Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000065-TA|BGIBMGA000065-PA|IPR001216|Cysteine
synthase/cystathionine beta-synthase P-phosphate-binding site,
IPR001926|Pyridoxal-5'-phosphate-dependent enzyme, beta subunit
(440 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VRD9 Cluster: CG1753-PA, isoform A; n=8; Pancrustacea... 337 4e-91
UniRef50_P35520 Cluster: Cystathionine beta-synthase; n=57; cell... 319 1e-85
UniRef50_Q9YHU3 Cluster: Cystathionine beta-synthetase; n=14; Eu... 312 9e-84
UniRef50_P46794 Cluster: Cystathionine beta-synthase; n=5; Eukar... 299 1e-79
UniRef50_A0DFI6 Cluster: Chromosome undetermined scaffold_49, wh... 295 1e-78
UniRef50_Q4QEG9 Cluster: Cysteine synthase; n=18; Trypanosomatid... 290 4e-77
UniRef50_Q23264 Cluster: Putative uncharacterized protein; n=2; ... 282 1e-74
UniRef50_A7S1D2 Cluster: Predicted protein; n=1; Nematostella ve... 270 6e-71
UniRef50_A2QKG7 Cluster: Contig An05c0010, complete genome; n=21... 260 5e-68
UniRef50_Q1DVL4 Cluster: Cysteine synthase; n=3; Fungi/Metazoa g... 246 1e-63
UniRef50_P32582 Cluster: Cystathionine beta-synthase; n=10; Sacc... 245 2e-63
UniRef50_Q6MGX3 Cluster: Cysteine synthase; n=2; Bacteria|Rep: C... 239 8e-62
UniRef50_A7HH29 Cluster: Pyridoxal-5'-phosphate-dependent protei... 230 5e-59
UniRef50_Q129P7 Cluster: Cysteine synthase; n=22; cellular organ... 219 1e-55
UniRef50_Q1INP9 Cluster: Cysteine synthases; n=1; Acidobacteria ... 217 5e-55
UniRef50_A5N6W4 Cluster: Cysteine synthase; n=1; Clostridium klu... 216 1e-54
UniRef50_Q9CB65 Cluster: Cystathionine; n=13; Actinomycetales|Re... 212 2e-53
UniRef50_Q7D8W0 Cluster: Cysteine synthase/cystathionine beta-sy... 211 2e-53
UniRef50_Q8G564 Cluster: Cystathionine beta-synthase; n=2; Bifid... 206 7e-52
UniRef50_Q3B030 Cluster: Cysteine synthase; n=22; Bacteria|Rep: ... 201 3e-50
UniRef50_A1ZUX3 Cluster: Cysteine synthase; n=1; Microscilla mar... 198 2e-49
UniRef50_A7HGE3 Cluster: Cysteine synthase precursor; n=9; Bacte... 197 4e-49
UniRef50_A7GZ74 Cluster: Cysteine synthase A; n=1; Campylobacter... 194 3e-48
UniRef50_A6GXZ8 Cluster: Cysteine synthase/cystathionine beta-sy... 194 5e-48
UniRef50_Q4S0J1 Cluster: Chromosome 2 SCAF14781, whole genome sh... 193 7e-48
UniRef50_Q1W0E5 Cluster: Cystathionine beta-synthase; n=12; Bact... 193 7e-48
UniRef50_Q15UN6 Cluster: Cysteine synthase; n=1; Pseudoalteromon... 193 7e-48
UniRef50_Q7MYV0 Cluster: Cysteine synthase; n=1; Photorhabdus lu... 190 8e-47
UniRef50_A3DLF6 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 188 3e-46
UniRef50_Q0AX09 Cluster: Cysteine synthase; n=5; Clostridiales|R... 185 2e-45
UniRef50_Q130S8 Cluster: Cysteine synthase; n=2; Proteobacteria|... 184 3e-45
UniRef50_Q0SJ57 Cluster: Cysteine synthase; n=2; Bacteria|Rep: C... 182 2e-44
UniRef50_UPI0001597832 Cluster: YtkP; n=1; Bacillus amyloliquefa... 181 4e-44
UniRef50_Q3A4C8 Cluster: Cysteine synthase; n=2; Deltaproteobact... 177 5e-43
UniRef50_O15570 Cluster: Cysteine synthase; n=8; Entamoeba|Rep: ... 177 5e-43
UniRef50_A0K1R0 Cluster: Cysteine synthase; n=3; Micrococcineae|... 175 1e-42
UniRef50_Q74FS1 Cluster: Cysteine synthase A; n=25; Bacteria|Rep... 175 2e-42
UniRef50_O32978 Cluster: Cysteine synthase A (EC 2.5.1.47) (O-ac... 175 2e-42
UniRef50_Q98DX5 Cluster: Cysteine synthase; n=42; Bacteria|Rep: ... 174 3e-42
UniRef50_Q6ANV5 Cluster: Cysteine synthase; n=2; Bacteria|Rep: C... 174 3e-42
UniRef50_Q0AWJ8 Cluster: O-acetylserine (Thiol)-lyase; n=1; Synt... 173 6e-42
UniRef50_UPI00015BB1D1 Cluster: Pyridoxal-5'-phosphate-dependent... 172 2e-41
UniRef50_Q9REQ7 Cluster: Cysteine synthase; n=6; Proteobacteria|... 171 2e-41
UniRef50_A6SDF3 Cluster: Cysteine synthase; n=1; Botryotinia fuc... 171 3e-41
UniRef50_Q43725 Cluster: Cysteine synthase, mitochondrial precur... 170 5e-41
UniRef50_P71128 Cluster: Cysteine synthase B (EC 2.5.1.47) (O-ac... 170 7e-41
UniRef50_A6GJR2 Cluster: Cysteine synthase; n=1; Plesiocystis pa... 168 3e-40
UniRef50_Q9XEA7 Cluster: Cysteine synthase; n=10; Oryza sativa|R... 167 4e-40
UniRef50_Q54CN7 Cluster: Cysteine synthase; n=1; Dictyostelium d... 167 4e-40
UniRef50_O59701 Cluster: Cysteine synthase 1 (EC 2.5.1.47) (O-ac... 167 5e-40
UniRef50_Q59447 Cluster: Cysteine synthase (EC 2.5.1.47) (O-acet... 166 9e-40
UniRef50_A0LFH6 Cluster: Cysteine synthase; n=6; cellular organi... 166 1e-39
UniRef50_Q8L0X3 Cluster: L-cysteine desulfhydrase; n=4; Fusobact... 165 2e-39
UniRef50_P56067 Cluster: Cysteine synthase (EC 2.5.1.47) (O-acet... 165 2e-39
UniRef50_Q6MM94 Cluster: Cysteine synthase; n=3; Deltaproteobact... 165 3e-39
UniRef50_Q4PAS1 Cluster: Cysteine synthase; n=1; Ustilago maydis... 165 3e-39
UniRef50_P38076 Cluster: Cysteine synthase (EC 2.5.1.47) (O-acet... 163 6e-39
UniRef50_Q9RW80 Cluster: Cysteine synthase; n=13; Bacteria|Rep: ... 161 4e-38
UniRef50_A5IQ12 Cluster: Cysteine synthase; n=16; Staphylococcus... 160 6e-38
UniRef50_Q7VHW4 Cluster: Cysteine synthase; n=2; Campylobacteral... 159 1e-37
UniRef50_Q4AMJ6 Cluster: Cysteine synthase K/M:Cysteine synthase... 159 2e-37
UniRef50_Q7VK29 Cluster: Cysteine synthase; n=13; Bacteria|Rep: ... 155 2e-36
UniRef50_Q1GGP4 Cluster: Cysteine synthase; n=110; cellular orga... 155 2e-36
UniRef50_Q9HQ70 Cluster: Cysteine synthase; n=5; Halobacteriacea... 154 4e-36
UniRef50_Q4JSP4 Cluster: Cystathionine beta-synthase; n=3; Actin... 153 9e-36
UniRef50_UPI00006CB05C Cluster: Pyridoxal-phosphate dependent en... 153 1e-35
UniRef50_Q4LEC7 Cluster: O-acetyl-L-serine sulfhydrylase; n=1; u... 153 1e-35
UniRef50_Q5KNK5 Cluster: Cysteine synthase; n=1; Filobasidiella ... 152 2e-35
UniRef50_Q8YXP3 Cluster: Cysteine synthase; n=2; Nostoc sp. PCC ... 151 4e-35
UniRef50_Q014R8 Cluster: Cysteine synthase; n=3; Ostreococcus|Re... 151 4e-35
UniRef50_A3ERN7 Cluster: Cysteine synthase; n=3; Bacteria|Rep: C... 151 5e-35
UniRef50_Q44004 Cluster: Cysteine synthase (EC 2.5.1.47) (O-acet... 149 2e-34
UniRef50_Q9PF47 Cluster: Cysteine synthase; n=14; Gammaproteobac... 148 3e-34
UniRef50_Q4Q159 Cluster: Cysteine synthase, putative; n=4; cellu... 147 6e-34
UniRef50_A1S012 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 146 8e-34
UniRef50_Q5V5J3 Cluster: Cysteine synthase; n=1; Haloarcula mari... 146 1e-33
UniRef50_Q018U5 Cluster: COG0031: Cysteine synthase; n=5; cellul... 145 2e-33
UniRef50_A7Q973 Cluster: Chromosome chr19 scaffold_66, whole gen... 145 2e-33
UniRef50_Q016B2 Cluster: Cysteine synthase; n=2; Ostreococcus|Re... 144 5e-33
UniRef50_A3UA05 Cluster: Cysteine synthase; n=1; Croceibacter at... 142 1e-32
UniRef50_A7D2W0 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 141 3e-32
UniRef50_Q934D2 Cluster: Cysteine synthase; n=1; Streptomyces av... 140 9e-32
UniRef50_P45040 Cluster: Cysteine synthase (EC 2.5.1.47) (O-acet... 140 9e-32
UniRef50_Q88B28 Cluster: Cysteine synthase; n=1; Pseudomonas syr... 139 1e-31
UniRef50_P63874 Cluster: Cysteine synthase B (EC 2.5.1.47) (O-ac... 139 1e-31
UniRef50_Q6L2R6 Cluster: Cysteine synthase; n=5; cellular organi... 138 2e-31
UniRef50_Q216V8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 138 3e-31
UniRef50_P55708 Cluster: Putative cysteine synthase (EC 2.5.1.47... 138 3e-31
UniRef50_P29848 Cluster: Cysteine synthase B (EC 2.5.1.47) (O-ac... 138 4e-31
UniRef50_Q5QVH4 Cluster: Cysteine synthase; n=6; Gammaproteobact... 137 6e-31
UniRef50_O67507 Cluster: Cysteine synthase (EC 2.5.1.47) (O-acet... 137 6e-31
UniRef50_A2R5Q4 Cluster: Catalytic activity: O3-acetyl-L-serine ... 136 8e-31
UniRef50_Q0LP40 Cluster: Cysteine synthase; n=3; Bacteria|Rep: C... 136 1e-30
UniRef50_O16284 Cluster: Cysteine synthase; n=4; Caenorhabditis|... 135 2e-30
UniRef50_A3UUR9 Cluster: Probable cysteine synthase A; n=1; Vibr... 134 4e-30
UniRef50_A0Z0S2 Cluster: Cysteine synthase; n=1; marine gamma pr... 134 6e-30
UniRef50_A7HK96 Cluster: Pyridoxal-5'-phosphate-dependent protei... 132 1e-29
UniRef50_Q8KNS8 Cluster: Pyridoxal-phosphate dependent enzyme; n... 131 3e-29
UniRef50_Q747V7 Cluster: Cysteine synthase B; n=11; cellular org... 130 5e-29
UniRef50_Q8KB68 Cluster: Cysteine synthase/cystathionine beta-sy... 130 9e-29
UniRef50_A4M0Z4 Cluster: Cysteine synthase; n=2; Bacteria|Rep: C... 129 2e-28
UniRef50_Q8FPS2 Cluster: Cysteine synthase; n=3; Corynebacterium... 128 2e-28
UniRef50_Q98DL3 Cluster: Cysteine synthase; n=19; cellular organ... 128 4e-28
UniRef50_Q881D4 Cluster: Pyridoxal-phosphate dependent enzyme fa... 126 2e-27
UniRef50_Q48J16 Cluster: Pyridoxal-phosphate dependent enzyme fa... 125 2e-27
UniRef50_A0TSM7 Cluster: Cysteine synthase; n=3; Burkholderia ce... 124 4e-27
UniRef50_Q7NMK0 Cluster: Cysteine synthase; n=3; Bacteria|Rep: C... 120 6e-26
UniRef50_Q2JV56 Cluster: Cysteine synthase; n=6; Bacteria|Rep: C... 120 6e-26
UniRef50_P87131 Cluster: Cysteine synthase 2 (EC 2.5.1.47) (O-ac... 120 8e-26
UniRef50_A3ZS86 Cluster: Cysteine synthase; n=6; Bacteria|Rep: C... 120 1e-25
UniRef50_Q9YCN5 Cluster: Cystathionine beta-synthase; n=1; Aerop... 117 5e-25
UniRef50_A0Q7G8 Cluster: Cysteine synthase; n=11; Francisella tu... 117 7e-25
UniRef50_A2BJ27 Cluster: Cysteine synthase; n=1; Hyperthermus bu... 116 9e-25
UniRef50_P53206 Cluster: Putative cysteine synthase (EC 2.5.1.47... 115 3e-24
UniRef50_A0ITV5 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 114 4e-24
UniRef50_A3SLF6 Cluster: Cysteine synthase; n=2; Bacteria|Rep: C... 114 5e-24
UniRef50_A1ZVV4 Cluster: Cysteine synthase (O-acetylserine sulfh... 111 3e-23
UniRef50_A2FS17 Cluster: Cysteine synthase; n=1; Trichomonas vag... 111 3e-23
UniRef50_A6TNQ8 Cluster: Pyridoxal-5'-phosphate-dependent protei... 111 5e-23
UniRef50_A3Q5A0 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 108 3e-22
UniRef50_Q08Q19 Cluster: Pyridoxal-phosphate dependent enzyme; n... 107 6e-22
UniRef50_A6FEJ8 Cluster: Cysteine synthase, O-acetylserine (Thio... 106 1e-21
UniRef50_Q5IWX8 Cluster: Plastid cysteine synthase; n=1; Prototh... 106 1e-21
UniRef50_Q2RYV2 Cluster: Cysteine synthase B; n=1; Salinibacter ... 106 1e-21
UniRef50_Q1AYU1 Cluster: Cysteine synthase; n=4; Bacteria|Rep: C... 105 2e-21
UniRef50_A0E1N6 Cluster: Cysteine synthase; n=2; Oligohymenophor... 105 3e-21
UniRef50_Q8F4E4 Cluster: Cysteine synthase B; n=4; Leptospira|Re... 104 4e-21
UniRef50_Q6A875 Cluster: Cystathionine beta-synthase; n=1; Propi... 104 4e-21
UniRef50_A2FS16 Cluster: Cysteine synthase; n=1; Trichomonas vag... 103 9e-21
UniRef50_Q93H29 Cluster: CysK-like protein; n=3; Actinomycetales... 102 2e-20
UniRef50_A7DSI8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 102 2e-20
UniRef50_Q2QD00 Cluster: Zwa5A; n=2; Bacillus cereus group|Rep: ... 99 1e-19
UniRef50_Q0C5S8 Cluster: Cysteine synthase/cystathionine beta-sy... 99 2e-19
UniRef50_Q1IBI7 Cluster: Putative Cysteine synthase; n=1; Pseudo... 98 5e-19
UniRef50_Q9HRP3 Cluster: Cysteine synthase; n=2; Halobacteriacea... 96 2e-18
UniRef50_Q0DBH7 Cluster: Os06g0564400 protein; n=4; Oryza sativa... 95 4e-18
UniRef50_Q95PN6 Cluster: Cystathionine beta-synthase; n=1; Oster... 93 1e-17
UniRef50_Q50059 Cluster: CysS; n=1; Mycobacterium leprae|Rep: Cy... 92 3e-17
UniRef50_Q0UV41 Cluster: Putative uncharacterized protein; n=1; ... 92 3e-17
UniRef50_Q54312 Cluster: Cystathione synthase; n=1; Streptomyces... 89 2e-16
UniRef50_A7D608 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 89 2e-16
UniRef50_A6QZJ2 Cluster: Cysteine synthase; n=1; Ajellomyces cap... 88 4e-16
UniRef50_Q0AFB1 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 88 5e-16
UniRef50_Q8TZW7 Cluster: Cysteine synthase; n=4; Archaea|Rep: Cy... 86 2e-15
UniRef50_A3AFH4 Cluster: Cysteine synthase; n=3; Oryza sativa|Re... 85 3e-15
UniRef50_Q4PCE5 Cluster: Cysteine synthase; n=1; Ustilago maydis... 85 3e-15
UniRef50_A6DD26 Cluster: Cysteine synthase; n=1; Caminibacter me... 85 3e-15
UniRef50_Q5KCX2 Cluster: Cysteine synthase; n=2; Filobasidiella ... 85 5e-15
UniRef50_Q0RLF9 Cluster: Putative uncharacterized protein; n=1; ... 84 6e-15
UniRef50_A3KIP2 Cluster: Putative pyridoxal-phosphate dependent ... 84 6e-15
UniRef50_Q98PA8 Cluster: Cysteine synthase; n=2; Rhizobiales|Rep... 84 8e-15
UniRef50_Q9LG24 Cluster: Cysteine synthase; n=4; core eudicotyle... 83 2e-14
UniRef50_Q5YWN0 Cluster: Putative uncharacterized protein; n=1; ... 82 2e-14
UniRef50_Q59918 Cluster: Cysteine synthase (EC 2.5.1.47) (O-acet... 82 2e-14
UniRef50_A6FZP3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 82 3e-14
UniRef50_Q6L0G4 Cluster: Cysteine synthase; n=2; Thermoplasmatal... 81 8e-14
UniRef50_Q7UFE1 Cluster: Cysteine synthase B; n=3; Bacteria|Rep:... 80 1e-13
UniRef50_A0G7W8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 80 1e-13
UniRef50_Q2W8G8 Cluster: Cysteine synthase; n=1; Magnetospirillu... 79 2e-13
UniRef50_A6YEH3 Cluster: CmnB; n=1; Saccharothrix mutabilis subs... 79 2e-13
UniRef50_UPI0000ECD4F3 Cluster: UPI0000ECD4F3 related cluster; n... 78 5e-13
UniRef50_A2BN44 Cluster: Cysteine synthase; n=3; Thermoprotei|Re... 78 5e-13
UniRef50_Q980F2 Cluster: Cysteine synthase B; n=4; Sulfolobaceae... 77 7e-13
UniRef50_Q3JSA1 Cluster: Cysteine synthase; n=6; Burkholderia ps... 76 2e-12
UniRef50_Q97B69 Cluster: Cysteine synthase; n=2; Thermoplasma|Re... 75 5e-12
UniRef50_Q2RGZ3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 73 2e-11
UniRef50_A3KFG2 Cluster: DabA; n=1; Actinoplanes friuliensis|Rep... 73 2e-11
UniRef50_Q62J64 Cluster: Cysteine synthase/cystathionine beta-sy... 68 6e-10
UniRef50_A2R0U9 Cluster: Catalytic activity: O3-acetyl-L-serine ... 68 6e-10
UniRef50_Q6WZB1 Cluster: 2,3-diaminopropionate synthase; n=2; St... 67 7e-10
UniRef50_Q0D1N1 Cluster: Cysteine synthase 2; n=4; Eurotiomyceti... 65 3e-09
UniRef50_A1D9N4 Cluster: Cysteine synthase B, putative; n=3; Pez... 65 3e-09
UniRef50_A3ZYZ6 Cluster: Threonine synthase; n=2; Planctomycetac... 65 4e-09
UniRef50_Q981U9 Cluster: Cysteine synthase; n=2; Mesorhizobium l... 64 7e-09
UniRef50_A6LNR7 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 63 2e-08
UniRef50_Q8CZI2 Cluster: Cysteine synthase; n=9; Bacteria|Rep: C... 62 2e-08
UniRef50_Q60B84 Cluster: Threonine synthase; n=7; Gammaproteobac... 58 3e-07
UniRef50_Q0UAH5 Cluster: Putative uncharacterized protein; n=1; ... 58 5e-07
UniRef50_Q58860 Cluster: Probable threonine synthase; n=19; Arch... 56 1e-06
UniRef50_Q0C2B7 Cluster: Pyridoxal-phosphate-dependent enzyme; n... 56 2e-06
UniRef50_A2BKW1 Cluster: Threonine synthase; n=1; Hyperthermus b... 56 2e-06
UniRef50_A6NZW4 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06
UniRef50_Q5KGT7 Cluster: Serine family amino acid catabolism-rel... 56 2e-06
UniRef50_A6R3N4 Cluster: Predicted protein; n=1; Ajellomyces cap... 56 2e-06
UniRef50_Q0W7Y3 Cluster: Threonine synthase; n=1; uncultured met... 55 3e-06
UniRef50_Q9PH18 Cluster: Cysteine synthase; n=8; Bacteria|Rep: C... 55 4e-06
UniRef50_Q3EKD4 Cluster: Cysteine synthase; n=2; Bacillus cereus... 54 6e-06
UniRef50_Q54ZW3 Cluster: Threonine ammonia-lyase; n=2; Dictyoste... 54 7e-06
UniRef50_A2R2J5 Cluster: Catalytic activity: O3-acetyl-L-serine+... 54 7e-06
UniRef50_Q9K7E3 Cluster: Threonine synthase; n=51; cellular orga... 54 7e-06
UniRef50_Q4PAX1 Cluster: Putative uncharacterized protein; n=1; ... 53 1e-05
UniRef50_A6RLV9 Cluster: Putative uncharacterized protein; n=2; ... 53 1e-05
UniRef50_Q2CJ64 Cluster: Threonine synthase; n=1; Oceanicola gra... 53 2e-05
UniRef50_A1HTF2 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 53 2e-05
UniRef50_Q0SFD0 Cluster: Probable threonine ammonia-lyase; n=1; ... 52 2e-05
UniRef50_A4JPB4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 52 3e-05
UniRef50_Q9EX46 Cluster: Putative cysteine synthase; n=4; Strept... 52 4e-05
UniRef50_Q024T6 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 50 1e-04
UniRef50_A4FDP6 Cluster: Cysteine synthase A; n=1; Saccharopolys... 50 1e-04
UniRef50_Q9UZV8 Cluster: ThrC threonine synthase; n=5; Archaea|R... 50 1e-04
UniRef50_Q89XS1 Cluster: Cysteine synthase/cystathionine beta-sy... 50 2e-04
UniRef50_Q97ZT5 Cluster: Threonine synthase; n=6; Archaea|Rep: T... 50 2e-04
UniRef50_A3H5T4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 50 2e-04
UniRef50_A3DMX4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 50 2e-04
UniRef50_Q7NS30 Cluster: Probable cysteine synthase B; n=1; Chro... 49 2e-04
UniRef50_Q2IRQ4 Cluster: Threonine synthase; n=1; Rhodopseudomon... 49 2e-04
UniRef50_Q6C6D8 Cluster: Yarrowia lipolytica chromosome E of str... 49 3e-04
UniRef50_Q1DVD5 Cluster: Putative uncharacterized protein; n=1; ... 49 3e-04
UniRef50_A3DKY8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 49 3e-04
UniRef50_Q67LA4 Cluster: Threonine synthase; n=1; Symbiobacteriu... 48 4e-04
UniRef50_A6C9B2 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 48 4e-04
UniRef50_A0GA25 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 48 4e-04
UniRef50_P74193 Cluster: Threonine synthase; n=123; Bacteria|Rep... 48 4e-04
UniRef50_Q12EY4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 48 5e-04
UniRef50_Q9Y9K2 Cluster: Threonine synthase; n=1; Aeropyrum pern... 48 5e-04
UniRef50_UPI00015BAF2C Cluster: L-threonine synthase; n=1; Ignic... 48 6e-04
UniRef50_Q5KZ40 Cluster: Threonine synthase; n=7; Bacteria|Rep: ... 48 6e-04
UniRef50_A6G3T5 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 48 6e-04
UniRef50_Q965I8 Cluster: Putative uncharacterized protein T25D3.... 48 6e-04
UniRef50_A4R1F1 Cluster: Putative uncharacterized protein; n=3; ... 48 6e-04
UniRef50_Q4LEC5 Cluster: Threonine synthase; n=1; uncultured cre... 48 6e-04
UniRef50_Q5K9Z3 Cluster: L-serine ammonia-lyase, putative; n=2; ... 47 9e-04
UniRef50_A3LQ20 Cluster: Predicted protein; n=5; Saccharomycetal... 47 9e-04
UniRef50_Q8RAI2 Cluster: Threonine synthase; n=14; Bacteria|Rep:... 47 0.001
UniRef50_Q64CL8 Cluster: Threonine synthase; n=1; uncultured arc... 47 0.001
UniRef50_A6NQ75 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_A3DKP7 Cluster: Threonine synthase; n=1; Staphylothermu... 46 0.001
UniRef50_A6VZW2 Cluster: Pyridoxal-5'-phosphate-dependent protei... 46 0.002
UniRef50_A1CH94 Cluster: L-serine dehydratase; n=8; Trichocomace... 46 0.002
UniRef50_Q9YBW2 Cluster: Threonine synthase; n=1; Aeropyrum pern... 46 0.002
UniRef50_UPI00015B8BD6 Cluster: UPI00015B8BD6 related cluster; n... 46 0.003
UniRef50_A7DMC4 Cluster: Threonine dehydratase; n=1; Candidatus ... 46 0.003
UniRef50_Q8CZG4 Cluster: Threonine dehydratase; n=20; Proteobact... 45 0.003
UniRef50_Q2PGG3 Cluster: Serine racemase; n=8; Magnoliophyta|Rep... 45 0.003
UniRef50_A3H9X3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 45 0.003
UniRef50_Q8NRR7 Cluster: Threonine dehydratase; n=4; Actinomycet... 45 0.005
UniRef50_Q89KX3 Cluster: Bll4777 protein; n=8; Bacteria|Rep: Bll... 45 0.005
UniRef50_Q890M3 Cluster: Threonine dehydratase; n=13; Firmicutes... 45 0.005
UniRef50_A3DLX2 Cluster: Threonine dehydratase; n=2; Thermoprote... 45 0.005
UniRef50_O94634 Cluster: Threonine ammonia-lyase; n=1; Schizosac... 44 0.006
UniRef50_Q124A5 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 44 0.008
UniRef50_Q4PDX1 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008
UniRef50_A1S0F3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 44 0.008
UniRef50_Q1YQF2 Cluster: Putative threonine dehydratase; n=1; ga... 44 0.011
UniRef50_Q9V0P1 Cluster: Pyridoxal phosphate dependent enzyme; n... 44 0.011
UniRef50_Q97CB2 Cluster: Threonine deaminase; n=4; Thermoplasmat... 44 0.011
UniRef50_Q8ZVF0 Cluster: Threonine dehydratase; n=6; Thermoprote... 44 0.011
UniRef50_P25379 Cluster: Catabolic L-serine/threonine dehydratas... 44 0.011
UniRef50_Q96GA7 Cluster: Serine dehydratase-like; n=29; Eumetazo... 44 0.011
UniRef50_Q92HZ2 Cluster: Threonine dehydratase [EC:4.2.1.16]; n=... 43 0.014
UniRef50_Q6CV26 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 43 0.014
UniRef50_Q9ZSS6 Cluster: Threonine dehydratase biosynthetic, chl... 43 0.014
UniRef50_UPI0000E46AA9 Cluster: PREDICTED: hypothetical protein;... 43 0.018
UniRef50_Q897Z9 Cluster: Threonine synthase; n=3; cellular organ... 43 0.018
UniRef50_Q4WJF6 Cluster: L-serine dehydratase, putative; n=4; Tr... 43 0.018
UniRef50_Q0UFK8 Cluster: Putative uncharacterized protein; n=1; ... 43 0.018
UniRef50_A0RZ81 Cluster: Threonine synthase; n=3; Crenarchaeota|... 43 0.018
UniRef50_Q2CF35 Cluster: Threonine synthase; n=1; Oceanicola gra... 42 0.024
UniRef50_Q4P450 Cluster: Putative uncharacterized protein; n=2; ... 42 0.024
UniRef50_UPI0000382529 Cluster: COG0031: Cysteine synthase; n=1;... 42 0.032
UniRef50_A6TUF4 Cluster: GCN5-related N-acetyltransferase; n=1; ... 42 0.043
UniRef50_Q01DW9 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 42 0.043
UniRef50_A3H8E6 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 42 0.043
UniRef50_A0RTS2 Cluster: Cysteine synthase; n=2; Thermoprotei|Re... 42 0.043
UniRef50_Q01PK6 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 41 0.056
UniRef50_A6G5U3 Cluster: Putative amino-acid dehydratase; n=1; P... 41 0.056
UniRef50_Q2L695 Cluster: Aspartate racemase; n=3; Coelomata|Rep:... 41 0.056
UniRef50_Q9HNH0 Cluster: Threonine synthase; n=3; Halobacteriace... 41 0.056
UniRef50_Q5V5Z0 Cluster: Threonine dehydratase; n=4; cellular or... 41 0.056
UniRef50_Q89E51 Cluster: Bll7236 protein; n=3; Proteobacteria|Re... 41 0.074
UniRef50_Q7WD36 Cluster: Threonine synthase; n=2; Bordetella|Rep... 41 0.074
UniRef50_A4M845 Cluster: Threonine synthase; n=2; Bacteria|Rep: ... 41 0.074
UniRef50_P17324 Cluster: L-serine dehydratase; n=3; Saccharomyce... 41 0.074
UniRef50_Q4SDW2 Cluster: Chromosome undetermined SCAF14629, whol... 40 0.098
UniRef50_Q39HS0 Cluster: L-serine ammonia-lyase; n=20; Proteobac... 40 0.098
UniRef50_Q0LPK7 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 40 0.098
UniRef50_Q9HKU8 Cluster: Threonine synthase related protein; n=2... 40 0.098
UniRef50_Q6MP14 Cluster: Threonine ammonia-lyase; n=1; Bdellovib... 40 0.13
UniRef50_Q3V7H0 Cluster: Threonine dehydratase, biosynthetic; n=... 40 0.13
UniRef50_Q2JFB2 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 40 0.13
UniRef50_Q19374 Cluster: Putative pyridoxal-phosphate dependent ... 40 0.13
UniRef50_Q5V2S7 Cluster: Threonine dehydratase; n=1; Haloarcula ... 40 0.17
UniRef50_UPI00006CFBDA Cluster: hypothetical protein TTHERM_0052... 39 0.23
UniRef50_Q6D6V9 Cluster: Putative threonine dehydratase cataboli... 39 0.23
UniRef50_Q5KZL0 Cluster: Threonine dehydratase; n=6; Bacteria|Re... 39 0.23
UniRef50_Q025L3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 39 0.23
UniRef50_A7CMA2 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 39 0.23
UniRef50_A0RVV9 Cluster: Threonine dehydratase; n=1; Cenarchaeum... 39 0.23
UniRef50_Q9GZT4 Cluster: Serine racemase; n=27; Eumetazoa|Rep: S... 39 0.23
UniRef50_UPI000049867D Cluster: threonine dehydratase; n=2; Enta... 39 0.30
UniRef50_Q74FW6 Cluster: Threonine dehydratase; n=7; Bacteria|Re... 39 0.30
UniRef50_Q46N34 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 39 0.30
UniRef50_A1KYC1 Cluster: Serine dehydratase; n=1; Aplysia califo... 39 0.30
UniRef50_Q5AYI2 Cluster: Putative uncharacterized protein; n=1; ... 39 0.30
UniRef50_Q6L077 Cluster: Threonine synthase; n=2; Thermoplasmata... 39 0.30
UniRef50_UPI0000498F4D Cluster: threonine dehydratase; n=1; Enta... 38 0.40
UniRef50_A6VNW0 Cluster: Pyridoxal-5'-phosphate-dependent protei... 38 0.40
UniRef50_Q2SDR6 Cluster: Threonine dehydratase; n=1; Hahella che... 38 0.53
UniRef50_A5V3K5 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 38 0.53
UniRef50_Q93968 Cluster: Putative uncharacterized protein; n=2; ... 38 0.53
UniRef50_Q54HH2 Cluster: Threonine ammonia-lyase; n=1; Dictyoste... 38 0.53
UniRef50_Q4DZF5 Cluster: Threonine dehydratase-like, putative; n... 38 0.53
UniRef50_Q18JW2 Cluster: Threonine synthase; n=1; Haloquadratum ... 38 0.53
UniRef50_UPI00005A5A28 Cluster: PREDICTED: similar to peroxisoma... 38 0.69
UniRef50_Q5Z093 Cluster: Putative amino acid deaminase; n=1; Noc... 38 0.69
UniRef50_Q3KDV0 Cluster: Threonine synthase; n=2; Pseudomonas|Re... 38 0.69
UniRef50_Q1QTY8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 38 0.69
UniRef50_Q0AVH3 Cluster: Putative uncharacterized protein precur... 38 0.69
UniRef50_A7SV73 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.69
UniRef50_Q5WD43 Cluster: Threonine synthase; n=2; Bacillus|Rep: ... 37 0.92
UniRef50_Q5H6D8 Cluster: Threonine dehydratase; n=7; Xanthomonad... 37 0.92
UniRef50_Q39R38 Cluster: Threonine dehydratase II; n=2; Geobacte... 37 0.92
UniRef50_Q2JI28 Cluster: Threonine synthase; n=38; cellular orga... 37 0.92
UniRef50_A6LMM2 Cluster: Threonine synthase; n=1; Thermosipho me... 37 0.92
UniRef50_A6G2Y3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 37 0.92
UniRef50_A5G4I9 Cluster: Pyridoxal-phosphate dependent TrpB-like... 37 0.92
UniRef50_Q7R3A5 Cluster: GLP_111_51210_48397; n=3; Hexamitidae|R... 37 0.92
UniRef50_Q8U4P9 Cluster: Threonine synthase; n=1; Pyrococcus fur... 37 0.92
UniRef50_Q3KAE0 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 37 1.2
UniRef50_Q0LGE1 Cluster: Threonine synthase; n=1; Herpetosiphon ... 37 1.2
UniRef50_Q98PA7 Cluster: Threonine synthase homolog; n=2; Rhizob... 36 1.6
UniRef50_Q82IF6 Cluster: Putative threonine synthase; n=1; Strep... 36 1.6
UniRef50_Q47P43 Cluster: Threonine ammonia-lyase; n=1; Thermobif... 36 1.6
UniRef50_Q1GLC9 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 36 1.6
UniRef50_P37946 Cluster: Threonine dehydratase biosynthetic; n=5... 36 1.6
UniRef50_Q9RYW1 Cluster: Oxidoreductase, short-chain dehydrogena... 36 2.1
UniRef50_Q89UK3 Cluster: Bll1413 protein; n=11; Bacteria|Rep: Bl... 36 2.1
UniRef50_A4F8G4 Cluster: Threonine synthase homolog; n=1; Saccha... 36 2.1
UniRef50_A2FRC0 Cluster: Threonine dehydratase family protein; n... 36 2.1
UniRef50_A2D811 Cluster: Pyridoxal-phosphate dependent enzyme fa... 36 2.1
UniRef50_Q7VHR7 Cluster: Threonine dehydratase; n=20; Epsilonpro... 36 2.8
UniRef50_Q4KB39 Cluster: Serine/threonine dehydratase family pro... 36 2.8
UniRef50_Q9F7T0 Cluster: Predicted threonine dehydratase; n=1; u... 36 2.8
UniRef50_Q3Y0B2 Cluster: Transcriptional activator Rgg/GadR/MutR... 36 2.8
UniRef50_Q1GC73 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 36 2.8
UniRef50_A5VDW1 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 36 2.8
UniRef50_Q2U361 Cluster: Threonine dehydratase; n=2; cellular or... 36 2.8
UniRef50_Q985M4 Cluster: Serine/threonine dehydratase; n=1; Meso... 35 3.7
UniRef50_Q8G466 Cluster: Catabolic threonine dehydratase; n=4; B... 35 3.7
UniRef50_Q72GY8 Cluster: Threonine dehydratase; n=2; Thermus the... 35 3.7
UniRef50_A0JU39 Cluster: Threonine dehydratase; n=10; Actinobact... 35 3.7
UniRef50_Q980P1 Cluster: Threonine dehydratase catabolic; n=4; S... 35 3.7
UniRef50_P46493 Cluster: Threonine dehydratase biosynthetic; n=4... 35 3.7
UniRef50_Q6KIJ0 Cluster: Alanine dehydrogenase; n=1; Mycoplasma ... 35 4.9
UniRef50_Q5E4U3 Cluster: Threonine synthase; n=1; Vibrio fischer... 35 4.9
UniRef50_Q8RTR1 Cluster: Alcohol dehydrogenase; n=69; Proteobact... 35 4.9
UniRef50_Q1GTV4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 35 4.9
UniRef50_A1ZHE9 Cluster: Serine racemase; n=1; Microscilla marin... 35 4.9
UniRef50_A1G2S3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 35 4.9
UniRef50_Q7RN74 Cluster: Similar to yeast ncl1-related; n=3; Pla... 35 4.9
UniRef50_P55664 Cluster: Putative threonine dehydratase; n=31; P... 35 4.9
UniRef50_P00927 Cluster: Threonine dehydratase, mitochondrial pr... 35 4.9
UniRef50_Q89R30 Cluster: Bll2942 protein; n=12; Bacteria|Rep: Bl... 34 6.5
UniRef50_Q2RWP4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 34 6.5
UniRef50_A0K061 Cluster: Rhamnulose-1-phosphate aldolase/alcohol... 34 6.5
UniRef50_A0D3F4 Cluster: Chromosome undetermined scaffold_36, wh... 34 6.5
UniRef50_Q9C2I1 Cluster: Related to L-serine dehydratase; n=1; N... 34 6.5
UniRef50_Q6L1K3 Cluster: Pyridoxal-phosphate dependent enzyme; n... 34 6.5
UniRef50_UPI00006CA830 Cluster: Pyridoxal-phosphate dependent en... 34 8.6
UniRef50_A4QN59 Cluster: MGC162269 protein; n=3; Clupeocephala|R... 34 8.6
UniRef50_Q0K4H3 Cluster: Threonine synthase; n=1; Ralstonia eutr... 34 8.6
UniRef50_Q0AQJ8 Cluster: Threonine dehydratase; n=1; Maricaulis ... 34 8.6
UniRef50_A0J1S9 Cluster: Pyridoxal-5'-phosphate-dependent enzyme... 34 8.6
UniRef50_P20506 Cluster: Threonine dehydratase biosynthetic; n=2... 34 8.6
UniRef50_P28360 Cluster: Homeobox protein MSX-1; n=119; Eumetazo... 34 8.6
>UniRef50_Q9VRD9 Cluster: CG1753-PA, isoform A; n=8;
Pancrustacea|Rep: CG1753-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 522
Score = 337 bits (828), Expect = 4e-91
Identities = 174/329 (52%), Positives = 217/329 (65%), Gaps = 8/329 (2%)
Query: 9 RNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQK 68
R +I NILE IG TPLV+LN IP G+ECEM+AKCEF+NPGGS+KDRI Y MV +A++
Sbjct: 42 RQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEE 101
Query: 69 SGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
G+ K G IEPTSGNTGIG+A+A AV G+ C IV P+K S+EK+S + LGA++++TP
Sbjct: 102 QGLLKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTP 161
Query: 129 AMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIX 187
A ++S E + VA++ E PN+I DQY+N NP HY+ TA EIL L VDMI
Sbjct: 162 TEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIV 221
Query: 188 XXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLI-----FGEGPADLYFVEGIGGDFVP 242
+K+KE+ P C IV VDP GS++ + Y VEGIG DF P
Sbjct: 222 VSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPP 281
Query: 243 DVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRV 302
V D +V+D K D D F MSR + +EGLLCGGSSG AM +A+ A+KL G+R
Sbjct: 282 TVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHARKLK--KGQRC 339
Query: 303 VVILPDGIRNYMTKFVCDQWMEAHLFKEP 331
VVILPDGIRNYMTKFV D WMEA FKEP
Sbjct: 340 VVILPDGIRNYMTKFVSDNWMEARNFKEP 368
>UniRef50_P35520 Cluster: Cystathionine beta-synthase; n=57;
cellular organisms|Rep: Cystathionine beta-synthase -
Homo sapiens (Human)
Length = 551
Score = 319 bits (783), Expect = 1e-85
Identities = 159/319 (49%), Positives = 215/319 (67%), Gaps = 8/319 (2%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
+I +IL+ IGDTP+VR+N+I K +GL+CE+ AKCEF N GGS+KDRIS M+ +A++ G
Sbjct: 75 KILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDG 134
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
K G IEPTSGNTGIG+ALA AV G+ C IV P+K S EK+ + LGAE+V+TP
Sbjct: 135 TLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTN 194
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXX 189
A ++S E + VA R E PN+ DQY+N NP HY+ TA+EIL +DM+
Sbjct: 195 ARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVAS 254
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLI-----FGEGPADLYFVEGIGGDFVPDV 244
A+K+KEKCP C I+ VDP+GS++ + Y VEGIG DF+P V
Sbjct: 255 VGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTV 314
Query: 245 LDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVV 304
LD++V+DK K ND +AF +R +I +EGLLCGGS+G+ + A++AA++L G+R VV
Sbjct: 315 LDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ--EGQRCVV 372
Query: 305 ILPDGIRNYMTKFVCDQWM 323
ILPD +RNYMTKF+ D+WM
Sbjct: 373 ILPDSVRNYMTKFLSDRWM 391
>UniRef50_Q9YHU3 Cluster: Cystathionine beta-synthetase; n=14;
Eukaryota|Rep: Cystathionine beta-synthetase - Fugu
rubripes (Japanese pufferfish) (Takifugu rubripes)
Length = 585
Score = 312 bits (767), Expect = 9e-84
Identities = 162/323 (50%), Positives = 213/323 (65%), Gaps = 7/323 (2%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I NIL IG+TPLVRLN+IPK +G++C++ KCEF + GGSIKDRI+ MV +A+++G+
Sbjct: 80 ILPNILGNIGNTPLVRLNKIPKQFGIKCDILVKCEFFSAGGSIKDRIALRMVEDAERAGL 139
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K G IEPTSGNTGIG+AL +V G+ C I PD+ S EK+ + LGAEVV TP+ A
Sbjct: 140 LKPGDTIIEPTSGNTGIGLALVASVKGYRCVITMPDRMSMEKVDVLKALGAEVVHTPSSA 199
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXX 190
P++S E + +A + PN+ DQY+N NP HY+ TAEEIL +DM+
Sbjct: 200 PFDSPESQVGMAWCLKNKIPNSHILDQYRNASNPLAHYDATAEEILEQCDGKLDMLVAGI 259
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF--GEGPADLYFVEGIGGDFVPDVLDKS 248
A+K+KEKCP IV VDP+GSL+ + Y VEGIG DFVP VLDKS
Sbjct: 260 GTGGTLTGVARKLKEKCP--TIVAVDPEGSLLIHSDDHCKSSYEVEGIGYDFVPTVLDKS 317
Query: 249 VIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPD 308
++D K ND + FNMSR +I+ EGLLCGGSSG+AM +A++ A+ L G+R VVIL D
Sbjct: 318 LVDYFYKVNDKETFNMSRRLIRDEGLLCGGSSGSAMAAAVKVAQHLK--EGQRCVVILAD 375
Query: 309 GIRNYMTKFVCDQWMEAHLFKEP 331
+RNYM+KF+ D+WM F P
Sbjct: 376 SVRNYMSKFLSDKWMSEKGFLVP 398
>UniRef50_P46794 Cluster: Cystathionine beta-synthase; n=5;
Eukaryota|Rep: Cystathionine beta-synthase -
Dictyostelium discoideum (Slime mold)
Length = 497
Score = 299 bits (733), Expect = 1e-79
Identities = 151/333 (45%), Positives = 214/333 (64%), Gaps = 9/333 (2%)
Query: 4 SRSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMV 63
+R + I +NIL+ IG TPLVR+N++ D LECE+ AKCEF N GGS+KDRI + M+
Sbjct: 24 TRRTPKKLIMDNILDNIGGTPLVRVNKVSSD--LECELVAKCEFFNAGGSVKDRIGHRMI 81
Query: 64 LEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAE 123
++A++SG K G IEPTSGNTGIG+AL A+ G+ I P+K S EK+ + LG E
Sbjct: 82 VDAEESGRIKKGDTLIEPTSGNTGIGLALTAAIKGYKMIITLPEKMSQEKVDVLKALGGE 141
Query: 124 VVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-D 182
+++TP A +++ E + VAK+ E PN+ DQY N NP HY+ TAEE+L
Sbjct: 142 IIRTPTEAAFDAPESHIGVAKKLNSEIPNSHILDQYGNPSNPLAHYDGTAEELLEQCEGK 201
Query: 183 VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG----EGPADLYFVEGIGG 238
+DMI A+K+KE+ P CI+V VDP GS++ Y +EGIG
Sbjct: 202 IDMIVCTAGTGGTITGIARKIKERLPNCIVVGVDPHGSILAQPESLNNTNKSYKIEGIGY 261
Query: 239 DFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGA 298
DF+P+VL++ ++D+ K +D ++F M+R +IK+EGLLC GSSG+AM+ A+ AAK+L
Sbjct: 262 DFIPNVLERKLVDQWIKTDDKESFIMARRLIKEEGLLCAGSSGSAMVGALLAAKQLK--K 319
Query: 299 GKRVVVILPDGIRNYMTKFVCDQWMEAHLFKEP 331
G+R VV+L D IRNYMTK + D W+ + F +P
Sbjct: 320 GQRCVVLLADSIRNYMTKHLNDDWLVDNGFVDP 352
>UniRef50_A0DFI6 Cluster: Chromosome undetermined scaffold_49, whole
genome shotgun sequence; n=4; cellular organisms|Rep:
Chromosome undetermined scaffold_49, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 491
Score = 295 bits (725), Expect = 1e-78
Identities = 150/328 (45%), Positives = 202/328 (61%), Gaps = 6/328 (1%)
Query: 2 SNSRSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYT 61
S+S+ +IY++ L+ IG TP++RLN+IPK++GL+CE+ KCEFVN GSIKDRI
Sbjct: 28 SHSQFVPFKKIYSDALDAIGHTPMIRLNKIPKEFGLKCEVLVKCEFVNVAGSIKDRIGVR 87
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
M+++A+K G G +E TSGNTG+G+ALA AV G+ I P+K S EK ++ LG
Sbjct: 88 MIVDAEKQGRLGPGKSIVEATSGNTGVGLALACAVKGYPLYITMPEKMSQEKQDVLTGLG 147
Query: 122 AEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP 181
A+V++TP A W E + VAKR E+P+ I DQY N NP HYE TAEEIL
Sbjct: 148 AKVIRTPTEAAWYEPESLIQVAKRMAAENPDIILLDQYSNPSNPLAHYEGTAEEILWACD 207
Query: 182 D-VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLI-----FGEGPADLYFVEG 235
D +D I +K+ E+ P C ++ VDP GS + + Y VEG
Sbjct: 208 DKLDAIVMSTGTGGTVTGVGRKIHERVPGCKVIAVDPFGSDLALPPEINKTDIKSYKVEG 267
Query: 236 IGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLN 295
IG DF+P LD++ +D K ND D+ NM+R+++ EGLLCGGSSGA + A AK N
Sbjct: 268 IGYDFIPKALDRTEVDFWIKSNDKDSLNMARKLMAVEGLLCGGSSGANVWGAFEWAKSQN 327
Query: 296 FGAGKRVVVILPDGIRNYMTKFVCDQWM 323
F +R+V+ILPD IRNYMTK + WM
Sbjct: 328 FTEQQRIVIILPDNIRNYMTKHLNKTWM 355
>UniRef50_Q4QEG9 Cluster: Cysteine synthase; n=18;
Trypanosomatidae|Rep: Cysteine synthase - Leishmania
major
Length = 359
Score = 290 bits (712), Expect = 4e-77
Identities = 148/326 (45%), Positives = 207/326 (63%), Gaps = 7/326 (2%)
Query: 9 RNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQK 68
RN+I N LE +G+TP +RLNR+P+ +G+ CE+ AKCEF NPGGS+KDRI MVL+A+K
Sbjct: 7 RNQILANALEAVGNTPCIRLNRVPQKHGIRCEVVAKCEFFNPGGSVKDRIGKQMVLDAEK 66
Query: 69 SGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
+G K G+ +E TSGNTGIG+++A A+ G+ I P K S EK +T+ LGAEV++T
Sbjct: 67 NGTLKPGSVIVEATSGNTGIGLSMAAAIRGYHMVITMPKKMSHEKETTLQSLGAEVIRTE 126
Query: 129 AMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIX 187
P++ + + VA RRL ++ + DQY N NP HYE+T +EI VDM+
Sbjct: 127 TSLPYDHPDSLIGVA-RRLRDEKGYVLLDQYTNPSNPGAHYEFTGQEIYDQCGSKVDMVV 185
Query: 188 XXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG-EGPAD--LYFVEGIGGDFVPDV 244
A+K+KE P I+V VDP GS+I E P + +Y VEGIG DFVPDV
Sbjct: 186 ICAGTGGTITGVAKKLKELIPGVIVVGVDPVGSIIADPEHPGEPVMYHVEGIGYDFVPDV 245
Query: 245 LDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVV 304
++ +D+ K D ++F+++ E+ ++EGLL GGSSG+AM + AAK L +R VV
Sbjct: 246 CERKYVDRWVKTRDQESFDLALELHREEGLLVGGSSGSAMAGVLEAAKDLR--PDQRCVV 303
Query: 305 ILPDGIRNYMTKFVCDQWMEAHLFKE 330
++ DGIRNYM KF WM H F++
Sbjct: 304 LMADGIRNYMGKFADVNWMIEHGFRQ 329
>UniRef50_Q23264 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 704
Score = 282 bits (691), Expect = 1e-74
Identities = 147/327 (44%), Positives = 202/327 (61%), Gaps = 7/327 (2%)
Query: 9 RNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQK 68
R + + +L+ IG TPLV+L IPK +G++C ++ KCE++N GGS KDRI+ MV A+K
Sbjct: 375 RPLVLDTVLDAIGKTPLVKLQHIPKAHGVKCNVYVKCEYMNAGGSTKDRIAKRMVEIAEK 434
Query: 69 SGIAKS---GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVV 125
+G G IEPTSGNTGIG++LA+AV G+ C I P K S EK ++ LG+ ++
Sbjct: 435 TGKPGKLVPGVTLIEPTSGNTGIGLSLASAVRGYKCIITMPKKMSKEKSIAMASLGSTII 494
Query: 126 QTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD--V 183
+TP A ++S + VA R E +A+ DQY N NP HYE TAEEI+ + D +
Sbjct: 495 RTPNEAGFDSPHSHIGVALRLKSEIQDAVVLDQYCNPGNPLAHYEETAEEIIYDMGDKHI 554
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG--EGPADLYFVEGIGGDFV 241
D++ ++K+ E+ P +V VDP GS++ G E D Y VEGIG DF+
Sbjct: 555 DLVVLTAGTGGTVTGISRKIHERIPTAKVVGVDPHGSILAGPAETDIDFYEVEGIGYDFL 614
