Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000060-TA|BGIBMGA000060-PA|IPR003018|GAF,
IPR002073|3'5'-cyclic nucleotide phosphodiesterase, IPR001998|Xylose
isomerase, IPR003607|Metal-dependent phosphohydrolase, HD region
(852 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VFI9 Cluster: CG8279-PA; n=8; Endopterygota|Rep: CG82... 967 0.0
UniRef50_Q3SBD3 Cluster: Sperm phosphodiesterase 5; n=1; Strongy... 693 0.0
UniRef50_Q9VJ79 Cluster: Dual 3',5'-cyclic-AMP and -GMP phosphod... 553 e-156
UniRef50_Q7Q8G2 Cluster: ENSANGP00000013023; n=2; Diptera|Rep: E... 536 e-150
UniRef50_O76074 Cluster: cGMP-specific 3',5'-cyclic phosphodiest... 492 e-137
UniRef50_Q4SVG8 Cluster: Chromosome undetermined SCAF13758, whol... 465 e-129
UniRef50_Q9HCR9 Cluster: Dual 3',5'-cyclic-AMP and -GMP phosphod... 450 e-125
UniRef50_UPI0000D8B81A Cluster: UPI0000D8B81A related cluster; n... 393 e-108
UniRef50_P16499 Cluster: Rod cGMP-specific 3',5'-cyclic phosphod... 378 e-103
UniRef50_Q16HU8 Cluster: Camp and camp-inhibited cgmp 3,5-cyclic... 359 2e-97
UniRef50_UPI0000F1D4E2 Cluster: PREDICTED: similar to Phosphodie... 346 2e-93
UniRef50_Q4RHZ1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 328 4e-88
UniRef50_Q9Y233 Cluster: cAMP and cAMP-inhibited cGMP 3',5'-cycl... 317 7e-85
UniRef50_UPI000065DEB3 Cluster: Dual 3',5'-cyclic-AMP and -GMP p... 307 1e-81
UniRef50_P91119 Cluster: Probable 3',5'-cyclic phosphodiesterase... 305 4e-81
UniRef50_O00408 Cluster: cGMP-dependent 3',5'-cyclic phosphodies... 305 4e-81
UniRef50_Q4RG61 Cluster: Chromosome 2 SCAF15106, whole genome sh... 298 3e-79
UniRef50_O96076 Cluster: EFPDE2; n=1; Ephydatia fluviatilis|Rep:... 291 5e-77
UniRef50_A7SW30 Cluster: Predicted protein; n=2; Nematostella ve... 281 7e-74
UniRef50_UPI0000E48F4D Cluster: PREDICTED: similar to camp and c... 280 1e-73
UniRef50_UPI00015B4531 Cluster: PREDICTED: similar to cyclic GMP... 266 2e-69
UniRef50_UPI0000588CD9 Cluster: PREDICTED: hypothetical protein;... 254 1e-65
UniRef50_Q4RNP2 Cluster: Chromosome 2 SCAF15010, whole genome sh... 252 3e-65
UniRef50_Q17L35 Cluster: Cgmp-dependent 3,5-cyclic phosphodieste... 239 3e-61
UniRef50_A2F408 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 223 2e-56
UniRef50_A2FKH2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 221 5e-56
UniRef50_A2DF08 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 220 1e-55
UniRef50_A2DYU6 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 217 1e-54
UniRef50_A2D762 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 212 3e-53
UniRef50_A2DG30 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 212 4e-53
UniRef50_P30645 Cluster: Probable 3',5'-cyclic phosphodiesterase... 209 3e-52
UniRef50_A2E8N2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 208 5e-52
UniRef50_A2FQ29 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 204 8e-51
UniRef50_A2FBN7 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 204 1e-50
UniRef50_UPI0000D555D7 Cluster: PREDICTED: similar to phosphodie... 203 2e-50
UniRef50_A2EIP4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 203 2e-50
UniRef50_UPI000065E700 Cluster: Cone cGMP-specific 3',5'-cyclic ... 201 6e-50
UniRef50_Q6S996 Cluster: Class I phosphodiesterase PDEB1; n=21; ... 200 1e-49
UniRef50_A2EY05 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 199 3e-49
UniRef50_A2G2M9 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 195 5e-48
UniRef50_A2ENJ2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 194 8e-48
UniRef50_A2ERL4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 188 6e-46
UniRef50_A2DNV4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 183 2e-44
UniRef50_Q7PQX7 Cluster: ENSANGP00000010843; n=6; Coelomata|Rep:... 173 1e-41
UniRef50_UPI0000D577EC Cluster: PREDICTED: similar to CG32648-PA... 172 3e-41
UniRef50_Q16VA1 Cluster: High-affinity cgmp-specific 3,5-cyclic ... 170 1e-40
UniRef50_UPI00015B464B Cluster: PREDICTED: similar to ENSANGP000... 170 2e-40
UniRef50_Q9VYJ0 Cluster: CG32648-PA; n=3; Coelomata|Rep: CG32648... 169 3e-40
UniRef50_Q23917 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 168 5e-40
UniRef50_A2F9J4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 163 2e-38
UniRef50_A7SVS5 Cluster: Predicted protein; n=1; Nematostella ve... 159 3e-37
UniRef50_A2EHB3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 159 4e-37
UniRef50_Q8I6Y6 Cluster: CGMP-specific phosphodiesterase; n=3; D... 158 5e-37
UniRef50_O76083 Cluster: High affinity cGMP-specific 3',5'-cycli... 157 9e-37
UniRef50_Q4SVG0 Cluster: Chromosome 1 SCAF13759, whole genome sh... 157 1e-36
UniRef50_A2DJF3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 157 1e-36
UniRef50_A2FQB0 Cluster: GAF domain containing protein; n=1; Tri... 151 8e-35
UniRef50_A2E5S0 Cluster: GAF domain containing protein; n=1; Tri... 147 1e-33
UniRef50_UPI00006CBCA5 Cluster: 3''''5''''-cyclic nucleotide pho... 144 7e-33
UniRef50_UPI00015B4893 Cluster: PREDICTED: similar to camp-speci... 136 2e-30
UniRef50_UPI0000DB7125 Cluster: PREDICTED: similar to Phosphodie... 135 4e-30
UniRef50_A7SGA1 Cluster: Predicted protein; n=1; Nematostella ve... 135 4e-30
UniRef50_A4RV03 Cluster: Predicted protein; n=1; Ostreococcus lu... 134 7e-30
UniRef50_Q14123 Cluster: Calcium/calmodulin-dependent 3',5'-cycl... 134 9e-30
UniRef50_Q005X2 Cluster: Phosphodiesterase 1; n=1; Strongylocent... 133 2e-29
UniRef50_UPI000150A113 Cluster: 3''''5''''-cyclic nucleotide pho... 132 3e-29
UniRef50_Q4KL87 Cluster: MGC116558 protein; n=2; Xenopus|Rep: MG... 132 4e-29
UniRef50_P27815 Cluster: cAMP-specific 3',5'-cyclic phosphodiest... 132 4e-29
UniRef50_O18696 Cluster: Probable 3',5'-cyclic phosphodiesterase... 132 4e-29
UniRef50_Q23AZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 132 5e-29
UniRef50_Q8SXR0 Cluster: RE69157p; n=9; Coelomata|Rep: RE69157p ... 130 1e-28
UniRef50_O96075 Cluster: EFPDE1; n=1; Ephydatia fluviatilis|Rep:... 130 2e-28
UniRef50_Q23RI8 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 128 8e-28
UniRef50_A4HHP3 Cluster: Putative uncharacterized protein; n=3; ... 127 1e-27
UniRef50_A2FK96 Cluster: GAF domain containing protein; n=3; Tri... 126 3e-27
UniRef50_UPI0000D56333 Cluster: PREDICTED: similar to cGMP-depen... 126 3e-27
UniRef50_Q13946 Cluster: High affinity cAMP-specific 3',5'-cycli... 125 4e-27
UniRef50_UPI0000D56A7E Cluster: PREDICTED: similar to High-affin... 124 8e-27
UniRef50_A5JZK2 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 123 2e-26
UniRef50_Q4D500 Cluster: Phosphodiesterase, putative; n=3; Trypa... 122 5e-26
UniRef50_UPI00015B5210 Cluster: PREDICTED: similar to ENSANGP000... 121 9e-26
UniRef50_Q57V52 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 121 9e-26
UniRef50_A2E0V4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 121 9e-26
UniRef50_A2FET3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 120 1e-25
UniRef50_Q16J23 Cluster: Camp-specific 3,5-cyclic phosphodiester... 120 2e-25
UniRef50_UPI0000DB6B8B Cluster: PREDICTED: similar to phosphodie... 120 2e-25
UniRef50_Q6S998 Cluster: CAMP-specific phosphodiesterase; n=3; L... 120 2e-25
UniRef50_Q9N2V9 Cluster: Probable 3',5'-cyclic phosphodiesterase... 120 2e-25
UniRef50_A0EHP5 Cluster: Chromosome undetermined scaffold_97, wh... 119 3e-25
UniRef50_Q22CV4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 118 5e-25
UniRef50_A2DBZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 118 9e-25
UniRef50_Q13945 Cluster: 3',5'-cyclic AMP phosphodiesterase; n=3... 118 9e-25
UniRef50_Q53S13 Cluster: Putative uncharacterized protein PDE11A... 117 1e-24
UniRef50_Q22000 Cluster: Probable 3',5'-cyclic phosphodiesterase... 117 2e-24
UniRef50_A7AR41 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 116 2e-24
UniRef50_A7SYX3 Cluster: Predicted protein; n=1; Nematostella ve... 116 4e-24
UniRef50_O96077 Cluster: EFPDE3; n=1; Ephydatia fluviatilis|Rep:... 115 5e-24
UniRef50_Q4N6H0 Cluster: Putative uncharacterized protein; n=1; ... 115 6e-24
UniRef50_Q4RH59 Cluster: Chromosome undetermined SCAF15069, whol... 114 1e-23
UniRef50_A0E2C5 Cluster: Chromosome undetermined scaffold_74, wh... 114 1e-23
UniRef50_O96078 Cluster: EFPDE4; n=1; Ephydatia fluviatilis|Rep:... 113 1e-23
UniRef50_A0DIM1 Cluster: Chromosome undetermined scaffold_52, wh... 113 1e-23
UniRef50_A0CZ03 Cluster: Chromosome undetermined scaffold_31, wh... 113 2e-23
UniRef50_A2GFY4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 113 3e-23
UniRef50_A2DM77 Cluster: GAF domain containing protein; n=1; Tri... 113 3e-23
UniRef50_A2DM90 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 112 4e-23
UniRef50_UPI0000519BD4 Cluster: PREDICTED: similar to phosphodie... 111 6e-23
UniRef50_A0E1V7 Cluster: Chromosome undetermined scaffold_74, wh... 111 1e-22
UniRef50_UPI000150A9A4 Cluster: 3''''5''''-cyclic nucleotide pho... 110 1e-22
UniRef50_A0CG66 Cluster: Chromosome undetermined scaffold_179, w... 110 2e-22
UniRef50_UPI00006CF33D Cluster: 3''''5''''-cyclic nucleotide pho... 109 3e-22
UniRef50_Q6NNF2 Cluster: SD02170p; n=9; Diptera|Rep: SD02170p - ... 109 3e-22
UniRef50_A0EGK4 Cluster: Chromosome undetermined scaffold_95, wh... 109 4e-22
UniRef50_Q4T098 Cluster: Chromosome undetermined SCAF11274, whol... 108 7e-22
UniRef50_Q9W4T4 Cluster: cAMP-specific 3',5'-cyclic phosphodiest... 108 7e-22
UniRef50_A7AS42 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 107 1e-21
UniRef50_Q388U6 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 106 2e-21
UniRef50_A7SVX8 Cluster: Predicted protein; n=1; Nematostella ve... 106 2e-21
UniRef50_A4VDP2 Cluster: Cyclic nucleotide phosphodiesterase; n=... 106 2e-21
UniRef50_UPI0000E7FF0E Cluster: PREDICTED: similar to cAMP phosp... 105 4e-21
UniRef50_A5K0J4 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 105 4e-21
UniRef50_UPI00006CB6E9 Cluster: 3''''5''''-cyclic nucleotide pho... 105 5e-21
UniRef50_Q3UEI1-2 Cluster: Isoform 2 of Q3UEI1 ; n=1; Mus muscul... 105 7e-21
UniRef50_Q5C402 Cluster: SJCHGC07495 protein; n=1; Schistosoma j... 105 7e-21
UniRef50_A2EAR4 Cluster: GAF domain containing protein; n=1; Tri... 104 9e-21
UniRef50_A0CB76 Cluster: Chromosome undetermined scaffold_163, w... 104 9e-21
UniRef50_A0DF61 Cluster: Chromosome undetermined scaffold_49, wh... 103 2e-20
UniRef50_A6S8A0 Cluster: Putative uncharacterized protein; n=2; ... 103 2e-20
UniRef50_Q4SPD6 Cluster: Chromosome 16 SCAF14537, whole genome s... 103 3e-20
UniRef50_Q01C40 Cluster: Cyclic GMP phosphodiesterase; n=1; Ostr... 103 3e-20
UniRef50_A0D565 Cluster: Chromosome undetermined scaffold_38, wh... 102 5e-20
UniRef50_A5JZK3 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 101 8e-20
UniRef50_A0EBQ7 Cluster: Chromosome undetermined scaffold_88, wh... 101 8e-20
UniRef50_A1D4A4 Cluster: High affinity cAMP phosphodiesterase, p... 101 8e-20
UniRef50_A3FQ29 Cluster: CGMP phosphodiesterase A4; n=2; Cryptos... 100 2e-19
UniRef50_O95263 Cluster: High affinity cAMP-specific and IBMX-in... 100 2e-19
UniRef50_Q8CFW8 Cluster: Phosphodiesterase 8B; n=13; Euteleostom... 99 2e-19
UniRef50_A0CZB5 Cluster: Chromosome undetermined scaffold_32, wh... 99 2e-19
UniRef50_UPI0000E46CDB Cluster: PREDICTED: similar to phosphodie... 99 4e-19
UniRef50_Q8I0P7 Cluster: Probable 3',5'-cyclic phosphodiesterase... 99 4e-19
UniRef50_A0D3N1 Cluster: Chromosome undetermined scaffold_36, wh... 98 8e-19
UniRef50_Q2H9G5 Cluster: Putative uncharacterized protein; n=1; ... 98 1e-18
UniRef50_A0CU34 Cluster: Chromosome undetermined scaffold_28, wh... 97 1e-18
UniRef50_Q4RR95 Cluster: Chromosome 14 SCAF15003, whole genome s... 97 2e-18
UniRef50_Q2V2M6 Cluster: CGMP-specific phosphodiesterase; n=3; P... 96 4e-18
UniRef50_UPI000065D378 Cluster: cAMP-specific 3',5'-cyclic phosp... 95 5e-18
UniRef50_UPI0000E47CF4 Cluster: PREDICTED: similar to camp/cgmp ... 95 9e-18
UniRef50_Q4N806 Cluster: 3',5' cyclic nucleotide phosphodiestera... 95 9e-18
UniRef50_A7RXZ4 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 94 2e-17
UniRef50_Q0V6F8 Cluster: Putative uncharacterized protein; n=1; ... 94 2e-17
UniRef50_Q14432 Cluster: cGMP-inhibited 3',5'-cyclic phosphodies... 93 3e-17
UniRef50_A2E4B2 Cluster: Response regulator receiver domain cont... 93 4e-17
UniRef50_Q1DXU2 Cluster: Putative uncharacterized protein; n=1; ... 93 4e-17
UniRef50_Q4SP32 Cluster: Chromosome 15 SCAF14542, whole genome s... 92 7e-17
UniRef50_O43851 Cluster: PDE4C-delta109; n=18; Bilateria|Rep: PD... 91 9e-17
UniRef50_Q4SI77 Cluster: Chromosome 5 SCAF14581, whole genome sh... 89 4e-16
UniRef50_Q54HY3 Cluster: Putative uncharacterized protein Pde4; ... 89 4e-16
UniRef50_A0BZK9 Cluster: Chromosome undetermined scaffold_139, w... 89 4e-16
UniRef50_Q13370 Cluster: cGMP-inhibited 3',5'-cyclic phosphodies... 88 8e-16
UniRef50_Q53I59 Cluster: Cyclic nucleotide specific phosphodiest... 87 1e-15
UniRef50_A0BZW8 Cluster: Chromosome undetermined scaffold_14, wh... 87 2e-15
UniRef50_Q01CI7 Cluster: Cyclic GMP phosphodiesterase; n=1; Ostr... 87 2e-15
UniRef50_Q4RSB8 Cluster: Chromosome 13 SCAF15000, whole genome s... 85 8e-15
UniRef50_A2FCG2 Cluster: GAF domain containing protein; n=1; Tri... 83 2e-14
UniRef50_A0EF18 Cluster: Chromosome undetermined scaffold_92, wh... 83 3e-14
UniRef50_A6R1R4 Cluster: Predicted protein; n=1; Ajellomyces cap... 83 4e-14
UniRef50_UPI000023CCA1 Cluster: hypothetical protein FG06914.1; ... 81 1e-13
UniRef50_Q7YYN8 Cluster: Phosphdiesterase, possible; n=2; Crypto... 77 2e-12
UniRef50_A3FPW6 Cluster: Phosphdiesterase, putative; n=1; Crypto... 77 2e-12
UniRef50_A7TPP3 Cluster: Putative uncharacterized protein; n=1; ... 77 2e-12
UniRef50_Q6CHK1 Cluster: Similar to tr|Q8NJP9 Candida albicans H... 77 3e-12
UniRef50_UPI0001554EBF Cluster: PREDICTED: similar to cyclic nuc... 76 4e-12
UniRef50_A4RUJ3 Cluster: Predicted protein; n=1; Ostreococcus lu... 75 6e-12
UniRef50_Q5CXM2 Cluster: Membrane associated HD superfamily cycl... 75 6e-12
UniRef50_Q57ZK5 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 75 6e-12
UniRef50_Q1JT10 Cluster: Phosphodiesterase, putative; n=2; Eukar... 73 2e-11
UniRef50_Q3KVL8 Cluster: High-affinity phosphodiesterase; n=4; E... 71 2e-10
UniRef50_Q7QRM3 Cluster: GLP_481_5888_1773; n=1; Giardia lamblia... 69 4e-10
UniRef50_A5DVX9 Cluster: Putative uncharacterized protein; n=1; ... 69 4e-10
UniRef50_Q8IKD3 Cluster: Cyclic nucleotide phosphodiesterase, pu... 69 7e-10
UniRef50_A2F4K8 Cluster: GAF domain containing protein; n=1; Tri... 68 9e-10
UniRef50_A2EA57 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 68 1e-09
UniRef50_Q758Y3 Cluster: ADR395Cp; n=1; Eremothecium gossypii|Re... 67 2e-09
UniRef50_A2EE12 Cluster: GAF domain containing protein; n=1; Tri... 67 2e-09
UniRef50_Q7RXW7 Cluster: Putative uncharacterized protein NCU004... 66 3e-09
UniRef50_A4RPY9 Cluster: Putative uncharacterized protein; n=1; ... 66 3e-09
UniRef50_A5K353 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 66 4e-09
UniRef50_A2FSQ8 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 66 5e-09
UniRef50_UPI00006CD10E Cluster: 3''''5''''-cyclic nucleotide pho... 65 7e-09
UniRef50_Q5C3V6 Cluster: SJCHGC08281 protein; n=1; Schistosoma j... 65 7e-09
UniRef50_Q6BSL2 Cluster: Similar to tr|O94034 Candida albicans N... 64 2e-08
UniRef50_A2DCH1 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 63 3e-08
UniRef50_Q5C1P7 Cluster: SJCHGC07646 protein; n=1; Schistosoma j... 62 6e-08
UniRef50_UPI00006A17C5 Cluster: cGMP-inhibited 3',5'-cyclic phos... 62 8e-08
UniRef50_Q4SV96 Cluster: Chromosome 10 SCAF13771, whole genome s... 61 1e-07
UniRef50_A2DVK5 Cluster: GAF domain containing protein; n=1; Tri... 61 1e-07
UniRef50_Q7A2D9 Cluster: Adenylate cyclase; n=6; Cyanobacteria|R... 60 2e-07
UniRef50_UPI0000660DD6 Cluster: Homolog of Homo sapiens "Phospho... 60 3e-07
UniRef50_UPI000065CC62 Cluster: cGMP-inhibited 3',5'-cyclic phos... 59 4e-07
UniRef50_A2FCG3 Cluster: GAF domain containing protein; n=1; Tri... 59 4e-07
UniRef50_Q6CY30 Cluster: Similar to sp|P06776 Saccharomyces cere... 58 8e-07
UniRef50_P06776 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 58 8e-07
UniRef50_Q29FT2 Cluster: GA17041-PA; n=1; Drosophila pseudoobscu... 57 2e-06
UniRef50_O94034 Cluster: Nucleotide phosphodiesterase; n=4; Sacc... 57 2e-06
UniRef50_UPI0001555C30 Cluster: PREDICTED: hypothetical protein,... 56 5e-06
UniRef50_Q4FXD4 Cluster: Putative uncharacterized protein; n=3; ... 55 9e-06
UniRef50_A3WDP1 Cluster: Adenylate/Guanylate Cyclase; n=1; Eryth... 52 5e-05
UniRef50_A2FYJ6 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 52 9e-05
UniRef50_Q6FM93 Cluster: Similar to sp|P06776 Saccharomyces cere... 50 3e-04
UniRef50_A0LGQ1 Cluster: Putative PAS/PAC sensor protein; n=1; S... 49 6e-04
UniRef50_A0YPV9 Cluster: Adenylate/Guanylate Cyclase; n=1; Lyngb... 48 8e-04
UniRef50_Q7M8J3 Cluster: RESPONSE REGULATOR PROTEIN-CheY-like nd... 48 0.001
UniRef50_Q4DUD4 Cluster: CAMP-specific phosphodiesterase, putati... 48 0.001
UniRef50_Q090R6 Cluster: CGMP-dependent 3',5'-cyclic phosphodies... 48 0.001
UniRef50_UPI00006CA67B Cluster: GAF domain containing protein; n... 47 0.002
UniRef50_A5V6C5 Cluster: Putative adenylate/guanylate cyclase; n... 47 0.002
UniRef50_Q4DJT7 Cluster: Putative uncharacterized protein; n=2; ... 47 0.002
UniRef50_Q24GJ8 Cluster: GAF domain containing protein; n=1; Tet... 47 0.002
UniRef50_A0NF29 Cluster: ENSANGP00000029810; n=2; Endopterygota|... 47 0.002
UniRef50_Q23PX5 Cluster: GAF domain containing protein; n=1; Tet... 46 0.003
UniRef50_A0LL31 Cluster: Serine phosphatase; n=1; Syntrophobacte... 46 0.004
UniRef50_A0LKA7 Cluster: Metal dependent phosphohydrolase; n=4; ... 46 0.004
UniRef50_Q1IM31 Cluster: Serine phosphatase; n=1; Acidobacteria ... 46 0.006
UniRef50_Q6MLW2 Cluster: NtrC family transcriptional regulator; ... 45 0.008
UniRef50_A4J938 Cluster: Metal dependent phosphohydrolase; n=1; ... 45 0.010
UniRef50_A0XZ13 Cluster: Metal dependent phosphohydrolase; n=1; ... 45 0.010
UniRef50_Q23RX8 Cluster: GAF domain containing protein; n=1; Tet... 45 0.010
UniRef50_Q22VA7 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 45 0.010
UniRef50_Q5BYM4 Cluster: SJCHGC06481 protein; n=1; Schistosoma j... 44 0.013
UniRef50_Q82SM4 Cluster: Bacterial type II secretion system prot... 44 0.017
UniRef50_A2G4P7 Cluster: GAF domain containing protein; n=1; Tri... 44 0.017
UniRef50_Q31L46 Cluster: Metal dependent phosphohydrolase; n=2; ... 43 0.030
UniRef50_Q8F1G6 Cluster: Sigma factor sigB regulation protein rs... 43 0.040
UniRef50_A4LZ56 Cluster: Diguanylate cyclase with GAF sensor; n=... 43 0.040
UniRef50_Q95Z92 Cluster: Possible phosphodiesterase; n=2; Leishm... 43 0.040
UniRef50_A6GDL8 Cluster: Sigma-54 dependent transcriptional regu... 42 0.053
UniRef50_Q8YVS0 Cluster: Adenylate cyclase; n=6; Cyanobacteria|R... 42 0.070
UniRef50_Q30S23 Cluster: Metal dependent phosphohydrolase; n=2; ... 42 0.093
UniRef50_A7AVW3 Cluster: cAMP-specific phosphodiesterase, putati... 42 0.093
UniRef50_Q2JV17 Cluster: GAF domain protein; n=2; Synechococcus|... 41 0.12
UniRef50_Q1N6Q6 Cluster: HD-GYP domain protein; n=1; Oceanobacte... 41 0.12
UniRef50_Q22SL3 Cluster: GAF domain containing protein; n=1; Tet... 41 0.12
UniRef50_A6C6H7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.16
UniRef50_A6C1F0 Cluster: Probable two-component response regulat... 41 0.16
UniRef50_A4C9A9 Cluster: Metal dependent phosphohydrolase; n=1; ... 41 0.16
UniRef50_Q5WXL9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.21
UniRef50_Q31JE4 Cluster: Metal dependent phosphohydrolase; n=1; ... 40 0.21
UniRef50_A0C3Y8 Cluster: Chromosome undetermined scaffold_148, w... 40 0.21
UniRef50_UPI0000EBF1DD Cluster: PREDICTED: similar to cGMP-speci... 40 0.28
UniRef50_A0L8S2 Cluster: Metal dependent phosphohydrolase; n=6; ... 40 0.28
UniRef50_Q4QE95 Cluster: Putative uncharacterized protein; n=3; ... 40 0.28
UniRef50_Q8EZC6 Cluster: GGDEF domain protein; n=4; Leptospira|R... 40 0.37
UniRef50_Q3JEL0 Cluster: Protein phosphatase 2C-like, stage II s... 40 0.37
UniRef50_Q2LSR2 Cluster: HD-GYP domain protein; n=1; Syntrophus ... 40 0.37
UniRef50_Q1PXJ5 Cluster: Putative uncharacterized protein; n=1; ... 40 0.37
UniRef50_A1HRZ7 Cluster: Diguanylate cyclase; n=1; Thermosinus c... 40 0.37
UniRef50_Q4N491 Cluster: Putative uncharacterized protein; n=2; ... 40 0.37
UniRef50_Q8STT1 Cluster: Putative uncharacterized protein ECU09_... 40 0.37
UniRef50_A6R8K8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.37
UniRef50_Q8DLK6 Cluster: Tlr0485 protein; n=3; Cyanobacteria|Rep... 39 0.49
UniRef50_Q31LP1 Cluster: GAF; n=2; Synechococcus elongatus|Rep: ... 39 0.49
UniRef50_A1K343 Cluster: HD-domain containing protein; n=2; Prot... 39 0.49
UniRef50_Q8CXS5 Cluster: CGMP-dependent 3',5'-cyclic phosphodies... 39 0.65
UniRef50_Q2BPD6 Cluster: Metal dependent phosphohydrolase; n=1; ... 39 0.65
UniRef50_Q01S08 Cluster: Transcriptional regulator, NifA subfami... 39 0.65
UniRef50_A1WTT3 Cluster: Metal dependent phosphohydrolase; n=1; ... 39 0.65
UniRef50_A2EAC7 Cluster: WD repeat protein, putative; n=1; Trich... 39 0.65
UniRef50_Q74EF5 Cluster: GAF domain/HD domain protein; n=4; Geob... 38 0.86
UniRef50_Q73JB6 Cluster: GAF domain/HD domain protein; n=1; Trep... 38 0.86
UniRef50_Q2WAI7 Cluster: Serine phosphatase RsbU; n=3; Magnetosp... 38 0.86
UniRef50_Q2LUL4 Cluster: General secretion pathway protein E; n=... 38 0.86
UniRef50_Q0B026 Cluster: Metal dependent phosphohydrolase; n=2; ... 38 0.86
UniRef50_A2EIQ7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.86
UniRef50_Q53E02 Cluster: TaR2; n=5; Cystobacterineae|Rep: TaR2 -... 38 1.1
UniRef50_A3ZU96 Cluster: Probable two-component response regulat... 38 1.1
UniRef50_A0W4L6 Cluster: Metal dependent phosphohydrolase; n=2; ... 38 1.1
UniRef50_A0C536 Cluster: Chromosome undetermined scaffold_15, wh... 38 1.1
UniRef50_A5UTQ7 Cluster: Sensor protein; n=1; Roseiflexus sp. RS... 38 1.5
UniRef50_A6GDA4 Cluster: Sensor protein; n=1; Plesiocystis pacif... 37 2.0
UniRef50_A0GY27 Cluster: Stage II sporulation E; n=2; Chloroflex... 37 2.0
UniRef50_UPI0000E45FE8 Cluster: PREDICTED: similar to ankyrin 2,... 37 2.6
UniRef50_A4XM27 Cluster: Diguanylate cyclase; n=1; Caldicellulos... 37 2.6
UniRef50_A7AUG1 Cluster: Putative uncharacterized protein; n=1; ... 37 2.6
UniRef50_A4CGH4 Cluster: Sensor protein; n=1; Robiginitalea bifo... 36 3.5
UniRef50_A0Q276 Cluster: Sensor protein; n=1; Clostridium novyi ... 36 3.5
UniRef50_Q4DJ46 Cluster: Putative uncharacterized protein; n=2; ... 36 3.5
UniRef50_A0L7V4 Cluster: Metal dependent phosphohydrolase precur... 36 4.6
UniRef50_Q0IWS2 Cluster: Os10g0492000 protein; n=7; Oryza sativa... 36 4.6
UniRef50_Q7UK84 Cluster: Probable two-component response regulat... 36 6.1
UniRef50_Q2BPD4 Cluster: Bacterial type II secretion system prot... 36 6.1
UniRef50_Q4SMZ1 Cluster: DNA polymerase; n=3; Deuterostomia|Rep:... 35 8.1
UniRef50_Q83A76 Cluster: GAF domain protein; n=5; Coxiella burne... 35 8.1
UniRef50_Q6YPJ5 Cluster: HD superfamily phosphohydrolase; n=2; C... 35 8.1
UniRef50_Q5L217 Cluster: Sensor protein; n=3; Bacillaceae|Rep: S... 35 8.1
UniRef50_Q1IQS3 Cluster: Sensor protein; n=1; Acidobacteria bact... 35 8.1
UniRef50_A5ZSU8 Cluster: Putative uncharacterized protein; n=1; ... 35 8.1
>UniRef50_Q9VFI9 Cluster: CG8279-PA; n=8; Endopterygota|Rep: CG8279-PA
- Drosophila melanogaster (Fruit fly)
Length = 1131
Score = 967 bits (2393), Expect = 0.0
Identities = 462/631 (73%), Positives = 516/631 (81%), Gaps = 20/631 (3%)
Query: 145 SGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLEC 204
+G EF DVE+FRRYLTFCGIGIQNAQLFE SV EY+RNQILL LARSIFEEQ+NLEC
Sbjct: 388 NGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLEC 447
Query: 205 LVTKIMTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXX 264
LVTKIMTEAR+LLKCERC+VF++D D CE+SHLE+I++
Sbjct: 448 LVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPNQPATRAIKSADSFEEKKMR 507
Query: 265 XTRFHTVFELGAP------RRPH------DALPAIALAVARSNKSLNISDVEQWLRDNNM 312
RF +FELG RP L IA VA + +++NI DV +W+RD+N
Sbjct: 508 -NRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQ 566
Query: 313 SAGENSA-GVRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIH 366
E+ + +LCMPI+NA K VIGVAQLINK FT+ D SIFEAFAIFCGLGIH
Sbjct: 567 IRAEDEIDSTQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIH 626
Query: 367 NTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLT 426
NTQMYENACKLMAKQKVALECLSYHATAS + T KL QD I AE+YNLYSF F DF+L
Sbjct: 627 NTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELV 686
Query: 427 DEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAM 486
D+DTCRA LRMF+QC LV +F IPYDVLCRW+LSV+KNYRPVKYHNWRHALNVAQTMFAM
Sbjct: 687 DDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAM 746
Query: 487 LKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTSTMEHHHFDQ 546
LKTGKMERFM+DLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY+TSTMEHHHFDQ
Sbjct: 747 LKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQ 806
Query: 547 CVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQA 606
CVMILNSE NNIFQALSP DY+ VM VE+AILSTDLAMYFKK++ FLELV+NGEFDWQ
Sbjct: 807 CVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQG 866
Query: 607 QEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDRE 666
+EKK+LLCGMMMTACDVSAIAKPWEVQH++AKLVADEFFDQGDLEKLQLN QP+AMMDRE
Sbjct: 867 EEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRE 926
Query: 667 KKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKVDMGLTWID 726
+KDELP+MQVGFID ICLPLY+VL DTFPW+TPL GT +NRR WQDLAEKV+MGLTWID
Sbjct: 927 RKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMGLTWID 986
Query: 727 HDTIDKPVEEFTA-LNEPLADVELTVTTLNC 756
HDTIDKPVEEF A +E + D+E TVTTLNC
Sbjct: 987 HDTIDKPVEEFAACADEEIKDIEFTVTTLNC 1017
Score = 78.6 bits (185), Expect = 7e-13
Identities = 33/45 (73%), Positives = 38/45 (84%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDG 95
Y +FN EID +TGYKT ILCMPICNYEGD++GVAQIINKT+G
Sbjct: 345 YKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNG 389
Score = 67.7 bits (158), Expect = 1e-09
Identities = 38/105 (36%), Positives = 57/105 (54%), Gaps = 6/105 (5%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA++ + +NI + + R N + +LCMPI N D+IGVAQ+INK
Sbjct: 328 IAGMVAQTKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKT 387
Query: 346 -----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVAL 385
F E DV IF + FCG+GI N Q++E + + + ++ L
Sbjct: 388 NGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILL 432
Score = 43.2 bits (97), Expect = 0.030
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 9/84 (10%)
Query: 22 SQLRPKTISTSGMHTPIPGKIPHKLTAIKYIT----IQFNSEIDARTGYKTELILCMPIC 77
S+L T++ G+ + I+++ I+ EID+ T+ ILCMPI
Sbjct: 531 SELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDS-----TQAILCMPIM 585
Query: 78 NYEGDVVGVAQIINKTDGEHTTES 101
N + V+GVAQ+INK +G T+S
Sbjct: 586 NAQKKVIGVAQLINKANGVPFTDS 609
>UniRef50_Q3SBD3 Cluster: Sperm phosphodiesterase 5; n=1;
Strongylocentrotus purpuratus|Rep: Sperm
phosphodiesterase 5 - Strongylocentrotus purpuratus
(Purple sea urchin)
Length = 949
Score = 693 bits (1713), Expect = 0.0
Identities = 357/679 (52%), Positives = 458/679 (67%), Gaps = 51/679 (7%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLDHNYEPRPGQI 114
+FN E+D TGYKT I+CMPICN+ DGE + Q+
Sbjct: 219 RFNPEVDKITGYKTHSIMCMPICNH--------------DGEVVGVA-----------QV 253
Query: 115 TRGPVASHWYSLYYFGNQRLYTYLRRKLSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQL 174
SH ++ ++ LRR +SH EF+ D EVF+ YLTFCGIGI NAQL
Sbjct: 254 INKITGSHEFAAK---DEEAQVELRRIVSH----EFNPADEEVFKNYLTFCGIGIMNAQL 306
Query: 175 FESSVLEYKRNQILLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILDTDHCES 234
FE SV EYKRNQ+LL LAR IFEEQ++L+ +V KIM +A LLKC+RC VFIL+T E
Sbjct: 307 FEMSVNEYKRNQMLLQLARGIFEEQTSLDNVVHKIMRQAVSLLKCQRCMVFILETT--EE 364
Query: 235 SHLE-RIVQXXXXXXXXXXXXXXXXXXXXXXXTRFHTVFELGAPRR------PHDALP-- 285
S+L ++ F FEL PH+ L
Sbjct: 365 SYLPAQLRMAEGKRHSIAYQSSFDAPLNDVKNISFLKGFELTDEDTEKLKTIPHEMLKNS 424
Query: 286 ---AIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQL 342
IA VA S ++ NI+D + +S + +R++LC PI N+ + +IGVAQ+
Sbjct: 425 INATIARHVADSGETTNIADFTVQKQFKEISDVDPEFRIRSVLCQPIYNSEQKIIGVAQM 484
Query: 343 INK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAE 397
INK FT+ D +FEAFAIFCGLGIHNTQM+ENA +LMAKQ+VAL+ LSYHATA +
Sbjct: 485 INKACKQTFTDQDEHLFEAFAIFCGLGIHNTQMFENAMRLMAKQQVALDVLSYHATAQPD 544
Query: 398 DTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRW 457
+ SKL + +PSA LY F F DFDLT++ T + TLRMF++C L+EK+HIPYDVLCRW
Sbjct: 545 EVSKLKKSCVPSARELKLYEFSFSDFDLTEDQTLQGTLRMFIECNLIEKYHIPYDVLCRW 604
Query: 458 ILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRG 517
LSV+KNYRPV YHNWRHA NVAQTMF+++ TGK+ + ++DLEI L+VACLCHDLDHRG
Sbjct: 605 TLSVRKNYRPVIYHNWRHAFNVAQTMFSIVMTGKLRKLLTDLEIFALIVACLCHDLDHRG 664
Query: 518 TNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETA 577
TNN FQ KT SPL++LY TSTMEHHHFD C+MILNSE NNIF+ +SP DY++ + ++E+A
Sbjct: 665 TNNTFQVKTSSPLSLLYGTSTMEHHHFDHCIMILNSEGNNIFEFMSPDDYREAIRMLESA 724
Query: 578 ILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIA 637
ILSTDLA+YFKK++ F +LV+ GE W +EKK LL GM+MTACDVSAIAKPW VQ ++A
Sbjct: 725 ILSTDLAIYFKKRADFFKLVEKGEHTWDNEEKKGLLRGMLMTACDVSAIAKPWLVQQKVA 784
Query: 638 KLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWM 697
+LV EFF QGDLE+ +L ++P+AMMDR+KKDELP+MQVGFID IC+P+YK+ ++ +P +
Sbjct: 785 ELVFSEFFQQGDLEREKLKEEPMAMMDRKKKDELPKMQVGFIDGICMPVYKMFAELWPDL 844
Query: 698 TPLRTGTADNRRRWQDLAE 716
PL +GT NR WQ L+E
Sbjct: 845 KPLESGTQLNRDNWQALSE 863
Score = 44.4 bits (100), Expect = 0.013
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 25/125 (20%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA++ +++NI + + R N +++CMPI N + +V+GVAQ+INK
Sbjct: 198 IAGHVAQTKETVNIKNAYEDKRFNPEVDKITGYKTHSIMCMPICNHDGEVVGVAQVINKI 257
Query: 346 ------------------------FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQ 381
F D +F+ + FCG+GI N Q++E + +
Sbjct: 258 TGSHEFAAKDEEAQVELRRIVSHEFNPADEEVFKNYLTFCGIGIMNAQLFEMSVNEYKRN 317
Query: 382 KVALE 386
++ L+
Sbjct: 318 QMLLQ 322
>UniRef50_Q9VJ79 Cluster: Dual 3',5'-cyclic-AMP and -GMP
phosphodiesterase 11; n=9; Eumetazoa|Rep: Dual
3',5'-cyclic-AMP and -GMP phosphodiesterase 11 -
Drosophila melanogaster (Fruit fly)
Length = 1451
Score = 553 bits (1366), Expect = e-156
Identities = 287/575 (49%), Positives = 369/575 (64%), Gaps = 26/575 (4%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
FS D +VF YL FCGIG++NAQL+E S LE KRNQ+LL LAR IFEEQS +E +V +I
Sbjct: 553 FSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRI 612
Query: 210 MTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXXXTRFH 269
+T + L++C+R V IL + R+ + +
Sbjct: 613 LTHMQSLIQCQR--VQILLVHEADKGSFSRVFDFEANDLSEEEATSRT--------SPYE 662
Query: 270 TVFELGAPRRPHDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGV-RTLLCMP 328
+ F + H VA + +++N+ + + R + S ENS R++LCM
Sbjct: 663 SRFPINIGITGH---------VATTGETVNVPNAYEDDRFD-ASVDENSCFKHRSILCMA 712
Query: 329 IVNANKDVIGVAQLINKF-----TEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKV 383
I N+ +IGV QLINKF T+ D + EAFAIFCG+GIHNT MYE A MAKQ V
Sbjct: 713 IKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSV 772
Query: 384 ALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCEL 443
LE LSYHA+A+ ++ +L + +PSA + L+ F+F D D+DT +A LRMFL +
Sbjct: 773 TLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDLDF 832
Query: 444 VEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILG 503
VE+FHI Y+VLCRW+LSVKKNYR V YHNWRHA NVAQ MFA+L T + + ++E L
Sbjct: 833 VERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLA 892
Query: 504 LLVACLCHDLDHRGTNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALS 563
L++ CLCHDLDHRGTNN+FQ K SPLA LYSTSTMEHHHFDQC+MILNS N I LS
Sbjct: 893 LIIGCLCHDLDHRGTNNSFQIKASSPLAQLYSTSTMEHHHFDQCLMILNSPGNQILANLS 952
Query: 564 PRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDV 623
DY V+ V+E AILSTDLA+YFKK+ FLE V W A+E + LL M MT CD+
Sbjct: 953 SDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDL 1012
Query: 624 SAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTIC 683
SAI KPWE++ R+A LV+ EFF+QGD+EK +LN PI +M+REK+DELP MQV FID+IC
Sbjct: 1013 SAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSIC 1072
Query: 684 LPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKV 718
LP+Y+ + + PL G DNR W DLA+ V
Sbjct: 1073 LPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADVV 1107
Score = 70.1 bits (164), Expect = 2e-10
Identities = 41/105 (39%), Positives = 60/105 (57%), Gaps = 5/105 (4%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA S + +NI D Q R N + LLCMPI +++ DVIGVAQ+INK
Sbjct: 489 IAGHVAESGEPVNIPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKM 548
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
F+E D +F ++ FCG+G+ N Q+YE + + + +V L+
Sbjct: 549 NGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLD 593
Score = 62.9 bits (146), Expect = 4e-08
Identities = 27/46 (58%), Positives = 37/46 (80%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
+FN EID+ TGY+T+ +LCMPI + GDV+GVAQ+INK +GE +E
Sbjct: 510 RFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNGECFSE 555
Score = 38.3 bits (85), Expect = 0.86
Identities = 16/38 (42%), Positives = 25/38 (65%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
+F++ +D + +K ILCM I N G ++GV Q+INK
Sbjct: 692 RFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINK 729
>UniRef50_Q7Q8G2 Cluster: ENSANGP00000013023; n=2; Diptera|Rep:
ENSANGP00000013023 - Anopheles gambiae str. PEST
Length = 747
Score = 536 bits (1322), Expect = e-150
Identities = 284/607 (46%), Positives = 380/607 (62%), Gaps = 52/607 (8%)
Query: 142 LSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSN 201
++ G + FS+ D ++F YL FCGIG++NAQL+E S LE KRNQ+LL LAR IFEEQS
Sbjct: 158 INKQGDQCFSTADEKIFSSYLQFCGIGLRNAQLYEKSQLEVKRNQVLLDLARMIFEEQST 217
Query: 202 LECLVTKIMTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXX 261
+E +V +I+T + L++C+R V IL R+
Sbjct: 218 IEHMVFRILTHMQSLIQCQR--VQILLVHEASKGSFSRVFDFEANDLSGEDGDART---- 271
Query: 262 XXXXTRFHTVFELGAPRRPHDALPAIALAVARSNKSLNISDVEQWLR-DNNMSAGENSAG 320
+ F + F + I VA + +++NI + + R D ++ G N
Sbjct: 272 ----SPFESRFPINV---------GITGYVATTGETVNICNAYEDDRFDPSVDEGLNFRH 318
Query: 321 VRTLLCMPIVNANKDVIGVAQLINKF-----TEGDVSIFEAFAIFCGLGIHNTQMYENAC 375
+T+LCM I N+ +IGV QLINKF T+ D + EAFAIFCG+GIHNT MYE A
Sbjct: 319 -KTILCMAIKNSLSQIIGVIQLINKFDDLTFTKNDENFVEAFAIFCGMGIHNTHMYEKAI 377
Query: 376 KLMAKQKVALECLSYHATASAEDTSKL-----------C-------------QDEIPSAE 411
MAKQ V LE LSYHA+A+ +D +L C Q ++PS+
Sbjct: 378 IAMAKQSVTLEVLSYHASATIDDAYRLRVTCTLRLEFVCFHKALTLIFNLLQQLKVPSSA 437
Query: 412 TYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYH 471
+ LY F+F D L D+ T +A LRMFL +LVE+FHI Y+VLCRW+LSVKKNYR V YH
Sbjct: 438 FFKLYDFKFDDLTLDDDHTLKACLRMFLDLDLVERFHIEYEVLCRWLLSVKKNYRNVTYH 497
Query: 472 NWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLA 531
NWRHA NV Q MFA+L + + + ++E L L++ACLCHDLDHRGTNN+FQ K SPLA
Sbjct: 498 NWRHAFNVTQMMFAILTSTQWWKIFGEIECLALIIACLCHDLDHRGTNNSFQIKASSPLA 557
Query: 532 ILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKS 591
LYSTSTMEHHHFDQC+MI+NS N I +S DY V+ V+E AILSTDLA+YF+K+
Sbjct: 558 QLYSTSTMEHHHFDQCLMIINSPGNQILSNMSSEDYSRVIRVLEDAILSTDLAVYFRKRG 617
Query: 592 KFLELVDNGE--FDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGD 649
FL LV+ WQA+E + LL M MT CD+SAI KPWE++ R+A LV+ EFF+QGD
Sbjct: 618 AFLNLVEPASEMSSWQAEEPRSLLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGD 677
Query: 650 LEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRR 709
+E+ +LN PI +M+REK+D+LP MQVGFID+IC+P+Y+ + +TPL G +N++
Sbjct: 678 MERQELNITPIDIMNREKEDQLPMMQVGFIDSICIPIYEAFATLSDKLTPLIDGVRENKQ 737
Query: 710 RWQDLAE 716
W +LA+
Sbjct: 738 HWIELAQ 744
Score = 72.5 bits (170), Expect = 4e-11
Identities = 41/105 (39%), Positives = 60/105 (57%), Gaps = 5/105 (4%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA S + +NI D Q R N + + LLCMPI +A+ DV+GVAQ+INK
Sbjct: 102 IAGHVAESGEPVNIPDAYQDERFNREIDVQTGYRTKALLCMPIKDASGDVVGVAQVINKQ 161
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
F+ D IF ++ FCG+G+ N Q+YE + + + +V L+
Sbjct: 162 GDQCFSTADEKIFSSYLQFCGIGLRNAQLYEKSQLEVKRNQVLLD 206
Score = 59.3 bits (137), Expect = 4e-07
Identities = 25/38 (65%), Positives = 32/38 (84%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
+FN EID +TGY+T+ +LCMPI + GDVVGVAQ+INK
Sbjct: 123 RFNREIDVQTGYRTKALLCMPIKDASGDVVGVAQVINK 160
Score = 36.3 bits (80), Expect = 3.5
Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLDHNY 107
+F+ +D ++ + ILCM I N ++GV Q+INK D T++ D N+
Sbjct: 305 RFDPSVDEGLNFRHKTILCMAIKNSLSQIIGVIQLINKFDDLTFTKN--DENF 355
>UniRef50_O76074 Cluster: cGMP-specific 3',5'-cyclic
phosphodiesterase; n=47; Euteleostomi|Rep: cGMP-specific
3',5'-cyclic phosphodiesterase - Homo sapiens (Human)
Length = 875
Score = 492 bits (1214), Expect = e-137
Identities = 258/584 (44%), Positives = 348/584 (59%), Gaps = 13/584 (2%)
Query: 138 LRRKLSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFE 197
+ +K + G+ F+ +D + F YL FCGI + NAQL+E+S+LE KRNQ+LL LA IFE
Sbjct: 285 INKKSGNGGT--FTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFE 342
Query: 198 EQSNLECLVTKIMTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXX 257
EQ +LE ++ KI ++ ++C +FI+D D C S
Sbjct: 343 EQQSLEVILKKIAATIISFMQVQKCTIFIVDED-CSDSFSSVFHMECEELEKSSDTLTRE 401
Query: 258 XXXXXXXXTRFHTVFELGAPRRPHDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGEN 317
V P D N N++ +Q +R + +N
Sbjct: 402 HDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTG-NVN--QQCIRSLLCTPIKN 458
Query: 318 SAGVRTLLCMPIVNANKDVIGVAQLINKFTEGDVSIFEAFAIFCGLGIHNTQMYENACKL 377
+ + +VN ++ G + F D EAF IFCGLGI NTQMYE +
Sbjct: 459 GKKNKVIGVCQLVNKMEENTG---KVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERA 515
Query: 378 MAKQKVALECLSYHATASAEDT---SKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRAT 434
MAKQ V LE LSYHA+A+ E+T L +PSA+T + F F DF+L+D +T T
Sbjct: 516 MAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCT 575
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNYRP-VKYHNWRHALNVAQTMFAMLKTGKME 493
+RMF LV+ F + ++VLCRWILSVKKNYR V YHNWRHA N AQ MFA LK GK++
Sbjct: 576 IRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQ 635
Query: 494 RFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNS 553
++DLEIL LL+A L HDLDHRG NN++ ++E PLA LY S MEHHHFDQC+MILNS
Sbjct: 636 NKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNS 695
Query: 554 ESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELL 613
N I LS +YK + +++ AIL+TDLA+Y K++ +F EL+ +F+ + +KEL
Sbjct: 696 PGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELF 755
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQ 673
M+MTACD+SAI KPW +Q RIA+LVA EFFDQGD E+ +LN +P +M+REKK+++P
Sbjct: 756 LAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNKIPS 815
Query: 674 MQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
MQVGFID ICL LY+ L+ PL G NR++WQ LAE+
Sbjct: 816 MQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQ 859
Score = 68.5 bits (160), Expect = 7e-10
Identities = 60/198 (30%), Positives = 92/198 (46%), Gaps = 15/198 (7%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----- 345
VA + LNI D + R N +++LCMPI N ++V+GVAQ INK
Sbjct: 233 VAALGEPLNIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNG 292
Query: 346 --FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLC 403
FTE D F A+ FCG+ +HN Q+YE + + +V L+ S + + ++
Sbjct: 293 GTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLAS--LIFEEQQSLEVI 350
Query: 404 QDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMF-LQCELVEKFHIPYDVLCRWILSVK 462
+I +A + Q + DED + +F ++CE +EK D L R + K
Sbjct: 351 LKKI-AATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEK---SSDTLTREHDANK 406
Query: 463 KNYRPVKY-HNWRHALNV 479
NY +Y N LN+
Sbjct: 407 INYMYAQYVKNTMEPLNI 424
Score = 59.7 bits (138), Expect = 3e-07
Identities = 28/50 (56%), Positives = 35/50 (70%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLD 104
+FN+E+D TGYKT+ ILCMPI N+ +VVGVAQ INK G T + D
Sbjct: 250 RFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKD 299
>UniRef50_Q4SVG8 Cluster: Chromosome undetermined SCAF13758, whole
genome shotgun sequence; n=4; Tetraodontidae|Rep:
Chromosome undetermined SCAF13758, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 928
Score = 465 bits (1146), Expect = e-129
Identities = 229/448 (51%), Positives = 310/448 (69%), Gaps = 16/448 (3%)
Query: 291 VARSNKSLNISDV--EQWLRDNNMSAGENSAGVRTLLCMPIVNANKD-VIGVAQLINKFT 347
V + ++LNI+DV +Q +A ++ +++LLC PI N KD VIGV QL+NK
Sbjct: 477 VKNTMQTLNIADVSKDQRFPWTGENADVSNDQIKSLLCTPIRNGKKDKVIGVCQLVNKMD 536
Query: 348 EGD-VSIF--------EAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAED 398
E D V F EAFAIFCGLGI NTQMYE + MAKQ+V LE LSYHATAS E+
Sbjct: 537 EADSVKTFNRNDEQFLEAFAIFCGLGIQNTQMYERVERAMAKQEVTLEVLSYHATASEEE 596
Query: 399 TSKL---CQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLC 455
+ +L +PSA++ +L F F DF+L+D +T AT+RMF+ +LV+ F + Y LC
Sbjct: 597 SRELQVTVGATVPSAQSLSLLDFSFSDFELSDMETTLATVRMFVDLDLVQNFQMKYTNLC 656
Query: 456 RWILSVKKNYRP-VKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLD 514
RW+LS+KKNYR V YHNWRHA N AQ+MFA+LK+G+++ ++DLE+L L++A L HDLD
Sbjct: 657 RWVLSIKKNYRKSVAYHNWRHAFNTAQSMFALLKSGRLQNELTDLEVLALMIATLSHDLD 716
Query: 515 HRGTNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVV 574
HRG NN++ ++E PLA LY STMEHHHFD C+MILNS N I LS +YK + ++
Sbjct: 717 HRGVNNSYIQRSEHPLAQLYCHSTMEHHHFDHCLMILNSPGNQILSGLSLDEYKSTLKMI 776
Query: 575 ETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQH 634
E AIL+TDLA++ K++ +F EL N +F W+ + ++LL M+MTACD+SAI KPW VQ
Sbjct: 777 ERAILATDLALHMKRRGEFFELTKNSQFRWEDEGHRDLLRSMLMTACDISAITKPWPVQQ 836
Query: 635 RIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTF 694
RIA+LVA EFF+QGD E+ +LN +P +M+REKKD++P MQV FID IC LY+ L+
Sbjct: 837 RIAELVATEFFEQGDKERRELNIEPSDLMNREKKDKIPSMQVSFIDAICTQLYQTLAGMS 896
Query: 695 PWMTPLRTGTADNRRRWQDLAEKVDMGL 722
+ +PL G NR +W+ LAE+ + GL
Sbjct: 897 EYCSPLLEGCRKNREQWKHLAEECEEGL 924
Score = 57.2 bits (132), Expect = 2e-06
Identities = 28/48 (58%), Positives = 35/48 (72%), Gaps = 2/48 (4%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK--TDGE 96
Y +FN+E+D TGYKT+ ILC+PI N +VVGVAQ INK +DGE
Sbjct: 223 YQDSRFNAEVDLITGYKTQSILCLPIKNQRDEVVGVAQAINKKSSDGE 270
Score = 38.3 bits (85), Expect = 0.86
Identities = 19/49 (38%), Positives = 26/49 (53%)
Query: 186 QILLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILDTDHCES 234
Q+LL LA +F+EQ LE L+ K ++ + C VFI D D S
Sbjct: 393 QVLLDLASLLFQEQQCLEVLLRKFAGTILSFMQAQACTVFIADPDSMNS 441
Score = 37.9 bits (84), Expect = 1.1
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLIN-KFTEG 349
VA + + LNI + Q R N +++LC+PI N +V+GVAQ IN K ++G
Sbjct: 210 VAATGQPLNIRNAYQDSRFNAEVDLITGYKTQSILCLPIKNQRDEVVGVAQAINKKSSDG 269
Query: 350 DVSIFE 355
+ + E
Sbjct: 270 EAAFTE 275
Score = 35.9 bits (79), Expect = 4.6
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 138 LRRKLSHSGS-KEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLAL----A 192
L K+ + S K F+ D + + FCG+GIQN Q++E + ++ L + A
Sbjct: 531 LVNKMDEADSVKTFNRNDEQFLEAFAIFCGLGIQNTQMYERVERAMAKQEVTLEVLSYHA 590
Query: 193 RSIFEEQSNLECLVTKIMTEARDL 216
+ EE L+ V + A+ L
Sbjct: 591 TASEEESRELQVTVGATVPSAQSL 614
>UniRef50_Q9HCR9 Cluster: Dual 3',5'-cyclic-AMP and -GMP
phosphodiesterase 11A; n=42; Eumetazoa|Rep: Dual
3',5'-cyclic-AMP and -GMP phosphodiesterase 11A - Homo
sapiens (Human)
Length = 934
Score = 450 bits (1109), Expect = e-125
Identities = 242/580 (41%), Positives = 339/580 (58%), Gaps = 31/580 (5%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F+ D +V + YL FCGI I NAQ L A +R +E L +V +
Sbjct: 351 FTEDDEKVMQMYLPFCGIAISNAQ--------------LFAASRKEYERSRALLEVVNDL 396
Query: 210 MTEARDLLKCERC----AVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXXX 265
E DL K + A +L + C LE I
Sbjct: 397 FEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDI--ESPVVKFTKSFELMSPKCSADAE 454
Query: 266 TRFHTVFELGAPRRPHDAL--PAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRT 323
F E + D L +IA VA + +NISD Q R + + + +R+
Sbjct: 455 NSFKESMEKSSYS---DWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRS 511
Query: 324 LLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLM 378
+LC+PI N+N +IGVAQ++N+ F + D +FEAF IFCGLGI+NT MY+ K
Sbjct: 512 VLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSW 571
Query: 379 AKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMF 438
AKQ VAL+ LSYHAT S + K IP + F DF L + A LRMF
Sbjct: 572 AKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMF 631
Query: 439 LQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSD 498
++ +V+KF I Y+ LCRW+L+V+KNYR V YHNWRHA NV Q MFAML T + +++
Sbjct: 632 MELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTE 691
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTS-TMEHHHFDQCVMILNSESNN 557
+EIL ++V CLCHDLDHRGTNNAFQ K+ S LA LY TS T+EHHHF+ VMIL SE +N
Sbjct: 692 VEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHN 751
Query: 558 IFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMM 617
IF LS ++Y D+M +++ +IL+TDL +YF+++++F ELV GE+DW + +++ M+
Sbjct: 752 IFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSML 811
Query: 618 MTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVG 677
MTACD+ A+ KPWE+ ++A+LV EFF+QGD E+L+L P A+ DR +KDELP++Q+
Sbjct: 812 MTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLE 871
Query: 678 FIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
+ID+IC+PLY+ L + P+ A NR +W++L +K
Sbjct: 872 WIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQK 911
Score = 60.1 bits (139), Expect = 2e-07
Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 6/105 (5%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----- 345
V +++NI D Q R N+ ++LLCMPI +++ ++IGVAQ INK
Sbjct: 290 VGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGA 349
Query: 346 -FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLS 389
FTE D + + + FCG+ I N Q++ + K + + LE ++
Sbjct: 350 PFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVN 394
Score = 56.0 bits (129), Expect = 4e-06
Identities = 26/47 (55%), Positives = 35/47 (74%), Gaps = 1/47 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK-TDGEHTTE 100
+FN EID TGYKT+ +LCMPI + +G+++GVAQ INK +G TE
Sbjct: 307 RFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTE 353
Score = 44.0 bits (99), Expect = 0.017
Identities = 16/42 (38%), Positives = 29/42 (69%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
+F++E D +G+ +LC+PI N ++GVAQ++N+ DG+
Sbjct: 496 RFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGK 537
>UniRef50_UPI0000D8B81A Cluster: UPI0000D8B81A related cluster; n=1;
Mus musculus|Rep: UPI0000D8B81A UniRef100 entry - Mus
musculus
Length = 746
Score = 393 bits (968), Expect = e-108
Identities = 199/424 (46%), Positives = 276/424 (65%), Gaps = 30/424 (7%)
Query: 321 VRTLLCMPIVNANKDVI-GVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENA 374
