Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000063-TA|BGIBMGA000063-PA|IPR000488|Death,
IPR000719|Protein kinase, IPR011009|Protein kinase-like,
IPR011029|DEATH-like, IPR008271|Serine/threonine protein kinase,
active site, IPR002290|Serine/threonine protein kinase
(361 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L76191-1|AAC41949.1| 712|Homo sapiens interleukin-1 receptor-as... 126 9e-29
DQ054788-1|AAY88246.1| 633|Homo sapiens interleukin-1 receptor ... 126 9e-29
BC054000-1|AAH54000.1| 693|Homo sapiens IRAK1 protein protein. 126 9e-29
BC014963-1|AAH14963.1| 633|Homo sapiens interleukin-1 receptor-... 126 9e-29
AF346607-1|AAK62888.1| 682|Homo sapiens interleukin-1 receptor ... 126 9e-29
AF030876-1|AAC08756.1| 712|Homo sapiens Interleukin 1 receptor-... 126 9e-29
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 124 5e-28
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 124 5e-28
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 124 5e-28
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 124 5e-28
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 124 5e-28
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 124 5e-28
AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase... 124 5e-28
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 122 1e-27
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 121 5e-27
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 121 5e-27
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 121 5e-27
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 121 5e-27
AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens ... 121 5e-27
BC069388-1|AAH69388.1| 596|Homo sapiens interleukin-1 receptor-... 110 8e-24
BC057800-1|AAH57800.1| 596|Homo sapiens interleukin-1 receptor-... 110 8e-24
AF113136-1|AAD40879.1| 596|Homo sapiens IL-1 receptor-associate... 110 8e-24
BC125184-1|AAI25185.1| 625|Homo sapiens interleukin-1 receptor-... 88 4e-17
AJ496794-1|CAD43180.3| 625|Homo sapiens interleukin-1 receptor ... 88 4e-17
AF026273-1|AAB87669.1| 590|Homo sapiens interleukin-1 receptor-... 88 4e-17
DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated prote... 83 2e-15
BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated prote... 83 2e-15
BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated prote... 83 2e-15
BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated prote... 83 2e-15
AL121964-4|CAI19612.1| 606|Homo sapiens mitogen-activated prote... 83 2e-15
AL121964-3|CAI19611.1| 579|Homo sapiens mitogen-activated prote... 83 2e-15
AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated prote... 83 2e-15
AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated prote... 83 2e-15
AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated prote... 83 2e-15
AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated prote... 83 2e-15
AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated prote... 83 2e-15
AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated prote... 83 2e-15
AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kina... 83 2e-15
AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kina... 83 2e-15
AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kina... 83 2e-15
AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kina... 83 2e-15
AY283670-1|AAP57089.1| 292|Homo sapiens interleukin-1 receptor ... 81 6e-15
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 79 3e-14
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 79 3e-14
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 79 3e-14
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 79 3e-14
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 79 3e-14
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 79 3e-14
U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein ... 78 6e-14
L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein. 78 6e-14
BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated prote... 78 6e-14
BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated prote... 78 6e-14
AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated prote... 78 6e-14
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 75 3e-13
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 75 3e-13
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 75 3e-13
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 75 3e-13
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 75 3e-13
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 75 3e-13
AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4 ... 74 7e-13
AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4 ... 74 7e-13
AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4b... 74 7e-13
AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase 4a... 74 7e-13
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 73 1e-12
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 72 3e-12
D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein. 72 3e-12
BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein. 72 3e-12
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 72 3e-12
BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein. 72 3e-12
BC004553-1|AAH04553.1| 540|Homo sapiens receptor-interacting se... 72 3e-12
AY358814-1|AAQ89173.1| 540|Homo sapiens RIPK2 protein. 72 3e-12
AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase ... 72 3e-12
AF078530-1|AAC27722.1| 540|Homo sapiens receptor interacting pr... 72 3e-12
AF064824-1|AAC25668.1| 540|Homo sapiens CARD-containing ICE ass... 72 3e-12
AF027706-1|AAC34970.1| 540|Homo sapiens serine/threonine kinase... 72 3e-12
AC004003-1|AAC24561.1| 540|Homo sapiens WUGSC:H_RG437L15.1 prot... 72 3e-12
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 72 4e-12
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 71 5e-12
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 71 5e-12
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 71 5e-12
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 71 5e-12
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 71 6e-12
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 71 6e-12
AY524045-1|AAS94254.1| 540|Homo sapiens GIG30 protein. 71 6e-12
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 71 6e-12
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 71 6e-12
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 71 6e-12
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 71 6e-12
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 71 8e-12
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 71 8e-12
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 71 8e-12
BC062584-1|AAH62584.1| 518|Homo sapiens receptor-interacting se... 69 2e-11
AY494983-1|AAS75517.1| 231|Homo sapiens RIP3 gamma protein. 69 2e-11
AY494982-1|AAS75516.1| 252|Homo sapiens RIP3 beta protein. 69 2e-11
AY453693-1|AAS16359.1| 518|Homo sapiens receptor interacting pr... 69 2e-11
AK075275-1|BAC11512.1| 427|Homo sapiens protein ( Homo sapiens ... 69 2e-11
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 69 3e-11
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 69 3e-11
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 69 3e-11
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 69 3e-11
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 69 3e-11
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 69 3e-11
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 69 3e-11
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 68 6e-11
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 68 6e-11
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 68 6e-11
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 68 6e-11
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 68 6e-11
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 68 6e-11
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 68 6e-11
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 68 6e-11
D45906-1|BAA08312.1| 638|Homo sapiens LIMK-2 protein. 67 1e-10
CR456513-1|CAG30399.1| 638|Homo sapiens LIMK2 protein. 67 1e-10
BC013051-1|AAH13051.1| 686|Homo sapiens LIM domain kinase 2 pro... 67 1e-10
AC002073-3|AAB54055.1| 733|Homo sapiens Lim kinase protein. 67 1e-10
AC002073-2|AAB54056.1| 638|Homo sapiens Lim Kinase protein. 67 1e-10
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 66 1e-10
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 66 1e-10
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 66 1e-10
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-10
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-10
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 66 1e-10
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 66 1e-10
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-10
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 66 1e-10
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-10
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-10
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 66 1e-10
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 66 1e-10
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 66 2e-10
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 66 2e-10
L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kina... 66 2e-10
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 66 2e-10
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 66 2e-10
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein. 66 2e-10
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 66 2e-10
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 66 2e-10
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 66 2e-10
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 66 2e-10
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 66 2e-10
AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens ... 66 2e-10
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 66 2e-10
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 66 2e-10
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 66 2e-10
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 66 2e-10
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 66 2e-10
AB209655-1|BAD92892.1| 310|Homo sapiens mitogen-activated prote... 66 2e-10
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 65 3e-10
U50062-1|AAC32232.1| 671|Homo sapiens RIP protein kinase protein. 65 3e-10
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 65 3e-10
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 65 3e-10
BC126256-1|AAI26257.1| 671|Homo sapiens receptor (TNFRSF)-inter... 65 3e-10
BC126254-1|AAI26255.1| 671|Homo sapiens receptor (TNFRSF)-inter... 65 3e-10
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 65 3e-10
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 65 3e-10
AY682848-1|AAT74626.1| 671|Homo sapiens receptor (TNFRSF)-inter... 65 3e-10
AL031963-3|CAD70625.1| 671|Homo sapiens receptor (TNFRSF)-inter... 65 3e-10
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 65 3e-10
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 65 4e-10
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 65 4e-10
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 65 4e-10
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 65 4e-10
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 65 4e-10
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 65 4e-10
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 65 4e-10
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 65 4e-10
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 64 6e-10
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 64 7e-10
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 64 7e-10
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 64 7e-10
U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein. 64 7e-10
U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein. 64 7e-10
U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced LIM... 64 7e-10
U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein. 64 7e-10
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 64 7e-10
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 64 7e-10
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 64 7e-10
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 64 7e-10
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 64 7e-10
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 64 7e-10
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 64 7e-10
D26309-1|BAA05371.1| 647|Homo sapiens LIM kinase protein. 64 7e-10
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 64 7e-10
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 64 7e-10
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 64 7e-10
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 64 7e-10
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 64 7e-10
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 64 7e-10
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 64 7e-10
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 64 7e-10
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 64 7e-10
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 64 7e-10
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 64 7e-10
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 64 7e-10
AC005057-3|AAS07438.1| 596|Homo sapiens unknown protein. 64 7e-10
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 64 1e-09
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 64 1e-09
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 64 1e-09
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 64 1e-09
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 64 1e-09
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 64 1e-09
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 64 1e-09
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 64 1e-09
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 64 1e-09
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 64 1e-09
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 64 1e-09
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 64 1e-09
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 64 1e-09
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protei... 64 1e-09
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 64 1e-09
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 64 1e-09
AF156884-1|AAD39005.1| 518|Homo sapiens RIP-like kinase protein. 64 1e-09
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 64 1e-09
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 64 1e-09
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 63 1e-09
Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine pro... 63 1e-09
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 63 1e-09
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 63 1e-09
DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated prote... 63 1e-09
BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated prote... 63 1e-09
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 63 1e-09
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 63 1e-09
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 63 1e-09
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 63 1e-09
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 63 1e-09
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 63 2e-09
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 63 2e-09
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 63 2e-09
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 63 2e-09
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 63 2e-09
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 63 2e-09
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 63 2e-09
BC127603-1|AAI27604.1| 829|Homo sapiens kinase suppressor of ra... 63 2e-09
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 63 2e-09
BC107107-1|AAI07108.1| 827|Homo sapiens KSR2 protein protein. 63 2e-09
BC107106-1|AAI07107.1| 827|Homo sapiens KSR2 protein protein. 63 2e-09
AY345972-1|AAQ24226.1| 829|Homo sapiens kinase suppressor of Ra... 63 2e-09
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 63 2e-09
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 63 2e-09
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 63 2e-09
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 63 2e-09
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 63 2e-09
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 63 2e-09
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 62 2e-09
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 62 2e-09
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 62 2e-09
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 62 2e-09
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 62 2e-09
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 62 2e-09
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 62 2e-09
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 62 2e-09
BC008884-1|AAH08884.1| 352|Homo sapiens TNK2 protein protein. 62 2e-09
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 62 2e-09
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 62 2e-09
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 62 3e-09
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 62 3e-09
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 62 3e-09
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 62 3e-09
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 62 3e-09
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 62 3e-09
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 62 3e-09
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 62 3e-09
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 62 3e-09
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 62 3e-09
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 62 3e-09
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 62 3e-09
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 62 3e-09
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 62 3e-09
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 62 3e-09
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 62 3e-09
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 62 3e-09
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 62 3e-09
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 62 3e-09
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 62 4e-09
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 62 4e-09
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 62 4e-09
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 62 4e-09
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 62 4e-09
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 62 4e-09
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 62 4e-09
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 62 4e-09
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 62 4e-09
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 62 4e-09
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 62 4e-09
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 62 4e-09
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 62 4e-09
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 62 4e-09
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 62 4e-09
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 62 4e-09
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 61 5e-09
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 61 5e-09
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 61 5e-09
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 61 5e-09
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 61 5e-09
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 61 5e-09
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 61 5e-09
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 61 5e-09
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 61 7e-09
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 61 7e-09
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 61 7e-09
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 61 7e-09
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 61 7e-09
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 61 7e-09
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 61 7e-09
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 61 7e-09
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 61 7e-09
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 60 9e-09
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 60 9e-09
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 60 9e-09
AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-... 60 9e-09
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 60 1e-08
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 60 1e-08
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 60 1e-08
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 60 2e-08
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 60 2e-08
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 60 2e-08
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 60 2e-08
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 60 2e-08
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 60 2e-08
AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein. 60 2e-08
AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein. 60 2e-08
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 59 2e-08
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 59 2e-08
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 59 3e-08
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 59 3e-08
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 59 3e-08
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 59 3e-08
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 59 3e-08
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 59 3e-08
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 59 3e-08
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 59 3e-08
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 59 3e-08
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 59 3e-08
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 59 3e-08
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 59 3e-08
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 59 3e-08
BC035782-1|AAH35782.1| 661|Homo sapiens TNK1 protein protein. 59 3e-08
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 59 3e-08
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 59 3e-08
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 59 3e-08
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 59 3e-08
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 59 3e-08
AF097738-1|AAC99412.1| 661|Homo sapiens non-receptor tyosine ki... 59 3e-08
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 59 3e-08
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 59 3e-08
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 59 3e-08
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 59 3e-08
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 58 4e-08
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 58 4e-08
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 58 4e-08
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 58 4e-08
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 58 4e-08
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 58 4e-08
DQ445915-1|ABE03013.1| 435|Homo sapiens mitogen-activated prote... 58 4e-08
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 58 4e-08
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 58 4e-08
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 58 4e-08
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 58 4e-08
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 58 4e-08
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 58 4e-08
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 58 4e-08
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 58 4e-08
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 58 4e-08
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 58 4e-08
BC044925-1|AAH44925.2| 830|Homo sapiens TLK2 protein protein. 58 4e-08
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 58 4e-08
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 58 4e-08
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 58 4e-08
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 58 4e-08
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 58 4e-08
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 58 4e-08
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 58 4e-08
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 58 4e-08
AF162667-1|AAF03095.1| 749|Homo sapiens tousled-like kinase 2 p... 58 4e-08
AB004884-1|BAA20561.1| 719|Homo sapiens PKU-alpha protein. 58 4e-08
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 58 5e-08
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 58 5e-08
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 58 5e-08
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 58 5e-08
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 58 5e-08
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 58 5e-08
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 58 5e-08
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 58 5e-08
BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein k... 58 5e-08
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 58 5e-08
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 58 5e-08
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 58 5e-08
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 58 5e-08
BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase ... 58 5e-08
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 58 5e-08
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 58 5e-08
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 58 5e-08
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 58 5e-08
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 58 6e-08
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 58 6e-08
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 58 6e-08
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 58 6e-08
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 57 8e-08
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 57 8e-08
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 57 1e-07
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 57 1e-07
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 57 1e-07
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 57 1e-07
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 57 1e-07
AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase ... 57 1e-07
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 56 1e-07
U43408-1|AAC50427.1| 666|Homo sapiens tyrosine kinase protein. 56 1e-07
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 56 1e-07
L05624-1|AAA36318.1| 393|Homo sapiens MAP kinase kinase protein. 56 1e-07
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 56 1e-07
BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein pr... 56 1e-07
BC139729-1|AAI39730.1| 393|Homo sapiens mitogen-activated prote... 56 1e-07
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 56 1e-07
BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase ... 56 1e-07
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 56 1e-07
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 56 2e-07
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 56 2e-07
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 56 2e-07
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 56 2e-07
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 56 2e-07
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 56 2e-07
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 56 2e-07
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 56 2e-07
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 56 2e-07
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 56 2e-07
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 56 2e-07
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 56 2e-07
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 56 2e-07
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 56 2e-07
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 56 2e-07
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 56 2e-07
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 56 2e-07
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 56 2e-07
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 56 2e-07
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 56 2e-07
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 56 2e-07
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 56 2e-07
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 56 2e-07
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 56 2e-07
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 56 2e-07
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 56 3e-07
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 56 3e-07
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 56 3e-07
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 56 3e-07
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 56 3e-07
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 56 3e-07
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 56 3e-07
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 56 3e-07
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 55 3e-07
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 55 3e-07
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 55 3e-07
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 55 3e-07
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 55 3e-07
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 55 3e-07
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 55 3e-07
BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and... 55 3e-07
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 55 3e-07
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 55 3e-07
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 55 3e-07
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 55 3e-07
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 55 3e-07
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 55 3e-07
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 55 3e-07
AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage kinase-re... 55 3e-07
AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage kinase-re... 55 3e-07
AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppres... 55 3e-07
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 55 3e-07
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 55 3e-07
AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase pr... 55 3e-07
AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and... 55 3e-07
AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZA... 55 3e-07
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 55 3e-07
AB209118-1|BAD92355.1| 781|Homo sapiens BDNF/NT-3 growth factor... 55 3e-07
AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage... 55 3e-07
AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein. 55 3e-07
AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein. 55 3e-07
AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage... 55 3e-07
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 55 3e-07
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 55 3e-07
Z14138-1|CAA78512.1| 467|Homo sapiens protein ( H.sapiens (Ewin... 55 4e-07
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 55 4e-07
U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein. 55 4e-07
U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein. 55 4e-07
U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein. 55 4e-07
U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein. 55 4e-07
>L76191-1|AAC41949.1| 712|Homo sapiens interleukin-1
receptor-associated kinase protein.
Length = 712
Score = 126 bits (305), Expect = 9e-29
Identities = 72/161 (44%), Positives = 95/161 (59%), Gaps = 8/161 (4%)
Query: 164 ELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQ---- 219
E+ T ++SE +G GGFG VY+ + AVKRL++N + V++ L +
Sbjct: 204 EISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQL 263
Query: 220 --YRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAP-LSWAQRCRIMCGVA 276
+RH NI+ GY CLVY + GSLE RL + A P LSW QR I+ G A
Sbjct: 264 SRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTA 323
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R +QFLH + S LIHGDIK +N+LLD+ L PK+GDFGLAR
Sbjct: 324 RAIQFLHQDSPS-LIHGDIKSSNVLLDERLTPKLGDFGLAR 363
>DQ054788-1|AAY88246.1| 633|Homo sapiens interleukin-1 receptor
associated-kinase 1 splice variant c protein.
Length = 633
Score = 126 bits (305), Expect = 9e-29
Identities = 72/161 (44%), Positives = 95/161 (59%), Gaps = 8/161 (4%)
Query: 164 ELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQ---- 219
E+ T ++SE +G GGFG VY+ + AVKRL++N + V++ L +
Sbjct: 204 EISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQL 263
Query: 220 --YRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAP-LSWAQRCRIMCGVA 276
+RH NI+ GY CLVY + GSLE RL + A P LSW QR I+ G A
Sbjct: 264 SRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTA 323
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R +QFLH + S LIHGDIK +N+LLD+ L PK+GDFGLAR
Sbjct: 324 RAIQFLHQDSPS-LIHGDIKSSNVLLDERLTPKLGDFGLAR 363
>BC054000-1|AAH54000.1| 693|Homo sapiens IRAK1 protein protein.
Length = 693
Score = 126 bits (305), Expect = 9e-29
Identities = 72/161 (44%), Positives = 95/161 (59%), Gaps = 8/161 (4%)
Query: 164 ELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQ---- 219
E+ T ++SE +G GGFG VY+ + AVKRL++N + V++ L +
Sbjct: 230 EISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQL 289
Query: 220 --YRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAP-LSWAQRCRIMCGVA 276
+RH NI+ GY CLVY + GSLE RL + A P LSW QR I+ G A
Sbjct: 290 SRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTA 349
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R +QFLH + S LIHGDIK +N+LLD+ L PK+GDFGLAR
Sbjct: 350 RAIQFLHQDSPS-LIHGDIKSSNVLLDERLTPKLGDFGLAR 389
>BC014963-1|AAH14963.1| 633|Homo sapiens interleukin-1
receptor-associated kinase 1 protein.
Length = 633
Score = 126 bits (305), Expect = 9e-29
Identities = 72/161 (44%), Positives = 95/161 (59%), Gaps = 8/161 (4%)
Query: 164 ELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQ---- 219
E+ T ++SE +G GGFG VY+ + AVKRL++N + V++ L +
Sbjct: 204 EISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQL 263
Query: 220 --YRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAP-LSWAQRCRIMCGVA 276
+RH NI+ GY CLVY + GSLE RL + A P LSW QR I+ G A
Sbjct: 264 SRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTA 323
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R +QFLH + S LIHGDIK +N+LLD+ L PK+GDFGLAR
Sbjct: 324 RAIQFLHQDSPS-LIHGDIKSSNVLLDERLTPKLGDFGLAR 363
>AF346607-1|AAK62888.1| 682|Homo sapiens interleukin-1 receptor
associated kinase 1b protein.
Length = 682
Score = 126 bits (305), Expect = 9e-29
Identities = 72/161 (44%), Positives = 95/161 (59%), Gaps = 8/161 (4%)
Query: 164 ELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQ---- 219
E+ T ++SE +G GGFG VY+ + AVKRL++N + V++ L +
Sbjct: 204 EISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQL 263
Query: 220 --YRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAP-LSWAQRCRIMCGVA 276
+RH NI+ GY CLVY + GSLE RL + A P LSW QR I+ G A
Sbjct: 264 SRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTA 323
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R +QFLH + S LIHGDIK +N+LLD+ L PK+GDFGLAR
Sbjct: 324 RAIQFLHQDSPS-LIHGDIKSSNVLLDERLTPKLGDFGLAR 363
>AF030876-1|AAC08756.1| 712|Homo sapiens Interleukin 1
receptor-associated kinase 1 protein.
