BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000062-TA|BGIBMGA000062-PA|IPR002529|Fumarylacetoacetate (FAA) hydrolase (288 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A... 601 e-171 UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B... 340 2e-92 UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylace... 275 7e-73 UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-co... 256 4e-67 UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p ... 248 1e-64 UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 pr... 244 2e-63 UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; ... 229 5e-59 UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 226 4e-58 UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 222 7e-57 UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 211 1e-53 UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 208 9e-53 UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 205 1e-51 UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 204 2e-51 UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 202 6e-51 UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 201 1e-50 UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 195 9e-49 UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 195 9e-49 UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 195 1e-48 UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 195 1e-48 UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 194 2e-48 UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 192 7e-48 UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium di... 190 4e-47 UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 189 8e-47 UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 189 8e-47 UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 187 3e-46 UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 185 1e-45 UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 185 1e-45 UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family pr... 184 2e-45 UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 184 2e-45 UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 184 2e-45 UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 184 2e-45 UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; ... 183 4e-45 UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; ... 183 4e-45 UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 181 2e-44 UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 181 2e-44 UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family pr... 180 3e-44 UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase ... 180 3e-44 UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep... 180 4e-44 UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 180 4e-44 UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 180 5e-44 UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 178 2e-43 UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;... 177 3e-43 UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 177 3e-43 UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Re... 177 4e-43 UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 176 5e-43 UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 175 1e-42 UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 175 1e-42 UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 174 2e-42 UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 174 2e-42 UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 173 3e-42 UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp... 173 4e-42 UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 173 6e-42 UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 173 6e-42 UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: B... 172 8e-42 UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 172 8e-42 UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 172 1e-41 UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 171 2e-41 UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family pr... 171 2e-41 UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farci... 169 5e-41 UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctiona... 169 5e-41 UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 169 5e-41 UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 169 5e-41 UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre... 169 7e-41 UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiale... 169 9e-41 UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 169 9e-41 UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 168 1e-40 UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisom... 168 1e-40 UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family pr... 168 1e-40 UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 166 7e-40 UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomy... 166 7e-40 UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 165 9e-40 UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 165 9e-40 UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Eu... 165 9e-40 UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-D... 165 2e-39 UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase... 164 3e-39 UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family pr... 163 4e-39 UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family pr... 163 5e-39 UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;... 163 6e-39 UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family pr... 163 6e-39 UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 162 8e-39 UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 162 1e-38 UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 161 2e-38 UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaste... 161 2e-38 UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 161 2e-38 UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISO... 160 4e-38 UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;... 159 6e-38 UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 159 6e-38 UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; ... 158 2e-37 UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; ... 158 2e-37 UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 157 3e-37 UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 157 3e-37 UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; S... 157 3e-37 UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lm... 157 4e-37 UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family pr... 157 4e-37 UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 156 5e-37 UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family pr... 156 5e-37 UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 155 9e-37 UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7... 155 9e-37 UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family pr... 155 9e-37 UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 155 1e-36 UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; c... 155 2e-36 UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 154 2e-36 UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;... 153 5e-36 UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus ter... 152 9e-36 UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 152 1e-35 UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; ... 151 2e-35 UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 151 2e-35 UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584... 151 2e-35 UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 151 2e-35 UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; ... 151 3e-35 UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 150 4e-35 UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 149 8e-35 UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 149 8e-35 UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 149 1e-34 UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 147 3e-34 UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; F... 146 4e-34 UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Th... 146 6e-34 UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 146 8e-34 UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;... 145 1e-33 UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomy... 144 2e-33 UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 144 2e-33 UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 143 4e-33 UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom... 143 5e-33 UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydr... 142 7e-33 UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 142 7e-33 UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 142 9e-33 UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 140 3e-32 UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; ... 140 3e-32 UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate i... 140 5e-32 UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;... 139 9e-32 UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family pr... 138 1e-31 UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase... 138 1e-31 UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_030014... 138 2e-31 UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 138 2e-31 UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 138 2e-31 UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albic... 138 2e-31 UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 137 3e-31 UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 137 3e-31 UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family pr... 137 3e-31 UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomy... 137 3e-31 UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - P... 136 8e-31 UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family pr... 136 8e-31 UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 135 1e-30 UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 134 2e-30 UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albic... 134 2e-30 UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; ... 134 2e-30 UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 133 4e-30 UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 133 6e-30 UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 132 8e-30 UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family pr... 132 8e-30 UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 132 1e-29 UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 132 1e-29 UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 132 1e-29 UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase... 132 1e-29 UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase... 132 1e-29 UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifu... 132 1e-29 UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d... 131 2e-29 UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;... 128 2e-28 UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 128 2e-28 UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid... 127 3e-28 UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - P... 127 3e-28 UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria... 127 4e-28 UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; ... 126 7e-28 UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; E... 126 7e-28 UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; ... 126 9e-28 UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate iso... 124 2e-27 UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; E... 124 2e-27 UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 124 3e-27 UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 123 5e-27 UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 122 8e-27 UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 122 1e-26 UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 121 2e-26 UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; ... 120 6e-26 UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; ... 120 6e-26 UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 119 1e-25 UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 118 1e-25 UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d... 118 2e-25 UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 118 2e-25 UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gam... 118 2e-25 UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 116 5e-25 UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family pr... 116 7e-25 UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 116 7e-25 UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 116 9e-25 UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep... 115 2e-24 UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-co... 113 4e-24 UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family pr... 113 5e-24 UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 113 7e-24 UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family pr... 113 7e-24 UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 111 2e-23 UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 111 2e-23 UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifu... 110 5e-23 UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 110 5e-23 UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Asc... 110 5e-23 UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 109 6e-23 UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP020... 109 6e-23 UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 109 1e-22 UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 108 2e-22 UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 108 2e-22 UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family pr... 107 2e-22 UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; ... 107 3e-22 UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; ... 107 4e-22 UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 106 7e-22 UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 105 1e-21 UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 104 2e-21 UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohept... 104 2e-21 UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella per... 104 3e-21 UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Prot... 104 3e-21 UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 103 4e-21 UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|R... 103 5e-21 UniRef50_Q72P81 Cluster: Fumarylacetoacetate hydrolase family pr... 103 5e-21 UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 103 5e-21 UniRef50_A4CE53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 103 5e-21 UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:... 103 5e-21 UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 102 9e-21 UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; ... 101 2e-20 UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 100 4e-20 UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 100 4e-20 UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep... 100 5e-20 UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:... 99 6e-20 UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=... 100 9e-20 UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;... 99 1e-19 UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-h... 99 1e-19 UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family pr... 98 3e-19 UniRef50_A2CBF2 Cluster: Putative uncharacterized protein; n=1; ... 97 3e-19 UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; ... 97 6e-19 UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 95 1e-18 UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:... 95 2e-18 UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium ja... 94 3e-18 UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family pr... 94 3e-18 UniRef50_A0QS23 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 94 4e-18 UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 93 6e-18 UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 93 7e-18 UniRef50_A4F0I3 Cluster: Fumarylacetoacetate hydrolase family pr... 93 7e-18 UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; ... 92 1e-17 UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 92 1e-17 UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xan... 91 3e-17 UniRef50_Q1QDY9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 91 3e-17 UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 91 3e-17 UniRef50_Q7NUB2 Cluster: Probable isomerase; n=3; Betaproteobact... 91 4e-17 UniRef50_O86346 Cluster: POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXY... 89 9e-17 UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 89 9e-17 UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre... 89 1e-16 UniRef50_Q5P741 Cluster: Fumarylpyruvate hydrolase; n=14; Proteo... 88 3e-16 UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 88 3e-16 UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 87 5e-16 UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 87 6e-16 UniRef50_Q4WH18 Cluster: Fumarylacetoacetate hydrolase family pr... 86 9e-16 UniRef50_A4YZ43 Cluster: Putative Fumarylacetoacetate hydrolase ... 85 1e-15 UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family pr... 85 1e-15 UniRef50_Q89FA1 Cluster: Bll6800 protein; n=3; Proteobacteria|Re... 85 2e-15 UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH - P... 85 2e-15 UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 85 2e-15 UniRef50_Q8KDK4 Cluster: Fumarylacetoacetate hydrolase family pr... 85 3e-15 UniRef50_Q4AQ85 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 85 3e-15 UniRef50_Q2BPV1 Cluster: Putative uncharacterized protein; n=4; ... 83 1e-14 UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family pr... 83 1e-14 UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 83 1e-14 UniRef50_A4SV99 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 82 1e-14 UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 82 2e-14 UniRef50_Q0LGD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 80 6e-14 UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 80 6e-14 UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase fa... 79 1e-13 UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2; Ge... 79 1e-13 UniRef50_A3SNB2 Cluster: Fumarylacetoacetate hydrolase family pr... 79 1e-13 UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family pr... 79 1e-13 UniRef50_Q15XL1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 79 1e-13 UniRef50_Q3WGU5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 78 2e-13 UniRef50_A5V0Z8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 77 4e-13 UniRef50_Q44SK1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 77 7e-13 UniRef50_A3VRL8 Cluster: Putative isomerase-decarboxylase-like p... 77 7e-13 UniRef50_Q88M65 Cluster: Fumarylacetoacetate hydrolase family pr... 76 9e-13 UniRef50_Q97UR1 Cluster: 2-hydroxyhepta-2 ,4-diene-1,7-dioate is... 76 1e-12 UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 75 2e-12 UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 73 6e-12 UniRef50_Q6MNK0 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11 UniRef50_A5EF32 Cluster: Putative Fumarylacetoacetate (FAA) hydr... 72 2e-11 UniRef50_Q6F7V5 Cluster: Putative uncharacterized protein; n=2; ... 71 3e-11 UniRef50_A1UG87 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 71 3e-11 UniRef50_Q0SB97 Cluster: Possible fumarylacetoacetate hydrolase ... 71 5e-11 UniRef50_Q5B6D4 Cluster: Putative uncharacterized protein; n=1; ... 71 5e-11 UniRef50_Q0AN49 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 70 6e-11 UniRef50_A4EDA6 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 70 6e-11 UniRef50_Q7MXX3 Cluster: Fumarylacetoacetate hydrolase family pr... 69 1e-10 UniRef50_Q0S954 Cluster: Possible hydratase; n=3; Actinomycetale... 69 1e-10 UniRef50_Q6KZ97 Cluster: Fumarylacetoacetase; n=2; Thermoplasmat... 69 1e-10 UniRef50_Q395G4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 69 2e-10 UniRef50_A0VBW0 Cluster: 4-hydroxyphenylacetate degradation bifu... 69 2e-10 UniRef50_Q4D6U8 Cluster: Putative uncharacterized protein; n=2; ... 67 4e-10 UniRef50_A4QX03 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10 UniRef50_A1TDQ7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 65 2e-09 UniRef50_Q18X79 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 64 3e-09 UniRef50_Q9CKS8 Cluster: HpaG; n=1; Pasteurella multocida|Rep: H... 63 7e-09 UniRef50_Q2W964 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 63 7e-09 UniRef50_Q0HT13 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 63 7e-09 UniRef50_Q97VT9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 63 9e-09 UniRef50_Q3II31 Cluster: Putative fumarylacetoacetate hydrolase ... 62 2e-08 UniRef50_A5VED2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 61 3e-08 UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom... 61 3e-08 UniRef50_A7D1J1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 61 3e-08 UniRef50_Q7WPF0 Cluster: Putative fumarylacetoacetate hydrolase ... 61 4e-08 UniRef50_Q60C48 Cluster: Fumarylacetoacetate hydrolase family pr... 61 4e-08 UniRef50_Q7UMG2 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 60 8e-08 UniRef50_A3VNC8 Cluster: Possible isomerase/decarboxylase; n=1; ... 60 8e-08 UniRef50_Q1GRD3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 58 2e-07 UniRef50_A6C0W6 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 58 2e-07 UniRef50_Q4FWM5 Cluster: Putative uncharacterized protein; n=3; ... 57 5e-07 UniRef50_A7K1Y8 Cluster: Fumarylacetoacetate hydrolase family pr... 56 1e-06 UniRef50_Q2UV71 Cluster: Predicted protein; n=1; Aspergillus ory... 55 2e-06 UniRef50_Q8D6F8 Cluster: 2-keto-4-pentenoate hydratase; n=22; Pr... 55 2e-06 UniRef50_Q4J6K3 Cluster: 4-hydroxyphenylacetate degradation bifu... 55 2e-06 UniRef50_Q02AF6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 54 3e-06 UniRef50_A6Q508 Cluster: Fumarylacetoacetate hydrolase family pr... 53 1e-05 UniRef50_A1SUQ4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 52 1e-05 UniRef50_Q9KDZ0 Cluster: BH1071 protein; n=2; Bacillus|Rep: BH10... 51 3e-05 UniRef50_Q5KYI4 Cluster: Hypothetical conserved protein; n=3; Ba... 50 5e-05 UniRef50_A2UC21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 50 5e-05 UniRef50_Q5V2I1 Cluster: Fumarylacetoacetate hydrolase family pr... 50 5e-05 UniRef50_A6Q9W9 Cluster: Fumarylacetoacetate hydrolase; n=1; Sul... 48 3e-04 UniRef50_A7QL05 Cluster: Chromosome undetermined scaffold_116, w... 48 3e-04 UniRef50_Q1AYK9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 46 0.001 UniRef50_A6GCP0 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003 UniRef50_A3IA41 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 45 0.003 UniRef50_Q4J7I6 Cluster: Conserved protein; n=3; Thermoprotei|Re... 43 0.008 UniRef50_A0SP98 Cluster: Fumarylacetoacetate hydrolase family pr... 42 0.018 UniRef50_Q5DHL1 Cluster: SJCHGC00506 protein; n=2; Schistosoma j... 42 0.024 UniRef50_Q3E159 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 41 0.042 UniRef50_A3HUE1 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 41 0.042 UniRef50_O65374 Cluster: F12F1.8 protein; n=7; Eukaryota|Rep: F1... 40 0.074 UniRef50_Q5B250 Cluster: Putative uncharacterized protein; n=1; ... 39 0.13 UniRef50_A4CGG1 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 38 0.30 UniRef50_Q4RJI4 Cluster: Chromosome 3 SCAF15037, whole genome sh... 37 0.68 UniRef50_Q2HI94 Cluster: Putative uncharacterized protein; n=1; ... 36 0.91 UniRef50_A6RA82 Cluster: Predicted protein; n=5; Eurotiomycetida... 36 0.91 UniRef50_Q39M11 Cluster: Fumarylacetoacetase; n=17; Bacteria|Rep... 36 1.6 UniRef50_A6VYW9 Cluster: Fumarylacetoacetase; n=2; Proteobacteri... 36 1.6 UniRef50_Q10JF6 Cluster: Isomerase, putative; n=10; Magnoliophyt... 36 1.6 UniRef50_Q6MTK5 Cluster: Na+ ABC transporter, ATP-binding compon... 35 2.8 UniRef50_Q6EMI8 Cluster: Fumarylacetoacetase; n=16; Proteobacter... 34 3.7 UniRef50_A5ZTI1 Cluster: Sensor protein; n=1; Ruminococcus obeum... 34 3.7 UniRef50_A7SBM4 Cluster: Predicted protein; n=1; Nematostella ve... 34 3.7 UniRef50_A6QYE5 Cluster: Predicted protein; n=1; Ajellomyces cap... 34 3.7 UniRef50_Q64UD6 Cluster: Putative uracil permease; n=2; Bacteroi... 34 4.8 UniRef50_A7ED04 Cluster: Putative uncharacterized protein; n=1; ... 34 4.8 UniRef50_Q4HNG9 Cluster: Putative uncharacterized protein; n=1; ... 33 6.4 UniRef50_Q13GK9 Cluster: Putative fumarylacetoacetate hydrolase;... 33 6.4 UniRef50_Q54XC7 Cluster: Putative uncharacterized protein; n=1; ... 33 6.4 UniRef50_UPI0000E21965 Cluster: PREDICTED: similar to pol protei... 33 8.4 UniRef50_Q7W190 Cluster: Fumarylacetoacetase; n=9; Proteobacteri... 33 8.4 UniRef50_A7Q3E6 Cluster: Chromosome chr13 scaffold_48, whole gen... 33 8.4 UniRef50_A7KV72 Cluster: Putative metalloprotein chaperonin subu... 33 8.4 >UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A; n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase isoform A - Bombyx mori (Silk moth) Length = 330 Score = 601 bits (1485), Expect = e-171 Identities = 288/288 (100%), Positives = 288/288 (100%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA Sbjct: 43 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 102 Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI Sbjct: 103 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 162 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG Sbjct: 163 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 222 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT Sbjct: 223 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 282 Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF Sbjct: 283 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 330 >UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B; n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase isoform B - Bombyx mori (Silk moth) Length = 360 Score = 340 bits (836), Expect = 2e-92 Identities = 162/162 (100%), Positives = 162/162 (100%) Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 186 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF Sbjct: 199 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 258 Query: 187 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 246 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL Sbjct: 259 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 318 Query: 247 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF Sbjct: 319 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 360 >UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylacetoacetate hydrolase domain containing 2A isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to fumarylacetoacetate hydrolase domain containing 2A isoform 2 - Apis mellifera Length = 334 Score = 275 bits (675), Expect = 7e-73 Identities = 130/283 (45%), Positives = 190/283 (67%), Gaps = 5/283 (1%) Query: 1 MKLVQFSYKDS-PKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKST 57 M+ VQF+ K+ P+++ V ++G DI+ ++ DS +P TL + L GD L+K K++ + Sbjct: 46 MRFVQFTGKNGGPQHLGVQLVQGGDIIAVSAVDSRIPNTLKKFLEGGDDLLKKAKRIVAE 105 Query: 58 KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP 117 + IP V AP+ +DK+ C+GLNY HC+EQ ++PP P++FSKF+S IIGP Sbjct: 106 GRSVIPEVEVNFLAPVTRMDKLACVGLNYIGHCKEQGVSPPESPVIFSKFASNIIGPRDN 165 Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK-NMGQ 176 + + ++ KVDWE EL +V+G++ + + ++ GYT+AQDI+ARDWQK K N GQ Sbjct: 166 IML-PPISDKVDWEAELAIVIGKKCKALNNNEGEDYIFGYTIAQDITARDWQKSKRNGGQ 224 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 FLLGK+MDTFCPLGP V+T + + L V +NG +KQ +T++L+ ++ IS Sbjct: 225 FLLGKAMDTFCPLGPAVVTKEAISDINNLTVKTWVNGNIKQDGNTSELIFKPHEIVAYIS 284 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 MTL+PGD+ILTGTP GVG R+PPEYLQ GDVL +EI+ +G Sbjct: 285 QFMTLLPGDVILTGTPSGVGFTRKPPEYLQRGDVLETEIQGLG 327 >UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-containing protein 2B; n=41; cellular organisms|Rep: Fumarylacetoacetate hydrolase domain-containing protein 2B - Homo sapiens (Human) Length = 314 Score = 256 bits (628), Expect = 4e-67 Identities = 116/260 (44%), Positives = 175/260 (67%), Gaps = 3/260 (1%) Query: 22 GDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKSTKPATIPLSSVTLTAPIHGVDKI 79 G ++++N D +LP T+ Q L G+ L ++ + + +P S VT AP+ DK+ Sbjct: 49 GGGVINLNAFDPTLPKTMTQFLEQGEATLSVARRALAAQLPVLPWSEVTFLAPVTWPDKV 108 Query: 80 LCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVG 139 +C+G+NY DHC+EQN+ P P++FSKF+S+I+GP V + +++VDWEVEL VV+G Sbjct: 109 VCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEV-VLPPQSQEVDWEVELAVVIG 167 Query: 140 REASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEV 199 ++ ++ DA+ HVAG+TVA D+SARDW +N Q+LLGK+ DTFCPLGP ++T D V Sbjct: 168 KKGKHIKATDAMAHVAGFTVAHDVSARDWLTRRNGKQWLLGKTFDTFCPLGPALVTKDSV 227 Query: 200 GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYR 259 L++ C +NG + QSS+T Q+V L+ +S +T PGD+ILTGTP GVG++R Sbjct: 228 ADPHNLKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPPGVGVFR 287 Query: 260 QPPEYLQPGDVLTSEIEKIG 279 +PP +L+ GD + EIE++G Sbjct: 288 KPPVFLKKGDEVQCEIEELG 307 >UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p - Drosophila melanogaster (Fruit fly) Length = 293 Score = 248 bits (607), Expect = 1e-64 Identities = 128/281 (45%), Positives = 178/281 (63%), Gaps = 4/281 (1%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKAD-SSLPTTL-LQILRNGDLEKVKKLKSTK 58 M+ VQ+ K R+G L D + A +P+ L + I ++ +LE++ K + Sbjct: 6 MRFVQYLRKGDLAK-RLGLLSEDQKSLVEFAGLEGVPSDLKILIAQDPNLEELAKKAEKQ 64 Query: 59 PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPV 118 P VTL P+ KI+CIGLNY+DHC EQN P P+ FSKF++ ++GP V Sbjct: 65 PRLEVNDDVTLLPPLTDPGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQDNV 124 Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFL 178 I + K+DWEVEL V+G+ A V + A+ +V GY+VAQDISARDWQKE+N GQFL Sbjct: 125 -IAHAASSKIDWEVELVCVIGKVARQVPKSQAMDYVFGYSVAQDISARDWQKERNGGQFL 183 Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238 +GKSMDTF PLGP V+ V L + +NGV KQ+ +T L+ + +++R+S Sbjct: 184 MGKSMDTFLPLGPAVVHKSLVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQT 243 Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +TL+PGD+I+TGTP GVGM+R PPE+LQPGDV+ SEI +G Sbjct: 244 ITLLPGDIIVTGTPKGVGMHRTPPEFLQPGDVVQSEIVGLG 284 >UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 protein; n=2; Gallus gallus|Rep: PREDICTED: similar to CGI-105 protein - Gallus gallus Length = 406 Score = 244 bits (597), Expect = 2e-63 Identities = 106/218 (48%), Positives = 154/218 (70%), Gaps = 1/218 (0%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 +P + V L API +K++C+GLNY+DHC EQ++ P P++FSKF S I GP + + Sbjct: 183 LPRAGVRLLAPIDDPEKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDI-VH 241 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 + +VDWEVEL ++G+ ++E A++H+ G+TVA D+SARDWQ +N Q+LLGK Sbjct: 242 PAESSEVDWEVELAAIIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGK 301 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 + DTFCP+GP ++T D V LR+ CS+NG L QSSST QL+ +P L+ +S +TL Sbjct: 302 TFDTFCPIGPAIVTKDSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTL 361 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 PGD++LTGTP GVG++R+PP +L+PGD + EIE++G Sbjct: 362 RPGDVLLTGTPPGVGVFRKPPMFLKPGDEVQCEIEELG 399 >UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 305 Score = 229 bits (561), Expect = 5e-59 Identities = 121/293 (41%), Positives = 181/293 (61%), Gaps = 15/293 (5%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKK----LKS 56 +KLV + ++ R+G L + I+D+ AD S+P + L +K K + + Sbjct: 9 IKLVTYIPNVGEQSKRLGALLENSIIDLCSADKSIPNDMRSFLSLNSTDKWSKVINVINN 68 Query: 57 TKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ 116 IP+ + + API KI+CIGLNYK+H E + P P+VFSKF + I GP+ Sbjct: 69 INNRRIPIENCKIKAPIEP-GKIICIGLNYKEHANEAKMAIPKEPIVFSKFDNAICGPND 127 Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176 + I+ + +VD+EVEL VV+G++A V E DALQ+VAGYTV D+SARDWQ KN Q Sbjct: 128 SI-IKPVESDEVDYEVELVVVIGKQAKNVSESDALQYVAGYTVGNDVSARDWQLRKNNSQ 186 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVE--------LRVSCSLNGVLKQSSSTAQLVHSI 228 +LLGK+ DTF P+GP ++ + EV A + L + C+LNG + Q+S+T + + +I Sbjct: 187 WLLGKTFDTFAPIGPSIVINPEVAALSDDTYFDPNNLSIKCTLNGQVVQNSTTKEFIFNI 246 Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP-PEYLQPGDVLTSEIEKIGA 280 +++ +S + TL PGD+I TGTP GVG R+P P +L+ GDV+ EIE++G+ Sbjct: 247 QTVVSYLSKLFTLNPGDIIFTGTPSGVGFIRKPNPIFLKSGDVIKCEIEELGS 299 >UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase; n=1; Blastopirellula marina DSM 3645|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase - Blastopirellula marina DSM 3645 Length = 284 Score = 226 bits (553), Expect = 4e-58 Identities = 118/286 (41%), Positives = 166/286 (58%), Gaps = 6/286 (2%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60 M+LV + + P R GDD +D++ D +LPT + +L GD+ + K L + + Sbjct: 1 MRLVTYQSEAGP---RAAVARGDDFIDLHHTDHTLPTDMKSLLALGDVAREKVLAAREHG 57 Query: 61 T-IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119 IP S LT PI K++C+GLNY DH +E T P++F+KF S +I + Sbjct: 58 DPIPAGSRILT-PIINPQKVICVGLNYADHAKETGATVGDEPVIFNKFPSALIADHDEIH 116 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179 + + + +VD+E EL V +G + + +A+ HV GY DISARDWQK K Q+LL Sbjct: 117 LPPE-SSQVDYEAELVVAIGTAGKHIPQGEAMSHVGGYCCGNDISARDWQKGKPGKQWLL 175 Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239 GK+ DTF PLGP + T DE+ L + C LNG Q SST+QL+ I L+ +S+V+ Sbjct: 176 GKTFDTFAPLGPVLYTPDEIADPNNLAIRCRLNGETMQESSTSQLIFKIDFLISYLSNVV 235 Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 L PGDLI TGTP GVG+ R P +LQPGD + EIE +G R+ Sbjct: 236 MLQPGDLIFTGTPHGVGVARDPQVFLQPGDQVEVEIEGLGLLTNRV 281 >UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Planctomyces maris DSM 8797|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Planctomyces maris DSM 8797 Length = 290 Score = 222 bits (543), Expect = 7e-57 Identities = 113/261 (43%), Positives = 162/261 (62%), Gaps = 2/261 (0%) Query: 27 DINKADSSLPTTLLQILR-NGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLN 85 D++ D +LP +L IL G LE+ K + TL API K+LCIGLN Sbjct: 28 DLSAFDENLPRSLKGILAVEGGLERAKAAAEQAQQADRQITGTLLAPIPSPGKVLCIGLN 87 Query: 86 YKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCV 145 Y+DH +E + P P+ FSKFSS++ G QP+RI + V ++VD+E EL V+G+ V Sbjct: 88 YRDHAEETGMPFPDEPVCFSKFSSSVTGSGQPIRIPS-VAREVDYEAELVAVIGKTCRNV 146 Query: 146 REEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVEL 205 + +A +VAGY D+SARDWQ + GQ+LLGK+ DTF P GP ++T+DE+ A L Sbjct: 147 TQANASDYVAGYMNGHDVSARDWQIGRPGGQWLLGKTADTFAPTGPYLVTADEIKNANSL 206 Query: 206 RVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYL 265 + +LNG + Q+S+T + + +I ++ +S ++TL PGD+I TGTP GVGM R+PP YL Sbjct: 207 SIKLTLNGEVLQNSNTDKFIFTIEEVIAFVSQILTLEPGDIIFTGTPPGVGMARKPPVYL 266 Query: 266 QPGDVLTSEIEKIGAFDVRIE 286 QPGD EI+ +G +E Sbjct: 267 QPGDQACIEIQGLGMLHNTVE 287 >UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=2; Ectothiorhodospiraceae|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM 244 / SL1)) Length = 316 Score = 211 bits (516), Expect = 1e-53 Identities = 104/231 (45%), Positives = 145/231 (62%), Gaps = 9/231 (3%) Query: 62 IPLSSVTLTAPI-HGVDKILCIGLNYKDHCQEQN------LTPPPVPMVFSKFSSTIIGP 114 + ++T AP+ H ++C+GLNY DH +E L P P+VF+K ++++ GP Sbjct: 83 VTAEALTFLAPLPHPPRNVICLGLNYADHARESQQAKGDELALPEAPVVFTKATTSVAGP 142 Query: 115 DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM 174 + VT ++DWEVEL VV+GR +RE+DALQHV GYTV D+SARD Q Sbjct: 143 YDDFILDPSVTSELDWEVELAVVIGRGGRHIREQDALQHVFGYTVVNDLSARDLQFRHK- 201 Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234 QF LGKS+D CP+GP + T++ V L +SC +N +Q S T ++V SIP ++ Sbjct: 202 -QFFLGKSVDGSCPMGPWITTANAVPNPHNLALSCRINDTTEQQSHTGEMVFSIPRIIAE 260 Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 +S VMTL+PGD+I TGTP GVG R PP +LQ GD++TSE+E +G RI Sbjct: 261 LSRVMTLIPGDIIATGTPAGVGFARTPPRFLQAGDIVTSEVEGLGTLRNRI 311 >UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Pirellula sp.