+R++LC+PI N+N +I GVAQ++N+ F + D +FEAF IFCGLGI+NT MY+
Sbjct: 323 IRSVLCVPIWNSNHQIIAGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQV 382
Query: 375 CKLMAKQKVALECLSYHATASAEDTSKL-------C----QDE------IPSAETYNLYS 417
K AKQ VAL+ LSYHAT S + K C Q E IP +
Sbjct: 383 KKSWAKQSVALDVLSYHATCSKAEVDKFKVRKRWSCTVSTQRERVYAANIPLVSELAIDD 442
Query: 418 FQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHAL 477
F DF L + A LRMF++ +V+KF I Y+ LCRW+L+V+KNYR V YHNWRHA
Sbjct: 443 IHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAF 502
Query: 478 NVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTS 537
NV Q MFAML T + ++++EIL ++V CLCHDLDHRGTNNAFQ K++S LA LY TS
Sbjct: 503 NVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTS 562
Query: 538 -TMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLEL 596
T+EHHHF+ VMIL SE +NIF LS ++Y D+M +++ +IL+TDL +YF +K F +
Sbjct: 563 ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFDEKILFSRI 622
Query: 597 V-----DNGEFD-WQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDL 650
+ +GE + ++ LL M+MTACD+ A+ KPWE+ ++A+LV EFF+QGD
Sbjct: 623 ILQCPLHDGEAEPGHYKQCDPLLRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDR 682
Query: 651 EKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRR 710
E+ +L P A+ DR +KDELP++Q+ +ID+IC+PLY+ L + P+ A NRR+
Sbjct: 683 ERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRK 742
Query: 711 WQDL 714
W++L
Sbjct: 743 WEEL 746
Score = 58.4 bits (135), Expect = 8e-07
Identities = 27/47 (57%), Positives = 35/47 (74%), Gaps = 1/47 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKT-DGEHTTE 100
+FN EID TGYKT+ +LCMPI N +G+++GVAQ INK +G TE
Sbjct: 107 RFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTE 153
Score = 51.6 bits (118), Expect = 9e-05
Identities = 23/43 (53%), Positives = 32/43 (74%)
Query: 186 QILLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILD 228
Q LL + +FEEQ++LE +V KIM A+ LLKCERC+V +L+
Sbjct: 183 QALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLE 225
Score = 45.2 bits (102), Expect = 0.008
Identities = 24/59 (40%), Positives = 34/59 (57%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINKFTEG 349
V +++NI D Q R N+ ++LLCMPI N++ ++IGVAQ INK EG
Sbjct: 90 VGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEG 148
Score = 37.5 bits (83), Expect = 1.5
Identities = 18/48 (37%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Query: 50 KYITIQFNSEIDARTGYKTELILCMPICNYEGDVV-GVAQIINKTDGE 96
K I I N+ D +G+ +LC+PI N ++ GVAQ++N+ DG+
Sbjct: 305 KDIYIFQNTRADQISGFHIRSVLCVPIWNSNHQIIAGVAQVLNRLDGK 352
>UniRef50_P16499 Cluster: Rod cGMP-specific 3',5'-cyclic
phosphodiesterase subunit alpha; n=90; Vertebrata|Rep:
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit
alpha - Homo sapiens (Human)
Length = 860
Score = 378 bits (929), Expect = e-103
Identities = 215/615 (34%), Positives = 335/615 (54%), Gaps = 45/615 (7%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F+ RD E+ +YL F + ++ L E +R QILL +FEE +++E K
Sbjct: 203 FTKRDEEILLKYLNFANLIMKWYHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKA 262
Query: 210 MTEARDLLKCERCAVFILD-TDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXXXTRF 268
+ R L C+R +V +LD T E + ++
Sbjct: 263 LYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEVPPYSGPRTPDGREINFYKVIDYI 322
Query: 269 -HTVFELGA-PRRPHD---ALPAIALAVARSNKSLNISDV--EQWLRDNNMSAGENSAGV 321
H ++ P P D + + VA++ NI + E + E+ +
Sbjct: 323 LHGKEDIKVIPNPPPDHWALVSGLPAYVAQNGLICNIMNAPAEDFFAFQKEPLDESGWMI 382
Query: 322 RTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACK 376
+ +L MPIVN ++++GVA N+ F E D ++ E+ F G + N YE+ K
Sbjct: 383 KNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLTQFLGWSVLNPDTYESMNK 442
Query: 377 LMAKQKVALECLSYHATASAEDTSKL-------------CQD---------EIPSAETYN 414
L ++ + + + YH E+ K+ C++ E+P A+ Y
Sbjct: 443 LENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPWECEEEELAEILQAELPDADKYE 502
Query: 415 LYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWR 474
+ F F D LT+ + + ++M+ + ++V+KFHIP + L R++ S+ K YR + YHNWR
Sbjct: 503 INKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRKITYHNWR 562
Query: 475 HALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY 534
H NV QTMF++L TGK++R+ +DLE L ++ A CHD+DHRGTNN +Q K+++PLA L+
Sbjct: 563 HGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLH 622
Query: 535 STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFL 594
+S +E HH + +L ES NIFQ L+ R ++ +H+++ AI++TDLA+YFKK++ F
Sbjct: 623 GSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQ 682
Query: 595 ELVD-----NGEFDWQ-----AQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEF 644
++VD E +W Q +KE++ MMMTACD+SAI KPWEVQ ++A LVA EF
Sbjct: 683 KIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACDLSAITKPWEVQSQVALLVAAEF 742
Query: 645 FDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGT 704
++QGDLE+ L Q PI MMDR K DELP++QVGFID +C +YK S +TP+ G
Sbjct: 743 WEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGI 802
Query: 705 ADNRRRWQDLAEKVD 719
+NR+ W+ LA++ D
Sbjct: 803 TNNRKEWKALADEYD 817
Score = 41.9 bits (94), Expect = 0.070
Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 60 IDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLDHNYEPRPGQITRGPV 119
+D T YKT+ IL PI N + DVV + +NK DG H T+ + E + +
Sbjct: 166 VDILTEYKTKNILASPIMNGK-DVVAIIMAVNKVDGSHFTK----RDEEILLKYLNFANL 220
Query: 120 ASHWYSLYYFGNQRLYTYLRRKLSHSGSKEFSS-RDVE 156
WY L Y N T + L SGSK F D+E
Sbjct: 221 IMKWYHLSYLHN--CETRRGQILLWSGSKVFEELTDIE 256
>UniRef50_Q16HU8 Cluster: Camp and camp-inhibited cgmp 3,5-cyclic
phosphodiesterase; n=5; Eumetazoa|Rep: Camp and
camp-inhibited cgmp 3,5-cyclic phosphodiesterase - Aedes
aegypti (Yellowfever mosquito)
Length = 767
Score = 359 bits (882), Expect = 2e-97
Identities = 209/570 (36%), Positives = 306/570 (53%), Gaps = 27/570 (4%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F D E+ YL + GI I A L + + K N LLA+ +SIF++ +++ LV+K+
Sbjct: 210 FYEEDEEIGCSYLVWGGIAIHYAHLNLVGLKQRKLNDFLLAVVKSIFQDMVSMDMLVSKV 269
Query: 210 MTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXXXTRFH 269
M A+ L+ +R ++F++D+ +S L + RF
Sbjct: 270 MNFAQRLVDADRASLFLVDS---KSKELYATIFDVGCDEKTAMNENENELNKAPKEIRF- 325
Query: 270 TVFELGAPRRPHDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPI 329
LG IA VA + + LNI D R N ++LCMPI
Sbjct: 326 ---PLGT---------GIAGQVAMTGEILNIVDAYADSRFNRTIDQITGYKTESILCMPI 373
Query: 330 VNANKDVIGVAQLINK----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVAL 385
++IGV Q++NK F++ D FE FA++CGL +H+ ++Y+ + K +VAL
Sbjct: 374 F-IRGNIIGVVQMVNKRSGYFSKEDEEAFEMFAVYCGLALHHAKLYDKIRRSEQKYRVAL 432
Query: 386 ECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVE 445
E LSYH T S + + IP + + S+ F F + +D +A +F+ +L
Sbjct: 433 EVLSYHNTCSESEVEHCLVEGIP-LKIPGIDSYDFSPFVI--DDFQKAIYSVFMFKDLFG 489
Query: 446 KFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLL 505
L R+ L+VKKNYR V YHNW H +VA TM++++K E L L
Sbjct: 490 LSRFDKTSLIRFTLTVKKNYRRVPYHNWTHGFSVANTMYSIIKN--CPHVFRPNECLALF 547
Query: 506 VACLCHDLDHRGTNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPR 565
+ LCHDLDHRG NN F TESPLA +YSTSTMEHHHF+Q V IL E +NIF L+
Sbjct: 548 IGSLCHDLDHRGKNNKFMLDTESPLAAIYSTSTMEHHHFNQTVTILQQEGHNIFSKLNSN 607
Query: 566 DYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSA 625
+YK V+ +++ IL+TDLA++F K K +LVDN +F W E + L+ + MT D+SA
Sbjct: 608 EYKQVLSLIKHCILATDLALFFPNKDKLSKLVDNEQFSWTVAEHRMLIQTIAMTGADLSA 667
Query: 626 IAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLP 685
AKPW VQ K++ EF+DQGD EK + +QPIAMMDR++ ++ Q+GF++ IC+P
Sbjct: 668 SAKPWAVQTETVKVIFAEFYDQGDEEK-KAGRQPIAMMDRDQPEQQAASQLGFLNGICIP 726
Query: 686 LYKVLSDTFPWMTPLRTGTADNRRRWQDLA 715
Y +L P P+ T +N RWQ ++
Sbjct: 727 CYTLLHRLIPETKPMLTMCNENLERWQQIS 756
Score = 52.4 bits (120), Expect = 5e-05
Identities = 25/50 (50%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
Y +FN ID TGYKTE ILCMPI G+++GV Q++NK G + E
Sbjct: 348 YADSRFNRTIDQITGYKTESILCMPIF-IRGNIIGVVQMVNKRSGYFSKE 396
>UniRef50_UPI0000F1D4E2 Cluster: PREDICTED: similar to
Phosphodiesterase 5A; n=4; Danio rerio|Rep: PREDICTED:
similar to Phosphodiesterase 5A - Danio rerio
Length = 905
Score = 346 bits (850), Expect = 2e-93
Identities = 175/407 (42%), Positives = 252/407 (61%), Gaps = 28/407 (6%)
Query: 321 VRTLLCMPIVNA-NKDVIGVAQLINK---------FTEGDVSIFEAFAIFCGLGIHNTQM 370
+R+L+ P+ + +VIGV QL+NK F+ D + E FA++C LG+
Sbjct: 504 IRSLIGAPLRGKQSSNVIGVCQLVNKRMAIAESEAFSRADEHLLEDFAVYCALGLQKFNT 563
Query: 371 YENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDT 430
+ A K + V E + IPSA+T +L F F DFD++
Sbjct: 564 QQTADKTRVRLAVTKE-----------------EAAIPSADTLSLLDFGFSDFDMSQNAM 606
Query: 431 CRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRP-VKYHNWRHALNVAQTMFAMLKT 489
+A +RMFL L ++F I Y LC+W+LSV+K YR V YHNW HAL AQ MFAML+T
Sbjct: 607 TQAVVRMFLDLNLPQEFKIDYKALCQWVLSVQKCYRSNVVYHNWSHALRTAQCMFAMLQT 666
Query: 490 GKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTSTMEHHHFDQCVM 549
+++ +S LE+L L++A L HDLDHRG NN++ ++ PLA LY S++EHHH+D C++
Sbjct: 667 KELKSNLSSLEVLALMIASLSHDLDHRGVNNSYIQRSNQPLAQLYGQSSLEHHHYDMCLL 726
Query: 550 ILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEK 609
ILN+ + I +LS +Y + ++E IL+TDLA++F+K++KF +L +N W+ +
Sbjct: 727 ILNNPGSQILSSLSVNEYMACLQMIEKNILATDLAIFFEKRTKFFKLAENNSCLWKDEGH 786
Query: 610 KELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKD 669
+ELL M+MTA D+ AI KPW VQ RIA+LVA EF+ QGD EK +LN QPI +MDRE
Sbjct: 787 RELLRSMLMTASDICAITKPWPVQKRIAELVATEFYAQGDREKRELNIQPIDVMDRENAS 846
Query: 670 ELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAE 716
LPQMQV +ID IC PLY+ L+ +PL+ G + NR+ WQ++ +
Sbjct: 847 RLPQMQVDYIDGICSPLYEALAFICESCSPLKEGCSKNRKHWQEMVD 893
Score = 53.6 bits (123), Expect = 2e-05
Identities = 27/82 (32%), Positives = 47/82 (57%)
Query: 147 SKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLV 206
S FS +D +V ++ G+ ++N QL ESS E KRNQ+LL LA+ + + +++ ++
Sbjct: 361 SSFFSEQDEKVLSSHMMLFGLILENHQLCESSEQENKRNQVLLELAQLVSHDYPSVDAML 420
Query: 207 TKIMTEARDLLKCERCAVFILD 228
++ + K + C VFI D
Sbjct: 421 GELAAVILPITKAQFCTVFISD 442
Score = 37.5 bits (83), Expect = 1.5
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 10/105 (9%)
Query: 291 VARSNKSLNISDVEQWLRDN-NMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK---- 345
V R+ + L + D + R + GE ++L +P++N K+VIGV +NK
Sbjct: 301 VVRTGRPLTVKDAHEDPRFQVELYEGEEDRPT-SVLSVPVLNHKKEVIGVVLAVNKTRTC 359
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
F+E D + + + GL + N Q+ E++ + + +V LE
Sbjct: 360 ASSFFSEQDEKVLSSHMMLFGLILENHQLCESSEQENKRNQVLLE 404
>UniRef50_Q4RHZ1 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15044, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 884
Score = 328 bits (806), Expect = 4e-88
Identities = 220/597 (36%), Positives = 314/597 (52%), Gaps = 50/597 (8%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQS--NLECLVT 207
F+ D +V + YL FCGI I NA+LF S EY+R+++ + +++S N +VT
Sbjct: 305 FTEDDEKVLQMYLPFCGISISNAKLFSESRKEYERSRVRGGIRTFPGKQESGSNQRFVVT 364
Query: 208 KIMTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXXXTR 267
+ + E + L F TD + +I+Q +
Sbjct: 365 QALLEVVNDL-------FEEQTDL--EKIVRKIMQRALTLLQCERCSVLLLEDIDSPVVK 415
Query: 268 FHTVFELGAPRRPHDA--------------LPAIALAVARSNKSLNISDVEQWLRDNNMS 313
F FEL +P D +IA VA + +NISDV Q R + +
Sbjct: 416 FSKTFELMSPLCNMDRDISMEKLSCSDWLINNSIAELVASTGLPVNISDVCQDPRFDAEA 475
Query: 314 AGENSAGVRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNT 368
+ +R++LC+PI N +IGVAQ++N+ F + D +FEAF IFCGLGI+NT
Sbjct: 476 DQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNT 535
Query: 369 QMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDE 428
MY K AKQ VAL+ LSYHAT S + +L +IP + + F F+DF L ++
Sbjct: 536 MMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSGELGIEEFHFNDFSLDND 595
Query: 429 DTCRATLRMFLQCELVEKFHIPYDV-------LCRWILSVKKNYRPVKYHNWRHALNVAQ 481
A+LRMFL+ +V+KF I Y+V LCRW+L+V+KNYR V YHNWRHA NV+Q
Sbjct: 596 AMITASLRMFLELGVVQKFKIDYEVRGQPRKVLCRWLLTVRKNYRTVAYHNWRHAFNVSQ 655
Query: 482 TMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTS-TME 540
MF M+ T + +SD E+L L+V CLCHDLDHRGTNNAFQ KT S LA+LY TS T+E
Sbjct: 656 CMFIMITTASFQDVLSDAEVLALMVGCLCHDLDHRGTNNAFQAKTGSALALLYGTSATLE 715
Query: 541 HHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNG 600
HHHF+ VMIL SE + + +V H ++ + +K + ELV +
Sbjct: 716 HHHFNHAVMILQSE-----VGVDQNELVEV-HADDSGCDLGAVTRPWKISKQVAELVTSE 769
Query: 601 EFDWQAQEKKELLC--GMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEK-LQLNQ 657
F+ +E+ EL + V+A A + + + + ++ D D+ K L+
Sbjct: 770 FFEQGDRERAELKLTPAVSKKVLSVTAFAVLLK-KIFVVSIGRNDTKDPLDVTKGSPLSL 828
Query: 658 QPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDL 714
QPI DR +KDELP +Q+ +ID IC PLY+ L + P+ NR +WQDL
Sbjct: 829 QPI--FDRNRKDELPALQLEWIDGICKPLYQTLLKLNRKLQPMADEIDANRNKWQDL 883
Score = 56.4 bits (130), Expect = 3e-06
Identities = 23/39 (58%), Positives = 31/39 (79%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKT 93
+F+ EID TGYKT+ ILC+ ICN +G+V+GV Q INK+
Sbjct: 261 RFSDEIDKLTGYKTQSILCLAICNSDGEVIGVVQAINKS 299
Score = 49.6 bits (113), Expect = 3e-04
Identities = 28/99 (28%), Positives = 52/99 (52%), Gaps = 6/99 (6%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----- 345
VA +++NI + + R ++ +++LC+ I N++ +VIGV Q INK
Sbjct: 244 VAEHGETVNIPNAYEDHRFSDEIDKLTGYKTQSILCLAICNSDGEVIGVVQAINKSPMGT 303
Query: 346 -FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKV 383
FTE D + + + FCG+ I N +++ + K + +V
Sbjct: 304 PFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYERSRV 342
Score = 41.9 bits (94), Expect = 0.070
Identities = 16/40 (40%), Positives = 27/40 (67%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
+F++E D +G+ +LC+PI N ++GVAQI+N+ D
Sbjct: 470 RFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLD 509
>UniRef50_Q9Y233 Cluster: cAMP and cAMP-inhibited cGMP 3',5'-cyclic
phosphodiesterase 10A; n=44; Euteleostomi|Rep: cAMP and
cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A -
Homo sapiens (Human)
Length = 779
Score = 317 bits (779), Expect = 7e-85
Identities = 173/449 (38%), Positives = 250/449 (55%), Gaps = 13/449 (2%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VAR+ + LNI D R N R +LCMPIV+ VIGV Q++NK
Sbjct: 330 IAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGS-VIGVVQMVNKI 388
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSK 401
F++ D + F+ FA+FC L +H MY +V +E LSYH+ ++E+
Sbjct: 389 SGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQG 448
Query: 402 LCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSV 461
L Q +P + F F D+ + + +++ + LCR+I+SV
Sbjct: 449 LMQFTLPVRLCKEIELFHF---DIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSV 505
Query: 462 KKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNA 521
KKNYR V YHNW+HA+ VA M+A+L+ +DLE GLL+ACLCHDLDHRG +N+
Sbjct: 506 KKNYRRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLERKGLLIACLCHDLDHRGFSNS 563
Query: 522 FQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILST 581
+ K + PLA LYSTSTME HHF Q V IL E +NIF LS +Y+ V+ ++ AI++T
Sbjct: 564 YLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIAT 623
Query: 582 DLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVA 641
DLA+YF + + E+ G + Q ++ + G+MMTACD+ ++ K W V A +
Sbjct: 624 DLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIY 683
Query: 642 DEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLR 701
EF+ +GD E +L QPI MMDR+KKDE+PQ Q+GF + + +P Y L+ P PL
Sbjct: 684 AEFWAEGD-EMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLL 742
Query: 702 TGTADNRRRWQDLAEKVDMGLTWIDHDTI 730
DN +W+ + + TWI ++
Sbjct: 743 KACRDNLSQWEKVIRGEETA-TWISSPSV 770
Score = 50.4 bits (115), Expect = 2e-04
Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLDHNYE 108
Y +FN E+D TGY T ILCMPI + G V+GV Q++NK G T ++N++
Sbjct: 347 YADPRFNREVDLYTGYTTRNILCMPIVS-RGSVIGVVQMVNKISGS-AFSKTDENNFK 402
Score = 42.7 bits (96), Expect = 0.040
Identities = 22/85 (25%), Positives = 42/85 (49%)
Query: 144 HSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLE 203
H G + F EV L + + I Q+ + + N LL ++++ F+ ++
Sbjct: 209 HWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAID 268
Query: 204 CLVTKIMTEARDLLKCERCAVFILD 228
L+ IM A++L+ +RCA+F +D
Sbjct: 269 SLLEHIMIYAKNLVNADRCALFQVD 293
Score = 37.9 bits (84), Expect = 1.1
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 9/110 (8%)
Query: 277 PRRPHDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDV 336
P P ++ VA+S K+L + D+ R + E+ ++++LC+PIV A D+
Sbjct: 141 PAGPITQGTTVSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDL 200
Query: 337 IGVAQLI-----NKFTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQ 381
IG+ +L F + A + + IH Q+ C+ +AKQ
Sbjct: 201 IGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQV----CRGLAKQ 246
>UniRef50_UPI000065DEB3 Cluster: Dual 3',5'-cyclic-AMP and -GMP
phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP
and cGMP phosphodiesterase 11A).; n=1; Takifugu
rubripes|Rep: Dual 3',5'-cyclic-AMP and -GMP
phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP
and cGMP phosphodiesterase 11A). - Takifugu rubripes
Length = 937
Score = 307 bits (753), Expect = 1e-81
Identities = 188/480 (39%), Positives = 268/480 (55%), Gaps = 53/480 (11%)
Query: 286 AIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK 345
+IA VA + +NISDV Q R + + + +R++LC+PI N +IGVAQ++N+
Sbjct: 460 SIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNR 519
Query: 346 -----FTEGDVSIFE-------------------AFAIFCGLGIHNTQMYENACKLMAKQ 381
F + D +FE AF IFCGLGI+NT MY K AKQ
Sbjct: 520 LDRKTFNDADQRLFEEIHVILKHNCYFLCLFLSQAFVIFCGLGINNTMMYNQVKKTWAKQ 579
Query: 382 KVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQC 441
VAL+ LSYHAT S + +L +IP + + F F+DF L ++ A+LRMFL+
Sbjct: 580 SVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDEFHFNDFSLDNDAMITASLRMFLEL 639
Query: 442 ELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRH---------------ALNVAQTMFAM 486
+V+KF I Y+VLCRW+L+V+KNYR V YHNWRH AL V +
Sbjct: 640 GVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHLQCFTVHVHNDYKILALMVGCLCHDL 699
Query: 487 LKTGKMERFMSDL--EILGLLVACLCHDLDHRGTNNAF-QTKTESPLAILYSTS-TMEHH 542
G F + E G+ A CH + + N+ F ++T S LA+LY TS T+EHH
Sbjct: 700 DHRGTNNAFQAKCVSEAWGM-TANWCHISEAKKPNSLFPSSRTGSALALLYGTSATLEHH 758
Query: 543 HFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEF 602
HF+ VMIL SE +NIF L ++Y ++M +++ AILSTDL ++F++++KF E V +GEF
Sbjct: 759 HFNHAVMILQSEGHNIFANLCSKEYSNMMQLLKQAILSTDLTLHFERRTKFFESVLSGEF 818
Query: 603 DWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLV-----ADEFFDQGDLEKLQLNQ 657
W + +E+ M+MTACD+ A+ +PW++ R LV ++ F GD E + N
Sbjct: 819 KWTDEGHREVFRSMLMTACDLGAVTRPWKISKRSGALVGIQISSNSSFWPGD-ETVCRNL 877
Query: 658 ---QPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDL 714
P + DR +KDELP +Q+ +ID IC PLYK L + P+ NR +WQDL
Sbjct: 878 IIFSPQPIFDRNRKDELPDLQLEWIDGICKPLYKTLLKLNRKLQPMVDEMDANRNKWQDL 937
Score = 56.0 bits (129), Expect = 4e-06
Identities = 23/38 (60%), Positives = 30/38 (78%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
+F+ EID TGYKT+ ILC+ ICN +G+V+GV Q INK
Sbjct: 188 RFSDEIDKLTGYKTQSILCLAICNSDGEVIGVVQAINK 225
Score = 54.0 bits (124), Expect = 2e-05
Identities = 38/100 (38%), Positives = 51/100 (51%), Gaps = 27/100 (27%)
Query: 156 EVFRRYLTFCGIGIQNAQLFESSVLEY------------------KRNQ---------IL 188
+V + YL FCGI I NA+LF S EY +R Q L
Sbjct: 320 QVLQMYLPFCGISISNAKLFSESRKEYERSRVRDRTSVFTRKQALRREQHFYNASLWSAL 379
Query: 189 LALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILD 228
L + +FEEQ++LE +V KIM A LL+CERC+V +L+
Sbjct: 380 LEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLE 419
Score = 41.9 bits (94), Expect = 0.070
Identities = 16/40 (40%), Positives = 27/40 (67%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
+F++E D +G+ +LC+PI N ++GVAQI+N+ D
Sbjct: 482 RFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLD 521
>UniRef50_P91119 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-5; n=3; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-5 - Caenorhabditis elegans
Length = 710
Score = 305 bits (748), Expect = 4e-81
Identities = 162/398 (40%), Positives = 237/398 (59%), Gaps = 10/398 (2%)
Query: 282 DALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQ 341
D IA VA + + LNI + + R N + +T+LCMPI+ VIGV Q
Sbjct: 295 DMSKGIAGYVASTGEGLNIENAYEDERFNADVDSKTGYTTKTILCMPIL-IRGIVIGVVQ 353
Query: 342 LINK----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAE 397
++NK FT D FE FA++CGL +H+ ++Y+ + K +VALE L+YH+ +A+
Sbjct: 354 MVNKHDGVFTRQDEDAFEIFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNAD 413
Query: 398 DTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRW 457
+ +KL + EI + L + F+ L++ + + MF + + + L R+
Sbjct: 414 EVNKLKKIEINN-RIVELETIDFNGMRLSELEKPLYAVYMF-KTLFADTLRFDTEDLIRF 471
Query: 458 ILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRG 517
+L+V+KNYR V YHNW H +VA MFA L + F + LE L L V+CLCHDLDHRG
Sbjct: 472 VLTVRKNYRRVAYHNWAHGWSVAHAMFATLMNSP-DAF-TKLEALALYVSCLCHDLDHRG 529
Query: 518 TNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETA 577
NNA+ +PLA +YSTS ME HHF+Q V IL + +NI ++LS DYK + +++
Sbjct: 530 KNNAYMKTMSTPLASIYSTSVMERHHFNQTVTILQQDGHNILKSLSSEDYKKTLSLIKHC 589
Query: 578 ILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIA 637
IL+TDLA++F K+K ++DN FD QE + L +MMT CD+ A AKPW +Q
Sbjct: 590 ILATDLALFFSNKAKLNVILDNNTFDINRQEHRLLTQAVMMTGCDLVASAKPWNIQTETV 649
Query: 638 KLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQ 675
K++ +EF+DQGD E+L ++PI MMDR++ LPQMQ
Sbjct: 650 KVIFEEFYDQGDAERLS-GKEPIPMMDRQQAHMLPQMQ 686
Score = 53.6 bits (123), Expect = 2e-05
Identities = 23/46 (50%), Positives = 34/46 (73%), Gaps = 1/46 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
+FN+++D++TGY T+ ILCMPI G V+GV Q++NK DG T +
Sbjct: 321 RFNADVDSKTGYTTKTILCMPIL-IRGIVIGVVQMVNKHDGVFTRQ 365
Score = 40.3 bits (90), Expect = 0.21
Identities = 17/66 (25%), Positives = 39/66 (59%)
Query: 168 GIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFIL 227
G + E+ + K + LL +ARSIF + +++ ++ K+M A+ L+ +R ++F++
Sbjct: 201 GSDGQDIHENIAKQRKLSNFLLDVARSIFHDIVSMDAVIIKVMNFAQKLVDADRASLFLV 260
Query: 228 DTDHCE 233
D+ + +
Sbjct: 261 DSKNAQ 266
>UniRef50_O00408 Cluster: cGMP-dependent 3',5'-cyclic
phosphodiesterase; n=47; Eumetazoa|Rep: cGMP-dependent
3',5'-cyclic phosphodiesterase - Homo sapiens (Human)
Length = 941
Score = 305 bits (748), Expect = 4e-81
Identities = 164/442 (37%), Positives = 253/442 (57%), Gaps = 16/442 (3%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLIN 344
IA VA + + LNI D + ++S G RT +LC PI N N++VIGVA+L+N
Sbjct: 465 IAGHVATTGQILNIPDA--YAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVN 522
Query: 345 K-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDT 399
K F++ D + AF+I+CG+ I ++ +Y+ + + +A E + YH S ++
Sbjct: 523 KINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEY 582
Query: 400 SKLCQDEIP--SAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRW 457
+KL D I +A N SF + L ++DT A L M + + I L R+
Sbjct: 583 TKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARF 642
Query: 458 ILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRG 517
L VKK YR YHNW HA +V+ + + K ++ ++ D+EI L ++C+CHDLDHRG
Sbjct: 643 CLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRG 702
Query: 518 TNNAFQTKTESPLAILYST--STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVE 575
TNN+FQ ++S LA LYS+ S ME HHF Q + ILN+ NIF S +DY+ ++ ++
Sbjct: 703 TNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMR 762
Query: 576 TAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHR 635
IL+TDLA + + ++ + G +D ++ LL ++MT+CD+S K W+ +
Sbjct: 763 DIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRK 821
Query: 636 IAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
IA+L+ EFF QGDLEK + +P+ MMDREK +P++Q+ F++ I +P+YK+L D FP
Sbjct: 822 IAELIYKEFFSQGDLEK-AMGNRPMEMMDREKA-YIPELQISFMEHIAMPIYKLLQDLFP 879
Query: 696 WMTPLRTGTADNRRRWQDLAEK 717
L A NR W ++ K
Sbjct: 880 KAAELYERVASNREHWTKVSHK 901
Score = 44.4 bits (100), Expect = 0.013
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 9/67 (13%)
Query: 29 ISTSGMHTPIPGKIPHKLTAIKYITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQ 88
++T+G IP H L F +D TG++T ILC PI N +V+GVA+
Sbjct: 469 VATTGQILNIPDAYAHPL---------FYRGVDDSTGFRTRNILCFPIKNENQEVIGVAE 519
Query: 89 IINKTDG 95
++NK +G
Sbjct: 520 LVNKING 526
Score = 41.5 bits (93), Expect = 0.093
Identities = 22/79 (27%), Positives = 40/79 (50%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F+ D V + + + + F+ Q LL +A+++F ++ L+ +I
Sbjct: 358 FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEI 417
Query: 210 MTEARDLLKCERCAVFILD 228
+TEAR+L E C+VF+LD
Sbjct: 418 ITEARNLSNAEICSVFLLD 436
>UniRef50_Q4RG61 Cluster: Chromosome 2 SCAF15106, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 2
SCAF15106, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 899
Score = 298 bits (732), Expect = 3e-79
Identities = 164/427 (38%), Positives = 243/427 (56%), Gaps = 56/427 (13%)
Query: 321 VRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENAC 375
++ +L +PIVN ++++G+A N+ F E D I EA F G + N Y+
Sbjct: 412 IKNVLSLPIVNKKEEIVGIATFFNRKDGKPFDEHDEQITEALTQFLGWSVLNCDTYDKLN 471
Query: 376 KLMAKQKVALECLSYHAT-----------------ASAEDTS-----KLCQDEIPSAETY 413
++ ++ +A E L Y A ED KL + P A+
Sbjct: 472 RMEYRKDIAQEMLMYQTRCTKDEMQTILNTKDKFDAEPEDCDQKEMYKLLKSTCPPADNI 531
Query: 414 N---LYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYD---------------VLC 455
N LYSF F DF +++ D +A +RMF + +VEKF +P + L
Sbjct: 532 NGENLYSFAFSDFPVSEFDLIKAGIRMFFELGVVEKFKVPAEDHKRAFSPFLGSLLQTLT 591
Query: 456 RWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDH 515
RW+ +V+K YR + YHNWRH NV TMF +L+TG++ ++ SDL+ ++ A CHD+DH
Sbjct: 592 RWMYTVRKGYRAITYHNWRHGFNVGHTMFCLLQTGRLRKYYSDLDAFAMVAAAFCHDIDH 651
Query: 516 RGTNNAFQTKTES-PLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVV 574
RGTNN +QTK + PLA L+ TS ME HH + ++ E+ NIF L R ++ V H+
Sbjct: 652 RGTNNLYQTKRSAHPLAKLHGTSIMERHHLEYSKTLMAEETLNIFCNLQKRQFEHVQHLF 711
Query: 575 ETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQE----------KKELLCGMMMTACDVS 624
+ I++TDLA+YFKK++ F +V+ E +E +KE++ MMMT CD+S
Sbjct: 712 DVCIIATDLALYFKKRTMFQNIVNATEPMADEKEAIGYVSNNPIRKEIVMAMMMTGCDLS 771
Query: 625 AIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICL 684
AI KPWEVQ ++A +VA EF++QGDLE+ L+QQPI MMDR ++LP+MQ GFID +C
Sbjct: 772 AITKPWEVQSKVALMVAAEFWEQGDLERNVLDQQPIPMMDRNCAEQLPKMQCGFIDFVCS 831
Query: 685 PLYKVLS 691
+YKV++
Sbjct: 832 FVYKVMN 838
Score = 50.8 bits (116), Expect = 2e-04
Identities = 29/88 (32%), Positives = 52/88 (59%), Gaps = 2/88 (2%)
Query: 142 LSHSGSKEFSSRDVEVFRRYLTFCG-IGIQNAQLFESSVLEYKRNQILLALARSIFEEQS 200
L+ G+ F++ D ++F +Y+ F I +Q+ + +V E +R+Q+LL A +FEE +
Sbjct: 222 LNKIGAPAFTAEDEQLFHKYMNFAQVITLQHYTAYMFNV-ESRRSQVLLWSASKVFEELT 280
Query: 201 NLECLVTKIMTEARDLLKCERCAVFILD 228
++E K + R L+CER +V +LD
Sbjct: 281 DIERQFHKALYTVRTYLQCERYSVGLLD 308
>UniRef50_O96076 Cluster: EFPDE2; n=1; Ephydatia fluviatilis|Rep:
EFPDE2 - Ephydatia fluviatilis
Length = 819
Score = 291 bits (714), Expect = 5e-77
Identities = 156/442 (35%), Positives = 246/442 (55%), Gaps = 17/442 (3%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLIN 344
IA VA++ +NI D ++ + + S G T +LC PI++ N V+GVA+L N
Sbjct: 373 IAGYVAKTGTIVNIVDAQK--HPQFFAEVDKSTGFHTKHILCFPIMDNNGVVVGVAELCN 430
Query: 345 K-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDT 399
K FT+ D + F+ +CG+ I+++++YE + +A E + YH ++
Sbjct: 431 KINGKFFTKYDEELARTFSAYCGISIYHSKLYETVMASQGRSSLATELMLYHMKIRPDEL 490
Query: 400 SKLCQDEIPSAETYN--LYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRW 457
+ + +P +++ + F D+ + A + M + +L+ KF + D+L R+
Sbjct: 491 ERATKTPLPPVSSFHEHMCKLTFSPLDIKNSADEIAVMSMMNEMDLINKFQLHPDILARF 550
Query: 458 ILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRG 517
++ VKK YR YHNW HA +VA ++A+ + DLE+L L V+CLCHD+DHRG
Sbjct: 551 VIMVKKGYRDPPYHNWMHAFSVAHFLYALYCCSSKLSCLDDLEVLALFVSCLCHDIDHRG 610
Query: 518 TNNAFQTKTESPLAILYST--STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVE 575
TNNAFQ + S LA LYS+ S ME HH Q + ILNS NIF+ LS DY+ + +++
Sbjct: 611 TNNAFQVCSNSTLACLYSSEGSVMERHHLAQTLCILNSPGCNIFENLSDSDYRTTIQLIQ 670
Query: 576 TAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHR 635
IL TD+A + KK ++ ++G ++ E L+C ++MT+CD++A K WE
Sbjct: 671 DNILDTDIASHLKKLKHIKQMANDG-YERSNPEHHRLMCSLIMTSCDLTASCKTWESNKA 729
Query: 636 IAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
I+ L+ EFF QGDLEK L P MMDR++ +P+ Q+ F+D I P+Y++LS P
Sbjct: 730 ISDLIYQEFFSQGDLEK-ALGVTPSEMMDRDRA-FIPEQQLQFLDNIAGPVYQLLSRLLP 787
Query: 696 WMTPLRTGTADNRRRWQDLAEK 717
DNR +W D+ +K
Sbjct: 788 ESAAAYHTLLDNREQW-DILKK 808
Score = 54.8 bits (126), Expect = 9e-06
Identities = 26/84 (30%), Positives = 45/84 (53%)
Query: 145 SGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLEC 204
+ + F+ D E L FC + N +++ + K+N++LL +A+++F NL
Sbjct: 261 NNDRPFTKHDEEGLLYSLHFCSSMLNNTLVYQRELALKKQNEVLLQVAKNLFTSLDNLVS 320
Query: 205 LVTKIMTEARDLLKCERCAVFILD 228
L+ IM A L ERC++F+LD
Sbjct: 321 LLRGIMNAASSLTNAERCSLFLLD 344
Score = 49.2 bits (112), Expect = 5e-04
Identities = 22/46 (47%), Positives = 32/46 (69%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
QF +E+D TG+ T+ ILC PI + G VVGVA++ NK +G+ T+
Sbjct: 394 QFFAEVDKSTGFHTKHILCFPIMDNNGVVVGVAELCNKINGKFFTK 439
>UniRef50_A7SW30 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 600
Score = 281 bits (688), Expect = 7e-74
Identities = 159/423 (37%), Positives = 242/423 (57%), Gaps = 32/423 (7%)
Query: 287 IALAVARSNKSLNISDV---EQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLI 343
IA VA + LNI D E++ R+ +M G + T+LC+P V +IGV Q++
Sbjct: 200 IAGYVACTGSILNIRDAYRDERFNREVDMKTGYTT---HTILCVP-VRCKGSIIGVCQMV 255
Query: 344 NK----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDT 399
N F+ D+ FE FA +CGL +H ++MY + K +VALE +SYH AS ++T
Sbjct: 256 NSHNGFFSPNDMQSFEMFAGYCGLALHYSKMYNSLFCAQQKHQVALEVISYHCCASEKET 315
Query: 400 SKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWIL 459
+ + SA+ L ++ F A + + + F + + + R+ L
Sbjct: 316 EEF----LNSADLVMLPP-AYYPFSYLS-----ALIFVLI-------FRVDLETIARFSL 358
Query: 460 SVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTN 519
SV+K YR + YHNW HA +VA +++ +++ K ++D E L L +A +CHD+DHRG N
Sbjct: 359 SVRKCYRDIPYHNWCHAFSVAHSLWIVIRDNKS---LTDYEKLSLFIAGICHDVDHRGKN 415
Query: 520 NAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAIL 579
NAF ++PLA LY+TSTME HHF Q V IL SE N+F L Y+ V+ +++ AI+
Sbjct: 416 NAFMLHCKTPLANLYTTSTMEWHHFKQGVFILESEGQNVFGQLDAESYRRVLELIQEAII 475
Query: 580 STDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKL 639
+TDL ++F K + L +N F W+ ++ + L+ ++MTACD+ AKPW++Q
Sbjct: 476 ATDLMLFFGNKKELETLQENKAFRWEEEKHRSLIRCLLMTACDLCTSAKPWDIQVVAVNK 535
Query: 640 VADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTP 699
V +EF+ QGD E+ ++ P+ MMDR K D+LP+ QVGF+ I P Y +L D P M P
Sbjct: 536 VFEEFYIQGD-EERKMGLDPLPMMDRSKHDDLPENQVGFLKGIVRPCYSLLMDFVPEMAP 594
Query: 700 LRT 702
L T
Sbjct: 595 LIT 597
Score = 60.9 bits (141), Expect = 1e-07
Identities = 28/83 (33%), Positives = 47/83 (56%)
Query: 146 GSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECL 205
GS F D E+ YL + I I +A++ + + N LL + RSIF+E ++ +
Sbjct: 84 GSMPFEKEDEEILNSYLVWGSIAIHHAEISKQITKQKDLNTFLLNVVRSIFDEVCTMDTV 143
Query: 206 VTKIMTEARDLLKCERCAVFILD 228
+ KIM A+ L+ +RC++F+LD
Sbjct: 144 IEKIMAFAKKLVNADRCSLFLLD 166
Score = 46.8 bits (106), Expect = 0.002
Identities = 18/41 (43%), Positives = 29/41 (70%), Gaps = 1/41 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDG 95
+FN E+D +TGY T ILC+P+ +G ++GV Q++N +G
Sbjct: 221 RFNREVDMKTGYTTHTILCVPV-RCKGSIIGVCQMVNSHNG 260
Score = 37.1 bits (82), Expect = 2.0
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 11/107 (10%)
Query: 278 RRPHDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRT---LLCMPIVNANK 334
R+P +A VA + + L I D+ L D G G+ T +LC PI+ ++
Sbjct: 15 RQPIGKGGTVAAHVAETGERLFIKDI---LGDERFPKGIGVEGMTTAMSVLCQPIIQSDG 71
Query: 335 DVIGVAQLIN-----KFTEGDVSIFEAFAIFCGLGIHNTQMYENACK 376
++GV +L+ F + D I ++ ++ + IH+ ++ + K
Sbjct: 72 TLVGVVELVKALGSMPFEKEDEEILNSYLVWGSIAIHHAEISKQITK 118
>UniRef50_UPI0000E48F4D Cluster: PREDICTED: similar to camp and
camp-inhibited cgmp 3,5-cyclic phosphodiesterase; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
camp and camp-inhibited cgmp 3,5-cyclic
phosphodiesterase - Strongylocentrotus purpuratus
Length = 1197
Score = 280 bits (686), Expect = 1e-73
Identities = 130/270 (48%), Positives = 178/270 (65%), Gaps = 2/270 (0%)
Query: 451 YDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLC 510
YD LCR+IL+V+KNYR V YHNW HA +VA +++ M+ TG+ + F + LE L L VACLC
Sbjct: 14 YDELCRFILTVRKNYRRVPYHNWTHAFSVAHSVYTMIMTGQGQVF-NPLEALALFVACLC 72
Query: 511 HDLDHRGTNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDV 570
HDLDHRG NNAF T SPLA +YSTSTMEHHHF+ + IL ++ +NIF+ LS +YK V
Sbjct: 73 HDLDHRGKNNAFMVNTASPLASVYSTSTMEHHHFNMTITILQNDGHNIFKHLSSEEYKQV 132
Query: 571 MHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPW 630
+ + AIL+TDLA++F K+K ++V+ F W QE ++ + + MTACD++A KPW
Sbjct: 133 LGDIRHAILATDLALFFPNKAKLKKIVEEKNFSWDNQEHRQCVKALSMTACDLAANTKPW 192
Query: 631 EVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVL 690
+Q + K++ DEF+ QGD EK + PI MMDR++ ELP QV FI ICLP Y +L
Sbjct: 193 HIQQQTVKVIFDEFYQQGDEEK-AAGRNPIPMMDRDRAHELPANQVSFIVGICLPCYDLL 251
Query: 691 SDTFPWMTPLRTGTADNRRRWQDLAEKVDM 720
+ P P+ G A + +L V +
Sbjct: 252 AQLVPSAKPMYEGAASMNNKLDELYATVQV 281
>UniRef50_UPI00015B4531 Cluster: PREDICTED: similar to cyclic GMP
stimulated phosphodiesterase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cyclic GMP
stimulated phosphodiesterase - Nasonia vitripennis
Length = 1684
Score = 266 bits (651), Expect = 2e-69
Identities = 155/404 (38%), Positives = 225/404 (55%), Gaps = 22/404 (5%)
Query: 322 RTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACK 376
R +LC PI + N +IGVAQL NK F D + AF+I+CG+ I ++ +Y+
Sbjct: 282 RNILCFPIRDEN-GIIGVAQLCNKINGLYFDVFDEEVAMAFSIYCGISIMHSIVYKKIQD 340
Query: 377 LMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQ-FHDFDLT---DEDTCR 432
A+ K++ E + YH ED L + + +N+ F FH T C
Sbjct: 341 AQARSKLSNELMMYHMQVEEEDVQAL----LNCGDDHNIKDFDTFHFCPRTVPYRHMPCY 396
Query: 433 ATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKM 492
L+MF + ++ I VL R+IL VKK YR YHNW HA +VA + ++K +
Sbjct: 397 V-LKMFADLNFIRRWKIRKTVLARFILYVKKGYRDAPYHNWMHAFSVAHFAYLLMKNLNL 455
Query: 493 ER--FMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST--STMEHHHFDQCV 548
R +M+ L+ L LV+CLCHD+DHRGTNN+FQTK + LA LYS+ S ME HH Q +
Sbjct: 456 VRDGYMTSLQALVFLVSCLCHDIDHRGTNNSFQTKCGTILASLYSSEGSVMERHHLAQSM 515
Query: 549 MILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQE 608
ILN+E NIF+ LS +Y + + ++ IL+TDLA +F+ + ++ G +D +
Sbjct: 516 CILNTEGCNIFENLSSEEYSEALDLLRNNILATDLASHFRSVEEQRDVTKQG-YDKNNPK 574
Query: 609 KKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKK 668
+++L M MT CD++ K W V + A+ + DEFF QGDLEK + PI MMDRE+
Sbjct: 575 HQKILHAMFMTCCDLNDQTKNWRVSKQTAEQIYDEFFSQGDLEK-SMGTAPIEMMDRERA 633
Query: 669 DELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
+P +QV FI + LPL+ L+ FP M P+ NR W+
Sbjct: 634 -SIPDLQVQFITNLVLPLFTNLATLFPSMQPIVHIIERNREIWR 676
Score = 44.4 bits (100), Expect = 0.013
Identities = 20/48 (41%), Positives = 33/48 (68%)
Query: 186 QILLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILDTDHCE 233
Q LL +++ +F +L L+ +IMTEAR L K ERC++F+L+++ E
Sbjct: 174 QDLLVVSKKLFTRLGDLTDLLREIMTEARKLTKAERCSLFLLESEQQE 221
Score = 40.3 bits (90), Expect = 0.21
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDG 95
F ID TG+KT ILC PI + E ++GVAQ+ NK +G
Sbjct: 269 FYRGIDEVTGFKTRNILCFPIRD-ENGIIGVAQLCNKING 307
>UniRef50_UPI0000588CD9 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 701
Score = 254 bits (621), Expect = 1e-65
Identities = 146/439 (33%), Positives = 231/439 (52%), Gaps = 14/439 (3%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA++ +NI D Q R N + R++LCMPI + +IGV Q+INK
Sbjct: 251 IAGHVAKTGDIVNIPDAYQDRRFNREVDVKTGYSTRSILCMPITSHGL-IIGVVQMINKM 309
Query: 346 --------FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAE 397
F + D S F+ FA++C L +H +++Y ++ + V E L Y+ T S +
Sbjct: 310 GQDGQTTAFDQTDESNFKIFAMYCALALHFSRIYRDSQQSERNLAVVQEQLIYYTTCSEQ 369
Query: 398 DTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRW 457
+L + T QF DF + + +++ +L L R+
Sbjct: 370 QVDRLLNSWNKQSFTVPTEIEQF-DFHSRPYVSSLNEIFIYMVQKLFGPSSFDLTTLARF 428
Query: 458 ILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRG 517
IL+V+K+YR V +HN+ HA +V MF +L + RF +D E+ + +CHD+DHRG
Sbjct: 429 ILTVRKHYRLVPFHNFCHAFDVCHCMFMILLHSE-GRF-TDEEMYAMFFGSICHDMDHRG 486
Query: 518 TNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETA 577
N+F K +PL LYS+S ME HHF V IL+ E N+F L P +K ++ +++
Sbjct: 487 LTNSFHAKFGTPLGKLYSSSIMESHHFAMIVSILHREGFNVFSHLPPDTFKKIVDLIQDI 546
Query: 578 ILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIA 637
I+STDL +F + +L+ FDW + + M MTACD+ A K W +Q +I
Sbjct: 547 IMSTDLTNFFPNHKELSKLLVAQTFDWTIDHHRWSIRNMCMTACDLCASTKMWPIQQQIV 606
Query: 638 KLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWM 697
+ + +EF+ QGD+EK + + PI M+DR+ + Q Q+ F+ +CLP + ++D P
Sbjct: 607 ECLYEEFYSQGDIEK-ERGETPIQMLDRDNQPNRAQEQIEFLTNVCLPCFSDIADLLPES 665
Query: 698 TPLRTGTADNRRRWQDLAE 716
PL +G DN ++WQ + E
Sbjct: 666 QPLLSGCKDNLQQWQLVKE 684
Score = 51.6 bits (118), Expect = 9e-05
Identities = 26/57 (45%), Positives = 39/57 (68%), Gaps = 4/57 (7%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK--TDGEHTT-ESTLDHNYE 108
+FN E+D +TGY T ILCMPI ++ G ++GV Q+INK DG+ T + T + N++
Sbjct: 272 RFNREVDVKTGYSTRSILCMPITSH-GLIIGVVQMINKMGQDGQTTAFDQTDESNFK 327
>UniRef50_Q4RNP2 Cluster: Chromosome 2 SCAF15010, whole genome
shotgun sequence; n=58; Fungi/Metazoa group|Rep:
Chromosome 2 SCAF15010, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1093
Score = 252 bits (617), Expect = 3e-65
Identities = 182/555 (32%), Positives = 266/555 (47%), Gaps = 74/555 (13%)
Query: 157 VFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSN--LECLVTKIMTEAR 214
V + YL FCGI I NAQLF +S EY R+++ L + S L ++ + R
Sbjct: 405 VLQMYLPFCGIAISNAQLFAASRKEYDRSRVRLVQPHPFMVQVSEELLGDTCQTLIADGR 464
Query: 215 DLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXX----XXXXXXXXXXXXTRFHT 270
+ L+ + D E + LE+IV+ +F
Sbjct: 465 EQLEPTALLEVVNDLFE-EQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTK 523
Query: 271 VFELGAPRRPHDALPA------------------IALAVARSNKSLNISDVEQWLRDNNM 312
FEL +P+ DA + IA VA + +NISD Q R +
Sbjct: 524 SFELLSPKCSADADSSFKDSMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAE 583
Query: 313 SAGENSAGVRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFE------------ 355
+ + +R++LC+PI N+N +IGVAQ++N+ F + D +FE
Sbjct: 584 ADQFSDFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEVFLFDSAWAPRL 643
Query: 356 --------------AFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSK 401
AF IFCGLGI+NT MY+ K AKQ VAL+ LSYHAT S + K
Sbjct: 644 RRRLANGCLLVSSQAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDK 703
Query: 402 LCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSV 461
IP + F DF L + A LRMF++ +V+KF I Y+ LCRW+L+
Sbjct: 704 FKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFIELGMVQKFKIDYETLCRWLLTC 763
Query: 462 KKNYRP-VKYHNWRHALNVAQTMFAMLKTGKMERFMSDL----EILGLLVACL------- 509
+K R V YHNWRH+L G++ G+ V L
Sbjct: 764 QKKLRDMVLYHNWRHSLQRLPVHVCDAHDGRLPGDPDGCGDPGAHRGMCVPRLGPQGHQQ 823
Query: 510 CHDLDHRGTNNAFQTK-----TESPLAILYSTS-TMEHHHFDQCVMILNSESNNIFQALS 563
C H + A Q + T S L++LY TS T+EHHHF+ VMIL SE +NIF LS
Sbjct: 824 CFPGQHLQQSAALQRESNGKWTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFCNLS 883
Query: 564 PRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDV 623
+Y D+M +++ +IL+TDL +YF+ ++ F ELV NGE++W + +++ MMMTACD+
Sbjct: 884 STEYSDLMQLLKQSILATDLTLYFENRNNFFELVSNGEYNWNVKTHRDMCRSMMMTACDL 943
Query: 624 SAIAKPWEVQHRIAK 638
A+ KPW++ ++ +
Sbjct: 944 GAVTKPWDISRKVRR 958
Score = 58.8 bits (136), Expect = 6e-07
Identities = 26/59 (44%), Positives = 38/59 (64%)
Query: 659 PIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
P A+ DR +KDELP +Q+G+ID IC PLY+ L P + P+ NR +W++L +K
Sbjct: 1023 PQAIFDRNRKDELPGLQLGWIDGICTPLYETLVKLNPKLQPMVDMIKANRAKWEELDKK 1081
Score = 58.0 bits (134), Expect = 1e-06
Identities = 29/63 (46%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD-GEHTTESTLDHNYEPRPGQ 113
+F+ EID TGYKT+ +LCMPI N +G+++GVAQ INK+ G+ TE + E P
Sbjct: 265 RFSDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSSAGQLFTEDDEKFSGELAPFS 324
Query: 114 ITR 116
+ R
Sbjct: 325 LRR 327
Score = 43.2 bits (97), Expect = 0.030
Identities = 23/61 (37%), Positives = 36/61 (59%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINKFTEGD 350
VA +++NI D Q R ++ ++LLCMPI N++ ++IGVAQ INK + G
Sbjct: 248 VAEHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSSAGQ 307
Query: 351 V 351
+
Sbjct: 308 L 308
Score = 41.1 bits (92), Expect = 0.12
Identities = 15/42 (35%), Positives = 28/42 (66%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
+F++E D + + +LC+PI N ++GVAQ++N+ DG+
Sbjct: 579 RFDAEADQFSDFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGK 620
>UniRef50_Q17L35 Cluster: Cgmp-dependent 3,5-cyclic
phosphodiesterase; n=2; Culicidae|Rep: Cgmp-dependent
3,5-cyclic phosphodiesterase - Aedes aegypti
(Yellowfever mosquito)
Length = 502
Score = 239 bits (584), Expect = 3e-61
Identities = 152/447 (34%), Positives = 233/447 (52%), Gaps = 27/447 (6%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLIN 344
IA VA++ LNI + Q + S G +T +LC PI + + VIGVAQL N
Sbjct: 47 IAGYVAQTGNLLNIRNAYQ--HPLFYKGVDESTGFKTRNILCFPICD-EQGVIGVAQLCN 103
Query: 345 K-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDT 399
K F + D + AF+++CG+ I + +++ K A+ K++ E L YH DT
Sbjct: 104 KLNGFHFDKCDEEVATAFSVYCGISIMHALVHKQVQKAEARYKLSQELLLYHM--KVPDT 161
Query: 400 SKLCQDEIPSAETYNLYSFQFHDFDLTDED------TCRATLRMFLQCELVEKFHIPYDV 453
E +A + ++ FD + + + +++MF V F IP D
Sbjct: 162 EIQHVLEAVNAHEADQFAMDLPRFDFCPREVKNYALSVQLSIKMFYDLNFVTTFQIPEDK 221
Query: 454 LCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKM--ERFMSDLEILGLLVACLCH 511
L R+IL V+K YR YHNW HA +VA ++++ K+ ++ ++ L+A CH
Sbjct: 222 LARFILLVQKGYRDTPYHNWWHAFSVAHFAYSLMVNLKLIENGVITKMQGFSFLIAAFCH 281
Query: 512 DLDHRGTNNAFQTKTESPLAILYST--STMEHHHFDQCVMILNSESNNIFQALSPRDYKD 569
DLDHRGT+N +QT++ SPLA LYS+ S E HH Q + ILN S+ I +LS ++K+
Sbjct: 282 DLDHRGTSNTYQTQSSSPLARLYSSEGSVNERHHLSQAICILNDSSSKILDSLSTEEFKE 341
Query: 570 VMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKP 629
+ + IL+TDLA +F+ L + Q LL +M+T CD+S K
Sbjct: 342 CIDFLRDLILATDLANHFRIMPHLKRLRPENLGEGSNQ---RLLLSLMITCCDLSDQVKS 398
Query: 630 WEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKV 689
W+ +A LV EFF +GDLEK Q+ +P AMMDR KK +P +Q+ F+ + P +++
Sbjct: 399 WKTVQHVAHLVYAEFFAEGDLEK-QMGLRPNAMMDR-KKACIPVLQIEFLTMVVRPTFEI 456
Query: 690 LSDTFPWMTPLRTGTADNRRRWQDLAE 716
L+ FP NR++W D+ E
Sbjct: 457 LAQIFPETQHFLETIDCNRQQWVDIKE 483
Score = 49.2 bits (112), Expect = 5e-04
Identities = 22/42 (52%), Positives = 29/42 (69%), Gaps = 1/42 (2%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEH 97
F +D TG+KT ILC PIC+ +G V+GVAQ+ NK +G H
Sbjct: 69 FYKGVDESTGFKTRNILCFPICDEQG-VIGVAQLCNKLNGFH 109
>UniRef50_A2F408 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1086
Score = 223 bits (544), Expect = 2e-56
Identities = 145/573 (25%), Positives = 276/573 (48%), Gaps = 20/573 (3%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSN-LECLVTK 208
F D+ + + FCGI + NA+L+E+S+ ++ + + ++ S+ QSN L +T
Sbjct: 498 FDEEDIRLLIGFNVFCGISLDNAKLYEASLNLARQVRSFVDISTSL--NQSNALRNTLTD 555
Query: 209 IMTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXXXTRF 268
I+T A + ++ +D + + I++ +
Sbjct: 556 ILTNAMAAINGTGATLYRVDKE-------KAIIELVHVGGPAKYGELFAKEVADLGQPKI 608
Query: 269 HTVFELGAPRRPHDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMP 328
+T ++ + + A+ + + + + + +R ++ G +SA + C+P
Sbjct: 609 YTADQIAEKLQSLNLQNAVEEMLGNTEAAAKLENQASRVR-RSVLFGSDSAICEQICCLP 667
Query: 329 IVNANKDVIGVAQL--INKFTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
++N+ +VIGV L I + D+S+ + FAIF + + +++ + A KL + + E
Sbjct: 668 LINSEGEVIGVMLLMSIQRMMNEDMSLLDCFAIFAAVSLERSELKDIA-KLGS---IEFE 723
Query: 387 CLSYHATASAEDTSKL-CQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVE 445
+ A E T+++ + ++P E+ L+ F + +F + + E
Sbjct: 724 LKEWVADNERELTNQIPVKLQLPIEESSKLWIVSFDAPKWAGIGFFKEVFAIFARFKFQE 783
Query: 446 KFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLL 505
+ I + L R++ ++ Y V YHNWRHA +V Q + + E+ +S++E+ L+
Sbjct: 784 NYGISNEKLFRFLCELRDTYNKVPYHNWRHACDVTQFVTYEIILSGAEKILSNMELFALI 843
Query: 506 VACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSP 564
VA LCHD +H G N F K E+PL IL+ + S ME HH + + I++ E N+F L
Sbjct: 844 VAALCHDANHDGFTNVFNEKAETPLGILFKNQSVMETHHCEVAIGIISKEETNLFAKLKS 903
Query: 565 RDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVS 624
+D+K + + IL+TD++ +F +F L D G++D + + + +++ D+S
Sbjct: 904 QDFKFMWTTIIELILATDMSKHFTLLKEFKALNDEGKWDKTQPDIRLRMMKLLLKTADIS 963
Query: 625 AIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICL 684
+++P+E+ R ++ +EFF QGDLE Q + DRE D+ P+ Q+GF +CL
Sbjct: 964 NVSRPFELADRWCDVLCEEFFRQGDLEMASGMQYTSDLNDREHLDK-PKSQIGFYTFVCL 1022
Query: 685 PLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
PLY+ + FP + N W+ EK
Sbjct: 1023 PLYQATAQAFPPLEVNVQQVQSNLAVWKAAFEK 1055
Score = 52.4 bits (120), Expect = 5e-05
Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA A + +++NI D + + + +++L PI N ++IGV ++INK
Sbjct: 434 IAGKTATTGETINIQDAYNDVNFDRSIDAKTGYRTKSILATPIYNNRGEIIGVTEMINKC 493
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKL 377
F E D+ + F +FCG+ + N ++YE + L
Sbjct: 494 NDGIFDEEDIRLLIGFNVFCGISLDNAKLYEASLNL 529
Score = 50.4 bits (115), Expect = 2e-04
Identities = 22/46 (47%), Positives = 32/46 (69%), Gaps = 1/46 (2%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK-TDG 95
Y + F+ IDA+TGY+T+ IL PI N G+++GV ++INK DG
Sbjct: 451 YNDVNFDRSIDAKTGYRTKSILATPIYNNRGEIIGVTEMINKCNDG 496
>UniRef50_A2FKH2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1086
Score = 221 bits (541), Expect = 5e-56
Identities = 154/584 (26%), Positives = 285/584 (48%), Gaps = 29/584 (4%)
Query: 129 FGNQRLYTYLRRKLSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQIL 188
+ N+ T + ++ + F+ DV + + FCG + NA+L+++S+ K+ + L
Sbjct: 466 YNNRGEITGVTEMINKLDGEGFTEDDVRMMHPFNVFCGTSLDNAKLYKASIDLTKQLRTL 525
Query: 189 LALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILDTDHCESSHLERI---VQXXX 245
++ ++ + + L +V +I+ AR ++ R +FI D++ + I ++
Sbjct: 526 TKMS-AVLGQGTQLTGVVEEILENARSIVSASRATLFIYDSNERITKQFANIGNEIKYGT 584
Query: 246 XXXXXXXXXXXXXXXXXXXXTRFHT--VFELGAPRRPHDALPAIALAVA----RSNKSLN 299
R + V E + + PA + + RS+KS N
Sbjct: 585 MFADIVVNERETKIFSSMDIARLTSKNVLESAIEKLMSEPPPAEIFSSSNLSTRSSKS-N 643
Query: 300 ISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQL-IN-KFTEGDVSIFEAF 357
+S + DNN S + ++ +P+++++ ++GV +L N K D+ I + F
Sbjct: 644 LSFLSS-SSDNNNSVAQQQNVNESICSIPLMDSSGIILGVMELECNWKIINEDMDILDCF 702
Query: 358 AIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQD-EIPSAETYNLY 416
A+F + I + + A +V ++ L + T S D + Q ++P +
Sbjct: 703 AVFASVAIERANLKDIA----EHGQVEID-LKHWLTESERDGYSVPQSFQLPQEVIDGFF 757
