLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKM-FG---EQEF 577
+ CWET VGQ+F +L ++D +VT + + RA R C + +G EF
Sbjct: 512 RGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEF 571
Query: 578 YLPKHVLDIVYVQTIIWMAMF 598
+ +VL +++ Q +IWM F
Sbjct: 572 DISGNVLALIFNQGMIWMGSF 592
>BC141860-1|AAI41861.1| 739|Homo sapiens Unknown (protein for
IMAGE:40011719) protein.
Length = 739
Score = 73.3 bits (172), Expect = 2e-12
Identities = 95/447 (21%), Positives = 166/447 (37%), Gaps = 40/447 (8%)
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ ++ IE +FG+ V SY + IL ++LP+ L
Sbjct: 137 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 196
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFY 287
E + N + D G + ++LFYG Y ++ ++N +
Sbjct: 197 PRAE-------EASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMN--------F 238
Query: 288 NMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRS 347
+P++Y LV I S + ++K + + F + VF WD+ I N +
Sbjct: 239 RLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDYLIGNPET 297
Query: 348 ARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYV 407
A K ++ K E I EEK ++ E+ L+ R SG+LI+
Sbjct: 298 ADNKFNSITMNFK-----EAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFW 352
Query: 408 AFNFSTERLN---ESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPE 464
A S E +++G E M + M L ++ E + ++ L ++
Sbjct: 353 AVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGR 412
Query: 465 IFSYM-----IRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIY---LYISTNGIVCAK 516
IF+ + + M + Y ++ G
Sbjct: 413 IFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFV 472
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKM-FG- 573
H D + CWET VGQ+F +L ++D +VT + + RA R C + +G
Sbjct: 473 HPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGY 532
Query: 574 --EQEFYLPKHVLDIVYVQTIIWMAMF 598
EF + +VL +++ Q +IWM F
Sbjct: 533 PSYTEFDISGNVLALIFNQGMIWMGSF 559
>BC114380-1|AAI14381.1| 740|Homo sapiens TMC1 protein protein.
Length = 740
Score = 73.3 bits (172), Expect = 2e-12
Identities = 95/447 (21%), Positives = 166/447 (37%), Gaps = 40/447 (8%)
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ ++ IE +FG+ V SY + IL ++LP+ L
Sbjct: 137 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 196
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFY 287
E + N + D G + ++LFYG Y ++ ++N +
Sbjct: 197 PRAE-------EASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMN--------F 238
Query: 288 NMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRS 347
+P++Y LV I S + ++K + + F + VF WD+ I N +
Sbjct: 239 RLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDYLIGNPET 297
Query: 348 ARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYV 407
A K ++ K E I EEK ++ E+ L+ R SG+LI+
Sbjct: 298 ADNKFNSITMNFK-----EAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFW 352
Query: 408 AFNFSTERLN---ESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPE 464
A S E +++G E M + M L ++ E + ++ L ++
Sbjct: 353 AVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGR 412
Query: 465 IFSYM-----IRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIY---LYISTNGIVCAK 516
IF+ + + M + Y ++ G
Sbjct: 413 IFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFV 472
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKM-FG- 573
H D + CWET VGQ+F +L ++D +VT + + RA R C + +G
Sbjct: 473 HPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGY 532
Query: 574 --EQEFYLPKHVLDIVYVQTIIWMAMF 598
EF + +VL +++ Q +IWM F
Sbjct: 533 PSYTEFDISGNVLALIFNQGMIWMGSF 559
>BC103956-1|AAI03957.1| 727|Homo sapiens TMC1 protein protein.
Length = 727
Score = 73.3 bits (172), Expect = 2e-12
Identities = 95/447 (21%), Positives = 166/447 (37%), Gaps = 40/447 (8%)
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ ++ IE +FG+ V SY + IL ++LP+ L
Sbjct: 137 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 196
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFY 287
E + N + D G + ++LFYG Y ++ ++N +
Sbjct: 197 PRAE-------EASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMN--------F 238
Query: 288 NMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRS 347
+P++Y LV I S + ++K + + F + VF WD+ I N +
Sbjct: 239 RLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDYLIGNPET 297
Query: 348 ARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYV 407
A K ++ K E I EEK ++ E+ L+ R SG+LI+
Sbjct: 298 ADNKFNSITMNFK-----EAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFW 352
Query: 408 AFNFSTERLN---ESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPE 464
A S E +++G E M + M L ++ E + ++ L ++
Sbjct: 353 AVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGR 412
Query: 465 IFSYM-----IRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIY---LYISTNGIVCAK 516
IF+ + + M + Y ++ G
Sbjct: 413 IFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFV 472
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKM-FG- 573
H D + CWET VGQ+F +L ++D +VT + + RA R C + +G
Sbjct: 473 HPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGY 532
Query: 574 --EQEFYLPKHVLDIVYVQTIIWMAMF 598
EF + +VL +++ Q +IWM F
Sbjct: 533 PSYTEFDISGNVLALIFNQGMIWMGSF 559
>AK023655-1|BAB14629.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ13593 fis, clone PLACE1009493. ).