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
P LD S ID K +D ++F M+RE+I+ EG+LCGGSSG A+ A+ K LN A
Sbjct: 615 PGTLDTSAIDYWAKSHDKESFLMARELIRSEGILCGGSSGCAVHYALEECKSLNLPAEAN 674
Query: 302 VVVILPDGIRNYMTKFVCDQWMEAHLF 328
VVV+LPDGIRNY+TKF+ D WM F
Sbjct: 675 VVVLLPDGIRNYITKFLDDDWMNERHF 701
Score = 73.3 bits (172), Expect = 1e-11
Identities = 38/91 (41%), Positives = 60/91 (65%), Gaps = 3/91 (3%)
Query: 236 IGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLN 295
+G D D+L + ++K E D +A++ +R +I EG++ G SSGAA++ AI+ AK+L
Sbjct: 232 MGLDLKNDLLQEYNVEKREVEED-EAYSFTRHLIGTEGIMAGPSSGAAVLEAIKLAKEL- 289
Query: 296 FGAGKRVVVILPDGIRNYMTKFVCDQWMEAH 326
AG +VV+L DGIRNY+ F+ D W+ A+
Sbjct: 290 -PAGSTIVVVLMDGIRNYLRHFLDDDWITAN 319
Score = 59.3 bits (137), Expect = 2e-07
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 2/117 (1%)
Query: 13 YNNILETIG-DTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
YN ILE TPLV L ++ ++ L+ +++ K E++N GS++DR + A++ G+
Sbjct: 19 YNTILEAAQRPTPLVPLKKLKVEHQLQSDIYVKLEYLNIAGSLEDRTADKAFQFAEEIGV 78
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
+ F+ G+ I A AV G TI P D + + LG + V+ P
Sbjct: 79 VRGDEVFV-TAGGSAAISYATVAAVKGIKLTIYAPKGEFDLVDTVLHTLGVKTVELP 134
>UniRef50_A7S1D2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 530
Score = 270 bits (661), Expect = 6e-71
Identities = 143/325 (44%), Positives = 204/325 (62%), Gaps = 14/325 (4%)
Query: 10 NRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
N+I N+L +IG+TP++R+N + K GL+CE+ AKCEF+NP GS+KDRI M+ +A++
Sbjct: 61 NKILPNVLHSIGNTPMIRINNVGKRCGLKCEVVAKCEFMNPVGSLKDRIGVRMIEDAERD 120
Query: 70 GIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
K G IEPTSGNTGI +ALA+AV G+ C IV +K S +K T LG V+ PA
Sbjct: 121 NHIKPGDTLIEPTSGNTGIALALASAVKGYRCVIVMSEKMSSDKADTQKALGGICVRAPA 180
Query: 130 MAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXX 188
A ++S E + +A++ E PN+ +QY+N NP HY+ TAEEIL +DM+
Sbjct: 181 EAKFDSPESTIRLAQQLQKEIPNSYVLNQYRNPSNPLAHYDGTAEEILQQCDGKLDMLVI 240
Query: 189 XXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADL---------YFVEGIGGD 239
A+K++EK P IV VDP GS++ P +L Y VEGIG
Sbjct: 241 GTGTGGTLTGVARKIREKLPHVKIVAVDPYGSVL--AVPEELNKTEPGFKGYNVEGIGKP 298
Query: 240 FVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAG 299
+VP VLD+ ++D+ +K D +AF ++ + K+EGLL GGSSG+ M +A+RAA+ L+
Sbjct: 299 YVPVVLDRDLVDEWQKIGDKEAFYFAKRLSKEEGLLVGGSSGSVMAAAVRAAQDLD--EN 356
Query: 300 KRVVVILPDGIRNYMTKFVCDQWME 324
+R VV+ D IRNYM+KFV D+W+E
Sbjct: 357 QRCVVVFADSIRNYMSKFVSDEWLE 381
>UniRef50_A2QKG7 Cluster: Contig An05c0010, complete genome; n=21;
Ascomycota|Rep: Contig An05c0010, complete genome -
Aspergillus niger
Length = 587
Score = 260 bits (637), Expect = 5e-68
Identities = 139/320 (43%), Positives = 192/320 (60%), Gaps = 7/320 (2%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
+ I + IG+TPLV+LNRIP+ G+E ++AKCE+ N GGS+KDRI+ M+ EA++SG K
Sbjct: 70 DTITQNIGNTPLVKLNRIPRSLGIEATVYAKCEYFNAGGSVKDRIALRMIEEAERSGRIK 129
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPW 133
G IEPTSGNTGIG+AL AV G+ I P+K S EK+S + L A +++TP A +
Sbjct: 130 PGDTLIEPTSGNTGIGLALVAAVKGYKTIITLPEKMSAEKVSVLRALNATIIRTPNEAAF 189
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXX 192
+S E + VAKR E PNA DQY N NP H TAEEI + +
Sbjct: 190 DSPESHIGVAKRLEKELPNAHILDQYGNVNNPLAHELGTAEEIWVQTEGRISAVVAGAGT 249
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF------GEGPADLYFVEGIGGDFVPDVLD 246
++ +K+ P ++ DP GS++ E + Y VEGIG DF+P+VLD
Sbjct: 250 GGTITGISRGLKKHNPDIQVIAADPHGSILALPAALNDEHLNEPYKVEGIGYDFIPEVLD 309
Query: 247 KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVIL 306
+ +DK K D ++F SR +I +EGLL GGSSG+A+ + +AAK F VVV+L
Sbjct: 310 RQAVDKWYKTADKESFQYSRRLIAEEGLLVGGSSGSAISALAQAAKDNRFKKDDVVVVVL 369
Query: 307 PDGIRNYMTKFVCDQWMEAH 326
PD IR+Y+TKF D W+ A+
Sbjct: 370 PDSIRSYLTKFADDDWLAAN 389
>UniRef50_Q1DVL4 Cluster: Cysteine synthase; n=3; Fungi/Metazoa
group|Rep: Cysteine synthase - Coccidioides immitis
Length = 339
Score = 246 bits (601), Expect = 1e-63
Identities = 132/319 (41%), Positives = 191/319 (59%), Gaps = 9/319 (2%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
+++ + IG TPLVRLNR+P G++ +++AK E+ N GGS+KDRI+ M+ +A++ G+ K
Sbjct: 12 DSVADYIGGTPLVRLNRVPAALGIKAQVYAKLEYFNAGGSVKDRIAKHMIEQAERDGVIK 71
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPW 133
G IE +SGNTGI +AL A+ G+ C I +K S EK + LGA VV+TPA P
Sbjct: 72 PGDTLIEASSGNTGIAIALMAAIKGYKCIITLSEKMSLEKEQILHALGARVVRTPAGVPI 131
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXXX 192
+S + +SVAKR E P + DQY N NP H TAEEI VD +
Sbjct: 132 DSPDSIISVAKRLRNEIPRSFILDQYTNPANPAAHEFGTAEEIWHQTQGKVDAVISGAGT 191
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLI-----FGEGPADLYFVEGIGGDFVPDVLDK 247
A+ +K+ P +V VDP GS++ E + Y VEGIG DF+PDVLD+
Sbjct: 192 GGTVTGIAKGMKKHNPDVFLVGVDPVGSILAIPERLNETKGE-YKVEGIGYDFLPDVLDQ 250
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIR-AAKKLNFG-AGKRVVVI 305
+ D K D D+F ++R ++++EGLLCGGS+GA + + ++ ++ F K +V+I
Sbjct: 251 TAPDLWVKTTDKDSFKLARRLVREEGLLCGGSAGATVAALVQFMEQRPEFNKEEKLIVLI 310
Query: 306 LPDGIRNYMTKFVCDQWME 324
L DG+RNY+TKF D WM+
Sbjct: 311 LADGLRNYLTKFADDNWMK 329
>UniRef50_P32582 Cluster: Cystathionine beta-synthase; n=10;
Saccharomycetales|Rep: Cystathionine beta-synthase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 507
Score = 245 bits (600), Expect = 2e-63
Identities = 132/324 (40%), Positives = 196/324 (60%), Gaps = 13/324 (4%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG-IA 72
+N+++ +G+TPL+ L ++PK G++ +++AK E NPGGSIKDRI+ +MV EA+ SG I
Sbjct: 12 HNVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIH 71
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
S + IEPTSGNTGIG+AL A+ G+ I P+K S+EK+S + LGAE+++TP A
Sbjct: 72 PSRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAA 131
Query: 133 WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDM------I 186
W+S E + VAK+ E P A+ DQY N +NP HY T EI + D+++ +
Sbjct: 132 WDSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAV 191
Query: 187 XXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF---GEGPADL--YFVEGIGGDFV 241
++ +KE+ K IV DP GS++ D+ Y VEGIG DFV
Sbjct: 192 VAGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFV 251
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAK-KLNFGAGK 300
P VLD+ +ID K +D +F +R++I EG+L GGSSG+A + ++ +
Sbjct: 252 PQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDHPELTEDD 311
Query: 301 RVVVILPDGIRNYMTKFVCDQWME 324
+V I PD IR+Y+TKFV D+W++
Sbjct: 312 VIVAIFPDSIRSYLTKFVDDEWLK 335
>UniRef50_Q6MGX3 Cluster: Cysteine synthase; n=2; Bacteria|Rep:
Cysteine synthase - Bdellovibrio bacteriovorus
Length = 348
Score = 239 bits (586), Expect = 8e-62
Identities = 133/347 (38%), Positives = 200/347 (57%), Gaps = 13/347 (3%)
Query: 10 NRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
+ IY++ILETIG+TP+VRL + K G + + FAK E+ NPGGSIKDR++ M+ EA+K
Sbjct: 2 SHIYDSILETIGNTPIVRLKNVTK--GSKHQFFAKIEYFNPGGSIKDRVAVAMIEEAEKR 59
Query: 70 GIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
G K+G +E TSGNTG+G+ALA AV G+ C V P+K S+EK + + GA+VV TP
Sbjct: 60 GDLKAGGTIVEATSGNTGVGLALAAAVKGYKCIFVMPEKMSEEKRAILRAYGAKVVITPM 119
Query: 130 MAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXX 188
+ P H+ SV+++ E P A +QY N NP+ HY+ T EI + VD++
Sbjct: 120 VDPEHPLSHY-SVSQKIAKETPGAFLTNQYHNPDNPQRHYQTTGPEIWKQMDGKVDVVVG 178
Query: 189 XXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG-------EGPADLYFVEGIGGDFV 241
A+ +KE P + DP GS+++ P Y VEG+G D +
Sbjct: 179 GAGTGGTLSGVAKYLKEMNPNIKAICADPIGSILYDLYYHKKIVDPPGSYKVEGVGEDML 238
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
PD + ++ D E+ +D +AF M+R ++ +EGLL G SS A++ A++AA+K+
Sbjct: 239 PDNVHLNIYDGFERVSDPEAFTMTRRLVAEEGLLVGPSSALALVGAMKAAEKIE--KPSN 296
Query: 302 VVVILPDGIRNYMTKFVCDQWMEAHLFKEPPEREFLFFKGVLTKDSL 348
+VV+ PD R Y++K D WM + +P E + +F + V D L
Sbjct: 297 IVVVFPDSGRAYLSKAFNDTWMIENALLKPEEAKNVFNRVVNAADFL 343
>UniRef50_A7HH29 Cluster: Pyridoxal-5'-phosphate-dependent protein
beta subunit; n=7; Bacteria|Rep:
Pyridoxal-5'-phosphate-dependent protein beta subunit -
Anaeromyxobacter sp. Fw109-5
Length = 459
Score = 230 bits (563), Expect = 5e-59
Identities = 128/325 (39%), Positives = 188/325 (57%), Gaps = 15/325 (4%)
Query: 13 YNNILETIGDTPLVRLNRI--PKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
++++L IG TPLVRL ++ P D + K E++NPGGSIKDR++ ++ +A+K+G
Sbjct: 4 HDDVLSAIGRTPLVRLRKLVGPDD----ATVLVKLEYLNPGGSIKDRMALHIIEKAEKAG 59
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
+ + G+ +E TSGNTG+G+A+A AV G+ C PDK S EK T+ GA+VV TP
Sbjct: 60 LLRKGSTIVENTSGNTGVGIAIAAAVKGYRCIFTMPDKMSKEKQDTLKAFGAQVVVTPTN 119
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALV-PDVDMIXXX 189
P +S + + SVAKR E PN+ +QY N N HY TA EI +D
Sbjct: 120 VPADSPDSYYSVAKRIAAETPNSFYLNQYHNVDNIEAHYRSTAPEIWEQTGGQLDAFVAG 179
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSL---IFGEGPAD---LYFVEGIGGDFVPD 243
+ KE+ P+ + V DP GS+ +F G +Y VEGIG D +
Sbjct: 180 LGTGGTMSGCGKYFKERNPRILNVGADPIGSVYHSMFKTGKLSQPHVYKVEGIGEDMMCG 239
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVV 303
+D SV+D V + ND +F M+R + ++EG+ GGSSG+A+ A++ A++L G GK +V
Sbjct: 240 AMDLSVLDDVRQVNDQQSFTMTRRLAREEGIFAGGSSGSAVHVAVQLAREL--GKGKTIV 297
Query: 304 VILPDGIRNYMTKFVCDQWMEAHLF 328
V LPDG R Y++K D+WM + F
Sbjct: 298 VPLPDGGRAYISKLYSDEWMRDNGF 322
>UniRef50_Q129P7 Cluster: Cysteine synthase; n=22; cellular
organisms|Rep: Cysteine synthase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 332
Score = 219 bits (535), Expect = 1e-55
Identities = 124/321 (38%), Positives = 177/321 (55%), Gaps = 11/321 (3%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
Y +IL+ IG TPLVRLN++ + L C ++AK EF++PGGS+KDRI M+ +A++ G
Sbjct: 3 YESILDAIGHTPLVRLNQLTRH--LSCAVYAKLEFLSPGGSVKDRIGMYMIQQAERRGEI 60
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
G +E TSGNTG+G+AL A G+ DK S EK+ + +GAEV+ P P
Sbjct: 61 GPGATIVECTSGNTGMGLALFAAGRGYKTVFTIADKQSKEKVDMLRAMGAEVIVCPTDVP 120
Query: 133 WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXX 191
+ ++ A+R + P A C+QY N N HY T EI V
Sbjct: 121 PDDPRGYIQAAQRLARDIPGAFLCNQYDNPDNTLAHYASTGPEIWNDTGGMVTHFVCGMG 180
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSL---IFGEG---PADLYFVEGIGGDFVPDVL 245
+ +KE+ ++ VDPQGS+ +F G +Y +EGIG DF+P L
Sbjct: 181 TCGTISGAGRYLKEQNAMVRVIGVDPQGSIFHELFHRGVTVQPHVYRLEGIGEDFIPKAL 240
Query: 246 DKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVI 305
D VID V + +D +F M+R + + EG+ GGSSGAAM++A++ A+KL G +VV+
Sbjct: 241 DWHVIDDVIQVSDQGSFLMARRLARDEGIFAGGSSGAAMLAALQVAEKL--GPNDLMVVL 298
Query: 306 LPDGIRNYMTKFVCDQWMEAH 326
LPDG R Y+ K D WM H
Sbjct: 299 LPDGGRQYLGKLYNDDWMREH 319
>UniRef50_Q1INP9 Cluster: Cysteine synthases; n=1; Acidobacteria
bacterium Ellin345|Rep: Cysteine synthases -
Acidobacteria bacterium (strain Ellin345)
Length = 315
Score = 217 bits (530), Expect = 5e-55
Identities = 117/316 (37%), Positives = 179/316 (56%), Gaps = 11/316 (3%)
Query: 3 NSRSFTRNRIYNNILETIGDTPLVRLNR-IPKDYGLECEMFAKCEFVNPGGSIKDRISYT 61
N+ + R+ +I E +G TP++ L + +P + +++ K EF+NPGGSIKDR +
Sbjct: 2 NTSEMSTLRVAEDISELVGQTPMLHLRKMVPPEIA---DIYVKLEFLNPGGSIKDRAALG 58
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
M+L A+K G+ K G +E T+GNTG+G+AL G+ + P K S EK+ + LG
Sbjct: 59 MILRAEKEGVLKPGATILEATAGNTGVGLALIGVSRGYKVVLAVPQKFSKEKVMLMEALG 118
Query: 122 AEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALV 180
A+V +TP E E + + K+ L E PN+ Q++N NP HYE T E+ +
Sbjct: 119 AQVYRTPDA---EGMEGAIRLVKKFLTEIPNSWLAGQFENQANPDFHYETTGRELWEQMG 175
Query: 181 PDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDF 240
+D I A+ +KE+ P+ + V V+ Q S ++G G + + VEGIG F
Sbjct: 176 GKIDAIALGAGTAGTFTGVARYLKERSPQTLCVLVESQAS-VYGGGKSGPHAVEGIGASF 234
Query: 241 VPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGK 300
+P D+SV D+V D DAF +++ KEG+L G SSGAA+ +++ AK+L G GK
Sbjct: 235 IPATFDRSVCDEVIAVKDVDAFRTIKDLAAKEGVLAGSSSGAAVFASLELAKRL--GPGK 292
Query: 301 RVVVILPDGIRNYMTK 316
RVV I+PD Y++K
Sbjct: 293 RVVTIIPDSAERYLSK 308
>UniRef50_A5N6W4 Cluster: Cysteine synthase; n=1; Clostridium
kluyveri DSM 555|Rep: Cysteine synthase - Clostridium
kluyveri DSM 555
Length = 303
Score = 216 bits (527), Expect = 1e-54
Identities = 114/305 (37%), Positives = 178/305 (58%), Gaps = 10/305 (3%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
YN+I E +G+TP+++LN + + E +FAK E NPGGS+KDRI M+ A+K G+
Sbjct: 4 YNDIKEMVGNTPILKLNNL--NVKREIGIFAKLESFNPGGSVKDRIGLYMIDSAEKKGLL 61
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
G +E T+GNTG+G+AL G+ V P+K S EK + LGAE++ TP
Sbjct: 62 NKGYTIVEATAGNTGLGIALGALNRGYKVIFVVPEKFSQEKQILMKALGAEIINTPKE-- 119
Query: 133 WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI-LALVPDVDMIXXXXX 191
E + ++ L + PN+IS Q++N+ NP+ HY T EI + + ++D +
Sbjct: 120 -EGMLGAIEKSQELLRDIPNSISLKQFENEDNPKAHYLTTGPEIYMDMEGNIDYLVAGAG 178
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVID 251
AQ +KEK + VDP+GS + G G Y +EGIG +F+P+ +D ++D
Sbjct: 179 SGGTFTGVAQYLKEKNKNIKSILVDPEGSTM-GGGTEGCYGIEGIGNNFIPETMDMGLVD 237
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
K+ K ND +AF+M R++ +KEGL+ G SSGAA++ A++ A+ ++ G +VV+ PD
Sbjct: 238 KIIKVNDEEAFHMVRKLAEKEGLIVGSSSGAALVGALKLAQSIDKG---NIVVVFPDRGD 294
Query: 312 NYMTK 316
Y +K
Sbjct: 295 RYFSK 299
>UniRef50_Q9CB65 Cluster: Cystathionine; n=13; Actinomycetales|Rep:
Cystathionine - Mycobacterium leprae
Length = 464
Score = 212 bits (517), Expect = 2e-53
Identities = 124/321 (38%), Positives = 176/321 (54%), Gaps = 9/321 (2%)
Query: 11 RIYNNILETIGDTPLVRLNRI-PKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
RI +I + IG TPLVRLN + P G+ + AK E+ N GGS KDRI+ M+ A+ S
Sbjct: 2 RIAQHISDLIGGTPLVRLNSVVPAGTGV---VAAKVEYFNSGGSSKDRIAAKMIDAAEAS 58
Query: 70 GIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
G K G +EPTSGNTG+G+AL G+ C V PDK S++K + + GAEVV P
Sbjct: 59 GQLKPGGTIVEPTSGNTGVGLALVAQHRGYKCVFVCPDKVSEDKRNVLLAYGAEVVVCPT 118
Query: 130 MAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXX 188
P + + + SV+ R + + A DQY N P +HYE T EI A V
Sbjct: 119 AVPPDDPDSYYSVSDRLVAKIDGAWKPDQYANPAGPASHYETTGPEIWADTDGRVTHFVA 178
Query: 189 XXXXXXXXXXXAQKVKEKCPKCI-IVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDK 247
+ +KE + I+ DP+GS ++ G Y VEG+G DF P D
Sbjct: 179 GIGTGGTITGVGRYLKEVSGGLVRIIGADPEGS-VYSGGTGRPYLVEGVGEDFWPAAYDP 237
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
V D++ +D D+FNM+R + ++E +L GGS G A+++A++ A++ G VVV+LP
Sbjct: 238 MVPDQIIAVSDSDSFNMTRRLAREEAMLVGGSCGMAVVAALQVAEEA--GPAALVVVLLP 295
Query: 308 DGIRNYMTKFVCDQWMEAHLF 328
DG R YM+K D WM ++ F
Sbjct: 296 DGGRGYMSKIFNDAWMSSYGF 316
>UniRef50_Q7D8W0 Cluster: Cysteine synthase/cystathionine
beta-synthase family protein; n=27;
Actinobacteridae|Rep: Cysteine synthase/cystathionine
beta-synthase family protein - Mycobacterium
tuberculosis
Length = 464
Score = 211 bits (516), Expect = 2e-53
Identities = 124/320 (38%), Positives = 174/320 (54%), Gaps = 7/320 (2%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
RI +I E IG TPLVRLN + D + AK E++NPGGS KDRI+ M+ A+ SG
Sbjct: 2 RIAQHISELIGGTPLVRLNSVVPDGA--GTVAAKVEYLNPGGSSKDRIAVKMIEAAEASG 59
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
K G +EPTSGNTG+G+AL G+ C V PDK S++K + + GAEVV P
Sbjct: 60 QLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTA 119
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA-LVPDVDMIXXX 189
P + SV+ R + + A DQY N P +HY T EI A V
Sbjct: 120 VPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAG 179
Query: 190 XXXXXXXXXXAQKVKE-KCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKS 248
+ +KE + IV DP+GS ++ G Y VEG+G DF P D S
Sbjct: 180 IGTGGTITGAGRYLKEVSGGRVRIVGADPEGS-VYSGGAGRPYLVEGVGEDFWPAAYDPS 238
Query: 249 VIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPD 308
V D++ +D D+F+M+R + ++E +L GGS G A+++A++ A++ G +VV+LPD
Sbjct: 239 VPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEA--GPDALIVVLLPD 296
Query: 309 GIRNYMTKFVCDQWMEAHLF 328
G R YM+K D WM ++ F
Sbjct: 297 GGRGYMSKIFNDAWMSSYGF 316
>UniRef50_Q8G564 Cluster: Cystathionine beta-synthase; n=2;
Bifidobacterium longum|Rep: Cystathionine beta-synthase
- Bifidobacterium longum
Length = 408
Score = 206 bits (504), Expect = 7e-52
Identities = 116/327 (35%), Positives = 175/327 (53%), Gaps = 4/327 (1%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I+N++ E IG+TPLV+LN IP+ G++ + K E+ NPGGS KDRI+ ++ A++SG
Sbjct: 56 IHNSLAELIGNTPLVKLNHIPQAAGVKATIAVKVEYFNPGGSSKDRIAERIIDAAEQSGQ 115
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K G +EPTSGNTG+G+AL G+ PDK S+ K + + GAEV+ TP A
Sbjct: 116 LKPGGVIVEPTSGNTGVGLALVAQQRGYRTIFTLPDKVSESKRAVLRAYGAEVIVTPTDA 175
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIXXXX 190
+ + VA+R P +QY N P +HY T EI A V
Sbjct: 176 GPDDPRSYYQVAERLANTIPGGFRPNQYDNPNGPLSHYYTTGPEIWEATDHKVTHFVAGI 235
Query: 191 XXXXXXXXXAQKVKEKCPKCI-IVTVDPQGSLIFGEGPADL--YFVEGIGGDFVPDVLDK 247
+ +KE + ++ DP+GS+ ++ Y +EG+G DF P D+
Sbjct: 236 GTGGTISGTGKYLKEASNGAVKVIGSDPEGSIYSASSRDEVHQYDIEGVGEDFYPKAFDR 295
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
++ D + + +D +AF M+R + +E LL GGSSG A+ SAI+ A + + VVV+ P
Sbjct: 296 NITDDIVRVSDAEAFEMTRRLAGEEALLVGGSSGMAVASAIKYALANDLDENQIVVVLAP 355
Query: 308 DGIRNYMTKFVCDQWMEAHLFKEPPER 334
D R+Y+ K D WM A+ + + ER
Sbjct: 356 DSGRSYLEKIFNDDWMRANGYGDIVER 382
>UniRef50_Q3B030 Cluster: Cysteine synthase; n=22; Bacteria|Rep:
Cysteine synthase - Synechococcus sp. (strain CC9902)
Length = 322
Score = 201 bits (491), Expect = 3e-50
Identities = 114/303 (37%), Positives = 171/303 (56%), Gaps = 6/303 (1%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG-IAK 73
+I IG TPLVRLNR+P+ G + E+ AK E NP S+KDRI+ MVLEA+++G IA
Sbjct: 6 DITALIGGTPLVRLNRLPQACGSQAEVLAKLESFNPSASVKDRIASAMVLEAEQAGTIAP 65
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPW 133
T +EPTSGNTGI +A+ A G+ + P+ S E+ + + GAE+ T
Sbjct: 66 GRTVLVEPTSGNTGIALAMVAAARGYRLILTMPESMSTERRAMLRAYGAELQLTDGS--- 122
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDV-DMIXXXXXX 192
E + +++AK + E P A Q+ N NP H TAEEI V D++
Sbjct: 123 EGMKGAIALAKELVAEIPEAYLLQQFDNSANPAVHERTTAEEIWTDCDGVLDVLVAGVGT 182
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDK 252
A+ +K++ P+ +V V+P+ S + G + ++GIG F+P+VLD +ID
Sbjct: 183 GGTITGCARVLKQRNPQLQVVAVEPEASPVLSGGSPGAHRIQGIGAGFIPEVLDLDLIDL 242
Query: 253 VEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRN 312
+ +D DA M R + ++EGLLCG SSGAA+ +A+R A++ A KR+VV+L
Sbjct: 243 IVAVSDDDAMEMGRRLAREEGLLCGISSGAAIAAALRLAQQPGM-ANKRMVVMLASYGER 301
Query: 313 YMT 315
Y++
Sbjct: 302 YLS 304
>UniRef50_A1ZUX3 Cluster: Cysteine synthase; n=1; Microscilla marina
ATCC 23134|Rep: Cysteine synthase - Microscilla marina
ATCC 23134
Length = 347
Score = 198 bits (484), Expect = 2e-49
Identities = 117/322 (36%), Positives = 175/322 (54%), Gaps = 13/322 (4%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
Y N+LETIG+TPL++LN++ +D ++ + AK E NPG S+KDR++ MV +A+ G
Sbjct: 17 YKNVLETIGNTPLIKLNQVVED--IDATVLAKVETTNPGNSVKDRMALKMVEDAEARGEL 74
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
K G IE TSGNTG+G+A+A V G+ C K S EK+ + LGA V+ P+
Sbjct: 75 KPGGVIIECTSGNTGMGLAIAAVVKGYRCIFTATSKQSKEKIDLLRALGATVIICPSEVH 134
Query: 133 WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXX 191
+ E + SVA++ + PN+ C+QY N N HY+ T EI +
Sbjct: 135 PDHPESYYSVAQQLYHKTPNSFWCNQYDNPSNVLAHYQSTGPEIWQQTQGQITHFIVGIG 194
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSL---IFGEGPADL-----YFVEGIGGDFVPD 243
+ +KE+ P+ I V+P GS+ + G D+ Y EGIG D VP
Sbjct: 195 TGGTISGVGRYLKEQNPQVKIWGVEPHGSVLKSVHETGKVDISQSHKYATEGIGQDMVPV 254
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVV 303
+D +ID +EK + DA M+R I++KE +L G S+GAA+ ++ K+L + VV
Sbjct: 255 NVDFEIIDHIEKVSCKDAALMTRAILQKEAILVGNSAGAAVAGLLQLKKQLK--SSDVVV 312
Query: 304 VILPDGIRNYMTKFVCDQWMEA 325
V+ D Y+ K + D+WMEA
Sbjct: 313 VLFHDHASRYIGKILNDEWMEA 334
>UniRef50_A7HGE3 Cluster: Cysteine synthase precursor; n=9;
Bacteria|Rep: Cysteine synthase precursor -
Anaeromyxobacter sp. Fw109-5
Length = 324
Score = 197 bits (481), Expect = 4e-49
Identities = 114/304 (37%), Positives = 163/304 (53%), Gaps = 12/304 (3%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSG 75
IL+ +G TP+VRL+R+ E+ AK E NPGGS+KDRI+ M+ A++ G G
Sbjct: 18 ILDAVGGTPIVRLSRVVPPEA--AEVLAKLESFNPGGSVKDRIAVAMIEAAEREGRLAPG 75
Query: 76 TRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWES 135
R +EPTSGNTG+G+ALA AV G+ T+V PD S E + GA +V TPA E
Sbjct: 76 ARVVEPTSGNTGLGLALACAVKGYRLTLVMPDSTSLEHRQALEAYGAALVLTPA----ED 131
Query: 136 SEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL----ALVPDVDMIXXXXX 191
L A+ Q++N NP H + TA E++ AL +D
Sbjct: 132 GMTPAVARADELARREGALLLQQFENPANPAAHRQGTARELVAAFDALGAPMDAFVAGVG 191
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVID 251
A ++++ P +IV V+P + GPA ++G+G FVP VLD D
Sbjct: 192 TGGTITGVADVLRQERPGTLIVAVEPDACAVLSGGPAGPTRIQGLGAGFVPAVLDARAYD 251
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
+VE+ D +A+ M + + EGLL G SSGAA+++A+R A++L G G+RV ILPD
Sbjct: 252 RVERVADEEAWAMKLRLARDEGLLVGTSSGAAVVAALRVAREL--GPGRRVATILPDSGE 309
Query: 312 NYMT 315
Y +
Sbjct: 310 RYFS 313
>UniRef50_A7GZ74 Cluster: Cysteine synthase A; n=1; Campylobacter
curvus 525.92|Rep: Cysteine synthase A - Campylobacter
curvus 525.92
Length = 321
Score = 194 bits (474), Expect = 3e-48
Identities = 107/305 (35%), Positives = 164/305 (53%), Gaps = 12/305 (3%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
IY NI +TIG TP+V+L K E E++AK EF NPGGS+KDRI+ M+ + Q G
Sbjct: 22 IYQNIAQTIGKTPVVKL----KTGADEAEIYAKLEFFNPGGSVKDRIALNMIEKMQADGT 77
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K G +EPTSGNTGIG+A+ A G+ + P+ S E+ ++ GA + TPA
Sbjct: 78 LKKGDTIVEPTSGNTGIGIAMVAASLGYKVVLCMPESMSIERRKIVAAYGARLELTPAAN 137
Query: 132 PWESSEHFLSVAK-RRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXX 190
+ ++AK L PN + Q++N NP+ H T EE+ A +D
Sbjct: 138 GMKG-----AIAKAHELASQPNHVMLSQFENKYNPQAHELTTGEEVAADFTSLDAFVAGV 192
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVI 250
A+ +K K + V+P+ S + G + ++G+ F+P +D S++
Sbjct: 193 GTGGTISGVAKALKAKGYATKFIAVEPEASPVLSGGNPGPHKIQGLAPGFIPATMDMSIV 252
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
D +EK ++ DA + SR + K +G++ G S GAA ++A R AK L GAGK+V+ + PD
Sbjct: 253 DGIEKISNEDAMSGSRALAKSDGIMLGISGGAAYVAAKRVAKAL--GAGKKVLFVAPDNG 310
Query: 311 RNYMT 315
Y++
Sbjct: 311 ERYLS 315
>UniRef50_A6GXZ8 Cluster: Cysteine synthase/cystathionine
beta-synthase family protein; n=1; Flavobacterium
psychrophilum JIP02/86|Rep: Cysteine
synthase/cystathionine beta-synthase family protein -
Flavobacterium psychrophilum (strain JIP02/86 / ATCC
49511)
Length = 355
Score = 194 bits (472), Expect = 5e-48
Identities = 114/334 (34%), Positives = 175/334 (52%), Gaps = 11/334 (3%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
+ YNN+LE IG+TPL+++++I + GL+ +AK E NPG S KDRI+ ++ EA+K G
Sbjct: 15 KAYNNVLELIGNTPLIKIDKITE--GLKGNFYAKVEAFNPGHSTKDRIALYIIEEAEKQG 72
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
I K G IE TSGNTG +A+ + + G+ C K+S +K+ + +GA+V PA
Sbjct: 73 ILKPGDTIIETTSGNTGFSLAMVSIIKGYDCIFAISSKSSADKIDMLRSMGAKVYVCPAH 132
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALV-PDVDMIXXX 189
+ + SVAKR E ++ +QY N +N HY+ T EI + +
Sbjct: 133 VSADDERSYYSVAKRLHEEIKGSVYINQYFNHLNIEAHYKSTGPEIWEQTNGKITHLIAC 192
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLI--------FGEGPADLYFVEGIGGDFV 241
A+ +KEK P I+ VD GS+I F + Y +EG+G + +
Sbjct: 193 TGTGGTISGIAKFLKEKNPNIRILGVDAYGSVIKKYHETKEFDKDEIYPYRIEGLGKNLI 252
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
P LD +IDK K D ++ +M+R I K EGL G +SGA + + + A++ F
Sbjct: 253 PSALDFDLIDKFVKVTDEESAHMTRNIAKVEGLFVGYTSGAVVQAIKQYAEEGEFDEKSN 312
Query: 302 VVVILPDGIRNYMTKFVCDQWMEAHLFKEPPERE 335
++ I PD YM+K ++WMEA F + E
Sbjct: 313 IIAIFPDHGSRYMSKVFNEEWMEAQGFFDSVNEE 346
>UniRef50_Q4S0J1 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF14781, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 534
Score = 193 bits (471), Expect = 7e-48
Identities = 95/198 (47%), Positives = 126/198 (63%), Gaps = 1/198 (0%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I NIL TIG TPLVRLN+IPK++G++C++ KCEF + GGSIKDRI+ MV +A+ + +
Sbjct: 34 ILPNILGTIGHTPLVRLNKIPKEFGIKCDILVKCEFFSAGGSIKDRIALRMVEDAETARL 93
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K G IEPTSGNTGIG+AL +V G+ C I PD+ S EK+ + LGAE+V TP+
Sbjct: 94 LKPGDTIIEPTSGNTGIGLALVASVKGYRCVITMPDRMSKEKVDVLKALGAEIVHTPSSV 153
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXX 190
P++S E + A R + PN+ DQY+N NP HY+ TAEEIL +DM
Sbjct: 154 PFDSPESHVGTAWRLKNKIPNSYILDQYRNASNPLAHYDATAEEILEQCDGKLDMFVAGI 213
Query: 191 XXXXXXXXXAQKVKEKCP 208
A+K+KEKCP
Sbjct: 214 GTGGTLTGVARKLKEKCP 231
Score = 114 bits (274), Expect = 5e-24
Identities = 59/106 (55%), Positives = 75/106 (70%), Gaps = 4/106 (3%)
Query: 212 IVTVDPQGSLIFGEGPA--DLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREII 269
IV VDP+GSL+ Y VEGIG DFVP VLDKS++D K ND + F MSR +I
Sbjct: 264 IVAVDPEGSLLIQSNNQCKTSYEVEGIGYDFVPTVLDKSLVDHFYKVNDKETFRMSRRLI 323
Query: 270 KKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
+ EGLLCGGSSG+AM +A++AA++L G+R VVIL D +RNYM+
Sbjct: 324 RDEGLLCGGSSGSAMAAAVKAARQLK--EGQRCVVILADSVRNYMS 367
>UniRef50_Q1W0E5 Cluster: Cystathionine beta-synthase; n=12;
Bacteroidetes|Rep: Cystathionine beta-synthase -
Psychroflexus torquis ATCC 700755
Length = 354
Score = 193 bits (471), Expect = 7e-48
Identities = 114/333 (34%), Positives = 172/333 (51%), Gaps = 11/333 (3%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
+++N+L +G TPL+RLN I + + + E AK E NPG S KDRI++ ++ +A+K+G
Sbjct: 7 VHDNLLSMVGCTPLIRLNNITQHF--KGEFLAKYEAQNPGLSSKDRIAHYIIEKAEKNGD 64
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K G IE TSGNTG +A+ A+ G+ C + K+S +K+S + +GA+V P+
Sbjct: 65 IKPGDTIIETTSGNTGFSIAMIAAIKGYKCILAVSSKSSKDKISLLKTMGADVTVCPSNV 124
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXX 190
E + VAKR E P +I +QY ND+N HY T EI + +
Sbjct: 125 APEDPRSYYEVAKRIYNETPGSIYINQYFNDLNIDAHYLTTGPEIWEQTQGKITHLVACS 184
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLI--------FGEGPADLYFVEGIGGDFVP 242
A+ +KE+ P I+ +D GS++ F + Y +EG+G + +P
Sbjct: 185 GTGGTISGTARYLKEQNPDIKILGIDAFGSVLQKYHETGKFDKSEIYPYKIEGLGKNLIP 244
Query: 243 DVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRV 302
D VIDK K D D+ M+R+I K EG+ G +SGA M + A + F + +V
Sbjct: 245 SATDFDVIDKFTKVTDEDSAYMARDIAKTEGMFVGYTSGAVMQGIKQLAAENEFNSESKV 304
Query: 303 VVILPDGIRNYMTKFVCDQWMEAHLFKEPPERE 335
V I PD YM+K D WM++ F P E
Sbjct: 305 VAIFPDHGSRYMSKVFSDDWMKSQGFTNYPGLE 337
>UniRef50_Q15UN6 Cluster: Cysteine synthase; n=1; Pseudoalteromonas
atlantica T6c|Rep: Cysteine synthase - Pseudoalteromonas
atlantica (strain T6c / BAA-1087)
Length = 343
Score = 193 bits (471), Expect = 7e-48
Identities = 113/315 (35%), Positives = 169/315 (53%), Gaps = 5/315 (1%)
Query: 2 SNSRSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYT 61
S S +FTR RIY +I +TIG+TPLVRL+R+ K Y E+ AK E+ NP GSIKDR +
Sbjct: 26 SPSATFTRGRIYEDITQTIGNTPLVRLSRLGKKYSTLGEILAKVEYFNPAGSIKDRPALA 85
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
M+ S T+ IE TSGN G+ A A+ G TIV P+ S E+ I G
Sbjct: 86 MINALMLSDSFDENTQIIEATSGNNGVACAWICAMKGIPLTIVIPEHMSIERQKLIKHYG 145
Query: 122 AEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA-LV 180
A+V+ TP ++ + AK + E +A+ DQ+ N NP H+ TA+EI
Sbjct: 146 AKVITTPKDL---GTKGAIDKAKALVGETRSAVMLDQFGNQANPDMHFNSTAQEIWRDTN 202
Query: 181 PDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDF 240
+VD++ A+ +K + PK I+ V+P + EG ++ ++G+
Sbjct: 203 GEVDVLIAGVGTGGTITGIAKALKIRNPKIKIIAVEPASCPVLSEGRGGVHKIQGLSSGH 262
Query: 241 VPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGK 300
VPDVLD S++D++ ++ DA +RE+ + E L G SSGAA +A++ A++ GK
Sbjct: 263 VPDVLDVSLLDEIMTVSNEDAIAYARELARVESLPVGISSGAAAYAAVQVAQRAEL-TGK 321
Query: 301 RVVVILPDGIRNYMT 315
+V IL D Y +
Sbjct: 322 NIVTILADTAERYFS 336
>UniRef50_Q7MYV0 Cluster: Cysteine synthase; n=1; Photorhabdus
luminescens subsp. laumondii|Rep: Cysteine synthase -
Photorhabdus luminescens subsp. laumondii
Length = 342
Score = 190 bits (462), Expect = 8e-47
Identities = 114/318 (35%), Positives = 169/318 (53%), Gaps = 8/318 (2%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
NIL+TIG+TP+V LN Y +F K E +NPGGSIKDRI+ M+ A+ G +
Sbjct: 6 NILQTIGNTPVVMLNG---RYTKGINVFLKMENINPGGSIKDRIAVAMLERAEAQGELRP 62
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM-APW 133
G IEP+SGNT IG+A+A AV G+ V K I GAE++ P A
Sbjct: 63 GMVVIEPSSGNTAIGLAMACAVKGYRFIAVLDRMVPAAKRDKIKAFGAEIIFLPEFEAGK 122
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALV-PDVDMIXXXXXX 192
++ ++ + + K + PNA S Q++N VNP HY T E+ + ++
Sbjct: 123 DTVKYRIDLTKEIIKVYPNAFSPMQFENQVNPDEHYRSTGRELYEIFGNNLTACFATAGS 182
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDK 252
++ +KEK P+ I V+P GS+IFG P Y V+G G F+P +LD++ ID
Sbjct: 183 CGTLTGISRYLKEKDPQVRIYGVEPVGSIIFGGEPGK-YLVQGAGLAFIPSILDRTNIDI 241
Query: 253 VEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRN 312
K D DAF ++R++ + EG+L GG+ G A+ +A+ +F G +VVI+PD
Sbjct: 242 TLKVADIDAFRVARKLARNEGILIGGTGGCAVSAALNRLD--DFKPGDNIVVIIPDSGER 299
Query: 313 YMTKFVCDQWMEAHLFKE 330
Y+ D W+ + F E
Sbjct: 300 YIDTIYNDAWLFENNFSE 317
>UniRef50_A3DLF6 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Staphylothermus marinus F1|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 /
F1)
Length = 338
Score = 188 bits (458), Expect = 3e-46
Identities = 108/315 (34%), Positives = 167/315 (53%), Gaps = 12/315 (3%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
R+ NN++E IG TP++RL RI KD ++ E++AK EF+NP GS+KDR++Y M+ +A G
Sbjct: 4 RVCNNVIECIGKTPIIRLQRIEKDQNVDFEIWAKAEFMNPTGSVKDRMAYYMIKKAMDKG 63
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
K G + PT+GNTGI + + G IV P++ S E+ + L GA+ + TP
Sbjct: 64 ELKPGMTIVVPTTGNTGISFSALGSYFGLKVLIVIPEEMSAERFMLMRLFGADFLFTPGG 123
Query: 131 APWESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXX 189
+ L AK+ E+P+ DQ+ ++ N + HYE T +EIL + D
Sbjct: 124 E--SDAGTALETAKKLAEENPDKYYFFDQWSDEANVQAHYETTGKEILDQIGCPDAFVAQ 181
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG-------EGPADLYFVEGIGGDFVP 242
A+++KE+C I+ +P + EGP + +EG+G FVP
Sbjct: 182 VGTGGTLMGVAKRLKEECKNVIVAGAEPAECPVAAYWFKTGKEGPWGRHEIEGVGDGFVP 241
Query: 243 DVLD--KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGK 300
D++ K ++D +A M+R+I + E L G SSGA ++SAI+ + G GK
Sbjct: 242 DIVKRYKHLLDDFVTSTSEEAIMMARKIARLEALPVGISSGANVVSAIKLGRSHGLGKGK 301
Query: 301 RVVVILPDGIRNYMT 315
+VV ILPD Y +
Sbjct: 302 KVVTILPDYAARYFS 316
>UniRef50_Q0AX09 Cluster: Cysteine synthase; n=5; Clostridiales|Rep:
Cysteine synthase - Syntrophomonas wolfei subsp. wolfei
(strain Goettingen)
Length = 305
Score = 185 bits (450), Expect = 2e-45
Identities = 104/311 (33%), Positives = 170/311 (54%), Gaps = 8/311 (2%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
++ NN+LE IG+TP+++LNR+ G + E++ K E NPGGSIKDR M+ +A+ G
Sbjct: 2 KVVNNVLELIGETPVIKLNRM-LGAG-QAEVYVKLEGFNPGGSIKDRPGLYMIEKAEARG 59
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
+ K + +E TSGNTGIG+A+A ++ G+ IV P+ SDE+ + GA+++ TPA
Sbjct: 60 LLKKDSIILEATSGNTGIGLAMAASIKGYPILIVMPENMSDERKKILRAYGAQLLLTPAE 119
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIXXX 189
E + A+ D Q++N N +H TA+EIL + +D+
Sbjct: 120 ---EGMPGAVGRARELATSDSRYFLVQQFENQDNAESHEITTAQEILRQMEHKLDIFICG 176
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
+ +K PK IV V+P S + A ++ ++GIG F+P VL+ +
Sbjct: 177 VGSGGTLSGTGKALKSSLPKIKIVAVEPAKSAVLSGNTAGVHKIQGIGAGFIPPVLNIEM 236
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDG 309
+D++ +D DA R++ KKE LL G SSGAA+ +A+ + ++ ++++ I PDG
Sbjct: 237 VDQIIPVSDEDAIETCRQMAKKEALLLGISSGAAVFAALNLVRDMD--PSQKILAIAPDG 294
Query: 310 IRNYMTKFVCD 320
YM+ + D
Sbjct: 295 AEKYMSTELFD 305
>UniRef50_Q130S8 Cluster: Cysteine synthase; n=2;
Proteobacteria|Rep: Cysteine synthase - Rhodopseudomonas
palustris (strain BisB5)
Length = 340
Score = 184 bits (449), Expect = 3e-45
Identities = 110/320 (34%), Positives = 162/320 (50%), Gaps = 13/320 (4%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
+G TPLV + ++ G+ +FAK EF+NPGGSIKDR+ ++ A++ G + G +
Sbjct: 9 VGATPLVEITKLDIPDGIR--VFAKLEFLNPGGSIKDRMVKYILDHAERVGALQPGATIV 66
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHF 139
E TSGNTG +A+ A G+ + PDK S EK + + +GA+ + P +S EH+
Sbjct: 67 ENTSGNTGAAIAMFAAERGYRAILTMPDKVSQEKQNVLRAMGAQTIVCPTAVRPDSPEHY 126
Query: 140 LSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIXXXXXXXXXXXX 198
+ A+R E P + +QY N +N H+ T EI AL +
Sbjct: 127 VETARRLHREIPGSFMLNQYDNPLNAEAHFHTTGPEIWEALGGRITAFVSSGSTGGTISG 186
Query: 199 XAQKVKEKCPKCIIVTVDPQGSL---IFGEGPAD-----LYFVEGIGGDFVPDVLDKSVI 250
++ K P +V +DP GS+ F EG D Y VEG+G D + +D SV+
Sbjct: 187 IGGYLRSKNPDIHVVLLDPVGSIYHKYFHEGVVDPREIAAYHVEGVGEDHLAKCMDFSVL 246
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
V + ND +A M E+ +KEGLLCGGSSGA + I AK L A +V +LPD
Sbjct: 247 TNVIRFNDRNAIQMCHELARKEGLLCGGSSGANIWGCIEVAKALKPPA--VIVTVLPDSG 304
Query: 311 RNYMTKFVCDQWMEAHLFKE 330
Y++K W+ F +
Sbjct: 305 AKYVSKIYNADWLAEQRFAD 324
>UniRef50_Q0SJ57 Cluster: Cysteine synthase; n=2; Bacteria|Rep:
Cysteine synthase - Rhodococcus sp. (strain RHA1)
Length = 470
Score = 182 bits (442), Expect = 2e-44
Identities = 109/322 (33%), Positives = 164/322 (50%), Gaps = 15/322 (4%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
+Y++I + IG+TPLVRLNR+ + ++AK EF+NPGGS+KDR + M+ A++SG
Sbjct: 16 VYDSITDAIGNTPLVRLNRVTGS--ISATVYAKLEFLNPGGSVKDRAALAMIHAAEESGE 73
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
G +E TSGNTG+G+ L A G+ +V PDK S EK++ + GA+V TP
Sbjct: 74 LLPGGTVVEGTSGNTGVGLTLVAAARGYRSVVVVPDKTSVEKIALLRAHGAQVHVTPGGR 133
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD--VDMIXXX 189
P E +VA R E P QY N NP H T EI +
Sbjct: 134 PSHHPEFVRNVATRLAAEIPGGWLAGQYDNPANPDAHRTTTGPEIWRQTRGRVTHFVAGV 193
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIG--------GDFV 241
K I+ DP+ S ++G G +++E +G D
Sbjct: 194 GTGGTITGTGEFLTKISGGAVKIIGADPETS-VYGGGDGRAWYIESVGHFLHPQTEHDEW 252
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
PD V+D++E+ D +A + + ++EGLL GGS+G A+ +A+R A+ L G
Sbjct: 253 PDSYHPDVVDRLERIPDIEALTVLHRLAREEGLLVGGSAGTAVAAALRVARTL--GPDDV 310
Query: 302 VVVILPDGIRNYMTKFVCDQWM 323
VVVI+PD R Y++K+ ++W+
Sbjct: 311 VVVIVPDSGRAYLSKYFDNEWL 332
>UniRef50_UPI0001597832 Cluster: YtkP; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YtkP - Bacillus
amyloliquefaciens FZB42
Length = 310
Score = 181 bits (440), Expect = 4e-44
Identities = 100/288 (34%), Positives = 154/288 (53%), Gaps = 9/288 (3%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
+I N+ E IG TP+V+LNR+ ++ +++ K E NP GS+KDR +Y M++EA+ SG
Sbjct: 2 KIVNSTAELIGGTPIVKLNRLQPEHA--AQVYLKLESFNPSGSVKDRAAYNMIIEAENSG 59
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
K G+ IEPTSGNTGIG+A+ A G+ +V PD + E+++ + GAEVV TP
Sbjct: 60 HLKPGSVIIEPTSGNTGIGLAMNAAARGYKAILVMPDTMTKERINLLKAYGAEVVLTPGA 119
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVD----MI 186
S + AK + P + Q+ N NP H + TA EI V ++
Sbjct: 120 ERMPGS---IKKAKELAEQIPGSFIPMQFDNGANPDAHRKTTAIEIYQAVQQLNRPLGAF 176
Query: 187 XXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLD 246
+ +KE P I+ +P GS + G + + G F+P +L+
Sbjct: 177 VATAGTGGTITGTGETLKELFPDMIVHVAEPAGSPVLSGGKPGAHKLVGTSPGFIPGILN 236
Query: 247 KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKL 294
+ V D++ K +D DA+ +R + ++EG+L G SSGAA +AI AK+L
Sbjct: 237 QDVYDEIMKISDEDAYTTTRRLAREEGILVGPSSGAACFAAIETAKRL 284
>UniRef50_Q3A4C8 Cluster: Cysteine synthase; n=2;
Deltaproteobacteria|Rep: Cysteine synthase - Pelobacter
carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 298
Score = 177 bits (431), Expect = 5e-43
Identities = 111/308 (36%), Positives = 168/308 (54%), Gaps = 19/308 (6%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
+ +++ E IG+ P ++L++I +FAK EF+NPGGSIKDR++ ++ A+K G
Sbjct: 2 LVSSVTELIGNVPTIQLSKISTG-----NVFAKAEFLNPGGSIKDRVARNIIDSAKKEGK 56
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
SG IE TSGNTGI +A A CG V P+ S+E+M I G E + TPA
Sbjct: 57 LTSGMTIIEATSGNTGISLAWVGAQCGHHVVCVMPENVSEERMKIIRAFGGETISTPAD- 115
Query: 132 PWESSEHFLSVAKRRL-LEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIXXX 189
E+ L AK + LE +Q+ N NP THY+ T +I L ++D+
Sbjct: 116 --ENLIGCLKKAKEIMQLEPGKYFFVNQFSNPHNPETHYKQTGAQIWDDLKGEIDIFVAG 173
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGS-LIFGEGPADLYFVEGIGGDFVPDVLDKS 248
A+ +KEK P I+ V+P+ S + G+ P L+ ++GIG F+P+VLD
Sbjct: 174 VGSGGTLQGVAKFLKEKNPAIKIIAVEPKNSATLLGKEPG-LHQIQGIGDGFIPEVLDLD 232
Query: 249 VIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGK-RVVVILP 307
++D V +D +A + +R++ ++EGLL G SSGA + +A L F G+ RVV +LP
Sbjct: 233 LVDSVFTVSDEEAIDTTRKLSRQEGLLVGTSSGANVFAA------LQFDNGRNRVVTVLP 286
Query: 308 DGIRNYMT 315
D Y +
Sbjct: 287 DRAERYFS 294
>UniRef50_O15570 Cluster: Cysteine synthase; n=8; Entamoeba|Rep:
Cysteine synthase - Entamoeba histolytica
Length = 337
Score = 177 bits (431), Expect = 5e-43
Identities = 104/316 (32%), Positives = 166/316 (52%), Gaps = 9/316 (2%)
Query: 4 SRSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLE--CEMFAKCEFVNPGGSIKDRISYT 61
S S R RIY+NILETIG TPLV L+ + + ++ + K E+ NP S+KDR+ +
Sbjct: 5 SISSPRKRIYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFN 64
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
+V +A K G K G IE TSGNTGI + A AV G+ I P S E+ + G
Sbjct: 65 IVYQAIKDGRLKPGMEIIESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFG 124
Query: 122 AEVVQTPAMAPWESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALV 180
AE++ T + + + + E+P +Q+ N N H+ YTA EI
Sbjct: 125 AELILTEGKKGMPGA---IEEVNKMIKENPGKYFVANQFGNPDNTAAHH-YTANEIWEDT 180
Query: 181 P-DVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGD 239
+VD++ A+K+KEK I+ V+P+ S + + ++GIG
Sbjct: 181 DGEVDIVVSAVGTSGTVIGVAEKLKEKKKGIKIIAVEPEESAVLEGKAKGPHGIQGIGAG 240
Query: 240 FVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAG 299
F+PD+ K +D++ DA+ M+R ++K +G++CG SSGAA+++ ++ A+K G
Sbjct: 241 FIPDIYKKEFVDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPE-NEG 299
Query: 300 KRVVVILPDGIRNYMT 315
K +V+I+P Y++
Sbjct: 300 KTIVIIVPSCGERYLS 315
>UniRef50_A0K1R0 Cluster: Cysteine synthase; n=3;
Micrococcineae|Rep: Cysteine synthase - Arthrobacter sp.