Query: 417 SFQFHDFDLTDE-DTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRH 475
+ F D + D + +F +++ F + + R++ +++ Y+ V YHNWRH
Sbjct: 758 TVNF-DAPMWDGIGHFKVIFNIFHHFGVLQIFKVTNEKFFRFLTALRDKYKKVPYHNWRH 816
Query: 476 ALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY- 534
A++V Q + L T ++ +S E+ GLLVACLCHD +H G N + K E+PL IL+
Sbjct: 817 AVDVTQFVTYELITSGYDKILSSFELYGLLVACLCHDANHDGFTNVYNVKAETPLGILFK 876
Query: 535 STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFL 594
+ S ME HH + I++ E NIF +L+P +YK + ++ IL TD+A +F +F
Sbjct: 877 NQSVMETHHCAIAIDIISKEETNIFASLNPAEYKKMWSLIINLILITDMAKHFTFLKEFN 936
Query: 595 ELVDNGEFDWQAQEKKE---LLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE 651
L D GE W+ +E + +L M++ D+S +++P+E+ + ++ +EFF QGDLE
Sbjct: 937 GLFDAGE--WKPKENPQHFLMLMQMLLKCGDISNVSRPFELADKWCDVLCEEFFRQGDLE 994
Query: 652 KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
+ Q + DR D+ P+ Q+GF +CLPLY+ + P
Sbjct: 995 QAQGMNYTSDLNDRAHLDK-PKSQIGFYTFVCLPLYQATAKAIP 1037
Score = 53.2 bits (122), Expect = 3e-05
Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 2/66 (3%)
Query: 35 HTPIPGKIPHKLTAIKYITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
HT I G + + A Y +F+ ID TG++T +L +PI N G++ GV ++INK D
Sbjct: 426 HTAITGNVVNIKDA--YSDTRFDRTIDQTTGFRTVSLLTVPIYNNRGEITGVTEMINKLD 483
Query: 95 GEHTTE 100
GE TE
Sbjct: 484 GEGFTE 489
Score = 48.0 bits (109), Expect = 0.001
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 7/69 (10%)
Query: 316 ENSAGVRT--LLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNT 368
+ + G RT LL +PI N ++ GV ++INK FTE DV + F +FCG + N
Sbjct: 450 DQTTGFRTVSLLTVPIYNNRGEITGVTEMINKLDGEGFTEDDVRMMHPFNVFCGTSLDNA 509
Query: 369 QMYENACKL 377
++Y+ + L
Sbjct: 510 KLYKASIDL 518
>UniRef50_A2DF08 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1040
Score = 220 bits (538), Expect = 1e-55
Identities = 140/576 (24%), Positives = 277/576 (48%), Gaps = 16/576 (2%)
Query: 146 GSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECL 205
GS +F + D+++ + FCGI + NA+L+++S+ K+ + + L+ ++ +
Sbjct: 468 GSDKFDADDIKMLMAFNVFCGISLDNAKLYQASLDLTKQLRTFVDLSAAL-SHADKIRNA 526
Query: 206 VTKIMTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXXX 265
+ I+ A + R ++ +D + + + L
Sbjct: 527 LQSILMSAMKAMDGLRATIYHIDQTNGKLTKLVNAGIEPKYDTIFAQLALQKLAPQIFGA 586
Query: 266 TRFHTVFELGAPRRP-HDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTL 324
+ GA + D ++ A + S + + M +G +A V +
Sbjct: 587 QEIEEIVNSGADNKSVQDDNMSVKSNKANERQRRIASIITRNASIETMKSGGGAAEVN-I 645
Query: 325 LCMPIVNANKDVIGVAQLIN--KFTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQK 382
+C P++ + +GV ++ K ++ + E F++F + I Q+ + KL ++
Sbjct: 646 VCSPMLTSENTPLGVLEIETAVKMMNENLKLLECFSVFAAISIEKFQLID-IVKLGQGER 704
Query: 383 VALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCE 442
+ +S T+K+ E S E +++ F D L + +F + +
Sbjct: 705 ELKQMISDEERTL---TTKI--PEKMSIENDSIWKRHF-DAQLWADQYITVLFNIFYRFD 758
Query: 443 LVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQ-TMFAMLKTGKMERFMSDLEI 501
L ++F+I + L R++ ++ Y+ V YHNWRHA++V Q ++ +L++G ++ ++ E+
Sbjct: 759 LPKEFNITNEKLFRFLTEIRDTYKKVPYHNWRHAVDVTQFVVYELLESG-CDKVLTKFEV 817
Query: 502 LGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNIFQ 560
LLV+ +CHD +H G N + K E+PL IL+ S ME HH + +++ E NIF
Sbjct: 818 FALLVSAVCHDANHDGFTNVYNVKAETPLGILFKNQSVMETHHCQVAIGVISKEECNIFS 877
Query: 561 ALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTA 620
AL+ D + + + + ILSTD+A +F+ F ++D GEF + ++ + LL +++
Sbjct: 878 ALNAGDNRTMWMTIISLILSTDMAKHFEILKNFNAIMDAGEFSMENKDHRILLMQLLLKT 937
Query: 621 CDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFID 680
D+S +++P+++ +R ++ +EFF QGDLE Q + + D+ D+ P+ Q+GF
Sbjct: 938 ADISNVSRPFDIANRWCDILCEEFFRQGDLEMAQGMEYTSDLNDKAHLDK-PKSQIGFYT 996
Query: 681 TICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAE 716
+CLPLY+ L+ FP ++ N W+ E
Sbjct: 997 FVCLPLYQALARAFPQLSVNVKSVQSNLAIWKQTTE 1032
Score = 51.6 bits (118), Expect = 9e-05
Identities = 19/42 (45%), Positives = 31/42 (73%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
Y+ +F+ +D +TGY+T+ ILC+PI N G++ GV ++INK
Sbjct: 425 YLDSRFDKTVDLKTGYRTKSILCLPIYNNRGEIAGVTEMINK 466
Score = 50.4 bits (115), Expect = 2e-04
Identities = 25/91 (27%), Positives = 48/91 (52%), Gaps = 5/91 (5%)
Query: 292 ARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK-----F 346
A + +++NI D R + + +++LC+PI N ++ GV ++INK F
Sbjct: 413 AMTGETVNIEDAYLDSRFDKTVDLKTGYRTKSILCLPIYNNRGEIAGVTEMINKIGSDKF 472
Query: 347 TEGDVSIFEAFAIFCGLGIHNTQMYENACKL 377
D+ + AF +FCG+ + N ++Y+ + L
Sbjct: 473 DADDIKMLMAFNVFCGISLDNAKLYQASLDL 503
>UniRef50_A2DYU6 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1091
Score = 217 bits (530), Expect = 1e-54
Identities = 126/431 (29%), Positives = 215/431 (49%), Gaps = 9/431 (2%)
Query: 292 ARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----FT 347
A+S K + +DV N +LL +P+++ + ++IGV +++NK F
Sbjct: 641 AKSKKGIINNDVYHSPEFNRTVDISTGFKTNSLLAVPVLSGSGELIGVVEMVNKVDNCFN 700
Query: 348 EGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEI 407
D+ I + FA+ + I N ++ A A +++ T + + +KL ++
Sbjct: 701 NKDLEIVQNFAVLSSVAIENDRLKGIATNGSADVEMSKWITEPERTLTDQIPAKL---KL 757
Query: 408 PSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRP 467
+ S F D + R +F + ++ F I ++ R+I ++ Y
Sbjct: 758 TEEQQKVASSLNFFSPDFRGINHIRELFYLFSKFNILRDFKISNELFFRFIYKIRSTYND 817
Query: 468 VKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTE 527
V YHNW HA +V + + LKT + +S LE LL++ +CHD +H G NN F K +
Sbjct: 818 VPYHNWMHACDVTEYVAYELKTSGFDEMLSPLEKFALLLSAVCHDANHEGFNNIFNIKAQ 877
Query: 528 SPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMY 586
+PL +L+ TS ME HH + IL+ +S N+ +LS D K + ++ IL+TD+A +
Sbjct: 878 TPLGLLFKDTSVMETHHLTVSIDILSDDSYNLIYSLSEEDTKKMWQMMIQNILATDMAKH 937
Query: 587 FKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFD 646
F+ LVD GEFD +E + + +++ D+S +++P+E+ ++ EF+
Sbjct: 938 FEMIKTTKALVDAGEFDLNKEEHRRIAMSLLLKVADISNVSRPFELADNWCDILNVEFYR 997
Query: 647 QGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTAD 706
QGDLEK + DRE D+ P+ Q+GF + +CLPLY V++ FP +
Sbjct: 998 QGDLEKATGIGLTSPLNDREHPDK-PKSQIGFYNFVCLPLYNVVATIFPKLQVNADSVKS 1056
Query: 707 NRRRWQDLAEK 717
N W +LAEK
Sbjct: 1057 NLAVWMELAEK 1067
Score = 54.0 bits (124), Expect = 2e-05
Identities = 33/118 (27%), Positives = 64/118 (54%), Gaps = 7/118 (5%)
Query: 298 LNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVS 352
+NI+D + + + E R++L +PI N ++IGV ++INK FT+ D++
Sbjct: 480 MNITDAYENQYFDPTTDKETGYRTRSILSVPIYNNRTEIIGVTEMINKNDNKPFTQWDIN 539
Query: 353 IFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSA 410
+ + F +F G+ + N +Y+ A + +Q +L +S+ T ED +L +D + +A
Sbjct: 540 VIQIFNVFAGISLENVFLYKEA-QEKGEQLRSLLDVSFSIT-KREDVQRLLKDILSNA 595
Score = 45.2 bits (102), Expect = 0.008
Identities = 16/44 (36%), Positives = 30/44 (68%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
Y + +FN +D TG+KT +L +P+ + G+++GV +++NK D
Sbjct: 653 YHSPEFNRTVDISTGFKTNSLLAVPVLSGSGELIGVVEMVNKVD 696
Score = 43.2 bits (97), Expect = 0.030
Identities = 18/45 (40%), Positives = 28/45 (62%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
F+ D TGY+T IL +PI N +++GV ++INK D + T+
Sbjct: 491 FDPTTDKETGYRTRSILSVPIYNNRTEIIGVTEMINKNDNKPFTQ 535
>UniRef50_A2D762 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1081
Score = 212 bits (518), Expect = 3e-53
Identities = 121/434 (27%), Positives = 218/434 (50%), Gaps = 10/434 (2%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
+A A +S + + ++ R N EN+ LL PI++ V+G +++NK
Sbjct: 647 LAAAAIKSREVIVSNNCYDDPRFNRTIDIENNFKTERLLVAPIISQKGVVLGAVEMVNKK 706
Query: 346 ---FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKL 402
F + D + ++FA F + + N Q ++ L + + +S +S++ SKL
Sbjct: 707 NGDFDDDDCKLLKSFAAFAAVSLEN-QRLKSIADLGTSEAELPKYISESEKSSSKTPSKL 765
Query: 403 CQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVK 462
++ + + S F D + +F + L+E+F IP D+ R+I +++
Sbjct: 766 ---QLTDEQKKLVSSLNFFSPDYKGVGHIKILFFIFQKFNLLEEFKIPNDMFFRFIFAIR 822
Query: 463 KNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAF 522
+ Y V YHNW H ++V Q + + T ++++ LE+L + VA +CHD H G NN +
Sbjct: 823 EKYNEVPYHNWMHCVDVCQYLAYEVSTAELDKVYKPLELLAMFVAAVCHDAGHEGLNNIY 882
Query: 523 QTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILST 581
K E+PL IL+ S ME HH + +L E N+F ++ + + + IL+T
Sbjct: 883 NVKAETPLGILFKDQSVMETHHCTVAISLLTKEEYNLFHSVDLEHQRQLWTTIIQLILAT 942
Query: 582 DLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVA 641
D+A +FK E+ D EFD + E + L +++ D+S +++P+++ + ++
Sbjct: 943 DMANHFKLVKDTNEIADKAEFDIEKPEHRLLSMKLLLKVGDISNVSRPFQIADKWCDILC 1002
Query: 642 DEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLR 701
+EFF QGD EK + DR D+ P+ Q+GF + +CLPLY+V++ FP +
Sbjct: 1003 EEFFRQGDNEKSLGIGLTSPLNDRLNNDK-PKSQIGFYNFVCLPLYQVVAKLFPPLEVNH 1061
Query: 702 TGTADNRRRWQDLA 715
+N W++LA
Sbjct: 1062 QSVKNNLEVWKELA 1075
Score = 55.6 bits (128), Expect = 5e-06
Identities = 31/104 (29%), Positives = 63/104 (60%), Gaps = 8/104 (7%)
Query: 313 SAGENSAGVRT--LLCMPIVNANKDVIGVAQLINK----FTEGDVSIFEAFAIFCGLGIH 366
S+ + G RT +L +PI+N +VIGV +++NK FTE D + + F +FCG+ +
Sbjct: 505 SSTDLETGYRTKNILSVPIINNRSEVIGVTEMVNKINGKFTEWDAHMIKIFNVFCGISLE 564
Query: 367 NTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSA 410
N ++Y+++ + M++Q + +S+ + +++E ++ D I +A
Sbjct: 565 NARLYQDSVE-MSQQLHSFFDVSF-SLSNSESIQRILGDIIKNA 606
Score = 48.0 bits (109), Expect = 0.001
Identities = 20/48 (41%), Positives = 31/48 (64%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHT 98
Y F+S D TGY+T+ IL +PI N +V+GV +++NK +G+ T
Sbjct: 498 YADPDFDSSTDLETGYRTKNILSVPIINNRSEVIGVTEMVNKINGKFT 545
Score = 40.3 bits (90), Expect = 0.21
Identities = 16/42 (38%), Positives = 27/42 (64%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
+FN ID +KTE +L PI + +G V+G +++NK +G+
Sbjct: 668 RFNRTIDIENNFKTERLLVAPIISQKGVVLGAVEMVNKKNGD 709
Score = 39.1 bits (87), Expect = 0.49
Identities = 23/90 (25%), Positives = 49/90 (54%), Gaps = 2/90 (2%)
Query: 149 EFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTK 208
+F+ D + + + FCGI ++NA+L++ SV ++ ++ S+ +S ++ ++
Sbjct: 543 KFTEWDAHMIKIFNVFCGISLENARLYQDSVEMSQQLHSFFDVSFSLSNSES-IQRILGD 601
Query: 209 IMTEARDLLKCERCAVFILDTD-HCESSHL 237
I+ AR+ + E ++ ILD +C S L
Sbjct: 602 IIKNARNTIGAECASLLILDEPLNCLQSFL 631
>UniRef50_A2DG30 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1090
Score = 212 bits (517), Expect = 4e-53
Identities = 135/574 (23%), Positives = 276/574 (48%), Gaps = 25/574 (4%)
Query: 147 SKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLV 206
S F+ DV + R + FCGI + N++L+++S K+ + ++ + + + + +
Sbjct: 472 SDAFTEDDVSLLRGFNVFCGIALDNSRLYQASTELTKQVSSFIEVSSGL-TKNTTMRNIC 530
Query: 207 TKIMTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXXXXXXXT 266
I+ A ++ + + +++LD + + ++
Sbjct: 531 ESILQNAINICEAKSGILYLLDGNE----KITPLISLNTNRETDQLIVKRCIENKSTVVM 586
Query: 267 RFHTVFE-LGAPRRPHDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLL 325
F V E LG + P +++ ++R N +++ + +N+ +
Sbjct: 587 TFDEVNEYLGKTKGPPKQDKSLSHQLSRVNAAMSRRILPDMFTENS------------IC 634
Query: 326 CMPIVNANKDVIGVAQL--INKFTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKV 383
+P+ +++ +V+GV ++ +K + E FA+F + + + + A +L + +
Sbjct: 635 LIPLKSSDGNVLGVMEVDTTSKLMTESQKLLECFAVFASVSLERNHLKDIA-QLGSHEAE 693
Query: 384 ALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCEL 443
+ ++ S T+ +P L++ F D TD + +F + L
Sbjct: 694 LKQQMTRDERDST--TNIPVHLHLPQRTVTQLWTINFDSLDWTDIGYFQVVFAIFSRFNL 751
Query: 444 VEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILG 503
+ F++ + L R+++ ++ YRPV YHNW HA++V Q + ++ + +E+
Sbjct: 752 QQTFNVTNEKLYRFLIELRAGYRPVPYHNWAHAVDVLQFTAYQVHISHLDEKIPKVELFA 811
Query: 504 LLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQAL 562
LLVA +CHDL+H G N + K E+PL IL+ + S ME HH + + I++++ N+F AL
Sbjct: 812 LLVAAICHDLNHDGFTNDYNVKAETPLGILFKNQSVMEMHHCEVTIDIMSNDQCNLFSAL 871
Query: 563 SPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACD 622
P+ +K V ++V IL+TD+A +F +F L+D F + + + LL +++ D
Sbjct: 872 PPQQFKQVWNLVINLILATDMAKHFTILQEFNTLIDGKTFSMENENHRHLLLQLIIKVGD 931
Query: 623 VSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTI 682
+S +++P+++ +R ++ +EFF QGDLE + Q A+ DRE ++ + Q+GF ++
Sbjct: 932 LSNVSRPFDLANRWCAVLCEEFFRQGDLEMARGMQYSSALNDREHLNK-EKSQIGFYTSV 990
Query: 683 CLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAE 716
CLPLY+ ++ P + N W+ E
Sbjct: 991 CLPLYQSVAKVLPQLESNVVQVESNLETWKSADE 1024
Score = 52.0 bits (119), Expect = 7e-05
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 5/73 (6%)
Query: 322 RTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACK 376
R ++ +PI N ++ GV +L+NK FTE DVS+ F +FCG+ + N+++Y+ + +
Sbjct: 446 RNIITVPIFNNRGEIAGVTELMNKITSDAFTEDDVSLLRGFNVFCGIALDNSRLYQASTE 505
Query: 377 LMAKQKVALECLS 389
L + +E S
Sbjct: 506 LTKQVSSFIEVSS 518
Score = 46.4 bits (105), Expect = 0.003
Identities = 18/46 (39%), Positives = 31/46 (67%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
+F+S +D +TG+KT I+ +PI N G++ GV +++NK + TE
Sbjct: 432 RFDSSVDKKTGFKTRNIITVPIFNNRGEIAGVTELMNKITSDAFTE 477
>UniRef50_P30645 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-2; n=5; Eumetazoa|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-2 - Caenorhabditis elegans
Length = 859
Score = 209 bits (510), Expect = 3e-52
Identities = 134/439 (30%), Positives = 225/439 (51%), Gaps = 14/439 (3%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK---FT 347
VA + +++NI DV + N + S R L+ P+++++ +IGV L NK F+
Sbjct: 235 VASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENGFS 294
Query: 348 EGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAE--DTSKLCQD 405
D + F+ F I + + + ++ + + E A E D +L D
Sbjct: 295 RHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVND 354
Query: 406 EIPSAETY--NLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKK 463
+ + N F F + + RA++ F + + L +L V
Sbjct: 355 PLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSA 414
Query: 464 NYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQ 523
YRPV YHNW HA V + L+T + R +SD+E L LL+ACLCHD+DHRGT N+FQ
Sbjct: 415 GYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQ 474
Query: 524 TKT--ESPLAILYST--STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAIL 579
++ ++PL++LYST S +E HHF Q + +L E +I + L D++ +++ + IL
Sbjct: 475 MQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVIL 534
Query: 580 STDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKL 639
+TD++ + +K+ + ++ G ++ + + + LL ++MTA D+S AK + RIA+
Sbjct: 535 ATDISAHLRKQERIKTMISEG-YNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAEN 593
Query: 640 VADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTP 699
+ EFF QGDLE LQL +P+ MMDR +P +Q+ F+ I +P++++L+ P
Sbjct: 594 IYLEFFAQGDLE-LQLGVKPLEMMDRTNA-YVPTVQIDFLFKIGVPVFQLLASVVPEGRT 651
Query: 700 LRTGTADNRRRWQDLAEKV 718
N W L E+V
Sbjct: 652 TSEAIDANHLCWVALDEEV 670
>UniRef50_A2E8N2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1103
Score = 208 bits (508), Expect = 5e-52
Identities = 117/403 (29%), Positives = 207/403 (51%), Gaps = 10/403 (2%)
Query: 321 VRTLLCMPIVNANKDVIGVAQLINK---FTEGDVSIFEAFAIFCGLGIHNTQMYENACKL 377
V LL P+++ V+GVA++INK F++ D+++ + F F + + N + + KL
Sbjct: 671 VTNLLVYPVLSNKGKVLGVAEMINKPSGFSKADLNLLQFFTSFTAMALQNQNV---SAKL 727
Query: 378 MAKQKVALECLSYHATASAEDTSKLCQDEI--PSAETYNLYSFQFHDFDLTDEDTCRATL 435
A L +A E+ + + P L + D ++++
Sbjct: 728 AADAGSTLSTEEENALNPEEEKKCEIPERLVLPEQIQQKLTLREVFQPDFSEDERVAELF 787
Query: 436 RMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERF 495
F +L++KF+I +L R+I+++++ Y + YHNW HA++V Q M L+ ++ +
Sbjct: 788 YFFQHFDLMKKFNITAGLLYRFIMTIRETYNVIPYHNWTHAVDVTQFMVYQLEKAELSKV 847
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSE 554
S EIL +LVA +CHD +H G NN + K + PL IL+ S +E +H + I++ E
Sbjct: 848 FSPFEILAILVATICHDANHNGFNNQYNEKAQLPLGILFKDMSVLEVYHCTVAIGIISKE 907
Query: 555 SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLC 614
NIF + D + ++ I +TD+ ++F K EL+D+G+FD + L
Sbjct: 908 KTNIFTGIPEEDIPRIWTIIIHMIKATDMKLHFSIVQKAQELLDSGKFDMNDPACRLLSM 967
Query: 615 GMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQM 674
+++ D+S +++P++ ++ ++ +EFF QGD EK + DRE D+ P+
Sbjct: 968 QLLLKVSDISNVSRPFDFANKWCDILNEEFFRQGDNEKKLGLGLSSPLNDRENADK-PKG 1026
Query: 675 QVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
Q+GF + ICLPLY V+ FP ++ +DN + W L K
Sbjct: 1027 QIGFYNFICLPLYNVVKRIFPALSVNADSVSDNLKVWVQLGSK 1069
Score = 50.8 bits (116), Expect = 2e-04
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 316 ENSAGVRTLLCMPIVNANKDVIGVAQLINKF----TEGDVSIFEAFAIFCGLGIHNTQMY 371
E T+L PI N + IGV Q++NK+ T+ D + E F FCG+ I N +++
Sbjct: 500 ETGYKTETILSAPIKNTAGEPIGVTQMVNKYGGNYTQNDARVIEVFNAFCGISIENAKLF 559
Query: 372 ENACKLMAKQKVALEC 387
+ + + + +EC
Sbjct: 560 KESLDNSKRLRAVVEC 575
Score = 49.6 bits (113), Expect = 3e-04
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
++ D V + FCGI I+NA+LF+ S+ KR + ++ A S+ + L L++ I
Sbjct: 534 YTQNDARVIEVFNAFCGISIENAKLFKESLDNSKRLRAVVECAFSL-SKTDKLTLLISDI 592
Query: 210 MTEARDLLKCERCAVFILD 228
M AR + +R VF+LD
Sbjct: 593 MKLARLSIGADRAGVFVLD 611
Score = 47.2 bits (107), Expect = 0.002
Identities = 21/43 (48%), Positives = 27/43 (62%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHT 98
F+ D TGYKTE IL PI N G+ +GV Q++NK G +T
Sbjct: 493 FDPTTDKETGYKTETILSAPIKNTAGEPIGVTQMVNKYGGNYT 535
>UniRef50_A2FQ29 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1175
Score = 204 bits (498), Expect = 8e-51
Identities = 140/577 (24%), Positives = 282/577 (48%), Gaps = 22/577 (3%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
FS DV++ + + F GI + NAQL+++S+ + + + +++++ + S L+ ++ I
Sbjct: 589 FSEEDVKLIQIFNVFTGISLDNAQLYKASLDLSLQMRTFMDMSQTL-TQTSALKRMLEDI 647
Query: 210 MTEARDLLKCERCAVFILDTDHCESSH--LERIVQXXXXXXXXXXXXXXXXXXXXXXXTR 267
+ R ++ A++I++ + ++ +Q +
Sbjct: 648 LKNTRQVVGAVTGAIYIVEDNGISDKPTVMDEDMQSRMEYFEKLKKEEDGGAEANSLNAK 707
Query: 268 FHTVFELGAPRRPHDALPAIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCM 327
+ L ++P + + R +Q + DN+ E S ++C
Sbjct: 708 RAALMRLIRGKQPGQS-DLTQDDIHRKELVEKSVTEKQSIIDNDSDKAEKSM----MVC- 761
Query: 328 PIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQK 382
PI+++++ V+G + K F D+ + E++++F + + + + + A K A+ +
Sbjct: 762 PIISSDRIVLGAVLMQWKKSNPQFNYDDLRLLESYSVFLSISLERSILKKIAMKGGAEVE 821
Query: 383 VALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCE 442
+ LS KL ++ E +YS F + +F++
Sbjct: 822 LQ-SWLSQSERFQQLIPQKL---KLIEEERKMIYSIDFTPVCFDGYGLFKVVFEVFMEFN 877
Query: 443 LVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEIL 502
L ++FHI + L R++ +V++ Y PV YHN+ HA++V Q +LK K+E +S EIL
Sbjct: 878 LFQEFHINSETLFRFLHAVREGYNPVPYHNFLHAVDVMQFAVYLLKKSKLESEISKFEIL 937
Query: 503 GLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQA 561
GL+++CLCHD++H G +N++ K ++PL ILY + S +E HH C+ I+ E N+ ++
Sbjct: 938 GLIISCLCHDINHDGFSNSYNEKAQTPLGILYKNQSVLETHHCSVCISIMTREDCNLLKS 997
Query: 562 LSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTAC 621
L+ D + + +++ IL TD+A +F+ + L+ + N + DW+ +++ +L M++
Sbjct: 998 LNISDTQKMWNLIINLILITDMAKHFEFLQE-LDKIINEKRDWRQNDRQTIL-QMIIKLS 1055
Query: 622 DVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDT 681
D+S I + +E+ R ++ +EFF QGDLEK + + DRE D+ + Q+GF
Sbjct: 1056 DISTIFRKFELADRWTAVLCEEFFRQGDLEKAAGMEYTSPLNDREHLDK-SKSQIGFYTN 1114
Query: 682 ICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKV 718
+CLP + + +N + W++ E+V
Sbjct: 1115 VCLPFANKAAQILDGLDDALKNVNENLQTWKERVEQV 1151
Score = 51.6 bits (118), Expect = 9e-05
Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Query: 292 ARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----FT 347
A + + LNI D + R N + + T+LC+PI + V GV ++INK F+
Sbjct: 531 ATTGEVLNIKDAYEDPRFNRATDLKTGYRTVTVLCVPIFDNKGIVRGVTEMINKIDGYFS 590
Query: 348 EGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
E DV + + F +F G+ + N Q+Y+ + L + + ++
Sbjct: 591 EEDVKLIQIFNVFTGISLDNAQLYKASLDLSLQMRTFMD 629
Score = 48.4 bits (110), Expect = 8e-04
Identities = 21/46 (45%), Positives = 31/46 (67%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
+FN D +TGY+T +LC+PI + +G V GV ++INK DG + E
Sbjct: 547 RFNRATDLKTGYRTVTVLCVPIFDNKGIVRGVTEMINKIDGYFSEE 592
>UniRef50_A2FBN7 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1090
Score = 204 bits (497), Expect = 1e-50
Identities = 116/436 (26%), Positives = 214/436 (49%), Gaps = 11/436 (2%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA + +++ +DV R N + L+ +P++ D++GV ++ NK
Sbjct: 648 IAAQCVKLRRAIVANDVYHDPRFNRSVDTASGFKTNNLVVVPLLTPGGDILGVVEMCNKK 707
Query: 346 ---FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKL 402
F + D + ++FA F + + ++ +N L + +E L + + E +++
Sbjct: 708 DGDFDDHDAKLVQSFASFVEMTLEKFEL-KNIASL---GETEIEMLKWIGESERESCTEI 763
Query: 403 -CQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSV 461
+ + + NL F D D ++ + F + ++F I +L R+I V
Sbjct: 764 PLRLRLKEEQIQNLRQLNFMALDWEPMDRIKSIIYQFYSFGIPQEFRISNQMLFRFIWEV 823
Query: 462 KKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNA 521
+ Y YHNW HA++V Q + ++ G++E + EI +LVA +CHD H G NN
Sbjct: 824 MRTYHSTPYHNWIHAVDVVQYVSYEMRLGELENIFTKFEIFAMLVAAVCHDAGHSGFNNI 883
Query: 522 FQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILS 580
+ K E+PL IL+ S ME +H + IL + N+F +++ K + ++ IL+
Sbjct: 884 YNVKAETPLGILFKEQSVMETYHCTVAISILTRKECNLFHSITEEAQKQMWTLIIKLILA 943
Query: 581 TDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLV 640
TD+A +FK E +D G F+ E++ + +++ D+S +++P++V + ++
Sbjct: 944 TDMAFHFKMVKAATEFMDAGPFNPNDPEQRLIAFQLVLKTADISNVSRPFKVADKWCDVL 1003
Query: 641 ADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPL 700
+EFF QGD EK Q + DR+ D+ P+ Q+GF + +C+PLY V+S FP
Sbjct: 1004 CEEFFRQGDKEKAQAFGLTSPLNDRDNPDK-PKSQIGFYNFVCIPLYSVISRIFPKFEVN 1062
Query: 701 RTGTADNRRRWQDLAE 716
N W+ L++
Sbjct: 1063 LNSVKSNLEVWKSLSQ 1078
Score = 64.5 bits (150), Expect = 1e-08
Identities = 41/127 (32%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
Query: 286 AIALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK 345
A+ LAV + K +NI+D Q + + E+ TLLC+PI N +VIGV +++NK
Sbjct: 481 AVGLAV-KEQKVVNIADAYQDPNFDRSTDIESGYHTNTLLCVPIFNQKGEVIGVTEMVNK 539
Query: 346 -----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTS 400
F+E D + + F +FCG+ I N ++Y+ + M Q + +S A + +ED
Sbjct: 540 LDGKPFSEWDAKVIQIFNVFCGISIQNAKLYKESVD-METQLQSFFDVSV-AVSKSEDMK 597
Query: 401 KLCQDEI 407
++ Q I
Sbjct: 598 EVLQQII 604
Score = 50.0 bits (114), Expect = 3e-04
Identities = 19/45 (42%), Positives = 31/45 (68%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
F+ D +GY T +LC+PI N +G+V+GV +++NK DG+ +E
Sbjct: 503 FDRSTDIESGYHTNTLLCVPIFNQKGEVIGVTEMVNKLDGKPFSE 547
Score = 49.2 bits (112), Expect = 5e-04
Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 148 KEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVT 207
K FS D +V + + FCGI IQNA+L++ SV + Q ++ ++ + + E L
Sbjct: 543 KPFSEWDAKVIQIFNVFCGISIQNAKLYKESVDMETQLQSFFDVSVAVSKSEDMKEVL-Q 601
Query: 208 KIMTEARDLLKCERCAVFILD 228
+I+ +RD + ER ++F+ D
Sbjct: 602 QIIARSRDAAEAERASIFLFD 622
Score = 42.3 bits (95), Expect = 0.053
Identities = 15/42 (35%), Positives = 28/42 (66%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
+FN +D +G+KT ++ +P+ GD++GV ++ NK DG+
Sbjct: 669 RFNRSVDTASGFKTNNLVVVPLLTPGGDILGVVEMCNKKDGD 710
>UniRef50_UPI0000D555D7 Cluster: PREDICTED: similar to
phosphodiesterase 10A; n=4; Tribolium castaneum|Rep:
PREDICTED: similar to phosphodiesterase 10A - Tribolium
castaneum
Length = 745
Score = 203 bits (495), Expect = 2e-50
Identities = 130/417 (31%), Positives = 214/417 (51%), Gaps = 20/417 (4%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VARS ++N+ D + R N + R++LCMPIV + ++GV Q++NK
Sbjct: 321 IASLVARSGITVNVKDAYKDARFNKEIDQKTGFITRSILCMPIVGV-EGILGVVQVVNKK 379
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSK 401
FT D S+F F ++C L + T++ + L+ + D
Sbjct: 380 RGGHFTSTDESLFRTFCVYCALALRFTKVQKRMQSTRLLNNCFLKMIQLQVKPCIHD--- 436
Query: 402 LCQDEIPSAETYNLYSFQFHDFDLTDEDTCRAT---LRMFLQCELVEKFHIPYDVLCRWI 458
+ + +++ F + + ED + L MFLQ L++ P + +I
Sbjct: 437 IITYNVANSQVVIPMDFDHFGWHINTEDHPKMPQYILYMFLQ--LIKNTLHPERCI-HYI 493
Query: 459 LSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGT 518
LSVKK YR YHN+ HA NV M+ +LK +++F ++ EI L++A LCHD+DH G
Sbjct: 494 LSVKKFYRRNPYHNFEHAFNVVHCMYLILKRN-IKQF-TETEIKALMIAALCHDVDHPGF 551
Query: 519 NNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAI 578
N F + + LA LY S +E+H + +++L + N + LS +Y+ + ++ AI
Sbjct: 552 TNNFLELSNNDLANLYENSCLENHQYYVAMLLL--DHNKVLTHLSKEEYEVLRTEIKQAI 609
Query: 579 LSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAK 638
++TD +YF + ++ + FDW + + L G MM D+S + KP+ V RI
Sbjct: 610 IATDPLVYFANQINLEKICNTHSFDWGNETHRYYLKGTMMMVADLSGMCKPFLVSKRITD 669
Query: 639 LVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
+ E + QGDLEK ++ P++MMDR+K + +P+ QV FI T+ LP +L+ P
Sbjct: 670 NLYAECYLQGDLEK-EMGLCPLSMMDRDKSNFIPEDQVTFITTVILPCLDILAQLLP 725
Score = 54.4 bits (125), Expect = 1e-05
Identities = 25/51 (49%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTES 101
Y +FN EID +TG+ T ILCMPI EG ++GV Q++NK G H T +
Sbjct: 338 YKDARFNKEIDQKTGFITRSILCMPIVGVEG-ILGVVQVVNKKRGGHFTST 387
>UniRef50_A2EIP4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1334
Score = 203 bits (495), Expect = 2e-50
Identities = 120/394 (30%), Positives = 203/394 (51%), Gaps = 10/394 (2%)
Query: 324 LLCMPIVNANKDVIGVAQL-IN-KFTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQ 381
+ C+P++++ +GV ++ N K DV + E F++F + I +M E A
Sbjct: 939 ICCLPLMSSEAATLGVIEISCNWKILSEDVKLLECFSVFASVSIEIFRMKEVA----TLG 994
Query: 382 KVALECLSYHATASAEDTSKLCQD-EIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQ 440
+ A E S+ A + TSK+ I ++ ++ +F+ D + +F
Sbjct: 995 EAASEMKSWIADNELQLTSKIPNKLTINMSKLSSVLMVKFNAPDWDGIGLIKVVYAIFDI 1054
Query: 441 CELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLE 500
++ + F + + L R++ ++ NY+ V YHNWRHA++V Q + + +S E
Sbjct: 1055 FDINQTFGVTNERLFRFLSEIRDNYKKVPYHNWRHAVDVMQFVAYQILVSGCNTILSKFE 1114
Query: 501 ILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIF 559
I +LVACLCHD+ H G NAF K E+PL +L+ + S ME HH + IL+ E NIF
Sbjct: 1115 IFAILVACLCHDVGHDGFTNAFNEKAETPLGLLFKNQSVMETHHCSVSIGILSKEECNIF 1174
Query: 560 QALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMT 619
L P +YK++ ++ IL+TD+A +F + VDNGEFD Q E ++
Sbjct: 1175 SKLQPNEYKNMWILIIRLILATDMAKHFDILKDINQRVDNGEFDLQKNENDRYSFLEILI 1234
Query: 620 AC-DVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGF 678
C DVS +++P+E+ ++ ++ +EFF QGDLE+ + + DR D+ P+ Q+GF
Sbjct: 1235 KCGDVSNVSRPFELANKWCDVLCEEFFRQGDLEQASGMEYTSPLNDRAHLDK-PKSQIGF 1293
Query: 679 IDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
+CLPL++ + P + N +W+
Sbjct: 1294 YTAVCLPLFQTAAKIMPKLQCNVDQVQSNLAQWK 1327
Score = 55.6 bits (128), Expect = 5e-06
Identities = 39/148 (26%), Positives = 70/148 (47%), Gaps = 12/148 (8%)
Query: 292 ARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINKFTEG-- 349
A+S +NI D R + R+LLC+PI N ++ GV ++INK +G
Sbjct: 468 AQSGDIVNIKDAYADSRFDRSVDLATGFTTRSLLCIPIENNRGEITGVTEMINKLNDGLF 527
Query: 350 ---DVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQD- 405
D+ + AF +FCG+ I N ++Y+ + L + + +E ++ +A +K+ ++
Sbjct: 528 DDDDIKMLLAFNVFCGISIDNARLYKASLDLTRQLRSFIE-MTASLNTTANSLNKILEEI 586
Query: 406 -----EIPSAETYNLYSFQFHDFDLTDE 428
EI +A L+ D L +E
Sbjct: 587 LQNIKEIVNASRVTLFLIDEVDNSLKEE 614
Score = 44.4 bits (100), Expect = 0.013
Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK-TDG 95
Y +F+ +D TG+ T +LC+PI N G++ GV ++INK DG
Sbjct: 480 YADSRFDRSVDLATGFTTRSLLCIPIENNRGEITGVTEMINKLNDG 525
Score = 42.7 bits (96), Expect = 0.040
Identities = 17/79 (21%), Positives = 45/79 (56%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F D+++ + FCGI I NA+L+++S+ ++ + + + S+ ++L ++ +I
Sbjct: 527 FDDDDIKMLLAFNVFCGISIDNARLYKASLDLTRQLRSFIEMTASLNTTANSLNKILEEI 586
Query: 210 MTEARDLLKCERCAVFILD 228
+ ++++ R +F++D
Sbjct: 587 LQNIKEIVNASRVTLFLID 605
Score = 35.9 bits (79), Expect = 4.6
Identities = 14/33 (42%), Positives = 22/33 (66%)
Query: 201 NLECLVTKIMTEARDLLKCERCAVFILDTDHCE 233
+++ L+ IM A LL CERC++F++D H E
Sbjct: 410 DIDTLLPTIMNHATKLLSCERCSLFLVDAAHNE 442
>UniRef50_UPI000065E700 Cluster: Cone cGMP-specific 3',5'-cyclic
phosphodiesterase subunit alpha' (EC 3.1.4.35) (cGMP
phosphodiesterase 6C).; n=1; Takifugu rubripes|Rep: Cone
cGMP-specific 3',5'-cyclic phosphodiesterase subunit
alpha' (EC 3.1.4.35) (cGMP phosphodiesterase 6C). -
Takifugu rubripes
Length = 937
Score = 201 bits (491), Expect = 6e-50
Identities = 87/189 (46%), Positives = 126/189 (66%), Gaps = 1/189 (0%)
Query: 414 NLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNW 473
NLYSF F DF +++ D +A +RMF + +VEKF +P + L RW+ +V+K YR + YHNW
Sbjct: 584 NLYSFAFSDFPVSEFDLIKAGIRMFFELGVVEKFKVPAETLTRWMYTVRKGYRAITYHNW 643
Query: 474 RHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTES-PLAI 532
RH NV TMF +L+TGK+ ++ SDL+ ++ A CHD+DHRGTNN +QTK + PLA
Sbjct: 644 RHGFNVGHTMFCLLQTGKLRKYYSDLDAFAMVAAAFCHDIDHRGTNNLYQTKRSAHPLAK 703
Query: 533 LYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSK 592
L+ TS ME HH + ++ E NIF L R ++ V H+ + I++TDLA+YFKK++
Sbjct: 704 LHGTSIMERHHLEYSKTLMGEEVLNIFCNLQKRQFEHVQHLFDVCIIATDLALYFKKRTM 763
Query: 593 FLELVDNGE 601
F +V+ E
Sbjct: 764 FQNIVNATE 772
Score = 116 bits (279), Expect = 3e-24
Identities = 54/113 (47%), Positives = 76/113 (67%)
Query: 616 MMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQ 675
MMMT CD+SAI KPWEVQ ++A +VA EF++QGDLE+ L+QQPI MMDR ++LP+MQ
Sbjct: 824 MMMTGCDLSAITKPWEVQSKVALMVAAEFWEQGDLERSVLDQQPIPMMDRNCAEQLPKMQ 883
Query: 676 VGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKVDMGLTWIDHD 728
GFID +C +YK S + P+ G +NR W +LA+ + + I+ +
Sbjct: 884 CGFIDFVCSFVYKEFSRFHKEIQPMFDGLNNNRSHWNELAQVYEAKIKAIEDE 936
Score = 50.8 bits (116), Expect = 2e-04
Identities = 29/88 (32%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Query: 142 LSHSGSKEFSSRDVEVFRRYLTFCG-IGIQNAQLFESSVLEYKRNQILLALARSIFEEQS 200
L+ G+ F++ D ++F++Y+ F I +Q+ + +V E +R+Q+LL A +FEE +
Sbjct: 190 LNKIGADAFTAEDDQLFQKYMNFAQVITLQHHTAYMFNV-ESRRSQVLLWSASKVFEELT 248
Query: 201 NLECLVTKIMTEARDLLKCERCAVFILD 228
++E K + R L+CER +V +LD
Sbjct: 249 DIERQFHKALYTVRTYLQCERYSVGLLD 276
Score = 46.8 bits (106), Expect = 0.002
Identities = 22/87 (25%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Query: 321 VRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENAC 375
++ +L +PIVN ++++G+A N+ F E D I EA F G + N Y+
Sbjct: 405 IKNVLSLPIVNKKEEIVGIATFFNRKDGKPFDEHDEQITEALTQFLGWSVLNCDTYDRLN 464
Query: 376 KLMAKQKVALECLSYHATASAEDTSKL 402
++ ++ +A E L Y ++++ +
Sbjct: 465 RMEHRKDIAQEMLMYQTKCTSDELQSI 491
>UniRef50_Q6S996 Cluster: Class I phosphodiesterase PDEB1; n=21;
Trypanosomatidae|Rep: Class I phosphodiesterase PDEB1 -
Leishmania major
Length = 940
Score = 200 bits (488), Expect = 1e-49
Identities = 143/461 (31%), Positives = 223/461 (48%), Gaps = 36/461 (7%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLIN 344
IA VA S NI D R N SA + G RT +LC PI N +V+ V QL+N
Sbjct: 474 IAGTVAESGVGENIMDAYADSRFN--SAVDRQLGYRTQSILCEPIT-LNGEVLAVVQLVN 530
Query: 345 K---------FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAK-QKVALECLSYHATA 394
K FT D F+ F++F G+ I+N+ + E A + ++L+ S A
Sbjct: 531 KLGDDGSVTCFTPMDRETFQVFSLFAGISINNSHLLEFAVNAGREAMTLSLQRNSITAQR 590
Query: 395 SAEDTSKLC-----QDEIPSAETYNLYSFQFHDFDLTD---------EDTCRATLRMFLQ 440
+ + + ++ + S + Y F F+L + + +
Sbjct: 591 APKSVKVIAVTPEEREAVMSIDFGGAYDFTSPGFNLFEVREKYSEPMDAAAGVVYNLLWN 650
Query: 441 CELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLE 500
L EKF L +IL ++ YR V YHN+ H ++V QT+ L TGK +++LE
Sbjct: 651 SGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELE 710
Query: 501 ILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS----TSTMEHHHFDQCVMILNSESN 556
LLV L HDLDH G NN+F KT+SPL IL S S +E HH + IL+ +
Sbjct: 711 CYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAA 770
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGM 616
++F+ LS +D + +L+TD+A + S+F EL +G F+ + L+
Sbjct: 771 DVFEGLSGQDVAYAYRALIDCVLATDMAKHADALSRFTELATSG-FEKDNDTHRRLVMET 829
Query: 617 MMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQV 676
++ A DVS + KP+E A V +EF+ QGD+EK + + + M DR K +EL + Q+
Sbjct: 830 LIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEK-EKGVEVLPMFDRSKNNELARGQI 888
Query: 677 GFIDTICLPLYK-VLSDTFPWMTPLRTGTADNRRRWQDLAE 716
GFID + ++ ++ + F M NR +WQ++ +
Sbjct: 889 GFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILD 929
Score = 47.2 bits (107), Expect = 0.002
Identities = 21/40 (52%), Positives = 28/40 (70%), Gaps = 1/40 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
+F+ +D TGY T ILC+PI +EG +V VAQ+INK D
Sbjct: 319 RFHRSVDKVTGYHTRTILCLPIA-FEGTIVAVAQLINKLD 357
Score = 45.6 bits (103), Expect = 0.006
Identities = 23/56 (41%), Positives = 34/56 (60%), Gaps = 3/56 (5%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK--TDGEHTTESTLD 104
Y +FNS +D + GY+T+ ILC PI G+V+ V Q++NK DG T + +D
Sbjct: 491 YADSRFNSAVDRQLGYRTQSILCEPI-TLNGEVLAVVQLVNKLGDDGSVTCFTPMD 545
>UniRef50_A2EY05 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 922
Score = 199 bits (485), Expect = 3e-49
Identities = 103/398 (25%), Positives = 199/398 (50%), Gaps = 12/398 (3%)
Query: 321 VRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENAC 375
++++L PI+N +DV+ QL NK F++ D+ I F+ F + N Q
Sbjct: 523 IKSVLSYPILNNEEDVVAAIQLSNKEDQNQFSQTDIKILSLFSKFISFVVENDQFKTQEN 582
Query: 376 KLMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATL 435
+ + + +S E+ + ++ +++ N++ +F+ D
Sbjct: 583 NSLQQDDEVSQFIS-----KDEENKFIIPSKLENSKISNIFDLEFYTIDYIGTGLFEIAF 637
Query: 436 RMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERF 495
++F + ++EKF I + +++L +++NY YHNW HA++V Q + +K
Sbjct: 638 KIFNEFGILEKFQISSSLFLKFLLKLRRNYNNPPYHNWTHAIDVLQYVSYEIKLTNSHNH 697
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSE 554
+ E+L +LVA LCHD+ H+G NNA+ ++P IL+ TS ME H + IL +
Sbjct: 698 LKSQELLSVLVAALCHDVGHQGFNNAYNINVKTPFGILFKDTSVMETFHCAMAIKILQED 757
Query: 555 SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLC 614
N+F +L+ D +V + IL+TD+A +FK + + + + D +++ +
Sbjct: 758 DTNLFYSLNDNDLSNVWSWIIHLILATDMAKHFKLIKEMNDTISSRNLDMESENDRLCCM 817
Query: 615 GMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQM 674
M+M D+S +++P+ + + ++ DEF+ QGD+EK +M RE +++ +
Sbjct: 818 EMIMKVADISNVSRPFFIADKWCDVLQDEFWRQGDMEKQHELSYSSPLMSREGQNK-AKG 876
Query: 675 QVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
Q+GF +C+PLY +++ FP + N + W+
Sbjct: 877 QIGFYKAVCIPLYSLVARIFPELNKSLDSVNANLKEWE 914
>UniRef50_A2G2M9 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1136
Score = 195 bits (475), Expect = 5e-48
Identities = 118/436 (27%), Positives = 220/436 (50%), Gaps = 10/436 (2%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA + S+ I D R N M ++L+ +P++ ++ VIGVA+++NK
Sbjct: 673 IAATAVKQKISIVIQDAYHDPRFNKMIDFHTGFKTKSLIAVPVITSDGTVIGVAEMLNKQ 732
Query: 346 ---FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKL 402
FT+ D ++ E+F+ F L + ++ + K A+ +++ + + T KL
Sbjct: 733 EGIFTQSDQTLLESFSTFAALLLEKRRLKDITEKGTAQIEMSKWIGEFERSTYTTPT-KL 791
Query: 403 CQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVK 462
+P A+ L S F D + +F L+E+F I D+ ++ ++
Sbjct: 792 ---RVPEAKQDVLKSLDFFAIDWNGIGLFQIAFFVFNDFGLLERFQITNDLFFTFLYRLR 848
Query: 463 KNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAF 522
+ Y YHNW HA++V Q + ++ + ++ E+L + VA LCHD H+G NNAF
Sbjct: 849 EAYNEPPYHNWIHAIDVLQYISYQVRITNSHKILTQFELLAVCVAALCHDAGHQGLNNAF 908
Query: 523 QTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILST 581
E+PL IL+ S ME H + IL+ N+F +L+ ++ + + IL+T
Sbjct: 909 NVNAETPLGILFKDQSVMETFHCTVAIRILSQPETNLFHSLNTKELTVIWKWIIHLILAT 968
Query: 582 DLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVA 641
D+A +FK + E ++ G + + + + + ++M D+S +++P++ + ++++
Sbjct: 969 DMAFHFKLIKQGNEALEAGVINLKEEAHRLMCMELVMKVSDISNVSRPFKYADKWCEVLS 1028
Query: 642 DEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLR 701
+EF+ QGD EK +M+RE +++ P+ QVGF + +CLPLY +++ FP +T
Sbjct: 1029 EEFWRQGDKEKELGLPYSGPLMNREGQNK-PKGQVGFYNFVCLPLYTLIARIFPELTVNL 1087
Query: 702 TGTADNRRRWQDLAEK 717
N +W L E+
Sbjct: 1088 ESVKSNLAQWVKLVEE 1103
Score = 47.2 bits (107), Expect = 0.002
Identities = 20/50 (40%), Positives = 35/50 (70%), Gaps = 1/50 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHT-TESTL 103
+FN ID TG+KT+ ++ +P+ +G V+GVA+++NK +G T ++ TL
Sbjct: 694 RFNKMIDFHTGFKTKSLIAVPVITSDGTVIGVAEMLNKQEGIFTQSDQTL 743
Score = 44.4 bits (100), Expect = 0.013
Identities = 20/52 (38%), Positives = 35/52 (67%), Gaps = 2/52 (3%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLDHNY 107
F++ ID +T YKT+ +L +P+ N +V+ V Q+IN+ DG+ +++ D NY
Sbjct: 528 FDNAIDLQTQYKTKTLLSVPVMNNRLEVIAVLQMINRKDGQPFSQT--DFNY 577
Score = 41.5 bits (93), Expect = 0.093
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query: 294 SNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK-----FTE 348
S + +N+++ + +N + +TLL +P++N +VI V Q+IN+ F++
Sbjct: 513 SKEIINLTEAYEDPNFDNAIDLQTQYKTKTLLSVPVMNNRLEVIAVLQMINRKDGQPFSQ 572
Query: 349 GDVSIFEAFAIFCGLGIHNTQMY 371
D + + F+I GL + N QMY
Sbjct: 573 TDFNYMKIFSIMFGLLLDNQQMY 595
>UniRef50_A2ENJ2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1087
Score = 194 bits (473), Expect = 8e-48
Identities = 147/631 (23%), Positives = 282/631 (44%), Gaps = 34/631 (5%)
Query: 81 GDVVGVAQIINKTDGEHTTESTLDHNYEPRPGQITRGPVASHWYSLYYFGNQRLYTYLRR 140
G V I+N D + D + + + G TR V ++ F N+ +
Sbjct: 445 GYTVTTGNIVNIPDAY--ADPRFDQSVDKKTGYHTRNLV-----TVPIFNNRNDIVGVTE 497
Query: 141 KLSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQS 200
++ F D+++ + FCGI + NA+L+++S+ ++ + + L+ S+ + +S
Sbjct: 498 MINKIDGDCFDDEDLKMVVAFNVFCGISLDNARLYQASLDLTRQLRSFVDLSASLNKTKS 557
Query: 201 NLECLVTKIMTEARDLLKCERCAVFILDTDHCESSHLERIVQXXXXXXXXXXXXXXXXXX 260
E ++ +I+++A+ ++ R +F+ + D + E I
Sbjct: 558 INE-VINEILSQAKVVVHAARATIFLSEQDG-SLTPFESIGDPINHGTLFASQMKQYMKT 615
Query: 261 XXXXXTRFHTVFELGAPRRPHDALPAIA-----LAVARSNKSLNISDVEQWLRDNNMSAG 315
T V E+ A + +D L A ++ S +S + S L D N S+
Sbjct: 616 TIFNETE---VQEIVACEQSNDPLAATTSQKGGTSLKMSKRSSSSSSRVSVLFDGNSSSS 672
Query: 316 ENSAGV--------RTLLCMPIVNANKDVIGVAQLIN--KFTEGDVSIFEAFAIFCGLGI 365
S +++ ++ + IGV ++ + K D + + FA+F + +
Sbjct: 673 MTSTNSVSSAMKNGESIVIFSLLTTSGKFIGVMEISSNSKILMEDAKLIDCFAVFAAISL 732
Query: 366 HNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDL 425
+++ E A L +K + + A KL DE + + F +D
Sbjct: 733 ERSELREIAT-LGTIEKGIKDWIKPEERADYNVPEKLKMDE----KVFICREFDAQAYDN 787
Query: 426 TDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFA 485
+ +F +L+ +F I + R++ ++ Y+ V YHNWRHA++V Q +
Sbjct: 788 NPIGWFQVVFGIFNHFDLLREFDISNEKFFRFLSAISATYKKVPYHNWRHAVDVTQYVTF 847
Query: 486 MLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHF 544
L+T + ++ +I LLVA +CHD +H G N + K E+PL IL+ + S ME HH
Sbjct: 848 ELETSGIVSKLTKFDIFALLVAAICHDANHDGFTNVYNVKAETPLGILFKNQSVMETHHC 907
Query: 545 DQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDW 604
+ +++ E NIF L+ YK + + IL+TD+A +F + ++D G+
Sbjct: 908 AMAISVISKEETNIFAKLNAEQYKKIWTTIINLILATDMAKHFTFLKEINGIMDEGKLSI 967
Query: 605 QAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMD 664
+ +++ D+S +++P+E+ + ++ +EFF QGDLE Q Q + D
Sbjct: 968 DNPDDVSYYLELILKCADISNVSRPFELADKWCDVLCEEFFRQGDLEMAQGMQYTSDLND 1027
Query: 665 REKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
R ++ P+ Q+GF +CLPL++ + P
Sbjct: 1028 RSHLNK-PKSQIGFYTFVCLPLFEAAARAMP 1057
Score = 48.0 bits (109), Expect = 0.001
Identities = 19/46 (41%), Positives = 30/46 (65%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
Y +F+ +D +TGY T ++ +PI N D+VGV ++INK DG+
Sbjct: 460 YADPRFDQSVDKKTGYHTRNLVTVPIFNNRNDIVGVTEMINKIDGD 505
>UniRef50_A2ERL4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1180
Score = 188 bits (458), Expect = 6e-46
Identities = 103/376 (27%), Positives = 192/376 (51%), Gaps = 6/376 (1%)
Query: 323 TLLCMPIVNANKDVIGVAQLINKFT--EGDVSIFEAFAIFCGLGIHNTQMYENACKLMAK 380
T++C+P+VN ++GV QL +T DV + +++A+F L I + A +
Sbjct: 665 TIVCIPLVNNENTILGVIQLTCPWTVIPEDVKMLKSYAVFASLIIERQNLKGIAEFGQDE 724
Query: 381 QKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQ 440
++ + E SKL E N+++ +F+ + + +F
Sbjct: 725 VEMNTWMTKEEKHSMTEIPSKLIIPE--DVLKNNVFTIKFNSLEWDGIGHFKVLFAIFHY 782
Query: 441 CELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLE 500
+ + + I + R++ +++ Y+ V YHNWRHA++V Q + + +E+ + E
Sbjct: 783 FDFFQIYKITNEKFFRFLYAIRSMYKKVPYHNWRHAVDVTQFVTYQIMISGLEKVFTKFE 842
Query: 501 ILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNIF 559
+ L+VA +CHD +H G N + K E+PL ILY S ME HH + I++ E N+
Sbjct: 843 LFSLVVAAICHDANHDGFTNIYNVKAETPLGILYKNQSVMETHHCSIAIQIMSHEETNLL 902
Query: 560 QALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMT 619
AL+ +Y ++ ++ IL+TD+A +F+ +F ++ D G+F Q + + +L M++
Sbjct: 903 AALNQDEYIEIWSLIIQYILATDMARHFEILKRFNDIYDGGDFTMQRHDHRVMLLYMILK 962
Query: 620 ACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFI 679
D+S +++P+E+ R ++ +EFF QGDLE+ Q + DR D+ + Q+GF
Sbjct: 963 CGDISNVSRPFELADRWCDVLCEEFFRQGDLEQAQGMAYTSDLNDRSHLDK-AKSQIGFY 1021
Query: 680 DTICLPLYKVLSDTFP 695
+ LP+++ P
Sbjct: 1022 TYVTLPMFQAAGKAVP 1037
Score = 58.0 bits (134), Expect = 1e-06
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Query: 292 ARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK-----F 346
A + LNI D R N E T+L +PIVN ++IGV ++INK F
Sbjct: 425 ATTGAILNIPDAYSDPRFNKQIDIETGFRTNTILSVPIVNNRGEIIGVTEMINKKSGLLF 484
Query: 347 TEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSK 401
+ D+ + AF +FCG+ + N ++Y+ + L + + E S S++ T K
Sbjct: 485 DDEDIRMMTAFNVFCGISLDNAKLYQASLDLSKQLTIFTEMSSAIKEDSSDQTLK 539
Score = 50.0 bits (114), Expect = 3e-04
Identities = 20/45 (44%), Positives = 30/45 (66%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDG 95
Y +FN +ID TG++T IL +PI N G+++GV ++INK G
Sbjct: 437 YSDPRFNKQIDIETGFRTNTILSVPIVNNRGEIIGVTEMINKKSG 481
Score = 39.1 bits (87), Expect = 0.49
Identities = 20/81 (24%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F D+ + + FCGI + NA+L+++S+ K+ I ++ +I E+ S + + I
Sbjct: 484 FDDEDIRMMTAFNVFCGISLDNAKLYQASLDLSKQLTIFTEMSSAIKEDSS--DQTLKSI 541
Query: 210 MTEARDLLKCERCAVFILDTD 230
+ A++ L ++I ++D
Sbjct: 542 IMNAKNTLGASGAVLYIYNSD 562
>UniRef50_A2DNV4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1023
Score = 183 bits (445), Expect = 2e-44
Identities = 102/390 (26%), Positives = 198/390 (50%), Gaps = 12/390 (3%)
Query: 328 PIVNANKDVIGVAQLINKF--TEGDVSIFEAFAIFCGLGIHNTQMYENA--CKLMAKQKV 383
P+ + ++ VIG+ + K T + + E++ F + I Q+ + A +L+ +
Sbjct: 636 PLTSQDRVVIGIVEFETKLPLTTEHIKLLESYCTFASMAIERDQLQKIAKSSQLLIHEH- 694
Query: 384 ALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCEL 443
+ + + L DE + + L F FD R +F + +L
Sbjct: 695 --QFMKNEEKDKFTTPANLVLDEESEKQVFTL-GFDAQKFDGFSH--YRVMWAIFTRFDL 749
Query: 444 VEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILG 503
+ +F++ + ++ V ++Y V YHN RHA++V Q + + GK+++ ++ E+
Sbjct: 750 LREFNVTNEKFFSFLTEVSESYNKVPYHNRRHAVDVTQFVAYEIIIGKIDKILTKEELFC 809
Query: 504 LLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQAL 562
LL+AC+CHD++H G N + K E+PL IL+ + S ME HH + + I+ +E +N+F
Sbjct: 810 LLIACICHDINHDGFTNVYNVKAETPLGILFKNQSVMETHHCEVTIGIMTNEMSNVFACF 869
Query: 563 SPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACD 622
+ Y + ++ T IL TD+ ++ +F EL+D G D+ + + L +++ D
Sbjct: 870 EGQQYSKMWQMLFTLILGTDMFHHYTIIKQFNELLDKGPLDYSDDQNRLKLMQILLKCGD 929
Query: 623 VSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTI 682
+S +++P+++ + ++ +EFF QGDLE+ Q + + DR D+ P+ Q+GF +
Sbjct: 930 ISNVSRPFKIADKWCDVLCEEFFRQGDLEQAQGMEYTSNLNDRAHLDK-PKSQIGFYKFV 988
Query: 683 CLPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
CLPL++V P + + N + W+
Sbjct: 989 CLPLFEVAERAIPELGVNKQSILINLKEWE 1018
Score = 57.2 bits (132), Expect = 2e-06
Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 4/99 (4%)
Query: 292 ARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----FT 347
AR+ + +NI++ R +N E R +L +PI N+N +V GV Q+INK F
Sbjct: 402 ARTGQIVNITNAYNDPRFDNSVDIETGFRTRNILGVPIYNSNGEVTGVTQMINKKDGNFI 461
Query: 348 EGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
E D+ I + F +FCG+ + N +++ + L K +E
Sbjct: 462 EDDIKIMKCFNVFCGISLDNVKLFNVSTNLANHLKKFVE 500
Score = 48.8 bits (111), Expect = 6e-04
Identities = 30/76 (39%), Positives = 45/76 (59%), Gaps = 4/76 (5%)
Query: 21 DSQLR-PKTISTSGMHTPIPGKIPHKLTAIKYITIQFNSEIDARTGYKTELILCMPICNY 79
DS++R P + G +T G+I + A Y +F++ +D TG++T IL +PI N
Sbjct: 386 DSEIRIPMSRGIVG-YTARTGQIVNITNA--YNDPRFDNSVDIETGFRTRNILGVPIYNS 442
Query: 80 EGDVVGVAQIINKTDG 95
G+V GV Q+INK DG
Sbjct: 443 NGEVTGVTQMINKKDG 458
Score = 35.1 bits (77), Expect = 8.1
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F D+++ + + FCGI + N +LF S + A F + N LV ++
Sbjct: 460 FIEDDIKIMKCFNVFCGISLDNVKLFNVST-NLANHLKKFVEAADTFTKSENKNALV-EL 517
Query: 210 MTEARDLLKCERCAVFILDTD 230
+ A D+ + R + D D
Sbjct: 518 LESAADICQASRATMLSYDVD 538
>UniRef50_Q7PQX7 Cluster: ENSANGP00000010843; n=6; Coelomata|Rep:
ENSANGP00000010843 - Anopheles gambiae str. PEST
Length = 547
Score = 173 bits (422), Expect = 1e-41
Identities = 103/305 (33%), Positives = 160/305 (52%), Gaps = 9/305 (2%)
Query: 397 EDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCR 456
E K DE+ +A L +F ++++ D D MF++ L+EKF+IP L
Sbjct: 30 ETCDKTLSDEVKAA--LRLPAFDSYEWE--DWDVIHLMQTMFVELNLLEKFNIPIVTLRE 85
Query: 457 WILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
W+ V K+Y V +HN+RH VAQ M+ + + + + +LE+L LLV+C+CHDLDH
Sbjct: 86 WLYEVYKHYNDVPFHNYRHCFCVAQMMYTIAWHTNLVQRLGELEVLVLLVSCICHDLDHP 145
Query: 517 GTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVE 575
G NN +Q + LA+ Y+ S +E+HH +L NIF+ +S YKDV +
Sbjct: 146 GYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFRNMSKEMYKDVREGII 205
Query: 576 TAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHR 635
IL+TD+A + + ++F E EFD+ + LLC +++ D+S A+P +V
Sbjct: 206 RCILATDMARHNEILTQFQEATP--EFDYSNKVHTNLLCMVLIKVADISNEARPMDVAEP 263
Query: 636 IAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
+ EFF Q EK + MD +K + P QV FI + LPL++ L + P
Sbjct: 264 WVDRLLQEFFAQSAAEKSE-GLPVTPFMDPDKVSK-PGSQVRFIGLVLLPLFEALGELLP 321
Query: 696 WMTPL 700
+T L
Sbjct: 322 ELTDL 326
>UniRef50_UPI0000D577EC Cluster: PREDICTED: similar to CG32648-PA;
n=2; Coelomata|Rep: PREDICTED: similar to CG32648-PA -
Tribolium castaneum
Length = 938
Score = 172 bits (419), Expect = 3e-41
Identities = 100/297 (33%), Positives = 156/297 (52%), Gaps = 5/297 (1%)
Query: 397 EDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCR 456
++ + +C+ ++ A L + F DE+ +M+L +L KF I + L
Sbjct: 173 QNFANICEAQVSDAIRQWLRTPTFDARPWEDEELLLLLQQMYLDYDLCSKFAIDINTLRN 232
Query: 457 WILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
++ KNY V +HN+RH VAQ M+A+ + + + DLE+L LL +C+CHDLDH
Sbjct: 233 FLYEAYKNYNDVPFHNFRHCFCVAQMMYAISWSVDLPSKVGDLEVLILLTSCICHDLDHP 292
Query: 517 GTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVE 575
G NN +Q ++ LAI Y+ S +E+HH IL +E NIF++ D+K V +
Sbjct: 293 GYNNIYQINAKTELAIRYNDISPLENHHCSVAFRILENEDCNIFKSFKSEDFKTVREGII 352
Query: 576 TAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHR 635
IL+TD+A + + + F E+ N FD+ + LLC +++ D+S A+P +V
Sbjct: 353 RCILATDMARHNEILTNFREITPN--FDYNDKAHVNLLCMVLIKVSDISNEARPMDVAEP 410
Query: 636 IAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSD 692
+ EFF Q D EKL+ MDREK + P Q FI + LPL++ L D
Sbjct: 411 WLDRLLQEFFKQSDAEKLE-GLPVTPFMDREKITK-PSSQCSFIGFVLLPLFEALGD 465