Length = 712
Score = 126 bits (305), Expect = 9e-29
Identities = 72/161 (44%), Positives = 95/161 (59%), Gaps = 8/161 (4%)
Query: 164 ELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQ---- 219
E+ T ++SE +G GGFG VY+ + AVKRL++N + V++ L +
Sbjct: 204 EISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQL 263
Query: 220 --YRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAP-LSWAQRCRIMCGVA 276
+RH NI+ GY CLVY + GSLE RL + A P LSW QR I+ G A
Sbjct: 264 SRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTA 323
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R +QFLH + S LIHGDIK +N+LLD+ L PK+GDFGLAR
Sbjct: 324 RAIQFLHQDSPS-LIHGDIKSSNVLLDERLTPKLGDFGLAR 363
>BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 124 bits (299), Expect = 5e-28
Identities = 102/281 (36%), Positives = 137/281 (48%), Gaps = 22/281 (7%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N + +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA 276
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I G A
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAA 296
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 297 NGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 334
>AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor
associated kinase-4 protein.
Length = 460
Score = 124 bits (299), Expect = 5e-28
Identities = 102/281 (36%), Positives = 137/281 (48%), Gaps = 22/281 (7%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N + +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA 276
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I G A
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAA 296
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 297 NGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 334
>AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 variant protein.
Length = 460
Score = 124 bits (299), Expect = 5e-28
Identities = 102/281 (36%), Positives = 137/281 (48%), Gaps = 22/281 (7%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N + +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA 276
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I G A
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAA 296
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 297 NGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 334
>AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 124 bits (299), Expect = 5e-28
Identities = 102/281 (36%), Positives = 137/281 (48%), Gaps = 22/281 (7%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N + +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA 276
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I G A
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAA 296
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 297 NGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 334
>AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 124 bits (299), Expect = 5e-28
Identities = 102/281 (36%), Positives = 137/281 (48%), Gaps = 22/281 (7%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N + +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA 276
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I G A
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAA 296
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 297 NGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 334
>AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens
cDNA FLJ20521 fis, clone KAT10395. ).
Length = 460
Score = 124 bits (299), Expect = 5e-28
Identities = 102/281 (36%), Positives = 137/281 (48%), Gaps = 22/281 (7%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N + +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA 276
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I G A
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAA 296
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 297 NGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 334
>AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase
NY-REN-64 antigen protein.
Length = 460
Score = 124 bits (299), Expect = 5e-28
Identities = 102/281 (36%), Positives = 137/281 (48%), Gaps = 22/281 (7%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N + +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA 276
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I G A
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAA 296
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 297 NGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 334
>AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor
associated kinase 4 protein.
Length = 460
Score = 122 bits (295), Expect = 1e-27
Identities = 102/281 (36%), Positives = 136/281 (48%), Gaps = 22/281 (7%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTAGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA 276
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I G A
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAA 296
Query: 277 RGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 297 NGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 334
>AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 4
protein.
Length = 336
Score = 121 bits (291), Expect = 5e-27
Identities = 74/169 (43%), Positives = 96/169 (56%), Gaps = 15/169 (8%)
Query: 161 SYEELRLATDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQ 209
S+ EL+ T+++ ER N +G GGFG VYKG VAVK+L E Q
Sbjct: 45 SFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQ 104
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
+ +E+ + + +H+N++ L G+S G + CLVY M GSL RL DG PLSW R
Sbjct: 105 QFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
C+I G A G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 165 CKIAQGAANGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 210
>AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 3
protein.
Length = 336
Score = 121 bits (291), Expect = 5e-27
Identities = 74/169 (43%), Positives = 96/169 (56%), Gaps = 15/169 (8%)
Query: 161 SYEELRLATDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQ 209
S+ EL+ T+++ ER N +G GGFG VYKG VAVK+L E Q
Sbjct: 45 SFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQ 104
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
+ +E+ + + +H+N++ L G+S G + CLVY M GSL RL DG PLSW R
Sbjct: 105 QFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
C+I G A G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 165 CKIAQGAANGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 210
>AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 2
protein.
Length = 336
Score = 121 bits (291), Expect = 5e-27
Identities = 74/169 (43%), Positives = 96/169 (56%), Gaps = 15/169 (8%)
Query: 161 SYEELRLATDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQ 209
S+ EL+ T+++ ER N +G GGFG VYKG VAVK+L E Q
Sbjct: 45 SFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQ 104
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
+ +E+ + + +H+N++ L G+S G + CLVY M GSL RL DG PLSW R
Sbjct: 105 QFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
C+I G A G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 165 CKIAQGAANGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 210
>AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 1
protein.
Length = 336
Score = 121 bits (291), Expect = 5e-27
Identities = 74/169 (43%), Positives = 96/169 (56%), Gaps = 15/169 (8%)
Query: 161 SYEELRLATDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQ 209
S+ EL+ T+++ ER N +G GGFG VYKG VAVK+L E Q
Sbjct: 45 SFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQ 104
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
+ +E+ + + +H+N++ L G+S G + CLVY M GSL RL DG PLSW R
Sbjct: 105 QFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
C+I G A G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 165 CKIAQGAANGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 210
>AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens
cDNA FLJ14395 fis, clone HEMBA1003250, weakly similar to
PROTEIN KINASE APK1A (EC 2.7.1.-). ).
Length = 277
Score = 121 bits (291), Expect = 5e-27
Identities = 74/169 (43%), Positives = 96/169 (56%), Gaps = 15/169 (8%)
Query: 161 SYEELRLATDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQ 209
S+ EL+ T+++ ER N +G GGFG VYKG VAVK+L E Q
Sbjct: 45 SFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQ 104
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
+ +E+ + + +H+N++ L G+S G + CLVY M GSL RL DG PLSW R
Sbjct: 105 QFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
C+I G A G+ FLH + IH DIK ANILLD+ KI DFGLAR
Sbjct: 165 CKIAQGAANGINFLHE---NHHIHRDIKSANILLDEAFTAKISDFGLAR 210
>BC069388-1|AAH69388.1| 596|Homo sapiens interleukin-1
receptor-associated kinase 3 protein.
Length = 596
Score = 110 bits (264), Expect = 8e-24
Identities = 94/323 (29%), Positives = 153/323 (47%), Gaps = 33/323 (10%)
Query: 3 IYELPPEINKELCRLLDNFDY---WEELAGNYMMYTAMDVIEIKEKARHQGISPTEYLLE 59
+++LPP + ELC +LD+ D W LA + + +DV I EK QG S T LL
Sbjct: 17 LFDLPPALLGELCAVLDSCDGALGWRGLAER-LSSSWLDVRHI-EKYVDQGKSGTRELLW 74
Query: 60 CWGQKNHRIEELFVLLYRMKHIPAMRRLTGVVHERFHRLLHKLEAGNGQDGNNARTGGAQ 119
W QKN I +L +L M H A+ +T + +L E Q+G +
Sbjct: 75 SWAQKNKTIGDLLQVLQEMGHRRAIHLITN-----YGAVLSPSEKSY-QEGGFPNILFKE 128
Query: 120 RATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLG 179
A + D+V +P ++++ +L+ +S++ + T ++ + L+G
Sbjct: 129 TANVTVDNVLIP-----------EHNEKGVLLKS-----SISFQNIIEGTRNFHKDFLIG 172
Query: 180 RGGFGQVYKGEWKLLGVAVKRLRDNEGRD-----QELVREM-CLNQYRHDNILPLYGYSL 233
G +VY+ E + L AVK + + + + E+ L + H NIL L Y
Sbjct: 173 EGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFT 232
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
+ CL+Y M G+L RL+ APL W R I+ G+++ + +LH + ++I G
Sbjct: 233 ETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICG 292
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
I ANILLD +PK+ DF +A
Sbjct: 293 SISSANILLDDQFQPKLTDFAMA 315
>BC057800-1|AAH57800.1| 596|Homo sapiens interleukin-1
receptor-associated kinase 3 protein.
Length = 596
Score = 110 bits (264), Expect = 8e-24
Identities = 94/323 (29%), Positives = 153/323 (47%), Gaps = 33/323 (10%)
Query: 3 IYELPPEINKELCRLLDNFDY---WEELAGNYMMYTAMDVIEIKEKARHQGISPTEYLLE 59
+++LPP + ELC +LD+ D W LA + + +DV I EK QG S T LL
Sbjct: 17 LFDLPPALLGELCAVLDSCDGALGWRGLAER-LSSSWLDVRHI-EKYVDQGKSGTRELLW 74
Query: 60 CWGQKNHRIEELFVLLYRMKHIPAMRRLTGVVHERFHRLLHKLEAGNGQDGNNARTGGAQ 119
W QKN I +L +L M H A+ +T + +L E Q+G +
Sbjct: 75 SWAQKNKTIGDLLQVLQEMGHRRAIHLITN-----YGAVLSPSEKSY-QEGGFPNILFKE 128
Query: 120 RATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLG 179
A + D+V +P ++++ +L+ +S++ + T ++ + L+G
Sbjct: 129 TANVTVDNVLIP-----------EHNEKGVLLKS-----SISFQNIIEGTRNFHKDFLIG 172
Query: 180 RGGFGQVYKGEWKLLGVAVKRLRDNEGRD-----QELVREM-CLNQYRHDNILPLYGYSL 233
G +VY+ E + L AVK + + + + E+ L + H NIL L Y
Sbjct: 173 EGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFT 232
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
+ CL+Y M G+L RL+ APL W R I+ G+++ + +LH + ++I G
Sbjct: 233 ETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICG 292
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
I ANILLD +PK+ DF +A
Sbjct: 293 SISSANILLDDQFQPKLTDFAMA 315
>AF113136-1|AAD40879.1| 596|Homo sapiens IL-1
receptor-associated-kinase-M protein.
Length = 596
Score = 110 bits (264), Expect = 8e-24
Identities = 94/323 (29%), Positives = 153/323 (47%), Gaps = 33/323 (10%)
Query: 3 IYELPPEINKELCRLLDNFDY---WEELAGNYMMYTAMDVIEIKEKARHQGISPTEYLLE 59
+++LPP + ELC +LD+ D W LA + + +DV I EK QG S T LL
Sbjct: 17 LFDLPPALLGELCAVLDSCDGALGWRGLAER-LSSSWLDVRHI-EKYVDQGKSGTRELLW 74
Query: 60 CWGQKNHRIEELFVLLYRMKHIPAMRRLTGVVHERFHRLLHKLEAGNGQDGNNARTGGAQ 119
W QKN I +L +L M H A+ +T + +L E Q+G +
Sbjct: 75 SWAQKNKTIGDLLQVLQEMGHRRAIHLITN-----YGAVLSPSEKSY-QEGGFPNILFKE 128
Query: 120 RATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLG 179
A + D+V +P ++++ +L+ +S++ + T ++ + L+G
Sbjct: 129 TANVTVDNVLIP-----------EHNEKGVLLKS-----SISFQNIIEGTRNFHKDFLIG 172
Query: 180 RGGFGQVYKGEWKLLGVAVKRLRDNEGRD-----QELVREM-CLNQYRHDNILPLYGYSL 233
G +VY+ E + L AVK + + + + E+ L + H NIL L Y
Sbjct: 173 EGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFT 232
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
+ CL+Y M G+L RL+ APL W R I+ G+++ + +LH + ++I G
Sbjct: 233 ETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICG 292
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
I ANILLD +PK+ DF +A
Sbjct: 293 SISSANILLDDQFQPKLTDFAMA 315
>BC125184-1|AAI25185.1| 625|Homo sapiens interleukin-1
receptor-associated kinase 2 protein.
Length = 625
Score = 88.2 bits (209), Expect = 4e-17
Identities = 55/182 (30%), Positives = 92/182 (50%), Gaps = 11/182 (6%)
Query: 136 DQDTSSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLG 195
D S K +++L S ++ ATDD+++ + +G F VY+G
Sbjct: 174 DSKDFSTSIPKQEKLLSLAGDSLFWSEADVVQATDDFNQNRKISQGTFADVYRGHRHGKP 233
Query: 196 VAVKRLRD----NEGRDQELVR---EMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGG 248
K+LR+ + G + + ++CL + H N+LP+ G+ +Y MA G
Sbjct: 234 FVFKKLRETACSSPGSIERFFQAELQICL-RCCHPNVLPVLGFCAARQFHSFIYPYMANG 292
Query: 249 SLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP 308
SL+ RL+ + G+ PL W QR I G+ +++LH G +IH ++K +N+LLDQ L P
Sbjct: 293 SLQDRLQGQGGSDPLPWPQRVSICSGLLCAVEYLH---GLEIIHSNVKSSNVLLDQNLTP 349
Query: 309 KI 310
K+
Sbjct: 350 KL 351
Score = 51.6 bits (118), Expect = 4e-06
Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 2 YIYELPPEINKELCRLLDNFDYWEELA-GNYMMYTAMDVIEIKEKARHQGISPTEYLLEC 60
YIY+LP + +LCR +D W+ + +Y++ + +IK R QG+S T LL
Sbjct: 4 YIYQLPSWVLDDLCRNMDALSEWDWMEFASYVITDLTQLRKIKSMERVQGVSITRELLWW 63
Query: 61 WGQKNHRIEELFVLLYRMK 79
WG + +++L LL R++
Sbjct: 64 WGMRQATVQQLVDLLCRLE 82
>AJ496794-1|CAD43180.3| 625|Homo sapiens interleukin-1 receptor
associated kinase-2 protein.
Length = 625
Score = 88.2 bits (209), Expect = 4e-17
Identities = 55/182 (30%), Positives = 92/182 (50%), Gaps = 11/182 (6%)
Query: 136 DQDTSSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLG 195
D S K +++L S ++ ATDD+++ + +G F VY+G
Sbjct: 174 DSKDFSTSIPKQEKLLSLAGDSLFWSEADVVQATDDFNQNRKISQGTFADVYRGHRHGKP 233
Query: 196 VAVKRLRD----NEGRDQELVR---EMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGG 248
K+LR+ + G + + ++CL + H N+LP+ G+ +Y MA G
Sbjct: 234 FVFKKLRETACSSPGSIERFFQAELQICL-RCCHPNVLPVLGFCAARQFHSFIYPYMANG 292
Query: 249 SLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP 308
SL+ RL+ + G+ PL W QR I G+ +++LH G +IH ++K +N+LLDQ L P
Sbjct: 293 SLQDRLQGQGGSDPLPWPQRVSICSGLLCAVEYLH---GLEIIHSNVKSSNVLLDQNLTP 349
Query: 309 KI 310
K+
Sbjct: 350 KL 351
Score = 51.6 bits (118), Expect = 4e-06
Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 2 YIYELPPEINKELCRLLDNFDYWEELA-GNYMMYTAMDVIEIKEKARHQGISPTEYLLEC 60
YIY+LP + +LCR +D W+ + +Y++ + +IK R QG+S T LL
Sbjct: 4 YIYQLPSWVLDDLCRNMDALSEWDWMEFASYVITDLTQLRKIKSMERVQGVSITRELLWW 63
Query: 61 WGQKNHRIEELFVLLYRMK 79
WG + +++L LL R++
Sbjct: 64 WGMRQATVQQLVDLLCRLE 82
>AF026273-1|AAB87669.1| 590|Homo sapiens interleukin-1
receptor-associated kinase-2 protein.
Length = 590
Score = 88.2 bits (209), Expect = 4e-17
Identities = 55/182 (30%), Positives = 92/182 (50%), Gaps = 11/182 (6%)
Query: 136 DQDTSSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLG 195
D S K +++L S ++ ATDD+++ + +G F VY+G
Sbjct: 174 DSKDFSTSIPKQEKLLSLAGDSLFWSEADVVQATDDFNQNRKISQGTFADVYRGHRHGKP 233
Query: 196 VAVKRLRD----NEGRDQELVR---EMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGG 248
K+LR+ + G + + ++CL + H N+LP+ G+ +Y MA G
Sbjct: 234 FVFKKLRETACSSPGSIERFFQAELQICL-RCCHPNVLPVLGFCAARQFHSFIYPYMANG 292
Query: 249 SLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP 308
SL+ RL+ + G+ PL W QR I G+ +++LH G +IH ++K +N+LLDQ L P
Sbjct: 293 SLQDRLQGQGGSDPLPWPQRVSICSGLLCAVEYLH---GLEIIHSNVKSSNVLLDQNLTP 349
Query: 309 KI 310
K+
Sbjct: 350 KL 351
Score = 51.6 bits (118), Expect = 4e-06
Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 2 YIYELPPEINKELCRLLDNFDYWEELA-GNYMMYTAMDVIEIKEKARHQGISPTEYLLEC 60
YIY+LP + +LCR +D W+ + +Y++ + +IK R QG+S T LL
Sbjct: 4 YIYQLPSWVLDDLCRNMDALSEWDWMEFASYVITDLTQLRKIKSMERVQGVSITRELLWW 63
Query: 61 WGQKNHRIEELFVLLYRMK 79
WG + +++L LL R++
Sbjct: 64 WGMRQATVQQLVDLLCRLE 82
>DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AL121964-4|CAI19612.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AL121964-3|CAI19611.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kinase
splice variant d protein.
Length = 491
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kinase
1c protein.
Length = 518
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kinase
1b protein.
Length = 606
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kinase
1a protein.
Length = 579
Score = 82.6 bits (195), Expect = 2e-15
Identities = 62/181 (34%), Positives = 91/181 (50%), Gaps = 13/181 (7%)
Query: 140 SSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVK 199
SS+ E++ S + +++EE+ + E ++GRG FG V K +W+ VA+K
Sbjct: 8 SSSSSSSAGEMIEAPSQV--LNFEEIDYKEIEVEE--VVGRGAFGVVCKAKWRAKDVAIK 63
Query: 200 RLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDG 259
++ R +V L++ H NI+ LYG L CLV + GGSL L G
Sbjct: 64 QIESESERKAFIVELRQLSRVNHPNIVKLYGACLN--PVCLVMEYAEGGSLYNVLH---G 118
Query: 260 AAPLSWAQRCRIM--C-GVARGLQFLHTMTGSALIHGDIKPANILL-DQCLEPKIGDFGL 315
A PL + M C ++G+ +LH+M ALIH D+KP N+LL KI DFG
Sbjct: 119 AEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGT 178
Query: 316 A 316
A
Sbjct: 179 A 179
>AY283670-1|AAP57089.1| 292|Homo sapiens interleukin-1 receptor
associated kinase 4 mutant form 1 protein.