(strain FB24)
Length = 344
Score = 175 bits (427), Expect = 1e-42
Identities = 109/314 (34%), Positives = 163/314 (51%), Gaps = 11/314 (3%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSG 75
+L +G+TPLV L+ + K GL ++ K E NPGGSIKDR + +M+ A++SG + G
Sbjct: 22 VLAQVGNTPLVPLDVLGK--GLGSTVYVKLESDNPGGSIKDRTALSMIRAAERSGELRPG 79
Query: 76 TRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWES 135
+E TSGNTGIG+AL A+ G +VT D S EK++ + GA VV T AP ES
Sbjct: 80 ATIVESTSGNTGIGLALIGALTGHPVVVVTGDTISSEKLAALHRYGARVVVTDWTAPSES 139
Query: 136 SEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXX 194
E+ +VA R E+P A Q+ N NP HYE TA EI V
Sbjct: 140 PENARAVAARITAENPGAWRPQQFDNPANPLAHYEGTAPEIWQQTSGRVTHFVAGIGTGG 199
Query: 195 XXXXXAQKVKEKCPKCI-IVTVDPQGSLIFGEGPADLYFVEGIGGDFV----PDVLDKSV 249
+ +KEK + ++ DP GS+ G P ++ V+G+G + P + D+ +
Sbjct: 200 TISGNGRYLKEKTGGHVEVIAADPVGSVYSGGHPGEI-LVDGVGNSWPEAEWPKIFDRGI 258
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDG 309
+D+ + + + + ++ +EGL G SSG A+ +A+R A+ G VV I PD
Sbjct: 259 VDRFLRIPNNEVYTTEHRLLNEEGLSLGPSSGLAVAAALRVARAA--PRGSVVVAIAPDA 316
Query: 310 IRNYMTKFVCDQWM 323
NY++K W+
Sbjct: 317 GSNYLSKAFNPVWL 330
>UniRef50_Q74FS1 Cluster: Cysteine synthase A; n=25; Bacteria|Rep:
Cysteine synthase A - Geobacter sulfurreducens
Length = 307
Score = 175 bits (426), Expect = 2e-42
Identities = 102/309 (33%), Positives = 159/309 (51%), Gaps = 10/309 (3%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
+ ++E IG+TPL+RL ++ + +F K EF NPGGSIKDRI M+ A++ G K
Sbjct: 7 DKVIEQIGNTPLLRLAKLERKGS--AAVFGKAEFFNPGGSIKDRICLAMIEAAERDGTLK 64
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPW 133
G +EPTSGNTGIG+++ AV G+ + PD + E+ ++ GAE++ TP
Sbjct: 65 PGATVVEPTSGNTGIGLSMICAVKGYKLILTMPDTMTVERRRLLAAYGAELILTPGAQGM 124
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALV--PDVDMIXXXXX 191
+ + L P + Q+KN NP H T EI+ + +D
Sbjct: 125 RGA----VMKAEELAAQPGHVMMHQFKNPANPDIHRRTTGPEIVETLSGTTIDAFVAGVG 180
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVID 251
+ ++ +V V+P S + G + ++GIG FVPDVL+ V D
Sbjct: 181 TGGTITGVGEVLRTHNSSVRVVAVEPADSPVLSGGQPGPHKIQGIGAGFVPDVLNTKVYD 240
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
++ ++ DA+ R++ ++EG+L G SSGA + +A++ A KL G GK VV IL D
Sbjct: 241 EIITVSNDDAYATVRDLAREEGILVGISSGANVFAALQVAAKL--GPGKNVVTILCDTGE 298
Query: 312 NYMTKFVCD 320
Y++ V D
Sbjct: 299 RYLSTGVFD 307
>UniRef50_O32978 Cluster: Cysteine synthase A (EC 2.5.1.47)
(O-acetylserine sulfhydrylase A) (O- acetylserine
(Thiol)-lyase A); n=8; cellular organisms|Rep: Cysteine
synthase A (EC 2.5.1.47) (O-acetylserine sulfhydrylase
A) (O- acetylserine (Thiol)-lyase A) - Mycobacterium
leprae
Length = 310
Score = 175 bits (426), Expect = 2e-42
Identities = 99/305 (32%), Positives = 161/305 (52%), Gaps = 7/305 (2%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I ++ + +G+TPLVRL R+ + G ++ AK E NP S+KDRI M+ A+++G+
Sbjct: 3 IAEDVTQLVGNTPLVRLRRVTE--GALADVVAKLESFNPANSVKDRIGVAMIDTAEEAGL 60
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K T +EPTSGNTGI +A+ A G+ C + P+ S E+ + GAE++ TP
Sbjct: 61 IKPDTVILEPTSGNTGIALAMVCAARGYHCVLTMPETMSIERRMLLRAYGAELILTPGA- 119
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXX 190
+ ++ A+ D Q++N NP H TAEE+ VD+
Sbjct: 120 --DGMSGAIAKAEELAKSDKRYFIPQQFENPANPAIHAATTAEEVWRDTDGKVDIFVSGI 177
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVI 250
A+ +KE+ P V V+P S + G + ++GIG FVP VL ++
Sbjct: 178 GTGGTITGVARIIKERRPATQFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPSVLVLDLV 237
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
D++ + +A +++R + K+EGLL G S+GAA+ +A+ A++ GK +VV+LPD
Sbjct: 238 DEIVTVGNEEALDLARRLAKEEGLLVGISAGAAVCAALHVARRPE-NTGKLIVVVLPDFG 296
Query: 311 RNYMT 315
Y++
Sbjct: 297 ERYLS 301
>UniRef50_Q98DX5 Cluster: Cysteine synthase; n=42; Bacteria|Rep:
Cysteine synthase - Rhizobium loti (Mesorhizobium loti)
Length = 479
Score = 174 bits (424), Expect = 3e-42
Identities = 108/318 (33%), Positives = 164/318 (51%), Gaps = 12/318 (3%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
Y ++L+ IG TP+V L + D G +C +F K E NPGGSIKDRI+ +M+ A++ G
Sbjct: 25 YKSVLDLIGQTPVVELTKF--DTG-KCRLFIKLESQNPGGSIKDRIALSMIAAAEREGKL 81
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
K G +E T+GNTG+G+A G+ +V PDK S EK+ + LGAEV T +
Sbjct: 82 KRGGTIVEATAGNTGLGLAQVGIPKGYRIVLVVPDKMSREKIQHLRALGAEVRMTRSDVG 141
Query: 133 WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA-LVPDVDMIXXXXX 191
E++ +A++ E P A +Q+ N NP H T EI + L +VD +
Sbjct: 142 KGHPEYYQDMAEKIAAEVPGAFYANQFANPANPLAHETTTGPEIFSQLDGNVDAVVVGVG 201
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSLI-----FGE-GPADLYFVEGIGGDFVPDVL 245
+ + PK +V DP GS++ G+ A + VEGIG DFVP
Sbjct: 202 SGGTLTGLGRYFSKVSPKTEMVLADPVGSVLAPLIKTGKMEEAGSWTVEGIGEDFVPPNA 261
Query: 246 DKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVI 305
D S++ K +D + R+++ +EG+L G SSG + +A+R ++ KRVV
Sbjct: 262 DLSLVKKAYSISDKQSMLAVRDLLSREGILAGSSSGTLLSAALRYCREQT--TPKRVVTF 319
Query: 306 LPDGIRNYMTKFVCDQWM 323
+ D Y++K D W+
Sbjct: 320 VCDSGNKYLSKVFDDFWL 337
>UniRef50_Q6ANV5 Cluster: Cysteine synthase; n=2; Bacteria|Rep:
Cysteine synthase - Desulfotalea psychrophila
Length = 306
Score = 174 bits (424), Expect = 3e-42
Identities = 105/300 (35%), Positives = 159/300 (53%), Gaps = 9/300 (3%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR 77
++IG+TPL++L R+ +D + K E NP GS+K R++ +M+ + G GT
Sbjct: 7 QSIGNTPLLKLGRLDRDCA--ATILVKQESRNPAGSVKCRVAVSMIETGLREGKISKGTT 64
Query: 78 FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE 137
+EPTSGNTGIG+A A G + P+ S E+ ++ LGAE+V TPA E
Sbjct: 65 IVEPTSGNTGIGLAFVCAAKGLRLILTMPESMSIERRKLLAHLGAEIVLTPAA---EGMT 121
Query: 138 HFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXX 196
++ A+ L + DQ+ N NP H + T +EIL VD+
Sbjct: 122 GAITKAEELLTGLADGFMPDQFNNPANPEIHRQTTGKEILRDTDGRVDIFVAGVGTGGTL 181
Query: 197 XXXAQKVKEKCPKCIIVTVDPQGS-LIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEK 255
+K K P+ ++ V+P S +I GE P + ++GIG F+P LD S+ID+ K
Sbjct: 182 TGVGSVLKAKNPRVQVIAVEPATSAVISGEAPGP-HGIQGIGAGFIPGNLDISLIDETIK 240
Query: 256 PNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
ND DA ++E+ +EG+LCG SSGAA +++ AK+ GK +V ILPD Y++
Sbjct: 241 VNDEDALVAAQELATQEGILCGISSGAAFWASLEVAKRPE-NIGKTIVTILPDTGERYLS 299
>UniRef50_Q0AWJ8 Cluster: O-acetylserine (Thiol)-lyase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
O-acetylserine (Thiol)-lyase - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 343
Score = 173 bits (422), Expect = 6e-42
Identities = 105/321 (32%), Positives = 170/321 (52%), Gaps = 10/321 (3%)
Query: 10 NRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
N+I++N+LE IG TP++RLN+I + GL+ ++ AK E+VNP GS+KDR+ + +V EA+K
Sbjct: 7 NKIFDNVLEVIGRTPMIRLNKIGE--GLKPDICAKLEYVNPSGSLKDRVVHKIVEEAEKR 64
Query: 70 GIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
G K G +E T+GNTGI A+ A G+ IV P S+E+ TI+ GAE+V TP
Sbjct: 65 GDLKPGMILLEGTTGNTGIAAAMVGAAKGYRVIIVMPAGMSEERKKTIAAYGAELVLTPG 124
Query: 130 MAPWESSEHFLSVAKRRLLED--PNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMI 186
E+ + +R+ ++ Q+ + N H + TA EI ++D+
Sbjct: 125 A---ETDVDLVLEEVKRIKQEYGEQIFEVGQFYREDNLLAHIDNTAPEIWEQTAGEMDVF 181
Query: 187 XXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLD 246
A+ +KEK P + +P+ S I G + ++GI +P++LD
Sbjct: 182 IMCQGTGGTVTGTAKYLKEKNPAIKVYVSEPEDSPILACGRIGQHKIQGIADGLIPEILD 241
Query: 247 KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVIL 306
ID + + +A +R++ +KEG+ CG SSG + +AI+ AKK + K +V I+
Sbjct: 242 LQYIDGIILVSSDEALETARQMARKEGVFCGSSSGINVAAAIKVAKK--YPEKKCIVTII 299
Query: 307 PDGIRNYMTKFVCDQWMEAHL 327
D Y++ +C E L
Sbjct: 300 NDNGLRYLSTELCGTMPERQL 320
>UniRef50_UPI00015BB1D1 Cluster: Pyridoxal-5'-phosphate-dependent
enzyme, beta subunit; n=1; Ignicoccus hospitalis
KIN4/I|Rep: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit - Ignicoccus hospitalis KIN4/I
Length = 313
Score = 172 bits (418), Expect = 2e-41
Identities = 108/309 (34%), Positives = 166/309 (53%), Gaps = 19/309 (6%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR 77
E +G+TP V L R+ G + K EF+NP GSIKDR + M+ EA++ G+ K G+
Sbjct: 8 EAVGNTPAVLLRRLTSGKG---NVMVKLEFMNPSGSIKDRPALYMIKEAEERGLLKPGST 64
Query: 78 FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE 137
+EP+SGNT + +A+ A G+ V P+ S++K+ + LLGA+V+ + A P E
Sbjct: 65 IVEPSSGNTALSLAMLAAAKGYKMVAVVPETTSEQKVKMMELLGAKVIFSKAGVPLGHPE 124
Query: 138 HFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL----ALVPDVDMIXXXXXXX 193
H ++AK RL E+ + DQYKN+ N R HYE T E+L L+ +D
Sbjct: 125 HHYTLAK-RLAEENGWVMLDQYKNEANVRAHYETTGPEVLKQARELMGGLDAFVAGVGTG 183
Query: 194 XXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG----EGPADLYFVEGIGGDFVPDVLD--K 247
+ +KE+ +V V P+G+ I G EG + +EG+ V +++ K
Sbjct: 184 GTVIGVGKFLKERVKGVKVVAVVPKGTKIAGFFGSEGERLSHAIEGLTAMPVSELIKKYK 243
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
VID++ + +D +A +RE+ KEGLL G S+GA +RAA +L G RV + P
Sbjct: 244 HVIDEIIEVDDEEAVKTARELASKEGLLAGLSAGA----NVRAALELE-REGLRVATVAP 298
Query: 308 DGIRNYMTK 316
DG Y+ +
Sbjct: 299 DGAIRYLER 307
>UniRef50_Q9REQ7 Cluster: Cysteine synthase; n=6;
Proteobacteria|Rep: Cysteine synthase - Zymomonas
mobilis
Length = 337
Score = 171 bits (417), Expect = 2e-41
Identities = 108/319 (33%), Positives = 159/319 (49%), Gaps = 12/319 (3%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
NIL IG+T LVRL + G C ++AKCEF NPGGSIKDR + +++ +A++ GI +
Sbjct: 14 NILSMIGNTSLVRLEGPSELTG--CNIYAKCEFTNPGGSIKDRAALSIIEDAEEQGIIEP 71
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
G +E T+GNTGIG+ L A G+ IV P+ S EK++T+ LGAE+V P + +
Sbjct: 72 GGVIVEGTTGNTGIGLTLVGAAKGYHTIIVMPETQSSEKIATLQALGAELVLVPETS-YS 130
Query: 135 SSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXXXX 193
+S H++ +++R E NAI +Q+ N N H + T++EI A +D
Sbjct: 131 NSAHYVHMSRRLAQETDNAIWANQFDNLANRMAHIKTTSQEIWAQTEGHIDGFICAAGTG 190
Query: 194 XXXXXXAQKVKEKCPKCIIVTVDPQGS------LIFGEGPADLYFVEGIGGDFVPDVLDK 247
+ E P ++ DP G+ L G + F EG G V LD
Sbjct: 191 GTFAGTGLGLIEHNPDIVVALADPYGAVYIIIILAVNCGQRGILFAEGFGQSRVTGNLDG 250
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
+ +D +D + S KK L G G+ AI+ AK+L G GK +V IL
Sbjct: 251 APVDNQFLISDQEGLRKSISCFKKRDCLLGCRRGSISAGAIKLAKEL--GPGKTIVTILA 308
Query: 308 DGIRNYMTKFVCDQWMEAH 326
D Y++ W+ AH
Sbjct: 309 DSGLRYLSTLYNRHWLIAH 327
>UniRef50_A6SDF3 Cluster: Cysteine synthase; n=1; Botryotinia
fuckeliana B05.10|Rep: Cysteine synthase - Botryotinia
fuckeliana B05.10
Length = 448
Score = 171 bits (416), Expect = 3e-41
Identities = 83/159 (52%), Positives = 108/159 (67%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR 77
E IG+TPLVRLN+IP+ G+E E++AK E N GGSIKDRI+ M+ EA+KSG K G
Sbjct: 19 ELIGNTPLVRLNKIPQSLGIEAEVYAKVELFNAGGSIKDRIALRMIEEAEKSGRIKPGDT 78
Query: 78 FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE 137
IEPTSGNTGIG+AL A+ G+ I P+K S EK++ + LGA +++TP A W++ E
Sbjct: 79 LIEPTSGNTGIGLALVGAIKGYKTIITLPEKMSPEKVAVLRALGATIIRTPTQAAWDAPE 138
Query: 138 HFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI 176
+ VA+R L E PN+ DQY N+ NP H TAEEI
Sbjct: 139 SHIGVARRLLKEIPNSHILDQYANENNPNAHEFGTAEEI 177
Score = 48.4 bits (110), Expect = 4e-04
Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 14/108 (12%)
Query: 235 GIGGDFVPDVLDKSVIDKVEKPNDYDA--FNMSREIIKKEG-----LLCGGSSGAAMISA 287
G+ + ++ + ++D+ N+ +A F + EI ++ G ++ G +G +
Sbjct: 142 GVARRLLKEIPNSHILDQYANENNPNAHEFGTAEEIWEQTGGKITAVVAGAGTGGTITGL 201
Query: 288 IRAAKKLN-------FGAGKRVVVILPDGIRNYMTKFVCDQWMEAHLF 328
+ KK N G G VVVILPD IR+Y++KF D W+ A+ F
Sbjct: 202 SKGLKKHNKDVRDLALGKGDTVVVILPDSIRSYLSKFADDDWLAANDF 249
>UniRef50_Q43725 Cluster: Cysteine synthase, mitochondrial precursor
(EC 2.5.1.47) (O- acetylserine sulfhydrylase)
(O-acetylserine (Thiol)-lyase); n=470; cellular
organisms|Rep: Cysteine synthase, mitochondrial
precursor (EC 2.5.1.47) (O- acetylserine sulfhydrylase)
(O-acetylserine (Thiol)-lyase) - Arabidopsis thaliana
(Mouse-ear cress)
Length = 430
Score = 170 bits (414), Expect = 5e-41
Identities = 105/306 (34%), Positives = 157/306 (51%), Gaps = 8/306 (2%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I +N+ + IG TP+V LN I K G + AK E + P S+KDRI Y+MV +A++ G
Sbjct: 113 IADNVSQLIGKTPMVYLNSIAK--GCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGF 170
Query: 72 AKSGTR-FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
G +EPTSGNTGIG+A A G+ + P S E+ + GAE+V T
Sbjct: 171 ISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTD-- 228
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXX 189
P + + A+ L P+A Q+ N NP+ HYE T EI VD+
Sbjct: 229 -PAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAG 287
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
+ +KEK PK ++ V+P S I G + ++GIG F+P LD+ +
Sbjct: 288 IGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKI 347
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDG 309
+D+V + +A ++++ KEGL+ G SSGAA +AI+ AK+ AGK + V+ P
Sbjct: 348 MDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPE-NAGKLIAVVFPSF 406
Query: 310 IRNYMT 315
Y++
Sbjct: 407 GERYLS 412
>UniRef50_P71128 Cluster: Cysteine synthase B (EC 2.5.1.47)
(O-acetylserine sulfhydrylase B) (O- acetylserine
(Thiol)-lyase B); n=39; cellular organisms|Rep: Cysteine
synthase B (EC 2.5.1.47) (O-acetylserine sulfhydrylase
B) (O- acetylserine (Thiol)-lyase B) - Campylobacter
jejuni
Length = 299
Score = 170 bits (413), Expect = 7e-41
Identities = 106/306 (34%), Positives = 164/306 (53%), Gaps = 14/306 (4%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
+++ + E IG+TP++ L K +G+ +FAKCEF+NP SIKDR ++ M+ +A S
Sbjct: 2 KVHEKVSELIGNTPIIHL----KKFGIN--VFAKCEFLNPSHSIKDRAAFEMIKDALDSK 55
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
T +E TSGNTGI +A+ A G V P+ S E+ I+L GA + TPA
Sbjct: 56 KINQDTTIVEATSGNTGISLAMICADLGLKFIAVMPESMSLERRKMITLFGARLELTPAN 115
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA-LVPDVDMIXXX 189
+ + + A LL PN+ Q++N N H + TA EIL L ++D+
Sbjct: 116 LGMKGA---VDKANEILLNTPNSFMVSQFENISNKNAHRKNTALEILRDLDNELDIFVAG 172
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
+ +KEK K IV V+P S + +G A + ++GIG +F+P +L+K V
Sbjct: 173 FGTGGTISGVGEILKEKLEKVHIVGVEPLNSPLLSKGEAGSHKIQGIGANFIPAILNKEV 232
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDG 309
ID+V ++ DA N ++E + K GL+ G SSGA + +A AKK KR++ +L D
Sbjct: 233 IDEVITVSNEDAINTAKE-LAKSGLMVGISSGANVFAASMLAKKF---PDKRILTMLNDT 288
Query: 310 IRNYMT 315
Y++
Sbjct: 289 AERYLS 294
>UniRef50_A6GJR2 Cluster: Cysteine synthase; n=1; Plesiocystis
pacifica SIR-1|Rep: Cysteine synthase - Plesiocystis
pacifica SIR-1
Length = 315
Score = 168 bits (408), Expect = 3e-40
Identities = 108/312 (34%), Positives = 163/312 (52%), Gaps = 15/312 (4%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
+ IL+ IGDTPL+ L R+ + GL ++ KCE +NPGGS+KDR++ +V +A+ G+ +
Sbjct: 2 SGILDAIGDTPLLPLERLAR--GLPNPVYVKCEHLNPGGSVKDRLARAIVDDAEARGVLR 59
Query: 74 --SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
+G IE T+GNTG+G+AL A G+ V P+K S +K ++ +GA VV T A
Sbjct: 60 PHAGMTLIEATAGNTGMGLALVAAARGYALVCVMPEKMSVDKRRALAAMGARVVVTKN-A 118
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXX 191
P S ++F +VA RR+ ED +Q+ N VN H T EIL +
Sbjct: 119 PPSSPDNFQNVA-RRMAEDEGWFLTEQFDNPVNVEVHAATTGPEILRQLGRAPAAFVSGA 177
Query: 192 XXXXXXXXAQK-VKEKCPKCIIVTVDPQGSLIFG------EGPADLYFVEGIGGDFVPDV 244
+ +K P +V DP GS + G GP Y VEGIG P
Sbjct: 178 GTGGTISGVGRCLKRADPSTRVVLADPVGSGLAGWVATGEMGPDGAYAVEGIGSSKAPAN 237
Query: 245 LDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVV 304
L ++VID+ +D +F +R +I++EG+L GGS+G + +A+ A + G VV
Sbjct: 238 LHRAVIDEAVSISDERSFATARALIREEGMLVGGSAGTNVAAALELAARPELGG--PVVT 295
Query: 305 ILPDGIRNYMTK 316
+L D Y ++
Sbjct: 296 VLCDSWDRYFSQ 307
>UniRef50_Q9XEA7 Cluster: Cysteine synthase; n=10; Oryza sativa|Rep:
Cysteine synthase - Oryza sativa (Rice)
Length = 357
Score = 167 bits (407), Expect = 4e-40
Identities = 103/311 (33%), Positives = 153/311 (49%), Gaps = 6/311 (1%)
Query: 6 SFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLE 65
S I +NI + IG TPLV + I K+ G++ + K E P S+KDR + M+ +
Sbjct: 34 SSREENIASNITQLIGWTPLVEMKNIAKNEGVQARLVGKMEAYQPLCSVKDRSALRMIED 93
Query: 66 AQKSGIAKSG-TRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
A++ G+ G T IEPTSGN GIG+ L G+ V P K S +K + LGAE+
Sbjct: 94 AEEKGLITPGVTTLIEPTSGNLGIGLVLVAVQKGYRFIAVMPAKYSLDKQMLLRFLGAEL 153
Query: 125 VQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA-LVPDV 183
+ T P + + + PN+ +Q N NP H+ +T EI V
Sbjct: 154 ILTD---PAIGFNGMMDKVEELMKSIPNSHCLNQVTNPANPEAHFMWTGPEIWKDTAGKV 210
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPD 243
D+ + +K K P IV V+P S + G + ++G G F+P+
Sbjct: 211 DVFVASVGSGGTLTGVGRYLKMKNPSINIVCVEPSESPVISGGSPGPHKIQGTGAGFIPE 270
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVV 303
+LDKSVID+V N ++ M+R + K+EGLL G SSGA + + I+ A + GK +V
Sbjct: 271 ILDKSVIDEVVTVNTEESMAMARRLAKEEGLLVGISSGANVAACIKIADR-EENKGKMIV 329
Query: 304 VILPDGIRNYM 314
+ P G YM
Sbjct: 330 TMFPSGGERYM 340
>UniRef50_Q54CN7 Cluster: Cysteine synthase; n=1; Dictyostelium
discoideum AX4|Rep: Cysteine synthase - Dictyostelium
discoideum AX4
Length = 378
Score = 167 bits (407), Expect = 4e-40
Identities = 102/335 (30%), Positives = 168/335 (50%), Gaps = 22/335 (6%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I N I+ET+G+TPL+R+ + + G CE++ K EF+NPGGS KDR++ ++L+ +K G+
Sbjct: 38 ISNGIIETVGNTPLIRIKSLSEATG--CEIYGKAEFMNPGGSPKDRVAREIILDGEKKGL 95
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K G+ +E T+G+TGI + + G+ + PD S EK+ + +LGAE P +
Sbjct: 96 LKKGSTIVEATAGSTGISLTMLGKSRGYNVQLFIPDNVSKEKVDLLEMLGAETKIVPIVG 155
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXX 190
++ HF+ A +R L D A +Q+ N N HY TA+EI DVD
Sbjct: 156 -MNNANHFMHCAYQRCLGDDMAFYANQFDNLSNFNAHYNGTAKEIWEQTKGDVDGFVAAA 214
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF---GEG----PADLY---------FVE 234
+ +KE P +DP GS ++ G P D F E
Sbjct: 215 GTGGTVAGISSYLKEVNPNIQNWLIDPPGSGLYSLVNTGVIFHPKDRLVVEKLGPRSFYE 274
Query: 235 GIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKL 294
G+G + + +K+ ++ + + + +M+ ++K +GL GGSS + A++ A+KL
Sbjct: 275 GVGVNKKTENFNKASLNGAFRGTEEEGVDMAHYLLKHDGLFLGGSSALNCVGAVKLARKL 334
Query: 295 NFGAGKRVVVILPDGIRNYMTKFVCDQWMEAHLFK 329
G GK +V +L D Y ++ W+ H F+
Sbjct: 335 --GPGKTIVTVLCDSGHRYTSRLYSKSWLNDHNFQ 367
>UniRef50_O59701 Cluster: Cysteine synthase 1 (EC 2.5.1.47)
(O-acetylserine sulfhydrylase 1) (O- acetylserine
(Thiol)-lyase 1); n=32; cellular organisms|Rep: Cysteine
synthase 1 (EC 2.5.1.47) (O-acetylserine sulfhydrylase
1) (O- acetylserine (Thiol)-lyase 1) -
Schizosaccharomyces pombe (Fission yeast)
Length = 351
Score = 167 bits (406), Expect = 5e-40
Identities = 118/341 (34%), Positives = 170/341 (49%), Gaps = 20/341 (5%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I + + IG TPL+RLN + + G C + AK EF NPGGS+KDR +Y +V +A+K G
Sbjct: 13 IVSGFIGAIGRTPLIRLNTLSNETG--CNILAKAEFQNPGGSVKDRAAYYVVRDAEKKGK 70
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
G +E T+GNTGIG+A G+ C I P+ S K+ T+ LGAEV P +A
Sbjct: 71 LSRGGTIVEGTAGNTGIGLAHIARARGYKCVIYMPNTQSQAKIDTLKFLGAEVHPVP-VA 129
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXX 190
P+ + ++ A+R PNA DQ+ N N +HYE T EI VD
Sbjct: 130 PFSNPLNYNHQARRHAESTPNASWTDQFDNVANLLSHYETTGPEIWDQTKGTVDGFTCST 189
Query: 191 XXXXXXXXXAQKVKEKCP-KCIIVTVDPQGSLIF------GEGPAD--LYFVEGIG-GDF 240
+ +KEK + DP GS+++ G+ P + F EGIG G
Sbjct: 190 GTGGTFAGVTKYLKEKSDGRVASFVADPPGSVLYSHIKTKGKHPDNKGSSFTEGIGQGRI 249
Query: 241 VPDVLD-KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAG 299
+V +ID K D + NM ++ +EGL GGSS +++A+ AK L G G
Sbjct: 250 TGNVQPVYDLIDDAMKIPDEKSINMFFRLLDQEGLFLGGSSCLNVVAAVEMAKIL--GPG 307
Query: 300 KRVVVILPDGIRNYMTKFVCDQWMEA-HLFK--EPPEREFL 337
K VV IL D Y T+ ++E+ LF EP ++++
Sbjct: 308 KTVVTILCDSGHKYATRLFSRSFLESKKLFDVIEPQYKKYI 348
>UniRef50_Q59447 Cluster: Cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O- acetylserine
(Thiol)-lyase); n=19; Bacteria|Rep: Cysteine synthase
(EC 2.5.1.47) (O-acetylserine sulfhydrylase) (O-
acetylserine (Thiol)-lyase) - Flavobacterium sp. (strain
K3-15 / DSM ID92-509)
Length = 307
Score = 166 bits (404), Expect = 9e-40
Identities = 94/266 (35%), Positives = 144/266 (54%), Gaps = 7/266 (2%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
+ N LETIG+TP+V++N + + + E++ K E NPGGSIKDRI+ M+ +A+ G+
Sbjct: 3 FQNALETIGNTPVVKINNL---FNSDHEIWIKLEKSNPGGSIKDRIALAMIEDAEAKGLL 59
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
+ IEPTSGNTGIG+AL AV G+ +V P+ S E+ + GAE V TP
Sbjct: 60 NKDSTIIEPTSGNTGIGLALVAAVKGYKLILVMPESMSIERRKIMEAYGAEFVLTPREKG 119
Query: 133 WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXX 191
+ + + A E PN+ Q+ N N + H E TA+EIL P+ +D +
Sbjct: 120 MKGA---IEKANELAEETPNSWIPRQFDNPANVKIHVETTAQEILQDFPEGLDYVITGVG 176
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVID 251
A+ +KEK P ++ V+P+ S + G + ++G+G FVP +LD +++D
Sbjct: 177 TGGHITGIAKALKEKYPNLKVIAVEPELSPVLSGGSPAPHPLQGLGAGFVPSILDITLLD 236
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCG 277
V +A+ + KKEGL CG
Sbjct: 237 GVITVGKDEAYEYAINAAKKEGLFCG 262
>UniRef50_A0LFH6 Cluster: Cysteine synthase; n=6; cellular
organisms|Rep: Cysteine synthase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 773
Score = 166 bits (403), Expect = 1e-39
Identities = 112/349 (32%), Positives = 182/349 (52%), Gaps = 23/349 (6%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
+++N+LE+IG+TPL+R+NR+ + + ++AK E NPGGSIKDR + M+ A++ G+
Sbjct: 4 VFSNVLESIGNTPLIRINRLNPNPAVT--LYAKLEAKNPGGSIKDRTALFMIESAERDGL 61
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
IE TSGNTGIG+A+ AV G+ + P+ S E+ + LGAE++ TP
Sbjct: 62 LTHEKIIIEATSGNTGIGLAIVAAVKGYRLMLAMPETASLERQKILKALGAEILLTPGNL 121
Query: 132 PWESS-EHFLSVAKRRLLEDPNAISC-DQYKNDVNPRTHYEYTAEEILALVP-DVDMIXX 188
+ + E S+ + E+P+ DQ+ N NP H+ T EI V+ +
Sbjct: 122 GTDGAIEKVYSLVR----ENPDRYYMPDQFNNPANPAAHHFGTGPEIFEQTEGKVNTVVV 177
Query: 189 XXXXXXXXXXXAQKVKEKCPKCIIVTVDP-QGSLIFGEGPADLYFVEGIGGDFVPDVLDK 247
Q +KE+ P +V V+P G + G ++ + +VP + D+
Sbjct: 178 TLGTTGTAMGILQAMKERDPAIRVVGVEPYPGHRVQG--------LKNMKESYVPGIFDR 229
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
+D++ D DAF M+R + ++EG+ G SSGAAM A+R A+++ G VV +LP
Sbjct: 230 HALDQIIHIKDEDAFEMARRLAREEGIFTGMSSGAAMAIAVRVAEEMREGI---VVAVLP 286
Query: 308 DGIRNYMTKFVCDQWMEAHL-FKEPPEREFLFFKGVLTKDSLRSEATNP 355
DG Y++ + +E F ER+ + FK V+ + +R T P
Sbjct: 287 DGGDRYLSTNLFTTLLEPDFHFFNFLERKKVDFKPVV-EGKVRICVTGP 334
>UniRef50_Q8L0X3 Cluster: L-cysteine desulfhydrase; n=4;
Fusobacterium nucleatum|Rep: L-cysteine desulfhydrase -
Fusobacterium nucleatum
Length = 306
Score = 165 bits (401), Expect = 2e-39
Identities = 106/305 (34%), Positives = 163/305 (53%), Gaps = 10/305 (3%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
N++++ IG+TPLV++N I +G E ++ K E NPG S KDRI+ M+ EA+K G+
Sbjct: 4 NSVIDLIGNTPLVKINNI-NTFGNE--IYVKLEGSNPGRSTKDRIALKMIEEAEKEGLID 60
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPW 133
T IE TSGNTGIG+A+ AV + IV PD S E++ + G EV+ T
Sbjct: 61 KDTVIIEATSGNTGIGLAMICAVKNYKLKIVMPDTMSVERIQLMRAYGTEVILTDGSFGM 120
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXX 192
++ L K+ ++ +Q+ N NP+ HYE TAEEIL + + VD+
Sbjct: 121 KACLEKLEELKK---QEKKYFIPNQFTNVNNPKAHYETTAEEILRDMDNKVDVYICGTGT 177
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDF--VPDVLDKSVI 250
A+K+KEK P V+P S + +G + ++G+G +P V D S+
Sbjct: 178 GGSFSGTAKKLKEKLPNIKTYPVEPASSPLLSKGYIGPHKIQGMGMSIGGIPVVYDGSLA 237
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
D + D +AF M RE+ KEG+L G S+GA + +A+ +K+ N R+VV+ D
Sbjct: 238 DGILVCEDDEAFKMMRELSFKEGILAGISTGATLKAALDYSKE-NANKSLRIVVLSTDSG 296
Query: 311 RNYMT 315
Y++
Sbjct: 297 EKYLS 301
>UniRef50_P56067 Cluster: Cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O- acetylserine
(Thiol)-lyase); n=41; Bacteria|Rep: Cysteine synthase
(EC 2.5.1.47) (O-acetylserine sulfhydrylase) (O-
acetylserine (Thiol)-lyase) - Helicobacter pylori
(Campylobacter pylori)
Length = 306
Score = 165 bits (401), Expect = 2e-39
Identities = 100/306 (32%), Positives = 157/306 (51%), Gaps = 7/306 (2%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I + + IG TP+ + L ++AK E +NPGGS+KDR+ ++ E K+G
Sbjct: 3 IITTMQDAIGRTPVFKFTNKDYPIPLNSAIYAKLEHLNPGGSVKDRLGQYLIGEGFKTGK 62
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
S T IEPT+GNTGI +AL V P+K S EK + LGA V+ TP
Sbjct: 63 ITSKTTIIEPTAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGALVINTPTS- 121
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIXXXX 190
E + +K P++ Q++N NP +Y A EI+ L ++
Sbjct: 122 --EGISGAIKKSKELAESIPDSYLPLQFENPDNPAAYYHTLAPEIVQELGTNLTSFVAGI 179
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVI 250
A+ +KE+ P ++ V+P+GS++ G P + +EGIG +F+P + I
Sbjct: 180 GSGGTFAGTARYLKERIPAIRLIGVEPEGSILNGGEPGP-HEIEGIGVEFIPPFFENLDI 238
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
D E +D + F+ +R++ KK GLL G SSGAA ++A++ A++L G +V+ I PD
Sbjct: 239 DGFETISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALKEAQRL--PEGSQVLTIFPDVA 296
Query: 311 RNYMTK 316
Y++K
Sbjct: 297 DRYLSK 302
>UniRef50_Q6MM94 Cluster: Cysteine synthase; n=3;
Deltaproteobacteria|Rep: Cysteine synthase -
Bdellovibrio bacteriovorus
Length = 329
Score = 165 bits (400), Expect = 3e-39
Identities = 101/325 (31%), Positives = 162/325 (49%), Gaps = 11/325 (3%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
++ + +G TPL++L + K G CE+FAK E++NPGGS+KDR + ++ A+K G+ K
Sbjct: 5 SVSDVVGHTPLIKLQSLSKITG--CEIFAKAEYLNPGGSVKDRTALGIIQSAEKQGLLKP 62
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
G +E T+GNTGIG+A A G+ C IV PD S EK + LG E+V+ A P+
Sbjct: 63 GDTIVEGTAGNTGIGLATLAAQRGYHCVIVMPDNQSKEKYHALEALGVELVKV-APCPFA 121
Query: 135 SSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXX 193
+ HF A+ PN+ +Q++N N HY+ T EI + VD
Sbjct: 122 NPNHFYHTARALAESRPNSFWANQFENTANFEIHYKTTGPEIWEQMGQRVDAFVSSVGTG 181
Query: 194 XXXXXXAQKVKEKCPKCIIVTVDPQGSLIF-----GEGPAD-LYFVEGIGGDFVPDVLDK 247
+ +KE+ PK + DP GS ++ G+ A EGIG + + K
Sbjct: 182 GTLAGVSAYLKEQDPKVFTLLADPMGSGLYSFVKSGKFEAQGSSITEGIGIMRLTENFKK 241
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
+ +D+ + +D +M + + EGLL G S+ + ++ + A + N G G R+ ++
Sbjct: 242 ARVDEAVQIHDEQMLSMLYYLAQHEGLLVGTSAALNIFASYQYALQ-NQGKGLRIATVMG 300
Query: 308 DGIRNYMTKFVCDQWMEAHLFKEPP 332
D Y +K Q++ K P
Sbjct: 301 DSALRYQSKVFNPQFLNEKNLKIMP 325
>UniRef50_Q4PAS1 Cluster: Cysteine synthase; n=1; Ustilago
maydis|Rep: Cysteine synthase - Ustilago maydis (Smut
fungus)
Length = 404
Score = 165 bits (400), Expect = 3e-39
Identities = 81/170 (47%), Positives = 112/170 (65%), Gaps = 2/170 (1%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I + L +G+TPL++LNRIP+ G++C + KCEF N GGS+KDRI+ M+L+A++ G
Sbjct: 6 ILPDALSAVGETPLIQLNRIPQSEGIKCNVMVKCEFFNAGGSVKDRIARRMLLQAEQDGT 65
Query: 72 AKSGTRF-IEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
G IEPTSGNTGIG+ALA A+ G+ C IV P+K S EK++T+ LGAEV++TP
Sbjct: 66 LIPGKSVVIEPTSGNTGIGLALACAIRGYRCIIVLPEKMSAEKVNTLRALGAEVIRTPTE 125
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALV 180
A + + VA+R PNA+ DQY N NP H+ TAEEI+ +
Sbjct: 126 AAHDDPRSNIMVARRLAKSMPNAVILDQYNNPNNPTAHWA-TAEEIIQAI 174
Score = 89.8 bits (213), Expect = 1e-16
Identities = 56/124 (45%), Positives = 70/124 (56%), Gaps = 15/124 (12%)
Query: 208 PKCIIVTVDPQGSLI--------FGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDY 259
P C ++ VDP GS + EG Y VEGIG DF P+ L+K VID+ K D
Sbjct: 259 PDCFVLGVDPIGSDLALPVSLNALPEGSDGSYKVEGIGYDFDPNTLNKKVIDEWYKTEDE 318
Query: 260 DAFNMSREIIKKEGLLCGGSSGAAMISAIRAAK-------KLNFGAGKRVVVILPDGIRN 312
+F +R +IK EG+L GGSSGAA+ +AI K K AG VV+LPD IRN
Sbjct: 319 QSFVYARRLIKDEGILAGGSSGAAVNAAINWLKPGGAGWDKFGSKAGLNAVVVLPDSIRN 378
Query: 313 YMTK 316
Y+TK
Sbjct: 379 YITK 382
>UniRef50_P38076 Cluster: Cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O- acetylserine
(Thiol)-lyase); n=21; Magnoliophyta|Rep: Cysteine
synthase (EC 2.5.1.47) (O-acetylserine sulfhydrylase)
(O- acetylserine (Thiol)-lyase) - Triticum aestivum
(Wheat)
Length = 325
Score = 163 bits (397), Expect = 6e-39
Identities = 99/306 (32%), Positives = 157/306 (51%), Gaps = 8/306 (2%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I ++ E IG+TPLV LN++ G + AK E + P S+KDRI Y+M+ +A++ G
Sbjct: 9 IAKDVTELIGNTPLVYLNKVTD--GCVGRVAAKLESMEPCSSVKDRIGYSMITDAEEKGF 66
Query: 72 AKSGTR-FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
G IEPTSGNTGIG+A A G+ + P S E+ + GAE++ T +
Sbjct: 67 IVPGKSVLIEPTSGNTGIGLAFMAAAKGYRLVLTMPASMSMERRIILKAFGAELILTDPL 126
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIXXX 189
+ + + A+ + PN+ Q++N NP+ HYE T EI +D +
Sbjct: 127 LGMKGA---VQKAEELAAKTPNSYILQQFENAANPKIHYETTGPEIWKGTGGKIDGLVSG 183
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
+ ++E+ P + V+P S I G + ++GIG F+P VLD +
Sbjct: 184 IGTGGTITGTGKYLQEQNPNIKLYGVEPTESAILNGGKPGPHKIQGIGAGFIPGVLDVDI 243
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDG 309
ID+ + + ++ M++ + KEGLL G SSGAA +AI+ A++ AGK VV+ P
Sbjct: 244 IDETIQVSSDESIEMAKSLALKEGLLVGISSGAAAAAAIKVAQRPE-NAGKLFVVVFPSF 302
Query: 310 IRNYMT 315
Y++
Sbjct: 303 GERYLS 308
>UniRef50_Q9RW80 Cluster: Cysteine synthase; n=13; Bacteria|Rep:
Cysteine synthase - Deinococcus radiodurans
Length = 317
Score = 161 bits (390), Expect = 4e-38
Identities = 97/297 (32%), Positives = 156/297 (52%), Gaps = 9/297 (3%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
IG TPLV+L R+ ++F K E NPGGSIKDR + +V +A++ G+ K G +
Sbjct: 6 IGHTPLVQLRRVVTPD--MADVFIKLEGQNPGGSIKDRTALGLVQDAERRGVLKPGGTIV 63
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHF 139
EPTSGNTGIG+A A G+ + P + S+E+ T+ GAE++ T P
Sbjct: 64 EPTSGNTGIGLAQVAAAKGYKLILCMPAQMSEERKRTLRAYGAELILTD---PERRMLAA 120
Query: 140 LSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXXXX 198
+ A+ ++ + A+ +Q+ N NP TH T E+ + VD
Sbjct: 121 IEEAE-KIAAETGAVMMNQFANPANPATHEASTGPELWEQMEGRVDAFVYGTGTGGTITG 179
Query: 199 XAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPND 258
+ +K + P ++ +P S + G + +G+G F+PD LD+S++D V + +
Sbjct: 180 TGRYLKRQDPNIQVIACEPARSNVLSGGERGNHGFQGMGPGFIPDNLDRSLLDDVIQVWE 239
Query: 259 YDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
DA+ ++R + ++EG+ G SSGA + +A+ A++L G GKRVV I D Y+T
Sbjct: 240 EDAYPLARRLAQEEGIFIGMSSGAMVWTALEVARRL--GPGKRVVTIACDTGARYLT 294
>UniRef50_A5IQ12 Cluster: Cysteine synthase; n=16;
Staphylococcus|Rep: Cysteine synthase - Staphylococcus
aureus subsp. aureus JH9
Length = 318
Score = 160 bits (389), Expect = 6e-38
Identities = 98/299 (32%), Positives = 158/299 (52%), Gaps = 13/299 (4%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR 77
+ IG+TPLV L D + +++AK E NPGGS+KDR+ +V +A + G ++G
Sbjct: 22 DLIGNTPLVLLEHYSDD---KVKIYAKLEQWNPGGSVKDRLGKYLVEKAIQEGRVRAGQT 78
Query: 78 FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE 137
+E T+GNTGIG+A+A C I P S+EK++ + LGA+V +T
Sbjct: 79 IVEATAGNTGIGLAIAANRHHLKCKIFAPYGFSEEKINIMIALGADVSRTSQ----SEGM 134
Query: 138 HFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXX 197
H +A R E A+ +Q++++ NP T++ E+ + + +D
Sbjct: 135 HGAQLAARSYAEKYGAVYMNQFESEHNPDTYFHTLGPELTSALQQIDYFVAGIGSGGTFT 194
Query: 198 XXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPN 257
A+ +K+ +C V+P+GS++ G GPA + EGIG + P L++ ++D +
Sbjct: 195 GTARYLKQHHVQC--YAVEPEGSVLNG-GPAHAHDTEGIGSEKWPIFLERRLVDGIFTIK 251
Query: 258 DYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTK 316
D DAF + + EGLL G SSGAA+ A+ +L+ G +VV+ PDG YM+K
Sbjct: 252 DQDAFRNVKSLAINEGLLVGSSSGAALQGALNLKAQLSEGT---IVVVFPDGSDRYMSK 307
>UniRef50_Q7VHW4 Cluster: Cysteine synthase; n=2;
Campylobacterales|Rep: Cysteine synthase - Helicobacter
hepaticus
Length = 300
Score = 159 bits (386), Expect = 1e-37
Identities = 100/305 (32%), Positives = 156/305 (51%), Gaps = 14/305 (4%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I NI E IG+TP+++L + + ++ KCEF+NP S+KDR +Y M+ EA K+G
Sbjct: 2 IAQNITELIGNTPILQLQQFAPN------LYGKCEFLNPSHSVKDRPAYAMIDEALKTGK 55
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
T +E TSGN GI +A+ A G I P+ S E+ I+L GA +V TPA
Sbjct: 56 ITKDTTIVECTSGNMGISLAMICASLGLKIIITMPESMSIERRKMIALFGANLVLTPAS- 114
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIXXXX 190
E + L+ A+ L PN+ Q+ N N H TA EI + +D
Sbjct: 115 --EGMQGALNKAQEILDSTPNSFMPSQFDNLANKEMHKRTTALEIYKSFEGSLDYFVAGF 172
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVI 250
+ +KEK P I+ V+P S + +G A + ++GIG +F+P +L++ VI
Sbjct: 173 GTGGTISGVGEVLKEKIPSIKIIGVEPAASPLLSKGQAGPHKIQGIGANFIPKILNRDVI 232
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
D +E + A M++ + K G++ G SSGA + +A+ AK K+V+ +L D
Sbjct: 233 DSIEVVENEVAIKMAQN-LGKIGVMVGISSGANVAAALEIAKN---NPNKKVLTMLNDTA 288
Query: 311 RNYMT 315
Y++
Sbjct: 289 ERYLS 293
>UniRef50_Q4AMJ6 Cluster: Cysteine synthase K/M:Cysteine synthase A;
n=1; Chlorobium phaeobacteroides BS1|Rep: Cysteine
synthase K/M:Cysteine synthase A - Chlorobium
phaeobacteroides BS1
Length = 328
Score = 159 bits (385), Expect = 2e-37
Identities = 106/314 (33%), Positives = 152/314 (48%), Gaps = 8/314 (2%)
Query: 3 NSRSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTM 62
N + F R N+I +G TPLV L+R+ D L + AK E NP GS+KDR + M
Sbjct: 16 NGKGFGVLRYVNDITGLVGSTPLVALSRLFGDGNL---VLAKLEQFNPCGSVKDRAALAM 72
Query: 63 VLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGA 122
+ A + G + G IE TSGNTGI +A AV + +V PD S E+ +++ GA
Sbjct: 73 IQRAVEDGELRPGGTVIEATSGNTGIALAFIAAVRKYRLIVVMPDSMSIERRKLLAVFGA 132
Query: 123 EVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD 182
V TPA E + ++ A N+ Q+ N N H TA EIL
Sbjct: 133 GVELTPAHLGMEGA---ITRAGELQASLENSFLVRQFDNPSNAAVHENTTALEILQDTDG 189
Query: 183 -VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFV 241
VD+I A+KVK++ P+ IV V+P PA + ++GIG FV
Sbjct: 190 GVDVIVAGVGTGGTITGIARKVKKERPEARIVAVEPANCAALSGKPAGPHGIQGIGAGFV 249
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
P ++DK +ID V D +A I+++EG+L G SSGAA + KK +
Sbjct: 250 PSIMDKELIDDVITVTDDEALQWMSRIVREEGILAGISSGAAACGTEKYIKKYDV-RDST 308
Query: 302 VVVILPDGIRNYMT 315
+V + PD Y++
Sbjct: 309 IVTVFPDTGERYLS 322
>UniRef50_Q7VK29 Cluster: Cysteine synthase; n=13; Bacteria|Rep:
Cysteine synthase - Helicobacter hepaticus
Length = 313
Score = 155 bits (377), Expect = 2e-36
Identities = 101/321 (31%), Positives = 163/321 (50%), Gaps = 21/321 (6%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
+Y + LE IG TPL+ L + + +FAK EF NP G IKDR++ + + ++ G+
Sbjct: 2 LYRSSLELIGHTPLLELTHL--NIANNNRIFAKLEFYNPAGGIKDRVALYICQKLKEKGL 59
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
+ IE T+GNTG+G+A G ++ PDK S EK + LGA+V+ TP
Sbjct: 60 LHKDSVIIEATAGNTGLGIAFVAQHFGCKAILIVPDKFSIEKQILMRALGAQVINTPKEK 119
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI---LALVPD------ 182
+ + + A+ L P A+S +Q++N NP+ HY TA+EI +A V
Sbjct: 120 GMQGA---MDRAQEMLSCTPYALSLNQFENLDNPQAHYLTTAKEIYDDMAKVQANSENGS 176
Query: 183 ---VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGD 239
+D + +K++ + V DP GS+I G G +EGIG +
Sbjct: 177 DALIDYLVCGAGSGGSFSGIVGYLKKQDSRIKGVLCDPVGSII-GGGEEGCANIEGIGNN 235
Query: 240 FVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAG 299
F+P +D S+ID V+K D +A+ R + K EG+L G SSGA +I+ ++ A ++
Sbjct: 236 FIPHTMDISLIDSVQKITDEEAYEGVRMLAKNEGILAGISSGACLIACLKLANEVQ---N 292
Query: 300 KRVVVILPDGIRNYMTKFVCD 320
+V + D + Y ++ + D
Sbjct: 293 SLIVTLFADDLSRYFSRNLID 313
>UniRef50_Q1GGP4 Cluster: Cysteine synthase; n=110; cellular
organisms|Rep: Cysteine synthase - Silicibacter sp.
