Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000056-TA|BGIBMGA000056-PA|IPR001128|Cytochrome P450,
IPR002401|E-class P450, group I
(395 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 149 2e-35
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 149 2e-35
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 149 2e-35
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 149 2e-35
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 120 7e-27
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 120 7e-27
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 120 7e-27
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 120 9e-27
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 120 9e-27
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 120 9e-27
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 120 9e-27
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 120 9e-27
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 120 9e-27
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 120 9e-27
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 120 9e-27
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 120 9e-27
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 120 9e-27
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 120 1e-26
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 120 1e-26
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 118 3e-26
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 118 3e-26
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 118 3e-26
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 118 3e-26
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 118 3e-26
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 118 3e-26
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 118 3e-26
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 118 3e-26
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 118 3e-26
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 118 4e-26
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 118 5e-26
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 118 5e-26
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 118 5e-26
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 118 5e-26
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 118 5e-26
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 118 5e-26
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 118 5e-26
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 118 5e-26
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 117 8e-26
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 115 3e-25
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 115 3e-25
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 114 4e-25
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 114 4e-25
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 114 4e-25
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 114 4e-25
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 114 6e-25
BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein. 114 6e-25
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 114 6e-25
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 114 6e-25
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 114 6e-25
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 114 6e-25
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 114 6e-25
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 114 6e-25
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 114 6e-25
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 114 6e-25
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 113 1e-24
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 113 1e-24
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 113 1e-24
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 113 1e-24
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 113 1e-24
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 113 1e-24
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 113 1e-24
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 112 2e-24
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 112 2e-24
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 112 2e-24
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 112 2e-24
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 111 3e-24
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 111 3e-24
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 111 3e-24
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 111 4e-24
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 111 5e-24
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 110 7e-24
AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, famil... 110 7e-24
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 110 7e-24
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 110 1e-23
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 110 1e-23
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 110 1e-23
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 110 1e-23
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 109 1e-23
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 109 1e-23
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 109 1e-23
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 109 1e-23
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 108 3e-23
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 108 3e-23
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 107 5e-23
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 107 5e-23
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 107 5e-23
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 107 5e-23
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 107 5e-23
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 107 5e-23
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 107 5e-23
AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 107 5e-23
AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 107 5e-23
AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 107 5e-23
AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 107 5e-23
AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 107 5e-23
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 107 5e-23
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 107 7e-23
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 106 1e-22
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 105 2e-22
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 103 8e-22
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 103 8e-22
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 103 8e-22
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 103 8e-22
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 100 8e-21
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 100 8e-21
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 100 8e-21
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 100 8e-21
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 100 8e-21
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 100 8e-21
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 100 8e-21
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 100 8e-21
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 100 8e-21
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 100 8e-21
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 99 1e-20
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 99 1e-20
AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 99 1e-20
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 99 1e-20
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 98 4e-20
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 98 5e-20
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 98 5e-20
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 98 5e-20
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 98 5e-20
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 98 5e-20
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 98 5e-20
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 98 5e-20
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 98 5e-20
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 97 1e-19
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 97 1e-19
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 97 1e-19
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 97 1e-19
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 97 1e-19
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 97 1e-19
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 97 1e-19
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 97 1e-19
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 97 1e-19
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 97 1e-19
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 97 1e-19
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 96 2e-19
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 96 2e-19
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 96 2e-19
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 95 4e-19
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 95 4e-19
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 95 4e-19
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 95 4e-19
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 95 4e-19
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 95 4e-19
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 95 4e-19
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 94 7e-19
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 94 7e-19
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 93 2e-18
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 91 5e-18
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 91 6e-18
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 91 8e-18
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 91 8e-18
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 91 8e-18
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 91 8e-18
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 90 1e-17
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 89 3e-17
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 89 3e-17
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 89 3e-17
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 89 3e-17
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 88 4e-17
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 88 4e-17
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 88 4e-17
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 88 4e-17
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 88 4e-17
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 88 4e-17
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 88 4e-17
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 88 4e-17
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 88 6e-17
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 88 6e-17
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 88 6e-17
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 87 8e-17
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 87 8e-17
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 87 8e-17
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 87 8e-17
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 87 8e-17
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 87 8e-17
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 87 8e-17
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 87 8e-17
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 87 8e-17
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 87 8e-17
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 87 8e-17
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 87 8e-17
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 87 8e-17
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 87 8e-17
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 87 8e-17
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 87 1e-16
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 87 1e-16
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 87 1e-16
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 87 1e-16
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 87 1e-16
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 87 1e-16
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 86 2e-16
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 86 2e-16
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 86 2e-16
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 86 2e-16
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 86 2e-16
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 86 2e-16
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 86 2e-16
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 86 2e-16
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 86 2e-16
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 86 2e-16
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 86 2e-16
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 86 2e-16
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 85 3e-16
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 85 3e-16
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 85 3e-16
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 85 3e-16
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 85 3e-16
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 85 3e-16
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 85 4e-16
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 85 4e-16
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 85 4e-16
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 85 5e-16
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 84 7e-16
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 84 7e-16
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 84 7e-16
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 84 7e-16
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 84 7e-16
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 84 7e-16
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 84 7e-16
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 84 7e-16
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 84 7e-16
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 84 9e-16
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 84 9e-16
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 84 9e-16
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 84 9e-16
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 84 9e-16
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 84 9e-16
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 84 9e-16
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 83 1e-15
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 83 1e-15
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 83 1e-15
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 83 2e-15
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 83 2e-15
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 82 3e-15
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 81 5e-15
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 81 5e-15
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 81 5e-15
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 81 5e-15
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 81 5e-15
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 81 5e-15
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 81 5e-15
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 81 5e-15
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 81 5e-15
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 81 5e-15
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 81 5e-15
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 81 5e-15
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 81 7e-15
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 80 2e-14
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 79 2e-14
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 79 2e-14
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 78 5e-14
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 78 6e-14
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 78 6e-14
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 78 6e-14
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 78 6e-14
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 78 6e-14
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 78 6e-14
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 78 6e-14
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 77 1e-13
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 77 1e-13
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 76 2e-13
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 76 2e-13
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 76 2e-13
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 76 2e-13
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 76 2e-13
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 76 2e-13
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 76 2e-13
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 76 2e-13
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 75 3e-13
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 75 4e-13
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 75 6e-13
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 75 6e-13
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 75 6e-13
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 74 8e-13
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 74 8e-13
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 74 8e-13
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 74 8e-13
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 74 8e-13
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 74 8e-13
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 74 8e-13
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 74 8e-13
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 74 8e-13
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 74 1e-12
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 74 1e-12
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 73 1e-12
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 73 1e-12
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 73 2e-12
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 73 2e-12
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 72 4e-12
AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family... 72 4e-12
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 72 4e-12
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 72 4e-12
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 71 7e-12
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 71 7e-12
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 71 9e-12
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 70 2e-11
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 70 2e-11
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 70 2e-11
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 69 4e-11
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 69 4e-11
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 69 4e-11
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 69 4e-11
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 69 4e-11
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 69 4e-11
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 69 4e-11
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 69 4e-11
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 69 4e-11
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 69 4e-11
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 69 4e-11
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 69 4e-11
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 69 4e-11
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 69 4e-11
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 69 4e-11
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 68 7e-11
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 68 7e-11
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 67 9e-11
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 67 9e-11
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 67 9e-11
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 67 1e-10
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 67 1e-10
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 67 1e-10
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 67 1e-10
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 67 1e-10
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 67 1e-10
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 67 1e-10
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 67 1e-10
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 67 1e-10
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 67 1e-10
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 67 1e-10
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 67 1e-10
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 66 2e-10
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 66 3e-10
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 66 3e-10
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 66 3e-10
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 66 3e-10
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 66 3e-10
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 66 3e-10
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 65 4e-10
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 65 4e-10
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 65 4e-10
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 65 4e-10
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 4e-10
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 65 4e-10
BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 65 4e-10
BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 65 4e-10
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 65 4e-10
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 65 4e-10
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 65 4e-10
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 65 4e-10
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 65 4e-10
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 65 4e-10
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 4e-10
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 4e-10
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 4e-10
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 4e-10
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 4e-10
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 65 4e-10
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 65 4e-10
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 65 4e-10
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 65 4e-10
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 65 4e-10
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 65 4e-10
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 65 4e-10
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 65 4e-10
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 65 4e-10
AC011737-1|AAX88915.1| 382|Homo sapiens unknown protein. 65 4e-10
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 65 5e-10
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 65 5e-10
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 64 8e-10
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 63 1e-09
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 63 1e-09
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 63 1e-09
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 62 3e-09
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 61 8e-09
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 61 8e-09
AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 61 8e-09
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 60 1e-08
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 60 1e-08
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 60 1e-08
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 56 2e-07
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 55 5e-07
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 55 5e-07
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 54 7e-07
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 54 9e-07
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 54 9e-07
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 54 1e-06
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 52 4e-06
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 49 3e-05
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 49 3e-05
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 49 3e-05
AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 49 3e-05
AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 49 3e-05
AF029403-1|AAC95426.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 49 3e-05
BC029155-1|AAH29155.1| 489|Homo sapiens Unknown (protein for IM... 48 6e-05
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 47 1e-04
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 47 1e-04
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 47 1e-04
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 46 3e-04
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 45 5e-04
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 42 0.003
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 42 0.003
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 42 0.004
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 41 0.007
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 41 0.007
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 41 0.007
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 41 0.007
BC056258-1|AAH56258.1| 359|Homo sapiens CYP19A1 protein protein. 40 0.015
BC020767-1|AAH20767.1| 360|Homo sapiens Unknown (protein for IM... 40 0.015
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 39 0.035
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 39 0.035
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 39 0.035
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 39 0.035
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 39 0.035
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 39 0.035
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 35 0.44
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 35 0.44
AC005336-2|AAC27731.1| 93|Homo sapiens F20191_1, partial CDS p... 35 0.44
AY904366-1|AAW83816.1| 62|Homo sapiens cytochrome p4502C9 prot... 34 1.0
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 34 1.0
M37197-1|AAA51924.1| 998|Homo sapiens CCAAT-box-binding factor ... 32 3.1
BC034475-1|AAH34475.1| 1054|Homo sapiens CCAAT/enhancer binding ... 32 3.1
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 32 3.1
AC007390-3|AAY14815.1| 1054|Homo sapiens unknown protein. 32 3.1
AB209749-1|BAD92986.1| 210|Homo sapiens cytochrome P450, family... 32 3.1
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 32 3.1
S77873-1|AAD14267.1| 68|Homo sapiens CYP2E1 protein. 31 9.4
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 31 9.4
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 31 9.4
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 149 bits (360), Expect = 2e-35
Identities = 84/224 (37%), Positives = 130/224 (58%), Gaps = 9/224 (4%)
Query: 179 SLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
+ LD +L D L+ E+IRE++D F+ DT+A A+ + L ++GS PEVQ+K+
Sbjct: 298 AFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDH 357
Query: 238 EILAEVG-DNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGS 296
E+ G ++ T + L KL YLE VIKETLR++ VP AR D ++ Y + KG+
Sbjct: 358 ELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGT 417
Query: 297 SIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSM 351
I+ LH+ P++ P+ +F+PER+F EN + PFS G RNCIG+ +A+M
Sbjct: 418 EAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEE 477
Query: 352 KVLLVHVFRHYKVTGDISNTEHRL--GVLLKPATGHHIKLDKRN 393
K +L + RH+ + + E L ++L+P+ G IKL +RN
Sbjct: 478 KTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRN 521
Score = 63.7 bits (148), Expect = 1e-09
Identities = 36/132 (27%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
Query: 25 IPELPGKLPIIGHGLMFFGDGKHIHKTFKWLGEEAIKLGGVVSVNFGPIKVYIVADPDDS 84
IP + P++GH L+ DG+ + EE + ++ + GP+ + + + ++
Sbjct: 50 IPTVARAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMP-LLKLWVGPVPMVALYNAENV 108
Query: 85 AVVATNC--LAKGFFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNN 142
V+ T+ + K Y F ++G G+L + W+ +RK L P F IL +F+DI N
Sbjct: 109 EVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNE 168
Query: 143 QGRRLIMQLAAH 154
Q L+ +L H
Sbjct: 169 QANILVKKLEKH 180
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 149 bits (360), Expect = 2e-35
Identities = 84/224 (37%), Positives = 130/224 (58%), Gaps = 9/224 (4%)
Query: 179 SLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
+ LD +L D L+ E+IRE++D F+ DT+A A+ + L ++GS PEVQ+K+
Sbjct: 298 AFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDH 357
Query: 238 EILAEVG-DNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGS 296
E+ G ++ T + L KL YLE VIKETLR++ VP AR D ++ Y + KG+
Sbjct: 358 ELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGT 417
Query: 297 SIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSM 351
I+ LH+ P++ P+ +F+PER+F EN + PFS G RNCIG+ +A+M
