Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000031-TA|BGIBMGA000031-PA|IPR000873|AMP-dependent
synthetase and ligase, IPR006163|Phosphopantetheine-binding,
IPR002226|Catalase, IPR009081|Acyl carrier protein-like
(783 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q402E3 Cluster: Ebony; n=4; Neoptera|Rep: Ebony - Papil... 1204 0.0
UniRef50_O76858 Cluster: Ebony protein; n=18; Diptera|Rep: Ebony... 767 0.0
UniRef50_UPI0000DB6BFA Cluster: PREDICTED: similar to ebony CG33... 684 0.0
UniRef50_Q9GSP4 Cluster: Mutant e4 ebony; n=2; Drosophila|Rep: M... 504 e-141
UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2; Bac... 286 2e-75
UniRef50_Q0SKF6 Cluster: Non-ribosomal peptide synthetase; n=2; ... 248 3e-64
UniRef50_Q8VQF9 Cluster: Peptide synthetase XpsA; n=1; Xenorhabd... 245 3e-63
UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3; ... 238 5e-61
UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3; ... 235 4e-60
UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide syntheta... 233 1e-59
UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - No... 233 2e-59
UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2; cel... 232 2e-59
UniRef50_Q0S3K6 Cluster: Non-ribosomal peptide synthetase; n=2; ... 232 2e-59
UniRef50_Q87WM8 Cluster: Non-ribosomal peptide synthetase, initi... 231 7e-59
UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|... 231 7e-59
UniRef50_Q0SKF9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 231 7e-59
UniRef50_Q2N3S9 Cluster: Hybrid nonribosomal peptide synthetase/... 230 9e-59
UniRef50_Q4C3C2 Cluster: Amino acid adenylation; n=1; Crocosphae... 229 2e-58
UniRef50_Q0S7I5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 229 2e-58
UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide syntheta... 229 3e-58
UniRef50_A0UUS4 Cluster: Amino acid adenylation domain; n=1; Clo... 229 3e-58
UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide syntheta... 227 7e-58
UniRef50_A6ASZ6 Cluster: Enterobactin synthetase component F; n=... 227 9e-58
UniRef50_A3P7D7 Cluster: Syringomycin synthetase; n=37; Burkhold... 227 9e-58
UniRef50_Q7NVV9 Cluster: Synthetase CbsF; n=3; cellular organism... 224 8e-57
UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospi... 224 8e-57
UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia rhizoxi... 223 1e-56
UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1; Alca... 223 2e-56
UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin s... 223 2e-56
UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 221 4e-56
UniRef50_Q5J1Q6 Cluster: NocB; n=1; Nocardia uniformis subsp. ts... 221 4e-56
UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1; My... 221 4e-56
UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7; Pseudomona... 220 1e-55
UniRef50_Q8DTJ5 Cluster: Putative bacitracin synthetase 1; BacA;... 219 3e-55
UniRef50_Q87WM7 Cluster: Non-ribosomal peptide synthetase, termi... 219 3e-55
UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4; Bacil... 219 3e-55
UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces... 218 5e-55
UniRef50_Q0S5D8 Cluster: Non-ribosomal peptide synthetase; n=2; ... 218 5e-55
UniRef50_A4C379 Cluster: Non-ribosomal peptide synthetase, termi... 217 9e-55
UniRef50_Q8YTR5 Cluster: Peptide synthetase; n=7; Cyanobacteria|... 217 1e-54
UniRef50_Q7N5R5 Cluster: Similar to antibiotic synthetase; n=1; ... 217 1e-54
UniRef50_A4XWA8 Cluster: Amino acid adenylation domain; n=1; Pse... 217 1e-54
UniRef50_A4KUB7 Cluster: TlmIV; n=3; root|Rep: TlmIV - Streptoal... 217 1e-54
UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular... 216 2e-54
UniRef50_Q4IYK4 Cluster: Non-ribosomal peptide synthase:Amino ac... 216 2e-54
UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2; Com... 215 3e-54
UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Ba... 215 4e-54
UniRef50_UPI000038CB2F Cluster: COG1020: Non-ribosomal peptide s... 215 5e-54
UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide syntheta... 215 5e-54
UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine syn... 215 5e-54
UniRef50_Q39GN5 Cluster: Non-ribosomal peptide synthase; n=16; B... 214 7e-54
UniRef50_Q84DH9 Cluster: Peptide synthase; n=3; Streptomyces|Rep... 214 7e-54
UniRef50_Q5DIP4 Cluster: PvdJ; n=19; root|Rep: PvdJ - Pseudomona... 214 7e-54
UniRef50_Q0MYM1 Cluster: Nonribosomal peptide synthetase; n=2; L... 214 7e-54
UniRef50_P45745 Cluster: Dimodular nonribosomal peptide syntheta... 214 9e-54
UniRef50_Q0S6F2 Cluster: Non-ribosomal peptide synthetase; n=2; ... 213 1e-53
UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular o... 213 2e-53
UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6; B... 213 2e-53
UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase module... 213 2e-53
UniRef50_Q5DIU0 Cluster: PvdI; n=3; cellular organisms|Rep: PvdI... 213 2e-53
UniRef50_Q0LPK1 Cluster: Amino acid adenylation; n=1; Herpetosip... 213 2e-53
UniRef50_Q2AZG3 Cluster: Non-ribosomal peptide synthase:Amino ac... 212 3e-53
UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyke... 212 3e-53
UniRef50_O87314 Cluster: FxbC; n=5; Mycobacterium smegmatis|Rep:... 212 3e-53
UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep... 211 5e-53
UniRef50_Q2SKF9 Cluster: Non-ribosomal peptide synthetase module... 211 6e-53
UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 211 6e-53
UniRef50_A1FGJ0 Cluster: Amino acid adenylation; n=2; cellular o... 211 6e-53
UniRef50_Q8YTS0 Cluster: Microcystin synthetase B; n=3; Nostocac... 210 8e-53
UniRef50_Q5ZTI3 Cluster: Peptide synthetase, non-ribosomal; n=2;... 210 8e-53
UniRef50_Q5IW60 Cluster: Phosphinothricin tripeptide synthetase ... 210 8e-53
UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|... 210 8e-53
UniRef50_Q0B1F6 Cluster: Amino acid adenylation domain; n=2; Bac... 210 1e-52
UniRef50_Q3M1N0 Cluster: Amino acid adenylation; n=2; Bacteria|R... 210 1e-52
UniRef50_A5XI24 Cluster: Non-ribosomal peptide synthase; n=23; B... 210 1e-52
UniRef50_A5EHY7 Cluster: Non ribosomal peptide synthase; n=1; Br... 210 1e-52
UniRef50_Q3WDU5 Cluster: Amino acid adenylation; n=1; Frankia sp... 209 2e-52
UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomona... 209 2e-52
UniRef50_A1TW55 Cluster: Amino acid adenylation domain; n=1; Aci... 209 2e-52
UniRef50_Q9HYR8 Cluster: Probable non-ribosomal peptide syntheta... 208 3e-52
UniRef50_Q47NS0 Cluster: Amino acid adenylation; n=1; Thermobifi... 208 3e-52
UniRef50_Q5DIV7 Cluster: PvdI; n=5; Pseudomonas aeruginosa|Rep: ... 208 3e-52
UniRef50_UPI0000510064 Cluster: COG1020: Non-ribosomal peptide s... 208 4e-52
UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide syntheta... 208 4e-52
UniRef50_A0UVH3 Cluster: Amino acid adenylation domain; n=1; Clo... 208 4e-52
UniRef50_P29698 Cluster: Enterobactin synthetase component F; n=... 208 4e-52
UniRef50_A1FGJ5 Cluster: Amino acid adenylation; n=1; Pseudomona... 208 6e-52
UniRef50_UPI00004DBA5D Cluster: UPI00004DBA5D related cluster; n... 206 1e-51
UniRef50_Q2SGN2 Cluster: Non-ribosomal peptide synthetase module... 206 1e-51
UniRef50_Q0S1Z9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 206 1e-51
UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino ac... 206 2e-51
UniRef50_Q8GGQ3 Cluster: Nonribosomal peptide synthetase; n=2; S... 206 2e-51
UniRef50_Q0S6F3 Cluster: Non-ribosomal peptide synthetase; n=2; ... 206 2e-51
UniRef50_Q44103 Cluster: Peptide-synthetase; n=1; Amycolatopsis ... 205 3e-51
UniRef50_Q0LP44 Cluster: Amino acid adenylation; n=1; Herpetosip... 205 3e-51
UniRef50_Q3JQV3 Cluster: Nonribosomal peptide synthetase; n=24; ... 204 5e-51
UniRef50_Q9F9L4 Cluster: Micrococcin P1 peptide synthetase; n=1;... 204 5e-51
UniRef50_Q1RS70 Cluster: Hybrid NRPS/PKS; n=4; cellular organism... 204 7e-51
UniRef50_A1TTJ0 Cluster: Amino acid adenylation domain; n=1; Aci... 204 7e-51
UniRef50_UPI00005F935B Cluster: COG1020: Non-ribosomal peptide s... 204 9e-51
UniRef50_Q847C8 Cluster: NdaB; n=32; Cyanobacteria|Rep: NdaB - N... 204 9e-51
UniRef50_A5IDB4 Cluster: Peptide synthetase; n=4; Legionella pne... 204 9e-51
UniRef50_A1B557 Cluster: Amino acid adenylation domain; n=2; Pro... 203 1e-50
UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C ... 203 2e-50
UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3; Strept... 202 3e-50
UniRef50_Q8G982 Cluster: Peptide synthetase; n=102; Cyanobacteri... 202 3e-50
UniRef50_Q2XNF8 Cluster: Nonribosomal peptide synthetase-polyket... 202 4e-50
UniRef50_A4F9A3 Cluster: Putative non-ribosomal peptide syntheta... 202 4e-50
UniRef50_Q094I7 Cluster: Aminotransferase, class III family; n=9... 201 5e-50
UniRef50_Q4U445 Cluster: DszC; n=3; Proteobacteria|Rep: DszC - P... 201 7e-50
UniRef50_Q0SE34 Cluster: Non-ribosomal peptide synthetase; n=1; ... 201 7e-50
UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1; ... 200 9e-50
UniRef50_Q8G983 Cluster: Peptide synthetase; n=118; cellular org... 200 9e-50
UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5; ... 200 9e-50
UniRef50_Q0X0B9 Cluster: Putative non-ribosomal peptide syntheta... 200 9e-50
UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2; Bac... 200 1e-49
UniRef50_A4BRH4 Cluster: Probable peptide synthetase protein; n=... 200 1e-49
UniRef50_A0YGI5 Cluster: Peptide synthetase; n=1; marine gamma p... 200 1e-49
UniRef50_Q9RK14 Cluster: Putative peptide synthetase; n=1; Strep... 200 2e-49
UniRef50_Q8YWG6 Cluster: Peptide synthetase; n=3; Nostocaceae|Re... 200 2e-49
UniRef50_A4PHM3 Cluster: Hybrid non ribosomal peptide synthetase... 200 2e-49
UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1; Clo... 200 2e-49
UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D;... 200 2e-49
UniRef50_Q4CA71 Cluster: Amino acid adenylation; n=1; Crocosphae... 199 2e-49
UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino ac... 199 2e-49
UniRef50_Q1D3K9 Cluster: Non-ribosomal peptide synthase; n=1; My... 199 2e-49
UniRef50_A6VYF8 Cluster: Amino acid adenylation domain; n=1; Mar... 199 2e-49
UniRef50_Q4JTA1 Cluster: Non-ribosomal peptide synthetase; n=1; ... 199 3e-49
UniRef50_Q643C7 Cluster: Mannopeptimycin peptide synthetase MppA... 199 3e-49
UniRef50_Q0TGF7 Cluster: Probable peptide synthetase protein; n=... 199 3e-49
UniRef50_A0PTU8 Cluster: Non-ribosomal peptide synthetase MbtE; ... 199 3e-49
UniRef50_Q840C8 Cluster: Catechol siderophore synthase DhbF-like... 198 4e-49
UniRef50_A5EHY6 Cluster: Non-ribosomal peptide synthase; n=2; ce... 198 5e-49
UniRef50_A3KI35 Cluster: Putative peptide synthetase; n=1; Strep... 198 5e-49
UniRef50_Q5YVZ9 Cluster: Putative non-ribosomal peptide syntheta... 198 6e-49
UniRef50_Q3M5N4 Cluster: Amino acid adenylation; n=1; Anabaena v... 198 6e-49
UniRef50_Q6WZB2 Cluster: Nonribosomal peptide synthetase; n=1; S... 198 6e-49
UniRef50_Q3WHQ1 Cluster: Non-ribosomal peptide synthase:Amino ac... 198 6e-49
UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2; Cyanobacte... 197 8e-49
UniRef50_Q1DBW4 Cluster: Non-ribosomal peptide synthetase; n=3; ... 197 8e-49
UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2; Bac... 197 8e-49
UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1; S... 197 8e-49
UniRef50_UPI000045BBC7 Cluster: COG1020: Non-ribosomal peptide s... 197 1e-48
UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC 71... 197 1e-48
UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|... 197 1e-48
UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1; Strepto... 196 1e-48
UniRef50_Q4ZV21 Cluster: Non-ribosomal peptide synthase:Amino ac... 196 2e-48
UniRef50_Q216S9 Cluster: Amino acid adenylation; n=1; Rhodopseud... 196 2e-48
UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces... 196 2e-48
UniRef50_Q08MM0 Cluster: Linear gramicidin synthetase subunit B;... 196 2e-48
UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide syntheta... 196 2e-48
UniRef50_A3KFG6 Cluster: PstD protein; n=1; Actinoplanes friulie... 196 2e-48
UniRef50_Q0SEB1 Cluster: Non-ribosomal peptide synthetase; n=2; ... 195 3e-48
UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7; ... 195 3e-48
UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep... 195 3e-48
UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabd... 195 4e-48
UniRef50_Q0SEL9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 194 6e-48
UniRef50_A7IZW1 Cluster: OciA; n=1; Planktothrix agardhii NIVA-C... 194 6e-48
UniRef50_Q88F79 Cluster: Non-ribosomal siderophore peptide synth... 194 8e-48
UniRef50_Q5JCL8 Cluster: Putative non-ribosomal peptide syntheta... 194 8e-48
UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2; ... 194 8e-48
UniRef50_Q0LP45 Cluster: Amino acid adenylation; n=1; Herpetosip... 194 1e-47
UniRef50_Q8YTR4 Cluster: All2649 protein; n=3; Nostocaceae|Rep: ... 193 1e-47
UniRef50_Q0LN53 Cluster: Amino acid adenylation; n=1; Herpetosip... 193 1e-47
UniRef50_A3INW8 Cluster: Peptide synthetase; n=3; Chroococcales|... 193 1e-47
UniRef50_A0ZF79 Cluster: Non-ribosomal peptide synthase; n=6; Cy... 193 1e-47
UniRef50_Q9AMR5 Cluster: ID930; n=1; Bradyrhizobium japonicum|Re... 193 2e-47
UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:... 193 2e-47
UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;... 193 2e-47
UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;... 193 2e-47
UniRef50_Q1ER08 Cluster: Cereulide synthetase 1; n=6; Bacillus|R... 193 2e-47
UniRef50_Q0RI59 Cluster: Non-ribosomal peptide synthetase; n=3; ... 193 2e-47
UniRef50_A0V6U0 Cluster: Amino acid adenylation domain; n=1; Del... 193 2e-47
UniRef50_A1FGJ4 Cluster: Amino acid adenylation; n=1; Pseudomona... 192 2e-47
UniRef50_Q81DB7 Cluster: Peptide synthetase; n=4; Bacillus cereu... 192 4e-47
UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide sy... 192 4e-47
UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1; Burk... 192 4e-47
UniRef50_Q70JX4 Cluster: FenD protein; n=18; Bacillus|Rep: FenD ... 192 4e-47
UniRef50_Q0VZ70 Cluster: Non ribosomal peptide synthase; n=1; Ch... 192 4e-47
UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, termi... 191 5e-47
UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1; Strept... 191 5e-47
UniRef50_Q70C52 Cluster: Non-ribosomal peptide synthase; n=1; Xa... 191 5e-47
UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep... 191 5e-47
UniRef50_A0UVJ0 Cluster: Amino acid adenylation domain; n=2; Clo... 191 5e-47
UniRef50_Q0RMQ5 Cluster: Putative non-ribosomal peptide syntheta... 191 7e-47
UniRef50_P39845 Cluster: Peptide synthetase 1; n=8; Bacillus|Rep... 191 7e-47
UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Ph... 190 9e-47
UniRef50_Q5Z1T0 Cluster: Putative non-ribosomal peptide syntheta... 190 9e-47
UniRef50_Q9F5J4 Cluster: SimH; n=5; Streptomyces|Rep: SimH - Str... 190 9e-47
UniRef50_A0PRJ7 Cluster: Peptide synthetase Nrp; n=1; Mycobacter... 190 9e-47
UniRef50_A0ACQ7 Cluster: Putative peptide synthetase; n=1; Strep... 190 9e-47
UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 190 1e-46
UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3; Bac... 190 1e-46
UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 190 1e-46
UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes... 190 1e-46
UniRef50_Q45R85 Cluster: Peptide synthetase; n=2; Actinomycetale... 190 2e-46
UniRef50_Q2ANX0 Cluster: Non-ribosomal peptide synthase:Amino ac... 190 2e-46
UniRef50_UPI000045BE69 Cluster: COG1020: Non-ribosomal peptide s... 189 2e-46
UniRef50_Q7N7D0 Cluster: Complete genome; segment 5/17; n=1; Pho... 189 2e-46
UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1; Myxoc... 189 2e-46
UniRef50_A7IJ33 Cluster: Amino acid adenylation domain; n=1; Xan... 189 2e-46
UniRef50_A6VVR6 Cluster: Amino acid adenylation domain; n=1; Mar... 189 2e-46
UniRef50_A4ZPY5 Cluster: DepE; n=2; cellular organisms|Rep: DepE... 189 2e-46
UniRef50_Q9I157 Cluster: PvdL; n=23; root|Rep: PvdL - Pseudomona... 189 3e-46
UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibio... 189 3e-46
UniRef50_Q6N4J8 Cluster: Possible McyE polykeitde synthase and p... 189 3e-46
UniRef50_Q5J1Q7 Cluster: NocA; n=1; Nocardia uniformis subsp. ts... 189 3e-46
UniRef50_A6YEH2 Cluster: CmnA; n=1; Saccharothrix mutabilis subs... 189 3e-46
UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine syn... 189 3e-46
UniRef50_Q2SHZ1 Cluster: Non-ribosomal peptide synthetase module... 188 4e-46
UniRef50_Q7BQ70 Cluster: Putative peptide synthetase/polyketide ... 188 4e-46
UniRef50_Q70C47 Cluster: Polyketide non-ribosomal peptide syntha... 188 4e-46
UniRef50_A5W126 Cluster: Amino acid adenylation domain; n=2; Pse... 188 4e-46
UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5; roo... 188 4e-46
UniRef50_Q93H59 Cluster: Non-ribosimal peptide synthetase; n=1; ... 188 5e-46
UniRef50_Q47NS1 Cluster: Amino acid adenylation; n=1; Thermobifi... 188 5e-46
UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria... 188 5e-46
UniRef50_Q0LKI6 Cluster: Amino acid adenylation; n=1; Herpetosip... 188 5e-46
UniRef50_Q08N46 Cluster: Condensation domain protein; n=3; Stigm... 188 5e-46
UniRef50_A6EWZ1 Cluster: Peptide synthetase; n=1; Marinobacter a... 188 5e-46
UniRef50_A0ZL90 Cluster: Non-ribosomal peptide synthase; n=1; No... 188 5e-46
UniRef50_Q9FB18 Cluster: Peptide synthetase NRPS2-1; n=1; Strept... 188 7e-46
UniRef50_A7BXM0 Cluster: Non-ribosomal peptide synthetase; n=2; ... 188 7e-46
UniRef50_Q0LIS9 Cluster: Amino acid adenylation; n=1; Herpetosip... 187 9e-46
UniRef50_Q9Z5F4 Cluster: Ta1; n=4; Bacteria|Rep: Ta1 - Myxococcu... 187 1e-45
UniRef50_Q0K0K6 Cluster: Non-ribosomal peptide synthetase module... 187 1e-45
UniRef50_A5FI40 Cluster: Amino acid adenylation domain; n=1; Fla... 187 1e-45
UniRef50_A3YGJ0 Cluster: Amino acid adenylation; n=1; Marinomona... 187 1e-45
UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9;... 187 1e-45
UniRef50_Q1IA18 Cluster: Putative non-ribosomal peptide syntheta... 186 2e-45
UniRef50_A4KVL5 Cluster: Non-ribosomal peptide synthetase module... 186 2e-45
UniRef50_Q0LP29 Cluster: Amino acid adenylation; n=1; Herpetosip... 186 3e-45
UniRef50_Q89T13 Cluster: Bll2237 protein; n=2; Bradyrhizobium|Re... 185 4e-45
UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep: ... 185 4e-45
UniRef50_Q847C7 Cluster: NdaA; n=5; cellular organisms|Rep: NdaA... 185 4e-45
UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1; ... 185 4e-45
UniRef50_Q7D791 Cluster: Peptide synthetase; n=18; Mycobacterium... 185 5e-45
UniRef50_Q2XNF7 Cluster: L-alanine specific nonribosomal peptide... 185 5e-45
UniRef50_Q1D6A1 Cluster: Non-ribosomal peptide synthase/polyketi... 185 5e-45
UniRef50_Q1D4E9 Cluster: Non-ribosomal peptide synthase/polyketi... 185 5e-45
UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria... 185 5e-45
UniRef50_Q8CUZ9 Cluster: Monomodular nonribosomal peptide synthe... 184 6e-45
UniRef50_Q311J1 Cluster: Amino acid adenylation; n=9; Bacteria|R... 184 6e-45
UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular orga... 184 6e-45
UniRef50_Q0LLT6 Cluster: Amino acid adenylation; n=1; Herpetosip... 184 6e-45
UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-C... 184 6e-45
UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3; Pseudomona... 184 8e-45
UniRef50_A4XD41 Cluster: Amino acid adenylation domain precursor... 184 8e-45
UniRef50_UPI000038CDA7 Cluster: COG1020: Non-ribosomal peptide s... 184 1e-44
UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2; My... 184 1e-44
UniRef50_A6UN00 Cluster: Amino acid adenylation domain; n=1; Sin... 184 1e-44
UniRef50_A1ZSC1 Cluster: Mixed type I polyketide synthase-peptid... 184 1e-44
UniRef50_A0JZK7 Cluster: Amino acid adenylation domain; n=1; Art... 184 1e-44
UniRef50_Q4C9F4 Cluster: Non-ribosomal peptide synthase:Amino ac... 183 1e-44
UniRef50_Q0VNL6 Cluster: Non-ribosomal peptide synthase; n=1; Al... 183 1e-44
UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosip... 183 1e-44
UniRef50_A4FE18 Cluster: Non-ribosomal peptide synthetase; n=3; ... 183 1e-44
UniRef50_A1G2R8 Cluster: Amino acid adenylation domain; n=1; Sal... 183 1e-44
UniRef50_Q62C03 Cluster: Nonribosomal peptide synthetase DhbF; n... 183 2e-44
UniRef50_Q09D72 Cluster: Linear gramicidin synthetase subunit D;... 182 2e-44
UniRef50_A1G2S8 Cluster: Amino acid adenylation domain; n=1; Sal... 182 2e-44
UniRef50_A0V6U3 Cluster: Amino acid adenylation domain; n=1; Del... 182 2e-44
UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino ac... 182 3e-44
UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for vi... 182 3e-44
UniRef50_Q643C6 Cluster: Mannopeptimycin peptide synthetase MppB... 182 4e-44
UniRef50_Q0LP42 Cluster: Amino acid adenylation; n=1; Herpetosip... 182 4e-44
UniRef50_A6UN01 Cluster: Amino acid adenylation domain; n=1; Sin... 182 4e-44
UniRef50_A4JPB0 Cluster: Amino acid adenylation domain; n=1; Bur... 182 4e-44
UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2; Chroococca... 182 4e-44
UniRef50_Q0VZ71 Cluster: Non ribosomal peptide synthase; n=1; Ch... 181 6e-44
UniRef50_Q0LLQ8 Cluster: Amino acid adenylation; n=2; Herpetosip... 181 6e-44
UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Fir... 181 6e-44
UniRef50_O68006 Cluster: Bacitracin synthetase 1 (BA1) [Includes... 181 6e-44
UniRef50_Q8GGP3 Cluster: Hybrid nonribosomal peptide synthetase ... 181 8e-44
UniRef50_Q1D3L3 Cluster: Non-ribosomal peptide synthase; n=1; My... 181 8e-44
UniRef50_Q216S7 Cluster: Amino acid adenylation; n=1; Rhodopseud... 180 1e-43
UniRef50_Q09E86 Cluster: AMP-binding enzyme domain protein; n=1;... 180 1e-43
UniRef50_Q2SHY7 Cluster: Polyketide synthase modules and related... 180 1e-43
UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino ac... 180 2e-43
UniRef50_Q2AZ45 Cluster: Amino acid adenylation; n=2; Bacillus c... 180 2e-43
UniRef50_A2C8M5 Cluster: Putative uncharacterized protein; n=1; ... 180 2e-43
UniRef50_Q93H69 Cluster: Non-ribosomal peptide synthetase; n=1; ... 179 2e-43
UniRef50_Q9FB27 Cluster: Peptide synthetase NRPS9-8; n=2; Actino... 179 2e-43
UniRef50_Q50JA3 Cluster: Nonribosomal peptide synthetase; n=2; C... 179 2e-43
UniRef50_A1TTI9 Cluster: Amino acid adenylation domain; n=1; Aci... 179 3e-43
UniRef50_Q1D3T0 Cluster: Non-ribosomal peptide synthase MxaA; n=... 178 4e-43
UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacte... 178 4e-43
UniRef50_Q3M3K2 Cluster: Amino acid adenylation; n=2; Nostocacea... 178 5e-43
UniRef50_Q93N87 Cluster: Peptide synthetase; n=12; Bacteria|Rep:... 178 5e-43
UniRef50_Q7BQ71 Cluster: Peptide synthetase-like protein; n=1; B... 178 5e-43
UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: M... 178 5e-43
UniRef50_A4ZPY4 Cluster: DepD; n=3; Chromobacterium violaceum|Re... 178 5e-43
UniRef50_A3P7D5 Cluster: Non-ribosomal peptide synthase; n=21; B... 178 5e-43
UniRef50_Q12HS0 Cluster: Amino acid adenylation; n=1; Shewanella... 177 7e-43
UniRef50_A5FI38 Cluster: Amino acid adenylation domain; n=2; Bac... 177 7e-43
UniRef50_A4F3K7 Cluster: Non-ribosomal peptide synthetase; n=3; ... 177 7e-43
UniRef50_A3IZW4 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 177 7e-43
UniRef50_Q2T5Y9 Cluster: Peptide synthetase, putative; n=10; pse... 177 9e-43
UniRef50_Q0LLQ9 Cluster: Amino acid adenylation; n=1; Herpetosip... 177 9e-43
UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1; Clo... 177 9e-43
UniRef50_Q3M5M7 Cluster: Amino acid adenylation; n=1; Anabaena v... 177 1e-42
UniRef50_A7BKL9 Cluster: Non-ribosomal peptide synthetase; n=2; ... 177 1e-42
UniRef50_Q8YTR9 Cluster: Peptide synthetase; n=2; Nostocaceae|Re... 176 2e-42
UniRef50_Q4ZVI2 Cluster: Amino acid adenylation; n=4; Pseudomona... 176 2e-42
UniRef50_Q2JA64 Cluster: Amino acid adenylation; n=3; Actinomyce... 176 2e-42
UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep: NR... 176 2e-42
UniRef50_A5EJ32 Cluster: Putative non-ribosomal peptide synthase... 176 2e-42
UniRef50_Q70LM7 Cluster: Linear gramicidin synthetase subunit A ... 176 2e-42
UniRef50_Q3JS97 Cluster: Unnamed protein product; n=10; Burkhold... 176 2e-42
UniRef50_Q6E7J5 Cluster: JamO; n=1; Lyngbya majuscula|Rep: JamO ... 176 2e-42
UniRef50_Q7N7D7 Cluster: Similarities with probable non-ribosoma... 175 3e-42
UniRef50_Q2VQ17 Cluster: Nonribosomal peptide synthetase A; n=1;... 175 3e-42
UniRef50_A1G504 Cluster: Amino acid adenylation domain; n=1; Sal... 175 3e-42
UniRef50_A0UXD5 Cluster: Amino acid adenylation domain; n=1; Clo... 175 4e-42
UniRef50_Q9LCU0 Cluster: PstD; n=2; Mycobacterium avium|Rep: Pst... 175 5e-42
UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Re... 175 5e-42
UniRef50_Q4H1C8 Cluster: Non-ribosomal peptide synthetase B; n=1... 175 5e-42
UniRef50_O52803 Cluster: PCZA361.18; n=3; cellular organisms|Rep... 175 5e-42
UniRef50_Q9AKS6 Cluster: Siderophore non-ribosomal peptide synth... 174 7e-42
UniRef50_Q8GN23 Cluster: Peptide synthetase; n=1; Fischerella sp... 174 7e-42
UniRef50_A7BRU4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 174 7e-42
UniRef50_A4KVL6 Cluster: Non-ribosomal peptide synthetase module... 174 7e-42
UniRef50_A1G7W6 Cluster: Amino acid adenylation domain; n=2; Sal... 174 7e-42
UniRef50_Q83DF1 Cluster: Peptide synthetase, putative; n=6; Coxi... 174 9e-42
UniRef50_Q1IBI9 Cluster: Putative non-ribosomal peptide syntheta... 174 9e-42
UniRef50_A1EX07 Cluster: Linear gramicidin synthetase subunit C;... 174 9e-42
UniRef50_A4FCX9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 173 1e-41
UniRef50_A3HJ78 Cluster: Amino acid adenylation domain; n=1; Pse... 173 1e-41
UniRef50_Q2SKG1 Cluster: Non-ribosomal peptide synthetase module... 173 2e-41
UniRef50_Q4CA68 Cluster: Amino acid adenylation; n=1; Crocosphae... 173 2e-41
UniRef50_O69825 Cluster: Putative peptide synthase; n=1; Strepto... 173 2e-41
UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Re... 173 2e-41
UniRef50_A4XD38 Cluster: Amino acid adenylation domain; n=2; Sal... 173 2e-41
UniRef50_Q2UIN6 Cluster: Non-ribosomal peptide synthetase module... 173 2e-41
UniRef50_Q2SHZ4 Cluster: Non-ribosomal peptide synthetase module... 172 3e-41
UniRef50_Q5IW58 Cluster: Phosphinothricin tripeptide synthetase ... 172 3e-41
UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34; B... 172 3e-41
UniRef50_P27206 Cluster: Surfactin synthetase subunit 1; n=15; B... 172 3e-41
UniRef50_Q211M6 Cluster: Amino acid adenylation; n=1; Rhodopseud... 172 4e-41
UniRef50_Q0RMQ3 Cluster: Non-ribosomal peptide synthase; n=1; Fr... 172 4e-41
UniRef50_Q0K0K2 Cluster: Non-ribosomal peptide synthetase; n=1; ... 172 4e-41
UniRef50_A4KUA9 Cluster: TlmIX; n=2; Actinomycetales|Rep: TlmIX ... 172 4e-41
UniRef50_A4BRH6 Cluster: Amino acid adenylation; n=1; Nitrococcu... 172 4e-41
UniRef50_A1G7D3 Cluster: Amino acid adenylation domain; n=3; Act... 172 4e-41
UniRef50_Q8GGR4 Cluster: Nonribosomal peptide synthetase; n=1; S... 171 5e-41
UniRef50_A4C382 Cluster: Amino acid adenylation; n=1; Pseudoalte... 171 5e-41
UniRef50_A0ZF81 Cluster: Amino acid adenylation protein; n=3; Ba... 171 5e-41
UniRef50_Q8PKR8 Cluster: ATP-dependent serine activating enzyme;... 171 6e-41
UniRef50_Q2SGM6 Cluster: Non-ribosomal peptide synthetase module... 171 6e-41
UniRef50_A7T272 Cluster: Predicted protein; n=1; Nematostella ve... 171 6e-41
UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9; Ba... 171 6e-41
UniRef50_A6VYF6 Cluster: Amino acid adenylation domain; n=1; Mar... 171 8e-41
UniRef50_Q2JBJ2 Cluster: Amino acid adenylation; n=1; Frankia sp... 170 1e-40
UniRef50_Q8KSQ1 Cluster: Peptide synthetase ScpsA; n=1; Saccharo... 170 1e-40
UniRef50_Q1D3K7 Cluster: Non-ribosomal peptide synthase; n=1; My... 170 1e-40
UniRef50_Q110E8 Cluster: Amino acid adenylation domain; n=1; Tri... 170 1e-40
UniRef50_A4C386 Cluster: Amino acid adenylation; n=1; Pseudoalte... 170 1e-40
UniRef50_A4C380 Cluster: Putative uncharacterized protein; n=1; ... 170 1e-40
UniRef50_A1G2S7 Cluster: Amino acid adenylation domain; n=1; Sal... 170 1e-40
UniRef50_Q8L334 Cluster: Peptide synthetase; n=14; Nostocaceae|R... 170 1e-40
UniRef50_Q5V8A8 Cluster: LtxA; n=1; Lyngbya majuscula|Rep: LtxA ... 170 1e-40
UniRef50_Q0LN54 Cluster: Amino acid adenylation; n=1; Herpetosip... 170 1e-40
UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacil... 170 1e-40
UniRef50_Q2JYI9 Cluster: Vicibactin biosynthesis non-ribosomal p... 169 2e-40
UniRef50_Q333U8 Cluster: NRPS protein; n=1; Micromonospora sp. M... 169 2e-40
UniRef50_Q0W980 Cluster: Non-ribosomal peptide synthetase; n=2; ... 169 2e-40
UniRef50_Q45R84 Cluster: Peptide synthetase; n=3; Bacteria|Rep: ... 169 2e-40
UniRef50_Q0LN52 Cluster: Amino acid adenylation; n=1; Herpetosip... 169 2e-40
UniRef50_A4XD37 Cluster: Amino acid adenylation domain; n=2; Sal... 169 2e-40
UniRef50_Q0YRE2 Cluster: Amino acid adenylation; n=1; Chlorobium... 169 3e-40
UniRef50_A7DBD7 Cluster: Non-ribosomal peptide synthetase; n=4; ... 169 3e-40
UniRef50_A3INW9 Cluster: Amino acid adenylation; n=1; Cyanothece... 169 3e-40
UniRef50_UPI00005F40EE Cluster: hypothetical protein VchoR_02002... 168 4e-40
UniRef50_Q70P97 Cluster: MelC protein; n=4; Cystobacteraceae|Rep... 168 4e-40
UniRef50_Q8CQA8 Cluster: Surfactin synthetase; n=14; Staphylococ... 168 6e-40
UniRef50_Q63CQ5 Cluster: Multifunctional nonribosomal peptide sy... 168 6e-40
UniRef50_A3INX3 Cluster: Non-ribosomal peptide synthase/polyketi... 168 6e-40
UniRef50_Q8PKR7 Cluster: ATP-dependent serine activating enzyme;... 167 8e-40
UniRef50_Q93GX0 Cluster: Non-ribosomal peptide synthetase; n=2; ... 167 1e-39
UniRef50_Q8YTR8 Cluster: Peptide synthetase; n=2; Nostocaceae|Re... 167 1e-39
UniRef50_Q6VT93 Cluster: Mixed type I polyketide synthase-peptid... 167 1e-39
UniRef50_A1T3T8 Cluster: Amino acid adenylation domain; n=2; cel... 167 1e-39
UniRef50_A1BDX6 Cluster: Amino acid adenylation domain; n=1; Chl... 167 1e-39
UniRef50_Q6RKE1 Cluster: Polyketide synthase; n=1; Cochliobolus ... 167 1e-39
UniRef50_Q9I1H0 Cluster: Probable non-ribosomal peptide syntheta... 167 1e-39
UniRef50_Q0YRD8 Cluster: Amino acid adenylation; n=2; cellular o... 167 1e-39
UniRef50_A4XWA9 Cluster: Amino acid adenylation domain; n=1; Pse... 167 1e-39
UniRef50_A4BRH2 Cluster: Amino acid adenylation; n=1; Nitrococcu... 166 2e-39
UniRef50_Q982I6 Cluster: Peptide synthetase; n=1; Mesorhizobium ... 166 2e-39
UniRef50_Q8XQ64 Cluster: Putative peptide synthetase protein; n=... 166 2e-39
UniRef50_Q63CQ7 Cluster: Multifunctional nonribosomal peptide sy... 166 2e-39
UniRef50_Q8GGS2 Cluster: Nonribosomal peptide synthetase; n=1; S... 166 2e-39
UniRef50_Q6SK65 Cluster: Peptide synthetase; n=5; cellular organ... 166 2e-39
UniRef50_Q0LN68 Cluster: Amino acid adenylation; n=1; Herpetosip... 166 2e-39
UniRef50_Q8GGQ9 Cluster: Nonribosomal peptide synthetase; n=1; S... 165 3e-39
UniRef50_Q333U7 Cluster: NRPS; n=2; Actinomycetales|Rep: NRPS - ... 165 3e-39
UniRef50_Q7N1E3 Cluster: Similar to proteins involved in antibio... 165 4e-39
UniRef50_Q0LNS7 Cluster: Amino acid adenylation; n=1; Herpetosip... 165 4e-39
UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1; M... 165 4e-39
UniRef50_A3KFG5 Cluster: PstC protein; n=2; Actinomycetales|Rep:... 165 4e-39
UniRef50_Q68RS4 Cluster: PrnA; n=1; Prochloron didemni|Rep: PrnA... 165 5e-39
UniRef50_Q3EYR3 Cluster: Peptide synthetase; n=3; Bacillus cereu... 165 5e-39
UniRef50_A7IE17 Cluster: Amino acid adenylation domain; n=1; Xan... 165 5e-39
UniRef50_A4KVK8 Cluster: Probable non-ribosomal peptide syntheta... 165 5e-39
UniRef50_A3HT12 Cluster: Non-ribosomal peptide synthase; n=1; Al... 165 5e-39
UniRef50_A0FXQ3 Cluster: Amino acid adenylation domain; n=2; Bac... 165 5e-39
UniRef50_Q93GZ5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 164 7e-39
UniRef50_Q21E99 Cluster: Amino acid adenylation; n=2; Bacteria|R... 164 7e-39
UniRef50_Q1D3L0 Cluster: Non-ribosomal peptide synthase; n=1; My... 164 7e-39
UniRef50_Q12IB9 Cluster: Amino acid adenylation; n=3; cellular o... 164 7e-39
UniRef50_Q2SHY9 Cluster: Non-ribosomal peptide synthetase module... 163 1e-38
UniRef50_Q3EYD4 Cluster: Peptide synthetase; n=2; Bacillus thuri... 163 1e-38
UniRef50_Q02HM0 Cluster: Putative non-ribosomal peptide syntheta... 163 1e-38
UniRef50_A4FEM4 Cluster: Non-ribosomal peptide synthetase module... 163 1e-38
UniRef50_A3YFF6 Cluster: Amino acid adenylation; n=2; Bacteria|R... 163 1e-38
UniRef50_A0UXC9 Cluster: Amino acid adenylation domain; n=2; Bac... 163 1e-38
UniRef50_A0FCL0 Cluster: MerP; n=2; Streptomyces|Rep: MerP - Str... 163 1e-38
UniRef50_Q6DNE7 Cluster: CurF; n=1; Lyngbya majuscula|Rep: CurF ... 163 2e-38
UniRef50_Q0BVN1 Cluster: Non-ribosomal peptide synthetase module... 163 2e-38
UniRef50_Q98JF4 Cluster: Peptide synthetase; n=1; Mesorhizobium ... 163 2e-38
UniRef50_Q93GZ0 Cluster: Non-ribosomal peptide synthetase; n=1; ... 163 2e-38
UniRef50_Q11F62 Cluster: Amino acid adenylation domain; n=1; Mes... 163 2e-38
UniRef50_A5P2I4 Cluster: Amino acid adenylation domain; n=6; Alp... 163 2e-38
UniRef50_A4C385 Cluster: Amino acid adenylation; n=6; Pseudoalte... 163 2e-38
UniRef50_A3N9V0 Cluster: Linear gramicidin synthetase subunit D;... 163 2e-38
UniRef50_A3DGP4 Cluster: Amino acid adenylation domain; n=1; Clo... 163 2e-38
UniRef50_A1G7D4 Cluster: Amino acid adenylation domain; n=2; Mic... 163 2e-38
UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2; No... 163 2e-38
UniRef50_UPI0000DAE7B3 Cluster: hypothetical protein Rgryl_01001... 162 3e-38
UniRef50_Q9AG79 Cluster: Nonribosomal peptide synthetase 3-2; n=... 162 3e-38
UniRef50_Q939Z1 Cluster: Peptide synthetase; n=7; Actinomycetale... 162 3e-38
UniRef50_Q1D593 Cluster: Non-ribosomal peptide synthetase; n=4; ... 162 3e-38
UniRef50_Q0RMQ8 Cluster: Non-ribosomal peptide synthetase; n=1; ... 162 3e-38
UniRef50_Q0LKI8 Cluster: Amino acid adenylation; n=1; Herpetosip... 162 3e-38
UniRef50_A6V024 Cluster: Amino acid adenylation domain; n=1; Pse... 162 3e-38
UniRef50_A6E8C2 Cluster: Non-ribosomal peptide synthetase/polyke... 162 3e-38
UniRef50_Q183T6 Cluster: D-alanine--poly(Phosphoribitol) ligase ... 162 4e-38
UniRef50_Q0LN70 Cluster: Amino acid adenylation; n=1; Herpetosip... 162 4e-38
UniRef50_Q0LIS7 Cluster: Amino acid adenylation; n=1; Herpetosip... 162 4e-38
UniRef50_Q9FB23 Cluster: Peptide synthetase NRPS5-4-3; n=1; Stre... 161 5e-38
UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphae... 161 5e-38
UniRef50_Q2MFA3 Cluster: Putative nonribosomal peptide synthetas... 161 5e-38
UniRef50_A6VYG2 Cluster: Amino acid adenylation domain; n=1; Mar... 161 5e-38
UniRef50_A6VYF7 Cluster: Amino acid adenylation domain; n=1; Mar... 161 5e-38
UniRef50_A5FI45 Cluster: Amino acid adenylation domain; n=1; Fla... 161 5e-38
UniRef50_A4KUB2 Cluster: TlmVI; n=1; Streptoalloteichus hindusta... 161 5e-38
UniRef50_Q8PFQ6 Cluster: ATP-dependent serine activating enzyme;... 161 9e-38
UniRef50_Q311J0 Cluster: Amino acid adenylation; n=2; Bacteria|R... 161 9e-38
UniRef50_A4BLS1 Cluster: Putative non-ribosomal peptide synthase... 161 9e-38
UniRef50_Q5MP00 Cluster: OnnI; n=1; symbiont bacterium of Theone... 160 1e-37
UniRef50_Q0YRE6 Cluster: Amino acid adenylation; n=1; Chlorobium... 160 1e-37
UniRef50_Q0LN51 Cluster: Amino acid adenylation; n=1; Herpetosip... 160 1e-37
UniRef50_A3YFF7 Cluster: Amino acid adenylation; n=1; Marinomona... 160 1e-37
UniRef50_A0IQF4 Cluster: Amino acid adenylation domain; n=2; Ent... 160 1e-37
UniRef50_O68007 Cluster: Bacitracin synthetase 2 (BA2) [Includes... 160 1e-37
UniRef50_Q93GY4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 160 2e-37
UniRef50_O69146 Cluster: Peptide synthetase; n=1; Bacillus subti... 160 2e-37
UniRef50_Q93H42 Cluster: Non-ribosomal peptide synthetase; n=1; ... 159 2e-37
UniRef50_Q8Y8D4 Cluster: D-alanine--poly(phosphoribitol) ligase ... 159 2e-37
UniRef50_Q2T4N2 Cluster: Thiotemplate mechanism natural product ... 159 3e-37
UniRef50_UPI000038DECD Cluster: COG1020: Non-ribosomal peptide s... 159 3e-37
UniRef50_A1TTI8 Cluster: Amino acid adenylation domain; n=1; Aci... 159 3e-37
UniRef50_Q4KAY8 Cluster: Pyochelin synthetase F; n=1; Pseudomona... 158 5e-37
UniRef50_Q8GAQ3 Cluster: BarG; n=1; Lyngbya majuscula|Rep: BarG ... 158 5e-37
UniRef50_Q0S5F4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 158 5e-37
UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9; Ba... 158 5e-37
UniRef50_P27743 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 158 5e-37
UniRef50_Q9KIZ9 Cluster: EpoB; n=2; Sorangium cellulosum|Rep: Ep... 158 6e-37
UniRef50_Q08QA2 Cluster: Linear gramicidin synthetase subunit B;... 158 6e-37
UniRef50_A1ZVW4 Cluster: Linear gramicidin synthetase subunit B;... 158 6e-37
UniRef50_A1CLY8 Cluster: Hybrid NRPS/PKS enzyme, putative; n=1; ... 158 6e-37
UniRef50_Q70C44 Cluster: Non-ribosomal peptide synthase; n=1; Xa... 157 8e-37
UniRef50_Q5ZPA8 Cluster: TubD protein; n=4; cellular organisms|R... 157 8e-37
UniRef50_A1ZLW0 Cluster: Bacitracin synthetase 1 (BA1), putative... 157 8e-37
UniRef50_A1G2S2 Cluster: Amino acid adenylation domain; n=1; Sal... 157 8e-37
UniRef50_Q2UNQ1 Cluster: Polyketide synthase modules and related... 157 8e-37
UniRef50_Q0TGG3 Cluster: Non-ribosomal peptide synthetase; n=5; ... 157 1e-36
UniRef50_A7BWG0 Cluster: Non-ribosomal peptide synthetase; n=2; ... 157 1e-36
UniRef50_A4D935 Cluster: CrpC; n=1; Nostoc sp. ATCC 53789|Rep: C... 157 1e-36
UniRef50_A0ZF80 Cluster: Peptide synthetase; n=3; Nostocaceae|Re... 157 1e-36
UniRef50_Q606X9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 157 1e-36
UniRef50_Q9LAS7 Cluster: Putative uncharacterized protein; n=1; ... 157 1e-36
UniRef50_Q8U9P4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 156 2e-36
UniRef50_Q1DCS5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 156 2e-36
UniRef50_Q1D591 Cluster: Nonribosomal peptide synthetase; n=1; M... 156 2e-36
UniRef50_P94873 Cluster: Alpha-aminoadipyl-cysteinyl-valine synt... 156 2e-36
UniRef50_Q4KAY7 Cluster: Pyochelin synthetase E; n=1; Pseudomona... 156 2e-36
UniRef50_Q1I8N8 Cluster: Putative pyoverdine sidechain peptide s... 156 2e-36
UniRef50_A5N8Z4 Cluster: Predicted hybrid nonribosomal peptide s... 156 2e-36
UniRef50_A1D6D2 Cluster: Nonribosomal peptide synthase GliP2; n=... 156 2e-36
UniRef50_Q2SIL6 Cluster: Non-ribosomal peptide synthetase module... 155 4e-36
UniRef50_Q20CI8 Cluster: CesB; n=7; cellular organisms|Rep: CesB... 155 4e-36
UniRef50_A3NJZ9 Cluster: CtaG; n=12; pseudomallei group|Rep: Cta... 155 4e-36
UniRef50_A7TDA1 Cluster: Predicted protein; n=2; cellular organi... 155 4e-36
UniRef50_Q93H70 Cluster: Non-ribosomal peptide synthetase; n=1; ... 155 6e-36
UniRef50_A4X8P7 Cluster: Amino acid adenylation domain; n=1; Sal... 155 6e-36
UniRef50_Q48D76 Cluster: Non-ribosomal peptide synthetase; n=1; ... 154 8e-36
UniRef50_Q2T5X7 Cluster: Peptide synthetase, putative; n=9; Burk... 154 8e-36
UniRef50_Q7CRI7 Cluster: AGR_L_3476p; n=2; Agrobacterium tumefac... 154 8e-36
UniRef50_Q333V2 Cluster: NRPS protein; n=1; Micromonospora sp. M... 154 8e-36
>UniRef50_Q402E3 Cluster: Ebony; n=4; Neoptera|Rep: Ebony - Papilio
xuthus
Length = 861
Score = 1204 bits (2983), Expect = 0.0
Identities = 562/772 (72%), Positives = 654/772 (84%), Gaps = 6/772 (0%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
+TIM LLA + GAAYVPM+PSFPQG I+HILKDAEPSLVIYD++A+PSMF SG+P S
Sbjct: 90 NTIMTLLAIMEGGAAYVPMDPSFPQGGISHILKDAEPSLVIYDNTANPSMFSGSGIPAVS 149
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
F+EL+ EA+ D+P D+E L T++SIAIVLYTSGSTGIPKGVRL YSAICNRLWWQ
Sbjct: 150 FDELSLEASGLPGDKPSDSEMLLQTTAESIAIVLYTSGSTGIPKGVRLPYSAICNRLWWQ 209
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI----- 192
FRTFPY++ E CVWKTALTFVDSVCEIWGPLLHGR L+ILSRETTRDPQKLV +
Sbjct: 210 FRTFPYTEHERFCVWKTALTFVDSVCEIWGPLLHGRTLIILSRETTRDPQKLVRVLAENE 269
Query: 193 -ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
RLVLVPTLLRSILMYL+L + RPL+ LKLWVCSGETLSKELA +FF+YFG+ +GYKL
Sbjct: 270 VHRLVLVPTLLRSILMYLSLNRSERPLQSLKLWVCSGETLSKELAGQFFQYFGDNEGYKL 329
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
ANFYGSTEVMGDVT+YVLE S QLD++PTIPIG+P+DNCAIYLLDEE++P R++EPGEVW
Sbjct: 330 ANFYGSTEVMGDVTFYVLERSQQLDIHPTIPIGKPVDNCAIYLLDEEMNPAREAEPGEVW 389
Query: 312 VAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYAGRTDAQVKIR 371
VAG+NLAAGYVGG +FC NPHA+ P+F +LYRTGDFG L KG +LYAGRTD+QVKIR
Sbjct: 390 VAGSNLAAGYVGGQAPEKFCYNPHASHPDFGKLYRTGDFGVLHKGMILYAGRTDSQVKIR 449
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
GHRVDLLEVE A++ V G++K VVLCYGL+RGNPE+L FVT P AR SA HIE L+++
Sbjct: 450 GHRVDLLEVETAVSAVEGIEKAVVLCYGLERGNPEVLAFVTISPDARLSAHHIEAALKNS 509
Query: 432 LTHYMMPQVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
LTHYM+PQVI +E++PLLVNGKVDRQ LLKMYENTNNNDD+E++ DID +
Sbjct: 510 LTHYMLPQVIVIEAVPLLVNGKVDRQALLKMYENTNNNDDSEISFDIDYTGVEAEKLEAA 569
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
TVG VLGRAARGTLS+R+GFYELGGNSLNSIYTIT+LRDRGYY++IS+FLGA+ L
Sbjct: 570 KVLFETVGEVLGRAARGTLSVRAGFYELGGNSLNSIYTITRLRDRGYYIDISEFLGAANL 629
Query: 552 GEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMVESSFYEKAELEQFLKHEIETR 611
G+VL+ MS+ P+ + FTAV M ++H+++VIDM+ SSFYEKAELEQFLKHEIET
Sbjct: 630 GDVLAHMSSGPDHETGGYDHKFTAVAMNEDHEQQVIDMIVSSFYEKAELEQFLKHEIETE 689
Query: 612 DYADCIDACWPALLQAGLSVVLNDVNSEPVAVALNFDVRDEPEIELSGGLAKIMGFLEYV 671
DYA CI ACW ALLQA LSVVL D + PVAVALNFD RDEPEIEL+GGLAKIM FLE+V
Sbjct: 690 DYAHCIRACWAALLQARLSVVLEDHSGTPVAVALNFDARDEPEIELNGGLAKIMTFLEFV 749
Query: 672 EGSVRDTMLPHGKGAVLHSFMMATSERLSARDNVSAIRALELATDRVARQRRFRGVFTTN 731
E SVRDTMLP GKG +LHSFMMAT+ LS +DNV+AIRALE AT R+AR RRF GVFTTN
Sbjct: 750 ESSVRDTMLPEGKGTILHSFMMATASSLSPQDNVAAIRALEHATMRIARDRRFHGVFTTN 809
Query: 732 TSPLTQQLGTDILGFKTLLDYQINQYVDPNGERIFGKAPDDMRAIVCWKPLD 783
TSPLTQQLGTD+LGF+TLLDYQIN+Y+DPNG+RIFGKAPDDMRAIVCWKP++
Sbjct: 810 TSPLTQQLGTDVLGFQTLLDYQINEYIDPNGDRIFGKAPDDMRAIVCWKPIE 861
>UniRef50_O76858 Cluster: Ebony protein; n=18; Diptera|Rep: Ebony
protein - Drosophila melanogaster (Fruit fly)
Length = 879
Score = 767 bits (1897), Expect = 0.0
Identities = 385/780 (49%), Positives = 524/780 (67%), Gaps = 24/780 (3%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ LLA WKAG AY+P++PSFP RI HIL +A+P+LVI DD D F+ G P S
Sbjct: 101 VTTLLAIWKAGGAYLPIDPSFPANRIHHILLEAKPTLVIRDDDIDAGRFQ--GTPTLSTT 158
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL ++ + + E L +D AIVLYTSGSTG+PKGVRL + +I NRL WQ+
Sbjct: 159 ELYAKSLQLAGSNLLSEEMLRG-GNDHTAIVLYTSGSTGVPKGVRLPHESILNRLQWQWA 217
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
TFPY+ +E + V+KTALTFVDS+ E+WGPL+ G A+L++ + T+DPQ+LV I
Sbjct: 218 TFPYTANEAVSVFKTALTFVDSIAELWGPLMCGLAILVVPKAVTKDPQRLVALLERYKIR 277
Query: 194 RLVLVPTLLRSILMYLAL---GPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
RLVLVPTLLRS+LMYL + G A + L L++WVCSGE LS LAS FF YF +E ++
Sbjct: 278 RLVLVPTLLRSLLMYLKMEGGGAAQKLLYNLQIWVCSGEPLSVSLASSFFDYF-DEGVHR 336
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L NFYGSTEV+GDVTY+ E QL LY +PIG PL N +YLLD + P ++ E GE+
Sbjct: 337 LYNFYGSTEVLGDVTYFACESKKQLSLYDNVPIGIPLSNTVVYLLDADYRPVKNGEIGEI 396
Query: 311 WVAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYAGRTDAQVKI 370
+ +G NLAAGYV G RF +NP A + ++ RLYRTGD+G+L G+++Y GRTD+QVKI
Sbjct: 397 FASGLNLAAGYVNGRDPERFLENPLAVEKKYARLYRTGDYGSLKNGSIMYEGRTDSQVKI 456
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLR 429
RGHRVDL EVE+ +A++P VDK +VLCY + + IL FV + A + +E +L+
Sbjct: 457 RGHRVDLSEVEKNVAELPLVDKAIVLCYHAGQVDQAILAFVKLRDDAPMVTETQMEARLK 516
Query: 430 SALTHYMMPQVIEVESIPLLVNGKVDRQGLLKMYENTNNND-DAEVAVDIDCSXXXXXXX 488
L YM PQV+ +E +PLLVNGKVDRQ LLK YE NNN+ D+ + +D D S
Sbjct: 517 DKLADYMTPQVVILEHVPLLVNGKVDRQALLKTYETANNNEGDSSIVLDFDYSQVPEDLK 576
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
TVG V+GR+ TL S FYELGGNSLNSI+T+T LR++GY + IS+F+ A
Sbjct: 577 LTARDLFETVGGVIGRSTETTLPPHSNFYELGGNSLNSIFTVTLLREKGYNIGISEFIAA 636
Query: 549 STLGEVLSKMSTDPNGGADSKEA-------TFTAVPMRDEHKKEVIDMVESSFYEKAELE 601
LGE++ KM+ + + +E+ AVP+R EH++EVID++ +SFY KA+LE
Sbjct: 637 KNLGEIIEKMAANHDAVQLEEESLNACPHLKMEAVPLRLEHRQEVIDIIVASFYNKADLE 696
Query: 602 QFLKHEIETRDYADCIDACWPALLQAGLSVVLNDVNSEP-VAVALNFDVRDEPEIELSGG 660
Q+LK + DY+D ++ W L++ LS V+ D N++ + ALNFD R+EPE+++
Sbjct: 697 QWLKPGVLRTDYSDILNDIWNVLVERDLSFVVYDTNTDRIIGTALNFDARNEPEVDIKSK 756
Query: 661 LAKIMGFLEYVEGSVRDTMLPHGKGAVLHSFMMATSERLSARDNVSAIRALELATDRVAR 720
L + FLE+ EG +RD LP G +LHSFMM T+E+L+ R+N++ + +E RVAR
Sbjct: 757 LLIVFEFLEFCEGPIRDNYLPKGLNQILHSFMMGTAEKLNPRENIACMHFMEHEVLRVAR 816
Query: 721 QRRFRGVFTTNTSPLTQQLGTDILGFKTLLDYQINQYVDPNGERIFGKAPDDMRAIVCWK 780
+++F G+FTTNTSPLTQQL D+ +KTLL++Q+N+YV +G R FG APD+ RAIV WK
Sbjct: 817 EKQFAGIFTTNTSPLTQQL-ADVYHYKTLLNFQVNEYVHSDGSRPFGDAPDEQRAIVHWK 875
>UniRef50_UPI0000DB6BFA Cluster: PREDICTED: similar to ebony
CG3331-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to ebony CG3331-PA - Apis mellifera
Length = 860
Score = 684 bits (1691), Expect = 0.0
Identities = 343/770 (44%), Positives = 499/770 (64%), Gaps = 22/770 (2%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELA 82
L+A KAG AY+P++ FP R+ HIL++A+P +V+ + D S+++ G ++E+L
Sbjct: 98 LIAILKAGMAYLPLDAEFPMVRMKHILEEAKPFVVVIEQETDLSLYE--GTNTITYEQLL 155
Query: 83 QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFP 142
+++ + + E + AIVLYTSGSTGIPKGV L ++ I NRL WQ++ P
Sbjct: 156 KQSKNEEKENLKVEED-----PERTAIVLYTSGSTGIPKGVLLPHATILNRLEWQWQELP 210
Query: 143 YSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IERLV 196
Y++ E+ C++KT+LTFVDSV EIWGPLL GR L+++ + T+DP++ V+ I+RLV
Sbjct: 211 YAEDEKNCIFKTSLTFVDSVSEIWGPLLQGRTLVVVPKHVTKDPERFVSVLEEHKIQRLV 270
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
LVP+LL S+LMYL+L LR L+LWVCSGETL LA +FF F N D LANFYG
Sbjct: 271 LVPSLLHSMLMYLSLQNKDDVLRSLRLWVCSGETLPVSLADQFFTTFEN-DSKILANFYG 329
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
STE+MGDVTY++L QL +PIG+PLDNC IY++++++ E GE+ VAG N
Sbjct: 330 STEIMGDVTYHLLTNRKQLQSVEKVPIGKPLDNCVIYIVNKDMRLIPQGEVGELIVAGRN 389
Query: 317 LAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVD 376
LA GY+ + +F DNP+ E+ R+Y TGD+ + KG ++Y GR D+Q+K+RGHRVD
Sbjct: 390 LATGYIHNNESRKFQDNPYTIDLEYSRIYCTGDYAKISKGVIMYEGRVDSQIKVRGHRVD 449
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EVE+ ++++ +D +VLCY + ++ FVT + T IE L+S L YM
Sbjct: 450 LTEVEKVISRISEIDGVIVLCYKPGELSQSLVAFVTIAKDSSTCVSKIETFLQSMLPIYM 509
Query: 437 MPQVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXX 496
+P+VI VE+IPLL NGK DRQ LLK YE++N N++ E ++ D +
Sbjct: 510 LPRVIIVENIPLLTNGKTDRQALLKYYESSNVNNENEQCMNCDYTNVLEKDLAKAKVLFP 569
Query: 497 TVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEVLS 556
TV +V+G R ++L + FYELGGNSLNSIYT+TKLRD+GY + I++F+ A L EVL
Sbjct: 570 TVASVIGNGGRADITLNANFYELGGNSLNSIYTVTKLRDQGYEIGITEFITAKNLAEVLD 629
Query: 557 KM--STDP---NGGADSKEATFTAVPMRDEHKKEVIDMVESSFYEKAELEQFLKHEIETR 611
+M ST+ + +E F + D HKK+VI+++ SFY KA+LEQ+L +I
Sbjct: 630 RMKISTEDVVYENTLNEEEHIFEM--LNDSHKKDVIEIITESFYSKADLEQWLMPDITRE 687
Query: 612 DYADCIDACWPALLQAGLS-VVLNDVNSEPVAVALNFDVRDEPEIELSGGLAKIMGFLEY 670
DY ++ W +L++ LS VV + +++ + V LNFD+ DEPE+ L L + FLEY
Sbjct: 688 DYQIMMEMLWNSLVEKNLSFVVKSSQDNKTIGVGLNFDLWDEPELILDSKLMIVFEFLEY 747
Query: 671 VEGSVRDTMLPHGKGAVLHSFMMATSERLSARDNVSAIRALELATDRVARQRRFRGVFTT 730
+E +R+ LP GKG ++H+FMM TS L+ +NV ++ +E ++A+++ + G+FTT
Sbjct: 748 LEAPIRERKLPKGKGQIIHNFMMTTSSDLNPAENVIMMKEMEEYCLQLAKRKEYAGIFTT 807
Query: 731 NTSPLTQQLGTDILGFKTLLDYQINQYVDPNGERIFGKAPDDMRAIVCWK 780
NTSPLTQQLG D+ G++T+L YQ+N+Y P+G + F KAPDD AI K
Sbjct: 808 NTSPLTQQLGIDVFGYETMLTYQVNRYYAPDGTKPFEKAPDDQLAICSLK 857
>UniRef50_Q9GSP4 Cluster: Mutant e4 ebony; n=2; Drosophila|Rep:
Mutant e4 ebony - Drosophila melanogaster (Fruit fly)
Length = 735
Score = 504 bits (1243), Expect = e-141
Identities = 246/517 (47%), Positives = 345/517 (66%), Gaps = 11/517 (2%)
Query: 274 QLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDN 333
QL LY +PIG PL N +YLLD + P ++ E GE++ +G NLAAGYV G RF +N
Sbjct: 216 QLSLYDNVPIGIPLSNTVVYLLDADYRPVKNGEIGEIFASGLNLAAGYVNGRDPERFLEN 275
Query: 334 PHATQPEFQRLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKC 393
P A + ++ RLYRTGD+G+L G+++Y GRTD+QVKIRGHRVDL EVE+ +A++P VDK
Sbjct: 276 PLAVEKKYARLYRTGDYGSLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKA 335
Query: 394 VVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLRSALTHYMMPQVIEVESIPLLVNG 452
+VLCY + + IL FV + A + +E +L+ L YM PQV+ +E +PLLVNG
Sbjct: 336 IVLCYHAGQVDQAILAFVKLRDDAPMVTETQMEARLKDKLADYMTPQVVILEHVPLLVNG 395
Query: 453 KVDRQGLLKMYENTNNND-DAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLS 511
KVDRQ LLK YE NNN+ D+ + +D D S TVG V+GR+ TL
Sbjct: 396 KVDRQALLKTYETANNNEGDSSIVLDFDYSQVPEDLKLTARDLFETVGGVIGRSTETTLP 455
Query: 512 LRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEVLSKMSTDPNGGADSKEA 571
S FYELGGNSLNSI+T+T LR++GY + IS+F+ A LGE++ KM+ + + +E+
Sbjct: 456 PHSNFYELGGNSLNSIFTVTLLREKGYNIGISEFIAAKNLGEIIEKMAANHDAVQLEEES 515
Query: 572 -------TFTAVPMRDEHKKEVIDMVESSFYEKAELEQFLKHEIETRDYADCIDACWPAL 624
AVP+R EH++EVID++ +SFY KA+LEQ+LK + DY+D ++ W L
Sbjct: 516 LNACPHLKMEAVPLRLEHRQEVIDIIVASFYNKADLEQWLKPGVLRTDYSDILNDIWNVL 575
Query: 625 LQAGLSVVLNDVNSEP-VAVALNFDVRDEPEIELSGGLAKIMGFLEYVEGSVRDTMLPHG 683
++ LS V+ D N++ + ALNFD R+EPE+++ L + FLE+ EG +RD LP G
Sbjct: 576 VERDLSFVVYDTNTDRIIGTALNFDARNEPEVDIKSKLLIVFEFLEFCEGPIRDNYLPKG 635
Query: 684 KGAVLHSFMMATSERLSARDNVSAIRALELATDRVARQRRFRGVFTTNTSPLTQQLGTDI 743
+LHSFMM T+E+L+ R+N++ + +E RVAR+++F G+FTTNTSPLTQQL D+
Sbjct: 636 LNQILHSFMMGTAEKLNPRENIACMHFMEHEVLRVAREKQFAGIFTTNTSPLTQQL-ADV 694
Query: 744 LGFKTLLDYQINQYVDPNGERIFGKAPDDMRAIVCWK 780
+KTLL++Q+N+YV +G R FG APD+ RAIV WK
Sbjct: 695 YHYKTLLNFQVNEYVHSDGSRPFGDAPDEQRAIVHWK 731
Score = 101 bits (243), Expect = 6e-20
Identities = 54/111 (48%), Positives = 70/111 (63%), Gaps = 3/111 (2%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ LLA WKAG AY+P++PSFP RI HIL +A+P+LVI DD D F+ G P S
Sbjct: 101 VTTLLAIWKAGGAYLPIDPSFPANRIHHILLEAKPTLVIRDDDIDAGRFQ--GTPTLSTT 158
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAI 130
EL ++ + + E L +D AIVLYTSGSTG+PKGVRL + +I
Sbjct: 159 ELYAKSLQLAGSNLLSEEMLRG-GNDHTAIVLYTSGSTGVPKGVRLPHESI 208
>UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 2193
Score = 286 bits (701), Expect = 2e-75
Identities = 183/450 (40%), Positives = 248/450 (55%), Gaps = 29/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ +L KAG AYVPM+PS+P+ RI +L+D+ LV+ D E+ +
Sbjct: 584 VACILGILKAGGAYVPMDPSYPKARIAFMLEDSGLKLVL--TKKDILKGVETNAVMLCID 641
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E Q+ + S D P E A S S+A ++YTSGSTG PKGV+ + I NR W +R
Sbjct: 642 ECMQQISEESDDSP---ENKAD--SGSVAYIIYTSGSTGRPKGVQGLHKGIINRCNWMWR 696
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
T+PY + EEIC KTAL+FVDS+CEI+ PLL G L+I+ ET D Q V+ I
Sbjct: 697 TYPYKE-EEICCQKTALSFVDSICEIFSPLLKGIRLVIIPDETLLDVQHFVDELSVSRIS 755
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
R+VLVP+LL+++L + + L LKLWV SGETL EL F + N +L N
Sbjct: 756 RIVLVPSLLQAMLD--TVPDIGKKLSELKLWVTSGETLRIELMKRFKQSIPNG---RLIN 810
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YGS+EV DVTYY + + + +PIGRP+DN IY+LD P GE++VA
Sbjct: 811 IYGSSEVSADVTYY--DTALASETLSRVPIGRPIDNTEIYILDSNKQPVPIGVAGELYVA 868
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY+ RF NP+ T +YR GD L G + Y GR D QVKI
Sbjct: 869 GDGLAKGYLNRPELTEERFVPNPYDTS---GLMYRMGDMARYLPDGNIEYLGRGDNQVKI 925
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG RV+L E+E L + P V + VV+ YG +G+ + ++ + +R
Sbjct: 926 RGIRVELGEIESVLLKFPSVKEAVVVSYGELKGDVRLAAYIVPDVTV-PEVDELRSFIRG 984
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGL 459
L YM+P I VE IPLL NGK+D++ L
Sbjct: 985 YLPEYMIPVSINFVEHIPLLPNGKIDKKSL 1014
Score = 278 bits (682), Expect = 4e-73
Identities = 197/583 (33%), Positives = 296/583 (50%), Gaps = 45/583 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ +L KAG AYVP++PS+P+ RI +L+D+ LV+ D E+ +
Sbjct: 1644 VACILGILKAGGAYVPLDPSYPKERIAFMLEDSGLKLVL--TKKDILKGVETNAVMLCID 1701
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E Q+ + S D P E A S S+A ++YTSGSTG PKGV+ + I NR W +R
Sbjct: 1702 ECMQQISEESDDSP---ENKAD--SGSVAYIIYTSGSTGKPKGVQGLHKGIINRCNWMWR 1756
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
T+PY + EEIC KTAL+FVDS+CEI+ PLL G L+I+ ET D Q V+ I
Sbjct: 1757 TYPYKE-EEICCQKTALSFVDSICEIFSPLLKGIRLVIIPDETLLDVQHFVDELSVSRIS 1815
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
R+VLVP+LL+++L + + L LKLWV SGETL EL F + N +L N
Sbjct: 1816 RIVLVPSLLQAMLD--TVPDIGKKLSELKLWVTSGETLRIELMKRFKQSIPNG---RLIN 1870
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YGS+EV D TYY + + + +PIGRP+DN IY+LD GE++VA
Sbjct: 1871 IYGSSEVSADATYY--DTALASETLSRVPIGRPIDNTEIYILDSNKQLVPIGVAGELYVA 1928
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY+ RF NP+ T +YR GD L G + Y GR D QVKI
Sbjct: 1929 GDGLAKGYLNRPELTKERFVPNPYDTS---GLMYRMGDMARYLPDGNIEYLGRGDNQVKI 1985
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG RV+ E+E L + P V + VV+ YG +G+ + ++ + +R
Sbjct: 1986 RGIRVESGEIESVLLKFPSVKEAVVVSYGEAKGDVRLAAYIVPNVTV-PEVDELRSFIRG 2044
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L+ YM+P I VE +PLL NGK+D++ L ++ CS
Sbjct: 2045 YLSEYMIPASINFVEHMPLLPNGKIDKKSL-----PNPELLKGQLEFTPPCSEIEKEIAQ 2099
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGA 548
VLG G + + F+++GG+SL + I+++R + G +++ F +
Sbjct: 2100 MW-------NEVLGVKESG---INNSFFDMGGHSLMATQLISRIRLKFGVDLQLKSFFSS 2149
Query: 549 STLGEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMVE 591
T+ + + A S + + + ++++++M++
Sbjct: 2150 PTIKSIAKSVEDQILMDASSDQINDVLNLLEELSEEDILNMLD 2192
>UniRef50_Q0SKF6 Cluster: Non-ribosomal peptide synthetase; n=2;
Nocardiaceae|Rep: Non-ribosomal peptide synthetase -
Rhodococcus sp. (strain RHA1)
Length = 10372
Score = 248 bits (608), Expect = 3e-64
Identities = 162/447 (36%), Positives = 241/447 (53%), Gaps = 27/447 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A KAG AY+P++P P R H+L A+P+ V+ + + VP
Sbjct: 9560 LVAIYAVVKAGGAYLPVDPDHPAERTAHVLDTAQPACVLVSGAG---LAGGGSVPVI--- 9613
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
++A E S P+ DA+ L PL+ + A V++TSGSTG PKGV +++ AI NRL W
Sbjct: 9614 DVASEDVSGFDSSPVTDADRLWPLSPANTAYVIFTSGSTGRPKGVAVTHGAIVNRLLWMQ 9673
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
+ + S ++ + KT +TF SV E++ PL G +L+I + + RDP+ L + ER V
Sbjct: 9674 HEYTLT-SADVVLQKTPVTFDVSVWELFWPLQVGASLVIAAPDGHRDPRYLTGLIQERHV 9732
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ S+L PA L+L CSGE L+ E S F G + L N YG
Sbjct: 9733 TTTHFVPSMLSVFTAEPAVAVCDSLRLVFCSGEALTPEQVSRFRAVCGAD----LHNLYG 9788
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DVTY+ +D + T+PIGRP+ N +++LD L P + GE+++AG
Sbjct: 9789 PTEAAVDVTYWETGAADTV----TVPIGRPVWNTQVHVLDSRLHPVPNGVAGELYLAGDQ 9844
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGH 373
LA GY+ A+RF NPH R+YRTGD G + Y GRTD QVK+RG
Sbjct: 9845 LARGYLNRPDLSADRFVANPHVAG---GRMYRTGDLVRRRADGVLEYVGRTDFQVKLRGQ 9901
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E AL P V + VV+ + DRG ++ ++ A S + L + +
Sbjct: 9902 RIELGEIEAALEAHPDVSQAVVVVHRDDRGEEALVAYLVGPRAADWS--DVRAHLSARVP 9959
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P QV+ ++++PL NGK+DR L
Sbjct: 9960 SYMIPAQVVHLDTLPLSANGKLDRTAL 9986
Score = 224 bits (547), Expect = 8e-57
Identities = 174/551 (31%), Positives = 266/551 (48%), Gaps = 40/551 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A +AG AY+P++ + P R+ ++L A P + I S+D F VP +
Sbjct: 8494 LVGMYAVLRAGGAYLPIDLTHPADRLAYVLATARP-VCILTTSSDG--FAAESVPVIEID 8550
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + T + DA LAPL ++ A +++TSGSTG PKGV ++++AI N+L W+
Sbjct: 8551 TL--DHTGSPREPVTDARRLAPLRPENTAYLIFTSGSTGRPKGVAVTHAAIANQLRWKQH 8608
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ D+ + V KT +TF SV E++ PL G L+I + RDP L ++ R V
Sbjct: 8609 EYSL-DTTDAVVQKTPVTFDLSVWELFWPLTTGARLVIARPDGHRDPAYLADLMRQQRVT 8667
Query: 200 T--LLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T + S+L P + L+ +C GE L + A+ F + FG L N YG
Sbjct: 8668 TAHFVPSLLEAFLATPDAGEQPALRRVLCIGEALPVDTAARFRRRFGT---VALHNLYGP 8724
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE VT + +D +D T+PIG P N +++LD L+P GE+++AG L
Sbjct: 8725 TEAAVSVTAWT-HTADDVD---TVPIGGPEWNTQVFVLDARLNPVPVGVAGELYLAGEQL 8780
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL----VKGAVLYAGRTDAQVKIR 371
A GYV A RF NP RLYRTGD +G + Y R+D QVK+R
Sbjct: 8781 ARGYVARADLTAERFVANPFGASGS--RLYRTGDVVRWHVRDSRGVLEYLERSDFQVKVR 8838
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E AL GV + VV+ + ++G+V + GA + ++ +A
Sbjct: 8839 GFRIELGEIESALVSSAGVGQAVVVAHQHPHTGTTLIGYVVPEDGATVDFAAVLAEVGAA 8898
Query: 432 LTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
+ YM+P + V +PL NGK+DR+ L D A D
Sbjct: 8899 VPSYMVPAALVVLAQLPLTSNGKLDRRAL--------PAPDFASATD----EYRAPATPT 8946
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGAS 549
VLG GT + F++LGGNSL + + +L +R G VEI A
Sbjct: 8947 EEAVAAVFADVLGVDQVGT---AANFFDLGGNSLVATRVVARLSERLGCRVEIRTLFEAP 9003
Query: 550 TLGEVLSKMST 560
T+ + + + +
Sbjct: 9004 TVAALAALLDS 9014
Score = 215 bits (525), Expect = 4e-54
Identities = 169/554 (30%), Positives = 261/554 (47%), Gaps = 40/554 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A KAG AYVP++P P R +++L A+P V+ + P + + +P ++ +
Sbjct: 4234 VVGIYAVLKAGGAYVPVDPDHPAERTSYVLASAQPVCVLTTSADRPDL--PNRIPVSALD 4291
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + SA DAE + PL A V+YTSGSTG PKGV + ++AI N+L W
Sbjct: 4292 TL--DLSGVSAVPLTDAERIEPLRPAHPAYVIYTSGSTGKPKGVAVPHAAIVNQLLWMQS 4349
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ +D ++ + KTA TF S+ + PL G +++ + + R+P L + ER V
Sbjct: 4350 EYALTD-RDVWLQKTATTFDVSLWGYFWPLQVGATMVLATPDGHREPAYLTRVIDERAVT 4408
Query: 198 VPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + S+L +++A P R L+L GE L F + L N YG
Sbjct: 4409 VTDFVPSMLDVFVAAAPEGT-CRSLRLVFVIGEALPPATVLRFREL----SAAGLHNLYG 4463
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE VTY+ +D + +PIG P N Y+LD L P PGE+++ GA
Sbjct: 4464 PTEAAVSVTYWKTGDADTTN----VPIGVPEWNTQAYVLDSRLHPVPVGVPGELYLGGAQ 4519
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY+G ++RF NP E R+YRTGD GA++Y GRTD QVK RG
Sbjct: 4520 LARGYLGRVDLTSDRFVANPFGRTGE--RMYRTGDLVRWTSSGALVYIGRTDFQVKFRGQ 4577
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L P V VV Y ++ +V PG A+ + + +L
Sbjct: 4578 RIELGEIETVLRSHPAVTGAVVSVYSDTTVGDHLVAYVVGTPGELDVAE-LRRQASESLP 4636
Query: 434 HYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P I V + PL +GK+DR+ L + ++ +
Sbjct: 4637 SYMVPSAITVLDEFPLNTSGKLDRKELPAPEFHGSSTE------------YIAPRNEAER 4684
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD-RGYYVEISDFLGASTL 551
VLG + G F++LGGNSL+ +L + G + + D A T+
Sbjct: 4685 TVAAVFADVLGSSRVGA---HDNFFDLGGNSLSVTRVAARLGELSGTGLSVRDVFTAPTV 4741
Query: 552 GEVLSKMSTDPNGG 565
E+ +++ G
Sbjct: 4742 AELARRLAEPTAAG 4755
Score = 213 bits (520), Expect = 2e-53
Identities = 166/546 (30%), Positives = 258/546 (47%), Gaps = 38/546 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A KAG AYVP++P P RI ++L A+P V+ SAD +G F +
Sbjct: 1623 LVGMYAIVKAGGAYVPVDPDHPTDRIGYVLDSAQPVCVL-TTSADRGALP-AGQSFVEID 1680
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+A + S+S D++ LAPL D+ A V+YTSGSTG PKGV + + I N+L W
Sbjct: 1681 RIALD--SYSGGPVTDSDRLAPLRPDNPAYVIYTSGSTGRPKGVSVPHRGIVNQLLWMQS 1738
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ ++ ++ + KTA TF S+ + PL G +++ + + RDP+ L + E V
Sbjct: 1739 EYALTE-RDVLLQKTATTFDVSLWGYFWPLHTGATMVLATPDGHRDPEYLARVIDEHGVT 1797
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + S+L L+ GE L E + F ++ G L N YG
Sbjct: 1798 VTDFVPSMLDAFVASVPITSCSTLRHVFVIGEALPPETVTRFRAL--SDAG--LHNLYGP 1853
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE VTY+ + T+PIG P N +Y+LD L P GE+++AG L
Sbjct: 1854 TEAAVSVTYW----DTATTVAGTVPIGVPEWNTQVYVLDSRLHPVPPGVAGELYLAGEQL 1909
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY+G ++RF NP P R+YRTGD GA+ Y GRTD QVK RG R
Sbjct: 1910 ARGYLGRVDLTSDRFVANPFT--PGL-RMYRTGDLVRWTSAGALEYIGRTDFQVKFRGQR 1966
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L P V VL + ++ +V +PG + ++L
Sbjct: 1967 IELGEIEFVLRAQPSVTSAAVLVHSDPGTGDRLVAYVVPEPGHDLDTTRLRECAAASLPA 2026
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P ++ V+ PL +GK+DRQ L + + ++ +
Sbjct: 2027 YMIPAALMVVDEFPLNTSGKLDRQALPAPEFGGSGTEYVAPRTSVEAN------------ 2074
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEISDFLGASTLG 552
VLG + LR F+++GGNSL + +++R + G + + D A T+G
Sbjct: 2075 LAEIFAEVLG---LDRIGLRDNFFDVGGNSLVATRVTSRIRAELGAPLALRDLFDAPTVG 2131
Query: 553 EVLSKM 558
+ ++
Sbjct: 2132 ALAERI 2137
Score = 176 bits (429), Expect = 2e-42
Identities = 150/555 (27%), Positives = 259/555 (46%), Gaps = 48/555 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL A ++GAAYVP++ P R+ H+++ A P LV+ + +SGV +
Sbjct: 2685 LIALHAVLRSGAAYVPLDVDLPAERVAHVIEAAHPVLVL--TAVRGEFESDSGVRVLPID 2742
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L + D P+ + + L PL +D++A V++TSGSTG PKGV +S++ + + +
Sbjct: 2743 GLELDRFD---DAPVTNRDRLRPLAADNLAYVIFTSGSTGRPKGVAVSHAGLGSHFEFLM 2799
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIERL 195
+++ + V KT +F S+ E+ PL G ++I + +DP +L++ E++
Sbjct: 2800 SLCALDETDRVVV-KTPQSFDASLWELLWPLAVGARVVIAEPDGHKDPDYLAELIDTEQI 2858
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + + ++ + SR L+ GE LS +A + F + N Y
Sbjct: 2859 TAIHFVPSMLAVFTDVIAPSR-FSSLRTVFVGGEALSVNVA----RRFAAVSDAAVLNAY 2913
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G EV T ++ S+ + +G P+ N Y+LD+ L P+ GE+++AG
Sbjct: 2914 GPAEVAAASTTSWVDTSNS----AIVTVGTPVWNTRAYVLDQRLHPSPAGVTGELYLAGT 2969
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRG 372
++ GY G A RF NP R+YRTGD +G + Y GR D QVK+RG
Sbjct: 2970 QVSRGYAGRPDLTAERFVANPF--DAPGTRMYRTGDRLRWTGRGELEYLGRNDFQVKLRG 3027
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+E L V + VV Y + +++ ++ + G R + + S L
Sbjct: 3028 LRIELGEIEAVLESADSVAQAVVTVYS-GAASEQLVAYLVARAGTRVDIEALTAYAASRL 3086
Query: 433 THYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P + +++ PL +GK+DR L D E ++ S
Sbjct: 3087 PEYMVPDGFVTLDAFPLNASGKLDRVALPAPAVGDVAVDRVEPRTPMEESL--------- 3137
Query: 492 XXXXXTVGAVLGRAARGT--LSLRSGFYELGGNSLNSIYTITKLRDRGYYV---EISDFL 546
A L R A G L + F+ LGG+S+ SI +++ + G ++ +
Sbjct: 3138 --------AALFREALGVDDLGVNDSFFALGGDSIVSIQLVSRAKAAGIVFTPRDVFERK 3189
Query: 547 GASTLGEVLSKMSTD 561
+ L EV++ S D
Sbjct: 3190 SIAALAEVVTVASAD 3204
Score = 151 bits (366), Expect = 7e-35
Identities = 142/563 (25%), Positives = 240/563 (42%), Gaps = 44/563 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+ A K GAA+VP++P++P RI H+L D+ +L + + +
Sbjct: 5293 SVLAVWAVAKTGAAFVPVDPNYPAERIAHMLGDSGSALGLTTIEFRAGLPDSTQWLVMDD 5352
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ TSHS+ A+ L + +D +A ++YTSGSTG+PKGV +++S + N L
Sbjct: 5353 PDHTALVTSHSSAAVTAADRLGRMHADQLAYLIYTSGSTGLPKGVAVTHSGLANLLTELA 5412
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ + + + +F SV E G ++++ + + L+
Sbjct: 5413 DEYELTADARTLHFASP-SFDASVFEYLMAFCRGATMVVVPHSVYGGTE----LAELLGA 5467
Query: 199 PTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + AL L L + V GE +LA + G L N YG
Sbjct: 5468 QGVTHAFFTPAALASVDHTGLDELAVIVVGGEAWGADLAERWVP------GRALFNGYGP 5521
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE VT S L L + IG P+ ++LD L P PGE++++G L
Sbjct: 5522 TESSMMVTQ-----SGPLMLGERMTIGAPVRGVEAFVLDARLHPVSPGVPGELYISGPAL 5576
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG-----AVLYAGRTDAQVKI 370
A GY G A RF NPH +R+YRTGD V+ + Y GR+D QVKI
Sbjct: 5577 ARGYHQRLGLTAERFVANPHGAPG--RRMYRTGDLVRWVESRTGTYVIEYVGRSDFQVKI 5634
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG RV+L E++ V + + + G ++ +V G + +
Sbjct: 5635 RGFRVELGEIDSVFRAHSAVGFAATIAHDTESGVTALVTYVCAASGNDVDVDDLTAFVGG 5694
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L +M+P ++ ++SIPL GK+DR+ L + V + +
Sbjct: 5695 VLPAHMVPGSIMVLDSIPLTPAGKLDRRALPE-------------PVFVSHTRFTAPDTA 5741
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGA 548
VLG + G + F+ LGGNSL++ ++++ G V +
Sbjct: 5742 DEIAVAAAFADVLGESRIG---VDDNFFALGGNSLSATQVVSRVGSAFGTRVSVRTLFDN 5798
Query: 549 STLGEVLSKMSTDPNGGADSKEA 571
T+ +++S ++T + + A
Sbjct: 5799 PTVRQLVSAVATSGPDASSGRPA 5821
Score = 148 bits (359), Expect = 5e-34
Identities = 144/574 (25%), Positives = 253/574 (44%), Gaps = 50/574 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+ A K GAA+VP++P +P R+ H+++D+ ++V SA + +S + +
Sbjct: 7433 SVVAVWAVAKTGAAFVPVDPGYPADRVLHMVQDSG-AMVGITVSAKQDVLPDS-IRWMLL 7490
Query: 79 EE--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
++ LA T S + + + P+ SD +A V+YTSGSTG PKGV +++ + N +
Sbjct: 7491 DDPALAVRCTHESRLPLTNRDRMRPILSDQVAYVIYTSGSTGRPKGVAVTHRGLMNLVTD 7550
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+ + + + +F SV E+ L G A ++++ T +L L+
Sbjct: 7551 ERELLGVTSGSRTLHFASP-SFDASVFEMLMALGAG-ATMVIAPPTIYGGSELAE---LL 7605
Query: 197 LVPTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + AL L L + V +G+ EL + + G ++ N Y
Sbjct: 7606 AAEHVTHAFSTPAALASVDHHGLDDLAVVVVAGDVCPPELVARW------APGRRMVNAY 7659
Query: 256 GSTE--VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
G +E +M +T + G + IG P +LD L P PGE++V
Sbjct: 7660 GPSEATIMSSITEPLRAGEP-------VTIGGPSRGVRALVLDGRLRPVPVGVPGELYVG 7712
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKI 370
G +LA GY+G G A RF +P+ + +YRTGD + VL + GRTD QVKI
Sbjct: 7713 GPSLARGYLGRPGLTAERFVADPYGEPGDL--MYRTGDLVRWRENRVLDFVGRTDHQVKI 7770
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E++ AL P ++ + Y G ++ +V G + +
Sbjct: 7771 RGFRIELGEIDAALTAHPQIEYATTIGYEHPNGETSLVAYVLPFTGEDVDRVEVANFVGR 7830
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P V ++++PL GK+DR A + I +
Sbjct: 7831 TLPAYMVPASVTLLDALPLTPAGKLDR---------------AALPEPIFVAAATTFEAP 7875
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGA 548
G A + + F++LGGNSL + ++++ +V + + +
Sbjct: 7876 RNPMEVIVAGIFADILALPEIGIHDSFFDLGGNSLLATQVVSRINAALDVHVGVREVFES 7935
Query: 549 STLGEVLSKMSTDPNGGADSKEATFTAVPMRDEH 582
T+ + ++++ G + TA P R EH
Sbjct: 7936 PTVAALAARITETTTHGV--RRPALTAKP-RPEH 7966
Score = 140 bits (339), Expect = 1e-31
Identities = 138/464 (29%), Positives = 213/464 (45%), Gaps = 45/464 (9%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++ + A K GAAYVP++P+ P RI HIL+D+ +V+ A+ + +
Sbjct: 6355 SVLCVWAAAKTGAAYVPIDPAHPADRIAHILRDS--GVVVGVTCAEFAEHLPGVTDWLVL 6412
Query: 79 EELA--QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
++ A +E +S S DA+ + L D A ++YTSGSTG+PKGV +S+ + N L
Sbjct: 6413 DDPAVLRELSSASTAPVGDADRTSALHVDHPAYLIYTSGSTGLPKGVVVSHRGLAN-LAG 6471
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ--KLVNIER 194
+ T + E + TF SV E+ G AL++ + +++ ER
Sbjct: 6472 SYTTAVRATEESRVAHLASPTFDLSVLELLLAHTSGAALVVCPPGVYGGVELHEVLQSER 6531
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ + T+ + L ++ P L L+ V G+ E + + D +L N
Sbjct: 6532 VTHM-TITNAALA--SVEPEG--LDDLRSIVVGGDACPPETVARW------ADRLELVNG 6580
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TEV T+ + G + I IG PL A +LD L P GE+++ G
Sbjct: 6581 YGPTEVTVGATFSSVLGQGR-----DITIGGPLPGVAAVVLDSRLRPVPVGVVGELYLLG 6635
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF----------------GTLVKG 356
LA GY A+RF +P + R+YRTGD GT
Sbjct: 6636 PALARGYHERAALTAHRFVASPF--EAAGARMYRTGDIVRWRAVHSGVTGSMTDGTFPGH 6693
Query: 357 AVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG 416
A+ Y GR+D QVK+RG R++L E++ AL P V+ L Y + V G
Sbjct: 6694 AIEYLGRSDHQVKVRGLRIELGEIDAALNAHPDVEFAATLGYE-SPAETRLASHVLVGAG 6752
Query: 417 ARTSAQHIEGKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
A + LR AL YM+P ++ +++IPL NGK+DR L
Sbjct: 6753 ADRDPAALLAFLRQALPGYMVPSALVFLDTIPLTPNGKLDRDAL 6796
Score = 138 bits (333), Expect = 7e-31
Identities = 126/452 (27%), Positives = 206/452 (45%), Gaps = 32/452 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
++ ++ A KAGAA+VP++PS P RI +L+D + I + + + +
Sbjct: 559 SVSSVWAVAKAGAAFVPVDPSLPADRIAFMLEDCGAPIGITTAALRDGLPECTHWIVLDD 618
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+E A ++ D D + L+ D A V+YTSGSTG PKGV +++ + N +
Sbjct: 619 DEFRATAAAYPPDAVTDTDRTRALSVDHPAYVIYTSGSTGRPKGVAVTHRGVVNLAADER 678
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
S + + + +F SV E+ + G A L+++ T +L L+
Sbjct: 679 DRLVVSSGSRVLHFASP-SFDASVFELVMAVCAG-ATLVVAPTTIYGGTELAE---LMAE 733
Query: 199 PTLLRSILMYLALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + AL R L L+ V +G+ EL + + G + N YG
Sbjct: 734 QRVTHAFCTPAALASLDHRGLDHLRTVVVAGDVCPPELVARW------APGRIMVNAYGP 787
Query: 258 TE--VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
+E +M T ++ G + +G P + +LD L P GE++V G+
Sbjct: 788 SETTIMSSATGPMVPGQP-------VTVGSPTVGVDLVVLDHRLRPVPAGVRGELYVLGS 840
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGA----VL-YAGRTDAQV 368
+LA GYV G A RF +P T R+YRTGD V VL + GR+D QV
Sbjct: 841 SLARGYVRRAGLTAERFVASPFGTGG---RMYRTGDVVRWVTAPDGPPVLEFLGRSDFQV 897
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG R++L E++ AL P V+ + Y G+ ++ +V P + + +
Sbjct: 898 KIRGFRIELGEIDAALTAHPVVEFAYTVGYDDGSGSSRLVSYVLPVPATDVETRVLSEFV 957
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P ++ ++S+PL GK+DR L
Sbjct: 958 GERLPGYMVPSSIMMLDSLPLTPAGKLDRNAL 989
>UniRef50_Q8VQF9 Cluster: Peptide synthetase XpsA; n=1; Xenorhabdus
bovienii|Rep: Peptide synthetase XpsA - Xenorhabdus
bovienii
Length = 1089
Score = 245 bits (600), Expect = 3e-63
Identities = 158/451 (35%), Positives = 240/451 (53%), Gaps = 25/451 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLV-IYDDSADPSMFKESGVPFASF 78
++ LL KAGAAYVP++P +P R+ +IL D++P+L+ I+ D V
Sbjct: 546 VIGLLGILKAGAAYVPLDPEYPTDRLGNILSDSDPALLLIHHGLQDHLPMTTMPVWVLES 605
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
EE S D P+ + LTS +A VLYTSGSTG+PKGV + + NRL W
Sbjct: 606 EEYRTNIASQPTDNPVATDL--GLTSRHLAYVLYTSGSTGLPKGVMNEHRGVVNRLLWAQ 663
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------I 192
+ + + + + KT +F SV E + PLL G L++ ++ L+ I
Sbjct: 664 DEYQLTQHDRV-LQKTPFSFDVSVWEFFLPLLAGTQLVMARPGGHKEALYLLEEIEARGI 722
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L VP++L+S ++ L PA R L+ +CSGE LS L + +F + + L
Sbjct: 723 TTLHFVPSMLQS---FIHLTPAGR-CPSLRQILCSGEALSYSLQQQCLAHFAHSE---LH 775
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE DVT + + L +PIG P+DN IY+LD+ P GE+++
Sbjct: 776 NLYGPTEAAIDVTSWRCVPDQHIGL---VPIGHPIDNTQIYILDKHDQPVPIGVIGEIYI 832
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
AGA +A GY+ A RF +P + P+ R+Y+TGD G L G++ Y GR D QVK
Sbjct: 833 AGAGVARGYLNKPELTAERFIRDPFSQHPDM-RMYKTGDIGRWLADGSIDYLGRNDFQVK 891
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG+R++L E+E LAQ GV +V+ D G+ ++ ++ KPG S + ++
Sbjct: 892 IRGNRIELGEIEARLAQSDGVQNVIVIAREYDAGDTRLVAYLIPKPGVTLSIPALREQVG 951
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+L YM+P + +++ PL +NGK+DR+ L
Sbjct: 952 GSLPDYMIPSAFVMLDAFPLTLNGKLDRKAL 982
>UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3;
cellular organisms|Rep: Non-ribosomal peptide synthetase
- Erwinia carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 7048
Score = 238 bits (582), Expect = 5e-61
Identities = 175/545 (32%), Positives = 265/545 (48%), Gaps = 44/545 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP++P +P R+ ++L DA P ++ A+ VP +
Sbjct: 2733 VIGLLAILKAGAAYVPLDPGYPAERLAYMLDDASPVALL--TQANQRALLTGDVPRILLD 2790
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S D P + L + +A V+YTSGSTG PKGV S+ A+CNRL W
Sbjct: 2791 --TADFSHLSEDNPH----VPGLDAHHLAYVIYTSGSTGKPKGVMNSHRALCNRLVWMQN 2844
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
T+ + + + + KT +F SV E + PLL+G L++ + +D L IER
Sbjct: 2845 TYRLTPDDRV-LQKTPFSFDVSVWEFFWPLLYGARLVMARPDGHKDAAYLAQLIERTGIT 2903
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L+ + + A LRR+ +CSGE L EL FF F + L N
Sbjct: 2904 TLHFVPSMLQQFVQWADADCACDSLRRV---ICSGEALPAELQQRFFARFNAQ----LHN 2956
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ + D +PIGRP+ N +Y+LD P GE+ +
Sbjct: 2957 LYGPTEAAIDVTFWACQPDDHRSF---VPIGRPIANTQLYILDTLDQPVPLGVAGELHIG 3013
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ A RF +P QP RLY+TGD L G++ Y GR D QVK+
Sbjct: 3014 GVGVARGYLNRPDLTAERFIPDPFINQPG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKL 3072
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L Q PGV + VV+ G+ ++ ++ +PG + +L
Sbjct: 3073 RGFRIELGEIEARLMQCPGVQEAVVVAREDSPGDTRLVAYLCPQPGITPDPADLRQQLGQ 3132
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P + +++ PL NGK+DR+ L D + VA +
Sbjct: 3133 HLAEYMVPGAFVTLDAFPLTPNGKLDRKAL-------PAPDQSAVATRDYEAPQGEVETA 3185
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
+G L R R F+ LGG+SL ++ I +LR+ G +++ A
Sbjct: 3186 LAAVWQDLLG--LTRVGR-----HDHFFALGGHSLMAVSLIERLRNAGLTLDVRSIFSAP 3238
Query: 550 TLGEV 554
L ++
Sbjct: 3239 VLSDM 3243
Score = 231 bits (564), Expect = 7e-59
Identities = 152/450 (33%), Positives = 231/450 (51%), Gaps = 30/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP++P +P R+ ++L DA P ++ A+ +P +
Sbjct: 5972 VIGLLAILKAGAAYVPLDPGYPAERLAYMLDDARPVALL--TQANQRALLTGDIPVVMLD 6029
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S D P + L + +A V+YTSGSTG PKGV S+ +CNRL W
Sbjct: 6030 --TADFSHLSEDNPH----VVGLDAHHLAYVIYTSGSTGKPKGVMNSHRGLCNRLVWMQN 6083
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
T+ + + + + KT +F SV E + PLL+G L++ + +D L IER
Sbjct: 6084 TYRLTPDDRV-LQKTPFSFDVSVWEFFWPLLYGARLVMARPDGHKDAAYLAQLIERTGIT 6142
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L+ + + A LRR+ +CSGE L EL FF F + L N
Sbjct: 6143 TLHFVPSMLQQFVQWADADCACDSLRRV---ICSGEALPAELQQRFFARFNAQ----LHN 6195
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ + D +PIGRP+ N +Y+LD P GE+ +
Sbjct: 6196 LYGPTEAAIDVTFWACQPDDHRSF---VPIGRPIANTQLYILDTLGQPVPLGVAGELHIG 6252
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ A RF +P + Q RLY+TGD L G++ Y GR D QVK+
Sbjct: 6253 GVGVARGYLNRPDLTAERFIPDPFSNQ-HGARLYKTGDLARWLPDGSLEYLGRNDFQVKL 6311
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L Q PGV + VV+ G+ ++ ++ +P + +L +
Sbjct: 6312 RGFRIELGEIEARLMQCPGVQEAVVVAREDSPGDTRLVAYLCPQPSIELMPAELRQQLST 6371
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + +++ PL NGK+DR+ L
Sbjct: 6372 HLADYMIPSAFVMLDTFPLTPNGKLDRKAL 6401
Score = 214 bits (523), Expect = 7e-54
Identities = 170/548 (31%), Positives = 263/548 (47%), Gaps = 29/548 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LLA KAGAAY+P++PS+P R+T++L DA P + + SA + ++ +P +
Sbjct: 568 IIGLLAILKAGAAYLPLDPSYPAERLTYMLDDATP-VALLTQSALTATLPDTALPTVLLD 626
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + D DA L +T D +A V+YTSGSTG PKGV + ++++ RL +
Sbjct: 627 --AHDVFDAQPDHNPDAHALG-VTPDHLAYVIYTSGSTGKPKGVMVEHASV-TRLLDATQ 682
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + DS ++ + F SV EIWG L +G L+++ R PQ+ ++ V
Sbjct: 683 DYFHFDSNDVWTQFHSFAFDFSVWEIWGALAYGGKLVVVPTLCARSPQEFYSLLCRERVT 742
Query: 200 TLLRSILMYLALGPASRPL-RRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L ++ + L A L+ + GE L + + + E +L N YG T
Sbjct: 743 VLNQTPGAFRQLIAARDDTDHSLRCIIFGGEALELHMLAPWIADNPLERT-RLINMYGIT 801
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E+ T+ L +D ++ IGRPL + YLLD P GE+++ GA +A
Sbjct: 802 EITVHATFRELSAADITAGRGSL-IGRPLPDLRAYLLDPHGQPVPVGVAGELYIGGAGVA 860
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +P + P RLY+TGD L G + Y GR D QVK+RG R+
Sbjct: 861 RGYLNRPDLTAERFIVDPFSDSPA-TRLYKTGDLARWLPDGTLDYLGRNDFQVKVRGFRI 919
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E L Q PGV + VVL G+ ++ ++ +P A + +L + L Y
Sbjct: 920 ELGEIESRLVQCPGVQEAVVLAREDVPGDTRLVAYIQPQPKAVLEPADLRQQLSTHLADY 979
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAV-DIDCSXXXXXXXXXXXX 493
M+P + +E+ PL NGK+DR+ L + E V DI+ +
Sbjct: 980 MIPAAFVTLEAFPLTPNGKLDRKALPAPERSAVVTRGYEEPVGDIETALAEIWQD----- 1034
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
+LG G F+ELGG+SL + I KLR G +++ A TL E
Sbjct: 1035 -------LLGLERVGRY---DHFFELGGHSLLIVSLIEKLRHLGLKLDVRSVFTAPTLIE 1084
Query: 554 VLSKMSTD 561
+ + D
Sbjct: 1085 LADAIQHD 1092
Score = 211 bits (516), Expect = 5e-53
Identities = 161/539 (29%), Positives = 265/539 (49%), Gaps = 34/539 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGAAYVP++PS+P R+T++L+D+ P ++ S S+ S P +
Sbjct: 4885 VIGLLGILKAGAAYVPLDPSYPTERLTYMLEDSAPVALLTHSSLVASL--SSTAPTILLD 4942
Query: 80 ELAQ-EATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A EA S S P A+ + LT +A ++YTSGSTG PKGV + + I + +
Sbjct: 4943 NTALFEACSDS--NPA-AQAIG-LTPHHLAYIIYTSGSTGKPKGVMVEHRNIVASTYARQ 4998
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
T+P E + +++ F ++ ++G L G +L + +E T DP ++++ E +
Sbjct: 4999 LTYPMF---ERVLLLSSIAFDSALASVFGTLTRGGSLYLPQQEITVDPTAILHMLHEHHI 5055
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ S+ + L + L LK + +GE E+ + + G L N YG
Sbjct: 5056 CCLLCVPSLALSLLQMSQNEELASLKALIVAGERCPPEIQTAI-EQLGLSTA--LYNEYG 5112
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE + Y + ++ T+PIG P+ N IY+LD + PT + GE+++ GA
Sbjct: 5113 PTEAAVWASVYHVTSTETSRNRLTVPIGHPIANSQIYILDPQGRPTLLNVAGEIYIGGAG 5172
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ A RF +P ++ PE R+Y+TGD L G + Y GR D QVK+RG
Sbjct: 5173 VARGYLNRPDLTAERFIPDPFSSSPE-ARMYKTGDLARWLPDGNIDYLGRNDFQVKVRGF 5231
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L Q+PGV + VV G+ ++ ++ ++P A + + +L L
Sbjct: 5232 RIELGEIESRLMQLPGVQEAVVAAREDIPGDTRLVAYLRSQPDAELNPTELRQQLAEHLA 5291
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P + +++ PL NGK+DR+ L D + VA +
Sbjct: 5292 EYMVPSAFVTLDTFPLTPNGKIDRKAL-------PAPDHSAVATRGYVTPQGELETALAQ 5344
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
+G L R R F+ELGG+SL ++ I +LR+ G +++ A L
Sbjct: 5345 IWQDLLG--LDRVGR-----HDQFFELGGHSLMAVSLIERLRNIGQTLDVRSVFSAPIL 5396
Score = 194 bits (474), Expect = 6e-48
Identities = 134/446 (30%), Positives = 220/446 (49%), Gaps = 24/446 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAGAAYVP++P++P R+ ++L DA+P ++ + ++ S +P +
Sbjct: 1656 IVGLLGILKAGAAYVPLDPAYPAERLAYMLDDAKPVALLTQTALIETL--NSTLPLVVLD 1713
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ H++ + DA L LTS +A V+YTSGSTG PKGV + + ++CN Q R
Sbjct: 1714 DPQFTVFKHASQDNPDAHALG-LTSHHLAYVIYTSGSTGQPKGVMIEHRSLCNLANAQIR 1772
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + + + + + +F + E+ L G +L++ SRE L+N + +
Sbjct: 1773 AFGITANSRLLQF-ASFSFDACISEVTTTLCQGASLILASREALLPGDALLNTLQTQAIT 1831
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + AL ++ P L + +GE LA + ++ N YG TE
Sbjct: 1832 HVTLPPIAAGALDASAEP-PDLTTLIFAGEACPPALAKRW------ATAKQVINAYGPTE 1884
Query: 260 --VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
V + +Y G D L PIG+P+DN +Y+LD + GE+++ G +
Sbjct: 1885 STVCATIYHYHRTGDDFL------PIGKPIDNTHVYILDAKGQLAPLGVAGEMYLGGVGI 1938
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF +P++ QP R+Y+TGD G L G + Y GR D Q+K+RG R
Sbjct: 1939 ARGYLNRPELTAERFIPDPYSDQPG-ARMYKTGDLGRWLADGNIEYLGRNDFQIKLRGFR 1997
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++ E+E L GV VV+ + + ++ ++ GA + +L L
Sbjct: 1998 IEPGEIEARLMGCSGVQDAVVIVREDNPNDKRLVAYIRPHVGAEIEPAALRLQLSQHLAE 2057
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + +E PL NGK+DR+ L
Sbjct: 2058 YMLPAAFVTLEQFPLTPNGKLDRKAL 2083
Score = 186 bits (454), Expect = 2e-45
Identities = 153/539 (28%), Positives = 236/539 (43%), Gaps = 36/539 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +LA KAG AYVP++PS+P R+T++L+DA P ++ D S +P +
Sbjct: 3811 IVGMLAVLKAGGAYVPLDPSYPADRLTYMLEDAAPVALL--TQTDLVALLHSDLPVIELD 3868
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L D + LT +A V+YTSGSTG PKGV + + ++CN L Q
Sbjct: 3869 NLPAAIADEGQDSNPVPQAFG-LTPRHLAYVIYTSGSTGKPKGVMVEHRSMCNLLNGQIE 3927
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + + + + +F + E + LL G L + R L + +
Sbjct: 3928 SLHIAADSHV-IQLASFSFDVCMQECYMTLLTGATLYLAERAAILPGAAL---RQTLEDN 3983
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
T+ ++ AL L+ V GE L + G + N YG TE
Sbjct: 3984 TITHMLITPTALAALDEIPETLQTLVVGGEICPPALVKRWAA------GRCMFNAYGPTE 4037
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
T Y D+ + P I GRPL N IY+LD + GE+ + G +A
Sbjct: 4038 TTVCATLYPCRIQDERE--PCI--GRPLANTRIYILDPQGKLVPIGATGEIHIGGVGVAR 4093
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ A F +P P+ RLY+TGD G L G + Y GR D QVK+RG R++
Sbjct: 4094 GYLNRPELTAEHFIADPFTDDPD-ARLYKTGDLGRWLNDGNIDYLGRNDFQVKVRGFRIE 4152
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L E+E L Q GV + V + G ++ ++ +PG + +L L YM
Sbjct: 4153 LGEIEARLIQCSGVKEAVAIAREDTPGETRLVAYLIAQPGVELVPAELRQQLAHHLAEYM 4212
Query: 437 MPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXX 495
+P + +E+ PL NGK+DR+ L + + T A V +
Sbjct: 4213 VPSAFVTMEAFPLTPNGKLDRKA-LPVPDQT-----AIVTRTYEAPVGEKETILASIWQH 4266
Query: 496 XTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEV 554
+GR R F+ELGG+SL ++ I +LR+ GY +++ TL ++
Sbjct: 4267 LLGLTHVGR--------RDQFFELGGHSLMAVNLIERLRNLGYRLDVRSVFSLPTLADM 4317
>UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3;
Bacteria|Rep: Non-ribosomal peptide synthetase - Erwinia
carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 7523
Score = 235 bits (574), Expect = 4e-60
Identities = 156/450 (34%), Positives = 232/450 (51%), Gaps = 30/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP++P +P R+ ++L DA P ++ A+ VP +
Sbjct: 5893 VIGLLAILKAGAAYVPLDPGYPAERLAYMLDDASPVALL--TQANQRALLTGDVPRILLD 5950
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S D P + L + +A V+YTSGSTG PKGV S+ A+CNRL W
Sbjct: 5951 --TADFSHLSEDNPH----VPGLDAHHLAYVIYTSGSTGKPKGVMNSHRALCNRLVWMQN 6004
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
T+ + + + + KT +F SV E + PLL+G L++ + +D L IER
Sbjct: 6005 TYRLTPDDRV-LQKTPFSFDVSVWEFFWPLLYGARLVMARPDGHKDAAYLAQLIERTGIT 6063
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L+ + + A LRR+ +CSGE L EL FF F + L N
Sbjct: 6064 TLHFVPSMLQQFVQWADADCACDSLRRV---ICSGEALPAELQQRFFARFNAQ----LHN 6116
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ + D +PIGRP+ N +Y+LD P GE+ +
Sbjct: 6117 LYGPTEAAIDVTFWACQPDDHRSF---VPIGRPIANTQLYILDTLGQPVPLGVAGELHIG 6173
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ A RF +P QP RLY+TGD L G++ Y GR D QVK+
Sbjct: 6174 GVGVARGYLNRPDLTAERFIPDPFINQPG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKL 6232
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L Q PGV + VV+ G+ ++ ++ +PG + +L
Sbjct: 6233 RGFRIELGEIEARLMQCPGVQEAVVVAREDSPGDTRLVAYLCPQPGVTPDPADLRQQLGQ 6292
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P + +++ PL NGK+DR+ L
Sbjct: 6293 HLAEYMVPGAFVTLDAFPLTPNGKLDRKAL 6322
Score = 233 bits (571), Expect = 1e-59
Identities = 154/450 (34%), Positives = 232/450 (51%), Gaps = 30/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP++P +P R+ ++L DA P ++ A+ S +P +
Sbjct: 2684 VIGLLAILKAGAAYVPLDPGYPAERLAYMLDDARPVALL--TQANQSALLTGDIPVVMLD 2741
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S D P +A L + +A V+YTSGSTG PKGV S+ +CNRL W
Sbjct: 2742 --TADFSHLSEDNPH----VAGLDAHHLAYVIYTSGSTGKPKGVMNSHRGLCNRLVWMQN 2795
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
T+ + + + + KT +F SV E + PLL+G L++ + +D L IER
Sbjct: 2796 TYRLTPDDRV-LQKTPFSFDVSVWEFFWPLLYGARLVMARPDGHKDAAYLAQLIERTGIT 2854
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L+ + + A LRR+ +CSGE L EL FF F + L N
Sbjct: 2855 TLHFVPSMLQQFVQWADADCACDSLRRV---ICSGEALPAELQQRFFARFNAQ----LHN 2907
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ + D +PIGRP+ N +Y+LD P GE+ +
Sbjct: 2908 LYGPTEAAIDVTFWACQPDDHRSF---VPIGRPIANTQLYILDTLGQPVPLGVAGELHIG 2964
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ RF +P + QP RLY+TGD L G++ Y GR D QVK+
Sbjct: 2965 GVGVARGYLNRPDLTVERFIPDPFSNQPG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKL 3023
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L Q PGV + VV+ G+ ++ ++ + G + +L
Sbjct: 3024 RGFRIELGEIEARLMQCPGVQEAVVVAREDSPGDTRLVAYLCPQLGVTPDPADLRQQLGQ 3083
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P + +++ PL NGK+DR+ L
Sbjct: 3084 HLAEYMVPGAFVTLDAFPLTPNGKLDRKAL 3113
Score = 205 bits (501), Expect = 3e-51
Identities = 160/543 (29%), Positives = 254/543 (46%), Gaps = 34/543 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAGAAYVP++PS+P R+T++L+DA P + + +A ++ +S +P +
Sbjct: 3762 IVGLLGILKAGAAYVPLDPSYPVDRLTYMLEDAAP-VALLTQTALVTLL-DSPLPVIELD 3819
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + D + LT + +A V+YTSGSTG PKGV + + ++CN +
Sbjct: 3820 NLPAAIADETPDSNPTPQAFG-LTPNHLAYVIYTSGSTGKPKGVMVEHRSLCNLVDALAD 3878
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + + + + +F V E+ L HG L++ RE + L+ + V
Sbjct: 3879 AFNITRDSRLLQF-ASFSFDACVFEVATTLSHGGCLVLAPREALLPGEALLTTLKTQAVT 3937
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + AL P+ L LK + GE + A++ ++ G ++ N YG TE
Sbjct: 3938 HALLPPIAASAL-PSDAELPLLKTLILGGEACT---AAQVKRW---ASGRRVFNAYGPTE 3990
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ T + S T PIGRP+ N IY+LDE+ P GE+++ GA +A
Sbjct: 3991 ITVCATLSCCDASHN----GTPPIGRPIANTQIYILDEQKQPVPLGVAGEIYIGGAGVAR 4046
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ A RF +P P+ RLY+TGD G L G + Y GR D Q+K+RG R++
Sbjct: 4047 GYLNRPELTAERFIADPFTDTPD-ARLYKTGDLGRWLPNGDIDYLGRNDFQIKLRGFRIE 4105
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L E+E L Q GV + VV+ G+ ++ ++ +PGA + +L L YM
Sbjct: 4106 LGEIETHLIQCSGVGEAVVIAREDSTGDARLVAYLCPQPGAELHPTDLRQQLSRHLAEYM 4165
Query: 437 MPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXX 495
+P + ++ PL NGK+DR L + D E +
Sbjct: 4166 VPSAFVVLDVFPLTSNGKLDRNALPAPGQTAVARHDYE-------APQGELEIALAQIWQ 4218
Query: 496 XTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEVL 555
+G L R R F+ELGG+SL + I +LR+ G+ E L ++
Sbjct: 4219 DLLG--LDRVGR-----HDQFFELGGHSLIIVRLIERLRNLGWTPEARSLFSTPILCDMA 4271
Query: 556 SKM 558
++
Sbjct: 4272 QEI 4274
Score = 199 bits (485), Expect = 3e-49
Identities = 148/452 (32%), Positives = 226/452 (50%), Gaps = 36/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P++P R+ ++L DA+P +I SA + S +P +
Sbjct: 6971 VVGLLGILKAGGAYVPLDPTYPVERLRYMLDDAKPVALI-SQSAHLGIMNGS-LPVILLD 7028
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + D P+DA LT +A V+YTSGSTG PKGV + ++ + N L R
Sbjct: 7029 DGETRPFDNEPDTPLDARKQG-LTPRHLAYVIYTSGSTGKPKGVMVEHANMVNFLC-SMR 7086
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
P E++ + T+L+F S+ EI+ PLL+G L++ ++ D Q+L IER
Sbjct: 7087 KEPGIAQEDVLLGVTSLSFDISILEIFLPLLNGARLILATQAQAADAQQLAMLIERHAVS 7146
Query: 195 -LVLVPTLLRSI--LMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ P+ R + L AL P + L C GE L + LA+ + L
Sbjct: 7147 FMQATPSTWRMLVELRDFALPPGFKAL-------CGGEALPENLATALLQKVTT-----L 7194
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE + L G PT IG P+ N IY+LD + GE+
Sbjct: 7195 WNLYGPTET---TIWSTLNGLTT----PTPYIGHPIANTQIYILDAQGRVVPLGVAGEIH 7247
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
+AGA + GY+G A RF +P + PE R+Y+TGD G L G + Y GR D QV
Sbjct: 7248 IAGAGVVRGYLGRPDLTAERFITDPFSGAPE-ARMYKTGDLGRWLPDGTLEYLGRNDFQV 7306
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L E+E LA+ GV VV+ G+ ++ ++ +P + +L
Sbjct: 7307 KVRGFRIELGEIETRLARCHGVHDAVVIAREDSPGDKRLVAYLLAQPDTVLEPADLRQRL 7366
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ YM+P + +++ PL NGK+DR+ L
Sbjct: 7367 SEGVAEYMIPSAFVTLDAFPLTPNGKLDRKAL 7398
Score = 185 bits (450), Expect = 5e-45
Identities = 137/452 (30%), Positives = 223/452 (49%), Gaps = 32/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGAAYVP++PS+P R+ ++L DA+P ++ S S S P +
Sbjct: 1623 VVGLLGILKAGAAYVPLDPSYPAERLAYMLDDADPVALLTHSSLIESFSHTS--PTIVLD 1680
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A P + L + +A ++YTSGSTG PKGV + + + N + W
Sbjct: 1681 NAAPFDAC-----PDTNPVIQGLNAAHLAYIIYTSGSTGKPKGVMVEHRGLSNYIQWARE 1735
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ S+S + V + + F +V ++ PLL G + ++ D Q+L + +L
Sbjct: 1736 YYVTSNSLDSIV-SSPVAFDATVTSLYLPLLCGGKIQLI-----HDGQELTELLPALLAT 1789
Query: 200 ---TLLRSILMYLA-LGPASRPLRRL---KLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
TL++ +LA LG + R+ L+V GE LS + + G ++
Sbjct: 1790 QPGTLIKITPTHLAALGQELQSTHRVCPDLLFVVGGEALSSATVALWQTL---SSGSRII 1846
Query: 253 NFYGSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE V+G +T+ + D +PIGRP+ N IY+LD + P GE++
Sbjct: 1847 NEYGPTETVVGCITFDACTPNSLTD---NVPIGRPIANTCIYILDAKGQPAPVGVAGEIY 1903
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
+ GA +A GY+ A RF +P + Q +Y+TGD G L G + Y GR D Q+
Sbjct: 1904 IGGAGVARGYLNRPDLTAERFIADPFSDSENAQ-IYKTGDLGRWLPDGNIEYLGRNDFQI 1962
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++ E+E L PGV + +V+ G+ ++ ++ +PG+ + L
Sbjct: 1963 KVRGFRIEPGEIEARLMAYPGVREALVIAREDSPGDIRLVAYLIAQPGSELIPSVLRKAL 2022
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + +++ PL NGK+DR+ L
Sbjct: 2023 ALHLAEYMVPSAFVTLDAFPLTPNGKLDRKAL 2054
Score = 184 bits (448), Expect = 8e-45
Identities = 153/548 (27%), Positives = 259/548 (47%), Gaps = 51/548 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ L+ K+GAAYVP++P++P R+ +++ DA+P ++ A+ + + +P +
Sbjct: 546 VVGLMGILKSGAAYVPLDPTYPAERLAYMIDDAKPVALL--TQANQIAIQTADIPAIMLD 603
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +A ++ P DA+ L +TS +A V+YTSGSTG PKGV +++ + N
Sbjct: 604 TDSFDA--YATSNP-DAQALG-VTSTHLAYVIYTSGSTGKPKGVMVTHRNVLNLASGLKT 659
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
+ S I + ++ F D+ + W +L G L+I+ D ++L + I+
Sbjct: 660 LLAFEHSNRIAL-NASIVF-DASVQNWIQILSGHTLVIVPDAIRTDARQLWHYFSHHAID 717
Query: 194 RLVLVPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
P L+ +L L P +P + L G+ +S+ + S + +
Sbjct: 718 LFDCTPVQLQWLLDAGLGTDPDYQPAQVL----IGGDAISQGIWSRLQQLTDT----RFI 769
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE D T ++ S PTI GRPL N +Y+L + P GE+++
Sbjct: 770 NVYGPTECTVDATACPIDSSQSA---PTI--GRPLTNTEVYILGTQGQPVPIGVTGEIYI 824
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVK 369
GA +A GY+ A RF NP + E RLY+TGD G G++ Y GR D QVK
Sbjct: 825 GGAGVARGYLNRPDLTAERFITNPFVDEQE-ARLYKTGDLGYWRHDGSITYLGRNDFQVK 883
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++L E+E L Q PG+ + VV+ G+ ++ + +P + + + +L
Sbjct: 884 LRGFRLELGEIETLLIQYPGIQEAVVILREDIPGDKRLVAYFQAQPDTQPTPADLRLQLS 943
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
L YM+P + +++ PL NGK+DR+ L + D S
Sbjct: 944 QRLAEYMIPSAFVALDAFPLTPNGKLDRKAL----------------PEPDKSAMVTRHY 987
Query: 489 XXXXXXXXTVGAVLGRAARGT--LSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
T+ A + + G +S F+ELGG SL + I +LR++G +++
Sbjct: 988 EAPQGEMETMLASIWQTLLGIDHVSRYDHFFELGGQSLMVVSLIEQLRNQGKTLDVRSAF 1047
Query: 547 GASTLGEV 554
A L E+
Sbjct: 1048 SAPVLYEM 1055
Score = 173 bits (422), Expect = 1e-41
Identities = 137/451 (30%), Positives = 215/451 (47%), Gaps = 35/451 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGAAYVPM+P++P R+ +IL DA P + + SA + S +P +
Sbjct: 4838 MVGLLGILKAGAAYVPMDPAYPAERLAYILDDAAP-VALLTQSAQVAQLN-STLPTVLLD 4895
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A A P + L + +A V+YTSGSTG PKGV +++ + N L
Sbjct: 4896 TPAAAAC------PDTNPVVQGLHAAHLAYVIYTSGSTGRPKGVMVAHRNVIN-LATGLH 4948
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
T D ++ F D+ + W LL G L+++ D +L ++
Sbjct: 4949 TLLALDHPSRIALNASIVF-DASVKNWIQLLSGHTLVLVPDALRADAHQLWRYFARHAVD 5007
Query: 194 RLVLVPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
P L+ +L L PA +P + L GE +S + S +
Sbjct: 5008 LFDCTPVQLQWLLDAGLGSDPAYQPAQVL----IGGEAISPAVWSRLQSLSDT----RFI 5059
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE D T V++ + L PTI G+PL N +Y+LD + P GE+ +
Sbjct: 5060 NVYGPTECTVDATACVVDRTQPL---PTI--GKPLANTRLYILDAQDQPVPIGVTGELHI 5114
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
GA +A GY+ A RF +P + P R+Y+TGD L G + Y GR D Q+K
Sbjct: 5115 GGAGVARGYLHRPDLTAERFIPDPFSADPA-ARIYKTGDLARWLPDGNIDYLGRNDFQIK 5173
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++ E+E L + PGV VV+ G+ ++ ++ +P A + +L
Sbjct: 5174 VRGFRIEAGEIESRLLRCPGVQDAVVIAREDSPGDTRLVAYLCARPDAELHPAALRQQLA 5233
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
++L YM+P + ++++PL NGK+DR+ L
Sbjct: 5234 ASLADYMIPSAFVTLDALPLTPNGKLDRKAL 5264
>UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Putative
non-ribosomal peptide synthetase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 2385
Score = 233 bits (570), Expect = 1e-59
Identities = 184/571 (32%), Positives = 264/571 (46%), Gaps = 41/571 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+L K+GAAYVP++P P RI +L DA P+ ++ D + + VP
Sbjct: 531 VVAVLGVLKSGAAYVPIDPDHPADRIRFVLGDAAPAALVA--GGDLAELPDVRVPLFHVT 588
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A S + D P A +AP D A V+YTSGSTG PKGV +S+ +
Sbjct: 589 -----APSSADDSPAGAPQVAPPDVDQPAYVIYTSGSTGTPKGVVVSHRNVVGLFAATES 643
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
F + E++ + F SV E+WGPLLHG L+++ RE TR P + + E V
Sbjct: 644 LFQFGP-EDVWTLFHSYAFDFSVWELWGPLLHGGRLVVVPREVTRSPADFLRLLAEHRVT 702
Query: 198 VPTLLRSILMYLALGPASRP--LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
V S L+ A P L++ V GE L + +++ G+ L N Y
Sbjct: 703 VLNQTPSAFEELSRADADAPGTALALRVVVFGGEALEPTRLASWYERHGDSTPL-LVNMY 761
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE V+Y L+GS P IGR L + YLLDE L P D GE++V GA
Sbjct: 762 GITETTVHVSYLALDGSHATS--PASAIGRGLPGLSTYLLDEALRPVPDGVVGELYVGGA 819
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRG 372
LA GY+G G A RF +P E RLYRTGD G + Y GR D QVKIRG
Sbjct: 820 QLARGYLGRPGLTATRFVADPFGAPGE--RLYRTGDLARRAGDGRLEYVGRADDQVKIRG 877
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++ E+ LA P V +C V+ +G ++ +V G + G L + L
Sbjct: 878 FRIEPAEISSVLATHPDVSRCAVVARHGAQGGAYLVVYVV---GESVDPAALRGYLAARL 934
Query: 433 THYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
+M+P +E+ES+PL NGK+DR+ L E + E A D +
Sbjct: 935 PEHMVPAAFVELESLPLTGNGKLDRRA-LPAPEFGSTAPSREPATDTE------------ 981
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYV---EISDFLG 547
VLGR + + F+ LGG+SL + ++++R R G + + D
Sbjct: 982 RVLAELFADVLGRDEGTPVGVDESFFSLGGHSLLATRLVSRIRSRLGQEIGVRAVFDHPT 1041
Query: 548 ASTLGEVLSKMSTDPNGGADSKEATFTAVPM 578
+ L V+ TD S + T +P+
Sbjct: 1042 VAGLARVVEGTDTDLRPSPQSADRRPTRLPL 1072
Score = 212 bits (517), Expect = 4e-53
Identities = 151/448 (33%), Positives = 227/448 (50%), Gaps = 24/448 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA + GAA+ P+EPS P R+ + + + LV+ + + + GV +
Sbjct: 1593 VVALLAVLRCGAAFAPVEPSLPAARVAELCRTSGTRLVLTTQAGRADLPELDGV-----D 1647
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA + +A+ P + E PLT D++A V+YTSG+TG KG + + IC RL WQ R
Sbjct: 1648 VLAVDGDEAAAEPPAEHEVRPPLTGDNLAYVIYTSGTTGRQKGAMIRHRPICFRLLWQAR 1707
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ + ++K L F SV EI+ PL+ G ++I RD ++L+ I E V
Sbjct: 1708 LLGFGPG-DAALFKAPLGFDISVNEIFLPLVTGARVVIAEPGVERDAEQLLEIIREHRVT 1766
Query: 198 VPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L+ S+L + L L LK C GE L+ EL + F + + Y + YG
Sbjct: 1767 FAYLVSSVLDVMLGLPGIEDVAGSLKHVWCGGEALTPELFARFRRQLADSVMY---HGYG 1823
Query: 257 STEVMGDVTY-YVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
E V++ + G+++ ++ IGRP N +Y+LDE L P GE++VAG
Sbjct: 1824 PAEATIGVSHEFYRPGTER----ASVSIGRPNPNTRMYVLDEHLQPVPVGVQGELYVAGL 1879
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRG 372
L GYV A+RF +P P +R+YRTGD G L + GR D QVKIRG
Sbjct: 1880 QLGRGYVNAPALTASRFVADPFG--PAGERMYRTGDLACWTAGGTLEFRGRADHQVKIRG 1937
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
RV+L EVE L++ P V + VV+ R + +L T + + G LR L
Sbjct: 1938 MRVELQEVESVLSEHPAVRQAVVVT-ARSRSDVGLLVAYCTTTDESVTGDGLRGWLRGRL 1996
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGL 459
+M+P V+ + PL+ +GKVDR+ L
Sbjct: 1997 PEHMVPAAVVCLPRFPLMPSGKVDRRSL 2024
>UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - Nostoc
sp. ATCC 53789
Length = 3735
Score = 233 bits (569), Expect = 2e-59
Identities = 173/556 (31%), Positives = 265/556 (47%), Gaps = 44/556 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P +PQ R+T +L DA+ S+++ + + +
Sbjct: 2730 VVGLLGILKAGGAYVPLDPEYPQERLTFMLADAQVSVLLTQQHLVEKLPRHQARVVHLDK 2789
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A S S + P +A + + ++A V+YTSGSTG PKGV LS+S +CN ++W
Sbjct: 2790 DWVAIAKS-SQENP-----IAQVQASNVAYVIYTSGSTGQPKGVILSHSNLCNHMFWMQA 2843
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
TFP + +++ + KT F SV E + PLL G LLI D L+ + ++ V
Sbjct: 2844 TFPLTKEDKV-LQKTPFGFDASVWEFYAPLLAGGQLLIAEPRGHTDSAYLLRLIAQQQVT 2902
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L+ S+L L LK C GE L L ++ L N YG
Sbjct: 2903 TIQLVPSLLQMLLEQGGIETCHSLKHVFCGGEVLPVTLQESLL----SKLDVNLHNLYGP 2958
Query: 258 TEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE D T++ + Q ++YP IPIGRP+DN IY+LD+ L P PGE+ + GA
Sbjct: 2959 TEACIDATFW----NCQREIYPQLIPIGRPIDNTQIYILDQNLQPVPVGVPGELHIGGAG 3014
Query: 317 LAAGYVG--GGGANRFCDNP--------HATQPEFQRLYRTGDFGT-LVKGAVLYAGRTD 365
LA GY+ +F NP +RLY+TGD L G + Y GR D
Sbjct: 3015 LAKGYLNLPELTQEKFIPNPFQGSRGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRID 3074
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
QVKIRG R++L E+E AL+Q V VV+ GN ++ +V +P + +
Sbjct: 3075 NQVKIRGFRIELGEIEAALSQHSDVQTSVVIVREDIPGNKRLVAYVVPQPQITPTVSQLR 3134
Query: 426 GKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXX 484
L+ L YM+P ++ +ES+PL NGK+DR+ L + E I+ S
Sbjct: 3135 SFLKEKLPEYMVPSAIVTLESLPLTPNGKIDRRAL----------PEPEARTGIESS--L 3182
Query: 485 XXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISD 544
+ + R + + + F+ELGG+S+ SI I++ + G + I
Sbjct: 3183 VAPRTPIEEKLTRIWEQVLRVEQ--IGIHDNFFELGGDSILSIQIISRAKVAGIELTIKQ 3240
Query: 545 FLGASTLGEVLSKMST 560
T+ ++ + T
Sbjct: 3241 LFANQTIAQLATVAGT 3256
Score = 196 bits (477), Expect = 2e-48
Identities = 137/450 (30%), Positives = 222/450 (49%), Gaps = 28/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P +PQ R++ IL+DA+ S+++ + P +
Sbjct: 1655 LVGLLGILKAGGAYVPLDPEYPQERLSFILEDAQVSVLLTQQHLVDKL------PECQAQ 1708
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ + + + + + ++ V+YTSGSTG PKGV++S++A+ N L +
Sbjct: 1709 LVSLDTNWQFISQLPQGNPITNVQASNLTYVIYTSGSTGQPKGVQISHTAVSNFLS-AMQ 1767
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P ++ + T ++F + EI+ P+ G L+I R+ T D ++L ++
Sbjct: 1768 QRPGITEQDTLLAVTTISFDIAALEIFLPITVGACLVIARRDVTLDGRELCDLLVKSKAT 1827
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + + L ++ LK+ +C GE L +L S+ + L N YG TE
Sbjct: 1828 IMQATPATWRLLLDSNYQFSDLKI-LCGGEALPWDLVSKLLARSAS-----LWNLYGPTE 1881
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ LE S+ L I IGRP+ N IY+LD+ L P PGE+ + GA LA
Sbjct: 1882 ATIWSSICQLESSESL-----ISIGRPISNTQIYILDQNLQPVPIGVPGELHIGGAGLAR 1936
Query: 320 GYVGGGGAN--RFCDNP------HATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GY+ +F NP + RLY+TGD L G + Y GR D QVKI
Sbjct: 1937 GYLKRPELTQEKFIPNPFEEAGGRGQEAGGSRLYKTGDLARYLPDGNIEYLGRIDNQVKI 1996
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E AL+Q P V V+ G+ ++ ++ +P + + L+
Sbjct: 1997 RGFRIELGEIEAALSQHPHVQASCVIAREDTPGDKRLVAYIVPQPQVTLTISELRSNLKE 2056
Query: 431 ALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
L YM+P I + ES+PL NGK+DR+ L
Sbjct: 2057 KLPDYMVPSAIVILESLPLTPNGKIDRRAL 2086
Score = 180 bits (438), Expect = 1e-43
Identities = 164/554 (29%), Positives = 249/554 (44%), Gaps = 61/554 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAE-PSLVIYDDSADPSMFKESGVPFASF 78
++ LL KAG AYVP++P +P+ R+ +L DA+ P L+ D E
Sbjct: 594 VVGLLGILKAGGAYVPLDPEYPKDRLNFMLADAQVPVLISQQRLLD--RLPEYQAKLICL 651
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+E+ E + + P++ + S +A V+YTSGSTG PKGV + +S +CN Q
Sbjct: 652 DEVWSEILQNKQNNPIEV-----VKSTDLANVIYTSGSTGKPKGVMVEHSGLCNLAQAQI 706
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL--- 195
+ F S + + + +F + EI L G L + ++++ L IERL
Sbjct: 707 QVFGLSGDSRVLQF-ASFSFDACISEILMALGSGARLYLGTKDSIMPGMPL--IERLKND 763
Query: 196 -VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ TL S L L + L L+ V +GE EL ++ K G N
Sbjct: 764 GITHVTLPPSALAVLPV----EELPTLQAIVVAGEACPLELMRQWSK------GRNFFNA 813
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE D+ I IGRP+ N IY+LD +L P PGE+ + G
Sbjct: 814 YGPTEASVCAAIAKCTPEDE-----KITIGRPIANAEIYILDSQLQPVPIGVPGELHIGG 868
Query: 315 ANLAAGYVGGGGAN--RFCDNPHATQPEF--------QRLYRTGDFGT-LVKGAVLYAGR 363
A +A GY+ +F NP + +RLY+TGD L G + Y GR
Sbjct: 869 AGVARGYLNRNELTQQKFIPNPFSRSRGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGR 928
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQH 423
D QVKIRG R++L E+E L+Q P V V+ G+ ++ ++ +P + +
Sbjct: 929 IDNQVKIRGFRIELGEIEATLSQHPHVQASCVIAREDIPGDKRLIAYIVLQPEQTATVKE 988
Query: 424 IEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSX 482
+ L+ L YM+P I + ES+PL NGK+DR+ L E T+ + VA
Sbjct: 989 LRSFLKEKLPEYMVPSAIAILESLPLTPNGKIDRRAL---PEPTSELSEKYVAPRTPIEE 1045
Query: 483 XXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
++GR F+ELGG+SL + I+++R R VEI
Sbjct: 1046 ILAVIWQQVLKL-----ELVGR--------HDNFFELGGHSLLATQFISRVRSR-LKVEI 1091
Query: 543 S--DFLGASTLGEV 554
S + A T+ E+
Sbjct: 1092 SLRELFAAPTIAEL 1105
>UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2;
cellular organisms|Rep: Nonribosomal peptide synthase -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 6675
Score = 232 bits (568), Expect = 2e-59
Identities = 157/447 (35%), Positives = 229/447 (51%), Gaps = 25/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AY+P++P +P+ R+ I+ DA S+V+ + + K V +
Sbjct: 108 MVALLAILKAGGAYLPLDPGYPEERLALIIDDAAVSVVLTQQRFEHRL-KAQAVEVICLD 166
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A E S D P A +P +A V+YTSGSTG PKG L + AICNRL W R
Sbjct: 167 DPASEELHPSEDNP--ASINSP---GDLAYVIYTSGSTGRPKGCMLPHKAICNRLLWMQR 221
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ +E I + KT TF SV E++ PLL G L++ E +D LV I + +
Sbjct: 222 HYQVGPAERI-LQKTPFTFDVSVWELFLPLLSGACLVMAKPEGHKDAHYLVQIIQAQQIT 280
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + S+L + PA R L SGE L+ +L +F +L N YG
Sbjct: 281 ICHFVPSMLRFFLKHPAVAECRSLSQVFVSGEALTHDLLLQFCSRLDA----RLHNLYGP 336
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ E +PIGRP+DN I++LD E P + GE+ + G L
Sbjct: 337 TEAAVDVTWWPAEPRPD----QRVPIGRPIDNIQIHILDAESHPVPIGQTGELCIGGVGL 392
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY+ A +F +P QP+ RLYRTGD + G + GR D+QVK+RG R
Sbjct: 393 ARGYLNRPELTAEKFIRDPFCAQPD-ARLYRTGDEARFLDDGQIEVLGRFDSQVKLRGFR 451
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L PG+ VVL +P+++ +V + + I +++ L
Sbjct: 452 IELGEIENTLKSHPGISDAVVLVQDPGSEDPKLVAYVVAQ---GLDKKTIRDFVKARLPE 508
Query: 435 YMMPQVIE-VESIPLLVNGKVDRQGLL 460
YM P ++ VE IP+ +GK DRQ LL
Sbjct: 509 YMTPNRVQFVEQIPVTAHGKTDRQALL 535
>UniRef50_Q0S3K6 Cluster: Non-ribosomal peptide synthetase; n=2;
cellular organisms|Rep: Non-ribosomal peptide synthetase -
Rhodococcus sp. (strain RHA1)
Length = 11258
Score = 232 bits (568), Expect = 2e-59
Identities = 177/559 (31%), Positives = 273/559 (48%), Gaps = 41/559 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++L A AG AYVP+EP P R ++++ A P+ V+ AD + VP E
Sbjct: 10253 VISLYAVHAAGGAYVPIEPEHPADRTSYVVDSAMPTCVL--SLADDIANLDVDVPVYLVE 10310
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + ++A D+E LA L D++A LYTSGSTG PKGV + ++A+ N+L W
Sbjct: 10311 DF--DLSEYAAGPVEDSERLAELRPDNLAYALYTSGSTGRPKGVAIPHAALANQLAWMRD 10368
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL---VNIERLV 196
+ ++++ + KT TF SV E++ PL+ G L+I S + RDP+ + V E +
Sbjct: 10369 VYGIG-AQDVVLQKTPFTFDASVWELFLPLVVGGTLVIASPDGHRDPEYMAATVGTEAVT 10427
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
++ + + M+L A R L+L GE L + A+E G+ + L N YG
Sbjct: 10428 VIQFVPSVLTMFLDAATADRS-GSLRLVFAGGEPLPQS-AAERVAGLGSAE---LVNLYG 10482
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TEV + T +V+E S + PIG P N Y+LD L+P PGE+++ GA
Sbjct: 10483 PTEVTINSTAHVVEPSGTATI---APIGSPAWNTRAYVLDAHLNPAPIGVPGELYLDGAQ 10539
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGH 373
LA GYV A RF NP R+YRTGD + VL + GRTD QVK+RG
Sbjct: 10540 LARGYVNSSALSAERFVANPF--DDSGARMYRTGDLVRWNENGVLEFVGRTDFQVKVRGL 10597
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L EVE A + V + V+ + + G ++ +V KP A A + G + +L
Sbjct: 10598 RIELGEVEEAFVRYRDVAQAAVIVHNSEVG-ARLVAYVVPKPDAALDAAALNGFVAESLP 10656
Query: 434 HYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P + V +PL +GK+DR+ L D +
Sbjct: 10657 EYMIPDSLMVLAELPLGTSGKLDRRAL--------------PVPDFASAAEFRAPSTDTE 10702
Query: 493 XXXXTV-GAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
TV G +LGR + G + F+ELGG+S+ SI + + R G + D T+
Sbjct: 10703 RALATVFGELLGRESVG---IDDSFFELGGDSIVSIQLVARARSAGIHFTARDVFERRTV 10759
Query: 552 GEVLSKMSTDPNGGADSKE 570
E+ + + + A +E
Sbjct: 10760 AELAAVADSGESAAAALQE 10778
Score = 208 bits (507), Expect = 6e-52
Identities = 149/447 (33%), Positives = 226/447 (50%), Gaps = 23/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A AG AY+P++P P R ++L+ A+P V+ + + E V + +
Sbjct: 7635 LVGMYAIAAAGGAYLPIDPDHPAERTAYVLESAQPVCVLATRAVVGGLPGE--VDYLLLD 7692
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
EL S P+ DAE + PL ++ A V+YTSGSTG PKGV +++ AI N+L W+
Sbjct: 7693 ELDLGGIDPS---PLTDAERITPLRPENAAYVIYTSGSTGRPKGVAIAHRAIANQLRWKQ 7749
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
+P + +E+ + KTA TF SV E W L G L++ + + RDP L + E+ V
Sbjct: 7750 SEYPLT-AEDSVLLKTAATFDLSVWEFWWALTAGARLVVATPDGHRDPSYLAALVAEQQV 7808
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ S+L L L +C GE L A ++ D ++ N YG
Sbjct: 7809 STVHFVPSLLSAFVAVAEPAQLVSLTRVLCIGEALP---ADTMLRFRDVSDA-EIFNLYG 7864
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE VT+Y D+ D ++PIGRP N Y+LD L P GE+++AG
Sbjct: 7865 PTEAAVSVTHY--RCGDERD--GSVPIGRPEWNTQTYVLDARLHPVPAGVTGELYLAGEQ 7920
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY G A RF NP R+YRTGD + G + Y GR+D QVK+RG
Sbjct: 7921 LARGYFGRHDLTAERFVANPFGDAG--HRMYRTGDLVRWNRDGNLDYVGRSDFQVKVRGF 7978
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+ERAL P V + VV+ + ++G+V + G + ++
Sbjct: 7979 RIELGEIERALVAHPSVAQAVVVVHHDRHTGDRLVGYVVPEQGVSVDDADVLTFAGRSVP 8038
Query: 434 HYMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM+P +I ++ +PL +NGK+DR+ L
Sbjct: 8039 GYMVPSALIALDVLPLNINGKLDRKAL 8065
Score = 202 bits (493), Expect = 3e-50
Identities = 161/542 (29%), Positives = 254/542 (46%), Gaps = 37/542 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+ A KAG AYVP++ P R ++L+ A P L I + D +F
Sbjct: 497 SMVAMYAVVKAGGAYVPLDSDHPAERTAYVLESARP-LCILTVARDGLVFPADQ---DVL 552
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E A + + A D E A L + A V+YTSGSTG PKGV +S++++ N++ W
Sbjct: 553 EIDALDLSGAPAGPIRDDERAADLRPANPAYVIYTSGSTGRPKGVAVSHASVLNQVTWIA 612
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
+ D+ ++ + KT TF SV E++ L G L+I + E RDP L ++ V
Sbjct: 613 SRYGL-DANDVVLQKTPTTFDVSVWELFAALASGSRLVIAAPEGHRDPAYLADVIAREKV 671
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ + S+L L L++ + +GE +A+ F ++ G L N YG
Sbjct: 672 TATSFVPSMLSVFVAEADREQLVSLRVVLVAGEAFPPAVAATFRAK--SDAG--LHNLYG 727
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T + G + TIPIG P+ N Y+LD L P GE+++AGA
Sbjct: 728 PTEF----TVHATAGEVDRETLHTIPIGTPVWNTEAYVLDGHLRPAPIGSAGELYLAGAQ 783
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGH 373
+A GY G A RF NP RLYRTGD V G++ Y GRTD QVK+RG
Sbjct: 784 VARGYEGRPELTAERFVANPFGAAG--TRLYRTGDLVKWRVDGSIEYLGRTDFQVKVRGL 841
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E A++ P V + V + + G ++G+V +PG+ + + + A+
Sbjct: 842 RIELGEIEAAMSSYPHVAQSVAVVHDSSLGQ-RLVGYVVPEPGSAVDVEDLTVHVGRAVP 900
Query: 434 HYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P V+ + +P+ +GK+DR+ L E + S
Sbjct: 901 SYMVPDAVVVIAEMPVGASGKLDRKAL------------PEPTFAAESSEYVAPRSTMEE 948
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLG 552
VLG +S+ F+ LGG+S+ SI +++ ++ G D T+
Sbjct: 949 SIAGLFAEVLGLP---RVSVGDSFFALGGDSIVSIQLVSRAKEAGVLFTARDVFERKTVA 1005
Query: 553 EV 554
+
Sbjct: 1006 SL 1007
Score = 201 bits (490), Expect = 7e-50
Identities = 140/453 (30%), Positives = 225/453 (49%), Gaps = 21/453 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVP--FAS 77
+++LLA KAG Y+P + ++P R+ +L DA P +VI A + ++G+P
Sbjct: 5502 VVSLLAVVKAGGGYLPTDVTYPADRLEFMLTDARP-VVILTSIAHAAGLPDTGIPTVLLD 5560
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+E + A + E A L ++++A V+YTSGSTG PKGV +++SA+
Sbjct: 5561 ADETLIDLADLDAGPVEERERHAALRANNLAYVIYTSGSTGRPKGVMVTHSAVVQLFDRT 5620
Query: 138 FRTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
F F + DS+ VW + F SV E+WG LL+G L+++ T+R P + +
Sbjct: 5621 FGEFGFDDSD---VWTLFHSYAFDFSVWELWGALLYGGRLVVVDYLTSRSPDEFRALLSR 5677
Query: 196 VLVPTLLRSILMYLALGPASRPLRR-----LKLWVCSGETLSKELASEFFKYFGNEDGYK 250
V L ++ + L A R L L+ + GE L S+++ E +
Sbjct: 5678 ERVTVLSQTPSAFYQLSAADRALETPDDLALRYVIFGGEALDLGQLSKWYDRHP-ETAPR 5736
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE VT+ L+ ++ +G P+D +++LD L P GE+
Sbjct: 5737 LVNMYGITETTVHVTHLALDRKFAESASASV-VGEPIDGLRVHVLDSRLRPVPTGVSGEM 5795
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQ 367
+++G L GY+ + RF NP RLYR+GD +L Y GR+D+Q
Sbjct: 5796 YISGGQLTRGYLQRPDLTSTRFVANPFGATGG--RLYRSGDVARWNSAGLLEYLGRSDSQ 5853
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
+++RG R++L E+E AL + PGV V + ++G+V + GA I+
Sbjct: 5854 IQLRGFRIELGEIESALLRAPGVAASVAVVLRDAEVGDRLVGYVVPESGAILVPTEIKDF 5913
Query: 428 LRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
LT YM+P V+ V ++P+ VNGK+DR+ L
Sbjct: 5914 ASGFLTSYMVPDVVMVLGAMPITVNGKLDRKAL 5946
Score = 153 bits (371), Expect = 2e-35
Identities = 151/567 (26%), Positives = 257/567 (45%), Gaps = 54/567 (9%)
Query: 19 TIMALLATW---KAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPF 75
++ +++ATW KAG +VP++P +P RI H++ D+ L + + ++ S V +
Sbjct: 2064 SLHSVIATWAVAKAGGTFVPVDPRYPSERIAHMVADSGAILGLTVAAQRDTL--PSDVEW 2121
Query: 76 ASFEELAQEA--TSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
+ + +A SAD D+E A + + A ++YTSG+TG+PKGV ++++ + N
Sbjct: 2122 LALDSSECDALCAPKSADPVTDSERTASVQLEHPAYMIYTSGTTGLPKGVVVTHTGLANF 2181
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
Q + S S + + +F SV E+ G A +I++ ++L N
Sbjct: 2182 SAEQRTHYGVSPSARTLHFASP-SFDASVLELLLAFGCG-ATMIVAPADLYGGEELRNFL 2239
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V + ++ PA L RL++ V GE EL + G ++ N
Sbjct: 2240 ADNEVTHAFVTPAALASVEPAG--LDRLEVVVVGGEACPPELVERW------APGRRMYN 2291
Query: 254 FYGSTE--VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
YG TE +M +V+ ++ GS + IG P+ +Y+LDE L P GE++
Sbjct: 2292 GYGPTEATIMSNVSNLLVPGS-------RVEIGGPVCGVTVYVLDELLRPVPVGVAGELY 2344
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG-------AVLYAG 362
+AG LA GY G A RF NP R+YRTGD V V Y G
Sbjct: 2345 IAGPGLARGYHDRLGLTAERFVANPFGDSGS--RMYRTGDVVRFVVDHGHRSGYGVEYVG 2402
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R+D QVK+RG R++L E++ L + P ++ L + G+ ++ +V GA
Sbjct: 2403 RSDFQVKVRGFRIELGEIDAVLVKHPDLEFAATLGTSMPSGSTALVSYVLPTAGASVDVA 2462
Query: 423 HIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCS 481
+ + L +M+P V+ ++ IPL GK+DR+ L + + + E +
Sbjct: 2463 EVTHFVGDMLPAHMVPSSVVVLDEIPLTTAGKLDRKALPEPDFDALQGEMIEPRTPTE-- 2520
Query: 482 XXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYV 540
+ VLG A +S+ F++LGGNSL + + +L G +
Sbjct: 2521 ----------ELVAGVLADVLGLA---KISVAESFFDLGGNSLVATKAVARLNAAAGTRL 2567
Query: 541 EISDFLGASTLGEVLSKMSTDPNGGAD 567
+ + A T+ + K++ G+D
Sbjct: 2568 GVRELFDAPTVERLAVKVAEQAGTGSD 2594
Score = 151 bits (366), Expect = 7e-35
Identities = 131/447 (29%), Positives = 208/447 (46%), Gaps = 25/447 (5%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+I+ + + KAG AY+P++P P RI +L D+ L + + VP+
Sbjct: 6577 SILGIWSIAKAGGAYLPVDPKLPFERIGEMLSDSGAVLGLTVARHHDDL--PGTVPWIVL 6634
Query: 79 EELA--QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+E A +E + SA DA+ LT D A ++YTSGSTG PKGV +++ + N L
Sbjct: 6635 DETAAAEEIGARSAGAVEDADLRRALTVDHPAYLIYTSGSTGKPKGVVVTHRGLAN-LTR 6693
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+ R + + + +F SV E+ G A L++S +L ++ R
Sbjct: 6694 EVREHYVVSPDSRFLHVASPSFDTSVGEMLAAFSAG-ATLVISPADVYGGDELADLIRRE 6752
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V ++ + + + P L + V G+T + EL + + G ++ N YG
Sbjct: 6753 RVNNVVMTPTALMTVDPDG--LDTVTSVVVGGDTCTPELVARW------APGREMRNAYG 6804
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE VT ++ + + IG PL +LD L P + PGE+++ G +
Sbjct: 6805 PTETTVIVTI-----TEPMVAGERVTIGSPLRGVESLILDSRLRPVPEGVPGELYICGPS 6859
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG-AVLYAGRTDAQVKIRGH 373
+ GY A RF NP +P R+YRTGD G V Y GR+D QVK+RG
Sbjct: 6860 VTRGYHNRPSVTAERFVANPFG-EPG-ARMYRTGDVVRWADGHRVEYVGRSDFQVKVRGF 6917
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
RV+L E++ ALA P V+ V + G ++ +V GA + ++ + L
Sbjct: 6918 RVELGEIDAALAAQPNVEFAVTVGRENPAGLTTLVSYVLPADGATVDPESLKSVVGETLP 6977
Query: 434 HYMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM+P VI ++ +PL GK+DR L
Sbjct: 6978 PYMVPSVVILLDEVPLTGIGKLDRARL 7004
Score = 147 bits (355), Expect = 2e-33
Identities = 124/451 (27%), Positives = 207/451 (45%), Gaps = 27/451 (5%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+I+++ A K GAA+VP++PS+P RI H++ D+ + + + +
Sbjct: 8696 SILSIWAVAKTGAAFVPVDPSYPFERILHMVTDSRVEVGLTTGAHVGELPDTVRWLVLGE 8755
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+E+ + S S++ DA+ + P D A V+YTSGSTG+PKGV ++++ + N Q
Sbjct: 8756 DEMDGDCASVSSEAVTDADRIRPTRVDDAAYVIYTSGSTGLPKGVVVTHTGLANVTTEQV 8815
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ + + + +F SV E+ + ++I S +L + + V
Sbjct: 8816 ERLRLTPQSRVLHFASP-SFDASVFELLHAVAAASTMVIASG-VVYGGDELARLLKKQKV 8873
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + PA L +++ +GE EL ++ G ++ N YG +
Sbjct: 8874 THAFITPAALTTVDPAG--LDGIEVLSVAGEACPPELMQKW------APGRRMFNLYGPS 8925
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T S+ + + IG P + +LD L+P GE++VAG ++A
Sbjct: 8926 EATIWST-----SSNPMKADQPVTIGGPTRGVDVVVLDSRLTPVPVGVAGELYVAGPSVA 8980
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGA-----VL-YAGRTDAQVKI 370
GY A RF NP E RLYRTGD V VL Y GR+D QVK+
Sbjct: 8981 RGYHNRFALTAERFVANPFGGPGE--RLYRTGDVVRWVHDGETGDLVLDYVGRSDFQVKV 9038
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLD-RGNPEILGFVTTKPGARTSAQHIEGKLR 429
RG R++L E++ L P VD V L + + G ++ +V GA + +
Sbjct: 9039 RGFRIELGEIDAELGSHPSVDFAVTLGHHRELTGQTVLVSYVMPAAGASIDVAELSAFVS 9098
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P ++ ++S+PL GK+DR+ L
Sbjct: 9099 ETLPGYMVPSSIMAIDSVPLTPAGKLDRKAL 9129
Score = 146 bits (353), Expect = 3e-33
Identities = 154/562 (27%), Positives = 242/562 (43%), Gaps = 54/562 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESG------- 72
++ ++A WK GAAY P + + RI +++D+ V+ +S G
Sbjct: 3255 VIGMIAAWKLGAAYSPFDQDWGLDRIVGLIEDSGTRAVVVTNSWSGLTEAPLGNAVLDAA 3314
Query: 73 --VPFA-SFEELAQEATSHSADEP-MDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYS 128
V A + E LA S A +P DAE S +A V+ TSGSTG PK +
Sbjct: 3315 IVVDDADTIERLAAHDVSDFAHDPWSDAE-----ASSRLAYVISTSGSTGRPKPTMVPMI 3369
Query: 129 AICNRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK 188
+ N W +++ + V + L F + IW + +G + + + DP
Sbjct: 3370 GVSNTYQWYRHALDFTEGTGVLVANSPL-FDQTQKNIWVSVAYGGVMHL--AQPGFDPLP 3426
Query: 189 LVNIERL--VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNE 246
++ V + + S L+ L +L + V GE L S G +
Sbjct: 3427 ILRQIGTGDVQIANMAPSAFEVLSDLDTEGVLGKLDIVVVGGEQLRPAACSAL---IGTQ 3483
Query: 247 DGYKLANFYGSTEVMG-DVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDS 305
+L N YG TE D +Y V S + +P +P G + ++LD + P
Sbjct: 3484 T--RLINTYGPTEASATDSSYEVDLSSADAEQWP-VPFGAAFEGVEYHVLDGRMRPVPPG 3540
Query: 306 EPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAG 362
GE+++ G LA GY G G A+RF NP RLYRTGD G +++ G
Sbjct: 3541 VTGELYIGGIVLARGYGGMTGITASRFVANPFGNAG--TRLYRTGDLVRERDHGQLVFVG 3598
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R+D QVKIRG R++L E+E AL V + VV+ + ++G P ++ +VT G
Sbjct: 3599 RSDFQVKIRGLRIELGEIESALTANSDVLQSVVVVHESEQG-PRLVSYVTAAAGVELDID 3657
Query: 423 HIEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCS 481
I L AL +M+P + V + +PL N KVDR+ L + T+ + ++
Sbjct: 3658 AILDDLHRALPSHMIPDTVMVLDEMPLNANLKVDRKALPEPVFATSTVEFVAPRTPLE-- 3715
Query: 482 XXXXXXXXXXXXXXXTVGAVLGRAARGT-LSLRSGFYELGGNSLNSIYTITKLRD-RGYY 539
V + G T +S+ F++LGGNSL++ ++ G
Sbjct: 3716 --------------EVVAGIFGDVVSATRVSVDESFFDLGGNSLSATRVAARVTSATGTE 3761
Query: 540 VEISDFLGASTLGEVLSKMSTD 561
V I D A T+ L+K+ D
Sbjct: 3762 VGIRDLFEAPTVA-TLAKLVED 3782
Score = 143 bits (346), Expect = 2e-32
Identities = 125/454 (27%), Positives = 206/454 (45%), Gaps = 35/454 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+I + A K+G AYVP++P +P RI H++ D+ SL + S + +
Sbjct: 4327 SIAGIWAVAKSGGAYVPIDPGYPDERIAHMVTDSGVSLGLSVSSEVGRLPADVDWLVLDS 4386
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E+ A +S + E +T + A V+YTSG+TG PKGV +++ + N Q
Sbjct: 4387 EDFENAAAQYSTAPVAEVERRTAVTPANSAYVIYTSGTTGQPKGVVVTHRGLANFAAEQR 4446
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ--KLVNIERLV 196
+ + + + +F SV E+ + G ++I + P+ K + R+
Sbjct: 4447 ERYRVTTDSRTLHFASP-SFDASVLELLLAVGAGATMVIAPTDVYGGPEFAKFLREHRVT 4505
Query: 197 ---LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ P+ L S+ P+ L + V GE + ELA+ + G L N
Sbjct: 4506 HGFVTPSALASV------DPSG--LDDFQFVVAGGEAVPAELAARW------APGRSLFN 4551
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T + SD + + IG P+ + +LD+ L P G+++++
Sbjct: 4552 GYGPTE-----TTIMTNISDPMAADGPVTIGGPIRGTSALVLDDRLRPVPVGIAGDLYLS 4606
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGA-----VLYAGRTDA 366
G LA GY A RF NP+ + R+YRTGD K A V Y GR+D
Sbjct: 4607 GLGLARGYHRRTPLTAGRFVANPYGEPGD--RMYRTGDVVRWTKDADGALTVDYVGRSDQ 4664
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVK+RG R++L E++ LA+ P VD G+ ++ +V PG +
Sbjct: 4665 QVKVRGFRIELGEIDAVLAKHPAVDFATTSVLPGPSGDSVLVSYVLPVPGVEVDVPRMLD 4724
Query: 427 KLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
+ + YM+P ++ +++IPL GK+DR+ L
Sbjct: 4725 FVGEFVPTYMVPSTIVTLDAIPLTPVGKLDRRAL 4758
>UniRef50_Q87WM8 Cluster: Non-ribosomal peptide synthetase, initiating
component; n=1; Pseudomonas syringae pv. tomato|Rep:
Non-ribosomal peptide synthetase, initiating component -
Pseudomonas syringae pv. tomato
Length = 1753
Score = 231 bits (564), Expect = 7e-59
Identities = 153/447 (34%), Positives = 237/447 (53%), Gaps = 25/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ L+A KAG AYVP++P +P R+ ++L D++P +++ +S + E VP E
Sbjct: 1216 VITLMAILKAGGAYVPLDPGYPTERLAYMLDDSKPDVLVSQESVRDCL-PEHSVPTLWLE 1274
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
QE S+ +T DS+A +YTSGSTG PKGV ++ A+ NRL W
Sbjct: 1275 TEEQEIAGCSSHNLTIGDT------DSLAYCIYTSGSTGRPKGVMNAHGAVVNRLQWMQE 1328
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ S+ + + + KT +F SV E + PL+ G L+I E +DP L N+ ++ V
Sbjct: 1329 QYALSNQDRV-LQKTPFSFDVSVWEFFWPLIQGARLVICKPEGHKDPSYLWNLIGQQGVT 1387
Query: 198 VPTLLRSILM-YLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ S+L +L GPA +P L+ SGE L +A+EF + + + +L N YG
Sbjct: 1388 TAHFVPSMLQAFLKTGPA-QPADSLRHVFSSGEALPVAVANEFLERYRHT---RLHNLYG 1443
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DV+Y+ + + +P +PIGRP+ N +Y+LDE L P G++++AG
Sbjct: 1444 PTEAAVDVSYWECQPDYR---HPLVPIGRPVANTRLYILDETLQPAPIGVIGDLYIAGVQ 1500
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
LA GY G A RF +P+ R+Y TGD G L G + Y GR D Q+KIRG
Sbjct: 1501 LARGYFGRPDLTAERFIPDPNDNHG--GRMYLTGDRGRYLPSGDIQYLGRIDHQIKIRGF 1558
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++ E+E AL Q P V + VV+ G ++ ++ + +AQ + ++ L
Sbjct: 1559 RIEPGEIENALLQCPTVREAVVVPRDDAFGGQYLVAYIASSVSEPDAAQ-LRKQIGKILP 1617
Query: 434 HYMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM P + + ++PL NGK+DRQ L
Sbjct: 1618 DYMQPSFYVVLAALPLSANGKIDRQAL 1644
Score = 38.7 bits (86), Expect = 0.59
Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Query: 21 MALLATWKAGAAYVP-MEPSFPQG--RITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
+A A AG VP + P+ + R+ I +D++P+L + D+ + + V +
Sbjct: 83 IAFYACIYAGVIAVPALSPANAKTLPRLHLIAQDSQPALALTMDAVLTGL--QRIVTDDN 140
Query: 78 FEELAQEATSHSADEPMDAET---LAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
L + T S++ +DA P + I + YTSGSTG PKGV +S++ + +
Sbjct: 141 TPNLLTDITWLSSNLLVDASADWQCPPTVASDIVFLQYTSGSTGAPKGVMVSHANLLANV 200
Query: 135 WWQFRTFPYSDSEEICVWKTA 155
+T+ + + W A
Sbjct: 201 ELSKQTYRIREQDVFVSWLPA 221
>UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|Rep:
Amino acid adenylation - Pseudomonas syringae pv.