Length = 292
Score = 81.0 bits (191), Expect = 6e-15
Identities = 77/235 (32%), Positives = 108/235 (45%), Gaps = 19/235 (8%)
Query: 50 GISPTEYLLECWGQKNHRIEELFVLLYRMKHI-PAMRRLTGVVHERFHRLLHKLEAGNGQ 108
G SPT LL WG N +L LL + + PA L V + + L K EA Q
Sbjct: 63 GKSPTSELLFDWGTTNCTAGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQ 121
Query: 109 DGNNARTGGAQRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLA 168
+ T + L D+SS + +K E+ + S+ EL+
Sbjct: 122 QKQMPFCDKDRTLMTPVQN--LEQSYMPPDSSSPE-NKSLEV--SDTRFHSFSFYELKNV 176
Query: 169 TDDWSER------NLLGRGGFGQVYKGEWKLLGVAVKRLR-----DNEGRDQELVREM-C 216
T+++ ER N +G GGFG VYKG VAVK+L E Q+ +E+
Sbjct: 177 TNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKV 236
Query: 217 LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRI 271
+ + +H+N++ L G+S G + CLVY M GSL RL DG PLSW RC+I
Sbjct: 237 MAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKI 291
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 78.6 bits (185), Expect = 3e-14
Identities = 62/149 (41%), Positives = 82/149 (55%), Gaps = 19/149 (12%)
Query: 178 LGRGGFGQVYKGE---WKLLGVAVK---RLRDNEGRDQELVRE---MCLNQYRHDNILPL 228
+G GGFGQVYK WK +A+K L ++ EL+ E M + ++R+ ILP+
Sbjct: 28 VGSGGFGQVYKVRHVHWKTW-LAIKCSPSLHVDDRERMELLEEAKKMEMAKFRY--ILPV 84
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
YG + LV + M GSLE+ L + PL W R RI+ A G+ FLH M
Sbjct: 85 YG--ICREPVGLVMEYMETGSLEKLL----ASEPLPWDLRFRIIHETAVGMNFLHCMA-P 137
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
L+H D+KPANILLD KI DFGLA+
Sbjct: 138 PLLHLDLKPANILLDAHYHVKISDFGLAK 166
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 78.6 bits (185), Expect = 3e-14
Identities = 62/149 (41%), Positives = 82/149 (55%), Gaps = 19/149 (12%)
Query: 178 LGRGGFGQVYKGE---WKLLGVAVK---RLRDNEGRDQELVRE---MCLNQYRHDNILPL 228
+G GGFGQVYK WK +A+K L ++ EL+ E M + ++R+ ILP+
Sbjct: 28 VGSGGFGQVYKVRHVHWKTW-LAIKCSPSLHVDDRERMELLEEAKKMEMAKFRY--ILPV 84
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
YG + LV + M GSLE+ L + PL W R RI+ A G+ FLH M
Sbjct: 85 YG--ICREPVGLVMEYMETGSLEKLL----ASEPLPWDLRFRIIHETAVGMNFLHCMA-P 137
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
L+H D+KPANILLD KI DFGLA+
Sbjct: 138 PLLHLDLKPANILLDAHYHVKISDFGLAK 166
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 78.6 bits (185), Expect = 3e-14
Identities = 62/149 (41%), Positives = 82/149 (55%), Gaps = 19/149 (12%)
Query: 178 LGRGGFGQVYKGE---WKLLGVAVK---RLRDNEGRDQELVRE---MCLNQYRHDNILPL 228
+G GGFGQVYK WK +A+K L ++ EL+ E M + ++R+ ILP+
Sbjct: 28 VGSGGFGQVYKVRHVHWKTW-LAIKCSPSLHVDDRERMELLEEAKKMEMAKFRY--ILPV 84
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
YG + LV + M GSLE+ L + PL W R RI+ A G+ FLH M
Sbjct: 85 YG--ICREPVGLVMEYMETGSLEKLL----ASEPLPWDLRFRIIHETAVGMNFLHCMA-P 137
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
L+H D+KPANILLD KI DFGLA+
Sbjct: 138 PLLHLDLKPANILLDAHYHVKISDFGLAK 166
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 78.6 bits (185), Expect = 3e-14
Identities = 62/149 (41%), Positives = 82/149 (55%), Gaps = 19/149 (12%)
Query: 178 LGRGGFGQVYKGE---WKLLGVAVK---RLRDNEGRDQELVRE---MCLNQYRHDNILPL 228
+G GGFGQVYK WK +A+K L ++ EL+ E M + ++R+ ILP+
Sbjct: 28 VGSGGFGQVYKVRHVHWKTW-LAIKCSPSLHVDDRERMELLEEAKKMEMAKFRY--ILPV 84
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
YG + LV + M GSLE+ L + PL W R RI+ A G+ FLH M
Sbjct: 85 YG--ICREPVGLVMEYMETGSLEKLL----ASEPLPWDLRFRIIHETAVGMNFLHCMA-P 137
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
L+H D+KPANILLD KI DFGLA+
Sbjct: 138 PLLHLDLKPANILLDAHYHVKISDFGLAK 166
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 78.6 bits (185), Expect = 3e-14
Identities = 62/149 (41%), Positives = 82/149 (55%), Gaps = 19/149 (12%)
Query: 178 LGRGGFGQVYKGE---WKLLGVAVK---RLRDNEGRDQELVRE---MCLNQYRHDNILPL 228
+G GGFGQVYK WK +A+K L ++ EL+ E M + ++R+ ILP+
Sbjct: 28 VGSGGFGQVYKVRHVHWKTW-LAIKCSPSLHVDDRERMELLEEAKKMEMAKFRY--ILPV 84
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
YG + LV + M GSLE+ L + PL W R RI+ A G+ FLH M
Sbjct: 85 YG--ICREPVGLVMEYMETGSLEKLL----ASEPLPWDLRFRIIHETAVGMNFLHCMA-P 137
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
L+H D+KPANILLD KI DFGLA+
Sbjct: 138 PLLHLDLKPANILLDAHYHVKISDFGLAK 166
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 78.6 bits (185), Expect = 3e-14
Identities = 62/149 (41%), Positives = 82/149 (55%), Gaps = 19/149 (12%)
Query: 178 LGRGGFGQVYKGE---WKLLGVAVK---RLRDNEGRDQELVRE---MCLNQYRHDNILPL 228
+G GGFGQVYK WK +A+K L ++ EL+ E M + ++R+ ILP+
Sbjct: 28 VGSGGFGQVYKVRHVHWKTW-LAIKCSPSLHVDDRERMELLEEAKKMEMAKFRY--ILPV 84
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
YG + LV + M GSLE+ L + PL W R RI+ A G+ FLH M
Sbjct: 85 YG--ICREPVGLVMEYMETGSLEKLL----ASEPLPWDLRFRIIHETAVGMNFLHCMA-P 137
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
L+H D+KPANILLD KI DFGLA+
Sbjct: 138 PLLHLDLKPANILLDAHYHVKISDFGLAK 166
>U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein
kinase protein.
Length = 847
Score = 77.8 bits (183), Expect = 6e-14
Identities = 62/174 (35%), Positives = 85/174 (48%), Gaps = 29/174 (16%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQY 220
S++ELRL ++G GGFG+VY+G W+ VAVK R + D + E +
Sbjct: 113 SFQELRL-------EEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEA 165
Query: 221 R------HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRL--RPKDGAAPLSWAQRCRIM 272
R H NI+ L L P CLV + AGG L + L R ++WA +
Sbjct: 166 RLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQ---- 221
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K NILL Q +E KI DFGLAR+
Sbjct: 222 --IARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLARE 273
>L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein.
Length = 847
Score = 77.8 bits (183), Expect = 6e-14
Identities = 62/174 (35%), Positives = 85/174 (48%), Gaps = 29/174 (16%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQY 220
S++ELRL ++G GGFG+VY+G W+ VAVK R + D + E +
Sbjct: 113 SFQELRL-------EEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEA 165
Query: 221 R------HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRL--RPKDGAAPLSWAQRCRIM 272
R H NI+ L L P CLV + AGG L + L R ++WA +
Sbjct: 166 RLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQ---- 221
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K NILL Q +E KI DFGLAR+
Sbjct: 222 --IARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLARE 273
>BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 77.8 bits (183), Expect = 6e-14
Identities = 62/174 (35%), Positives = 85/174 (48%), Gaps = 29/174 (16%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQY 220
S++ELRL ++G GGFG+VY+G W+ VAVK R + D + E +
Sbjct: 113 SFQELRL-------EEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEA 165
Query: 221 R------HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRL--RPKDGAAPLSWAQRCRIM 272
R H NI+ L L P CLV + AGG L + L R ++WA +
Sbjct: 166 RLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQ---- 221
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K NILL Q +E KI DFGLAR+
Sbjct: 222 --IARGMHYLHCEALVPVIHRDLKSNNILLLQHIESDDMEHKTLKITDFGLARE 273
>BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 77.8 bits (183), Expect = 6e-14
Identities = 62/174 (35%), Positives = 85/174 (48%), Gaps = 29/174 (16%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQY 220
S++ELRL ++G GGFG+VY+G W+ VAVK R + D + E +
Sbjct: 113 SFQELRL-------EEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEA 165
Query: 221 R------HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRL--RPKDGAAPLSWAQRCRIM 272
R H NI+ L L P CLV + AGG L + L R ++WA +
Sbjct: 166 RLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQ---- 221
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K NILL Q +E KI DFGLAR+
Sbjct: 222 --IARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLARE 273
>AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 847
Score = 77.8 bits (183), Expect = 6e-14
Identities = 62/174 (35%), Positives = 85/174 (48%), Gaps = 29/174 (16%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQY 220
S++ELRL ++G GGFG+VY+G W+ VAVK R + D + E +
Sbjct: 113 SFQELRL-------EEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEA 165
Query: 221 R------HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRL--RPKDGAAPLSWAQRCRIM 272
R H NI+ L L P CLV + AGG L + L R ++WA +
Sbjct: 166 RLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQ---- 221
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K NILL Q +E KI DFGLAR+
Sbjct: 222 --IARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLARE 273
>Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase with
SH3 domain, leucine zipper domain and proline rich
protein.
Length = 953
Score = 75.4 bits (177), Expect = 3e-13
Identities = 55/158 (34%), Positives = 79/158 (50%), Gaps = 22/158 (13%)
Query: 177 LLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYR------HDNILPLYG 230
++G GGFG+VY+ W+ VAVK R + +D + E + R H NI+ L G
Sbjct: 103 IIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRG 162
Query: 231 YSLGGPEACLVYQLMAGGSLEQRL--RPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
L P CLV + GG+L + L R ++WA + VARG+ +LH
Sbjct: 163 ACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQ------VARGMNYLHNDAPV 216
Query: 289 ALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+IH D+K NIL+ + +E KI DFGLAR+
Sbjct: 217 PIIHRDLKSINILILEAIENHNLADTVLKITDFGLARE 254
>X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2
protein.
Length = 954
Score = 75.4 bits (177), Expect = 3e-13
Identities = 55/158 (34%), Positives = 79/158 (50%), Gaps = 22/158 (13%)
Query: 177 LLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYR------HDNILPLYG 230
++G GGFG+VY+ W+ VAVK R + +D + E + R H NI+ L G
Sbjct: 103 IIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRG 162
Query: 231 YSLGGPEACLVYQLMAGGSLEQRL--RPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
L P CLV + GG+L + L R ++WA + VARG+ +LH
Sbjct: 163 ACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQ------VARGMNYLHNDAPV 216
Query: 289 ALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+IH D+K NIL+ + +E KI DFGLAR+
Sbjct: 217 PIIHRDLKSINILILEAIENHNLADTVLKITDFGLARE 254
>X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein.
Length = 451
Score = 75.4 bits (177), Expect = 3e-13
Identities = 57/169 (33%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 152 RKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWK-LLGVAVKRL-RDNEGRDQ 209
RK P +++ ++++ LG G FG+V++G WK + VA+K + RDN Q
Sbjct: 171 RKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQ 230
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
L E+ + + RH +IL LY G ++ +LMA GSL + LR D L ++
Sbjct: 231 MLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKV-LPVSEL 289
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
I VA G+ +L + IH D+ NIL+ + K+GDFGLAR
Sbjct: 290 LDIAWQVAEGMCYLESQN---YIHRDLAARNILVGENTLCKVGDFGLAR 335
>U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein
tyrosine kinase protein.
Length = 451
Score = 75.4 bits (177), Expect = 3e-13
Identities = 57/169 (33%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 152 RKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWK-LLGVAVKRL-RDNEGRDQ 209
RK P +++ ++++ LG G FG+V++G WK + VA+K + RDN Q
Sbjct: 171 RKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQ 230
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
L E+ + + RH +IL LY G ++ +LMA GSL + LR D L ++
Sbjct: 231 MLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKV-LPVSEL 289
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
I VA G+ +L + IH D+ NIL+ + K+GDFGLAR
Sbjct: 290 LDIAWQVAEGMCYLESQN---YIHRDLAARNILVGENTLCKVGDFGLAR 335
>BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine
kinase 6 protein.
Length = 451
Score = 75.4 bits (177), Expect = 3e-13
Identities = 57/169 (33%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 152 RKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWK-LLGVAVKRL-RDNEGRDQ 209
RK P +++ ++++ LG G FG+V++G WK + VA+K + RDN Q
Sbjct: 171 RKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQ 230
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
L E+ + + RH +IL LY G ++ +LMA GSL + LR D L ++
Sbjct: 231 MLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKV-LPVSEL 289
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
I VA G+ +L + IH D+ NIL+ + K+GDFGLAR
Sbjct: 290 LDIAWQVAEGMCYLESQN---YIHRDLAARNILVGENTLCKVGDFGLAR 335
>AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein.
Length = 451
Score = 75.4 bits (177), Expect = 3e-13
Identities = 57/169 (33%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 152 RKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWK-LLGVAVKRL-RDNEGRDQ 209
RK P +++ ++++ LG G FG+V++G WK + VA+K + RDN Q
Sbjct: 171 RKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQ 230
Query: 210 ELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQR 268
L E+ + + RH +IL LY G ++ +LMA GSL + LR D L ++
Sbjct: 231 MLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKV-LPVSEL 289
Query: 269 CRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
I VA G+ +L + IH D+ NIL+ + K+GDFGLAR
Sbjct: 290 LDIAWQVAEGMCYLESQN---YIHRDLAARNILVGENTLCKVGDFGLAR 335
>AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 1036
Score = 74.1 bits (174), Expect = 7e-13
Identities = 63/187 (33%), Positives = 91/187 (48%), Gaps = 27/187 (14%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRD-----QELV 212
P + +A + + L+G GGFGQVY+ W+ VAVK R + +D + +
Sbjct: 110 PSRPSSPVHVAFERLELKELIGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVR 169
Query: 213 REMCL-NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA---QR 268
RE L RH NI+ L G L P CLV + GG+L + L + AAP A +R
Sbjct: 170 REARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAAN-AAPDPRAPGPRR 228
Query: 269 CRIM---------CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIG 311
R + +ARG+ +LH ++H D+K +NILL + +E KI
Sbjct: 229 ARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKIT 288
Query: 312 DFGLARK 318
DFGLAR+
Sbjct: 289 DFGLARE 295
>AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 570
Score = 74.1 bits (174), Expect = 7e-13
Identities = 63/187 (33%), Positives = 91/187 (48%), Gaps = 27/187 (14%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRD-----QELV 212
P + +A + + L+G GGFGQVY+ W+ VAVK R + +D + +
Sbjct: 110 PSRPSSPVHVAFERLELKELIGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVR 169
Query: 213 REMCL-NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA---QR 268
RE L RH NI+ L G L P CLV + GG+L + L + AAP A +R
Sbjct: 170 REARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAAN-AAPDPRAPGPRR 228
Query: 269 CRIM---------CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIG 311
R + +ARG+ +LH ++H D+K +NILL + +E KI
Sbjct: 229 ARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKIT 288
Query: 312 DFGLARK 318
DFGLAR+
Sbjct: 289 DFGLARE 295
>AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4beta
protein.
Length = 1036
Score = 74.1 bits (174), Expect = 7e-13
Identities = 64/187 (34%), Positives = 91/187 (48%), Gaps = 27/187 (14%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRD-----QELV 212
P + +A + + L+G GGFGQVY+ W+ VAVK R + +D + +
Sbjct: 110 PSRPSSPVHVAFERLELKELIGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVR 169
Query: 213 REMCL-NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA---QR 268
RE L RH NI+ L G L P CLV + GG+L + L + AAP A +R
Sbjct: 170 REARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAAN-AAPDPRAPGPRR 228
Query: 269 CRIM---------CGVARGLQFLHTMTGSALIHGDIKPANILL-------DQCLEP-KIG 311
R + +ARG+ +LH ++H D+K +NILL D C + KI
Sbjct: 229 ARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNKTLKIT 288
Query: 312 DFGLARK 318
DFGLAR+
Sbjct: 289 DFGLARE 295
>AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase
4alpha protein.
Length = 570
Score = 74.1 bits (174), Expect = 7e-13
Identities = 64/187 (34%), Positives = 91/187 (48%), Gaps = 27/187 (14%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRD-----QELV 212
P + +A + + L+G GGFGQVY+ W+ VAVK R + +D + +
Sbjct: 110 PSRPSSPVHVAFERLELKELIGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVR 169
Query: 213 REMCL-NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA---QR 268
RE L RH NI+ L G L P CLV + GG+L + L + AAP A +R
Sbjct: 170 REARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAAN-AAPDPRAPGPRR 228
Query: 269 CRIM---------CGVARGLQFLHTMTGSALIHGDIKPANILL-------DQCLEP-KIG 311
R + +ARG+ +LH ++H D+K +NILL D C + KI
Sbjct: 229 ARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNKTLKIT 288
Query: 312 DFGLARK 318
DFGLAR+
Sbjct: 289 DFGLARE 295
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA
sequence from clone RP4-697K14 on chromosome 20. ).
Length = 488
Score = 73.3 bits (172), Expect = 1e-12
Identities = 47/142 (33%), Positives = 74/142 (52%), Gaps = 6/142 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYSLGG 235
LG G FG+V++G W L VA+K ++ + +L +E+ L RH+ ++ L+ GG
Sbjct: 236 LGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGG 295
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
+V +LM G+L+ L +G A L C VA G+ +L ++H D+
Sbjct: 296 EPVYIVTELMRKGNLQAFLGTPEGRA-LRLPPLLGFACQVAEGMSYLEEQR---VVHRDL 351
Query: 296 KPANILLDQCLEPKIGDFGLAR 317
N+L+D L K+ DFGLAR
Sbjct: 352 AARNVLVDDGLACKVADFGLAR 373
>M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1
mRNA. ).
Length = 543
Score = 72.1 bits (169), Expect = 3e-12
Identities = 55/166 (33%), Positives = 85/166 (51%), Gaps = 8/166 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG+G FG+V+ G W VA+K L+ + ++E + + RHD ++PLY
Sbjct: 283 LGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEE 342
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + M+ GSL L+ DG L Q + +A G+ ++ M IH D+
Sbjct: 343 P-IYIVTEFMSKGSLLDFLKEGDGKY-LKLPQLVDMAAQIADGMAYIERMN---YIHRDL 397
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
+ ANIL+ + L KI DFGLAR +E T + ++FP + A E
Sbjct: 398 RAANILVGENLVCKIADFGLARL-IEDNEYTARQGAKFPIKWTAPE 442
>D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein.
Length = 626
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 11/156 (7%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLLG-VAVKRLRDNEGRDQELVREMCL-NQYRHDNILP 227
DD+ +G G F +VYK + G V V ++ +RE+ L N+ RH NIL
Sbjct: 55 DDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILR 114
Query: 228 LYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTG 287
G + + + + M GG+LEQ L + PLSW R + +ARGL++LH+
Sbjct: 115 FMGVCVHQGQLHALTEYMNGGTLEQLLSSPE---PLSWPVRLHLALDIARGLRYLHS--- 168
Query: 288 SALIHGDIKPANILL---DQCLEPKIGDFGLARKGP 320
+ H D+ N L+ D+ +GDFGLA K P
Sbjct: 169 KGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIP 204
>BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 11/156 (7%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLLG-VAVKRLRDNEGRDQELVREMCL-NQYRHDNILP 227
DD+ +G G F +VYK + G V V ++ +RE+ L N+ RH NIL
Sbjct: 55 DDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILR 114
Query: 228 LYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTG 287
G + + + + M GG+LEQ L + PLSW R + +ARGL++LH+
Sbjct: 115 FMGVCVHQGQLHALTEYMNGGTLEQLLSSPE---PLSWPVRLHLALDIARGLRYLHS--- 168
Query: 288 SALIHGDIKPANILL---DQCLEPKIGDFGLARKGP 320
+ H D+ N L+ D+ +GDFGLA K P
Sbjct: 169 KGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIP 204
>BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral oncogene homolog 1 protein.
Length = 543
Score = 72.1 bits (169), Expect = 3e-12
Identities = 55/166 (33%), Positives = 85/166 (51%), Gaps = 8/166 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG+G FG+V+ G W VA+K L+ + ++E + + RHD ++PLY
Sbjct: 283 LGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEE 342
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + M+ GSL L+ DG L Q + +A G+ ++ M IH D+
Sbjct: 343 P-IYIVTEFMSKGSLLDFLKEGDGKY-LKLPQLVDMAAQIADGMAYIERMN---YIHRDL 397
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
+ ANIL+ + L KI DFGLAR +E T + ++FP + A E
Sbjct: 398 RAANILVGENLVCKIADFGLARL-IEDNEYTARQGAKFPIKWTAPE 442
>BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 11/156 (7%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLLG-VAVKRLRDNEGRDQELVREMCL-NQYRHDNILP 227
DD+ +G G F +VYK + G V V ++ +RE+ L N+ RH NIL
Sbjct: 55 DDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILR 114
Query: 228 LYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTG 287
G + + + + M GG+LEQ L + PLSW R + +ARGL++LH+
Sbjct: 115 FMGVCVHQGQLHALTEYMNGGTLEQLLSSPE---PLSWPVRLHLALDIARGLRYLHS--- 168
Query: 288 SALIHGDIKPANILL---DQCLEPKIGDFGLARKGP 320
+ H D+ N L+ D+ +GDFGLA K P
Sbjct: 169 KGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIP 204
>BC004553-1|AAH04553.1| 540|Homo sapiens receptor-interacting
serine-threonine kinase 2 protein.
Length = 540
Score = 72.1 bits (169), Expect = 3e-12
Identities = 56/171 (32%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Query: 155 SAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKG---EWKLLGVAVKRLRDN----EGR 207
SA+P + Y +L ++ L RG G V +W++ VAVK L + +
Sbjct: 8 SALPTIPYHKL-------ADLRYLSRGASGTVSSARHADWRVQ-VAVKHLHIHTPLLDSE 59
Query: 208 DQELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA 266
++++RE L++ R ILP+ G +V + M GSL + L K ++W
Sbjct: 60 RKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWP 119
Query: 267 QRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R RI+ +A G+ +LH MT L+H D+K NILLD KI DFGL++
Sbjct: 120 LRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169
>AY358814-1|AAQ89173.1| 540|Homo sapiens RIPK2 protein.
Length = 540
Score = 72.1 bits (169), Expect = 3e-12
Identities = 56/171 (32%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Query: 155 SAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKG---EWKLLGVAVKRLRDN----EGR 207
SA+P + Y +L ++ L RG G V +W++ VAVK L + +
Sbjct: 8 SALPTIPYHKL-------ADLRYLSRGASGTVSSARHADWRVQ-VAVKHLHIHTPLLDSE 59
Query: 208 DQELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA 266
++++RE L++ R ILP+ G +V + M GSL + L K ++W
Sbjct: 60 RKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWP 119
Query: 267 QRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R RI+ +A G+ +LH MT L+H D+K NILLD KI DFGL++
Sbjct: 120 LRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169
>AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase 1
protein.
Length = 626
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 11/156 (7%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLLG-VAVKRLRDNEGRDQELVREMCL-NQYRHDNILP 227
DD+ +G G F +VYK + G V V ++ +RE+ L N+ RH NIL
Sbjct: 55 DDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILR 114
Query: 228 LYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTG 287
G + + + + M GG+LEQ L + PLSW R + +ARGL++LH+
Sbjct: 115 FMGVCVHQGQLHALTEYMNGGTLEQLLSSPE---PLSWPVRLHLALDIARGLRYLHS--- 168
Query: 288 SALIHGDIKPANILL---DQCLEPKIGDFGLARKGP 320
+ H D+ N L+ D+ +GDFGLA K P
Sbjct: 169 KGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIP 204
>AF078530-1|AAC27722.1| 540|Homo sapiens receptor interacting
protein 2 protein.