Sbjct: 418 EAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEE 477
Query: 352 KVLLVHVFRHYKVTGDISNTEHRL--GVLLKPATGHHIKLDKRN 393
K +L + RH+ + + E L ++L+P+ G IKL +RN
Sbjct: 478 KTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRN 521
Score = 63.7 bits (148), Expect = 1e-09
Identities = 36/132 (27%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
Query: 25 IPELPGKLPIIGHGLMFFGDGKHIHKTFKWLGEEAIKLGGVVSVNFGPIKVYIVADPDDS 84
IP + P++GH L+ DG+ + EE + ++ + GP+ + + + ++
Sbjct: 50 IPTVARAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMP-LLKLWVGPVPMVALYNAENV 108
Query: 85 AVVATNC--LAKGFFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNN 142
V+ T+ + K Y F ++G G+L + W+ +RK L P F IL +F+DI N
Sbjct: 109 EVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNE 168
Query: 143 QGRRLIMQLAAH 154
Q L+ +L H
Sbjct: 169 QANILVKKLEKH 180
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 149 bits (360), Expect = 2e-35
Identities = 84/224 (37%), Positives = 130/224 (58%), Gaps = 9/224 (4%)
Query: 179 SLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
+ LD +L D L+ E+IRE++D F+ DT+A A+ + L ++GS PEVQ+K+
Sbjct: 276 AFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDH 335
Query: 238 EILAEVG-DNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGS 296
E+ G ++ T + L KL YLE VIKETLR++ VP AR D ++ Y + KG+
Sbjct: 336 ELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGT 395
Query: 297 SIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSM 351
I+ LH+ P++ P+ +F+PER+F EN + PFS G RNCIG+ +A+M
Sbjct: 396 EAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEE 455
Query: 352 KVLLVHVFRHYKVTGDISNTEHRL--GVLLKPATGHHIKLDKRN 393
K +L + RH+ + + E L ++L+P+ G IKL +RN
Sbjct: 456 KTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRN 499
Score = 52.4 bits (120), Expect = 3e-06
Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNC--LAKGFFYDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP+ + + + ++ V+ T+ + K Y F ++G G+L + W+ +RK L P F
Sbjct: 73 GPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTF 132
Query: 129 KQQILNNFMDIFNNQGRRLIMQLAAH 154
IL +F+DI N Q L+ +L H
Sbjct: 133 HFTILEDFLDIMNEQANILVKKLEKH 158
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 149 bits (360), Expect = 2e-35
Identities = 84/224 (37%), Positives = 130/224 (58%), Gaps = 9/224 (4%)
Query: 179 SLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
+ LD +L D L+ E+IRE++D F+ DT+A A+ + L ++GS PEVQ+K+
Sbjct: 298 AFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDH 357
Query: 238 EILAEVG-DNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGS 296
E+ G ++ T + L KL YLE VIKETLR++ VP AR D ++ Y + KG+
Sbjct: 358 ELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGT 417
Query: 297 SIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSM 351
I+ LH+ P++ P+ +F+PER+F EN + PFS G RNCIG+ +A+M
Sbjct: 418 EAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEE 477
Query: 352 KVLLVHVFRHYKVTGDISNTEHRL--GVLLKPATGHHIKLDKRN 393
K +L + RH+ + + E L ++L+P+ G IKL +RN
Sbjct: 478 KTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRN 521
Score = 63.7 bits (148), Expect = 1e-09
Identities = 36/132 (27%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
Query: 25 IPELPGKLPIIGHGLMFFGDGKHIHKTFKWLGEEAIKLGGVVSVNFGPIKVYIVADPDDS 84
IP + P++GH L+ DG+ + EE + ++ + GP+ + + + ++
Sbjct: 50 IPTVARAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMP-LLKLWVGPVPMVALYNAENV 108
Query: 85 AVVATNC--LAKGFFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNN 142
V+ T+ + K Y F ++G G+L + W+ +RK L P F IL +F+DI N
Sbjct: 109 EVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNE 168
Query: 143 QGRRLIMQLAAH 154
Q L+ +L H
Sbjct: 169 QANILVKKLEKH 180
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 120 bits (290), Expect = 7e-27
Identities = 72/241 (29%), Positives = 129/241 (53%), Gaps = 14/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ L + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L + L
Sbjct: 259 SRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTL 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ EI A + + T D + ++ YL+ V+ ETLR++ V + R
Sbjct: 319 YELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN----VFAPFSMGK 338
D+++ IPKGS + I LH P++ + +FRPER+ + + ++ PF G
Sbjct: 379 KDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGP 438
Query: 339 RNCIGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGV----LLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V +++ T+ L + LL+P +K+D R+
Sbjct: 439 RNCIGMRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLDTQGLLQPEKPIVLKVDSRDG 497
Query: 395 T 395
T
Sbjct: 498 T 498
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 120 bits (290), Expect = 7e-27
Identities = 72/241 (29%), Positives = 129/241 (53%), Gaps = 14/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ L + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L + L
Sbjct: 259 SRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTL 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ EI A + + T D + ++ YL+ V+ ETLR++ V + R
Sbjct: 319 YELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN----VFAPFSMGK 338
D+++ IPKGS + I LH P++ + +FRPER+ + + ++ PF G
Sbjct: 379 KDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGP 438
Query: 339 RNCIGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGV----LLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V +++ T+ L + LL+P +K+D R+
Sbjct: 439 RNCIGMRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLDTQGLLQPEKPIVLKVDSRDG 497
Query: 395 T 395
T
Sbjct: 498 T 498
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 120 bits (290), Expect = 7e-27
Identities = 72/241 (29%), Positives = 129/241 (53%), Gaps = 14/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ L + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L + L
Sbjct: 259 SRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTL 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ EI A + + T D + ++ YL+ V+ ETLR++ V + R
Sbjct: 319 YELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN----VFAPFSMGK 338
D+++ IPKGS + I LH P++ + +FRPER+ + + ++ PF G
Sbjct: 379 KDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGP 438
Query: 339 RNCIGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGV----LLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V +++ T+ L + LL+P +K+D R+
Sbjct: 439 RNCIGMRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLDTQGLLQPEKPIVLKVDSRDG 497
Query: 395 T 395
T
Sbjct: 498 T 498
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 109 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 168
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 169 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 228
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 229 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 288
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 289 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 348
Query: 395 T 395
T
Sbjct: 349 T 349
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 186 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 245
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 246 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 305
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 306 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 365
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 366 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 425
Query: 395 T 395
T
Sbjct: 426 T 426
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 120 bits (289), Expect = 9e-27
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 120 bits (288), Expect = 1e-26
Identities = 70/241 (29%), Positives = 134/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 120 bits (288), Expect = 1e-26
Identities = 72/241 (29%), Positives = 129/241 (53%), Gaps = 14/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ L + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L + L
Sbjct: 259 SRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTL 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ EI A + + T D + ++ YL+ V+ ETLR++ V + R
Sbjct: 319 YELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCM 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN----VFAPFSMGK 338
D+++ IPKGS + I LH P++ + +FRPER+ + + ++ PF G
Sbjct: 379 KDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGP 438
Query: 339 RNCIGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGV----LLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V +++ T+ L + LL+P +K+D R+
Sbjct: 439 RNCIGMRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLDTQGLLQPEKPIVLKVDSRDG 497
Query: 395 T 395
T
Sbjct: 498 T 498
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 118 bits (285), Expect = 3e-26
Identities = 70/241 (29%), Positives = 133/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + + PF G
Sbjct: 379 KDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 118 bits (285), Expect = 3e-26
Identities = 70/241 (29%), Positives = 133/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 258 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIM 317
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 318 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 377
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + + PF G
Sbjct: 378 KDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSG 437
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 438 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 497
Query: 395 T 395
T
Sbjct: 498 T 498
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 118 bits (285), Expect = 3e-26
Identities = 70/232 (30%), Positives = 126/232 (54%), Gaps = 9/232 (3%)
Query: 171 ESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYP 229
+ + +T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +P
Sbjct: 289 DKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHP 348
Query: 230 EVQQKIYDEI--LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
E Q++ E+ L + D K++ D L +L +L +KE+LR++ P I+R D+ L
Sbjct: 349 EYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL 408
Query: 288 KN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNC 341
+ IPKG + I + +H +P PD + P R+ EN F PFS G RNC
Sbjct: 409 PDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNC 468
Query: 342 IGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLDKRN 393
IG+ +AM MKV+L + H++ D + +L ++++ G ++++ N
Sbjct: 469 IGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLN 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 67 SVNFGPIKVYIVADPDDSAVVATNCLAK-----GFFYDFSNAYIGNGILCAKLPLWKQQR 121
+V GPI +IV D+ TN A F F ++G GIL + W + R
Sbjct: 89 TVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHR 148
Query: 122 KALNPAFKQQILNNFMDIFNNQGRRLI---MQLAAHGPGSFDHHHPILINNLESSLQETI 178
+ L PAF IL +++ IFN ++ LA+ G D I + L+ SLQ+ I
Sbjct: 149 RMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLD-SLQKCI 207
Query: 179 SLLDFILDQDKSKQFLTDEEIREQID 204
D + S+ T E+ ++
Sbjct: 208 FSFDSHCQERPSEYIATILELSALVE 233
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 118 bits (285), Expect = 3e-26
Identities = 58/181 (32%), Positives = 109/181 (60%), Gaps = 5/181 (2%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
P++ + +F PER+ +N L + PF G RNCIG +A+ ++K+ ++ ++
Sbjct: 403 HDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQN 462
Query: 362 Y 362
+
Sbjct: 463 F 463
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 118 bits (285), Expect = 3e-26
Identities = 70/232 (30%), Positives = 126/232 (54%), Gaps = 9/232 (3%)
Query: 171 ESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYP 229
+ + +T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +P
Sbjct: 289 DKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHP 348
Query: 230 EVQQKIYDEI--LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
E Q++ E+ L + D K++ D L +L +L +KE+LR++ P I+R D+ L
Sbjct: 349 EYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL 408
Query: 288 KN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNC 341
+ IPKG + I + +H +P PD + P R+ EN F PFS G RNC
Sbjct: 409 PDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNC 468
Query: 342 IGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLDKRN 393
IG+ +AM MKV+L + H++ D + +L ++++ G ++++ N
Sbjct: 469 IGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLN 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 67 SVNFGPIKVYIVADPDDSAVVATNCLAK-----GFFYDFSNAYIGNGILCAKLPLWKQQR 121
+V GPI +IV D+ TN A F F ++G GIL + W + R
Sbjct: 89 TVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHR 148
Query: 122 KALNPAFKQQILNNFMDIFNNQGRRLI---MQLAAHGPGSFDHHHPILINNLESSLQETI 178
+ L PAF IL +++ IFN ++ LA+ G D I + L+ SLQ+ I
Sbjct: 149 RMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLD-SLQKCI 207
Query: 179 SLLDFILDQDKSKQFLTDEEIREQID 204
D + S+ T E+ ++
Sbjct: 208 FSFDSHCQERPSEYIATILELSALVE 233
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 118 bits (285), Expect = 3e-26
Identities = 70/232 (30%), Positives = 126/232 (54%), Gaps = 9/232 (3%)
Query: 171 ESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYP 229
+ + +T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +P
Sbjct: 289 DKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHP 348
Query: 230 EVQQKIYDEI--LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
E Q++ E+ L + D K++ D L +L +L +KE+LR++ P I+R D+ L
Sbjct: 349 EYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL 408
Query: 288 KN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNC 341
+ IPKG + I + +H +P PD + P R+ EN F PFS G RNC
Sbjct: 409 PDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNC 468
Query: 342 IGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLDKRN 393
IG+ +AM MKV+L + H++ D + +L ++++ G ++++ N
Sbjct: 469 IGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLN 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 67 SVNFGPIKVYIVADPDDSAVVATNCLAK-----GFFYDFSNAYIGNGILCAKLPLWKQQR 121
+V GPI +IV D+ TN A F F ++G GIL + W + R
Sbjct: 89 TVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHR 148
Query: 122 KALNPAFKQQILNNFMDIFNNQGRRLI---MQLAAHGPGSFDHHHPILINNLESSLQETI 178
+ L PAF IL +++ IFN ++ LA+ G D I + L+ SLQ+ I
Sbjct: 149 RMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLD-SLQKCI 207
Query: 179 SLLDFILDQDKSKQFLTDEEIREQID 204
D + S+ T E+ ++
Sbjct: 208 FSFDSHCQERPSEYIATILELSALVE 233
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 118 bits (285), Expect = 3e-26
Identities = 70/232 (30%), Positives = 126/232 (54%), Gaps = 9/232 (3%)
Query: 171 ESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYP 229
+ + +T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +P
Sbjct: 223 DKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHP 282
Query: 230 EVQQKIYDEI--LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
E Q++ E+ L + D K++ D L +L +L +KE+LR++ P I+R D+ L
Sbjct: 283 EYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL 342
Query: 288 KN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNC 341
+ IPKG + I + +H +P PD + P R+ EN F PFS G RNC
Sbjct: 343 PDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNC 402
Query: 342 IGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLDKRN 393
IG+ +AM MKV+L + H++ D + +L ++++ G ++++ N
Sbjct: 403 IGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLN 454
Score = 49.2 bits (112), Expect = 3e-05
Identities = 40/142 (28%), Positives = 61/142 (42%), Gaps = 9/142 (6%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAK-----GFFYDFSNAYIGNGILCAKLPLWKQQRKALN 125
GPI +IV D+ TN A F F ++G GIL + W + R+ L
Sbjct: 27 GPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLT 86
Query: 126 PAFKQQILNNFMDIFNNQGRRLI---MQLAAHGPGSFDHHHPILINNLESSLQETISLLD 182
PAF IL +++ IFN ++ LA+ G D I + L+ SLQ+ I D
Sbjct: 87 PAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLD-SLQKCIFSFD 145
Query: 183 FILDQDKSKQFLTDEEIREQID 204
+ S+ T E+ ++
Sbjct: 146 SHCQERPSEYIATILELSALVE 167
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 118 bits (285), Expect = 3e-26
Identities = 70/232 (30%), Positives = 126/232 (54%), Gaps = 9/232 (3%)
Query: 171 ESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYP 229
+ + +T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +P
Sbjct: 289 DKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHP 348
Query: 230 EVQQKIYDEI--LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
E Q++ E+ L + D K++ D L +L +L +KE+LR++ P I+R D+ L
Sbjct: 349 EYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL 408
Query: 288 KN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNC 341
+ IPKG + I + +H +P PD + P R+ EN F PFS G RNC
Sbjct: 409 PDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNC 468
Query: 342 IGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLDKRN 393
IG+ +AM MKV+L + H++ D + +L ++++ G ++++ N
Sbjct: 469 IGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLN 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 67 SVNFGPIKVYIVADPDDSAVVATNCLAK-----GFFYDFSNAYIGNGILCAKLPLWKQQR 121
+V GPI +IV D+ TN A F F ++G GIL + W + R
Sbjct: 89 TVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHR 148
Query: 122 KALNPAFKQQILNNFMDIFNNQGRRLI---MQLAAHGPGSFDHHHPILINNLESSLQETI 178
+ L PAF IL +++ IFN ++ LA+ G D I + L+ SLQ+ I
Sbjct: 149 RMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLD-SLQKCI 207
Query: 179 SLLDFILDQDKSKQFLTDEEIREQID 204
D + S+ T E+ ++
Sbjct: 208 FSFDSHCQERPSEYIATILELSALVE 233
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 118 bits (285), Expect = 3e-26
Identities = 70/232 (30%), Positives = 126/232 (54%), Gaps = 9/232 (3%)
Query: 171 ESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYP 229
+ + +T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +P
Sbjct: 289 DKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHP 348
Query: 230 EVQQKIYDEI--LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
E Q++ E+ L + D K++ D L +L +L +KE+LR++ P I+R D+ L
Sbjct: 349 EYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL 408
Query: 288 KN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNC 341
+ IPKG + I + +H +P PD + P R+ EN F PFS G RNC
Sbjct: 409 PDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNC 468
Query: 342 IGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLDKRN 393
IG+ +AM MKV+L + H++ D + +L ++++ G ++++ N
Sbjct: 469 IGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLN 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 67 SVNFGPIKVYIVADPDDSAVVATNCLAK-----GFFYDFSNAYIGNGILCAKLPLWKQQR 121
+V GPI +IV D+ TN A F F ++G GIL + W + R
Sbjct: 89 TVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHR 148
Query: 122 KALNPAFKQQILNNFMDIFNNQGRRLI---MQLAAHGPGSFDHHHPILINNLESSLQETI 178
+ L PAF IL +++ IFN ++ LA+ G D I + L+ SLQ+ I
Sbjct: 149 RMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLD-SLQKCI 207
Query: 179 SLLDFILDQDKSKQFLTDEEIREQID 204
D + S+ T E+ ++
Sbjct: 208 FSFDSHCQERPSEYIATILELSALVE 233
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 118 bits (284), Expect = 4e-26
Identities = 70/241 (29%), Positives = 133/241 (55%), Gaps = 13/241 (5%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLL 222
+ LE + + + L ++D SK+ L+D E+ Q IF+ A +T+++ L +++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGCETTSSVLSFIM 318
Query: 223 TVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTD 282
+ ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378
Query: 283 IDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMG 337
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF G
Sbjct: 379 KDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRNK 394
RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 498
Query: 395 T 395
T
Sbjct: 499 T 499
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 118 bits (283), Expect = 5e-26
Identities = 70/242 (28%), Positives = 134/242 (55%), Gaps = 14/242 (5%)
Query: 168 NNLESSLQETISLLDFILDQDK------SKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
+ LE + + + L ++D K S + L+D E+ Q IF+ A ++T+++ L ++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFI 318
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKT 281
+ + ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 MYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVC 378
Query: 282 DIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSM 336
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF
Sbjct: 379 KKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGS 438
Query: 337 GKRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRN 393
G RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 GPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 498
Query: 394 KT 395
T
Sbjct: 499 GT 500
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 118 bits (283), Expect = 5e-26
Identities = 70/242 (28%), Positives = 134/242 (55%), Gaps = 14/242 (5%)
Query: 168 NNLESSLQETISLLDFILDQDK------SKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
+ LE + + + L ++D K S + L+D E+ Q IF+ A ++T+++ L ++
Sbjct: 259 SRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFI 318
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKT 281
+ + ++P+VQQK+ +EI A + + T D + ++ YL+ V+ ETLR++ + + R
Sbjct: 319 MYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVC 378
Query: 282 DIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSM 336
D+++ IPKG + I LH+ P++ + +F PER+ +N + ++ PF
Sbjct: 379 KKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGS 438
Query: 337 GKRNCIGKVYAMMSMKVLLVHVFRH--YKVTGDIS-NTEHRLGVLLKPATGHHIKLDKRN 393
G RNCIG +A+M+MK+ L+ V ++ +K + + LG LL+P +K++ R+
Sbjct: 439 GPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 498
Query: 394 KT 395
T
Sbjct: 499 GT 500
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 118 bits (283), Expect = 5e-26
Identities = 58/181 (32%), Positives = 109/181 (60%), Gaps = 5/181 (2%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 173 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 232
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 233 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 292
Query: 307 QHPQWGPDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
P++ + +F PER+ +N L + PF G RNCIG +A+ ++K+ ++ ++
Sbjct: 293 HDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQN 352
Query: 362 Y 362
+
Sbjct: 353 F 353
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 118 bits (283), Expect = 5e-26
Identities = 58/181 (32%), Positives = 109/181 (60%), Gaps = 5/181 (2%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
P++ + +F PER+ +N L + PF G RNCIG +A+ ++K+ ++ ++
Sbjct: 403 HDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQN 462
Query: 362 Y 362
+
Sbjct: 463 F 463
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 118 bits (283), Expect = 5e-26
Identities = 58/181 (32%), Positives = 109/181 (60%), Gaps = 5/181 (2%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
P++ + +F PER+ +N L + PF G RNCIG +A+ ++K+ ++ ++
Sbjct: 403 HDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQN 462
Query: 362 Y 362
+
Sbjct: 463 F 463
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 118 bits (283), Expect = 5e-26
Identities = 58/181 (32%), Positives = 109/181 (60%), Gaps = 5/181 (2%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
P++ + +F PER+ +N L + PF G RNCIG +A+ ++K+ ++ ++
Sbjct: 403 HDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQN 462
Query: 362 Y 362
+
Sbjct: 463 F 463
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 118 bits (283), Expect = 5e-26
Identities = 58/181 (32%), Positives = 109/181 (60%), Gaps = 5/181 (2%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
P++ + +F PER+ +N L + PF G RNCIG +A+ ++K+ ++ ++
Sbjct: 403 HDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQN 462
Query: 362 Y 362
+
Sbjct: 463 F 463
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 118 bits (283), Expect = 5e-26
Identities = 58/181 (32%), Positives = 109/181 (60%), Gaps = 5/181 (2%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
P++ + +F PER+ +N L + PF G RNCIG +A+ ++K+ ++ ++
Sbjct: 403 HDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQN 462
Query: 362 Y 362
+
Sbjct: 463 F 463
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 117 bits (281), Expect = 8e-26
Identities = 68/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +DK+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY-T 291
E+ + D K++ D L +L +L +KE+LR++ +P AR D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG+ I + +H +P PD + P R+ EN F PFS G RNCIG+ +
Sbjct: 414 IPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L +++ D ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVE 517
Score = 40.3 bits (90), Expect = 0.012
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRL---IMQLAA 153
FY ++G+G+L + W+ R+ L PAF IL ++ IF+ + +LA
Sbjct: 124 FYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAM 183
Query: 154 HGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFLT 195
G D I + L+ SLQ+ I D Q+K +++T
Sbjct: 184 EGSTCLDVFEHISLMTLD-SLQKCIFSFDSNC-QEKPSEYIT 223
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 115 bits (276), Expect = 3e-25
Identities = 57/182 (31%), Positives = 109/182 (59%), Gaps = 6/182 (3%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPERWFTE------NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFR 360
P++ + +F PE F++ +L + PF G RNCIG +A+ ++K+ ++ +
Sbjct: 403 HDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQ 462
Query: 361 HY 362
++
Sbjct: 463 NF 464
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 115 bits (276), Expect = 3e-25
Identities = 57/182 (31%), Positives = 109/182 (59%), Gaps = 6/182 (3%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPERWFTE------NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFR 360
P++ + +F PE F++ +L + PF G RNCIG +A+ ++K+ ++ +
Sbjct: 403 HDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQ 462
Query: 361 HY 362
++
Sbjct: 463 NF 464
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 114 bits (275), Expect = 4e-25
Identities = 61/203 (30%), Positives = 114/203 (56%), Gaps = 10/203 (4%)
Query: 170 LESSLQETISLLDFILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTV 224
L+ + + + L ++D SK + L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 261 LKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYE 320
Query: 225 VGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDID 284
+ ++P+VQQK+ EI + + T D + +L YL+ V+ ETLR++ V + R D
Sbjct: 321 LATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKD 380
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKR 339
+++ IPKG + I LH P++ + +F PER+ +N + ++ PF G R
Sbjct: 381 VEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 440
Query: 340 NCIGKVYAMMSMKVLLVHVFRHY 362
NCIG +A+++MK+ LV V +++
Sbjct: 441 NCIGMRFALVNMKLALVRVLQNF 463
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 114 bits (275), Expect = 4e-25
Identities = 61/203 (30%), Positives = 114/203 (56%), Gaps = 10/203 (4%)
Query: 170 LESSLQETISLLDFILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTV 224
L+ + + + L ++D SK + L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 261 LKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYE 320
Query: 225 VGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDID 284
+ ++P+VQQK+ EI + + T D + +L YL+ V+ ETLR++ V + R D
Sbjct: 321 LATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKD 380
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKR 339
+++ IPKG + I LH P++ + +F PER+ +N + ++ PF G R
Sbjct: 381 VEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 440
Query: 340 NCIGKVYAMMSMKVLLVHVFRHY 362
NCIG +A+++MK+ LV V +++
Sbjct: 441 NCIGMRFALVNMKLALVRVLQNF 463
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 114 bits (275), Expect = 4e-25
Identities = 61/203 (30%), Positives = 114/203 (56%), Gaps = 10/203 (4%)
Query: 170 LESSLQETISLLDFILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTV 224
L+ + + + L ++D SK + L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 261 LKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYE 320
Query: 225 VGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDID 284
+ ++P+VQQK+ EI + + T D + +L YL+ V+ ETLR++ V + R D
Sbjct: 321 LATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKD 380
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKR 339
+++ IPKG + I LH P++ + +F PER+ +N + ++ PF G R
Sbjct: 381 VEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 440
Query: 340 NCIGKVYAMMSMKVLLVHVFRHY 362
NCIG +A+++MK+ LV V +++
Sbjct: 441 NCIGMRFALVNMKLALVRVLQNF 463
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 114 bits (275), Expect = 4e-25
Identities = 61/203 (30%), Positives = 114/203 (56%), Gaps = 10/203 (4%)
Query: 170 LESSLQETISLLDFILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTV 224
L+ + + + L ++D SK + L+D E+ Q IF+ A ++T+++ L +++
Sbjct: 261 LKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYE 320
Query: 225 VGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDID 284
+ ++P+VQQK+ EI + + T D + +L YL+ V+ ETLR++ V + R D
Sbjct: 321 LATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKD 380
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKR 339
+++ IPKG + I LH P++ + +F PER+ +N + ++ PF G R
Sbjct: 381 VEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 440
Query: 340 NCIGKVYAMMSMKVLLVHVFRHY 362
NCIG +A+++MK+ LV V +++
Sbjct: 441 NCIGMRFALVNMKLALVRVLQNF 463
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 114 bits (274), Expect = 6e-25
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L L +L +KE+LR++ VP I+R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 48.4 bits (110), Expect = 4e-05
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 96 FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LA 152
FFY F ++G+G+L + W + R+ L PAF IL +M IFN+ + + LA
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLA 182
Query: 153 AHGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
+ G D I + L+ SLQ+ + D Q+K +++
Sbjct: 183 SEGSACLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein.