>UniRef50_Q16VA1 Cluster: High-affinity cgmp-specific 3,5-cyclic
phosphodiesterase; n=1; Aedes aegypti|Rep: High-affinity
cgmp-specific 3,5-cyclic phosphodiesterase - Aedes
aegypti (Yellowfever mosquito)
Length = 1022
Score = 170 bits (414), Expect = 1e-40
Identities = 97/282 (34%), Positives = 149/282 (52%), Gaps = 5/282 (1%)
Query: 420 FHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNV 479
F ++ D D MF++ L+EKF IP + L W+ V K+Y V +HN+RH V
Sbjct: 54 FDSYEWEDWDVIHLMQTMFVELNLLEKFQIPRETLREWLYEVYKHYNDVPFHNYRHCFCV 113
Query: 480 AQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TST 538
AQ M+A+ + + + +LE+L LLV+C+CHDLDH G NN +Q + LA+ Y+ S
Sbjct: 114 AQMMYAITWHTNLVQRLGELEVLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISP 173
Query: 539 MEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVD 598
+E+HH +L NIF+ +S YKDV + IL+TD+A + + ++F E
Sbjct: 174 LENHHCSIAFRLLEHPDCNIFRNMSKDLYKDVREGIIRCILATDMARHNEILTQFQEATP 233
Query: 599 NGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQ 658
FD+ + LLC +++ D+S A+P +V + EFF Q EK +
Sbjct: 234 --VFDYNNKVHTNLLCMVLIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSE-GLP 290
Query: 659 PIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPL 700
MD +K + P QV FI + LPL++ L + P +T L
Sbjct: 291 VTPFMDPDKVSK-PGSQVRFIGLVLLPLFEALGELLPELTDL 331
>UniRef50_UPI00015B464B Cluster: PREDICTED: similar to
ENSANGP00000010843; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010843 - Nasonia
vitripennis
Length = 801
Score = 170 bits (413), Expect = 2e-40
Identities = 94/273 (34%), Positives = 148/273 (54%), Gaps = 5/273 (1%)
Query: 427 DEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAM 486
DE+ MF + EL +KF+IP L +I V NY V +HN+RH VAQ ++ +
Sbjct: 503 DEELLLMLQTMFFELELPQKFNIPLSTLRNFIYEVYNNYNEVPFHNFRHCFCVAQMLYII 562
Query: 487 LKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFD 545
+ + + DLE+L L+V+C+CHDLDH G NN +Q + LA+ Y+ S +E+HH
Sbjct: 563 TGSVNTKSRIGDLEVLVLIVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCS 622
Query: 546 QCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQ 605
IL + NI +L P Y+ V + IL+TD+A + + ++F + V +FD+
Sbjct: 623 VAFHILEAPECNILASLQPETYRIVREGIIRCILATDMARHNEILAQFTDAVP--DFDYS 680
Query: 606 AQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDR 665
++ LL +++ D+S A+P +V + EFF Q D EKL+ MDR
Sbjct: 681 SKVHINLLSMVLIKVADISNEARPMDVAEPWLDSLLQEFFKQSDAEKLE-GLPVTPFMDR 739
Query: 666 EKKDELPQMQVGFIDTICLPLYKVLSDTFPWMT 698
+K + P Q FI + LPL+++L + FP +T
Sbjct: 740 DKVTK-PSSQCSFIGLVLLPLFEILGELFPELT 771
>UniRef50_Q9VYJ0 Cluster: CG32648-PA; n=3; Coelomata|Rep: CG32648-PA
- Drosophila melanogaster (Fruit fly)
Length = 963
Score = 169 bits (411), Expect = 3e-40
Identities = 94/282 (33%), Positives = 148/282 (52%), Gaps = 5/282 (1%)
Query: 420 FHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNV 479
F ++ +D D MF++ +EKF IP D L W+ V K+Y V +HN+RH V
Sbjct: 60 FDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEVPFHNFRHCFCV 119
Query: 480 AQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TST 538
AQ M+A+ + + + DLE L LLV+C+CHDLDH G NN +Q + LA+ Y+ S
Sbjct: 120 AQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISP 179
Query: 539 MEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVD 598
+E+HH +L NIF+ S + ++ + IL+TD+A + + ++F+E+
Sbjct: 180 LENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITP 239
Query: 599 NGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQ 658
FD+ + LLC +++ D+S A+P +V + EFF Q EK +
Sbjct: 240 --IFDYSNRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSE-GLP 296
Query: 659 PIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPL 700
MD +K + P QV FI + LPL++ L + P +T L
Sbjct: 297 VTPFMDPDKVSK-PGSQVRFIGLVLLPLFEALGELVPELTEL 337
>UniRef50_Q23917 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase
regA; n=2; Dictyostelium discoideum|Rep:
3',5'-cyclic-nucleotide phosphodiesterase regA -
Dictyostelium discoideum (Slime mold)
Length = 793
Score = 168 bits (409), Expect = 5e-40
Identities = 92/301 (30%), Positives = 159/301 (52%), Gaps = 4/301 (1%)
Query: 418 FQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPV-KYHNWRHA 476
++F F +++D + MF +L E F IP + L R+I++V YR +YHN+ HA
Sbjct: 433 WEFDVFKYSEDDLMPLLVDMFENFQLPEIFKIPIEKLQRFIMTVNALYRKNNRYHNFTHA 492
Query: 477 LNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST 536
+V QT++ L + ++++ L+I LL++C+CHDL+H G NN FQ ++ L++ Y+
Sbjct: 493 FDVTQTVYTFLTSFNAAQYLTHLDIFALLISCMCHDLNHPGFNNTFQVNAQTELSLEYND 552
Query: 537 -STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLE 595
S +E+HH IL + NI + L+ YK++ V IL+TD+ +F+ +KF
Sbjct: 553 ISVLENHHAMLTFKILRNSECNILEGLNEDQYKELRRSVVQLILATDMQNHFEHTNKFQH 612
Query: 596 LVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQL 655
++N FD +E ++++ ++ D+S IA+PW + + V+DEFF Q E +
Sbjct: 613 HLNNLPFDRNKKEDRQMILNFLIKCGDISNIARPWHLNFEWSLRVSDEFFQQSHYETI-C 671
Query: 656 NQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLA 715
MD+ K ++ FID + PL++ ++ L + NR WQ
Sbjct: 672 GYPVTPFMDKTKTTR-ARIAADFIDFVASPLFQSMAKFLKESQFLLKVISKNRENWQAYM 730
Query: 716 E 716
E
Sbjct: 731 E 731
>UniRef50_A2F9J4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1119
Score = 163 bits (395), Expect = 2e-38
Identities = 97/324 (29%), Positives = 160/324 (49%), Gaps = 10/324 (3%)
Query: 394 ASAEDTSKLCQDEIPSAETYNLYSFQ-FHDFDLTDEDTCRATLRMFLQCELVEKFHIPYD 452
++ E S + + P+ YS + F+ D+D L++F+ ++ K +P+
Sbjct: 788 STEERASFMSRASAPTRSDIEEYSDRLFNILSYNDDDRMIMILKLFVSQGVIRKLQVPFQ 847
Query: 453 VLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHD 512
L ++I S++ Y YHNW HA +V Q +F+ + G + ++++DLEI LL+A +CHD
Sbjct: 848 KLTQFICSLRSCYNVTPYHNWTHACDVMQFVFSCIIRGHLRQYLNDLEIFALLLAAICHD 907
Query: 513 LDHRGTNNAFQTKTESPLAILYSTS-TMEHHHFDQCVMILNSESNNIFQALSPRDYKDVM 571
+DH G NNAF K +PL ILY ME HH + +L ++I + + Y D
Sbjct: 908 VDHHGLNNAFHKKARTPLGILYEDKPVMEMHHCATAIRLLAMPEHDILEGI--ESYADKC 965
Query: 572 HVVE---TAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAK 628
H E IL+TD+ + + F E+ EFD + ++ + LL +++ A D+S +
Sbjct: 966 HFYEFFIKIILATDMEKHMQYIKDFEEVTK--EFDKRNEKHRLLLAQIVIKAGDLSNTTR 1023
Query: 629 PWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYK 688
++ +A + +EFF QGDLE +L + M DR K + QVGF PL
Sbjct: 1024 AFDTAAAMATNLMEEFFKQGDLES-KLGVEITPMCDRSKATHISCSQVGFYGFCASPLLT 1082
Query: 689 VLSDTFPWMTPLRTGTADNRRRWQ 712
L + N+R W+
Sbjct: 1083 ALGKFITSLADNTEQLEKNKRVWE 1106
>UniRef50_A7SVS5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 496
Score = 159 bits (386), Expect = 3e-37
Identities = 88/262 (33%), Positives = 148/262 (56%), Gaps = 6/262 (2%)
Query: 436 RMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERF 495
+M++ L+++F I L ++ V ++Y P +HN+RHA V Q M+ ++ ++
Sbjct: 190 QMYIDLGLLDEFKIERSKLQHFLFEVYRHYNPTPFHNFRHAFCVTQMMYGLIWLTEIFNK 249
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSE 554
++ ++L +L + LCHDLDH G NNA+Q + LA+ Y+ S +E+HH I+ +
Sbjct: 250 ITKQDLLIMLTSALCHDLDHPGYNNAYQINARTELALRYNDISPLENHHCAVAFDIMKQD 309
Query: 555 SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLC 614
+NI Q +S +K + + ILSTD+A + +KF EL+ +G F + + K +L
Sbjct: 310 KSNILQNVSAETFKKIREGMIKCILSTDMARHSDILNKFKELLKSG-FKFDDEAHKSMLM 368
Query: 615 GMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIA-MMDREKKDELPQ 673
+M+ DVS A+P +V + EFF Q D+EKL+ P+A MDR+K + P
Sbjct: 369 QIMIKVSDVSNEARPMDVAEPWLDCLLQEFFIQSDVEKLE--GLPVAPFMDRDKVTK-PS 425
Query: 674 MQVGFIDTICLPLYKVLSDTFP 695
Q+GFI + +PL++ L + FP
Sbjct: 426 AQIGFIKFVLVPLFEALGELFP 447
>UniRef50_A2EHB3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1213
Score = 159 bits (385), Expect = 4e-37
Identities = 105/422 (24%), Positives = 204/422 (48%), Gaps = 19/422 (4%)
Query: 322 RTLLCMPIVNANKDVIGVAQLI-----NKFTEGDVSIFEAFAIFCGLGIHNTQMYENACK 376
++L+C+PI+++++ V+G + KFT+ D+ + E++++F L + ++ +N +
Sbjct: 767 KSLICVPILSSDRVVMGAVLMRWKKSQQKFTQDDLKLLESYSVFLSLSLERFKL-KNIAQ 825
Query: 377 LMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLR 436
L + + +S +KL + E L F + +
Sbjct: 826 LGSLEVEMQNVMSNEERGEMRVPTKLLMSD---EECGALLLRNFESTEWKGMALFKVAFN 882
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFM 496
+F L +KF I ++ +K +Y PV YHN+ HA++ Q M ++ ++ +
Sbjct: 883 IFNTFNLFKKFKISASCFFSFLFEMKNSYLPVPYHNFTHAIDTMQFMAHVIILCGLKDVL 942
Query: 497 SDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSES 555
+ EIL LLVAC+CHD +H G +N + K ++PL+IL+ S +E HH + IL+ +
Sbjct: 943 TQKEILILLVACICHDANHDGFSNNYNYKAQTPLSILFKGQSVLETHHCSVSITILSKDE 1002
Query: 556 NNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELL-C 614
+ +F + V + +++TD++ +F + E + G W+ K LL
Sbjct: 1003 SALFNNFPDDEIASVWTLFIDLVMATDMSKHFDIVDEMREYLAMG-LTWKDHPKGRLLFM 1061
Query: 615 GMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQM 674
+++ A D+S + +E R A ++ +EFF QGDLE+ + + +R+ ++ +
Sbjct: 1062 KLLIKAADISNCVREFETADRWADVLCEEFFRQGDLERALGMEYDGPLHERQHLNK-QKS 1120
Query: 675 QVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKVDMGLTWIDHDTIDKPV 734
Q+GF ++ LPLY ++ P + T +N +W ++ D D + I+K
Sbjct: 1121 QLGFYKSVALPLYLLMERIEPGFSVFVTNVKNNMEKWAATKKEKD------DLERIEKEK 1174
Query: 735 EE 736
EE
Sbjct: 1175 EE 1176
Score = 51.2 bits (117), Expect = 1e-04
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 292 ARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----FT 347
A + LNI D R N + T+L +PI + K + GV ++INK FT
Sbjct: 545 ATKGEILNIKDAYDDPRFNRGTDLATGYRTLTILSVPIFDDKKGIRGVTEMINKLDGVFT 604
Query: 348 EGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEI 407
E D + + F +FCG+ I N ++Y + L Q + +S + A ++ KL ++ I
Sbjct: 605 EDDEKLIQIFNVFCGISIENARLYRASLDL-TMQLHSFRDIS-ASMAQSQTIKKLLEEII 662
Query: 408 PSAET 412
+ T
Sbjct: 663 KNTRT 667
Score = 43.6 bits (98), Expect = 0.023
Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Query: 162 LTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKIMTEARDLLKCER 221
LT I +N E S+ + KR + LL +A ++ Q ++ L+ IM+ A DL+K +R
Sbjct: 449 LTSAEIVEKNHMALEESLRQQKRLRSLLEVAETL-SGQLRMDVLIPNIMSRACDLVKADR 507
Query: 222 CAVFILDTDH 231
C++F+++ H
Sbjct: 508 CSLFLVNDSH 517
Score = 39.9 bits (89), Expect = 0.28
Identities = 19/46 (41%), Positives = 28/46 (60%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
+FN D TGY+T IL +PI + + + GV ++INK DG T +
Sbjct: 561 RFNRGTDLATGYRTLTILSVPIFDDKKGIRGVTEMINKLDGVFTED 606
>UniRef50_Q8I6Y6 Cluster: CGMP-specific phosphodiesterase; n=3;
Dictyostelium discoideum|Rep: CGMP-specific
phosphodiesterase - Dictyostelium discoideum (Slime
mold)
Length = 522
Score = 158 bits (384), Expect = 5e-37
Identities = 84/302 (27%), Positives = 158/302 (52%), Gaps = 6/302 (1%)
Query: 414 NLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNW 473
+++S F + + ++ + +F + L ++ ++ + ++ V +YR +H++
Sbjct: 212 DIFSINFSSWSKSKDNLIENGVLIFEESGLYKELNLSKSSILNFLSIVASSYRNNPFHSF 271
Query: 474 RHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAIL 533
HA+ V QT+F +L + +S +E L +++A +CHDLDH +N FQ +S +A+L
Sbjct: 272 NHAIAVTQTIFLILLKTNLFNILSPIEKLSIIIASICHDLDHPALSNRFQINMKSSIAVL 331
Query: 534 YST-STMEHHHFDQCVMILNSE-SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKS 591
Y+ S +E+HH C+ IL S+ N + L+ + K V+ IL+TD+ +F K
Sbjct: 332 YNNKSVLENHHLSICLGILESKIGNELLSTLTVEEKKQFFRRVKILILATDMENHFTYKK 391
Query: 592 KFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE 651
+F +++ F W E ++LL M + + D+S + +++ ++ A + +EFF+Q DLE
Sbjct: 392 QFDDIIST--FSWDNSEHRDLLLIMFLKSADISNELRSFDISNKWANALMEEFFNQSDLE 449
Query: 652 KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRW 711
K LN P+ +K L QV FI+ LP Y+ L + P + +N+ W
Sbjct: 450 K--LNNLPLTPFMEREKVVLHLTQVSFIEKFLLPSYQSLQNLLPSLEDFVQRIIENKEIW 507
Query: 712 QD 713
+
Sbjct: 508 SN 509
>UniRef50_O76083 Cluster: High affinity cGMP-specific 3',5'-cyclic
phosphodiesterase 9A; n=62; Eumetazoa|Rep: High affinity
cGMP-specific 3',5'-cyclic phosphodiesterase 9A - Homo
sapiens (Human)
Length = 593
Score = 157 bits (382), Expect = 9e-37
Identities = 93/286 (32%), Positives = 153/286 (53%), Gaps = 9/286 (3%)
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFM 496
M+ LV F I L RW+ V NYR +HN+RH VAQ M++M+ ++
Sbjct: 278 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 337
Query: 497 SDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSES 555
S +IL L+ A +CHDLDH G NN +Q + LA+ Y+ S +E+HH IL
Sbjct: 338 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPE 397
Query: 556 NNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCG 615
NIF + P +K + + T IL+TD+A + + F E ++N FD+ +E LL
Sbjct: 398 CNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKM 455
Query: 616 MMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIA-MMDREKKDELPQM 674
+++ CD+S +P EV + +E+F Q D EK + P+A MDR+K +
Sbjct: 456 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE--GLPVAPFMDRDKVTK-ATA 512
Query: 675 QVGFIDTICLPLYKVLSDTFPWMTPLRTGTA-DNRRRWQDLAEKVD 719
Q+GFI + +P+++ ++ FP + + ++R R+++L +++D
Sbjct: 513 QIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL-KRID 557
>UniRef50_Q4SVG0 Cluster: Chromosome 1 SCAF13759, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 1
SCAF13759, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 954
Score = 157 bits (381), Expect = 1e-36
Identities = 64/158 (40%), Positives = 105/158 (66%)
Query: 397 EDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCR 456
E+ ++ + +P++ ++ F F DF+ ++ D + ++M+ + ++V+KFHIP +VL R
Sbjct: 561 EELQEILAEVLPNSRKAEIFEFHFCDFEHSELDLVKCGIKMYYELKVVDKFHIPREVLVR 620
Query: 457 WILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
++ SV K YR + YHNWRH NV QTMF +L TG ++R+ +DLE + ++ A CHD+DHR
Sbjct: 621 FMYSVSKGYRRITYHNWRHGFNVGQTMFTLLMTGDLKRYYTDLECMAMVTAGFCHDIDHR 680
Query: 517 GTNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSE 554
GTNN +Q K+ +PLA L+ +S +E HH + +L E
Sbjct: 681 GTNNLYQMKSGNPLAKLHGSSILERHHLEFGKTLLRDE 718
Score = 48.0 bits (109), Expect = 0.001
Identities = 49/173 (28%), Positives = 72/173 (41%), Gaps = 29/173 (16%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLDHNYEPRPGQIT 115
F+ +D T Y+T +L +PI N + D+V V NK DG T D RPG+
Sbjct: 155 FSGFVDELTEYQTRSVLAVPIMNGK-DMVAVLMATNKLDGPSFTAK--DEEVRRRPGRAE 211
Query: 116 RGPVASHWYSLYYFGNQRLYTYLRRKLSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLF 175
G LR FSS + +YL F + ++ L
Sbjct: 212 SGSSC----------------VLR-------PPSFSS---QTLNKYLNFANLLLRVFHLS 245
Query: 176 ESSVLEYKRNQILLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILD 228
E +R Q+LL A +FEE +++E K + R L C+R +V +LD
Sbjct: 246 YLHNCETRRGQVLLWSASKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLD 298
Score = 47.6 bits (108), Expect = 0.001
Identities = 23/39 (58%), Positives = 28/39 (71%), Gaps = 2/39 (5%)
Query: 655 LNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDT 693
L+ QP MMDR K DELP++Q GFID +C +YKV DT
Sbjct: 870 LSLQP--MMDRNKADELPKLQCGFIDFVCAFVYKVRRDT 906
Score = 44.8 bits (101), Expect = 0.010
Identities = 23/88 (26%), Positives = 44/88 (50%), Gaps = 5/88 (5%)
Query: 316 ENSAGVRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQM 370
E+ +R +L +PIVN ++++GVA N+ F E D ++ E+ F G + N
Sbjct: 419 ESGWTIRNVLSLPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLTQFLGWSMLNPDT 478
Query: 371 YENACKLMAKQKVALECLSYHATASAED 398
Y+ KL ++ + + + YH ++
Sbjct: 479 YDKMNKLENRKDIYQDMVMYHVKCRKDE 506
>UniRef50_A2DJF3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 1006
Score = 157 bits (381), Expect = 1e-36
Identities = 87/378 (23%), Positives = 176/378 (46%), Gaps = 8/378 (2%)
Query: 321 VRTLLCMPIVNANKDVIGVAQLINK--FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLM 378
++ ++ P++ + +IG Q+ D+ + F +F L I ++ + A
Sbjct: 609 LKKIIAFPLLTNDNAIIGTIQIGTNHIILPEDMKLLNCFCVFAALSIDKDRLRKVASVGA 668
Query: 379 AKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMF 438
++ ++ + D K E +T +F +D R +
Sbjct: 669 SEARIRKYLMDNERDVG--DIPKFLTIEPTKQDTLLKINFDAQRWDGIGH--LRVVFYLM 724
Query: 439 LQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSD 498
++++F + D ++ + +Y V YHNWRHA++V Q + L + + +
Sbjct: 725 NYFGVLKQFKVRNDTFLHFLDEISNSYNKVPYHNWRHAVDVTQFVSYQLVVSGVYKILKP 784
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNN 557
+E+ LL+A +CHD++H G N + K E+PL IL+ + S ME HH + +++++ N
Sbjct: 785 IELYALLIAAICHDVNHDGFTNVYNEKAETPLGILFKNQSVMETHHCQVAIQVVSNDKCN 844
Query: 558 IFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMM 617
IF + K + ++ IL TD+ + + +D G ++ + ++ ++
Sbjct: 845 IFSSFDSPLIKQIWSLIIALILKTDMGKHHSTLEAINKRLDEGPLKPDNEQDRFMMMELI 904
Query: 618 MTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVG 677
+ D+S +++P+E+ + ++ +EFF QGDLEK + + DR D+ P+ Q+G
Sbjct: 905 LKCSDISNVSRPFELADKWCDVLCEEFFRQGDLEKTSGMEYTSPLNDRAHLDK-PKSQIG 963
Query: 678 FIDTICLPLYKVLSDTFP 695
F +CLPL+ + P
Sbjct: 964 FYTFVCLPLFVTAARAMP 981
Score = 54.8 bits (126), Expect = 9e-06
Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA A S + +NI+D R + S + R+LL +PI + V GV ++IN+
Sbjct: 389 IAGYTASSGECVNITDAYSDSRFDKTSDIQTGFKTRSLLTVPIYDNRGAVAGVTEMINRK 448
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
F + D+ + AF +FCG+ I N +Y + +LM K +E
Sbjct: 449 DGKSFDDDDIKMMVAFNVFCGISIDNANLYNTSLQLMNNLKSFIE 493
Score = 41.9 bits (94), Expect = 0.070
Identities = 18/46 (39%), Positives = 29/46 (63%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
Y +F+ D +TG+KT +L +PI + G V GV ++IN+ DG+
Sbjct: 406 YSDSRFDKTSDIQTGFKTRSLLTVPIYDNRGAVAGVTEMINRKDGK 451
Score = 40.7 bits (91), Expect = 0.16
Identities = 23/112 (20%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
Query: 129 FGNQRLYTYLRRKLSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQIL 188
+ N+ + ++ K F D+++ + FCGI I NA L+ +S L+ N
Sbjct: 432 YDNRGAVAGVTEMINRKDGKSFDDDDIKMMVAFNVFCGISIDNANLYNTS-LQLMNNLKS 490
Query: 189 LALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILDTDHCESSHLERI 240
A + + + L ++ ++++ + ++ A ++ D D E + L+ I
Sbjct: 491 FIEASAAMGKDAQLNNVIHELISTMKGVINGSYAACYVYDNDTEEITLLDEI 542
Score = 36.7 bits (81), Expect = 2.6
Identities = 22/46 (47%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
Query: 183 KRNQILLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILD 228
+R Q LLA+A IF +L+ L+ IM A +LL ERC++FILD
Sbjct: 319 ERLQALLAVAEVIFGVL-DLDSLLPTIMDTACNLLNTERCSLFILD 363
>UniRef50_A2FQB0 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1042
Score = 151 bits (366), Expect = 8e-35
Identities = 96/393 (24%), Positives = 182/393 (46%), Gaps = 21/393 (5%)
Query: 324 LLCMPIVNANKDVIGVAQLINK----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMA 379
+L +P+++ DV+GV +++NK F++ DV + +AF F + I N++ + A +
Sbjct: 661 ILAVPLISTEGDVMGVVEMVNKINGKFSDADVMLLQAFCSFAAITIENSRNKQLAPMSVR 720
Query: 380 KQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFL 439
+ + + + K+ + + + + F FD DE+ R +
Sbjct: 721 SARPVI--------FNDRNVEKMA---MTTEQMEGMTGISFCAFDFGDEELVRMVFSNLV 769
Query: 440 QCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDL 499
+ E ++ L +IL V+ Y V YHNWRHA +V Q + +L++ + +
Sbjct: 770 IFGVPENMRTNHETLLHFILQVRLLYNDVPYHNWRHACDVVQFVSFVLQSINAKEIFEPI 829
Query: 500 EILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTSTMEH-HHFDQCVMILNSESNNI 558
EI + +A +CHD H G +N F + +PL +YS E H ++NS NI
Sbjct: 830 EISAIFIAAICHDAGHDGYSNIFNRQASTPLGQIYSGKNCEELFHLSLIARVVNSPECNI 889
Query: 559 FQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMM 618
F ++ ++ I+ TDL ++ S+ + D + Q + + +++
Sbjct: 890 FSNMTHATMAKFWAMMIRMIIDTDLEVF----SQVMSNNSLNNLDMKNQNSRIKVLSLIL 945
Query: 619 TACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGF 678
++S +A+P++V R ++ E++ QGD+EK L + + + + P+ Q F
Sbjct: 946 ILSNISNVARPFDVAMRWLDCLSTEYYKQGDIEK-SLGMKYTNVANNRALPDKPKEQSNF 1004
Query: 679 IDTICLPLYKVLSDTFPWMTPLRTGTADNRRRW 711
I+T LPL KV++ FP + + A N W
Sbjct: 1005 INTYALPLSKVVATLFPALDVICKSIATNLVEW 1037
Score = 49.2 bits (112), Expect = 5e-04
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 7/120 (5%)
Query: 296 KSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK-----FTEGD 350
K LNI D N + +T+L +PI N +IGV ++INK F+ D
Sbjct: 465 KPLNIHDAYSDPDFNVATDIATGYKTKTILSVPIFNNRGKIIGVTEMINKKNGQAFSMWD 524
Query: 351 VSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSA 410
++ + F +FCG+ + N ++Y + M+K+ + +S+ + ED ++ D + +A
Sbjct: 525 TNLIQIFNVFCGISLENARLYNESID-MSKKLKSFFGISF-SVNKTEDIKRILSDIMKNA 582
Score = 48.4 bits (110), Expect = 8e-04
Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 8/74 (10%)
Query: 31 TSGMHTPI-PGKIPHKLTAIKYITIQ-------FNSEIDARTGYKTELILCMPICNYEGD 82
T+G+ PI G + +T K + I FN D TGYKT+ IL +PI N G
Sbjct: 445 TNGIEIPINKGIVGKTVTQAKPLNIHDAYSDPDFNVATDIATGYKTKTILSVPIFNNRGK 504
Query: 83 VVGVAQIINKTDGE 96
++GV ++INK +G+
Sbjct: 505 IIGVTEMINKKNGQ 518
Score = 47.6 bits (108), Expect = 0.001
Identities = 24/104 (23%), Positives = 56/104 (53%), Gaps = 1/104 (0%)
Query: 125 SLYYFGNQRLYTYLRRKLSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKR 184
S+ F N+ + ++ + FS D + + + FCGI ++NA+L+ S+ K+
Sbjct: 495 SVPIFNNRGKIIGVTEMINKKNGQAFSMWDTNLIQIFNVFCGISLENARLYNESIDMSKK 554
Query: 185 NQILLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILD 228
+ ++ S+ + +++ +++ IM AR L+ +R ++F++D
Sbjct: 555 LKSFFGISFSV-NKTEDIKRILSDIMKNARRGLQAKRASIFVVD 597
Score = 44.8 bits (101), Expect = 0.010
Identities = 17/42 (40%), Positives = 32/42 (76%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
++N ++D TG++T IL +P+ + EGDV+GV +++NK +G+
Sbjct: 645 RWNPKVDEVTGFQTTNILAVPLISTEGDVMGVVEMVNKINGK 686
>UniRef50_A2E5S0 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1275
Score = 147 bits (356), Expect = 1e-33
Identities = 120/441 (27%), Positives = 204/441 (46%), Gaps = 34/441 (7%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAG-ENSAGVRT--LLCMPIVNANKDVIGVAQLI 343
IA VA +SLNI D +D G +N G RT +L +PI N + + IGV +LI
Sbjct: 852 IAGYVAEKGESLNIPDA---YKDPRFHRGVDNDTGYRTRSILAVPIKNNSNETIGVVELI 908
Query: 344 NK--------FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATAS 395
NK FT+ D + FA F G+ Q +N +A+ +
Sbjct: 909 NKDIIKNGGVFTKEDEKLTSGFATFAGVAFD--QHSDN--NRSGSHTLAIMLSNMMNAEE 964
Query: 396 AEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLC 455
A S Q + + +F+F +++ D+ R + +F + L ++F I L
Sbjct: 965 ANSFSPPKQIALNEEQMTRFDTFRFDVATVSEIDSARFIMTIFYKLGLSQRFKINNSRLI 1024
Query: 456 RWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDH 515
R+IL+V Y ++NW+ A+ AQ ++ +L T ++ ++DLE L L+V+ +CHD+D+
Sbjct: 1025 RFILAVHDGYMKSPFYNWQRAVASAQFVYYILTTTDLKNILTDLEKLALIVSTICHDIDY 1084
Query: 516 RGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVV 574
+++ Q+ TE LA+LY + ME HH + + IL NI + L+ D + ++
Sbjct: 1085 TSVDDSNQS-TEIALAVLYHNRPVMEMHHCEHTISILERSEENILETLNADDSQSCWKMI 1143
Query: 575 ETAILSTDLAMYFKKKSKFLELV-DNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQ 633
+ IL T++A +F + L+ N + + +E + L+ ++ A D S + + V
Sbjct: 1144 ISLILGTNMAKHFNTVTTLQSLIFPNKMINMKLEEHRLLIMQFIIKASDASYACRNFPVC 1203
Query: 634 HRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDT 693
R F D+ + KL + L QVGFI P++ +L+
Sbjct: 1204 QREGTKAYKMFTDKTAIGKL-------------FQRYLVNSQVGFIILYAEPMFTLLTHV 1250
Query: 694 FPWMTPLRTGTADNRRRWQDL 714
FP + PL N + W+ L
Sbjct: 1251 FPSVDPLLEQVKLNLQYWKQL 1271
Score = 53.2 bits (122), Expect = 3e-05
Identities = 29/94 (30%), Positives = 51/94 (54%), Gaps = 1/94 (1%)
Query: 142 LSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSN 201
++ + FS DVE+ + F GI + N+ + +S+ +R Q +L S+
Sbjct: 741 MNKQNGEAFSDADVELTKAMCVFTGIALANSIVIDSAFASSQRVQAMLKTV-SMLTHGEA 799
Query: 202 LECLVTKIMTEARDLLKCERCAVFILDTDHCESS 235
L L+ IM+ +RDL+ +RC++FILDT+ + S
Sbjct: 800 LSGLLHHIMSTSRDLIDADRCSLFILDTNSSKLS 833
Score = 48.8 bits (111), Expect = 6e-04
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 9/106 (8%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLINK--- 345
VAR+ +++NI D + R N SA + G RT ++ +P+ + +IGV QL+NK
Sbjct: 689 VARTGETINIPDCYEDSRFN--SAIDKKTGYRTKSMMTIPVHDQRHSIIGVVQLMNKQNG 746
Query: 346 --FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLS 389
F++ DV + +A +F G+ + N+ + ++A + + L+ +S
Sbjct: 747 EAFSDADVELTKAMCVFTGIALANSIVIDSAFASSQRVQAMLKTVS 792
Score = 47.6 bits (108), Expect = 0.001
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLD 104
Y +FNS ID +TGY+T+ ++ +P+ + ++GV Q++NK +GE +++ ++
Sbjct: 702 YEDSRFNSAIDKKTGYRTKSMMTIPVHDQRHSIIGVVQLMNKQNGEAFSDADVE 755
Score = 39.5 bits (88), Expect = 0.37
Identities = 16/38 (42%), Positives = 25/38 (65%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
+F+ +D TGY+T IL +PI N + +GV ++INK
Sbjct: 873 RFHRGVDNDTGYRTRSILAVPIKNNSNETIGVVELINK 910
>UniRef50_UPI00006CBCA5 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 649
Score = 144 bits (350), Expect = 7e-33
Identities = 87/304 (28%), Positives = 148/304 (48%), Gaps = 6/304 (1%)
Query: 429 DTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLK 488
+T L +F ++ I D+L + ++K Y YHN HA +V QT LK
Sbjct: 341 ETSFLLLYLFQSNNILASVDIEPDILFNFFKQIEKGYNDNLYHNRLHAFDVLQTANFFLK 400
Query: 489 TGKMERF--MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFD 545
+ +++ ++ + ++ CHD DH G NNAF T +A+ Y+ S +E+HH
Sbjct: 401 SCNFIEIAAINEFDLCTIYISAACHDYDHPGVNNAFIINTSHEIALTYNDQSVLENHHAS 460
Query: 546 QCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQ 605
+ + N ++ +I + Y+ +V + ILSTD+A +F +K + ++D +
Sbjct: 461 KTFQLFNDQNLDITANFTKEQYRSFREMVISIILSTDMAKHFSDIAKLKSRLGTDDYDIK 520
Query: 606 AQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDR 665
++ K++ ++ ACDVS K W V + A V EF+ QGD E+ Q Q + DR
Sbjct: 521 GKD-KQMCIDTIIHACDVSNPVKTWNVYQQWAHRVLSEFWSQGDQERSQ-GIQITYLCDR 578
Query: 666 EKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKVDMGLTWI 725
+ + QVGFID I PLY+V+ + P + N+++W +L D L +
Sbjct: 579 YTTN-TAKSQVGFIDFIVKPLYEVICNFLPELKNYMQQIDSNKQKWNELVSFYDQDLDCL 637
Query: 726 DHDT 729
+T
Sbjct: 638 QCNT 641
>UniRef50_UPI00015B4893 Cluster: PREDICTED: similar to camp-specific
3,5-cyclic phosphodiesterase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to camp-specific
3,5-cyclic phosphodiesterase - Nasonia vitripennis
Length = 1229
Score = 136 bits (329), Expect = 2e-30
Identities = 79/245 (32%), Positives = 128/245 (52%), Gaps = 8/245 (3%)
Query: 448 HIPYDVLCRWILS--VKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGL 504
H DV+ W L +++ Y YHN HA +V Q M L+ ++ R +S LEI+
Sbjct: 266 HFNLDVVRVWKLFTLIEEGYHSTNPYHNSIHAADVTQAMHCFLQEEQIRRHLSYLEIMAS 325
Query: 505 LVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALS 563
L+A + HDLDH G N F T + LA LY +TS +E+HH+ V L + + + L
Sbjct: 326 LIAAVTHDLDHPGVNQPFLVATSNHLAALYENTSVLENHHWRSAVGCL--LESGVSEQLP 383
Query: 564 PRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDV 623
R ++ + + IL+TD+ + ++F +D E D + E + + + + D+
Sbjct: 384 DRVKPELQRHISSLILATDITRQQEFLTRFKRYLDERELDMEQPEHRHFILQIALKCADI 443
Query: 624 SAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTIC 683
S +PW++ + + V +EFF QGD E+ QLN A+ DR +P++Q GF +
Sbjct: 444 SNPCRPWDISRKWSYKVCEEFFRQGDYER-QLNLPVTALCDRH-TTSIPKIQAGFFKFVV 501
Query: 684 LPLYK 688
LPLY+
Sbjct: 502 LPLYE 506
>UniRef50_UPI0000DB7125 Cluster: PREDICTED: similar to
Phosphodiesterase 1c CG14940-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Phosphodiesterase
1c CG14940-PA - Apis mellifera
Length = 731
Score = 135 bits (327), Expect = 4e-30
Identities = 87/264 (32%), Positives = 141/264 (53%), Gaps = 14/264 (5%)
Query: 443 LVEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTM-FAMLKTGKMERFMSDL 499
++ KF +P VL ++ V++ Y + YHN HA +VAQTM + + +TG M +++DL
Sbjct: 411 MIHKFKVPATVLECFLGRVEEGYCRHRNPYHNNLHAADVAQTMHYILCQTGLMN-WLTDL 469
Query: 500 EILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNI 558
EI LVA + HD +H GT N F + S A+LY+ + +E+HH I+ + NI
Sbjct: 470 EIFATLVAAIIHDYEHTGTTNNFHVMSGSDTALLYNDRAVLENHHISASFRIMREDECNI 529
Query: 559 FQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMM 618
Q LS ++++ +V +L+TD++ +F++ ++ E K +++
Sbjct: 530 LQNLSREEFREFRSLVIDMVLATDMSFHFQQLKNMKNILSLAE----PSVDKSKAVSLVL 585
Query: 619 TACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEK-LQLNQQPIAMMDREKKDELPQMQVG 677
CD+S AK W++ HR + +EFF QGD EK L L P+ DR + + Q+G
Sbjct: 586 HCCDISHPAKRWDLHHRWTMQLLEEFFRQGDKEKALGLPFSPLC--DR-NNTLVAESQIG 642
Query: 678 FIDTICLPLYKVLSDTFPW-MTPL 700
FI+ I P +V SD +TPL
Sbjct: 643 FIEFIVEPSMQVCSDMLETVLTPL 666
>UniRef50_A7SGA1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 358
Score = 135 bits (327), Expect = 4e-30
Identities = 79/254 (31%), Positives = 135/254 (53%), Gaps = 10/254 (3%)
Query: 442 ELVEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTMFAMLKTGKMERFMSDL 499
+++ F I L R++ V+ Y+ YHN HA +V T+ L+ + +++SDL
Sbjct: 109 DMLRNFKIHAMTLDRFLQDVETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDL 168
Query: 500 EILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNI 558
E+ GLL++ + HDL+H GT NAF + S LA+LY+ S +E+HH IL + NI
Sbjct: 169 EVFGLLLSAIIHDLEHTGTTNAFHINSRSDLALLYNDRSVLENHHVSCAFRILQDDEKNI 228
Query: 559 FQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMM 618
L+ Y DV ++ +L+TD++ +F++ L L+ E +E++ +++
Sbjct: 229 LSGLNLEQYADVRSLMIDTVLATDMSSHFEQ----LRLMKVALVAGSPIENREVV-QLLL 283
Query: 619 TACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGF 678
D+S K W + + + +EFF QGD+E ++L + DR +P+ Q+GF
Sbjct: 284 HVADISNPTKDWTIHRQWTTKIMEEFFTQGDME-IELGLDVSPLCDR-STTLIPESQIGF 341
Query: 679 IDTICLPLYKVLSD 692
ID I P +V S+
Sbjct: 342 IDFIVSPALEVCSE 355
>UniRef50_A4RV03 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 401
Score = 134 bits (325), Expect = 7e-30
Identities = 85/272 (31%), Positives = 138/272 (50%), Gaps = 13/272 (4%)
Query: 456 RWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDH 515
R++ V+ YR YH ++HA++V T + + K + M+ +EI LLVA L HDLDH
Sbjct: 56 RFLSEVEGMYRDNPYHCFKHAVDVTHTTYLYICAVKEQVSMTQVEIFSLLVAALVHDLDH 115
Query: 516 RGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMIL-NSESNNIFQALSPRDYKDVMHV 573
G N + T +A+ Y+ S +E+ H + + N+E NI A YK++
Sbjct: 116 PGVTNGYLIATHDNIALTYNDESVLENLHLSRFFSLCQNNEDANILSAFDESTYKEIRRS 175
Query: 574 VETAILSTDLAMYFKKKSKFLELVDNGE---------FDWQAQEKKELLCGMMMTACDVS 624
+ + +L TD+A +FK S+ ELV G+ ++++L+ +++ D+S
Sbjct: 176 IISCVLHTDMAHHFKLVSRLNELVALGKKNNIINGSPMKSTTDDERQLMLNVLLHCADIS 235
Query: 625 AIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICL 684
KP E+ + A V +EFF+QGD E+ + MMDRE + Q+ FI+ +
Sbjct: 236 NAVKPNELCVKWASRVLEEFFNQGDRERSR-GMSISPMMDRE-TTSVGLSQINFIEFVIA 293
Query: 685 PLYKVLSDTFPWMTPLRTGTADNRRRWQDLAE 716
PLY FP + L T +NRR +Q+ E
Sbjct: 294 PLYVQFVAVFPALNGLLTRLIENRRYYQETYE 325
>UniRef50_Q14123 Cluster: Calcium/calmodulin-dependent 3',5'-cyclic
nucleotide phosphodiesterase 1C; n=128;
Euteleostomi|Rep: Calcium/calmodulin-dependent
3',5'-cyclic nucleotide phosphodiesterase 1C - Homo
sapiens (Human)
Length = 709
Score = 134 bits (324), Expect = 9e-30
Identities = 90/257 (35%), Positives = 141/257 (54%), Gaps = 15/257 (5%)
Query: 442 ELVEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTMFAML-KTGKMERFMSD 498
+L+ +F IP L ++ +++ Y K YHN HA +V QT+ +L KTG + ++++
Sbjct: 197 DLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTG-VANWLTE 255
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMIL-NSESN 556
LEI ++ + HD +H GT N F +T S AILY+ S +E+HH +L + E
Sbjct: 256 LEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEM 315
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGM 616
NI LS D+++ +V +++TD++ +F++ + E A EK + L M
Sbjct: 316 NILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE----AIEKPKALSLM 371
Query: 617 MMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELPQMQ 675
+ TA D+S AK W++ HR + +EFF QGD E +L L P+ DR K + Q Q
Sbjct: 372 LHTA-DISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLC--DR-KSTMVAQSQ 427
Query: 676 VGFIDTICLPLYKVLSD 692
VGFID I P + VL+D
Sbjct: 428 VGFIDFIVEPTFTVLTD 444
>UniRef50_Q005X2 Cluster: Phosphodiesterase 1; n=1;
Strongylocentrotus purpuratus|Rep: Phosphodiesterase 1 -
Strongylocentrotus purpuratus (Purple sea urchin)
Length = 680
Score = 133 bits (322), Expect = 2e-29
Identities = 76/254 (29%), Positives = 134/254 (52%), Gaps = 10/254 (3%)
Query: 442 ELVEKFHIPYDVLCRWILSVKKNYRPV--KYHNWRHALNVAQTMFAMLKTGKMERFMSDL 499
+L KF IP+ VL ++ +++ Y YHN HA +V QT+ ML + ++SDL
Sbjct: 255 DLQTKFKIPHSVLGAFLDAMELGYSKYGNPYHNLLHAADVTQTVHHMLARMGLVHWLSDL 314
Query: 500 EILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNI 558
EI L+A + HD +H GT NAF T+S +A+ Y+ + +E+HH ++ + NI
Sbjct: 315 EIFASLLAAIIHDFEHTGTTNAFHVNTKSDMAMFYNDRAVLENHHISSSFRLMRDDERNI 374
Query: 559 FQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMM 618
LS +Y ++ ++V +L+TD++ +F++ + ++ E A +K +++ + +
Sbjct: 375 LANLSKEEYTELRNLVIDMVLATDMSFHFQQIKQMKSMISTTE----ALDKPKVM-ALTL 429
Query: 619 TACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGF 678
D+S +K W+ ++ L+ EFF QGD E+ PI+ + L + Q+GF
Sbjct: 430 HCADISHPSKEWKFHYKWTTLLIREFFRQGDREREM--GLPISPLCDRNSTLLAESQIGF 487
Query: 679 IDTICLPLYKVLSD 692
ID I P + D
Sbjct: 488 IDFIVDPSMNICGD 501
>UniRef50_UPI000150A113 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 569
Score = 132 bits (320), Expect = 3e-29
Identities = 101/363 (27%), Positives = 173/363 (47%), Gaps = 16/363 (4%)
Query: 408 PSAETY--NLYSFQFHDFDLTDEDTCRATL----RMFLQCELVEKFHIPYDVLCRWILSV 461
P E Y NL S +F F+ E+ + +F Q + + + + +VL + +
Sbjct: 197 PQVENYFENLDSREFMVFEFFKENLGKELSILLNYLFEQYQCFQAWKLQPEVLYHFSDII 256
Query: 462 KKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERF--MSDLEILGLLVACLCHDLDHRGTN 519
++ Y YHN HA +V QTM LK + ++ ++I + VA HD++H G N
Sbjct: 257 QQKYLGNPYHNKIHAFDVTQTMHFFLKKCNFVQIGKLNKIDIGTVFVAAAIHDVEHPGFN 316
Query: 520 NAFQTKTESPLAILYS-TSTMEHHHFDQCVMIL-NSESNNIFQALSPRDYKDVMHVVETA 577
N FQ ++ LAILY+ S +E+HH +L ++ S NIF+ + + YK+V +
Sbjct: 317 NPFQMNAKTDLAILYNDKSPLENHHLSVTFKLLRDNPSINIFEGIDKKTYKNVRETLIQM 376
Query: 578 ILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIA 637
IL TD+ +F ++ + + EFD +A + K L ++ A DVS KP+ +
Sbjct: 377 ILKTDMNQHFTSLAQLKGRLASNEFDAKAAD-KPLCLNTLLHAADVSNPFKPFHIYQEWT 435
Query: 638 KLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWM 697
V +EF+ QGD+E+ + PI+ + + + Q+GFID I P ++ + P +
Sbjct: 436 HRVLNEFWIQGDVERSR--GLPISYLCDRYTTNIAKSQIGFIDFIVQPYFETICQFIPEL 493
Query: 698 TPLRTGTADNRRRWQDLAEKVDMGLTWIDHDTIDKPVEEFTALNEPLADVELTVTTLNCA 757
N++ WQ E D L + K +EE T E +LT++ ++
Sbjct: 494 LNYMPLFEQNKQEWQTYEEYYDRQLATLQAQ--QKKLEERTKTIED-KKKDLTISQIDKF 550
Query: 758 AGP 760
+ P
Sbjct: 551 STP 553
>UniRef50_Q4KL87 Cluster: MGC116558 protein; n=2; Xenopus|Rep:
MGC116558 protein - Xenopus laevis (African clawed frog)
Length = 342
Score = 132 bits (319), Expect = 4e-29
Identities = 79/267 (29%), Positives = 143/267 (53%), Gaps = 8/267 (2%)
Query: 436 RMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERF 495
+MF + +LV +F + + + ++ SV+K+Y+ +HN+ H +V Q M+ ++ +++
Sbjct: 56 QMFYELDLVTEFKMEPETVRCFLTSVQKHYQENPFHNFYHGFSVTQMMYCVISQCQLQEH 115
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSE 554
+S ++IL L+VA LCHDLDH G +N++Q ++ LA Y + S +E+HH+ IL+ +
Sbjct: 116 LSHIDILTLMVAALCHDLDHPGLSNSYQVNAQTDLARQYHNKSPLENHHWAVAWRILSQK 175
Query: 555 SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGE-FDWQAQEKKELL 613
+N+ P+ + + IL+TD+A + + L+ + N E F++ +E L
Sbjct: 176 QSNLLLGADPKQVPHIQQEIMELILATDMAHH----GEILQTLQNIENFNFSNREHVTAL 231
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQ 673
++ CD+S A+P E A + +E+F Q D EK + MDR+K +
Sbjct: 232 KKGLIKICDISNEARPAEQAEIWADALMEEYFLQSDREKDE-GLPVTPYMDRDKVKK-AD 289
Query: 674 MQVGFIDTICLPLYKVLSDTFPWMTPL 700
Q FI + +PL + L FP + L
Sbjct: 290 AQSSFISFLLIPLCEALCKHFPLLNNL 316
>UniRef50_P27815 Cluster: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A; n=160; Eumetazoa|Rep:
cAMP-specific 3',5'-cyclic phosphodiesterase 4A - Homo
sapiens (Human)
Length = 886
Score = 132 bits (319), Expect = 4e-29
Identities = 92/323 (28%), Positives = 159/323 (49%), Gaps = 13/323 (4%)
Query: 398 DTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRW 457
D +L E+ + + L F D+ TC + +F + +L++KF IP D + +
Sbjct: 360 DQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYM-IFQERDLLKKFRIPVDTMVTY 418
Query: 458 ILSVKKNYRP-VKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
+L+++ +Y V YHN HA +V Q+ +L T ++ +DLEIL L A HD+DH
Sbjct: 419 MLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHP 478
Query: 517 GTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVE 575
G +N F T S LA++Y+ S +E+HH +L ++ +IFQ LS R + + +V
Sbjct: 479 GVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVI 538
Query: 576 TAILSTDLAMYFKKKSKFLELVDNGEFDWQA-------QEKKELLCGMMMTACDVSAIAK 628
+L+TD++ + + +V+ + ++ ++L M+ A D+S K
Sbjct: 539 DMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCA-DLSNPTK 597
Query: 629 PWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYK 688
P E+ + + EFF QGD E+ + + M D+ + + QVGFID I PL++
Sbjct: 598 PLELYRQWTDRIMAEFFQQGDRER-ERGMEISPMCDKHTA-SVEKSQVGFIDYIVHPLWE 655
Query: 689 VLSDTFPWMTPLRTGTADNRRRW 711
+D T ++ R W
Sbjct: 656 TWADLVHPDAQEILDTLEDNRDW 678
>UniRef50_O18696 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-1; n=2; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-1 - Caenorhabditis elegans
Length = 664
Score = 132 bits (319), Expect = 4e-29
Identities = 79/260 (30%), Positives = 135/260 (51%), Gaps = 12/260 (4%)
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTMFAMLKTGKMER 494
+F + +++F +P L ++ +++ Y YHN HA +V Q+ ML +
Sbjct: 297 LFNRYGFMDRFKVPLTALENYLSALEVGYSKHNNPYHNVVHAADVTQSSHFMLSQTGLAN 356
Query: 495 FMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNS 553
+ DLE+L +L L HD +H G N F +++S A+LY+ S +E+HH C ++
Sbjct: 357 SLGDLELLAVLFGALIHDYEHTGHTNNFHIQSQSQFAMLYNDRSVLENHHVSSCFRLMKE 416
Query: 554 ESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELL 613
+ NI L+ +YK++ ++V +L+TD++ +F + ++ E +K + L
Sbjct: 417 DDKNILTHLTRDEYKELRNMVIEIVLATDMSTHFMQIKTMKSMLSLPE----GIDKNKAL 472
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELP 672
C +++ ACD+S AKPW + R + V +EFF QGDLE + L P+ DR +
Sbjct: 473 C-LIVHACDISHPAKPWNLHERWTEGVLEEFFRQGDLEASMGLPYSPLC--DRHTV-HVA 528
Query: 673 QMQVGFIDTICLPLYKVLSD 692
Q+GFID I P V +
Sbjct: 529 DSQIGFIDFIVEPTMVVCGE 548
>UniRef50_Q23AZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Tetrahymena thermophila SB210
Length = 577
Score = 132 bits (318), Expect = 5e-29
Identities = 82/306 (26%), Positives = 152/306 (49%), Gaps = 9/306 (2%)
Query: 428 EDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAML 487
+++ + + +F + L++ I + ++ YR YH+ H+ +V QT+ +
Sbjct: 268 QESSQLLVYLFDKYNLLDDLKIDSQKFINLSVRIQNGYRDNPYHDRLHSFDVTQTIHFFI 327
Query: 488 ---KTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHH 543
K G++ + S +E + + HD DH G NN F T++ LA+ ++ S +E+HH
Sbjct: 328 SRCKFGELAKLKS-MERAAMYFSAAIHDFDHPGYNNVFLINTQNILALKFNDQSVLENHH 386
Query: 544 FDQCV-MILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEF 602
MIL + + NIF S +YK +V +L+TD+ +F SK + +F
Sbjct: 387 VSSVYEMILKNHNLNIFSNFSNDEYKQFREMVVNMVLATDMTKHFADISKLKSRIAATDF 446
Query: 603 DWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAM 662
+ ++KK ++ ++ A D+S A+PWE+ ++ V EF+ QGD EK +L +
Sbjct: 447 EIDGKDKKTVM-ESLLHASDISNPARPWEICYQWTNKVMTEFWAQGDEEK-RLGLPVTYL 504
Query: 663 MDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKVDMGL 722
DR + + + Q GFID + PL++++S+ P + N+ +W +L K + L
Sbjct: 505 CDRVETN-TSKSQQGFIDFVVKPLFEIISNFLPELQQFMINFEQNKEKWAELLPKYEAEL 563
Query: 723 TWIDHD 728
+ D
Sbjct: 564 KALKED 569
>UniRef50_Q8SXR0 Cluster: RE69157p; n=9; Coelomata|Rep: RE69157p -
Drosophila melanogaster (Fruit fly)
Length = 834
Score = 130 bits (315), Expect = 1e-28
Identities = 83/253 (32%), Positives = 135/253 (53%), Gaps = 11/253 (4%)
Query: 444 VEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTM-FAMLKTGKMERFMSDLE 500
+ KF I +L ++ V++ Y + YHN HA++V QT+ + + TG M +++DLE
Sbjct: 440 IHKFKIAPGILEAFLHRVEEGYCRYRNPYHNNLHAVDVMQTIHYCLCNTGLMN-WLTDLE 498
Query: 501 ILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIF 559
I L+A L HD +H GT N F + S A+LY+ + +E+HH +L + NI
Sbjct: 499 IFASLLAALLHDYEHTGTTNNFHVMSGSETALLYNDRAVLENHHASASFRLLREDEYNIL 558
Query: 560 QALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMT 619
LS +++++ +V +L TD+ +F++ +L+ E A K+ + +++
Sbjct: 559 SHLSREEFRELRGLVIEMVLGTDMTNHFQQMKAMRQLLTLQE----ATIDKQKVLSLVLH 614
Query: 620 ACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFI 679
CD+S AK W V HR L+ +EFF QGDLEK +L + DR + + Q+ FI
Sbjct: 615 CCDISHPAKQWGVHHRWTMLLLEEFFRQGDLEK-ELGLPFSPLCDR-NNTLVAESQICFI 672
Query: 680 DTICLPLYKVLSD 692
D I P V+SD
Sbjct: 673 DFIVEPSMGVMSD 685
>UniRef50_O96075 Cluster: EFPDE1; n=1; Ephydatia fluviatilis|Rep:
EFPDE1 - Ephydatia fluviatilis
Length = 628
Score = 130 bits (313), Expect = 2e-28
Identities = 71/259 (27%), Positives = 139/259 (53%), Gaps = 5/259 (1%)
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYR--PVKYHNWRHALNVAQTMFAMLKTGKMER 494
+F + +L +K+ I L ++ V+ Y+ YHN HA +V QT+ ++ + +E
Sbjct: 243 LFRKHDLTKKYKILPSCLDAFLAKVEAGYQLHGNPYHNSTHAADVLQTVHYLISSTGLEH 302
Query: 495 FMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNS 553
++S LE+L +L+A HDL+H GT N F ++ + A+LY+ + +E+ H ++ +L
Sbjct: 303 WISSLEVLAILLAATVHDLEHTGTTNTFHIQSYTDYALLYNDRAVLENFHLNRAFTLLKE 362
Query: 554 ESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELL 613
+ NI + L D++ V +V +L+TD++ + + +L+ + + Q ++ + +
Sbjct: 363 DELNILKNLKLEDFRLVRSLVVEMVLATDMSSHSDQLKHMRQLISSPDVIVQIEKGRSKV 422
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQ 673
+++ D+S K WE + + +EFF QGD +++QL + + +R +P+
Sbjct: 423 LCLLLHMADISHPGKEWETHQEFSSRLVEEFFRQGD-QEMQLGRTCSPLCNR-NTTSVPE 480
Query: 674 MQVGFIDTICLPLYKVLSD 692
Q+GFID I P + V D
Sbjct: 481 CQLGFIDYIVSPSFDVCGD 499
>UniRef50_Q23RI8 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Tetrahymena thermophila SB210
Length = 807
Score = 128 bits (308), Expect = 8e-28
Identities = 90/318 (28%), Positives = 153/318 (48%), Gaps = 15/318 (4%)
Query: 418 FQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHAL 477
F +H + D + + +F + ++ K I L W + V Y+ YHN HA
Sbjct: 491 FTYHQ-KIQDNNLANLLIHLFNRYDVFFKAKIEPQHLFNWAVLVSNGYQDNFYHNKMHAF 549
Query: 478 NVAQTMFAMLKTGKMERF--MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS 535
+V QTM +++ +S LEI + +A HD H G NN + T + LAI Y+
Sbjct: 550 DVTQTMHYFMQSLNFIGIADLSGLEIGLMYIAAAAHDYQHPGFNNPYLINTRNELAIRYN 609
Query: 536 -TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFL 594
S +E+HH +++ E+ NIF L+ ++K + + IL TD + +F +K
Sbjct: 610 DKSPLENHHAFSTFLLMQEENCNIFVHLTKDEFKKSRERIISMILHTDNSQHFADLAKLK 669
Query: 595 ELVDNGEFDWQAQEKKELLCGM-MMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKL 653
+ + +FD ++K + +C M ++ + DVS KPWE+ + V DEF++QGDLE+
Sbjct: 670 GRLTSQDFD--PKDKDKDICMMSLLHSADVSNPYKPWEICRQWTFKVLDEFWNQGDLER- 726
Query: 654 QLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPW--MTPLRTGTADNRRRW 711
+ PI + + Q GFID I PLY+ + P ++P N+ +W
Sbjct: 727 -QSGLPITYLCDRFTTNTSKSQAGFIDFIVKPLYESVQKFLPLLDLSPFEV----NKAKW 781
Query: 712 QDLAEKVDMGLTWIDHDT 729
+L + + L I ++
Sbjct: 782 AELVDFYEQELQKIKRES 799
>UniRef50_A4HHP3 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania braziliensis
Length = 734
Score = 127 bits (306), Expect = 1e-27
Identities = 87/289 (30%), Positives = 142/289 (49%), Gaps = 7/289 (2%)
Query: 434 TLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQ-TMFAMLKTG-K 491
T + + +LV F++ VL R++++V+ Y P YHN H +V Q + M+ G
Sbjct: 425 TYLLLYKLDLVRYFNLDDAVLRRFLIAVQSAYHPNPYHNAMHGADVTQINYYIMIVAGLS 484
Query: 492 MERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMI 550
++ +S+ EI ++A HD DH G NN F ++T + LA LY+ S +E+HH +
Sbjct: 485 VKCCLSNEEIFAGIIAGAVHDFDHPGLNNNFHSRTGAYLATLYNDRSILENHHLACTFEL 544
Query: 551 LNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQA-QEK 609
L + NIF LS V + +L+TD+ + + F + +W + +E
Sbjct: 545 LRNPRYNIFATLSDEQRLLVRETILEMVLATDMGNHARIFKNFQVRMSEAT-EWHSKKED 603
Query: 610 KELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKK- 668
L M + D+S A+P + AK ++ EF+ QGD E+ +LN MDR K+
Sbjct: 604 VRLALSMSIKMADISNCARPNHIYAEWAKNISKEFYLQGDAER-KLNLSISPFMDRTKEM 662
Query: 669 DELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
E P+ QV F+ I P+ + +S P MT DN+ W+ E+
Sbjct: 663 GEFPKGQVSFMMYIVQPMVEAISALLPSMTFAVNLCVDNKEYWRRKTEE 711
>UniRef50_A2FK96 Cluster: GAF domain containing protein; n=3;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1174
Score = 126 bits (304), Expect = 3e-27
Identities = 99/432 (22%), Positives = 192/432 (44%), Gaps = 24/432 (5%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----- 345
VA S +N D Q R N M + ++L +PI+++ VIGV + ++K
Sbjct: 752 VATSGGEVNEEDPTQDRRFNTMFLSQMGIKPNSILAIPILDSLNQVIGVIEAVDKVGSPK 811
Query: 346 FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQD 405
FT D + + F+ F GL + M ++ + + L+ E +L
Sbjct: 812 FTADDQLLLKNFSAFAGLAMQRW-MAKSPEDFWKPESQLVTILTATELKMTEMPGRLNII 870
Query: 406 EIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY 465
E P T + S +F + R L F L+++F+I + + R+I S+ + Y
Sbjct: 871 E-PLLSTVS--SIEFDAVAFPKNEQFRILLFFFHDLGLLKEFNIQIETILRFITSISEQY 927
Query: 466 RPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTK 525
V +HN+ HA++V Q + ++K G++ + LEIL LLV+ +CHD+ HRG +K
Sbjct: 928 HHVPFHNFNHAVDVTQMAYMIVKVGRLFSNFTKLEILALLVSAICHDMGHRGKMGT-SSK 986
Query: 526 TESPLAILYSTS-TMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLA 584
++PL++L+ ME H + + S NI +L+ D +V ILST+ +
Sbjct: 987 VQTPLSLLFKDQPVMETFHCSSAIKTIGKPSCNILSSLNADQLHDFWVLVIDTILSTETS 1046
Query: 585 MYFK-KKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADE 643
+ K L + +++ + +++ ++++ A+P++ + +++DE
Sbjct: 1047 QHQKIIDDAKLSFAPDETLPLANTQQRARMMKLILRIGNLASCARPFDSTKSWSSVLSDE 1106
Query: 644 FFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTG 703
F D + + E+ + + I P +++LS P + +
Sbjct: 1107 FTDDSE------------NAGEKTPQEIARWNADHLKAIAAPAFELLSKAVPLLKGIGKQ 1154
Query: 704 TADNRRRWQDLA 715
N +W+++A
Sbjct: 1155 FKRNVEKWEEIA 1166
Score = 63.3 bits (147), Expect = 3e-08
Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA++ + +NI D R N + +++LC+PI N + ++G Q+INK
Sbjct: 584 IAGTVAKTGEIINIPDAYSDPRFNPAVDKKTGYLTKSILCVPIRNNDGSIMGCTQMINKL 643
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
FT+ D+ + AF +FCG+ + N Q+YE+A K L+
Sbjct: 644 DGNEFTKTDIELMSAFNVFCGIALSNAQLYESATITKKKMSAILD 688
Score = 58.8 bits (136), Expect = 6e-07
Identities = 27/82 (32%), Positives = 49/82 (59%), Gaps = 1/82 (1%)
Query: 149 EFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTK 208
EF+ D+E+ + FCGI + NAQL+ES+ + K+ +L + ++ S L LVT
Sbjct: 647 EFTKTDIELMSAFNVFCGIALSNAQLYESATITKKKMSAILDIVLNM-SSTSTLNQLVTN 705
Query: 209 IMTEARDLLKCERCAVFILDTD 230
+M+ A+DL++ + +F +D +
Sbjct: 706 LMSNAKDLVESKYVFIFAIDRE 727
Score = 56.0 bits (129), Expect = 4e-06
Identities = 23/54 (42%), Positives = 36/54 (66%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLD 104
Y +FN +D +TGY T+ ILC+PI N +G ++G Q+INK DG T++ ++
Sbjct: 601 YSDPRFNPAVDKKTGYLTKSILCVPIRNNDGSIMGCTQMINKLDGNEFTKTDIE 654
Score = 39.9 bits (89), Expect = 0.28
Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 8/67 (11%)
Query: 169 IQNAQLFESSV-------LEYKRNQILLALARSIFEEQSNLECLVTKIMTEARDLLKCER 221
+QNAQL ES++ +K LLA+A+ + E L+ K+MT+A+ + +R
Sbjct: 493 LQNAQLHESNIQNIQKARTNHKYYTALLAVAQELSAELDT-NALIRKVMTKAQSFINADR 551
Query: 222 CAVFILD 228
C++F++D
Sbjct: 552 CSLFLVD 558
>UniRef50_UPI0000D56333 Cluster: PREDICTED: similar to
cGMP-dependent 3,5-cyclic phosphodiesterase (Cyclic
GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE);
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
cGMP-dependent 3,5-cyclic phosphodiesterase (Cyclic
GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE) -
Tribolium castaneum
Length = 666
Score = 126 bits (303), Expect = 3e-27