Length = 540
Score = 72.1 bits (169), Expect = 3e-12
Identities = 56/171 (32%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Query: 155 SAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKG---EWKLLGVAVKRLRDN----EGR 207
SA+P + Y +L ++ L RG G V +W++ VAVK L + +
Sbjct: 8 SALPTIPYHKL-------ADLRYLSRGASGTVSSARHADWRVQ-VAVKHLHIHTPLLDSE 59
Query: 208 DQELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA 266
++++RE L++ R ILP+ G +V + M GSL + L K ++W
Sbjct: 60 RKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWP 119
Query: 267 QRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R RI+ +A G+ +LH MT L+H D+K NILLD KI DFGL++
Sbjct: 120 LRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169
>AF064824-1|AAC25668.1| 540|Homo sapiens CARD-containing ICE
associated kinase protein.
Length = 540
Score = 72.1 bits (169), Expect = 3e-12
Identities = 56/171 (32%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Query: 155 SAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKG---EWKLLGVAVKRLRDN----EGR 207
SA+P + Y +L ++ L RG G V +W++ VAVK L + +
Sbjct: 8 SALPTIPYHKL-------ADLRYLSRGASGTVSSARHADWRVQ-VAVKHLHIHTPLLDSE 59
Query: 208 DQELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA 266
++++RE L++ R ILP+ G +V + M GSL + L K ++W
Sbjct: 60 RKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWP 119
Query: 267 QRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R RI+ +A G+ +LH MT L+H D+K NILLD KI DFGL++
Sbjct: 120 LRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169
>AF027706-1|AAC34970.1| 540|Homo sapiens serine/threonine kinase
RICK protein.
Length = 540
Score = 72.1 bits (169), Expect = 3e-12
Identities = 56/171 (32%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Query: 155 SAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKG---EWKLLGVAVKRLRDN----EGR 207
SA+P + Y +L ++ L RG G V +W++ VAVK L + +
Sbjct: 8 SALPTIPYHKL-------ADLRYLSRGASGTVSSARHADWRVQ-VAVKHLHIHTPLLDSE 59
Query: 208 DQELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA 266
++++RE L++ R ILP+ G +V + M GSL + L K ++W
Sbjct: 60 RKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWP 119
Query: 267 QRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R RI+ +A G+ +LH MT L+H D+K NILLD KI DFGL++
Sbjct: 120 LRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169
>AC004003-1|AAC24561.1| 540|Homo sapiens WUGSC:H_RG437L15.1
protein.
Length = 540
Score = 72.1 bits (169), Expect = 3e-12
Identities = 56/171 (32%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Query: 155 SAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKG---EWKLLGVAVKRLRDN----EGR 207
SA+P + Y +L ++ L RG G V +W++ VAVK L + +
Sbjct: 8 SALPTIPYHKL-------ADLRYLSRGASGTVSSARHADWRVQ-VAVKHLHIHTPLLDSE 59
Query: 208 DQELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA 266
++++RE L++ R ILP+ G +V + M GSL + L K ++W
Sbjct: 60 RKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWP 119
Query: 267 QRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R RI+ +A G+ +LH MT L+H D+K NILLD KI DFGL++
Sbjct: 120 LRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 71.7 bits (168), Expect = 4e-12
Identities = 49/149 (32%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+VYKG KL G VA+K L+ Q L + Q+ H NI+ L
Sbjct: 624 VIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 683
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 684 EGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTV--IQLVGMLRGIAAGMKYLAEMN-- 739
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NILL+ L K+ DFGL+R
Sbjct: 740 -YVHRDLAARNILLNSNLVCKVSDFGLSR 767
>BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein.
Length = 1104
Score = 71.3 bits (167), Expect = 5e-12
Identities = 61/176 (34%), Positives = 86/176 (48%), Gaps = 25/176 (14%)
Query: 162 YEELRLATDDWSERNL---LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQ----ELVRE 214
Y ++L D++E L +G GGFG+VY+ W VAVK R + D E VR+
Sbjct: 131 YPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQ 190
Query: 215 MC--LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPL--SWAQRCR 270
+H NI+ L G L P CLV + GG L + L K + +WA +
Sbjct: 191 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQ-- 248
Query: 271 IMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K +NIL+ Q +E KI DFGLAR+
Sbjct: 249 ----IARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLARE 300
>BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein.
Length = 1103
Score = 71.3 bits (167), Expect = 5e-12
Identities = 61/176 (34%), Positives = 86/176 (48%), Gaps = 25/176 (14%)
Query: 162 YEELRLATDDWSERNL---LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQ----ELVRE 214
Y ++L D++E L +G GGFG+VY+ W VAVK R + D E VR+
Sbjct: 130 YPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQ 189
Query: 215 MC--LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPL--SWAQRCR 270
+H NI+ L G L P CLV + GG L + L K + +WA +
Sbjct: 190 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQ-- 247
Query: 271 IMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K +NIL+ Q +E KI DFGLAR+
Sbjct: 248 ----IARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLARE 299
>AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein
kinase 1 protein.
Length = 1104
Score = 71.3 bits (167), Expect = 5e-12
Identities = 61/176 (34%), Positives = 86/176 (48%), Gaps = 25/176 (14%)
Query: 162 YEELRLATDDWSERNL---LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQ----ELVRE 214
Y ++L D++E L +G GGFG+VY+ W VAVK R + D E VR+
Sbjct: 131 YPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQ 190
Query: 215 MC--LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPL--SWAQRCR 270
+H NI+ L G L P CLV + GG L + L K + +WA +
Sbjct: 191 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQ-- 248
Query: 271 IMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K +NIL+ Q +E KI DFGLAR+
Sbjct: 249 ----IARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLARE 300
>AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase MLK1
protein.
Length = 1066
Score = 71.3 bits (167), Expect = 5e-12
Identities = 61/176 (34%), Positives = 86/176 (48%), Gaps = 25/176 (14%)
Query: 162 YEELRLATDDWSERNL---LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQ----ELVRE 214
Y ++L D++E L +G GGFG+VY+ W VAVK R + D E VR+
Sbjct: 79 YPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQ 138
Query: 215 MC--LNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPL--SWAQRCR 270
+H NI+ L G L P CLV + GG L + L K + +WA +
Sbjct: 139 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQ-- 196
Query: 271 IMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEP--------KIGDFGLARK 318
+ARG+ +LH +IH D+K +NIL+ Q +E KI DFGLAR+
Sbjct: 197 ----IARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLARE 248
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 70.9 bits (166), Expect = 6e-12
Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 15/154 (9%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLL--GVAVKRLRDNEGRD--QELVREMCLNQY-RHDN 224
+DW LG G +G+V ++ VAVK + D + + +E+C+N+ H+N
Sbjct: 7 EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHEN 66
Query: 225 ILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC--RIMCGVARGLQFL 282
++ YG+ G L + +GG L R+ P G P AQR ++M GV +L
Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGM-PEPDAQRFFHQLMAGVV----YL 121
Query: 283 HTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
H G + H DIKP N+LLD+ KI DFGLA
Sbjct: 122 H---GIGITHRDIKPENLLLDERDNLKISDFGLA 152
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 70.9 bits (166), Expect = 6e-12
Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 15/154 (9%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLL--GVAVKRLRDNEGRD--QELVREMCLNQY-RHDN 224
+DW LG G +G+V ++ VAVK + D + + +E+C+N+ H+N
Sbjct: 7 EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHEN 66
Query: 225 ILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC--RIMCGVARGLQFL 282
++ YG+ G L + +GG L R+ P G P AQR ++M GV +L
Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGM-PEPDAQRFFHQLMAGVV----YL 121
Query: 283 HTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
H G + H DIKP N+LLD+ KI DFGLA
Sbjct: 122 H---GIGITHRDIKPENLLLDERDNLKISDFGLA 152
>AY524045-1|AAS94254.1| 540|Homo sapiens GIG30 protein.
Length = 540
Score = 70.9 bits (166), Expect = 6e-12
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 17/171 (9%)
Query: 155 SAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKG---EWKLLGVAVKRLRDNE----GR 207
SA+P + Y +L ++ L RG G V +W++ VAVK L +
Sbjct: 8 SALPTIPYHKL-------ADLRYLSRGASGTVSSARHADWRVQ-VAVKHLHIHTPLLGSE 59
Query: 208 DQELVREM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWA 266
++++RE L++ R ILP+ G +V + M GSL + L K ++W
Sbjct: 60 RKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWP 119
Query: 267 QRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
R RI+ +A G+ +LH MT L+H D+K NILLD KI DFGL++
Sbjct: 120 LRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 70.9 bits (166), Expect = 6e-12
Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 15/154 (9%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLL--GVAVKRLRDNEGRD--QELVREMCLNQY-RHDN 224
+DW LG G +G+V ++ VAVK + D + + +E+C+N+ H+N
Sbjct: 7 EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHEN 66
Query: 225 ILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC--RIMCGVARGLQFL 282
++ YG+ G L + +GG L R+ P G P AQR ++M GV +L
Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGM-PEPDAQRFFHQLMAGVV----YL 121
Query: 283 HTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
H G + H DIKP N+LLD+ KI DFGLA
Sbjct: 122 H---GIGITHRDIKPENLLLDERDNLKISDFGLA 152
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 70.9 bits (166), Expect = 6e-12
Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 15/154 (9%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLL--GVAVKRLRDNEGRD--QELVREMCLNQY-RHDN 224
+DW LG G +G+V ++ VAVK + D + + +E+C+N+ H+N
Sbjct: 7 EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHEN 66
Query: 225 ILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC--RIMCGVARGLQFL 282
++ YG+ G L + +GG L R+ P G P AQR ++M GV +L
Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGM-PEPDAQRFFHQLMAGVV----YL 121
Query: 283 HTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
H G + H DIKP N+LLD+ KI DFGLA
Sbjct: 122 H---GIGITHRDIKPENLLLDERDNLKISDFGLA 152
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 70.9 bits (166), Expect = 6e-12
Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 15/154 (9%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLL--GVAVKRLRDNEGRD--QELVREMCLNQY-RHDN 224
+DW LG G +G+V ++ VAVK + D + + +E+C+N+ H+N
Sbjct: 7 EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHEN 66
Query: 225 ILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC--RIMCGVARGLQFL 282
++ YG+ G L + +GG L R+ P G P AQR ++M GV +L
Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGM-PEPDAQRFFHQLMAGVV----YL 121
Query: 283 HTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
H G + H DIKP N+LLD+ KI DFGLA
Sbjct: 122 H---GIGITHRDIKPENLLLDERDNLKISDFGLA 152
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 70.9 bits (166), Expect = 6e-12
Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 15/154 (9%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLL--GVAVKRLRDNEGRD--QELVREMCLNQY-RHDN 224
+DW LG G +G+V ++ VAVK + D + + +E+C+N+ H+N
Sbjct: 7 EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHEN 66
Query: 225 ILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC--RIMCGVARGLQFL 282
++ YG+ G L + +GG L R+ P G P AQR ++M GV +L
Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGM-PEPDAQRFFHQLMAGVV----YL 121
Query: 283 HTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
H G + H DIKP N+LLD+ KI DFGLA
Sbjct: 122 H---GIGITHRDIKPENLLLDERDNLKISDFGLA 152
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 70.5 bits (165), Expect = 8e-12
Identities = 48/149 (32%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+VYKG KL G VA+K L+ Q L + Q+ H NI+ L
Sbjct: 624 VIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 683
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 684 EGVVTKSRPVMIITEFMENGALDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLAEMN-- 739
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 740 -YVHRDLAARNILVNSNLVCKVSDFGLSR 767
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 70.5 bits (165), Expect = 8e-12
Identities = 48/149 (32%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+VYKG KL G VA+K L+ Q L + Q+ H NI+ L
Sbjct: 613 VIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 672
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 673 EGVVTKSRPVMIITEFMENGALDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLAEMN-- 728
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 729 -YVHRDLAARNILVNSNLVCKVSDFGLSR 756
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 70.5 bits (165), Expect = 8e-12
Identities = 48/149 (32%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+VYKG KL G VA+K L+ Q L + Q+ H NI+ L
Sbjct: 624 VIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 683
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 684 EGVVTKSRPVMIITEFMENGALDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLAEMN-- 739
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 740 -YVHRDLAARNILVNSNLVCKVSDFGLSR 767
>BC062584-1|AAH62584.1| 518|Homo sapiens receptor-interacting
serine-threonine kinase 3 protein.
Length = 518
Score = 69.3 bits (162), Expect = 2e-11
Identities = 47/155 (30%), Positives = 84/155 (54%), Gaps = 11/155 (7%)
Query: 167 LATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLRDNEGRDQELVREMCL-NQY--R 221
++ ++ + L+G+GGFG V++ + + G VAVK + +++ +E+ L N++ R
Sbjct: 16 VSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVK-IVNSKAISREVKAMASLDNEFVLR 74
Query: 222 HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQF 281
+ ++ + P+ LV + M GSL L+ + P W CR++ V G+ +
Sbjct: 75 LEGVIEKVNWDQD-PKPALVTKFMENGSLSGLLQSQ---CPRPWPLLCRLLKEVVLGMFY 130
Query: 282 LHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
LH L+H D+KP+N+LLD L K+ DFGL+
Sbjct: 131 LHDQN-PVLLHRDLKPSNVLLDPELHVKLADFGLS 164
>AY494983-1|AAS75517.1| 231|Homo sapiens RIP3 gamma protein.
Length = 231
Score = 69.3 bits (162), Expect = 2e-11
Identities = 47/155 (30%), Positives = 84/155 (54%), Gaps = 11/155 (7%)
Query: 167 LATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLRDNEGRDQELVREMCL-NQY--R 221
++ ++ + L+G+GGFG V++ + + G VAVK + +++ +E+ L N++ R
Sbjct: 16 VSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVK-IVNSKAISREVKAMASLDNEFVLR 74
Query: 222 HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQF 281
+ ++ + P+ LV + M GSL L+ + P W CR++ V G+ +
Sbjct: 75 LEGVIEKVNWDQD-PKPALVTKFMENGSLSGLLQSQ---CPRPWPLLCRLLKEVVLGMFY 130
Query: 282 LHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
LH L+H D+KP+N+LLD L K+ DFGL+
Sbjct: 131 LHDQN-PVLLHRDLKPSNVLLDPELHVKLADFGLS 164
>AY494982-1|AAS75516.1| 252|Homo sapiens RIP3 beta protein.
Length = 252
Score = 69.3 bits (162), Expect = 2e-11
Identities = 47/155 (30%), Positives = 84/155 (54%), Gaps = 11/155 (7%)
Query: 167 LATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLRDNEGRDQELVREMCL-NQY--R 221
++ ++ + L+G+GGFG V++ + + G VAVK + +++ +E+ L N++ R
Sbjct: 16 VSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVK-IVNSKAISREVKAMASLDNEFVLR 74
Query: 222 HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQF 281
+ ++ + P+ LV + M GSL L+ + P W CR++ V G+ +
Sbjct: 75 LEGVIEKVNWDQD-PKPALVTKFMENGSLSGLLQSQ---CPRPWPLLCRLLKEVVLGMFY 130
Query: 282 LHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
LH L+H D+KP+N+LLD L K+ DFGL+
Sbjct: 131 LHDQN-PVLLHRDLKPSNVLLDPELHVKLADFGLS 164
>AY453693-1|AAS16359.1| 518|Homo sapiens receptor interacting
protein 3 protein.
Length = 518
Score = 69.3 bits (162), Expect = 2e-11
Identities = 47/155 (30%), Positives = 84/155 (54%), Gaps = 11/155 (7%)
Query: 167 LATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLRDNEGRDQELVREMCL-NQY--R 221
++ ++ + L+G+GGFG V++ + + G VAVK + +++ +E+ L N++ R
Sbjct: 16 VSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVK-IVNSKAISREVKAMASLDNEFVLR 74
Query: 222 HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQF 281
+ ++ + P+ LV + M GSL L+ + P W CR++ V G+ +
Sbjct: 75 LEGVIEKVNWDQD-PKPALVTKFMENGSLSGLLQSQ---CPRPWPLLCRLLKEVVLGMFY 130
Query: 282 LHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
LH L+H D+KP+N+LLD L K+ DFGL+
Sbjct: 131 LHDQN-PVLLHRDLKPSNVLLDPELHVKLADFGLS 164
>AK075275-1|BAC11512.1| 427|Homo sapiens protein ( Homo sapiens
cDNA FLJ90794 fis, clone THYRO1001700, weakly similar to
SERINE/THREONINE PROTEIN KINASE RIP (EC 2.7.1.-). ).
Length = 427
Score = 69.3 bits (162), Expect = 2e-11
Identities = 47/155 (30%), Positives = 84/155 (54%), Gaps = 11/155 (7%)
Query: 167 LATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLRDNEGRDQELVREMCL-NQY--R 221
++ ++ + L+G+GGFG V++ + + G VAVK + +++ +E+ L N++ R
Sbjct: 16 VSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVK-IVNSKAISREVKAMASLDNEFVLR 74
Query: 222 HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQF 281
+ ++ + P+ LV + M GSL L+ + P W CR++ V G+ +
Sbjct: 75 LEGVIEKVNWDQD-PKPALVTKFMENGSLSGLLQSQ---CPRPWPLLCRLLKEVVLGMFY 130
Query: 282 LHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
LH L+H D+KP+N+LLD L K+ DFGL+
Sbjct: 131 LHDQN-PVLLHRDLKPSNVLLDPELHVKLADFGLS 164
>M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein.
Length = 298
Score = 68.9 bits (161), Expect = 3e-11
Identities = 51/143 (35%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEG---RDQELVREM-CLNQYRHDNILPLYGYSL 233
+G G FG V++G W VAVK L+ ++ + Q EM L + RH NILP G+ +
Sbjct: 25 IGTGSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILPFMGF-M 82
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P ++ Q G SL L D Q + A+G+ +LH +IH
Sbjct: 83 TRPGVAIITQWCEGSSLYHHLHVAD--TRFDMVQLIDVARQTAQGMDYLHAKN---IIHR 137
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 138 DLKSNNIFLHEGLTVKIGDFGLA 160
>M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein.
Length = 766
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/143 (37%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELV---REM-CLNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L Q+L E+ L + RH NIL GYS
Sbjct: 463 IGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST 521
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P+ +V Q G SL L + + I A+G+ +LH ++IH
Sbjct: 522 K-PQLAIVTQWCEGSSLYHHLHIIE--TKFEMIKLIDIARQTAQGMDYLHA---KSIIHR 575
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 576 DLKSNNIFLHEDLTVKIGDFGLA 598
>M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein.
Length = 328
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/143 (37%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELV---REM-CLNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L Q+L E+ L + RH NIL GYS
Sbjct: 25 IGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST 83
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P+ +V Q G SL L + + I A+G+ +LH ++IH
Sbjct: 84 K-PQLAIVTQWCEGSSLYHHLHIIE--TKFEMIKLIDIARQTAQGMDYLHA---KSIIHR 137
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 138 DLKSNNIFLHEDLTVKIGDFGLA 160
>BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/143 (37%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELV---REM-CLNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L Q+L E+ L + RH NIL GYS
Sbjct: 463 IGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST 521
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P+ +V Q G SL L + + I A+G+ +LH ++IH
Sbjct: 522 K-PQLAIVTQWCEGSSLYHHLHIIE--TKFEMIKLIDIARQTAQGMDYLHA---KSIIHR 575
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 576 DLKSNNIFLHEDLTVKIGDFGLA 598
>BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/143 (37%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELV---REM-CLNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L Q+L E+ L + RH NIL GYS
Sbjct: 463 IGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST 521
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P+ +V Q G SL L + + I A+G+ +LH ++IH
Sbjct: 522 K-PQLAIVTQWCEGSSLYHHLHIIE--TKFEMIKLIDIARQTAQGMDYLHA---KSIIHR 575
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 576 DLKSNNIFLHEDLTVKIGDFGLA 598
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/143 (37%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELV---REM-CLNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L Q+L E+ L + RH NIL GYS
Sbjct: 1189 IGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST 1247
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P+ +V Q G SL L + + I A+G+ +LH ++IH
Sbjct: 1248 K-PQLAIVTQWCEGSSLYHHLHIIE--TKFEMIKLIDIARQTAQGMDYLHA---KSIIHR 1301
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 1302 DLKSNNIFLHEDLTVKIGDFGLA 1324
>AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3
protein.