(strain TM1040)
Length = 394
Score = 155 bits (376), Expect = 2e-36
Identities = 108/326 (33%), Positives = 170/326 (52%), Gaps = 19/326 (5%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
RI ++ + +G TPL+RLN++ ++ G CE+ K EF+NPG S+KDR + ++ +A G
Sbjct: 52 RIARDLADAVGHTPLIRLNKVSEETG--CEILGKAEFLNPGQSVKDRAALYIIKDAIARG 109
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
K G +E T+GNTGIG+AL A GF IV P+ S+EK + L GA++VQ PA
Sbjct: 110 ELKPGGTIVEGTAGNTGIGLALVGASMGFKTVIVIPETQSEEKKDMLRLAGAQLVQVPA- 168
Query: 131 APWESSEHFLSVAKRRLLE----DPN-AISCDQYKNDVNPRTHYEYTAEEILALV-PDVD 184
AP+++ +++ ++R E +PN AI +Q+ N N + H E T EI VD
Sbjct: 169 APYKNPNNYVRYSERLANELAKTEPNGAIWANQFDNVANRQAHVETTGPEIWEQTGGKVD 228
Query: 185 MIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF-----GEGPAD-LYFVEGIGG 238
A+ ++ K K I DP G+ ++ GE ++ EGIG
Sbjct: 229 GFICAVGSGGTLAGIAEALQPKGVK--IGLADPNGAALYSYYTTGELKSEGSSITEGIGQ 286
Query: 239 DFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGA 298
+ L+ D + D +A +++ +EGL+ GGSSG + A+R AK+L G
Sbjct: 287 GRITKNLEGLTPDFNYQIPDAEALPYVFDLLHEEGLVLGGSSGVNIAGAVRLAKEL--GP 344
Query: 299 GKRVVVILPDGIRNYMTKFVCDQWME 324
G +V IL D Y +K ++++
Sbjct: 345 GHTIVTILCDYGTRYQSKLFNPEFLK 370
>UniRef50_Q9HQ70 Cluster: Cysteine synthase; n=5;
Halobacteriaceae|Rep: Cysteine synthase - Halobacterium
salinarium (Halobacterium halobium)
Length = 327
Score = 154 bits (374), Expect = 4e-36
Identities = 102/283 (36%), Positives = 150/283 (53%), Gaps = 14/283 (4%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
++IL+ IG TPLVRL P+ + AK E NP GS KDR + MVL A+++G +
Sbjct: 3 DSILDAIG-TPLVRLTA-PEG----ATIAAKLEGFNPAGSAKDRPAREMVLAAERAGEIQ 56
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPW 133
G + +E TSGNTGIG+AL A G+ TIV P S E+ + GA++ A
Sbjct: 57 PGDQLVEATSGNTGIGLALTAAARGYDLTIVMPASMSTERKQLLRAYGADLELVDA---- 112
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP--DVDMIXXXXX 191
E VA R+ D A Q++N NPR HY TAEEIL V ++D +
Sbjct: 113 -GMETANQVAD-RVAADTGAFRVGQFENPANPRAHYRTTAEEILDQVEGREIDALVAGVG 170
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVID 251
A +++E P+ +V V+P+ + + G + +G+G FV D LD+ +ID
Sbjct: 171 TGGTITGTATRLREAHPEMSVVAVEPEANAVLSTGESGDDDFQGMGPGFVSDNLDRELID 230
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKL 294
VE A +R + ++EG+L G SSGAA ++A R A+++
Sbjct: 231 TVETVAVDAAEAETRRLAREEGVLVGQSSGAAALAATRTAERI 273
>UniRef50_Q4JSP4 Cluster: Cystathionine beta-synthase; n=3;
Actinomycetales|Rep: Cystathionine beta-synthase -
Corynebacterium jeikeium (strain K411)
Length = 381
Score = 153 bits (371), Expect = 9e-36
Identities = 108/331 (32%), Positives = 172/331 (51%), Gaps = 16/331 (4%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
R+ I + IG+TP + L R G + K + NP GS+K R++ MV A+++G
Sbjct: 31 RVSTKICDLIGNTPALELCRT----GTGSRLILKLDCFNPTGSVKIRMAMEMVQGAERAG 86
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV--VQTP 128
+ + G+R +EPTSGNTG+G+A+A + G+ T V + +K+ + LGAE+ V +P
Sbjct: 87 LLRPGSRIVEPTSGNTGLGLAIAASQRGYRFTAVVDHHAAKDKLDAMRALGAELIFVGSP 146
Query: 129 AMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIX 187
+ S+ S+AK + DPNA DQ+ N NP Y A E+ A D VD++
Sbjct: 147 DTSK-PSTVARRSMAKHIVESDPNAWWPDQHNNPDNP-GGYAQLAHELSAQCSDGVDVLV 204
Query: 188 XXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIG--GDF-VPDV 244
++++ + V V+P+GS+IFG GPA Y G G G F +
Sbjct: 205 AAVGTGGTLCGTTRELRRMGHEAKTVGVEPEGSIIFG-GPAGSYKQSGAGAPGGFTIGQN 263
Query: 245 LDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVV 304
+D ++ID+ K D AF SR + ++ GL+ GG++GAA+ ++ + A VVV
Sbjct: 264 VDYALIDQQIKVGDVKAFATSRVLARRHGLMVGGTAGAAVHEGLQTLQ--TCAANSTVVV 321
Query: 305 ILPDGIRNYMTKFVCDQWMEAH-LFKEPPER 334
++ D Y+ D W+++H L E ER
Sbjct: 322 LVCDAGEKYLDTVFNDAWLDSHGLRSEIAER 352
>UniRef50_UPI00006CB05C Cluster: Pyridoxal-phosphate dependent
enzyme family protein; n=1; Tetrahymena thermophila
SB210|Rep: Pyridoxal-phosphate dependent enzyme family
protein - Tetrahymena thermophila SB210
Length = 340
Score = 153 bits (370), Expect = 1e-35
Identities = 96/329 (29%), Positives = 158/329 (48%), Gaps = 10/329 (3%)
Query: 9 RNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQK 68
R R + I + IG+T L+ L +I +++ K E++NP GSIKDRI+ + A+
Sbjct: 2 RQRNGDTIEQMIGNTGLIELKKINPYREKGIKIYVKAEYMNPTGSIKDRIAKYIFDTAES 61
Query: 69 SGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
G + G + +SGNT VA A G+ C ++T K S EK GAEV+ P
Sbjct: 62 EGKLRKGMTVVAASSGNTACSVAFIAAQRGYKCKVITNTKCSKEKQDAPKAFGAEVIVGP 121
Query: 129 AMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIX 187
+ +S +H++++A +P+ DQY N +NP +Y EI ++D
Sbjct: 122 SNVSADSPDHYMNMATNMCKANPDYYDIDQYDNPLNPLAYYNSLGPEIWNQTSGNIDYFV 181
Query: 188 XXXXXXXXXXXXAQKVKEKCP-KCIIVTVDPQGSLIFGEGPA------DLYFVEGIGGDF 240
++ +KE + V DP GS+ + + VEG+G D
Sbjct: 182 AAGSTGGTISGTSKYLKEVSEGRVQTVLADPYGSVFYQYWKTRELITPGKFQVEGVGKDT 241
Query: 241 VPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGK 300
+P +D +ID+ + +D AF ++ K EGL+ GGSSG + +A++ A L+ A
Sbjct: 242 IPLAMDIDLIDQCVQMDDKTAFETCYKLTKFEGLMVGGSSGLNVAAALKLASTLDGPA-- 299
Query: 301 RVVVILPDGIRNYMTKFVCDQWMEAHLFK 329
+V + PD Y++K W+E + F+
Sbjct: 300 TIVTVCPDAGVKYLSKIYSQAWLEQNGFE 328
>UniRef50_Q4LEC7 Cluster: O-acetyl-L-serine sulfhydrylase; n=1;
uncultured crenarchaeote 10-H-08|Rep: O-acetyl-L-serine
sulfhydrylase - uncultured crenarchaeote 10-H-08
Length = 342
Score = 153 bits (370), Expect = 1e-35
Identities = 97/307 (31%), Positives = 152/307 (49%), Gaps = 6/307 (1%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
R +IL+ IG+TPL+RL I K +G+E E++AK EF NP GS+KDRI M+ +A + G
Sbjct: 2 RTGEDILDLIGNTPLLRLRHIEKQHGVEAEIWAKLEFYNPSGSLKDRIYREMITKAIERG 61
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
+ G +E ++GN GI G+ TIV P+ S+E+ I G +V TP
Sbjct: 62 DLRPGMEILEVSTGNAGIACTFVGTHLGYRVTIVMPEGMSEERKQLIKAFGGNLVFTPGA 121
Query: 131 APWESSEHFLSVAKRRLLEDPNAI-SCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXX 188
+ L A+ + ++P +Q+ N N + H + T EI VD
Sbjct: 122 E--SDVDLSLRKAEEMMRQNPGKYWFPNQFTNPDNIQAHIKTTGPEIWEQTKGKVDAFVM 179
Query: 189 XXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKS 248
+ +KEK P I TV+P + I EG + +EGIG F+P LD
Sbjct: 180 SQGSGGTVSGVGKFLKEKNPSVKIYTVEPSEAPIISEGRWGSHKIEGIGDGFIPRNLDLG 239
Query: 249 VIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPD 308
V D V ++ M+R++ + EG+ G SSG + +A++ AKK +++V ++ D
Sbjct: 240 VCDGVVTTTSDESIAMARQLARLEGIFGGISSGCNVAAAVKVAKK--HPNLRKIVTLICD 297
Query: 309 GIRNYMT 315
Y++
Sbjct: 298 SGNRYLS 304
>UniRef50_Q5KNK5 Cluster: Cysteine synthase; n=1; Filobasidiella
neoformans|Rep: Cysteine synthase - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 398
Score = 152 bits (368), Expect = 2e-35
Identities = 80/181 (44%), Positives = 113/181 (62%), Gaps = 4/181 (2%)
Query: 1 MSNSRSFTRNR---IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDR 57
MSNS + ++ + ++ L+ +G TPL+RL+RI + G +C + KCEF + GGS+KDR
Sbjct: 1 MSNSATQPQHHWHGVLSSALDAVGHTPLIRLDRIAAEEGFKCNLLGKCEFFSAGGSVKDR 60
Query: 58 ISYTMVLEAQKSGIAKSGTRF-IEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMST 116
I+ M+ A+KSG G IEPTSGNTGIG+ALA A+ G+ C I P K S EK
Sbjct: 61 IAKRMIEHAEKSGQLIPGKSIVIEPTSGNTGIGLALACALKGYKCIITLPAKMSLEKEVM 120
Query: 117 ISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI 176
+ LGAE+V+TP A ++S E + VA+ P+++ DQY N NP +HY T EEI
Sbjct: 121 LKALGAEIVRTPTEAAFDSPESHIGVARTLQQAIPDSVILDQYSNPNNPLSHYFGTYEEI 180
Query: 177 L 177
+
Sbjct: 181 M 181
Score = 91.5 bits (217), Expect = 4e-17
Identities = 50/118 (42%), Positives = 73/118 (61%), Gaps = 8/118 (6%)
Query: 206 KCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKS--VIDKVEKPNDYDAFN 263
K + +I+ VDP GS++ G P + Y VEGIG DF PDVLD+ +ID+ K D ++F
Sbjct: 240 KASRTLILAVDPVGSILGGGEPGN-YEVEGIGYDFFPDVLDREPQLIDEWLKTTDDESFE 298
Query: 264 MSREIIKKEGLLCGGSSGAAMISAI-----RAAKKLNFGAGKRVVVILPDGIRNYMTK 316
++ +IK+EGL GGSSG+A A+ A + + VV++ PDG+RNYM+K
Sbjct: 299 ATKRLIKREGLFVGGSSGSAFAGALYYLQSPAGRHIAEDPEANVVILFPDGVRNYMSK 356
>UniRef50_Q8YXP3 Cluster: Cysteine synthase; n=2; Nostoc sp. PCC
7120|Rep: Cysteine synthase - Anabaena sp. (strain PCC
7120)
Length = 365
Score = 151 bits (366), Expect = 4e-35
Identities = 102/331 (30%), Positives = 162/331 (48%), Gaps = 8/331 (2%)
Query: 2 SNSRSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYT 61
S + S +N ++ + +G+ P+V+L I + E F K E NPGGSIK++ +
Sbjct: 18 SGNHSKWKNTTATDVTQALGNVPIVKLRNISPVCAI-AECFLKLESCNPGGSIKEKNAVY 76
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
+V A++ G+ G IE +SGN G+G+A+ AV G+ IV K + G
Sbjct: 77 LVTCAEEEGLLVPGGTIIESSSGNFGVGLAMVGAVRGYRVIIVVDAKTPPPFRRMLKAYG 136
Query: 122 AEVVQTPAMAPWES---SEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA 178
AE+V P ES + + AK P+A Q+ N +N H YTA EI A
Sbjct: 137 AELVDVPLHEADESGSMQKARMKRAKELAATIPDAWYPCQHLNPLNTEAHSYYTAREIEA 196
Query: 179 -LVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIG 237
++D + A+ ++ + PK I+ VD GS+I G A Y + GIG
Sbjct: 197 HFADELDAVVVGVSTAGQIMGIARYLRPRFPKIRIIGVDVVGSVIMGTS-AKPYKMTGIG 255
Query: 238 GDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFG 297
F P LD S++D+ + A+++ + ++EGLL G S+GA + + A++L G
Sbjct: 256 LSFFPPNLDLSLLDRAYIVPEDLAYSVCHALARREGLLLGASTGAIVAGGLHLAREL--G 313
Query: 298 AGKRVVVILPDGIRNYMTKFVCDQWMEAHLF 328
G R+++I PD Y+ +W+E H F
Sbjct: 314 RGARILMINPDRGDRYLETVYDSEWLERHGF 344
>UniRef50_Q014R8 Cluster: Cysteine synthase; n=3; Ostreococcus|Rep:
Cysteine synthase - Ostreococcus tauri
Length = 908
Score = 151 bits (366), Expect = 4e-35
Identities = 95/337 (28%), Positives = 163/337 (48%), Gaps = 18/337 (5%)
Query: 8 TRNRIYNNIL---ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVL 64
T RI N + + IG TP++ L+ + + +++ KCE++NP GSIKDRI+ ++
Sbjct: 121 THARIANGAVVPQQLIGGTPMIDLSEFSANP--KVKIYGKCEYMNPSGSIKDRIAQEILT 178
Query: 65 EAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
A ++G K G + TSGNTG +A+A A+ GF ++T K S EK+ + G +V
Sbjct: 179 RALETGELKPGMTVVAATSGNTGAAIAMACAIRGFDYIVITNKKTSKEKIDAMKAYGGQV 238
Query: 125 VQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-V 183
+ + P + +H+ ++ ++PN +QY N N + + EI + V
Sbjct: 239 IVAESGVPADHPDHYQNIETTMCAQNPNYYGVNQYDNPYNADAYEKTLGPEIWSQTKGAV 298
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF----GEGP-----ADLYFVE 234
+ +K P I+ DP+GS+++ + P A + VE
Sbjct: 299 THFIAGGSTGGTITGTGRYLKSVDPTIKIMLADPKGSVLWDYFVNDVPEEDLVAKSWEVE 358
Query: 235 GIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKL 294
G+G D +P VL ID K D +F + R + + G+L GGSSG + +A + ++
Sbjct: 359 GVGKDSIPGVLQTEYIDGAVKGCDASSFRICRMVAESSGILLGGSSGLNLHAARVLSSQI 418
Query: 295 NFGAGKRVVVILPDGIRNYMTKFVCDQWMEAHLFKEP 331
G +V +L D Y++K D+W+E+ +P
Sbjct: 419 KEGV---IVTVLCDSGVKYLSKIFNDEWLESKNLNQP 452
>UniRef50_A3ERN7 Cluster: Cysteine synthase; n=3; Bacteria|Rep:
Cysteine synthase - Leptospirillum sp. Group II UBA
Length = 312
Score = 151 bits (365), Expect = 5e-35
Identities = 98/299 (32%), Positives = 151/299 (50%), Gaps = 8/299 (2%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR 77
+ IG TPLV L + + GL+ ++ K E N GGS+KDR + MV +A+++G G R
Sbjct: 14 QLIGRTPLVALESMTR--GLDRVVWVKLESRNLGGSVKDRPARYMVEQAERNGELAPGGR 71
Query: 78 FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE 137
+E TSGNTGI +A + G+ IV P+ S E++ + LGAEV TPA +
Sbjct: 72 IVEATSGNTGIALAQIGVLKGYPVVIVMPEGVSQERVYHLKALGAEVELTPAR---DGMA 128
Query: 138 HFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDV-DMIXXXXXXXXXX 196
+ A+ L E P + Q++N NP +HY T EIL + + D
Sbjct: 129 GAIRRAETLLSERPGSFMPRQFENPANPESHYRTTGPEILDQLGRLPDGFVAGIGTGGTI 188
Query: 197 XXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKP 256
+ ++E+ I ++P S + + ++GIG FVP +LD+SV DK+E
Sbjct: 189 TGVGRFLRERHEAVRIWGLEPASSAVLSGSSPGPHRIQGIGAGFVPKILDRSVCDKIEPI 248
Query: 257 NDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
+D A R + ++EG++ G SSGA + A+ A+ L G VV I+ D Y +
Sbjct: 249 DDRTAIETMRRLTREEGIMAGISSGANVAGALLLARTL--PPGSHVVTIVCDSYERYFS 305
>UniRef50_Q44004 Cluster: Cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O- acetylserine
(Thiol)-lyase); n=18; Bacteria|Rep: Cysteine synthase
(EC 2.5.1.47) (O-acetylserine sulfhydrylase) (O-
acetylserine (Thiol)-lyase) - Ralstonia metallidurans
(strain CH34 / ATCC 43123 / DSM 2839)
Length = 341
Score = 149 bits (360), Expect = 2e-34
Identities = 100/317 (31%), Positives = 161/317 (50%), Gaps = 10/317 (3%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYG-LECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
+ N+I+E+IG+TPLV+L R+ +G + E+FAK E +NP GS+KDR + +V + G
Sbjct: 2 VCNSIIESIGNTPLVQLRRL---FGRADAEVFAKLELLNPAGSVKDRPARYIVEKGLTEG 58
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
+ IE +SGN I +A+ + G T V K S + + GA + Q A
Sbjct: 59 AIGPHSHVIESSSGNLAIALAMICGLKGLRFTAVVDPKISPTNLKILRCYGAGIEQVTAK 118
Query: 131 -APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA-LVPDVDMIXX 188
+ E + ++ L E +AI +QY N +N +HY A EILA L D++
Sbjct: 119 DSQGGYLETRIERVRQMLREQRDAIWINQYANPLNWESHYYGEAAEILAQLAQPADVLVL 178
Query: 189 XXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKS 248
A+++++ P +V VD GS++FG+ P+ + GIG VP++L +
Sbjct: 179 GVSTSGTVHGIARRLRKAWPSMRVVGVDAVGSVLFGQ-PSQARELPGIGASRVPELLCRD 237
Query: 249 VIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGA--AMISAIRAAKKLNFGAGKRVVVIL 306
ID+V +DY A R ++ +EG+ GGSSGA A I + A ++ R++ +
Sbjct: 238 EIDEVIHIDDYTAATACRRLLAREGIFAGGSSGAVVAAIEQVLHATPVSH-RPLRILTLF 296
Query: 307 PDGIRNYMTKFVCDQWM 323
PD Y+ D W+
Sbjct: 297 PDRGERYLDTVYDDAWL 313
>UniRef50_Q9PF47 Cluster: Cysteine synthase; n=14;
Gammaproteobacteria|Rep: Cysteine synthase - Xylella
fastidiosa
Length = 332
Score = 148 bits (358), Expect = 3e-34
Identities = 97/312 (31%), Positives = 153/312 (49%), Gaps = 12/312 (3%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
IYN IL+TIG TP+V+LNRI + +++ K E NP GS+KDR++ ++L+A++ G+
Sbjct: 16 IYNTILDTIGHTPVVKLNRIAPAH---VDLYIKVESFNPSGSVKDRLALAIILDAEQQGL 72
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K G +E TSGNTG+ +A+ A G+ + S E+ + GA+V+ TPA
Sbjct: 73 LKPGDTIVEATSGNTGVALAMIAAARGYTFVATMVETFSIERRKLMRAYGAKVILTPAA- 131
Query: 132 PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD--VDMIXXX 189
E + AK L E Q+ N NP H TA EIL +D
Sbjct: 132 --ERGSGMVRKAK-ELAEQHGWFLASQFSNPANPAYHRNTTAAEILRDFAGRRLDHFVSG 188
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
+ +K P I +P + + + ++G DFVP+VL++SV
Sbjct: 189 WGTGGTLTGVGEVLKIARPDITITASEPASAALLQGKEWQPHKIQGWTPDFVPEVLNRSV 248
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPD- 308
+ D DA ++R + +EG+ G S GA + +A++ A++ GA ++ +LPD
Sbjct: 249 PHHILSVTDDDAITVARRLAAEEGVFSGISGGATVATALQIAQQAQPGA--VILAMLPDT 306
Query: 309 GIRNYMTKFVCD 320
G R + T D
Sbjct: 307 GERYFSTPLFAD 318
>UniRef50_Q4Q159 Cluster: Cysteine synthase, putative; n=4; cellular
organisms|Rep: Cysteine synthase, putative - Leishmania
major
Length = 333
Score = 147 bits (356), Expect = 6e-34
Identities = 94/312 (30%), Positives = 160/312 (51%), Gaps = 10/312 (3%)
Query: 7 FTRNR-IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLE 65
F ++R + +I + IG TP + LN++ + ++ K E NP S+KDR+ + + +
Sbjct: 5 FDKSRNVAQSIDQLIGQTPALYLNKLNNT---KAKVVLKMECENPMASVKDRLGFAIYDK 61
Query: 66 AQKSGIAKSGTRFI-EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
A+K G G + E +SGNTG+ +A A+ G+ I P+ S E+ + + GAEV
Sbjct: 62 AEKEGKLIPGKSVVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFGAEV 121
Query: 125 VQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DV 183
+ TPA + + +++AK+ + +PNA+ DQ+ N H E T EI +V
Sbjct: 122 ILTPAALGMKGA---VTMAKKIVTANPNAVLADQFATKYNALIHEETTGPEIWEQTNHNV 178
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPD 243
D A+ +K+ IV V+P S + G + ++GIG FVPD
Sbjct: 179 DCFIAGVGTGGTLTGVARALKKMGSHARIVAVEPMESPVLSGGKPGAHKIQGIGPGFVPD 238
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVV 303
VLD+S+ID+V DA + ++ + +G+ CG S GA + +A++ A++ GK +V
Sbjct: 239 VLDRSLIDEVFCVAGDDAIETALKLTRSDGVFCGFSGGANVYAALKIAERPEM-EGKTIV 297
Query: 304 VILPDGIRNYMT 315
I+P Y++
Sbjct: 298 TIIPSFGERYLS 309
>UniRef50_A1S012 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Thermofilum pendens Hrk 5|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Thermofilum pendens (strain Hrk 5)
Length = 296
Score = 147 bits (355), Expect = 8e-34
Identities = 96/298 (32%), Positives = 153/298 (51%), Gaps = 18/298 (6%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR 77
E +G TP++ L+ P +++ K E+ NP GS KDRI+ M+ A + G+ + G
Sbjct: 8 ELVGKTPVLELDVPPG------KVYVKLEYTNPTGSHKDRIAVYMLRSAVEEGVLRPGGS 61
Query: 78 FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE 137
F+E +SGNT + +A A + GF I D S K+ + +GAEV P PW +
Sbjct: 62 FVEASSGNTAVSLAWAGVLAGFKPIIFAEDTISKGKLGLLLGMGAEVHLVP-RKPWGDPD 120
Query: 138 HFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXX 197
H+++ AK R E+ +QY N+ N R HYE T E+L+ VD
Sbjct: 121 HYVNAAK-RFAEENGLPFLNQYGNEANWRAHYETTGPELLSQTGGVDAFVMGIGTGGTVI 179
Query: 198 XXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDK--SVIDKVEK 255
+ +KE+ P+ +V V P+GS I G D +EG+ FVP++ ++ V+D VE+
Sbjct: 180 GIGKYLKERVPEARVVGVVPKGSPIAGGRLGD--NIEGLASTFVPELYERHGRVVDSVEE 237
Query: 256 PNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNY 313
+ DA + ++++ + G+L G S+GA+ A R A + G RV +I D + Y
Sbjct: 238 VSLADALSSLKDLL-RAGVLAGPSTGASFHVARRLASR-----GLRVAIIAADSVLRY 289
>UniRef50_Q5V5J3 Cluster: Cysteine synthase; n=1; Haloarcula
marismortui|Rep: Cysteine synthase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 330
Score = 146 bits (354), Expect = 1e-33
Identities = 96/303 (31%), Positives = 152/303 (50%), Gaps = 16/303 (5%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
++ + IGDTPLV L+ + + K E NP S+KDRI+ MV A +SG
Sbjct: 37 SVTDLIGDTPLVCLDSFAGN------LLGKVEAANPY-SVKDRIALYMVEAAAESGDLTD 89
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
+E TSGNTGIG+A A G+ C + P+ S+E+ +S LGA++ TPA
Sbjct: 90 DGMVVEATSGNTGIGLAAVCAARGYDCVLTMPESMSEERRQLLSGLGADLELTPADGGMS 149
Query: 135 SSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXXXX 193
+ L + P + Q++N+ NPR H E T EI A DVD +
Sbjct: 150 GAIE----RANELADAPGTVRARQFENEANPRAHRETTGPEIWADTDGDVDAVVAGVGTG 205
Query: 194 XXXXXXAQKVKEKCPKCII-VTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDK 252
++ +KE+ + V V+P+ S + D + ++GIG FVPD+L + +ID+
Sbjct: 206 GTITGISEYIKERVGADLTSVAVEPEQSKLLSAADPDSHDIQGIGPGFVPDILRRDLIDE 265
Query: 253 VEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRN 312
V + ++ S+ + + G++ G SSGAA+ +A A + + VVV+LPD
Sbjct: 266 VRTASKAESVAASQRLASQAGIMVGISSGAALHAAAEYATE---HPEETVVVVLPDTGER 322
Query: 313 YMT 315
Y++
Sbjct: 323 YLS 325
>UniRef50_Q018U5 Cluster: COG0031: Cysteine synthase; n=5; cellular
organisms|Rep: COG0031: Cysteine synthase - Ostreococcus
tauri
Length = 440
Score = 145 bits (352), Expect = 2e-33
Identities = 101/328 (30%), Positives = 165/328 (50%), Gaps = 33/328 (10%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
RIY NILET+GDTP++++NR+ + G+E M+ K E+ NP S+KDR++ ++ +A++ G
Sbjct: 85 RIYENILETVGDTPVIKINRLAPE-GVE--MYVKAEYFNPLSSVKDRLAVAVITDAERRG 141
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
+ K G +E TSGNTGI VA+A A G+ C I + S E+ + +LGA+V+ TP
Sbjct: 142 LLKPGDTVVEATSGNTGIAVAMACAQRGYRCVICMAEPFSVERRKIMRMLGAKVIVTP-- 199
Query: 131 APWESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILA--LVPDVDMIX 187
++ + VAK L + C Q++N+ NP H T EI+ +D
Sbjct: 200 ---KAGKGTGMVAKAEELAAKHGWFLCRQFENEANPAYHASTTGPEIVRDFAGKKLDYFV 256
Query: 188 XXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEG----------PAD------LY 231
++ ++E P IV ++P+ + + G PA +
Sbjct: 257 TGYGTGGTFQGVSRVLRESRPDTKIVLLEPEAAALVSSGIKTERKDTGAPAGSHPAFAAH 316
Query: 232 FVEGIGGDFVPDVLDK----SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISA 287
V+G DF+P VL+ ++ D++ K DA ++ + + EG+ G S GA A
Sbjct: 317 PVQGWTPDFIPLVLENGLNMNLYDELVKIEGGDAVQTAQALARNEGIFTGISGGATFAGA 376
Query: 288 IRAAKKLNFGAGKRVVVILPDGIRNYMT 315
+ AKK G ++ +LPD YM+
Sbjct: 377 LTVAKKA--PKGSVILAMLPDTSERYMS 402
>UniRef50_A7Q973 Cluster: Chromosome chr19 scaffold_66, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr19 scaffold_66, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 373
Score = 145 bits (351), Expect = 2e-33
Identities = 95/332 (28%), Positives = 157/332 (47%), Gaps = 16/332 (4%)
Query: 5 RSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVL 64
+ ++ + ++E IG+TPL+R+N + + G CE+ K EF+NPGGS+KDR++ ++
Sbjct: 33 KPISKKKPRRGLIEAIGNTPLIRINSLSEATG--CEILGKAEFLNPGGSVKDRVAVKIIE 90
Query: 65 EAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
EA +SG G E ++G+T I +A G C +V PD + EK + LGA V
Sbjct: 91 EALESGQLAPGGVVTEGSAGSTAISLATVAPAYGCKCHVVIPDDVAIEKSQILEALGATV 150
Query: 125 VQTPAMAPWESSEHFLSVAKRRLLED-PNAISCDQYKNDVNPRTHYEYTAEEILALVP-D 182
+ ++ +H+++ + DQ++N N R HYE T EI D
Sbjct: 151 ERVRPVS-ITHKDHYVNKQNSVFSSNCKGGFFADQFENLANFRAHYEGTGPEIWEQTSGD 209
Query: 183 VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG--------EGPADLYFVE 234
+ ++ ++EK P +DP GS +F + P D E
Sbjct: 210 LHAFVAAAGTGGTLAGVSRSLQEKSPNIKCFLIDPPGSGLFNKITRGVILKNPFDT-ITE 268
Query: 235 GIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKL 294
GIG + + + +D D +A MSR ++K +GL G SS + A+R A+ +
Sbjct: 269 GIGINRLTQNFLMAELDGAFHGTDMEAVEMSRYLLKNDGLFVGSSSAMNCVGAVRVAQSI 328
Query: 295 NFGAGKRVVVILPDGIRNYMTKFVCDQWMEAH 326
G G +V IL D +++KF Q++ H
Sbjct: 329 --GPGHTIVTILCDSGMRHLSKFYDSQYLSQH 358
>UniRef50_Q016B2 Cluster: Cysteine synthase; n=2; Ostreococcus|Rep:
Cysteine synthase - Ostreococcus tauri
Length = 415
Score = 144 bits (348), Expect = 5e-33
Identities = 110/343 (32%), Positives = 170/343 (49%), Gaps = 38/343 (11%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
++L IG+TPLVR+ + C+++AKCEF+NPGGS+KDR++ +V EA +SG
Sbjct: 52 DVLRAIGNTPLVRVESLSAI--TRCDVYAKCEFLNPGGSVKDRVARRIVEEALESGELVE 109
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
G E T+G+TG+ +A+ G C + PD + EK + + GA VV+ ++
Sbjct: 110 GGVVCEGTAGSTGVSLAMVCRALGVECFVAMPDDAAMEKSALVEAYGARVVRVRPVS-IA 168
Query: 135 SSEHFLSVAKRRLLEDPNA-------ISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMI 186
+HF++VA+R+ E A DQ++N N R H E T EI + D +D
Sbjct: 169 HRDHFVNVARRK-AESARASHGAGAGFFADQFENLANYRAHKEGTGVEIYDELGDALDAF 227
Query: 187 XXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF-------------GEG-----PA 228
+ EK P I DPQGS +F EG P
Sbjct: 228 VCACGTGGTLAGVGAALLEKNPAVKIFLADPQGSGLFNRVVRGVMYTQEEAEGKRLKNPF 287
Query: 229 DLYFVEGIGGDFVPD----VLDKS-VIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAA 283
D EG+G + + + +L++S ++ K +D +A MSR + K +GL G SS
Sbjct: 288 DT-VTEGVGINRITENFKIMLERSNMLAGAIKVSDVEAVAMSRFVAKHDGLFIGSSSAVN 346
Query: 284 MISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKFVCDQWMEAH 326
+++A+R A+ L G G RV I D +MTKF ++++ AH
Sbjct: 347 LVAAVRVAQSL--GPGHRVCTIACDSGLRHMTKFWSNEYLAAH 387
>UniRef50_A3UA05 Cluster: Cysteine synthase; n=1; Croceibacter
atlanticus HTCC2559|Rep: Cysteine synthase -
Croceibacter atlanticus HTCC2559
Length = 325
Score = 142 bits (345), Expect = 1e-32
Identities = 99/324 (30%), Positives = 151/324 (46%), Gaps = 13/324 (4%)
Query: 8 TRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQ 67
T + +Y +IL TIG TPLV+L ++ + G + ++ K E NPGGSIKDR S ++ E
Sbjct: 10 TNHTVYESILTTIGHTPLVKLKKLSAELGFQ--VYGKLEMTNPGGSIKDRTSLNIIEEEI 67
Query: 68 KSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT 127
G T +E +SGN IG+A + IV K + T+ +L A V+
Sbjct: 68 AKGNITKNTTLVESSSGNMAIGLAQVCSYHNIPLVIVVDPKANKH---TLKILDAYGVKV 124
Query: 128 PAMAPWESSEHFLSVAKRRLLE----DPNAISCDQYKNDVNPRTHYEYTAEEILALVPDV 183
+ + +L +R+ E PNAI +QY N NP+ H++ T +EI +PDV
Sbjct: 125 DMVEKASQNGGYLGARLQRVQELVAQLPNAIWTNQYGNKANPKAHWQ-TMKEIYEDLPDV 183
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPD 243
D + A + + ++ VD +GS+IFGE P + + + G G
Sbjct: 184 DYVFSATSTCGTLMGCADFINSEHLNTKLIAVDAKGSVIFGEQPEERH-IPGHGAGLPSQ 242
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVV 303
LDK+ I V D + +++K E +L GGSSG A+ +AI K V
Sbjct: 243 FLDKNAIHDVVHTTDKECVTGCHKLLKLESILAGGSSG-AVTTAIEKLKH-KIPKHSTCV 300
Query: 304 VILPDGIRNYMTKFVCDQWMEAHL 327
+IL D Y+ W+ L
Sbjct: 301 LILCDRGERYIDTIYNKDWVAQKL 324
>UniRef50_A7D2W0 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: Pyridoxal-5'-phosphate-dependent enzyme, beta
subunit - Halorubrum lacusprofundi ATCC 49239
Length = 339
Score = 141 bits (342), Expect = 3e-32
Identities = 103/323 (31%), Positives = 153/323 (47%), Gaps = 20/323 (6%)
Query: 8 TRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQ 67
T +++LETIG+TPLVR++ P ++AK E NPG SIKDRI M+
Sbjct: 16 THREPLSSVLETIGETPLVRVHDSPD----AVPVYAKLESFNPGASIKDRIGKYMLERML 71
Query: 68 KSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT 127
+ G G +EPT+GNTGIG+A+A G V P++ S EK + LGAEVV T
Sbjct: 72 ERGDVGEGGTVVEPTAGNTGIGLAVAAKQLGLNAVFVVPERFSVEKQQLMRALGAEVVNT 131
Query: 128 PAMAPWESSEHFLSVAKRRLLED-PNAISCDQYKNDVNPRTHYEYTAEEI-LALVPDVDM 185
P+ E F + ++ +A+ Q+ N +N HYE TA EI AL +V
Sbjct: 132 PS----EDGMGFAIDRAHEIADELDDAVVPQQFSNPLNAEAHYETTAPEIDEALDGEVGA 187
Query: 186 IXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSL---IFGEGPA-DLYFVEGIGGDFV 241
+ A+ +E+ P +V V+P GS GE A + Y EGIG +
Sbjct: 188 VVAGCGTGGTLMGMARYFRERDPDTYVVAVEPAGSAYREFLGEEVAHEEYKTEGIGTHDI 247
Query: 242 P--DVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFG-- 297
++ D +++D ++ D + + +EG L S+ A I+A R A+ + G
Sbjct: 248 DTNELFDPALVDDIQAVPDREVHEEMGRLAAEEGQLVASSAAANAIAAKRVARAIRDGEI 307
Query: 298 --AGKRVVVILPDGIRNYMTKFV 318
V PD Y++K V
Sbjct: 308 DAPYDTVATAFPDSSERYLSKGV 330
>UniRef50_Q934D2 Cluster: Cysteine synthase; n=1; Streptomyces
avermitilis|Rep: Cysteine synthase - Streptomyces
avermitilis
Length = 327
Score = 140 bits (338), Expect = 9e-32
Identities = 106/333 (31%), Positives = 158/333 (47%), Gaps = 20/333 (6%)
Query: 10 NRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
++ + IL T+G+TPLV L R+ D+G +F K E NPGGSIKDR + M+L +S
Sbjct: 3 DKTFPGILSTVGNTPLVELERLLPDFG--SRVFGKIERFNPGGSIKDRSALGMLLAGIRS 60
Query: 70 GIAKSG-TRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
G + G T IE +SGN +G+A G V K +++ ++ +S AEV
Sbjct: 61 GEVQPGRTVIIESSSGNLAVGLAQICRYFGLRFICVVDGKTTEQNLAILSAFRAEVEVVT 120
Query: 129 AMAPWESSEHFLSVAKRRLLE----DPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDV 183
E + FL V RR+ E P+A +QY + +NP+ H E T EI +L V
Sbjct: 121 ERD--ELTGEFLPVRLRRVRELVAATPDAYWPNQYASLLNPKAH-ETTMREIEESLDGAV 177
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPD 243
D + ++ + IV VD GS IFG + G G VP
Sbjct: 178 DFLFCSVSTFGTLRGCRDHIRARGLDTTIVAVDALGSAIFGLESTQR-LIPGHGASVVPP 236
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVV 303
++D S D+V +D + R +I +E +L GGSSGA + + + ++ G V
Sbjct: 237 LMDASAADEVVHISDLECVVACRRLIGREAVLAGGSSGATVAALWKIRHRI--PEGSNCV 294
Query: 304 VILPDGIRNYMTKFVCDQWME------AHLFKE 330
+I PDG Y+ D W+ AHL+K+
Sbjct: 295 LIFPDGGDRYLDTIYSDAWVNQNFGDVAHLWKD 327
>UniRef50_P45040 Cluster: Cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O- acetylserine
(Thiol)-lyase); n=115; cellular organisms|Rep: Cysteine
synthase (EC 2.5.1.47) (O-acetylserine sulfhydrylase)
(O- acetylserine (Thiol)-lyase) - Haemophilus influenzae
Length = 316
Score = 140 bits (338), Expect = 9e-32
Identities = 102/313 (32%), Positives = 155/313 (49%), Gaps = 17/313 (5%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
IY + +IG+TPLVRL K +G + K E NP S+K RI MV +A+K G
Sbjct: 3 IYADNSYSIGNTPLVRL----KHFGHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGT 58
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
G ++ TSGNTGI +A A G+ T+ P+ S E+ + LG +V T
Sbjct: 59 LTKGKEIVDATSGNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAK 118
Query: 132 PWESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXX 189
+ + ++ A+ + DP+ + Q++N NP+ H E T EI VD++
Sbjct: 119 GMKGA---IAKAEEIVASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAG 175
Query: 190 XXXXXXXXXXAQKVKEKCPKCII-VTVDPQGSLIFGEGPA------DLYFVEGIGGDFVP 242
++ +K K I V V+P S + + A + ++GIG F+P
Sbjct: 176 VGTGGSITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIP 235
Query: 243 DVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRV 302
LD S+ID+VE + A +R ++ +EG+L G SSGAA+ +A R AK F A K +
Sbjct: 236 KNLDLSIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEF-ADKLI 294
Query: 303 VVILPDGIRNYMT 315
VVILP Y++
Sbjct: 295 VVILPSASERYLS 307
>UniRef50_Q88B28 Cluster: Cysteine synthase; n=1; Pseudomonas
syringae pv. tomato|Rep: Cysteine synthase - Pseudomonas
syringae pv. tomato
Length = 372
Score = 139 bits (337), Expect = 1e-31
Identities = 93/315 (29%), Positives = 152/315 (48%), Gaps = 8/315 (2%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
N+++ I TPL+ L RI K+ + + K E NPGGSIKDR + ++ EA+K G K
Sbjct: 7 NVIDGISKTPLIDLARINKE--ISTNVIVKLEKYNPGGSIKDRAAAYIIREAEKKGQLKP 64
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
G IE +SGN I +A+ AV G+ + K ++ + + GAEV+
Sbjct: 65 GGTIIESSSGNFAISLAMIGAVSGYKVIALVDPKATETNKALMKAYGAEVITVTEKDDTG 124
Query: 135 S-SEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXXX 192
S + + +A + P + DQ N ++ HY TA+EI ++ +
Sbjct: 125 SYHKTRIKLANDLAKKIPGSYRPDQCFNVLSSLAHYNSTAKEIHEQTSGNIAGVVCAVST 184
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVP-DVLDKSVID 251
++ K+ P + VD GS +FG GP+ Y + G+G + P ++ D + ID
Sbjct: 185 GGQIGGVSEYFKDHLPDVKVTCVDAYGSAVFG-GPSHAYKIPGVGLGWTPRNINDTTKID 243
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
+ D A+ +R + + EG+L G SSGA +++A+ + L+ G K +V IL D
Sbjct: 244 YFYRAKDESAYIAARLLCRHEGILVGVSSGAVLLAALNLS--LHLGNQKPIVAILGDSGE 301
Query: 312 NYMTKFVCDQWMEAH 326
Y+ D W+ H
Sbjct: 302 RYLDTLYNDDWLNEH 316
>UniRef50_P63874 Cluster: Cysteine synthase B (EC 2.5.1.47)
(O-acetylserine sulfhydrylase B) (O- acetylserine
(Thiol)-lyase B); n=27; Actinomycetales|Rep: Cysteine
synthase B (EC 2.5.1.47) (O-acetylserine sulfhydrylase
B) (O- acetylserine (Thiol)-lyase B) - Mycobacterium
bovis
Length = 323
Score = 139 bits (337), Expect = 1e-31
Identities = 88/309 (28%), Positives = 153/309 (49%), Gaps = 16/309 (5%)
Query: 13 YNNILETIGDTPLVRLNRIPKDY-----GLECEMFAKCEFVNPGGSIKDRISYTMVLEAQ 67
Y+++L+ +G+TPLV L R+ + G ++AK E NP GSIKDR + M+ +A+
Sbjct: 4 YDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAE 63
Query: 68 KSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT 127
G+ + G +EPTSGNTGI +A+A + G+ V P+ S E+ + L GA+++ +
Sbjct: 64 ADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFS 123
Query: 128 PAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIX 187
A S ++ AK +P+ + QY N N +HY T E+LA +P++
Sbjct: 124 AAEG---GSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLPEITHFV 180
Query: 188 XXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDK 247
+ ++E IV +P+ +GEG +Y + + FVP++ D
Sbjct: 181 AGLGTTGTLMGTGRFLREHVANVKIVAAEPR----YGEG---VYALRNMDEGFVPELYDP 233
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIR-AAKKLNFGAGKRVVVIL 306
++ DA +RE++ EG+ G S+GA + +A+ A L G + +++
Sbjct: 234 EILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVV 293
Query: 307 PDGIRNYMT 315
D Y++
Sbjct: 294 ADAGWKYLS 302
>UniRef50_Q6L2R6 Cluster: Cysteine synthase; n=5; cellular
organisms|Rep: Cysteine synthase - Picrophilus torridus
Length = 316
Score = 138 bits (335), Expect = 2e-31
Identities = 100/313 (31%), Positives = 151/313 (48%), Gaps = 14/313 (4%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I N+L IG+TPLV+LN+I E++ K E+ +PG SIKDRI+ M+ +A++ G+
Sbjct: 4 IKENVLNAIGNTPLVKLNKINVK---NIEIYVKLEYYSPGMSIKDRIALGMIEDAERKGL 60
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVV---QTP 128
+ G I TSGNTGIG+A+A AV G+ V NS E+ + LGAEVV Q P
Sbjct: 61 IEPGDTIIGKTSGNTGIGLAIACAVKGYRFVAVMSAGNSAERQKILRALGAEVVLVPQQP 120
Query: 129 AMAPWESSEHFLSVAKRR---LLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VD 184
P S +++ L E NA +QY N +N + H T +EI+ +D
Sbjct: 121 GEEPGRISRKDNDAVEKKTQELTEKLNAYRPNQYINSMNWKVHQHTTGQEIIRQTSGRLD 180
Query: 185 MIXXXXXXXXXXXXXAQKVK--EKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVP 242
A+ +K KC V D L + + ++G G P
Sbjct: 181 AFVAYIGTGGTFVGIARALKSFNNDIKCYPVEPDVAAFLAGKKVITTQHLIQGGGHAVKP 240
Query: 243 DVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRV 302
D+S++D + ++ +A +R + K EG+L G S GA + +A + L G V
Sbjct: 241 PFWDESIVDGYIQVSEDEAIKTARALAKNEGILTGFSGGANVAAAAKLDDSLR--PGSIV 298
Query: 303 VVILPDGIRNYMT 315
V +LPD Y++
Sbjct: 299 VTVLPDTGLKYLS 311
>UniRef50_Q216V8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=3; Proteobacteria|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Rhodopseudomonas palustris (strain BisB18)
Length = 304
Score = 138 bits (334), Expect = 3e-31
Identities = 92/310 (29%), Positives = 156/310 (50%), Gaps = 12/310 (3%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I +++L+ IG+TP+VRL + K++G++ K E NPGGS K R++ M+ +A+ GI
Sbjct: 2 INDSVLDLIGNTPVVRLCALSKEFGIDA--LIKLESFNPGGSHKVRVAKAMIEDAEARGI 59
Query: 72 AK--SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
SG IEP+ GNTGIG+AL G+ +V PD S EK + L GAEVV + +
Sbjct: 60 LTRGSGQTIIEPSGGNTGIGLALVGCQLGYKLILVIPDNYSQEKQELLRLHGAEVVLSDS 119
Query: 130 MAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD--VDMIX 187
+ +A L P + +Q +N NP H TA EILA + +D+
Sbjct: 120 R---RGNNSHGEMAMEIQLMHPEYVMLNQQRNPANPEVHRRTTAREILADFGEQRIDVFV 176
Query: 188 XXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDK 247
++ +K + P+ V+P+ + + A + ++G+ VP VL+
Sbjct: 177 GGIGTGGHITGISETLKARWPEMKAYGVEPEQCDLLNDRHAP-HDIQGLSVGIVPAVLNL 235
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
++D + K D M++ +++E + G SS A +++ + A L+ G V+ +
Sbjct: 236 GILDGMIKVAKADCIEMAKTTLRRESISLGISSAANLVAISKIAGDLD--RGSTVLTLSY 293
Query: 308 DGIRNYMTKF 317
D I +Y++ F
Sbjct: 294 DTIDSYLSYF 303
>UniRef50_P55708 Cluster: Putative cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O-acetylserine
(Thiol)-lyase); n=8; Proteobacteria|Rep: Putative
cysteine synthase (EC 2.5.1.47) (O-acetylserine
sulfhydrylase) (O-acetylserine (Thiol)-lyase) -
Rhizobium sp. (strain NGR234)
Length = 336
Score = 138 bits (334), Expect = 3e-31
Identities = 101/333 (30%), Positives = 161/333 (48%), Gaps = 28/333 (8%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
++ + + IG TP++ ++ +P G + K E NPGGS+KDR++ +MV+ A + G
Sbjct: 2 LHTTVTQLIGQTPVMSID-VP---GRNATLVLKIEKNNPGGSMKDRMARSMVIAALQDGR 57
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
G +E +SGNTG G+ALA G V + +K+ + LGAE+
Sbjct: 58 LPPGGTIVESSSGNTGTGLALAALEFGLRFIAVVDHHAAPDKIRMMRALGAEI----RYV 113
Query: 132 PWESSEHFLSVAKRRLL------EDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VD 184
+ E ++V +R+ L + P A+ +Q N NP Y +E++A +PD +D
Sbjct: 114 EGDFREDEVAVVERQRLAAQLGAQLPGALFMNQSDNPANPE-GYTGLVDELVAQLPDGID 172
Query: 185 MIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIG---GDFV 241
+Q++K P + V+P GS++FG+ P Y+ G G GD V
Sbjct: 173 AFVGCVGTGGSMTGISQRLKRNNPAVRTIAVEPAGSIVFGK-PGHPYYQSGTGTPAGDEV 231
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGK- 300
VLD ID+ + D AF +R I +++GLL GGS+G A+ A+ GAGK
Sbjct: 232 GKVLDYGCIDEGVQVTDTQAFETARYIARRKGLLVGGSTGGAIYKALEF-----IGAGKL 286
Query: 301 --RVVVILPDGIRNYMTKFVCDQWMEAHLFKEP 331
VV + DG Y+ ++WM +P
Sbjct: 287 TGTVVTTVADGGEKYLGTIFDEEWMAKRRLLDP 319
>UniRef50_P29848 Cluster: Cysteine synthase B (EC 2.5.1.47)
(O-acetylserine sulfhydrylase B) (O- acetylserine
(Thiol)-lyase B); n=194; cellular organisms|Rep:
Cysteine synthase B (EC 2.5.1.47) (O-acetylserine
sulfhydrylase B) (O- acetylserine (Thiol)-lyase B) -
Salmonella typhimurium
Length = 303
Score = 138 bits (333), Expect = 4e-31
Identities = 96/304 (31%), Positives = 152/304 (50%), Gaps = 19/304 (6%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
N + +TIG+TPLV+L R+ D G E++ K E NP GS+KDR + +M++EA+K G K
Sbjct: 2 NTLEQTIGNTPLVKLQRLGPDNG--SEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIK 59
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPW 133
G IE TSGNTGI +A+ A+ G+ ++ PD S E+ + + GAE++
Sbjct: 60 PGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGM 119
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXX 192
E + L++A + E DQ+ N NP HY T EI +
Sbjct: 120 EGARD-LALA---MSERGEGKLLDQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGT 175
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDP-QGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVID 251
++ ++E+ IV + P +GS I G + +++P + + S++D
Sbjct: 176 TGTITGVSRFLREQEKPVTIVGLQPEEGSSIPG--------IRRWPAEYMPGIFNASLVD 227
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
+V + DA N RE+ +EG+ CG SSG A+ A+R A+ G VV I+ D
Sbjct: 228 EVLDIHQNDAENTMRELAVREGIFCGVSSGGAVAGALRVARAT---PGAIVVAIICDRGD 284
Query: 312 NYMT 315
Y++
Sbjct: 285 RYLS 288
>UniRef50_Q5QVH4 Cluster: Cysteine synthase; n=6;
Gammaproteobacteria|Rep: Cysteine synthase - Idiomarina
loihiensis
Length = 350
Score = 137 bits (331), Expect = 6e-31
Identities = 98/323 (30%), Positives = 154/323 (47%), Gaps = 12/323 (3%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR 77
+ IG T L+R+ + G C++F KCEF NPGGSIKDR + ++ +A + G K G
Sbjct: 9 DLIGQTDLLRIPSLSDLTG--CDIFIKCEFQNPGGSIKDRAAKQLIDDAMERGELKPGMT 66
Query: 78 FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE 137
+E T+GNTGIG+A+ G V P+ + EK I L G E++ + P+++
Sbjct: 67 VVEGTAGNTGIGLAVVAKSYGLRMLAVMPNDQTPEKERMIRLHGGELMAVDPV-PFKNEN 125
Query: 138 HFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXX 196
HF A+R E + +Q++N N R HY +T EI +D +
Sbjct: 126 HFYHTARRLAEERDDCWWANQFENTSNARAHYLHTGPEIWEQTEGRIDALVSVAGTGGTI 185
Query: 197 XXXAQKVKEKCPKCIIVTVDPQGSLIF-----GEGPAD-LYFVEGIGGDFVPDVLDKSVI 250
++ +KE+ P+ + VDP GS I+ GE ++ EGIG + D ++ I
Sbjct: 186 GGNSRFLKEQNPELDVWVVDPDGSGIYEFLRSGEYVSNGGSMTEGIGIMRLVDNFRQARI 245
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
D D D +SR I ++G++ G SS + A+ AA L G G R+V D
Sbjct: 246 DHAVNLPDQDLVTLSRYIRDEDGIVLGSSSALNVAGALAAA--LRKGPGHRIVTFSCDLG 303
Query: 311 RNYMTKFVCDQWMEAHLFKEPPE 333
++K +++ PE
Sbjct: 304 ERSVSKLYNPEYLRGRGLNPDPE 326
>UniRef50_O67507 Cluster: Cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O- acetylserine
(Thiol)-lyase); n=7; Bacteria|Rep: Cysteine synthase (EC
2.5.1.47) (O-acetylserine sulfhydrylase) (O-
acetylserine (Thiol)-lyase) - Aquifex aeolicus
Length = 327
Score = 137 bits (331), Expect = 6e-31
Identities = 92/304 (30%), Positives = 150/304 (49%), Gaps = 13/304 (4%)
Query: 16 ILETIGDTPLVRLNR-IPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
IL+ +G+TPLVR+ + +P+D + E++AK E NPGGS+KDR + +M L+A K G+ K
Sbjct: 25 ILKLVGNTPLVRVKKCLPEDIPEDVEIWAKLESFNPGGSVKDRPALSMFLDALKRGLIKE 84
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
G I+ TSGNTGI +A+ A G + P S+E+ I GA++ T P E
Sbjct: 85 GKVVIDATSGNTGIALAMVGAALGVPVELAMPANVSEERKKIIKAFGAKLYLTD---PLE 141
Query: 135 SSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXX 192
++ + + + + P + DQY N N + H+ T EI +
Sbjct: 142 GTDGAILFVRELVQKYPEKYVYLDQYNNPANWKAHFYSTGIEIWNQTKGRITHFVAGIGT 201
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDK 252
+++K P ++ V P EG ++ I P + D++ +D+
Sbjct: 202 GGTIMGTGRRLKIYNPNIQVIGVQPAYPFHGIEG------LKHIESSIKPGIFDETFLDR 255
Query: 253 VEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVV-ILPDGIR 311
DA+ +RE+ KK+ + G SSGAA+ + I+ A++L K V+V + PDG
Sbjct: 256 TIFVETEDAYYWARELAKKDAIFVGQSSGAALWACIQLARELAKKGEKGVIVTVFPDGGE 315
Query: 312 NYMT 315
Y+T
Sbjct: 316 KYLT 319
>UniRef50_A2R5Q4 Cluster: Catalytic activity: O3-acetyl-L-serine +
hydrogen sulfide = L-cysteine + acetate; n=4; cellular
organisms|Rep: Catalytic activity: O3-acetyl-L-serine +
hydrogen sulfide = L-cysteine + acetate - Aspergillus
niger
Length = 318
Score = 136 bits (330), Expect = 8e-31
Identities = 95/301 (31%), Positives = 158/301 (52%), Gaps = 16/301 (5%)
Query: 14 NNILETIGDTPLVRLNRI-PKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
++ L+ IG+TP V+L R+ P+D +F K E +NP GS KDR++ +++ EA++
Sbjct: 8 DSALDAIGNTPCVQLTRVVPQDCA---RVFIKLESLNPTGSYKDRMALSVIEEAERRNDL 64
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
+ G +E T G+TG +A AV G+ +V+ D + EK++T++ GA + P+
Sbjct: 65 RPGMTVVEATGGSTGSSLAFVCAVKGYTFRVVSSDAFAKEKLNTMTAFGAHLDIVPSENG 124
Query: 133 WESSEHFLSV---AKRRLLEDPNAIS---CDQYKN-DVNPRTHYEYTAEEILALVPD-VD 184
+ + S+ A+R ED + S DQ+ N DV P YE EILA V + +D
Sbjct: 125 KITPQLIPSMRERARRIATEDKDPSSYYYADQFSNPDVFP--GYETLGREILAQVGEPID 182
Query: 185 MIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDV 244
+ +K+ P C + ++P + +G + VEGIG F P +
Sbjct: 183 AFCGAVGGAGMVMGVGKTLKQSWPACHVAVLEPASAPALTKGHGGEHSVEGIGIGFPPPL 242
Query: 245 LDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVV 304
L+K D+ ++ + +M R + ++EGLL G SSG +++AI+ AK+L G GK VV
Sbjct: 243 LNKDWYDEARAIDEREGRSMCRRLAREEGLLVGTSSGLNVVAAIQLAKEL--GPGKTVVT 300
Query: 305 I 305
+
Sbjct: 301 V 301
>UniRef50_Q0LP40 Cluster: Cysteine synthase; n=3; Bacteria|Rep:
Cysteine synthase - Herpetosiphon aurantiacus ATCC 23779
Length = 340
Score = 136 bits (328), Expect = 1e-30