Identities = 78/285 (27%), Positives = 136/285 (47%), Gaps = 12/285 (4%)
Query: 317 NSAGVRTLLCMPIVNANKDVIGVAQLINK----FTEGDVSIFEAFAIFCGLGIHNTQMYE 372
N ++ +LC P+ + +K +IG QL NK FT D I ++ G + + +
Sbjct: 318 NEFKLQNILCFPVRDEDK-IIGAVQLYNKRKGNFTRFDEEIANILSVHGGFALSQSLKFT 376
Query: 373 NACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETY-NLYSFQFHDFDLTDEDTC 431
+ + ++A + H + ++ K + P Y N F F + +T
Sbjct: 377 KSENFKIRNQLADNLMIRHEHVNMDEVMK--KIACPLIHQYPNFELFTFSPRSIVSLETT 434
Query: 432 RATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGK 491
+MF + F I +V ++ ++VK R V +HNW H + A + L +
Sbjct: 435 CLVFKMFERLGFFTTFGIKREVFAKFTMTVKNCCREVPFHNWMHLFSTAHFAYLCLTHLQ 494
Query: 492 M--ERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST--STMEHHHFDQC 547
+ +++++ LE L V CLCHD+D+R N++FQ L LYS+ S ME H Q
Sbjct: 495 LVEDKYITQLEALAYFVTCLCHDVDYRAANSSFQQTPSDGLCTLYSSPGSVMERHRLSQI 554
Query: 548 VMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSK 592
+ ILNSE N L+ +Y+ + +++ L+TDL+++FK +K
Sbjct: 555 LRILNSEGCNFVDILNRENYRLFLDLLKDLTLATDLSIHFKHYTK 599
Score = 35.5 bits (78), Expect = 6.1
Identities = 19/84 (22%), Positives = 37/84 (44%)
Query: 147 SKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLV 206
SK+ + ++ FC + N E + K+ + LL R + ++ L+
Sbjct: 175 SKKEDNFIAKLVNELFRFCLPVLFNTLATEEEARQRKQYETLLDATRKFYSHIDDIHELI 234
Query: 207 TKIMTEARDLLKCERCAVFILDTD 230
T I E R L+ +C++F+ + D
Sbjct: 235 TVITNETRQLINARKCSLFLANLD 258
>UniRef50_Q13946 Cluster: High affinity cAMP-specific 3',5'-cyclic
phosphodiesterase 7A; n=73; Euteleostomi|Rep: High
affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
- Homo sapiens (Human)
Length = 482
Score = 125 bits (302), Expect = 4e-27
Identities = 92/324 (28%), Positives = 157/324 (48%), Gaps = 14/324 (4%)
Query: 373 NACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSA----ETYNLYSFQFHDFD-LTD 427
N +L++ Q+ + TA + + L D A E ++F FD LT+
Sbjct: 107 NIRRLLSFQRYLRSSRFFRGTAVSNSLNILDDDYNGQAKCMLEKVGNWNFDIFLFDRLTN 166
Query: 428 EDTCRA-TLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFA 485
++ + T +F L+E FH+ L R+++ ++++Y YHN HA +V Q M
Sbjct: 167 GNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHC 226
Query: 486 MLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHF 544
LK K+ ++ +IL L+A HDLDH G N F KT LA LY +TS +E+HH+
Sbjct: 227 YLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHW 286
Query: 545 DQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDW 604
V +L + +F L + + + IL+TD++ + S F +D G+
Sbjct: 287 RSAVGLL--RESGLFSHLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCL 344
Query: 605 QAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMM 663
+ + L+ M + D+ + WE+ + ++ V +EFF QGD+E K L P+
Sbjct: 345 EDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLC-- 402
Query: 664 DREKKDELPQMQVGFIDTICLPLY 687
DR + + +Q+GF+ + PL+
Sbjct: 403 DRH-TESIANIQIGFMTYLVEPLF 425
>UniRef50_UPI0000D56A7E Cluster: PREDICTED: similar to High-affinity
cAMP-specific and IBMX-insensitive 3,5-cyclic
phosphodiesterase 8A; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to High-affinity cAMP-specific and
IBMX-insensitive 3,5-cyclic phosphodiesterase 8A -
Tribolium castaneum
Length = 862
Score = 124 bits (300), Expect = 8e-27
Identities = 89/308 (28%), Positives = 149/308 (48%), Gaps = 17/308 (5%)
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKME 493
+ +F ++ + VL W++ ++ NY YHN HA +V Q L+ K++
Sbjct: 542 MNLFNNFDVAAVLNCDEKVLYNWLIIIEANYHTDNTYHNSTHAADVMQATAGFLEREKLK 601
Query: 494 RFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTSTM--EHHHFDQCVMIL 551
M L+ L+A HD+DH G +NAF + +++PLAILY+ T+ HH + L
Sbjct: 602 SIMDPLDEATSLIAAAAHDVDHPGKSNAFLSNSDNPLAILYNDITILESHHAALMFKLTL 661
Query: 552 NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLEL---------VDNGEF 602
E N+F+ L YK H V IL+T++ +F+ +KF+ + ++ G+
Sbjct: 662 GDERVNVFKNLDRETYKIARHNVIDMILATEMTKHFEHLAKFVNVFCTKTSNSDIELGDQ 721
Query: 603 DWQAQEKKE---LLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQP 659
D+ + E L+ MM+ DVS +P + A+ +A+E+F Q D EK +
Sbjct: 722 DFPLLTQPENITLIKRMMIKCSDVSNPTRPLRLCVEWARRIAEEYFQQTDEEKERGLPVV 781
Query: 660 IAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKVD 719
+ M DR +P+ Q+GF+D I +++ + F M L T N RW++ E+
Sbjct: 782 MPMFDR-NTCSIPKSQIGFVDYIINDMFEAW-NAFIDMPDLITYMRQNYIRWKEFDEQGL 839
Query: 720 MGLTWIDH 727
L I H
Sbjct: 840 NTLADISH 847
>UniRef50_A5JZK2 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 1164
Score = 123 bits (297), Expect = 2e-26
Identities = 74/246 (30%), Positives = 134/246 (54%), Gaps = 5/246 (2%)
Query: 449 IPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVAC 508
IP + + ++ V+K Y V YHN HA V Q F + K + M L + ++
Sbjct: 850 IPMNSIINFLSFVEKQYNNVPYHNTIHATMVTQKFFCLSKKLGIYDHMEYKIKLVMFISG 909
Query: 509 LCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNIFQALSPRDY 567
+CHD+ H G NN F + PL+I+Y+ S +E++H IL N+ ++ S +D+
Sbjct: 910 ICHDVGHPGYNNLFFVNSLHPLSIIYNDISVLENYHASITFKILQLNQCNLLKSFSEKDF 969
Query: 568 KDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDW-QAQEKKELLCGMMMTACDVSAI 626
+ + + ILSTD+ +F+ SKF +N +FD+ + + +L M++ + D+S
Sbjct: 970 RLIRSYIIELILSTDMKYHFEIISKFRIRRENEDFDYVKNNDDLLVLIKMIIKSADISHG 1029
Query: 627 AKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIA-MMDREKKDELPQMQVGFIDTICLP 685
+ W ++ + V EF+ QGD E+L+ N+ P++ + DR K +E+ Q Q+ F+ + +P
Sbjct: 1030 SVKWNEHYKWCQRVLCEFYSQGD-EELK-NKMPLSPLCDRTKHNEVCQSQITFLKFVVMP 1087
Query: 686 LYKVLS 691
L++ L+
Sbjct: 1088 LFEELT 1093
>UniRef50_Q4D500 Cluster: Phosphodiesterase, putative; n=3;
Trypanosoma cruzi|Rep: Phosphodiesterase, putative -
Trypanosoma cruzi
Length = 708
Score = 122 bits (293), Expect = 5e-26
Identities = 75/264 (28%), Positives = 135/264 (51%), Gaps = 6/264 (2%)
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQ-TMFAMLKTGKMERF 495
+ ++ + KF+I + WI V+ Y YHN HA +V T + + K G +ER
Sbjct: 428 LLIKYSFLSKFNIDEQIALNWISCVEAGYNGNPYHNSMHAADVLHITHYILSKGGMIERC 487
Query: 496 -MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNS 553
+SDL++ L A HD +H G NN F KT++ AI+Y+ S +E+ H ++ +
Sbjct: 488 QLSDLQVFAALFAAAIHDYNHPGVNNNFHIKTQTYSAIVYNDRSVLENAHVSSVFELMKN 547
Query: 554 ESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELL 613
NI ++ S K++ V +L+TD++++ K + F + ++ + +E + L
Sbjct: 548 PRFNILESFSEDQQKEIRETVIEMVLATDMSLHGKHIAHFNDRLEE-HASFTERENQNLA 606
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQ 673
M + D+S +P E+ + + ++DEF+ QGD E+ L Q MDR + L +
Sbjct: 607 LVMALKMADISNCGRPLEIYLKWSSKLSDEFYLQGDRER-NLGVQCSPFMDR-MEPALAK 664
Query: 674 MQVGFIDTICLPLYKVLSDTFPWM 697
Q+ FI+ I +P ++ ++ P M
Sbjct: 665 GQILFINYIIIPFFEKMAVFLPKM 688
>UniRef50_UPI00015B5210 Cluster: PREDICTED: similar to
ENSANGP00000018818; n=2; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000018818 - Nasonia
vitripennis
Length = 849
Score = 121 bits (291), Expect = 9e-26
Identities = 78/278 (28%), Positives = 138/278 (49%), Gaps = 7/278 (2%)
Query: 443 LVEKFHIPYDVLCRWILSVKKNYRP-VKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEI 501
+ E+ L W+ ++ NY V YHN HA +V Q +++ ++++ + L+
Sbjct: 550 VAERLECDERTLQNWLTIIEANYNSHVSYHNSTHATDVLQACARFMRSDRIQQILDPLDE 609
Query: 502 LGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTST-MEHHHFDQCVMILNSESN-NIF 559
+ L+A HD+ H G ++ F T + LAILY+ T +E HH + S+ N NIF
Sbjct: 610 VAALLAAAAHDIGHPGKSSQFLCNTSNKLAILYNDLTVLESHHSALTFKVTLSDDNVNIF 669
Query: 560 QALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMT 619
+ L YK + + IL+T++ +F+ ++F+ L D F E L MM+
Sbjct: 670 KNLHADVYKSMRQNIIDMILATEMTKHFEHLARFVNLFDTSAF--LLPENVTLTKRMMIK 727
Query: 620 ACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFI 679
DVS +P+ + + +A+E+FDQ D EK + + M DR +P+ Q+GF+
Sbjct: 728 CADVSNPTRPFRLYVEWTRRIAEEYFDQTDEEKKKKLPVVMPMFDRACCC-IPKSQIGFV 786
Query: 680 DTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
+ I + + D F M + ++N +W++L E+
Sbjct: 787 EYIINDMMEAW-DAFIDMPEMVGYMSENYMKWKELNEQ 823
>UniRef50_Q57V52 Cluster: 3', 5'-cyclic nucleotide
phosphodiesterase, putative; n=3; Trypanosoma|Rep: 3',
5'-cyclic nucleotide phosphodiesterase, putative -
Trypanosoma brucei
Length = 676
Score = 121 bits (291), Expect = 9e-26
Identities = 78/283 (27%), Positives = 135/283 (47%), Gaps = 7/283 (2%)
Query: 434 TLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLK-TGKM 492
T + + +LV +F + L R++L V+ Y P YHN HA +V Q + ++ G
Sbjct: 394 TYTILYKLDLVARFQLDDATLQRFLLGVQSGYHPNPYHNSMHAADVTQVNYYIIFIAGMK 453
Query: 493 ERF-MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMI 550
ER + E LG ++A HD DH G NN F T+T + L+ LY+ S +E+HH +
Sbjct: 454 ERCQLRPEEQLGAVLAAAVHDFDHPGLNNNFHTRTNAYLSTLYNDRSILENHHIASVFQL 513
Query: 551 LNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKK 610
L S N+ L+ ++ V + +L+TD++ + +F + DW A ++
Sbjct: 514 LKHPSYNVLAPLNDEQFRTVRETMVEMVLATDMSNHGTILKRFQSRLVEAS-DWSANKQD 572
Query: 611 ELLC-GMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKD 669
L+ M + D+S +P+ + + +A EF+ QGD E+ + N M+R+ D
Sbjct: 573 VLVALSMSIKTADLSNCIRPYYIYSEWSSYIAQEFYKQGD-EEERSNLSISPFMNRKTSD 631
Query: 670 -ELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRW 711
+ P+ Q FI + P+ + + P + +NR W
Sbjct: 632 KDFPEGQKSFITYVVAPMMEAVVMFLPHLRFTLQLCENNRTAW 674
>UniRef50_A2E0V4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 438
Score = 121 bits (291), Expect = 9e-26
Identities = 55/181 (30%), Positives = 103/181 (56%), Gaps = 2/181 (1%)
Query: 456 RWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDH 515
R++ +++ Y+ V YHNWRHA++V Q + + E+ + E L+VA +C D +H
Sbjct: 198 RFLYAIRSMYKKVPYHNWRHAVDVTQFVTYQIMISGHEKVFTKFEF-NLVVAAICRDANH 256
Query: 516 RGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVV 574
G N + K E+PL ILY S ME HH + I++ E N+ L+ + ++ ++
Sbjct: 257 DGFTNIYNIKAETPLGILYKNQSVMETHHCSIAIQIMSHEETNLLATLNQDECNEIWSLI 316
Query: 575 ETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQH 634
IL+TD+A +F+ +F+++ D+ +F Q + + +L M++ D+S +++P+E+
Sbjct: 317 IQYILATDMARHFEILKRFIDIYDDSDFTTQRHDHRVMLLYMILKCGDISNVSRPFELVD 376
Query: 635 R 635
R
Sbjct: 377 R 377
Score = 39.9 bits (89), Expect = 0.28
Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 142 LSHSGSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSN 201
LS F D+ + + FCGI + NA+L+++S+ K+ I ++ +I E+ S
Sbjct: 2 LSEKSELLFDDEDIRMMTAFNVFCGISLYNAKLYQASLDLSKQLTIFTEMSSAIKEDSS- 60
Query: 202 LECLVTKIMTEARDLLKCERCAVFILDTD 230
+ + I+ A++ L ++I ++D
Sbjct: 61 -DQTLKSIIMNAKNTLGASGAVLYIYNSD 88
Score = 35.5 bits (78), Expect = 6.1
Identities = 15/56 (26%), Positives = 30/56 (53%)
Query: 346 FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSK 401
F + D+ + AF +FCG+ ++N ++Y+ + L + + E S S++ T K
Sbjct: 10 FDDEDIRMMTAFNVFCGISLYNAKLYQASLDLSKQLTIFTEMSSAIKEDSSDQTLK 65
>UniRef50_A2FET3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1135
Score = 120 bits (290), Expect = 1e-25
Identities = 80/328 (24%), Positives = 153/328 (46%), Gaps = 21/328 (6%)
Query: 405 DEIPSAETYNLYSFQFHDFDLT----------DEDTCRATLRMFLQCELVEKFHIPYDVL 454
D I A + F+D DLT D+ LR+F E+ +
Sbjct: 816 DMIRKANQLKIDELSFYDHDLTSKSFSIEKYNDQQIIELLLRVFESLEINNVLCSKTPKI 875
Query: 455 CRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKME-RFMSDLEILGLLVACLCHDL 513
+++ V K Y+ KYHNW HA+ Q ++++K GKM R ++ ++ L++ACL HD+
Sbjct: 876 VKFLEEVSKLYKNNKYHNWNHAVETVQLCYSIVKRGKMSPRAINPMQTTALILACLLHDI 935
Query: 514 DHRGTNNAFQTKTESPLAILYSTST-MEHHHFDQCVMILNSESNNIFQALSPRDYKDVMH 572
H GT+N + K +S L ++ +E+ + V +L S+ F ++ ++
Sbjct: 936 CHDGTSNEYHIKAKSSLYHVFGDDCPLENSSLTRSVRLLKSQP--FFVCINNEEF---WL 990
Query: 573 VVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEV 632
+ +L+TD+ Y + + + N FD + L +++T ++S + +P+
Sbjct: 991 FFKECLLATDIKKYEETIQNYQQCARN--FDSKNLIHSVSLAKLVITVANISNVVRPFSQ 1048
Query: 633 QHRIAKLVADEFFDQGD-LEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLS 691
++A+ + E + + L L + +Q E DELP +++ FI + PL K ++
Sbjct: 1049 AQQVAENLETETDETNEKLRTLGIKEQTFVYWKCES-DELPNIEMKFIQEVATPLIKAIT 1107
Query: 692 DTFPWMTPLRTGTADNRRRWQDLAEKVD 719
+FP + L T + +R WQ + ++
Sbjct: 1108 GSFPELNDLNTSLEETKRNWQQIISNLE 1135
>UniRef50_Q16J23 Cluster: Camp-specific 3,5-cyclic
phosphodiesterase; n=2; Culicidae|Rep: Camp-specific
3,5-cyclic phosphodiesterase - Aedes aegypti
(Yellowfever mosquito)
Length = 872
Score = 120 bits (289), Expect = 2e-25
Identities = 75/244 (30%), Positives = 123/244 (50%), Gaps = 11/244 (4%)
Query: 448 HIPYDVLCRWILS--VKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGL 504
H DV+ W L +++ Y YHN HA +V Q M L+ ++ +S LEI+
Sbjct: 142 HFNLDVVRVWKLFSLIEEGYHSTNPYHNSIHATDVTQAMHCFLQEKRILENLSPLEIMAS 201
Query: 505 LVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCV-MILNSESNNIFQAL 562
L+ + HDLDH G N F T + LA LY +TS +E+HH+ V +L S Q +
Sbjct: 202 LIGAVTHDLDHPGVNQPFLIATSNHLAALYENTSVLENHHWRSAVGCLLESGVAEQIQGI 261
Query: 563 SPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACD 622
P K + + IL+TD+ + S+F + + + D + +E + + + + D
Sbjct: 262 RPELEKQ----ISSLILATDITRQQEFISQFRDYLSHDTLDMRNKEHRHFILQIALKCAD 317
Query: 623 VSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTI 682
+S +PW++ + + V +EFF QGD E+ QLN ++ DR +P++Q GF +
Sbjct: 318 ISNPCRPWDISKKWSLKVCEEFFRQGDYER-QLNLPVTSLCDRH-STSVPKIQTGFFKFV 375
Query: 683 CLPL 686
PL
Sbjct: 376 VTPL 379
>UniRef50_UPI0000DB6B8B Cluster: PREDICTED: similar to
phosphodiesterase 7A isoform a; n=1; Apis mellifera|Rep:
PREDICTED: similar to phosphodiesterase 7A isoform a -
Apis mellifera
Length = 1148
Score = 120 bits (288), Expect = 2e-25
Identities = 67/248 (27%), Positives = 124/248 (50%), Gaps = 6/248 (2%)
Query: 443 LVEKFHIPYDVLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKMERFMSDLEI 501
L++ F++ + + +++ Y YHN HA +V Q M L+ K+ +++LEI
Sbjct: 68 LLQYFNLDVVTVWKLFAFIEEGYHSTNPYHNSIHATDVTQAMHCFLQEEKIRTHLTNLEI 127
Query: 502 LGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQ 560
+ L+A + HDLDH G N F T + LA LY +TS +E+HH+ + L + +
Sbjct: 128 MASLIAAVTHDLDHPGVNQPFLVATSNHLAALYQNTSVLENHHWRSAIGCL--LESGVSD 185
Query: 561 ALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTA 620
L ++ + + IL+TD+ + +F +D + + + + + + +
Sbjct: 186 QLPAHVRPELQRHISSLILATDITRQQEFLIRFKHYLDENLLEMKRADDRHFILQIALKC 245
Query: 621 CDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFID 680
D+S +PW++ + + V +EFF QGD E+ +LN + DR +P++Q GF
Sbjct: 246 ADISNPCRPWDISQKWSHKVCEEFFRQGDYER-RLNLPVTPLCDRH-TTSIPKIQAGFFK 303
Query: 681 TICLPLYK 688
+ PLY+
Sbjct: 304 FVVTPLYE 311
>UniRef50_Q6S998 Cluster: CAMP-specific phosphodiesterase; n=3;
Leishmania|Rep: CAMP-specific phosphodiesterase -
Leishmania major
Length = 631
Score = 120 bits (288), Expect = 2e-25
Identities = 76/274 (27%), Positives = 136/274 (49%), Gaps = 8/274 (2%)
Query: 442 ELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQ-TMFAMLKTGKMERF-MSDL 499
+ ++KF I + WI +V+ +Y YHN HA +V Q T F + + G +R +SD+
Sbjct: 356 DFLQKFKIDEQIALNWISAVEASYHGNPYHNSMHAADVLQITDFIITQGGLAKRCDLSDI 415
Query: 500 EILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNI 558
++ L+A HD DH G NN F KT S LA LY+ S +E+ H ++ + + NI
Sbjct: 416 QVFSALLAASIHDFDHPGINNNFHIKTGSYLATLYNDRSVLENLHVSSVFELMKNPAFNI 475
Query: 559 FQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFL-ELVDNGEFDWQAQEKKELLCGMM 617
+ S + +V + +L+TD+ + K + ++ ++ F A++ L +
Sbjct: 476 LASFSDEQHHEVRETMIEMVLATDMGSHGKYVASLKGKMQEHSSFTQTAEQ--NLCLAIA 533
Query: 618 MTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVG 677
+ D+S +P ++ R V+DEF+ QGD E+ L + MDR + L + Q+
Sbjct: 534 LKMADISNCGRPLDIYLRWGAKVSDEFYQQGDRER-NLGLECSPFMDR-LQPSLAKSQIA 591
Query: 678 FIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRW 711
F++ I P ++ +++ P M +N+ W
Sbjct: 592 FMNYIITPFFEQVAELLPDMRFAVALVEENKAYW 625
>UniRef50_Q9N2V9 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-6; n=3; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-6 - Caenorhabditis elegans
Length = 760
Score = 120 bits (288), Expect = 2e-25
Identities = 77/282 (27%), Positives = 138/282 (48%), Gaps = 6/282 (2%)
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKME 493
+++F + ++ + D+L RWILS++ +Y YHN HA +V Q L + +
Sbjct: 465 MKVFERWKVCDVLGCSDDLLHRWILSIEAHYHAGNTYHNATHAADVLQATSFFLDSPSVA 524
Query: 494 RFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMI-L 551
+++ + L+A HDLDH G NA+ T LAILY+ S +E+HH + L
Sbjct: 525 VHVNESHAVAALLAAAVHDLDHPGRGNAYLINTRQSLAILYNDNSILENHHIALAFQLTL 584
Query: 552 NSESN-NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKK 610
+N NIF +LS ++ + H + +L+TD++ +F+ +KF ++ + Q
Sbjct: 585 QHNANVNIFSSLSREEFIQMRHAMVEMVLATDISRHFEYLAKFNKMHVTDVPEEQRDTNS 644
Query: 611 ELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDE 670
+C M++ D+S A+ W + R A + +E+F+Q EK + + + DR +
Sbjct: 645 LTICDMLVKCADISNPAREWGLCQRWAHRIVEEYFEQTREEKEKGLPVTMEVFDRNTCN- 703
Query: 671 LPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
+P Q GFID + ++ F + L N +W+
Sbjct: 704 VPITQCGFIDMFAREAFATFTE-FAKLGELSDQLESNYEKWK 744
>UniRef50_A0EHP5 Cluster: Chromosome undetermined scaffold_97, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_97,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 908
Score = 119 bits (287), Expect = 3e-25
Identities = 71/281 (25%), Positives = 136/281 (48%), Gaps = 8/281 (2%)
Query: 414 NLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY--RPVKYH 471
NL ++ F D + + T +F +K+ + + ++++++++ Y R +H
Sbjct: 607 NLNNWCF-DITIQKDQIKHYTWALFHLLNYFDKYQMYKETFFQFLVAIEERYNSRRNPFH 665
Query: 472 NWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLA 531
N+ H VA + M+K ++ ++ E +++ LCHD+DH G N F+ S LA
Sbjct: 666 NFEHGFTVAHACYYMIKNKLLDEYLDQTEQFAAILSSLCHDIDHTGRTNGFEVARMSKLA 725
Query: 532 ILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKK 590
+ Y+ S +E+HH I+ E NI LS ++ V + + IL+TD+ +F
Sbjct: 726 VRYNDESVLENHHAAMAFKIMQREKYNILSNLSQEQFQKVRRFMVSNILATDMKKHFDLV 785
Query: 591 SKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDL 650
S NGE + + K +L G+++ CD++ K +E+ + + + +EF +Q +
Sbjct: 786 SSLEIKYKNGEMNIVNMDTKRVLSGLIVHTCDLTQPTKRFEITKKWSIRIQNEFDNQVEE 845
Query: 651 EKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLS 691
E+L + + LP+ ++ FI I PLY + S
Sbjct: 846 ERL----LGLPITQHLVCQNLPKQELSFIRNIIQPLYALTS 882
>UniRef50_Q22CV4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Tetrahymena thermophila SB210
Length = 1258
Score = 118 bits (285), Expect = 5e-25
Identities = 84/314 (26%), Positives = 150/314 (47%), Gaps = 9/314 (2%)
Query: 414 NLYSFQFHDFDLTDEDTCRATLRMFLQ-CELVEKFHIPYDVLCRWILSVKKNY--RPVKY 470
N+ + F+ F+L + T LQ + E IP DV ++ ++K Y + +
Sbjct: 834 NIDDWDFNVFELRSVEEKYTTAWNILQRAQYFESCSIPEDVFANFVKELQKQYDIKNNDF 893
Query: 471 HNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPL 530
HN+ H ++V Q+ + + K + + + ++I ++++ LCHD+ H G N F+ +S L
Sbjct: 894 HNFDHGVSVMQSCYMLSKCQRATQVLKPIDIFTVILSGLCHDVGHTGRTNNFEISVQSKL 953
Query: 531 AILY-STSTMEHHHFDQCVMIL-NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFK 588
AI Y S +E HH I+ S NI Q L P Y V + + IL TD+ +FK
Sbjct: 954 AIRYHDKSVLEQHHLATTFKIMKQSLDYNILQNLEPITYNQVRRSMISNILYTDIKQHFK 1013
Query: 589 KKSKFLELVDNGEFDWQAQEKK---ELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFF 645
F N + + + +LL GM++ D + AKP+ + + ++ V EF
Sbjct: 1014 LILDFETQWKNYDEQLKTTNSEGEIDLLTGMIIHTADFTGAAKPFPLSRQWSEKVNREFH 1073
Query: 646 DQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPW-MTPLRTGT 704
+Q E + +Q M D + + + + GF+ I LPL+K L+D + +
Sbjct: 1074 NQYIEEGKRGVEQTSFMKDLDILHVMAKAEKGFLSVIVLPLWKSLNDFYKGELNTQIEYL 1133
Query: 705 ADNRRRWQDLAEKV 718
D+ +W +L+++V
Sbjct: 1134 TDSINQWGELSQQV 1147
>UniRef50_A2DBZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1126
Score = 118 bits (283), Expect = 9e-25
Identities = 80/295 (27%), Positives = 139/295 (47%), Gaps = 14/295 (4%)
Query: 425 LTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRP-VKYHNWRHALNVAQTM 483
L+D + ++ F+ EL+ + L ++ ++NY +K+HN+ HAL+ Q +
Sbjct: 844 LSDSEKTECAMKFFINAELLNAIGGDLEKLTNFVTFTRENYNENLKFHNFEHALDFTQFV 903
Query: 484 FAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHH 542
F L K M+ + LL A L HD++H GTN F +T S L LY ST+E H
Sbjct: 904 FVCLTRNKFGNCMNVDQKAALLCASLLHDVNHDGTNTLFLNQTSSYLVDLYGKESTLERH 963
Query: 543 HFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEF 602
H + + I+ E + I KD V AIL+TD++ + + K L G+F
Sbjct: 964 HVSEALRIV--EKSGI-------TLKDKRFFV-NAILATDMSKFEENVQKVTVL--RGKF 1011
Query: 603 DWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAM 662
+ + + L+ ++M +V+ +P+ K + E+ + LE+ Q +
Sbjct: 1012 NKTDKTQVPLVATLLMMCGNVANTTRPFYFASECGKRILSEYQEISKLEEQNGIQNHQKI 1071
Query: 663 MDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
+ D LP++++ FI+ I LPL ++L D P + DN+ +W +K
Sbjct: 1072 CGKSITDPLPEIELAFINEIALPLLEILEDVSPDFKDFKVQCQDNKEQWTKETKK 1126
>UniRef50_Q13945 Cluster: 3',5'-cyclic AMP phosphodiesterase; n=37;
Coelomata|Rep: 3',5'-cyclic AMP phosphodiesterase - Homo
sapiens (Human)
Length = 606
Score = 118 bits (283), Expect = 9e-25
Identities = 80/288 (27%), Positives = 144/288 (50%), Gaps = 13/288 (4%)
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYRP-VKYHNWRHALNVAQTMFAMLKTGKMERF 495
+F + +L++ F I D ++++++ +Y V YHN HA +VAQ+ +L T ++
Sbjct: 241 IFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAV 300
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSE 554
+DLEIL + A HD+DH G +N F T S LA++Y+ S +E+HH +L E
Sbjct: 301 FTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEE 360
Query: 555 SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQA-------Q 607
+IF L+ + + + +V +L+TD++ + + +V+ +
Sbjct: 361 HCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYT 420
Query: 608 EKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREK 667
++ ++L M+ A D+S K E+ + + +EFF QGD E+ + + M D+
Sbjct: 421 DRIQVLRNMVHCA-DLSNPTKSLELYRQWTDRIMEEFFQQGDKER-ERGMEISPMCDKHT 478
Query: 668 KDELPQMQVGFIDTICLPLYKVLSDTF-PWMTPLRTGTADNRRRWQDL 714
+ + QVGFID I PL++ +D P + DNR +Q +
Sbjct: 479 A-SVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM 525
>UniRef50_Q53S13 Cluster: Putative uncharacterized protein PDE11A;
n=4; Deuterostomia|Rep: Putative uncharacterized protein
PDE11A - Homo sapiens (Human)
Length = 125
Score = 117 bits (282), Expect = 1e-24
Identities = 48/102 (47%), Positives = 73/102 (71%)
Query: 616 MMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQ 675
M+MTACD+ A+ KPWE+ ++A+LV EFF+QGD E+L+L P A+ DR +KDELP++Q
Sbjct: 2 MLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQ 61
Query: 676 VGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
+ +ID+IC+PLY+ L + P+ A NR +W++L +K
Sbjct: 62 LEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQK 103
>UniRef50_Q22000 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-4; n=7; Caenorhabditis elegans|Rep: Probable
3',5'-cyclic phosphodiesterase pde-4 - Caenorhabditis
elegans
Length = 674
Score = 117 bits (281), Expect = 2e-24
Identities = 83/304 (27%), Positives = 143/304 (47%), Gaps = 11/304 (3%)
Query: 434 TLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKME 493
T + Q L + F I L ++L+++ +YR YHN+ HA +VAQ+M +L + +
Sbjct: 370 TFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLT 429
Query: 494 RFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILN 552
+DLE+L + A HD+DH G N + + + LAI+Y+ S +E HH +L
Sbjct: 430 EVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQ 489
Query: 553 SESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVD------NGEFDWQA 606
+ + LS + +V +L+TD++ + + +V+ N
Sbjct: 490 DSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDK 549
Query: 607 QEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDRE 666
K + M+ D+S KP E+ + + + +E++ QGD EK +L + M DR
Sbjct: 550 YNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEK-ELGLEISPMCDRG 608
Query: 667 KKDELPQMQVGFIDTICLPLYKVLSD-TFPWMTPLRTGTADNRRRWQD-LAEKVDMGLTW 724
+ + QVGFID I PLY+ +D +P + +NR +Q + E+ D T
Sbjct: 609 NV-TIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDTARTV 667
Query: 725 IDHD 728
+ D
Sbjct: 668 TEDD 671
>UniRef50_A7AR41 Cluster: 3'5'-cyclic nucleotide phosphodiesterase,
putative; n=1; Babesia bovis|Rep: 3'5'-cyclic nucleotide
phosphodiesterase, putative - Babesia bovis
Length = 777
Score = 116 bits (280), Expect = 2e-24
Identities = 84/303 (27%), Positives = 144/303 (47%), Gaps = 10/303 (3%)
Query: 445 EKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLK-TGKMERFMSDLEILG 503
E + I V+ ++ ++ YR V YHN H VAQ + + TG +E +S L+
Sbjct: 472 EDYGIDRSVVVNFLYRIENQYRNVPYHNKMHGAMVAQKVLCLASYTGLLEH-LSILDEAL 530
Query: 504 LLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQAL 562
L+VA L HD+ H G NNAF +T P+A LY+ TS +E++H + +L + N+F
Sbjct: 531 LMVAALSHDVGHPGRNNAFFVRTHHPVAQLYNDTSVLENYHAASALRVLCTPGCNLFPDC 590
Query: 563 SPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACD 622
DY V + IL+TD F S+F+ +F ++ + L M+M A D
Sbjct: 591 ---DYDYVRSQIIEHILATDTVDQFHMISQFVLSCKRDDFTFEEYNSRILTSKMLMKAAD 647
Query: 623 VSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTI 682
V+A W + EF+ QG E++ A+ DR+ ++ + Q F+ +
Sbjct: 648 VAAPTMQWANSLEWVSRLLGEFYAQG-AEEVDYCIPISALCDRQHHEQSAKSQAAFLRIV 706
Query: 683 CLPLYKVLSDT-FPWMTPLRTGTADNRRRWQDLAEKVDMGLTWIDHDTIDKPVEEFTALN 741
PLY+ ++ P + + +N +W ++ +K + I+ + K + ++L
Sbjct: 707 VAPLYEAIASLGSPEIDAIMDQLEENAEKWNEM-DKAGTIIACIECEE-PKATVDISSLI 764
Query: 742 EPL 744
EPL
Sbjct: 765 EPL 767
>UniRef50_A7SYX3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 466
Score = 116 bits (278), Expect = 4e-24
Identities = 61/123 (49%), Positives = 83/123 (67%), Gaps = 9/123 (7%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAG--VRTLLCMPIVNANKDVIGVAQLIN 344
IA VA S + +NI D + D + ++G +++LCMPI N +++IGV QL+N
Sbjct: 345 IAFWVATSGQVVNIPDA--YSDDRFSPEADQASGFVTKSILCMPIYNREQNIIGVVQLMN 402
Query: 345 K-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDT 399
K F+E D SIFEAFAIFCGLGI+NT++YE ACKL+ KQKVA+E LSYHA+A +
Sbjct: 403 KLDGKPFSESDESIFEAFAIFCGLGINNTKLYEEACKLLTKQKVAMEVLSYHASAQPAEV 462
Query: 400 SKL 402
K+
Sbjct: 463 HKI 465
Score = 104 bits (250), Expect = 9e-21
Identities = 47/73 (64%), Positives = 61/73 (83%)
Query: 156 EVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKIMTEARD 215
EVF+ YLTFC IGI NAQLFE+S LE+KRNQ+LL LA+SIFEEQ+N++ V I+ +A+
Sbjct: 234 EVFKDYLTFCAIGITNAQLFETSELEFKRNQVLLQLAKSIFEEQTNVDDCVNNIIVQAQA 293
Query: 216 LLKCERCAVFILD 228
LL+CERC VF++D
Sbjct: 294 LLQCERCMVFLID 306
Score = 52.4 bits (120), Expect = 5e-05
Identities = 23/51 (45%), Positives = 35/51 (68%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTES 101
Y +F+ E D +G+ T+ ILCMPI N E +++GV Q++NK DG+ +ES
Sbjct: 362 YSDDRFSPEADQASGFVTKSILCMPIYNREQNIIGVVQLMNKLDGKPFSES 412
Score = 41.5 bits (93), Expect = 0.093
Identities = 17/33 (51%), Positives = 23/33 (69%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDV 83
Y +FN ++D +TGY T ILCMPI N+E +V
Sbjct: 203 YSDPRFNRDVDKKTGYTTHSILCMPIKNHEDEV 235
Score = 36.7 bits (81), Expect = 2.6
Identities = 27/127 (21%), Positives = 55/127 (43%), Gaps = 5/127 (3%)
Query: 54 IQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE--HTTESTLDHNYEPRP 111
+ F+ D + + +L P + D G+A + T G+ + ++ D + P
Sbjct: 314 VVFSKAFDIQFKEDEDAVLSTPSSYWSVDT-GIAFWV-ATSGQVVNIPDAYSDDRFSPEA 371
Query: 112 GQITRGPVASHWYSLYYFGNQRLYTYLRRKLSHSGSKEFSSRDVEVFRRYLTFCGIGIQN 171
Q + G V + + ++ + + ++ K FS D +F + FCG+GI N
Sbjct: 372 DQAS-GFVTKSILCMPIYNREQNIIGVVQLMNKLDGKPFSESDESIFEAFAIFCGLGINN 430
Query: 172 AQLFESS 178
+L+E +
Sbjct: 431 TKLYEEA 437
>UniRef50_O96077 Cluster: EFPDE3; n=1; Ephydatia fluviatilis|Rep:
EFPDE3 - Ephydatia fluviatilis
Length = 1054
Score = 115 bits (277), Expect = 5e-24
Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 6/208 (2%)
Query: 490 GKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCV 548
G + S LE+ +A HD DH G NAF T+SPLAILY+ + +E+HH
Sbjct: 657 GNVASAFSILEVFATYMAAAVHDFDHPGRTNAFLVATKSPLAILYNDRAVLENHHCAASW 716
Query: 549 MILNS-ESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVD---NGEFDW 604
+L S +N + + K ++ A+L+TDL M+F S F VD +G DW
Sbjct: 717 DLLTSVPEHNFLGDMEEAELKRFRFLLVEAVLATDLKMHFDLLSDFRAKVDPEEDGGIDW 776
Query: 605 QAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMD 664
++ + + M+M D+S K +E+ KL+ +EF+ QG+ +++ L P +D
Sbjct: 777 SSEVDRLTVMKMIMKMADISTPTKSYELHRAWTKLITEEFYQQGE-QEIVLGLPPTIFLD 835
Query: 665 REKKDELPQMQVGFIDTICLPLYKVLSD 692
R+ ++LP +Q+ FI + PL+ ++
Sbjct: 836 RKHPEKLPAVQLSFIQNLVSPLFHACAE 863
>UniRef50_Q4N6H0 Cluster: Putative uncharacterized protein; n=1;
Theileria parva|Rep: Putative uncharacterized protein -
Theileria parva
Length = 840
Score = 115 bits (276), Expect = 6e-24
Identities = 77/281 (27%), Positives = 136/281 (48%), Gaps = 9/281 (3%)
Query: 414 NLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNW 473
N ++F D+ T ++ L E F+IP DV+ ++ V+K Y V YHN
Sbjct: 551 NDWNFSILDY-FRQNPTGFISIGCVLLSEFQTHFNIPTDVIYSFLGLVEKCYNNVSYHNQ 609
Query: 474 RHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAIL 533
H + V Q + + + +S ++ L+++ LCHD+ H G NAF + LA L
Sbjct: 610 MHGVFVCQKLLCLSNFTNVYSRLSVIDRTILIISGLCHDIGHPGLTNAFFINSGHQLAHL 669
Query: 534 YS-TSTMEHHHFDQCVMILN-SESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKS 591
++ S +E+ H C + N +N+F L + K V + ILSTDL +F+ +
Sbjct: 670 FNDKSVLENFH---CCLTFNVLRQSNLFSFLDKEEMKIVRRKIIQLILSTDLEDHFQTIT 726
Query: 592 KFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE 651
+F V ++ + + + +C M++ A D+ + W + ++ + EF+ QG LE
Sbjct: 727 QF--RVRRASREFSVEGEIDTICKMLIKASDIGSSCMEWRLTLEWSQRLVQEFYTQG-LE 783
Query: 652 KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSD 692
+L L + D K + LP+ Q GF+ +PLY +++
Sbjct: 784 ELSLGLPITPLCDPNKHNHLPKAQSGFLAIFVIPLYTEIAN 824
>UniRef50_Q4RH59 Cluster: Chromosome undetermined SCAF15069, whole
genome shotgun sequence; n=3; Euteleostomi|Rep:
Chromosome undetermined SCAF15069, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 695
Score = 114 bits (274), Expect = 1e-23
Identities = 91/288 (31%), Positives = 145/288 (50%), Gaps = 38/288 (13%)
Query: 442 ELVEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTM-FAMLKTGKMERFMSD 498
+L+ +F IP L ++ +++ Y K YHN HA +V QT+ + +LKTG M ++++
Sbjct: 254 DLISRFKIPISALVSFVEALEVGYSKHKNPYHNLIHAADVTQTVHYLLLKTG-MVHWLTE 312
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTES--------PL--------------AILYST 536
LEI ++ A HD +H GT N F +T S P+ AILY+
Sbjct: 313 LEIFAMIFAAAVHDYEHTGTTNNFHIQTSSAKYTSCICPVQLQQDPKNEIKSDTAILYND 372
Query: 537 -STMEHHHFDQCVMILNSESN-NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFL 594
S +E HH +L + NI LS D++++ +V +L+TD++ +F++
Sbjct: 373 RSVLESHHVSAAYRLLQDDDEMNILYNLSKDDWRELRALVVEMVLATDMSCHFQQVKAMK 432
Query: 595 ELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KL 653
+ E +K + L ++ TA D+S AK W++ H + +EFF QGD E L
Sbjct: 433 NFLQQPE----GIDKPKALSLLLHTA-DISHPAKNWDLHHHWTTSLLEEFFRQGDKEADL 487
Query: 654 QLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP-WMTPL 700
L P+ DR K + Q Q+GFID I +P + VL+D +TPL
Sbjct: 488 GLPFSPLC--DR-KSTMVAQSQIGFIDFIVVPTFTVLTDMMERIVTPL 532
>UniRef50_A0E2C5 Cluster: Chromosome undetermined scaffold_74, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_74,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 975
Score = 114 bits (274), Expect = 1e-23
Identities = 77/256 (30%), Positives = 127/256 (49%), Gaps = 9/256 (3%)
Query: 443 LVEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTMFAML---KTGKMERFMS 497
L++++ IP D LC+++ V+ Y K +HN+ H ++V Q + A+L +S
Sbjct: 694 LIKEYDIPLDTLCQFLSEVEYKYNKKKNVFHNYDHGVSVMQNVHAILLQLHQTSNAAIIS 753
Query: 498 DLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESN 556
LL++ LCHD+ H G N F+ + S LAI Y S +E HH + + +L +
Sbjct: 754 TFNQFALLLSGLCHDVSHTGRTNTFEINSLSNLAIRYHDRSVLEQHHAAKSLKLLCVPAT 813
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGM 616
NI Q+ +++ + + IL TD+ +F F V F Q ++ K LL GM
Sbjct: 814 NILQSFKGEEFRKFRRMFISNILYTDITEHFNLIKNFESKVSESNFGQQDEDIK-LLSGM 872
Query: 617 MMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELPQMQ 675
++ D + AK +E+ + + V EF Q +LE KL Q P M D +K + + +
Sbjct: 873 IIHTSDFTGGAKQFELSKQWSFKVNKEFEQQYELEGKLGYPQLPY-MKDLQKLPVMAKQE 931
Query: 676 VGFIDTICLPLYKVLS 691
GF I PL++ +S
Sbjct: 932 AGFFKFIVRPLWQSMS 947
>UniRef50_O96078 Cluster: EFPDE4; n=1; Ephydatia fluviatilis|Rep:
EFPDE4 - Ephydatia fluviatilis
Length = 698
Score = 113 bits (273), Expect = 1e-23
Identities = 79/291 (27%), Positives = 141/291 (48%), Gaps = 17/291 (5%)
Query: 433 ATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKM 492
A +F +L + I V +I +++ Y YHN HA +V +LK +
Sbjct: 377 AAYHVFKARDLFSEMKIVPSVFLNFISTIESKYHSNPYHNALHAADVLLATNHLLKAKAL 436
Query: 493 ERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMIL 551
E + LE+ LVA + HD+DH G NN F TE PLAILY+ S +E+HH ++
Sbjct: 437 EPIFTQLEVFAALVAAIIHDVDHPGRNNQFLVSTEDPLAILYNDESVLENHHLALAFELM 496
Query: 552 NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVD------NG--EFD 603
+ N ++ + ++ +L+TD++ +FK + L++ NG + D
Sbjct: 497 KDPTCNFLESTCKSQKQAFRKLIIDMVLATDMSRHFKYLGQLKTLLESNKVANNGLLQLD 556
Query: 604 WQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAM 662
+ ++ E+L G++ A D+S K + + + ++ + +E + QGD E KL + P+
Sbjct: 557 -KYHDRVEVLQGLLHCA-DLSNQTKSFHIASQWSQRIMEESYRQGDEERKLGIPVNPLG- 613
Query: 663 MDREKKDELPQMQVGFIDTICLPLYKVLSD-TFPWMTPLRTGTADNRRRWQ 712
++ + + QV FID I PL++ ++ +P + D R +WQ
Sbjct: 614 ---DRSVSIEKCQVTFIDYIVYPLWETWAELVYPDAQDIVCSLMDTRDQWQ 661
>UniRef50_A0DIM1 Cluster: Chromosome undetermined scaffold_52, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_52,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 779
Score = 113 bits (273), Expect = 1e-23
Identities = 87/335 (25%), Positives = 156/335 (46%), Gaps = 25/335 (7%)
Query: 402 LCQDEIPSAETYNLYSFQFHD--------FDLT----DEDTCRATLRMFLQCELVEKFHI 449
+ + E+ + + ++LY+ +D FD+T + R T +F C ++ + I
Sbjct: 445 IIETELTNIKKFDLYTLDANDISNLSDYSFDITVVQDKHEQLRYTWALFHLCNFIDLYQI 504
Query: 450 PYDVLCRW--ILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVA 507
+V ++ I+ K +YR +HN+ H VA + ++K+ M ++ L++
Sbjct: 505 NKEVFYQFTVIVQEKYSYRQNPFHNYDHGFTVAHACYYIIKSKSMNQYFDKFIQFTALLS 564
Query: 508 CLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRD 566
LCHD+DH G NN F+++ S LA+ Y+ S +E+HH IL E NI +LS
Sbjct: 565 ALCHDIDHTGRNNHFESQKLSKLALRYNDESVLENHHASVMFKILQKEKYNILSSLSQDQ 624
Query: 567 YKDVMHVVETAILSTDLAMYFKKKSKFLELVDN---GEFDWQAQEKKELLCGMMMTACDV 623
+ IL TD+ +F + K LEL + E Q +E K+ L ++ CD+
Sbjct: 625 CQIFRKYAIANILGTDMKKHF-EIVKLLELKLSKLPDEPFIQKEEDKKFLSSAIVHTCDL 683
Query: 624 SAIAKPWEVQHRIAKLVADEFFDQGDLEK---LQLNQQPIAMMDREKKDELPQMQVGFID 680
+ +K +++ + + +A EF DQ EK L + Q + + L + ++ FI
Sbjct: 684 TMQSKTFKMAQKWSNRIATEFSDQVAEEKQLSLPITQHFLPLGTPNFNQLLAKQEISFIK 743
Query: 681 TICLPLYKVLSDTFP--WMTPLRTGTADNRRRWQD 713
I P Y + + PL+ DN + W++
Sbjct: 744 FIVKPAYDLTAQVLQTGLEVPLK-NLEDNLKEWEN 777
>UniRef50_A0CZ03 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_31,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 692
Score = 113 bits (272), Expect = 2e-23
Identities = 79/284 (27%), Positives = 141/284 (49%), Gaps = 7/284 (2%)
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMER 494
L +F L + F I V+ + V + Y+ YHN HA +VAQT +L K
Sbjct: 398 LFLFENYNLYDVFLIKPKVVRSYFEEVMRGYQDNPYHNRVHAQDVAQTCNFLLNRCKFIE 457
Query: 495 F--MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMIL 551
+ + +I +L+A HD H G NAF +++ LA+ Y+ S +E H QC I
Sbjct: 458 IGQLDEQDIACVLIAGAIHDYGHPGLTNAFLINSKNELALTYNDQSVLEMFHPSQCFKIA 517
Query: 552 -NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKK 610
++ NIF++L+ + Y+ + + + +LSTD+A + + + V +F+ ++K+
Sbjct: 518 WTNQKANIFESLTFQKYRRIRESIISMVLSTDMAHHASELAITNSRVAAPDFEPYGKDKQ 577
Query: 611 ELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDE 670
L+ +++ + DVS K +E+ + + V EF+ QGD E+ +L PI+ +
Sbjct: 578 RLM-DLVVHSSDVSNPTKSFEIYKQWTERVLTEFWLQGDKER-ELGL-PISYLCNRYTTN 634
Query: 671 LPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDL 714
+ + Q+GFID + P + + P P N+ +WQ+L
Sbjct: 635 MAEAQLGFIDYVVKPTFSCVQGFLPAFEPYLENLDKNKAKWQEL 678
>UniRef50_A2GFY4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 457
Score = 113 bits (271), Expect = 3e-23
Identities = 71/279 (25%), Positives = 129/279 (46%), Gaps = 10/279 (3%)
Query: 411 ETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKY 470
+ Y + F FD ++ + +F Q + I ++ R++ ++ Y V Y
Sbjct: 154 DAYQNFMFTIERFD--NDSLFEIVVCLFSQIIKRSQLDIDFETFVRFLYKIRSLYNDVPY 211
Query: 471 HNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPL 530
HNWRHA + Q ++ L +E F+ ++ L+ A +CHD+ H G +N F + S
Sbjct: 212 HNWRHACDACQFVYFALLQKPIEHFIQPIDYFSLMTAAICHDVGHNGRSNDFHRQVNSKY 271
Query: 531 AILYSTS--TMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFK 588
A ++ +E+HH + L++E + Q + + V IL+TD++
Sbjct: 272 AQESGSNQPPLEYHHQKITIEFLSNEFSKSIQTFNDETRRIYFKFVSNIILATDMS---- 327
Query: 589 KKSKFLELVDNGEFDWQAQEKKELL-CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQ 647
K ++ +N ++ E + LL C +M D+S +P+ ++ + +E++ Q
Sbjct: 328 KHQDYIVSFNNIAGSYKDTEDERLLACQAIMKLADLSNTCRPFGEAATMSAQLQEEWYTQ 387
Query: 648 GDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPL 686
GD E+L+ + DR K LPQ QVGF + L L
Sbjct: 388 GD-EQLKRGLEITKGFDRNNKTPLPQGQVGFYKYVTLKL 425
>UniRef50_A2DM77 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1072
Score = 113 bits (271), Expect = 3e-23
Identities = 96/404 (23%), Positives = 178/404 (44%), Gaps = 15/404 (3%)
Query: 299 NISDVEQWLRDNNMSAG--ENSAGVRT--LLCMPIVNANKDVIGVAQLINK---FTEGDV 351
NIS + +++ M + +N+ +T + P+ + IGV Q+ N F D+
Sbjct: 647 NISRITNDAQNDKMFSAILDNATNTKTNSFISTPMYRLDGKFIGVIQICNAPHGFDIKDL 706
Query: 352 SIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSAE 411
+ + C I + + A K Q + +S L + E
Sbjct: 707 RLLQVIGAICTHPIEVKDLSQEAVK-GEMQTTMSKFISETEMNEFSIPHMLVYSKQEDTE 765
Query: 412 TYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYH 471
NL +F + + T + +F Q L++KF I L +I + ++ V +H
Sbjct: 766 ANNL---EFASYMWDYDTTFKVVFAVFNQFNLMKKFQITASTLFNFIFEARSEFQIVPFH 822
Query: 472 NWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLA 531
N+ A++ Q + ++ G +ER + E L L++A LCHD+ H G +N + +T SP+
Sbjct: 823 NFYLAIDQLQFLNILINEGNLERILQPTEFLALIIATLCHDMGHDGVDNKYLRETNSPIF 882
Query: 532 ILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKS 591
+ E+HHF ++I + + +F ++ +D + V+ ILS++ +K
Sbjct: 883 AAFPEYPNENHHF--VILIEVIKRSGLFNNINLQDTTAIWGVIRDLILSSNCDPKELQK- 939
Query: 592 KFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE 651
+ E+V NG D Q +++L +++ CD S + W+V + + + E F QGDL
Sbjct: 940 ETNEIVMNGPPDMQNPRTRKVLMRLLVNICDWSYSMRSWDVCDKWSFNLFAEHFMQGDL- 998
Query: 652 KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
+L +P R K E + V I+ + L ++S P
Sbjct: 999 MTELGLKPDEHYLRGKPVEKQKETVWCIEEELIRLTTLISKIVP 1042
Score = 35.1 bits (77), Expect = 8.1
Identities = 14/40 (35%), Positives = 25/40 (62%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
+F+S D +KT +L +PI + +V+GV Q++N+ D
Sbjct: 498 EFDSSFDNMMNFKTLSVLSIPIFDQRKNVIGVVQLLNRKD 537
>UniRef50_A2DM90 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 457
Score = 112 bits (269), Expect = 4e-23
Identities = 85/343 (24%), Positives = 154/343 (44%), Gaps = 18/343 (5%)
Query: 381 QKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQ 440
++ + C Y + E S Q++I + + Y F ++ + D+ ++ F
Sbjct: 128 EETVINC-RYDFSTVLEHVSTFSQEDI---DRFRSYKFSV---EVLNTDSVFESIFSFFY 180
Query: 441 CELVEKFHIPYD--VLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSD 498
+++ IP D + +I+ + +Y V YHNWRHA + Q +F ++ +E +
Sbjct: 181 -SILKDTDIPVDWNEIIAFIVEAQSHYNNVPYHNWRHATDATQFVFYLITMPHVEEMLPP 239
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTS--TMEHHHFDQCVMILNSESN 556
L+ LL++ +CHDL+H G N + K S + +E+HH +++
Sbjct: 240 LDRFALLLSVICHDLEHNGHTNDYHRKVNSEFSQEAGPDLPPLENHHQKLAKVLIQKHLK 299
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDN-GEFDWQAQEKKELLCG 615
+ L+ +++ + I STD+ K K ++V N G+FD E + L C
Sbjct: 300 YTLEHLTDEQKENMFRFITEIIFSTDMG---KHKFYLEKIVANIGKFDGSI-ELRILTCQ 355
Query: 616 MMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQ 675
+M D+S +P++ ++AK + DE+F QGD EK +L MDR+ LP+ Q
Sbjct: 356 AIMKLADLSNTCRPFDDSCKMAKRLNDEWFIQGDDEK-KLGLPISNGMDRDHPTPLPKGQ 414
Query: 676 VGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKV 718
+GF L + F + N W+ LA ++
Sbjct: 415 IGFYKFCTQQLLEADQKFFGCFQDIGNQFFSNLSTWEKLASEL 457
>UniRef50_UPI0000519BD4 Cluster: PREDICTED: similar to
phosphodiesterase 8A; n=1; Apis mellifera|Rep:
PREDICTED: similar to phosphodiesterase 8A - Apis
mellifera
Length = 820
Score = 111 bits (268), Expect = 6e-23
Identities = 95/339 (28%), Positives = 162/339 (47%), Gaps = 29/339 (8%)
Query: 422 DFDLTD-EDTCRATLRMFLQCELVEKFHIPYDVLCR------WILSVKKNYRPV-KYHNW 473
DFD+ E +FL ++ F +P + C W++ ++ NY +YHN
Sbjct: 479 DFDIFKLEILTEKRALLFLGMTIMNLFRVPARLGCEEKIVQNWLIVIEANYDITNRYHNS 538
Query: 474 RHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAIL 533
HA +V Q ++T ++++ + L+ + L+A HD+DH G ++ F +++ LAIL
Sbjct: 539 THAADVLQAAAMFMQTERLKQVLEPLDEVATLIAAAAHDIDHPGRSSQFLCNSDNKLAIL 598
Query: 534 YSTST-MEHHHFDQCVMILNSESN-NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKS 591
Y+ T +E HH + S+ N NIF+ L YK V V IL+T++ +F+ +
Sbjct: 599 YNDLTVLESHHAALTFKLTLSDDNVNIFKNLERDTYKQVRQSVIDMILATEMTKHFEHLA 658
Query: 592 KFL--------ELVDNG--EFDWQA---QEKKELLCGMMMTACDVSAIAKPWEVQHRIAK 638
KF+ E+ G + D A E L+ M++ DVS +P + A+
Sbjct: 659 KFMNAFSTRIPEMYIEGSQDLDLSAAILPENVILVKRMIIKCADVSNPTRPLKYCVEWAR 718
Query: 639 LVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMT 698
+A+E+F Q D EK QL+ + M +P+ Q+GFID I + + D F M
Sbjct: 719 RIAEEYFSQTDEEK-QLHLPVMMPMFDRITCSIPRAQIGFIDFIINDMVEAW-DVFINMP 776
Query: 699 PLRTGTADNRRRWQDLAEKVDMGLTWI-DHDTIDKPVEE 736
+ N +W++ EK G+T + D + I + + E
Sbjct: 777 EIVGFMRQNYDKWKEYNEK---GITTLQDIEKIQEAIPE 812
>UniRef50_A0E1V7 Cluster: Chromosome undetermined scaffold_74, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_74,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1007
Score = 111 bits (266), Expect = 1e-22
Identities = 73/250 (29%), Positives = 122/250 (48%), Gaps = 11/250 (4%)
Query: 445 EKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTMFAMLK--TGKMER-FMSDL 499
+ F +P D L +++ ++ Y YHN+ H + V Q + +K T ++++ F +++
Sbjct: 720 QMFALPQDKLINFLIEMESQYNMNNNPYHNFDHGVAVMQAVNCFIKSLTNQLDQQFFNNI 779
Query: 500 EILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTST-MEHHHFDQCVMILNSESNNI 558
LL++ LCHD+ H G NA++ + S LAI Y +E HH + IL + NI
Sbjct: 780 TKFCLLLSALCHDVAHTGKTNAYEANSISQLAIRYHDKVILEQHHAATTIKILRDDQTNI 839
Query: 559 FQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMM 618
S +D++ + + ILSTD+ +FK +F ++ D E LLCGM+
Sbjct: 840 LCNFSDQDFRTFRKQLISNILSTDMQEHFKMLKEFESRIEQYGND---PEDLSLLCGMIT 896
Query: 619 TACDVSAIAKPWEVQHRIAKLVADEFFDQ-GDLEKLQLNQQPIAMMDREKKDELPQMQVG 677
A D + A+ W + + E+ Q + K QQP M D +K + + ++G
Sbjct: 897 HAADFNGTARKWPQSRLWSDKINQEYRAQYAEEGKKGYPQQPF-MKDLDKLHVMSKNEIG 955
Query: 678 FIDTICLPLY 687
FI I PLY
Sbjct: 956 FIKVIVRPLY 965
>UniRef50_UPI000150A9A4 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 929
Score = 110 bits (265), Expect = 1e-22
Identities = 81/301 (26%), Positives = 145/301 (48%), Gaps = 12/301 (3%)
Query: 426 TDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY--RPVKYHNWRHALNVAQTM 483
T ED R MF ++K I +V +++ ++ Y R +HN++HA+ V+
Sbjct: 612 TTEDKLRYAWSMFHLAGFMDKLKIDKEVFLKFLQLLQHKYDKRQNPFHNFQHAIAVSHAT 671
Query: 484 FAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHH 542
+ + + R++ LE LL + L HD+ H G NAF+ T S LAI ++ S +E+H
Sbjct: 672 YFFINAKFLARYLDYLEQFTLLFSSLGHDVSHTGRTNAFEVATLSKLAIKFNDESVLENH 731
Query: 543 HFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF----LELVD 598
H I+ + +NIF+ LS D K++ + ILSTD+ + + +F L
Sbjct: 732 HSSTLFKII--QKHNIFEQLSNEDVKNIRKYCISNILSTDMKKHQELTKQFEIKLTYLKQ 789
Query: 599 NGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQ-GDLEKLQLNQ 657
G +++ K+L+CG ++ D++ K +E+ + + EF Q + E L L
Sbjct: 790 EGTDLIKSEADKKLMCGFLVHVADLTGPTKCFELAKEWSMRICKEFTLQVQEEEHLGLPV 849
Query: 658 QPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSD-TFPWMTPLRTGTADNRRRWQDLAE 716
P ++ E + + + + F I LPLY VLS+ P + +N +W+ + +
Sbjct: 850 TPY-LVGLESMEIISKQEGNFAKIIVLPLYSVLSEFAGPEFKQMVKNCENNISQWEKIHQ 908
Query: 717 K 717
+
Sbjct: 909 E 909
>UniRef50_A0CG66 Cluster: Chromosome undetermined scaffold_179, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_179, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1056
Score = 110 bits (264), Expect = 2e-22
Identities = 81/334 (24%), Positives = 147/334 (44%), Gaps = 12/334 (3%)
Query: 369 QMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDE 428
QM K +Q L S + E+ L D + T + +F+ F D
Sbjct: 695 QMLSKTIKAFRQQAAKLRIKSIESALEIEEDDDL--DSLHQDGTID--KLEFNIFSYKDN 750
Query: 429 DTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTMFAM 486
+ + + + +E + + DVL ++I V++ Y K +HN+ H + V Q+ +
Sbjct: 751 MKTKLVYHIIKKNDWIENYDMNRDVLMKFIKEVERKYNKRKNPFHNFDHGITVMQSCNFL 810
Query: 487 LKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFD 545
+ ++S++ +++ LCHD+ H G N F+ ++S LA Y S +E+HH
Sbjct: 811 CSLPRAHEYISEIVYFATVISGLCHDISHTGRTNQFEINSKSKLATRYLDKSPLENHHAA 870
Query: 546 QCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFD-- 603
+ +L + NI Q L+ D + IL TD+ +F F + V G+ +
Sbjct: 871 VTLKLLKQDKYNILQGLNAEDLAIFRQTLIENILFTDIKQHFGLIKDFEQRVKEGKENQE 930
Query: 604 ---WQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPI 660
Q +L GM++ D S AK +E+ ++ V EF Q D E +
Sbjct: 931 RVFGQVDGDVKLFTGMIVHTSDFSGAAKVFELSKAWSEKVNMEFQAQFDEEGTRKLISTP 990
Query: 661 AMMDREKKDELPQMQVGFIDTICLPLYKVLSDTF 694
M D +K++ + + ++GF I PL+ L++ +
Sbjct: 991 FMKDLDKQEIMAKNEMGFFKVIVRPLWASLNEFY 1024
>UniRef50_UPI00006CF33D Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 354
Score = 109 bits (262), Expect = 3e-22
Identities = 71/235 (30%), Positives = 129/235 (54%), Gaps = 11/235 (4%)
Query: 459 LSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGT 518
LS K +YR +HN+ H + VA ++ ++K G + ++ LE LL + LCHD+DH G
Sbjct: 84 LSNKYDYRGNPFHNFDHGITVAHGIYYIIKQGITNKHLNQLEKFSLLFSALCHDVDHTGH 143
Query: 519 NNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVM-HVVET 576
+NA++T ++S L LY + S +E HH+ Q + I ++ +F ++ P+D +M ++
Sbjct: 144 SNAYETNSKSELFTLYGNESPLEKHHYAQTIQI--ADQCGLFDSI-PQDQLVIMKKYIQH 200
Query: 577 AILSTDLAMYFKKKSKFLE-LVDNGEFDWQAQEKKEL-LCGMMMTACDVSAIAKPWEVQH 634
IL+TD++ + + ++F E L + D E++++ LCG ++ A D+ A + + +
Sbjct: 201 NILATDMSKHNQIMNEFKENLPSLLKEDLAITEQQKINLCGALVHAADIGAPTRDFSISK 260
Query: 635 RIAKLVADEFFDQGDLEKLQLNQQPIA--MMDREKKDELPQMQVGFIDTICLPLY 687
+ +A EF Q +LE Q N P+ D +K L ++GFI+ P +
Sbjct: 261 EWSLRIAKEFTAQLELE--QQNNLPVTPFYKDLDKYLTLATNEIGFINFFIKPFW 313
>UniRef50_Q6NNF2 Cluster: SD02170p; n=9; Diptera|Rep: SD02170p -
Drosophila melanogaster (Fruit fly)
Length = 914
Score = 109 bits (262), Expect = 3e-22
Identities = 84/292 (28%), Positives = 140/292 (47%), Gaps = 11/292 (3%)
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFAMLK--TGK 491
+ MF + ++ +I +V W+ ++ +YR YHN HA +V Q A + T K
Sbjct: 603 MEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNK 662
Query: 492 MERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTST-MEHHHFD-QCVM 549
M +E L+A HD+DH G ++AF + LA+LY+ T +E+HH +
Sbjct: 663 DMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKL 722
Query: 550 ILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGE-FDWQAQE 608
L + NIF+ L YK + IL+T++ +F+ +KF+ + E D Q
Sbjct: 723 TLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNPQT 782
Query: 609 KKE---LLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDR 665
+E L+ M++ DVS A+P + A+ +A+E+F Q D EK + + M DR