Length = 330
Score = 70.1 bits (164), Expect = 2e-11
Identities = 37/99 (37%), Positives = 58/99 (58%), Gaps = 8/99 (8%)
Query: 503 IYLYISTNGIVCAKHNTDTTKL---ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAF 559
I+L IS GI+C + +T L ECWET +GQ Y+L+L DF V +FL F
Sbjct: 23 IFLKISIIGILCY-YWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFL----GEF 77
Query: 560 MARHTRSRCLKMFGEQEFYLPKHVLDIVYVQTIIWMAMF 598
+ R + + G QEF + ++VL+++Y QT++W+ +F
Sbjct: 78 LRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIF 116
>AL049712-6|CAI22420.2| 906|Homo sapiens transmembrane channel-like
2 protein.
Length = 906
Score = 68.9 bits (161), Expect = 5e-11
Identities = 79/364 (21%), Positives = 150/364 (41%), Gaps = 33/364 (9%)
Query: 51 TLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIM 110
T P ++ ++++ Q R S+ A + + LS +L++ L E + I
Sbjct: 111 TAAPKREKEIPRREEKSKRQKKPRSSSLASSASGGE-SLSE-EELAQILEQVEEKKKLIA 168
Query: 111 QIKALPVPMSQKI-ELKARLQNATK----LRLQGFEQLH---LRQRKVWHRFRIGCTETF 162
+++ P PM++K+ EL+ + K L +QL+ + K W +F+
Sbjct: 169 TMRSKPWPMAKKLTELREAQEFVEKYEGALGKGKGKQLYAYKMLMAKKWVKFKRDFDNFK 228
Query: 163 SKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYEC 222
++ W+ +++IE FG+ V SY + L+ +I+P+ L+
Sbjct: 229 TQCIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSI 288
Query: 223 DETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYH 282
E+ + ++ D G+++ + LFYG Y +Q ++
Sbjct: 289 PRKTVPRAE-------EEKAMDFSVLWDF---EGYIKYSALFYGYYNNQRTIGWLR---- 334
Query: 283 TKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCI 342
Y +PMAY +V +S SLI ++++ A + E E + + +F WD+ I
Sbjct: 335 ----YRLPMAYFMVGVSVFGYSLIIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLI 390
Query: 343 HNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASG 402
N +A K+ ++ K E I +E++S E+ L R SG
Sbjct: 391 GNSETADNKYASITTSFK-----ESIVDEQESNKEENIHLTRFLRVLANFLIICCLCGSG 445
Query: 403 FLIY 406
+LIY
Sbjct: 446 YLIY 449
Score = 45.6 bits (103), Expect = 5e-04
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKMF--- 572
H D + CWET VG +F +L ++D V ++T L + RA R C +
Sbjct: 565 HPADVPRGSCWETAVGIEFMRLTVSDMLVTYITILLGDFLRACFVRFMNYCWCWDLEAGF 624
Query: 573 -GEQEFYLPKHVLDIVYVQTIIWMAMF 598
EF + +VL +++ Q +IWM F
Sbjct: 625 PSYAEFDISGNVLGLIFNQGMIWMGSF 651
>AF417580-1|AAL86401.2| 906|Homo sapiens transmembrane channel-like
protein 2 protein.