Length = 372
Score = 114 bits (274), Expect = 6e-25
Identities = 67/210 (31%), Positives = 116/210 (55%), Gaps = 10/210 (4%)
Query: 192 QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTK 251
Q LT +EI + L+A DT++ L + + ++ +PEVQQ +Y EI+ +G+ T
Sbjct: 163 QALTLQEIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVPTA 222
Query: 252 DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIM-LGTLHQHPQ 310
+PK+ + A++KETLR++ V+P R T DL + Y IPKG+ + + T +Q
Sbjct: 223 ADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDEN 282
Query: 311 WGPDAHQFRPERWF----TENLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
+ P A +FRPERW + ++ F PF G R+CIG+ A + + ++++ + +H+++
Sbjct: 283 F-PRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEI 341
Query: 365 -TGDISNTEH-RLGVLLKPATGHHIKLDKR 392
T +N H + LL P H++ R
Sbjct: 342 KTSSQTNAVHAKTHGLLTPGGPIHVRFVNR 371
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 114 bits (274), Expect = 6e-25
Identities = 67/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Query: 181 LDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
LD +L +D+S +D ++ ++ FL+A DT A ++ ++L + PE Q++ +E+
Sbjct: 287 LDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEV 346
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSSI 298
+GD +T D L ++ Y IKET R+ VP+I+R L + T+P G ++
Sbjct: 347 RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITV 406
Query: 299 GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKV 353
+ + LH +P + F P R+ EN + + PFS G RNCIG+ +AM+ +KV
Sbjct: 407 VLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKV 466
Query: 354 LLVHVFRHYKVTGDISN-TEHRLGVLLKPATGHHIKLDK 391
+ + H++VT D + +LKP G ++ L K
Sbjct: 467 TIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKK 505
Score = 36.7 bits (81), Expect = 0.14
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKG-FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP + + + DPD + + + K + FS +G G+ P W Q R+ L P F
Sbjct: 85 GPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLI 148
IL ++++ + + ++
Sbjct: 145 HFNILKAYIEVMAHSVKMML 164
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 114 bits (274), Expect = 6e-25
Identities = 67/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Query: 181 LDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
LD +L +D+S +D ++ ++ FL+A DT A ++ ++L + PE Q++ +E+
Sbjct: 287 LDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEV 346
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSSI 298
+GD +T D L ++ Y IKET R+ VP+I+R L + T+P G ++
Sbjct: 347 RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITV 406
Query: 299 GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKV 353
+ + LH +P + F P R+ EN + + PFS G RNCIG+ +AM+ +KV
Sbjct: 407 VLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKV 466
Query: 354 LLVHVFRHYKVTGDISN-TEHRLGVLLKPATGHHIKLDK 391
+ + H++VT D + +LKP G ++ L K
Sbjct: 467 TIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKK 505
Score = 36.7 bits (81), Expect = 0.14
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKG-FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP + + + DPD + + + K + FS +G G+ P W Q R+ L P F
Sbjct: 85 GPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLI 148
IL ++++ + + ++
Sbjct: 145 HFNILKAYIEVMAHSVKMML 164
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 114 bits (274), Expect = 6e-25
Identities = 67/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Query: 181 LDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
LD +L +D+S +D ++ ++ FL+A DT A ++ ++L + PE Q++ +E+
Sbjct: 287 LDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEV 346
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSSI 298
+GD +T D L ++ Y IKET R+ VP+I+R L + T+P G ++
Sbjct: 347 RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITV 406
Query: 299 GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKV 353
+ + LH +P + F P R+ EN + + PFS G RNCIG+ +AM+ +KV
Sbjct: 407 VLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKV 466
Query: 354 LLVHVFRHYKVTGDISN-TEHRLGVLLKPATGHHIKLDK 391
+ + H++VT D + +LKP G ++ L K
Sbjct: 467 TIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKK 505
Score = 36.7 bits (81), Expect = 0.14
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKG-FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP + + + DPD + + + K + FS +G G+ P W Q R+ L P F
Sbjct: 85 GPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLI 148
IL ++++ + + ++
Sbjct: 145 HFNILKAYIEVMAHSVKMML 164
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 114 bits (274), Expect = 6e-25
Identities = 67/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Query: 181 LDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
LD +L +D+S +D ++ ++ FL+A DT A ++ ++L + PE Q++ +E+
Sbjct: 287 LDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEV 346
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSSI 298
+GD +T D L ++ Y IKET R+ VP+I+R L + T+P G ++
Sbjct: 347 RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITV 406
Query: 299 GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKV 353
+ + LH +P + F P R+ EN + + PFS G RNCIG+ +AM+ +KV
Sbjct: 407 VLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKV 466
Query: 354 LLVHVFRHYKVTGDISN-TEHRLGVLLKPATGHHIKLDK 391
+ + H++VT D + +LKP G ++ L K
Sbjct: 467 TIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKK 505
Score = 36.7 bits (81), Expect = 0.14
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKG-FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP + + + DPD + + + K + FS +G G+ P W Q R+ L P F
Sbjct: 85 GPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLI 148
IL ++++ + + ++
Sbjct: 145 HFNILKAYIEVMAHSVKMML 164
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 114 bits (274), Expect = 6e-25
Identities = 67/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Query: 181 LDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
LD +L +D+S +D ++ ++ FL+A DT A ++ ++L + PE Q++ +E+
Sbjct: 286 LDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEV 345
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSSI 298
+GD +T D L ++ Y IKET R+ VP+I+R L + T+P G ++
Sbjct: 346 RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITV 405
Query: 299 GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKV 353
+ + LH +P + F P R+ EN + + PFS G RNCIG+ +AM+ +KV
Sbjct: 406 VLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKV 465
Query: 354 LLVHVFRHYKVTGDISN-TEHRLGVLLKPATGHHIKLDK 391
+ + H++VT D + +LKP G ++ L K
Sbjct: 466 TIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKK 504
Score = 36.7 bits (81), Expect = 0.14
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKG-FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP + + + DPD + + + K + FS +G G+ P W Q R+ L P F
Sbjct: 84 GPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGF 143
Query: 129 KQQILNNFMDIFNNQGRRLI 148
IL ++++ + + ++
Sbjct: 144 HFNILKAYIEVMAHSVKMML 163
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 114 bits (274), Expect = 6e-25
Identities = 67/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Query: 181 LDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
LD +L +D+S +D ++ ++ FL+A DT A ++ ++L + PE Q++ +E+
Sbjct: 287 LDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEV 346
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSSI 298
+GD +T D L ++ Y IKET R+ VP+I+R L + T+P G ++
Sbjct: 347 RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITV 406
Query: 299 GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKV 353
+ + LH +P + F P R+ EN + + PFS G RNCIG+ +AM+ +KV
Sbjct: 407 VLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKV 466
Query: 354 LLVHVFRHYKVTGDISN-TEHRLGVLLKPATGHHIKLDK 391
+ + H++VT D + +LKP G ++ L K
Sbjct: 467 TIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKK 505
Score = 36.7 bits (81), Expect = 0.14
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKG-FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP + + + DPD + + + K + FS +G G+ P W Q R+ L P F
Sbjct: 85 GPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLI 148
IL ++++ + + ++
Sbjct: 145 HFNILKAYIEVMAHSVKMML 164
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 114 bits (274), Expect = 6e-25
Identities = 67/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Query: 181 LDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
LD +L +D+S +D ++ ++ FL+A DT A ++ ++L + PE Q++ +E+
Sbjct: 222 LDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEV 281
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSSI 298
+GD +T D L ++ Y IKET R+ VP+I+R L + T+P G ++
Sbjct: 282 RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITV 341
Query: 299 GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKV 353
+ + LH +P + F P R+ EN + + PFS G RNCIG+ +AM+ +KV
Sbjct: 342 VLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKV 401
Query: 354 LLVHVFRHYKVTGDISN-TEHRLGVLLKPATGHHIKLDK 391
+ + H++VT D + +LKP G ++ L K
Sbjct: 402 TIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKK 440
Score = 36.7 bits (81), Expect = 0.14
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKG-FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP + + + DPD + + + K + FS +G G+ P W Q R+ L P F
Sbjct: 20 GPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGF 79
Query: 129 KQQILNNFMDIFNNQGRRLI 148
IL ++++ + + ++
Sbjct: 80 HFNILKAYIEVMAHSVKMML 99
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 114 bits (274), Expect = 6e-25
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L L +L +KE+LR++ VP I+R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 96 FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LA 152
FFY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
Query: 153 AHGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
+ G D I + L+ SLQ+ + D Q+K +++
Sbjct: 183 SEGSACLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 113 bits (272), Expect = 1e-24
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L L +L +KE+LR++ VP I+R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 96 FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LA 152
FFY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
Query: 153 AHGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
+ G D I + L+ SLQ+ + D Q+K +++
Sbjct: 183 SEGSACLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 113 bits (272), Expect = 1e-24
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L L +L +KE+LR++ VP I+R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 96 FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LA 152
FFY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
Query: 153 AHGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
+ G D I + L+ SLQ+ + D Q+K +++
Sbjct: 183 SEGSACLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 113 bits (272), Expect = 1e-24
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L L +L +KE+LR++ VP I+R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 96 FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LA 152
FFY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
Query: 153 AHGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
+ G D I + L+ SLQ+ + D Q+K +++
Sbjct: 183 SEGSACLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 113 bits (272), Expect = 1e-24
Identities = 67/210 (31%), Positives = 116/210 (55%), Gaps = 10/210 (4%)
Query: 192 QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTK 251
Q LT +EI + L+A DT++ L + + ++ +PEVQQ +Y EI+ +G+ T
Sbjct: 163 QALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTA 222
Query: 252 DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIM-LGTLHQHPQ 310
+PK+ + A++KETLR++ V+P R T DL + Y IPKG+ + + T +Q
Sbjct: 223 ADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDEN 282
Query: 311 WGPDAHQFRPERWF----TENLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
+ P A +FRPERW + ++ F PF G R+CIG+ A + + ++++ + +H+++
Sbjct: 283 F-PRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEI 341
Query: 365 -TGDISNTEH-RLGVLLKPATGHHIKLDKR 392
T +N H + LL P H++ R
Sbjct: 342 KTSSQTNAVHAKTHGLLTPGGPIHVRFVNR 371
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 113 bits (272), Expect = 1e-24
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L L +L +KE+LR++ VP I+R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 96 FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LA 152
FFY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
Query: 153 AHGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
+ G D I + L+ SLQ+ + D Q+K +++
Sbjct: 183 SEGSACLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 113 bits (272), Expect = 1e-24
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L L +L +KE+LR++ VP I+R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 96 FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LA 152
FFY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
Query: 153 AHGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
+ G D I + L+ SLQ+ + D Q+K +++
Sbjct: 183 SEGSACLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 113 bits (271), Expect = 1e-24
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASVLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L L +L +KE+LR++ VP I+R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVISRHVTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 96 FFYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LA 152
FFY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
Query: 153 AHGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
+ G D I + L+ SLQ+ + D Q+K +++
Sbjct: 183 SEGSACLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 112 bits (270), Expect = 2e-24
Identities = 69/224 (30%), Positives = 121/224 (54%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L +L +L IKE+LR++ VPA++R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ +N+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 45.6 bits (103), Expect = 3e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LAA 153
FY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA+
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLAS 183
Query: 154 HGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
G D I + L+ SLQ+ + D Q+K +++
Sbjct: 184 EGSARLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 112 bits (270), Expect = 2e-24
Identities = 69/224 (30%), Positives = 121/224 (54%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L +L +L IKE+LR++ VPA++R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ +N+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGIWLRVE 517
Score = 44.4 bits (100), Expect = 7e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LAA 153
FY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA+
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLAS 183
Query: 154 HGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
G D I + L+ SLQ+ + D Q+K +++
Sbjct: 184 KGYARLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 112 bits (269), Expect = 2e-24
Identities = 68/224 (30%), Positives = 120/224 (53%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQ 353
Query: 235 IYDEILAEVGDNK--DVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D + ++ D L +L +L IKE+LR++ VP I+R D L +
Sbjct: 354 CRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + +H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L H+++ + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVE 517
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFN---NQGRRLIMQLAA 153
FY F ++G+G+L + W + R+ L PAF IL +M IFN N +LA+
Sbjct: 124 FYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLAS 183
Query: 154 HGPGSFDHHHPILINNLESSLQETI 178
G D I + L+ SLQ+ +
Sbjct: 184 EGSARLDMFEHISLMTLD-SLQKCV 207
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 112 bits (269), Expect = 2e-24
Identities = 63/218 (28%), Positives = 120/218 (55%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + T + ++LK G H++L
Sbjct: 469 VARALTLLRFELLPDPTRTPIPMARLVLKSKNGIHLRL 506
Score = 33.1 bits (72), Expect = 1.8
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG +L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 111 bits (268), Expect = 3e-24
Identities = 69/224 (30%), Positives = 121/224 (54%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L +L +L IKE+LR++ VPA++R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ +N+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 45.6 bits (103), Expect = 3e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LAA 153
FY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA+
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLAS 183
Query: 154 HGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
G D I + L+ SLQ+ + D Q+K +++
Sbjct: 184 EGSARLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 111 bits (268), Expect = 3e-24
Identities = 69/224 (30%), Positives = 121/224 (54%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L +L +L IKE+LR++ VPA++R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ +N+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 45.6 bits (103), Expect = 3e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LAA 153
FY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA+
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLAS 183
Query: 154 HGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
G D I + L+ SLQ+ + D Q+K +++
Sbjct: 184 EGSARLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 111 bits (268), Expect = 3e-24
Identities = 69/224 (30%), Positives = 121/224 (54%), Gaps = 9/224 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQER 353
Query: 235 IYDEILAEVGDN--KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D K++ D L +L +L IKE+LR++ VPA++R D+ L +
Sbjct: 354 CRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + H +P PD + P R+ +N+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAF 473
Query: 347 AMMSMKVLLVHVFRHYKVTGDISNTEHRLGVLLKPATGHHIKLD 390
AM MKV+L ++V D + + ++L+ G ++++
Sbjct: 474 AMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
Score = 45.6 bits (103), Expect = 3e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLIMQ---LAA 153
FY F ++G+G+L + W + R+ L PAF IL +M IFN + + LA+
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLAS 183
Query: 154 HGPGSFDHHHPILINNLESSLQETISLLDFILDQDKSKQFL 194
G D I + L+ SLQ+ + D Q+K +++
Sbjct: 184 EGSARLDMFEHISLMTLD-SLQKCVFSFDSHC-QEKPSEYI 222
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 111 bits (267), Expect = 4e-24
Identities = 62/218 (28%), Positives = 119/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRL 506
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 111 bits (266), Expect = 5e-24
Identities = 66/198 (33%), Positives = 109/198 (55%), Gaps = 9/198 (4%)
Query: 176 ETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQK 234
+T+ +D +L +D+ + L+DE+IR + D F+ DT+A+ L ++L + +PE Q++
Sbjct: 294 KTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQ 353
Query: 235 IYDEILAEVGDNK--DVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YT 291
E+ + D + ++ D L +L +L IKE+LR++ VP I+R D L +
Sbjct: 354 CRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRV 413
Query: 292 IPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVY 346
IPKG I + +H +P PD + P R+ EN+ F PFS G RNCIG+ +
Sbjct: 414 IPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAF 473
Query: 347 AMMSMKVLLVHVFRHYKV 364
AM MKV+L H+++
Sbjct: 474 AMAEMKVVLALTLLHFRI 491