Sbjct: 783 DEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDR 842
Query: 666 EKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
+P+ Q+GFI+ I + ++F M L T N +W+ E+
Sbjct: 843 -ATCSIPKSQIGFIEYIIQDMMHAW-ESFIDMPQLITYMQINYSQWKKYDEQ 892
>UniRef50_A0EGK4 Cluster: Chromosome undetermined scaffold_95, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_95,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 756
Score = 109 bits (261), Expect = 4e-22
Identities = 76/260 (29%), Positives = 124/260 (47%), Gaps = 9/260 (3%)
Query: 434 TLRMFLQCELVEKFHIP-YDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKM 492
++ +F + + + I D++ + L + Y YHN HAL+VA + L G +
Sbjct: 446 SINLFKRFRIAQTLKITKQDMIGDFALKLFTQYHNNLYHNSLHALDVANSTAFFLNNG-L 504
Query: 493 ERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMIL 551
+ + + E L+V+ L HDL H G NN F T LA+LY+ S +E++H IL
Sbjct: 505 DAQLDEFEFACLIVSSLAHDLGHPGLNNGFMTTNRCKLALLYNDQSVLENYHSFLLFQIL 564
Query: 552 NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKE 611
E N+ Q L D K IL TDL +F+ ++F +D E K
Sbjct: 565 QQEQFNLIQNLGLPDQKGFRKYCLNLILDTDLTKHFQLMNRFQNYLDLSE---SQVTDKS 621
Query: 612 LLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDEL 671
L+ + + DV AK ++ ++ + +EFF QGDLE + PI+ M ++K +
Sbjct: 622 LVMSICIKCADVGHGAKQLKMHKLWSRRIIEEFFLQGDLE--DYLKVPISPM-CDRKQSV 678
Query: 672 PQMQVGFIDTICLPLYKVLS 691
+ Q GF+ I LP++ +
Sbjct: 679 VKSQEGFLKAIVLPMFNAFA 698
>UniRef50_Q4T098 Cluster: Chromosome undetermined SCAF11274, whole
genome shotgun sequence; n=4; Tetraodontidae|Rep:
Chromosome undetermined SCAF11274, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 601
Score = 108 bits (259), Expect = 7e-22
Identities = 68/211 (32%), Positives = 115/211 (54%), Gaps = 10/211 (4%)
Query: 493 ERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMIL 551
+ ++++LEI + A HD +H GT N F +T S +++LY+ + E+HH +L
Sbjct: 258 QHWLTELEIFATIFAAAIHDYEHTGTTNNFHIQTRSDISLLYNDHAVQENHHVSAVYRLL 317
Query: 552 -NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKK 610
++ NI LS D++++ +V +L+TD++ +F++ L+ E A +K
Sbjct: 318 QTNDDTNILSNLSKDDWRELRALVVEMVLATDMSCHFEQIKVMKGLLQQPE----AIDKA 373
Query: 611 ELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDE 670
+ L ++ TA D+S AKPW + HR + +EFF QGD E ++L + DR K
Sbjct: 374 KALSLLLHTA-DISHPAKPWSLHHRWTFSLLEEFFRQGDKE-VELGLPFSPLCDR-KSTM 430
Query: 671 LPQMQVGFIDTICLPLYKVLSDTF-PWMTPL 700
+ Q Q+GFID I P + V+++ MTPL
Sbjct: 431 VAQSQIGFIDFIVEPTFTVMTEMIEKIMTPL 461
Score = 36.3 bits (80), Expect = 3.5
Identities = 18/52 (34%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 442 ELVEKFHIPYDVLCRWILSVKKNYRPVK--YHNWRHALNVAQTM-FAMLKTG 490
+L+ +F +P L ++ S++ Y + YHN HA +V QT+ + +LKTG
Sbjct: 161 DLINRFKVPVSALILFVDSLEMGYSKHRNPYHNLTHAADVTQTIHYLLLKTG 212
>UniRef50_Q9W4T4 Cluster: cAMP-specific 3',5'-cyclic
phosphodiesterase, isoform I; n=38; Coelomata|Rep:
cAMP-specific 3',5'-cyclic phosphodiesterase, isoform I -
Drosophila melanogaster (Fruit fly)
Length = 1209
Score = 108 bits (259), Expect = 7e-22
Identities = 81/313 (25%), Positives = 145/313 (46%), Gaps = 12/313 (3%)
Query: 411 ETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY-RPVK 469
+T+ + F +F + TC A +F EL+ IP ++ +++ +Y +
Sbjct: 811 DTWGIQIFSIGEFSVNRPLTCVA-YTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNP 869
Query: 470 YHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESP 529
+HN HA +V Q+ +L T +E + LE+ G L A HD+DH G N F + S
Sbjct: 870 FHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSE 929
Query: 530 LAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFK 588
LA++Y+ S +E+HH +L ++ +IF + + + + +V +LSTD++ +
Sbjct: 930 LALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMS 989
Query: 589 KKSKFLELVD------NGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVAD 642
+ +V+ +G + + ++ D+S KP + R L+ +
Sbjct: 990 LLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLME 1049
Query: 643 EFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSD-TFPWMTPLR 701
EFF QGD E+ + M DR + + QVGFID I PL++ +D P +
Sbjct: 1050 EFFLQGDKER-ESGMDISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDIL 1107
Query: 702 TGTADNRRRWQDL 714
+NR +Q +
Sbjct: 1108 DTLEENRDYYQSM 1120
>UniRef50_A7AS42 Cluster: 3'5'-cyclic nucleotide phosphodiesterase,
putative; n=1; Babesia bovis|Rep: 3'5'-cyclic nucleotide
phosphodiesterase, putative - Babesia bovis
Length = 485
Score = 107 bits (257), Expect = 1e-21
Identities = 69/250 (27%), Positives = 121/250 (48%), Gaps = 5/250 (2%)
Query: 445 EKFHIPYDVLCRWIL-SVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILG 503
+K H ++ L +L S++ Y P YHN H VA +LK +E++++ LE
Sbjct: 184 DKIHPDFNKLITPVLNSIQDVYLPNPYHNALHGACVAHMSCVLLKALSLEQYLTPLEQFA 243
Query: 504 LLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQAL 562
L+A L HD H G NAF T++PLA++Y+ S +E++H I+ ++ + F
Sbjct: 244 YLIAALGHDAGHPGKTNAFLRSTQNPLALIYNDASILENYHASLVCHIIRAK-EDFFGLF 302
Query: 563 SPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLC-GMMMTAC 621
+ +D++ + + +L+TD+ +F + E +G FD+ + C +++
Sbjct: 303 NQQDWEIIRKRIIQLVLATDMMTHFTHVNNVKERRLSGTFDYVNNPEDLWFCLVLLVKTA 362
Query: 622 DVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDT 681
D+ PW + DEF QGD E+L L+ + DR + ++P Q+GF
Sbjct: 363 DIGHNFLPWCEHLPWTNALFDEFHMQGDEERL-LSLPLLLFFDRTRSADIPDSQLGFFQG 421
Query: 682 ICLPLYKVLS 691
PL L+
Sbjct: 422 FTSPLIDELT 431
>UniRef50_Q388U6 Cluster: 3', 5'-cyclic nucleotide
phosphodiesterase, putative; n=2; Trypanosoma
brucei|Rep: 3', 5'-cyclic nucleotide phosphodiesterase,
putative - Trypanosoma brucei
Length = 620
Score = 106 bits (255), Expect = 2e-21
Identities = 69/258 (26%), Positives = 123/258 (47%), Gaps = 8/258 (3%)
Query: 444 VEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERF--MSDLEI 501
+ KF I + W+ +V+ Y YHN HA +V +L G + ++D ++
Sbjct: 344 LRKFEINERIFLNWLSAVEGGYHANPYHNSMHAADVLHITHYLLSKGGLAELCKLNDRQV 403
Query: 502 LGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQ 560
L L A HD +H G NN F T++ A LY+ S +E+ H ++ + + NI
Sbjct: 404 LAALFAAAIHDYNHPGINNNFSILTQTYNATLYNDRSVLENMHVASVFELMRNPALNILA 463
Query: 561 ALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF-LELVDNGEFDWQAQEKKELLCGMMMT 619
S ++D + V +L+TD++++ K ++F L + F + L M +
Sbjct: 464 CFSEEHWRDFRNTVIDMVLATDMSLHEKYMTQFKRRLSEKRPFTEDCDQ--NLALAMALK 521
Query: 620 ACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFI 679
D+S +P + + ++ V+DEF+ QGD E+ L MDR+ + + Q FI
Sbjct: 522 LADISNCCRPLPLYLKWSERVSDEFYTQGDRER-SLGMSCSPFMDRQ-TPMIAEGQTSFI 579
Query: 680 DTICLPLYKVLSDTFPWM 697
+ I +P +V+++ P M
Sbjct: 580 NYIFIPFLEVMAEFLPSM 597
>UniRef50_A7SVX8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 844
Score = 106 bits (255), Expect = 2e-21
Identities = 75/299 (25%), Positives = 138/299 (46%), Gaps = 17/299 (5%)
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNY-RPVKYHNWRHALNVAQTMFAMLKTGKME 493
L++ + + EK +I D + W+ ++ NY R YHN HA +V L +++
Sbjct: 544 LKILNRFRVCEKLNISEDYVKNWLQLIEANYHRKNAYHNSTHAADVLHATAVFLAKERVK 603
Query: 494 RFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCV-MIL 551
+ L+ + L+A + HD+DH G N+F S LAILY+ + +E HH +
Sbjct: 604 AVLEPLDEVASLIAAIVHDVDHPGYTNSFLCNAGSELAILYNDIAVLESHHAALAFKLTA 663
Query: 552 NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFD-------- 603
+ +NIF L +++ V + +++T++ +F+ SKF+ ++
Sbjct: 664 RDDKSNIFSNLDVEEFRTVRQAIIDMVMATEMTRHFEHLSKFVNSINKRRSSSTPDSNTS 723
Query: 604 ----WQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQP 659
E + L+ M++ D++ A+P + A +A+E+F Q D EK +
Sbjct: 724 TSTALNTPENRTLIKRMLIKCADIANPARPRYLCKEWAYRIAEEYFSQTDEEKRRGLPVV 783
Query: 660 IAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKV 718
+ + DR + +P+ QV FID LY D F ++ DN W+ A+++
Sbjct: 784 MPVFDRATCN-VPRSQVWFIDYFVSDLYDAW-DAFAYVPETIRHLTDNYDYWKKAADEL 840
>UniRef50_A4VDP2 Cluster: Cyclic nucleotide phosphodiesterase; n=1;
Tetrahymena thermophila SB210|Rep: Cyclic nucleotide
phosphodiesterase - Tetrahymena thermophila SB210
Length = 1074
Score = 106 bits (255), Expect = 2e-21
Identities = 69/254 (27%), Positives = 125/254 (49%), Gaps = 7/254 (2%)
Query: 445 EKFHIPYDVLCRWILSVKKNY--RPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEIL 502
+++ IP + ++ +++ Y R +HN+ H + V F + ++++ ++
Sbjct: 757 KEYEIPIEEFITFLYKLREKYNKRENPFHNFDHGIMVMHGCFMIGCRTNANKYLNSIQEF 816
Query: 503 GLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQA 561
L+ + LCHD+ HRG NAF+ T S LAI Y S +E HH IL + NIF+
Sbjct: 817 SLVFSGLCHDVSHRGKTNAFEVNTMSKLAIRYHDQSVLEQHHIAHTFKILRQSNANIFKN 876
Query: 562 LSPRDYKDVMHVVETAILSTDLAMYFKK----KSKFLELVDNGEFDWQAQEKKELLCGMM 617
L+ + + + V IL+TD++ +F ++ FL+ V E + +++ LL G +
Sbjct: 877 LTIQKVQQIRRYVINNILATDMSKHFDYLKDFQNDFLQEVHKKESNQFEEKEINLLTGTI 936
Query: 618 MTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVG 677
+ D A+ +E+ + + V EF Q E Q QQ + D +K L + + G
Sbjct: 937 IHTSDFHHTAQKFELSKQWSVKVNKEFSQQYIEEGKQGVQQTSYLKDLDKMHVLAKNEAG 996
Query: 678 FIDTICLPLYKVLS 691
FI I PL++ ++
Sbjct: 997 FIKMIVKPLWETMN 1010
>UniRef50_UPI0000E7FF0E Cluster: PREDICTED: similar to cAMP
phosphodiesterase PDE7, partial; n=1; Gallus gallus|Rep:
PREDICTED: similar to cAMP phosphodiesterase PDE7,
partial - Gallus gallus
Length = 482
Score = 105 bits (253), Expect = 4e-21
Identities = 64/210 (30%), Positives = 107/210 (50%), Gaps = 7/210 (3%)
Query: 470 YHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESP 529
YHN HA +V Q M LK K+ ++ ++L L+A HDLDH G N F KT
Sbjct: 12 YHNAVHAADVTQAMHCYLKEPKLSESLTPWDVLLSLIAAATHDLDHPGVNQPFLIKTNHY 71
Query: 530 LAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFK 588
LA LY +TS +E+HH+ V +L + +F +S + + + + IL+TD++ +
Sbjct: 72 LATLYKNTSVLENHHWRSAVGLL--RESGLFAHMSLENRQLMESQIGDLILATDISQQNE 129
Query: 589 KKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQG 648
S F +D G+ + + + M + D+ + WE+ + ++ V +EFF QG
Sbjct: 130 YLSMFRSHLDRGDLCLEDANHRHFILQMALKCADICNPCRTWELSKQWSEKVTEEFFHQG 189
Query: 649 DLE-KLQLNQQPIAMMDREKKDELPQMQVG 677
D+E K L P+ DR+ + + +Q+G
Sbjct: 190 DIEKKYHLGVSPLC--DRQ-TETIANIQIG 216
Score = 93.9 bits (223), Expect = 2e-17
Identities = 67/267 (25%), Positives = 127/267 (47%), Gaps = 16/267 (5%)
Query: 423 FDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQT 482
++L+ + + + T F Q ++ +K+H+ LC N + N +
Sbjct: 171 WELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTETIANIQ---------IGNRSSV 221
Query: 483 MFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEH 541
F+ + + ++ ++L L+A HDLDH G N F KT LA LY +TS +E+
Sbjct: 222 HFSRFHSECLSESLTPWDVLLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLEN 281
Query: 542 HHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGE 601
HH+ V +L + +F +S + + + + IL+TD++ + S F +D G+
Sbjct: 282 HHWRSAVGLLRE--SGLFAHMSLENRQLMESQIGDLILATDISQQNEYLSMFRSHLDRGD 339
Query: 602 FDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPI 660
+ + + M + D+ + WE+ + ++ V +EFF QGD+E K L P+
Sbjct: 340 LCLEDANHRHFILQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPL 399
Query: 661 AMMDREKKDELPQMQVGFIDTICLPLY 687
DR+ + + +Q+GF+ + PL+
Sbjct: 400 C--DRQ-TETIANIQIGFMTYLVEPLF 423
>UniRef50_A5K0J4 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 1001
Score = 105 bits (253), Expect = 4e-21
Identities = 67/239 (28%), Positives = 113/239 (47%), Gaps = 2/239 (0%)
Query: 454 LCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDL 513
L ++L + Y V YHN HA VA +ML + + ++ L V+ LCHD+
Sbjct: 710 LKNFLLKMHSLYNDVPYHNSLHAAQVAHFSKSMLFLLDINHKIPAIDEFCLHVSSLCHDV 769
Query: 514 DHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMH 572
H G NN F +E+ LA+ Y+ S +E++H L ++ NIF+ +
Sbjct: 770 GHPGLNNYFLINSENNLALTYNDNSVLENYHCSLVFKTLKEKNCNIFENYPYNIFTTCKK 829
Query: 573 VVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEV 632
+ AILSTD+ +F+ S F + + D ++ + +++ A D+ W
Sbjct: 830 NIIRAILSTDMKNHFEYISNFRTSKEFIDLDILTSDQTWQIFSLILKAADIGHATLDWNK 889
Query: 633 QHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLS 691
+ + +EF+ QG LEK LN + D D+L Q+GF+ +C+PL+ L+
Sbjct: 890 HYEWTMKINEEFYLQGLLEK-SLNMPNSFLCDINSIDKLANSQIGFLKHLCIPLFSELN 947
>UniRef50_UPI00006CB6E9 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 699
Score = 105 bits (252), Expect = 5e-21
Identities = 80/320 (25%), Positives = 142/320 (44%), Gaps = 20/320 (6%)
Query: 415 LYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY--RPVKYHN 472
L F+F F ++ R +F + EK+ IP C +I ++ Y R +HN
Sbjct: 249 LDQFKFDIFKADQKEKVRIIWSIFQKRNYFEKYKIPISQFCEFIQEIRLRYNKRGNPFHN 308
Query: 473 WRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAI 532
+ H + V + + + + ++ L+ + LCHD+ H N F+ + S LAI
Sbjct: 309 FDHGITVMHGCYMLCCQTVAQTIIKEINEFALIFSGLCHDVSHTARTNLFEVNSMSKLAI 368
Query: 533 LY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKS 591
Y S +E HH IL + NI L + + +V + IL+TD+ +F
Sbjct: 369 RYHDKSVLEQHHIAVTFKILRKKEANILTQLPLEQVQQIRKIVISNILATDIKQHFDLLK 428
Query: 592 KF-LELVDNG---EFDWQAQEKK------------ELLCGMMMTACDVSAIAKPWEVQHR 635
F L + G + D+Q E++ L+ MM+ A D A+ +E+ +
Sbjct: 429 DFELRFGNKGLKLKNDFQINEQECQSVTTYSDNDLNLITNMMIHAADFHGNAQEFELSKK 488
Query: 636 IAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
+ LV EF Q E + Q + D +K+D L + ++GFI+ I PL+++L+
Sbjct: 489 WSLLVNQEFQAQYKEEAEKNIPQTPYLKDLDKRDILAKSEIGFINAIVKPLWELLNKFLG 548
Query: 696 WMTPLRTGT-ADNRRRWQDL 714
+ T ++N ++W +
Sbjct: 549 DDLQISTNNLSNNIKQWDQI 568
>UniRef50_Q3UEI1-2 Cluster: Isoform 2 of Q3UEI1 ; n=1; Mus
musculus|Rep: Isoform 2 of Q3UEI1 - Mus musculus (Mouse)
Length = 652
Score = 105 bits (251), Expect = 7e-21
Identities = 53/164 (32%), Positives = 94/164 (57%), Gaps = 2/164 (1%)
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYRP-VKYHNWRHALNVAQTMFAMLKTGKMERF 495
+F + +L++ F IP D L ++L+++ +Y V YHN HA +V Q+ +L T +E
Sbjct: 354 VFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAV 413
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSE 554
+DLE+L + AC HD+DH G +N F T S LA++Y+ +S +E+HH +L E
Sbjct: 414 FTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGE 473
Query: 555 SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVD 598
+ +IF+ LS + + +V +L+TD++ + + +V+
Sbjct: 474 NCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVE 517
>UniRef50_Q5C402 Cluster: SJCHGC07495 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07495 protein - Schistosoma
japonicum (Blood fluke)
Length = 215
Score = 105 bits (251), Expect = 7e-21
Identities = 49/103 (47%), Positives = 66/103 (64%)
Query: 346 FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQD 405
FT D +FEAFA+F GLGI N+Q+YE A + AKQKV ++ LSYHATA + +L
Sbjct: 112 FTYSDEFLFEAFALFIGLGISNSQLYEKAIRSAAKQKVIMDVLSYHATAPTSEAKRLATS 171
Query: 406 EIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFH 448
IP+ Y+L F F D L+DEDT +A +RMFL+ ++ H
Sbjct: 172 LIPTMRFYHLDKFSFTDVRLSDEDTLKACIRMFLEMNFMKSIH 214
>UniRef50_A2EAR4 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1209
Score = 104 bits (250), Expect = 9e-21
Identities = 102/436 (23%), Positives = 189/436 (43%), Gaps = 33/436 (7%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----- 345
VA + +NI +VE R ++ A + +L +P+++A+ V+G+A+ INK
Sbjct: 795 VALTGSEINIENVENEKRFKDLWPANIKA--KQMLVIPVLDASGQVVGIAKAINKTTMPR 852
Query: 346 FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQD 405
FT D S+ AF+ F GL + A + +E LS + + +L
Sbjct: 853 FTSEDQSLLRAFSSFAGLAFDRFIARQPA-EFGLTDIPLIETLSPTELTAVVPSDRL--- 908
Query: 406 EIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY 465
+ T + S F + + R + +F + L+ F IP V R+ S+ NY
Sbjct: 909 RVFDPLTGIVGSLNFDVYSYPRNELYRFLIHIFTEMGLLSTFTIPIGVALRFFSSIADNY 968
Query: 466 RPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDH--RGTNNAFQ 523
+ + +H++ +A++ Q F ++ K+ + +E+L VA LCHDL H R T NA
Sbjct: 969 QQLPFHDFANAVSTTQFAFWLMMLNKLYIQFTKIELLSFFVAALCHDLGHSDRITVNA-- 1026
Query: 524 TKTESPLAILYSTSTM-EHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTD 582
+ ++ L +LY + E H + +L + NI + L D + +LS D
Sbjct: 1027 -QVQAALDVLYKDQPVNETFHCAALIYLLAQPTCNILENLDSGYVNDFWTLCIDLMLSLD 1085
Query: 583 LAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVAD 642
+ + K + ++ G FD++ + K LL +M+ + + + +P
Sbjct: 1086 PSQHAKLIEEMDIRLNRGPFDFKDKAAKALLLKLMLKSAVTAEVFRP------------- 1132
Query: 643 EFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRT 702
FD +N+ + ++K L +M +++ PL +VL T + PL
Sbjct: 1133 --FDPTKPWTTSVNKLSVVASKGDQKVLLEEM-TKYLNETSTPLVRVLLRTMTNVQPLSD 1189
Query: 703 GTADNRRRWQDLAEKV 718
N W++ +K+
Sbjct: 1190 QLKLNMNGWKEQLDKL 1205
Score = 68.1 bits (159), Expect = 9e-10
Identities = 33/86 (38%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Query: 146 GSKEFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECL 205
G+ EFS DVE+ + FCGI + NAQL+E++ K+ +L +A S+ + LE L
Sbjct: 685 GAVEFSRTDVELMTAFNVFCGIALSNAQLYEAATKSKKKMTAMLDIALSL-STSTTLEEL 743
Query: 206 VTKIMTEARDLLKCERCAVFILDTDH 231
+T I++ AR+L++ E C +F +D H
Sbjct: 744 ITSIISRARELIEAEHCFLFAVDRLH 769
Score = 64.9 bits (151), Expect = 9e-09
Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 10/120 (8%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLIN 344
IA VA++ +++NI D R N + + S G RT +LC+PI +++ +IG Q+IN
Sbjct: 625 IAGHVAKTGETINIPDAYNDPRFN--PSVDKSTGYRTKSILCVPIKSSSGIIIGCTQMIN 682
Query: 345 K-----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE-CLSYHATASAED 398
K F+ DV + AF +FCG+ + N Q+YE A K K L+ LS + + E+
Sbjct: 683 KLGAVEFSRTDVELMTAFNVFCGIALSNAQLYEAATKSKKKMTAMLDIALSLSTSTTLEE 742
Score = 45.6 bits (103), Expect = 0.006
Identities = 18/38 (47%), Positives = 27/38 (71%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
+FN +D TGY+T+ ILC+PI + G ++G Q+INK
Sbjct: 646 RFNPSVDKSTGYRTKSILCVPIKSSSGIIIGCTQMINK 683
>UniRef50_A0CB76 Cluster: Chromosome undetermined scaffold_163,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_163,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 619
Score = 104 bits (250), Expect = 9e-21
Identities = 71/253 (28%), Positives = 121/253 (47%), Gaps = 11/253 (4%)
Query: 470 YHNWRHALNVAQTMFAMLKTGKMERF--MSDLEILGLLVACLCHDLDHRGTNNAFQTKTE 527
YHN HA +V T++ ++ + ++ ++ LL++ HD DH G NN F + T
Sbjct: 366 YHNVIHAFDVTHTVYFFIQKCNFKEIGKLTKIDYSILLMSAAAHDADHPGLNNIFLSNTR 425
Query: 528 SPLAILYST-STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMY 586
LA+ Y+ S +E HH + ++ + +D+K ILSTD AM+
Sbjct: 426 HDLAMTYNDKSPLEQHH--AATLFRYIRETDLLVHFTLQDFKYFREKSINMILSTDNAMH 483
Query: 587 FKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFD 646
K +K + + +FD + K + ++ A D+S KP + + V EF+
Sbjct: 484 GKDYNKLKARLASNDFD-PGSKDKGICFDTLLHAADISNPFKPMKNYEQWTFRVLGEFWH 542
Query: 647 QGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTAD 706
QGD EK +L P+ M+ + + + Q+GFID + LP Y LS P ++ +
Sbjct: 543 QGDREK-ELGL-PVTMLCDRRTTNVAKSQIGFIDFMVLPYYNTLSQILPQLSEFIEQITE 600
Query: 707 NRRRWQDLAEKVD 719
N++ W AEK++
Sbjct: 601 NKKAW---AEKIE 610
>UniRef50_A0DF61 Cluster: Chromosome undetermined scaffold_49, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_49,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 768
Score = 103 bits (248), Expect = 2e-20
Identities = 72/277 (25%), Positives = 134/277 (48%), Gaps = 10/277 (3%)
Query: 418 FQFHDFDLTDEDT-CRATLRMFLQCELVEKFHIP-YDVLCRWILSVKKNYRPVKYHNWRH 475
F ++ DL+ ++ +F ++++ I + L + + ++ Y+ YHN H
Sbjct: 440 FTLNNLDLSQRMIFIEGSINLFKIFKVIQTLKITNLETLGEFSVKIESLYQNNFYHNSMH 499
Query: 476 ALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS 535
A++VA + L+ G + + D + LL++ L HD+ H G NN F T LA+L++
Sbjct: 500 AIDVANSTAFFLQNG-LSTLIDDFQATCLLISSLAHDIGHPGLNNGFMTANRCRLALLFN 558
Query: 536 -TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFL 594
S +E++H +L + NI + LS + K IL TDL +F+ +KF
Sbjct: 559 DQSVLENYHSFLLFQVLTQSNCNIIENLSINEIKGFRKYCLNLILDTDLTRHFQLMNKFQ 618
Query: 595 ELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQ 654
++ E ++L+ + + DV AK ++ ++ + +EFF QGDLE
Sbjct: 619 NYLNVNE---SPAVDQQLIMSIGIKCADVGHGAKELKLHKLWSRRIVEEFFLQGDLENYL 675
Query: 655 LNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLS 691
+ PI+ M ++ + + Q GF+ I LP+++ S
Sbjct: 676 --KVPISPM-CDRNQNVSKSQEGFLKAIVLPMFEAFS 709
>UniRef50_A6S8A0 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 945
Score = 103 bits (247), Expect = 2e-20
Identities = 88/337 (26%), Positives = 160/337 (47%), Gaps = 43/337 (12%)
Query: 410 AETYNLYSFQFHDFDLTDEDTCRATLRMF---LQCELVEKFHIPYDVLCRWILSVKKNYR 466
A + + F HDF+ D++ A+ MF L +EK+ I + L ++++ ++ Y
Sbjct: 316 ARAISSWHFSAHDFE--DDELLYASSLMFQHALSVPELEKWRISTENLTAFLITSREAYN 373
Query: 467 P-VKYHNWRHALNVAQTMFAML-------------------KTGKMERFMSDLEILGLLV 506
V YHN+RH ++V Q +F L K+ + + + L L++
Sbjct: 374 SFVPYHNFRHVVDVLQAIFHFLVRLGSLPEYPPSPDGTTSQKSSPIAELIRPFDALTLMI 433
Query: 507 ACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPR 565
+ HD+ H G NNAF +PLA LY+ S +E H IL L+
Sbjct: 434 TAIGHDVGHPGVNNAFLVHLNAPLAQLYNDRSVLESFHCAAYSQILRR------HWLAAF 487
Query: 566 DYKDVMHVVETAILSTDLAMYF--KKKSKFLE--LVDNGEF--DWQA---QEKKELLCGM 616
+ +D+ H++ + IL+TD+ ++F KK +L+ L +NG W ++++ L C +
Sbjct: 488 EERDMRHLMISTILATDMGLHFDYMKKLGYLQEKLHENGGVTDGWNGRTIEDQRTLACSL 547
Query: 617 MMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEK-LQLNQQPIAMMDREKKDELPQMQ 675
++ D+S +A+ ++ R +++ DEF Q +E+ L + A RE EL + Q
Sbjct: 548 LIKCADISNVARKFDTATRWTEILTDEFARQASMEQDLGIPTALYAAPVRE-VIELGKSQ 606
Query: 676 VGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
+GF++ +PL+ ++D P M N+ W+
Sbjct: 607 IGFMNMFAIPLFGGVTDVMPGMAFCVEELERNKAAWE 643
>UniRef50_Q4SPD6 Cluster: Chromosome 16 SCAF14537, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 16 SCAF14537, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 560
Score = 103 bits (246), Expect = 3e-20
Identities = 93/345 (26%), Positives = 166/345 (48%), Gaps = 59/345 (17%)
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAM-----LKTGK 491
M+ LV++F++ L RW+L++++NYR +HN+RH V+Q M+ M L+ G
Sbjct: 219 MYHDLGLVKEFNMNPITLKRWLLAIQENYRNNPFHNFRHCFCVSQMMYGMIHLCNLQVGS 278
Query: 492 M-----ERFMSDLEI--------------LGLLV-ACLCHDLDHRGTNNAFQTKTESPLA 531
M F++D ++ +G+L+ A +CHDLDH G NN +Q + LA
Sbjct: 279 MLLTIMMLFITDPQVNPGDRDQEKLTLTDMGILMTAAVCHDLDHPGYNNTYQINARTELA 338
Query: 532 ILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHV-----VETAILSTD--L 583
+ Y+ S +E+HH IL+ NIF + +K + V +L T+ L
Sbjct: 339 VRYNDISPLENHHCAVAFQILSLPECNIFANVDLEAFKQIRQVNGAKQNHLLVLQTEGKL 398
Query: 584 AMYFKKKSKF---------LELVDNGE-----------FDWQAQEKKELLCGMMMTACDV 623
++ S F ++ +GE FD+ +E L +++ CD+
Sbjct: 399 NVWSNLTSCFQGIITLILATDMARHGEILDSFKQKVDNFDFTNEEHVTCLKMVLIKCCDI 458
Query: 624 SAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIA-MMDREKKDELPQMQVGFIDTI 682
S +P EV + +E+F Q D EK + P+A MDR+K + P Q+GFI +
Sbjct: 459 SNEVRPTEVAEPWVDCLLEEYFMQSDREKSE--GLPVAPFMDRDKVTK-PTAQIGFIKFV 515
Query: 683 CLPLYKVLSDTFPWMTPLRT-GTADNRRRWQDLAEKVDMGLTWID 726
+P+++ + FP + + D+R +++L +++D +T ++
Sbjct: 516 LIPMFETVMKLFPQIEEIMVQPLRDSRDHYEEL-KQIDDAMTEVE 559
>UniRef50_Q01C40 Cluster: Cyclic GMP phosphodiesterase; n=1;
Ostreococcus tauri|Rep: Cyclic GMP phosphodiesterase -
Ostreococcus tauri
Length = 674
Score = 103 bits (246), Expect = 3e-20
Identities = 66/194 (34%), Positives = 100/194 (51%), Gaps = 6/194 (3%)
Query: 409 SAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPV 468
S + L S+ F F+++D +C +RMF + + E P+ L R++ V+ YR
Sbjct: 253 SVDIVALNSWSFDVFEVSDSISC--IMRMFHELNMFELVD-PFK-LRRFLSEVESMYRDN 308
Query: 469 KYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTES 528
YH ++HA +VA T + + K + MS LEI LLVA L HDLDH G NA+ T
Sbjct: 309 PYHCFKHAFDVAHTTYLYILAVKDQVEMSQLEIFSLLVAALVHDLDHPGVTNAYLIATRD 368
Query: 529 PLAILYS-TSTMEHHHFDQ-CVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMY 586
+A+ Y+ S +E+ H + + N+E NI A Y V + +L TD+A +
Sbjct: 369 SIAMTYNDESVLENLHLSRFFTLCQNNEDANILSAFDEDTYSVVRRTIIGCVLHTDMAHH 428
Query: 587 FKKKSKFLELVDNG 600
FK S+ E+V G
Sbjct: 429 FKLVSRMNEMVSLG 442
Score = 62.5 bits (145), Expect = 5e-08
Identities = 38/123 (30%), Positives = 65/123 (52%), Gaps = 2/123 (1%)
Query: 604 WQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMM 663
++ E+++L+ +++ D+S KP E+ + A V +EFF+QGD E+ + MM
Sbjct: 478 FKTDEERQLMLNVLLHCADISNAVKPNELCVKWASRVLEEFFNQGDRERAK-GMSVSPMM 536
Query: 664 DREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKVDMGLT 723
DRE + Q+ FI+ + PLY + FP ++ L +NRR +Q+ E+ T
Sbjct: 537 DRE-TTSVGLSQINFIEFVIAPLYVQFAAIFPAVSHLLDRLIENRRYYQETYERELAEST 595
Query: 724 WID 726
ID
Sbjct: 596 EID 598
>UniRef50_A0D565 Cluster: Chromosome undetermined scaffold_38, whole
genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_38,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 964
Score = 102 bits (244), Expect = 5e-20
Identities = 71/256 (27%), Positives = 126/256 (49%), Gaps = 12/256 (4%)
Query: 444 VEKFHIPYDVLCRWI--LSVKKNYRPVKYHNWRHALNVAQTMFAM----LKTGKMERFMS 497
+E + I D LC ++ L K N R ++HN+ H + V Q A+ +KT + ++
Sbjct: 686 IEDYRISQDALCSFLCALEYKYNKRGNQFHNYDHGVTVMQCTHAISLEIMKT-QYAHLLN 744
Query: 498 DLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESN 556
L+++ LCHD+ H G N F+ + S L I Y S +E HH + +L + S
Sbjct: 745 QFTKFVLILSGLCHDVSHTGRTNIFEINSLSNLTIRYHDRSVLEQHHAATSIKLLCAPST 804
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGM 616
NI + +++D + + IL TD+ +F F + E ++ ++ +L+ GM
Sbjct: 805 NIIPNFTSVEFRDFRKLFISNILYTDITEHFNLIKNFEARIK--ELNFGTEDDIKLMTGM 862
Query: 617 MMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELPQMQ 675
++ D + AKP+ + + V EF +Q +LE K Q P M D +++ + + +
Sbjct: 863 IIHTSDFTGGAKPFNLSREWSTRVNMEFQEQYNLEGKFGYPQLPY-MKDLDQQPIMAKSE 921
Query: 676 VGFIDTICLPLYKVLS 691
VGF I PL+ ++S
Sbjct: 922 VGFFKFIVRPLWSIMS 937
>UniRef50_A5JZK3 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=7; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 783
Score = 101 bits (242), Expect = 8e-20
Identities = 68/255 (26%), Positives = 125/255 (49%), Gaps = 9/255 (3%)
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMER 494
+ + +C V + ++P + L + +K+ Y V YHN HA VA+ ++
Sbjct: 466 MSLLTKCYTVNR-NVPNETLRSLLCEMKEGYNNVPYHNCIHAAMVAEQCNILVNNLDTAN 524
Query: 495 FMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNS 553
+ D E+ L+A L HD+ H G N F + + L+++Y+ S +E++H IL
Sbjct: 525 ILRDNEMAAFLLAALGHDIGHFGRTNLFLKNSSNFLSVIYNDKSILENYHCSYLFHILFK 584
Query: 554 ESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF-LELVDNGEFDWQAQEKKEL 612
E NNIF+ S + ++ + IL+TD++ + K ++F ++ + + EK +
Sbjct: 585 EQNNIFKNESAKTVLNLRQEIIQVILATDMSKHIKILAQFRIKSIKIRSY----IEKNII 640
Query: 613 LC-GMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDEL 671
LC M++ A D+S W + K + +EF+ +GD E+L+ Q + DR D
Sbjct: 641 LCLKMIIKAADLSHNCVDWSEHYLWVKRLVNEFYYEGD-EQLEKGYQINPLFDRNSHDNF 699
Query: 672 PQMQVGFIDTICLPL 686
++Q F+ + PL
Sbjct: 700 IKIQRTFLKELVFPL 714
>UniRef50_A0EBQ7 Cluster: Chromosome undetermined scaffold_88, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_88,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 744
Score = 101 bits (242), Expect = 8e-20
Identities = 68/233 (29%), Positives = 112/233 (48%), Gaps = 7/233 (3%)
Query: 461 VKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNN 520
++ Y YHN HA++VA + L+ G +E ++ E L+++ L HD+ H G NN
Sbjct: 456 IESFYMQNPYHNSIHAMDVANSASFFLENG-LE--VTPFEQCCLIISALSHDVGHPGLNN 512
Query: 521 AFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAIL 579
F ++S A++Y+ S +E +H +L E NI + ++ DYK IL
Sbjct: 513 GFLVASQSKQALIYNDQSVLESYHASLMFHVLKDEKANILKNINDVDYKGFRKYCLNLIL 572
Query: 580 STDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKL 639
TDL +F +KF + G ++ K L+ + + DV AK + ++
Sbjct: 573 DTDLQKHFPLLNKFKNFLALGSDSQSDEQTKLLILSIAIKCADVGHGAKQLNLHKIWSRR 632
Query: 640 VADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSD 692
+ +EFF QGDLE Q+ Q M DR + + + Q GF+ I PL+ +
Sbjct: 633 IIEEFFLQGDLE-AQVGIQVTPMCDRSQ--SVTKSQEGFLKAIVWPLFDAFGE 682
>UniRef50_A1D4A4 Cluster: High affinity cAMP phosphodiesterase,
putative; n=8; Trichocomaceae|Rep: High affinity cAMP
phosphodiesterase, putative - Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 1009
Score = 101 bits (242), Expect = 8e-20
Identities = 78/292 (26%), Positives = 145/292 (49%), Gaps = 40/292 (13%)
Query: 457 WILSVKKNYRP-VKYHNWRHALNVAQTMFAML-----------------KTGKMERFMSD 498
++L+ + +Y V YHN+RHA++V Q++F L + ++
Sbjct: 349 FLLACRASYNSFVLYHNFRHAIDVLQSVFCFLVHIGALPPYGSVGTSPDSPSSIASLLTP 408
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNN 557
+ L LL++ + HD+ H G NN F K +PLA LY+ S +E H C +
Sbjct: 409 FDTLTLLISAIGHDVGHPGVNNFFLVKLNAPLAQLYNDNSVLEAFH---CAAF-----SQ 460
Query: 558 IFQALSPRDYKD--VMHVVETAILSTDLAMYFKKKSKFLELVD----NGEF--DWQAQE- 608
I + P +KD + ++ ++IL+TD+ ++ K + L + NG+ W+ Q+
Sbjct: 461 ILRRHWPAAFKDRQLRKLLISSILATDMGVHQKFMERLGSLQEKFYANGKSVDGWKPQDI 520
Query: 609 --KKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDRE 666
K L+CG+++ D+S +A+PW++ + K++ +EF +QG++E+ + + E
Sbjct: 521 EIYKTLVCGLLIKCADISNVARPWDIAEKWTKILQEEFANQGEMEREVGMETALFGGPPE 580
Query: 667 KKD--ELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAE 716
+ +L Q+GF+ LPL++ +SD P + N+ RW LA+
Sbjct: 581 LGNVYKLATGQIGFMSIFALPLFEGVSDLLPELRFTVEHIRTNQTRWHFLAD 632
>UniRef50_A3FQ29 Cluster: CGMP phosphodiesterase A4; n=2;
Cryptosporidium|Rep: CGMP phosphodiesterase A4 -
Cryptosporidium parvum Iowa II
Length = 997
Score = 100 bits (239), Expect = 2e-19
Identities = 78/272 (28%), Positives = 123/272 (45%), Gaps = 18/272 (6%)
Query: 469 KYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTES 528
KYHN H NV + + + + +E L ++A L HD+ H G + F +
Sbjct: 723 KYHNELHGTNVCHLAICLSRATGLWSHLDTVERLASVIASLGHDVGHIGRTSNFLVNSRH 782
Query: 529 PLAILYS-TSTMEHHHFDQCVMIL---NSESNNIFQALSPRDYKDVMHVVETAILSTDLA 584
LAI Y+ S +E H I+ + + Q+ +K+ +V IL TD+
Sbjct: 783 MLAINYNDRSVLEMFHASLTFRIIYYYGGGAADFLQSWDAELHKEFRRIVIELILETDMH 842
Query: 585 MYFKKKSKFLELVDNGEFDWQA---QEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVA 641
+F+ S+F V DW + + +L + A D+ A W ++ + V
Sbjct: 843 RHFECVSRF--RVRRQAVDWDPYGDAQDRLMLARTCLKAADIGHGALKWNQHYKWCRSVV 900
Query: 642 DEFFDQGDLEK-LQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLS--DTFPWMT 698
+EFF QGD EK L L PI DRE D +P+ QVGF++ +CLPL++ L D +
Sbjct: 901 EEFFLQGDEEKALSLPISPIC--DRESTD-VPKSQVGFLNFVCLPLFQELCYVDVEGDVR 957
Query: 699 PLRTGTADNRRRWQDLAEKVDMGLTWIDHDTI 730
+N W+D+AE G+ W D +
Sbjct: 958 RCIDRILENINNWEDIAE---AGIQWDSEDAL 986
>UniRef50_O95263 Cluster: High affinity cAMP-specific and
IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B;
n=83; Euteleostomi|Rep: High affinity cAMP-specific and
IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B -
Homo sapiens (Human)
Length = 885
Score = 100 bits (239), Expect = 2e-19
Identities = 74/296 (25%), Positives = 135/296 (45%), Gaps = 18/296 (6%)
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKME 493
L++F + + E + L W ++ NY YHN HA +V L +++
Sbjct: 578 LKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVK 637
Query: 494 RFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILN 552
+ L+ + L+A HD+DH G N+F S LA+LY+ T+ +E HH +
Sbjct: 638 GSLDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTV 697
Query: 553 SESN-NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDN---GEFDWQAQE 608
++ NIF+ + Y+ + + +L+T++ +F+ +KF+ ++ E + E
Sbjct: 698 KDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCE 757
Query: 609 ---------KKELLCGMMMTAC-DVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQ 658
+ ++L MM C DV+ +P ++ A +++E+F Q D EK Q
Sbjct: 758 CNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPV 817
Query: 659 PIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDL 714
+ + DR +P+ Q+ FID ++ D F + L ADN + W+ L
Sbjct: 818 VMPVFDR-NTCSIPKSQISFIDYFITDMFDAW-DAFAHLPALMQHLADNYKHWKTL 871
>UniRef50_Q8CFW8 Cluster: Phosphodiesterase 8B; n=13;
Euteleostomi|Rep: Phosphodiesterase 8B - Mus musculus
(Mouse)
Length = 730
Score = 99 bits (238), Expect = 2e-19
Identities = 73/296 (24%), Positives = 136/296 (45%), Gaps = 18/296 (6%)
Query: 435 LRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKME 493
L++F + + E + L W+ ++ NY YHN HA +V L +++
Sbjct: 423 LKVFSRFGVCEFLNCTETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVK 482
Query: 494 RFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILN 552
+ L+ + L+A HD+DH G N+F S LA+LY+ T+ +E HH +
Sbjct: 483 GSLDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALVFQLTV 542
Query: 553 SESN-NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELV------DNGEFDWQ 605
++ NIF+ + Y+ + + +L+T++ +F+ +KF+ + ++ D +
Sbjct: 543 KDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAESEGSDCE 602
Query: 606 AQ-------EKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQ 658
E + L+ MM+ DV+ +P ++ A +++E+F Q D EK Q
Sbjct: 603 CNPTGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPV 662
Query: 659 PIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDL 714
+ + DR +P+ Q+ FID ++ D F + L ADN + W+ L
Sbjct: 663 VMPVFDR-NTCSIPKSQISFIDYFITDMFDAW-DAFAHLPALMQHLADNYKHWKTL 716
>UniRef50_A0CZB5 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_32, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1270
Score = 99 bits (238), Expect = 2e-19
Identities = 64/241 (26%), Positives = 116/241 (48%), Gaps = 5/241 (2%)
Query: 458 ILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRG 517
+L K N + +HN+ H ++V Q+ ML+ K ++F+ D + +++ LCHD+ H G
Sbjct: 995 VLQQKYNKKNNSFHNYDHGISVMQSAHFMLQCEKAKQFIDDFRRMATIISGLCHDVSHTG 1054
Query: 518 TNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVET 576
N F ++S LA Y +S +E HH + +L S N L+ ++ ++
Sbjct: 1055 RTNVFMINSQSKLATRYHDSSPLEQHHAATTIFMLKDSSLNFLSNLTKEQHQQFRRILID 1114
Query: 577 AILSTDLAMYFKKKSKFLELV--DNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQH 634
IL TD+ ++F F + D + + +LL GM++ D + AK +++
Sbjct: 1115 NILYTDIKVHFTLLKDFESRIKDDVTKPFGTGDDDLKLLTGMIIHTADFNGGAKVFDISR 1174
Query: 635 RIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDT 693
++ V EF Q + E +L + Q P + D K + + ++GF I PL+ L+
Sbjct: 1175 IWSERVNKEFSAQYEEEGRLGIPQTPF-LKDLHKIHIMAKSEMGFFKVIVRPLWFTLNAF 1233
Query: 694 F 694
F
Sbjct: 1234 F 1234
>UniRef50_UPI0000E46CDB Cluster: PREDICTED: similar to
phosphodiesterase 9A; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to phosphodiesterase
9A - Strongylocentrotus purpuratus
Length = 526
Score = 99.1 bits (236), Expect = 4e-19
Identities = 64/185 (34%), Positives = 98/185 (52%), Gaps = 7/185 (3%)
Query: 513 LDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVM 571
LD G NNA+ + LA+ Y+ S +E+HH IL NIF+ LSP +K V
Sbjct: 238 LDRPGYNNAYHVNAGTELALRYNDISPLENHHCSVAFKILEKPHCNIFKNLSPEIFKQVR 297
Query: 572 HVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWE 631
+ IL+TD+A + + + F +++ FD+ + K+LL + + D+S A+P +
Sbjct: 298 EGIIRCILATDMAKHNEILNGFKDIIST--FDFSNKVHKDLLTKICIKVADISNEARPMD 355
Query: 632 VQHRIAKLVADEFFDQGDLEKLQLNQQPIA-MMDREKKDELPQMQVGFIDTICLPLYKVL 690
V + EFF+Q D+EKL+ P+A MDREK + Q GFI + LPL++ L
Sbjct: 356 VAEPWIDCLLQEFFNQSDMEKLE--GLPVAPFMDREKVTK-HTSQTGFIRFVLLPLFESL 412
Query: 691 SDTFP 695
FP
Sbjct: 413 GLLFP 417
>UniRef50_Q8I0P7 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-3; n=4; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-3 - Caenorhabditis elegans
Length = 578
Score = 99.1 bits (236), Expect = 4e-19
Identities = 93/355 (26%), Positives = 155/355 (43%), Gaps = 43/355 (12%)
Query: 398 DTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTC--RATLRMFLQCELVEKFHIPYDVLC 455
DT +L D P ++SF T R T +F Q EL F +
Sbjct: 183 DTRELDTD--PDLAETAVWSFPIFQMSRKHPQTILSRLTYNIFQQAELFRIFKVSPIKFF 240
Query: 456 RWILSVKKNYRPVKYHNWRHALNV-----------AQTMFAMLKT--------------G 490
+ +++K Y + YHN HA +V ++ F KT
Sbjct: 241 NFFHALEKGYWEIPYHNRIHAADVLHGCYYLSAHPVRSTFLTPKTPDSVLTPPHPHHQHS 300
Query: 491 KMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVM 549
+ +S LE++ L A HD DH G NAF + E AILY+ S +E+HH +
Sbjct: 301 SIMSQLSTLELMALFTAAAMHDYDHPGRTNAFLVQVEDKKAILYNDRSVLENHHAAESWK 360
Query: 550 ILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEK 609
+LN N+ + L P + K ++V IL+TDL +F+ F E + E D Q +
Sbjct: 361 LLNKPENHFIENLDPAEMKRFRYLVLEYILATDLKQHFEIIMTFTERLT--EIDVQVETD 418
Query: 610 KELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIA-MMDREKK 668
+ L+ +++ D+++ KP+ + + + +EF++QGD E+ + PI MDR
Sbjct: 419 RLLIGKLLIKMADINSPTKPYGLHRQWTDRICEEFYEQGDDERRR--GLPITPYMDRGDA 476
Query: 669 DELPQMQVGFIDTICLPLYKVLSD--TFPWMTPLRT-----GTADNRRRWQDLAE 716
++ ++Q FI + PL +++ P + L T N R+W++ E
Sbjct: 477 -QVAKLQDSFIAHVVSPLATAMNECGLLPILPGLDTSELIINMEHNHRKWKEQIE 530
>UniRef50_A0D3N1 Cluster: Chromosome undetermined scaffold_36, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_36,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 429
Score = 98.3 bits (234), Expect = 8e-19
Identities = 75/332 (22%), Positives = 155/332 (46%), Gaps = 22/332 (6%)
Query: 406 EIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY 465
+I + + +L + F+ T + +A++ +F E VE+F Y+ L + + NY
Sbjct: 99 KIATLKYEDLINVNFNHHHYTSREMLKASMMIFQHLE-VEQF-ANYNNLENLLTHINLNY 156
Query: 466 RPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTK 525
V YHN+ HA + Q +F + + ++ F+S +I L+A L HD++H+G NN ++ K
Sbjct: 157 NIVSYHNFTHAFALFQLLFCVYEKSDLKLFVSKQDIFAALLASLSHDINHKGVNNLYKVK 216
Query: 526 TESPL-AILYSTSTMEHHHFDQCVMIL-NSESNNIFQALSPRDYKDVMHVVETAILSTDL 583
L + + +E H IL ++ N L ++ ++ ++IL+TD+
Sbjct: 217 KSKKLNKNICEQAVLESMHVSTLFNILAQNQQLNFLNYLPNAQQQEFKRILVSSILATDM 276
Query: 584 AMYFKKKSKF-------LELVDNGE----------FDWQAQEKKELLCGMMMTACDVSAI 626
+F S F +EL ++ + F+ + + ++ + +++ ACD+S
Sbjct: 277 GQHFNIFSCFKDRVNATIELRESQDITDPLIRYRGFNKENFDDRKFILNVLVHACDISNP 336
Query: 627 AKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPL 686
W+ + + L+A EF DQ +++ + AM+ + K Q F++T LP
Sbjct: 337 CLEWDAYMKWSFLLAQEFQDQ-TIKEAAKGLEVTAMLQYKDKLTFFNGQTFFLNTFVLPQ 395
Query: 687 YKVLSDTFPWMTPLRTGTADNRRRWQDLAEKV 718
++ ++ +P + L N ++ +K+
Sbjct: 396 WQTIATLYPSLIELPNEVKRNLEILEEEKKKI 427
>UniRef50_Q2H9G5 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 894
Score = 97.9 bits (233), Expect = 1e-18
Identities = 89/327 (27%), Positives = 148/327 (45%), Gaps = 43/327 (13%)
Query: 404 QDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMF---LQCELVEKFHIPYDVLCRWILS 460
Q E+ SA + F HDF T+++ A L MF L +E + IP D L R++L+
Sbjct: 275 QAEVTSA--VGQWHFCAHDF--TEDELVVAALVMFKHALSMPELEPWRIPTDRLHRFLLA 330
Query: 461 VKKNYRP-VKYHNWRHALNVAQTMFAML-KTGKMERFMS-------------------DL 499
+ Y V YHN+RH ++V Q F L + G + + S
Sbjct: 331 CRAAYNTFVPYHNFRHVVDVLQATFHFLVRIGALPPYRSADGLLSAACRKSPIAELLRPF 390
Query: 500 EILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNI 558
E L LL+ + HD+ H G NN F +PLA LY+ S +E H IL
Sbjct: 391 EALTLLITAIGHDVGHPGVNNGFLVTLNAPLAQLYNDRSVLESFHCAAYSQILRRYWPET 450
Query: 559 FQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELV-----DNGEFDWQA---QEKK 610
F D + H++ ++IL+TD+ ++F K +L +N DW E+K
Sbjct: 451 F------DDSKMRHLMISSILATDMGLHFDYMRKLGDLQGKLRPNNSTEDWDEGVKNEQK 504
Query: 611 ELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDE 670
L C +++ D+S + + + + K++++EF Q +E + + ++ K
Sbjct: 505 ALTCALLIKCADISNVTRRHDAAIQWMKILSEEFSRQATMENELEIKTSLMSEPKQDKLS 564
Query: 671 LPQMQVGFIDTICLPLYKVLSDTFPWM 697
L Q+ F++ LPL++ ++D P M
Sbjct: 565 LTTSQLKFMNLFALPLFQGVADILPAM 591
>UniRef50_A0CU34 Cluster: Chromosome undetermined scaffold_28, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_28,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 903
Score = 97.5 bits (232), Expect = 1e-18
Identities = 63/238 (26%), Positives = 114/238 (47%), Gaps = 6/238 (2%)
Query: 459 LSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGT 518
L K N +HN+ H +NV F K +D + + +A LCHD+ H GT
Sbjct: 636 LKYKYNKTANPFHNFTHGVNVMHGCFLFTHHPKFGFCFNDQQRFAMTLAGLCHDVGHPGT 695
Query: 519 NNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETA 577
NN FQ T++ LA+LY+ S +E+HH +L E + +++ D + +
Sbjct: 696 NNLFQVNTQTKLALLYNDKSVLENHHIAVTYKLLALEQCDFLESVPRADKLMIRKYIVNN 755
Query: 578 ILSTDLAMYFK----KKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQ 633
+L+TD +FK + KF + + + +++ + K LL G + A D AK ++V
Sbjct: 756 VLATDNQFHFKILNDIEIKFAQSQGDPKI-FESDDNKLLLSGFLTHAADFFGAAKSYQVA 814
Query: 634 HRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLS 691
++ + EF Q LE + Q + + + + + + ++GF+ I P+Y+ L+
Sbjct: 815 RTWSERLRREFQAQSQLEDIVGIAQTPYLRNLDDEVQYAKNEIGFLKVIVKPIYESLN 872
>UniRef50_Q4RR95 Cluster: Chromosome 14 SCAF15003, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 14 SCAF15003, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 456
Score = 96.7 bits (230), Expect = 2e-18
Identities = 90/330 (27%), Positives = 141/330 (42%), Gaps = 37/330 (11%)
Query: 416 YSFQFHDFDLTDEDTCRATL--RMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHN 472
++F FD TL +F LV F + L R++ V+++Y YHN
Sbjct: 132 WNFDIFLFDRLTNGNSLVTLMCHLFNVYGLVHHFQLDMVKLHRFLGMVQEDYHSQNPYHN 191
Query: 473 WRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAI 532
HA +V Q M+ LK K+ +S L++ L+A HD+DH G N F KT LA
Sbjct: 192 AVHAADVTQAMYCYLKEPKLAEQLSPLDVFLGLMAAAAHDVDHPGVNQPFLIKTRHHLAS 251
Query: 533 LY-------STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAM 585
LY +TS +E HH+ V +L + + L +D+ + + IL+TD++
Sbjct: 252 LYQVHQSVQNTSVLESHHWRSTVGML--RESGLLSHLPADMSQDIEQQLGSLILATDISR 309
Query: 586 YFKKKSKFLELVDNGEFDWQAQEKKELL----------------CGMMMTAC-DVSAIAK 628
+ F E +D+ + D Q + + C + C DV +
Sbjct: 310 QNEFLLTFGEHLDHQDLDLQLPSHRHFILQHAFRRSVPAVTACVCQQIALKCADVCNPCR 369
Query: 629 PWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLY 687
W + + ++ V +EFF QGDLE K L P+ R + P +Q GFI I PL+
Sbjct: 370 VWALSRQWSERVCEEFFRQGDLERKFDLEISPLCDSRRLR----PAIQTGFISYIVEPLF 425
Query: 688 KV---LSDTFPWMTPLRTGTADNRRRWQDL 714
++ P + N+ RW L
Sbjct: 426 DEWHRFTEPSPLSRTMMGHLHQNKARWSRL 455
>UniRef50_Q2V2M6 Cluster: CGMP-specific phosphodiesterase; n=3;
Plasmodium|Rep: CGMP-specific phosphodiesterase -
Plasmodium falciparum
Length = 884
Score = 95.9 bits (228), Expect = 4e-18
Identities = 64/239 (26%), Positives = 113/239 (47%), Gaps = 2/239 (0%)
Query: 454 LCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDL 513
L +++ + Y + YH HA VA +ML M +S ++ L ++ LCHD
Sbjct: 593 LKKFLFRICSYYNDIPYHTSLHAAQVAHFSKSMLFMLDMNHKISAIDEFCLHISSLCHDT 652
Query: 514 DHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMH 572
H G NN F +E+ LA+ Y+ S +E++H L + + NIF+ +
Sbjct: 653 GHPGLNNYFLINSENNLALTYNDNSVLENYHCSLLFKTLKNPNYNIFEHYPYHIFISCKK 712
Query: 573 VVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEV 632
+ AILSTD+ +F+ S F + ++D + ++ + +++ A D+ W
Sbjct: 713 NIIKAILSTDMKNHFEYISDFRTSKEFIDYDNLSNDQIWQIFCLILKASDIGHSTLEWNK 772
Query: 633 QHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLS 691
+ +EF+ QG LEK LN Q + D ++L Q+ F+ +C+PL+ L+
Sbjct: 773 HLEWTLKINEEFYLQGLLEK-SLNIQNSFLCDINTMNKLALSQIDFLKHLCIPLFNELN 830
>UniRef50_UPI000065D378 Cluster: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).;
n=4; Euteleostomi|Rep: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46). -
Takifugu rubripes
Length = 715
Score = 95.5 bits (227), Expect = 5e-18
Identities = 51/158 (32%), Positives = 88/158 (55%), Gaps = 3/158 (1%)
Query: 420 FHDFDLTDEDTCRATL-RMFLQCELVEKFHIPYDVLCRWILSVKKNYRP-VKYHNWRHAL 477
FH +L++ + +F + +L++ F IP D ++++++ +Y V YHN HA
Sbjct: 349 FHVAELSNNRPLSCIMFAIFQERDLLKTFRIPVDTFVTYVMTLEDHYHANVAYHNSLHAA 408
Query: 478 NVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-T 536
+V Q+ +L T ++ +DLEIL L A HD+DH G +N F T S LA++Y+
Sbjct: 409 DVTQSTHVLLSTPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 468
Query: 537 STMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVV 574
S +E+HH +L+ ++ +IFQ LS R + + +V
Sbjct: 469 SVLENHHLAVGFKLLHEDNCDIFQNLSKRQRQSLRKLV 506
>UniRef50_UPI0000E47CF4 Cluster: PREDICTED: similar to camp/cgmp
cyclic nucleotide phosphodiesterase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
camp/cgmp cyclic nucleotide phosphodiesterase -
Strongylocentrotus purpuratus
Length = 398
Score = 94.7 bits (225), Expect = 9e-18
Identities = 41/79 (51%), Positives = 59/79 (74%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F+ D +VF +YL FCGIGI NA+L+E + LE +RNQ+LL LA+++FEEQS L +V +I
Sbjct: 297 FTDSDEKVFAQYLQFCGIGINNARLYERATLEIRRNQVLLELAKTLFEEQSTLSSIVRRI 356
Query: 210 MTEARDLLKCERCAVFILD 228
M LL+CERC++ ++D
Sbjct: 357 MELLLSLLRCERCSILMVD 375
Score = 59.3 bits (137), Expect = 4e-07
Identities = 35/105 (33%), Positives = 57/105 (54%), Gaps = 9/105 (8%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----- 345
VA + +++NI++ + R N R++L MPI +V+GVAQ+INK
Sbjct: 233 VAETGETVNIANAYEDPRFNCEIDLRTGYKTRSMLSMPIKEPGGEVLGVAQVINKIGSKD 292
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALE 386
FT+ D +F + FCG+GI+N ++YE A + + +V LE
Sbjct: 293 QHEAFTDSDEKVFAQYLQFCGIGINNARLYERATLEIRRNQVLLE 337
Score = 53.6 bits (123), Expect = 2e-05
Identities = 26/50 (52%), Positives = 33/50 (66%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLD 104
+FN EID RTGYKT +L MPI G+V+GVAQ+INK + E+ D
Sbjct: 250 RFNCEIDLRTGYKTRSMLSMPIKEPGGEVLGVAQVINKIGSKDQHEAFTD 299
>UniRef50_Q4N806 Cluster: 3',5' cyclic nucleotide phosphodiesterase,
putative; n=2; Theileria|Rep: 3',5' cyclic nucleotide
phosphodiesterase, putative - Theileria parva
Length = 450
Score = 94.7 bits (225), Expect = 9e-18
Identities = 58/225 (25%), Positives = 112/225 (49%), Gaps = 5/225 (2%)
Query: 460 SVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTN 519
+++++Y YHN HA V + +R ++ E +++ L HD+ H G
Sbjct: 159 NLQQHYLANPYHNALHAATVGHMSKLLSNIVTTKRRLNPYEEFAFIISSLAHDVGHPGKT 218
Query: 520 NAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRD-YKDVMHVVETA 577
N + + T + L+++Y+ ST+E++H I+ + +N F ++ P+D + + +
Sbjct: 219 NNYLSNTSNVLSLIYNDNSTLENYHCSLLFYIIKNNTN--FYSIIPKDIWPSLRKRIIQL 276
Query: 578 ILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIA 637
ILSTD+ +F E G+FD + + LL + + A D+ PW
Sbjct: 277 ILSTDMINHFLHIDNVKEKRLQGKFDIKNDDDFWLLLVLCIKAADIGHNFLPWADHLPWT 336
Query: 638 KLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTI 682
+++ +EF+ QGD EK+Q + P+ DR + +P +Q+ F +T+
Sbjct: 337 QVLFEEFYKQGDEEKMQ-SISPLMFFDRNESRNIPILQLQFFNTM 380
>UniRef50_A7RXZ4 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 367
Score = 93.9 bits (223), Expect = 2e-17
Identities = 60/191 (31%), Positives = 94/191 (49%), Gaps = 4/191 (2%)
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESN- 556
LE+L L A HD DH G NAF T S A+LY+ S +E+HH +L S+
Sbjct: 157 LELLSLYTAAAMHDYDHPGRTNAFLVATLSHQALLYNDRSVLENHHAAAAFTLLMSDPKY 216
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGM 616
N LSP ++K + AIL+TDL +F S F G +W ++ + L
Sbjct: 217 NFLCELSPAEFKRFRFLAIEAILATDLKRHFDILSDFNAKTAEGGVNWDSEADRLLTLQF 276
Query: 617 MMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQV 676
+ D+S +K ++ + + +EF++QGD E+ + MDR+ + + Q+Q
Sbjct: 277 CIKMSDISGPSKRRDIHTLWTERIVEEFYEQGDDERAR-GMAVSPYMDRQ-QPHVAQLQD 334
Query: 677 GFIDTICLPLY 687
FI+ + PLY
Sbjct: 335 SFINHLVAPLY 345
>UniRef50_Q0V6F8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 953
Score = 93.9 bits (223), Expect = 2e-17
Identities = 74/280 (26%), Positives = 133/280 (47%), Gaps = 44/280 (15%)
Query: 468 VKYHNWRHALNVAQTMF------------------AMLKTGKMERFMSDLEILGLLVACL 509
VKYHN+RH ++V Q +F +L + + + L LL++ +
Sbjct: 346 VKYHNFRHVVDVLQALFHFLVRIGTLLPYPPNDSSGLLPKSPIAELLKPFDALTLLISAI 405
Query: 510 CHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNIFQALSPRDYK 568
HD+ H G NNAF +PLA LY+ S +E H C + I + P+ +
Sbjct: 406 GHDVGHPGVNNAFLVALNAPLAQLYNDRSVLESFH---CAAY-----SQILRRYWPQAFS 457
Query: 569 D--VMHVVETAILSTDLAMYFKKKSKFLELV-----DNGEFD-WQA---QEKKELLCGMM 617
D + ++ IL+TD+ ++FK + L D G+ D W + +E+K+L CG++