Identities = 96/326 (29%), Positives = 154/326 (47%), Gaps = 9/326 (2%)
Query: 4 SRSFTR-NRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTM 62
+ FT+ R ++ I++ IG+TPL+ L RI ++ ++ +FAK E NPGGS+KDR++ ++
Sbjct: 3 THGFTKLARSHDGIVQLIGNTPLIPLRRIFAEHPIQ--LFAKLEMFNPGGSVKDRVARSI 60
Query: 63 VLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGA 122
+ +A G T IE +SGN GIG+A G + + +++ + + GA
Sbjct: 61 ITKALAEGRIDQATTIIESSSGNLGIGLAQVCRYFGLRFICIVDSRTTNQNIQILRAYGA 120
Query: 123 EVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD 182
EV P + V + PN+ C+QY N NP HY T EILA +P+
Sbjct: 121 EVEIITQPDPDLLTARIKRVHALQ-ASIPNSFWCNQYANLHNPMAHYA-TMSEILASLPN 178
Query: 183 V-DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFV 241
V D + A+ ++E+ ++ VD GS+IFG P + G G +
Sbjct: 179 VPDYLFCATSSCGTLRGCAEYIREQGLATKVIAVDALGSVIFGGQPGQ-RLIPGHGASRI 237
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
P++ + V +D D ++ +E + GGSSG +I AI A + A
Sbjct: 238 PELFQPDLAAGVVYVSDADCVAGCHSLLDQEAIFAGGSSG-GVIRAI-AQMLPSMPANAT 295
Query: 302 VVVILPDGIRNYMTKFVCDQWMEAHL 327
V IL D Y+ W++ HL
Sbjct: 296 CVAILCDRGERYLDTVFNHAWIDQHL 321
>UniRef50_O16284 Cluster: Cysteine synthase; n=4;
Caenorhabditis|Rep: Cysteine synthase - Caenorhabditis
elegans
Length = 337
Score = 135 bits (326), Expect = 2e-30
Identities = 89/300 (29%), Positives = 146/300 (48%), Gaps = 8/300 (2%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG-IAKSGT 76
+T+G+TPLV L I K GL+ + K E++NP S+KDRI+ TMV +A+K+G I T
Sbjct: 12 DTVGNTPLVLLRNITK--GLDARIAVKIEYLNPSCSVKDRIAKTMVDDAEKAGKIVPGKT 69
Query: 77 RFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESS 136
+E TSGN GI +A + G+ +V S E+ + + GAEV+ + P E
Sbjct: 70 VLVEGTSGNLGIALAHIGRIRGYKVILVMTTAMSIERRAMLRAYGAEVILSD---PAEGH 126
Query: 137 EHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXX 195
+ + + + P+A DQ+ N NP HY T EI VDM+
Sbjct: 127 PGIVKKIEMLVSKLPDAYCLDQFSNPSNPAAHYRTTGPEIWKQTQGKVDMVCFGVGSGGT 186
Query: 196 XXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEK 255
+ ++ + + V+P S + P + + GIG +P +D+S+ +V +
Sbjct: 187 VTGVGRYLRAQKQNIGVYPVEPFESSVLSGFPRGPHKIHGIGAGLIPGNVDRSLFTEVFR 246
Query: 256 PNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
DA M+R + +E +L G SSGA +++A+ A++ GK +V + Y +
Sbjct: 247 VKSEDAMKMARRLADEEAILGGISSGANVVAAVELARRPE-NIGKLIVTTVNSFAERYFS 305
>UniRef50_A3UUR9 Cluster: Probable cysteine synthase A; n=1; Vibrio
splendidus 12B01|Rep: Probable cysteine synthase A -
Vibrio splendidus 12B01
Length = 303
Score = 134 bits (324), Expect = 4e-30
Identities = 97/305 (31%), Positives = 156/305 (51%), Gaps = 20/305 (6%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
IG+TP+++L++ L +++ K EF+NP GSIKDR + +MV SG + T +
Sbjct: 7 IGNTPIIKLDKTSNS--LYADIYVKLEFLNPWGSIKDRAAKSMVEAGIASGKITNTTILV 64
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHF 139
E T+GNTGI +A A G IV P+ S+E+ +++LGA+V+ T S+EH
Sbjct: 65 EATTGNTGISLAGICASMGLELIIVMPEYVSEERKKLLTMLGAKVILT-------STEHN 117
Query: 140 L--SVAK-RRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDV-DMIXXXXXXXXX 195
+V+K L + PN DQ N NP H + T EI+ D
Sbjct: 118 YAGAVSKANELAKQPNHFLVDQGNNPANPLAH-QQTGREIIDFFDGTPDFFIAGIGTGGH 176
Query: 196 XXXXAQKVKEKCPKCIIVTVDP-QGSLIFGEGPADL----YFVEGIGGDFVPDVLDKSVI 250
+K+ +V ++P Q +++ G+ P + + + GIG + +D+SVI
Sbjct: 177 CNGIGNTLKQHNKHVKVVAIEPVQAAVLSGKTPTNKINSDHGILGIGPGIIASTVDQSVI 236
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
D V +++ A ++REIIK EGLL G SSGA++ AI A++ GK+++ I
Sbjct: 237 DDVFVIDEHMAKQVTREIIKNEGLLLGFSSGASIACAIEYAQRPE-NEGKKILTIAASQS 295
Query: 311 RNYMT 315
Y++
Sbjct: 296 ERYLS 300
>UniRef50_A0Z0S2 Cluster: Cysteine synthase; n=1; marine gamma
proteobacterium HTCC2080|Rep: Cysteine synthase - marine
gamma proteobacterium HTCC2080
Length = 336
Score = 134 bits (323), Expect = 6e-30
Identities = 107/331 (32%), Positives = 153/331 (46%), Gaps = 14/331 (4%)
Query: 10 NRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
N I + +L+ IGDTP+V L KD ++AK E NPGGS+KDR + M+ A++
Sbjct: 2 NAICSTVLDAIGDTPMVSLAAFGKD--TLPHLYAKLECTNPGGSMKDRAAKGMIEWAERE 59
Query: 70 GIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
SG R + TSGN G+G+A+ AV G+ + K + + + +LGAEV++
Sbjct: 60 HNLTSGARIVVCTSGNMGVGMAMVCAVKGYQLMCLVDAKINPATENCLRVLGAEVIKV-Y 118
Query: 130 MAPWESSEHFLSVAK--RRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMI 186
H ++K L E P+AI DQY + +H T EI A V I
Sbjct: 119 QRDETGGYHLTRLSKLDSVLAEYPDAIYLDQYDSPAAVMSHSTSTGPEIYNAFQGQVRAI 178
Query: 187 XXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF-GEGPADLYFVEGIGGDFVPDVL 245
A+ KE P+ I VD GSL G G A + G+G P
Sbjct: 179 VMVAGTGGSSMGIARFFKEHSPQTDIWLVDEAGSLALPGNGGASPRHLNGMGTSIAPANY 238
Query: 246 D----KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
+ ID V N D+ + E+ + EG+L GGS GAA + +R ++GA
Sbjct: 239 GPADFHTFIDHVVYVNAEDSIRAAIELARCEGILVGGSGGAA-VQVMRDVAAAHYGADDN 297
Query: 302 VVVILPD-GIRNYMTKFVCDQWMEAHLFKEP 331
+V +LPD G R T+F D W+ A P
Sbjct: 298 LVALLPDHGSRYTETQFDPD-WLAARGINVP 327
>UniRef50_A7HK96 Cluster: Pyridoxal-5'-phosphate-dependent protein
beta subunit; n=2; Thermotogaceae|Rep:
Pyridoxal-5'-phosphate-dependent protein beta subunit -
Fervidobacterium nodosum Rt17-B1
Length = 294
Score = 132 bits (320), Expect = 1e-29
Identities = 97/298 (32%), Positives = 149/298 (50%), Gaps = 21/298 (7%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
IG TPL+ +++ YG+ +AK E NP GS+KDR Y M+ +A KSG T F+
Sbjct: 13 IGKTPLIYIDK----YGI----YAKFERNNPIGSVKDRPVYFMIRDAIKSGKINENTVFV 64
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHF 139
EPTSGNTGI +A A G + P+ S E+M+ + LGA+++ M ++ E
Sbjct: 65 EPTSGNTGIALAWLGARLGLKVILTMPESVSVERMNMLKALGADLILVENMT--KAVEKA 122
Query: 140 LSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXXXX 198
L + R PN Q++N N H T EIL + VD
Sbjct: 123 LEIVSERSAFMPN-----QFENPANSLAHEITTGPEILEEMNFLVDAFVAGVGTGGTITG 177
Query: 199 XAQKVKEKCPKCI-IVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPN 257
+ +K + + + ++P S + G + + ++GI FVP +LD+ +ID+++
Sbjct: 178 VGRVLKRLLKENVKVCALEPLQSPVLTNGISGKHRIQGIAPGFVPKILDRQLIDEIKLIV 237
Query: 258 DYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
D +A NM + I+ KEGL G SS A ++ AI +K F +RVV I PD Y++
Sbjct: 238 DEEALNMMK-ILWKEGLFVGVSSAANLLGAIYIKEKYKF---ERVVTIFPDDGTKYLS 291
>UniRef50_Q8KNS8 Cluster: Pyridoxal-phosphate dependent enzyme; n=1;
Bacillus thuringiensis serovar israelensis|Rep:
Pyridoxal-phosphate dependent enzyme - Bacillus
thuringiensis subsp. israelensis
Length = 346
Score = 131 bits (317), Expect = 3e-29
Identities = 94/306 (30%), Positives = 145/306 (47%), Gaps = 12/306 (3%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
NI++ IG+TPLV+L D +FAK E +NP G +KDR + ++LEA+K+G+ K
Sbjct: 6 NIVDAIGNTPLVQLQL---DSSARGNVFAKLEMLNPFG-MKDRAAKKVILEAKKNGVLKD 61
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGA--EVVQTPAMAP 132
G IE +SG +G+A+ G IVT + ++ + LG E+V
Sbjct: 62 GAPIIESSSGTMALGLAMVGTYLGHPVHIVTDKRTDQMTLAKLKSLGCKLEIVTEMTHLG 121
Query: 133 WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXX 192
W+S+ L + L E+ A QY+N NP YE A+E L + +D++
Sbjct: 122 WQSAR--LDRLEEILKENKEAFCPRQYENSDNPNA-YESLADEALEELGHIDILVASVGS 178
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDK 252
A+ +K+ P +V VD GS+IF + G G +P +D S+ID+
Sbjct: 179 GGSLCGTARALKKANPDLRVVAVDAVGSVIFNQPDIPGRLQGGHGNSVIPKNVDFSIIDE 238
Query: 253 VEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPD-GIR 311
V ND + + + E+ K E L G SS A+ A+ ++ I PD G R
Sbjct: 239 VHWLNDEECYAANLELAKCEKLFAGNSSAASY--AVSRFLSSRCSEETNILTIFPDRGDR 296
Query: 312 NYMTKF 317
Y T +
Sbjct: 297 YYKTVY 302
>UniRef50_Q747V7 Cluster: Cysteine synthase B; n=11; cellular
organisms|Rep: Cysteine synthase B - Geobacter
sulfurreducens
Length = 308
Score = 130 bits (315), Expect = 5e-29
Identities = 98/300 (32%), Positives = 152/300 (50%), Gaps = 18/300 (6%)
Query: 19 TIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRF 78
+IG TPLV L + + + + AK E N GGS+KDR + M+ +A++SG
Sbjct: 11 SIGATPLVELRHLNPNPRVR--ILAKLEGNNVGGSVKDRPALYMLAKAEESGELVPEKTI 68
Query: 79 IEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEH 138
+EPTSGNTGI +A+ V G+ +V P S E+ + + GAE+V +P E+++
Sbjct: 69 LEPTSGNTGIALAMLGTVKGYRVKLVMPACVSLERRAVLEAYGAELVLSPHD---EATDG 125
Query: 139 FLSVAKRRLLEDPNAISC-DQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXX 196
+ +A R L E+P+ +QY N NP HYE TA EI VD
Sbjct: 126 AIRLAHRILEEEPDRYYMPNQYANPNNPLAHYETTAPEIFRDTGGAVDFFVAGMGTGGTL 185
Query: 197 XXXAQKVKEKCPKCIIVTVDPQ-GSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEK 255
++ +EK P IV V+P+ G + G ++ + VP + +D
Sbjct: 186 MGTSRYFREKKPSVRIVGVEPRLGHKVQG--------LKNMQEAIVPPIYHPEALDLKLT 237
Query: 256 PNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
+D AF+ +RE+ +EGL G SSGAA+ A++ A+ + AG +VV+LPD Y++
Sbjct: 238 VHDEPAFDTARELAAREGLFVGMSSGAAVAGAVQVAR--DAPAGSTIVVLLPDRGDRYLS 295
>UniRef50_Q8KB68 Cluster: Cysteine synthase/cystathionine
beta-synthase family protein; n=10; Chlorobiaceae|Rep:
Cysteine synthase/cystathionine beta-synthase family
protein - Chlorobium tepidum
Length = 456
Score = 130 bits (313), Expect = 9e-29
Identities = 90/323 (27%), Positives = 155/323 (47%), Gaps = 13/323 (4%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
N+I + +TPLV + ++ + AK E+++P S R+S +V +A++ G
Sbjct: 3 NDIFDISDNTPLVLMKQLTRQK--RARFMAKLEYMSPCFSHYCRVSGAIVRDAEERGAIH 60
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPW 133
G ++ T G +GI +A+A G+ + P+ EK + LGAE+V TP+ A
Sbjct: 61 PGMTLVDWTFGTSGIALAMAAVSRGYKVLLAAPESICREKQEVLRALGAELVLTPSEALP 120
Query: 134 ESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXXX 192
+ + VA+ + PNA + Y+N V+ + H + T EI V +
Sbjct: 121 GDLQSCVDVAENLVRTLPNAWFANMYQNPVSRQVHQDGTGPEIFRQTEGKVTHLFVPMAS 180
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG-------EGPADLYFVEGIGGDFVPDVL 245
+ K P+ I+ V+P+GS ++G +G + +E IG
Sbjct: 181 GAMISGIGRYFKSVNPEVQIIGVEPEGS-VYGDLHGGKSQGTPSAFQLEDIGAVRPTSFW 239
Query: 246 DKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVI 305
D +VID++ + +D DAFN RE+++ E + GG+SGAAM +A+R + +G VVV+
Sbjct: 240 DPNVIDRIVQVSDADAFNCGRELLRAEAVFAGGASGAAMAAALREGEA--YGDDALVVVM 297
Query: 306 LPDGIRNYMTKFVCDQWMEAHLF 328
+ D +++ D WM F
Sbjct: 298 MTDFGGYDLSRMYNDDWMRRQGF 320
>UniRef50_A4M0Z4 Cluster: Cysteine synthase; n=2; Bacteria|Rep:
Cysteine synthase - Geobacter bemidjiensis Bem
Length = 360
Score = 129 bits (311), Expect = 2e-28
Identities = 96/304 (31%), Positives = 149/304 (49%), Gaps = 19/304 (6%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
++L++IG TP+ + + K+ + + AK E NPGGS+KDR + M+L A+ SG
Sbjct: 5 SLLDSIGGTPVAEIYSLCKNPAVR--IVAKLEGNNPGGSVKDRPARQMILAAEASGELTP 62
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
+EPTSGNTGI +A+ A G+ +V P S E+ S + GAE+V +P E
Sbjct: 63 DKVILEPTSGNTGIALAMIAAARGYRIKLVMPACVSVERRSVLEAYGAEIVLSPGC---E 119
Query: 135 SSEHFLSVAKRRLLEDP-NAISCDQYKNDVNPRTHYEYTAEEILALV-PDVDMIXXXXXX 192
+++ + +A + L EDP +QY N N HY+ T EI +V +
Sbjct: 120 ATDGAIRLAHKILAEDPAKYYMPNQYANPNNVLAHYKTTGPEIWHQTGGEVTHVVAGMGT 179
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQ-GSLIFGEGPADLYFVEGIGGDFVPDVLDKSVID 251
A KE P +V V+P G I G ++ + VP + D +
Sbjct: 180 SGTLMGLASYFKEVKPSVQVVGVEPTLGHKIQG--------LKNMKEAIVPPIYDCAAYH 231
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
+ D DAF +R + EG+ CG S GAA+ A++ A +L+ G +VVI+PD
Sbjct: 232 RNLVVEDDDAFETARLLAAHEGIFCGMSGGAAVFGALQLASELSSGV---IVVIVPDRGD 288
Query: 312 NYMT 315
Y++
Sbjct: 289 RYLS 292
>UniRef50_Q8FPS2 Cluster: Cysteine synthase; n=3;
Corynebacterium|Rep: Cysteine synthase - Corynebacterium
efficiens
Length = 343
Score = 128 bits (310), Expect = 2e-28
Identities = 105/320 (32%), Positives = 156/320 (48%), Gaps = 22/320 (6%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSG 75
I +TIG+TPLVRL+R+ +D + ++AK E+ NPGGS KDR + MV +G K G
Sbjct: 38 IADTIGNTPLVRLDRLTRDR--DFTLWAKLEYFNPGGSAKDRTAQAMV----TAGTLKPG 91
Query: 76 TRFIEPTSGNTGIGVALATAVCG---FGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
+E +SGN GI +A AV G F C +V P N + + LGA V Q P
Sbjct: 92 DMVVESSSGNLGIALA-REAVLGDWTFHC-VVDPRANR-STVKHMQALGAVVHQ--ITEP 146
Query: 133 WESSEHFLSVAKRR----LLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDV-DMIX 187
E + +L ++R L E P AI DQY N R H E T EI+ + D +
Sbjct: 147 DEETGDWLVARRKRVAQLLQEIPEAICLDQYSNTEAFRAHQEGTMAEIVQQLGHAPDHLL 206
Query: 188 XXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDK 247
+ ++ + VD GS++F P + + G G VP++ +
Sbjct: 207 VAVSTTGTIGGCLRHIEAHHLPTQVTAVDAMGSVLFDGNPGPRH-LPGFGAGMVPELSRQ 265
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
+V + D ++ +R +++KE +L G+SG A+I+A+ K + F +G VVVIL
Sbjct: 266 ITPHRVLRVADRESVEGARTLVRKETIL-PGASGGAVIAAVDKLKDV-FESGSDVVVILH 323
Query: 308 DGIRNYMTKFVCDQWMEAHL 327
D YM D W+E L
Sbjct: 324 DSGTRYMDTIYNDDWVEETL 343
>UniRef50_Q98DL3 Cluster: Cysteine synthase; n=19; cellular
organisms|Rep: Cysteine synthase - Rhizobium loti
(Mesorhizobium loti)
Length = 362
Score = 128 bits (308), Expect = 4e-28
Identities = 94/330 (28%), Positives = 157/330 (47%), Gaps = 33/330 (10%)
Query: 9 RNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQK 68
R R++++IL+T+GDTP++R+N + + ++ K EF NP S+KDR++ ++ E ++
Sbjct: 13 RGRLFDSILDTVGDTPVIRVNNLGPAHAT---VYVKAEFFNPAASVKDRLALNIIEEGER 69
Query: 69 SGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
SG K G +E TSGNTGIG+A+ A G+ + D S E+ + +LGA+VV TP
Sbjct: 70 SGALKPGQTVVEATSGNTGIGLAMVCAQKGYPLVVTMADSFSVERRKLMRMLGAKVVLTP 129
Query: 129 AMAPWESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEIL--ALVPDVDM 185
+ + F K L + N Q++ N H TA EI+ +D
Sbjct: 130 -----RAEKGFGMYKKAVELAEANGWFLARQFETAANAAIHEATTAREIINDFAGSRLDC 184
Query: 186 IXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPA----------------D 229
A+ ++ + P IV +P + + G G A +
Sbjct: 185 FVTGYGTGGTVVGVARVLRRERPDTRIVLSEPANAQLIGSGKAQQRGAHGAPAASHPAFE 244
Query: 230 LYFVEGIGGDFVPDVL----DKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMI 285
+ ++G DF+P+VL D S+ D+V + ++ + +KEG+ G S GA
Sbjct: 245 PHPIQGWTPDFIPNVLQEAIDASLYDEVMPIAGPEGIKWAKALAQKEGIFTGISGGATFA 304
Query: 286 SAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
A + A+K AG ++ +LPD YM+
Sbjct: 305 VARQVAEKA--PAGSVILCMLPDTGERYMS 332
>UniRef50_Q881D4 Cluster: Pyridoxal-phosphate dependent enzyme
family/ornithine cyclodeaminase family protein; n=2;
Pseudomonas syringae group|Rep: Pyridoxal-phosphate
dependent enzyme family/ornithine cyclodeaminase family
protein - Pseudomonas syringae pv. tomato
Length = 707
Score = 126 bits (303), Expect = 2e-27
Identities = 85/296 (28%), Positives = 136/296 (45%), Gaps = 4/296 (1%)
Query: 36 GLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATA 95
G+ + F K E +NP GSIK + + +V + Q G+ T IE +SGN G+ +A+ A
Sbjct: 27 GVGPDFFLKMESLNPAGSIKLKTAVGLVNDVQARGLLGPQTTLIESSSGNLGVALAMICA 86
Query: 96 VCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM-APWESSEHFLSVAKRRLLEDPNAI 154
G T V +S + + GA+V+Q A +++ + ++ DP +
Sbjct: 87 ERGIPFTCVVDPNSSSHNIRMMRSYGAQVIQVEIPDANGGFLGTRIALIREKVASDPRYV 146
Query: 155 SCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVT 214
+QY+N NPR H TA I VD + Q + P I+
Sbjct: 147 WLNQYENAANPRAHARTTAHSISRHFGHVDYLFVGAGTTGTLMGCLQHFQRHHPTTKIIA 206
Query: 215 VDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGL 274
VD GS+ FG PA F+ G+G P + + I +E + +A M R + + +G+
Sbjct: 207 VDSVGSVTFGT-PASRRFIPGLGTSQRPPIFNGDGIHALEMVPEANAVAMCRILARSKGM 265
Query: 275 LCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKFVCDQWMEAHLFKE 330
L GGS+ A +I+A+ A ++ G VV + PD Y+ DQW+E +E
Sbjct: 266 LVGGST-ATVIAAVHAWRE-RIEPGSVVVALSPDWGERYLDTLYDDQWVEQRFGRE 319
>UniRef50_Q48J16 Cluster: Pyridoxal-phosphate dependent enzyme
family/ornithine cyclodeaminase family protein; n=3;
Proteobacteria|Rep: Pyridoxal-phosphate dependent enzyme
family/ornithine cyclodeaminase family protein -
Pseudomonas syringae pv. phaseolicola (strain 1448A /
Race 6)
Length = 727
Score = 125 bits (302), Expect = 2e-27
Identities = 90/323 (27%), Positives = 148/323 (45%), Gaps = 16/323 (4%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
+Y+++ + + D ++++ GL + F K E +NP GSIK + + ++ + Q G+
Sbjct: 1 MYDSLCDIVHDQTFLKVS------GLGADFFLKMESLNPAGSIKLKTAVGLINDLQTRGL 54
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
T IE +SGN G+ +A+ A T V +S + + GAEV+Q A
Sbjct: 55 LGPDTILIESSSGNLGVALAMICAERAIPFTCVVDPNSSSHNVRMMRSYGAEVIQ--VQA 112
Query: 132 PWESSEHFL----SVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIX 187
P +++ FL ++ + +L DP + +QY+N NPR H TA I VD +
Sbjct: 113 P-DANGGFLGTRIALIREKLASDPRYVWLNQYENAANPRAHARTTARSISQHFGHVDYLF 171
Query: 188 XXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDK 247
Q + P I+ VD GS+ FG PA F+ G+G P +
Sbjct: 172 VGAGTTGTLMGCVQHFQRHHPSTRIIAVDSVGSVTFGT-PASRRFIPGLGTSQHPPIYKA 230
Query: 248 SVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILP 307
I +E + M R + + +GLL GGS+ A +I+A+ ++ G VV + P
Sbjct: 231 DGIYALEMVPESRTVAMCRILARSKGLLVGGST-ATVIAAVHVWRE-RIEPGSVVVALSP 288
Query: 308 DGIRNYMTKFVCDQWMEAHLFKE 330
D Y+ DQW+E +E
Sbjct: 289 DWGERYLDTLYDDQWVEQRFGRE 311
>UniRef50_A0TSM7 Cluster: Cysteine synthase; n=3; Burkholderia
cenocepacia|Rep: Cysteine synthase - Burkholderia
cenocepacia MC0-3
Length = 312
Score = 124 bits (300), Expect = 4e-27
Identities = 87/306 (28%), Positives = 148/306 (48%), Gaps = 8/306 (2%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
+IL+TIG+T LV L + G +F K E NP GS+KDRI+ M+ ++ G K
Sbjct: 7 SILDTIGNTSLVPLRHVVPKNG--ARLFVKLESQNPTGSMKDRIALAMIEAPERDGRLKP 64
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
G +E T G+TG+ +AL AV +V+ D S EK+ + LLGA++ P+ +
Sbjct: 65 GGAVVEYTGGSTGVSLALVCAVKRHPLHLVSSDAFSKEKLDHMRLLGAKLTLVPSDNGKQ 124
Query: 135 SSEHFLSVAK--RRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXX 191
+ + + + R+ + A Q +N + Y A+EI +D
Sbjct: 125 TEKLTKDMIREAHRIAGETGAYITAQMEN-TDQLDAYTKMADEIWEQTGGRLDGFVQSVG 183
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVID 251
+++++E + I V+P S + GP + ++GIG +V + + D
Sbjct: 184 TAASLRGISRRLREHDARIRIAGVEPAESAVLSGGPTGAHKIDGIGAGYVVPLWRDGIAD 243
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
++E+ + DA M+ + +EGL CG S+GA + A+R A++L G +V I+ D
Sbjct: 244 ELERVSTEDARAMAFRLAAEEGLFCGTSTGANVTGALRLAERL--GPDATIVTIMCDTGM 301
Query: 312 NYMTKF 317
Y+ F
Sbjct: 302 KYLKSF 307
>UniRef50_Q7NMK0 Cluster: Cysteine synthase; n=3; Bacteria|Rep:
Cysteine synthase - Gloeobacter violaceus
Length = 320
Score = 120 bits (290), Expect = 6e-26
Identities = 83/304 (27%), Positives = 146/304 (48%), Gaps = 14/304 (4%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
++L+ +G+TPL+RL R+ + E++ K E+ NPGGS+KDR + M+LE ++SG
Sbjct: 21 DLLQWVGNTPLLRLERVTAGLSPDVEVYGKAEWFNPGGSVKDRPALNMILEGERSGRLTR 80
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
++ TSGNTGI A A G+ + P S+E+ + G +++ T P
Sbjct: 81 EKIILDATSGNTGIAYAWIAARRGYRVKLALPLNASEERKRILKAYGVDLILTD---PTL 137
Query: 135 SSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXX 192
S+ + A+R DP DQY N+ N + HY T EI V
Sbjct: 138 GSDGAIQEARRLYAADPERYFYPDQYSNNANWQAHYLTTGVEIYQQTGGRVTHFVAGLGT 197
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDK 252
+++KE P ++ + P EG ++ + VP + + ++ D+
Sbjct: 198 SGTCMGVGRRLKEFDPAVRVIAMQPDSPFHGLEG------LKHMETAIVPAIYNPALPDR 251
Query: 253 VEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRN 312
+ + +A + + ++EG+L G S+G + +A+R A++L+ G VV IL D
Sbjct: 252 QVEVSTEEAQRTVKRLAREEGMLVGISAGGNVAAALRLARELDRGV---VVTILCDSADK 308
Query: 313 YMTK 316
Y+++
Sbjct: 309 YLSE 312
>UniRef50_Q2JV56 Cluster: Cysteine synthase; n=6; Bacteria|Rep:
Cysteine synthase - Synechococcus sp. (strain JA-3-3Ab)
(Cyanobacteria bacteriumYellowstone A-Prime)
Length = 304
Score = 120 bits (290), Expect = 6e-26
Identities = 86/302 (28%), Positives = 141/302 (46%), Gaps = 14/302 (4%)
Query: 17 LETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGT 76
+E +G TPL+RL R+ D ++ K E+ NPGGS+KDR + M+ ++ G G
Sbjct: 9 IELVGRTPLIRLRRVTADLPPSVRVYGKAEWYNPGGSVKDRPALNMIRAGEREGKLTPGK 68
Query: 77 RFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESS 136
++ TSGNTGI A A G+ + P S E+ ++ G EVV T P S
Sbjct: 69 IILDATSGNTGIAYAWIGAALGYKVKLALPANASPERKKILAAYGVEVVLTD---PALGS 125
Query: 137 EHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXXXXX 194
+ + A+ E+P+ DQY N N + HYE T EI V
Sbjct: 126 DGAIEKARALYAENPDLYFYPDQYSNPANWQAHYETTGVEIWEQTQGQVTHFVTGLGTSG 185
Query: 195 XXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVE 254
++++E I+ + P EG ++ + P++ D ++ D+
Sbjct: 186 TCMGVGRRLREYRSDIQIIAMQPDSPFHGLEG------LKHMATALKPEIYDPTLPDQHI 239
Query: 255 KPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYM 314
+ + A M + + +EGLL G S+GA +++A++ A +L+ G VV IL DG Y+
Sbjct: 240 EISTEAAQKMVKRLALEEGLLVGISAGANVVAALQVACQLSSGV---VVTILCDGADKYL 296
Query: 315 TK 316
++
Sbjct: 297 SE 298
>UniRef50_P87131 Cluster: Cysteine synthase 2 (EC 2.5.1.47)
(O-acetylserine sulfhydrylase 2) (O- acetylserine
(Thiol)-lyase 2); n=11; Ascomycota|Rep: Cysteine
synthase 2 (EC 2.5.1.47) (O-acetylserine sulfhydrylase
2) (O- acetylserine (Thiol)-lyase 2) -
Schizosaccharomyces pombe (Fission yeast)
Length = 395
Score = 120 bits (289), Expect = 8e-26
Identities = 94/341 (27%), Positives = 153/341 (44%), Gaps = 34/341 (9%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG- 70
I N + IG+T +VR+ + + G C++ AK EF+NPG S KDR++ M+ A+++G
Sbjct: 42 IVNGVEGLIGNTKMVRIKSLSQATG--CDILAKAEFLNPGNSPKDRVALQMIRTAEENGD 99
Query: 71 -IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
+ E T+G+TGI +A+ G+ I P S EK + LLGA VQ
Sbjct: 100 LVPYQSNAVYEGTAGSTGISIAMLCCSLGYDSRIYMPSDQSKEKSDILELLGAH-VQRVT 158
Query: 130 MAPWESSEHFLSVAKRRLLEDP-------NAISCDQYKNDVNPRTHYEYTAEEI-LALVP 181
AP HF++ A+R +Q++N N + H+ T EI
Sbjct: 159 PAPIVDPNHFVNTARRNAANHTVDESIPGKGYFANQFENPANWQAHFNSTGPEIWRQCAG 218
Query: 182 DVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF-------------GEGPA 228
+D ++ +K K P + DP GS ++ EG
Sbjct: 219 KLDAFIAGSGTGGTIAGISRYLKSKDPSITVCLADPPGSGLYHKVLHGVMFDLAEREGTR 278
Query: 229 DLY----FVEGIGGDFVPD--VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGA 282
+ VEG+G + + + + +ID + D A MSR ++ +GL G SS
Sbjct: 279 RRHQVDTIVEGVGINRMTRNFSIAEPLIDMAYRVTDEQAVAMSRYLVTHDGLFVGSSSAV 338
Query: 283 AMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKFVCDQWM 323
++A+R AKKL G G R+V +L D + +K ++++
Sbjct: 339 NCVAAVRLAKKL--GPGHRIVTLLCDPGSRHFSKLYNEEFL 377
>UniRef50_A3ZS86 Cluster: Cysteine synthase; n=6; Bacteria|Rep:
Cysteine synthase - Blastopirellula marina DSM 3645
Length = 388
Score = 120 bits (288), Expect = 1e-25
Identities = 97/337 (28%), Positives = 143/337 (42%), Gaps = 7/337 (2%)
Query: 2 SNSRSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYT 61
S+ S + + IL+ IG T LVR R + ++AK E NPGGS KDR +
Sbjct: 44 SSITSQKSTEVADGILQAIGRTSLVRFRRYLDRQ--DVTLYAKLESQNPGGSAKDRPARQ 101
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
M+ A K G S IE +SGN GIG+A A G V + ++ + LG
Sbjct: 102 MLEAAIKEGEISSNATIIESSSGNMGIGLAQACRYHGLRFICVVDPNAQPQNVAIMRALG 161
Query: 122 AEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP 181
AE+ + L+ R L E P + +QY N NP H + T EI L+
Sbjct: 162 AEIELVTKRVNGDFLAARLARVCRLLEEIPQSYWPNQYANPQNPIAHEQGTIREIDELLK 221
Query: 182 -DVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDF 240
+ D + ++ + +V VD GS++FG G + + G+G
Sbjct: 222 GEFDYLFVATSSTGTAQGCRNYLQSRGRDVKVVAVDAMGSVLFG-GTSGERKIPGLGAGR 280
Query: 241 VPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGK 300
P + ++ + D D R ++E LL GGSSG + + +L AGK
Sbjct: 281 EPKLARGQSFSQIVRVKDVDCVVGCRRAAEREALLVGGSSGGVLETVRFMQDEL---AGK 337
Query: 301 RVVVILPDGIRNYMTKFVCDQWMEAHLFKEPPEREFL 337
R V IL D Y+ D W++ L E E+L
Sbjct: 338 RCVAILHDSGTRYLDTVFDDAWVQETLGVSSQEIEYL 374
>UniRef50_Q9YCN5 Cluster: Cystathionine beta-synthase; n=1;
Aeropyrum pernix|Rep: Cystathionine beta-synthase -
Aeropyrum pernix
Length = 389
Score = 117 bits (282), Expect = 5e-25
Identities = 58/134 (43%), Positives = 83/134 (61%), Gaps = 1/134 (0%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLE-CEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
+Y +IL+ +G TPL+RL R+ + + LE E++ K E NPGGS+KDRI M+++A+ G
Sbjct: 9 VYGSILDLVGGTPLLRLGRVERFFRLEGVELYGKLEMFNPGGSVKDRIGLYMLMDARSRG 68
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
+ + G IEPT+GNTG+G+ALA GF V P K S EK + GA V++TP
Sbjct: 69 LVEEGAVIIEPTAGNTGVGLALAAIHYGFRLVAVMPSKMSVEKELILRAYGAYVIRTPTA 128
Query: 131 APWESSEHFLSVAK 144
P ES + VA+
Sbjct: 129 VPPESPLSYYRVAE 142
Score = 113 bits (271), Expect = 1e-23
Identities = 79/222 (35%), Positives = 109/222 (49%), Gaps = 15/222 (6%)
Query: 123 EVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI-LALVP 181
E VQT + E E S+ + + P A +QY N NPR H E T EI +
Sbjct: 165 EKVQT--LVREERVEDLRSILEASVEPTPYAYIPNQYSNPANPRAHEETTGREIWMQTGG 222
Query: 182 DVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF----GEGPADL------Y 231
VD++ A+ +K P IV VDP+GS+ G P + Y
Sbjct: 223 RVDVVYAGMGTRGTITGVARYLKRAKPSVRIVGVDPEGSIYSLVKKGMSPHEAAKHARPY 282
Query: 232 FVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAA 291
VEGIG DF+P +D S++D+V D AF+M+R + + EG+L GGSSGAA+ +A++
Sbjct: 283 KVEGIGEDFIPSTIDLSLVDEVVVVTDQQAFSMARMLARLEGVLAGGSSGAALYAAVKHI 342
Query: 292 KKLNFGAGKRVVVILPDGIRNYMTKFVCDQWMEAHLFKEPPE 333
K VVILPD RNY+ K D+WM + F E
Sbjct: 343 KTRRVRG--VAVVILPDTGRNYINKLYNDRWMGENGFSTRDE 382
>UniRef50_A0Q7G8 Cluster: Cysteine synthase; n=11; Francisella
tularensis|Rep: Cysteine synthase - Francisella
tularensis subsp. novicida (strain U112)
Length = 307
Score = 117 bits (281), Expect = 7e-25
Identities = 88/310 (28%), Positives = 141/310 (45%), Gaps = 17/310 (5%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSG 75
+L IG TP+++L ++ L +AKCE++NP GSIKDR++ ++ K+ K
Sbjct: 1 MLSLIGKTPIIKLKNTINNHNL----YAKCEWLNPTGSIKDRVAKYILENLIKNKKIKPQ 56
Query: 76 TRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWES 135
IE +SGN G +A + I P+K K I GA + +
Sbjct: 57 QAIIEASSGNMGTSLAAIGKLYKHPVYITCPEKTGQIKREMIKSFGANLTICKNTSDHTD 116
Query: 136 SEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI----LALVPDVDMIXXXXX 191
+ +++ AK +L ED + I +QY N +N HY+ T +EI L D+D
Sbjct: 117 PDFYVNKAK-QLTEDLDGILVNQYDNLLNTECHYKTTGQEIVDYFLTQNVDIDYFITVGG 175
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSL---IFGEGP-----ADLYFVEGIGGDFVPD 243
A+K+KE PK ++ DP GS+ IF G Y VEG G
Sbjct: 176 SGGTITGCAKKIKEFFPKTQVIMPDPYGSVYYDIFYHGAPIKENIHSYKVEGPGNPVFCK 235
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVV 303
+D + ID++ + +D A E+ ++G+ G SSGA A + +KL ++
Sbjct: 236 SMDLAYIDEIIQFSDNQAIQACHELASEQGIYAGHSSGANYFIAKKLLEKLPQHQSYNIL 295
Query: 304 VILPDGIRNY 313
+++ D Y
Sbjct: 296 IMVLDSGMKY 305
>UniRef50_A2BJ27 Cluster: Cysteine synthase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Cysteine synthase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 326
Score = 116 bits (280), Expect = 9e-25
Identities = 82/275 (29%), Positives = 125/275 (45%), Gaps = 17/275 (6%)
Query: 44 KCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTI 103
K E+VNP GS KDRI+ M+ A +SG G E +SGNT VA + G +
Sbjct: 42 KLEYVNPAGSHKDRIALYMIKGAIESGAVDPGGCVAEVSSGNTATSVAWIAHLLGLRSVL 101
Query: 104 VTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISC---DQYK 160
S K I + G E+V+ E S + R E+ + C DQ
Sbjct: 102 FVEKTASAVKKKLIRMFGGEIVEVTT----EGS------GRERAREEIAQMGCFFLDQMA 151
Query: 161 NDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGS 220
N++N HYE TA E+L+ V VD +++KE + V V P+GS
Sbjct: 152 NEMNHLAHYETTASELLSQVKHVDAFVMGVGTAGTVTGVGRRLKETLGNTLNVAVTPKGS 211
Query: 221 LIFGEGPADLYFVEGIGGDFVPDVLDK--SVIDKVEKPNDYDAFNMSREIIKKEGLLCGG 278
+ G D +EG+ DFVPD+ + +D+V + + +A +++ GLL G
Sbjct: 212 ALAGGRGED--HIEGLVSDFVPDIYSRYSRYVDRVVEVSSSEAIIGIAALLRATGLLAGP 269
Query: 279 SSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNY 313
S+GAA ++A R + G +V++ D + Y
Sbjct: 270 STGAAFVAATRLVECGALDRGSTIVIVAADHLSRY 304
>UniRef50_P53206 Cluster: Putative cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O-acetylserine
(Thiol)-lyase); n=12; Saccharomycetales|Rep: Putative
cysteine synthase (EC 2.5.1.47) (O-acetylserine
sulfhydrylase) (O-acetylserine (Thiol)-lyase) -
Saccharomyces cerevisiae (Baker's yeast)
Length = 393
Score = 115 bits (276), Expect = 3e-24
Identities = 96/336 (28%), Positives = 158/336 (47%), Gaps = 36/336 (10%)
Query: 18 ETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR 77
E IG+TPLV++ + K G+ ++AK E NP GS KDR++ ++ A++ G G
Sbjct: 51 ELIGNTPLVKIRSLTKATGVN--IYAKLELCNPAGSAKDRVALNIIKTAEELGELVRGEP 108
Query: 78 --FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWES 135
E TSG+TGI +A+ G+ I PD S EK++ + LGA V + + +
Sbjct: 109 GWVFEGTSGSTGISIAVVCNALGYRAHISLPDDTSLEKLALLESLGATVNKVKPASIVDP 168
Query: 136 SEHFLSVAK--RRLLEDPN---AISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXX 189
+++ + K L + N A+ DQ++N+ N + HY+ T EI ++D
Sbjct: 169 NQYVNAAKKACNELKKSGNGIRAVFADQFENEANWKVHYQTTGPEIAHQTKGNIDAFIAG 228
Query: 190 XXXXXXXXXXAQKVKEKCP-KCIIVTVDPQGSLIFG-------------EGPADLY---- 231
A+ +KE+ C +V DPQGS + EG +
Sbjct: 229 CGTGGTITGVAKFLKERAKIPCHVVLADPQGSGFYNRVNYGVMYDYVEKEGTRRRHQVDT 288
Query: 232 FVEGIGGDFVPD--VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIR 289
VEGIG + + + + ID+ + ND A M++ + +GL G S+ ++AI+
Sbjct: 289 IVEGIGLNRITHNFHMGEKFIDESIRVNDNQAIRMAKYLSVNDGLFVGSSTAINAVAAIQ 348
Query: 290 AAKKLNFGAGKRVVVILPDGIRNYMTKFVCDQWMEA 325
AK L G+ +V+I D +++KF W EA
Sbjct: 349 VAKTLPHGS--NIVIIACDSGSRHLSKF----WKEA 378
>UniRef50_A0ITV5 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Serratia proteamaculans 568|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Serratia proteamaculans 568
Length = 330
Score = 114 bits (275), Expect = 4e-24
Identities = 84/314 (26%), Positives = 146/314 (46%), Gaps = 10/314 (3%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS-GI 71
++++ + + D+ + N+ GL ++F K E +N GGSIK + + ++ +A KS G+
Sbjct: 3 FDSVDKLVNDSIFFKFNKF---CGL-ADLFVKVEGMNAGGSIKMKTAIALIRDAIKSKGL 58
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
K+ RFIE +SGN G+ +++ A G T V S + + + LG +VV
Sbjct: 59 YKT-KRFIESSSGNLGLSLSIIAAAKGLHFTCVVDKNTSSQNVKMMRALGTQVVIIEHKD 117
Query: 132 PWES-SEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXX 190
+ L+ + + DP I +QY+N NP H E TA+ IL VD +
Sbjct: 118 EQGGYLGNRLAYIRSAIERDPELIWLNQYQNMANPAVHAEMTAKSILTEFSKVDYLFIGA 177
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVI 250
A+ + PK ++ VD GS+ FG P + G+G P DKS +
Sbjct: 178 GTTGTLMGCARFFRRYSPKTKLIAVDSIGSITFGT-PGQTRHLPGLGSSVQPHFFDKSQV 236
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGI 310
D + + + + R+ ++ G L GG+S +++A++ + + VV I PD
Sbjct: 237 DLLIQIPEAETVATCRDAARRFGYL-GGASTGTVLAAVK-RMRADIAQEAIVVAISPDMG 294
Query: 311 RNYMTKFVCDQWME 324
Y+ D+W +
Sbjct: 295 SGYVDTVYNDEWCD 308
>UniRef50_A3SLF6 Cluster: Cysteine synthase; n=2; Bacteria|Rep:
Cysteine synthase - Roseovarius nubinhibens ISM
Length = 321
Score = 114 bits (274), Expect = 5e-24
Identities = 94/314 (29%), Positives = 145/314 (46%), Gaps = 13/314 (4%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I ++++ IGDTPLV L+R+ + GL + AK +++ PG S KDR + T++ A+ SG
Sbjct: 2 ILPSVIDAIGDTPLVSLDRVVTELGLSGRILAKLDYLLPGFSKKDRAARTIIEAARASGE 61
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP--- 128
+ G IE TSGN G G+A+ V G V + NS E+ + LGAEVV P
Sbjct: 62 LRDGQPVIELTSGNMGTGLAIVCGVLGHPFIAVMSEGNSPERARMMRALGAEVVLVPQAK 121
Query: 129 AMAPWESSEHFLS---VAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VD 184
P E S L+ A +R+ + A DQ+ NP H+ TA EI A + V
Sbjct: 122 GSRPGEVSGADLARVEEAAQRITRERAAFRADQFARPGNPAAHFHGTAPEIWAQSGETVS 181
Query: 185 MIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDV 244
+ A + + +C V+P G+ G G GG + D
Sbjct: 182 VFADFAGSGGTLAGCAAYLAPRGVRC--YAVEPTGAEAIGGGDRSTPAHPIQGGGYDMDA 239
Query: 245 LD--KSVIDK-VEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
L KS + +A + +R + ++EG+ G SSGA + +A++ + G G
Sbjct: 240 LAHLKSTDSAGTVTVSGNEARDHARLLARREGIFGGFSSGANLAAAVQLLRGPERG-GTI 298
Query: 302 VVVILPDGIRNYMT 315
+VI G++ T
Sbjct: 299 AIVICDSGLKYLST 312
>UniRef50_A1ZVV4 Cluster: Cysteine synthase (O-acetylserine
sulfhydrylase) (O-acetylserine (Thiol)-lyase); n=1;
Microscilla marina ATCC 23134|Rep: Cysteine synthase
(O-acetylserine sulfhydrylase) (O-acetylserine
(Thiol)-lyase) - Microscilla marina ATCC 23134
Length = 311
Score = 111 bits (268), Expect = 3e-23
Identities = 83/308 (26%), Positives = 142/308 (46%), Gaps = 16/308 (5%)
Query: 8 TRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQ 67
T + + + + IG+TPLV L+R+ K+ + ++ AK E+ GGS+K R ++ ++ +A
Sbjct: 9 TLEKRLHQVSQLIGNTPLVALDRVYKNP--KVQILAKLEWQQLGGSVKARPAFNIIKQAI 66
Query: 68 KSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT 127
G ++ +SGNTGI A G + P+ S E+ + G ++V T
Sbjct: 67 LHGQLDQNRVLLDASSGNTGIAYGAVGAALGIQVALCLPENASKERKMILRAHGVDIVYT 126
Query: 128 PAMAPWESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVP-DVDM 185
PA E ++ AK ++P+ DQY N N + HY +TA EI+ ++
Sbjct: 127 PAT---ELTDGAQIKAKELHAQNPDLYFYADQYANPHNWQAHYAHTAPEIIEQTQGEITH 183
Query: 186 IXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVL 245
++++KE P IV++ P + EG + VP
Sbjct: 184 FVAGLGTSGTFMGTSRRLKEYNPGIEIVSLQPDSPMHGLEGWKHMETA------IVPQFY 237
Query: 246 DKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVI 305
D S+ DK + + +DA+ + +E+ +KEGLL S+ A + AI A + G +V +
Sbjct: 238 DDSLADKNLEVSTFDAYELIKEVAQKEGLLISPSAAANLAGAIALADTIEEGT---IVTM 294
Query: 306 LPDGIRNY 313
PD Y
Sbjct: 295 FPDSADKY 302
>UniRef50_A2FS17 Cluster: Cysteine synthase; n=1; Trichomonas
vaginalis G3|Rep: Cysteine synthase - Trichomonas
vaginalis G3
Length = 235
Score = 111 bits (268), Expect = 3e-23
Identities = 64/166 (38%), Positives = 97/166 (58%), Gaps = 6/166 (3%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
IY+NILETIG+TPLVR+N + + + +M+AK E NP GS+KDRI+ M+ +A+ G
Sbjct: 2 IYDNILETIGNTPLVRINHLNPNP--KVQMYAKLEGFNPTGSVKDRIALKMIEQAKAEGK 59
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
+ G+ IE TSGNTGIG+A+ V G+ IV + S E+ I GA+++ T
Sbjct: 60 LQPGSTIIEATSGNTGIGLAMIGRVKGYNVIIVMSEGVSIERRKMIKAFGADIILTDKKL 119
Query: 132 PWESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEI 176
++ + + E+P + +Q+ N+ N HY+ TAEEI
Sbjct: 120 ---GTDGAIRKVAELVKENPGKYFNPNQFSNEYNKIAHYKTTAEEI 162
>UniRef50_A6TNQ8 Cluster: Pyridoxal-5'-phosphate-dependent protein,
beta subunit; n=1; Alkaliphilus metalliredigens
QYMF|Rep: Pyridoxal-5'-phosphate-dependent protein, beta
subunit - Alkaliphilus metalliredigens QYMF
Length = 442
Score = 111 bits (266), Expect = 5e-23
Identities = 106/406 (26%), Positives = 186/406 (45%), Gaps = 39/406 (9%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLE-CEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
+YNNI+E IG+TP++R+ P+ + L+ +++AK EF NP GS+KDR++Y M+ + K+
Sbjct: 2 LYNNIIELIGNTPILRI--APEVHKLKNIDIYAKLEFYNPFGSVKDRVAYGMIKDDIKN- 58
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
I ++ IE +SGNT + + A+ G VT E S + +LGAE+ + P +
Sbjct: 59 IKENNQTIIESSSGNTAKALQVLAAINGIEFKTVTNRIKIPEVKSILQMLGAEIEELPGL 118
Query: 131 A----PWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMI 186
+ P + ++ + + K E QY N N THY+ T +EI V VD
Sbjct: 119 SECPDPTDPNDPVIYIEKIMSQEANQYFHTAQYVNMKNRDTHYDTTGKEIYKDVGSVDYF 178
Query: 187 XXXXXXXXXXXXXAQKVKEKCPKCIIV-TVDPQGSLIFGEGPADLYFVEGIGGDFVPDVL 245
+ + EK V V +G I G D + GI
Sbjct: 179 FGTLGTTGSSRGIIEYLYEKNENMKKVGIVADKGDTIPGIRNIDEMYEVGI--------Y 230
Query: 246 DKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVI 305
+K + D + + +A + ++IK+ G+L G +SG A ++ ++++ G ++ +
Sbjct: 231 EKKLYDHIITVDSIEAIDGMLKLIKQCGVLGGPTSGGAFWGTLKYLQEIDEGLSEKKKAV 290
Query: 306 LPDGIRNYMTKFVCD--QWMEAHLFKEPPEREFLFFKGVLTKDSLRSEATNP-KKAGRID 362
VCD +W +++ K P+ F + K+++R+ + A I
Sbjct: 291 F----------VVCDRVEWYVSYIQKRRPD----LFDATIKKETIRNLSQEELSNATTIK 336
Query: 363 FNEPVNRHLIKTYYKIVENRGNPTVGLASRILDIAPFVIIVEAYYE 408
E + + K I++ RG GLA + I + IV+ Y+E
Sbjct: 337 IQEAL-EWVEKNNSLIIDLRG----GLAFKTSHIPNSINIVDDYFE 377
>UniRef50_A3Q5A0 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=23; Actinomycetales|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Mycobacterium sp. (strain JLS)
Length = 393
Score = 108 bits (259), Expect = 3e-22
Identities = 100/338 (29%), Positives = 146/338 (43%), Gaps = 14/338 (4%)
Query: 2 SNSRSFTRNRIYNNILET-IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISY 60
S++RS R N T +G TP++R++ E +AK E NPGG +KDR +
Sbjct: 34 SHTRSAQPQRGRNERPATMVGQTPVLRISA--PFTSEERGFWAKLEGFNPGG-MKDRPAL 90
Query: 61 TMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLL 120
MV A+ G G R +E TSG G+G+ALA V G T+VT + ++
Sbjct: 91 HMVERARSRGALAPGARIVESTSGTLGLGLALAGTVYGHPVTLVTDPGMEPIIQNMLAAF 150
Query: 121 GA--EVVQTP-AMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL 177
GA E+V P W+ + ++ L DP A DQY N N Y A E+
Sbjct: 151 GADIELVTEPHPQGGWQQARR--DRVQKILATDPRAWHPDQYSNPDNVEA-YRGLALELN 207
Query: 178 ALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIG 237
+ VD++ A+ ++E P+ ++ VD GS IFG+ PA + G+G
Sbjct: 208 EQLGAVDVLVCSVGTGGHSAGVARVLREFNPQLRLIGVDTVGSTIFGQ-PAASRLMRGLG 266
Query: 238 GDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFG 297
P +D ++V ++ R + G S GA + A A+ N
Sbjct: 267 SSIYPGNVDYQAFNEVHWVAPAESVWACRTLAATHYASGGWSVGAVALVAGWVAR--NSP 324
Query: 298 AGKRVVVILPDGIRNYMTKFVCDQWMEAH-LFKEPPER 334
AG V I PDG + Y D + AH L P R
Sbjct: 325 AGATVAAIFPDGPQRYFDTIYNDDYCRAHGLLDAAPPR 362
>UniRef50_Q08Q19 Cluster: Pyridoxal-phosphate dependent enzyme; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: Pyridoxal-phosphate
dependent enzyme - Stigmatella aurantiaca DW4/3-1
Length = 331
Score = 107 bits (257), Expect = 6e-22
Identities = 78/277 (28%), Positives = 125/277 (45%), Gaps = 5/277 (1%)
Query: 52 GSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSD 111
G +KDR++ + +A+ G K G E +SG G+A AV G+ IVT +
Sbjct: 3 GQMKDRVALKAIEDAEARGQLKPGGVIAESSSGTMAEGLARVGAVKGYKVIIVTDPRIDI 62
Query: 112 EKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLL-EDPNAISCDQYKNDVNPRTHYE 170
++ + GA+V P +H V R +L E+P A QY + NP + E
Sbjct: 63 GLLNKLRAFGAQVDVVETYHPTGGWQHSRLVRLREVLHENPGAFWPRQYDSPSNPGAYTE 122
Query: 171 YTAEEIL-ALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPAD 229
E++ AL P + + A+++K P IV VD GS+IF + P
Sbjct: 123 TMTHELVNALGPRIAALVGTVGSGGSLTGTAERLKALAPGVRIVAVDAVGSVIFHQ-PNG 181
Query: 230 LYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIR 289
G G + ++ VID+ +D + FN E+ ++E + GGSSGAA + A
Sbjct: 182 PRLQSGHGNSIIAGNINYRVIDEAHWLSDGEVFNACHELARRESIFGGGSSGAAYVVASW 241
Query: 290 AAKKLNFGAGKRVVVILPDGIRNYMTKFVCDQWMEAH 326
A++ FG + VV ++PD Y +++ H
Sbjct: 242 LAEQ--FGPDQHVVALMPDRGDRYCETIYSREYLAKH 276
>UniRef50_A6FEJ8 Cluster: Cysteine synthase, O-acetylserine (Thiol)
lyase B; n=1; Moritella sp. PE36|Rep: Cysteine synthase,
O-acetylserine (Thiol) lyase B - Moritella sp. PE36
Length = 297
Score = 106 bits (255), Expect = 1e-21
Identities = 76/283 (26%), Positives = 133/283 (46%), Gaps = 10/283 (3%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSG 75
+L+ IG+TPL+ L+ + +FAK E++NPGGS+KDR ++ A + G+ + G
Sbjct: 3 LLDLIGNTPLINLSFLSPQPE-RVSLFAKAEWMNPGGSLKDRSVKLILTRAIEDGLLQPG 61
Query: 76 TRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWES 135
++ +SGN GI ++ A G+ IV PD S+E+ + GA++++T A+ ++
Sbjct: 62 KIILDSSSGNAGISYSMIGAALGYAVNIVIPDNASNERKMRLRAHGAQLIETDALEGYDQ 121
Query: 136 SEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXXXXX 194
+ V + DQY N N HY T E++ V +
Sbjct: 122 A--IRHVHELYANSPDKYFFADQYSNQANVLAHYHGTGAELIEQVSGPITHFVCGVGTGG 179
Query: 195 XXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVE 254
A+++K K P +IV + P+ EG L G D +P + D S++D+
Sbjct: 180 SLTGIARRLKAKYPAVVIVGIRPERWPGI-EGLKPL----GEKEDILPKIFDGSLVDRWL 234
Query: 255 KPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFG 297
+ +A +M + ++ G G SSGA + + +L+ G
Sbjct: 235 DVSANEAKSMCLTMARR-GYFVGQSSGAYLAGCCKLMAELSEG 276
>UniRef50_Q5IWX8 Cluster: Plastid cysteine synthase; n=1; Prototheca
wickerhamii|Rep: Plastid cysteine synthase - Prototheca
wickerhamii
Length = 242
Score = 106 bits (255), Expect = 1e-21
Identities = 59/169 (34%), Positives = 89/169 (52%), Gaps = 4/169 (2%)
Query: 9 RNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQK 68
+N + +NI + IG+TPLVRLN + + G + + K E + P S+KDRI M+ +A++
Sbjct: 63 KNIVSSNITQVIGNTPLVRLNHLAETEGAKATILLKMESLEPNSSVKDRIGLAMIEDAEQ 122
Query: 69 SG-IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT 127
SG I T +EPTSGNTGI +A A G+ + P S E+ + GA++V T
Sbjct: 123 SGKITPGKTTLVEPTSGNTGIALAFVAAARGYKLVLTMPATMSLERRIVLRAFGAQLVLT 182
Query: 128 PAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI 176
P + + L A+ P++ Q++N NP HY T EI
Sbjct: 183 D---PAKGMKGALLKAEEIAAATPDSYILQQFENPANPAIHYTTTGPEI 228
>UniRef50_Q2RYV2 Cluster: Cysteine synthase B; n=1; Salinibacter
ruber DSM 13855|Rep: Cysteine synthase B - Salinibacter
ruber (strain DSM 13855)
Length = 466