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFN---NQGRRLIMQLAA 153
FY F ++G+G+L + W + R+ L PAF IL +M IFN N +LA+
Sbjct: 124 FYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLAS 183
Query: 154 HGPGSFDHHHPILINNLESSLQETI 178
G D I + L+ SLQ+ +
Sbjct: 184 EGSARLDMFEHISLMTLD-SLQKCV 207
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 110 bits (265), Expect = 7e-24
Identities = 62/218 (28%), Positives = 118/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRL 506
Score = 33.9 bits (74), Expect = 1.0
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ +K Y F +IG +L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDSKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 519
Score = 110 bits (265), Expect = 7e-24
Identities = 62/218 (28%), Positives = 118/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRL 506
Score = 34.3 bits (75), Expect = 0.76
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 NDILKPYVGLMADSVRVML 170
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 110 bits (265), Expect = 7e-24
Identities = 62/218 (28%), Positives = 118/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VARALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRL 506
Score = 33.9 bits (74), Expect = 1.0
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPRIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 NDILKPYVGLMADSVRVML 170
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 110 bits (264), Expect = 1e-23
Identities = 62/218 (28%), Positives = 119/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRL 506
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 110 bits (264), Expect = 1e-23
Identities = 62/218 (28%), Positives = 119/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRL 506
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 110 bits (264), Expect = 1e-23
Identities = 62/218 (28%), Positives = 119/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRL 506
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 110 bits (264), Expect = 1e-23
Identities = 62/218 (28%), Positives = 119/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRL 506
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 109 bits (263), Expect = 1e-23
Identities = 67/216 (31%), Positives = 114/216 (52%), Gaps = 10/216 (4%)
Query: 181 LDFILD--QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDE 238
LD +L + +K F ++ +++ ++ F+ A DT+++A+ ++L + YPE QQ+ DE
Sbjct: 285 LDILLSAKSENTKDF-SEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDE 343
Query: 239 ILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSS 297
I +GD +T + L ++ Y IKE LR+Y+ V I+R D + + ++P G +
Sbjct: 344 IRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGIT 403
Query: 298 IGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMK 352
+ I + LH +P + D F P R+ EN F PFS G RNCIG+ +A++ K
Sbjct: 404 VFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECK 463
Query: 353 VLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHI 387
V + +K+ D S + V+LK G H+
Sbjct: 464 VAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHV 499
Score = 33.1 bits (72), Expect = 1.8
Identities = 19/86 (22%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKGFF-YDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP ++ V DPD + ++ K + +++G G++ WK+ R+ + P F
Sbjct: 85 GPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLIMQLAAH 154
IL F+ + + R ++ + H
Sbjct: 145 NISILKIFITMMSESVRMMLNKWEEH 170
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 109 bits (263), Expect = 1e-23
Identities = 67/216 (31%), Positives = 114/216 (52%), Gaps = 10/216 (4%)
Query: 181 LDFILD--QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDE 238
LD +L + +K F ++ +++ ++ F+ A DT+++A+ ++L + YPE QQ+ DE
Sbjct: 285 LDILLSAKSENTKDF-SEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDE 343
Query: 239 ILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSS 297
I +GD +T + L ++ Y IKE LR+Y+ V I+R D + + ++P G +
Sbjct: 344 IRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGIT 403
Query: 298 IGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMK 352
+ I + LH +P + D F P R+ EN F PFS G RNCIG+ +A++ K
Sbjct: 404 VFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECK 463
Query: 353 VLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHI 387
V + +K+ D S + V+LK G H+
Sbjct: 464 VAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHV 499
Score = 33.1 bits (72), Expect = 1.8
Identities = 19/86 (22%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKGFF-YDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP ++ V DPD + ++ K + +++G G++ WK+ R+ + P F
Sbjct: 85 GPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLIMQLAAH 154
IL F+ + + R ++ + H
Sbjct: 145 NISILKIFITMMSESVRMMLNKWEEH 170
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 109 bits (263), Expect = 1e-23
Identities = 67/216 (31%), Positives = 114/216 (52%), Gaps = 10/216 (4%)
Query: 181 LDFILD--QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDE 238
LD +L + +K F ++ +++ ++ F+ A DT+++A+ ++L + YPE QQ+ DE
Sbjct: 285 LDILLSAKSENTKDF-SEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDE 343
Query: 239 ILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSS 297
I +GD +T + L ++ Y IKE LR+Y+ V I+R D + + ++P G +
Sbjct: 344 IRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGIT 403
Query: 298 IGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMK 352
+ I + LH +P + D F P R+ EN F PFS G RNCIG+ +A++ K
Sbjct: 404 VFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECK 463
Query: 353 VLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHI 387
V + +K+ D S + V+LK G H+
Sbjct: 464 VAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHV 499
Score = 33.1 bits (72), Expect = 1.8
Identities = 19/86 (22%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKGFF-YDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP ++ V DPD + ++ K + +++G G++ WK+ R+ + P F
Sbjct: 85 GPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLIMQLAAH 154
IL F+ + + R ++ + H
Sbjct: 145 NISILKIFITMMSESVRMMLNKWEEH 170
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 109 bits (263), Expect = 1e-23
Identities = 67/216 (31%), Positives = 114/216 (52%), Gaps = 10/216 (4%)
Query: 181 LDFILD--QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDE 238
LD +L + +K F ++ +++ ++ F+ A DT+++A+ ++L + YPE QQ+ DE
Sbjct: 285 LDILLSAKSENTKDF-SEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDE 343
Query: 239 ILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSS 297
I +GD +T + L ++ Y IKE LR+Y+ V I+R D + + ++P G +
Sbjct: 344 IRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGIT 403
Query: 298 IGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMK 352
+ I + LH +P + D F P R+ EN F PFS G RNCIG+ +A++ K
Sbjct: 404 VFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECK 463
Query: 353 VLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHI 387
V + +K+ D S + V+LK G H+
Sbjct: 464 VAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHV 499
Score = 33.1 bits (72), Expect = 1.8
Identities = 19/86 (22%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 71 GPIKVYI-VADPDDSAVVATNCLAKGFF-YDFSNAYIGNGILCAKLPLWKQQRKALNPAF 128
GP ++ V DPD + ++ K + +++G G++ WK+ R+ + P F
Sbjct: 85 GPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGF 144
Query: 129 KQQILNNFMDIFNNQGRRLIMQLAAH 154
IL F+ + + R ++ + H
Sbjct: 145 NISILKIFITMMSESVRMMLNKWEEH 170
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 108 bits (260), Expect = 3e-23
Identities = 61/218 (27%), Positives = 119/218 (54%), Gaps = 6/218 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR++ VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 468
Query: 353 VLLVHVFRHYKVTGDISNTEHRLG-VLLKPATGHHIKL 389
V +++ D + + ++LK G H++L
Sbjct: 469 VATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRL 506
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 108 bits (260), Expect = 3e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 283 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPEHQHRCR 342
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 343 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 402
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 403 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 462
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 463 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 283 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 342
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 343 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 402
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 403 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 462
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 463 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 283 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 342
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 343 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 402
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 403 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 462
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 463 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 283 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 342
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 343 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 402
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 403 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 462
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 463 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 284 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 343
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 344 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 403
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 404 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 463
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 464 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 503
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 269 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 328
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 329 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 388
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 389 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 448
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 449 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 488
Score = 34.7 bits (76), Expect = 0.58
Identities = 14/43 (32%), Positives = 22/43 (51%)
Query: 106 GNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
G G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 150
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 284 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 343
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 344 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 403
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 404 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 463
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 464 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 503
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 283 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 342
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 343 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 402
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 403 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 462
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 463 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 269 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 328
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 329 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 388
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 389 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 448
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 449 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 488
Score = 34.7 bits (76), Expect = 0.58
Identities = 14/43 (32%), Positives = 22/43 (51%)
Query: 106 GNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
G G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 150
>AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 284 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 343
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 344 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 403
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 404 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 463
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 464 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 503
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 283 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 342
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 343 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 402
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 403 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 462
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 463 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 283 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 342
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 343 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 402
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 403 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 462
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 463 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 284 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 343
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 344 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 403
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 404 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 463
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 464 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 503
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 107 bits (258), Expect = 5e-23
Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + + L + YPE Q +
Sbjct: 269 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR 328
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 329 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 388
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 389 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 448
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 449 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 488
Score = 34.7 bits (76), Expect = 0.58
Identities = 14/43 (32%), Positives = 22/43 (51%)
Query: 106 GNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
G G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 150
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 107 bits (257), Expect = 7e-23
Identities = 57/195 (29%), Positives = 108/195 (55%), Gaps = 5/195 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 468
Query: 353 VLLVHVFRHYKVTGD 367
V +++ D
Sbjct: 469 VATALTLLRFELLPD 483
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 106 bits (255), Expect = 1e-22
Identities = 66/220 (30%), Positives = 111/220 (50%), Gaps = 8/220 (3%)
Query: 178 ISLLDFILD-QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L +D+ L+D ++R ++D F+ DT+ + + L + YPE Q +
Sbjct: 283 LDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPEHQHRCR 342
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLK-LKNYTIPKG 295
+E+ +GD D L K+ YL IKE+ R+Y VP + R+ + + ++P G
Sbjct: 343 EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAG 402
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
S I + + LH++ PD F R+ TEN + F PFS G RNCIG+ +AM
Sbjct: 403 SLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 462
Query: 351 MKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKL 389
MKV+ ++ + D S ++ ++L+ G H+ L
Sbjct: 463 MKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHL 502
Score = 42.3 bits (95), Expect = 0.003
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 98 YDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFNNQGRRLI 148
YDF +IG G+L + P W Q RK L P F +L ++ +F R ++
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML 165
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 105 bits (253), Expect = 2e-22
Identities = 56/181 (30%), Positives = 104/181 (57%), Gaps = 5/181 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 290 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 349
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 350 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 409
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKRNCIGKVYAMMSMK 352
+ + + LH +P+ P+ F P R+ ++ + F PFS G RNCIGK +AM +K
Sbjct: 410 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 469
Query: 353 V 353
V
Sbjct: 470 V 470
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 103 bits (248), Expect = 8e-22
Identities = 66/232 (28%), Positives = 125/232 (53%), Gaps = 12/232 (5%)
Query: 170 LESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
L++ +T+ +D +L +D+ + L+DE+IR + D F+ DT+++ + ++L + Y
Sbjct: 295 LKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKY 354
Query: 229 PEVQQKIYDEILAEVGDNKDVTK---DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDL 285
PE Q+K +EI EV +++ + D L +L + IKE+LR Y V ++R+ D+
Sbjct: 355 PEYQEKCREEI-QEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDI 413
Query: 286 KLKN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKR 339
KL + IPKG + + H +P PD+ + P R+ +N + PFS G R
Sbjct: 414 KLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPR 473
Query: 340 NCIGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKLD 390
NCIG+ +AM ++V++ ++++ D + R ++L+ G +K++
Sbjct: 474 NCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
Score = 44.4 bits (100), Expect = 7e-04
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFN 141
FY F ++G+G+L +K W + R+ L PAF IL +M IFN
Sbjct: 132 FYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN 176
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 103 bits (248), Expect = 8e-22
Identities = 66/232 (28%), Positives = 125/232 (53%), Gaps = 12/232 (5%)
Query: 170 LESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
L++ +T+ +D +L +D+ + L+DE+IR + D F+ DT+++ + ++L + Y
Sbjct: 295 LKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKY 354
Query: 229 PEVQQKIYDEILAEVGDNKDVTK---DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDL 285
PE Q+K +EI EV +++ + D L +L + IKE+LR Y V ++R+ D+
Sbjct: 355 PEYQEKCREEI-QEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDI 413
Query: 286 KLKN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKR 339
KL + IPKG + + H +P PD+ + P R+ +N + PFS G R
Sbjct: 414 KLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPR 473
Query: 340 NCIGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKLD 390
NCIG+ +AM ++V++ ++++ D + R ++L+ G +K++
Sbjct: 474 NCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
Score = 44.4 bits (100), Expect = 7e-04
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFN 141
FY F ++G+G+L +K W + R+ L PAF IL +M IFN
Sbjct: 132 FYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN 176
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 103 bits (248), Expect = 8e-22