Length = 906
Score = 68.9 bits (161), Expect = 5e-11
Identities = 79/364 (21%), Positives = 150/364 (41%), Gaps = 33/364 (9%)
Query: 51 TLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIM 110
T P ++ ++++ Q R S+ A + + LS +L++ L E + I
Sbjct: 111 TAAPKREKEIPRKEEKSKRQKKPRSSSLASSASGGE-SLSE-EELAQILEQVEEKKKLIA 168
Query: 111 QIKALPVPMSQKI-ELKARLQNATK----LRLQGFEQLH---LRQRKVWHRFRIGCTETF 162
+++ P PM++K+ EL+ + K L +QL+ + K W +F+
Sbjct: 169 TMRSKPWPMAKKLTELREAQEFVEKYEGALGKGKGKQLYAYKMLMAKKWVKFKRDFDNFK 228
Query: 163 SKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYEC 222
++ W+ +++IE FG+ V SY + L+ +I+P+ L+
Sbjct: 229 TQCIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSI 288
Query: 223 DETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYH 282
E+ + ++ D G+++ + LFYG Y +Q ++
Sbjct: 289 PRKTVPRAE-------EEKAMDFSVLWDF---EGYIKYSALFYGYYNNQRTIGWLR---- 334
Query: 283 TKLFYNMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCI 342
Y +PMAY +V +S SLI ++++ A + E E + + +F WD+ I
Sbjct: 335 ----YRLPMAYFMVGVSVFGYSLIIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLI 390
Query: 343 HNDRSARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASG 402
N +A K+ ++ K E I +E++S E+ L R SG
Sbjct: 391 GNSETADNKYASITTSFK-----ESIVDEQESNKEENIHLTRFLRVLANFLIICCLCGSG 445
Query: 403 FLIY 406
+LIY
Sbjct: 446 YLIY 449
Score = 45.6 bits (103), Expect = 5e-04
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTR-SRCLKMF--- 572
H D + CWET VG +F +L ++D V ++T L + RA R C +
Sbjct: 565 HPADVPRGSCWETAVGIEFMRLTVSDMLVTYITILLGDFLRACFVRFMNYCWCWDLEAGF 624
Query: 573 -GEQEFYLPKHVLDIVYVQTIIWMAMF 598
EF + +VL +++ Q +IWM F
Sbjct: 625 PSYAEFDISGNVLGLIFNQGMIWMGSF 651
>BC032477-1|AAH32477.1| 294|Homo sapiens TMC4 protein protein.
Length = 294
Score = 67.7 bits (158), Expect = 1e-10
Identities = 28/76 (36%), Positives = 41/76 (53%)
Query: 523 KLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKH 582
+L CWET +GQ+ YKL+L D LI PR + ++ G QEF +P
Sbjct: 54 QLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDE 113
Query: 583 VLDIVYVQTIIWMAMF 598
VL ++Y QT++W+ F
Sbjct: 114 VLGLIYAQTVVWVGSF 129
>BC103955-1|AAI03956.1| 554|Homo sapiens TMC1 protein protein.
Length = 554
Score = 65.7 bits (153), Expect = 5e-10
Identities = 84/406 (20%), Positives = 147/406 (36%), Gaps = 35/406 (8%)
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ ++ IE +FG+ V SY + IL ++LP+ L
Sbjct: 137 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 196
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFY 287
E + N + D G + ++LFYG Y ++ ++N +
Sbjct: 197 PRAE-------EASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMN--------F 238
Query: 288 NMPMAYILVPISWTLLSLIAIVKTAARGFKQKLIESEGQFYKYCNLVFGGWDFCIHNDRS 347
+P++Y LV I S + ++K + + F + VF WD+ I N +
Sbjct: 239 RLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDYLIGNPET 297
Query: 348 ARIKHQALYNEIKGCIEEERIKEEKQSRSRESQILMHLKRXXXXXXXXXXXXASGFLIYV 407
A K ++ K E I EEK ++ E+ L+ R SG+LI+
Sbjct: 298 ADNKFNSITMNFK-----EAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFW 352
Query: 408 AFNFSTERLN---ESIGSNENRTRTMPIVYTTMSFNQLENVLMEFLPFICIVVLNLIIPE 464
A S E +++G E M + M L ++ E + ++ L ++
Sbjct: 353 AVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGR 412
Query: 465 IFSYM-----IRYEGYMPPHXXXXXXXXXXXXXXXXXXXXXXQIY---LYISTNGIVCAK 516
IF+ + + M + Y ++ G
Sbjct: 413 IFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFV 472
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMAR 562
H D + CWET VGQ+F +L ++D +VT + + RA R
Sbjct: 473 HPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVR 518
>BC035648-1|AAH35648.1| 444|Homo sapiens TMC6 protein protein.
Length = 444
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ DF + + T L + R + LK + EF + ++VL
Sbjct: 178 QCWEDFVGQELYRFLVMDFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 233
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 234 ELIYGQTLTWLGV 246
>BC023597-1|AAH23597.1| 805|Homo sapiens transmembrane channel-like
6 protein.