Length = 651
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/143 (37%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELV---REM-CLNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L Q+L E+ L + RH NIL GYS
Sbjct: 348 IGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST 406
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P+ +V Q G SL L + + I A+G+ +LH ++IH
Sbjct: 407 K-PQLAIVTQWCEGSSLYHHLHIIE--TKFEMIKLIDIARQTAQGMDYLHA---KSIIHR 460
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 461 DLKSNNIFLHEDLTVKIGDFGLA 483
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 67.7 bits (158), Expect = 6e-11
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 11/163 (6%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMC---- 216
S+ L+L+ ++ E ++G G FG+VYKG + VA+KR R N + V C
Sbjct: 454 SHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVS 511
Query: 217 -LNQYRHDNILPLYGYSLGGP-EACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCG 274
L Q H ++ G L P + +V Q ++GGSL L + L + I
Sbjct: 512 ILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQ--SKLIIAVD 569
Query: 275 VARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
VA+G+++LH +T +IH D+ NILL + + DFG +R
Sbjct: 570 VAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGHAVVADFGESR 611
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 67.7 bits (158), Expect = 6e-11
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 11/163 (6%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMC---- 216
S+ L+L+ ++ E ++G G FG+VYKG + VA+KR R N + V C
Sbjct: 454 SHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVS 511
Query: 217 -LNQYRHDNILPLYGYSLGGP-EACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCG 274
L Q H ++ G L P + +V Q ++GGSL L + L + I
Sbjct: 512 ILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQ--SKLIIAVD 569
Query: 275 VARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
VA+G+++LH +T +IH D+ NILL + + DFG +R
Sbjct: 570 VAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGHAVVADFGESR 611
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 67.7 bits (158), Expect = 6e-11
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 11/163 (6%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMC---- 216
S+ L+L+ ++ E ++G G FG+VYKG + VA+KR R N + V C
Sbjct: 454 SHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVS 511
Query: 217 -LNQYRHDNILPLYGYSLGGP-EACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCG 274
L Q H ++ G L P + +V Q ++GGSL L + L + I
Sbjct: 512 ILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQ--SKLIIAVD 569
Query: 275 VARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
VA+G+++LH +T +IH D+ NILL + + DFG +R
Sbjct: 570 VAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGHAVVADFGESR 611
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 67.7 bits (158), Expect = 6e-11
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 11/163 (6%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMC---- 216
S+ L+L+ ++ E ++G G FG+VYKG + VA+KR R N + V C
Sbjct: 454 SHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVS 511
Query: 217 -LNQYRHDNILPLYGYSLGGP-EACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCG 274
L Q H ++ G L P + +V Q ++GGSL L + L + I
Sbjct: 512 ILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQ--SKLIIAVD 569
Query: 275 VARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
VA+G+++LH +T +IH D+ NILL + + DFG +R
Sbjct: 570 VAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGHAVVADFGESR 611
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 67.7 bits (158), Expect = 6e-11
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 11/163 (6%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMC---- 216
S+ L+L+ ++ E ++G G FG+VYKG + VA+KR R N + V C
Sbjct: 555 SHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVS 612
Query: 217 -LNQYRHDNILPLYGYSLGGP-EACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCG 274
L Q H ++ G L P + +V Q ++GGSL L + L + I
Sbjct: 613 ILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQ--SKLIIAVD 670
Query: 275 VARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
VA+G+++LH +T +IH D+ NILL + + DFG +R
Sbjct: 671 VAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGHAVVADFGESR 712
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 67.7 bits (158), Expect = 6e-11
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 11/163 (6%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMC---- 216
S+ L+L+ ++ E ++G G FG+VYKG + VA+KR R N + V C
Sbjct: 454 SHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVS 511
Query: 217 -LNQYRHDNILPLYGYSLGGP-EACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCG 274
L Q H ++ G L P + +V Q ++GGSL L + L + I
Sbjct: 512 ILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQ--SKLIIAVD 569
Query: 275 VARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
VA+G+++LH +T +IH D+ NILL + + DFG +R
Sbjct: 570 VAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGHAVVADFGESR 611
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 67.7 bits (158), Expect = 6e-11
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 11/163 (6%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMC---- 216
S+ L+L+ ++ E ++G G FG+VYKG + VA+KR R N + V C
Sbjct: 454 SHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVS 511
Query: 217 -LNQYRHDNILPLYGYSLGGP-EACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCG 274
L Q H ++ G L P + +V Q ++GGSL L + L + I
Sbjct: 512 ILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQ--SKLIIAVD 569
Query: 275 VARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
VA+G+++LH +T +IH D+ NILL + + DFG +R
Sbjct: 570 VAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGHAVVADFGESR 611
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 67.7 bits (158), Expect = 6e-11
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 11/163 (6%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMC---- 216
S+ L+L+ ++ E ++G G FG+VYKG + VA+KR R N + V C
Sbjct: 560 SHFHLQLSEIEFHE--IIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVS 617
Query: 217 -LNQYRHDNILPLYGYSLGGP-EACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCG 274
L Q H ++ G L P + +V Q ++GGSL L + L + I
Sbjct: 618 ILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQ--SKLIIAVD 675
Query: 275 VARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
VA+G+++LH +T +IH D+ NILL + + DFG +R
Sbjct: 676 VAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGHAVVADFGESR 717
>D45906-1|BAA08312.1| 638|Homo sapiens LIMK-2 protein.
Length = 638
Score = 66.9 bits (156), Expect = 1e-10
Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 149 EILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLR--DN 204
+I R S SY + D +LG+G FGQ K K G + +K L D
Sbjct: 308 DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDE 367
Query: 205 EGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLS 264
E + L + H N+L G + L+ + + GG+L+ LR D P
Sbjct: 368 ETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD---PFP 424
Query: 265 WAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
W Q+ R G+A G+ +LH+M +IH D+ N L+ + DFGL+R
Sbjct: 425 WQQKVRFAKGIASGMAYLHSM---CIIHRDLNSHNCLIKLDKTVVVADFGLSR 474
>CR456513-1|CAG30399.1| 638|Homo sapiens LIMK2 protein.
Length = 638
Score = 66.9 bits (156), Expect = 1e-10
Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 149 EILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLR--DN 204
+I R S SY + D +LG+G FGQ K K G + +K L D
Sbjct: 308 DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDE 367
Query: 205 EGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLS 264
E + L + H N+L G + L+ + + GG+L+ LR D P
Sbjct: 368 ETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD---PFP 424
Query: 265 WAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
W Q+ R G+A G+ +LH+M +IH D+ N L+ + DFGL+R
Sbjct: 425 WQQKVRFAKGIASGMAYLHSM---CIIHRDLNSHNCLIKLDKTVVVADFGLSR 474
>BC013051-1|AAH13051.1| 686|Homo sapiens LIM domain kinase 2
protein.
Length = 686
Score = 66.9 bits (156), Expect = 1e-10
Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 149 EILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLR--DN 204
+I R S SY + D +LG+G FGQ K K G + +K L D
Sbjct: 287 DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDE 346
Query: 205 EGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLS 264
E + L + H N+L G + L+ + + GG+L+ LR D P
Sbjct: 347 ETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD---PFP 403
Query: 265 WAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
W Q+ R G+A G+ +LH+M +IH D+ N L+ + DFGL+R
Sbjct: 404 WQQKVRFAKGIASGMAYLHSM---CIIHRDLNSHNCLIKLDKTVVVADFGLSR 453
>AC002073-3|AAB54055.1| 733|Homo sapiens Lim kinase protein.
Length = 733
Score = 66.9 bits (156), Expect = 1e-10
Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 149 EILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLR--DN 204
+I R S SY + D +LG+G FGQ K K G + +K L D
Sbjct: 287 DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDE 346
Query: 205 EGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLS 264
E + L + H N+L G + L+ + + GG+L+ LR D P
Sbjct: 347 ETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD---PFP 403
Query: 265 WAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
W Q+ R G+A G+ +LH+M +IH D+ N L+ + DFGL+R
Sbjct: 404 WQQKVRFAKGIASGMAYLHSM---CIIHRDLNSHNCLIKLDKTVVVADFGLSR 453
>AC002073-2|AAB54056.1| 638|Homo sapiens Lim Kinase protein.
Length = 638
Score = 66.9 bits (156), Expect = 1e-10
Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 149 EILRKVSAIPKMSYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLR--DN 204
+I R S SY + D +LG+G FGQ K K G + +K L D
Sbjct: 308 DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDE 367
Query: 205 EGRDQELVREMCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLS 264
E + L + H N+L G + L+ + + GG+L+ LR D P
Sbjct: 368 ETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD---PFP 424
Query: 265 WAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
W Q+ R G+A G+ +LH+M +IH D+ N L+ + DFGL+R
Sbjct: 425 WQQKVRFAKGIASGMAYLHSM---CIIHRDLNSHNCLIKLDKTVVVADFGLSR 474
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 66.5 bits (155), Expect = 1e-10
Identities = 48/154 (31%), Positives = 77/154 (50%), Gaps = 14/154 (9%)
Query: 173 SERNLLGRGGFGQVYKGEWKL------LGVAVKRLRDNEGRDQE---LVREMCLNQYRHD 223
+ + ++G G FG+VYKG K + VA+K L+ Q L + Q+ H
Sbjct: 614 TRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHH 673
Query: 224 NILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLH 283
NI+ L G ++ + M G+L++ LR KDG S Q ++ G+A G+++L
Sbjct: 674 NIIRLEGVISKYKPMMIITEYMENGALDKFLREKDG--EFSVLQLVGMLRGIAAGMKYLA 731
Query: 284 TMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
M +H D+ NIL++ L K+ DFGL+R
Sbjct: 732 NMN---YVHRDLAARNILVNSNLVCKVSDFGLSR 762
>M19722-1|AAA52451.1| 529|Homo sapiens FGR protein.
Length = 529
Score = 66.5 bits (155), Expect = 1e-10
Identities = 64/192 (33%), Positives = 87/192 (45%), Gaps = 17/192 (8%)
Query: 160 MSYEELRLATDDWS--------ERNLLGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQE 210
M + L LA D W ER L G G FG V+ G W VAVK L+ +
Sbjct: 244 MKPQTLGLAKDAWEISRSSITLERRL-GTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKA 302
Query: 211 LVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC 269
+ E + RHD ++ LY P +V + M GSL L+ +G L Q
Sbjct: 303 FLEEAQVMKLLRHDKLVQLYAVVSEEP-IYIVTEFMCHGSLLDFLKNPEGQ-DLRLPQLV 360
Query: 270 RIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLK 329
+ VA G+ ++ M IH D++ ANIL+ + L KI DFGLAR DE +
Sbjct: 361 DMAAQVAEGMAYMERMN---YIHRDLRAANILVGERLACKIADFGLARL-IKDDEYNPCQ 416
Query: 330 VSRFPKEPNARE 341
S+FP + A E
Sbjct: 417 GSKFPIKWTAPE 428
>L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 998
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H N++ L
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G G +V + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFLRKHDG--QFTVIQLVGMLRGIAAGMRYLADM--- 752
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 753 GYVHRDLAARNILVNSNLVCKVSDFGLSR 781
>BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H N++ L
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G G +V + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFLRKHDG--QFTVIQLVGMLRGIAAGMRYLADM--- 752
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 753 GYVHRDLAARNILVNSNLVCKVSDFGLSR 781
>BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H N++ L
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G G +V + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFLRKHDG--QFTVIQLVGMLRGIAAGMRYLADM--- 752
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 753 GYVHRDLAARNILVNSNLVCKVSDFGLSR 781
>BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 66.5 bits (155), Expect = 1e-10
Identities = 64/192 (33%), Positives = 87/192 (45%), Gaps = 17/192 (8%)
Query: 160 MSYEELRLATDDWS--------ERNLLGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQE 210
M + L LA D W ER L G G FG V+ G W VAVK L+ +
Sbjct: 244 MKPQTLGLAKDAWEISRSSITLERRL-GTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKA 302
Query: 211 LVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC 269
+ E + RHD ++ LY P +V + M GSL L+ +G L Q
Sbjct: 303 FLEEAQVMKLLRHDKLVQLYAVVSEEP-IYIVTEFMCHGSLLDFLKNPEGQ-DLRLPQLV 360
Query: 270 RIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLK 329
+ VA G+ ++ M IH D++ ANIL+ + L KI DFGLAR DE +
Sbjct: 361 DMAAQVAEGMAYMERMN---YIHRDLRAANILVGERLACKIADFGLARL-IKDDEYNPCQ 416
Query: 330 VSRFPKEPNARE 341
S+FP + A E
Sbjct: 417 GSKFPIKWTAPE 428
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 66.5 bits (155), Expect = 1e-10
Identities = 48/154 (31%), Positives = 77/154 (50%), Gaps = 14/154 (9%)
Query: 173 SERNLLGRGGFGQVYKGEWKL------LGVAVKRLRDNEGRDQE---LVREMCLNQYRHD 223
+ + ++G G FG+VYKG K + VA+K L+ Q L + Q+ H
Sbjct: 614 TRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHH 673
Query: 224 NILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLH 283
NI+ L G ++ + M G+L++ LR KDG S Q ++ G+A G+++L
Sbjct: 674 NIIRLEGVISKYKPMMIITEYMENGALDKFLREKDG--EFSVLQLVGMLRGIAAGMKYLA 731
Query: 284 TMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
M +H D+ NIL++ L K+ DFGL+R
Sbjct: 732 NMN---YVHRDLAARNILVNSNLVCKVSDFGLSR 762
>AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H N++ L
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G G +V + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFLRKHDG--QFTVIQLVGMLRGIAAGMRYLADM--- 752
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 753 GYVHRDLAARNILVNSNLVCKVSDFGLSR 781
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 66.5 bits (155), Expect = 1e-10
Identities = 48/154 (31%), Positives = 77/154 (50%), Gaps = 14/154 (9%)
Query: 173 SERNLLGRGGFGQVYKGEWKL------LGVAVKRLRDNEGRDQE---LVREMCLNQYRHD 223
+ + ++G G FG+VYKG K + VA+K L+ Q L + Q+ H
Sbjct: 614 TRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHH 673
Query: 224 NILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLH 283
NI+ L G ++ + M G+L++ LR KDG S Q ++ G+A G+++L
Sbjct: 674 NIIRLEGVISKYKPMMIITEYMENGALDKFLREKDG--EFSVLQLVGMLRGIAAGMKYLA 731
Query: 284 TMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
M +H D+ NIL++ L K+ DFGL+R
Sbjct: 732 NMN---YVHRDLAARNILVNSNLVCKVSDFGLSR 762
>AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H N++ L
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G G +V + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFLRKHDG--QFTVIQLVGMLRGIAAGMRYLADM--- 752
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 753 GYVHRDLAARNILVNSNLVCKVSDFGLSR 781
>AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H N++ L
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G G +V + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFLRKHDG--QFTVIQLVGMLRGIAAGMRYLADM--- 752
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 753 GYVHRDLAARNILVNSNLVCKVSDFGLSR 781
>AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 66.5 bits (155), Expect = 1e-10
Identities = 64/192 (33%), Positives = 87/192 (45%), Gaps = 17/192 (8%)
Query: 160 MSYEELRLATDDWS--------ERNLLGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQE 210
M + L LA D W ER L G G FG V+ G W VAVK L+ +
Sbjct: 244 MKPQTLGLAKDAWEISRSSITLERRL-GTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKA 302
Query: 211 LVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC 269
+ E + RHD ++ LY P +V + M GSL L+ +G L Q
Sbjct: 303 FLEEAQVMKLLRHDKLVQLYAVVSEEP-IYIVTEFMCHGSLLDFLKNPEGQ-DLRLPQLV 360
Query: 270 RIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLK 329
+ VA G+ ++ M IH D++ ANIL+ + L KI DFGLAR DE +
Sbjct: 361 DMAAQVAEGMAYMERMN---YIHRDLRAANILVGERLACKIADFGLARL-IKDDEYNPCQ 416
Query: 330 VSRFPKEPNARE 341
S+FP + A E
Sbjct: 417 GSKFPIKWTAPE 428
>AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7
variant protein.
Length = 1000
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H N++ L
Sbjct: 640 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 699
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G G +V + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 700 EGVVTRGKPVMIVIEFMENGALDAFLRKHDG--QFTVIQLVGMLRGIAAGMRYLADM--- 754
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 755 GYVHRDLAARNILVNSNLVCKVSDFGLSR 783
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 627 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 687 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 742
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 743 -YVHRDLAARNILVNSNLVCKVSDFGLSR 770
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 610 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 669
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 670 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 725
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 726 -YVHRDLAARNILVNSNLVCKVSDFGLSR 753
>L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kinase
protein.
Length = 1036
Score = 66.1 bits (154), Expect = 2e-10
Identities = 61/173 (35%), Positives = 82/173 (47%), Gaps = 20/173 (11%)
Query: 178 LGRGGFGQVYKGEW-----KLLGVAVKRLRDN-----EGRDQELVREM-CLNQYRHDNIL 226
LG G FG V +GEW K + VAVK L+ + E D + +RE+ ++ H N++
Sbjct: 132 LGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMD-DFIREVNAMHSLDHRNLI 190
Query: 227 PLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMT 286
LYG L P +V +L GSL RLR G L R + VA G+ +L +
Sbjct: 191 RLYGVVLTPPMK-MVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ--VAEGMGYLES-- 245
Query: 287 GSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNA 339
IH D+ N+LL KIGDFGL R P D+ H + K P A
Sbjct: 246 -KRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDD--HYVMQEHRKVPFA 295
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 118 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 177
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 178 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 233
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 234 -YVHRDLAARNILVNSNLVCKVSDFGLSR 261
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 621 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 680
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 681 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 736
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 737 -YVHRDLAARNILVNSNLVCKVSDFGLSR 764
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 90 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 143 RDIKAANVLLSEHGEVKLADFGVA 166
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 90 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 143 RDIKAANVLLSEHGEVKLADFGVA 166
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 90 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 143 RDIKAANVLLSEHGEVKLADFGVA 166
>BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein.
Length = 528
Score = 66.1 bits (154), Expect = 2e-10
Identities = 61/173 (35%), Positives = 82/173 (47%), Gaps = 20/173 (11%)
Query: 178 LGRGGFGQVYKGEW-----KLLGVAVKRLRDN-----EGRDQELVREM-CLNQYRHDNIL 226
LG G FG V +GEW K + VAVK L+ + E D + +RE+ ++ H N++
Sbjct: 132 LGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMD-DFIREVNAMHSLDHRNLI 190
Query: 227 PLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMT 286
LYG L P +V +L GSL RLR G L R + VA G+ +L +
Sbjct: 191 RLYGVVLTPPMK-MVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ--VAEGMGYLES-- 245
Query: 287 GSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNA 339
IH D+ N+LL KIGDFGL R P D+ H + K P A
Sbjct: 246 -KRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDD--HYVMQEHRKVPFA 295
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 741
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 742 -YVHRDLAARNILVNSNLVCKVSDFGLSR 769
>AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 627 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 687 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 742
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 743 -YVHRDLAARNILVNSNLVCKVSDFGLSR 770
>AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 741
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 742 -YVHRDLAARNILVNSNLVCKVSDFGLSR 769
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 621 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 680
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 681 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 736
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 737 -YVHRDLAARNILVNSNLVCKVSDFGLSR 764
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 90 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 143 RDIKAANVLLSEHGEVKLADFGVA 166
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 42 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 101
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 102 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 154
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 155 RDIKAANVLLSEHGEVKLADFGVA 178
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 741
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 742 -YVHRDLAARNILVNSNLVCKVSDFGLSR 769
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 741
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 742 -YVHRDLAARNILVNSNLVCKVSDFGLSR 769
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 627 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 687 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 742
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 743 -YVHRDLAARNILVNSNLVCKVSDFGLSR 770
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 90 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 143 RDIKAANVLLSEHGEVKLADFGVA 166
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 42 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 101
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 102 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 154
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 155 RDIKAANVLLSEHGEVKLADFGVA 178
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 741
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 742 -YVHRDLAARNILVNSNLVCKVSDFGLSR 769
>AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 627 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 687 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 742
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 743 -YVHRDLAARNILVNSNLVCKVSDFGLSR 770
>AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 741
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 742 -YVHRDLAARNILVNSNLVCKVSDFGLSR 769
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 621 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 680
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 681 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 736
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 737 -YVHRDLAARNILVNSNLVCKVSDFGLSR 764
>AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens
cDNA FLJ16772 fis, clone BRAWH3043827, highly similar
to Homo sapiens activated p21cdc42Hs kinase (ACK1). ).
Length = 1086
Score = 66.1 bits (154), Expect = 2e-10
Identities = 61/173 (35%), Positives = 82/173 (47%), Gaps = 20/173 (11%)
Query: 178 LGRGGFGQVYKGEW-----KLLGVAVKRLRDN-----EGRDQELVREM-CLNQYRHDNIL 226
LG G FG V +GEW K + VAVK L+ + E D + +RE+ ++ H N++
Sbjct: 195 LGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMD-DFIREVNAMHSLDHRNLI 253
Query: 227 PLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMT 286
LYG L P +V +L GSL RLR G L R + VA G+ +L +
Sbjct: 254 RLYGVVLTPPMK-MVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ--VAEGMGYLES-- 308
Query: 287 GSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNA 339
IH D+ N+LL KIGDFGL R P D+ H + K P A
Sbjct: 309 -KRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDD--HYVMQEHRKVPFA 358
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 42 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 101
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 102 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 154
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 155 RDIKAANVLLSEHGEVKLADFGVA 178
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 741
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 742 -YVHRDLAARNILVNSNLVCKVSDFGLSR 769
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 90 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ DFG+A
Sbjct: 143 RDIKAANVLLSEHGEVKLADFGVA 166
>AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein
protein.