Identities = 66/232 (28%), Positives = 125/232 (53%), Gaps = 12/232 (5%)
Query: 170 LESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
L++ +T+ +D +L +D+ + L+DE+IR + D F+ DT+++ + ++L + Y
Sbjct: 295 LKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKY 354
Query: 229 PEVQQKIYDEILAEVGDNKDVTK---DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDL 285
PE Q+K +EI EV +++ + D L +L + IKE+LR Y V ++R+ D+
Sbjct: 355 PEYQEKCREEI-QEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDI 413
Query: 286 KLKN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKR 339
KL + IPKG + + H +P PD+ + P R+ +N + PFS G R
Sbjct: 414 KLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPR 473
Query: 340 NCIGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKLD 390
NCIG+ +AM ++V++ ++++ D + R ++L+ G +K++
Sbjct: 474 NCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
Score = 44.4 bits (100), Expect = 7e-04
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFN 141
FY F ++G+G+L +K W + R+ L PAF IL +M IFN
Sbjct: 132 FYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN 176
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 103 bits (248), Expect = 8e-22
Identities = 66/232 (28%), Positives = 125/232 (53%), Gaps = 12/232 (5%)
Query: 170 LESSLQETISLLD-FILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
L++ +T+ +D +L +D+ + L+DE+IR + D F+ DT+++ + ++L + Y
Sbjct: 295 LKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKY 354
Query: 229 PEVQQKIYDEILAEVGDNKDVTK---DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDL 285
PE Q+K +EI EV +++ + D L +L + IKE+LR Y V ++R+ D+
Sbjct: 355 PEYQEKCREEI-QEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDI 413
Query: 286 KLKN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKR 339
KL + IPKG + + H +P PD+ + P R+ +N + PFS G R
Sbjct: 414 KLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPR 473
Query: 340 NCIGKVYAMMSMKVLLVHVFRHYKVTGDISNTEHRL-GVLLKPATGHHIKLD 390
NCIG+ +AM ++V++ ++++ D + R ++L+ G +K++
Sbjct: 474 NCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
Score = 44.4 bits (100), Expect = 7e-04
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 97 FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFKQQILNNFMDIFN 141
FY F ++G+G+L +K W + R+ L PAF IL +M IFN
Sbjct: 132 FYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN 176
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 100 bits (240), Expect = 8e-21
Identities = 63/201 (31%), Positives = 107/201 (53%), Gaps = 7/201 (3%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGS 227
N LE Q+ + DF+ D + L+ +E+ + +A+ +T+A +L+++L +
Sbjct: 287 NRLEKYSQQPSA--DFLCDIYHQNR-LSKKELYAAVTELQLAAVETTANSLMWILYNLSR 343
Query: 228 YPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
P+VQQK+ EI + + +N+ ++ L + YL+A +KE++R+ VP R D L
Sbjct: 344 NPQVQQKLLKEIQSVLPENQRPREEDLRNMPYLKACLKESMRLTPGVPFTTRTLDKATVL 403
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF--TENLNVFA--PFSMGKRNCIG 343
Y +PKG+ + + L D+ QFRPERW E +N FA PF +GKR CIG
Sbjct: 404 GEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIG 463
Query: 344 KVYAMMSMKVLLVHVFRHYKV 364
+ A + + + L + R Y +
Sbjct: 464 RRLAELQLHLALCWIVRKYDI 484
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 100 bits (240), Expect = 8e-21
Identities = 58/180 (32%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEV--GDNKD 248
++ L + I + L+A DT + L + L + +PEVQ ++ EI A + G +
Sbjct: 299 REELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAY 358
Query: 249 VTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ VL +L L+AV+KE LR+Y VVP +R D D+ + +Y IPK + + + +
Sbjct: 359 PSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRD 418
Query: 309 PQWGPDAHQFRPERWFTE--NLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P P+ + FRP RW E + FA PF GKR+C+G+ A + +++ L + H++V
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 99 bits (238), Expect = 1e-20
Identities = 63/201 (31%), Positives = 106/201 (52%), Gaps = 7/201 (3%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGS 227
N LE Q+ + DF+ D + L+ +E+ + +A+ +T+A +L+++L +
Sbjct: 31 NRLEKYSQQPSA--DFLCDIYHQNR-LSKKELYAAVTELQLAAVETTANSLMWILYNLSR 87
Query: 228 YPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
P+VQQK+ EI + + +N+ + L + YL+A +KE++R+ VP R D L
Sbjct: 88 NPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVL 147
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF--TENLNVFA--PFSMGKRNCIG 343
Y +PKG+ + + L D+ QFRPERW E +N FA PF +GKR CIG
Sbjct: 148 GEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIG 207
Query: 344 KVYAMMSMKVLLVHVFRHYKV 364
+ A + + + L + R Y +
Sbjct: 208 RRLAELQLHLALCWIVRKYDI 228
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 99 bits (238), Expect = 1e-20
Identities = 63/201 (31%), Positives = 106/201 (52%), Gaps = 7/201 (3%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGS 227
N LE Q+ + DF+ D + L+ +E+ + +A+ +T+A +L+++L +
Sbjct: 146 NRLEKYSQQPSA--DFLCDIYHQNR-LSKKELYAAVTELQLAAVETTANSLMWILYNLSR 202
Query: 228 YPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
P+VQQK+ EI + + +N+ + L + YL+A +KE++R+ VP R D L
Sbjct: 203 NPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVL 262
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF--TENLNVFA--PFSMGKRNCIG 343
Y +PKG+ + + L D+ QFRPERW E +N FA PF +GKR CIG
Sbjct: 263 GEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIG 322
Query: 344 KVYAMMSMKVLLVHVFRHYKV 364
+ A + + + L + R Y +
Sbjct: 323 RRLAELQLHLALCWIVRKYDI 343
>AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 99 bits (238), Expect = 1e-20
Identities = 63/201 (31%), Positives = 106/201 (52%), Gaps = 7/201 (3%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGS 227
N LE Q+ + DF+ D + L+ +E+ + +A+ +T+A +L+++L +
Sbjct: 288 NRLEKYSQQPSA--DFLCDIYHQNR-LSKKELYAAVTELQLAAVETTANSLMWILYNLSR 344
Query: 228 YPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
P+VQQK+ EI + + +N+ + L + YL+A +KE++R+ VP R D L
Sbjct: 345 NPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVL 404
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF--TENLNVFA--PFSMGKRNCIG 343
Y +PKG+ + + L D+ QFRPERW E +N FA PF +GKR CIG
Sbjct: 405 GEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIG 464
Query: 344 KVYAMMSMKVLLVHVFRHYKV 364
+ A + + + L + R Y +
Sbjct: 465 RRLAELQLHLALCWIVRKYDI 485
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 99 bits (238), Expect = 1e-20
Identities = 63/201 (31%), Positives = 106/201 (52%), Gaps = 7/201 (3%)
Query: 168 NNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGS 227
N LE Q+ + DF+ D + L+ +E+ + +A+ +T+A +L+++L +
Sbjct: 146 NRLEKYSQQPSA--DFLCDIYHQNR-LSKKELYAAVTELQLAAVETTANSLMWILYNLSR 202
Query: 228 YPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKL 287
P+VQQK+ EI + + +N+ + L + YL+A +KE++R+ VP R D L
Sbjct: 203 NPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVL 262
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF--TENLNVFA--PFSMGKRNCIG 343
Y +PKG+ + + L D+ QFRPERW E +N FA PF +GKR CIG
Sbjct: 263 GEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIG 322
Query: 344 KVYAMMSMKVLLVHVFRHYKV 364
+ A + + + L + R Y +
Sbjct: 323 RRLAELQLHLALCWIVRKYDI 343
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 98.3 bits (234), Expect = 4e-20
Identities = 51/157 (32%), Positives = 90/157 (57%), Gaps = 5/157 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQF-----LTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
E LQ + I+D SK+ L+D E+ Q I + A++DT++T L +++ +
Sbjct: 122 ELGLQHRVDFFQQIIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYEL 181
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDL 285
++P+VQQK+ +EI A + + VT D L ++ YL+ V+ ETLR++ VV + R D+
Sbjct: 182 ATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDI 241
Query: 286 KLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPER 322
++ IPKG ++ + + LH P++ + +F PER
Sbjct: 242 EINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 278
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 97.9 bits (233), Expect = 5e-20
Identities = 52/185 (28%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 97.9 bits (233), Expect = 5e-20
Identities = 52/185 (28%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 233 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 291
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 292 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 351
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 352 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 411
Query: 360 RHYKV 364
+++++
Sbjct: 412 QNFRL 416
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 97.9 bits (233), Expect = 5e-20
Identities = 52/185 (28%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 97.9 bits (233), Expect = 5e-20
Identities = 52/185 (28%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 97.9 bits (233), Expect = 5e-20
Identities = 52/185 (28%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 97.9 bits (233), Expect = 5e-20
Identities = 52/185 (28%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 97.9 bits (233), Expect = 5e-20
Identities = 52/185 (28%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 97.9 bits (233), Expect = 5e-20
Identities = 52/185 (28%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 185 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 243
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 244 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 302
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 303 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 360
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 361 VMMKAILVTLLRRFHV 376
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 185 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 243
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 244 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 302
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 303 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 360
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 361 VMMKAILVTLLRRFHV 376
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 97.1 bits (231), Expect = 1e-19
Identities = 61/196 (31%), Positives = 105/196 (53%), Gaps = 6/196 (3%)
Query: 171 ESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPE 230
E L+E + ++ +K LT E + + I LIA+ DT + +L ++L ++ +P
Sbjct: 269 EEKLEECMDFATELILAEKRGD-LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPN 327
Query: 231 VQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNY 290
V++ I EI +G+ +D+ D + KL +E I E++R VV + RK D + Y
Sbjct: 328 VEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGY 386
Query: 291 TIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENL--NVFAPFSMGKRNCIGKVYAM 348
+ KG++I + +G +H+ ++ P ++F E F +N+ F PF G R C GK AM
Sbjct: 387 PVKKGTNIILNIGRMHR-LEFFPKPNEFTLEN-FAKNVPYRYFQPFGFGPRGCAGKYIAM 444
Query: 349 MSMKVLLVHVFRHYKV 364
+ MK +LV + R + V
Sbjct: 445 VMMKAILVTLLRRFHV 460
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 96.3 bits (229), Expect = 2e-19
Identities = 51/185 (27%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F I +T +T L Y ++ +PEV+ ++++EI +G
Sbjct: 274 EKNPNTEFYLKNLVMTTLNLF-IGGTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIGK 332
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 333 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGS 392
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + E + F PFS+GKRNC G+ A M + + V
Sbjct: 393 VLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVM 452
Query: 360 RHYKV 364
+++++
Sbjct: 453 QNFRL 457
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 96.3 bits (229), Expect = 2e-19
Identities = 57/209 (27%), Positives = 109/209 (52%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 253 HHQSLDPNCPRDLTDCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 311
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV++E R ++VP+ + +
Sbjct: 312 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVREIQRFITLVPSNLPHE 371
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 372 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 431
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A M + +LL + +H+ +
Sbjct: 432 TGKRVCAGEGLARMELFLLLCAILQHFNL 460
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 96.3 bits (229), Expect = 2e-19
Identities = 46/136 (33%), Positives = 84/136 (61%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
+ KS + L+D E+ Q I + A++DT++T L +++ + ++P+VQQK+ +EI A + +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
VT D L ++ YL+ V+ ETLR++ VV + R D+++ IPKG ++ + + LH
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALH 402
Query: 307 QHPQWGPDAHQFRPER 322
P++ + +F PER
Sbjct: 403 HDPKYWTEPEKFCPER 418
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 95.1 bits (226), Expect = 4e-19
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 253 HHQSLDPNCPRDLTDCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 311
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV+ E R ++VP+ + +
Sbjct: 312 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 371
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 372 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 431
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A M + +LL + +H+ +
Sbjct: 432 TGKRVCAGEGLARMELFLLLCAILQHFNL 460
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 95.1 bits (226), Expect = 4e-19
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 253 HHQSLDPNCPRDLTDCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 311
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV+ E R ++VP+ + +
Sbjct: 312 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 371
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 372 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 431
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A M + +LL + +H+ +
Sbjct: 432 TGKRVCAGEGLARMELFLLLCAILQHFNL 460
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 95.1 bits (226), Expect = 4e-19
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 253 HHQSLDPNCPRDLTDCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 311
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV+ E R ++VP+ + +
Sbjct: 312 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 371
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 372 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 431
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A M + +LL + +H+ +
Sbjct: 432 TGKRVCAGEGLARMELFLLLCAILQHFNL 460
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 95.1 bits (226), Expect = 4e-19
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 253 HHQSLDPNCPRDLADCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 311
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV+ E R ++VP+ + +
Sbjct: 312 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 371
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 372 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 431
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A M + +LL + +H+ +
Sbjct: 432 TGKRVCAGEGLARMELFLLLCAILQHFNL 460
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 95.1 bits (226), Expect = 4e-19
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 253 HHQSLDPNCPRDLTDCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 311
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV+ E R ++VP+ + +
Sbjct: 312 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 371
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 372 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 431
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A M + +LL + +H+ +
Sbjct: 432 TGKRVCAGEGLARMELFLLLCAILQHFNL 460
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 95.1 bits (226), Expect = 4e-19
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 253 HHQSLDPNCPRDLTDCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 311
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV+ E R ++VP+ + +
Sbjct: 312 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 371
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 372 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 431
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A M + +LL + +H+ +
Sbjct: 432 TGKRVCAGEGLARMELFLLLCAILQHFNL 460
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 95.1 bits (226), Expect = 4e-19
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 222 HHQSLDPNCPRDLTDCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 280
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV+ E R ++VP+ + +
Sbjct: 281 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 340
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 341 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 400
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A M + +LL + +H+ +
Sbjct: 401 TGKRVCAGEGLARMELFLLLCAILQHFNL 429
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 94.3 bits (224), Expect = 7e-19
Identities = 51/185 (27%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F IA +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLMMSTLNLF-IAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + + + F PFS+GKR C G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 94.3 bits (224), Expect = 7e-19
Identities = 51/185 (27%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F IA +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLMMSTLNLF-IAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P + + F P+ + + + F PFS+GKR C G+ A M + + V
Sbjct: 398 VLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 92.7 bits (220), Expect = 2e-18
Identities = 56/209 (26%), Positives = 107/209 (51%), Gaps = 7/209 (3%)
Query: 162 HHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYL 221
HH L N L + + L++ ++ +++ T + I + A +T++T L Y
Sbjct: 253 HHQSLDPNCPRDLTDCL-LVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYG 311
Query: 222 LTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARK 280
L ++ YPE+++K+++EI +G ++ ++ Y++AV+ E R ++VP+ + +
Sbjct: 312 LLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 371
Query: 281 TDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTEN-----LNVFAPFS 335
D + Y IPKG+ + L ++ Q PD +F+PE + EN + F PFS
Sbjct: 372 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFS 431
Query: 336 MGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
GKR C G+ A + +LL + +H+ +
Sbjct: 432 TGKRVCAGEGLARTELFLLLCAILQHFNL 460
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 91.5 bits (217), Expect = 5e-18
Identities = 51/185 (27%), Positives = 102/185 (55%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F IA +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLMMSTLNLF-IAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + ++ + F P+ + E + F PFS+ KRNC G+ A M + + V
Sbjct: 398 VLRDLRFFSNPRDFNPQHFLGEKGQFKKRDAFVPFSIRKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 91.1 bits (216), Expect = 6e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 4/159 (2%)
Query: 210 SFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLR 269
S DT+ L+ L + P VQQ + E LA + + +L L A +KETLR
Sbjct: 315 SMDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLR 374
Query: 270 MYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFT---E 326
+Y V + R DL L+NY IP G+ + + L +L ++P P ++ P+RW
Sbjct: 375 LYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGS 434