Length = 805
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ DF + + T L + R + LK + EF + ++VL
Sbjct: 539 QCWEDFVGQELYRFLVMDFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 594
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 595 ELIYGQTLTWLGV 607
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/244 (20%), Positives = 100/244 (40%), Gaps = 36/244 (14%)
Query: 152 HRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILP 211
H + L W+ ++ I G+FG+ V+SY + +L++ F++ P
Sbjct: 214 HSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGP 273
Query: 212 KTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQ 271
+ + + VC L+++ G G T+++YG Y++
Sbjct: 274 QVAFPPAL------PGPAPVCTG--------------LELLTGAGCFTHTVMYYGHYSNA 313
Query: 272 IYTYYVNSLYHTK--------LFYNMPMAYI-LVPISWTLLSLIAIVKTAARGFKQKL-I 321
S L YNMP+AY+ V +S+ ++ I +V + A F + +
Sbjct: 314 TLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSF-FITCITLVYSMAHSFGESYRV 372
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQS---RSRE 378
S + VF WD+ + R++R++ + +K + E +++ +S R R+
Sbjct: 373 GSTSGIHAI--TVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQ 430
Query: 379 SQIL 382
+ +L
Sbjct: 431 AAVL 434
>BC018346-1|AAH18346.2| 513|Homo sapiens TMC6 protein protein.
Length = 513
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ DF + + T L + R + LK + EF + ++VL
Sbjct: 247 QCWEDFVGQELYRFLVMDFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 302
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 303 ELIYGQTLTWLGV 315
Score = 38.3 bits (85), Expect = 0.079
Identities = 33/145 (22%), Positives = 67/145 (46%), Gaps = 16/145 (11%)
Query: 251 VIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTK--------LFYNMPMAYI-LVPISWT 301
++ G G T+++YG Y++ S L YNMP+AY+ V +S+
Sbjct: 1 LLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSF- 59
Query: 302 LLSLIAIVKTAARGFKQKL-IESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIK 360
++ I +V + A F + + S + VF WD+ + R++R++ + +K
Sbjct: 60 FITCITLVYSMAHSFGESYRVGSTSGIHAI--TVFCSWDYKVTQKRASRLQQDNIRTRLK 117
Query: 361 GCIEEERIKEEKQS---RSRESQIL 382
+ E +++ +S R R++ +L
Sbjct: 118 ELLAEWQLRHSPRSVCGRLRQAAVL 142
>AY099356-1|AAM44452.1| 805|Homo sapiens large EVER1 protein
protein.
Length = 805
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ DF + + T L + R + LK + EF + ++VL
Sbjct: 539 QCWEDFVGQELYRFLVMDFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 594
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 595 ELIYGQTLTWLGV 607
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/244 (20%), Positives = 100/244 (40%), Gaps = 36/244 (14%)
Query: 152 HRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILP 211
H + L W+ ++ I G+FG+ V+SY + +L++ F++ P
Sbjct: 214 HSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGP 273
Query: 212 KTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQ 271
+ + + VC L+++ G G T+++YG Y++
Sbjct: 274 QVAFPPAL------PGPAPVCTG--------------LELLTGAGCFTHTVMYYGHYSNA 313
Query: 272 IYTYYVNSLYHTK--------LFYNMPMAYI-LVPISWTLLSLIAIVKTAARGFKQKL-I 321
S L YNMP+AY+ V +S+ ++ I +V + A F + +
Sbjct: 314 TLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSF-FITCITLVYSMAHSFGESYRV 372
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQS---RSRE 378
S + VF WD+ + R++R++ + +K + E +++ +S R R+
Sbjct: 373 GSTSGIHAI--TVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQ 430
Query: 379 SQIL 382
+ +L
Sbjct: 431 AAVL 434
>AY057379-1|AAL25836.1| 805|Homo sapiens EVIN1 protein.
Length = 805
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ DF + + T L + R + LK + EF + ++VL
Sbjct: 539 QCWEDFVGQELYRFLVMDFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 594
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 595 ELIYGQTLTWLGV 607
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/244 (20%), Positives = 100/244 (40%), Gaps = 36/244 (14%)
Query: 152 HRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILP 211
H + L W+ ++ I G+FG+ V+SY + +L++ F++ P
Sbjct: 214 HSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGP 273
Query: 212 KTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQ 271
+ + + VC L+++ G G T+++YG Y++
Sbjct: 274 QVAFPPAL------PGPAPVCTG--------------LELLTGAGCFTHTVMYYGHYSNA 313
Query: 272 IYTYYVNSLYHTK--------LFYNMPMAYI-LVPISWTLLSLIAIVKTAARGFKQKL-I 321
S L YNMP+AY+ V +S+ ++ I +V + A F + +
Sbjct: 314 TLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSF-FITCITLVYSMAHSFGESYRV 372
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQS---RSRE 378
S + VF WD+ + R++R++ + +K + E +++ +S R R+
Sbjct: 373 GSTSGIHAI--TVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQ 430
Query: 379 SQIL 382
+ +L
Sbjct: 431 AAVL 434
>AK074065-1|BAB84891.1| 811|Homo sapiens FLJ00136 protein protein.