Length = 1004
Score = 66.1 bits (154), Expect = 2e-10
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNEGRDQE---LVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ Q L + Q+ H N++ L
Sbjct: 644 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 703
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M GSL+ LR DG + Q ++ G+A G+++L M
Sbjct: 704 EGVVTKSTPVMIITEFMENGSLDSFLRQNDG--QFTVIQLVGMLRGIAAGMKYLADMN-- 759
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 760 -YVHRDLAARNILVNSNLVCKVSDFGLSR 787
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/168 (32%), Positives = 76/168 (45%), Gaps = 13/168 (7%)
Query: 166 RLATDDWSERNLLGRGGFGQVYKGEWK------LLGVAVKRLRDNEGRDQELVREMCLNQ 219
RL DD+ LG+G FG VY K L V K + EG + +L RE+ +
Sbjct: 3 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQA 62
Query: 220 Y-RHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARG 278
+ +H NIL LY Y L+ + G L + L+ + L + I+ VA
Sbjct: 63 HLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSE---KLDEQRTATIIEEVADA 119
Query: 279 LQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERT 326
L + H +IH DIKP N+LL E KI DFG + P + +T
Sbjct: 120 LTYCHD---KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERKT 164
>AB209655-1|BAD92892.1| 310|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 310
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/147 (33%), Positives = 70/147 (47%), Gaps = 21/147 (14%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQY 220
S++ELRL ++G GGFG+VY+G W+ VAVK R + D + E +
Sbjct: 151 SFQELRL-------EEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEA 203
Query: 221 R------HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRL--RPKDGAAPLSWAQRCRIM 272
R H NI+ L L P CLV + AGG L + L R ++WA +
Sbjct: 204 RLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQ---- 259
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPAN 299
+ARG+ +LH +IH D+K N
Sbjct: 260 --IARGMHYLHCEALVPVIHRDLKSNN 284
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 65.3 bits (152), Expect = 3e-10
Identities = 51/164 (31%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPE 237
+G G FG V +GE+ VAVK ++ + L + + +H+N++ L G L
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILH-QG 299
Query: 238 ACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKP 297
+V + ++ G+L LR + G A ++ AQ + VA G+++L + L+H D+
Sbjct: 300 LYIVMEHVSKGNLVNFLRTR-GRALVNTAQLLQFSLHVAEGMEYLES---KKLVHRDLAA 355
Query: 298 ANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
NIL+ + L K+ DFGLA+ ER L SR P + A E
Sbjct: 356 RNILVSEDLVAKVSDFGLAKA-----ERKGLDSSRLPVKWTAPE 394
>U50062-1|AAC32232.1| 671|Homo sapiens RIP protein kinase protein.
Length = 671
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/164 (29%), Positives = 84/164 (51%), Gaps = 11/164 (6%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQV----YKGEWKLLGVAVKRLRDNEGRDQELVR 213
P MS +++ + D+ E L GGFG+V ++ + ++ V + + ++ L+
Sbjct: 3 PDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLE 62
Query: 214 EM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIM 272
E +N+ RH ++ L G + + LV + M G+L L+ + + PLS + RI+
Sbjct: 63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKA-EMSTPLS--VKGRII 119
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
+ G+ +LH G +IH D+KP NIL+D KI D GLA
Sbjct: 120 LEIIEGMCYLH---GKGVIHKDLKPENILVDNDFHIKIADLGLA 160
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 65.3 bits (152), Expect = 3e-10
Identities = 51/164 (31%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPE 237
+G G FG V +GE+ VAVK ++ + L + + +H+N++ L G L
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILH-QG 299
Query: 238 ACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKP 297
+V + ++ G+L LR + G A ++ AQ + VA G+++L + L+H D+
Sbjct: 300 LYIVMEHVSKGNLVNFLRTR-GRALVNTAQLLQFSLHVAEGMEYLES---KKLVHRDLAA 355
Query: 298 ANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
NIL+ + L K+ DFGLA+ ER L SR P + A E
Sbjct: 356 RNILVSEDLVAKVSDFGLAKA-----ERKGLDSSRLPVKWTAPE 394
>L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 65.3 bits (152), Expect = 3e-10
Identities = 51/164 (31%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPE 237
+G G FG V +GE+ VAVK ++ + L + + +H+N++ L G L
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILH-QG 299
Query: 238 ACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKP 297
+V + ++ G+L LR + G A ++ AQ + VA G+++L + L+H D+
Sbjct: 300 LYIVMEHVSKGNLVNFLRTR-GRALVNTAQLLQFSLHVAEGMEYLES---KKLVHRDLAA 355
Query: 298 ANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
NIL+ + L K+ DFGLA+ ER L SR P + A E
Sbjct: 356 RNILVSEDLVAKVSDFGLAKA-----ERKGLDSSRLPVKWTAPE 394
>BC126256-1|AAI26257.1| 671|Homo sapiens receptor
(TNFRSF)-interacting serine-threonine kinase 1 protein.
Length = 671
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/164 (29%), Positives = 84/164 (51%), Gaps = 11/164 (6%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQV----YKGEWKLLGVAVKRLRDNEGRDQELVR 213
P MS +++ + D+ E L GGFG+V ++ + ++ V + + ++ L+
Sbjct: 3 PDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLE 62
Query: 214 EM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIM 272
E +N+ RH ++ L G + + LV + M G+L L+ + + PLS + RI+
Sbjct: 63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKA-EMSTPLS--VKGRII 119
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
+ G+ +LH G +IH D+KP NIL+D KI D GLA
Sbjct: 120 LEIIEGMCYLH---GKGVIHKDLKPENILVDNDFHIKIADLGLA 160
>BC126254-1|AAI26255.1| 671|Homo sapiens receptor
(TNFRSF)-interacting serine-threonine kinase 1 protein.
Length = 671
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/164 (29%), Positives = 84/164 (51%), Gaps = 11/164 (6%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQV----YKGEWKLLGVAVKRLRDNEGRDQELVR 213
P MS +++ + D+ E L GGFG+V ++ + ++ V + + ++ L+
Sbjct: 3 PDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLE 62
Query: 214 EM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIM 272
E +N+ RH ++ L G + + LV + M G+L L+ + + PLS + RI+
Sbjct: 63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKA-EMSTPLS--VKGRII 119
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
+ G+ +LH G +IH D+KP NIL+D KI D GLA
Sbjct: 120 LEIIEGMCYLH---GKGVIHKDLKPENILVDNDFHIKIADLGLA 160
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 65.3 bits (152), Expect = 3e-10
Identities = 51/164 (31%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPE 237
+G G FG V +GE+ VAVK ++ + L + + +H+N++ L G L
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILH-QG 299
Query: 238 ACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKP 297
+V + ++ G+L LR + G A ++ AQ + VA G+++L + L+H D+
Sbjct: 300 LYIVMEHVSKGNLVNFLRTR-GRALVNTAQLLQFSLHVAEGMEYLES---KKLVHRDLAA 355
Query: 298 ANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
NIL+ + L K+ DFGLA+ ER L SR P + A E
Sbjct: 356 RNILVSEDLVAKVSDFGLAKA-----ERKGLDSSRLPVKWTAPE 394
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 65.3 bits (152), Expect = 3e-10
Identities = 51/164 (31%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPE 237
+G G FG V +GE+ VAVK ++ + L + + +H+N++ L G L
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILH-QG 299
Query: 238 ACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKP 297
+V + ++ G+L LR + G A ++ AQ + VA G+++L + L+H D+
Sbjct: 300 LYIVMEHVSKGNLVNFLRTR-GRALVNTAQLLQFSLHVAEGMEYLES---KKLVHRDLAA 355
Query: 298 ANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
NIL+ + L K+ DFGLA+ ER L SR P + A E
Sbjct: 356 RNILVSEDLVAKVSDFGLAKA-----ERKGLDSSRLPVKWTAPE 394
>AY682848-1|AAT74626.1| 671|Homo sapiens receptor
(TNFRSF)-interacting serine-threonine kinase 1 protein.
Length = 671
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/164 (29%), Positives = 84/164 (51%), Gaps = 11/164 (6%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQV----YKGEWKLLGVAVKRLRDNEGRDQELVR 213
P MS +++ + D+ E L GGFG+V ++ + ++ V + + ++ L+
Sbjct: 3 PDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLE 62
Query: 214 EM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIM 272
E +N+ RH ++ L G + + LV + M G+L L+ + + PLS + RI+
Sbjct: 63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKA-EMSTPLS--VKGRII 119
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
+ G+ +LH G +IH D+KP NIL+D KI D GLA
Sbjct: 120 LEIIEGMCYLH---GKGVIHKDLKPENILVDNDFHIKIADLGLA 160
>AL031963-3|CAD70625.1| 671|Homo sapiens receptor
(TNFRSF)-interacting serine-threonine kinase 1 protein.
Length = 671
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/164 (29%), Positives = 84/164 (51%), Gaps = 11/164 (6%)
Query: 158 PKMSYEELRLATDDWSERNLLGRGGFGQV----YKGEWKLLGVAVKRLRDNEGRDQELVR 213
P MS +++ + D+ E L GGFG+V ++ + ++ V + + ++ L+
Sbjct: 3 PDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLE 62
Query: 214 EM-CLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIM 272
E +N+ RH ++ L G + + LV + M G+L L+ + + PLS + RI+
Sbjct: 63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKA-EMSTPLS--VKGRII 119
Query: 273 CGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
+ G+ +LH G +IH D+KP NIL+D KI D GLA
Sbjct: 120 LEIIEGMCYLH---GKGVIHKDLKPENILVDNDFHIKIADLGLA 160
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 65.3 bits (152), Expect = 3e-10
Identities = 51/164 (31%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYRHDNILPLYGYSLGGPE 237
+G G FG V +GE+ VAVK ++ + L + + +H+N++ L G L
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILH-QG 299
Query: 238 ACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKP 297
+V + ++ G+L LR + G A ++ AQ + VA G+++L + L+H D+
Sbjct: 300 LYIVMEHVSKGNLVNFLRTR-GRALVNTAQLLQFSLHVAEGMEYLES---KKLVHRDLAA 355
Query: 298 ANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
NIL+ + L K+ DFGLA+ ER L SR P + A E
Sbjct: 356 RNILVSEDLVAKVSDFGLAKA-----ERKGLDSSRLPVKWTAPE 394
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 64.9 bits (151), Expect = 4e-10
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDN--EGRDQELVREMCL-NQYRHDNILPL 228
++G G FG+V +G K G VA+K L+ E + +E + E + Q+ H NI+ L
Sbjct: 620 VIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 680 EGVVTNSMPVMILTEFMENGALDSFLRLNDG--QFTVIQLVGMLRGIASGMRYLAEM--- 734
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+ +H D+ NIL++ L K+ DFGL+R
Sbjct: 735 SYVHRDLAARNILVNSNLVCKVSDFGLSR 763
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 64.9 bits (151), Expect = 4e-10
Identities = 55/177 (31%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Query: 159 KMSYEELRLATDDWSERNLLGRGGFGQVYKGEWK------LLGVAVKRLRDNEGRDQELV 212
KM ++ +A +D+ LG+G FG VY K L V K + G + +L
Sbjct: 119 KMKNQKEAVALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLR 178
Query: 213 REMCLNQY-RHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRI 271
RE+ + + RH NIL LYGY +A VY ++ L R + + +
Sbjct: 179 REVEIQSHLRHPNILRLYGYF---HDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANL 235
Query: 272 MCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHL 328
+A L + H+ +IH DIKP N+LL E KI DFG + P RT L
Sbjct: 236 YNRIANALSYCHS---KRVIHRDIKPENLLLGSAGELKIADFGWSVHAP-SSRRTTL 288
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 64.9 bits (151), Expect = 4e-10
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDN--EGRDQELVREMCL-NQYRHDNILPL 228
++G G FG+V +G K G VA+K L+ E + +E + E + Q+ H NI+ L
Sbjct: 620 VIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 680 EGVVTNSMPVMILTEFMENGALDSFLRLNDG--QFTVIQLVGMLRGIASGMRYLAEM--- 734
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+ +H D+ NIL++ L K+ DFGL+R
Sbjct: 735 SYVHRDLAARNILVNSNLVCKVSDFGLSR 763
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 64.9 bits (151), Expect = 4e-10
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDN--EGRDQELVREMCL-NQYRHDNILPL 228
++G G FG+V +G K G VA+K L+ E + +E + E + Q+ H NI+ L
Sbjct: 478 VIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 537
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 538 EGVVTNSMPVMILTEFMENGALDSFLRLNDG--QFTVIQLVGMLRGIASGMRYLAEM--- 592
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+ +H D+ NIL++ L K+ DFGL+R
Sbjct: 593 SYVHRDLAARNILVNSNLVCKVSDFGLSR 621
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 64.9 bits (151), Expect = 4e-10
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDN--EGRDQELVREMCL-NQYRHDNILPL 228
++G G FG+V +G K G VA+K L+ E + +E + E + Q+ H NI+ L
Sbjct: 620 VIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 680 EGVVTNSMPVMILTEFMENGALDSFLRLNDG--QFTVIQLVGMLRGIASGMRYLAEM--- 734
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+ +H D+ NIL++ L K+ DFGL+R
Sbjct: 735 SYVHRDLAARNILVNSNLVCKVSDFGLSR 763
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 64.9 bits (151), Expect = 4e-10
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDN--EGRDQELVREMCL-NQYRHDNILPL 228
++G G FG+V +G K G VA+K L+ E + +E + E + Q+ H NI+ L
Sbjct: 620 VIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 680 EGVVTNSMPVMILTEFMENGALDSFLRLNDG--QFTVIQLVGMLRGIASGMRYLAEM--- 734
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+ +H D+ NIL++ L K+ DFGL+R
Sbjct: 735 SYVHRDLAARNILVNSNLVCKVSDFGLSR 763
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 64.9 bits (151), Expect = 4e-10
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDN--EGRDQELVREMCL-NQYRHDNILPL 228
++G G FG+V +G K G VA+K L+ E + +E + E + Q+ H NI+ L
Sbjct: 620 VIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 680 EGVVTNSMPVMILTEFMENGALDSFLRLNDG--QFTVIQLVGMLRGIASGMRYLAEM--- 734
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+ +H D+ NIL++ L K+ DFGL+R
Sbjct: 735 SYVHRDLAARNILVNSNLVCKVSDFGLSR 763
>AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4
precursor variant protein.
Length = 986
Score = 64.9 bits (151), Expect = 4e-10
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDN--EGRDQELVREMCL-NQYRHDNILPL 228
++G G FG+V +G K G VA+K L+ E + +E + E + Q+ H NI+ L
Sbjct: 619 VIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 678
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR DG + Q ++ G+A G+++L M
Sbjct: 679 EGVVTNSMPVMILTEFMENGALDSFLRLNDG--QFTVIQLVGMLRGIASGMRYLAEM--- 733
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+ +H D+ NIL++ L K+ DFGL+R
Sbjct: 734 SYVHRDLAARNILVNSNLVCKVSDFGLSR 762
>M12724-1|AAA52762.1| 306|Homo sapiens FGR protein.
Length = 306
Score = 64.5 bits (150), Expect = 6e-10
Identities = 57/168 (33%), Positives = 77/168 (45%), Gaps = 16/168 (9%)
Query: 160 MSYEELRLATDDWS--------ERNLLGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQE 210
M + L LA D W ER L G G FG V+ G W VAVK L+ +
Sbjct: 134 MKPQTLGLAKDAWEISRSSITLERRL-GTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKA 192
Query: 211 LVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRC 269
+ E + RHD ++ LY P +V + M GSL L+ +G L Q
Sbjct: 193 FLEEAQVMKLLRHDKLVQLYAVVSEEP-IYIVTEFMCHGSLLDFLKNPEGQ-DLRLPQLV 250
Query: 270 RIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+ VA G+ ++ M IH D++ ANIL+ + L KI DFGLAR
Sbjct: 251 DMAAQVAEGMAYMERMN---YIHRDLRAANILVGERLACKIADFGLAR 295
>Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 64.1 bits (149), Expect = 7e-10
Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEG---RDQELVREM-CLNQYRHDNILPLYGYSL 233
+G G FG V++G W VAVK L+ ++ + Q EM L + RH NIL G+ +
Sbjct: 316 IGTGSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGF-M 373
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P ++ Q G SL L D Q + A+G+ +LH +IH
Sbjct: 374 TRPGFAIITQWCEGSSLYHHLHVAD--TRFDMVQLIDVARQTAQGMDYLHAKN---IIHR 428
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 429 DLKSNNIFLHEGLTVKIGDFGLA 451
>X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for
A-raf-1 oncogene. ).
Length = 606
Score = 64.1 bits (149), Expect = 7e-10
Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEG---RDQELVREM-CLNQYRHDNILPLYGYSL 233
+G G FG V++G W VAVK L+ ++ + Q EM L + RH NIL G+ +
Sbjct: 316 IGTGSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGF-M 373
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P ++ Q G SL L D Q + A+G+ +LH +IH
Sbjct: 374 TRPGFAIITQWCEGSSLYHHLHVAD--TRFDMVQLIDVARQTAQGMDYLHAKN---IIHR 428
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 429 DLKSNNIFLHEGLTVKIGDFGLA 451
>X02647-1|CAA26485.1| 351|Homo sapiens c-src protein.
Length = 351
Score = 64.1 bits (149), Expect = 7e-10
Identities = 61/211 (28%), Positives = 100/211 (47%), Gaps = 17/211 (8%)
Query: 142 AQYDKYDEIL--RKVSAIPKMSYEELRLATDDWS--ERNL-----LGRGGFGQVYKGEWK 192
A Y K+ + L R + P + LA D W +L LG+G FG+V+ G W
Sbjct: 46 AYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWN 105
Query: 193 -LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSL 250
VA+K L+ + ++E + + RH+ ++ LY P +V + M+ GSL
Sbjct: 106 GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMSKGSL 164
Query: 251 EQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKI 310
L+ + G L Q + +A G+ ++ M +H D++ ANIL+ + L K+
Sbjct: 165 LDFLKGETGKY-LRLPQLVDMAAQIASGMAYVERMN---YVHRDLRAANILVGENLVCKV 220
Query: 311 GDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
DFGLAR +E T + ++FP + A E
Sbjct: 221 ADFGLARL-IEDNEYTARQGAKFPIKWTAPE 250
>U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein.
Length = 633
Score = 64.1 bits (149), Expect = 7e-10
Identities = 49/180 (27%), Positives = 85/180 (47%), Gaps = 12/180 (6%)
Query: 177 LLGRGGFGQVYKGEWKLLG---VAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYS 232
+LG+G FGQ K + G V + +R +E + ++E+ + H N+L G
Sbjct: 330 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVL 389
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ + + GG+L ++ D P W+QR +A G+ +LH+M +IH
Sbjct: 390 YKDKRLNFITEYIKGGTLRGIIKSMDSQYP--WSQRVSFAKDIASGMAYLHSMN---IIH 444
Query: 293 GDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNAREQWIDVTGRGNW 352
D+ N L+ + + DFGLAR DE+T + R K+P+ ++++ V G W
Sbjct: 445 RDLNSHNCLVRENKNVVVADFGLARL--MVDEKTQPEGLRSLKKPDRKKRY-TVVGNPYW 501
>U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein.
Length = 647
Score = 64.1 bits (149), Expect = 7e-10
Identities = 49/180 (27%), Positives = 85/180 (47%), Gaps = 12/180 (6%)
Query: 177 LLGRGGFGQVYKGEWKLLG---VAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYS 232
+LG+G FGQ K + G V + +R +E + ++E+ + H N+L G
Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVL 403
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ + + GG+L ++ D P W+QR +A G+ +LH+M +IH
Sbjct: 404 YKDKRLNFITEYIKGGTLRGIIKSMDSQYP--WSQRVSFAKDIASGMAYLHSMN---IIH 458
Query: 293 GDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNAREQWIDVTGRGNW 352
D+ N L+ + + DFGLAR DE+T + R K+P+ ++++ V G W
Sbjct: 459 RDLNSHNCLVRENKNVVVADFGLARL--MVDEKTQPEGLRSLKKPDRKKRY-TVVGNPYW 515
>U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced
LIM-kinase1 protein.
Length = 633
Score = 64.1 bits (149), Expect = 7e-10
Identities = 49/180 (27%), Positives = 85/180 (47%), Gaps = 12/180 (6%)
Query: 177 LLGRGGFGQVYKGEWKLLG---VAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYS 232
+LG+G FGQ K + G V + +R +E + ++E+ + H N+L G
Sbjct: 330 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVL 389
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ + + GG+L ++ D P W+QR +A G+ +LH+M +IH
Sbjct: 390 YKDKRLNFITEYIKGGTLRGIIKSMDSQYP--WSQRVSFAKDIASGMAYLHSMN---IIH 444
Query: 293 GDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNAREQWIDVTGRGNW 352
D+ N L+ + + DFGLAR DE+T + R K+P+ ++++ V G W
Sbjct: 445 RDLNSHNCLVRENKNVVVADFGLARL--MVDEKTQPEGLRSLKKPDRKKRY-TVVGNPYW 501
>U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein.