Query: 327 NLNVF-APFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
N + PF G R C+G+ A M +LL HV +H +V
Sbjct: 435 GRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 90.6 bits (215), Expect = 8e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 4/159 (2%)
Query: 210 SFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLR 269
S DT+ L+ L + P VQQ + E LA + + +L L A +KETLR
Sbjct: 315 SVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLR 374
Query: 270 MYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFT---E 326
+Y V + R DL L+NY IP G+ + + L +L ++P P ++ P+RW
Sbjct: 375 LYPVGLFLERVVSSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGS 434
Query: 327 NLNVF-APFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
N + PF G R C+G+ A M +LL HV +H +V
Sbjct: 435 GRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 90.6 bits (215), Expect = 8e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 4/159 (2%)
Query: 210 SFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLR 269
S DT+ L+ L + P VQQ + E LA + + +L L A +KETLR
Sbjct: 315 SVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLR 374
Query: 270 MYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFT---E 326
+Y V + R DL L+NY IP G+ + + L +L ++P P ++ P+RW
Sbjct: 375 LYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGS 434
Query: 327 NLNVF-APFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
N + PF G R C+G+ A M +LL HV +H +V
Sbjct: 435 GRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 90.6 bits (215), Expect = 8e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 4/159 (2%)
Query: 210 SFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLR 269
S DT+ L+ L + P VQQ + E LA + + +L L A +KETLR
Sbjct: 315 SVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLR 374
Query: 270 MYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFT---E 326
+Y V + R DL L+NY IP G+ + + L +L ++P P ++ P+RW
Sbjct: 375 LYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGS 434
Query: 327 NLNVF-APFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
N + PF G R C+G+ A M +LL HV +H +V
Sbjct: 435 GRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 90.6 bits (215), Expect = 8e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 4/159 (2%)
Query: 210 SFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLR 269
S DT+ L+ L + P VQQ + E LA + + +L L A +KETLR
Sbjct: 386 SVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLR 445
Query: 270 MYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFT---E 326
+Y V + R DL L+NY IP G+ + + L +L ++P P ++ P+RW
Sbjct: 446 LYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGS 505
Query: 327 NLNVF-APFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
N + PF G R C+G+ A M +LL HV +H +V
Sbjct: 506 GRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 544
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 90.2 bits (214), Expect = 1e-17
Identities = 51/185 (27%), Positives = 101/185 (54%), Gaps = 7/185 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F IA +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLMMSTLNLF-IAGTETVSTTLHYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EAVI E R V+P ++AR+ D K +++ +PKG + MLG+
Sbjct: 338 NRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGIEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + ++ + F P+ + E + F PFS+ KRNC G+ A M + + V
Sbjct: 398 VLRDLRFFSNPRDFNPQHFLGEKGQFKKRDAFVPFSIRKRNCFGEGLARMELFLFFTTVM 457
Query: 360 RHYKV 364
+++++
Sbjct: 458 QNFRL 462
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 88.6 bits (210), Expect = 3e-17
Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 25/252 (9%)
Query: 131 QILNNF---MDIFNNQGRRLIMQLAAHGPGSFD----HHHPILINNLESSLQETISLLDF 183
QI NNF +D F +L+ LA + H + INN + F
Sbjct: 192 QICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID------CF 245
Query: 184 ILDQDKSKQFLTDEEIREQIDI----FLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
++ +K KQ E E + I L A +T++T L Y L ++ +PEV K+ +EI
Sbjct: 246 LIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEI 305
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSI 298
VG N+ + Y +AV+ E R ++P ++ D+K +NY IPKG++I
Sbjct: 306 ERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTI 365
Query: 299 GIML-GTLHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMK 352
L LH + ++ P+ F P + E N F PFS GKR C+G+ A M +
Sbjct: 366 LTSLTSVLHDNKEF-PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELF 424
Query: 353 VLLVHVFRHYKV 364
+ L + +++ +
Sbjct: 425 LFLTFILQNFNL 436
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 88.6 bits (210), Expect = 3e-17
Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 25/252 (9%)
Query: 131 QILNNF---MDIFNNQGRRLIMQLAAHGPGSFD----HHHPILINNLESSLQETISLLDF 183
QI NNF +D F +L+ LA + H + INN + F
Sbjct: 214 QICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID------CF 267
Query: 184 ILDQDKSKQFLTDEEIREQIDI----FLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
++ +K KQ E E + I L A +T++T L Y L ++ +PEV K+ +EI
Sbjct: 268 LIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEI 327
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSI 298
VG N+ + Y +AV+ E R ++P ++ D+K +NY IPKG++I
Sbjct: 328 ERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTI 387
Query: 299 GIML-GTLHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMK 352
L LH + ++ P+ F P + E N F PFS GKR C+G+ A M +
Sbjct: 388 LTSLTSVLHDNKEF-PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELF 446
Query: 353 VLLVHVFRHYKV 364
+ L + +++ +
Sbjct: 447 LFLTFILQNFNL 458
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 88.6 bits (210), Expect = 3e-17
Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 25/252 (9%)
Query: 131 QILNNF---MDIFNNQGRRLIMQLAAHGPGSFD----HHHPILINNLESSLQETISLLDF 183
QI NNF +D F +L+ LA + H + INN + F
Sbjct: 214 QICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID------CF 267
Query: 184 ILDQDKSKQFLTDEEIREQIDI----FLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
++ +K KQ E E + I L A +T++T L Y L ++ +PEV K+ +EI
Sbjct: 268 LIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEI 327
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSI 298
VG N+ + Y +AV+ E R ++P ++ D+K +NY IPKG++I
Sbjct: 328 ERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTI 387
Query: 299 GIML-GTLHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMK 352
L LH + ++ P+ F P + E N F PFS GKR C+G+ A M +
Sbjct: 388 LTSLTSVLHDNKEF-PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELF 446
Query: 353 VLLVHVFRHYKV 364
+ L + +++ +
Sbjct: 447 LFLTFILQNFNL 458
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 88.6 bits (210), Expect = 3e-17
Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 25/252 (9%)
Query: 131 QILNNF---MDIFNNQGRRLIMQLAAHGPGSFD----HHHPILINNLESSLQETISLLDF 183
QI NNF +D F +L+ LA + H + INN + F
Sbjct: 214 QICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID------CF 267
Query: 184 ILDQDKSKQFLTDEEIREQIDI----FLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
++ +K KQ E E + I L A +T++T L Y L ++ +PEV K+ +EI
Sbjct: 268 LIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEI 327
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSI 298
VG N+ + Y +AV+ E R ++P ++ D+K +NY IPKG++I
Sbjct: 328 ERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTI 387
Query: 299 GIML-GTLHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMK 352
L LH + ++ P+ F P + E N F PFS GKR C+G+ A M +
Sbjct: 388 LTSLTSVLHDNKEF-PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELF 446
Query: 353 VLLVHVFRHYKV 364
+ L + +++ +
Sbjct: 447 LFLTFILQNFNL 458
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 88.2 bits (209), Expect = 4e-17
Identities = 59/212 (27%), Positives = 104/212 (49%), Gaps = 10/212 (4%)
Query: 160 DHHHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALI 219
+H + +NN + + ++ D KS +F + + D+ L A +T++T L
Sbjct: 116 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKS-EFTIENLVITAADL-LGAGTETTSTTLR 173
Query: 220 YLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIA 278
Y L ++ +PEV K+ +EI VG N+ + Y +AV+ E R ++P ++
Sbjct: 174 YALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLP 233
Query: 279 RKTDIDLKLKNYTIPKGSSIGIML-GTLHQHPQWGPDAHQFRPERWFTE-----NLNVFA 332
D+K +NY IPKG++I L LH + ++ P+ F P + E N F
Sbjct: 234 HAVTCDIKFRNYLIPKGTTILTSLTSVLHDNKEF-PNPEMFDPRHFLDEGGNFKKSNYFM 292
Query: 333 PFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
PFS GKR C+G+ A M + + L + +++ +
Sbjct: 293 PFSAGKRICVGEGLARMELFLFLTFILQNFNL 324
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 88.2 bits (209), Expect = 4e-17
Identities = 57/179 (31%), Positives = 86/179 (48%), Gaps = 6/179 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVT 250
K L+ E I+ S DT+A L+ L + P+VQQ + E LA +
Sbjct: 296 KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHP 355
Query: 251 KDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
+ +L L A +KETLR+Y V + R DL L+NY IP G+ + + L +L ++
Sbjct: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAA 415
Query: 311 WGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P ++ P+RW N + PF G R C+G+ A M +LL HV +H+ V
Sbjct: 416 LFPRPERYNPQRWLDIRGSGRNFH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLV 473
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 88.2 bits (209), Expect = 4e-17
Identities = 60/205 (29%), Positives = 100/205 (48%), Gaps = 15/205 (7%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
+ F + I +D+F A +T++T L + L + YPE+Q+K+ EI +G +
Sbjct: 293 TSSFHEENLICSTLDLFF-AGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQP 351
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ + Y AVI E RM +++P + R+ +D L Y +PKG+ I L LH+
Sbjct: 352 STAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRD 411
Query: 309 P-QWG-PDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVL---LVHV 358
P +W PD F P+ F EN F PFS+GKR C+G+ A + + L+
Sbjct: 412 PTEWATPDT--FNPDH-FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQK 468
Query: 359 FRHYKVTGDISNTEHRLGVLLKPAT 383
F + + + R+G+ + P +
Sbjct: 469 FTFRPPNNEKLSLKFRMGITISPVS 493
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 88.2 bits (209), Expect = 4e-17
Identities = 71/252 (28%), Positives = 116/252 (46%), Gaps = 25/252 (9%)
Query: 131 QILNNF---MDIFNNQGRRLIMQLAAHGPGSFD----HHHPILINNLESSLQETISLLDF 183
QI NNF +D F +L+ LA + H + INN + F
Sbjct: 214 QICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID------CF 267
Query: 184 ILDQDKSKQFLTDEEIREQIDI----FLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI 239
++ +K KQ E E + I L A +T++T L Y L ++ +PEV K+ +EI
Sbjct: 268 LIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEI 327
Query: 240 LAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSI 298
+G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG++I
Sbjct: 328 ERVIGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTI 387
Query: 299 GIML-GTLHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMK 352
L LH + ++ P+ F P + E N F PFS GKR C+G+ A M +
Sbjct: 388 LTSLTSVLHDNKEF-PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELF 446
Query: 353 VLLVHVFRHYKV 364
+ L + +++ +
Sbjct: 447 LFLTFILQNFNL 458
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 88.2 bits (209), Expect = 4e-17
Identities = 57/179 (31%), Positives = 86/179 (48%), Gaps = 6/179 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVT 250
K L+ E I+ S DT+A L+ L + P+VQQ + E LA +
Sbjct: 296 KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHP 355
Query: 251 KDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
+ +L L A +KETLR+Y V + R DL L+NY IP G+ + + L +L ++
Sbjct: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAA 415
Query: 311 WGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P ++ P+RW N + PF G R C+G+ A M +LL HV +H+ V
Sbjct: 416 LFPRPERYNPQRWLDIRGSGRNFH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLV 473
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 88.2 bits (209), Expect = 4e-17
Identities = 60/205 (29%), Positives = 100/205 (48%), Gaps = 15/205 (7%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
+ F + I +D+F A +T++T L + L + YPE+Q+K+ EI +G +
Sbjct: 293 TSSFHEENLICSTLDLFF-AGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQP 351
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ + Y AVI E RM +++P + R+ +D L Y +PKG+ I L LH+
Sbjct: 352 STAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRD 411
Query: 309 P-QWG-PDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVL---LVHV 358
P +W PD F P+ F EN F PFS+GKR C+G+ A + + L+
Sbjct: 412 PTEWATPDT--FNPDH-FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQK 468
Query: 359 FRHYKVTGDISNTEHRLGVLLKPAT 383
F + + + R+G+ + P +
Sbjct: 469 FTFRPPNNEKLSLKFRMGITISPVS 493
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 88.2 bits (209), Expect = 4e-17
Identities = 60/205 (29%), Positives = 100/205 (48%), Gaps = 15/205 (7%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
+ F + I +D+F A +T++T L + L + YPE+Q+K+ EI +G +
Sbjct: 293 TSSFHEENLICSTLDLFF-AGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQP 351
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ + Y AVI E RM +++P + R+ +D L Y +PKG+ I L LH+
Sbjct: 352 STAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRD 411
Query: 309 P-QWG-PDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVL---LVHV 358
P +W PD F P+ F EN F PFS+GKR C+G+ A + + L+
Sbjct: 412 PTEWATPDT--FNPDH-FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQK 468
Query: 359 FRHYKVTGDISNTEHRLGVLLKPAT 383
F + + + R+G+ + P +
Sbjct: 469 FTFRPPNNEKLSLKFRMGITISPVS 493
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 88.2 bits (209), Expect = 4e-17
Identities = 60/205 (29%), Positives = 100/205 (48%), Gaps = 15/205 (7%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
+ F + I +D+F A +T++T L + L + YPE+Q+K+ EI +G +
Sbjct: 293 TSSFHEENLICSTLDLFF-AGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQP 351
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ + Y AVI E RM +++P + R+ +D L Y +PKG+ I L LH+
Sbjct: 352 STAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRD 411
Query: 309 P-QWG-PDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVL---LVHV 358
P +W PD F P+ F EN F PFS+GKR C+G+ A + + L+
Sbjct: 412 PTEWATPDT--FNPDH-FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQK 468
Query: 359 FRHYKVTGDISNTEHRLGVLLKPAT 383
F + + + R+G+ + P +
Sbjct: 469 FTFRPPNNEKLSLKFRMGITISPVS 493
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 87.8 bits (208), Expect = 6e-17
Identities = 62/219 (28%), Positives = 105/219 (47%), Gaps = 11/219 (5%)
Query: 159 FDHHHPILINNLESSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSA 215
FD+ +N +E E + +L Q+K Q F + I D+F A +T++
Sbjct: 66 FDYKDQRFLNLMEK-FNENLRILSSPWIQEKHNQQSEFTVESLIATVTDMFG-AGTETTS 123
Query: 216 TALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP 275
T L Y L ++ YPEV K+ +EI VG N+ + Y +AV+ E R ++P
Sbjct: 124 TTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 183
Query: 276 A-IARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN----- 329
+ D+K KNY IPKG++I L ++ + + P+ F P + ++ N
Sbjct: 184 TNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSD 243
Query: 330 VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKVTGDI 368
F PFS GKR C+G+ A M + + L + +++ + +
Sbjct: 244 YFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 282
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 87.8 bits (208), Expect = 6e-17
Identities = 62/219 (28%), Positives = 105/219 (47%), Gaps = 11/219 (5%)
Query: 159 FDHHHPILINNLESSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSA 215
FD+ +N +E E + +L Q+K Q F + I D+F A +T++
Sbjct: 187 FDYKDQRFLNLMEK-FNENLRILSSPWIQEKHNQQSEFTVESLIATVTDMFG-AGTETTS 244
Query: 216 TALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP 275
T L Y L ++ YPEV K+ +EI VG N+ + Y +AV+ E R ++P
Sbjct: 245 TTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 304
Query: 276 A-IARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN----- 329
+ D+K KNY IPKG++I L ++ + + P+ F P + ++ N
Sbjct: 305 TNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSD 364
Query: 330 VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKVTGDI 368
F PFS GKR C+G+ A M + + L + +++ + +
Sbjct: 365 YFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 403
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 87.8 bits (208), Expect = 6e-17
Identities = 60/205 (29%), Positives = 100/205 (48%), Gaps = 15/205 (7%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
+ F + I +D+F A +T++T L + L + YPE+Q+K+ EI +G +
Sbjct: 293 TSSFHEENLICSTLDLFF-AGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQQP 351
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
+ + Y AVI E RM +++P + R+ +D L Y +PKG+ I L LH+
Sbjct: 352 STAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRD 411
Query: 309 P-QWG-PDAHQFRPERWFTEN-----LNVFAPFSMGKRNCIGKVYAMMSMKVL---LVHV 358
P +W PD F P+ F EN F PFS+GKR C+G+ A + + L+
Sbjct: 412 PTEWATPDT--FNPDH-FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQK 468
Query: 359 FRHYKVTGDISNTEHRLGVLLKPAT 383
F + + + R+G+ + P +
Sbjct: 469 FTFRPPNNEKLSLKFRMGITISPVS 493
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 254 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 312
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 313 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGT 372
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 373 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGME 431
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 432 LFLFLTSILQNFNL 445
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 87.4 bits (207), Expect = 8e-17
Identities = 57/190 (30%), Positives = 96/190 (50%), Gaps = 12/190 (6%)
Query: 185 LDQDKSKQ---FLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILA 241
++Q+K Q F + I D+F A +T++T L Y L ++ +PEV K+ +EI
Sbjct: 151 MEQEKHNQQSEFTVESLIATVTDMFG-AGTETTSTTLRYALLLLLKHPEVTAKVQEEIER 209
Query: 242 EVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGI 300
VG N+ + Y +AV+ E R ++P ++ D+K +NY IPKG++I
Sbjct: 210 VVGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILT 269
Query: 301 ML-GTLHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVL 354
L LH + ++ P+ F P + E N F PFS GKR C+G+ A M + +
Sbjct: 270 SLTSVLHDNKEF-PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLF 328
Query: 355 LVHVFRHYKV 364
L + +++ +
Sbjct: 329 LTFILQNFNL 338
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 160 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 218
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 219 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGT 278
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 279 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGME 337
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 338 LFLFLTSILQNFNL 351
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 262 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 320
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 321 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGT 380
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 381 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGME 439
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 440 LFLFLTSILQNFNL 453
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 262 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 320