|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Rhodopirellula baltica Length = 342 Score = 208 bits (509), Expect = 9e-53 Identities = 102/214 (47%), Positives = 134/214 (62%), Gaps = 1/214 (0%) Query: 69 LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128 L P+ +KILCIGLNY DH E P +P+VFSKF+S ++G Q + + ++ KV Sbjct: 123 LLPPVTCPEKILCIGLNYLDHAIETGAEKPSLPVVFSKFNSALVGHGQDI-VLPKISDKV 181 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188 D+E EL VV+G+ V +A+ V GY V D+S+RDWQK + GQ+L+GKS DTF P Sbjct: 182 DYEAELVVVIGKTVRHVDANEAMDAVFGYAVGHDVSSRDWQKGRPGGQWLVGKSFDTFAP 241 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 LGP V+T+DE+ L + +NG Q S T QL+ IP+L+ +S MTL PGDLI Sbjct: 242 LGPAVVTADEISDPGNLPIRLHINGETLQESKTDQLIFDIPALIAHLSKFMTLKPGDLIF 301 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 TGTP GVG R PP YL PGD EI+ IG + Sbjct: 302 TGTPSGVGDARTPPRYLAPGDRCVVEIDGIGRLE 335 >UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=3; cellular organisms|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus halodurans Length = 319 Score = 205 bits (500), Expect = 1e-51 Identities = 119/314 (37%), Positives = 188/314 (59%), Gaps = 34/314 (10%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKA-----------------DSSLPTTLLQIL 43 MK++ + KD ++R+G + G+ ++D+N+A D+ +P L L Sbjct: 1 MKIINYRSKD---HVRIGCVIGNYVIDLNRAYAAMLEAQGLAKANEIADAVVPANSLSFL 57 Query: 44 RNGD---LEKVKKLKST-KPATIPLSS-------VTLTAPIHGVDKILCIGLNYKDHCQE 92 G+ LE K ++S K P S V API KI+C+G NY++H E Sbjct: 58 EGGEHTFLEASKAVQSIQKNELTPDQSKVFHEREVKKEAPILNSKKIICVGHNYREHILE 117 Query: 93 QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQ 152 P P++F+KF++TIIGP+ V + + +T+++D+E EL V+G++A V +EDAL Sbjct: 118 MKREIPKYPVIFAKFANTIIGPEDNVPLPS-ITEQLDYEAELAFVIGKKAKDVAKEDALD 176 Query: 153 HVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLN 212 +VAGYT+ DI+ARD Q+ Q+L GK++D P+GP ++T DE+ +L ++ S+N Sbjct: 177 YVAGYTIVNDITARDLQRRTI--QWLQGKTLDGSLPMGPWLVTKDEIPNPHQLEITLSVN 234 Query: 213 GVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLT 272 G +Q S+T LV SI L+ +S +MTL PGD++ TGTPGGVG+ R+P +LQ GDV+ Sbjct: 235 GEERQRSNTKNLVFSIQDLVVFLSGIMTLEPGDVVCTGTPGGVGVAREPQLFLQDGDVVR 294 Query: 273 SEIEKIGAFDVRIE 286 E+EK+G + R++ Sbjct: 295 IELEKVGTLENRVK 308 >UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 295 Score = 204 bits (499), Expect = 2e-51 Identities = 100/218 (45%), Positives = 142/218 (65%), Gaps = 2/218 (0%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 +PL L AP+ KI+ IGLNY+DH E P P+VF+K+++T++G + VRI Sbjct: 71 VPLEEARLHAPVLNPQKIIAIGLNYEDHANETGAPIPEKPIVFAKYANTLVGAGEEVRI- 129 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 +T + D+E EL VV+GREA V EE+AL++V GYT D+S+RD Q + GQ+ K Sbjct: 130 PPITSQADYEAELAVVIGREAKNVSEEEALEYVFGYTNCNDVSSRDLQFSEG-GQWTRSK 188 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 S+DTFCPLGP V T DE+ LR+ LNG + Q S+T++++ + L+ +S+ MTL Sbjct: 189 SLDTFCPLGPYVATRDEIPDPQSLRIRSVLNGEVMQDSNTSKMIFPVARLISFLSTGMTL 248 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 VPGD+I TGTP GVG R P +L+ GD ++ EIE +G Sbjct: 249 VPGDIIATGTPAGVGFARDPKVFLKDGDEISIEIEGLG 286 >UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Oceanobacillus iheyensis|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Oceanobacillus iheyensis Length = 301 Score = 202 bits (494), Expect = 6e-51 Identities = 113/303 (37%), Positives = 179/303 (59%), Gaps = 19/303 (6%) Query: 1 MKLVQFSYKDSPKNIRVGYL-EGDDIVDINKADS----------SLPTTLLQILRNGD-- 47 MKLV + K+S + R+G++ + +++VD++ A LP + G Sbjct: 1 MKLVSYRKKESDSSFRMGFITDNEEVVDVHLASQHAIQAGNTTIELPFQPELFYQKGQDF 60 Query: 48 LEKVKKL---KSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVF 104 +++ KL + + T L+ + L P+ K++C+G NY +H E P P++F Sbjct: 61 IDEATKLFGSSNHRDFTYSLNEIQLGMPLGTARKVICVGKNYAEHVAEMKSEIPEFPVLF 120 Query: 105 SKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDIS 164 +KF + IIGP++ + + +T+K+D+EVEL +V+GREAS V EE+AL +VAGYT+ D S Sbjct: 121 AKFDNAIIGPEEEIHY-SSLTEKLDYEVELTIVIGREASHVFEEEALDYVAGYTIGNDTS 179 Query: 165 ARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQL 224 ARD QK Q+L GKS+D P+GP V+T DE+ L ++ +N +Q S+T L Sbjct: 180 ARDLQKRTP--QWLQGKSLDHTTPIGPWVVTKDEIVDPGNLTIASYVNNEKRQYSNTKHL 237 Query: 225 VHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVR 284 + S+P L+ IS+++TL PGD+I+TGTP GVG PP Y++ D + EIE IG + Sbjct: 238 IFSVPYLVSFISNLITLKPGDIIMTGTPDGVGFAMDPPGYVKDKDKVKLEIEGIGIMENM 297 Query: 285 IEK 287 ++K Sbjct: 298 VKK 300 >UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Roseiflexus|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Roseiflexus sp. RS-1 Length = 288 Score = 201 bits (491), Expect = 1e-50 Identities = 109/293 (37%), Positives = 173/293 (59%), Gaps = 17/293 (5%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLE-KVKKLKSTKP 59 M+LV +Y+DS +++ +G L GD++V + + + +L ++ G + + + Sbjct: 1 MRLV--TYRDS-ESVHLGALRGDEVVSL----ADVAPDMLSLIDAGPAGLEAARAAVERG 53 Query: 60 ATIPLSSVTLTAPI-HGVDKILCIGLNYKDHCQE----QNLTP--PPVPMVFSKFSSTII 112 A +PLS+VTL API ++C+G+NY H E + P P P+ F+K + T+ Sbjct: 54 AGVPLSAVTLLAPIPRPRQNVICLGMNYVAHTIESYRARGREPKMPEYPVFFTKAAHTVC 113 Query: 113 GPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK 172 GPD + + VT ++D+EVEL ++G+ V ++A+++V GYT+ DISARD Q Sbjct: 114 GPDDDIPLDPKVTNELDYEVELAFIIGKAGMNVPRDEAMEYVFGYTIVNDISARDLQSRH 173 Query: 173 NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLL 232 QF GKS+ CP+GPC++T+DE+ L + LNG +Q S T L+ IP+++ Sbjct: 174 Q--QFFKGKSLYRACPMGPCIVTTDEIPNPAGLGIRLRLNGETRQDSHTGDLIFDIPAII 231 Query: 233 HRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 +S M L PG ++ TGTP GVG+ R PPEY++PGDV+ +EI+ IG RI Sbjct: 232 EHLSLGMPLEPGMIVATGTPAGVGLGRTPPEYMRPGDVMEAEIDSIGILRNRI 284 >UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=13; Proteobacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Rhodopseudomonas palustris Length = 280 Score = 195 bits (476), Expect = 9e-49 Identities = 97/211 (45%), Positives = 135/211 (63%), Gaps = 2/211 (0%) Query: 69 LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128 L +P+ G K + IGLNY DH E N+ P P+VF K +++ GP+ V TK + Sbjct: 63 LGSPVGGAPKFIAIGLNYADHAAEANMPIPAEPIVFMKAINSLCGPNDDVEKPRGSTK-L 121 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188 DWEVEL V++G A V E DAL +VAGY V D+S R++Q E+ GQ+ GKS DTF P Sbjct: 122 DWEVELAVIIGTRAKYVTEADALNYVAGYAVCNDVSERNFQLER-AGQWTKGKSHDTFGP 180 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 LGP V T DE+ +L + +NG +Q+ STA ++ ++P ++ +S +MTL+PGD+I Sbjct: 181 LGPWVATKDEIADVHKLGMWLDVNGQRRQTGSTATMIFNVPKIVSYLSELMTLMPGDIIT 240 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 TGTP GVG +PP+YL GDV+T IE +G Sbjct: 241 TGTPPGVGTGMKPPQYLNVGDVVTLGIEGLG 271 >UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 302 Score = 195 bits (476), Expect = 9e-49 Identities = 112/292 (38%), Positives = 167/292 (57%), Gaps = 22/292 (7%) Query: 7 SYKDSPKNIRVGYLEGDDIVDIN----KADSSLPTTLLQILRNGDLEKV---KKLKSTKP 59 +Y+ R+G L ++D++ LP+T+L + G + + ++S P Sbjct: 5 TYRTVETEPRLGLLHDGLVIDVDYFGDAIGQDLPSTMLDFIDLGPIGPRFLREAVESATP 64 Query: 60 A-----TIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQNLTP------PPVPMVFSKF 107 A ++P +VTL API K I IGLNY +H E P P++FSK Sbjct: 65 ADLLGTSLPQGNVTLLAPIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVIFSKP 124 Query: 108 SSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD 167 + + + P+R VT+++DWE EL V++G A V E DAL HV GYTV D+SARD Sbjct: 125 PTAVAAWNDPIRHNAKVTQQLDWETELAVIIGSTARGVAEADALNHVFGYTVINDVSARD 184 Query: 168 WQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHS 227 ++ GQ+++ K D+F P+GPC++T+DE+G L + +NGV KQ+S+T ++ + Sbjct: 185 CRRA---GQWIVSKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLFN 241 Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +P L+ I+ VMTL PGD+I TGTP GVG R P E+L PGDV+ +E IG Sbjct: 242 VPQLIADIARVMTLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIG 293 >UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Solibacter usitatus Ellin6076|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Solibacter usitatus (strain Ellin6076) Length = 269 Score = 195 bits (475), Expect = 1e-48 Identities = 91/216 (42%), Positives = 141/216 (65%), Gaps = 3/216 (1%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123 ++ + L +P+ KI+CIGLNY+DH +E + P P VF+K+ +T+ G P+ + + Sbjct: 47 VAGMKLRSPLQRPGKIICIGLNYRDHAEEAKMPIPETPTVFAKWGNTVTGHQHPIVLPKN 106 Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183 ++K D+E EL VV+G+ + E + +HV GYT+ D+SARD+Q + Q+ +GK+ Sbjct: 107 -SRKPDYEAELAVVIGKGGRHIAEANWREHVFGYTILNDVSARDFQMATS--QWTIGKTF 163 Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243 DTF P+GP ++T+DE+ LR+S +LN V Q S+T+ L+ IP L+ +SSVM+L P Sbjct: 164 DTFAPIGPWIVTTDEIEDPGALRISLTLNSVTMQDSNTSNLIFGIPKLIAYLSSVMSLEP 223 Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 GD+I TGTP GVG ++PP +L PGDV ++ IG Sbjct: 224 GDIISTGTPAGVGFAQKPPRWLVPGDVCAIQVGGIG 259 >UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Parvibaculum lavamentivorans DS-1 Length = 291 Score = 195 bits (475), Expect = 1e-48 Identities = 108/286 (37%), Positives = 165/286 (57%), Gaps = 8/286 (2%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRN-GDLEKVKKLKSTKP 59 MKL FS S +R+G + D IVD++KA LP + ++ N L + +++ + Sbjct: 1 MKLATFSEGGS---VRIGVVRDDGIVDLSKAAPELPRDMKSLIGNEAALARAREV-AKGG 56 Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119 A +PLS+V L API K+L IGLNY+DH +E P + F+K + I GP + Sbjct: 57 AALPLSAVKLLAPIPNPGKVLAIGLNYRDHVEESGQPMPEHQVWFNKQHNCITGPYADIA 116 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179 + + V+ +D+E E+C V+G+ V +E A + +AGY V D+S RDWQ N Q + Sbjct: 117 LPS-VSAFLDYEAEMCFVIGKRCKHVPKERAHEVIAGYFVGDDVSVRDWQLRTNTWQ--I 173 Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239 GKS DT P+GP ++T DEVG L + C +NG L+Q+S+T L+ + ++ Sbjct: 174 GKSFDTHGPIGPWIVTPDEVGDPHALDIKCWVNGELRQNSNTKHLIFDCFDQIAHLTQAF 233 Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 TL GD+I TGT GG+G +P + L+ GDV+ E+EK+G + R+ Sbjct: 234 TLDIGDVIFTGTSGGIGAAMKPMQLLKEGDVVRVEVEKLGYIENRV 279 >UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 293 Score = 194 bits (474), Expect = 2e-48 Identities = 106/280 (37%), Positives = 162/280 (57%), Gaps = 15/280 (5%) Query: 16 RVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKSTKPATIPLSSVTLTAPI 73 RVG + +VD++ S+ L+++ G LE+ + + + L V L API Sbjct: 12 RVGAVVDGGVVDLSGRFGSM----LELIEGGGEALEEARAVAAGSGPAARLDEVRLLAPI 67 Query: 74 HGVDK-ILCIGLNYKDHCQE-------QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVT 125 + + C+G NY H +E Q P P F K ++T+IGP + + + Sbjct: 68 PQPRRNVFCMGWNYLTHFEEGRGRREGQGEELPEYPTFFDKPTTTVIGPHDDIPFDPNFS 127 Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDT 185 +K+D+E EL VV+GR + +A+ HV GYT A D++ARD Q+ ++ GQ+L GK MD Sbjct: 128 EKIDYEAELAVVIGRSGRSIPAGEAMDHVFGYTAANDVTARDVQR-RHGGQWLKGKGMDG 186 Query: 186 FCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245 CPLGP ++T+DE+ L+V C +NGV KQ+S+T +V + L+ +S MTL+PGD Sbjct: 187 SCPLGPWIVTADEIPDVQNLQVQCRVNGVQKQNSNTRFMVFPVARLIEELSLAMTLLPGD 246 Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 ++LTGTP GVG R PPE+L+PGD +T +E +G R+ Sbjct: 247 VLLTGTPEGVGYARTPPEFLRPGDEVTVYVEGVGEISNRV 286 >UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; n=1; Pedobacter sp. BAL39|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase - Pedobacter sp. BAL39 Length = 285 Score = 192 bits (469), Expect = 7e-48 Identities = 93/211 (44%), Positives = 137/211 (64%), Gaps = 2/211 (0%) Query: 69 LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128 L +PI K++CIGLNY DH +E N PP P+VF K ++ I+GP + I + K Sbjct: 65 LGSPIGRPSKLVCIGLNYADHARETNAPLPPEPVVFMKSTTAIVGPFDQIMIPKG-SVKT 123 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188 DWEVEL +V+G++AS V E +AL +VAGY + D+S R++Q E+N G + GK DTF P Sbjct: 124 DWEVELAIVIGKKASYVEEAEALDYVAGYVLHNDVSEREFQIERN-GTWDKGKGCDTFAP 182 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 LGP + T +E+ LR+ S+NG + Q +T+ + ++P ++ +S MTL+PGD+I Sbjct: 183 LGPFLATKEEIADVNNLRLWLSVNGKMMQDGNTSNFIFNVPFVVSYVSQFMTLLPGDVIS 242 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 TGTP GVG+ +PP YL+ GDV+ I+ +G Sbjct: 243 TGTPAGVGLGFKPPVYLKAGDVVELGIDGLG 273 >UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium difficile|Rep: Putative hydrolase - Clostridium difficile (strain 630) Length = 294 Score = 190 bits (463), Expect = 4e-47 Identities = 110/290 (37%), Positives = 166/290 (57%), Gaps = 14/290 (4%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKAD-SSLPTTLLQILRN---GDLEKVKKLKS 56 MK V F + K I V E + I +IN S L T + + N GDLEK+K Sbjct: 1 MKFVTFCSSNEEK-IGVFNSETNSIYEINSLGLSKLYTDMNDFIENVSTGDLEKIKNNSF 59 Query: 57 TKPATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQE------QNLTPPPVPMVFSKFSS 109 L V L +PI K I+C+GLNYKDH E +N+ P P+ FSK + Sbjct: 60 ENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRAD 119 Query: 110 TIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ 169 IIG D + + D+ +K+D+E EL V++G+E + +EDA +++ GYT+ DIS R Q Sbjct: 120 KIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDAYEYIFGYTIVNDISERALQ 179 Query: 170 KEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIP 229 +K++ Q+ GKS+DT +GPC++ +E ++L +S +NG ++Q S+T + IP Sbjct: 180 -DKHV-QWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIP 237 Query: 230 SLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 ++++ +S MTL PGD+I TGTP GV M P YL+ GD++ ++E IG Sbjct: 238 TIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIG 287 >UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Acidobacteria bacterium Ellin345|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Acidobacteria bacterium (strain Ellin345) Length = 290 Score = 189 bits (460), Expect = 8e-47 Identities = 117/296 (39%), Positives = 172/296 (58%), Gaps = 17/296 (5%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDD-IVDINKA------DSSLPTTLLQILRNGD--LEKV 51 M+LVQ Y+ + ++ R+G + GD VD+ A D++ + L +L +G LE V Sbjct: 1 MRLVQ--YRANGES-RLGLVVGDGAFVDVASAAEKAGRDAAPFQSTLALLESGPDALEFV 57 Query: 52 KKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTI 111 + L + + L P+ KI+ IGLNY DH +E + P P+ F+KF+S++ Sbjct: 58 RTL-GVGQDVVHVDGRDLDFPV-AAKKIVAIGLNYLDHAKEAGQSIPKTPLCFAKFTSSL 115 Query: 112 IGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE 171 GP P+R+ D +VD+E EL VV+G+ A V E +A+++VAGY V D+S R Q Sbjct: 116 SGPYDPIRL-PDAEAQVDFEGELGVVIGKRAHRVAESEAMEYVAGYVVFNDVSERRSQFA 174 Query: 172 KNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSL 231 GQ+ GKS DTF P GP ++T DEV LR++ +NG + Q S+T QL+ IP L Sbjct: 175 D--GQWTRGKSCDTFSPNGPYLVTRDEVADPGNLRITTRVNGAVMQDSNTNQLIFKIPEL 232 Query: 232 LHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 + +S T PGD+I TGTP GVG R+PP YL+ GD++ EIE +G R+E+ Sbjct: 233 ISYLSHSFTFHPGDIIATGTPPGVGFSRKPPLYLREGDLVEVEIESVGRIANRVER 288 >UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Opitutaceae bacterium TAV2|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Opitutaceae bacterium TAV2 Length = 279 Score = 189 bits (460), Expect = 8e-47 Identities = 88/205 (42%), Positives = 133/205 (64%), Gaps = 1/205 (0%) Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDV-TKKVDWEVELCVV 137 ILCIGLNY+ H +E + P P++F K + + P P+ + T + + +VD+E EL VV Sbjct: 69 ILCIGLNYRRHAEETHARIPEFPVLFMKGVNALQNPGDPIMLPTHLRSDEVDYECELAVV 128 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +GR V + AL +V GYT A D+SARDWQ ++ Q+ GK+ DTF PLGP ++T D Sbjct: 129 IGRTCKNVTRDHALDYVLGYTCANDVSARDWQVKRGGSQWCRGKTFDTFAPLGPAIVTKD 188 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 E+ L++S +++G + Q +T+ ++ +P+L+ +S TL+PG +ILTGTP GVGM Sbjct: 189 EIPNPNALKISTTVSGEVLQDWTTSDMIFDVPALIEFLSGSTTLLPGTVILTGTPHGVGM 248 Query: 258 YRQPPEYLQPGDVLTSEIEKIGAFD 282 R+PP +L+ GD + EIEKIG + Sbjct: 249 ARKPPRWLRAGDKVVVEIEKIGRLE 273 >UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=6; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 291 Score = 187 bits (455), Expect = 3e-46 Identities = 103/284 (36%), Positives = 164/284 (57%), Gaps = 11/284 (3%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNG-DLEKVKKLKSTKP 59 MKL+ F + R+G L+G D++D+N+AD ++P L L G D+ + +T+ Sbjct: 1 MKLITFKQNG---DTRLGVLDGSDVIDLNRADPAVPADLRAALEAGVDVVAAARNAATRA 57 Query: 60 AT---IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ 116 IPLS V L + KI+C+G N+ DH +E P P++F + ++++I Sbjct: 58 DVGNRIPLSEVELAPVVPKPGKIVCLGHNFYDHAKEGGNLKPVYPLIFFRGATSLIAHGD 117 Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176 PV IR V++K+D+E EL VV+G+ V+ E+AL HV GY D+S RD+QK Q Sbjct: 118 PV-IRPFVSEKLDYEAELVVVIGKTGRHVKRENALDHVFGYACFNDVSVRDYQKRT--AQ 174 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVG-AAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235 + +GK+ D GP ++TSDE+ A L++ LNG Q ++TA ++ S+ + + Sbjct: 175 WTIGKNFDGTGAFGPWLVTSDELPPGAAGLKLELRLNGEAMQRANTADMIWSVAETIELL 234 Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + +TL PGD+++ GTP GVG R PP +++ GD + +IE IG Sbjct: 235 TECLTLEPGDVVVMGTPAGVGFARTPPVWMKAGDRVEVDIEGIG 278 >UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=2; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Acidovorax sp. (strain JS42) Length = 281 Score = 185 bits (451), Expect = 1e-45 Identities = 95/214 (44%), Positives = 128/214 (59%), Gaps = 5/214 (2%) Query: 59 PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPV 118 PA +P L P+ GV KI+C+GLNY DH E L P P++F K +S + GP V Sbjct: 55 PAVVP--GTRLGCPVGGVGKIVCVGLNYADHAAEAGLPAPAEPVLFMKATSALSGPTDAV 112 Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFL 178 RI K DWEVEL +V+G V E DAL HVAGY +A D+S R +Q E+ GQ+ Sbjct: 113 RIPPGALK-TDWEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERSYQMERG-GQWD 170 Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238 GK DTF P+GP ++T+DE+ + + +NG Q T + +P +L IS Sbjct: 171 KGKGCDTFAPVGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQF 230 Query: 239 MTLVPGDLILTGTPGGVGMYRQP-PEYLQPGDVL 271 MTL PGDL+LTGTP GVG+ ++P P +L+ GDV+ Sbjct: 231 MTLEPGDLVLTGTPAGVGLGQKPTPRFLRAGDVM 264 >UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=4; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Silicibacter sp. (strain TM1040) Length = 281 Score = 185 bits (450), Expect = 1e-45 Identities = 99/229 (43%), Positives = 140/229 (61%), Gaps = 6/229 (2%) Query: 54 LKSTKPATIPLSSVT--LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTI 111 L++ P ++PL T + A + V K +CIGLNY DH E ++ P P++F K +S I Sbjct: 46 LRALDPQSLPLVEGTPRIGACVGQVGKFICIGLNYADHAAESGMSLPEEPVIFFKATSAI 105 Query: 112 IGPDQPVRI-RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170 GP+ V I RT V K DWEVEL VV+G+ A + ++AL HVAGY V D+S RD+Q Sbjct: 106 CGPNDAVEIPRTSV--KTDWEVELGVVIGKTAKYIGRDEALDHVAGYCVVNDLSERDFQL 163 Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPS 230 ++ GQ++ GKS DTF P+GP ++T DEV L + +NG Q ST + + + Sbjct: 164 HRS-GQWVKGKSADTFGPIGPWLVTRDEVPDPQNLAMWLEVNGHRYQDGSTRTMHFDVAT 222 Query: 231 LLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 ++ +S M+L PGD+I TGTP GVGM + P YL+PGDV+ I +G Sbjct: 223 VISHLSQFMSLQPGDVISTGTPPGVGMGQTPETYLKPGDVMELGIAGLG 271 >UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family protein; n=8; Proteobacteria|Rep: Fumarylacetoacetate hydrolase family protein - Silicibacter pomeroyi Length = 305 Score = 184 bits (449), Expect = 2e-45 Identities = 111/299 (37%), Positives = 171/299 (57%), Gaps = 25/299 (8%) Query: 1 MKLVQFSYKDSPKNI-RVGYLEGDDIVDIN----KADSSLPTTLLQILRNGD------LE 49 MKLV +Y+DS R+G + +VD+ A +LP ++L ++ G Sbjct: 1 MKLV--TYRDSAAGEGRLGVVVDGQVVDVEWLGEAAGEALPDSMLDLIDMGPDALAAITR 58 Query: 50 KVKKLKSTKPA--TIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQ------NLTPPPV 100 + + +PA +P +V L API K I IGLNY +H E + P Sbjct: 59 ALDATNAARPAGLAVPEENVRLLAPIPRPRKNIFGIGLNYVEHVAESAKSLDTSKELPKE 118 Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160 P+VFSK +++I + ++ +T+++DWEVEL V++G+ A+ + +++A+ HV GY+V Sbjct: 119 PVVFSKPPTSVIASGEGIQHNAAMTQQLDWEVELAVIIGKRATRIAKDNAMSHVFGYSVI 178 Query: 161 QDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSS 220 D+SARD + GQ++ K DTFCP GP ++T+D+V L + + NGV KQ S+ Sbjct: 179 NDVSARD---NRRAGQWIFSKGQDTFCPFGPAIITADDVPDPHNLDLWLTKNGVEKQRSN 235 Query: 221 TAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 T L+ IP+L+ ISS +TL PGD+I TGTP GVG R P E++ PGDV+ ++ IG Sbjct: 236 TRHLLFDIPTLIADISSGITLEPGDIIATGTPAGVGAGRDPQEWMWPGDVIECGVDGIG 294 >UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; n=1; Psychroflexus torquis ATCC 700755|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase - Psychroflexus torquis ATCC 700755 Length = 251 Score = 184 bits (449), Expect = 2e-45 Identities = 91/211 (43%), Positives = 137/211 (64%), Gaps = 4/211 (1%) Query: 48 LEKVKKLKSTKPATIPL--SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFS 105 ++++ + ST + P+ + L +PI KI+C+GLNY H +E + P P++F Sbjct: 43 IKRLAEWLSTNKSNCPIIGKEIRLGSPIDRPSKIVCVGLNYAKHAKESGMEVPTEPVLFF 102 Query: 106 KFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISA 165 K SS I+GP + I ++K DWEVEL +++G +AS V+E +A+ HVAGY + DIS Sbjct: 103 KASSAIVGPYDDI-ILPKKSEKSDWEVELAIIIGDKASYVKESEAMDHVAGYVIHNDISE 161 Query: 166 RDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLV 225 R++Q E++ GQ++ GKS DTF P+GP ++T+DE+ LR+ LNG Q S+T+ L+ Sbjct: 162 REYQLERS-GQWVKGKSCDTFAPIGPFMVTTDEIDDPHNLRLWLKLNGETMQDSNTSDLI 220 Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPGGVG 256 IP L+ IS+ MTL+PGD+I TGTP GVG Sbjct: 221 FGIPKLVSYISTYMTLLPGDVISTGTPFGVG 251 >UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=6; Burkholderiales|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Burkholderia cenocepacia (strain HI2424) Length = 293 Score = 184 bits (449), Expect = 2e-45 Identities = 102/257 (39%), Positives = 156/257 (60%), Gaps = 22/257 (8%) Query: 45 NGDL-EKVKKLKSTKPATIP------LSSVTLTAPIHGVDK-ILCIGLNYKDHCQE-QNL 95 +GD+ + V++ + KP P L+ T+ API + I C+G NY +H E QN Sbjct: 35 DGDMVQLVQQFEEVKPHLKPTGNGLSLAEATILAPIDQPRRNIFCVGKNYHEHAAEFQNS 94 Query: 96 T----------PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCV 145 P P++F+K +ST+IGP + VT ++D+E EL VV+G+ + Sbjct: 95 GFDSSAKNGEHAPEAPVIFTKPASTVIGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGI 154 Query: 146 REEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVEL 205 ++ DA+ +V GYTV D +ARD QK Q+ LGKS+D FCP+GP V+TSDEV + Sbjct: 155 KKADAMNYVFGYTVINDFTARDLQKLHR--QWFLGKSLDGFCPMGPFVITSDEVNGQ-NI 211 Query: 206 RVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYL 265 + C +NG L+Q+S+T++L+ IP+L+ +S+ + L PGD+I TGTP GVG+ PP++L Sbjct: 212 DIKCWVNGELRQNSNTSKLIFDIPTLIETLSAGIELQPGDVIATGTPAGVGIGFNPPKFL 271 Query: 266 QPGDVLTSEIEKIGAFD 282 Q GDV+ EI+ +G + Sbjct: 272 QKGDVIRIEIQNVGVLE 288 >UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=2; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 287 Score = 184 bits (448), Expect = 2e-45 Identities = 106/293 (36%), Positives = 166/293 (56%), Gaps = 17/293 (5%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60 M++ + + + +++ V +G + +N A T L ++ GD +K+ L+S Sbjct: 1 MRIATYQW-NGQRHVGVVSEDGRSLTPVNLAPGQADTGALAVIALGDPKKLP-LRSE--- 55 Query: 61 TIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQE--------QNLTPPPVPMVFSKFSSTI 111 ++ L V L API + I C+G NY H +E + P P+VF+K + Sbjct: 56 SVSLHDVKLEAPIPLPRRNIFCVGRNYHAHAKELSASVFKDNSANPASWPIVFTKVPECV 115 Query: 112 IGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE 171 +GP V + T V++++D+E EL +V+G + A+QHV GYT+ D++ARD Q Sbjct: 116 VGPTDDVMLPTGVSEEIDYESELAIVIGTGGRNISRAAAMQHVFGYTIINDVTARDVQMR 175 Query: 172 KNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSL 231 Q+ LGKS DTFCP+GP ++T+DE+ + RV +NG L+Q + T L+ IP+L Sbjct: 176 HQ--QWDLGKSFDTFCPMGPWIVTADELDGS-RTRVRGWVNGELRQDAQTTDLIFDIPAL 232 Query: 232 LHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVR 284 + S +TL PGD+I TGT GVGM +PP+YL+ GDV+ EI+ IGA + R Sbjct: 233 IETCSRGITLYPGDVIATGTAAGVGMGMKPPQYLKAGDVVRIEIDGIGAIENR 285 >UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; Bordetella|Rep: Putative uncharacterized protein - Bordetella parapertussis Length = 294 Score = 183 bits (446), Expect = 4e-45 Identities = 103/295 (34%), Positives = 164/295 (55%), Gaps = 18/295 (6%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDD-IVDINKADSSLPTTLLQILRNGDLE-KVKKLKSTK 58 MK + F D ++ G + G D +VD+ A LP L + R+G L V +L + Sbjct: 1 MKYISFELPDGRRH--AGVMTGPDTLVDLTDA-MDLPDLLTLLQRHGQLAGDVARLAAQA 57 Query: 59 PATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQNLTP----------PPVPMVFSKF 107 T+ L +V + AP+ + + C+G NY +H +E + P P++FSK Sbjct: 58 RHTVALDAVRVLAPLPNPPRNVFCVGKNYHEHAREFARSGFDSSAAAGAVPAAPIIFSKP 117 Query: 108 SSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD 167 S++ GP + D VD+E EL VV+G+ ++D V GYT+ D+++R Sbjct: 118 PSSVSGPGDAIDTALDPCDSVDYEAELAVVIGKAGRVAPDDDPWSFVFGYTLVNDVTSRG 177 Query: 168 WQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHS 227 QK + Q+LLGK +D +CP+GP ++++DE+G L ++C +NG L+QS+ + L+ Sbjct: 178 LQKRHS--QWLLGKGIDGYCPMGPALVSADEIGDIGALEITCEVNGELRQSARLSDLIFD 235 Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 IP+L+ I + +TL PGD+I TGTP GVG+ PP+YL+ GDV+ E IG + Sbjct: 236 IPTLVRAIGASITLQPGDVIATGTPVGVGIGFTPPKYLRRGDVVRVRAEPIGVLE 290 >UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; Clostridium kluyveri DSM 555|Rep: Putative uncharacterized protein - Clostridium kluyveri DSM 555 Length = 301 Score = 183 bits (446), Expect = 4e-45 Identities = 104/296 (35%), Positives = 169/296 (57%), Gaps = 21/296 (7%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINK-----ADSSLPTTLLQILRNGDLEKVKK-- 53 MK V + YK +G L+ I++ + + P ++++++ D +K+ + Sbjct: 1 MKFVTYDYKGKEN---IGILKDKSILNFESIFYEIGEENPPKDMVELIKYLDEDKLNEVE 57 Query: 54 --LKSTKPATIPLSSVTLTAPI-HGVDKILCIGLNYKDHCQEQNLTP------PPVPMVF 104 LKS + L +V L API + + C+G NY++H +E LT P VP+ F Sbjct: 58 EFLKSKSLQGVFLDTVKLKAPIPYPKRNVFCLGKNYEEHAREIKLTRITGNEIPKVPIYF 117 Query: 105 SKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDIS 164 +K +S IG + ++VT +VD+EVEL VV+G+ +++E+A +++ GYT+ DIS Sbjct: 118 TKVASPAIGNGDSIEFSSEVTNQVDYEVELGVVIGKNGKNIKKEEAEKYIFGYTIINDIS 177 Query: 165 ARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQL 224 ARD Q Q+ GKS+DTFCP+GPC++ +E+ + L + C +N L+Q S+T L Sbjct: 178 ARDLQGSHI--QWFKGKSLDTFCPMGPCIVHKNEIPFPINLDIKCWVNEELRQDSNTKNL 235 Query: 225 VHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280 + IP ++ +S ++L GD+I TGTP GVGM P + L+ GD + IEKIG+ Sbjct: 236 IFDIPYIISDLSKGVSLKAGDIIATGTPSGVGMGFSPIKVLKQGDSIECYIEKIGS 291 >UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Bacillus clausii KSM-K16|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Bacillus clausii (strain KSM-K16) Length = 292 Score = 181 bits (441), Expect = 2e-44 Identities = 91/231 (39%), Positives = 141/231 (61%), Gaps = 5/231 (2%) Query: 51 VKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSST 110 ++ L+ T P + S T I +KI+CIGLNY+ H E P P++FSKF++T Sbjct: 55 MQTLEQTGPYMHAIESCTFGPAIPNPEKIICIGLNYRRHADETGSPYPETPILFSKFNNT 114 Query: 111 IIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170 + G + + VT+ +D+EVEL +V+G+ A V E++AL +V GY A D+SARD Q Sbjct: 115 LTGHGSNIVV-PPVTQALDYEVELAIVIGKTAKQVTEDEALNYVLGYCTANDLSARDLQM 173 Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPS 230 + Q+LLGK+ D FCP+GP ++T +++ L + +NG +KQ S+TA ++ + Sbjct: 174 KT--AQWLLGKTCDGFCPIGPFLVTKEDIADPQNLALETRVNGEIKQQSNTADMIFTCAE 231 Query: 231 LLHRISSVMTLVPGDLILTGTPGGV--GMYRQPPEYLQPGDVLTSEIEKIG 279 ++ +S TL PGD++LTGTP GV G+ YLQPGD ++ IE++G Sbjct: 232 IISYVSRHFTLKPGDILLTGTPEGVILGLPEAERRYLQPGDTVSVHIEQLG 282 >UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 233 Score = 181 bits (441), Expect = 2e-44 Identities = 95/201 (47%), Positives = 121/201 (60%), Gaps = 2/201 (0%) Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138 I + LNY D E P VP +F K SS++IG P+ + T VT+ VDWE EL VV+ Sbjct: 16 IFGVALNYVDSIAEMGFERPTVPFLFPKLSSSVIGDGDPIVVDTTVTRFVDWETELAVVI 75 Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE 198 G EA V +AL+ V GYTVA DISARD GQ+L GK +DTFCPLG V+ + E Sbjct: 76 GTEARNVPAAEALEVVYGYTVANDISARDLLTAD--GQWLRGKGLDTFCPLGHVVVPAAE 133 Query: 199 VGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMY 258 + L V LNG + Q +TA +V + L+ +S TL PGD+ILTGTP G G + Sbjct: 134 IPDPQALAVRTWLNGEIVQDGTTADMVFGVGELISYLSRFFTLRPGDVILTGTPAGCGAF 193 Query: 259 RQPPEYLQPGDVLTSEIEKIG 279 PP L+PGDV+ SE+E IG Sbjct: 194 MDPPRGLRPGDVVESEVEGIG 214 >UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family protein; n=21; Firmicutes|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus anthracis Length = 302 Score = 180 bits (439), Expect = 3e-44 Identities = 96/256 (37%), Positives = 150/256 (58%), Gaps = 12/256 (4%) Query: 34 SLPTTLLQILRNGD--LEKVKKL-----KSTKPATIPLSSVTLTAPIHGVDK-ILCIGLN 85 ++P T+L+ + G EK+ + ++ A PL+ V + API K ILC+G N Sbjct: 42 TIPITMLECIERGTECFEKICDIVNWAKENGGTAYYPLTEVKILAPIPRPRKNILCVGKN 101 Query: 86 YKDHCQEQNLTP--PPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREAS 143 Y++H E P M+F+K +T+IG D+ + T ++D+E EL +V+G+ Sbjct: 102 YREHAIEMGGVESIPENIMIFTKAPTTVIGMDEKINSHPHATNELDYEGELAIVIGKRGK 161 Query: 144 CVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAV 203 +++E AL+HV GYT+ DI+ARD Q++ QF LGKS DTFCP+GP ++ + Sbjct: 162 QIKKEKALEHVFGYTIINDITARDIQRKHK--QFFLGKSFDTFCPMGPYLIHKSMISTPN 219 Query: 204 ELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPE 263 L + +NG ++Q+S+T +++ SI ++ IS MTL PGD+I TGTP GVG PP+ Sbjct: 220 ALHIETIVNGEVRQTSNTNKMIFSIEEIISTISKGMTLEPGDIIATGTPAGVGKGFTPPK 279 Query: 264 YLQPGDVLTSEIEKIG 279 +L GD + +E IG Sbjct: 280 FLHAGDEVVITVEGIG 295 >UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase family protein; n=2; Arthrobacter|Rep: Putative fumarylacetoacetate hydrolase family protein - Arthrobacter nitroguajacolicus Length = 299 Score = 180 bits (439), Expect = 3e-44 Identities = 102/247 (41%), Positives = 138/247 (55%), Gaps = 9/247 (3%) Query: 42 ILRNGDLEKVKKLKSTKPA-TIPL--SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP 98 ++ NG E + S + A +PL + L + K++C GLNY DH QE P Sbjct: 36 LMDNGWREVAEDAASGRKAGAVPLHGAQADLAPLLPAAAKVICCGLNYGDHIQEMGRALP 95 Query: 99 PVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYT 158 P +F+K++ T++G P+ + + KVDWE EL VV+G V E+ AL +AGYT Sbjct: 96 DYPTLFAKYADTLVGASDPIYVHG--SDKVDWEAELAVVIGSNLYRVDEDQALAGIAGYT 153 Query: 159 VAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQS 218 VA D+S RDWQ Q+ GK+ D PLGP +LT+DE A + V +NG Q Sbjct: 154 VANDVSMRDWQNRTL--QWFQGKAFDATTPLGPVMLTADE--APADFDVYGYVNGEQVQK 209 Query: 219 SSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278 +T+ LV L+ IS L PGD++LTGTPGGVGM PP +L GDVLT+EI I Sbjct: 210 GNTSTLVFGPARLVAYISQFTMLRPGDVVLTGTPGGVGMGMNPPRFLSDGDVLTTEIPGI 269 Query: 279 GAFDVRI 285 G + RI Sbjct: 270 GRLENRI 276 >UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep: Putative oxygenase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 287 Score = 180 bits (438), Expect = 4e-44 Identities = 99/263 (37%), Positives = 146/263 (55%), Gaps = 6/263 (2%) Query: 18 GYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPAT-IPLSSVTLTAPIHGV 76 G + G+ I+D+ A PT + R+G +L+ A + L+ TL API Sbjct: 19 GAVVGERIIDL--ATPQAPTLRAALARDGVDGLAARLRQADGAAGLALADATLLAPITDP 76 Query: 77 DKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCV 136 DKILCIGLNY+ H +E + P P F +F+ ++ QPV +R + + D+E EL V Sbjct: 77 DKILCIGLNYRLHAEEAGMAIPARPSTFVRFAGSLAAQGQPV-LRPAESDQFDYEAELAV 135 Query: 137 VVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTS 196 ++G+ A V + A++HVAGY + S RDWQ+ Q GK+ GP ++T+ Sbjct: 136 IIGKPARRVSQARAMEHVAGYACLAENSVRDWQRHST--QATPGKNFVRSGAFGPWLVTA 193 Query: 197 DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVG 256 DE GA + V LNG Q S A ++ ++ L+ +S+ L+PGD+I TGTP GVG Sbjct: 194 DEAGAPEAMTVIGRLNGETVQHDSVANMIFTVAQLVSYLSTFAELLPGDVIATGTPAGVG 253 Query: 257 MYRQPPEYLQPGDVLTSEIEKIG 279 M R+PP YL+PGDV +I +G Sbjct: 254 MSRKPPRYLRPGDVFEVDISGVG 276 >UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Symbiobacterium thermophilum|Rep: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Symbiobacterium thermophilum Length = 254 Score = 180 bits (438), Expect = 4e-44 Identities = 98/219 (44%), Positives = 128/219 (58%), Gaps = 11/219 (5%) Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 T+PL +V L AP+ KI+CIG NY+DH E P PM F K S +IGP + +R+ Sbjct: 40 TVPLQAVQLLAPVTP-SKIVCIGRNYRDHAAELGNAAPERPMFFLKAPSALIGPGEAIRL 98 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 D V WE EL VV+GR V DAL +V GYT+A D+S RD QK F G Sbjct: 99 -PDPDATVHWEAELAVVIGRRMKDVAPADALSYVFGYTIANDVSHRDAQKADGAFGFGRG 157 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 KS DTFCP GP V+T A + ++C N ++QS ST ++H +P LL +S +MT Sbjct: 158 KSYDTFCPCGPAVVTEGIDPADALITLTC--NEEVRQSDSTGLMIHPVPELLSYLSQIMT 215 Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 L+PGDL+LTGTP GVG ++PGD++ I IG Sbjct: 216 LMPGDLVLTGTPKGVGA-------MKPGDLIEIHIPGIG 247 >UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=3; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Neptuniibacter caesariensis Length = 286 Score = 180 bits (437), Expect = 5e-44 Identities = 93/218 (42%), Positives = 135/218 (61%), Gaps = 4/218 (1%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 IPL+ V+L AP+ K L +GLNY DH +E L P P F+K SS +IGP++ + R Sbjct: 58 IPLNEVSLLAPVASPQKFLGVGLNYADHIEETGLDTPEFPTFFNKQSSCVIGPNEAIH-R 116 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 V++K+D+E EL +V+G+ V E A + +AG+T+ D+S RDWQ + + LGK Sbjct: 117 PTVSEKLDYEGELAIVIGKACRHVPYEKASEVIAGFTIVNDVSVRDWQIKSPT--WTLGK 174 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 S DT P+GP ++T+DEV L + +N L+Q S+T L+ L+ +S+V TL Sbjct: 175 SFDTHGPMGPWIVTADEVNPH-NLELKTWVNDELRQHSNTKHLIFDCYQLIETLSTVCTL 233 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 PGD+I TGT GVG+ +P Y++PGD +T EIE IG Sbjct: 234 QPGDVIATGTSSGVGVKMKPRGYMKPGDRVTIEIEGIG 271 >UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Clostridiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase - Alkaliphilus metalliredigens QYMF Length = 300 Score = 178 bits (433), Expect = 2e-43 Identities = 99/303 (32%), Positives = 175/303 (57%), Gaps = 20/303 (6%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDD--IVDINKADSSL----PTTLLQILRNGDLEKVKKL 54 MK + F+ KD +N R+G + + ++D+N S L++ ++ D++ +K++ Sbjct: 1 MKFIAFTTKDK-ENTRLGVYKNSESIVIDLNTIGLSRFFHDMNDLIKNIKPKDIDVLKEV 59 Query: 55 KST----KPATIPLSSVTLTAPI-HGVDKILCIGLNYKDHCQE------QNLTPPPVPMV 103 S + T + +TL API + ++C+GLNY +H E +N+ P + Sbjct: 60 ISLVEEKEYETYHVEEITLGAPIDRTIHDVICVGLNYAEHIDETKKGFDENMEIPLHTVY 119 Query: 104 FSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDI 163 FSK ++ + GP + + + + + +D+EVEL V++G+E + +E+A +++ GYT+ D+ Sbjct: 120 FSKRANQVKGPGEEIESHSHLNESMDYEVELAVIIGKEGINISKEEAKEYIFGYTILNDL 179 Query: 164 SARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQ 223 SAR QK N Q+ GKS+D F +GPC++ VG +EL + +N L+Q+S+T Sbjct: 180 SARGLQK--NHVQWFRGKSLDGFTSMGPCIVHGSSVGFPLELDIKSRVNDELRQNSNTKF 237 Query: 224 LVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDV 283 ++ + +++ IS MTL+PGD+I TGTP GVGM PP +L+ GD + EI+ +G Sbjct: 238 MMKDVSTIISEISQGMTLLPGDVIATGTPSGVGMGFTPPRFLKAGDTVECEIQHMGLLKN 297 Query: 284 RIE 286 +I+ Sbjct: 298 KIK 300 >UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative fumarylacetoacetate hydrolase - Aurantimonas sp. SI85-9A1 Length = 293 Score = 177 bits (431), Expect = 3e-43 Identities = 105/296 (35%), Positives = 168/296 (56%), Gaps = 22/296 (7%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60 MKL+ F P G L+G++IV ++ ++ + GD E + K TK A Sbjct: 1 MKLLTFERDGVPG---AGLLDGNEIVVCETGAAA--RLAVRRIAEGDAELLDAWK-TKAA 54 Query: 61 T----IPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQNLTP---------PPVPMVFSK 