Length = 811
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ DF + + T L + R + LK + EF + ++VL
Sbjct: 545 QCWEDFVGQELYRFLVMDFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 600
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 601 ELIYGQTLTWLGV 613
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/244 (20%), Positives = 100/244 (40%), Gaps = 36/244 (14%)
Query: 152 HRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILP 211
H + L W+ ++ I G+FG+ V+SY + +L++ F++ P
Sbjct: 220 HSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGP 279
Query: 212 KTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQ 271
+ + + VC L+++ G G T+++YG Y++
Sbjct: 280 QVAFPPAL------PGPAPVCTG--------------LELLTGAGCFTHTVMYYGHYSNA 319
Query: 272 IYTYYVNSLYHTK--------LFYNMPMAYI-LVPISWTLLSLIAIVKTAARGFKQKL-I 321
S L YNMP+AY+ V +S+ ++ I +V + A F + +
Sbjct: 320 TLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSF-FITCITLVYSMAHSFGESYRV 378
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQS---RSRE 378
S + VF WD+ + R++R++ + +K + E +++ +S R R+
Sbjct: 379 GSTSGIHAI--TVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQ 436
Query: 379 SQIL 382
+ +L
Sbjct: 437 AAVL 440
>AB002405-1|BAA24179.2| 444|Homo sapiens LAK-4p protein.
Length = 444
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ DF + + T L + R + LK + EF + ++VL
Sbjct: 178 QCWEDFVGQELYRFLVMDFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 233
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 234 ELIYGQTLTWLGV 246
>AY236496-1|AAP69874.1| 805|Homo sapiens transmembrane channel-like
protein 6 protein.
Length = 805
Score = 47.2 bits (107), Expect = 2e-04
Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMARHTRSRCLKMFGEQEFYLPKHVL 584
+CWE +VGQ+ Y+ ++ F + + T L + R + LK + EF + ++VL
Sbjct: 539 QCWEDFVGQELYRFLVMGFVLMLLDTLFGEL----VWRIISEKKLKRRRKPEFDIARNVL 594
Query: 585 DIVYVQTIIWMAM 597
+++Y QT+ W+ +
Sbjct: 595 ELIYGQTLTWLGV 607
Score = 45.6 bits (103), Expect = 5e-04
Identities = 49/244 (20%), Positives = 99/244 (40%), Gaps = 36/244 (14%)
Query: 152 HRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILP 211
H + L W+ ++ I G+FG+ V+SY + +L + F++ P
Sbjct: 214 HSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLPVAFIMGP 273
Query: 212 KTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQ 271
+ + + VC L+++ G G T+++YG Y++
Sbjct: 274 QVAFPPAL------PGPAPVCTG--------------LELLTGAGCFTHTVMYYGHYSNA 313
Query: 272 IYTYYVNSLYHTK--------LFYNMPMAYI-LVPISWTLLSLIAIVKTAARGFKQKL-I 321
S L YNMP+AY+ V +S+ ++ I +V + A F + +
Sbjct: 314 TLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSF-FITCITLVYSMAHSFGESYRV 372
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQS---RSRE 378
S + VF WD+ + R++R++ + +K + E +++ +S R R+
Sbjct: 373 GSTSGIHAI--TVFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQ 430
Query: 379 SQIL 382
+ +L
Sbjct: 431 AAVL 434
>AK021738-1|BAB13884.1| 298|Homo sapiens protein ( Homo sapiens
cDNA FLJ11676 fis, clone HEMBA1004752, highly similar to
Homo sapiens mRNA for LAK-4p. ).
Length = 298
Score = 45.6 bits (103), Expect = 5e-04
Identities = 47/228 (20%), Positives = 97/228 (42%), Gaps = 36/228 (15%)
Query: 168 WQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEA 227
W+ ++ I G+FG+ V+SY + +L++ F++ P+ +
Sbjct: 3 WRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPAL------PG 56
Query: 228 NSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTK--- 284
+ VC L+++ G G T+++YG Y++ S
Sbjct: 57 PAPVCTG--------------LELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQCT 102
Query: 285 -----LFYNMPMAYI-LVPISWTLLSLIAIVKTAARGFKQKL-IESEGQFYKYCNLVFGG 337
L YNMP+AY+ V +S+ ++ I +V + A F + + S + VF
Sbjct: 103 PRVGGLPYNMPLAYLSTVGVSF-FITCITLVYSMAHSFGESYRVGSTSGIHAI--TVFCS 159
Query: 338 WDFCIHNDRSARIKHQALYNEIKGCIEEERIKEEKQS---RSRESQIL 382
WD+ + R++R++ + +K + E +++ +S R R++ +L
Sbjct: 160 WDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVL 207
>AY099357-1|AAM44453.1| 454|Homo sapiens small EVER1 protein
protein.