syringae (strain B728a)
Length = 13537
Score = 231 bits (564), Expect = 7e-59
Identities = 152/450 (33%), Positives = 232/450 (51%), Gaps = 24/450 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL K+GA YVP++P++P R+ + L D+ P ++ S ++ + VP S +
Sbjct: 3839 IIGLLGILKSGAGYVPLDPAYPLERLAYTLGDSTPVALLSQQSVQQAL-PVTEVPIISLD 3897
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + DE + ++ LT+ S+A V+YTSGSTG+PKGV + + + RL+ +
Sbjct: 3898 DADLQ------DESVCNPEVSGLTAASLAYVIYTSGSTGLPKGVMVEHRNVA-RLFSATQ 3950
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VNIE 193
+ +++ + F SV EIWG LLHG LLI+ + +R P+ +
Sbjct: 3951 DWFGFGEQDVWALFHSFAFDFSVWEIWGALLHGGRLLIVPQLVSRSPRDFHDLLCSAGVT 4010
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L P+ R ++ + LR++ + GE L + ++ N G +L N
Sbjct: 4011 VLNQTPSAFRQLIAAQGENEQAHSLRQV---IFGGEALETAMLKPWYARQANA-GTQLVN 4066
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTYY L+ D L + PIGR + + +Y+LD P GE++V
Sbjct: 4067 MYGITETTVHVTYYPLQPEDAQRLGAS-PIGRRIPDLQLYVLDARGEPVPVGVVGELYVG 4125
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA +A GY+ A RF DNP T P RLYRTGD G L G++ Y GR D QVKI
Sbjct: 4126 GAGVARGYLNREALTAERFIDNPFNTAPG-ARLYRTGDLGRWLADGSLEYLGRNDEQVKI 4184
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L GV +VL + G+ ++ +V GA A H+ +LR
Sbjct: 4185 RGFRIELGEIEAQLVACDGVQDAMVLVREDEPGDKRLVAYVIGTAGAELDATHLREQLRL 4244
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+L YM+P + +E+ PL NGK+DR+ L
Sbjct: 4245 SLAEYMLPSAFVSLEAFPLTANGKLDRKAL 4274
Score = 221 bits (539), Expect = 8e-56
Identities = 150/451 (33%), Positives = 233/451 (51%), Gaps = 27/451 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL K+GA YVP++P++P R+ + L D+ P ++ S ++ S VP +
Sbjct: 8180 IIGLLGILKSGAGYVPLDPAYPLERLAYTLGDSAPVALLSQRSVQGTL-PVSQVPVICLD 8238
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ Q+ S P P+T ++A V+YTSGSTG PKGV + + + RL+
Sbjct: 8239 DDLQD---ESVCNPQ-----VPVTPGNLAYVIYTSGSTGKPKGVMIEHRNVA-RLFSATE 8289
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
+ + +++ + F SV EIWG LLHG LLI+ + +R P+ N +
Sbjct: 8290 EWFGFNQQDVWALFHSFAFDFSVWEIWGALLHGGRLLIVPQLVSRSPEDFYNLLCSAGVT 8349
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L P+ R ++ A + LR++ + GE L + ++ N G +L N
Sbjct: 8350 VLNQTPSAFRQLIAAQAENTQAHSLRQV---IFGGEALETAMLKPWYARQANA-GTQLVN 8405
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTYY L+ D L + PIGR + + +Y+LD P GE++V
Sbjct: 8406 MYGITETTVHVTYYPLQPEDAQRLGAS-PIGRRIPDLQLYVLDARGEPVPVGVVGELYVG 8464
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA +A GY+ A RF DNP + + R+YRTGD G L G++ Y GR D QVKI
Sbjct: 8465 GAGVARGYLNREALTAERFLDNPFSHTAD-ARMYRTGDLGRWLADGSLEYLGRNDEQVKI 8523
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT-KPGARTSAQHIEGKLR 429
RG R++L E+E LA+ P V VVLC G+ ++ +VT +P + + + L+
Sbjct: 8524 RGFRIELGEIEARLAEYPDVRDAVVLCREDVPGDKRLVAYVTAQQPESLLDIESLREHLQ 8583
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
AL +M+P ++++ +PL NGK+DR+ L
Sbjct: 8584 GALPEHMVPAAYVQLDELPLTANGKLDRKAL 8614
Score = 212 bits (517), Expect = 4e-53
Identities = 151/452 (33%), Positives = 236/452 (52%), Gaps = 26/452 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL KAG AYVP++P P R T++L+D+ P V+ ++ S +P +
Sbjct: 6014 VVALLGILKAGGAYVPIDPDLPSARQTYMLEDSSPQAVLTTRDLSDNL-PASDLPVLVLD 6072
Query: 80 ---ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ AQ A S + DA+ L L + +A VLYTSGSTG PKGV + + NRL W
Sbjct: 6073 GRDDRAQLARQPSVNP--DAKALG-LQPNHLAYVLYTSGSTGTPKGVMNEHLGVVNRLLW 6129
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ER 194
+ + + + + KT F SV E + PLL G L++ +DP L + +
Sbjct: 6130 ARDAYQVNSQDRV-LQKTPFGFDVSVWEFFLPLLTGAELVMARPGGHQDPDYLAQVMSDA 6188
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ + + S+L ++R +L+ +CSGE L + L F ++ G +L N
Sbjct: 6189 GITLLHFVPSMLDVFLEHRSTRDFPQLRRVLCSGEALPRALQRRFEQHL---KGVELHNL 6245
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDE--ELSPTRDSEPGEVWV 312
YG TE DVT + +D D ++PIGRP+ N +++LD +L P GE+ +
Sbjct: 6246 YGPTEAAIDVTAWECRPTDPGD---SVPIGRPIANIQMHVLDALGQLQPL--GVAGELHI 6300
Query: 313 AGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
G +A GY+ A RF +P ++ P+ RLY+TGD G L GA+ Y GR D QVK
Sbjct: 6301 GGIGVARGYLNQPDLSAERFIADPFSSDPQ-ARLYKTGDVGRWLANGALEYLGRNDFQVK 6359
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGKL 428
IRG R+++ E+E ALA+ P V + VV G+ ++ + T + + + G L
Sbjct: 6360 IRGLRIEIGEIEAALAKHPAVHEAVVTAREDIPGDKRLVAYYTQSAEHTAVDIETLRGHL 6419
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ L YM+P + + +E++PL NGK+DR+ L
Sbjct: 6420 QQQLPEYMVPAIYVLLEAMPLTSNGKLDRKAL 6451
Score = 208 bits (508), Expect = 4e-52
Identities = 154/474 (32%), Positives = 235/474 (49%), Gaps = 31/474 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAGA YVP++P++P RI + L+D+ P V+ D +A ++ P
Sbjct: 4926 IVGLLGVLKAGAGYVPIDPAYPAERIAYQLQDSAPMAVLAD-AAGLALLGSFDGPRVDLH 4984
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A +A +P L L+ +A V+YTSGSTG+PKGV + + + RL+ +
Sbjct: 4985 SPALQA------QPGHNPQLTGLSPRHLAYVIYTSGSTGLPKGVMVEHRNVA-RLFSATQ 5037
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK----LVNIERL 195
++ + +++ + F SV EIWG LLHG LLI+ + +R PQ L N
Sbjct: 5038 SWFGFNEQDVWALFHSFAFDFSVWEIWGALLHGGRLLIVPQLVSRSPQDCYALLCNAGVT 5097
Query: 196 VL--VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VL P+ R +L LR++ + GE L + ++ N G +L N
Sbjct: 5098 VLNQTPSAFRQLLNAQGESDQRHSLRQV---IFGGEALDTGMLKPWYARVINA-GTQLVN 5153
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTY+ L +D PIG + + +Y+LD P GE++V
Sbjct: 5154 MYGITETTVHVTYHPLVAADA-QRSGVSPIGVRIPDLQLYVLDARREPVPVGVVGELYVG 5212
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA +A GY+ A RF NP + +P+ RLYRTGD G + G++ Y GR D QVKI
Sbjct: 5213 GAGVARGYLNREALTAERFLANPFSKEPQ-ARLYRTGDLGRWMADGSLDYLGRNDDQVKI 5271
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E++ LA V + +VL G+ ++ +V PG A + +L
Sbjct: 5272 RGFRIELGEIQAVLAACNTVREALVLVREDQPGDKRLVAYVIAAPGHEIVAADLRAQLLL 5331
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL-------LKMYENTNNNDDAEVAV 476
+L +M+P + ++S PL NGK+D++ L L M E D E+A+
Sbjct: 5332 SLADHMVPSAFVALDSFPLTANGKLDQKALPAPDAQALAMREYAPPEGDVEIAI 5385
Score = 203 bits (496), Expect = 1e-50
Identities = 159/538 (29%), Positives = 259/538 (48%), Gaps = 44/538 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG YVP++P++P RI ++L+D+ P+ V+ +A + + VP + +
Sbjct: 7105 VVGLLAILKAGGGYVPLDPAYPAERIAYMLQDSAPAAVLAQ-TATQGLLADVSVPVINLD 7163
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
S+ DE + + LTS +A ++YTSGSTG+PKGV + + N L W
Sbjct: 7164 ------LSNWQDESVQNPQVPGLTSAHLAYLIYTSGSTGLPKGVMIEHRNTVNFLTWAHT 7217
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER-LVLV 198
F S E+ ++ T+L F +V E + PL G ++ E ++ +L + E + L+
Sbjct: 7218 AFDGSALEK-TLFSTSLNFDLAVYECFAPLTSGGSI-----EVVKNVLELQHGEHDIGLI 7271
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
T+ ++ L + R + + + +GE L + L + F+ G + +L N YG +
Sbjct: 7272 NTVPSALKALLDVDGLPRSVHTVNV---AGEALKRSLVEDLFERTGVQ---RLCNLYGPS 7325
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E TY D+ + IG+P+ N YLLDE+ P GE+++ GA +A
Sbjct: 7326 ET---TTYSSWVAMDREQGF-AAHIGKPVGNTQFYLLDEQQQPVPLGVSGEIYIGGAGVA 7381
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +P + P R+YRTGD G L G + Y GR D QVKIRG R+
Sbjct: 7382 RGYLNRDDLTAERFLKDPFSQNPA-ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRI 7440
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIEGKLRSALTH 434
+L E++ LA+ P V + VV G+ ++ + T G A + G L+ L
Sbjct: 7441 ELGEIDARLAKHPAVHEAVVTAREDVPGDKRLVAYYTLSAGHASVDIDSLRGWLQEQLPA 7500
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P + ++++PL NGK+DR+ L DA ++ +
Sbjct: 7501 YMIPVAYVLLDALPLTPNGKLDRKAL------PAPEADALISRGYEAPQGETETQIAAIW 7554
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
A +GR F+ELGG+SL ++ I ++R G ++ G TL
Sbjct: 7555 QDLLGVAQVGR--------HDNFFELGGHSLLAVSLIGRMRQSGLSSDVRVLFGQPTL 7604
Score = 203 bits (495), Expect = 2e-50
Identities = 158/549 (28%), Positives = 258/549 (46%), Gaps = 44/549 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG YVP++P++P RI ++L+D+ P+ V+ +A + + VP + +
Sbjct: 1688 VVGLLAILKAGGGYVPLDPAYPAERIAYMLQDSAPAAVL-AQTATQGLLADVSVPVINLD 1746
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
S D+ + + LTS +A ++YTSGSTG+PKGV + + N L W
Sbjct: 1747 ------LSDWQDQSVQNPQVPGLTSAHLAYLIYTSGSTGLPKGVMIEHRNTVNFLTWAHS 1800
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F S E+ ++ T+L F +V E + PL G ++ I+ + +I + VP
Sbjct: 1801 AFDASALEK-TLFSTSLNFDLAVYECFAPLTSGGSIEIV-KNVLELQHGEHDIGLINTVP 1858
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ L+++L L + + +GE L + L + F+ G + +L N YG +E
Sbjct: 1859 SALKALLEVNGLPESVHTVN------VAGEALKRSLVEDLFESTGVQ---RLCNLYGPSE 1909
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
TY D+ D + IG+P+ N YLLDE+ P GE+++ GA +A
Sbjct: 1910 T---TTYSSWVAMDREDGF-AAHIGKPVGNTRFYLLDEQQQPVPLGVAGEIYIGGAGVAR 1965
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ A RF +P + QP R+YRTGD G L G + Y GR D QVKIRG R++
Sbjct: 1966 GYLNRDDLTAERFLLDPFSQQPA-ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIE 2024
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIEGKLRSALTHY 435
L E++ LA+ P V + VV G+ ++ + T G ++ L+ L Y
Sbjct: 2025 LGEIDARLAKHPAVHEAVVTAREDIPGDKRLVAYYTLVSGHTSVDIDNLRSHLQEKLPEY 2084
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P + + +E++PL NGK+DR+ L A D++
Sbjct: 2085 MVPAIYVLLEAMPLTPNGKLDRKAL--------------PAPDVEALSSRGYEAPQGETE 2130
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEV 554
+ F+ELGG+SL ++ I ++R G ++ TL +
Sbjct: 2131 TQLAAIWQDLLGVARIGRHDNFFELGGHSLLAVSLIGRMRQLGLSADVRVLFSQPTLAAL 2190
Query: 555 LSKM--STD 561
+ + STD
Sbjct: 2191 AAAVGGSTD 2199
Score = 196 bits (478), Expect = 2e-48
Identities = 138/445 (31%), Positives = 224/445 (50%), Gaps = 28/445 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG YVP++P++P RI ++L+D+ P+ V+ +A + + P + +
Sbjct: 9265 VVGLLAVLKAGGGYVPLDPAYPAERIAYMLQDSAPAAVL-AQTATQGLLADVSAPVINLD 9323
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
S D+ + + LTS +A ++YTSGSTG+PKGV + + N L W
Sbjct: 9324 ------LSDWQDQSVQNPQVPGLTSAHLAYLIYTSGSTGLPKGVMIEHRNTVNFLTWAHT 9377
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F S E+ ++ T+L F +V E + PL G ++ ++ + +I + VP
Sbjct: 9378 AFDGSALEK-TLFSTSLNFDLAVYECFAPLTSGGSIEVV-KNVLELQHGEHDIGLINTVP 9435
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ L+++L L + + +GE L + L F+ G + +L N YG +E
Sbjct: 9436 SALKALLEVNGLPESVHTVN------VAGEALKRSLVENLFEKTGVQ---RLCNLYGPSE 9486
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
TY D+ + IG+P+ N YLLDE+ P GE+++ GA +A
Sbjct: 9487 T---TTYSSWVAMDREHGF-AAHIGKPVGNTQFYLLDEQQQPVPLGVAGEIYIGGAGVAR 9542
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ A RF +P + QP R+YRTGD G L G + Y GR D QVKIRG R++
Sbjct: 9543 GYLNRDDLTAERFVKDPFSPQPA-ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIE 9601
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIEGKLRSALTHY 435
L E++ LA+ P + + VV G+ ++ + T G A + G L+ L Y
Sbjct: 9602 LGEIDARLAKHPAIHEAVVAAREDVPGDKRLVAYYTLSAGHASVDIDSLRGWLQEQLPAY 9661
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGL 459
M+P + ++++PL NGK+DR+ L
Sbjct: 9662 MIPVAYVLLDALPLTPNGKLDRKAL 9686
Score = 196 bits (477), Expect = 2e-48
Identities = 140/449 (31%), Positives = 228/449 (50%), Gaps = 32/449 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG YVP++P++P RI ++L+D+ P+ V+ SA ++ + VP + +
Sbjct: 2761 VVGLLAILKAGGGYVPLDPAYPAERIAYMLQDSAPAAVLAQ-SATEALLADVSVPVINLD 2819
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ D+ + + LTS +A ++YTSGSTG+PKGV + + N L W
Sbjct: 2820 ------LGNWQDQSVQNPQVPGLTSAHLAYLIYTSGSTGLPKGVMIEHRNTVNFLTWAHS 2873
Query: 140 TFPYSDSE---EICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
F + E ++ T+L F +V E + PL G ++ E ++ +L N E +
Sbjct: 2874 AFDAGTATSALEKTLFSTSLNFDLAVYECFAPLTSGGSI-----EVVKNVLELQNGEHDI 2928
Query: 197 -LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
L+ T+ ++ L + + + + +GE L + L F+ G +L N Y
Sbjct: 2929 GLINTVPSALKALLEVDGLPTSVHTVNV---AGEALKRSLVESLFEKTGVR---RLCNLY 2982
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G +E TY D+ D + IG+P+ N YLLDE+ P GE+++ GA
Sbjct: 2983 GPSET---TTYSSWVAMDREDGFAA-HIGKPVGNTQFYLLDEQQQPVPLGVAGEIYIGGA 3038
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
+A GY+ A RF +P + QP R+YRTGD G L G + Y GR D QVKIRG
Sbjct: 3039 GVARGYLNRDELTAERFLTDPFSQQPA-ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRG 3097
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIEGKLRSA 431
R++L E++ LA+ P V + VV G+ ++ + T G A + + G L+
Sbjct: 3098 FRIELGEIDARLAKHPAVHEAVVTAREDIPGDKRLVAYYTLSAGHASVDSDSLRGWLQEQ 3157
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L +M+P + ++++PL NGK+DR+ L
Sbjct: 3158 LPAHMIPAAYVLLDAMPLTPNGKLDRKAL 3186
Score = 174 bits (423), Expect = 9e-42
Identities = 131/450 (29%), Positives = 212/450 (47%), Gaps = 19/450 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAGAAYVP++P++P R+ +++ D++P+ ++ + S +P +
Sbjct: 10314 IVGLLGVLKAGAAYVPLDPAYPAERLAYMINDSQPAALLTQRGLQERLPALS-MPLVLLD 10372
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + D P+ + L ++A V+YTSGSTG PKGV + + + N R
Sbjct: 10373 DEHCQGFTECDDNPV----VPTLGVRNLAYVIYTSGSTGNPKGVMIEHRGLVNYSVDAAR 10428
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALL----ILSRETTRDPQKLVNIERL 195
F S S+ + T L F SV EI+ LL G L I E T + + L
Sbjct: 10429 LFGLSQSDTVLQQNT-LNFDLSVEEIFPALLAGATLAPSREIFGSEGTENHGIYPTVLHL 10487
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ A + L ++L +G+ LS + + + +L N Y
Sbjct: 10488 TAAHWHTLVAEWHNQPQAAEQRLAEVRLINVTGDALSAQKLKLWDEV--RPAHTRLINTY 10545
Query: 256 GSTEVMGDVT--YYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
G TE T Y + + + IG+P+ N IYLLDE P GE+++
Sbjct: 10546 GPTEATVSCTAAYVSHDAAAGSEGSGNATIGKPMANTRIYLLDEHQQPVPYGVAGEIFIG 10605
Query: 314 GANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ A RF +P + P+ R+Y+TGD + G + Y GR D QVK+
Sbjct: 10606 GDGVARGYLNLEEVNAERFLADPFSNSPD-ARMYKTGDLARYMADGRIEYLGRNDFQVKV 10664
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L GV + VV+ + G ++ +V +P A A + +L
Sbjct: 10665 RGFRIELGEIEARLGNCKGVKEAVVIAREDNPGEKRLVAYVIAQPQANLDAASLRAELAP 10724
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++++PL N K+DR+ L
Sbjct: 10725 QLAEYMLPSAFVLLDALPLTPNRKLDRKAL 10754
Score = 171 bits (415), Expect = 8e-41
Identities = 129/450 (28%), Positives = 211/450 (46%), Gaps = 19/450 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGAAYVP++P++P R+ +++ D++P+ ++ + +P +
Sbjct: 11382 MIGLLGVLKAGAAYVPLDPAYPAERLAYMITDSQPAALLTQRDLQKRL-PTLTLPLVLLD 11440
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + D P+ + L ++A V+YTSGSTG PKGV + + + N R
Sbjct: 11441 DDQRNTFTERDDNPV----VEALGVRNLAYVIYTSGSTGNPKGVMIEHRGLVNYSVDAAR 11496
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALL----ILSRETTRDPQKLVNIERL 195
F S S+ + T L F SV EI+ LL G L I E T + + L
Sbjct: 11497 LFALSQSDTVLQQNT-LNFDLSVEEIFPALLAGATLAPSREIFGSEGTENHGIYPTVLHL 11555
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ A++ L ++L +G+ LS + + + +L N Y
Sbjct: 11556 TAAHWHTLVAEWHNQPQAAAQRLAEVRLINVTGDALSAQKLKLWDEV--RPAHTRLINTY 11613
Query: 256 GSTEVMGDVT--YYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
G TE T Y + + + IG+P+ N IYLLD P GE+++
Sbjct: 11614 GPTEATVSCTAAYVSHDAAAGSEGSGNATIGKPMANTRIYLLDAHQQPVPYGVAGEIFIG 11673
Query: 314 GANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ A RF +P + PE R+Y+TGD + G + Y GR D QVK+
Sbjct: 11674 GDGVARGYLNLEEVNAERFLADPFSNSPE-ARMYKTGDLARYMADGRIEYLGRNDFQVKV 11732
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L GV + VV+ G+ ++ +V +P A A + +L
Sbjct: 11733 RGFRIELGEIEARLGNCTGVKEAVVIAREDTPGDKRLVAYVVGQPQASLDAASLHAELAP 11792
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++++PL N K+DR+ L
Sbjct: 11793 QLAEYMLPSAFVILDALPLTPNRKLDRKAL 11822
Score = 164 bits (398), Expect = 9e-39
Identities = 128/442 (28%), Positives = 210/442 (47%), Gaps = 29/442 (6%)
Query: 24 LATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELAQ 83
LA K GAAYVP++ + P R +L+D V+ D G+ + L
Sbjct: 618 LAIIKCGAAYVPLDINAPAERQAFMLQDCGARQVLTLSRHD----LPDGIQRIDLDLLEL 673
Query: 84 EATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPY 143
++ A P+ + +++S+A ++YTSGSTG+PKGV + + A+ +RL +
Sbjct: 674 QS---DAPNPVHS-----ASAESVAYIMYTSGSTGMPKGVLVPHRAV-SRLVLNNGYADF 724
Query: 144 SDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRET--TRDPQKLVNIERLVLVPTL 201
+ + + + + F S ++W PLL+G ++++ + + D + + + + V V +
Sbjct: 725 NAGDRV-AFASNPAFDASTLDVWAPLLNGGCVVVVEQSVLLSLDEFRALLLSQSVSVLWM 783
Query: 202 LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVM 261
+ A G L RL+ + G+ L + + + L N YG TE
Sbjct: 784 TAGLFHQYASG-LMEALARLRYLIVGGDVLDPAVIA---RVLAEGAPQHLLNGYGPTEAT 839
Query: 262 GDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGY 321
T + + IPIGRP+ N +Y+LD P GE+++ G +A GY
Sbjct: 840 TFSTTHEITSVGS----GGIPIGRPIGNSQVYVLDTLRQPVAVGVAGELYIGGQGVAKGY 895
Query: 322 VGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRVDLL 378
+ A +F NP + LYRTGD G G V Y GR D QVKIRG R++L
Sbjct: 896 LNRPELNATQFVANPFSDDAG-ALLYRTGDLGRWNADGIVEYLGRNDDQVKIRGFRIELG 954
Query: 379 EVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYMMP 438
E+E L + PGV + VVL + + ++ +V + + SA + +L ++L YM+P
Sbjct: 955 EIEARLVECPGVREAVVLARQDESAHKRLVAYVVGEENSALSAVELRRELAASLAEYMVP 1014
Query: 439 QVIEV-ESIPLLVNGKVDRQGL 459
V +S PL NGK+DR+ L
Sbjct: 1015 SAFMVLDSFPLTANGKLDRRAL 1036
Score = 163 bits (397), Expect = 1e-38
Identities = 135/451 (29%), Positives = 212/451 (47%), Gaps = 35/451 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ++LAT K GAAY+ ++ P+ R+ +L+D+E +++ + P +
Sbjct: 12450 LTSMLATLKCGAAYLALDRLAPEERVRFMLEDSEALMLL----TRSELTAPETTPRLDLD 12505
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN--RLWWQ 137
L S + P+ A + ++ A ++YTSGSTGIPKGV ++++ I R +
Sbjct: 12506 TLD---LSVAGQGPV--ALAAEVAGETPACIIYTSGSTGIPKGVIVTHNGIVRLVRDNYD 12560
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
FR +++ + + F S EIWG LL+G +I+ +P + +
Sbjct: 12561 FR------ADDRVAFSSNPAFDASSPEIWGALLNGGQSIIVEPSVLLEPAAFAALLKRHA 12614
Query: 198 VPTLLRSILMY-LALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + S ++ L G L L++ C GE + F + + +L N YG
Sbjct: 12615 VTVMFSSTALFNLYAGLIPEALAGLRMLECGGERADP---ASFRRVREHSSQVRLFNGYG 12671
Query: 257 STEVMGDVTYYVLEGSDQLDLYP---TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
TE T Y + D+ P ++PIG+P N IYLLD P GE+++
Sbjct: 12672 PTEATTCATRY-----EVFDVQPGTLSLPIGKPNANVRIYLLDVCGEPVPMGSVGEIYIG 12726
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ A RF D+P + Q RLYRTGD L G + Y R D QVK+
Sbjct: 12727 GVGVALGYLNRPELSAERFSDDPFSQQAG-ARLYRTGDLARWLPDGNLEYLARNDGQVKV 12785
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART-SAQHIEGKLR 429
RG RV+L EVE +L GV VV+ G+ ++ + T + + +L
Sbjct: 12786 RGFRVELGEVESSLHGCDGVRNSVVVAREDSPGDTRLVAYYTVHADVEAPEPEALRAQLS 12845
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ L YM+P V I + +PL +NGKVD Q L
Sbjct: 12846 AGLPEYMVPSVFICLPDLPLTLNGKVDVQAL 12876
>UniRef50_Q0SKF9 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 8928
Score = 231 bits (564), Expect = 7e-59
Identities = 179/567 (31%), Positives = 270/567 (47%), Gaps = 34/567 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A K GAAYVP++P P RI ++++ AEP+ V+ S D +S A E
Sbjct: 1856 MIAIYAVEKTGAAYVPLDPDHPASRIAYVIESAEPACVL-TSSRDRCEGVDSAAGAAVIE 1914
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + AE P+ DS A V+YTSGSTG PKGV +S+ AI NRL W
Sbjct: 1915 IDTLNLSRRPSTPITAAERGGPIHPDSTAYVIYTSGSTGRPKGVAVSHRAIVNRLLWMQD 1974
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
T+ D ++ + KT +TF SV E++ PL G L++ + + RDP L +I + V
Sbjct: 1975 TYRM-DHTDVVLQKTPVTFDVSVWELFWPLEVGARLVLAAPDGHRDPTYLSHIIADHQVT 2033
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L G L+ CSGE L A + F+ FG+ L N YG
Sbjct: 2034 TMHFVPSMLAVFTAGAEPELCGSLRQVFCSGEALPPATA-DAFREFGSA---ALHNLYGP 2089
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVTY+ D+ ++PIG P+ N +Y+LD L P GE+++AG L
Sbjct: 2090 TEAAVDVTYWECTEGDRA----SVPIGAPVWNTQVYVLDSRLHPVPVGVHGELYLAGIQL 2145
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GYVG ++RF NP QR+YRTGD G + Y GR D QVK+RG R
Sbjct: 2146 ARGYVGRSDLTSDRFVANPFGAPG--QRMYRTGDVVRWRADGNIEYIGRRDFQVKLRGQR 2203
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L EVE A+ P V + VV + + ++G+V GA + AL
Sbjct: 2204 IELGEVEAAVLAHPSVAQAVVTVHRSEATGESLVGYVIPVAGADIDTAVVRDAAAEALPA 2263
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P ++I ++ PL GK+DR L + E + S
Sbjct: 2264 YMVPTRIIVLDRFPLGATGKLDRGAL----------PEPEF---LSPSAEFVTPRNPIEE 2310
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
++ A L A R + + F++LGGNSL + + ++ G + + + A T+
Sbjct: 2311 ILASIFADLLDAPR--IGVYDSFFDLGGNSLVATRLVARVNAALGSRIGVREIFDAPTVA 2368
Query: 553 EVLSKMSTDPNGGADSKEATFTAVPMR 579
+ +++ ++ GA+ A P R
Sbjct: 2369 TLATRIESEAVQGAERPPLVAGARPDR 2395
Score = 203 bits (495), Expect = 2e-50
Identities = 164/557 (29%), Positives = 253/557 (45%), Gaps = 41/557 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA K G Y+P++ ++P R+ + +DA P+ VI + D S +S P +
Sbjct: 5532 IIALLAVIKTGGGYLPVDITYPADRLAFVFEDAAPNCVI-TTTGDVSALPDSETPAILLD 5590
Query: 80 --ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E + S DA+ + PL S S+A V+YTSGSTG PKGV +S+ N L
Sbjct: 5591 DPETTADLAQQSPATITDADRVTPLDSSSVAYVIYTSGSTGRPKGVVVSHR---NVLTLF 5647
Query: 138 FRTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
T P +E VW + F SV E+WGPLL+G L+++ T R P+ + R
Sbjct: 5648 ANTQPLYGFDENDVWTMFHSYAFDFSVWELWGPLLYGGRLVVVDYYTARSPEMFHELLRN 5707
Query: 196 VLVPTLLRSILMYLALGPASRPLRR---------LKLWVCSGETLSKELASEFFKYFGNE 246
V L ++ + L R + L+ + GE L ++ ++
Sbjct: 5708 EQVTVLNQTPTAFYQLAETDRIVSEIDVNAAALALRYVIFGGEALDLGQLGRWYSRH-DD 5766
Query: 247 DGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSE 306
L N YG TE V+Y L+ ++ IGR + +++LD L P
Sbjct: 5767 SAPTLVNMYGITETTVHVSYLALDREFAESASASV-IGRGIAGLHVHVLDRRLHPVPPGT 5825
Query: 307 PGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGR 363
GE++V+G + GY+G G ++RF +P +P R+YRTGD G + Y GR
Sbjct: 5826 IGEMYVSGDQVTRGYLGRAGLSSSRFVADP--LRPG-ARMYRTGDLARWNTDGQLEYLGR 5882
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQH 423
+D QVKIRG R++L E+E AL + G+ + VVL G ++G+V + GA
Sbjct: 5883 SDFQVKIRGFRIELGEIESALLRYRGIAQAVVLTRDDGHGGHRLIGYVVPESGATVEVSS 5942
Query: 424 IEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSX 482
+ + LT YM+P + V +++PL NGK+DR+ L E S
Sbjct: 5943 ALEFVGTQLTSYMVPATLVVLDALPLTSNGKLDRRAL------------PEPDFGARVSA 5990
Query: 483 XXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
VLG + G + F+ LGG+S+ SI + + + G +
Sbjct: 5991 GRAPATEMETVLAGLFAEVLGLESVG---VDDSFFALGGDSIMSIQLVARAKAAGVVLTP 6047
Query: 543 SDFLGASTLGEVLSKMS 559
D A T+ + S
Sbjct: 6048 RDVFEAKTVAALAEAAS 6064
Score = 170 bits (414), Expect = 1e-40
Identities = 147/539 (27%), Positives = 245/539 (45%), Gaps = 39/539 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
++++L A K GAA+VP++P++P RI H+L D+ +L + P++ +
Sbjct: 2920 SVLSLWAVAKTGAAFVPVDPNYPTDRIVHMLSDSGAALALTVAEFRPTLPDCTSYVVVDA 2979
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E ++HSA DA+ PL ++ A ++YTSGSTG PKGV +++ + N +
Sbjct: 2980 PGFDDEVSAHSAAVVTDADRTHPLALENPAYLIYTSGSTGTPKGVVVTHRGLANFATDER 3039
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
F + + + +F S+ E+ + G A ++++ + +L ++ R V
Sbjct: 3040 VRFGVTPRSRTLHFSSP-SFDASILELLLAVGSG-ATMVIAPASVIGGTELADVLREGRV 3097
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ ++ PA L +L+ G+ EL +++ G ++ N YG T
Sbjct: 3098 THAFITPAAMASVDPAG--LDQLECVATGGDVCPPELVAQWVT-----GGRRMFNAYGPT 3150
Query: 259 E--VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E V+ VT ++ G + IGRP +LD L P + GE++V+G+
Sbjct: 3151 EATVVSSVTGPMIPGEG-------VTIGRPPMGTGEMVLDSRLHPVPNGVTGELYVSGSG 3203
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGH 373
LA GY G A RF NP+ R+YRTGD G + Y GR+D QVKIRG
Sbjct: 3204 LARGYKDRAGTTAERFVANPYGGLGA--RMYRTGDLARWNGAGQLEYLGRSDFQVKIRGF 3261
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E AL + PGV + VV + G ++G++ GA + + + L
Sbjct: 3262 RIELGEIETALTRYPGVARSVVSAHRGSTGANRLVGYLVPTAGAELDPEAVLEFVGGFLA 3321
Query: 434 HYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P +I ++ +PL GK+DR+ L E S
Sbjct: 3322 PYMVPSALIVLDELPLTPAGKLDRRAL------------PEPDFGARVSTGRAPVSEMEE 3369
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
VLG + G + F+ LGG+S+ SI + + + G + D A T+
Sbjct: 3370 VLAGLFAEVLGLESAG---VEDSFFALGGDSIMSIQLVARAKAAGVVLTPRDVFEAKTV 3425
Score = 156 bits (379), Expect = 2e-36
Identities = 127/450 (28%), Positives = 216/450 (48%), Gaps = 28/450 (6%)
Query: 19 TIMALLATW---KAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPF 75
+I ++LATW K+GAA+VP++P++P RI H+L D+ ++V +A S E+ P+
Sbjct: 791 SIESVLATWAVAKSGAAFVPVDPNYPADRIEHMLTDSG-AVVGLTVAAHRSSLPET-TPW 848
Query: 76 ASFEELA--QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
++ + ++ H+A DA+ L PL + A ++YTSGSTG PKGV ++++ + N
Sbjct: 849 LVMDDASFGRDLAQHAAGTVADADRLRPLRTADPAYLIYTSGSTGTPKGVVVTHAGLANF 908
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
+ + F + + + +F S+ E+ + G A ++++ T +L ++
Sbjct: 909 AEDERQRFAVTAGSRTLHFSSP-SFDASILELLLAVGAG-ATMVVAPSTVYGGTELADLL 966
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V + ++ P L ++ V GE+ L +++ G + N
Sbjct: 967 SRERVTHAFVTPAALASVDPTG--LDHIRCVVTGGESCPPALVAQW------APGRVMFN 1018
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE V + L + + IGRP C + +LD L P PGE+++
Sbjct: 1019 AYGPTEAT-----VVASVAGPLTVGEPVTIGRPSRGCGLLVLDSRLHPVPRGVPGELYIT 1073
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G +A GY A RF +PH E R+YRTGD G + Y GRTD QVKI
Sbjct: 1074 GDGVARGYHNRSIPTAERFVADPHGAPGE--RMYRTGDLARWNAAGQLEYLGRTDFQVKI 1131
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E++ + P V + G+ ++ +V + G I +
Sbjct: 1132 RGFRIELGEIDAVVRSHPSVAFATTVGRTAPSGDTVLVTYVLPEDGTDIVVGDILEHAAA 1191
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
AL +M+P +V+ + +PL GK+DR+ L
Sbjct: 1192 ALPAHMVPARVMVLREVPLTPAGKLDRKAL 1221
Score = 151 bits (365), Expect = 9e-35
Identities = 125/447 (27%), Positives = 207/447 (46%), Gaps = 25/447 (5%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+ A K GAA+VP++P++P RI H+L D+ ++ + + + ++ VP+
Sbjct: 7090 SVLAVWAVAKTGAAFVPVDPNYPMDRIEHMLTDSGATIGLTMAAYEKAL--PDSVPWLQL 7147
Query: 79 E--ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ + + S A D++ +P++ D+ A ++YTSGSTG PKGV +++ + N
Sbjct: 7148 DSPKFEKACQSKPALPVADSDRRSPISLDNAAYIVYTSGSTGKPKGVVVTHEGLDNFAED 7207
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
Q + F + + + T +F SV E G A ++++ T +L + R
Sbjct: 7208 QRQRFAAAQTSRTLHFSTP-SFDGSVFEYLQAFGVG-ATMVIAPPTVYGGAELAELIRSE 7265
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + + P L + V GE EL + + G +L+N YG
Sbjct: 7266 HVTHAFVTTAALSTVDPTG--LDEFQHVVFGGEACPPELVTRW------APGRQLSNAYG 7317
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T + SD + + I +G P+ +LD L P PGE+++ GA
Sbjct: 7318 PTE-----TTVMANISDPMTVGDPITLGGPIRGVGELVLDSRLQPVPVGVPGELYITGAG 7372
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
LA GY + RF NP E R+YRTGD V Y GR+D QVKIRG
Sbjct: 7373 LARGYHRRPELSSQRFVANPFGEAGE--RMYRTGDIVRWRADHTVEYVGRSDFQVKIRGF 7430
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E++ +A PGV L G+ ++ ++ + L + L
Sbjct: 7431 RIELGEIDNEIATFPGVSFAATLGVPGPSGDTVLVTYLLPNTAGGVDPAELTAHLSTRLP 7490
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
+M+P V+ ++ IPL GK+DR L
Sbjct: 7491 AHMVPTSVMFLDEIPLTPVGKLDRSAL 7517
Score = 147 bits (356), Expect = 1e-33
Identities = 132/451 (29%), Positives = 211/451 (46%), Gaps = 30/451 (6%)
Query: 19 TIMALLATW---KAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPF 75
+I ++LA W K GAA+VP++P++P+ R+ H++ D+ + + + AD ++ V +
Sbjct: 4463 SIESVLAVWSITKTGAAFVPVDPTYPRERVEHMVTDSGCTFGLRLE-ADHGRLPDT-VRW 4520
Query: 76 ASFE--ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
+ + E A + S D D + +APL A V+YTSGSTG PKGV +S+ + N
Sbjct: 4521 LTLDDTETATAIRAMSTDTVTDDDRVAPLRFAHPAYVIYTSGSTGKPKGVVVSHRGLDNF 4580
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
Q RT +DS + ++ +F SV E G ++I+ + +
Sbjct: 4581 AEEQ-RTRYATDSTSRALHFSSPSFDASVLEYLLSFAVGATMVIVPPSVYGGEE----LA 4635
Query: 194 RLVLVPTLLRSILMYLALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L+ + + AL L + V GE + EL + + G +
Sbjct: 4636 ELIRTEGVTHGFVTPAALASVDPEGLEVFQNVVAGGEAVPPELVTRW------APGRTMY 4689
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE T + SD L + T+ IG P+ + +LD L P GE+++
Sbjct: 4690 NGYGPTE-----TTIMSNLSDHLQVGETVTIGAPVRGVSEVILDSRLQPVSVGVAGELYI 4744
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG-AVLYAGRTDAQVK 369
+G LA GY G + RF NP+ + R+YRTGD V Y GRTD QVK
Sbjct: 4745 SGEGLARGYHARAGLTSERFVANPYGEPGD--RMYRTGDLARWRSDHTVEYLGRTDFQVK 4802
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG R++L +++ ALA P V V L G+ ++ +V + + ++
Sbjct: 4803 IRGFRIELGDIDSALAAHPSVAFAVTLGRPGPAGDTVLVSYVLPEAESALEPPELKEWTA 4862
Query: 430 SALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
+ L +M+P I + + IPL GK+DR L
Sbjct: 4863 NLLPAHMVPSSIMILDEIPLTPVGKLDRAAL 4893
Score = 135 bits (327), Expect = 4e-30
Identities = 144/571 (25%), Positives = 246/571 (43%), Gaps = 49/571 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF- 78
++++ + K+GAA+VP++P++P+ RI ++L D S+ + ++ VP+
Sbjct: 8148 VVSIWSVAKSGAAFVPVDPTYPRDRIDYMLTDCRASVGLTVAGRRDNL--PDTVPWLVLD 8205
Query: 79 -EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E A++ + S+ DA+ PL A ++YTSGSTG PKGV +++ + N +
Sbjct: 8206 DESFAEQVAAVSSSPVTDADRTRPLHLAHPAYLIYTSGSTGKPKGVIVTHRGMANLTAEE 8265
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
F + + + +F S+ E+ A +++ T +L ++ R
Sbjct: 8266 HERFQVTHESRVSHLASP-SFDASIFELM-MAFGASARVVIVPPTVFGGTELADLFRRNA 8323
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + ++ L L++ +GE EL + K+ +GY G
Sbjct: 8324 VTHAFITPTALSSIEDVG--LESLRVLAVAGEACPPELVEIWGKHRNMHNGY------GP 8375
Query: 258 TEVMGDVTYYVLEGSDQLDLYP--TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE ++ S + P + IG P +LDE L P PGE+++ G
Sbjct: 8376 TET-------TIQASVSAPMRPGGVVNIGAPALGFGSLVLDERLQPVPVGVPGELYITGP 8428
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG--AVLYAGRTDAQVKIR 371
LA GY + RF P +P +R+YRTGD +G + Y GRTD QVK+R
Sbjct: 8429 GLARGYHNRSALTSERFVACPFG-EPG-RRMYRTGDV-VRWRGDHTIEYIGRTDFQVKVR 8485
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E++ LA+ P V + + G+ + +V G +
Sbjct: 8486 GFRIELGEIDAVLARHPAVAFAATIGHTGPSGDTLLASYVRAAEGHDLEPAELRTHAADR 8545
Query: 432 LTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L +M+P V+ ++ IP+ GK+DR+ L T +
Sbjct: 8546 LPAHMVPSAVVVLDQIPMTPVGKLDRKALPAPEFGTTG------------AAFRAPTTAT 8593
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEI-SDFLGA 548
VLG GT F++LGGNS+ + IT L++R G + + S FL
Sbjct: 8594 ERIIVEAFAEVLGVDRVGT---ADSFFDLGGNSIVATRVITVLQERLGRQIPLQSMFLDP 8650
Query: 549 STLGEVLSKMSTDPNGGADSKEATFTAVPMR 579
+ G L ++ T+ G+ EA +P+R
Sbjct: 8651 TPAGLAL-RVDTENAAGSPVDEALGVVIPLR 8680
>UniRef50_Q2N3S9 Cluster: Hybrid nonribosomal peptide
synthetase/polyketide synthase; n=2; Proteobacteria|Rep:
Hybrid nonribosomal peptide synthetase/polyketide
synthase - Polyangium cellulosum (Sorangium cellulosum)
Length = 4641
Score = 230 bits (563), Expect = 9e-59
Identities = 150/446 (33%), Positives = 229/446 (51%), Gaps = 22/446 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL+A KAG AY+P+EP++P+ R+ + +DA ++++ S + +G
Sbjct: 1070 VVALVAILKAGGAYLPLEPTYPEQRLEFMARDAGVAVLLTQSSFSGVLAGFTGTRLCLDT 1129
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E A +S+SAD P + + +A V+YTSGSTG+PKG LS+ AICNRL W
Sbjct: 1130 E-ASRLSSYSADSPR-----VEVRPEHLAYVIYTSGSTGMPKGCMLSHRAICNRLHWMQE 1183
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ + + + + KT TF SV E + PL+ G +++ + RDP L + E V
Sbjct: 1184 AYALTPLDRV-LQKTPFTFDVSVWEFFWPLITGARIVLAAPGAERDPAALAGLIQEHGVT 1242
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L P + L+ SGE L L F + L N YG
Sbjct: 1243 ACHFVPSMLRLFLDEPRAAGCASLRHVFFSGEALPYPLMERALSTFSAQ----LHNLYGP 1298
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DV+++ D +PIGRP+ N +Y+LDE+ P R + GE+++AG L
Sbjct: 1299 TEAAVDVSFWKCNLRDDRK----VPIGRPIANIRLYILDEQQRPVRPDQTGELYIAGVGL 1354
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF +P P R+Y+TGD L G + + GR D Q+K+RG R
Sbjct: 1355 ARGYLNRPELTAERFVRDPFDPSPG-ARMYKTGDRAAWLPDGNIDFLGRMDGQIKLRGLR 1413
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E AL V + V D G+P ++ +V + GA S Q + L S+L
Sbjct: 1414 IELGEIEAALLGHEAVREAAVAVRDADSGDPRLVAYVVLRDGASFSPQVMRRFLESSLPR 1473
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P Q ++V IP+ +GK+DR L
Sbjct: 1474 YMVPNQFVQVAGIPVTAHGKMDRAAL 1499
>UniRef50_Q4C3C2 Cluster: Amino acid adenylation; n=1; Crocosphaera
watsonii WH 8501|Rep: Amino acid adenylation -
Crocosphaera watsonii
Length = 1539
Score = 229 bits (560), Expect = 2e-58
Identities = 156/521 (29%), Positives = 257/521 (49%), Gaps = 34/521 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP+EP++P RI ++L+D++ ++++ + ++ + G
Sbjct: 529 VIGLLAILKAGGAYVPIEPTYPTERIQYLLEDSKVAILLTQNHLTTTLPEYQGRIICL-- 586
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E S+ + + +E L+ D++ ++YTSGSTG PKG ++ + NRL W
Sbjct: 587 DTKSELMSNGGKQNLVSE----LSIDNLIYIIYTSGSTGKPKGTMNTHQGVVNRLLWMQD 642
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
T+ + + + + KT +F S E W PL+ G L++ E +DP L+ + E+ +
Sbjct: 643 TYQLTTRDRV-LQKTPFSFDVSAWEFWWPLMTGACLVVAQPEGHKDPTYLIKLIKEQQIT 701
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + S+L L+ SGE L+ L +FF E L N YG
Sbjct: 702 ILHFVPSMLQIFLEEADEESCSSLREVFSSGEALTVALEEKFFSRLKAE----LHNLYGP 757
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ + + Q ++PIGRP+ N Y+LD L P PGE+++ G L
Sbjct: 758 TEAAIDVTFWQCQANSQRS---SVPIGRPIANTQTYILDVNLQPVPVGVPGELYLGGVQL 814
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF +NP + RLY+TGD L G + Y GR D QVKIRG R
Sbjct: 815 ARGYLNRPELTAERFIENPFRENFGYSRLYKTGDLVCYLPDGNIEYLGRLDNQVKIRGLR 874
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E +AQ V + VV+ G+ ++ ++ + + ++ + LR L +
Sbjct: 875 IELGEIEAQIAQYETVKEAVVIAREEIAGDKRLVAYLVPQEESTVNSSKLRKFLREKLPN 934
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P + +E +PL NGK+DR+ L DD + I
Sbjct: 935 YMIPSAFVTLEELPLTPNGKIDRKAL---------PDD--IGTQISSDEIVLPSTPIENL 983
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR 534
+LG T+ + + F+ELGG+SL + I+++R
Sbjct: 984 LAGIWAEILGIE---TVGINNNFFELGGHSLIATRVISQIR 1021
>UniRef50_Q0S7I5 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 5592
Score = 229 bits (560), Expect = 2e-58
Identities = 172/528 (32%), Positives = 258/528 (48%), Gaps = 40/528 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AYVP++ +P R+ ++L+DAEP V+ D + F SGVP +
Sbjct: 2065 MVALLAVGKAGGAYVPLDTGYPADRLAYMLEDAEPVCVLTDGTVP---FAGSGVP----Q 2117
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+A + S EP+ LAP A V+YTSGSTG PKGV + ++ I NRL W R
Sbjct: 2118 VRVSDAAAFSP-EPLTGVALAP---QHPAYVIYTSGSTGRPKGVVVPHAGIVNRLLWVQR 2173
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLVL 197
P + S+ + KT +F SV E +GPLL G L++ + +DP L + I R +
Sbjct: 2174 FRPITPSDTV-FQKTPSSFDVSVLEFFGPLLAGATLVLARPDGHKDPAYLADVIIRRSIT 2232
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L PA+ L++ CSGE L A + G +L N YG
Sbjct: 2233 RVHFVPSMLEVFLAEPAAARCTGLRIISCSGEALPVASARRVAELL---PGVELDNLYGP 2289
Query: 258 TEVMGDVTYYV-LEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DV+Y ++G D P++PIG P N +Y+LD L P GE++++G
Sbjct: 2290 TEASVDVSYAASVQGIDASA--PSVPIGLPTSNTGLYVLDRYLQPVPAGAAGELYLSGPQ 2347
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
LA GY+G G A RF +P + R+YRTGD + GAV Y GR D QVK+RG
Sbjct: 2348 LARGYLGRPGLSAERFVADPFSRTGS--RMYRTGDVARVNADGAVEYVGRVDDQVKLRGF 2405
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E +A PGV + + G +++G+V + +L +AL
Sbjct: 2406 RIELGEIEAQMAACPGVRQAAAVVRTDRPGQQQLVGYVV----GDADVDDVRARLTAALP 2461
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
+M+P + V P+ +GK+DR L + + + ++ +
Sbjct: 2462 EFMVPVAFVTVPEFPVGPSGKLDRTALPAPDFSAHTSSGQTTSLPV-------LESGPAA 2514
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYV 540
VLG GT+ + F+ LGG+S+ +I + R G V
Sbjct: 2515 VLAAHYAEVLG---LGTVGVDDDFFALGGDSILAIRLVNLARREGITV 2559
Score = 186 bits (452), Expect = 3e-45
Identities = 144/448 (32%), Positives = 217/448 (48%), Gaps = 27/448 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA +G A+VP++PS+P+ R T +L DA +LV+ E VP
Sbjct: 542 VIGLLAVMCSGGAFVPLDPSWPEDRRTSVLADAGAALVLTGPGGVTDA-GERAVPV---- 596
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+LA A AD+P + + + +A V++TSGSTG PKG + + A+C RL WQ
Sbjct: 597 DLAAWAY---ADQPTEPPAVT-VQGSRLAYVIFTSGSTGRPKGAMIRHEAVCARLLWQRD 652
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLV 196
+ ++K L+F SV EI PL+ G L++ RDPQ L+++ E +
Sbjct: 653 EILGFGPADASLFKAPLSFDISVNEILLPLVAGGRLVVAEPGGERDPQYLLDLIAGESVT 712
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + + + L L + L LK C GE L+ L F+ F ++ L + YG
Sbjct: 713 FVYLVSSMLDVLLDLSRGTDLLAALKHVWCGGEVLTPRL----FERFRSQLAITLYHGYG 768
Query: 257 STEVMGDVTYYVL-EGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
E V++ + E + ++ IGRP N +Y+LDE L+P GE++ G
Sbjct: 769 PAEATIGVSHVIYRENAARI----ATSIGRPNPNTQLYVLDEHLNPVPLGTGGELYAGGF 824
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRG 372
L GYV G A+RF NP A + RLYRTGD G++ + GR D QVKIRG
Sbjct: 825 LLGRGYVDAPGLTASRFVANPFAN--DGSRLYRTGDLARWAPDGSLDFLGRADNQVKIRG 882
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L +VE + P V V+ G + +V K + + S L
Sbjct: 883 MRLELEDVEAGIVSHPDVRHSAVVVRETPSGAKYLAAYVVAKQDSVPDVAELRVWASSKL 942
Query: 433 THYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + ++ PL NGK+DR+ L
Sbjct: 943 PEYMVPSAFVVLDRFPLTPNGKLDRRAL 970
Score = 148 bits (358), Expect = 7e-34
Identities = 161/569 (28%), Positives = 247/569 (43%), Gaps = 63/569 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL A + G+AY+P+E P R+ +L DA P++++ ++ A+ +
Sbjct: 3573 VVALFAVLRTGSAYLPLELDHPAERLLAMLDDARPTVLVTTSEVAGTLAA------ATVD 3626
Query: 80 ELAQEATSHS--ADEPMDAETL---APLTS---DSIAIVLYTSGSTGIPKGVRLSYSAIC 131
LA ++ A P+ L AP T D A V+YTSGSTG PKGV Y +
Sbjct: 3627 TLAVDSVDFGGVASAPLSEAELGGFAPGTPGRLDHPAYVIYTSGSTGKPKGVVTPYRGLT 3686
Query: 132 NRLWWQFRTFPY------SDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRD 185
N + + R + + + + T D E L+ G + I RD
Sbjct: 3687 N-MQFNHREAIFEPVVTAAGGRRLRIAHTVSFAFDMSWEELLWLVEGHEVHICDENLRRD 3745
Query: 186 PQKLVN------IERLVLVPTLLRSILMYLAL--GPASRPLRRLKLWVCSGETLSKELAS 237
+ LV I+ + + PT + ++ L GP R L + GE +S +
Sbjct: 3746 AEALVAYCDTQAIDVVNVTPTYAQHLVEEGLLDDGPGRH---RPPLVLLGGEAVSDSV-- 3800
Query: 238 EFFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDE 297
+ + DG N YG TE T L PT+ G P+ N + Y+LD
Sbjct: 3801 --WNRLRDTDGTVGYNLYGPTEY----TINTLGAGTADSATPTV--GTPIWNTSAYVLDA 3852
Query: 298 ELSPTRDSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK 355
L P D PGE++++G LA GY+ A RF +P E R+YRTGD +
Sbjct: 3853 WLRPVPDGVPGELYISGVGLARGYLDRFALTAERFVADPFE---ESVRMYRTGDLVRRRE 3909
Query: 356 -GAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK 414
G + + GRTD QVKIRGHRV+L E+ AL + V + V+ G I+G+
Sbjct: 3910 DGNLDFLGRTDDQVKIRGHRVELGEIASALEALDDVRQAAVVVDSGPGGFKRIVGYAVVS 3969
Query: 415 PGARTSAQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAE 473
LR+ L YM+P VIEV+S+P+ VNGK+D + L + + A
Sbjct: 3970 TCQPRDVNKYSQALRATLPDYMVPAAVIEVDSLPMTVNGKLDVKALPSADDVLGRSGGAR 4029
Query: 474 VAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL 533
D G +LG A G + F++LGG+SL + I++
Sbjct: 4030 TEPRTD----------TERVLSGLFGEILGVPAPG---VDDDFFDLGGHSLLATRLISRA 4076
Query: 534 RDR-GYYVEISDFLGASTLGEVLSKMSTD 561
R + + D A T+ E+ +++ D
Sbjct: 4077 RAALDTDLTLRDLFEAPTVAELAARIGDD 4105
Score = 128 bits (309), Expect = 6e-28
Identities = 123/451 (27%), Positives = 199/451 (44%), Gaps = 31/451 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ +L K GAAY+P++ + P RI+++L D+ +++ P + G+ +
Sbjct: 4642 VAVVLGVLKLGAAYLPLDLNHPSDRISYMLADSAARVLVTTVGESPRIADVDGLTRVLLD 4701
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + P P D A V+YTSGSTG PKG L++ I + + R
Sbjct: 4702 D--ESVVTELETGPAVQVPRPPQGLDHAAYVIYTSGSTGKPKGAILTHDGIPSLVATAER 4759
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + ++ F +V E+ L G L+I+ E+ +L + V
Sbjct: 4760 RMKLVPGSVVMQF-ASIGFDVAVFELSMALCTGSRLVIVPDESRVAGPELTDFMAAHAVT 4818
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + AL P+ + + ET+ EL + + L YG TE
Sbjct: 4819 HAIIPPSLLAAL-PSGCDVPEGCTVLVGTETVPPELIGRW------AERLNLLAAYGLTE 4871
Query: 260 VMGDVTYYVLE-GSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
+ T + + G D +PIG P N Y+LD+ L P GE+++AG LA
Sbjct: 4872 ATVNNTLWQAQPGWDS-----AVPIGIPDPNEQAYVLDDRLQPVPPGVAGELYIAGRGLA 4926
Query: 319 AGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+G RF +P R+YRTGD G + + GR D QVKIRG R+
Sbjct: 4927 RGYLGRPDLTSVRFVPSPFGDAG--TRMYRTGDRARWRADGNIDFLGRVDDQVKIRGFRI 4984
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNP--EILGFVTTKPG---ARTSAQHIEGKLRS 430
+L E+ AL P V + V+ DR ++G+VT+ G + + + +
Sbjct: 4985 ELGEIIAALGSHPEVKQSAVVA---DRSGDIVRLVGYVTSADGHAAGQIDPRAVREHAAA 5041
Query: 431 ALTHYMMPQVIEV--ESIPLLVNGKVDRQGL 459
L YM+P ++ V E +PL NGK+DR+ L
Sbjct: 5042 RLPDYMVPTLVVVLDEDLPLTPNGKLDRKAL 5072
>UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide synthetase
protein; n=2; Proteobacteria|Rep: Probable non ribosomal
peptide synthetase protein - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 5953
Score = 229 bits (559), Expect = 3e-58
Identities = 158/450 (35%), Positives = 233/450 (51%), Gaps = 33/450 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG YVP++PS+PQ R+ ++L+D+ P V+ A + ++ G
Sbjct: 4859 VVGLLGILKAGGGYVPLDPSYPQDRLAYMLEDSAPVAVL----AQSNTREQLGALSVPVL 4914
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+LA + +P E L P +A V+YTSGSTG PKGV + + + NRL W R
Sbjct: 4915 DLASPLEGEAEHDP-QVEALKP---HHLAYVIYTSGSTGQPKGVEATIAGLANRLQWFLR 4970
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ------KLVNIE 193
+ KT++ FVD+V E G LL G +L++ +D + +
Sbjct: 4971 --DVLTEAPVTALKTSIGFVDAVTETLGTLLAGGSLVVFDNAAVKDLSVFARRLRQTGVS 5028
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
LV+VP+LL+ YL R L L+ VCSGE L+ ELA + + +L N
Sbjct: 5029 HLVVVPSLLK----YLLQSGEPR-LDGLRTLVCSGERLAPELARQCLAAYPQ---VRLLN 5080
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
FYGS+EV GD T+Y G + + + IGRP+ N IY+LD +P PGE+ V
Sbjct: 5081 FYGSSEVNGDATFYRYAGPEHVPAHSV--IGRPIANTQIYILDAYGAPVPIGVPGEIHVG 5138
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA +A GY+ G A RF +P R+YRTGD G G ++Y GR D QVK+
Sbjct: 5139 GACVARGYLHRPGLTAERFVADPFHGDGR-ARMYRTGDLGCWQADGNIVYLGRNDHQVKL 5197
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++ E+E LA GV + VVL G P ++ + + A AQ + +L++
Sbjct: 5198 RGFRIEPGEIEARLAGCEGVREAVVLIRDDGVGEPRLVAYYSGP--AALPAQALRAQLQA 5255
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
AL YM+P + +E +PL +GK++R L
Sbjct: 5256 ALPAYMVPAAYVYLERMPLTSSGKLNRHAL 5285
Score = 227 bits (554), Expect = 1e-57
Identities = 157/451 (34%), Positives = 234/451 (51%), Gaps = 35/451 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG YVP++PS+PQ R+T++L+D+ P V+ + +E + S
Sbjct: 1683 VVGLLGILKAGGGYVPLDPSYPQDRLTYMLEDSAPVAVLTQ-----GLVREQ-LGMLSVP 1736
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + A+ E L P +A V+YTSGSTG PKGV + + NRLWW +
Sbjct: 1737 VLDLDGPQEDAEHDPQVEALKP---HHLAYVIYTSGSTGRPKGVMNEHRGVVNRLWWAQQ 1793
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VNIE 193
T+ S+ + + KT F SV E++ PLL G L++ E + P L I
Sbjct: 1794 TYRLDASDRV-LQKTPFGFDVSVWELFWPLLAGARLVMARPEGHKAPAYLAATIEQAGIT 1852
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L+ L + G + LRR+ +CSGE L L F + + L N
Sbjct: 1853 TLHFVPSMLQLFLDQVEAG-RCQGLRRM---LCSGEALPHALQQRSLARFPHSE---LHN 1905
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE DVT + +++P +PIGRP+ N IY+LD P GE+++
Sbjct: 1906 LYGPTEAAIDVTAWRCNA----EIHPGVVPIGRPIANTQIYVLDAYRQPVPLGVTGEIYI 1961
Query: 313 AGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
GA +A GY+ A RF NP + +R+YRTGD G L G++ Y GR DAQVK
Sbjct: 1962 GGAGVARGYLNRPELTAERFVVNPFHGEGR-ERMYRTGDLGRWLPDGSLEYQGRADAQVK 2020
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++L E+E L+Q GV + VV G ++ + + G AQ + +L+
Sbjct: 2021 LRGFRIELGEIEARLSQCAGVSEAVVAMREDVPGEQRLVAYYVS--GEAIEAQTLREQLQ 2078
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
++L YM+P + +E +PL NGK+DR+GL
Sbjct: 2079 ASLPEYMVPAAYVRLEHLPLTPNGKLDRKGL 2109
Score = 196 bits (479), Expect = 1e-48
Identities = 145/449 (32%), Positives = 226/449 (50%), Gaps = 32/449 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAG +YVP++PS+P+ R+ ++L+D+ P V+ S + V +
Sbjct: 2762 VIGVLGILKAGGSYVPLDPSYPRDRLAYMLEDSAPVAVVAQ-SGTRDRLGDRPVAVVDLD 2820
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + +A EP +A L+S A V+YTSGSTG PKGV + + + N L
Sbjct: 2821 EASWQA------EPSHRPEVAGLSSHHAAYVIYTSGSTGRPKGVTVEHRQVVNLLESMRG 2874
Query: 140 TFPYSDSEEICVWK--TALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL---VNIER 194
++++ W T L F + E++ PL+ G +++L RE +R+ Q L +
Sbjct: 2875 LLAMTEADR---WPAVTTLGFDIAGLELYLPLISGAVVIVLDREVSRNAQSLSAALEGSG 2931
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
++ + + L G + RP LK +C GE L ELA G +L N
Sbjct: 2932 ATVMQATPSTWRLLLESGWSGRP--GLKA-LCGGEALPGELAGRLRARVG-----RLWNV 2983
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE + ++ +D +PIGRP+ N +Y+LD P GEV++ G
Sbjct: 2984 YGPTETTIWSSAREVDATDAGQ--GVVPIGRPIANTQMYVLDAYRQPVPLGVTGEVYIGG 3041
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
A +A GY+ A RF +NP + +R+YRTGD G L G++ Y GR DAQVK+R
Sbjct: 3042 AGVARGYLNRPELTAERFVENPFHGEGR-ERMYRTGDLGRWLPDGSLEYQGRADAQVKLR 3100
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E L Q GV + VV G ++ + + G AQ + +L+S
Sbjct: 3101 GFRIELGEIEARLLQCAGVSEAVVTVREDAPGEQRLVAYYVS--GEAIEAQTLREQLQSR 3158
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + +E +PL NGK+DR+ L
Sbjct: 3159 LPEYMVPAAYVRLERLPLTPNGKLDRKEL 3187
Score = 190 bits (464), Expect = 9e-47
Identities = 143/445 (32%), Positives = 222/445 (49%), Gaps = 33/445 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG YVP++PS+PQ R+ ++L+D+ P V+ + + S VP +
Sbjct: 3815 VIGLLGILKAGGGYVPLDPSYPQDRLAYMLEDSAPVAVLAQSNTREQLGALS-VPVLDLD 3873
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+EA H +P + L +A V+YTSGSTG PKGV + + N L W R
Sbjct: 3874 GPLEEA-EH---DPQ----VTGLEPHHLAYVIYTSGSTGRPKGVVVEHRNTVNFLAWAAR 3925
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHG-RALLILSRETTRDPQKLVNIERLVLV 198
FP + ++ T+L F SV E + PL G R ++++ D V + + V
Sbjct: 3926 AFPPASLART-LFSTSLNFDLSVFECFAPLTTGGRIDIVVNVLALGDGTHDVRL--INTV 3982
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
P+ L ++L L PA + +GE L +EL + F +L N YG +
Sbjct: 3983 PSALSALLESSGLDPAVEVVN------VAGEALKRELVE---RLFAQTQARRLYNLYGPS 4033
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E ++ ++ + IGRP+ N IY+LD P GE+++ GA +A
Sbjct: 4034 ETTTYSSWVCMDRQTGFQAH----IGRPIANTQIYVLDAYRQPVPLGVTGEIYIGGAGVA 4089
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF NP + +R+YRTGD G L G++ Y GR DAQVK+RG R+
Sbjct: 4090 RGYLNRPELTAERFVVNPFHGEGR-ERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRI 4148
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E L+Q GV + VV G ++ + + G AQ + +L+++L Y
Sbjct: 4149 ELGEIEARLSQCAGVSEAVVTMREDVPGEQRLVAYYVS--GEAIEAQTLREQLQASLPEY 4206
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGL 459
M+P + +E +PL NGK+DR+ L
Sbjct: 4207 MVPAAYVRLERLPLTPNGKLDRKEL 4231
Score = 180 bits (437), Expect = 2e-43
Identities = 134/445 (30%), Positives = 222/445 (49%), Gaps = 27/445 (6%)
Query: 24 LATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELAQ 83
LA K GA YVP++ + PQ R+ +L+D E +L++ D + A L
Sbjct: 629 LAILKCGAVYVPLDCNAPQARLRFLLEDVEAALLLTASGLDVPVL-------AGLRRL-- 679
Query: 84 EATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPY 143
+ + + +DA+ ++ A VLYTSGSTG+PKGV + + AI +RL +
Sbjct: 680 DVDGAAGNSAVDADLPPVPGGEAAAYVLYTSGSTGLPKGVVVPHRAI-SRLVLN-NGYAA 737
Query: 144 SDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVPTLLR 203
+++ + + F S ++W PLL+G ++I+ + T P++ R V L
Sbjct: 738 FCADDRMAFASNPAFDASTLDVWVPLLNGGRVVIIDQPTVLAPERFAQALRRGQVSVLWM 797
Query: 204 SILMYLALGPASRPL-RRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMG 262
+ + P+ + +L+ + G+ L + + + L N YG TE
Sbjct: 798 TAGQFHQYAPSLIGVFPQLRYLMVGGDVLDPATIAMVLREGAPQH---LLNGYGPTETTT 854
Query: 263 DVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYV 322
T ++++ + IPIGRP+ N IY+LD P GE++V GA + GY+
Sbjct: 855 FATTHLIQA---VAAGRGIPIGRPIANTQIYVLDAYQQPVPLGVTGEIYVGGAGVGLGYL 911
Query: 323 GGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVDLLE 379
A RF NP + +R+Y+TGD G L G++ Y GRTDAQVK+RG R++L E
Sbjct: 912 NRPELTAERFVVNPFHGEGR-ERMYKTGDLGRWLPDGSLEYQGRTDAQVKLRGFRIELGE 970
Query: 380 VERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT----KPGARTSAQHIEGKLRSALTHY 435
+E +L+Q GV + VV+ G ++ + + G AQ + +L+++L Y
Sbjct: 971 IEASLSQCAGVSEAVVIVREDTPGERRLVAYYVSGEANVSGEAIEAQALREQLQASLPEY 1030
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGL 459
M+P +++E +PL NGK+DR+GL
Sbjct: 1031 MVPAAYVKLERLPLTPNGKLDRRGL 1055
>UniRef50_A0UUS4 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 2752
Score = 229 bits (559), Expect = 3e-58
Identities = 168/543 (30%), Positives = 272/543 (50%), Gaps = 44/543 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I A++A KAG AY+P++P FP RI +ILKD++ +++ F + +P + +
Sbjct: 1774 ITAIMAVQKAGGAYLPVDPHFPAERIDYILKDSDTGILLTHKE-----FGDLKIP-QNIK 1827
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ + S E + +A TS++IA V+YTSGSTG PKG + + ++ NRL W +
Sbjct: 1828 KINLDLIDLSHGEKSNLPLIA--TSENIAYVIYTSGSTGKPKGTLIEHRSLVNRLNWMQK 1885
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+P + ++I + KT TF SV E++ + G + L +DP K+V NI
Sbjct: 1886 KYPLN-RDDIILQKTPYTFDVSVWELFWWSIAGAKVCFLEPGAEKDPGKIVEAIEKNNIT 1944
Query: 194 RLVLVPTLLRSILMYL-ALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+ VP++L L YL G SR + LK SGE L+ F + +LA
Sbjct: 1945 VIHFVPSMLGVFLEYLNQTGEVSR-VAGLKQVFASGEALTPSQVKAFRSLLSKNET-RLA 2002
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE DV+Y+ + D+LD +IPIG+P+DN + ++D+ + GE+ +
Sbjct: 2003 NLYGPTEATIDVSYFDCDTEDELD---SIPIGKPIDNTKLLIMDKNMQLQPVGVTGELCI 2059
Query: 313 AGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVK 369
G LA Y+ +F NP+ +P +RLYRTGD + G + Y GR D QVK
Sbjct: 2060 GGNCLAREYLNKPEMTDEKFIPNPY--KPN-ERLYRTGDLAKWRRDGNIEYLGRIDFQVK 2116
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG R++L E+E+ L P V +CVV+ + G+ ++ +V + + I+ L
Sbjct: 2117 IRGLRIELGEIEKQLTAHPDVKECVVVAWKKGEGDIHLVAYVVCENSMQAEQGGIQSFLE 2176
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
+L YM+P++ + +E +PL NGK+DR+ L +T D + +
Sbjct: 2177 KSLPDYMVPRIYVFLEMMPLSPNGKIDRKSLPAPVVST----DRAYEAPRNGTEKLLADI 2232
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
+G + F+E+GG+SL ++ TI L+ +G +EI D
Sbjct: 2233 WKKILSLDRIG------------INDNFFEIGGDSLKAMETIIHLKKQGMQLEIKDLFEG 2280
Query: 549 STL 551
T+
Sbjct: 2281 QTI 2283
>UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Stappia aggregata IAM 12614|Rep: Putative
non-ribosomal peptide synthetase - Stappia aggregata IAM
12614
Length = 4579
Score = 227 bits (556), Expect = 7e-58
Identities = 173/557 (31%), Positives = 270/557 (48%), Gaps = 46/557 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF- 78
++ LL KAGA Y+P++P++P+ R+T +L+DA+P L++ + S + A F
Sbjct: 106 VVCLLGVIKAGACYMPLDPAYPRQRLTDMLQDAQPDLILAEQSVAEIVAAADQTQQAVFL 165
Query: 79 --EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
L++E + P+ + L + + A ++YTSGSTG PKGV +A+ NRL W
Sbjct: 166 GSGALSREIAAQPETAPLGKDLLRGQSGNDPAYLVYTSGSTGRPKGVLGRQAALANRLLW 225
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN----- 191
P+++ E ++KT+L F+D E+ G L +G A+++ + DP++L
Sbjct: 226 IADALPFAEGER-TLFKTSLNFIDGSTELLGALCNGCAVVLAGGNVSADPRRLAEMVEAF 284
Query: 192 -IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
+ RL +VP+LL S+L L P L+ + WV SGE L L F D +
Sbjct: 285 AVTRLTVVPSLLASLLEDDCL-PG---LKGCRTWVTSGEPLPSSLLQRFCDKL--PDAW- 337
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L NFYG++E GD + + D IG P+ + +YLLD+ L P D E GE+
Sbjct: 338 LFNFYGASEAAGDSLW------ARCDAGWNTGIGNPIRDTRVYLLDDRLQPVTDGEKGEL 391
Query: 311 WVAGANLAAGY--VGGGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQ 367
+++G+ LA GY A RF +P P LYRTGD + G+ + GR+D Q
Sbjct: 392 YISGSGLALGYHRQPDKTAERFIASPFG--PAGALLYRTGDVARRMPDGSYEFLGRSDHQ 449
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VKIRG RV+ EV AL ++P V + V+ D G + +V GA +
Sbjct: 450 VKIRGVRVEPGEVAAALDRLPDVSRSAVVSNRRDNGEVYLAAYVVWGTGADRDGPKLMNA 509
Query: 428 LRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L AL +P ++ ++++PL NGK+DR L D E +V S
Sbjct: 510 LAEALPPAFLPSAIVSLDALPLTPNGKLDRAAL----------PDPEWSVG---SGASEP 556
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDF 545
+LG ++S++ F+ LGG+SL++ +LRDR G VE
Sbjct: 557 QSDLETLICEAFSELLGTR---SVSVQDNFFLLGGHSLSAARLAYRLRDRFGVEVEPRQI 613
Query: 546 LGASTLGEVLSKMSTDP 562
+ T E+ + P
Sbjct: 614 FDSPTPAELARLIGQAP 630
Score = 191 bits (466), Expect = 5e-47
Identities = 148/455 (32%), Positives = 229/455 (50%), Gaps = 36/455 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKES---GVPFA 76
I+ALLA K+GAAY+P++P +P RI +L+DA P LVI + + SM S +
Sbjct: 2240 IVALLAVLKSGAAYLPLDPDYPSARIAMMLEDAAPRLVISETATATSMTDGSPDLALLLL 2299
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ E + SA P +A+ + A V+YTSGSTG PKGV ++ + N +
Sbjct: 2300 DAQATGTELAAMSALSPTNADRRQAIHPAHPAYVIYTSGSTGKPKGVVVTREGLSNLAYA 2359
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL---VNIE 193
Q F S+ + + + +F + EI L+ G AL+I R+ DP L +N E
Sbjct: 2360 QIDRFAISEQSRVAQF-ASFSFDAAFSEIVTALVSGAALVIWPRQAFTDPAALKTFMNAE 2418
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
R+ + TL S+L ++ + L + V +GE +S E ++ D L N
Sbjct: 2419 RITHI-TLSPSLLSVMS----TTDLPDGCVLVTAGEAIS---VPEVRRW---SDRCCLVN 2467
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPT-----IPIGRPLDNCAIYLLDEELSPTRDSEPG 308
YG TEV + GS L L PT PIG P+ N +Y+LD+ L P + G
Sbjct: 2468 AYGPTEV-------TVCGSMSLPLTPTQEGDIAPIGLPIWNSGLYVLDQALQPVPNGVAG 2520
Query: 309 EVWVAGANLAAGY--VGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTD 365
E+++ G LA GY + ++RF +P A + R+YRTGD + G + + GR+D
Sbjct: 2521 ELYIGGVGLARGYQNLADLTSSRFVADPFAG--DGWRMYRTGDLVYRAEDGNLFFLGRSD 2578
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
AQVK+RG R++ E+ER L + V +C+V Y + ++ +V + G+ Q +
Sbjct: 2579 AQVKVRGRRIEPGEIERVLLERSDVAQCLVSVYSDRKATSRLVAYVIGQEGSEPDVQELL 2638
Query: 426 GKLRSALTHYMMPQVIE-VESIPLLVNGKVDRQGL 459
L YM+P I+ + +P L NGK+DR+ L
Sbjct: 2639 RYCADRLPDYMVPAQIDLLPYLPRLPNGKIDRKAL 2673
Score = 183 bits (445), Expect = 2e-44
Identities = 151/455 (33%), Positives = 229/455 (50%), Gaps = 39/455 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA K+GAAY+P++P +P RI +L+DA P LVI ++A + + GVP ++
Sbjct: 3783 IVALLAVLKSGAAYLPLDPDYPSARIAMMLEDASPRLVI-SETATAQVLTD-GVPTSALL 3840
Query: 80 ELAQEAT-----SHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
L +AT + SA P +A+ + A V+YTSGSTG PKGV ++ A+ N L
Sbjct: 3841 LLDAQATGTELAAMSALSPTNADRRQAIHPAHPAYVIYTSGSTGKPKGVVVTREALKNLL 3900
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL---VN 191
+ + + T + F + E++GPLL G A +L + R+ +L +
Sbjct: 3901 CCLSIEIRLRPQDRV-LSATTIGFDIAGLELYGPLLVG-ASALLFEGSQREADRLYDWIG 3958
Query: 192 IER---LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG 248
ER + P+L RS+ L +GP PL+ L GE L LA++ +
Sbjct: 3959 QERPTVMQATPSLWRSL---LEVGPLP-PLQIL----VGGEALDSGLAAQL------QTA 4004
Query: 249 YKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPG 308
+ N YG TE T + L S + T PIG+PL N +Y+LD L P D G
Sbjct: 4005 GPVTNVYGPTE----TTIWSLSASVSDEGSSTPPIGQPLWNSQVYVLDATLQPVADGVSG 4060
Query: 309 EVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTD 365
E+++ G LA GY G ++RF +P A R+YRTGD K G +++ GR D
Sbjct: 4061 ELYIGGLGLARGYHGRSDLTSDRFVADPFAGGG--ARMYRTGDMVYRQKTGELVFLGRGD 4118
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
+QVKIRGHR++ E+E A+ + + + VV+ ++ +V GA +
Sbjct: 4119 SQVKIRGHRIEPGEIEAAITSMTNIAQAVVVDRPDGVRGSSLVAYVVPVEGAELKTDALR 4178
Query: 426 GKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L L YM+P + + +PL NGK++RQ L
Sbjct: 4179 SVLLRNLPDYMVPGAFVVLPELPLTPNGKLNRQAL 4213
Score = 173 bits (421), Expect = 2e-41
Identities = 150/563 (26%), Positives = 245/563 (43%), Gaps = 45/563 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LA KAG AYVP+ + P R+ +++D + LV+ D+ D VP +
Sbjct: 1177 VVVTLAIVKAGGAYVPLNRNDPPNRLQQLVEDTKTHLVL-TDAEDAISITFDDVPCVPYC 1235
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL QEA+ + E+L + + IA VL+TSGSTG PKG+ +S+ I +
Sbjct: 1236 EL-QEASEN--------ESLPNVAAGQIACVLFTSGSTGRPKGIAISHRNI--QALALDG 1284
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVLV 198
+P E + + + F S EIW PL+ G+ L + + D + + +E +
Sbjct: 1285 CWPEGSHERVLL-HSPYAFDASTYEIWTPLMRGQELFV-APPGILDAETIARLVEERHVT 1342
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + L + G + L+ + GE S E + + N YG
Sbjct: 1343 AACITTRLFNIIAGEKPEAFKPLRSVLIGGEAASAEALR---RATAASPDTRFVNGYGPA 1399
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E VT++ + ++ +PIG P DNC++ +LD+ L P GE+++AG L
Sbjct: 1400 EGTTFVTWHAMRTLEESA--HKVPIGLPRDNCSVRILDDRLQPVGIGMVGELYLAGDCLT 1457
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHRV 375
GY+G G A RF +P P R+YRTGD G + + GR D QVKI G R+
Sbjct: 1458 LGYLGRTGLTAERFVADPAG--PAGSRMYRTGDLVRWRSDGLLTFVGRADHQVKINGFRI 1515
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+ E+E A+ + P + +C V+ G +++ +V + + +L L +
Sbjct: 1516 EPQEIENAIGRQPDIGQCTVVVREDRPGEKKLVAYVVGAGAGEPDLERLRERLSETLPAF 1575
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P + +E +P NGK+D + L A +I
Sbjct: 1576 MVPAHFVLLEHLPFTTNGKLDVKRL--------------PAPEIHSDRAIAPVGQTELDI 1621
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEV 554
VLG T+ F+ LGG+S+ SI +++ R G D T E+
Sbjct: 1622 CALFAEVLGLE---TVGSADNFFALGGDSILSIQLVSRARRAGLVFSAKDVFSNKTPAEL 1678
Query: 555 --LSKMSTDPNGGADSKEATFTA 575
+++ P G D KE +A
Sbjct: 1679 ATVAQRQQLPEAGTDLKEGWISA 1701
>UniRef50_A6ASZ6 Cluster: Enterobactin synthetase component F; n=2;
Vibrio harveyi|Rep: Enterobactin synthetase component F
- Vibrio harveyi HY01
Length = 1315
Score = 227 bits (555), Expect = 9e-58
Identities = 159/455 (34%), Positives = 241/455 (52%), Gaps = 34/455 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ A AGA YVP++P +P+GRI ++L + P V + + + V +
Sbjct: 528 IVVQQAILAAGAVYVPVDPDYPEGRIHYMLDSSAPQFVFSTSALQDKLPQGVEVKLVDDD 587
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L T + EP+ + S A ++YTSGSTG PKGV +++ AI NRL W
Sbjct: 588 TLP---TIYKRVEPLPPQVKPEPYSP--AYMIYTSGSTGKPKGVVVTHDAIVNRLLWMHD 642
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIERLV 196
+P + + + + KT F SV E + P++ G L+I + +DP Q L++ E++
Sbjct: 643 QYPITAKDRV-LQKTPAGFDVSVWEFFWPMMVGSCLVIAKPDGHKDPIYLQDLIHREKIT 701
Query: 197 ---LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VP++L+ I + A + LR++ CSGE L EL + +++ F L N
Sbjct: 702 TLHFVPSMLQ-IFVQQADPDLCQSLRQV---FCSGEALPIELVNHYYQAFNAS----LHN 753
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVTY+ E + + +IPIGRP+ N IY+LD+ L+P G +++A
Sbjct: 754 LYGPTEAAVDVTYWPSEANTE---GTSIPIGRPVWNTQIYILDDALNPVPPGVVGHLYIA 810
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKI 370
G LA GY G A RF DNP P+ R+Y +GD + GA+ Y GR+D QVKI
Sbjct: 811 GRQLAQGYYGQPELTAERFIDNPFG--PQGSRMYLSGDLARWREDGAIEYCGRSDFQVKI 868
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT---TKPGARTSAQHIEGK 427
RG R++L E+E ALA P V + VL + G+ ++ +VT T+ G ++A ++
Sbjct: 869 RGFRIELEEIENALANHPSVAQVAVLAQEYNDGDKRLVAYVTAENTEQGIDSNA--LQTY 926
Query: 428 LRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLK 461
L L YM+P +E+E+ PL NGK+DR L K
Sbjct: 927 LAEPLPEYMVPSYFVELEAFPLTPNGKLDRSALPK 961
>UniRef50_A3P7D7 Cluster: Syringomycin synthetase; n=37;
Burkholderia|Rep: Syringomycin synthetase - Burkholderia
pseudomallei (strain 1106a)
Length = 3348
Score = 227 bits (555), Expect = 9e-58
Identities = 174/551 (31%), Positives = 260/551 (47%), Gaps = 35/551 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDD-SADPSMFKESGVPFASF 78
++ LLA KAG AYVP++PS P R+ +L D P V+ DD AD ES V S
Sbjct: 619 VVGLLAILKAGGAYVPLDPSHPPERLRRMLDDTNPVAVLVDDIGADALASFESHVAARSP 678
Query: 79 E-ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
L+++ A P + T + +A V+YTSGS+G PKGV + + NRLWW
Sbjct: 679 RVHLSRDIAQWRACSPANPPTPRERAARRLAYVIYTSGSSGEPKGVMNEHRGVVNRLWWM 738
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIER 194
+T+ D + + KT +F SV E + PL+ G L+I E +DP +L++ ER
Sbjct: 739 QQTYAL-DERDAVLQKTPFSFDVSVWEFFWPLMSGARLVIAKPEGHKDPAYLSELIDRER 797
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ + + + +L A+R +K +CSGE L L F++ + +L N
Sbjct: 798 VTTLHFVPSMLQAFLEDEGAARGCGSVKRVMCSGEALPPSLVKRFYRCLPDA---RLHNL 854
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE DVT + + + ++PIG P+ N IY+LD P GE+++ G
Sbjct: 855 YGPTEAAVDVTAWACDAEEG---GASVPIGWPIANTRIYVLDGHGQPVPRGVAGELYIGG 911
Query: 315 ANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
+A GY+ RF D+P RLY+TGD G++ Y GR D QVKIR
Sbjct: 912 VQVARGYLNRPELTRERFVDDPFVAG---GRLYKTGDLARWRTDGSLEYLGRNDFQVKIR 968
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E LA+V GV + VVL D G+P + + +
Sbjct: 969 GFRIELGEIEAQLAKVAGVRETVVL--ARDSGSPAGEKRLVAYYTGNADVAALREQATRH 1026
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L YM+P + +++ PL NGK+DR+ L DDA + +
Sbjct: 1027 LPAYMVPSAYVRLDAWPLTPNGKLDRRAL------PAPADDAYARAEYEAP------QGA 1074
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
+ L R +S F+ELGG+SL I KLR G + ++ AST
Sbjct: 1075 KEEALAAIWKDLLPVER--ISRHDNFFELGGHSLLVIGLSEKLRAAGLHADVRVVYRAST 1132
Query: 551 LGEVLSKMSTD 561
L ++ + + TD
Sbjct: 1133 LADLAAHLGTD 1143
Score = 215 bits (525), Expect = 4e-54
Identities = 171/560 (30%), Positives = 259/560 (46%), Gaps = 53/560 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDD-SADPSMFKESGVPFASF 78
++ LLA KAG AYVP++PS P R+ +L D P V+ DD AD ES V S
Sbjct: 2780 VVGLLAILKAGGAYVPLDPSHPPERLRRMLDDTNPVAVLVDDIGADALASFESHVAARSP 2839
Query: 79 E-ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
L+++ A P + T + +A V+YTSGS+G PKGV + + NRLWW
Sbjct: 2840 RVHLSRDIAQWRACSPANPSTPRERAARRLAYVIYTSGSSGEPKGVMNEHRGVVNRLWWM 2899
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIER 194
+T+ D + + KT +F SV E + PL+ G L+I E +DP +L++ ER
Sbjct: 2900 QQTYAL-DERDAVLQKTPFSFDVSVWEFFWPLMSGARLVIAKPEGHKDPAYLSELIDRER 2958
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ + + + +L A+R +K +CSGE L L F++ + +L N
Sbjct: 2959 VTTLHFVPSMLQAFLEDEGAARGCGSVKRVMCSGEALPPSLVKRFYRCLPDA---RLHNL 3015
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE DVT + + + ++PIGRP+ N IY+LDE P GE+++ G
Sbjct: 3016 YGPTEAAVDVTAWACDAEEG---GASVPIGRPIANTRIYVLDEYGQPVPRGVAGELYIGG 3072
Query: 315 ANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
+A GY+ RF D+P RLY+TGD G++ Y GR D QVKIR
Sbjct: 3073 VQVARGYLNRPELTRERFVDDPFVAG---GRLYKTGDLARWRTDGSLEYLGRNDFQVKIR 3129
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLC----------------YGLDRGNPEILGFVTTKP 415
G R++L E+E LA+V GV + VVL + G ++ + T
Sbjct: 3130 GFRIELGEIEAQLAKVAGVRETVVLAREAAPDTKRHAASNENSASNSGEKRLVAYYT--- 3186
Query: 416 GARTSAQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEV 474
A + + L YM+P + +++ PL NGK+DR L DDA
Sbjct: 3187 -GDADATALRAQAAQHLPSYMVPSAYVRLDAWPLTPNGKLDRHTL------PAPADDAYA 3239
Query: 475 AVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR 534
+ + + L R +S F+ELGG+SL +I I +R
Sbjct: 3240 RAEYEAP------QGAKEEALAAIWKDLLPVER--ISRHDNFFELGGHSLLAITLIEHMR 3291
Query: 535 DRGYYVEISDFLGASTLGEV 554
+ +++ A TL ++
Sbjct: 3292 RANLHADVTTLFTAPTLADL 3311
Score = 166 bits (403), Expect = 2e-39
Identities = 165/559 (29%), Positives = 251/559 (44%), Gaps = 57/559 (10%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELA 82
LLA KAG AYVP++P + R+ IL D+ P++V+ D + ++ +G P +L
Sbjct: 1708 LLAILKAGGAYVPLDPGYASERLRAILDDSRPAIVLADAAGRTALDALAGAP--PIADLH 1765
Query: 83 QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFP 142
+A+ SA P + LT +A V+YTSGSTG PKGV + ++++ N LW
Sbjct: 1766 ADASRWSA-LPSTPPRVEGLTPRHLAYVIYTSGSTGQPKGVMVEHASVVN-LWRALDEAI 1823
Query: 143 YS--DSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERL-V 196
Y S ++ F DS+ + W LL GR L+++ D ++L++ +R+ V
Sbjct: 1824 YRAHPSARRVSLNASIAF-DSLVKQWVQLLSGRTLVVVPEPVRFDGRRLLDAIGRDRIDV 1882
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
T + L+ A GP ++ L GE + K + SE + N YG
Sbjct: 1883 FDCTPSQLALIEGARGPEDEAYPQVTL--VGGEAIGKGMWSEL----ASASSRTYYNVYG 1936
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE D T + IG PL N Y+L+E LSP GE+++ GA
Sbjct: 1937 PTECTVDATLARITAEHAPH------IGGPLANVRAYVLNERLSPAPVGVRGELYIGGAG 1990
Query: 317 LAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
+A GY+ R F D+P RLYRTGD G++ Y GR D QVKIRG
Sbjct: 1991 VARGYLNRPELTRERFIDDPFVAGG---RLYRTGDLARWRTDGSLEYLGRNDFQVKIRGF 2047
Query: 374 RVDLLEVERALAQVPGVDKCVVLC--YGLDRG-NPEILGFVTTKPGARTSAQHIEG---- 426
R++L E+E LA+V GV + VVL D N ++ T + + G
Sbjct: 2048 RIELGEIEAQLAKVTGVREVVVLARDSAADTDQNADLNASATANSSEKRLVAYYTGDADV 2107
Query: 427 -KLRSA----LTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDC 480
LR+ L YM+P + +++ PL NGK+DR+ L DDA + +
Sbjct: 2108 VALRAQAAQHLPSYMVPSAYVRLDAWPLTPNGKLDRRAL------PAPADDAYARAEYEA 2161
Query: 481 SXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYY 539
+ L R +S F+ELGG+SL ++ +++LR
Sbjct: 2162 P------QGAKEEALAAIWRELLHVER--VSRHDNFFELGGHSLLAVQLVSRLRQALSVE 2213
Query: 540 VEISDFLGASTLGEVLSKM 558
V +S A L + ++
Sbjct: 2214 VALSTVFDAPVLSALAERL 2232
>UniRef50_Q7NVV9 Cluster: Synthetase CbsF; n=3; cellular
organisms|Rep: Synthetase CbsF - Chromobacterium
violaceum
Length = 2859
Score = 224 bits (547), Expect = 8e-57
Identities = 162/460 (35%), Positives = 241/460 (52%), Gaps = 42/460 (9%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+AL+A +AGAAY+P++ +P R+ +++ DA+P+L++ P F G +E
Sbjct: 2076 LALMAAQEAGAAYLPLDTGYPDERLAYMVADAKPALIVTCAELAPR-FAAMGTLLLQ-DE 2133
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
LA E + DA L P D A +LYTSGSTG PKGV +S+ AI NRL W
Sbjct: 2134 LAAEP------QAFDAPALTP---DHAAYLLYTSGSTGRPKGVLVSHRAIVNRLLWMQHE 2184
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIER 194
+ ++++ + KT +F SV E + PL+ G L + + RDP+ L+ +
Sbjct: 2185 YGLG-ADDVVLQKTPCSFDVSVWEFFWPLIVGAKLFMAPPDAHRDPEALLELIAARGVTT 2243
Query: 195 LVLVPTLLRSILMYLALGPASRPLR--RLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L VP++L ++L ++ A+R + L+ CSGE LS+ELA Y G D L
Sbjct: 2244 LHFVPSMLAALLAHMQGDAAARSAQTASLRRVFCSGEALSRELAD---GYAGLIDA-PLH 2299
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE DV+Y + ++PIG P+ N A+ +LD L P PGE+++
Sbjct: 2300 NLYGPTEAAVDVSYQ--PAAKPAPESASVPIGLPVWNTALRILDVALRPVPVGAPGELYL 2357
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
G LA GY+G A+RF +P+A + +R+YRTGD L+ G V Y GR D Q+K
Sbjct: 2358 CGVQLAHGYLGRPDLTASRFIADPYA---DGERMYRTGDIARWLLDGVVEYLGRCDDQLK 2414
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVV--------LCYGLDRGNPEILGFV-TTKPGARTS 420
IRG RV+L E+E AL PGV + VV + N +++G+V + P
Sbjct: 2415 IRGQRVELGEIEAALLSQPGVARAVVHARALGGQAAHAAGADNRQLVGYVIASDPDNPPD 2474
Query: 421 AQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
A + L L +M+P V+ + PL NGK+DR+ L
Sbjct: 2475 ADTLRAALAKVLPAHMVPVAVMRLADFPLSANGKLDRKAL 2514
Score = 166 bits (404), Expect = 2e-39
Identities = 161/582 (27%), Positives = 258/582 (44%), Gaps = 58/582 (9%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T++++L T AGAA++P++ +P R+ + +DA P+L++ + +
Sbjct: 555 TVVSILGTLAAGAAFLPLDLDYPPERLAMMCEDAAPALLLTRSDVCGRLPDLPALCLDDG 614
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ- 137
E A+ A + SA DAE L PL D +A ++YTSGSTG PKGV +++++ N L Q
Sbjct: 615 EVRARLA-ARSAQPLDDAERLRPLNGDRLAYMIYTSGSTGKPKGVMIAHASFLNLLLSQQ 673
Query: 138 ---FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--- 191
F F + +TA D E LL G+ + + E RD Q+LV
Sbjct: 674 TGLFGDFVRGRGRRVRTMQTASLSFDGALEQLFWLLMGQEVHLCDEELRRDAQQLVELVR 733
Query: 192 ---IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG 248
I+ + + P+LLR +L G + + + GE + L E Y
Sbjct: 734 RERIDEMDVPPSLLRQML---DCGLMDDGHWQPGMVMVGGEAVPPALWKEMRGY----TQ 786
Query: 249 YKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPG 308
NFYG TE T L + P + GRP+ N +LD L P G
Sbjct: 787 LHFHNFYGPTEY----TISALGAPGTIAEEPVV--GRPVANTRALVLDAALRPVAIGVAG 840
Query: 309 EVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTD 365
E+++AG L GY+ A+RF +P + + +YRTGD G + + GR D
Sbjct: 841 ELYLAGDGLGLGYLNRPSLTASRFVASPFG---DGELMYRTGDLVRWNAHGQMDFIGRVD 897
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
Q+K+RG R+++ EVE ALA +PGV+ V L + G+ ++ + T R +
Sbjct: 898 HQIKVRGFRIEMGEVEHALASLPGVNAAVALAEAVG-GSHRLIAYCTMAEAGRHEEAGLS 956
Query: 426 ----GKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL--LKMYENTNNNDDAEVAVDI 478
+L L YM+P + V P+ +NGK+DR+ L ++ + + A A +
Sbjct: 957 AALLAQLAETLPDYMVPSALAVLPEWPVNINGKIDRKALPAIRPQNAASGREPANEAERL 1016
Query: 479 DCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGY 538
C+ V VL G F++LGG+S++++ T+LR G+
Sbjct: 1017 LCA---------------AVARVLNLEQTGP---DDDFFQLGGDSISAMSLGTELRRAGF 1058
Query: 539 YVEISDFLGASTLGEVLS--KMSTDPNGGADSKEATFTAVPM 578
+ D T + + K N AD K +P+
Sbjct: 1059 LLRPRDVFAKRTPAGMAAALKPLAAANPAADDKAGPVGKLPI 1100
>UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospira
multiformis ATCC 25196|Rep: Amino acid adenylation -
Nitrosospira multiformis (strain ATCC 25196 / NCIMB
11849)
Length = 4037
Score = 224 bits (547), Expect = 8e-57
Identities = 175/557 (31%), Positives = 266/557 (47%), Gaps = 53/557 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLAT KAG AYVP++P +PQ R+ +++ D+ L++ + P +
Sbjct: 2117 VVGLLATLKAGGAYVPLDPEYPQERLAYMVADSGIGLLLTQSGVRSRIPHSGQYPVLELD 2176
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L E DE D+ A L ++A V+YTSGSTG PKG + A+ NRL W
Sbjct: 2177 RLDLE------DE-SDSNPQAVLHGHNLAYVIYTSGSTGKPKGAGNRHLALYNRLAWMQE 2229
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+ + + + + KT +F SV E + PL++G L I + RDP +L+ N+
Sbjct: 2230 AYELGNDDTV-LQKTPFSFDVSVWEFFWPLMYGARLAIAAPGDHRDPARLLSLILRQNVT 2288
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L++ L + + LRR+ +CSGE L E+ + F+ G L N
Sbjct: 2289 TLHFVPSMLQAFLAHEGIEACVATLRRI---ICSGEALQAEVQKQVFRKL---PGVGLFN 2342
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT + E D D ++PIG+P+ Y+LD L+ GE+++
Sbjct: 2343 LYGPTEAAIDVTQW--ECVDDRD--NSVPIGKPISGLQAYILDVHLNQVPQGVAGELYLG 2398
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY+ GG A+RF +P RLYRTGD G + Y GR D QVKI
Sbjct: 2399 GIGLARGYLNRGGLTADRFIADPF--DETGGRLYRTGDLARWRSDGQIEYLGRLDHQVKI 2456
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLC-YGLDRGNP----EILGFVTTKPGARTSAQHIE 425
RG R++L E+E L P V + VV+ G + NP ++ +V+ A +
Sbjct: 2457 RGFRIELGEIETQLLAQPEVREAVVVAREGSNASNPTGGARLIAYVSAHATTDLDAARLR 2516
Query: 426 GKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLK-MYENTNNNDDAEVAVDIDCSXX 483
L L YM+P +I V ES+PL +GKVDR+ L + + +T + + + +
Sbjct: 2517 EALARTLPDYMLPSMIVVLESLPLNPSGKVDRKALPEPEFTHTEHYEAPQGEAE------ 2570
Query: 484 XXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEIS 543
G VLG A G F+ELGG+S+ S+ +T+ R G+ +
Sbjct: 2571 --------EVLAGIWGQVLGVAQVGR---HDNFFELGGDSILSLQIVTRARRVGWKITPR 2619
Query: 544 DFLGASTLGEVLSKMST 560
T+ + T
Sbjct: 2620 QLFERQTIASLAEVAET 2636
Score = 166 bits (403), Expect = 2e-39
Identities = 157/536 (29%), Positives = 250/536 (46%), Gaps = 49/536 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLAT KAG AYVP++P +PQ R+ +++ D+ L++ + P +
Sbjct: 580 VVGLLATLKAGGAYVPLDPEYPQERLAYMVADSGIGLLLTQSRVRSRIPHSGQYPVLELD 639
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L E DE D+ A L ++A V+YTSGSTG PKGV +++ + + +
Sbjct: 640 RLDLE------DE-SDSNPQAVLHGHNLAYVIYTSGSTGKPKGVSVTHEPLSMHVQSIGK 692
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRETTRDPQKLVNI-ERLVL 197
+ + + + ++ F D E W PL G AL+ + + + I + +
Sbjct: 693 AYGMTTMDRELQF-ASINF-DGAHERWLVPLAFGSALMPRDNDFWSVERTVAEIVKHRIT 750
Query: 198 VPTLLRSILMYLA--LGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + L +A LG A R L ++ + GE +S+ AS F + ++ N Y
Sbjct: 751 IACFTPNYLHQMAELLGTAGRAL-PIRSYTVGGEAMSR--ASFDFVQTTLQPP-RIINGY 806
Query: 256 GSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
G TE V+ + G+ Y +PIG P+ + Y+LD +L+P GE+++ G
Sbjct: 807 GPTETVITPLISKAYPGTGFESAY--MPIGCPVGDRIAYILDSDLNPVPAGVAGELYLGG 864
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
LA GY+ GG A+RF +P RLYRTGD G + Y GR D QVKIR
Sbjct: 865 IGLARGYLNRGGLTADRFIADPF--DETGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIR 922
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLC-YGLDRGNP----EILGFVTTKPGARTSAQHIEG 426
G R++L E+E L P V + VV+ G NP ++ +V+ A +
Sbjct: 923 GFRIELGEIETQLLAQPEVREAVVVAREGSSASNPTGGARLIAYVSAHATTDLDAARLRE 982
Query: 427 KLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLK-MYENTNNNDDAEVAVDIDCSXXX 484
L L YM+P +I V ES+PL +GKVDR+ L + + +T + + + +
Sbjct: 983 ALARTLPDYMLPSMIVVLESLPLNPSGKVDRKALPEPEFTHTEHYEAPQGEAE------- 1035
Query: 485 XXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYV 540
G VLG A G F+ELGG+S+ S+ +T+ R G+ +
Sbjct: 1036 -------EVLAGIWGQVLGVAEVGR---HDNFFELGGDSILSLQIVTRARRAGWKI 1081
Score = 157 bits (381), Expect = 1e-36
Identities = 140/461 (30%), Positives = 212/461 (45%), Gaps = 41/461 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LLA KAG AYVP++P +P R++ ++ D+ SL++ ++ + GV +
Sbjct: 3197 IVTLLAVLKAGGAYVPLDPEYPVERLSFMVNDSGMSLLLTEEKLLAKLGSGFGVQVWLLD 3256
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + T+ S P PL ++A ++YTSGSTG+PKGV +++ + + Q
Sbjct: 3257 SL--DLTAESGSNPD-----IPLHEHNLAYIIYTSGSTGLPKGVAVAHGPL--SMHCQAT 3307
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIW------GPLLHGRALLILSRETTRDPQKLVNIE 193
Y + C D E W G L R + + E T D I
Sbjct: 3308 AGIYGMTPHSCELLFMSFSFDGAHERWLTALTVGAGLAVRDQELWTAEQTYDALHSYGIT 3367
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
P L + + A P S P ++L+V GE + K K L N
Sbjct: 3368 NAAFPPAYLGQVAEWAA--PRSDP-PPVELYVFGGEAMPKASYDLVRKTLRPR---ILIN 3421
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + + E S+ D PIGRP+ Y+LD ++ P GE+++
Sbjct: 3422 GYGPTETVVTPLIWKTEASNSFDC-AYAPIGRPVGERTAYVLDLDMQPVPIGRVGELYIG 3480
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKI 370
G LA GY+G G A RF +P RLYRTGD L G + Y GR D QVKI
Sbjct: 3481 GYGLARGYLGRAGLTAERFVADPF--DGNGGRLYRTGDLVRWLDDGNIEYIGRADHQVKI 3538
Query: 371 RGHRVDLLEVERALAQVPGV-DKCVVLCYGLDRGNPEILGFVTTK-------PGARTSA- 421
RG R++L E+E + ++ G+ D VV+ G G P++ +V K P + SA
Sbjct: 3539 RGFRIELGEIEACIRELTGLTDVAVVVREG--AGGPQLAAYVAPKETTGMVAPVRKGSAG 3596
Query: 422 --QHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
++ +L L YM+P ++ ++ +P L +GK+DR L
Sbjct: 3597 LGSTLKQQLVRRLPEYMVPAHIVILDKLPRLPSGKLDRSAL 3637
>UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia
rhizoxina|Rep: RhiB protein - Burkholderia rhizoxina
Length = 6722
Score = 223 bits (546), Expect = 1e-56
Identities = 158/451 (35%), Positives = 237/451 (52%), Gaps = 33/451 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA KAG AY+P++P +P R+ I+ DA ++++ + G +
Sbjct: 8 IIALLAIMKAGGAYLPLDPGYPDERLALIIDDAAVTVLLTQQRFRSRLAGYDGEVLC-LD 66
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ Q+A DE P D +A ++YTSGSTG PKG L + AICNRL W R
Sbjct: 67 DANQQALF--GDEANPVPINGP---DDLAYIIYTSGSTGRPKGCMLPHKAICNRLLWMQR 121
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLV 196
+ ++ I + KT TF SV E++ PLL G L++ E +D LV + E++
Sbjct: 122 HYEVGAADRI-LQKTPFTFDVSVWELFLPLLSGACLVMAKPEGHKDAHYLVEVIQAEQIT 180
Query: 197 L---VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP++LR L + A+ S + K++V SGE L+ +L +F + E L N
Sbjct: 181 ICHFVPSMLRFFLKHPAV---SECISLQKVFV-SGEALTHDLLLQFRQLLSAE----LHN 232
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVTY+ G + D +PIGRP+DN IY+LD E P E GE+ +
Sbjct: 233 LYGPTEAAVDVTYW--RGEPRED--QLVPIGRPIDNIQIYILDSEAKPVPIGETGELCIG 288
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY+ A +F +P + + RLYRTGD L G + GR D+QVK+
Sbjct: 289 GLGLARGYLNRPELTAEKFIRDPFSGEAG-ARLYRTGDKARFLSNGEIELLGRFDSQVKL 347
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E AL P +D VL +P+++ FV + G A + +++
Sbjct: 348 RGFRIELGEIESALKSHPAIDDAAVLVKDPGSADPKLVAFVVAQ-GLDKKA--VRDFIKA 404
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGLL 460
L YM+P ++ ++ IP+ +GK DR+ LL
Sbjct: 405 RLPEYMVPNLVSFIDQIPVTAHGKADRKALL 435
>UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1;
Alcanivorax borkumensis SK2|Rep: Peptide synthetase,
putative - Alcanivorax borkumensis (strain SK2 / ATCC
700651 / DSM 11573)
Length = 3600
Score = 223 bits (544), Expect = 2e-56
Identities = 157/446 (35%), Positives = 233/446 (52%), Gaps = 29/446 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA +AG AYVP++PS+PQ R+++IL+ + P+L++ S K VP +
Sbjct: 3067 VIGILAITRAGGAYVPLDPSYPQDRLSYILEASSPALLLTHSSLLGGWPK--AVPMWCLD 3124
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL +D+P + D V+YTSGSTG PKGV + +A+ NRL W
Sbjct: 3125 EL------DVSDQPTTPPPVQ-WHPDQAVYVIYTSGSTGKPKGVLNTQAALENRLLWMQN 3177
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+P ++ + + KT +F SV E + PL+ G L + + DPQ L + V
Sbjct: 3178 EYPLQAADCV-LQKTPFSFDVSVWEFFWPLMVGARLAVAPPQAHGDPQWLQQVMADEGVT 3236
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL + S+L + + RLK +CSGE L EL F + D +L N YG
Sbjct: 3237 TLHFVPSMLKAFVDASGLQNVPRLKRLICSGEALDMELQKAVFT---SRDDVELHNLYGP 3293
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DV+++ + T+PIG P+ N +Y+LD +L+P PGE+++AG L
Sbjct: 3294 TEAAIDVSFWQCQPEGG----HTVPIGAPISNIQLYVLDTDLNPVPRGVPGELYLAGIGL 3349
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHR 374
A GY G A RF NP+ R+YRTGD G + Y GR D QVKIRG R
Sbjct: 3350 ARGYFGRSDLTAERFVPNPYGDAG--SRMYRTGDQVRQRGDGIIEYLGRLDHQVKIRGLR 3407
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E+ L Q+P V+ VV+ D G+ +++ +V+ R Q L AL
Sbjct: 3408 IELGEIEQQLKQLPDVNDAVVVADHSDTGD-QLVAYVSADSDNREVWQQ---ALADALPE 3463
Query: 435 YMMPQVIEV-ESIPLLVNGKVDRQGL 459
YM+P + V E++PL NGK+DR+ L
Sbjct: 3464 YMVPALFMVLEALPLSPNGKLDRKAL 3489
Score = 143 bits (346), Expect = 2e-32
Identities = 128/452 (28%), Positives = 218/452 (48%), Gaps = 34/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A +A KAG A++P++P +P+ R+ ++LKD+ L++ SA + E A+
Sbjct: 2015 VEAFIAVMKAGGAFLPLDPGYPKDRLHYMLKDSGARLLL-TSSALIGVLPE----VATVA 2069
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+A + S + D P +A P D +A V+YTSGSTG PKGV L+++ + + +
Sbjct: 2070 PVAVDRLSLN-DFPANALNNEP-HPDQLAYVIYTSGSTGKPKGVSLTHAGLSMHVQTIGK 2127
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWG-PLLHGRALLIL-----SRETTRDPQKLVNIE 193
+ + +++ + +++F D E W PL G ++I S + T D + +
Sbjct: 2128 RYGMTP-DDVELQFASISF-DGAVERWTVPLAFGSRVVIRDQQLWSAQQTCDALQKEGVT 2185
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ P+ + +L ++ +P ++ W GE ++E + + ++ N
Sbjct: 2186 IACIPPSYMGPLLDWIE---QEKPPLNVRSWTLGGEAFTRETFERMQQVLKPQ---RILN 2239
Query: 254 FYGSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE V+ + + EG Y PIG + +Y+LD++L+ GE+++
Sbjct: 2240 GYGPTETVVTPMLWAAYEGDTLSSAYA--PIGHAVGPRKLYVLDQDLNRVPVGVAGELYI 2297
Query: 313 AG-ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQV 368
LA GY A RF +P E R+YRTGD V+ Y GR D QV
Sbjct: 2298 GNEVGLARGYHQRPDLTAERFLPDPFGEPGE--RMYRTGDLVKYRDDGVMEYLGRVDQQV 2355
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG R++L E+E L P V + VVL G ++G++ P S + L
Sbjct: 2356 KIRGFRIELGEIESRLLAHPQVREAVVLAQP-SPGGDRLVGYLV--PRGPLSTDALIATL 2412
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+L YM+P ++ +E++PL GKV+R+ L
Sbjct: 2413 AESLPDYMVPSHLLTLEAMPLTPAGKVNRKAL 2444
Score = 134 bits (325), Expect = 7e-30
Identities = 125/462 (27%), Positives = 219/462 (47%), Gaps = 47/462 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A +A KAG A++P++P +P R+ ++L+D+ SL++ ++ V + +
Sbjct: 534 VEAFIAVMKAGGAFLPLDPGYPADRLRYMLEDSGASLLLTSSDLVDTLPSVEAVNPIAVD 593
Query: 80 ELAQEATSHSA--DEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
EL+ + ++ +EP D +A V+YTSGSTG PKGV L+++ + +
Sbjct: 594 ELSLDDFAYGILNEEP---------HPDQLAYVIYTSGSTGKPKGVSLTHAGLSMHVQTI 644
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWG-PLLHGRALLI-----LSRETTRDPQKLVN 191
+ + +++ + +++F D E W PL G ++I S E + +
Sbjct: 645 GERYGMT-PDDVELQFASISF-DGAVERWTVPLAFGSRVVIRDQALWSAEKCCEVLQEEG 702
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ P+ + +L ++ +P +++ W GE ++E + + ++
Sbjct: 703 VTIACFPPSYVGPLLDWI---EQEKPPLKVRSWTLGGEAFTRETFERMQQVLKPQ---RI 756
Query: 252 ANFYGSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
N YG TE V+ + + EG Y PIG + +Y+LD++L+ GE+
Sbjct: 757 LNGYGPTETVVTPMLWAAYEGDTLSSAY--APIGHAVGPRKLYVLDQDLNRVPVGVAGEL 814
Query: 311 WVAG-ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK----GAVLYAGR 363
++ LA GY A RF +P E R+YRTGD LVK G + Y GR
Sbjct: 815 YIGNEVGLARGYHQRPDLTAERFLPDPFGEPGE--RMYRTGD---LVKYRDDGVMEYLGR 869
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART---- 419
D QVKIRG R++L E+E L + + V+ G+ ++G++ + A +
Sbjct: 870 VDQQVKIRGFRIELGEIESQLLGHEQIREAAVVAQPSPTGD-RLVGYIVMRNAAHSVPRE 928
Query: 420 -SAQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
Q I L +L YM+P Q+I +E++PL GKVDR+ L
Sbjct: 929 HDPQTILAALSESLPDYMVPSQLITLEAMPLTPAGKVDRKAL 970
>UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin
synthetase C-related non- ribosomal peptide synthetase
module; n=8; Proteobacteria|Rep: Arthrofactin
synthetase/syringopeptin synthetase C-related non-
ribosomal peptide synthetase module - Bradyrhizobium sp.
(strain BTAi1 / ATCC BAA-1182)
Length = 8646
Score = 223 bits (544), Expect = 2e-56
Identities = 156/458 (34%), Positives = 231/458 (50%), Gaps = 36/458 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM------FKESGV 73
I+ LLA KAG AYVP++P++P R+ +L+D+ P ++ SA ++ SGV
Sbjct: 7018 IVGLLAILKAGGAYVPLDPAYPPERLAFMLQDSAPVALLVGGSAQAALSVVEAELAASGV 7077
Query: 74 PFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
P A + A P +E LT D +A V+YTSGSTG PKG + A+ NR
Sbjct: 7078 PVLDIGADAAQWAEAPARNPARSEV--GLTPDHLAYVIYTSGSTGTPKGAMNGHRAVVNR 7135
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
L W + D + + KT +F SV E + PLL G L++ E +DP LV +
Sbjct: 7136 LLWMQDAYAL-DGGDAVLQKTPFSFDVSVWEFFWPLLAGARLVMARPEGHKDPAYLVEVI 7194
Query: 194 R------LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
R L VP++L+ + Y G + +K +CSGE LS LA+ + +
Sbjct: 7195 RRERITTLHFVPSMLQIFVEYAEAGSCT----SVKRVMCSGEALSPVLAARLLERL---E 7247
Query: 248 GYKLANFYGSTEVMGDVTYY--VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDS 305
G +L N YG TE DVT + E SD ++PIGRP+ N IY+LD+ P
Sbjct: 7248 GTELHNLYGPTEAAVDVTAWRCAKEASD-----ASVPIGRPISNTQIYILDQHGDPVPIG 7302
Query: 306 EPGEVWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAG 362
GE+ + G + GY+ A RF ++ + + RLYRTGD G L G + Y G
Sbjct: 7303 VAGEIHIGGVQVGRGYLNRPELTAERFVEDRFSGEAG-ARLYRTGDLGRWLEDGTIAYLG 7361
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R D QVKIRG R++L E+E L++ V V+ G+ ++ + + A A+
Sbjct: 7362 RNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIAREDVAGDKRLVAYYVS--DAAIGAE 7419
Query: 423 HIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ G L + L YM+P + ++ +PL NGK+DR+ L
Sbjct: 7420 ELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKLDRKAL 7457
Score = 217 bits (529), Expect = 1e-54
Identities = 156/458 (34%), Positives = 233/458 (50%), Gaps = 36/458 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEP-SLVIYDDSAD--PSMFKE---SGV 73
I+ LLA KAG AYVP++P++P R+ +++D+ P +L++ + D P + E SGV
Sbjct: 1641 IVGLLAILKAGGAYVPLDPAYPPERLAFMVRDSAPVALLVGGGALDVLPVVEAELAASGV 1700
Query: 74 PFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
P A + A P +E L + +A V+YTSGSTG PKG + A+ NR
Sbjct: 1701 PVLDIGVDAAQWAEAPARNPARSEV--GLAASHLAYVIYTSGSTGTPKGAMNGHRAVVNR 1758
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
L W + D + + KT +F SV E + PLL G L++ E +DP LV +
Sbjct: 1759 LLWMQDAYAL-DGGDAVLQKTPFSFDVSVWEFFWPLLAGARLVMARPEGHKDPAYLVEVI 1817
Query: 194 R------LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
R L VP++L+ + Y G + +K +CSGE LS LA+ + +
Sbjct: 1818 RRERITTLHFVPSMLQIFVEYAEAGSCT----SVKRVMCSGEALSPVLAARLLERL---E 1870
Query: 248 GYKLANFYGSTEVMGDVTYY--VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDS 305
G +L N YG TE DVT + E SD ++PIGRP+ N IY+LD+ P
Sbjct: 1871 GTELHNLYGPTEAAVDVTAWRCAKEASD-----ASVPIGRPISNTQIYILDQHGDPVPIG 1925
Query: 306 EPGEVWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAG 362
GE+ + G + GY+ A RF ++ + + RLYRTGD G L G + Y G
Sbjct: 1926 VAGEIHIGGVQVGRGYLNRPELTAERFVEDRFSGEAG-ARLYRTGDLGRWLGDGTIAYLG 1984
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R D QVKIRG R++L E+E L++ V V+ G+ ++ + + A A+
Sbjct: 1985 RNDFQVKIRGFRIELGEIEARLSEHAAVRDAAVIAREDAPGDQRLVAYYVS--DAAIGAE 2042
Query: 423 HIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ G L + L YM+P + +E +PL NGK+DR+ L
Sbjct: 2043 ELRGHLAARLPDYMVPSAYVHLERLPLTPNGKLDRKAL 2080
Score = 188 bits (458), Expect = 5e-46
Identities = 150/456 (32%), Positives = 227/456 (49%), Gaps = 42/456 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSA-D--PSMFKE---SGV 73
I+ LLA K+G AYVP++P++P R+ +++D+ P+ ++ A D P + E SGV
Sbjct: 561 IVGLLAILKSGGAYVPLDPAYPPERLAFMVQDSAPAALLVGGGALDVLPVVEAELAASGV 620
Query: 74 PFASF-EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN 132
P + AQ A S + + LAP D +A V+YTSGSTG PKGV + + + N
Sbjct: 621 PVLDIGADAAQWAESPAHNLERTETGLAP---DHLAYVIYTSGSTGQPKGVMVEHRGLAN 677
Query: 133 RLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI 192
+ W F + L+F S E+W L G L++ ET RDP+ L+
Sbjct: 678 LVHWHCEVFALRPGTHSSL-VAGLSFDASSWEVWPALCCGGVLVVPRPETARDPEALMAW 736
Query: 193 ER-----LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
+ + +PT + + L+ G +R LR L + G+ L K
Sbjct: 737 WQTQPLDVSFLPTPMAEFV--LSQGLVNRHLRVL---LTGGDRLRK---------LPKAL 782
Query: 248 GYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP 307
+ L N YG TE T +L G+D+ L+ IGRP+ N IY+LDE P
Sbjct: 783 PFALVNNYGPTETTVVATSGLL-GADEAVLH----IGRPISNTQIYILDEHGEPAPIGVA 837
Query: 308 GEVWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRT 364
GE+++ GA +A GY+ A RF ++ + + RLYRTGD G L G + Y GR
Sbjct: 838 GEIYIGGAGVARGYLNRPELTAERFVEDQFSGEAG-ARLYRTGDLGRWLSDGTIAYLGRN 896
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHI 424
D QVKIRG R++L E+E L++ GV V+ G+ ++ + + A A+ +
Sbjct: 897 DFQVKIRGFRIELGEIEARLSEHAGVRDVAVIAREDAPGDQRLVAYYVS--DAAIGAEEL 954
Query: 425 EGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
G L + L YM+P + +E +PL NGK+DR+ L
Sbjct: 955 RGHLAARLPDYMVPSAYVHLERLPLTPNGKLDRKAL 990
Score = 183 bits (445), Expect = 2e-44
Identities = 136/450 (30%), Positives = 218/450 (48%), Gaps = 31/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM------FKESGV 73
I+ LLA KAG AYVP++P++P R+ +++D+ P+ ++ A ++ + +
Sbjct: 2731 IVGLLAILKAGGAYVPLDPAYPPERLAFMVRDSAPAALLVGGGAQAALSVVKAELAAARM 2790
Query: 74 PFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
P A + A P +E LT D +A V++TSGSTG PKGV + + + N
Sbjct: 2791 PVVDIGADAAQWAEAPARNPARSE--VGLTPDHLAYVIHTSGSTGQPKGVAVEHGNVVNF 2848
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
+ W F ++ + T+L F S+CE + PL G A+ ++ + K N+
Sbjct: 2849 IAWAAPAF-VGEALARTLSSTSLNFDISICEWFVPLTVGGAVDVV--RNVLELTKQSNVT 2905
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP+ L ++L + R + GE L + LA + F E L N
Sbjct: 2906 FLNTVPSALDALLKNESFPETVRTVN------VGGEPLKRSLAEQLFATTQVE---LLRN 2956
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T ++ + + IGRP+ N IY+LDE P GE+++
Sbjct: 2957 LYGPTETTVYSTSVLMRRGEPFAAH----IGRPISNTQIYILDEHGEPAPIGVAGEIYIG 3012
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA +A GY+ A RF ++ + + LYRTGD G L G + Y GR D QVKI
Sbjct: 3013 GAGVARGYLNRPALTAERFVEDRFSGEAG-ALLYRTGDLGRWLGDGTIAYLGRNDFQVKI 3071
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L++ V V+ G+ ++ + + A A+ + G L +
Sbjct: 3072 RGFRIELGEIEARLSEHADVRDAAVIAREDVAGDKRLVAYYVS--DAAIGAEELRGHLAA 3129
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++ +PL +NGK+DR+ L
Sbjct: 3130 RLPDYMVPSAYVHLQRLPLTLNGKLDRKAL 3159
Score = 183 bits (445), Expect = 2e-44
Identities = 136/450 (30%), Positives = 218/450 (48%), Gaps = 31/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM------FKESGV 73
I+ LLA KAG AYVP++P++P R+ +++D+ P+ ++ A ++ + +
Sbjct: 5963 IVGLLAILKAGGAYVPLDPAYPPERLAFMVRDSAPAALLVGGGAQAALSVVKAELAAARM 6022
Query: 74 PFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
P A + A P +E LT D +A V++TSGSTG PKGV + + + N
Sbjct: 6023 PVVDIGADAAQWAEAPARNPARSE--VGLTPDHLAYVIHTSGSTGQPKGVAVEHGNVVNF 6080
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
+ W F ++ + T+L F S+CE + PL G A+ ++ + K N+
Sbjct: 6081 IAWAAPAF-VGEALARTLSSTSLNFDISICEWFVPLTVGGAVDVV--RNVLELTKQSNVT 6137
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP+ L ++L + R + GE L + LA + F E L N
Sbjct: 6138 FLNTVPSALDALLKNESFPETVRTVN------VGGEPLKRSLAEQLFATTQVE---LLRN 6188
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T ++ + + IGRP+ N IY+LDE P GE+++
Sbjct: 6189 LYGPTETTVYSTSVLMRRGEPFAAH----IGRPISNTQIYILDEHGEPAPIGVAGEIYIG 6244
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA +A GY+ A RF ++ + + LYRTGD G L G + Y GR D QVKI
Sbjct: 6245 GAGVARGYLNRPALTAERFVEDRFSGEAG-ALLYRTGDLGRWLGDGTIAYLGRNDFQVKI 6303
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L++ V V+ G+ ++ + + A A+ + G L +
Sbjct: 6304 RGFRIELGEIEARLSEHADVRDAAVIAREDVAGDKRLVAYYVS--DAAIGAEELRGHLAA 6361
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++ +PL +NGK+DR+ L
Sbjct: 6362 RLPDYMVPSAYVHLQRLPLTLNGKLDRKAL 6391
Score = 177 bits (431), Expect = 9e-43
Identities = 135/447 (30%), Positives = 217/447 (48%), Gaps = 28/447 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSAD-PSMFKESGVPFASF 78
+ A LA K GAAYVP++ P R+ ++KD E SLV+ A P + +
Sbjct: 4887 VAAELAILKCGAAYVPLDRDVPAERLAFMIKDCEASLVLMARGAVLPEGLEAHRIDIEDV 4946
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A +A++ S S A ++YTSGSTG PKGV + + AI RL
Sbjct: 4947 LRGAGDASNPGLSR----------DSGSDAYIMYTSGSTGTPKGVVIPHRAI-GRLVINN 4995
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-ERLVL 197
++ S+ + + F + E+WGPLL+G ++++ + + +P++LV++ ER +
Sbjct: 4996 GYADFNASDRV-AFAANPAFDATTMEVWGPLLNGGCVVVIDQASVLEPERLVSVMERDGV 5054
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L + L RRL+ + G+ L ++ + L N YG
Sbjct: 5055 TVLWLTAGLFQQYAELLGGVFRRLRYLLVGGDVLDPRSIRHVLRHSRPQ---HLLNGYGP 5111
Query: 258 TEVMG-DVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE +T+ + E ++ +IP+GRP+ N IY+LD P GE+++ GA
Sbjct: 5112 TETTTFAITHEITEVDERAS---SIPLGRPISNTRIYILDAYGDPVPIGVAGEIYIGGAG 5168
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ A RF ++ + + RLYRTGD G L G + Y GR D QVKIRG
Sbjct: 5169 VARGYLNRPELTAERFVEDRFSGEAG-ARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGF 5227
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L++ V V+ G+ ++ + + A A+ + G L + L
Sbjct: 5228 RIELGEIEARLSEHADVRDVAVIAREDVAGDKRLVAYYVS--DAAIGAEELRGHLAARLP 5285
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + +E +PL NGK+DR+ L
Sbjct: 5286 DYMVPSAYVHLERLPLTPNGKLDRKAL 5312
Score = 177 bits (430), Expect = 1e-42
Identities = 134/447 (29%), Positives = 217/447 (48%), Gaps = 28/447 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSAD-PSMFKESGVPFASF 78
+ A LA K GAAYVP++ P R+ ++KD E SLV+ A P + +
Sbjct: 3811 VAAELAILKCGAAYVPLDRDVPAERLAFMIKDCEASLVLMARGAVLPEGLEAHRIDIEDV 3870
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A +A++ S S A ++YTSGSTG PKGV + + AI RL
Sbjct: 3871 LRGAGDASNPGLSR----------DSGSDAYIMYTSGSTGTPKGVVIPHRAI-GRLVINN 3919
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-ERLVL 197
++ S+ + + F + E+WGPLL+G ++++ + + +P++LV++ ER +
Sbjct: 3920 GYADFNASDRV-AFAANPAFDATTMEVWGPLLNGGCVVVIDQASVLEPERLVSVMERDGV 3978
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L + L RRL+ + G+ L ++ + L N YG
Sbjct: 3979 TVLWLTAGLFQQYAELLGGVFRRLRYLLVGGDVLDPRSIRHVLRHSRPQ---HLLNGYGP 4035
Query: 258 TEVMG-DVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE +T+ + E ++ +IP+GRP+ N IY+LD P GE+++ GA
Sbjct: 4036 TETTTFAITHEITEVDERAS---SIPLGRPISNTRIYILDAYGDPVPIGVAGEIYIGGAG 4092
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ A RF ++ + + RLYRTGD G L G + Y GR D QVKIRG
Sbjct: 4093 VARGYLNRPELTAERFVEDRFSGEAG-ARLYRTGDLGRWLEDGTIAYLGRNDFQVKIRGF 4151
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L++ V V+ G+ ++ + + A A+ + G L + L
Sbjct: 4152 RIELGEIEARLSEHADVRDAAVIAREDVAGDKRLVAYYVS--DAAIGAEELRGHLAARLP 4209
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + ++ +PL NGK+DR+ L
Sbjct: 4210 DYMVPSAYVHLQRLPLTPNGKLDRKAL 4236
Score = 171 bits (416), Expect = 6e-41
Identities = 136/450 (30%), Positives = 218/450 (48%), Gaps = 30/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEP-SLVIYDDSAD--PSMFKESGVPFA 76
I+ LLA KAG AYVP++P++P R+ +++D+ P +L++ + D P + E
Sbjct: 8108 IVGLLAILKAGGAYVPLDPAYPPERLAFMVRDSAPVALLVGGGALDVLPVVQAELAAARM 8167
Query: 77 SFEELAQEATSHSADEPMDAE-TLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
++ +A + + E + L + +A V+YTSGSTG PKGV + + ++ N +
Sbjct: 8168 PVVDIGADAAQWAEAPACNPERSEVGLKASHLAYVIYTSGSTGQPKGVMVEHRSLANLVH 8227
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-ER 194
W F +E F + E W PL G L + E RDP+ L+ +
Sbjct: 8228 WHCAAFNLQ-AETRSSLVAGSGFDAATWETWPPLCCGGTLAVPRPEIARDPEALLAWWQT 8286
Query: 195 LVLVPTLLRSILMYLALGP-ASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L + L + + A A+ P L++ + G+ L K + + L N
Sbjct: 8287 QPLDVSFLPTPIAEFAFSQGATNP--HLRVLLTGGDRLRK---------CPKDLPFALVN 8335
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T +L G+D+ L+ IGRP+ N IY+LD P GE+++
Sbjct: 8336 NYGPTETTVVATSGLL-GADEAVLH----IGRPISNTQIYILDAYGEPAPIGVAGEIYIG 8390
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA +A GY+ A RF ++ + + RLYRTGD G L G + Y GR D QVKI
Sbjct: 8391 GAGVARGYLNRPELTAERFVEDRFSGEAG-ARLYRTGDLGRWLGDGTIAYLGRNDFQVKI 8449
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L++ V V+ G+ ++ + + A A+ + G L +
Sbjct: 8450 RGFRIELGEIEARLSEHAAVRDVAVIAREDGPGDKRLVAYYVS--DAAIGAEELRGHLAA 8507
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++ +PL NGK+DR+ L
Sbjct: 8508 RLPDYMVPSAYVHLQRLPLTPNGKLDRKAL 8537
>UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosomal peptide
synthetase - Streptomyces avermitilis
Length = 1768
Score = 221 bits (541), Expect = 4e-56
Identities = 179/614 (29%), Positives = 286/614 (46%), Gaps = 52/614 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A KAGAAY+P++P +P RI ++L D+ LV+ + E +
Sbjct: 334 LVAVYAVLKAGAAYLPVDPGYPVERIRYVLDDSAARLVL-STPRHRDLVHEGREVLDLTD 392
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E A S + + DA LA V+YTSGSTG PKGV++ + ++ NR+ W R
Sbjct: 393 ESAYAKDSTAPEVIGDARDLA--------YVIYTSGSTGNPKGVQIEHRSVVNRINWMQR 444
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
+P + S ++ + KT +F SV E++ + G A+ + RDP+ LV IER
Sbjct: 445 AYPVT-SADVIMQKTPTSFDVSVWELFWWMFEGAAVCLPDPGAERDPEALVTAIERYGVT 503
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG--YKL 251
+ VP++L + L ++ L L+ SGE L+ F + G +L
Sbjct: 504 TMHFVPSMLGAFLDFVVGAGVQAGLVSLRQVFASGEALTPHHVRRFAEVAAATTGPAARL 563
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE DVT++ G D +D +PIGRP+DN I +LD L P PGE+
Sbjct: 564 INLYGPTEATVDVTHHAC-GPDDVD---RVPIGRPIDNTRILVLDSGLRPQPVGVPGELC 619
Query: 312 VAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
+AG LA GY+G A RF P A + +R+YRTGD L G++ Y GR D QV
Sbjct: 620 IAGVGLARGYLGRPELTAERFVAAPAAGE---ERVYRTGDLARWLPDGSIDYLGRIDHQV 676
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG+R++L E+E +L + P V VVL + G + G+V + + + ++ L
Sbjct: 677 KVRGYRIELGEIEESLRRHPQVKDAVVLARKAEDGQTHLCGYVQSADA--LTEEDLKRHL 734
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
L YM+P +++ +++ PL NGK+DR+ L + + +
Sbjct: 735 GVTLPDYMVPARLVALDTFPLSPNGKLDRRAL-----------PEPGPAESESAAYVAPG 783
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
G VLG G + F+ LGGNS++ + + K R G F
Sbjct: 784 TPQEAELARIWGEVLGHERVG---VNDNFFALGGNSIHFVTVLAKARAGGLDFTFQQFFQ 840
Query: 548 ASTLGEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMVESSFYEKAELEQFLKHE 607
T+ ++ ++ G + A + + + + +I Y +L+ L +
Sbjct: 841 NPTVAQLARSLA---RSGPGEQPAALSPFELLEPEDRALIPAGVEDAYPMTQLQAGLVFQ 897
Query: 608 IE----TRDYADCI 617
E T +Y D +
Sbjct: 898 SELSHGTAEYHDIL 911
>UniRef50_Q5J1Q6 Cluster: NocB; n=1; Nocardia uniformis subsp.
tsuyamanensis|Rep: NocB - Nocardia uniformis subsp.