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 321 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGT 380
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 381 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGME 439
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 440 LFLFLTSILQNFNL 453
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 264 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 322
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 323 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGT 382
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 383 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGME 441
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 442 LFLFLTSILQNFNL 455
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 267 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 325
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 326 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGT 385
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 386 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGME 444
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 445 LFLFLTSILQNFNL 458
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 267 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 325
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 326 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGT 385
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 386 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGME 444
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 445 LFLFLTSILQNFNL 458
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 87.4 bits (207), Expect = 8e-17
Identities = 47/184 (25%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F A +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLFF-AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y EAVI E R ++P +A + + D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P++ + F P+ + + + F PFS+GKR C G+ A M + + +
Sbjct: 398 VLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIM 457
Query: 360 RHYK 363
++++
Sbjct: 458 QNFR 461
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 87.4 bits (207), Expect = 8e-17
Identities = 47/184 (25%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F A +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLFF-AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y EAVI E R ++P +A + + D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P++ + F P+ + + + F PFS+GKR C G+ A M + + +
Sbjct: 398 VLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIM 457
Query: 360 RHYK 363
++++
Sbjct: 458 QNFR 461
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 87.4 bits (207), Expect = 8e-17
Identities = 47/184 (25%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F A +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLFF-AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y EAVI E R ++P +A + + D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P++ + F P+ + + + F PFS+GKR C G+ A M + + +
Sbjct: 398 VLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIM 457
Query: 360 RHYK 363
++++
Sbjct: 458 QNFR 461
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 87.4 bits (207), Expect = 8e-17
Identities = 47/184 (25%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F A +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLFF-AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y EAVI E R ++P +A + + D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P++ + F P+ + + + F PFS+GKR C G+ A M + + +
Sbjct: 398 VLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIM 457
Query: 360 RHYK 363
++++
Sbjct: 458 QNFR 461
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 267 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 325
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 326 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGT 385
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 386 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGME 444
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 445 LFLFLTSILQNFNL 458
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 87.4 bits (207), Expect = 8e-17
Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 183 FILDQDKSK-----QFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYD 237
F++ +K K +F + +D+F A +T++T L Y L ++ +PEV K+ +
Sbjct: 267 FLMKMEKEKHNQPSEFTIESLENTAVDLFG-AGTETTSTTLRYALLLLLKHPEVTAKVQE 325
Query: 238 EILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGS 296
EI +G N+ + Y +AV+ E R ++P ++ D+K +NY IPKG+
Sbjct: 326 EIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGT 385
Query: 297 SIGIML-GTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMS 350
+I I L LH + ++ P+ F P + E N F PFS GKR C+G+ A M
Sbjct: 386 TILISLTSVLHDNKEF-PNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGME 444
Query: 351 MKVLLVHVFRHYKV 364
+ + L + +++ +
Sbjct: 445 LFLFLTSILQNFNL 458
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 87.4 bits (207), Expect = 8e-17
Identities = 47/184 (25%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F A +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLFF-AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y EAVI E R ++P +A + + D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P++ + F P+ + + + F PFS+GKR C G+ A M + + +
Sbjct: 398 VLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIM 457
Query: 360 RHYK 363
++++
Sbjct: 458 QNFR 461
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 87.0 bits (206), Expect = 1e-16
Identities = 59/204 (28%), Positives = 104/204 (50%), Gaps = 12/204 (5%)
Query: 188 DKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNK 247
D S F + E + + +IA +T+ L + + + YP +Q ++ EI +G N
Sbjct: 290 DPSSTF-SKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNG 348
Query: 248 DVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
+ D K+ Y EAV+ E LR ++VP I T D ++ Y+IPKG+++ L ++H
Sbjct: 349 KPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVH 408
Query: 307 QHPQWGPDAHQFRPERWFTENLNVFA------PFSMGKRNCIGKVYAMMSMKVLLVHVFR 360
++ D F PER F ++ FA PFS+G+R+C+G+ A M M + + +
Sbjct: 409 FDEKYWRDPEVFHPER-FLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQ 467
Query: 361 HYKVTGD---ISNTEHRLGVLLKP 381
+ + + + + RLG+ L+P
Sbjct: 468 RFHLHFPHELVPDLKPRLGMTLQP 491
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 87.0 bits (206), Expect = 1e-16
Identities = 59/204 (28%), Positives = 104/204 (50%), Gaps = 12/204 (5%)
Query: 188 DKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNK 247
D S F + E + + +IA +T+ L + + + YP +Q ++ EI +G N
Sbjct: 290 DPSSTF-SKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNG 348
Query: 248 DVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
+ D K+ Y EAV+ E LR ++VP I T D ++ Y+IPKG+++ L ++H
Sbjct: 349 KPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVH 408
Query: 307 QHPQWGPDAHQFRPERWFTENLNVFA------PFSMGKRNCIGKVYAMMSMKVLLVHVFR 360
++ D F PER F ++ FA PFS+G+R+C+G+ A M M + + +
Sbjct: 409 FDEKYWRDPEVFHPER-FLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQ 467
Query: 361 HYKVTGD---ISNTEHRLGVLLKP 381
+ + + + + RLG+ L+P
Sbjct: 468 RFHLHFPHELVPDLKPRLGMTLQP 491
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 87.0 bits (206), Expect = 1e-16
Identities = 59/204 (28%), Positives = 104/204 (50%), Gaps = 12/204 (5%)
Query: 188 DKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNK 247
D S F + E + + +IA +T+ L + + + YP +Q ++ EI +G N
Sbjct: 290 DPSSTF-SKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNG 348
Query: 248 DVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLH 306
+ D K+ Y EAV+ E LR ++VP I T D ++ Y+IPKG+++ L ++H
Sbjct: 349 KPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVH 408
Query: 307 QHPQWGPDAHQFRPERWFTENLNVFA------PFSMGKRNCIGKVYAMMSMKVLLVHVFR 360
++ D F PER F ++ FA PFS+G+R+C+G+ A M M + + +
Sbjct: 409 FDEKYWRDPEVFHPER-FLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQ 467
Query: 361 HYKVTGD---ISNTEHRLGVLLKP 381
+ + + + + RLG+ L+P
Sbjct: 468 RFHLHFPHELVPDLKPRLGMTLQP 491
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 87.0 bits (206), Expect = 1e-16
Identities = 47/167 (28%), Positives = 92/167 (55%), Gaps = 5/167 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKR 339
+ + + LH +P+ P+ F P R+ ++ + F PFS G R
Sbjct: 409 IMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSR 455
Score = 34.3 bits (75), Expect = 0.76
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 NDILKPYVGLMADSVRVML 170
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 87.0 bits (206), Expect = 1e-16
Identities = 54/178 (30%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + V+ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYVLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 86.6 bits (205), Expect = 1e-16
Identities = 53/185 (28%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Query: 187 QDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDN 246
Q++ +F + + D+ L A +T++T L Y L ++ +PEV K+ +EI +G N
Sbjct: 3 QNQQSEFTIENLVITAADL-LGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRN 61
Query: 247 KDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIML-GT 304
+ + Y +AV+ E R ++P ++ D+K +NY IPKG++I L
Sbjct: 62 RSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSV 121
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
LH + ++ P+ F P + E N F PFS GKR C+G+ A M + + L +
Sbjct: 122 LHDNKEF-PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFIL 180
Query: 360 RHYKV 364
+++ +
Sbjct: 181 QNFNL 185
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 86.2 bits (204), Expect = 2e-16
Identities = 57/179 (31%), Positives = 86/179 (48%), Gaps = 6/179 (3%)
Query: 191 KQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVT 250
K L+ E I+ S DT+A L+ L + P+VQQ + E LA +
Sbjct: 296 KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAASISEHP 355
Query: 251 KDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
+ +L L A +KETLR+Y V + R DL L+NY IP G+ + + L +L ++
Sbjct: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAA 415
Query: 311 WGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKV 364
P ++ P+RW NL+ PF G R C+G+ A M +LL HV + + V
Sbjct: 416 LFPRPERYNPQRWLDIRGSGRNLH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKRFLV 473
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 86.2 bits (204), Expect = 2e-16
Identities = 53/165 (32%), Positives = 87/165 (52%), Gaps = 7/165 (4%)
Query: 204 DIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAV 263
D+F IA DT+ +L++ L + P+VQ+K+++EI +G N+ + ++ Y EA
Sbjct: 348 DLF-IAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEAT 406
Query: 264 IKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPER 322
I E R+ VVP AI T + L+ YTIPKG+ I L ++H+ P F P R
Sbjct: 407 IMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNR 466
Query: 323 WFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHY 362
+ + F PF +GKR C+G+ A M + ++ V + + +
Sbjct: 467 FLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 86.2 bits (204), Expect = 2e-16
Identities = 47/167 (28%), Positives = 93/167 (55%), Gaps = 5/167 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKR 339
+ + + LH +P+ P+ F P R+ ++ + F PFS G R
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSR 455
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 86.2 bits (204), Expect = 2e-16
Identities = 46/184 (25%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F A +T +T L Y ++ +PE++ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLFF-AGTETVSTTLRYGFLLLMKHPELEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y EAVI E R ++P +A + + D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFT-----ENLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ + P++ + F P+ + + + F PFS+GKR C G+ A M + + +
Sbjct: 398 VLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIM 457
Query: 360 RHYK 363
++++
Sbjct: 458 QNFR 461
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 86.2 bits (204), Expect = 2e-16
Identities = 53/165 (32%), Positives = 87/165 (52%), Gaps = 7/165 (4%)
Query: 204 DIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAV 263
D+F IA DT+ +L++ L + P+VQ+K+++EI +G N+ + ++ Y EA
Sbjct: 348 DLF-IAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEAT 406
Query: 264 IKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPER 322
I E R+ VVP AI T + L+ YTIPKG+ I L ++H+ P F P R
Sbjct: 407 IMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNR 466
Query: 323 WFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHY 362
+ + F PF +GKR C+G+ A M + ++ V + + +
Sbjct: 467 FLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 86.2 bits (204), Expect = 2e-16
Identities = 47/167 (28%), Positives = 93/167 (55%), Gaps = 5/167 (2%)
Query: 178 ISLLDFIL-DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIY 236
+ LD +L + ++ L+D+++R ++D F+ DT+A+ + ++L + ++P+ Q++
Sbjct: 289 LDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCR 348
Query: 237 DEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKN-YTIPKG 295
+EI + +GD +T + L ++ Y IKE LR+Y VP I R+ + + ++PKG
Sbjct: 349 EEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 408
Query: 296 SSIGIMLGTLHQHPQWGPDAHQFRPERW---FTENLNVFAPFSMGKR 339
+ + + LH +P+ P+ F P R+ ++ + F PFS G R
Sbjct: 409 IMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSR 455
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 71 GPIKVYIVADPDDSAVVATNCLAKGF-FYDFSNAYIGNGILCAKLPLWKQQRKALNPAFK 129
G ++V + DPD V+ K Y F +IG G+L W Q R+ L PAF
Sbjct: 93 GKVRVQLY-DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 151
Query: 130 QQILNNFMDIFNNQGRRLI 148
IL ++ + + R ++
Sbjct: 152 YDILKPYVGLMADSVRVML 170
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 86.2 bits (204), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPENFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 326 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 383
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 384 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 443
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 444 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHKFR 501
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 259 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 316
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 317 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 376
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 377 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 434
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAEDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 85.4 bits (202), Expect = 3e-16
Identities = 58/206 (28%), Positives = 101/206 (49%), Gaps = 10/206 (4%)
Query: 172 SSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
+S ++ I ++Q+K Q F + I D+F A +T++T L Y L ++ Y
Sbjct: 258 NSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFG-AGTETTSTTLRYGLLLLLKY 316
Query: 229 PEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKL 287
PEV K+ +EI VG N+ + Y +AV+ E R ++P + D+K
Sbjct: 317 PEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKF 376
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCI 342
KNY IPKG++I L ++ + + P+ F P + ++ N F PFS GKR C+
Sbjct: 377 KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
Query: 343 GKVYAMMSMKVLLVHVFRHYKVTGDI 368
G+ A M + + L + +++ + +
Sbjct: 437 GEGLARMELFLFLTTILQNFNLKSQV 462
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 85.4 bits (202), Expect = 3e-16
Identities = 58/206 (28%), Positives = 101/206 (49%), Gaps = 10/206 (4%)
Query: 172 SSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
+S ++ I ++Q+K Q F + I D+F A +T++T L Y L ++ Y
Sbjct: 258 NSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFG-AGTETTSTTLRYGLLLLLKY 316
Query: 229 PEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKL 287
PEV K+ +EI VG N+ + Y +AV+ E R ++P + D+K
Sbjct: 317 PEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKF 376
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCI 342
KNY IPKG++I L ++ + + P+ F P + ++ N F PFS GKR C+
Sbjct: 377 KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
Query: 343 GKVYAMMSMKVLLVHVFRHYKVTGDI 368
G+ A M + + L + +++ + +
Sbjct: 437 GEGLARMELFLFLTTILQNFNLKSQV 462
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 85.4 bits (202), Expect = 3e-16
Identities = 58/206 (28%), Positives = 101/206 (49%), Gaps = 10/206 (4%)
Query: 172 SSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
+S ++ I ++Q+K Q F + I D+F A +T++T L Y L ++ Y
Sbjct: 258 NSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFG-AGTETTSTTLRYGLLLLLKY 316
Query: 229 PEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKL 287
PEV K+ +EI VG N+ + Y +AV+ E R ++P + D+K
Sbjct: 317 PEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKF 376
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCI 342
KNY IPKG++I L ++ + + P+ F P + ++ N F PFS GKR C+
Sbjct: 377 KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
Query: 343 GKVYAMMSMKVLLVHVFRHYKVTGDI 368
G+ A M + + L + +++ + +
Sbjct: 437 GEGLARMELFLFLTTILQNFNLKSQV 462
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 85.4 bits (202), Expect = 3e-16
Identities = 58/206 (28%), Positives = 101/206 (49%), Gaps = 10/206 (4%)
Query: 172 SSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
+S ++ I ++Q+K Q F + I D+F A +T++T L Y L ++ Y
Sbjct: 258 NSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFG-AGTETTSTTLRYGLLLLLKY 316
Query: 229 PEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKL 287
PEV K+ +EI VG N+ + Y +AV+ E R ++P + D+K
Sbjct: 317 PEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKF 376
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCI 342
KNY IPKG++I L ++ + + P+ F P + ++ N F PFS GKR C+
Sbjct: 377 KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
Query: 343 GKVYAMMSMKVLLVHVFRHYKVTGDI 368
G+ A M + + L + +++ + +
Sbjct: 437 GEGLARMELFLFLTTILQNFNLKSQV 462
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 85.4 bits (202), Expect = 3e-16
Identities = 58/206 (28%), Positives = 101/206 (49%), Gaps = 10/206 (4%)
Query: 172 SSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
+S ++ I ++Q+K Q F + I D+F A +T++T L Y L ++ Y
Sbjct: 258 NSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFG-AGTETTSTTLRYGLLLLLKY 316
Query: 229 PEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKL 287
PEV K+ +EI VG N+ + Y +AV+ E R ++P + D+K
Sbjct: 317 PEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKF 376
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCI 342
KNY IPKG++I L ++ + + P+ F P + ++ N F PFS GKR C+
Sbjct: 377 KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
Query: 343 GKVYAMMSMKVLLVHVFRHYKVTGDI 368
G+ A M + + L + +++ + +
Sbjct: 437 GEGLARMELFLFLTTILQNFNLKSQV 462
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 85.4 bits (202), Expect = 3e-16
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
LT +EI Q IFLIA ++ L + ++ + P+ Q+K+ E+ +V K + +
Sbjct: 327 LTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV--DVFKEKHMAPEF 384
Query: 254 LPK---LVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQ 310
L YL+ VI ETLRMY R+ D ++ IP G+ + + +G LH P+
Sbjct: 385 CSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPE 444
Query: 311 WGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYK 363
P F PER+ E + PF G R+C+G ++ +K+ L+HV ++