Length = 454
Score = 44.8 bits (101), Expect = 0.001
Identities = 45/220 (20%), Positives = 88/220 (40%), Gaps = 33/220 (15%)
Query: 152 HRFRIGCTETFSKLELWQTPMREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILP 211
H + L W+ ++ I G+FG+ V+SY + +L++ F++ P
Sbjct: 214 HSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGP 273
Query: 212 KTLLTERVYECDETEANSTVCCSIAYFEKNTTNSNIFLDVIQGTGWMERTILFYGVYTDQ 271
+ + + VC L+++ G G T+++YG Y++
Sbjct: 274 QVAFPPAL------PGPAPVCTG--------------LELLTGAGCFTHTVMYYGHYSNA 313
Query: 272 IYTYYVNSLYHTK--------LFYNMPMAYI-LVPISWTLLSLIAIVKTAARGFKQKL-I 321
S L YNMP+AY+ V +S+ ++ I +V + A F + +
Sbjct: 314 TLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVSF-FITCITLVYSMAHSFGESYRV 372
Query: 322 ESEGQFYKYCNLVFGGWDFCIHNDRSARIKHQALYNEIKG 361
S + VF WD+ + R++R++ + +KG
Sbjct: 373 GSTSGIHAIT--VFCSWDYKVTQKRASRLQQDNIRTRLKG 410
>BC028076-1|AAH28076.1| 287|Homo sapiens TMC8 protein protein.
Length = 287
Score = 41.1 bits (92), Expect = 0.011
Identities = 49/198 (24%), Positives = 81/198 (40%), Gaps = 9/198 (4%)
Query: 112 IKALPVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKVWHRFRIGCTETFSKLELWQTP 171
++ LP M K L +L+ ++ +++ R++ V R R L LW+
Sbjct: 36 VRGLPYAMMDK-RLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA 94
Query: 172 MREIEGKFGTGVVSYXXXXXXXXXXXXTISILVIVFLILPKTLLTERVYECDETEANSTV 231
+ EI G FGTG+ SY +L F++LP L+ R + T +
Sbjct: 95 LYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP--LVWLRPPDPGPTLNLTLQ 152
Query: 232 CCSIAYFEKNTTN-SNIFLDVIQGTGWMERTILFYGVYTDQIYTYYVNSLYHTKLFYNM- 289
C N V+ G + T LFYG Y + +S+Y +L Y +
Sbjct: 153 CPGSRQSPPGVLRFHNQLWHVLTGRAF-TNTYLFYGAYRVGPES---SSVYSIRLAYLLS 208
Query: 290 PMAYILVPISWTLLSLIA 307
P+A +L+ TL L++
Sbjct: 209 PLACLLLCFCGTLHQLLS 226
>AK094789-1|BAC04423.1| 205|Homo sapiens protein ( Homo sapiens
cDNA FLJ37470 fis, clone BRAWH2012258. ).
Length = 205
Score = 38.7 bits (86), Expect = 0.059
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 517 HNTDTTKLECWETYVGQQFYKLILTDFAVQFVTTFLINLPRAFMAR 562
H D + CWET VG +F +L ++D V ++T L + RA R
Sbjct: 105 HPADVPRGSCWETAVGIEFMRLTVSDMLVTYITILLGDFLRACFVR 150
>BC007766-1|AAH07766.1| 211|Homo sapiens TMC6 protein protein.
Length = 211
Score = 34.3 bits (75), Expect = 1.3
Identities = 10/26 (38%), Positives = 18/26 (69%)
Query: 525 ECWETYVGQQFYKLILTDFAVQFVTT 550
+CWE +VGQ+ Y+ ++ DF + + T
Sbjct: 178 QCWEDFVGQELYRFLVMDFVLMLLDT 203
>X90824-1|CAA62339.1| 292|Homo sapiens USF2a, USF2b protein
protein.