tsuyamanensis
Length = 1925
Score = 221 bits (541), Expect = 4e-56
Identities = 156/454 (34%), Positives = 237/454 (52%), Gaps = 31/454 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I A+L +AGAAY+P++P P R+ +L DA +++I D + P +
Sbjct: 98 IAAVLGALRAGAAYLPLDPELPAPRLEFLLADAGAAVLITDTATREGPVAAHDGPTVLCD 157
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L+ + + EP AE S A V+YTSGSTG PKGV + + ++ NRL W
Sbjct: 158 RLSPDGAPTA--EPT-AEPAEFPGSALAAYVIYTSGSTGRPKGVAVDHRSLVNRLLWMRE 214
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER----- 194
+ + + + KT+ F SV E PL+ G L+I +ET RD LV + R
Sbjct: 215 RYGVGQGD-VVLHKTSFGFDVSVWEQLLPLISGARLVIAPQETRRDATALVRLVRAESVT 273
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP+LL + L + A R L++ + SGE L K +A +F + + L N
Sbjct: 274 VLHFVPSLLPAFLDVAEVEQA----RALRVAISSGEALPKPVAVDFARRLPH---CALHN 326
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ ++G D+ P +PIG P+DN ++Y+LD+ L P GE+ +
Sbjct: 327 LYGPTEATIDVTHWPVDGDDER---PFVPIGTPIDNTSVYVLDDHLEPLPVGAEGELCIG 383
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G +A GY+G A +F +P R+YRTGD GA+ Y GR D QVK+
Sbjct: 384 GQAVALGYLGRPALTAEKFAPDPFGAPG--ARMYRTGDRARFGPDGAIEYLGRRDGQVKL 441
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP----GARTSAQHIEG 426
RG+RV+L E E AL + V + V+ G + G ++GFV+ +P GA + H+
Sbjct: 442 RGYRVELGETEAALLESDLVRQAAVVVRG-EGGAKRLVGFVSGRPDAAGGAEGAEAHVLA 500
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+L + L Y +P Q++ ++++PL +GKVDR L
Sbjct: 501 RLSATLPAYQVPSQLVWLDALPLTPSGKVDRAAL 534
Score = 161 bits (391), Expect = 7e-38
Identities = 135/448 (30%), Positives = 205/448 (45%), Gaps = 32/448 (7%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ALLA ++GA V ++P P R+ DA + V+ +AD + F+ V
Sbjct: 1178 IALLAVHRSGAVPVLLDPEHPVARLREAAADAGVAAVV--TTADQAGFEAWPVVHPDGGI 1235
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
+A T +A P A+ A V+YTSGSTG PKGV + + NR+ W R
Sbjct: 1236 VAP--TEPAACRPGSADPARD------ACVVYTSGSTGGPKGVLAPQAGLVNRVLWSGRA 1287
Query: 141 FPYSDSEEICVWKTALTFVD-SVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLVL 197
FP + + TA T D ++ E++ PL HG A++ ++ DP L + V
Sbjct: 1288 FPTPEPPRVLA--TAGTAFDIALWELFFPLAHGGAVVTAPQDAVLDPDALAELIVAERVT 1345
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V L S+L P + L + GE ++ + F G+ +L YG
Sbjct: 1346 VAHFLPSLLAAFLDSPKAAGCTGLAHVLSGGEAVTPAIVRAF---TGSGLPARLHQAYGP 1402
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
E VT++ D L +PIGRP+D +++DE L GE+ V G +
Sbjct: 1403 AEASISVTHHTCAPED--GLRERVPIGRPIDGAGAHVVDEHLRELPVGCVGELAVTGVAV 1460
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
AGY A RF NP QP LY TGD G + + GR D QVK+RGHR
Sbjct: 1461 GAGYPNDPELTARRFPANPFGAQP----LYLTGDLARWGADGELEFLGRRDRQVKVRGHR 1516
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+ EV+R PGV + V + + + F + GA + LR L
Sbjct: 1517 VEPAEVDRTAELHPGVRQAVTVF-----RDGALTTFAAPRAGALLDVADLRRLLRERLPD 1571
Query: 435 YMMPQVIEVESIPLLVNGKVDRQGLLKM 462
+M+ +++ ++++P+ NGKVD++ LL +
Sbjct: 1572 WMVGELVVLDALPVTGNGKVDQRALLDL 1599
>UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 5741
Score = 221 bits (541), Expect = 4e-56
Identities = 154/450 (34%), Positives = 226/450 (50%), Gaps = 30/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P +P+ R+ ++L DA +++ + ++S
Sbjct: 2649 VVGLLGVLKAGGAYVPLDPEYPRERLEYMLADAAAPVLLTQARLSERLPRDSATVVCLDS 2708
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E +A + +E +D + +A VLYTSGSTG PKG +++AICNRL W
Sbjct: 2709 EW--DAVAREREERLDVT----VDGSGLAYVLYTSGSTGRPKGAMNTHAAICNRLLWMQE 2762
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
+ S+ + + KT +F SV E + PLL G L++ R+P L + I
Sbjct: 2763 AYGLDSSDRV-LQKTPFSFDVSVWEFFWPLLAGARLVMARPGGHREPAYLTDTIARERIT 2821
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++LR L L + LRR+ CSGE L EL +F E L N
Sbjct: 2822 TLHFVPSMLRPFLEETELAVSCASLRRV---FCSGEALPPELRDRYFSCLLAE----LHN 2874
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT + D+ + +PIGRP+ N +Y+LD L P PGE+++
Sbjct: 2875 LYGPTEAAVDVTAWACAREDRGHV---VPIGRPIANARMYVLDARLRPVPAGVPGELYIG 2931
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA LA GY A RF + A QP R+YRTGD L GA+ Y GR D QVK+
Sbjct: 2932 GAPLARGYWQRPDLTAERFLPDAFAAQPG-ARMYRTGDQARFLANGAIEYLGRLDDQVKL 2990
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L+ PGV V G+ ++ +V G A + L
Sbjct: 2991 RGFRIELGEIEAVLSLHPGVRAAAVAIREDVPGDRRLVAYVVAPSG--DVASELRAFLGE 3048
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L +M+P + ++++PL +GK+DR+GL
Sbjct: 3049 RLPEHMVPSAFVTLDALPLSPSGKLDRRGL 3078
Score = 182 bits (444), Expect = 2e-44
Identities = 146/451 (32%), Positives = 219/451 (48%), Gaps = 28/451 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAGAAYVP++P++P+ R+ ++ DA +++ + VP
Sbjct: 4128 VVGMLGILKAGAAYVPLDPAYPRERLAWMIADAGAPVLLTQERL------RGAVPSEGVS 4181
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L E S D A A + + A V+YTSGSTG PKGV +S+ A+ RL +
Sbjct: 4182 VLTVEEVSAQGDVAETAALGAGVGAADAAYVIYTSGSTGTPKGVCVSHQAVV-RLVVETD 4240
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + A +F + EIWG LL+G ++ + RET P + R +
Sbjct: 4241 FIRVVPEDRVAQASNA-SFDAATFEIWGALLNGARVVGVERETALSPSAFASWLREEGIR 4299
Query: 200 TLLRSILMYLALGP----ASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
L + + + A LR+L GE + + E +L + Y
Sbjct: 4300 VLFLTTAWFNQVAAEVPDAFSGLRQLHF---GGEAVDPRPVRRVLREGAPE---RLLHVY 4353
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T++++ +D + +IPIGRPL N Y+LDE+++P GE+W+ G
Sbjct: 4354 GPTENTTFSTWHLV--TDVPEGAVSIPIGRPLANTVQYVLDEDMAPVPPGGVGELWLGGD 4411
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRG 372
LA GY+G A RF NP + +P RL+RTGD L GAV + GR DAQVK+RG
Sbjct: 4412 GLAWGYLGQPALTAERFVPNPFSERPG-TRLFRTGDRVRLLADGAVTFEGRVDAQVKVRG 4470
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDR-GNPEILGFV--TTKPGARTSAQHIEGKLR 429
RV+ EVE AL + P V + VVL + G+ ++ +V T + A + L
Sbjct: 4471 FRVEPGEVEAALLRHPDVRQAVVLAREDEAGGSRRLVAYVVPTAEAAATPEPSLLRTFLA 4530
Query: 430 SALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
+ L YM+P V +PL NGKVDR+ L
Sbjct: 4531 AHLPAYMVPAAFMVLGRLPLTPNGKVDRRAL 4561
Score = 172 bits (419), Expect = 3e-41
Identities = 143/451 (31%), Positives = 227/451 (50%), Gaps = 35/451 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSAD---PSMFKESGVPFA 76
++ +L KAG AYVP++P++P+ R+ +++D +V+ S PS + + +
Sbjct: 5189 VVGMLGILKAGGAYVPLDPTYPRERLAFMVEDTRLPVVLAQQSVVALLPSGSADVVLLDS 5248
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+++E+A+E T + P ++S+A V+YTSGSTG PKGV + A+ RL
Sbjct: 5249 AWDEIAREPT-------VSPRVTVP--AESLAYVMYTSGSTGRPKGVCVPQRAVA-RLVL 5298
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLIL-SRETTRDPQKLVNIERL 195
R F ++E+ + + F + E+WG LLHG L++ ++ T D K V
Sbjct: 5299 GSR-FARWGADEVFLQLAPICFDAATFEVWGALLHGAKLVLFPAQPPTVDTLKDVLARHG 5357
Query: 196 VLVPTLLRSILMYLALGPASRP--LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V TL + ++ AL A+RP L ++ + G+ L E G G L N
Sbjct: 5358 VT--TLWLTAALFEALS-AARPDALDGVRQLLAGGDVLPPAAVRE---RLGR--GGILVN 5409
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE +V+EG+ + P IPIGRP+ N +Y++D L P PGE+ +
Sbjct: 5410 GYGPTEGTTFTCCHVMEGA----VAPGAIPIGRPIANTRVYVVDAALRPVPVGVPGELLI 5465
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVK 369
G LA GY G A RF NP ++ RLYRTGD + G + + R D QVK
Sbjct: 5466 GGDGLAWGYQGRPELTAERFVPNPFGSEAG-GRLYRTGDSVRYREDGTLEFLERLDGQVK 5524
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG+RV+ EVE AL P V + VV+ G ++ + + G + + G L
Sbjct: 5525 VRGYRVEPGEVEEALRLHPSVAEAVVVARPDPAGGKRLVAYAVPRAGETLDPRGLRGFLA 5584
Query: 430 SALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
+L +M+P ++ + ++PL GK+DR+ L
Sbjct: 5585 ESLPEFMVPSTLVPLMALPLTPVGKLDRRAL 5615
Score = 127 bits (307), Expect = 1e-27
Identities = 89/272 (32%), Positives = 135/272 (49%), Gaps = 17/272 (6%)
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ L P+L +++L+ A L RL + GE LS ELA G L
Sbjct: 1761 VTHLQCTPSLAQALLLEPGAAGALVGLERL---LVGGEALSAELAERLRGTMGGA----L 1813
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE + + ++GS +PIG P+ N ++Y+LD EL P PGE++
Sbjct: 1814 LNMYGPTETTIWSSSHAVDGSPG-----PVPIGTPIANTSLYVLDAELRPLPVGVPGELY 1868
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+ G +A GY A RF +P A+ R+YRTGD G V + GR D Q+
Sbjct: 1869 IGGMGVARGYHARPELTAERFLPDP-ASSNAGARMYRTGDRARWRADGTVEFLGRVDHQL 1927
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG RV+ E+E LA+ V + VV+ G ++ +V +PG S + +
Sbjct: 1928 KVRGFRVEPGEIESVLARHSDVAQAVVVAREASAGGARLVAYVVARPGTALSVEALLAFS 1987
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
R +L +M+P + ++++PL NGKVDR+ L
Sbjct: 1988 RRSLPEHMVPSAFVPLDALPLTPNGKVDRKAL 2019
Score = 63.7 bits (148), Expect = 2e-08
Identities = 124/482 (25%), Positives = 194/482 (40%), Gaps = 62/482 (12%)
Query: 29 AGAAYVPMEPSFPQG------RITHILKDAEPSLVIYDDSADPSMFKESGVP-FASFEEL 81
AG VP P P R+ I++DA S+V+ S +E G F EL
Sbjct: 107 AGLVAVPAYPPDPMRLERTLPRLRAIIRDARASVVL-----TTSFIQEMGEGLFEGAPEL 161
Query: 82 A--QEATSHSADEPMDAETLAPLTS-DSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A + + + E +A P S D++A + YTSGSTG PKGV+LS+ + + L
Sbjct: 162 AALRWVATDALPEGTEAGWRRPEPSRDTLAFLQYTSGSTGDPKGVQLSHGNLLHNLGLIS 221
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRET-TRDPQK-LVNIERL- 195
F +W + + I PL G + ++S R P+ L ++ R
Sbjct: 222 HAFQVRSDSVGVIWLPPYHDMGLIGGILQPLYAGFPVALMSPLAFLRRPRFWLESLSRFG 281
Query: 196 --VLVPTLLRSILMYLALGPASRP---LRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
+ L + PA R LRR +L C E + E+ + F + F +
Sbjct: 282 GTISGGPCFAFDLCVRKVPPAEREGLDLRRWELAFCGAEPIRPEVMTRFSEAFAPVGFQR 341
Query: 251 LANF--YGSTEVM--------GDVTYYVLEGSDQLDLYPTI-----PIGRPLDNCAIYLL 295
A + YG E G+ + + L+ + P RPL C L
Sbjct: 342 EALYPCYGLAEGTLIASGGRKGEGVLTRMWDAQALERNEALAAEDGPGARPLVGCGQTLP 401
Query: 296 DEEL----SPTRDSEP----GEVWVAGANLAAGYVGGGGANRFCDNPH-ATQPEFQRLYR 346
++ L TR + P GE+WV+G ++A GY + A R R
Sbjct: 402 EQTLLVVDPETRRACPPERVGEIWVSGPSVAHGYWERPEESEAAFGARLADSDSGPRFLR 461
Query: 347 TGDFGTLVKGAVLYAGRTDAQVKIRG---HRVDL-LEVERALAQV-PGVDKCVVLCYGLD 401
TGD G L G + GR + +RG H DL L +ER+ + + PG + +D
Sbjct: 462 TGDLGLLKDGELFVVGRRKDLIILRGRNLHPQDLELTLERSHSALRPGCG----AAFSID 517
Query: 402 RGNPEILGFVTTKPGART-SAQHIEGKLRSAL--THYMMPQ---VIEVESIPLLVNGKVD 455
G E L + + +A+ + G +R L TH + +IE ++P +GK+
Sbjct: 518 VGGEERLAVMYEVDSRKPWTAEDVVGAVRRGLAETHEVQLHTLVLIEPGALPKTSSGKIQ 577
Query: 456 RQ 457
R+
Sbjct: 578 RR 579
Score = 60.1 bits (139), Expect = 2e-07
Identities = 35/108 (32%), Positives = 58/108 (53%), Gaps = 11/108 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL +KAG AY+P++PS+P+ R+ +L+D+ S+V+ +PF
Sbjct: 1228 VVGLLGIFKAGGAYLPLDPSYPEARLALMLEDSGASVVL------AHRHLAGALPFGDRT 1281
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSY 127
+ + + DA + D++A VLYTSGSTG PKGV + +
Sbjct: 1282 VVPLDVAGEA-----DAAPPGAVGPDNLAYVLYTSGSTGKPKGVLIPH 1324
>UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
fluorescens (strain PfO-1)
Length = 5422
Score = 220 bits (537), Expect = 1e-55
Identities = 175/540 (32%), Positives = 263/540 (48%), Gaps = 42/540 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG YVP++P++P R+ ++LKD+ PS V+ S ++ E VP +
Sbjct: 4903 VVGLLAILKAGGGYVPLDPAYPLERLAYMLKDSAPSAVLVQGST-RALLGEVAVPVVDLD 4961
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ S SAD P ++ LT A V+YTSGSTG PKGV +S + NRL W
Sbjct: 4962 HDTWQ--SLSADNP----SVDGLTPQHTAYVIYTSGSTGQPKGVINEHSGVVNRLLWMQD 5015
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + +E+ + KT +F SV E + PL+ G L++ +DP L + +
Sbjct: 5016 AYRLT-AEDSVLQKTPFSFDVSVWEFFWPLMTGARLVMARPGGHKDPLYLSEVIEQQQIT 5074
Query: 200 TL--LRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
TL + S+L ++LA G +R L+ +CSGE L L F + G L N YG
Sbjct: 5075 TLHFVPSMLDVFLAHGDTAR-CSALRQVMCSGEALPGSLVRRFKQQL---PGSGLHNLYG 5130
Query: 257 STEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE DVT + G ++ P PIG+P+ N +Y+LD + P GE+++ G
Sbjct: 5131 PTEAAVDVTAWDCAG--PIETTPDNTPIGKPIANTRLYILDAQQQPVPQGVVGELYIGGV 5188
Query: 316 NLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
+A GY+ A RF ++P +P R+YRTGD L G + Y GR D QVKIRG
Sbjct: 5189 QVARGYLNRPELSAERFLNDPF--KPN-GRMYRTGDVARYLADGNIEYLGRNDDQVKIRG 5245
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E++ L + GV + VVL G+ ++ + T GAR + G L L
Sbjct: 5246 LRIELGEIQSRLTDISGVQEAVVLAREDVPGDKRLVAYYT---GARLVIDVLRGHLLEHL 5302
Query: 433 THYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P V + + ++PL NGK+DR+ L ++ + E V
Sbjct: 5303 PDYMVPAVFVHLGALPLSPNGKLDRKALPAPDQSAAITREYEAPV------------GEV 5350
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
+ A L R + F+ELGG+SL ++ I +LR G E+ TL
Sbjct: 5351 EILLAGLWAELLNVER--VGRHDNFFELGGHSLLAVSLIGRLRQEGMEAEVRALFEQPTL 5408
Score = 210 bits (512), Expect = 1e-52
Identities = 156/540 (28%), Positives = 260/540 (48%), Gaps = 40/540 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P++P R+ ++LKD+ P + + A ++F+ GVP F+
Sbjct: 611 VIGLLGILKAGGAYVPLDPAYPAERLNYMLKDSAP-VALLAHGATRALFEAGGVPLLDFD 669
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ H D P + L + ++A V+YTSGSTG PKGV + + + N L W +
Sbjct: 670 Q------DHWQDYPEHNPQVPGLNASNLAYVIYTSGSTGTPKGVMVEHRGLGNLLHWSSQ 723
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLV 196
P ++ + KT +F SV E++ PL G L++ + +P L + +R+
Sbjct: 724 VCP-PVADGALLQKTPYSFDASVWELFWPLTAGLRLVLARPDAHFEPAYLTQVVQEQRIS 782
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
++ + + +L + S+ ++ C G L+ EL + + +L N YG
Sbjct: 783 VIQFVPALLQQFLDVENVSQCTSLTDVF-CGGGELTPELGRQVRERLPQ---VRLHNVYG 838
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE D + + LE S + +PIGRP+ N +Y+LDE+L P GE+++ G
Sbjct: 839 PTETTVDSSVWTLEPSMPVP-EALLPIGRPVSNTRLYILDEQLQPLPLGVAGELYIGGVQ 897
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
+A GY+ A RF D+P + QP RLYRTGD G + Y GR D QVK+RG
Sbjct: 898 VARGYLNLASLTAERFLDDPFSDQPN-ARLYRTGDLCRYRADGNLEYLGRNDDQVKVRGL 956
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E++ L Q+ V VL G+P ++ + T G + L L
Sbjct: 957 RIELGEIQTRLTQLATVLAAEVLVREDVAGDPRLVAYYT---GGPLEIGELRSHLLEQLP 1013
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAV-DIDCSXXXXXXXXXX 491
YM+P + + ++PL NGK+DR+ L +++ E V D++C
Sbjct: 1014 DYMVPTAFVHLAAMPLSPNGKLDRKALPAPDQSSQILRGYEAPVGDVEC----------- 1062
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
+ L R + F+ELGG+SL ++ + ++R + ++ G T+
Sbjct: 1063 --RIAEIWQALLNVER--VGRHDNFFELGGHSLLAVKLVERMRQQELSCDVRVLFGRPTV 1118
Score = 176 bits (428), Expect = 2e-42
Identities = 139/450 (30%), Positives = 215/450 (47%), Gaps = 33/450 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P++P R+ ++LKD+ P V+ A + ES +
Sbjct: 3825 MVGLLGILKAGGAYVPLDPAYPAERLDYMLKDSAPVAVLVH-GATRELLDESTALVIDLD 3883
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +H P D + L++ ++A V+YTSGSTG PKGV + + + N L W +
Sbjct: 3884 Q------AHWTFNPDDNPQVLGLSASNLAYVIYTSGSTGAPKGVMVEHRGVGNLLHWSSQ 3937
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER----- 194
P + ++ + KT +F SV E++ PL G L++ + R+P L + R
Sbjct: 3938 LCP-AVTDGALLQKTPFSFDASVWELFWPLSAGLRLVLARPDGHREPAYLAQVIREQRVS 3996
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP LL+ L + S L C G L+ LA + +L N
Sbjct: 3997 VIQFVPVLLQQFLEQDDVSQCS----SLTDVFCGGGDLTPALARLVRERLPQ---VRLHN 4049
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D T + LE S + +PIGRP++N +Y+LD P G++++
Sbjct: 4050 VYGPTEATVDSTVWTLEPSMAVP-DSALPIGRPINNTRLYVLDAAKRPVPMGVIGQLFIG 4108
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
GA +A GY+G A RF +P RLY TGD G + + GR D QVK+
Sbjct: 4109 GAGVARGYLGLPQLMAERFTPSPFVAG---DRLYATGDLVRYRADGQLEFIGRNDFQVKL 4165
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++ E+E L P + + VVL R + F + + + L +
Sbjct: 4166 RGLRLEPGEIEAQLLSHPALREAVVLV----REERLVAYFTWHAEAGQPGIEALREHLLA 4221
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++S+PL NGKVDR+ L
Sbjct: 4222 RLPDYMVPSAFVALDSLPLSPNGKVDRKAL 4251
Score = 169 bits (411), Expect = 2e-40
Identities = 133/450 (29%), Positives = 226/450 (50%), Gaps = 36/450 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A LA K AAYVP++ + P R +++D+ +++ + + V +
Sbjct: 1688 LAAQLAIGKCAAAYVPLDINAPGERQAFMVEDSSAKVLLTLSTET----VDYAVRRIDLD 1743
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L +A +P+ L P +S+S+A ++YTSGSTG PKGV + + AI RL
Sbjct: 1744 SLPLDA------QPVHNPGL-PQSSESVAYIMYTSGSTGTPKGVMVPHRAI-GRLVINNG 1795
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ----KLVNIERL 195
++ + + + + F S ++WGPLL+G ++++ T DPQ +L N
Sbjct: 1796 YADFNPQDRV-AFASNPAFDASTMDVWGPLLNGGRVVVIDHATLLDPQAFGRELANTGAT 1854
Query: 196 VL-VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+L V T L + Y+ L P + L+ L++ +C GE + F + ++ +
Sbjct: 1855 ILFVTTALFN--QYVQLIPEA--LKGLRIVLCGGERAD---PAAFRRLLAEAPDLRIIHC 1907
Query: 255 YGSTEVMG-DVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T+ V E S+ + ++PIG P+ N +Y+LD P GE+++
Sbjct: 1908 YGPTETTTYATTFEVREVSETAE---SVPIGGPISNTQVYVLDARQQPVPMGVTGELYIG 1964
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ A +F +P + QP LYRTGD L G + GR D QVKI
Sbjct: 1965 GQGVALGYLSRPDLTAEKFLQDPFSEQPG-ALLYRTGDLARWLAPGQLECIGRNDDQVKI 2023
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L GV + +VL + ++ + T + G +++ + +L++
Sbjct: 2024 RGFRIELGEIENRLLNCDGVKEAIVLARQDGQEPLRLVAYFTAEKGVDSAS--LREQLQA 2081
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P ++++++PL NGKVDR+ L
Sbjct: 2082 RLPEYMVPSAWVQLDALPLNNNGKVDRKAL 2111
Score = 168 bits (408), Expect = 6e-40
Identities = 159/546 (29%), Positives = 246/546 (45%), Gaps = 52/546 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGA YVP++P+ P RI ++L+D++P V+ A S + G+
Sbjct: 2762 LVGLLAILKAGAGYVPVDPAHPAERIAYLLQDSDPVAVL----AQASTRELLGM--MPVI 2815
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L +A H D L LT ++A V+YTSGSTG PKGV + ++ + N + W
Sbjct: 2816 DLDSDAWQHLPD---SNPQLPYLTPANLAYVIYTSGSTGQPKGVMVEHATLENLVHWHAE 2872
Query: 140 TFP-YSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
F ++ S V F E+W L G A L L ET + ++
Sbjct: 2873 AFDLHAGSHTASV--AGFGFDAMAWEVWPALCVG-ATLHLPPETVSNEHLDELLDWWRAQ 2929
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
P + + +A SR L+ L TL + + + F + + N YG T
Sbjct: 2930 PLQVSFLPTPVAEYAFSRELQHPTL-----RTLL--IGGDKLRQFNRAQTFAVINNYGPT 2982
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E V+ S +++ + IGRP+ N IYLLD++ P GE++VAGA +A
Sbjct: 2983 EAT------VVATSGLVEVGQPLHIGRPMANARIYLLDDQQRPVPVGVTGEMYVAGAGVA 3036
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +P + QP+ R+YRTGD L G + Y GR D QVK+RG RV
Sbjct: 3037 RGYLNRPDLTAERFLTDPFSDQPQ-ARMYRTGDLARWLADGNIEYLGRNDDQVKLRGVRV 3095
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E ALA P V V L R ++ F P + + L++ L
Sbjct: 3096 ELGEIEAALASHPAVQDAVALV----RDGQLLVWFTERAP---ADIEALRNHLQTRLPQA 3148
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
++P + ++++PL NGK+DR+ L + +N + E A
Sbjct: 3149 LIPAAYVRLDALPLTANGKLDRKVLPEPDQNAWLS--REYAAPQGPMETALAQIWADVLK 3206
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEV 554
VG F+ELGG+SL ++ I +LR G ++ TL +
Sbjct: 3207 LEKVGR------------HDNFFELGGHSLLAVSLIERLRQIGLNTDVRVLFSQPTLAAL 3254
Query: 555 LSKMST 560
+ + +
Sbjct: 3255 AAAVGS 3260
>UniRef50_Q8DTJ5 Cluster: Putative bacitracin synthetase 1; BacA; n=1;
Streptococcus mutans|Rep: Putative bacitracin synthetase
1; BacA - Streptococcus mutans
Length = 2724
Score = 219 bits (534), Expect = 3e-55
Identities = 163/569 (28%), Positives = 279/569 (49%), Gaps = 45/569 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L K+GAAYVP+EPS P+ R+ +IL D+ +I ++ PF + +
Sbjct: 1288 MVTILGVLKSGAAYVPIEPSLPEERVKYILDDSCCDFIISEE------------PFYNGK 1335
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ ++ +EP ++ + T + ++YTSGSTG PKGV L++ A+ NRL W
Sbjct: 1336 INSETISNILNEEPDISKVESDSTYKDLCYIIYTSGSTGDPKGVMLTHEAVMNRLLWMQN 1395
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+P + +I + KT+ F S+ E++G G L L +DPQ+++ NI
Sbjct: 1396 AYPIT-KNDIILQKTSFGFDVSIWELFGWTFEGAVLYFLENGEEKDPQRIIELINSQNIS 1454
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+L VP++L ++ + L+ L + SGE L+KE +F+ F N D +L N
Sbjct: 1455 KLHFVPSML-NVFLEFCERENKDSLKSLSIVFSSGEALTKEQVIKFYSIFDN-DKPQLIN 1512
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE +VTY+ D +PIG PLDN Y+L+++ GE+++
Sbjct: 1513 LYGPTETAIEVTYFDCSNLDYKS--EDVPIGEPLDNVEAYVLNDKKQKCPIGVVGELYIG 1570
Query: 314 GANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKI 370
G +A GY+ A + F P + RLY TGD +G +++ GR+D QVKI
Sbjct: 1571 GIQVAQGYINKEDATKKSFVRLPKISN---SRLYATGDLVKWTSEGKLIFIGRSDDQVKI 1627
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG+R++L E+E+ L +V + V L L + N ++ ++ + I+ +L++
Sbjct: 1628 RGYRIELGEIEKYLKKVSQKNCLVSLQNKLSKNNKSLIAYI--ESSTTIDESKIKEELKT 1685
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P + V P+ +GKVDR+ L MY + + +A
Sbjct: 1686 LLPQYMVPSHIYIVPEFPINKSGKVDRKLLDSMYSSKH------IA-----PKEGLIKSS 1734
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
+V + + + + S F+ LGG+S+ +I +KL +GY V + + L
Sbjct: 1735 NLTEDIKSVWSNILDYSIDSFSEDDNFFSLGGDSIKAISMASKLISKGYKVSVKEILKNP 1794
Query: 550 TLGEVLSKMSTDPNGGADSKEATFTAVPM 578
T+ + L+K+ N + E +VP+
Sbjct: 1795 TIAQ-LTKIVVKSNQIEEDSELD-NSVPL 1821
Score = 146 bits (353), Expect = 3e-33
Identities = 127/457 (27%), Positives = 214/457 (46%), Gaps = 37/457 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ + A K+G A+ P+ +P RI HI+K+ + VI + A+ + KE +
Sbjct: 261 IVIFAILKSGFAFSPISLDYPPERIEHIIKETHLNSVIVPEEANLQISKEIK------QY 314
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
+A++ + + E + D IA V++TSG+TG PKGV++S+ ++ N + W
Sbjct: 315 VAKDLLNKAPVEVDQFSNAVNVRGDDIAYVIFTSGTTGTPKGVKVSHQSLMNLITWHNDN 374
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLVLV 198
F + SE I + F S+ E++ L G + ++S + D +KL IE V +
Sbjct: 375 FSIT-SETIAAKYAGVAFDASIWELFPYLSIGAKVYVVSEKDRFDVKKLNQKFIENKVSI 433
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L +++ P LK+ + E L YF +E Y+ N YG T
Sbjct: 434 AFL--PTVVFEKFSKVQNPY--LKILLTGAEKL---------HYF-SEQAYEQYNNYGPT 479
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T + LE +D IPIG+P+ N ++ + GE+++ G +L+
Sbjct: 480 EYTVVATSFKLE--KHMD---NIPIGKPIANTTALVMSNDRHFLPIGFKGELYLGGDSLS 534
Query: 319 AGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGHRV 375
+GY+ N F + Q Q Y+TGD G +LY GR D Q+KI G+R+
Sbjct: 535 SGYLNDSKKTKNSFIE---LEQIMGQVFYKTGDLVAYTDSGELLYYGRIDNQIKINGYRI 591
Query: 376 DLLEVERALAQVPGVDK-CVVLCYGLD-RGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
+L ++E+ + ++ G D C V+ + G + F G ++ + +L + L
Sbjct: 592 ELQDIEKNILEIIGQDSDCSVVVIPVSINGLISLHAFYEGVTGFDSNPNQVLKQLTNKLP 651
Query: 434 HYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNN 469
YM+P IE + PL NGKVDR+ L K+ N + +
Sbjct: 652 SYMVPSTIESLSQFPLTSNGKVDRKYLEKIVLNKSTS 688
>UniRef50_Q87WM7 Cluster: Non-ribosomal peptide synthetase, terminal
component; n=1; Pseudomonas syringae pv. tomato|Rep:
Non-ribosomal peptide synthetase, terminal component -
Pseudomonas syringae pv. tomato
Length = 3432
Score = 219 bits (534), Expect = 3e-55
Identities = 174/549 (31%), Positives = 263/549 (47%), Gaps = 39/549 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++LL KAG AYVP++P +P+ RI ++L DA P L + S+ K + +
Sbjct: 2652 VVSLLGVLKAGGAYVPIDPHYPEERIAYMLADAAPILTM----TQRSLLKLTALQRTDSL 2707
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + ATS + + + L + +A +YTSGSTG PKG S+ AI NR+ W
Sbjct: 2708 CLDEHATSLAHLPKTNPQRL--IDPACLAYCIYTSGSTGAPKGSLNSHEAIINRILWMQD 2765
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERL-VL 197
T+ D+ + + KT +F SV E + PL G +L+ E +DP+ L IER V
Sbjct: 2766 TY-LLDATDRVLQKTPFSFDVSVWEFFWPLSVGARMLLAKPEGHKDPRYLETLIEREGVT 2824
Query: 198 VPTLLRSILM-YLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ S+L Y+AL AS R L+ SGE LS + +EFFK + +L N YG
Sbjct: 2825 TAHFVPSMLSAYMALTQASHT-RALRRVFSSGEALSTSVQNEFFKRY---PATQLHNLYG 2880
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DVT++ + D + +PIGRP+ N Y+LDE L P G +++AG
Sbjct: 2881 PTEAAIDVTHWHCQAGD---VGHAVPIGRPVANTRTYILDETLQPVPIGVTGNLYLAGVQ 2937
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
L+ GY+ A RF +PH T R+Y TGD G + Y GR D Q+K+RG
Sbjct: 2938 LSRGYLKRVDLTAERFIPDPHGTPGS--RMYMTGDTARYRAHGEIEYLGRNDQQIKLRGF 2995
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L P V + VV D NP + ++ + S + L L
Sbjct: 2996 RIELGEIEMQLCAHPQVSQAVVSVNTSDADNPTLTAYLVCNADTQPSVDELRECLARTLP 3055
Query: 434 HYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM + ++ +PL NGKVDR+ L + + A+ +
Sbjct: 3056 DYMADVCFQFLDHLPLTSNGKVDRRALPQPVSAVRDQ-----AIQL---------LAPRT 3101
Query: 493 XXXXTVGAVLGRAAR-GTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEISDFLGAST 550
+V AV +SL F+ GG+SL ++ I ++ R+ G + D ++T
Sbjct: 3102 ALEKSVAAVWKNTLNLEFISLNDNFFHEGGHSLLAMKMIDQVNRELGLAARVRDIFESAT 3161
Query: 551 LGEVLSKMS 559
LG + K+S
Sbjct: 3162 LGAFIEKIS 3170
Score = 199 bits (486), Expect = 2e-49
Identities = 169/567 (29%), Positives = 266/567 (46%), Gaps = 36/567 (6%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+A+LA KAGA VPM+PS+P R+ + +DA L+I + P V S
Sbjct: 1593 VAILAVLKAGAVCVPMDPSYPTERLRFMAQDARADLIITLTTLRPR------VEGCSHTI 1646
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
+ + + + EP + P + V+YTSGSTG+PKG L++ + N + WQ
Sbjct: 1647 ICMDQCADAWHEP-SSNPARPQNLLDLCYVIYTSGSTGLPKGAALTHEMLTNLVQWQLTE 1705
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVPT 200
S + + + L+F S E + G L+++S +T RDP L+ + + +
Sbjct: 1706 SRLSRGDNTLQF-SPLSFDVSFDEFFSTWASGGTLVMVSEDTRRDPVLLLELIQRQNIAR 1764
Query: 201 LLRSILMYLALGPASRPLRR---LKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L + + A+R + + LK VC GE L ++ E F L N YG
Sbjct: 1765 LFIPFVALQGIADAARDVDKLACLKEVVCGGEQL--QVTQEVVDLFQKLPDALLHNQYGP 1822
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE VT Y L G D PIG+PL N +Y+LD L P G++++AG +L
Sbjct: 1823 TE-SHFVTGYRLSG-DATQWPALPPIGKPLFNSQMYVLDASLEPVPVGVRGDLYIAGVHL 1880
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A Y A RF NPH+ P R+Y+TGD L G + Y GR+D QVKIRG R
Sbjct: 1881 ARCYWERPDITAERFVPNPHSLSPG-ARMYKTGDVARYLPDGNIEYLGRSDHQVKIRGFR 1939
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L EVE+AL V + G +++G++ K + I+ LR L
Sbjct: 1940 IELAEVEQALMAQETVASAAAMVREDRPGLKKLVGYLVAKSDCTLNIVDIKEHLRRTLPD 1999
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P + + ++PL +GKVD++ L EN +N+++ VA D
Sbjct: 2000 YMVPTTFVILPTLPLTPSGKVDKRS-LPQPEN-DNHENQYVAPRSDAERQLAAIW----- 2052
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
+VL + G + F+ELGG+SL + ++++R + + + A T+
Sbjct: 2053 -----ASVLNLSQVG---ITDDFFELGGHSLLATQVVSRIRKQLNVDMALRTLFEAPTIE 2104
Query: 553 EVLSKMSTDPNGGADSKEATFTAVPMR 579
++L ++ST P + AT T M+
Sbjct: 2105 QLLPRLSTSPVVTLSAITATNTGSGMK 2131
Score = 179 bits (435), Expect = 3e-43
Identities = 133/445 (29%), Positives = 213/445 (47%), Gaps = 29/445 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ALL TW AGA YVPM+P +P R+ H+L+D++ + ++ + F + V +
Sbjct: 546 VAALLGTWMAGAHYVPMDPGYPHARLLHMLQDSK-ARILLSERPHVQAFSAAAVQIVLLD 604
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E+ P ++ P+ + + A V+YTSGSTG+PKGV++ + A+ N L
Sbjct: 605 EV--------QSNPRPSDIRHPVAALNTAYVIYTSGSTGLPKGVQVPHRAVVNFL-LSMT 655
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P ++ + + T+++F SV E++ PL+ G +L++ E D Q L+ + V
Sbjct: 656 NQPGINAGDRLLAVTSISFDISVLELFLPLISGASLVLADSEAAADGQALIKLAMHQDVT 715
Query: 200 TLLRSILMYLALGPASRPLRRLKLWV-CSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + Y + A P LKL V C GE L LA K D + N YG T
Sbjct: 716 FIQATPSNYWLMLEAGWP-STLKLKVLCGGEALPPVLAQ---KLLQRSD--SVWNMYGPT 769
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + GS +GRP+ N + +LDE PGE+ + G +A
Sbjct: 770 ETTIWSAISRVTGS-------ASTLGRPIANTVLRVLDENARLCATGSPGELHIGGEGVA 822
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A +F +P+A+ R+Y+TGD L G + + GR D QVK+RG R+
Sbjct: 823 RGYLDRADLTAQKFVPDPYAS-GSGARIYKTGDLVRWLPNGEIEFLGRIDHQVKVRGFRI 881
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E L P V + V+ G+ +I+ ++ + + L L Y
Sbjct: 882 ELGEIETRLVSFPSVRQGAVIVREDQPGDQQIVAYLLVGEQYAAEPEQLRHHLAQTLPGY 941
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGL 459
M+P + +E PL NGK+DR+ L
Sbjct: 942 MIPNHFVVLEQFPLTPNGKLDRKRL 966
>UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4;
Bacillus|Rep: Bacillomycin D synthetase C - Bacillus
subtilis
Length = 2619
Score = 219 bits (534), Expect = 3e-55
Identities = 160/550 (29%), Positives = 273/550 (49%), Gaps = 48/550 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ + KAG AYVP++P +P+ R+ +IL+D++ L++ + + + VPF +
Sbjct: 326 IVGIFGILKAGGAYVPIDPGYPEERVRYILEDSDTKLLLVQNQS------QERVPFTG-K 378
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + ++ + E A D +A V+YTSGSTG PKGV + + ++ NRL W
Sbjct: 379 VLDMKNPQNFCEDGSNVEPAAG--PDHLAYVIYTSGSTGKPKGVMVEHRSVINRLVWMQE 436
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
+P D + + KTA+TF SV E++ + G L++L ++P+ +++ +
Sbjct: 437 KYPL-DERDAILQKTAITFDVSVWELFWWTISGSRLVLLPNGGEKNPELILDTIAQKGVS 495
Query: 194 RLVLVPTLLRSILMYLALGPA---SRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
+ VP +L + L + P+ + L L+ SGE L + F + +
Sbjct: 496 TMHFVPAMLHAFLESMDQKPSGMLKQKLASLRHVFASGEALKPVHVAGFKHIITSVSQAQ 555
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRD-SEPGE 309
+ N YG TE DV+Y+ + + Y +IPIG+P+ N +Y+L +L + GE
Sbjct: 556 IINLYGPTEATIDVSYFDCQTE---ETYASIPIGKPISNIQLYILHADLEHMQPIGVAGE 612
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
+ +AG LA GY+ A +F ++P A+ +R+YRTGD L G + Y GR D
Sbjct: 613 LCIAGDGLARGYLNRPELTAEKFVNHPIASG---ERIYRTGDLARWLPDGNIEYLGRIDH 669
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVKIRG+R+++ EVE A Q+P + + +V+ +D G + + T + +A +
Sbjct: 670 QVKIRGYRIEIGEVEGAFFQLPVIKEAIVIAREID-GETSLCAYYTAQHA--LTAGELRE 726
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXX 485
+L L YM+P +++E +PL NGK+DR+ L EN + +++
Sbjct: 727 ELSRQLPSYMIPAYFVQLEEMPLTFNGKIDRKSLPSPRENLTGMNYEAPQTELE------ 780
Query: 486 XXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDF 545
+VLG G + F+ELGG+S+ SI ++L GY EI
Sbjct: 781 ------KILAAVWESVLGLERVG---ISDHFFELGGDSIKSIQVSSRLYQAGYKFEIKHL 831
Query: 546 LGASTLGEVL 555
T+ E++
Sbjct: 832 FKYPTISELV 841
Score = 167 bits (405), Expect = 1e-39
Identities = 127/449 (28%), Positives = 228/449 (50%), Gaps = 31/449 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG YVP++P +P+ RI ++L+D+ S+++ G + S
Sbjct: 1848 VIGILAILKAGGVYVPIDPDYPKERIHYMLEDSNVSILLLQHHL------LEGTDYQSHT 1901
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +S+ A+ + P + +A V+YTSG+TG PKG + + + L+
Sbjct: 1902 VFLDDPSSYGAETSNLNLNVMP---NQLAYVIYTSGTTGNPKGTLIEHKNVVRLLFNNKN 1958
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F ++ S+ ++ + F SV E++G LL+G L+I+ ++ ++P++ + + + V
Sbjct: 1959 VFDFNASDTWTLFHS-FCFDFSVWEMYGALLYGGKLVIVPKQIAKNPERYLQLLKSEAVT 2017
Query: 200 TLLRSILMYLALGPASR--PLRRLKLW--VCSGETLSKELASEF-FKYFGNEDGYKLANF 254
L ++ + L R P L + + GE L+ ++ KY + L N
Sbjct: 2018 ILNQTPSYFYQLMQEERADPESNLNIRKIIFGGEALNPSFLKDWKLKYPLTQ----LINM 2073
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE VTY + ++D + IG+P+ Y+LDE PGE++VAG
Sbjct: 2074 YGITETTVHVTYKEIT-EREIDEGRS-NIGQPIPTLQAYILDEYQHIQVMGIPGELYVAG 2131
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
LA GY+ A +F ++P A +++Y+TGD L G + Y GR D QVKIR
Sbjct: 2132 EGLARGYLNRPELTAEKFVEHPFAAG---EKMYKTGDVARWLPDGNIEYLGRIDHQVKIR 2188
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G+R+++ EVE AL Q V + VV+ + G+ ++ +++ T+ ++ L +
Sbjct: 2189 GYRIEIGEVEAALLQSESVKEAVVIAIE-EEGSKQLCAYLSGDDSLNTA--QLKRHLLNK 2245
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P +++E +P+ NGK++R+ L
Sbjct: 2246 LPAYMIPAYFVQMEKMPITANGKIERKAL 2274
>UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces
filamentosus|Rep: Peptide synthetase 2 - Streptomyces
filamentosus (Streptomyces roseosporus)
Length = 7338
Score = 218 bits (532), Expect = 5e-55
Identities = 177/539 (32%), Positives = 251/539 (46%), Gaps = 41/539 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA K+GAAYVP++P +P R+ ++ DA P V+ + VP +
Sbjct: 6309 VVALLAVVKSGAAYVPLDPEYPADRLAYMAGDAAPVAVLTRGDVE----LPGSVPRIGLD 6364
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ AT +A P+T A ++YTSGSTG PKGV +S+ AI NRL W
Sbjct: 6365 DTEIRATLATAPGTNPG---TPVTEAHPAYMIYTSGSTGRPKGVVVSHGAIVNRLAWMQA 6421
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER-LVL 197
+ ++ + + KT F SV E + PLL G L+ RD L IER +
Sbjct: 6422 EYRLDATDRV-LQKTPAGFDVSVWEFFWPLLEGAVLVFARPGGHRDAAYLAGLIERERIT 6480
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L P + L+ +CSGE L +LA +F L N YG
Sbjct: 6481 TAHFVPSMLRVFLEEPGAALCTGLRRVICSGEALGTDLAVDFRAKLP----VPLHNLYGP 6536
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ E + T+PIGRP+ N Y+LD L P PGE+++AGA L
Sbjct: 6537 TEAAVDVTHHAYEPATGT---ATVPIGRPIWNIRTYVLDAALRPVPPGVPGELYLAGAGL 6593
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHR 374
A GY G A RF P E R+YRTGD V G + + GR D QVK+RG R
Sbjct: 6594 ARGYHGRPALTAERFVACPFGVPGE--RMYRTGDLVRWRVDGTLEFVGRADDQVKVRGFR 6651
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT-KPGARTSAQHIEGKLRSALT 433
V+L EVE A+A P V + VV+ G+ ++ +VT G I G + L
Sbjct: 6652 VELGEVEGAVAAHPDVVRAVVVVREDRPGDHRLVAYVTVGGVGGDGLRSAISGLVAERLP 6711
Query: 434 HYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P V+ ++ IPL NGKVDR GL V+V C+
Sbjct: 6712 AYMVPSAVVVLDEIPLTPNGKVDRAGL----------PVPVVSVAGFCAPSSPREEVLCG 6761
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
+G + + GF++LGG+S+ SI + + R G + + D T+
Sbjct: 6762 LFAEVLGV-------ERVGVDDGFFDLGGDSILSIQLVARARRAGLELSVRDVFEGRTV 6813
Score = 189 bits (461), Expect = 2e-46
Identities = 169/537 (31%), Positives = 251/537 (46%), Gaps = 46/537 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA K+GAAYVP++P +P R+ H++ DA P +V+ S D + VP +
Sbjct: 2655 IVALLAVLKSGAAYVPLDPEYPAERLVHMVTDAAPVVVV--TSTDVRTLRT--VPRVELD 2710
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A AT +A P + +++ A V+YTSGSTG PKGV +S+ ++ N L W
Sbjct: 2711 DEATRATLVAA--PATGPDVK-MSASHPAYVIYTSGSTGRPKGVVISHGSLANFLAWARE 2767
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ V T+L+F SV E++ PL G + E R+ LV+
Sbjct: 2768 DLGAERLRHV-VLSTSLSFDVSVVELFAPLSCGGTV-----EIVRNLLALVDRPGRWSAS 2821
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + L A + + +GE LS A + + G ++ANFYG TE
Sbjct: 2822 LVSGVPSAFAQLLEAGLDRADVGMIALAGEALS---ARDVRRVRAVLPGARVANFYGPTE 2878
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
T Y + P+GRPL N +Y+LD+ L GE++VAG LA
Sbjct: 2879 A----TVYATAWYGDTPMDAAAPMGRPLRNTCVYVLDDGLRVVPVGVVGELYVAGVGLAR 2934
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRVD 376
GY+G G A RF P + E R+YRTGD V G + + GR D QVK+RG RV+
Sbjct: 2935 GYLGRVGLTAERFVACPFGARGE--RMYRTGDLVRWRVDGTLEFVGRADDQVKVRGFRVE 2992
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGKLRSALTHY 435
L EVE A+A P V + VV+ G+ ++ +VT G +SA + + L Y
Sbjct: 2993 LGEVEGAVAAHPDVVRAVVVVREDRPGDHRLVAYVTGVDTGGLSSA--VMRAVAERLPAY 3050
Query: 436 MMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P V+ ++ IPL NGKVDR GL V+V C+
Sbjct: 3051 MVPSAVVVLDEIPLTPNGKVDRAGL----------PVPVVSVAGFCAPSSPREEVLCGLF 3100
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
+G + + GF++LGG+S+ SI + + R G + + D T+
Sbjct: 3101 AEVLGV-------ERVGVDDGFFDLGGDSILSIQLVARARRAGLELSVRDVFEGRTV 3150
Score = 181 bits (441), Expect = 6e-44
Identities = 138/451 (30%), Positives = 214/451 (47%), Gaps = 25/451 (5%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+LA KAGAAY+P++ P R+T IL DA P++V+ +A P + S
Sbjct: 519 SVVAILAVLKAGAAYLPLDMDQPAERLTGILADAHPTVVLTTTTATPLPHPGRTLVLDS- 577
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A+ + A DA+ PL + + A +++TSGSTG PKGV + + ++ N
Sbjct: 578 PTTARALAAAPAHNLTDADRRTPLNARNAAYIIHTSGSTGRPKGVVIEHRSLANLFHDHR 637
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLL---HGRALLILSRETTRDPQK---LVNI 192
R + K LT S W L+ G L ++ +T RD ++ L++
Sbjct: 638 RALIEPHAAGGSRLKAGLTASLSFDTSWEGLICLAAGHELHLIDDDTRRDAERVAELIDR 697
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+R+ ++ + G ++ GE + +L + + G
Sbjct: 698 QRIDVIDVTPSFAQQLVETGILDEGRHHPAAFMLGGEGVDAKLWTRL----SDVPGVTSY 753
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N+YG TE D + + + P IG PLDN A Y+LD L P + GE+++
Sbjct: 754 NYYGPTEFTVDAL------ACTVGIAPRPVIGHPLDNTAAYILDGFLRPVPEGVAGELYL 807
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVK 369
AG LA GY G G A RF P E R+YRTGD G V+ Y GR D Q+K
Sbjct: 808 AGTQLARGYAGRPGLTAERFVACPFGAPGE--RMYRTGDLVRRSPGGVVEYLGRVDDQIK 865
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++ E+E ALA P V + VVL + G ++ +V PG + + G L
Sbjct: 866 LRGFRIEPAEIELALAGHPAVAQNVVLLHRSATGEARLVAYVV--PGTPVDPRELTGHLA 923
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ L YM+P + ++++PL NGK+DR L
Sbjct: 924 ARLPAYMVPSAFVLLDTLPLTPNGKLDRGAL 954
Score = 169 bits (412), Expect = 2e-40
Identities = 146/446 (32%), Positives = 209/446 (46%), Gaps = 27/446 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA K GA ++P++P FP R++++L DA P++V+ + + S V S E
Sbjct: 5254 LVALLAVQKTGAGHLPLDPGFPAERLSYMLDDARPAVVLTTEDISARIPGGSHVVLDS-E 5312
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ E H A P A A V+YTSGSTG PKGV + +A+ N L
Sbjct: 5313 QVTGELHDHPATSPAGRGNPA-----GPAYVIYTSGSTGQPKGVVVPSAALVNFLADMVP 5367
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL-VNIERLVLV 198
+ + + T + F + E++ PLL G +++ ET RDP E +
Sbjct: 5368 RLGLRGGDRL-LSVTTVGFDIAALELFVPLLSGATVVLADGETVRDPALARQTCEDHGVT 5426
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ L A LR + V GE LS L + + N YG T
Sbjct: 5427 MVQATPSWWHGMLADAGDSLRGVHA-VVGGEALSPGLRDALTR-----GARSVTNMYGPT 5480
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + G D P IG P+ N +Y+LD L GE+++AG LA
Sbjct: 5481 ET---TIWSTSAGQAAGDSAPP-SIGTPILNTRVYVLDAALCVVPPGVAGELYIAGDGLA 5536
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
GY+G G A RF P E R+YRTGD V GA+ + GR D QVK+RG RV
Sbjct: 5537 RGYLGRAGLTAERFVACPFGAPGE--RMYRTGDLVRWRVDGALEFVGRADDQVKVRGFRV 5594
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGKLRSALTH 434
+L EVE A+A P V + VV+ G+ ++ +VT G +SA + + L
Sbjct: 5595 ELGEVEGAVAAHPDVVRAVVVVREDRPGDHRLVAYVTGVDTGGLSSA--VMRAVAERLPA 5652
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM+P V+ ++ IPL NGKVDR L
Sbjct: 5653 YMVPSAVVVLDEIPLTPNGKVDRAAL 5678
Score = 149 bits (361), Expect = 3e-34
Identities = 137/453 (30%), Positives = 209/453 (46%), Gaps = 29/453 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG YVP++P +P R+ +L DA LV+ + + G F
Sbjct: 4182 VVMLLAVAKAGGFYVPVDPEWPVERVGWVLADAGVGLVVVGEGLSHVVGDFPGGEVFEFS 4241
Query: 80 ELAQE--------ATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAIC 131
+ +E A D E + L V+YTSGSTG PKGV ++++++
Sbjct: 4242 RVVRESCLVELVAADGVEVRNVTDGERASRLLPGHPLYVVYTSGSTGRPKGVVVTHASVG 4301
Query: 132 NRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN 191
L + R + ++L F +V ++ PL+ G +++ E Q V
Sbjct: 4302 GYLA-RGRDVYAGAVGGVGFVHSSLAFDLTVTVLFTPLVSGGCVVL--GELDESAQG-VG 4357
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ + P+ L LG + + + GE LS E+ + G +
Sbjct: 4358 ASFVKVTPSHLG------LLGELEGVVAGNGMLLVGGEALSGGALREWRE---RNPGVVV 4408
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE+ + +++ +++ P +PIGRP +++LD L GE++
Sbjct: 4409 VNAYGPTELTVNCAEFLIAPGEEVPDGP-VPIGRPFAGQRMFVLDAALRVVPVGVVGELY 4467
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
VAG LA GY+G G A RF P E R+YRTGD V GA+ + GR D QV
Sbjct: 4468 VAGVGLARGYLGRVGLTAERFVACPFGVPGE--RMYRTGDLVRWRVDGALEFVGRADDQV 4525
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT-KPGARTSAQHIEGK 427
K+RG RV+L EVE A+A P V + VV+ G+ ++ +VT G I G
Sbjct: 4526 KVRGFRVELGEVEGAVAAHPDVVRAVVVVREDRPGDHRLVAYVTAGGVGGDGLRSAISGL 4585
Query: 428 LRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
+ L YM+P V+ ++ IPL NGKVDR L
Sbjct: 4586 VAERLPAYMVPSAVVVLDEIPLTPNGKVDRAAL 4618
Score = 148 bits (359), Expect = 5e-34
Identities = 137/453 (30%), Positives = 211/453 (46%), Gaps = 31/453 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG YVP++P +P R+ +L DA LV+ + + G F
Sbjct: 1591 VVMLLAVAKAGGFYVPVDPEWPVERVGWVLADAGVGLVVVGEGLSHVVGDFPGGEVFEFS 1650
Query: 80 ELAQE--------ATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAIC 131
+ +E A D E + L V+YTSGSTG PKGV ++++++
Sbjct: 1651 RVVRESCLVELVAADGVEVRNVTDGERASRLLPGHPLYVVYTSGSTGRPKGVVVTHASVG 1710
Query: 132 NRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN 191
L + R + ++L F +V ++ PL+ G +++ E Q V
Sbjct: 1711 GYLA-RGRDVYAGAVGGVGFVHSSLAFDLTVTVLFTPLVSGGCVVL--GELDESAQG-VG 1766
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ + P+ L LG + + + GE LS E+ + G +
Sbjct: 1767 ASFVKVTPSHLG------LLGELEGVVAGNGMLLVGGEALSGGALREWRE---RNPGVVV 1817
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE+ + +++ +++ P +PIGRP +++LD L GE++
Sbjct: 1818 VNAYGPTELTVNCAEFLIAPGEEVPDGP-VPIGRPFAGQRMFVLDAALRVVPVGVVGELY 1876
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
VAG LA GY+G G A RF P E R+YRTGD V GA+ + GR D QV
Sbjct: 1877 VAGVGLARGYLGRAGLTAERFVACPFGAPGE--RMYRTGDLVRWRVDGALEFVGRADDQV 1934
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGK 427
K+RG RV+L EVE A+A P V + VV+ G+ ++ +VT G +SA +
Sbjct: 1935 KVRGFRVELGEVEGAVAAHPDVVRAVVVVREDRPGDHRLVAYVTGVDTGGLSSA--VMRA 1992
Query: 428 LRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
+ L YM+P V+ ++ IPL NGKVDR L
Sbjct: 1993 VAERLPAYMVPSAVVVLDEIPLTPNGKVDRAAL 2025
>UniRef50_Q0S5D8 Cluster: Non-ribosomal peptide synthetase; n=2;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 6063
Score = 218 bits (532), Expect = 5e-55
Identities = 158/450 (35%), Positives = 226/450 (50%), Gaps = 25/450 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A KAG AYVP++P P RI +++ A P +V+ +AD + + VP +
Sbjct: 2098 LVGIYAVIKAGGAYVPIDPDQPAERIAYVVATAGP-IVVLTMTAD-RVALPAEVPAVDLD 2155
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L A S D+P+ D + L PL + + A V++TSGSTG PKGV + + I NRL W
Sbjct: 2156 TLDVSALS---DDPVRDRDRLGPLHTRNPAYVIFTSGSTGRPKGVAVPHEGIVNRLLWMQ 2212
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+P SD +++ + KT +TF SV E++ PL G L+I + RDP L + R V
Sbjct: 2213 HRYPLSD-DDVVLHKTPVTFDVSVWELFWPLQTGARLVIAEPDGHRDPAYLERVIRAESV 2271
Query: 199 PTL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
T+ + S+L G L+ SGE L A+ + E L N YG
Sbjct: 2272 TTVHFVPSMLAVFLAGAHVDGCSSLRRVFTSGEALPPMTAAALHRASEAE----LHNLYG 2327
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DVTYY G D+ T+PIG P+ N Y+LD L P GE+++ G
Sbjct: 2328 PTEASVDVTYYE-TGPDE----TTVPIGAPIWNTQTYVLDGRLQPVPVGVAGELYLGGVQ 2382
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQ---RLYRTGDF-GTLVKGAVLYAGRTDAQVKI 370
LA GY G A+RF NP + RLYRTGD L G + Y GRTD QVK+
Sbjct: 2383 LARGYQGRSDLTADRFVANPFVAAGNVRVGSRLYRTGDLVRWLPTGQLEYLGRTDFQVKL 2442
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L ++E AL + V + V L + G+V PG + + + +
Sbjct: 2443 RGQRIELGDIEAALLRHGDVAQAVALVRNDGSTGDYLAGYVVPAPGRSPAERAVLDFAAA 2502
Query: 431 ALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
L YM+P + V +PL NGK+DR+ L
Sbjct: 2503 TLPRYMVPSALVVLAQLPLTANGKLDRKAL 2532
Score = 203 bits (495), Expect = 2e-50
Identities = 152/448 (33%), Positives = 231/448 (51%), Gaps = 26/448 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++ KAGA Y+P++P P R +++ A+P +V+ S D + V +
Sbjct: 4220 MVSIYGVLKAGAGYLPLDPEHPAHRTEYVMATAKP-VVVLTTSRDRDDLP-AAVDAVEVD 4277
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + A+ DA LAPL +++A ++TSGSTG PKGV +S+ ++ N++ W
Sbjct: 4278 VL--DLSVFDAEAVTDASRLAPLRPENLAYAIFTSGSTGRPKGVAVSHRSVVNQIAWMRS 4335
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ D + + + KT +TF SV E++ PL G L+I + RDP+ L+ + V
Sbjct: 4336 RYALGDRDTV-LHKTPITFDASVWELFYPLQVGARLVIAAPGGHRDPEYLMRMSDRWHV- 4393
Query: 200 TLLRSILMYLALGPASRPL---RRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
T+L + LAL A L R L+ GE L ELA+ F L N YG
Sbjct: 4394 TILEFVPSMLALFLAESSLALPRSLRYVSVGGEALPSELAARF----AARTEAVLDNTYG 4449
Query: 257 STEVMGDVTYY-VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TEV T + L G+ IPIGRP+ N ++LD L PGE+++AG
Sbjct: 4450 PTEVTVTSTVHRCLAGASG-----PIPIGRPIRNTRTFVLDRRLHRVPVGVPGELYLAGI 4504
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
LA GY G A RF +P A E RLYRTGD G + Y GRTD QVK+RG
Sbjct: 4505 QLARGYHARGALTAERFVAHPFADSGE--RLYRTGDLVRWNSNGDLEYLGRTDFQVKLRG 4562
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+E AL VD+ VV+ + G +++G+V G + + ++L
Sbjct: 4563 LRIELGEIETALTADESVDQAVVVVRDGEFGQ-QLVGYVLPTRGRTVDVEATREVVSTSL 4621
Query: 433 THYMMPQVIEV-ESIPLLVNGKVDRQGL 459
+YM+P V+ V +++PL +GK+DR+ L
Sbjct: 4622 PNYMVPDVLVVLDALPLNPSGKLDRRAL 4649
Score = 189 bits (461), Expect = 2e-46
Identities = 136/446 (30%), Positives = 223/446 (50%), Gaps = 23/446 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ + A + GAA+VP++P P R +IL+ P V+ S F S + +
Sbjct: 5278 VTGIYAVLRTGAAFVPLDPDQPPARNDYILETTGPVCVL---STARDGFDTSRNRVLNID 5334
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + + +S++ ++E + +++A V++TSGSTG PKGV +S+ AI N++ W
Sbjct: 5335 --APDLSVYSSEPVGESEVVTSARPENLAYVIFTSGSTGRPKGVSVSHRAIVNQMAWLAA 5392
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ DS ++ V KT +TF S+ E+ PL G +++ + RDP L+++ + V
Sbjct: 5393 EYELGDS-DVVVQKTPVTFDVSMWELLVPLAVGARMIVARPDGHRDPDYLLSLMQDSGVT 5451
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + S+L L P + L+ GE L EL+ + +L N YG
Sbjct: 5452 VAAFVPSMLATLLADPEAFLPDSLRCVFAGGEELPVELSGR----CASRSKARLDNKYGP 5507
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T + +G ++ ++PIG P+ N +LD L P GE+++AG L
Sbjct: 5508 TEYAVTATSHRCDGLER----ESVPIGEPVWNTTALVLDRRLHPVPIGVEGELYLAGVQL 5563
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
+ GY G A RF +P RLYRTGD +G ++Y GR D+QVK+RG R
Sbjct: 5564 SRGYHRRQGLTAERFVADPFGAAG--TRLYRTGDVVKWNPRGQLMYLGRLDSQVKVRGLR 5621
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E AL + + VV+ + D G +++G+V + G + + +L
Sbjct: 5622 IELGEIETALVAQQTIAQAVVIVHDGDFGQ-QLVGYVVPEGGRLVDVESVRATAGRSLPQ 5680
Query: 435 YMMPQVIEV-ESIPLLVNGKVDRQGL 459
YM+P V+ V + +PL +GK DR L
Sbjct: 5681 YMVPDVLMVLDQLPLTASGKFDRNAL 5706
Score = 152 bits (369), Expect = 3e-35
Identities = 125/448 (27%), Positives = 221/448 (49%), Gaps = 28/448 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESG-VPFAS 77
+++++ A K G +VP++P P RI H+L D+ + + K + VP A
Sbjct: 3164 SVVSVWAVVKTGGGFVPVDPKLPVERIEHMLVDSGAVIGLTSAETTSLPGKVAWLVPTAG 3223
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E+ + S+ E DAE AP+T + A ++YTSGSTG+PKGV ++++ + +
Sbjct: 3224 --EVQELCDGFSSAEITDAERRAPVTWTNAAYMIYTSGSTGVPKGVVVAHAGLASFCADA 3281
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ--KLVNIERL 195
+ + + ++ +F SV E+ G L++ E + +L+ +ER+
Sbjct: 3282 RLELNLTGNSRVLRLSSS-SFDASVFEMIAGFSAGATLVVAPPEIIGGSELAELLRVERV 3340
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ T ++ + + P L L+ V G+ EL ++F + + N Y
Sbjct: 3341 THIITAPAALGI---VDPGG--LDELQAVVVGGDVCPPELVAKFAPFC------RFYNSY 3389
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T ++ ++ L I IG P++ +LD L P+ GE++++G
Sbjct: 3390 GPTE-----TTIIISMTEALVPEERITIGTPIEGAGAVVLDARLHPSPVGVIGELYLSGR 3444
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRG 372
LA GY G A RF NP E R+YRTGD + G + + GR D+QV++RG
Sbjct: 3445 GLARGYHARGALTAARFVANPFGGSGE--RMYRTGDLVRWTRDGRLDFVGRIDSQVQLRG 3502
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+E AL++ GV + VV+ +++G+V A + + ++ L
Sbjct: 3503 LRIELGEIEAALSRCEGVAQTVVVLRHDPHTGEQLVGYVVADSKAALDPEALRIRVGETL 3562
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGL 459
+YM+P +V+ V+++PL +GK+DR+ L
Sbjct: 3563 PNYMVPSRVMVVDALPLNPSGKLDRRAL 3590
Score = 136 bits (329), Expect = 2e-30
Identities = 121/453 (26%), Positives = 202/453 (44%), Gaps = 29/453 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A A K GAA+VP++P P R+ H+L D+ + + ++
Sbjct: 546 SLVAFWAVAKTGAAFVPVDPKLPPERVAHMLSDSGALVGLTLHELRATLPDGIHWLVVDD 605
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+E+ DA+ APL+ A ++YTSGSTG+PKGV ++++ + N
Sbjct: 606 DEVRARCDRQRRAAIGDADRRAPLSVHHPAYMIYTSGSTGLPKGVVVTHTGLSNFAAGAR 665
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
D + + +A +F SV E+ G +++ E LV++ V
Sbjct: 666 PELGVHDESRMLRFSSA-SFDASVFEMIQAFSAGATMVVAPPEV-HGGSDLVDLLSEQQV 723
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
++ + + + P R L L+ V G+ + +L F + + N YG T
Sbjct: 724 THIITAPTVMNTVDP--RGLEHLEAVVVGGDVCTPDLVERFGQVC------RFTNSYGPT 775
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T + G + P I IGRP+ ++ +LD +L GE+++AG +A
Sbjct: 776 ET----TIIITAGEPLMPGEP-ITIGRPIQGTSVVVLDRKLRAVPAGVVGELYLAGPGIA 830
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGA---------VLYAGRTDAQ 367
GY G ANRF NP +P RLYRTGD V+ + + + GR+D Q
Sbjct: 831 RGYHHRHGLTANRFVANPFG-EPG-SRLYRTGDEVRWVRSSQGTEAGHYTLEFIGRSDTQ 888
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR-TSAQHIEG 426
VKIRG R++L E++ AL GV+ + + G ++ +V G +EG
Sbjct: 889 VKIRGFRIELGEIDSALLAQDGVNFAATVVHRTAGGTTALVSYVRLDTGREFDPVAIVEG 948
Query: 427 KLRSALTHYMMPQVIEVESIPLLVNGKVDRQGL 459
+H + V+ +E +P+ GK+DR L
Sbjct: 949 VAEIVPSHMIPSAVMRLEHVPVTAAGKLDRSAL 981
>UniRef50_A4C379 Cluster: Non-ribosomal peptide synthetase, terminal
component; n=1; Pseudoalteromonas tunicata D2|Rep:
Non-ribosomal peptide synthetase, terminal component -
Pseudoalteromonas tunicata D2
Length = 3345
Score = 217 bits (530), Expect = 9e-55
Identities = 171/555 (30%), Positives = 275/555 (49%), Gaps = 48/555 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM-FKESGVPFASF 78
++ + KAG AYVP++P P R+ +++ D + ++V+ + + E+ V +
Sbjct: 606 VIGIWGILKAGGAYVPLDPELPSARLQYLVSDTQANVVLSTQALKEHITLGEAQVVY--L 663
Query: 79 EELAQEAT---SHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
+ L + T S ++E ++ + + LTS +A ++YTSGSTG PKGV L++ A+ NR+
Sbjct: 664 DGLGSQVTHPFSEYSEENINLKEIG-LTSQHLAYMIYTSGSTGQPKGVLLAHQALHNRID 722
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------ 189
W R + DS ++ + KT +F SV E P+L G L++ + +DP L
Sbjct: 723 WMDREYG-CDSLDVILQKTPYSFDVSVWEFIWPMLKGAKLVVAKPQGHKDPSYLTELIVA 781
Query: 190 VNIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
+ +L VP++L +L + L R + LK CSGE L E F++ E G
Sbjct: 782 TGVTKLHFVPSMLGVMLAHGDL----RRCQSLKQVFCSGEALQISHV-EQFRHQLPEVG- 835
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
L N YG TE DV+Y+ + S L ++PIG+P+ N +Y+LD+EL+ GE
Sbjct: 836 -LHNLYGPTEAAIDVSYW--DCSQPLG--SSVPIGKPIQNIQLYILDDELNLLPQGACGE 890
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPE---FQRLYRTGDFGTLVK-GAVLYAGR 363
+ + G LA GY+ RF NP E +RLY+TGD + G + Y GR
Sbjct: 891 LHIGGDGLARGYLNRPELTQERFIANPFYQAEEGNSSERLYKTGDLVRYKEDGNIEYMGR 950
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ- 422
D QVKIRG R++L E+E +AQ +D +V+ GN ++ + T +
Sbjct: 951 LDHQVKIRGFRIELGEIEYQVAQHKQIDSALVVAQADKAGNQRLIAYAKTVQADASKEDV 1010
Query: 423 --HIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDID 479
++ +L + L YM+P VI V PL NGK+DR+GL + E+ ID
Sbjct: 1011 IASLKAELAAVLPEYMVPANVILVSEWPLTPNGKIDRRGLPSVDES------------ID 1058
Query: 480 CSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYY 539
S + A L R + +S+ + F+ELGG+SL + +++L+ RG+
Sbjct: 1059 -STAYVAPHGETELMLVEICAELLRINKLEISIMANFFELGGHSLMIMDLVSRLKKRGFS 1117
Query: 540 VEISDFLGASTLGEV 554
+ A L E+
Sbjct: 1118 TSVQSLFAAKVLKEM 1132
Score = 204 bits (499), Expect = 5e-51
Identities = 152/469 (32%), Positives = 242/469 (51%), Gaps = 35/469 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM-FKESGVPFASF 78
++ + KAG AYVP++P P R+ +++ D + ++V+ + + E+ V +
Sbjct: 2790 VIGIWGILKAGGAYVPLDPELPSARLQYLVSDTQANVVLSTQALKEHITLGEAQVVY--L 2847
Query: 79 EELAQEAT---SHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
+ L + T S ++E ++ + + LTS +A ++YTSGSTG PKGV L++ A+ NR+
Sbjct: 2848 DGLGSQVTHPFSEYSEENINLKEIG-LTSQHLAYMIYTSGSTGQPKGVLLAHQALHNRID 2906
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------ 189
W R + DS ++ + KT +F SV E P+L G L++ + +DP L
Sbjct: 2907 WMDREYG-CDSLDVILQKTPYSFDVSVWEFIWPMLKGAKLVVAKPQGHKDPSYLTELIVA 2965
Query: 190 VNIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
+ +L VP++L +L + L R + LK CSGE L E F+Y E G
Sbjct: 2966 TGVTKLHFVPSMLGVMLAHGDL----RRCQSLKQVFCSGEALQISHV-EQFRYQLPEVG- 3019
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
L N YG TE DV+Y+ + S L ++PIG+P+ N +Y+LD+EL+ GE
Sbjct: 3020 -LHNLYGPTEAAIDVSYW--DCSQPLG--SSVPIGKPIQNIQLYILDDELNLLPQGACGE 3074
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPE---FQRLYRTGDFGTLVK-GAVLYAGR 363
+ + G LA GY+ RF NP E +RLY+TGD + G + Y GR
Sbjct: 3075 LHIGGDGLARGYLNRPELTQERFIANPFYQAEEGNSSERLYKTGDLVRYKEDGNIEYMGR 3134
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGF---VTTKPGARTS 420
D QVKIRG R++L E+E +AQ +D +V+ GN ++ + V +
Sbjct: 3135 LDHQVKIRGFRIELGEIEYQVAQHKQIDSALVVAQADKAGNQRLIAYGKTVQAEASKEDV 3194
Query: 421 AQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNN 468
++ +L + L YM+P VI V PL NGK+DR+GL + E+ ++
Sbjct: 3195 IASLKAELAAVLPEYMVPANVILVSEWPLTPNGKIDRRGLPSVDESIDS 3243
Score = 194 bits (472), Expect = 1e-47
Identities = 170/560 (30%), Positives = 272/560 (48%), Gaps = 50/560 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AYVP++P++PQ R+ I DA LV+ ++ +
Sbjct: 1701 MVGILAILKAGGAYVPLDPTYPQERLNFIFDDASLDLVLTQSCLCNTLTLDDNKLLCLDS 1760
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A + ++LA LT+ +A V+YTSGSTG PKGV S+ + +
Sbjct: 1761 AQLESALVCYPTSNISKDSLA-LTAAHLAYVIYTSGSTGQPKGVLQSHENVRRLFYVTQP 1819
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLV 196
F ++ + CV+ + F SV E+WG L +G LL+ + + +D + + + E+L
Sbjct: 1820 DFNFTAQDCWCVFHS-YAFDFSVWEMWGALFYGGKLLVPTLDEVKDTRLFIELCHKEKLT 1878
Query: 197 LV---PTLLRSILMYL-ALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
++ P+ + + YL ++G A LR + V GE L + + +++ F + +L
Sbjct: 1879 ILNQTPSAFKQLTEYLVSIGQALPTLRTI---VFGGEGLVESHLALWWQNFADHSA-ELI 1934
Query: 253 NFYGSTEVMGDVTYYVL-EGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE VTY VL +GS I IG+PL + I LLDE L+ GE++
Sbjct: 1935 NMYGITETTVHVTYKVLGQGS-------RITIGKPLRDQHILLLDESLNLVPKGCAGEIY 1987
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEF---QRLYRTGDFGTL-VKGAVLYAGRTD 365
VAGA LA GY+ A RF NP+ + +RLY+ GD +G + Y GR D
Sbjct: 1988 VAGAGLARGYLNREALSAERFIANPYYHEAGAWLGERLYKAGDLARYDAEGELHYLGRLD 2047
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCY-GLDRGNPEILGFV----TTKPGARTS 420
QVKIRGHR++L EVE + Q+ VD +VL G+D +++ +V T K G
Sbjct: 2048 DQVKIRGHRIELGEVESRITQLEMVDSALVLALPGVD-AQLQLVAYVKVIDTFKEG-DWQ 2105
Query: 421 AQHIEGKLRSALTHYMMPQVI-EVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDID 479
AQ ++ L L YM+P VI + PL NGKVD++ L + T++ +
Sbjct: 2106 AQ-LKQTLSQQLQAYMLPSVIVPITQWPLTNNGKVDKKALPAIETGTDHTN--------- 2155
Query: 480 CSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GY 538
+ + L A + + + F+ELGG+SL + + +R R
Sbjct: 2156 ----FEAPTTATEQTVTEIWSELLNIAVDRIGINTNFFELGGHSLLLMKLLAGIRKRLNR 2211
Query: 539 YVEISDFLGASTLGEVLSKM 558
+ + D A+T+ + +K+
Sbjct: 2212 ELTVKDIFSAATVKQQAAKI 2231
>UniRef50_Q8YTR5 Cluster: Peptide synthetase; n=7;
Cyanobacteria|Rep: Peptide synthetase - Anabaena sp.
(strain PCC 7120)
Length = 2588
Score = 217 bits (529), Expect = 1e-54
Identities = 149/468 (31%), Positives = 236/468 (50%), Gaps = 37/468 (7%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ LL KAG AYVP++P +PQ RI ++L+D++ + + + + +P +
Sbjct: 525 VCLLGIIKAGGAYVPIDPEYPQERIAYMLEDSQVKVFLTQEQL------LAQIPQNQTHK 578
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
+ + + + + D++A V+YTSGSTG PKGV ++ ICNRL W T
Sbjct: 579 ICIDTEWDKISRQPNTNPDSGVKLDNLAYVIYTSGSTGKPKGVMNTHQGICNRLLWMQET 638
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLVL 197
+ + ++ I + KT +F SV E + LL G L+I RD L+N+ E++ +
Sbjct: 639 YQINSTDSI-LQKTPFSFDVSVWEFFWTLLTGARLVIAKPGGHRDSAYLINLIIQEQITI 697
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + + ++L G + LK +CSGE LS +L ++F + F E L N YG
Sbjct: 698 LHFVPSMLRIFLESGNVEK-CTSLKRVICSGEALSLDLQNQFLERFDCE----LYNLYGP 752
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ L T+PIGRP+ N IY+LD+ L P PGE+++ GA +
Sbjct: 753 TEAAIDVTFWQCRKHTNL---KTVPIGRPIANTHIYILDQHLQPVPIGVPGELYIGGAGV 809
Query: 318 AAGYVGG--------------GGANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAG 362
A GY+ G PHA P LY+TGD ++ G + Y G
Sbjct: 810 ARGYLNRPELTAERFISYSDLGSIGYLTPMPHAPCPIPHALYKTGDRARYLRDGTIEYLG 869
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R D QVKIRG R++L E+E L+Q V +V+ G+ ++ ++ ++ T +
Sbjct: 870 RLDNQVKIRGFRIELGEIETVLSQHSEVQAAIVVVTEDTTGDKRLVAYIVSENPEITDLR 929
Query: 423 HIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNN 469
L L YM+P Q I ++++PL NGKVDR+ L K T+++
Sbjct: 930 QY---LAKNLPDYMIPSQFITLDALPLTPNGKVDRRALPKPQFKTSSH 974
Score = 191 bits (466), Expect = 5e-47
Identities = 161/552 (29%), Positives = 254/552 (46%), Gaps = 50/552 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +LA KAG YVP++P++PQ R+ +++DA+ +++ P + +P F+
Sbjct: 1586 IIGILAILKAGGFYVPLDPTYPQERLEFLIEDAQIQVILTQQQHIPQL---PDLPIFCFD 1642
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
T H P++ T +++A V+YTSGSTG+PKGV + + + RL
Sbjct: 1643 TDTANLTQHPTTNPVNHTT-----PENLAYVMYTSGSTGVPKGVCIPHRGVV-RLVKDCN 1696
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
S E I + ++F S EIWG LL+G L+ILS + + I + +
Sbjct: 1697 YINLSADESI-LQAAPISFDASTFEIWGALLNGSRLVILSNQQPTLAEIGQAITQHQITT 1755
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L +L + L+ +K + G+ LS A K ++ N YG TE
Sbjct: 1756 LWLTAGLFHLMVDEHLESLKSVKQLIAGGDVLS---AVHINKLLQTYPECRVINGYGPTE 1812
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ T+ + T+PIGRP++N +Y+LD L+P PGE+++AG LA
Sbjct: 1813 ---NTTFTCCYSVTDICESNTVPIGRPINNTQVYILDNHLNPLPVGVPGELYIAGDGLAR 1869
Query: 320 GYVGGG--GANRFCDNPHAT------QPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GY+ A +F + T LY+TGD L G + Y GR D QVKI
Sbjct: 1870 GYLNQPTLTAEKFINWGLGTGDWGLGTTTLSTLYKTGDRARYLADGNIEYLGRLDNQVKI 1929
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L Q P V +CVV+ R I F+ + ++ L+
Sbjct: 1930 RGFRIELGEIEAVLNQHPAVKECVVIA----REKQLIAYFIALD----NTPDNLREFLQQ 1981
Query: 431 ALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L Y++P + +E++PL VNGKVDRQ L E T+ D DI+
Sbjct: 1982 RLPDYLIPHFFVALETLPLTVNGKVDRQ-KLPAPEITSFPDGTVARSDIEAKLLEIW--- 2037
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
+VL + +S+ F+ LGG+S+ +I I+K G +
Sbjct: 2038 ---------SSVLNLS---QVSIYDNFFALGGDSILAIQLISKANQVGLQLTPKQLFQYQ 2085
Query: 550 TLGEVLSKMSTD 561
T+ E+ + D
Sbjct: 2086 TIAELAGVFTVD 2097
>UniRef50_Q7N5R5 Cluster: Similar to antibiotic synthetase; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Similar to
antibiotic synthetase - Photorhabdus luminescens subsp.
laumondii
Length = 1065
Score = 217 bits (529), Expect = 1e-54
Identities = 167/552 (30%), Positives = 269/552 (48%), Gaps = 33/552 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP+E +PQ R+ ++ DAEP+ VI + +
Sbjct: 523 MVTLLAIIKAGAAYVPVEADYPQSRLDFMIDDAEPACVITTSEIAQRLTANIPMILLDDP 582
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL S + D E L PL S A ++YTSGSTG+PKGV +++ + L R
Sbjct: 583 ELLTYLEMQSVADLSDKERLQPLISAHPAYIIYTSGSTGVPKGVVVTHHNVMRLLQSTQR 642
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP----QKLVNIERL 195
F +S+++ ++ + F +V E WG LL+G L+I+ E +R P Q LV+ +
Sbjct: 643 WFNFSETDCWTMFHS-YAFDFAVWECWGALLNGGRLVIVPWEVSRSPTDFLQLLVSEKVT 701
Query: 196 VL--VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VL P+ ++++ P L+ + GE L+ + E+++ +++ +L N
Sbjct: 702 VLNQTPSAFQALIHADREAPELGQSLVLRTVIFGGEALNAHILEEWYQRH-DDNAPQLVN 760
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIP-IGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE VTY+ L S ++ P IG P+D+ IY+LDE P GE++V
Sbjct: 761 MYGITETTVHVTYFPL--SREVVAQPASSLIGEPIDDLGIYILDEAQHPVPVGFVGEIYV 818
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVK 369
GA +A GY+ A RF +P +YRTGD L + VL + GRTD QVK
Sbjct: 819 GGAGVARGYLNRPELTAERFMADPFIGTDA--HMYRTGDLARLRRDGVLDFLGRTDDQVK 876
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG R++L EV AL P + + V+ + ++G+V G +Q I L
Sbjct: 877 IRGFRIELGEVAAALNAHPDIVQSEVIVREDEGQQKRLVGYVIAHKGITLESQLIRSSLT 936
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
+ L M+P +++++ PL +NGK+DR+ L K N+ V ++ + S
Sbjct: 937 TCLPEAMIPAAIVQLDHFPLTINGKLDRKALPKPMWNS-------VVIN-ESSSSSPQEL 988
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEISDFLG 547
+G +S F+ELGG SL ++ I ++R D G + + D
Sbjct: 989 SLCRLFAELLGL-------ENISPEDNFFELGGESLVAMRVIARVRSDFGVEITLRDLFN 1041
Query: 548 ASTLGEVLSKMS 559
A + +++ +++
Sbjct: 1042 APRVSQLVQRLN 1053
>UniRef50_A4XWA8 Cluster: Amino acid adenylation domain; n=1;
Pseudomonas mendocina ymp|Rep: Amino acid adenylation
domain - Pseudomonas mendocina ymp
Length = 5328
Score = 217 bits (529), Expect = 1e-54
Identities = 157/450 (34%), Positives = 242/450 (53%), Gaps = 40/450 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL A KAG AYVPM+P +P R+ ++L+D+ SL++ D+ S+ + SGV + +
Sbjct: 3081 VVALYAILKAGGAYVPMDPEYPAERLRYMLEDSGVSLLLSHDAVIDSLPQVSGVQVLNLD 3140
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + EP A + + + +A ++YTSGSTG PKG S++A+ NRL W +
Sbjct: 3141 HL------DLSQEPQTAPEV-DIHPEQLAYLIYTSGSTGKPKGAGNSHAALYNRLAWMQQ 3193
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
+ + + + + KT +F SV E + PL+ G L++ RDP KLV IER
Sbjct: 3194 AYHLTADDRV-LQKTPFSFDVSVWEFFWPLITGARLVMAQPGDHRDPAKLVELIEREKIS 3252
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L + + + L L R+ VCSGE L ELAS + + Y N
Sbjct: 3253 TLHFVPSMLAAFVGHGDLHGCD-SLCRI---VCSGEALPAELASSTRQLLPQAELY---N 3305
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ G + ++PIGRP+ N I++LDE L+P GE+++
Sbjct: 3306 LYGPTEAAIDVTHWRCSGQEG----RSVPIGRPIANLQIHILDERLNPQPIGVAGELYIG 3361
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKI 370
G LA GY G A RF +P + QRLYR+GD + VL Y GR D QVK+
Sbjct: 3362 GIGLARGYHRRPGLTAERFVASPFG---DGQRLYRSGDLARWTEEGVLEYLGRIDHQVKL 3418
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E AL + P + + VVL + +++ +V G + +L+
Sbjct: 3419 RGLRIELGEIEAALLEHPALREAVVLV-----RDQQLVAYVV---GGDYDEVELRARLKQ 3470
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +M+P V+++E +PL NGK++R+ L
Sbjct: 3471 RLPEFMLPSHVMQLERLPLSPNGKLERKAL 3500
Score = 215 bits (525), Expect = 4e-54
Identities = 156/450 (34%), Positives = 241/450 (53%), Gaps = 40/450 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL A KAG AYVPM+P +P R+ ++L+D+ SL++ D+ + + SGV + +
Sbjct: 567 VVALYAILKAGGAYVPMDPEYPAERLRYMLEDSGVSLLLSHDAVIDGLPQVSGVQVLNLD 626
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + EP A + + + +A ++YTSGSTG PKG S++A+ NRL W +
Sbjct: 627 HL------DLSQEPQTAPEV-DIHPEQLAYLIYTSGSTGKPKGAGNSHAALYNRLAWMQQ 679
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
+ + + + + KT +F SV E + PL+ G L++ RDP KLV IER
Sbjct: 680 AYHLTADDRV-LQKTPFSFDVSVWEFFWPLITGARLVMAQPGDHRDPAKLVELIEREKIS 738
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L + + + L L R+ VCSGE L ELAS + + Y N
Sbjct: 739 TLHFVPSMLAAFVGHGDLHGCD-SLCRI---VCSGEALPAELASSTRQLLPQAELY---N 791
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ G + ++PIGRP+ N I++LDE L+P GE+++
Sbjct: 792 LYGPTEAAIDVTHWRCSGQEG----RSVPIGRPIANLQIHILDERLNPQPIGVAGELYIG 847
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKI 370
G LA GY G A RF +P + QRLYR+GD + VL Y GR D QVK+
Sbjct: 848 GIGLARGYHRRPGLTAERFVASPFG---DGQRLYRSGDLARWTEEGVLEYLGRIDHQVKL 904
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E AL + P + + VVL + +++ +V G + +L+
Sbjct: 905 RGLRIELGEIEAALLEHPALREAVVLV-----RDQQLVAYVV---GGDYDEVELRARLKQ 956
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +M+P V+++E +PL NGK++R+ L
Sbjct: 957 RLPEFMLPSHVMQLERLPLSPNGKLERKAL 986
Score = 164 bits (398), Expect = 9e-39
Identities = 152/525 (28%), Positives = 251/525 (47%), Gaps = 44/525 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ALLA KAG AYVP++P +P R+ ++L+DA L++ +A P + + +G+ +
Sbjct: 4122 VALLAVLKAGGAYVPLDPDYPGERLRYMLEDAGVKLLLSHQAALPRLPEVAGIEVLDLDH 4181
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
L D+P A + + + +A ++YTSGSTG PKGV +++ AI
Sbjct: 4182 LPLN------DQPEQAPEV-NIHHEQLAYLIYTSGSTGKPKGVAVAHGAIAMHCQAIGER 4234
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRETTRDPQKL-VNIERLVLV 198
+ + +E+ + +++F D E W PL HG ++I ++ Q IE + V
Sbjct: 4235 YELT-AEDRELHFLSVSF-DGAHERWLTPLSHGARVVIRDQQLWSVQQTYDCLIEEGISV 4292
Query: 199 PTLLRSILMYLA-LGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L S L LA +K + +GE S+EL + + + + N YG
Sbjct: 4293 VALPPSYLRQLAEWAEQCGKAPGVKTYCFAGEAFSRELLQQVIRSLQPQ---WIINGYGP 4349
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + T + + + PIG + Y+LD +L+ GE+++ G L
Sbjct: 4350 TETVVTPTIWRVPAATADFDTAYAPIGDRVGARQGYVLDADLNLLPVGVAGELYLGGL-L 4408
Query: 318 AAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+ G A RF NP+ +P +RLYRTGD L G + Y GR D Q+K+RG R
Sbjct: 4409 ARGYLDRPGATAERFVPNPY--RPG-ERLYRTGDRVRLGADGQLEYLGRLDQQIKLRGFR 4465
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
+++ EVE AL GV + +V+ G ++G+V+ G S ++ +L+ L
Sbjct: 4466 IEIGEVEAALKACAGVGESLVVVKDSAAGK-RLVGYVS---GQALSESELKAQLKQRLPS 4521
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+M+P ++ +E +PLL NGK+DRQ L + ++
Sbjct: 4522 HMVPSHILALERLPLLPNGKLDRQSLPE--------------PQVEGGEYQAPRTEQEQL 4567
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGY 538
G +LG G +S + F+ LGG+S+ S+ +T+LR G+
Sbjct: 4568 LAELWGELLG---SGQISRDAQFFALGGDSIQSLSLVTRLRKAGW 4609
Score = 149 bits (362), Expect = 2e-34
Identities = 136/449 (30%), Positives = 215/449 (47%), Gaps = 33/449 (7%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ LLA K G AYVP++P +P R+ ++L+DA L++ A P + +G+ +
Sbjct: 2035 VVLLAVLKTGGAYVPLDPDYPGERLRYMLEDAGVKLLLSHQPALPRLPAVAGIEVFDLDH 2094
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
L D+P A + + + +A ++YTSGSTG PKGV +++ AI L Q
Sbjct: 2095 LQLN------DQPEQAPEV-DIHPEQLAYLIYTSGSTGKPKGVAVAHGAIA--LHCQAIG 2145
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLI-----LSRETTRDPQKLVNIER 194
Y + E D E W PL HG ++I S + T D I
Sbjct: 2146 ERYELTAEDRELHFLSVSFDGAHERWLTPLSHGARVVIRDQQLWSVQQTYDCLIAEGISV 2205
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ L P+ LR + + A P +K + +GE S+EL + + + + N
Sbjct: 2206 VALPPSYLRQLAEW-AEQCGKAP--GVKTYCFAGEAFSRELLQQVIRSLQPQ---WIING 2259
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE + T + + + PIG + Y+LD +L+ GE+++ G
Sbjct: 2260 YGPTETVVTPTLWRVPAATADFTTAYAPIGDRVGARQGYVLDADLNLLPVGVAGELYLGG 2319
Query: 315 ANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
LA GY+ A RF NP+ +P +RLYRTGD L G + Y GR D Q+K+R
Sbjct: 2320 L-LARGYLDRPAATAERFVPNPY--RPG-ERLYRTGDRVRLGADGQLEYLGRLDQQIKLR 2375
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R+++ EVE AL GV + +V+ G ++G+V+ G S ++ +L+
Sbjct: 2376 GFRIEIGEVEAALKACAGVGEALVVVKDSAAGK-RLVGYVS---GQGLSESELKMQLKQR 2431
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +M+P ++ +E +P L NGK+DRQ L
Sbjct: 2432 LPAHMVPSHILALERLPQLPNGKLDRQSL 2460
>UniRef50_A4KUB7 Cluster: TlmIV; n=3; root|Rep: TlmIV -
Streptoalloteichus hindustanus
Length = 2620
Score = 217 bits (529), Expect = 1e-54
Identities = 151/446 (33%), Positives = 222/446 (49%), Gaps = 25/446 (5%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
++ A+L KAG AYVP++P P R++ ++ DA P+L++ + G
Sbjct: 556 SVTAMLGILKAGGAYVPLDPDHPSTRLSAVIADAAPTLLVTTKEIQDRCPEYRGPVLLLD 615
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E +T +AD + P+ +D++A VL+TSGSTG PKGV + NR W
Sbjct: 616 SERDALSTEDTADLRL------PVRADNLAYVLHTSGSTGRPKGVLGLHRGAVNRAAWWE 669
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------I 192
+ +P+ E +C +TAL FVDSV E +GPL+ G LL+LS + DP +LV+ +
Sbjct: 670 KVYPFQPGE-VCAARTALGFVDSVWETFGPLIAGVPLLVLSPDEVADPVRLVDRLAAHRV 728
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
RLV VP+L + L+ L + L L+ WV SGE+LS LA F + G L
Sbjct: 729 TRLVGVPSL--ATLLLDELPDLDQRLPELRFWVLSGESLSGGLARRFHERL---PGRTLL 783
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YGS+E D T + S +PIGRP+ A+ + D L PGE+ V
Sbjct: 784 NLYGSSEASADATAAEIPHS---ATESRVPIGRPISGVAVQVRDSALRALPALAPGELHV 840
Query: 313 AGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
G LA GY P P R +RTGD G + Y GR D QV++R
Sbjct: 841 GGECLARGYHRRPAETAAVFLPAPDGPPGSRAFRTGDAARWRPDGQLDYLGRLDGQVQVR 900
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
GHRV+ EVE+AL+ P V V+ G+ ++G++ + LR
Sbjct: 901 GHRVEPGEVEQALSGHPDVRAAAVVARPDSTGSTALVGYLVA--DRNLDLAQVRDFLRQR 958
Query: 432 LTHYMMPQVI-EVESIPLLVNGKVDR 456
L Y++P ++ +V ++P+ +GKVDR
Sbjct: 959 LPGYLVPSLLTQVPALPMTPSGKVDR 984
Score = 179 bits (436), Expect = 2e-43
Identities = 161/567 (28%), Positives = 259/567 (45%), Gaps = 41/567 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDS-ADPSMFKESGVPFASF 78
++A L ++GAA+VP++P P R+TH+L AE + + + A+ F + A
Sbjct: 1623 VVAALGVLESGAAFVPVDPDLPAARLTHLLHRAEARIALTHLAVAEEVPFPDDLSVLAVD 1682
Query: 79 EELAQEATSHSADEPMDAETLAPLTS----DSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
++ A + S D + PL D +A V++TSGSTG PKGV + + N +
Sbjct: 1683 DDSALQDNSALQDNSALDASDEPLDRAQGMDDLAYVIFTSGSTGEPKGVMIDHRGAANTI 1742
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVN 191
+ F + + ++L+F ++ +++G L G +++ RDP +LV
Sbjct: 1743 RCVNQHFAVGPHDRVLA-VSSLSFDLAIYDLFGVLAAGGTVVLPRHSRRRDPAHWAELVA 1801
Query: 192 IERLVL---VPTLLRSILMYL-ALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
ER+ L VP L ++ Y AL P + LR L++ + SG+ + L +
Sbjct: 1802 TERITLWNSVPALAEVLVGYAEALAPQA--LRSLRVVMLSGDWIPVALPDRLRRLAPETH 1859
Query: 248 GYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP 307
L G+TE +Y + D + +IP G P+DN ++++LD LSP D
Sbjct: 1860 VRSLG---GATEGSIWSVWYPIGEVDPS--WRSIPYGMPMDNQSMHVLDRGLSPRPDWVA 1914
Query: 308 GEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRT 364
E+++ G +A GY A+ F +P + RLYRTGD L G + + GR
Sbjct: 1915 DELYIGGTGVALGYWRDPERTASSFLTHPDTGE----RLYRTGDIARYLPDGNLEFLGRE 1970
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHI 424
D QVKI G RV+L E+E L ++PGV V+ G RG + G+V +PG + +
Sbjct: 1971 DNQVKISGFRVELGEIESTLERLPGVRTAAVVAVGDPRGEKRLAGYVAREPGEQVDPTAL 2030
Query: 425 EGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXX 483
+L L +++P + V + +PL NGKVDR L E + D D
Sbjct: 2031 RRRLAELLPSHLVPPTLHVLDQLPLTNNGKVDRAELRSRAE--KRPAVRQEPRDRDPGRA 2088
Query: 484 XXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEI 542
+ + GF+ LGG SL +I +T + RDRG + +
Sbjct: 2089 HALVPEIVALWREVLEV-------DEIDPDDGFFALGGTSLQAIRLLTLIQRDRGIRIPL 2141
Query: 543 SDFLGAST---LGEVLSKMSTDPNGGA 566
+ L A T L E ++ + P G A
Sbjct: 2142 ARLLDAPTVLALAEAIADAESGPAGPA 2168
>UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular
organisms|Rep: CDA peptide synthetase I - Streptomyces
coelicolor
Length = 7463
Score = 216 bits (528), Expect = 2e-54
Identities = 152/459 (33%), Positives = 227/459 (49%), Gaps = 26/459 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSAD--------PSMFKES 71
++ALLA K+GAAYVP++P +P R+ H L D+ P+ ++ D + P + ++
Sbjct: 1733 VVALLAVVKSGAAYVPLDPGYPADRLAHALSDSAPAALLTDRATAGRLPAHEVPRIVLDA 1792
Query: 72 GVPFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAIC 131
P A +H A + E + PL A V+YTSGSTG PKGV + + +
Sbjct: 1793 PAPADGGTTGGDPADAHPATDLAQGERVRPLDPRDTAYVIYTSGSTGRPKGVAVPHGNVV 1852
Query: 132 NRLWWQFRTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL 189
RL+ T P+ +E VW + F SV E+WGPLLHG L+++ + TRDP
Sbjct: 1853 -RLF--SATAPWFGFDEHDVWTLFHSYAFDFSVWELWGPLLHGGRLVVVPHDVTRDPAAF 1909
Query: 190 VNI--ERLVLVPTLLRSILMYLALGPASRPLR-RLKLWVCSGETLSKELASEFFKYFGNE 246
+ + V V S LA P L+ V GE L +++++ E
Sbjct: 1910 LALLARERVTVLNQTPSAFHQLAAADRENPTELALRTVVFGGEALDLSRLADWYERHA-E 1968
Query: 247 DGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSE 306
D L N YG TE V+++ L+ + + IG + + +Y+LD+ L PT
Sbjct: 1969 DAPALVNMYGITETTVHVSHFALDRATAAASSAST-IGVNIPDLRVYVLDDRLRPTAPGV 2027
Query: 307 PGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQ--PEFQRLYRTGDFGTL-VKGAVLYA 361
GE++VAGA LA GY+G A+RF +P+A R+YRTGD G + Y
Sbjct: 2028 TGEMYVAGAGLARGYLGRPALTADRFPADPYAALFGERGTRMYRTGDLARRRTDGGLDYL 2087
Query: 362 GRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA 421
GR D QVKIRG R++ E+E LA P VD V+ +G+P ++ +V T GA A
Sbjct: 2088 GRADQQVKIRGFRIEPGEIEAVLAAHPAVDDVAVVAREDVQGDPRLVAYVVTGSGATARA 2147
Query: 422 QHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
H L +M+P + ++ +PL NGK+D + L
Sbjct: 2148 LH--DHAAGHLPDHMLPSAFVTLDVLPLTPNGKLDTKAL 2184
Score = 202 bits (492), Expect = 4e-50
Identities = 155/415 (37%), Positives = 210/415 (50%), Gaps = 32/415 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYD-DSADPSMFKESGVPFASF 78
++ALLA K+GAAYVP++P +P RI HIL+DA LV+ D+A+ G P
Sbjct: 534 VVALLAVLKSGAAYVPVDPGYPADRIAHILRDAGAMLVLTTRDTAE--RLPGDGTPRLLL 591
Query: 79 EELAQEATSHSADEPMDAETL--APLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+E A T+ +A P TL A A V+YTSGSTG PKGV +S+ AI NRL W
Sbjct: 592 DEPAAAGTT-AAGAPAPPGTLPRALPAPGHPAYVIYTSGSTGRPKGVVISHRAIVNRLAW 650
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER-- 194
T+ S+ + + KT F SV E + PL+ G L++ DP L R
Sbjct: 651 MQDTYGLEPSDRV-LQKTPSGFDVSVWEFFWPLVQGATLVVARPGGHTDPAYLAGTVRRE 709
Query: 195 ----LVLVPTLLRSIL---MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
L VP++L L ALG A+ P+RR+ CSGE L EL + F
Sbjct: 710 GVTTLHFVPSMLDVFLREPAAAALGGAT-PVRRV---FCSGEALPAELRARFRAV----S 761
Query: 248 GYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP 307
L N YG TE DVTY+ D D +PIGRP+ N +Y+LD L P P
Sbjct: 762 DVPLHNLYGPTEAAVDVTYWPC-AEDTGD--GPVPIGRPVWNTRMYVLDAALRPVPAGVP 818
Query: 308 GEVWVAGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRT 364
GE+++AG LA GY+G A RF +PH R+YRTGD G++ Y GR
Sbjct: 819 GELYIAGVQLARGYLGRPALSAERFTADPHGAPG--SRMYRTGDLARWNHDGSLDYLGRA 876
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART 419
D QVK+RG R++L E+E AL + P + + V+ G+ ++ + A T
Sbjct: 877 DHQVKLRGFRIELGEIEAALVRQPEIAQAAVVLREDRPGDQRLVAYTVPARDADT 931
Score = 194 bits (472), Expect = 1e-47
Identities = 164/562 (29%), Positives = 256/562 (45%), Gaps = 40/562 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++ LA +KAGAAY+P++P+ P RITH++ DA P+L++ SA + ++G P +
Sbjct: 2822 VLSALAAFKAGAAYLPVDPAHPAERITHLVSDAAPTLIV-TTSALAASLPDTGTPVLLLD 2880
Query: 80 --ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E A + + DA+ PL + A ++YTSG+TG PKGV ++++ + L
Sbjct: 2881 TPETAATLAALPGHDVTDADRPVPLRPEHPAYMIYTSGTTGRPKGVVVTHTGLPGLLDIF 2940
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
R I + + +F S E+ LL G L++ ETT P+ R
Sbjct: 2941 TRDCAAGPGSRI-LQHLSPSFDASFWELAMGLLTGATLVVAPPETTPGPELAELATRHAA 2999
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L + ++ L L P S P L L V E + EL + G + N YG
Sbjct: 3000 THLSLTTSVLGL-LPPDSLP-DGLTL-VVGAEAIPPELVERW------SPGRTMLNSYGP 3050
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T S L PIG P+ N A+Y+LD L P PGE++ AGA+L
Sbjct: 3051 TETTVCSTM-----SGPLSGPAVPPIGSPVANSAVYVLDAALRPVPPGVPGELYAAGAHL 3105
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY A RF NP +P RLYRTGD G + Y GR D QVKIRG R
Sbjct: 3106 ARGYHDRRALTAERFVANPFG-EPG-SRLYRTGDLVRWRPDGQLEYLGRADTQVKIRGLR 3163
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++ E+E + + P + + V+ G+ ++ +V +PGA + LR L
Sbjct: 3164 IEPTEIEAVITERPHLARAAVIVREDRPGDRRLVAYVVPEPGATVDTAELRAALRETLPD 3223
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+M+P + ++++PL +NGK+DR+ L + + A
Sbjct: 3224 HMIPTAFVVLDALPLTLNGKLDRKALPAPDYSARTSGRA-------------ARDPRERL 3270
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
G +LG G + GF++LGG+S+ SI + + R G + + D T
Sbjct: 3271 LTALFGEILGVEPAG---VDDGFFDLGGDSILSIQLVARARAAGLVLSVRDVFEHQTPAL 3327
Query: 554 VLSKMSTDPNGGADSKEATFTA 575
+ + P G ++++ A
Sbjct: 3328 LARSAAAAPAGDRTARDSDVPA 3349
Score = 187 bits (455), Expect = 1e-45
Identities = 136/444 (30%), Positives = 213/444 (47%), Gaps = 42/444 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++LA K GAAY+P++P +P RIT++L DA P+L + +P VP +
Sbjct: 4341 VISMLAVLKTGAAYLPIDPDYPAERITYMLDDARPALTL----TEP-------VPVERY- 4388
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
T HS D E +P ++ A ++YTSGSTG PKGV + + A+ L
Sbjct: 4389 ------TGHSVTAVTDEERRSPWSARHAAYMIYTSGSTGRPKGVVIEHHALATYLHRARN 4442
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T Y+ + V + L F ++ +W PL G + + S E + L+ P
Sbjct: 4443 T--YTAMTGVTVLHSPLAFDLTITALWTPLTSGGTVHLTSLEESDTQPSLIKA-----TP 4495
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ L + L + P L + GE L + + G ++ N YG TE
Sbjct: 4496 SHLP---LLTTLPETASPSHTL---ILGGEALHTD---HLVTWRTQHPGVQIINAYGPTE 4546
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
++T + + G D D +PIGRP N +Y+LD L P GE+++AG LA
Sbjct: 4547 STVNITDHHV-GEDTPD--GPVPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLAR 4603
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHRVD 376
GY+G A RF NPH++ P R+YRTGD G + Y GR D Q+K+RGHR++
Sbjct: 4604 GYLGRPALTAERFTANPHSSTPG-ARMYRTGDLAHWNHHGHLTYDGRADHQIKLRGHRIE 4662
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
E+E L G+ + V G+ ++ ++ + + L SAL YM
Sbjct: 4663 PGEIEATLTAQTGITQATVQLREDQPGDQRLVAYLVVNDSTEYDEKTVRDALTSALPDYM 4722
Query: 437 MPQ-VIEVESIPLLVNGKVDRQGL 459
+P ++ ++++PL NGK+DR L
Sbjct: 4723 VPSALVTLDALPLTPNGKLDRTAL 4746
Score = 180 bits (439), Expect = 1e-43
Identities = 134/445 (30%), Positives = 211/445 (47%), Gaps = 44/445 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++LA K GAAY+P++P +P RIT++L DA+P+L + + +P AS++
Sbjct: 5381 VISMLAVLKTGAAYLPIDPDYPAERITYMLDDAQPALTL-----------TAPIPPASYD 5429
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
S E D E +P ++ A ++YTSGSTG PKGV + + A+ L
Sbjct: 5430 -------SRPTSEITDVERRSPWSARHAAYMIYTSGSTGRPKGVVIEHHALATYLHRARN 5482
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T Y+ + V + L F ++ +W PL G + + S E L+ P
Sbjct: 5483 T--YTAMTGVTVLHSPLAFDLTITALWTPLTAGGTVHLTSLEEAEVQPSLIKA-----TP 5535
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ L + L + P L + GE L + + G ++ N YG TE
Sbjct: 5536 SHLP---LLTTLPETASPSHTL---ILGGEALHTD---HLATWRTQHPGAQIINAYGPTE 5586
Query: 260 VMGDVT-YYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
++T ++V E + +PIGRP N +Y+LD L P GE+++AG LA
Sbjct: 5587 STVNITDHHVSEDTPD----GPVPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLA 5642
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
GY+G A RF NPH++ P R+YRTGD G + Y GR D Q+K+RGHR+
Sbjct: 5643 RGYLGRPALTAERFTANPHSSTPG-ARMYRTGDLAHWNHDGHLTYDGRADHQIKLRGHRI 5701
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+ E+E L G+ + V G+ ++ ++ + L SAL Y
Sbjct: 5702 EPGEIETTLTAQTGITQTTVQLREDTPGDQRLVAYLVVNDSTEYDEPTLRDALASALPDY 5761
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGL 459
M P + ++++PL NGK+DR L
Sbjct: 5762 MRPSAYVTLDALPLTPNGKLDRTAL 5786
Score = 154 bits (374), Expect = 8e-36
Identities = 154/582 (26%), Positives = 254/582 (43%), Gaps = 57/582 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA KAG AYVP+ ++P R+ H++ D +L++ D A+ + + G +
Sbjct: 6419 VVATLAIAKAGGAYVPLHDTYPLDRMRHVVADTAATLIL-TDRAEAARAGQLGARVMVVD 6477
Query: 80 ELAQEATSHSADEPMDAETL------------AP---LTSDSIAIVLYTSGSTGIPKGVR 124
E + AD T AP L +A V+YTSGSTG+PKGV
Sbjct: 6478 EFGAAPSGSEADAAPGTGTGTGTGSRSGYVDDAPEVGLRPQDLAYVMYTSGSTGVPKGVA 6537
Query: 125 LSYSAICNRLWWQFRTFPYSDSEEICVWKTALTFVDSVC-EIWGPLLHGRALLILSRETT 183
+++ + + + R + V A D C E+W PL+ G ++++
Sbjct: 6538 VTHRGVVDLV----RDHCWRPGVHERVLLHAPHAFDVSCYEMWVPLVSG-GTVVVAPPGH 6592
Query: 184 RDPQKLVNIERLVLVPTL-LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKY 242
DP + ++ + + L + + A ++ + G+ +S + +
Sbjct: 6593 LDPAAITDLITAHDITAIHLTAGFFRVVAEEAPECFAGVREVLTGGDVVSPAAVA---RV 6649
Query: 243 FGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPT 302
+ L + YG TE VT + E + + ++P+GR N Y+LD L P
Sbjct: 6650 LAHHPRIVLRHLYGPTETTLCVTQH--EVTAPYEARGSLPVGRATGNTRAYVLDRYLQPV 6707
Query: 303 RDSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVL 359
PGE++++G+ LA GY+ RF +P+ E R+YRTGD G +
Sbjct: 6708 PAGVPGELFISGSGLARGYLDRPDLTCERFVADPYGGSGE--RMYRTGDLVRYNAAGELE 6765
Query: 360 YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG--A 417
Y R D QVKIRG RV+L E+E LA P + + V+ G+ ++G+V G
Sbjct: 6766 YLARADDQVKIRGFRVELGEIEAVLATRPELAQAAVVVREDRPGDRRLVGYVVAAAGRDG 6825
Query: 418 RTSAQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAV 476
+ R AL YM+P + + ++PL NGK+DR+ L A
Sbjct: 6826 EVDPDALRAFSRQALPDYMVPSAFVVLGTLPLTANGKLDRKAL--------------PAP 6871
Query: 477 DIDCSXXXXXXXXXXXXXXXTVGA-VLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
D + T+ A VLG +A G + GF++LGG+S+ SI +++ R
Sbjct: 6872 DYGAASTGRAARTPAEELLCTLFAQVLGLSAVG---VDDGFFDLGGDSILSIQLVSRARA 6928
Query: 536 RGYYVEISDFLGASTLGEVLSKMSTDPNGGADSKEATFTAVP 577
G + + D + + + + TD + A EA AVP
Sbjct: 6929 AGLALAVRDVFEHQSTARLAAAL-TDRDDAASVPEA--EAVP 6967
>UniRef50_Q4IYK4 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=4; Gammaproteobacteria|Rep: Non-ribosomal
peptide synthase:Amino acid adenylation - Azotobacter
vinelandii AvOP
Length = 3933
Score = 216 bits (528), Expect = 2e-54
Identities = 174/540 (32%), Positives = 264/540 (48%), Gaps = 52/540 (9%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ LLA KAG AYVP++P +P+ R+ ++++D+ L++ + GV
Sbjct: 1625 FEMVVGLLAILKAGGAYVPLDPEYPRERLAYMIEDSGIGLLLTQRHLQDRLPSADGVQSL 1684
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
E ++ + P A AP ++A V+YTSGSTG PKG +++A+ NRL W
Sbjct: 1685 FLEPGDDWLENYPPENP--ANRTAP---QNLAYVIYTSGSTGRPKGAGNTHTALINRLHW 1739
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER- 194
+ + D+ + + KT +F SV E++ PLL+G L I RDP++L++ IER
Sbjct: 1740 MQKAYQL-DTTDTVLQKTPFSFDVSVWELFWPLLNGARLAIARPGEHRDPERLIDTIERH 1798
Query: 195 ----LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
L VP++L++ + + R +RRL VCSGE L ELA K
Sbjct: 1799 GVTTLHFVPSMLQAFISVEHI-EGCRSIRRL---VCSGEALPAELAR---KTLERMPAVG 1851
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE DVT++ + D +PIG+P+DN ++L+E L P GE+
Sbjct: 1852 LFNLYGPTEAAIDVTHWTCDHVDP----EGVPIGQPIDNLKTHILEESLHPVAPRCCGEL 1907
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPE-FQRLYRTGDFGTLVKGAVL-YAGRTDA 366
++ G LA GY G A RF +P T + RLYRTGD G V+ Y GR D
Sbjct: 1908 YLGGVGLARGYHNRPGLTAERFIPDPFDTSEQGGGRLYRTGDLARYRAGGVIEYLGRIDH 1967
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVKIRG R++L E+E L Q V + VV+ G ++ ++ A +G
Sbjct: 1968 QVKIRGFRIELGEIEARLRQHGAVREAVVIDVE-GAGGRQLAAYLVPDDPAMLDGDERQG 2026
Query: 427 --------KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVD 477
LR+AL YM+P ++ + +PL NGK+DR+ L + N + A VA
Sbjct: 2027 ALRGELKDHLRAALPDYMVPAHLVFLARLPLTPNGKLDRKALPR--PNASLLQRAYVA-- 2082
Query: 478 IDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRG 537
+ A + + R + L F+ELGG+S+ SI +++ R G
Sbjct: 2083 ---------PASELEQRIAAIWAEVLKVER--VGLTDNFFELGGDSIVSIQVVSRARQAG 2131
Score = 161 bits (390), Expect = 9e-38
Identities = 137/454 (30%), Positives = 213/454 (46%), Gaps = 43/454 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAGAAY+P+EP PQ R+ +L D++ LV+ S + + GV +
Sbjct: 578 LVGILGILKAGAAYLPLEPDQPQERLAFMLADSDVRLVLGRSSWEGLL--PDGVRMICLD 635
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + A ++ ++A V+YTSG+TG+PKGV + + A+ N + R
Sbjct: 636 EPLPPVSG-------SAGLHVRVSPGNLAYVIYTSGTTGMPKGVAVPHGALANYVEGISR 688
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
P + + T + ++G L G+ L +L +ET D + ++
Sbjct: 689 RLPLEAISSMAMVSTPAADLGHTV-LFGALCAGKTLHLLDKETVLDAEAFAAHMDAHGVD 747
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L +VP+ L ++L + G ++ P R L V GE L + K+ N
Sbjct: 748 ALKIVPSHLDAML---SAGRSALPRRCL---VLGGEACPPALLARIVALAPE---LKVLN 798
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T VL G +L P + G PL+N + LD L P GE+ ++
Sbjct: 799 HYGPTET----TVGVLIG--ELKGLPVL--GSPLENVGVRRLDACLQPAPGPAKGELHIS 850
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
GA LA GY+G A RF +P T R+YRTGD+ G +L+AGR D QVKI
Sbjct: 851 GAGLARGYLGRPALTAERFVPDPSGTPGG--RMYRTGDWVRRNADGGLLFAGRMDGQVKI 908
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK----PGARTSAQHIEG 426
RG+RV+L E+E L +PGV ++ G + + V T + I
Sbjct: 909 RGYRVELAEIESRLRALPGVGNALLRVIGEEHARQLVAYLVPTAVPDGQAGQAFLDEIRT 968
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L+ L +M+P ++ +E +P+ NGKVD + L
Sbjct: 969 VLKRVLPEHMVPTHLLVLEHLPVTANGKVDLKAL 1002
Score = 148 bits (359), Expect = 5e-34
Identities = 146/560 (26%), Positives = 239/560 (42%), Gaps = 43/560 (7%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ LLA KAG AYVP++P +P R+ +++ D+ L++ + G
Sbjct: 3139 FEMVVGLLAILKAGGAYVPLDPEYPGERLAYMIGDSGVGLLLTQRHLQDRLPSADGAQSL 3198
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
E + + P A P ++A V+YTSGSTG PKG + + N L W
Sbjct: 3199 FLEPDDDWLEGYGEENP--ANRTMP---QNLAYVIYTSGSTGQPKGAAVRIGSFVNLLHW 3253
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+R +++ + ++ +F + ++G L G L I D + + +
Sbjct: 3254 -YRAACELTADDRVLLLSSYSFDLTQKNLYGVLCAGGQLHIAPAGYDPDSHRRQIGKHRL 3312
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V S L G + L LK + GE + +E+ + N YG
Sbjct: 3313 SVLNCAPSAFYPLLQGDRAE-LASLKHVLLGGEAIQPGELAEWLD-SPQAANVSIHNTYG 3370
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE V GS L T+PIGRPL + Y+LD P + GE+ V G
Sbjct: 3371 PTECTDVVIARATPGSAVPGL-STLPIGRPLPGVSAYVLDGSAGPVALGQAGELHVGGDC 3429
Query: 317 LAAGYVGGGG--ANRFCDNP-HATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
+ GY G A+RF +P ++ RLYRTGD G + Y GR D QVKIRG
Sbjct: 3430 VGEGYWHRPGLTADRFVPDPFDDSEQGGGRLYRTGDLARYRTDGVIEYLGRIDHQVKIRG 3489
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQH----IEGKL 428
R++L E+E L Q V + VV+ G+ ++ ++ A + G+L
Sbjct: 3490 FRIELGEIEARLQQHGAVREAVVIDID-GPGSKQLAAYLVPDAPAMLDGDERQTGLRGEL 3548
Query: 429 R----SALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXX 483
+ + L YM+P ++ +E +PL NGK+DR+ L + D S
Sbjct: 3549 KAHLGAVLPDYMVPVHLVFLERLPLTPNGKLDRKALPRP----------------DVSLL 3592
Query: 484 XXXXXXXXXXXXXTVGAVLGRAAR-GTLSLRSGFYELGGNSLNSIYTITK---LRDRGYY 539
+ A+ + + L F+ELGG+S+ ++ ++K L++ G+
Sbjct: 3593 QRAYVAPASELEQRIAAIWAEVLKVERVGLTDNFFELGGDSIIAVQLVSKLKALKEYGFD 3652
Query: 540 VEISDFLGASTLGEVLSKMS 559
+ D + T+ ++L+ S
Sbjct: 3653 STLQDLMQKPTISDLLNNNS 3672
>UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2;
Comamonadaceae|Rep: Amino acid adenylation domain -
Delftia acidovorans SPH-1
Length = 1789
Score = 215 bits (526), Expect = 3e-54
Identities = 176/557 (31%), Positives = 250/557 (44%), Gaps = 38/557 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP++P P RI ++L+D+ SLV+ +
Sbjct: 1229 VVGLLAIMKAGAAYVPIDPEHPADRIAYMLEDSGVSLVLVQPQVRDRLPANCSAQLVDVP 1288
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA A P A L DS+ V+YTSGSTG PKG + ++CNRL W
Sbjct: 1289 GLASRLQDMPAHNPAVA-----LHGDSLVYVIYTSGSTGRPKGAANRHRSLCNRLAWGQV 1343
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P + + + KT F S E + PL G L + + RDP++L + V
Sbjct: 1344 HQPLGPGDTV-LQKTPFGFDISFWEFFWPLTTGARLALAAPGDHRDPRRLAELIARHQVS 1402
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T+ + S+L PA+ + L+ +CSGE LS EL + + F G +L N YG
Sbjct: 1403 TIHFVPSMLQAFMAHPAAATCQGLQRIICSGEALSAELQAAVLQAF---PGTRLLNLYGP 1459
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE +VT++ L ++PIGRP+ ++LD L+ GE+++ G L
Sbjct: 1460 TEAAIEVTWWDCRDEGAL----SVPIGRPVAGLRTHVLDAALNEVPRGVAGELYLGGVGL 1515
Query: 318 AAGY--VGGGGANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHR 374
A GY G A RF +P + E RLYRTGD G + Y GR D QVKIRG R
Sbjct: 1516 ARGYWRRPGLSAERFVADPASRTGE--RLYRTGDLVRWRGDGQIDYLGRVDHQVKIRGFR 1573
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L EVE L P V + VV+ G + FV+ + G + L +AL
Sbjct: 1574 IELAEVEAQLLAHPAVREAVVVARQAADG-ARLAAFVSVQQGQTLDMAALRSALAAALPD 1632
Query: 435 YMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P I V +++PL NGKVDR+ L DA ++
Sbjct: 1633 YMLPSSITVLDALPLNANGKVDRKAL----------PDAPALPALERQAYEPPEGGVAAT 1682
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
VLG G F++LGG+SL I L R G + + D T+
Sbjct: 1683 IAALWAQVLGVERIGA---SDNFFDLGGHSLQLIRVHGLLESRLGRELSLVDLFKHPTVS 1739
Query: 553 EVLSKM--STDPNGGAD 567
+ ++ D GG D
Sbjct: 1740 ALARRIEQGADGEGGGD 1756
Score = 48.4 bits (110), Expect = 7e-04
Identities = 36/121 (29%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 291 AIYLLD-EELSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGD 349
A+ ++D L GE+W G +++ GY G + HA + R RTGD
Sbjct: 389 AVAIVDPHSLQVLEPGHVGEIWAHGPSISQGYWGKPQQTQQAFVEHAGR----RWLRTGD 444
Query: 350 FGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERAL-AQVPGVDKCVVLCYGLDRGNPEIL 408
G + G V AGR + +RGH + ++ER + A+V V K V + +D E +
Sbjct: 445 LGFVHGGQVHVAGRIKDLIIVRGHNLYPQDIERVVEAEVEAVRKGRVAAFAVDIDGREGI 504
Query: 409 G 409
G
Sbjct: 505 G 505
Score = 36.7 bits (81), Expect = 2.4
Identities = 47/165 (28%), Positives = 67/165 (40%), Gaps = 13/165 (7%)
Query: 22 ALLATWKAGAAYVPMEPSFPQGRITH------ILKDAEPSLVIYDDSADPSMFKESGVPF 75
++LA + AG VP+ P R+ H I+ DA+ + VI S M G
Sbjct: 89 SMLACFYAGVIAVPVPP-LESLRVQHLERLLGIVGDADAACVI---STAEVMQALPGAD- 143
Query: 76 ASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSY-SAICNRL 134
A F +A A DA +D IA + YTSGST PKGV +S+ + I N
Sbjct: 144 ARFAGIAAVAADQVDLADADAWRPHAPAADDIAFLQYTSGSTSAPKGVMVSHGNLIANEA 203
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILS 179
Q R + W + + + PL G L++ S
Sbjct: 204 AIQQR-MDIGAGDRFMSWAPLYHDMGLIGGLLQPLYSGLPLVLTS 247
>UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8;
Bacteria|Rep: Non-ribosomal peptide synthase - Myxococcus
xanthus (strain DK 1622)
Length = 3906
Score = 215 bits (525), Expect = 4e-54
Identities = 171/558 (30%), Positives = 274/558 (49%), Gaps = 45/558 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++LL KAG AYVP++PS+PQ R+ +L+DA +++ +F E+ V F
Sbjct: 1223 VVSLLGVLKAGGAYVPLDPSYPQERLDFMLRDAAVRVLLTQQRL-AKVFTEAAVTRV-FV 1280
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + A A+ P + + S+S+A V+YTSGSTG PKG +++ + NRL W
Sbjct: 1281 DADERAPFQHAESPRRSASW----SESLAYVIYTSGSTGRPKGAMNTHAGVRNRLLWMQS 1336
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIERLV 196
+ S + + + KT L+F SV E + PL+ G L++ +DP ++L+ E +
Sbjct: 1337 EYGLSADDRV-LQKTPLSFDVSVWEFFWPLMTGARLVLARPGGHQDPAYLKQLIQDEAIT 1395
Query: 197 ---LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VP+++++ L A+ + LRR+ SGE LS EL F +L N
Sbjct: 1396 TAHFVPSMMQAFLAESAVEQCAS-LRRV---FSSGEALSPELRDHFVARLPET---RLYN 1448
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DV+ + S T+PIG+P+ N A+Y+LD L+P PGE+++
Sbjct: 1449 LYGPTEAAVDVSAWDCHRSLPSR---TVPIGQPVANTALYVLDTRLAPLPVGVPGELYIG 1505
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKI 370
G + GY+G A RF + A + E R+YRTGD L G++ Y GR D QVK+
Sbjct: 1506 GVQVGRGYLGRPDLTAERFVPDGFARE-EGMRMYRTGDRARVLPDGSLEYLGRLDHQVKV 1564
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RGHR++L E+E L Q P V + VVL + +++ F++ + A T A + L
Sbjct: 1565 RGHRIELGEIEATLEQHPAVQQAVVLARTAVGDDVQLVAFISHRGHAPTPAT-LRDFLAE 1623
Query: 431 ALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L +M+P I + +PL +GK DR L +V ++ S
Sbjct: 1624 RLPGFMVPSHIGILAELPLGPSGKRDRLAL--------------ASVQVEASDNGLEWMA 1669
Query: 490 XXXXXXXTVGAVLGRA-ARGTLSLRSGFYELGGNSLNSIYTITKLRD-RGYYVEISDFLG 547
TV + R + F++LGG+SL + + +LR G V + F
Sbjct: 1670 PRTPTELTVARIWSDVLKRERIGANDDFFQLGGHSLLATRVVARLRAILGVEVPLHTFFA 1729
Query: 548 ASTLGEVLSKMSTDPNGG 565
A T+ + ++ + +GG
Sbjct: 1730 APTVAALAERLQSCRSGG 1747
Score = 180 bits (437), Expect = 2e-43
Identities = 160/572 (27%), Positives = 255/572 (44%), Gaps = 37/572 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAE-PSLVIYDDSADPSMFKESGVPFASF 78
++ALL KAG AY+P++P+FP R+ +++DA +LV AD +P S
Sbjct: 2284 VVALLGILKAGGAYLPLDPTFPPERLGFLVQDARMAALVTRSGLADD--LPVQWIPVVSL 2341
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+E A + P ++ A VLYTSGSTG PKGV + A+ + +
Sbjct: 2342 DEDAAALAARPTANPTPV-----CNAEHEAYVLYTSGSTGKPKGVAVPQRAVVRLV--RN 2394
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVL 197
+ + +E + L F S E+WG LL+G A L + TT ++L + I R +
Sbjct: 2395 THYVHLGPDETLLQFAPLAFDASTFEVWGALLNG-ARLAIHPPTTPSLEELGSFIARQGV 2453
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L + L + + A L ++ + G+ LS + + G ++ N YG
Sbjct: 2454 TTVWLTAGLFHQVVDHALESLASVRQLLAGGDVLSPAHVRRVVERY---PGCRVINGYGP 2510
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + + + L +PIGRP+ N I++L+ L P PGE+ G L
Sbjct: 2511 TENTTFTCCHTVSPDEPL--VNAVPIGRPISNTRIHVLNAALEPVPVGAPGELCAGGDGL 2568
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF +P + P RLYRTGD L G V + GR D QVK+RG R
Sbjct: 2569 ALGYLNDPALTAQRFIPDPFSPVPG-ARLYRTGDRCHVLPDGRVEFLGRVDEQVKLRGFR 2627
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR-TSAQHIEGKLRSALT 433
++ E+E ALA P V + V+ G +++ ++ +P A+ + L++ L
Sbjct: 2628 IEPGEIEAALALHPTVHEARVMAREDGPGEKQLVAYLVARPSRELPPAEDLRRYLQARLP 2687
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
+M+P + + + PL NGKVDR+ L + VA
Sbjct: 2688 VFMVPSAFVTLAAFPLTANGKVDRRALPAPTGPERAASERYVA----------PRTADEE 2737
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLG 552
VLG T SL F++ GG+S+ +I + + +RG + ++ L TL
Sbjct: 2738 VLAGVWSEVLG---VDTPSLHDSFFDAGGDSIRAIQFVARAAERGLKLSVAMLLENQTLQ 2794
Query: 553 EVLSKM-STDPNGGADSKEATFTAVPMRDEHK 583
V + + + G + A F V + D +
Sbjct: 2795 AVAEALRAGNTTEGPTAPTAPFDLVRLVDRER 2826
Score = 180 bits (437), Expect = 2e-43
Identities = 148/456 (32%), Positives = 220/456 (48%), Gaps = 41/456 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+L KAG AYVP++P+ P+ R+ +L++A P+ V+ P++ VP
Sbjct: 3353 VVAMLGVLKAGGAYVPLDPAHPKARLEAVLQEAHPAAVVTRRELAPNL-PVREVPTL--- 3408
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L ++A H P +AP ++A VLYTSGSTG PKGV + + + N F
Sbjct: 3409 -LVEDAPEHPL--PPLTRGVAP---RNLAYVLYTSGSTGRPKGVMVDHGNLVN----HFV 3458
Query: 140 TFPYS-DSEEICVW--KTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
T ++ W T TF S E+ L G L+I E IE
Sbjct: 3459 TLDERIEARPAGTWLAVTPYTFDISGVELVWTLTRGFHLVIHPEERHARRSVAEQIEHHA 3518
Query: 197 LVP---TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ T R+ L+ + G A R L RL++ V GE L+ LA+E +L N
Sbjct: 3519 ITHLQCTPSRASLLLQSPGMA-RALARLRVLVLGGEALTPALAAELRTRLTG----RLLN 3573
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T + +E S PT+PIGRP+ N +Y++D +P GE+ +
Sbjct: 3574 IYGPTETTIWSTTHAVEASG-----PTVPIGRPVSNTEVYIVDAHGTPVPMGAAGELLIG 3628
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKI 370
G ++ GY+ A RF NP +++P RLYRTGD G VL + GR D QVKI
Sbjct: 3629 GEGVSRGYLHRPELTAERFIPNPFSSRPG-ARLYRTGDACRYQPGGVLEFLGRIDQQVKI 3687
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFV------TTKPGARTSAQHI 424
RG+R++L EVE L + P + + V+ D ++ ++ T + H+
Sbjct: 3688 RGYRIELGEVEAVLREHPALREAAVVARTQDDDAARLVAYLVPSQRDTPLENLQALVAHV 3747
Query: 425 EGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
LR L YM+P + +E++PL +GKVDRQ L
Sbjct: 3748 RAFLRERLPEYMVPSAFVPLEALPLNASGKVDRQAL 3783
Score = 43.6 bits (98), Expect = 0.021
Identities = 47/196 (23%), Positives = 83/196 (42%), Gaps = 12/196 (6%)
Query: 270 EGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTR-DSEPGEVWVAGANLAAGYVGGGGAN 328
EG+ Q D + G L ++ ++D + + D E GE+W++G ++A GY G
Sbjct: 371 EGTGQ-DTVTLVSSGTQLPTQSLVVVDPQARTLQADGEVGEIWMSGPSVAQGYWGRPEET 429
Query: 329 RFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQV- 387
+ E L RTGD G L G + GR + IRG ++E+ Q
Sbjct: 430 ERVFQARLARGEGPFL-RTGDLGFLRDGQLFVTGRAKDLIIIRGRNHYPQDLEQTTEQSH 488
Query: 388 PGVDKCVVLCYGLDRGNPEILGFVTTKPGAR--TSAQHIEGKLRSALT-HYMM----PQV 440
P + + +D E L V + AR S + ++ A+ H+ + +
Sbjct: 489 PAIRPGCSAAFSVDVDGEEHLA-VAFEVSARQEVSPDDVATSVQQAIAEHHQLGVHAVLL 547
Query: 441 IEVESIPLLVNGKVDR 456
++ ++P +GK+ R
Sbjct: 548 LKAGALPKTSSGKIQR 563
Score = 34.7 bits (76), Expect = 9.7
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 102 LTSDSIAIVLYTSGSTGIPKGVRLSY 127
+T ++A + YTSGSTG PKGV L++
Sbjct: 170 VTGQTLAFLQYTSGSTGTPKGVMLTH 195
>UniRef50_UPI000038CB2F Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 918
Score = 215 bits (524), Expect = 5e-54
Identities = 139/446 (31%), Positives = 228/446 (51%), Gaps = 19/446 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAG AYVP++P++P R+ IL+D + +++ + ++ +
Sbjct: 106 IVGLLGILKAGGAYVPLDPAYPSERLAFILEDTQTPVLLTQEKLLNNLPPHQA-QVVCLD 164
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
Q +S + P++ D++ V+YTSGSTG PKGV + + ICN+L+W+ +
Sbjct: 165 SNWQGNIQNSQENPVNQTA-----GDNLIYVIYTSGSTGQPKGVMIPHRGICNQLYWRQK 219
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
TF + ++++ + + +F SV +I+ PL G L + +D LV + E+ +
Sbjct: 220 TFRLTQADKVLL-TISFSFDPSVWQIFWPLCFGGQLTVARPGGHQDTAYLVKVITEQQIT 278
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V L+ SIL L L+ C GE L EL FF G ++ L N YG
Sbjct: 279 VLALVPSILRILLEEKGIENCPFLRHITCGGEALPGELIERFFAKLGLDN--VLYNCYGP 336
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE D T++ + + PIGRP+ N I++LD+ L P E GE+ + G L
Sbjct: 337 TEASIDTTFWTCQRGTNSTI---APIGRPITNAEIHILDDNLQPVPAGESGELHIGGIGL 393
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ ++F NP +++P RLY+TGD L G + + GR D QVKIRG R
Sbjct: 394 ARGYLNRPELTIDKFIFNPFSSEPG-ARLYKTGDLARYLSDGNIEFLGRIDDQVKIRGFR 452
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L Q P + + +V+ G+ +++ ++ S + L+S L
Sbjct: 453 IELGEIEAILGQHPALTQTLVIARDDVNGDKQLVAYIVASAEQIPSRVELRRFLQSQLPE 512
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P + ++++PL NGK+DR+ L
Sbjct: 513 YMVPAYFVFLDTLPLNPNGKIDRRAL 538
>UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide synthetase;
n=2; cellular organisms|Rep: Putative non-ribosomal
peptide synthetase - Nocardia farcinica
Length = 8426
Score = 215 bits (524), Expect = 5e-54
Identities = 154/451 (34%), Positives = 225/451 (49%), Gaps = 25/451 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFK-ESGVPFASF 78
++A+ A +AG AYVP++P+ P R+ HIL A P +V+ +A + +GVP
Sbjct: 1260 VVAMYAVLRAGGAYVPVDPAHPAERVGHILATAAPRVVLTTAAAGVAPAALPAGVPVHQV 1319
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+EL + + ++ D E APL D+ A V++TSGSTG PKGV +S+ AI N+L W
Sbjct: 1320 DEL--DLSGYAPTRIADHER-APLHPDNPAYVIFTSGSTGKPKGVSVSHRAIVNQLAWMH 1376
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLV 196
+ ++ + KTA TF S+ + PL G L + + + RDP+ L V
Sbjct: 1377 AEYRVRPG-DVYLQKTAATFDVSLWGYFLPLRAGATLRLAAPDGHRDPRYLAETIAADQV 1435
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ + S+L A L L+ GE L E + F + G L N YG
Sbjct: 1436 TLTDFVPSMLAVFAAHARRGELDSLREVFVIGEALPPETVAAFHAVC--DAG--LHNLYG 1491
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE +TY + +D P +PIG P N +Y+LD L P PGE+++AG
Sbjct: 1492 PTEAAVSITYREVTAADG----PLVPIGEPEWNSQVYVLDARLHPAPIGVPGELYLAGDQ 1547
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY G A+RF NP E R+YRTGD G ++Y GR D QVK RG
Sbjct: 1548 LARGYHGRVDLTADRFVANPFGRGGE--RMYRTGDLVRWSSDGELIYLGRVDFQVKFRGQ 1605
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPE----ILGFVTTKPGARTSAQHIEGKLR 429
R++L E+E AL P V + + +RG+ E ++G+V PGA + L
Sbjct: 1606 RIELAEIETALLAEPEVGQAAAALWSRERGSGEPGEHLVGYVVAAPGAEVDIDRLRAALT 1665
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P ++E+ PL +GK+DR+ L
Sbjct: 1666 RRLPAYMVPTALVELAEFPLNTSGKLDRRAL 1696
Score = 213 bits (520), Expect = 2e-53
Identities = 151/447 (33%), Positives = 231/447 (51%), Gaps = 28/447 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A AG Y+P++P P R HIL A P V+ + + +P A
Sbjct: 2335 VVGMYAVTVAGGGYLPLDPDLPAERTRHILDTAIPVAVLTAGT-------DLDLPVAQIR 2387
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + DAE APL + A VL+TSGSTG PKGV ++++A+ NRL W
Sbjct: 2388 IDRLDLERYPTTPVRDAERRAPLRAAHTAYVLFTSGSTGRPKGVAVAHAAVVNRLRWMQE 2447
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL--VL 197
+ +++ + KT +TF SV E + PL G L++ + + RDP+ L + R V
Sbjct: 2448 AYIALRPDDVLLQKTPVTFDVSVPEFFWPLQVGARLVLATPDGHRDPRYLAEVIRAEGVT 2507
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + S+L + L A+ RL+ +CSGE L A + G ++ N YG
Sbjct: 2508 VAHFVPSMLA-VFLAEAASGDTRLRHLLCSGEALPAATAQRAREL----TGARVHNLYGP 2562
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE +VT + + +D T+P+GRP+ N Y+LD L P PGE+++AGA L
Sbjct: 2563 TEAAVEVTCHEVTDADT----DTVPMGRPVWNTRAYVLDARLRPVPVGVPGELYLAGAQL 2618
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY+G +RF +P +P R+YRTGD + G + Y GRTD QVK+RG R
Sbjct: 2619 ARGYLGRADLTGDRFVADPF-DEPG-DRMYRTGDLVRWNRDGELEYLGRTDFQVKLRGLR 2676
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGKLRSALT 433
++L E+E AL VPGV++ VL P ++ +V +P A+ + +L L
Sbjct: 2677 IELGEIETALLAVPGVEQAAVLVRDDHGTGPRLVAYVVGVEP---VPAEGLRAELARRLP 2733
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P V + ++++PL +GK+DR L
Sbjct: 2734 GYMVPGVYVALDALPLNASGKLDRAAL 2760
Score = 212 bits (517), Expect = 4e-53
Identities = 157/450 (34%), Positives = 232/450 (51%), Gaps = 35/450 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A AG AYVP++P P R+ ++L+ A P V+ AD S+ P +
Sbjct: 4457 VVGMYAVTLAGGAYVPIDPEHPAERVEYVLRTARPVCVL-TAGADLSV---GTAPQVRVD 4512
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L S AD P+ DAE APL A VL+TSGSTG PKGV ++++AI NRL W
Sbjct: 4513 RLE---LSRFADGPIRDAERRAPLRPGHPAYVLFTSGSTGRPKGVAVAHAAIVNRLVWMQ 4569
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERL 195
+ +++ + KT TF SV E + PL G L++ + RDP L + ER+
Sbjct: 4570 DRYGLRP-DDVVLQKTPATFDVSVWEFFWPLQVGARLVVARPDGHRDPAYLARLTVDERV 4628
Query: 196 VLVPTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
V + + ++LA A R LRR+ SGE L +A + G ++ N
Sbjct: 4629 TTVHFVPSMLAVFLAEPAADRTGLRRV---FASGEALPAPIAQRARRVLGA----RVHNL 4681
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE DVT++ + +D +PIGRP+ N + +LD L P PGE+++AG
Sbjct: 4682 YGPTEAAVDVTFHEVTDADT----GAVPIGRPVFNTRLLVLDARLRPVPVGVPGELYLAG 4737
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIR 371
A LA GYV A RF +P + R+YRTGD + G + Y GRTD QVK+R
Sbjct: 4738 AQLALGYVARPDLTAERFVADPFGEPGD--RMYRTGDLVRWNRDGELEYLGRTDFQVKLR 4795
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGF-VTTKPGARTSAQHIEGKLRS 430
G R++L E+E AL +PG+++ VL G G ++G+ V T P + L +
Sbjct: 4796 GLRIELGEIETALTALPGIEQAAVLVRGTAGGEDTLVGYLVATDP----DLDAVRAALAA 4851
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++ +P+ +GK+DR L
Sbjct: 4852 RLPAYMVPAAFVVLDELPVNSSGKLDRAAL 4881
Score = 204 bits (499), Expect = 5e-51
Identities = 158/453 (34%), Positives = 229/453 (50%), Gaps = 32/453 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A KAG YVP++P P RI ++L A P LV+ + +P+ G+ A
Sbjct: 193 MVGMYAIHKAGGGYVPIDPEHPAERIAYVLDTAAPVLVLTTTADEPA-----GLGDARVL 247
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + A EP A P D++A V++TSGSTG PKGV +S+ ++ L W+ R
Sbjct: 248 RIDEFEAAPPAAEPELAPLPGP-HPDTVAYVIFTSGSTGRPKGVAVSHRSVMANLRWRQR 306
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
P +++ + KT TF SV E + PL G L I + RDP LV ER V
Sbjct: 307 LHPMR-PDDVVIQKTPFTFDVSVWEFFWPLQVGARLAIARPDGHRDPAYLVRFLAERGVT 365
Query: 198 VPTLLRSIL-MYLA-LGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + S+L M++A L + L L++ V SGE L A+ + G L N Y
Sbjct: 366 IAHFVPSMLAMFVAELASSGVALDALRMVVASGEALPAATAAA----LRDVSGATLQNTY 421
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE DVT + + +D + T+PIG D+ + +LDE L P GE+++AG
Sbjct: 422 GPTEATVDVTAHEVTAADTV----TVPIGTVADDNELLVLDESLRPVPTGVVGELYLAGV 477
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD---FGTLVKGAVL---YAGRTDAQ 367
LA GYV G A RF NPH E R+YRTGD +G G L Y GR D Q
Sbjct: 478 QLARGYVARPGLTAERFVANPHGAPGE--RMYRTGDLVRWGGGADGGPLELEYLGRIDFQ 535
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VK+RG R++L EVE AL + V + V+ G ++G+V G A +
Sbjct: 536 VKLRGLRIELGEVEAALLRSQQVAQAAVV-VRQHAGGDHLVGYVVPAGGPVDPAA-VLAV 593
Query: 428 LRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
R L YM+P +++V + +P+ NGK+DR L
Sbjct: 594 AREHLPEYMVPALVQVLDELPVNANGKLDRAAL 626
Score = 200 bits (488), Expect = 1e-49
Identities = 147/446 (32%), Positives = 219/446 (49%), Gaps = 22/446 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A +AG AY+P++P+ P R+ I++ A+P+LV+ AD GVP
Sbjct: 3396 LVAMYAIVRAGGAYLPLDPAHPADRLAQIVESAQPALVLVPVGAD---LPPLGVPVLRMA 3452
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L + A DA+ A L D+ A VL+TSGSTG PKGV +++ AI N+L W
Sbjct: 3453 DL--DLADAPARPVTDADRTAALRPDNTAYVLFTSGSTGRPKGVAVTHRAIMNQLRWLEH 3510
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ + ++ I + + LTF SV E + P+ G L+I + D ++ E +
Sbjct: 3511 RYQVTGADRI-LQRAPLTFDVSVWECFLPVAVGAPLVIAAPGAHLDLAAFADLLREHRIT 3569
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + S+L L L + C GE L+ +L + F DG + N YG
Sbjct: 3570 IAEYVPSVLAALIAEGMGDALASFRHLHCGGEALTPDLLTALRGVF---DG-AVHNAYGP 3625
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE Y+ +D + IGRP N +Y+LD L P PGE+++AG L
Sbjct: 3626 TEAAISAVYHEFTDADVAQ-GRDVAIGRPCWNTRVYVLDTRLRPVPIGVPGELYLAGNQL 3684
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY G A RF +P +YRTGD + G ++Y GR D QVK+RG R
Sbjct: 3685 ARGYHRRPGPTAERFVADPFGVPGSL--MYRTGDLVRWNRDGDLIYLGRNDFQVKLRGQR 3742
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E ALA VPGV V G ++G+V+ G SA + LR L
Sbjct: 3743 IELGEIEAALAAVPGVANAAVRVVADSAGRDALVGYVS---GDDLSAAAVLDVLRDRLPG 3799
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P ++ + +PL GK+DR L
Sbjct: 3800 YMVPAHLVVLAEMPLTTVGKLDRAAL 3825
Score = 195 bits (476), Expect = 3e-48
Identities = 151/458 (32%), Positives = 225/458 (49%), Gaps = 40/458 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A KAG AYVP++P P RI H+L A P+ ++ + D ++ + P + +
Sbjct: 5506 VVAMYAVLKAGGAYVPIDPDHPPLRIAHVLDTAAPAALLV--TTDVTLDYDG--PVVAVD 5561
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+A + AD+P+ E PL D+ A VL+TSGSTG PKGV +S++AI N++ W
Sbjct: 5562 TVALDGY---ADDPVAPEERRGPLHPDNPAYVLFTSGSTGKPKGVSVSHAAIVNQITWMQ 5618
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV-- 196
+ DS ++ + KTA TF S+ + PL G +++ S + RDP L +
Sbjct: 5619 SRYRL-DSGDVYLQKTATTFDVSLWGYFLPLRVGATVVLASPDGHRDPGYLAEVMGAYGV 5677
Query: 197 ----LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
VPT+L ++A + L L++ GE L E F +
Sbjct: 5678 TVTDFVPTMLAVFAGHVAESGQAAALAALRMVFVIGEALPGETVRAFTAI----SSAAVH 5733
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE +T+ + G PIG P N +Y+LD L PT GE+++
Sbjct: 5734 NLYGPTEAAVSITHREVTGETG---RAVAPIGNPEWNSRVYVLDSRLRPTLPGVAGELYL 5790
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKG---AVLYAGRTDA 366
AG LA GY G A+RF NP E R+YRTGD +G ++Y GRTD
Sbjct: 5791 AGVQLARGYHGRPALTADRFVANPFGAAGE--RMYRTGDLVRWETRGDTAELVYLGRTDF 5848
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVK RG R++L E+E LA VPGV G ++G++ P A +
Sbjct: 5849 QVKFRGQRIELGEIEAVLAAVPGVAGAAARVLG-----EHLVGYLLVAPEAADDHDAVLA 5903
Query: 427 KLRS----ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ R+ AL YM+P ++ ++ PL V+GK+DR L
Sbjct: 5904 RARAAAHEALPAYMVPGALLALDEFPLNVSGKLDRAAL 5941
Score = 193 bits (471), Expect = 1e-47
Identities = 139/448 (31%), Positives = 216/448 (48%), Gaps = 23/448 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A AGA YVP++P+ P R T +L A+P LV+ A + SG+
Sbjct: 7632 LVAMYAVLTAGAGYVPLDPAHPLERTTAVLAAADPELVLVSTRAPMLPERVSGLEIVL-- 7689
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++A T A E + P+ A V++TSGSTG PKGV + +A+ ++L W
Sbjct: 7690 DIAGIGTDVPAHPVRPYELVRPVHPADTAYVIFTSGSTGAPKGVVVPQAAVTHQLEWMQS 7749
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + + + T+ F SV E W G L++ RDPQ L+++ V
Sbjct: 7750 EYGLGADDAVLL-HTSAAFDLSVWEFWWAPRTGARLVLAPEGAHRDPQGLLDLLTYAAVT 7808
Query: 200 TLL----RSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
T+ + ++ G P +L V + + L ++ + G +L N Y
Sbjct: 7809 TVTLVPAQVAMLTEVAGERGLPAALRRLLV-----IGEALPTDTVRRTGESTQARLDNLY 7863
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE VT Y G+D+ PIG P +Y+LD+ L P GE+++ GA
Sbjct: 7864 GPTEATVSVTRY-RTGADEHGA--VAPIGAPEAGTRVYVLDDRLHPVPTGVVGELYLGGA 7920
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
LA GY A RF +P E RLYRTGD +G +++ R D QVK+RG
Sbjct: 7921 QLARGYHRRPDLTAERFVADPFGAPGE--RLYRTGDLVRWTAEGQLVFVQRRDFQVKVRG 7978
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
+R++L E+E AL P V + VVL +G ++G+VTT+ T + + L L
Sbjct: 7979 YRIELTEIEHALRAHPAVAEAVVLAHGAGGAEAMLVGYVTTRTPVDT--EDLRAALAGTL 8036
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P ++ ++++PL NGK+DR L
Sbjct: 8037 PGYMVPAALVRLDALPLTANGKLDRAAL 8064
Score = 152 bits (368), Expect = 4e-35
Identities = 130/448 (29%), Positives = 206/448 (45%), Gaps = 30/448 (6%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+AL A K GAA+VP++P++P RI H+L D+ +L + + A + ++
Sbjct: 6562 LALWAVAKTGAAFVPVDPTYPAERIAHMLTDSGAALGLTVERARAGLPGDTEWLVLDAAT 6621
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
A SA E + P+ +D A ++YTSGSTG+PKG ++++ I + Q
Sbjct: 6622 TAARLRHTSAAPVSPGELVRPVRTDDAAWMIYTSGSTGLPKGALVTHNGIAGVAYTQRDR 6681
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ--KLVNIERL--- 195
+ + + + + +F S+ E+ ++ L+I E + +L+ ER+
Sbjct: 6682 YDVTARTRV-LGVASPSFDASMLELLLAVVAAGTLVIAPPEVFAGAELTELMARERVSHA 6740
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ P++LR+ L PA P + GE E + + + DG + N Y
Sbjct: 6741 FITPSVLRT------LDPARLP--DFTHLIIGGEAFGTETVAAWAR-----DGRAVFNGY 6787
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T V S L + +G PL + +LD L P PGE+++ G
Sbjct: 6788 GPTE-----TTIVATVSPPLRPDRPVELGVPLAGMSAVVLDARLRPVPAGVPGELYLRGH 6842
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
LA GY G A RF +PH P RLYRTGD GA+ Y GR D QVK+RG
Sbjct: 6843 GLARGYHARPGLTAGRFVADPHG--PAGGRLYRTGDLACWTADGALRYLGRGDHQVKVRG 6900
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E++ LA P V V + + + + ++ +V G + AL
Sbjct: 6901 LRIELGEIDTVLAAHPSVRAAVTVGHAVAGEDVALVSYVVAAQGEIVDTAALLAHAARAL 6960
Query: 433 THYMMPQVIEV-ESIPLLVNGKVDRQGL 459
YM+P + V + +PL GK+DR L
Sbjct: 6961 PPYMVPAAVTVLDRLPLTPVGKLDRAAL 6988
>UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine
synthetase III) [Includes: ATP- dependent asparagine
adenylase (AsnA) (Asparagine activase); ATP- dependent
glutamine adenylase (GlnA) (Glutamine activase); ATP-
dependent tyrosine adenylase (TyrA) (Tyrosine activase);
ATP-dependent valine adenylase (ValA) (Valine activase);
ATP-dependent ornithine adenylase (OrnA) (Ornithine
activase); ATP-dependent leucine adenylase (LeuA)
(Leucine activase)]; n=8; cellular organisms|Rep:
Tyrocidine synthetase 3 (Tyrocidine synthetase III)
[Includes: ATP- dependent asparagine adenylase (AsnA)
(Asparagine activase); ATP- dependent glutamine adenylase
(GlnA) (Glutamine activase); ATP- dependent tyrosine
adenylase (TyrA) (Tyrosine activase); ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
ornithine adenylase (OrnA) (Ornithine activase);
ATP-dependent leucine adenylase (LeuA) (Leucine
activase)] - Brevibacillus parabrevis
Length = 6486
Score = 215 bits (524), Expect = 5e-54
Identities = 170/588 (28%), Positives = 276/588 (46%), Gaps = 48/588 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AY P++PS+P RI ++L D++ +++ +E
Sbjct: 1564 VVGMLAVLKAGGAYTPIDPSYPPERIQYMLSDSQAPILLTQRH-----LQELAAYQGEII 1618
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ +EA AD +D D +A V+YTSGSTG PKGV +S+ AICN + W
Sbjct: 1619 DVDEEAIYTGADTNLDNVA----GKDDLAYVIYTSGSTGNPKGVMISHQAICNHMLWMRE 1674
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
TFP + +E+ + KT +F SV E + PL+ G L++ + RD + + R +
Sbjct: 1675 TFPLT-TEDAVLQKTPFSFDASVWEFYLPLITGGQLVLAKPDGHRDIAYMTRLIRDEKIT 1733
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL + S+L + P L+ C GE L+ L S F++ +L N YG
Sbjct: 1734 TLQMVPSLLDLVMTDPGWSACTSLQRVFCGGEALTPALVSRFYE----TQQAQLINLYGP 1789
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE D TY+ + Y IPIG+P+DN +Y+++ GE+ +AG L
Sbjct: 1790 TETTIDATYWPCPRQQE---YSAIPIGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGL 1846
Query: 318 AAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHR 374
A GY + F DNP +P +YRTGD L G + Y GR D QVKIRGHR
Sbjct: 1847 ARGYWQREELTKASFVDNPF--EPG-GTMYRTGDMVRYLPDGHIEYLGRIDHQVKIRGHR 1903
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L Q V VV+ +G + +V + +T+ + L + L
Sbjct: 1904 IELGEIEATLLQHEAVKAVVVMARQDGKGQNSLYAYVVAEQDIQTA--ELRTYLSATLPA 1961
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P + +E +PL NGKVDR+ L +DA + + +
Sbjct: 1962 YMVPSAFVFLEQLPLSANGKVDRKAL-------PQPEDAAASAAVYVAPRNEWEAKLAAI 2014
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
+G + + F+ELGG+SL +++ I+ L+ R + V++ L E
Sbjct: 2015 WESVLGV-------EPIGVHDHFFELGGHSLKAMHVISLLQ-RSFQVDVP----LKVLFE 2062
Query: 554 VLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMVESSFYEKAELE 601
+ P A +++ T+TA+P ++ + + + + ++E
Sbjct: 2063 SPTIAGLAPLVAA-ARKGTYTAIPPVEKQEYYPVSAAQKRMFILQQME 2109
Score = 194 bits (473), Expect = 8e-48
Identities = 136/450 (30%), Positives = 230/450 (51%), Gaps = 33/450 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A++A ++GAAY+P++P +PQ RI ++L D++ +L++ P++ V +
Sbjct: 528 IVAIMAVLRSGAAYLPIDPEYPQDRIQYLLDDSQTTLLLTQSHLQPNIRFAGSVLYLDDR 587
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + ++ A E D +A ++YTSGSTG PKG +++ + N +WW +
Sbjct: 588 SLYEGGSTSFAPES---------KPDDLAYMIYTSGSTGNPKGAMITHQGLVNYIWWANK 638
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLIL----SRETTRDPQKLVNIERL 195
+ ++ + ++ ++++F +V I+ PLL G + + + D K + +
Sbjct: 639 VYVQGEAVDFPLY-SSISFDLTVTSIFTPLLSGNTIHVYRGADKVQVILDIIKDNKVGII 697
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
L PT L+ L+ G AS +RR ++ GE L +LA + + +FG + ++ N Y
Sbjct: 698 KLTPTHLK--LIEHIDGKAS-SIRR---FIVGGENLPTKLAKQIYDHFG--ENVQIFNEY 749
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE + Y+ + Q ++PIG P DN +YLLD + P GE+++AG
Sbjct: 750 GPTETVVGCMIYLYD--PQTTTQESVPIGVPADNVQLYLLDASMQPVPVGSLGEMYIAGD 807
Query: 316 NLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
+A GY +F DNP +P ++YRTGD L G + YAGR D QVKIRG
Sbjct: 808 GVAKGYFNRPELTKEKFIDNPF--RPG-TKMYRTGDLAKWLPDGNMEYAGRMDYQVKIRG 864
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
HR+++ E+E L Q V + VV+ + G + ++ ++ + + L L
Sbjct: 865 HRIEMGEIETRLTQHEAVKEAVVIVEKDESGQNVLYAYLVSE--RELTVAELREFLGRTL 922
Query: 433 THYMMPQ-VIEVESIPLLVNGKVDRQGLLK 461
YM+P I + IPL NGKV+R+ L K
Sbjct: 923 PSYMIPSFFIRLAEIPLTANGKVERKKLPK 952
Score = 169 bits (410), Expect = 3e-40
Identities = 128/453 (28%), Positives = 215/453 (47%), Gaps = 37/453 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AYVP++P +P+ R+ ++L D + LV+ + +
Sbjct: 2601 VVGILAILKAGGAYVPIDPEYPEERVAYMLTDCQARLVLTQKHLGAKLGSSVTAECLYLD 2660
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S +P++ T+ +A ++YTSG+TG PKGV + + I N + W+
Sbjct: 2661 DESNYGVHRSNLQPIN-------TASDLAYIIYTSGTTGKPKGVMVEHRGIVNNVLWKKA 2713
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIERLV 196
+ + + + F V + P+L G +++ E +DP +KL+ R
Sbjct: 2714 EYQMKVGDRSLL-SLSFAFDAFVLSFFTPVLSGATVVLAEDEEAKDPVSLKKLIAASRCT 2772
Query: 197 L---VPTLLRSILMYLALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L VP+L ++IL PA RPL+ + L GE ++ +L + + N D +
Sbjct: 2773 LMTGVPSLFQAILECST--PADIRPLQTVTL---GGEKITAQLVEKCKQL--NPD-LVIV 2824
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE T+ L G D I IGRP+ N ++Y++++ GE+ +
Sbjct: 2825 NEYGPTESSVVATWQRLAGPDA-----AITIGRPIANTSLYIVNQYHQLQPIGVVGEICI 2879
Query: 313 AGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
G LA GY +F +P A +R+Y+TGD G L G + Y GR D QVK
Sbjct: 2880 GGRGLARGYWNKPALTEEKFVSHPFAAG---ERMYKTGDLGKWLPDGTIEYIGRIDEQVK 2936
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG+R+++ E+E AL + VV+ Y G + + T + + L
Sbjct: 2937 VRGYRIEIGEIESALLAAEKLTAAVVVVYEDQLGQSALAAYFTA--DEQLDVTKLWSHLS 2994
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGLLK 461