Length = 647
Score = 64.1 bits (149), Expect = 7e-10
Identities = 49/180 (27%), Positives = 85/180 (47%), Gaps = 12/180 (6%)
Query: 177 LLGRGGFGQVYKGEWKLLG---VAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYS 232
+LG+G FGQ K + G V + +R +E + ++E+ + H N+L G
Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVL 403
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ + + GG+L ++ D P W+QR +A G+ +LH+M +IH
Sbjct: 404 YKDKRLNFITEYIKGGTLRGIIKSMDSQYP--WSQRVSFAKDIASGMAYLHSMN---IIH 458
Query: 293 GDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNAREQWIDVTGRGNW 352
D+ N L+ + + DFGLAR DE+T + R K+P+ ++++ V G W
Sbjct: 459 RDLNSHNCLVRENKNVVVADFGLARL--MVDEKTQPEGLRSLKKPDRKKRY-TVVGNPYW 515
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 6/142 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG G FG+V++G W VAVK L+ + +RE + RH ++ LY
Sbjct: 240 LGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLE 299
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
++ +LM GSL++ L+ D + + Q+ + VA G+ +L + IH D+
Sbjct: 300 DPIYIITELMRHGSLQEYLQ-NDTGSKIHLTQQVDMAAQVASGMAYLESRN---YIHRDL 355
Query: 296 KPANILLDQCLEPKIGDFGLAR 317
N+L+ + K+ DFGLAR
Sbjct: 356 AARNVLVGEHNIYKVADFGLAR 377
>U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase
protein.
Length = 606
Score = 64.1 bits (149), Expect = 7e-10
Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEG---RDQELVREM-CLNQYRHDNILPLYGYSL 233
+G G FG V++G W VAVK L+ ++ + Q EM L + RH NIL G+ +
Sbjct: 316 IGTGSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGF-M 373
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P ++ Q G SL L D Q + A+G+ +LH +IH
Sbjct: 374 TRPGFAIITQWCEGSSLYHHLHVAD--TRFDMVQLIDVARQTAQGMDYLHAKN---IIHR 428
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 429 DLKSNNIFLHEGLTVKIGDFGLA 451
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 6/142 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG G FG+V++G W VAVK L+ + +RE + RH ++ LY
Sbjct: 240 LGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLE 299
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
++ +LM GSL++ L+ D + + Q+ + VA G+ +L + IH D+
Sbjct: 300 DPIYIITELMRHGSLQEYLQ-NDTGSKIHLTQQVDMAAQVASGMAYLESRN---YIHRDL 355
Query: 296 KPANILLDQCLEPKIGDFGLAR 317
N+L+ + K+ DFGLAR
Sbjct: 356 AARNVLVGEHNIYKVADFGLAR 377
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 64.1 bits (149), Expect = 7e-10
Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKL-----LGVAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL + VA+K L+ + R L + Q+ H NI+ L
Sbjct: 626 VVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G +V + M GSL+ LR D A + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSKPVMIVTEYMENGSLDSFLRKHD--AQFTVIQLVGMLRGIASGMKYLSDM--- 740
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 741 GYVHRDLAARNILINSNLVCKVSDFGLSR 769
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 64.1 bits (149), Expect = 7e-10
Identities = 53/167 (31%), Positives = 81/167 (48%), Gaps = 8/167 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG G FG+V+ G W VA+K L+ + + E + + +HD ++ LY
Sbjct: 277 LGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + M GSL L+ +G A L + VA G+ ++ M IH D+
Sbjct: 337 P-IYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAAGMAYIERMN---YIHRDL 391
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNAREQ 342
+ ANIL+ L KI DFGLAR +E T + ++FP + A E+
Sbjct: 392 RSANILVGNGLICKIADFGLARL-IEDNEYTARQGAKFPIKWTAPER 437
>L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein.
Length = 606
Score = 64.1 bits (149), Expect = 7e-10
Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEG---RDQELVREM-CLNQYRHDNILPLYGYSL 233
+G G FG V++G W VAVK L+ ++ + Q EM L + RH NIL G+ +
Sbjct: 316 IGTGSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGF-M 373
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P ++ Q G SL L D Q + A+G+ +LH +IH
Sbjct: 374 TRPGFAIITQWCEGSSLYHHLHVAD--TRFDMVQLIDVARQTAQGMDYLHAKN---IIHR 428
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 429 DLKSNNIFLHEGLTVKIGDFGLA 451
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 64.1 bits (149), Expect = 7e-10
Identities = 61/211 (28%), Positives = 100/211 (47%), Gaps = 17/211 (8%)
Query: 142 AQYDKYDEIL--RKVSAIPKMSYEELRLATDDWS--ERNL-----LGRGGFGQVYKGEWK 192
A Y K+ + L R + P + LA D W +L LG+G FG+V+ G W
Sbjct: 231 AYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWN 290
Query: 193 -LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSL 250
VA+K L+ + ++E + + RH+ ++ LY P +V + M+ GSL
Sbjct: 291 GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMSKGSL 349
Query: 251 EQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKI 310
L+ + G L Q + +A G+ ++ M +H D++ ANIL+ + L K+
Sbjct: 350 LDFLKGETGKY-LRLPQLVDMAAQIASGMAYVERMN---YVHRDLRAANILVGENLVCKV 405
Query: 311 GDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
DFGLAR +E T + ++FP + A E
Sbjct: 406 ADFGLARL-IEDNEYTARQGAKFPIKWTAPE 435
>D26309-1|BAA05371.1| 647|Homo sapiens LIM kinase protein.
Length = 647
Score = 64.1 bits (149), Expect = 7e-10
Identities = 49/180 (27%), Positives = 85/180 (47%), Gaps = 12/180 (6%)
Query: 177 LLGRGGFGQVYKGEWKLLG---VAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYS 232
+LG+G FGQ K + G V + +R +E + ++E+ + H N+L G
Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVL 403
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ + + GG+L ++ D P W+QR +A G+ +LH+M +IH
Sbjct: 404 YKDKRLNFITEYIKGGTLRGIIKSMDSQYP--WSQRVSFAKDIASGMAYLHSMN---IIH 458
Query: 293 GDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNAREQWIDVTGRGNW 352
D+ N L+ + + DFGLAR DE+T + R K+P+ ++++ V G W
Sbjct: 459 RDLNSHNCLVRENKNVVVADFGLARL--MVDEKTQPEGLRSLKKPDRKKRY-TVVGNPYW 515
>BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog 1 protein.
Length = 606
Score = 64.1 bits (149), Expect = 7e-10
Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEG---RDQELVREM-CLNQYRHDNILPLYGYSL 233
+G G FG V++G W VAVK L+ ++ + Q EM L + RH NIL G+ +
Sbjct: 316 IGTGSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGF-M 373
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P ++ Q G SL L D Q + A+G+ +LH +IH
Sbjct: 374 TRPGFAIITQWCEGSSLYHHLHVAD--TRFDMVQLIDVARQTAQGMDYLHAKN---IIHR 428
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 429 DLKSNNIFLHEGLTVKIGDFGLA 451
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 64.1 bits (149), Expect = 7e-10
Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKL-----LGVAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL + VA+K L+ + R L + Q+ H NI+ L
Sbjct: 626 VVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G +V + M GSL+ LR D A + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSKPVMIVTEYMENGSLDSFLRKHD--AQFTVIQLVGMLRGIASGMKYLSDM--- 740
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 741 GYVHRDLAARNILINSNLVCKVSDFGLSR 769
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 64.1 bits (149), Expect = 7e-10
Identities = 61/211 (28%), Positives = 100/211 (47%), Gaps = 17/211 (8%)
Query: 142 AQYDKYDEIL--RKVSAIPKMSYEELRLATDDWS--ERNL-----LGRGGFGQVYKGEWK 192
A Y K+ + L R + P + LA D W +L LG+G FG+V+ G W
Sbjct: 231 AYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWN 290
Query: 193 -LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSL 250
VA+K L+ + ++E + + RH+ ++ LY P +V + M+ GSL
Sbjct: 291 GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMSKGSL 349
Query: 251 EQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKI 310
L+ + G L Q + +A G+ ++ M +H D++ ANIL+ + L K+
Sbjct: 350 LDFLKGETGKY-LRLPQLVDMAAQIASGMAYVERMN---YVHRDLRAANILVGENLVCKV 405
Query: 311 GDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
DFGLAR +E T + ++FP + A E
Sbjct: 406 ADFGLARL-IEDNEYTARQGAKFPIKWTAPE 435
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 6/142 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG G FG+V++G W VAVK L+ + +RE + RH ++ LY
Sbjct: 240 LGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLE 299
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
++ +LM GSL++ L+ D + + Q+ + VA G+ +L + IH D+
Sbjct: 300 DPIYIITELMRHGSLQEYLQ-NDTGSKIHLTQQVDMAAQVASGMAYLESRN---YIHRDL 355
Query: 296 KPANILLDQCLEPKIGDFGLAR 317
N+L+ + K+ DFGLAR
Sbjct: 356 AARNVLVGEHNIYKVADFGLAR 377
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 64.1 bits (149), Expect = 7e-10
Identities = 61/211 (28%), Positives = 100/211 (47%), Gaps = 17/211 (8%)
Query: 142 AQYDKYDEIL--RKVSAIPKMSYEELRLATDDWS--ERNL-----LGRGGFGQVYKGEWK 192
A Y K+ + L R + P + LA D W +L LG+G FG+V+ G W
Sbjct: 231 AYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWN 290
Query: 193 -LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSL 250
VA+K L+ + ++E + + RH+ ++ LY P +V + M+ GSL
Sbjct: 291 GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMSKGSL 349
Query: 251 EQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKI 310
L+ + G L Q + +A G+ ++ M +H D++ ANIL+ + L K+
Sbjct: 350 LDFLKGETGKY-LRLPQLVDMAAQIASGMAYVERMN---YVHRDLRAANILVGENLVCKV 405
Query: 311 GDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
DFGLAR +E T + ++FP + A E
Sbjct: 406 ADFGLARL-IEDNEYTARQGAKFPIKWTAPE 435
>BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein.
Length = 609
Score = 64.1 bits (149), Expect = 7e-10
Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEG---RDQELVREM-CLNQYRHDNILPLYGYSL 233
+G G FG V++G W VAVK L+ ++ + Q EM L + RH NIL G+ +
Sbjct: 319 IGTGSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGF-M 376
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P ++ Q G SL L D Q + A+G+ +LH +IH
Sbjct: 377 TRPGFAIITQWCEGSSLYHHLHVAD--TRFDMVQLIDVARQTAQGMDYLHAKN---IIHR 431
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 432 DLKSNNIFLHEGLTVKIGDFGLA 454
>BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 64.1 bits (149), Expect = 7e-10
Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLRDNEG---RDQELVREM-CLNQYRHDNILPLYGYSL 233
+G G FG V++G W VAVK L+ ++ + Q EM L + RH NIL G+ +
Sbjct: 316 IGTGSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGF-M 373
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
P ++ Q G SL L D Q + A+G+ +LH +IH
Sbjct: 374 TRPGFAIITQWCEGSSLYHHLHVAD--TRFDMVQLIDVARQTAQGMDYLHAKN---IIHR 428
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 429 DLKSNNIFLHEGLTVKIGDFGLA 451
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 6/142 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG G FG+V++G W VAVK L+ + +RE + RH ++ LY
Sbjct: 240 LGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLE 299
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
++ +LM GSL++ L+ D + + Q+ + VA G+ +L + IH D+
Sbjct: 300 DPIYIITELMRHGSLQEYLQ-NDTGSKIHLTQQVDMAAQVASGMAYLESRN---YIHRDL 355
Query: 296 KPANILLDQCLEPKIGDFGLAR 317
N+L+ + K+ DFGLAR
Sbjct: 356 AARNVLVGEHNIYKVADFGLAR 377
>AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 64.1 bits (149), Expect = 7e-10
Identities = 61/211 (28%), Positives = 100/211 (47%), Gaps = 17/211 (8%)
Query: 142 AQYDKYDEIL--RKVSAIPKMSYEELRLATDDWS--ERNL-----LGRGGFGQVYKGEWK 192
A Y K+ + L R + P + LA D W +L LG+G FG+V+ G W
Sbjct: 237 AYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWN 296
Query: 193 -LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSL 250
VA+K L+ + ++E + + RH+ ++ LY P +V + M+ GSL
Sbjct: 297 GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMSKGSL 355
Query: 251 EQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKI 310
L+ + G L Q + +A G+ ++ M +H D++ ANIL+ + L K+
Sbjct: 356 LDFLKGETGKY-LRLPQLVDMAAQIASGMAYVERMN---YVHRDLRAANILVGENLVCKV 411
Query: 311 GDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
DFGLAR +E T + ++FP + A E
Sbjct: 412 ADFGLARL-IEDNEYTARQGAKFPIKWTAPE 441
>AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 64.1 bits (149), Expect = 7e-10
Identities = 61/211 (28%), Positives = 100/211 (47%), Gaps = 17/211 (8%)
Query: 142 AQYDKYDEIL--RKVSAIPKMSYEELRLATDDWS--ERNL-----LGRGGFGQVYKGEWK 192
A Y K+ + L R + P + LA D W +L LG+G FG+V+ G W
Sbjct: 231 AYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWN 290
Query: 193 -LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGGPEACLVYQLMAGGSL 250
VA+K L+ + ++E + + RH+ ++ LY P +V + M+ GSL
Sbjct: 291 GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMSKGSL 349
Query: 251 EQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDIKPANILLDQCLEPKI 310
L+ + G L Q + +A G+ ++ M +H D++ ANIL+ + L K+
Sbjct: 350 LDFLKGETGKY-LRLPQLVDMAAQIASGMAYVERMN---YVHRDLRAANILVGENLVCKV 405
Query: 311 GDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
DFGLAR +E T + ++FP + A E
Sbjct: 406 ADFGLARL-IEDNEYTARQGAKFPIKWTAPE 435
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 64.1 bits (149), Expect = 7e-10
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 6/142 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG G FG+V++G W VAVK L+ + +RE + RH ++ LY
Sbjct: 240 LGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLE 299
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
++ +LM GSL++ L+ D + + Q+ + VA G+ +L + IH D+
Sbjct: 300 DPIYIITELMRHGSLQEYLQ-NDTGSKIHLTQQVDMAAQVASGMAYLESRN---YIHRDL 355
Query: 296 KPANILLDQCLEPKIGDFGLAR 317
N+L+ + K+ DFGLAR
Sbjct: 356 AARNVLVGEHNIYKVADFGLAR 377
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 64.1 bits (149), Expect = 7e-10
Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKL-----LGVAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL + VA+K L+ + R L + Q+ H NI+ L
Sbjct: 626 VVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRL 685
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G +V + M GSL+ LR D A + Q ++ G+A G+++L M
Sbjct: 686 EGVVTKSKPVMIVTEYMENGSLDSFLRKHD--AQFTVIQLVGMLRGIASGMKYLSDM--- 740
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 741 GYVHRDLAARNILINSNLVCKVSDFGLSR 769
>AC005057-3|AAS07438.1| 596|Homo sapiens unknown protein.
Length = 596
Score = 64.1 bits (149), Expect = 7e-10
Identities = 49/180 (27%), Positives = 85/180 (47%), Gaps = 12/180 (6%)
Query: 177 LLGRGGFGQVYKGEWKLLG---VAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYS 232
+LG+G FGQ K + G V + +R +E + ++E+ + H N+L G
Sbjct: 293 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVL 352
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ + + GG+L ++ D P W+QR +A G+ +LH+M +IH
Sbjct: 353 YKDKRLNFITEYIKGGTLRGIIKSMDSQYP--WSQRVSFAKDIASGMAYLHSMN---IIH 407
Query: 293 GDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNAREQWIDVTGRGNW 352
D+ N L+ + + DFGLAR DE+T + R K+P+ ++++ V G W
Sbjct: 408 RDLNSHNCLVRENKNVVVADFGLARL--MVDEKTQPEGLRSLKKPDRKKRY-TVVGNPYW 464
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 63.7 bits (148), Expect = 1e-09
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 8/166 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG G FG+V+ G W VA+K L+ + + E + + +HD ++ LY
Sbjct: 277 LGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + M GSL L+ +G A L + VA G+ ++ M IH D+
Sbjct: 337 P-IYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAAGMAYIERMN---YIHRDL 391
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
+ ANIL+ L KI DFGLAR +E T + ++FP + A E
Sbjct: 392 RSANILVGNGLICKIADFGLARL-IEDNEYTARQGAKFPIKWTAPE 436
>X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for raf
oncogene. ).
Length = 648
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/143 (36%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLR---DNEGRDQELVREMC-LNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L+ + Q E+ L + RH NIL GY +
Sbjct: 355 IGSGSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGY-M 412
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
+V Q G SL + L ++ Q I A+G+ +LH +IH
Sbjct: 413 TKDNLAIVTQWCEGSSLYKHLHVQE--TKFQMFQLIDIARQTAQGMDYLHAKN---IIHR 467
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 468 DMKSNNIFLHEGLTVKIGDFGLA 490
>S76617-1|AAB33265.1| 505|Homo sapiens blk protein.
Length = 505
Score = 63.7 bits (148), Expect = 1e-09
Identities = 51/168 (30%), Positives = 85/168 (50%), Gaps = 9/168 (5%)
Query: 178 LGRGGFGQVYKGEWKL-LGVAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYSLGG 235
LG G FG+V+ G +K + VA+K L++ + + E + +H+ ++ LY
Sbjct: 247 LGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVTKE 306
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + MA G L L+ +G+ LS + + +A G+ ++ M IH D+
Sbjct: 307 P-IYIVTEYMARGCLLDFLKTDEGSR-LSLPRLIDMSAQIAEGMAYIERMNS---IHRDL 361
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNAREQW 343
+ ANIL+ + L KI DFGLAR E T + ++FP + A E +
Sbjct: 362 RAANILVSEALCCKIADFGLAR--IIDSEYTAQEGAKFPIKWTAPEAY 407
>M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-syn
protooncogene mRNA, complete cds. ).
Length = 537
Score = 63.7 bits (148), Expect = 1e-09
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 8/166 (4%)
Query: 178 LGRGGFGQVYKGEWK-LLGVAVKRLRDNEGRDQELVRE-MCLNQYRHDNILPLYGYSLGG 235
LG G FG+V+ G W VA+K L+ + + E + + +HD ++ LY
Sbjct: 277 LGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + M GSL L+ +G A L + VA G+ ++ M IH D+
Sbjct: 337 P-IYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAAGMAYIERMN---YIHRDL 391
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
+ ANIL+ L KI DFGLAR +E T + ++FP + A E
Sbjct: 392 RSANILVGNGLICKIADFGLARL-IEDNEYTARQGAKFPIKWTAPE 436
>L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein.
Length = 421
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/143 (36%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLR---DNEGRDQELVREMC-LNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L+ + Q E+ L + RH NIL GY +
Sbjct: 128 IGSGSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGY-M 185
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
+V Q G SL + L ++ Q I A+G+ +LH +IH
Sbjct: 186 TKDNLAIVTQWCEGSSLYKHLHVQE--TKFQMFQLIDIARQTAQGMDYLHAKN---IIHR 240
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 241 DMKSNNIFLHEGLTVKIGDFGLA 263
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/144 (29%), Positives = 73/144 (50%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG K++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L + ++ + + GGS L P PL Q I+ + +GL +LH+ IH
Sbjct: 90 LKDTKLWIIMEYLGGGSALDLLEP----GPLDETQIATILREILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + E K+ D G+A
Sbjct: 143 RDIKAANVLLSEHGEVKLADIGVA 166
>BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related
kinase protein.
Length = 416
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/143 (36%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLR---DNEGRDQELVREMC-LNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L+ + Q E+ L + RH NIL GY +
Sbjct: 355 IGSGSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGY-M 412
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
+V Q G SL + L ++ Q I A+G+ +LH +IH
Sbjct: 413 TKDNLAIVTQWCEGSSLYKHLHVQE--TKFQMFQLIDIARQTAQGMDYLHAKN---IIHR 467
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 468 DMKSNNIFLHEGLTVKIGDFGLA 490
>AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/143 (36%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 178 LGRGGFGQVYKGEWKLLGVAVKRLR---DNEGRDQELVREMC-LNQYRHDNILPLYGYSL 233
+G G FG VYKG+W VAVK L+ + Q E+ L + RH NIL GY +
Sbjct: 355 IGSGSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGY-M 412
Query: 234 GGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHG 293
+V Q G SL + L ++ Q I A+G+ +LH +IH
Sbjct: 413 TKDNLAIVTQWCEGSSLYKHLHVQE--TKFQMFQLIDIARQTAQGMDYLHAKN---IIHR 467
Query: 294 DIKPANILLDQCLEPKIGDFGLA 316
D+K NI L + L KIGDFGLA
Sbjct: 468 DMKSNNIFLHEGLTVKIGDFGLA 490
>AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related
kinase (MST4) protein.
Length = 416
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens
cDNA FLJ90669 fis, clone PLACE1005519, moderately
similar to Homo sapiens STE20-like kinase 3 (mst-3)
mRNA. ).
Length = 392
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protein
kinase MST4a protein.
Length = 354
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4
protein.
Length = 416
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>AF156884-1|AAD39005.1| 518|Homo sapiens RIP-like kinase protein.