Score = 106 bits (254), Expect = 1e-21
Identities = 90/280 (32%), Positives = 132/280 (47%), Gaps = 22/280 (7%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSG 75
IL IG TP+ +P + + K E NP S+KDRI+ ++ EA ++G
Sbjct: 165 ILGQIGGTPM-----LPYPGAEDGRLLCKMESANPTRSMKDRIAMGILTEALQNG---EY 216
Query: 76 TRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWES 135
R +E +SGNT VAL G CT+ P+ S K+ + GAEV P + +
Sbjct: 217 DRVVEASSGNTAGAVALVANRLGVPCTLTCPEGTSPHKIGYMKAFGAEVRTCPDVDS-DH 275
Query: 136 SEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALV-PDVDMIXXXXXXXX 194
+H+ +VA +R+ ED A DQY N NP HY++T EI A D+ +
Sbjct: 276 PDHYRAVA-QRIAEDTGAFLVDQYHNQSNPGVHYQWTGPEIWAQAGADMTHLVSAMGTGG 334
Query: 195 XXXXXAQKVKEKCPKC----IIVTVDPQGSLI---FGEGPADLY--FVEGIG-GDFVPDV 244
A+ VKE+ +V VD + S I F A Y VEG+G G +P +
Sbjct: 335 LVSGTARHVKEQAADAGRDVTVVGVDAEHSNISTSFYGADAVPYDTCVEGLGKGGELPTM 394
Query: 245 LDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAM 284
V D++ D +AF +RE + G+ G S+GAA+
Sbjct: 395 WFDHV-DEMRDVADEEAFRQAREAAQTHGMPVGPSAGAAL 433
>UniRef50_Q1AYU1 Cluster: Cysteine synthase; n=4; Bacteria|Rep:
Cysteine synthase - Rubrobacter xylanophilus (strain DSM
9941 / NBRC 16129)
Length = 327
Score = 105 bits (253), Expect = 2e-21
Identities = 74/284 (26%), Positives = 135/284 (47%), Gaps = 23/284 (8%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
++LE IGDTPL+ + E ++AK E++NP GSIK RI+ +V +A++ G+
Sbjct: 20 SVLEAIGDTPLIEV---------EEGIYAKLEYLNPSGSIKARIARYIVEKAEREGLLLP 70
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
G +E TSGNTG ++ A+ G+ ++ P+ S E+++ GA + E
Sbjct: 71 GHTIVEATSGNTGNAFSMVAAIKGYRMVVLMPEGLSTERVAISRAFGAHIEHVGEFYVTE 130
Query: 135 SSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-----VDMIXXX 189
+ + + K+ P Q+ ++ N + E+ +EIL + + D +
Sbjct: 131 ALKRARELGKKEGYFCP-----AQFDSEWNVEENREWLGKEILGQLEEGGVGAPDALVMG 185
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
Q +EK + ++ V+P+ S G + ++ +EGI FVP + ++
Sbjct: 186 VGTGGTLIGVGQAFREKNAEAKLIAVEPEESCTLLCGESGVHKIEGISDGFVPGIYERHA 245
Query: 250 ----IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIR 289
+D+V +A R + ++ GL G SSGA +++A R
Sbjct: 246 ERLGVDEVYAVGSEEALGAMRWLARRRGLFVGPSSGANLVAARR 289
>UniRef50_A0E1N6 Cluster: Cysteine synthase; n=2;
Oligohymenophorea|Rep: Cysteine synthase - Paramecium
tetraurelia
Length = 351
Score = 105 bits (251), Expect = 3e-21
Identities = 84/330 (25%), Positives = 150/330 (45%), Gaps = 26/330 (7%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG-IAKS 74
+ + IG+TPL+ L + + G E ++AKCEF+NPG S+KDR + ++ + G +
Sbjct: 25 LADIIGNTPLIYLKSLSEQTGRE--IYAKCEFMNPGSSMKDRTALALIQYGIQHGHLGVK 82
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
E TSG+TG+ + L G C + + + EK + + GA + + P ++ +
Sbjct: 83 NNTIYEGTSGSTGVSLTLIGNSLGCKCKLYLQNDLAQEKYNILQTCGAIIEKVPPVSIVD 142
Query: 135 SSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXX 193
SEHF A+++ + DQ+ N N + H++ T +EI +D
Sbjct: 143 -SEHFCKKAEKQAYIE-GGYYADQFHNLANQQAHFQ-TGKEIYKQTNGLIDCFVMSSGTG 199
Query: 194 XXXXXXAQKVKEKCPKCIIVTVDPQGSLI---FGEGPADLY--------------FVEGI 236
+Q +K K ++ DP GS + G Y +EG
Sbjct: 200 GSIAGISQYLKGKNKNIKVILADPPGSSLKTHVNSGVCYTYQEAEGHRLKNPFDTVIEGC 259
Query: 237 GGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNF 296
G + + ++ ID D ++ M+ +I+KEGL G SS ++ ++A +K +
Sbjct: 260 GLNRLTKNYLQAKIDYGFTIQDKESIQMAEFLIEKEGLFVGASSAMNCVAVLKAVEK--Y 317
Query: 297 GAGKRVVVILPDGIRNYMTKFVCDQWMEAH 326
K V IL D + Y++KF ++++ H
Sbjct: 318 PECKVFVTILCDSGQRYLSKFYNKEYLQQH 347
>UniRef50_Q8F4E4 Cluster: Cysteine synthase B; n=4; Leptospira|Rep:
Cysteine synthase B - Leptospira interrogans
Length = 333
Score = 104 bits (250), Expect = 4e-21
Identities = 79/304 (25%), Positives = 133/304 (43%), Gaps = 16/304 (5%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
+ IL+ IG+TPL+RLN+I E + K EF NP GS+KDR + +M+L +++ G
Sbjct: 37 VKETILQMIGNTPLIRLNQIGSHIP-NVEFYLKAEFCNPTGSVKDRTALSMLLSSERRGE 95
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP-AM 130
K + I+P T + +A + + + K+ + GA V P A
Sbjct: 96 LKPAGQVIQPGYNTTAMSLAWICTIRQYKFRCLVAGDTDPLKIKDLQTFGAHVEIVPGAK 155
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA-LVPDVDMIXXX 189
W+ S L AK ++ N I ++YK+ N HY +T EI L +VD
Sbjct: 156 GNWDDS--LLKRAKEIKEKEKNTIILNEYKDMANTNAHYLFTGPEIWRDLGGNVDAFVAG 213
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
+ +K K ++ Q S + V+ ++P+ D +
Sbjct: 214 GGSGGTLSGVGRFLKSKKSSVRVIMGVSQKSRFIRK------MVQNESSIYLPESFDPKI 267
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGK-----RVVV 304
+D+ + A ++ +KEG+ G ++G + SAIR A+ L+ R+VV
Sbjct: 268 VDEYVGVDREQALLYQSDLYQKEGIFAGQTTGTTLASAIRFAEGLSIKEDSKSQVYRIVV 327
Query: 305 ILPD 308
+ PD
Sbjct: 328 LSPD 331
>UniRef50_Q6A875 Cluster: Cystathionine beta-synthase; n=1;
Propionibacterium acnes|Rep: Cystathionine beta-synthase
- Propionibacterium acnes
Length = 333
Score = 104 bits (250), Expect = 4e-21
Identities = 88/317 (27%), Positives = 148/317 (46%), Gaps = 16/317 (5%)
Query: 12 IYNNILETIGDTPLVRL-NRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
I +I E ++ VRL N PK +++AK E +N GS+K + + +V +K
Sbjct: 2 IAGSIEELDENSQFVRLKNSFPKH-----DVYAKLEGLNTAGSVKLKTAIALVDSLEKLR 56
Query: 71 IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
+ G +E +SG+ GI ++ A G+ TIVT + +S + LGAEV ++
Sbjct: 57 GLQPGGWVVESSSGSLGIALSGVCARRGYKLTIVTDVNANSRSISHMRALGAEVEVVQSL 116
Query: 131 APWESSEHFLS--VAK-RRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVPDVDMI 186
+++ FL +A+ R L+E P + +QY+N NP H + T I+ + D D +
Sbjct: 117 ---DAAGGFLGTRLARVRELVEMPGGPLWTNQYENVANPEVHSKKTYRAIVEELGDPDYL 173
Query: 187 XXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLD 246
++ V ++ + +D GS+ FG P+ Y + G+G P + D
Sbjct: 174 FVGAGTTGTLMGVSRAVMKRGSCTKVCAIDSTGSVTFGGAPSRRY-IPGLGASVKPPIFD 232
Query: 247 KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVIL 306
+ K ++ D R I + EG L GGS+G +++A A + G RVV+I
Sbjct: 233 EKFPLKRYYIDEIDTVRQCRRIAQVEGFLPGGSTG-TVLAAFDALRD-KIPEGSRVVIIA 290
Query: 307 PDGIRNYMTKFVCDQWM 323
PD Y+ D W+
Sbjct: 291 PDLGERYLDGVYNDDWV 307
>UniRef50_A2FS16 Cluster: Cysteine synthase; n=1; Trichomonas
vaginalis G3|Rep: Cysteine synthase - Trichomonas
vaginalis G3
Length = 193
Score = 103 bits (247), Expect = 9e-21
Identities = 59/160 (36%), Positives = 92/160 (57%), Gaps = 6/160 (3%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
IY+NILETIG+TPLVR+N + + + +M+AK E NP GS+KDRI+ M+ +A+ G
Sbjct: 2 IYDNILETIGNTPLVRINHLNPNP--KVQMYAKLEGFNPTGSVKDRIALKMIEQAKAEGK 59
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
+ G+ IE TSGNTGIG+A+ V G+ IV + S E+ I GA+++ T
Sbjct: 60 LQPGSTIIEATSGNTGIGLAMIGRVKGYNVIIVMSEGVSIERRKMIKAFGADIILTDKKL 119
Query: 132 PWESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYE 170
++ + + E+P + +Q+ N+ N HY+
Sbjct: 120 ---GTDGAIRKVAELVKENPGKYFNPNQFSNEYNKIAHYK 156
>UniRef50_Q93H29 Cluster: CysK-like protein; n=3;
Actinomycetales|Rep: CysK-like protein - Streptomyces
avermitilis
Length = 360
Score = 102 bits (245), Expect = 2e-20
Identities = 74/251 (29%), Positives = 117/251 (46%), Gaps = 9/251 (3%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
+F KCE N GSIK + + MV A++ G+ + +E +SGN G+ +++ A G+
Sbjct: 27 LFLKCEGFNFAGSIKLKAATEMVEAAERDGVLTPESILVESSSGNLGVALSMIAASKGYR 86
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLS--VAKRRLL--EDPNAISC 156
VT + + + LG+EV +A E++ FL +A R L D +
Sbjct: 87 FLCVTDSRGNLSTRMMMEALGSEV---HMIAGQEANGGFLGARIAYVRALCASDDRYVWL 143
Query: 157 DQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVD 216
QY N N + HY TA EI P +D++ A+ +E IV VD
Sbjct: 144 SQYTNPSNWKAHYRKTAPEIARQFPRLDVLFVGAGTTGTLMGCARYFREWHRPVRIVAVD 203
Query: 217 PQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLC 276
GS+ FG GP + G+G P +LD+S +D+V + + D + ++ G L
Sbjct: 204 SVGSVSFG-GPPGRRMIPGLGMSMRPPLLDESYVDEVIRVEEADTIRTCHRLARR-GFLF 261
Query: 277 GGSSGAAMISA 287
GGS+G + A
Sbjct: 262 GGSTGTVVSGA 272
>UniRef50_A7DSI8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Candidatus Nitrosopumilus maritimus
SCM1|Rep: Pyridoxal-5'-phosphate-dependent enzyme, beta
subunit - Candidatus Nitrosopumilus maritimus SCM1
Length = 330
Score = 102 bits (244), Expect = 2e-20
Identities = 82/274 (29%), Positives = 133/274 (48%), Gaps = 14/274 (5%)
Query: 15 NILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS 74
++L +G+TPLV+L+ + D + FAK E NP GS+KDR +Y M+ + ++ GI
Sbjct: 8 DVLNRVGNTPLVKLDSLSHD---NVDYFAKLEGHNPFGSVKDRAAYWMIKDGEEKGILTK 64
Query: 75 GTRFI-EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT-PAMAP 132
G I EPTSGNTGI + + G+ IV P+K S+E I LGA+V +T + P
Sbjct: 65 GKSIIIEPTSGNTGIALTGIANLLGYKVEIVIPEKASNETKDIIRNLGAKVFETSDDLCP 124
Query: 133 --WESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVP-DVDMIXX 188
++ +++A P+ S +QY N+ N + HY T EI V
Sbjct: 125 KVGAGTDQSIALATSIASSRPDTYYSPNQYANEANFKGHYIGTGPEIWRQTEGKVTHFFT 184
Query: 189 XXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKS 248
+KEK P I+ PQ + + +G + F E D + ++
Sbjct: 185 GVGTGGTITGIGAFLKEKNPDVKIIGCQPQQNHLI-QGWRN--FEESAKPDLF--LKREN 239
Query: 249 VIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGA 282
V+D ++ +AF++ +++ +K+ LL SS A
Sbjct: 240 VVDDWVSVDNDEAFSVVKDVFEKDQLLISPSSAA 273
>UniRef50_Q2QD00 Cluster: Zwa5A; n=2; Bacillus cereus group|Rep:
Zwa5A - Bacillus thuringiensis
Length = 325
Score = 99 bits (238), Expect = 1e-19
Identities = 81/310 (26%), Positives = 134/310 (43%), Gaps = 16/310 (5%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
IG+TP+++L + ++AK E+ N S+K R ++ ++ A G + I
Sbjct: 12 IGNTPMIKLEHE------KINLYAKLEYHNLMNSVKVRAAHHILKSAISRGEVTENSTII 65
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTP-DKNSDEKMSTISLLGAEVVQTPAMAPWESSEH 138
E +SGN VALAT G + D N ++ + L A Q + + +
Sbjct: 66 ESSSGN--FAVALATLCRYIGLKFIPVIDPNINDSYE--NFLRATSYQVAKVDERDETGG 121
Query: 139 FLSVAKRRLLE----DPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXX 194
+L ++ E PNA +QY N N HY+ EI +D
Sbjct: 122 YLLTRLNKVEELLNTIPNAYWTNQYNNADNFEAHYQGIGGEISNDFKQLDYAFIGVSTGG 181
Query: 195 XXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVE 254
+ ++KEK P I+ VD QGS+IFG+ P Y + GIG +P ++ K++ID V
Sbjct: 182 TIAGVSTRLKEKFPNIKIIAVDSQGSIIFGDKPRKRY-IPGIGASMIPGMVKKALIDDVM 240
Query: 255 KPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYM 314
+ E+ K + GGSSG + + + + + VV + PD + Y
Sbjct: 241 IVPEVHTVAGCYELFNKHAIFAGGSSGTSYYAIQKYFENKDVQNTPNVVFLCPDNGQAYT 300
Query: 315 TKFVCDQWME 324
+ +W+E
Sbjct: 301 STIYNVEWVE 310
>UniRef50_Q0C5S8 Cluster: Cysteine synthase/cystathionine
beta-synthase family protein; n=8; Bacteria|Rep:
Cysteine synthase/cystathionine beta-synthase family
protein - Hyphomonas neptunium (strain ATCC 15444)
Length = 357
Score = 99.1 bits (236), Expect = 2e-19
Identities = 91/334 (27%), Positives = 147/334 (44%), Gaps = 22/334 (6%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
IG TP++ + + G E + AK E N GSIKDR++ +++ A +SG + G
Sbjct: 34 IGRTPMLSIRL--RFRGRERVIHAKAEHYNLTGSIKDRMALSILACAYRSGALQPGDTIA 91
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHF 139
E TSGN GI + G I PD S E+ + + LGA + + E+
Sbjct: 92 EATSGNAGIALTALGRALGHPVEIFMPDWMSGERKNLLRSLGANL----NLLSREAGGFL 147
Query: 140 LSVAKRRLLEDPNA---ISCDQYKNDVNPRTHYEYTAEEIL----ALVPDVDMIXXXXXX 192
++A L + C Q+ N N H + TA E++ L D
Sbjct: 148 GAIAATETLAASRKDVFLPC-QFSNGDNSAAHAQTTARELINQLATLDARPDAFVAGVGT 206
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEG-PADLYFVEGIGGDFVPDVLDKSVID 251
+ K P + ++PQ S G + ++GI DF+P ++ +D
Sbjct: 207 GGTVMGVGRAFKSAFPDVKVHPLEPQESPTLSTGYKVGQHRIQGISDDFIPALVKLEQVD 266
Query: 252 KVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
+V +D DA M++ + ++ GL G SSGA +I A+ AA++L G V + D +
Sbjct: 267 EVIAVSDGDAIRMAQRLARELGLGVGISSGANLIGALIAAERL--GDTACVATVFCDDNK 324
Query: 312 NYMT-KFVCDQ-WMEAHLFKEPPEREFLFFKGVL 343
Y++ C++ E HL PE E L F+ +
Sbjct: 325 KYLSGALACEEPHKEGHL---TPEIELLDFEATI 355
>UniRef50_Q1IBI7 Cluster: Putative Cysteine synthase; n=1;
Pseudomonas entomophila L48|Rep: Putative Cysteine
synthase - Pseudomonas entomophila (strain L48)
Length = 326
Score = 97.9 bits (233), Expect = 5e-19
Identities = 74/289 (25%), Positives = 127/289 (43%), Gaps = 9/289 (3%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
+F K E + GSIK + + MV + G G +E +SGN G+ +A+ A G+
Sbjct: 27 VFVKLEGFSLSGSIKVKPALRMVERLELEGRLGPGKALVESSSGNLGLALAMVCASKGYP 86
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVV---QTPAMAPWESSEHFLSVAKRRLLEDPNAISCD 157
T ++ S + I GA +V Q + S +++ + L EDP+ + +
Sbjct: 87 FTCISDPNISPQTAKLIRAYGARLVIVDQRDRNGGYLGSR--IALIEHLLAEDPHLVWTN 144
Query: 158 QYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDP 217
QY N N H T IL P D++ ++ ++E P +V VD
Sbjct: 145 QYGNINNVEAHMLSTGPAILRQFPHPDLVFVGAGTTGTLAGVSRYLREHSPHTQVVAVDS 204
Query: 218 QGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCG 277
GS+ FG P+ + G+G P++ D++ + +A M +++ ++ G+L G
Sbjct: 205 VGSVTFGH-PSGPRHIPGLGTSQPPEIRRHCCHDQLLMVPEEEAVAMCQKLARR-GILLG 262
Query: 278 GSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKFVCDQWMEAH 326
GSSG + R A+ + VV I PD Y+ +W++ H
Sbjct: 263 GSSGTVLAGVRRHAR--HIAPNACVVAIAPDLGDRYVDTLYNPEWVQRH 309
>UniRef50_Q9HRP3 Cluster: Cysteine synthase; n=2;
Halobacteriaceae|Rep: Cysteine synthase - Halobacterium
salinarium (Halobacterium halobium)
Length = 274
Score = 95.9 bits (228), Expect = 2e-18
Identities = 74/266 (27%), Positives = 115/266 (43%), Gaps = 14/266 (5%)
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
M+ + SG G IEPT+GNTG+G A+A + G V P++ S EK + LG
Sbjct: 1 MIEQMLASGELPEGGTIIEPTAGNTGVGFAVAASQLGIDAVFVVPERFSLEKQQLMRALG 60
Query: 122 AEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL-ALV 180
A+VV TP + + A E +AI Q+ N +N HYE T EI AL
Sbjct: 61 ADVVNTPTD---DGMGGAIQRAHDLAAEREDAIVPQQFSNPLNAEAHYETTGPEIYHALD 117
Query: 181 PDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADL----YFVEGI 236
V ++ ++++ + V+P+GS+ AD+ Y EGI
Sbjct: 118 GAVGAFVAGCGTAGTLMGTSRFLRDQISALHVTAVEPEGSMYASAAGADVSEGEYKTEGI 177
Query: 237 G--GDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKL 294
G ++ D +D V + D D + + +E L S+ A ++AI A++
Sbjct: 178 GTHDPSTSELFDPEFVDDVTQIPDEDTHAEMQRLAAEEAQLVASSAAANSLAAIDVAERA 237
Query: 295 NFG----AGKRVVVILPDGIRNYMTK 316
G VV + PD Y++K
Sbjct: 238 AAGHIDLPHDCVVTVFPDSSERYLSK 263
>UniRef50_Q0DBH7 Cluster: Os06g0564400 protein; n=4; Oryza
sativa|Rep: Os06g0564400 protein - Oryza sativa subsp.
japonica (Rice)
Length = 399
Score = 94.7 bits (225), Expect = 4e-18
Identities = 64/213 (30%), Positives = 95/213 (44%), Gaps = 5/213 (2%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
I +N+ + IG TPL+ + I K G++ + K E P S+KDR + MV +A++ G+
Sbjct: 31 IASNVAQLIGWTPLIEMKNIAKKEGIQARLVGKMEAYQPLFSVKDRTALGMVEDAEEKGL 90
Query: 72 AKSG-TRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAM 130
G T IEPT GN G G+ L G+ V P S +K + LGAEV+ T
Sbjct: 91 ITPGVTTLIEPTGGNLGTGLVLVAIQRGYRFIAVMPAGYSLDKQMLLRFLGAEVILTD-- 148
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA-LVPDVDMIXXX 189
P + + + PN +Q N NP H+++T EI VD+
Sbjct: 149 -PAGGFKGMMDKVEELTKVMPNYHCFNQSINPANPDAHFKWTGPEIWKDTAGKVDIFVTA 207
Query: 190 XXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLI 222
+ +K K P IV V+P S +
Sbjct: 208 AGTGGTLSGVGRYLKMKNPSINIVCVEPSESAV 240
>UniRef50_Q95PN6 Cluster: Cystathionine beta-synthase; n=1;
Ostertagia ostertagi|Rep: Cystathionine beta-synthase -
Ostertagia ostertagi
Length = 186
Score = 93.1 bits (221), Expect = 1e-17
Identities = 43/90 (47%), Positives = 62/90 (68%), Gaps = 1/90 (1%)
Query: 9 RNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQK 68
R + YNNILE G+TPL +LN+IP DY L+C ++ K E++N GGS++DR + MV A++
Sbjct: 46 RAKWYNNILEANGNTPLSKLNKIPLDYSLKCNIYVKLEYLNAGGSMEDRAAIRMVEVAEQ 105
Query: 69 SGIAKSGTRFIEPTSGNTGIGVALATAVCG 98
+G+ K + P SGN +G+ALA AV G
Sbjct: 106 NGLTKD-RAVVAPASGNVAVGIALACAVKG 134
>UniRef50_Q50059 Cluster: CysS; n=1; Mycobacterium leprae|Rep: CysS
- Mycobacterium leprae
Length = 171
Score = 91.9 bits (218), Expect = 3e-17
Identities = 50/104 (48%), Positives = 65/104 (62%), Gaps = 4/104 (3%)
Query: 11 RIYNNILETIGDTPLVRLNRI-PKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
RI +I + IG TPLVRLN + P G+ + AK E+ N GGS KDRI+ M+ A+ S
Sbjct: 2 RIAQHISDLIGGTPLVRLNSVVPAGTGV---VAAKVEYFNSGGSSKDRIAAKMIDAAEAS 58
Query: 70 GIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEK 113
G K G +EPTSGNTG+G+AL G+ C V PDK S++K
Sbjct: 59 GQLKPGGTIVEPTSGNTGVGLALVAQHRGYKCVFVCPDKVSEDK 102
>UniRef50_Q0UV41 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 413
Score = 91.9 bits (218), Expect = 3e-17
Identities = 91/325 (28%), Positives = 136/325 (41%), Gaps = 49/325 (15%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
IGDTPL+++ + G CE+ AK E G +L + SG
Sbjct: 89 IGDTPLIKIKSLSNYTG--CEILAKAEAEEKG-----------LL------VPNSGDTIY 129
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHF 139
E T G+TGI +A G+ I P+ + EK + LGAE V+ AP F
Sbjct: 130 EGTVGSTGISLAAICRARGYKAHICMPNDMATEKSELLLKLGAE-VERVRPAPIVDQNQF 188
Query: 140 LSVAKRRLLEDP-------NAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXX 191
+++A+ R E + DQ++ + N R H+ T EI VD
Sbjct: 189 VNLARARAAEHTASADKPGRGLFADQFETEANWRAHFAGTGPEIYEQTGGAVDAFVSGAG 248
Query: 192 XXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYF-----------------VE 234
A +K K P IV DP GS ++ + F VE
Sbjct: 249 TGGTISGVALYLKSKLPNIKIVLADPPGSGLYNRVKYGVMFDRKEREGTRRRHQVDTIVE 308
Query: 235 GIGGDFVPDVLD--KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAK 292
GIG + V D + +ID + ND A +M+R +++ +G+ G SS ++A + AK
Sbjct: 309 GIGINRVTHNFDVGRELIDDAIRVNDEQAIDMARWLVEHDGIFVGSSSAVNCVAATQLAK 368
Query: 293 KLNFGAGKRVVVILPDGIRNYMTKF 317
L G G R+V IL D +++KF
Sbjct: 369 TL--GPGHRIVTILCDSGARHLSKF 391
>UniRef50_Q54312 Cluster: Cystathione synthase; n=1; Streptomyces
hygroscopicus|Rep: Cystathione synthase - Streptomyces
hygroscopicus
Length = 207
Score = 89.4 bits (212), Expect = 2e-16
Identities = 58/192 (30%), Positives = 92/192 (47%), Gaps = 3/192 (1%)
Query: 38 ECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVC 97
+C++ AK EF NP GS KDR + ++ +A G T +E +SGN + +A +
Sbjct: 12 QCDIVAKLEFCNPTGSSKDRSALWILEQAIGRGEIARSTTVVESSSGNFALALAFYCRML 71
Query: 98 GFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESS--EHFLSVAKRRLLEDPNAIS 155
G V D N +E L E V+ A+ S ++ LS + L+E +A
Sbjct: 72 GISFVPVI-DPNCNEATEAQLRLLCERVEKVAIRDGSGSYLKNRLSRVRELLVELDSAYW 130
Query: 156 CDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTV 215
+QY N HY +TA E++A +D + ++++KE P C++V V
Sbjct: 131 PNQYANPDARDAHYHFTAGELIAQAGPLDYLFVGVGTGGTIAGLSRRIKETYPDCVVVAV 190
Query: 216 DPQGSLIFGEGP 227
D +GS+IFG P
Sbjct: 191 DAEGSVIFGGPP 202
>UniRef50_A7D608 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: Pyridoxal-5'-phosphate-dependent enzyme, beta
subunit - Halorubrum lacusprofundi ATCC 49239
Length = 339
Score = 89.4 bits (212), Expect = 2e-16
Identities = 76/259 (29%), Positives = 120/259 (46%), Gaps = 19/259 (7%)
Query: 19 TIGDTPLVRLNRIPKDYGLECEMFAKCEFVN------PGGSIKDRISYTMVLEAQKSGIA 72
TI +TPLV+L+ D + +++AK E+ N GGSIK RI+ M+ A++ G
Sbjct: 10 TIFETPLVKLDL---DIESDADVYAKAEWFNLYDAPHGGGSIKSRIAKGMIDGAEERGDL 66
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
G IEPTSGNTG +A G+ IV PD + K+ + GAE+ A
Sbjct: 67 DPGVTVIEPTSGNTGSEIARLAGSRGYDVEIVMPDNAAGGKVDAVRDAGAEIHFVDANLG 126
Query: 133 WESSEHFLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEIL-ALVPDVDMIXXXX 190
+++ + + + EDP A +QY+N NP TH TA EI A +V
Sbjct: 127 YDA---VIERCEEIIAEDPEAYFRPNQYENPDNPGTHERTTAREIYGATDGEVTHFVAGV 183
Query: 191 XXXXXXXXXAQKVKEKCPKCI-IVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
+ + + + IV +P L +G L +++ G + PD D+S
Sbjct: 184 GTGGTITGTGRGLTDLSDGAVEIVGFEPDEQLHAIDG---LKYLKS-GDHYHPDTYDESA 239
Query: 250 IDKVEKPNDYDAFNMSREI 268
+D+ E DA++ +R +
Sbjct: 240 LDRTEYVTTSDAYDRARAL 258
>UniRef50_A6QZJ2 Cluster: Cysteine synthase; n=1; Ajellomyces
capsulatus NAm1|Rep: Cysteine synthase - Ajellomyces
capsulatus NAm1
Length = 409
Score = 88.2 bits (209), Expect = 4e-16
Identities = 82/296 (27%), Positives = 130/296 (43%), Gaps = 30/296 (10%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVN-PGGSIKDRISYTMVLEAQKSG 70
I + I IG+TPL R+ + + G CE+ AK EF+N GGS KDR++ ++ A++ G
Sbjct: 80 IVDGIEGCIGNTPLFRIKSLSEATG--CEILAKAEFLNGAGGSPKDRVALNVIQVAEEKG 137
Query: 71 IAK--SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTP--DKNSDEKMSTISLLGAEVVQ 126
+ SG E T G+TGI +A G+ I +S S+ + +
Sbjct: 138 LLHPYSGDAIYEGTVGSTGISLATLARARGYLAHIARALAKSHSSSPESSPARASSRTSH 197
Query: 127 TPAMAP--WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-V 183
P E+ + L V+ R + DQ++N N + H+ T EI A +
Sbjct: 198 NPPATHEITETPDEDLLVS-RAAGKQSRGFFADQFENPANWQAHFRTTGPEIFAQCESKL 256
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYF----------- 232
D+ A+ +K + P +V DPQGS +F + F
Sbjct: 257 DVFVAGAGTGGTISGVARFLKPRLPNMSVVLADPQGSGLFNRVRYGVMFDVKEREGTRRR 316
Query: 233 ------VEGIGGDFVPDVLD--KSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSS 280
VEGIG + V + + +ID V + ND A M+R +++K+G+ G SS
Sbjct: 317 RQVDTIVEGIGINRVTLNFEAGRELIDDVVRVNDAQAIAMARWLVEKDGIFIGSSS 372
>UniRef50_Q0AFB1 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Nitrosomonas eutropha C91|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Nitrosomonas eutropha (strain C71)
Length = 647
Score = 87.8 bits (208), Expect = 5e-16
Identities = 83/330 (25%), Positives = 146/330 (44%), Gaps = 19/330 (5%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
+ ++I + IG+TP+++LN K +++AK E +NP GSIKDR ++ M L +
Sbjct: 319 VVDSITDLIGNTPILKLNPA-KTSLTNIDLYAKLEHLNPFGSIKDRTAWAM-LRPHLGTL 376
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA-M 130
S + +E +SGN + ++ G +T E + + GA+V +
Sbjct: 377 QSSNKQLLELSSGNAARALQAVASIYGSALETITNRIRIQEMRRMLVVQGAKVSPMAGDV 436
Query: 131 APWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXX 190
P ++ L V R + + DQY+N N THY TA+EIL + VD
Sbjct: 437 DPTDAMAALLYVDARAYEQRDRYLYTDQYRNPNNDCTHYATTAQEILEDLGPVDYFFAPV 496
Query: 191 XXXXXXXXXAQKVKEKCPKC-IIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV 249
++++E K + V + S I G D F G ++
Sbjct: 497 GTAGSSIGIGRRLREANEKLKVSGIVSTKDSAIPGIRHMDEMFYVG--------PFEEQK 548
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR--VVVILP 307
D++ +A + +I+ G++ G SSGA ++A+R + ++ +R V+I+
Sbjct: 549 YDQLVGITASEALDGMLALIRDYGVMAGPSSGATYLAALRYLRAIDAKQTERKSAVIIVC 608
Query: 308 DGIRNYMTKFVCDQWMEAHLFK--EPPERE 335
D + Y++ + M LF+ E PE E
Sbjct: 609 DRVELYLSWI---EQMRPALFEDYETPEAE 635
>UniRef50_Q8TZW7 Cluster: Cysteine synthase; n=4; Archaea|Rep:
Cysteine synthase - Pyrococcus furiosus
Length = 284
Score = 86.2 bits (204), Expect = 2e-15
Identities = 79/276 (28%), Positives = 127/276 (46%), Gaps = 26/276 (9%)
Query: 42 FAKCEFVNP-GGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
FAK EF NP SIKDR Y M+++A +SG E TSGN GI +A +AV G
Sbjct: 3 FAKLEFFNPFSRSIKDRPVYNMIMKAIESGEIDGTDTLYEATSGNVGIALAALSAVLGLK 62
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE-HFLSVAKRRLLEDPNAISCDQY 159
P I + GAEV++T +E+ + F++ K +D A++ +Q+
Sbjct: 63 FRAYVPKPTPKITEILIKMFGAEVIRT----KFETIDPEFINFVKEEAKKD-KAVNLNQF 117
Query: 160 KNDVNPRTHYEYTA----EEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTV 215
+ND N HY TA E++ ++ ++I ++ KEK II V
Sbjct: 118 ENDANFEAHYYGTAKELDEQLKSIKKKPEVIIAGVGTSGHIAALSKYFKEKYGTKIIGVV 177
Query: 216 DPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLL 275
+G I G ++ I + P + +DKV + +A + + + +GL+
Sbjct: 178 PAEGEKIPG--------IKRI--ETKPKWFFQVKVDKVVEITTREAVEGALRVARTDGLI 227
Query: 276 CGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIR 311
G SSGA ++A +K+N G V++ DG +
Sbjct: 228 IGLSSGA----VVKAYEKIN-PKGTTVLIFPDDGFK 258
>UniRef50_A3AFH4 Cluster: Cysteine synthase; n=3; Oryza sativa|Rep:
Cysteine synthase - Oryza sativa subsp. japonica (Rice)
Length = 482
Score = 85.4 bits (202), Expect = 3e-15
Identities = 43/112 (38%), Positives = 66/112 (58%), Gaps = 2/112 (1%)
Query: 3 NSRSFTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTM 62
+SRS R ++E IG+TPL+R+N + G CE+ K EF+NPGGS+KDR++ +
Sbjct: 39 SSRSSGRRTRRKGLVEAIGNTPLIRINSLSDATG--CEILGKAEFLNPGGSVKDRVAVKI 96
Query: 63 VLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKM 114
+ EA +SG G E ++G+T I +A+ G C +V PD + EK+
Sbjct: 97 IEEALESGDLLCGGTVTEGSAGSTAISLAIVAPAYGCKCHVVIPDDAAIEKV 148
Score = 63.7 bits (148), Expect = 9e-09
Identities = 55/189 (29%), Positives = 81/189 (42%), Gaps = 22/189 (11%)
Query: 157 DQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTV 215
DQ++N N R HYE+T EI + ++ +KEK +
Sbjct: 284 DQFENMANYRAHYEWTGPEIWQQSKGTLHAFVAAAGTGGTIAGVSRYLKEKNTNIKCFLM 343
Query: 216 DPQGSLIFG-------------EG-----PADLYFVEGIGGDFVPDVLDKSVIDKVEKPN 257
DP GS +F EG P D EGIG + V + +D +
Sbjct: 344 DPPGSGLFNKVTRGVMYTKEEAEGKRLKNPFDT-ITEGIGINRVTKNFMMAELDGAYRGT 402
Query: 258 DYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKF 317
D +A MSR ++K +GL G SS + A+R A+ L G G +V IL D +++KF
Sbjct: 403 DREAVEMSRFLLKNDGLFVGSSSAMNCVGAVRVAQDL--GPGHTIVTILCDSGMRHLSKF 460
Query: 318 VCDQWMEAH 326
DQ++ H
Sbjct: 461 FNDQYLANH 469
>UniRef50_Q4PCE5 Cluster: Cysteine synthase; n=1; Ustilago
maydis|Rep: Cysteine synthase - Ustilago maydis (Smut
fungus)
Length = 537
Score = 85.4 bits (202), Expect = 3e-15
Identities = 46/138 (33%), Positives = 80/138 (57%), Gaps = 5/138 (3%)
Query: 11 RIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSG 70
++ + + IG+TPL+R+N + + G CE+ K EF+NP GS KDR++ ++ +A++ G
Sbjct: 106 QVVSGVEGLIGNTPLMRINSLSEATG--CEILGKAEFLNPAGSPKDRVALQILKDAEEEG 163
Query: 71 IA--KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
+ +G+ E T G+TGI +A G+ C+IV PD + EK+ + LGAE +++
Sbjct: 164 LLYPHTGSCIFEGTVGSTGISLATLARAKGYRCSIVIPDDVAREKVELLEKLGAE-IESV 222
Query: 129 AMAPWESSEHFLSVAKRR 146
HF++ A+ R
Sbjct: 223 RPRGIVDPRHFVNEARAR 240
Score = 44.0 bits (99), Expect = 0.008
Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 6/91 (6%)
Query: 233 VEGIGGDFVPDVLDKSV--IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRA 290
VEGIG + + L + ID E+ +D +A M R +I +GL G SS ++A+R
Sbjct: 420 VEGIGINRITRNLQMGLQCIDDAERVSDDEAARMGRHLILNDGLFLGSSSAVNCVAAVRT 479
Query: 291 AKKLNFGAGKR----VVVILPDGIRNYMTKF 317
A K+ G VV +L D +++KF
Sbjct: 480 ALKIKRQRGDDPPPVVVTVLCDSGSRHLSKF 510
>UniRef50_A6DD26 Cluster: Cysteine synthase; n=1; Caminibacter
mediatlanticus TB-2|Rep: Cysteine synthase -
Caminibacter mediatlanticus TB-2
Length = 272
Score = 85.0 bits (201), Expect = 3e-15
Identities = 81/280 (28%), Positives = 129/280 (46%), Gaps = 28/280 (10%)
Query: 44 KCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTI 103
K E+ NP GSIKDR + ++ K K +E TSGNTGI ++ TI
Sbjct: 15 KLEYKNPAGSIKDRPALFII----KDAFLKGYKEVVEVTSGNTGIALSFYAQKFNIKATI 70
Query: 104 VTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDV 163
P S E+ + GA ++ T + + L AK ++ NA +Q++N +
Sbjct: 71 FMPKTFSIERQKLLRAYGANLILTDG-----TIKDALQEAK-EYIKKHNAYYSNQFENLL 124
Query: 164 NPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGS-LI 222
N + E TA EI+ +D A+ +K K I+TV+ + + LI
Sbjct: 125 NSKAQ-EITALEIINQTQKIDYFVSGVGSGGSISGIAKILKPIGVK--IITVESKNAPLI 181
Query: 223 FGE-----GPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCG 277
+ + P + ++GIG F+P +LD ++ID V +D +A E +KK L G
Sbjct: 182 YNQLHNKNLPIHPHKIQGIGAGFIPKILDINLIDDVILIDDDEAI----EFMKKMPKL-G 236
Query: 278 GSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKF 317
+ G + + I A+KKL +V + PDGI Y++ F
Sbjct: 237 ITGGISTAANILASKKLQ----GNIVTLAPDGIEKYLSIF 272
>UniRef50_Q5KCX2 Cluster: Cysteine synthase; n=2; Filobasidiella
neoformans|Rep: Cysteine synthase - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 458
Score = 84.6 bits (200), Expect = 5e-15
Identities = 47/142 (33%), Positives = 80/142 (56%), Gaps = 5/142 (3%)
Query: 10 NRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
+ I + IG+TPL+R+N + G+E + K EF+NPGGS+KDR++ ++ +A+
Sbjct: 71 DEIVPGVTGLIGNTPLIRINSLSDALGVE--ILGKAEFLNPGGSVKDRVALQIIEDAEAQ 128
Query: 70 GI--AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT 127
G+ +G+ E T G+TGI +A G+ I+ PD + EK+ + LGA V+
Sbjct: 129 GLLYPNTGSVLFEGTVGSTGISLATVGKAKGYESCIIMPDDVAIEKVQILEKLGAR-VER 187
Query: 128 PAMAPWESSEHFLSVAKRRLLE 149
A + F+++A++R LE
Sbjct: 188 VRPASIVDQKQFVNLARKRALE 209
Score = 70.5 bits (165), Expect = 8e-11
Identities = 63/226 (27%), Positives = 97/226 (42%), Gaps = 24/226 (10%)
Query: 121 GAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALV 180
G E+ + A P E + H L + P DQ++ND N HY+ T EIL
Sbjct: 222 GEEIAVSTAAEPSEINHHHLFPSAFE--HKPRGFFADQFENDSNFMAHYKGTGPEILRQT 279
Query: 181 PD-VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYF------- 232
+D +K+ P IV DP+GS +F + ++ F
Sbjct: 280 SGHLDGFVSGAGTGGTIAGTGCFLKKALPDLKIVLSDPEGSGLFNKVRFNVMFDPKESEG 339
Query: 233 ----------VEGIGGDFVPD--VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSS 280
VEGIG + + L VID + +D +A MSR +++ +GL G SS
Sbjct: 340 KKRRHQVDTVVEGIGINRITYNFSLGLPVIDDAYRVSDEEAVAMSRYLVQHDGLFLGSSS 399
Query: 281 GAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKFVCDQWMEAH 326
+I+ IR AK ++ G R+ IL D + +KF D ++ A+
Sbjct: 400 ACNLIACIRLAKTMS--RGSRIATILCDSGSRHQSKFWSDDYLRAN 443
>UniRef50_Q0RLF9 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 432
Score = 84.2 bits (199), Expect = 6e-15
Identities = 38/94 (40%), Positives = 63/94 (67%), Gaps = 2/94 (2%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
++ ++L+ IG+TPL RL R+ + G+ ++AK EF+N GGS+KDR + +MVL+A++ G+
Sbjct: 3 VHESVLDAIGETPLFRLTRLGR--GIATPLYAKAEFLNIGGSVKDRAALSMVLQAERDGL 60
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVT 105
+ G +E TSGN GIG+A+ G+ + T
Sbjct: 61 LRPGGTIVEATSGNIGIGLAIIGRQRGYRVIVGT 94
>UniRef50_A3KIP2 Cluster: Putative pyridoxal-phosphate dependent
enzyme; n=1; Streptomyces ambofaciens ATCC 23877|Rep:
Putative pyridoxal-phosphate dependent enzyme -
Streptomyces ambofaciens ATCC 23877
Length = 445
Score = 84.2 bits (199), Expect = 6e-15
Identities = 84/317 (26%), Positives = 143/317 (45%), Gaps = 26/317 (8%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLE-CEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
Y++I E IG+TPLVR++ P +GL +++AK E +NP GS+KDR ++ M +
Sbjct: 3 YDSITEAIGNTPLVRID--PAVHGLRNIDLYAKLEMLNPFGSVKDRPAWHMARPHLEGAG 60
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP--- 128
A GT +E +SGNT +AL + G VT E + LLGAE+ + P
Sbjct: 61 AGEGT-VVELSSGNTAKALALLAGMHGLRFKSVTNRMRVPEIKELLLLLGAEIEELPGRS 119
Query: 129 -AMAPWESSEHFLSVAKRRLLEDPNA--ISCDQYKNDVNPRTHYEYTAEEILALVPD--V 183
+ P ++ + + L +P + + DQY N N H T EI+ +
Sbjct: 120 ECLDPTDTDDPLTHF--HQALSEPGSTYLHTDQYFNPRNVEAHAAGTGPEIVKDLDGRAP 177
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPD 243
D A+ ++E P ++ + S F G + V +G
Sbjct: 178 DWFVACVGTAGSSTGVARVLREHDPDVRVLGLVAHKS-DFIPGIRTIDEVHQVG------ 230
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNF---GAGK 300
+ D + D +E +A + ++++ G+L G + GAA A+R + + G+G+
Sbjct: 231 LFDPATYDTIESVTSGEALDGMLTLVRRCGILSGPTGGAAYQGAVRHLRDADSALDGSGR 290
Query: 301 R--VVVILPDGIRNYMT 315
R V I+ D +Y++
Sbjct: 291 RETAVFIVCDRAESYLS 307
>UniRef50_Q98PA8 Cluster: Cysteine synthase; n=2; Rhizobiales|Rep:
Cysteine synthase - Rhizobium loti (Mesorhizobium loti)
Length = 357
Score = 83.8 bits (198), Expect = 8e-15
Identities = 64/261 (24%), Positives = 112/261 (42%), Gaps = 6/261 (2%)
Query: 66 AQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEK-MSTISLLGAEV 124
A +G K+G+ +E TSG G+ VAL A + T+VT D K + + +GA V
Sbjct: 44 AASNGELKTGSHIVETTSGTFGMAVALLAAARDYRLTLVTASTLIDAKYRARLERIGATV 103
Query: 125 VQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVD 184
+ + L + L ++P+ QY + N Y AE ++ + VD
Sbjct: 104 IALDDPRGDGNQPGRLERLQEILAKEPDGFWTRQYDSPGN-WLAYARLAELLIRAIGKVD 162
Query: 185 MIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDV 244
+ A ++ P + VD S++FG+ P + G+G +P
Sbjct: 163 CLVGCVGTGGSLCGTASFLRTVFPHLTVFAVDTHRSILFGQ-PVGRRMLRGLGNSVLPKN 221
Query: 245 LDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVV 304
+ ++D++ Y A+ + ++++ GL G +SGAA + A A L +V V
Sbjct: 222 VRHELVDEIHWVGAYPAYMTAHRLLREHGLFMGPTSGAAALVAQWVATTL---PDAQVAV 278
Query: 305 ILPDGIRNYMTKFVCDQWMEA 325
I+PD + D+W+ A
Sbjct: 279 IMPDEGHRHAETVYNDEWLSA 299
>UniRef50_Q9LG24 Cluster: Cysteine synthase; n=4; core
eudicotyledons|Rep: Cysteine synthase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 439
Score = 82.6 bits (195), Expect = 2e-14
Identities = 40/109 (36%), Positives = 65/109 (59%), Gaps = 2/109 (1%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLEC--EMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
N +++ IG+TPL+R+N + + G E ++ KCEF+NPGGS+KDR++ ++ EA +SG
Sbjct: 42 NGLVDAIGNTPLIRINSLSEATGCEVFLDILGKCEFLNPGGSVKDRVAVKIIQEALESGK 101
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLL 120
G E ++G+T I +A G C +V PD + EK+ + L
Sbjct: 102 LFPGGIVTEGSAGSTAISLATVAPAYGCKCHVVIPDDAAIEKVISFKYL 150
Score = 53.6 bits (123), Expect = 1e-05
Identities = 49/180 (27%), Positives = 78/180 (43%), Gaps = 22/180 (12%)
Query: 157 DQYKNDVNPRTHYEYTAEEILALVP-DVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTV 215
DQ++N N R HYE T EI ++D ++ +++K + +
Sbjct: 239 DQFENLANYRAHYEGTGPEIWHQTQGNIDAFVAAAGTGGTLAGVSRFLQDKNERVKCFLI 298
Query: 216 DPQGSLIFG-------------EG-----PADLYFVEGIGGDFVPDVLDKSVIDKVEKPN 257
DP GS ++ EG P D EGIG + + + +D +
Sbjct: 299 DPPGSGLYNKVTRGVMYTREEAEGRRLKNPFDT-ITEGIGINRLTKNFLMAKLDGGFRGT 357
Query: 258 DYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKF 317
D +A MSR ++K +GL G SS + A+R A+ L G G +V IL D +++KF
Sbjct: 358 DKEAVEMSRFLLKNDGLFVGSSSAMNCVGAVRVAQTL--GPGHTIVTILCDSGMRHLSKF 415
>UniRef50_Q5YWN0 Cluster: Putative uncharacterized protein; n=1;
Nocardia farcinica|Rep: Putative uncharacterized protein
- Nocardia farcinica
Length = 441
Score = 82.2 bits (194), Expect = 2e-14
Identities = 79/295 (26%), Positives = 131/295 (44%), Gaps = 24/295 (8%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLE-CEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGI 71
Y++I + +G+TPL+RL+ P +GL+ E+FAK E NP GS+KDR++ + L + +
Sbjct: 3 YDHITDLVGNTPLLRLD--PAVHGLDGVELFAKLESHNPFGSVKDRVAVAL-LRDELDRV 59
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
G IE +SGNT + + A+ G G VT E + LLG E+V+ P ++
Sbjct: 60 RADGQTLIEASSGNTAKALRVLGAMSGVGLRAVTNRIKVGEVRDLLRLLGTEIVELPGLS 119
Query: 132 PWE---SSEHFLSVAKRRLLEDPNAI-SCDQYKNDVNPRTHYEYTAEEI---LAL--VPD 182
+ +V + + P A QY N+ N H+ T EI LA +
Sbjct: 120 ECPDPGAPNDVAAVIAATMAQAPGAYHHPSQYTNEKNIEAHWHGTGREIHRDLAARGIDR 179
Query: 183 VDMIXXXXXXXXXXXXXAQKVKEKCPKC-IIVTVDPQGSLIFG-EGPADLYFVEGIGGDF 240
VD + A ++ P I V + I G +++ V G F
Sbjct: 180 VDYLVGGLGTTGSTRGTATHLRTHHPGLRTIGVVSTRADFIPGIRSETEMWDV----GLF 235
Query: 241 VPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLN 295
P+ D++ + A + + G+L G +SGA+ +A+R + L+
Sbjct: 236 RPE-----FYDRILAVDSGTAIEATLHLATGYGVLAGPTSGASYAAALRTLRDLD 285
>UniRef50_Q59918 Cluster: Cysteine synthase (EC 2.5.1.47)
(O-acetylserine sulfhydrylase) (O- acetylserine
(Thiol)-lyase); n=49; Bacteria|Rep: Cysteine synthase
(EC 2.5.1.47) (O-acetylserine sulfhydrylase) (O-
acetylserine (Thiol)-lyase) - Staphylococcus
haemolyticus
Length = 155
Score = 82.2 bits (194), Expect = 2e-14
Identities = 42/113 (37%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
Query: 203 VKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAF 262
+KEK P IV ++P+ S + G + ++G+G FVPD L+ + D + + + A
Sbjct: 37 LKEKYPNIEIVAIEPEASPVLSGGEPGPHKLQGLGAGFVPDTLNTDIYDSIIQVGNDIAM 96
Query: 263 NMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMT 315
SR + K+EG+L G SSGAA+ +AI+ AK+L G GK V+ +LP Y++
Sbjct: 97 ETSRRVAKEEGILAGISSGAAIHAAIQKAKEL--GKGKTVLTVLPSNGERYLS 147
>UniRef50_A6FZP3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Plesiocystis pacifica SIR-1|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Plesiocystis pacifica SIR-1
Length = 369
Score = 81.8 bits (193), Expect = 3e-14
Identities = 69/277 (24%), Positives = 113/277 (40%), Gaps = 9/277 (3%)
Query: 38 ECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVC 97
ECE++A PG SIKD ++ ++ A+++G G IE TSG+ G+G+A A
Sbjct: 39 ECEIWAVLGGAQPGSSIKDLLAMGLLTLAREAGALAPGQALIESTSGSMGVGLAWAARCL 98
Query: 98 GFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLL-EDPNAISC 156
G T+V+ I GA ++ A P + + R LL P
Sbjct: 99 GHPLTLVSDPHIPALTRMKIEAHGATLITVDAPHPRGGWQQARAERVRALLAARPELYFV 158
Query: 157 DQYKNDVNPRTHYEYTAEEILALV--PDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVT 214
+Q + NP H + + V +D ++ + E P C
Sbjct: 159 EQNHSPFNPGAHARWLVPALARRVDPATIDAAVFVVGSGGHFSALSRWLVEANPSCRCFA 218
Query: 215 VDPQGSLIFGEGPADLYFVEGIG-GDFVPDVLDKSV--IDKVEKPNDYDAFNMSREIIKK 271
+ GS FG + G+G D VP V+ ++ + V D + R +++
Sbjct: 219 AERPGSRTFGAPRPGTSVLRGVGNSDIVPGVIARAFERVSGVVNVPDAHSLAACRRLLEA 278
Query: 272 EGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPD 308
LL G +SG A ++A A++L G V+ + PD
Sbjct: 279 HNLLVGPTSGLAYVAATALAQRLRRGV---VLTLFPD 312
>UniRef50_Q6L0G4 Cluster: Cysteine synthase; n=2;
Thermoplasmatales|Rep: Cysteine synthase - Picrophilus
torridus
Length = 254
Score = 80.6 bits (190), Expect = 8e-14
Identities = 78/262 (29%), Positives = 119/262 (45%), Gaps = 31/262 (11%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
IG+TPL+ L+ I +AK E+ N GSIKDR ++ M+ S + K G + I
Sbjct: 13 IGNTPLLNLDGI----------YAKAEYKNKFGSIKDRAAFFMI----SSVMDKIGNKII 58
Query: 80 -EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEH 138
E +SGNTGI VA + G IV P+ SD + +S +G + + TP S+E
Sbjct: 59 VEASSGNTGIAVAGISRELGIKSIIVIPEGASDGTKAMLSRIGVDYITTPG----NSTEQ 114
Query: 139 FLSVAKRRLLEDPNA-ISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXX 197
+ + + DP + +Q+ ND+N +HY TA EI + D I
Sbjct: 115 SIKYVENLIKSDPQKYLRLNQHSNDMNYLSHYMTTAPEIEHDMGKPDTIVIGIGTGGTIS 174
Query: 198 XXAQKVKEKCPKCIIVTVDP-QGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV--IDKVE 254
++ KEK ++ + P + S IFG L GI +DK++ ID V
Sbjct: 175 GISKYFKEKYHDVKVIGIIPDENSRIFGLRNPFLSVNHGI--------IDKNINYIDDVF 226
Query: 255 KPNDYDAFNMSREIIKKEGLLC 276
++ A E++ K L C
Sbjct: 227 IISEDAALKGVSELLSKYNLFC 248
>UniRef50_Q7UFE1 Cluster: Cysteine synthase B; n=3; Bacteria|Rep:
Cysteine synthase B - Rhodopirellula baltica
Length = 323
Score = 79.8 bits (188), Expect = 1e-13
Identities = 51/141 (36%), Positives = 75/141 (53%), Gaps = 4/141 (2%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
++ K E+ NP GS KDRI+ ++ +A +SG+ G +E +SG+T I +AL A G
Sbjct: 31 IWCKLEYHNPSGSTKDRIARFILGKAIRSGLLGRGDAVVEASSGSTSISLALMCAQFGLR 90
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYK 160
T V P S E++ I GAEV+ TPA E +++A + A + Q++
Sbjct: 91 FTAVMPRGVSSERIKMIRAFGAEVILTPAE---EGVGGAMALAD-EIAGRGEAFASKQFE 146
Query: 161 NDVNPRTHYEYTAEEILALVP 181
N NP H TA EI+A VP
Sbjct: 147 NPDNPAAHRYQTAAEIIAQVP 167
>UniRef50_A0G7W8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Burkholderia phymatum STM815|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Burkholderia phymatum STM815
Length = 547
Score = 79.8 bits (188), Expect = 1e-13
Identities = 63/252 (25%), Positives = 110/252 (43%), Gaps = 7/252 (2%)
Query: 65 EAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGA-- 122
+A G+ K G E +SG G+ +A+ + +++ S + LGA
Sbjct: 44 QAVSQGLLKPGATICESSSGTFGLALAMLAVQYDYNLILISDWAIDRHLKSRLVELGAHV 103
Query: 123 EVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD 182
E+V PA +A+ L E P + QY N NP + ++ AE ++ +
Sbjct: 104 EIVNDPAPQGGLQQARLNRLAQY-LREIPGSFWPSQYSNTGNPLAYGKF-AELLIKKLGK 161
Query: 183 VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVP 242
+D + + ++ P+ + VD S++FG+ DL + G+GG+ VP
Sbjct: 162 IDCLVGPVGSGGSMSGTTKFLRALFPELHAIGVDMPNSVLFGQPSGDLGDLSGLGGEIVP 221
Query: 243 DVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRV 302
+ D+V + F+ +R++ ++ GL G +SGAA A ++K GK V
Sbjct: 222 SNVAHQQFDEVHWLTPAEVFHGTRQLHREHGLFMGPTSGAAYRVADWWSRK---NRGKNV 278
Query: 303 VVILPDGIRNYM 314
V I PD Y+
Sbjct: 279 VAIFPDEGHRYV 290
>UniRef50_Q2W8G8 Cluster: Cysteine synthase; n=1; Magnetospirillum
magneticum AMB-1|Rep: Cysteine synthase -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 408
Score = 79.0 bits (186), Expect = 2e-13
Identities = 50/185 (27%), Positives = 88/185 (47%), Gaps = 9/185 (4%)
Query: 146 RLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXXXXXAQKVK 204
R+ + A DQ+ N NP H + T E+ + VD + ++
Sbjct: 86 RMAAETGAHFIDQFNNPANPAAHEDGTGPELWEQMGGRVDAVVAGAGSGGTLTGLSRFFA 145
Query: 205 EKCPKCIIVTVDPQGSLIFGE------GPADLYFVEGIGGDFVPDVLDKSVIDKVEKPND 258
+ P +V DP+GS++ G A + VEGIGGD +P V D S + + +D
Sbjct: 146 RRSPATEMVLADPRGSVLADYVRTGRVGEAGSWLVEGIGGDSIPMVSDFSRVTRAYSVSD 205
Query: 259 YDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKFV 318
++F +R +++ EGLL G SSG + +A+R ++ A KRV ++ D ++++
Sbjct: 206 RESFATARLVLRIEGLLVGSSSGTLLAAALRYCREQT--APKRVATLVCDAGNRHLSRLH 263
Query: 319 CDQWM 323
+ W+
Sbjct: 264 DESWL 268
>UniRef50_A6YEH3 Cluster: CmnB; n=1; Saccharothrix mutabilis subsp.