Sbjct: 445 HWPSPKTFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 85.0 bits (201), Expect = 4e-16
Identities = 58/206 (28%), Positives = 101/206 (49%), Gaps = 10/206 (4%)
Query: 172 SSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
+S ++ I ++Q+K Q F + I D+F A +T++T L Y L ++ Y
Sbjct: 258 NSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFG-AGTETTSTTLRYGLLLLLKY 316
Query: 229 PEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKL 287
PEV K+ +EI VG N+ + Y +AV+ E R ++P + D+K
Sbjct: 317 PEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKF 376
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCI 342
KNY IPKG++I L ++ + + P+ F P + ++ N F PFS GKR C+
Sbjct: 377 KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
Query: 343 GKVYAMMSMKVLLVHVFRHYKVTGDI 368
G+ A M + + L + +++ + +
Sbjct: 437 GEGLARMELFLFLTTILQNFNLKSKV 462
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 85.0 bits (201), Expect = 4e-16
Identities = 49/154 (31%), Positives = 84/154 (54%), Gaps = 9/154 (5%)
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHP 309
T D + ++ YL+ V+ ETLR++ V + R D+++ IPKGS + I LH P
Sbjct: 17 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDP 76
Query: 310 QWGPDAHQFRPERWFTENLN----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKVT 365
++ + +FRPER+ + + ++ PF G RNCIG +A+M+MK+ L+ V +++
Sbjct: 77 KYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 136
Query: 366 GDISNTEHRLGV----LLKPATGHHIKLDKRNKT 395
T+ L + LL+P +K+D R+ T
Sbjct: 137 -PCKETQIPLKLDTQGLLQPEKPIVLKVDSRDGT 169
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 85.0 bits (201), Expect = 4e-16
Identities = 49/154 (31%), Positives = 84/154 (54%), Gaps = 9/154 (5%)
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHP 309
T D + ++ YL+ V+ ETLR++ V + R D+++ IPKGS + I LH P
Sbjct: 4 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDP 63
Query: 310 QWGPDAHQFRPERWFTENLN----VFAPFSMGKRNCIGKVYAMMSMKVLLVHVFRHYKVT 365
++ + +FRPER+ + + ++ PF G RNCIG +A+M+MK+ L+ V +++
Sbjct: 64 KYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 123
Query: 366 GDISNTEHRLGV----LLKPATGHHIKLDKRNKT 395
T+ L + LL+P +K+D R+ T
Sbjct: 124 -PCKETQIPLKLDTQGLLQPEKPIVLKVDSRDGT 156
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 84.6 bits (200), Expect = 5e-16
Identities = 58/206 (28%), Positives = 100/206 (48%), Gaps = 10/206 (4%)
Query: 172 SSLQETISLLDFILDQDKSKQ---FLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSY 228
+S ++ I ++Q+K Q F + I D+F A +T++T L Y L ++ Y
Sbjct: 258 NSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFG-AGTETTSTTLRYGLLLLLKY 316
Query: 229 PEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVPA-IARKTDIDLKL 287
PEV K+ +EI VG N+ + Y +AV+ E R ++P + D+K
Sbjct: 317 PEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKF 376
Query: 288 KNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFAPFSMGKRNCI 342
KNY IPKG +I L ++ + + P+ F P + ++ N F PFS GKR C+
Sbjct: 377 KNYLIPKGMTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
Query: 343 GKVYAMMSMKVLLVHVFRHYKVTGDI 368
G+ A M + + L + +++ + +
Sbjct: 437 GEGLARMELFLFLTTILQNFNLKSQV 462
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 84.2 bits (199), Expect = 7e-16
Identities = 53/205 (25%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 166 LINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVV 225
+ N L++ +Q ++ + D+ + L+D I I A +T+ + + + L +
Sbjct: 259 ITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFL 318
Query: 226 GSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDID 284
P+V++K+Y+EI VG ++ T +L+ LEA I+E LR+ V P I K ++D
Sbjct: 319 LHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378
Query: 285 LKLKNYTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERWF----TENLN---VFAPFSMG 337
+ + + KG+ + I L LH + + QF PER+ T+ ++ + PF G
Sbjct: 379 SSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438
Query: 338 KRNCIGKVYAMMSMKVLLVHVFRHY 362
R+CIG++ A + +++ + + +
Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRF 463
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 83.8 bits (198), Expect = 9e-16
Identities = 60/220 (27%), Positives = 107/220 (48%), Gaps = 12/220 (5%)
Query: 160 DHHHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALI 219
+H + +NN + + ++ D KS +F + + D+F +A +T++T L
Sbjct: 250 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKS-EFNIENLVGTVADLF-VAGTETTSTTLR 307
Query: 220 YLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIA 278
Y L ++ +PEV K+ +EI +G ++ + Y +AV+ E R +VP +
Sbjct: 308 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 367
Query: 279 RKTDIDLKLKNYTIPKGSSI-GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFA 332
D K +NY IPKG++I ++ LH ++ P+ + F P + +N N F
Sbjct: 368 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFM 426
Query: 333 PFSMGKRNCIGKVYAMMSMKVLLVHVFRHY--KVTGDISN 370
PFS GKR C G+ A M + + L + +++ K D+ N
Sbjct: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 466
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 83.8 bits (198), Expect = 9e-16
Identities = 47/184 (25%), Positives = 97/184 (52%), Gaps = 7/184 (3%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F + +++F A +T +T L Y ++ +PEV+ K+++EI +G
Sbjct: 279 EKNPNTEFYLKNLVMTTLNLFF-AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGK 337
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y EAVI E R ++P +A + + D K +++ +PKG+ + MLG+
Sbjct: 338 NRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGS 397
Query: 305 LHQHPQWGPDAHQFRPERWFTE-----NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHVF 359
+ P++ + P+ + E + F PFS+GKR C G+ A M + + +
Sbjct: 398 ELRDPRFFSNPQDCSPQHFLDEKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIM 457
Query: 360 RHYK 363
++++
Sbjct: 458 QNFR 461
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 83.8 bits (198), Expect = 9e-16
Identities = 60/220 (27%), Positives = 107/220 (48%), Gaps = 12/220 (5%)
Query: 160 DHHHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALI 219
+H + +NN + + ++ D KS +F + + D+F +A +T++T L
Sbjct: 222 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKS-EFNIENLVGTVADLF-VAGTETTSTTLR 279
Query: 220 YLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIA 278
Y L ++ +PEV K+ +EI +G ++ + Y +AV+ E R +VP +
Sbjct: 280 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 339
Query: 279 RKTDIDLKLKNYTIPKGSSI-GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFA 332
D K +NY IPKG++I ++ LH ++ P+ + F P + +N N F
Sbjct: 340 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFM 398
Query: 333 PFSMGKRNCIGKVYAMMSMKVLLVHVFRHY--KVTGDISN 370
PFS GKR C G+ A M + + L + +++ K D+ N
Sbjct: 399 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 438
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 83.8 bits (198), Expect = 9e-16
Identities = 60/220 (27%), Positives = 107/220 (48%), Gaps = 12/220 (5%)
Query: 160 DHHHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALI 219
+H + +NN + + ++ D KS +F + + D+F +A +T++T L
Sbjct: 250 EHQASLDVNNPRDFMDCFLIKMEQEKDNQKS-EFNIENLVGTVADLF-VAGTETTSTTLR 307
Query: 220 YLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIA 278
Y L ++ +PEV K+ +EI +G ++ + Y +AV+ E R +VP +
Sbjct: 308 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 367
Query: 279 RKTDIDLKLKNYTIPKGSSI-GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFA 332
D K +NY IPKG++I ++ LH ++ P+ + F P + +N N F
Sbjct: 368 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFM 426
Query: 333 PFSMGKRNCIGKVYAMMSMKVLLVHVFRHY--KVTGDISN 370
PFS GKR C G+ A M + + L + +++ K D+ N
Sbjct: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 466
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 83.8 bits (198), Expect = 9e-16
Identities = 60/220 (27%), Positives = 107/220 (48%), Gaps = 12/220 (5%)
Query: 160 DHHHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALI 219
+H + +NN + + ++ D KS +F + + D+F +A +T++T L
Sbjct: 250 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKS-EFNIENLVGTVADLF-VAGTETTSTTLR 307
Query: 220 YLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIA 278
Y L ++ +PEV K+ +EI +G ++ + Y +AV+ E R +VP +
Sbjct: 308 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 367
Query: 279 RKTDIDLKLKNYTIPKGSSI-GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFA 332
D K +NY IPKG++I ++ LH ++ P+ + F P + +N N F
Sbjct: 368 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFM 426
Query: 333 PFSMGKRNCIGKVYAMMSMKVLLVHVFRHY--KVTGDISN 370
PFS GKR C G+ A M + + L + +++ K D+ N
Sbjct: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 466
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 83.8 bits (198), Expect = 9e-16
Identities = 60/220 (27%), Positives = 107/220 (48%), Gaps = 12/220 (5%)
Query: 160 DHHHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALI 219
+H + +NN + + ++ D KS +F + + D+F +A +T++T L
Sbjct: 250 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKS-EFNIENLVGTVADLF-VAGTETTSTTLR 307
Query: 220 YLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIA 278
Y L ++ +PEV K+ +EI +G ++ + Y +AV+ E R +VP +
Sbjct: 308 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 367
Query: 279 RKTDIDLKLKNYTIPKGSSI-GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFA 332
D K +NY IPKG++I ++ LH ++ P+ + F P + +N N F
Sbjct: 368 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFM 426
Query: 333 PFSMGKRNCIGKVYAMMSMKVLLVHVFRHY--KVTGDISN 370
PFS GKR C G+ A M + + L + +++ K D+ N
Sbjct: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 466
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 83.8 bits (198), Expect = 9e-16
Identities = 60/220 (27%), Positives = 107/220 (48%), Gaps = 12/220 (5%)
Query: 160 DHHHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALI 219
+H + +NN + + ++ D KS +F + + D+F +A +T++T L
Sbjct: 250 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKS-EFNIENLVGTVADLF-VAGTETTSTTLR 307
Query: 220 YLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIA 278
Y L ++ +PEV K+ +EI +G ++ + Y +AV+ E R +VP +
Sbjct: 308 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 367
Query: 279 RKTDIDLKLKNYTIPKGSSI-GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFA 332
D K +NY IPKG++I ++ LH ++ P+ + F P + +N N F
Sbjct: 368 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFM 426
Query: 333 PFSMGKRNCIGKVYAMMSMKVLLVHVFRHY--KVTGDISN 370
PFS GKR C G+ A M + + L + +++ K D+ N
Sbjct: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 466
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 83.4 bits (197), Expect = 1e-15
Identities = 51/175 (29%), Positives = 90/175 (51%), Gaps = 10/175 (5%)
Query: 197 EEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI-----LAEVGDNKDVTK 251
+ +++ L +T+A+A L+T +G YP V QK+ +E+ L + + +
Sbjct: 219 QALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDM 278
Query: 252 DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQW 311
++L +L Y+ VIKETLR+ VP R +L Y IPKG ++ + H +
Sbjct: 279 EILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEI 338
Query: 312 GPDAHQFRPERWF---TENLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
+ +F P+R+ E+ + F+ PF G R+C+GK +A + +K+ V + RH
Sbjct: 339 FTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 393
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 83.4 bits (197), Expect = 1e-15
Identities = 51/175 (29%), Positives = 90/175 (51%), Gaps = 10/175 (5%)
Query: 197 EEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI-----LAEVGDNKDVTK 251
+ +++ L +T+A+A L+T +G YP V QK+ +E+ L + + +
Sbjct: 288 QALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDM 347
Query: 252 DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQW 311
++L +L Y+ VIKETLR+ VP R +L Y IPKG ++ + H +
Sbjct: 348 EILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEI 407
Query: 312 GPDAHQFRPERWF---TENLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
+ +F P+R+ E+ + F+ PF G R+C+GK +A + +K+ V + RH
Sbjct: 408 FTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 83.4 bits (197), Expect = 1e-15
Identities = 51/175 (29%), Positives = 90/175 (51%), Gaps = 10/175 (5%)
Query: 197 EEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEI-----LAEVGDNKDVTK 251
+ +++ L +T+A+A L+T +G YP V QK+ +E+ L + + +
Sbjct: 288 QALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDM 347
Query: 252 DVLPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQW 311
++L +L Y+ VIKETLR+ VP R +L Y IPKG ++ + H +
Sbjct: 348 EILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEI 407
Query: 312 GPDAHQFRPERWF---TENLNVFA--PFSMGKRNCIGKVYAMMSMKVLLVHVFRH 361
+ +F P+R+ E+ + F+ PF G R+C+GK +A + +K+ V + RH
Sbjct: 408 FTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 83.0 bits (196), Expect = 2e-15
Identities = 60/220 (27%), Positives = 107/220 (48%), Gaps = 12/220 (5%)
Query: 160 DHHHPILINNLESSLQETISLLDFILDQDKSKQFLTDEEIREQIDIFLIASFDTSATALI 219
+H + +NN + + ++ D KS +F + + D+F +A +T++T L
Sbjct: 240 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKS-EFNIENLVGTVADLF-VAGTETTSTTLR 297
Query: 220 YLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIKETLRMYSVVP-AIA 278
Y L ++ +PEV K+ +EI +G ++ + Y +AV+ E R +VP +
Sbjct: 298 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 357
Query: 279 RKTDIDLKLKNYTIPKGSSI-GIMLGTLHQHPQWGPDAHQFRPERWFTENLN-----VFA 332
D K +NY IPKG++I ++ LH ++ P+ + F P + +N N F
Sbjct: 358 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGLFLDKNGNFKKSDYFM 416
Query: 333 PFSMGKRNCIGKVYAMMSMKVLLVHVFRHY--KVTGDISN 370
PFS GKR C G+ A M + + L + +++ K D+ N
Sbjct: 417 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 456
>K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein.
Length = 331
Score = 82.6 bits (195), Expect = 2e-15
Identities = 49/186 (26%), Positives = 99/186 (53%), Gaps = 9/186 (4%)
Query: 186 DQDKSKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGD 245
+++ + +F ++ + +++F I +T +T L Y ++ +P V+ K+++EI +G
Sbjct: 116 EKNPNTEFYLEKLVMTSLNLF-IGGTETVSTTLRYGFLLLIKHPGVEAKVHEEIDRVIGK 174
Query: 246 NKDVTKDVLPKLVYLEAVIKETLRMYSVVPAI-ARKTDIDLKLKNYTIPKGSSIGIMLGT 304
N+ + K+ Y+EA+I E R V+P I + D K +++ +PKG+ + MLG+
Sbjct: 175 NRQPKFEDRAKMPYMEAMIHEIQRFGDVIPMIWPGRVKKDTKFRDFFLPKGTEVYPMLGS 234
Query: 305 LHQHPQWGPDAHQFRPERWFTE------NLNVFAPFSMGKRNCIGKVYAMMSMKVLLVHV 358
+ + P + F P+ FTE + F PFS+G+ NC G+ A M + + V
Sbjct: 235 VLRDPIFLSKPQDFNPQH-FTELEGAPKKSDAFVPFSIGQPNCFGEGLARMELFLFFTTV 293
Query: 359 FRHYKV 364
+++++
Sbjct: 294 MQNFRL 299
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 82.2 bits (194), Expect = 3e-15
Identities = 51/168 (30%), Positives = 78/168 (46%), Gaps = 4/168 (2%)
Query: 194 LTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDV 253
L+ + I+ S D + L+ L + P VQQ + E LA + +
Sbjct: 89 LSPDAIKANCMELTAGSVDRTVFPLLMTLFELARNPNVQQPLRQESLAPAASISEHPQKA 148
Query: 254 LPKLVYLEAVIKETLRMYSVVPAIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQHPQWGP 313
+L L A +KETLR+Y V + R DL L+NY IP G+ + + L +L ++P P
Sbjct: 149 TTELPLLRAALKETLRLYPVGLILERVVSSDLVLQNYHIPAGTLVRVFLYSLGRNPALFP 208
Query: 314 DAHQFRPERWFT---ENLNVF-APFSMGKRNCIGKVYAMMSMKVLLVH 357
++ P+RW N + PF G R C+G+ A M +LL H
Sbjct: 209 RPERYNPQRWLDIKGSGRNFYHVPFGFGMRQCLGRRLAEADMLLLLQH 256
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 81.4 bits (192), Expect = 5e-15
Identities = 56/175 (32%), Positives = 84/175 (48%), Gaps = 9/175 (5%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
S + E+I ++ A FDT TA+ + L + + PE+Q+KI E+ +G +
Sbjct: 298 SGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRP 357
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
P+L YLEA I ET R S +P I T D L + IPK + + ++
Sbjct: 358 RLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHD 417
Query: 309 PQWGPDAHQFRPERWFT-ENLNVFAP-------FSMGKRNCIGKVYAMMSMKVLL 355
P+ D +FRPER+ T + + P F MGKR CIG+V A + + L
Sbjct: 418 PELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFL 472
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 81.4 bits (192), Expect = 5e-15
Identities = 42/140 (30%), Positives = 78/140 (55%), Gaps = 4/140 (2%)
Query: 206 FLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDVTKDVLPKLVYLEAVIK 265
F+ DT+A+ + ++L + ++P+ Q++ +EI +GD +T + L ++ Y IK
Sbjct: 2 FMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIK 61
Query: 266 ETLRMYSVVPAIARKTDIDLKLKN-YTIPKGSSIGIMLGTLHQHPQWGPDAHQFRPERW- 323
E LR+Y VP I+R+ + + ++PKG ++ + + LH +P+ P+ F P R+
Sbjct: 62 EALRLYPPVPGISRELSTPVTFPDGRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSRFA 121
Query: 324 --FTENLNVFAPFSMGKRNC 341
++ + F PFS G RNC
Sbjct: 122 PGSAQHSHAFLPFSGGSRNC 141
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 81.4 bits (192), Expect = 5e-15
Identities = 56/175 (32%), Positives = 84/175 (48%), Gaps = 9/175 (5%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
S + E+I ++ A FDT TA+ + L + + PE+Q+KI E+ +G +
Sbjct: 298 SGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRP 357
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
P+L YLEA I ET R S +P I T D L + IPK + + ++
Sbjct: 358 RLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHD 417
Query: 309 PQWGPDAHQFRPERWFT-ENLNVFAP-------FSMGKRNCIGKVYAMMSMKVLL 355
P+ D +FRPER+ T + + P F MGKR CIG+V A + + L
Sbjct: 418 PELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFL 472
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 81.4 bits (192), Expect = 5e-15
Identities = 56/175 (32%), Positives = 84/175 (48%), Gaps = 9/175 (5%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
S + E+I ++ A FDT TA+ + L + + PE+Q+KI E+ +G +
Sbjct: 298 SGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRP 357
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
P+L YLEA I ET R S +P I T D L + IPK + + ++
Sbjct: 358 RLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHD 417
Query: 309 PQWGPDAHQFRPERWFT-ENLNVFAP-------FSMGKRNCIGKVYAMMSMKVLL 355
P+ D +FRPER+ T + + P F MGKR CIG+V A + + L
Sbjct: 418 PELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFL 472
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 81.4 bits (192), Expect = 5e-15
Identities = 56/175 (32%), Positives = 84/175 (48%), Gaps = 9/175 (5%)
Query: 190 SKQFLTDEEIREQIDIFLIASFDTSATALIYLLTVVGSYPEVQQKIYDEILAEVGDNKDV 249
S + E+I ++ A FDT TA+ + L + + PE+Q+KI E+ +G +
Sbjct: 298 SGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRP 357
Query: 250 TKDVLPKLVYLEAVIKETLRMYSVVP-AIARKTDIDLKLKNYTIPKGSSIGIMLGTLHQH 308
P+L YLEA I ET R S +P I T D L + IPK + + ++
Sbjct: 358 RLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHD 417
Query: 309 PQWGPDAHQFRPERWFT-ENLNVFAP-------FSMGKRNCIGKVYAMMSMKVLL 355
P+ D +FRPER+ T + + P F MGKR CIG+V A + + L
Sbjct: 418 PELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFL 472
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.140 0.424
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 57,375,410
Number of Sequences: 224733
Number of extensions: 2429769
Number of successful extensions: 8982
Number of sequences better than 10.0: 447
Number of HSP's better than 10.0 without gapping: 394
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 7748
Number of HSP's gapped (non-prelim): 586
length of query: 395
length of database: 73,234,838
effective HSP length: 91
effective length of query: 304
effective length of database: 52,784,135
effective search space: 16046377040
effective search space used: 16046377040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 66 (30.7 bits)
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