L YM+P ++++ +PL NGKVD++ L K
Sbjct: 2995 KRLPSYMIPAHFVQLDQLPLTPNGKVDKKALPK 3027
Score = 169 bits (410), Expect = 3e-40
Identities = 152/529 (28%), Positives = 239/529 (45%), Gaps = 45/529 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I ++ KAG AY+ ++P P R+ ++L+D +V+ P + E +P E
Sbjct: 3639 ITGIMGILKAGGAYLGLDPEHPSERLAYMLEDGGVKVVLVQKHLLP-LVGEGLMPIVLEE 3697
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDS-IAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E + P D A + S +A V+YTSGSTG PKGV + + + RL
Sbjct: 3698 ESLR---------PEDCGNPAIVNGASDLAYVMYTSGSTGKPKGVMVEHRNV-TRLVMHT 3747
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+S+ + + A+ F EI+G LLHG +L ++S++ D +KL + R +
Sbjct: 3748 NYVQVRESDRM-IQTGAIGFDAMTFEIFGALLHGASLYLVSKDVLLDAEKLGDFLRTNQI 3806
Query: 199 PTLLRSILMYLALGPASRPL-RRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T+ + ++ L + + L+ + GE LS + + + ++ N YG
Sbjct: 3807 TTMWLTSPLFNQLSQDNPAMFDSLRALIVGGEALSPKHINRVKSALPD---LEIWNGYGP 3863
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T Y++E + IPIG+P+ N Y++D P PGE+ V G +
Sbjct: 3864 TENTTFSTCYLIEQHFE----EQIPIGKPIANSTAYIVDGNNQPQPIGVPGELCVGGDGV 3919
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GYV A +F NP A + +YRTGD L G + Y GR D QVKIRG+R
Sbjct: 3920 ARGYVNKPELTAEKFVPNPFAPG---ETMYRTGDLARWLPDGTIEYLGRIDQQVKIRGYR 3976
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L+Q V + VV G + + P A + + L
Sbjct: 3977 IELGEIETVLSQQAQVKEAVVAVIEEANGQKALCAYFV--PEQAVDAAELREAMSKQLPG 4034
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P +++E +PL NGKVDR+ L A VA D
Sbjct: 4035 YMVPAYYVQMEKLPLTANGKVDRRA-LPQPSGERTTGSAFVAAQNDTEAKLQQIWQ---- 4089
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
VLG A G + F+E+GG+SL ++ IT++ + + VE+
Sbjct: 4090 ------EVLGIPAIG---IHDNFFEIGGHSLKAMNVITQVH-KTFQVEL 4128
Score = 164 bits (398), Expect = 9e-39
Identities = 133/453 (29%), Positives = 213/453 (47%), Gaps = 34/453 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAG AYVP++P +PQ RI ++L+D+ +L++ P + + S
Sbjct: 5720 VIGILGILKAGGAYVPVDPGYPQERIQYLLEDSNAALLLSQAHLLPLLAQVSS-ELPECL 5778
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDS-IAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+L E D + L + + +A V+YTSG+TG PKGV + + I N L W+
Sbjct: 5779 DLNAEL-----DAGLSGSNLPAVNQPTDLAYVIYTSGTTGKPKGVMIPHQGIVNCLQWRR 5833
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLV---NI 192
+ + S++ + + F V ++ PLL G ++ +DP +KL+ +
Sbjct: 5834 DEYGFGPSDK-ALQVFSFAFDGFVASLFAPLLGGATCVLPQEAAAKDPVALKKLMAATEV 5892
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
VP+L ++IL + +L+ GE L +L K ++
Sbjct: 5893 THYYGVPSLFQAILDC----STTTDFNQLRCVTLGGEKLPVQLVQ---KTKEKHPAIEIN 5945
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE V S ++ I IGRPL N +Y++DE+ GE+ +
Sbjct: 5946 NEYGPTE-----NSVVTTISRSIEAGQAITIGRPLANVQVYIVDEQHHLQPIGVVGELCI 6000
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
GA LA GY+ A +F NP +P +R+Y+TGD G + Y GR D QVK
Sbjct: 6001 GGAGLARGYLNKPELTAEKFVANPF--RPG-ERMYKTGDLVKWRTDGTIEYIGRADEQVK 6057
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG+R+++ E+E A+ G+D+ VV+ D L A S + L
Sbjct: 6058 VRGYRIEIGEIESAVLAYQGIDQAVVVARDDDATAGSYLCAYFVAATA-VSVSGLRSHLA 6116
Query: 430 SALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLK 461
L YM+P +E++ +PL NGKVDR+ L K
Sbjct: 6117 KELPAYMIPSYFVELDQLPLSANGKVDRKALPK 6149
Score = 155 bits (377), Expect = 3e-36
Identities = 132/453 (29%), Positives = 217/453 (47%), Gaps = 35/453 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG +VP++P +P R +L+D+E L++ M + P+ +F
Sbjct: 4674 VIGMLAVLKAGGTFVPIDPDYPLERQAFMLEDSEAKLLL----TLQKMNSQVAFPYETFY 4729
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L E +E + E +A +++A ++YTSG+TG PKGV + + + N + + ++
Sbjct: 4730 -LDTETVDQ--EETGNLEHVAQ--PENVAYIIYTSGTTGKPKGVVIEHRSYAN-VAFAWK 4783
Query: 140 TFPYSDSEEICVWKTA-LTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER---- 194
+ DS + + + A F S + LL G L+I DP L R
Sbjct: 4784 DEYHLDSFPVRLLQMASFAFDVSTGDFARALLTGGQLVICPNGVKMDPASLYETIRRHEI 4843
Query: 195 --LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
P L+ ++ Y+ + ++KL + ++ E FG + ++
Sbjct: 4844 TIFEATPALIMPLMHYVYENELD--MSQMKLLILGADSCPAEDFKTLLARFGQK--MRII 4899
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE D +YY E +D + T+PIG+PL N +Y++D L+ GE+
Sbjct: 4900 NSYGVTEACIDTSYY--EETDVTAIRSGTVPIGKPLPNMTMYVVDAHLNLQPVGVVGELC 4957
Query: 312 VAGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+ GA +A GY+ +F NP A +RLYRTGD G V + GR D QV
Sbjct: 4958 IGGAGVARGYLNRPELTEEKFVPNPFAPG---ERLYRTGDLAKWRADGNVEFLGRNDHQV 5014
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRG-NPEILGFVTTKPGARTSAQHIEGK 427
KIRG R++L E+E L ++ G+ + VV+ DRG E+ +V T+ +
Sbjct: 5015 KIRGVRIELGEIETQLRKLDGITEAVVVARE-DRGQEKELCAYVVADHKLDTA--ELRAN 5071
Query: 428 LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L L M+P + ++++PL NGKVDR+ L
Sbjct: 5072 LLKELPQAMIPAYFVTLDALPLTANGKVDRRSL 5104
>UniRef50_Q39GN5 Cluster: Non-ribosomal peptide synthase; n=16;
Burkholderia|Rep: Non-ribosomal peptide synthase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 3219
Score = 214 bits (523), Expect = 7e-54
Identities = 146/457 (31%), Positives = 229/457 (50%), Gaps = 33/457 (7%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYD----DSADPSMFKESG 72
F +MAL+ KAGAAY+P++P +P RI ++L+DA P++ I + + ++ ++
Sbjct: 2673 FDMVMALVGVLKAGAAYLPVDPDYPAERIAYMLRDARPAVAITQAHLREQVEAALGDDAT 2732
Query: 73 VPFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN 132
+ +L + T A A + +A ++YTSGSTG PKG ++ A+ N
Sbjct: 2733 TQLLTVADLLADETEGDA-----AGATTTIDDAQLAYLIYTSGSTGKPKGAGNTHGALAN 2787
Query: 133 RLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV-- 190
R+ W + + +++ + KT F SV E PL G L I + RDP +L
Sbjct: 2788 RIAWMQHAYRLT-RDDVVLHKTPFGFDVSVWEFVWPLAIGAKLAIAAPGDHRDPARLAAA 2846
Query: 191 ----NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNE 246
+ L VP++L + YL A+ ++L V SGE L+ EL ++ + N
Sbjct: 2847 IHAHGVTVLHFVPSMLAAFAAYLDDFSAAAQCDSVRLIVASGEALAPELVAKMARLLPNA 2906
Query: 247 DGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSE 306
L N YG TE DV+++ G D + +PIG P+ N +++LD P
Sbjct: 2907 ---TLVNLYGPTEAAIDVSHWTC-GPDDANAV-AVPIGHPIANLQLHVLDASWQPVPAGA 2961
Query: 307 PGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGR 363
GE+++AGA LA GY+G A RF +P R+YRTGD GA+ Y GR
Sbjct: 2962 TGELYLAGAGLARGYLGRPALTAERFVPDPFVPG---ARMYRTGDLARRRADGALDYLGR 3018
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQH 423
D QVK+RG R++ E+E L PGV+ VV+ + +++G+V
Sbjct: 3019 VDTQVKLRGQRIEPGEIEALLRAAPGVNDAVVIV-----RDEQLIGYVARGDAGPLDRTA 3073
Query: 424 IEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ LR+ L YM+P Q+IE++++P+ NGK DR L
Sbjct: 3074 LLDALRAQLPAYMVPSQLIELDALPVTPNGKCDRHAL 3110
Score = 138 bits (334), Expect = 5e-31
Identities = 154/571 (26%), Positives = 244/571 (42%), Gaps = 51/571 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGA V ++P+ P R+ D + A+P+ + +G+ +
Sbjct: 1143 VVGLLGALKAGALAVLLDPAQPAARLAAAAADCGARWALV---AEPAAWP-TGIDAQPLD 1198
Query: 80 --ELAQEAT-SHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
LAQ+AT +H+A +AP A ++YTSGSTG PKGV +S+ A+ + +
Sbjct: 1199 VDTLAQDATLAHAA-----GVRIAPHPEQG-AYLIYTSGSTGTPKGVVVSHGALADYVQG 1252
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER-- 194
++ + T + ++G L GR L +L DP + R
Sbjct: 1253 MLDELAFAPDASFAMVSTVAADLGHT-TLFGALCAGRTLHLLPAACAFDPDLFADEMRRR 1311
Query: 195 ----LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
L +VP+ L+++L A PA L R L V GETL+ L + + +
Sbjct: 1312 DVGVLKIVPSHLQALLD--ARVPAD-VLPRHAL-VTGGETLTWALVA---RLAALAPACR 1364
Query: 251 LANFYGSTE-VMGDVTYYVLE-GSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPG 308
+ N YG TE +G + +D D +P+G+PL N +LD + G
Sbjct: 1365 VINHYGPTEATVGAIACDTASIAADARDPASGVPLGQPLPNARALVLDAFGACVPAGATG 1424
Query: 309 EVWVAGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTD 365
E+++ G +A GY+G A RF +P RLYRTGD L V G + + GR D
Sbjct: 1425 ELYLGGPGVARGYLGRPAQTAERFVPDPFTPG---ARLYRTGDRVRLRVDGRLAFLGRID 1481
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
QVKIRG+RV+ EV A+ + + L D G + FV + GA +
Sbjct: 1482 DQVKIRGYRVEPGEVSAAVRAAGPIAQAETLAIEHD-GRLRLATFVVMRDGANFDEAAVR 1540
Query: 426 GKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXX 484
L + L YM+P Q + + +P+ NGK+DR L ++ A + +
Sbjct: 1541 AALAAKLPDYMVPAQFVALARLPVTANGKIDRAALREL-----------AAAPVATASGD 1589
Query: 485 XXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISD 544
AVL +A + + F+ELGG+S+ + I + R RG
Sbjct: 1590 GPQGAVETVLAEVWQAVL-KAPK--VGRNDNFFELGGDSILVLQVIARARKRGVRFTPKQ 1646
Query: 545 FLGASTLGEVLSKMSTDPNGGADSKEATFTA 575
T+ E+ T+ A + + A
Sbjct: 1647 LFDGPTVAELARIAKTEDVAAAAAVQPAVAA 1677
Score = 115 bits (276), Expect = 6e-24
Identities = 126/453 (27%), Positives = 199/453 (43%), Gaps = 37/453 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ALLA KAG +VP++P P R+ I++DA+ I D + ++ G PF +
Sbjct: 74 VALLAVLKAGGVFVPLDPRHPAARLDWIVQDAQLRHGIVDAAGRAAL----GEPFEHAFD 129
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
+A D E L + S A ++YTSGSTG PK V + + +
Sbjct: 130 ATVDAADGQEIVADDEEVL--VHPRSAAYMIYTSGSTGTPKAVVVEHGPLAAHCDALAAA 187
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRET-TRDPQKLVNIERLVLV 198
P + + + ++ F D+ E W PL G ++++ + D + + V V
Sbjct: 188 LPIEAGDRLLHF-ASVNF-DAAHECWLAPLATGASIVVAPPQPFAPDAAHALLVSESVNV 245
Query: 199 PTLLRSILM-YLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ L + A+ L++ GE L ++ A EF + G +L N YG
Sbjct: 246 AAFPPAYLREFAAVAARDGVPPALRVLAFGGEALPQQ-AFEFVR--GTFPSVRLINGYGP 302
Query: 258 TE-VMGDVTYYVLEGSDQL----DLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
TE V+ + + V G + D Y ++PIGR + + E+ GE+ +
Sbjct: 303 TEAVISPMLWPVEPGETPVLAADDAYASLPIGRVIGPRVARIDGGEVDGV-----GELLL 357
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
G +A GY G A RF P A R+YRTGD L GA Y GR D QV+
Sbjct: 358 GGVCVARGYHGRPALTAERFI--PDADGEPGARVYRTGDLARLRDDGAFDYLGRLDDQVQ 415
Query: 370 IRGHRVDLLEVERALAQVPGV-DKCVVLCYGLDRGNPEILGFVTTKPGARTSA--QHIEG 426
+RG RV+ E+ L P V D VV G G ++ V + A +A H+
Sbjct: 416 VRGVRVEPAEIAACLRSHPAVADAAVVAETG--NGPTRLIACVALRAAADDAALKAHVAA 473
Query: 427 KLRSALTHYMMPQVIEVESIPLLVNGKVDRQGL 459
+L +A + + + +++P +NGK+DR L
Sbjct: 474 QLPAA---WQPHRFVRCDALPYTLNGKIDRAAL 503
>UniRef50_Q84DH9 Cluster: Peptide synthase; n=3; Streptomyces|Rep:
Peptide synthase - Streptomyces ansochromogenes
Length = 677
Score = 214 bits (523), Expect = 7e-54
Identities = 177/535 (33%), Positives = 273/535 (51%), Gaps = 49/535 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I ALL K GAAYVP++P +P R+ ++L D L++ ++ P +F + +
Sbjct: 136 ITALLGVLKTGAAYVPLDPEYPVERLRYVLSDTGARLLLTQEALRP-LFPDHDGEILCLD 194
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ Q+ + SA D+ PL SD+ A V++TSGSTG PKGV +++ ++ N R
Sbjct: 195 QHRQDIDALSAAPAPDSPV--PLPSDT-AYVIHTSGSTGRPKGVLVTHRSLANHSSAVNR 251
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILS---RETTRD-PQKLVNIERL 195
F ++ + + + L+F + EI+ PLLHG AL++ S R+T R Q++++
Sbjct: 252 YFAFAPGDRVLQCRP-LSFDAAAEEIFPPLLHGAALVLGSDPLRQTFRALTQQVIDTGTT 310
Query: 196 VL-VPTLL-------RSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
L VPT L+ LA A R + + +GE +++ + K G +
Sbjct: 311 FLSVPTAFWHSWVAEEDCLLRLATESALRTM------IVAGEKATRQALLTWKKRVGED- 363
Query: 248 GYKLANFYGSTEVMGDVTYYVLE-GSD-QLDLYPTIPIGRPLDNCAIYLLDEELSPTRDS 305
+ N YG TE G +T V E G+D ++ Y ++PIGRP+DN Y+LD+ L P
Sbjct: 364 -IRWFNVYGPTE--GTITTTVHEPGADWEIGEYGSVPIGRPIDNVRTYVLDDALRPVPAG 420
Query: 306 EPGEVWVAGANLAAGYVGG--GGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAG 362
EPGE+++ GA +A GY+ A RF +P + P RLYRTGD G + + G
Sbjct: 421 EPGELFIGGAGVAVGYLNAPQTTAERFLPDPFSGVPG-SRLYRTGDLVRADADGCLEFLG 479
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R D QVK+RG+R++L E+E L + V CV L G D + ++ FVT A A
Sbjct: 480 RRDHQVKLRGYRIELGEIEAVLTEHEDVRACVALVTG-DGPDSALVCFVTAGGRAAPPAA 538
Query: 423 HIEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCS 481
+ LR L YM+P + V ++ PL NGK+DR LL + +DD E AV I
Sbjct: 539 ELIAHLRGRLPWYMIPTAVHVLDAFPLTPNGKIDRAALLAL----EPDDDGE-AVHI--- 590
Query: 482 XXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR 536
+LGR RG +S+ + F+++GG+SL + I ++R R
Sbjct: 591 ---APRTPEEAVLADIWEDILGR--RG-ISVDADFFQVGGHSLLAASLIARIRAR 639
>UniRef50_Q5DIP4 Cluster: PvdJ; n=19; root|Rep: PvdJ - Pseudomonas
aeruginosa
Length = 4991
Score = 214 bits (523), Expect = 7e-54
Identities = 168/552 (30%), Positives = 264/552 (47%), Gaps = 55/552 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL+A KAG AYVP++P +P+ R ++L+D+ L++ + + GV +
Sbjct: 3151 VVALMAILKAGGAYVPVDPEYPEERQAYMLEDSGVQLLLSQSHLKLPLAQ--GVQRIDLD 3208
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +H+ + P L +++A V+YTSGSTG PKG +SA+ NRL W +
Sbjct: 3209 QADAWLENHAENNPG-----VELNGENLAYVIYTSGSTGKPKGAGNRHSALSNRLCWMQQ 3263
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+ + + + KT +F SV E + PL+ G L++ + RDP KLV ++
Sbjct: 3264 AYGLGVGDTV-LQKTPFSFDVSVWEFFWPLMSGARLVVAAPGDHRDPAKLVALINREGVD 3322
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L++ L + + LK VCSGE L + + F Y N
Sbjct: 3323 TLHFVPSMLQAFLQDEDVASCTS----LKRIVCSGEALPADAQQQVFAKLPQAGLY---N 3375
Query: 254 FYGSTEVMGDVTYY--VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
YG TE DVT++ V EG D +PIGRP+ N A Y+LD L P GE++
Sbjct: 3376 LYGPTEAAIDVTHWTCVEEGKD------AVPIGRPIANLACYILDGNLEPVPVGVLGELY 3429
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+AG LA GY G A RF +P +R+YRTGD G + YAGR D QV
Sbjct: 3430 LAGRGLARGYHQRPGLTAERFVASPFVAG---ERMYRTGDLARYRADGVIEYAGRIDHQV 3486
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L E+E L + P V + VL +++G+V + + + L
Sbjct: 3487 KLRGLRIELGEIEARLLEHPWVREAAVLAV----DGKQLVGYVVLESEGGDWREALAAHL 3542
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
++L YM+P Q + +E +PL NGK+DR+ L K+ + A + +
Sbjct: 3543 ATSLPEYMVPAQWLALERMPLSPNGKLDRKALPKIEAEDGLGEYVAPASEPERQLAAIWA 3602
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
VLGR G + F+ LGG+S+ SI +++ R G + D
Sbjct: 3603 D------------VLGRERVG---VTDNFFALGGDSIVSIQVVSRARQAGLQLSPRDLFQ 3647
Query: 548 ASTLGEVLSKMS 559
+ ++ + S
Sbjct: 3648 LQNIRKLAERCS 3659
Score = 210 bits (514), Expect = 8e-53
Identities = 167/532 (31%), Positives = 258/532 (48%), Gaps = 43/532 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LLA KAG AYVP++P +P R+ ++++D+ L++ +A + G+P +
Sbjct: 1634 IVGLLAILKAGGAYVPLDPRYPSDRLGYMIEDSGIRLLLTQRAARERLPLGEGLPCLLLD 1693
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + +P A + D++A V+YTSGSTG PKG L + +
Sbjct: 1694 A-EHEWAGYPESDPQSAVGV-----DNLAYVIYTSGSTGKPKGTLLPHGNVLRLFDATRH 1747
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLV 196
F +S + ++ + F SV EI+G LLHG L+I+ ET+R P+ + + ER+
Sbjct: 1748 WFGFSADDAWSLFHS-YAFDFSVWEIFGALLHGGRLVIVPYETSRSPEDFLRLLCRERVT 1806
Query: 197 LV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
++ P+ + ++ G PL L+ V GE L + +F+ FG+ +L N
Sbjct: 1807 VLNQTPSAFKQLMQVACAGQEVPPLA-LRHVVFGGEALEVQALRPWFERFGDR-APRLVN 1864
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTY L +D LD PIG P+ + + YLLD L+P GE++V
Sbjct: 1865 MYGITETTVHVTYRPLSLAD-LDGGAASPIGEPIPDLSWYLLDAGLNPVPRGCIGELYVG 1923
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
GA LA GY+ RF +P +T RLYRTGD G V Y GR D QVKI
Sbjct: 1924 GAGLARGYLNRPELSCTRFVADPFSTTGG--RLYRTGDLARYRCDGVVEYVGRIDHQVKI 1981
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA---QHIEGK 427
RG R++L E+E L PGV + VVL + G +++G+V T+ A +
Sbjct: 1982 RGFRIELGEIEARLLAQPGVAEAVVLPHE-GPGATQLVGYVVTQAAPSDPAALRDTLRQA 2040
Query: 428 LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L+++L +M+P ++ +E +PL NGK+DR+ L D S
Sbjct: 2041 LKASLPEHMVPAHLLFLERLPLTANGKLDRRALPAP----------------DASRLQRD 2084
Query: 487 XXXXXXXXXXTVGAVLGRAAR-GTLSLRSGFYELGGNSLNSIYTITKLRDRG 537
+ A+ + G + L F+ELGG+S+ SI +++ R G
Sbjct: 2085 YTAPRSELEQRLAAIWADVLKLGRVGLDDNFFELGGDSIISIQVVSRARQAG 2136
Score = 175 bits (426), Expect = 4e-42
Identities = 141/453 (31%), Positives = 224/453 (49%), Gaps = 32/453 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AYVP++P +P R+ +++ D+ L++ S + + G+ +
Sbjct: 576 VVALLAVLKAGGAYVPLDPQYPADRLQYMIDDSGLRLLLSQQSVLARLPQSDGLQSLLLD 635
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L + + A+ P E AP DS+ +YTSGSTG PKGV + + A+ N + R
Sbjct: 636 DLERLVHGYPAENPDLPE--AP---DSLCYAIYTSGSTGQPKGVMVRHRALTNFVCSIAR 690
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P + + + T +F E++ PL G ++L+ SRE +DP+ L+++ V
Sbjct: 691 Q-PGMLARDRLLSVTTFSFDIFGLELYVPLARGASVLLASREQAQDPEALLDLVERQGVT 749
Query: 200 TLLRSILMYLALGPASR-PLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L + + L + R L R +C GE L+++LA + N YG T
Sbjct: 750 VLQATPATWRMLCDSERVDLLRGCTLLCGGEALAEDLAVRMRGLSAST-----WNLYGPT 804
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + L G + +G PL+N A+Y+LD E++P GE+ + G LA
Sbjct: 805 ETTIWSARFRL-GEEARPF-----LGGPLENTALYILDSEMNPCPPGVAGELLIGGDGLA 858
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
GY G A RF +P A + RLYRTGD G + Y GR D QVKIRG R+
Sbjct: 859 RGYHRRPGLTAERFLPDPFAA--DGSRLYRTGDLARYRADGVIEYLGRIDHQVKIRGFRI 916
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP---GARTSAQH-----IEGK 427
+L E+E L + V + VV+ G + V T+ GA ++ Q ++
Sbjct: 917 ELGEIETRLLEQDSVREAVVVAQPGVAGPTLVAYLVPTEAALVGAESARQQELRSALKNS 976
Query: 428 LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L + L YM+P ++ +E++PL NGK++R+ L
Sbjct: 977 LLAVLPDYMVPAHMLLLENLPLTPNGKINRKAL 1009
Score = 151 bits (365), Expect = 9e-35
Identities = 144/539 (26%), Positives = 242/539 (44%), Gaps = 44/539 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AYVP++ ++P+ R+ ++++D+ +L++ + A + +GVP + +
Sbjct: 4200 VVALLAVLKAGGAYVPLDLAYPRERLAYLMQDSGIALLLSESQALVQLPVPAGVPALALD 4259
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + H A P + ++A V+YTSGSTG+PKGV +S+ + +
Sbjct: 4260 RL--DLLEHPAQAPQ-----VEVHPANLAYVIYTSGSTGLPKGVAVSHGPLAMHIDAVGE 4312
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLL-HGRALLILSRETTRDPQKLVNIERLVLV 198
+ + ++ + + F D E W L HG +LL+ Q ++R +
Sbjct: 4313 RYEMTPADRELHFMS-FAF-DGAHERWLTALGHGGSLLLRDDALWTPEQTYAAMQRHGVT 4370
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWV-CSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + A R + + C G E K + Y + N YG
Sbjct: 4371 VAAFPPVYLQQLAEHAERDGNPPPVRIYCFGGDAVPVAGFELAKR-ALKPRY-IINGYGP 4428
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTI-PIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE + VT + + + + PIG + Y+LD +L+P GE+++ G
Sbjct: 4429 TETV--VTPLIWKAAMDTECGAAYAPIGSFVGERCGYVLDADLNPLPAGVAGELYLGGVG 4486
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY+ G A RF NP + E RLYRTGD + G Y GR D QVK+RG
Sbjct: 4487 LARGYLQRPGLSAERFVANPFSRTGE--RLYRTGDLVRQREDGTFDYLGRIDNQVKVRGF 4544
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA--QHIEGKLRSA 431
R++L E+E L V + VV+ G ++LG+V + GA S + + +L+
Sbjct: 4545 RIELGEIEARLQDAGEVREAVVVARDAASGK-QLLGYVVAEDGADASGLLERLRERLKRD 4603
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L YM+P + + ++PL NGK+DR+ L DID +
Sbjct: 4604 LPEYMVPAHLALLPAMPLTPNGKIDRKAL----------------PDIDVTASEAYVAPR 4647
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITK---LRDRGYYVEISDFL 546
G + + F+ELGG+S+ S+ + K L+ G+ +++ D +
Sbjct: 4648 NELELALAGIWQEVLGIARIGVHDNFFELGGDSILSMQVVAKARALKKLGFSLKLRDLI 4706
>UniRef50_Q0MYM1 Cluster: Nonribosomal peptide synthetase; n=2;
Listonella anguillarum|Rep: Nonribosomal peptide
synthetase - Vibrio anguillarum (Listonella anguillarum)
Length = 2836
Score = 214 bits (523), Expect = 7e-54
Identities = 155/462 (33%), Positives = 238/462 (51%), Gaps = 42/462 (9%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+A+ + + GAAY+P++ +P R+ +++ DA+P+L+I S + FE
Sbjct: 2049 LAIYSIIECGAAYLPLDVGYPDERLAYMINDAKPALIITCSSFT-----------SRFEG 2097
Query: 81 LAQEATSHSADEPMDAET---LAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
LA P+ AE LT + A +LYTSGSTG PKGV +S+ AI NRL W
Sbjct: 2098 LATLLLLDKLPAPVRAERQNRADGLTPSNAAYLLYTSGSTGNPKGVLVSHQAIVNRLKWM 2157
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------N 191
+P S SE++ + KT +F SV E + PLL G +L++ E +DP+ L+ +
Sbjct: 2158 QHQYPLS-SEDVVLQKTPCSFDVSVWEFFWPLLEGASLVMAPAEAHKDPEWLLQIIDDYH 2216
Query: 192 IERLVLVPTLLRSILMYL-ALGPASRPLR-RLKLWVCSGETLSKELASEFFKYFGNEDGY 249
+ + VP++L + + + A P + LK CSGE L+KEL ++ +
Sbjct: 2217 VTTMHFVPSMLAAFMASIEANQPTGFTVAPSLKQVFCSGEALAKELCHQYARRI----NA 2272
Query: 250 KLANFYGSTEVMGDVTYYVLEGSD-QLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPG 308
L N YG TE DVTYY G + + PIG P+ N +Y+LD L PG
Sbjct: 2273 PLHNLYGPTEAAVDVTYYPAYGEALNASVGRSAPIGLPVWNTQVYVLDSFLRAVPIGVPG 2332
Query: 309 EVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTD 365
E+++AG LA GY A+RF NP +R+YRTGD L G++ Y GR+D
Sbjct: 2333 ELYLAGEQLAIGYFNRSALTADRFIANPFTCG---ERMYRTGDVVRWLACGSIEYLGRSD 2389
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLD-------RGNPEILGFVTTKPGAR 418
Q+KIRG RV+L E+E AL +P V + VV L +I+G+V +
Sbjct: 2390 DQIKIRGQRVELGEIESALQALPAVKQAVVCAQTLSTHSGMLGADERQIIGYVIAHDMSV 2449
Query: 419 TSAQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
T+ + + +L L +M+P ++ ++ PL +GK+D++ L
Sbjct: 2450 TNGEKLRAELSEHLPAHMVPAAIVLLDHYPLSASGKLDKKAL 2491
Score = 157 bits (381), Expect = 1e-36
Identities = 163/591 (27%), Positives = 263/591 (44%), Gaps = 72/591 (12%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEP-SLVIYDDSADPSMFKESGVPFAS 77
+++ +LA +AGA Y+P++ +P RI I++ A P LV+ +D + + S VP
Sbjct: 530 SVVTMLAILRAGAIYLPIDLDYPVERIESIVEQARPWCLVVEEDEQNMAYSSISYVP--R 587
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW-W 136
F L + A H+A +P ++ +A +++TSGSTG PKGV ++ A+ N L
Sbjct: 588 FIALPELARIHTAPQPKPT-----ISHSDVAYIIFTSGSTGHPKGVMNTHGALLNLLRSH 642
Query: 137 QFRTFPYSDS---------EEICVWKTALTFVDSVCEIWGP---LLHGRALLILSRETTR 184
Q F + E+ + A T S W +L G + + E +
Sbjct: 643 QGSIFSAAIRKLATRRQLPEQAITVRAAHTTSFSFDASWEQVLWMLSGHTMYLYDDEQRK 702
Query: 185 DPQKLV------NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASE 238
D +LV NI+ L L P L +L + P L + E + ++L S
Sbjct: 703 DAYELVQCVAEDNIDALDLPPLLFDQMLDSGLMTNDHVPT----LVLIGSEAIPQKLWSR 758
Query: 239 FFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEE 298
++ + NFYG TE D S LD + IGRP+ +Y+LDE
Sbjct: 759 VSEF----PELLVENFYGPTEFTVDAI------SASLDADASPVIGRPIAGACVYVLDEN 808
Query: 299 LSPTRDSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG 356
L P E GE++++GA LA GY+ A RF NP A + +YRTGD
Sbjct: 809 LEPVAIGEVGELYLSGAGLAKGYLNQPSMTAERFVANPFAYG---KIMYRTGDLVKWRDN 865
Query: 357 AVL-YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP 415
+L + GR D Q+KIRG R++L VE A+ + GV+ VV+ + +L + T +
Sbjct: 866 GLLDFVGRCDHQIKIRGFRIELGNVESAINAIDGVNTTVVVAEPVG-DTHRLLAYCTLEK 924
Query: 416 GARTSA-------QHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTN 467
G + + Q ++ + AL YM P V+ +++ L VNGK+DR+ L K T
Sbjct: 925 GTQGESVQPAFTEQRLQSLIAQALPDYMQPTNVMILDAFSLNVNGKIDRKALPKYSAGTR 984
Query: 468 NNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSI 527
+ A + + +LG + G + F+ LGG+S++++
Sbjct: 985 SERVAPI-------------TQPEQLLCDAITELLGVSDVG---MSDDFFNLGGDSISAM 1028
Query: 528 YTITKLRDRGYYVEISDFLGASTLGEVLSKMSTDPNGGADSKEATFTAVPM 578
T+LR GY + A LG + +M+ + +E +PM
Sbjct: 1029 SLGTRLRTAGYDLRPKAIFAARQLGMMAGQMAPLQQQQREKQEGIIRPLPM 1079
>UniRef50_P45745 Cluster: Dimodular nonribosomal peptide synthetase;
n=25; Bacillus|Rep: Dimodular nonribosomal peptide
synthetase - Bacillus subtilis
Length = 2378
Score = 214 bits (522), Expect = 9e-54
Identities = 146/451 (32%), Positives = 227/451 (50%), Gaps = 18/451 (3%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE- 79
+ LLA KAGAAY+P++P +P RI +LKDA+P+ ++ + A + VP +
Sbjct: 1579 VGLLAVLKAGAAYLPLDPDYPADRIAFMLKDAQPAFIMTNTKAANHIPPVENVPKIVLDD 1638
Query: 80 -ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
ELA++ ++ A P + + PL+ + A V+YTSGSTG+PKGV + + +
Sbjct: 1639 PELAEKLNTYPAGNPKNKDRTQPLSPLNTAYVIYTSGSTGVPKGVMIPHQNVTRLFAATE 1698
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERL 195
F +S S +I + F SV EIWGPLLHG L+I+ +R P+ + + E +
Sbjct: 1699 HWFRFS-SGDIWTMFHSYAFDFSVWEIWGPLLHGGRLVIVPHHVSRSPEAFLRLLVKEGV 1757
Query: 196 VLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
++ P+ + P L+ + GE L +++ E+ +L
Sbjct: 1758 TVLNQTPSAFYQFMQAEREQPDLGQALSLRYVIFGGEALELSRLEDWYNRH-PENRPQLI 1816
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE V+Y L+ S L IG + + +Y+LDE L P GE++V
Sbjct: 1817 NMYGITETTVHVSYIELDRS-MAALRANSLIGCGIPDLGVYVLDERLQPVPPGVAGELYV 1875
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
+GA LA GY+G G + RF +P P R+YRTGD L G++ Y GR D QVK
Sbjct: 1876 SGAGLARGYLGRPGLTSERFIADPFG--PPGTRMYRTGDVARLRADGSLDYVGRADHQVK 1933
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG R++L E+E AL Q P ++ V+ G+ + +V +A+ +
Sbjct: 1934 IRGFRIELGEIEAALVQHPQLEDAAVIVREDQPGDKRLAAYVIPSEETFDTAE-LRRYAA 1992
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++ +PL NGK+DR+ L
Sbjct: 1993 ERLPDYMVPAAFVTMKELPLTPNGKLDRKAL 2023
Score = 195 bits (475), Expect = 4e-48
Identities = 140/460 (30%), Positives = 227/460 (49%), Gaps = 27/460 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ++L K GAAY+P++P FP RI+++L+DA+PS +I + S+ + VP +
Sbjct: 522 VASMLGVLKTGAAYLPLDPEFPADRISYMLEDAKPSCIITTEEIAASLPDDLAVPELVLD 581
Query: 80 E-LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + QE + E D ++ D A ++YTSGSTG PKGV ++ ++ N L
Sbjct: 582 QAVTQEIIKRYSPENQDVS----VSLDHPAYIIYTSGSTGRPKGVVVTQKSLSNFLLSMQ 637
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVL 197
F + + + T + F S E++ PL+ G ++I +ET R+PQ L IE +
Sbjct: 638 EAFSLGEEDRLLA-VTTVAFDISALELYLPLISGAQIVIAKKETIREPQALAQMIENFDI 696
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L + + LR L++ V GE L L E + + N YG
Sbjct: 697 NIMQATPTLWHALVTSEPEKLRGLRVLV-GGEALPSGLLQEL-----QDLHCSVTNLYGP 750
Query: 258 TE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE + ++ EG L PIG+P+ N +Y+LD L P GE+++AG
Sbjct: 751 TETTIWSAAAFLEEG-----LKGVPPIGKPIWNTQVYVLDNGLQPVPPGVVGELYIAGTG 805
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
LA GY A RF +P+ P R+YRTGD G++ Y GR D Q+KIRG
Sbjct: 806 LARGYFHRPDLTAERFVADPYG--PPGTRMYRTGDQARWRADGSLDYIGRADHQIKIRGF 863
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E++ LA P +++ V+ G+ + +V T+ + + ++L
Sbjct: 864 RIELGEIDAVLANHPHIEQAAVVVREDQPGDKRLAAYVVADAAIDTA--ELRRYMGASLP 921
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDA 472
YM+P +E++ +PL NGK+DR+ L +T+ +D A
Sbjct: 922 DYMVPSAFVEMDELPLTPNGKLDRKALPAPDFSTSVSDRA 961
>UniRef50_Q0S6F2 Cluster: Non-ribosomal peptide synthetase; n=2;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Rhodococcus sp. (strain RHA1)
Length = 6278
Score = 213 bits (521), Expect = 1e-53
Identities = 154/446 (34%), Positives = 225/446 (50%), Gaps = 23/446 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A KAG AYVP++P P R+ +++ A+P LV+ SAD + +GV +
Sbjct: 1841 LVGIYAVVKAGGAYVPIDPGQPAERVGYVVGIADPVLVL-TSSAD-RVVVPAGVRVVELD 1898
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + SA D + P+ ++ A V++TSGSTG PKGV + + + NRL W
Sbjct: 1899 TL--DVSGFSAGPVGDGDRSGPVRPENPAYVIFTSGSTGRPKGVAVPHEGVVNRLLWMQD 1956
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + S+++ + KT +TF SV E++ PL+ G L+I + RDP L + R V
Sbjct: 1957 RYGLA-SDDVVLQKTPVTFDVSVWELFWPLIVGARLVIAEPDGHRDPAYLERVIREESVT 2015
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T+ + S+L G L SGE L A+ G E L N YG
Sbjct: 2016 TVHFVPSMLEVFLAGANVEGCGALHRVFTSGEALPSATAARLRGVSGAE----LHNLYGP 2071
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ + GSD+ +PIG P+ N Y+LD L GE+++ G L
Sbjct: 2072 TEAAVDVTFHEVSGSDRT----VVPIGAPVWNTQTYVLDGRLRVVPVGVAGELYLGGVQL 2127
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHR 374
A GY G A+RF NP T RLYRTGD L G + Y GRTD QVK+RG R
Sbjct: 2128 ARGYQGRADLTADRFVANPFGTG----RLYRTGDRVRWLPSGELEYLGRTDFQVKLRGQR 2183
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+L E+E L + V + VV+ G + G+V GA + + AL
Sbjct: 2184 VELGEIEAVLLRREDVAQAVVVLRGDGSSGEYLAGYVVPVAGAVVDERVVRESAAVALPG 2243
Query: 435 YMMPQVIEV-ESIPLLVNGKVDRQGL 459
+M+P V+ V +P+ VNGK+DR+ L
Sbjct: 2244 FMVPSVVVVLAELPVTVNGKLDRKAL 2269
Score = 195 bits (476), Expect = 3e-48
Identities = 143/450 (31%), Positives = 224/450 (49%), Gaps = 22/450 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA K GA Y+P++ + P R+ +L DA P V+ +AD F+ +GVP +
Sbjct: 2903 VVALLAVVKTGAGYLPVDVASPAERLAFVLGDARPECVL-TTTADAGTFRGAGVPVVVLD 2961
Query: 80 --ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E S+ D + PL DS+A V+YTSGSTG PKGV++S+ + L
Sbjct: 2962 DPETVTALQQFSSLPVTDDDRRTPLHLDSVAYVIYTSGSTGQPKGVQVSHRNVITLLANT 3021
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
F + ++ ++ +A F SV E+WG L HG L+++ T R P++ + + R
Sbjct: 3022 QTLFGFGPADVWTMFHSA-AFDFSVWEMWGALAHGGRLVLVDYFTARSPERFLELLRGET 3080
Query: 198 VPTLLRSILMYLALGPASR----PLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V + ++ + L A R P L+ + GE L ++ G + L N
Sbjct: 3081 VTVVNQTPTAFYQLAEADRLAGGPGLSLRYVIFGGEALEFGQLRRWYARRG-DAAPVLVN 3139
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE V++ + D ++ IGR L +Y+LD L P GE++V+
Sbjct: 3140 MYGITETTVHVSHLPIH-RDLVEEESASVIGRGLPGLRVYVLDGRLHPVPPGVVGEMYVS 3198
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
GA ++ GY+G + RF +P R+YR+GD G G + Y GR D QV++
Sbjct: 3199 GAQVSRGYLGRAALTSGRFVADPFTPG---ARMYRSGDLGRWNGHGQLEYLGRNDLQVQV 3255
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
+G+R++L EVE AL GV + VV G DR ++G+V + GA I
Sbjct: 3256 KGYRIELGEVEAALLACEGVAQSVVTARG-DR----LVGYVVPETGAAIDPAAIIDAAAV 3310
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +M+P V+ ++ +P VNGK+DR+ L
Sbjct: 3311 RLASHMVPAAVVVLDELPRTVNGKLDRKAL 3340
Score = 158 bits (383), Expect = 6e-37
Identities = 152/547 (27%), Positives = 242/547 (44%), Gaps = 42/547 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+I+++ A K GAA+VP++P++P RITH+L D+ +L + + + +
Sbjct: 4438 SILSVWAVAKTGAAFVPIDPNYPDERITHMLVDSGVTLGVTTTAHRDRLPGAAHWLVLDE 4497
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A E + DA+ P+T D+ A +YTSGSTG+PKGV +++ + N Q
Sbjct: 4498 PAFAIECAERAGAPVTDADRSGPVTLDTAAYAVYTSGSTGVPKGVVVTHRGLDNFALDQL 4557
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
F + + T +F SV E G A ++++ T ++L + V
Sbjct: 4558 ERFGATPQSRTLHFSTP-SFDGSVFEYLQAFGAG-ATMVIAAPTVFGGEELARLLADRRV 4615
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ +L PA L L V GE EL + + G +L N YG T
Sbjct: 4616 THAFITTAALASLDPAG--LVHLTDLVFGGEACPPELVARW------APGRRLYNAYGPT 4667
Query: 259 E--VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E +M +++ ++ G+ I IG P+ +LD L P PGE+++AGA
Sbjct: 4668 ETTIMSNISEPMVPGNP-------ITIGGPIRGVTELVLDPRLQPVPVGVPGELYLAGAG 4720
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG-AVLYAGRTDAQVKIRGH 373
LA GY A RF +P +P +R+YRTGD ++ Y GRTD QVK+RG
Sbjct: 4721 LARGYHRRPALTAERFVAHP--VRPG-ERMYRTGDIVRWTADRSIEYVGRTDFQVKVRGF 4777
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E++ L P V L + G+ ++ +V G + L L
Sbjct: 4778 RIELGEIDSTLMSEPDVGFAATLAHRGPAGDTLLVSYVVPASGRSLDPVVLTRHLADRLP 4837
Query: 434 HYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
+M+P I V E IPL GK+DR L + + D I+
Sbjct: 4838 SHMVPTSITVLERIPLTAVGKLDRAALPEPDLLSGTGHDRVPVGPIE------------D 4885
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD-RGYYVEISDFLGASTL 551
VLG A G +GF+++GGNSL++ + +LR G + D A T+
Sbjct: 4886 AVAVVFAEVLGLARVGA---DAGFFDIGGNSLSATRVMARLRALLGTDCGVRDLFEAPTV 4942
Query: 552 GEVLSKM 558
+ +++
Sbjct: 4943 AALAARI 4949
Score = 147 bits (357), Expect = 9e-34
Identities = 136/450 (30%), Positives = 208/450 (46%), Gaps = 31/450 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++++LA K+GAAYVP++P++P RI H+L D+ +L I SA S+ ++ +P+
Sbjct: 779 SVLSMLAVAKSGAAYVPVDPNYPAERIEHMLGDSGAALGI-TVSAVRSLLPDA-IPWLVL 836
Query: 79 --EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+E +H DAE PL ++ + V+YTSGSTG PKGV +++ + N
Sbjct: 837 DDDEFRTHCAAHPVSVVTDAERARPLRVENPSYVIYTSGSTGRPKGVVVTHGGLDNFAAE 896
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
Q F +++ I + T +F SV E + + A +++ T +L R +
Sbjct: 897 QRSRFGATETSRILHFSTP-SFDASVSE-YLHVFAAAATMVIVPPTVYGGAEL---SRFL 951
Query: 197 LVPTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + ALG L L V GE EL + G +L+N Y
Sbjct: 952 KSERVTHGFVTTAALGTVEPDGLADLGDVVFGGEACPPELVERW------APGRRLSNAY 1005
Query: 256 GSTE--VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
G +E VM ++ S + TI +G PL +LD L P GE++VA
Sbjct: 1006 GPSEATVMSNI-------SAPMSPTGTITVGGPLRGFHEVVLDARLQPVPPGVAGELYVA 1058
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKI 370
G LA GY G A RF NP E R+YRTGD L Y GR D QVKI
Sbjct: 1059 GDGLARGYHGKSALTAERFVANPFGGPGE--RMYRTGDVVRWRTDLSLEYLGRIDFQVKI 1116
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++ E++ L P V + + G+ ++ +V G + + + +
Sbjct: 1117 RGFRIEPGEIDTVLHAHPRVRTAMTMPRTAPSGDTVLVSYVLPAAGHQLATRELIDYAAE 1176
Query: 431 ALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
L YM+P I V + IP+ GK+DR L
Sbjct: 1177 QLPTYMVPAAIVVLDEIPMTPVGKLDRAAL 1206
Score = 122 bits (294), Expect = 4e-26
Identities = 116/446 (26%), Positives = 202/446 (45%), Gaps = 22/446 (4%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++++ + KAGAA+VP++P++P+ RI ++L D +L + S ++
Sbjct: 5496 SVVSIWSITKAGAAFVPVDPTYPRDRIDYMLIDCRAALGLTVRSRRSTLPDTVPWLILDD 5555
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E+ A +A++ S+ DA+ PL A ++YTSGSTG PKGV +++ + +
Sbjct: 5556 EDFATQASAVSSAPITDADRTNPLHLAHPAYLIYTSGSTGRPKGVTVTHRGMADFTAETH 5615
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ F + + + +F SV E+ A +++ +L ++ R V
Sbjct: 5616 QRFQVTHESRVSQLASP-SFDASVFELM-MAFSASARVVIVPPAIVGGSELADLFRREQV 5673
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ AL + L L++ GE E+ + + G L + YG T
Sbjct: 5674 THATITPTALAALD--NDGLDSLRVLDLVGEACPPEVVARW------APGRSLHSGYGPT 5725
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T SD + ++ IG P A +LDE L P PGE+++AG +A
Sbjct: 5726 E-----TTIQASVSDPMRPGESVNIGAPARGFAFLVLDERLQPVPVGVPGELYIAGPGMA 5780
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGA--VLYAGRTDAQVKIRGHR 374
GY + RF +P R+YRTGD + A + Y GR+D QVK+RG R
Sbjct: 5781 RGYHNRAALTSERFVACNFG-EPGC-RMYRTGDVVRWRESASALEYIGRSDFQVKVRGFR 5838
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E++ L + P V + + G+ + +V + G + L
Sbjct: 5839 IELGEIDAVLTRHPAVAFAATIGHIGPSGDTVLASYVRAQDGQEVQPAGLRTYASERLPA 5898
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGL 459
+M+P V+ ++ IP+ GK+DR+ L
Sbjct: 5899 HMVPSAVVVLDRIPMTPVGKLDRKAL 5924
>UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular
organisms|Rep: Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 5372
Score = 213 bits (520), Expect = 2e-53
Identities = 167/548 (30%), Positives = 264/548 (48%), Gaps = 38/548 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I L+ KAGA YVP++PS+P+ R+ ++L+D+ P +++ F ++ +P E
Sbjct: 1641 IAGLVGILKAGAGYVPLDPSYPEERLAYMLEDSAPKMLLTQRDLR-ERFAQAAMPVLLLE 1699
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF- 138
A+ A + P LA L + +A ++YTSGSTG PKGV + ++ + N + WQ
Sbjct: 1700 ADAR-AENAIDSAPTTNPQLAGLNAQHLAYLIYTSGSTGQPKGVAMPHAPLVNLMHWQIA 1758
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------I 192
+T + + + AL F + EI+ L G L ++ + D ++L I
Sbjct: 1759 QTVEHRRPRQRTLQFAALGFDVAFQEIFSTLCAGGELSLIHSDMRLDFRRLFQHICEQRI 1818
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
ERL + P + L + +P L+ + +GE L + +F + +L
Sbjct: 1819 ERLYM-PCIALQALAEAVVAEPEQPECLLQDVITAGEQL--RITEPMRHFFARLNDARLH 1875
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIP-IGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE VT LEG+ Q +PT+P IG+P+ N IYLLDE + P GE++
Sbjct: 1876 NHYGPTE-SHVVTAMTLEGNPQA--WPTLPSIGQPVANTRIYLLDEHMRPVPVGVAGELY 1932
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQ---RLYRTGDFGTLVK-GAVLYAGRTD 365
+ G +A GY+ A+RF +P AT+ + RLY+TGD G G ++Y GR D
Sbjct: 1933 IGGVCVARGYLNRDDLTADRFIADPFATREDGNPCARLYKTGDLGCWQDDGNIIYMGRND 1992
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHI 424
Q+KIRG R++L E+E L Q PG+ VL G ++ + + + G A A H+
Sbjct: 1993 DQIKIRGFRIELGEIEARLGQYPGLRDAAVLAREDVPGEKRLVAYFSVQAGQALPEADHM 2052
Query: 425 EGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXX 483
L++ L YM+P + +E +P+ NGK+DR+ L AE V D
Sbjct: 2053 RLHLQAVLPDYMIPAAYVHLEKLPVSPNGKLDRRAL--------PQPSAEAFVSRDYQAP 2104
Query: 484 XXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEIS 543
V +V R R + F+ELGG+SL ++ I ++R G ++
Sbjct: 2105 FGDTETMLAALWCEVLSV-ERVGR-----QDHFFELGGHSLLAVKLIERMRQVGLSADVR 2158
Query: 544 DFLGASTL 551
G TL
Sbjct: 2159 VLFGQPTL 2166
Score = 211 bits (515), Expect = 6e-53
Identities = 145/447 (32%), Positives = 230/447 (51%), Gaps = 19/447 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL K+GA YVP++P++P R+ + L D+ P ++ S P++ S VP +
Sbjct: 552 IIGLLGILKSGAGYVPLDPAYPLERLAYTLGDSAPVALLSQQSVQPAL-PVSDVPLIYLD 610
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ + DE ++ SD +A V+YTSGSTG+PKGV + + + RL+ +
Sbjct: 611 DVDLQ------DERACNPQVSVRPSD-LAYVIYTSGSTGLPKGVMVEHRNVA-RLFSATQ 662
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + +++ + F SV EIWG LLHG LLI+ + +R P+ N+ V
Sbjct: 663 DWFGFNEQDVWALFHSFAFDFSVWEIWGALLHGGRLLIVPQLVSRSPEDFYNLLCSAGVT 722
Query: 200 TLLRSILMYLALGPAS---RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L ++ + L A + L+ + GE L + ++ N +L N YG
Sbjct: 723 VLNQTPSAFRQLIAAQDDKEQVHSLRQVIFGGEALETAMLKPWYARKVNAST-QLVNMYG 781
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE VTYY L+ D + + PIG+ + + +YLLD P GE++V GA
Sbjct: 782 ITETTVHVTYYPLQPEDARRVGAS-PIGKRIPDLQLYLLDAYGHPLPPGAVGELYVGGAG 840
Query: 317 LAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ N RF D+P A+ P R+YR+GD G L G++ Y GR D QVKIRG
Sbjct: 841 VARGYLNRDELNTTRFLDDPFASAPG-ARMYRSGDLGRWLPDGSLEYLGRNDEQVKIRGF 899
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L+ GV VV+ + G+ ++ +V G A + +LR +L
Sbjct: 900 RIELGEIEARLSACEGVRDAVVVVREDEPGDQRLVAYVIGTAGQEPDATWLREQLRLSLA 959
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL 459
+M+P + +E+ PL NGK+DR+ L
Sbjct: 960 EHMLPSAFVSLEAFPLTANGKLDRKAL 986
Score = 190 bits (464), Expect = 9e-47
Identities = 138/445 (31%), Positives = 226/445 (50%), Gaps = 28/445 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG YVP++P++P RI ++L+D+ P+ V+ +A S+ + VP + +
Sbjct: 4859 VVGLLAILKAGGGYVPLDPAYPVDRIAYMLQDSAPAAVLAQ-TATQSLLADVSVPVINLD 4917
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + DE + + LTS +A ++YTSGSTG+PKGV + + N L W
Sbjct: 4918 QDSWQ------DESVQNPEVPGLTSVHLAYLIYTSGSTGLPKGVMIEHRNTVNFLTWAHS 4971
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F S E+ ++ T+L F +V E +GPL G ++ ++ + +I + VP
Sbjct: 4972 AFAGSALEK-TLFSTSLNFDLAVYECFGPLTSGGSIKVV-QNVLELQHGDHDIGLINTVP 5029
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ L+++L +L + + +GE L + L F+ G + +L N YG +E
Sbjct: 5030 SALKALLEINSLPKSVHTVN------VAGEALKRSLVENLFEKTGVQ---RLCNLYGPSE 5080
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
TY D+ + IG+P+ N YLLDE+ GE+++ GA +A
Sbjct: 5081 T---TTYSSWVAMDREQGFAP-HIGKPVGNTQFYLLDEQQQLVPLGVAGEIYIGGAGVAR 5136
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ A RF + + P+ R+YRTGD G L G + Y GR D QVKIRG R++
Sbjct: 5137 GYLNRDDLTAERFLADTFSRHPQ-ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIE 5195
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA-QHIEGKLRSALTHY 435
L E++ LA+ P V + VV G+ ++ + T A + G L L Y
Sbjct: 5196 LGEIDARLAKHPAVHEAVVTAREDVPGDKRLVAYYTVLSAQTEPAIDSLRGWLLGQLPAY 5255
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGL 459
M+P + ++++PL NGK+DR+ L
Sbjct: 5256 MVPVAYVRLDAMPLTPNGKLDRKAL 5280
Score = 176 bits (429), Expect = 2e-42
Identities = 160/564 (28%), Positives = 249/564 (44%), Gaps = 48/564 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T++A+LA KAGA YVP++PS P RI ++L D+ P +V+ A S E+ P +F
Sbjct: 3786 TLVAMLAVLKAGAGYVPVDPSHPDERIAYLLADSAPKVVL-TQQALTSRVPETAAPVIAF 3844
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + ++ +A L + +A V+YTSGSTG PKGV + + + N + W
Sbjct: 3845 DR-------PEWPQRLENPQVAGLNAAHLAYVIYTSGSTGQPKGVMVEHRTVGNLIDWHC 3897
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ F F E+W P L A L L + Q ++ +
Sbjct: 3898 QAFGLQAGSHTAS-VAGFGFDAMAWEVW-PALCAGATLHLPPADVGNEQIDALLDWWIAQ 3955
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
P + + +A SR L L TL + + + F + G+ + N YG T
Sbjct: 3956 PLQVAFLPTPVAEYAFSRNLSHPTL-----RTLL--IGGDRLRQFQRDPGFTVINNYGPT 4008
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E V+ S +L ++ IG+P+ N +YLLDE GE++VAG +A
Sbjct: 4009 EAT------VVATSGRLLPDGSLDIGKPITNTRVYLLDEHQQLVPLGVAGELYVAGEGVA 4062
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +P + R+YRTGD G + Y GR D QVKIRG RV
Sbjct: 4063 RGYLNRPEMTAERFLRDPFHCDAD-ARMYRTGDLARWNADGTLDYLGRNDDQVKIRGLRV 4121
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART-SAQHIEGKLRSALTH 434
+L E+E L+Q+PG+++ +VL + G P + + + G+ + + L + L
Sbjct: 4122 ELGEIEAQLSQLPGIEEALVLAREDEPGQPRLAAYFIERDGSLSMPVSELRAALLAVLPG 4181
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P + + + PL NGKVDR+ L D E D
Sbjct: 4182 YMVPSAFVRLAAWPLTANGKVDRRAL--------PLPDREALPGRDYEAPQGPVETAVAE 4233
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
++ V R R F+ELGG+SL ++ I ++R +G +I TL
Sbjct: 4234 IWSSLLQV-ERVGR-----HDHFFELGGHSLLAVNLIAQMRHQGLNADIRTLFTQPTLAA 4287
Query: 554 VLSKMSTDPNGGADSKEATFTAVP 577
+ + + GGA A+P
Sbjct: 4288 LAAAV-----GGASEITVPENAIP 4306
Score = 170 bits (413), Expect = 1e-40
Identities = 130/445 (29%), Positives = 217/445 (48%), Gaps = 32/445 (7%)
Query: 24 LATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELAQ 83
LA K A YVP++ + P R + +++D+ +++ + +G + L
Sbjct: 2742 LAVLKCAAVYVPLDVNAPVERQSFMIEDSRARVLLTHSQVSLT----TGAQRVDLDGLTL 2797
Query: 84 EATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPY 143
E + D L P +S+S+A ++YTSGSTG PKGV + + AI +RL +
Sbjct: 2798 ERLKGT-----DL-ALPPQSSESVAYIMYTSGSTGTPKGVLVPHRAI-SRLAINNGYADF 2850
Query: 144 SDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIERLVLVPT 200
+ + + + + F S ++W PLL+G ++++ + P Q+L+ +E+ V V
Sbjct: 2851 NAQDRVA-FASNPAFDASTLDVWAPLLNGGCVVVIGQHDLLSPLNFQRLL-LEQSVSVLW 2908
Query: 201 LLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEV 260
+ + A G RL+ + G+ L + + N L N YG TE
Sbjct: 2909 MTAGLFHQYASG-LGEAFSRLRYLIVGGDVLDPAVIG---RVLANNPPQHLLNGYGPTEA 2964
Query: 261 MG-DVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
TY ++ + +IPIG+P+ N +Y+LD + P GE+++ G +A
Sbjct: 2965 TTFSATYEIVSVGNG-----SIPIGKPVGNSRLYVLDNQGQPAPLGVGGELYIGGQGVAR 3019
Query: 320 GYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRVD 376
GY+ +F +P + P+ RLYRTGD G + Y GR D QVKIRG RV+
Sbjct: 3020 GYLHRDELTLEKFVADPFDSDPQ-ARLYRTGDLVRWRADGNLEYLGRNDEQVKIRGFRVE 3078
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT-KPGARTSAQHIEGKLRSALTHY 435
L E+E LA+ V + VVLC G+ ++ +VT +P +H+ L+ L Y
Sbjct: 3079 LGEIEARLAEHAEVREAVVLCRQDAPGDKRLVAYVTAQQPETALDIEHLRSHLQGLLPDY 3138
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGL 459
M+P ++++S+PL NGK+DR+ L
Sbjct: 3139 MVPAAYVQLDSLPLTANGKLDRKAL 3163
>UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6;
Bacteria|Rep: Nonribosomal peptide synthetase -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 4887
Score = 213 bits (520), Expect = 2e-53
Identities = 168/541 (31%), Positives = 257/541 (47%), Gaps = 38/541 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P +P RI ++L D+ P ++ D + P + +P +
Sbjct: 2703 VVGLLGILKAGGAYVPIDPGYPAERIAYMLDDSAPQALLADSATRP-LLGNLALPLVDLD 2761
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +P L LT +A V+YTSGSTG PKG + A+ NRL W
Sbjct: 2762 QPQWHR------QPRVNPRLNGLTPSHLAYVIYTSGSTGRPKGAMNEHRAVVNRLLWMQE 2815
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + +E+ + KT +F SV E + PL G L++ + +DP L + R +
Sbjct: 2816 QYRLT-AEDAVLQKTPFSFDVSVWEFFWPLFTGARLVMARPDGHKDPAYLRQVIRDERIS 2874
Query: 200 TL--LRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
TL + S+L ++LA G +R L+ +CSGE L L F + L N YG
Sbjct: 2875 TLHFVPSMLDVFLAYGD-TRECAGLRQVMCSGEALPGSLVRRFKQQLPQ---VALHNLYG 2930
Query: 257 STEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE DVT + G L P PIG+P+ N IYLLD ++ P GE+++ G
Sbjct: 2931 PTEAAVDVTAWDCAGP--LAQTPDNTPIGKPIANTRIYLLDAQMQPVPRGVVGELYIGGV 2988
Query: 316 NLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
+A GY+ A RF +P + +P RLYRTGD L G + Y GR D QVKIRG
Sbjct: 2989 QVARGYLNREQLSAERFLKDPFSQEPG-ARLYRTGDLARYLADGTIEYLGRNDDQVKIRG 3047
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA-QHIEGKLRSA 431
R++L E++ L Q+ GV + VVL G+ ++ + TT G A + + L
Sbjct: 3048 LRIELGEIQARLTQLEGVKEAVVLAREDVPGDQRLVAYYTTVAGQPALAVEQLRRALLEH 3107
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L +M+P + + + ++PL NGK++R+ L + E V
Sbjct: 3108 LPEFMVPALFMHLAALPLSPNGKLERKALPAPGLEAAQVREYEAPV------------GD 3155
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
+ A L + R + F+ELGG+SL ++ I ++R G ++ G T
Sbjct: 3156 TEILLAQLWAELLKVER--VGRHDHFFELGGHSLLAVSLIGRMRRAGLSADVRVLFGQPT 3213
Query: 551 L 551
L
Sbjct: 3214 L 3214
Score = 192 bits (467), Expect = 4e-47
Identities = 142/449 (31%), Positives = 216/449 (48%), Gaps = 35/449 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T++ LLA KAGA YVP++P+ P R+ ++L+D P V+ VP
Sbjct: 611 TVVGLLAILKAGACYVPIDPAHPAERLNYLLQDCGPRAVLTQAEL-LGRLPALAVPVI-- 667
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
EL Q D+ D + L++ ++A V+YTSGSTG+PKGV + + + N + W
Sbjct: 668 -ELNQRLW---LDQTADNTQVPGLSAANLAYVIYTSGSTGLPKGVMVEHRTLGNLVDWHC 723
Query: 139 RTFPYSD-SEEICVWKTALTFVDSVCEIWGPLLHGRAL-LILSRETTRDPQKLVNIERL- 195
+ F S+ C+ F E+W L G L L +++ + D L+ R
Sbjct: 724 QAFDLRPGSQASCL--AGFGFDAMAWEVWPALCVGATLHLAPAQDGSEDLDALLAWWRAQ 781
Query: 196 -VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ V L + Y P L+ + G+ L + F ++ G+ L N
Sbjct: 782 PLDVSFLPTPVAEYAFSQEQGHP--SLRTLLIGGDRL---------RQFSHDQGFALINN 830
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE + + +LD IGRP+ N IYLLD + P GE++V G
Sbjct: 831 YGPTEATVVASSGPIHAGGELD------IGRPVANARIYLLDSQQRPVPIGVAGELYVGG 884
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
A +A GY+ A RF D+P + QPE R+YR+GD L G + Y GR D QVKIR
Sbjct: 885 AGVARGYLNRPQLTAERFLDDPFSDQPE-ARMYRSGDLARWLADGRIDYLGRNDDQVKIR 943
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E L Q PG+ + V+L GNP ++ + T + + L +
Sbjct: 944 GVRIELGEIETRLCQFPGIQEAVLLAREDQPGNPRLVAYFTQQQDVALDVAQLRAHLLAQ 1003
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P + ++++PL NGK+DR+ L
Sbjct: 1004 LPDYMVPVAYVRLDALPLTANGKLDRKAL 1032
Score = 171 bits (417), Expect = 5e-41
Identities = 134/451 (29%), Positives = 213/451 (47%), Gaps = 41/451 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P P RI ++L+D+ P ++ S + G P +
Sbjct: 1656 VIGLLGILKAGGAYVPIDPGHPAERIAYLLQDSAPLALLVQGSTRALV----GQPAMARV 1711
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L Q + + + ++ +A V+YTSGSTG+PKGV + ++++ N L W +
Sbjct: 1712 DLDQPEWQARPEGNLQ---VPGMSCAHLAYVIYTSGSTGLPKGVMVEHASLENLLDWHCQ 1768
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETT--RDPQKLVNIER--- 194
F F E+W P L G A L L +D +L++ +
Sbjct: 1769 AFDLGPGRHASS-VAGFGFDAMAWELW-PTLCGGATLHLPPAGIGHQDLDQLLHWWQAQP 1826
Query: 195 --LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L +PT + LG + L+ + G+ L + F E + +
Sbjct: 1827 LDLSFLPTPVAEYAFSQGLGHPT-----LRTLLIGGDRL---------RQFSQEPSFAVV 1872
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE V+ S +L + IGRP+ N IYLLD + P GE++V
Sbjct: 1873 NNYGPTETT------VVASSGRLLAGGPLDIGRPIANARIYLLDPQQRPVPIGVAGELYV 1926
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
GA +A GY+ A RF ++P +T P R+YR+GD G + Y GR D QVK
Sbjct: 1927 GGAGVARGYLNRPELTAERFLEDPFSTVPG-ARMYRSGDLARWRADGRIDYLGRNDDQVK 1985
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++L E+E L ++PG+ + V+L G ++ + + PGA S + +L
Sbjct: 1986 VRGVRIELGEIETCLNRLPGIREAVLLAREDQPGQTRLVAYFSATPGAEPSPAELRRRLL 2045
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + + ++PL NGK+DR+ L
Sbjct: 2046 EQLPEYMVPAAYVHLAALPLTANGKLDRRAL 2076
Score = 165 bits (401), Expect = 4e-39
Identities = 133/452 (29%), Positives = 223/452 (49%), Gaps = 32/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDA-EPSLVIYDDSADPSMFKESGVPFASF 78
+++ LA K GAAYVP++ + P R+ +L D+ P L+ + + + + + F
Sbjct: 3788 LVSQLAVSKCGAAYVPLDVNAPAERLGFMLADSGAPVLLSHSERVLEAAVQRVDLDRLRF 3847
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ LA H+ + LA L+S+++A V+YTSGSTG PKGVR+ + AI RL
Sbjct: 3848 DRLA----GHNPN-------LA-LSSEAVAYVMYTSGSTGAPKGVRVPHRAI-TRLVIN- 3893
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVL 197
+ + E+ + + F S E+WGPLL+G ++++ T DP + +ER +
Sbjct: 3894 NGYADFNPEDRVAFASNPAFDASTLEVWGPLLNGGRVVVVDHATLLDPHAFGSLLERTGV 3953
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L + L + + + L++ +C GE A+ F + +L N YG
Sbjct: 3954 SLLFLTTSLFNQYVQLVPQAFKGLRMLLCGGERAD---ATAFRRIQAELPHLRLVNGYGP 4010
Query: 258 TEVMGDVTYYVLEGSDQLDL-YPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T+ V +L ++PIGRPL N +Y+LD P GE+++ G
Sbjct: 4011 TET---TTFAVTHEPGELAADADSVPIGRPLSNTRVYVLDALGQPLPVGVVGELYIGGDG 4067
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQR----LYRTGDFGTLVKGAVLYA-GRTDAQVK 369
+A GY+ A +F +P Q + +YRTGD G ++ +L GR D QVK
Sbjct: 4068 VALGYLNRPDLSAQKFLIDPFHQQTQGTAAPALMYRTGDLGRWLENGLLECIGRNDEQVK 4127
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT-KPGARTSAQHIEGKL 428
IRG R++ E++ LA+ PG+ V+ G+ ++ + T + A+ + L
Sbjct: 4128 IRGLRIEPGEIQAQLARFPGLRDGAVVVREDSPGDKRLVAYYTLHEHTPAPDAEQLRSHL 4187
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L YM+P + ++++PL NGK+DR+ L
Sbjct: 4188 QQQLPDYMVPLAYVHLQALPLTRNGKLDRRAL 4219
>UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase modules and
related protein; n=2; cellular organisms|Rep:
Non-ribosomal peptide synthetase modules and related
protein - Hahella chejuensis (strain KCTC 2396)
Length = 2853
Score = 213 bits (520), Expect = 2e-53
Identities = 161/464 (34%), Positives = 240/464 (51%), Gaps = 37/464 (7%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+AL A ++GAAY+P++ +P R+ +++++A P L+I S S F+ G F++
Sbjct: 2053 IALTAVLESGAAYLPLDTGYPDERLGYMVRNAAPRLII-TSSEQASRFRAMG-ELMLFDQ 2110
Query: 81 LAQEATSHSADEPMDAETLAP-LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L E E + + LAP LT D A ++YTSGSTG PKGV +S+ AI NRL W
Sbjct: 2111 LTAEVAQEYPQEQGE-DMLAPGLTPDHPAYLIYTSGSTGNPKGVLVSHGAIVNRLAWMQA 2169
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
+ ++++ + KT +F SV E + + G +L + E RDP +L+ IER
Sbjct: 2170 EYGL-QADDVVLQKTPCSFDVSVWEFFWAHMVGASLYMAPPEAHRDPDELLALIERHKVT 2228
Query: 195 -LVLVPTLLRSILMYLALGPASR---PLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
L VP++L + + L A P L+ CSGE L++ELA + Y
Sbjct: 2229 TLHFVPSMLAAFVNRLPAAIAELGEVPCAGLRRVFCSGEALTRELADLYSVYI----RAP 2284
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPT---IPIGRPLDNCAIYLLDEELSPTRDSEP 307
L N YG TE DVTY G + T +PIGRP+ N + +LD+ L P
Sbjct: 2285 LHNLYGPTEAAVDVTYKQASGPLDKERESTGLSVPIGRPVWNTQLRILDQWLRPAPVGVA 2344
Query: 308 GEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRT 364
GE+++ GA LA GY+G A RF + T+ E R+YRTGD L G V Y GR+
Sbjct: 2345 GELYLCGAQLADGYLGRPDLTAARFVAD---TEGEGARMYRTGDVARWLSNGDVEYLGRS 2401
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRG--------NPEILGFVTTKPG 416
D Q+KIRG R++L ++E AL +P V + VV ++ G N +++G+V
Sbjct: 2402 DDQLKIRGQRIELGDIESALQNLPDVKRAVVCARVINNGEAAMAGADNRQLVGYVIPH-A 2460
Query: 417 ARTSAQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
A + +L L +M+P ++ V PL NGK+DR+ L
Sbjct: 2461 DDIDADALRRRLAETLPAHMVPVAIVPVREFPLSANGKLDRKAL 2504
Score = 168 bits (409), Expect = 4e-40
Identities = 167/563 (29%), Positives = 253/563 (44%), Gaps = 61/563 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++LA AGAAY+P++ +P R+ +L+DA P L + ++A VP + +
Sbjct: 513 VVSILAVLSAGAAYLPLDLDYPPERLALMLEDARPKLALVHNAAAQDALAAI-VPCVALD 571
Query: 80 E--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR-LWW 136
+ L Q + S D E PL S +A V+YTSGSTG PKGV +++ ++ N L
Sbjct: 572 DPALTQRVNARSGAPVRDEERAEPLRSGHLAYVIYTSGSTGAPKGVMVTHGSLLNLVLSH 631
Query: 137 QFRTFPYS----DSEEICVWKTALTFVDSVCE--IWGPLLHGRALLILSRETTRDPQKLV 190
Q + + + +A D+ E IW LL G+ L I + E RD Q LV
Sbjct: 632 QASLYGAAMMQLHGRRVRAAHSASFSFDASWEQLIW--LLLGQELHICTEEQRRDAQGLV 689
Query: 191 NI--ERLV----LVPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYF 243
+ ER V + P++L+ +L L A P L + E L +Y
Sbjct: 690 ELAHERGVDAFDVPPSMLQQMLDCGLMREGAPHPC----LILIGSEAAPPSLWRRVKQY- 744
Query: 244 GNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTR 303
+ NFYG TE D + ++Q P + GRP+ N IY+LD+ L
Sbjct: 745 ---PKLHVHNFYGPTEYTVDALGAGVGAAEQ----PVV--GRPIANTRIYVLDQALRYAP 795
Query: 304 DSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLY 360
GE++VAGA LA GY+ G A RF +P + +YRTGD G + +
Sbjct: 796 QGVTGELYVAGAGLARGYLTRPGMTAARFVADPEG---QGDLMYRTGDLVRWTPDGQLEF 852
Query: 361 AGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS 420
GR+D QVK+RG RV+L EVE AL +PGV VV + + + T G R
Sbjct: 853 VGRSDRQVKVRGFRVELGEVEHALEALPGVSGAVVTA-ATAGASHRLTAYCTVNEGLRHD 911
Query: 421 AQHIEGKLRSALTH----YMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVA 475
+ + +L L+ YMMP + + + PL VNGK+D+Q L + + A V
Sbjct: 912 DEALRDRLYRQLSEMLPDYMMPSALAILPAWPLTVNGKIDKQALPTIRPPSRQTGKAPVT 971
Query: 476 VDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
+ + VLG + F+ LGG+S++++ T+LR
Sbjct: 972 AE-------------EKLVCAAIAQVLGLE---HTCVDDDFFNLGGDSISAMSLGTELRR 1015
Query: 536 RGYYVEISDFLGASTLGEVLSKM 558
GY + D T + M
Sbjct: 1016 SGYQLRPKDVFTQRTAARMSRAM 1038
>UniRef50_Q5DIU0 Cluster: PvdI; n=3; cellular organisms|Rep: PvdI -
Pseudomonas aeruginosa
Length = 3680
Score = 213 bits (519), Expect = 2e-53
Identities = 152/449 (33%), Positives = 228/449 (50%), Gaps = 32/449 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPF-ASF 78
++AL+ KAG AYVP++P +PQ R++++L+D+ L++ G+P A
Sbjct: 575 VIALMGILKAGGAYVPLDPEYPQERLSYMLEDSGVRLLL------TQAHLLDGLPVSAEV 628
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ L A S + ++ +T +++A V+YTSGSTG PKG +SA+ NRL W
Sbjct: 629 QPLVLAADSERLEGFDASDPEVAVTGENLAYVIYTSGSTGRPKGAGNRHSALTNRLCWMQ 688
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ S+ + + KT +F SV E + PL+ G L++ RDP +L+++ +
Sbjct: 689 DAYQLDGSDAV-MQKTPFSFDVSVWEFFWPLMVGARLVLAQPGDHRDPSRLMDLIGRESI 747
Query: 199 PTL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
TL + S+L P LK VCSGE L + + G +L N YG
Sbjct: 748 STLHFVPSMLQAFLQAPGVSACTSLKRIVCSGEALPVDAQQ---RVLAELPGVRLYNLYG 804
Query: 257 STEVMGDVTYYVL--EGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
TE DVT++ EG D T+PIGRP+ N Y+LD+ L P GE+++AG
Sbjct: 805 PTEAAIDVTHWDCREEGRD------TVPIGRPIANLRCYVLDDALEPVPVGALGELYLAG 858
Query: 315 ANLAAGY--VGGGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
A LA GY A RF +P AT +R+YRTGD G + YAGR D QVK+R
Sbjct: 859 AGLARGYHLRPALSAERFLADPFATG---ERMYRTGDLARYRADGVIEYAGRIDHQVKLR 915
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E L + V + VL +++G+VT + L +
Sbjct: 916 GLRIELGEIETRLLEHHAVREAAVLVV----DGKQLVGYVTLAAEPDEWRGMLSAHLAES 971
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P Q + +E +PL NGK+DR+ L
Sbjct: 972 LPEYMVPMQWVALERMPLSPNGKLDRKAL 1000
Score = 173 bits (422), Expect = 1e-41
Identities = 139/448 (31%), Positives = 214/448 (47%), Gaps = 22/448 (4%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILK-DAEPSLVIYDDSADPSMFKESGVPFASFEEL 81
++ T+KAGAAY+P++PS P+ R+ ++LK P+LV+ + + +P S L
Sbjct: 2074 MIGTFKAGAAYLPLDPSLPRSRLVNLLKLGGVPALVVGEGHQALARELLEELPEESRPAL 2133
Query: 82 AQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTF 141
A + + T+ +A V+YTSGSTG PKGV + + + N Q
Sbjct: 2134 LDWAAQQGQGKCEQRPGIVAPTN-GLAYVIYTSGSTGHPKGVMVEQAGMLNN---QLSKV 2189
Query: 142 PYS--DSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
P D ++ + +F SV + L G + IL + DP L ER +
Sbjct: 2190 PLLALDENDVIAQTASQSFDISVWQFLAAPLFGAQVDILPNDIAHDPLALSRRVRERGIT 2249
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V L+ S++ + P L L+ + +GE LS ELA + + L N YG
Sbjct: 2250 VLELVPSLIQEVLDDP-QETLPGLRWMLSTGEALSPELARRWLTRYPQVG---LMNAYGP 2305
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
E DV+++ ++ Y +PIG+ DN + +LD++L P GE++V+G +
Sbjct: 2306 AECSDDVSFFRVDTQSTGGTY--LPIGQATDNNHLQVLDDDLLPVPLGGIGELYVSGTGV 2363
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHR 374
GY+ G A F +P+A P R+YRTGD KG L Y GR D QVK+RG R
Sbjct: 2364 GRGYLADPGRTALAFLPDPYAQVPG-SRIYRTGDLACRGKGDQLEYVGRIDHQVKVRGFR 2422
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE--GKLRSAL 432
++L E+E L ++P V + VVL G V + A E L+ L
Sbjct: 2423 IELGEIESRLLELPIVREAVVLAQDGPTGKSLAAYLVPAESDTPLVALRDECRAALKGQL 2482
Query: 433 THYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + ++S+PL NGK+DR+ L
Sbjct: 2483 PEYMLPSLWRSLDSLPLNPNGKIDRKAL 2510
Score = 133 bits (321), Expect = 2e-29
Identities = 127/457 (27%), Positives = 209/457 (45%), Gaps = 36/457 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA KAG AYVP++ ++P R+ ++L+D +LV+ + + +P A
Sbjct: 3134 MVAFLAVLKAGGAYVPLDIAYPAERLRYMLEDCGAALVL----TQRDVLERLPLP-AGLA 3188
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA + D P A + L +++A V+YTSGSTG+PKGV +S+ + + + +
Sbjct: 3189 SLAVDGPGEWQDRPEGAPEV-DLAEENLAYVIYTSGSTGLPKGVAVSHGPLVSHI--RAT 3245
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRETTRDPQKLVNIERL--- 195
Y S C D E W PL++G +L+ + + R
Sbjct: 3246 GERYETSPADCELHFMSFAFDGAHEGWMHPLINGARVLVRDDSIWLPEETYAQMHRHGVT 3305
Query: 196 --VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V P L+ + + P+R ++ G+ + + AS + Y L N
Sbjct: 3306 IGVFPPVYLQQLAEHAERDGNPPPVR---VYCFGGDAVPQ--ASYELAWESLRPDY-LFN 3359
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + + D PIG L Y+L +L GE+++
Sbjct: 3360 GYGPTETVVTPLLWKARPQDPCGA-AYAPIGTLLGRRRAYVLGADLDLLPLGLAGELYLG 3418
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G +A GY+ A RF +P+ +R+YR+GD G V Y GR D QVKI
Sbjct: 3419 GEGVARGYLDRPALTAERFVPDPYGNG---ERVYRSGDLTRARADGLVDYLGRVDHQVKI 3475
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK-----PGARTSA--QH 423
RG R++L E+E L + V + VVL G +++G+V + G + A +
Sbjct: 3476 RGFRIELGEIEARLLEQECVREAVVLARDGANGK-QLVGYVVPQDVGALEGEKRGALREV 3534
Query: 424 IEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
++ L+++L YM+P Q + + ++PL NGK+DR+ L
Sbjct: 3535 LKSALKASLPEYMVPTQWVFLAALPLTPNGKLDRKAL 3571
>UniRef50_Q0LPK1 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1714
Score = 213 bits (519), Expect = 2e-53
Identities = 143/438 (32%), Positives = 226/438 (51%), Gaps = 22/438 (5%)
Query: 28 KAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELAQEATS 87
KAGAAY+P++P +P R +++ ++ LVI + P E + E + +
Sbjct: 94 KAGAAYLPIDPHYPYERQRFMIEHSQAPLVI---TTAPL---EGALASRPVEIQLELLMA 147
Query: 88 HSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSE 147
+A +P A + D +A V+YTSGS+G PKGV +++ A+ N + W TF ++ +
Sbjct: 148 IAAQKPTSAPNQR-VDPDQLAYVIYTSGSSGQPKGVMITHRALVNHMQWMQTTFGFNRHD 206
Query: 148 EICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERL-VLVPTLLRSI 205
+ KT L+F SV E + PLL G L++ + D LV I+R + V ++ S+
Sbjct: 207 RF-LQKTPLSFDASVWECYAPLLCGGQLILAKPDGHHDAHYLVEMIQRYQISVLQVVPSL 265
Query: 206 LMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMGDVT 265
L L P R L+ GE L EL ++ + ++ N YG TE D T
Sbjct: 266 LRMLQTEPQLANCRSLRYLFIGGEPLHSELVAQVRRVLPA----RMINLYGPTEATIDAT 321
Query: 266 YYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGY--VG 323
+ +Q YPTIPIG P+DN ++LD ++ P GE+++ G LA GY
Sbjct: 322 W---AECNQTTEYPTIPIGYPIDNLTTWVLDAQMQPVAVGRSGELYIGGMGLARGYQRQP 378
Query: 324 GGGANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVER 382
A RF +P +TQP RLY+TGD L GA+L+ R D Q+K+RG+R++L E++
Sbjct: 379 DRSAERFVPDPFSTQPG-TRLYKTGDRVRLLANGALLFLDRIDQQIKLRGYRIELGEIQA 437
Query: 383 ALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYMMPQV-I 441
L + P + + VV+ +++ +V P AR + + L++ L YM+P +
Sbjct: 438 GLERHPQIRQSVVVGQLDQTKTLQLVAYVVPMPEARIPIEQLRALLKAQLPRYMLPSAFV 497
Query: 442 EVESIPLLVNGKVDRQGL 459
+E +PLL NGK+DR L
Sbjct: 498 ILERLPLLANGKLDRASL 515
Score = 171 bits (416), Expect = 6e-41
Identities = 134/450 (29%), Positives = 214/450 (47%), Gaps = 36/450 (8%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
+TI +LA K GAAYVP++PS PQ R+ I+ +A+ ++ + + + S
Sbjct: 1153 ATIAGILAVLKLGAAYVPLDPSHPQQRLNLIINEAQLQAILVESQLEQLLPNTSAA---- 1208
Query: 78 FEELAQEATSHSA--DEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
+ + + H A D P+ A + + A L+TSGSTG PKGV S+ A+ N L
Sbjct: 1209 ---IIRLDSDHGAVTDYPIVA-------AQACAYGLFTSGSTGQPKGVACSHEAVINLLD 1258
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN---- 191
+ P +W T+L+F SV EI+ L G L ++ + D +
Sbjct: 1259 AMQQMRPLPQGCRHSLW-TSLSFDVSVYEIFSALTQGGTLYLIDQTMRLDADQFFAWLAK 1317
Query: 192 --IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
IE + P +L + ++L L+RL + V E + ++ + + G
Sbjct: 1318 YAIESAYIPPFMLHDLALWLMANRNRLQLKRLLVGV---EPIPEQNLAIIGQLI---PGL 1371
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
+ N YG TE T+Y + + D PIGR + A+Y+LD EL P G+
Sbjct: 1372 TIINGYGPTETTICATFYSVPPFN--DSARVTPIGRAIQQMAVYVLDRELQPMPTGVIGD 1429
Query: 310 VWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
+++AG LA GY+ A F NP + +P R+YR+GD G L G++++ GR+D
Sbjct: 1430 IYIAGIGLALGYIAKPDLTAEVFLPNPLSAEPGM-RMYRSGDRGRYLADGSLMFVGRSDR 1488
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVKIRG R++L E+ + Q V + VV Y NP+I+ +V G + +
Sbjct: 1489 QVKIRGMRIELNEIRTCVLQHAQVHEAVVNIYNDQPDNPQIVAYVVPTKGQLLTEASLRT 1548
Query: 427 KLRSALTHYMMPQV-IEVESIPLLVNGKVD 455
+ L M PQ + ++ +PL N K+D
Sbjct: 1549 YIGQKLPLAMQPQAFVLLDRLPLTANDKLD 1578
>UniRef50_Q2AZG3 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=16; Bacteria|Rep: Non-ribosomal peptide
synthase:Amino acid adenylation - Bacillus
weihenstephanensis KBAB4
Length = 4968
Score = 212 bits (518), Expect = 3e-53
Identities = 160/525 (30%), Positives = 262/525 (49%), Gaps = 41/525 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ L KAG AYVP++PS+P+ R+ +IL++++ +++ ++ + K+ +
Sbjct: 555 IIGLFGILKAGGAYVPLDPSYPENRLRYILENSQIQVLLTKEALQDWLPKD-------IQ 607
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + + ++ +T++++A ++YTSGSTG PKGV + + ++ NRL W +
Sbjct: 608 AICLDRDQVMISKESNLAPVSGVTANNLAYIIYTSGSTGNPKGVMIEHHSVINRLQWMQK 667
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
+P S+ E+ + KT +F SV E++ G + +L +DP + IER
Sbjct: 668 KYPLSE-EDTILQKTPFSFDVSVWELFWWSFVGARVCLLQPGGEKDPAVIEEYIERYRVT 726
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP++L + L Y+ + R L SGE L+ E F F + KL N
Sbjct: 727 TMHFVPSMLSTFLDYMEQYNSKRDESSLNQVFTSGEALNTEQVRRFKGVFYDVQQTKLIN 786
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE DVTYY + L+ P IPIGRP+DN +Y+LD+ GE+++
Sbjct: 787 LYGPTEATVDVTYYDCD----LEKEPMLIPIGRPIDNTELYVLDQYQQVVPIGVAGELYL 842
Query: 313 AGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIR 371
G LA GY PH + E +RLYRTGD + L Y GR D QVKIR
Sbjct: 843 GGVGLARGYFNRPELTTERFIPHPFK-EGERLYRTGDLVRYMNDRNLEYIGRIDNQVKIR 901
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E AL V + VVL G+ +++ +V G + + E L+
Sbjct: 902 GFRIELGEIEAALHDHSSVKEAVVLVKEDRPGDKQLVAYVV---GEGDTGEWRE-YLKKQ 957
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L +YM+P +VES+PL NGKVDR+ LL++ + D ++
Sbjct: 958 LPNYMVPAYFFQVESMPLTPNGKVDRKALLELEAQFISEDITSSRTPVE----------- 1006
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
VLG +S++ F+E+GG+SL + +++L++
Sbjct: 1007 -ELIVSVWSKVLGIR---NISVQDSFFEIGGHSLLATQVVSRLQE 1047
Score = 193 bits (470), Expect = 2e-47
Identities = 152/544 (27%), Positives = 253/544 (46%), Gaps = 39/544 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ L+ KAGAAYVP++PS+P+ R+ +IL+D +++ +++ + + +E +
Sbjct: 2659 IVGLMGILKAGAAYVPLDPSYPESRLRYILEDTGIQVLVTNEALEGWITEE-------IK 2711
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + +T +++A V+YTSGSTG PKGV + + + RL+
Sbjct: 2712 TVCLDRDKAMISRESTLSPICEVTGENLAYVIYTSGSTGNPKGVMVEHHNVI-RLFKSTE 2770
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP----QKLVNIERL 195
+ D ++ + F SV EIWG LLHG L+++ +R P Q LV +
Sbjct: 2771 CWYQFDEKDTWTLFHSYAFDFSVWEIWGALLHGGRLIVVPYWISRSPKDFYQLLVKEKVT 2830
Query: 196 VL--VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VL P+ R ++ + L L+ + GE L +F+ +G ++ +L N
Sbjct: 2831 VLNQTPSAFRQLIQVCEQEDEKKDL-HLRYVIFGGEALDPTSLVPWFQRYGGQEP-QLIN 2888
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTYY + D + IG+ + + +Y+LD P GE+++
Sbjct: 2889 MYGITETTVHVTYYPIT-QDDVQHASRSNIGKQIPDLEVYVLDACQQPVPIGVAGELFIG 2947
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA LA GY+ A RF +P ++ P RLYRTGD L G + Y GR D QVKI
Sbjct: 2948 GAGLARGYLNRSELTAERFIPHPFSSDPG-ARLYRTGDLARYLPDGNLDYLGRIDHQVKI 3006
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E AL + + VV+ G+ ++ +V +++ +L S
Sbjct: 3007 RGFRIELGEIESALNAHVSIKEAVVIVREDQPGDKRLVAYVVGDGNVGEWRDYLKAELPS 3066
Query: 431 ALTHYMMPQVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
H + + +E+IPL NGKVDR+ L E ++ +C
Sbjct: 3067 ---HMVPSGFVMMEAIPLTANGKVDRKALPVPEER---------KIESECVATRNGNEET 3114
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
VLG G + F+E+GG+S+ SI +++ + G + T
Sbjct: 3115 LATIWK---QVLGIKKVG---IHDNFFEIGGDSILSIQIVSRAKQAGLQLTPKQMFEHQT 3168
Query: 551 LGEV 554
+ E+
Sbjct: 3169 IAEL 3172
Score = 188 bits (457), Expect = 7e-46
Identities = 137/448 (30%), Positives = 218/448 (48%), Gaps = 29/448 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ L+ KAG+AYVP++PS+P+ + +IL+D +++ ++ + M +E E
Sbjct: 4182 IVGLMGILKAGSAYVPLDPSYPESHLRYILEDTGIQILVTNEVSQGWMPEE-------VE 4234
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW-QF 138
+ + + + +T +++A V+YTSGSTG PKGV + + ++ N + Q
Sbjct: 4235 TVCLDRDQAMISQENTLSPICKVTGENLAYVIYTSGSTGNPKGVMVQHHSVLNLSYGLQK 4294
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------I 192
F + + + V A DS + LL+G +L I+S E DPQ+ ++ +
Sbjct: 4295 EVFSHRAHDNMRVGLNASIAFDSSVKQLQMLLYGSSLYIISTEVRSDPQQFISYIRENKL 4354
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
E + P+LL+ +L+ L + + + GE + L + + D
Sbjct: 4355 EMFDITPSLLQ-LLIDEGLLETNDSVHVPSKVLVGGEAIMPSLWEQLVE----NDHIHFY 4409
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE D T Y ++ + + IGRPL N Y+LDE+L P GE+++
Sbjct: 4410 NVYGPTECTVDATCYRIKKDSK-----RVTIGRPLPNVQAYVLDEKLLPVPVGVTGELYI 4464
Query: 313 AGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
GA LA GY+ PH E +RLYRTGD L G + Y GR D QVKIR
Sbjct: 4465 GGAGLARGYLNRPELTLERFIPHPFN-EGERLYRTGDLVRYLADGHLDYLGRIDNQVKIR 4523
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E L P V + VVL G+ ++ +V + +H++ R
Sbjct: 4524 GFRIELGEIEANLESHPSVKEAVVLIREDQPGDQRLVAYVVGEGSMHEWREHLK---RQV 4580
Query: 432 LTHYMMPQVIEVESIPLLVNGKVDRQGL 459
H + IEV++IPL NGKVDR+ L
Sbjct: 4581 PNHMIPAHFIEVDAIPLTTNGKVDRKAL 4608
Score = 158 bits (384), Expect = 5e-37
Identities = 166/660 (25%), Positives = 299/660 (45%), Gaps = 77/660 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++LL KAG AYV ++P +P+ R+ ++++DA V+ + + +F++ V E
Sbjct: 1617 MVSLLGILKAGGAYVVLDPLYPKSRLEYMIEDAGIQFVVTAEGQE-GLFEQ--VEMVRLE 1673
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL E+ + + +++A ++YTSGSTG PKGV + Y ++ N + W
Sbjct: 1674 ELTVESVIAPTRQ---------INPENLAYIVYTSGSTGKPKGVMIEYRSLMNMVSWHHE 1724
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLV- 196
+ + +E+ + F +V EIW L G AL + + E +P+ L + I+ +
Sbjct: 1725 VYRIT-AEDRATQIAGIAFDSAVQEIWPYLTAGAALYLSTEELRINPEALRDWLIDSRIT 1783
Query: 197 --LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
PT + L+ L+ P LR + + G+ L++ Y N+ + + N
Sbjct: 1784 ASFAPTPILERLLKLSW-PDKTDLRFI---ITGGDQLTQ--------YPSNDIPFAVINQ 1831
Query: 255 YGSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG +E + YV G T IGRP+ N +Y+LD L G++++
Sbjct: 1832 YGPSENTVVTTDCYVPVGVTT----GTPSIGRPIANTEVYVLDSHLQLVPSGVIGDLYIG 1887
Query: 314 GANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +LA GY + F +P + +RLY TGD + L GA+ + GR D QVKI
Sbjct: 1888 GKSLARGYANRPDLTKEKFISHPFKSG---ERLYYTGDKASYLSDGALQFHGRIDDQVKI 1944
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L V + VVL D G+ ++ +V + + +H L++
Sbjct: 1945 RGFRIELGEIEAVLQAHSSVKEAVVLVREDDPGDKRLVAYVVGEGSVQEWREH----LQT 2000
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL-LKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
L +YM+P IE+E +PL NGK+D + L + +T N A ++
Sbjct: 2001 HLPNYMVPTNFIEMEFLPLTPNGKLDLKALPIPSKLSTENTVHARTPLE----------- 2049
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD-RGYYVEISDFLG 547
VLG + ++ F+ELGG+SL + +++L++ + + +
Sbjct: 2050 ---ELIASVWSQVLGIE---NIGVQDSFFELGGHSLLATQVVSRLQEVFQIKLPVRELFE 2103
Query: 548 ASTLGEVLSKMSTDPNGGADSKE-------ATFTAVPMRDEHKKEVIDMVESSFYEKAEL 600
ST+ E L+K G +E A+P+ + ++ + ++ A
Sbjct: 2104 YSTV-EALAKRLDQLRKGGKKREIPPLMPMERGNAIPL--SYAQQRLWFIDQFTPNSALY 2160
Query: 601 EQFLKHEIETRDYADCIDACWPALLQ--AGLSVVLNDVNSEPVAVALNFDVRDEPEIELS 658
+ + + ++ W L++ L V ++V+ PV + R P+I+L+
Sbjct: 2161 NMPMVCRLTGNWLLEALEVGWNQLIERHESLRTVFHEVDGHPVQKIQPYTFRSLPQIDLT 2220
>UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyketide
synthase; n=27; root|Rep: Non-ribosomal peptide
synthetase/polyketide synthase - Myxococcus xanthus
(strain DK 1622)
Length = 14274
Score = 212 bits (518), Expect = 3e-53
Identities = 166/559 (29%), Positives = 261/559 (46%), Gaps = 35/559 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL KAGAAYVP++P++P+ R+ +L+D S+++ + ++ S +
Sbjct: 9226 VVALLGVLKAGAAYVPVDPAYPKERLGWMLEDTGASVLLTHEKWK-TVLPPSAARVVCLD 9284
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A E +P A + P ++A V++TSGSTG PKG ++ + NRL W
Sbjct: 9285 SAAGEVAKQPVTKP--AVQVGP---QALAYVIFTSGSTGRPKGAMNAHGGVVNRLKWMQE 9339
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ ++ + + KT +F SV E + PLL G L++ ++P LV + + V
Sbjct: 9340 EYGLGGTD-VVLQKTPFSFDVSVWEFFWPLLAGAKLVVARPGGHQEPAYLVKLMKAEGVT 9398
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T+ + S+L P L L+ VCSGE LS EL + + G + N YG
Sbjct: 9399 TVHFVPSMLRAFVEEPGLEGLGSLRRVVCSGEALSAELVKKAYARLPAPVG--VHNLYGP 9456
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVTY+ + + +PIGRP+ N +Y+LD P PGE+ + G +
Sbjct: 9457 TEAAVDVTYWPCPRGED---FHRVPIGRPVANTVLYVLDTHGQPAPVGIPGELHIGGVQV 9513
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
GY A RF + + P RLYRTGD L G + Y GR D QVK+RG R
Sbjct: 9514 GRGYWQRPQLTAERFIPDAFSGIPG-ARLYRTGDVARWLPDGTLEYLGRADFQVKLRGFR 9572
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E AL PGV V + RG+ ++ +V T A A+ + +L L
Sbjct: 9573 IELGEIETALRMHPGVRDAVAVVREETRGDARLVAYV-TGDSAPLEAETLRAQLLKQLPQ 9631
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+M+P + + +PL +GKVDR+ L A A +
Sbjct: 9632 HMVPSTFVHLGVLPLTPSGKVDRKAL-----------PAPEAPTVQRGLYVAPRTPTEEA 9680
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
VL + G + + GF+ELGG+SL + + ++R R G + + F + T+
Sbjct: 9681 LAELFAQVL---SVGRVGIHDGFFELGGHSLLATQVVVRVRTRFGIELPLRAFFESPTVA 9737
Query: 553 EVLSKMSTDPNGGADSKEA 571
+ + + N A S A
Sbjct: 9738 GLAAYLDGQKNAPAQSDAA 9756
Score = 202 bits (493), Expect = 3e-50
Identities = 149/447 (33%), Positives = 226/447 (50%), Gaps = 23/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL KAGAAYVP++P++P+ R+ +L+D S+++ + +K P A+
Sbjct: 4811 VVALLGVLKAGAAYVPVDPAYPKERLGWMLEDTGASVLLTHEK-----WKSVLPPSAARV 4865
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A A +P+ ++ + ++A V++TSGSTG PKG ++ + NRL W
Sbjct: 4866 VCLDSAAGEVAKQPVTKPSV-QVGPQALAYVIFTSGSTGRPKGAMNAHGGVVNRLKWMQE 4924
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ S + ++ + KT +F SV E + PLL G L++ ++P LV + + V
Sbjct: 4925 EYGLSGT-DVVLQKTPFSFDVSVWEFFWPLLAGAKLVVARPGGHQEPAYLVKLMKAEGVT 4983
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T+ + S+L P L L+ VCSGE LS EL + + G + N YG
Sbjct: 4984 TVHFVPSMLRAFVEEPGLEGLGSLRRVVCSGEALSAELVKKAYARLPAPVG--VHNLYGP 5041
Query: 258 TEVMGDVTYYVL-EGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DVTY+ G D + +PIGRP+ N +Y+LD P PGE+ + G
Sbjct: 5042 TEAAVDVTYWPCPRGED----FHRVPIGRPVANTVLYVLDVHGQPAPVGIPGELHIGGVQ 5097
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+ GY A RF + + P RLYRTGD L G + Y GR D QVK+RG
Sbjct: 5098 VGRGYWQRPQLTAERFIPDAFSGIPG-ARLYRTGDVARWLADGTLEYLGRADFQVKLRGF 5156
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L EVE AL V V + G+ ++ +VT +P +A + +L L
Sbjct: 5157 RIELGEVEAALRAHLDVFDAVAVVREDAPGDQRLVAYVTGEPALDVAA--LRARLVEQLP 5214
Query: 434 HYMMPQVIE-VESIPLLVNGKVDRQGL 459
+M+P IE + S+PL NGKVDR+ L
Sbjct: 5215 AHMVPTAIETLPSLPLSPNGKVDRKAL 5241
Score = 186 bits (453), Expect = 2e-45
Identities = 134/411 (32%), Positives = 204/411 (49%), Gaps = 20/411 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL KAGAAYVP++P++P+ R+ +L+D S+++ + ++ S +
Sbjct: 1220 VVALLGVLKAGAAYVPVDPAYPKERLGWMLEDTGASVLLTHEKWK-TVLPPSAARVVCLD 1278
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A E +P A + P ++A V++TSGSTG PKG ++ + NRL W
Sbjct: 1279 SAAGEVAKQPVTKP--AVQVGP---QALAYVIFTSGSTGRPKGAMNAHEGVVNRLKWMQE 1333
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ S ++ + + KT +F SV E + PLL G L++ ++P LV + + V
Sbjct: 1334 EYGLSGTD-VVLQKTPFSFDVSVWEFFWPLLAGAKLVVARPGGHQEPAYLVKLMKAEGVT 1392
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T+ + S+L P L L+ VCSGE LS EL + Y ++ N YG
Sbjct: 1393 TVHFVPSMLRAFVEEPGLEGLGSLRRVVCSGEALSAELVKK--AYARLPAPVRVHNLYGP 1450
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVTY+ + + +PIGRP+ N +Y+LD P PGE+ + G +
Sbjct: 1451 TEAAVDVTYWPCPRGED---FHRVPIGRPVANTVLYVLDVHGQPAPVGIPGELHIGGVQV 1507
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
GY A RF + + P RLYRTGD L G + Y GR D QVK+RG R
Sbjct: 1508 GRGYWQRPQLTAERFIPDAFSGIPG-ARLYRTGDVARWLPDGTLEYLGRADFQVKLRGFR 1566
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
++L E+E ALA P V VVL G+ ++ +V A +AQ ++
Sbjct: 1567 IELGEIEAALAADPAVHDSVVLAREDSTGDQRLVAYVVLDDAA--AAQEVD 1615
Score = 183 bits (445), Expect = 2e-44
Identities = 165/554 (29%), Positives = 244/554 (44%), Gaps = 43/554 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAG YVP++PS+P R+ H+ A S V+ S PS+ K+ + +
Sbjct: 2697 VIGVLGALKAGGCYVPLDPSWPMKRLEHVSSAARLSAVLTWQSLLPSL-KDGPWHVVALD 2755
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + S + P+ D++A +TSGSTG PKGV + + + RL R
Sbjct: 2756 ADAADIARQSTEA-----VPVPVLPDALAFATFTSGSTGTPKGVAIPHRGLL-RLSEGTR 2809
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTR-DPQKLVNIERLVLV 198
F EE+ + + L F S E+WG LLHG L++ T D + IE V
Sbjct: 2810 -FLTQSPEEVTLQLSPLAFDVSSVELWGTLLHGGRLVVYPPGTPELDAVARLIIEHKVSW 2868
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
LL + L L L R+ + GE L E G L N YG T
Sbjct: 2869 -LLLPTSLFGLMQQHQPEALLRVPNLMVGGEALPAPRLRERLA-----QGGALTNAYGPT 2922
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E VT Y L D + L ++PIGRP+DN +Y+LD L P PGE+ + G LA
Sbjct: 2923 ECSTMVTRYTLSPGDTVGL--SVPIGRPIDNTEVYVLDPALCPVPVGVPGELCLGGPGLA 2980
Query: 319 AGYVGGGGANRFCDNPHA-TQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ C PH + RLYRTGD G + + GR D QVK+RG R++
Sbjct: 2981 RGYLNRPDLTAECFVPHPFSAVPGARLYRTGDRVRWRPDGVLEFLGRLDHQVKVRGFRIE 3040
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L E+E L P V + V+ G+ ++ +V + + L L YM
Sbjct: 3041 LGEIEAVLRAHPFVAEATVVVREDGSGSNRLVAYVVP---PQPDVAPLREYLHQHLPDYM 3097
Query: 437 MPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXX 495
+P I +++ PL GKVDR+ L +D +++
Sbjct: 3098 LPSAFIGLDAFPLTPTGKVDRKALPAPDLGLGASDFVAPRTELEQQL------------- 3144
Query: 496 XTVGAVLGRAARG--TLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
A L R A + L F+ LGG+SL + +T+LR R G + + F A T+
Sbjct: 3145 ----AALFREALDIERVGLNDDFFLLGGHSLLATQVVTRLRARLGVELPLRTFFEAPTVA 3200
Query: 553 EVLSKMSTDPNGGA 566
+ +++ + P GA
Sbjct: 3201 RLAARLESAPRTGA 3214
Score = 175 bits (427), Expect = 3e-42
Identities = 137/445 (30%), Positives = 208/445 (46%), Gaps = 25/445 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P +P R+ + +D+ + ++ + + + + + V +
Sbjct: 3755 LVGLLGILKAGCAYVPLDPEYPAQRLAFMAEDSGVAAILTEAALEDELPAGAQVVIVLDD 3814
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E S P+ + P D +A + YTSGSTG PKGV + + + RL R
Sbjct: 3815 EWTWIERQPST--PVTGGIVGP---DQLAYITYTSGSTGTPKGVAIPHRGVV-RLLIGSR 3868
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVLV 198
SE + + L F S EIWG LLHG A L+L + T D +L +ER +
Sbjct: 3869 FVDLGPSE-VVLQLAPLAFDASTLEIWGALLHG-ARLVLYPQRTLDLAELGQALERHHVS 3926
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L + L LR+++ + G+ L E G L N YG T
Sbjct: 3927 VLWLTAALFDQMQQHQPEALRKVRQLLAGGDVLPAPRVRERLA-----QGVGLVNGYGPT 3981
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + + D + ++ IGRP+ N +Y+LD + PGEV++ G LA
Sbjct: 3982 ESTTFTACHRMAAGDAVG--DSVSIGRPIANTQVYVLDPAMRAAPVGVPGEVFIGGDGLA 4039
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+G A RF NP P RLYR+GD L G + + GR D QVK+RG R+
Sbjct: 4040 RGYLGQPALTAERFVPNPFG--PPGARLYRSGDRARWLADGTLQFLGRVDFQVKLRGFRI 4097
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E AL V+ + L G+ ++ +VT + + LR L Y
Sbjct: 4098 ELGEIETALRSHSEVETAIALVREDSPGDRRLVAYVTPED---VDTASLREHLRQRLPEY 4154
Query: 436 MMPQ-VIEVESIPLLVNGKVDRQGL 459
M+P V+ + ++PL NGKVDR+ L
Sbjct: 4155 MVPNAVVVLSTLPLSPNGKVDRKAL 4179
Score = 174 bits (423), Expect = 9e-42
Identities = 174/601 (28%), Positives = 271/601 (45%), Gaps = 51/601 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA KAG A+VP++PS P R + +LKD++ S+++ + P ++ P
Sbjct: 13481 IVAVLAVLKAGGAFVPIDPSAPAQRKSFVLKDSDASVLL---TVQP--LADAWKPQVRHL 13535
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
S+ A P D T+ + +++A V+YTSGSTG PKGV + + ++ +
Sbjct: 13536 LCLDTGASNLASRPTDDVTV-EVRGENLAYVIYTSGSTGTPKGVMVQHHSLASLHVASNL 13594
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
F + A + D + L G L +L +T RDP+ ++ ++
Sbjct: 13595 AFHLGQAPGQRFSLNAPLYFDVSMDQLVHLADGHCLCLLPDDTRRDPEAMLAWLEQQRVD 13654
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L P L +L L A P R L C+GE + L S N + N
Sbjct: 13655 VLDCTPAQLTLLLQAGLLERAHVPSRIL----CAGEAMDPSLWSR----LANTERTTAFN 13706
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLD--EELSPTRDSEPGEVW 311
YG TE TY ++ S P IG+PL ++LD ++L+P GE++
Sbjct: 13707 AYGPTESTVYATYARVQHSPS----PVPVIGKPLAGTRAFVLDARQQLAPL--GTAGELY 13760
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
+AG LA GY+G G A RF +P A+ P +RLYRTGD G + Y GR D QV
Sbjct: 13761 LAGDGLARGYLGQPGLTAERFVPHPFASTPG-ERLYRTGDKARWRHDGTLEYLGRLDFQV 13819
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L E+E AL V VVL G+ ++ ++ G + + + L
Sbjct: 13820 KLRGFRIELGEIEAALRAHEAVQDAVVLAREDVPGDKRLVAYIV---GGSATVEALRQHL 13876
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
+ L YM+P + + ++PL +GKVDR+ L + +A VA
Sbjct: 13877 QQRLPEYMVPPAFVSLPALPLNPSGKVDRKALPSPTLADTRSQEAHVA----------PR 13926
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFL 546
T +LG +S+RS F+ELGG+SL ++ + LR+ G + +S
Sbjct: 13927 DGLELRLVRTWEQLLGVE---PISVRSSFFELGGHSLLAVRLVAALRESLGRPLPLSALF 13983
Query: 547 GASTLGEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMVESSFYEKAELEQFLKH 606
A T+ E L+ + + G S F A E + V + AEL + L
Sbjct: 13984 QAPTV-EQLAALLRREDAGPTSSLVPFDAGRSGTEVPFFCVHPVGGNVLAYAELARLLGP 14042
Query: 607 E 607
E
Sbjct: 14043 E 14043
Score = 173 bits (420), Expect = 2e-41
Identities = 136/447 (30%), Positives = 211/447 (47%), Gaps = 23/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM-FKESGVPFASF 78
++A+LA KAG A+VP++ S+P R+ +L+DA P L++ + + + G+P
Sbjct: 5879 VIAMLAVLKAGGAFVPLDASYPAQRLAIMLEDAPPHLLLASRANHAKLPLPDGGLPTLLL 5938
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
EEL E ++ + + +A V++TSGSTG PKGV + + + RL
Sbjct: 5939 EEL-------DLSEWPTTSPVSDVGPNHLAYVMFTSGSTGRPKGVAIPHRGVL-RLSHSE 5990
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLV 196
+ E V A +F SV E+W PLL+G +++ E ++ +ER
Sbjct: 5991 PFIRFGVRETGLVMAPA-SFDGSVMELWLPLLNGSGVVLYPPEAQASDLDTLSRVVERHG 6049
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ + L + S L++L+ G+ LS G + N YG
Sbjct: 6050 VTLIHFPAGLFSQVVEHRSDLLKKLRAINVVGDILSAPHTRRTL----TTTGVPVTNGYG 6105
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T Y + Q+ ++PIGRP+ N Y+LD +L PGE++V G
Sbjct: 6106 PTENSIISTSYTAYEASQVGA--SVPIGRPVSNTQAYVLDSQLQLVPVGVPGELYVGGEG 6163
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGH 373
L GYV A RF P ATQP RLYRTGD G + + GR D QVK+RG
Sbjct: 6164 LGRGYVSRPDLTAERFIPAPFATQPG-ARLYRTGDLVRWRPDGTLEFIGRIDNQVKVRGF 6222
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L +VE AL PGV + + G+ ++ + + A + +R L
Sbjct: 6223 RIELADVEAALRTQPGVLEAAAVVREDIPGDKRLVAYAMGRDDAPLDVAALRAGMRQRLP 6282
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P V + + ++PL +GKVDR+ L
Sbjct: 6283 EYMVPSVFVVLPTLPLSTSGKVDRKAL 6309
Score = 167 bits (407), Expect = 8e-40
Identities = 156/562 (27%), Positives = 253/562 (45%), Gaps = 45/562 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL KAG AYVP++ +P R+ +L+D+ +++ + + +G + E
Sbjct: 11351 LVALLGVLKAGGAYVPLDSEYPAERLRFMLEDSGARVIVARAAFRERLGAAAGCVWLDAE 11410
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
S+ P L P ++ A VLYTSGSTG PKGV + + ++ N +
Sbjct: 11411 ------VPPSSGVPQAPAVLVP--PEASAYVLYTSGSTGRPKGVVVQHQSLVNFTRAAWT 11462
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+FP + + + + ++++ S EI+ L G L++ + + +P + +
Sbjct: 11463 SFPVAPGDRVLQF-ASISWDTSAEEIYPCLTSGGTLVLRTPDMLDEPGAFLAKCGAAGVT 11521
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+L L + L G A P LK V GE ++ E +++ + G E L N
Sbjct: 11522 QLNLPTAFWHDVTASLDAGTARLP-PGLKWVVIGGERVAPERVAQWQRSVGVE--LPLLN 11578
Query: 254 FYGSTEVMGDVTYYVLEGSDQL---DLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
YG TEV T L + L +PIGR L N +Y+LD EL P PGE+
Sbjct: 11579 TYGLTEVTAVATSVNLSAAGVLASPGAEREVPIGRALTNVRMYVLDRELEPVPPGVPGEL 11638
Query: 311 WVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQ 367
++ G +A GY+G A RF +P + +RLYRTGD + G + Y GR D Q
Sbjct: 11639 FIGGWGVARGYLGRPELTAERFVPSPFV---DSERLYRTGDLARWRRDGNLEYLGRGDTQ 11695
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFV--TTKPGA-RTSAQHI 424
VK+RG R++ E+E AL P V VV G+ ++ +V ++ P A + A +
Sbjct: 11696 VKVRGVRIEPGEIEAALRAHPTVHDAVVHVREDVAGDKRLVAYVVPSSAPSAGQLEASAL 11755
Query: 425 EGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXX 483
LR L YM+P + + ++PL +GKVDR+ L A A +
Sbjct: 11756 REHLRGNLPEYMVPGAFVSLAALPLTPSGKVDRKAL-----------PAPEASQLALKRD 11804
Query: 484 XXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEI 542
V L R T+ F+ELGG+SL + + ++R D + +
Sbjct: 11805 SMPPATLMEARLAEVWQELLRVP--TVGRHDNFFELGGHSLLATRVVARVRADFNVELSL 11862
Query: 543 SDFLGASTLGEVLSKMSTDPNG 564
F A T+ + ++ + G
Sbjct: 11863 RAFFEAPTVAALAERLGSATPG 11884
Score = 153 bits (370), Expect = 2e-35
Identities = 148/554 (26%), Positives = 248/554 (44%), Gaps = 43/554 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I++LLA KAG A+VP++P P R + +L+D+ ++++ + +
Sbjct: 12422 IISLLAVLKAGGAFVPIDPMAPSQRRSFMLEDSGATVLLTVQHLAEAWRPQVRHVLCLDT 12481
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E A+ A+ + + P A + +++A ++YTSGSTG PKGV + + ++ L
Sbjct: 12482 EAARLASLPTYNVP------ANVRGENLAYIIYTSGSTGTPKGVMVQHRSLPWLLQGMTE 12535
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV---NIERLV 196
+ ++ + A + D E L G L ++ T +DP+ +V +R+
Sbjct: 12536 SLEMAEPAGQRLSLNAPLYFDGTVERLMHLAEGHCLCLVPEATRKDPEAMVAWLEQQRVD 12595
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
++ + + L G R +++ C GE +S L + + + N YG
Sbjct: 12596 MLDCTPAQLALLLQAGLLERSHVPARIF-CGGEAMSPML----WNRLASTERTTAFNVYG 12650
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T ++G+ P IGRP+ +Y+LD GE+ +AG
Sbjct: 12651 PTESTVCATSARVQGNPS----PVPVIGRPIVGTRVYVLDSRQQLAPLGTAGELCIAGEG 12706
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
+A GY G G A RF + + QP RLYRTGD G + Y GR D QVK+RG
Sbjct: 12707 VARGYFGRPGLTAERFIPDAFSGQPG-ARLYRTGDKARWRHDGTLEYLGRLDFQVKVRGF 12765
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E AL V VVL G+ ++ +V G +A+ + L L
Sbjct: 12766 RIELGEIEAALRTHGQVQDAVVLAREDVPGDKRLVAYVV---GDFITAESLRQHLLQRLP 12822
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P V + + ++PL GKVDR L D +++A+ D
Sbjct: 12823 EYMVPSVFVPLAALPLTSTGKVDRNAL-------PTPDASQLALTRDVEPPATPTEARLA 12875
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEIS--DFLGAST 550
+ + TL F+ELGG+SL + + ++RD + VE++ F A T
Sbjct: 12876 EIWKELLRI------PTLGRHDNFFELGGHSLLATQVVARIRDT-FDVELNLRAFFAAPT 12928
Query: 551 LGEVLSKM-STDPN 563
+ + ++ ST P+
Sbjct: 12929 VATLAERLASTTPS 12942
Score = 143 bits (346), Expect = 2e-32
Identities = 147/555 (26%), Positives = 239/555 (43%), Gaps = 39/555 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA KAG A+VP++P+ P R + +LKD S+++ ++ P
Sbjct: 10287 IVAVLAVLKAGGAFVPIDPAAPAQRKSFVLKDCNASVLL-----TLQHLADAWKPQVRNL 10341
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
S A P + + +++A V+YTSGSTG PKGV + + ++
Sbjct: 10342 LCLDTEASKLASLPT-RNAVVNVLGENLAYVIYTSGSTGTPKGVMVQHRSLLAMHAGTTE 10400
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL---VNIERLV 196
F + + + A D E L G L ++ ET +DP+ + V +R+
Sbjct: 10401 AFQATGATRQRISLNAPFHFDGALEPLVHLADGHCLCLVPEETRKDPEAMLAWVGQQRVD 10460
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
++ + + L G + ++ VC+GE ++ L +K + + N YG
Sbjct: 10461 VLDCTPAQLTLLLQAGLLEQTHVPSRI-VCAGEAMAPSL----WKQLASTERTTAFNAYG 10515
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T S + P IGRP+ Y+LD GE++++G
Sbjct: 10516 PTES----TVCATTASVRNSTAPVPVIGRPIQGTRAYVLDARQRVAPAGIAGELYLSGDG 10571
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY G A RF + + P RLYRTGD G + Y GR D QVK+RG
Sbjct: 10572 LARGYQGQPQLTAERFIPDAFSGTPG-ARLYRTGDKARWRHDGTLEYLGRLDFQVKLRGF 10630
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGF--VTTKPGARTSAQHIEGKLRSA 431
R++L E+E L V + VVL G+ ++ + V P A +A+ + +
Sbjct: 10631 RIELGEIEAVLRTHDQVQEAVVLVREDVPGDKRLVAYVVVVVTPEAPVTAELLRQHAQER 10690
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L YM+P + + ++PL GKVDR+ L D + +AV D
Sbjct: 10691 LPEYMVPSAFVLMGTLPLTPTGKVDRKAL-------PVPDVSNLAVKRDVE----PPATP 10739
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGAS 549
V L R T+ R F+ELGG+SL + + ++R + + F A
Sbjct: 10740 LEAQLAEVWKELLRVP--TVGRRDTFFELGGHSLLATQLVARIRATFDVDLNLRTFFAAP 10797
Query: 550 TLGEVLSKMSTDPNG 564
T+ + ++S+ +G
Sbjct: 10798 TVAALAERLSSASSG 10812
Score = 44.8 bits (101), Expect = 0.009
Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 11/159 (6%)
Query: 29 AGAAYVPMEPSFPQG------RITHILKDAEPSLVIYDDS--ADPSMFKESGVPFASFEE 80
AGA VP P P R+ I++DAE ++V+ + E F + +
Sbjct: 85 AGAVAVPAYPPDPVRLERTLPRLRAIIQDAEATVVLTTSGILSLADFVFEQAPDFRALKW 144
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
LA + + ++P D++A + YTSGSTG PKGV LS++ + + L
Sbjct: 145 LATDELPAGGESSWIEPQVSP---DTLAFLQYTSGSTGTPKGVMLSHANLIHNLGLIAGA 201
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILS 179
F +W + + I PL G + ++S
Sbjct: 202 FQTGPQSSGVIWLPPYHDMGLIGGILQPLFAGFPVTLMS 240
Score = 37.9 bits (84), Expect = 1.0
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 279 PTIPIGRPLDNCAIYLLDEELS-PTRDSEPGEVWVAGANLAAGY--VGGGGANRFCDNPH 335
P I G L + ++D E P + GE+WV+G ++A GY + F P
Sbjct: 371 PHIGCGSTLAEQRLLIVDPESRVPCAPGQVGEIWVSGGSVAQGYWRKPEDSVDIFQAVPV 430
Query: 336 ATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHRVDLLEVE 381
+ + RTGD G L++ G ++ GR + +RG + +VE
Sbjct: 431 GAEAG-PKYLRTGDLGLLLEDGQLIVTGRRKDLIILRGRNLYPQDVE 476
>UniRef50_O87314 Cluster: FxbC; n=5; Mycobacterium smegmatis|Rep: FxbC
- Mycobacterium smegmatis
Length = 4976
Score = 212 bits (518), Expect = 3e-53
Identities = 152/449 (33%), Positives = 223/449 (49%), Gaps = 33/449 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA KAG YVP++ P R+ HIL D+ P + + D+A+ + +GVP
Sbjct: 1638 IVAVLAVIKAGGTYVPIDIGAPAARVQHILADSAP-VCLLTDTAE----RFTGVPHVILA 1692
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E AQ P A T++P D A V+YTSGSTG+PKGV +++ +
Sbjct: 1693 EAAQNPA-----RPQ-APTVSP---DHAAYVIYTSGSTGVPKGVEVTHRNVAALFAGTTS 1743
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+++ + F SV E+WGPLLHG L+++ + RDP++ V++ V
Sbjct: 1744 GLYDFGPDDVWTMFHSAAFDFSVWELWGPLLHGGRLVVVEHDVARDPERFVDLLARERVT 1803
Query: 200 TLLRSILMYLALGPASRPLRR---LKLWVCSGETLSKELASEFFKYFGNEDGY--KLANF 254
L ++ + L A LRR L+ + GE L ++ N + + +L N
Sbjct: 1804 VLNQTPSAFYPLLEADARLRRQLALRYVIFGGEALD---VRRLAPWYANHESHSPRLVNM 1860
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE V++ L+ +D I G PL I+LLD L P GE+++AG
Sbjct: 1861 YGITETCVHVSHRALDTADTGAAGSVI--GGPLPGLRIHLLDNNLQPVPAGVVGEMYIAG 1918
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIR 371
+A GY G G A RF NP E RLYR+GD G ++Y GR+DAQVK+R
Sbjct: 1919 GQVARGYTGRPGLTATRFVANPFDGAGE--RLYRSGDLAMWTDAGELVYLGRSDAQVKVR 1976
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G+R++L EVE AL +PGV D G ++G+V G + L
Sbjct: 1977 GYRIELGEVEAALVTLPGVTNAAADVRHDDTGRARLIGYVV---GDALDIGALRSTLAER 2033
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P V + ++ +PL VNGK+DR L
Sbjct: 2034 LPDYMVPSVLLRLDVLPLTVNGKLDRAAL 2062
Score = 167 bits (407), Expect = 8e-40
Identities = 143/450 (31%), Positives = 220/450 (48%), Gaps = 55/450 (12%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL+A K+GAA++P++P +P+ R+ +++ DA P + + DD
Sbjct: 4216 VVALVAVAKSGAAFLPLDPEYPRERLEYMVSDARP-ITVLDDP----------------- 4257
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+A S EP D E L + + A VLYTSGSTG PKGV ++++ I NR+
Sbjct: 4258 ----DAVRRSRGEP-DGE-LPRIDPAAWAYVLYTSGSTGRPKGVAVAHAGIVNRIACLQH 4311
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+P + + V KT ++F SV E++ PL G L++ R+P L + E+ V
Sbjct: 4312 AYPLGTDDRMLV-KTPISFDTSVWEVFWPLSVGATLVVARPGGHREPAYLAAMIAEQCVT 4370
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L + L + L GE L+ ELA+ F + F G L N YG
Sbjct: 4371 AVDFVPSML-EVFLDEVAGTCASLTRVTVGGEALTTELAARFAEAF---PGVPLHNLYGP 4426
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DV + +G + +G P N Y+LD+ L+P PGE+++AG L
Sbjct: 4427 TEAAVDVLGWTADGG-------PVALGVPGWNVRAYVLDDYLNPVPAGAPGELYLAGIQL 4479
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHR 374
A GY+ G A RF +P + R+YRTGD G + Y GR+D Q+K+RG R
Sbjct: 4480 ADGYLHRGALTAARFVASPF---DQGARMYRTGDVVRWRADGQLEYLGRSDDQIKLRGVR 4536
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR----S 430
++ E+E LA P V V+ RG + +V G SA + +LR +
Sbjct: 4537 IEPGEIETVLATHPAVSSVRVIA----RGGRLMAYYVPA--GVEASAGELRDELREHAAA 4590
Query: 431 ALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
AL +M+P + + PL +GK+DR+ L
Sbjct: 4591 ALPSHMVPSGFVALTEFPLTPSGKLDRRAL 4620
Score = 154 bits (374), Expect = 8e-36
Identities = 164/582 (28%), Positives = 251/582 (43%), Gaps = 58/582 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL A +AGAAY+P+E +P R+ +L DAEP V+ + + + + P +
Sbjct: 3157 VVALFAVLRAGAAYLPLELDYPDERLAVMLGDAEPVRVLVTGATAQRIARVASAPLTVLD 3216
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + A D + +P D A V+YTSGSTG PKGV + + N + R
Sbjct: 3217 --APDTCDELARARSDWDGYSP-HPDQPAYVIYTSGSTGKPKGVVTPHRGLTN-MHLNHR 3272
Query: 140 ------TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-- 191
T + + + T D E L+ G + I RD LV
Sbjct: 3273 EAIFAPTIARAHGRRLKIAHTVSFSFDMSWEELLWLIQGHEVHICDEVLRRDATSLVRYC 3332
Query: 192 ----IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
I+ + + PT + L A P L + GE +S + + + +E
Sbjct: 3333 HDHRIDVINVTPTYAALLFEEGLLEQAGHPP---VLVLLGGEAVSTTVWN---RLRDSER 3386
Query: 248 GYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP 307
Y N YG TE T L G PT+ G P+ N ++LD L P D P
Sbjct: 3387 WYGY-NLYGPTEY----TINTLGGGTDDSATPTV--GTPIWNTRAHILDNWLRPVPDGVP 3439
Query: 308 GEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGA---VLYAG 362
GE+++AGA LA GY+G G A+RF NP E R+YRTGD +V+ A + + G
Sbjct: 3440 GELYIAGAGLARGYLGQPGLTASRFVANPF----EPGRMYRTGDL--VVRRADDNIDFLG 3493
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
RTD QVKIRG+RV+L ++E AL P + V+ G+ ++ +V
Sbjct: 3494 RTDDQVKIRGYRVELGDIEAALVSTPASHRPRVIARPDTAGSSRLVAYVVPTTENPDVLD 3553
Query: 423 HIEGKLRSALTHYMMPQVI-EVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCS 481
+ L + L YM+P + + IPL NGK+D + L +VA
Sbjct: 3554 DLRMHLTATLPAYMVPTAMATLTEIPLTDNGKLDTRAL------------PDVAPIGRHG 3601
Query: 482 XXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYV 540
VLG LS+ F++LGG+SL +I I+++R + G +
Sbjct: 3602 AGRAPQGAVEATLCSVFAEVLGLDGPDGLSVDDDFFDLGGHSLLTIRLISRIRSELGAEL 3661
Query: 541 EISDFLGASTLGEVLSKMSTDPNGGADSKEATFTAVPMRDEH 582
+ D + T+ + ++ D D++ A P R +H
Sbjct: 3662 TLGDVFNSRTVAALARHVTADE---GDNRRPRLVAGP-RPQH 3699
Score = 117 bits (281), Expect = 1e-24
Identities = 137/500 (27%), Positives = 202/500 (40%), Gaps = 59/500 (11%)
Query: 108 AIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYS-------DSEEICVWKTALTFVD 160
A ++YTSGSTG PKGV Y+ + N +++ R ++ +E++ + T D
Sbjct: 208 AYLIYTSGSTGRPKGVLTGYAGLTN-MYFNHREAIFAPTVARAGSAEQLRIAHTVSFSFD 266
Query: 161 SVCEIWGPLLHGRALLILSRETTRDPQKLV------NIERLVLVPTLLRSILMYLALGPA 214
E L+ G + + E RD LV I+ + + PT + G
Sbjct: 267 MSWEELFWLVEGHQVHVCDEELRRDAPALVAYCHRHRIDVINVTPTYAHHLF---DAGLL 323
Query: 215 SRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQ 274
L + GE + + S + + GY N YG TE T L G
Sbjct: 324 DDGAHTPPLVLLGGEAVGDGVWSALRDH-PDSAGY---NLYGPTEY----TINTLGGGTD 375
Query: 275 LDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGG--ANRFCD 332
PT+ G+P+ N Y+LD L P D GE+++AG LA GY G A
Sbjct: 376 DSDTPTV--GQPIWNTRGYILDAALRPVPDGAVGELYIAGTGLALGYHRRAGLTAATMVA 433
Query: 333 NPHATQPEFQRLYRTGDFGTLVKGAVL---YAGRTDAQVKIRGHRVDLLEVERALAQVPG 389
+P+ R+YRTGD G+ Y GR D QVKIRG+RV+L E+E L + G
Sbjct: 434 DPYVPGG---RMYRTGDLVRRRPGSAELLDYLGRVDDQVKIRGYRVELGEIESVLTRADG 490
Query: 390 VDKCVVLCYGLDRGNP--EILGFVTTKPGARTSAQHIEG---KLRSALTHYMMP-QVIEV 443
V +C V+ P + +V A I G L L YM+P + V
Sbjct: 491 VARCAVVARATGANPPVKTLAAYVIPDRWPAEDAAFITGLRDHLARVLPGYMVPTRYGIV 550
Query: 444 ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLG 503
+++PL +NGK+D L + T+ V +VLG
Sbjct: 551 DTLPLTINGKLDVAALPEPIAATS-------------GTGRTPRTDREATLLEIVASVLG 597
Query: 504 RAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEVLSKMST--D 561
G + F+ LGG+S++SI + R G + D T+ + + T
Sbjct: 598 IDGIG---VDDDFFTLGGDSISSISVCGRARKAGLNITPRDVFRRRTIAALAASADTTQT 654
Query: 562 PNGGADSKEATFTAVPMRDE 581
P G D+ TA PM E
Sbjct: 655 PESGPDTGTGAITATPMLAE 674
>UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep:
Peptide synthetase 2 - Bacillus subtilis
Length = 2560
Score = 211 bits (516), Expect = 5e-53
Identities = 164/612 (26%), Positives = 292/612 (47%), Gaps = 54/612 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +L+ KAG AY+P++P +P+ RI+ +L D+ L++ + + + +
Sbjct: 1564 IIGVLSILKAGGAYLPIDPEYPKERISFMLNDSGAKLLLTERGLNKPADYTGHILYID-- 1621
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E ++S P D + + +D A V+YTSG+TG PKGV + + + + L Q
Sbjct: 1622 ----ECENNSI--PADVN-IEEIVTDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNL 1674
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK---LVNIERLV 196
F ++ E++ + F SV E++G LL+G L+++S+ET RDPQ L+ ER+
Sbjct: 1675 PFEFNH-EDVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPQAFRLLLKKERVT 1733
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
++ + + ++ + GE L L + + + + D L N YG
Sbjct: 1734 VLNQTPTAFYGLMLEDQNHTDHLNIRYVIFGGEALQPGLLQSWNEKYPHTD---LINMYG 1790
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE VT+ L +D I GRPL +++D ++ PGE+++ G
Sbjct: 1791 ITETTVHVTFKKLSAADIAKNKSNI--GRPLSTLQAHVMDAHMNLQPTGVPGELYIGGEG 1848
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ A+RF NP+ RLYRTGD L G + Y GR D QVK+RGH
Sbjct: 1849 VARGYLNRDELTADRFVSNPYLPG---DRLYRTGDLAKRLSNGELEYLGRIDEQVKVRGH 1905
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E++ AL Q P + + V+ ++G I ++ K + I L++AL
Sbjct: 1906 RIELGEIQAALLQYPMIKEAAVITRADEQGQTAIYAYMVIKDQQAANISDIRTYLKNALP 1965
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
+M+P ++I+++SIP+ VNGK+D++ L + + DD +I+
Sbjct: 1966 DFMLPARMIQIDSIPVTVNGKLDQKALPEPEKQAYTADDISPRNEIE------------- 2012
Query: 493 XXXXTVGAVLGRAARGT--LSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
TV A + L + + F++LGG+S+ ++ +L+ RG+ + + T
Sbjct: 2013 ----TVMAEIWEELLNVDELGVSANFFKLGGDSIKALQVCARLKQRGFETTVREMFEHQT 2068
Query: 551 LGEVLSKMSTDPNG---GADSKEATFTAV-------PMRDEHKKEVIDMVESSFYEKAEL 600
LGE+ +++ D G E T+T + + H + + + + +++A L
Sbjct: 2069 LGELSARVRKDVRAIDQGPVEGEITWTPIQQWFFSQSLESHHFNQSVMIYRAERFDEAAL 2128
Query: 601 EQFLKHEIETRD 612
+ LK + D
Sbjct: 2129 RKVLKSLVTHHD 2140
Score = 180 bits (438), Expect = 1e-43
Identities = 138/457 (30%), Positives = 228/457 (49%), Gaps = 42/457 (9%)
Query: 22 ALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEEL 81
ALL WKAG AY+P++P FP R++ +LKD++ + ++ ++ S +P S+E
Sbjct: 535 ALLGIWKAGGAYMPLDPHFPAERLSFLLKDSQAAQLLIEEDLI------SLIP-PSYEGN 587
Query: 82 AQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTF 141
H+ +A + P +A ++YTSG+TG PKGV + + I N L W+ +
Sbjct: 588 TI-TIEHTESYQTEAPNMPP---GDLAYLIYTSGTTGRPKGVLVDHHGIANTLQWRREEY 643
Query: 142 PYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VNIERL 195
++ ++I + + F V ++ PLL G +L+ + + +D L + +
Sbjct: 644 SMTE-QDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIARYKVSHM 702
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
++VP+L R +L + A + L++ +GE ++ +L E + +LAN Y
Sbjct: 703 IIVPSLYRVLLEVMTADDA----KSLRIVTFAGEAVTPDLL-ELNQIIC--PSAELANEY 755
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLD-EELSPTRDSEPGEVWVAG 314
G TE V +L L+ I IG P+ N +++L ++ P GE+ ++G
Sbjct: 756 GPTE--NSVATTILR---HLNKKERITIGHPIRNTKVFVLHGNQMQPI--GAAGELCISG 808
Query: 315 ANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
A LA GY + F D+P E +RLYRTGD G L G + Y GR D QVKIR
Sbjct: 809 AGLARGYYKQQELTQKAFSDHPFL---EGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIR 865
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G+R++L E+E L Q PGV + VL + E++ ++ + G S + L
Sbjct: 866 GYRIELREIETVLRQAPGVKEAAVLARDVSAEEKELVAYIVPEKG--NSLPDLYQHLAGT 923
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTN 467
L YM+P +I + +PL +GK+DR L + NT+
Sbjct: 924 LPSYMIPASIINISQMPLTSSGKLDRFALPEPENNTS 960
>UniRef50_Q2SKF9 Cluster: Non-ribosomal peptide synthetase modules
and related protein; n=1; Hahella chejuensis KCTC
2396|Rep: Non-ribosomal peptide synthetase modules and
related protein - Hahella chejuensis (strain KCTC 2396)
Length = 1756
Score = 211 bits (515), Expect = 6e-53
Identities = 146/452 (32%), Positives = 236/452 (52%), Gaps = 34/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA +AG AY+P++P +P RI ++L+++ ++++ SG +
Sbjct: 329 MVAILAILRAGGAYLPIDPGYPANRIQYVLENSGANVILTHRHL--LQLDTSGYTVIDID 386
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E A A E +AET+ ++++A +YTSGSTG PKGV + + ++ NR+ W
Sbjct: 387 EKALGA------EHAEAETVGG--AENLAYAIYTSGSTGKPKGVLIEHHSVINRIAWMQN 438
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+P + E++ + KT ++F SV E++ G + +L R+P+K+V +
Sbjct: 439 AYPLT-VEDVILQKTPISFDVSVWELFWWFFTGSRVCMLEPGGEREPEKIVAAIEAHKVT 497
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP++L + L Y+ A L+ L+ SGE L+ A F K +G +L N
Sbjct: 498 TMHFVPSMLNAFLDYVESTQAVARLQSLRKVFTSGEALTLHQAERFKKLLHVANGTRLIN 557
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT+ +LD + IG P+DN I+++D++L PGE+ +A
Sbjct: 558 LYGPTEATVDVTHLDCTAKPELD---KVTIGSPIDNTQIHIVDKQLRRLPIGVPGELCIA 614
Query: 314 GANLAAGY--VGGGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY + A+RF NP +R YRTGD L G + Y GR D QVK+
Sbjct: 615 GVGLARGYHALPEVTADRFVANPENAS---ERWYRTGDLARWLGNGEIEYLGRLDHQVKV 671
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT--KPGARTSAQHIEGKL 428
RG R++L E++ L V V L + G +++ +VT +P T QH+ G++
Sbjct: 672 RGFRIELQEIDAVLRSHSAVRDAVTLVHRA-AGLDKLVAYVTANGEPEPETLRQHVAGQV 730
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ YM+P VI +E +PL NGK+DR+ L
Sbjct: 731 PA----YMVPDMVIVLEQMPLSPNGKLDRKAL 758
>UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 8871
Score = 211 bits (515), Expect = 6e-53
Identities = 163/549 (29%), Positives = 258/549 (46%), Gaps = 36/549 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+ A K+GAA + ++PS P RI +++ A +LV+ AD + +G+P A F+
Sbjct: 2904 LAAMYAVVKSGAAVLALDPSHPTDRIESLIQSASAALVVTTGDADVPV--PTGLPVARFD 2961
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ EA + D + A L D++A V+YTSGSTG PKGV +S++AI N+L W
Sbjct: 2962 DIDHEARDTAP--VTDVDRGASLHPDNLAYVVYTSGSTGAPKGVAVSHAAIANQLAWSQA 3019
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
P + + V K + F ++ E + L G L++L + D L + + +
Sbjct: 3020 QLPIHEHDRT-VQKAPIAFDVAIWECFAALCSGSVLVLLPPDRQFDLDYLSGLLDDMQIT 3078
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + S+L L+ + GE +S AS G +L N YG
Sbjct: 3079 VVEFVPSLLDVFVNDHRHSFPGSLRRVLTGGEAISARTASSVLA-----QGVRLGNMYGP 3133
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
E TY+ + + T+PIG P+ N +Y++D L P GE+++ GA L
Sbjct: 3134 AEAAVTATYHDVAAARAAT---TVPIGSPVWNTQVYVVDGRLHPVVPGVTGEMYLGGAQL 3190
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+G G A RF NP R+YRTGD G + Y GRTD QV++ G+R
Sbjct: 3191 ARGYLGRPGITAGRFVANPFGAPGS--RMYRTGDLARWNPDGQLDYHGRTDFQVQLHGYR 3248
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+ EVE AL + PG+ + VV+ G ++G+V PG + + + RS L
Sbjct: 3249 VEPGEVESALLRHPGIAQAVVVPRADRNGAHHLVGYVVPVPGIDVAEEELLDHTRSLLPS 3308
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+M+P VI + ++PL +GKVDR L + T + ++ S
Sbjct: 3309 HMVPSAVISLSTLPLTPHGKVDRNALPIVDFTTRAAEFRSAGTAVEES------------ 3356
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
V VLG + G + F+ LGG+S+ +I + + + G + D T+
Sbjct: 3357 LVTLVRDVLGLESVG---VDDSFFALGGDSIMAIQLVARAKTAGLALTPRDVFEYKTIAR 3413
Query: 554 VLSKMSTDP 562
+ +ST P
Sbjct: 3414 LARAISTRP 3422
Score = 182 bits (443), Expect = 3e-44
Identities = 159/553 (28%), Positives = 255/553 (46%), Gaps = 36/553 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA +AGA Y+ ++ P R+ + DA P ++ + + A
Sbjct: 5494 VVALLAAQQAGAGYLALDVGHPADRLDATMSDAAPVCLVSTTDHAARLRRNLPTVLADDA 5553
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ S D D E A LT D++A V+YTSGSTG PKGV +++ + L+ R
Sbjct: 5554 DTRAHLLDLSPDPITDPERRAALTPDAVAYVVYTSGSTGRPKGVVVTHRNLTT-LFDNTR 5612
Query: 140 T-FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
T F +++++ ++ +A F SV E+WG LLHG L+I+ T R P + +++ R V
Sbjct: 5613 TAFDFAETDVWTLFHSA-AFDFSVWELWGALLHGGRLVIVDTVTARAPDEFLSLLRRERV 5671
Query: 199 PTLLRSILMYLALGPASR--PLR-RLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
L ++ + L A R P L+ V GE L ++ + +L N Y
Sbjct: 5672 TVLCQTPTAFAQLATAERNQPTDLALRYVVFGGEALEHGHLVDWLDRHDHTRP-QLVNMY 5730
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE VT + L D ++ IGR + +Y+LD L P GE++VAG
Sbjct: 5731 GITETTVHVTRHPL--GDPRPAARSV-IGRAIPGLRVYVLDRRLHPVPTGVTGEMYVAGN 5787
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
+ GY+ G R+ +P R+YRTGD +G + + GR+DAQV++ G
Sbjct: 5788 QVTRGYLHRSGLTVTRYVADPAGRGG---RMYRTGDLARWNAQGQLEFLGRSDAQVQLHG 5844
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIE---GKL 428
+R++ EVE L + P V + V DRG ++G+V + G +T A I+ G
Sbjct: 5845 YRIEPGEVEATLVRHPDVAQAAVSVRPDDRGTERLIGYVVPVRDGEQTRAVDIDRVLGFA 5904
Query: 429 RSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
R+ L +M+P + V + +PL NGK+DR+ L D AE S
Sbjct: 5905 RTILAPHMVPATLVVLDRLPLTPNGKLDRRQL-------PAPDFAE-----RVSTGRAPV 5952
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
VLG ++S F+ LGG+S+ +I +++ + G +V D
Sbjct: 5953 TASELALAEIFAEVLGVP---SVSADESFFALGGDSIMAIQLVSRAHEDGVFVTPRDIFE 6009
Query: 548 ASTLGEVLSKMST 560
T+ + +T
Sbjct: 6010 HQTVAALAEVAAT 6022
Score = 136 bits (329), Expect = 2e-30
Identities = 125/458 (27%), Positives = 206/458 (44%), Gaps = 40/458 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+ A K+GAA++P++P +P+ RI H+L D+ +L + + V +
Sbjct: 770 VRAVWAVAKSGAAFLPVDPGYPEARIAHMLTDSGANLGVTVSRHRGDL--PGDVEWIELH 827
Query: 80 EL-AQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ A + TS P+ DA+ PL D A ++YTSGSTG+PKGV +++ I N + Q
Sbjct: 828 DRNADDTTSVRTSTPVGDADRPRPLRWDHPAYLIYTSGSTGVPKGVVVTHRGIANLIAAQ 887
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
+ + + + + +F S+ E+ + G ++I+ E + +ER++
Sbjct: 888 IKGLDVPPTGRVAQFASP-SFDASLFELLAAVGSGARVVIVPPEVVGGTE----LERVLT 942
Query: 198 VPTLLRSILMYLALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ ++L L R L +GE E+ S + G ++ N YG
Sbjct: 943 DYQVTHAVLTPTTLATLEPRGAPTLSHLTVAGEVCPPEVVSTW------APGPRVVNAYG 996
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPI--GRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
TE + + L P P+ G P + +LD+ L P GE+++AG
Sbjct: 997 PTEA-------TIMSTISAPLVPDEPVSLGAPACGFEVVVLDDRLHPVPPGTVGELYLAG 1049
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-------GTLVKGA--VLYAGR 363
LA GY G A RF P + R+YRTGD G A + Y GR
Sbjct: 1050 PGLARGYRNRAGLDAVRFVAAPFGSPG--TRMYRTGDLVRWRVRHGEDPSAALDLAYVGR 1107
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCV-VLCYGLDRGNPEILGFVTTKPGARTSAQ 422
+D QVK+RG R++L E+E L P V V + G+ ++ +V G R
Sbjct: 1108 SDFQVKVRGFRIELGEIEAVLRADPSVGFAVATAATDPNTGDAAVIAYVHPAEGRRVDVG 1167
Query: 423 HIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ +L L +M+P V+ ++ IP +GK+DR L
Sbjct: 1168 EMHRRLARTLPAHMLPAAVVPLDVIPRTPSGKLDRAAL 1205
Score = 135 bits (326), Expect = 5e-30
Identities = 129/446 (28%), Positives = 204/446 (45%), Gaps = 25/446 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+ A ++GAA VP++P++P RI H+L DA +L + + V + +
Sbjct: 8094 VRAVWAVARSGAASVPVDPTYPLTRIAHMLADAGAALGLTVAGYRAQL--PDTVEWLVLD 8151
Query: 80 ELAQEA-TSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ E T H P+ D + APL +D+ A ++YTSGSTG PKGV +S+ + N L+ Q
Sbjct: 8152 DPDFETQTRHFPSTPVTDVDRTAPLRTDNPAYLIYTSGSTGAPKGVVVSHRGLAN-LFEQ 8210
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
R + + + +F S+ E+ G A ++L T L +I +
Sbjct: 8211 ERHHLHVTPDARVSHLASPSFDASLFELTMAFCAG-AQVVLVPPPTYGGSALADILAVER 8269
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + L P L L++ V +GE +LA + G ++ + YG
Sbjct: 8270 ITHAFITPTALATLEPTG--LDSLRVLVVAGEPCPTDLARRW------APGRRMLDAYGP 8321
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + +V S+ L + IGRP+ +LD L P PGE+++AG L
Sbjct: 8322 TET--TIWSHV---SEPLAPAEPVTIGRPVRGFTAAVLDARLHPVPPGTPGELYLAGPGL 8376
Query: 318 AAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHR 374
A GY A F P A P + R+YRTGD L + GRTD Q+K+RG R
Sbjct: 8377 ARGYHDRPATTATHFVACPFAA-PGW-RMYRTGDLVRTRPDLTLEHLGRTDFQIKVRGFR 8434
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+ EV+ LA + + G P ++ +V G A + L + L
Sbjct: 8435 VEPGEVDSILAARADIGFAATVGRTGPDGEPILVTYVHGATGVDVDASAVRTALSAQLPP 8494
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL 459
Y++P V+ ++ +PL GK+DR L
Sbjct: 8495 YLVPAAVVVLDEVPLTPAGKLDRSAL 8520
Score = 132 bits (320), Expect = 3e-29
Identities = 132/454 (29%), Positives = 204/454 (44%), Gaps = 34/454 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFK-ESGVPFAS 77
+++A+ A K GAA+VP++P +P RIT ++ D+ +L + + P + + VP+
Sbjct: 7035 SVLAVWAITKTGAAFVPIDPGYPAARITDMIADSGVALGV---TLTPQRERLPATVPWLV 7091
Query: 78 FEE--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
+E + DA+ PL D A ++YTSGSTG+PKGV + + +
Sbjct: 7092 LDEPGTVTMVEQQPSGAVGDADRRRPLRPDHPAYMIYTSGSTGVPKGVVVPHRGLATLAA 7151
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
Q + + + +F SV + G A L++S T +L R
Sbjct: 7152 AQAAGLGPGRHSRVLHFSSP-SFDGSVFDYLLAFGCG-ATLVISPPTIVGGTEL---SRF 7206
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
V + + + AL AS L + GE L+ A G L N Y
Sbjct: 7207 VAAERVTHAFVPTAAL--ASADPDDLDGYDGFGEILAAGEACPPGLVTRWSRGRALRNGY 7264
Query: 256 GSTE--VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
G TE VM +++ + GSD + IG P+ +LD L P D PGE+++A
Sbjct: 7265 GPTETTVMSNISAPLAPGSD-------VTIGGPIAGAEEVVLDARLQPVPDGVPGELYIA 7317
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK----GAVL-YAGRTDA 366
G LA GY G A RF P+ P +R+YRTGD + G V+ Y GR D
Sbjct: 7318 GPGLARGYHRRPGLTAGRFVAAPYG--PAGERMYRTGDIVRWIADTSGGRVVEYLGRADF 7375
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVK+RG R++ EV+ L P V+ L G+P ++ +V A + +
Sbjct: 7376 QVKVRGFRIEPAEVDAVLGAHPDVEYAATLTRTGPAGDPILVSYVV--GSAELAPALLSA 7433
Query: 427 KLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
L L +M+P ++ ++ IPL GK+DR L
Sbjct: 7434 YLTERLPAHMVPSAIVPIDRIPLTPVGKLDRAEL 7467
Score = 113 bits (271), Expect = 2e-23
Identities = 126/455 (27%), Positives = 205/455 (45%), Gaps = 39/455 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+ A GAA+VP++P++PQ RI H++ D+ + + S ++ V +
Sbjct: 4433 SVLAVWAVAGTGAAFVPVDPTYPQIRIQHMVADSGVLVGLTTSSRRDAL--PDTVTWIDI 4490
Query: 79 EELAQEATSHSA-DEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E H+ E A T+ P D+ A ++YTSGSTG+PKGV + + + N L
Sbjct: 4491 EGTGAGRLPHAGVSEACPAPTIRP---DNAAYLIYTSGSTGVPKGVVVGHRGV-NSLATT 4546
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
R + + +F SV E G +I+ + ++ +
Sbjct: 4547 LRECTGVTAASRVAHFASPSFDASVLEYLLTWSAGATAVIVPTTIYGGDELRRHLADSRV 4606
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L + AL P L L+ V GE + E+ + + +L N YG
Sbjct: 4607 THAFLTPTTL-TALDPDG--LDDLECVVTGGEKCTPEVIRRWSPHC------RLINAYGP 4657
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + + SD IG P+ +LD + P GE+++AG +
Sbjct: 4658 TE-----STVAADISDDPAADGANVIGGPIRGVTEVVLDARMQPVPIRARGELYIAGDAI 4712
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD---FGTLVKG-AVL-YAGRTDAQVKI 370
A GY G A RF +P P R+YR+GD + T +G AVL Y GRTD+QVK+
Sbjct: 4713 ARGYHGKPALTATRFVADPFG--PPGGRMYRSGDVVRWNTGREGSAVLEYLGRTDSQVKV 4770
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVL--CYGLDRGNPE--ILGFVTT--KPGARTSAQHI 424
RG+R++ E++ L+ P V L G D + + ++ +VTT G R ++
Sbjct: 4771 RGYRIEPGEIDAVLSGHPAVTFSATLPSTGGPDTTDQDATLISYVTTAGAAGPRELRDYL 4830
Query: 425 EGKLRSALTHYMMPQVIEVESIPLLVNGKVDRQGL 459
G+L + L + VIE++ +P +GK+DR L
Sbjct: 4831 AGRLPAQL---VPSAVIEIDVVPRTPSGKLDRDAL 4862
Score = 85.0 bits (201), Expect = 7e-15
Identities = 109/461 (23%), Positives = 187/461 (40%), Gaps = 42/461 (9%)
Query: 12 PHFF-YFSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDD-SADPSMFK 69
PH Y + + +LA AG A +P++P + T P + I+ SA
Sbjct: 1839 PHSMDYVAVTLGVLA---AGGACLPLDPGWASPTQT---SRTIPDIAIFVTISAVEEHLP 1892
Query: 70 ESGVPFASFEELAQEAT-SHSADEPMDAETL-APLTSDSIAIVLYTSGSTGIPKGVRLSY 127
VP + A + + P+ A + A + D+ A VL T GST +PK V +++
Sbjct: 1893 HGHVPTLVLDAPGTVADLARRSGHPLTAVDVGAGPSPDTAAYVLLTRGSTALPKPVSVTH 1952
Query: 128 SAICNRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEI--WGPLLHGRALLILSRETTRD 185
A+ + L P + E VW TF V + W LHG L ++ T
Sbjct: 1953 RAVLSAL-----ARPAVPAGE--VWAMVPTFAPGVTVLTPWSAFLHGGRLEVVDDATASA 2005
Query: 186 PQKLVNI--ERLVLVPTLLRSILMYLALGPASRPLR-RLKLWVCSGETLSKEL--ASEFF 240
P L ++ R V + + +L+ S P L+ + +G+ + + A E
Sbjct: 2006 PSALADLLHRRGVNMVAQTPAAYEHLSRARESAPAADELRSVLLTGDPVDAAVVAAPEVV 2065
Query: 241 KYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELS 300
+ + + A +T+ + G+D+++ RP +LD+ L+
Sbjct: 2066 AVYASVEAVWFA---AATDRAPEA------GADRMEY-------RPARGRRFAVLDDRLA 2109
Query: 301 PTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVL 359
P GE+++ G LA GY A P +R+ RTGD L G +
Sbjct: 2110 PVPPGVVGELYIGGPTLARGYHRRAAATSTHFVASPLGPPGERMLRTGDAACLTPTGGLN 2169
Query: 360 YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART 419
R D Q ++RG+R+ L +++ L P V V + + G P ++ +V PG+ T
Sbjct: 2170 ILWRRDFQSELRGYRIPLGDIDTVLTAHPQVANAVTVDHTPRAGKPALVTYVVPAPGSTT 2229
Query: 420 SAQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ + L +P V+ ++ +P+ G VD L
Sbjct: 2230 TISEVRAHAAMILPPPWVPGAVVVLDRLPVTETGDVDLDAL 2270
>UniRef50_A1FGJ0 Cluster: Amino acid adenylation; n=2; cellular
organisms|Rep: Amino acid adenylation - Pseudomonas
putida W619
Length = 3404
Score = 211 bits (515), Expect = 6e-53
Identities = 183/613 (29%), Positives = 279/613 (45%), Gaps = 60/613 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AYVP++P +P+ R+ ++++D+ L++ + S+ GV + +
Sbjct: 575 VVALLAILKAGGAYVPLDPEYPEERLAYMIEDSGIGLLLTQQALLDSLPLPHGVQCVALD 634
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L D D+ + +A V+YTSGSTG PKG S+ A+ NRL W +
Sbjct: 635 TLV-------LDTMPDSTPGLKVEPTQLAYVIYTSGSTGRPKGAGNSHQALTNRLCWMQQ 687
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ D+ + + KT +F SV E + PL+ G L I + RDPQ+L+ V
Sbjct: 688 AYGL-DASDTVLQKTPFSFDVSVWEFFWPLMTGARLAIAAPGEHRDPQRLIRAIEHYRVT 746
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL + S+L P L VCSGE L + + F L N YG
Sbjct: 747 TLHFVPSMLQAFIHEPGVHACSTLSRIVCSGEALPVDAQRQ---VFARLPAAALYNLYGP 803
Query: 258 TEVMGDVTYY--VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE DVT++ V EG D ++PIG+P+ N Y+LD L P GE+++ G
Sbjct: 804 TEAAIDVTHWTCVEEGKD------SVPIGQPIANIRTYVLDAGLEPVAVGVAGELYLGGV 857
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRG 372
LA GY G A RF +P T +RLYRTGD G + Y GR D QVKIRG
Sbjct: 858 GLARGYHRRPGLTAERFVADPFGTG---ERLYRTGDRVRQRADGVIEYLGRFDHQVKIRG 914
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+E LA+ V +CVVL LD ++ ++ ++ L +L
Sbjct: 915 LRIELGEIEARLAEHALVRECVVL--ALD--GRRLVAYLVLNATPEGWQGQLKDWLLQSL 970
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
+M+P Q++ ++ +PL NGK+DR+ L + A
Sbjct: 971 PEFMVPSQLVPLDGLPLTPNGKLDRKALPQPEAGAQGTHVAP-------------QSAAE 1017
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
VLG A G L F+ELGG+S+ +I +++ R G + D TL
Sbjct: 1018 RQLAKVWCEVLGAAQVG---LDDNFFELGGDSIIAIQVVSRARQAGLALSPRDLFQHQTL 1074
Query: 552 GEVLSKMSTDPNGGADSK----EATFTAVPMR--------DEHKKEVIDMVESSFYEKAE 599
+ + + AD + EA T V ++ +H + + +V + A+
Sbjct: 1075 RALAQAAGSVDSCQADQRPAEGEARLTPVQLQFFDTPMPVRQHWNQAVLLVPREPLQAAQ 1134
Query: 600 LEQFLKHEIETRD 612
L+Q L + D
Sbjct: 1135 LQQALAQVVAQHD 1147
Score = 152 bits (369), Expect = 3e-35
Identities = 161/553 (29%), Positives = 247/553 (44%), Gaps = 49/553 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LLA KAGA YVP++ +P+ R+ +L D+ LV+ +A + +G A +
Sbjct: 2060 IVGLLAILKAGAGYVPLDSQYPRQRLQDMLDDSAVRLVLGTRTAAQPL-ALAGT--ADWL 2116
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L Q P D +D++ ++YTSGSTG PKGV L++ AI +
Sbjct: 2117 WLDQPLA------PQDDNPAPRACADNLLGLIYTSGSTGRPKGVALTHGAIAAHIATMVG 2170
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRETTRDPQKLVNIER---- 194
+ + +++ V ++ F D E W PL G ++ + Q IER
Sbjct: 2171 QYQVT-AQDRFVHFASINF-DWGTEQWLLPLSQGACCIVRGDDIWTAAQAFEVIERERAS 2228
Query: 195 LVLVPTLLRSILMYLALGPA-SRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+V PT L A + P+R + + +GE LS+E F + + ++ N
Sbjct: 2229 VVYFPTQYACQLAEWAHQQGRALPVRCMNV---AGEALSRE---GFERIQAHLQPQRIVN 2282
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + + +GS ++D PIG P+ YLLD L GE+++
Sbjct: 2283 GYGPTETVITPLLWQADGSTRIDT-GYAPIGTPVPGRTAYLLDTALQLLDTGTDGELYIG 2341
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKI 370
G LA GY G A RF +P+ T RLYR+GD G +++ GR D QVKI
Sbjct: 2342 GPCLARGYFGQAALTAERFVPDPYDTVGG-ARLYRSGDLVRQQANGELVFIGRLDHQVKI 2400
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA---QHIEGK 427
RG RV+ EVE L +P V + VV+ G + + ++ G++ A Q I
Sbjct: 2401 RGFRVEPGEVEACLLALPEVREAVVMPGG-QGADLHLAAWLVPVDGSQADAALRQRILDA 2459
Query: 428 LRSALTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
LR+ L YM+P ++ ++S+PL NGKVDR+ L + VD
Sbjct: 2460 LRAVLPPYMVPSRLQLLDSLPLNPNGKVDRKAL------------PSIEVDTSEEAFSAP 2507
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEISDF 545
+VLGR G F+E GG+SL + + +L RD V + D
Sbjct: 2508 LDALEREVAQAWASVLGRHEVGRF---EHFFEAGGHSLLATQVVARLHRDGHTGVGVRDL 2564
Query: 546 LGASTLGEVLSKM 558
A L + ++
Sbjct: 2565 FSAPRLCDFAQRL 2577
>UniRef50_Q8YTS0 Cluster: Microcystin synthetase B; n=3;
Nostocaceae|Rep: Microcystin synthetase B - Anabaena sp.