Sbjct: 458 DSAMRKLMINNILATDMGLHFKYMTDLGNLQQKIAHDQGDTDGWNSKMKEEQKDLACGVL 517
Query: 618 MTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMD----REKKDELPQ 673
+ D+ +A+ ++ + A ++ DEF +QG +E Q Q P + R+ +L +
Sbjct: 518 IKCADICNVARKFDTAAKWANILTDEFSNQGIME--QELQMPSCLFGGPPVRDDLIKLGE 575
Query: 674 MQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQD 713
Q+GF++ PL++ ++D P M N+ W++
Sbjct: 576 SQIGFMNIFACPLFEAVTDILPAMRFAVDEILANKTVWEN 615
>UniRef50_Q14432 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A; n=27; Euteleostomi|Rep:
cGMP-inhibited 3',5'-cyclic phosphodiesterase A - Homo
sapiens (Human)
Length = 1141
Score = 93.1 bits (221), Expect = 3e-17
Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 5/202 (2%)
Query: 488 KTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQ 546
K G + + LE++ L VA HD DH G NAF T +P A+LY+ S +E+HH
Sbjct: 813 KYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAA 872
Query: 547 C-VMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELV-DNGEFDW 604
+ ++ N L ++K +V AIL+TDL +F +KF V D+ DW
Sbjct: 873 AWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDDVGIDW 932
Query: 605 QAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMD 664
+ + L+C M + D++ AK E+ + + +EF++QGD E+ L MD
Sbjct: 933 TNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGD-EEASLGLPISPFMD 991
Query: 665 REKKDELPQMQVGFIDTICLPL 686
R +L +Q FI I PL
Sbjct: 992 R-SAPQLANLQESFISHIVGPL 1012
>UniRef50_A2E4B2 Cluster: Response regulator receiver domain
containing protein; n=1; Trichomonas vaginalis G3|Rep:
Response regulator receiver domain containing protein -
Trichomonas vaginalis G3
Length = 637
Score = 92.7 bits (220), Expect = 4e-17
Identities = 68/284 (23%), Positives = 128/284 (45%), Gaps = 15/284 (5%)
Query: 415 LYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWR 474
L QF+ +D+ + +F L E + ++ ++++ +HN+R
Sbjct: 270 LLDLQFNIWDIAEIKLMNLANDLFTHYGLKEIIKAKDGEIEHFLQKTQQSFNLNPFHNFR 329
Query: 475 HALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY 534
+ +A FA + K + + E L A L HD+ H GTNN FQ +T S LA++Y
Sbjct: 330 RS--IAGLQFATMILSKYKERVPPFEAAAGLFAALLHDIGHPGTNNMFQIRTSSQLALIY 387
Query: 535 STSTMEHHHFDQCVMILNSES--NNIFQALSPRDYKDV-MHVVETAILSTDLAMYFKKKS 591
+ D+ V+ +NS S + Q + D + LS LA + K
Sbjct: 388 N---------DKSVLEMNSASVGARLVQEVFSFSIDDQDFSTLRATFLSNVLATDYSKLQ 438
Query: 592 KFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE 651
KFL N + DW+ +E +++ ++ D+S + W+ ++ DE + QGD+E
Sbjct: 439 KFLAKAANIKMDWENKEHRQIALQLLTLMSDLSFAIRNWKTTSYWYGMMRDEHYIQGDME 498
Query: 652 KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
+ + N + I +MDR ++ + + +P++++ + FP
Sbjct: 499 R-KRNMKSIPLMDRRANRPNTELIKTHFEIMVMPVFQLGAKIFP 541
>UniRef50_Q1DXU2 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 900
Score = 92.7 bits (220), Expect = 4e-17
Identities = 87/333 (26%), Positives = 155/333 (46%), Gaps = 44/333 (13%)
Query: 413 YNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRP-VKYH 471
+N S +F D +L C + LQ +E++ + + + ++LSV+ +Y V YH
Sbjct: 308 WNFLSHEFSDDELVHA-AC-VMVEHALQLPELEQWRLSPEEIRSFLLSVRASYNSFVLYH 365
Query: 472 NWRHALNVAQTMFAML-KTGKMERF----------------MSDLEILGLLVACLCHDLD 514
N+RHA++V Q++F L K G + F ++ + L LL+ + HD+
Sbjct: 366 NFRHAIDVLQSVFHFLVKIGILPPFPLGSEEVSTRSGMSSILTPFDALTLLITAIGHDVG 425
Query: 515 HRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHV 573
H G NN F K +PLA LY+ S +E H IL ++F +D + + +
Sbjct: 426 HPGVNNVFLVKLNAPLAQLYNDKSVLEAFHCAAYSQILRRHWPSVF-----KDNR-LRKL 479
Query: 574 VETAILSTDLA---MYFKKKSKFLELV-DNGEFDWQAQEK-----KELLCGMMMTACDVS 624
+ +IL+TD+ ++ + K + N W + K + LLC +++ D+S
Sbjct: 480 MIDSILATDMGIHNVFMESLGKLQQSYRSNNRTTWGWEPKDIDTYRTLLCALLIKCADIS 539
Query: 625 AIAKPWEVQHRIAKLVADEFFDQGDLE-----KLQLNQQPIAMMDREKKDELPQMQVGFI 679
+A+P+ + + ++ EF +QG +E + L P + + KK Q+GF+
Sbjct: 540 NVARPFHIAEKWTDILQLEFANQGMMEAEIGMETALFGGPPELGNFVKK---ANGQIGFM 596
Query: 680 DTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
+ LPL+ ++D P M N+ RWQ
Sbjct: 597 NVFALPLFDGVADVLPDMAFAANEIRRNKCRWQ 629
>UniRef50_Q4SP32 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 763
Score = 91.9 bits (218), Expect = 7e-17
Identities = 52/179 (29%), Positives = 91/179 (50%), Gaps = 3/179 (1%)
Query: 398 DTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRW 457
D +L ++ + + F+ + TC +F + +L+ F IP D +
Sbjct: 370 DQEELLSKDLEDINKWGINIFRVAEHSHNRPLTC-IMYTIFQERDLMRTFKIPADTFVTF 428
Query: 458 ILSVKKNYRP-VKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
+L+++ +Y V YHN HA +VAQ+ +L T + +DLEIL + A HD+DH
Sbjct: 429 MLTLESHYHSNVAYHNSLHAADVAQSTHILLSTPALNAVFTDLEILAAIFAAAIHDVDHP 488
Query: 517 GTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVV 574
G +N F T S LA++Y+ S +E+HH +L ++ +IFQ L+ + + + +V
Sbjct: 489 GVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLTKKQRQTLRRMV 547
Score = 44.8 bits (101), Expect = 0.010
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 617 MMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQV 676
M+ D+S KP ++ + + DEFF QGD E+ + + M D+ + + QV
Sbjct: 622 MVHCADLSNPTKPLDLYRQWTDRIMDEFFHQGDRER-ERGMEISPMCDKHTA-SVERTQV 679
Query: 677 GFIDTICLPLYKVLSD-TFPWMTPLRTGTADNRRRWQDL 714
GFID I PL++ +D P + DNR +Q +
Sbjct: 680 GFIDYIVHPLWETWADLVHPDAQDILDTLEDNRNWYQSM 718
>UniRef50_O43851 Cluster: PDE4C-delta109; n=18; Bilateria|Rep:
PDE4C-delta109 - Homo sapiens (Human)
Length = 427
Score = 91.5 bits (217), Expect = 9e-17
Identities = 73/251 (29%), Positives = 116/251 (46%), Gaps = 12/251 (4%)
Query: 497 SDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSES 555
+DLEIL L A HD+DH G +N F T S LA++Y+ S +E+HH +L +E+
Sbjct: 129 TDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAEN 188
Query: 556 NNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDN------GEFDWQAQEK 609
+IFQ LS + + +V +L+TD++ + + +V+ G
Sbjct: 189 CDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSD 248
Query: 610 KELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQ-LNQQPIAMMDREKK 668
+ + ++ D+S KP + + + EFF QGD E+ L+ P M D+
Sbjct: 249 RIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISP--MCDKHTA 306
Query: 669 DELPQMQVGFIDTICLPLYKVLSD-TFPWMTPLRTGTADNRRRWQDLAEKVDMGLTWIDH 727
+ + QVGFID I PL++ +D P L DNR +Q + LT +
Sbjct: 307 -SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPER 365
Query: 728 DTIDKPVEEFT 738
D D+ E T
Sbjct: 366 DGPDRFQFELT 376
>UniRef50_Q4SI77 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 750
Score = 89.4 bits (212), Expect = 4e-16
Identities = 63/194 (32%), Positives = 100/194 (51%), Gaps = 9/194 (4%)
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQC-VMILNSESN 556
LE++ L VA HD DH G NAF T +P A+LY+ S +E+HH + L+
Sbjct: 442 LELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAAAAWSLYLSRPEF 501
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF---LELVDNGEFDWQAQEKKELL 613
N L ++K +V AIL+TDL +F ++F + V++ DW + + L+
Sbjct: 502 NFLVNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNSKVNDVNSPGIDWTNENDRLLV 561
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELP 672
C + + D++ AK ++ + + + +EF++QGD E KL L P MDR +L
Sbjct: 562 CQVCIKLADINGPAKIRDLHLQWTEGIVNEFYEQGDEEAKLGLPVSP--FMDR-SSPQLA 618
Query: 673 QMQVGFIDTICLPL 686
++Q FI I PL
Sbjct: 619 KLQESFITHIVGPL 632
Score = 35.5 bits (78), Expect = 6.1
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 5/79 (6%)
Query: 411 ETYNLYSFQFHDF-DLTDEDTCR----ATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY 465
E N ++FQ D D T T R T +F L E F IP + +++ Y
Sbjct: 305 ERLNTWNFQIFDLVDKTGGKTGRILSYVTYTLFQDACLFEIFKIPVREFMTYFSALESGY 364
Query: 466 RPVKYHNWRHALNVAQTMF 484
R + YHN HA +V ++
Sbjct: 365 RDIPYHNRVHAADVLHAVW 383
>UniRef50_Q54HY3 Cluster: Putative uncharacterized protein Pde4;
n=2; Dictyostelium discoideum|Rep: Putative
uncharacterized protein Pde4 - Dictyostelium discoideum
AX4
Length = 771
Score = 89.4 bits (212), Expect = 4e-16
Identities = 46/165 (27%), Positives = 86/165 (52%), Gaps = 3/165 (1%)
Query: 437 MFLQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKMERF 495
+F + + EKF I D ++ ++ Y YHN HA +V + ++ +F
Sbjct: 306 LFSRHKFFEKFKIGIDCFKNFMRKIESGYDSTNPYHNSIHATDVLHNLNYFIEKS-FGKF 364
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSE 554
++D+E+ +++A + HD H G NN FQ ++S LA+ Y+ S +E++H Q +I+N
Sbjct: 365 LTDIELFSMILAAIIHDFKHPGVNNHFQINSKSRLALKYNDKSILENYHLHQAFIIMNEP 424
Query: 555 SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDN 599
+ I LS K++ + +LSTD+A +F +F + ++
Sbjct: 425 ESGILLKLSDSVRKEIRETIIALVLSTDMAKHFNLVGRFKSMANS 469
Score = 53.2 bits (122), Expect = 3e-05
Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 612 LLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDEL 671
LL + + D+S +KPW + + V EF+ QGD EK + N A MDR K
Sbjct: 583 LLMKISIKCADISNPSKPWNLYTNWSNRVTSEFYKQGDKEK-ESNMDVSAFMDR-NKPAT 640
Query: 672 PQMQVGFIDTICLPLYKVLSDTFP 695
+ Q+ FI+ P+Y++ S FP
Sbjct: 641 TKCQINFINIFVAPIYEIWSHHFP 664
>UniRef50_A0BZK9 Cluster: Chromosome undetermined scaffold_139,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_139,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 987
Score = 89.4 bits (212), Expect = 4e-16
Identities = 78/311 (25%), Positives = 138/311 (44%), Gaps = 19/311 (6%)
Query: 417 SFQFHDFDLTDEDTCRATLRMFLQCE-LVEKFHIPYDVLCRWILSVKKNYRPVK--YHNW 473
SF F+ DLT + + + L+ ++ F IP + L +I ++ NY YHN+
Sbjct: 680 SFDFNIMDLTSQIQKHRVVWVILKKNGHLDDFQIPSENLQSFIKEMEYNYNVNNNPYHNY 739
Query: 474 RHALNVAQTMF----AMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESP 529
H + V QT + +T K + + + L+++ HD+ H G N F+ + S
Sbjct: 740 DHGITVMQTAHYFCSELAQTSK-SKIIDNFNRFILMISSFGHDVGHTGKTNVFEINSLSD 798
Query: 530 LAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFK 588
LAI Y S +E HH + +L + +NI L+ +++++ + ILSTD++ +F
Sbjct: 799 LAIRYHDKSVLEQHHAALTIQVLKNPQSNILVNLNQQEFRNFRKGLIANILSTDMSEHFT 858
Query: 589 KKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQG 648
F +N D+ ++L G +M D K + + + V EF Q
Sbjct: 859 LLKDF----ENRPTDF---NDCKILSGYIMHTSDFGGAGKKTNLSIKWSSRVNQEFSIQY 911
Query: 649 DLE-KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTF-PWMTPLRTGTAD 706
LE +L QQP M D + + ++GF+ I P Y + S+ + D
Sbjct: 912 KLEGELGYPQQPY-MKDLHIPHVMAKSEIGFLKVIVRPCYALFSEFLEDRLKHCMANIDD 970
Query: 707 NRRRWQDLAEK 717
+ W+ + +K
Sbjct: 971 TIQHWEKIVKK 981
>UniRef50_Q13370 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase B; n=26; Euteleostomi|Rep:
cGMP-inhibited 3',5'-cyclic phosphodiesterase B - Homo
sapiens (Human)
Length = 1112
Score = 88.2 bits (209), Expect = 8e-16
Identities = 59/193 (30%), Positives = 97/193 (50%), Gaps = 7/193 (3%)
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQC-VMILNSESN 556
LE++ L VA HD DH G NAF T +P A+LY+ S +E+HH + L+
Sbjct: 809 LELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEY 868
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF---LELVDNGEFDWQAQEKKELL 613
N L ++K +V AIL+TDL +F ++F V++ +W + + L+
Sbjct: 869 NFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSNENDRLLV 928
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQ 673
C + + D++ AK ++ + + + +EF++QGD E+ L MDR +L +
Sbjct: 929 CQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGD-EEANLGLPISPFMDR-SSPQLAK 986
Query: 674 MQVGFIDTICLPL 686
+Q FI I PL
Sbjct: 987 LQESFITHIVGPL 999
>UniRef50_Q53I59 Cluster: Cyclic nucleotide specific
phosphodiesterase; n=3; Trypanosoma cruzi|Rep: Cyclic
nucleotide specific phosphodiesterase - Trypanosoma
cruzi
Length = 924
Score = 87.4 bits (207), Expect = 1e-15
Identities = 57/240 (23%), Positives = 112/240 (46%), Gaps = 6/240 (2%)
Query: 458 ILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGK-MERFMSDLEILGLLVACLCHDLDHR 516
+ +V+ NYRP YHN HA +V Q F+++ K + ++ LE A L HD+ H
Sbjct: 355 VAAVENNYRPNPYHNAIHAADVLQGTFSLVSAAKPLMEHLTPLECKAAAFAALTHDVCHP 414
Query: 517 GTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVE 575
G NAF + P++ +S T+E H +LN + ++ + + ++V
Sbjct: 415 GRTNAFLAAVQDPVSFKFSGKGTLEQLHTVTAFELLNVTEFDFTSSMDNASFLEFKNIVS 474
Query: 576 TAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHR 635
I TD++++ + +K + G FD +E + +++ A D+ A ++ + +
Sbjct: 475 HLIGHTDMSLHSETIAKHGAKLSAGGFDCTCKEDRLEALSLLLHAADIGASSRGVAIARK 534
Query: 636 IAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFP 695
++ EF DQ + E+ + P+ + + + Q+ F+D +P + +L FP
Sbjct: 535 WL-VILQEFADQAEDERRR--GLPVT-PGFDTPSSVEKSQIPFLDFFVIPTFDLLHQLFP 590
>UniRef50_A0BZW8 Cluster: Chromosome undetermined scaffold_14, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_14,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 454
Score = 87.0 bits (206), Expect = 2e-15
Identities = 58/222 (26%), Positives = 110/222 (49%), Gaps = 18/222 (8%)
Query: 444 VEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILG 503
++ +P +VL I + NY V YHN+ HA ++Q +F+ +++F + LEI
Sbjct: 154 LDTIKVPKNVLNDLITEIIMNYNVVPYHNFTHAFQLSQLLFSCYMKSDLKKFCNQLEIFS 213
Query: 504 LLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILN-SESNNIFQA 561
++A L HDL+H+G NN ++ K +L S + +E+ H I+ + ++ FQ
Sbjct: 214 AILAGLGHDLNHKGVNNMYKIKKSKKFNVLTSEIAVLENMHCATFFNIIQLNRQHDFFQY 273
Query: 562 LSPRDYKDV-MHVVETAILSTDLAMYFKKKSKFL---------------ELVDNGEFDWQ 605
++ + +++ ++ T+IL+TD++ + K +KF EL+D F +
Sbjct: 274 MTNDEERNLAKRLIITSILATDMSKHNKLLAKFQKRVESTKQFEQGEKNELIDMQRFSNE 333
Query: 606 AQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQ 647
E + + +M+ ACD+S + + L+ EF DQ
Sbjct: 334 RLEDRIFILNIMVHACDISNPTMKFNNYMNWSYLLTQEFNDQ 375
>UniRef50_Q01CI7 Cluster: Cyclic GMP phosphodiesterase; n=1;
Ostreococcus tauri|Rep: Cyclic GMP phosphodiesterase -
Ostreococcus tauri
Length = 526
Score = 86.6 bits (205), Expect = 2e-15
Identities = 79/341 (23%), Positives = 154/341 (45%), Gaps = 18/341 (5%)
Query: 393 TASAEDTSKLCQDEIPSAETYNLYSF-QFHDFDLTDEDTCRATLRMFLQCELVEKFHIPY 451
T + S C+ I S +++ +F + + + T + ++ +F +L + +
Sbjct: 185 TTDSSYVSLQCEGSITSWRNFDVLAFAKCCNNEATIGPLEKLSMELFEYFDLFKTLPLKR 244
Query: 452 DVLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCH 511
+ R++ ++ +YR YHN HA +V Q ++T ++ + + I LL++ + H
Sbjct: 245 SSVKRFLADIEVSYRDNDYHNGVHAADVTQAAAYFIETSLRDQ-IEPIHIFALLLSAVVH 303
Query: 512 DLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMILNSESNNIFQALSPRDYKDV 570
D+ H G NNA+ ++ +A ++ S E+ H +L + ++ + + D V
Sbjct: 304 DVGHPGLNNAYLVARQTDVAERWNNVSVNENGHLYTANTLL--KQYDVLKDFADDDRVLV 361
Query: 571 MHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQA---QEKKE-----LLCGMMMTACD 622
+ +++ +L TD+ ++ K +E V+ EFD +A + KE + + D
Sbjct: 362 LKLLQKMVLCTDMEVHADLVKKVIEAVER-EFDKEAGLLKPVKEWGEVWIPLAFALHCAD 420
Query: 623 VSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDE--LPQMQVGFID 680
+S A+P+++ A + +EFF QGDL++ P MDR Q+GFI
Sbjct: 421 ISNPARPYDLALYWANAIVEEFFKQGDLQRGFQMSVP-GFMDRRLASPAGTQSSQLGFIK 479
Query: 681 TICLPLYKVLSDTFPW-MTPLRTGTADNRRRWQDLAEKVDM 720
I P ++L P L + N R++D K M
Sbjct: 480 VIVKPSLELLDSYMPQAAAELLSHIETNIERYEDDVNKALM 520
>UniRef50_Q4RSB8 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF15000, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 737
Score = 85.0 bits (201), Expect = 8e-15
Identities = 61/202 (30%), Positives = 97/202 (48%), Gaps = 7/202 (3%)
Query: 490 GKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQC- 547
G + + LE++ L VA HD DH G NAF T +P A+LY+ S +E+HH
Sbjct: 413 GCLSGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAW 472
Query: 548 VMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGE---FDW 604
+ ++ N L ++K +V AIL+TDL +F ++F V + DW
Sbjct: 473 NLFMSHPEYNFLVNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKVGDDPSTGIDW 532
Query: 605 QAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMD 664
+ + L+C M + DV+ K ++ + + + +EF+ QGD E+ L MD
Sbjct: 533 SNENDRLLVCQMCIKLADVNGPLKCKDLHLQWTEGIVNEFYQQGD-EESTLGLPISPFMD 591
Query: 665 REKKDELPQMQVGFIDTICLPL 686
R +L ++Q FI I PL
Sbjct: 592 R-AAPQLAKLQESFITHIVGPL 612
>UniRef50_A2FCG2 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 439
Score = 83.4 bits (197), Expect = 2e-14
Identities = 83/379 (21%), Positives = 170/379 (44%), Gaps = 24/379 (6%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----- 345
V ++ LNISDV + R + S ++ L PI++ K+++GV Q++NK
Sbjct: 71 VCKNKSLLNISDVTKDSRYDPTEDQRTSFVSKSFLVAPIMDEEKNILGVIQIVNKIPGYD 130
Query: 346 ---FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKL 402
FT+ D + A F G I + + + + + + ++SAE +
Sbjct: 131 GLVFTKDDERLVGAMTSFAGYSISKVKNKD--------KNITTDAVFDLFSSSAEQIGVV 182
Query: 403 CQD-EIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSV 461
Q + E L + Q + L R + F L+++ +I + ++++
Sbjct: 183 LQQMRLSQEEETTLTNPQAYMRGLQMNLKLRFMIFCFTSFNLLDQLNIQFITFFQFLMLF 242
Query: 462 KKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNA 521
+ + + YHN +L+ Q ++ +LK ++ + + +E+ LL+A L H+ +H+G +
Sbjct: 243 QTMGKDLPYHNSDQSLDTLQYVYVILKQTEVSKQLDTIELFALLMASLLHNTNHKGEHGG 302
Query: 522 FQTKTESPLAILYSTS-TMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILS 580
+T+ PL IL+ E D + +L ++S I A+ P D + + T ++
Sbjct: 303 LLIRTKLPLEILFKNQPPAETAQADAAIQLLTNKSVAILDAI-PDDVRAKFWNIFTQLI- 360
Query: 581 TDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIA-KPWEV-QHRIAK 638
L+ K+S F++L +G+ Q + L C IA K E+ + + +
Sbjct: 361 --LSSGIYKESDFIQLWKSGDHSKLNQMRLILKIANSGNVCRPYDIAMKHGELKKQELQQ 418
Query: 639 LVADEFFDQGDLEKLQLNQ 657
++ +E G+L ++L++
Sbjct: 419 ILQEEKVVYGELLLIRLSR 437
>UniRef50_A0EF18 Cluster: Chromosome undetermined scaffold_92, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_92,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 929
Score = 83.0 bits (196), Expect = 3e-14
Identities = 80/312 (25%), Positives = 136/312 (43%), Gaps = 24/312 (7%)
Query: 417 SFQFHDFDLTDE--DTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNY--RPVKYHN 472
SF F+ F + + + R ++ + +E F I + LC ++ ++ Y R +HN
Sbjct: 626 SFDFNIFKIENNSIEKQRIVYQILNRNNFIEIFEIDKNRLCEFLGELEYRYDKRRNPFHN 685
Query: 473 WRHALNVAQT----MFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTES 528
+ H +NV + M M+ + + L L L+++ LCHD+ H G N F+ S
Sbjct: 686 YNHGVNVMHSCHVIMNKMINQPQYKVLFDQLTKLSLILSGLCHDVGHTGRTNIFEINNFS 745
Query: 529 PLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYF 587
AI Y + +E +H + +L E N + + R +++ ++ I+ TD +F
Sbjct: 746 EKAIRYHDKNVLEQYHAATALKLLLKERMNFLKNVDFRQFRE--KFIQN-IIFTDKQEHF 802
Query: 588 KKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQ 647
KF E N E D +++ GM++ D + + W + + + V EF Q
Sbjct: 803 -NLLKFFEA--NNEKD------IKIITGMIIHTSDFAGASAKWPISKQWSLRVNQEFQAQ 853
Query: 648 GDLE-KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTAD 706
+ E +L L QQP M D +K L + ++GF PLY LS R D
Sbjct: 854 FEEEGRLGLPQQPF-MKDLQKISVLSKSEIGFYKFFVRPLYVSLSKFMDHQLQDRIDNID 912
Query: 707 NR-RRWQDLAEK 717
W LA +
Sbjct: 913 ETIIEWDSLASQ 924
>UniRef50_A6R1R4 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 839
Score = 82.6 bits (195), Expect = 4e-14
Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 19/219 (8%)
Query: 511 HDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKD 569
HD+ H G NN F + +PLA LY+ TS +E H +L S + + R
Sbjct: 299 HDVGHPGVNNVFLVRLNAPLAQLYNDTSVLESFHCAAYSQLLRSYWPSFVMDMKLRK--- 355
Query: 570 VMHVVETAILSTDLAMYFK-------KKSKFLELVDNGEF-DWQAQEKKELLCGMMMTAC 621
++ ++IL+TD+ ++FK + K+ E + D + + + LLCG++M
Sbjct: 356 ---LMISSILATDMGVHFKFMESLGKLREKYHETHSTDRWTDNEIETNRALLCGLLMKCA 412
Query: 622 DVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQM---QVGF 678
D+S +A+ W++ R ++ +EF QG++EK + + + +P++ Q+ F
Sbjct: 413 DISNVARTWDIAKRWTNVLQEEFAQQGNMEK-TIGMETALFGGPPELGNVPKLAKSQINF 471
Query: 679 IDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
I LPL++ L+ P M N+ W+++ +
Sbjct: 472 IKLFALPLFENLAYLLPDMAFTTVEIRRNKSIWREIINR 510
>UniRef50_UPI000023CCA1 Cluster: hypothetical protein FG06914.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG06914.1 - Gibberella zeae PH-1
Length = 886
Score = 81.0 bits (191), Expect = 1e-13
Identities = 55/215 (25%), Positives = 102/215 (47%), Gaps = 15/215 (6%)
Query: 492 MERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYST-STMEHHHFDQCVMI 550
M ++ E L LL+ + HD+ H G NN F +PLA LY+ S +E H I
Sbjct: 353 MASLITPFEALTLLITAIGHDVGHPGVNNGFLVTLNAPLAQLYNDRSVLESFHCAAYSQI 412
Query: 551 LNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVD-----NGEFDW- 604
L + F+ R+ ++ ++IL+TD+ ++F K ++ + N W
Sbjct: 413 LRRYWPSAFEDTKMRN------LMISSILATDMGLHFDYMKKLGDVQERLQASNTTDGWN 466
Query: 605 --QAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAM 662
Q +E K L C +++ D+S +A+ E+ + ++++EF Q +E Q +
Sbjct: 467 GRQIEENKSLACSLLIKCADISNVARSHEIALQWTYILSEEFSRQASMESELSIQSSLMT 526
Query: 663 MDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWM 697
++ L + Q+GF++ PL++ ++D P M
Sbjct: 527 PPKQDMASLAKGQLGFMNLFATPLFQGVADIMPTM 561
>UniRef50_Q7YYN8 Cluster: Phosphdiesterase, possible; n=2;
Cryptosporidium|Rep: Phosphdiesterase, possible -
Cryptosporidium parvum
Length = 1001
Score = 77.4 bits (182), Expect = 2e-12
Identities = 64/259 (24%), Positives = 120/259 (46%), Gaps = 33/259 (12%)
Query: 461 VKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNN 520
+K + +HN+ HA++++ T+ L + +++ LE L+++ L HDLDH G N
Sbjct: 714 IKYYHEENPFHNFHHAVSISITLNNWLDKPSVRHYVNSLEAYCLIISSLSHDLDHPGLTN 773
Query: 521 -------------------------AFQTKTESPLAILYSTSTMEHHHFDQCVMILNSES 555
Q T S L I + S +E+HH +ILN E+
Sbjct: 774 DMIKELNILSRKVLQEFTTDEQFFEILQNNTLSTLKIYNNFSVLENHHSSLLFVILNDEA 833
Query: 556 NNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQE----KKE 611
+NI + + Y ++ ++ +IL TD+ + + L N + ++ E KK+
Sbjct: 834 SNIMPPTTSKYYSELHKMMINSILFTDMFQHKYLRDLVLNFNKNYSSNSRSIEVEAQKKK 893
Query: 612 LLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDEL 671
L +++ + D+S + + ++LV +E +Q L KL LN I++ D +
Sbjct: 894 LYLLILLHSVDISNPLMNTNIYLKWSRLVYEELENQKKL-KLMLN---ISLNDTTDTYDY 949
Query: 672 PQMQVGFIDTICLPLYKVL 690
++Q FI +IC+P ++ L
Sbjct: 950 TKLQTSFISSICIPYFQAL 968
>UniRef50_A3FPW6 Cluster: Phosphdiesterase, putative; n=1;
Cryptosporidium parvum Iowa II|Rep: Phosphdiesterase,
putative - Cryptosporidium parvum Iowa II
Length = 1206
Score = 77.4 bits (182), Expect = 2e-12
Identities = 64/259 (24%), Positives = 120/259 (46%), Gaps = 33/259 (12%)
Query: 461 VKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNN 520
+K + +HN+ HA++++ T+ L + +++ LE L+++ L HDLDH G N
Sbjct: 919 IKYYHEENPFHNFHHAVSISITLNNWLDKPSVRHYVNSLEAYCLIISSLSHDLDHPGLTN 978
Query: 521 -------------------------AFQTKTESPLAILYSTSTMEHHHFDQCVMILNSES 555
Q T S L I + S +E+HH +ILN E+
Sbjct: 979 DMIKELNILSRKVLQEFTTDEQFFEILQNNTLSTLKIYNNFSVLENHHSSLLFVILNDEA 1038
Query: 556 NNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQE----KKE 611
+NI + + Y ++ ++ +IL TD+ + + L N + ++ E KK+
Sbjct: 1039 SNIMPPTTSKYYSELHKMMINSILFTDMFQHKYLRDLVLNFNKNYSSNSRSIEVEAQKKK 1098
Query: 612 LLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDEL 671
L +++ + D+S + + ++LV +E +Q L KL LN I++ D +
Sbjct: 1099 LYLLILLHSVDISNPLMNTNIYLKWSRLVYEELENQKKL-KLMLN---ISLNDTTDTYDY 1154
Query: 672 PQMQVGFIDTICLPLYKVL 690
++Q FI +IC+P ++ L
Sbjct: 1155 TKLQTSFISSICIPYFQAL 1173
>UniRef50_A7TPP3 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 518
Score = 77.4 bits (182), Expect = 2e-12
Identities = 78/333 (23%), Positives = 151/333 (45%), Gaps = 32/333 (9%)
Query: 406 EIPSAETYNLYSF---QFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVK 462
++P + Y L F +F L +++ + + + I + L + S++
Sbjct: 197 KVPKDDDYYLDLFATWKFSANSLNNQELIYCSFLLIKKLSTESNIPISDNKLLLLLFSLE 256
Query: 463 KNYRPV-KYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNA 521
+Y V K+HN+RHA++V Q + + K+ + L L +A + HD+ H GTNN
Sbjct: 257 ASYHQVNKFHNFRHAVDVMQATYQLCD--KLLTKDDHIYKLLLCMAAIGHDIAHPGTNNN 314
Query: 522 FQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILS 580
+S +A+ + + S +E+ H +L + ++ ++ + +D ++++ +IL+
Sbjct: 315 LLVNYKSSVALHFDNESVLENFHQVLFQQLLFDQWPSLIDIVTQCEKRDKFNIIKDSILA 374
Query: 581 TDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLV 640
TD+A++ S++++ + N E D++ L ++ A D+S + +P V + A L+
Sbjct: 375 TDMAIH----SRYVKQL-NPEEDFRINN----LISFIIKAADISNVTRPLHVSAQWALLI 425
Query: 641 ADEFFDQGDLEKLQ-LNQQPIAMMDREKKDE---------------LPQMQVGFIDTICL 684
+ EF D LE + N D KD+ LP Q+ FI+T
Sbjct: 426 SLEFEDCALLETYEKTNTTSCIDGDENIKDDDLLLSPDDLVKKYPSLPNGQLFFINTFAE 485
Query: 685 PLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
+ LS +FP + L N+ W D K
Sbjct: 486 EFFNKLSLSFPSLQYLSDNIQTNKAYWLDKKSK 518
>UniRef50_Q6CHK1 Cluster: Similar to tr|Q8NJP9 Candida albicans High
affinity cAMP phosphodiesterase; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q8NJP9 Candida albicans
High affinity cAMP phosphodiesterase - Yarrowia
lipolytica (Candida lipolytica)
Length = 626
Score = 76.6 bits (180), Expect = 3e-12
Identities = 81/329 (24%), Positives = 147/329 (44%), Gaps = 43/329 (13%)
Query: 418 FQFHDFDLTDEDTCRATLRMF---LQCELVEKFHIPYDVLCRWILSVKKNYRPVK-YHNW 473
+ + F+L+ ++ L MF L +E + + L R+++ ++ Y YHN+
Sbjct: 303 WDYDPFELSYDELVIMALVMFQYILSLPGLEPYRLEEPELVRFLIMMRDAYHHENPYHNF 362
Query: 474 RHALNVAQTMFAML-KTGKME------------------RFMSDLEILGLLVACLCHDLD 514
RHA++V Q F L + G + + E L +++A + HD+
Sbjct: 363 RHAIDVMQATFQFLIRLGCLPPPPFKRAPNCSMIPPIGPAVFTPAESLVVIIAAIGHDIS 422
Query: 515 HRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHV 573
H G NAF + SP+A +++ S +E +H CV LN N + A K + +
Sbjct: 423 HPGVTNAFLVSSHSPMAQVFNDKSVLESYH--ACV--LNRVLNIFWPATQEPHLKKL--I 476
Query: 574 VETAILSTDLAMYFKKKSKFLELVD----------NGEFDWQAQEKKELLCGMMMTACDV 623
VE ++L+TD+A +F ++ EL N E + ++L+ M+M DV
Sbjct: 477 VE-SVLATDMAQHFNYVDRWNELSARCRSKGKGRCNEERGNLSPADRQLVGSMIMKCADV 535
Query: 624 SAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTIC 683
S + + ++ + +++ EF + D+E N Q + + K L Q QV F++
Sbjct: 536 SNVTRRLDLAEKWGRVLQCEFSEVKDVE-TDCNVQTLP-PNCGKNANLAQSQVSFLNIFA 593
Query: 684 LPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
PL++ SD FP +N+ W+
Sbjct: 594 YPLFQQFSDAFPEFGYAFKTLQENKAVWE 622
>UniRef50_UPI0001554EBF Cluster: PREDICTED: similar to cyclic
nucleotide phophodiesterase, partial; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
cyclic nucleotide phophodiesterase, partial -
Ornithorhynchus anatinus
Length = 340
Score = 76.2 bits (179), Expect = 4e-12
Identities = 45/154 (29%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQC-VMILNSESN 556
LE++ L VA HD DH G NAF T +P A+LY+ S +E+HH + L+
Sbjct: 187 LELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLFLSRPEY 246
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF---LELVDNGEFDWQAQEKKELL 613
N L ++K +V AIL+TDL +F ++F V++ +W + + L+
Sbjct: 247 NFLSNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSSGIEWSNENDRLLV 306
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQ 647
C + + D++ AK ++ + + + +EF++Q
Sbjct: 307 CQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQ 340
Score = 35.5 bits (78), Expect = 6.1
Identities = 15/31 (48%), Positives = 18/31 (58%)
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESP 529
LE++ L VA HD DH G NAF T +P
Sbjct: 110 LELMALYVAAAMHDYDHPGRTNAFLVATNAP 140
>UniRef50_A4RUJ3 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 614
Score = 75.4 bits (177), Expect = 6e-12
Identities = 63/262 (24%), Positives = 114/262 (43%), Gaps = 17/262 (6%)
Query: 447 FH-IPYD--VLCRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILG 503
FH +P D + +I +++ YR YHN HA +V Q +++T +E + +
Sbjct: 328 FHALPLDRNSVSNFIADIERKYRDNDYHNRVHATDVTQAAAYLIET-SLESQIEPIHTFA 386
Query: 504 LLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQAL 562
+LVA + HD+ H G NN F +S A ++ S E+ H +L + +
Sbjct: 387 MLVAAMSHDVGHPGVNNTFLVNCKSAEAERWNDVSVNENGHLFTAFSLLKKHA--VLAKF 444
Query: 563 SPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELL--------C 614
+ + D+ ++ I+ TD+ + + + L+ +++ E D + K +
Sbjct: 445 TDSEQSDLKKWLQKMIMYTDMEFHGELTQRMLKEIED-EQDEETNSIKPIKQWQNIWVPL 503
Query: 615 GMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELPQ 673
+ D+S A+P+E+ A+ V EF+ QGD + KL + +P
Sbjct: 504 AFALHCADISNPARPYELALAWAQAVTAEFYKQGDRQRKLGMRVEPFMDRSLAGPASTQS 563
Query: 674 MQVGFIDTICLPLYKVLSDTFP 695
Q+GFI + P VL P
Sbjct: 564 NQLGFIKLVVKPSLCVLEAFMP 585
>UniRef50_Q5CXM2 Cluster: Membrane associated HD superfamily cyclic
nucleotide phosphodiesterase domain containing protein;
n=2; Cryptosporidium|Rep: Membrane associated HD
superfamily cyclic nucleotide phosphodiesterase domain
containing protein - Cryptosporidium parvum Iowa II
Length = 1967
Score = 75.4 bits (177), Expect = 6e-12
Identities = 42/132 (31%), Positives = 71/132 (53%), Gaps = 2/132 (1%)
Query: 468 VKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTE 527
+ YHN HAL V Q + +L+ + ++DL LL A LCHD+DH G NN F T +
Sbjct: 1549 IPYHNIFHALQVVQVCYIILRNFGIMLVLNDLNKFILLFAALCHDIDHPGVNNCFLTISN 1608
Query: 528 SPLAILYS-TSTMEHHHFDQCVMILNS-ESNNIFQALSPRDYKDVMHVVETAILSTDLAM 585
S LA+ Y+ S +E+HH + +L+ + +I + + + K+ + ++LSTD++
Sbjct: 1609 SKLALKYNDNSILENHHCNYIFSLLDKCQDLDIRKNFNDFEKKNFRRIFIRSVLSTDMSY 1668
Query: 586 YFKKKSKFLELV 597
+ S E +
Sbjct: 1669 HNTLLSNLEEFI 1680
Score = 46.0 bits (104), Expect = 0.004
Identities = 50/208 (24%), Positives = 85/208 (40%), Gaps = 15/208 (7%)
Query: 510 CHDLDHRGTNNAFQTKTESPLAILYSTST-MEHHH-----FDQCVMILNSESNNIFQALS 563
C DLD R N F+ K + I ST M +H+ ++ + N+ +NNI
Sbjct: 1636 CQDLDIRKNFNDFEKKNFRRIFIRSVLSTDMSYHNTLLSNLEEFISTNNNNNNNINNNNY 1695
Query: 564 PRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDV 623
+ + E + + ++ + K L +D + KE L ++ A D+
Sbjct: 1696 YYCHNQNLIFDEEELNNNNINI------KMLGEIDENSL--LIKMDKEFLIETLLHAADI 1747
Query: 624 SAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTIC 683
S P+ + + + L+ +EF Q LE Q MD + + Q+GF++ I
Sbjct: 1748 SNPITPFPICAKWSSLIVEEFNYQSKLES-QFGLPITPFMDLKDDITKIEAQIGFLEFII 1806
Query: 684 LPLYKVLSDTFPWMTPLRTGTADNRRRW 711
+P +K+LS P L NR W
Sbjct: 1807 IPQWKLLSRIIPKSIILLKQAEKNRELW 1834
>UniRef50_Q57ZK5 Cluster: 3', 5'-cyclic nucleotide
phosphodiesterase, putative; n=1; Trypanosoma
brucei|Rep: 3', 5'-cyclic nucleotide phosphodiesterase,
putative - Trypanosoma brucei
Length = 909
Score = 75.4 bits (177), Expect = 6e-12
Identities = 51/243 (20%), Positives = 102/243 (41%), Gaps = 6/243 (2%)
Query: 455 CRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGK-MERFMSDLEILGLLVACLCHDL 513
C + +++ NYRP +HN A +V Q +F++ K + R ++ +E+ L+ A + D+
Sbjct: 350 CHMVAAIENNYRPNPFHNAVRAADVVQAVFSLASATKPLMRHVTLVELKALVFAAVALDV 409
Query: 514 DHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMH 572
H G N F +T PL Y T+E H ++ N ++ +
Sbjct: 410 RHPGRTNEFLVRTCDPLCYRYPGPGTLEQMHVATAFQLVEVPELNFTCRMNDESFLRFKT 469
Query: 573 VVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEV 632
+V I TD A+ + G FD+ A + + +++ A D I++ ++
Sbjct: 470 IVSKLICRTDTAVLEDHLEHWRAKAREGGFDYGAPDDRVDALSLLLLAADFGVISRGADI 529
Query: 633 QHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSD 692
+ L + + + L P + + + Q+ F+D++ +PL+ +
Sbjct: 530 AAKWLVLTEEHAAQAQEERRRGLPVTP----GFDLPTSVGRSQIAFLDSVVIPLFNQVQQ 585
Query: 693 TFP 695
FP
Sbjct: 586 LFP 588
>UniRef50_Q1JT10 Cluster: Phosphodiesterase, putative; n=2;
Eukaryota|Rep: Phosphodiesterase, putative - Toxoplasma
gondii RH
Length = 2092
Score = 73.3 bits (172), Expect = 2e-11
Identities = 33/75 (44%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
Query: 470 YHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESP 529
YHN+ HA++V Q + L +S +E LG+L+A LCHD+DH G NNAF + P
Sbjct: 1757 YHNFYHAIHVFQVCWMFLSAYGCRNILSPIEQLGILLAALCHDVDHPGVNNAFLRASLHP 1816
Query: 530 LAILYS-TSTMEHHH 543
L+I+Y+ S +E+HH
Sbjct: 1817 LSIMYNDKSVLENHH 1831
Score = 46.8 bits (106), Expect = 0.002
Identities = 35/164 (21%), Positives = 69/164 (42%), Gaps = 4/164 (2%)
Query: 552 NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF---LELVDNGEFDWQAQE 608
+ S + F+ + ++ +V AI STD+ ++ + ++ N + + ++
Sbjct: 1868 SGSSGSRFEGRIVPSFSELRKIVIQAIFSTDMELFRQHHDAMKRRAQMKTNDREELEGED 1927
Query: 609 KKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKK 668
+ LL ++ D+ + A LV EF Q DLE+ + MD +
Sbjct: 1928 DRNLLVTCLIHCADICNPVMSEGRNVQWASLVTQEFNAQVDLER-RYGLPVSVFMDARTE 1986
Query: 669 DELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQ 712
+ Q Q+GF+ + L ++ L+D P ++ L N WQ
Sbjct: 1987 LQRTQSQIGFLSFVVLDQFRALADLIPEVSELVVQGEKNLEMWQ 2030
>UniRef50_Q3KVL8 Cluster: High-affinity phosphodiesterase; n=4;
Eukaryota|Rep: High-affinity phosphodiesterase -
Cryptococcus neoformans var. neoformans
Length = 555
Score = 70.5 bits (165), Expect = 2e-10
Identities = 63/255 (24%), Positives = 121/255 (47%), Gaps = 38/255 (14%)
Query: 489 TGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQC 547
T + M +IL +L+A + HD+ H G +NAF PL+ +Y S +E+ H
Sbjct: 307 TKRAREIMRPQDILAVLIAAMGHDVGHPGLSNAFM--VSCPLSQVYEDKSVLENMHCMLV 364
Query: 548 VMIL----------NSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYF---KKKSKFL 594
V +L ++S++ QA+S D K V+ ++IL+TD++++F ++ +F
Sbjct: 365 VQLLRKYGFGFLIERTKSSSGEQAVSNLDQKSFRQVLYSSILATDMSLHFAWVQRLKEFD 424
Query: 595 ELVDNGEFDWQAQEKKELLCGMMMTACDVS-----------------AIAKPWEVQHRIA 637
+ + +GE ++++ L+C ++ D+S ++P +V +
Sbjct: 425 DRLKSGEAG-AVEDERILICQALIKCADISNPVSLIESTVRLSFDTHLQSRPIDVSQHWS 483
Query: 638 KLVADEFFDQGDLEK-LQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPW 696
++ +E+ Q LE+ L L +A D + + Q+GFID PL++ +SD P
Sbjct: 484 SVLLEEWAKQASLEQDLSLPVSVVASADAALQ---AKGQIGFIDLFTKPLFQAVSDALPE 540
Query: 697 MTPLRTGTADNRRRW 711
+ P +N+ W
Sbjct: 541 LQPYADSCMENQTIW 555
>UniRef50_Q7QRM3 Cluster: GLP_481_5888_1773; n=1; Giardia lamblia ATCC
50803|Rep: GLP_481_5888_1773 - Giardia lamblia ATCC 50803
Length = 1371
Score = 69.3 bits (162), Expect = 4e-10
Identities = 57/205 (27%), Positives = 98/205 (47%), Gaps = 16/205 (7%)
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNN 557
++ L LL LCHDL H G +N F TE+ LA+LY+ + +EH H I+ ++
Sbjct: 1131 VDFLALLFGSLCHDLGHTGIDNLFCINTENALALLYNDEAPLEHAHATLSWHII-TQMAV 1189
Query: 558 IFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNG----EFDWQAQEKKELL 613
F+ +P Y++ + IL+TD++ +F + LE +D + + LL
Sbjct: 1190 YFKHFTPCQYREFRALFLEIILATDMSTHFNFLRR-LESLDEDLIIKILEHHNDSEIALL 1248
Query: 614 CGMMMTAC----DVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKD 669
++ C D+S +P E+ R A + +EF+ GDL L+ +P + R +K
Sbjct: 1249 RWYILKVCIKFGDLSNPCRPIEISTRYAVALMNEFWSLGDL-MLECGLEPDKIKTRPQKG 1307
Query: 670 E----LPQMQVGFIDTICLPLYKVL 690
E + Q+GF +I + V+
Sbjct: 1308 EESLIIANSQIGFTQSIVKGFWTVV 1332
>UniRef50_A5DVX9 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 638
Score = 69.3 bits (162), Expect = 4e-10
Identities = 46/175 (26%), Positives = 95/175 (54%), Gaps = 3/175 (1%)
Query: 487 LKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFD 545
L G + ++ ++ L LL++ L HD+ H GT NAF + ++P++++Y+ S +E +H
Sbjct: 366 LNQGGLGCVINPVQSLALLMSALGHDVGHPGTTNAFLMQNKAPISLIYNDRSVLESYHAA 425
Query: 546 QCV-MILNSESNNIFQALSPRDYKDVMH-VVETAILSTDLAMYFKKKSKFLELVDNGEFD 603
+ IL ++ + K ++H VV IL+TD++ +F+ + L ++
Sbjct: 426 VYINQILVVFWPSLLTTKIAEESKLLIHDVVSATILATDMSNHFEYLHQVDSLSKEEDYG 485
Query: 604 WQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQ 658
+ K +LL +++ A D+S +A+P ++ + A ++ EF + LE+L +Q+
Sbjct: 486 PCSDRKIKLLGSLLLKAADISNVARPLKISCQWAVVLQREFDEIKQLEELIQSQR 540
Score = 39.1 bits (87), Expect = 0.49
Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Query: 442 ELVEKFHIPYD-VLCRWILSVKKNYRPVK-YHNWRHALNVAQTMFAMLKTGKMERFMSDL 499
E EK H+P D L I +V++ YR +HN+RHA++V Q F K+ F D
Sbjct: 289 EFAEKLHVPSDNELLAMIFTVRECYRNGNPFHNFRHAVDVLQASFHFCL--KLGHFGDDE 346
Query: 500 EILGLL 505
E +G L
Sbjct: 347 ETIGSL 352
>UniRef50_Q8IKD3 Cluster: Cyclic nucleotide phosphodiesterase,
putative; n=1; Plasmodium falciparum 3D7|Rep: Cyclic
nucleotide phosphodiesterase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 813
Score = 68.5 bits (160), Expect = 7e-10
Identities = 49/226 (21%), Positives = 102/226 (45%), Gaps = 10/226 (4%)
Query: 457 WILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
++L + Y P YHN H V + + ++++ ++ L+A + HD+ H
Sbjct: 443 FLLLINSMYFPNPYHNANHGATVCHLSKCLAHITDYDSYLNNTYMICYLIASIAHDVGHP 502
Query: 517 GTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILN------SESNNIFQALSPRDYKD 569
G N++ ++T L+I Y+ S +E++H IL +N + + +Y +
Sbjct: 503 GKTNSYLSETNHILSIRYNDMSILENYHCSITFSILQLIGFDFLINNEDTKLVEKNNYTN 562
Query: 570 VMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKP 629
+ + I+STD+ ++F+ F + + FD + L + + D+
Sbjct: 563 MRKFIIELIISTDMKLHFEYVDIFKKRKKSQNFDISDTDAIN-LGTINIKLADIGHTCLK 621
Query: 630 WEVQHRIAKLVADEFFDQGDLEKLQLNQ--QPIAMMDREKKDELPQ 673
W+ + LV++EFF Q +E+L N+ P+ + K+D + +
Sbjct: 622 WKDHAKWTMLVSEEFFSQKRVEELHKNKNIDPLNFSNFGKEDNIDE 667
>UniRef50_A2F4K8 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1072
Score = 68.1 bits (159), Expect = 9e-10
Identities = 77/404 (19%), Positives = 154/404 (38%), Gaps = 12/404 (2%)
Query: 320 GVRTLLCMPIVNANKDVIGVAQLINKFTEGDVSIFEAFAIFCGL-GIHNTQMYENACKLM 378
G+ L C P+++ IGV + N DV A C + ++ ++ + C
Sbjct: 675 GITRLCCSPLLSNMSSPIGVVIITNGSIFTDVES-NLLAHLCNIFSLYLQRLIKEKCIEE 733
Query: 379 AKQKVALECLSYHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMF 438
K ++ L A + + ++ Y +F F L D D R F
Sbjct: 734 GPLKSDIDMLISVHERKAYSIPSIIKPTNEQSDEYK--GIRFKAFSLDDADVMRILFFAF 791
Query: 439 LQCELVEKFHIPYDVLCRWILSVKKNY-RPVKYHNWRHALNVAQTMFAMLKTGKMERFMS 497
++ I + + +I ++ V +HN H+L+ Q M + G + + ++
Sbjct: 792 DNLGIMNSLKITAETVYSFISIFNSSFVEGVAFHNKLHSLDCIQFFMFMNQLGTLGQVLN 851
Query: 498 DLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNN 557
+E+ +L + C+ + H GT + + + ++ + + I + E
Sbjct: 852 VVEMHAILASIFCYSMKHDGTTDIYNEHANTINYRVFGPKVLSARARATLLDIYSKE--G 909
Query: 558 IFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMM 617
+ +S D +V T + S D A +K E+V D E + ++ ++
Sbjct: 910 MLGEMSQNDKNYFWNVSTTLLQSIDPADIQPLINKLKEIVKTSLVDLTNTEHRLIIIELI 969
Query: 618 MTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQ--LNQQPIAMMDREKKDELPQMQ 675
A + +P+ + R L A E F G+ E Q + P+ D + P+
Sbjct: 970 FRAAIIGWTVRPFGISSRWQDLRAQESFALGEKENSQGLVYSSPMNSPDLYVR---PKSA 1026
Query: 676 VGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEKVD 719
+ + +PL++ LS F M L +N+ + AE ++
Sbjct: 1027 IDVLVNQSMPLFEALSLAFTEMKSLLDAAVENKNACEAEAEALN 1070
>UniRef50_A2EA57 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1102
Score = 67.7 bits (158), Expect = 1e-09
Identities = 56/264 (21%), Positives = 117/264 (44%), Gaps = 19/264 (7%)
Query: 455 CRWILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLD 514
CR ++++ N +P +HN+RH+++ Q ++ L ++ + +I+GLL A L HD+
Sbjct: 851 CREMINI--NQKP--FHNFRHSVDCLQFVYYTLLKSRLCNKLDPHQIVGLLFATLLHDVS 906
Query: 515 HRGTNNAFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVV 574
H G N+ + ++ L + + ME +H C + ++ I P + +
Sbjct: 907 HNGYNDEYHKNNKTHLYFVDNNYPMETYH---CKV-----ASKIIDEYFPNMNQSFWSMF 958
Query: 575 ETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQH 634
I +T + + S+ + D D+ +C M TA + +E
Sbjct: 959 IPCIKATSILKLVEMSSRIVMKTDEISNDFVF--ISSFVCSMSNTANSF----RTFEFGK 1012
Query: 635 RIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTF 694
+A + E + ++EK + N M+ D + ++ FI T +P + L+ F
Sbjct: 1013 IMANNIFKELTELNEIEKSK-NLPLSNMLPIGSFDNVESLESAFITTTAMPAMRALTTLF 1071
Query: 695 PWMTPLRTGTADNRRRWQDLAEKV 718
P M+ + +N+++W++L +
Sbjct: 1072 PDMSDIYVQLEENKKQWENLKRMI 1095
>UniRef50_Q758Y3 Cluster: ADR395Cp; n=1; Eremothecium gossypii|Rep:
ADR395Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 480
Score = 67.3 bits (157), Expect = 2e-09
Identities = 71/262 (27%), Positives = 121/262 (46%), Gaps = 32/262 (12%)
Query: 469 KYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTES 528
K+ N+RHA++V Q + + K++ +S L L ++ + HD+ H GTNNA K S
Sbjct: 234 KFPNFRHAVDVMQATYQLCDLLKLDPGIS----LTLCISAIGHDVAHPGTNNALMCKYGS 289
Query: 529 PLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYF 587
P+A Y+ S +E+ H D + IL + + +D AI+STD+A++
Sbjct: 290 PVAKHYNGVSVLENFHSDVFISILGQHWPEFSDVVQRQAIRD-------AIISTDMALH- 341
Query: 588 KKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQ 647
+ L+L G +E LL +++ A D+S +++P + + A L++ EF
Sbjct: 342 --EQYLLKLRSCG--TRSLREDIPLLTSLIIKAADISNVSRPLIISAQWAVLISYEFDHC 397
Query: 648 GDLE---KLQLNQQPIAMMD-----REKKDE-------LPQMQVGFIDTICLPLYKVLSD 692
LE K + + + MMD + DE +P Q+ FI T L+ L++
Sbjct: 398 TFLENRLKNEPHNEGEGMMDDLDRVPDSIDEIVSKFPGIPGGQLFFITTFVEGLFAGLAE 457
Query: 693 TFPWMTPLRTGTADNRRRWQDL 714
F + L N+ W L
Sbjct: 458 KFGELKFLSDNVQSNKSFWLQL 479
>UniRef50_A2EE12 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1019
Score = 66.9 bits (156), Expect = 2e-09
Identities = 80/363 (22%), Positives = 164/363 (45%), Gaps = 27/363 (7%)
Query: 293 RSNKSLNISDV--EQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINKFTEGD 350
++NKSL I+D E + D++ G R +L +PI+ A+ IG + NK G+
Sbjct: 614 KNNKSLIINDTFHEAIVHDSS------DRGKRNILLVPII-ADGSQIGCVEACNK--HGN 664
Query: 351 VSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAEDTSKLCQDEIPSA 410
+ + + C I +T + + + + + +S+ + ++ K S
Sbjct: 665 FTQIDLNTLTCISNIVSTSVTMRSMMNVIEHGRSQLIISHFI--NRDEIGKSIVPASFSN 722
Query: 411 ETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKY 470
+T ++ ++ ++ T E+ ++ Q L+ +I D +I SV+ +Y + Y
Sbjct: 723 KT-DINVNEYKAYERTPEELVSTVFEIYHQLNLLG--NIKCDDFFTFICSVRSSYNQLGY 779
Query: 471 HNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPL 530
H+W +++AQ ++ +L + S +EI+ L++A L H GT++++ + +
Sbjct: 780 HSWVKVVSIAQFVYRILSSS--HDVFSKVEIISLIIASLLVYSGHDGTDDSYHKRLMTTE 837
Query: 531 AILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTD-LAMYFK 588
AI+ S S H + + IL+ N +F D +M + + I+S + +A +
Sbjct: 838 AIIAGSRSVHVHLAVTKSMHILSKFKNKLFF----EDVDSIMKSIISFIMSQETIATATE 893
Query: 589 KKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQG 648
+ SK ++D+ +FD + ++L M C A+ E+ + L + E F G
Sbjct: 894 ELSK---VIDSHQFDITCETHRQLFLQCMFNMCLYDEFARSNEISDKWEYLYSLERFSLG 950
Query: 649 DLE 651
E
Sbjct: 951 TRE 953
Score = 43.6 bits (98), Expect = 0.023
Identities = 20/39 (51%), Positives = 24/39 (61%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
FN ID TGY T ++ PI N G+V GV Q+INK D
Sbjct: 468 FNPSIDEMTGYTTRTLMSTPIINTFGEVHGVIQLINKMD 506
Score = 41.5 bits (93), Expect = 0.093
Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 5/99 (5%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA++ + LN+S+ N RTL+ PI+N +V GV QLINK
Sbjct: 446 IAGYVAQTGQELNLSNAADSSHFNPSIDEMTGYTTRTLMSTPIINTFGEVHGVIQLINKM 505
Query: 346 ----FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAK 380
F++ D I + C IHN + + L +
Sbjct: 506 DNMPFSKRDSLIATVYGTLCTYMIHNQNLQDQTNDLQKR 544
>UniRef50_Q7RXW7 Cluster: Putative uncharacterized protein
NCU00478.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00478.1 - Neurospora crassa
Length = 806
Score = 66.5 bits (155), Expect = 3e-09
Identities = 73/312 (23%), Positives = 132/312 (42%), Gaps = 39/312 (12%)
Query: 416 YSFQFHDFDLTDEDTCRA--TLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRP-VKYHN 472
+ F H FD DE A TL L ++ F I L ++ + + Y V YHN
Sbjct: 249 WHFDAHKFDY-DELIVAAELTLNHALSMPELKAFRISPTQLQNFLKACRAAYMGFVPYHN 307
Query: 473 WRHALNVAQTMFA-MLKTGKMERF-------------------MSDLEILGLLVACLCHD 512
+RH ++V Q F +L+ G + + + E LL+ + HD
Sbjct: 308 FRHVVDVLQATFQQLLRIGALPPYPNVNGTHTSPIAESPGTPSIGPEEAFTLLLTAIGHD 367
Query: 513 LDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVM 571
+ H G NN F + +PLA LY+ S +E+ H IL + + + +
Sbjct: 368 VLHPGVNNGFLIEARAPLAELYNDRSVLENFHSTSYCQILKRHWPIFY------ENRRLR 421
Query: 572 HVVETAILSTDLAMYFKKKSKFLEL----VDNGEFD-WQ---AQEKKELLCGMMMTACDV 623
++ + IL+TD+A++F +K L + D W E + L+C +++ D+
Sbjct: 422 TLMISCILATDMALHFDYMAKLGNLQKLQAQKPDLDGWNEKAVDEARVLVCALIIKCADI 481
Query: 624 SAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTIC 683
S +A+ ++ + L+ DE Q +E + + D + Q+ F++
Sbjct: 482 SNVARRHDIGAQWMHLLNDELILQTQIEMDMGQKTALIAPPSTSLDGRIRSQLKFMELFA 541
Query: 684 LPLYKVLSDTFP 695
PL++ ++D P
Sbjct: 542 FPLFRGVADILP 553
>UniRef50_A4RPY9 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 862
Score = 66.5 bits (155), Expect = 3e-09
Identities = 67/251 (26%), Positives = 108/251 (43%), Gaps = 40/251 (15%)
Query: 410 AETYNLYSFQFHDFDLTDEDTCRATLRM--FLQCELVEKFHIPYDVLCRWILSVKKNYRP 467
A+ + + F HDF DE ATL + L +E++ + D L ++++ + Y
Sbjct: 302 AKAVSRWHFCAHDFS-DDELIVAATLMLKHALAMPELERWRMSTDQLSTFLIACRAAYNN 360
Query: 468 -VKYHNWRHALNVAQTMFAML---------------------KTGKMERFMSDLEILGLL 505
V YHN+RH ++V Q F L T + M E L LL
Sbjct: 361 FVPYHNFRHVIDVLQATFNFLVQIGSLPPFPPRSDDYIATPQPTSPIATLMKPFEALTLL 420
Query: 506 VACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQALSP 564
V + HD+ H G NN F +PLA LY+ S +E H IL F+ L
Sbjct: 421 VTAVGHDVGHPGVNNGFLVTLNAPLAQLYNDRSVLESFHCAAYSQILRRYWPAAFEDLQM 480
Query: 565 RDYKDVMHVVETAILSTDLAMYFKKKSKFLELVD-----NGEFDWQA---QEKKELLCGM 616
R +++ ++IL+TD+ ++F K +L + N W +E K L C +
Sbjct: 481 R------NLMISSILATDMGLHFDYMKKLGDLQEKLHENNAIEGWNGRVIEEHKALACAI 534
Query: 617 MMTACDVSAIA 627
++ D+S ++
Sbjct: 535 LIKCADISNVS 545
>UniRef50_A5K353 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 803
Score = 66.1 bits (154), Expect = 4e-09
Identities = 45/204 (22%), Positives = 91/204 (44%), Gaps = 8/204 (3%)
Query: 457 WILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
++L + Y P YHN H V + ++ +++ ++ L+A + HD+ H
Sbjct: 422 FLLLINNMYFPNPYHNANHGATVCHLSKCLAHITDFDKSLNNTYMICYLIASIAHDVGHP 481
Query: 517 GTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIF------QALSPRDYKD 569
G NA+ ++T L+I Y+ S +E++H IL ++ + + Y +
Sbjct: 482 GKTNAYLSETNHILSIRYNDMSILENYHCSITFSILQLIGHDFLINSEDTKLVEKNSYAN 541
Query: 570 VMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKP 629
+ + I+STD+ ++F+ F + + FD ++ L + + D+
Sbjct: 542 LRKFIIELIISTDMKLHFEYVDIFKKRKRSENFDISDRDAIN-LGTINIKVADIGHTCLK 600
Query: 630 WEVQHRIAKLVADEFFDQGDLEKL 653
W + LV++EFF Q +E+L
Sbjct: 601 WRDHAKWTMLVSEEFFSQKKVEEL 624
>UniRef50_A2FSQ8 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 1017
Score = 65.7 bits (153), Expect = 5e-09
Identities = 33/148 (22%), Positives = 76/148 (51%), Gaps = 4/148 (2%)
Query: 422 DFDLTDE-DTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNWRHALNVA 480
DFD +E ++ ++F + +++ + R++ S K+++ YHNW HA++
Sbjct: 749 DFDARNEIESITVPYQIFQKMGILQFLGVDDQSFYRFLESCMKSHKNYPYHNWSHAVDTL 808
Query: 481 QTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-STSTM 539
Q ++ + + ++ +L+ L ++ LCHD+ H G ++ + +S A+L+ + S M
Sbjct: 809 QFLYYLYYRANLTKYFDELQKTCLFISALCHDVSHNGFSSYYHVSAQSRTALLFGNESPM 868
Query: 540 EHHHFDQCVMILNSESNNIFQALSPRDY 567
E F + +L E ++ F+ + ++
Sbjct: 869 EILSFSKTAELL--EKSDFFEKVDKPEF 894
>UniRef50_UPI00006CD10E Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 516
Score = 65.3 bits (152), Expect = 7e-09
Identities = 33/140 (23%), Positives = 66/140 (47%), Gaps = 1/140 (0%)
Query: 405 DEIPSAETYNLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKN 464
D + + + F F+ T+++ +MF + K++I L + + N
Sbjct: 165 DRMNKFDISKVLDFNFNMHLYTNKELVDIAFQMFEYANIHTKYNIDDSFLKDLLEEMCMN 224
Query: 465 YRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQT 524
Y + YHNW HA ++Q F + T + + E L++ L HD++H+G NN ++
Sbjct: 225 YNVIPYHNWTHAFQLSQMFFTVYFTSDFKDLIDSFEFFVGLLSGLAHDMNHKGVNNLYKV 284
Query: 525 KTESPLAILY-STSTMEHHH 543
K ++ ++ Y + +E+ H
Sbjct: 285 KRKAENSLRYMEQAVLENMH 304
>UniRef50_Q5C3V6 Cluster: SJCHGC08281 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC08281 protein - Schistosoma
japonicum (Blood fluke)
Length = 152
Score = 65.3 bits (152), Expect = 7e-09
Identities = 31/67 (46%), Positives = 42/67 (62%)
Query: 650 LEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRR 709
LEK QL P A+MDRE+ +ELP++QV FID+IC+P+Y+ + PL G NR
Sbjct: 1 LEKEQLKLTPTALMDRERCNELPKLQVSFIDSICMPIYEAIVQVSSNFEPLLKGCKRNRT 60
Query: 710 RWQDLAE 716
W L+E