106 + S VT+ AP+ + I C+G NY++H E + + P P++F+K Sbjct: 55 NGAERLSRSEVTILAPLPETRRDIFCVGKNYREHASEFHNSGFDSGGKQAIPVAPVIFTK 114 Query: 107 FSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISAR 166 S IIGP + D T+ VD+E EL VV+G+ A V + DA+ +V GY V D+++R Sbjct: 115 SLSAIIGPGATIEAGLDRTRTVDYEGELGVVIGKRAFGVTKADAMDYVFGYVVINDVTSR 174 Query: 167 DWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVH 226 + Q+ + Q+++GK +DTF P+GP ++T+DEV +L V+ ++NG +Q +S A L+ Sbjct: 175 ELQRHHS--QWVIGKGIDTFAPMGPVLVTADEVPDVTKLTVTTTVNGETRQKASVAGLIF 232 Query: 227 SIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 IP+L+ +++ MTL+PGD+I TGTP GVG+ PP YL GD + I+ +G + Sbjct: 233 DIPTLIETMTATMTLLPGDIIATGTPAGVGIGFDPPRYLADGDRVAVTIDGLGTLE 288 >UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Alkaliphilus metalliredigens QYMF|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Alkaliphilus metalliredigens QYMF Length = 298 Score = 177 bits (431), Expect = 3e-43 Identities = 90/244 (36%), Positives = 142/244 (58%), Gaps = 9/244 (3%) Query: 43 LRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQN------L 95 LR E + K + + V + API + + ++C+GLNYK H E + Sbjct: 50 LREVAKEVIDNKKLWQEQGTDIYKVKVIAPIPRLKRNVICLGLNYKAHVAESQSALSAGI 109 Query: 96 TPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVA 155 P P+ F+K S+ IGP + + +T++VD+EVEL V++G+ + + E+ H+ Sbjct: 110 KMPEFPVYFTKMSTQAIGPQEAINSHPQITQEVDYEVELAVIIGKGGTNIPPEEVQDHIF 169 Query: 156 GYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVL 215 GYT+ D+SARD Q+ N Q++ GKS+DTF +GP ++ + + VEL + +NG + Sbjct: 170 GYTILNDVSARDLQRRHN--QWVKGKSLDTFTVMGPWIMEKETISLPVELDLYSKVNGEI 227 Query: 216 KQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275 +Q S+T + IP+++ +S +TL GD+I TGTP GVGM PP+YL+ GDV+ I Sbjct: 228 RQHSNTKDFIFDIPTVISELSKGLTLEAGDVIATGTPAGVGMGFNPPKYLKAGDVVECYI 287 Query: 276 EKIG 279 EKIG Sbjct: 288 EKIG 291 >UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Rep: Blr5285 protein - Bradyrhizobium japonicum Length = 283 Score = 177 bits (430), Expect = 4e-43 Identities = 101/279 (36%), Positives = 157/279 (56%), Gaps = 7/279 (2%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60 MKL+ F DS + G ++ + +VD+ + TTL Q+L G + + KL ++ Sbjct: 1 MKLLSFIV-DSRTSF--GAVKDNGVVDLGARMAGC-TTLRQLLEAGRVAEAAKLVASAAP 56 Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 L V+ I KI+C+GLNY+DH E P +F +F + +G QP+ + Sbjct: 57 DHALDKVSFAPVIPDPGKIICVGLNYRDHVAETGRIVTEKPALFVRFPCSQVGHLQPI-V 115 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 + V+ D+E EL +V+G+E + AL H+AGY+ + S RDWQ+ + QFL G Sbjct: 116 KPKVSDDFDYEGELALVIGKEGRHIPANRALDHIAGYSCYNEGSVRDWQRHTS--QFLSG 173 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 K+ GP ++T+DE+ +L + LNG + Q ++T L+ +IP L+ IS++ Sbjct: 174 KTFAESGSFGPWLVTADEIPDPSKLTLQTRLNGTVVQDTTTDLLITAIPGLIAYISTICP 233 Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 LVPGD+I+TGTPGGVG R PP +++PGD + EI IG Sbjct: 234 LVPGDVIVTGTPGGVGAKRTPPLWMRPGDTVEVEISGIG 272 >UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Symbiobacterium thermophilum|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Symbiobacterium thermophilum Length = 294 Score = 176 bits (429), Expect = 5e-43 Identities = 90/224 (40%), Positives = 134/224 (59%), Gaps = 3/224 (1%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 +P + L P+ KILC+GLNY+ H E ++ P P++F+KF + + GP PV + Sbjct: 70 LPEDGLRLGPPVPRPGKILCVGLNYRAHAAEAHMAVPAYPVLFAKFQNAVAGPGDPV-VL 128 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 + ++ D+E EL VV+GR A V E AL +V GY D+SAR+ Q + Q+LLGK Sbjct: 129 PSIAEQYDYEAELVVVIGRRARRVPAEAALDYVLGYCNGNDLSARELQMRTS--QWLLGK 186 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 S+D F P+GP ++T DEV +LR+ NG ++Q T ++ + L+ IS MTL Sbjct: 187 SLDGFLPIGPYLVTRDEVPDPQDLRIRLWRNGEIRQDGHTRNMLFPVAELIAYISRYMTL 246 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 PGD+I TGTP GV M ++L+PGDV+ EI+ +G + R+ Sbjct: 247 EPGDIIATGTPEGVIMGLAEKDWLKPGDVVAVEIDGLGRLENRL 290 >UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Dinoroseobacter shibae DFL 12 Length = 308 Score = 175 bits (426), Expect = 1e-42 Identities = 94/231 (40%), Positives = 142/231 (61%), Gaps = 9/231 (3%) Query: 56 STKPATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQE----QN--LTPPPVPMVFSKFS 108 S + A I L + L AP+H K I C+G NY +H E QN + P+ F+K + Sbjct: 71 SYRDARISLDNPFL-APLHTPRKNIFCVGRNYAEHIAEGERAQNAKIGITEHPVYFTKPA 129 Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168 + ++G V I V++K+D+EVEL VV+G + ++ A HV GYT+ DI+ARD Sbjct: 130 TAVVGHGGDVLIFPSVSEKIDYEVELAVVIGTTGRDIPKDRAFAHVFGYTILNDITARDV 189 Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSI 228 Q+ ++ GQ+ GKS+D CP+GP ++T+DE+ +L +S S+NG L+Q+ T ++ I Sbjct: 190 QR-RHGGQYFKGKSLDGSCPIGPWIVTADEITDPQDLSISLSVNGELRQNGWTHDMIFDI 248 Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 P+L+ +S +TL PGD+I TGTP GVG PP+YL+PGD + +I IG Sbjct: 249 PTLIASLSEGLTLEPGDIIATGTPSGVGYAMDPPQYLKPGDTVICDIANIG 299 >UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=9; Proteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Burkholderia cenocepacia PC184 Length = 306 Score = 175 bits (425), Expect = 1e-42 Identities = 94/250 (37%), Positives = 148/250 (59%), Gaps = 6/250 (2%) Query: 32 DSSLPTTLLQILRNG-DLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHC 90 D++ P L +L G DL +V + + + L +V + P +KILC+GLNY DH Sbjct: 45 DTAYPGDLDSLLAQGADLAEVAA-RLARGTPVDLDAVRVLPPFGRPNKILCVGLNYLDHS 103 Query: 91 QEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDA 150 E P VF++F+S++IG DQP+ + + ++D+E EL V+G+ + E A Sbjct: 104 METGFAKQTYPTVFARFASSLIGHDQPIALPAQ-SSQLDYEGELVAVIGKAGRGITRERA 162 Query: 151 LQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVE-LRVSC 209 L HVAGY++ D++ RD+Q Q+ +GK+ D GP +T+DE+ + LR+ Sbjct: 163 LDHVAGYSLFNDVTLRDYQFRTP--QWTMGKNFDGTGGFGPWFVTADELPRGCKGLRIQT 220 Query: 210 SLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGD 269 LNG + Q +ST+ ++ I +L+ +S VMTL GDLI+TGTP G+GM R+P +++ GD Sbjct: 221 RLNGAVVQEASTSDMIFDIETLVVMLSEVMTLQAGDLIVTGTPAGIGMAREPQLWMKAGD 280 Query: 270 VLTSEIEKIG 279 V EIE++G Sbjct: 281 VCEVEIEQLG 290 >UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=2; Proteobacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Fulvimarina pelagi HTCC2506 Length = 337 Score = 174 bits (423), Expect = 2e-42 Identities = 95/231 (41%), Positives = 135/231 (58%), Gaps = 4/231 (1%) Query: 51 VKKLKSTKPATIPL--SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFS 108 +K+L + P ++P S L API V + IGLNY DH E P P+VFSK Sbjct: 97 LKRLAAIDPKSLPKIDPSHRLGAPIARVGHFIAIGLNYADHAAETGADLPVEPLVFSKAP 156 Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168 S+I GP + I TK +DWEVEL VV+G A + E +A+ HVAG+ + D+S R + Sbjct: 157 SSICGPHDELPIPPGSTK-LDWEVELAVVIGERAYNINETEAMNHVAGFCLCNDVSERAF 215 Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSI 228 QKE+ GQF+ GKS LGP ++T D +G +L + S+NG ++Q +T ++ S Sbjct: 216 QKERG-GQFIKGKSSPRTGALGPWLVTPDRLGDPQQLDLWLSVNGEIRQRGTTRDMLFSA 274 Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 ++ +S M L PGD+I TGTP GVG PP++L+ GD+LT I +G Sbjct: 275 AFIVSYLSKFMILEPGDVITTGTPSGVGAGMTPPQFLREGDILTLGIGGLG 325 >UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=5; Thermoprotei|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Pyrobaculum islandicum (strain DSM 4184 / JCM 9189) Length = 310 Score = 174 bits (423), Expect = 2e-42 Identities = 98/240 (40%), Positives = 143/240 (59%), Gaps = 12/240 (5%) Query: 48 LEKVKKL--KSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFS 105 LE VKKL ++ P P + P+ +KILC+ +NY++H E + PP P F Sbjct: 66 LEIVKKLDERARGPFYKP-EEIKWEPPVPNPEKILCVAVNYREHGAETGIEPPDKPYFFP 124 Query: 106 KFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISA 165 KF + ++G + V ++ V +K+DWEVEL VV+GR + E AL +V GYTV D+S Sbjct: 125 KFPNALVGHEGYV-VKHRVVQKLDWEVELVVVMGRPGKYIEPERALDYVFGYTVGLDMSM 183 Query: 166 RDWQK--EKNMGQF----LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSS 219 RDWQ EK Q+ + GK+MDT P+GP + T DEV L + +NG L+Q Sbjct: 184 RDWQNPDEKTARQYGKNWIWGKTMDTAAPVGPYIATRDEVPDPNRLGLRLWVNGQLEQEG 243 Query: 220 STAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +T+QL+ +I L++ S +TL PGDLI TGTP GVG + ++L+ GD++ +E+E IG Sbjct: 244 NTSQLIFNIQQLIYWASQGITLRPGDLIFTGTPPGVGWAK--GKFLKGGDIVEAEVESIG 301 >UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Polynucleobacter sp. QLW-P1DMWA-1 Length = 299 Score = 173 bits (422), Expect = 3e-42 Identities = 92/257 (35%), Positives = 152/257 (59%), Gaps = 7/257 (2%) Query: 30 KADSSLPTTLLQILRNGDLEKVKKL-KSTKPATIPL---SSVTLTAPIHGVDKILCIGLN 85 K + P TL Q+L+ G+ + K+ S + +P S++T KI+C+GLN Sbjct: 36 KMKIAAPVTLDQLLQEGNAQGFNKVVASADQSGVPYLQESNITFGRLFKSPGKIVCVGLN 95 Query: 86 YKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRT-DVTKKVDWEVELCVVVGREASC 144 Y+ H E + P VP +F+K+++++ + ++I V+ K+D+E EL +V+G++ Sbjct: 96 YRAHADEVGMVHPRVPPLFNKYNNSLAAHNCLLQIPPPSVSYKLDYETELLIVIGKQMRN 155 Query: 145 VREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVE 204 V E AL +VAGY + D S+RD Q E GQ+++GK++D + P+GP +T D VG Sbjct: 156 VPESAALDYVAGYCTSNDFSSRDLQLELPSGQWMIGKTLDQYAPIGPYFVTGDLVGNPNN 215 Query: 205 LRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV--GMYRQPP 262 L+V +NG L+Q+S+T+ +H+ +L IS+ L PGD++ TGTP GV GM + Sbjct: 216 LQVKTWVNGELRQNSNTSDFIHNTQKMLSYISTYWALEPGDIVFTGTPQGVIAGMPKDKQ 275 Query: 263 EYLQPGDVLTSEIEKIG 279 +L+ GD + S +EK+G Sbjct: 276 VWLKKGDKVVSSVEKLG 292 >UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp. RHA1|Rep: Probable hydrolase - Rhodococcus sp. (strain RHA1) Length = 553 Score = 173 bits (421), Expect = 4e-42 Identities = 93/250 (37%), Positives = 147/250 (58%), Gaps = 19/250 (7%) Query: 32 DSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQ 91 D+ P LQ + G + +L ++ PA L API + C+G NY +H Sbjct: 30 DTGAPVRELQEIIAGGRAALGRLSTSTPA----EGGKLLAPITPHRNVFCVGRNYSEHAA 85 Query: 92 E------------QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVG 139 E P P+VF+K ++T+I PV TD+T +D+E E+ +++G Sbjct: 86 EFAESGFDATGSADGQHVPQYPVVFTKPAATVIACGDPVDPHTDITSALDYEGEIGIIIG 145 Query: 140 REASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEV 199 + AS V +DA+ +V GYT+ D++ARD Q++ Q+ +GKS+DTFCPLGP +T+DE+ Sbjct: 146 KRASKVSRDDAMDYVWGYTLINDVTARDLQRDHK--QWFIGKSLDTFCPLGPWAVTADEI 203 Query: 200 GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYR 259 +L++ +NG L+Q ++TAQL+ +P+++ +S+ +TL PGD+I TGTP GVG+ Sbjct: 204 DIN-DLQLQTRVNGELRQDTNTAQLIFDVPTIIETLSAGITLEPGDVIATGTPVGVGIGF 262 Query: 260 QPPEYLQPGD 269 PP+YL GD Sbjct: 263 DPPKYLVEGD 272 >UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Exiguobacterium sibiricum 255-15|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Exiguobacterium sibiricum 255-15 Length = 277 Score = 173 bits (420), Expect = 6e-42 Identities = 85/222 (38%), Positives = 131/222 (59%), Gaps = 3/222 (1%) Query: 67 VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126 + L AP ++C+G NY DH +E + ++F+K S+I+GP + + D+T+ Sbjct: 58 IRLLAPYIPPRNVICVGKNYADHIKEMDTAGAGKFVLFTKAPSSIVGPFEAIERHADLTQ 117 Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 186 ++D+E EL +++G + E+AL HV GY++ D++ARD QKE QF GKS+D F Sbjct: 118 QLDYEGELAIIIGTSGRDLTPENALDHVFGYSIVNDVTARDLQKEH--VQFFRGKSLDGF 175 Query: 187 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 246 CP GP ++T D ++ V +NG L+QS ST ++ + ++L +S MTL GD+ Sbjct: 176 CPFGPVIVTEDSFD-PTDVLVETRVNGQLRQSGSTKLMLRDVVTILTEVSRGMTLEAGDI 234 Query: 247 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288 I TGTP GVG +PP YLQ GDV+ IE IG ++ + Sbjct: 235 IATGTPAGVGHGMKPPTYLQDGDVVDISIEGIGHLQNHVKAY 276 >UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Xanthobacter sp. (strain Py2) Length = 281 Score = 173 bits (420), Expect = 6e-42 Identities = 92/262 (35%), Positives = 147/262 (56%), Gaps = 6/262 (2%) Query: 18 GYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVD 77 G + I+D+ + PT L+ G L++ + PA LS VTL I D Sbjct: 15 GLVTDGGIIDLTRRFPEAPT--LRTFIAGGLDRAAAVAGA-PADFALSEVTLAPVIPDPD 71 Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+C+GLNY DH E T P PM+F++++ + +G + ++ + + D+E EL V+ Sbjct: 72 KIVCVGLNYHDHVNETGRTVTPNPMLFARYAGSQVGAGTAL-VKPLESDEFDYEGELAVI 130 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +G+ + E DAL HVAGY D S RDWQ+ + QF+ GK+ GP ++++D Sbjct: 131 IGKAGRRISEADALSHVAGYACYNDASVRDWQRHTS--QFMPGKTFAATGAFGPWMVSAD 188 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 E+ L ++ LNG Q +S ++ IP+L+ S+++ L+PGD+I++GTPGGVG Sbjct: 189 EIPDPTRLTLATRLNGAQVQHTSVDLMITPIPTLIAYTSTILPLLPGDVIVSGTPGGVGA 248 Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279 R P +++ GDV+ E+ IG Sbjct: 249 RRTPKLFMKDGDVVEVEVSGIG 270 >UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: Bll6360 protein - Bradyrhizobium japonicum Length = 314 Score = 172 bits (419), Expect = 8e-42 Identities = 96/228 (42%), Positives = 136/228 (59%), Gaps = 10/228 (4%) Query: 60 ATIPLSSVTLTA-------PIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTII 112 A +P+SS+ + A P+ GV K + IGLNY DH E L P P+VF K +++ Sbjct: 73 ARVPVSSLPVVAGTPRFGVPVSGVGKFVAIGLNYADHAAEAGLPLPSEPIVFQKAITSLS 132 Query: 113 GPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK 172 GP+ V + + K DWEVEL +V+G AS V +ALQ+VAGY V D+S R++Q E+ Sbjct: 133 GPNDAVVLPRG-SLKGDWEVELGIVIGSRASYVEPVEALQYVAGYCVVNDVSEREYQMER 191 Query: 173 NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLL 232 G + GK DTF P+GP ++T+DEV L + LNG Q +T +V ++ Sbjct: 192 G-GTWDKGKGCDTFGPVGPWLVTTDEVPDPGRLDIWLELNGRRMQQGNTRTMVFGCAGIV 250 Query: 233 HRISSVMTLVPGDLILTGTPGGVGMYRQP-PEYLQPGDVLTSEIEKIG 279 +S MTL+PGD+I TGTP GVGM +P P YL+ GD++T I+ +G Sbjct: 251 SYVSQFMTLMPGDIIATGTPPGVGMGMKPDPIYLKVGDIMTLGIQGLG 298 >UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase; n=1; Frankia alni ACN14a|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase - Frankia alni (strain ACN14a) Length = 276 Score = 172 bits (419), Expect = 8e-42 Identities = 86/218 (39%), Positives = 125/218 (57%), Gaps = 3/218 (1%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 +PL L + KI+C+GLNY H +E TPP P +F+K++ +IGP + + Sbjct: 53 LPLDGADLAPLVPAPPKIICMGLNYATHLKEMGRTPPTHPTLFAKYTRALIGPTDDILV- 111 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 VT+ VDWE EL V+G E A + +AGYT+ D++ RDWQ QFL GK Sbjct: 112 PPVTEAVDWEGELAFVIGTTVRFADEAAAREAIAGYTIMNDVTMRDWQFRTL--QFLQGK 169 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 S + PLGP ++T DE+ +L + +NG + Q S T+ L+ ++ +S +TL Sbjct: 170 SFEGSTPLGPALVTPDELDNPADLALRTLVNGEVMQKSRTSDLLFPPVEIVRYVSQFITL 229 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 PGD++ TGTPGGVG R P YL GDV+T ++E +G Sbjct: 230 EPGDVLTTGTPGGVGHGRNPKVYLADGDVVTVDVEGLG 267 >UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Actinomycetales|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Arthrobacter sp. (strain FB24) Length = 290 Score = 172 bits (418), Expect = 1e-41 Identities = 100/240 (41%), Positives = 144/240 (60%), Gaps = 6/240 (2%) Query: 43 LRNGDLEKVKK-LKSTKPATIP-LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPV 100 L G +++V+ L + A IP S+ L AP+ ++ IGLNY H E P V Sbjct: 42 LGTGGIDRVRDALAAGDLAEIPDAGSLRLGAPLSRPGAVVGIGLNYAGHAAESGAAVPEV 101 Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREED-ALQHVAGYTV 159 P+VF K S+T+ GP I +++K DWEVEL VV+G+ AS ++ D A VAGY + Sbjct: 102 PVVFLKPSNTVAGPFDDAPI-PPLSRKYDWEVELAVVIGQRASYLKSVDEAAGCVAGYVL 160 Query: 160 AQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSS 219 A D+S RD+Q GQ++ GKS+ PLGP + + ++ + LR+ +NG L+Q S Sbjct: 161 ANDLSERDYQLPGAAGQWVKGKSLPASTPLGPWFVPAADLDPSA-LRLRTWVNGELRQDS 219 Query: 220 STAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 STA L+ +P+++H +S M L PGD+ILTGTP GV + + P YLQ GDVL E+E +G Sbjct: 220 STADLIFDVPAVVHHLSQFMVLEPGDVILTGTPEGVALSGRFP-YLQDGDVLELEVEGLG 278 >UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=3; Alphaproteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Roseobacter sp. MED193 Length = 285 Score = 171 bits (416), Expect = 2e-41 Identities = 85/234 (36%), Positives = 133/234 (56%), Gaps = 5/234 (2%) Query: 49 EKVKKLKSTKPATIPLSSVT---LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFS 105 E + +L S PAT+P++ V L P+ I C+GLNY DH E L P P++F+ Sbjct: 42 EMLTRLASVDPATLPMADVAGKPLAPPVAQPLNIWCVGLNYSDHAAEAGLPVPEEPILFN 101 Query: 106 KFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISA 165 K + T GP+ + +++ K+DWEVEL +V+ + A + + A+ H+AG+ + DIS Sbjct: 102 KSTVTYCGPNDDI-LKSAQMSKLDWEVELGIVISKPALNISRDQAMDHIAGFVLVNDISE 160 Query: 166 RDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLV 225 R WQ E++ GQ++ GKS FCP GP + T +E L + +NG Q+ +T ++ Sbjct: 161 RAWQMERS-GQWVKGKSFPNFCPTGPVLATKEEFADVQNLGMWLDVNGERMQTGNTGTMI 219 Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + +++ +S L PGDLI TGTP GVG PP +L GD ++ I+ +G Sbjct: 220 FDVATIVSYMSEFTRLEPGDLICTGTPPGVGAGMTPPVWLNEGDKVSLGIDGLG 273 >UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family protein; n=2; Candidatus Pelagibacter ubique|Rep: Fumarylacetoacetate hydrolase family protein - Pelagibacter ubique Length = 281 Score = 171 bits (415), Expect = 2e-41 Identities = 83/204 (40%), Positives = 131/204 (64%), Gaps = 2/204 (0%) Query: 82 IGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGRE 141 IGLNY +H +E P P++F+K +I+GP+ V I +KK+D EVE+ V+G++ Sbjct: 76 IGLNYVEHAKETGAKTPDNPVLFNKSVHSIVGPNDNVII-PKTSKKLDHEVEIAFVIGKK 134 Query: 142 ASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGA 201 A V E+DA ++ GY + DIS R+WQKEK GQ++ GKS DTF PLGP ++T DE+ Sbjct: 135 AKRVLEKDAQDYIFGYCICNDISEREWQKEKG-GQWVKGKSGDTFGPLGPYLVTKDEIQD 193 Query: 202 AVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP 261 L ++ +NG Q+ +T Q++ + L+ I+S +TL+PGD++ TGTP GVG+ P Sbjct: 194 VNNLNLTLDVNGHRHQTGNTNQMIFNFNFLVAHITSFITLMPGDIVTTGTPPGVGLGMDP 253 Query: 262 PEYLQPGDVLTSEIEKIGAFDVRI 285 P +L+ GD + I+ +G+ + ++ Sbjct: 254 PVFLKEGDEMKLNIDSLGSQNSKV 277 >UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farcinica|Rep: Putative hydrolase - Nocardia farcinica Length = 285 Score = 169 bits (412), Expect = 5e-41 Identities = 94/222 (42%), Positives = 125/222 (56%), Gaps = 7/222 (3%) Query: 65 SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDV 124 S+ +TAP KI+C G NY+ H E P P +F+KF+ T+ D + + Sbjct: 53 SAPVVTAP----RKIVCCGHNYRAHIAELGRAEPEFPTLFAKFADTLTAWDADITLGMAA 108 Query: 125 TKK-VDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183 +DWE EL VVVG E A +AGYTVA D S R WQ+ Q+L GK+ Sbjct: 109 ADAGLDWEAELAVVVGAELRRADRATARAGIAGYTVANDFSVRTWQRRT--AQWLQGKAF 166 Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243 D PLGP ++T DE LR++C +NGV++Q ST L+ +LL IS+ TL P Sbjct: 167 DATTPLGPDLVTPDEADPGDGLRITCRVNGVVEQCGSTDDLLFDPAALLSYISAFTTLRP 226 Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 GD++LTGTPGGVG+ PP +L GDV+ +EIE IG RI Sbjct: 227 GDVVLTGTPGGVGVAADPPRHLGDGDVVETEIEGIGLLRNRI 268 >UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctional decarboxylase/isomerase; n=4; Pezizomycotina|Rep: Function: E. coli hpaG is a bifunctional decarboxylase/isomerase - Aspergillus niger Length = 358 Score = 169 bits (412), Expect = 5e-41 Identities = 84/208 (40%), Positives = 129/208 (62%), Gaps = 3/208 (1%) Query: 69 LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128 L P+ ++CIGLNYK H +E +L P P VF+K + + GP + + I D + Sbjct: 54 LLPPVPNTPLVICIGLNYKQHAKEASLDVPTYPPVFTKPADVLAGPFETIPIHRDAQSHL 113 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFC 187 D+E EL VV+G++A V EDAL +V GYT D+SAR++Q E + GQF KS D F Sbjct: 114 DYEGELTVVIGKDAKNVSAEDALDYVLGYTAGNDLSARNFQMPEASGGQFCYAKSFDKFA 173 Query: 188 PLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLI 247 P+G ++++ EV +L + +NGV+KQ+++T+ ++ + ++ +S MTL G LI Sbjct: 174 PIGHVLVSAQEVQDPQQLSLVTKVNGVVKQTTNTSDMIWGVRDIVSHLSRGMTLRKGTLI 233 Query: 248 LTGTPGGVGMYRQPPEYLQPGDVLTSEI 275 +TGTP GVG +R+ E+LQ GDV+ E+ Sbjct: 234 MTGTPSGVGFFRK--EFLQDGDVVEVEL 259 >UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4; Thermoprotei|Rep: Fumarylacetoacetate (FAA) hydrolase - Sulfolobus acidocaldarius Length = 307 Score = 169 bits (412), Expect = 5e-41 Identities = 104/301 (34%), Positives = 168/301 (55%), Gaps = 26/301 (8%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKA-----DSSLPT---TLLQILRNGD----- 47 MKL+QFS + + R+G +VD+ KA D++ P + ++ G+ Sbjct: 1 MKLLQFS-PNLGEQKRIGVYHEGKVVDLVKAYEMVYDATPPNWFFNMRDLIEGGEGSLYL 59 Query: 48 ----LEKVKKLKST--KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVP 101 L+ KL S + A + ++ P+ +KI + +NY+ H QE N PP P Sbjct: 60 VRRVLDDFNKLDSVIKRSAELDPENIIYYPPVTDPEKIFLLAVNYRAHGQETNNNPPKEP 119 Query: 102 MVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQ 161 +F+KF++T+IG +QPV + + KVD+E+EL V++G+ A V AL +V GYT+ Sbjct: 120 YIFTKFNNTLIGHNQPV-LFPRASNKVDYEIELAVIMGKRAKYVNSSKALDYVFGYTIFN 178 Query: 162 DISARDWQ--KEKNMG-QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQS 218 DIS RD Q E G +++ GK +DT P+GP ++T DE+ LR+ +NG ++Q Sbjct: 179 DISFRDKQFPPEIPYGMRWVHGKGLDTAAPMGPWIVTKDEIDNINNLRLKLRVNGEIRQD 238 Query: 219 SSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278 + ++ + ++ +S+ +TL PGD+I TGTP GV + +YL+PGDV+ +EI KI Sbjct: 239 AYAEDMIFKVEQIIEYLSNGITLKPGDVISTGTPSGVAL--ATGKYLKPGDVMEAEISKI 296 Query: 279 G 279 G Sbjct: 297 G 297 >UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Candidatus Nitrosopumilus maritimus SCM1 Length = 289 Score = 169 bits (412), Expect = 5e-41 Identities = 94/253 (37%), Positives = 144/253 (56%), Gaps = 5/253 (1%) Query: 35 LPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQN 94 +P + L +G +++K P LS L API +KI+C+ NY DH +EQ Sbjct: 36 IPHNVKDFLFDGWFDEIKNKIQDLPYEENLSKFKLLAPIPNPNKIICLAFNYVDHAKEQG 95 Query: 95 LTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHV 154 LT P P + K + + G + + VT+ +D+EVEL +++G+ + E+A V Sbjct: 96 LTAPEDPAIVIKPRTALNGNNANIECPDFVTQ-LDYEVELALIIGKNCKNISVEEAQNVV 154 Query: 155 AGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNG 213 GY V D+SARD Q K+K QF GKS D+F P GP + T+DE+ L+++ +NG Sbjct: 155 FGYMVFNDVSARDIQFKDK---QFTRGKSFDSFAPCGPWITTADEIQEPQNLKLTTKING 211 Query: 214 VLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTS 273 L+Q+SST+ + IP ++ +IS VMTL GD+I TGTP GV + + +L+ GD + Sbjct: 212 ELRQNSSTSNMFIKIPEIISKISKVMTLEKGDIISTGTPAGVMLNKPNAIFLKDGDKVEM 271 Query: 274 EIEKIGAFDVRIE 286 EIE +G + I+ Sbjct: 272 EIEGLGVLNNTIK 284 >UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase precursor; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase precursor - Polynucleobacter sp. QLW-P1DMWA-1 Length = 349 Score = 169 bits (411), Expect = 7e-41 Identities = 91/256 (35%), Positives = 149/256 (58%), Gaps = 13/256 (5%) Query: 36 PTTLLQILRNGD---LEKVKKLKSTKPATIPLSSVTLTAPIHGVD-KILCIGLNYKDHCQ 91 PT+++ + +G+ L+ K+ ++ V L +PI I C+G NY DH + Sbjct: 88 PTSMISLAGSGNQGLLQLAAIFKNRGSNLANVNQVILLSPIPKPQANIYCVGWNYLDHFE 147 Query: 92 E--------QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREAS 143 E P VP++F+K + T+ GP + ++ +DWE EL VV+G++ Sbjct: 148 EGLKHRADTAVKEYPKVPVLFTKGTQTMNGPFDNIPYDAGISTMIDWEAELAVVIGKKGK 207 Query: 144 CVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAV 203 + EE+A+ +V GY+ D +ARD Q+++ GQ+ GKS+D P+GP V+T+ V Sbjct: 208 NISEENAMDYVFGYSAYNDTTARDIQQKRQSGQWFKGKSLDGHGPMGPWVVTAGGVNLD- 266 Query: 204 ELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPE 263 + R+ CS+NGV KQ++S Q+ IP+++ +S +TL+PGD+I TGTP GVG R P E Sbjct: 267 DTRIICSVNGVEKQNASYKQMYFKIPAIIAELSRGLTLLPGDIIATGTPSGVGAGRTPQE 326 Query: 264 YLQPGDVLTSEIEKIG 279 +++PGD++ + I IG Sbjct: 327 FMKPGDMMETNITGIG 342 >UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiales|Rep: Putative hydrolase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 304 Score = 169 bits (410), Expect = 9e-41 Identities = 87/223 (39%), Positives = 131/223 (58%), Gaps = 9/223 (4%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP-------PPVPMVFSKFSSTIIGPDQ 116 L +V + P+ + C+G NY++H E NL P F+K + +IG Sbjct: 76 LQAVRVLPPLPMARNVFCVGRNYREHIIEGNLARGRPANSFPEAIEFFTKAPTAVIGHGG 135 Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176 V+ +T +D+EVEL +V+GR + + E AL HV GYT+ DI+ARD Q GQ Sbjct: 136 HVKRHAGLTDSLDYEVELAIVIGRAGADIPREKALDHVFGYTIVNDITARDLQARH--GQ 193 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 + GKS+DT CP+GP V+ + A L VS S+NG L+Q +T+ ++ + +++ ++S Sbjct: 194 WFKGKSLDTSCPMGPVVVHRSAIPDANNLAVSLSVNGELRQQDNTSDMIFDVAAVVAQLS 253 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + MTL+PGD+I TGTP GVG PP LQ GDV+++ +E IG Sbjct: 254 AGMTLLPGDVIATGTPKGVGFALTPPRCLQVGDVVSASVEHIG 296 >UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Marinomonas sp. MED121 Length = 298 Score = 169 bits (410), Expect = 9e-41 Identities = 92/262 (35%), Positives = 153/262 (58%), Gaps = 7/262 (2%) Query: 20 LEGDDIVDINKADSSLPTTLLQILRNGDL-EKVKKLKSTKPATIPLSSVTLTAPIHGVDK 78 ++G+ ++I+ D+ + L QI+ N L EK+ S P IP+S + + P+ K Sbjct: 25 IQGELAINISSQDNQFGSDLSQIINNPQLLEKISGYSSA-PG-IPVSQIQPSLPLQHPGK 82 Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138 ++C+GLNY DH +E P P +F + S+++ P Q +R V+ ++D+E EL ++V Sbjct: 83 VICLGLNYMDHIKEGGYKVPDYPALFMRSHSSLM-PAQAPMVRPKVSVQLDYEAELMLIV 141 Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE 198 G+ + E AL +V GYT+ D S RD+Q++ + Q+ GK+ D +GP ++T DE Sbjct: 142 GKHGRHIPESKALDYVFGYTIFNDGSVRDYQRKTH--QWTPGKNFDNTGAIGPIIVTPDE 199 Query: 199 VGAAVE-LRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 + L++ + + QS++T++++ S+ ++ ISS TL PGDLI GTP GVG Sbjct: 200 LPEGAHGLKIETRVGDEILQSANTSEMLWSVARVIAEISSYTTLEPGDLIAMGTPPGVGH 259 Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279 R P +L+PG+V+ EIE IG Sbjct: 260 ARSPARWLEPGEVVEVEIEGIG 281 >UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=8; cellular organisms|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Thermoanaerobacter tengcongensis Length = 242 Score = 168 bits (409), Expect = 1e-40 Identities = 98/238 (41%), Positives = 143/238 (60%), Gaps = 14/238 (5%) Query: 49 EKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFS 108 +KV LK + L+ V L P K +C+GLNYKDH +E P P +F K S Sbjct: 19 DKVILLKEGETFLYGLNEVKLLPPCIP-SKAICVGLNYKDHIEEMGDKIPEEPTLFIKPS 77 Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168 + +IGPD + I +++++VD+E EL VV+GR+A V E+A ++ GYT+A D++ARD Sbjct: 78 TAVIGPDDYI-ILPEMSRRVDYEGELAVVIGRKAKNVSIEEAKNYILGYTIANDVTARDL 136 Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSI 228 Q + GQ+ KS DTF P+GP ++T + L ++ +NG +KQ S+T L+ ++ Sbjct: 137 QAKD--GQWTRAKSFDTFLPIGPWIVTDLD---PTSLNITTYVNGEVKQKSNTKYLIFNV 191 Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286 L+ IS +MTL PGD+ILTGTP GVG L+ GDV+T EIE IG R++ Sbjct: 192 FKLVSFISHIMTLNPGDVILTGTPSGVGP-------LKSGDVVTIEIEGIGKLTNRVK 242 >UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase; n=1; Lactobacillus plantarum|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase - Lactobacillus plantarum Length = 276 Score = 168 bits (409), Expect = 1e-40 Identities = 83/218 (38%), Positives = 128/218 (58%), Gaps = 3/218 (1%) Query: 69 LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128 L API +I +G+NY+DH E ++T P VP +F+KFSS++ + + T Sbjct: 62 LAAPITAPRQIFAVGMNYRDHSAEIHITLPKVPSIFTKFSSSLAPANVTMATHGPET--- 118 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188 DWE EL V++G+ + DA+ HVAG V +D+S R Q E + QF +GKS + + P Sbjct: 119 DWETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQFENDNPQFSIGKSFENYAP 178 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 +GP + T DE+ + ++ ++NG Q + +QL+ +P L+H +S+V L PGDLI Sbjct: 179 VGPWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIF 238 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286 TGTP G G+ R P +LQ GD L +I +G ++ I+ Sbjct: 239 TGTPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK 276 >UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family protein; n=5; Pezizomycotina|Rep: Fumarylacetoacetate hydrolase family protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 289 Score = 168 bits (409), Expect = 1e-40 Identities = 88/216 (40%), Positives = 130/216 (60%), Gaps = 4/216 (1%) Query: 69 LTAPIHGVD--KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP--DQPVRIRTDV 124 L AP+ D + C+GLNY+ H +E NL P P++F K ++I GP D P+ Sbjct: 60 LLAPLARKDIRTVRCLGLNYEQHARESNLPIPKYPVLFYKPVTSIAGPRDDIPISTMAQE 119 Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184 + +D+E EL +V+G+EA V E AL +V GY V D+S RDWQ ++ GQ+ LGK D Sbjct: 120 GEGLDYECELVIVIGKEAKDVPESRALDYVLGYAVGNDVSHRDWQIKRGGGQWGLGKGFD 179 Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244 + P GP +++S + L +S LNG + QSSST ++ S+ ++ +S TL+PG Sbjct: 180 GWAPFGPGIVSSRLIRDPNALHISTRLNGQVVQSSSTKDMIFSVAKVVAFLSQGTTLLPG 239 Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280 DLI TGTP GVGM R+P +L+ GD + +E +G+ Sbjct: 240 DLIFTGTPQGVGMGRKPALWLKDGDQVEVSLEGVGS 275 >UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=4; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Delftia acidovorans SPH-1 Length = 309 Score = 166 bits (403), Expect = 7e-40 Identities = 87/247 (35%), Positives = 131/247 (53%), Gaps = 3/247 (1%) Query: 39 LLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP 98 LL +LR L ++++ ++ + I K++C+GLNYK H E Sbjct: 59 LLSVLRAQALGELEQALQAGAVSVDAAQTQALPVIPNPGKLICVGLNYKTHVAETRRADS 118 Query: 99 PVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYT 158 P +F +F+ ++ D +R +++ DWE EL V+GR + +EDA H+AGY Sbjct: 119 EHPSLFLRFNDSLAA-DGDELLRPAFSERFDWEGELAFVIGRGGRHIAKEDAFDHIAGYA 177 Query: 159 VAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQS 218 D+S RDWQ+ + QF GK+ P GP ++T DEV L + LNG + Q Sbjct: 178 CFNDVSVRDWQRHTH--QFTPGKNFPGTAPFGPWLVTRDEVADVRSLALQTRLNGSVMQQ 235 Query: 219 SSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278 +S L+ IP+++ +S L PGD+I TGTPGGVG R+PP Y++ GDV+ EI + Sbjct: 236 ASLGDLIFDIPTIVAYVSRFTPLSPGDVIATGTPGGVGDRREPPLYMKHGDVVEVEITGL 295 Query: 279 GAFDVRI 285 G RI Sbjct: 296 GVLRNRI 302 >UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomycotina|Rep: RIB40 genomic DNA, SC138 - Aspergillus oryzae Length = 582 Score = 166 bits (403), Expect = 7e-40 Identities = 98/281 (34%), Positives = 161/281 (57%), Gaps = 20/281 (7%) Query: 16 RVGYLE-GDDIVDINKADSSLP-TTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPI 73 R+G+L+ +V S P T L Q++ G+ + +K++ + LSSV PI Sbjct: 20 RIGHLDFRTSMVTPLSFKSGTPLTNLYQVITVGE----QGIKASGAQSFLLSSVKHLPPI 75 Query: 74 HGVDKILCIGLNYKDHCQEQNLT---------PPPVPMVFSKFSSTIIGPDQPVRIRTDV 124 G D +L +G NY +H +E N + P P++F+K +++IIGP++P+ + Sbjct: 76 SGRD-VLAVGKNYVEHAKEFNASGYDASDKSDQPTHPVIFTKRATSIIGPEEPILLHPKF 134 Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184 T VD+E E+ V++G+ + EE+A HV GYT+ D++AR+ Q++ QF LGKS D Sbjct: 135 TSTVDYEGEIGVIIGKPGFQISEENASDHVWGYTIVNDMTARERQRDHK--QFFLGKSPD 192 Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244 TFCP+GP + + + L++ +N L+Q +S + L+ SIP+L+ IS+ TL G Sbjct: 193 TFCPMGPVAVPKESL--PENLKIQTFVNQELRQEASLSDLIFSIPTLIATISAGQTLQTG 250 Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 D+I TGTP GVG +P ++LQ GD ++ + +G R+ Sbjct: 251 DVIATGTPAGVGFGFRPMKFLQTGDEISVSVTGLGTLTNRM 291 >UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=6; Enterobacteriaceae|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Enterobacter sp. 638 Length = 287 Score = 165 bits (402), Expect = 9e-40 Identities = 97/280 (34%), Positives = 150/280 (53%), Gaps = 12/280 (4%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILR-NGDLEKVKKLKSTKP 59 MKL F YK G ++ D +V++ + + L +L+ NG E + L Sbjct: 1 MKLASFIYKGQRS---YGIVKADGVVNLGRRLGDRFSDLKALLQGNGMAEATRYLNDA-- 55 Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119 +PL ++T I +KILC+G+NY + QE + P P +F +F + G + PV Sbjct: 56 VDVPLDAITFLPVIEHPEKILCVGMNYAEKRQEFD-QHNPAPTLFVRFPDSQTGHNSPV- 113 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179 ++ + + D+E EL V++G+ + +DAL+HVAGY+ D SARDWQ F Sbjct: 114 LKPRHSSEFDYEGELAVIIGKGGENISRDDALRHVAGYSCYMDGSARDWQHT----WFTA 169 Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239 GK+ GP + T+DE+ L + LNG + Q +T+ ++H + L+ IS+ Sbjct: 170 GKNWRQTGAFGPWMATADEIPDPHRLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFT 229 Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 L PGD+I+TG+PGGVG R PP ++Q GD + EIE IG Sbjct: 230 RLSPGDVIITGSPGGVGKKRNPPLFMQEGDRIEVEIENIG 269 >UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rhodobacterales bacterium HTCC2654|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rhodobacterales bacterium HTCC2654 Length = 279 Score = 165 bits (402), Expect = 9e-40 Identities = 101/283 (35%), Positives = 153/283 (54%), Gaps = 14/283 (4%) Query: 4 VQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIP 63 ++F+ + +R G +EGD I + D L+ +GDL + +PA + Sbjct: 1 MKFATIEHGGQLRFGLVEGDAIHLAPEGDR------LRAHLDGDLAALATRLRGEPA-LS 53 Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQN----LTPPPVPMVFSKFSSTIIGPDQPVR 119 L+ VT T + ++LCIGLNYKDH E T P P+VF +F++++ + + Sbjct: 54 LAGVTYTPVVPDAQQVLCIGLNYKDHRAETKGEVGTTYPDNPIVFMRFATSLAAHGESLP 113 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179 I V++ VD+E EL V++G+ + + DA+ HVAGY DIS RDWQ + Q+ Sbjct: 114 I-PKVSEVVDYEAELAVIIGKGGRYIAKADAMSHVAGYAPFNDISMRDWQMKGE--QWGP 170 Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239 GK+ P GP ++T DEVG E + L+G + Q S L+ IP+L+ S+ + Sbjct: 171 GKNFPKSGPFGPVMVTPDEVGDLGETGIRLILDGEVLQESWIKHLIFDIPTLISYCSNFV 230 Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 L PGD+I+TGTPGGVG R+PP L PG E++ IG + Sbjct: 231 ELRPGDVIVTGTPGGVGFVRKPPILLAPGKTCVVEVDGIGRLE 273 >UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Euryarchaeota|Rep: Uncharacterized protein MJ1656 - Methanococcus jannaschii Length = 237 Score = 165 bits (402), Expect = 9e-40 Identities = 82/202 (40%), Positives = 131/202 (64%), Gaps = 13/202 (6%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+C+GLNY DH +E N+ P P++F K +S II + + IR ++K+VD+EVEL +V Sbjct: 39 KIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYI-IRPRISKRVDYEVELAIV 97 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +G++ +++++A ++ GYT+ D++ARD Q++ GQ+ KS DTFCP+GP ++ Sbjct: 98 IGKKCKNIKKDEANDYIMGYTILNDVTARDLQQKD--GQWTRAKSFDTFCPIGPRIVKDI 155 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 + + L + C +NG +KQ S+T ++ + L+ ++S+MTL PGD+I TGTP GVG Sbjct: 156 D---PMNLNIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVG- 211 Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279 L+ GDV+ EIE IG Sbjct: 212 ------ELKAGDVVECEIEGIG 227 >UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE; n=41; Bacteria|Rep: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE - Mycobacterium tuberculosis Length = 239 Score = 165 bits (400), Expect = 2e-39 Identities = 87/217 (40%), Positives = 131/217 (60%), Gaps = 11/217 (5%) Query: 63 PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRT 122 PL+ V L API K++C+G NY DH E PP P++F K ++ IIGP+ P+R+ Sbjct: 22 PLADVRLLAPILA-SKVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPA 80 Query: 123 DVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKS 182 + + V +E EL +V+GR V A+ ++ GYT+ D+SARD Q+ GQ+ K Sbjct: 81 NASP-VHFEGELAIVIGRACKDVPAAQAVDNILGYTIGNDVSARDQQQSD--GQWTRAKG 137 Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242 DTFCP+GP ++T +L + +NG +KQ + T+ ++H I +++ IS++MTL+ Sbjct: 138 HDTFCPVGPWIVTDLAPFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLL 197 Query: 243 PGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 PGDLILTGTP GVG ++ GD ++ IE IG Sbjct: 198 PGDLILTGTPAGVGP-------IEDGDTVSITIEGIG 227 >UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase; n=8; Pezizomycotina|Rep: Predicted fumarylacetoacetate hydralase - Aspergillus oryzae Length = 289 Score = 164 bits (398), Expect = 3e-39 Identities = 85/216 (39%), Positives = 126/216 (58%), Gaps = 4/216 (1%) Query: 69 LTAPIHGVD--KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP--DQPVRIRTDV 124 L AP+ D + C+GLNY+ H +E NL P P++F K + I GP D P+ Sbjct: 60 LLAPLAREDIATVRCLGLNYEQHARESNLPIPKYPVLFYKPITAITGPYDDIPICSMAQD 119 Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184 + +D+E EL +V+G++A + EE AL +V GY V DIS RDWQ ++ GQ+ LGK D Sbjct: 120 VEGLDYECELVLVIGKQAKNIPEEQALDYVLGYAVGNDISHRDWQLKRGGGQWGLGKGFD 179 Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244 + P GP ++++ + L +S +NG QSSST ++ + + +S TL+PG Sbjct: 180 GWAPFGPGIVSTKLIRNPNALNISTKVNGQTVQSSSTKDMIFGVAQTVSFLSQGTTLLPG 239 Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280 DLI TGTP GVGM R+P +L GD + +E +G+ Sbjct: 240 DLIFTGTPQGVGMGRKPAAWLTNGDQVEVSLEDVGS 275 >UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Bacillus sp. B14905|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus sp. B14905 Length = 314 Score = 163 bits (397), Expect = 4e-39 Identities = 84/211 (39%), Positives = 128/211 (60%), Gaps = 4/211 (1%) Query: 71 APIHGVDK-ILCIGLNYKDHCQEQNLTPPPVP-MVFSKFSSTIIGPDQPVRIRTDVTKKV 128 +PI K I+CIG NY +H +E P MVF+K + I Q + I D++ K+ Sbjct: 85 SPIPRTPKNIMCIGKNYNEHAKEMGAEAAPKELMVFTKSPTAIAADGQTLSIHADLSSKM 144 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188 D+E EL +V+G+ + + A +V GYT+A DI+ARD Q++ QF LGKS++ CP Sbjct: 145 DYEGELAIVIGKRGKNIPKNLAYDYVFGYTIANDITARDLQEKHK--QFFLGKSLEGTCP 202 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 LGP ++T DE+ +L V +N ++Q+ ST ++ S+ +L+ +S +TL PGD+IL Sbjct: 203 LGPYLVTKDEIPNPQDLTVVTKVNDEVRQNGSTKDMMFSVETLVSILSQHVTLEPGDVIL 262 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 TGTP GVG PP++L+ GD + I+ IG Sbjct: 263 TGTPAGVGKGMNPPQFLKAGDTVKVSIQGIG 293 >UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Hyphomonas neptunium ATCC 15444|Rep: Fumarylacetoacetate hydrolase family protein - Hyphomonas neptunium (strain ATCC 15444) Length = 281 Score = 163 bits (396), Expect = 5e-39 Identities = 82/232 (35%), Positives = 137/232 (59%), Gaps = 5/232 (2%) Query: 48 LEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKF 107 L ++ ++ + T+PL V L P + K++C+GLNYK+H E + PP P +F+K Sbjct: 45 LSQLGEIADSAGETLPLDQVGLLMPSEPLSKLVCLGLNYKNHVDETHNDLPPNPALFTKV 104 Query: 108 SSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD 167 + +++ + V +R V+++ D+E E+CVV+G+ + E AL HV GYT+ D S RD Sbjct: 105 ADSLVPHGEAV-LRPKVSEQFDYEGEICVVIGKGGRHISRETALDHVFGYTIMLDGSVRD 163 Query: 168 WQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHS 227 +QK GK+ LGP ++T+DE+ +++ LNG QS++ +++ Sbjct: 164 YQKHSVSA----GKNFWRSGALGPWIVTADEIPDPSVMKLETRLNGETVQSTTADLMLYD 219 Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 IP+ + +S L PGD+I TGTPGGVG R+PP +++ GDV+ ++ +IG Sbjct: 220 IPTAIAYVSQWTPLAPGDVIATGTPGGVGARRKPPLWMKAGDVIEVDVSQIG 271 >UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase; n=2; Rhodococcus|Rep: Possible fumarylacetoacetate hydrolase - Rhodococcus sp. (strain RHA1) Length = 296 Score = 163 bits (395), Expect = 6e-39 Identities = 91/221 (41%), Positives = 124/221 (56%), Gaps = 4/221 (1%) Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119 A P+ L AP+ +I IG+NY DH +E LT P P VF+KF ++I GP + Sbjct: 54 AGAPVVESELGAPVPRPGQIFAIGVNYADHVEESGLTLPDAPFVFTKFPASITGPYDTIE 113 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQFL 178 + VD+EVEL V+G+EA V + ++VAG T+ QD+S RD Q QF Sbjct: 114 HPGGL---VDFEVELVAVIGKEARHVPVAEGWEYVAGLTLGQDLSERDLQLSGPPPQQFT 170 Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238 LGKS F P+GP ++T DE ++ VS L+G L Q+S T L+ IP L+ +SS+ Sbjct: 171 LGKSFAGFAPIGPVLVTPDEFADPDDIEVSTILSGELMQNSRTRHLIFPIPVLVSYLSSI 230 Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + L PGDLI TGTP G+G R P + D L S + IG Sbjct: 231 LPLRPGDLIFTGTPSGIGFTRDPKRLIGVDDELVSRADTIG 271 >UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Hyphomonas neptunium ATCC 15444|Rep: Fumarylacetoacetate hydrolase family protein - Hyphomonas neptunium (strain ATCC 15444) Length = 277 Score = 163 bits (395), Expect = 6e-39 Identities = 99/283 (34%), Positives = 153/283 (54%), Gaps = 26/283 (9%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60 M+LV+F ++ ++R G+LEGD +V + DS + L + K A Sbjct: 1 MRLVRF---EAEGHVRFGHLEGDTVVPV-AGDS-----FIDALEGRE----------KGA 41 Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQ----NLTPPPVPMVFSKFSSTIIGPDQ 116 + LS V L AP+ KIL IG+NY H E N P V F+K ++ + GP Sbjct: 42 PLALSVVRLLAPVPRPRKILGIGVNYAAHAAESVSFINTAKPEVQKWFNKQATAVNGPYD 101 Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176 PV + V+ ++D+E EL V+G+ V E A++ VAG+ + D S RDWQK Sbjct: 102 PVHLPR-VSSQLDYEGELVAVIGKHGRHVPAERAMEIVAGFCIGCDYSVRDWQKASQT-- 158 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 ++GK DT P GP ++T DE+G +L + +NG L+QS ++H + + + ++ Sbjct: 159 MIMGKGFDTHAPFGPALVTPDELGDISDLEIRSFVNGELRQSGRPRDMIHDVGAQIAHLT 218 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + TL PGD+I TGTP GVG PP++L+ GD + EI+++G Sbjct: 219 AAFTLEPGDVIFTGTPAGVGAGFDPPKWLKAGDRVRIEIDRLG 261 >UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=5; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Nocardioides sp. (strain BAA-499 / JS614) Length = 284 Score = 162 bits (394), Expect = 8e-39 Identities = 86/221 (38%), Positives = 128/221 (57%), Gaps = 3/221 (1%) Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL-TPPPVPMVFSKFSSTIIGPDQPV 118 A + + L AP + + IGLNY++H E P +P VF+KF+S+I GP V Sbjct: 59 ADVVIDPDLLGAPSPRPTQAIAIGLNYEEHAHETGYQVPTQLPPVFAKFASSITGPRGLV 118 Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFL 178 + DWEVE+ V+GR A + ++A HVAG TV QD+S R Q QF Sbjct: 119 DLPPG--GHTDWEVEVVAVIGRTAHRISPDEAWGHVAGLTVGQDLSERISQMAGPAPQFG 176 Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238 L KS F P+GP ++T +E+ +L + C+++G Q T++L+ SIP + +S V Sbjct: 177 LAKSFPGFSPMGPWLVTPEELADPDDLALGCAIDGETVQDGRTSKLIFSIPRSIAALSQV 236 Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +TL+PGD++ TGTP GVG+ R P +L+PG+ L + +E IG Sbjct: 237 LTLLPGDVVFTGTPDGVGLGRSPQRFLRPGETLRTWVEGIG 277 >UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 282 Score = 162 bits (393), Expect = 1e-38 Identities = 85/220 (38%), Positives = 123/220 (55%), Gaps = 4/220 (1%) Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119 A IPL V L PI DK+LC+ N+++ +E P P+VF++F+++ G QP+ Sbjct: 54 ADIPLDQVRLLPPIPNPDKVLCVATNFREPAREGK-PEPEYPLVFTRFANSFTGHGQPLA 112 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179 + D ++ D+E EL VV+G+ + +A+ HV GY D S RDWQK QF Sbjct: 113 -KPDRSEAYDFEGELAVVIGKGGHRIPASEAMAHVGGYCCLNDGSVRDWQKHST--QFTP 169 Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239 GK+ GP ++T+DE+ L + +NGV+KQ +++ IP L+ S+ Sbjct: 170 GKNFHRSGSFGPWIVTADEIPDPTVLTLQTRVNGVVKQRIGIDRMIFDIPWLIAYFSTFT 229 Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 LVPGD+I TGTP G G R PPEYL GD + EI +IG Sbjct: 230 PLVPGDVIATGTPSGFGSSRTPPEYLSIGDAIEVEISEIG 269 >UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=5; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 287 Score = 161 bits (391), Expect = 2e-38 Identities = 94/269 (34%), Positives = 149/269 (55%), Gaps = 10/269 (3%) Query: 16 RVGYLEGDDIVDINKADSSLPTTLLQILRNG--DLEKVKKLKSTKPATIPLSSVTLTAPI 73 R+G +E ++VD+ + LP ++ IL G LE V+ L + + + L+ V L API Sbjct: 13 RIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVR-LAAGRANRLALNEVQLNAPI 71 Query: 74 HGVDKILCIGLNYKDHCQE---QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDW 130 K L +GL++K E + + P + F+K + I GP PV + V+ ++D+ Sbjct: 72 TRPRKFLGLGLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVHMPR-VSSELDY 130 Query: 131 EVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLG 190 E EL +V+G+ R DA + +AG+ V D S RDWQ+ LGKS DT P+G Sbjct: 131 EGELALVIGKRIRHARTSDAEKIIAGFLVCNDFSVRDWQRRSPTAT--LGKSFDTHGPIG 188 Query: 191 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 250 P + T DEV + LR+ ++G L+Q +T L+++ ++ +S+ TL PGD++ TG Sbjct: 189 PWLTTFDEVDPS-SLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEPGDILATG 247 Query: 251 TPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +P G G Y +PP YL+ G + EIE +G Sbjct: 248 SPTGAGQYMRPPTYLKTGQTVRVEIEGLG 276 >UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaster|Rep: CG11251-PA - Drosophila melanogaster (Fruit fly) Length = 338 Score = 161 bits (390), Expect = 2e-38 Identities = 84/211 (39%), Positives = 122/211 (57%), Gaps = 7/211 (3%) Query: 69 LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128 L PI KI+ + NY D+C EQ+++ P P KF+S+I G +R + K + Sbjct: 124 LLPPIDSPSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSSA-KHI 182 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188 D+ +L VV+G+ V ++AL HV G+ V QDI ARDW L G SMDTF P Sbjct: 183 DYGCQLAVVMGKRCREVSPKEALNHVFGFMVVQDIVARDWNVP------LGGHSMDTFLP 236 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 LGP ++ V L + +NG +Q+ +T ++ I L+HR+S +TL PGD+IL Sbjct: 237 LGPTIVHRCHVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDIIL 296 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 TGTP G G +R P +L+PGD++ SEI+ +G Sbjct: 297 TGTPAGSGAFRHPSCFLKPGDLIESEIQNLG 327 >UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=4; Archaea|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Methanobacterium thermoautotrophicum Length = 260 Score = 161 bits (390), Expect = 2e-38 Identities = 89/224 (39%), Positives = 130/224 (58%), Gaps = 14/224 (6%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123 L V + P+ K++C+GLNY+DH E + P P++F K +T+IG V I + Sbjct: 46 LDDVRILPPV-SPSKVVCVGLNYRDHAAELGMDIPDEPIIFLKPPTTVIGSGDTV-IYPE 103 Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183 ++ +VD+EVEL VV A V A + +AGYTV D++ARD Q+ GQ+ KS Sbjct: 104 MSSEVDYEVELAAVVSERARRVDSSAASEFIAGYTVLNDVTARDLQRRD--GQWTRAKSF 161 Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243 DTFCP+GP + T L +S LNG ++QSS+T+ ++ ++ LL IS VMTL P Sbjct: 162 DTFCPIGPVIETDVTPD---NLDISLKLNGEVRQSSNTSNMIFTVHELLEFISHVMTLEP 218 Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 GD+I TGTP GVG + PGD + + +E +G R+E+ Sbjct: 219 GDVIATGTPPGVGQ-------MVPGDTVRATVEGVGTLVNRVER 255 >UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE DECARBOXYLASE; n=19; Proteobacteria|Rep: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE DECARBOXYLASE - Brucella melitensis Length = 311 Score = 160 bits (388), Expect = 4e-38 Identities = 82/264 (31%), Positives = 148/264 (56%), Gaps = 4/264 (1%) Query: 18 GYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVD 77 G L+ D IVD++ S TL +++ G L ++ + + A +PLSS+T PI Sbjct: 39 GVLKEDGIVDLSARHGSRWPTLREVIEAGVLAQLAQEAAGLAADVPLSSITYEIPIPSPG 98 Query: 78 KILCIGLNYKDHCQE--QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 KI+C+G+N+ D +E P P +F +F + G ++P+ +R + ++D+E E+ Sbjct: 99 KIICVGVNFPDRNEEYKDGQAAPANPSLFVRFPRSFTGHERPL-MRPPESPQLDYEGEIA 157 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLT 195 +V+G+ + E+DAL H+A T+ + + RDW + GK+ D +GP ++ Sbjct: 158 IVIGKGGRRIAEKDALDHIAALTLCNEGTIRDWVRHAKFN-VTQGKNFDATGSIGPWLVP 216 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 + +++++ +NG ++Q T++++ S +++ +S+ TLVPGD+I+ GTP G Sbjct: 217 YTDESQIADIQLTTRVNGEVRQQDRTSRMIFSFRKIINYVSTFTTLVPGDVIVCGTPTGA 276 Query: 256 GMYRQPPEYLQPGDVLTSEIEKIG 279 G PP +L+PGDV+ E E IG Sbjct: 277 GARFDPPIWLKPGDVVEVEAEGIG 300 >UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9; Ascomycota|Rep: Degradation of aromatic compounds - Pichia stipitis (Yeast) Length = 293 Score = 159 bits (387), Expect = 6e-38 Identities = 80/219 (36%), Positives = 127/219 (57%), Gaps = 7/219 (3%) Query: 68 TLTAPI--HGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVT 125 TL P+ V + C+GLN+ H QE TPPP P +F K S ++ + + I Sbjct: 66 TLLGPLTPDDVPMVKCVGLNFMKHIQEGGRTPPPFPSIFYKTSFSVADFGEDIPIPKIAQ 125 Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK----NMGQFLLGK 181 K D+E ELC+V+G+ ++EE+AL +VAGY D+S+R+WQK+ ++ Q+ K Sbjct: 126 SKCDYEGELCIVIGKTGKNIKEEEALSYVAGYVTGNDVSSRNWQKDPEFAGSVPQWCFSK 185 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 S D + PLGP +++ + L + ++NG ++Q ++T L+ +P ++ IS TL Sbjct: 186 SFDKYAPLGPALVSPQVIQNPGNLSLQTTVNGEIRQDANTDDLLFGVPRIISFISQSTTL 245 Query: 242 VPGDLILTGTPGGVGMYRQP-PEYLQPGDVLTSEIEKIG 279 G +I+TGTP GV + +P P YLQ GDV+ I++IG Sbjct: 246 EMGTVIMTGTPSGVALGMKPTPVYLQNGDVVEVAIDQIG 284 >UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=7; cellular organisms|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Methanococcus maripaludis Length = 202 Score = 159 bits (387), Expect = 6e-38 Identities = 81/202 (40%), Positives = 130/202 (64%), Gaps = 13/202 (6%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+C GLNYKDH +E + P P++F K +S+II ++ ++I +++VD+E EL +V Sbjct: 7 KIVCAGLNYKDHAEELKMKLPKEPVIFLKPTSSIIYNEEAIKI-PKASERVDYEAELAIV 65 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +G+ V++ED ++ G+T+ D++ARD Q EK+ GQ+ KS DTF P+GP +++ Sbjct: 66 IGKTCKSVKKEDVKNYIKGFTILNDVTARDLQ-EKD-GQWTRAKSFDTFSPIGPKIVSGI 123 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 + A L++ +NG +KQ S+T ++ S+ L+ +SS+MTL PGD+I TGTP G+G Sbjct: 124 D---ANNLKIQLRVNGKIKQDSNTNNMIFSVEELVEFVSSIMTLYPGDIISTGTPPGIGK 180 Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279 L+ GD++ EIE IG Sbjct: 181 -------LEKGDIVEIEIENIG 195 >UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; n=1; Citrobacter koseri ATCC BAA-895|Rep: hypothetical protein CKO_03358 - Citrobacter koseri ATCC BAA-895 Length = 295 Score = 158 bits (383), Expect = 2e-37 Identities = 90/279 (32%), Positives = 146/279 (52%), Gaps = 10/279 (3%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60 MKL F Y+ + G + ++D+ L +L+ LE+ ++ P Sbjct: 9 MKLASFLYQGTRS---YGIVTAGGVIDLGNRIGDQYRDLKALLQGDGLEQARRFAQA-PV 64 Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 + + ++T I +KILC+G+NY + QE + P P +F +F+ + G + PV + Sbjct: 65 DLKMDAITFLPVIERPEKILCVGMNYAEKRQEFD-QHDPAPTLFVRFADSQTGHNMPV-L 122 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 + + + D+E EL V++G + + AL HVAGY+ D SARDWQ F G Sbjct: 123 KPRHSHEFDYEGELAVIIGNGGENISRDHALDHVAGYSCYMDGSARDWQHS----WFTAG 178 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 K+ GP ++T+DE+ +L + LNG + Q +T+ ++H + L+ IS+ Sbjct: 179 KNWRQTGAFGPWMVTADEIPDPHQLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTR 238 Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 L GD+I+TG+PGGVG R PP ++Q GD + EIE IG Sbjct: 239 LNSGDVIITGSPGGVGKKRNPPLFMQEGDRIEVEIEHIG 277 >UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 286 Score = 158 bits (383), Expect = 2e-37 Identities = 77/207 (37%), Positives = 121/207 (58%), Gaps = 2/207 (0%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 V+ ILC+GLNY+ H +E NL P P +F K S + GP + V I D +D+E EL Sbjct: 67 VNVILCVGLNYRRHAEECNLQIPENPAIFMKPSDALAGPLEDVPIHKDCQSMLDYEGELT 126 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM--GQFLLGKSMDTFCPLGPCV 193 +V+G++ V + +V GYTV D+SAR++Q N+ GQF KS D FCP+GPC+ Sbjct: 127 IVIGKDCKNVSAANFQDYVLGYTVGNDVSARNYQLPANVSGGQFGYAKSFDKFCPIGPCI 186 Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253 ++ + +L +NG +Q + T ++++I ++ +S TL G ILTGTP Sbjct: 187 ASTKVIPDPQKLTYWTKVNGEKRQETGTDDMIYTIGQVIEHLSRGTTLRAGTAILTGTPS 246 Query: 254 GVGMYRQPPEYLQPGDVLTSEIEKIGA 280 GVG++ +P +L+ GD + ++ IG+ Sbjct: 247 GVGLFMEPKNFLKDGDEVEIYVDGIGS 273 >UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=4; Burkholderiales|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 284 Score = 157 bits (381), Expect = 3e-37 Identities = 83/216 (38%), Positives = 130/216 (60%), Gaps = 4/216 (1%) Query: 65 SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDV 124 +++T P+ KILC+GLNY DH +E P P +F + ++++G D + +R Sbjct: 60 AALTWLPPVISPRKILCVGLNYADHTKESPYEQPDYPTLFLRVPTSMVGHDCAI-VRPLA 118 Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184 + +D+E EL VV+G+ + EDAL HV GY+V D S R++Q + Q+ +GK+ D Sbjct: 119 SDTLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVREYQFKSP--QWTVGKNFD 176 Query: 185 TFCPLGPCVLTSDEVG-AAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243 GP V+T+DE+ A LR+ LNG + QS+ST+ +++ + SL+ IS +TL P Sbjct: 177 ATGGFGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEP 236 Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 GD+I+ GTP G+G R+P ++ GDV IE+IG Sbjct: 237 GDVIVAGTPSGIGWAREPKLLMRHGDVCEVSIERIG 272 >UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Comamonas testosteroni KF-1 Length = 286 Score = 157 bits (381), Expect = 3e-37 Identities = 87/247 (35%), Positives = 132/247 (53%), Gaps = 8/247 (3%) Query: 38 TLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE----- 92 TL + + D + L A L+ VT I +KI+C NY DH QE Sbjct: 33 TLADFIASPDFARRDALTDGLAADAKLADVTFLPVIPRPEKIVCAVRNYMDHHQEVLAAG 92 Query: 93 QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQ 152 P +F + + P+ +R V+ +DWE EL V++G+ + E DA + Sbjct: 93 MQRELSEEPPIFLRVWRSQTAHQGPI-VRPHVSDSLDWEGELAVIIGQGGRDIAEADAWE 151 Query: 153 HVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLN 212 H+AGY+ D S R+WQ Q GK+ ++ GP ++T+DE+ EL++ LN Sbjct: 152 HIAGYSCYNDASVREWQFHAK--QIASGKNFESTGAFGPWMVTADEISPGRELKLETRLN 209 Query: 213 GVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLT 272 G + QSS T ++ SIP L+ S++ TLVPGD+I+TGTP GVG ++P ++++ GDV+ Sbjct: 210 GAVVQSSHTGHMIFSIPRLIAYASTIFTLVPGDVIITGTPAGVGWSKKPQQFMKAGDVVE 269 Query: 273 SEIEKIG 279 EIE IG Sbjct: 270 VEIEAIG 276 >UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; Staphylococcus|Rep: Uncharacterized protein SH1982 - Staphylococcus haemolyticus (strain JCSC1435) Length = 301 Score = 157 bits (381), Expect = 3e-37 Identities = 94/304 (30%), Positives = 160/304 (52%), Gaps = 21/304 (6%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSL------PTTLLQILR-NGDLEKVKK 53 MK + F+YKD+ ++ V D + D+ K + P TLL+ L+ N L+ ++ Sbjct: 1 MKFLSFNYKDA-ESYGVKVKRKDAVWDLKKVFAEFGEGDFHPQTLLEGLQQNQTLDFQEQ 59 Query: 54 LKSTKPAT----------IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMV 103 ++ A I + + P+ + ++ G NY+DH E N + V Sbjct: 60 VRKAVVAAEDSGKADEFKIAFNDIEFLPPVTPPNNVIAFGRNYQDHASELNHEVQRL-YV 118 Query: 104 FSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDI 163 F+K +S++ G + + D+T ++D+E EL +V+G+ + + AL ++ GYT+ DI Sbjct: 119 FTKAASSLTGDESTIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYIYGYTIINDI 178 Query: 164 SARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQ 223 + R Q E++ Q L KS+ CP+GP ++T DE+ + + +N ++Q +T+Q Sbjct: 179 TDRKAQNEQD--QAFLSKSLTGGCPMGPYIVTKDELPTPENVNIVTKVNNDIRQDGNTSQ 236 Query: 224 LVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDV 283 +++ I L+ IS + L PGD+I TGTP GVG QPP++LQPGD + I+ IG Sbjct: 237 MINKIDDLIEEISKYVALHPGDIIATGTPAGVGAGLQPPQFLQPGDEVKVTIDNIGTLTT 296 Query: 284 RIEK 287 I K Sbjct: 297 YIAK 300 >UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lmo2266 protein - Listeria monocytogenes Length = 282 Score = 157 bits (380), Expect = 4e-37 Identities = 93/290 (32%), Positives = 158/290 (54%), Gaps = 12/290 (4%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDD-IVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKP 59 MK + + Y+ ++ G L ++ I+ S+ P TLL ++ L V +L Sbjct: 1 MKWLSYLYEG---DLAYGILTPENKIIPAGTIFSNPPATLLDFIKEKPL--VPELTGID- 54 Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP--PPVPMVFSKFSSTIIGPDQP 117 I L+ V + P + I+ IG NY +H E P +VF+K +++++ + Sbjct: 55 GHIDLAEVEIQVPFVPPNNIIAIGKNYYNHVLEMGSKEDVPEHILVFTKSANSLLPHNGN 114 Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF 177 + + ++T ++D+E EL V++G + + E++AL + G+T+ DI+ARD QK+ QF Sbjct: 115 IELHQNITGQLDYEGELAVIIGEKVRDISEQEALSAIFGFTILNDITARDLQKKHK--QF 172 Query: 178 LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237 LGKS+D CP+GP VL ++ V + +NG ++QS ST + + + ++ +S Sbjct: 173 YLGKSLDASCPIGPFVLENNANKEPV-FHIETKVNGEVRQSDSTDKFIFGLARIISDLSK 231 Query: 238 VMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 TL+PGD+I TGTP GVG PP +LQ GD++ I+KIG ++ K Sbjct: 232 GHTLLPGDIIATGTPSGVGNGMTPPTFLQDGDIIEITIDKIGTLTNKVRK 281 >UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Fumarylacetoacetate hydrolase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 285 Score = 157 bits (380), Expect = 4e-37 Identities = 87/223 (39%), Positives = 125/223 (56%), Gaps = 6/223 (2%) Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVP---MVFSKFSSTIIGPDQ 116 A +P VTL P+ K++CIGLNY H E + P+P +F+++ ST+ Sbjct: 50 AVLPRDEVTLVPPVLPGAKVICIGLNYLKHVAEGSYGAEPLPEFPTLFARWPSTLTVDGA 109 Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176 + + TD + +DWE E+ VGRE SC ++AL V GY+ D++AR + +K Q Sbjct: 110 QIPVPTD-EEGLDWEGEVVAWVGRELSCATADEALDAVVGYSTFNDVTAR--RAQKITSQ 166 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 ++LGK+ D PLGP V D LRV +NG Q +ST ++V+++ L IS Sbjct: 167 WILGKNADRSGPLGPLVPAHDVGDLRDGLRVRTRVNGTTVQDASTDEMVYTVGETLAHIS 226 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +TL PGDL+ TGTP GVG R P L PGD + E+EK+G Sbjct: 227 RTLTLRPGDLLATGTPSGVGYARTPAWLLHPGDHVEVEVEKLG 269 >UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 356 Score = 156 bits (379), Expect = 5e-37 Identities = 83/215 (38%), Positives = 120/215 (55%), Gaps = 3/215 (1%) Query: 65 SSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDV 124 SS+T P+ DKI+ +G NY+ H E P P +F +F S+ +G QPV + + Sbjct: 127 SSLTFLPPVTDPDKIIAVGFNYRGHLIETGTPLPDYPSLFVRFPSSQVGHGQPV-VAPSL 185 Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMD 184 + + D+E EL V++GR A V E DA+ HV GY+ + S RD+Q Q GK+ Sbjct: 186 SGEFDFEGELAVIIGRPAWRVAEADAMDHVVGYSCFAENSVRDYQAHAR--QVTAGKNFL 243 Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244 +GP + T+DEVG L ++ LNG + Q L+ +IP L+ I+ L+PG Sbjct: 244 ASGAIGPWLTTADEVGDPSTLELTTRLNGAVVQQDRLTSLIFTIPQLIAYITRFTRLLPG 303 Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 D+I TGTP GVG R P +L PGDVL +I ++G Sbjct: 304 DIISTGTPDGVGFLRDPKIWLAPGDVLEIDIPRVG 338 >UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Oceanicola batsensis HTCC2597|Rep: Fumarylacetoacetate hydrolase family protein - Oceanicola batsensis HTCC2597 Length = 252 Score = 156 bits (379), Expect = 5e-37 Identities = 91/225 (40%), Positives = 129/225 (57%), Gaps = 16/225 (7%) Query: 56 STKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPD 115 ST +PLS V L P+ K++C+GLNYK H +E P PM+F S +I PD Sbjct: 34 STTEDRLPLSDVALLPPVEP-GKLVCVGLNYKRHAEESGAAIPEEPMLFMCAPSAVI-PD 91 Query: 116 QPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMG 175 + ++D+E E+ +V+G++A + E DA + GYT+ D+S RD+QK+ G Sbjct: 92 GGTILLDSQDARIDYEAEIAIVIGKQARNLPEADARSCIFGYTICNDVSNRDYQKKD--G 149 Query: 176 QFLLGKSMDTFCPLGPCVLTS-DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234 QF KS DT+ PLGP + T D AA+ LR NG L+Q S+T+ ++ SI ++ Sbjct: 150 QFTRAKSFDTYKPLGPWIETGLDPDNAAISLRQ----NGELRQQSNTSDMIFSIDRIVAF 205 Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +S +MTL PGD+I+TGTP GVG R GD + EIE IG Sbjct: 206 VSGIMTLNPGDVIITGTPEGVGPMRS-------GDRIEIEIEGIG 243 >UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=6; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 292 Score = 155 bits (377), Expect = 9e-37 Identities = 93/284 (32%), Positives = 151/284 (53%), Gaps = 8/284 (2%) Query: 1 MKLVQFSYKDSPK-NIRVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKST 57 MKLV F DS VG+ +VD+++ +P+ + +L G L + ++ + Sbjct: 1 MKLVTFRTSDSVSWGAVVGHDSASGVVDLSRRLPDVPS-VKSLLSGGASLLARAREALAG 59 Query: 58 KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE--QNLTPPPVPMVFSKFSSTIIGPD 115 PLSSV L P+ G +KI CIG+NY E N P P VF + +++ G Sbjct: 60 VQVDHPLSSVQLLPPVLGPEKIFCIGVNYAHRNAEYKDNSDLPKYPSVFMRTPASLTGHG 119 Query: 116 QPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMG 175 QP+ + + +K++D+E E+ +V+G+ + +EDA H+AG T + + RDW Sbjct: 120 QPLLLPPE-SKQLDYEGEIGIVIGKAGRRIAKEDAHTHIAGLTCINEGTIRDWLHHGKFN 178 Query: 176 QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235 GK+ D +GP ++T+DE + ++ +NG ++Q +TA L+ SL+ + Sbjct: 179 -VTQGKNFDASGAIGPWIVTADEFPDFDNIGLTTRVNGEVRQQDTTANLMFPFASLISYL 237 Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 S TL PGD+I TGTP G G+ PP +L PGDV+ E++ +G Sbjct: 238 SQFATLNPGDIIATGTPIGAGVRFDPPRFLVPGDVVEVEVDGVG 281 >UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase; n=1; Thermoplasma acidophilum|Rep: Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase - Thermoplasma acidophilum Length = 315 Score = 155 bits (377), Expect = 9e-37 Identities = 90/293 (30%), Positives = 155/293 (52%), Gaps = 16/293 (5%) Query: 1 MKLVQFSYKDSPKN-IRVG-----YLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKL 54 +K++ F KD P + +G + E I D+ K+ + D++ + + Sbjct: 30 LKILNFLDKDGPAGGVLLGDTLYPFAELSKISDVFKSFQITDDVIASNADQNDIDMIVEE 89 Query: 55 KSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP 114 +K P+++ + AP+ KILCIG+NY +H +E P +F KF +IIG Sbjct: 90 SKSKLRGRPIATTKILAPVLRSGKILCIGVNYMEHAKESRQKVMEHPTIFCKFQDSIIGN 149 Query: 115 DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM 174 + + D K++D+E EL V++GR + + GYT+ D+SARD Q + Sbjct: 150 MDDITVPKDA-KQIDYEGELVVIIGRSSGTAESS-----IFGYTIGNDVSARDLQFRTS- 202 Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234 Q+LLGK++ TF P+GP ++ +E+G A +L++ +NG ++Q+ +T+ ++ + +++ Sbjct: 203 -QWLLGKALPTFAPIGPVIVGKNELGFARDLQIITRVNGTVRQNGNTSDMIFDVRAIVDY 261 Query: 235 ISSVMTLVPGDLILTGTPGGV--GMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 +S L PGD+I TGTP GV G+ +L+ GDV+ I IG RI Sbjct: 262 LSGYFNLGPGDIIFTGTPEGVILGLPENERVWLKHGDVIDVSITGIGTLTNRI 314 >UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Picrophilus torridus|Rep: Fumarylacetoacetate hydrolase family protein - Picrophilus torridus Length = 281 Score = 155 bits (377), Expect = 9e-37 Identities = 83/216 (38%), Positives = 128/216 (59%), Gaps = 4/216 (1%) Query: 73 IHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEV 132 I +KI+C+G NYK+H E P P++FSKF++T+ G + I D + +D+E Sbjct: 68 ISNPEKIICVGKNYKEHALETGSGIPESPVLFSKFNNTLTGHLNDIII--DFSDSIDYEG 125 Query: 133 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPC 192 EL +V+G++A V E DA+ +V GY +A D+SARD Q + Q+LLGK+ D F P GP Sbjct: 126 ELGIVIGKKARNVDENDAMDYVFGYYIANDVSARDLQYRTS--QWLLGKTPDGFYPNGPF 183 Query: 193 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252 ++T DEV + L + NG Q S+T ++ I L+ IS +TL+PGD+I TGTP Sbjct: 184 IVTKDEVNDPMNLDIRTLRNGDTVQHSNTRNMIFDIKYLIGYISKYLTLMPGDVISTGTP 243 Query: 253 GGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288 GV + +++ + + +IEK+G+ R K+ Sbjct: 244 EGVILGTNEKNWIKNNETIEVKIEKLGSLKNRFIKY 279 >UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase; n=1; Cenarchaeum symbiosum|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase - Cenarchaeum symbiosum Length = 288 Score = 155 bits (376), Expect = 1e-36 Identities = 90/246 (36%), Positives = 133/246 (54%), Gaps = 5/246 (2%) Query: 35 LPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQN 94 LPT L L G L +V LS + API KI C+ NY DH Q+Q+ Sbjct: 36 LPTRLGGFLFEGWLAEVNDRLDGLEYERGLSEYGIMAPIAEPPKIFCLAFNYADHAQDQD 95 Query: 95 LTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHV 154 +PP P++ K + + G + + K++D+EVEL +++G+ V A + + Sbjct: 96 RSPPDEPVIVMKPRTALCGNGDDI-VMPPFVKELDYEVELALIIGKRCRDVDVIGAKEAI 154 Query: 155 AGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGV 214 GYT+ D+SARD Q GQF K +DTF P GP + ++DEV L+++ +NG Sbjct: 155 FGYTILNDVSARDIQFRD--GQFTRAKGLDTFAPCGPWITSADEVQDPGRLKMTTKVNGR 212 Query: 215 LKQSSSTAQLVHSIP-SLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTS 273 +Q SST+++ H P ++ ++SS MTL GD+I TGTP GV + EYL GD + Sbjct: 213 ARQDSSTSKM-HIKPFEIVSKLSSSMTLEKGDIISTGTPSGVALNNPDSEYLAAGDEIEM 271 Query: 274 EIEKIG 279 EIE +G Sbjct: 272 EIEGLG 277 >UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; cellular organisms|Rep: Uncharacterized protein AF_2225 - Archaeoglobus fulgidus Length = 250 Score = 155 bits (375), Expect = 2e-36 Identities = 88/218 (40%), Positives = 130/218 (59%), Gaps = 14/218 (6%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 +PL++V P+ KI+ +GLNY DH +E N+ P P++F K S+ +IG D + I Sbjct: 30 VPLTAVKFLPPVVP-SKIIAVGLNYIDHAEELNMPVPEEPILFMKPSTAVIGHDDCI-IL 87 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 ++++VD+E EL VV+ + V E +A ++ GYT D++ARD Q + GQ+ K Sbjct: 88 PQISQRVDYEGELAVVIAEDCRNVPETNAADYILGYTCFNDVTARDLQAKD--GQWTRAK 145 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 S DTF PLGP + D+ +L + +NG + Q S+T+ L+ + L+ +SSVMTL Sbjct: 146 SFDTFAPLGPYIAEIDDPS---KLGIQTRVNGKVVQKSNTSNLIFDVFQLVSFVSSVMTL 202 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 GD+I TGTP GVGM L+ GDV+ EIEKIG Sbjct: 203 KAGDVIATGTPAGVGM-------LKDGDVVEVEIEKIG 233 >UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Desulfitobacterium hafniense|Rep: Fumarylacetoacetate (FAA) hydrolase - Desulfitobacterium hafniense (strain DCB-2) Length = 251 Score = 154 bits (374), Expect = 2e-36 Identities = 84/213 (39%), Positives = 130/213 (61%), Gaps = 14/213 (6%) Query: 67 VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126 V L AP+ KI+CIGLNY H +E P++F K ++++GP+ + I +++ Sbjct: 46 VRLLAPVEPT-KIVCIGLNYAKHIEELGHDFHDDPVIFLKPVTSLVGPEDEI-ILPAMSQ 103 Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 186 +VD+E EL VV+G+ A + E+ A ++ G+T D++ARD QK+ GQ+ K DTF Sbjct: 104 QVDYEAELVVVIGKTAKDLAEDQAEDYIFGFTCGNDVTARDLQKKD--GQWTRSKGFDTF 161 Query: 187 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 246 CP+GP ++ + +++ LNG +KQSS T+ L+HS+P L+ IS +MTL PGDL Sbjct: 162 CPIGPWIVRDLDYR---NVKIRSVLNGEVKQSSQTSHLIHSVPKLVSYISKIMTLNPGDL 218 Query: 247 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 I+TGTP GVG ++ GD + +I+ IG Sbjct: 219 IMTGTPEGVGP-------MKTGDAIAIDIKGIG 244 >UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1; Streptomyces ambofaciens ATCC 23877|Rep: Putative maleylpyruvate isomerase - Streptomyces ambofaciens ATCC 23877 Length = 288 Score = 153 bits (371), Expect = 5e-36 Identities = 103/278 (37%), Positives = 149/278 (53%), Gaps = 22/278 (7%) Query: 16 RVGYLEGDDIVDINK----ADSSLPTTLLQ--ILRNGDLEKVKKLKSTKPATIPLSSVTL 69 R+G ++GDD+VD+ A ++ P +Q I E V+ + +P T PL+ L Sbjct: 10 RLGVVDGDDLVDVTDQLTGAGTAGPAGAVQRYIETTARGEAVRFDLAGRPRT-PLAEAAL 68 Query: 70 TAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPM-VFSKFSSTIIGPDQPVRIRTDVTKKV 128 AP+ KI+ +NY DH E T + VF K +S++IGP + + + K+ Sbjct: 69 QAPLPLPGKIIGAPVNYLDHKAEMEYTTSVADLGVFLKANSSVIGPGEDILLPYS-DKRT 127 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188 D E EL VV+GR A+ V +DAL HV GYT DI+ R + KS DTF P Sbjct: 128 DQEGELGVVIGRTAAHVSADDALGHVFGYTCVLDITVRSGEDRSTR------KSFDTFTP 181 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 LGP V+T+DE+ L + C + G +Q ++TA L+ + L+ SSVMTL PGD+I Sbjct: 182 LGPWVVTADEIPDPDTLDLRCDVGGTTRQRTNTADLIFGVRELIAYTSSVMTLHPGDVIA 241 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286 TGTP GVG L GD + +IEK+G +V ++ Sbjct: 242 TGTPAGVGP-------LAHGDRVVLDIEKVGRLEVGVD 272 >UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 274 Score = 152 bits (369), Expect = 9e-36 Identities = 73/194 (37%), Positives = 121/194 (62%), Gaps = 3/194 (1%) Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK-KVDWEVELCVV 137 + CIGLNYK+H E +T P P VF K ++ I +P+ + + V + D+EVEL ++ Sbjct: 65 VRCIGLNYKEHAAEMKMTLPDAPTVFLKANTCISSAAEPIVLPSVVDHDEADYEVELAII 124 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +G+ V +A+ +V GY+VA D++AR Q + + Q+ K MD FCPLGPC+++++ Sbjct: 125 IGQRCKNVSVAEAMGYVLGYSVANDVTARKHQGKTS--QWSYAKGMDGFCPLGPCIVSAE 182 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 ++ ++ SLNG Q++S ++ SI ++ +S TL+PG +I+TGTP G+G+ Sbjct: 183 KIPDPSVFQLRTSLNGKTMQNASADDMIFSIAEVVSYLSQGHTLLPGTVIITGTPCGIGV 242 Query: 258 YRQPPEYLQPGDVL 271 + PP +L+PGD L Sbjct: 243 SQNPPVFLKPGDRL 256 >UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Methylobacterium sp. 4-46|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Methylobacterium sp. 4-46 Length = 288 Score = 152 bits (368), Expect = 1e-35 Identities = 89/262 (33%), Positives = 145/262 (55%), Gaps = 8/262 (3%) Query: 23 DDIVDINKADSSLPTTLLQILRNGD--LEKVKKLK--STKPATIPLSSVTLTAPIHGVDK 78 D + D+ D LP + ++ G +++ KK +T A + S+ I K Sbjct: 20 DGLYDLRMVDPGLPDGVGGLVAGGPEFMDRAKKAAGAATGAARLDEGSLRYRPLIERPGK 79 Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138 I+CIG NY H +E P P VF + +++++ +P+ IR + K D+E EL VV Sbjct: 80 IICIGRNYAAHAREGGAEPLDYPDVFMRGANSLVAHGEPL-IRPRCSDKFDYEGELVFVV 138 Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE 198 GR+A V ++A +AGY+V + S RD+Q+ Q+ +GK+ D GP ++T DE Sbjct: 139 GRKARHVGLDEACGIIAGYSVFNEGSIRDYQRRAT--QWTMGKNFDGTGGFGPDLVTPDE 196 Query: 199 VGAAVE-LRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 + + LR++ +LNG + Q +T + + ++ ++ MTL PGD++LTGTP GVG Sbjct: 197 LPDGADGLRLTTTLNGHVMQDGNTHDFIFPVARIVAILTEAMTLEPGDVVLTGTPSGVGY 256 Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279 R PP +++PGDV+ IEK+G Sbjct: 257 ARNPPVFIKPGDVVEVTIEKVG 278 >UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 250 Score = 151 bits (367), Expect = 2e-35 Identities = 89/218 (40%), Positives = 126/218 (57%), Gaps = 14/218 (6%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 +PL L AP KI+C+G NY DH E P P++F K +T+ P+ V Sbjct: 40 LPLEQCRLLAPCEPT-KIICVGKNYYDHAMEMGEGVPDRPILFIKAPNTVNHPEGEVSA- 97 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 D +++D+E EL VV + A V+ E+ ++ GYT D++ARD QK GQ+ GK Sbjct: 98 PDFVERLDYEGELAFVVKKRAKNVKAEEYGDYILGYTCLNDVTARDIQKSD--GQWSRGK 155 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 SMD F P+GP L +DEV + +L++ LNG QSS T+ + IP+L+ I++ MTL Sbjct: 156 SMDGFAPIGP--LVTDEVDGS-DLKIETRLNGKTVQSSRTSLFMTKIPALMEFITASMTL 212 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 PGD++ TGTP G+G +QPGDV+ EIE IG Sbjct: 213 EPGDVVTTGTPAGIGA-------MQPGDVVEVEIEGIG 243 >UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Planctomyces maris DSM 8797|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Planctomyces maris DSM 8797 Length = 310 Score = 151 bits (367), Expect = 2e-35 Identities = 88/234 (37%), Positives = 135/234 (57%), Gaps = 15/234 (6%) Query: 59 PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE----QNLTPPPVPMVFSKF-SSTIIG 113 P +I V L P+ K+L + NY H +E P VF K S+T+ Sbjct: 72 PLSIQTDEVQLLVPVPEPSKLLLLAGNYSKHIEEGGGKAEERQKTFPYVFMKPPSTTLTH 131 Query: 114 PDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ---- 169 P QPV+I +DWE+EL +V+G+ V E +AL +VAGYTV DIS R ++ Sbjct: 132 PGQPVKIPEVSPDYIDWELELGIVIGKSCKGVSEAEALDYVAGYTVINDISDRKFRPNPG 191 Query: 170 ---KEKN-MGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLV 225 +EK+ + GK DTFCP+GPCV +D++ L++ S+NG ++Q +STA+++ Sbjct: 192 RTLREKDTFFDWQHGKWHDTFCPMGPCVTPADDIPDPQTLKMKLSVNGNVEQDASTAEMI 251 Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + +++ ISS + L PGD+I TGTP GVG + ++L+ GDV+ +EI++IG Sbjct: 252 FPVAAIVEFISSFVQLEPGDVISTGTPSGVGASKN--KFLKNGDVMKAEIDQIG 303 >UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584; n=2; Vibrio|Rep: Putative uncharacterized protein VV1584 - Vibrio vulnificus (strain YJ016) Length = 259 Score = 151 bits (366), Expect = 2e-35 Identities = 80/222 (36%), Positives = 124/222 (55%), Gaps = 9/222 (4%) Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 ++P T +PI I +GLNY DH E PP P+VF K ++T+ QP Sbjct: 30 SLPAGQFTWLSPIENPGTIFALGLNYADHASELAFEPPKEPLVFLKGANTLTAHQQPSYR 89 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 D+ + + +E EL VVG+EA V+ EDA+ ++ G+T+ D + RD+ E L Sbjct: 90 PNDI-EFMHYECELVAVVGKEARNVKREDAMDYIQGFTICNDYAIRDYL-ENYYRPNLRV 147 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 KS D+ CP+GP ++ D++ L ++ +NG L Q +T+ ++ +P L+ +SS MT Sbjct: 148 KSRDSLCPIGPWIVDCDDIEDVNNLALTTHVNGELTQQGNTSDMIFDVPFLIEYLSSFMT 207 Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 L PGDLI TGTP G+ + +QPGDV+ IE +G+ + Sbjct: 208 LKPGDLIATGTPKGL-------KDIQPGDVVRCTIEGVGSLE 242 >UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Methylobacterium sp. 4-46|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Methylobacterium sp. 4-46 Length = 480 Score = 151 bits (366), Expect = 2e-35 Identities = 94/274 (34%), Positives = 147/274 (53%), Gaps = 15/274 (5%) Query: 25 IVDINKADSSL----PTTLLQILRNGD---LEKVKKLKSTKPATIPL--SSVTLTAPIHG 75 I+D+ A +SL P + +L+NG L V + P T+ L +V + Sbjct: 208 ILDVTAAAASLGLPAPADMDDLLQNGKGGLLRAVADGAARGPDTLYLREEAVRFAPLVTR 267 Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 +KI+ +G NY+ H E P P +F+K+++ + +++ T V ++ D+EVEL Sbjct: 268 PEKIIMMGFNYRHHAAETGTPIPKDPPLFNKYNNALNHHGGTIKLPTAVAREFDYEVELV 327 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLT 195 +V GRE S V E +AL VAGY D SARD Q + QF++GK+ D F PLGP ++T Sbjct: 328 IVFGRECSNVSEAEALDCVAGYATGNDFSARDLQTLTS--QFMIGKTADGFAPLGPYLVT 385 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 SD V LR+ +NGV +Q +T ++ + L+ S +MT+ PGD+ TGTP GV Sbjct: 386 SDLVKDPNNLRLETRVNGVQRQDWNTNDMIFNCRQLISFASKMMTIKPGDIFYTGTPHGV 