(strain PCC 7120)
Length = 1102
Score = 210 bits (514), Expect = 8e-53
Identities = 169/555 (30%), Positives = 263/555 (47%), Gaps = 64/555 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM--FKESGVPFAS 77
++ +L KAG YVP++P++P R+T+I+ + + +V+ +S + F S
Sbjct: 524 VIGILGILKAGGCYVPLDPAYPASRLTYIINETQVPVVLTQESLLEKLLGFTSSQASSKV 583
Query: 78 FEE---LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
+ L + + D + + + ++YTSGSTG PKGV ++ + NRL
Sbjct: 584 LNKTLCLCLDTDWQEITQKPDNNPITNVNHEDAIYIIYTSGSTGTPKGVINTHRGVSNRL 643
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-- 192
+W + + + E+ + KT +F SV E + LL+G L++ +DP L+ I
Sbjct: 644 YWMQQQYGL-ERGEVVLQKTPFSFDVSVWEFFWTLLNGGRLVMSKPGGHQDPNYLLEIIA 702
Query: 193 ----ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG 248
L VPT+L L L L+R+ +CSGE LS E+ + FF++ E
Sbjct: 703 QHKITTLHFVPTMLGVFLEAPNLNERCHSLKRV---ICSGEALSIEIQNRFFQHLDAE-- 757
Query: 249 YKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPG 308
L N YG TE DVTY+ + +D L T+PIGRP+ N IYLL++ L P PG
Sbjct: 758 --LHNLYGPTEAAIDVTYWQCQPTDNLH---TVPIGRPITNTQIYLLNDYLQPVPLGIPG 812
Query: 309 EVWVAGANLAAGY-----------VGGGGA-----------NRFCDNPHATQ-PEFQRLY 345
E+++ G +A GY VGG G N ++ +TQ LY
Sbjct: 813 EIYIGGVGVARGYWKRPDLTTERFVGGLGTGDWGLGTGEKNNPTLNSQLSTQHSALSTLY 872
Query: 346 RTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGN 404
+TGD L G + Y GR D QVKIRG R++L E+E + Q P V + VV+ N
Sbjct: 873 KTGDLARYLPDGNLEYLGRLDNQVKIRGLRIELGEIEAVINQHPDVQQAVVILDSKQADN 932
Query: 405 PEILGFVTTKPGARTS---AQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLL 460
+ +V K + S +E L S L YM+P V + + +PLL NGK++RQ L
Sbjct: 933 QRLGAYVVQKSTSLESPDFTSELEKLLASQLPEYMLPSVFVMLSELPLLPNGKINRQA-L 991
Query: 461 KMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELG 520
E + + + +A + A + R R + + F+ELG
Sbjct: 992 PTPETVRHANQSYIA-----------PRNSTETIIANILADVLRLER--MGVDENFFELG 1038
Query: 521 GNSLNSIYTITKLRD 535
GNSL++I ++LR+
Sbjct: 1039 GNSLSAIRVTSRLRE 1053
>UniRef50_Q5ZTI3 Cluster: Peptide synthetase, non-ribosomal; n=2;
Legionella pneumophila|Rep: Peptide synthetase,
non-ribosomal - Legionella pneumophila subsp. pneumophila
(strain Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 1453
Score = 210 bits (514), Expect = 8e-53
Identities = 165/594 (27%), Positives = 282/594 (47%), Gaps = 62/594 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDS---ADPSMFKESGVPFA 76
++ +L K+G AY+P++P++P RI+++L D++ +L+I D P F +
Sbjct: 661 VICILGILKSGGAYLPLDPNYPDERISYMLMDSKTNLLITDQEFIKRKPHGFNGKSIEIN 720
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDS-IAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
SF L + +E L + S +A ++YTSG+TG PKGV +S+ +ICN +
Sbjct: 721 SFLNLKN----------LSSENLQAINKPSDLAYIIYTSGTTGKPKGVAISHRSICNHML 770
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--E 193
W + + + ++++ + KT +F SV E + PLL G L++ + P +++ + E
Sbjct: 771 WMKKEYAFK-NKDVFLQKTPFSFDASVWEFFMPLLVGGKLVVAPNDAHTSPNQMIRLIRE 829
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V V ++ S+L L + L C GE L E + FFKY N KL N
Sbjct: 830 NKVSVLQIVPSMLKELVSNEEFGLCKSLTHVFCGGEALLSETINAFFKY--NFSDTKLHN 887
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TEV D T Y D IG+P+ N +Y+LD ++ P GE++++
Sbjct: 888 LYGPTEVTIDTTAYTCTAGDAKG--DVSRIGKPIMNTKVYVLDAKMQPVPIGIMGELYIS 945
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKI 370
G LA GY+ +F NP + RLYRTGD VL Y GR D QVKI
Sbjct: 946 GDGLARGYLNNPEFTIQKFLPNPFSNNKN-DRLYRTGDLVKWNSNGVLEYHGRCDNQVKI 1004
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG+R+++ E+E L ++P + +C+V + + ++ + ++ SA I L+
Sbjct: 1005 RGYRIEINEIESYLEKIPSIHQCIVKPEKNQDDSMSLSAYLVLEKNSQISAVDIRAILKQ 1064
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL----LKMYENTN----NNDDAEVAVDIDCS 481
+ YM+P + V+ +GK+DR+ L ++ TN NN ++ +I CS
Sbjct: 1065 NIPEYMIPARFYIVDKFFSTPSGKIDRKMLPIPSKRLRSGTNYAPPNNPKEQLLHNIWCS 1124
Query: 482 XXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVE 541
L + F+ELGGNSL+++ I+ +R++ + +
Sbjct: 1125 VLKI----------------------DNLGIYDDFFELGGNSLSAMNIISHIREQ-FSLT 1161
Query: 542 IS-----DFLGASTLGEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMV 590
+S DF S+L + + + ++ + +P+R E +K + +V
Sbjct: 1162 LSVRTLFDFPTISSLSKAIENIYHKKTDCIYNQSSGNHIIPLRTEGEKTPLFLV 1215
>UniRef50_Q5IW60 Cluster: Phosphinothricin tripeptide synthetase III;
n=2; Streptomyces viridochromogenes|Rep: Phosphinothricin
tripeptide synthetase III - Streptomyces
viridochromogenes
Length = 1189
Score = 210 bits (514), Expect = 8e-53
Identities = 153/455 (33%), Positives = 224/455 (49%), Gaps = 32/455 (7%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ALLA KAG AY+P++P P R ++L+D+ +++ ++ G
Sbjct: 626 FEMVVALLAVLKAGCAYLPIDPGDPAERTAYLLRDSGARVLLTLHRHTANLPDADGTTVV 685
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ +E S D L + +A ++YTSGSTG PKGV + +CNR+ W
Sbjct: 686 TLDE-----PDPSGDMQDTTSALPGIAPGQLAYLIYTSGSTGRPKGVLNEHGPVCNRIRW 740
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IER 194
R FP I + KT + F SV E++ L G L++ + RDPQ L +E
Sbjct: 741 GMRAFPPGPGT-IVLQKTPIHFDVSVWEMFWTLATGATLVLARPDGHRDPQYLAGRLVEE 799
Query: 195 LV----LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
V VP++L + L AL P LRR+ CSGE LS L F + +
Sbjct: 800 GVTDVHFVPSMLAAFLDVGAL-PEGHSLRRV---FCSGEALSPGLRDRLFARLPHVE--- 852
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE +VT++ + PT+PIGRP+ N Y+LD EL+P PGE+
Sbjct: 853 LHNLYGPTEAAIEVTHWRCRPGE-----PTVPIGRPIANARCYVLDAELNPVPPGVPGEL 907
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQ 367
W+ G +A GY G A RF +P+ P R+YR+GD + VL Y GR D Q
Sbjct: 908 WLGGVPVARGYHGRADLTAERFLPDPYG--PAGSRMYRSGDLARWRRDGVLEYLGREDGQ 965
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFV-TTKPGARTSAQHIEG 426
VK+RG R++L E+E LA V VV G + ++ +V +PG +
Sbjct: 966 VKLRGQRLELGEIEATLAGHAEVADVVVDVRGTGPQDRRLVAYVRPARPGRDEQLRTTLR 1025
Query: 427 KLRSA-LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+L +A L YM P + ++ +PL +GK DR+ L
Sbjct: 1026 ELAAARLPAYMRPSSYVTLDRVPLTPSGKTDRKAL 1060
>UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|Rep:
Peptide synthetase - Cyanothece sp. CCY 0110
Length = 2942
Score = 210 bits (514), Expect = 8e-53
Identities = 150/456 (32%), Positives = 226/456 (49%), Gaps = 31/456 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGAAYVP++PS+P RI ++L+D++ S+++ + +
Sbjct: 2128 VIGLLGILKAGAAYVPIDPSYPGDRIAYMLEDSKVSMLLTQGKL-VDQLPVTDASLLCLD 2186
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + ++S D P T+ D +A ++YTSGSTG PKG + I NRL W
Sbjct: 2187 DDWKSLATYSTDNPPHIGTV-----DHLAYMIYTSGSTGKPKGAMNCHRGIVNRLLWMQE 2241
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ S+ I + KT +F SV E + PL+ G L++ E +D L NI + +
Sbjct: 2242 AYQLEASDRI-LQKTPFSFDVSVWEFFWPLMTGATLVVAKPEGHKDSAYLTNIIQQEQIT 2300
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL + +L P LK +CSGE L +L FF + E L N YG
Sbjct: 2301 TLHFVPPMLQVFIEEPDISGCTSLKRVICSGEALPYDLQERFFAHLDCE----LHNLYGP 2356
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DV+Y+ + + L +PIGRP+ N +Y+L++ L P GE+ + G +
Sbjct: 2357 TEAAIDVSYWQCQPNSTL---KKVPIGRPVANTQLYILNQALKPVPVGAVGELHIGGVQV 2413
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHR 374
GY+ A +F ++P + E RLY+TGD L G + Y GR D QVKIRG R
Sbjct: 2414 GKGYLNRPQLTAEKFINDPFSQDAE-ARLYKTGDLCRYLPDGNIEYLGRIDHQVKIRGFR 2472
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK--PGARTSAQHIEGKLRSA- 431
++L E+E L Q P V + VV+ N +++ +V + P IEGKL A
Sbjct: 2473 IELGEIEGVLTQHPDVREVVVIVRQDHFDNKQLVAYVVSPLFPDDDEQVMTIEGKLSQAL 2532
Query: 432 -------LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P + + S+PL NGK+DR+ L
Sbjct: 2533 RDYLKDKLPDYMIPFAFVLLPSLPLTPNGKIDRRSL 2568
Score = 206 bits (502), Expect = 2e-51
Identities = 157/542 (28%), Positives = 261/542 (48%), Gaps = 34/542 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG AYVP++P++P RI +++KD++ ++ + + +P +++
Sbjct: 598 VIGLLGILKAGGAYVPIDPNYPTERINYVIKDSQMRGLLTQNQLIEELTPIE-IPLINWQ 656
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
QEAT+ + + T +TS ++A V+YTSGSTG PKGV++ + ++ N L +
Sbjct: 657 ---QEATTINTYPSNNVTT--SVTSQNLAYVIYTSGSTGKPKGVQIEHQSVVNFLNSMSK 711
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P ++ V T ++F + E++ PL+ G +L+ S+ET D +KL ++ +
Sbjct: 712 Q-PGLSQDDNLVAVTTISFDIAALELYLPLIRGGTILLASQETASDGEKLAHLLQNSCTT 770
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + + L A+ + +C GE L LA + ++ +L N YG TE
Sbjct: 771 IMQATPATWRMLIAANWTGKSNLKILCGGEALPTSLAEQL-----HQSSRELWNVYGPTE 825
Query: 260 V-MGDVTYYVLEGSDQLDLYPTIP-IGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
+ Y V S LD+ T+ IG P+DN +YLLD L P GE+++ G L
Sbjct: 826 TTIWSSVYCVKSLSKTLDIAKTVQSIGHPIDNTQMYLLDSNLEPVPIGVAGELYIGGDGL 885
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A +F NP + RLY+TGD L G + Y GR D QVKIRG R
Sbjct: 886 ARGYLNRPELTAEKFIPNPFDPTGK-TRLYKTGDLCRYLPDGNIEYIGRIDHQVKIRGFR 944
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP-GARTSAQHIEGKLRSALT 433
++L E+E L P V + VV+ GN ++ ++ T+ G + Q + L+ L
Sbjct: 945 IELGEIESLLTSHPEVQESVVIAREDQPGNKRLVAYIVTQEVGEDSLNQTLRDYLKGQLP 1004
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P + +E +PL NGK+DR+ L D D
Sbjct: 1005 DYMIPSAFVFIEKLPLTPNGKIDRKAL--------PAPDFSAMAQAD----FVAPSTDRE 1052
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLG 552
V + + R + +S+ S F+ELGG+S+ +I + + + G + T+
Sbjct: 1053 QILAQVWSEVLRIEK--ISINSNFFELGGDSILTIQIVARAKQAGLRISPKQLFEHQTIA 1110
Query: 553 EV 554
E+
Sbjct: 1111 EL 1112
>UniRef50_Q0B1F6 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 3018
Score = 210 bits (513), Expect = 1e-52
Identities = 145/449 (32%), Positives = 228/449 (50%), Gaps = 31/449 (6%)
Query: 22 ALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEEL 81
A+LA WK GAAY+P++P +P RI IL+D+ +LVI D P P S + +
Sbjct: 515 AILAVWKCGAAYIPIDPDYPAARIRTILEDSGAALVITCDGLLPPELAALA-PVVSLDTV 573
Query: 82 AQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTF 141
+ DE ++P DS+A V+YTSGSTG PKG + ++ + N + + F
Sbjct: 574 TE-----GGDETNPGRPVSP---DSLAYVIYTSGSTGKPKGAMVEHAGMLNHMLAEIDEF 625
Query: 142 PYSDSEEICVWKTALTFVD-SVCEIWGPLLHGRALLILSRETTRDPQKLV------NIER 194
S S I +TA D SV + + L G +I+ RDP V I
Sbjct: 626 SISASSVIA--QTAPHCFDISVWQFFTAPLVGGKTVIVDDACIRDPASFVATLEAARISI 683
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
L LVP+ L ++L + + PA LR L+ + +GE +S L +F F + + N
Sbjct: 684 LELVPSYLSAVLDHASEAPAL--LRHLRHLLVTGEMVSPALVKRWFDVFAD---IAVVNA 738
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG E DV + + + P +P+G+P+ N IY++D +++ PGE+ V+G
Sbjct: 739 YGPAEASDDVAQHRMTCAPTT---PYVPVGKPIRNVRIYVVDPQMNLCPIGVPGELCVSG 795
Query: 315 ANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
+ GY+ R F ++P + R+YRT D G L G+++ GR D Q+KIR
Sbjct: 796 VAVGRGYLNNEAGTREAFLEDPFRAESGV-RMYRTRDIGCYLPDGSIVLHGRKDHQLKIR 854
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G+R++L E++ ALA +P + + L Y D G + +V + GA S I L +
Sbjct: 855 GYRIELGEIDNALAAIPEIRQAAALDYRDDAGRAALCAYVAFRAGASLSDAEIAAALSAT 914
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + + ++++PL NGK+DR+ L
Sbjct: 915 LPDYMVPGIYVVLDALPLSGNGKIDRKAL 943
Score = 190 bits (464), Expect = 9e-47
Identities = 160/559 (28%), Positives = 257/559 (45%), Gaps = 49/559 (8%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELA 82
+LA WK GAAYVP++P++P R+ IL A P++++ D P + +P + A
Sbjct: 2026 ILAIWKCGAAYVPVDPAYPAQRVETILTLARPTVIVATDCVPPPAL--ASIPLV---DPA 2080
Query: 83 QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFP 142
+ H A P A +A V++TSGSTG PKG + + + N + R
Sbjct: 2081 RLPDPHGAGAP--APVTPRCRPVDLAYVIFTSGSTGQPKGAMVEHRGMLNHVLAMARRVE 2138
Query: 143 YSDSEEICVWKTALTFVD-SVCEIWGPLLHGRALLILSRETTRDPQKLVN------IERL 195
+ V +TA D SV + + L+ G +I +P +L++ I +
Sbjct: 2139 L--GAQSAVAQTASHCSDISVWQCFAALVSGGTTVIYPDAVILEPARLIDSLQRDRITAM 2196
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
VP+ L + L L A+ L + GETL A +F+ G +L N Y
Sbjct: 2197 QFVPSYLATFLGELET-HAAPAFPHLDTLLTIGETLQPATAQAWFRL---NPGVRLINAY 2252
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE V +Y +E + L P IPIGRP++N +Y++D +++ GE+ + GA
Sbjct: 2253 GPTEASDSVAHYSMERAPDL---PAIPIGRPIENLRVYVVDADMNLCPVGVKGEICIGGA 2309
Query: 316 NLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
+ GY+ R F D+P + +P RLYRTGD G G + + GR D QVKIRG
Sbjct: 2310 GVGRGYLFDEARTRAVFRDDPFSPEPG-ARLYRTGDVGCFGSDGNLHFFGRRDFQVKIRG 2368
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
+R++L E+E AL + G+ VV+ + G+ + G + + + LR L
Sbjct: 2369 YRIELGEIETALTGLAGISNAVVVVRDTPDAEKTLCGYAS---GTGWTPKRLRDALRDKL 2425
Query: 433 THYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
+M+P + + ++P++ NGK++R L + E + D V
Sbjct: 2426 PAHMVPDTLMLLSALPVMPNGKINR-AALPLPEAASVPDGVPV----------EPRTPVE 2474
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEISDFLGAST 550
VLGR G + F+E GG SL +I ++++ R+ V ++D A +
Sbjct: 2475 AALLRIFAEVLGRQPGG---VDDNFFEHGGQSLKAIQMVSRIRRELKLNVAVADIFHAPS 2531
Query: 551 ---LGEVLSKMSTDPNGGA 566
L + L+ D GGA
Sbjct: 2532 PRALAQKLASTPADDAGGA 2550
>UniRef50_Q3M1N0 Cluster: Amino acid adenylation; n=2; Bacteria|Rep:
Amino acid adenylation - Anabaena variabilis (strain ATCC
29413 / PCC 7937)
Length = 2867
Score = 210 bits (512), Expect = 1e-52
Identities = 164/584 (28%), Positives = 274/584 (46%), Gaps = 35/584 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +LA KAGAAYVP++PS+PQ R+ I++DA+ +++ + V S +
Sbjct: 567 IVGILAILKAGAAYVPLDPSYPQERLAFIIQDAQLEVLLTQQQL-LEVLPPHQVQVISLD 625
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
Q + P T+ ++A ++YTSGSTG PKGV + + + RL+ +
Sbjct: 626 RDWQIIAQENQANPACTATVG-----NLAYIIYTSGSTGQPKGVLVPHQNV-TRLFEAVQ 679
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + +++ ++ F SV E+WG LLHG L+I+ +R P+ + V
Sbjct: 680 PWFEFNQQDVWTLFHSIAFDFSVWELWGALLHGGKLVIVPYWLSRSPEAFYQLLCKQKVT 739
Query: 200 TLLRSILMYLALGPASRPLRR---LKLWVCSGETLSKELASEFFKYFGNEDGY-KLANFY 255
L ++ + L A P L+L + GE L + + G D Y +L N Y
Sbjct: 740 VLNQTPSAFRQLIQAKEPFNHQLALRLVIFGGEALEISSLQPWCERHG--DRYPQLVNMY 797
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE VTY + +D L + IGRP+ + +Y+LD+ GE+++ G
Sbjct: 798 GITETTVHVTYRPITMAD-LQVNSGSIIGRPIPDLQVYILDQHQQLVPIGVSGEMYIGGG 856
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
LA GY+ +F +P + QP+ RLY++GD L G + Y GR D QVKIRG
Sbjct: 857 GLAKGYLNRPDLTTEKFIPHPFSNQPD-ARLYKSGDLARYLPNGDIEYLGRIDHQVKIRG 915
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+ L Q P V + VVL G ++ +V + + + L+ L
Sbjct: 916 FRIELGEIAGILTQHPSVQETVVLAKETSSGEKYLVAYVVFRHQQTPTTSQLRNFLKKQL 975
Query: 433 THYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P V + VE++PL NGK+D Q L + + D A V+
Sbjct: 976 PDYMLPSVFVVVEALPLTANGKLDHQALPEPSTSRPELDTAFVS----------PRTATE 1025
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
VLG A G + F+ LGG+S+ SI + ++RG Y + T+
Sbjct: 1026 KILTEIWSQVLGFAEIG---IYDNFFALGGDSIRSIQVRSLAQERGLYFSLQQIFQHQTI 1082
Query: 552 GEVLSKMSTDPNGGADSKE-ATFTAVPMRDEHKKEVIDMVESSF 594
E+++ + N A ++ A F+ + ++ + ++ + +E ++
Sbjct: 1083 HELIADVVIAENPQATTQSIAAFSLI--SEQERSQLPENIEDAY 1124
Score = 145 bits (352), Expect = 3e-33
Identities = 112/401 (27%), Positives = 191/401 (47%), Gaps = 21/401 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KA AYVP++PS+PQ R+ +L+DA+ +++ P F + +
Sbjct: 1645 LVGILGILKACGAYVPLDPSYPQQRLDFMLQDAKIEILLTQKHLLPK-FSHHNIKIICID 1703
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ HS DA +TSD++A ++YTSGSTG+PKGV +++ + + +
Sbjct: 1704 TEWEAIAQHS-----DAHPECEITSDNLAYIIYTSGSTGLPKGVEITHKNLIHSTIARIN 1758
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+P D + + ++ F SV I+ L G L + ++ +KLV + +
Sbjct: 1759 YYPEYDVNFLLL--SSFAFDSSVAGIFWTLCCGGTLYLPQVGEEKEVRKLVKLISQYQIS 1816
Query: 200 TLLRSILMY-LALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
LL +Y L L A L L + +GE K+L + Y N YG
Sbjct: 1817 HLLSLPSLYALILEQAEIAQLTSLHTVIVAGEPCPKKLVQSHCELLKTTSLY---NEYGP 1873
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + + + +IPIGRP+ N IY+L+ + GE+++ G +
Sbjct: 1874 TEA---TVWSSVYNCSWPEAGISIPIGRPIHNTQIYILNSDGKLVPVGVTGELYIGGDGI 1930
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+G A +F + + +P RLY+TGD G + + GR+D QVKIRG R
Sbjct: 1931 ARGYLGKPQLTAEKFIPDFFSDEPG-ARLYKTGDLARYRPDGNIEFLGRSDRQVKIRGFR 1989
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP 415
++L E+E L Q P + + V+ + +G+ ++ ++ P
Sbjct: 1990 IELGEIEAVLEQHPTIREVAVVSREI-QGDLRLVAYIVPSP 2029
>UniRef50_A5XI24 Cluster: Non-ribosomal peptide synthase; n=23;
Burkholderia|Rep: Non-ribosomal peptide synthase -
Burkholderia mallei FMH
Length = 3297
Score = 210 bits (512), Expect = 1e-52
Identities = 152/458 (33%), Positives = 231/458 (50%), Gaps = 32/458 (6%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYD----DSADPSMFKESG 72
F ++AL+ T KA AAY+P++P +P RI ++L DA+P +VI D ++
Sbjct: 2748 FDMVVALVGTMKARAAYLPVDPDYPAERIAYLLGDAKPPVVITQAHLRARVDAALAGADA 2807
Query: 73 VPFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN 132
E LA+ A + E + A A + +A ++YTSGSTG PKG ++ A+ N
Sbjct: 2808 AVVTVDELLARAAGAEPEAERVAA--AADVAPGQLAYLIYTSGSTGQPKGAGNTHGALAN 2865
Query: 133 RLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV-- 190
R+ W R + + +++ + KT F SV E PL G L I + RDP +LV
Sbjct: 2866 RIAWMQRAYRLA-PDDVVLHKTPFGFDVSVWEFVWPLAVGAKLAIAAPGDHRDPARLVAA 2924
Query: 191 ----NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNE 246
+ L VP++L + + YL A+ ++ V SGE L+ EL + +
Sbjct: 2925 IDAHRVTTLHFVPSMLAAFVAYLDDFGAAARCASVRTIVASGEALAPELVARVAALLPHA 2984
Query: 247 DGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSE 306
+L N YG TE DV+++ D +PIG P+ N +++LD L P
Sbjct: 2985 ---QLHNLYGPTEAAIDVSHWRCTADDA--AADAVPIGHPIANLRLHVLDAALHPAPVGA 3039
Query: 307 PGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGR 363
GE+++ GA LA GY+G A RF +P RLYRTGD GA+ Y GR
Sbjct: 3040 TGELYLGGAGLARGYLGRAALTAERFVPDPFVPG---ARLYRTGDLARRRADGALDYLGR 3096
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQ 422
D QVK+RG R++L E+E L GV VV+ + ++G+V P +A
Sbjct: 3097 LDTQVKLRGQRIELGEIEALLRATDGVRDAVVIV-----RDERLVGYVACATPAGFDAAA 3151
Query: 423 HIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
IE +LR+ L YM+P Q++ ++++P+ NGK DR+ L
Sbjct: 3152 QIE-RLRARLPAYMVPAQLVALDALPVTPNGKCDRRAL 3188
Score = 149 bits (362), Expect = 2e-34
Identities = 147/552 (26%), Positives = 225/552 (40%), Gaps = 43/552 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A L K+GA VP++P+ P+ RI L ++ + D ++ + GV +
Sbjct: 1189 VVAFLGVLKSGAYAVPLDPASPRERIAAALAACGACRMLAAGALD-ALGEFDGVAVQDID 1247
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+A+ +A P P + A +++TSGSTG PKGV + + A+ + +
Sbjct: 1248 ACGHDASLANAAAPR-----VPPQPEQAAYLIFTSGSTGAPKGVVVPHRALADYVAGMLD 1302
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLVL 197
++ + + T + ++G L GR L +L + DP + + R V
Sbjct: 1303 ELAFAPHASMAMVSTVAADLGHTT-LFGALCSGRTLHLLPAQAAFDPDRFAHEMATRKVG 1361
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V ++ S L L + + V GE L L + ++ N YG
Sbjct: 1362 VLKIVPSHLHALLDAQRAADVLPAHALVTGGEALPWALVERIAAL---KPDCRVINHYGP 1418
Query: 258 TEVMGDVTYYVLEGSDQLDLYPT-----------IPIGRPLDNCAIYLLDEELSPTRDSE 306
TE Q DL +P+GRPL N +LD S
Sbjct: 1419 TEASVGALVCDTSAPAQADLRAAAASSPGEAARGVPLGRPLPNAHACVLDAYGSSVPVGA 1478
Query: 307 PGEVWVAGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGR 363
GE+++ G LA GY+G A RF +PH R+YRTGD L G + + GR
Sbjct: 1479 IGELYLGGPGLARGYLGRAAASAERFVPHPHVAGA---RVYRTGDRVRLRADGRLDFLGR 1535
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQH 423
D QVKIRG+RV+ EV AL +PGV + L G + F T + GAR +A
Sbjct: 1536 LDDQVKIRGYRVEPGEVSAALRALPGVAQAETLALE-HEGRLRLAAFATPEAGARIAADA 1594
Query: 424 IEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSX 482
+ L + L YM+P + V +++P+ NGK+DR L A D D
Sbjct: 1595 LRDALAARLPDYMVPAALVVLDALPVTANGKIDRAAL----RARAAAPAPATAGDEDAPQ 1650
Query: 483 XXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
A +GR F+ELGG+S+ + I + R RG
Sbjct: 1651 GPIEATLAEVWRDVLKAARVGR--------HDNFFELGGDSILVLQVIARARKRGVKFTP 1702
Query: 543 SDFLGASTLGEV 554
TL E+
Sbjct: 1703 KQLFDGPTLAEL 1714
Score = 117 bits (281), Expect = 1e-24
Identities = 138/483 (28%), Positives = 210/483 (43%), Gaps = 47/483 (9%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ALLA KAG A+V ++P P R+ + +DA + I D SAD +M A F
Sbjct: 74 VALLAVMKAGGAFVALDPRHPAARLDWVARDAGLAHGIVDASADAAM-------RARFAR 126
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
+AD E + + A ++YTSGSTG PK V + + + +
Sbjct: 127 CFDVGGVAAADPAAPREHGGDVHPRAAAYMIYTSGSTGTPKAVVVEHGPLAAHGDALAES 186
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRE--TTRDPQKLVNIERL-- 195
P + + + ++ F D E W PL G +++I T L++ ER+
Sbjct: 187 LPIGPDDRVLHF-ASVNF-DVAIEAWLVPLAVGGSVVISDPPPFTPDAAHALISRERVTN 244
Query: 196 -VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
L P LR A LR L + GE +S++ E + F +L N
Sbjct: 245 TTLPPAYLREFAAVCAREGVPPSLRVL---LFGGEAMSQDAFDEIRRVF---PAIRLVNG 298
Query: 255 YGSTE-VMGDVTYYVLEGS----DQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
YG TE V+ + + V G+ D + Y ++PIG P+ + ++ E GE
Sbjct: 299 YGPTETVISPMLWPVAPGTTPALDAGNGYASLPIGWPIGR-RVARVERADGTVARGEAGE 357
Query: 310 VWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDA 366
+ + GA LA GY G A RF +P A +P R+YRTGD GA Y GR D
Sbjct: 358 LLLGGACLARGYHGRAALTAERFLPDP-AGEPG-ARIYRTGDLARERADGAFDYLGRIDD 415
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGART----SA 421
QV++RG RV+ E+ L PGV VL G +++ V P T A
Sbjct: 416 QVQVRGVRVEPAEIAACLLTHPGVRDAGVLAETAG-GRTQLIACVALAAPPRETPSGGDA 474
Query: 422 QHIEGKLRSALTHYM----MP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAV 476
+ LR+ + ++ +P + + + +P +NGK+DR L + AE A
Sbjct: 475 PPDDDALRAHVAAHLPAAWLPHRFVRFDKLPYTLNGKLDRVAL----RDAVAARPAEAAA 530
Query: 477 DID 479
D+D
Sbjct: 531 DVD 533
>UniRef50_A5EHY7 Cluster: Non ribosomal peptide synthase; n=1;
Bradyrhizobium sp. BTAi1|Rep: Non ribosomal peptide
synthase - Bradyrhizobium sp. (strain BTAi1 / ATCC
BAA-1182)
Length = 1134
Score = 210 bits (512), Expect = 1e-52
Identities = 147/447 (32%), Positives = 229/447 (51%), Gaps = 24/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLAT +AGAAY+P++P P+ RI +++DA P LV+ + + A +
Sbjct: 604 VVALLATLEAGAAYLPLDPRDPRPRIAQMIEDAAPVLVLVGAEFEDHL-------CAGID 656
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L + +A + ++AP D +A +++TSGSTG PKG L++ + NR+ W +
Sbjct: 657 QLTVDPLGAAAGPEAECPSVAP---DDLAYIIFTSGSTGRPKGAMLTHGGVANRIVWMQK 713
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER-LVLV 198
+ ++ I + KT TF SV E PL+ G L++ + +DP+ + + R +
Sbjct: 714 HYGLQPTDRI-LQKTPYTFDVSVWEFLLPLISGAELVVAPPDAHKDPRAIAGLIRDRGIT 772
Query: 199 PTLLRSILMYLALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
++ + LG A L LK CSGE L +A++ + + L N YG
Sbjct: 773 DIHFVPAMLSVFLGNADLADLVSLKRIYCSGEALPTAVAAQCRARLAHAE---LHNLYGP 829
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DV+ + + D + + P+G P+DN +++LD L P PGE+ +AG +
Sbjct: 830 TEASIDVSAWCCDIGD-AERHAVAPLGWPVDNTELHILDGRLLPMPLGVPGELCIAGIGV 888
Query: 318 AAGYVGGG--GANRFCDNPHAT-QPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIRGH 373
A GYV RF NP A P RLYRTGD L GA+ + GR D QVKIRG
Sbjct: 889 ARGYVSRPELTRERFVGNPFADGVPHMARLYRTGDVARRLPDGAIEFLGRRDFQVKIRGF 948
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
RV+L E+E L + V + VV D G + ++ + G R +LR L
Sbjct: 949 RVELGEIEAVLLEQSDVAQAVVARRATD-GRELTVAYLVGRNG-RPDLARTHERLRQRLP 1006
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P +I ++++PL NGK+DR+ L
Sbjct: 1007 DYMVPDHIIVLDALPLSANGKLDRKQL 1033
>UniRef50_Q3WDU5 Cluster: Amino acid adenylation; n=1; Frankia sp.
EAN1pec|Rep: Amino acid adenylation - Frankia sp. EAN1pec
Length = 2547
Score = 209 bits (511), Expect = 2e-52
Identities = 144/453 (31%), Positives = 229/453 (50%), Gaps = 22/453 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAGAAY+P++ ++P R+ +L DA P ++ A P++ + VP + +
Sbjct: 1540 VVALLAVQKAGAAYLPLDTAYPADRLAFMLSDAAPVCLVTSAEALPALPARTRVPMIALD 1599
Query: 80 ELAQEATSHSADE-PMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A + A++ P ++ A V+YTSGSTG PKGV + + + RL+
Sbjct: 1600 --APPVVAALAEQSPARLPAAGRARPENAAYVIYTSGSTGRPKGVVVPHQTV-TRLF--A 1654
Query: 139 RTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
T P+ +E VW + +F SV E+WGPLL+G L+++ +R P+ +++ R
Sbjct: 1655 HTQPWFGFDETDVWTMFHSASFDFSVWELWGPLLYGGRLVVVDHHVSRSPELFLDLLRRE 1714
Query: 197 LVPTLLRSILMYLALGPASR-----PLR-RLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
V L ++ + L A R P L+ V GE L ++ +D
Sbjct: 1715 SVTVLSQTPSAFSQLIEADRAGGEDPAELALRYVVFGGEALDLGRLPAWYARH-RDDAPV 1773
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE VTY L+ + ++ +G P+ +++LD+ L P GE+
Sbjct: 1774 LVNMYGITETTVHVTYLRLDEAVVAAARASL-VGGPIPGLRVHVLDQHLRPVAPGGLGEL 1832
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQ 367
+V+G LA GY+G G A RF +P R+YRTGD G Y GR D Q
Sbjct: 1833 YVSGGQLARGYLGRPGLTATRFVADPFGGPGA--RMYRTGDLARRTADGGFEYLGRADDQ 1890
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VK+RG R++L E++ A+A P V++ VVL G ++G+V PG R ++ +
Sbjct: 1891 VKVRGFRIELGEIQAAIATHPAVEQAVVLAREDQPGQRRLVGYVVAAPGRRVDSEELRRH 1950
Query: 428 LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L +M+P V+ +++ PL NGK+DR L
Sbjct: 1951 AAAMLPEFMVPVAVLALDAFPLTGNGKLDRAAL 1983
Score = 178 bits (434), Expect = 4e-43
Identities = 139/452 (30%), Positives = 213/452 (47%), Gaps = 27/452 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGV------ 73
++AL +AGAAY+P++P +P RIT +L+DA PSL+I ++ +GV
Sbjct: 410 VVALAGVTRAGAAYLPVDPGYPADRITLVLEDAAPSLLITTRELAATLPIPAGVTVVLVN 469
Query: 74 -PFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN 132
P A E + T + A P S A V+YTSGSTG PKGV + + A+ N
Sbjct: 470 GPAAGPEAGTEFGTEFGSVPEPPAAAAVPAELGSAAYVIYTSGSTGRPKGVVVPHRALTN 529
Query: 133 RLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI 192
L F D + + T L+F + E+ PL G + + ++ RDP L +
Sbjct: 530 FLASMVDQFQLGDGDRVLA-LTTLSFDIAALELLAPLTAGATVHLAGQDEARDPTALAAL 588
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+ + M+ ++ AS + GE L +A+ E ++
Sbjct: 589 LAGGGITVAQATPSMWQSILAASDDRFPGVRVLSGGEGLPPAVAATL-----AERADEVV 643
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE T + G D PT +GRP+ + +YLLD L+P PGE+++
Sbjct: 644 NLYGPTE----TTIWSTAGPVAGDGRPT--VGRPIRSTQVYLLDTALAPVAPGMPGELYI 697
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
GA +A GY+ G A+RF +P + RLYRTGD G + GR D QVK
Sbjct: 698 GGAGVADGYLRRPGLTASRFVADPFSAG---GRLYRTGDLARWTADGELDVLGRVDDQVK 754
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGKL 428
+RG R++ EVE L + P V +C V+ ++ +V PG + L
Sbjct: 755 VRGFRIEPGEVEAVLGRHPAVARCAVVARDDGPAGRHLVAYVVPAAPGTVVDPALLREHL 814
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+AL +M+P +++ ++P NGK+DR+GL
Sbjct: 815 AAALPEHMVPGAFVQLAALPTTPNGKLDRRGL 846
>UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomonas
syringae pv. syringae|Rep: Amino acid adenylation -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 9498
Score = 209 bits (510), Expect = 2e-52
Identities = 163/542 (30%), Positives = 261/542 (48%), Gaps = 36/542 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYD-DSADPSMFKESGVPFASF 78
++ALL KAG AYVP++P P R ++L+D+ P V+ D +D + V
Sbjct: 578 VVALLGILKAGGAYVPIDPDLPSARQAYMLEDSSPQAVLTTRDLSDNLPASDHPVLVLDG 637
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + S P DA+ L L + +A VLYTSGSTG PKGV + + NRL W
Sbjct: 638 HDDRAQLASQPTGNP-DAKALG-LQPNHLAYVLYTSGSTGTPKGVMNEHLGVVNRLLWAR 695
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
+ + + + + KT F SV E + PLL G L++ +DP L + + +
Sbjct: 696 DAYQVNSQDRV-LQKTPFGFDVSVWEFFLPLLTGAELVMARPGGHQDPDYLAQVMSDAGI 754
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ + S+L ++R +L+ +CSGE L + L F ++ G +L N YG
Sbjct: 755 TLLHFVPSMLDVFLEHRSTRDFPQLRRVLCSGEALPRALQRRFEQHL---KGVELHNLYG 811
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDE--ELSPTRDSEPGEVWVAG 314
TE DVT + +D + ++PIGRP+ N +++LD +L P GE+ + G
Sbjct: 812 PTEAAIDVTAWECRPTDPGE---SVPIGRPIANIQMHVLDTLGQLQPL--GVAGELHIGG 866
Query: 315 ANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
+A GY+ A RF +P ++ P+ RLY+TGD G L GA+ Y GR D QVKIR
Sbjct: 867 IGVARGYLNQPDLSAERFIADPFSSDPQ-ARLYKTGDVGRWLANGALEYLGRNDFQVKIR 925
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGKLRS 430
G R+++ E+E ALA+ P V + VV G+ ++ + T + + + L+
Sbjct: 926 GLRIEIGEIEAALAKHPAVHEAVVTAREDIPGDKRLVAYYTQSAEHTAVDLEILRSHLQQ 985
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P + + +E++PL NGK+DR+ L + DA ++ +
Sbjct: 986 QLPEYMVPAIYVLLEAMPLTSNGKLDRKAL------PAPDGDALISRGYEAPQGEVETLL 1039
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
+GR F+ELGG+SL ++ I ++R G ++ G
Sbjct: 1040 ASIWADVLKVEQVGR--------HDHFFELGGHSLLAVKLIERMRQVGLSADVHVLFGQP 1091
Query: 550 TL 551
T+
Sbjct: 1092 TV 1093
Score = 202 bits (494), Expect = 2e-50
Identities = 148/452 (32%), Positives = 231/452 (51%), Gaps = 26/452 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA--- 76
++ALL KAG AYVP++P P R ++L+D+ P V+ ++ S +P
Sbjct: 1668 VVALLGILKAGGAYVPIDPDLPSARQAYMLEDSSPQAVLTTRDLSDNL-PASDLPVLVLD 1726
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
++ AQ A S + DA+ L L + +A VLYTSGSTG PKGV + + NRL W
Sbjct: 1727 GHDDRAQLARQQSVNP--DAKALG-LQPNHLAYVLYTSGSTGTPKGVMNEHLGVVNRLLW 1783
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ER 194
+ + + + + KT F SV E + PLL G L++ +DP L + +
Sbjct: 1784 ARDAYQVNSQDRV-LQKTPFGFDVSVWEFFLPLLTGAELVMARPGGHQDPDYLAQVMSDA 1842
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ + + S+L ++R +L+ +CSGE L + L F + G +L N
Sbjct: 1843 GITLLHFVPSMLDVFLEHRSTRDFPQLRRVLCSGEALPRALQRRFEQQL---KGVELHNL 1899
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDE--ELSPTRDSEPGEVWV 312
YG TE DVT + +D D ++PIGRP+ N +++LD +L P GE+ +
Sbjct: 1900 YGPTEAAIDVTAWECRPTDPGD---SVPIGRPIANIQMHVLDALGQLQPL--GVAGELHI 1954
Query: 313 AGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
G +A GY+ A RF +P + + RLY+TGD G L GA+ Y GR D QVK
Sbjct: 1955 GGIGVARGYLNQPDLSAERFIADPFSEDRQ-ARLYKTGDVGRWLANGALEYLGRNDFQVK 2013
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGKL 428
IRG R+++ E+E ALA+ P V + VV G+ ++ + T + + + L
Sbjct: 2014 IRGLRIEIGEIEAALAKHPAVHEAVVTAREDIPGDKRLVAYYTQSAEHTAVDLEILRSHL 2073
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ L YM+P + + +E++PL NGK+DR+ L
Sbjct: 2074 QQQLPEYMVPAIYVLLEAMPLTSNGKLDRKAL 2105
Score = 201 bits (490), Expect = 7e-50
Identities = 165/572 (28%), Positives = 262/572 (45%), Gaps = 40/572 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I A+LA K+GAAYVP++P++P R+ ++L D+ P + + SA + VP +
Sbjct: 7032 ICAVLAVLKSGAAYVPLDPTYPTERLGYLLTDSAP-VALLAQSACLDVLPAHSVPVLTLG 7090
Query: 80 ELAQEATSHSADEPMDAE---TLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
A ++ ADE +D L+ + +A V+YTSGSTG+PKGV + + +
Sbjct: 7091 --ADNDSADLADESLDRNPEPAALGLSREHLAYVIYTSGSTGLPKGVLVEHGNVARLFDA 7148
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ER 194
F + E++ + F SV EIWG L +G L+I+ E R P + E+
Sbjct: 7149 TAGQFNFGH-EDVWTLFHSFAFDFSVWEIWGALCYGGKLVIVPSEVARSPDDFYALVCEQ 7207
Query: 195 LVLV----PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
V V P+ R + P LR + V GE L + +
Sbjct: 7208 QVTVLNQTPSAFRQFIQARERSPQEHALREV---VFGGEALDFRSLQPWTARTPLSRT-R 7263
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE+ TYY + S+ P++ IG LD+ + +LD+ P GE+
Sbjct: 7264 LVNMYGITEITVHATYYPISQSEIDTAMPSL-IGPALDDLCLRILDDYQQPVPVGVNGEI 7322
Query: 311 WVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQ 367
++ GA +A Y+ A RF +P+A Q RLYRTGD G V+Y GR D+Q
Sbjct: 7323 YIGGAGVARHYLNRTELNAERFIADPYALQSG-ARLYRTGDVAHYRSDGGVVYVGRNDSQ 7381
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
+KIRG R++L E+E L P V + +V+ G+ ++ ++ + GA + + +
Sbjct: 7382 IKIRGFRIELGEIEAQLLACPDVREAMVIVREDRPGDKRLVAYLIAEDGAAPESALLRSQ 7441
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L S L +M+P + +E+ PL NGK+DR L + A V+ D +
Sbjct: 7442 LASVLAEHMLPSAFVTLETWPLTTNGKLDRAAL------PAPDQFATVSRDYEAPLGAIE 7495
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
+GR + F+ELGG+S I I +LR G +++S
Sbjct: 7496 TTLAAAWQELLGVERVGR--------QDHFFELGGHSFLVISLIERLRQIGLLLDVSTVF 7547
Query: 547 GASTLGEVLSKMSTDPNGGADSKEATFTAVPM 578
A TL + + ++ G A + A +P+
Sbjct: 7548 SAPTLQAMAAVLA---GGTAAERVAPANLIPV 7576
Score = 184 bits (448), Expect = 8e-45
Identities = 137/473 (28%), Positives = 231/473 (48%), Gaps = 34/473 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAGAAYVP++P++P R+ ++++D+ PS ++ + +P +
Sbjct: 4907 LIGVLGVLKAGAAYVPLDPAYPAERLAYMIEDSTPSALLAQRDVQAHL-PTLDLPLVLLD 4965
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAI--CNRLWWQ 137
E + S D P+ ETL + ++A V+YTSGSTG+PKGV + + + + W Q
Sbjct: 4966 EDQRTTLSERGDNPV-VETLG---AHNLAYVIYTSGSTGVPKGVMVEHRGLFAVSAAWEQ 5021
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERL 195
++ + + +F ++ L G L++ RET DP L + E
Sbjct: 5022 LYAL-HAPLNHLQM--AGFSFDVFSADLIRSLAFGGTLVLCPRETLMDPPALYRLLSEES 5078
Query: 196 V----LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ VP +L ++L ++ L ++ VC + + A + K G D ++
Sbjct: 5079 IGFADFVPAVLNALLGWVE--ETGHDLSFMRTVVCGSDIWTAHSARQLRKLCG--DHVQI 5134
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
YG TE D T + E + Q+D +PIGR L N IYLLDE GE++
Sbjct: 5135 VQAYGVTEASIDSTCFEFEATSQVD--GVLPIGRALANTRIYLLDELGQAVPPGVAGELY 5192
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+ GA +A GY+ A RF DNP +RLYR+GD G + + GR D+Q
Sbjct: 5193 IGGAGIARGYLNLQQLTAERFMDNPFVAG---ERLYRSGDMARYRADGNIEFLGRNDSQA 5249
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGF-----VTTKPGARTSAQH 423
K+RG R++L E+E LA+V GV + +V+ G P+++ + + G + +
Sbjct: 5250 KLRGLRLELGEIEARLAEVAGVRESLVVIREDSGGTPKLIAYFVEYATRDESGPALTPRA 5309
Query: 424 IEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVA 475
+ +L+ L YM+P + + ++PL NGK+DR+ L + + + D E A
Sbjct: 5310 LRQQLQLNLPEYMIPAAFVRMAALPLSANGKLDRRALPEPDADAFDQHDFEAA 5362
Score = 179 bits (436), Expect = 2e-43
Identities = 135/447 (30%), Positives = 222/447 (49%), Gaps = 25/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIY-DDSADPSMFKESGVPFASF 78
+ ++LAT K GAAY+ ++ P+ R+ +L+D+E +++ D P M P
Sbjct: 5974 LASMLATLKCGAAYLALDRLAPEERLRFMLEDSEAIMLLSRSDLTAPDM-----TPRLDL 6028
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ L A + EP+ T + ++ A ++YTSGSTG+PKGV ++++ I RL
Sbjct: 6029 DTLELSALNQ---EPVVPAT--EVAGETPACIIYTSGSTGVPKGVIVTHNGIV-RLVQDN 6082
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ +S +E+ + + F S EIWG LL+G +I+ + +P + + V
Sbjct: 6083 GYYDFS-AEDRVAFSSNPAFDASTPEIWGALLNGGQSVIIEPQVLLEPVAFAALLKRHGV 6141
Query: 199 PTLLRSILMY-LALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
++ S ++ L G L L++ +C GE + F + + +L N YG
Sbjct: 6142 TAMISSTALFNLYAGLIPEALAGLRMIMCGGERADP---ASFRRVREHSAQVRLFNGYGP 6198
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T Y E D L ++PIG+P N +Y+LD P GE+++ G +
Sbjct: 6199 TEGTTCATSY--EIFDVLPDTLSLPIGKPNANVRVYVLDARREPVPMGVVGEIYIGGTGV 6256
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF ++P + Q RLYRTGD L G + Y R D QVK+RG R
Sbjct: 6257 ALGYLNRPELTAERFSEDPFSQQAG-ARLYRTGDLARWLPDGNLEYLARNDGQVKVRGFR 6315
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLRSALT 433
V+L E+E L GV VV+ + G+ ++ + T G + + +L + L
Sbjct: 6316 VELGEIESVLHLCDGVRNSVVVAHEASPGDTRLVAYYTVHAGVDAPDPEDLRAQLSADLA 6375
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P V + ++++PL +NGKVD++ L
Sbjct: 6376 EYMVPSVFVRLDALPLTLNGKVDQKAL 6402
Score = 179 bits (435), Expect = 3e-43
Identities = 152/553 (27%), Positives = 255/553 (46%), Gaps = 35/553 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGAAYVP++P++P R+ ++++D++P+ ++ + +P +
Sbjct: 2752 MVGLLGVLKAGAAYVPLDPAYPAERLAYMIEDSQPAALLTQRHLQEYL-PTLTLPLVLLD 2810
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ ++ + D P+ + L ++A V+YTSGSTG PKGV + + + N R
Sbjct: 2811 DDQRKTFTERDDNPV----VEALGVRNLAYVIYTSGSTGNPKGVMIEHRGLVNYSVDAAR 2866
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETT-RDPQKLVNIERLVLV 198
F S S+ + T L F SV EI+ LL G A L SRE + + I+ VL
Sbjct: 2867 LFGLSQSDTVLQQNT-LNFDLSVEEIFPALLAG-ATLTPSREIFGSEGTENHGIDPTVLH 2924
Query: 199 PTLLR--SILMYLALGP--ASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
T +++ P A + L+ ++L +G+ LS + + + +L N
Sbjct: 2925 LTAAHWHTLVAEWHKQPQVAEQRLQHVRLINVTGDALSAQKLKLWDEV--RPAHTRLINT 2982
Query: 255 YGSTEVMGDVT--YYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE T Y + + + IG+P+ N IYLLD P GE+++
Sbjct: 2983 YGPTEATVSCTAAYVSHDAAAGSEGSGNATIGKPMANTRIYLLDAHQQPVPYGVAGEIYI 3042
Query: 313 AGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
G +A GY+ A RF +P + P+ R+Y+TGD + G + Y GR D QVK
Sbjct: 3043 GGDGVARGYLNLEEVNAERFLADPFSESPD-ARMYKTGDLARYMADGRIEYLGRNDFQVK 3101
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++L E+E L GV + VV+ + G+ ++ +V +P ++ +A + +L
Sbjct: 3102 VRGFRIELGEIEARLGNCTGVKEAVVIAREDNPGDKRLVAYVVAQPQSQLTAADLRAELA 3161
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
L YM+P + ++ +PL N K+DR+ L A D D
Sbjct: 3162 PQLAEYMLPSAFVLLDELPLTPNRKLDRKAL--------------PAPDADALISRGYEA 3207
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
V + F+ELGG+SL ++ I +LR +G + + A
Sbjct: 3208 PQGETETQIVAIWQDLLGIEQVGRHDHFFELGGHSLLAVSLIERLRKQGLNLNVKTVFTA 3267
Query: 549 STLGEVLSKMSTD 561
T+ E+ +S D
Sbjct: 3268 PTVREMALAISQD 3280
Score = 174 bits (424), Expect = 7e-42
Identities = 133/451 (29%), Positives = 220/451 (48%), Gaps = 21/451 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGAAYVP++P++P R+ +++ D++P+ ++ + S +P +
Sbjct: 3839 MIGLLGVLKAGAAYVPLDPAYPAERLAYMITDSQPAALLTQRGLQERLPALS-MPLVLLD 3897
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + D P+ + L ++A V+YTSGSTG PKGV + + + N R
Sbjct: 3898 DEQYQGLAECDDNPV----VPTLGVRNLAYVIYTSGSTGNPKGVMIEHRGLVNYSVDAAR 3953
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETT-RDPQKLVNIERLVLV 198
F S S+ + T L F SV EI+ LL G A L SRE + + I+ VL
Sbjct: 3954 LFDLSQSDTVLQQNT-LNFDLSVEEIFPALLAG-ATLAPSREIFGSEGTETHGIQPTVLH 4011
Query: 199 PTLLR--SILMYLALGP--ASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
T +++ P A + L+ ++L +G+ LS + + + +L N
Sbjct: 4012 LTTAHWHTLVAEWHNQPQAAEQRLQHVRLINVTGDALSAQKLKLWDEV--RPAHTRLINT 4069
Query: 255 YGSTEVMGDVT--YYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE T Y + + + IG+P+ N IYLLD P GE+++
Sbjct: 4070 YGPTEATVSCTAAYVSYDAAAGSEGSGNATIGKPMANTRIYLLDAHQQPVPYGVAGEIYI 4129
Query: 313 AGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
G +A GY+ A RF +P + P+ R+Y+TGD + G + Y GR D QVK
Sbjct: 4130 GGDGVARGYLNLEEVNAERFLADPFSESPD-ARMYKTGDLARYMADGRIEYLGRNDFQVK 4188
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++L E+E L GV + VV+ + G ++ +V +P + +A + +L
Sbjct: 4189 VRGFRIELGEIEARLGNCKGVKEAVVIAREDNPGEKRLVAYVVAQPQTQITAAELRAELA 4248
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++ +PL N K+DR+ L
Sbjct: 4249 PQLAEYMLPSAFVLLDELPLTPNRKLDRKAL 4279
Score = 169 bits (410), Expect = 3e-40
Identities = 150/560 (26%), Positives = 255/560 (45%), Gaps = 42/560 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL K+GAAYVP++P+ P R+ +L+D++P ++ + + P +
Sbjct: 8130 IVGLLGVLKSGAAYVPIDPAHPADRMAFMLQDSQPRALLTQGALSLPV---GDTPLMLLD 8186
Query: 80 ELAQEATSHSADEPMDAETLAP-LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ E+ + D+ DA + LT++++A V+YTSGSTG KGV + + ++ N +W
Sbjct: 8187 --SAESLLAADDQAFDANPVVDGLTAENLAYVIYTSGSTGQSKGVMVEHRSVFN--FWNV 8242
Query: 139 --RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---E 193
RT V A F D + L G L+I+ + + +L++
Sbjct: 8243 LTRTTHQHCPTPATVALNAGFFFDMSIKGISQLFSGHKLVIIPQLLRANGSELLDFLEAH 8302
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
++ + + L+ G R + + GE ++ AS + K N + N
Sbjct: 8303 QVHAFDSTPSQLDTLLSAGLLERSSYQPVSVLLGGEAIN---ASTWEK-LRNCPTIRFYN 8358
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D T ++ DL IGRP+ N +++LD P GE+ +
Sbjct: 8359 MYGPTECTVDATIDLIR-----DLGEKPSIGRPIANVQVHVLDARGEPAPLGVAGEIHIG 8413
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G+ +A GY+ A RF +P + RLY+TGD G L G + Y GR D QVK+
Sbjct: 8414 GSGVARGYLNRDELSAERFIVDPFSDVAN-ARLYKTGDLGRWLADGTLEYMGRNDFQVKV 8472
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L VPG+ + +V+ +G+ + V G +A+H+ +L
Sbjct: 8473 RGFRIELGEIENVLLAVPGIREAIVIARNDSQGDSDSQRLVAYVCGESVAAEHLRSELLR 8532
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P ++++++PL NGK+DR+ L DA + +
Sbjct: 8533 HLPEYMVPSAFVQLDALPLTANGKLDRRAL------PAPGQDALASKAYEAPQGETEEAI 8586
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGA 548
+GR GF ELGG+SL ++ +++LR + G + + + A
Sbjct: 8587 AEIWKALLHLDQVGR--------NDGFLELGGHSLLAVQLLSRLRRKLGTRITLRELFDA 8638
Query: 549 STLGEVLSKMSTDPNGGADS 568
T+ + S ++ G A S
Sbjct: 8639 PTVLGLASLVNAAAPGEAQS 8658
>UniRef50_A1TW55 Cluster: Amino acid adenylation domain; n=1;
Acidovorax avenae subsp. citrulli AAC00-1|Rep: Amino
acid adenylation domain - Acidovorax avenae subsp.
citrulli (strain AAC00-1)
Length = 1449
Score = 209 bits (510), Expect = 2e-52
Identities = 149/446 (33%), Positives = 218/446 (48%), Gaps = 16/446 (3%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ AL+A ++GAAY+P++P FP R+ +L DA+P ++ + + G+
Sbjct: 525 VAALVAVLRSGAAYLPIDPDFPADRLAFMLDDAQPVCLMTTEELSGRF--DGGIA-RFIV 581
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A+ P A A L A V+YTSGSTG PKGV + +SAI NRL W
Sbjct: 582 DAAEPQAGIQPPAPAGALASATLHPSHPAYVIYTSGSTGRPKGVVVPHSAIVNRLRWMQA 641
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ S+ + + KT +F S E + PLL G L+I RDP L ++ V
Sbjct: 642 EYGLESSDRV-LQKTPSSFDVSAWEFFWPLLAGATLVIARPGGHRDPPYLADLIAREAVT 700
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T+ + S+L PA+ L+ VCSGE LS LA+ F G L N YG
Sbjct: 701 TVHFVPSMLELFLQEPAAAACHTLRRVVCSGEALSAPLAARFHGMLG---WCALHNLYGP 757
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT + L IPIGRP+ N +Y+LD L P GE+++AG L
Sbjct: 758 TEAAVDVTAWACTHEACAGL-ARIPIGRPIWNTRMYVLDPGLQPLPVGATGELYIAGDGL 816
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY+ A RF +P+ P R+YRTGD G + + GR+D QVKIRG R
Sbjct: 817 ALGYLNRPALTAERFIADPYG--PAGSRMYRTGDLARWCDDGTLEFLGRSDHQVKIRGLR 874
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++ E+E AL + PGV + V+ G+ ++ + G R + + +
Sbjct: 875 IEPGEIESALMRHPGVQQAAVVVREDAGGSKVLVAYCVPVAGDRLDDFSLRAHVAQRVPE 934
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + + +PL +GK+DR+ L
Sbjct: 935 YMVPSAFVVLAELPLGPSGKLDRRAL 960
>UniRef50_Q9HYR8 Cluster: Probable non-ribosomal peptide synthetase;
n=5; Pseudomonas aeruginosa|Rep: Probable non-ribosomal
peptide synthetase - Pseudomonas aeruginosa
Length = 2352
Score = 208 bits (509), Expect = 3e-52
Identities = 160/462 (34%), Positives = 233/462 (50%), Gaps = 41/462 (8%)
Query: 11 GPHFFYFSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKE 70
GPH + A+L +AG AYVP+ P P R+ +L+D +V+ D+ A
Sbjct: 506 GPHL-----LPAILGVQRAGGAYVPINPDHPLERVRLLLEDCGARVVLVDERAATLGESL 560
Query: 71 SGVPFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAI 130
E L Q + D P A +AP +A V+YTSGSTG+PKGV + + ++
Sbjct: 561 GETRVLHLERLPQS----TGDLP--AANVAP---GDLAYVIYTSGSTGMPKGVMVEHRSV 611
Query: 131 CNRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV 190
NRL W R +P + ++ + KT +TF SV E++ G L +L +DP++++
Sbjct: 612 VNRLNWMQRRYPIGE-RDVLLQKTPVTFDVSVWELFWWSFTGARLSLLPPGAEKDPREML 670
Query: 191 -NIER-----LVLVPTLLRSILMYLALGPASR-PLRRLKLWVCSGETLSKELASEFFKYF 243
+I+R + VP++L L L P +R L+L CSGE L+ + F + F
Sbjct: 671 RSIQRDAVTVIHFVPSMLTPFLDLLDGDPTARAAASSLRLVFCSGEALAPLQVARFRRLF 730
Query: 244 GNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPT-IPIGRPLDNCAIYLLDEELSPT 302
G D +L N YG TE DV+ + SD PT +PIGRP+DN +Y+LD L P
Sbjct: 731 G--DAVRLVNLYGPTEATVDVSDHEC-ASDN----PTRVPIGRPIDNLRLYVLDRALRPQ 783
Query: 303 RDSEPGEVWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVL 359
GE+++ G +A GY+ A RF +P RLYRTGD L G +
Sbjct: 784 PLGAVGELYIGGVGVARGYLNRPELNAERFLVDPFVAG---GRLYRTGDLARWLADGNLE 840
Query: 360 YAGRTDAQVKIRGHRVDLLEVERALAQVPGV-DKCVVLCYGLDRGNPEILGFVTTKPGAR 418
Y GR D QVKIRG+RV+ EV LA +PGV D VV RG ++G+ A
Sbjct: 841 YLGRADDQVKIRGNRVEPDEVRDRLAALPGVRDAAVVARDSAVRGT-HLVGYYVA--AAE 897
Query: 419 TSAQHIEGKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
+ L + L +M+P + ++S+PL NGK+DR+ L
Sbjct: 898 LDPGQLRAGLSATLPDFMLPAFFVRIDSLPLSANGKLDRRQL 939
Score = 155 bits (375), Expect = 6e-36
Identities = 158/529 (29%), Positives = 236/529 (44%), Gaps = 52/529 (9%)
Query: 28 KAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELAQEATS 87
+AG VP++ S+P R+ IL+ A+P V+ E +P EEL +
Sbjct: 1547 RAGLVCVPLDVSYPAQRLALILETAQPFRVVAHPEHAHVAAAERVLPV---EELVADI-- 1601
Query: 88 HSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSE 147
EP ET A D +A++L+TSGSTG PKGV LS+ N WQ R
Sbjct: 1602 ----EP---ETFAAPQLDELAMLLFTSGSTGRPKGVELSHRMWANYTQWQLRVASGVPGL 1654
Query: 148 EICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVPTLLRSILM 207
+ L+F + EI+ L G L ++S DP L+++ V +L +
Sbjct: 1655 RTLQF-APLSFDMAFQEIFSTLCGGGELQLISNRERMDPSALLHVLERRQVQRVLLPFVA 1713
Query: 208 YLALGPASRPL----RRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMGD 263
L AS L L++ V SGE L + + + G L N YG TE
Sbjct: 1714 LQRLAEASNALGVRPGALRVVVSSGEQL--RITEDVRAFCAAMPGLLLENQYGPTET-HQ 1770
Query: 264 VTYYVLEGSDQLDLYPTI-PIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYV 322
VTY+ L G YP + PIGRPLD + +LD L P GE++ G LA GY
Sbjct: 1771 VTYHSLSGDPA--HYPDLPPIGRPLDGVEVQVLDAALRPVPVGVTGELYFGGDCLARGYH 1828
Query: 323 GGG--GANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGHRVDLLE 379
A RF ++P +P RLYRTGD G ++ G +++ GR D QVK+RG R++ E
Sbjct: 1829 RAPKLTAERFVEHP--WRPG-ARLYRTGDLGRILGNGEIVWLGRADTQVKVRGFRIEPAE 1885
Query: 380 VERAL----AQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
VE A+ + PG+ V+ + + F+ +P A A+ ++ LRS L +
Sbjct: 1886 VELAIMRQAERQPGLRGAAVVARERQGNDAFLAAFLLGEPEAVDLAE-LKQALRSELPEH 1944
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P V+ L +GK D L + N + D
Sbjct: 1945 MVPAHFAWVDGFALTPSGKRDDAALRALPLEHGTNIEYLAPRD---------------DY 1989
Query: 495 XXTVGAVLGRAA-RGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
T+ +LG R + +R F++LGG SL+++ + + R Y V++
Sbjct: 1990 ERTLAGLLGELLDRPRVGIRDSFFDLGGTSLSAMRFMLLIEKR-YGVDL 2037
>UniRef50_Q47NS0 Cluster: Amino acid adenylation; n=1; Thermobifida
fusca YX|Rep: Amino acid adenylation - Thermobifida fusca
(strain YX)
Length = 1074
Score = 208 bits (509), Expect = 3e-52
Identities = 168/554 (30%), Positives = 252/554 (45%), Gaps = 35/554 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL +AGAAY+P++ P R+ +++ A V+ A P + +P
Sbjct: 517 VIALLGVLRAGAAYLPLDVDHPPARLAAMVERARAGTVVTCQGALPRLGDR--LPGTVVV 574
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A + EP+ + P D +A ++TSGSTG PKGV +++ AI NRL W
Sbjct: 575 DDAATRDRLAGLEPLPTRDVHP---DQLAYTIFTSGSTGEPKGVGVAHRAIANRLQWMQH 631
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
T+ + + + KT + F SV E + PL+ G L++ RDP L + E V
Sbjct: 632 TYRLTPEDRVAQ-KTPVGFDVSVWEFFWPLITGATLVVARPGGHRDPAYLAALFAEHKVT 690
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + S+L P +R L+ + SGE L +LA + + +L N YG
Sbjct: 691 VCHFVPSLLRVFLNEPTARRATALRQVIVSGEALDADLARAWARTLPQA---RLDNLYGP 747
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT + + G+ + +PIGRP+ N +Y+LD L P GE+++ G L
Sbjct: 748 TEAAVDVTSHPVCGAGTEPVRDPVPIGRPVWNTELYVLDSSLRPLPTGAVGELYLGGVQL 807
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHR 374
A GYVG G A+RF NP P RLYRTGD GAV Y GR D QVKI G R
Sbjct: 808 ARGYVGRPGMTASRFVANPFG--PPGSRLYRTGDLVRRRADGAVEYLGRVDDQVKINGVR 865
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+ EVE L PGV V G ++G++ G+ + L L
Sbjct: 866 VEPGEVEAVLRAQPGVADAAVAARPAPAGGLRLVGYL-VPDGSPPDVDEVRRGLADRLPA 924
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+P + V+++PL VNGK+ R L + D V+
Sbjct: 925 AWVPAAFVVVDALPLTVNGKLRRDAL-------PDPDPGPVS-------RRAPRTPLEHA 970
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
VLG A +S + F+ LGG+S++S+ + +L G ++ + D T
Sbjct: 971 LCAAFAEVLGMA---EVSADADFFALGGDSVSSLRLVGRLVREGIHLTVRDVFTYRTPER 1027
Query: 554 VLSKMSTDPNGGAD 567
+ + T P A+
Sbjct: 1028 LADAVPTTPPSEAE 1041
>UniRef50_Q5DIV7 Cluster: PvdI; n=5; Pseudomonas aeruginosa|Rep: PvdI
- Pseudomonas aeruginosa
Length = 5155
Score = 208 bits (509), Expect = 3e-52
Identities = 150/452 (33%), Positives = 230/452 (50%), Gaps = 40/452 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL+A KAG AYVP++P +P+ R ++L+D+ L++ + + GV +
Sbjct: 581 VVALMAILKAGGAYVPVDPEYPEERQAYMLEDSGVQLLLSQSHLKLPLAQ--GVQRIDLD 638
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +H+ + P L +++A V+YTSGSTG PKG +SA+ NRL W +
Sbjct: 639 QADAWLENHAENNPG-----VELNGENLAYVIYTSGSTGKPKGAGNRHSALSNRLCWMQQ 693
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
+ + + + KT +F SV E + PL+ G L++ + RDP KLV ++
Sbjct: 694 AYGLGVGDTV-LQKTPFSFDVSVWEFFWPLMSGARLVVAAPGDHRDPAKLVELINREGVD 752
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L++ L + + LK VCSGE L + + F Y N
Sbjct: 753 TLHFVPSMLQAFLQDEDVASCTS----LKRIVCSGEALPADAQQQVFAKLPQAGLY---N 805
Query: 254 FYGSTEVMGDVTYY--VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
YG TE DVT++ V EG D +PIGRP+ N A Y+LD L P GE++
Sbjct: 806 LYGPTEAAIDVTHWTCVEEGKD------AVPIGRPIANLACYILDGNLEPVPVGVLGELY 859
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+AG LA GY G A RF +P +R+YRTGD G + YAGR D QV
Sbjct: 860 LAGQGLARGYHQRPGLTAERFVASPFVAG---ERMYRTGDLARYRADGVIEYAGRIDHQV 916
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L E+E L + P V + VL +++G+V + + + L
Sbjct: 917 KLRGLRIELGEIEARLLEHPRVREAAVLAV----DGRQLVGYVVLESEGGDWREALAAHL 972
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
++L YM+P Q + +E +PL NGK+DR+ L
Sbjct: 973 ATSLPEYMVPAQWLALERMPLSPNGKLDRKAL 1004
Score = 205 bits (500), Expect = 4e-51
Identities = 152/452 (33%), Positives = 230/452 (50%), Gaps = 40/452 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL+A KAG AYVP++P +P+ R ++L+D+ L++ + + GV +
Sbjct: 3108 VVALMAILKAGGAYVPVDPEYPEERQAYMLEDSGVELLLSQSHLKLPLAQ--GVQRIDLD 3165
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A +S P D L +++A V+YTSGSTG PKG +SA+ NRL W +
Sbjct: 3166 RGAPWFEDYSEANP-DIH----LDGENLAYVIYTSGSTGKPKGAGNRHSALSNRLCWMQQ 3220
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+ + + + KT +F SV E + PL+ G L++ + RDP KLV ++
Sbjct: 3221 AYGLGVGDTV-LQKTPFSFDVSVWEFFWPLMSGARLVVAAPGDHRDPAKLVALINREGVD 3279
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L++ L + + LK VCSGE L + + F Y N
Sbjct: 3280 TLHFVPSMLQAFLQDEDVVSCTS----LKRIVCSGEALPADAQQQVFAKLPQAGLY---N 3332
Query: 254 FYGSTEVMGDVTYY--VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
YG TE DVT++ V EG D +PIGRP+ N A Y+LD L P GE++
Sbjct: 3333 LYGPTEAAIDVTHWTCVEEGKD------AVPIGRPIANLACYILDGNLEPVPVGVLGELY 3386
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+AG LA GY G A RF +P +R+YRTGD G + YAGR D QV
Sbjct: 3387 LAGQGLARGYHQRPGLTAERFVASPFVAG---ERMYRTGDLARYRADGVIEYAGRIDHQV 3443
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L E+E L + P V + VL +++G+V + + + + L
Sbjct: 3444 KLRGLRIELGEIEARLLEHPWVREAAVLAV----DGKQLVGYVVLESESGDWREALAAHL 3499
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
++L YM+P Q + +E +PL NGK+DR+ L
Sbjct: 3500 AASLPEYMVPAQWLALERMPLSPNGKLDRKAL 3531
Score = 144 bits (349), Expect = 8e-33
Identities = 137/456 (30%), Positives = 207/456 (45%), Gaps = 32/456 (7%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ LL KAGA Y+P++P++P R+ ++L+D+ +I ++ + + P A
Sbjct: 2055 FDLVVGLLGILKAGAGYLPLDPNYPAERLAYMLRDSGARWLISQET----LAERLPCP-A 2109
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
E L E + A D L + +++A V+YTSGSTG PKGV +S +A+
Sbjct: 2110 EVERLPLETAAWPASA--DTRPLPEVAGETLAYVIYTSGSTGQPKGVAVSQAALVAHCQA 2167
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCE-IWGPLLHGRALLILSRETTRDPQKLVN-IER 194
RT+ + C + A D+ E ++ PLL G A ++L Q L + +ER
Sbjct: 2168 AARTYGVGPGD--CQLQFASISFDAAAEQLFVPLLAG-ARVLLGDAGQWSAQHLADEVER 2224
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVC--SGETLSKELASEFFKYFGNEDGYKLA 252
+ L + RR+ + C GE L ++ + E +
Sbjct: 2225 HAVTILDLPPAYLQQQAEELRHAGRRIAVRACILGGEAWDASLLTQ--QAVQAEAWF--- 2279
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE + +T Q P I GR L +LD L P GE+++
Sbjct: 2280 NAYGPTEAV--ITPLAWHCRTQEGGAPAI--GRALGARRACILDAALQPCAPGMIGELYI 2335
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
G LA GY+G G A RF +P + E RLYRTGD V G V Y GR D Q+K
Sbjct: 2336 GGQCLARGYLGRPGQTAERFVADPFSGSGE--RLYRTGDLARYRVDGQVEYLGRADQQIK 2393
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS--AQHIEGK 427
IRG R+++ E+E L P V + V+ G P + ++ + R +
Sbjct: 2394 IRGFRIEIGEIESQLLAHPYVAEAAVVAQD-GVGGPLLAAYLVGRDAMRGEDLLAELRTW 2452
Query: 428 LRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKM 462
L L YM P +V S+PL NGK+DR+ L K+
Sbjct: 2453 LAGRLPAYMQPTAWQVLSSLPLNANGKLDRKALPKV 2488
Score = 135 bits (327), Expect = 4e-30
Identities = 130/458 (28%), Positives = 211/458 (46%), Gaps = 36/458 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA KAG AYVP++ +P+ R+ ++++D+ L++ + G+ S +
Sbjct: 4607 MVAFLAVLKAGGAYVPLDIEYPRERLLYMMQDSRAHLLLTHSHLLERLPIPEGLSCLSVD 4666
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+E A +P A L D++A V+YTSGSTG+PKGV +S+ + +
Sbjct: 4667 R-EEEWAGFPAHDPEVA-----LHGDNLAYVIYTSGSTGMPKGVAVSHGPLIAHIVATGE 4720
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRETTRDPQKLVNIERL--- 195
Y + E C D E W PL++G +LI + + R
Sbjct: 4721 R--YEMTPEDCELHFMSFAFDGSHEGWMHPLINGARVLIRDDSLWLPERTYAEMHRHGVT 4778
Query: 196 --VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V P L+ + + P+R ++ G+ +++ AS + + Y L N
Sbjct: 4779 VGVFPPVYLQQLAEHAERDGNPPPVR---VYCFGGDAVAQ--ASYDLAWRALKPKY-LFN 4832
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + + D +PIG L N + Y+LD +L+ GE+++
Sbjct: 4833 GYGPTETVVTPLLWKARAGDACGA-AYMPIGTLLGNRSGYILDGQLNLLPVGVAGELYLG 4891
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ A RF +P RLYR+GD G V Y GR D QVKI
Sbjct: 4892 GEGVARGYLERPALTAERFVPDPFGAPGS--RLYRSGDLTRGRADGVVDYLGRVDHQVKI 4949
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK-------PGARTSAQ- 422
RG R++L E+E L + P V + VV+ G +++G+V + P A+ +
Sbjct: 4950 RGFRIELGEIEARLREHPAVREAVVVAQPGAVGQ-QLVGYVVAQEPAVADSPEAQAECRA 5008
Query: 423 HIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
++ LR L YM+P ++ + +PL NGK+DR+GL
Sbjct: 5009 QLKTALRERLPEYMVPSHLLFLARMPLTPNGKLDRKGL 5046
>UniRef50_UPI0000510064 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1;
Brevibacterium linens BL2|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins -
Brevibacterium linens BL2
Length = 1316
Score = 208 bits (508), Expect = 4e-52
Identities = 155/451 (34%), Positives = 219/451 (48%), Gaps = 27/451 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+M+LLAT +GAAYVP+EPS P R+ ++ D +P+LVI D +P+ P
Sbjct: 528 VMSLLATSLSGAAYVPLEPSLPVTRLDSMISDVDPALVITGDGKEPAPGGGDTRPTLQLR 587
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + A +P + P T+D A V++TSGSTG PKG +S+ AI NRL W
Sbjct: 588 EDTLDCLRDLAADPANPTPPMPPTADDTAYVIFTSGSTGAPKGTAVSHRAIVNRLVWMQH 647
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ D+ +I + KT +F SV E + PL+ G + + E +DP+ L V
Sbjct: 648 EYRL-DATDIVLQKTPFSFDVSVWEFFWPLISGAVIAVAEPEIHKDPEALARTIAANGVT 706
Query: 200 T--LLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T + S L L+ CSGE L E A E L N YG
Sbjct: 707 TCHFVPSALSVFTGAHQVEHCTSLRRVFCSGEALDAETAHRLLAALPVE----LHNLYGP 762
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ + G+D +PIGRP+ N Y+LD G + +AG L
Sbjct: 763 TEAAVDVTHWTV-GADHSG---PVPIGRPVWNTRTYVLDSLGRLLPPGAAGHLHLAGVQL 818
Query: 318 AAGYVGGG--GANRFCDNPHATQP--EFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
GYVG A +F +P ++ +R+Y TGD GA+ Y GR D QVKIRG
Sbjct: 819 GQGYVGRPELTAEKFFTHPGLSRALGRRERVYATGDIARWRSDGALDYLGRIDDQVKIRG 878
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK---LR 429
R++L E+E LA+ P V + VV+ +G + G+V + SA +I G L
Sbjct: 879 LRIELGEIESVLAEHPDVHRAVVVPHGAGTA-ASLRGYV------QASANNINGLRDWLV 931
Query: 430 SALTHYMMPQVIE-VESIPLLVNGKVDRQGL 459
L YM+P + V +P+ NGK+DRQ L
Sbjct: 932 DRLPDYMVPSTLTCVGELPMTANGKLDRQRL 962
>UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Nocardia farcinica|Rep: Putative non-ribosomal
peptide synthetase - Nocardia farcinica
Length = 5961
Score = 208 bits (508), Expect = 4e-52
Identities = 153/454 (33%), Positives = 224/454 (49%), Gaps = 36/454 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A AG AYVP++P P R HIL A P+ V+ S + P +
Sbjct: 592 VIAMYAVLSAGGAYVPLDPDHPAERTAHILATAAPACVLTAGETRLS----ADAPVVHLD 647
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L + ++H D E PL + A V++TSGSTG PKGV +++ AI NRL W +
Sbjct: 648 DL--DLSAHPDGPVWDRERRRPLRPRNPAYVIFTSGSTGAPKGVAVTHEAIVNRLVWMQQ 705
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VNIE 193
T+ E+ + KT TF SV E + PL G L++ + + RDP L +
Sbjct: 706 TYRLGPG-EVVLQKTPATFDVSVWEFFWPLQVGAELVLAAPDGHRDPAYLRRVIDDYGVT 764
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VP++L + L + A LRR+ SGE L A G +L N
Sbjct: 765 TAHFVPSMLEAFLAGQDIARAG-TLRRV---FASGEALPAATAQRLRLL----TGARLHN 816
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ + +D +PIG P+ N +++LD L P PGE++++
Sbjct: 817 LYGPTEAAVDVTFHEVTDADT----DAVPIGAPVFNTRLHVLDSRLRPVPVGAPGELYLS 872
Query: 314 GANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G LA GYV G A RF +P P R+YRTGD G + Y GRTD QVK+
Sbjct: 873 GVQLARGYVARPGLSAERFVADPFG--PAGTRMYRTGDLVRWNTSGELEYLGRTDFQVKL 930
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNP----EILGFVTTKPGARTSAQHIEG 426
RG R++L E+E LA V GV + VVL D G+P +++ +V A+ +
Sbjct: 931 RGLRIELGEIEAVLAGVDGVVRAVVLVRD-DVGSPALGEQLVAYVVAAEPDAVGAEQLRA 989
Query: 427 KLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
AL YM+P + ++ +P+ +GK+DR L
Sbjct: 990 AALRALPAYMVPAAYVVLDELPVNASGKLDRAAL 1023
Score = 202 bits (493), Expect = 3e-50
Identities = 144/446 (32%), Positives = 220/446 (49%), Gaps = 30/446 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A AG AYVP++P+ P R+ HIL A P V+ + + +G +
Sbjct: 2717 VVGMYAVLAAGGAYVPLDPAHPAERLAHILDTARPVCVL---TRGRDGLEVTGPAVLDLD 2773
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + T + DA+ APL A VL+TSGSTG PKGV + ++AI NRL W
Sbjct: 2774 LL--DTTGYPDTALTDADRRAPLRPARPAYVLFTSGSTGRPKGVTIEHAAIVNRLRWMQD 2831
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ D+ ++ + KT +TF SV E + PL G L++ + RDP+ L + V
Sbjct: 2832 EYRI-DARDVVLQKTPVTFDVSVWEFFWPLQVGARLVLARPDGHRDPRYLAELITAEAVT 2890
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + ++L PA+ L+ CSGE L A G + N YG
Sbjct: 2891 VAHFVPAMLAVFVAEPAAAQCHSLRAVFCSGEALPPAPAHRLRAL----TGAAVHNLYGP 2946
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ + +D ++PIG P+ N +Y+LD+ L P PGE+++AG L
Sbjct: 2947 TEAAVDVTHHEVTDADT----QSVPIGSPVANTRVYVLDDRLRPVPAGVPGELYLAGVQL 3002
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHR 374
A GY G A+RF +P R+YRTGD G + Y GRTD QVK+RG R
Sbjct: 3003 ARGYAGRPDLTADRFVADPFTPG---ARMYRTGDRVRWSAAGELEYLGRTDFQVKVRGMR 3059
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++ E+E AL ++ GVD+ VV+ + ++ ++ P + L L
Sbjct: 3060 IEPGEIEAALTELDGVDQAVVVA-----RDEHLVAYLI--PAGPVDPDAVRVALARRLPA 3112
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGL 459
Y++P + +++ PL +GK+DR L
Sbjct: 3113 YLVPAAFVLLDAFPLNASGKLDRTAL 3138
Score = 193 bits (471), Expect = 1e-47
Identities = 137/450 (30%), Positives = 220/450 (48%), Gaps = 25/450 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKE-SGVPFASF 78
++ALLA KAG Y+P++P +P RI +++ DA P + + ++ ++ G P
Sbjct: 3777 VVALLAVLKAGGGYLPIDPDYPADRIEYMIDDARPICAL--TAPGTALARDWFGGPVLDV 3834
Query: 79 EELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E A + A P+ DA+ APL + A V+YTSGSTG PKGV + + + L
Sbjct: 3835 ERDAD--PRYYASTPLTDADRRAPLRPEHTAYVIYTSGSTGRPKGVVIPHRNVVRLLDNT 3892
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ER 194
F + ++ + F SV E+WG LLHG +++++ T+R P++ + ER
Sbjct: 3893 RELFGFG-PHDVWTMFHSYAFDFSVWELWGALLHGGSVVVVDYFTSRSPEQFRELLVGER 3951
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVC-SGETLSKELASEFFKYFGNEDGYKLAN 253
+ ++ + +A A+ P WV GE L + + + + D +L N
Sbjct: 3952 VTVLDQTPSAFYQLVAADTAAEPAEYALRWVIFGGEALEPQRLGGWLRRY--PDAPRLVN 4009
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE V+Y ++ IG + + +LD L P PGE++V+
Sbjct: 4010 MYGITETTVHVSYRAIDAGTG----AASVIGGAIPGLTVRVLDPRLRPVPVGVPGEIYVS 4065
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY+G G A RF +P+ P R YR+GD G + + GR D QV +
Sbjct: 4066 GGQLARGYLGRPGLTAGRFVADPYG--PAGARAYRSGDLARWTATGELEFLGRADQQVNL 4123
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E AL P V + V+ I+G++ T T+ + ++R
Sbjct: 4124 RGFRIELGEIEAALLAEPEVTEAAVVVRSDLVDEARIVGYLVTAGPVDTA--ELRERVRR 4181
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +M+P ++E++ IPL VNGK+DR L
Sbjct: 4182 TLPEHMVPAALVEIDRIPLTVNGKLDRAAL 4211
Score = 186 bits (452), Expect = 3e-45
Identities = 157/521 (30%), Positives = 239/521 (45%), Gaps = 38/521 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+ A KAGAA+VP++P++P RI H+L+D+ L + + + +
Sbjct: 1658 VTAVWAIAKAGAAWVPVDPAYPAERIEHMLRDSGAVLGLTVGAVRADLPGQPHWLVLDDV 1717
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E E + DAE + PL ++A V+YTSGSTG PKGV ++ + + Q
Sbjct: 1718 EFGFECARFGGEPVRDAERVRPLRPHNLAYVIYTSGSTGTPKGVLVTQAGVAGFAAEQTA 1777
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+P + + + + +F +V E+ A L+++ E R ++LV + V
Sbjct: 1778 RYPIDATARV-LHVGSPSFDITVAELL-MAFDSAATLVIAPEEARFGRELVELLAAQRVT 1835
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + L + PA P L++ V GE EL + + G +L + YG TE
Sbjct: 1836 HSIMTPSGALTIDPAEVP--DLRVLVAGGEACPPELVRRW-----HAAGRRLVDAYGPTE 1888
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
++ SD+L+ + IGRPL ++LDE L P GE++VAGA LA
Sbjct: 1889 AT-----VAVDISDRLEPGRPVTIGRPLRGVREWVLDERLRPVPVGVAGELYVAGAQLAR 1943
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF--GTLVKGA--VLYAGRTDAQVKIRGH 373
GY G A RF P A +R+YRTGD TL G + Y GR DAQVK+RG
Sbjct: 1944 GYHGRRATTAERFVACPWAPG---ERMYRTGDLVRWTLASGGRELEYLGRNDAQVKVRGF 2000
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E ALA PGV VV + ++ +V G A ++ LR+ L
Sbjct: 2001 RIELGEIEAALAARPGVAHAVVTVHRDPARGDQLAAYVVPSGGHPLDAGDLKAGLRTRLA 2060
Query: 434 HYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
+++P I V +++PL NGK+DR L A +
Sbjct: 2061 PHLVPAAITVLDTLPLTPNGKLDRAAL--------------PAPEFGVRAYRAPATDVER 2106
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL 533
T VLG A + F+ELGGNSL + + +L
Sbjct: 2107 TVAATYAEVLGVRAEPGVGRDDDFFELGGNSLIATRLVARL 2147
Score = 180 bits (439), Expect = 1e-43
Identities = 128/382 (33%), Positives = 191/382 (50%), Gaps = 23/382 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A +AG AYVP++P P RI HIL A P V+ A + ++ +P +
Sbjct: 4842 VVAMHAVVRAGGAYVPVDPDHPAERIAHILDTAAPVCVL----ATGDLPFDTALPVLDID 4897
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A D+P+ D E + PL + A V++TSGSTG PKGV + ++A+ N++ W
Sbjct: 4898 GGAA-----LPDDPIRDEERVRPLRPEHPAYVIFTSGSTGRPKGVAVPHAAVANQIRWLC 4952
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVL 197
F S + C+ KT TF SV E WGPLL G L++ + RDP +L + ++R +
Sbjct: 4953 AEFGLG-SADACLLKTPATFDLSVWEFWGPLLSGGRLVVTAPGDERDPDRLRDLLDRHAI 5011
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
++ + LG A+ L+ + GE L +A++F G L N YG
Sbjct: 5012 TLLCTVPSMLAMLLGAAAGLPGALRHVLAIGEALPPAVAADFLDRAAG-TGAALHNLYGP 5070
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE +T + + + T+PIG P N +Y+LD + P GE+++AG L
Sbjct: 5071 TEAAVSITAHEVRERPR----HTVPIGTPAWNSRLYVLDRRMRPVPVGVAGELYLAGVQL 5126
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHR 374
A GY A RF +P R+YRTGD G++ Y R D QVKI G R
Sbjct: 5127 ARGYQAAPALTAGRFVADPF---DRGARMYRTGDIVRRRADGSLEYLERADFQVKIGGFR 5183
Query: 375 VDLLEVERALAQVPGVDKCVVL 396
++L ++E AL +PGV V L
Sbjct: 5184 IELGDIESALLALPGVRAAVAL 5205
>UniRef50_A0UVH3 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 2006
Score = 208 bits (508), Expect = 4e-52
Identities = 160/553 (28%), Positives = 270/553 (48%), Gaps = 46/553 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+AL KAG AY+P + P+ R+T +L+DA+ +++ + ++ K+ +
Sbjct: 567 IALEGILKAGGAYLPFDTDCPKERLTFMLEDAQVPILVTQERHIEAL-KDINTIKICIDA 625
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
E + S + P++ ++ +++A V+YTSGSTG PKG +L + A+ NR+ W
Sbjct: 626 NYNEISKESIENPVNIASM-----NNLAYVIYTSGSTGKPKGAKLPHLALFNRIKWAQGN 680
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV-- 196
+ + ++ + + KT +TF SV E + PL G L++ +D LV++ E+ V
Sbjct: 681 YKLNATDRV-LQKTPMTFDVSVWEYFWPLAVGAGLVMARPGGHKDSAYLVDVISEKKVTT 739
Query: 197 --LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
VP++LR+ L + A+ LRR+ + GE LS EL FF+ E L N
Sbjct: 740 IQFVPSMLRAFLEENEIKKANC-LRRV---ISGGEALSVELHDRFFEKLDVE----LHNQ 791
Query: 255 YGSTEVMGDVTYY-VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVTY+ +G + TIPIG PL N +Y+LD+ +P PGE+ +
Sbjct: 792 YGPTEAAIDVTYWKCYKGCKR----HTIPIGHPLANTKLYILDKYFNPVPIGVPGELHIC 847
Query: 314 GANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKI 370
G LA+GY+ +F NP + + RLY+TGD G++ + GR D QVKI
Sbjct: 848 GDGLASGYLNRPELTNEKFISNPFSDK-HGGRLYKTGDLVRYANDGSIEFIGRIDHQVKI 906
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L Q P V V+ + ++ ++ + G + + L++
Sbjct: 907 RGLRIELGEIEAMLLQHPDVHASAVIVWEGSEDVKRLVAYIVMESGKEFNTTELRSYLKA 966
Query: 431 ALTHYMMPQVI-EVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P V+ ++++PL +GK+D++GL AVD
Sbjct: 967 KLPDYMVPAVLMNIDALPLTTSGKLDKRGL--------------PAVDFSRDMMEQPFAA 1012
Query: 490 XXXXXXXTVGAVLGRAAR-GTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
T+ + + + + F+ELGG+S+ SI + + R G Y+
Sbjct: 1013 PRNHVEETLAGIWADILKLEEVGIHDRFFELGGDSILSIQVVARARQSGIYITPKQIFEH 1072
Query: 549 STLGEVLSKMSTD 561
T+ E+ ++T+
Sbjct: 1073 QTIEELAQVVNTE 1085
>UniRef50_P29698 Cluster: Enterobactin synthetase component F; n=32;
Enterobacteriaceae|Rep: Enterobactin synthetase
component F - Shigella flexneri
Length = 1281
Score = 208 bits (508), Expect = 4e-52
Identities = 148/459 (32%), Positives = 235/459 (51%), Gaps = 40/459 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+AL A +AGAA++P++ +P R+ +L+DA PSL+I D P S VP
Sbjct: 524 LALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF---SDVP------ 574
Query: 81 LAQEATSHSADEPMDAETLAPLTSDS---IAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
T+ + P+ + APL A +++TSGSTG PKGV + +AI NRL W
Sbjct: 575 ---NLTNLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRLLWM 631
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VN 191
+P + E++ KT +F SV E + P + G L++ E RDP +
Sbjct: 632 QNHYPLT-GEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFFAEYG 690
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ VP++L + + L A + LK CSGE L +L E+ + G L
Sbjct: 691 VTTTHFVPSMLAAFVASLTPQTARQSCVTLKQVFCSGEALPADLCREWQQL----TGAPL 746
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLY-PTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
N YG TE DV++Y G + + ++PIG P+ N + +LD + P G++
Sbjct: 747 HNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGVAGDL 806
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQ 367
++ G LA GY+G A+RF +P A +R+YRTGD L GAV Y GR+D Q
Sbjct: 807 YLTGIQLAQGYLGRPDLTASRFIADPFAPG---ERMYRTGDVARWLDNGAVEYLGRSDDQ 863
Query: 368 VKIRGHRVDLLEVERALAQVPGVDK-----CVVLCYGLDRGNP-EILGFVTTKPGARTSA 421
+KIRG R++L E++R + +P V + CV+ G+ +++G++ ++ G
Sbjct: 864 LKIRGQRIELGEIDRVMQALPDVKQAVTHACVINQAAATGGDARQLVGYLVSQSGLPLDT 923
Query: 422 QHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
++ +LR L +M+P V +++ +PL NGK+DR+ L
Sbjct: 924 SALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKAL 962
>UniRef50_A1FGJ5 Cluster: Amino acid adenylation; n=1; Pseudomonas
putida W619|Rep: Amino acid adenylation - Pseudomonas
putida W619
Length = 2137
Score = 208 bits (507), Expect = 6e-52
Identities = 162/457 (35%), Positives = 237/457 (51%), Gaps = 34/457 (7%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F+ I+ LLA KAG AYVP++P+ P R+ +++D+ +++ P + E +
Sbjct: 1591 FAMIVGLLAILKAGGAYVPLDPAHPAERLAFVVRDSGIKVLL----DQPGLLAELP-EYD 1645
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTS-DSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
L EA D+P+D AP +S D++A ++YTSGSTG+PKG LS +
Sbjct: 1646 GLLRLNLEAGYD--DQPVDNP--APRSSVDNLAYIIYTSGSTGLPKGTLLSQHNVLRLFS 1701
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--- 192
R F + D ++ + F SV EI+G LLHG L+I+ + +RDPQ + +
Sbjct: 1702 ACDRWFRF-DHNDVWTLFHSFAFDFSVWEIFGALLHGGRLVIVPQTLSRDPQGFLQLLVD 1760
Query: 193 ERLVLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
ER+ ++ P+ + L A S L L+L + GE L +F+ FG +
Sbjct: 1761 ERVSVLNQTPSAFKP-LTQAACSATSADLA-LRLVIFGGEALDVAALRPWFERFGAQRP- 1817
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTI-PIGRPLDNCAIYLLDEELSPTRDSEPG 308
+L N YG TE VTY + G D DL T+ PIG +D+ + YLLD EL P G
Sbjct: 1818 QLVNMYGITETTVHVTYRPI-GLD--DLSRTVSPIGELIDDLSGYLLDGELEPVPAGCVG 1874
Query: 309 EVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTD 365
E+++ A LA GY+ G A RF NP +TQP RLYRTGD G + Y GR D
Sbjct: 1875 ELYIGQAGLARGYLNRAGLSATRFIANPFSTQPG-SRLYRTGDLARRRGDGTLEYIGRID 1933
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRG--NPEILGFVTTKPGARTSAQH 423
QVK+RG R++L EVE +L P V + VV+ D+G +L ++ G
Sbjct: 1934 QQVKVRGFRIELGEVEASLLAQPAVAQAVVIA---DQGPAGTRLLAYLVAHEGQGGDTGA 1990
Query: 424 IEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L++ L YM+P + +E +PL VNGK+DR L
Sbjct: 1991 LRAALKAQLPDYMVPAHCMWLEQLPLTVNGKLDRSAL 2027
Score = 157 bits (382), Expect = 8e-37
Identities = 138/450 (30%), Positives = 215/450 (47%), Gaps = 32/450 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLAT KAGAAYVP++P FP R+ ++L+D L++ S ++ G +
Sbjct: 555 IVALLATLKAGAAYVPLDPQFPAERLAYMLEDCGAPLLLSQASVLAAL-PTPGQQVLLLD 613
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + T+H EP A P +A VLYTSGSTG PKGV + + A+ N + +
Sbjct: 614 DFDLQ-TAHQ-PEPALALDCPP---QQLAYVLYTSGSTGNPKGVMVPHGALSNFVAAMAK 668
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLV 196
P + + T +F E++ PL G +++ + T +DP ++++ E +
Sbjct: 669 A-PGLHPGQRLLSITTCSFDIFGLELYLPLCTGACMVLADKHTVQDPAAILDLLISEHID 727
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
++ + M L P R L L +C GE L +LA L N YG
Sbjct: 728 VLQATPSTWRMLLDNDPDQR-LPALTA-LCGGEALGDDLAVRLLARCA-----ALWNLYG 780
Query: 257 STE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE + + + S + +L G+P++ + LLD L P+ ++++ G
Sbjct: 781 PTETTIWSARHALARASARPEL------GQPIERTGLLLLDGNLLPSPPGVAADLYIGGD 834
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
LA GY G A RF +P+ E RLYRTGD G++ + GR D QVKIRG
Sbjct: 835 GLAQGYHQRPGLTAERFVPHPYGKPGE--RLYRTGDLARRHASGSLDFLGRVDHQVKIRG 892
Query: 373 HRVDLLEVERALAQVPGV-DKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIEGKLRS 430
R++L E+E AL + V + VV G+D ++P + H LR
Sbjct: 893 FRIELGEIESALLTLDAVREAAVVARDGVDGAQLVAYVVPASRPADIQAFTAHCLAPLRE 952
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGL 459
L YM+P + ++++PL NGK+DR+ L
Sbjct: 953 QLPGYMLPARLHLLQAMPLTPNGKLDRKAL 982
>UniRef50_UPI00004DBA5D Cluster: UPI00004DBA5D related cluster; n=2;
Xenopus tropicalis|Rep: UPI00004DBA5D UniRef100 entry -
Xenopus tropicalis
Length = 1859
Score = 206 bits (504), Expect = 1e-51
Identities = 152/454 (33%), Positives = 232/454 (51%), Gaps = 32/454 (7%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+AL+A +AGAAY+P++ +P R+ IL+DA P ++I SA+ + F F+
Sbjct: 1075 LALMAVIEAGAAYLPLDLGYPDERLKFILEDAAPQILI-TTSAERARFGHGTTQVLEFDR 1133
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
L + T P+ + LT + A ++YTSG+TG PKG +S+ AI NR+ W
Sbjct: 1134 LRPDITP----PPL----VVALTPEHPAYLIYTSGTTGRPKGALVSHRAIVNRILWMQHE 1185
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VNIER 194
+P + + ++ + KT F SV E + PL+ G L++ + +DP L +
Sbjct: 1186 YPLTPA-DVVLQKTPCGFDVSVWEFFWPLMVGARLVMAAPGVHQDPLALRQTMADYGVSC 1244
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
L VP++L L L+L CSGE LSK LA EF + +L N
Sbjct: 1245 LHFVPSMLALFTESLRNDKGVDLSPALRLVFCSGEALSKPLAREFGECL---PAARLHNL 1301
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE DV+Y G D + P +PIGRP+ N + +LD L P GE+++AG
Sbjct: 1302 YGPTEAAVDVSYRPAFG-DLGEGGPGVPIGRPVWNTRLRVLDAWLRPVPVGACGELYLAG 1360
Query: 315 ANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIR 371
LA GY+G G A RF +P+ + +R+YRTGD L G V Y GR D Q+KIR
Sbjct: 1361 EQLALGYLGRPGLSATRFVADPYGSG---ERMYRTGDVVRWLSSGEVEYLGRADDQLKIR 1417
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRG-----NPEILGFVTTKPGARTSAQHIEG 426
G R++L E+E L +V G+ V L N +++ +V G + +
Sbjct: 1418 GQRIELGEIEARLREVTGIANAAVHALELAGASGVGDNRQLVAYVVAAEGHTLDPEALRV 1477
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L ++L +M+P +E+ ++PL NGK++R+ L
Sbjct: 1478 GLLASLPAHMVPVAYVELAALPLSPNGKLNRKAL 1511
Score = 64.1 bits (149), Expect = 1e-08
Identities = 39/106 (36%), Positives = 60/106 (56%), Gaps = 8/106 (7%)
Query: 360 YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART 419
+ GR D QVKIRG+RV+L +VE AL+ +PGV+ + L ++ +LG+ PG
Sbjct: 366 FLGRADDQVKIRGYRVELSDVENALSLLPGVESALALAESVN-DTQRLLGYCAV-PGLNP 423
Query: 420 SAQH-----IEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
AQ + LR L YM+P + V ++ P ++GK+DR+ L
Sbjct: 424 QAQDKHAHTLLATLRQRLPDYMVPAALVVLDAFPRNLSGKIDRKRL 469
Score = 54.4 bits (125), Expect = 1e-05
Identities = 32/113 (28%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL +GA +P++ P R+ + +DA P V+ + + +G+ + +
Sbjct: 203 LVALLGVMASGATLLPLDLDCPAERVAMMCEDAHPMAVL--SGTEVATVFPAGLTRINLD 260
Query: 80 EL-AQEATSHSADEPMD-AETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAI 130
+ Q A + +D P++ E P ++IA +++TSGSTG PKGV +++A+
Sbjct: 261 QAHVQIALAGFSDAPLEPTEGFGPPGPEAIAYIIFTSGSTGRPKGVMNTHAAL 313
>UniRef50_Q2SGN2 Cluster: Non-ribosomal peptide synthetase modules and
related protein; n=1; Hahella chejuensis KCTC 2396|Rep:
Non-ribosomal peptide synthetase modules and related
protein - Hahella chejuensis (strain KCTC 2396)
Length = 2159
Score = 206 bits (504), Expect = 1e-51
Identities = 153/468 (32%), Positives = 234/468 (50%), Gaps = 42/468 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAGAAY P++P +P R+ ++L+DA P V+ P+ +A
Sbjct: 1186 VVALLAVLKAGAAYAPLDPHYPGDRLDYMLRDAAPKAVLTHAQV-PADVNALLAAYAVER 1244
Query: 80 EL------AQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
E A A H + E A + + +A V+YTSGSTG PKGV + + NR
Sbjct: 1245 EARLIDLNATAAWEHKRSVDLSREETA-VNASHLAYVIYTSGSTGRPKGVMNEHRGVVNR 1303
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
L W + + +E+ + KT +F SV E + PL++G L++ E +DP L ++
Sbjct: 1304 LTWMQKAHALT-AEDAVLQKTPFSFDVSVWEFFWPLMYGARLVVAKPEGHKDPVYLSDLI 1362
Query: 194 R------LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
R L VP++L L A G S LR + CSGE L + F + F
Sbjct: 1363 RARRVTTLHFVPSMLSPFLDQAAAG-VSDSLRHV---FCSGEALPAQSVRRFRERF---P 1415
Query: 248 GYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP 307
G +L N YG TE DVT + G++ + T+PIGRP+DN +Y+LD P
Sbjct: 1416 GVELYNLYGPTEAAIDVTVWDCVGNE---VGATVPIGRPIDNIRLYILDPHRQPCPVGVV 1472
Query: 308 GEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRT 364
GE+++AG +A GY+ A +F +P + +YRTGD L G + Y GR
Sbjct: 1473 GELYIAGVGVARGYLNQPELTAEKFVADPFCADGG-RAMYRTGDLARFLPNGDIEYLGRN 1531
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQH 423
D QVK+RG R++L EVE A+A V +CV L G+ ++ +VT P A + +
Sbjct: 1532 DFQVKLRGFRIELGEVEAAIASHASVRECVALVREDAPGDARLVAYVTAAPSLALANGED 1591
Query: 424 IEGK-----------LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
++ + L+ L +M+P + + ++P+ NGK+DR+ L
Sbjct: 1592 VDAQADALNLALREHLQDRLPAFMIPSNFVWLATMPVTSNGKLDRKAL 1639
Score = 180 bits (437), Expect = 2e-43
Identities = 172/574 (29%), Positives = 268/574 (46%), Gaps = 48/574 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+L KAGAAY P++ S+P R +IL+D+ S+VI SA+ + + FA +
Sbjct: 91 IVAVLGALKAGAAYAPVDMSYPLERQAYILRDSNVSVVI--SSAE--IIRALPDTFAFLD 146
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + + + D+ + A T + +A ++YTSGSTG PKGV + + A+ N L WQ R
Sbjct: 147 MDAYDFSGDANDDESQNPSRA-CTPEDLAYLIYTSGSTGAPKGVCMPHKALVNLLVWQIR 205
Query: 140 -TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-----E 193
Y+ + + + L+F S EI+ L G L++++ E DP L+++
Sbjct: 206 EQGDYAGKKTLQF--SPLSFDVSFQEIFATLASGGELVLMANELRLDPLALLSLIESQQA 263
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ + +P + + L A+ P L + V +GE L + ++F +L N
Sbjct: 264 QRIFLPYVALNSLALAAVAEDRYPGGLLDV-VTAGEQL--VITPAIRQFFSALPNCRLHN 320
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIP-IGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG +E VT + L G + +P +P +G P+D +++LDE P RD PGE+ +
Sbjct: 321 HYGPSE-SHVVTAHTLSGHPR--QWPDLPSVGAPIDQVELFVLDENNRPLRDETPGELCI 377
Query: 313 AGANLAAGY--VGGGGANRFCD-NPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQV 368
G LA GY A RF D + P +RLYRTGD +L GR D QV
Sbjct: 378 GGLQLAYGYHQRPQETAARFVDIDVDGGGP--RRLYRTGDLARWRPDGLLDILGRIDFQV 435
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA--RTSAQHIEG 426
KIRG+RV+L EVE L + P V VV G D + + FV A R +++ ++
Sbjct: 436 KIRGYRVELGEVEAMLMRHPAVRDAVVAAQGEDADSKCLAAFVLVSERAQQRQTSEGVQE 495
Query: 427 KLRSALTH----YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCS 481
+R + YM P V+ +E PL +GKVDR+ + NN DA
Sbjct: 496 SIRRYMQEQAPDYMRPAAVVIMERFPLSASGKVDRKAFPVIAHGAANNGDA--------- 546
Query: 482 XXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVE 541
+LG G + F+ LGG+SL + + LR RG+ V+
Sbjct: 547 --TPPETALERLLAEVWSELLGVQDIGR---NAHFFNLGGHSLLIVKMMLALRRRGFIVD 601
Query: 542 ISDFLGASTLGEVLSKMST-DPNGGADSKEATFT 574
L ++ +++ D G + EA T
Sbjct: 602 AHTLYQHPVLADLATQLRRFDAQQGTATLEANET 635
>UniRef50_Q0S1Z9 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 5496
Score = 206 bits (504), Expect = 1e-51
Identities = 163/552 (29%), Positives = 254/552 (46%), Gaps = 38/552 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + AT AGAAY+P++P P R IL A+P+ ++ + D + VP +
Sbjct: 4700 VVGVYATLTAGAAYLPIDPHHPAERTHFILAVAQPTCIL-TTTHDEQVDLPDPVPVLHLD 4758
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + SA DA+ APL + A V++TSGSTG PKGV +++SAI N W
Sbjct: 4759 TI--DLSPLSAAPVTDADRHAPLRPQNTAYVMFTSGSTGRPKGVTVAHSAIVNEAQWVVE 4816
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + + + + A+TF S +++ PL G +++ + RDP L + R V
Sbjct: 4817 AFDHRAGDRL-LQSNAVTFDASTPDLFAPLQVGGCVVLAGPDGQRDPDYLAELIRAQKVT 4875
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + ++L L +S L LK+ GE+LS + ++ + N YG
Sbjct: 4876 HVASVPTVLTSLMASRSSDALDGLKVVYLGGESLSGNTVARLAEF----SPATVWNQYGP 4931
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE V + ++ +PIG P NC Y+LD L P + GE++VAG L
Sbjct: 4932 TETTVSVICHRCTQHEE----SVVPIGTPQTNCHAYVLDHRLHPVPVAVVGELYVAGVQL 4987
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY A RF NP+ P +R+YRTGD G + Y GR D QVK+RGHR
Sbjct: 4988 ARGYHNRPALTAERFVANPYG--PPGERMYRTGDLVRWHPDGTLEYLGRRDLQVKLRGHR 5045
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L P + V + ++G+V + GA I L
Sbjct: 5046 IELGEIEATLTTHPDITHAAVTVHHDHHTGDRLVGYVAPRNGAPLDPTTIHTFAADRLPD 5105
Query: 435 YMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P I + +++PL NGK+DRQ L T AV+
Sbjct: 5106 YMVPTPITILDALPLTTNGKIDRQALPTPVLPTPQYRAPVTAVE--------------GV 5151
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
VLG R + L F+ LGGNSL + +++LR+ G +++ ST+
Sbjct: 5152 VAWVFADVLG---RDRIGLDDDFFTLGGNSLLATQAVSRLREALGVEIQVMWLFTDSTVE 5208
Query: 553 EVLSKMSTDPNG 564
+ S++ +G
Sbjct: 5209 AIASRVEAASDG 5220
Score = 200 bits (489), Expect = 9e-50
Identities = 145/447 (32%), Positives = 219/447 (48%), Gaps = 24/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + AT AGAAY+P++P P R IL A+P+ ++ + D + VP +
Sbjct: 3641 VVGVYATLTAGAAYLPIDPHHPAERAHFILAVAQPTCIL-TTTHDEQVDLPDPVPVLHLD 3699
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + SA DA+ APL + A V++TSGSTG PKGV +++SAI N W
Sbjct: 3700 TI--DLSPLSAAPVTDADRHAPLRPQNTAYVMFTSGSTGRPKGVTVAHSAIVNEAQWV-- 3755
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F Y + + + A+TF S +++ PL G +++ + RDP L + R +
Sbjct: 3756 AFDYGLGDRL-LQSNAVTFDASTPDLFAPLQVGGCVVLAGPDGQRDPDYLAELIRTQAI- 3813
Query: 200 TLLRSILMYLALGPASRP---LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
T + S+ L ASR LR +++ GE+LS + + FG + N YG
Sbjct: 3814 THMSSVPTVLTALMASRSPDVLRGVRVVYLGGESLSGNTVARLAE-FGPATVW---NQYG 3869
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE V + ++ +PIG P NC Y+LD L P + GE++VAG
Sbjct: 3870 PTETTVSVICHRCTQHEE----SVVPIGTPQTNCHAYVLDHRLHPVPVAVVGELYVAGVQ 3925
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
LA GY A RF NP+ P +R+YRTGD G + Y GR D QVK+RGH
Sbjct: 3926 LARGYHNRPALTAERFVANPYG--PPGERMYRTGDLVRWHPDGTLEYLGRRDLQVKLRGH 3983
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L P + V + ++G+V + GAR + + L
Sbjct: 3984 RIELGEIEATLTTHPDITHAAVTVHHDHHTGDRLVGYVVPRDGARLDPARVRALVADRLP 4043
Query: 434 HYMMPQVIEV-ESIPLLVNGKVDRQGL 459
YM+P I V + +PL +GKVDR+ L
Sbjct: 4044 DYMVPSPITVLDRLPLTASGKVDRRAL 4070
Score = 159 bits (385), Expect = 3e-37
Identities = 132/458 (28%), Positives = 209/458 (45%), Gaps = 41/458 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+ AT K GAA++P++P++P+ RITH+L D+ +L + + + + +P+ +
Sbjct: 2081 ILAVWATTKTGAAFLPIDPNYPKDRITHMLSDSRAALGL--TTTEHATTLPGPLPWLVID 2138
Query: 80 ELAQEATSHSADE-PM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ ++ D P+ DA+ L PL + + A +LYTSGSTG PKGV +++ + N Q
Sbjct: 2139 TPDIQTRCNTIDPGPITDADRLRPLHTTNTAYLLYTSGSTGTPKGVVVTHQGLANLAAEQ 2198
Query: 138 ---FRTFPYS-------DSEEICVWKTALTF-VDSVCEIWGPLLHGRALLILSRETTRDP 186
F T P+S S + V++ L + I P + G L T
Sbjct: 2199 HERFTTTPHSRTLAVASPSFDASVFELLLAAGTGATMVIAPPTVFGGDELTHLLHTNHIT 2258
Query: 187 QKLVNIERLVLV-PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGN 245
++ L + PT L ++ L+ G A P L W +T FF +G
Sbjct: 2259 HAVITPAALATIDPTHLHTLHTVLSAGEACTP-DLLTRWTTHTDTSPTHTPRRFFNGYGP 2317
Query: 246 EDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDS 305
+ ++N G G +T IG P+ Y+LD+ L P
Sbjct: 2318 TETTVMSNCSGPLPPGGPIT-----------------IGGPIRGTHAYVLDDRLRPVPTG 2360
Query: 306 EPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAG 362
E+ +AG LA GY A RF NP+ P +R+YRTGD G + + G
Sbjct: 2361 VTAELHLAGIQLARGYHNRPALTAERFVANPYG--PPGERMYRTGDLVRWHPDGTLEFLG 2418
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R D Q+K+RGHR++L E+E L P + V + +++ +V PGA+
Sbjct: 2419 RRDLQIKLRGHRIELAEIEATLTTHPDITHAAVTVH-KGPVTEQLVAYVVPTPGAQIDPA 2477
Query: 423 HIEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
+ L YM+P I V + +PL NGK+DR+ L
Sbjct: 2478 RVRAFAADRLPDYMLPDPITVLDRLPLTPNGKIDRRAL 2515
Score = 157 bits (381), Expect = 1e-36
Identities = 131/458 (28%), Positives = 208/458 (45%), Gaps = 41/458 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+ AT K GAA++P++P++P+ RITH+L D+ +L + + + + +P+ +
Sbjct: 523 ILAVWATTKTGAAFLPIDPNYPKDRITHMLSDSRAALGL--TTTEHATTLPGPLPWLVID 580
Query: 80 ELAQEATSHSADE-PM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ ++ D P+ D + L PL + + A +LYTSGSTG PKGV +++ + N Q
Sbjct: 581 TPDIQTRCNTIDPGPITDTDRLRPLHTTNTAYLLYTSGSTGTPKGVVVTHQGLANLAAEQ 640
Query: 138 ---FRTFPYS-------DSEEICVWKTALTF-VDSVCEIWGPLLHGRALLILSRETTRDP 186
F T P+S S + V++ L + I P + G L T
Sbjct: 641 HERFTTTPHSRTLAVASPSFDASVFELLLAAGTGATMVIAPPTVFGGDELTHLLHTNHIT 700
Query: 187 QKLVNIERLVLV-PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGN 245
++ L + PT L ++ L+ G A P L W +T FF +G
Sbjct: 701 HAVITPAALATIDPTHLHTLHTVLSAGEACTP-DLLTRWTTHTDTSPTHTPRRFFNGYGP 759
Query: 246 EDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDS 305
+ ++N G G +T IG P+ Y+LD+ L P
Sbjct: 760 TETTVMSNCSGPLPPGGPIT-----------------IGGPIRGTHAYVLDDRLRPVPTG 802
Query: 306 EPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAG 362
E+ +AG LA GY A RF NP+ P +R+YRTGD G + + G
Sbjct: 803 VTAELHLAGIQLARGYHNRPALTAERFVANPYG--PPGERMYRTGDLVRWHPDGTLEFLG 860
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R D Q+K+RGHR++L E+E L P + V + +++ +V PGA+
Sbjct: 861 RRDLQIKLRGHRIELAEIEATLTTHPDITHAAVTVH-KGPVTEQLVAYVVPTPGAQIDPA 919
Query: 423 HIEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
+ L YM+P I V + +PL NGK+DR+ L
Sbjct: 920 RVRAFAADRLPDYMLPDPITVLDRLPLTPNGKIDRRAL 957
>UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=6; Pseudomonadaceae|Rep: Non-ribosomal
peptide synthase:Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 2883
Score = 206 bits (503), Expect = 2e-51
Identities = 147/450 (32%), Positives = 222/450 (49%), Gaps = 22/450 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++P +P+ R+ ++++D+ L++ + + + +
Sbjct: 2064 VIGLLAIIKAGGAYVPLDPDYPEDRLAYMMQDSGIGLLLTQTALLERLPVPPQLQSLCLD 2123
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +S P++ PL ++A V+YTSGSTG PKG S+ A+ NRL W +
Sbjct: 2124 QHGDWLEGYSTANPVNLSH--PL---NLAYVIYTSGSTGKPKGAGNSHRALVNRLHWMQK 2178
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ S+ + + KT +F SV E + PL+ G L + RDP++LV R V
Sbjct: 2179 AYALDGSDTV-LQKTPFSFDVSVWEFFWPLMTGARLAVALPGDHRDPERLVQTIREHQVT 2237
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL + S+L P L+ VCSGE L ELA++ K Y N YG
Sbjct: 2238 TLHFVPSMLQAFMTHPQVESCNTLRRVVCSGEALPAELAAQVLKRLPLAGLY---NLYGP 2294
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ D L ++PIGRP+DN ++LD+ L P E+++ G L
Sbjct: 2295 TEAAIDVTHWTCSTDDIL----SVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGVGL 2350
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHR 374
A GY A RF +P Q RLYRTGD V+ YAGR D QVKIRG R
Sbjct: 2351 ARGYHNRAALTAERFVPDPFDEQGG-GRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLR 2409
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA--QHIEGKLRSAL 432
++L E+E L + V + V+ G V T + ++ L++ +
Sbjct: 2410 IELGEIEARLHEHAAVREATVIDIDGPSGKQLAAYLVPTDATEAPDVLRERLQAHLKAHV 2469
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGLLK 461
YM+P + ++S+PL NGK+DR+ L K
Sbjct: 2470 PDYMVPGYFVFIDSMPLTANGKLDRRALPK 2499
Score = 182 bits (443), Expect = 3e-44
Identities = 137/452 (30%), Positives = 220/452 (48%), Gaps = 34/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGV-PFASF 78
+++LLA K GA Y+P++ + P R+ + +D+ L++Y + D GV P +F
Sbjct: 566 VVSLLAVLKLGAVYLPLDSAQPAERLQQLARDSGAVLLVY--ARDDDKAARLGVCPVLAF 623
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ A A +D L A ++YTSGSTG PKGV +S+ A+ N +
Sbjct: 624 DAALWAAVDSQA---LDVRVLP----GQAAYIIYTSGSTGQPKGVVISHGALANYVQGVL 676
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------I 192
SD + + T + ++G L GRAL +LS E DP +
Sbjct: 677 ERLALSDGASMAMVSTVAADLGHTL-LFGALASGRALHLLSHEQAFDPDGFARYMAEHQV 735
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+ L +VP+ L+ +L A PA + ++ + GE + L + + G ++
Sbjct: 736 DVLKIVPSHLQGLLQ--AANPAD--VLPGQVLILGGEASAWALVEQVRAL---KPGCRVI 788
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE + + + G L ++P+G+PL N +LD L+P + GE+++
Sbjct: 789 NHYGPTETTVGILTHEVAGP--LSACRSVPVGQPLANGKARVLDAYLNPVAERVAGELYL 846
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYAGRTDAQVKI 370
G LA GY+G A RF +P A QRLYR GD V G + Y GR D QVKI
Sbjct: 847 GGRGLAQGYLGRAAMTAERFVPDPDANG---QRLYRAGDRARWVDGVLEYLGRADDQVKI 903
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGL--DRGNPEILGFVTTKPGARTSAQHIEGKL 428
RG+RV+ EV + L + V VVL L D +++ + GA + + + G+L
Sbjct: 904 RGYRVEPGEVGQLLQTLENVADAVVLAQPLESDETRLQLVAYCVAAAGASLNVESLRGQL 963
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L Y++P Q++ +E +P+ NGK+D++ L
Sbjct: 964 AARLPEYLVPAQIMLLERLPVTANGKLDKRAL 995
>UniRef50_Q8GGQ3 Cluster: Nonribosomal peptide synthetase; n=2;
Streptomyces|Rep: Nonribosomal peptide synthetase -
Streptomyces atroolivaceus
Length = 1745
Score = 206 bits (502), Expect = 2e-51
Identities = 156/460 (33%), Positives = 228/460 (49%), Gaps = 32/460 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKE--SGVPFAS 77
++ALLA KAG AY+P++P P+ R+ L D PSL++ A E +G P +
Sbjct: 1188 VVALLAVVKAGGAYLPLDPDHPRARLALQLADVTPSLLVTSRDAAHGRAGELAAGSPGLT 1247
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E+ A + D P+D E P D++ VL+TSG+TG PKGV ++ + NR+ W
Sbjct: 1248 LVEIDDPALAELPDGPLD-EVARP---DNLLYVLHTSGTTGTPKGVMNRHAGVANRMAWM 1303
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERL 195
+P E + + KT + F S EIW PL HG +++ +DP LV ++
Sbjct: 1304 QEKYPLVAGERV-LHKTPVGFDVSGWEIWWPLGHGATIVLARPGGHQDPGYLVRSVVDHA 1362
Query: 196 V----LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
V VP++LR L A LRR+ VCSGE L ++A+ F + G +L
Sbjct: 1363 VTTCHFVPSMLRVFLDETTAATAGGTLRRV---VCSGEALPPDVAARFHRLL---PGVEL 1416
Query: 252 ANFYGSTEVMGDVTYYVLE-GSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
N YG TE DVT +E G+ P +PIGRP+ +Y+LD +P PGE+
Sbjct: 1417 HNLYGPTEAAIDVTAEQVEPGATD---RPRLPIGRPVPGVRLYVLDGRGNPAPVGVPGEL 1473
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQ 367
+ G +A GY G A F +P + RLYRTGD + G + Y GR D Q
Sbjct: 1474 HIGGPQVARGYFGRPSLTAAAFVPDPFGSG---GRLYRTGDRACWTEDGTLDYLGRIDHQ 1530
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEG 426
VKIRG RV+ E E LA+ P V VV+ G + ++ GA + H+
Sbjct: 1531 VKIRGQRVEPGESEAVLARHPAVGDAVVV-PRRQGGETYLAAYLVAVAGAEQPGPAHLRE 1589
Query: 427 KLRSALTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYEN 465
L +L M+P ++++P+ NGK+DR L + +N
Sbjct: 1590 HLSLSLPPAMIPSAYTWLDALPVGANGKLDRDALPEPDQN 1629
>UniRef50_Q0S6F3 Cluster: Non-ribosomal peptide synthetase; n=2;
cellular organisms|Rep: Non-ribosomal peptide synthetase
- Rhodococcus sp. (strain RHA1)
Length = 8939
Score = 206 bits (502), Expect = 2e-51
Identities = 143/456 (31%), Positives = 230/456 (50%), Gaps = 21/456 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA AG YVP++ S+P R+ + DA P + SA+ + +G+P + +
Sbjct: 1876 VVTLLAVLAAGGGYVPVDTSYPAERVAAMFDDARPVCAVV--SAEFASLAPAGIPVVAID 1933
Query: 80 ELAQE-ATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ A A + + P+ D++ L PL +D++A V++TSGSTG PKGV++S+ + L
Sbjct: 1934 DPATAGAMAELSGLPVTDSDRLRPLWADAVAYVIFTSGSTGRPKGVQVSHRCVVTLLANT 1993
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
F + DS ++ + F SV E+WG L+HG L+++ T R P + + R
Sbjct: 1994 RELFGF-DSSDVWTLFHSYAFDFSVWELWGALVHGGRLVLVDYFTARSPDTFLELLRRER 2052
Query: 198 VPTLLRSILMYLALGPASRPLRR----------LKLWVCSGETLSKELASEFFKYFGNED 247
V L ++ + L A R L+ + GE L ++ ++
Sbjct: 2053 VTVLNQTPTAFYQLTEADRAANAVNDAGGSPLSLRHVIFGGEALDVGQLERWYTRH-DDR 2111
Query: 248 GYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP 307
L N YG TE V++ L+ + + P IG L +Y+LD L P
Sbjct: 2112 APVLVNMYGITETTVHVSFLALDRALAASV-PGSVIGGGLPGLRVYVLDGRLHPVPPGVV 2170
Query: 308 GEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRT 364
GE++V+G + GY+G G + RF +P R+YR+GD G L Y GR+
Sbjct: 2171 GELYVSGDQVTRGYIGRQGLTSTRFVADPFDHHRAGARMYRSGDVVKWGAGGRLEYMGRS 2230
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHI 424
D QV++RG RV+L EVE ALA GV + VV+ G DR ++G+V + GA A +
Sbjct: 2231 DFQVQLRGFRVELGEVEAALAACAGVAQSVVVVRGDDRDGDRLVGYVVPETGADVDAAAV 2290
Query: 425 EGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ ++ YM+P V+ ++++PL VNGK+DR+ L
Sbjct: 2291 LDAVGESVPSYMVPAAVVVIDALPLTVNGKLDRKAL 2326
Score = 197 bits (481), Expect = 8e-49
Identities = 159/551 (28%), Positives = 255/551 (46%), Gaps = 38/551 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA K+GA YVP++ ++P R+ + DA P V+ + A+ + SGVP +
Sbjct: 5550 VVALLAVVKSGAGYVPVDVTYPAERLAFVFADARPVCVLTTE-AESDAVRASGVPLLLVD 5608
Query: 80 --ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E E S D + PL DS+A V+YTSGSTG PKGV++++ + L+
Sbjct: 5609 SAETVAELDRTSPLPVTDGDRTGPLRPDSVAYVIYTSGSTGQPKGVQVAHRNVVT-LFAN 5667
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
+ D+ ++ + F SV E+WG LLHG L+++ TTR P + + R
Sbjct: 5668 TQPLFRFDACDVWTMFHSAAFDFSVWELWGALLHGGRLVVVDYFTTRSPDMFLRLLRDEN 5727
Query: 198 VPTLLRSILMYLALGPASRPL----RRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V L ++ + L A R L++ V GE L + ++ + L N
Sbjct: 5728 VTVLNQTPTAFYQLAEADRVAGATELSLRVVVFGGEALDLGQLTRWYARH-VDTAPALVN 5786
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE V++ L+ ++ IGR L +Y+LD L P GE++V+
Sbjct: 5787 MYGITETTVHVSHLPLDAELAASASASV-IGRALPGLRVYVLDSRLHPVPPGVVGELYVS 5845
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G ++ GY+G + RF +PH R+YR+GD G G + Y GR D QV++
Sbjct: 5846 GPQVSRGYLGRFALTSTRFVADPHTPG---SRMYRSGDLGRWNADGQLEYLGRNDFQVQV 5902
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
+G R++L EVE AL GV + VVL ++G+V + G I +
Sbjct: 5903 KGFRIELGEVESALLACEGVAQSVVLA-----RRERLVGYVVPEAGRVLDPAGIVDAVAG 5957
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L +M+P V+ ++++PL VNGK+DR+ L E S
Sbjct: 5958 RLAAHMVPAAVVVLDALPLTVNGKLDRRAL------------PEPDFGRQVSLGRAPATE 6005
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
VLG + G + F+ +GG+S+ SI +T+ + G + D
Sbjct: 6006 TERILAGLFAEVLGLESVG---VDDSFFAVGGDSIMSIQLVTRAKASGVVITPRDVFERK 6062
Query: 550 TLGEVLSKMST 560
T+ L++++T
Sbjct: 6063 TVA-ALAEVAT 6072
Score = 166 bits (403), Expect = 2e-39
Identities = 151/520 (29%), Positives = 224/520 (43%), Gaps = 37/520 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++ + A + GA +VP++P++P RITH+L D+E +L + + + G
Sbjct: 7094 SVLCVWAVARTGAVFVPVDPNYPGERITHMLTDSECALGLTTSEHRARLPENIGWLVLDD 7153
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
A E + SA D + AP+T D+ A ++YTSGSTG PKGV +++ + N Q
Sbjct: 7154 PAFAAECAAASAAPVDDGDRTAPVTLDTAAYLVYTSGSTGRPKGVTVTHRGLDNFARDQL 7213
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
F + T +F SV E + A +++ T +L + R V
Sbjct: 7214 ARFGADPGSRTLHFSTP-SFDGSVFE-YLQAFGAAATMVIVPTTVFGGDELAQLIRDRHV 7271
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ +L PA L GE EL S + G +L N YG T
Sbjct: 7272 THAFVTTAALASLDPAG--LDHFTDVAVGGEACPPELVSRW------APGRRLYNAYGPT 7323
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T + SD L I IG P+ +LD L P PGE+++AGA LA
Sbjct: 7324 E-----TTVMSNISDPLTPGDRITIGGPIRGVTELVLDSRLQPVPAGVPGELYLAGAGLA 7378
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGHRV 375
GY G A RF +P QR+YRTGD + + Y GR+D QVK+RG R+
Sbjct: 7379 RGYHRRPGLTAERFVADPAEAG---QRMYRTGDIVRWTPERTIEYLGRSDFQVKVRGFRI 7435
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E++ L P V V + Y G+ + +V P + I +L L +
Sbjct: 7436 ELGEIDTTLTADPDVRFAVTVAYRGPAGDTLLASYVVPAPEHALDTETITRRLAGRLPSH 7495
Query: 436 MMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P I V + IPL GK DR+ L D+
Sbjct: 7496 MVPSSITVLDEIPLNAVGKFDRKAL------------PAPRFDVGAREYRAPADPVEETV 7543
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR 534
VLG A +S +GF++LGGNSL++ + +LR
Sbjct: 7544 AEVFAEVLGLA---RVSADAGFFDLGGNSLSATRAVARLR 7580
Score = 144 bits (348), Expect = 1e-32
Identities = 129/448 (28%), Positives = 207/448 (46%), Gaps = 29/448 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+ A KAGAA+VP++P++P RI H+L D+ +L + SA S VP+
Sbjct: 4492 SVLAVWAVAKAGAAFVPVDPNYPADRIEHMLADSGAALGV-TMSAHRHRLPGS-VPWLVL 4549
Query: 79 EELAQEATSHSAD--EPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
++ A + T +A D + + L D A +YTSGSTG PKGV +++ + N L
Sbjct: 4550 DDAAFDRTWAAASPVRVTDLDRRSVLDVDHAAYAIYTSGSTGRPKGVVVTHRGLANLLTE 4609
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
Q + S C+ + +F ++ E+ G L+I + + + R
Sbjct: 4610 QTEHYTVSPDSR-CLHICSPSFDVAILELVQSCAAGATLVIAPPDVYGGAELAALLRR-- 4666
Query: 197 LVPTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + + L R + L+ V +G+ + EL + + G + + N Y
Sbjct: 4667 --ERVTHACITPAVLATVERDGIEHLEALVVAGDAVGDELVAAW----GADRA--MFNGY 4718
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T+ S + + IG P+ A+ +LD L P PGE+++AG
Sbjct: 4719 GPTEATILTTF-----SRPMRPGEPVTIGGPVRGIALSVLDARLQPVPAGVPGELYIAGP 4773
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRG 372
LA GY A RF +P+ R+YRTGD + L Y GR+D QVKIRG
Sbjct: 4774 ALARGYHRRPALTAERFVADPYGGG----RMYRTGDVVRWSRDHTLEYLGRSDFQVKIRG 4829
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
RV+L E++ L P +D L G+ ++ +V G +A + L
Sbjct: 4830 QRVELGEIDSVLTTHPHLDFAATLGRPGPLGDTALVSYVLPHDGEEVAAPEVLAFAGRIL 4889
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P V+ ++ IPL GK+DR+ L
Sbjct: 4890 PKYMVPAAVVVLDEIPLTPVGKLDRKAL 4917
Score = 139 bits (337), Expect = 2e-31
Identities = 131/450 (29%), Positives = 206/450 (45%), Gaps = 28/450 (6%)
Query: 19 TIMALLATW---KAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPF 75
+I ++LA W K GAA++P++P+ P RI ++L D+ + + ++ + +P+
Sbjct: 2954 SIESVLAVWSVAKTGAAFLPVDPNHPAERIEYMLGDSGAVAGLTTAALRSAL--PASIPW 3011
Query: 76 A--SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
E E A DA+ + L D A V+YTSGSTG PKGV ++ + N
Sbjct: 3012 LVPGDPETEAELALLPAAAVTDADRTSALHVDHPAYVIYTSGSTGKPKGVVTTHRGLANF 3071
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
+ TF + + + + +F SV E+ + G A ++++ + +L +
Sbjct: 3072 AATEQNTFGTTAASRTLHFASP-SFDASVLELMLAIGPG-ATMVIASPSVYGGDELAELL 3129
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V + ++ PA L ++ V GET EL + + G + +
Sbjct: 3130 LRERVTHCFVTPAALASVDPAG--LESVQCVVTGGETCPPELVARW------APGRAMFD 3181
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + V S L + IG P +LD+ L P GE+++A
Sbjct: 3182 AYGPTE-----STVVSSISTPLAPGEPVTIGAPTLGFTAAVLDQRLHPVPAGVAGELYLA 3236
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY G A RF NP P R+YRTGD G + Y GRTD QVKI
Sbjct: 3237 GPALARGYHGRYPLTAERFVANPFG--PPGSRMYRTGDLVRWTADGQLDYLGRTDFQVKI 3294
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L EVE AL V V +R ++G+V +PGA + +
Sbjct: 3295 RGFRIELGEVESALLAHGDVAAAVADVRRDERSGDRLIGYVVPEPGADIDPGEVLQFAGT 3354
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P V+ + ++P+ V+GK+DR+ L
Sbjct: 3355 RLASYMVPAAVVVIAALPVTVHGKLDRKAL 3384
Score = 137 bits (331), Expect = 1e-30
Identities = 125/451 (27%), Positives = 208/451 (46%), Gaps = 31/451 (6%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ ++ A K GAA+VP++P++P RI ++L D+ L + +++A + +P+
Sbjct: 815 FRSVASVWAVAKTGAAFVPVDPNYPADRIDYMLADSGVVLGLTEEAARGRL--HDSIPWC 872
Query: 77 SFEE--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
++ + + S D++ + PL D+ A ++YTSGSTG PKGV +++ + N
Sbjct: 873 VLDDPDFQADCAARSGRPLTDSDRIQPLHLDNAAYLIYTSGSTGRPKGVTVTHRGLDNFA 932
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER 194
Q F + S + T +F SV E G ++++ + +L ++ R
Sbjct: 933 ADQQERFGATRSSRTLHFSTP-SFDASVFEYLQAFGVGATMVVVP-PSAYGGSELADLLR 990
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
V + + P S L V GE EL + + +L N
Sbjct: 991 SERVTHGFVTTAALGTIPPDS--LGDFLDVVVGGEACPPELVARW------APDRRLHNA 1042
Query: 255 YGSTE--VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE +M +++ + G I +G P+ +LD L P PGE+++
Sbjct: 1043 YGPTETTIMANISAPMTPGDP-------ITLGGPIRGAEEVVLDARLRPVPVGVPGELYI 1095
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVK 369
AGA +A GY G A RF +P+ R+YRTGD L Y R+D QVK
Sbjct: 1096 AGAGVARGYHRRPGLTAARFVADPYGRG----RMYRTGDVVRWRPDHTLEYLRRSDFQVK 1151
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++L E++ L P V V + G+ ++ +V PG + ++R
Sbjct: 1152 VRGFRIELGEIDAMLQTHPDVRLAVTIGRPGPSGDTVLVSYVVPAPGRPIETTELLRQVR 1211
Query: 430 SALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
+ L YM+P V+ V + IPL GK+DR L
Sbjct: 1212 NRLPAYMVPSVVVVLDEIPLNPVGKLDRAAL 1242
Score = 131 bits (316), Expect = 8e-29
Identities = 130/452 (28%), Positives = 204/452 (45%), Gaps = 35/452 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEP-SLVIYDDSADPSMFKESGVPFAS 77
+++++ A + GAA++P++P +P RI H+L D+ S V D + +
Sbjct: 8150 SVLSVWAVARTGAAFLPVDPGYPLDRIEHMLTDSGAVSGVTLRAHRDQLPGTVNWIVLDD 8209
Query: 78 FEELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
E+ +E + P+ DA+ APL A ++YTSGSTG+PKGV +++ + N
Sbjct: 8210 AED--EERIRLQSPAPVTDADRTAPLHEAHPAYLIYTSGSTGVPKGVAVTHRGLANLAAE 8267
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ--KLVNIER 194
+ + + + + +F SV E+ G L+I + L++ ER
Sbjct: 8268 ERDRLAVTPGARVLHFASP-SFDASVFELVMAFCAGATLVIAPPTIYGGTELAALLSDER 8326
Query: 195 L---VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ + PT L S + P L+ V +GE EL + + G ++
Sbjct: 8327 VSHGFVTPTALAS------MDPLG--FESLRTLVVAGEACPPELVARW------APGRRM 8372
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE T + SD L I +G P + +LD L P GE++
Sbjct: 8373 FNAYGPTE-----TTIMSNISDALVPGEPITLGAPTRGVSEVVLDSRLRPVPLGVVGELY 8427
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQV 368
V+G LA+GY G A+RF P P +R+YRTGD + G + Y GR+D QV
Sbjct: 8428 VSGRALASGYHRRPGLTASRFVAAPWG--PPGERMYRTGDVVRWRRDGTLEYVGRSDFQV 8485
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG R++ E++ L P V V + G P ++ +V GA + +
Sbjct: 8486 KIRGFRIEPGEIDAVLTDHPDVGFAVTIGRAGPAGEPLLVSYVRPIGGADVDTAELTRLV 8545
Query: 429 RSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
L +M+P I V E IPL GK+DR L
Sbjct: 8546 GERLPAHMVPAAIVVLEQIPLTPVGKLDRTAL 8577
>UniRef50_Q44103 Cluster: Peptide-synthetase; n=1; Amycolatopsis
mediterranei|Rep: Peptide-synthetase - Amycolatopsis
mediterranei (Nocardia mediterranei)
Length = 1324
Score = 205 bits (501), Expect = 3e-51
Identities = 169/544 (31%), Positives = 253/544 (46%), Gaps = 65/544 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA KAGAAYVP++P+ P R + D LV+ D D P+ F+
Sbjct: 410 VVAILAVLKAGAAYVPVDPAAPDDRAAFVFGDTGVRLVVTDQGTDG--------PWPVFD 461
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA++ +++SAD P P+ +A +++TSGSTG PKGV +++ +
Sbjct: 462 -LARDVSAYSADRPR-----VPVRPGDLAYLIFTSGSTGRPKGVAVAHEHAGRLMASGHA 515
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------N 191
F +++++ VW + F +V E+WGPL HG L+++ +R P+
Sbjct: 516 HFGFTETD---VWTLFHSYAFDWTVWELWGPLHHGGRLVLVPYLVSRSPEAFTALLADEG 572
Query: 192 IERLVLVPTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
+ L P+ LR + L P + P LR++ L GE L + ++F +
Sbjct: 573 VTMLCQTPSALRQLETELRTTPRALPALRQVML---GGEALDPAVVR---RWFAHASSAP 626
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE VT + + G + IG PL + + ++LDE L P PGE+
Sbjct: 627 LCNLYGITETTVHVTTHDVPGPAGFE---RSLIGTPLPHLSAHVLDEWLRPCPAGVPGEL 683
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQ 367
++ G LA GY G G A RF +P + P RLYRTGD L G + Y GR D+Q
Sbjct: 684 YIGGGALAHGYWGRAGLTAQRFLPDPFSPVPG-ARLYRTGDVARRLAGGGLEYVGRCDSQ 742
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VKIRG R++L E+E AL P V C V + DR + +VT P H
Sbjct: 743 VKIRGFRIELGEIEHALGAHPAVGACAVTVHD-DR----LAAYVTGGPDHAELRAH---- 793
Query: 428 LRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L +L +M+P + V + +P+ VNGK+DR L N
Sbjct: 794 LAKSLPEHMIPATVTVLDRLPVTVNGKLDRAALPAPAPRAAN-------------AYTAP 840
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
VLG G + F+ LGG+S+ +++ KLRDRG+ + D
Sbjct: 841 STPGERLLTELWSDVLGVPGAG---VHDNFFHLGGDSIRAVHLAGKLRDRGWTFTLPDLF 897
Query: 547 GAST 550
GA T
Sbjct: 898 GAPT 901
>UniRef50_Q0LP44 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2596
Score = 205 bits (501), Expect = 3e-51
Identities = 151/447 (33%), Positives = 233/447 (52%), Gaps = 33/447 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAGAAYVP +P++P R+ +L DA P +VI D ++ +P F+
Sbjct: 2050 VIALLAIVKAGAAYVPFDPAYPSERVLAMLADAAPRVVI----TDTPKLGQATIPVLLFD 2105
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ Q S S + P+ + PL + A ++YTSGSTG PKGV S+ AI NRL W +
Sbjct: 2106 QAWQPNHSLSFNPPI----IHPLNA---AYMIYTSGSTGKPKGVINSHQAIVNRLLWMQQ 2158
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + + ++ + KT +F SV E + PL+ G L++ D + L + V
Sbjct: 2159 RYQLT-AADVVLQKTPYSFDVSVWEFFWPLMTGAKLVVARPAGHLDRRYLAETIQAQKVT 2217
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
T+ + S+L P + L+ CSGE LS E ++ F + N D L N YG
Sbjct: 2218 TIHFVPSMLSLFLEEPQAANCTSLRQVFCSGEALSAETSARFCQTL-NAD---LHNLYGP 2273
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DV+ + + + + P++PIGRP+ N +Y+LD + P GE+ + G NL
Sbjct: 2274 TEAAVDVSAWHYQPNAE----PSVPIGRPIANTQLYILDARMQPVPVGVAGELLIGGLNL 2329
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY A RF +P+A+Q RLYRTGD GA+ Y GR D Q+K+RG R
Sbjct: 2330 ARGYAERPDLTAERFIPHPYASQAG-ARLYRTGDLARWRDDGAIEYLGRNDFQIKVRGIR 2388
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIEGKLRSALT 433
V+L E+E L+Q P + + VV + +++ + +P A + LR+ L
Sbjct: 2389 VELGEIEHQLSQHPAIAQIVVHHHA-----GQLVAYWVARPDQAVPEETALRSWLRARLP 2443
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
M+P +++ +PL NGK++R+ L
Sbjct: 2444 EAMIPAHWLQLAELPLSSNGKLNRKAL 2470
Score = 171 bits (417), Expect = 5e-41
Identities = 143/462 (30%), Positives = 224/462 (48%), Gaps = 40/462 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAGAAYVP++P++P+ R+ + DA ++
Sbjct: 523 VVGILAILKAGAAYVPLDPTYPRERLAFVQADAAIRHIVTQ---------------RHLR 567
Query: 80 ELAQEATSHSADEPMDAETLAP----LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
++ Q + D+PMDA P ++++ A V+YTSGSTG PKGV +S++ + RL
Sbjct: 568 DVVQAEQCYLLDQPMDAYPTTPPSVVCSTENPAYVIYTSGSTGNPKGVVVSHANVA-RLM 626
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
+ + ++ + F SV E+WG LL+G L+++ +R+P+ + R
Sbjct: 627 LATNAWYQFNQHDVWTLFHSYAFDFSVWELWGALLYGGHLVVVPYWVSRNPEAFHQLLRQ 686
Query: 196 VLVPTLLRSILMYLALGPA-SRPLRRLKLW--VCSGETLSKELASEFFKYFGNEDGYKLA 252
V L ++ + L A S +RL L + GE L + +F +G++ +L
Sbjct: 687 QHVTVLNQTPSAFYQLIQADSLAEQRLALRTVIFGGEALDLAQLAPWFARYGDQQP-QLV 745
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE VTY + +D ++ IG P+ + A+ +LD + GE++V
Sbjct: 746 NMYGITETTVHVTYRPIRLADLQAGLGSV-IGCPIPDLALAVLDAQGRQAGVGVAGELYV 804
Query: 313 AGANLAAGYVGGG--GANRFCDNPHATQ--PEFQRLYRTGDFGTL-VKGAVLYAGRTDAQ 367
GA +A GY+ A RF +T P R YR+GD G + Y GR D Q
Sbjct: 805 GGAGVAQGYLERPELNAQRFIQADASTPDLPSNSRWYRSGDLVRYWPNGELEYLGRIDLQ 864
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP-----GARTSAQ 422
VKIRG R++L E+E AL+Q V V+ G+ ++G++ K GA+T
Sbjct: 865 VKIRGFRIELGEIEAALSQHAAVQSAAVIVREDRPGHKRLVGYLIAKTQMRSVGAQTDPS 924
Query: 423 ----HIEGKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
I +LR L YM P +IE+ S PL NGK+DRQ L
Sbjct: 925 LDLAAINQQLRERLPEYMWPSALIELASFPLTSNGKLDRQAL 966
>UniRef50_Q3JQV3 Cluster: Nonribosomal peptide synthetase; n=24;
Burkholderia|Rep: Nonribosomal peptide synthetase -
Burkholderia pseudomallei (strain 1710b)
Length = 2979
Score = 204 bits (499), Expect = 5e-51
Identities = 159/553 (28%), Positives = 260/553 (47%), Gaps = 41/553 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA WK GAAY+P++P P R+ +L+ A ++ D + + +GVP +F+
Sbjct: 2198 VLTVLAIWKIGAAYIPIDPVLPGQRMREMLELAGAKALVVDAAVAAAEPAVAGVPRIAFD 2257
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L Q+ D ++ L+ + ++ VL+TSGSTG PKG + + + N + +
Sbjct: 2258 DLVQD------DPCLEDNPDVHLSGNDLSYVLFTSGSTGKPKGAMIEHIGMLNNIANKAL 2311
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+ + +++F SV +++ L G A + D L+ +
Sbjct: 2312 DLEMDEDSRV-AQNASMSFDVSVWQMFIALTKGGATFVYDERAVNDIAGLIRRMAADGVT 2370
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L +VPT L +++ YL P L+ + +GET+ L +F F KL N
Sbjct: 2371 ILEVVPTYLIAVVEYLEEHPECVRPASLRFLIVNGETVDATLIRRWFALF---PATKLIN 2427
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D+T++++ D++ + P +P+GR L N +Y++D+EL P GE+
Sbjct: 2428 AYGPTEASDDITHHIMSPGDEI-VNP-VPVGRALANFDLYIVDDELRPVPIGTRGEIVAT 2485
Query: 314 GANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKI 370
G + GY+G G A F +P + + RLYRTGD G + + G +++ GR D QVKI
Sbjct: 2486 GVGIGRGYIGMAGATAQAFVKSPFPDRYK-GRLYRTGDLGEMREDGVLMFHGRKDRQVKI 2544
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L EVE +L + V + VVL + + V GAR + I L++
Sbjct: 2545 RGMRIELDEVEASLRAIAAVRQAVVLAIRPENREAFLCACVVPLDGAR---EEIVDALKA 2601
Query: 431 ALTHYMMPQVIEVE-SIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P V E +P L +GKVDR L + N +E A+
Sbjct: 2602 KLPPYMVPSVFRFERELPQLPSGKVDRNRLREQCLNETPR-ASEHAL--------APRSP 2652
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
G VLG A G L F+ LGG+S +I K G +E++D
Sbjct: 2653 LERRLAEVFGEVLGHDAFGVL---DDFFALGGDSFKAIRIAAKY---GPPLEVTDIYDHP 2706
Query: 550 TLGEVLSKMSTDP 562
T+ + + + P
Sbjct: 2707 TIEALAAHLERAP 2719
Score = 167 bits (405), Expect = 1e-39
Identities = 162/586 (27%), Positives = 255/586 (43%), Gaps = 50/586 (8%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F + A+LAT KAG AYVP++P P R+ +L D+ +L++ + +P + +
Sbjct: 633 FDMVSAILATLKAGCAYVPIDPQLPADRVAFMLSDSAAALLL---TIEP--IRRERLASF 687
Query: 77 SFEELAQEATSHS-ADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
+ L +A + A P A + P + A VLYTSGSTG PKGV ++++ + N L
Sbjct: 688 DIDTLCLDAPAPPRAAPPRAAPAVDP---HAAAYVLYTSGSTGKPKGVAVTHANVTNLLD 744
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN---- 191
++P + + KT F SV E++G + +L IL+ + P +V
Sbjct: 745 VMEASYPVGAHDRYLL-KTNYAFDVSVPELFGWFVGDGSLAILAPQAEGSPDLIVEALLR 803
Query: 192 --IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
+ L P+LLR + A RL+ GE L+ LA++ + Y
Sbjct: 804 HGVTHLNFTPSLLRQFVTEAAADARFARGHRLRHVFVVGEELTSALANDAWHALRPATIY 863
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
N YG TE T Y +PIGR L N +Y+LDE + P PG+
Sbjct: 864 ---NMYGPTETTVFATGYAHTAPIPNG---RVPIGRALGNMRVYVLDERMRPMPIGMPGD 917
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDA 366
+++AG +A GY+ A RF +P R+Y TGD + +L + GRTD
Sbjct: 918 LYIAGDGVARGYLNRDELTAERFLPDPFTPG---GRIYMTGDLARWTRDGMLEFLGRTDQ 974
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE- 425
Q+KIRG+RV+L E+ AL P V + V+ G+ ++ +V GA + E
Sbjct: 975 QIKIRGYRVELDEIASALNAHPLVGEAAVILKREPDGDARLVAYVVPAEGAAAAPSRDER 1034
Query: 426 --------GKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAV 476
G L L YM+P ++P + GK+DR+ L + D A AV
Sbjct: 1035 ARLRDALVGALEQRLPDYMVPADYAFAHALPKGITGKLDRKALEALPVERPARDAALGAV 1094
Query: 477 DIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR 536
AVL A L + F+ +GG+S+ SI + R++
Sbjct: 1095 --------APRNDTQRALCAIWQAVLRVPA---LGVTDNFFAVGGDSILSIQAAARAREQ 1143
Query: 537 GYYVEISDFLGASTLGEVLSKMSTDPNGGADSKEATFTAVPMRDEH 582
G D T+ E+L+ +++ A+ +P+ H
Sbjct: 1144 GIVFSARDIFRHQTV-ELLAAHVRWQQAPDEARRASAGDMPLLPIH 1188
>UniRef50_Q9F9L4 Cluster: Micrococcin P1 peptide synthetase; n=1;
Staphylococcus equorum subsp. equorum|Rep: Micrococcin
P1 peptide synthetase - Staphylococcus equorum subsp.