Sbjct: 61 CWLILSE 67
>UniRef50_Q6BSL2 Cluster: Similar to tr|O94034 Candida albicans
Nucleotide phosphodiesterase; n=2;
Saccharomycetaceae|Rep: Similar to tr|O94034 Candida
albicans Nucleotide phosphodiesterase - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 611
Score = 64.1 bits (149), Expect = 2e-08
Identities = 53/232 (22%), Positives = 106/232 (45%), Gaps = 18/232 (7%)
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCV-MILNS 553
M+ ++ L LL+A L HD+ H G NAF K +P++++Y+ S +E +H + IL
Sbjct: 379 MNSIQTLALLIAALGHDVGHPGVTNAFMIKHSAPMSLIYNERSVLELYHSAVFINKILAI 438
Query: 554 ESNNIFQALSPRDYK-DVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKEL 612
I R K + +++ + IL+TD+A +F+ K + + L
Sbjct: 439 NWPGILSVNIDRKTKISLKNLIISCILATDMAEHFEYIDKLAHF--KADRYMLEVNRVNL 496
Query: 613 LCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEK------------LQLNQQPI 660
+ +++ D+S + +P V + A ++ EF + LEK + ++ P
Sbjct: 497 ISSLLIKCADISNVTRPLRVSSQWALVLGREFCEVSTLEKKLAHNQLTPELDIHYDKVPS 556
Query: 661 AMMD-REKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRW 711
A+ D + ++ + Q+ FI+T L+ +++ P + +N+ W
Sbjct: 557 ALPDILQANPDIHKGQIFFINTFAENLFNNIAELLPELRYTCDIVQENKEFW 608
>UniRef50_A2DCH1 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1106
Score = 63.3 bits (147), Expect = 3e-08
Identities = 53/245 (21%), Positives = 112/245 (45%), Gaps = 13/245 (5%)
Query: 470 YHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESP 529
+H++ H+++V M K+ + + +E L L +A + HD H G N K +P
Sbjct: 873 FHDYHHSIDVLTQCIQMCKSS-YGQVLLPIERLSLYIAAISHDSLHDGFVNL---KLGTP 928
Query: 530 LAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYK-DVMHVVETAILSTDLAMYFK 588
L S ME D +S F+ L+ +D K +++ IL+TD++ +F
Sbjct: 929 YECLLKFSPMEMRSVD-----FLRQSVEKFEFLTEKDAKNELLSEASRFILATDMSKHFD 983
Query: 589 KKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQG 648
+ +L D+ F ++ +E + +++ + D+ + + + + K + DEFF +G
Sbjct: 984 LIEEAKKLADSDNFSFEDKETRMKTTEILIKSADLGSANRNGDKADK--KGLPDEFFAEG 1041
Query: 649 DLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNR 708
DL K++ +R K ++ F++ + +P ++ L+ P + + +N
Sbjct: 1042 DLSKVKDIVYDKEGNER-KNIHWGDSEIPFMNDVLVPTFETLAMLLPDLEDMLKQVKENV 1100
Query: 709 RRWQD 713
+W +
Sbjct: 1101 EKWSN 1105
>UniRef50_Q5C1P7 Cluster: SJCHGC07646 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07646 protein - Schistosoma
japonicum (Blood fluke)
Length = 219
Score = 62.1 bits (144), Expect = 6e-08
Identities = 31/100 (31%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
Query: 497 SDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCV-MILNSE 554
++++ + L+A + HD+DH G N F + PLAILY+ + +E HH + L S
Sbjct: 12 TNIDEVATLLAAIVHDVDHPGKTNPFLVNSNDPLAILYNDIAVLESHHAAVAFELTLRSP 71
Query: 555 SNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFL 594
NIFQ L+ +Y+ + + +L+T++ +F +KF+
Sbjct: 72 DINIFQNLTREEYRTMRSYIVDMVLATEMVRHFDIVTKFV 111
>UniRef50_UPI00006A17C5 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).;
n=1; Xenopus tropicalis|Rep: cGMP-inhibited 3',5'-cyclic
phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1). -
Xenopus tropicalis
Length = 959
Score = 61.7 bits (143), Expect = 8e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 499 LEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQC-VMILNSESN 556
LE++ L VA HD DH G NAF T +P A+LY+ S +E+HH + L+ +
Sbjct: 703 LELMALFVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLFLSQPEH 762
Query: 557 NIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF 593
N L +K +V AIL+TDL +F ++F
Sbjct: 763 NFLTYLDHVQFKRFRFLVIEAILATDLKKHFDFLAEF 799
>UniRef50_Q4SV96 Cluster: Chromosome 10 SCAF13771, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF13771, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 816
Score = 60.9 bits (141), Expect = 1e-07
Identities = 36/106 (33%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Query: 490 GKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQC- 547
G + + LE++ L VA HD DH G NAF T +P A+LY+ S +E+HH
Sbjct: 460 GSLAGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQALLYNDRSVLENHHAASAW 519
Query: 548 VMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF 593
+ L+ N L ++K +V AIL+TDL +F ++F
Sbjct: 520 NLFLSRPEYNFLVNLEHVEFKRFRFLVIEAILATDLKKHFDFLAEF 565
Score = 39.5 bits (88), Expect = 0.37
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 603 DWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAM 662
DW + + L+C M + DV+ K E+ + + + +EF+ QGD E+ L
Sbjct: 620 DWTNENDRLLVCQMCIKLADVNGPLKCKELHLQWTEGIVNEFYQQGD-EEASLGLPISPF 678
Query: 663 MDREKKDELPQMQVGFIDTICLPL 686
MDR +L ++Q FI I PL
Sbjct: 679 MDR-SAPQLAKLQESFITHIVGPL 701
>UniRef50_A2DVK5 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 771
Score = 60.9 bits (141), Expect = 1e-07
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
Query: 292 ARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----FT 347
A S LNI D + R N + + +TLLC+PI++ + ++ GV ++INK F+
Sbjct: 492 AMSQSILNIRDAYEDPRFNRNTDKQTGYRTKTLLCVPIIDDHGNIQGVTEMINKMDGHFS 551
Query: 348 EGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASAE 397
D + E F +FC L I N ++Y + +L + K +E +S T ++E
Sbjct: 552 SDDEQMMEVFNVFCALSIENAKLYNASIELTMQLKSIME-ISQTLTRTSE 600
Score = 50.8 bits (116), Expect = 2e-04
Identities = 19/46 (41%), Positives = 33/46 (71%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
+FN D +TGY+T+ +LC+PI + G++ GV ++INK DG +++
Sbjct: 508 RFNRNTDKQTGYRTKTLLCVPIIDDHGNIQGVTEMINKMDGHFSSD 553
Score = 36.3 bits (80), Expect = 3.5
Identities = 17/82 (20%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
FSS D ++ + FC + I+NA+L+ +S+ + + ++ +++++ S + +V I
Sbjct: 550 FSSDDEQMMEVFNVFCALSIENAKLYNASIELTMQLKSIMEISQTL-TRTSEMHSVVDNI 608
Query: 210 MTEARDLLKCERCAVFILDTDH 231
+ + R ++ R ++ + D+
Sbjct: 609 LKDTRKVIGAGRALLYSVKGDN 630
>UniRef50_Q7A2D9 Cluster: Adenylate cyclase; n=6; Cyanobacteria|Rep:
Adenylate cyclase - Anabaena sp. (strain PCC 7120)
Length = 859
Score = 60.5 bits (140), Expect = 2e-07
Identities = 36/103 (34%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----F 346
VA + +LNISD + R + + + R +LC+P+ N+ ++IGV QLINK F
Sbjct: 297 VASTGDALNISDAYKDPRFDPTTDRKTGYLTRNILCLPVFNSANELIGVTQLINKQQGSF 356
Query: 347 TEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLS 389
T D AF I G+ + N +++EN QK L+ LS
Sbjct: 357 TASDEEFMRAFNIQAGVALENARLFENVLLEKQYQKDILQSLS 399
Score = 47.2 bits (107), Expect = 0.002
Identities = 19/44 (43%), Positives = 28/44 (63%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHT 98
+F+ D +TGY T ILC+P+ N +++GV Q+INK G T
Sbjct: 314 RFDPTTDRKTGYLTRNILCLPVFNSANELIGVTQLINKQQGSFT 357
Score = 42.3 bits (95), Expect = 0.053
Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 8/68 (11%)
Query: 34 MHTPIPGKIP-HKLTAIKYITIQ-------FNSEIDARTGYKTELILCMPICNYEGDVVG 85
+ TPI IP H + +Y+ I F+ E++ + GYK ILCMP+ + + +V
Sbjct: 114 IRTPITVGIPGHVASTGQYLNISETATHPLFSPELERQMGYKINNILCMPVVSSKDQIVA 173
Query: 86 VAQIINKT 93
V Q+ NKT
Sbjct: 174 VVQLANKT 181
Score = 37.1 bits (82), Expect = 2.0
Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 5/91 (5%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----- 345
VA + + LNIS+ + + + +LCMP+V++ ++ V QL NK
Sbjct: 126 VASTGQYLNISETATHPLFSPELERQMGYKINNILCMPVVSSKDQIVAVVQLANKTGNIP 185
Query: 346 FTEGDVSIFEAFAIFCGLGIHNTQMYENACK 376
F D F FA G+ + Q + A +
Sbjct: 186 FNRNDEESFRDFAASIGIILETCQSFYVAAR 216
>UniRef50_UPI0000660DD6 Cluster: Homolog of Homo sapiens
"Phosphodiesterase PDE9A5; n=1; Takifugu rubripes|Rep:
Homolog of Homo sapiens "Phosphodiesterase PDE9A5 -
Takifugu rubripes
Length = 305
Score = 59.7 bits (138), Expect = 3e-07
Identities = 37/116 (31%), Positives = 63/116 (54%), Gaps = 6/116 (5%)
Query: 576 TAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHR 635
T IL+TD+A + + F + VD FD+ ++ L +++ CD+S +P EV
Sbjct: 4 TLILATDMARHGEILDSFKQKVDG--FDFADEDHMTCLKMVLIKCCDISNEVRPMEVAEP 61
Query: 636 IAKLVADEFFDQGDLEKLQLNQQPIA-MMDREKKDELPQMQVGFIDTICLPLYKVL 690
+ +E+F Q D EK + P+A MDREK + P Q+GFI + +P+++ +
Sbjct: 62 WVDCLLEEYFMQSDREKTE--GLPVAPFMDREKVTK-PTAQIGFIKFVLIPMFETV 114
>UniRef50_UPI000065CC62 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase A) (CGI-PDE A).; n=1; Takifugu
rubripes|Rep: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase A) (CGI-PDE A). - Takifugu rubripes
Length = 706
Score = 59.3 bits (137), Expect = 4e-07
Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Query: 490 GKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQC- 547
G + + LE++ L VA HD DH G NAF T +P A+LY+ S +E+HH
Sbjct: 376 GCLSGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAW 435
Query: 548 VMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF 593
+ ++ N L ++K +V AIL+TDL +F ++F
Sbjct: 436 NLFMSHPEYNFLVNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEF 481
Score = 37.1 bits (82), Expect = 2.0
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 603 DWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAM 662
DW + + L+C M + DV+ K ++ + + + +EF+ QGD E+ +
Sbjct: 526 DWSNENDRLLVCQMCIKLADVNGPLKCKDLHLQWTEGIVNEFYQQGD-EESSMGLPISPF 584
Query: 663 MDREKKDELPQMQVGFIDTICLPL 686
MDR +L ++Q FI I PL
Sbjct: 585 MDR-AAPQLAKLQESFITHIVGPL 607
>UniRef50_A2FCG3 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 647
Score = 59.3 bits (137), Expect = 4e-07
Identities = 33/91 (36%), Positives = 50/91 (54%), Gaps = 6/91 (6%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA + + LNI D + R N +++LC+PI+ + VIGV Q+INK
Sbjct: 556 IAGHVATTGQLLNIPDAYEDPRFNKDVDLSTGYRTKSILCVPIIGRAEQVIGVTQMINKT 615
Query: 346 -----FTEGDVSIFEAFAIFCGLGIHNTQMY 371
FT GDV + +AF +FCG+ + N + +
Sbjct: 616 GEATQFTPGDVDLMKAFNVFCGIALSNAKSF 646
Score = 50.4 bits (115), Expect = 2e-04
Identities = 23/44 (52%), Positives = 31/44 (70%), Gaps = 1/44 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHT 98
+FN ++D TGY+T+ ILC+PI V+GV Q+INKT GE T
Sbjct: 577 RFNKDVDLSTGYRTKSILCVPIIGRAEQVIGVTQMINKT-GEAT 619
>UniRef50_Q6CY30 Cluster: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P06776
Saccharomyces cerevisiae YOR360c PDE2 high affinity 3 -
Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 516
Score = 58.4 bits (135), Expect = 8e-07
Identities = 47/185 (25%), Positives = 91/185 (49%), Gaps = 23/185 (12%)
Query: 469 KYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTES 528
K+HN+RHA++V Q + + ++ + S L L +A + HD+ H GTNN K S
Sbjct: 265 KFHNFRHAVDVLQATYQLCHLLELPKLASFL----LCIAAIGHDVAHPGTNNMLFNKYVS 320
Query: 529 PLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYF 587
P++ Y S +E+ H D + IL+ + Q + ++ +I++TD+A++
Sbjct: 321 PISKYYKEQSVLENFHADIYLDILSHYWPELSQEFTG---------IKDSIIATDMALH- 370
Query: 588 KKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQ 647
+ ++E + + L +++ A D+S + +P + + A L++ EF +
Sbjct: 371 ---NHYVETIKQ-----ETGPNLTGLTSLIIKAADISNVTRPLLISAKWAALISMEFKEC 422
Query: 648 GDLEK 652
LEK
Sbjct: 423 AVLEK 427
>UniRef50_P06776 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase
2; n=2; Saccharomyces cerevisiae|Rep:
3',5'-cyclic-nucleotide phosphodiesterase 2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 526
Score = 58.4 bits (135), Expect = 8e-07
Identities = 52/204 (25%), Positives = 98/204 (48%), Gaps = 19/204 (9%)
Query: 458 ILSVKKNYRPV-KYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
+ +++ +Y V K+HN+RHA++V Q + + + + ++ L L +A + HD+ H
Sbjct: 251 LFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKD---NPVQTLLLCMAAIGHDVGHP 307
Query: 517 GTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVE 575
GTNN ES +A + + S +E+ H + +L S + Q LS K +
Sbjct: 308 GTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLL---SEHWPQLLSIS--KKKFDFIS 362
Query: 576 TAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHR 635
AIL+TD+A++ + + + + + K+ L +++ A D+S + + + R
Sbjct: 363 EAILATDMALHSQYEDRLMH---------ENPMKQITLISLIIKAADISNVTRTLSISAR 413
Query: 636 IAKLVADEFFDQGDLEKLQLNQQP 659
A L+ EF D LE +P
Sbjct: 414 WAYLITLEFNDCALLETFHKAHRP 437
>UniRef50_Q29FT2 Cluster: GA17041-PA; n=1; Drosophila
pseudoobscura|Rep: GA17041-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 815
Score = 57.2 bits (132), Expect = 2e-06
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 4/123 (3%)
Query: 578 ILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIA 637
IL+TD+A + + ++F+E+ FD+ + LLC +++ D+S A+P +V
Sbjct: 33 ILATDMARHNEILTQFMEITPI--FDYSNRAHINLLCMILIKVADISNEARPMDVAEPWL 90
Query: 638 KLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLSDTFPWM 697
+ EFF Q EK + MD +K + P QV FI + LPL++ L + P +
Sbjct: 91 DRLLQEFFAQSAAEKSE-GLPVTPFMDPDKVSK-PGSQVRFIGLVLLPLFEALGELVPEL 148
Query: 698 TPL 700
T L
Sbjct: 149 TEL 151
>UniRef50_O94034 Cluster: Nucleotide phosphodiesterase; n=4;
Saccharomycetales|Rep: Nucleotide phosphodiesterase -
Candida albicans (Yeast)
Length = 571
Score = 56.8 bits (131), Expect = 2e-06
Identities = 50/239 (20%), Positives = 108/239 (45%), Gaps = 18/239 (7%)
Query: 496 MSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCV--MILN 552
++ ++ LGLLVA L HD+ H GT N F K +P A+LY+ S +E +H + ++
Sbjct: 334 LNPIQTLGLLVAALGHDVGHPGTTNDFMIKFSAPTALLYNDRSVLESYHASLFINKVLRI 393
Query: 553 SESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKEL 612
+ + + + + ++ ++IL+TD+ + + ++ + E +L
Sbjct: 394 CWPDLLTCTIEEKSELTIRSLIISSILATDMGEHNEYVNRLKSFKTHNEI-LNHDNTVKL 452
Query: 613 LCGMMMTACDVSAIAKPWEVQHRIAKLVADEF-------------FDQGDLEKLQLNQQP 659
+ +++ D+S + +P V + A +++ EF D + L + P
Sbjct: 453 ISALLIKCADISNVTRPLRVSAQWAMVLSREFAEVELLKSVIKKDIDLDFTKDLTYDHVP 512
Query: 660 IAMMD-REKKDELPQMQVGFIDTICLPLYKVLSDTFPWMTPLRTGTADNRRRWQDLAEK 717
+ + E + ++ + Q+ FI+ L+ +SD P + +N+ W + A+K
Sbjct: 513 HELREILEIQPDIHKGQIFFINLFAENLFNSVSDLLPQLQYTCDIIMENKLFWLERAKK 571
Score = 35.9 bits (79), Expect = 4.6
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 416 YSFQFHDFDLTDEDTCRATLRMFLQCELVEKF-HIPYDVLCRWILSVKKNYRPVK-YHNW 473
+SF H+ D C L + + VE F +IP + L +I V+ Y+ +HN+
Sbjct: 218 WSFPAHNLSNDDLVYC-VYLMIDYAIKQVEGFDNIPLNELLAFIFIVRDTYKNGNPFHNF 276
Query: 474 RHALNVAQTMF-AMLKTGKMERFMSDLE 500
RHA++V Q F +++ G + +F +E
Sbjct: 277 RHAVDVLQACFHFLIRLGSLPKFKQFVE 304
>UniRef50_UPI0001555C30 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein, partial - Ornithorhynchus anatinus
Length = 319
Score = 55.6 bits (128), Expect = 5e-06
Identities = 40/126 (31%), Positives = 65/126 (51%), Gaps = 9/126 (7%)
Query: 568 KDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELLCGMMMTACDVSAIA 627
+++ +V +LSTD++ +F++ + E + + K L +++ A D+S
Sbjct: 77 RELRSLVIEMVLSTDMSCHFQQVKSMKTSLQQLE---RIDKSKAL--SLLLHAADISHPT 131
Query: 628 KPWEVQHRIAKLVADEFFDQGDLE-KLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPL 686
K W V R K + +EFF QGD E +L L P+ DR + Q Q+GFID I P
Sbjct: 132 KQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLC--DR-TSTLVAQSQIGFIDFIVEPT 188
Query: 687 YKVLSD 692
+ VL+D
Sbjct: 189 FSVLTD 194
>UniRef50_Q4FXD4 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major strain Friedlin
Length = 1084
Score = 54.8 bits (126), Expect = 9e-06
Identities = 55/256 (21%), Positives = 114/256 (44%), Gaps = 12/256 (4%)
Query: 454 LCRW---ILSVKKNYRPVKYHNWRHALNVAQTMFAML-KTGKMERFMSDLEILGLLVACL 509
L RW + +V+ NYR +YHN HA +V Q ++AM+ + M+ +E ++ A
Sbjct: 592 LHRWACLLATVQANYRANQYHNRVHAADVLQGVYAMICSCPGLLPHMTTVEKRAVVFAAA 651
Query: 510 CHDLDHRGTNNAFQTKTESPLAILYS-TSTMEHHHFDQCVMILNSESNNIFQA-LSPRDY 567
HD+ H G + F T + Y+ +E H +L + + + + +
Sbjct: 652 VHDIRHPGRSEVFLKNTFDATYVHYNGLQVLEQMHTATAFHLLATPELDFTRGNMDDTEA 711
Query: 568 KDVMHVVETAILSTDLAMYFKKKSKFLELVDNGE-FDWQAQEKKELLCGMMMTACDVSAI 626
+ +V I T + + ++ + +G+ +D ++ + + + A D+ A
Sbjct: 712 LEFHGLVAALIGCTFMGRHASLMEQWSRPLQDGKTYDMAVTADRQQVLSLFLHAADIGAQ 771
Query: 627 AKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPL 686
A+ V + +V +E QGD E + P++ + L + Q+ F++ +PL
Sbjct: 772 ARGLTVARKWLGIV-EEMRAQGDDEAAR--GLPLS-PGSSRSASLERGQIFFMEMFVVPL 827
Query: 687 YKVLSDTFPWM-TPLR 701
+ ++ FP + +P+R
Sbjct: 828 FDLVHQMFPSIESPMR 843
>UniRef50_A3WDP1 Cluster: Adenylate/Guanylate Cyclase; n=1;
Erythrobacter sp. NAP1|Rep: Adenylate/Guanylate Cyclase
- Erythrobacter sp. NAP1
Length = 767
Score = 52.4 bits (120), Expect = 5e-05
Identities = 22/46 (47%), Positives = 31/46 (67%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
Y +FN ++DA+TG+ T IL PI N G+ +GVAQ++NK GE
Sbjct: 114 YTDPRFNKDVDAQTGFTTTSILASPIRNARGETIGVAQVLNKVAGE 159
Score = 52.4 bits (120), Expect = 5e-05
Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA +V S +++NI LR N ++ R++LC+P+VN + + IGV Q++NK
Sbjct: 264 IAGSVFTSGEAINIPHAYTDLRFNPAFDKQSGFFTRSILCVPVVNKSGETIGVTQVLNKR 323
Query: 346 ---FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHA-TASAEDTSK 401
F E D S +AF +G+ N +++ + + + L+ +S T E ++
Sbjct: 324 GGPFNEEDESRLKAFTAQIAIGLENAKLFADIQSMKNYNESMLQSMSNGVITFDEEGANR 383
Query: 402 LC 403
C
Sbjct: 384 TC 385
Score = 49.6 bits (113), Expect = 3e-04
Identities = 19/50 (38%), Positives = 30/50 (60%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
Y ++FN D ++G+ T ILC+P+ N G+ +GV Q++NK G E
Sbjct: 281 YTDLRFNPAFDKQSGFFTRSILCVPVVNKSGETIGVTQVLNKRGGPFNEE 330
Score = 41.9 bits (94), Expect = 0.070
Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 149 EFSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTK 208
EF+ +D++V + C I +++ QL E + + +R +I S + L L+ +
Sbjct: 159 EFNEQDLQVLEGITSQCAITLESMQLVER-MEDSRRREIEFLNIVSEMTSELELTTLLRR 217
Query: 209 IMTEARDLLKCERCAVFILDTDHCE 233
+MTEA +L ER +FI D E
Sbjct: 218 VMTEATSMLDAERSTLFINDEKTAE 242
Score = 41.1 bits (92), Expect = 0.12
Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
Query: 275 GAPRRPHDALPAIALA--VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNA 332
G RR L I +A +S + L I D R N + ++L PI NA
Sbjct: 83 GMKRREIRILDTIGIAGTTFQSGEGLIIHDPYTDPRFNKDVDAQTGFTTTSILASPIRNA 142
Query: 333 NKDVIGVAQLINK----FTEGDVSIFEAFAIFCGLGIHNTQMYE 372
+ IGVAQ++NK F E D+ + E C + + + Q+ E
Sbjct: 143 RGETIGVAQVLNKVAGEFNEQDLQVLEGITSQCAITLESMQLVE 186
>UniRef50_A2FYJ6 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 902
Score = 51.6 bits (118), Expect = 9e-05
Identities = 53/281 (18%), Positives = 124/281 (44%), Gaps = 31/281 (11%)
Query: 414 NLYSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVKKNYRPVKYHNW 473
N++ + F +L ++ + ++F + + + F++ L ++ +K
Sbjct: 631 NVFKYTFQTNNLKIQNYYQLVFKIFGRFRIFDNFNVSNAALFNFLREIKLT--------- 681
Query: 474 RHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAIL 533
+ + Q ++L +ME +S++E+ G LV+C+ D + N+ ESP AI+
Sbjct: 682 KQGADNLQMFASLLLQCRMESTLSNMELFGSLVSCILSD--YNCPQNSILV--ESPEAIV 737
Query: 534 YSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKF 593
+ V ++ ++ NNIF+++ D K++ ++ ++S+D ++ +
Sbjct: 738 ---------SLSKAVTVMANDGNNIFKSIQQTDLKNIWDLIIDLVVSSDFNNFYNVLNSA 788
Query: 594 LELVD---NGEFDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDL 650
+++D + E D Q K+ + + +S + + +I+ L D FF + DL
Sbjct: 789 EKVIDGENDDEDDNQKYSMKKENLKLFLACAKLSPCVRNKKGDEKISNLATD-FFRRCDL 847
Query: 651 EKLQLNQQPIAMMDREKKDELPQMQVGFIDTICLPLYKVLS 691
+ RE+ D+ ++ + +P +K+LS
Sbjct: 848 THTSFKD----VKSREEIDQ-EKISDALFNDAAIPAFKLLS 883
>UniRef50_Q6FM93 Cluster: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3; n=1; Candida
glabrata|Rep: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3 - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 575
Score = 49.6 bits (113), Expect = 3e-04
Identities = 28/90 (31%), Positives = 52/90 (57%), Gaps = 4/90 (4%)
Query: 458 ILSVKKNYRPV-KYHNWRHALNVAQTMFAMLKT--GKMERFMSDLEILGLLVACLCHDLD 514
+++++ +Y + K+HN+RHA++V Q + + G +S L +L L ++ + HD+
Sbjct: 240 LITIEASYHQINKFHNFRHAVDVMQATWQICSNLGGNGSIDLSPLTVLLLSMSAIGHDIG 299
Query: 515 HRGTNNAFQTKTESPLAILY-STSTMEHHH 543
H GTNN + ES LA + + S +E+ H
Sbjct: 300 HPGTNNQLLCQHESFLATNFDNKSVLENFH 329
Score = 41.1 bits (92), Expect = 0.12
Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 5/99 (5%)
Query: 554 ESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFKKKSKFLELVDNGEFDWQAQEKKELL 613
+SNNI + D K ++V+ AIL+TD+AM+ K K EL+ Q L
Sbjct: 370 KSNNINEN-DDNDKKMTINVITNAILATDMAMHAKYVDKLDELLKVP----QHLLPLPTL 424
Query: 614 CGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEK 652
+++ A D+S + +P + R A L+ EF D L+K
Sbjct: 425 IAVIIKAADISNVTRPLSISARWAFLITLEFNDCSLLDK 463
>UniRef50_A0LGQ1 Cluster: Putative PAS/PAC sensor protein; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Putative PAS/PAC
sensor protein - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 535
Score = 48.8 bits (111), Expect = 6e-04
Identities = 21/53 (39%), Positives = 31/53 (58%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTL 103
Y +FN E+D +TGYKT +L +PI + +VGV Q++NK G + L
Sbjct: 133 YADARFNPEMDKKTGYKTRNVLAVPIKTKDRQIVGVIQLLNKKSGSFSENDLL 185
Score = 40.7 bits (91), Expect = 0.16
Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 294 SNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----FTEG 349
+ + +NI D R N + R +L +PI ++ ++GV QL+NK F+E
Sbjct: 123 TGQPVNIDDAYADARFNPEMDKKTGYKTRNVLAVPIKTKDRQIVGVIQLLNKKSGSFSEN 182
Query: 350 DVSIFEAFAIFCGLGIHNTQMYE 372
D+ + EA + N Q YE
Sbjct: 183 DLLMLEAIGGQAAAALQNAQTYE 205
Score = 37.5 bits (83), Expect = 1.5
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 323 TLLCMPIVNANKDVIGVAQLINK----FTEGDVSIFEAFAIFCGLGIHNTQMYENACK 376
++LC PI + V+GV Q+ NK F D S E FA + + I N +++E K
Sbjct: 333 SVLCAPIKTSQGKVVGVIQVRNKKGGPFDRADESRLEIFAGYASIAIRNAELFEATLK 390
Score = 36.3 bits (80), Expect = 3.5
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 60 IDARTGYKTELILCMPICNYEGDVVGVAQIINKTDG--EHTTESTLD 104
+D G+ +LC PI +G VVGV Q+ NK G + ES L+
Sbjct: 323 VDIEPGFPAHSVLCAPIKTSQGKVVGVIQVRNKKGGPFDRADESRLE 369
>UniRef50_A0YPV9 Cluster: Adenylate/Guanylate Cyclase; n=1; Lyngbya
sp. PCC 8106|Rep: Adenylate/Guanylate Cyclase - Lyngbya
sp. PCC 8106
Length = 1159
Score = 48.4 bits (110), Expect = 8e-04
Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 38 IPGKIPHKLTAIKYITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
IP IP L Y + D +TGY+T +LCMP+ N +GD++GV Q+INK
Sbjct: 1045 IPLNIPFDL--YDYPDSETAKNTDKKTGYRTCSLLCMPVFNPDGDLIGVTQLINK 1097
Score = 44.4 bits (100), Expect = 0.013
Identities = 17/32 (53%), Positives = 26/32 (81%)
Query: 61 DARTGYKTELILCMPICNYEGDVVGVAQIINK 92
D +TGY+T +LCMP+ N EG+++GV Q+IN+
Sbjct: 676 DQKTGYRTCSLLCMPVHNPEGELLGVTQLINR 707
Score = 41.1 bits (92), Expect = 0.12
Identities = 26/63 (41%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
Query: 291 VARSNKSLNIS-DVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLINKFT 347
VA+ LNI D+ + + G RT LLCMP+ N + D+IGV QLINK
Sbjct: 1040 VAQMGIPLNIPFDLYDYPDSETAKNTDKKTGYRTCSLLCMPVFNPDGDLIGVTQLINKNK 1099
Query: 348 EGD 350
GD
Sbjct: 1100 LGD 1102
Score = 39.1 bits (87), Expect = 0.49
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 291 VARSNKSLNIS-DVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLINKFT 347
VA++ + LNI D+ N + G RT LLCMP+ N +++GV QLIN+
Sbjct: 650 VAQTGEELNIPFDLYNHPDSNTAKTTDQKTGYRTCSLLCMPVHNPEGELLGVTQLINRRK 709
Query: 348 EG 349
G
Sbjct: 710 PG 711
Score = 39.1 bits (87), Expect = 0.49
Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 61 DARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEH-TTESTLD 104
D + GY+T +L +P+ N GD+V V Q INK H T+S D
Sbjct: 877 DKKNGYRTYSMLALPLLNELGDLVAVVQAINKLKPNHQPTDSLFD 921
>UniRef50_Q7M8J3 Cluster: RESPONSE REGULATOR PROTEIN-CheY-like nd an
HD-GYP domain; n=2; Wolinella succinogenes|Rep: RESPONSE
REGULATOR PROTEIN-CheY-like nd an HD-GYP domain -
Wolinella succinogenes
Length = 637
Score = 48.0 bits (109), Expect = 0.001
Identities = 19/38 (50%), Positives = 27/38 (71%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
+FN E+D +TGY T I+ +PI N EG+++G Q INK
Sbjct: 367 RFNPEVDKKTGYLTRSIIALPIFNSEGEIIGAYQAINK 404
>UniRef50_Q4DUD4 Cluster: CAMP-specific phosphodiesterase, putative;
n=2; Trypanosoma|Rep: CAMP-specific phosphodiesterase,
putative - Trypanosoma cruzi
Length = 654
Score = 48.0 bits (109), Expect = 0.001
Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 2/143 (1%)
Query: 454 LCRWILSVKKNY-RPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHD 512
L +++++ +NY + YHN HA + Q +F +L+ ++ E++ +A L
Sbjct: 164 LLSFLMALFENYSKENAYHNALHAADSVQMLFLILREKPATLIFTENEVILAFLATLSLG 223
Query: 513 LDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVM 571
H G +NAF + + PL ++Y +T + + +LN E N + +
Sbjct: 224 FVHPGVSNAFLARIDHPLVLVYGDMTTQQSAGLTALLYLLNREENRFIDLFANSGTQPFS 283
Query: 572 HVVETAILSTDLAMYFKKKSKFL 594
+ ++ T L + +S L
Sbjct: 284 QFLREILVETVLGTAPRLRSSLL 306
>UniRef50_Q090R6 Cluster: CGMP-dependent 3',5'-cyclic
phosphodiesterase; n=2; Cystobacterineae|Rep:
CGMP-dependent 3',5'-cyclic phosphodiesterase -
Stigmatella aurantiaca DW4/3-1
Length = 533
Score = 47.6 bits (108), Expect = 0.001
Identities = 20/45 (44%), Positives = 28/45 (62%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDG 95
Y +FN D +GY T+ ILC+P+ + GDV GV Q +NK +G
Sbjct: 134 YADERFNRSFDTSSGYHTQTILCVPMRDASGDVTGVIQALNKRNG 178
Score = 38.7 bits (86), Expect = 0.65
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINKF 346
IA VA + +NI D R N + +T+LC+P+ +A+ DV GV Q +NK
Sbjct: 117 IAGQVASTGAVINIPDAYADERFNRSFDTSSGYHTQTILCVPMRDASGDVTGVIQALNK- 175
Query: 347 TEGDVSIFEAFAIFCGLGIHNTQMYENA 374
G + E + LG + ENA
Sbjct: 176 RNGRIFDAEDEELLLALGANAAGAIENA 203
>UniRef50_UPI00006CA67B Cluster: GAF domain containing protein; n=1;
Tetrahymena thermophila SB210|Rep: GAF domain containing
protein - Tetrahymena thermophila SB210
Length = 932
Score = 47.2 bits (107), Expect = 0.002
Identities = 21/47 (44%), Positives = 32/47 (68%), Gaps = 1/47 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYE-GDVVGVAQIINKTDGEHTTE 100
+FN EID + Y T+ +LC+P+ + + G++VGV Q INK DG T +
Sbjct: 659 RFNPEIDKKNNYLTKSVLCVPVIDSDKGNLVGVMQAINKNDGFFTKD 705
Score = 39.1 bits (87), Expect = 0.49
Identities = 24/73 (32%), Positives = 42/73 (57%), Gaps = 5/73 (6%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANK-DVIGVAQLINK---- 345
VA + K LNI D + R N +N+ +++LC+P+++++K +++GV Q INK
Sbjct: 642 VANTMKPLNILDAHKDSRFNPEIDKKNNYLTKSVLCVPVIDSDKGNLVGVMQAINKNDGF 701
Query: 346 FTEGDVSIFEAFA 358
FT+ D + A
Sbjct: 702 FTKDDEGCLQIMA 714
>UniRef50_A5V6C5 Cluster: Putative adenylate/guanylate cyclase; n=1;
Sphingomonas wittichii RW1|Rep: Putative
adenylate/guanylate cyclase - Sphingomonas wittichii RW1
Length = 903
Score = 47.2 bits (107), Expect = 0.002
Identities = 20/44 (45%), Positives = 27/44 (61%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
Y +FN E+D TG+ T ILC PI + G +GV Q++NK D
Sbjct: 418 YADPRFNPEVDRATGFVTRSILCQPIFDKHGGRIGVTQVLNKRD 461
>UniRef50_Q4DJT7 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 930
Score = 47.2 bits (107), Expect = 0.002
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 457 WILSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHR 516
++L ++ +R +++ HA AQ +A+L M MS E+L + A LC + H
Sbjct: 569 FLLQIQDGFRDPEFYTADHAAECAQFFYALLFHSGMIPHMSHAELLAAVTAALCMEYGHP 628
Query: 517 GTNNAFQTKTESPLAI-LYSTSTMEHHHFDQCVMILNSE 554
G + + + P A ++S +EH + I + E
Sbjct: 629 GVSGCLLSAAQDPAAAGIHSCLLLEHRRLESLGEIFSQE 667
>UniRef50_Q24GJ8 Cluster: GAF domain containing protein; n=1;
Tetrahymena thermophila SB210|Rep: GAF domain containing
protein - Tetrahymena thermophila SB210
Length = 744
Score = 46.8 bits (106), Expect = 0.002
Identities = 20/50 (40%), Positives = 29/50 (58%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTE 100
Y +FN + D + YK+ ILC+PI + G V+G Q INK +G T +
Sbjct: 447 YADERFNKDFDKKMNYKSRTILCVPIIDEHGRVLGAIQCINKLNGHFTKD 496
Score = 39.5 bits (88), Expect = 0.37
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK- 345
IA VA + ++LNI + R N + + RT+LC+PI++ + V+G Q INK
Sbjct: 430 IAGFVATTKQTLNILNAYADERFNKDFDKKMNYKSRTILCVPIIDEHGRVLGAIQCINKL 489
Query: 346 ---FTEGDVSIFEAFAIFCGLGIHNTQMYE 372
FT+ D ++ A F + + N Y+
Sbjct: 490 NGHFTKDDEALLMVIADFSRIVLKNAINYD 519
>UniRef50_A0NF29 Cluster: ENSANGP00000029810; n=2;
Endopterygota|Rep: ENSANGP00000029810 - Anopheles
gambiae str. PEST
Length = 144
Score = 46.8 bits (106), Expect = 0.002
Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLDHNYEPRPGQIT 115
F +D TG+KT ILC PIC+ EG V+GVAQ+ NK + + D PR I+
Sbjct: 83 FYKGVDESTGFKTRNILCFPICDEEG-VIGVAQLCNKRQLQRRDVVSEDTGEVPRVDTIS 141
>UniRef50_Q23PX5 Cluster: GAF domain containing protein; n=1;
Tetrahymena thermophila SB210|Rep: GAF domain containing
protein - Tetrahymena thermophila SB210
Length = 906
Score = 46.4 bits (105), Expect = 0.003
Identities = 43/172 (25%), Positives = 86/172 (50%), Gaps = 19/172 (11%)
Query: 55 QFNSEIDARTGYKTELILCMPICNY-EGDVVGVAQIINKTDGEHTTESTLDHNYEPRPGQ 113
+FNS+ D + Y+T+ +LC+PI + + ++GV Q INK DG+ T+ D + Q
Sbjct: 637 RFNSDADKKNNYRTKSVLCLPIKDQNQSHIIGVLQAINKKDGDFFTKE--DESLLIIISQ 694
Query: 114 ITRGPVASHWYSLYYFGNQRLYTYLRRKLSHSG---SKEFSSRDVEVFRRYLTFCGIGIQ 170
+ + + SLY+ + Y + L ++G SKE S + + V + +Q
Sbjct: 695 LATAVLRN---SLYH-DEREAYRNNLKSLVNTGIDLSKEKSIKTLIVRSTAILIDKFDVQ 750
Query: 171 NAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKIMTEARDLLKCERC 222
A+++ + + ++NQ++ R ++ L L + + E +++K E+C
Sbjct: 751 QARIW---IYDLQQNQLI----RYFVDDDQVLSILQGQAINE--EVIKEEKC 793
Score = 41.9 bits (94), Expect = 0.070
Identities = 23/61 (37%), Positives = 39/61 (63%), Gaps = 2/61 (3%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKD-VIGVAQLINKFTEG 349
VA++ + LN+ D Q R N+ + +N+ +++LC+PI + N+ +IGV Q INK +G
Sbjct: 620 VAQTGEILNVLDAHQDYRFNSDADKKNNYRTKSVLCLPIKDQNQSHIIGVLQAINK-KDG 678
Query: 350 D 350
D
Sbjct: 679 D 679
>UniRef50_A0LL31 Cluster: Serine phosphatase; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Serine phosphatase -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 438
Score = 46.0 bits (104), Expect = 0.004
Identities = 19/45 (42%), Positives = 31/45 (68%), Gaps = 1/45 (2%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDG 95
Y +F+ E D +TGY+T +LC+P+ + V+GV+Q+IN+ DG
Sbjct: 116 YRDARFHQEFDRKTGYRTHSMLCVPL-KIKDRVIGVSQVINRLDG 159
>UniRef50_A0LKA7 Cluster: Metal dependent phosphohydrolase; n=4;
Deltaproteobacteria|Rep: Metal dependent
phosphohydrolase - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 576
Score = 46.0 bits (104), Expect = 0.004
Identities = 17/38 (44%), Positives = 30/38 (78%)
Query: 59 EIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
E DARTGY+++ ++ +P+ N+E +++GV Q++N TD E
Sbjct: 173 EYDARTGYRSKSMVVIPMKNHENEIIGVLQLLNATDPE 210
>UniRef50_Q1IM31 Cluster: Serine phosphatase; n=1; Acidobacteria
bacterium Ellin345|Rep: Serine phosphatase -
Acidobacteria bacterium (strain Ellin345)
Length = 612
Score = 45.6 bits (103), Expect = 0.006
Identities = 19/46 (41%), Positives = 31/46 (67%), Gaps = 1/46 (2%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK-TDGEHTTE 100
F+ D +TGY T+ +LC+PI ++ ++VGV Q++N+ T G T E
Sbjct: 270 FDRSFDQKTGYTTKSLLCLPIRHHNNEIVGVLQLLNQSTHGRFTPE 315
Score = 37.9 bits (84), Expect = 1.1
Identities = 18/63 (28%), Positives = 35/63 (55%)
Query: 287 IALAVARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINKF 346
+A VA + + +N++D + + ++LLC+PI + N +++GV QL+N+
Sbjct: 248 VAGRVAETGEVINVADAYTLPFFDRSFDQKTGYTTKSLLCLPIRHHNNEIVGVLQLLNQS 307
Query: 347 TEG 349
T G
Sbjct: 308 THG 310
>UniRef50_Q6MLW2 Cluster: NtrC family transcriptional regulator;
n=1; Bdellovibrio bacteriovorus|Rep: NtrC family
transcriptional regulator - Bdellovibrio bacteriovorus
Length = 530
Score = 45.2 bits (102), Expect = 0.008
Identities = 16/37 (43%), Positives = 29/37 (78%)
Query: 60 IDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
+D++TGY+TE +L +P+ +G V+GV +++NK DG+
Sbjct: 127 VDSKTGYQTEKVLAVPLHWKDGKVIGVIEVLNKADGD 163
>UniRef50_A4J938 Cluster: Metal dependent phosphohydrolase; n=1;
Desulfotomaculum reducens MI-1|Rep: Metal dependent
phosphohydrolase - Desulfotomaculum reducens MI-1
Length = 366
Score = 44.8 bits (101), Expect = 0.010
Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 12/103 (11%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAG-ENSAG--VRTLLCMPIVNANKDVIGVAQLINK-- 345
V + +S +SDV L+D+ S + S G R+LLC+P++ IG QL+NK
Sbjct: 90 VTANGQSQMVSDV---LKDSRWSQRFDQSTGFITRSLLCVPLITQTS-CIGCLQLVNKLD 145
Query: 346 ---FTEGDVSIFEAFAIFCGLGIHNTQMYENACKLMAKQKVAL 385
F E D+S+ EA A G+ + N+++Y + + VAL
Sbjct: 146 GQLFDEDDLSLCEALAGVIGMAVENSRLYTDLKTMFKSFLVAL 188
>UniRef50_A0XZ13 Cluster: Metal dependent phosphohydrolase; n=1;
Alteromonadales bacterium TW-7|Rep: Metal dependent
phosphohydrolase - Alteromonadales bacterium TW-7
Length = 553
Score = 44.8 bits (101), Expect = 0.010
Identities = 17/39 (43%), Positives = 30/39 (76%)
Query: 59 EIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEH 97
E+DARTGY+T+ +L +P+ +++ D++GV Q+IN D +
Sbjct: 139 EMDARTGYRTQSMLTIPLKDHQDDILGVIQLINVKDSNN 177
>UniRef50_Q23RX8 Cluster: GAF domain containing protein; n=1;
Tetrahymena thermophila SB210|Rep: GAF domain containing
protein - Tetrahymena thermophila SB210
Length = 686
Score = 44.8 bits (101), Expect = 0.010
Identities = 18/40 (45%), Positives = 28/40 (70%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
+FN ++D TGY+T+ ILC+PI + + VVG + INK +
Sbjct: 432 RFNKQVDFDTGYRTKTILCVPIKDQKNQVVGCLEAINKVN 471
Score = 37.1 bits (82), Expect = 2.0
Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 297 SLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----FTEGDVS 352
++N+ D + R N + +T+LC+PI + V+G + INK F + D
Sbjct: 421 AMNVFDAYEDPRFNKQVDFDTGYRTKTILCVPIKDQKNQVVGCLEAINKVNDFFNKQDQE 480
Query: 353 IFEAFAIFCGLGIHNTQMYE 372
+ E FC + N+ ++
Sbjct: 481 MLEIMGSFCSSILQNSLKFD 500
>UniRef50_Q22VA7 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Tetrahymena thermophila SB210
Length = 624
Score = 44.8 bits (101), Expect = 0.010
Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Query: 506 VACLCHDLDHRGTNNAFQTKTESPLAILY-STSTMEHHHFDQCVMILNSESN-NIFQALS 563
+A L HDL+H+G N ++ K + +I Y +E+ H + IL S + N F AL
Sbjct: 351 IAALGHDLNHKGLGNLYKVKRNAQCSINYCELGVLENMHASKLFQILQSNNELNYFTALK 410
Query: 564 PRD-YKDVMHVVETAILSTDLAMYFKKKSK 592
++ + ++ + I STD+ + K +K
Sbjct: 411 DQNKIQQFKRIIVSCITSTDMQKHSKLTAK 440
Score = 35.1 bits (77), Expect = 8.1
Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
Query: 416 YSFQFHDFDLTDEDTCRATLRMFLQCELVEKFHIPY--DVLCRWILSVKKNYRPVKYHNW 473
++FQ H + T+++ C T +M ++ + + K Y + + I ++ NY + YHNW
Sbjct: 182 HNFQMHLY--TNKELCDITFKM-MEYQGIYKDQSSYTAEQMKLLIKNLCLNYNVIPYHNW 238
Query: 474 RHALNVAQTM 483
HA +V Q +
Sbjct: 239 THAFSVFQNL 248
>UniRef50_Q5BYM4 Cluster: SJCHGC06481 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06481 protein - Schistosoma
japonicum (Blood fluke)
Length = 178
Score = 44.4 bits (100), Expect = 0.013
Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 609 KKELLCGMMMTACDVSAIAKPWEVQHRIAKLVADEFFDQGDLEKLQLNQQPIA-MMDREK 667
+K+L+ +++ D+S A+P V + EFF Q D EKL P+A MDR K
Sbjct: 37 QKDLVMVIILKISDISNEARPLNVAGPWINRLLAEFFHQSDYEKLV--GLPVAPFMDRHK 94
Query: 668 KDELPQMQVGFIDTICLPLYKVLSDTFPWMTPL 700
+ Q GFI + LPL++ L+ P + P+
Sbjct: 95 VTK-SASQCGFIRFVILPLFESLAKLLPEVKPI 126
>UniRef50_Q82SM4 Cluster: Bacterial type II secretion system protein
E:GAF domain; n=5; Betaproteobacteria|Rep: Bacterial
type II secretion system protein E:GAF domain -
Nitrosomonas europaea
Length = 795
Score = 44.0 bits (99), Expect = 0.017
Identities = 20/52 (38%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Query: 54 IQFNSEIDARTGYKTELILCMPICNY-EGDVVGVAQIINKTDGEHTTESTLD 104
++F E+D RTGY+T+ +L +PI N + D++GV Q+IN E ++ +D
Sbjct: 124 LRFLQEVDKRTGYRTKQMLVVPILNAGDNDLLGVVQLINNKADEPFSQRVVD 175
>UniRef50_A2G4P7 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1554
Score = 44.0 bits (99), Expect = 0.017
Identities = 58/302 (19%), Positives = 114/302 (37%), Gaps = 18/302 (5%)
Query: 405 DEIPSAETYNLYSFQFHDFDLTD--EDTCRATLRMFLQCELVEKFHIPYDVLCRWILSVK 462
D PS L S + D+ TD +D + + F L+ + I + +L +
Sbjct: 1011 DNSPSVPQSLLISVKEIDYAATDTIDDAFKIVVSGFYHLGLISSYTISVSKILMLVLEIS 1070
Query: 463 KNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMSDLE--ILGLLVACLCHDLDHRGTNN 520
Y P + ++ H L+ T +++ K E MS + L +L+A LC +LD
Sbjct: 1071 TRY-PEGFRSFAHTLD---TFKYLVRALKFEELMSTPKNKCLSMLLASLCCELDRPNFEE 1126
Query: 521 AFQTKTESPLAILYSTSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILS 580
+ E AI + I+ E NI + + + +++ +
Sbjct: 1127 LGEVALE---AIAECNGICVDSGCNSLTEIIRVEECNILENIKEDEQRNIWKDTFRFAHA 1183
Query: 581 TDLAMYFKKKSKFLELVDNGE-FDWQAQEKKELLCGMMMTACDVSAIAKPWEVQHRIAKL 639
TDL+ +F+ + ++ + FD + + +M D+ + P
Sbjct: 1184 TDLSRHFEIMDTLQQCLEEEDGFDSSKETHLNAMLDAVMKCADLHDVILPLNELEEKRYE 1243
Query: 640 VADEFFDQGDLEKLQLNQQPIAMMDREKKDELPQMQ--VGFIDTICLPLYKVLSDTFPWM 697
+ +FF G++ L + + + + Q + +GF ICLPL+ + +
Sbjct: 1244 FSRDFFMFGEI----LRCKGMFFDGEASRTTINQKESNLGFFMYICLPLFAAVGKSIAGF 1299
Query: 698 TP 699
P
Sbjct: 1300 EP 1301
>UniRef50_Q31L46 Cluster: Metal dependent phosphohydrolase; n=2;
Synechococcus elongatus|Rep: Metal dependent
phosphohydrolase - Synechococcus sp. (strain PCC 7942)
(Anacystis nidulans R2)
Length = 560
Score = 43.2 bits (97), Expect = 0.030
Identities = 16/38 (42%), Positives = 26/38 (68%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
QFN+ D R Y+T +L +P+C+ G V+GV Q++N+
Sbjct: 129 QFNASFDQRLNYRTCSMLVLPMCDQTGSVIGVIQLVNR 166
>UniRef50_Q8F1G6 Cluster: Sigma factor sigB regulation protein rsbU;
n=4; Leptospira|Rep: Sigma factor sigB regulation
protein rsbU - Leptospira interrogans
Length = 556
Score = 42.7 bits (96), Expect = 0.040
Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Query: 51 YITIQFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTTESTLDH 105
Y +FN D +TGY+T ++C+P+ E V+G +I+NKT S L++
Sbjct: 69 YSDSRFNPSWDQKTGYRTRSLICVPLF-VENKVIGTLEILNKTQNRSFDSSDLNY 122
>UniRef50_A4LZ56 Cluster: Diguanylate cyclase with GAF sensor; n=3;
Geobacter|Rep: Diguanylate cyclase with GAF sensor -
Geobacter bemidjiensis Bem
Length = 704
Score = 42.7 bits (96), Expect = 0.040
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 15/117 (12%)
Query: 269 HTVFELGAPRRPHDALPA-----IALAVARSNKSLNISDVEQWLRDNNMS-AGENSAGVR 322
H VF LG LP IA VA+S + L ++DVE +D+ ++ A +
Sbjct: 386 HIVFTLGMTLNIARCLPVKVGKGIAGMVAQSGQPLLVNDVE---KDSRVAMANRLRFKSK 442
Query: 323 TLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIHNTQMYENA 374
+L+CMP+ +K +IGV L +K FT+ D+ + +FA L I T++ E +
Sbjct: 443 SLICMPLKLKDK-IIGVLNLSDKKNLAPFTDADLQVLTSFANLASLMIERTEVLEES 498
>UniRef50_Q95Z92 Cluster: Possible phosphodiesterase; n=2;
Leishmania|Rep: Possible phosphodiesterase - Leishmania
major
Length = 725
Score = 42.7 bits (96), Expect = 0.040
Identities = 33/156 (21%), Positives = 62/156 (39%), Gaps = 3/156 (1%)
Query: 470 YHNWRHALNVAQTMFAMLKTGKMERFMSDLEILGLLVACLCHDLDHRGTNNAFQTKTESP 529
YHN HA + Q M + + SD EI +A L D+ H G ++ + P
Sbjct: 200 YHNATHAADALQMMSLFFREPTVNFLFSDEEIAICFLAVLAVDVAHPGASDTLLVALDHP 259
Query: 530 LAILY-STSTMEHHHFDQCVMILNSESNNIFQALSPRDYKDVMHVVETAILSTDLAMYFK 588
LA ++ + EH +L E N F D H+++ A+ L +
Sbjct: 260 LASVFGDVAITEHASLLVLTSLLVLEDNFFFSTPDMAVSVDSAHLLKEALYDVVLNAALR 319
Query: 589 KKSKFLELVDNGEFDWQA--QEKKELLCGMMMTACD 622
+ + + + E + + +L+ +++ AC+
Sbjct: 320 SRPSLMSALRDIETSGRITDADAPKLMAALLVMACN 355
>UniRef50_A6GDL8 Cluster: Sigma-54 dependent transcriptional
regulator, Fis family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: Sigma-54 dependent transcriptional
regulator, Fis family protein - Plesiocystis pacifica
SIR-1
Length = 590
Score = 42.3 bits (95), Expect = 0.053
Identities = 17/44 (38%), Positives = 30/44 (68%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHT 98
+F++ ID +TG+ T +L +PI + G+V+GV Q++N G+ T
Sbjct: 156 RFDASIDRQTGFSTRSMLALPIRDSAGEVIGVLQLLNAGRGQFT 199
>UniRef50_Q8YVS0 Cluster: Adenylate cyclase; n=6; Cyanobacteria|Rep:
Adenylate cyclase - Anabaena sp. (strain PCC 7120)
Length = 860
Score = 41.9 bits (94), Expect = 0.070
Identities = 15/34 (44%), Positives = 26/34 (76%)
Query: 59 EIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
+ID + GY+T +LCMP+ N + +++GV Q++NK
Sbjct: 354 QIDQQNGYRTCSLLCMPVFNGDQELIGVTQLVNK 387
Score = 39.5 bits (88), Expect = 0.37
Identities = 16/84 (19%), Positives = 47/84 (55%)
Query: 150 FSSRDVEVFRRYLTFCGIGIQNAQLFESSVLEYKRNQILLALARSIFEEQSNLECLVTKI 209
F+S D ++F+ + + +++++ F + + + ++ +S+ + +LE + ++
Sbjct: 220 FTSADEQLFQEFAPSIRLILESSRSFYIATQKQRAAAAMMKAVKSLSQSSLDLEDTLKRV 279
Query: 210 MTEARDLLKCERCAVFILDTDHCE 233
M EA++L+ +R ++++D D E
Sbjct: 280 MDEAKELMNADRSTLWLIDRDRHE 303
Score = 39.5 bits (88), Expect = 0.37
Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 291 VARSNKSLNIS-DVEQWLRDNNMSAGENSAGVRT--LLCMPIVNANKDVIGVAQLINKFT 347
VA S + LNI D+ + G RT LLCMP+ N ++++IGV QL+NK
Sbjct: 330 VAASGQKLNIPFDLYDHPDSATAKQIDQQNGYRTCSLLCMPVFNGDQELIGVTQLVNKKK 389
Query: 348 EGD 350
G+
Sbjct: 390 TGE 392
>UniRef50_Q30S23 Cluster: Metal dependent phosphohydrolase; n=2;
Bacteria|Rep: Metal dependent phosphohydrolase -
Thiomicrospira denitrificans (strain ATCC 33889 / DSM
1351)
Length = 796
Score = 41.5 bits (93), Expect = 0.093
Identities = 15/41 (36%), Positives = 29/41 (70%)
Query: 59 EIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGEHTT 99
+ D TGY+++ +L +P+ N+E +++GV Q++NK D + T
Sbjct: 390 KFDEGTGYRSKSMLVIPLKNHESEIIGVLQLLNKYDDNNET 430
>UniRef50_A7AVW3 Cluster: cAMP-specific phosphodiesterase, putative;
n=1; Babesia bovis|Rep: cAMP-specific phosphodiesterase,
putative - Babesia bovis
Length = 525
Score = 41.5 bits (93), Expect = 0.093
Identities = 17/44 (38%), Positives = 27/44 (61%)
Query: 188 LLALARSIFEEQSNLECLVTKIMTEARDLLKCERCAVFILDTDH 231
LL L S+F ++ ++ V + T AR L++ ERC V+I+D H
Sbjct: 327 LLTLMHSLFADRLGIQSCVVALTTHARKLIQAERCTVYIVDRSH 370
>UniRef50_Q2JV17 Cluster: GAF domain protein; n=2;
Synechococcus|Rep: GAF domain protein - Synechococcus
sp. (strain JA-3-3Ab) (Cyanobacteria
bacteriumYellowstone A-Prime)
Length = 406
Score = 41.1 bits (92), Expect = 0.12
Identities = 14/37 (37%), Positives = 28/37 (75%)
Query: 56 FNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINK 92
FNS++D +TGY+T +L +P+ + G+++G Q++N+
Sbjct: 122 FNSQVDQQTGYRTRSLLTVPMRDPSGNILGALQLLNR 158
>UniRef50_Q1N6Q6 Cluster: HD-GYP domain protein; n=1; Oceanobacter
sp. RED65|Rep: HD-GYP domain protein - Oceanobacter sp.
RED65
Length = 743
Score = 41.1 bits (92), Expect = 0.12
Identities = 15/34 (44%), Positives = 24/34 (70%)
Query: 61 DARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
D +TGY+T+ +L P+ N+ +V+GV Q+IN D
Sbjct: 315 DEQTGYRTQSVLTFPLLNHRAEVIGVLQLINARD 348
>UniRef50_Q22SL3 Cluster: GAF domain containing protein; n=1;
Tetrahymena thermophila SB210|Rep: GAF domain containing
protein - Tetrahymena thermophila SB210
Length = 624
Score = 41.1 bits (92), Expect = 0.12
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEG-DVVGVAQIINKTDGEHTTE 100
+FN EID YKT +L PI + +G +V+GV Q +NK G T +
Sbjct: 407 RFNKEIDKMMNYKTNTVLAFPIFDRDGINVLGVIQSVNKLKGYFTKD 453
>UniRef50_A6C6H7 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 574
Score = 40.7 bits (91), Expect = 0.16
Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
Query: 312 MSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK-----FTEGDVSIFEAFAIFCGLGIH 366
MS S +R+++C+P+V+ D++GV Q+ + F + D+ + A A L +
Sbjct: 259 MSESITSLRIRSMMCVPLVSQGGDILGVIQIATRDIGQQFDKDDLDVLVAIAQQASLAVE 318
Query: 367 NTQMYENACK 376
N +++E+ K
Sbjct: 319 NAKLHEDLVK 328
>UniRef50_A6C1F0 Cluster: Probable two-component response regulator;
n=1; Planctomyces maris DSM 8797|Rep: Probable
two-component response regulator - Planctomyces maris
DSM 8797
Length = 673
Score = 40.7 bits (91), Expect = 0.16
Identities = 13/42 (30%), Positives = 29/42 (69%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
+F+ +D +G++T +LC+P+ N G+++G +++NK G+
Sbjct: 266 RFDPSVDKSSGFRTHNLLCVPLRNNAGELIGAFEVMNKEKGK 307
>UniRef50_A4C9A9 Cluster: Metal dependent phosphohydrolase; n=1;
Pseudoalteromonas tunicata D2|Rep: Metal dependent
phosphohydrolase - Pseudoalteromonas tunicata D2
Length = 527
Score = 40.7 bits (91), Expect = 0.16
Identities = 15/32 (46%), Positives = 26/32 (81%)
Query: 60 IDARTGYKTELILCMPICNYEGDVVGVAQIIN 91
+D +TGY+T+ +L +P+ N+EG++ GV Q+IN
Sbjct: 127 MDQKTGYRTKSVLTVPMQNHEGEINGVLQLIN 158
>UniRef50_Q5WXL9 Cluster: Putative uncharacterized protein; n=1;
Legionella pneumophila str. Lens|Rep: Putative
uncharacterized protein - Legionella pneumophila (strain
Lens)
Length = 258
Score = 40.3 bits (90), Expect = 0.21
Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 8/83 (9%)
Query: 390 YHATASAEDTSKLCQDEIPSAETYNLYSFQFHDFDLTDEDTCRATLR------MFLQCEL 443
+++ S D +C I S NLYS Q H F + E +L FL+ E+
Sbjct: 28 HYSCESFYDRESMCSPRITSIAVTNLYSRQTHSFSIHQEAEINGSLEDIDNNYDFLEKEM 87
Query: 444 VEKFH--IPYDVLCRWILSVKKN 464
+ KF+ + + ++CRW+ KN
Sbjct: 88 LNKFYKFVDHHLICRWVHWNMKN 110
>UniRef50_Q31JE4 Cluster: Metal dependent phosphohydrolase; n=1;
Thiomicrospira crunogena XCL-2|Rep: Metal dependent
phosphohydrolase - Thiomicrospira crunogena (strain
XCL-2)
Length = 524
Score = 40.3 bits (90), Expect = 0.21
Identities = 16/36 (44%), Positives = 26/36 (72%)
Query: 61 DARTGYKTELILCMPICNYEGDVVGVAQIINKTDGE 96
D + Y+T+ +L +P+ N++ DV+GV Q+IN TD E
Sbjct: 128 DQQVHYRTQSMLTIPLKNFDHDVIGVLQLINATDQE 163
>UniRef50_A0C3Y8 Cluster: Chromosome undetermined scaffold_148,
whole genome shotgun sequence; n=6; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_148,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 594
Score = 40.3 bits (90), Expect = 0.21
Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 5/74 (6%)
Query: 291 VARSNKSLNISDVEQWLRDNNMSAGENSAGVRTLLCMPIVNANKDVIGVAQLINK----F 346
VA+++ LNI D + R N +N+ +TLL PI++ +K +GV Q +NK F
Sbjct: 336 VAQNHTILNIEDAYRDQRFNTQQDAKNNYKTKTLLVSPILDGDK-CVGVLQCVNKSNGFF 394
Query: 347 TEGDVSIFEAFAIF 360
T+ D ++ + A F
Sbjct: 395 TKDDEALLQIMAEF 408
Score = 38.7 bits (86), Expect = 0.65
Identities = 20/47 (42%), Positives = 31/47 (65%), Gaps = 3/47 (6%)
Query: 55 QFNSEIDARTGYKTELILCMPICNYEGD-VVGVAQIINKTDGEHTTE 100
+FN++ DA+ YKT+ +L PI +GD VGV Q +NK++G T +
Sbjct: 353 RFNTQQDAKNNYKTKTLLVSPI--LDGDKCVGVLQCVNKSNGFFTKD 397
>UniRef50_UPI0000EBF1DD Cluster: PREDICTED: similar to cGMP-specific
phosphodiesterase; n=1; Bos taurus|Rep: PREDICTED:
similar to cGMP-specific phosphodiesterase - Bos taurus
Length = 89
Score = 39.9 bits (89), Expect = 0.28
Identities = 18/30 (60%), Positives = 23/30 (76%)
Query: 633 QHRIAKLVADEFFDQGDLEKLQLNQQPIAM 662
Q IA+LVA EFFDQGD E+ +LN +P A+
Sbjct: 17 QRLIAELVATEFFDQGDRERKELNIEPAAL 46
>UniRef50_A0L8S2 Cluster: Metal dependent phosphohydrolase; n=6;
Proteobacteria|Rep: Metal dependent phosphohydrolase -
Magnetococcus sp. (strain MC-1)
Length = 746
Score = 39.9 bits (89), Expect = 0.28
Identities = 15/34 (44%), Positives = 24/34 (70%)
Query: 61 DARTGYKTELILCMPICNYEGDVVGVAQIINKTD 94
D TGY+T +L +P+ N+E +++GV Q+IN D
Sbjct: 326 DKNTGYRTTSVLAVPMKNHENELIGVLQLINAKD 359
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.321 0.134 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 858,825,390
Number of Sequences: 1657284
Number of extensions: 34281819
Number of successful extensions: 75097
Number of sequences better than 10.0: 296
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 73914
Number of HSP's gapped (non-prelim): 754
length of query: 852
length of database: 575,637,011
effective HSP length: 107
effective length of query: 745
effective length of database: 398,307,623
effective search space: 296739179135
effective search space used: 296739179135
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 77 (35.1 bits)
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