445 Query: 256 GMYRQPP----EYLQPGDVLTSEIEKIGAFDVRI 285 + P ++L+PGD + +E +G R+ Sbjct: 446 IFGEKKPRAERQWLKPGDEVACSLEGLGELRFRL 479 >UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG11179.1 - Gibberella zeae PH-1 Length = 281 Score = 151 bits (365), Expect = 3e-35 Identities = 81/208 (38%), Positives = 122/208 (58%), Gaps = 6/208 (2%) Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP-DQPVRIRTDVTK-KVDWEVELCV 136 ++CIGLNY DH +E + P VP+VF K + + GP D V T K ++D+E EL + Sbjct: 66 VVCIGLNYTDHAEEAQMPIPKVPVVFFKPVTALAGPHDDLVLPHTSWEKGRLDYESELVI 125 Query: 137 VVGREASCVREEDALQHVAGYT--VAQDISARDWQKEKNMG--QFLLGKSMDTFCPLGPC 192 V+G++AS V ++DAL +V YT DIS R WQ + +G Q+ K D P+GP Sbjct: 126 VIGKKASRVSKDDALDYVFSYTFHAGNDISNRAWQLDPQLGGGQWCYSKCFDCSAPIGPA 185 Query: 193 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252 +++ D +G+AV L + +LN Q +T ++ + ++ +S MTL+PG I TGTP Sbjct: 186 IVSKDILGSAVGLGIRGTLNDTQSQDGNTNNMIFGVAEIVSFLSQGMTLLPGTFIFTGTP 245 Query: 253 GGVGMYRQPPEYLQPGDVLTSEIEKIGA 280 GVG ++P ++ GDV EI+ IGA Sbjct: 246 AGVGFGKKPQISVKEGDVTQVEIDGIGA 273 >UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Desulfovibrio|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Desulfovibrio desulfuricans (strain G20) Length = 264 Score = 150 bits (364), Expect = 4e-35 Identities = 87/208 (41%), Positives = 120/208 (57%), Gaps = 12/208 (5%) Query: 72 PIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWE 131 P+ KI+C+G+N++DH +E P P+ F K SS +IG QPV + + + +V+ E Sbjct: 44 PVVTPSKIVCVGMNFRDHAEEIGFPVPEEPVFFLKPSSAVIGSGQPVVLPAE-SGRVEHE 102 Query: 132 VELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGP 191 EL VV+GR A + ED HV GYT A D++ARD Q G F K DTF P+GP Sbjct: 103 AELGVVIGRAARNITPEDVPAHVFGYTCANDVTARDLQSRD--GLFGRCKGFDTFAPVGP 160 Query: 192 CVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGT 251 + T EV L + +NG L+Q STA ++ S ++ +S VMTL+PGDLILTGT Sbjct: 161 WIET--EVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGT 218 Query: 252 PGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 P GVG L+ GD + EI+ +G Sbjct: 219 PAGVGP-------LEDGDEVRVEIDGVG 239 >UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Clostridium beijerinckii NCIMB 8052 Length = 294 Score = 149 bits (361), Expect = 8e-35 Identities = 83/251 (33%), Positives = 143/251 (56%), Gaps = 11/251 (4%) Query: 38 TLLQILRNGDLEKVKK-LKSTKPATIPLSSVTLTAPIHGVDK-ILCIGLNYKDHCQE--- 92 +L++ + + +++ ++K L + I + +++ PI ++ I+C+G+NY +H E Sbjct: 39 SLIENITDHEMDLLQKSLTNNDKEYISIENISKMPPIPNPNQDIICLGINYMEHAVESAR 98 Query: 93 -QNLT---PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREE 148 +N P + FSK +T + + +D+E EL V++G++A V +E Sbjct: 99 YKNEAFGGDRPYAVYFSKRVNTATADGDYIPSYPQIVDSLDYEAELAVIIGKDAKDVPKE 158 Query: 149 DALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVS 208 A +V GYT+ D+SAR+ Q Q+ GKS+D F P+GPC++T +E LR+ Sbjct: 159 KAFDYVFGYTIINDVSARNLQTRHK--QWYFGKSLDGFTPMGPCIVTKNEFVNPPVLRIC 216 Query: 209 CSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPG 268 +NG L+Q+S+T ++ SI ++H +S +TL G +I GTP GVGM PP++L+ G Sbjct: 217 SRVNGELRQNSTTDLMITSIQDVIHELSQGITLKVGTIIAMGTPAGVGMGFIPPKFLKTG 276 Query: 269 DVLTSEIEKIG 279 D++ EIE IG Sbjct: 277 DIVECEIEGIG 287 >UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Hyperthermus butylicus DSM 5456|Rep: Fumarylacetoacetate (FAA) hydrolase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 338 Score = 149 bits (361), Expect = 8e-35 Identities = 79/239 (33%), Positives = 134/239 (56%), Gaps = 2/239 (0%) Query: 47 DLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSK 106 +LE + ++ S+ +PLS+V L AP+ +KI+CIG+NY+ H +E + P P +F K Sbjct: 90 ELEGLARVVSSSDRGLPLSAVRLLAPVDKPEKIICIGVNYRAHARESGVELPGTPNLFVK 149 Query: 107 FSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISAR 166 ++I+GP PV + + V K+D EVEL V+G A + +A V G+ V D+++R Sbjct: 150 TGNSIVGPGDPVVVHS-VGLKLDGEVELAAVIGIPARSIPPSEAPDVVWGFMVLNDVTSR 208 Query: 167 DWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVH 226 Q+E + Q+ KS DT+ P GP ++ V + + ++G++ + +T +VH Sbjct: 209 LEQRELGISQWWRAKSHDTYAPTGPIIVPRHMVSIG-DTELELVVDGIVARRGNTGDMVH 267 Query: 227 SIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 S+ ++ S+ LVPGD+I TGTP G +P + +PG V+ + IG + R+ Sbjct: 268 SVWDIVSVASTSALLVPGDIICTGTPAGTMPDGKPAKTPEPGSVMRACARGIGCIENRV 326 >UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Burkholderiaceae|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 306 Score = 149 bits (360), Expect = 1e-34 Identities = 83/227 (36%), Positives = 125/227 (55%), Gaps = 11/227 (4%) Query: 63 PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPP----VPMVFSKFSSTIIGPDQPV 118 PL+ L P + +I NY +H +E P P +F K ++++ P Sbjct: 78 PLAGYRLRVP-YAPRRIFAAASNYYEHAREMGTELAPREESTPYMFMKAETSVV-PTLAE 135 Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMG--- 175 + ++VDWEVEL VV+G+ + DA +VAGYT+ D+SARD + + Sbjct: 136 VVMPPHAERVDWEVELAVVIGKPGRHIAVADAFDYVAGYTILNDVSARDLNRRTDYPFKH 195 Query: 176 QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235 + GKS DTF PLGP ++ + LR+ ++NG + Q +T +++ SI +H + Sbjct: 196 DWFRGKSFDTFGPLGPWLVPRACIAEPQNLRMRLAVNGEMMQDGNTGEMIFSIAEQIHYL 255 Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 SS++TL PGDLI TGTP GVGM R YLQPGDV+ + I+ IG+ + Sbjct: 256 SSILTLQPGDLIATGTPTGVGMGR--GIYLQPGDVMVASIDGIGSIE 300 >UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Caulobacter sp. K31|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Caulobacter sp. K31 Length = 293 Score = 147 bits (356), Expect = 3e-34 Identities = 92/284 (32%), Positives = 147/284 (51%), Gaps = 11/284 (3%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKLKSTK 58 M+L+ F +P VG G++++D+ A LP + +L G L ++ + Sbjct: 1 MRLLSFELNGAPA---VGVRLGEEVIDLGAAAPDLPRDIQALLAAGPEALAAAERAAAAA 57 Query: 59 P--ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ 116 P A PL+ V PI DKI+ +G Y H E P +F + +++ +Q Sbjct: 58 PGHARHPLAGVRHLVPIPRPDKIIGLGKTYMKHVAEMKAESSSFPGMFLRVPDSLVAHNQ 117 Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176 P+ R + + +D+E EL VV+G+ + E+AL+HVAGY D S R + + Sbjct: 118 PIW-RPEASDTLDYEGELMVVIGQGGRMISRENALKHVAGYACHNDGSVRAYNYIPSA-- 174 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVE-LRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235 GK+ GP ++T+DE+ + LR++ +NG L+QS+ A+L + L+H + Sbjct: 175 VTAGKNFLNTGGFGPEIVTADELPPGCKGLRLTTHVNGDLRQSADVAELHWDVAHLVHLM 234 Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 S++ TL PGDLI TGTP G P++L PGDV+ EIE +G Sbjct: 235 STIFTLYPGDLIATGTPSGCAAASANPQWLVPGDVVRVEIEGVG 278 >UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; Filobasidiella neoformans|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 336 Score = 147 bits (355), Expect = 4e-34 Identities = 88/283 (31%), Positives = 160/283 (56%), Gaps = 13/283 (4%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDD--IVDINKADSSLPTTLLQILRNGDLEKVKKLKSTK 58 MK V + + P+ I VG ++ + + ++ D++L T+ Q++ D L Sbjct: 18 MKFVSYRSRLHPQGI-VGLVDSTEQFVAPLSFPDNTLVRTMQQLIEEWDATHRHLLHGAP 76 Query: 59 PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVP--MVFSKFSSTIIGPDQ 116 ++ + V + AP+ G D ++C+G NY++H + V ++F+K +++IIG +Q Sbjct: 77 MESLDI--VEILAPLRGRD-VICVGKNYREHAEWVRSLFKLVKYVVIFTKRATSIIGTNQ 133 Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176 + VT+ +D+E EL +++G+ + EDA +V G T+ D++AR+ Q++ Q Sbjct: 134 EIYPHPRVTQTLDYEGELGIIIGKAGIQISREDAWDYVWGATIINDVTARERQRDHK--Q 191 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 F +GKS+DTFCP+GP + S + + + +NG ++QS++T+QL+ IP+L+ S Sbjct: 192 FYIGKSLDTFCPMGPYAVHSSVLDWR-NMMLETRVNGQIRQSANTSQLIFDIPALIATCS 250 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +TL PGD+I TGTP GV + E+L+ DV+ + +G Sbjct: 251 MGITLQPGDVISTGTPAGVCL--SSGEFLKHRDVIDISMSGLG 291 >UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Thermococcaceae|Rep: Uncharacterized protein PH0643 - Pyrococcus horikoshii Length = 230 Score = 146 bits (354), Expect = 6e-34 Identities = 85/213 (39%), Positives = 121/213 (56%), Gaps = 13/213 (6%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+ + NY +H +E PP P++F K S +IGP + I +K+VD EVEL V+ Sbjct: 22 KIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSI-ILPRRSKRVDHEVELAVI 80 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKE--KNMGQFLLGKSMDTFCPLGPCVLT 195 +G+ A V A ++ GYT+ DI+ARD Q E K + + K DTF P+GP V+ Sbjct: 81 MGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISKGFDTFAPIGPRVVD 140 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 S E+ + +L + +NG ++Q T+Q++ IP L+ IS +MTL PGD+I TGTP GV Sbjct: 141 SRELDPS-DLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLEPGDIIATGTPPGV 199 Query: 256 GMYRQPPEYLQPGDVLTSEIEKIG--AFDVRIE 286 G R GD + + IE IG FDV E Sbjct: 200 GPLRH-------GDRIEAWIEGIGKMEFDVLAE 225 >UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Acidobacteria bacterium Ellin345|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Acidobacteria bacterium (strain Ellin345) Length = 263 Score = 146 bits (353), Expect = 8e-34 Identities = 78/200 (39%), Positives = 116/200 (58%), Gaps = 6/200 (3%) Query: 58 KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP 117 +P + L L A + KI+C+G NYK H +E P P++FSK +S II P Sbjct: 44 EPLHVLLEEAELLASVVPT-KIVCVGRNYKAHAEELGHEIPKYPLIFSKPTSAIIAPGAD 102 Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREE-DALQHVAGYTVAQDISARDWQKEKNMGQ 176 ++ ++++VD+E EL V++GRE + E+ D ++ GYTV D++ARD Q + GQ Sbjct: 103 IKRPAKLSQRVDYEGELGVIIGRECRHIPEDHDVRSYIHGYTVVNDVTARDLQNKD--GQ 160 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 + K DTFCP+GP V +D + + V +NG ++Q +T+ + + +L IS Sbjct: 161 WTRAKGFDTFCPVGPIV--NDALDPWTGVEVETRVNGAVRQHGNTSSFIFPLDVILRFIS 218 Query: 237 SVMTLVPGDLILTGTPGGVG 256 VMTL PGDLI TGTP GVG Sbjct: 219 EVMTLFPGDLIATGTPEGVG 238 >UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase; n=2; Actinomycetales|Rep: Possible fumarylacetoacetate hydrolase - Rhodococcus sp. (strain RHA1) Length = 281 Score = 145 bits (352), Expect = 1e-33 Identities = 79/230 (34%), Positives = 123/230 (53%), Gaps = 5/230 (2%) Query: 51 VKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSST 110 V + + + I ++ V++ P+ +++C+GLNYK H E TPPP P +F +++ + Sbjct: 41 VARAEHLESPEIDVTLVSVVPPVPDSARVICVGLNYKAHAAEGGFTPPPYPTLFGRWTPS 100 Query: 111 IIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170 + P + + +DWE E+ +G V V GY D++AR + Sbjct: 101 LSVDGAPTPVPANEAG-LDWEGEVAAFIGTRLESVDAATGQAGVLGYACFNDLTAR--KA 157 Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVE-LRVSCSLNGVLKQSSSTAQLVHSIP 229 +K Q+ LGK+ D PLGP V + EVG + LRV +NG + Q +T L+ S+ Sbjct: 158 QKLTAQWTLGKNGDRSGPLGPLV-PAGEVGDLSDGLRVQTRVNGTVVQDGNTRDLIFSVG 216 Query: 230 SLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 ++ +S TL PGD+I TGTP GVG R PP L PGD++ EI+K+G Sbjct: 217 EIIALVSETFTLHPGDIIATGTPEGVGYVRNPPWLLGPGDIVEVEIDKLG 266 >UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomycetales|Rep: Maleylpyruvate isomerase - Rhodococcus sp. (strain RHA1) Length = 275 Score = 144 bits (350), Expect = 2e-33 Identities = 79/202 (39%), Positives = 115/202 (56%), Gaps = 4/202 (1%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+C+GLNY +H QE P P +F+KF + GP V + + ++DWE EL V Sbjct: 69 KIICVGLNYANHIQEMGRDLPEYPTLFAKFKEALTGPYDDVIVPSYAAAQLDWEGELAFV 128 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 VG++A V E DA Q++AGY+V D + RD+Q Q+ GK+ + GP + T+D Sbjct: 129 VGKQAYQVPEADAEQYIAGYSVMNDYTMRDYQYRTL--QWDQGKTFEKTSGFGPFLTTTD 186 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 L L G + QS++T LV + L+ IS ++TL PGD+++TGTPGGVG Sbjct: 187 SYTFGGTL--VTKLEGQVVQSTTTDDLVFTPARLVEYISHIVTLQPGDVVITGTPGGVGH 244 Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279 R+P Y+Q G + IE +G Sbjct: 245 ARKPGLYIQDGQTVEVTIEGLG 266 >UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Herpetosiphon aurantiacus ATCC 23779 Length = 293 Score = 144 bits (349), Expect = 2e-33 Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 9/195 (4%) Query: 60 ATIPLSSVTLTAPI-HGVDKILCIGLNYKDHCQEQ------NLTPPPVPMVFSKFSSTII 112 A I L+ L AP+ + + C+GLNY H +E + P P+ F+K + I Sbjct: 56 AGIQLNMDQLLAPLPRPLKNVFCVGLNYAAHARESLQAKGLEVKMPEHPVFFTKPPTAIN 115 Query: 113 GPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK 172 P + I V++++DWEVEL VV+G+ + E A++HV GYTV D+SARD Q Sbjct: 116 SPTGEIVIDPAVSERIDWEVELGVVIGKAGKNISHEQAMEHVWGYTVINDVSARDLQMRH 175 Query: 173 NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLL 232 QF GK++D CP+GP ++TSDE+ L V +NG +KQ S+T L+ +IP+L+ Sbjct: 176 Q--QFFKGKALDGSCPMGPWIITSDELTDPHNLVVRLRVNGEIKQESNTNDLIFNIPTLI 233 Query: 233 HRISSVMTLVPGDLI 247 H +S MTL PGD+I Sbjct: 234 HVLSQGMTLEPGDII 248 >UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=3; Dehalococcoides|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Dehalococcoides sp. BAV1 Length = 253 Score = 143 bits (347), Expect = 4e-33 Identities = 77/179 (43%), Positives = 113/179 (63%), Gaps = 6/179 (3%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+ IGLNYK H E P +P++F K +S IIGP+ + I+ +++VD+E EL V+ Sbjct: 56 KIIAIGLNYKAHAGEMAEDLPKLPLIFFKNASGIIGPEDNI-IKPGQSERVDYEGELAVI 114 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 + ++ ++ EDA ++ GY+ D++ARD QK GQ+ K DTF GP + T Sbjct: 115 IRKKTRNIKPEDAFDYILGYSCFNDVTARDLQKID--GQWSRAKGFDTFAVCGPWIET-- 170 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVG 256 E+ V+L + LNG LKQ +STA ++ SIP ++ IS VMTL+PGD+I TGTP G+G Sbjct: 171 ELDPQVQL-LETYLNGKLKQRTSTADMIFSIPRIVSFISEVMTLLPGDIIATGTPSGIG 228 >UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isomerase; n=4; Halobacteriaceae|Rep: 2-hydroxyhepta-24-diene-1,7-dioate isomerase - Haloarcula marismortui (Halobacterium marismortui) Length = 257 Score = 143 bits (346), Expect = 5e-33 Identities = 84/204 (41%), Positives = 119/204 (58%), Gaps = 16/204 (7%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 K++CIG NY DH +E + P PM+F K + + + + + + +++D+E EL VV Sbjct: 59 KVVCIGRNYADHAEEMDSELPDRPMLFLKAPNAVASHGKHLTMPSG-KERIDYEAELGVV 117 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +G + V E A+ VAGYT DIS RD Q+ + ++ GK+ D CP+GP V T + Sbjct: 118 IGEQCRNVSESGAMDVVAGYTCVNDISNRDDQRREQ--NWVRGKAFDNACPIGPLVATPE 175 Query: 198 EV--GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 V A++ELR LNG KQSSS L+ S+P L+ I+S MTL PGD+I TGTP GV Sbjct: 176 HVPEDASIELR----LNGETKQSSSREHLIFSVPELIAEITSYMTLEPGDVIATGTPEGV 231 Query: 256 GMYRQPPEYLQPGDVLTSEIEKIG 279 G ++ GD + EIE IG Sbjct: 232 GP-------MEDGDEVEVEIEGIG 248 >UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydrolase; n=1; Burkholderia xenovorans LB400|Rep: Putative fumarylacetoacetate (FAA) hydrolase - Burkholderia xenovorans (strain LB400) Length = 257 Score = 142 bits (345), Expect = 7e-33 Identities = 82/217 (37%), Positives = 118/217 (54%), Gaps = 13/217 (5%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123 L+ L P+ ++ +G+NY H E P +P F ++ IGP + + +R Sbjct: 42 LADAQLLCPLPA-PRLFAVGMNYVGHIAEAGAKTPVIPQFFMMPTTAAIGPGEAI-VRPR 99 Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKS 182 + V E EL +V+GR + E AL HV GYT A D+S R Q +E G L+GK+ Sbjct: 100 EAQVVHHEAELAIVIGRRGRRIDVERALDHVFGYTCANDVSERVIQNREMGYGCLLVGKA 159 Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242 DTFCPLGP + T + G LRV S+NG +Q +T+ L+ ++P ++ +S +TL+ Sbjct: 160 FDTFCPLGPVIATGLDAG---NLRVRASVNGSPRQDGNTSDLLFTVPHIVSYLSQAVTLL 216 Query: 243 PGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 PGD+ILTGTP GVG L GDV I+ IG Sbjct: 217 PGDVILTGTPSGVGP-------LLSGDVCEITIDGIG 246 >UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Syntrophobacter fumaroxidans MPOB|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 235 Score = 142 bits (345), Expect = 7e-33 Identities = 83/216 (38%), Positives = 118/216 (54%), Gaps = 22/216 (10%) Query: 78 KILCIGLNYKDHCQEQNLTP--------PPVPMVFSKFSSTIIGPDQPVRIRTDVTK--- 126 KI+ +GLNY+ H E P P++F K + +IGP + + I + + Sbjct: 19 KIIALGLNYRAHIAESTTVKVRGFTDEVPEEPILFPKTPNVLIGPGESIVIPAFLKEYGF 78 Query: 127 ---KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183 + D+E EL V++ E V DAL+HV GYT D+S R+ Q G F GKS+ Sbjct: 79 PEPRTDYEAELAVIIKDECKNVGPGDALKHVFGYTCMNDVSQRNLQTGDRAGWFR-GKSL 137 Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243 DTF P+GP ++ D++G LR+ C LNGV Q S+T ++ IP ++ +S L+P Sbjct: 138 DTFGPIGPVIVRPDDLGDPHNLRICCRLNGVTVQDSNTGSMIFKIPEIIAFVSRNFKLMP 197 Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 GD+I+TGTP GVG R GDV+ EIEKIG Sbjct: 198 GDVIVTGTPSGVGPIRH-------GDVVEVEIEKIG 226 >UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Nocardioides sp. JS614|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Nocardioides sp. (strain BAA-499 / JS614) Length = 269 Score = 142 bits (344), Expect = 9e-33 Identities = 82/194 (42%), Positives = 110/194 (56%), Gaps = 4/194 (2%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123 L V L AP+ K++ IG NY H E P P++F K ++++IGP P+ Sbjct: 54 LEDVRLLAPVLPRSKVVGIGRNYAAHAAELGNDLPTEPLMFLKPNTSVIGPGDPI-FYPP 112 Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183 T+ + +E EL VV+GR V E A + GYT+ D++ARD Q+ QF K Sbjct: 113 QTQNLHYEGELAVVIGRICRDVPPEQATDVIHGYTIGNDVTARDLQRSDV--QFTRAKGF 170 Query: 184 DTFCPLGPCVLTSDEVGAAVELR-VSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242 D+FCPLGP + T + E R V LNG L Q ST L+ IP+L+ +SSVMTL+ Sbjct: 171 DSFCPLGPWIETDLDPHDFAEGRSVQTHLNGDLVQDGSTKDLIFDIPTLIAYVSSVMTLL 230 Query: 243 PGDLILTGTPGGVG 256 PGD+ILTGTP GVG Sbjct: 231 PGDVILTGTPEGVG 244 >UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Actinomycetales|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 279 Score = 140 bits (340), Expect = 3e-32 Identities = 78/213 (36%), Positives = 113/213 (53%), Gaps = 4/213 (1%) Query: 69 LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128 L A + KI+C+GLNY +H +E P P +F KF +IGP V + K + Sbjct: 60 LDAVVPAPKKIVCVGLNYANHIKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKAL 119 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ--KEKNMGQFLLGKSMDTF 186 DWE E+ V++G+ A V++ DA +++AGY V D + RD+Q Q+ GKS++ Sbjct: 120 DWEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQYAAPAKTPQWHQGKSLEKS 179 Query: 187 CPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDL 246 GP + T D EL + L G QS+ T LV S L+ I+ + L GD+ Sbjct: 180 AGFGPWMTTPDSFEFGGEL--ATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDV 237 Query: 247 ILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 I+TGTPGGVG R P Y+ G+ + EI +G Sbjct: 238 IVTGTPGGVGHARNPQRYIGDGETVKVEIAGLG 270 >UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative FAA hydrolase family protein - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 282 Score = 140 bits (340), Expect = 3e-32 Identities = 78/199 (39%), Positives = 116/199 (58%), Gaps = 17/199 (8%) Query: 69 LTAPIHGVDKILCIGLNYKDHCQEQNLTP-----------PPVPMVFSKFSSTIIGPDQP 117 +T P H V C+G NY H E + P P++F+K SS++ P Sbjct: 80 ITNPPHNV---FCVGKNYHAHAHEFTKSGFDAGATAAEAIPEHPIIFTKPSSSLARPFGD 136 Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF 177 + + + + VD+E EL VV+G+ + E AL HV GYTV D++ARD QK+ Q+ Sbjct: 137 IPLWPGLDEAVDYEAELAVVIGKAGRFITAERALDHVFGYTVFNDVTARDLQKKHK--QW 194 Query: 178 LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237 LGK +D F P+GP ++T DE+ A + ++C++NG +Q +ST L+ IP+L+ IS Sbjct: 195 FLGKGIDGFGPIGPWIVTKDELDIA-NVEITCTVNGEERQKTSTKDLIFDIPTLIEVISR 253 Query: 238 VMTLVPGDLILTGTPGGVG 256 +TL+PGD+I TGTP GVG Sbjct: 254 SVTLLPGDIIATGTPAGVG 272 >UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related protein; n=3; Archaea|Rep: 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related protein - Thermoplasma acidophilum Length = 250 Score = 140 bits (338), Expect = 5e-32 Identities = 73/212 (34%), Positives = 123/212 (58%), Gaps = 7/212 (3%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI +N++ H QE + PP P F+KFS+ ++G + ++ +K+D+E E+ +V Sbjct: 38 KIFLPAVNFRSHSQESDTKFPPKPYFFTKFSNALVGHNGTAHRPREI-EKLDYEGEIGIV 96 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQ--KEKNMG-QFLLGKSMDTFCPLGPCVL 194 +G+ + E+A ++ G+T+ D+SARD+Q + G ++ GK+ D P+GP ++ Sbjct: 97 IGKRGKRIGVEEAQNYIFGFTIVDDVSARDYQFPEMHPYGYNWVQGKAFDEALPVGPYIV 156 Query: 195 TSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGG 254 T DE+ L++ +NG L+QS +T +V S+ L+ +S +TL PGDLI TGTP G Sbjct: 157 TRDEI--RFPLKIETRVNGELRQSGTTEDMVFSVEQLISTVSQTITLEPGDLITTGTPAG 214 Query: 255 VGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286 V + + +YL GD ++ + IG RIE Sbjct: 215 VAAFTE-AKYLSDGDTVSISVSGIGELVHRIE 245 >UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6; Pezizomycotina|Rep: Contig An05c0060, complete genome - Aspergillus niger Length = 290 Score = 139 bits (336), Expect = 9e-32 Identities = 79/215 (36%), Positives = 116/215 (53%), Gaps = 11/215 (5%) Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKK---VDWEVELC 135 I C+GLNY DH +E NL P VP++F+K S +IGP P I + D+E ELC Sbjct: 76 IRCLGLNYIDHAKEANLALPEVPILFTKPRSALIGP-YPASISVPKCAQDGTSDYESELC 134 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLG----- 190 VV+GR + EE+AL +V GYT + D+SAR Q Q+ K +D CP+G Sbjct: 135 VVIGRTGRDIPEENALDYVLGYTASNDVSARTLQMAT--AQWSFSKGLDESCPIGIDRTG 192 Query: 191 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 250 P +++ + LR+ NGV+ Q T ++ SI + +S TL G + LTG Sbjct: 193 PVLVSPSVIKDPQTLRIQGIHNGVVVQDGHTKDMIFSIKRQISYLSQGTTLEAGTIFLTG 252 Query: 251 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 TP G+G ++ P + L+ GD + I+KIG ++ Sbjct: 253 TPAGIGYFKSPRDVLKDGDEFSVYIDKIGTLTNKV 287 >UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family protein; n=8; Desulfuromonadales|Rep: Fumarylacetoacetate hydrolase family protein - Geobacter sulfurreducens Length = 218 Score = 138 bits (335), Expect = 1e-31 Identities = 79/213 (37%), Positives = 122/213 (57%), Gaps = 11/213 (5%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 + KILCIG NY +H +E P P+VF K ++ +IG + + I + +++ E EL Sbjct: 15 IGKILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIPS-YSRECHHEAELA 73 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLGPCV 193 +++G+ + E AL+HVAGY VA D++ RD Q E K G + + K DT CPL V Sbjct: 74 LLIGKGGKDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSFV 133 Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253 +D V +L ++ +NG ++Q S++ ++H IP +L +S V TL PGD+ILTGTP Sbjct: 134 -PADRVADPHDLHITLRVNGEMRQDGSSSLMIHRIPQILSYMSGVFTLEPGDVILTGTPA 192 Query: 254 GVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286 GVG L GD + +E+ + A V ++ Sbjct: 193 GVGP-------LAAGDAVEAEVVGVAAIRVTVK 218 >UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase; n=1; Methanopyrus kandleri|Rep: 2-keto-4-pentenoate hydratase hydratase - Methanopyrus kandleri Length = 264 Score = 138 bits (335), Expect = 1e-31 Identities = 85/221 (38%), Positives = 126/221 (57%), Gaps = 18/221 (8%) Query: 63 PLSSVTLTAPIHGVDKILCIGLNYKDHCQE---QNLTPPPVPMVFSKFSSTIIGPDQPVR 119 PLS + + P+ KI+C GLNY++H +E + P P++ K + +IG V+ Sbjct: 50 PLSELRIGPPVPRPPKIICFGLNYREHVEELREMGMDVPSEPVMTMKAPTAVIGHLDTVK 109 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLL 179 + + ++VD E+EL VV+G V E+A V G+T+ D++ARD +K + GQ++ Sbjct: 110 LPREA-RRVDHELELAVVIGERCRKVSPEEARDAVLGFTIINDVTARDIEKRE--GQWVR 166 Query: 180 GKSMDTFCPLGPCVLTSDEV-GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238 KS DTF PLGP + T E G +ELRV NG ++Q ++T +V L+ S V Sbjct: 167 AKSYDTFAPLGPWIETELEPDGLEMELRV----NGEVRQRATTDDMVRDPYELVSFTSRV 222 Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 MTL PGD+I TGTP GVG ++P D + EIE+IG Sbjct: 223 MTLEPGDIIATGTPPGVGP-------MEPDDKIELEIERIG 256 >UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_03001459; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03001459 - Ferroplasma acidarmanus fer1 Length = 274 Score = 138 bits (334), Expect = 2e-31 Identities = 90/258 (34%), Positives = 131/258 (50%), Gaps = 13/258 (5%) Query: 32 DSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQ 91 D + T + L + D K+K + + T +S+ I +LCIGLNYK H Sbjct: 27 DYGIKATSVAELSHDDFAKLKDINRFQDYTFSYNSI-----IDQKSSLLCIGLNYKSHVS 81 Query: 92 EQ-NLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDA 150 E P P+VFSK ++ G V+ T +D+E ELCV++G+ A V E +A Sbjct: 82 EHAGGKIPETPVVFSKANNAFTGNHSIVQ--TGNGMHMDYEGELCVMIGKTARNVGEANA 139 Query: 151 LQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCS 210 L +V GY + D+S+R Q + QF LGKS D F P GP + + E+ L + Sbjct: 140 LNYVLGYFIGNDVSSRLMQYKTT--QFFLGKSFDNFYPNGPYI-SIGEINDPQNLTIQTR 196 Query: 211 LNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV--GMYRQPPEYLQPG 268 +NG L+Q S+T ++ + L+ IS MTL PGD I TGTP GV GM ++L G Sbjct: 197 VNGELRQDSNTGLMIFPVNKLISYISQFMTLRPGDCISTGTPAGVIMGMPESNQKWLGKG 256 Query: 269 DVLTSEIEKIGAFDVRIE 286 D + +I +G + E Sbjct: 257 DKVEVQITGLGKLETTFE 274 >UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Bacillus halodurans|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus halodurans Length = 276 Score = 138 bits (334), Expect = 2e-31 Identities = 90/273 (32%), Positives = 148/273 (54%), Gaps = 16/273 (5%) Query: 14 NIRVGYLEGDDIVDIN----KADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTL 69 + ++G ++ + I DI+ P TLL I D + + + + + L+ V L Sbjct: 8 DFQLGLVKEEMIYDISLLLPNPTGGCPMTLL-IEHFDDYKTTIEQEYHRQPSYRLNDVRL 66 Query: 70 TAPIHGVDKILCIGLNYKDHCQEQNLTPPP-VPMVFSKFSSTIIGPDQPVRIRTDVTKKV 128 P+ KI+ +NY H +E N+ V F K +++IIGP+ P+ + + +++ Sbjct: 67 RQPLSRPGKIVAAPVNYMSHKKEMNVDHTARVLGFFLKATTSIIGPNDPIILPYN-NRRI 125 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCP 188 D E+EL V+G+ A V++E+A ++ GYT D++ R + + + L KS DTF P Sbjct: 126 DHELELAFVIGKRAKHVKKENAHDYIFGYTGLNDVTVRPTKNREE--ERCLRKSFDTFTP 183 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 +GP ++TSDE+ L +S +N ++Q +T Q+V I L+ S VMTL PGDLI Sbjct: 184 IGPWIVTSDEIKDPQNLTISLQVNHEVRQHVNTNQMVCGIAELVEIFSHVMTLEPGDLIA 243 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAF 281 TGTP GVG ++ GD +T ++E IG+F Sbjct: 244 TGTPDGVGP-------IKDGDTVTLQMESIGSF 269 >UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Halorubrum lacusprofundi ATCC 49239 Length = 304 Score = 138 bits (334), Expect = 2e-31 Identities = 85/213 (39%), Positives = 121/213 (56%), Gaps = 20/213 (9%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+CIG NY DH E + P P++F K + + + + ++DWE E+ VV Sbjct: 106 KIVCIGRNYADHAAELDNDVPDRPLLFLKPPNALASHGDEITVPAG-KDRIDWEAEIAVV 164 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFCPLGPCVLTS 196 +G + V +DA+ VAG+T D+S RD Q +E+N ++ GK+ D PLGP + T Sbjct: 165 IGEQCKDVDADDAMDVVAGFTCMNDVSNRDDQDREQN---WVRGKAFDGAAPLGPVMATP 221 Query: 197 DEV--GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGG 254 DEV A+VELRV NG KQSS + L+ +P+L+ I++ +TL PGD+I TGTP G Sbjct: 222 DEVPADASVELRV----NGETKQSSDRSYLMFDVPTLIEEITTYLTLEPGDVISTGTPEG 277 Query: 255 VGMYRQPPEYLQPGDVLTSEIEKIGAF--DVRI 285 VG L GD + EIE +G DVR+ Sbjct: 278 VGA-------LSDGDTVEVEIEGVGTLEHDVRV 303 >UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1; n=1; Debaryomyces hansenii|Rep: Similar to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 289 Score = 138 bits (333), Expect = 2e-31 Identities = 78/217 (35%), Positives = 118/217 (54%), Gaps = 9/217 (4%) Query: 69 LTAPIHGVDK--ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126 L P+ G D + CIG+NYK+H + PPP P +F K +++ ++ + I Sbjct: 67 LLGPLTGEDVPVVKCIGMNYKEHLMGI-IEPPPYPQLFYKPRTSVADQNEDIPIPLFAQN 125 Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ----KEKNMGQFLLGKS 182 D+E ELCVV+G+ + EEDAL +VAGY D+SARDWQ + Q KS Sbjct: 126 TCDYEGELCVVIGKTGKNINEEDALSYVAGYVSGNDLSARDWQYFPEYAGKVPQLGFSKS 185 Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242 D + PLGP +++S + L++ +NG L+Q+ T L+ I ++ IS TL Sbjct: 186 FDRYAPLGPAIVSSKIIKDPHALQLQTRINGDLRQNCGTDDLLFGISRIIAFISQETTLE 245 Query: 243 PGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 G +I+TGTP G G +YL+ GD++ I++IG Sbjct: 246 QGTVIMTGTPNGCGGI--DGKYLKDGDLVEVTIDQIG 280 >UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Leptospirillum sp. Group II UBA|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Leptospirillum sp. Group II UBA Length = 267 Score = 137 bits (332), Expect = 3e-31 Identities = 85/243 (34%), Positives = 137/243 (56%), Gaps = 14/243 (5%) Query: 38 TLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP 97 TL + + D ++ L + L V L P+ KI+ +GLNY+ H E Sbjct: 21 TLFWGVLSEDGSRLHPLSGPGHGSFSLLDVRLHPPVTP-GKIIAVGLNYRAHGNEMGKPL 79 Query: 98 PPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGY 157 P P++F K +S ++ P+ +R+ ++++VD+E E+ +V+G++AS + E+ V G Sbjct: 80 PEEPLLFMKATSALLPPNGEIRLPR-MSRRVDFEGEIALVMGKKASGISPEEVPLFVYGI 138 Query: 158 TVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQ 217 T A D++ARD QK K++ Q+ KS DTFCPLGP +LT + R+ +NGV++Q Sbjct: 139 TCANDVTARDLQK-KDV-QYTRAKSFDTFCPLGPVILTG---ALPDDRRLRTEVNGVVRQ 193 Query: 218 SSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEK 277 + + ++ +L+ IS VMTL PGD+ILTGTP GVG L P D ++ +E Sbjct: 194 EARASDMIFDPLTLVSFISQVMTLEPGDVILTGTPSGVGP-------LSPMDRVSVSLEG 246 Query: 278 IGA 280 +G+ Sbjct: 247 VGS 249 >UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=2; Microbacteriaceae|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Leifsonia xyli subsp. xyli Length = 291 Score = 137 bits (331), Expect = 3e-31 Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 8/270 (2%) Query: 16 RVGYLEGDDIVDINKADSSLPTTLLQILRNGD--LEKVKKL-KSTKPATIPLSSVTLTAP 72 R+ + GD + +++ + P L +++ G+ L V+ L A PL+ V Sbjct: 15 RLAAVIGDGALFLDEMMAQAPRDLQELIERGEEALTDVRALVNEAVTAKTPLTLVQELRH 74 Query: 73 IHGV---DKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVD 129 V +++ IG NY H E L VFS + +++ G D+ +VD Sbjct: 75 ASAVLRPPQVIAIGANYAAHASELKLRSEKAATVFSLWPNSLAGHGGTTSWPGDLATQVD 134 Query: 130 WEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPL 189 +E EL V++G+ A V +DAL +V GYTV DI+ARD Q + Q+ KS D F P Sbjct: 135 YEAELGVIIGKPARDVLAQDALDYVWGYTVVNDITARDLQFSE--AQWSRCKSFDGFTPN 192 Query: 190 GPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILT 249 GP +T+DEV +L ++ +++G + Q +STA +V S+ ++ +S T+ G LI T Sbjct: 193 GPVAVTADEVPDPQDLWLTTNVDGAILQDASTADMVRSVAEIIEFLSRSATIPAGTLIST 252 Query: 250 GTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 G+PGG G R PP +L +T I IG Sbjct: 253 GSPGGAGYSRTPPVFLHDRSTVTVSIGGIG 282 >UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Fumarylacetoacetate hydrolase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 291 Score = 137 bits (331), Expect = 3e-31 Identities = 95/286 (33%), Positives = 153/286 (53%), Gaps = 18/286 (6%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 60 MKL F+ D VG GD I D+ D+ L+++ R E +++ + PA Sbjct: 1 MKLTTFAAADG--RTVVGIHRGDTI-DVVGVDNM--RELIKLTRGNPAEIERRVTGSVPA 55 Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL---TPPPVP-MVFSKFSSTIIGPDQ 116 + L API I G N+K+H E + P +VF + I+GP+ Sbjct: 56 ----AGGRLLAPIKPTKLIHTAG-NFKEHEDESKRVGWSHNVGPWIVFMQNVDAIVGPED 110 Query: 117 PVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-EKNMG 175 +R +TK++D+E+EL VV+ ++ EDA+ +VAGY + D++ARD Q+ E G Sbjct: 111 GIRYPDHLTKELDYELELSVVINQDVGEFAPEDAMNYVAGYVIFNDVTARDIQRDEMKSG 170 Query: 176 QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235 F K +D+FCP+GP ++T+DE+ +L++ +NG +Q S ++++ +IP +L R Sbjct: 171 VFGFCKGIDSFCPIGPWIVTADEIPNPHDLKMELRVNGEPRQESHSSRMWTTIPEILARY 230 Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPE--YLQPGDVLTSEIEKIG 279 S + GD++ TGT GV +R E YL+ GD + E+EKIG Sbjct: 231 SP-LGYSAGDIVTTGTVSGVAGFRVDAEDYYLRVGDSVECEVEKIG 275 >UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomycotina|Rep: RIB40 genomic DNA, SC005 - Aspergillus oryzae Length = 299 Score = 137 bits (331), Expect = 3e-31 Identities = 72/206 (34%), Positives = 116/206 (56%), Gaps = 7/206 (3%) Query: 81 CIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI-RTDVTKKVDWEVELCVVVG 139 C+GLNY H +E PPP P +F K ++ + +PV I R + D+E ELC+++G Sbjct: 85 CVGLNYAKHIKEAGRKPPPFPFIFFKPNTCVHDHGKPVVIPRIAQNDQADYEGELCLIIG 144 Query: 140 REASCVREEDALQHVAGYTVAQDISARDWQKEKNMG----QFLLGKSMDTFCPLGPCVLT 195 ++A V E AL++VA YT DIS+R Q++ Q+ K DTF PLGP ++ Sbjct: 145 KDAKDVSPEHALEYVAAYTAGNDISSRKLQRDPAYAGVVPQWGFSKGFDTFAPLGPVLVA 204 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 + E+ +L + ++G ++Q + L+ L+ +S TL G +I+TGTPGG+ Sbjct: 205 ASEIPDPSQLHLKTIVDGEVRQDETVGDLLFDCKYLISYLSQGTTLQKGSVIMTGTPGGL 264 Query: 256 GMYR--QPPEYLQPGDVLTSEIEKIG 279 G+ +PP++L PG + +I +IG Sbjct: 265 GVGAGFKPPKWLVPGTQMDVQISQIG 290 >UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - Pseudomonas abietaniphila Length = 289 Score = 136 bits (328), Expect = 8e-31 Identities = 83/222 (37%), Positives = 122/222 (54%), Gaps = 9/222 (4%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 + LS VTL PI V++++ G NY H E L+ P P+ F K +IG P+R Sbjct: 55 LALSQVTLLPPIEPVNRVVVAGANYAKHLVEFGLSAPSQPVAFLKAYGALIGAHDPIRF- 113 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE--KNMGQFLL 179 +T ++D EVEL V+G + V +D L V GYTV D+SARD Q+ K +G L Sbjct: 114 PPLTTELDHEVELVAVIGSDD--VDLDDPLACVLGYTVGNDVSARDLQRSGPKGIGMDLF 171 Query: 180 -GKSMDTFCPLGPCVLTSDEV-GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237 KS D LGP V+T DE+ + +LR++ +NG ++Q +TA + + L+ + Sbjct: 172 AAKSQDKTTGLGPWVVTKDELPEGSPKLRLTLKVNGQMRQDGNTADMTWDVGELIAFVQQ 231 Query: 238 VMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + GD++ TG+P GVGM +L PGDV+ + IE IG Sbjct: 232 RSSFACGDVLFTGSPAGVGM--GTGIFLDPGDVVEASIEGIG 271 >UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family protein; n=2; Cystobacterineae|Rep: Fumarylacetoacetate hydrolase family protein - Stigmatella aurantiaca DW4/3-1 Length = 257 Score = 136 bits (328), Expect = 8e-31 Identities = 81/223 (36%), Positives = 123/223 (55%), Gaps = 14/223 (6%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123 LSS+TL P K++CIG NY+ H +E P P++F K S+ + GP P+R+ Sbjct: 46 LSSLTLLVPSEA-SKVVCIGQNYRKHAEEMGKPVPSEPLLFIKPSTALNGPRSPIRL-PK 103 Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183 +++V +E EL +V+G E A + + G T D++ARD Q+ + Q KS Sbjct: 104 ASQEVHYEAELGLVIGERLKNADEATAARAIWGLTCINDVTARDIQRREV--QHTRAKSY 161 Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243 DTF +GP +T + +LR+ C +NG ++Q S T+ +V + L+ IS +MTL+P Sbjct: 162 DTFACVGPWAVTGL---SPADLRILCRVNGQVRQDSRTSDMVFNPAQLVSFISHIMTLLP 218 Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286 GDL+ TGTP GVG L GD++ E+E IG +E Sbjct: 219 GDLVSTGTPSGVGA-------LAAGDMVEVELEGIGTLANPVE 254 >UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Lawsonia intracellularis PHE/MN1-00|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Lawsonia intracellularis (strain PHE/MN1-00) Length = 257 Score = 135 bits (327), Expect = 1e-30 Identities = 82/227 (36%), Positives = 128/227 (56%), Gaps = 13/227 (5%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 IPLS + + P+ KI+CI +NY + QE P P F K S+I+G QP+ + Sbjct: 36 IPLSKIKVL-PLVSPTKIICIDINYHEKAQELQQPIPTNPTFFFKPPSSIVGNGQPILLP 94 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 T++ + V E ELC+V+G+ V E A ++ GYT A DI+A+D Q+++ K Sbjct: 95 TNIGRVVS-EAELCIVIGQTCYKVTPEAASNYIFGYTCANDITAKDIQQQEYTTSH--AK 151 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 + +TFCP+GP + T +V L++ S+N L Q S+TA ++ L+ +S++MTL Sbjct: 152 AYNTFCPVGPWIET--DVPNIENLQIRNSINSELGQVSTTADMIFPPLELISFLSNIMTL 209 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288 PGDLILTGTP G + + GD++ + IE +G IE++ Sbjct: 210 NPGDLILTGTPKGSLL-------ISDGDIVQTSIENVGILINPIEEY 249 >UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase; n=4; Deinococci|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase - Deinococcus radiodurans Length = 262 Score = 134 bits (325), Expect = 2e-30 Identities = 76/205 (37%), Positives = 116/205 (56%), Gaps = 9/205 (4%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 K++ + LNY DH E P P++F K +++++ P Q I K + +EVEL +V Sbjct: 46 KVIALALNYADHVAELGFKAPEEPVMFLKPNTSLL-PHQGTVIYPRGAKFMHYEVELGIV 104 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +GR+A V+ +DA +V GYT+A D+ RD+ + K DTF PLGP ++++D Sbjct: 105 IGRDARRVKAKDADDYVGGYTIANDLVVRDYVSNYYRPP-MRAKGWDTFGPLGPYLVSAD 163 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 EV L + +NG L+Q ST ++ P L+ +S MTL GD+ILTGTP GV Sbjct: 164 EVPDPYNLGLRAYVNGELRQEGSTRDMILKAPELIEFMSRFMTLEAGDVILTGTPKGV-- 221 Query: 258 YRQPPEYLQPGDVLTSEIEKIGAFD 