equorum
Length = 915
Score = 204 bits (499), Expect = 5e-51
Identities = 145/526 (27%), Positives = 254/526 (48%), Gaps = 47/526 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
TI+ + KAG AYVP++P +P RI +IL+D++P +++ D D ++ ++
Sbjct: 220 TIIGIYGILKAGGAYVPIDPKYPIDRINYILEDSQPKVLLTDRELDEAI---------NY 270
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDS-IAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ T + E L ++ +S + V+YTSG+TG PKGV + NRL W
Sbjct: 271 GNKVIDLTETTRLEAFPTSNLKQISDESNLMYVIYTSGTTGKPKGVMAHSGGVMNRLNWV 330
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------N 191
+ D E+ ++KT TF SV EI+G + G +++L +P+K+ +
Sbjct: 331 INKYNV-DGEDTILFKTPYTFDVSVWEIFGWAMLGSQIVLLPSGEEGNPEKITELLEGYS 389
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ + VP++L + ++ ++ + +LK + SGE L E ++F + GN++ L
Sbjct: 390 VAMVHFVPSMLNMFVNFIKSTNNAQAISKLKYVLASGEALKPEQVNDFNHFIGNKNNTAL 449
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE DVT + E Y +IPIG+P+ N Y+L+E+ + PGE+
Sbjct: 450 LNLYGPTETTVDVTSFDCENH---KTYDSIPIGKPISNIQAYILNEDNNIMGIGVPGELC 506
Query: 312 VAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+AG + AGY+ +F DNP +LYRTGD G ++Y GR D QV
Sbjct: 507 IAGVGVTAGYLNRPELTQEKFIDNPFGK----GKLYRTGDLAKWNGDGNIIYIGRIDEQV 562
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG+R++L E+E L Q ++ ++ + I ++ + + ++ L
Sbjct: 563 KIRGYRIELGEIESILRQHTHINDVAIVARPMVDNELSICAYLVSDDSLDFGS--LKTSL 620
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
L YM+P + +++ +P+ NGK++++ L + + ++
Sbjct: 621 GQKLPDYMIPAYMTQLDELPVTSNGKLNKKALPE--------------IKVESKVYVAPT 666
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL 533
T AVL +S+ F+E+GG+SL +I I ++
Sbjct: 667 NDIESAVAETFEAVL---HVDQVSIHDNFFEMGGHSLKAISVINEI 709
>UniRef50_Q1RS70 Cluster: Hybrid NRPS/PKS; n=4; cellular
organisms|Rep: Hybrid NRPS/PKS - Bacillus
amyloliquefaciens
Length = 5433
Score = 204 bits (498), Expect = 7e-51
Identities = 146/455 (32%), Positives = 231/455 (50%), Gaps = 30/455 (6%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ +LA KAG AYVP++P+FP R+ H+L D+ S+V+ + M ++ +
Sbjct: 548 FEMVIGILAILKAGGAYVPLDPAFPNERMAHVLTDSGVSIVLTQEKTR-GMIEQLAIGGV 606
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDS-IAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
S E+ S S + L P + +A +LYTSGSTG PKGV + + AI N L
Sbjct: 607 STVEIENSGRSVSGAK------LTPRSKPHHLAYILYTSGSTGKPKGVMVEHRAIMNTLQ 660
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN---- 191
+ +P + E+ + KT F S+ E++G + L+IL ++PQ +
Sbjct: 661 FLEAEYPVAQ-EDAYLLKTNYVFDVSISELFGWFIGNGRLVILPPGAEKNPQLCMEYIQT 719
Query: 192 --IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
+ L P + L + A +K + +GE K+L + F +
Sbjct: 720 HQVTHLNFAPAVFNVFLETVKRHTAFTEDGPVKYVMVAGEAFPKDLVKKSVSIFKHA--- 776
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
++ N YG TE YY G ++ T PIG+P+ N +Y++DE+LSP D GE
Sbjct: 777 RIENIYGPTETSIYAAYYSC-GQKEITSRNT-PIGKPIHNTRLYIVDEKLSPVPDGVAGE 834
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
+ VAGA LA GY A F DNP + E ++LY+TGD L G + YAGR D+
Sbjct: 835 LCVAGAGLARGYYNQPELTAASFIDNPFS---EGEKLYKTGDLARWLPDGNIEYAGRIDS 891
Query: 367 QVKIRGHRVDLLEVERALAQVPGV-DKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
QVKIRG R++L +E L++ P + D+ VV+ G+ +++ + T + G + +
Sbjct: 892 QVKIRGFRIELGAIETKLSEHPDILDQAVVV--QEKNGHKKLIAYYTARSGHTADEKALR 949
Query: 426 GKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L S+L YM P I ++++PL +GKV+R+ L
Sbjct: 950 NHLLSSLPDYMAPAHFIRLDALPLTPSGKVNRKDL 984
>UniRef50_A1TTJ0 Cluster: Amino acid adenylation domain; n=1;
Acidovorax avenae subsp. citrulli AAC00-1|Rep: Amino acid
adenylation domain - Acidovorax avenae subsp. citrulli
(strain AAC00-1)
Length = 1130
Score = 204 bits (498), Expect = 7e-51
Identities = 150/450 (33%), Positives = 220/450 (48%), Gaps = 30/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ALLA KAG AYVP++P P RI ++L D P+LV+ D + + P
Sbjct: 590 VEALLAVLKAGGAYVPLDPELPADRIAYMLGDCAPALVLTDAAHRACLPAAMAQPVV--- 646
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + D A L ++ +A V+YTSGSTG PKG + A+ NR+ W R
Sbjct: 647 -LLPLEDAPPGDGAEAACLPVALHAEHLAYVIYTSGSTGRPKGAANRHGALSNRIAWMQR 705
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVN---IE 193
+ + + + KT F SV E + PL G L + R+P Q L+ +
Sbjct: 706 AYGLGPGDTV-LQKTPFGFDVSVWEFFWPLAVGARLAVAPPGAHREPAHLQALIQRHAVT 764
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L+++L L A +RR+ VCSGE L E + + G L N
Sbjct: 765 TLHFVPSMLQALLAQLD-AHACASVRRI---VCSGEALPAEARRQVLERL---PGVALHN 817
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ ++ +PIGRP+ ++LD + P PGE+++
Sbjct: 818 LYGPTEAAIDVTHWTCHAQER----GPVPIGRPIAGLRTHVLDAAMQPVPPGAPGELFLG 873
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKI 370
GA LA GY G A RF +P +P RLYRTGD G++ Y GR D QVKI
Sbjct: 874 GAGLARGYAARPGLTAERFVADPF--EPG-ARLYRTGDLVRWRGDGSLEYLGRLDHQVKI 930
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L PGV + V + G ++ + + GA + + +L +
Sbjct: 931 RGQRIELGEIEARLLARPGVREAVAVAASTPAGT-ALVAYCSPHAGATLDGEALRARLAA 989
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L M+P Q+ + ++PL NGKVDR+ L
Sbjct: 990 ELPEAMVPSQIAVLPALPLNANGKVDRKAL 1019
>UniRef50_UPI00005F935B Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=2; cellular
organisms|Rep: COG1020: Non-ribosomal peptide synthetase
modules and related proteins - Yersinia frederiksenii
ATCC 33641
Length = 2401
Score = 204 bits (497), Expect = 9e-51
Identities = 149/459 (32%), Positives = 237/459 (51%), Gaps = 39/459 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+AL+A AGAAY+P++ +P R+ +++ DA+P L+I ++ ++ P ++
Sbjct: 1622 LALMAILAAGAAYLPLDTGYPDDRLAYMISDAKPRLIITINALAERFAGQA--PLLLLDQ 1679
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
L S+D+ + +T D A ++YTSGSTG PKGV +S+ AI NRL W
Sbjct: 1680 LP------SSDQLPQLPAVV-ITPDHPAYLIYTSGSTGRPKGVVVSHGAIVNRLLWMQNE 1732
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VNIER 194
+P S+++ + KT +F SV E + P++ G L++ + RDP L +
Sbjct: 1733 YPLG-SDDVVLQKTPCSFDVSVWEFFWPMITGARLVMAPPQAHRDPDALRAIIEDYGVTT 1791
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
VP++L + + A+ +P L+ CSGE LS+EL+ + F L N
Sbjct: 1792 AHFVPSMLAAFVS--AMHGQRQPCPSLRRVFCSGEALSRELSQLYQHIF----SAPLHNL 1845
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLY-PTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVTY G + ++PIG+P+ N + +LD L G++++
Sbjct: 1846 YGPTEAAVDVTYQPAYGDALARVTGSSVPIGKPVWNTQLRILDGMLRQVPVGIAGDLYLC 1905
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA LA GY A+RF +P+ QR+YRTGD L G V Y GR+D Q+KI
Sbjct: 1906 GAQLAHGYYARPDLTASRFVADPY---DRGQRMYRTGDIARWLPDGTVEYLGRSDDQLKI 1962
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGL--DRG------NPEILGFVTTKPGA-RTSA 421
RG R++L E+E AL ++P V + VV L + G +++G++ GA T
Sbjct: 1963 RGQRIELGEIESALLELPQVQQAVVHARTLVGEEGALAGADTRQLVGYIVPVAGAEETDM 2022
Query: 422 QHIEGKLRSALTHYMMPQVI-EVESIPLLVNGKVDRQGL 459
+ +L L +M+P +I +++ PL NGK+DR+ L
Sbjct: 2023 ATLRNQLSERLPPHMVPVIIVSLKAFPLSANGKLDRKAL 2061
Score = 159 bits (385), Expect = 3e-37
Identities = 131/465 (28%), Positives = 214/465 (46%), Gaps = 38/465 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVI-YDDSADP--SMFKESGVPF 75
+++A+L +GAAY+P++ +P R+T + +DA P L++ Y + D + SG+P
Sbjct: 543 SLVAILGVLASGAAYMPLDLDYPMDRLTLMCEDASPRLLLAYQSTEDVLLPLTATSGMPL 602
Query: 76 ASFEE--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAI--- 130
++ +E + S D E P+ D +A ++YTSGSTG PKGV ++ +
Sbjct: 603 VCLDDDIFRRECAAFSTQLISDPERRQPMQGDHLAYMIYTSGSTGRPKGVMSTHGGLVNL 662
Query: 131 ----CNRLWWQ-FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRD 185
C L+ F ++ + TA DS E ++ G ++I E RD
Sbjct: 663 LLAHCTHLYGPAMAEFKQHNARRMRAGHTASFSFDSSWEPLFWMMMGCEMVIFDEEMRRD 722
Query: 186 PQKLVNIERLVLVPTLLRSILMYLAL---GPASRPLRRLKLWVCSGETLSKELASEFFKY 242
LV V + T+ + + + G R + GE + L +
Sbjct: 723 VYALVQTMDQVPIDTMDITPSFFTQMIDSGLLEEGRHRPAFIMIGGEAATPRL----WDL 778
Query: 243 FGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPT 302
+ NFYG +E D L + ++ P I GRP+ N +YLLD +L+
Sbjct: 779 LKQHPELNVVNFYGPSEYTIDT----LGANTKVSEQPVI--GRPVANTEVYLLDSQLTKV 832
Query: 303 RDSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVL 359
GE+++AG LA GY+ A RF NP + +YR+GD +G +
Sbjct: 833 PVGAVGELYIAGPGLARGYLNRPDLTAARFVANPFR---HGEVMYRSGDLMRWTAQGQLD 889
Query: 360 YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART 419
+ GR D Q+K+RG RV+L E+E AL +P V VV+ + ++G+
Sbjct: 890 FVGRIDHQIKVRGFRVELGEIENALVALPEVSSAVVIAEAIG-ATHRLIGYCAVPDVQLR 948
Query: 420 SAQHIEGKLRS----ALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
++ + +L S L YM+P ++ V + +PL VNGK+DRQ L
Sbjct: 949 ASDDLNTRLMSQLAVTLPDYMVPAILMVLDEMPLTVNGKIDRQAL 993
>UniRef50_Q847C8 Cluster: NdaB; n=32; Cyanobacteria|Rep: NdaB -
Nodularia spumigena
Length = 1299
Score = 204 bits (497), Expect = 9e-51
Identities = 150/455 (32%), Positives = 221/455 (48%), Gaps = 32/455 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAG AY+P++PS+P R+ ++L DA S+++ S S+ P E
Sbjct: 542 VIGILGILKAGGAYLPLDPSYPADRLAYMLSDAALSILLTQQSLIASL------PTNQAE 595
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L ++ ++ +TS ++A V+YTSGSTG PKGV + ICN L
Sbjct: 596 VLCLDSDWQLIAHYSQQNPVSQVTSANLAYVIYTSGSTGKPKGVMNLHQGICNNLLRTID 655
Query: 140 TFPYSDSEEICVWK-------TALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN- 191
+P +E+ V K T +F SV EI+ PL+ G L++ E +DP L+N
Sbjct: 656 AYPLI-AEDAWVGKSQRIVQITPFSFDVSVWEIFWPLIAGATLVVAKPEGHKDPNYLINL 714
Query: 192 -IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
+++ V + SIL P L+ C GE LS EL +FF N +
Sbjct: 715 IVQQQVTQINFVPSILRVFLQQPNLETCSCLQRVFCGGEALSYELTQQFF----NRLNCE 770
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L NFYG TE D T + Y +PIGRP+ N IY+LD +L P PGE+
Sbjct: 771 LYNFYGPTETAVDATTWQCTPQSN---YQIVPIGRPIANTQIYILDSQLQPVPIGIPGEL 827
Query: 311 WVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQ 367
+ G LA GY+ A +F NP +LY+TGD L G + Y GR D Q
Sbjct: 828 HIGGIPLARGYLNQPELTAQKFIPNPFGN----GKLYKTGDLARYLPDGNIEYLGRIDNQ 883
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VK+RG R++L E+E L P V + VV+ N +++ +V K + T + +
Sbjct: 884 VKLRGLRIELGEIESVLDTHPQVGQTVVILREDIAENKQLVAYVLRKDQSLTPGE-LRRF 942
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLK 461
L+ L YM+P + + PL NGK+D + L K
Sbjct: 943 LQDKLPGYMIPSAFVILLDFPLNPNGKIDYKKLPK 977
>UniRef50_A5IDB4 Cluster: Peptide synthetase; n=4; Legionella
pneumophila|Rep: Peptide synthetase - Legionella
pneumophila (strain Corby)
Length = 507
Score = 204 bits (497), Expect = 9e-51
Identities = 140/455 (30%), Positives = 233/455 (51%), Gaps = 30/455 (6%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++A+ A KAG AY+P++P P R IL+D++ +I D + + SG+
Sbjct: 69 FEMLVAIFAVLKAGGAYLPIDPMAPVLRNQAILEDSQIKFLIVSDHS--LLTATSGLQVL 126
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
S + H+ + P + LA V+YTSG+TG PKGV +S+ A+ NR+ W
Sbjct: 127 SIHANVSDEDCHNLNLPRKKQDLA--------YVMYTSGTTGKPKGVLISHQALLNRILW 178
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------ 190
TFP S ++ KT + F SV E + G +++L D + +
Sbjct: 179 MQNTFPL-QSHDVVFHKTHICFDISVWETCWWSIVGAGVVLLPPRKEHDIKLFIQMIEQY 237
Query: 191 NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
I + VP++LR L Y+ + L LK SGE L + + F + F ++
Sbjct: 238 QINVIHFVPSVLRIFLSYIEQDFSINRLSSLKYVFSSGEALDAKSVNLFNQLFQDQKTI- 296
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE DV+ ++ E + D T+PIG+P+ N ++LDE+L+ T EPGE+
Sbjct: 297 LVNLYGPTEATIDVSCFICEKHKRFD---TVPIGKPIQNTQFFVLDEQLNST-GFEPGEL 352
Query: 311 WVAGANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQ 367
+++G LA GY+ + F DNP+ +++YRTGD +G +L+ GR D Q
Sbjct: 353 YISGVGLAQGYLNNPVLTQASFIDNPYLPG---EKMYRTGDIVRWNQEGELLFLGRKDDQ 409
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGF-VTTKPGARTSAQHIEG 426
VK+RG R++L E++ L P + VV+C +D + ++ F + + + ++
Sbjct: 410 VKLRGIRIELGEIQHHLLAHPNIHDAVVVCEKVDCLDHRMVVFLIANNKQTKIGSAELKS 469
Query: 427 KLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLL 460
L++ L YM+P+ + + + P+ NGK+D++ LL
Sbjct: 470 FLKNRLPDYMIPEHYLWLSAFPIKENGKIDKEKLL 504
>UniRef50_A1B557 Cluster: Amino acid adenylation domain; n=2;
Proteobacteria|Rep: Amino acid adenylation domain -
Paracoccus denitrificans (strain Pd 1222)
Length = 1304
Score = 203 bits (496), Expect = 1e-50
Identities = 152/445 (34%), Positives = 224/445 (50%), Gaps = 36/445 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ALLA +AGAAY+P++P+ P RI IL A+P V+ +AD + G+ A +
Sbjct: 539 VALLAILRAGAAYLPLDPAHPPERIARILAQAQPVAVL--STADLA-----GLFPAGTDP 591
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
L D P + A +A V++TSGSTG PKGV + + AI NRL W
Sbjct: 592 LLP------GDWPAEGRPKARPQPGDLAYVIFTSGSTGEPKGVAVEHRAIVNRLMWMQAH 645
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVLV 198
+ + + I + KT TF SV E + P++ G L++ RDP + +R V
Sbjct: 646 YGIAPDDRI-LQKTPATFDVSVWEFFLPMIAGAELVMAPPGAHRDPAAIAKAIRDRAVTT 704
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ S+L PAS+ L +++ CSGE L+ + F E L N YG T
Sbjct: 705 CHFVPSMLSAFLASPASQGLAMRRVF-CSGEELTADQRDRFHARIKAE----LHNLYGPT 759
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E DV+Y+ D+ + IPIG P+ N A+ +LD+ + P G +++ G LA
Sbjct: 760 EAAVDVSYWPAGPEDRTN---PIPIGWPVWNTALEVLDDRMRPVPPGLAGHLYLGGVQLA 816
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
GY+G A RF D P RLY TGD L GAV+Y GR+D QVKIRG RV
Sbjct: 817 RGYLGRPDLTAERFVDGPSG------RLYATGDLARLRPDGAVVYLGRSDHQVKIRGLRV 870
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E A+ +CVV+ G ++G++ PG + +L + L Y
Sbjct: 871 ELGEIEAAIMATGMARECVVIAREDHAGEKRLVGYLV--PGEDWRPGLLAERLAAGLPAY 928
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGL 459
M+P + +E++P+ NGK+DR+ L
Sbjct: 929 MVPSAEVALEALPVTSNGKLDRKAL 953
>UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C
[Includes: ATP-dependent valine adenylase (ValA) (Valine
activase); ATP-dependent D-valine adenylase (D-ValA)
(D-valine activase); Valine racemase [ATP-hydrolyzing]
(EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA)
(Tryptophan activase); ATP-dependent D-leucine adenylase
(D-LeuA) (D-leucine activase); Leucine racemase
[ATP-hydrolyzing] (EC 5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)]; n=11; cellular organisms|Rep: Linear
gramicidin synthetase subunit C [Includes: ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
D-valine adenylase (D-ValA) (D-valine activase); Valine
racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent
tryptophan adenylase (TrpA) (Tryptophan activase);
ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine
activase); Leucine racemase [ATP-hydrolyzing] (EC
5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)] - Brevibacillus parabrevis
Length = 7756
Score = 203 bits (495), Expect = 2e-50
Identities = 146/445 (32%), Positives = 225/445 (50%), Gaps = 30/445 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A L KAGAAYVP++P+ PQ RI ++++D++ S+++ S + P +S +
Sbjct: 5706 IVAFLGVMKAGAAYVPLDPAHPQERIAYMIEDSQASVLLTQASLTDRL------PASSRQ 5759
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ ++ A+EP+ +AET + ++A V+YTSGSTG+PKGV + + ++ N +
Sbjct: 5760 VICLDS-DELANEPVTNAET--SVGEHNLAYVIYTSGSTGLPKGVMIEHRSVINLAYDLI 5816
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
R F + + + + +F SV EI LL G L+I RE+ +L+ + + +
Sbjct: 5817 RHFQIDATSRVLQF-ISFSFDVSVSEIVMSLLAGATLVIEDRESLLPGPELIRVLQEQRI 5875
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
T + AL A P L+ + GE S+EL + + G + N YG T
Sbjct: 5876 TTFAMVSSVLAALPEADLP--DLRTIIVGGEAPSRELVARY------ATGRQFINCYGPT 5927
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T + + PIGRP+ N +Y+LD L P PGE+++ G +A
Sbjct: 5928 ETTVTATLKHCQDDGK-----NPPIGRPIANTTVYVLDAHLQPVPIGVPGELYIGGKGVA 5982
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY A RF +P E RLYRTGD L G + + GR D QVKIRG+R+
Sbjct: 5983 RGYWNRPELTAERFIADPFGQADE--RLYRTGDLVRYLENGELEFLGRIDDQVKIRGYRI 6040
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E AL Q P V VV+ G+ + ++ G + + L+S L Y
Sbjct: 6041 ELGEIENALRQHPAVQNVVVIARQEGAGDKRLAAYLVAATGQQPDEAELVRYLKSTLPEY 6100
Query: 436 MMPQ-VIEVESIPLLVNGKVDRQGL 459
M+P + +E IPL VNGKVDR+ L
Sbjct: 6101 MVPAGYVWLEKIPLTVNGKVDRRAL 6125
Score = 200 bits (489), Expect = 9e-50
Identities = 144/445 (32%), Positives = 227/445 (51%), Gaps = 35/445 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFK-ESGVPFASF 78
I+ + KAGAAYVP++P+ PQ RI ++++D++ S+++ S + K ++ V
Sbjct: 3127 IIGIFGVMKAGAAYVPIDPALPQERIAYMVEDSQASILLTQQSLAELLPKTQARVICLDG 3186
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ LA E ++ A E +T ++A V+YTSGSTG+PKGV + + ++ N
Sbjct: 3187 DSLANEPVANPASE---------VTEQNLAYVMYTSGSTGLPKGVMVEHHSVVNLAHALI 3237
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
F S + + T+ +F SV EI LL G AL+I RE +L+++ + +
Sbjct: 3238 EAFRIQPSSRVLQF-TSFSFDVSVSEIVMALLAGAALVIEDREVLLPGPELISVLQQKRI 3296
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
T+ + AL A P L+ + GE S+EL + + D + N YG T
Sbjct: 3297 TTVSMVSSVLAALPAADLP--DLQTLIVGGEAPSRELVARY------ADRRQFFNCYGPT 3348
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T + + + PIGRPL N +Y+LD P PGE+++ G LA
Sbjct: 3349 EATVCSTMMLCNAGMK-----SAPIGRPLANATLYVLDANQKPVPVGVPGELYIGGKGLA 3403
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY A RF +P + E RLYRTGD L G + + GR D QVKIRG+R+
Sbjct: 3404 RGYWNRPELTAERFIAHPFGAKGE--RLYRTGDLVRYLPDGNLEFLGRIDTQVKIRGYRI 3461
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E AL+Q P + + VV+ + + ++ A+ +A+ + L+ L Y
Sbjct: 3462 ELGEIESALSQHPAIQEAVVIAW-----EQRLAAYMVAAGEAQPAAEELARYLKETLPDY 3516
Query: 436 MMPQ-VIEVESIPLLVNGKVDRQGL 459
M+P + +++IPL VNGKVDR+ L
Sbjct: 3517 MIPAGFVFMDAIPLTVNGKVDRRAL 3541
Score = 195 bits (476), Expect = 3e-48
Identities = 153/521 (29%), Positives = 249/521 (47%), Gaps = 33/521 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++P++P+ R+ +L DA+ S+++ + K+
Sbjct: 532 LIGLLAILKAGGAYVPIDPAYPEERLAFMLADAKISILL----TQKHLGKQWKGRKRRTV 587
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L ++A + + P+ + T DS+A V+YTSGSTG PKGV + + RL + R
Sbjct: 588 YLDRDAKKWAEESPLAPDV--DTTKDSLAYVIYTSGSTGTPKGVLAVHRGVV-RLGQKTR 644
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T ++ + + ++F + EIWG LL+G L+++ + + I + +
Sbjct: 645 TTSPISEADVFLQASTVSFDAATFEIWGALLNGAKLVLMPPDLPSLDELGEAIVQHKVTT 704
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + + + LR ++ + G+ +S + G + N YG TE
Sbjct: 705 LWLTAGLFSIMVDHNADYLRGVRQLLVGGDVVSVPHVRKVLAL----GGVTVINGYGPTE 760
Query: 260 -VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
Y V E S+ + +P IGRP+ N +Y+LD+ P GE+++ G LA
Sbjct: 761 NTTFTCCYPVTELSEDITSFP---IGRPISNTTVYVLDKHKQPVPYGAAGELYIGGDGLA 817
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +NP Q + RLYRTGD L G + + GR D QVKIRG R+
Sbjct: 818 LGYLNNAELTAERFVENPFDPQ-KGSRLYRTGDLVRYLPNGTIEFIGRIDNQVKIRGFRI 876
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L EVE ALA P V + VV+ DRG + +VT ++ L++ L Y
Sbjct: 877 ELGEVEAALALHPEVSETVVMARENDRGEKHLTAYVTVAKDDAPEVADLQAWLKTKLPEY 936
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P + ++++PL NGK+DR+ L + N + + +
Sbjct: 937 MVPSAYVFLDAMPLTANGKIDRRRLPE--PEWGNRSETKAYTE--------PRNQAEELI 986
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
VLG G + F+ELGG+SL + I++LR+
Sbjct: 987 ASIWSQVLGVEKVG---IHDNFFELGGHSLLATRVISRLRE 1024
Score = 195 bits (476), Expect = 3e-48
Identities = 155/541 (28%), Positives = 253/541 (46%), Gaps = 34/541 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++P++P+ R+ +L DA S+++ + K+
Sbjct: 1598 LVGLLAILKAGGAYVPLDPAYPEERLAFMLADANVSILL----TQKHLGKQWKGRKRRTV 1653
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L ++A +A+ P+ A T DS+A V+YTSGSTG PKGV +++ I + +
Sbjct: 1654 YLDRDAKKWTAESPLAPAVDA--TKDSLAYVIYTSGSTGTPKGVLVAHRGIVRLV--KNT 1709
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ E++ + + ++F + EIWG LL+G L+++ + + I + +
Sbjct: 1710 NYVTITEEDVFLQASTVSFDAATFEIWGALLNGAKLVLMPPDLPSLDELGEAIVQHKVTT 1769
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + + + LR ++ + G+ +S + DG + N YG TE
Sbjct: 1770 LWLTAGLFSIMVDHNADYLRGVRQLLVGGDVVSVPHVRKVLAL----DGVTVINGYGPTE 1825
Query: 260 -VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
Y V E ++++ +P IGRP+ N +Y+LD+ P GE+++ G LA
Sbjct: 1826 NTTFTCCYPVTELAEEITSFP---IGRPISNTTVYVLDKNRQPVPLGVAGELYIGGDGLA 1882
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
+GY+ A RF DNP Q + RLYRTGD L GA+ + GR D QVKIRG R+
Sbjct: 1883 SGYLNNPELTAERFVDNPFDPQ-KASRLYRTGDLVRYLPDGAIEFIGRIDNQVKIRGFRI 1941
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E AL + P V + ++ G+ + ++ G + L+ L Y
Sbjct: 1942 ELGEIETALLRHPAVQEAFLMVREDAPGDKRLAAYLVFAGGQTVEPVEMRSYLKDKLPEY 2001
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P ++++S PL NGKVDR+ L E A S
Sbjct: 2002 MIPSAFVQMDSFPLTPNGKVDRRAL----------PTPEYARSEAASGYVAPATELEVKL 2051
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEV 554
VLG A G + F+ELGG+S+ SI + + G + T+ E+
Sbjct: 2052 ADIWKTVLGVADVG---IHDNFFELGGDSILSIQIVARANQLGIRLTPKQLFENQTIAEL 2108
Query: 555 L 555
L
Sbjct: 2109 L 2109
Score = 186 bits (453), Expect = 2e-45
Identities = 163/549 (29%), Positives = 247/549 (44%), Gaps = 47/549 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A L KAG AYVPM+P++PQ R+ +++DAE +V+ + + P A
Sbjct: 4176 LVAQLGILKAGGAYVPMDPAYPQERLAFMMQDAEMPVVLTQEHLLAQL------PEARAT 4229
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + E D + D++A V+YTSGSTG PKGV + ++A+ N + W R
Sbjct: 4230 FLCLDRDWSLIAEESDVAPVIATNRDNLAYVIYTSGSTGTPKGVEIEHAALLNLVSWHQR 4289
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL-----VNIER 194
+ +E+ F SV EIW L G L + S E P++L +
Sbjct: 4290 AYEVG-AEDRATQIAGTAFDASVWEIWPYLTKGATLYLPSEEIRLVPEQLRDWLVASGIT 4348
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ +PT L L+ L P+ LR + + G+ L + + LAN
Sbjct: 4349 ISFLPTPLAERLLTLEW-PSDAKLRYM---LTGGDKLHDYPPATL--------PFVLANQ 4396
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE T ++ + P+I GRP+DN +Y+LDE+L P GE+++AG
Sbjct: 4397 YGPTENAVVATAGIVPAAAGQVSAPSI--GRPIDNVQVYVLDEKLQPVPIGVAGELYIAG 4454
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIR 371
+LA GY+ RF NP+ Q R+Y+TGD L G + + GR D QV IR
Sbjct: 4455 DSLARGYLHRPDLTRERFIANPYG-QKAGARMYKTGDLVRYLPDGNIEFIGRADDQVSIR 4513
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR---TSAQHIEGKL 428
G RV+L E+E AL P V + +VL G ++ ++ + G A L
Sbjct: 4514 GFRVELGEIETALYSHPAVKETIVLVREDMPGMKRLVAYIVQREGQEGQAVQAGDFRSYL 4573
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
+ L YM+P + + +PL NGKVDR+ L + D VA +
Sbjct: 4574 KELLPEYMVPAAFVFMADLPLTPNGKVDRRALPAPDLFNSEADGTYVAPATELEIKLAHI 4633
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
VLG A G + F+ELGG+S+ SI +++ G + L
Sbjct: 4634 WKN----------VLGLADVG---IHDNFFELGGDSILSIQIVSRANQAGIRLTPKQLLA 4680
Query: 548 ASTLGEVLS 556
T+ E+ S
Sbjct: 4681 NQTIAELAS 4689
Score = 176 bits (429), Expect = 2e-42
Identities = 142/450 (31%), Positives = 217/450 (48%), Gaps = 33/450 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ L KAG A+VPM+P++PQ R+ ++ D V+ + + + A+F
Sbjct: 6760 IVGQLGILKAGGAFVPMDPAYPQERLAFMMADTGMPFVLTQER----LLETLPAGDAAFI 6815
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + A+E A LA +T+D +A V+YTSGSTG PKGV + + A+ N ++W
Sbjct: 6816 CLDAD-WEVIAEESTQAPELA-VTTDQLAYVIYTSGSTGTPKGVEIEHRALLNLIYWHQH 6873
Query: 140 TFPYS-DSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN---IERL 195
+ + D + TA F +V EIW + G L + E P+KL + E +
Sbjct: 6874 AYTITPDDRASQIAGTA--FDAAVWEIWPYMTAGATLYLPQEEIRLIPEKLRDWLVAEGI 6931
Query: 196 VL--VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ +PT L ++ + P+ LR +V +G + Y + L N
Sbjct: 6932 TISFLPTPLAESMLSVDW-PSHAALR----YVLTG-------GDKLHHYPAEHVPFTLVN 6979
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T ++ + Q IGRP+DN +Y+LDE+ P GE+++A
Sbjct: 6980 QYGPTENAVVATAGIV--AVQAGQVTPPSIGRPIDNVQVYILDEQRQPVPIGVTGELYIA 7037
Query: 314 GANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G++LA GY RF DNP T ++YRTGD L G + + GR+D QV I
Sbjct: 7038 GSSLARGYYKRPDLTQERFVDNPF-TANRGAKMYRTGDLVRYLPDGQIEFIGRSDDQVSI 7096
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG RV+L E+E L Q P V + +VL G + +V A + G L+
Sbjct: 7097 RGFRVELGEIESVLYQHPAVKEAIVLAREDMPGVKRLAAYVVVAEDDAEQADDLRGYLKE 7156
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++++PL NGKVDR+ L
Sbjct: 7157 KLPEYMVPAAFVTLKALPLTPNGKVDRRAL 7186
>UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3;
Streptomyces|Rep: CDA peptide synthetase III -
Streptomyces coelicolor
Length = 2417
Score = 202 bits (493), Expect = 3e-50
Identities = 140/448 (31%), Positives = 219/448 (48%), Gaps = 19/448 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AYVP++P +P RI H+++DA+P+LV+ D + +E P
Sbjct: 526 VVGMLAVLKAGGAYVPVDPEYPPDRIRHMIQDADPALVLTTSDVDDRIGEECCGPLTFVM 585
Query: 80 ELAQEATS---HSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ TS HS DA+ APL A V+YTSG+TG PKGV + + A+ +
Sbjct: 586 DDPNTGTSLGRHSGTALTDADRAAPLLPGHPAYVIYTSGTTGRPKGVVVEHRAL-SAFVR 644
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILS-RETTRDPQKLVNIERL 195
R+ D + V + + +F SV + PL+ G + + R R
Sbjct: 645 HCRSSQAPDISGLSVMQASASFDQSVGSLHAPLISGGCVRLTDLRALAETAGSEPGFHRA 704
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + + + P P L L GE L E+ + + + G+ + N Y
Sbjct: 705 TFMKGTPSHLALLATMPPEVAPSGTLTL---GGEELRGEILAPWREAAGD---VTVVNVY 758
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE G + + ++ P +PIG P + +Y+LD L P GEV++AG
Sbjct: 759 GPTEATGHCLEHWIAPDRTVEPGP-VPIGTPHEGVRVYVLDSALRPVAPGLDGEVYLAGV 817
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRG 372
LA GY+G GG A RF +P R+YRTGD + G +++AGR D QVK+RG
Sbjct: 818 QLARGYLGRGGLTAERFTADPFGAPG--SRMYRTGDVAHWNEAGELVFAGRADRQVKLRG 875
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
+R++L E+E A+A PGV + V+ G+ ++ +V PG A +L +L
Sbjct: 876 YRIELGEIEAAVAGGPGVRQAAVVLREDRPGDQRLVAYVVPDPGHWDEAA-ARARLALSL 934
Query: 433 THYMMPQV-IEVESIPLLVNGKVDRQGL 459
+MMP + ++++PL NGK+DR L
Sbjct: 935 PDFMMPSAFVALDALPLSPNGKLDRAAL 962
Score = 180 bits (439), Expect = 1e-43
Identities = 169/562 (30%), Positives = 252/562 (44%), Gaps = 56/562 (9%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+A+LA KAGAAY+P++P+ P RI L DA P + + +A + ++ VP +E
Sbjct: 1601 VAVLAVAKAGAAYLPLDPAHPAERIAGTLDDAAP-VALLTTAAVAAGLPDTDVPRLLLDE 1659
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYS---AICNRLWWQ 137
A + DA+ LAPL A V+YTSG+TG PKGV +++S A+ + Q
Sbjct: 1660 EPAAGGGEDAADLTDADRLAPLLPGHPAYVIYTSGTTGRPKGVTVTHSGLPALLDIFTSQ 1719
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ-KLVNIERLV 196
P S + + F E+ LL G AL+++ T P + + V
Sbjct: 1720 LDVVPGSR----VLHHLSPAFDGGFWELAMGLLTGAALVVVEPGTVPGPALAALAVRHRV 1775
Query: 197 LVPTLLRSILMYLALG--PASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ ++L + G PA L V + ET EL + + G + N
Sbjct: 1776 THAAITPAVLQLIPEGALPAGTTL------VVAAETCPPELVARW------SAGRLMRNS 1823
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE T S L PIGRP+ + A Y+LD+ L P PGE++V G
Sbjct: 1824 YGPTETTVCATM-----SAPLAGAAVPPIGRPIADTAGYVLDDALQPVPPGVPGELYVRG 1878
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
LA GY+G A RF P P +YRTGD G + Y GRTD QVK+R
Sbjct: 1879 PGLARGYLGRPSLTAGRFVACPFG--PAGGVMYRTGDLVRHRADGDLEYLGRTDTQVKLR 1936
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G RV+ E+E A +PGV + VL G+ ++G+V GA + LR +
Sbjct: 1937 GMRVEPAEIEAVTAGLPGVAQAAVLVREDTPGDRRLVGYVVPDAGASVDPGALRQALRGS 1996
Query: 432 LTHYMMPQVIEV-ESIPLLVNGKVDRQGL-LKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P + V +++PL NGK+D + L Y + C
Sbjct: 1997 LPEYMVPAALVVLDALPLTTNGKLDHRALPAPEYRTVEGRSPRTPREEALC--------- 2047
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEISDFLGA 548
VLG G L GF++LGG+SL +I + ++R + G + + D A
Sbjct: 2048 ------RLFAEVLGLELVG---LDDGFFDLGGHSLLAIRLVERVRAELGEELGVRDLFAA 2098
Query: 549 STLGEVLSKMSTDPNGGADSKE 570
T+ ++ +++ GG + E
Sbjct: 2099 PTVADLAVRLAA--RGGREPME 2118
>UniRef50_Q8G982 Cluster: Peptide synthetase; n=102;
Cyanobacteria|Rep: Peptide synthetase - Oscillatoria
agardhii (Planktothrix agardhii)
Length = 2144
Score = 202 bits (493), Expect = 3e-50
Identities = 165/551 (29%), Positives = 261/551 (47%), Gaps = 36/551 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +LA KAG AYVP++P++P+ R+ ++L D+ S+++ S ++ ++ + E
Sbjct: 537 IIGILAILKAGGAYVPLDPTYPRDRLDYMLTDSAVSILLTQQSLVTNLRED--LDTLKIE 594
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ + + + S+++A ++YTSGSTG PKGV + ICN +
Sbjct: 595 SFCLDSDWLILENYSRENPSSSVQSENLAYLIYTSGSTGKPKGVMNLHQGICNNILRTKD 654
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLVL 197
++P ++ + + + ++L F SV +I+ L G AL+I E T+D L+ IE+ V
Sbjct: 655 SYPTTNRDRL-LQISSLAFDASVLDIFWSLSSGMALIIPKPEGTKDLAYLIQLMIEKKVS 713
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L L P R LK C GE LS EL +FF++F E L N YG
Sbjct: 714 QVFFVPSLLRLLLQQPNLENCRYLKRVFCGGEALSSELMQQFFQHFNCE----LHNLYGP 769
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE D T + + + D P I IGRP+ N IY+LD L P GE+ + G L
Sbjct: 770 TETSVDATCW--QCPPRTD-DPAIAIGRPIANTQIYILDRHLQPVPVGIVGELHIGGIPL 826
Query: 318 AAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A +F NP +LY+TGD L G + Y GR D QVK+RG R
Sbjct: 827 ARGYLNQLELTAEKFIPNPFGQ----GKLYKTGDLVRYLADGNIEYLGRIDNQVKLRGLR 882
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E++ L P +++ VV+ N ++ +V ++ A T + + L+ L
Sbjct: 883 IELGEIQTILDSHPQINQSVVIIQTDSEDNQRLVAYVDSQNQALT-PKELRQFLQPKLPA 941
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P + + PL NGKVD LK N E S
Sbjct: 942 YMIPSAFVILPEFPLNANGKVD----LKKLPQPNETALVE-------SVYVAPRNPTETI 990
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
VL A G + F+ELGG+SL +I ++K++++ G I T+
Sbjct: 991 LVNIWQEVLSLAKIG---INDNFFELGGHSLKAITLVSKIQEKMGIAFAIKQVFSHPTIA 1047
Query: 553 EVLSKMSTDPN 563
E ++ N
Sbjct: 1048 EQAGLLTETKN 1058
Score = 133 bits (321), Expect = 2e-29
Identities = 140/559 (25%), Positives = 249/559 (44%), Gaps = 54/559 (9%)
Query: 4 ICQASRDGPHFFYFSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYD--- 60
IC S +G + ++A+LA +KA Y+P+ P+ R ++ P++++
Sbjct: 1585 ICGVSLEGD----YRQVIAMLAVFKARGIYLPLRLDEPEERWQRMIVKTSPAIILIAAEN 1640
Query: 61 -DSADPSMF---KESGVPFASFEELAQ----EATSH---SADEPMDAETLAPLTSDSIAI 109
+ P + K + + +E+ Q T++ S E + + L +D
Sbjct: 1641 LEMIKPRLLVLAKPPNLLVVNHQEIQQYYEWNGTNYQEFSIVENNNRKDLLMPDADDANY 1700
Query: 110 VLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPL 169
+++TSGSTG PK + S+ ++ + + W+ F + + C+ + F + E L
Sbjct: 1701 IIFTSGSTGEPKAILGSHGSLRHFINWEKIEFGINHNWR-CLQIAQINFDPYLRETLVTL 1759
Query: 170 LHGRALLILSRETTRDPQKLV------NIERLVLVPTLLRSIL-MYLALGPASRPLRRLK 222
G L I D ++L+ I L VP+++R L + L A++ L+ L+
Sbjct: 1760 CSGGTLYIPDSIDREDLERLLLRLGEWQINLLHTVPSVMRLFLNIGRNLPNANQLLKNLQ 1819
Query: 223 LWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIP 282
+ V GE L + E+ + FGN+ + N YG++E ++ + + + Y +P
Sbjct: 1820 VLVLGGEPLFVKELCEWHEVFGNQTEF--VNIYGASETTFIKHFHRIPKPNNIS-YARVP 1876
Query: 283 IGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQ 342
G+ L + A ++DE P E GE++V L GY P+
Sbjct: 1877 GGKTLPDAAFAVIDEN-RPCAIGEVGEIFVKSPYLTKGYYQDEILTNSVFVPNPLNNGND 1935
Query: 343 RLYRTGDFGTLVKGAVL--YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGL 400
+YRTGD G L+ L R+D Q+K+ G R++L E+E A+A + GV K +V+
Sbjct: 1936 LVYRTGDLGRLLPDLTLEVIGRRSDNQIKLNGVRIELGEIEDAVAAIDGVQKALVIA--- 1992
Query: 401 DRGNPEILGFVTTKPGART-SAQHIEGKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQG 458
D+ E++ + G T + + I KL+ L YM P +I++ES PLL NGK+ R
Sbjct: 1993 DK-KEELVTVIAYYQGNNTVNREQISQKLKQVLPTYMQPTFLIQLESFPLLPNGKIHRLA 2051
Query: 459 LLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLS-LRSGFY 517
L K N + + + V G +S F+
Sbjct: 2052 LPKPEGNITQSISQPTGFN---------------QQEALLALVWGELLEIEVSDNNQSFF 2096
Query: 518 ELGGNSLNSIYTITKLRDR 536
ELGGNSL ++ ++++R++
Sbjct: 2097 ELGGNSLKAMRLVSQIRNQ 2115
>UniRef50_Q2XNF8 Cluster: Nonribosomal peptide synthetase-polyketide
synthase hybrid; n=5; Bacteria|Rep: Nonribosomal peptide
synthetase-polyketide synthase hybrid - Lysobacter
lactamgenus
Length = 5049
Score = 202 bits (492), Expect = 4e-50
Identities = 147/459 (32%), Positives = 222/459 (48%), Gaps = 29/459 (6%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F+ ++ LLA KAG AYVP++P +P+ R+ IL DA+P++ + D S+ G A
Sbjct: 1666 FAMVVGLLAVLKAGGAYVPIDPGYPRDRVAAILADADPAIALVDRVGRASL----GADAA 1721
Query: 77 SFEELAQEATSHSADEPMDAETLAP--LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
+L + A A P L++ ++A V+YTSGSTG PKGV+ + + NRL
Sbjct: 1722 GARDLLDLDAADPAWSDRSAADPEPAGLSARNLAYVIYTSGSTGTPKGVQNEHRGVVNRL 1781
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-- 192
W + + + + KT+ F SV E + PLLHG L + + +DP L+ +
Sbjct: 1782 AWMPEEYRLGAGDTV-LQKTSFGFDVSVWEFFWPLLHGATLALAPPDAHKDPAALIELIV 1840
Query: 193 -ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
R+ V + + ++L R L+ +CSGE L K +
Sbjct: 1841 RHRVTTVHFVPSMLAVFLQADGVER-CAGLRRVICSGEALPGASVRLLHKRLPQT---AI 1896
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE + T + D T+PIGRP+ N IYLLD P GE++
Sbjct: 1897 HNLYGPTEAAIEATAWTCPRDFAGD---TVPIGRPIANARIYLLDPRRQPVPLGAVGELY 1953
Query: 312 VAGANLAAGYVGGGGA--NRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
+ G +A GY+ RF +P A P+ R+YR+GD L G + + GR D QV
Sbjct: 1954 IGGVGVARGYLNRPELTDERFLPDPFAADPD-ARMYRSGDLARHLAGGDIEFLGRNDHQV 2012
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG---ARTSAQHIE 425
K+RG R++L E+E LA V + VVL G + V + G AR A
Sbjct: 2013 KLRGFRIELGEIETRLAAHAEVRETVVLALGEGSLMRLVAYVVAAQRGDERAREPASEFG 2072
Query: 426 GKLR----SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+LR +AL YM+P + ++++PL +GK+DR+ L
Sbjct: 2073 ARLRAHLAAALPEYMIPAAFVALDALPLTPSGKLDRRAL 2111
Score = 193 bits (470), Expect = 2e-47
Identities = 149/456 (32%), Positives = 221/456 (48%), Gaps = 25/456 (5%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F+ I+ LLA KAGAAYVP +P++ R IL DA P LV+ D A +MF E +
Sbjct: 2742 FALIVGLLAVLKAGAAYVPFDPAYSSERAAQILADAAPKLVL-ADRAGRAMFGEQALRDR 2800
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+L Q+ + + + E A L S +A ++YTSGSTG PKGV + + +C +
Sbjct: 2801 GVLDLEQDQSLWFDRQGNNPEP-AGLHSGRLAYLIYTSGSTGTPKGVMIEHRNVCALIAA 2859
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+ S + I + + +F SV EI+ L G L++ + V
Sbjct: 2860 LQSVYSLSAQDRILQFSSP-SFDASVEEIFATLATGATLVLRNDAWLESSAAFVERCARH 2918
Query: 197 LVPTLLRSILMYLALGPA---SRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ L S + L A + L +L+ V GE ++ +F + G +L N
Sbjct: 2919 EITGLSLSTSFWAQLADAWSDLKALPKLRQIVMGGEAVAAHALKRWFD--DAQAGPELLN 2976
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D T + L SD P IGRPL N YLLD P GE+++A
Sbjct: 2977 AYGPTETTVDATLHRLRASD-----PVPSIGRPLANTRAYLLDRFGQPVPLGAVGELFLA 3031
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKI 370
GA + GY+ A RF +P PE R+YRTGD L G + + GR D Q+K+
Sbjct: 3032 GACVGRGYLNRPELTAERFLADPFVADPE-ARMYRTGDLVRYLADGTLEFLGRNDHQIKL 3090
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS------AQHI 424
RG R++L E+E LA P V + VVL G D G+ ++ +V G R + A +
Sbjct: 3091 RGFRIELGEIEARLAAHPAVREAVVLALGED-GDKRLVAYVVADDGERAAAAPSALAADL 3149
Query: 425 EGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L + L YM+P + ++++P+ V+GK+DR+ L
Sbjct: 3150 RAHLAAVLPGYMVPAAFVALDALPMTVSGKLDRKAL 3185
Score = 148 bits (359), Expect = 5e-34
Identities = 124/451 (27%), Positives = 205/451 (45%), Gaps = 30/451 (6%)
Query: 22 ALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEEL 81
A+LA KAG AYVP++P R+ +L DA+P+LV+ D+A E+ + + +L
Sbjct: 608 AVLAVLKAGGAYVPLDPDDAPARLRELLADADPTLVL-SDAAGRRALGENALLAHAVVDL 666
Query: 82 AQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTF 141
+ + D A L+ +A +Y +G+T P G + + A+ +RL W +
Sbjct: 667 DERRPVWAGASTADPRP-AGLSPRHLACAIYPAGATAAPAGAQNEHRALVDRLRWMQDAY 725
Query: 142 PYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLVLV 198
E + V +T+L ++ E++ +G +++ P LV + +
Sbjct: 726 RLGAGETV-VQQTSLAADAALWELFWTWSNGATVVLAPAGAQSTPAALVELFVRHDIATA 784
Query: 199 PTLLRSILMYLALGPASR--PLRRLKLWVCSGETL---SKELASEFFKYFGNEDGYKLAN 253
++ +L R LRRL +CSGE L S LA + + +
Sbjct: 785 HFAPAALAAFLRADGVERCVGLRRL---ICSGEALSGASLRLAQQRLPWAA------IHR 835
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG E D T + D PIGRP+ N +YLLD P GE+ +
Sbjct: 836 LYGPAETAMDATAWTCPPDFAGD---RAPIGRPIANTRVYLLDRHRRPLPPGAVGELHIG 892
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
GA + GY+ A RF +P A P R+YR+G+ G + GR+D Q+++
Sbjct: 893 GAGIGRGYLNRPELTAERFVPDPFAADPA-ARMYRSGERARYRPDGELECLGRSDRQLRL 951
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIEGKLR 429
RG R++ ++E LA+ P V + VVL G D ++ ++ +PG A + + L
Sbjct: 952 RGLRIEPGDIEARLAEHPAVQRAVVLAPG-DGERKRLVAYLVVRPGHAGDLSAELRAFLA 1010
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
S L YM P + ++++PL G++DR L
Sbjct: 1011 STLPDYMTPAAFVMLDALPLTSRGELDRDAL 1041
>UniRef50_A4F9A3 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Putative
non-ribosomal peptide synthetase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 1767
Score = 202 bits (492), Expect = 4e-50
Identities = 164/527 (31%), Positives = 251/527 (47%), Gaps = 43/527 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAGAAY+P++P P RI HI+ DA P+ V+ D+ S S + +
Sbjct: 436 VVALLAVLKAGAAYLPLDPGHPAERIAHIVADARPA-VLVSDTEHASRLLPSDITRLLLD 494
Query: 80 E--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ A+ ++HS +P E + D+ A V+YTSGSTG PKGV + + + RL+
Sbjct: 495 DPATAEAISAHSQRDPGPGER-GRVGPDNAAYVIYTSGSTGRPKGVVIPHRNVV-RLF-- 550
Query: 138 FRTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
T P+ ++ VW + F SV E+WG LLHG L+++ E +R P + + +
Sbjct: 551 TATEPWFSFDDTDVWTLFHSYAFDFSVWELWGALLHGGRLVVVPHEVSRSPGEFLELLER 610
Query: 196 VLVPTLLRSILMYLALGPASRPL---RRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
V L ++ + L A R L+ V GE L ++++ L
Sbjct: 611 ERVTVLNQTPSAFYQLVQADREACAELALRYVVFGGEALELSRLDDWYRRHPRNP--VLV 668
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE V++ L+ +Q IGR + + +Y+L ++L P GE++V
Sbjct: 669 NMYGITETTVHVSHLELD-REQAARREGSLIGRGIPDLRVYVLADDLEPVPPGVVGEMYV 727
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
AG LA GY+G G A RF +PH R+YRTGD G + +AGR D QVK
Sbjct: 728 AGEGLARGYLGRRGLTAQRFVADPHGRAG--TRMYRTGDLAKWRADGTLEFAGRADHQVK 785
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG R++ E+E LA PGV + V+ G+ ++G+ T +H L
Sbjct: 786 IRGFRIEPGEIEANLAAHPGVRQAAVVVREDRPGDRRLVGYAVTDAEPARLREH----LA 841
Query: 430 SALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
+ L YM+P ++ V+ IPL NGK+D L D++
Sbjct: 842 AVLPDYMVPSALVVVDEIPLTGNGKLDTAALPAPEVEAGGRGPRN---DVE--------- 889
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
VLG G + + GF+ELGG+SL + ++++RD
Sbjct: 890 ---ARLCALFAEVLG---VGEVGIDDGFFELGGHSLLATRLLSRVRD 930
Score = 57.6 bits (133), Expect = 1e-06
Identities = 40/116 (34%), Positives = 62/116 (53%), Gaps = 17/116 (14%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ L+A +GAAY+ ++P +P R+ H+++DA P++VI D +
Sbjct: 1490 VVGLVAAMTSGAAYLALDPDYPAERLRHMVEDARPAVVI-TGGRDTDL------------ 1536
Query: 80 ELAQEATSHSADEPMD-AETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
LA+ H DEP D + L ++ A V+YTSGSTG PKGV + +S I L
Sbjct: 1537 -LARVLGCH--DEPADPSGPLPEPAAEDPAYVIYTSGSTGRPKGVVVPHSGISGLL 1589
>UniRef50_Q094I7 Cluster: Aminotransferase, class III family; n=9;
cellular organisms|Rep: Aminotransferase, class III
family - Stigmatella aurantiaca DW4/3-1
Length = 3433
Score = 201 bits (491), Expect = 5e-50
Identities = 148/452 (32%), Positives = 232/452 (51%), Gaps = 32/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL K+GAAYVP++PSFP R+ H+L + SL++ + E GV +
Sbjct: 2592 VIGLLGILKSGAAYVPLDPSFPAERLAHMLDHSRLSLLLAHGKT-AGVLPERGVRRLLLD 2650
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E A +SHS++ P ++ +A V+YTSGSTG PKG+++ + A+ N L R
Sbjct: 2651 EHAA-LSSHSSENPEGGAG-----AEDVAYVMYTSGSTGTPKGIQVLHGAVTNLLE-SIR 2703
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
++ + T ++F + E++ PLL G L + ET D ++L E VP
Sbjct: 2704 DLLGPSDRDVLLAVTTISFDIAALELYLPLLVGARLAVADHETVADGERLKQ-EMARRVP 2762
Query: 200 TLLRSI----LMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
TL+++ M + G P +L + +C GE L KEL+++ G +L N Y
Sbjct: 2763 TLMQATPATWRMLIEAGWEGDP--KLDI-LCGGEALRKELSAQLLPR-----GKRLWNLY 2814
Query: 256 GSTEVMGDVTYYVLE----GSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
G TE + + ++ G+++ D + P+G+PL N +Y+L L P GE++
Sbjct: 2815 GPTETTIWSSAHRVQASPHGAERADA--SEPLGQPLANTQLYVLSPALQPVPLGVTGELF 2872
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+ G LA Y+G A +F +P + QP RLYRTGD G + + GRTD QV
Sbjct: 2873 IGGMGLAQSYLGQPSLTAEKFVPDPFSGQPG-ARLYRTGDLVRYRPDGTLEFFGRTDFQV 2931
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG R++L +E ALAQ P V ++ + G+ + +V + + + L
Sbjct: 2932 KIRGFRIELGAIEAALAQHPAVANVALIAREVKPGDSRLFAYVVFQREQAVPPEALAEFL 2991
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+S L YM+P +I VE +PL NGKVDR+ L
Sbjct: 2992 QSKLPGYMVPGAIIPVEELPLTPNGKVDRKAL 3023
>UniRef50_Q4U445 Cluster: DszC; n=3; Proteobacteria|Rep: DszC -
Polyangium cellulosum (Sorangium cellulosum)
Length = 3795
Score = 201 bits (490), Expect = 7e-50
Identities = 167/604 (27%), Positives = 267/604 (44%), Gaps = 31/604 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AYVP++P++P+ RI I +DA S+++ + + +P
Sbjct: 1056 VVALLAILKAGGAYVPIDPTYPRERIDFIAEDAGLSVLLLAE-------ERRRLPSFRGT 1108
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L H D + + D +A V+YTSGSTG PKG + + AICNRL W
Sbjct: 1109 QLCLSTERHLLDGEAEHDLGPTAGPDHLAYVIYTSGSTGKPKGCMIPHDAICNRLLWMQD 1168
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ + + + + KT TF SV E + PL+ G L++ E +D LV + E+ +
Sbjct: 1169 EYRLAPDDRV-LQKTPYTFDVSVWEFFLPLIAGATLVMARPEGHKDVAYLVRVMEEQRIT 1227
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L + PA L+ SGE LS ++ F + +L N YG
Sbjct: 1228 TCHFVPSMLNFFLKEPALPT--HLRQVFTSGEALSYDVMDTFLR----RSPARLHNLYGP 1281
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVTY+ E +PIGR + N I++LD L P G++++ G L
Sbjct: 1282 TEAAVDVTYWPCERRPDRK----VPIGRAISNVEIHILDSALRPVPAGAEGDLYIGGVCL 1337
Query: 318 AAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIRGHRVD 376
A GY+ +R P P RLY TGD TL G + Y GR DAQVK+RG R++
Sbjct: 1338 ARGYLNRPELSRERFVPSPFDPG-ARLYNTGDRARTLDDGNIEYLGRLDAQVKLRGFRIE 1396
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L E+E AL+ V VV +P+++ ++ T + ++ L+ L YM
Sbjct: 1397 LGEIEAALSAHEAVQDAVVAVQDAHTEDPKLVAYLVTGGRPFPAPGALKAYLKERLPDYM 1456
Query: 437 MP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDD----AEVAVDIDCSXXXXXXXXXX 491
+P + + IP+ +GK+DR+ L + + A +
Sbjct: 1457 VPNRFAPIAQIPVTAHGKLDRKALPWPVPAPSAQPEPPPAGAAAAPPGAAQARRPAGVSR 1516
Query: 492 XXXXXTVGAVLGRAARGT-LSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGAS 549
+ +LG+A T L + +ELG SL + + +R G + + L
Sbjct: 1517 EAAEEELQRILGKALHLTRLDPGADLFELGATSLTIVQASQHIEERFGVGLPVEVVLAEP 1576
Query: 550 TLGEVLSKMSTDPNGGADSKEATFTAV--PMRDEHKKEVIDMVESSFYEKAELEQFLKHE 607
TL + ++ GA A A+ P F+ + + E+F + +
Sbjct: 1577 TLDAIARHVAERTAAGAPEPPAPGPALDAPPAAPEPPAAAAPGPIDFFSREDRERFKQQQ 1636
Query: 608 IETR 611
+ R
Sbjct: 1637 LHLR 1640
>UniRef50_Q0SE34 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 4903
Score = 201 bits (490), Expect = 7e-50
Identities = 151/451 (33%), Positives = 222/451 (49%), Gaps = 31/451 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL A KAG AY+PM+P P GR ++ A P+LV+ S + ++ GV +
Sbjct: 2024 LVALHAVLKAGGAYLPMDPEHPLGRTALVIDSAAPALVLTSGSHNRAV--PHGVAVVDLD 2081
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + T + A ++E APL + A V+YTSGSTG PKGV +++ + N+ W
Sbjct: 2082 LL--DLTGYDARSITNSERRAPLHPANAAYVIYTSGSTGRPKGVTVTHEMMVNQFRWAQT 2139
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
P S+ + + KT LTF S E+ PL G ++I + + RDP+ L +I
Sbjct: 2140 LTPLDGSDAV-LHKTPLTFDISAWELLWPLHTGARVVIAAPDGHRDPRYLARMVAQESIT 2198
Query: 194 RLVLVPTLLRSILMYLALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L +VP++L + L GP PLRR+ +GE LS AS F + L
Sbjct: 2199 TLHVVPSMLDAFLEQC--GPRELAPLRRV---YSAGEPLSAATASRFEE----RSAAALY 2249
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N+YG E + E D + ++ IGRP+ N Y+LD L P GE+++
Sbjct: 2250 NWYGPCEAAAATS----ESLDGNEFGTSVAIGRPIHNIRTYVLDSRLRPVPVGTRGELYL 2305
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVK 369
AGA LA GY G A RF +P R+YRTGD + G + Y GRTD Q+K
Sbjct: 2306 AGAYLARGYAGRPDLTAERFVADPFGETGG--RMYRTGDVVRWNESGRLEYLGRTDFQIK 2363
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG RV+ E+E AL P V V + ++ +V G + I +L
Sbjct: 2364 LRGQRVEPGEIESALTSDPAVTHAAVTVHRDAEAGDRLIAYVVAADGVPPDERRIVDRLA 2423
Query: 430 SALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
L YM+P V+ + ++PL +GK+DR L
Sbjct: 2424 GLLPAYMIPSAVVPLPALPLTTSGKLDRAAL 2454
Score = 194 bits (472), Expect = 1e-47
Identities = 164/575 (28%), Positives = 259/575 (45%), Gaps = 39/575 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A AG AYVP++P P R +++ + +V+ + + F S V A
Sbjct: 4120 LVGMYAVATAGGAYVPIDPDQPGQRNAQVIRSSATRVVL---TTERDRFDLSDVLPAETR 4176
Query: 80 ELAQEATSHSADEPM---DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ + S +P D + +APL + A V++TSGSTG PKGV ++++A+ + L W
Sbjct: 4177 LVVIDRVDLSGVDPSPISDLDRIAPLLAQHPAYVIHTSGSTGTPKGVVVTHAAVVSFLSW 4236
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERL 195
+ T P + + + K TF SV E W PL+ G ++I + RDP+ L I R
Sbjct: 4237 RQDTDPLGADDTVML-KLQYTFDASVREFWWPLIAGARMVIARPDGHRDPRHLAELIGRH 4295
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ +++ L L L+ C GE L A + Y N Y
Sbjct: 4296 RVTAGYFLPLMLAEILAIPEADLTSLRQVSCGGEVLPPGTAHSVHARCPDAVLY---NEY 4352
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE VT V+ G++ T+PIG P + + +LD L P PGE+++AGA
Sbjct: 4353 GPTETAVAVTRTVV-GTEAA----TVPIGVPQNGVGVLVLDSRLHPVPIGVPGELYLAGA 4407
Query: 316 NLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRG 372
LA GY+G GA RF NP P QR+YRTGD + + G + Y GR D QVKIRG
Sbjct: 4408 QLARGYLGQPGATAARFPANPWG--PPGQRMYRTGDVVSRRRDGTIDYLGRRDLQVKIRG 4465
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
RV+L E+E AL + V + Y ++G+V P + + +L L
Sbjct: 4466 QRVELEEIETALRRHAAVAQSAAAVYESAGTGARLVGYVVPHPDMVVDTRAVSAELAQRL 4525
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P Q++ + ++P +GK+DR+ L D V
Sbjct: 4526 PRYMVPNQIVVLGALPSTPHGKLDRRAL----------PDPGVP---RAQRFRPPTTRTE 4572
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEISDFLGAST 550
VLG G + L F+ELGGNSL++ ++L V + F +T
Sbjct: 4573 KLVTAVFADVLG---TGLVGLDDNFFELGGNSLSATRAASRLHTSTRVEVRLDWFFADAT 4629
Query: 551 LGEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKE 585
+ +++S+ + + +P+ + +E
Sbjct: 4630 AESIAARISSSFAAASAASAGLGVLLPLHPDGGRE 4664
Score = 144 bits (350), Expect = 6e-33
Identities = 128/450 (28%), Positives = 213/450 (47%), Gaps = 31/450 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++++ A K GAA+VP++P +P R+ +++ D+ L + +AD + G +
Sbjct: 3069 SVVSVWAVAKTGAAFVPVDPHYPAARVRYLMDDSGAVLGL-TTAADREALPD-GTDWLLL 3126
Query: 79 EE--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
++ E +S+ DA+ PL + A V+YTSGSTG PKGV ++++ + +
Sbjct: 3127 DDPDFRTECRGYSSAPVTDADRARPLDARHPAYVIYTSGSTGNPKGVVVTHTGLADFTAE 3186
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
Q + + S + ++ +F SV EI L G A ++L+ + +L ++
Sbjct: 3187 QRERYSVTASSRT-LHASSPSFDGSVLEILLALGAG-ACMVLAPPAVQADDQLTDLLARE 3244
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + + + + P R L L++ V GE EL + + E Y N YG
Sbjct: 3245 RVSHVFTTPTVLATVDP--RGLHDLRVVVAGGEPCPPELVAV---WAAQEQMY---NGYG 3296
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T + SD + + IGRP+ A+ LLD L P GE++++G
Sbjct: 3297 PTE-----TTVMTSISDPMAAGGPVTIGRPIRGAAVLLLDSRLHPVPTGVAGELYISGPG 3351
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
+A GY A RF +P E R+YRTGD G + G++ Y R D+Q+++RG
Sbjct: 3352 VARGYHRRPALTAARFVASPFGASGE--RMYRTGDVGRWRRDGSIEYLHRNDSQIELRGV 3409
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E++ L P V L G ++ +V AR + +R A T
Sbjct: 3410 RIELGEIDATLLAHPTVRFAATDVRELRDGVDALVSYVVP---ARNETVDPDQLIRFAAT 3466
Query: 434 HYMMPQ----VIEVESIPLLVNGKVDRQGL 459
MP V+ V+++PL VNGK+DR L
Sbjct: 3467 RLPMPLVPAIVVVVDAVPLTVNGKLDRSAL 3496
Score = 120 bits (288), Expect = 2e-25
Identities = 132/450 (29%), Positives = 207/450 (46%), Gaps = 46/450 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+ A K GAA++P++P++P R+ H+L D+ ++ + SA+ + + +
Sbjct: 528 VCAVWAVAKTGAAFLPVDPTYPVSRVRHMLGDSHAAVGL--TSAEYTNTLPDSTEWLLLD 585
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E S+ D P L D A ++YTSGSTG+PKGV +++ I N + Q R
Sbjct: 586 E---SGGSNVHDFPTPTIRL-----DDAAYLVYTSGSTGVPKGVVVTHRGIANLVSAQ-R 636
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP--QKLVNIERL-- 195
T DS + + +F SV E+ G AL+I +L+ ER+
Sbjct: 637 TRLDLDSAARVLHVASPSFDASVFEMLMAFGSGAALVIAPPAVFGGSPLARLMTTERVTH 696
Query: 196 -VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
V+ P++L S + P + L+ V +GE EL S + D Y A
Sbjct: 697 AVITPSVLAS------MDPGE--VGGLRTLVVAGEKCPPELVSRWASRCRMIDAYGPA-- 746
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
T VM V S+ L + +GRP+ +LD L P GE++VAG
Sbjct: 747 --ETTVMATV-------SEPLAEPGPVTVGRPIRGARAVVLDHRLRPVPVGVVGELYVAG 797
Query: 315 ANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIR 371
LA GY + RF +P+ P R+YRTGD L Y GR+D QV +R
Sbjct: 798 TALARGYHRNARQTSERFVADPYG--PPGTRMYRTGDTVRWTYDHELEYLGRSDEQVNLR 855
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART-SAQHIEGKLRS 430
G RV+ E++ L + P V V + G+ +++ +V GA T + Q + L +
Sbjct: 856 GLRVEPGEIDATLLRYPAVRFAVTVIRSRGAGD-QLVSYVV---GADTVTEQDLLSFLST 911
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +++P V+ + IPL +GK+DR L
Sbjct: 912 ELPPHLVPAAVVVLPDIPLTPSGKLDRTAL 941
>UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosomal peptide
synthetase - Streptomyces avermitilis
Length = 3686
Score = 200 bits (489), Expect = 9e-50
Identities = 165/568 (29%), Positives = 265/568 (46%), Gaps = 38/568 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I ALL K+GAAY+P++P+ P RI +I+ DA+ +V+ + +F E
Sbjct: 552 IPALLGILKSGAAYLPLDPANPADRIAYIVGDAQAPVVV-TTAEHAHLF--------DVE 602
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + D++ P + +++ +YTSGSTG PKGV L+++ + L
Sbjct: 603 LLLLDTDAPDLAARPDSDPGVPGSPENLIYTIYTSGSTGRPKGVALTHTNVVRLLERGNE 662
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
+ ++D++ VW + F SV E+WG LLHG L+++ + TR P++ +++
Sbjct: 663 HYAFTDTD---VWPLFHSYAFDVSVWEMWGALLHGGRLIVVPYDVTRSPEEFLDLLVRER 719
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V L ++ + +L A L L+ V +GE L + FG D L N YG
Sbjct: 720 VTVLNQTPSAFRSLVAADAELS-LRAVVFAGEKLEISELRPWADRFGL-DRIALVNMYGI 777
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE TY+ L D LD +G PL + +YLLD + PGE+ V G +
Sbjct: 778 TETTVHTTYHRLTERD-LDPRAGNAVGHPLADLRVYLLDADRQLVPVGVPGEIHVGGPGV 836
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF +P+ P RLY++GD L G++ + GR D QVKIRG R
Sbjct: 837 ARGYLNRPELTAERFVPDPYG--PAGSRLYKSGDLARRLPDGSLEFLGRIDDQVKIRGFR 894
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E ALA P V VVL G+ ++ + T + + L + L
Sbjct: 895 IELGEIETALAAHPQVRDAVVLVREDTPGDKRLVAYTTPAADQAPAPGDLRSHLAARLPE 954
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P + ++++PL NGK+D++ L DA + +
Sbjct: 955 YMVPAAFVALDALPLTTNGKLDKRAL------PAPGQDA-----LGAAGHVAPRTVAEER 1003
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
VLG G + GF+ELGG+S+ ++ + +LR GY + + D T+
Sbjct: 1004 IAEVWADVLGLDRVG---VEDGFFELGGHSIRAVTLVGRLRAIGYDLAVRDVFEYRTVAR 1060
Query: 554 VLSKMSTDP-NGGADSKEATFTAVPMRD 580
V ++ P AD + F+ + D
Sbjct: 1061 VAELVTGRPAPEDADRRTEPFSLLTAED 1088
Score = 182 bits (444), Expect = 2e-44
Identities = 164/556 (29%), Positives = 251/556 (45%), Gaps = 44/556 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I ALLA WKAG AYVP++PS+P R+ I+ + ++ + +A F G +
Sbjct: 2637 IAALLAVWKAGGAYVPVDPSYPAERVASIVGTSGAAVAV-TSAAYADRF---GAVSLLLD 2692
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ ++ ++ + P A+ L D +A V++TSGSTG PKGV + + + + W R
Sbjct: 2693 D--EDVSALPSAAPARADDL-----DQLAYVIFTSGSTGRPKGVEVPHRGLAGHVGWAAR 2745
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ ++ +++ F V +W PL+ G+ + + ++T +P +L + L P
Sbjct: 2746 ELASRGTGGAPLF-SSVAFDLIVPNLWAPLVTGQRVFAVPQDT--EPAELGH-RLLAGAP 2801
Query: 200 ----TLLRSILMYLALGPASRPLRRL-KLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
L L LA + + L ++ V +GE L A G +L N
Sbjct: 2802 YSFVKLTPGHLDLLAEQLTTEQAQELAEVMVVAGEALPGATADRSLDILGPG---RLINE 2858
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE T + + D+ +PIGRPL N +Y+LD L P GE++V G
Sbjct: 2859 YGPTEASVGTTVFPVLAPVGRDV---VPIGRPLPNMRVYVLDSALQPVPVGVTGELYVGG 2915
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
+A GY G A RF +P+A +P RLYRTGD L G V + GR D QVKIR
Sbjct: 2916 TGVARGYAGRPDLTAERFLPDPYAAEPG-ARLYRTGDLVRHLPDGNVEFLGRVDDQVKIR 2974
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G+RV+L EV+ LA+ P V V + G+ ++G+ T GA + +
Sbjct: 2975 GYRVELGEVQAVLAEHPAVRDAFVTVHEPVPGDRRLVGYWTPAAGAGARPEELAAHCAVR 3034
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L YM+P + +E++PL NGKVDR L + A V
Sbjct: 3035 LPDYMVPSAFVALEALPLNANGKVDRGVLPVPGRGALRSGTAHVP----------PRTPT 3084
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
VLG G + F++LGG+SL I + R G V + T
Sbjct: 3085 EKALGAIWSEVLGVEEIG---VHDRFFDLGGHSLLMIKVLAAARAAGLAVSVYRMYQHDT 3141
Query: 551 LGEVLSKMSTDPNGGA 566
L ++ + + D GA
Sbjct: 3142 LIDLAAAVDEDTAAGA 3157
Score = 179 bits (436), Expect = 2e-43
Identities = 165/571 (28%), Positives = 254/571 (44%), Gaps = 69/571 (12%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ALLA WKAG AYVP++PS+P R+T +M + SG P E
Sbjct: 1607 LTALLAVWKAGGAYVPVDPSYPADRVT-------------------AMRELSGAPVTLTE 1647
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ S P + L D +A V++TSGSTG PKGV +++ + N + W R
Sbjct: 1648 IPVRALISLPTGAPARTDDL-----DRLAYVIFTSGSTGTPKGVEVTHRGLANHVAWAAR 1702
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP--QKLVN---IER 194
S + +++ F V +W PL+ G+A+ +S++ + LV
Sbjct: 1703 ELA-SQGDGGAPLFSSVAFDLVVPNLWAPLVTGQAVHTVSQDVDMADLGEHLVASGPYSF 1761
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ L P L + LA A+ L V +GE ++ ++ +L N
Sbjct: 1762 IKLTPGHLDVLAQQLAPEQAAALAPVL---VVAGEAFTRATLE---RWRALAPDTRLINE 1815
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE T + + + D+ +PIGRPL N +Y+LD L P GE++V G
Sbjct: 1816 YGPTEASVGTTVHEVPRDAETDV---LPIGRPLPNMRVYVLDPALQPVPVGVTGELYVGG 1872
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIR 371
+A GY G A RF +P+ T+P R+YRTGD G V + GR D QVKIR
Sbjct: 1873 TGIARGYAGRPDLTAERFLPDPYGTEPG-ARVYRTGDLVRQRPDGNVEFLGRVDDQVKIR 1931
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G+RV+L E++ L PG+ V + E+ G+ A A+ + L
Sbjct: 1932 GYRVELGEIQAVLTAHPGIRDAFVTTV-----DGELAGYY-----APAGAEGVREHLADR 1981
Query: 432 LTHYMMPQVI-EVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L YM+P + ++++PL NGK+DR+ L + +DD VA D
Sbjct: 1982 LPDYMVPATLTALDALPLNANGKIDRKA-LPAPDAAAADDDGYVAPRTD----------T 2030
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
VLG G + GF+E+GG+S+ ++ + LR G+ + + D T
Sbjct: 2031 EERIAAVWAQVLGLERVG---VEDGFFEIGGHSIRAVALVGALRSAGFDIGVRDVFEHRT 2087
Query: 551 LGEVLSKMSTDP-NGGADSKEATFTAVPMRD 580
+ + ++ P D+ A F VP D
Sbjct: 2088 VAALGEHLTGRPARTEVDTPVARFALVPAED 2118
>UniRef50_Q8G983 Cluster: Peptide synthetase; n=118; cellular
organisms|Rep: Peptide synthetase - Oscillatoria
agardhii (Planktothrix agardhii)
Length = 2816
Score = 200 bits (489), Expect = 9e-50
Identities = 143/415 (34%), Positives = 215/415 (51%), Gaps = 34/415 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++P +PQ R+T++L D + +++ S S+ + A
Sbjct: 319 VVGLLAILKAGGAYVPIDPHYPQERLTYLLADTQVKILLTSQSLT-SLLPAN---LAKII 374
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + + P + E+ +T +++A V+YTSGSTG PKG + + NRL W
Sbjct: 375 CLDSDWDLIAKENPDNFES--GVTVENLAYVIYTSGSTGQPKGAMNCHRGVVNRLLWMQD 432
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
T+P + + I + KT +F SV E + PLL G L++ E +D L+ I
Sbjct: 433 TYPLTQGDRI-LQKTPFSFDVSVWEFFCPLLTGARLVVAKPEGHKDSVYLIKLIQDQQIT 491
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++LR +L L + LK +CSGE L +L+ FF+ F E L N
Sbjct: 492 TLHFVPSMLRVLLQEADL----EKCQSLKRVICSGEALPNDLSQRFFERFNCE----LHN 543
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVTY+ + + ++ +PIGRP+ N IYLL+ +L P GE+ +
Sbjct: 544 LYGPTEAAIDVTYWACSPNWKREV---VPIGRPVANTQIYLLNADLQPVPIGVVGELHIG 600
Query: 314 GANLAAGYVGGGG--ANRFCDNPH--ATQPE-----FQRLYRTGDFGT-LVKGAVLYAGR 363
G LA GY A +F NP + Q E RLY+TGD L G + + GR
Sbjct: 601 GVQLARGYFNRPELTAEKFIANPFYPSLQKEQGSTISPRLYKTGDLARYLPDGNIEFLGR 660
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR 418
D QVKIRG R++L E+E L Q P V + VVL + + G+ ++ +V ++ R
Sbjct: 661 LDHQVKIRGFRIELGEIETILGQHPDVCQSVVLAHQTETGSQTLIAYVVSQSQTR 715
Score = 165 bits (402), Expect = 3e-39
Identities = 159/568 (27%), Positives = 259/568 (45%), Gaps = 45/568 (7%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
S ++ LL KAG AYVP++P +P R+ IL D++ +++ + + SG
Sbjct: 1806 SLVVGLLGILKAGGAYVPLDPHYPTERLELILTDSQVPVLLTQQTLLSHLSHYSGDRVV- 1864
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
L ++A A +P + ++S + V+YTSGSTG PKGV + + + L W
Sbjct: 1865 ---LDRDAAI-IAQQPK-TNPKSQVSSSNSVYVIYTSGSTGKPKGVVIEHRSTVTLLDWA 1919
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
F + + + T++ F SV E++ PL G A+ IL+ P L + L
Sbjct: 1920 RTVFSFDELAGVLA-STSVCFDLSVFELFLPLTVGGAV-ILADNALALPN-LAAATEVTL 1976
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ T+ +I LAL + +R + L +GE LS L + ++ E Y N YG
Sbjct: 1977 INTVPTAIAQLLALEAIPQSVRTVNL---AGEPLSNSLVQKLYQLPQIERVY---NLYGP 2030
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
+E T+ +E P+I GRP+ + +YLL+ P GE+++ GA L
Sbjct: 2031 SEDTSYSTFSCIEKGATTQ--PSI--GRPIAHSQVYLLNATHQPVPLGTIGELYMGGAGL 2086
Query: 318 AAGYVGGGG--ANRFCDNP-HATQPEFQ------RLYRTGDFGTL-VKGAVLYAGRTDAQ 367
A GY+ A +F NP H+ ++Q +LY+TGD G + + GR+D Q
Sbjct: 2087 ARGYLHRPELTAEKFIANPFHSPLQKYQGLSPSPKLYKTGDLARYRPDGNLEFLGRSDYQ 2146
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
+K+RG R++L E+E L PGV + VVL G +++ +V ++ T+ Q +
Sbjct: 2147 IKLRGFRIELGEIEVVLENCPGVKQAVVLRREDLVGGAKLVAYVVSENSTLTT-QDLRRF 2205
Query: 428 LRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L L YM+P + +ES PL NGKV+R L + + E+ D D +
Sbjct: 2206 LEQQLPDYMIPGFFVPLESFPLTPNGKVNRPALPR--------PEMELIPDGDFAAPQTA 2257
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
V + + RG F+ELGG+S+ S+ + + R G +
Sbjct: 2258 QEQILATIWQNVLGI-QQVGRG-----DRFFELGGDSILSLQVVAQARQAGLKITPRQIF 2311
Query: 547 GASTLGEVLSKMSTDPNGGADSKEATFT 574
+L E+ + D G + T T
Sbjct: 2312 RYPSLAELAACCDIDSIGDTPNFSRTLT 2339
Score = 43.6 bits (98), Expect = 0.021
Identities = 39/150 (26%), Positives = 61/150 (40%), Gaps = 14/150 (9%)
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L + L YM+P + + IPL NGK+DR+ L + D VA C+
Sbjct: 1141 LETRLPEYMIPNAFVLLAEIPLTPNGKLDRRALPSPEQIRLELTDTFVA---PCTPIEEM 1197
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
+LG G + F+ELGG+S+ I I K R G+ + + L
Sbjct: 1198 LALIWAE-------ILGLEQIG---IHDNFFELGGDSIRGIQVIAKARTMGFEFSLPELL 1247
Query: 547 GASTLGEVLSKMSTDPNGGADSKEATFTAV 576
T+ E+ +S + N K F+ +
Sbjct: 1248 QHQTIQELAHLVSRELNPVTSQKTEVFSLI 1277
>UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Myxococcus xanthus (strain DK 1622)
Length = 4567
Score = 200 bits (489), Expect = 9e-50
Identities = 165/541 (30%), Positives = 256/541 (47%), Gaps = 32/541 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++ +P RI+ +L++A S+ + +S + G+
Sbjct: 2702 VVGLLAILKAGGAYVPIDHHYPAERISLLLQEAGVSVFVTQESLADELPSSGGLMVC--- 2758
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A P A A + D +A V++TSGSTG PKGV + + A+ +RL
Sbjct: 2759 --VDTDADLIAALPHGAPPSADVGGDDLAYVMFTSGSTGRPKGVCIPHRAV-SRLVLA-N 2814
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + +E+ + + F S E+WG LLHG A L+L+ T +L + V
Sbjct: 2815 PFIHFGPDEVFLQLAPVAFDASTLELWGALLHG-ARLVLAPPHTPSLDELAALLTHHRVS 2873
Query: 200 TL-LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
TL L + L + L ++ + G+ L + + G L N YG T
Sbjct: 2874 TLWLTAALFEQMVLHQGNALAGVRQVLAGGDVLPPLRVRQHLERIPL--GAVLVNGYGPT 2931
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + L + ++PIGRPL + Y+LD + P PGE++V G LA
Sbjct: 2932 ENTTFSATHSLRAGEAFGT--SVPIGRPLGHSTAYVLDSRMEPVPVGVPGELFVGGDGLA 2989
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A +F +P ++ P RLYRTGD G++ + GR+D QVK+RG R+
Sbjct: 2990 WGYLSRPELTAEKFLPHPFSSAPG-ARLYRTGDRVRWRADGSLEFLGRSDFQVKVRGFRI 3048
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART-SAQHIEGKLRSALTH 434
+L E+E L Q PGV + VVL G+ ++ +V + G + A+ + + L
Sbjct: 3049 ELGEIESVLQQAPGVQEAVVLAREDSPGDKRLVAYVVGEDGVESVDARALRDHVLRKLPE 3108
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
Y++P + I +ES+PL NGKVDR+ L DA+ A + +
Sbjct: 3109 YLVPAIFIPMESLPLSANGKVDRKAL--------PAPDADRA--LTGASFEAPRDASEQA 3158
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
AVLG L + F+ELGG+S+ SI I KLR+RG + I + L T+ +
Sbjct: 3159 IADIWAAVLGLR---QLGIDDNFFELGGDSIRSIQVIAKLRERGLELPIMELLQHPTIRQ 3215
Query: 554 V 554
+
Sbjct: 3216 L 3216
Score = 192 bits (469), Expect = 2e-47
Identities = 168/560 (30%), Positives = 261/560 (46%), Gaps = 42/560 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++ +P RI+ +L++A +++ + P G+P ++ +
Sbjct: 571 VVGLLAILKAGGAYVPIDHHYPAERISLLLQEAGIGVLV---TTKPLA---EGLPASNSK 624
Query: 80 ELAQEATSHSADE-PMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + + P DA A + D +A V++TSGSTG PKGV + + A+ +RL
Sbjct: 625 HVCVDTDADVITALPHDAPLPATVGGDDLAYVMFTSGSTGRPKGVCIPHRAV-SRLVLA- 682
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
F + +E+ + + F S E+WG LLHG A L+L+ T +L + V
Sbjct: 683 NPFIHFGPDEVFLQLAPVAFDASTLELWGALLHG-ARLVLAPPHTPSLDELAALLTHHRV 741
Query: 199 PTL-LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL L + L + L ++ + G+ L + + G L N YG
Sbjct: 742 STLWLTAALFEQMVLHQGNALAGVRQVLAGGDVLPPLRVRQHLERIPL--GAVLVNGYGP 799
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + L + ++PIGRPL + Y+LD + P PGE++V G L
Sbjct: 800 TENTTFSATHSLRAGEAFGT--SVPIGRPLGHSTAYVLDSRMEPVPVGVPGELFVGGDGL 857
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A +F +P ++ P RLYRTGD G++ + GR+D QVK+RG R
Sbjct: 858 AWGYLSRPELTAEKFLPHPFSSAPG-ARLYRTGDRVRWRADGSLEFLGRSDFQVKVRGFR 916
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ------HIEGKL 428
++L E+E L Q PGV + VVL G+ ++ + AR+ Q I L
Sbjct: 917 IELGEIESVLQQAPGVQEAVVLAREDAPGDKRLVAYFVPTAAARSEEQAANAVGGIRTFL 976
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
++ L YM+P V + +E +PL NGKVDR+ L Y + N +
Sbjct: 977 KARLPEYMLPAVFMPLEVLPLSPNGKVDRKALPAPYADLNRTG----------TPFEAPR 1026
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
VLG G + F+ELGG+S+ SI I KLR++G + + L
Sbjct: 1027 NASEQTLADIWAEVLGLRQVG---IDDSFFELGGDSIRSIQVIAKLREQGLELPTLELLQ 1083
Query: 548 ASTLGE---VLSKMSTDPNG 564
T+ E V+ S P G
Sbjct: 1084 HPTIRELTGVIKATSVAPAG 1103
Score = 175 bits (425), Expect = 5e-42
Identities = 159/528 (30%), Positives = 246/528 (46%), Gaps = 48/528 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AYVPM+P++P R+ +++ D+ V+ + V +
Sbjct: 3771 VVGVLAILKAGGAYVPMDPAYPAQRLAYMVSDSNVGCVLTQQRVADKLAGHK-VEVLCVD 3829
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN-RLWWQF 138
+ A S P + +A V+YTSGSTG PKGV + ++++ N R
Sbjct: 3830 DAAPTNEPRSESNPPRLSE-----PEHLAYVIYTSGSTGKPKGVMVQHASVMNLRAALAA 3884
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NI 192
+ D +L+F SV + L G AL ++ + D + ++ ++
Sbjct: 3885 AAYAGMDKPLRVSLNASLSFDASVQHLV-QLADGHALCVVPQTAREDARIMLAWLEQNDV 3943
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+ L P+LLR +L+ L A RPLR L GE L + L + + +
Sbjct: 3944 DVLDCAPSLLR-LLLDEGLA-AHRPLRVL----AGGEALDEALWARLSAH----PRIECF 3993
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE D T + G+ L P++ G PL N Y+LD L P PGE+++
Sbjct: 3994 NVYGPTECTVDSTLRPVRGAS---LPPSL--GGPLANAQTYVLDAYLQPVPVGVPGELYI 4048
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
GA LA GY+ A+RF NP +T RLYRTGD L +G + + GR D QVK
Sbjct: 4049 GGAGLARGYLNRPELTADRFIPNPFSTASG-ARLYRTGDRARWLPQGELEFLGRIDFQVK 4107
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++L E+E AL Q P V VVL G ++ +V +P A + L+
Sbjct: 4108 LRGFRIELGEIESALRQHPAVRDTVVLVREDTPGLQRLVAYVVAEPAATVDSGTFRPFLK 4167
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
L +MMP + +E++PL +GKVDR+ L + E T+ + V
Sbjct: 4168 ERLPEHMMPSAFVTLEALPLNTSGKVDRRA-LPLPEETSPRHEVYVP----------PRD 4216
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR 536
+LG + +S +S F+ELGG+SL ++ ++ LR R
Sbjct: 4217 AYELELARLFEELLGVS---PISAKSDFFELGGHSLLAVRLLSMLRAR 4261
Score = 163 bits (396), Expect = 2e-38
Identities = 139/452 (30%), Positives = 215/452 (47%), Gaps = 34/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AYVPM+P++P R+ +++ D+ S ++ + V +
Sbjct: 1643 VVGVLAILKAGGAYVPMDPAYPAQRLAYMVSDSNVSCMLTQQRVADKIAGHK-VEVLCVD 1701
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ S A P +A V+YTSGSTG+PKGV + ++++ N
Sbjct: 1702 DAGLVNGSRDASNPPRLSR-----PQHLAYVIYTSGSTGMPKGVMVQHASVMNLRAALAA 1756
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
T + + V A D+ + L G AL ++S+ T D + ++ +++
Sbjct: 1757 TAYAGVGKPLRVSLNASLSFDASVQQLVQLADGHALCVVSQATREDTRLMLAWLERHSVD 1816
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L P+ LR +L+ L A PLR L GE L + L + + + N
Sbjct: 1817 VLDCAPSQLR-LLLDEGLA-AHSPLRVL----AGGEALDEALWARLSAH----PHIECFN 1866
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D T + G+ L P++ G PL N Y+LD L P PGE+++
Sbjct: 1867 VYGPTECTVDSTLRPVRGAS---LPPSL--GGPLANAQTYVLDAYLQPVPVGVPGELYIG 1921
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA LA GY+ A+RF NP +T RLYRTGD L +G + + GR D QVK+
Sbjct: 1922 GAGLARGYLNRPELTADRFIPNPFSTASG-ARLYRTGDRARWLPQGELEFLGRIDFQVKV 1980
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART--SAQHIEGKL 428
RG R++L E+E AL Q P V VVL G ++ +V + A T + L
Sbjct: 1981 RGFRIELGEIESALRQHPAVRDTVVLVREDTPGLQRLVAYVVAEAEATTVVDSGTFRPFL 2040
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ L +M+P + +E++PL NGK+DR+ L
Sbjct: 2041 KERLPEHMVPSAFVTLEALPLTPNGKLDRKAL 2072
>UniRef50_Q0X0B9 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Streptomyces lasaliensis|Rep: Putative
non-ribosomal peptide synthetase - Streptomyces
lasaliensis
Length = 2609
Score = 200 bits (489), Expect = 9e-50
Identities = 155/463 (33%), Positives = 237/463 (51%), Gaps = 47/463 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIY-DDSADPSMFKESGVPFASF 78
++AL+A +AGAAY+P++P +P R+ +L DA P+L++ D+AD + VP
Sbjct: 533 VVALIAVLRAGAAYLPVDPDYPAARVAFMLADARPALLLTAKDTAD--RLPPTDVPVLLV 590
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+++ A+ P+ A D A ++YTSGSTG PKGV ++++AI NRL W
Sbjct: 591 DDVPP------AEGPVAP---AAHGVDHPAYMIYTSGSTGRPKGVVVTHAAIVNRLLWMQ 641
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
F ++ + + KT+ +F SV E + PL+ G L+I + RDP L + R V
Sbjct: 642 DRFRLDGTDRV-LQKTSASFDVSVWEFFWPLITGATLVIARPDGHRDPDYLAELIRRAGV 700
Query: 199 PT--LLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
T + S+L A+ L+ VCSGE L ELA+ F + FG L N YG
Sbjct: 701 TTAHFVPSMLAEFVTDGAAAACTGLRRVVCSGEALPAELAARFHRTFG----VPLHNLYG 756
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DVT + + T+PIG P+ N A+Y+LD L P G++++AGA
Sbjct: 757 PTEAAVDVTAWEYRPGAR-----TVPIGTPIWNTALYVLDSRLRPLPPGVHGDLYIAGAG 811
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
LA GY G A RF P +P +R+YRTGD +G + +AGR D QVKIRG
Sbjct: 812 LARGYHDRPGLTAERFVACPFG-EPG-RRMYRTGDLARWNAQGELEFAGRADHQVKIRGF 869
Query: 374 RVDLLEVERALAQVPGVDKCVVLC---YGLDRGNPEILGFV--TTKPGARTSA------- 421
RV+ E+E L P V + V+ G D +++ ++ T G+R +
Sbjct: 870 RVEPQEIEDTLTGHPAVLRAAVVARPGRGADAA-AQLVAYIVPVTAGGSRPAGADWDLHA 928
Query: 422 ----QHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ G + + L +++P + ++ +P+ NGK+DR GL
Sbjct: 929 GVDLAELRGFVAARLPAHLVPAAFVALDRLPMTANGKLDRAGL 971
Score = 172 bits (419), Expect = 3e-41
Identities = 134/446 (30%), Positives = 213/446 (47%), Gaps = 38/446 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA WKAG YVP++P +P R+ +++D+ P LV+ D+ AS +
Sbjct: 2096 VVALLAVWKAGGTYVPVDPEYPAARVRAVVEDSAPVLVL-DEKR-----------LASVD 2143
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + H A P PL +D A V+YTSGSTG PKGV + + A+ L +
Sbjct: 2144 --LTDRSPHPARGPR-----VPLGADHAAYVIYTSGSTGTPKGVVVRHGALAILLTGMQK 2196
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + + + T + F + E++ PLL G +++ ++ P L+++ R V
Sbjct: 2197 RFALTPDDRLLACAT-VAFDIAALELFLPLLTGGRVVLAGKDDITQPTALLDLVRQSRVT 2255
Query: 200 TLLRSILMYLALGP-ASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + ++ +L A L L++ + +GE L LA ++ ++ N YG T
Sbjct: 2256 VMQATPALWQSLATHAPDCLMGLRV-ISTGEALPLALAETLSRHAA-----EVTNLYGPT 2309
Query: 259 EVMGDVTYY-VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
E T VL G + P++ G P+ I +LD L P G++W+AG L
Sbjct: 2310 ETTVYATAARVLPGGRGMP--PSV--GGPVAGTRILVLDRALRPVPPGATGDLWIAGDGL 2365
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY G A RF P P R+YR+GD G V Y GR+D Q+K+RGHR
Sbjct: 2366 ARGYHNRPGMTAERFVACPFG--PPGTRMYRSGDLARWTAAGEVEYLGRSDHQIKLRGHR 2423
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++ EVE L P V + V+ G+ ++ +V + GA + + + L
Sbjct: 2424 IEPAEVEHTLTCHPAVRRAAVIVREDRPGDRRLVAYVVPEAGAEPTTALLREVVGQRLPA 2483
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + + +PL NGK+DR L
Sbjct: 2484 YMIPAAFVTLTEVPLTPNGKLDRSAL 2509
>UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2;
Bacillus subtilis|Rep: Polyketide synthase of type I -
Bacillus subtilis
Length = 5488
Score = 200 bits (488), Expect = 1e-49
Identities = 143/457 (31%), Positives = 233/457 (50%), Gaps = 25/457 (5%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F I+ +L KAG AYVP++PSFPQ R+ ++LKD++ S+V+ + + SG+ +
Sbjct: 527 FDMIIGILGILKAGGAYVPLDPSFPQERLKYMLKDSQASIVLTQPNVHDRI---SGLTGS 583
Query: 77 SFEELAQE-ATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
+ + E A + + + + + +A ++YTSGSTG PKGV + + +I N L
Sbjct: 584 HVKAINIELACRNGYTDQQSSGLKREVKPEHLAYIIYTSGSTGEPKGVMVEHRSIMNTLN 643
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ------KL 189
+ +P + +E+ + KT F S+ E++G + L+IL + PQ +
Sbjct: 644 FLESHYPVT-AEDAYLLKTNYVFDVSISELFGWFIGDGRLVILPPNGEKSPQLCMDYIET 702
Query: 190 VNIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
+ + VP +L L LK + +GE K L + F N
Sbjct: 703 YKVTHINFVPAMLHVFLEMAKDNKRFTEDGPLKYMMVAGEAFPKVLVKKAVSLFTN---C 759
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
++ N YG TE Y+ G + + T PIG+P+ N IY++D+ L P +PGE
Sbjct: 760 RVENIYGPTEASIYAAYFGC-GKGDIASHHT-PIGKPVSNTKIYIVDQHLKPVPIGKPGE 817
Query: 310 VWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
+ +AGA LA GY G A +F DNP + +LY++GD L G + Y GR D+
Sbjct: 818 LCIAGAGLARGYFKKPGLTAEKFIDNPFESG---TKLYKSGDSARWLPDGNIEYLGRIDS 874
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIE 425
QVKIRG RV+L +E L + PG+ V+ L+ G+ ++ + T + G A + + +
Sbjct: 875 QVKIRGFRVELGAIETKLGEFPGILDQAVVVKQLE-GHQQLAAYYTEESGHASANPKDLR 933
Query: 426 GKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLK 461
L+S+L YM+P I ++ +PL +GKV+R+ L K
Sbjct: 934 LHLKSSLPEYMIPSHFIRLDELPLSPSGKVNRKELEK 970
>UniRef50_A4BRH4 Cluster: Probable peptide synthetase protein; n=3;
Bacteria|Rep: Probable peptide synthetase protein -
Nitrococcus mobilis Nb-231
Length = 2660
Score = 200 bits (488), Expect = 1e-49
Identities = 151/453 (33%), Positives = 225/453 (49%), Gaps = 33/453 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AY+P++P+ P+ R ++L+ A LV+ ++ P++ G +
Sbjct: 1627 LVALLAIHKAGGAYLPIDPALPRARNAYVLEHAAAVLVLTREALRPAL---QGAERVTAL 1683
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW-WQF 138
E + + +D +D P+ +A VLYTSGSTG PKGV++ A N L Q
Sbjct: 1684 EGLDKTLAELSDRDLDL----PVHPRQLAYVLYTSGSTGRPKGVQVEREAFVNFLHAMQD 1739
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-ERLVL 197
R SD + V T L+F + E++ PL+ G +++ RE +P L+ + +R +
Sbjct: 1740 RIRLGSDDRLLAV--TTLSFDIAGLELFLPLVQGACVVVARREQALEPAALLGLMQRHGI 1797
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + + L++ +C GE L ELA G +L N YG
Sbjct: 1798 TLMQATPATWQMLVEHEAAAWAGLRV-LCGGEALRGELAGRLLAR-----GVRLLNVYGP 1851
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T + +E D IPIGRP+ N +Y+LD L P GE+++ GA L
Sbjct: 1852 TETTVWSTAWPVECVDAA----VIPIGRPIANTRLYVLDARLEPVPPGVVGELYIGGAGL 1907
Query: 318 AAGYVGGG--GANRFCDNPH-----ATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
A GY G A F NP A RLYRTGD G + Y GR D QVK
Sbjct: 1908 ARGYAQGPALSAAAFVPNPFPKAGLAGAGPGSRLYRTGDLARWRADGVLEYVGRIDHQVK 1967
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFV--TTKPGARTSAQHIEGK 427
+RG RV+L E+E AL +P V + VV G ++G+V T PG + ++ +
Sbjct: 1968 LRGFRVELAEIEVALESLPAVREAVVTAREAPSGK-RLVGYVVPTVAPGRAGLTEELQAQ 2026
Query: 428 LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L+ AL YM+P Q++ +E +PL NGK+DR+ L
Sbjct: 2027 LKEALPEYMVPAQLVVLEKLPLTPNGKLDRKAL 2059
Score = 173 bits (422), Expect = 1e-41
Identities = 138/451 (30%), Positives = 220/451 (48%), Gaps = 28/451 (6%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE-- 80
++ +KAG Y+P++P P R+ +L D + V+ ++ +++ +
Sbjct: 559 IIGVFKAGGGYLPLDPRQPVRRLAQML-DLSRARVVVSTECLRAVLEQALAELPAERRPI 617
Query: 81 -LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L EA S D P+ + +A V+YTSGSTG+PKGV + + + N Q
Sbjct: 618 WLTLEALS-GQDWPVHDPGVRT-GPHHLAYVIYTSGSTGVPKGVMVEQAGMLNN---QLS 672
Query: 140 TFPYSDSEE--ICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
PY E + A F SV + LL G + I+ DP L+
Sbjct: 673 KVPYLGLTEGDVIAQTAAAGFDISVWQFLTGLLCGARVEIVPDAIAHDPMALLKHVNATG 732
Query: 198 VPTLLRSI--LMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ T+L S+ L+ L + L+ L+ + +GE L+ ELA ++F+ + + L N Y
Sbjct: 733 I-TVLESVPSLIQGMLAEEAVELKGLRWLLPTGEALAPELARQWFRRYPH---IPLVNAY 788
Query: 256 GSTEVMGDVTYYVL-EGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
G E DV + L EG ++ +PIGRP DN +Y+LD +L P GE+ +AG
Sbjct: 789 GPAECSDDVALHTLREGPASGTVH--LPIGRPTDNTRLYVLDGQLQPVPVGVTGELCIAG 846
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
A + GY+ A F +P+A P +RLYR+GD G + Y GR+D QVK+R
Sbjct: 847 AGVGRGYLHDPARTAQAFVPHPYAQTPG-ERLYRSGDLARWRADGVLEYVGRSDHQVKVR 905
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFV--TTKPGARTSAQHIEGKLR 429
G R++L E+E L + GV + VV+ G ++G+V T ++ L+
Sbjct: 906 GFRIELGEIEARLLEHQGVREAVVVVREAPSGK-HLVGYVVPTALEAGAELGDALKAHLK 964
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
A+ YM+P Q++ +E +PL NGK+DR+ L
Sbjct: 965 EAIPEYMVPGQIVVLEQLPLTPNGKLDRKAL 995
>UniRef50_A0YGI5 Cluster: Peptide synthetase; n=1; marine gamma
proteobacterium HTCC2143|Rep: Peptide synthetase - marine
gamma proteobacterium HTCC2143
Length = 1499
Score = 200 bits (488), Expect = 1e-49
Identities = 159/521 (30%), Positives = 242/521 (46%), Gaps = 39/521 (7%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
S ++ LA K GA Y+P++P FP R+ ++L D+ + V+ DDS P +E+ + +
Sbjct: 525 SLLIGTLAIQKLGAIYLPLDPDFPTDRLLYMLDDSGATAVLEDDST-PQAVREAEIKHLN 583
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+L D +D L + + A +YTSGSTG PKGVR+ A+ N L
Sbjct: 584 MGDLVLAGVR---DVSID---LPDPSLERAAYTIYTSGSTGKPKGVRIQNGALINFLE-S 636
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERL 195
P + + T L+F SV E++ PL+ G LI SR+ +D ++L + E
Sbjct: 637 MADRPGCTESDTLLAVTTLSFDISVLELFLPLVTGATTLIASRDDVKDGERLAVLLKEGQ 696
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLW-VCSGETLSKELASEFFKYFGNEDGYKLANF 254
V + S L + R +L +C GE L ++LA E +L N
Sbjct: 697 VTIMQATPSTWRMLLTSEWGKDKSRRQLKALCGGEPLPQDLALELVSCVS-----ELWNM 751
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
+G TE T ++ SD L I IGRP+ N +Y+LD+ L+P S PGE+ + G
Sbjct: 752 FGPTETTVWSTCKKIQESDAL-----ITIGRPIANTQVYVLDDNLNPLPVSVPGELCIGG 806
Query: 315 ANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIRGH 373
A ++ GY N D+ T P R+YRTGD L G + + GR D QVK+RG+
Sbjct: 807 AGVSLGYHQRPALN---DDRFVTHPVLGRIYRTGDLAKALPNGEIQHLGRLDDQVKLRGY 863
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E AL V++ VV L + ++ I KLR L
Sbjct: 864 RIELGEIEMALKSCVEVEQAVVYLLNLGEQDVRVVACCVPVADRALETISIRKKLRECLP 923
Query: 434 HYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+PQ + + IPL NGKVDR+ L + + ++ A+V
Sbjct: 924 SYMVPQYFLSISKIPLTPNGKVDRRSLPRPEMSASSILGAKV-----LQTDSEKLIASVW 978
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL 533
+G +GR F+ELGG+SL ++ I ++
Sbjct: 979 SDLLKIGGAIGR--------EDNFFELGGHSLLALQAIRQI 1011
>UniRef50_Q9RK14 Cluster: Putative peptide synthetase; n=1;
Streptomyces coelicolor|Rep: Putative peptide synthetase
- Streptomyces coelicolor
Length = 3643
Score = 200 bits (487), Expect = 2e-49
Identities = 167/559 (29%), Positives = 260/559 (46%), Gaps = 43/559 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA +AG A+VP++P +P R +++DA +V D S +P+ G P A
Sbjct: 201 VIGLLAVLRAGGAFVPLDPHWPAERRAVVIEDAGV-VVQLDASGEPA----PGEPEAVAV 255
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L D P + +T + D++A V++TSGSTG PKG + + AI RL WQ
Sbjct: 256 DLGDW---RFGDRPTE-DTGVTVPGDALAYVIFTSGSTGRPKGAMIRHEAISERLLWQIH 311
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
++ ++K L+F S+ EI+ PL+ G L++L RDP L+++ E+ V
Sbjct: 312 EILGFGHDDASLFKAPLSFDISINEIFLPLVSGGRLVVLRPGGERDPHHLLSVIDEQRVT 371
Query: 198 VPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L+ S+L + L + S L L+ C GE L+ EL ++ F L + YG
Sbjct: 372 FTYLVSSMLDVLLEMAGDSGRLDSLRHVWCGGEVLTPEL----YERFRTRLDIPLYHGYG 427
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E V++ V G+ + + IGR N +Y+LD+EL P GE++ G
Sbjct: 428 PAETTIGVSHVVYRGAAE---RLSTSIGRANPNTRLYVLDDELRPVPVGVGGELYAGGLL 484
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGH 373
L GYV G A+RF NP A + RLYRTGD G++ + GR D QVKIRG
Sbjct: 485 LGRGYVNAPGLTASRFVANPFA--DDGSRLYRTGDLARFAPDGSLDFLGRADNQVKIRGM 542
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR-TSAQHIEGKLRSAL 432
R+++ +VE LA+ P V V+ G ++G+V G A ++ +
Sbjct: 543 RLEIEDVEVGLAEHPRVRHTCVVARKNTAGGTYLVGYVIPAAGHEDLRADEVKAWAGEHM 602
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P V+ + PL NGK+DR L E + S
Sbjct: 603 VEYMVPTHVVVMTEFPLTANGKLDRNAL------------PEPVIPAGSS-----APPTT 645
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
AV + + F++LGG+S+ +I + +LRD G YV ST+
Sbjct: 646 DEERTVCAAVAALLQLDRVGVDQDFFQLGGDSILAISLLGRLRDAGLYVTARQIFTHSTV 705
Query: 552 GEVLSKMSTDPNGGADSKE 570
G + + S + D ++
Sbjct: 706 GALAAVASREDTTVVDHRD 724
Score = 171 bits (415), Expect = 8e-41
Identities = 147/467 (31%), Positives = 224/467 (47%), Gaps = 35/467 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLV-IYDDSAD--PSMFKESGVPFA 76
++AL+A AG AYVP++ ++P R+ ++L D+ P +V + + D + + VP A
Sbjct: 1689 VVALVAVVGAGGAYVPLDLAYPDERLEYVLADSAPQVVLVTPEQRDRFARLLDRANVP-A 1747
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
L +E +A+ A P A V+YTSGSTG PKGV + +S++ L
Sbjct: 1748 RLLVLGEEPPPTAAEPGPAARWHDP------AYVIYTSGSTGRPKGVVVPHSSVVT-LLA 1800
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIE 193
R +++ V + +F +V E+WG L HG LL+ TR P +LV E
Sbjct: 1801 NTRPVMNFGPDDVWVQFHSFSFDFAVWELWGALTHGGELLVPDYGLTRSPVDFHRLVR-E 1859
Query: 194 RLVLVPTLLRSILMYLALGP--ASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
R V V S A A PL L+ + GE L ++ G E +L
Sbjct: 1860 RGVTVLNQTPSAFHRFAEADRHAGEPLPALRRIIFGGEGLDLARLRDWVARHGTESP-EL 1918
Query: 252 ANFYGSTEVMGDVTYYVLEGSD-QLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
N YG TE VT+ VL +D PIG P+ +LLD+ L P G +
Sbjct: 1919 VNMYGITETTVHVTHRVLTAADFAPGDRAASPIGGPVPGLVTHLLDDRLRPVPPGRVGAI 1978
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQ 367
+VAG ++ GY+G G A RF NP + R+Y TGD + G + +AGR D Q
Sbjct: 1979 YVAGDQVSLGYLGRPGLTAGRFVANPFTA--DGSRMYHTGDLARRTLDGQLEFAGRADDQ 2036
Query: 368 VKIRGHRVDLLEVERALAQVPG-VDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
V+++G R++ EVE A+ + G VD V + D ++G V + G
Sbjct: 2037 VQLKGFRIEPGEVESAIRDLDGVVDAAVTVADTDDHLVAHVVGRVPA---------DLTG 2087
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDA 472
L + L +M+P +V+ V+++PL VNGK+DR+ L + T + + A
Sbjct: 2088 LLSAKLPAHMVPGRVLPVDALPLTVNGKLDRRALAERATRTPSAEPA 2134
Score = 149 bits (361), Expect = 3e-34
Identities = 145/457 (31%), Positives = 200/457 (43%), Gaps = 40/457 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+I+AL A + GAAYVP+E P RI ++ DA P V+ + P + G
Sbjct: 3118 SIVALFAVLRTGAAYVPLELDHPDERIAAVVADARPDAVLTVSAVTPRL--TGGPDLIEL 3175
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ +A P D + L A +YTSGSTG PKGV Y+ + N L
Sbjct: 3176 DRPLPDAEPCVTFAPDDPDRLR-----HPAYTIYTSGSTGRPKGVVTEYAGLTNMLVNHR 3230
Query: 139 RTF--PYSDSEEICVWKTALTFVDSVCEIWGPLL---HGRALLILSRETTRDPQKLV--- 190
R P ++ A T + W LL G + + E RD +LV
Sbjct: 3231 RRIFEPVLARHGHRTFRVAHTVSFAFDMSWEELLWLADGHEVHVCDEELRRDAPRLVAYC 3290
Query: 191 ---NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
I+ + + PT + +L A G P RR L + GE ++ L + G
Sbjct: 3291 LEHGIDVVNVTPTYAQQLL---AEGLLDDPARRPALVLLGGEAVTPALWTRLAATEGTV- 3346
Query: 248 GYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP 307
GY N YG TE T L G + P +G +DN +Y+LD L P D P
Sbjct: 3347 GY---NLYGPTEY----TINTL-GVGTFEC-PDPVVGVAIDNTDVYVLDPWLRPLPDGVP 3397
Query: 308 GEVWVAGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRT 364
GE++VAG +A GY+G A+RF P E R+YRTGD G ++Y GRT
Sbjct: 3398 GELYVAGVGIARGYLGQPAQTAHRFVACPFGAPGE--RMYRTGDLVVRRPDGNLMYLGRT 3455
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDR-GNPEILGFVTTKPGARTSAQH 423
D QVKIRGHRV+ EVE A A P V + + L GA
Sbjct: 3456 DQQVKIRGHRVEPGEVEAAFAAHPAVRFVAAVAQPDPQVDGAHRLAAYLVLDGA--DLAE 3513
Query: 424 IEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ ++ +AL ++ P +V+ IPL VNGK D + L
Sbjct: 3514 VAAQVGAALPDFLRPTHYAQVDRIPLTVNGKADTKAL 3550
>UniRef50_Q8YWG6 Cluster: Peptide synthetase; n=3; Nostocaceae|Rep:
Peptide synthetase - Anabaena sp. (strain PCC 7120)
Length = 987
Score = 200 bits (487), Expect = 2e-49
Identities = 146/465 (31%), Positives = 217/465 (46%), Gaps = 34/465 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDA-----------EPSLVIYDDSADP--- 65
++ +L KAG +Y+P++P +P R+ +IL+ A LV A P
Sbjct: 70 MIGILGILKAGGSYIPLDPGYPTDRLRYILEHATIQTLLTEHQVSQQLVACVQEALPLQT 129
Query: 66 SMFKESGVPFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRL 125
MF + G P + L Q DA L + D + ++LYTSGSTG PKGV L
Sbjct: 130 VMFLDEGEPLGEIQSLTQITAETWQSLSDDALELCN-SPDDLMVILYTSGSTGRPKGVML 188
Query: 126 SYSAICNRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRD 185
++ NRL W TF + + +T+ F SV EI+ L+ G + + RE +
Sbjct: 189 NHRGYMNRLTWMQNTFSLQPGDRV-AQRTSFCFDISVWEIFWTLMSGATICPVQREVVLN 247
Query: 186 PQKL------VNIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEF 239
P + I + VP+L + L S P +L+ + SGE L +
Sbjct: 248 PWEFARWIQETQINVMHFVPSLFGEFISALENETWSFP--QLRWLMFSGEALPMSFIQRW 305
Query: 240 FKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEEL 299
G + G LAN YG TE DVT +++ L IPIG+ +DN + +LD +
Sbjct: 306 IDRHGLKTG--LANLYGPTEASIDVTCHLITERPDERLTTQIPIGKAIDNVYVKVLDGGM 363
Query: 300 SPTRDSEPGEVWVAGANLAAGYVGG--GGANRFCDNPHATQPEFQRLYRTGDF-GTLVKG 356
P + GE+W+ G LA GY+ A FC NP P +YRTGD L G
Sbjct: 364 QPVQPGNMGELWLGGVQLALGYLKDPEKTAQAFCPNPFTDIPG-DYIYRTGDLVKELPDG 422
Query: 357 AVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG 416
+ Y GR D QVKIRG R++L E+E L P V + L G ++ ++ G
Sbjct: 423 TIEYHGRIDHQVKIRGFRIELGEIESVLTTHPDVREAAALAVDYGEGQKRLVACIS---G 479
Query: 417 ARTSAQHIEGKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLL 460
+ + ++ L L HYM+PQ + ++S+P NGK+DR+ L+
Sbjct: 480 NKIKNRFLKEYLEQKLPHYMIPQRFLWLDSLPKNHNGKLDRKALV 524
>UniRef50_A4PHM3 Cluster: Hybrid non ribosomal peptide
synthetase-polyketide synthase; n=2; cellular
organisms|Rep: Hybrid non ribosomal peptide
synthetase-polyketide synthase - Streptomyces virginiae
Length = 2589
Score = 200 bits (487), Expect = 2e-49
Identities = 144/456 (31%), Positives = 215/456 (47%), Gaps = 21/456 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL+ +AGA YVP++P+ P R+ ++L+D+ +V+ D + V
Sbjct: 973 VVALVGIVRAGAVYVPVDPANPPERVRYLLEDSGARVVVADAALAAVPAAAGAVVLCQDR 1032
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + P E + P D +YTSG+TG PKG R ++ NR+ W
Sbjct: 1033 DEDRALLASRPVTPPQVE-VGP---DDPVYTIYTSGTTGKPKGCRNTHRGFVNRVRWMQD 1088
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
FP + + KT F S E + PLL G ++++ DP L + E V
Sbjct: 1089 RFPLGADDRVAQ-KTPYGFDVSAWEFFWPLLAGASIVVARPGGHVDPGYLARLLREERVT 1147
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + S+L A+ L+ SGE L FF+ DG +L N YG
Sbjct: 1148 VAHFVPSVLGLFLRDRAASDCASLRYVFASGEALPVATMKRFFQVL--PDGAELHNLYGP 1205
Query: 258 TEVMGDVTYYVLEGS-DQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DVT++ D+ PT+PIGRP+ I+++DE ++ D PGE+ + GA
Sbjct: 1206 TEAAIDVTHWACRPDWDE----PTVPIGRPIARTRIHVVDERMARVPDGTPGEIVIGGAG 1261
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
+A GY G A RF +P A P RLYRTGD G L G + Y GR D Q K+RG
Sbjct: 1262 VALGYHGRPELTAERFVASPFADDPS-PRLYRTGDLGQLGPDGEIRYLGRIDGQFKLRGL 1320
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA--RTSAQHIEGKLRSA 431
R++ EVE AL ++PGV + VL +IL V + S + L +
Sbjct: 1321 RIEPEEVEAALTELPGVSEARVLPVTDPATGEQILAAVCVEADGTLAPSVGQMRRDLARS 1380
Query: 432 LTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENT 466
L Y++P V+ +PL NGK+DR+ ++ T
Sbjct: 1381 LPSYLVPSSFRFVDRLPLTANGKLDRRAATALFGTT 1416
>UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1;
Clostridium thermocellum ATCC 27405|Rep: Amino acid
adenylation domain - Clostridium thermocellum (strain
ATCC 27405 / DSM 1237)
Length = 625
Score = 200 bits (487), Expect = 2e-49
Identities = 138/446 (30%), Positives = 235/446 (52%), Gaps = 27/446 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+L KAG AY+P+EP++P+ R+ +++ D++ ++I S+ + +S V + +
Sbjct: 88 IIAILGVLKAGGAYIPLEPAYPKERLNYMINDSKMPVLI-TKSSFLDIVPDSNVTVVNMD 146
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L E S + E D + D++ ++YTSGSTG PKGV +S+ A+ N + +
Sbjct: 147 -LDWERISKESKENPDCN----INYDNLVYIIYTSGSTGTPKGVEISHGALVNLIHSMLK 201
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
P E+ + +AL+F SV +I+ PL G +++++ ++ KL+ E +
Sbjct: 202 E-PGMTCEDRLLSVSALSFDMSVFDIFVPLSAGASIIMVGDCIAKNGTKLIQALEENSIT 260
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V S L L + ++LK+ +C GE L +EL ++ NE G + N YG
Sbjct: 261 VMQATPSTWRML-LESGWKGNKQLKI-LCGGEALPRELVNQL-----NEKGAVVWNMYGL 313
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE+ Y V+ D +PIG P+DN Y+LDE+L P E GE+++ G +
Sbjct: 314 TEL---TVYSVISKVTSGD--GPVPIGYPIDNTQAYILDEDLKPVPFGEVGELYIGGDGV 368
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
GY G + ++ NP + + R+ +TGD L G++ Y GR D Q+K+RG R
Sbjct: 369 GRGYFGKPELTSEKYIQNPFSDN-QSDRICKTGDLARFLPDGSIEYLGRADFQIKLRGFR 427
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E A+ + P V + VV+ G+ I+ + TK S++ + L++ L
Sbjct: 428 IELGEIESAIEKHPWVQQAVVV-KDNGEGDQHIVAYFRTKSEQVPSSEDMRSFLKNTLPD 486
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM+P ++++ PL NGKVDR+ L
Sbjct: 487 YMIPSFFVQIDEFPLTPNGKVDRKSL 512
>UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D; n=4;
Bacteria|Rep: Linear gramicidin synthetase subunit D -
Mycobacterium avium (strain 104)
Length = 10421
Score = 200 bits (487), Expect = 2e-49
Identities = 178/568 (31%), Positives = 263/568 (46%), Gaps = 59/568 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+L K+GAAY+P++P+ P RI +L DA P + I P + + VP
Sbjct: 5595 IVAILGVLKSGAAYLPIDPALPGERIGFMLADAAPLVAISTAELAPRLHGQHDVPVVDVH 5654
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A EA SA L P +D IA ++YTSG+TG+PKGV +S+ + L +
Sbjct: 5655 DPAIEAAPSSA--------LPPPGADDIAYLIYTSGTTGVPKGVAVSHRNVAQLLTAE-- 5704
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
S VW +L F SV EI+G LHG L+++ R P+ L +
Sbjct: 5705 ----SGLPREGVWSQWHSLAFDVSVWEIFGAQLHGGRLVVIPESVARSPEDLHALLITEQ 5760
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V L ++ AL P L L L V +GE EL + G + N YG
Sbjct: 5761 VSVLSQTPSAAGALSPEG--LEDLTL-VVAGEACPSELVDRW------APGRTMINAYGP 5811
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE Y + + +PIG P+ A+++LDE L P GE++VAGA +
Sbjct: 5812 TEA---TVYAAISAPLRPGALGGVPIGSPVPGGAVFVLDEWLRPVPPGVVGELYVAGAGV 5868
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHR 374
A GY GG A+RF P R+YRTGD G + Y GR D QVKIRG+R
Sbjct: 5869 ACGYWRRGGLTASRFVACPFGAPG--ARMYRTGDLVRWRGDGQLDYLGRVDEQVKIRGYR 5926
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L EV ALA V GVD+ VV+ + ++G++T G A + L L
Sbjct: 5927 IELGEVRAALAWVDGVDQAVVVAREDRPRDKRLVGYIT---GTADPAA-VRAALAERLPA 5982
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL-LKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P V+ +++IPL NGK+D + L Y + + + AV+
Sbjct: 5983 YMVPAAVVTLDAIPLTPNGKLDTRALPAPEYSDADRYRAPDNAVE--------------E 6028
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLG 552
VLG G + F++LGG+S++S+ +T+ R G + D T+
Sbjct: 6029 ILAGIYAQVLGVQRVG---VDDSFFDLGGDSISSMQVVTRARAAGLVCKTRDIFVEQTVA 6085
Query: 553 EVLSKMS--TDPNGGADSKEATFTAVPM 578
L++++ D + AD TA P+
Sbjct: 6086 R-LARVAEVADADAAADEGVGEITATPI 6112
Score = 187 bits (456), Expect = 9e-46
Identities = 170/568 (29%), Positives = 255/568 (44%), Gaps = 59/568 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA KAGAAY+P++P+ P RI +L DA P + I P + V
Sbjct: 8140 IVAILAVLKAGAAYLPIDPALPDERIGFMLADAAPMVAISTAELAPRLHGHHVVVL---- 8195
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ A P L P +D IA ++YTSG+TG+PKGV +S+ + L
Sbjct: 8196 DVHDPAVDTQPSTP-----LPPPGADDIAYLIYTSGTTGVPKGVAVSHRNVTQLLTAD-- 8248
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
S VW +L F SV EI+G LLHG L+++ R P +
Sbjct: 8249 ----SGLPREGVWSQWHSLAFDVSVWEIFGALLHGGRLVVIPDSVVRSPDDFHALLVDEQ 8304
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V L ++ L P L V +GE EL + G + N YG
Sbjct: 8305 VSVLSQTPSAAGTLSPEGLESTAL---VVAGEACPAELVDRW------APGRTMINAYGP 8355
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE Y + Q +PIG P+ +++LDE L P GE++VAGA +
Sbjct: 8356 TEA---TVYTAISAPLQPGSPAGVPIGFPVPGTGLFVLDESLRPVPPGVVGELYVAGAGV 8412
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGHR 374
A GY GG A+RF P +P R+YRTGD G + Y GR D QVK+RG+R
Sbjct: 8413 ACGYWRRGGLTASRFVACPFG-RPG-ARMYRTGDLVRWRGDGQLDYLGRADEQVKVRGYR 8470
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L EV ALA + GVD+ V+ G+ ++G++T G A+ +L L
Sbjct: 8471 IELGEVRSALAALDGVDQAAVVAREDRPGDKRLVGYIT---GDADPAE-ARARLGERLPA 8526
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL-LKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P ++ +++IPL NGK+D + L Y + E V+
Sbjct: 8527 YMVPAAIVALDAIPLTPNGKLDTRALPAPEYSDAGQYRAPETPVE--------------Q 8572
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLG 552
VLG G + F++LGG+S++S+ +T+ + G V D T+
Sbjct: 8573 TLAAIYAQVLGVQRVG---VDDSFFDLGGDSISSMQVVTRAKAAGLAVRTRDIFTEQTVA 8629
Query: 553 EV--LSKMSTDPNGGADSKEATFTAVPM 578
+ ++ ++ + G AD TA P+
Sbjct: 8630 RLARVAGVADEDGGPADEGTGEVTATPI 8657
Score = 174 bits (424), Expect = 7e-42
Identities = 151/451 (33%), Positives = 227/451 (50%), Gaps = 49/451 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+LA K GAAY+P++PS PQ R+ +L DAEP + +A+ + + +G P
Sbjct: 4542 VAAILAVLKTGAAYLPIDPSAPQTRVEFMLGDAEPIAAV--TTAELAQ-RLAGRP----- 4593
Query: 80 ELAQEATSHSADEP-MDA--ETLAPLTS-DSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
T D+P +D +T PL D IA ++YTSG+TG PKGV +++ + L
Sbjct: 4594 -----VTVVDVDDPGIDTLPDTALPLPDPDGIAYLIYTSGTTGAPKGVAVTHHNVTQLLG 4648
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IE 193
P C +L F SV EI+G LL G ++++ R P L + I
Sbjct: 4649 SLDAGLPSPGVWSQC---HSLAFDVSVWEIFGALLRGGRVVVMPEAVARSPHDLHDALIA 4705
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
R V V T S L L+ + L + L V +GE E+ ++ G + N
Sbjct: 4706 RHVTVLTQTPSALAMLS----PQGLESVSL-VLAGEACPPEVVDQW------APGRVMVN 4754
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIP-IGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE T + S L IP IG P+D A+++LDE L P GE++V
Sbjct: 4755 GYGPTE-----TSMCVSISAPLTAGSGIPPIGSPVDGAALFVLDESLRPVPPGVVGELYV 4809
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
AG+ +AAGY+G A RF P R+YRTGD G + Y GR D QVK
Sbjct: 4810 AGSGVAAGYLGRPSLTAARFVACPFGAPSA--RMYRTGDLVRWRADGQLDYLGRADEQVK 4867
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG+R++L E++ AL+ + GV++ VV+ + G+ ++G++T G A+ +L
Sbjct: 4868 VRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYIT---GTADPAE-ARARLG 4923
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P V+ +++IPL NGK+D + L
Sbjct: 4924 ERLPAYMVPAAVLGLDAIPLTPNGKLDARAL 4954
Score = 169 bits (411), Expect = 2e-40
Identities = 163/562 (29%), Positives = 252/562 (44%), Gaps = 53/562 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ++LA K GAAY+P++P+ P+ RI +L DA+P + S + +G A
Sbjct: 524 VASILAVLKTGAAYLPIDPAAPETRIGFMLADAKPVAAL-------STAELAGRLEAHGM 576
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ D P A +A +D +A V+YTSG+TG+PKGV +++ + L
Sbjct: 577 TVIDVNDPRIQDRPATALPVA--AADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLDA 634
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P + C + F SV EI+G LL G L+++ TR P++L ++ V
Sbjct: 635 GLPSAGVWSQC---HSYAFDVSVWEIFGALLRGGRLVVVPEAVTRAPEELHDVLVNEQVS 691
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L ++ L P L + L V GE E+ + G + N YG TE
Sbjct: 692 VLTQTPSAVAMLSPQG--LESVSL-VVVGEACPAEVVDRW------SGGRVMVNAYGPTE 742
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
T V + + PIG P+D +++LD L P GE++V GA +AA
Sbjct: 743 T----TMCVAISAPLAPGMGSPPIGVPVDGAGLFVLDAWLRPVPPGVVGELYVGGAGVAA 798
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRVD 376
GYVG G A+RF P R+YRTGD G + Y GR D QVK+RG+R++
Sbjct: 799 GYVGRSGLTASRFVACPFGAPGA--RMYRTGDLVCWRPDGQLDYRGRADEQVKVRGYRIE 856
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EV+ ALA + V++ VV+ G ++G++T G A+ L L YM
Sbjct: 857 LGEVQAALAGLDDVEQAVVIAREDRPGGKRLVGYIT---GTADPAE-ARTALAQRLPVYM 912
Query: 437 MP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXX 495
+P V+ +++IPL NGK+D + L +T E +
Sbjct: 913 VPAAVVALDAIPLTPNGKLDTRALPTPEYSTGEYRAPESPTE--------------EILA 958
Query: 496 XTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEVL 555
VLG G + F+ELGG+S+ S+ + + R G D T+ L
Sbjct: 959 GIYAEVLGVDRVG---VDESFFELGGDSILSLQVVARARAAGLTCRPRDVFVEQTVAR-L 1014
Query: 556 SKMSTDPNGGADSKEATFTAVP 577
+++ +G A+ + VP
Sbjct: 1015 ARVVGSGDGAAEVADEGVGPVP 1036
Score = 165 bits (400), Expect = 5e-39
Identities = 135/447 (30%), Positives = 210/447 (46%), Gaps = 39/447 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA K GAAY+P++P+ P RI +L D P+ + +A + +
Sbjct: 7084 IVAILAVLKTGAAYLPIDPALPAARIEFMLDDTAPTAAV-TTAALAGPLRGRDLTVVDIG 7142
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A H+A D D +A ++YTSG+TG+PKGV +S+ + RL+
Sbjct: 7143 DRALSRQPHTALPAPDP--------DHVAHIIYTSGTTGVPKGVAVSHHNV-TRLFDAQA 7193
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK---LVNIERLV 196
++++ + F SV EIWG LLHG L+++S R P L+ E +
Sbjct: 7194 VGVELSADQVWTQFHSYAFDYSVWEIWGALLHGGRLVVVSDAVARSPMDFHALLVAENVT 7253
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
++ ++ M G S L V E EL + G + N YG
Sbjct: 7254 VLSQTPSAVRMLSPQGLESAAL------VIGAEPCPPELLDRW------APGRTMVNVYG 7301
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T + + PIG P+ A+ +LD L P GE++VAG
Sbjct: 7302 PTEA----TIFSTASTPLAAGSGAPPIGSPVPGTALLVLDGWLRPVPAGVVGELYVAGRG 7357
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
+ GY+ G A+RF P R+YRTGD G + Y GR D QVKIRG+
Sbjct: 7358 VGYGYLRRAGLTASRFVACPFGAPGA--RMYRTGDLVRWRADGQLDYLGRADEQVKIRGY 7415
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R+++ E+ ALA + GVD+ VV+ G+ ++G++T G A+ +L L
Sbjct: 7416 RIEVGEIRSALAALDGVDEAVVIAREDRPGDKRLVGYIT---GDADPAE-ARARLAERLP 7471
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P V+ ++++P+ VNGK+D + L
Sbjct: 7472 AYMVPVAVVVLDALPMTVNGKLDLRAL 7498
Score = 162 bits (393), Expect = 4e-38
Identities = 134/451 (29%), Positives = 217/451 (48%), Gaps = 47/451 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM--FKESGVPFAS 77
I+A+LA K+GAAY+P++P+ P R+ +L DA P + + + + F + + A
Sbjct: 3487 IVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIVAVTTAALAERLHGFDLTVIDVAD 3546
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
Q AT+ +P D +A ++YTSG+TG+PKGV ++ + +L+
Sbjct: 3547 PAVATQPATAPPVPDP-----------DDVAHIIYTSGTTGVPKGVAVTQYNVA-QLFDD 3594
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
R ++ + F SV EIWG LLHG L+++ +R P + ++
Sbjct: 3595 LRIGIELSPRQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPETVSRSPNEFHDL----- 3649
Query: 198 VPTLLRSILMYLALGPASRPLRRLK-----LWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L+R + L P++ L R V E EL + G +
Sbjct: 3650 ---LVREHVTVLTQTPSAVGLLRTDGLDGTALVIGAEPCPPELVDRW------APGRTMV 3700
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE T + + + PIG P+ A ++LD+ L P GE+++
Sbjct: 3701 NVYGPTET----TMWACKSAPLTAGSGFPPIGAPVTRAAFFVLDDWLRPVPPGVVGELYL 3756
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
AG + GY G A RF P +P R+YRTGD G + Y GR D QVK
Sbjct: 3757 AGDGVGVGYWRRPGLTAARFLACPFG-EPG-TRMYRTGDLVRWRADGQLDYLGRADEQVK 3814
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG+R++L E++ AL+ + GV++ VV+ + G+ ++G+VT G+ A+ L
Sbjct: 3815 VRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYVT---GSVAPAK-ARAALA 3870
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P V+ ++S+P+ VNGK+D + L
Sbjct: 3871 ERLPAYMVPAAVVVLDSLPMTVNGKLDTRAL 3901
Score = 160 bits (388), Expect = 2e-37
Identities = 164/557 (29%), Positives = 247/557 (44%), Gaps = 55/557 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA K GAAY+P++ + P R+ +L D+ + + G A+ +
Sbjct: 9634 IVAILAVLKTGAAYLPIDAAAPAARVRFMLADSAAVAAVTTAGLRSRL---DGCDVAAID 9690
Query: 80 -ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E + T S P AP D IA V+YTSG+TG+PKGV +++ + L
Sbjct: 9691 IEDPRIQTRPSTPLP------APAPHD-IAYVIYTSGTTGVPKGVAVTHRNVTQLLEPLD 9743
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
P S + + F SV EI+G LL G L+++ TR P+ + V
Sbjct: 9744 AGLP---SPGVWTQSHSYAFDVSVWEIFGALLRGGRLVVVPEAVTRSPKDFHALLVDEEV 9800
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L ++ L P L + L V GE E+ + G + N YG T
Sbjct: 9801 TVLTQTPSAVAMLSPEG--LESVSL-VVVGEACPAEVVDRW------APGRVMVNAYGPT 9851
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T V + + PIG P+D +++LD L P GE++VAGA +A
Sbjct: 9852 ET----TMCVAISAPLAPGMGSPPIGVPVDGAGLFVLDAWLRPVAPGVVGELYVAGAGVA 9907
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
AGYVG G A+RF P +P R+YRTGD G + Y GR D QVK+RG+R+
Sbjct: 9908 AGYVGRSGLTASRFVACPFG-EPG-TRMYRTGDLVCWRPDGQLDYRGRADEQVKVRGYRI 9965
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L EV+ ALA + V++ VV+ G ++G++T G A+ L L Y
Sbjct: 9966 ELGEVQAALAGLDDVEQAVVIAREDRPGGKRLVGYIT---GTADPAE-ARTALAQRLPVY 10021
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P V+ +++IPL NGK+D + L E T S
Sbjct: 10022 MVPTAVVALDAIPLTPNGKIDTRA-LPTPEYTG-------------SRYRAPSNAVEETV 10067
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEISDFLGASTLGE 553
VLG G F+ELGG+S++++ IT + G + + A T+
Sbjct: 10068 AGIYAHVLGVERVGA---DDSFFELGGDSISAMRVITAINASLGVELAVRTLFEAPTVAS 10124
Query: 554 VLSKMSTDPNGGADSKE 570
+ + TD G ++E
Sbjct: 10125 LSRRAQTDTARGGQAEE 10141
Score = 110 bits (264), Expect = 2e-22
Identities = 111/405 (27%), Positives = 176/405 (43%), Gaps = 36/405 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A A KAG Y P+ P R+ +L + V+ + P +
Sbjct: 2017 VVAWWAVTKAGGVYAPVNLDHPVERVASVLHTVDAVCVL--TCGTDEVAGAGPRPILRID 2074
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + HS + DA+ +PL +D A +++TSGSTG+PKGV +S++ + Q
Sbjct: 2075 GL--DLSGHSTEPITDADRRSPLRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRE 2132
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP--QKLVNIERL-- 195
F + + + TF SV E+ G AL++ + L++ +R+
Sbjct: 2133 LFGLGADARV-LMVASPTFDASVGELLLAAGSGAALIVAPPQVYAGEALTALLHNQRVGT 2191
Query: 196 -VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+L PT++ ++ R L L V GE EL G G ++ N
Sbjct: 2192 AILTPTVISTL-------DRGR-LDGLHTLVAVGEACLPELVD------GWAPGRQMFNG 2237
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG +E VT +L + IG P+ +LD L P GE++++G
Sbjct: 2238 YGPSETTIWVT------CARLTAGQPVRIGAPIPGVCARVLDGWLKPVPVGVVGELYLSG 2291
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIR 371
L GY+G A RF NP E R+YRTGD +G + Y GR D Q+K+R
Sbjct: 2292 PALGHGYLGRVDLTAERFVANPFGGPGE--RMYRTGDLVRWTPEGTLDYLGRADNQIKLR 2349
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG 416
G R++L E+E L P V + V G+ +++ +VT G
Sbjct: 2350 GQRIELGEIENTLLACPQVTQAAVTVQDSAAGS-QLVAYVTLDHG 2393
>UniRef50_Q4CA71 Cluster: Amino acid adenylation; n=1; Crocosphaera
watsonii WH 8501|Rep: Amino acid adenylation -
Crocosphaera watsonii
Length = 1049
Score = 199 bits (486), Expect = 2e-49
Identities = 148/450 (32%), Positives = 222/450 (49%), Gaps = 31/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA K G AYVP++P++P RI IL+DA+ S+++ + P +
Sbjct: 518 VIAILAILKVGGAYVPIDPTYPLERINFILEDAQISILLTNQD----------FPNCPVK 567
Query: 80 ELAQEATSHSADEPMDAETLAP-LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L T++ P P L+ D+ LYTSGSTG PK V ++ + NRL W
Sbjct: 568 TLINLQTNYFQSYPEQNTNPTPELSLDNSIYALYTSGSTGNPKAVINTHRGLLNRLNWMQ 627
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLV 196
+ + + + + + KT TF SV E LL+G L+I + +D L + IE+ +
Sbjct: 628 KAYELTPDDRV-LQKTPYTFDVSVWEFLWTLLNGACLVIAKPDGHQDSAYLASLIIEQNI 686
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ S+L + LK +CSGE LS +L + FF+ E L N YG
Sbjct: 687 TTVHFVPSMLQVFLEEQKASQCNSLKRVICSGEALSVDLRNRFFQTIKAE----LNNLYG 742
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DVT + D ++PIG P+DN +Y+L+ +L GE+++ G
Sbjct: 743 PTEAAIDVTACTCQTDDL-----SVPIGLPIDNIQVYVLNAQLQLLPVGVVGELYLGGEG 797
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY+ A F NP RLYRTGDF + G V Y GR D QVKIRG
Sbjct: 798 LARGYLNKPDLTAENFVPNPFKAGA---RLYRTGDFVRYQEDGNVEYVGRIDNQVKIRGV 854
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L+Q P + CVVL G+ +L ++ T ++ + L +
Sbjct: 855 RLELGEIEAILSQHPDIIACVVLAKEFAPGDRRLLAYIQTSQ-TEDISEELRQFLGERIP 913
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKM 462
+Y +P V I +ES PL NGK++ + LL +
Sbjct: 914 NYGIPSVFITLESFPLTNNGKLNTKALLAL 943
>UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Crocosphaera watsonii WH 8501|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Crocosphaera watsonii
Length = 1518
Score = 199 bits (486), Expect = 2e-49
Identities = 167/555 (30%), Positives = 276/555 (49%), Gaps = 57/555 (10%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+I+A+LA +KAG AY+P++ P+ R+ IL+DA+ +++ ++ S +P +
Sbjct: 522 SIVAILAVFKAGGAYLPLDSKMPEERLHGILEDAQVQVLLTEEKL------ASRLPSETA 575
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ L ++ + ++ +++ LT + +A V+YTSGSTG PKGV + + +CN +
Sbjct: 576 QVLCIDSQPTTVEKFQNSDQ--NLTPNDLAYVIYTSGSTGKPKGVAVEHRQLCN---YFN 630
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCE--IWGPLLHGRALLILSRETTRDPQKLVN----- 191
D E + T TF + I+ L G L I+++E +P L
Sbjct: 631 SIIERLDLPETASFATLSTFSADLGNTIIFSALCTGGCLHIIAQERITNPITLAEYFRNH 690
Query: 192 -IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
I+ +VP+ L ++L + + + KL + GE+LS L + + N +
Sbjct: 691 PIDCFKIVPSHLNALLTTVN----AEDILPSKLLILGGESLSWSLVKQIQELQPN---CR 743
Query: 251 LANFYGSTEV-MGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
+ N YG TE +G +T+ V + Q T+PIGRPLDN IYLLDE L P PGE
Sbjct: 744 ILNHYGPTETTIGVLTFKVPQEEHQYAA--TVPIGRPLDNTQIYLLDEYLQPVPLLTPGE 801
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
+++ GANL+ GY RF NP + RLY+TGD G L G++ + GR+D
Sbjct: 802 IYIGGANLSRGYYNRPELTEERFIINPF---DQSTRLYKTGDVGRYLPDGSIEFLGRSDR 858
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVKIRG R++L E+E L+Q P V + VV ++GN ++ +V G+ + H++
Sbjct: 859 QVKIRGFRIELGEIEAVLSQHPSVKQAVVTVPKDEKGNQRLVAYVVL--GSH-NTDHLQD 915
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXX 485
+R L YM+P + + +++IP+ NGK+D + L E ND VA +
Sbjct: 916 FMRIRLPQYMVPHRFVTLKTIPVTANGKIDYKALPAPKE---END--YVAPN-------- 962
Query: 486 XXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDF 545
T+ A + R +S+ F++LGG+S+ SI I+K G +
Sbjct: 963 ---TPQEETLATIWAEILGLER--VSIDDNFFQLGGDSIISIQVISKANQMGLQLTPQQL 1017
Query: 546 LGASTLGEVLSKMST 560
T+ ++ + T
Sbjct: 1018 FEYPTIAQLAAVAKT 1032
>UniRef50_Q1D3K9 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 2048
Score = 199 bits (486), Expect = 2e-49
Identities = 164/553 (29%), Positives = 263/553 (47%), Gaps = 44/553 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAE-PSLVIYDDSAD--PSMFKESGVPFA 76
++ L KAG AY+P++P++P R+ +L+DA P LV + AD PS ++ A
Sbjct: 595 VVGLFGILKAGGAYLPLDPTYPSERLGFMLRDARVPVLVTLERIADRLPSQGEQLLCLDA 654
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
E LA+EATS+ P+T+ ++A VLYTSGSTG PKG + + + N L W
Sbjct: 655 DQEPLAREATSNLE---------VPVTAGNLAYVLYTSGSTGTPKGAMIEHRGVVNYLSW 705
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP-----QKLVN 191
+ ++ V ++++F +V + PL+ G+ + ++ + + + +
Sbjct: 706 STGAYRVAEGSGAPV-HSSISFDLTVTSLLAPLVAGKTVTLVPEDDRLEGLAKALRSKPD 764
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ L PT LR + L + R L V GETLS E A E ++ + G +L
Sbjct: 765 FSLVKLTPTHLRLLARQLDAAALAGQARAL---VIGGETLSAE-ALEPWR--SHAPGTRL 818
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE + V V E + ++ IGRP+ N +Y+LDE L GE++
Sbjct: 819 INEYGPTETV--VGCCVHEATPDDARTGSVAIGRPIANTRLYVLDEHLRLVPVGVHGELY 876
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQV 368
+ G +A GY+ A RF +P P RLYRTGD VL + GR D QV
Sbjct: 877 IGGDGVARGYLDRPELTAERFVPDPFGDVPG-ARLYRTGDRVRRFPDGVLDFLGRRDEQV 935
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG+R++L E+E L Q PGV + VV+ G+ ++ +V GA + +
Sbjct: 936 KVRGYRIELGEIEGVLGQAPGVREVVVVAREDIEGSKRLVAYVVPNEGADVEPEVLRQLA 995
Query: 429 RSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
R+ L +++P V+ ++++PL NGKVDR+ L + D VA
Sbjct: 996 RAKLPEHLVPSVVVPLDALPLSPNGKVDRRALPAPEAIARESHDGYVA-----------P 1044
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
++GA L R R + +R F++LGG+S+ + I + G ++
Sbjct: 1045 RTRAQALLCSLGAELLRLER--VGIRDNFFDLGGDSILGVQLIGRANRAGLHLTPKQLFD 1102
Query: 548 ASTLGEVLSKMST 560
T E+ + T
Sbjct: 1103 HQTFDELAAASGT 1115
>UniRef50_A6VYF8 Cluster: Amino acid adenylation domain; n=1;
Marinomonas sp. MWYL1|Rep: Amino acid adenylation domain
- Marinomonas sp. MWYL1
Length = 3114
Score = 199 bits (486), Expect = 2e-49
Identities = 164/556 (29%), Positives = 274/556 (49%), Gaps = 43/556 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ ++ KAGAAYVP++P +P RI IL+D+ S ++ D P+ E +
Sbjct: 1483 VVGIIGIMKAGAAYVPIDPDYPASRINEILQDSALSTLL-TDVPRPAFASELLDVINIGD 1541
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + ++ + E + + + +A V+YTSG+TG PKGV ++ I RL+
Sbjct: 1542 DDIKSRLNGLLNDNISHEHVC-IRGEDLAYVIYTSGTTGKPKGVMQTHKNI-ERLFEATN 1599
Query: 140 T-FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
T F +S+ + ++ + F SV E+WG L++G L+I + E TRD +K N+ R V
Sbjct: 1600 TDFNFSERDTWILFHSC-AFDFSVWEMWGALVYGGKLVIPNYEETRDAEKFFNLCRDSGV 1658
Query: 199 PTLLRSILMYLALGPASRPLRRLKL-------WVC-SGETLSKELASEFFKYFGNEDGYK 250
L ++ + L +S L+R KL W+ GE L EL + ++K + + +
Sbjct: 1659 TVLNQTPTAFYEL--SSFALKRNKLDKLDKLQWIIFGGEALKPELLTPWWKSY-TDSKPQ 1715
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE VT +L+ SD L IG+PL + Y+LD+ P PGE+
Sbjct: 1716 LVNMYGITETTVHVTLKLLKSSDVL---VRSNIGKPLKDVKAYVLDDLGRPVPPRVPGEL 1772
Query: 311 WVAGANLAAGYVGGGGAN--RFCD----NPHATQPEFQRLYRTGDFGT-LVKGAVLYAGR 363