Length = 292
Score = 32.7 bits (71), Expect = 3.9
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 3/125 (2%)
Query: 20 EAGGEFYQELYPGGEQELFDNLQRADAAKLATLLPSKQARNTTTVKRARSQTDRRQSTFA 79
+AGG+FY + P + L QR A + P T +R R+Q + +
Sbjct: 145 QAGGQFYVMMTP--QDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRR 202
Query: 80 RTMQSRDIHLS-MLPDLSENLSNEERSWEEIMQIKALPVPMSQKIELKARLQNATKLRLQ 138
+ + + LS ++PD + + S + + I +++ M + + RLQ +L Q
Sbjct: 203 DKINNWIVQLSKIIPDCNADNSKTGAACDYIRELRQTNQRMQETFKEAERLQMDNELLRQ 262
Query: 139 GFEQL 143
E+L
Sbjct: 263 QIEEL 267
>BC069194-1|AAH69194.1| 1118|Homo sapiens PHLDB2 protein protein.
Length = 1118
Score = 32.3 bits (70), Expect = 5.2
Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 50 ATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEI 109
A+ + RN + STF + S +LS+LP E +S E+RS E
Sbjct: 530 ASFFTPRSTRNDELLSDLTRTPPPPSSTFPKA-SSESSYLSILPKTPEGISEEQRSQELA 588
Query: 110 MQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHL 145
+ V ++ ELK ++++ + F +L +
Sbjct: 589 AMEETRIVILNNLEELKQKIKDINDQMDESFRELDM 624
>AL359963-2|CAH71092.1| 900|Homo sapiens erythrocyte membrane
protein band 4.1 like 4B protein.
Length = 900
Score = 32.3 bits (70), Expect = 5.2
Identities = 15/45 (33%), Positives = 30/45 (66%), Gaps = 3/45 (6%)
Query: 98 NLSNEERSWEEIMQIKALPVPMSQKIE---LKARLQNATKLRLQG 139
N + E++ E+ +Q LP P++ ++ LKA+L+NA+++ +QG
Sbjct: 583 NKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQG 627
>AL358815-2|CAI15129.1| 900|Homo sapiens erythrocyte membrane
protein band 4.1 like 4B protein.
Length = 900
Score = 32.3 bits (70), Expect = 5.2
Identities = 15/45 (33%), Positives = 30/45 (66%), Gaps = 3/45 (6%)
Query: 98 NLSNEERSWEEIMQIKALPVPMSQKIE---LKARLQNATKLRLQG 139
N + E++ E+ +Q LP P++ ++ LKA+L+NA+++ +QG
Sbjct: 583 NKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQG 627
>AK125555-1|BAC86200.1| 373|Homo sapiens protein ( Homo sapiens
cDNA FLJ43567 fis, clone PUAEN2007785. ).
Length = 373
Score = 32.3 bits (70), Expect = 5.2
Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 50 ATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEI 109
A+ + RN + STF + S +LS+LP E +S E+RS E
Sbjct: 116 ASFFTPRSTRNDELLSDLTRTPPPPSSTFPKA-SSESSYLSILPKTPEGISEEQRSQELA 174
Query: 110 MQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHL 145
+ V ++ ELK ++++ + F +L +
Sbjct: 175 AMEETRIVILNNLEELKQKIKDINDQMDESFRELDM 210
>AK096151-1|BAC04713.1| 745|Homo sapiens protein ( Homo sapiens
cDNA FLJ38832 fis, clone MESAN2000457. ).
Length = 745
Score = 32.3 bits (70), Expect = 5.2
Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 50 ATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEI 109
A+ + RN + STF + S +LS+LP E +S E+RS E
Sbjct: 530 ASFFTPRSTRNDELLSDLTRTPPPPSSTFPKA-SSESSYLSILPKTPEGISEEQRSQELA 588
Query: 110 MQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHL 145
+ V ++ ELK ++++ + F +L +
Sbjct: 589 AMEETRIVILNNLEELKQKIKDINDQMDESFRELDM 624
>AK092996-1|BAC04014.1| 787|Homo sapiens protein ( Homo sapiens
cDNA FLJ35677 fis, clone SPLEN2018749. ).
Length = 787
Score = 32.3 bits (70), Expect = 5.2
Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 50 ATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEI 109
A+ + RN + STF + S +LS+LP E +S E+RS E
Sbjct: 530 ASFFTPRSTRNDELLSDLTRTPPPPSSTFPKA-SSESSYLSILPKTPEGISEEQRSQELA 588
Query: 110 MQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHL 145
+ V ++ ELK ++++ + F +L +
Sbjct: 589 AMEETRIVILNNLEELKQKIKDINDQMDESFRELDM 624
>AF506820-1|AAM33634.1| 1210|Homo sapiens hypothetical protein
protein.