capreolus|Rep: CmnB - Streptomyces capreolus
Length = 362
Score = 79.0 bits (186), Expect = 2e-13
Identities = 74/287 (25%), Positives = 116/287 (40%), Gaps = 7/287 (2%)
Query: 6 SFTRNRIYNNILETIGDTPLVRLNRIPKDY-GLECEMFAKCEFVNPGGSIKDRISYTMVL 64
S T + ++ + P V + R+ + G+ + K E +P SIK R + +V
Sbjct: 12 STTAAEVLEHVDAAVAAYPEVPIARVRVEVAGIPRTLLLKLEGRSPWRSIKGRTALGLVR 71
Query: 65 EAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGA-- 122
+A +E TSGN G+ ++ G V K S + I GA
Sbjct: 72 SIAPR-MASRDVTVVESTSGNLGVALSAICRDLGLPFVAVVDLKQSPVIQAAIEANGARL 130
Query: 123 EVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALV-P 181
EVV+TPA A + L ++ + E P A+ +QY+ND N H +TA EI V
Sbjct: 131 EVVRTPAAATTHLLDR-LDRVRKLVAEIPGAVWPNQYENDANRHVHETWTAPEIDRQVGG 189
Query: 182 DVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFV 241
+ + A + P +V VD +GS +FG P + GIG
Sbjct: 190 EAQAVFVAVSTGGTLAGLAAHFRRARPATRLVAVDVEGSTVFGGVPGG-RVLTGIGASRR 248
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAI 288
L ++ D + + A + G+ GGSSGA + A+
Sbjct: 249 STFLTRAECDDLVYVREAAAIAACHVLRADTGIAVGGSSGAVVAGAL 295
>UniRef50_UPI0000ECD4F3 Cluster: UPI0000ECD4F3 related cluster; n=1;
Gallus gallus|Rep: UPI0000ECD4F3 UniRef100 entry -
Gallus gallus
Length = 163
Score = 77.8 bits (183), Expect = 5e-13
Identities = 44/106 (41%), Positives = 61/106 (57%), Gaps = 10/106 (9%)
Query: 154 ISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXXXXXAQKVKEKCPKCII 212
I+ +Y+N NP HY+ TAEEIL V M+ A+K+KEKCP+C I
Sbjct: 58 IAYQRYRNPSNPLAHYDTTAEEILEQCEGKVHMVVIGSGTGGTVTGVARKLKEKCPECKI 117
Query: 213 VTVDPQGSLIFGEGPADL-------YFVEGIGGDFVPDVLDKSVID 251
+ VDP+GS++ P++L VEGIG DF+P VLD+S +D
Sbjct: 118 IGVDPEGSIV--ALPSELNRTNNITVEVEGIGHDFIPTVLDRSALD 161
>UniRef50_A2BN44 Cluster: Cysteine synthase; n=3; Thermoprotei|Rep:
Cysteine synthase - Hyperthermus butylicus (strain DSM
5456 / JCM 9403)
Length = 406
Score = 77.8 bits (183), Expect = 5e-13
Identities = 57/170 (33%), Positives = 85/170 (50%), Gaps = 14/170 (8%)
Query: 11 RIYNNILETI---GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGG-SIKDRISYTMVLEA 66
R++ + LE + TPLVRL + D ++AK E+ NP S+KDRI + M++ A
Sbjct: 99 RVFKSSLELLYRNWPTPLVRLESLSTD---GYRVWAKLEWYNPYSMSVKDRIGWYMIVRA 155
Query: 67 QKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQ 126
++G G E TS NTG+ +A A+ GF + P + LGAEV++
Sbjct: 156 LETGWR--GREVYETTSTNTGMALAAMGAIHGFRVKLWIPKTIQKASDVLLKALGAEVIR 213
Query: 127 TPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI 176
T + E + AKR NA+ DQ+ ND N H +YTA+E+
Sbjct: 214 TDKQLTVDLIEDVKTEAKR-----SNALHVDQFNNDANFLVHLKYTAKEL 258
>UniRef50_Q980F2 Cluster: Cysteine synthase B; n=4;
Sulfolobaceae|Rep: Cysteine synthase B - Sulfolobus
solfataricus
Length = 297
Score = 77.4 bits (182), Expect = 7e-13
Identities = 84/305 (27%), Positives = 136/305 (44%), Gaps = 37/305 (12%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNP-GGSIKDRISYTMVLEAQKSGIAKS 74
+LE + TPL++L RI D +AK EF NP S+KDR ++ + +A + K+
Sbjct: 14 LLEGMWPTPLLKL-RIGND------TWAKLEFYNPFSRSVKDRTAWFLFRQA----LLKN 62
Query: 75 GTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWE 134
T +E TSGNTGI +A +++ G T+ P + LLG V++
Sbjct: 63 ATHIVEATSGNTGIALASLSSIFGMRFTMFLPVVAPKVYKVFVKLLGGNVIEA-----GN 117
Query: 135 SSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDV----DMIXXXX 190
S+ + + K + E NA++ DQ+ N +N HYE TA EI + + I
Sbjct: 118 STNDVIPLVK-KFAEMTNALNLDQFNNPINVIAHYETTAREIDEQLSSIGKKPSRIIATM 176
Query: 191 XXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSV- 249
A+ KEK + I G P++ + GI + L + V
Sbjct: 177 GTGGHIAGIAKYFKEKYGNDV---------EIIGVQPSENSRIPGIKRQNGSNSLLRDVK 227
Query: 250 IDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDG 309
ID+V + +A + + + + G+L G S+GA + A KK++ V+I PD
Sbjct: 228 IDRVVDVSLEEAIDGTISVARTSGILIGISAGA----TVAAYKKIS-DVSSTTVLIFPDD 282
Query: 310 IRNYM 314
Y+
Sbjct: 283 AFKYV 287
>UniRef50_Q3JSA1 Cluster: Cysteine synthase; n=6; Burkholderia
pseudomallei|Rep: Cysteine synthase - Burkholderia
pseudomallei (strain 1710b)
Length = 375
Score = 76.2 bits (179), Expect = 2e-12
Identities = 69/266 (25%), Positives = 113/266 (42%), Gaps = 11/266 (4%)
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMST-ISLL 120
++ A SG G +E +SG +G+ + A IV+ D DE++ + L
Sbjct: 52 IIENAIASGQLNPGMPVLETSSGTFAMGIGIVCAEKRIPFHIVS-DAAIDERLQARLRQL 110
Query: 121 GAEVVQTPAMAPWESSEHF-LSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILAL 179
G V A A + + L + RL E+P QY N N + + A+ I
Sbjct: 111 GGRVQIVGANATGSNVQVLRLEALQERLRENPGGFWPRQYDNPDNQHAYRAFAAQLIRTF 170
Query: 180 VPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGD 239
++ ++ + ++E P +V VD GS++FG P + G+G
Sbjct: 171 GTNLTIVGTVGSGASTCGTI-RALREVDPSIPLVGVDTFGSVLFGL-PVGPRALRGLGNS 228
Query: 240 FVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISA--IRAAKKLNFG 297
P+ LD + D+V AF +R + ++ GL CG +SGAA + A +RA +
Sbjct: 229 IYPNNLDHTCFDQVHWVAPDAAFGSTRRLHRQHGLYCGPTSGAAFMVAEWLRAQR----D 284
Query: 298 AGKRVVVILPDGIRNYMTKFVCDQWM 323
G+ +V I PD Y D W+
Sbjct: 285 DGRTIVFIAPDEGHRYADTVYDDAWL 310
>UniRef50_Q97B69 Cluster: Cysteine synthase; n=2; Thermoplasma|Rep:
Cysteine synthase - Thermoplasma volcanium
Length = 309
Score = 74.5 bits (175), Expect = 5e-12
Identities = 71/274 (25%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
++AK E+ N GSIKDR ++ +++ KS G +E +SGNTG+ ++ +++ G
Sbjct: 37 IYAKIEWENRFGSIKDRPAF-FIMDYLKSKGVLEGKAIVEASSGNTGLAISTISSMLGLQ 95
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYK 160
IV P+ S I G++++ TP P +E + A R L + +Q+
Sbjct: 96 SCIVLPENASQATKKIIVENGSQLILTP---PDLGTEGSIEKA-RSLASSGSFYWINQHS 151
Query: 161 NDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGS 220
N +N HY TA E+L + I A+ KE+ P ++ V P
Sbjct: 152 NPLNSDVHYYSTAPELLDQEGMPEAIVAGVGTGGTITGIARYFKERDPSVKVIGVQPS-- 209
Query: 221 LIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSS 280
++ P L ++ + D L S ID + DA + G L G SS
Sbjct: 210 -LYSHIPG-LRDIKKTSNKGLID-LYGSYIDDFLYVKESDAIAEVFDHYVNTGELIGISS 266
Query: 281 GAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYM 314
GA + ++ + + K K++ + PD R Y+
Sbjct: 267 GANLYASKQLSSKF-----KKIFTVFPDSGRKYL 295
>UniRef50_Q2RGZ3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Moorella thermoacetica ATCC
39073|Rep: Pyridoxal-5'-phosphate-dependent enzyme, beta
subunit - Moorella thermoacetica (strain ATCC 39073)
Length = 452
Score = 72.5 bits (170), Expect = 2e-11
Identities = 69/286 (24%), Positives = 114/286 (39%), Gaps = 26/286 (9%)
Query: 50 PGGSIKDRISYTMVLEAQKSGIAKSGTRFI-EPTSGNTGIGVALATAVCGFGCTIVTPDK 108
P GS K +Y ++E G+ K G I P++GN GIGVA + + GF ++ PD
Sbjct: 79 PSGSHKVGPAYATLIEGCVDGVIKPGEHTILGPSTGNFGIGVAYISRLLGFRAIVIMPDN 138
Query: 109 NSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKR-RLLEDPNAISCDQYKNDVNPRT 167
S E+ I G E+ TP S+ L++ + L +DP + Q++ N R
Sbjct: 139 MSKERYERIRKYGGELDLTPG----TESDVILTLQRTYELKKDPKNFALAQFELLPNYRF 194
Query: 168 HYEYTAEEILALVPDVD----MIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF 223
H T + V + ++K+ P+C + ++P
Sbjct: 195 HRHVTGNAAIEAVQGIGNGRIAAFTSAPGSAGTLGAGDQIKKVFPECKVAALEPYECSTL 254
Query: 224 GEGPADLYFVEGIGG------------DFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKK 271
G + +EGIG DF+ + D+ + ++ D + + +
Sbjct: 255 YNGGRGQHRIEGIGDKMCTLIHNVLNTDFIVLIHDEDTVRGLKVFQDGTETLIKMGVKEA 314
Query: 272 EGLLCG---GSSGAA-MISAIRAAKKLNFGAGKRVVVILPDGIRNY 313
+ L G SG ++ AI+ AK L G G VV + DG Y
Sbjct: 315 DALALRDNFGPSGICNILGAIKIAKYLRLGPGDNVVTVATDGFDRY 360
>UniRef50_A3KFG2 Cluster: DabA; n=1; Actinoplanes friuliensis|Rep:
DabA - Actinoplanes friuliensis
Length = 357
Score = 72.5 bits (170), Expect = 2e-11
Identities = 66/263 (25%), Positives = 112/263 (42%), Gaps = 8/263 (3%)
Query: 66 AQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGA--E 123
A + G + T +E TSG G+ +A+ +A+ +V+ ++ LGA E
Sbjct: 47 AIERGELEPDTAVVETTSGTFGLALAMQSALLERELILVSDPAIDVHLHRRLNDLGAQVE 106
Query: 124 VVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDV 183
+ + PA +A+ R E +QY N NPR+ Y A+++ + V
Sbjct: 107 ICRDPAPVGGYQRSRLDRLAEVRA-ERERTFCPEQYTNPDNPRS-YGVVADQLARTLGQV 164
Query: 184 DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIGGDFVPD 243
D + + ++ P + VD S++FG+ P + G+G P+
Sbjct: 165 DAVIGPVGSGGSMCGTVRGLRATTPHTRAIGVDTHHSVLFGQ-PDGHRSLRGLGNSLWPE 223
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVV 303
LD SV D V +A+ +R + + L G +SGAA + A A++ G+ V
Sbjct: 224 NLDHSVFDDVHWCTAGEAYAATRRLHGRHALYQGPTSGAAYLVADWYARR---NPGELCV 280
Query: 304 VILPDGIRNYMTKFVCDQWMEAH 326
V+LPD Y D W+ A+
Sbjct: 281 VMLPDEGYRYQATAYDDGWLAAN 303
>UniRef50_Q62J64 Cluster: Cysteine synthase/cystathionine
beta-synthase family protein; n=14; Burkholderia|Rep:
Cysteine synthase/cystathionine beta-synthase family
protein - Burkholderia mallei (Pseudomonas mallei)
Length = 336
Score = 67.7 bits (158), Expect = 6e-10
Identities = 66/270 (24%), Positives = 118/270 (43%), Gaps = 14/270 (5%)
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
++ +A + G T +E +SGN +G+A+ G IV + + LG
Sbjct: 29 IIEQALRDGRIDRDTLVVESSSGNFALGLAVVCREQGLKLRIVGDPAIDPKLRGMLHNLG 88
Query: 122 AEV--VQTP-AMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL- 177
AEV ++ P A+ ++ L+ + L PNA QY N NP Y AE +L
Sbjct: 89 AEVDIIEKPDALGAYQRLR--LARVAQLLGAHPNAFWVQQYDNPGNPDA-YRPLAERLLD 145
Query: 178 ALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIG 237
+ P D++ A ++ + + VD S++FG P + G+G
Sbjct: 146 EMGPAFDLV-ACVGSGGSSVGLATHLRRHSEQVRVTGVDTFNSVLFGL-PDGKRTLRGLG 203
Query: 238 GDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAA-MISAIRAAKKLNF 296
+P +LD + D++ A + E+ + GL CG +SGAA I++ +AA++
Sbjct: 204 NSIMPKILDHTQFDEIHWLASPQANLAAIELHARHGLFCGPTSGAAYRIASHQAARQ--- 260
Query: 297 GAGKRVVVILPDGIRNYMTKFVCDQWMEAH 326
++ + + PD Y +W++A+
Sbjct: 261 -PARKTLFVAPDTGYRYQDTIFDARWLKAN 289
>UniRef50_A2R0U9 Cluster: Catalytic activity: O3-acetyl-L-serine +
hydrogen sulfide = L-cysteine + acetate; n=1;
Aspergillus niger|Rep: Catalytic activity:
O3-acetyl-L-serine + hydrogen sulfide = L-cysteine +
acetate - Aspergillus niger
Length = 309
Score = 67.7 bits (158), Expect = 6e-10
Identities = 54/203 (26%), Positives = 89/203 (43%), Gaps = 5/203 (2%)
Query: 113 KMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNP-RTHYEY 171
K S+ L E+V T + + H S + L + N I + ++ +NP T E
Sbjct: 103 KYSSFLLENPEIVSTRSYPT--AQNHAFSASSCGLWIEGNIIEEAERRSTLNPGMTVVEA 160
Query: 172 TAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLY 231
T + + + + + P +V ++P S + EG +
Sbjct: 161 TGGSTGSSLAFISRQRDTDSECRYGYGSIMRSEVYVPDTRVVVLEPASSPVITEGRTGSH 220
Query: 232 FVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAA 291
VEGIG FVP LD + D+ ++ + M R + ++EGL+ G S+G +++AI A
Sbjct: 221 SVEGIGNGFVPPHLDPKLYDEARGISEREGRAMCRRLAREEGLVVGTSTGLNVVAAIALA 280
Query: 292 KKLNFGAGKRVVVILPDGIRNYM 314
K+L G GK VV + D YM
Sbjct: 281 KEL--GPGKTVVTVAVDTGLRYM 301
>UniRef50_Q6WZB1 Cluster: 2,3-diaminopropionate synthase; n=2;
Streptomyces vinaceus|Rep: 2,3-diaminopropionate
synthase - Streptomyces vinaceus
Length = 346
Score = 67.3 bits (157), Expect = 7e-10
Identities = 67/257 (26%), Positives = 102/257 (39%), Gaps = 8/257 (3%)
Query: 36 GLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATA 95
G+ + K E +P S+K R + +++ A T +E TSGN G+ ++
Sbjct: 18 GIPRTITLKLEGHSPWRSVKGRTALSLIRSVAGDLTAPDAT-VVESTSGNLGLALSAICR 76
Query: 96 VCGFGCTIVTPDKNSDEKMSTISLLGAEV--VQTPAMAPWESSEHFLSVAKRRLLED-PN 152
G V + S I G E+ V+TP A + V R L D P+
Sbjct: 77 DLGLRFIAVVDHRQSPVIQQAIEANGGELDWVRTPDDATTHLQDRLARV--RELERDLPH 134
Query: 153 AISCDQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXXXXXAQKVKEKCPKCI 211
A+ +QY+ND N R H +TA E A V + ++ + P
Sbjct: 135 AVWPNQYENDANWRIHETWTAPEFDAQVTHRAQALFAGVSTGGTLAGLSRHFRRTRPGLR 194
Query: 212 IVTVDPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKK 271
IV VD +GS +FG P + GIG L ++ D V ++ A +
Sbjct: 195 IVAVDVRGSTVFGGVPRP-RTLTGIGAGRRSAFLTRASTDDVLLVDERQAVACCHTLRAD 253
Query: 272 EGLLCGGSSGAAMISAI 288
G GGSSGA + +
Sbjct: 254 TGTAVGGSSGAVLAGCL 270
>UniRef50_Q0D1N1 Cluster: Cysteine synthase 2; n=4;
Eurotiomycetidae|Rep: Cysteine synthase 2 - Aspergillus
terreus (strain NIH 2624)
Length = 446
Score = 65.3 bits (152), Expect = 3e-09
Identities = 50/181 (27%), Positives = 80/181 (44%), Gaps = 22/181 (12%)
Query: 157 DQYKNDVNPRTHYEYTAEEILALVPD-VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTV 215
DQ++N+ N R HY T EI A +D A +K + P +V
Sbjct: 246 DQFENEANWRAHYSATGPEIYAQCNGALDAFVAGAGTGGTISGVALFLKPRIPNLRVVLA 305
Query: 216 DPQGSLIFGEGPADLYF-----------------VEGIGGDFVPDVLD--KSVIDKVEKP 256
DPQGS ++ + F VEGIG + V + K ++D +
Sbjct: 306 DPQGSGLYNRVRYGVMFDVKEREGTRRRRQVDTIVEGIGINRVTANFEVGKELVDDAVRV 365
Query: 257 NDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTK 316
D A M+R +++K+G+ G SS +A++ A KL G G R+V +L D ++++
Sbjct: 366 TDAQALAMARWLVEKDGIFLGSSSAVNCFAAVKTAMKL--GPGHRIVTVLSDSGSRHLSR 423
Query: 317 F 317
F
Sbjct: 424 F 424
Score = 56.0 bits (129), Expect = 2e-06
Identities = 35/91 (38%), Positives = 51/91 (56%), Gaps = 5/91 (5%)
Query: 12 IYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGG-SIKDRISYTMVLEAQKSG 70
I + I IG+TPL R+ + + G CE+ K EF+N G S KDR++ +M+ A++ G
Sbjct: 64 IVDGIEGCIGNTPLFRIKSLSEATG--CEILGKAEFLNGAGQSSKDRVALSMIEIAEELG 121
Query: 71 IAK--SGTRFIEPTSGNTGIGVALATAVCGF 99
I SG E TSG+TGI +A G+
Sbjct: 122 ILTPHSGDTIYEGTSGSTGISLATLARAKGY 152
>UniRef50_A1D9N4 Cluster: Cysteine synthase B, putative; n=3;
Pezizomycotina|Rep: Cysteine synthase B, putative -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 526
Score = 65.3 bits (152), Expect = 3e-09
Identities = 66/302 (21%), Positives = 135/302 (44%), Gaps = 21/302 (6%)
Query: 24 PLVRLNRIPKDYGLE-CEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
PLV + Y + ++AK ++P ++K + M+ + G K+ IE +
Sbjct: 28 PLVEVPEYLNPYHQDGVRIYAKMMSMHPANNVKAMPALNMLEKKVVPGKTKT---IIEYS 84
Query: 83 SGNTGIGVALATAVC-GFGCT-IVTPDKNSDEKMSTISLLGAEVVQT--PAMAPWESSEH 138
SG+T I +++ V G T +K SD K+ + G ++ P+
Sbjct: 85 SGSTVISMSMIARVMHGIHDTRAFLSNKTSDAKLKLMQFFGLDITLFGGPSQPEPFDDRG 144
Query: 139 FLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXX 198
+ A++ LE ++ +QY+N+ N +H +T +IL +P+++++
Sbjct: 145 GIQRARKMGLESDEILNPNQYENNDNWGSHVRWTGPQILKQLPEINVLCAGMGTSGTMTG 204
Query: 199 XAQKVKEKCPKCIIVTV-DPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPN 257
KE P + + V G + GP L ++ + + + +D +E+ N
Sbjct: 205 LGTFFKENKPSVLRLGVCTAAGDRV--PGPRSLALLKPVEFPW------REAVDAIEEVN 256
Query: 258 DYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDGIRNYMTKF 317
+D+F++S ++ +EG++CG SSG + + ++ AG + PDG+ + + F
Sbjct: 257 SFDSFSLSLDLC-REGIVCGPSSGFNLQGLFQLLERRK-QAGTLAELAGPDGLVHCV--F 312
Query: 318 VC 319
+C
Sbjct: 313 IC 314
>UniRef50_A3ZYZ6 Cluster: Threonine synthase; n=2;
Planctomycetaceae|Rep: Threonine synthase -
Blastopirellula marina DSM 3645
Length = 353
Score = 64.9 bits (151), Expect = 4e-09
Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 5/104 (4%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G+TPLVR RI GL+ ++ K E VNP GS KDR + + + Q+ G R I
Sbjct: 9 GNTPLVRSQRIGPALGLK-NLYFKLETVNPTGSYKDRFAAAAIADMQRQG----KRRVIA 63
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
+SGNTG +A A G CTI D K+ + GA++
Sbjct: 64 TSSGNTGSALAAYAAAAGMACTIAIVDGAPAGKLRQMMAYGADI 107
>UniRef50_Q981U9 Cluster: Cysteine synthase; n=2; Mesorhizobium
loti|Rep: Cysteine synthase - Rhizobium loti
(Mesorhizobium loti)
Length = 351
Score = 64.1 bits (149), Expect = 7e-09
Identities = 62/266 (23%), Positives = 116/266 (43%), Gaps = 11/266 (4%)
Query: 62 MVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
++ +A G G + +E +SG +G+A+ GF I T + ++ LG
Sbjct: 45 IIEQALAQGTLTHGMKVLETSSGTFALGLAVVCRERGFQLEIFTDPVMDRGLENRLTSLG 104
Query: 122 AEV---VQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA 178
AEV + ++ S A+ R L + QY+ NP Y+ A++I
Sbjct: 105 AEVCIITEKAREGGYQRSRLDALHARMRQL-GHSCFWPRQYETPDNPAA-YKLFADQISG 162
Query: 179 LVPDVDM-IXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYFVEGIG 237
++ D D+ + +++++K P ++ VD S+IFG+ + + G+G
Sbjct: 163 ML-DADVTLVGSVGSGGSTCGTIERLRQKAPGARLIGVDTFNSVIFGQQDGERK-LRGLG 220
Query: 238 GDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFG 297
VP + + D+V + AF +R + ++ + G +SGA+ I A++
Sbjct: 221 NSLVPKNVKHELYDEVHLISAPLAFAATRTLHERHAVFAGPTSGASYIVGRWRARQY--- 277
Query: 298 AGKRVVVILPDGIRNYMTKFVCDQWM 323
G+ VVVI PD Y+ +W+
Sbjct: 278 PGETVVVICPDEGHRYVETAYDHEWL 303
>UniRef50_A6LNR7 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Thermosipho melanesiensis BI429|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Thermosipho melanesiensis BI429
Length = 470
Score = 62.9 bits (146), Expect = 2e-08
Identities = 68/289 (23%), Positives = 115/289 (39%), Gaps = 27/289 (9%)
Query: 50 PGGSIKDRISYTMVLEAQKSG-IAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDK 108
P GS K +Y+++ E +G + I P++GN GIG A ++ + ++ P++
Sbjct: 78 PSGSHKVGATYSILAEKTVNGEVDPFKHTLIWPSTGNYGIGGAWVSSRMNYKSIVILPEE 137
Query: 109 NSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAIS-CDQYKNDVNPRT 167
S E+ I GAEVV T + + AK ++P + +Q++ N R
Sbjct: 138 MSKERFEIIKKYGAEVVATTGCE--SNVKEIYDKAKELYQKNPEYVRILNQFEEFGNYRF 195
Query: 168 HYEYTAEEILALVPDVDM------IXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSL 221
HY T ++ LV + +VK+K P +V V+P
Sbjct: 196 HYYVTGNTMIDLVKKEKIGNQKISAVVLGVGSAGTIASGDRVKQKFPTAKVVAVEPLQCP 255
Query: 222 IFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLC----- 276
+ ++GIG V + + D + +D DA M + + EG+
Sbjct: 256 TISLNGYGAHDIQGIGDKHVTWIHNVLNNDAIVLVDDLDAKKMLQVLTDPEGIKFLKEFI 315
Query: 277 -----------GGSSGAA-MISAIRAAKKLNFGAGKRVVVILPDGIRNY 313
G SG A +I+AI+ AK NF + ++ D I Y
Sbjct: 316 PKDEIDFISDKFGISGVANLIAAIKIAKYYNFNNNDNIFIVATDSIDRY 364
>UniRef50_Q8CZI2 Cluster: Cysteine synthase; n=9; Bacteria|Rep:
Cysteine synthase - Yersinia pestis
Length = 335
Score = 62.5 bits (145), Expect = 2e-08
Identities = 72/311 (23%), Positives = 127/311 (40%), Gaps = 28/311 (9%)
Query: 17 LETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGT 76
L+ IG+T L+ L + + +F+KCEF NP GS KDR ++ ++ G
Sbjct: 24 LKDIGNTELIELKNLSINNN---SLFSKCEFNNPTGSHKDRTFLHILNILEEENKIIPGM 80
Query: 77 RFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESS 136
I+ ++GN G +A G+ I P+ ++E+ I G E+++TP
Sbjct: 81 TLIDCSTGNGGAALAWIGQKKGYKIKIFMPEGMTEERKEQIYSFGGEIIETP-------K 133
Query: 137 EHFLSVAKRRLLE----DPNAISCDQYKNDVNPRTHYEYTAEEILALVPDV----DMIXX 188
E+FL A + E N +Q +N + + EEI+ + ++ D
Sbjct: 134 ENFLKGAVKAATEYSNHQKNIFFLNQSDTTLN-KDAWHSCGEEIVRKMKEINKKPDYFIC 192
Query: 189 XXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPADLYF------VEGIGGDFVP 242
A+ +K+ P+ V ++ S L F + G+G +
Sbjct: 193 SIGTGGTFSGIAEILKKAYPRIHTVGIEVDQSAPIYSQRHGLNFHHKHHNLMGLGAGVIS 252
Query: 243 DVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRV 302
+ID+V N A+ + I+KE L G + GA ++ +++N GK +
Sbjct: 253 VNTLLDLIDEVRVVNGKAAWERMKSFIEKERLGIGPTCGANLLITEDIMQEVN---GKVI 309
Query: 303 VVILPDGIRNY 313
V + D Y
Sbjct: 310 VTLFFDSAWKY 320
>UniRef50_Q60B84 Cluster: Threonine synthase; n=7;
Gammaproteobacteria|Rep: Threonine synthase -
Methylococcus capsulatus
Length = 380
Score = 58.4 bits (135), Expect = 3e-07
Identities = 37/107 (34%), Positives = 54/107 (50%), Gaps = 5/107 (4%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
GDTPL+RL IP+ G E++ K E +NP GS KDR TM A + + I
Sbjct: 32 GDTPLIRLENIPRLLGRRVELYVKYEGLNPTGSFKDR-GMTM---AVTRAVEEGSRAIIC 87
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPD-KNSDEKMSTISLLGAEVVQ 126
++GNT A A G ++ PD K + K++ + G+ V+Q
Sbjct: 88 ASTGNTSAAAAAYAARAGITAFVLIPDGKIAMGKLAQAMMYGSVVIQ 134
>UniRef50_Q0UAH5 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 472
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/269 (23%), Positives = 121/269 (44%), Gaps = 23/269 (8%)
Query: 24 PLVRLNRIPKDYGLE-CEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
PLV + + Y + +FAK ++P ++K + M+ + + G K+ +E +
Sbjct: 29 PLVEVPQTLNPYYQDGVRIFAKMMSMHPANNVKIMPAMNMLEKGVQQGKTKT---VVEYS 85
Query: 83 SGNTGIGVALATAVCGF--GCTIVTPDKNSDEKMSTISLLGAEV-VQTPAMAPWESSEHF 139
SG+T I +ALA+ V +K + K+ + G +V V + + S
Sbjct: 86 SGSTVISLALASRVYHQIQDVRAFLSNKTTTPKLRLMQFFGLDVWVLSNTLFGGPSQPEP 145
Query: 140 LS----VAKRRLL--EDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXX 193
L + + RLL ED ++ +QY+ND N ++H ++T +I +P+++++
Sbjct: 146 LDERGGIHRARLLAQEDEQVLNANQYENDGNWQSHVKWTGPQIHKQLPNINVLCAGMGTS 205
Query: 194 XXXXXXAQKVKEKCPKCIIVTV-DPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDK 252
Q K+ P + V G + GP + + + + +D
Sbjct: 206 GTMTGLGQYFKQAKPSVTRLGVCTAAGDRV--PGPRSYALLAPVEFPW------RDSVDA 257
Query: 253 VEKPNDYDAFNMSREIIKKEGLLCGGSSG 281
VE+ DAF++S ++ +EGL+CG SSG
Sbjct: 258 VEEVGSKDAFSLSLQLC-REGLVCGPSSG 285
>UniRef50_Q58860 Cluster: Probable threonine synthase; n=19;
Archaea|Rep: Probable threonine synthase - Methanococcus
jannaschii
Length = 405
Score = 56.4 bits (130), Expect = 1e-06
Identities = 41/136 (30%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPL R N + K+ G++ E++ K E NP GS KDR V A + G+ G
Sbjct: 73 GGTPLYRCNNLEKELGIK-ELYVKNEGANPTGSFKDRGMTVGVTRANELGVEVVGC---- 127
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPD-KNSDEKMSTISLLGAEVVQTPAMAPWESSEHF 139
++GNT +A +A G C ++ P+ K + K++ GA+V+Q ++ +
Sbjct: 128 ASTGNTSASLAAYSARSGKKCIVLLPEGKVALGKLAQAMFYGAKVIQVKGNFD-DALDMV 186
Query: 140 LSVAKRRLLEDPNAIS 155
+AK +L+ N+I+
Sbjct: 187 KQLAKEKLIYLLNSIN 202
>UniRef50_Q0C2B7 Cluster: Pyridoxal-phosphate-dependent enzyme; n=1;
Hyphomonas neptunium ATCC 15444|Rep:
Pyridoxal-phosphate-dependent enzyme - Hyphomonas
neptunium (strain ATCC 15444)
Length = 338
Score = 56.0 bits (129), Expect = 2e-06
Identities = 54/206 (26%), Positives = 84/206 (40%), Gaps = 10/206 (4%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGT--R 77
IG+TPL + G+ E+ K E N GS+KDR+++ ++ + IA+ G
Sbjct: 14 IGNTPLTPFSITLN--GIRHELLLKEERCNAFGSVKDRVAWYILSQT----IAEKGPVEA 67
Query: 78 FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSE 137
++ +SGN G +A G TIV+ S I GA +V AP E S
Sbjct: 68 VVDASSGNYGYALASICQEMGIAATIVSSSSISAFNAEGIKRAGARLVIAEP-APGECSN 126
Query: 138 HFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXX 197
+ +QY N +NP +H +TA E+ A P D
Sbjct: 127 AARMRVAGEISAAEGQTFLNQYANFMNPASHEHWTAPEVFADGP-FDACFVTSSSGGTAR 185
Query: 198 XXAQKVKEKCPKCIIVTVDPQGSLIF 223
+ +K + +V V+P+ S F
Sbjct: 186 GFSDYLKAERNGTQLVLVEPEASSAF 211
>UniRef50_A2BKW1 Cluster: Threonine synthase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Threonine synthase -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 366
Score = 56.0 bits (129), Expect = 2e-06
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
+F K E++NP GS KDR + + A + G +E TSGNTGI VA A G
Sbjct: 82 VFFKLEYLNPTGSFKDRGTSLALAYASRMGFRL----VVEDTSGNTGISVAAYAAAYGLR 137
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
I P + K + LG EVV TP+
Sbjct: 138 ARIYMPVNAPEGKKRLVRALGGEVVLTPS 166
>UniRef50_A6NZW4 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 416
Score = 55.6 bits (128), Expect = 2e-06
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G+TPL++L R+ + G+E ++ K E NP S KDR+ ++ +A+ G+
Sbjct: 78 GNTPLLKLERLGEKLGIE-NLYVKDESRNPTMSYKDRLCSVIITKARHDGVPA----VTM 132
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
++GN G A A G C I T + D + + GA+V+ TP
Sbjct: 133 ASTGNHGAAAAAYAAAAGMPCVIFTIPQVPDTMKTLMQAYGAKVIVTP 180
>UniRef50_Q5KGT7 Cluster: Serine family amino acid
catabolism-related protein, putative; n=4; Dikarya|Rep:
Serine family amino acid catabolism-related protein,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 331
Score = 55.6 bits (128), Expect = 2e-06
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
TPLVR + K G CE+ K E + P GS K R +VL++ S + F +
Sbjct: 19 TPLVRSAALSKLAG--CEILLKLENIQPSGSFKSRGIGNLVLQSVNSAPPDTPLHFYSSS 76
Query: 83 SGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGA-EVVQTPAMAPWESSEHFLS 141
GN G+ A + G+ +++ P + + GA EV+QT +E+ +H
Sbjct: 77 GGNAGLACVNAASTLGYPSSVIVPLSTKPFMIDKLRTAGATEVIQT-GQTWFEADKH--- 132
Query: 142 VAKRRLLEDPNAI 154
+ + L DPN I
Sbjct: 133 LQEEILARDPNGI 145
>UniRef50_A6R3N4 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 431
Score = 55.6 bits (128), Expect = 2e-06
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Query: 22 DTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLE-AQKSGIAKSGTRFIE 80
+TPLV + + G C +F K E + PGGS K R ++L + F
Sbjct: 21 ETPLVESEPLSRLAG--CRIFLKLENLQPGGSFKSRAMGNLILHHLSRPANHNKNLHFFI 78
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVV 125
P+ GN GI A G+ CT+V P S + + GA V
Sbjct: 79 PSGGNAGIAAVTAARALGYPCTVVVPTYTSPMMLQRLQAAGAITV 123
>UniRef50_Q0W7Y3 Cluster: Threonine synthase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Threonine synthase -
Uncultured methanogenic archaeon RC-I
Length = 413
Score = 55.2 bits (127), Expect = 3e-06
Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 3/108 (2%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQK--SGIAKSGTRF 78
G TPLVR I ++ G E+F K E +NP GS KDR S + +A +
Sbjct: 76 GGTPLVRSRNIAREPGFG-ELFFKLESLNPTGSFKDRGSTVEISQAYHYLCHHGECENEI 134
Query: 79 IEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQ 126
+ ++GN G VA A G CTI P+ + K+ + GAE+V+
Sbjct: 135 VCASTGNMGASVAAYCARGGIRCTIYVPNDTAKIKLLQMMAHGAEIVR 182
>UniRef50_Q9PH18 Cluster: Cysteine synthase; n=8; Bacteria|Rep:
Cysteine synthase - Xylella fastidiosa
Length = 390
Score = 54.8 bits (126), Expect = 4e-06
Identities = 70/307 (22%), Positives = 115/307 (37%), Gaps = 21/307 (6%)
Query: 38 ECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVC 97
+ + + K E ++P GS+K R++ ++ L A +G G IE +SG+T + A +
Sbjct: 58 DIDFYLKDESIHPTGSLKHRLARSLFLYALVNGWLSPGRPVIEASSGSTAVSEAYFARLL 117
Query: 98 GFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAI--- 154
G V P S EK++ I G + H L+ D
Sbjct: 118 GLPFIAVIPTSTSPEKVAAIEFHGGRCHAVERACDLHDAAHQLARETGGHFMDQFTYAER 177
Query: 155 SCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVT 214
+ D N+ + ++ A+E P I + V+ + I+
Sbjct: 178 ATDWRANNNIAESIFKQMADE---PHPIPSWIVCSPGTGGTAATLGRYVRYRRHVTRILC 234
Query: 215 VDPQGSLIFG------EGPADLYFVEGIGGDFVPDV----LDKS----VIDKVEKPNDYD 260
DP+ S+ F +G V GG V + L+ S ID + K D
Sbjct: 235 ADPEISVFFDHYRAACKGSDHRNNVTDTGGSRVEGIGRPRLEPSFIHDCIDAMIKVPDAL 294
Query: 261 AFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNF-GAGKRVVVILPDGIRNYMTKFVC 319
+ R I + G GGS+G M+ ++ A ++ G +V IL DG Y +
Sbjct: 295 SLAAMRYISARLGRRVGGSTGTNMVGVLQTAARMRAEGMKGSIVTILCDGGERYAHSYYS 354
Query: 320 DQWMEAH 326
W AH
Sbjct: 355 PAWYAAH 361
>UniRef50_Q3EKD4 Cluster: Cysteine synthase; n=2; Bacillus cereus
group|Rep: Cysteine synthase - Bacillus thuringiensis
serovar israelensis ATCC 35646
Length = 277
Score = 54.4 bits (125), Expect = 6e-06
Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 10/160 (6%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
+G+TPL++L + ++AKCE+ NP GSIKDR + M+ + + K +
Sbjct: 13 VGNTPLMKLEC---EETKNLSIYAKCEWHNPTGSIKDRAALGMINKYLQEADKKQ--NIL 67
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWES-SEH 138
E + G+ + G CT+V ++ + GA V+ + + E
Sbjct: 68 EYSGGSLARSIGCICNCLGIECTLVLSSATGQSLLNKLKYYGANVILVDKCKGFYAVIEK 127
Query: 139 FLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILA 178
+ ++K ++P Q+ N+ N +H E T EI+A
Sbjct: 128 AIEISK----QNPELYFLFQHYNNANIVSHIEGTGREIIA 163
>UniRef50_Q54ZW3 Cluster: Threonine ammonia-lyase; n=2;
Dictyostelium discoideum|Rep: Threonine ammonia-lyase -
Dictyostelium discoideum AX4
Length = 1173
Score = 54.0 bits (124), Expect = 7e-06
Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 12/177 (6%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
+N I + P+ K G C++ E GS K R S MVL A + +
Sbjct: 721 HNRIKHIMTQPPIYHSTTYSKICG--CKVTLMLENTQKTGSFKIRGSSNMVLRALEGAMV 778
Query: 73 KSGTR---FIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
+ R + ++GN GVAL +A G CTIV P+ D K+S+ GAEV++
Sbjct: 779 NTDERPVGLVAASAGNHAQGVALISAKVGLPCTIVCPEYAPDSKLSSTRQYGAEVIK--- 835
Query: 130 MAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMI 186
+S E + +A + ++ N Y NDV+ +I VPDVD +
Sbjct: 836 --KGKSLEEAVKLAD-EICKERNWTLVRPY-NDVDVIEGQGTMGCDIYDKVPDVDTV 888
>UniRef50_A2R2J5 Cluster: Catalytic activity:
O3-acetyl-L-serine+H(2)S<=>L-cysteine+acetate; n=6;
Pezizomycotina|Rep: Catalytic activity:
O3-acetyl-L-serine+H(2)S<=>L-cysteine+acetate -
Aspergillus niger
Length = 530
Score = 54.0 bits (124), Expect = 7e-06
Identities = 53/248 (21%), Positives = 107/248 (43%), Gaps = 15/248 (6%)
Query: 67 QKSGIAKSGTRFIEPTSGNTGIGVA-LATAVCGFGCT-IVTPDKNSDEKMSTISLLGAEV 124
+K+ + +E +SG+T I ++ LA + G T +K+++ K+ + G +V
Sbjct: 62 EKTVVPGKTQTIVEFSSGSTVISMSMLARLMHGISDTRAFLSNKSTETKLRMMQFFGLDV 121
Query: 125 VQT--PAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPD 182
P+ + A+ ++ ++ +QY ND N H +T +I +P+
Sbjct: 122 TLFGGPSQPDPFDERGGIQTARAMAMQSDEIVNPNQYDNDDNWHAHIRWTGPQIFKQLPE 181
Query: 183 VDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTV-DPQGSLIFGEGPADLYFVEGIGGDFV 241
++++ KE P + + V G + GP ++ V
Sbjct: 182 INVLCAGMGTSGTMTGLGTYFKEVKPSVLRLGVCTAPGDRV--PGPRTFALMQ------V 233
Query: 242 PDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKR 301
+ + +D E+ + YDAF++S ++ +EG++CG SSG ++ + +K AG
Sbjct: 234 QEFPWREALDVHEEVSSYDAFSLSLDLC-REGVVCGPSSGLSLKGLYQMLEKRK-SAGTL 291
Query: 302 VVVILPDG 309
+ PDG
Sbjct: 292 QQLAGPDG 299
>UniRef50_Q9K7E3 Cluster: Threonine synthase; n=51; cellular
organisms|Rep: Threonine synthase - Bacillus halodurans
Length = 354
Score = 54.0 bits (124), Expect = 7e-06
Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 7/107 (6%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G+TPL+ L + K++G++ + K E NP GS KDR V +A++ G I
Sbjct: 29 GNTPLIPLENLSKEWGVKA--YVKYEGANPTGSFKDRGMVMAVAKAKEEG----SRTIIC 82
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPD-KNSDEKMSTISLLGAEVVQ 126
++GNT A A G C +V P+ K + K++ + GAEV++
Sbjct: 83 ASTGNTSAAAAAYGARAGLRCIVVIPEGKIALGKLAQAVMYGAEVLE 129
>UniRef50_Q4PAX1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 560
Score = 53.2 bits (122), Expect = 1e-05
Identities = 47/208 (22%), Positives = 90/208 (43%), Gaps = 12/208 (5%)
Query: 80 EPTSGNTGIGVALATAVCGFGCTIV-TPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEH 138
E +SG+T +A+ G +K S K S + G E+ + +
Sbjct: 96 ESSSGSTVTSMAMIARQHGVSKVRAWMSNKVSPTKSSLMRFFGLELALFGGPSQSPPRDP 155
Query: 139 FLSVAKRRLL-EDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXX 197
+AK P + +QY+N NP H +T +++L +PD+++
Sbjct: 156 MGGIAKAAAQGSQPGVFNPNQYENPANPAAHERWTGKQLLQQLPDINVFAGGMGTGGTIT 215
Query: 198 XXAQKVKEKCPKCIIVTV-DPQGSLIFGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKP 256
A ++K+ P ++ V +G I G P +L +E + D K ++D VE
Sbjct: 216 GTATRLKQDRPDMHVIGVCVARGHKIPGPRPREL--LEPV------DFAWKPLVDSVEDV 267
Query: 257 NDYDAFNMSREIIKKEGLLCGGSSGAAM 284
+++ +S ++ + G++CG SSG ++
Sbjct: 268 ASRESYTLSMQLC-RYGIVCGPSSGFSL 294
>UniRef50_A6RLV9 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 348
Score = 53.2 bits (122), Expect = 1e-05
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
TPLVR + + G C ++ K E + P GS K R +++ + + F +
Sbjct: 23 TPLVRSAALSRHAG--CNVWLKLENLQPSGSFKSRGIGNLLIRSLPPN-PHTPVHFYCSS 79
Query: 83 SGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSV 142
GN G+ A A CTIV P S +S I LL AEVVQT W ++ +L
Sbjct: 80 GGNAGLACAHAAFSLKRPCTIVVPMTTSSHMISKIKLLKAEVVQTG--NHWSEADRYL-- 135
Query: 143 AKRRLLEDPNAI 154
+ L D N +
Sbjct: 136 REELLANDANGV 147
>UniRef50_Q2CJ64 Cluster: Threonine synthase; n=1; Oceanicola
granulosus HTCC2516|Rep: Threonine synthase - Oceanicola
granulosus HTCC2516
Length = 367
Score = 52.8 bits (121), Expect = 2e-05
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPLV+ RI + G+ F K E +NP GS KDR + V A+ G A +
Sbjct: 26 GGTPLVKSRRIGAEAGIPDLRF-KLEQLNPTGSYKDRFAGLAVGLARAEGHAAC----VA 80
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
+SGNTG +A A G GC + + K+ + GA+V
Sbjct: 81 TSSGNTGAALAAFCARAGMGCALYVSENAPQGKLEQMLAYGADV 124
>UniRef50_A1HTF2 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Thermosinus carboxydivorans Nor1|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Thermosinus carboxydivorans Nor1
Length = 329
Score = 52.8 bits (121), Expect = 2e-05
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 4/89 (4%)
Query: 40 EMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGF 99
E+ K ++ P GS KDR ++ ++ + +GI T +E +SGN G +A A G
Sbjct: 59 EVNLKLDYFMPTGSFKDRGAFILINAIKAAGI----TEVVEDSSGNAGASIAGYCAAAGI 114
Query: 100 GCTIVTPDKNSDEKMSTISLLGAEVVQTP 128
C I P+ S K+ +S A VV+ P
Sbjct: 115 KCNIYIPESTSPGKIKQLSAYQANVVKVP 143
>UniRef50_Q0SFD0 Cluster: Probable threonine ammonia-lyase; n=1;
Rhodococcus sp. RHA1|Rep: Probable threonine
ammonia-lyase - Rhodococcus sp. (strain RHA1)
Length = 314
Score = 52.4 bits (120), Expect = 2e-05
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 10 NRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKS 69
+R I I TP R +P +G +F K EF+ GGS K R S +L A++
Sbjct: 11 DRARERITGLIRRTPTFRAT-VPTVHGAVPVIF-KLEFLQYGGSFKVRGSLNALLHAEED 68
Query: 70 GIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
G I + GN IG A A+ + G CT+V P D K+ + LGA+V
Sbjct: 69 GRLDDAGVVIA-SGGNAAIGAAWASRLRGVKCTVVVPVTAPDVKIDKLIALGADV 122
>UniRef50_A4JPB4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Burkholderia vietnamiensis G4|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Burkholderia vietnamiensis (strain G4 / LMG 22486)
(Burkholderiacepacia (strain R1808))
Length = 334
Score = 52.0 bits (119), Expect = 3e-05
Identities = 63/279 (22%), Positives = 110/279 (39%), Gaps = 11/279 (3%)
Query: 59 SYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTIS 118
++ ++ +A+ G + G +E +SGN +G+A+ + +
Sbjct: 36 AHYIISKARDRGDLQPGKTVVETSSGNFALGMAIVCNRLNHPFVAIGDPAIDPAFKRQLE 95
Query: 119 LLGAEV-VQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEIL 177
+LG V + T + L + L + A C QY N+ N Y A E+L
Sbjct: 96 MLGGRVEIVTDKKGSQGYQKARLDRLQEILAAEQGAFWCRQYDNE-NNGLAYANIARELL 154
Query: 178 ALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG--EGPADLYFVEG 235
+V ++ A ++ C +V VD S++FG +GP L G
Sbjct: 155 EIVGPRLILVAPVGSGGSSCGIAAALRAGGADCTLVGVDTFNSVLFGQIDGPRKL---RG 211
Query: 236 IGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLN 295
+G +P L + D V + A + +R++ K G G ++GAA + +R + N
Sbjct: 212 LGNTIMPGNLKHMLFDDVHWVSSELADHFTRKLYKTTGHFRGPTTGAA-FAVVRFVR--N 268
Query: 296 FGAGKRVVVILP-DGIRNYMTKFVCDQWMEAHLFKEPPE 333
+V + P DG R T F + A+ P E
Sbjct: 269 RYPDAPIVFLSPDDGSRYVDTTFASNDDSPAYDQLRPVE 307
>UniRef50_Q9EX46 Cluster: Putative cysteine synthase; n=4;
Streptomyces|Rep: Putative cysteine synthase -
Streptomyces coelicolor
Length = 340
Score = 51.6 bits (118), Expect = 4e-05
Identities = 54/245 (22%), Positives = 98/245 (40%), Gaps = 5/245 (2%)
Query: 53 SIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDE 112
S+K + V + G + G I+ +SG +ALA G C +V
Sbjct: 29 SMKIYSALAAVRHLLERGTIRPGQTLIDSSSGIYAYALALACHRYGMRCHVVASTTVDTT 88
Query: 113 KMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLED-PNAISCDQYKNDVNPRTHYEY 171
+ + +LGA V Q + + R +L D P+ QY +DV+ Y+
Sbjct: 89 TRAQLEILGATVEQVRPSRNLKLDQELRVRRVREILADHPDWHWMRQYHDDVH-YLGYQE 147
Query: 172 TAEEILALVPDVDM-IXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFG-EGPAD 229
A+ I P + + ++++ P +V V P GS+ FG + D
Sbjct: 148 VADRITTAFPSTPLTVVGGVGSGASTGGLVERLRATDPSVRLVGVQPFGSVTFGSQAHHD 207
Query: 230 -LYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAI 288
+ GIG V D + + D V + A + + ++++ + G S+GA ++A
Sbjct: 208 PEAIIAGIGSSIVFDNVRHHLYDAVHWLDFTHAMSGTIALLRERAVFAGLSTGAGYLAAT 267
Query: 289 RAAKK 293
A++
Sbjct: 268 YEARR 272
>UniRef50_Q024T6 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Solibacter usitatus Ellin6076|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Solibacter usitatus (strain Ellin6076)
Length = 305
Score = 50.0 bits (114), Expect = 1e-04
Identities = 68/307 (22%), Positives = 112/307 (36%), Gaps = 37/307 (12%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
Y I T+ +TPL R CE + K E + GS K R + A K G+
Sbjct: 9 YERIRGTVRETPLER--------AAGCEAWLKLEHLQHTGSFKFRGA------ANKIGLL 54
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP 132
+ ++GN G+GVA A G + S K + I GA +
Sbjct: 55 AGAQEVVTASNGNHGLGVAAAAEARGIAAEVFVSSHVSRAKAARIQARGARICYA----- 109
Query: 133 WESSEHFLSVAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXX 192
+A RR E+ + Y ND++ A E+L PD+D +
Sbjct: 110 -GDDPLTAEMAARRAAEETGRVYISPY-NDLDVAAGQGTIAVELLRQAPDLDAVFVAVGG 167
Query: 193 XXXXXXXAQKVKEKCPKCIIVTVDPQGSLIF------------GEGPA-DLYFVEGIGGD 239
+K P+ +V P+ S + E P G+
Sbjct: 168 GGLIGGIGSYLKAMSPRTEVVGCWPENSPVMKACLEAGKIVEVAERPTLSESTAGGLEEG 227
Query: 240 FVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAG 299
V L + ID+ + + R +++ E L G++G AM + ++ AK+ + G
Sbjct: 228 SVTFELCRQSIDRSVLVTEEEILGAMRFVLQTEHWLIEGAAGVAMAAYLKDAKRYH---G 284
Query: 300 KRVVVIL 306
++ V+L
Sbjct: 285 RKAAVVL 291
>UniRef50_A4FDP6 Cluster: Cysteine synthase A; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Cysteine
synthase A - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 291
Score = 50.0 bits (114), Expect = 1e-04