++ GA +A GY+ RF N A + RLY+TGD LV G + Y GR
Sbjct: 1773 FIGGAGIARGYLNDAELTTARFVSASSINFKALADDQARLYKTGDMVRWLVDGNLEYVGR 1832
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQH 423
D QVKIRG R+++ +VE AL+ + GV+ C V+ + ++G+ ++ S+
Sbjct: 1833 KDNQVKIRGFRIEIGDVENALSAIDGVNHCAVIVSD-THSHKSLVGYYVSETEKELSSTA 1891
Query: 424 IEGKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSX 482
I + L +M+P +I +E++P+ NGK+D++ L E T + E +
Sbjct: 1892 IRRVMLEKLPEHMVPSLLINLETMPVTNNGKLDKKAL---PEPTPLINRKEYIAPRNFVE 1948
Query: 483 XXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
VG +R F+ELGG+S+ SI I+++R++G + +
Sbjct: 1949 SEICSLWEACLDVENVG------------IRDNFFELGGDSILSIRVISEMREKGLELSV 1996
Query: 543 SDFLGASTLGEVLSKM 558
D T+ +L+ +
Sbjct: 1997 KDLFRYQTIENILNNI 2012
Score = 153 bits (370), Expect = 2e-35
Identities = 130/456 (28%), Positives = 214/456 (46%), Gaps = 22/456 (4%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
FS I ++LA K G A+ P++ + P+ ++ LK + VI DD A S + +
Sbjct: 410 FSAIASMLALSKCGVAFSPLDVNLPKAKMFETLKILDALFVITDD-AGISKLPMMPIDYY 468
Query: 77 SFEELAQEATSHSADEPMDAETL------APLTSDSIAIVLYTSGSTGIPKGVRLSYSAI 130
S E++ + + + +D + ++ D I V+ TSG+TG PK V + ++
Sbjct: 469 SVEDMLSNTETSNLSQVLDENQKCVGQFDSSVSGDEIFYVMCTSGTTGRPKAVAVESRSV 528
Query: 131 CNRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV 190
RL R P S ++ + ++L+F SV EIWG LL+G L+++ + D ++
Sbjct: 529 V-RLVVGNRALPLSKETKL-LNVSSLSFDASVLEIWGALLNGAQLVVMG-DALFDFSRME 585
Query: 191 NIERLVLVPTL-LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
++ V TL L S L A + LK + G+ ++ F++ F + D Y
Sbjct: 586 HLITEHQVNTLWLTSALFDQWSDNAPTSMECLKHLIVGGDRVNPISVVSFYEKFKDVDIY 645
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
N YG TE T + + S Q+ +IPIG P++ +Y+LD GE
Sbjct: 646 ---NGYGPTENTTFSTMFKIPRSTQVT-DTSIPIGYPIEQSTVYILDRNQKVLPIGGIGE 701
Query: 310 VWVAGANLAAGYVGG--GGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
++V G +A GY+ +F + RLYRTGD+G +G + Y R+D
Sbjct: 702 IYVGGHGVAKGYLNDTVKSDEKFIFDYFKPDSVTGRLYRTGDYGRWKPEGYIDYIARSDG 761
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILG--FVTTKPGARTSAQHI 424
QVKIRG R++L E+E + + G + + D L F K + I
Sbjct: 762 QVKIRGFRIELGEIESTIVK-SGFARLATVQKIEDESVGSYLAAYFTPLKNSIDNLSDKI 820
Query: 425 EGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L+ L YM+P ++E+E IP+ VNGK+ ++ L
Sbjct: 821 RDHLKECLPEYMVPLHIVELEEIPVNVNGKLSKKDL 856
Score = 136 bits (330), Expect = 2e-30
Identities = 129/460 (28%), Positives = 205/460 (44%), Gaps = 30/460 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADP-SMFKESGVPFASF 78
++ + K+GAAYVP++P +P R+ IL + E I + D S P F
Sbjct: 2570 VVTIFGVLKSGAAYVPIDPDYPIERVEFILSEVESPFFITNSCLDKLCSVNTSATPL--F 2627
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+L+ +S A E ++ S +A ++YTSGSTG PKGV + + ++C L
Sbjct: 2628 LDLSDYESSPEAY----LEDIS--CSHDLAYIIYTSGSTGSPKGVMIEHRSVCAMLESTS 2681
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ +S +++ + + F SV EI+G L +G +I E ++P L N+ +
Sbjct: 2682 QYLDFSKNDKWLSFHS-YAFDFSVWEIFGALFNGATAVIAEVEVIQNPVALRNLMLTEGI 2740
Query: 199 PTLLRSILMYLALGPASRPLRRLKLW---VCSGETLSKE-LASEFFKYFGNEDGYKLANF 254
L + + S L +L V GE L+ + L + + + N
Sbjct: 2741 SILSMTPSAFNNTIVDSNDLSQLSTVRHVVFGGEKLNCDGLRNWYLRNQETLSNTDFINM 2800
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE+ T+Y L + T IGRPL Y+L++E+SP G+++++G
Sbjct: 2801 YGITEITVHATFYRLLFDKEFG--STSVIGRPLKGLKAYVLNDEMSPVPIGVKGKLYISG 2858
Query: 315 ANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
LA GY+ F D E +RLY TGD G + Y GR D Q+ IR
Sbjct: 2859 YGLARGYLNKQTLTEESFIDYTF-LNGETRRLYDTGDIVRWNDSGELEYFGRKDKQLSIR 2917
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS---------AQ 422
G R+++ E+E L + V ++ GN I FV R + +
Sbjct: 2918 GFRIEIGEIEANLRRSALVRDTQLVAREDSEGNTYISAFVIPLLDGRQALDREKQNELIR 2977
Query: 423 HIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLK 461
I+ +LR L YM+P V PL NGK+D + L++
Sbjct: 2978 QIKSELRLYLPEYMIPTTWALVSDWPLTTNGKIDTERLIQ 3017
>UniRef50_Q4JTA1 Cluster: Non-ribosomal peptide synthetase; n=1;
Corynebacterium jeikeium K411|Rep: Non-ribosomal peptide
synthetase - Corynebacterium jeikeium (strain K411)
Length = 3618
Score = 199 bits (485), Expect = 3e-49
Identities = 166/538 (30%), Positives = 260/538 (48%), Gaps = 55/538 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ ++AT AG ++VP++PS+PQ R + DA S V+ D+
Sbjct: 116 VVGIVATLLAGGSFVPLDPSWPQARRESVTHDASLSFVLTPDNC---------------- 159
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L ++A D E P ++DS+A V++TSGSTG PKG + + AI RL WQ
Sbjct: 160 ALTEDALF---DLDATRELFTPPSTDSVAYVIFTSGSTGRPKGAMIRHGAIVERLLWQRD 216
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ ++ ++K L F S+ EI+ PL+ G +++ + +DPQ+L + V
Sbjct: 217 QILFFGRDDASLFKAPLAFDISINEIFLPLVCGGRVVVAAPGVEQDPQRLARLIHREGVT 276
Query: 198 VPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L+ S+L + L + L L+ C GE L++ L F+ F + L + YG
Sbjct: 277 FAYLVSSVLDVMLKQAEGTNLLDSLRHVWCGGEMLTQAL----FRRFRQQLAIPLYHGYG 332
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E V+ +V+ D+ L +I + P NC +Y+LDE L D E GE++VAG
Sbjct: 333 PAEATIGVS-HVIYRDDEDRLNTSIGVANP--NCRLYVLDEHLRVVPDQEIGELYVAGFL 389
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY+ G A+RF + A+ + R+YRTGD G++ + GR D QVKIRG
Sbjct: 390 LAKGYINAPGLTASRFVADVFAS--DGTRMYRTGDLVRRHNDGSLEFVGRADNQVKIRGM 447
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L +VE AL P V+ V+ +LG+VT G +A I L
Sbjct: 448 RLELEDVESALVGHPDVEAASVIA-----REGRLLGYVTVTAGLVGAA--IRSWCAEVLP 500
Query: 434 HYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P +I V + +P NGKVDR+ L + + ++ DA + D
Sbjct: 501 EYMVPAIITVMDELPRTANGKVDRKALPE--PDWSSLTDAPADAERD--------GETVA 550
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
+ LG +A G + F+++GG+SL +I ++ L RG V + D A T
Sbjct: 551 LLAEAMAEALGVSAVGA---ETDFFDIGGDSLRAITLVSALGRRGVEVSVGDIFSART 605
Score = 186 bits (453), Expect = 2e-45
Identities = 133/448 (29%), Positives = 211/448 (47%), Gaps = 18/448 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+LAT + YVP++P PQ R+ IL+D +P V+ SA+ + + P
Sbjct: 1628 VAAILATTMSAGTYVPVDPLSPQARVELILEDCQPDAVLVSPSAEKMVSELVDCPVL--- 1684
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E T +P + + ++ IA V+YTSGSTG PKGV ++++ + L R
Sbjct: 1685 -VVSEQTMSGEAKPPAGRSASVARANDIAYVIYTSGSTGRPKGVAVTHANVTAMLG-NAR 1742
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ E++ + F SV E+W L G +++ R P+ + R +
Sbjct: 1743 SHVEFSQEDVWSISHSFAFDFSVWEMWAALSSGGRAVVMPYALMRSPEDAAEVLRAEAIT 1802
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L ++ + AL P ++ + GE L + + N + N YG TE
Sbjct: 1803 VLSQTPTAFAALEPHLGQDSAVRTVIFGGEALEARAEAAYCSAHPN---VRFINMYGITE 1859
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
VT + E S+ + PIGRP+D Y+LD +L P + E G ++VAG + A
Sbjct: 1860 TTVHVTAH--ECSENAGEARS-PIGRPMDGLRTYVLDAQLQPVQPGETGMMYVAGPQVTA 1916
Query: 320 GYVG--GGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIRGHRVD 376
GY G A+RF +P R+Y + D L G + Y GR D QV++RG+RV+
Sbjct: 1917 GYWGLASTTASRFVADPFVGGG--ARMYCSNDMAKVLNNGHLDYVGRADRQVQLRGYRVE 1974
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGN-PEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
L E+E AL +V GV + V+ L G P L ++ A+ R AL Y
Sbjct: 1975 LGEIESALEKVSGVREATVVVVDLPEGQVPGALLITDSRADAKAITSRAAAAARDALPAY 2034
Query: 436 MMPQVIEVES-IPLLVNGKVDRQGLLKM 462
M+PQ+ V + +P +NGK D + +L +
Sbjct: 2035 MVPQLFAVSTQVPQTINGKRDERAILDL 2062
Score = 131 bits (316), Expect = 8e-29
Identities = 135/464 (29%), Positives = 205/464 (44%), Gaps = 50/464 (10%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++ALL AG Y P++ + P GR+ +++D++P+ + D S+ M + +P
Sbjct: 3093 SVVALLGALWAGVRYAPLDLTHPDGRLRVLVEDSQPAAALVDSSSRERMERIGALPCVDV 3152
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
AT+H T A + D A ++YTSGSTG PKGV + + + N L
Sbjct: 3153 TTADSHATTH---------TPAAVPGDD-AYLMYTSGSTGKPKGVVIKHRGLHNMLDNHR 3202
Query: 139 RTF--PYSDSEEICVWKTALTFV-DSVCEIWGPLLHGRALLILSRETTRDPQKLV----- 190
R P + A++F D E L+ G + I S + RD +V
Sbjct: 3203 RKIFAPAAADGRTLRIAHAISFAFDMSWEELFWLVEGHEVRIFSEDLRRDAAAMVEAIRA 3262
Query: 191 -NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
++ + + PT+ + LA G R +L + GE +S + E + + GY
Sbjct: 3263 HQVDVINVTPTVAEQL---LAEGMLESGAHRPRLVLLGGEAVSHGV-WETLRKADDVRGY 3318
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
N YG TE Y + D T IG P+D A ++LD L P PGE
Sbjct: 3319 ---NLYGPTE------YTINALGAGTDESATPVIGMPVDRTAAFVLDPWLRPVPTGAPGE 3369
Query: 310 VWVAGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDA 366
+++AG+ LA Y G A+ P E R+YRTGD + G Y GR+D
Sbjct: 3370 LYLAGSGLAQEYHGLAARTASSMVACPWGAPGE--RMYRTGDIVRVRADGMFEYLGRSDD 3427
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLD--RGNPEILGFVTTKPGARTSAQ-- 422
QVKIRGHRVD +V A+++ GVD ++ C + + +L P R + Q
Sbjct: 3428 QVKIRGHRVDPGDVSAAVSR--GVDPRILHCVTVPVRISDATLLACHLVAPQLRDADQGE 3485
Query: 423 ------HIEGKLRSALTHYMMPQVIE-VESIPLLVNGKVDRQGL 459
+ LR L YM+P V+ +P+ NGK D L
Sbjct: 3486 RQSFLTGVRNALREELPSYMIPDRWSIVDELPVTSNGKTDLAAL 3529
>UniRef50_Q643C7 Cluster: Mannopeptimycin peptide synthetase MppA;
n=1; Streptomyces hygroscopicus|Rep: Mannopeptimycin
peptide synthetase MppA - Streptomyces hygroscopicus
Length = 2747
Score = 199 bits (485), Expect = 3e-49
Identities = 162/548 (29%), Positives = 253/548 (46%), Gaps = 39/548 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIY-----DDSADPSMFKESGVP 74
I+A+LA K+GA Y+P++P +P RI +IL DA P I D DP SG
Sbjct: 71 IVAILAVLKSGAGYIPIDPEYPADRIAYILGDARPVATITTAEVRDGLPDPDT--GSGTD 128
Query: 75 FASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
+ +E E A P A AP ++++ A V+YTSGSTG PKGV + +S + L
Sbjct: 129 WLILDESGYEQEPAGA-RPQPAPA-APRSAENPAYVIYTSGSTGRPKGVVIPHSNVGRLL 186
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-- 192
+ + D +++ + F SV EIWG LLHG L+++ TR P + +
Sbjct: 187 SSTAHWYGF-DEQDVWPLFHSFAFDVSVWEIWGALLHGGKLVVVPHAVTRAPADFLRLLV 245
Query: 193 -ERLVLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG 248
ER+ ++ P+ ++ PA L+ V +GE L +++++ ++
Sbjct: 246 EERVTVLNQTPSAFYQLMAADRENPALGAQLALRYVVFAGEALDLGKLADWYERH-DDRA 304
Query: 249 YKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPG 308
L N YG TE ++ L+ + +G L + ++LDE+L P G
Sbjct: 305 PTLVNMYGITETTVHSSFLALDKEGAAGATGSA-VGVALPDLTFHVLDEDLRPVPVGAEG 363
Query: 309 EVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTD 365
E++VAG LA Y G G A RF P P R+YR+GD L G + Y R+D
Sbjct: 364 ELYVAGPGLARNYAGRPGLTAERFVACPFG--PPGARMYRSGDLVRPLPDGGLEYLRRSD 421
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
QVKIRG R++L E+ ALAQ P VD+ V+ G ++ +V AR + +
Sbjct: 422 DQVKIRGFRIELGEISHALAQDPSVDQATVVVRDEASGERRLVAYVVPAGSARPTPSRLR 481
Query: 426 GKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXX 484
L + L YM+P V + PL NGK+DR+ L ++ DA+ A +
Sbjct: 482 AALATRLPGYMVPTAFHVMPAFPLTANGKLDRRAL--PAPTRQDSVDADYAAPEGATEEA 539
Query: 485 XXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEIS 543
+GA F+ELGG+SL+ + ++++R G + +
Sbjct: 540 LAAIWREVLGVEQIGA------------DDDFFELGGDSLSVVRALSRMRTGLGLRLTAA 587
Query: 544 DFLGASTL 551
+F T+
Sbjct: 588 EFFATPTV 595
Score = 176 bits (429), Expect = 2e-42
Identities = 138/446 (30%), Positives = 216/446 (48%), Gaps = 27/446 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+L T KAGAAYVP++P FP R+ +L ++ P++++ + +G+P
Sbjct: 2220 VVAILGTLKAGAAYVPLDPEFPAQRLATMLSESRPAVLLTQEHL------LAGLPPTDAR 2273
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + + A ++ + +A V YTSGSTG PKGV + + ++ N + R
Sbjct: 2274 VVCVDRDLAAIEAHPTAAPVSGGDAGDLAYVTYTSGSTGRPKGVMVEHRSLFNIITEAGR 2333
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + + T ++F V E++ L G L+I E + P L R +
Sbjct: 2334 LYDLGPDSRMLQFYT-MSFDGGVWEVFLTLTAGATLVIADPEARQSPAHLAEQLRAESIT 2392
Query: 200 TLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L + L AS P +R L L +G+ L+ ELA E+ + G +L N YG +
Sbjct: 2393 ALTLPPAVASVLDAASLPGIRSLGL---AGDVLAPELAREWAR------GRRLFNIYGPS 2443
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E V L D +P+G P+ N ++LDE L+ GE+++ GA LA
Sbjct: 2444 EATLSVA---LHRVDPGAAGRQVPLGPPVPNTRFHVLDERLAVVPVGVTGELYIGGAGLA 2500
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGHRV 375
GY+G A RF +P P RLYRTGD +G + +AGR D QVKIRG+RV
Sbjct: 2501 RGYLGRPDLTAQRFVADPFG--PPGSRLYRTGDLIRWTPQGRLEFAGRVDNQVKIRGYRV 2558
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK-PGARTSAQHIEGKLRSALTH 434
+ EVE AL + PGV + VV+ D G+ ++ +V G + L L
Sbjct: 2559 EPAEVESALLRQPGVAEAVVIARDDDTGHKRLVAYVVPDGSGTAPERAALLRALGGQLPG 2618
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM+P ++ + +PL GKVD + L
Sbjct: 2619 YMVPSALVTLPELPLGPTGKVDVRAL 2644
Score = 165 bits (400), Expect = 5e-39
Identities = 159/560 (28%), Positives = 239/560 (42%), Gaps = 43/560 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA KAG AYVP P R+ H+L++ V+ + + +
Sbjct: 1145 IVAMLAVLKAGGAYVPTALDTPAARLGHLLEETGTP-VLLTTARQAGALPPTEASVIDLD 1203
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ H +P A + +A ++YTSGSTG PKGV + +SA+ + W
Sbjct: 1204 AAGPDIARHPEHDPQVATR-----PEDLAYIVYTSGSTGRPKGVAVPHSALTDYCAWHND 1258
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLVL 197
E+ L F +V E+W L G + +ET DP LV E
Sbjct: 1259 ALDVGP-EDRGSSVVGLAFDVAVGEVWPYLCAGARVDQPDQETLDDPTALVEWFAENGTT 1317
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V L + L L A+ RL+ + G++L + + L N YG
Sbjct: 1318 VAYLPTPRIESL-LDVAAITTTRLRTVLVIGDSLRRRPQPGL--------PFTLLNAYGP 1368
Query: 258 TEVMGDVTYYVLE--GSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
E T V+E G D P+I G PL N A Y+LD+ L P PGE+++AGA
Sbjct: 1369 AEATVAATQAVVEPLGPDAPAGLPSI--GAPLYNTAAYVLDDRLCPVPVGVPGELYLAGA 1426
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
LA GY G A RF P P R+YRTGD L G + + GR D QVK+RG
Sbjct: 1427 GLAQGYQGRPDLTAERFVGCPFG--PPGTRMYRTGDIVRWLPDGTLDFLGRIDNQVKLRG 1484
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
+R++L E+E LA+ + + V G ++ ++ G + + G + S L
Sbjct: 1485 YRIELGEIESVLARREELSQVFVTVREPSPGRRSLVAYLVADRGTAPDPEELAGYIASVL 1544
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P + ++++PL NGK+DR+ L + E A VA +
Sbjct: 1545 PEYMVPSSFVLLDALPLTANGKIDRRALPEP-EPAGGEGAAYVAPGNEVEETLAAIW--- 1600
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
VLG G ++ F+ LGG+S++ + T + R G + D T+
Sbjct: 1601 -------AEVLGVERVG---VQDNFFALGGDSISGLQTAVRARRAGLRLASKDLFQRQTI 1650
Query: 552 GEVLSKMSTDPNGGADSKEA 571
LS + T AD+ A
Sbjct: 1651 A-ALSPVVTVERTTADADPA 1669
>UniRef50_Q0TGF7 Cluster: Probable peptide synthetase protein; n=5;
Enterobacteriaceae|Rep: Probable peptide synthetase
protein - Escherichia coli O6:K15:H31 (strain 536 /
UPEC)
Length = 1598
Score = 199 bits (485), Expect = 3e-49
Identities = 147/456 (32%), Positives = 227/456 (49%), Gaps = 35/456 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A KAG AY+P+ + P+ RI +IL ++ +I D D +P +
Sbjct: 79 LIAIFAIVKAGGAYLPLAYNAPRSRIENILSNSGAVCLIGTDDGD-----RWPIPRVEID 133
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A A P P + +A ++YTSGSTG+PKGV ++A+ NR+ W
Sbjct: 134 SAAVSAM------PTTDLRYRP-HARQLAYIIYTSGSTGVPKGVATEHAALLNRIVWMQN 186
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
+P S S+++ KT TF SV E++ ++G ++++L DP+ L I+R
Sbjct: 187 AYPIS-SQDVLFQKTVYTFDVSVWEMFWWAMYGASVVLLPSGLESDPRTLARLIQRHRVS 245
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP++L + YL + R L+L SGE L+ + F++ D L N
Sbjct: 246 VVHFVPSMLNLFVEYLEMKQDPRLTASLRLVFSSGEKLTVHSVARFYQSVAQGD---LIN 302
Query: 254 FYGSTEVMGDVTYY-VLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE DV+++ L G D Y IPIG+ +D C +Y+LD+ +P D E GE+++
Sbjct: 303 LYGPTEAAIDVSHHRCLRGYD----YDDIPIGQAIDGCRLYVLDDHGNPVADGEEGELYL 358
Query: 313 AGANLAAGYVGGGGANRFCDNPHATQPEF---QRLYRTGD--FGTLVKGAVLYAGRTDAQ 367
AG LA GY+ C H T +RLY+TGD + + Y GR D Q
Sbjct: 359 AGIGLARGYLNNVALTDRCFTIHPTLRHLGKPERLYKTGDLVWRDGESQQIHYIGRNDFQ 418
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
+KIRG RV+L E+E + PGV + VV+ D N I FV + +A +
Sbjct: 419 IKIRGLRVELGEIEAHAMRFPGVQQAVVVADQDDPDNQLIYAFVVSSVPLNLAA--LMDA 476
Query: 428 LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKM 462
L L YM+P +++ + +PL NGK R+ LL +
Sbjct: 477 LSKNLPAYMLPNRLLAMSELPLSDNGKCCRKTLLDL 512
Score = 140 bits (338), Expect = 2e-31
Identities = 123/448 (27%), Positives = 204/448 (45%), Gaps = 20/448 (4%)
Query: 15 FYFSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVP 74
F F I+A LA GA+YVP++ + P R IL A P +++ + +P
Sbjct: 1043 FCFELIIAQLAILSLGASYVPLDGNAPAARNALILAQATPCMLLVAQPLESP--HGLTIP 1100
Query: 75 FASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
+ L + S + P ++AP D A+V++TSG+TG PKGVRLS + N L
Sbjct: 1101 WV----LVPDWRSLLTEIPNLPVSVAPDALDCDAVVIFTSGTTGQPKGVRLSQRNLVN-L 1155
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER 194
F + +++ + T++ V E+ L G L++ + + D L+ +
Sbjct: 1156 TASFISSYQVTHQDVLLPITSVASASFVGEVLPLLAAGGTLVLAQKAQSLDSDALIALLA 1215
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
V L + + +L ++ + L+L++C GE L E + + + N
Sbjct: 1216 SQRVTILSTTPSLSASLSVLAQSMGSLRLFLCGGEALEYEQIAPLLPHMA------VVNG 1269
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE TY+ + + + +PIGRP+ N Y++D GE+ +G
Sbjct: 1270 YGLTESGICSTYFPVAKRREQET-GALPIGRPIQNTQAYVVDAYNRLVPPGACGELCFSG 1328
Query: 315 ANLAAGYVGG-GGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
++ GY+ RF + P P R+ +TGD G + Y GR D QV+IRG
Sbjct: 1329 LGISPGYLDARQDPERFVELPE--YPGV-RVLKTGDRARWATDGMLFYLGRQDRQVQIRG 1385
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
+RV+L ++E L Q P + V P ++ F + G AQ + L L
Sbjct: 1386 YRVELGDIESLLKQHPDIADAWVDVRRNAAATPLLVAFYCSVNGVALDAQQLRVWLSLRL 1445
Query: 433 THYMMPQV-IEVESIPLLVNGKVDRQGL 459
+M+P + + + ++PL VNGK+D Q L
Sbjct: 1446 PLHMLPLLYVPLSAMPLGVNGKIDPQCL 1473
>UniRef50_A0PTU8 Cluster: Non-ribosomal peptide synthetase MbtE;
n=1; Mycobacterium ulcerans Agy99|Rep: Non-ribosomal
peptide synthetase MbtE - Mycobacterium ulcerans (strain
Agy99)
Length = 1670
Score = 199 bits (485), Expect = 3e-49
Identities = 150/447 (33%), Positives = 232/447 (51%), Gaps = 36/447 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA KAGAAY+P++P++P RI +++ DA P VI P +
Sbjct: 554 IVAMLAVLKAGAAYLPIDPAYPDERIDYLITDARPQTVI----GRPEL------------ 597
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
++A+ A + ++D P+ D + L PL +A V+YTSGSTG PKGV +S+ AI +
Sbjct: 598 DVAERAAADNSDLPLSDGDRLRPLRPGHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFV 657
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
+ + +E+ + ++++F S+ +I+ L G L++ + D + ++ R V
Sbjct: 658 AEWTMT-AEDRWLQFSSVSFDASLADIFVTLFLGAQLIVPKPDAFGDISYVADLISRRGV 716
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V L+ S+L L L P + R+L+ GE L E+A F YF E L N YG
Sbjct: 717 TVLHLVPSMLSTLLLLPQVQQWRQLRHVPVGGEALPGEVADRFAGYFDAE----LRNHYG 772
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE + T+ ++ GS + +PIG P N Y+LDE+L P D GE+++ G+
Sbjct: 773 PTEAVVCSTHMLVTGSHGARV---VPIGVPNRNVYAYVLDEQLHPVPDQVVGELYLGGSQ 829
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY+G A RF +P P RLYRTGD G + + GR D QVKIRG
Sbjct: 830 LARGYLGRPTLTAQRFIADPF--NPG-MRLYRTGDLVRRNHCGELEFVGRADEQVKIRGF 886
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L EVE + P V C+V+ + G P + ++ A+ + I +A+
Sbjct: 887 RIELGEVESVITTHPAVRHCLVVAEETEAG-PMLAAYL-VPAAAQVDLEEIRAHTAAAVP 944
Query: 434 HYMMPQVIEV-ESIPLLVNGKVDRQGL 459
YM+P V IP+ V+GK+DR+ L
Sbjct: 945 EYMVPGAFAVIPEIPMTVSGKLDRRAL 971
>UniRef50_Q840C8 Cluster: Catechol siderophore synthase DhbF-like
protein; n=1; Acinetobacter baumannii|Rep: Catechol
siderophore synthase DhbF-like protein - Acinetobacter
baumannii
Length = 2383
Score = 198 bits (484), Expect = 4e-49
Identities = 155/469 (33%), Positives = 238/469 (50%), Gaps = 42/469 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+A+LA +AGAAY+P++ P RI +L+DA+ LVI + D + + +F +
Sbjct: 1597 IAILAVIEAGAAYLPIDLQHPSERIKFMLQDAKSKLVI-GEQKDLAAIAHPSIATFAFND 1655
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
L E D + + +T A ++YTSG+TG PKGV +S+ AI NR+ W
Sbjct: 1656 LFDET---KVD--LSSYKTTVITPQHPAYLIYTSGTTGQPKGVMVSHHAIVNRILWMQSE 1710
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IER 194
+P S ++ I + KT TF SV E + L G L++ + RDP L++ I
Sbjct: 1711 YPLSANDTI-LQKTPCTFDVSVWEFFWSYLVGARLVMAPVDAHRDPLALLSLIQKYQITT 1769
Query: 195 LVLVPTLL-----RSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
L VP++L + + + S P+RR+ CSGE L LA F ++F E
Sbjct: 1770 LHFVPSMLAVFENAATEILSSAQLQSLPIRRV---FCSGEALPTALAKSFTEHFSCE--- 1823
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYP---TIPIGRPLDNCAIYLLDEELSPTRDSE 306
L N YG TE DV+Y L L+P ++ IG P+ N +Y+LD+ L P
Sbjct: 1824 -LHNLYGPTEAAVDVSYM----DATLGLHPEESSVAIGYPVWNTQLYILDQYLRPVPVGV 1878
Query: 307 PGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGR 363
GE+++AG LA GY+ A RF NP A QR+YRTGD G++ Y GR
Sbjct: 1879 DGELYLAGHQLAMGYLHRADLTATRFVANPFAAG---QRMYRTGDIARWHADGSIQYVGR 1935
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCV-VLCYGLDRGNPEILGFVTTKPGARTSAQ 422
D Q+KIRG R++L E+E+ L + +D V + ++ + +++ ++ T A +
Sbjct: 1936 ADDQLKIRGQRIELGEIEQQLCLISSLDVVVHPISSEQNKADVQLVAYLQTT--APVDIE 1993
Query: 423 HIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNND 470
++ +L L YM+P + VE PL NGK+DR+ L + N N +
Sbjct: 1994 KLKKQLAKQLPAYMVPTHYVLVEKFPLSHNGKLDRKALPQPKINPTNTE 2042
Score = 128 bits (309), Expect = 6e-28
Identities = 146/578 (25%), Positives = 251/578 (43%), Gaps = 65/578 (11%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++ +L+ +GA+++P++ +P R+ + +DA P V+ + + +
Sbjct: 540 SVVVMLSVLNSGASFLPLDLDYPIDRMQMMCEDANPLFVLTTQELAQKLPQNIPQLYLDH 599
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E++ + A + + AE +A V++TSGSTG PKGV ++ ++ N +
Sbjct: 600 EDVQIQIRKQDASD-IPAEN-RKFNFQDVAYVIFTSGSTGRPKGVMNTHGSLLNLILTHK 657
Query: 139 RTFPYSDSEEI----------CVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK 188
T + E + + +F S +++ +L G+ L I RD
Sbjct: 658 PTIYWPVLEAVNQRFPNRPLRAAHTHSFSFDSSWLQVFW-MLWGQELHIFDENMRRDAFG 716
Query: 189 LVN------IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKY 242
LV I+ L L P+ ++ G + + L + GE L ++
Sbjct: 717 LVQEIQQRQIDTLDLPPSFCAQMMTN---GLFTENQHQPTLILIGGEAAPLAL----WQQ 769
Query: 243 FGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPT 302
+ N YG TE D L+ + + P I G P+ N Y+LD L
Sbjct: 770 LNAQPELFAHNLYGPTEYTVDTFRAELKQTAR----PVI--GNPIGNTQAYVLDRHLQRC 823
Query: 303 RDSEPGEVWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVL 359
GE++++G +A GY+G A RF NP QR+YRTGD G +
Sbjct: 824 PTGVIGELYISGFGIANGYLGRADLSAARFVANPFE---HGQRMYRTGDLVRWNSVGKLE 880
Query: 360 YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP---G 416
+ GR D Q+KIRG+RV++ EVE AL+ + V+ VV+ ++ + +LG+ K
Sbjct: 881 FMGRCDDQIKIRGYRVEIGEVENALSILANVESAVVIAEPINNSH-RLLGYCVVKNIELD 939
Query: 417 ARTS---AQHIEGKLRSALTHYMMPQVIEVES-IPLLVNGKVDRQGLLKMYENTNNNDDA 472
+TS +Q +LR L YM+P + V S P V+GKVD++ L + ++
Sbjct: 940 EKTSEQLSQQYLSQLRQNLPEYMVPSALTVMSEFPRNVSGKVDKKALPRPQIRAHSRMPE 999
Query: 473 EVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITK 532
+ C + +VL A G + F+ GG+S+++I T+
Sbjct: 1000 TPEQQLLCQ---------------IIASVLKLDAIG---IDDDFFMTGGDSISAIMLCTQ 1041
Query: 533 LRDRGYYVEISDFLGASTLGEVLSKMS-TDPNGGADSK 569
LR RGY + SD T+ + +++ D A SK
Sbjct: 1042 LRQRGYGLRPSDVFQFKTVAAIAQQLTRLDEQQAAISK 1079
>UniRef50_A5EHY6 Cluster: Non-ribosomal peptide synthase; n=2;
cellular organisms|Rep: Non-ribosomal peptide synthase -
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 3962
Score = 198 bits (483), Expect = 5e-49
Identities = 149/458 (32%), Positives = 233/458 (50%), Gaps = 42/458 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ L+ KAG AYVP+EP P R+ +L D++ +++ +A + F P + E
Sbjct: 3172 IVGLMGILKAGGAYVPLEPDVPDDRLQFMLADSQAPVLV-TTAALANKF-----PQFTGE 3225
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIA----IVLYTSGSTGIPKGVRLSYSAICNRL 134
+A D+PM D+ET T +++A + YTSGSTG PKGV + S + NR
Sbjct: 3226 VIA-------LDDPMLDSETACDPTREAVADPLLYIAYTSGSTGRPKGVMVQQSTVLNRF 3278
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--- 191
W +R+ P +D +E+ +++ FVD+V E++ L G ++ S E RDPQ++V+
Sbjct: 3279 HWLWRSLPLAD-DEVGSQISSINFVDAVWEVFSRLARGIPFVVCSDEVVRDPQRMVDALA 3337
Query: 192 ---IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG 248
+ RL VP+LL S+L + + L L+ +CSGE L ELA F
Sbjct: 3338 RHRVTRLEPVPSLLASLLDNVP--DIAERLPHLRYCICSGEILPVELARRF---RATMPA 3392
Query: 249 YKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPG 308
+L N YGSTE V + + ++ +P+G P+ N I +LD P G
Sbjct: 3393 VRLFNRYGSTEAT-SVLWQEVVNTEAYG--ANVPVGHPVQNVGICILDRRRRPLPHGIAG 3449
Query: 309 EVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTD 365
++V G +A GY G A RF P TQ R Y TGD G++ GR D
Sbjct: 3450 SLYVYGDAVARGYHGRPDLTAERFVTLPLITQE--VRAYYTGDLARQRADGSIEVLGRDD 3507
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART--SAQH 423
Q+ I G+R++ E+E AL ++ G+ CV + + G+ +++ F A T S Q
Sbjct: 3508 NQLSIHGYRIEPGEIETALGRLAGIRDCVAVVRDIG-GSRQLVAFYAEADDAGTALSPQA 3566
Query: 424 IEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLL 460
+ L L YM+P + +++ ++PL +NGKVDR+ L+
Sbjct: 3567 LRNHLAGQLPAYMVPSLFVKLAALPLTINGKVDRKSLV 3604
Score = 191 bits (465), Expect = 7e-47
Identities = 162/552 (29%), Positives = 252/552 (45%), Gaps = 56/552 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA KAG A+VP++P +P R+ +++D+ LV+ A P ++ V +
Sbjct: 1658 VIAILAILKAGGAWVPLDPDYPAERLRFMIEDSAAELVL----ASPKAARDVAVLQSPQR 1713
Query: 80 -ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN--RLWW 136
L E T S D+ T P + A V+YTSGSTG PKGV + A+ N W
Sbjct: 1714 LLLIVEPTDGSGDDRPPPATTGPADA---AYVIYTSGSTGRPKGVACVHRAVINFCHEWQ 1770
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------ 190
R D+ + ++L+F SV EI+ LL G A+ +L ++T D +
Sbjct: 1771 SKRAIAPGDAGTL---TSSLSFDVSVYEIFSNLLFGAAVHLLDKDTILDADRFARYLRDQ 1827
Query: 191 NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
I+ L P LL ++ +A A+ L+RL + V L ++ G
Sbjct: 1828 RIQNCYLPPHLLTAVASLVAADGANYALKRLMVGV------EPPLEQAMWRIKQAVPGAA 1881
Query: 251 LANFYGSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
+ N YG+TE +G + YYV + + PIG P N YLLD+ L P GE
Sbjct: 1882 VVNGYGTTETTIGSIAYYVERDTGRSG---NAPIGVPFQNQTAYLLDKRLRPVPLGAIGE 1938
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPE-----FQRLYRTGDFGTLVKGAVLYA- 361
+++ G ++AGY+ A RF DNP + P+ R+YRTGD G ++ L
Sbjct: 1939 IYIGGDGVSAGYLNRPELTAERFMDNPFQSLPDRLAGRNARIYRTGDLGRMLPDRQLECL 1998
Query: 362 GRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA 421
GR D Q+KIRG+RV+ E+E +A PGV + V+ +D G L P +
Sbjct: 1999 GRIDTQIKIRGYRVEPSEIEAVIAACPGVTQSAVIV--VDSGAARRLVGYYAAPSGQPDE 2056
Query: 422 QHIEGKLRSALTHYMMPQVI-EVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDC 480
Q + +L + L YM+P V+ ++ + L NGK+DR+ L T + D D
Sbjct: 2057 QTVRARLAALLPPYMVPAVLMRLDRLQLSPNGKIDRRALPLPASATPDKRDLSAPRD--- 2113
Query: 481 SXXXXXXXXXXXXXXXTVGAVLGRAAR-GTLSLRSGFYELGGNSLNSIYTITKLRDRGYY 539
+ AV + + + F+ LGG+S+ +I I + R G
Sbjct: 2114 ------------DTEAALAAVWRTVLKLDQIGIDEDFFALGGDSILTIQVIARARQMGLE 2161
Query: 540 VEISDFLGASTL 551
+ S A T+
Sbjct: 2162 LSASQLFAAPTI 2173
Score = 137 bits (331), Expect = 1e-30
Identities = 127/448 (28%), Positives = 211/448 (47%), Gaps = 42/448 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A LA KAGAAY+P+ P P R+ +++DA P L+I D +F VP +
Sbjct: 607 IVAFLAVLKAGAAYLPLAPDLPSERLRFMVEDAAPRLIIVTDQTS-GLFDSMPVPQLLVD 665
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++A + +A P P D +A V+YTSG+TG PKG + + ++ N Q
Sbjct: 666 MQHEDAHADAAARP-------PRRHD-LAYVIYTSGTTGRPKGALIEHGSLANLARAQRD 717
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
F + ++ A++F S+ I L G L ++ + +P+ + + + +
Sbjct: 718 LFGLEPGARVLLY-VAMSFDVSIGAIATALAAGATLHLVPQRLMAEPEAIAAMIRDHAID 776
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ L +I L + P + V GE +++ + Y+ + ++ N YG
Sbjct: 777 LVELPATIAQQLPRRQDAAP----RTLVIGGEVCPQDVLA----YWSGQ--CRVINAYGP 826
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIP--IGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
+E VL +D + P P IGRP+ N + +LD PGE+ + GA
Sbjct: 827 SETA------VLATTDAI-CKPITPHVIGRPIANVQVRILDGNDRFCPIGVPGEICIGGA 879
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
+A GY+G A +F +P T P RLYR+GD G G + + GR D Q+K+ G
Sbjct: 880 GVARGYLGRPDLTARQFMADP--TGP--GRLYRSGDIGRWRSDGRLEWLGRVDEQIKLNG 935
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++ E+ R + Q GV VL D + ++GF P A + LR+ L
Sbjct: 936 LRIEPGEIARVMEQHEGVTSAHVL-VDQDGRSSRLVGFYAAAPEFDEPA--LRHHLRARL 992
Query: 433 THYMMPQVI-EVESIPLLVNGKVDRQGL 459
YM+P ++ ++++P+ NGK+D + L
Sbjct: 993 PAYMVPSLLMRLDALPVGPNGKLDPRAL 1020
>UniRef50_A3KI35 Cluster: Putative peptide synthetase; n=1;
Streptomyces ambofaciens ATCC 23877|Rep: Putative peptide
synthetase - Streptomyces ambofaciens ATCC 23877
Length = 2873
Score = 198 bits (483), Expect = 5e-49
Identities = 159/554 (28%), Positives = 253/554 (45%), Gaps = 28/554 (5%)
Query: 22 ALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEEL 81
ALLA K GAAY+P++P P R+ +++DA P L++ + + V EE+
Sbjct: 522 ALLAVLKTGAAYLPLDPGHPAERLRLVVEDAAPVLLVTERAHAHLAGDALPVVRLDDEEV 581
Query: 82 AQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTF 141
A + A + DA+ P+ IA +++TSGSTG PKGV + ++ + F
Sbjct: 582 AADLARRGAADLTDADRRGPVRPSDIAYIIHTSGSTGRPKGVPVPHANVVRLFASAAEHF 641
Query: 142 PYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVLVP 199
+ ++++ + F SV EIWG LLHG ++++ +R P++++ + V V
Sbjct: 642 SFG-ADDVWTLFHSYAFDFSVWEIWGALLHGGRVVVVPYAVSRSPREVLELLHREGVTVL 700
Query: 200 TLLRSILMYLALGPASR--PLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
S L A R L+ V GE L + G D L N YG
Sbjct: 701 NQTPSAFEQLVDADAERGGDAGALRYVVLGGEALRPARLRPWADRHGL-DRPVLVNMYGI 759
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE VT++ L +D D IG PL + ++LLD+ P GE++V+GA +
Sbjct: 760 TETTVHVTHHRLTRADLDDPRRGSVIGTPLADLRVHLLDDAGRPVPPGATGEMYVSGAGV 819
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
AAGY+ A+RF D+P+ P R+YR+GD G + Y GR DAQ+++RG R
Sbjct: 820 AAGYLDRPDLTADRFLDDPYG--PPGTRMYRSGDLARRRPDGTLDYLGRADAQIQLRGFR 877
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+ E+E LA PGV + V+ D G ++ + A S + + L
Sbjct: 878 VEPGEIEAVLASHPGVTRAAVVARRADNGAQHLVAYTVASGAAPVSPAELRAHTAAHLPE 937
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+M+P V + V+++PL NGK+D + L A D +
Sbjct: 938 HMVPAVCVPVDALPLTANGKLDVRAL--------------PAPDFTAAASGNRPGTPEEA 983
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEISDFLGASTLG 552
+ + + R T+ F++LGG+SL + + +LR D G + I+ T
Sbjct: 984 VVCALFEDVLKLPRETVGTDVNFFDLGGDSLLATRLLARLRHDTGAEIPITALFETPT-P 1042
Query: 553 EVLSKMSTDPNGGA 566
L++ T GGA
Sbjct: 1043 AALARRLTAHTGGA 1056
Score = 52.4 bits (120), Expect = 5e-05
Identities = 86/386 (22%), Positives = 149/386 (38%), Gaps = 35/386 (9%)
Query: 101 PLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSEEICVWKTALTFVD 160
P D + ++L TSGSTG+PK VRL++ + R +T + W L V
Sbjct: 1825 PARPDDLILMLMTSGSTGLPKAVRLTHRNVLTRSAATEQTNRLGADDVSLNW-IPLDHVT 1883
Query: 161 SVC--EIWGPLLHGRALLILSRETTRDPQKLVNI-ERLVLVPTLLRSILMYLALGPASR- 216
V + L R + + +DP + +++ +R + T + L + R
Sbjct: 1884 GVVMFHLRDVYLGCRQIHAPTSWILQDPPRWMDLADRYRVTVTWAPNFAFGLLAEQSDRF 1943
Query: 217 -----PLRRLKLWVCSGETLSKELASEFF---KYFGNEDGYKLANFYGSTEVMGDVTYYV 268
L ++L + +GE + A F K FG +G +E VT V
Sbjct: 1944 ADRDWDLSPMRLVMNAGEVVVASAARRFLRALKPFGLPQDVMHPG-WGMSETCSVVTDAV 2002
Query: 269 LEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGGAN 328
L + + G P A+ ++DE+ + + E G V G ++ GY
Sbjct: 2003 LPAEPRDGEGTFVSCGLPYPGFAMRIVDEQGTVLDEGEAGRFQVRGTSVTGGY------- 2055
Query: 329 RFCDNPHATQPEFQR--LYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQ 386
DNP A F + TGD L G + GR + + G E+E + +
Sbjct: 2056 --HDNPAANAEAFTEDGWFDTGDLAYLSDGELYITGRAKDVIIVNGVNHYSHEIEACVEE 2113
Query: 387 VPGVDKCVVLCYGL--DRGNPE---ILGFVTTKPGARTSAQHIEGKLRSAL---THYMMP 438
+P V+ + D +P L F + + + I GK+ + +++P
Sbjct: 2114 LPWVENSFTAAVAVRTDPSSPTDELALFFHPVQDVTAGALREITGKVAREIGVSPAHLIP 2173
Query: 439 QVIEVESIPLLVNGKVDRQGLLKMYE 464
+ +++P GK+ R L K +E
Sbjct: 2174 --VAPDAVPKTEIGKIQRTKLRKAFE 2197
>UniRef50_Q5YVZ9 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Nocardia farcinica|Rep: Putative non-ribosomal
peptide synthetase - Nocardia farcinica
Length = 6036
Score = 198 bits (482), Expect = 6e-49
Identities = 165/560 (29%), Positives = 250/560 (44%), Gaps = 55/560 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+ A AG AYVP++P P RI ++L A P +V+ + +
Sbjct: 5258 VTAMYAVHAAGGAYVPIDPDLPADRIDYMLATAAPVVVL-----------------TALD 5300
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L + A + DAE LAPL D +A +L+TSGSTG PKGV + + A+ N++ W
Sbjct: 5301 DL--DLAGLDATQVTDAERLAPLRPDHLAYILFTSGSTGRPKGVAIPHRAVVNQVRWLTD 5358
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ ++ + KT TF SV E++G L G L+I DP L + V
Sbjct: 5359 AYALGPG-DVVLQKTPATFDVSVWELFGSLAVGARLVIARPGGHTDPAYLAEVIAAHGVT 5417
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + + S+L A + LR L+ + +GE ++ + + +L N YG
Sbjct: 5418 ITSFVPSMLAAFAQSAPASALRSLRALLVAGEAFGADVVAAVRRVLPE---VELHNLYGP 5474
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T + D +P+G P+ N Y+LD L P GE+++AG +
Sbjct: 5475 TEFTVHATARPVRAGDT----GAVPMGTPVWNARAYVLDARLRPVPPGVVGELYLAGVQV 5530
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY G A RF +P+ +RLYRTGD + G + Y GRTD QVK+RG R
Sbjct: 5531 ARGYHARPGLTAERFVPDPYG---HGERLYRTGDLVRRNRTGDLEYLGRTDFQVKLRGLR 5587
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L EVE LA+ PGV + + ++G++ PGA + + L
Sbjct: 5588 IELGEVEAVLAEHPGVARALAAVRSTGAA-ARLVGYLVPAPGATLDVDAVLAHAAAELPD 5646
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P V+ ++S+PL +GK+DR L + D+
Sbjct: 5647 YMVPGAVVVLDSVPLTPSGKLDRNRLPE--------------PDVAHGAYREPATWLERE 5692
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEISDFLGASTLG 552
VLG G FY LGGNSL S+ +L RD Y V +S FL
Sbjct: 5693 VAEVFEHVLGVERVGA---DDDFYALGGNSLRSVQVAGELSRDLHYEVPVSWFLSDPRPA 5749
Query: 553 EVLSKMSTDPNGGADSKEAT 572
++ ++ T G + E T
Sbjct: 5750 DLAKRIETGMRSGRPAPEPT 5769
Score = 166 bits (404), Expect = 2e-39
Identities = 144/449 (32%), Positives = 214/449 (47%), Gaps = 30/449 (6%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
+ + A+ A KAGAA++P++PS P RI +L D+ +L + D +A ++
Sbjct: 3139 AAVTAVWAVAKAGAAFLPIDPSLPAERIAFLLSDSGAALAVTDSAAAAAVPAAVATLVLD 3198
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E+ + S A DAE P+ D +A ++YTSGSTG PKGV +++ + + + Q
Sbjct: 3199 DEDTRRAVESVPAGRVTDAERGGPVRLDDVAYLIYTSGSTGTPKGVLVTHRGLADLVAAQ 3258
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGR-ALLILSRETTRDPQKLVNIERLV 196
R D + A +F SV E+ L HG A LI++ +L ++ R
Sbjct: 3259 HRLLGV-DRNAAVLQVAAPSFDASVFELL--LAHGAGARLIVAPPQVYGGPQLADLIRGE 3315
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + + LA PA L L++ +GE + EL + G ++ N YG
Sbjct: 3316 HVTHAVVTPSA-LATVPADG-LDELRVLATAGEAVGVELVERW------APGRRMVNLYG 3367
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPI--GRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
+E T + G DL P PI G P+ A +LD L P GE+++ G
Sbjct: 3368 PSES----TIWATAG----DLRPGAPITIGGPVGPVAAVVLDTWLRPAPIGVVGELYLFG 3419
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIR 371
A +AAGY G G A RF P + R+YRTGD + GA+ + GR D QVKIR
Sbjct: 3420 AGVAAGYAGRRGLTAARFVACPF----DGGRMYRTGDLVRRNRDGALEFVGRNDFQVKIR 3475
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G RV+L E++ ALA V V + + G + +V GA S + G L
Sbjct: 3476 GTRVELGEIDAALAAQDAVAFAVTVPRRIGGGAVVPVSYVVPAAGAAVSGTELRGALADE 3535
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P V+ ++ +PL NGK+DR L
Sbjct: 3536 LPAYMVPAAVVVLDEVPLTANGKLDRDAL 3564
Score = 144 bits (350), Expect = 6e-33
Identities = 131/451 (29%), Positives = 210/451 (46%), Gaps = 25/451 (5%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A A K GAAYVP++P +P GRI ++ D+ +L + + +
Sbjct: 4191 SVVAWWAVVKTGAAYVPVDPGYPAGRIEQMVTDSGATLGLTVAAVRDRLPAAVEWVVLDA 4250
Query: 79 EELAQEATSHSADEPM----DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
+ A + + A P DAE L PL + A V++TSGSTG+PKGV ++++ I + L
Sbjct: 4251 DARADDTAARLAALPGGRIGDAERLRPLRPANTAYVVFTSGSTGVPKGVAVTHAGIADFL 4310
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER 194
Q R + + + + +F S+ EI + G A L+++ +L R
Sbjct: 4311 AGQ-RGYGVGPDSRVLHFASP-SFDASLLEIL-LAVGGAAALVIAPTELYGGTELGEFLR 4367
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG--YKLA 252
V + ++ PA L L++ + G+ + +L ++ G +D +
Sbjct: 4368 TQRVTHAFVTPAALASVDPAG--LDDLRVVLSGGDEVPADLVR---RWTGTDDAGVREFR 4422
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE V D+ IG P+ +LD L P GE+++
Sbjct: 4423 VLYGPTEAT-----IVATAVDRGQPTARSCIGTPVPGMRTLVLDARLQPVPVGVAGELYL 4477
Query: 313 AGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVK 369
AG LA GY+ G A RF P+A E R+YRTGD + GA+ + GR D QVK
Sbjct: 4478 AGPGLARGYLDRPGTSAGRFVACPYAGPGE--RMYRTGDLVRWNRAGALEFMGRNDFQVK 4535
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG RV+L E++ AL P V V + G ++ +V + GA + + L
Sbjct: 4536 VRGFRVELGEIDAALTARPDVRYAVTVPRRDGAGPVMLVSYVVPEAGALPAEADLRAALT 4595
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L YM+P V+ ++ IPL NGK+DR+ L
Sbjct: 4596 TVLPSYMVPAAVLILDRIPLSPNGKLDRRAL 4626
Score = 142 bits (343), Expect = 4e-32
Identities = 136/447 (30%), Positives = 207/447 (46%), Gaps = 38/447 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+A+ A GAA+VP++P+ P RI +L DA +L + D+ + S V +
Sbjct: 2095 VAIWAVAMTGAAFVPIDPANPPERIAGLLADAHCALGVTIDAVAHQL--PSTVEWLR--- 2149
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
A E T + P P+ D+ A V+YTSGSTG PK V++S+ + N + Q
Sbjct: 2150 -ADEETVATVPSPA-----GPVLPDTTAYVIYTSGSTGTPKAVQVSHRGLANLVAAQADA 2203
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGR-ALLILSRETTRDPQKLVNIERLVLVP 199
F D+ + + + F V E+ L H R A L ++ +L E L+
Sbjct: 2204 FAV-DTASVVLQVASPGFDACVSELL--LAHSRGACLSIAPPQVYGGSEL---EDLIGRE 2257
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ +I+ LG + P R L + + + ++ + +G G +L N YG TE
Sbjct: 2258 HITHAIITPSVLGTMA-PDRVPSLATVA--VVGEATGADLVRRWGA--GRRLLNHYGPTE 2312
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
T GS +L + IG P+ ++ +LD L P GE++V G LA
Sbjct: 2313 -----TTIWATGSTELRPGDQVTIGAPIPGTSVRVLDAWLRPVPVGVTGELYVGGPGLAR 2367
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGA----VLYAGRTDAQVKIRGH 373
GY G A RF +P +P +R+YRTGD V+G + Y GR D QVKI G
Sbjct: 2368 GYHERPGLTATRFVADPD--RPG-ERIYRTGDAVRWVRGRDGLELAYLGRNDQQVKIHGL 2424
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++ E++ LA+ P V + + G P ++ +V GA + L AL
Sbjct: 2425 RIEPGEIDAHLARRPAVARVATVDQRGPAGEPVLVSYVVPAAGAELDVTALRADLERALA 2484
Query: 434 HYMMPQVIEV-ESIPLLVNGKVDRQGL 459
HYM+P I V + +PL GKVDR+ L
Sbjct: 2485 HYMIPAAIVVLDDLPLTPVGKVDRKAL 2511
Score = 132 bits (319), Expect = 3e-29
Identities = 123/451 (27%), Positives = 202/451 (44%), Gaps = 31/451 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A A + GAA V ++P++P RI H++ D+ V+ A+ GV
Sbjct: 559 SVLAAWAVARCGAAIVQIDPAYPAARIEHMIADSGARTVL--TVAEHRDRVPDGVAALVL 616
Query: 79 EELAQEAT-SHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
++ A A + +AD P+ D E PL A + YTSGSTG PKGV+++++ + +
Sbjct: 617 DDPATRAALAGTADGPVGDDERTRPLRPADTAYLTYTSGSTGTPKGVQVTHAGLAGLIAD 676
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+ + + + + + +F S+ + G AL+++ E + L +
Sbjct: 677 RVAAYGMAADSRVS-YALSPSFDASLEQFLTCFASGAALVVVPPEIIGG-EGLTRLLAQA 734
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V L + M + P PL L+ V G+ + + + L N YG
Sbjct: 735 RVTHLTLTPAMLATVDP--EPLTELRAVVVGGDVCPPNVVERW------TGPWALLNEYG 786
Query: 257 STEVMGDVTYYVLE-GSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE L G D+ +G P+ A +LD L P PGE+++AG
Sbjct: 787 PTEATVTAACARLRPGHDRT-------VGGPIRGVAAMVLDRTLQPVPPGTPGELYLAGP 839
Query: 316 NLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL----VKGAVLYAGRTDAQVK 369
LA GY G A RF +P+ E R+YRTGD + + GR+D QVK
Sbjct: 840 GLARGYRHRVGETAARFVADPYGAPGE--RMYRTGDLARWRTDSAEPELELLGRSDFQVK 897
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG+R++ E++ AL V+ V + G + +V G R ++ R
Sbjct: 898 IRGYRIEPGEIDAALTGHEHVELSVTVPVPNKSGTTVLASYVVPVRGHRLDVAELQRFAR 957
Query: 430 SALTHYMMPQVI-EVESIPLLVNGKVDRQGL 459
+ L +M+P V+ +ES+P+ GKVDR+ L
Sbjct: 958 ATLPPHMVPTVLMPLESLPVNAFGKVDRRAL 988
>UniRef50_Q3M5N4 Cluster: Amino acid adenylation; n=1; Anabaena
variabilis ATCC 29413|Rep: Amino acid adenylation -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 1345
Score = 198 bits (482), Expect = 6e-49
Identities = 140/447 (31%), Positives = 225/447 (50%), Gaps = 22/447 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAE-PSLVIYDDSADPSMFKESGVPFASF 78
++ +L KAG AY+P +P++PQ R+ +L+DA+ P L+ D F E
Sbjct: 533 LIGILGILKAGGAYIPFDPTYPQERLGFMLEDAQIPILLTQQRLVDK--FVEHKTQIICL 590
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ E + S D P+ + +TS+++A ++YTSGSTG PKG + + + N L W
Sbjct: 591 DRDLPENATLSIDNPV-----SNVTSENLAYIIYTSGSTGKPKGTMIPHRGLVNYLSWCT 645
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK--LVNIERLV 196
+ + V ++++ F ++ ++ PLL G+ +++L + + L + +
Sbjct: 646 NAYALAQGYGAPV-QSSIGFDATITSLFSPLLVGKRVVLLPEKEEIEALSALLQSDQNYS 704
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
LV + M + P + + + + GE L L + N ++ N YG
Sbjct: 705 LVKITPAHLEMLNQMLPNHKGVTETRALIIGGEAL---LGKSLNFWRDNAPKTRIINEYG 761
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE + V V E +Q L I IGRP+ N +YLLD++ PGE+++ GA
Sbjct: 762 PTETV--VGCCVYEVDEQTSLSGAILIGRPIANTQLYLLDDKQKLVPIGVPGELYIGGAG 819
Query: 317 LAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ RF NP + +P RLY+TGD L G + Y GR D QVKIRG
Sbjct: 820 VARGYLNRPELTQQRFIPNPFSDEPN-SRLYKTGDLARYLPDGNIEYLGRIDHQVKIRGF 878
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E LAQ P V+ V+ G+ ++G++ K A TS++ + L+S L
Sbjct: 879 RIELEEIESLLAQHPLVNAVTVIAREDQPGDKRLVGYIVPKEQAPTSSE-LRQFLQSKLP 937
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + +E IPL +GKVDRQ L
Sbjct: 938 EYMIPSAFVMLEVIPLTTHGKVDRQAL 964
>UniRef50_Q6WZB2 Cluster: Nonribosomal peptide synthetase; n=1;
Streptomyces vinaceus|Rep: Nonribosomal peptide
synthetase - Streptomyces vinaceus
Length = 2123
Score = 198 bits (482), Expect = 6e-49
Identities = 150/460 (32%), Positives = 226/460 (49%), Gaps = 30/460 (6%)
Query: 22 ALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEEL 81
A+ KAG YVP+EP P RI +++D+ +++ S+ K GV ++
Sbjct: 1157 AVYGVLKAGGGYVPIEPDNPPERIAGLVRDSGARVLLTQRRQTASLPKLPGVTVLVVDD- 1215
Query: 82 AQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTF 141
EA S P P D +A V+YTSGSTG PKGV + + ++ N L F
Sbjct: 1216 -HEALSRF---PATVPKPVPRPQD-LAYVIYTSGSTGRPKGVMVEHHSVVNYLTTLQEKF 1270
Query: 142 PYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER-----L 195
+ + + + K+ L+F SV E++ L G L++ DP LV IER +
Sbjct: 1271 RLTSDDRLLL-KSPLSFDVSVREVFWALSTGATLVVAEAGRHADPDYLVEAIERERVTVV 1329
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
VP++L +L L GP P L+ + SGETL + A + G E L N Y
Sbjct: 1330 HFVPSMLHVLLETLD-GPGRCPT--LRQVMTSGETLPVQTARRCLELLGAE----LRNMY 1382
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE ++T + G + +PIGRP N +Y+LD+EL GE++V+GA
Sbjct: 1383 GPTETTVEMTDCEVRGRTDTE---RLPIGRPFPNTRVYVLDDELRLVPRGTVGELYVSGA 1439
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRG 372
+A GY+G A+RF +P+ P R+YRTGD G +G + + GR D QV++RG
Sbjct: 1440 PVARGYLGRPALTADRFLPDPYG--PPGSRMYRTGDLGRFTGEGLLDFQGRGDFQVQLRG 1497
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGN-PEILGFVTTKPGARTSAQHIEGKLRSA 431
HR++ E+E L + PGV V + D ++ + + Q + KL
Sbjct: 1498 HRIEPGEIETVLCEQPGVTAAVAVVRRPDSPEAAHLVAYAVRAEEPHGTDQALRAKLAER 1557
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNND 470
L HYM+P V+ ++++PL VNGK+DR L +E D
Sbjct: 1558 LPHYMVPTAVVTMDALPLTVNGKLDRAALPDPWEARATGD 1597
Score = 183 bits (445), Expect = 2e-44
Identities = 151/524 (28%), Positives = 242/524 (46%), Gaps = 36/524 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDA-EPSLVIYDDSAD--PSMFKESGVPFA 76
++ALL KAG A+VP++P++P RI H+L D+ ++++ + D P ++ A
Sbjct: 93 VVALLGVLKAGGAFVPVDPTYPAARIRHMLDDSGARAVLLRQELRDRLPEDLRDGTGQVA 152
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
A+ S P+ P + +A ++YTSGSTG+PKGV + + I + L
Sbjct: 153 VVPVGAESGAGTSTRRPVTPVEQEP-RPERLAYIVYTSGSTGLPKGVMVEHRGIVSYLLG 211
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ER 194
FP + + + T+L+F SV EI+ PLL G A ++ + D L + E
Sbjct: 212 MLEHFPMGPRDRM-LQVTSLSFDVSVYEIFLPLLTGGATVLPRSGSHTDAAYLSGLIAEH 270
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
V ++ S+L G R L+ SGE L L + + + N
Sbjct: 271 GVTSFHMVPSLLRTFVDGLDPRQCAGLRRIFVSGEALDTTLVVDVHDRLPCD----VVNL 326
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG+TEV D T++ L P + +GRP+ Y+LD+E+ +E GEV++ G
Sbjct: 327 YGATEVSVDSTWWT--APRDLPDAPVL-VGRPMAGATAYVLDDEMRRLAPNEVGEVYLGG 383
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIR 371
A++ GY G A RF +P+ P RLYRTGD G + G + GR D QVK+
Sbjct: 384 ASVTRGYHGRAALTAQRFLPDPYG--PPGSRLYRTGDLGRVEDNGELRLLGRIDHQVKLH 441
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++ E+E A+ P V + G G + GF T GA A+ + G L
Sbjct: 442 GRRIEPGEIEAAMTAHPHVSLAAAVPAGAGAG-ATLTGFFT---GAEADAEELRGFLAQR 497
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L ++P +++ ++++PL NGK+DR L A++A D +
Sbjct: 498 LPAALVPSRLVALDTLPLSPNGKIDRNAL------------ADIAARQDLAAVPPAPEHT 545
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR 534
+ A ++ F++ GGNSL++ + KLR
Sbjct: 546 DPVLRAVLDATADVLGGTPVAPHENFFDKGGNSLHATRLVAKLR 589
>UniRef50_Q3WHQ1 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=2; Frankia sp. EAN1pec|Rep: Non-ribosomal
peptide synthase:Amino acid adenylation - Frankia sp.
EAN1pec
Length = 4554
Score = 198 bits (482), Expect = 6e-49
Identities = 152/459 (33%), Positives = 225/459 (49%), Gaps = 33/459 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDS---ADPSMFKESGVPFA 76
+ +L A +AGAAYVP++P +P RI IL+D+ + I D + A + +GV
Sbjct: 545 VTSLAAVLRAGAAYVPVDPGYPAERIAAILQDSGARVAITDSATAVAHAGVLTAAGVVTV 604
Query: 77 SFEELAQEAT-SHSADEPMDAETLA-PLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
+E A H A DA L PLT D A V++TSG+TG PKG+ LS++A+ NRL
Sbjct: 605 VLDEDAVRGQIEHGAP---DAPVLPRPLTPDDTAYVIFTSGTTGRPKGIALSHAAVVNRL 661
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER 194
W +S S+ + + KT TF SV E + PL+ G +++ DP + + R
Sbjct: 662 VWGREALGFSSSDRVLL-KTPFTFDVSVPEFFLPLITGAVVVVARDNAHGDPGYIAGVVR 720
Query: 195 ------LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG 248
+ VP++L++ +L G + ++L +GE L A + F D
Sbjct: 721 KRRVTSVHFVPSMLQA---FLDSGVEAGFFPDVRLVSFTGEALPVAAAIRAREVF---DR 774
Query: 249 YKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPG 308
+L N YG TE ++ Y + + D T PIGRP+ N + +LD L P G
Sbjct: 775 AELFNLYGPTEAAVEIASYDIAALN-ADADST-PIGRPVSNSYVRVLDGWLRPVPVGVTG 832
Query: 309 EVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTD 365
E+++ G LA GYVG G A RF +P E RLYRTGD +G + Y GR+D
Sbjct: 833 ELYLGGVQLAEGYVGRAGLTAERFVADPLGAPDE--RLYRTGDLARWNDQGELEYLGRSD 890
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
QVK+RG R++L E+ L + P V V G + +VTT P A +
Sbjct: 891 DQVKVRGFRIELDEIRAVLERHPAVSGAAVTALDHPAGGKFLAAYVTTTPSAPADQAVLA 950
Query: 426 GKLR----SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
LR + L YM+P + ++P +GK+DR+ L
Sbjct: 951 DALREHTNALLPEYMVPASFTRLATLPTTPSGKLDRKAL 989
Score = 155 bits (376), Expect = 4e-36
Identities = 159/585 (27%), Positives = 257/585 (43%), Gaps = 52/585 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A + GAAYVP++ P RI ++L A P++ + D + +G +
Sbjct: 3512 VIAMFAVFAVGAAYVPIDAELPDDRIGYMLDVAGPTVTLVTDRDVARLGPAAGRVVNLDD 3571
Query: 80 ELAQEATSHSADEPMD-AETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + + AD P+ AE ++ D +A +++TSGSTG PKGV + Y + N
Sbjct: 3572 AVVRARVAELADGPVTVAERGGEVSLDHLAYIIFTSGSTGRPKGVAVGYRGLTNMYANHV 3631
Query: 139 -----RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV--- 190
R + + + T D+ E LL+G ++ +++ E RDPQ+L+
Sbjct: 3632 EKIFDRVVAHQGGRRMRIAHTTSFSFDASWEQLFWLLNGHSVYVINEEMRRDPQQLLAYY 3691
Query: 191 ---NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGE---TLSKELASE-FFKYF 243
I+ + P+ +L+ L RP R +G +L E E ++
Sbjct: 3692 DDQRIDGFDVTPSY-GQVLVDEGLLERDRPAGRSVSADATGVVFVSLGGEAVPERLWQQL 3750
Query: 244 GNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTR 303
+ G + N YG TE T L G+D D P +G P+ N Y+LD+ L
Sbjct: 3751 RDAPGVESYNLYGPTEY----TINAL-GADLADS-PNPSVGTPIFNTRAYILDQNLQFAL 3804
Query: 304 DSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLY 360
PGE+++AGA A GY A RF P +P R+YRTGD +G + Y
Sbjct: 3805 PGVPGELYLAGAGNARGYWEQPALTAERFVACPW--EPG-ARMYRTGDLARWNDEGRIDY 3861
Query: 361 AGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS 420
GR D Q KIRG+R++ E+ L P V + V+ G + +VTT TS
Sbjct: 3862 LGRADEQTKIRGYRIEPGEIRDVLEAHPEVVRAEVIAADHPSGGKFLAAYVTT-ARIDTS 3920
Query: 421 AQHIEGKLRS-ALTH---YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVA 475
+ LR A H YM+P +E+ PL GK+DR+ L + A
Sbjct: 3921 DDALRRSLREHAAQHLPDYMIPASYNRLETFPLTTTGKLDRKALPVPDLGQSTAHGRAPA 3980
Query: 476 VDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
D + + +LG + LS+ F++LGG+S+ SI ++++R
Sbjct: 3981 TDTE------------QDLLAAIRDLLGLSDEVRLSVEDDFFQLGGDSILSIQLVSRMRR 4028
Query: 536 RGYYVEISDFLGASTLGEVLSKMSTDPNGGADSKEATFTAVPMRD 580
G + +D T+ L+++S S+ AT P++D
Sbjct: 4029 MGVVISAADVFSTRTVAG-LARLS----DARQSESATEHTAPLKD 4068
Score = 143 bits (347), Expect = 1e-32
Identities = 136/464 (29%), Positives = 211/464 (45%), Gaps = 35/464 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A + GAAYVP++ P RI ++L A P++ + D + +G +
Sbjct: 2421 VIAMFAVFAVGAAYVPIDAELPDDRIGYMLDVAGPTVTLVTDRDVARLGPAAGRVVNLDD 2480
Query: 80 ELAQEATSHSADEPMD-AETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + + AD P+ AE ++ D +A +++TSGSTG PKGV + Y + N
Sbjct: 2481 AVVRARVAELADGPVTVAERGGEVSLDHLAYIIFTSGSTGRPKGVAVGYRGLTNMYANHV 2540
Query: 139 -----RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV--- 190
R + + + T D+ E LL+G ++ +++ E RDPQ+L+
Sbjct: 2541 EKIFDRVVAHQGGRRMRIAHTTSFSFDASWEQLFWLLNGHSVYVINEEMRRDPQQLLAYY 2600
Query: 191 ---NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGE---TLSKELASE-FFKYF 243
I+ + P+ +L+ L RP R +G +L E E ++
Sbjct: 2601 DDQRIDGFDVTPSY-GQVLVDEGLLERDRPAGRSVSADATGVVFVSLGGEAVPERLWQQL 2659
Query: 244 GNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTR 303
+ G + N YG TE T L G+D D P +G P+ N Y+LD+ L
Sbjct: 2660 RDAPGVESYNLYGPTEY----TINAL-GADLADS-PNPSVGTPIFNTRAYILDQNLQFAL 2713
Query: 304 DSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLY 360
PGE+++AGA A GY A RF P +P R+YRTGD +G + Y
Sbjct: 2714 PGVPGELYLAGAGNARGYWEQPALTAERFVACPW--EPG-ARMYRTGDLARWNDEGRIDY 2770
Query: 361 AGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS 420
GR D Q KIRG+R++ E+ L P V + V+ G + +VTT TS
Sbjct: 2771 LGRADEQTKIRGYRIEPGEIRDVLEAHPEVVRAEVIAADHPSGGKFLAAYVTT-ARIDTS 2829
Query: 421 AQHIEGKLRS-ALTH---YMMPQVI-EVESIPLLVNGKVDRQGL 459
+ LR A H YM+P I ++S VNGK+DR+ L
Sbjct: 2830 DDALRRSLREHAAQHLPDYMIPTTITRIDSFATTVNGKLDRKAL 2873
>UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2;
Cyanobacteria|Rep: Amino acid adenylation - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 2791
Score = 197 bits (481), Expect = 8e-49
Identities = 125/382 (32%), Positives = 200/382 (52%), Gaps = 20/382 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++LA KAG AY+P++PS+P+ R+ +L+DA+ ++++ + PS+ E +
Sbjct: 1214 VVSILAILKAGGAYLPLDPSYPRERLAFMLQDAQVAVLLTQEKFLPSL-PEHQATVVCLD 1272
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S + P++ +T+ ++A V+YTSGSTG PKGV ++ ICNRL W
Sbjct: 1273 KDNEVWASETIVNPVNE-----VTTHNLAYVIYTSGSTGRPKGVMNTHRGICNRLAWMQE 1327
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
T+ + + + + KT +F S+ E + PL G L++ +D LV + E+ +
Sbjct: 1328 TYQLTIVDRV-LQKTPFSFDVSIWEFFWPLTTGACLVMARPGGHQDSAYLVKLIQEQQIT 1386
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L P+ + L+ +CSGE L +L FF E L N YG
Sbjct: 1387 TIHFVPSMLQVFLAEPSVEACKCLRRVICSGEILPVQLQEHFFTRLDAE----LHNLYGP 1442
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE DVT++ ++ +PIGR + N IY+LD+ L P PGE+ + G +
Sbjct: 1443 TEAAIDVTFWACNRHSDKNI---VPIGRAIANTQIYILDKHLQPVPIGVPGELHIGGVGV 1499
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+ A +F NP + RLY+TGD G++ Y GR D QVK+RG R
Sbjct: 1500 ARGYLNQPQLTAEKFIVNPFSNNSN-NRLYKTGDLARYHTDGSIEYLGRLDDQVKLRGFR 1558
Query: 375 VDLLEVERALAQVPGVDKCVVL 396
++L E+E L Q P V K VV+
Sbjct: 1559 IELTEIESVLTQHPDVRKAVVV 1580
Score = 193 bits (470), Expect = 2e-47
Identities = 135/461 (29%), Positives = 227/461 (49%), Gaps = 28/461 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +L KAG AY+P++P++P + ILKD + SL++ P +
Sbjct: 2320 IVGILGILKAGGAYLPLDPTYPSEHLAFILKDTQVSLLLTQSQLLPKIPNNKAQTLCLDS 2379
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + ++++D+ T T +++A V+YTSGSTG PKGV +++ + + +
Sbjct: 2380 EW--DIIANNSDDNPSCRT----TKENLAYVIYTSGSTGNPKGVLITHQNLVHSTNARIA 2433
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
+ S + + + F SV I+ L G L+++ RD +L I
Sbjct: 2434 YYQTPISSFLLI--PSFAFDSSVAVIFWTLCQGGKLILIKDGWQRDIWQLAQLIEQHQIT 2491
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP+L S+L ++ + L L+ + +GET S EL K N L N
Sbjct: 2492 HWLSVPSLYNSLLAHIE----KQQLISLQTIIVAGETCSIELVKNHQKLLPNTS---LFN 2544
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + Y D + +IPIGRP+ N IY+L+ L P PGE+++
Sbjct: 2545 EYGPTETTVWSSVYNCSHHDLNN--NSIPIGRPISNTQIYILNSHLQPVPIGTPGEIYIG 2602
Query: 314 GANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G ++ GY+ +F +P + QP RLY+TGD L G + + GR D Q+K+
Sbjct: 2603 GFGVSKGYLNRPELTIEKFIPDPFSKQPN-ARLYKTGDQARYLSNGNIEFIGRIDHQIKL 2661
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG+R++L E+E L Q P V + +V+ D N +++ ++ + + L++
Sbjct: 2662 RGYRIELGEIEAVLQQHPQVKQAIVIARNSDSENQQLVAYIVPSQTQDSLTNELRSFLQT 2721
Query: 431 ALTHYMMPQVI-EVESIPLLVNGKVDRQGLLKMYENTNNND 470
L +YM+P VI +++++PL NGK+DRQ L + NN+
Sbjct: 2722 KLPNYMIPSVILQIDTLPLTPNGKIDRQKLPTPEQLQPNNE 2762
Score = 52.4 bits (120), Expect = 5e-05
Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 284 GRPLDNCAIYLLDEE-LSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQ 342
G+PL + I ++D + LS D + GE+WVAGA++A GY + +
Sbjct: 377 GQPLADLKIVIVDPQTLSACSDRQVGEIWVAGASVAQGYWHQPEQTESTFKAYTKDTKEG 436
Query: 343 RLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQ 386
RTGD G L G + GR + IRG ++E + Q
Sbjct: 437 PFLRTGDLGFLQDGELFITGRLKDLIIIRGRNYYPQDIENTVQQ 480
Score = 38.3 bits (85), Expect = 0.78
Identities = 44/192 (22%), Positives = 81/192 (42%), Gaps = 24/192 (12%)
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L L YM+P I ++++P+ NGK+D++ L + N + + V
Sbjct: 1647 LGEKLPDYMIPATFIMLDALPVTANGKLDKKSLPNPGQGRPNLEKSFVPPH--------- 1697
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
VLG G + F+ELGG+S+ SI + K ++RG ++
Sbjct: 1698 -TLHEKILAQIWSEVLGIEQVG---IHDNFFELGGDSIRSIQVVAKAQERGLSFSVAQVF 1753
Query: 547 GASTLGEVLSKMSTDP-NGGADSKEATFTAVPM--RDEHKKEVID-----MVESS--FYE 596
T+ +L+ +S + + K A F+ + RD+ + D V++ F+
Sbjct: 1754 QHQTIYNLLTAISLNQLDSLLTEKTAAFSLISAIERDKLPNNIEDAYPLTRVQTGIIFHS 1813
Query: 597 KAELEQFLKHEI 608
+ LE + H+I
Sbjct: 1814 QYNLESLMYHDI 1825
Score = 34.7 bits (76), Expect = 9.7
Identities = 14/23 (60%), Positives = 19/23 (82%)
Query: 105 DSIAIVLYTSGSTGIPKGVRLSY 127
D++A + YTSGSTG PKGV +S+
Sbjct: 167 DTLAFLQYTSGSTGTPKGVMVSH 189
>UniRef50_Q1DBW4 Cluster: Non-ribosomal peptide synthetase; n=3;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Myxococcus xanthus (strain DK 1622)
Length = 5544
Score = 197 bits (481), Expect = 8e-49
Identities = 158/550 (28%), Positives = 255/550 (46%), Gaps = 34/550 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+L KAG AYVPM+ S P R++ +L+D +++ +D+ ++ +
Sbjct: 3682 VVAVLGVLKAGGAYVPMDASQPPARLSFLLEDTGTPVLVTEDAVADTLPVSQALVLCLDS 3741
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + A S D P+++ + A + +A ++YTSGSTG PKGV + + + N L W +
Sbjct: 3742 EWERTAGRES-DAPLESVSSA----EDLAYLIYTSGSTGRPKGVLVEHRGVVNYLHWARK 3796
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRD--PQKLVNIERLVL 197
+ D V ++L F +V + PL GR + ++ E + L L
Sbjct: 3797 AYAVDDGAGAPV-HSSLAFDLTVTSLLLPLTAGRPVTLVPEEDGVEGLATALRTSADFSL 3855
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + M A P + +V GE L+ + ++ + +L N YG
Sbjct: 3856 VKLTPAHLQMLAAQLPPEARAGHTRAFVIGGEALTSATVEPWRQHAPST---RLINEYGP 3912
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + + +E ++ +PIGRP+ N +Y+LD L P PGE+++ G +
Sbjct: 3913 TETVVGCCVHTVEADTPVE--GAVPIGRPIANTRLYVLDAALRPVPAGVPGELYIGGEGV 3970
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHR 374
A GY A RF +P ++ P R+YRTGD L VL Y GR D QVK+RGHR
Sbjct: 3971 ARGYWRRPELTAERFVPDPFSSVPG-ARMYRTGDRVRLRPSDVLEYLGRVDFQVKVRGHR 4029
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+ EVE AL ++PGV VV+ P ++G+VT A + + L L
Sbjct: 4030 VEPGEVEAALIELPGVASAVVVLREDGTTGPRLVGYVTGH-DAMPETEPLRASLAQRLPA 4088
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+M+P ++ + +PL NGKVDR+ L +A A D D
Sbjct: 4089 HMVPSALVALAQLPLTANGKVDREAL--------PAPEAPAASDED---FVSPSTPTEHA 4137
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
+LG G R F+ELGG+SL S+ +++R+R G + ++ TL
Sbjct: 4138 LAQLWEELLGVQRVGA---RDDFFELGGHSLLSVQLASRVRERLGVELPVATLFATPTLA 4194
Query: 553 EVLSKMSTDP 562
+ +++ P
Sbjct: 4195 ALAARIDASP 4204
Score = 183 bits (445), Expect = 2e-44
Identities = 134/450 (29%), Positives = 209/450 (46%), Gaps = 21/450 (4%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKE-SGVPFA 76
+T+ ALL+ KAGAAY+P++ P R+ +L ++ V+ + + + + +P
Sbjct: 1577 ATVRALLSLHKAGAAYLPLDAQLPAARLARLLMESRAPFVLPLGPIEALLTEVLAEIPL- 1635
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
E + + + + DA T DS+A VL+TSGSTG PKGV + + + N L
Sbjct: 1636 --EHRPRVLSLQNLEAESDAPLPPFTTPDSLAYVLFTSGSTGTPKGVMVDHRGMLNHLLG 1693
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+ S+ + L+F S+ ++ G L G ++ + R+P +L+ +
Sbjct: 1694 MQHSLQLGASD-VLAQTAPLSFDISIWQMLGALAAGGTTYVVDDDVVREPARLIAALQQA 1752
Query: 197 LVPT--LLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
T L+ S+L L P PL L+ + GE L +F+ G L N
Sbjct: 1753 GATTVELVPSLLQALLEEPGEAPLPALRQMLTIGEALPPSTCRAWFE---RHPGLPLVNA 1809
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG E T + + + PIG P N +Y+LD+ L P PGE+++ G
Sbjct: 1810 YGPAECADTATLWRMHAPPAS---ASTPIGTPKANLEVYVLDDALQPLPPGVPGELYIGG 1866
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
+ GYVG A RF +P +T P RLYRTGD G G + + GR D QVK+R
Sbjct: 1867 TGVGRGYVGRADLTAERFIPHPFSTMPG-ARLYRTGDRGRWNADGTLGFLGRVDFQVKVR 1925
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L EVE ALA +PGV V + + +V T ++ L
Sbjct: 1926 GMRIELGEVEAALASLPGVRSAAVTVQRRGPSDSWLAAWV-VPASPDTDVHSLQAALARL 1984
Query: 432 LTHYMMPQ--VIEVESIPLLVNGKVDRQGL 459
L +M+P V+ + +PL GK+DR+ L
Sbjct: 1985 LPAFMLPSRWVLRAQ-LPLTSTGKLDRKAL 2013
Score = 174 bits (423), Expect = 9e-42
Identities = 134/446 (30%), Positives = 208/446 (46%), Gaps = 22/446 (4%)
Query: 22 ALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEEL 81
ALL KAG +YVP++ +P+ R +L + + D A + +G+ E
Sbjct: 4742 ALLGILKAGGSYVPLDAGWPEPRKRSVLTRSGVQRLWVDAEA---LEAHAGL-VPDVEVP 4797
Query: 82 AQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTF 141
Q A EP A +A +++TSGSTG PKGV + + ++ N F
Sbjct: 4798 PQPAHIAEDLEPGPRHVAA----SQVAYIVFTSGSTGEPKGVMVEHRSVVNHNVALAARF 4853
Query: 142 PYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILS----RETTRDPQKLVNIERLVL 197
+ + + L+F + +++ PL+ G +++ S + +I + L
Sbjct: 4854 GLRPGDRMLQF-APLSFDAAAEDLYPPLVVGATVVMRSGLVPAHVMTPYLEETDITLISL 4912
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
PT + + + R RL+L G+ L +E + + G + N YG
Sbjct: 4913 PPTYIEEWIRQME-SHGQRVPARLRLLAPGGDVLKRETYEAWVRVGGGHAPW--LNVYGP 4969
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + G++ L T PIGRP+ I+LLDE L P PG V++ GA
Sbjct: 4970 TECTITSATCDIPGAEGLGTDATFPIGRPISRVRIHLLDEHLEPVLPGLPGRVYIGGAAP 5029
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY+G A RF +P AT+P R+Y TGD ++ G + + GR D Q+KIRG R
Sbjct: 5030 ARGYLGAPDMTAERFIPDPFATEPG-ARMYHTGDLARMLPDGRLRFLGRADHQIKIRGFR 5088
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+L E+E L Q PGV++ VVL G ++ F+ P A + + + L
Sbjct: 5089 VELAEIEACLRQFPGVEEAVVLARAGGSGQTQLQAFLQAPP-QHVRADALREHVAARLPS 5147
Query: 435 YMMPQVIEV-ESIPLLVNGKVDRQGL 459
YM+P + V E++P+ NGKVDRQ L
Sbjct: 5148 YMVPAALVVLEALPINANGKVDRQAL 5173
Score = 173 bits (421), Expect = 2e-41
Identities = 136/454 (29%), Positives = 217/454 (47%), Gaps = 28/454 (6%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKE--SGVPF 75
+T+ AL++ KAG AY+P++ P R+ +L+++ V+ D+ D ++ E +GVP
Sbjct: 516 ATVRALMSIHKAGGAYLPLDAQLPAARLARLLEESRAPFVLPLDT-DEALLSEVLAGVP- 573
Query: 76 ASFEELAQEATSHSADEPMDAETLAP-LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
E S E AE L P T DS+A VL+TSGSTG PKGV + + + N L
Sbjct: 574 ---EARRPRVLSLEGLESQSAERLPPRATPDSLAYVLFTSGSTGTPKGVMVDHRGMLNHL 630
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-- 192
D ++ AL+F S+ ++ G L G ++ + RDP +L +
Sbjct: 631 LGMREALGL-DGYDVVAQIAALSFDISIWQMLGALPGGGTTYLIEDDVMRDPPRLADALE 689
Query: 193 ERLVLVPTLLRSILMYLALGPA-SRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ V ++ S+L + G + ++ V GE + L + + G ++
Sbjct: 690 QGRATVMEMVPSVLQAILEGARPEQDFPDMRWVVLGGEPVPPALCRTWLERC---PGCRM 746
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
A+ YG TE + + + + PIG P N +Y+LD+ L P GE++
Sbjct: 747 ADAYGPTESSDVASLHFINEPPEGSF---TPIGTPKANMEVYVLDDALQPVPVGIVGELY 803
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
+ G +A GYVG A RF +P + P RLYR+GD G L G + + R D QV
Sbjct: 804 LGGLGVARGYVGRADLTAERFVPHPFSATPG-ARLYRSGDLGRWLPDGVLQFVSRADLQV 862
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQH-IEGK 427
K+RG R++L EVE ALA +PGV V + + +V P + + H ++
Sbjct: 863 KVRGMRIELGEVEAALASLPGVRSAAVTVQRRGPSDSWLAAWVV--PASPDADVHSLQAA 920
Query: 428 LRSALTHYMMPQ--VIEVESIPLLVNGKVDRQGL 459
L L +M+P V+ + +PL GK+DR+ L
Sbjct: 921 LARLLPAFMLPSRWVLRAQ-LPLTSTGKLDRKAL 953
Score = 135 bits (327), Expect = 4e-30
Identities = 134/448 (29%), Positives = 208/448 (46%), Gaps = 40/448 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFK--ESGVPFAS 77
+++L+A + +GA +P+E S P R +L+ A LV+ + P +F E GVP S
Sbjct: 2642 VVSLVAIFISGAGCLPLEASHPPARRAALLRQARARLVV----SRPGLFAGVEPGVPLVS 2697
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ + P AE LA L LYTSGSTG PKGV L++ + + +
Sbjct: 2698 PDVRGDVV---AVPRPPRAEHLAYL--------LYTSGSTGEPKGVELTHRNVVH-CFAA 2745
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV--NIERL 195
F T+ + + +L+F + E+ + G ++ + ++ I +
Sbjct: 2746 FDTYYATQPGDCWASSGSLSFDIHLEELLFSITRGARTVLREVGPLGLGRDILGHGITHV 2805
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
V+ P+ S+ L A+ R LK+ V GE L L + +L N Y
Sbjct: 2806 VITPS---SLATALEEPRAAEAFRSLKVLVTGGEVLPDPLVRQLAL-----THTRLVNTY 2857
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE +V + L P + +GRPLD C +Y+LD +P PGE+++ G
Sbjct: 2858 GPTETSINVAAEI-----TLPDRP-VRLGRPLDRCRLYVLDANGAPVPPGVPGELYIGGT 2911
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRG 372
L GY A RF + + + E RLYRTGD G++ + GRTD QVK+RG
Sbjct: 2912 CLGRGYRDRPDLTAERFIPDAFSGR-EGGRLYRTGDRVRWNGDGSLGFLGRTDFQVKVRG 2970
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
RV+L EVE AL + PGV + V+ G R + + F+ + A + L AL
Sbjct: 2971 VRVELEEVEAALLRQPGVRQASVVVRGTQR-DARLEAFLVLEGTAAGVESRLREGLSRAL 3029
Query: 433 THYMMPQVIEV-ESIPLLVNGKVDRQGL 459
++P V ++P+ +GKVDR+ L
Sbjct: 3030 PEALVPSRFTVLTALPMTTSGKVDRKAL 3057
>UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 3176
Score = 197 bits (481), Expect = 8e-49
Identities = 145/451 (32%), Positives = 223/451 (49%), Gaps = 34/451 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPS-LVIYDDSADPSMFKESGVPFASF 78
++ALLA KAG AYVP++P +P R+ ++ A+ L+ D ++ V
Sbjct: 1360 VVALLAILKAGGAYVPVDPEYPAERVRFMIDHAQLRWLLTQQHLLDALPDTDARVIVVDR 1419
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ L +A S P L+ +++A ++YTSGSTG PKG ++ AI NR+ W
Sbjct: 1420 DTLDLDAAPASNPAPA-------LSGENLAYMIYTSGSTGRPKGALNTHRAITNRILWMQ 1472
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERL 195
+ +++ + KT +F SV E + PL+ G L+ R+ LV + ER+
Sbjct: 1473 HAYMLG-ADDAVLQKTPFSFDVSVWEFFWPLIAGARLVFARPGGQRETDYLVELIERERI 1531
Query: 196 V---LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
VP++LR+ L + L LRR+ VCSGE L +L +L
Sbjct: 1532 TTVHFVPSMLRAFLDHPDLDAHCTSLRRV---VCSGEALPYDLQQRCLARLD----VRLF 1584
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE DVT + D + +PIGRP+ N +Y++D +L P GE+ +
Sbjct: 1585 NLYGPTEAAVDVTAWECRRDDP---HRIVPIGRPIANTRVYIVDAQLQPVPVGVAGELLI 1641
Query: 313 AGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
G + GY G A +F +P + + RLYRTGD G + + GR D Q+K
Sbjct: 1642 GGTPVGRGYHGEPELSAEKFIADPFSADSQ-ARLYRTGDLARYRPDGNIEFLGRIDHQIK 1700
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG R++ E+E AL + P VD CVV+ D ++ +V T A + G L
Sbjct: 1701 LRGLRIEPGEIEAALREHPSVDDCVVIA-KTDGARTFLIAYVAT---ASPDLADLRGYLS 1756
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P + + +ES+PLL NGK++R+ L
Sbjct: 1757 GKLADYMVPSKFVTLESLPLLPNGKINRKAL 1787
Score = 175 bits (426), Expect = 4e-42
Identities = 144/453 (31%), Positives = 218/453 (48%), Gaps = 36/453 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+L KAGAA+VP++P++P RI HIL D SL++ S ++ SGV +
Sbjct: 317 IVAILGILKAGAAFVPLDPAYPAERINHILGDTGLSLLVTQSSQLAQWYEFSGVTLLLDQ 376
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL T + P AE ++A V+YTSGSTG PKG L + + + + W
Sbjct: 377 EL-PGWTPLPDNPPCRAEPA------NLAYVIYTSGSTGRPKGCLLEHRNLAHYIAWAAG 429
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP------QKLVNIE 193
+ + ++L F ++ I+ PL+ G++L I + + D Q ++
Sbjct: 430 YYFADSTTGSFGLYSSLCFDFTLTNIFCPLVRGKSLRIYPQSESIDTILARMFQPGSGVD 489
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L L PT + +L Y+ L + +R++ + GE L+ + + K + + N
Sbjct: 490 TLKLTPTHIH-LLEYMNLSRSG--VRKV---IVGGEELTPQHIATLRKI---DPALDIYN 540
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE ++G+ PT+ IGRP+ N +Y+LD+ L P PGE+ +A
Sbjct: 541 EYGPTEATVGCIVERVDGTP-----PTVLIGRPIANTRVYMLDDALRPVPLGVPGEICIA 595
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY A +F ++P P R+YRTGD G L G + GR D QVKI
Sbjct: 596 GDGLARGYHQRPDVTAAKFVEHPF---PGEARIYRTGDIGRWLPDGQIQCYGRVDDQVKI 652
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RGHRV+L E+E AL V V+ G ++ +V K A + + L
Sbjct: 653 RGHRVELGEIEAALTAHEDVVGAAVMLRESAHGVRKLAAYV--KGSANLNVADLRAFLAG 710
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKM 462
L YM+P + + PL NGK+DR LL M
Sbjct: 711 KLPDYMVPSDIFPIAEFPLNANGKLDRPALLAM 743
>UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1;
Streptomyces fungicidicus|Rep: Nonribosomal peptide
synthetase - Streptomyces fungicidicus
Length = 6943
Score = 197 bits (481), Expect = 8e-49
Identities = 164/537 (30%), Positives = 246/537 (45%), Gaps = 47/537 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA KAG AY+P++P P RI +++DA P LV+ D D
Sbjct: 2681 VIAALAVLKAGGAYLPVDPGQPAERIRSVIEDAAPVLVL--DHPD--------------- 2723
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + A DA+ ++PL A V+YTSGSTG PKGV +S+ ++
Sbjct: 2724 -FLAETADYDAAPVTDADRVSPLLPSHPAYVIYTSGSTGRPKGVVVSHRSVVALFVAAGG 2782
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + + ++ W +L F SV E+WG LLHG ++++ + +R P++ V + V
Sbjct: 2783 VFEFG-AGDVWSWFHSLAFDFSVWEVWGALLHGGRVVVVPFDVSRSPREFVELLERERVT 2841
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L ++ + L L L+ V GE L +++ FG E G +L N YG TE
Sbjct: 2842 VLSQTPSAFYQLMGVGGGLPALRTVVFGGEALEPGRLDGWWERFG-EAGPRLVNMYGITE 2900
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
VT+ L D IGR L +++LLDE L P GE++VAGA +A
Sbjct: 2901 TTVHVTHQDLRPDTAAD---GSVIGRGLPGLSVFLLDEWLRPVPVGAVGEMYVAGAQVAR 2957
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHRVD 376
GY G G RF P R+YRTGD + G +++AGR D QVKIRG R++
Sbjct: 2958 GYRGRAGLTGERFVACPFGVAG--GRMYRTGDRARWSREGRLVFAGRADEQVKIRGFRIE 3015
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG--ARTSAQHIEGKLRSALTH 434
EVE +A P V + V+ G ++ ++ +P A ++ + L
Sbjct: 3016 PGEVEAVVAGHPDVAQVAVVAREGGPGGLRLVAYIVPEPAEQAEGFSERVRVYAGERLPS 3075
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P + ++ +PL VNGK+DR L D+A V S
Sbjct: 3076 YMVPSAFVVLDGLPLTVNGKLDRTAL-------PEPDNAVV------SAGRAPVTAQEEL 3122
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
VLG G + F+ LGG+SL ++ + LR RG V + ++T
Sbjct: 3123 LCAAFAEVLGLDQVG---VDDDFFALGGHSLLAVSLVEWLRQRGVSVSVRALFASAT 3176
Score = 170 bits (414), Expect = 1e-40
Identities = 149/530 (28%), Positives = 240/530 (45%), Gaps = 51/530 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG A+VP++ +P+ R +++DA S+++ DD A A E
Sbjct: 569 VVALLAVVKAGGAFVPLDTGWPEARKRAVIEDAGASVMVVDDKA------------AGHE 616
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + D A + + A V+YTSGSTG+PKGV ++ + +
Sbjct: 617 QFGASLVAVGSGADSDVVLPASVAPGAAAYVMYTSGSTGVPKGVVATHRDVVRLAKDRCW 676
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP--QKLVNIERLVL 197
P ++ F S E+W PLL G +++ E ++LV+ +
Sbjct: 677 GAPAR-----VLFHAPHAFDASSYELWVPLLSGGTVVVAPDEAMDGAVLRRLVSDHGVSH 731
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + + P S ++ + G+ + E + G + YG
Sbjct: 732 VHVTAGLLRVLADQDPGS--FSGVREVLTGGDVVPAESVR---RVLDANPGVTVRQLYGP 786
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TEV T Y E +D ++ +PIGRPLDN +Y+LD LSP GE++VAGA +
Sbjct: 787 TEVTLCATQY--EVADAAEVDGVLPIGRPLDNTRVYVLDGALSPVPVGVAGELYVAGAGV 844
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+G RF P E R+YRTGD +G +++ GR D QVKIRG R
Sbjct: 845 ARGYLGRPVLTGERFVACPFGATGE--RMYRTGDLVRWDAEGRLVFMGRADDQVKIRGFR 902
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
V+ EVE +A P V + V+ G+ ++ ++ + A + L
Sbjct: 903 VEPGEVETVVAAHPAVGQAAVVVREDTPGDKRLVAYLVPAGTETSLADAVRAHTAERLPE 962
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGL-LKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
Y++P +E+E++PL +GK+DR+ L +Y + + A V ++ C
Sbjct: 963 YLVPSAFVELENLPLTPSGKLDRKVLPAPLYASGAGREPATVREELVC------------ 1010
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
VLG A+ G + F+ LGG+SL ++ + LR RG V +
Sbjct: 1011 ---RAFAEVLGLASVG---VEDDFFALGGHSLLAVSLVEWLRRRGVSVSV 1054
Score = 167 bits (406), Expect = 1e-39
Identities = 154/531 (29%), Positives = 243/531 (45%), Gaps = 49/531 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LA KAG Y+P++ +P R+ + +DA+ ++ + F V +
Sbjct: 4791 VVVFLAVLKAGGTYLPLDLGWPTARMRAVAEDADARCIVTHQATAGHEF----VRTTALS 4846
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E+ + + A E TL + + A V+YTSGSTG+PKGV ++ + RL +
Sbjct: 4847 EVRVDVIAGPAAEV----TLPLVDPGAAAYVMYTSGSTGVPKGVVATHRDVV-RL---AK 4898
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP--QKLVNIERLVL 197
+ D + ++ F S E+W PLL G +++ E ++LV++ L
Sbjct: 4899 DRCWGDPARV-LFHAPHAFDASTYELWVPLLSGGTVVVAPGEAIDGAVLRRLVSVHGLSH 4957
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + + P ++ + G+ ++ E + G + YG
Sbjct: 4958 VHVTAGLLRVLADQDPGC--FAGVREVLTGGDVVAAESVRRVLEA---NPGVGVRQLYGP 5012
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TEV T Y E +D ++ +PIGRPLDN +Y+LD LSP GE++VAGA +
Sbjct: 5013 TEVTLCATQY--EVADAAEVDGVLPIGRPLDNTRVYVLDGSLSPVPVGVAGELYVAGAGV 5070
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+G RF P A E R+YRTGD V+G +++ GR D QVKIRG R
Sbjct: 5071 ARGYLGRPVLTGERFVACPFAGAGE--RMYRTGDLVRWDVEGRLVFLGRADEQVKIRGFR 5128
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA-QHIEGKLRSALT 433
V+ EVE +A P V + VL G+ ++ ++ GA T+A + + L
Sbjct: 5129 VEPGEVETVVAAHPAVAQATVLVREDVPGDKRLVAYLVL-AGAETAAVDAVHTHVAEQLP 5187
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL-LKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
Y++P +E+E++PL GKVDR L Y A+ ++ C
Sbjct: 5188 SYLVPSAFVELETLPLTPTGKVDRAALPAPRYTAGTGRAPADAREELVC----------- 5236
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
VLG AA G + F+ LGG+SL ++ + LR RG V +
Sbjct: 5237 ----RAFAEVLGLAAVG---VEDDFFALGGHSLLAVSLVEWLRRRGVSVSV 5280
Score = 164 bits (398), Expect = 9e-39
Identities = 147/452 (32%), Positives = 211/452 (46%), Gaps = 51/452 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA KAG AY+P++P P RI +++DA P LVI D
Sbjct: 6422 VIAVLAVLKAGGAYLPIDPGQPAERIRSVIEDAAPVLVIDDP------------------ 6463
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E H+A DA+ ++PL A V+YTSGSTG PKGV +++ C L
Sbjct: 6464 DFLAETADHTAAPVTDADRVSPLLPSHPAYVIYTSGSTGRPKGVVVTHEG-CANLSASHD 6522
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWG-PLLHGRALLILSRETTRDPQK---LVN--IE 193
+ + + + A D CE W LL G L+ + + P LV+ +
Sbjct: 6523 WYGVAAGSRVAQF--ASVGFDMFCEEWLLALLRGATLVTVPADRRLGPDLGHFLVDQGVT 6580
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L P + +I L L P+ + GE EL + DG + N
Sbjct: 6581 HAALPPAVAATIPDGL-LDPSF-------VLDVGGEACPPELVERW-----TADGRTMFN 6627
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D T V + LD +PIGRP+ N Y+LD+ L P GE+ +A
Sbjct: 6628 AYGPTEATVDAT--VWRCAPGLDAGAAVPIGRPVLNTRAYVLDDALRPVPVGVVGELHLA 6685
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKI 370
G+ LA GY+G G A RF P QP +R+YRTGD G +++AGR D QVKI
Sbjct: 6686 GSGLARGYLGRTGLTAERFVACPF--QPG-RRMYRTGDRVKWDADGQLVFAGRADDQVKI 6742
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP--GARTSAQHIEGKL 428
RG R++ EVE LA P V + V G+ ++G+V A + + G
Sbjct: 6743 RGFRIEPGEVEAVLASHPDVARAAVTVREDSPGDLRLVGYVVPAEDVDAGELPRTVRGFA 6802
Query: 429 RSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
L YM+P V+ ++++PL NGK+DR+ L
Sbjct: 6803 GERLPSYMVPSAVVPLDALPLTPNGKLDRRAL 6834
Score = 158 bits (384), Expect = 5e-37
Identities = 150/451 (33%), Positives = 212/451 (47%), Gaps = 50/451 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA KAG AY+P++P P R+ +++DA P LV+ D+SA ++G
Sbjct: 1633 LVAILAVLKAGGAYLPIDPDQPAERVAFMIEDAAPVLVL-DESA-----LQAGAG----- 1681
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A A S DA+ LAPL A V+YTSGSTG PKGV +++ N L R
Sbjct: 1682 DRADSAVS-------DADRLAPLLPTHPAYVIYTSGSTGRPKGVVVTHEGFAN-LSLSHR 1733
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWG-PLLHGRALLIL--SRETTRDPQKLVNIERLV 196
F + + +A D CE W LL G AL+ + R D + + E V
Sbjct: 1734 RFEVGPGSRVAQFASA--GFDMFCEEWLLALLSGAALVTVPADRRLGADFAEFL-AESGV 1790
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
TL + + L G + GE L E S + G K+ N YG
Sbjct: 1791 THATLPPAAVATLPEGALDDGF----VLDVGGEALPAETVSRWAA------GRKMFNSYG 1840
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE V V L +PIGRP+ N +++LD+ L P GE++V G
Sbjct: 1841 PTETT--VNAAVWRCRSGLAAGAEVPIGRPIVNTRVHVLDDALRPVPAGVLGELYVTGTG 1898
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGH 373
LA GY+G G A RF P +P QR+YRTGD G +++AGR D QVKIRG
Sbjct: 1899 LARGYLGRAGLTAERFVACPF--EPG-QRMYRTGDRVKWNADGDLVFAGRADDQVKIRGF 1955
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL----R 429
R++ EVE LA P VD+ V+ G+P ++G+V P + L
Sbjct: 1956 RIEPGEVEAVLAAHPWVDRAAVVVREDTPGDPRLVGYVI--PAEDIDTHELPSLLTEFAA 2013
Query: 430 SALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
L +M+P V +++ PL N K+DR+ L
Sbjct: 2014 QRLPAHMVPSAVTTLDAFPLTPNAKLDRKAL 2044
Score = 158 bits (383), Expect = 6e-37
Identities = 134/450 (29%), Positives = 215/450 (47%), Gaps = 43/450 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG A++P++ ++PQ R+ +++DA LV+ ++ + G+
Sbjct: 3745 VVALLAVLKAGGAFLPLDATWPQARMRSVIEDAAACLVVVSETWAGH---DLGIT----- 3796
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAIC----NRLW 135
E+A +A S P+ E + A V+YTSGS G+PKGV ++ + +R W
Sbjct: 3797 EVAVDAGSDEGHLPVVPEA-------ATAYVMYTSGSAGVPKGVVAAHRDVVALAGDRCW 3849
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLIL--SRETTRDPQKLVNIE 193
+ ++ F S E+W PLL G +++ R T ++LV ++
Sbjct: 3850 ---------GAPARVLFHAPHAFDASSYELWVPLLSGGTVVVAPDGRMDTTVLRRLV-LD 3899
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V + +L LA ++ + G+ + E N D ++
Sbjct: 3900 HDVSHVHVTAGLLRVLA-DQDPGCFAGVREVLTGGDVVPAESVRRVLD--ANPD-VRVRQ 3955
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TEV T Y E +D ++ +PIGRPLDN +Y+LD L+P GE++VA
Sbjct: 3956 LYGPTEVTLCATQY--EVADAAEVDGVLPIGRPLDNTRVYVLDGALNPVPVGVAGELYVA 4013
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
GA +A GY+G RF P E R+YRTGD +G +++ GR D QVKI
Sbjct: 4014 GAGVARGYLGRPVLTGERFVACPFGGAGE--RMYRTGDLVRWDAEGRLVFVGRADEQVKI 4071
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG RV+ EVE L P V + V+ G+ ++ ++ + T +
Sbjct: 4072 RGFRVEPAEVEAVLGAHPAVGQAAVVAREDTPGDKRLIAYLVPQNEGETLDGPVREYAAE 4131
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P +E++++PL VNGK+DR+ L
Sbjct: 4132 RLPEYMLPAAFVELDTLPLTVNGKLDRKAL 4161
>UniRef50_UPI000045BBC7 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide
synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1420
Score = 197 bits (480), Expect = 1e-48
Identities = 154/529 (29%), Positives = 253/529 (47%), Gaps = 40/529 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++L KAG AYVP++P++P+ R+ +L DA+ S+++ +D F E G+P +
Sbjct: 850 VVSILGILKAGGAYVPLDPTYPKERLAFMLSDAQVSVLLTEDK-----FLE-GLPEHQAQ 903
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ S + + + +T++++A V+YTSGSTG PKGV +++ +
Sbjct: 904 VVCLNQNSEAWCQERVDNPVREVTTNNLAYVIYTSGSTGKPKGVLVNHQNVIRLFTATQS 963
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI----E 193
F +SD + VW + F SV EIWG LL+G L+++ +R P+ N+ +
Sbjct: 964 WFNFSDRD---VWTNFHSYGFDFSVWEIWGSLLYGGRLVVVPYWISRSPEAFYNLLCTQQ 1020
Query: 194 RLVL--VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
VL P+ R ++ L+L + GETL + +F+ G DG +L
Sbjct: 1021 VTVLNQTPSAFRQLMNAEEEAAGKTGTLALRLVIFGGETLELDSLQPWFERHG--DGSQL 1078
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE VTY + +D ++ IG + + IYLLD + P GE++
Sbjct: 1079 VNMYGITETTVHVTYRPINIADLNQRNGSL-IGHRIPDLQIYLLDSQRQPVPIGVAGELY 1137
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
+ GA + GY+ A RF NP + + LY++GD L G + Y GR D QV
Sbjct: 1138 IGGAGVTRGYLNRPELTAERFIVNPFSEVTDAY-LYKSGDLARYLPNGELEYLGRIDHQV 1196
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG R++L E+E AL + V + +V G ++G+V + ++ L
Sbjct: 1197 KIRGFRIELGEIETALRKHQAVREVIVQAVEESHGEKRLVGYVVLDDKQAVTIGDLQRFL 1256
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
+ L YM+P I + ++PL NGK+DR+ L N DA V +
Sbjct: 1257 KEKLPEYMVPSAFIFLPALPLTPNGKLDRRSLPAPETIRPNLSDAYVMPQTEME------ 1310
Query: 488 XXXXXXXXXTVGAVLGRAAR-GTLSLRSGFYELGGNSLNSIYTITKLRD 535
T+ + +A + + F+ELGG+SL + +KLR+
Sbjct: 1311 --------QTIATIWQKALNIEKIGIHDNFFELGGHSLLMVKVHSKLRE 1351
>UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC
7120|Rep: All1695 protein - Anabaena sp. (strain PCC
7120)
Length = 1449
Score = 197 bits (480), Expect = 1e-48
Identities = 164/569 (28%), Positives = 272/569 (47%), Gaps = 33/569 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA KAG AY+P++ S P R+ I+KDAE ++I +S + K + +
Sbjct: 94 IIAILAILKAGGAYLPLDISAPLERLETIIKDAEAFILITQESQLNYLEKITD----EIQ 149
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S+ D D + +T+ ++A V+YTSGSTG PKGV + + + + +
Sbjct: 150 TICIDNQSNLTDFSDDISLCSEVTAHNLAYVMYTSGSTGKPKGVCVEHRGVVRLV--KNT 207
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ +E+ + ++ F + EIW LL+G L+++ + + I++ +
Sbjct: 208 NYANFSCDEVILQLASIAFDAATFEIWAALLNGGKLVLMPINIPSLQEIGMAIKQYHVTT 267
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L L + L+ L+ + G+ LS S+ + N +L N YG TE
Sbjct: 268 LWLTAGLFNLMVEEQIEHLKSLRQLLAGGDVLSVYHVSKVIEELPN---CQLINGYGPTE 324
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ + +D + +IPIGRP+ N +Y+LD+ L GE+++ G LA
Sbjct: 325 NTTFTCCHKITVNDLIK--DSIPIGRPIANTQVYILDDVLQLVPIGIAGELYIGGDGLAR 382
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ A +F +P + +P RLY+TGD L G + + GR D QVKIRG RV+
Sbjct: 383 GYLNKPDLTAEKFIPHPFSDKPN-SRLYKTGDRVRWLPDGTIEFLGRIDFQVKIRGFRVE 441
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA-QHIEGKLRSALTHY 435
L E+E LAQ P V VVL + ++ + T + T A + L+ L +Y
Sbjct: 442 LGEIEAILAQHPSVRSAVVLAQEYQPADKRLVAYFTREENCNTVAPSELRHFLQQKLPNY 501
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P I +E +PL NGKVDR+ L N D ++ +D D S
Sbjct: 502 MIPSAFISLEKLPLNANGKVDRKAL-------PNVD--KICIDTD-SNFVSPRTPTEARL 551
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD-RGYYVEISDFLGASTLGE 553
VLG + + F E+GG+SL+S ++++RD G + + L AST+ E
Sbjct: 552 ASIWADVLGT----QVGIYQPFLEVGGHSLHSTQIVSRVRDCFGINLPVYAVLEASTIAE 607
Query: 554 VLSKMSTDPNGGADSKEATFTAVPMRDEH 582
LS+ P+ K++ P+ ++
Sbjct: 608 -LSRWIESPDQQQQPKQSVPALQPISHQN 635
>UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|Rep:
Amino acid adenylation - Frankia sp. (strain CcI3)
Length = 4489
Score = 197 bits (480), Expect = 1e-48
Identities = 149/447 (33%), Positives = 221/447 (49%), Gaps = 25/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AY+P++P +P R+ +L DA+P +V+ G+P
Sbjct: 1580 VVALLAVVKAGGAYLPVDPEYPASRVGLMLADADPVVVLCTAET------VGGLPEHPAV 1633
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + D P + + + A V+YTSGSTG+PKGV +S+ I NRL W
Sbjct: 1634 RLMVDDGGVVRDCPGTSPGVV-VRPGCPAYVMYTSGSTGVPKGVVVSHRGIVNRLLWMQG 1692
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLV 196
+ + + + KT+ F SV E + PL+ G L++ RDP+ LV++ ER+
Sbjct: 1693 EYGLGGDDRV-LQKTSSGFDVSVWEFFWPLVTGACLVVARPGGHRDPRYLVDLVVAERVT 1751
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + + ++L A+ L+ VCSGE L EL F G G L N YG
Sbjct: 1752 TVHFVPSMLGLFLDEEGAAL-CGGLRRVVCSGEVLPGELVERFQ---GVLPGVGLHNLYG 1807
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DV+++ + +PIG P+ N +++LD L P GE+++AG
Sbjct: 1808 PTEASVDVSFWACPPG----VSGVVPIGGPIWNVRLFVLDGFLRPVPPGVVGELYIAGVG 1863
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGH 373
LA GYVG RF P + E R+YRTGD G ++Y GR DAQVKIRG
Sbjct: 1864 LARGYVGRSSLTGERFVACPFSGSGE--RMYRTGDLVRWRGDGVLVYVGRVDAQVKIRGL 1921
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L EVE LA V + V+ G+ ++ +V G A + L
Sbjct: 1922 RIELGEVEAVLAGDGAVGRVAVVVREDQPGHRYLVAYVVAAAGRGVDAAGLREFAARRLP 1981
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P V+E+ +PL ++GK+DR+ L
Sbjct: 1982 EYMVPAAVVELAELPLTLSGKLDRKAL 2008
Score = 177 bits (430), Expect = 1e-42
Identities = 138/450 (30%), Positives = 210/450 (46%), Gaps = 19/450 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA-SF 78
++ALLA KAGAAY+P++P +P R +L DA P + + ++ + V
Sbjct: 3701 VVALLAVLKAGAAYLPVDPEYPAARQAFMLADAAPVVTLGTARTVGALPEHGAVRVVVDA 3760
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + DAE + L A V+YTSGSTG PKGV + + +
Sbjct: 3761 PDTVRVLAGLPGTAVRDAERVRSLRPGHPAYVIYTSGSTGTPKGVLIPQRNVAALIETAG 3820
Query: 139 RTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
R + + VW + F SV E++G LL G +++++ +R P++ V +
Sbjct: 3821 RVYGLGADD---VWSLFHSYAFDFSVWEMFGALLLGGRVVVVAHSVSRSPREFVELLSRT 3877
Query: 197 LVPTLLRS-ILMYLALGP--ASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V L ++ Y +G A+ L+ V GE L +++ + D L N
Sbjct: 3878 GVTVLSQTPSAFYQVIGELAAAGVGSSLRYVVFGGEALEPARLRQWYDRYPG-DVPVLVN 3936
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VT+ L+ + ++ +G PL Y+LDE L P GE++VA
Sbjct: 3937 MYGITETTVHVTHIALDRERVVAGTGSV-VGGPLPGVRTYVLDEFLRPVPPGVVGELYVA 3995
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKI 370
GA LA GY+ RF P E R+YRTGD G +++AGR DAQVKI
Sbjct: 3996 GAGLARGYLNRPALTGERFVACPFGGSGE--RMYRTGDLARWTGDGGLVFAGRADAQVKI 4053
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++ E+E L+ P VD+ V+ G+ ++ ++ P A I +
Sbjct: 4054 RGFRIEPGEIEAVLSGHPAVDQVAVVMREDQPGHRHLVAYLV--PHQEIGAAEIRAFVAG 4111
Query: 431 ALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
L YM+P V+EV +PL NGK+DR L
Sbjct: 4112 RLPEYMVPAVVVEVAELPLTANGKLDRAAL 4141
Score = 161 bits (392), Expect = 5e-38
Identities = 133/450 (29%), Positives = 205/450 (45%), Gaps = 36/450 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ L+ K GAAYVP++ +P R+ +L +A +V+ D + GV +A
Sbjct: 529 VAVLVGVVKVGAAYVPVDVEWPVVRVGRVLAEAGVRVVVADVGVS-DLPGSVGVVWAG-- 585
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAI----CNRLW 135
E + +D +A V+YTSGSTG+PKGV ++++ + +R W
Sbjct: 586 -------GWVDGEGECGPPAVRVGADDVAYVMYTSGSTGVPKGVAVTHAGVVGLAADRCW 638
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
+ + ++ + F S E+W LL G +++ D L +
Sbjct: 639 SR-------EVHGRVLFHASHAFDASTWELWVALLSGGQVVVAPAGRV-DAGVLKGLIS- 689
Query: 196 VLVPTLLRSILMYLALGPASRP--LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
PT++ A P ++ V G+ +S A+ + G +
Sbjct: 690 DFGPTVVHVTAGLFAAVAEEAPGCFVGVREVVTGGDVVS---AAAVVRVVEACPGVVVRQ 746
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TEV T + + D++ +PIGRP+DN +++LD L P GE++VA
Sbjct: 747 LYGPTEVTVCATVFEVRPGDEVA--SVVPIGRPMDNTRVFVLDRFLQPVPPGVTGELYVA 804
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKI 370
G LA GY G G RF P + E R+YRTGD G +G +++AGR D QVK+
Sbjct: 805 GVGLARGYFGRPGLTGERFVACPFSGSGE--RMYRTGDLGRWTGEGQLVFAGRVDGQVKV 862
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L EVE L PGV +CVV+ + G ++ +V G I +
Sbjct: 863 RGFRIELGEVEAVLGLYPGVGRCVVVVREDEPGQKRLVAYVVASEGEALDTVQIRDFVAG 922
Query: 431 ALTHYMMPQVIEVES-IPLLVNGKVDRQGL 459
L YM+P V+ V S +PL GKVDR L
Sbjct: 923 LLPEYMVPAVVVVLSGLPLTGQGKVDRGAL 952
Score = 158 bits (383), Expect = 6e-37
Identities = 138/448 (30%), Positives = 213/448 (47%), Gaps = 34/448 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA K GAAY+P++ +P R+ +L DA+P+ V+ ++ V +
Sbjct: 2641 LVALLAVLKTGAAYLPVDVGYPSSRVAFMLADADPAAVVCTAETARALPGHPAVRTVLDD 2700
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EA + A +P + + P A V+YTSGSTG PKGV +S+ + L R
Sbjct: 2701 PRTAEAPA--ARQPTASGRIDPRHP---AYVIYTSGSTGTPKGVVISHRNLVTFLA-AMR 2754
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL----VNIERL 195
P ++ + T L F + E++ PL+ G +++ RE DP++L V
Sbjct: 2755 IRPGLTEADVLLAVTTLGFDIAGLELFLPLVVGGRVVVAEREVALDPRRLAAEIVRHSAT 2814
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
VL T + + M + G A P LK +C GE L +LA E ++ N Y
Sbjct: 2815 VLQATPV-TWRMLVDDGWAGSP--GLKA-LCGGEALPPDLAEAMI-----ERCAQVWNMY 2865
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE + QL + +G P+ Y+LD+ L P GE+++AG
Sbjct: 2866 GPTETT------IWSTCRQLTAGGGVSLGTPIAGTRTYVLDDLLQPVPPGVVGELYLAGP 2919
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
LA GY G RF P + E R+YR+GD G +++ GR D Q+KIRG
Sbjct: 2920 GLARGYWARAGLTGERFVACPFSGSGE--RMYRSGDLVRWTAAGELVFVGRADTQLKIRG 2977
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
RV++ EVE LA PGV + VV+ G+ ++G+V PG + + L
Sbjct: 2978 FRVEVGEVEAVLAVFPGVTRVVVVAREDRPGHRYLVGYVV--PG-DVDGRAVREFAAERL 3034
Query: 433 THYMMPQ-VIEVESIPLLVNGKVDRQGL 459
Y++P V+ + ++P+ NGK+DR L
Sbjct: 3035 PEYLVPAGVVALPALPVTPNGKLDRGAL 3062
>UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1;
Streptomyces anulatus|Rep: Actinomycin synthetase II -
Streptomyces chrysomallus
Length = 2611
Score = 196 bits (479), Expect = 1e-48
Identities = 147/452 (32%), Positives = 228/452 (50%), Gaps = 24/452 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA KAGAAY+P++P +P R+ H++ DA+P+L++ + + P +
Sbjct: 527 VVAVLAVLKAGAAYLPLDPEYPANRLAHMVTDAQPTLILTTTETEAKLPDRHTAPALRLD 586
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E + A +P ++ + L D A V+YTSGSTG+PKGV ++ + RL+
Sbjct: 587 D--PETLAALAGQPANSPAVG-LRPDHPAYVIYTSGSTGVPKGVVNTHRNVV-RLF--DA 640
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERL 195
T P+ D VW + F SV E+WG LLHG L+++ + +R P +++ ++
Sbjct: 641 TRPWFDFGPDDVWTLFHSYAFDFSVWELWGALLHGGRLVVVPYDVSRSPHAFLDLLADQG 700
Query: 196 VLVPTLLRSILMYLALGPA--SRPLRRLKL--WVCSGETLSKELASEFFKYFGNEDGYKL 251
V V S LA A RP RRL L V GE L +E+++ ED +L
Sbjct: 701 VTVLNQTPSAFHQLAQAAADPGRPPRRLALRTVVFGGEALQPARLAEWYRRH-PEDTPQL 759
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE VT+ L D+ IG + + ++LD L GE++
Sbjct: 760 VNMYGITETTVHVTHQPLT-RDRAAAGAASVIGAGISDLRTHVLDGGLQLVPPGAVGELY 818
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQV 368
VAG LA GY+G A RF +P+ R+YRTGD G + + GR D QV
Sbjct: 819 VAGPGLARGYLGRPALTAERFVADPYGAPG--ARMYRTGDLVRRNPDGELEFVGRADHQV 876
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L EVE AL P V++ V+ G+ ++ +V + R + +
Sbjct: 877 KVRGFRIELGEVEAALLAHPDVEQATVIVREDRPGDTRLVAYVVGREALR--PEQVREFT 934
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
R L +M+P V+++E +PL NGK+DR L
Sbjct: 935 RERLPEHMVPAAVVQLERLPLTPNGKLDRAAL 966
Score = 145 bits (352), Expect = 3e-33
Identities = 130/448 (29%), Positives = 198/448 (44%), Gaps = 34/448 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T+ +LA K GA Y+P++ +P RI +L + L+I D + D +
Sbjct: 1595 TVTTVLALAKTGATYIPLDSRYPADRIRLVLDETRTKLLITDHTTDLD---------TTT 1645
Query: 79 EELAQEATSHSADEPMDAE-TLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ T H ++P + T P D A ++YTSGSTG PKGV ++ I L
Sbjct: 1646 TQFNPADTPHDGEDPGNPNHTTHP---DDAAYIMYTSGSTGRPKGVIATHRNI-TALALD 1701
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRET--TRDPQKLVNIERL 195
R P + + TA F S EIW PLL+G +++ +++ +++
Sbjct: 1702 PRFDPTAHRRVLLHSPTA--FDASTYEIWVPLLNGNTVVLAPTGDLDVHTYHRVITDQQI 1759
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
V + PA R ++W GE +S A + + + Y
Sbjct: 1760 TAVFLTTALFNLLTEHDPACLAGVR-EVWT-GGEAVS---AFSVRRVQEACPSVVVVDVY 1814
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T+ + + IGRP+ Y+LD+ L P GE+++ GA
Sbjct: 1815 GPTETTTFATHNPVP--TPYTGPAVVAIGRPMATMHAYVLDDALQPVAPGVVGELYLGGA 1872
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRG 372
LA GY+ A RF NPH +P +R+YRTGD A L + GR D QVK+RG
Sbjct: 1873 GLARGYLDRPALTAERFVANPH--RPG-ERMYRTGDLARWSADAQLEFVGRADQQVKVRG 1929
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++ E+E L P V + +L G P ++ +V G T+ + LR L
Sbjct: 1930 FRIEPGEIENVLTGHPAVAQAAILVREDQPGRPRLVAYVVADGG--TAPDGLREALRRRL 1987
Query: 433 THYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + ++ +PL NGKVDR L
Sbjct: 1988 PEYMVPSAFVVLDRLPLTANGKVDRAAL 2015
>UniRef50_Q4ZV21 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=3; Pseudomonas syringae group|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 2666
Score = 196 bits (478), Expect = 2e-48
Identities = 174/569 (30%), Positives = 272/569 (47%), Gaps = 52/569 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVP-FASF 78
I+ LLA KAG AYVP++P +PQ R++ ++ D+ L++ S+ + +P
Sbjct: 2117 IVGLLAILKAGGAYVPLDPDYPQDRLSFLMHDSGIELLL----TQASLLGKLPIPEQVQM 2172
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+LA E +S +P++ AP D++A V+YTSGSTG PKG L++ +
Sbjct: 2173 LDLADELDDYSTADPIN--QTAP---DNLAYVIYTSGSTGKPKGTLLAHHNLMRLFAATD 2227
Query: 139 RTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL--VNIER 194
F +S+ + VW + F SV EI+G LLHG L+I+ RE TR P+ + +E+
Sbjct: 2228 EWFEFSEKD---VWTLFHSFAFDFSVWEIFGALLHGGRLVIVPREVTRSPEDFHALLVEQ 2284
Query: 195 LVLV----PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
V V P+ + LM++A +S P+ L+ + GE L +F FG++ +
Sbjct: 2285 QVTVLNQTPSAFKQ-LMHVAC-DSSLPM-SLQTVIFGGEALDVASLKPWFARFGDQSP-Q 2340
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE V+Y + +D + P PIG + + + Y+LD + +P GE+
Sbjct: 2341 LINMYGITETTVHVSYRPITLADTQN--PASPIGEAIPDLSWYVLDADFNPVAQGCSGEL 2398
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQ 367
+ A LA GY A RF +P + E RLYRTGD G + YAGR D Q
Sbjct: 2399 HIGHAGLARGYHNRAALTAERFVPDPFSN--EGGRLYRTGDLARYRATGVIDYAGRIDHQ 2456
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VKIRG R++L E+E L P V + VL LD L T + ++ +
Sbjct: 2457 VKIRGFRIELGEIEARLQAHPAVREVSVL--ALDGQLAAYLVPAEPDQDQPTLREMLKNE 2514
Query: 428 LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
LR+ L YM+P I ++S+PL NGK+DR+ L DA
Sbjct: 2515 LRAHLPDYMVPTHFIVLDSMPLTANGKLDRKAL--------PAPDAS-----QLQATYSA 2561
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDF 545
+ A L + R + F+ELGG+SL ++ + ++R++ + V + D
Sbjct: 2562 PQGELEQQLAAIWADLLQVER--VGRNDNFFELGGHSLLAVQMLVRVREQLQHEVSLKDV 2619
Query: 546 LGASTLGEVLSKMSTDPNGGADSKEATFT 574
L + + + + NG +D + T
Sbjct: 2620 FEQPLLADFCATLQ-EKNGESDHAQDELT 2647
Score = 108 bits (260), Expect = 5e-22
Identities = 63/188 (33%), Positives = 106/188 (56%), Gaps = 8/188 (4%)
Query: 280 TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHAT 337
++P+G PL + Y+LD+ L+P GE+++ G ++A GY+G A RF +P A
Sbjct: 875 SVPVGTPLPGASAYVLDDVLNPVGTQVAGELYIGGDSVALGYIGQPALTAERFVPDPFA- 933
Query: 338 QPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVL 396
+ R+YR+GD +G + + GR D QVK+RG+RV+ EV R L + V + VL
Sbjct: 934 -QDGTRVYRSGDRMRRNHQGLLEFIGRADDQVKVRGYRVEPAEVARVLLGLASVAQVSVL 992
Query: 397 CYGL--DRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGK 453
+ D+ +++ + GA S + +L + L YM+P Q++ ++S+PL NGK
Sbjct: 993 ALPIDDDQARLQLVAYCVAAGGADLSIDSLREQLTACLPDYMVPAQIMLLDSLPLTANGK 1052
Query: 454 VDRQGLLK 461
+D++ L K
Sbjct: 1053 LDKRALPK 1060
Score = 62.9 bits (146), Expect = 3e-08
Identities = 65/263 (24%), Positives = 114/263 (43%), Gaps = 20/263 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+LA +KAG Y+P++ P R+ +L +A+ +++ + +++ + A +
Sbjct: 565 LTAVLAIFKAGGVYMPLDVKAPDARLQQMLINAQARVLLCAEGD----VRQTSLGVAGCQ 620
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L D P+ P ++DS A V++TSGSTG PKGV +S A+ + L
Sbjct: 621 GLTWTPALWQ-DLPVSRPDTRP-SADSAAYVIHTSGSTGQPKGVLVSQGALASYLRGLLE 678
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+ + + T + ++G L GR L +L+ DP +
Sbjct: 679 QLHLAPEASMALVSTIAADLGHTV-LFGALCSGRTLHVLTEALGFDPDAFAAYMAEHQVG 737
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L +VP L ++L G + L + L + GE S L + + + G ++ N
Sbjct: 738 VLKIVPGHLAALLQ---AGQPADVLPQHAL-IVGGEACSPALVEQLRQL---KPGCRVIN 790
Query: 254 FYGSTEVMGDVTYYVLEGSDQLD 276
YG +E V Y + S LD
Sbjct: 791 HYGPSETTVGVLTYEVPASSCLD 813
>UniRef50_Q216S9 Cluster: Amino acid adenylation; n=1;
Rhodopseudomonas palustris BisB18|Rep: Amino acid
adenylation - Rhodopseudomonas palustris (strain BisB18)
Length = 1103
Score = 196 bits (478), Expect = 2e-48
Identities = 170/548 (31%), Positives = 251/548 (45%), Gaps = 47/548 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPS-LVIYDDSADPSMFKESGVPFASF 78
++A+LA KAGAAY+P++PSFP RI ILKD L+ +S + +P
Sbjct: 550 VVAILAVLKAGAAYLPIDPSFPPQRIDFILKDGGVRCLLAASESPSDPQGQRGPLPVIRV 609
Query: 79 EELAQEA-TSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
++ A A D D E A V+YTSGSTG PKGV +S+ A+ N L +
Sbjct: 610 DDAASYAGPGIDPDHSFDPERAA--------YVIYTSGSTGHPKGVVVSHRALMNTL--E 659
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLV 196
F Y + + ++KT TF S E++G L L +L RD + L+ IE+
Sbjct: 660 FLEASYPLAGKTILFKTNFTFDVSAAELFGWLFDNGRLAVLDLGAERDSRALLEAIEKFA 719
Query: 197 L-----VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ VP++L +L G AS PL RL+ +GE L +L + F + +L
Sbjct: 720 VTHVNFVPSMLDVLLESQPAGAAS-PLDRLRYVFAAGEALKPDLVNRFHRLVPK---VRL 775
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE TY+ L + ++PIGRP+ N ++LDE L P GE+
Sbjct: 776 ENLYGPTEAAIYATYHSLPRGAEAT---SVPIGRPISNTGAHILDEALRPVPVGVIGELC 832
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQV 368
++G LA Y+ A RFC +P +RLYRTGD G + Y GR D QV
Sbjct: 833 LSGVGLATEYLTRPDLTAERFCPSPDLAG---RRLYRTGDLAKWGDDGLIYYLGRADRQV 889
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG RV++ EVE+ L G+ + V G ++ ++ TS + I L
Sbjct: 890 KIRGFRVEVAEVEQKLRACDGIAEAAVTVRSDAFGQNSLVAYLAFDKDRPTSIERISSDL 949
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
L +M+P+ + ++ +P L +GK+D + L A +
Sbjct: 950 VGWLPGFMIPEAFVPLDRLPRLPSGKIDIRRL-----------PAPTLTGAPATPAQRAA 998
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEISDFL 546
+L RG L+ S F+ LGGNSL ++ I L + G + DFL
Sbjct: 999 TELERKIIAIAEDLLD--LRG-LTPASNFFHLGGNSLLTLRFIAALDKALGTRLRAMDFL 1055
Query: 547 GASTLGEV 554
T+ E+
Sbjct: 1056 RLPTIAEI 1063
>UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces
filamentosus|Rep: Peptide synthetase 1 - Streptomyces
filamentosus (Streptomyces roseosporus)
Length = 5830
Score = 196 bits (477), Expect = 2e-48
Identities = 153/459 (33%), Positives = 214/459 (46%), Gaps = 30/459 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA K GAAYVP++P +P R+ +++ DA P+ V+ + A
Sbjct: 4207 IVALLAVTKTGAAYVPLDPEYPTDRLAYMVTDANPTAVVTSTDVHIPLI-------APRI 4259
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL EA D A V+YTSGSTG PKGV +S++ +
Sbjct: 4260 ELDDEAIRTELAAAPDTAPCVGSGPAHPAYVIYTSGSTGRPKGVVISHANVVRLFTACSD 4319
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERL 195
+F + VW + F SV EIWG LLHG L+++ E TR P + + + E+
Sbjct: 4320 SFDFGPDH---VWTLFHSYAFDFSVWEIWGALLHGGRLVVVPFEVTRSPAEFLALLAEQQ 4376
Query: 196 VLVPTLLRSILMYLALGPASRPLR----RLKLWVCSGETLSKELASEFFKY-FGNEDGYK 250
V + + S L P R L+ V GE L ++F G+
Sbjct: 4377 VTLLSQTPSAFHQLTEAARQEPARCAGLALRHVVFGGEALDPSRLRDWFDLPLGSRP--T 4434
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE VT LE D+ PIGRPL + +Y+LDE L P GE+
Sbjct: 4435 LVNMYGITETTVHVTVLPLE--DRATSLSGSPIGRPLADLQVYVLDERLRPVPPGTVGEM 4492
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQ 367
+VAGA LA GY+G A RF +P++ RLYRTGD + G + Y GR D Q
Sbjct: 4493 YVAGAGLARGYLGRPALTAERFVADPNSRSG--GRLYRTGDLAKVRPDGGLEYVGRGDRQ 4550
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEG 426
VKIRG R++L E+E AL GV + VVL + ++ V P + +
Sbjct: 4551 VKIRGFRIELGEIEAALVTHAGVVQAVVLVRDEQTDDQRLVAHVVPALPHRAPTLAELHE 4610
Query: 427 KLRSALTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYE 464
L + L YM+P ++ +PL NGK+DR L ++
Sbjct: 4611 HLAATLPAYMVPSAYRTLDELPLTANGKLDRAALAGQWQ 4649
Score = 189 bits (461), Expect = 2e-46
Identities = 173/603 (28%), Positives = 265/603 (43%), Gaps = 66/603 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ LL + GAAY+P++ +P R+ H+L DA P LV+ +G+
Sbjct: 5279 VTTLLGVLRTGAAYLPLDTGYPAERLAHVLSDARPDLVL----------THAGLAGRLPA 5328
Query: 80 ELAQEATSHSADEPMDAETLAPLT--SDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
LA P A P + D +A V++TSGSTG PKGV ++ S++ L
Sbjct: 5329 GLAPTVLVDEPQPPAAAAPAVPTSPSGDHLAYVIHTSGSTGRPKGVAIAESSLRAFLADA 5388
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ER 194
R + + + T + F + E++ PLL G A+++ + RDP + ++
Sbjct: 5389 VRRHDLTPHDRLLA-VTTVGFDIAGLELFAPLLAGAAIVLADEDAVRDPASITSLCARHH 5447
Query: 195 LVLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ +V P+ R++L A+R L +++ V GE L +LA G +
Sbjct: 5448 VTVVQATPSWWRAMLDGAPADAAAR-LEHVRILV-GGEPLPADLARVL-----TATGAAV 5500
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE T L D T IG PLDN +++LD L P PGE+
Sbjct: 5501 TNVYGPTEATIWATAAPLTAGDDR----TPGIGTPLDNWRVHILDAALGPVPPGVPGEIH 5556
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+AG+ LA GY+ A RF NP A +R+YRTGD G G + + GR D QV
Sbjct: 5557 IAGSGLARGYLRRPDLTAERFVANPFAPG---ERMYRTGDLGRFRPDGTLEHLGRVDDQV 5613
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR-TSAQHIEGK 427
K+RG R++L +VE ALA+ P V + RG ++ +V +PG R A +
Sbjct: 5614 KVRGFRIELGDVEAALARHPDVGRAAAAVRPDHRGQGRLVAYVVPRPGTRGPDAGELRET 5673
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
+R L YM+P + + ++P NGK+DR L A
Sbjct: 5674 VRELLPDYMVPSAQVTLTTLPHTPNGKLDRAAL--------------PAPVFGTPAGRAP 5719
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
+LG G S GF++LGG+S+ SI +++ R G ++ + D
Sbjct: 5720 ATREEKILAGLFADILGLPDVGADS---GFFDLGGDSVLSIQLVSRARREGLHITVRDVF 5776
Query: 547 GASTLGEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMVESSFYEKAELEQFLKH 606
T+G + + P AD VP D V+ + +E+ ELE L+
Sbjct: 5777 EHGTVGALAAAALPAPADDADD------TVPGTD-----VLPSISDDEFEEFELELGLEG 5825
Query: 607 EIE 609
E E
Sbjct: 5826 EEE 5828
Score = 174 bits (423), Expect = 9e-42
Identities = 156/534 (29%), Positives = 241/534 (45%), Gaps = 38/534 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA K GAAYVP++ + P R +L D P++++ D A + + E
Sbjct: 1562 LVALLAVLKTGAAYVPLDLTHPAERTAVVLDDCRPAVILTDAGAARELPRRDIPQLRLDE 1621
Query: 80 ELAQEATSHSADEPM---DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
A + P+ D + P++ + +A V+YTSGSTG PKGV + + ++ + + +
Sbjct: 1622 PEVHAAIAEQPGGPVTDRDRTCVTPVSGEHVAYVIYTSGSTGRPKGVAVEHRSLADFVRY 1681
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+P + ++ + + +TF +V ++ PL+ G A+ + T P L
Sbjct: 1682 SVTAYP--GAFDVTLLHSPVTFDLTVTSLFPPLVVGGAIHVADL-TEACPPSLAAAGG-- 1736
Query: 197 LVPTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
PT +++ +L L K+ + GE L L E K+ + N Y
Sbjct: 1737 --PTFVKATPSHLPLLTHEATWAASAKVLLVGGEQL---LGRELDKWRAGSPEAVVFNDY 1791
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE + + ++ + P + IGRPL N +++LD L GE+ VAG
Sbjct: 1792 GPTEATVNCVDFRIDPGQPIGAGP-VAIGRPLRNTRVFVLDGGLRAVPVGVVGELHVAGE 1850
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
LA GY+G G A RF P E R+YRTGD G + + GR D QVK+RG
Sbjct: 1851 GLARGYLGQPGLTAERFVACPFGDAGE--RMYRTGDLVRWRADGMLEFVGRVDDQVKVRG 1908
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK-PGARTSAQHIEGKLRSA 431
R++L EVE A+A PGVD+ VV+ G+ ++ +VT A A I
Sbjct: 1909 FRIELGEVEAAVAACPGVDRSVVVVREDRPGDRRLVAYVTAAGDEAEGLAPLIVETAAGR 1968
Query: 432 LTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L YM+P V+ ++ IPL NGKVDR L VA +
Sbjct: 1969 LPGYMVPSAVVVLDEIPLTPNGKVDRAAL----------PAPRVA---PAAEFRVTGSPR 2015
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISD 544
VLG G + GF++LGG+S+ SI + + R G V + D
Sbjct: 2016 EEALCALFAEVLGVERVG---VDDGFFDLGGDSILSIQLVARARRAGLEVSVRD 2066
Score = 171 bits (416), Expect = 6e-41
Identities = 137/445 (30%), Positives = 206/445 (46%), Gaps = 32/445 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
++ LL +AGAAYVP++P+ P R+ +L D P ++ D G+ +
Sbjct: 521 SVAILLGIQRAGAAYVPLDPTHPAERLARVLDDTRPRYLVTTGHID-------GLSHPTP 573
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ A + EP AP + A ++ TSGSTG PKGV +++ + Q
Sbjct: 574 QLAAADLLREGGPEPAPGRP-AP---GNAAYIIQTSGSTGRPKGVVVTHEGLATLAADQI 629
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
R + + + + F V E+ LL G L+I T V
Sbjct: 630 RRYRTGPDARVLQFISP-GFDVFVSELSMTLLSGGCLVIPPDGLTGRHLADFLAAEAVTT 688
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+L L A PA+ L L+ + GE E+ F +G G + N YG T
Sbjct: 689 TSLTPGAL---ATMPAT-DLPHLRTLIVGGEVCPPEI----FDQWGR--GRDIVNAYGPT 738
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + T + +G+ + +P+GRP N Y+LD L P D GE+++AG LA
Sbjct: 739 ETTVEATAWHRDGAT----HGPVPLGRPTLNRRGYVLDPALEPVPDGTTGELYLAGEGLA 794
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHRV 375
GYV G A RF +P P R+YRTGD G +L + GR D QVK+RG R+
Sbjct: 795 RGYVAAPGPTAERFVADPFG--PPGSRMYRTGDLVRRRSGGMLEFVGRADGQVKLRGFRI 852
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L EV+ AL +PGV + VL G+P ++G++ PGA A + L L +
Sbjct: 853 ELGEVQAALTALPGVRQAGVLIREDRPGDPRLVGYIVPAPGAEPDAGELRAALARTLPPH 912
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGL 459
M+P ++ + ++PL NGK+DR L
Sbjct: 913 MVPWALVPLPALPLTSNGKLDRAAL 937
Score = 151 bits (367), Expect = 5e-35
Identities = 133/451 (29%), Positives = 215/451 (47%), Gaps = 30/451 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ LLA K+G Y+P++P +P RI +L DA L + ++ ++ +
Sbjct: 3141 VAMLLAVAKSGGFYLPVDPQWPTERIDWVLADAGIDLAVVGENLAAAVEAVRDCEVVDYA 3200
Query: 80 ELAQEA-----TSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
++A+E + A + D E ++ L S V+YTSGSTG+PKGV ++++++ L
Sbjct: 3201 QIARETRLNEQAATDAGDVTDGERVSALLSGHPLYVIYTSGSTGLPKGVVVTHASVGAYL 3260
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER 194
+ R ++ + ++L F +V ++ PL+ G + + + T +
Sbjct: 3261 R-RGRNAYRGAADGLGHVHSSLAFDLTVTVLFTPLVSGGCVTLGDLDDTANG-------- 3311
Query: 195 LVLVPTLLRSILMYLAL-GPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L T L++ +L L G R L + GE L+ A + + + N
Sbjct: 3312 --LGATFLKATPSHLPLLGQLDRVLAPDATLLLGGEALT---AGALHHWRTHHPHTTVIN 3366
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE+ + Y + L P +PIGRP +++LD L T GE++VA
Sbjct: 3367 AYGPTELTVNCAEYRIPPGHCLPDGP-VPIGRPFTGHHLFVLDPALRLTPPDTIGELYVA 3425
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKI 370
G LA GY+G A RF P + E R+YRTGD G + + GR D QVKI
Sbjct: 3426 GDGLARGYLGRPDLTAERFVACPFRSPGE--RMYRTGDLARWRSDGTLEFIGRADDQVKI 3483
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGKLR 429
RG R++L EVE A+A P V + + + G+ ++ +VT + P +SA + +
Sbjct: 3484 RGFRIELGEVEAAVAAHPHVARAIAVVREDRPGDQRLVAYVTGSDPSGLSSA--VTDTVA 3541
Query: 430 SALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
L YM+P V+ ++ IPL NGKVDR L
Sbjct: 3542 GRLPAYMVPSAVVVLDQIPLTPNGKVDRAAL 3572
>UniRef50_Q08MM0 Cluster: Linear gramicidin synthetase subunit B;
n=1; Stigmatella aurantiaca DW4/3-1|Rep: Linear
gramicidin synthetase subunit B - Stigmatella aurantiaca
DW4/3-1
Length = 746
Score = 196 bits (477), Expect = 2e-48
Identities = 165/583 (28%), Positives = 266/583 (45%), Gaps = 45/583 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A++ KAG Y+ ++P P R+ ++LKD+ +V+ + + + G E
Sbjct: 190 VEAMVGVVKAGCTYLALDPKLPAERLEYMLKDSGTRVVV-TQAEWKGLAEGEGRDVVVLE 248
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E A A A P++ +++ ++A V+YTSGSTG PKGV +++ + RL +
Sbjct: 249 EGAFAAEGGWA--PVE------VSAQAVAYVMYTSGSTGRPKGVAVTHQGVV-RLVRESN 299
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL-- 197
+S + W T + F S E+WG LL+G L++ + L ++ RL+
Sbjct: 300 YAAFSPDDVFLHWNTMM-FDASTFEVWGALLNGARLVV----SPPGLPSLADVARLIAEQ 354
Query: 198 -VPTLLRSILMYLALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
V T+L + ++ L LR LK + G+ + A +L N Y
Sbjct: 355 GVNTVLATAALFQQLVDHQLEGLRPLKNLLAGGDAMPPVQAKRLLDTLPKT---RLINAY 411
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T + L+ D +P+G PLD +Y+LDEE+ P + GE++ G
Sbjct: 412 GPTENAVITTCHTLQPG--YDARTRVPLGVPLDGTDVYVLDEEMQPVPEGVVGELYTGGD 469
Query: 316 NLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
LA GYVG A +F NP+ Q QRLYRTGD G++ + GR D QVK+RG
Sbjct: 470 GLARGYVGRPELTAEKFVPNPYGKQAG-QRLYRTGDLARWRGDGSLEFVGRADTQVKVRG 528
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R+++ EVE AL P V V+ G ++GFV G + + G L L
Sbjct: 529 FRIEIGEVEGALESHPEVKAAAVVVQGEGAEGKRLVGFV-VGGGRKVEVGEVRGYLEKRL 587
Query: 433 THYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P ++EVE +PL NGKVDR+ LL + D
Sbjct: 588 PEYMVPSLLVEVEKLPLTGNGKVDRKALLAQVSEQGAGASSNYVAPRD---------ETE 638
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGAST 550
+LG RG + + F+E GG+SL + + ++++ G + I + T
Sbjct: 639 QKLAKLWEELLG---RGRVGIHDDFFEAGGHSLLATRLVARVQETFGVTLPIRTLFESRT 695
Query: 551 LGEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMVESS 593
+ L++ + P A + + + RD H+ ++ + SS
Sbjct: 696 VAS-LARAVSRPEQAASAPRSEIKRI-SRDSHRIKLSQLKPSS 736
>UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide synthetase;
n=2; Bradyrhizobiaceae|Rep: Probable non-ribosomal
peptide synthetase - Nitrobacter sp. Nb-311A
Length = 3272
Score = 196 bits (477), Expect = 2e-48
Identities = 165/560 (29%), Positives = 261/560 (46%), Gaps = 45/560 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGAAYVP++P +P R+ IL + +++ A ES V
Sbjct: 1204 VVTLLGVLKAGAAYVPLDPKWPLERVRRILNEGHIEILL----AAAEKLTESHVLDCVVI 1259
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW-WQF 138
+ E T+ + + + P + A V+YTSGSTG PKGV + + A+ N + +
Sbjct: 1260 DANAETTNQAISDSPPETVIHPAQT---AYVIYTSGSTGTPKGVAVPHGALANYVQAFLQ 1316
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
R P S + V A +V ++G L G L +LS E DP E V
Sbjct: 1317 RLQPQSSASMAMVSTVAADLGHTV--LFGALASGTTLNLLSPEAVLDPDAFAQAVGEEKV 1374
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V ++ S L L S L + V GE L E + ++ N YG
Sbjct: 1375 GVLKIVPSHLRGLLQARRSADLLPCETLVLGGEACDAMLLDEVRRL---RPHCRIINHYG 1431
Query: 257 STEV-MGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE +G VT+ + + +PIG PL N +++LD L+ GE+++ GA
Sbjct: 1432 PTETTVGVVTHECVS----VHKNEPVPIGLPLANLRVHVLDNSLNEVPIGVTGELYIGGA 1487
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRG 372
+A GY G G A +F +P + RLYRTGD + G +++ GR+D Q+K+RG
Sbjct: 1488 GVARGYRGAAGLTAEQFVPDPFGRAGD--RLYRTGDRVRCDRAGRLIFIGRSDDQIKLRG 1545