Length = 1210
Score = 32.3 bits (70), Expect = 5.2
Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 50 ATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEI 109
A+ + RN + STF + S +LS+LP E +S E+RS E
Sbjct: 530 ASFFTPRSTRNDELLSDLTRTPPPPSSTFPKA-SSESSYLSILPKTPEGISEEQRSQELA 588
Query: 110 MQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHL 145
+ V ++ ELK ++++ + F +L +
Sbjct: 589 AMEETRIVILNNLEELKQKIKDINDQMDESFRELDM 624
>AF153416-1|AAG43366.1| 913|Homo sapiens FERM-containing protein
protein.
Length = 913
Score = 32.3 bits (70), Expect = 5.2
Identities = 15/45 (33%), Positives = 30/45 (66%), Gaps = 3/45 (6%)
Query: 98 NLSNEERSWEEIMQIKALPVPMSQKIE---LKARLQNATKLRLQG 139
N + E++ E+ +Q LP P++ ++ LKA+L+NA+++ +QG
Sbjct: 569 NKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQG 613
>AB209903-1|BAD93140.1| 1259|Homo sapiens LL5 beta protein variant
protein.
Length = 1259
Score = 32.3 bits (70), Expect = 5.2
Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 50 ATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEI 109
A+ + RN + STF + S +LS+LP E +S E+RS E
Sbjct: 536 ASFFTPRSTRNDELLSDLTRTPPPPSSTFPKA-SSESSYLSILPKTPEGISEEQRSQELA 594
Query: 110 MQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHL 145
+ V ++ ELK ++++ + F +L +
Sbjct: 595 AMEETRIVILNNLEELKQKIKDINDQMDESFRELDM 630
>AB209187-1|BAD92424.1| 603|Homo sapiens erythrocyte membrane
protein band 4.1 like 4B variant protein.
Length = 603
Score = 32.3 bits (70), Expect = 5.2
Identities = 15/45 (33%), Positives = 30/45 (66%), Gaps = 3/45 (6%)
Query: 98 NLSNEERSWEEIMQIKALPVPMSQKIE---LKARLQNATKLRLQG 139
N + E++ E+ +Q LP P++ ++ LKA+L+NA+++ +QG
Sbjct: 286 NKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQG 330
>AJ496194-1|CAD42711.1| 1253|Homo sapiens LL5 beta protein protein.
Length = 1253
Score = 31.9 bits (69), Expect = 6.8
Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 50 ATLLPSKQARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEI 109
A+ + RN + STF + S +LS+LP E +S E+RS E
Sbjct: 530 ASFFTPRSTRNDELLSDLTRTPPPPSSTFPKA-SSESSYLSILPKTPEGISEEQRSEELA 588
Query: 110 MQIKALPVPMSQKIELKARLQNATKLRLQGFEQLHL 145
+ V ++ ELK ++++ + F +L +
Sbjct: 589 AMEETRIVILNNLEELKQKIKDINDQMDESFRELDM 624
>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
Golgi-localized PKN-associated protein (CG-NAP) protein.
Length = 3899
Score = 31.9 bits (69), Expect = 6.8
Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Query: 57 QARNTTTVKRARSQTDRRQSTFARTMQSRDIHLSMLPDLSENLSNEERSWEEIMQ-IKAL 115
Q N TTVK S D ++ A T++ ++ +L ENL +R E+ Q + L
Sbjct: 903 QRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMENLEVTKREKLELSQRLSDL 962
Query: 116 PVPMSQKIELKARLQNATKLRLQGFEQLHLRQRKV 150
+ QK + L K Q EQ+ LR R++
Sbjct: 963 SEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCREL 997
>AM183303-1|CAJ66088.1| 418|Homo sapiens autogenous vein graft
remodeling associated protein 2 protein.
Length = 418
Score = 31.5 bits (68), Expect = 9.0
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 53 LPSKQARNTTTVKRARSQTDRRQSTFARTMQS-RDIHLSMLPDLSENLSNEERSWEEIMQ 111
+P + T +++R+ S A S D+ L LPD+ + NEE W ++
Sbjct: 85 IPQHHSTEFTEGNPTGQRSERKTSNKAHKGASPADLMLQDLPDIGQQQDNEESWWNPVLM 144
Query: 112 IKALPVPMSQ 121
++ P +Q
Sbjct: 145 VEQKPEASNQ 154
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.324 0.137 0.414
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,110,889
Number of Sequences: 224733
Number of extensions: 2999637
Number of successful extensions: 10498
Number of sequences better than 10.0: 62
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 10291
Number of HSP's gapped (non-prelim): 144
length of query: 612
length of database: 73,234,838
effective HSP length: 94
effective length of query: 518
effective length of database: 52,109,936
effective search space: 26992946848
effective search space used: 26992946848
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 68 (31.5 bits)
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