282 ++ PGDV+ EI+ +GA + Sbjct: 222 -----SHVHPGDVMRLEIDGLGALE 241 >UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albicans IPF5534; n=2; Ascomycota|Rep: Similar to CA3735|IPF5534 Candida albicans IPF5534 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 208 Score = 134 bits (324), Expect = 2e-30 Identities = 73/207 (35%), Positives = 116/207 (56%), Gaps = 7/207 (3%) Query: 84 LNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI-RTDVTKKVDWEVELCVVVGREA 142 +NY H QE +L PPP P +F K +++ ++ + I + + D+E E CVV+ + Sbjct: 1 MNYMKHIQEGSLPPPPKPQIFYKPRTSVGDHNEAIAIPKIAQENQCDYEGEFCVVIVKTG 60 Query: 143 SCVREEDALQHVAGYTVAQDISARDWQKEK----NMGQFLLGKSMDTFCPLGPCVLTSDE 198 ++EEDAL +VAGY V D+SAR WQ N+ Q+ KS D + PLGP + ++ Sbjct: 61 KHIKEEDALNYVAGYIVGDDVSARIWQYHPDYSGNIPQWYYSKSFDRYAPLGPALFSTRV 120 Query: 199 VGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMY 258 + L++ +NG L+Q ++T L+ +I ++ +S TL G +I+TGTP GVG Sbjct: 121 IKNPHTLQLQTRINGELRQDANTDDLLFNIQKIIAFLSQGTTLEQGTVIMTGTPSGVGAV 180 Query: 259 RQPPEYLQPGDVLTSEIEKIGAFDVRI 285 YL+ GD++ IE+IG +I Sbjct: 181 --SGRYLKDGDLVEISIEQIGTLSHKI 205 >UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; Dikarya|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 311 Score = 134 bits (324), Expect = 2e-30 Identities = 73/197 (37%), Positives = 112/197 (56%), Gaps = 5/197 (2%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGP-DQPVRIRTD--VTKKVDWEV 132 V I CIGLNY +H +E NL P +P +F K S+++ P P I + D+E Sbjct: 96 VGTIRCIGLNYVNHAKEVNLPMPDIPTLFMKPSTSLADPFPSPTIIPKAFVASNSADFES 155 Query: 133 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPC 192 E+ V+G++A V EE+AL +V G+T A D+S+R+ Q ++ Q+ KS D CP+GP Sbjct: 156 EVAFVIGKDAKNVSEEEALDYVLGFTAANDVSSREAQFAQS--QWCYSKSFDGACPIGPA 213 Query: 193 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252 ++ ++ ++++ SLNG QSS L+ S+P ++ +S TL G +I+TGTP Sbjct: 214 LVNKNQANKFSDVKIEGSLNGKTVQSSRLDDLIFSVPKIVSFLSQGTTLPAGTIIITGTP 273 Query: 253 GGVGMYRQPPEYLQPGD 269 GVG P L+ GD Sbjct: 274 AGVGWSSTPRITLKDGD 290 >UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Mesorhizobium sp. BNC1|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 307 Score = 133 bits (322), Expect = 4e-30 Identities = 100/307 (32%), Positives = 152/307 (49%), Gaps = 38/307 (12%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGD---DIVDIN--KADSSLPTTLLQILRNGDLEKVKKLK 55 +KLV +S P+ IR ++ D D D+ A +S+P L ++ Sbjct: 4 LKLVSYS---GPRGIRTAAVKADRYVDAADVTGVAAHASMPGLLADWAAAE--RPLQAAF 58 Query: 56 STKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE----------------QNLTPPP 99 + A + L + P+ G I CIG NY DH E Q Sbjct: 59 AAGQAMVGLPKLVAPLPLPGA--IYCIGANYADHIAEMQGGGTNGASVAAERKQQKEDGL 116 Query: 100 VPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTV 159 P F K S ++ GP+ V + +KKVDWE EL VV+GR++ + E+AL V GYT+ Sbjct: 117 KPWFFIKSSHSVCGPETKVALPA-TSKKVDWEAELAVVIGRKSRDLTIENALTAVWGYTI 175 Query: 160 AQDISARDWQKEKNMGQ-------FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLN 212 A D+SARD + + Q + KS D CP+GP ++++ ++ A +L + S+N Sbjct: 176 ANDLSARDLSRRPPLPQGSPFFFDWTSHKSFDDSCPMGPWIVSASQIVDANDLDIGLSIN 235 Query: 213 GVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLT 272 G Q S+T+Q++ ++ + +S +TL PGD+ILTGTP GVG R L+P D ++ Sbjct: 236 GQPMQKSNTSQMIFTVAEQVAHLSQRITLWPGDIILTGTPAGVGAGRNLS--LKPSDEVS 293 Query: 273 SEIEKIG 279 IE IG Sbjct: 294 VYIEGIG 300 >UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=3; Bacillaceae|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Geobacillus kaustophilus Length = 262 Score = 133 bits (321), Expect = 6e-30 Identities = 84/214 (39%), Positives = 125/214 (58%), Gaps = 16/214 (7%) Query: 67 VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126 V+L AP+ ++ IG NY ++ + P +P+ F K SS+++GP+ V I + V + Sbjct: 45 VSLVAPL-APRHVIGIGANYVASSEQLPVELPDIPVFFFKPSSSVVGPEAEVVIPSGVGE 103 Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTF 186 V +E EL VV+G+EA V EED ++ GYTVA D++A + G + +GKS DTF Sbjct: 104 -VKFESELAVVIGKEAKQVSEEDVWSYIFGYTVANDVTAPQFFHPD--GHWTIGKSFDTF 160 Query: 187 CPLGPCVLTS-DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245 PLGP + T D +V+ RV NG KQ+SST ++ SI ++ +S VMTL PGD Sbjct: 161 TPLGPVIETELDPRAVSVKARV----NGEEKQNSSTKLMIISISKMISYLSHVMTLQPGD 216 Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +ILTG+P G E + PG V+ +++ IG Sbjct: 217 VILTGSPVGA-------ELVGPGTVIECDVDGIG 243 >UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Jannaschia sp. CCS1|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Jannaschia sp. (strain CCS1) Length = 271 Score = 132 bits (320), Expect = 8e-30 Identities = 78/217 (35%), Positives = 116/217 (53%), Gaps = 12/217 (5%) Query: 67 VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTK 126 VT P+ KILC+ LNY DH +E N P P+VF K +I P+R +T+ Sbjct: 48 VTALPPVTPTAKILCVALNYVDHAKEANQPVPETPIVFFKTFDAMIAGGAPIRAPRMITQ 107 Query: 127 KVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMG----QFLLGKS 182 +D+E EL +++G+ + + DA H+AG T D+SARD K K + GK Sbjct: 108 -LDYEGELALIIGKRGFDIAKTDAWDHIAGVTTLNDVSARDIFKVKAGAASHLDWFSGKC 166 Query: 183 MDTFCPLGPCVLT----SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238 ++ P+GP V D++ A R+ C +NG ++Q + A ++ IP+++ ISS Sbjct: 167 LNQSTPIGPEVFPLSAIEDDLKAGTT-RIRCLVNGEVRQDAPVADMIFDIPTMIAFISSR 225 Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275 + L PGD+I TGTP GVG YL GDV+ E+ Sbjct: 226 IPLNPGDIIATGTPPGVG--AGTDRYLSKGDVVRVEV 260 >UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family protein; n=13; Campylobacter|Rep: Fumarylacetoacetate hydrolase family protein - Campylobacter jejuni subsp. jejuni CF93-6 Length = 292 Score = 132 bits (320), Expect = 8e-30 Identities = 89/288 (30%), Positives = 140/288 (48%), Gaps = 16/288 (5%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTT-LLQILRNGD--LEKVKKLKST 57 MK V F + + +G V +N AD + + +++ N D K K L S Sbjct: 1 MKFVNFKFN---QKATLGVFNSSGKV-VNLADLDINVRDMNELIINFDEFKHKFKDLDSK 56 Query: 58 KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE------QNLTPPPVPMVFSKFSSTI 111 IP L I I+C+G+N+ DH +E + P+ F K + Sbjct: 57 TAYEIPKEDY-LAPIIEPRQDIICLGINFLDHAKESAQFKGEKFEEREYPVYFGKRCNQA 115 Query: 112 IGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE 171 P + + DVT ++D+E EL ++ ++A ++ EDA ++ GYT+ +ISARD QK Sbjct: 116 TAPFGSISLHADVTSQLDYECELAFILSKDAYKIKAEDAKDYIFGYTIINEISARDLQKR 175 Query: 172 KNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSL 231 QF KS++ +GP + + DE+ EL + +N L+Q+S+T + I + Sbjct: 176 HK--QFYRAKSLEGSTIMGPYITSVDEIAYPPELHLKSYVNKELRQNSNTKFFIFDIGYV 233 Query: 232 LHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 L +SS M L G +I GTP GVGM PP +L+ GD + IE +G Sbjct: 234 LEELSSGMLLKAGTIISMGTPSGVGMGLNPPVFLKKGDEVRCVIENLG 281 >UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Corynebacterium jeikeium K411|Rep: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Corynebacterium jeikeium (strain K411) Length = 272 Score = 132 bits (319), Expect = 1e-29 Identities = 83/238 (34%), Positives = 124/238 (52%), Gaps = 16/238 (6%) Query: 52 KKLKSTKPATIPLSSVT---LTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFS 108 +++ ST+ ++P S T L + KI C+GLNY++H E P P +F K++ Sbjct: 45 EQVTSTELDSLPTVSFTADQLGPVVPNPGKIFCVGLNYREHIAEMGHPIPDHPTLFVKYA 104 Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168 S + GP V + +++ + D+E EL V++G +AGYTV D S RDW Sbjct: 105 SALAGPFDEVVVPPELSAQADYEGELAVIMGE----------FGQIAGYTVMNDFSQRDW 154 Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCS-LNGVLKQSSSTAQLVHS 227 Q Q+L GK++D GP ++ ++ E V + +NG L+Q S A LV Sbjct: 155 QYRTQ--QWLQGKNLDRSSGFGPWMVPTEHFDPIAEGAVLRTWVNGELRQEHSVADLVFK 212 Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 L+ IS+ +L PGD+I+TGTP GVG PP+YL GD + I+ IG RI Sbjct: 213 PQDLVDYISNFASLAPGDVIVTGTPEGVGHGMTPPQYLADGDEVRIAIDGIGEICNRI 270 >UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Polynucleobacter sp. QLW-P1DMWA-1 Length = 309 Score = 132 bits (319), Expect = 1e-29 Identities = 84/266 (31%), Positives = 138/266 (51%), Gaps = 18/266 (6%) Query: 36 PTTLLQILRNGDLEKVKKLKSTKPAT-------IPLSSVTLTAPIHGVDKILCIGLNYKD 88 P+ + LR+GD E + + KS + + +++T PI DK LC+G NY+ Sbjct: 44 PSDMKTFLRSGD-EVMNQAKSWVASNGDHSDLLLDANTITYLPPIMDADKFLCVGKNYRT 102 Query: 89 HCQEQNLTP-----PPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREAS 143 H +E T P P F K +S + G + V +R K+D+E EL V+G+ A Sbjct: 103 HLEELKRTNLIKEIPQEPTSFIKLNSCLSGHNATV-VRPKGITKLDYEPELVFVMGKRAL 161 Query: 144 CVREEDALQHVAGYTVAQDISARDWQ-KEKNMG-QFLLGKSMDTFCPLGPCVLTSDEVGA 201 ++ +A+ ++ G T+ D++ RD Q +E G +F GK++ F PLGP ++T DE+ Sbjct: 162 GAKKSEAMDYIGGVTILNDLTCRDLQLREVASGSRFWTGKNIPGFGPLGPEIITIDEIPN 221 Query: 202 AVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP 261 +L ++CS+NG + +T + I +L S + + GD+ TG PGGV + ++ Sbjct: 222 PYDLWMTCSVNGEERMRVNTQDQIWKISDILEHFSRFIPIEAGDMFSTGAPGGVAVGKEN 281 Query: 262 PE--YLQPGDVLTSEIEKIGAFDVRI 285 E YL+PGDV+ I+ I I Sbjct: 282 AEALYLKPGDVVECAIDGISTLRTTI 307 >UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 293 Score = 132 bits (318), Expect = 1e-29 Identities = 89/277 (32%), Positives = 141/277 (50%), Gaps = 26/277 (9%) Query: 16 RVGYLEGDDIVDINKAD-----SSLPTTLLQILRNGD-LEKVKKLKSTKPATIPLSSVTL 69 R+G + GD IVD+ A S P ++Q++ N + L + + PL+SV L Sbjct: 10 RIGVVSGDRIVDVTPAAGVDPASWPPVGMVQVIANFERLRATFQHQLDAGGGKPLASVRL 69 Query: 70 TAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMV-------FSKFSSTIIGPDQPVRIRT 122 PI +K++ NY H E + F K +S++ GP P+ + Sbjct: 70 ECPIAWPNKVVAFPANYHAHIDEMKAGSGLISNFAAAGQGFFLKANSSLSGPADPIVLPN 129 Query: 123 DVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKS 182 ++V E EL V++G+ + E+ALQHV GY+ D R KE+ + + KS Sbjct: 130 LDGREVHHESELAVIIGKRGRNIPRENALQHVFGYSCLIDAVVRG--KEERV----MRKS 183 Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242 DTFCPLGP ++T++EV + + ++NG ++Q ++T L+ +P ++ SSVMTL Sbjct: 184 YDTFCPLGPWLVTAEEVPDPANIDIELTVNGEVRQKANTRALIVDVPEMIAMASSVMTLE 243 Query: 243 PGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 PGD+I +GTP GVG + PGD + I +G Sbjct: 244 PGDIIASGTPSGVGP-------MLPGDAVCITIAGVG 273 >UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase; n=2; Ostreococcus|Rep: Predicted fumarylacetoacetate hydralase - Ostreococcus tauri Length = 322 Score = 132 bits (318), Expect = 1e-29 Identities = 86/242 (35%), Positives = 128/242 (52%), Gaps = 18/242 (7%) Query: 52 KKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPV--------PMV 103 + L+ + PL L + I C+G NY +H E + T P + P++ Sbjct: 75 RSLRVDASLSTPLEECELLCAVDRDVTIACVGKNYLEHVGEVDSTMPGISRMDVPEAPII 134 Query: 104 FSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCV----REEDALQ-HVAGYT 158 FSK S+++ I T K VD+E EL V+GRE + +ED ++ +V G++ Sbjct: 135 FSKASTSLNA--HLGSIATRGRKDVDYEGELVAVIGRECRDIDPGMSDEDVVKNYVIGWS 192 Query: 159 VAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAV-ELRVSCSLNGVLKQ 217 +A D++AR+ QK Q+ LGKS DT CPLGP V D A+ ++ ++N ++Q Sbjct: 193 IANDVTARELQKTHQ--QWFLGKSGDTHCPLGPWVCCDDGRAPALGAASITTAVNSEIRQ 250 Query: 218 SSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEK 277 S+ QL+ S+ +L+ IS TL GD +LTGTP GVG PP +LQPGD IE Sbjct: 251 RSTVDQLIWSVGALIACISRHQTLRVGDCVLTGTPSGVGAGFDPPRFLQPGDACEVTIEG 310 Query: 278 IG 279 +G Sbjct: 311 VG 312 >UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Methanosphaera stadtmanae (strain DSM 3091) Length = 256 Score = 132 bits (318), Expect = 1e-29 Identities = 77/203 (37%), Positives = 121/203 (59%), Gaps = 16/203 (7%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+C+GLNYKDH +E N+ P P++F K S+++I + + I T +D+E EL +V Sbjct: 64 KIVCVGLNYKDHAKELNMELPDEPLLFMKPSTSVISTNSAI-IYPSTTNMLDFEGELGIV 122 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 + + S ++ +VA YT+ D++ARD Q + GQ+ KS DTFCP GP V+T Sbjct: 123 ILEKVSPC--DNGTCNVA-YTIVNDVTARDLQSKD--GQWTRSKSYDTFCPCGPVVVTGI 177 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 + + L + +N +KQ S+T ++ S L+ IS++MTL PGD+I +GTP GVG Sbjct: 178 D---SSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVG- 233 Query: 258 YRQPPEYLQPGDVLTSEIEKIGA 280 +L GD + EI+++G+ Sbjct: 234 ------HLDVGDTVVVEIDEMGS 250 >UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2- hydroxymuconate Delta-isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5- tricarboxylate decarboxylase) (OPET decarboxylase)]; n=42; Proteobacteria|Rep: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2- hydroxymuconate Delta-isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5- tricarboxylate decarboxylase) (OPET decarboxylase)] - Escherichia coli Length = 429 Score = 132 bits (318), Expect = 1e-29 Identities = 85/250 (34%), Positives = 127/250 (50%), Gaps = 12/250 (4%) Query: 36 PTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL 95 P +++L G + + T S TL P HG + +GLNY DH E Sbjct: 185 PGDRVRVLAEGFPPLENPVVDEREVTTRKSFPTLPHP-HGT--LFALGLNYADHASELEF 241 Query: 96 TPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVA 155 PP P+VF K +T+ G +Q +R + + + +E EL VV+G++A V E DA+ +VA Sbjct: 242 KPPEEPLVFLKAPNTLTGDNQ-TSVRPNNIEYMHYEAELVVVIGKQARNVSEADAMDYVA 300 Query: 156 GYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVL 215 GYTV D + RD+ E L KS D P+ ++ + + L + +NG L Sbjct: 301 GYTVCNDYAIRDYL-ENYYRPNLRVKSRDGLTPMLSTIVPKEAIPDPHNLTLRTFVNGEL 359 Query: 216 KQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275 +Q +TA L+ S+P L+ +S MTL PGD+I TGTP G+ + PGD + E+ Sbjct: 360 RQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPKGL-------SDVVPGDEVVVEV 412 Query: 276 EKIGAFDVRI 285 E +G RI Sbjct: 413 EGVGRLVNRI 422 Score = 80.2 bits (189), Expect = 6e-14 Identities = 58/173 (33%), Positives = 84/173 (48%), Gaps = 16/173 (9%) Query: 97 PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAG 156 PP + F K +T+IG +P+ +KV + ++VG+ A+ VREEDA +++AG Sbjct: 31 PPKTAVWFIKPRNTVIGCGEPIPFPQG--EKVLSGATVALIVGKTATKVREEDAAEYIAG 88 Query: 157 YTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216 Y +A D+S +E + K D FCP+G V S+ L + +NG Sbjct: 89 YALANDVSL---PEESFYRPAIKAKCRDGFCPIGETVALSN----VDNLTIYTEINGRPA 141 Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGD 269 +TA L + LL +S TL PGD IL GTP Q +QPGD Sbjct: 142 DHWNTADLQRNAAQLLSALSEFATLNPGDAILLGTP-------QARVEIQPGD 187 >UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Salinibacter ruber DSM 13855|Rep: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Salinibacter ruber (strain DSM 13855) Length = 220 Score = 131 bits (317), Expect = 2e-29 Identities = 74/188 (39%), Positives = 103/188 (54%), Gaps = 4/188 (2%) Query: 71 APIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDW 130 +P V K+LCIG NY DH E + P PMVF K +S ++ VR+ ++ V Sbjct: 9 SPPVSVGKLLCIGRNYADHAAEMDRAVPDEPMVFLKPASALVRSGGAVRLPPQ-SQDVHH 67 Query: 131 EVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE--KNMGQFLLGKSMDTFCP 188 EVEL VVG E + AL HVAGY V D++ARD Q E + + + K DTF P Sbjct: 68 EVELVAVVGTEGKNIPRSAALDHVAGYAVGLDMTARDLQAEAKERRHPWSVAKGFDTFAP 127 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 LGP + ++ V +L + ++N +Q +ST + + L+H S + TL PGDL+ Sbjct: 128 LGP-IQPAEAVDDVQDLTLRLTVNDETRQEASTRHQIFPVRDLVHYCSHIFTLSPGDLLY 186 Query: 249 TGTPGGVG 256 TGTP GVG Sbjct: 187 TGTPSGVG 194 >UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3; Trichocomaceae|Rep: Remark: ORF contains 1 frameshift - Aspergillus niger Length = 296 Score = 128 bits (309), Expect = 2e-28 Identities = 78/219 (35%), Positives = 119/219 (54%), Gaps = 9/219 (4%) Query: 77 DKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI-RTDVTKKVDWEV-EL 134 + I C+GLNY+ H +E NL P P V++K + + PD+ + I R + DWE EL Sbjct: 65 NSIYCVGLNYRSHAKEANLNVPANPPVWTKPPAALASPDETIPISRFCASHLPDWEAGEL 124 Query: 135 CVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFCPLGPCV 193 V RE V E A Q++ GYTV D+S R +Q E++ GQF K+ D F P+GP V Sbjct: 125 VFVTSRECRDVTPEQASQYILGYTVGNDLSCRFFQLPEQSGGQFFYAKAFDKFAPIGP-V 183 Query: 194 LTSDEVGAAVELRVS--CSLNGVLKQSSSTAQ-LVHSIPSLLHRISSVMTLVPGDLILTG 250 L S +V A + +NGV+KQ + + ++ S +L +S T+ +++TG Sbjct: 184 LVSPDVFAKTRTSATLVTRINGVVKQDTVIGKDMIFSPERVLSWMSQSTTIPAYTVVMTG 243 Query: 251 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD--VRIEK 287 TP G G+++ P + L+ GD + EI +G VR E+ Sbjct: 244 TPAGAGVFQTPRQLLKDGDHIEVEISGLGTLKNVVRFEE 282 >UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Archaeoglobus fulgidus|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Archaeoglobus fulgidus Length = 324 Score = 128 bits (308), Expect = 2e-28 Identities = 81/232 (34%), Positives = 128/232 (55%), Gaps = 17/232 (7%) Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHC----QEQNLTPPP----VPMVFSKFSSTI 111 A PLS V L AP+ K++ +++H ++ ++ P VP+ + ++ Sbjct: 89 AVWPLSEVKLKAPLK--PKLMVDFSTFEEHVRMGFEKLGMSIPQEWYQVPVGYKMNPYSV 146 Query: 112 IGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-- 169 IGP++PV I T+ +D+E+E +VVG+ V +EDA+ +V GYT+ DISARD + Sbjct: 147 IGPEEPV-IWPSFTQILDYELEFGIVVGKRGKNVSKEDAMDYVLGYTIVNDISARDMEFI 205 Query: 170 --KEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHS 227 K +G L K D P+GPC++T DE+ L++ +NG + +ST + Sbjct: 206 ELKAMPLGP-LKSKDFDNATPMGPCIVTKDEIKDPHNLKMVARVNGEVWSEASTKDMHWK 264 Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 IP L+ +S T+ PG ++L+GTPGG G + L+PGDV+ EIE IG Sbjct: 265 IPDLIAHLSKDQTIHPGTVMLSGTPGG-GCGMHVGKLLKPGDVVELEIEGIG 315 >UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomer; n=10; Bacteria|Rep: 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomer - Synechocystis sp. (strain PCC 6803) Length = 276 Score = 127 bits (307), Expect = 3e-28 Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 12/202 (5%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+ +G NY+ H E P P++F K S I DQ + +++VD+E EL V+ Sbjct: 59 KIVAVGRNYRAHAAELGNDVPAEPLLFFKPPSAIAA-DQEEIVYPSQSQRVDYEGELAVI 117 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +G++ + EE+A + GYT+A DI+ARD Q++ + Q+ K D FCPLGP V+ Sbjct: 118 IGKQVKDITEEEAASAIWGYTIANDITARDLQRQDS--QWTRAKGFDGFCPLGPWVVRHI 175 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 + A +E V+ +Q+++ + +V + P L+ IS VMTL PGD+ILTGTP G+ Sbjct: 176 DPEAHLETTVND--EETPRQATAISDMVFTPPVLVSYISRVMTLYPGDVILTGTPEGISA 233 Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279 LQ GD + EIE IG Sbjct: 234 -------LQVGDKVEVEIEGIG 248 >UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - Pseudomonas abietaniphila Length = 293 Score = 127 bits (307), Expect = 3e-28 Identities = 77/227 (33%), Positives = 118/227 (51%), Gaps = 6/227 (2%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 I L+ + P+ ++ +GLNY H Q T P P+ + K S ++G ++ Sbjct: 53 IALAQCRILPPLEPGARVFGVGLNYLSHLQHLGSTAPEHPLGYIKPESALVGASDDIQYP 112 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 +T ++D+EVEL V+ R E A + GYT DISARD K L K Sbjct: 113 A-LTAQLDYEVELVAVIARALG--DEPCASACLLGYTCGNDISARDAGKRIGRLDLLTQK 169 Query: 182 SMDTFCPLGPCVLTSDEVGAA-VELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 +MD P+GP V+T DE+G L + S+N +Q +T Q++ I LL+ + + +T Sbjct: 170 AMDRTTPVGPWVVTLDEIGVGQPHLDIELSVNDECRQFDNTRQMLFPIDELLNYVDARIT 229 Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 L PGDL+ TG+ GVG+ + +LQPGD + IE IG+ R+ + Sbjct: 230 LQPGDLVFTGSTHGVGL--EDGRFLQPGDRVEVRIEGIGSMSNRVSQ 274 >UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria|Rep: Putative hydratase - Polaromonas naphthalenivorans (strain CJ2) Length = 289 Score = 127 bits (306), Expect = 4e-28 Identities = 91/291 (31%), Positives = 147/291 (50%), Gaps = 35/291 (12%) Query: 14 NIRVGYLEGDDIVDINKADSSLPT---------TLLQILRNGDLEKVKKLKSTKPATIPL 64 N R+G ++G+ + D+ A LP L+ +L LE ++++ + P T+PL Sbjct: 8 NDRLGLVDGETVRDVTAALDVLPNHRYPLPIFDPLIALLPEV-LEAIRRIAPSSP-TLPL 65 Query: 65 SSVTLTAPIHGVDKILCIGLNYKDHCQE--------QNLTPPPVPMV--FSKFSSTIIGP 114 + L AP+ K++ +NYK H QE N + + F K +S+++GP Sbjct: 66 AGRRLLAPVANPGKVIAAPVNYKKHLQEAREQVEIHHNNQVAEIEKIGLFLKATSSVVGP 125 Query: 115 DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM 174 V I+ ++ D E EL V+G+ + E A H++ YT+ D++ R Q+ Sbjct: 126 SHGVEIQHP-DRRNDHEAELVAVIGKTGRNIPRERAFDHISAYTIGLDMTVRGPQERS-- 182 Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234 L KS+DT+ +GP ++T+DE+ L ++NG +Q ++T LV IP+L+ Sbjct: 183 ----LRKSIDTYSVVGPWLVTADEIDDPQALDFWLTVNGERRQKANTRDLVLDIPALIEM 238 Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 SS TL PGDL+ TGTP GVG + GD +T EI IG +V + Sbjct: 239 ASSYYTLQPGDLLFTGTPEGVGP-------VVNGDEITVEIAGIGRMNVAV 282 >UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; n=1; Pseudomonas alcaligenes|Rep: Putative uncharacterized protein xlnF - Pseudomonas alcaligenes Length = 287 Score = 126 bits (304), Expect = 7e-28 Identities = 77/233 (33%), Positives = 126/233 (54%), Gaps = 23/233 (9%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP-----PPVPMV-----FSKFSSTIIG 113 L +VTL +P+ KI+ +NY DH E N + ++ F K S+ +G Sbjct: 68 LDAVTLISPVGNPGKIIAAPVNYADHLDESNQDKGINFGTEISLIDKYALFLKAGSSSVG 127 Query: 114 PDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKN 173 PD+ + + ++ D EVEL +V+G+E V ++AL VAGY + DI+ R + Sbjct: 128 PDEGISLPAVEGRRFDHEVELALVIGKETRRVTVDEALSSVAGYFIGLDITMRGTEDRSY 187 Query: 174 MGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLH 233 KS D+F +GP ++TSD G+ + S S+NG +Q+++T LV S+ ++ Sbjct: 188 R------KSFDSFTVMGPWLVTSDAFGSPEGVAFSLSVNGEQRQNANTNDLVWSVAKIIS 241 Query: 234 RISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286 S TL PGD+ILTGTP GVG ++ GD +++ I++IG+ +V ++ Sbjct: 242 VASHAYTLYPGDVILTGTPAGVGP-------IKAGDKISASIDRIGSMEVPVK 287 >UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; Eukaryota|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 228 Score = 126 bits (304), Expect = 7e-28 Identities = 74/186 (39%), Positives = 105/186 (56%), Gaps = 6/186 (3%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ-PVRIRTDVTKKVDWEVELCV 136 KI+ IG NY DH +E P P F K +S+ + PD PV I V V EVEL V Sbjct: 10 KIVAIGRNYADHAKELGNAIPKEPFFFLKPTSSYLVPDNGPVEIPRGVI--VHHEVELGV 67 Query: 137 VVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMG-QFLLGKSMDTFCPLGPCVL 194 V+G+ + A HVAGY++A D++AR+ Q K K G + K DTFCP+GP + Sbjct: 68 VIGKNGRDISPSAAFDHVAGYSLAVDMTARNVQDKAKAKGLPWSAAKGFDTFCPIGPFI- 126 Query: 195 TSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGG 254 + ++ + S+NG +KQS T+ ++ IP L+ +S +M L GDL+LTGTP G Sbjct: 127 PKHFIADPTKVGLHFSVNGTVKQSGLTSDMIFDIPQLIAFVSGIMKLEEGDLVLTGTPSG 186 Query: 255 VGMYRQ 260 VG ++ Sbjct: 187 VGKIKR 192 >UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 312 Score = 126 bits (303), Expect = 9e-28 Identities = 71/226 (31%), Positives = 127/226 (56%), Gaps = 12/226 (5%) Query: 64 LSSVTLTAPIHGVDK-ILCIGLNYKDHCQEQNLTPPPV-------PMVFSKFSSTIIGPD 115 L+ +TL API + ++C+G+NY +H +E + + FSK + + Sbjct: 82 LADITLLAPIPKPKQDVICLGINYLEHAKESAAYKNEIFDQKRENAVYFSKRVNYATPHN 141 Query: 116 QPVRIRTDVTKKVDWEVELCVVVGREASCVRE-EDALQHVAGYTVAQDISARDWQKEKNM 174 P+ + +++T+K+D+EVEL VV+G + ++ + + GYT+ DIS+RD Q++ Sbjct: 142 APIPLHSNLTQKLDYEVELGVVLGSHLYKPKNMQEVIDSIFGYTIINDISSRDIQQKHK- 200 Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234 Q+ +GKS++ P+GPC++++ + A L + +NG L+Q S T+ ++ +I + L+ Sbjct: 201 -QWYMGKSLEGSLPMGPCIVSARSIDAQ-NLAIKSYVNGELRQDSHTSLMICNITAALYE 258 Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280 +S L +I GTP GVGM PP +L D + EI+ IG+ Sbjct: 259 LSHYCMLQAASIISMGTPSGVGMGFNPPRFLSNNDEIVCEIQHIGS 304 >UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate isomerase; n=1; Thermoplasma volcanium|Rep: 2-hydroxyhepta-2,4-diend-1,7-dioate isomerase - Thermoplasma volcanium Length = 268 Score = 124 bits (300), Expect = 2e-27 Identities = 69/211 (32%), Positives = 115/211 (54%), Gaps = 7/211 (3%) Query: 72 PIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWE 131 P KI +N++ H E + PP P F+KFS+ ++ + +R + KK+D+E Sbjct: 55 PAVNPQKIFLPAVNFRSHSAESDTRFPPKPYFFTKFSNALVANNSELRTPGTI-KKLDYE 113 Query: 132 VELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ--KEKNMG-QFLLGKSMDTFCP 188 E V+G++ + EDA + G+T+A D+SARD+Q + G ++ GK+ D P Sbjct: 114 GETGAVIGKKCYNIPAEDAYDCIFGFTIANDLSARDFQFPEMHPYGYNWVQGKAFDGALP 173 Query: 189 LGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 +GP + T DE+ +E+ +NG +Q +T +V S L+ +S +TL PGD+I Sbjct: 174 VGPYITTKDEIQFPLEIETK--VNGETRQKGTTDDMVFSFQDLISTLSQNITLEPGDIIT 231 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +GTP GV + + YL+ GDV+ + +G Sbjct: 232 SGTPAGVAAFSE-KLYLKSGDVIEISVSSLG 261 >UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; Eukaryota|Rep: Uncharacterized protein ZK688.3 - Caenorhabditis elegans Length = 214 Score = 124 bits (300), Expect = 2e-27 Identities = 69/180 (38%), Positives = 105/180 (58%), Gaps = 4/180 (2%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+C+G NYKDH E P PM+F K ++ I +P+ + + + EVEL VV Sbjct: 13 KIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEGEPI-VAPPGCQNLHQEVELGVV 71 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLGPCVLT 195 + ++AS + + DA+ ++ GYTVA D++ARD+Q E K G + L KS D CP+G + Sbjct: 72 ISKKASRISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGSCPIGGFLPV 131 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 SD + ++ + C +NG +Q T ++ IP+LL + TL GD++LTGTP GV Sbjct: 132 SD-IPNPHDVELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEVGDVVLTGTPAGV 190 >UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / 5-carboxymeth..; n=42; Bacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / 5-carboxymeth.. - Yersinia pseudotuberculosis Length = 254 Score = 124 bits (299), Expect = 3e-27 Identities = 73/207 (35%), Positives = 110/207 (53%), Gaps = 9/207 (4%) Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138 + +GLNY DH E + +PP P++F K + G Q V +R D + + +E EL VVV Sbjct: 46 LFALGLNYVDHAAELDFSPPKEPLIFIKAPHSFTGHRQ-VSVRPDNIEYMHYEAELVVVV 104 Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE 198 G+ A + A+ +VAGYT+ D + RD+ E L KS DT P+GP ++ + Sbjct: 105 GKPARYLNPAHAMDYVAGYTLCNDYAVRDYL-ENYYRPNLRVKSRDTLTPIGPWIVDKAD 163 Query: 199 VGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMY 258 + L + +NG L Q +TA L+ IP L+ +S +TL PGD+I TGTP G+ Sbjct: 164 IPNPHNLVIRTWVNGELCQRGNTADLIFDIPFLMAYLSEFITLQPGDMIATGTPKGL--- 220 Query: 259 RQPPEYLQPGDVLTSEIEKIGAFDVRI 285 + PGD + E++ IG R+ Sbjct: 221 ----SNVVPGDEVVVEVDGIGCLLNRV 243 >UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Bacillus coagulans 36D1|Rep: Fumarylacetoacetate (FAA) hydrolase - Bacillus coagulans 36D1 Length = 278 Score = 123 bits (297), Expect = 5e-27 Identities = 92/280 (32%), Positives = 138/280 (49%), Gaps = 25/280 (8%) Query: 17 VGYLEGDDIVDINKA---DSSLP-TTLLQILRNGDLEKVK-KLKSTKPATIPLSSVTLTA 71 +G + GD I DI+K D + P + L+++ + D K + + + PL+ VTL Sbjct: 11 LGAVTGDRITDISKVTNWDRNDPHASFLKLMAHYDEWKENIEQEIASGVSYPLNGVTLKC 70 Query: 72 PIHGVDKILCIGLNYKDHCQEQNLTPPPVPM------VFSKFSSTIIGPDQPVRIRTDVT 125 P+ G KI +NY H +E N P +F K ++ GP P+ I Sbjct: 71 PVPGAGKIWAAPVNYLKHQEEMNHQFNNAPRTIEELSLFLKSPQSLSGPTDPI-ILPFPE 129 Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDT 185 ++ D E EL +VG++A V+ +A ++ GY DIS R +E+ KS DT Sbjct: 130 RRTDHEAELGYIVGKKAKNVKAREAKDYIFGYFALLDISIRG-NEERTWR-----KSFDT 183 Query: 186 FCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245 F P+GP ++T DE+ +L +S +N L+QS ST L++ MTL PGD Sbjct: 184 FTPIGPWIVTEDEIKNPNDLAISLWVNDELRQSGSTKYLIYDCYKCFELACDHMTLHPGD 243 Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 +I TGTP GVG R+ GD + IE+IG F V + Sbjct: 244 IIATGTPEGVGPIRE-------GDRVKISIEQIGEFTVDV 276 >UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Solibacter usitatus Ellin6076|Rep: Fumarylacetoacetate (FAA) hydrolase - Solibacter usitatus (strain Ellin6076) Length = 252 Score = 122 bits (295), Expect = 8e-27 Identities = 81/221 (36%), Positives = 111/221 (50%), Gaps = 15/221 (6%) Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVR 119 AT+ LS V L P KIL +GLNYK H + P P +F K S + P P+ Sbjct: 39 ATLKLSDVKLLYPCEA-GKILAVGLNYKSHLGSR--PQPAHPEMFYKPISALQNPGDPIE 95 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-EKNMGQFL 178 + D T V E E+ VVVG ++A V G T D+S R WQ EK Q+ Sbjct: 96 LPRDATD-VHSEGEMVVVVGGYLRNASVDEAADAVFGVTCGNDVSDRSWQHGEKKDLQWW 154 Query: 179 LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238 K DTF PLGP +++ + G +L + +NG Q T+ L+ IP++L IS Sbjct: 155 RAKGSDTFAPLGPAIVSGVDYG---KLLLQTRINGETVQKQFTSDLIFDIPTVLSWISGW 211 Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +TL PGDL+ TGTPG + PGD++ E+E +G Sbjct: 212 VTLFPGDLVYTGTPGNT-------RKMSPGDLVEVELEGVG 245 >UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 325 Score = 122 bits (293), Expect = 1e-26 Identities = 73/220 (33%), Positives = 112/220 (50%), Gaps = 18/220 (8%) Query: 76 VDKILCIGLNYKDHCQEQNLT-PPPVPMVFSKFSSTIIGP------DQPVRIRTDVT--- 125 V K+L NY DH + T P +P+ + P + P D+ Sbjct: 92 VGKMLFAAANYSDHVRNMRKTFTPDIPLADQGKQLPPLRPYMFGKINVPTGAFDDIILPP 151 Query: 126 --KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD--WQKEKNM--GQFLL 179 +++DWE EL VV+G +R +A +H+AGY D+S RD W++++ +L Sbjct: 152 GMERIDWEAELMVVIGTPGLAIRPAEAHRHIAGYMTGNDVSCRDRTWREDRPTIRSDWLG 211 Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239 GKS D+F PLGP + V +L + +NG LKQ ++ + I + SS+M Sbjct: 212 GKSYDSFAPLGPLLTPRQFVPDHADLAIRLWVNGELKQDGNSRDMTFGIEEQIEYASSMM 271 Query: 240 TLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 TL+PGD+I TGTP G G R E+L+ GD++ +E+E G Sbjct: 272 TLLPGDVIATGTPAGTGQER--GEFLKEGDIVETEVESCG 309 >UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 343 Score = 121 bits (291), Expect = 2e-26 Identities = 70/183 (38%), Positives = 103/183 (56%), Gaps = 7/183 (3%) Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160 P F K S+I+GP + + D ++++DWE+EL VV+G+ A V + AL HVAGY V Sbjct: 137 PFAFLKPFSSILGPFDDLAVPAD-SEQLDWELELGVVIGKPARRVGRDRALDHVAGYVVV 195 Query: 161 QDISARDWQKEKNMGQFLL----GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216 DIS RD ++ Q L GKS P+GP ++ + V +L ++ LNG + Sbjct: 196 NDISVRDHLYRPDVPQLGLDWVSGKSGPGMLPMGPLIVPAAFVADPQQLMITLKLNGEVM 255 Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276 Q STA ++ I L+ S M L+PGD+I TG+P G G + +L+PGDV+ IE Sbjct: 256 QHESTADMIFPIARLIEAFSVHMQLLPGDIICTGSPSGNGTHF--GRFLRPGDVMEGTIE 313 Query: 277 KIG 279 +G Sbjct: 314 GLG 316 >UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 255 Score = 120 bits (288), Expect = 6e-26 Identities = 80/217 (36%), Positives = 114/217 (52%), Gaps = 14/217 (6%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123 L V L +P+ K++ IG NY D + P P +F K +++++GPD P+ I Sbjct: 45 LDEVRLLSPVIPRSKVVGIGDNYSDTPIPADERPEPP--IFLKANTSVVGPDDPIAIPA- 101 Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSM 183 + V +E EL +V+ A V EDA Q + GYT+A D +ARD G + GKS Sbjct: 102 WSNAVAFEGELAIVIKSLAKDVSVEDAPQMILGYTIANDATARD---AMTGGPWSRGKSF 158 Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243 D+ CPLGP + T D L + LNG + Q SSTA ++ + L+ +S MTL+P Sbjct: 159 DSACPLGPWI-TVDPALDVTNLAIRSYLNGEIAQDSSTAHMIWNPFELVSYLSHQMTLLP 217 Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGA 280 GD+I TG P G E + GD + EIE IG+ Sbjct: 218 GDVIATGAPAGA-------EIVHAGDRVEIEIEGIGS 247 >UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; Eurotiomycetidae|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 327 Score = 120 bits (288), Expect = 6e-26 Identities = 68/232 (29%), Positives = 118/232 (50%), Gaps = 6/232 (2%) Query: 51 VKKLKSTKPAT-IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSS 109 ++ L+S +T + + + P+ G++ I+C+GLNY++H E +L P P ++ K Sbjct: 91 IEALESDGQSTNVTVEKLLAPVPVTGIN-IICVGLNYRNHANEASLPIPTCPPMWYKAPP 149 Query: 110 TIIGPDQPVRIRTDVTKKV-DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW 168 + PD + + K D+E EL +V+ + +A H+ GYT+ D++AR + Sbjct: 150 ALADPDSEIPVPPQAQKSFPDFEGELTIVLRNTIKSISASEATSHILGYTIGNDLTARFF 209 Query: 169 QKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAA-VELRVSCSLNGVLKQSSSTAQLVHS 227 Q+ GQ+ K D F PLGP ++ + R++ +NG + Q S + Sbjct: 210 QRACG-GQYTHAKGFDNFAPLGPRLVHPSVFSPSDASRRITTRVNGRVVQDSPF-DFIFP 267 Query: 228 IPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + L+ +S T+ G I+TGTP GVG ++ P LQ GD + E++ IG Sbjct: 268 VDELVSFLSEGTTIPAGTAIMTGTPAGVGWFQDPKCPLQHGDAVEVEVQPIG 319 >UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Serratia proteamaculans 568 Length = 287 Score = 119 bits (286), Expect = 1e-25 Identities = 79/233 (33%), Positives = 122/233 (52%), Gaps = 24/233 (10%) Query: 63 PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL----------TPPPVPMVFSKFSSTII 112 PL V+L AP+ KI+ +NY+DH E N T +F K +S++ Sbjct: 64 PLEQVSLNAPVANPGKIVAAPINYRDHIAEANADQQINHGKVYTDISEYGLFLKANSSLC 123 Query: 113 GPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEK 172 GP++ + + ++ D EVEL V++G+ A + + AL+ V GY + D++ R + Sbjct: 124 GPNEIIPLPIP-GRRTDPEVELAVIIGQRARNLPVDQALEAVFGYAIGIDMTVRGSEFPS 182 Query: 173 NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLL 232 KS D F LGP ++T DE+G L +S +NG L+Q S+T L++++ L+ Sbjct: 183 ------FRKSADGFSVLGPWIVTPDEIGDPNTLDLSIRVNGQLRQHSNTRHLIYNVQRLI 236 Query: 233 HRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 S++ TL PGD+I TGTP GV +Q GD + IE+IGA V I Sbjct: 237 AYASAMFTLWPGDVIYTGTPSGVSA-------IQAGDRIEVSIERIGAMSVTI 282 >UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate (FAA) hydrolase - Sphingomonas wittichii RW1 Length = 329 Score = 118 bits (285), Expect = 1e-25 Identities = 67/190 (35%), Positives = 105/190 (55%), Gaps = 7/190 (3%) Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160 P VF+K +T+ G + + + + TK DWE+EL VV+GR + E A++HVAGY + Sbjct: 139 PYVFTKPITTVAGANDTLILPANTTKP-DWELELAVVIGRGGIRIPREAAMEHVAGYAIV 197 Query: 161 QDISARDW---QKEKNMG-QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216 D+SARD K +G +L K + F P GP ++ + + LR+ S+ G + Sbjct: 198 NDVSARDLIPRTDYKLLGTDWLRSKGQEGFLPFGPYMVPARFIADPYALRIRLSVEGQMM 257 Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276 Q +TA ++ I + IS L+PGD+I TG+P G G + +LQ GD++ EI+ Sbjct: 258 QDETTADMMFDIARQIEYISRYSRLLPGDVICTGSPAGNGTHYN--RFLQDGDLMIGEID 315 Query: 277 KIGAFDVRIE 286 +GA +R E Sbjct: 316 GLGAQRIRCE 325 >UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the fumarylacetoacetate hydrolase family; n=6; Bifidobacterium|Rep: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the fumarylacetoacetate hydrolase family - Bifidobacterium longum Length = 292 Score = 118 bits (284), Expect = 2e-25 Identities = 76/221 (34%), Positives = 118/221 (53%), Gaps = 14/221 (6%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMV-FSKFSSTIIGPDQPVRI 120 I L S + + ++G+ K + + P MV F+K S+++IGPD P+ + Sbjct: 74 IRLLSPVIPSKVYGLAKNYEAHAQFMHEAGHSEIAHAPEDMVIFTKPSTSVIGPDDPI-V 132 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 +K +++E E+ VV+GR A V E+A+ +V G+T D++ RD Q + Sbjct: 133 YPACSKDMNFEPEVAVVMGRIAKNVTVENAMDYVLGFTCVNDVTLRDLQGIDPT--WTRA 190 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNG--VLKQSSSTAQLVHSIPSLLHRISSV 238 K DT CPLGP ++ D++ + ++S +LNG V S +TA L+H IP + ISS Sbjct: 191 KGFDTSCPLGPWIVMRDDLDWK-DAKISFTLNGEDVPMASGTTANLIHGIPEQIAAISSF 249 Query: 239 MTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 TL+PGD+I+TGTP G +L PGD +E IG Sbjct: 250 STLLPGDVIMTGTPNASG-------HLDPGDETIVHVEGIG 283 >UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase-related protein; n=4; Deinococci|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase-related protein - Deinococcus radiodurans Length = 250 Score = 118 bits (283), Expect = 2e-25 Identities = 79/228 (34%), Positives = 122/228 (53%), Gaps = 17/228 (7%) Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQ-NLTP--PPVPMVFSKFSSTIIGPDQP 117 T+ LS L AP KI+C+G NY DH +E N T P P +F K + + P Sbjct: 36 TLALSEARLLAPAEP-SKIVCVGRNYLDHIRELGNDTGDLPAEPGIFLKGPNALAEPGGT 94 Query: 118 VRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF 177 V + ++ +E EL +V+G+ A ++ ++AL V GYT D++ARD QK Q+ Sbjct: 95 VEYPS-WSENFHFEGELALVIGQRARNLKADEALGAVLGYTCGLDLTARDRQKTDL--QW 151 Query: 178 LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237 K+ D FCPLGP ++T + ++RV +NG +Q T+ ++ + +L ++ Sbjct: 152 FRAKAADRFCPLGPWLVTQFDPS---DVRVQTRVNGEPRQDGRTSHMIFDVVQILTYLTR 208 Query: 238 VMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 +TL PGD++LTGTP GVG LQ GD + E++ IG + I Sbjct: 209 FVTLEPGDVVLTGTPEGVGP-------LQRGDRVEVEVDGIGVLETFI 249 >UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gammaproteobacteria|Rep: Uncharacterized protein ycgM - Escherichia coli (strain K12) Length = 219 Score = 118 bits (283), Expect = 2e-25 Identities = 73/199 (36%), Positives = 104/199 (52%), Gaps = 10/199 (5%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 V K++C+G NY H +E P P++F K + + QP+ I +D V EVEL Sbjct: 16 VSKVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFGS-VHHEVELA 74 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQ-FLLGKSMDTFCPLGPCV 193 V++G EE + +AGY VA D++ RD Q K K GQ + K+ D CPL + Sbjct: 75 VLIGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFI 134 Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253 ++ G +S S+NG +Q +TA ++H I L+ +S TL GD++LTGTP Sbjct: 135 PAAEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPD 194 Query: 254 GVGMYRQPPEYLQPGDVLT 272 GVG LQ GD LT Sbjct: 195 GVGP-------LQSGDELT 206 >UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Corynebacterium|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 268 Score = 116 bits (280), Expect = 5e-25 Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 17/223 (7%) Query: 63 PLSSVTLTAPIHGVDKILCIGLNYKDHCQE--QNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 PL V L AP+ K++ IG NY DH E + P +F K + + GP+ P+RI Sbjct: 48 PLKDVRLLAPMLP-SKVVAIGRNYADHVAEVFKKSAESLPPTLFLKPPTAVTGPESPIRI 106 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 + TK V++E EL VV+G+ V+ +D V G+T+ D+S+RD Q GQ+ Sbjct: 107 PSFATK-VEFEGELAVVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFAD--GQWARA 163 Query: 181 KSMDTFCPLGPCVLTS----DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 K +DTF P+GP + T D ++ R++ LKQ S++ Q++ + ++ I+ Sbjct: 164 KGIDTFGPIGPWIETDINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFIT 223 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + MTL+PGD+I TG+P G E + GD + EI IG Sbjct: 224 ASMTLLPGDVIATGSPAGT-------EAMVDGDYIEIEIPGIG 259 >UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Silicibacter pomeroyi|Rep: Fumarylacetoacetate hydrolase family protein - Silicibacter pomeroyi Length = 281 Score = 116 bits (279), Expect = 7e-25 Identities = 70/223 (31%), Positives = 108/223 (48%), Gaps = 7/223 (3%) Query: 60 ATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP-PVPMV-FSKFSSTIIGPDQP 117 A +PL S+ PI KILC G+NY+ + PP P +V FS+ T++G Sbjct: 54 AALPLDSLVWLPPIPAPGKILCAGMNYRKPYPVAGVAPPDPGHVVLFSRHPQTLVGHGAM 113 Query: 118 VRI-RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ 176 + + + + D+E E+ V+G+ + E AL HV GY+ + S R W K Sbjct: 114 LEMPQGAAAESFDFEGEIVAVIGQPGRHIAPEAALGHVLGYSAMNEGSVRGWMKHSVHA- 172 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 GK+ GP + T+DE G + + +NG QS S A ++ + L+ IS Sbjct: 173 ---GKNFHASGSWGPWITTADEAGDIAGMTLETRVNGTPMQSDSGAGMIFGLAELIAYIS 229 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 + L GD+I TG+P G G R PP +L+ GD + + +G Sbjct: 230 HIQPLEAGDIIATGSPDGTGGSRTPPAFLRSGDRVAVTVGGVG 272 >UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Comamonas testosteroni KF-1 Length = 289 Score = 116 bits (279), Expect = 7e-25 Identities = 73/220 (33%), Positives = 113/220 (51%), Gaps = 18/220 (8%) Query: 72 PIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTII----GPDQPVRIRTDVTKK 127 PIH +I C+G NY+DH +E T P F K + + G V T +T+ Sbjct: 81 PIH---RIYCVGRNYEDHAKEMGFTGREPPFFFMKPADATVALEAGSTGQVAYPT-LTQN 136 Query: 128 VDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDT 185 + E+EL V +G+ ++ DALQ++ GY V D++ RD Q E K G+ + +GK+ + Sbjct: 137 LHHEIELVVAIGKAGKNIKAADALQYIYGYAVGLDMTRRDLQNEMKKQGRPWCIGKAFEQ 196 Query: 186 FCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245 P+GP + +D+ G +S +NG +Q S +L+ +I + +SS L PGD Sbjct: 197 SAPIGP-ITPADQAGDIANAEISLQVNGDYRQRSHIHKLIWNIAETIEHLSSAWELQPGD 255 Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 LI+TGTP GV + GDVL I + A ++I Sbjct: 256 LIMTGTPEGVAA-------VVKGDVLEGAITGLEAIRIQI 288 >UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Gammaproteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Enterobacter sp. 638 Length = 219 Score = 116 bits (278), Expect = 9e-25 Identities = 66/183 (36%), Positives = 97/183 (53%), Gaps = 3/183 (1%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 V K++C+G NY H QE P P++F K + + QP+ + + V EVEL Sbjct: 16 VSKVVCVGSNYAKHIQEMGSAVPDEPVLFIKPETALCDIRQPLALPQGLGS-VHHEVELA 74 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQ-FLLGKSMDTFCPLGPCV 193 V++G EE + +AGY +A D++ RD Q K K GQ + K D CP+ + Sbjct: 75 VLIGATLRQASEEHVQKAIAGYGIALDLTLRDVQGKMKKAGQPWEKAKGFDNSCPISGFI 134 Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253 T+D +S +NG ++Q +TA ++H I L+ +S TL PGD+ILTGTP Sbjct: 135 PTADFKADPQNTSLSLKVNGDIRQQGNTADMIHKILPLIAYMSRYFTLKPGDVILTGTPE 194 Query: 254 GVG 256 GVG Sbjct: 195 GVG 197 >UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep: MelH protein - Melittangium lichenicola Length = 329 Score = 115 bits (276), Expect = 2e-24 Identities = 73/233 (31%), Positives = 119/233 (51%), Gaps = 10/233 (4%) Query: 38 TLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP 97 TL L G + + + T+ + V L +P+ ++C G NY+ H E P Sbjct: 33 TLAGFLGEGAAHARRLAAAPEGETLAVRDVELLSPVTAPCNVVCQGQNYRSHMLEVGQDP 92 Query: 98 PP--VPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREAS--CVREEDAL-Q 152 F K SS++ + ++ + + +D+E+EL +V+GR S C E + L + Sbjct: 93 EAKNFNQFFRKASSSLTSGHGDI-VKPERVRMLDYEIELGLVIGRPLSGPCRVERERLHE 151 Query: 153 HVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCV--LTSDEVGAAVELRVSCS 210 VAG + D+SARD Q + GQ+ KS TFCP GP + L +++ + L++ S Sbjct: 152 FVAGLVICNDVSARDIQLAE--GQWYKSKSFRTFCPAGPYLYLLDAEDNARVMNLKLHLS 209 Query: 211 LNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPE 263 +N +Q S+T+++V+ L +S VM L PGDL++TGTP GV P+ Sbjct: 210 VNDQTRQDSNTSEMVYPPEETLSELSEVMDLFPGDLVMTGTPRGVAAGHNAPK 262 >UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-containing protein 1; n=21; Eumetazoa|Rep: Fumarylacetoacetate hydrolase domain-containing protein 1 - Homo sapiens (Human) Length = 224 Score = 113 bits (273), Expect = 4e-24 Identities = 65/187 (34%), Positives = 103/187 (55%), Gaps = 4/187 (2%) Query: 79 ILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVV 138 I+C+G NY DH +E P++F K ST P+ + T+ + E+EL VV+ Sbjct: 20 IVCVGRNYADHVREMRSAVLSEPVLFLK-PSTAYAPEGSPILMPAYTRNLHHELELGVVM 78 Query: 139 GREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLGPCVLTS 196 G+ V E A+ +V GY + D++ARD Q E K G + L KS CP+ V Sbjct: 79 GKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAFV-PK 137 Query: 197 DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVG 256 +++ +L++ +NG L+Q T+ ++ SIP ++ +S ++TL GD+ILTGTP GVG Sbjct: 138 EKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVG 197 Query: 257 MYRQPPE 263 ++ E Sbjct: 198 PVKENDE 204 >UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family protein; n=13; Bacillus|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus anthracis Length = 318 Score = 113 bits (272), Expect = 5e-24 Identities = 86/303 (28%), Positives = 143/303 (47%), Gaps = 19/303 (6%) Query: 1 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKA-DSSLPTTLLQILRNGD--LEKVKKLKST 57 MK V F K +R G+LEGD ++D+N A D LP+++ L D +E ++ +K+ Sbjct: 1 MKFVTFRLPS--KEMRAGWLEGDKVIDMNLASDGKLPSSMFAFLEKADEYVEVLRNIKNP 58 Query: 58 KPATIPLSSVTLTAPIHGVDKI---LCIGLNYKDHCQEQNLTPPP----VPMVFSKFSST 110 + L V L A I I + K + L P +P+ + Sbjct: 59 EKGIYSLEEVQLAAAIPNPSSIRDFYAFEQHVKTARGRRGLDVVPEWYDIPVFYFTNHRA 118 Query: 111 IIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170 +IGP+ V I ++K+D+E+E+ V+G+E + E A +++ GY + D SARD Q Sbjct: 119 VIGPNDVV-IGPKKSEKIDYELEIACVIGKEGRNISREQAEEYIFGYCIMNDWSARDLQA 177 Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEV-----GAAVELRVSCSLNGVLKQSSSTAQLV 225 + K D LG ++T +E+ G EL ++ +NG L + + Sbjct: 178 TEMKVGLGPAKGKDFATSLGAHLVTKEELDVYRNGDRYELEMTAHVNGKLLSKGNFQDIY 237 Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPG-GVGMYRQPPEYLQPGDVLTSEIEKIGAFDVR 284 ++ ++ R S +TL PGD+I +GT G G + E+LQ GDV+ I +G Sbjct: 238 YTFAEMIERASEDVTLYPGDVIGSGTVGTGCILELGTEEWLQDGDVVELTITGLGTLRNT 297 Query: 285 IEK 287 ++K Sbjct: 298 VKK 300 >UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Mycobacterium sp. JLS|Rep: Fumarylacetoacetate (FAA) hydrolase - Mycobacterium sp. (strain JLS) Length = 265 Score = 113 bits (271), Expect = 7e-24 Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 8/222 (3%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMV-FSKFSSTIIGPDQPVRI 120 + L V L PI ++ +G+NY H ++ +T P + F K + IIG V Sbjct: 37 LKLDDVRLLPPITPTSTVVGVGMNYWSHLEKLGVTERPKSTLGFLKPRAAIIGHGD-VLA 95 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 +T+++D+EVEL VV+ + S + V GYTV D+SARD + G L Sbjct: 96 NPVITEQLDFEVELVVVLAQSVSHPGGRPT-EAVLGYTVGNDVSARDAAVPMSGGLDLFS 154 Query: 181 -KSMDTFCPLGPCVLTSDEVGAAVELRVSCSL--NGVLKQSSSTAQLVHSIPSLLHRISS 237 K++ P+GP + T DE G + ++ V SL NG +Q T +++ SI L + + Sbjct: 155 IKALGGTTPVGPWITTKDEFGGSGQIDVGISLRVNGEQRQHDRTGKMIFSIDECLDYVVA 214 Query: 238 VMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 M L GD++ TGT GVG + YLQ GDV+ +E+E +G Sbjct: 215 RMPLAAGDIVFTGTTHGVGF--EDGRYLQAGDVVEAEVEGVG 254 >UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Aeropyrum pernix|Rep: Fumarylacetoacetate hydrolase family protein - Aeropyrum pernix Length = 286 Score = 113 bits (271), Expect = 7e-24 Identities = 65/190 (34%), Positives = 104/190 (54%), Gaps = 6/190 (3%) Query: 82 IGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGRE 141 +G +Y +H +E ++ FSK +++ G PV + V++K D+E E+ +++G+ Sbjct: 82 VGRSYAEHAREMGMSKQIA--FFSKPVTSLTGHLNPVVV-PPVSEKPDYEGEIVIIIGKR 138 Query: 142 ASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGA 201 +A + +AGYT DI+ R Q +M + + K +DT+ P+GP D Sbjct: 139 IKNASTAEAGKAIAGYTAGADITDRLLQ---DMMSWSMAKGLDTYGPVGPVATIIDSPDD 195 Query: 202 AVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP 261 L V LNG Q T ++ SIP ++ R+S++ TL PGD++ TGTP GVG R+P Sbjct: 196 LDGLCVHTWLNGEKVQRGCTGDMIVSIPDMVSRLSALATLRPGDIVFTGTPPGVGHARKP 255 Query: 262 PEYLQPGDVL 271 P YL+ GD L Sbjct: 256 PRYLRHGDEL 265 >UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Thermosinus carboxydivorans Nor1|Rep: Fumarylacetoacetate (FAA) hydrolase - Thermosinus carboxydivorans Nor1 Length = 295 Score = 111 bits (267), Expect = 2e-23 Identities = 73/213 (34%), Positives = 107/213 (50%), Gaps = 6/213 (2%) Query: 44 RNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE-QNLTPPPVPM 102 RNG EK L+S I + V KI IGLNY DH + P P Sbjct: 57 RNGGKEK---LESLSQYAISKNEVRYAPLYRHPSKIWGIGLNYVDHAGDLAEKAPTLAPA 113 Query: 103 VFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQD 162 F+KF +TIIGP + ++I ++K E EL ++ G++ V E+D L VAG+T D Sbjct: 114 SFAKFDTTIIGPGEEIKIPLQ-SEKTTGESELAIIFGKKCKDVEEKDWLNVVAGFTTIID 172 Query: 163 ISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTA 222 ++A D + N K+ DTF GP ++T DE+ +L V+ +NG + + + Sbjct: 173 MTAEDILRI-NPRYLTRAKNFDTFLSFGPVLVTPDEIEDVNKLNVATVINGRIHARNVVS 231 Query: 223 QLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 + L+ S V T++PGD+ILTGTP V Sbjct: 232 NMTFPPAYLVSFHSKVATMLPGDIILTGTPRAV 264 >UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Gammaproteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - marine gamma proteobacterium HTCC2143 Length = 223 Score = 111 bits (267), Expect = 2e-23 Identities = 70/200 (35%), Positives = 107/200 (53%), Gaps = 12/200 (6%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+C+G NY DH +E N P P++F K S+ + P+ I TD E+E+ V+ Sbjct: 23 KIVCVGRNYADHAKELNNPIPDRPLLFIKPSTAAVDMLLPINIPTD-RGCCHHELEMAVL 81 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCVLT 195 +G+ +S V +A + G + D++ RD Q E K G+ + K+ D CPL P Sbjct: 82 IGKRSSSVSSVEAKDAIVGVGLGLDLTLRDLQDELKAKGEPWERAKAFDGSCPLSPFSSV 141 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 D L ++ NG ++QS +T ++ + L+ IS TL+PGD+ILTGTP GV Sbjct: 142 GDI--DQQNLNITLLRNGTVQQSGNTRDMLFPVADLIADISRSFTLLPGDIILTGTPAGV 199 Query: 256 GMYRQPPEYLQPGDVLTSEI 275 G P Y PGD +T+++ Sbjct: 200 G-----PLY--PGDTITAQL 212 >UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifunctional isomerase : decarboxylase; n=2; Bacillaceae|Rep: 4-hydroxyphenylacetate degradation bifunctional isomerase : decarboxylase - Oceanobacillus iheyensis Length = 263 Score = 110 bits (264), Expect = 5e-23 Identities = 78/256 (30%), Positives = 125/256 (48%), Gaps = 21/256 (8%) Query: 40 LQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNL---- 95 +Q L+ G + +KL L ++L PI+G + LNYK E Sbjct: 11 VQQLKEGIYQPDQKLLKFDGKQCSLDDLSLDVPINGT--VYGTLLNYKGEYAELESSMNE 68 Query: 96 ----TPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDAL 151 TPP P+++ K +T IG + + V +KV L VV+G+ A +R+E+AL Sbjct: 69 DPYKTPPKAPILYIKPINTHIGYGMTIPLPEGV-EKVSIGAALGVVIGKPAKNIRKENAL 127 Query: 152 QHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSL 211 +VAGYT+ D+S + E K+ D FCP+GP VL D + EL + + Sbjct: 128 DYVAGYTIVNDVSIPN---ESYYRPAYKEKARDGFCPIGPWVLRRDAIENPNELGIRVYI 184 Query: 212 NGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVL 271 NG +KQ ++T+ L+ S+ L+ ++ MTL GD++L G P + ++ D + Sbjct: 185 NGEIKQENTTSNLIRSVEQLMEEVTDFMTLYEGDVLLVGVPENAPIAKE-------NDRV 237 Query: 272 TSEIEKIGAFDVRIEK 287 EI+ IG ++EK Sbjct: 238 IIEIDNIGTLVNKVEK 253 >UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Plesiocystis pacifica SIR-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Plesiocystis pacifica SIR-1 Length = 287 Score = 110 bits (264), Expect = 5e-23 Identities = 75/228 (32%), Positives = 106/228 (46%), Gaps = 12/228 (5%) Query: 51 VKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSST 110 V + ++ PA + AP K+L IG NY H +E P P+ F K S Sbjct: 55 VAEAQALGPAQTLFEDQAVLAPPLAPTKVLAIGRNYAAHAKELGNEVPSSPLSFFKPPSC 114 Query: 111 IIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK 170 ++ QP+ + + +D E EL +V+GR A + DA HV Y + DIS RD Q+ Sbjct: 115 LLASGQPLSLPRGYAR-IDMEAELVLVIGRRARQIAAADAWAHVGAYLMGNDISCRDLQR 173 Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSD--EVGAAVELRVSCSLNGVLKQSSSTAQLVHSI 228 Q+ K D F P+ S E+ LRV L L Q T+ ++ + Sbjct: 174 SDK--QWTRAKGFDGFGPVSAFARLSPAAELPPVDALRVRGLLGDELVQDGPTSAMIFDV 231 Query: 229 PSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276 P+LL +S+ MTL GDLI TGTP GV L+PG V E++ Sbjct: 232 PTLLEHLSACMTLEVGDLIFTGTPAGVSA-------LEPGMVTRVELD 272 >UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Ascomycota|Rep: 2-keto-4-pentenoate hydratase - Sclerotinia sclerotiorum 1980 Length = 241 Score = 110 bits (264), Expect = 5e-23 Identities = 72/224 (32%), Positives = 120/224 (53%), Gaps = 12/224 (5%) Query: 71 APIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVD- 129 +P K++CIG NY DH E N + P P F K S+I+ P+ IR K VD Sbjct: 13 SPFKSASKVVCIGRNYADHITELNNSKPKQPFFFLKPPSSILPPNGGAVIRP---KGVDL 69 Query: 130 -WEVELCVVVGREASCVR---EEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSM 183 +EVEL +++G++ + E++A + Y ++ D++AR+ Q E K G + + K Sbjct: 70 HYEVELALIMGKQLKNLEPENEKEAYDSIESYAMSIDMTARNAQNEAKKKGLPWDIAKGF 129 Query: 184 DTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVP 243 DTF P+ +++ ++ V ++N +Q ST +++ IP +L IS VMTL Sbjct: 130 DTFLPMSN-IISKSQIPDPHNATVWLTVNNEHRQKDSTELMLYRIPRILSDISKVMTLEK 188 Query: 244 GDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 GD++LTGTP GVG + P + ++ G + + G +V +E+ Sbjct: 189 GDIVLTGTPKGVGSVK-PGDVMRVGISVGGKELTEGKIEVAVEE 231 >UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=11; Bradyrhizobiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase - Rhodopseudomonas palustris Length = 233 Score = 109 bits (263), Expect = 6e-23 Identities = 70/229 (30%), Positives = 113/229 (49%), Gaps = 11/229 (4%) Query: 59 PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPV 118 P P +V T+ V +I C+G NY +H +E P F+K + ++ PD Sbjct: 10 PPPQPTLAVAGTSDRFPVRRIWCVGRNYLEHVREMGNDERQPPFFFAKHAD-MVTPDGAT 68 Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ--KEKNMGQ 176 +TK + EVEL V + + E AL HV GY V D++ RD Q K Sbjct: 69 IPYPPLTKDLHHEVELVVALKSGRLNIPVERALDHVWGYAVGIDLTRRDLQIASRKKEQP 128 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 + +GKS D P G + + E+G ++ S+NG +Q+ ++++ ++P ++ ++S Sbjct: 129 WEIGKSFDASAPCG-ALRPASEIGHPATGKIWLSVNGTERQTGDLSEMIWNVPEIIAKLS 187 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 + + L GD+I+TGTP GV L PGD + I+ IG +V I Sbjct: 188 AQVELAAGDIIMTGTPAGVAA-------LSPGDAIACGIDGIGTLNVTI 229 >UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP02096p - Drosophila melanogaster (Fruit fly) Length = 236 Score = 109 bits (263), Expect = 6e-23 Identities = 66/184 (35%), Positives = 104/184 (56%), Gaps = 4/184 (2%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+ + LNY D +N+ P P+VF K +S+ + QP+ + V KV +EVEL VV Sbjct: 33 KIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEGQPI-VLPKVFTKVAYEVELGVV 91 Query: 138 VGREASCVREEDALQHVAGYTVAQDISAR-DWQKEKNMGQ-FLLGKSMDTFCPLGPCVLT 195 +G+ V + DA+ +VAGY +A D++A+ + + G + LGK DT P+ + Sbjct: 92 IGKPCKNVSKADAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFI-P 150 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 ++V L + ++NG LKQ+ TA L+ +P ++ +S MTL DLILTGTP G Sbjct: 151 IEKVTDPHNLPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGA 210 Query: 256 GMYR 259 ++ Sbjct: 211 DAFK 214 >UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Burkholderia phytofirmans PsJN|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia phytofirmans PsJN Length = 346 Score = 109 bits (261), Expect = 1e-22 Identities = 61/181 (33%), Positives = 98/181 (54%), Gaps = 5/181 (2%) Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160 P F + +S I PD + + T+++DWE+EL +V+GR V EDA VA + Sbjct: 151 PYFFQRPNSCIAPPDGEIHAESG-TEELDWELELGIVIGRRGRHVAREDAPNFVAACLIL 209 Query: 161 QDISARD--WQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQS 218 D++ R ++++ +L GK M P GP ++ + +G LR+ S+NG + Q Sbjct: 210 NDVTDRALIYRQDFPGADWLRGKGMPASMPAGPYLVPASVIGEIDALRLRLSVNGEVMQD 269 Query: 219 SSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278 ++ +P L+ +SS + L PGD+I TGTP G G R +LQ GDV+ +EI+ + Sbjct: 270 ELAGDMILDVPRLIEYLSSRVELRPGDVIATGTPAGTGAER--GRFLQDGDVIRAEIDGL 327 Query: 279 G 279 G Sbjct: 328 G 328 >UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=6; Burkholderia|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia multivorans ATCC 17616 Length = 426 Score = 108 bits (259), Expect = 2e-22 Identities = 71/214 (33%), Positives = 110/214 (51%), Gaps = 10/214 (4%) Query: 51 VKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVP--MVFSKFS 108 V++L TIP + V P+ + +C G NY+ H E + P M+F+K Sbjct: 151 VERLAMIDGPTIPEADVQWLPPVTANQQFVCQGANYRRHMIESGMDPDAKQFNMIFTKAP 210 Query: 109 STIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASC---VREEDALQHVAGYTVAQDISA 165 S I+ D V ++ + +D+E+EL +V+ R+ + V + + ++VAG + D SA Sbjct: 211 SCIVAADSRV-VKPRHVRFLDYEIELGLVLKRDITRHQPVTDANLHEYVAGIAIVNDYSA 269 Query: 166 RDWQKEKNMGQFLLGKSMDTFCPLGP--CVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQ 223 RD Q + QF GKS TF P+GP C+L + L ++ S+NG ++Q STA Sbjct: 270 RDVQIPQM--QFYKGKSFRTFGPVGPYLCLLERHDFPKLKTLELTLSVNGTVRQQDSTAN 327 Query: 224 LVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 LV+ L +S V L GDL+ TGTP G + Sbjct: 328 LVYGPAETLTELSGVHDLGAGDLLATGTPAGCAL 361 >UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=4; Actinomycetales|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Mycobacterium avium (strain 104) Length = 313 Score = 108 bits (259), Expect = 2e-22 Identities = 66/212 (31%), Positives = 112/212 (52%), Gaps = 11/212 (5%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVF-SKFSSTIIGPDQPVRI 120 +P+ + L +P+ +++ N+ H ++ + P +P+ F K S +I GP + + Sbjct: 50 VPVEGLNLLSPVTAPCRVVAQMTNFASHVKDAGMDPNTIPLTFFRKASGSITGPFDDI-V 108 Query: 121 RTDVTKKVDWEVELCVVVGRE---ASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF 177 + D + +D+EVE+ +V+GRE + V E + + AG V D+SARD Q K QF Sbjct: 109 KPDHVRFLDYEVEIGLVIGRELPVGAAVSEANLADYTAGAVVTNDVSARDIQLPKT--QF 166 Query: 178 LLGKSMDTFCPLGPC--VLTSDEVGAAVELRVSCSLNGVLKQSSST-AQLVHSIPSLLHR 234 KS TF P+GP +L +DE+ +LR+ +NG ++Q +++ L Sbjct: 167 YESKSYPTFTPVGPALVLLDADELKRFGDLRLQLRVNGQVRQDMRVDGDMIYPPVQALQA 226 Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQ 266 ++ L PGDL+LTGTP G + PP+ +Q Sbjct: 227 LARFQRLDPGDLVLTGTPVGTAL-SAPPKPVQ 257 >UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family protein; n=25; Enterobacteriaceae|Rep: Fumarylacetoacetate hydrolase family protein - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 218 Score = 107 bits (258), Expect = 2e-22 Identities = 64/183 (34%), Positives = 98/183 (53%), Gaps = 4/183 (2%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 V+K++C+G NY +H +E P P++F K + + QPV I ++ V EVEL Sbjct: 16 VNKVVCVGSNYSEHIKEMGSATPSEPVLFIKPETALCDLRQPVAIPKNLGS-VHHEVELA 74 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCV 193 V++G EE + +AGY VA D++ RD Q E K GQ + K+ D CP+ + Sbjct: 75 VLIGTPLKQANEERVARAIAGYGVALDLTLRDLQSEFKKAGQPWEKAKAFDGSCPISGFI 134 Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253 + E G + + +N ++Q +T ++ SI L+ +S TL GD+ILTGTP Sbjct: 135 PVA-EFGDPQQTELGVKVNDEVRQQGNTRDMITSILPLIAYMSRFFTLRAGDIILTGTPK 193 Query: 254 GVG 256 GVG Sbjct: 194 GVG 196 >UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG10641.1 - Gibberella zeae PH-1 Length = 230 Score = 107 bits (257), Expect = 3e-22 Identities = 64/173 (36%), Positives = 92/173 (53%), Gaps = 4/173 (2%) Query: 103 VFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQD 162 VFS S ++ P Q + D+E EL VV+GR A V +E+A+++V GYT A D Sbjct: 47 VFSGLS--VLKPGQKTGETAVIDDCGDYEAELAVVIGRAAKNVTKEEAMEYVLGYTAAND 104 Query: 163 ISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTA 222 IS+R Q ++ Q+ K D CPLGP +++ D V + + Q Sbjct: 105 ISSRTSQFGQS--QWCFSKGFDGSCPLGPALVSKDLVPDPSMFNIRGLKKDQVLQDCGAD 162 Query: 223 QLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275 L+ IP+L+ +S TL+PG +ILTGTP GVG+ RQP + GD + EI Sbjct: 163 DLIFDIPTLISFLSQGTTLLPGTVILTGTPAGVGVGRQPKVTISDGDEFSVEI 215 >UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 313 Score = 107 bits (256), Expect = 4e-22 Identities = 60/177 (33%), Positives = 98/177 (55%), Gaps = 5/177 (2%) Query: 98 PPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGY 157 P +P++F K ST+ GP + + I V ++ D+EVEL VV+GR+ V +A+ + GY Sbjct: 108 PVIPILFYKPISTLSGPGRDIVIPPCVAEQADYEVELVVVLGRDIKDVSPVEAMDAILGY 167 Query: 158 TVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDE---VGAAVELRVSCSLNGV 214 T++ D+SAR + + Q+ LGKS D + P+GPC++++ + + ++ LN Sbjct: 168 TLSNDVSAR--TRMFAVPQWGLGKSFDGWLPIGPCLVSASNPRGITNRDNIHLTTKLNNR 225 Query: 215 LKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVL 271 + Q +T+ ++ L +S TL G L++ GTP G G RQP L GD L Sbjct: 226 IMQDGNTSDMLWKTAETLAELSKGTTLEAGSLLIMGTPPGEGFKRQPKVCLNHGDTL 282 >UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 295 Score = 106 bits (254), Expect = 7e-22 Identities = 74/227 (32%), Positives = 110/227 (48%), Gaps = 11/227 (4%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 IP + AP KI+ + L Y+ +E PP P F K + + G VR Sbjct: 42 IPEAGARYLAPAEPT-KIIAVHLTYRSRVEEYGARVPPEPSYFLKPPTALNGHRGVVRWP 100 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 T+ +++E EL V+VGR V E+AL VAGYT A D+ D+ + + G L K Sbjct: 101 AG-TRFLNYEGELAVIVGRRMKGVGMEEALSCVAGYTCANDVGLHDF-RHADRGSMLRVK 158 Query: 182 SMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTL 241 D F PLGP V+ + + + LNG + Q L+ + L + ++TL Sbjct: 159 GQDGFLPLGPEVVPASRFDPE-DFALRTYLNGEVVQEGGAEDLLFGVAYQLADLCRLITL 217 Query: 242 VPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 288 PGD++LTGTP +P ++PGDV+ EIE IG +E++ Sbjct: 218 EPGDVVLTGTPAN----SRP---MRPGDVVEVEIEGIGRLSNTVEEW 257 >UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Fumarylacetoacetate (FAA) hydrolase - Halorubrum lacusprofundi ATCC 49239 Length = 273 Score = 105 bits (252), Expect = 1e-21 Identities = 68/227 (29%), Positives = 109/227 (48%), Gaps = 10/227 (4%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIR 121 +P + ++ AP+ K+ IGLNY +H + + P P F K SS + GP P+R+ Sbjct: 56 VPAADISFGAPLESFGKLWGIGLNYAEHAGDLDEQRPDEPASFMKPSSVLTGPSGPIRLP 115 Query: 122 TD-VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 + +++V E EL VV+GR V E VAG+ D++A D ++N Sbjct: 116 PESQSERVTAEAELAVVMGRTCRNVEEAAFEDVVAGFLPVIDMTAED-VLQRNPRFLTRS 174 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 KS DTF G + +E L V +NG ++ + ++ ++ S VMT Sbjct: 175 KSYDTFLVPGAALAVPEEPLDLDALSVQTEVNGEIEAENEIRNMLFPPSEIVSFHSDVMT 234 Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 L PGDL TGTPG +++PGD + + +E IG + + + Sbjct: 235 LEPGDLFSTGTPGAA--------HIEPGDEVRAVVESIGTVEAPVTR 273 >UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA) hydrolase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 349 Score = 104 bits (250), Expect = 2e-21 Identities = 65/183 (35%), Positives = 97/183 (53%), Gaps = 7/183 (3%) Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160 P +F + + GP V + + + DWE+E V+GR V E AL VAGYT+A Sbjct: 145 PYLFLGSPTALCGPYDDVVLPAEGDQH-DWELEFAAVIGRSGRHVPPERALDLVAGYTIA 203 Query: 161 QDISARD--WQKE-KNMG-QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216 DI+ RD ++ + K +G +L K+ TF P GP ++ + VG LR++ LNG Sbjct: 204 NDITTRDLVYRPDLKAIGTDWLRSKNAPTFLPTGPYIVPKEFVGDTSGLRITLRLNGETM 263 Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276 Q S + ++ + L+ SS + L PGDLILTG+P G G Y +L GDV+ + Sbjct: 264 QDESASDMIFDVARLVSYASSRVLLRPGDLILTGSPAGNGSYW--GRFLGEGDVMEGTVT 321 Query: 277 KIG 279 +G Sbjct: 322 GLG 324 >UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=3; Burkholderiales|Rep: 2-Keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 301 Score = 104 bits (250), Expect = 2e-21 Identities = 71/244 (29%), Positives = 118/244 (48%), Gaps = 20/244 (8%) Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDH------CQEQNLTPPPV-----PMVFSKFSS 109 T+ + + P+ I G NY+DH +LT P P F K Sbjct: 60 TMEPAQIRFLPPLSQPGVIYGAGANYRDHVVAMAKAVNMDLTTDPKADGVPPWHFIKAGR 119 Query: 110 TIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ 169 + + T+ +DWE EL VV+G+ + DAL VAGYT+A D+SARD Sbjct: 120 GTLSAHRQALPYPSHTRMLDWEAELAVVIGKACRNISPGDALDCVAGYTIANDLSARDNL 179 Query: 170 KEKNMG-------QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTA 222 + + + ++ K + CPLGP + + V + L + +N LKQ+S+T+ Sbjct: 180 RREQVDASSPFRFDWIGHKCFEGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTS 239 Query: 223 QLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 ++++ + +S +TL PGD++LTGTP GVGM + +L+ GD + I+ +G + Sbjct: 240 NHLYTVAEQIAYLSERLTLYPGDVLLTGTPAGVGM--ESGVFLKRGDSIRVWIDGLGELE 297 Query: 283 VRIE 286 ++ Sbjct: 298 TSLQ 301 >UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella pertussis|Rep: Putative hydrolase - Bordetella pertussis Length = 316 Score = 104 bits (249), Expect = 3e-21 Identities = 65/191 (34%), Positives = 103/191 (53%), Gaps = 7/191 (3%) Query: 100 VPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASC-VREEDALQHVAGYT 158 +P F K +S + D V V D+EVE+ V+G E AL+HV GYT Sbjct: 127 MPAGFIKIASVMTPHDSAVARPCGVLA-FDYEVEVAAVLGGPVPLGTPPERALEHVFGYT 185 Query: 159 VAQDISARDWQKEKNMGQFL-LGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQ 217 + D+SAR+W + + Q + +GK+ PLGP ++T+DEV +L +S S+NG +Q Sbjct: 186 LFNDLSAREWARAEMKNQMIAMGKNFPGAGPLGPWIVTADEVPDPAQLELSLSVNGEPRQ 245 Query: 218 SSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQP---PEYLQPGDVLTSE 274 S +++ + L+ S + L G+LI +GTP G + R+P P +L+PGD++ + Sbjct: 246 HGSCKEMIFTFAQLIAHWSRI-GLGAGELIASGTPEGGAISRKPDPAPFFLKPGDIVEAH 304 Query: 275 IEKIGAFDVRI 285 +IG RI Sbjct: 305 CPQIGTLRTRI 315 >UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Proteobacteria|Rep: Faa-hydrolase family protein - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 265 Score = 104 bits (249), Expect = 3e-21 Identities = 67/207 (32%), Positives = 101/207 (48%), Gaps = 10/207 (4%) Query: 56 STKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSSTI--I 112 S TIP+ P+ +I CIG NY H +E P P F K S I + Sbjct: 40 SVAQPTIPIVGSNEQFPVR---RIYCIGRNYAAHAREMGSDPTREPPFFFQKPSDAIQYV 96 Query: 113 GPDQPV-RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK- 170 P + V +TK +E+EL + + + E+ALQHV GY V D++ RD Q Sbjct: 97 APGKVVDHPYPTLTKNYHYEIELVAAINKGGKNISVENALQHVFGYAVGLDMTRRDLQAA 156 Query: 171 -EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIP 229 +K + +GKS D P+GP + +G E ++ +NG +KQS+ Q++ S+ Sbjct: 157 MKKEEKPWEIGKSFDMSAPIGPLHPVAS-IGNFTEGKIWLKVNGQVKQSADLKQMIWSVA 215 Query: 230 SLLHRISSVMTLVPGDLILTGTPGGVG 256 + +S L+PGD+I +GTP VG Sbjct: 216 EQISNLSKAFELMPGDIIYSGTPENVG 242 >UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=123; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 252 Score = 103 bits (248), Expect = 4e-21 Identities = 63/209 (30%), Positives = 100/209 (47%), Gaps = 10/209 (4%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 V ++ C+G NY DH +E P P F + I P +T + E+EL Sbjct: 45 VRRVFCVGRNYADHAREMGADPDREPPFFFTKPADAIVPASGTVAYPPLTNDLHHEIELV 104 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCV 193 V +G++ + DAL HV GY V D++ RD Q E K + + + K D P+ + Sbjct: 105 VAIGKDGRAIDPADALSHVWGYGVGIDLTRRDLQAEAKKLSRPWDWAKGFDASGPV-TAL 163 Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253 + G R+ ++NG +Q A ++ ++P ++ +S + L GDLI TGTP Sbjct: 164 RAASATGHPATGRIWLAVNGDTRQQGDLADMIWAVPDVIAYVSRSVELKAGDLIFTGTPA 223 Query: 254 GVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 GVG LQPGD +T ++ + F+ Sbjct: 224 GVGA-------LQPGDRVTGGVDGVATFE 245 >UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|Rep: Bll3146 protein - Bradyrhizobium japonicum Length = 262 Score = 103 bits (247), Expect = 5e-21 Identities = 66/202 (32%), Positives = 101/202 (50%), Gaps = 5/202 (2%) Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 T+ LS V L AP KI+ + N+ + N PP P+ K +++I P +R Sbjct: 45 TLALSEVELLAPC-APSKIVALWNNFHALAAKLNQPEPPEPLYLLKATTSIAAPGAVIRR 103 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARD-WQKEKNMGQFLL 179 + K +E EL +V+GR + V +A + GYT DI+A D + Q+ Sbjct: 104 PSYYDGKTTYEGELGIVIGRTCARVSPGEADSFIFGYTCVNDITANDILTSDPTFPQWAR 163 Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239 K +D + P GP + T + +L V LNG +Q+ + ++ S L+ RIS M Sbjct: 164 AKGIDDYGPFGPVIATGLD---PAKLVVRTILNGAERQNYPISDMIFSAQELVSRISHDM 220 Query: 240 TLVPGDLILTGTPGGVGMYRQP 261 TL+PGDLI GT GVG+ ++P Sbjct: 221 TLLPGDLIAVGTSVGVGVMKEP 242 >UniRef50_Q72P81 Cluster: Fumarylacetoacetate hydrolase family protein; n=2; Leptospira interrogans|Rep: Fumarylacetoacetate hydrolase family protein - Leptospira interrogans serogroup Icterohaemorrhagiae serovarcopenhageni Length = 316 Score = 103 bits (247), Expect = 5e-21 Identities = 82/270 (30%), Positives = 132/270 (48%), Gaps = 22/270 (8%) Query: 4 VQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIP 63 ++F K+S I+ G +E D I+ ++ D S L+ L+ KK K K IP Sbjct: 6 IRFKKKNS---IQWGKIEEDKILTLDCGDLSTKD-FLEFLK-------KKKKYPKQKLIP 54 Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTP--PPVPMVFSKFSSTIIGPDQPVRIR 121 + V++ +PI +I+C G NY+ H E L P + F+K +++ P V IR Sbjct: 55 IQEVSVLSPITSPCQIICQGANYRQHQIESGLDPDDKTYNLFFTKSDASLSPPIGKV-IR 113 Query: 122 TDVTKKVDWEVELCVVVGREASC---VREEDALQHVAGYTVAQDISARDWQKEKNMGQFL 178 K +D+E+EL V G+ + + +++A + +A DISARD Q + Q+ Sbjct: 114 PSHVKLLDYEIELGFVFGKSFDSTLKLNSKSIREYIAAFFMANDISARDVQLPQM--QWY 171 Query: 179 LGKSMDTFCPLGP--CVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 GKS TFCP GP VL + L ++ +N ++Q S + LV + +S Sbjct: 172 KGKSYRTFCPTGPYLSVLDPGDFDLLDSLELTLLVNSQIRQKDSASNLVFKPLESVLELS 231 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQ 266 + GD++LTGTP G + R P + +Q Sbjct: 232 QFCNISTGDVLLTGTPSGCAL-RAPGKLIQ 260 >UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Novosphingobium aromaticivorans (strain DSM 12444) Length = 296 Score = 103 bits (247), Expect = 5e-21 Identities = 62/202 (30%), Positives = 107/202 (52%), Gaps = 12/202 (5%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+C+ LNY QE PP P F K T + + +R + K +++E E+ +V Sbjct: 47 KIICVHLNYHSRVQEFITKLPPAPTYFQK-PLTALNTHKGAIVRPERCKWLNYEGEIAIV 105 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSD 197 +G+ + +A ++ GY+VA D D+ ++ + G L K DT CP+GP ++T Sbjct: 106 IGKTCRNISPAEAGDYILGYSVANDYGLHDF-RDTDAGSMLRVKGSDTLCPIGPGLVTGW 164 Query: 198 EVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGM 257 + + + +NGVLKQ +T+ + + L+ I+ +TL PGD++L+GTP Sbjct: 165 DFR---DKMIRTYVNGVLKQEDNTSNMEWDMHYLVADIARTITLEPGDVLLSGTPAN--- 218 Query: 258 YRQPPEYLQPGDVLTSEIEKIG 279 +P +Q GDV+ E++ +G Sbjct: 219 -SRP---VQIGDVVEVEVDGLG 236 >UniRef50_A4CE53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Pseudoalteromonas tunicata D2|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Pseudoalteromonas tunicata D2 Length = 221 Score = 103 bits (247), Expect = 5e-21 Identities = 62/181 (34%), Positives = 97/181 (53%), Gaps = 4/181 (2%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 K +CIG NY++H E N P PM+F K SS+ + + + + + +E EL ++ Sbjct: 18 KAVCIGRNYREHAAELNNAVPDSPMLFIKPSSSFVAFKGQIPLAQRLGEH-HYEAELALL 76 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCVLT 195 +G+ S E D Q V G VA D++ R+ Q E K+ G + K+ D C + P + Sbjct: 77 IGQTISASTELDLQQQVIGIGVAMDLTLRNVQAELKSKGHPWEKAKAYDNSCIVSPFIQI 136 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 +++ L + S+N ++Q T+++V SI LL I TL PGD++LTGTP GV Sbjct: 137 TEQTDFN-NLEFNLSINNEIRQIGHTSEMVFSIVQLLDEIRQYFTLQPGDIVLTGTPKGV 195 Query: 256 G 256 G Sbjct: 196 G 196 >UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep: ENSANGP00000019097 - Anopheles gambiae str. PEST Length = 232 Score = 103 bits (247), Expect = 5e-21 Identities = 67/203 (33%), Positives = 103/203 (50%), Gaps = 8/203 (3%) Query: 63 PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSK---FSSTIIGPDQPVR 119 P T + + KI+ G+NYK+ + N P P++F K S+ G +R Sbjct: 9 PSKMPTTSKFLQSTRKIIGAGVNYKEILRLTNSPKPDAPVIFFKPISGSTGSTGTPPTIR 68 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDW---QKEKNMGQ 176 I +++E EL V++GR + V + A+ +V GY +A D++ D+ + K + Sbjct: 69 IPRVFGGVINFEAELGVIIGRRCANVPTDQAMAYVGGYCLALDMTGMDFILDARPKGL-P 127 Query: 177 FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 + LGK DT P+ V +D + ++RV C +NGV KQ ST L+ I L+ +S Sbjct: 128 WCLGKGFDTSTPVSALVQRAD-LPNPDDVRVWCEVNGVRKQDDSTRNLIFPIAELIAYVS 186 Query: 237 SVMTLVPGDLILTGTPGGVGMYR 259 MTL DL+LTGTP G G R Sbjct: 187 RFMTLEENDLLLTGTPAGAGPVR 209 >UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Marinomonas sp. MWYL1|Rep: Fumarylacetoacetate (FAA) hydrolase - Marinomonas sp. MWYL1 Length = 235 Score = 102 bits (245), Expect = 9e-21 Identities = 62/191 (32%), Positives = 103/191 (53%), Gaps = 7/191 (3%) Query: 73 IHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSSTII--GPDQPVRIRTDV-TKKV 128 ++ V ++ C+G NY +H +E P P F+K SS ++ G + I + T + Sbjct: 21 VYPVGRVYCVGRNYAEHSKEMGDDPERDPPFFFAKDSSCVVPAGFSESTLITYPMATSQF 80 Query: 129 DWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTF 186 ++EVEL + +G+ + + + + + GY V D++ RD Q + K G+ + +GKS D Sbjct: 81 EYEVELVIAIGKGGRNLTLQQSREAILGYAVGLDMTRRDLQSQAKKKGRPWEVGKSFDES 140 Query: 187 CPLGPCVLTSDEVGAAV-ELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245 P+ P +L +D + V + + +NG LKQ S L SI ++ ++S V L PGD Sbjct: 141 APISPILLKTDLLADNVSKAEIGLKVNGDLKQISHVTNLTWSIEEVICKLSEVFELRPGD 200 Query: 246 LILTGTPGGVG 256 LI+TGTP VG Sbjct: 201 LIMTGTPENVG 211 >UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; Vibrio splendidus 12B01|Rep: Putative uncharacterized protein - Vibrio splendidus 12B01 Length = 274 Score = 101 bits (243), Expect = 2e-20 Identities = 63/193 (32%), Positives = 101/193 (52%), Gaps = 10/193 (5%) Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 +IPL SV + P +K+ +G+N+ H PPP+ F K S++I + +++ Sbjct: 65 SIPLESVEVLLPTKP-EKVFAVGMNFASHLASPADAPPPM---FLKLPSSLILTGEVIQV 120 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 + V +E EL VV+GRE S EE+A Q + G TV DI+ R WQ Q+L Sbjct: 121 PPKA-RNVHFEGELVVVIGRELSQASEEEAEQAIFGVTVGNDITERSWQGADL--QWLRA 177 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 K+ D F P+G ++ + + ++ +NG + Q +T+ ++H ++ +S T Sbjct: 178 KASDGFGPVGNTIVRGIDYN---NIELTTRVNGKVVQQENTSFMIHKPRKVVSYLSYYFT 234 Query: 241 LVPGDLILTGTPG 253 L PGDLI GTPG Sbjct: 235 