Length = 518
Score = 63.7 bits (148), Expect = 1e-09
Identities = 45/155 (29%), Positives = 82/155 (52%), Gaps = 11/155 (7%)
Query: 167 LATDDWSERNLLGRGGFGQVYKGEWKLLG--VAVKRLRDNEGRDQELVREMCL-NQY--R 221
++ ++ + L+G+ GFG V++ + + G VAVK + +++ +E+ L N++ R
Sbjct: 16 VSIEELENQELVGKDGFGTVFRAQHRKWGYDVAVK-IVNSKAISREVKAMASLDNEFVLR 74
Query: 222 HDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQF 281
+ ++ + P+ LV + M GSL L+ + P W CR++ V G+ +
Sbjct: 75 LEGVIEKVNWDQD-PKPALVTKFMENGSLSGLLQSQ---CPRPWPLLCRLLKEVVLGMFY 130
Query: 282 LHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLA 316
LH L+H D+KP+N+L D L K+ DFGL+
Sbjct: 131 LHDQN-PVLLHRDLKPSNVLPDPELHVKLADFGLS 164
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 63.7 bits (148), Expect = 1e-09
Identities = 59/209 (28%), Positives = 83/209 (39%), Gaps = 12/209 (5%)
Query: 119 QRATTSSDSVPLPVILFDQDTSSAQYDKYDEILRKVSAIPKMSYEELRLATDDWSERNLL 178
QR P ++L + +++ S P + + DD+ L
Sbjct: 26 QRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTI--DDFEIGRPL 83
Query: 179 GRGGFGQVYKGEWK------LLGVAVKRLRDNEGRDQELVREMCLNQY-RHDNILPLYGY 231
G+G FG VY K L V K + EG + +L RE+ + + H NIL LY Y
Sbjct: 84 GKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNY 143
Query: 232 SLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALI 291
L+ + G L + L A RIM +A L + H G +I
Sbjct: 144 FYDRRRIYLILEYAPRGMLYKELHKTCTFDEQRTATVRRIMEELADALMYCH---GKKVI 200
Query: 292 HGDIKPANILLDQCLEPKIGDFGLARKGP 320
H DIKP N+LL E KI DFG + P
Sbjct: 201 HRDIKPENLLLGLKGELKIADFGWSVHAP 229
>AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protein
kinase MASK protein.
Length = 416
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 178 LGRGGFGQVYKG----EWKLLGVAVKRLRDNEGRDQELVREMC-LNQYRHDNILPLYGYS 232
+G+G FG+V+KG +++ + + L + E +++ +E+ L+Q + YG
Sbjct: 30 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSY 89
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
L G + ++ + + GGS LR A P Q ++ + +GL +LH+ IH
Sbjct: 90 LKGSKLWIIMEYLGGGSALDLLR----AGPFDEFQIATMLKEILKGLDYLHS---EKKIH 142
Query: 293 GDIKPANILLDQCLEPKIGDFGLA 316
DIK AN+LL + + K+ DFG+A
Sbjct: 143 RDIKAANVLLSEQGDVKLADFGVA 166
>Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase
protein.
Length = 505
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/166 (30%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 178 LGRGGFGQVYKGEWKL-LGVAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYSLGG 235
LG G FG+V+ G +K + VA+K L++ + + E + +H+ ++ LY
Sbjct: 247 LGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANMMKALQHERLVRLYAVVTKE 306
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + MA G L L+ +G+ LS + + +A G+ ++ M IH D+
Sbjct: 307 P-IYIVTEYMARGCLLDFLKTDEGSR-LSLPRLIDMSAQIAEGMAYIERMNS---IHRDL 361
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
+ ANIL+ + L KI DFGLAR E T + ++FP + A E
Sbjct: 362 RAANILVSEALCCKIADFGLAR--IIDSEYTAQEGAKFPIKWTAPE 405
>Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine
protein-kinase protein.
Length = 947
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 14/135 (10%)
Query: 172 WSERNL-LGRGGFGQVYKGEWKLLGV--AVKRLRDNEGRDQELVREMCLNQYRHDNILPL 228
W+ L LGRG FG+V++ E K G AVK++R R +EL+ L R I+PL
Sbjct: 399 WATHQLRLGRGSFGEVHRMEDKQTGFQCAVKKVRLEVFRAEELMACAGLTSPR---IVPL 455
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA-RGLQFLHTMTG 287
YG GP + +L+ GGSL Q ++ + G P R G A GL++LH+
Sbjct: 456 YGAVREGPWVNIFMELLEGGSLGQLVK-EQGCLP---EDRALYYLGQALEGLEYLHS--- 508
Query: 288 SALIHGDIKPANILL 302
++HGD+K N+LL
Sbjct: 509 RRILHGDVKADNVLL 523
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine
kinase protein.
Length = 1037
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/149 (30%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H NI+ L
Sbjct: 680 VIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHL 739
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G +V + M GSL+ L+ DG + Q ++ G++ G+++L M
Sbjct: 740 EGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTV--IQLVGMLRGISAGMKYLSDM--- 794
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 795 GYVHRDLAARNILINSNLVCKVSDFGLSR 823
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/149 (30%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H NI+ L
Sbjct: 634 VIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHL 693
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G +V + M GSL+ L+ DG + Q ++ G++ G+++L M
Sbjct: 694 EGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTV--IQLVGMLRGISAGMKYLSDM--- 748
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 749 GYVHRDLAARNILINSNLVCKVSDFGLSR 777
>DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated protein
kinase kinase kinase 14 protein.
Length = 947
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 14/135 (10%)
Query: 172 WSERNL-LGRGGFGQVYKGEWKLLGV--AVKRLRDNEGRDQELVREMCLNQYRHDNILPL 228
W+ L LGRG FG+V++ E K G AVK++R R +EL+ L R I+PL
Sbjct: 399 WATHQLRLGRGSFGEVHRMEDKQTGFQCAVKKVRLEVFRAEELMACAGLTSPR---IVPL 455
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA-RGLQFLHTMTG 287
YG GP + +L+ GGSL Q ++ + G P R G A GL++LH+
Sbjct: 456 YGAVREGPWVNIFMELLEGGSLGQLVK-EQGCLP---EDRALYYLGQALEGLEYLHS--- 508
Query: 288 SALIHGDIKPANILL 302
++HGD+K N+LL
Sbjct: 509 RRILHGDVKADNVLL 523
>BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated protein
kinase kinase kinase 14 protein.
Length = 947
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 14/135 (10%)
Query: 172 WSERNL-LGRGGFGQVYKGEWKLLGV--AVKRLRDNEGRDQELVREMCLNQYRHDNILPL 228
W+ L LGRG FG+V++ E K G AVK++R R +EL+ L R I+PL
Sbjct: 399 WATHQLRLGRGSFGEVHRMEDKQTGFQCAVKKVRLEVFRAEELMACAGLTSPR---IVPL 455
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVA-RGLQFLHTMTG 287
YG GP + +L+ GGSL Q ++ + G P R G A GL++LH+
Sbjct: 456 YGAVREGPWVNIFMELLEGGSLGQLVK-EQGCLP---EDRALYYLGQALEGLEYLHS--- 508
Query: 288 SALIHGDIKPANILL 302
++HGD+K N+LL
Sbjct: 509 RRILHGDVKADNVLL 523
>BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kinase
protein.
Length = 505
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/166 (30%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 178 LGRGGFGQVYKGEWKL-LGVAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYSLGG 235
LG G FG+V+ G +K + VA+K L++ + + E + +H+ ++ LY
Sbjct: 247 LGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVTKE 306
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + MA G L L+ +G+ LS + + +A G+ ++ M IH D+
Sbjct: 307 P-IYIVTEYMARGCLLDFLKTDEGSR-LSLPRLIDMSAQIAEGMAYIERMNS---IHRDL 361
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
+ ANIL+ + L KI DFGLAR E T + ++FP + A E
Sbjct: 362 RAANILVSEALCCKIADFGLAR--IIDSEYTAQEGAKFPIKWTAPE 405
>BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for
IMAGE:4574968) protein.
Length = 599
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/166 (30%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 178 LGRGGFGQVYKGEWKL-LGVAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYSLGG 235
LG G FG+V+ G +K + VA+K L++ + + E + +H+ ++ LY
Sbjct: 247 LGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVTKE 306
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + MA G L L+ +G+ LS + + +A G+ ++ M IH D+
Sbjct: 307 P-IYIVTEYMARGCLLDFLKTDEGSR-LSLPRLIDMSAQIAEGMAYIERMNS---IHRDL 361
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
+ ANIL+ + L KI DFGLAR E T + ++FP + A E
Sbjct: 362 RAANILVSEALCCKIADFGLAR--IIDSEYTAQEGAKFPIKWTAPE 405
>BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kinase
protein.
Length = 505
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/166 (30%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 178 LGRGGFGQVYKGEWKL-LGVAVKRLRDNEGRDQELVREM-CLNQYRHDNILPLYGYSLGG 235
LG G FG+V+ G +K + VA+K L++ + + E + +H+ ++ LY
Sbjct: 247 LGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVTKE 306
Query: 236 PEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIHGDI 295
P +V + MA G L L+ +G+ LS + + +A G+ ++ M IH D+
Sbjct: 307 P-IYIVTEYMARGCLLDFLKTDEGSR-LSLPRLIDMSAQIAEGMAYIERMNS---IHRDL 361
Query: 296 KPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEPNARE 341
+ ANIL+ + L KI DFGLAR E T + ++FP + A E
Sbjct: 362 RAANILVSEALCCKIADFGLAR--IIDSEYTAQEGAKFPIKWTAPE 405
>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
isoform a variant protein.
Length = 1017
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/149 (30%), Positives = 73/149 (48%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLR---DNEGRDQELVREMCLNQYRHDNILPL 228
++G G FG+V G KL G VA+K L+ + R L + Q+ H NI+ L
Sbjct: 694 VIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHL 753
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G +V + M GSL+ L+ DG + Q ++ G++ G+++L M
Sbjct: 754 EGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTV--IQLVGMLRGISAGMKYLSDM--- 808
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++ L K+ DFGL+R
Sbjct: 809 GYVHRDLAARNILINSNLVCKVSDFGLSR 837
>AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing
kinase protein.
Length = 966
Score = 63.3 bits (147), Expect = 1e-09
Identities = 43/152 (28%), Positives = 75/152 (49%), Gaps = 17/152 (11%)
Query: 170 DDWSERNLLGRGGFGQVYKGEWKLLGVAVKRLRDNEGRDQELVREMCLNQYRHDNILPLY 229
++ SE LG G G V+ G+++ VA+K++R+ D + +R++ +H NI+
Sbjct: 166 EEISELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNETDIKHLRKL-----KHPNIIAFK 220
Query: 230 GYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAP---LSWAQRCRIMCGVARGLQFLHTMT 286
G P C++ + A G L + LR P + W+ G+A G+ +LH
Sbjct: 221 GVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWS------TGIASGMNYLHL-- 272
Query: 287 GSALIHGDIKPANILLDQCLEPKIGDFGLARK 318
+IH D+K N+L+ KI DFG +++
Sbjct: 273 -HKIIHRDLKSPNVLVTHTDAVKISDFGTSKE 303
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 62.9 bits (146), Expect = 2e-09
Identities = 46/149 (30%), Positives = 76/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNE--GRDQELVREMCL-NQYRHDNILPL 228
++G G FG+VY+G +L VA+K L+D G+ +RE + Q+ H +IL L
Sbjct: 344 VIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHL 403
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR ++ L Q ++ G+A G+ +L +
Sbjct: 404 EGVVTKRKPIMIITEFMENGALDAFLREREDQ--LVPGQLVAMLQGIASGMNYL---SNH 458
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++Q L K+ DFGL R
Sbjct: 459 NYVHRDLAARNILVNQNLCCKVSDFGLTR 487
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 62.9 bits (146), Expect = 2e-09
Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWK--LLGVAVKRLRDNEGRDQELVREMC-L 217
+Y++ + D + ++ LG G +G+VY+G WK L VAVK L+++ +E ++E +
Sbjct: 231 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM 290
Query: 218 NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVAR 277
+ +H N++ L G P ++ + M G+L LR + ++ + ++
Sbjct: 291 KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR-ECNRQEVNAVVLLYMATQISS 349
Query: 278 GLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEP 337
+++L IH D+ N L+ + K+ DFGL+R GD T ++FP +
Sbjct: 350 AMEYLEKKN---FIHRDLAARNCLVGENHLVKVADFGLSRL-MTGDTYTAHAGAKFPIKW 405
Query: 338 NARE 341
A E
Sbjct: 406 TAPE 409
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 62.9 bits (146), Expect = 2e-09
Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWK--LLGVAVKRLRDNEGRDQELVREMC-L 217
+Y++ + D + ++ LG G +G+VY+G WK L VAVK L+++ +E ++E +
Sbjct: 231 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM 290
Query: 218 NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVAR 277
+ +H N++ L G P ++ + M G+L LR + ++ + ++
Sbjct: 291 KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR-ECNRQEVNAVVLLYMATQISS 349
Query: 278 GLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEP 337
+++L IH D+ N L+ + K+ DFGL+R GD T ++FP +
Sbjct: 350 AMEYLEKKN---FIHRDLAARNCLVGENHLVKVADFGLSRL-MTGDTYTAHAGAKFPIKW 405
Query: 338 NARE 341
A E
Sbjct: 406 TAPE 409
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 62.9 bits (146), Expect = 2e-09
Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWK--LLGVAVKRLRDNEGRDQELVREMC-L 217
+Y++ + D + ++ LG G +G+VY+G WK L VAVK L+++ +E ++E +
Sbjct: 250 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM 309
Query: 218 NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVAR 277
+ +H N++ L G P ++ + M G+L LR + ++ + ++
Sbjct: 310 KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR-ECNRQEVNAVVLLYMATQISS 368
Query: 278 GLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEP 337
+++L IH D+ N L+ + K+ DFGL+R GD T ++FP +
Sbjct: 369 AMEYLEKKN---FIHRDLAARNCLVGENHLVKVADFGLSRL-MTGDTYTAHAGAKFPIKW 424
Query: 338 NARE 341
A E
Sbjct: 425 TAPE 428
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 62.9 bits (146), Expect = 2e-09
Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWK--LLGVAVKRLRDNEGRDQELVREMC-L 217
+Y++ + D + ++ LG G +G+VY+G WK L VAVK L+++ +E ++E +
Sbjct: 231 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM 290
Query: 218 NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVAR 277
+ +H N++ L G P ++ + M G+L LR + ++ + ++
Sbjct: 291 KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR-ECNRQEVNAVVLLYMATQISS 349
Query: 278 GLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEP 337
+++L IH D+ N L+ + K+ DFGL+R GD T ++FP +
Sbjct: 350 AMEYLEKKN---FIHRDLAARNCLVGENHLVKVADFGLSRL-MTGDTYTAHAGAKFPIKW 405
Query: 338 NARE 341
A E
Sbjct: 406 TAPE 409
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 62.9 bits (146), Expect = 2e-09
Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWK--LLGVAVKRLRDNEGRDQELVREMC-L 217
+Y++ + D + ++ LG G +G+VY+G WK L VAVK L+++ +E ++E +
Sbjct: 250 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM 309
Query: 218 NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVAR 277
+ +H N++ L G P ++ + M G+L LR + ++ + ++
Sbjct: 310 KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR-ECNRQEVNAVVLLYMATQISS 368
Query: 278 GLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEP 337
+++L IH D+ N L+ + K+ DFGL+R GD T ++FP +
Sbjct: 369 AMEYLEKKN---FIHRDLAARNCLVGENHLVKVADFGLSRL-MTGDTYTAHAGAKFPIKW 424
Query: 338 NARE 341
A E
Sbjct: 425 TAPE 428
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 62.9 bits (146), Expect = 2e-09
Identities = 46/149 (30%), Positives = 76/149 (51%), Gaps = 13/149 (8%)
Query: 177 LLGRGGFGQVYKGEWKLLG-----VAVKRLRDNE--GRDQELVREMCL-NQYRHDNILPL 228
++G G FG+VY+G +L VA+K L+D G+ +RE + Q+ H +IL L
Sbjct: 629 VIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHL 688
Query: 229 YGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGS 288
G ++ + M G+L+ LR ++ L Q ++ G+A G+ +L +
Sbjct: 689 EGVVTKRKPIMIITEFMENGALDAFLREREDQ--LVPGQLVAMLQGIASGMNYL---SNH 743
Query: 289 ALIHGDIKPANILLDQCLEPKIGDFGLAR 317
+H D+ NIL++Q L K+ DFGL R
Sbjct: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTR 772
>BC127603-1|AAI27604.1| 829|Homo sapiens kinase suppressor of ras 2
protein.
Length = 829
Score = 62.9 bits (146), Expect = 2e-09
Identities = 45/143 (31%), Positives = 71/143 (49%), Gaps = 11/143 (7%)
Query: 177 LLGRGGFGQVYKGEWKLLGVAVKRL---RDNEGRDQELVRE-MCLNQYRHDNILPLYGYS 232
L+G+G FGQVY G W VA++ + RDNE + + RE M Q RH+N++ G
Sbjct: 550 LIGKGRFGQVYHGRWH-GEVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGAC 608
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ P ++ L G +L +R D L + +I + +G+ +LH ++H
Sbjct: 609 MSPPHLAIITSLCKGRTLYSVVR--DAKIVLDVNKTRQIAQEIVKGMGYLH---AKGILH 663
Query: 293 GDIKPANILLDQCLEPKIGDFGL 315
D+K N+ D + I DFGL
Sbjct: 664 KDLKSKNVFYDNG-KVVITDFGL 685
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 62.9 bits (146), Expect = 2e-09
Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 161 SYEELRLATDDWSERNLLGRGGFGQVYKGEWK--LLGVAVKRLRDNEGRDQELVREMC-L 217
+Y++ + D + ++ LG G +G+VY+G WK L VAVK L+++ +E ++E +
Sbjct: 250 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM 309
Query: 218 NQYRHDNILPLYGYSLGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVAR 277
+ +H N++ L G P ++ + M G+L LR + ++ + ++
Sbjct: 310 KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR-ECNRQEVNAVVLLYMATQISS 368
Query: 278 GLQFLHTMTGSALIHGDIKPANILLDQCLEPKIGDFGLARKGPYGDERTHLKVSRFPKEP 337
+++L IH D+ N L+ + K+ DFGL+R GD T ++FP +
Sbjct: 369 AMEYLEKKN---FIHRDLAARNCLVGENHLVKVADFGLSRL-MTGDTYTAHAGAKFPIKW 424
Query: 338 NARE 341
A E
Sbjct: 425 TAPE 428
>BC107107-1|AAI07108.1| 827|Homo sapiens KSR2 protein protein.
Length = 827
Score = 62.9 bits (146), Expect = 2e-09
Identities = 45/143 (31%), Positives = 71/143 (49%), Gaps = 11/143 (7%)
Query: 177 LLGRGGFGQVYKGEWKLLGVAVKRL---RDNEGRDQELVRE-MCLNQYRHDNILPLYGYS 232
L+G+G FGQVY G W VA++ + RDNE + + RE M Q RH+N++ G
Sbjct: 548 LIGKGRFGQVYHGRWH-GEVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGAC 606
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ P ++ L G +L +R D L + +I + +G+ +LH ++H
Sbjct: 607 MSPPHLAIITSLCKGRTLYSVVR--DAKIVLDVNKTRQIAQEIVKGMGYLH---AKGILH 661
Query: 293 GDIKPANILLDQCLEPKIGDFGL 315
D+K N+ D + I DFGL
Sbjct: 662 KDLKSKNVFYDNG-KVVITDFGL 683
>BC107106-1|AAI07107.1| 827|Homo sapiens KSR2 protein protein.
Length = 827
Score = 62.9 bits (146), Expect = 2e-09
Identities = 45/143 (31%), Positives = 71/143 (49%), Gaps = 11/143 (7%)
Query: 177 LLGRGGFGQVYKGEWKLLGVAVKRL---RDNEGRDQELVRE-MCLNQYRHDNILPLYGYS 232
L+G+G FGQVY G W VA++ + RDNE + + RE M Q RH+N++ G
Sbjct: 548 LIGKGRFGQVYHGRWH-GEVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGAC 606
Query: 233 LGGPEACLVYQLMAGGSLEQRLRPKDGAAPLSWAQRCRIMCGVARGLQFLHTMTGSALIH 292
+ P ++ L G +L +R D L + +I + +G+ +LH ++H
Sbjct: 607 MSPPHLAIITSLCKGRTLYSVVR--DAKIVLDVNKTRQIAQEIVKGMGYLH---AKGILH 661
Query: 293 GDIKPANILLDQCLEPKIGDFGL 315
D+K N+ D + I DFGL
Sbjct: 662 KDLKSKNVFYDNG-KVVITDFGL 683
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.139 0.432
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 58,848,666
Number of Sequences: 224733
Number of extensions: 2592641
Number of successful extensions: 8474
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1139
Number of HSP's successfully gapped in prelim test: 1180
Number of HSP's that attempted gapping in prelim test: 5522
Number of HSP's gapped (non-prelim): 2699
length of query: 361
length of database: 73,234,838
effective HSP length: 91
effective length of query: 270
effective length of database: 52,784,135
effective search space: 14251716450
effective search space used: 14251716450
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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