Identities = 63/278 (22%), Positives = 107/278 (38%), Gaps = 20/278 (7%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
+ AK E+ NP GSIKDR ++ ++ E G +E + GN +++ G
Sbjct: 12 VLAKAEWENPCGSIKDRTAFALLCEVLADCDDPRGLHLVEYSGGNLAAPLSVLCGRLGVR 71
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYK 160
T+V + + + + GA V + E FL V +R Q++
Sbjct: 72 LTLVLSEATPGDYVDELRSRGAAVDLV------DREEGFLGVMERARELSGTGRLLYQHR 125
Query: 161 NDVNPRTHYEYTAEEILALVPDV--DMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQ 218
+ N H T E++ + + D + E+ P V V P
Sbjct: 126 SQANLWMHRISTGAEVVEQLGEAVPDRFVASVGTGGTLVGVLSALGERHPGVRGVVVTP- 184
Query: 219 GSLIFG--EGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDY------DAFNMSREIIK 270
L +G E P G GG + V+ V++ + Y A ++ R+ +
Sbjct: 185 SELPYGSDEPPNGRPKYAGSGG-LGNGIRQPFVLGAVDRMDGYRTVSRPRAISLMRQCLD 243
Query: 271 KEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPD 308
+ G+ G S+ A +A+ A +L G G VV + PD
Sbjct: 244 ETGMRLGSSAAANWRTALDVAAEL--GEGATVVTVFPD 279
>UniRef50_Q9UZV8 Cluster: ThrC threonine synthase; n=5; Archaea|Rep:
ThrC threonine synthase - Pyrococcus abyssi
Length = 394
Score = 50.0 bits (114), Expect = 1e-04
Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPL RLN + K G++ E++AK E NP GS KDR V +A + G+ R
Sbjct: 66 GGTPLYRLNNLEKILGVK-ELYAKNEGANPTGSFKDRGMTVGVSKALELGM----KRVAC 120
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPD-KNSDEKMSTISLLGAEVV 125
++GNT +A A G ++ P K + K++ + GA+V+
Sbjct: 121 ASTGNTSASLAAYAAKAGIEAYVLVPSGKIALGKLAQAIIYGAKVI 166
>UniRef50_Q89XS1 Cluster: Cysteine synthase/cystathionine
beta-synthase family protein; n=134; Bacteria|Rep:
Cysteine synthase/cystathionine beta-synthase family
protein - Bradyrhizobium japonicum
Length = 387
Score = 49.6 bits (113), Expect = 2e-04
Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Query: 22 DTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEP 81
DT L+RL +P G++ ++ K E +P GS+K R++ ++ L A +G + GT +E
Sbjct: 39 DTHLIRLI-VPALSGID--IYLKDESTHPTGSLKHRLARSLFLYALCNGHIREGTPVVEA 95
Query: 82 TSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG 121
+SG+T + A + G V P S EK++ I G
Sbjct: 96 SSGSTAVSEAYFAQMIGVPFYAVMPRTTSAEKIAAIEHYG 135
>UniRef50_Q97ZT5 Cluster: Threonine synthase; n=6; Archaea|Rep:
Threonine synthase - Sulfolobus solfataricus
Length = 345
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 44 KCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI-EPTSGNTGIGVALATAVCGFGCT 102
K +F+NP GS KDR + T+V S +A+ G + I E +SGN G +A +A G
Sbjct: 80 KLDFLNPSGSYKDRGAVTLV-----SYLAEKGVKQISEDSSGNAGSAIAAYSAAAGIEAY 134
Query: 103 IVTPDKNSDEKMSTISLLGAEVVQ 126
I P+ K+ I GA VV+
Sbjct: 135 IFVPETAKGGKLKQIESYGAHVVR 158
>UniRef50_A3H5T4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Caldivirga maquilingensis IC-167|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Caldivirga maquilingensis IC-167
Length = 357
Score = 49.6 bits (113), Expect = 2e-04
Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 40 EMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGF 99
+ + K E++NP GS KDR +++ L ++ + +E +SGN G+ +A +AV G
Sbjct: 80 DYYFKLEYLNPTGSFKDR-GWSLALSVLRNDVT-----VVEDSSGNAGLSLAAYSAVKGV 133
Query: 100 GCTIVTPDKNSDEKMSTISLLGAEVVQTPAMA 131
I P + K + LLGA VV+ A
Sbjct: 134 RARIYVPKTAPEAKKRLMRLLGANVVEAATRA 165
>UniRef50_A3DMX4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Staphylothermus marinus F1|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 /
F1)
Length = 355
Score = 49.6 bits (113), Expect = 2e-04
Identities = 37/106 (34%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPLV D ++ K E++NP GS KDR + + G KS +E
Sbjct: 67 GGTPLV------VDEENNAKLLFKLEYLNPSGSFKDRGTALAIGYGYLLGY-KS---VVE 116
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQ 126
TSGNTGI V L + V G I+ P K + LLG E+++
Sbjct: 117 DTSGNTGISVTLYSRVYGLKPLIIMPKNAPLGKKKLVKLLGGEIIE 162
>UniRef50_Q7NS30 Cluster: Probable cysteine synthase B; n=1;
Chromobacterium violaceum|Rep: Probable cysteine
synthase B - Chromobacterium violaceum
Length = 273
Score = 49.2 bits (112), Expect = 2e-04
Identities = 56/251 (22%), Positives = 100/251 (39%), Gaps = 14/251 (5%)
Query: 44 KCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTI 103
K E++NP SIK R +L ++G GT T+G+ G+ VA A + G +
Sbjct: 17 KLEYLNPSLSIKHRSLPKTLLARAEAGRIGRGTTLAIMTAGSAGVSVAWAASQIGCKALL 76
Query: 104 VTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDV 163
+ P+ D ++ LGA V + P E + R + D + + + +D
Sbjct: 77 LMPESAPDSVVNYARWLGAAVERRPHPQLQELLD------AHRGMPDSHVV---EQLSDA 127
Query: 164 NPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCI-IVTVDPQGSLI 222
HY EE+L P + + A+ + P I + +P + +
Sbjct: 128 ELIGHYRAVGEELLRQSPGLAAVTVPAGTCASLMGIAEAL---APAGIPVYAAEPAEAAV 184
Query: 223 FGEGPADLYFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGA 282
P + + G+ + + + + A++ +RE + G G SSGA
Sbjct: 185 LSGEPWRPHDIPGLAPPAPTKLFRREAVAGIVPVASALAWSTAREALAACGEPVGPSSGA 244
Query: 283 AMISAIRAAKK 293
A I+A RA ++
Sbjct: 245 A-IAAARALRR 254
>UniRef50_Q2IRQ4 Cluster: Threonine synthase; n=1; Rhodopseudomonas
palustris HaA2|Rep: Threonine synthase -
Rhodopseudomonas palustris (strain HaA2)
Length = 420
Score = 49.2 bits (112), Expect = 2e-04
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G +PL +L + GL+ ++ K E NP S KDR++ V A++ G AK+ +
Sbjct: 80 GGSPLRQLRAVGDQLGLK-RLYGKDESGNPTWSFKDRLACIAVSVAKQMG-AKT---IVS 134
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAP-WESSEH 138
+SGN G A A G C + T + ++ + GA+VV P W EH
Sbjct: 135 SSSGNAGAAAAAYAAKAGIPCVVFTFGWAAGPMVTQMRAYGAKVVTVPQKEDRWRFMEH 193
>UniRef50_Q6C6D8 Cluster: Yarrowia lipolytica chromosome E of strain
CLIB 122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome E of
strain CLIB 122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 329
Score = 48.8 bits (111), Expect = 3e-04
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 22 DTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKS--GTRFI 79
+TPL++ + G C ++ K E + P GS K R ++ +A S S
Sbjct: 7 ETPLLKNDIFSHQVG--CNVYLKMENLQPSGSFKSRGMTQVISDALDSDPQASLDTLHVC 64
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHF 139
+ GN G+ A+ + + G CT+V P+ + + GAEV+ W + F
Sbjct: 65 SSSGGNAGLAAAVTSRLNGVACTVVVPESTKPRMVEKLRAAGAEVIVHG--KHWSEANDF 122
Query: 140 LSVAKRRLLE 149
L + LE
Sbjct: 123 LQKEEMPRLE 132
>UniRef50_Q1DVD5 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 426
Score = 48.8 bits (111), Expect = 3e-04
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 22 DTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR--FI 79
+TPL+ + + G C +F K E + P GS K R +VL + S A G + F
Sbjct: 18 ETPLIESPSMSRMAG--CRIFLKLENLQPSGSFKSRAIGNLVL-SYASDPANQGKQLHFF 74
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQ 126
++GN G+ A A + + CT+ P ++ + GA V Q
Sbjct: 75 ISSAGNAGLAAATAASALSYPCTVCVPTSTKPVMVNKLQEAGATVAQ 121
>UniRef50_A3DKY8 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Staphylothermus marinus F1|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 /
F1)
Length = 436
Score = 48.8 bits (111), Expect = 3e-04
Identities = 64/286 (22%), Positives = 118/286 (41%), Gaps = 33/286 (11%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPL+R + + ++ + + K E NP GS +DR + +V +A G AK R +
Sbjct: 65 GWTPLIRSDNLFRNENI----YFKDESRNPTGSFRDRAAALIVSDALDQG-AK---RLVV 116
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFL 140
+ GN G +A +A G TI P EK+ + GA+V+ + E + L
Sbjct: 117 ASDGNMGASIAAYSAKAGLPVTIYVPVWTDPEKILLMKAYGAKVIVSE-----EDLDTLL 171
Query: 141 SVAKRRLLEDP--------NAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXX 192
+RR ++ N ++ + K + + +Y VP +
Sbjct: 172 QYVERRARKEKLYNASSTYNILAMEGLKT-IGYEIYLQYGGVPSTVYVPLGSGLTILSLY 230
Query: 193 XXXXXXXAQKVKEKCPKCIIV--TVDPQGSLIFG-------EGPADLYFVEGIGGDFVPD 243
+ + + PK I V +P S I G E LY+ + + ++V +
Sbjct: 231 HGFSEMHSNNIIDHIPKLIGVETCANPVYSSIHGNPTKCNEEPMPGLYYRKPVLKEYVSE 290
Query: 244 VLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIR 289
++DK + N+ + ++++ +EGL SS A+ A++
Sbjct: 291 IIDKH--GETIVVNNKQVYMAAKKLAMEEGLFVEPSSAVALAGALK 334
>UniRef50_Q67LA4 Cluster: Threonine synthase; n=1; Symbiobacterium
thermophilum|Rep: Threonine synthase - Symbiobacterium
thermophilum
Length = 399
Score = 48.4 bits (110), Expect = 4e-04
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 7/107 (6%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G+TPLV R+ + GL+ ++ K E +NP GS KDR + +A ++G AK+ I
Sbjct: 29 GNTPLVPAPRLGAELGLD--LYLKFEGLNPTGSFKDRGMTLAMSKAVEAG-AKA---VIC 82
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPD-KNSDEKMSTISLLGAEVVQ 126
++GNT A A G C +V PD + K++ + GA +Q
Sbjct: 83 ASTGNTSASAAAYAARAGLPCYVVIPDGAVAMGKLAQALMYGARTIQ 129
>UniRef50_A6C9B2 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Planctomyces maris DSM 8797|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Planctomyces maris DSM 8797
Length = 326
Score = 48.4 bits (110), Expect = 4e-04
Identities = 74/310 (23%), Positives = 129/310 (41%), Gaps = 43/310 (13%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDR----ISYTMVLEAQKSGIAKSGTRF 78
TPL+ + + G + +F K E P G+ K R + T+ E +++GI T
Sbjct: 23 TPLIEWPGLSRLTGTQ--LFLKHENHQPVGAFKVRGGINLVSTLSEEERQAGIMGCST-- 78
Query: 79 IEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEH 138
GN G +A A G CTIV P N+ +K+ I +LGAE++ E+ E
Sbjct: 79 -----GNHGQSLAFAARKYGVKCTIVVPRNNNPDKVEAIRMLGAEII--------EAGED 125
Query: 139 FLSVAKRRLLEDPNAISCDQYKNDVN-PRTHYEYTAE--EILALVPDVDMIXXXXXXXXX 195
F ++ LE+ +Y + N P+ + EI +P+ D+I
Sbjct: 126 FNEA--KQYLEEQLIDGKRRYVHSANEPKLIAGVGTQGIEIFDTLPNPDVILVPVGMGSG 183
Query: 196 XXXXAQKVKEKCPKCIIVTVD----PQGSLIFGEG-----PADLYFVEGI----GGDFVP 242
+ P+ ++ V P L + G P + EG+ G +F
Sbjct: 184 VCGTGIVARYMRPQTEVIGVQAENAPANQLSWKAGTAITTPTASTWAEGVATRAGAEFTQ 243
Query: 243 DVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRV 302
++ +SV+D ++ + + I+K+ L G+ AA+ + ++ + AGK+V
Sbjct: 244 QIM-QSVLDDFLLVSEEEMRIAAYHILKQTHNLAEGAGAAALAAVLKNPARF---AGKKV 299
Query: 303 VVILPDGIRN 312
V +L G N
Sbjct: 300 VAVLSGGNLN 309
>UniRef50_A0GA25 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Burkholderia phymatum STM815|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Burkholderia phymatum STM815
Length = 305
Score = 48.4 bits (110), Expect = 4e-04
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
++AK EF NP GS KDR+S + AQ++ ++ T + +SGN G+ +A A G
Sbjct: 2 LYAKNEFANPTGSHKDRMS---AIVAQRALDIRAKTIAVA-SSGNAGVSMAAYAARAGID 57
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVV 125
C +VT S I + GA ++
Sbjct: 58 CVVVTTPDMSQNWRRAIEMHGARII 82
>UniRef50_P74193 Cluster: Threonine synthase; n=123; Bacteria|Rep:
Threonine synthase - Synechocystis sp. (strain PCC 6803)
Length = 382
Score = 48.4 bits (110), Expect = 4e-04
Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G+TPL+ I K G + +F K + +NP GS KDR TM + K AK+ I
Sbjct: 59 GNTPLIPAPAIAKRIGKDVRVFVKYDGLNPTGSFKDR-GMTMAISKAKEAGAKA---VIC 114
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKN-SDEKMSTISLLGAEVV 125
++GNT A G ++ PD + K+ + GAEV+
Sbjct: 115 ASTGNTSAAAAAYARRAGLRAFVIIPDGYVALGKLGQALIYGAEVI 160
>UniRef50_Q12EY4 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=3; Comamonadaceae|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 313
Score = 48.0 bits (109), Expect = 5e-04
Identities = 38/111 (34%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 20 IGDTPLVRLNRIPKDYGLEC-EMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRF 78
I TPL +L K G+ C E++ K E + GGS K R +L + I SG
Sbjct: 22 IRQTPLWKLPG--KALGVACAEVWLKLEHLQTGGSFKARGMLNRLLS---NPIPPSGV-- 74
Query: 79 IEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA 129
I + GN GI A A G C + P+ +S K + ++ LG+ VV T A
Sbjct: 75 IVASGGNAGIATAAAAKELGVHCEVFVPEVSSPAKRARLAALGSRVVVTGA 125
>UniRef50_Q9Y9K2 Cluster: Threonine synthase; n=1; Aeropyrum
pernix|Rep: Threonine synthase - Aeropyrum pernix
Length = 393
Score = 48.0 bits (109), Expect = 5e-04
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 7/107 (6%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPLV+L + + G+E ++ K EF+NP GS KDR T+ + S S +
Sbjct: 57 GSTPLVKLENLSRAMGVE--VYGKLEFLNPTGSFKDR-GMTVGVSIASS---FSYRLVVA 110
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKN-SDEKMSTISLLGAEVVQ 126
++GNT +A G I+ P + K+S I+ LGA V++
Sbjct: 111 ASTGNTAASMAAYARRAGLNPVILIPKGGIASGKLSQIAALGAWVLE 157
>UniRef50_UPI00015BAF2C Cluster: L-threonine synthase; n=1;
Ignicoccus hospitalis KIN4/I|Rep: L-threonine synthase -
Ignicoccus hospitalis KIN4/I
Length = 408
Score = 47.6 bits (108), Expect = 6e-04
Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 6/107 (5%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G+TPL+RL ++ K G+ ++AK E NP GS KDR ++ + K A++ +
Sbjct: 74 GNTPLIRLEKLEKVIGVR-RLYAKFEGANPTGSFKDR-GMSLAVTVAKEVKARA---VVA 128
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPD-KNSDEKMSTISLLGAEVVQ 126
++GNT A +A G ++ P K + K++ L GA VV+
Sbjct: 129 ASTGNTAASAAAYSARAGLKTFLILPSGKVALGKLAQSLLHGAVVVE 175
>UniRef50_Q5KZ40 Cluster: Threonine synthase; n=7; Bacteria|Rep:
Threonine synthase - Geobacillus kaustophilus
Length = 405
Score = 47.6 bits (108), Expect = 6e-04
Identities = 31/104 (29%), Positives = 54/104 (51%), Gaps = 5/104 (4%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPLV + R+ ++ G+E ++ K E V P G+ K R + + +A++ G+ +
Sbjct: 79 GMTPLVPMPRLGREIGIEA-LYMKDEGVIPTGTFKARGAAVGISKAKELGVKQLAM---- 133
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
PT+GN G +L A G T+V P + + ++ GAE+
Sbjct: 134 PTNGNAGAAWSLYAARAGIQATVVMPVEAPELTRKECAIAGAEL 177
>UniRef50_A6G3T5 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Plesiocystis pacifica SIR-1|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Plesiocystis pacifica SIR-1
Length = 349
Score = 47.6 bits (108), Expect = 6e-04
Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
TPLVR + G++C K E P G+ K R ++L + A+ ++ T
Sbjct: 46 TPLVRHPGLSARVGVDC--LVKLENTQPVGAFKVRGGLNLLLTSSPEQRARG---YVTAT 100
Query: 83 SGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPA--MAPWESS 136
GN G +A A A G C +V P N K + LGAE++ T A WE++
Sbjct: 101 RGNHGQSLAYACARFGSRCALVVPRGNDPAKNRAMRELGAELLVTGVDFDAAWEAA 156
>UniRef50_Q965I8 Cluster: Putative uncharacterized protein T25D3.3;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T25D3.3 - Caenorhabditis elegans
Length = 427
Score = 47.6 bits (108), Expect = 6e-04
Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Query: 1 MSNSRSFTRNRIYNNILET--IGDTPLVRLNRIPKDYGL-ECEMFAKCEFVNPGGSIKDR 57
M+ S+ +TR+ I E +G TP+ + GL + K E + GS+K R
Sbjct: 41 MTESKEWTRDAIQKMWSERNLMGSTPI----HVIDPPGLPSVRLVFKNESASLTGSLKHR 96
Query: 58 ISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTI 117
S+++++ A G K+GT E +SGNT + + G T V PD K+ I
Sbjct: 97 YSWSLMMWALLEGHVKNGTHVFEASSGNTACSLGYMCRLLGLQFTAVVPDTIEQVKVRRI 156
Query: 118 SLLGAEVVQTP 128
VV+ P
Sbjct: 157 EEQEGFVVRVP 167
>UniRef50_A4R1F1 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 344
Score = 47.6 bits (108), Expect = 6e-04
Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 7/133 (5%)
Query: 22 DTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEP 81
+TP + ++ + G C ++ K + + P GS K R M+ A + F P
Sbjct: 14 ETPCLYSPQVSRAAG--CNIYLKLDNLQPSGSFKSRGIGNMMQRAIAL-TPRDDVHFYCP 70
Query: 82 TSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLS 141
+ GN G+ A + A G TIV P K + + LGAEV++ E+ + S
Sbjct: 71 SGGNAGLACATSAASLGKPATIVVPIKTPAHMVEKLEALGAEVLRRGGSIA-EADAYLKS 129
Query: 142 VAKRRLLEDPNAI 154
+ L+ DPN +
Sbjct: 130 ---QLLINDPNGV 139
>UniRef50_Q4LEC5 Cluster: Threonine synthase; n=1; uncultured
crenarchaeote 10-H-08|Rep: Threonine synthase -
uncultured crenarchaeote 10-H-08
Length = 414
Score = 47.6 bits (108), Expect = 6e-04
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 7/107 (6%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTR-FI 79
G+TPL+ R+ + G++ +F K E NP S KDR M + A K+ + G R +
Sbjct: 78 GNTPLLHAQRLGGELGVK-RLFLKDETRNPTASFKDR---AMAVGAAKA--VEMGRRDVV 131
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQ 126
+SGN +A +A G CT P+ + K S + L GA V++
Sbjct: 132 IASSGNAASSLAAYSASLGLRCTAFVPEDVAMGKASQLLLYGARVLR 178
>UniRef50_Q5K9Z3 Cluster: L-serine ammonia-lyase, putative; n=2;
Filobasidiella neoformans|Rep: L-serine ammonia-lyase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 425
Score = 47.2 bits (107), Expect = 9e-04
Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 5/131 (3%)
Query: 2 SNSRSFTRNRIYNN--ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRIS 59
SN+ + +YN+ I + +TPLV+ + + G C +F K + + P GS K R
Sbjct: 25 SNTMTIATPELYNHKAIPQPWRETPLVQSAALSRLAG--CRIFLKLDNLQPSGSFKSRGI 82
Query: 60 YTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISL 119
+V + + + F + GN G+ A + G+ T+V P + +S +
Sbjct: 83 GNLVRRSIQRSPPNAPLHFYSSSGGNAGLACVTAASSLGYPSTVVVPMTTTPMMISKLFT 142
Query: 120 LGA-EVVQTPA 129
GA +V+Q A
Sbjct: 143 AGASKVIQEGA 153
>UniRef50_A3LQ20 Cluster: Predicted protein; n=5;
Saccharomycetales|Rep: Predicted protein - Pichia
stipitis (Yeast)
Length = 336
Score = 47.2 bits (107), Expect = 9e-04
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 39 CEMFAKCEFVNPGGSIKDR-ISYTMVLEAQKSGIAKS-GTRFIEPTSGNTGIGVALATAV 96
C + KCE+ P GS K R + Y + L K+ K G + GN G+ A A+
Sbjct: 22 CRIVLKCEYEQPSGSFKLRGMGYLVALSIDKARKEKKEGIHVFSSSGGNAGLAAAYASKY 81
Query: 97 CGFGCTIVTPDKNSDEKMSTISLLGAEVV 125
CT+V P + + LGA VV
Sbjct: 82 FNVPCTVVLPVSSKAVVHEKLRSLGANVV 110
>UniRef50_Q8RAI2 Cluster: Threonine synthase; n=14; Bacteria|Rep:
Threonine synthase - Thermoanaerobacter tengcongensis
Length = 462
Score = 46.8 bits (106), Expect = 0.001
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 18/121 (14%)
Query: 20 IGDTPLVRLNRIPK------DYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
+G+TPL+ L + + G +F K E NP GS K+R + V A+K G
Sbjct: 51 VGNTPLIELKNLTELARKVSPTGKAARIFIKDEACNPSGSFKERRASVSVYHAKKHGY-- 108
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSD--------EKMSTISLLGAEVV 125
G I TSGN G VA A+ G C +V +S EK GAEVV
Sbjct: 109 KGV--IAATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEKGRKCETFGAEVV 166
Query: 126 Q 126
Q
Sbjct: 167 Q 167
>UniRef50_Q64CL8 Cluster: Threonine synthase; n=1; uncultured
archaeon GZfos1D1|Rep: Threonine synthase - uncultured
archaeon GZfos1D1
Length = 358
Score = 46.8 bits (106), Expect = 0.001
Identities = 40/139 (28%), Positives = 58/139 (41%), Gaps = 12/139 (8%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPLV L R+ + K E NP GS KDR S + +A G R +
Sbjct: 56 GGTPLVDLTRLMPQAK---KFLVKYEAANPTGSFKDRGSSLEITKAVTWG----RKRAVI 108
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFL 140
++GN G VA A C I+ PD + K+ + GAEV T +
Sbjct: 109 ASTGNMGSSVAAFAAFAKIRCKIIIPDFVNTAKIVQMKAYGAEVELTSG-----DYADAM 163
Query: 141 SVAKRRLLEDPNAISCDQY 159
++A+ ++ DP + Y
Sbjct: 164 NIAENQVRSDPESFLAGDY 182
>UniRef50_A6NQ75 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 454
Score = 46.4 bits (105), Expect = 0.001
Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 5/106 (4%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
+G +PL R +R+ + GL +F K + +NP S+KDR S V++A+++G
Sbjct: 119 VGWSPLYRADRLAQVIGLY-RLFLKDDGLNPTASLKDRASAMAVVKAREAG----ADTIA 173
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVV 125
++GN +A A G I P + K++ + + GA V+
Sbjct: 174 CSSTGNAASSLAGNAAAAGLASYIFVPSRAPRGKVAQLQIFGATVI 219
>UniRef50_A3DKP7 Cluster: Threonine synthase; n=1; Staphylothermus
marinus F1|Rep: Threonine synthase - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 423
Score = 46.4 bits (105), Expect = 0.001
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPL++ NR+ + GL+ ++ K E NP GS KDR V A+ G R +
Sbjct: 78 GGTPLIKANRLAEKLGLK-NLYLKDETRNPTGSFKDRCMSVSVSMAKYFGF----KRAVV 132
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
+SGN +A A G PD K++ + GA+V
Sbjct: 133 ASSGNAAAALAAYGARAGIEVYAFVPDFAGYGKIAQLLFYGAKV 176
>UniRef50_A6VZW2 Cluster: Pyridoxal-5'-phosphate-dependent protein
beta subunit; n=5; Proteobacteria|Rep:
Pyridoxal-5'-phosphate-dependent protein beta subunit -
Marinomonas sp. MWYL1
Length = 320
Score = 46.0 bits (104), Expect = 0.002
Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
I TPL+R +I + L C+++ K E + G+ K R + L K IA I
Sbjct: 21 IKHTPLLRAEKI--ELSLGCQLYLKPENLQITGAFKIRGALNKTLSMSKEEIANG---II 75
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVV 125
+SGN G+A A + G +V P K+ LGAEVV
Sbjct: 76 ATSSGNHAQGLAYAARMLGVKAILVLPVTTPKIKIENTKALGAEVV 121
>UniRef50_A1CH94 Cluster: L-serine dehydratase; n=8;
Trichocomaceae|Rep: L-serine dehydratase - Aspergillus
clavatus
Length = 464
Score = 46.0 bits (104), Expect = 0.002
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 6/108 (5%)
Query: 22 DTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLE--AQKSGIAKSGTRFI 79
+TPLV + + G C +F K E V P GS K R +L + + + F
Sbjct: 19 ETPLVESASLSRAAG--CRIFLKLENVQPSGSFKSRAMGNQILSHLVKPENVGRP-VHFY 75
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGA-EVVQ 126
+ GN G+ A G+ CT+V P ++ + GA +++Q
Sbjct: 76 ASSGGNAGLAAVCAARSLGYPCTVVVPLSTKPLMVNKLRAAGASDIIQ 123
>UniRef50_Q9YBW2 Cluster: Threonine synthase; n=1; Aeropyrum
pernix|Rep: Threonine synthase - Aeropyrum pernix
Length = 340
Score = 46.0 bits (104), Expect = 0.002
Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
Query: 41 MFAKCEFVNPGGSIKDR-ISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGF 99
++AK E++NP GS KDR + Y++ + A G + +SGNTG+ AL +A G
Sbjct: 60 VYAKLEYLNPSGSFKDRGVGYSLRM-ASLLGY----DCVVVDSSGNTGLSTALYSARLGL 114
Query: 100 GCTIVTPDKNSDEKMSTISLLGAEVVQ 126
+ P S K + I GAE+V+
Sbjct: 115 KARVYVPRGASPGKKALIRATGAELVE 141
>UniRef50_UPI00015B8BD6 Cluster: UPI00015B8BD6 related cluster; n=1;
unknown|Rep: UPI00015B8BD6 UniRef100 entry - unknown
Length = 521
Score = 45.6 bits (103), Expect = 0.003
Identities = 69/336 (20%), Positives = 126/336 (37%), Gaps = 20/336 (5%)
Query: 6 SFTRNRI---YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTM 62
SF R+R+ ++I + L R+P +++ K E +P GS+K R++ ++
Sbjct: 141 SFDRSRLRDAVDSIAAEAARSADTHLLRVPLGGSAGIDLYVKDESAHPTGSLKHRLARSL 200
Query: 63 VLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLG- 121
L +G T +E +SG+T + A + G V P + K++ I+ G
Sbjct: 201 FLYGLCNGRIGPRTTIVEASSGSTAVSEAYFAQMLGLPFVAVMPASTAPAKVAEIARYGG 260
Query: 122 -AEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYKNDVN-PRTHYEYTAEEILAL 179
V+ P E+ + + +A ++ + N ++ +E A E
Sbjct: 261 SCHFVEHPGAVYAEAIRIAEETGGLYMDQFTHAERATDWRGNNNIAQSIFEQMARE---R 317
Query: 180 VPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGSLIFGEGPAD---------L 230
P I + ++ + + DP S +F AD
Sbjct: 318 HPVPAWIVVGAGTGGTSATIGRYLRYRGHATRLCLADPDAS-VFHRHLADPSVTARSGTA 376
Query: 231 YFVEGIGGDFVPDVLDKSVIDKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRA 290
VEGIG + S+ID+ D + +R + + G CG S+G + +A
Sbjct: 377 SVVEGIGRARLEPSFLPSLIDRWVAVPDAASLGAARALTEVIGRSCGASTGTNLWAAAEL 436
Query: 291 AKKLNF-GAGKRVVVILPDGIRNYMTKFVCDQWMEA 325
++ G VV +L D Y + W+ A
Sbjct: 437 ISEMAAQGRSGSVVTLLCDSGERYRGTHLDPDWIRA 472
>UniRef50_A7DMC4 Cluster: Threonine dehydratase; n=1; Candidatus
Nitrosopumilus maritimus SCM1|Rep: Threonine dehydratase
- Candidatus Nitrosopumilus maritimus SCM1
Length = 402
Score = 45.6 bits (103), Expect = 0.003
Identities = 47/176 (26%), Positives = 70/176 (39%), Gaps = 10/176 (5%)
Query: 40 EMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGF 99
E++ K EF GS K R +Y + ++ K G + ++GN GVALA+A+
Sbjct: 37 EVYLKAEFRQKTGSFKIRGAYYKI-KSLSDEEKKQGV--VAASAGNHAQGVALASALEEI 93
Query: 100 GCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQY 159
CTIV P S K++ GA VV E + S AK + + +
Sbjct: 94 PCTIVMPKNASPAKVAATKGYGANVV-------LEGVNYDESSAKAKEIAKETGATMIHA 146
Query: 160 KNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTV 215
+D EIL +PDVD + +KEK P ++ V
Sbjct: 147 FDDPQIIAAQGVIGLEILEDLPDVDQVYLPIGGGGLAAGTLIAIKEKNPNVQVIGV 202
>UniRef50_Q8CZG4 Cluster: Threonine dehydratase; n=20;
Proteobacteria|Rep: Threonine dehydratase - Yersinia
pestis
Length = 345
Score = 45.2 bits (102), Expect = 0.003
Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 39 CEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCG 98
CE++ KCE + GS K R + L + G I ++GN G GVALA + G
Sbjct: 61 CEIYLKCEHLQHTGSFKFR-GASNKLRLLNEAQRQQGV--ITASTGNHGQGVALAAKLAG 117
Query: 99 FGCTIVTPDKNSDEKMSTISLLGAEV 124
TI P++ + K+ I LG ++
Sbjct: 118 IKSTIYAPEQAAAIKLDVIRALGGQI 143
>UniRef50_Q2PGG3 Cluster: Serine racemase; n=8; Magnoliophyta|Rep:
Serine racemase - Arabidopsis thaliana (Mouse-ear cress)
Length = 331
Score = 45.2 bits (102), Expect = 0.003
Identities = 43/180 (23%), Positives = 72/180 (40%), Gaps = 10/180 (5%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
+F KCE + GG+ K R + VL AK + +SGN ++LA + G
Sbjct: 45 LFFKCECLQKGGAFKFRGACNAVLSLDAEQAAKG---VVTHSSGNHAAALSLAAKIQGIP 101
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQYK 160
IV P K+ + G +V+ + A S E S ++L++ ++ Y
Sbjct: 102 AYIVVPKGAPKCKVDNVIRYGGKVIWSE--ATMSSREEIAS----KVLQETGSVLIHPY- 154
Query: 161 NDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDPQGS 220
ND + A E+L + ++D I A K P I+ +P+G+
Sbjct: 155 NDGRIISGQGTIALELLEQIQEIDAIVVPISGGGLISGVALAAKSIKPSIRIIAAEPKGA 214
>UniRef50_A3H9X3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Caldivirga maquilingensis IC-167|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Caldivirga maquilingensis IC-167
Length = 291
Score = 45.2 bits (102), Expect = 0.003
Identities = 45/155 (29%), Positives = 67/155 (43%), Gaps = 17/155 (10%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNP-GGSIKDRISYTMVLEAQKSGIAKSGTRFIEP 81
TPL++LN + ++AK EF+NP SIKDR + ++ + G G IE
Sbjct: 15 TPLLKLNLFKQR-----NVWAKLEFMNPLTHSIKDRTALGLI---KSLGNVDKGV--IEV 64
Query: 82 TSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLS 141
+SGN + +A G P + + L+G +VV+ E ++
Sbjct: 65 SSGNLAVALASILRARGIDYIAYVPSGSPRSFKVMLKLMGVKVVEREGNTSSILPE-VIN 123
Query: 142 VAKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEI 176
AK+ L PN Q+ N N HY TA EI
Sbjct: 124 EAKKLGLSHPN-----QFSNPANYMIHYNTTAREI 153
>UniRef50_Q8NRR7 Cluster: Threonine dehydratase; n=4;
Actinomycetales|Rep: Threonine dehydratase -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 310
Score = 44.8 bits (101), Expect = 0.005
Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 17/206 (8%)
Query: 40 EMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGF 99
+++ K EF+ G K R ++ L A ++G+ + + GN G+ A A A
Sbjct: 33 QIWIKAEFLQKCGVFKTRGAFNRQLAASENGLLDPTVGIVAASGGNAGLANAFAAASLSV 92
Query: 100 GCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSVAKRRLLEDPNAISCDQY 159
T++ P+ K+ + GA V Q + E +E F A + + A+ C Y
Sbjct: 93 PATVLVPETAPQVKVDRLKQYGATVQQIGS----EYAEAF--EAAQTFESETGALFCHAY 146
Query: 160 KNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQKVKEKCPKCIIVTVDP-- 217
+ + EI+ +PDVD I A V K +V V+P
Sbjct: 147 -DQPDIAAGAGVIGLEIVEDLPDVDTIVVAVGGGGLYAGIAAVVAAHDIK--VVAVEPSK 203
Query: 218 ----QGSLIFGEGPADLYFVEGIGGD 239
SLI G+ P D+ V GI D
Sbjct: 204 IPTLHNSLIAGQ-PVDVN-VSGIAAD 227
>UniRef50_Q89KX3 Cluster: Bll4777 protein; n=8; Bacteria|Rep:
Bll4777 protein - Bradyrhizobium japonicum
Length = 471
Score = 44.8 bits (101), Expect = 0.005
Identities = 35/102 (34%), Positives = 44/102 (43%), Gaps = 5/102 (4%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
TPL+RL ++ K G E+ K E P GS K R V + GI PT
Sbjct: 148 TPLIRLPKLGKKLG-GGEIIVKDEGRLPTGSFKARGLVMAVSMGKALGIKHMAM----PT 202
Query: 83 SGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEV 124
+GN G +A CG TI P + +S I L GA V
Sbjct: 203 NGNAGAALAAYATSCGIKTTIFCPADTPEVNVSEIELQGATV 244
>UniRef50_Q890M3 Cluster: Threonine dehydratase; n=13;
Firmicutes|Rep: Threonine dehydratase - Clostridium
tetani
Length = 405
Score = 44.8 bits (101), Expect = 0.005
Identities = 35/113 (30%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 14 NNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAK 73
NNI + + TPLV + K G ++ KCE G+ K R +Y ++ + K
Sbjct: 15 NNIKKVVRRTPLVYSSTFTKLTGYN--IYIKCENKQKTGAFKLRGAYNKIVSLNEEE-KK 71
Query: 74 SGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQ 126
G I ++GN GVA A + G TIV P K++ GA+V+Q
Sbjct: 72 KGV--IASSAGNHAQGVAYAASAFGINSTIVMPVTAPLAKVNATKGYGAKVIQ 122
>UniRef50_A3DLX2 Cluster: Threonine dehydratase; n=2;
Thermoprotei|Rep: Threonine dehydratase -
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 /
F1)
Length = 419
Score = 44.8 bits (101), Expect = 0.005
Identities = 39/114 (34%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 16 ILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRIS----YTMVLEAQKSGI 71
I E I TPLV I G C+ + K E + GS K R + Y ++ E + G
Sbjct: 27 IQEFIHKTPLVYNYTISNIVG--CDTYLKLENMQKTGSFKVRGATFKIYMLIKEYESRGE 84
Query: 72 AKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVV 125
G + +SGN GVA A V G IV P S K++ GAEVV
Sbjct: 85 KLPGV--VAASSGNHAQGVAYAAKVFGIPAIIVMPKTASSTKINATKSYGAEVV 136
>UniRef50_O94634 Cluster: Threonine ammonia-lyase; n=1;
Schizosaccharomyces pombe|Rep: Threonine ammonia-lyase -
Schizosaccharomyces pombe (Fission yeast)
Length = 600
Score = 44.4 bits (100), Expect = 0.006
Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 5/119 (4%)
Query: 7 FTRNRIYNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEA 66
+ R + +N+ E I +TPL + I + G+ ++ K E + P S K R ++ +
Sbjct: 98 YLRLTLTSNVYEVIKETPLTKGVVISESTGVP--VYLKREDLTPVFSFKIRGAHNKMASL 155
Query: 67 QKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVV 125
K + K+G I ++GN GVA + G TIV P + K + LGA V+
Sbjct: 156 DKQSL-KNGV--IACSAGNHAQGVAYSARTLGVKATIVMPQNTPEIKWRNVKRLGANVL 211
>UniRef50_Q124A5 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=11; Bacteria|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 335
Score = 44.0 bits (99), Expect = 0.008
Identities = 33/104 (31%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
TP R + G +C + K E P G+ K R T +KSG I T
Sbjct: 38 TPQYRWGLSSQRLGTDC--WIKHENHTPVGAFKIRGGLTYFDALKKSGTLP--LEVISAT 93
Query: 83 SGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQ 126
GN G + A G CTIV P NS EK + + LG +++
Sbjct: 94 RGNHGQSIGWAARAHGVACTIVVPHGNSIEKNAAMRALGVTLIE 137
>UniRef50_Q4PDX1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 387
Score = 44.0 bits (99), Expect = 0.008
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 41 MFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPTSGNTGIGVALATAVCGFG 100
+F K + P GS K R + + + T + + GN G+ VA A G G
Sbjct: 43 VFLKLDCDQPSGSFKIR-GIGAICQMAIAQHGAENTHLVSSSGGNAGLAVAHAAKSAGVG 101
Query: 101 CTIVTPDKNSDEKMSTISLLGAEVV 125
CTI P + + + L GAEVV
Sbjct: 102 CTIFVPLSTEADVVEKLRLQGAEVV 126
>UniRef50_A1S0F3 Cluster: Pyridoxal-5'-phosphate-dependent enzyme,
beta subunit; n=1; Thermofilum pendens Hrk 5|Rep:
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit -
Thermofilum pendens (strain Hrk 5)
Length = 325
Score = 44.0 bits (99), Expect = 0.008
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 7/115 (6%)
Query: 23 TPLVRLNRIPKDYGLE-CEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEP 81
TPL++L + K L+ ++ K E NP G+ KDR + V EA +G
Sbjct: 16 TPLLKLTSLRKLLNLDGAAVYLKYEGYNPTGTHKDRAALAHVGEAVLNGY----DTVTVG 71
Query: 82 TSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESS 136
T GN G+ VA + G I P S+ ++ + GA VV+ P+E +
Sbjct: 72 TCGNYGVAVAYYARLAGLRAVIFVPKGYSNSRVPEMKRYGARVVEVE--GPYEDA 124
>UniRef50_Q1YQF2 Cluster: Putative threonine dehydratase; n=1; gamma
proteobacterium HTCC2207|Rep: Putative threonine
dehydratase - gamma proteobacterium HTCC2207
Length = 126
Score = 43.6 bits (98), Expect = 0.011
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
+ I I TP+++ I K G CE++ K E + G+ K R V +A
Sbjct: 12 HERIKPHIHRTPIMQSQEINKLLG--CELYFKAENLQKLGAFKARGGCNAVFSMDAKSLA 69
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPD 107
K I +SGN G +A A A+ G CT+V P+
Sbjct: 70 KG---VITHSSGNHGAALAWAAALRGANCTVVMPE 101
>UniRef50_Q9V0P1 Cluster: Pyridoxal phosphate dependent enzyme; n=3;
Pyrococcus|Rep: Pyridoxal phosphate dependent enzyme -
Pyrococcus abyssi
Length = 439
Score = 43.6 bits (98), Expect = 0.011
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 21 GDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIE 80
G TPL++ RI + L ++F K E NP GS +DR++ + G+ + FI
Sbjct: 64 GGTPLIKA-RISEQ--LNVDVFIKDETRNPTGSFRDRLATVAI----SYGLPYAKNGFIV 116
Query: 81 PTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQ 126
+ GN VA +A C +V P K K+ + GA +++
Sbjct: 117 ASDGNAAASVAAYSARAEKECFVVIPRKVDKGKLIQMIAFGARIIR 162
>UniRef50_Q97CB2 Cluster: Threonine deaminase; n=4;
Thermoplasmatales|Rep: Threonine deaminase -
Thermoplasma volcanium
Length = 406
Score = 43.6 bits (98), Expect = 0.011
Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 20 IGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFI 79
+ TPL+R I K+YG +++ K E GS K R + + K + I
Sbjct: 23 VNRTPLIRSTTIGKEYG--ADIYFKLENFQKTGSFKSRGA---IFRFSKLSEDEKRHGVI 77
Query: 80 EPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVV 125
++GN GVA A + G IV P+ +K++ + GA V+
Sbjct: 78 TASAGNHAQGVAYAAMINGIDAKIVMPEYTIPQKVNAVISYGAHVI 123
>UniRef50_Q8ZVF0 Cluster: Threonine dehydratase; n=6;
Thermoproteaceae|Rep: Threonine dehydratase -
Pyrobaculum aerophilum
Length = 403
Score = 43.6 bits (98), Expect = 0.011
Identities = 71/299 (23%), Positives = 123/299 (41%), Gaps = 29/299 (9%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
TP +R + + G E+F K E + GS K R +Y + + K G + FI +
Sbjct: 23 TPTLRSESLTRITG--GEVFLKLESLQKTGSFKIRGAYFAMYKYIKEGYRE----FITAS 76
Query: 83 SGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFLSV 142
SGN GVA A + G T+V P+ K+ GA V+ E +
Sbjct: 77 SGNHAQGVAYAAQLHGVKATVVMPETTPWLKVKKTQDYGANVIL--------YGESYYEA 128
Query: 143 AKRRLLEDPNAISCDQYKNDVNPRTHYEYTAEEILALVPDVDMIXXXXXXXXXXXXXAQK 202
K+ + + ND + EI+ V DVD++ A
Sbjct: 129 EKKAMELVRGGVKFLHAYNDWYVISGQATLGLEIVEDVGDVDVVVVPIGGGGLISGVAYA 188
Query: 203 VKEKCPKCIIVTVDPQGS----LIFGEG-PADLYFV----EGIGGDFVPDV---LDKSVI 250
VK++ P ++ V G+ L EG P + V +GI D+ L + +
Sbjct: 189 VKKRRPGAKVIGVQASGAPAVYLSLKEGRPIVIEKVDTIADGIAIKSPGDITLKLIQEYV 248
Query: 251 DKVEKPNDYDAFNMSREIIKKEGLLCGGSSGAAMISAIRAAKKLNFGAGKRVVVILPDG 309
D V +D + + ++++ ++ G +GA ++A+ + K+N +GK+VV ++ G
Sbjct: 249 DDVVLVDDNEIVDAIYLLLERTRVVAEG-AGAVAVAALMSG-KINV-SGKKVVAVVSGG 304
>UniRef50_P25379 Cluster: Catabolic L-serine/threonine dehydratase
[Includes: L-serine dehydratase (EC 4.3.1.17) (L-serine
deaminase); L-threonine dehydratase (EC 4.3.1.19)
(L-threonine deaminase)]; n=5; Saccharomycetaceae|Rep:
Catabolic L-serine/threonine dehydratase [Includes:
L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase);
L-threonine dehydratase (EC 4.3.1.19) (L-threonine
deaminase)] - Saccharomyces cerevisiae (Baker's yeast)
Length = 360
Score = 43.6 bits (98), Expect = 0.011
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 8/105 (7%)
Query: 40 EMFAKCEFVNPGGSIKDRISYTMVLEA----QKSGIAKSGTRFIEPTSGNTGIGVALATA 95
+ F K E + P GS K R +++++ QK G K + + GN G A A
Sbjct: 22 QFFLKYECLQPSGSFKSRGIGNLIMKSAIRIQKDG--KRSPQVFASSGGNAGFAAATACQ 79
Query: 96 VCGFGCTIVTPDKNSDEKMSTISLLGAEVVQTPAMAPWESSEHFL 140
CT+V P + I GA+V+ + A W+ ++ FL
Sbjct: 80 RLSLPCTVVVPTATKKRMVDKIRNTGAQVIVSGAY--WKEADTFL 122
>UniRef50_Q96GA7 Cluster: Serine dehydratase-like; n=29;
Eumetazoa|Rep: Serine dehydratase-like - Homo sapiens
(Human)
Length = 329
Score = 43.6 bits (98), Expect = 0.011
Identities = 37/106 (34%), Positives = 49/106 (46%), Gaps = 8/106 (7%)
Query: 23 TPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIAKSGTRFIEPT 82
TPL+ + + G+ +F KCE V P GS K R E +AK G R + +
Sbjct: 18 TPLLESWALSQVAGMP--VFLKCENVQPSGSFKIRGIGHFCQE-----MAKKGCRHLVCS 70
Query: 83 SG-NTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT 127
SG N GI A A G TIV P+ S + + + GAEV T
Sbjct: 71 SGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLT 116
>UniRef50_Q92HZ2 Cluster: Threonine dehydratase [EC:4.2.1.16]; n=12;
Rickettsieae|Rep: Threonine dehydratase [EC:4.2.1.16] -
Rickettsia conorii
Length = 343
Score = 43.2 bits (97), Expect = 0.014
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
Query: 13 YNNILETIGDTPLVRLNRIPKDYGLECEMFAKCEFVNPGGSIKDRISYTMVLEAQKSGIA 72
+N I + + TP+V + + G E +F K E + G+ K R +LE ++ G
Sbjct: 15 HNRIKQYLHLTPIVHSESLNEMLGHE--IFFKVESLQKTGAFKVRGVLNHLLELKEQG-- 70
Query: 73 KSGTRFIEPTSGNTGIGVALATAVCGFGCTIVTPDKNSDEKMSTISLLGAEVVQT 127
K + + ++GN GIG+A A+ + G I P S K G EV+ T
Sbjct: 71 KLPDKIVGYSTGNHGIGLAYASKLFGIKTRIYLPLNTSKVKQQAALYYGGEVIYT 125
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.137 0.402
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 495,734,707
Number of Sequences: 1657284
Number of extensions: 20618074
Number of successful extensions: 45847
Number of sequences better than 10.0: 365
Number of HSP's better than 10.0 without gapping: 216
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 45063
Number of HSP's gapped (non-prelim): 421
length of query: 440
length of database: 575,637,011
effective HSP length: 103
effective length of query: 337
effective length of database: 404,936,759
effective search space: 136463687783
effective search space used: 136463687783
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 74 (33.9 bits)
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