LKPGDLIFMGTPG 247 >UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Jannaschia sp. (strain CCS1) Length = 305 Score = 100 bits (240), Expect = 4e-20 Identities = 84/291 (28%), Positives = 133/291 (45%), Gaps = 22/291 (7%) Query: 17 VGYLEGDDIVDINKA---DSSLPTTLLQILRN-GDLEKVKKLKSTKP--ATIPLSSVTLT 70 V L+ D ++D+ +A D T+ I L+K + + P A I LS Sbjct: 15 VARLDDDQVLDLLEASGGDVHFVNTVAMIEAGPAALDKARAVLEDPPTRAVIALSQAEHR 74 Query: 71 APIHGVDKILCI--------GLNYKDHCQEQNLTPPPV----PMVFSKFSSTIIGPDQPV 118 P+ V C+ G + + PPV P+ + + IG Q V Sbjct: 75 VPLRPVQYRDCLVFEQHLINGFKQAEKMTGRPFAIPPVWYEQPIYYKGNRMSFIGHGQTV 134 Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF- 177 R + +D E+EL +++G+E + + E A +H+ GYT+ D+SARD Q + GQ Sbjct: 135 RWPA-YSDYLDLELELAIIIGKEGADIPRETAHEHIWGYTILNDVSARDAQMREMAGQLG 193 Query: 178 -LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRIS 236 GK DT LGP ++T+DEV L + S+NG ++A + ++ IS Sbjct: 194 PAKGKDFDTGNILGPWIVTADEVSHPAVLNMDVSVNGERWGGGTSADMQFDFAQIIAHIS 253 Query: 237 SVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 + L PG++I +GT G G + + L GD++ IEKIG I+K Sbjct: 254 ASERLFPGEVIGSGTV-GTGCGLEIGKRLSDGDMMDLTIEKIGTLTNTIKK 303 >UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Arthrobacter|Rep: Fumarylacetoacetate (FAA) hydrolase - Arthrobacter sp. (strain FB24) Length = 277 Score = 100 bits (240), Expect = 4e-20 Identities = 61/179 (34%), Positives = 97/179 (54%), Gaps = 13/179 (7%) Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVA 160 P F K +++++GP + + V VD E EL +V+GR+A + E+A V G+T+ Sbjct: 102 PQAFHKAATSVVGPGDAIELAPGVGH-VDPEAELTIVIGRKARGLTLENARGAVLGFTIG 160 Query: 161 QDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSS 220 D++AR+ QK + ++ KS DTF P GP ++T + A L + NG +++S Sbjct: 161 NDVTARELQKSDEL--WISAKSQDTFTPAGPWIVTGLDTAA---LSIGIVHNGSELRAAS 215 Query: 221 TAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 +A L + +L ++S MTL PGDL+LTG P L PGD +T ++ IG Sbjct: 216 SADLGWKVDEILVYLTSFMTLHPGDLVLTGFPA-------ESARLHPGDTVTCRVQGIG 267 >UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep: Isomerase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 224 Score = 100 bits (239), Expect = 5e-20 Identities = 64/181 (35%), Positives = 95/181 (52%), Gaps = 4/181 (2%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 KI+ +GLNY H +E P P+VF K +S+ + + I + + EVEL VV Sbjct: 15 KIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIPHPLDS-LHHEVELAVV 73 Query: 138 VGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF--LLGKSMDTFCPLGPCVLT 195 +G++A V E A+ ++ GY +A D++AR+ Q L K DTF P+ VL Sbjct: 74 IGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLAKGQDTFTPISS-VLP 132 Query: 196 SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGV 255 V L + ++ +Q T ++ +P L+ ISSVMTL GD+ILTGTP G+ Sbjct: 133 KAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFKGDVILTGTPEGI 192 Query: 256 G 256 G Sbjct: 193 G 193 >UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep: Putative hydrolase - Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 /FAM18) Length = 218 Score = 99 bits (238), Expect = 6e-20 Identities = 67/196 (34%), Positives = 102/196 (52%), Gaps = 5/196 (2%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123 ++SV L V I CIG NY H +E P P+VF K S +I+ + + + Sbjct: 1 MASVFLEGEAVEVGNIFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILL-PE 59 Query: 124 VTKKVDWEVELCVVVGREASCVRE-EDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLG 180 ++ V +E EL ++VG+++ + E ED L VAGY V D++ARD Q K G +L Sbjct: 60 FSRDVQFECELVLLVGKDSDGMGEGEDILGCVAGYGVGLDLTARDIQCHLKAQGLPWLKA 119 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 K + +D +G ++ S NGVLKQ T +++ I +LH++++ Sbjct: 120 KGFRHSACVSDFA-AADRIGNPEKVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYG 178 Query: 241 LVPGDLILTGTPGGVG 256 L GDL+ TGTP GVG Sbjct: 179 LGKGDLVFTGTPSGVG 194 >UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=1; Schizosaccharomyces pombe|Rep: Uncharacterized hydrolase C21C3.09c - Schizosaccharomyces pombe (Fission yeast) Length = 221 Score = 99.5 bits (237), Expect = 9e-20 Identities = 76/221 (34%), Positives = 114/221 (51%), Gaps = 19/221 (8%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP-VRIRTDVTKKVDWEVELCV 136 K++CIG NY H +E N P P F K +S I+ P + I DV+ +EVEL + Sbjct: 7 KVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVS--AHYEVELGL 64 Query: 137 VVGREASCVREEDA---LQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLGP 191 ++ R + L + Y V D++AR+ Q E K G + K DTF P+GP Sbjct: 65 IMKDRLPARRPVSSNSWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVGP 124 Query: 192 CV---LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLIL 248 + L D +EL SLNG + Q ST+ +++ IP + I+ M+L PGDL+L Sbjct: 125 IIPKHLIPDPHNVILEL----SLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNPGDLVL 180 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKI--GAFDVRIEK 287 TGTP GVG P + +LT++ ++I F+++ EK Sbjct: 181 TGTPKGVGPV--VPGDILSARLLTAQEQEIIPSKFEIKAEK 219 >UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7; Saccharomycetales|Rep: Uncharacterized hydrolase YNL168C - Saccharomyces cerevisiae (Baker's yeast) Length = 259 Score = 99.1 bits (236), Expect = 1e-19 Identities = 76/230 (33%), Positives = 115/230 (50%), Gaps = 39/230 (16%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRT-------------DV 124 KI+CIG NY H +E N + P P F K +S+I+ P ++T D Sbjct: 11 KIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDG 70 Query: 125 TK----------KVDWEVELCVVVGREASCV---REEDALQHVAGYTVAQDISARDWQKE 171 T KV E+EL ++V + S V + E+ ++G +A D++AR+ Q E Sbjct: 71 TNPGPIFIPRGVKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDE 130 Query: 172 -KNMG-QFLLGKSMDTFCPLGPCV----LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLV 225 K G + + K DTF P+ V +S + RV CS+NG L+Q T ++ Sbjct: 131 AKKKGLPWTISKGFDTFMPISAIVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNLML 190 Query: 226 HSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275 H + +L IS++++L PGD+ILTGTP GVG L+PGD + E+ Sbjct: 191 HPLHKILQHISTMISLEPGDIILTGTPAGVG-------ELKPGDRVHCEL 233 >UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase; n=8; Pseudomonas|Rep: 4-hydroxyphenylacetate degradation; 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase - Pseudomonas entomophila (strain L48) Length = 224 Score = 98.7 bits (235), Expect = 1e-19 Identities = 66/183 (36%), Positives = 98/183 (53%), Gaps = 11/183 (6%) Query: 97 PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAG 156 PP P++F K +T Q V V K++ L VV+GR+AS V E+AL+HVAG Sbjct: 39 PPVKPVLFIKTPNTRNSHGQAVTYPAAV-KRLQPGPALGVVMGRDASRVSAENALEHVAG 97 Query: 157 YTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216 YT+ + S + + + K D FCPLGP ++ + +V L + +NG L+ Sbjct: 98 YTIVNEFSLPE---DSYYRPAVKAKCRDGFCPLGPQLVPAAQVANPDALGIRLWVNGELR 154 Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIE 276 Q ++TA V S+ L+ IS MTL GD+++TGTP G + PGD +T EI+ Sbjct: 155 QHNNTANCVRSVAQLIAEISEFMTLHAGDVLITGTPEG-------RIDVLPGDRVTVEID 207 Query: 277 KIG 279 +G Sbjct: 208 GLG 210 >UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Moritella sp. PE36|Rep: Fumarylacetoacetate hydrolase family protein - Moritella sp. PE36 Length = 231 Score = 97.9 bits (233), Expect = 3e-19 Identities = 59/184 (32%), Positives = 101/184 (54%), Gaps = 4/184 (2%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 V K++CIG NY DH +E P ++F K S++++ D+P+ + D+ + + E+E+ Sbjct: 28 VGKVVCIGRNYLDHIRELGNDVPEQALLFIKPSTSLVALDKPLPLPVDLGECHN-ELEVA 86 Query: 136 VVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPLGPCV 193 +++ + + + G + D++ RD Q K G + K+ D CP+ P + Sbjct: 87 LLIKSPITKGTSIVLSELIWGVGLGLDLTLRDLQSSLKGQGHPWERAKAFDNACPVTPFI 146 Query: 194 LTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPG 253 + E G L + S+N L+Q TA ++ SI SLL I++ TL+PGD++LTGTP Sbjct: 147 PLA-EFGDVNNLDFTLSVNDQLRQQGCTANMMRSIESLLTEITACFTLLPGDIVLTGTPA 205 Query: 254 GVGM 257 GVG+ Sbjct: 206 GVGV 209 >UniRef50_A2CBF2 Cluster: Putative uncharacterized protein; n=1; Prochlorococcus marinus str. MIT 9303|Rep: Putative uncharacterized protein - Prochlorococcus marinus (strain MIT 9303) Length = 237 Score = 97.5 bits (232), Expect = 3e-19 Identities = 62/192 (32%), Positives = 104/192 (54%), Gaps = 10/192 (5%) Query: 101 PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREED-ALQHVAGYTV 159 P++ SK +S+I G V + +++DWE EL V +G+E + +D A + + + V Sbjct: 50 PILSSKATSSI-GTSNSVIPFSVQNREIDWEAELVVEIGKECFALESKDEAHKVIMRWGV 108 Query: 160 AQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAA----VELRVSCSLNGVL 215 DI+ R WQ+ ++ GQ++ GKS F PL + SD AA ++ + C +NG L Sbjct: 109 GNDITDRWWQR-RDGGQWIRGKSFPGFAPL---IFNSDSFSAARNNELDREIRCIVNGKL 164 Query: 216 KQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275 Q ++++ S ++ +IS + L+ GDLI GT G + P YL+ GD +T+EI Sbjct: 165 VQHGVLSEMISSPVQIVWQISQCLQLLKGDLIFCGTFPGSALNSNPSTYLEIGDEVTTEI 224 Query: 276 EKIGAFDVRIEK 287 E +G ++ K Sbjct: 225 EGLGKLHNKVVK 236 >UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 255 Score = 96.7 bits (230), Expect = 6e-19 Identities = 58/183 (31%), Positives = 100/183 (54%), Gaps = 5/183 (2%) Query: 93 QNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKV-DWEVELCVVVGREASCVREEDAL 151 Q LT P P +++K ++++ P++ + I + + D+E EL V E V E A Sbjct: 57 QKLTIPSNPPLWTKPAASLAHPNEEIPINDFCARSLPDYEGELVFVTSEECKDVTESQAK 116 Query: 152 QHVAGYTVAQDISARDWQKEKNM-GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELR-VSC 209 ++ GYT+ D++ R +Q NM GQF K+ D F P+ P VL S ++ +V+ ++ Sbjct: 117 DYILGYTIGNDLTCRMFQLPGNMSGQFFFAKAFDHFAPIDP-VLISPKLFESVKRNGLTL 175 Query: 210 SLNGVLKQSSSTAQ-LVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPG 268 +NG ++Q + ++ S +L +S T+ G ++TGT GVG +R+P +LQ G Sbjct: 176 KVNGEVRQKADLHNDMIFSPERILSHMSQGTTIPAGTAVMTGTCEGVGAFRKPKVFLQQG 235 Query: 269 DVL 271 DV+ Sbjct: 236 DVV 238 >UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA) hydrolase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 320 Score = 95.5 bits (227), Expect = 1e-18 Identities = 80/292 (27%), Positives = 138/292 (47%), Gaps = 31/292 (10%) Query: 16 RVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHG 75 R+G + G++I + + T +L +L D E+ ++ T A++PL+ V L AP+ Sbjct: 13 RLGVVSGEEIGPLPEG-----TDVLDLLA-ADPEERDRIARTAEASVPLTGVRLLAPLQ- 65 Query: 76 VDKILCIGLNYKDHCQ-------EQNLTPPP---VPMVFSKFSSTIIGPDQPVRIRTDVT 125 L + +++H + E+ P +P + ++IGP PV + Sbjct: 66 -PPTLRDFVVFEEHVEGITRSVSEEGGVPEAWYEIPTFYFGNPYSVIGPQDPVAVPPGC- 123 Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDT 185 + +D+E+E+ ++GR S + E+A H+AGYT+ D SARD Q+ + K D Sbjct: 124 EALDFELEVAAIIGRAGSNLAPEEARGHIAGYTILNDWSARDLQRHEMQIGLGPAKGKDF 183 Query: 186 FCPLGPCVLTSDEV-----GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 LGP ++TSDE+ + L + +NG + A + S L+ S Sbjct: 184 ANTLGPWIVTSDELEPYRRDGRLHLEMEVFVNGEKLGDDTLANMAWSFEELVAYASRGTW 243 Query: 241 LVPGDLILTGTPGGVGMY-------RQPPEYLQPGDVLTSEIEKIGAFDVRI 285 + PGD++ +GT G + RQ P L+PGDV+ +E IG + R+ Sbjct: 244 VRPGDVLGSGTCGSGCLAELWGRVGRQEPPLLEPGDVVRMTVEGIGTIENRV 295 >UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep: PlaH - Streptomyces sp. Tu6071 Length = 294 Score = 95.1 bits (226), Expect = 2e-18 Identities = 73/199 (36%), Positives = 99/199 (49%), Gaps = 10/199 (5%) Query: 63 PLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFS---KFSSTIIGPDQPVR 119 PLS VTL P KI C+ LNY P P S K ST++G V Sbjct: 47 PLSEVTLLPPAEPT-KIACVALNYAPQGSPTGPGRPANPAACSVVLKPPSTLVGHGAVVG 105 Query: 120 IRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISA--RDWQKEKNMGQF 177 ++ E EL VV+G V E A + VAGYT A D++A R +E + Sbjct: 106 -HPGEPWELRHEAELAVVIGTACKGVPAERAAEVVAGYTCADDLTAYVRRAPEEPSGHPP 164 Query: 178 LLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISS 237 + K DTF PLGP LT+D A V ++C +NG ++Q T L+ + ++ +S Sbjct: 165 VWAKHFDTFTPLGPW-LTTDLDPADVP--ITCRVNGEVRQDGGTRGLLTPVHEIVAVVSR 221 Query: 238 VMTLVPGDLILTGTPGGVG 256 M+L+PGD+ILTGTP G G Sbjct: 222 HMSLLPGDVILTGTPTGSG 240 >UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium japonicum|Rep: Blr7583 protein - Bradyrhizobium japonicum Length = 261 Score = 94.3 bits (224), Expect = 3e-18 Identities = 69/225 (30%), Positives = 110/225 (48%), Gaps = 19/225 (8%) Query: 61 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQE----QNLTP--PPVPMVFSKFSSTIIGP 114 T+PL V + P+ C+GLNY H +E + P P P + + + +I Sbjct: 39 TLPLGEVKIELPLIP-RTFYCVGLNYLKHLKEAADKRGEVPAVPDRPEIGYRAQNALIAH 97 Query: 115 DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNM 174 D+ V I + T K+ +E EL VV+G++ + +++A+ V GYT+ D+S R WQK Sbjct: 98 DEEVVIPSFATDKIHYEGELVVVIGKKVKHLTKQNAMDCVFGYTIGNDVSERSWQKADR- 156 Query: 175 GQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234 K+ DTF P+GP + T + A +E V +NG T ++ + L Sbjct: 157 -SLWRSKNADTFKPMGPWIETEANL-ARMETVV--RVNGKETNRFYTNDMIFGVVPFLVE 212 Query: 235 ISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIG 279 ++ TL PGD+I GT G P+ ++ GDV+ +I IG Sbjct: 213 LTKYFTLWPGDVIWMGTDGA------SPD-IKHGDVVEIDITGIG 250 >UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Alcanivorax borkumensis SK2|Rep: Fumarylacetoacetate hydrolase family protein - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 233 Score = 94.3 bits (224), Expect = 3e-18 Identities = 59/187 (31%), Positives = 96/187 (51%), Gaps = 11/187 (5%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELC 135 V K++C+G NY DH +E P P++F K ++ + +P+ + + V EVE+ Sbjct: 29 VGKVVCVGRNYADHAKELGNETPDAPILFMKPATALTSLHEPL-VLPEGQGPVHHEVEMV 87 Query: 136 VVVGREASCVREEDALQHV----AGYTVAQDISARDWQKE-KNMGQ-FLLGKSMDTFCPL 189 V++G+ +R+E L HV A Y + D++ R+ Q + K G + K+ D P+ Sbjct: 88 VLIGKR---IRKETRLDHVRFSVAAYGIGLDLTLREVQNQLKEKGHPWERAKAFDGAAPV 144 Query: 190 GPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILT 249 + + + +L V+ LN +KQ T Q++ LL IS TL PGD++ T Sbjct: 145 SGFI-DARGISVRQDLGVTLELNDAVKQHGHTGQMLFPTFELLSEISQTFTLEPGDVVFT 203 Query: 250 GTPGGVG 256 GTP GVG Sbjct: 204 GTPAGVG 210 >UniRef50_A0QS23 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 206 Score = 93.9 bits (223), Expect = 4e-18 Identities = 60/184 (32%), Positives = 92/184 (50%), Gaps = 3/184 (1%) Query: 97 PPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREA-SCVREEDALQHVA 155 PP VP +F K + ++IGP +P+++ V +V E EL +V+G + V E A +A Sbjct: 18 PPDVPQLFVKNTHSVIGPGEPLQLTGSVATRVVAEGELAIVIGDQCRDLVTAEQARTVIA 77 Query: 156 GYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVL 215 GY VA D++ARD Q+ + + GK +D FCPLG ++ ++ ++ + ++ L Sbjct: 78 GYWVANDVTARDLQEVDD--HWSRGKGLDGFCPLGVEMVAPRDMPTWKDVMIRTWVDDEL 135 Query: 216 KQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEI 275 Q S A L+ S TL PGD+ L GTP + L+PG EI Sbjct: 136 VQDESVAAAYVGPEELVCWASQQFTLHPGDIFLLGTPAYRPAGDESRAVLKPGHTARVEI 195 Query: 276 EKIG 279 IG Sbjct: 196 TGIG 199 >UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Alphaproteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 265 Score = 93.5 bits (222), Expect = 6e-18 Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 20/230 (8%) Query: 62 IPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSSTII--GPDQPV 118 +P +V A ++ V ++ C+G NY H +E P P F+K + ++ G D P Sbjct: 46 LPAVAVKGEAALYPVRRVFCVGRNYAGHAREMGGDPNREAPFYFTKPADALVPGGGDIPY 105 Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQ- 176 T + E+EL V + R ++A + GY V D++ RD Q ++ G+ Sbjct: 106 ---PPGTANLHHEIELVVALSRSVYKCTPDEASTAIFGYAVGLDMTRRDLQFAARDKGRP 162 Query: 177 FLLGKSMDTFCPLGPCVLT-SDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235 + LGK+ + P+ P V + ++ ++ L V NG ++QS +++ S+P ++ + Sbjct: 163 WCLGKAFEFSAPISPLVRADAPKLAGSITLEV----NGQIRQSGDLNEMIWSVPEVIAHL 218 Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 S L GDLI TGTP GVG + GDVL IE +G +V I Sbjct: 219 SQYYHLGAGDLIFTGTPEGVGP-------VVAGDVLRGAIEGVGELEVHI 261 >UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=8; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Silicibacter sp. (strain TM1040) Length = 256 Score = 93.1 bits (221), Expect = 7e-18 Identities = 65/202 (32%), Positives = 100/202 (49%), Gaps = 10/202 (4%) Query: 58 KPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP 117 +PA +P++ T P+ ++ CIG NY H E P P F F T D Sbjct: 39 QPA-LPIAESTALFPVR---RVYCIGRNYAAHAVEMGHDPDREPPFF--FQKTPDSLDAS 92 Query: 118 VRIRTDV-TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-EKNMG 175 R V ++ V E EL V +G+ + E+ AL HV GY +A D++ RD Q K G Sbjct: 93 GRFPYPVMSEDVHHEAELLVALGKGGENISEDAALDHVWGYGLALDMTRRDLQGIAKKAG 152 Query: 176 Q-FLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHR 234 + + +GKS + P+ P + + +G ++ ++NG +Q Q++ IP ++ Sbjct: 153 RPWEIGKSFEHAAPVAP-LTPATTIGHPDAGVMTLTVNGTPRQQGDLNQMIWKIPEMIAH 211 Query: 235 ISSVMTLVPGDLILTGTPGGVG 256 +S L GD+ILTGTP GVG Sbjct: 212 LSQYYRLAAGDVILTGTPAGVG 233 >UniRef50_A4F0I3 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Roseobacter sp. SK209-2-6|Rep: Fumarylacetoacetate hydrolase family protein - Roseobacter sp. SK209-2-6 Length = 231 Score = 93.1 bits (221), Expect = 7e-18 Identities = 63/197 (31%), Positives = 96/197 (48%), Gaps = 11/197 (5%) Query: 69 LTAPIHG------VDKILCIGLNYKDHCQEQNL-TPPPVPMVFSKFSSTIIGPDQPVRIR 121 LT P+HG V++I C+G NY H E + P F+K ++ + V Sbjct: 12 LTIPVHGETAEFPVNRIFCVGRNYAAHAAEMGVEVDREAPFYFTKSAANAVLTGCEVPYP 71 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQ--FLL 179 T+ +E+EL + +G A E+A + GY A D++ RD Q + Q + L Sbjct: 72 PG-TENFHYEMELALAIGASAFRASPEEARAAIYGYGCALDMTRRDLQIRERQKQRPWDL 130 Query: 180 GKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVM 239 GK ++ L P SD G E + L+G +KQ ++ A+L+ S ++ +S Sbjct: 131 GKDLEQGTVLAPFTKASDW-GPVAEQPIWLELDGEIKQDATLAELIWSCEEIICHLSCYY 189 Query: 240 TLVPGDLILTGTPGGVG 256 L PGD+ILTGTP GVG Sbjct: 190 HLQPGDIILTGTPAGVG 206 >UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; Alphaproteobacteria|Rep: Possible isomerase/decarboxylase - Rhodopseudomonas palustris Length = 329 Score = 92.3 bits (219), Expect = 1e-17 Identities = 51/162 (31%), Positives = 88/162 (54%), Gaps = 3/162 (1%) Query: 128 VDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQF--LLGKSMDT 185 +D+E+E ++ R+ + + A H+ GYT+ D SARD Q+ + G+ GKS D Sbjct: 166 MDYELEFGIITKRKGANISAAQAKNHIFGYTIFNDFSARDAQRIEMEGRLGPAKGKSFDG 225 Query: 186 FCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGD 245 +GP ++T DE+G L + +NG ++ T ++ S ++ +S TL+PG+ Sbjct: 226 GNVIGPWIVTPDEIGDPYRLNMEARVNGEVRSRGVTEGMLFSFEEIIAHVSRDETLMPGE 285 Query: 246 LILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 I +GT G G + +L+ GDV+ E+EKIG ++E+ Sbjct: 286 FIGSGTVGN-GCGLELGWFLEHGDVIELEVEKIGIPKNKVER 326 >UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Nocardioides sp. JS614|Rep: Fumarylacetoacetate (FAA) hydrolase - Nocardioides sp. (strain BAA-499 / JS614) Length = 280 Score = 92.3 bits (219), Expect = 1e-17 Identities = 59/184 (32%), Positives = 97/184 (52%), Gaps = 9/184 (4%) Query: 100 VPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTV 159 +P + T+IGP+ + T+++D E+EL V+GR + E++AL HV GYT+ Sbjct: 91 LPAYYKGLPDTVIGPEDEIPWPA-YTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTI 149 Query: 160 AQDISARDWQKEK---NMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLK 216 D+SARD Q + MG K D LGPC++T+DEV ++ + +NG Sbjct: 150 WNDLSARDVQAGELPVGMGPG-KAKDWDGSNVLGPCIVTADEVDPH-DIELEVRVNGERW 207 Query: 217 QSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGT-PGGVGMYRQPPEYLQPGDVLTSEI 275 ++T + H+ S++ S + L PG+++ +GT GG G+ + +L P D + E Sbjct: 208 GGANTRDMHHTFESMIVYASQALMLRPGEVLGSGTATGGSGV--ELGRWLAPADTVEMEA 265 Query: 276 EKIG 279 IG Sbjct: 266 SGIG 269 >UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xanthomonadaceae|Rep: Fumarylacetoacetate hydrolase - Xanthomonas oryzae pv. oryzae Length = 290 Score = 91.1 bits (216), Expect = 3e-17 Identities = 67/214 (31%), Positives = 103/214 (48%), Gaps = 20/214 (9%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPV------PMVFSKFSSTIIGPDQPVRIRTDVTKKVD 129 V +I C+G N+ DH +E + P P F K + I+ TK++ Sbjct: 77 VHRIYCVGRNFADHAREMGASAPASKAERGQPTFFMKPADAIVVGHGDQIPYPPGTKELH 136 Query: 130 WEVELCVVVGREASC--VREEDALQHVAGYTVAQDISARDWQ---KEKNMGQFLLGKSMD 184 EVEL V +G +A + E A + + GY V D++ RD Q K K + + + K D Sbjct: 137 HEVELVVALGSDAPAGELPVEQAERLIYGYGVGLDLTRRDLQAAAKAKGL-PWDIAKGFD 195 Query: 185 TFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPG 244 P+ V + EVG L +S +NG ++Q S Q++ ++P +LH +S + L G Sbjct: 196 HSAPISELV-HAGEVGVLEALNLSLEVNGQVRQQSLLDQMIWNVPEILHALSKLYALRAG 254 Query: 245 DLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKI 278 DLI GTP GVG L PGD ++ +E + Sbjct: 255 DLIFMGTPAGVGP-------LLPGDQFSARLENV 281 >UniRef50_Q1QDY9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Psychrobacter|Rep: Fumarylacetoacetate (FAA) hydrolase - Psychrobacter cryohalolentis (strain K5) Length = 238 Score = 91.1 bits (216), Expect = 3e-17 Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 11/203 (5%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQP-VRIRTDVTKKVDWEVEL 134 + K++C+G NY +H +E P P++F K +S+++ VR + +E EL Sbjct: 34 IGKVICVGRNYAEHARELGNEIPKSPILFMKPASSVVSVHNDIVRPNPALYGDTHYEAEL 93 Query: 135 CVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQ-FLLGKSMDTFCPLGPC 192 C+ + + S E A Q + G T+ D++ RD Q K K G + K D C L Sbjct: 94 CIQLAADLSAATIEQAKQAIGGVTLGLDLTLRDLQSKLKEKGHPWERAKCFDGACVLADW 153 Query: 193 VLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252 + G + +N LKQ +A ++ + LL IS +L GD+I+TGTP Sbjct: 154 I-DPQAFGDFCHVEYQLYINDELKQDGDSALMLFPVYELLAEISHAFSLQAGDVIMTGTP 212 Query: 253 GGVGMYRQPPEYLQPGDVLTSEI 275 GVG+ LQ D LT ++ Sbjct: 213 SGVGV-------LQAADTLTFKL 228 >UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Marinomonas sp. MWYL1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Marinomonas sp. MWYL1 Length = 245 Score = 91.1 bits (216), Expect = 3e-17 Identities = 56/189 (29%), Positives = 98/189 (51%), Gaps = 9/189 (4%) Query: 91 QEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDA 150 ++ ++ PP P++ K +T IG + +++ +D V L +V+G++ + V +A Sbjct: 57 EKPHVQPPKTPVLHIKTDNTHIGYGKSIKLPSD-KGAVFAGPSLGIVIGKKTTRVDASNA 115 Query: 151 LQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCS 210 L VAG+TV ++S + + + K DTFCP+GP + V +L + Sbjct: 116 LDCVAGFTVVNEVSLAETSFYRPA---VKAKCRDTFCPIGPWSVDKSAVSTPNKLSIKTF 172 Query: 211 LNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDV 270 +N L ++T QL++S+ ++ ISS MTL GD+I+ GTP R + PGD Sbjct: 173 INDALVHETNTDQLIYSVEEIVSYISSFMTLEAGDIIIAGTP-----ERTADLAINPGDS 227 Query: 271 LTSEIEKIG 279 + +IE +G Sbjct: 228 VMIDIEGVG 236 >UniRef50_Q7NUB2 Cluster: Probable isomerase; n=3; Betaproteobacteria|Rep: Probable isomerase - Chromobacterium violaceum Length = 216 Score = 90.6 bits (215), Expect = 4e-17 Identities = 67/197 (34%), Positives = 92/197 (46%), Gaps = 10/197 (5%) Query: 64 LSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTD 123 +SSV L V I CIG NY H E P+VF K +S ++ P+R+ + Sbjct: 1 MSSVKLGLHAIRVGNIFCIGRNYAAHAAELGNKVEDEPLVFLKPTSALLDESSPIRL-PE 59 Query: 124 VTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKE-KNMGQ-FLLGK 181 + V E EL ++G+ + E AL HVAGY + D++ARD Q E K GQ + K Sbjct: 60 YSGDVHHECELVALIGKGGDDIPPEKALDHVAGYGIGLDLTARDAQAEAKRKGQPWTKAK 119 Query: 182 SM-DTFC--PLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSV 238 C L P D ELRV NG L+Q ++ ++ + +S + Sbjct: 120 GFRGAACVSTLVPAARVEDPQRLKFELRV----NGQLRQRGDAGLMLFTLAEQISYLSRL 175 Query: 239 MTLVPGDLILTGTPGGV 255 L GDLI TGTP GV Sbjct: 176 YGLSDGDLIFTGTPEGV 192 >UniRef50_O86346 Cluster: POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE) + CYCLASE/DEHYDRASE; n=9; Mycobacterium|Rep: POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE) + CYCLASE/DEHYDRASE - Mycobacterium tuberculosis Length = 644 Score = 89.4 bits (212), Expect = 9e-17 Identities = 86/285 (30%), Positives = 132/285 (46%), Gaps = 25/285 (8%) Query: 16 RVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHG 75 R G L GD I + D SL L+ +G ++ + A + L VTL API Sbjct: 13 RTGVLSGDAIYAM-PPDVSL-LDLVGRGADGLRTAGERAVRSPAAVVALDEVTLAAPIPR 70 Query: 76 VDKI---LCIGLNYKDHCQEQNL-------TPPPVPMVFSKFSSTIIGPDQPVRIRTDVT 125 I LC L++ +CQE T +P + ST++GP Sbjct: 71 PPSIRDSLCF-LDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYDDAPTAPGSA 129 Query: 126 KKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDT 185 + D+E+E+ V+G + E A + + GYT+ D SARD Q + + K D+ Sbjct: 130 WQ-DFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDS 188 Query: 186 FCPLGPCVLTSDEV-----GAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 LGP ++T DE+ G + LRV +NG + S STAQ+ S ++ S +T Sbjct: 189 GITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVIAYASRGVT 248 Query: 241 LVPGDLILTGTPGGVGM--YRQPPE----YLQPGDVLTSEIEKIG 279 L PGD+ +GT + + +PPE +L GDV+T ++E +G Sbjct: 249 LTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLG 293 >UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Vibrio shilonii AK1|Rep: Fumarylacetoacetate (FAA) hydrolase - Vibrio shilonii AK1 Length = 264 Score = 89.4 bits (212), Expect = 9e-17 Identities = 64/226 (28%), Positives = 101/226 (44%), Gaps = 20/226 (8%) Query: 62 IPLSSVTLTAPI-HGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 120 I TL API HG + +GLN++ H P + F + + Sbjct: 58 ITADEATLLAPITHG--SVYAVGLNFRSHAGNSGAAKPEI--FFKSIDAVRLSGALSF-- 111 Query: 121 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 180 D V +E EL +V+G+ ++AL V GY D++ R WQ + Q+ Sbjct: 112 -PDEANNVHFEGELVIVIGKTCHDTSNQNALSCVFGYLAGNDLTERSWQGQDL--QWWRA 168 Query: 181 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 K F P+ + T+ ++G + LNG + Q + A ++H++P+++ IS +T Sbjct: 169 KGATGFGPVSNFITTNVDIG---NQEIVTRLNGKIMQQETLANMIHNVPTIVSYISKYIT 225 Query: 241 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIE 286 L PGD+I GTPG L+ GD ++ IE IG IE Sbjct: 226 LRPGDMIFAGTPGRT-------RALRSGDNVSVSIEGIGQVSNTIE 264 >UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase precursor; n=4; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase precursor - Polaromonas naphthalenivorans (strain CJ2) Length = 245 Score = 89.0 bits (211), Expect = 1e-16 Identities = 66/230 (28%), Positives = 107/230 (46%), Gaps = 17/230 (7%) Query: 59 PATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPV 118 PAT+ ++ T P V ++ CIG NY+ + P +P F K ++ ++ V Sbjct: 14 PATVAVAGSTAVFP---VGRVFCIGRNYR--WSQDEAMPQEMPAWFMKPANAVVHA-HGV 67 Query: 119 RIRTDVTKKVDWEVELCVVVGREASCVREEDAL-QHVAGYTVAQDISARDWQKEKNM--G 175 T E+EL V +GR + H+ GY D++ RD Q++ G Sbjct: 68 LPYPPATGDFCHEIELVVAIGRGGRDIAPAQVEPHHIWGYAAGLDLTRRDLQQQAKRAGG 127 Query: 176 QFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRI 235 + K+ D P P V + G + V ++NG+ +Q + + L+ + L+ + Sbjct: 128 PWEAAKAFDHSAPCTPLVPAA-ACGHPRQGAVWLTVNGIERQRADVSGLLWPVAELVAML 186 Query: 236 SSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 S +TL+PGDLI TGTP GVG LQPGDV+ + +G F + + Sbjct: 187 SRSVTLMPGDLIYTGTPAGVGP-------LQPGDVVQGGVAGVGQFSMTV 229 >UniRef50_Q5P741 Cluster: Fumarylpyruvate hydrolase; n=14; Proteobacteria|Rep: Fumarylpyruvate hydrolase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 236 Score = 87.8 bits (208), Expect = 3e-16 Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 14/215 (6%) Query: 76 VDKILCIGLNYKDHCQEQNLTPPPV---PMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEV 132 ++++ +G NY H E P F+K ST+ V TK +E+ Sbjct: 27 INRLFFVGRNYYAHSVEMGNPVDKATSRPFYFTKAPSTLTESGATVAYPPG-TKNFHYEM 85 Query: 133 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-EKNMGQ-FLLGKSMDTFCPLG 190 EL V +G V E DA + + GY D++ RD Q + G+ + LGK ++ + Sbjct: 86 ELVVAIGAPGFRVAEADAEKLIYGYACGLDMTRRDLQLVAREAGRPWDLGKDVEQ-SSVA 144 Query: 191 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 250 ++ E+G + ++ +NG KQSS + L+ SIP ++ +S L PGDLI TG Sbjct: 145 SEIVPKGELGVVSQGALTLVVNGQTKQSSDVSLLIWSIPEIIADLSQFYHLQPGDLIYTG 204 Query: 251 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 TP GVG + PGD L+ IE IG + I Sbjct: 205 TPEGVGA-------VNPGDRLSGRIEGIGEISLLI 232 >UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2; probable 5- oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2; n=1; Natronomonas pharaonis DSM 2160|Rep: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2; probable 5- oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 319 Score = 87.8 bits (208), Expect = 3e-16 Identities = 57/223 (25%), Positives = 115/223 (51%), Gaps = 13/223 (5%) Query: 67 VTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPP-----VPMVFSKFSSTIIGPDQPVRIR 121 V+L AP+ + + + +++H + PP +P+ + + +++ P + V Sbjct: 99 VSLLAPVPRPNSLRDF-MVFEEHVRNALGEEPPDAWYEMPVYYKSTADSVVAPGETVEWP 157 Query: 122 TDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGK 181 + +D+E+EL V+G+E + E A +++AGYT+ D SARD Q E+ + K Sbjct: 158 A-YSSLMDYELELAAVIGKEGRDIPAEAADEYIAGYTIFNDFSARDIQGEEMQARLGPAK 216 Query: 182 SMDTFCPLGPCVLTSDEVG-AAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 240 D GP ++T+D+ E+R ++NG + + ++ H+ ++ +S T Sbjct: 217 GKDFANAFGPYLVTADDFDPETAEMR--ATVNGEVWSEGTPGEMYHTFADIVAHVSQSET 274 Query: 241 LVPGDLILTGTPG-GVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 L PGD++ +GT G G G+ + ++L+ GD ++ ++ IG + Sbjct: 275 LYPGDVLGSGTVGEGCGL--ELGQFLESGDTVSLFVDGIGTLE 315 >UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate (FAA) hydrolase - Sphingomonas wittichii RW1 Length = 317 Score = 87.0 bits (206), Expect = 5e-16 Identities = 54/166 (32%), Positives = 81/166 (48%), Gaps = 5/166 (3%) Query: 125 TKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFL--LGKS 182 T +D+E+E +VG+ + A H+ GYT+ D+SARD Q GQ GK Sbjct: 149 TDWMDFELEWACIVGKGGRNISPAQARAHIFGYTIFNDLSARDVQLAVMAGQIGPGAGKD 208 Query: 183 MDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLV 242 D P+GPC++T+D + L ++ S+NG STA + HS + +S L Sbjct: 209 FDNSNPIGPCIVTADAIPDPYALAMTASVNGEQWSRGSTASMHHSFEDAVVMLSRDRQLH 268 Query: 243 PGDLILTGTP-GGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEK 287 G++I +GT G G Q L PGDV+ +E IG + + Sbjct: 269 AGEIIASGTVLTGCGFELQ--RRLSPGDVVELYVEAIGTLTTTVRR 312 >UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Sphingomonas wittichii RW1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Sphingomonas wittichii RW1 Length = 276 Score = 86.6 bits (205), Expect = 6e-16 Identities = 54/176 (30%), Positives = 84/176 (47%), Gaps = 8/176 (4%) Query: 78 KILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRIRTDVTKKVDWEVELCVV 137 K + IG+NY+ + + P P+V+ + + IIG + + D V E EL V Sbjct: 76 KYVGIGINYRATAEALGMAMPEEPVVYVRPPNCIIGDGDRIVLPAD--GDVVCEGELAAV 133 Query: 138 VGREASCVREEDALQHVAGYTVAQDI-SARDWQKEKNMGQFLLGKSMDTFCPLGPCVLTS 196 +GR + E D HV GYT+ D+ + K+K G L K D F PLGPC+ T Sbjct: 134 IGRRGRDIAEGDVAAHVIGYTLTNDLMDVARFHKDK--GNPSLAKGRDGFAPLGPCIATG 191 Query: 197 DEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTP 252 ++ A ++ +NG Q+ ++ + + IS MTL PGD++ G P Sbjct: 192 LDLATA---ELATFVNGARVQAGFARDMLFGVERCVSHISRFMTLEPGDVVALGCP 244 >UniRef50_Q4WH18 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Aspergillus fumigatus|Rep: Fumarylacetoacetate hydrolase family protein - Aspergillus fumigatus (Sartorya fumigata) Length = 249 Score = 86.2 bits (204), Expect = 9e-16 Identities = 52/157 (33%), Positives = 84/157 (53%), Gaps = 5/157 (3%) Query: 133 ELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQ-KEKNMGQFLLGKSMDTFCPLGP 191 ELC V RE + E+A + GYT+ D+S R +Q E++ GQF K+ D F P+GP Sbjct: 84 ELCFVTSRECRDLSIEEAPSCILGYTIGNDLSCRFFQLPEQSGGQFFYAKAFDRFAPVGP 143 Query: 192 CVLTSDEVGAAVE--LRVSCSLNGVLKQSSS-TAQLVHSIPSLLHRISSVMTLVPGDLIL 248 VL V E R+ +NG +KQ S + ++++ +L +S T+ +++ Sbjct: 144 -VLVHPSVWHKAEKTARLVTRVNGHVKQDSHLSTDMINTPARILSWMSQGTTIPAYTILM 202 Query: 249 TGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 TGTP GVG ++ P ++L+ D + EI +G R+ Sbjct: 203 TGTPAGVGAFQTPRQFLKDKDSVDVEITGLGVLQNRV 239 Score = 35.5 bits (78), Expect = 1.6 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%) Query: 32 DSSLPTTLLQILRNGDLEKVKKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQ 91 DS+ P T QI E +K+ K+ I + + P+H + I C+GLNYK H + Sbjct: 23 DSTEPLTGAQINAYRSFEDLKERKNGVIRAI--AKLLPPVPVHDLP-IYCVGLNYKSHAK 79 Query: 92 EQN 94 E N Sbjct: 80 EAN 82 >UniRef50_A4YZ43 Cluster: Putative Fumarylacetoacetate hydrolase family protein; n=3; Proteobacteria|Rep: Putative Fumarylacetoacetate hydrolase family protein - Bradyrhizobium sp. (strain ORS278) Length = 264 Score = 85.4 bits (202), Expect = 1e-15 Identities = 70/243 (28%), Positives = 111/243 (45%), Gaps = 23/243 (9%) Query: 52 KKLKSTKPATIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSST 110 K + + TIP++ P+ +I CIG NY H E+ P P F K + Sbjct: 35 KPIFAVAATTIPIAGEQGVFPVR---RIYCIGRNYAAHAIERGSDPNREPPFFFQKPTDA 91 Query: 111 I----IGP--DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDIS 164 I +G D P +TK EVEL + + + E AL HV GY + D++ Sbjct: 92 IQNVAVGEVADHPY---PSLTKNYHHEVELVAALKSGGTNIPVESALDHVYGYALGLDMT 148 Query: 165 ARDWQK--EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTA 222 RD Q + +GKS D +GP S+ VG + +S ++NG ++QSS Sbjct: 149 RRDLQNGMAAEKKPWEIGKSFDHAAVIGPIHPVSN-VGHFTKGAISLAVNGTVRQSSDLT 207 Query: 223 QLVHSIPSLLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFD 282 +++ S+ + ++S L GD+I +GTP VG + GDVL ++E + Sbjct: 208 KMIWSVAEQIAKLSEAFELKAGDIIYSGTPENVGP-------VVKGDVLLCKLEGLPDMS 260 Query: 283 VRI 285 ++I Sbjct: 261 IKI 263 >UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family protein; n=15; Ascomycota|Rep: Fumarylacetoacetate hydrolase family protein - Aspergillus fumigatus (Sartorya fumigata) Length = 235 Score = 85.4 bits (202), Expect = 1e-15 Identities = 73/205 (35%), Positives = 105/205 (51%), Gaps = 22/205 (10%) Query: 84 LNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQ-PVRIRTDVTKKVDWEVELCVVVG--- 139 LN +E N T P P F K S+I+ P + PV + V+ + +EVEL +V+G Sbjct: 20 LNKSQLQKELNNTKPKQPFFFLKPPSSILLPREGPVLLPKGVS--LHYEVELALVMGKTV 77 Query: 140 REASCVREEDALQHVAGYTVAQDISARDWQKE-KNMG-QFLLGKSMDTFCPLG---PCVL 194 R+ E+ AL + Y +A D++ R+ Q E K G + + K DTF P+ P Sbjct: 78 RDLDPNDEKGALDAIRSYLLAIDMTGRNVQDEAKKKGLPWSIAKGFDTFLPISEEIPKAR 137 Query: 195 TSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTGTPGG 254 D A + L S+ L+Q+ ST +++ IP L IS VMTL GDL+LTGTP G Sbjct: 138 IPDPHNAFLRL----SVGSQLRQADSTGLMLYRIPRQLAEISRVMTLEKGDLVLTGTPKG 193 Query: 255 VGMYRQPPEYLQPGDVLTSEIEKIG 279 VG ++ GDV+ + IE G Sbjct: 194 VG-------EVKAGDVMKASIEVDG 211 >UniRef50_Q89FA1 Cluster: Bll6800 protein; n=3; Proteobacteria|Rep: Bll6800 protein - Bradyrhizobium japonicum Length = 276 Score = 85.0 bits (201), Expect = 2e-15 Identities = 66/235 (28%), Positives = 110/235 (46%), Gaps = 22/235 (9%) Query: 62 IPLSSVTLTAP--IHGVDKILCIGLNYKDHCQEQNLTPP-PVPMVFSKFSSTI----IGP 114 +P+ ++ + + V +I CIG NY H E+ P P F K + I +G Sbjct: 52 VPMVAIPIVGETQVFQVRRIYCIGRNYAAHAIERGSDPNREPPFFFQKPTDAIQNVAVGE 111 Query: 115 --DQPVRIRTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQK-- 170 D P +TK E+EL + + + E AL HV GY + D++ RD Q Sbjct: 112 VADHPY---PSLTKNYHHEIELVAALKSGGTNIPAEKALDHVYGYALGLDMTRRDLQNGM 168 Query: 171 EKNMGQFLLGKSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPS 230 + +GKS D LGP + + + G + +S ++NG +KQSS ++++ S+ Sbjct: 169 AAEKKPWEIGKSFDHAAVLGP-IHPASKTGHFEKGAISLAINGTVKQSSDLSKMIWSVAE 227 Query: 231 LLHRISSVMTLVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRI 285 + ++S L GD+I +GTP VG + GDVL ++E + ++I Sbjct: 228 QIAKLSEAFELKAGDIIYSGTPENVGP-------VVKGDVLLCKLEGLPDMSIKI 275 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.317 0.136 0.397 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 333,794,440 Number of Sequences: 1657284 Number of extensions: 14078967 Number of successful extensions: 34335 Number of sequences better than 10.0: 350 Number of HSP's better than 10.0 without gapping: 316 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 33328 Number of HSP's gapped (non-prelim): 389 length of query: 288 length of database: 575,637,011 effective HSP length: 100 effective length of query: 188 effective length of database: 409,908,611 effective search space: 77062818868 effective search space used: 77062818868 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 72 (33.1 bits)
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