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLD--RGNPEILGFVTTKPGARTSAQHIEGKLRS 430
+RV+ EV RAL +PG++ VV+ +D G E++ + G A+ ++ +L +
Sbjct: 1546 YRVEPDEVGRALKALPGINDAVVIARSIDGQAGRQELVAYCVPGDGVTLEAEAVKRQLSA 1605
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
+ YM+P +I +E +PL NGK+DR+ L + + + AE A D + +
Sbjct: 1606 IVPDYMVPSHMIVLERLPLTSNGKIDRKALPETAGSAVLSTYAEPAGDTEATIAEVWR-- 1663
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
VLGR G F+ELGG+S+ S+ + +LR RG V G
Sbjct: 1664 ----------EVLGRERVGR---NDNFFELGGDSILSLQIVARLRKRGVRVTPKQIFGQQ 1710
Query: 550 TLGEV--LSKMSTDPNGGAD 567
T+ + ++ ++TD G +
Sbjct: 1711 TIASLAAVAVVTTDSVAGKE 1730
Score = 177 bits (431), Expect = 9e-43
Identities = 151/459 (32%), Positives = 221/459 (48%), Gaps = 33/459 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T++ALLA KAGAAY+P++P +P R+ H+L+D+ LV+ + S+ + +
Sbjct: 2731 TMVALLAVLKAGAAYLPLDPDYPAERLVHMLRDSGARLVLTESEQLKSL--SPVLDEIAV 2788
Query: 79 EELAQEATSHSADEPMDAETL-APLTSDSIAIVLYTSGSTGIPKGVRLSYSAI---CNRL 134
E L + S A E D L + DS+A V+YTSGSTG PKGV +++ + C +
Sbjct: 2789 ETLCIDRPSLFAGE--DTGNLNIEIHPDSLAYVIYTSGSTGTPKGVAVAHGPLAMHCEAI 2846
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRETTRDPQKLVNIE 193
+R P D E ++TA D E W PL+ G +L++ SR + IE
Sbjct: 2847 SRLYRMTP-RDRE----FQTASINFDIAHERWLAPLMAGGSLVLPSRPGLLIDDLVYEIE 2901
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVC--SGETLSKELASEFFKYFGNEDGYKL 251
R + L + R+L + C GE S E + + D L
Sbjct: 2902 RSSVTTIFLPPAYADQLSAALRQSGRKLSIRACIVGGEAWS-ETGIKAVR--ETVDADLL 2958
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYP--TIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
N YG TE + T +V+ D+ L P T PIGRP+ Y+LD +L+ GE
Sbjct: 2959 INAYGPTETVIAPTAWVV---DEATLQPGQTAPIGRPVGARTAYILDADLNVVPAGVTGE 3015
Query: 310 VWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
+++ GA LA GY+ A RF +P + RLYRTGD G + Y GR D
Sbjct: 3016 LFIGGAGLARGYLNRSAMTAERFIPDPFGANGD--RLYRTGDLARWRDDGVIDYVGRADQ 3073
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVKIRG R++L E+E L + GV V+ G ++ + + P +A +
Sbjct: 3074 QVKIRGFRIELGEIEACLIEQRGVRAAAVVAQDSKTGR-HLVAYASGDPTLDGAA--LRD 3130
Query: 427 KLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYE 464
L + L YM+P I V E +PL NGK+DR+ L K +E
Sbjct: 3131 ALAAVLPDYMVPATIVVLEQLPLSRNGKIDRKALPKPHE 3169
Score = 58.0 bits (134), Expect = 9e-07
Identities = 67/283 (23%), Positives = 115/283 (40%), Gaps = 18/283 (6%)
Query: 281 IPIGRPLDNCAIYLLDEELSPTRD-SEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQP 339
+ GRP + A ++ + S + E GE+WV G ++ GY A R +
Sbjct: 382 VACGRPPADHATRIMRVDGSAAAEMDEVGEIWVTGPSVTLGYWNNPDATRQV----FVER 437
Query: 340 EFQRLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERAL-AQVPGVDKCVVLCY 398
+ R RTGD G + GA++ AGR + +RG + +VE+A+ A V V + V +
Sbjct: 438 DGARWLRTGDLGFIRDGALVVAGRLKDVLIVRGQNIYPTDVEQAVEADVESVRRGRVAAF 497
Query: 399 GLDRGNPEILGF-------VTTKPGARTSAQHI-EGKLRSALTHYMMPQVIEVESIPLLV 450
++ E +G V A+ I + LR A + + ++ ++PL
Sbjct: 498 AVEADGQEGIGVAAEFSRAVLKGEDPEVLAEAIGQAVLRQAQEYPAVIVLLNPRAMPLTT 557
Query: 451 NGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAA-RGT 509
+GK+ R +N D+ + + V + A
Sbjct: 558 SGKLQRSACAARL--ASNTLDSFMVFERGRRRDGAPLTAPVTDTERAVSLIWCDALDLKA 615
Query: 510 LSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTL 551
+ F+ LGGNSL + + +R+R G +E+ F A TL
Sbjct: 616 VHCEDDFFVLGGNSLKAGQVASAIRERFGVELELRSFFDAPTL 658
Score = 41.9 bits (94), Expect = 0.064
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 32 AYVPMEPSFPQ-GRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELAQEATSHSA 90
AY P E S GR+ IL+DA P ++ + E+ P + ++ A
Sbjct: 109 AYPPEESSARYAGRLNGILRDAAPRFILVESGL--CSLVEAAFPELTNVQII--AVDSLL 164
Query: 91 DEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSY 127
EP L +D++A + YTSGST PKGV +S+
Sbjct: 165 TEPAADWRETKLATDAVAFLQYTSGSTSQPKGVCVSH 201
>UniRef50_A3KFG6 Cluster: PstD protein; n=1; Actinoplanes
friuliensis|Rep: PstD protein - Actinoplanes friuliensis
Length = 2370
Score = 196 bits (477), Expect = 2e-48
Identities = 154/449 (34%), Positives = 222/449 (49%), Gaps = 26/449 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ +LAT KAGAAY+P++P +P RI +L DA P +++ + F + E
Sbjct: 1578 VTTMLATLKAGAAYLPVDPEYPPARIRAMLDDAAPDVIVTSRDL-AARFPDDRT--VVLE 1634
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + + + DA+ A LT A V+YTSGSTG PKG+ + A N L W R
Sbjct: 1635 PGALDG--FAGTDLTDADRTAALTPAHPAYVIYTSGSTGRPKGITMPAGATANLLEWHAR 1692
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P + + TA++F SV E+ +L GR L++ + RDP L R +
Sbjct: 1693 ELPGRPGARVAQF-TAVSFDVSVQEMLSAVLTGRTLVVCDEDVRRDPVALTRWLRDSRIQ 1751
Query: 200 TLLRSILMYLALGPASRP----LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
L L+ A+ A+ L L V +GE L+ A ++ G +L N Y
Sbjct: 1752 ELYAPNLVVDAVCEAATTRGITLPELTDLVQAGEALTLHPAVR--RFHEQHPGCRLHNHY 1809
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
G E VT Y L ++++ +P T PIG P+ N A+ +LD L P PGE+++AG
Sbjct: 1810 GPAETHV-VTAYRLP--ERVEQWPATAPIGAPIANSAMRVLDPWLRPVPPGVPGELYIAG 1866
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
ANLA GY+ RF +P R+YRTGD + G + Y GRTD QVKIR
Sbjct: 1867 ANLARGYLNRPALTGQRFVPDPLGAPG--TRMYRTGDLASWDGDGNLRYLGRTDDQVKIR 1924
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G RV+ EVE L +PGV + V G+ ++ +V P T+A H E L
Sbjct: 1925 GFRVEPGEVEAVLTTLPGVTRAAVTVREDRPGDKRLIAYVV--PAQDTAALHRE--LTGR 1980
Query: 432 LTHYMMPQVI-EVESIPLLVNGKVDRQGL 459
L +++P VI ++ +PL NGK+DR L
Sbjct: 1981 LPAHLVPAVIVGLDELPLTPNGKLDRAAL 2009
Score = 136 bits (328), Expect = 3e-30
Identities = 126/449 (28%), Positives = 195/449 (43%), Gaps = 32/449 (7%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
S I+ALL KAG AY+P+ P P R+ ++ D +++ ADP+ +
Sbjct: 522 SLIVALLGILKAGGAYLPLHPGDPDDRMRTVVADTGAPIIL----ADPANAARAA----- 572
Query: 78 FEELAQEATSHSADE--PMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
L SA E P+ L+P ++A ++YTSGSTG+PKGV +++ +
Sbjct: 573 --GLGPRVVDPSATEGGPVPEPALSP---GALAYLIYTSGSTGVPKGVAVTHHNVLELAA 627
Query: 136 WQ-FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER 194
FRT + E + + + F S E+W PLL G ++ Q +
Sbjct: 628 DSAFRTGAH---ERVLI-HSPQAFDASAYELWVPLLSGGTAVVAPPGKLDVAQLGKTLAE 683
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ L S L L A L ++ G+ + A+ + +
Sbjct: 684 HAVTALWLTSGLFQLVADEAPESLAGVREVWTGGDVVP---AASVRAVLDACPDVTVVDG 740
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE + L + +PIG LDN + +LD L P PGE+++ G
Sbjct: 741 YGPTETTTFAVRHRLAPGTPVPA--EVPIGTALDNTDLRVLDAALRPVPPGVPGELYLGG 798
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIR 371
+ GY A RF +P+ +P RLYRTGD + VL Y GR D QVKIR
Sbjct: 799 TGVGRGYHHRPALTAARFAADPYG-EPG-ARLYRTGDLVRWTETGVLEYLGRADHQVKIR 856
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++ E+E LA+ V + VV + G+ + ++ G + +
Sbjct: 857 GFRIETGEIEAVLARHDEVAQAVVTVWEPAPGDKRLAAYLVGARGGTLDTAGVRAHAEAV 916
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++++PL NGKVDR L
Sbjct: 917 LPGYMIPAAFVVLDTLPLTGNGKVDRARL 945
>UniRef50_Q0SEB1 Cluster: Non-ribosomal peptide synthetase; n=2;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Rhodococcus sp. (strain RHA1)
Length = 2366
Score = 195 bits (476), Expect = 3e-48
Identities = 156/453 (34%), Positives = 228/453 (50%), Gaps = 40/453 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA ++GA Y+P++PS P R IL+DA+PSL I SAD +P E
Sbjct: 509 IVAVLAILRSGATYLPIDPSSPAERARFILRDAQPSLGI--GSADLL----GDLP--RVE 560
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + ++ S D + A D IA V+YTSGSTG+PKGV + + + RL+ R
Sbjct: 561 EDSAQSASGELDNAVQA--------DDIAYVIYTSGSTGVPKGVPIPHRNVM-RLFDVSR 611
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERL 195
+ ++ +E+ C W + F SV EIWG LLHG L+ + T P L ++
Sbjct: 612 EW-FTFTEDDC-WPLLHSYAFDFSVWEIWGALLHGGRLVTVDEATLTSPADLAGLLVDEG 669
Query: 196 VLVPTLLRSILMYL--ALGPASRPLR-RLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
V V S +L AL A R RL+ V GE L + +F G ++G +L
Sbjct: 670 VTVLNQTPSAFGHLVDALVRADSFDRLRLRYVVFGGEALDPAVLRAWFAATGPDEGAELV 729
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE VT + +D +D IG PL + Y+L L P GE++V
Sbjct: 730 NMYGITETTVHVTATKVTAADVVD------IGVPLGDLRTYVLGPGLRPVPPGVTGEIYV 783
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
+G L+ GY+G + RF +P A P R+YRTGD G + Y GR D Q++
Sbjct: 784 SGPGLSPGYLGRPDLTSGRFVADPFA--PGGTRMYRTGDLARYDATGTLHYHGRIDDQIQ 841
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA--QHIEGK 427
+RG+RV+L E+ A+ VP V V + G+ I+G+V +PG A + +
Sbjct: 842 LRGYRVELGEIGAAMTAVPDVQAAVATAHEQAGGDQRIVGYVVPRPGGEHDAVEEQVRAH 901
Query: 428 LRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
L +L YM P ++ ++ +PL NGKVD+ L
Sbjct: 902 LVRSLPGYMTPSALVMLDRLPLTHNGKVDKDAL 934
Score = 162 bits (394), Expect = 3e-38
Identities = 130/449 (28%), Positives = 209/449 (46%), Gaps = 25/449 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFK-ESGVPFASF 78
I+++LA K+GAAY+P++P++P RI H+L D P ++ P + VP
Sbjct: 1563 IISVLAVLKSGAAYLPVDPTYPADRIAHMLADGAPVAILTSSVGVPDRTPLGTDVPILDL 1622
Query: 79 EE--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
++ L + P DA+ PL D A ++YTSGSTG+PKGV + + I + L
Sbjct: 1623 DDPGLQSLLDTQPVTAPTDADRSRPLKLDDAAYLIYTSGSTGVPKGVVVPHRGIADLLSL 1682
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEI-WGPLLHGRALLILSRETTRDP-QKLVNIER 194
Q D + ++++F + +I WG L G L+++ + R P + L +
Sbjct: 1683 QSDVIGM-DHTTRALHFSSISFDLAFWQIMWGVLSGGT--LVVATDADRIPGEPLARVIN 1739
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
V + + A P P+ + E L+ +L + G +L N
Sbjct: 1740 EHDV-NFVGVPPSFAAAFPPEHPIPDGVDLMLGAEKLTPQLIERY------APGRRLFNA 1792
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE + T ++E + +PIG Y+LD L P GE+++AG
Sbjct: 1793 YGPTECTVNATLALVEPGHE----GPVPIGVVDPGKHAYVLDHALRPVPPGVSGELYLAG 1848
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIR 371
++ GY A RF +P A R+YRT D + G + + GR D+QVK+R
Sbjct: 1849 DSVTRGYRNQSPKTAERFIADPFAVPGS--RMYRTSDVVWWGRDGQIYFTGRADSQVKVR 1906
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E L+ P V+ VV+ G+ ++ + T+ PG R + + S
Sbjct: 1907 GFRIELNEIEAVLSGDPDVEHIVVVVREDRPGDQRLVAYATSVPGGRIDPDQLHRRAASR 1966
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P I V+ P L NGK+D+ L
Sbjct: 1967 LPDYMIPAAFIAVDEFPTLPNGKLDQTSL 1995
>UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Myxococcus xanthus (strain DK 1622)
Length = 11939
Score = 195 bits (476), Expect = 3e-48
Identities = 165/561 (29%), Positives = 255/561 (45%), Gaps = 42/561 (7%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDS-ADPSMFKESGVPFA 76
S ++ L KAG AYVP++ +FP RI +L DA +++ + A+ + GV
Sbjct: 4793 SAVVGLWGILKAGGAYVPLDVTFPVERIRSVLSDAGAQVLVTQAALAEVLRWGAGGVVRL 4852
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ + S EP + AP +++A V++TSGSTG PKGV + + + + +
Sbjct: 4853 DADASSLLERSERNPEP----SAAP---ENLAYVIFTSGSTGRPKGVAIEHRQLVHYVKG 4905
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-ER- 194
+S T + ++ L G AL ++SRE DP L + ER
Sbjct: 4906 VSCRLDLPESASFASVSTLAADLGHTA-VFPTLCQGGALHLVSRECASDPSALAELFERE 4964
Query: 195 ----LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
L +VP L+++L A G R L R +L V G+ L + +
Sbjct: 4965 AVDCLKIVPAHLQALL---ASGNPERVLPRQRL-VLGGDVSDWALMDRVHEL---SPDLE 5017
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
+ N YG +E V +E Q + ++P+GRP+ N +Y+LD L P PGE+
Sbjct: 5018 VFNHYGPSETTVGVLTLQVERGPQGRVSASVPLGRPIPNARVYVLDAYLRPVPVGVPGEL 5077
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQ 367
+ G + GY+G A RF + +A P R+YRTGD L+ G V + GRTD Q
Sbjct: 5078 CIGGRTVGRGYLGRVDLTAERFVPDAYAEDPG-ARMYRTGDRARLLADGRVEFLGRTDDQ 5136
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
+K+RG+RV++ EVE AL + P V + VV+ + ++G+ KPG +
Sbjct: 5137 LKVRGYRVEMGEVEAALERHPSVRESVVVAHESGTDGKRLVGYAVPKPGHTLEVDALRDF 5196
Query: 428 LRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L L YM+PQ + V E++PL NGKVDR L A +D
Sbjct: 5197 LGQTLPDYMVPQALVVLEALPLTPNGKVDRNAL-----------PAPDFQSVDAEAFVAP 5245
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDF 545
VLG G + SGF+ELGG+SL + I+++R G + + D
Sbjct: 5246 RTATEELVAGLFSEVLGLDRVG---IHSGFFELGGHSLLATQAISRIRGAFGVELPLRDL 5302
Query: 546 LGASTLGEVLSKMSTDPNGGA 566
A T+ + ++ GA
Sbjct: 5303 FEAPTVAALAERVDRWVRAGA 5323
Score = 194 bits (472), Expect = 1e-47
Identities = 153/551 (27%), Positives = 259/551 (47%), Gaps = 38/551 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++LL KAG YVP++ S+P R+ + +++ ++++ + + +
Sbjct: 3738 VVSLLGILKAGGVYVPLDASYPLERLAWMKQESGVAVLVAQEKLADEVAAGGELVVCVDT 3797
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + H P A + ++A V++TSGSTG PKGV + + A+ +
Sbjct: 3798 EWDSQIAHHPQTTPS-----ANVCGGNLAYVMFTSGSTGKPKGVGVPHRAVSRLVLGT-- 3850
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + EE+ + ++F S E+WG LLHG L++ T + +E +
Sbjct: 3851 DFAHFGPEEVWLQLAPISFDASTLEVWGALLHGAKLVVYPAGTPSLEELGRKLESSGVTS 3910
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + L ++ + G+ L E G L N YG TE
Sbjct: 3911 LWLTAALFEQMQARQPKALANVRQLLAGGDALPVSRVKERLAAGG-----LLFNGYGPTE 3965
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ Y +E +++ + ++ IGRP+ N Y+LD + P PGE++V G LA
Sbjct: 3966 NTTFSSTYRMEKPEEVGV--SVSIGRPVKNTVAYVLDAGMRPVPVGVPGELYVGGDGLAV 4023
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GYVG A RF +P E +RLYRTGD L G + + GR D QVK+RG+R++
Sbjct: 4024 GYVGRPELTAERFVPSPFG---EGERLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIE 4080
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EVE ALAQ GV++ VV+ ++ +VT + GA + ++ L YM
Sbjct: 4081 LGEVEAALAQHGGVNEAVVVAREDGGEGKRLVAYVTAQEGASLDTGALRSHMKQRLPEYM 4140
Query: 437 MPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXX 495
+P + +E++PL NGKVDR+ L DA+ +
Sbjct: 4141 VPSAYVVLEALPLTPNGKVDRKAL--------PVPDAQGPK----AAHFEAPRTATEEKL 4188
Query: 496 XTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVE--ISDFLGASTLGE 553
++ A + R +S+ F+ELGG+SL + ++++R+ ++VE + D A T+ +
Sbjct: 4189 ASIFAEVLNVER--VSVDEDFFELGGHSLLATQLVSRVRE-AFHVELPLRDVFEAPTVEK 4245
Query: 554 VLSKMSTDPNG 564
+ ++ T+PNG
Sbjct: 4246 LAQRLETEPNG 4256
Score = 192 bits (467), Expect = 4e-47
Identities = 162/552 (29%), Positives = 258/552 (46%), Gaps = 40/552 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ALL KAG AYVP++P +P R+ ++L+D+ +V+ + + G +
Sbjct: 553 LAALLGVLKAGGAYVPLDPEYPAERLGYMLEDSGARVVVARREYREKLGEAPGRVWLDVA 612
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L +A E +E A + ++ A VLYTSGSTG PKGV + + ++ + + +++
Sbjct: 613 SLTPDA------EGKTSEPTAVVPPEAAAYVLYTSGSTGRPKGVVVQHRSLVSFIRAEWQ 666
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ------KLVNIE 193
P + + + ++++ S EI+ L G L++ + E P+ + I
Sbjct: 667 VCPVEPGDRVLQF-ASISWDTSAEEIYPCLTRGGTLVLRTPEMLDVPEVFLARCEAAGIT 725
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+L L + L G A P LK V GE S++ + G+ L N
Sbjct: 726 QLNLPTAFWHEVTASLDEGKARLP-SGLKWVVIGGERAVPARVSQWRQRVGH--AVPLLN 782
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TEV T L +D D + IGRPL N IY+LD EL P GE++V
Sbjct: 783 TYGLTEVTAVATAVDLT-TDTEDSGREVAIGRPLTNVRIYVLDGELEPVPAGVVGELYVG 841
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKI 370
G +A GY+G A RF P Q + RLYRTGD + VL Y GR D+QVK+
Sbjct: 842 GEGVARGYLGRPELTAERFVPAP---QGDGARLYRTGDKARWRRDGVLEYLGRGDSQVKV 898
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RGHR++ EVE AL PGV + +V+ G+ ++ +V + G + L S
Sbjct: 899 RGHRIEPGEVESALLGQPGVREVLVVVREDAPGDKRLVAYVVPRDGRLLEGGEVRAGLES 958
Query: 431 ALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L +M+PQ V+ +E +PLL NGKVDR+ L + +A VA
Sbjct: 959 RLPRFMVPQAVVVLERLPLLPNGKVDRKALPAPEAVRESRKEAHVAPRTPVEQMLAGFWA 1018
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVE--ISDFLG 547
T+ L F+E+GG+SL ++ + ++R+ + V+ + D
Sbjct: 1019 EVLRLE-------------TVGLHDNFFEVGGHSLLAMQLVARVRE-SFRVDLPLRDVFE 1064
Query: 548 ASTLGEVLSKMS 559
++T+ + ++S
Sbjct: 1065 SATVAALAERIS 1076
Score = 191 bits (466), Expect = 5e-47
Identities = 132/444 (29%), Positives = 216/444 (48%), Gaps = 21/444 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++L KAG YVP++ S+P R+ + ++A ++++ + + S +
Sbjct: 10100 VVSVLGILKAGGVYVPLDASYPLERLAWMKQEAGVAVLVAQEKLADEVATGSELVVCVDT 10159
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + H P A + ++A V++TSGSTG PKGV + + A+ +
Sbjct: 10160 EWDTQIAHHPQTTPS-----ANVGGGNLAYVMFTSGSTGKPKGVGVPHRAVSRLVLGT-- 10212
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + EE+ + ++F S E+WG LLHG L++ T + N+E +
Sbjct: 10213 DFAHFGPEEVWLQLAPISFDASTLEVWGALLHGSRLVVYPAGTPSLEELGRNLESSGVTS 10272
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + L ++ + G+ L E G L N YG TE
Sbjct: 10273 LWLTAALFEQMQARQPKALASVRQLLAGGDALPVSRVKERLAAGG-----VLINGYGPTE 10327
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ Y +E +++ ++ IGRP+ N +Y+LD + P PGE++V G LA
Sbjct: 10328 NTTFSSTYRMESPEEVGA--SVSIGRPVKNTVVYVLDAGMRPVPVGVPGELYVGGDGLAM 10385
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHRVD 376
GYVG A RF NP+ + +RLYRTGD ++ L + GR D QVK+RG+R++
Sbjct: 10386 GYVGRPELTAERFVPNPYG---DGERLYRTGDVVRWLRNGTLEFLGRADTQVKVRGYRIE 10442
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L +VE ALAQ GV + VV+ ++ +VT + GA A + ++ L YM
Sbjct: 10443 LGDVEAALAQHSGVSEAVVVAREDGGEGKRLVAYVTAQEGATLDAGALRSHMKQRLPEYM 10502
Query: 437 MPQV-IEVESIPLLVNGKVDRQGL 459
+P + +E++PL NGKVDR+ L
Sbjct: 10503 VPSAYVVLEALPLTPNGKVDRKAL 10526
Score = 190 bits (463), Expect = 1e-46
Identities = 177/577 (30%), Positives = 263/577 (45%), Gaps = 54/577 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA +AG A+VP+EP P+ R+ IL+DA P+ V+ A + + +P FE
Sbjct: 2678 VVGLLAILEAGGAWVPLEPDAPRERLARILEDAAPA-VLLTQRALRDLVPATSMPVVVFE 2736
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + + A +D+ A VL+TSGSTG PKGV +S+ A+ W
Sbjct: 2737 DDLGSVAAGAWE--------ASAVADNAAYVLFTSGSTGRPKGVLVSHRALARHTAWFIA 2788
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
+ + + K + F +V E+ L+ G L+I D + L+ +ER
Sbjct: 2789 ALKLGTGDRV-LQKASAGFDAAVPELLATLVSGARLVIAPPAAESDTEVLLAALERQQVT 2847
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L LVP+ LR +L + + A+ L++ V GE L EL + + + + N
Sbjct: 2848 MLQLVPSQLRVLLAHEDVARAAG----LRVLVSGGEALPVELVHQARERLPST---LIIN 2900
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D T ++ G D L P PIGRP+ N Y+LD + P PGE++V
Sbjct: 2901 AYGPTETTVDATAWL--GGD-LSEGPFAPIGRPIANTQAYVLDAQGQPVPVGVPGELFVG 2957
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKI 370
G LA GYVG A RF + P RLYRTGD G L + GR D QVK+
Sbjct: 2958 GDGLARGYVGRPDLTAERFVPDALGRMPG-ARLYRTGDQVRWRSGGSLEFLGRVDTQVKV 3016
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT-KPGARTSAQHIEGKLR 429
RGHRV+ EVE LA+ P V VV+ ++ +V A + L
Sbjct: 3017 RGHRVEPGEVEVVLAEHPAVHVAVVVSRKDASNETRLVAYVVPGDASGAVDATALRAFLA 3076
Query: 430 SALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
L M+P + +ES+PLL +GKVDR+ L A D+D S
Sbjct: 3077 ERLPSAMVPSWFVVLESLPLLPSGKVDRKAL--------------PAPDVDVSERQYVAP 3122
Query: 489 XXXXXXXXT--VGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEIS--D 544
VLG G + GF+ELGG+SL + ++++R + VE++ +
Sbjct: 3123 RTPTEELLCGFFSRVLGVERVG---IHDGFFELGGHSLLATQLVSRVRS-AFRVELALRE 3178
Query: 545 FLGASTLGEVLSKMSTDPNGGADSKEATFTAVPMRDE 581
A T+ E+ ++ GA+ AVP E
Sbjct: 3179 LFEAPTVAELARRIDQAKRSGAEMPMLRSPAVPRARE 3215
Score = 186 bits (453), Expect = 2e-45
Identities = 157/549 (28%), Positives = 257/549 (46%), Gaps = 40/549 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+L KAG AYVP++P++P R+ +++D++P +++ + ++ P
Sbjct: 11159 LIAVLGILKAGGAYVPLDPAYPSQRLAFMIEDSQPRVLVGQRALLDAL------PHGDVA 11212
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA + + E A L D +A VL+TSGSTG PKGV L++ + L W R
Sbjct: 11213 RLALDDANGLVAEAEAAPVLRS-APDHLAYVLFTSGSTGRPKGVALAHRSAVAFLRWTTR 11271
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F SD + T+L F SV E++ PL+ G +++I S + L R+ L+
Sbjct: 11272 AFS-SDELAGVLASTSLNFDLSVFEMFAPLIRGGSVVIASNAL--ELPSLPGARRVTLIN 11328
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
T+ ++ + +R + L +GE L++ L + ++ N YG TE
Sbjct: 11329 TVPSAMAELVRAQTVPDSVRTVNL---AGEPLAQSLVESIHQSAPGVQ--RVLNLYGPTE 11383
Query: 260 VMGDVTYYVLEGSDQ-LDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
D TY + + PT+ GRP++ Y+LD P GE+++ GA LA
Sbjct: 11384 ---DTTYSTWTVAPRGATREPTV--GRPIEGTRAYVLDALGQPVPQGVAGELYLGGAGLA 11438
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GYV A RF + + QP RLYRTGD L G + Y GR D QVK+RG R+
Sbjct: 11439 RGYVDRPELTAERFVPDAFSPQPG-ARLYRTGDSARWLPDGVLQYLGRIDQQVKVRGFRI 11497
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E L + P V + VV+ ++ ++ + A + ++ L +
Sbjct: 11498 ELGEIEAVLRRHPDVREAVVVVRDDGSEGRRLVAYIVPQSDRVPDATALRRFVKEGLPDF 11557
Query: 436 MMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P V+ V S+PL NGKVDR+ L A A+ + +
Sbjct: 11558 MVPSVVMVLASLPLTPNGKVDRKAL-----------PAPDALRPESTRAYVAPRDALELQ 11606
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLGE 553
+ L G + + S F+ELGG+SL ++ ++ +R+R G + + A TL E
Sbjct: 11607 LTRIWEEL--LGTGPIGIHSDFFELGGHSLLAMRMVSLIRERLGRSLPVVSLFQAGTLAE 11664
Query: 554 VLSKMSTDP 562
+ S++ P
Sbjct: 11665 LASRLRHAP 11673
Score = 186 bits (452), Expect = 3e-45
Identities = 132/444 (29%), Positives = 214/444 (48%), Gaps = 20/444 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++L KAG YVP++ S+P R+T + ++A +L++ SM +
Sbjct: 6920 VVSVLGILKAGGVYVPLDASYPLKRLTWMKQEASVTLLVGQQKLLESMMLSDTESSVCVD 6979
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + +P ++ + + +A V++TSGSTG PKGV + + A+ +
Sbjct: 6980 T---EWDAQIVHQP-ESNLRSSVAGGHLAYVMFTSGSTGKPKGVGVPHRAVSRLVLGT-- 7033
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + EE+ + +F S E+WG LLHG L++ T + +E +
Sbjct: 7034 DFAHFGPEEVWLQLAPTSFDASTLEVWGALLHGAKLVVYPAGTPSLEELGRKLESSGVTS 7093
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + L ++ + G+ L E G L N YG TE
Sbjct: 7094 LWLTAALFEQMQARQPKALASVRQLLAGGDALPVLRVKERLAAGG-----LLINGYGPTE 7148
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ Y +E +++ ++ IGRP+ N +Y+LD + P PGE++V G LA
Sbjct: 7149 NTTFSSTYRMERPEEVGA--SVSIGRPVKNTVVYVLDAGMRPVPVGVPGELYVGGDGLAM 7206
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GYVG A RF NP+ E +RLYRTGD L G + + GR D QVK+RG+R++
Sbjct: 7207 GYVGRPELTAERFVPNPYG---EGERLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIE 7263
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EVE ALAQ GV++ V + ++ +VT + G + + ++ L YM
Sbjct: 7264 LGEVEAALAQHGGVNEAVAVTREDGGEGKRLVAYVTARTGTSLESSALRSHMKQRLPEYM 7323
Query: 437 MPQV-IEVESIPLLVNGKVDRQGL 459
+P + +E++PL NGKVDR+ L
Sbjct: 7324 VPSAYVVLEALPLTPNGKVDRKAL 7347
Score = 186 bits (452), Expect = 3e-45
Identities = 132/444 (29%), Positives = 213/444 (47%), Gaps = 21/444 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++L KAG YVP++ S+P R+ + +A ++++ + + +
Sbjct: 7982 VVSVLGILKAGGVYVPLDASYPLERLAWMKHEAGVAVLVAQEKLADEVATGGELVVCVDT 8041
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + H P A + ++A V++TSGSTG PKGV + + A+ +
Sbjct: 8042 EWDTQIAHHPQITPS-----ANVGGGNLAYVMFTSGSTGKPKGVGVPHRAVSRLVLGT-- 8094
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + EE+ + ++F S E+WG LLHG L++ T + N+E +
Sbjct: 8095 DFVHFGPEEVWLQLAPISFDASTLEVWGALLHGSRLVVYPAGTPSLEELGRNLESSGVTS 8154
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + L ++ + G+ L E G L N YG TE
Sbjct: 8155 LWLTAALFEQMQARQPKALANVRQLLAGGDALPVLRVEERLAAGG-----LLINGYGPTE 8209
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ Y +E +++ + ++ IGRP+ N Y+LD + P PGE++V G LA
Sbjct: 8210 NTTFSSTYRMEKPEEVGV--SVSIGRPVKNTVAYVLDAGMRPVPVGVPGELYVGGDGLAV 8267
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHRVD 376
GYVG A RF +P E +RLYRTGD ++ L + GR D QVK+RG+R++
Sbjct: 8268 GYVGRPALTAERFVPSPFG---EGERLYRTGDVVRWLRNGTLEFLGRADTQVKVRGYRIE 8324
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EVE ALAQ GV++ VV+ ++ +VT + GA + ++ L YM
Sbjct: 8325 LGEVEAALAQHGGVNEAVVVAREDGNEGKRLVAYVTAQEGASLDTGALRNHVKQRLPEYM 8384
Query: 437 MPQV-IEVESIPLLVNGKVDRQGL 459
+P + +ES+PL NGKVDR+ L
Sbjct: 8385 VPSAYVVLESLPLTPNGKVDRKAL 8408
Score = 186 bits (452), Expect = 3e-45
Identities = 133/444 (29%), Positives = 212/444 (47%), Gaps = 20/444 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++L KAG YVP++ S+P R+ + ++A +L++ SM +
Sbjct: 9040 VVSVLGILKAGGVYVPLDASYPLERLAWMKQEAGVTLLVGQQKLLESMGLNDTESRVCVD 9099
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +H + A + ++A V++TSGSTG PKGV + + A+ +
Sbjct: 9100 TEWETRIAHQ----LQTTPSANVGGGNLAYVMFTSGSTGNPKGVGVPHRAVSRLVLGT-- 9153
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + EE+ + ++F S E+WG LLHG L++ T + +E +
Sbjct: 9154 DFAHFGPEEVWLQLAPISFDASTLEVWGALLHGAKLVVYPAGTPSLEELGRKLESSGVTS 9213
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + L ++ + G+ L E G L N YG TE
Sbjct: 9214 LWLTAALFEQMQARQPKALASVRQLLAGGDALPVLRVKERLAAGG-----VLINGYGPTE 9268
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ Y +E +++ ++ IGRP+ N Y+LD + P PGE++V G LA
Sbjct: 9269 NTTFSSTYRMERPEEVGA--SVSIGRPVKNTVAYVLDMGMRPVPVGVPGELYVGGDGLAV 9326
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GYVG A RF NP+ E +RLYRTGD L G + + GR D QVK+RG+R++
Sbjct: 9327 GYVGRPELTAERFVPNPYG---EGERLYRTGDVVRWLSNGTLEFLGRADTQVKVRGYRIE 9383
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EVE ALAQ GV + VV+ ++ +VT + G + + ++ L YM
Sbjct: 9384 LGEVEAALAQHSGVSEAVVVAREDGGEGKRLVAYVTARTGTSLESSALRSHMKQRLPEYM 9443
Query: 437 MPQV-IEVESIPLLVNGKVDRQGL 459
+P + +ES+PL NGKVDR+ L
Sbjct: 9444 VPSAYVVLESLPLTPNGKVDRKAL 9467
Score = 184 bits (448), Expect = 8e-45
Identities = 135/444 (30%), Positives = 217/444 (48%), Gaps = 21/444 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++L KAG YVP++ S+P R+ + +A +L++ A + E
Sbjct: 1620 VVSVLGILKAGGVYVPLDASYPLERLAWMKAEAGVALLV----AQEKLADEVAAGGELVV 1675
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E + A +P A + + ++A V++TSGSTG PKGV + + A+ +
Sbjct: 1676 CVDTEWDTQIALQPEVAPS-THVGGGNLAYVMFTSGSTGKPKGVGVPHRAVSRLVLGT-- 1732
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + EE+ + ++F S E+WG LLHG L++ T + ++ +
Sbjct: 1733 DFAHFGPEEVWLQLAPISFDASTLEVWGALLHGAKLVVYPAGTPSLEELGRKLKSSGVTS 1792
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + L ++ + G+ L E G L N YG TE
Sbjct: 1793 LWLTAALFEQMQARQPKALDSVRQLLAGGDALPVSRVKERLAAGG-----LLINGYGPTE 1847
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ Y +E +++ ++ IGRP+ N Y+LD + P PGE++V G LA
Sbjct: 1848 NTTFSSTYRMERPEEVGA--SVSIGRPVKNTVAYVLDGVMRPVPVGVPGELYVGGDGLAV 1905
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GYVG A RF NP+ E +RLYRTGD L G + + GR D QVK+RG+R++
Sbjct: 1906 GYVGRPELTAERFVPNPYG---EGERLYRTGDMVRWLGNGTLEFLGRADTQVKVRGYRIE 1962
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EVE ALAQ GV++ VV+ ++ +VT + GA ++ + ++ L YM
Sbjct: 1963 LGEVEAALAQHGGVNEAVVVAREDGGEGKRLVAYVTAQEGAELASSALRSHMKQRLPEYM 2022
Query: 437 MPQV-IEVESIPLLVNGKVDRQGL 459
+P + +ES+PL NGKVDR+ L
Sbjct: 2023 VPSAYVVLESLPLTPNGKVDRKAL 2046
Score = 177 bits (431), Expect = 9e-43
Identities = 150/544 (27%), Positives = 247/544 (45%), Gaps = 36/544 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++L KAG YVP++ S+P R+ + ++A ++++ A + E
Sbjct: 5861 VVSVLGILKAGGVYVPLDASYPLERLAWMKQEAGVAVLV----AQEKLADEVATGGELVV 5916
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E + A +P A + + ++A V++TSGSTG PKGV + + A+ +
Sbjct: 5917 CVDTEWDTQIALQPEVAPS-THVGGGNLAYVMFTSGSTGKPKGVGVPHRAVSRLVLGT-- 5973
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + EE+ + ++F S E+WG LLHG L++ T + +E +
Sbjct: 5974 DFAHFGPEEVWLQLAPISFDASTLEVWGALLHGAKLVVYPAGTPTLEELSRKLESSGVTS 6033
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L + L ++ + G+ L E G L N YG TE
Sbjct: 6034 LWLTAALFEQMQARQPKALASVRQLLAGGDALPVLRVKERLAAGG-----LLINGYGPTE 6088
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ Y +E +++ ++ IGRP+ N Y+LD + P PGE++V G LA
Sbjct: 6089 NTTFSSTYRMERPEEVGA--SVSIGRPVKNTVAYVLDMGMRPVPVGVPGELYVGGDGLAV 6146
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GYVG A RF +P E RLYRTGD L G + + GR D QVK+RG+R++
Sbjct: 6147 GYVGRPELTAERFVPSPFG---EGARLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIE 6203
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EVE ALAQ GV++ V + ++ +VT + G + ++ L YM
Sbjct: 6204 LGEVEAALAQHGGVNEAVAVTREDGSEGKRLVAYVTAQEGVSLETGALRSHMKQRLPEYM 6263
Query: 437 MPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXX 495
+P + +ES+PL NGKVDR+ L A A +
Sbjct: 6264 VPSAYVVLESLPLTPNGKVDRKAL-----------PAPDAQGPKAAHFEAPRTATEQRLA 6312
Query: 496 XTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLGEV 554
VL G L F+ELGG+SL + ++++R+ + + D +ST+G++
Sbjct: 6313 SIFAEVLNVERVG---LEGDFFELGGHSLLATQLVSRVREELQVELPLRDIFESSTVGKL 6369
Query: 555 LSKM 558
++
Sbjct: 6370 AERI 6373
>UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep:
MassB - Pseudomonas fluorescens
Length = 4315
Score = 195 bits (476), Expect = 3e-48
Identities = 165/539 (30%), Positives = 257/539 (47%), Gaps = 50/539 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ L A KAG AYVP++P++P RI ++L D+ P +V+ SA ++ ++ V
Sbjct: 3806 VIGLFAILKAGGAYVPLDPAYPPERIAYMLHDSAP-VVVLAQSATRALLGDAVV-----I 3859
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L H +P+ + LTS A V+YTSGSTG PKGV ++ + NRL W
Sbjct: 3860 DLDHSTWQH---QPVTNPPVPGLTSLHAAYVIYTSGSTGQPKGVINEHAGVVNRLLWMQD 3916
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + + + KT +F SV E + PL G L++ E +DP L + +
Sbjct: 3917 AYGLK-AHDAVLQKTPFSFDVSVWEFFWPLFTGARLVMARPEGHKDPAYLCEVIAAEHIT 3975
Query: 200 TL--LRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
TL + S+L ++LA G S+ + +++ +CSGE L L F + G L N YG
Sbjct: 3976 TLHFVPSMLDVFLAHGDISQAVGLVRV-MCSGEALPGSLVRRFKQQL---PGIGLYNLYG 4031
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE DVT + + D PIG+P+ N +Y+LD +L P GE+++AG
Sbjct: 4032 PTEAAVDVTAWNCARPEVPD---NTPIGKPIANTRLYVLDGQLQPVPLGVAGELFIAGVQ 4088
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ A RF D+P R+YRTGD G L G + Y GR D QVKIRG
Sbjct: 4089 VARGYLNRPELTAERFLDDPFTP----GRMYRTGDLGRYLPDGTLEYLGRNDDQVKIRGL 4144
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E++ L + P V VV+ + ++ + T GA + +L L
Sbjct: 4145 RIELGEIQARLIEHPAVKDAVVVA-----RDQRLVAYYT---GAPADIDSLRAQLLQHLP 4196
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
+M+P + + +++ PL NGK+DR+ L D +V
Sbjct: 4197 DFMVPALFMHLDAWPLSPNGKLDRKAL-----PAPGMDALQV-------REYAAPEGDTE 4244
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
+ A L + R + F+ELGG+SL ++ I +LR G ++ TL
Sbjct: 4245 VLMAQLWAELLKVER--VGRHDNFFELGGHSLLAVSLIGRLRQEGMEADVRGLFEQPTL 4301
Score = 190 bits (462), Expect = 2e-46
Identities = 146/449 (32%), Positives = 222/449 (49%), Gaps = 32/449 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAGA YVP++P++PQ RI + L D+ P V+ AD + + G
Sbjct: 618 IIGLLGILKAGAGYVPIDPAYPQERIAYTLADSRPVAVLVQ--ADTA--QRVGA------ 667
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA+ H P+ L L+ ++A V+YTSGSTG PKGV + + + RL+ +
Sbjct: 668 -LARIDLDHLGPLPISNPRLH-LSPANLAYVIYTSGSTGQPKGVMIEHRQVA-RLFGATQ 724
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VNIE 193
+ + ++ + F SV EIWG L+HG LLI+ + +R P + +
Sbjct: 725 QWFGFNHHDVWALFHSFAFDFSVWEIWGALMHGGQLLIVPQLVSRSPDECYALLCDAQVS 784
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L P+ R ++ S LR++ + GE L + ++ N G +L N
Sbjct: 785 ILNQTPSAFRQLIAAQGNSAQSHSLRQV---IFGGEALEPGMLKPWYARAVNA-GTQLVN 840
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTY LE +D L PIG + + +Y+LD P GE++V
Sbjct: 841 MYGITETTVHVTYRALEAADA-HLVGMSPIGVRIPDLQLYVLDARREPLPLGVVGELYVG 899
Query: 314 GANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKI 370
GA +A GY+ N RF +P AT R+Y+TGD G L+ G+V Y GR D QVK+
Sbjct: 900 GAGVARGYLNREALNAERFVADP-ATG---LRMYKTGDLGRLLADGSVEYLGRNDDQVKV 955
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E++ LA GV VV+ G+ ++ +V + G A + LRS
Sbjct: 956 RGFRIELGEIQAHLATANGVRDAVVIAREDQPGDKRLVAYVIS-DGELNVAALRDHLLRS 1014
Query: 431 ALTHYMMPQVIEVESIPLLVNGKVDRQGL 459
H + + ++++PL NGK+DR+ L
Sbjct: 1015 LAEHMVPSAFVRLDTLPLTTNGKLDRKAL 1043
Score = 160 bits (388), Expect = 2e-37
Identities = 112/363 (30%), Positives = 177/363 (48%), Gaps = 18/363 (4%)
Query: 103 TSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSEEICVWKTALTFVDSV 162
+SDS+A ++YTSGSTG PKGV +++ I +RL ++ + I + + F S
Sbjct: 1750 SSDSVAYIMYTSGSTGTPKGVLVTHRGI-SRLVINNGYADFNPHDRIA-FASNPAFDAST 1807
Query: 163 CEIWGPLLHGRALLILSRETTRDPQKL-VNIERLVLVPTLLRSILMYLALGPASRPLRRL 221
++WG LL+G + ++ T DP ++ ++ Y+ L P + L L
Sbjct: 1808 MDVWGALLNGGQVQVIDHATLLDPLAFGAELKGATVLFVTTALFNQYVQLIPQA--LAGL 1865
Query: 222 KLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEG-SDQLDLYPT 280
++ +C GE + F +L + YG TE T Y + + D +
Sbjct: 1866 RILLCGGERADP---AAFRSLLAQAPALRLVHCYGPTETTTYATTYEVRALASDAD---S 1919
Query: 281 IPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGG--GANRFCDNPHATQ 338
+P+GRP+ N IY+LD +L P GE+ + G +A GY+ A +F +NP Q
Sbjct: 1920 VPVGRPISNTQIYVLDAQLQPVPLGITGEICIGGEGVAKGYLNRAQLTAEKFVNNPFVDQ 1979
Query: 339 PEFQRLYRTGDFGTLVKGAVLYA-GRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLC 397
P +YRTGD G + +L GR D QVKIRG R++L E+E LA G+ + VL
Sbjct: 1980 PG-ALMYRTGDLGRWSEEGLLECLGRNDDQVKIRGFRIELGEIEARLASCAGIQEVAVLA 2038
Query: 398 YGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDR 456
G+ ++ + T GA + L+ L YM+P + + S+PL NGK+DR
Sbjct: 2039 REDVPGDKRLVAYFTW-AGADLGIDQVHAHLQGQLPDYMLPSAYMPLASLPLTNNGKLDR 2097
Query: 457 QGL 459
+ L
Sbjct: 2098 KAL 2100
Score = 149 bits (360), Expect = 4e-34
Identities = 130/447 (29%), Positives = 202/447 (45%), Gaps = 45/447 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAGA YVP++P++P RI ++L+D+ P V+ + S + V
Sbjct: 2751 LVGLLGILKAGAGYVPIDPAYPAERIAYLLQDSAPVAVLAETSTRELL---GSVALVDLH 2807
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A + H+ P L LT +A V+YTSGSTG PKGV + + + N + W
Sbjct: 2808 DPAWQR--HAVSNPQ----LPALTPAHLAYVIYTSGSTGQPKGVMVEHGTVENLVHWHCE 2861
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP-QKLVN--IERLV 196
F + + F E+W L G L + E + +L+ + + +
Sbjct: 2862 AFGLTAVSHTSS-VAGMGFDAMAWEVWPALCVGATLHLPPAEIGNENIDELLAWWLAQPL 2920
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V L + Y P P R+ L + + + F E + + N YG
Sbjct: 2921 DVSFLPTPVAEYAFSLPQQHPTLRILL-----------IGGDRLRQFSQERRFAVVNNYG 2969
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE V+ S ++ + IGRP+ N Y+LD L P GE++V G+
Sbjct: 2970 PTEAT------VVATSGRVRAGQVLHIGRPIANATSYVLDAHLRPVPVGVAGELYVGGSG 3023
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ A RF +P R+YRTGD L G + Y GR D QVK+RG
Sbjct: 3024 VARGYLNRPELTAERFLQDPFNAG----RMYRTGDLVRWLPDGNLEYLGRNDDQVKLRGV 3079
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP-GARTSAQHIEGKLRSAL 432
RV+L E+E LA + G+ + VVL R + F +P T H++ +L AL
Sbjct: 3080 RVELGEIESRLAALDGIREAVVLV----REGRLLAWFTEQRPLQIETLRAHLQAQLPEAL 3135
Query: 433 THYMMPQVIEVESIPLLVNGKVDRQGL 459
+ ++++ +PL NGK+DR+ L
Sbjct: 3136 ---VPVAYMQLDQLPLTANGKLDRKAL 3159
>UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabdus
bovienii|Rep: Peptide synthetase XpsB - Xenorhabdus
bovienii
Length = 3316
Score = 195 bits (475), Expect = 4e-48
Identities = 138/451 (30%), Positives = 226/451 (50%), Gaps = 18/451 (3%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + KAGA+Y+P++P+ P R+ ++L D++P L++ + + +A
Sbjct: 570 VIGFVGILKAGASYIPLDPNHPTERLAYMLSDSQPVLMLTQQHLKARLPVTNIPVWALDS 629
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E Q + + +DA L LTS ++A VLYTSGSTG+PKGV + + + + + QF+
Sbjct: 630 EEHQTCIASQPKDNIDASQLG-LTSQNLAYVLYTSGSTGLPKGVMIEHQNVVHLIHSQFQ 688
Query: 140 TFPYSDSEEICVWKTA-LTFVDSVCEIWGPLLHGRALLILSRETTR--DPQKLVNIER-- 194
+ + CV + A F +SV EI+ G A ++L + + D + + ++
Sbjct: 689 MSKLTPHD--CVLQFASFGFDNSVAEIFPTFAIG-ATVVLRPDHIKVPDTEFITFLQNQG 745
Query: 195 --LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+V +PT + S P +L+ GE + G + +
Sbjct: 746 ITVVDLPTAFWHLWAQEISAGYSWPPEQLRSVAAGGEKAEHRHLVTWLSSPGTQK-CRWL 804
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE + T V++ + L Y IPIGRP+ N IY+LD+ P GE+ +
Sbjct: 805 NTYGPTETTVNATSIVID-KENLCTYEDIPIGRPIANTRIYILDQRGQPVPIGVNGEIHI 863
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
+G+ +A GY+ A RF +P + P R+Y+TGD G L G + Y+GR D QVK
Sbjct: 864 SGSGVARGYLNRSELTAERFIQDPFSDIPG-ARMYKTGDLGRWLPDGTISYSGRNDFQVK 922
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG R++L E+E LA GV VV+ D G+ ++ ++ + GA +A + +L
Sbjct: 923 IRGFRIELGEIEAQLATCAGVKDAVVIVREDDNGDKRLVAYLIPQSGAILNAASLREQLS 982
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + +E+ PL NGK+DR L
Sbjct: 983 VNLADYMLPSAFVTLEAFPLNQNGKIDRPAL 1013
Score = 182 bits (442), Expect = 4e-44
Identities = 152/547 (27%), Positives = 249/547 (45%), Gaps = 36/547 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++L KAGA YVP++P++P R+ +IL D+ P L++ + E +P +
Sbjct: 2747 VISMLGILKAGAGYVPLDPAYPAERLAYILSDSAPKLLLTQQHLQGRLAVED-LPVWRLD 2805
Query: 80 ELAQEAT--SHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ +T D P D+ L L +A ++YTSGSTG+PKGV + + + N + Q
Sbjct: 2806 DADHLSTVAQQPTDNP-DSRRLE-LQPHHLAYIIYTSGSTGLPKGVMIEHRNVVNFTYAQ 2863
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSR-----ETTRDPQKLVNI 192
+ ++ + + +++F +V EI+ L G L++ +TT
Sbjct: 2864 CQVSELKSTDRVLQF-ASVSFDTAVSEIFPTLAVGATLILRPAHIQVPDTTFSDFLREQA 2922
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEF-FKYFGNEDGYKL 251
+V +PT + S L+ GE EL ++ +
Sbjct: 2923 ISIVDLPTAFWHQWVQEMKAGRSGFSSLLRSVTVGGE--KAELRHYLTWQSMPETRNCRW 2980
Query: 252 ANFYGSTEVMGDVTYYVLEG--SDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
+ YG TE T L+ +D T+ IGRP+ N IY+LD P GE
Sbjct: 2981 IDSYGPTETTVITTALALDNPTADASRAMETLSIGRPIANTRIYILDTRGQPVPTGVTGE 3040
Query: 310 VWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDA 366
+++ GA +A GY+ RF +P++ QP R+YRTGD G G ++Y GR D
Sbjct: 3041 IYIGGAGVARGYLNRPELTTERFVSDPYSEQPN-ARMYRTGDLGCWQPDGTIVYLGRNDF 3099
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVK+RG R++L E+E LA GV VV+ D G+ ++ +V +P A A +
Sbjct: 3100 QVKLRGFRIELGEIETQLAACLGVKDAVVVAREEDAGDKRLVAYVIPQPDASLDAASLRE 3159
Query: 427 KLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXX 485
+L + LT YM+P + +++ PL +GK+DR+ L + + + + E
Sbjct: 3160 QLSTHLTEYMLPSAFVILDAFPLTPSGKLDRKALPAPGRSASTSHEYEAP---------- 3209
Query: 486 XXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYY-VEISD 544
+LG G F+ELGGNSL+ + T LR+ + + I+D
Sbjct: 3210 -QGEIEPQLAAIWQTLLGLEQVGR---HDNFFELGGNSLSIMRLSTHLREEFHLEIPIAD 3265
Query: 545 FLGASTL 551
STL
Sbjct: 3266 IFHHSTL 3272
Score = 176 bits (429), Expect = 2e-42
Identities = 151/559 (27%), Positives = 248/559 (44%), Gaps = 34/559 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAGA YVP++P +P R+ +IL D+ P L++ + E +P +
Sbjct: 1644 VIGMLGILKAGAGYVPLDPEYPAERLAYILSDSAPKLLLTQQHLQAQLPVEK-LPVWQLD 1702
Query: 80 ELAQ--EATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ D P D L L +A ++YTSGSTG+PKGV + + + N + Q
Sbjct: 1703 DTGHLNSVAQQPTDNP-DPRQLG-LFPHHLAYIIYTSGSTGLPKGVMIEHHNVVNFTYSQ 1760
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ER 194
+T ++ + + +++F +V EI+ P L A LIL R P + E+
Sbjct: 1761 CQTSELKSTDRVLQF-ASVSFDTAVSEIF-PTLSVGATLILRPAHIRIPDATFSHFLQEQ 1818
Query: 195 LVLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ V PT + S ++ GE ++ ++ +
Sbjct: 1819 AISVIDLPTAFWHQWVQEMKAGRSGFSSHVRSVTVGGEK-AEHRHFVTWQSMPETRHCRW 1877
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
+ YG TE T L+G + ++ IGRPL N +Y+LD + P GE++
Sbjct: 1878 IDTYGPTETTVSATALTLDGPASY-VTESLSIGRPLINTHVYILDTQGQPVPIGVTGEIY 1936
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+ GA +A GY+ A RF +P QP R+YRTGD G G ++Y GR D QV
Sbjct: 1937 IGGAGVARGYLNRPELTAERFVSDPFREQPH-ARMYRTGDLGCWRPDGTIVYLGRNDFQV 1995
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG R++L E+E LA GV VV+ G+ ++ ++ K A + ++
Sbjct: 1996 KIRGFRIELGEIESQLAACTGVSDAVVVAREEGSGDKRLVAYLVPKSDVTLDAASLREQV 2055
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
+ L YM+P + +++ PL NGK+DR+ L D V +
Sbjct: 2056 STHLAEYMLPSAFVILDAFPLNPNGKLDRKAL--------PAPDHAATVSREYQAPQGEM 2107
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
T +LG G + F+ELGG+SL + I +LR +++S
Sbjct: 2108 EQQLAVIWQT---LLGLEQVGR---QDNFFELGGHSLLVVSLIEQLRQSSLNLDVSAVFS 2161
Query: 548 ASTLGEVLSKMSTDPNGGA 566
+ TL + +++ + GA
Sbjct: 2162 SPTLAAMAARLIVKTSDGA 2180
>UniRef50_Q0SEL9 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 3046
Score = 194 bits (474), Expect = 6e-48
Identities = 150/452 (33%), Positives = 220/452 (48%), Gaps = 25/452 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++AL+A KAGAAYVP++ P R +L DA P ++ ++ S VP +
Sbjct: 738 VVALVAVVKAGAAYVPIDADHPGERSALVLDDAHPVCILATRDTAHAL-PASDVPVLLLD 796
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +SAD DAE P+ +S+A V+YTSGSTG PKGV +S+ + +
Sbjct: 797 STDTDLGGNSADPLTDAER-PPVDPNSLAYVVYTSGSTGRPKGVAVSHRNVVSLFTSTRD 855
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + D++ ++ + F SV E+WG LLHG L+++ +TTR P + + R V
Sbjct: 856 LFRFGDTDVWTMFHSP-AFDFSVWEVWGALLHGGTLVVVDFDTTRSPAAFLALLRRDRVT 914
Query: 200 TLLRSILMYLAL--------GPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
L ++ + L G PLR + V GE L ++ G ED L
Sbjct: 915 VLSQTPTAFSQLIEATDTEDGAGPPPLRYV---VLGGEALDFGQLERWYSRHG-EDAPVL 970
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE VT+ L G T +GRP+ + +LD L P GE++
Sbjct: 971 VNMYGITETTVHVTHLPL-GRGLAAAAWTSKVGRPIPGFRVSVLDARLRPVPIGVAGELY 1029
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQV 368
VAG +A GY+G G A+RF + R+YRTGD + G++ Y GR D QV
Sbjct: 1030 VAGPQVARGYLGRAGLTASRFVADGSGA-----RMYRTGDVVRWRRDGSLDYLGRDDLQV 1084
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
+IRG RV+L EVE L + GV + VV + P +V + GA ++ +
Sbjct: 1085 EIRGFRVELGEVEWVLGRCDGVAQAVVTLHEDAVTGPAPAAYVVPEAGAIVDSEAVLEFA 1144
Query: 429 RSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
AL YM+P + + E +PL NGK+DR L
Sbjct: 1145 GGALPSYMVPASVTILERLPLTGNGKLDRAAL 1176
Score = 138 bits (335), Expect = 4e-31
Identities = 150/552 (27%), Positives = 228/552 (41%), Gaps = 44/552 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++ A K+GA++VP++P+ P GRI IL D V A+ GV + +
Sbjct: 1806 VVSVWAVAKSGASFVPVDPNLPPGRIADILADC--GAVAGLTVAEQRDRMPDGVEWLLLD 1863
Query: 80 ELAQEATSHSADEPM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
T P+ D + + PL A ++YTSGSTG PKGV + ++ + N Q
Sbjct: 1864 YPGP--TRRWESRPITDDDRVVPLRPGHPAYLMYTSGSTGAPKGVVIPHAGLQNFTIDQR 1921
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ +++ + A D+ + A L+++ L + +
Sbjct: 1922 ARYATTNASRVL--NLASPGFDATMLEYLMAFGAGARLVIAAPHVYGGAALTELLAAERI 1979
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + + P R LR L+ V GE EL + + G L YG T
Sbjct: 1980 THAFATPAVLATIDP--RGLRLLRALVVGGERCPPELLARW------ASGRTLLVGYGPT 2031
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T + D + + IG P+ +LDE L P GE++V G LA
Sbjct: 2032 E-----TTVMSNIGDPMTPGDPVRIGHPMRGVRELVLDEWLRPVPVGVVGELYVLGEGLA 2086
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHRV 375
GY G A F NP +P R+YRTGD K G + Y GR D QVK+RG RV
Sbjct: 2087 RGYHRRAGTTAASFVANPF-DRPG-SRMYRTGDLMRWTKEGRLEYLGRNDFQVKLRGQRV 2144
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+ EVE AL + PGV + VV+ + G+VT + GA + S L +
Sbjct: 2145 EPGEVEAALTRCPGVAQAVVVVRRTPAAEAVLAGYVTAEDGADLDTTEVLQFAGSVLAPF 2204
Query: 436 MMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P + V + +PL NGKVDR L D E A I
Sbjct: 2205 MVPASVTVLDRLPLGANGKVDRHAL----------PDPEFAPRI----FRAPGTPFESAV 2250
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLGE 553
VLG G + F+ GGNSL + + ++ G V + D T+
Sbjct: 2251 ADVFAEVLG---TGVVGADDDFFASGGNSLTATQVVARINSALGTDVGVRDVFETPTVRA 2307
Query: 554 VLSKMSTDPNGG 565
+ ++++ + GG
Sbjct: 2308 LAARIARESAGG 2319
>UniRef50_A7IZW1 Cluster: OciA; n=1; Planktothrix agardhii NIVA-CYA
116|Rep: OciA - Planktothrix agardhii NIVA-CYA 116
Length = 3477
Score = 194 bits (474), Expect = 6e-48
Identities = 158/563 (28%), Positives = 272/563 (48%), Gaps = 60/563 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA--- 76
I+ +L KAG AYVP++P +PQ R+ +L+D++ +++ S+ +
Sbjct: 2922 IVGILGILKAGGAYVPLDPEYPQERLNFMLEDSQVKVLVTQAKLVESIPQHQAQLICLDT 2981
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+E++AQ TS+ + + D++ ++YTSGSTG PKGV ++++ + RL+
Sbjct: 2982 DWEKIAQNITSNPE---------SGVKPDNLTYIIYTSGSTGKPKGVLVNHANVV-RLFA 3031
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---E 193
++ + +S+++ + F SV E+WG LL+G L+I+ TR P+ + E
Sbjct: 3032 ATDSWYHFNSQDVWTLFHSYAFDFSVWEMWGALLYGGRLVIVPYLVTRSPESFYELLCQE 3091
Query: 194 RLVLV---PTLLRSILMY--LALGPASRPLRR------------LKLWVCSGETLSKELA 236
++ ++ PT R ++ G S LR L+L + GE+L
Sbjct: 3092 KVTILNQTPTAFRQLIQAEESVKGDISPLLREVGKDSVTETDLSLRLVIFGGESLEINSL 3151
Query: 237 SEFFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLD 296
+F G++ +L N YG TE VTY L +D ++ ++ IGRPL + +YLLD
Sbjct: 3152 QPWFDRHGDQLP-QLVNMYGITETTVHVTYRPLSMAD-VNSTASV-IGRPLPDLQVYLLD 3208
Query: 297 EELSPTRDSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL- 353
+ L P PGE++V GA +A GY+ RF +P +LY+TGD
Sbjct: 3209 QYLQPVPVGVPGEMYVGGAGVAKGYLNRPELTTERFISSPFEHS---NKLYKTGDLARYW 3265
Query: 354 VKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT 413
G + Y GR D QVKIRG R++L E+E LA P + + VVL + G+ ++ ++
Sbjct: 3266 PNGELEYLGRIDNQVKIRGFRIELGEIEALLASHPQIWETVVLVWDDTAGDKRLVAYIVP 3325
Query: 414 KPGARTSAQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDA 472
+P I L++ L YM+P + +E++PL NGK+DR+ L
Sbjct: 3326 QPEITIIIDEIRQFLKAKLPDYMVPNAFVILEALPLTTNGKIDRRAL------------- 3372
Query: 473 EVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITK 532
++D S T+ + + + + + + F+ELGG+SL + + +
Sbjct: 3373 -PPPNLDISDKYVAPSTPIEEILATIWSEVLKVEK--VGINDNFFELGGHSLLATQLVAQ 3429
Query: 533 LRDR-GYYVEISDFLGASTLGEV 554
+RDR + + +TL E+
Sbjct: 3430 IRDRLKVELPLRQLFNTATLAEL 3452
Score = 181 bits (441), Expect = 6e-44
Identities = 140/458 (30%), Positives = 217/458 (47%), Gaps = 29/458 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +L KAGAAY+P++P +P R+ I++D+ L++ + +
Sbjct: 1866 IIGILGILKAGAAYLPLDPEYPPERLQFIIEDSGILLLLTQGFLKEKLLLTNLTNLNQIL 1925
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN-RLWWQF 138
L +++ S + ++T +DS+A V+YTSGSTG PKGV + +I N L W
Sbjct: 1926 YLDEQSFSLLLTDNPSSQT----KTDSLAHVIYTSGSTGKPKGVMIENRSIVNLALAWS- 1980
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
F ++ + + + L+F S+ EI L G +L + +ET Q LV+ E +
Sbjct: 1981 DVFQIQNNSRVLQFGS-LSFDLSIGEIATALAAGASLYLAQKETLLPSQILVDFLTENQI 2039
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L S L L PL L+ GE + +L +E+ K G N YG
Sbjct: 2040 SHAFLSPSALSVLP----QAPLPNLQSLTVGGEACTAKLITEWSK------GRNFFNAYG 2089
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T ++ + IGRP+ N IY+LD L P PGE+ + GA
Sbjct: 2090 PTETTVCATVARFTKDEE-----KVSIGRPVPNTQIYILDSYLQPVPIGVPGELHIGGAG 2144
Query: 317 LAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
LA Y+ +F NP + P+ RLY+TGD L G + Y GR D QVKIRG
Sbjct: 2145 LARSYLNRPELTQEKFIPNPFSNYPD-SRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGF 2203
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L Q P V V++ GN ++ ++ + A + + L+ L
Sbjct: 2204 RIELGEIETVLTQNPQVQSSVIIACEDTPGNKRLVAYIVPQKDATPTPNELRQFLKEKLP 2263
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNND 470
YM+P + +ES+PL NGK+DR+ L + ++ D
Sbjct: 2264 EYMIPSAFVILESLPLTPNGKIDRRALPEPEQSYERTD 2301
>UniRef50_Q88F79 Cluster: Non-ribosomal siderophore peptide
synthetase; n=1; Pseudomonas putida KT2440|Rep:
Non-ribosomal siderophore peptide synthetase -
Pseudomonas putida (strain KT2440)
Length = 3470
Score = 194 bits (473), Expect = 8e-48
Identities = 159/552 (28%), Positives = 257/552 (46%), Gaps = 42/552 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ L+A KAG AYVP++P +P R+ ++++D+ L++ + + + V +
Sbjct: 1622 VIGLMAVLKAGGAYVPLDPDYPSDRLAYMIEDSGIGLLLSQQALAERLPVPAAVRILCLD 1681
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ AQ ++ P LA ++A V+YTSGSTG PKG ++ A+ NRL W
Sbjct: 1682 QDAQWLAGYADTAPEVDVRLA-----NLAYVIYTSGSTGRPKGAGNTHEALLNRLQWMQG 1736
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
+ D+ + + KT +F SV E + PL+ G L + RDPQ+L +
Sbjct: 1737 AYGL-DASDTVLQKTPFSFDVSVWEFFWPLMTGARLAVALPGDHRDPQRLCQTIIDHQVS 1795
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L++ M A R +RR+ VCSGE L LA + + + Y N
Sbjct: 1796 TLHFVPSMLQAF-MASAEVEQCRSVRRV---VCSGEALPAVLAQQCRERLPHAGLY---N 1848
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ ++PIG+P+DN ++L+ +L P GE+++A
Sbjct: 1849 LYGPTEAAIDVTHWTCGDKQGF----SVPIGQPIDNLRTHILEPDLLPAARGVNGELYLA 1904
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G LA GY G A RF +P Q RLYRTGD G + YAGR D QVKI
Sbjct: 1905 GIGLARGYHGRPALTAERFVPDPFDEQG--GRLYRTGDLARYRPDGVIDYAGRIDHQVKI 1962
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG-KLR 429
RG R++L E+E LA+ V + VVL G +++G+V + G +LR
Sbjct: 1963 RGLRIELGEIEARLAEHAQVREAVVLAQDGPSGK-QLVGYVVPMAAEQAEPGSEAGQRLR 2021
Query: 430 SALTHYM---MPQVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L H++ +P + + LL N V G K+ N D A + +
Sbjct: 2022 EQLAHFLGQGLPDYMVPAHLMLLANLPVTANG--KLARNLLPAPDFNAARQVYVAPRTAL 2079
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
+ + ++ F+ LGG+S+ +I +++ R G + D
Sbjct: 2080 EQQLASIWETVLNL-------PQVGMQDNFFALGGDSIIAIQVVSQARQLGLDIAPRDLF 2132
Query: 547 GASTLGEVLSKM 558
T+ ++ +++
Sbjct: 2133 LLQTIEQLAARV 2144
Score = 165 bits (402), Expect = 3e-39
Identities = 134/455 (29%), Positives = 224/455 (49%), Gaps = 38/455 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA +KAG AYVP++P +P R+ ++++D+ L++ + + + + V +
Sbjct: 567 LVGLLAIFKAGGAYVPLDPDYPAERLAYMIEDSGLGLLLTEQAVLARLQVPATVASLCLD 626
Query: 80 -ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ A A++ + D P+D + +D A V+YTSGSTG PKGV + + A+ N L
Sbjct: 627 TDTACYASAAAEDLPLDVD------ADHPAYVIYTSGSTGRPKGVTVRHGALVNFL-TSM 679
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
P + + + T+L+F + E++ PLLHG ++++L+ + +DP L+ + V
Sbjct: 680 AVQPGIAASDRVLALTSLSFDIAGLELYLPLLHGASVVLLADQQNKDPFALLRVIEQQAV 739
Query: 199 PTLLRSILMY-LALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ + + + L A R K + GE LS ELA G+ + N YG
Sbjct: 740 SVIQATPSTWRMLLDNAPPQALRGKRVISGGEALSSELAQRLIDQAGH-----VWNLYGP 794
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + G +++ + +G+P+ N ++LD + GE+++ G L
Sbjct: 795 TETT------IWSGIEKVTDSRQVWLGKPIGNTTFHVLDAQFDAVPVGVSGELFIGGDGL 848
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHR 374
A GY+ G A RF NPH RLYRTGD VL Y GR D Q+KIRG R
Sbjct: 849 ARGYLKRPGLTAERFIPNPHG----HGRLYRTGDLVRYRDDGVLEYMGRIDHQLKIRGFR 904
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ-HIEGKLRSAL- 432
++L E+E +L V + V+ G ++ G++ + A ++ LR AL
Sbjct: 905 IELGEIEASLQGFGAVREVAVIDVDGPLGK-QLAGYIVPYDASLLQADAEVQETLRLALK 963
Query: 433 TH-------YMMP-QVIEVESIPLLVNGKVDRQGL 459
H YM+P ++ + +PL NGK+DR+ L
Sbjct: 964 AHALKSMPDYMVPTHLVFIPRMPLTPNGKLDRKAL 998
Score = 153 bits (371), Expect = 2e-35
Identities = 154/556 (27%), Positives = 261/556 (46%), Gaps = 66/556 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA KAGAAYVP++ ++P R++++++D+ +L++ +A + K + V + +
Sbjct: 2682 IVALLAVLKAGAAYVPIDTAYPAERLSYLMEDSGVALLVSQTAALAGLPKLANVHALNLD 2741
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAI---CNRLWW 136
+ T P L +++A V+YTSGSTG PKGV +S+ A+ C +
Sbjct: 2742 SF--DPTQWPGHAPQ-----VTLQGENLAYVIYTSGSTGKPKGVVVSHDALAMHCQAIGE 2794
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIW-GPLLHGRALLILSRETTRDPQKLVNIER- 194
++ P +D E + + + F D E W L HG ++L+ E Q + R
Sbjct: 2795 RYEMTP-ADCELLFM---SFAF-DGAHERWLTALTHGGSVLLRGDELWTPEQTCQALHRH 2849
Query: 195 ----LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
P L+ ++ + P+R ++ G+ + + + Y + Y
Sbjct: 2850 GVSVAAFPPVYLQQLIEQVREHGNPPPMR---IYCFGGDAVPQASYEQAHAYL--QPQY- 2903
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPT-IPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
+ N YG TE + VT + + + Q PIG + + Y++D +L+P GE
Sbjct: 2904 IINGYGPTETV--VTPTIWKAAPQQPCGAVYAPIGTLVGQRSAYVMDVDLNPLPPGVAGE 2961
Query: 310 VWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDA 366
+++ G +A GY+ G A RF +P P RLYRTGD G Y GR D
Sbjct: 2962 LYLGGTGVARGYLNRPGLTAERFVADP--GNPG-GRLYRTGDLVRQREDGTFDYLGRLDN 3018
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG-ARTSAQHIE 425
QVK+RG R++L E+E LA + V + V+ G ++ G+VT G A+ A+ +
Sbjct: 3019 QVKVRGFRIELGEIEARLADMDPVRQAAVVVRDGPSGK-QLFGYVTLAEGHAQGIAEQLR 3077
Query: 426 GKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMY---ENTNNNDDAEVAVDIDCS 481
+L+ L YM+P Q++ +E +PL NGK+DR L M E+ ++ E+A+
Sbjct: 3078 ERLKQELPEYMVPAQLMVLERMPLSPNGKLDRNALPAMQALREHVAPRNELELAI----- 3132
Query: 482 XXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITK---LRDRGY 538
VG + F+ELGG+S+ S+ + K L+ G+
Sbjct: 3133 ----ARIWQDVLKVEQVG------------ITDNFFELGGDSILSMQVVAKARGLKKIGF 3176
Query: 539 YVEISDFLGASTLGEV 554
+ + D + ST+ E+
Sbjct: 3177 TLRLRDLIQKSTIAEL 3192
>UniRef50_Q5JCL8 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Pseudomonas fluorescens|Rep: Putative non-ribosomal
peptide synthetase - Pseudomonas fluorescens
Length = 1432
Score = 194 bits (473), Expect = 8e-48
Identities = 142/444 (31%), Positives = 224/444 (50%), Gaps = 36/444 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I ALL +AG A++P++P P RI +++++ LVI D ++S +
Sbjct: 509 IAALLGVVRAGHAFLPIDPRLPTDRIQFLIENSGCELVITSD-------QQSVEGWPQVA 561
Query: 80 ELAQEATSHSADEPMDAETLAP--LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ EA +P D +AP L+ A ++YTSGSTG+PKGV + + + N + W+
Sbjct: 562 RIRMEAL-----DP-DIRWVAPTGLSHSDAAYLIYTSGSTGVPKGVVVEHRQVVNNILWR 615
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERL 195
RT+P + + + + + +F SV ++ PLL G +++ T D L++ I
Sbjct: 616 QRTWPLTAQDNV-LHNHSFSFDPSVWALFWPLLTGGTIVLADVRTMEDSTALLDLMIRHD 674
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
V V + S+L L P + R +KL + GE L+ ELA + K + + +AN Y
Sbjct: 675 VSVLGGVPSLLGTLIDHPFANDCRAVKLVLSGGEVLNPELAHKIQKVWQAD----VANLY 730
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE D Y+ ++ + IPIG P+DN Y++D L+P PGE+ +AG
Sbjct: 731 GPTEATIDALYFSIDKNAA----GAIPIGYPIDNTDAYIVDLNLNPVPPGVPGEIMLAGQ 786
Query: 316 NLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIRG 372
NLA GY+G A RF NP R+Y TGD G GA+ Y GR D QVKIRG
Sbjct: 787 NLARGYLGKPAQTAQRFLPNPFGN----GRVYATGDLGRRWSSGAISYLGRRDQQVKIRG 842
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
HR++L EV L Q + + +V ++ + +PG ++ I+ +L L
Sbjct: 843 HRIELNEVAHLLCQALELKEAIVFAQHAGTEQARLVAAIEQQPGLH--SEGIKQELLRHL 900
Query: 433 THYMMP-QVIEVESIPLLVNGKVD 455
Y++P Q++ ++ +P GKVD
Sbjct: 901 PAYLIPSQLLLLDELPRTATGKVD 924
>UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2;
Streptomyces|Rep: Pristinamycin I synthase 3 and 4 -
Streptomyces pristinaespiralis
Length = 4848
Score = 194 bits (473), Expect = 8e-48
Identities = 174/551 (31%), Positives = 256/551 (46%), Gaps = 63/551 (11%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ALLA K GAAY+P++ S+P RI +++DA P V+ +
Sbjct: 3014 VALLAVLKTGAAYLPVDISYPAERIAFMIEDARPVTVL--------------------DR 3053
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
L + ++ + DA+ APL + A V++TSGSTG PK V + ++ + N L W R
Sbjct: 3054 LPDDLGAYRDTDLTDADRTAPLRPEHPAYVIHTSGSTGTPKAVVMPHAGLANLLTWHARR 3113
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVPT 200
FP + TA+ F SV EI PL+ G+ L + S E + L +
Sbjct: 3114 FPGGTGVRTAQF-TAIGFDFSVQEILSPLVMGKTLAVPSEEVRHSAELLAGWLETQQINE 3172
Query: 201 LLRSILMYLALGPAS----RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L L+ AL A+ R L L + GE L+ + G +L N YG
Sbjct: 3173 LFAPNLVIEALAEAAAEAGRTLPDLTDILQGGEALAP--TERVRAFTAAVPGRRLHNVYG 3230
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E VT + L +D P+ PIGRP+D+ +Y+LD L P GE+++AGA
Sbjct: 3231 PAETHA-VTTHTL-AADPAHWPPSAPIGRPVDHDRVYVLDSALRPVPPGVTGELYLAGAG 3288
Query: 317 LAAGYV--GGGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
+A GY+ A RF +P+A +P R+YRTGD G +G + +AGR D QVKIRG
Sbjct: 3289 VARGYLHRPRTTAERFVADPYAPRPG-ARMYRTGDLGRWNTRGELEFAGRADHQVKIRGF 3347
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
RV+ EVE AL P + + VL +G DR ++ +V T A + L + L
Sbjct: 3348 RVEPGEVEAALTAHPRITQAAVLAHG-DR----LVAYVVTT--ADRDLTGVREHLAARLP 3400
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
+M+P + +E++PL VNGK+DR L V +I C
Sbjct: 3401 DFMVPTAYVRLEALPLTVNGKLDRAALPAPDAPAAGRAPRTVREEILCG----------- 3449
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGAST- 550
VLG G + F++LGG+SL + I+++R G + + D A T
Sbjct: 3450 ----LFAEVLGTERAG---IDDNFFDLGGHSLLATRLISRIRTALGAEITLRDLFEAPTV 3502
Query: 551 --LGEVLSKMS 559
LGE L + S
Sbjct: 3503 AGLGERLDQAS 3513
Score = 183 bits (446), Expect = 1e-44
Identities = 140/449 (31%), Positives = 214/449 (47%), Gaps = 37/449 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ALLA K GAAY+P++ ++P RI ++ DA P++V+ + E+
Sbjct: 530 VALLAVLKTGAAYLPVDTAYPAERIAFMMDDARPAVVL------------------TGED 571
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
Q+ + + + DA+ APL A V+YTSGSTG PK V + +A+ N L W R
Sbjct: 572 TGQDLSGYDDTDLTDADRTAPLLPAHPAYVIYTSGSTGTPKAVVMPGAALVNLLAWHRRE 631
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIER 194
P + + T + F + EI LHG+ L + S+E R ++L ++
Sbjct: 632 IPGEAGAPVAQF-TTIGFDVAAQEILATWLHGKTLAVPSQEVRRSAEQLAAWLDEQHVSE 690
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
L P L+ L A A R L L+ +GE L+ L ++ G +L N
Sbjct: 691 L-YAPNLVIEALAE-AAAEAGRTLPALRHIAQAGEALT--LTRTVREFAAAVPGRQLHNH 746
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG E V D P+GRP+ +Y+LD L P GE+++AG
Sbjct: 747 YGPAET--HVMTGTALPEDPAAWSEHAPLGRPVSGARVYVLDSALRPVAPGVTGELYLAG 804
Query: 315 ANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
A ++ GY+ A RF +P+A P R+YRTGD G +G + +AGR D QVKIR
Sbjct: 805 AGVSRGYLNRPVLTAERFVADPYAPSPG-ARMYRTGDLGRWNTRGELEFAGRADHQVKIR 863
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++ E+E AL +P V + V+ DR + L G A + +L
Sbjct: 864 GFRIEPGEIEAALTDLPAVARAAVVVRE-DRPGDKRLVAYAVPAGEGLDAAAVRSRLART 922
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +M+P ++ ++++PL NGK+DR L
Sbjct: 923 LPDFMVPAAIVALDALPLTPNGKLDRAAL 951
Score = 172 bits (419), Expect = 3e-41
Identities = 133/451 (29%), Positives = 210/451 (46%), Gaps = 30/451 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LA KAG YVP+ +P R+ H+L D E +L++ D+ + P + +
Sbjct: 4061 VVTTLAILKAGGVYVPLHTGYPVDRMRHVLADTEAALLL-TDTHHAATAARLDTPALTVD 4119
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYS---AICNRLWW 136
E + T+ D T+ P D +A +++TSGSTG PKG+ +++ A+ W
Sbjct: 4120 E---DTTAGEQDTTAPDVTVRP---DQLAYIMFTSGSTGTPKGIGITHRDAIALAADRCW 4173
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
D+ + + F S E++ PLL G +++ R +
Sbjct: 4174 DL------DTGSRVLMHSPYAFDISTFELFAPLLAGGRIVVAPRGDIDAAVLQRTLAAHG 4227
Query: 197 LVPTLLRSILMYLALGPASRPLRRLK-LWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ LL + L+ + A +K +W G+ +S + G + Y
Sbjct: 4228 VTSLLLTAGLLGVIADEAPEVFTGVKDVWT-GGDVVSPTAVRRVLEAC---PGTVVKTLY 4283
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T+ L +D + P +PIGRPLDN Y+LDE L P GE+++AGA
Sbjct: 4284 GPTETTLGCTW--LPFTDPRRIPPAVPIGRPLDNTRAYVLDERLRPVPPGVTGELYIAGA 4341
Query: 316 NLAAGY--VGGGGANRFCDNPHA--TQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
LA GY A RF +PHA R+YRTGD G + + GR D QVKI
Sbjct: 4342 GLARGYWDQSARTAERFTADPHAHLFGDTGGRMYRTGDLARRDADGVLHFCGRADQQVKI 4401
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLR 429
RG R++ E+E ALA P V + V+ G+ ++ ++ T P A T+A+ + L
Sbjct: 4402 RGFRIEPGEIETALAAHPDVTRAAVVARPGRAGDKVLVAYLVTAPDAGDTTAEQLRAGLE 4461
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ L YM+P + + ++P+ NGK+DR L
Sbjct: 4462 TQLPDYMVPAAFVALPALPVTPNGKLDRDAL 4492
Score = 145 bits (352), Expect = 3e-33
Identities = 124/400 (31%), Positives = 189/400 (47%), Gaps = 41/400 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+LA WK+GAAY+P++P +P RI H+ DA P+LV+ D D +
Sbjct: 1581 VTAVLAVWKSGAAYLPVDPDYPPERIAHMRADARPALVV-DAIPDDTT------------ 1627
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA A S D A+ APL A V+YTSGSTG PKGV +++ ++ + Q
Sbjct: 1628 -LAAYADSRLTD----ADRSAPLLPAHPAYVIYTSGSTGAPKGVVVAHRSLAATVPAQAA 1682
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
F + + +++F +V E+ L G L++ + L + +R +
Sbjct: 1683 AFGLGTHSRVLNF-ASISFDAAVWELTSALFTGAGLVLADADDLLPGPSLARLVHDRHIT 1741
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ L S L L G A P L + +G+ + + A+ F G ++ N YG
Sbjct: 1742 LIALPPSALPALPDG-ALPPGTDL---IVAGDATAPDQAARF------APGRRMVNAYGL 1791
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T D PIGRP+ + +Y+LDE L P GE++V+GA +
Sbjct: 1792 TETTVCATMSEPATGDGAP-----PIGRPVAHARVYVLDERLRPVPPGVTGEMYVSGAGV 1846
Query: 318 AAGYVGGGG--ANRFCDNPHAT--QPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
A GY+ A RF +P+A R+YRTGD L G + +AGR D QVKIRG
Sbjct: 1847 ARGYLHRPALTAQRFVPDPYALLFGETGTRMYRTGDLARLDADGRLHFAGRADQQVKIRG 1906
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT 412
R++ E+E L P V V+ G+ +++ ++T
Sbjct: 1907 FRIEPGEIETVLTAHPAVAAGAVIAREDTPGDKQLVAYLT 1946
>UniRef50_Q0LP45 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1528
Score = 194 bits (472), Expect = 1e-47
Identities = 150/477 (31%), Positives = 232/477 (48%), Gaps = 42/477 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIY-DDSADPSMFKESGVPFASF 78
I++LLA KAGAAY+P++P++P R+ +++ D+ SL++ A P++ V A
Sbjct: 533 IISLLAILKAGAAYLPLDPAYPAERLHYLVADSAASLIVQASHQALPTL-----VSTAET 587
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
++ EA + A P A + +A V+YTSGSTG PKGV + + + N L W
Sbjct: 588 LDVVAEAET-LASLPTTA-PMVDFDPQQLAYVIYTSGSTGKPKGVLIQHQGVVNYLHWAI 645
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRD--PQKLVNIERLV 196
+P+ + ++L F ++ +WGPL G+ + +L + + Q+L + + V
Sbjct: 646 HYYPFEQGAGAPL-ASSLAFDATITALWGPLCTGKTIDLLPEQDELEVLAQRLSSEDYSV 704
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L T + + P + K +V GE L ++ + F++ N +L N YG
Sbjct: 705 LKITPAHMEALSQLVAPDQ--IGSSKAFVIGGEALLQQHVA-FWQ--TNAPNLRLINEYG 759
Query: 257 STE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE V+G V Y + + +PIGRP+ N +Y+LD P PGE+++AG
Sbjct: 760 PTETVVGCVIYQAQAAPSE---WAAVPIGRPIANTQLYVLDPAGLPVPIGVPGELYIAGL 816
Query: 316 NLAAGYVGGG--GANRF---------------CDNPHATQPEFQRLYRTGDF-GTLVKGA 357
+ GY G A RF C P QP F+RLYR+GD L G
Sbjct: 817 GVGRGYHGRPELTAERFVRLEQLAGVQAELARCQQP---QPAFERLYRSGDLVRYLPDGN 873
Query: 358 VLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA 417
+ Y GR D QVK+ G R++L E+E LA P V V + G+ ++ +V +P A
Sbjct: 874 LEYLGRIDQQVKLHGFRIELGEIEATLASHPTVHAAVAMIREDRPGHKRLVAYVVAEPTA 933
Query: 418 RTSAQHIEGKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAE 473
+ + L HYM+P VI ++S+PL NGKVDRQ L N D A+
Sbjct: 934 NQDTSIVLTHVAQQLPHYMLPSVVIWLDSLPLTPNGKVDRQALPAPEINQTALDSAQ 990
>UniRef50_Q8YTR4 Cluster: All2649 protein; n=3; Nostocaceae|Rep:
All2649 protein - Anabaena sp. (strain PCC 7120)
Length = 1583
Score = 193 bits (471), Expect = 1e-47
Identities = 137/450 (30%), Positives = 224/450 (49%), Gaps = 27/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA KAG AY+P++ P R+ ++L DA+P +++ ++ + G E
Sbjct: 577 IIALLAVLKAGGAYIPLDNKLPPERLAYMLGDAQPRIILTMAASVTGLPDYQGTVICLDE 636
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A + + + P +T +++A ++YTSGSTG PKGV L++ + N L W +
Sbjct: 637 DWQSIAQNPTENLPNI------VTGENLAYIIYTSGSTGKPKGVMLTHRGLANYLQWAIQ 690
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLIL--SRETTRDPQKLVNIERLVL 197
T+P + V ++A++F ++ ++ PLL G+A+++L + E L + L
Sbjct: 691 TYPVDLGVGVPV-QSAISFDATITSLYTPLLVGKAVILLPEAEEIEALKNALSSARNFSL 749
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + + L P P + ++ GE L+++ + YF KL N YG
Sbjct: 750 VKLTPAHLSILSQLLPQKVPAGYPQAFIIGGEALTEQHLEFWRSYFPQT---KLINEYGP 806
Query: 258 TE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE V+G Y +G +PIGRP+ N +Y+LD L P PGE+++ GA
Sbjct: 807 TETVVGCCIYDASQGKSSKG---NVPIGRPIANTRLYILDRYLQPVPIGVPGELYIGGAG 863
Query: 317 LAAGYVGGG--GANRFCDNP---HATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
+A GY+ A RF ++ Q LY+ GD L G + Y GR D QVKI
Sbjct: 864 VARGYLNRPELTAERFISQQSTVNSQQSTVNTLYKPGDRARYLSDGTIEYLGRLDDQVKI 923
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG RV+L E+E L P V + VV+ + + +++ ++ Q++ KL +
Sbjct: 924 RGFRVELGEIEAILKAHPSVQEAVVILQKVHPQSSQLVAYLVGNQQTVDFRQYLATKLPA 983
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + +E +PL NGKVD+Q L
Sbjct: 984 ----YMLPSAFVWLEQLPLTTNGKVDKQQL 1009
>UniRef50_Q0LN53 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1145
Score = 193 bits (471), Expect = 1e-47
Identities = 158/529 (29%), Positives = 256/529 (48%), Gaps = 50/529 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +L KAGAAY+P++P P RI +L DA+ +L++ +S S+ ++ +
Sbjct: 587 IIGILGILKAGAAYLPLDPQLPTSRIEWMLADAQVNLIVTQNSLLHSVNSQA----TTIL 642
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L Q T+ P T+ P D +A ++YTSGSTG PKG LS++ +
Sbjct: 643 NLDQLPTTKLTQLP----TIHP---DQLAYIIYTSGSTGQPKGTLLSHANVLRLFEATVA 695
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIER 194
T S ++ VW + F SV EIWG LL+G L+++ TTR P+ +L+ E
Sbjct: 696 TIKPSAND---VWSLFHSYAFDFSVWEIWGALLYGGRLVVVPSTTTRSPEAFSQLLADES 752
Query: 195 LVLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ ++ P+ R +L L PA L+L + GE L + +++ + +L
Sbjct: 753 ITVLNQTPSAFRQLLPQLT--PAVAANLALRLIIFGGEALDLASLAAWYQAYP-APAPQL 809
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE VT LE +D ++ ++ IG P+ + +YLLD+ GE++
Sbjct: 810 LNMYGITETTVHVTERWLELNDLIEAKASL-IGLPIADLTMYLLDQYGQLVPQGAVGEIY 868
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQV 368
V GA LA GY+ A RF +P ++ RLYR+GD + + G + Y GR+D QV
Sbjct: 869 VGGAGLARGYLKQAALTAQRFVPDPWSSTGA--RLYRSGDLARINQFGELEYLGRSDQQV 926
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L E+E+A+ + GV C LD+ ++ V +P S + + L
Sbjct: 927 KLRGFRIELGELEQAICRQAGVADCWAFVQKLDQHERLVVWVVPNQPA--LSVEQLRQAL 984
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
L HY+ P + + E +PL NGK D A + +D +
Sbjct: 985 ALELPHYLQPNLWLLCEHLPLTNNGK---------------RDYAHLLAQLDVTLEQASS 1029
Query: 488 XXXXXXXXXTVGAV-LGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
+ A+ L + S+ F+E+GGNSLN++ +T++R+
Sbjct: 1030 IAPNNPIQALIAAIWLEILQQPIASIDQNFFEVGGNSLNAVLVLTRIRE 1078
>UniRef50_A3INW8 Cluster: Peptide synthetase; n=3;
Chroococcales|Rep: Peptide synthetase - Cyanothece sp.
CCY 0110
Length = 1876
Score = 193 bits (471), Expect = 1e-47
Identities = 141/445 (31%), Positives = 226/445 (50%), Gaps = 31/445 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG Y+P++P++P RI +IL+ ++ ++++ ++KE+ +
Sbjct: 557 LIGLLAILKAGGTYIPIDPTYPSERINYILEHSQVNVIL----TQSWVWKENREKYTIIA 612
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ T H P LT +A ++YTSGSTG PKGV +S+ I N LW +
Sbjct: 613 --IDKITLH----PTPYTPHPHLTPQDLAYIIYTSGSTGKPKGVEISHQGIVNFLWSMAQ 666
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVLV 198
P +S++I + T L+F + E++ PL+ G ++I+SR+T D L I++
Sbjct: 667 Q-PGINSDDILLSVTTLSFDIAGLELFLPLITGAKVVIVSRQTVIDGVALSQKIDQSNAS 725
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + + + LK+ +C GE LSK L E +L N YG T
Sbjct: 726 MMQATPATWQMLIDAGWKGKKDLKI-LCGGEALSKTLVKELLT-----KSQELWNMYGPT 779
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + ++E +++ I IGRP++N IY+LD L P PGE+++ G LA
Sbjct: 780 ET---TVWSMIE---KIETEDNITIGRPINNTQIYILDNHLQPVPIGIPGELYIGGDGLA 833
Query: 319 AGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GYV RF ++P P +++Y+TGD L G V Y GR+D QVKIRG R+
Sbjct: 834 RGYVNRRDLTEERFINSPF--NPG-KKIYKTGDIAKYLPNGKVEYIGRSDYQVKIRGFRI 890
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E L Q GV VV+ G ++ + ++ + + +++ L+ L Y
Sbjct: 891 ELGEIESQLNQHLGVKNAVVVAKKEASGINPLVAYYVSQKESNVTDENLRDFLKKKLPDY 950
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGL 459
MMP V I + PL NGK+DR+ L
Sbjct: 951 MMPLVFISLAEFPLTPNGKIDRKAL 975
>UniRef50_A0ZF79 Cluster: Non-ribosomal peptide synthase; n=6;
Cyanobacteria|Rep: Non-ribosomal peptide synthase -
Nodularia spumigena CCY 9414
Length = 2195
Score = 193 bits (471), Expect = 1e-47
Identities = 140/449 (31%), Positives = 229/449 (51%), Gaps = 24/449 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAGAAY+P++P++P+ RI+ +L D++ +++ S F ESGV +
Sbjct: 105 IVGLLGILKAGAAYLPLDPTYPKERISFMLADSQVQVLLTQQKFLES-FTESGVKTVCLD 163
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + T + + P + +T++++A V+YTSGSTG PKGV + + A+ NRL
Sbjct: 164 QDWELITQQNPENPT-----SNVTAENLAYVIYTSGSTGTPKGVPVPHRAV-NRLVCNTN 217
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
++ ++ +F + EIWG LLHG L+ + + P E+ +
Sbjct: 218 YVQFTTTDRTAQASNT-SFDAATFEIWGSLLHGATLVGVPQNVLLSPVDFAAYIQEQKIN 276
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ L ++ LA + + L+ + GE + + + + +L + YG
Sbjct: 277 ILFLTTALFNQLA-NIVPQAFKDLRYLLFGGEAVDPKTVRAVLTHGAPQ---QLLHVYGP 332
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE +Y +E + T+PIGRP+ N IY+L+E+L P PGE+++ G L
Sbjct: 333 TESTTYSCFYPVENVPEGAT--TLPIGRPISNTQIYILNEQLQPVPVGTPGEIYIGGDGL 390
Query: 318 AAGYVGGG--GANRFCDNP-HATQPEFQ--RLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
A GY+ A RF +P H + + Q +LY+TGD L G + + GR D QVKIR
Sbjct: 391 ARGYLNRPELTAERFISHPFHNPKSKIQNPKLYKTGDLARYLPDGNIEFVGRVDNQVKIR 450
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L EVE AL+Q P + + VV+ G+ ++ +V A T A + L
Sbjct: 451 GFRIELGEVEAALSQHPDIQQAVVIVREDIPGDKRLVAYVVPDQKAVT-ATTFKSFLEDK 509
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + ++ +PL NGKVDR+ L
Sbjct: 510 LPAYMVPTAWMLLDFLPLTPNGKVDRRSL 538
Score = 157 bits (381), Expect = 1e-36
Identities = 142/546 (26%), Positives = 244/546 (44%), Gaps = 44/546 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I LL KAG AYVP++P++PQ RI ++ D + +++ + + SG
Sbjct: 1186 IAGLLGILKAGGAYVPIDPAYPQERIAEMIADTQLGILLTQNRFQEKLVGYSGQTICLDT 1245
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A+ AT A+ D + + +A ++YTSGSTG PKGV + + ++ N +
Sbjct: 1246 DWAKIATQSPANPVSDVQL------NHLAYIIYTSGSTGKPKGVMIEHRSLLNFVTTAID 1299
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRE---TTRDPQKLVNIERLV 196
+ + +++ + ++ F S+ EI+ L G L++ + E ++ D + +L
Sbjct: 1300 EYGINAQDQVLQF-ASVCFDTSIEEIFPCLAVGATLVLRTEEMLNSSDDFWRCCQKWQLT 1358
Query: 197 LV--PTLLRSILMYLALGPASRPL-RRLKLWVCSGETLSKELASEFFKYFGN-EDGYKLA 252
++ PT L+ L P + P+ L+ + GE + E + + +L
Sbjct: 1359 VLDLPTAYWHQLV-TELQPQNSPIPASLRTVIIGGEEVQLEKVQHWHNCTAHLSPAPQLF 1417
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE T L + ++ IG+P+ N +Y+LD+ PGE+ +
Sbjct: 1418 NTYGPTEATVVTTLERLTPENT-----SVSIGKPISNAQVYILDQYQQTVPIGVPGELHI 1472
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVK 369
GA LA GY A +F +N E RLY+TGD + G + Y GR D QVK
Sbjct: 1473 GGAGLARGYWQRPELTAEKFIENT-----EGNRLYKTGDLVKFRRDGNLEYLGRVDNQVK 1527
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG R++L E+E L Q P V + VV+ + G ++ + + G + + + L+
Sbjct: 1528 IRGFRIELGEIETVLRQHPQVSQAVVIAHQEITGQKRLVAYFLPQ-GPQPTIDELRQFLK 1586
Query: 430 SALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
L +YM+P V +SIP+ N KVD + L + + +D+ + A
Sbjct: 1587 QKLPNYMIPAAFMVLDSIPMTPNQKVDYRAL--PTPDFSRSDEDKFAAPRTLIEEKLVAI 1644
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
VG + ++ELGG+S+ SI ++K G +
Sbjct: 1645 WSEVLRIENVG------------IHDNYFELGGDSILSIQLVSKANQAGIQIAAKQLFRY 1692
Query: 549 STLGEV 554
T+ E+
Sbjct: 1693 QTIAEL 1698
>UniRef50_Q9AMR5 Cluster: ID930; n=1; Bradyrhizobium japonicum|Rep:
ID930 - Bradyrhizobium japonicum
Length = 3310
Score = 193 bits (470), Expect = 2e-47
Identities = 165/549 (30%), Positives = 256/549 (46%), Gaps = 37/549 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG +Y+P++P++P R+ +L DA P L++ D A + F S
Sbjct: 1418 VVGLLAILKAGGSYMPLDPAYPSARLHQVLDDAAPPLLLAD-VAGRAAFGADVPAKVSVV 1476
Query: 80 ELAQEATSHSADEPMDAETLA-PLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
EL A + ++ D + A LTS ++A V+YTSGSTG PKG + + AI NRL W
Sbjct: 1477 ELDAAAPAWASLPEADPDRRALSLTSRNLAYVIYTSGSTGRPKGAQNEHRAIVNRLIWMQ 1536
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERL 195
+ + ++ + KT +F S E + LL G L++ RDP LV++ +R+
Sbjct: 1537 DAYGLKPT-DVVLQKTPFSFDVSAWEFFWTLLEGATLVLAPPGAHRDPDTLVDLIVSQRI 1595
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
V + ++ +L R L+ +CSGE L A+ ++ L N Y
Sbjct: 1596 TTVHFVPSMLVSFLDAKSVDR-CTSLRQVLCSGEALP---AASVYRVRRVLPWTALHNLY 1651
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE DVT + + D +PIGRP+ N +YLLD +P GE+ + GA
Sbjct: 1652 GPTEAAIDVTSWSCPA--EFD-EAIVPIGRPIANTRVYLLDGHGAPVPFGAVGELCIGGA 1708
Query: 316 NLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
+A GY+ A RF +P E RLYRTGD L G + + GR D QVKIRG
Sbjct: 1709 GVARGYLNRPELTAERFIPSPFV---EGDRLYRTGDLARYLPDGNLEFLGRNDDQVKIRG 1765
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS--AQHIEGKLRS 430
R++ E+ L + V + VV+ G ++ +V GA S A + + +
Sbjct: 1766 FRIEPGEIAARLCEHASVREAVVVAREDGGGEQRLVAYVVA-AGAEESDLAGGLRAHVSA 1824
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P + + ++PL +NGK+DR+ L D+A A
Sbjct: 1825 GLPDYMVPSAFVRLAALPLTLNGKLDRKAL------PAPGDEA-YARRTYAPPQGEMETV 1877
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
+G L R R F+ELGG+SL ++ + LR R +E+
Sbjct: 1878 LAQIWAELLG--LERVGR-----HDNFFELGGHSLLAVQMMEHLRRRSLRIEVRTLFVKP 1930
Query: 550 TLGEVLSKM 558
L ++ +++
Sbjct: 1931 VLADLAARL 1939
Score = 175 bits (426), Expect = 4e-42
Identities = 146/458 (31%), Positives = 228/458 (49%), Gaps = 34/458 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AY+P++P++P R+ I+ DAEP L++ D + ++ E+ V +
Sbjct: 347 VVGLLAILKAGGAYLPLDPAYPSARLRQIVGDAEPKLLLCDVAGRTALGAEA-VADVTVV 405
Query: 80 ELAQEATSHSADEPMDAETLA-PLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+L + P + + A L+S +A V+YTSGSTGIPKGV +S+ A+ N L
Sbjct: 406 DLETATPTWGERPPSNPDPGALGLSSRHLAYVIYTSGSTGIPKGVEMSHGALVNSL---- 461
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVL 197
S+ + L F S E++ G L+++ ET R L+ IER +
Sbjct: 462 --AGIGTSKLRTLQFATLNFDVSCQELFICWKDGGVLVLVREETRRHFSDLLEFIEREAI 519
Query: 198 VPTLLRSILM--YLALGPASR-PLRRLKLWVCSGETL-SKELASEFFKYFGNEDGYKLAN 253
L + + + + A R L L+ +GE L + L FF+ N +L N
Sbjct: 520 ERLFLPFVALNHFAEVWSAQRVQLPSLRELYTAGERLQATPLLRTFFEAHPNA---RLIN 576
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIP-IGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YGSTE+ +++ +D +P +P +GRP+ N +YLLD +P GE+++
Sbjct: 577 QYGSTEISVISEHHL--AADP-SCWPQMPHVGRPIVNTRVYLLDGHGAPVPFGAVGELYI 633
Query: 313 AGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
GA +A GY+ A RF +P E RLYRTGD L G + + GR D QVK
Sbjct: 634 GGAGVARGYLNRPELTAERFIASPFV---EGDRLYRTGDLARYLPDGNLEFLGRNDDQVK 690
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS-------AQ 422
IRG+R++ E+ L + V + VVL D G+ ++ +V P A + A
Sbjct: 691 IRGYRIEPGEIVARLCEHAWVREAVVLARENDAGDKHLIAYVVCAPEAGSDEGGGGGLAG 750
Query: 423 HIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ L + L YM+P + + ++PL VNGK+DR L
Sbjct: 751 ALRAHLSARLPDYMVPSAFVRLAALPLTVNGKLDRNAL 788
Score = 164 bits (398), Expect = 9e-39
Identities = 137/454 (30%), Positives = 207/454 (45%), Gaps = 33/454 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKE--SGVPFAS 77
++ +LA KAG AY+P++P++P R+ ++ DA P L++ D ++ E + V
Sbjct: 2507 MVGILAILKAGGAYLPLDPAYPSERLRQVVNDAAPRLLLCDVVGRAALGPEVLTEVTVID 2566
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E A P D TL LTS +A V+YTSGSTG PKGV + + + N L Q
Sbjct: 2567 LETATPAWAERPASNP-DRHTLG-LTSGHLAYVIYTSGSTGTPKGVMVQHRGLVNLLSAQ 2624
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
F S + + V ++ F S E+ G AL + + E + KL + R
Sbjct: 2625 VGLFGASSNSRV-VQFASIAFDASAWELLMAFGSGAALHLPAEEIRQARNKLSDYLR--- 2680
Query: 198 VPTLLRSILMYLALGPASRPLR-RLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ + L L + P R ++ + +GE EL + N YG
Sbjct: 2681 SEAITHATLPPALLQTSKDPERLAAQVLILAGELPKPELIRSLAP-------ASMVNAYG 2733
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T + + +PIGRP+ N +YLLD +P GE+++ GA
Sbjct: 2734 PTEATVCATIWTCPADFNGSV---VPIGRPIANTRVYLLDGHGAPVPFGAVGELYIGGAG 2790
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ A RF +P E RLYRTGD L G + + GR D QVKIRG+
Sbjct: 2791 VARGYLNRPELTAERFIASPFV---EGDRLYRTGDLARYLPDGNLEFLGRNDDQVKIRGY 2847
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP-------GARTSAQHIEG 426
R++ E+ L + V + VVL G+ ++ +V P G A +
Sbjct: 2848 RIEPGEIVARLCEHAWVREAVVLARQNGGGHKHLIAYVVCAPEAGSDEGGGGALAGALRA 2907
Query: 427 KLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L + L YM+P + + ++PL VNGK+DR L
Sbjct: 2908 HLSARLPDYMVPSAFVRLAALPLTVNGKLDRNAL 2941
>UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:
NRPS protein - Micromonospora sp. ML1
Length = 596
Score = 193 bits (470), Expect = 2e-47
Identities = 171/561 (30%), Positives = 261/561 (46%), Gaps = 48/561 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF- 78
++ LLA KAG AY+P++P +P R+ ++++DA P+L++ A S+ E GVP A
Sbjct: 66 MVVLLAVLKAGGAYLPLDPQYPAKRLAYMVQDARPTLLVR--MAQVSL--ELGVPVAELV 121
Query: 79 ---EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
+ A+E S + DA APL D++ V+YTSGSTG PKGV ++++ + + +
Sbjct: 122 VDDPDTARETESRPDHQLTDASRNAPLRPDNLMYVIYTSGSTGTPKGVAVTHTGVADIVA 181
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
Q + + + W +++F D+ W L A LI++ P +
Sbjct: 182 AQTASIAPRPGDRVLQW-ASVSF-DAAFWDWSAALLSGATLIMAPADELLPGQ------- 232
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
L TL R + + L P + + + G +S A G ++ N Y
Sbjct: 233 PLRDTLRRYAVTHAVLPPVALSVTEPDDVLVGGTLMSTGDACTRALVAKWAPGRRMYNGY 292
Query: 256 GSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
G TE +G + SD+ I IG P +Y+LDE L P + GE+++AG
Sbjct: 293 GPTETTVGSTIAGPIAISDE------ITIGTPWSGNRVYVLDERLRPVPNGRDGELYLAG 346
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIR 371
LA GY+ G A+RF +P P R+YR+GD G G +++A R D QVKIR
Sbjct: 347 NGLARGYLNRPGLTASRFVLDPFG--PPGGRMYRSGDRGHRRADGQLVFASRGDDQVKIR 404
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G RV+L EVE LA P VD V+ G D + FV+T G SA +
Sbjct: 405 GFRVELGEVEARLAAHPAVDVAAVVVVG-DLAGARLAAFVSTVAGTGVSAAELSAHSAET 463
Query: 432 LTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L +M+P ++V + +P+ NGK+DR L D AE A D +
Sbjct: 464 LPEHMVPSSVQVLQRLPVTANGKIDRAAL---------RDLAESAAHPDAAASAGPPGED 514
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSG--FYELGGNSLNSIYTITKLRDR-GYYVEISDFLG 547
+ +L R +R G F++LGG+S+ + +LRD G V I
Sbjct: 515 PTSVESRL-CLLVRELLAVPDVRPGDNFFKLGGHSVLATRLAGRLRDEWGITVPIRAVFE 573
Query: 548 ASTLGE----VLSKMSTDPNG 564
A+TL E V + ++ PNG
Sbjct: 574 AATLSELALVVQASKASIPNG 594
>UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase C - Brevibacillus texasporus
Length = 4617
Score = 193 bits (470), Expect = 2e-47
Identities = 139/445 (31%), Positives = 229/445 (51%), Gaps = 26/445 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AY+P++PS+P RIT++L+D++ L+I ++A + V + E
Sbjct: 1565 MIGILAILKAGGAYLPIDPSYPLERITYMLEDSQAQLLIVQEAAMIPEGYQGKVLLLAEE 1624
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
QE S+ + DA+ LA V+YTSGSTG PKG ++ I +
Sbjct: 1625 CWMQEEASN-LELINDAQDLA--------YVMYTSGSTGKPKGNLTTHQNILRTII--NN 1673
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV-LV 198
F + + + F S +I+ LL+G L+++ +E +P +L I R +
Sbjct: 1674 GFIEIVPADRLLQLSNYAFDGSTFDIYSALLNGATLVLVPKEVMLNPMELARIVREQDIT 1733
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + + L + + ++ ++ V GE S + + Y G +G +L N YG T
Sbjct: 1734 VSFMTTSLFHTLVELDVTSMKSIRKVVFGGEKASYKHVEKALDYLG--EG-RLVNGYGPT 1790
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T Y ++ S + +PIGRPL+N ++Y+L+E P PGE+ V GA +A
Sbjct: 1791 ETTVFATTYTVDSS--IKETGIVPIGRPLNNTSVYILNENNQPQPIGVPGELCVGGAGIA 1848
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF DNP R+YRTGD L G + Y GR D QVKIRGHR+
Sbjct: 1849 RGYLNRPELTAERFVDNPFLVG---DRMYRTGDMARFLPDGNIEYIGRMDEQVKIRGHRI 1905
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E++L + P + + V++ ++G+ + +V + + + + + AL Y
Sbjct: 1906 ELGEIEKSLLEYPAISEAVLVAKRDEQGHSYLCAYVVSTD--QWTVAKVRQHILEALPEY 1963
Query: 436 MMPQ-VIEVESIPLLVNGKVDRQGL 459
M+P +E+E +PL NGKVD++ L
Sbjct: 1964 MVPSYFVELEKLPLTSNGKVDKRAL 1988
Score = 183 bits (446), Expect = 1e-44
Identities = 151/546 (27%), Positives = 261/546 (47%), Gaps = 53/546 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +LA +KAG AY+P++PS+P RI ++L+D + L++ + V F + E
Sbjct: 530 IIGILAIFKAGGAYMPIDPSYPAERIQYMLQDNQTKLLLVQKQEMIPANYQGEVLFLTQE 589
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E TS+ A + ++A V+YTSGSTG PKG+ ++ I +
Sbjct: 590 SWMHEETSNPAHITQ---------AQALAYVMYTSGSTGEPKGILTTHQNI-------MK 633
Query: 140 TFPYSDSEEI----CVWKTA-LTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IE 193
T ++ EI C+ + + F S EI+G LLHG LL++++E + +L I+
Sbjct: 634 TVIHNGYVEITPGDCLSQLSNYAFDGSTFEIYGALLHGATLLLVTKEAVLNMNELARLIK 693
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ + + + + L + + ++ + GE S + + Y G +++ N
Sbjct: 694 KEQVTVSFMTTALFNTLVDLDITCFQSIRKVLFGGELASVKHVLKALDYLGE---HRVIN 750
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE TYY ++ S + ++PIGRP++N Y+++ + P GE+ +
Sbjct: 751 VYGPTETTVYATYYSVDHS--MLTRASVPIGRPINNTKAYIVNTDGQPQPIGVVGELCIG 808
Query: 314 GANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY+ + F DNP +R+Y TGD L G + Y GR D QVKI
Sbjct: 809 GEGVACGYLNRPELTKKHFVDNPFVLG---ERMYCTGDLARFLPDGNIEYIGRMDEQVKI 865
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RGHR++L E+E+ L Q P + + V+L ++G+ + ++ + + + L
Sbjct: 866 RGHRIELGEIEKVLLQHPAISETVLLAKRDEQGHSYLCAYIVGQ--VFWTVTELRQHLME 923
Query: 431 ALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
+L YM+P IE+E +PL NGKVD++ L E A VA + +
Sbjct: 924 SLPEYMVPSYFIEIEKLPLTANGKVDKRAL---PEPDRKMGSAYVAPENETEEKLVQFFQ 980
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEISDFLGA 548
+LG GT + F+ELGG+SL ++ + ++ ++ G V + +
Sbjct: 981 ----------EILGVERVGT---QDTFFELGGHSLKAMMLVLQIHKEMGIEVPLKEIFTR 1027
Query: 549 STLGEV 554
T+ E+
Sbjct: 1028 PTIKEL 1033
Score = 181 bits (441), Expect = 6e-44
Identities = 155/559 (27%), Positives = 267/559 (47%), Gaps = 44/559 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A KAG AY+P++PS+P RI H+L+D+ L+ + + V
Sbjct: 2600 MIGIFAILKAGGAYMPIDPSYPIDRIEHMLEDSRTKLLFVQKTEMIPASYQGEVLL---- 2655
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA+E H ++ L T D +A V+YTSGSTG PKG ++ I +
Sbjct: 2656 -LAEECWMHEDSSNLE---LINKTQD-LAYVMYTSGSTGKPKGNLTTHQNILTTII-NNG 2709
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV-LV 198
+ ++ + + + F S +I+ LL+G L+++ +E +P +L I R +
Sbjct: 2710 YIEIAPTDRL-LQLSNYAFDGSTFDIYSALLNGATLVLVPKEVMLNPMELAKIVREQDIT 2768
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + + L + + ++ ++ V GE S + + Y G +G +L N YG T
Sbjct: 2769 VSFMTTSLFHTLVELDVTSMKSMRKVVFGGEKASYKHVEKALDYLG--EG-RLVNGYGPT 2825
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T Y ++ S + +PIGRPL+N ++Y+L+E PGE+ V GA +A
Sbjct: 2826 ETTVFATTYTVDSS--IKETGIVPIGRPLNNTSVYVLNENNQLQPIGVPGELCVGGAGIA 2883
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +NP + R+YRTGD L G++ Y GR D QVK+RG+R+
Sbjct: 2884 RGYLNRPELTAERFVENPFVSG---DRMYRTGDLARWLPDGSMEYLGRMDEQVKVRGYRI 2940
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E L + P + V+L ++G+ + ++ G T A+ + L AL Y
Sbjct: 2941 ELGEIETRLLEHPSISAAVLLAKQDEQGHSYLCAYIVAN-GVWTVAE-LRKHLSEALPEY 2998
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P +E+E IP NGKV+++ L E VA + +
Sbjct: 2999 MVPTYFVELEQIPFTSNGKVNKRAL---PEPEGQMTSVYVAPETETEAKVAALFQ----- 3050
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEISDFLGASTLGE 553
+LG GT + F+ELGG+SL ++ + ++ ++ G V + + T+ E
Sbjct: 3051 -----EILGVERVGTQDM---FFELGGHSLKAMMLVLRMNKELGIEVPLKEVFAHPTVKE 3102
Query: 554 VLSKMS-TDPNGGADSKEA 571
+ + + D +G ++ + A
Sbjct: 3103 LAATIDLLDRSGHSEIEPA 3121
Score = 159 bits (385), Expect = 3e-37
Identities = 149/550 (27%), Positives = 243/550 (44%), Gaps = 55/550 (10%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSAD-PSMFKESGVPFAS 77
T++ ++ KAG AYVP++P +P R +IL+D+ SL+++ + PS F +
Sbjct: 3634 TVIGMMGILKAGGAYVPIDPDYPLDRKLYILEDSHASLLLFQQKHEVPSEFTGDRI---- 3689
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
L ++ + A D T+ +A ++YTSGSTG PKGV + + A+CN L
Sbjct: 3690 ---LIEQMQWYQA---ADTNVGIVNTAQDLAYMIYTSGSTGQPKGVMIDHQAVCN-LCLM 3742
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV---NIER 194
+T+ + + + + +F SV E++ L +G L ++ R + V +
Sbjct: 3743 AQTYGIFANSRVLQF-ASFSFDASVGEVFHTLTNGATLYLMDRNLLMAGVEFVEWLRVNE 3801
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ +P + S L L L LK GE L +L + +G E + N
Sbjct: 3802 ITSIPFISPSALRALPY----EDLPALKYISTGGEALPVDLV----RLWGTERIF--LNA 3851
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE D T + D+ P IG+P+ N Y+++ PGE+ + G
Sbjct: 3852 YGPTETTVDATIGLCTPEDK----P--HIGKPVLNKKAYIINPNYQLQPIGVPGELCIGG 3905
Query: 315 ANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIR 371
+A GY R F DNP A + +R+Y+TGD L G + + GR D QVKIR
Sbjct: 3906 VGIAPGYWNRPELTREKFVDNPFA---QGERMYKTGDLVRWLPDGNIEFLGRIDDQVKIR 3962
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
GHR++L E+E L + V + VVL ++G + ++ + + L
Sbjct: 3963 GHRIELGEIETRLLEHEQVIEAVVLAREDEQGQAYLCAYLVA--ADEWTVAELRKHLGKT 4020
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L YM+P IE+E PL +GKV+++ L D ++ ++
Sbjct: 4021 LPDYMIPAYFIELEEFPLTPSGKVNKKAL--------PEPDGQIQTGVEYVEATTESQKI 4072
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
V V + + F+ELGG+S+ +I +LR +EIS T
Sbjct: 4073 LVELWQEVLRV------ERIGIYDNFFELGGDSIKAIQITARLRRHHRKLEISHLFKHPT 4126
Query: 551 LGEVLSKMST 560
+ E+ M T
Sbjct: 4127 IAELAPWMQT 4136
>UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase F - Brevibacillus texasporus
Length = 2491
Score = 193 bits (470), Expect = 2e-47
Identities = 164/554 (29%), Positives = 272/554 (49%), Gaps = 58/554 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPS-LVIYDDSADPSMFKESGVPFASF 78
++ ++ T KAGAAY+P++PS+P+ RI H+L+D++ L+I P FK S V + +
Sbjct: 533 LVGVIGTLKAGAAYLPIDPSYPEKRIAHMLQDSKAEQLLIQPHLNMPQDFKGS-VLWLTE 591
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E A+E+T+ D P+ +++ +A ++YTSGSTG+PKGV + + A+ N + W
Sbjct: 592 ESWAKESTT---DLPLAT------SANDLAYMIYTSGSTGLPKGVMVEHQALVNLVMWHN 642
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERLVL 197
F + +++ C F SV E + PL+ G L +L D L E+ +
Sbjct: 643 EAFGVTMTDQ-CTKLAGFGFDASVWETFPPLIQGATLHVLEESRRGDIYALHEYFEKNAI 701
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ L + L + S LR L + G+ K E Y++ N YG
Sbjct: 702 TISFLPTQLAEQFMELTSSTLRVLLI---GGDRAQKV----------KETSYQIINNYGP 748
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T L + D++P IG+P+ N ++Y+LD+ PGE+ V+GA L
Sbjct: 749 TENTVVTTSGQLH--PEQDVFP---IGKPITNHSVYILDQNRHLQPIGIPGELCVSGAGL 803
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+ RF DNP +R+YRTGD + G++ Y GR D QVKIRG+R
Sbjct: 804 ARGYLNQPELTVERFVDNPFVPG---ERMYRTGDLVRWRIDGSIEYLGRIDEQVKIRGYR 860
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L + P + + +V+ ++G + +V GA S + L L
Sbjct: 861 IELGEIETKLLEHPSISEALVVARNDEQGYTYLCAYVVA-TGA-WSVSSLREHLIETLPE 918
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+P ++EVE +PL NGK+D++ L + + N+ A + +
Sbjct: 919 YMIPAYMMEVEKMPLTANGKIDKRA-LPVPDRQRMNEYVAPATETE------------EK 965
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKL-RDRGYYVEISDFLGASTLG 552
+LG GT + F+ELGG+SL ++ ++++ ++ G V++++ T+
Sbjct: 966 LVLLFQEILGLERIGT---KDHFFELGGHSLKAMMLVSRMHKELGVDVQLNEMFARPTVK 1022
Query: 553 EVLSKMSTDPNGGA 566
+ LS NG A
Sbjct: 1023 D-LSAYIDQMNGSA 1035
Score = 182 bits (442), Expect = 4e-44
Identities = 154/555 (27%), Positives = 260/555 (46%), Gaps = 51/555 (9%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
S I+ + KAG Y+P++P++P RI ++L+D++ L++ VP
Sbjct: 1554 SMIVGIFGIIKAGGGYLPIDPTYPTERIEYMLEDSQTHLLLVQH--------RDMVPAGY 1605
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSY----SAICNR 133
E+ S DE + L D +A V+YTSGSTG PKG ++ +CN
Sbjct: 1606 QGEVLIIEDEISRDEQVANIELINQPQD-LAYVMYTSGSTGKPKGNLTTHRNIIKTVCNN 1664
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
+ + T E+ + + F S +I+ LLHG L+++ +E +P L+ +
Sbjct: 1665 GYIEITT------EDRLLQLSNYAFDGSTFDIFSSLLHGATLVLVPKEVILNPTDLITLI 1718
Query: 194 RLVLVPTLLRSILMYLALGPAS-RPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
R + + ++ AL + ++ GE S + + + GN +L
Sbjct: 1719 REQQITVSFMTTSLFNALVELDVSSFQNMRKIAFGGEKASFKHVEKALDFLGNG---RLV 1775
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLL--DEELSPTRDSEPGEV 310
N YG TE T Y ++ +++ + IPIGRPL N +++L D++L P GE+
Sbjct: 1776 NGYGPTETTVFATTYTVD--ERIKEWGIIPIGRPLHNTTVHILSADDKLQPI--GVIGEL 1831
Query: 311 WVAGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQ 367
V+G LA GY+ RF +NP +P +R+YRTGD + VL Y GR D Q
Sbjct: 1832 CVSGEGLARGYLNLPELTMERFVENPF--RPG-ERMYRTGDLARWLPDGVLEYVGRKDEQ 1888
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VKIRGHR++L E+E + + P + + V+L ++G+ + ++ + + Q +
Sbjct: 1889 VKIRGHRIELSEIETRILEHPAISETVLLAKRNEQGSSYLCAYIVAH--GQWNIQELRKH 1946
Query: 428 LRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
+R L +M+P I ++ +PL NGKVD++ L + E ++ +
Sbjct: 1947 VRDVLPEHMVPSYFIGLDKLPLTSNGKVDKRAL----------PEPEGSLQL-TREIVAP 1995
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
V VLG A +S+ +ELGG+SL + + K+ + +E+ DF
Sbjct: 1996 RNESEKQLVEIVAEVLGLEA-SEISITDNLFELGGHSLTILRILAKVHTCNWKLEMKDFY 2054
Query: 547 GASTLGEVLSKMSTD 561
L E+ SK +TD
Sbjct: 2055 NCKNLEEIASK-ATD 2068
>UniRef50_Q1ER08 Cluster: Cereulide synthetase 1; n=6; Bacillus|Rep:
Cereulide synthetase 1 - Bacillus cereus
Length = 3391
Score = 193 bits (470), Expect = 2e-47
Identities = 158/559 (28%), Positives = 273/559 (48%), Gaps = 47/559 (8%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ +LA KAG AY+P++ ++P R ++L+++E ++++ + KES + F
Sbjct: 1852 FEMVVGILAVLKAGGAYLPIDTAYPMQRTEYVLQNSEATILLTKEC----YLKES-LDFE 1906
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+A D D + + T+ +A ++YTSGSTG PKGV +++ ++ N L
Sbjct: 1907 GEVFYLDDARLFEGDR-RDLQNINNPTN--LAYIIYTSGSTGNPKGVMVAHQSVVNLLLD 1963
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN----- 191
+P +E+ + KT TF SV EI+G G L+I +DP+KL+
Sbjct: 1964 LQEKYPVL-AEDKHLLKTTYTFDVSVAEIFGWFHAGGTLVIAGHGDEKDPEKLIQLIQCH 2022
Query: 192 -IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
+ + VP++L ++L L + + RLK + +GE +S EL + + + N K
Sbjct: 2023 KVTHINFVPSMLHAMLQALDEKDFAI-MNRLKYIIVAGEAVSPELCNRLYAHCPN---VK 2078
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDL-YPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
L N YG TE T Y S ++ +PIG+PL + Y+LD+ PGE
Sbjct: 2079 LENLYGPTEG----TIYATGFSIHKEMNVANVPIGKPLSHVETYILDQNNQIVPIGVPGE 2134
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
+ + G +A GY+ +F NP + +R+YRTGD L G + Y GR D
Sbjct: 2135 LCLGGICVAKGYMKEPVLTEEKFVVNP---MKQSERMYRTGDLVRWLADGNIEYLGRIDN 2191
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVKIRG R++L E+E A+A + V + +V +G +I+ +V ++ + + I
Sbjct: 2192 QVKIRGFRIELGEIEAAIAALEDVVQTIVTTMTDHKGANKIVAYVVSE---KYDEERIRE 2248
Query: 427 KLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXX 485
++ L YM+P + ++++PL NGKVDR+ L ++ D E ++D +
Sbjct: 2249 HVKKTLPQYMVPSYFVSMKALPLNKNGKVDRKQL-------HSVDLYETSMD---TVIVG 2298
Query: 486 XXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDF 545
+LG +S+ F++LGG+S+ +I I +++ + YY+
Sbjct: 2299 PRNEKEAMLSVIWQELLGLE---NISVHDNFFKLGGDSILAIQMIGRVKQQNYYLNPKQI 2355
Query: 546 LGASTLGEVLSKMSTDPNG 564
T+ E+ SK+ G
Sbjct: 2356 FQYQTIAELASKLQVQQVG 2374
Score = 41.5 bits (93), Expect = 0.084
Identities = 45/207 (21%), Positives = 79/207 (38%), Gaps = 21/207 (10%)
Query: 283 IGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQ 342
+GRP+ I ++DE+ + G + G + GY AN T+ +
Sbjct: 483 VGRPMPGIGIRIVDEDNQCLSEDRIGRFQIHGPTVMNGYFKNDEANA----ESFTEDGW- 537
Query: 343 RLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLD- 401
+ +GD G + G ++ GR + + G E+E + QVPGV+ V +
Sbjct: 538 --FDSGDLGFIHNGNLVITGRKKDMIVVHGANYYNYEIEALVEQVPGVETTFVCATSVKS 595
Query: 402 -RGNPE-------ILGFVTTKPGARTSAQHIEGKLRSALTHYMMPQVIEVESIPLLVNGK 453
G E ++ V+ + I + ++P I+ E+ +GK
Sbjct: 596 AEGAEELAIFFVPVINHVSVMFATMQQIKQIVARKMGITPKVIIP--IQKEAFFKTDSGK 653
Query: 454 VDRQGLLKMYENTNNNDDAEVAVDIDC 480
+ R K +E N E+ IDC
Sbjct: 654 ITRNAFQKQFE---NGAYREITQKIDC 677
Score = 37.1 bits (82), Expect = 1.8
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
Query: 83 QEATSHSADEPMDAE---TLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
QE HS + MD P T D+I + L TSGSTG+PK V+ +I R
Sbjct: 246 QEIVIHSIENVMDTARDTNWFPCTEDTIVLNLLTSGSTGVPKCVQHKSKSIIAR 299
>UniRef50_Q0RI59 Cluster: Non-ribosomal peptide synthetase; n=3;
cellular organisms|Rep: Non-ribosomal peptide synthetase
- Frankia alni (strain ACN14a)
Length = 1531
Score = 193 bits (470), Expect = 2e-47
Identities = 161/557 (28%), Positives = 257/557 (46%), Gaps = 34/557 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYD---DSADPSMFKESGVPFA 76
++A+LA +AGA+YVP++P +P R+ +L D+ P L++ A P++ V
Sbjct: 503 VVAVLAVARAGASYVPVDPDYPPDRVRLMLTDSRPVLLLTTAAGQGALPAVDGLRAVLLD 562
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ + LA+ D DAE +APL + A V+YTSGSTG+PKGV +++ A+ N L W
Sbjct: 563 AADTLARLGALPDHDLT-DAELVAPLHPEHPAYVIYTSGSTGVPKGVVVAHRALANHLDW 621
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
FP + ++++F SV + L G A+ + + + L
Sbjct: 622 AVARFPGLAGHTLM--HSSISFDFSVTPLLATLTCGGAVELCADSPDAIARAAGAATFLK 679
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ P+ L + R L V +GE L E ++ +D + + N YG
Sbjct: 680 ITPSHLPLLASVRFADDGPRTL------VIAGEELRGEALDQWKWRRPADDRFAVINEYG 733
Query: 257 STEV-MGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
TE +G + + V D +P+G P+ N ++LDE L PGE+++ GA
Sbjct: 734 PTETTVGALLHPVDAAPDGTGTVGAVPVGSPVANTTCHVLDENLRLAPLGVPGELYIGGA 793
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRG 372
LA GY+ G A+RF +P+ P RLYRTGD L GA+ + GR D QVKIRG
Sbjct: 794 QLARGYLNRPGLSASRFVADPYG--PPGARLYRTGDLMRRLPSGALQFLGRVDDQVKIRG 851
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
HRV+L E+E L PGV + V G + ++ GA+ A + + L
Sbjct: 852 HRVELGEIESVLLAAPGVAQATVAARTDGPGGRYLAAYLVLADGAQPDAAALRAHAAATL 911
Query: 433 THYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
+M+P + + ++PL +GKVDR+ L A+ A S
Sbjct: 912 PDHMVPATLTFLPALPLSPSGKVDRRAL------PAPRFGADPAA---ASPARPPASGAE 962
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYV---EISDFLGA 548
+LG ++ L + F+ELGG+S+ +I +++ R G E+
Sbjct: 963 TTLAALFADILGVE---SVRLDTSFFELGGDSILAIRLVSRARREGLPFTPREVFAHRTV 1019
Query: 549 STLGEVLSKMSTDPNGG 565
+L + + TD +GG
Sbjct: 1020 ESLAAAATTVVTDADGG 1036
>UniRef50_A0V6U0 Cluster: Amino acid adenylation domain; n=1; Delftia
acidovorans SPH-1|Rep: Amino acid adenylation domain -
Delftia acidovorans SPH-1
Length = 2149
Score = 193 bits (470), Expect = 2e-47
Identities = 169/568 (29%), Positives = 267/568 (47%), Gaps = 45/568 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++P +P R+ H+++D+ +LV+ + +P A+
Sbjct: 493 VVGLLAILKAGGAYVPLDPDYPADRLAHMVEDSGIALVLTQAAV------RERIPGAAAL 546
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ + + EP + +++DS+A V+YTSGSTG PKG +LS+ + L
Sbjct: 547 QVLEIDMLDLSGEP-GTDPQVEVSADSLAYVIYTSGSTGRPKGAQLSHRNVARLLDATDA 605
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIERLV 196
F + +++ + F SV EI+G L G L+++ +R PQ L+ ER+
Sbjct: 606 WFGFG-PDDVWTLFHSYAFDFSVWEIFGALCTGGRLVVVPYWVSRSPQDFLALLRAERVT 664
Query: 197 LV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
++ P+ ++ + + L+ + GE L E +F FG++ +L N
Sbjct: 665 VLNQTPSAFGQLVHAVEQEDGNGAGLALRQVIFGGEALEPESLRPWFDRFGDQSP-QLIN 723
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTY + +D LD P+G + + +Y+LD L+ GE++VA
Sbjct: 724 MYGITETTVHVTYRQITKAD-LD-GGRSPVGVAIPDLGLYVLDGSLNLLPQGVAGELYVA 781
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKI 370
G LA GY+ G A RF NP TQ RLYRTGD +G + Y GR D QVKI
Sbjct: 782 GEGLARGYLNRAGLSAERFIANPF-TQAG-DRLYRTGDLVRWSAQGELEYLGRADQQVKI 839
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L EV+ L P V + VVL + ++ +V+ + S ++ +L
Sbjct: 840 RGFRIELGEVQSQLLAQPEVREAVVLA----KEGARLIAYVSLRDAVEES--QLKQRLGQ 893
Query: 431 ALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
AL YM+P I V E++PL NGKVDR+ L + E+ I
Sbjct: 894 ALPDYMVPSAIVVLEALPLTANGKVDRKAL----------PEPEM---ISAQQYEAPQGE 940
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
VLG G + GF+ELGG+SL ++ + ++R +G V++
Sbjct: 941 LEETLATIWAEVLGVDRVGR---QDGFFELGGHSLLALGLLERVRAQGLRVQVRTLFQHP 997
Query: 550 TLGEVLSKMSTDPNGGADSKEATFTAVP 577
L E + G + A VP
Sbjct: 998 RLAEFAQAVLQAQQGDQGEQVAGEIDVP 1025
Score = 163 bits (395), Expect = 2e-38
Identities = 169/578 (29%), Positives = 248/578 (42%), Gaps = 61/578 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ LLA KAGAAYVP++P+ P R+ ++L+D+ LV+ A P
Sbjct: 1580 VAGLLAILKAGAAYVPVDPALPDERMQYMLQDSGACLVLASGLA-PGRLAVLAASVPKVL 1638
Query: 80 EL-AQEATSHSADEPMDAETLAP---LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
EL A E P AP + D A V+YTSGSTG PKGV + ++A N L
Sbjct: 1639 ELEALEVLEAREPGPQAGSERAPRVEVHGDQAAYVIYTSGSTGRPKGVVVRHAAFSNFLQ 1698
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--- 192
P ++++ + T+++F + EI+ PL G L++ RE RD L +
Sbjct: 1699 -SMAAQPGLQAQDVVLATTSVSFDIAGLEIFLPLAVGAQLVVAGREQVRDAAALAALLER 1757
Query: 193 ERLVLVPTLLRSILMYLALG-PASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
R ++ + LA G A+RPL+ L C GE L+ +L G L
Sbjct: 1758 SRASVMQATPSGWRLLLAGGWKAARPLKAL----CGGEALAPDLIDLL-----RAAGVDL 1808
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE + ++G +G+ + + +LDE L GE++
Sbjct: 1809 WNLYGPTETTIWSSLQQVQGD-------AATLGQAIAATRLLVLDEGLRCVPQGVAGELF 1861
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEF-QRLYRTGDFGTL-VKGAVLYAGRTDAQ 367
+ G LA GY G A RF +P A +RLYRTGD GA+ Y GR D Q
Sbjct: 1862 IGGQGLARGYWQRPGLSAERFVADPFAGPGAAGERLYRTGDLVRRNADGALEYLGRLDHQ 1921
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS------- 420
VKIRGHR++L EVE AL P V + VV G + ++ V+ S
Sbjct: 1922 VKIRGHRIELGEVEAALLAQPEVREAVVTAAG-SGSDTRLVAHVSLHASLHASLHAPLHA 1980
Query: 421 -----AQHIEGKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEV 474
A + +L S L YM+P I V +++PL +GKVDR L + +A
Sbjct: 1981 GPPLDAAALRARLASGLPDYMLPSAIVVLDTLPLNNSGKVDRAALPAAQAPAGQSYEAP- 2039
Query: 475 AVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR 534
+LG G + R F+E GG+SL + + +L+
Sbjct: 2040 ------------SGQAEEMLAGLWSELLG---GGRVDRRDSFFERGGHSLKVVQLLARLQ 2084
Query: 535 DRGYY-VEISDFLGASTLGEVLSKMSTDPNGGADSKEA 571
G + D L ++ + +GGAD+ A
Sbjct: 2085 GAGAAGLTAQDIFRTPVLQDMAGLVRLPAHGGADAAGA 2122
>UniRef50_A1FGJ4 Cluster: Amino acid adenylation; n=1; Pseudomonas
putida W619|Rep: Amino acid adenylation - Pseudomonas
putida W619
Length = 2845
Score = 192 bits (469), Expect = 2e-47
Identities = 145/451 (32%), Positives = 222/451 (49%), Gaps = 39/451 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++P +P R+ ++++D+ SL++ + +P +
Sbjct: 568 VVGLLAILKAGGAYVPLDPEYPAERLRYMVEDSGISLLLTQSHLRDRLPLPPRLPVLLLD 627
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ H P AP + +A V+YTSGSTG PKG S+ A+ NRL W
Sbjct: 628 QALAAQPEHDPQLPC-----AP---EQLAYVIYTSGSTGRPKGAGNSHQALANRLQWMQA 679
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+ D+ + + KT +F SV E + PL+ G L I + RDP +LV +
Sbjct: 680 AYGL-DASDTVLQKTPFSFDVSVWEFFWPLITGARLAIAAPGDHRDPARLVQLIVQHQVT 738
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP++L++ L+ + S L+R+ VCSGE L E + F +L N
Sbjct: 739 TLHFVPSMLQAFLLDDQVARCS-SLQRI---VCSGEALPVEAQQQVFAQLPQA---RLYN 791
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT++ + +PIG+P+ N A ++LD L P GE+++
Sbjct: 792 LYGPTEAAIDVTHWTCRDEGKTG----VPIGKPIANLACWILDAGLQPQPAGVIGELYLG 847
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G LA GY A RF P QP R+YRTGD G + Y GR D QVKI
Sbjct: 848 GVGLARGYHQRPALTAERFVACPF--QPG-ARMYRTGDLARYRADGVIEYCGRIDHQVKI 904
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLR 429
RG R++L E+E L + P + + VL + +++ ++ K G + + L
Sbjct: 905 RGLRIELGEIEARLMEQPTIHEAAVLAV-----DNQLVAYLVAKAGTPLPEREQLSQALL 959
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L YM+P Q + ++ +PL NGK+DR+ L
Sbjct: 960 AHLPDYMVPNQWLFLQRMPLSPNGKLDRKAL 990
Score = 147 bits (356), Expect = 1e-33
Identities = 152/553 (27%), Positives = 252/553 (45%), Gaps = 60/553 (10%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
TI+A A KAGAAYVP++ +P R+ I+ DA+ +L++ D + + G+
Sbjct: 2058 TIVAFYAVMKAGAAYVPLDIDYPAERLQWIIGDADVALLL----TDSVIGERLGIAPERR 2113
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAI---CNRLW 135
+L + S P +TL D ++ ++YTSGSTG PKGV ++ + C +
Sbjct: 2114 LDLDRCELSAQRHAPQQ-QTL----DDQLSYMIYTSGSTGNPKGVAVARGPLRMHCQAII 2168
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK---LVNI 192
++ P + E+ A D E W L LL+L T PQ+ +++
Sbjct: 2169 ERYEMGP--STRELLFMSFAF---DGAQERWLSTLISGGLLVLRGNTLWTPQQTWDVLHA 2223
Query: 193 ERLVLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
E + + P L+ + Y PA P+R ++ G+ ++ + + +
Sbjct: 2224 EAISIACFPPAYLQQLAEYGQAQPAPPPVR---IYCFGGDAVADANFEQVKQVLKPQ--- 2277
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
L N YG TE + + + + + + PIG + +Y+LD+ L+P GE
Sbjct: 2278 YLTNGYGPTETVVTPLLWKVPVTARCEAV-YAPIGVAVGKRTLYVLDDCLNPLPAGLAGE 2336
Query: 310 VWVAGANLAAGY--VGGGGANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDA 366
+++ G LA GY G A RF +P + RLYRTGD G Y GR D
Sbjct: 2337 LYIGGEGLARGYHRRPGLSAERFVADPFSATG--GRLYRTGDLVRQRPDGVFDYLGRLDN 2394
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVK+RG R++L E+E L + V VV+ G +++G+V G R +E
Sbjct: 2395 QVKVRGFRIELGEIEARLRDIANVLDAVVVAREGANGK-QLVGYVVRGDGERAVTPMLE- 2452
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXX 485
LR L YM+P Q++ ++++PL NGKVDR+ L + + C
Sbjct: 2453 YLRQVLPDYMVPAQLMVLDALPLTPNGKVDRRALPE---------------PLMCERQYQ 2497
Query: 486 XXXXXXXXXXXTVGA-VLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR---GYYVE 541
+ A VLG G + F+ELGG+SL+ + +++LR++ G ++
Sbjct: 2498 APADDRQRALAAIWADVLGLEQVG---VSDHFFELGGDSLSVLKVLSRLRNQPQLGLNLK 2554
Query: 542 ISDFLGASTLGEV 554
+ D + T+ E+
Sbjct: 2555 LRDLIARPTIAEL 2567
>UniRef50_Q81DB7 Cluster: Peptide synthetase; n=4; Bacillus cereus
group|Rep: Peptide synthetase - Bacillus cereus (strain
ATCC 14579 / DSM 31)
Length = 2156
Score = 192 bits (467), Expect = 4e-47
Identities = 152/572 (26%), Positives = 274/572 (47%), Gaps = 45/572 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL K+GAAYVP++P++P+ R+ +IL+DA +++ ++++ E+ E
Sbjct: 525 MIALLGILKSGAAYVPLDPTYPESRLRYILEDAGIEVLVTEENSKNLFVSEN------IE 578
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + ++ ++ +T +++A V+YTSGSTG PKGV + + ++ N L W
Sbjct: 579 TICMNKDYTAIEKEETTPCISGVTGENLAYVMYTSGSTGNPKGVMIEHHSVINYLEWMQH 638
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER----- 194
+P S+ +++ + KT +F SV E++ + G ++ L +DP + + +
Sbjct: 639 KYPLSE-KDVVLQKTPFSFDVSVWELFWGIHVGASVSFLPPGGEKDPSIIAEVIKQHQVT 697
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP++L L + + ++ GE LS L F + + KL N
Sbjct: 698 IVQFVPSMLSVFLDHFNHIELNMNCSSVRHVFSGGEELSSGLVRRFQQKWDYSGQVKLTN 757
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
FYG TE V + ++ + + + IG+P+ N +Y+LD+ GE+++
Sbjct: 758 FYGPTEATIYVNAFDIQPNQEF-----VSIGQPIQNTQLYVLDQNQRLQSIGIEGELYIG 812
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKI 370
GA LA GY+ A +F +P+ +RLYRTGD L G + + GR D QVK+
Sbjct: 813 GAGLARGYLNRPNLTAEKFVSHPYRFG---ERLYRTGDSVRYLTDGNLEFIGRMDHQVKM 869
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L + + + VVL G+ ++ +V + + ++++ +L
Sbjct: 870 RGFRIELGEIEATLEKCSFIKEAVVLVREDRPGDQRLVAYVISDGNTQEWREYLQKQLP- 928
Query: 431 ALTHYMMPQVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
TH + IE+E PL NGK+DR+ L D +V D++
Sbjct: 929 --THMIPAHFIELEHFPLTPNGKIDRKAL--------PAPDEQVIEDLN----VLPRTPS 974
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGAS 549
G VLG +S++ F+E GG+SL + +++L++ + + +
Sbjct: 975 EELIASVWGQVLGIE---NISIQDSFFERGGHSLLATQIVSRLQELFQIKIPLRELFKHD 1031
Query: 550 TLGEVLSKMSTDPNGGADSKEATFTAVPMRDE 581
T+ E L+K D D K VPM+ E
Sbjct: 1032 TV-EALAK-RVDQLRKEDKKREVAPLVPMKRE 1061
Score = 179 bits (436), Expect = 2e-43
Identities = 127/444 (28%), Positives = 219/444 (49%), Gaps = 29/444 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAG AYVP++P++P+ R+ +IL+D + +++ + M V +
Sbjct: 1586 IVGLLGIMKAGGAYVPIDPAYPESRLQYILEDTQIKVLVTQEKLQQKMVIPKFVDVICID 1645
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E ++ + ++ +T D++A ++YTSGSTG PKGV + + + W R
Sbjct: 1646 RNRAE-----IEQEVTTVCMSEVTGDNLAYIIYTSGSTGNPKGVMIEHRNTVTMIHWAHR 1700
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T+ + + T+L+F SV E++ PL G +++ + + + VP
Sbjct: 1701 TYSRKELAGVLA-STSLSFDLSVFELFVPLTMGGKVIVTENALHLEKLSTKGVTLVNTVP 1759
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
++ + ++ + P+S +K+ +GE L L + ++ E K+ N YG +E
Sbjct: 1760 SVAKELVRVKTI-PSS-----VKVMNLAGEPLPYSLVQDLYERSTIE---KVYNLYGPSE 1810
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
D TY ++ +Y PIG+P+ N +Y+L E GE+++ G+ LA
Sbjct: 1811 ---DTTYSTYMELEKGVMYRVPPIGKPIFNTEVYVLSAEQKMVPIGVVGELYIGGSGLAR 1867
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ N F +P E +R+YRTGD L G + Y GR D QVKIRG R++
Sbjct: 1868 GYLNRPDLTQNLFISHPF---KEGERVYRTGDLVRYLPDGNLEYVGRIDHQVKIRGFRIE 1924
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L E+E AL + V++ +V+ G+P ++ +V AQ L+ L +YM
Sbjct: 1925 LGEIEAALQRHILVNEAIVMVREDYPGDPRLIAYVV----GDGDAQKWRDYLKDQLPNYM 1980
Query: 437 MPQ-VIEVESIPLLVNGKVDRQGL 459
+P + + + PL NGK+DR+ L
Sbjct: 1981 IPSYFVGLNAFPLTPNGKIDRKAL 2004
>UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide
synthetase; n=1; Bacillus cereus E33L|Rep:
Multifunctional nonribosomal peptide synthetase -
Bacillus cereus (strain ZK / E33L)
Length = 3044
Score = 192 bits (467), Expect = 4e-47
Identities = 157/546 (28%), Positives = 268/546 (49%), Gaps = 53/546 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAE-PSLVIYDDSADPSMFKESGVPFA-S 77
I A+L KAGAAY+P++PS P R+++I+KD++ +L+ ++ + + E + S
Sbjct: 513 IAAVLGALKAGAAYLPIDPSMPLERLSYIIKDSKMDALITSQENFEITDLSEDNIFLLNS 572
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E ++ A +A T +S+A V+YTSGSTG PKGV ++ I N+ +W
Sbjct: 573 LEGMSATAPRRTA------------TKNSLAYVIYTSGSTGNPKGVMITNENIVNQAYWH 620
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ER 194
++ + TA F S EI+ LL G LL++ E ++P++L+ +
Sbjct: 621 ITEAELTNKSRY-IQNTAFIFDGSALEIFSTLLSGAQLLLVDSEKKKEPEELLKLLPGAH 679
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ ++P++ R+++ Y L + E + EL ++ G++ KL N
Sbjct: 680 INILPSMFRALVEYAIDNKKEEALNSFERLNLVAEKIPGELIGKYNSTKGSKLS-KLWNL 738
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE T Y L ++ ++L IPIG+P+ N +Y+L + GE+ ++G
Sbjct: 739 YGPTEATITSTSYQL--NENMNLV-NIPIGKPVSNYKVYILHKN-DLCAQGILGEICISG 794
Query: 315 ANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
+A GY+ F P T + +YRTGD G + G V GR D QVKIR
Sbjct: 795 RGVAKGYLNNSKLTEEVFIRCPAITD---EVIYRTGDIGFINPDGEVELVGRMDEQVKIR 851
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G RV+L E+E L V GV + VV+ + + FV K + + I+ L +
Sbjct: 852 GFRVELQEIESTLKGVEGVKEAVVVRQKNLNDDFLVAYFVGDK---KVNDLIIKDNLSNR 908
Query: 432 LTHYMMPQ-VIEVESIPLLVNGKVDRQ--GLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
L YM+P+ +I ++ IPLL NGK++++ G LK+ + + + + C
Sbjct: 909 LPEYMVPEFIIRLDEIPLLPNGKINKKLLGELKLNKLSKFEEPRNPIEEDLCD------- 961
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
VLG +S+ + F+ELGG+S+ +I ++KLR++GY + + +
Sbjct: 962 --------VFSIVLGFE---KISVNTSFFELGGDSIKAIRIVSKLREKGYSSTVKNIMQY 1010
Query: 549 STLGEV 554
T+ ++
Sbjct: 1011 KTVQKI 1016
Score = 171 bits (415), Expect = 8e-41
Identities = 136/450 (30%), Positives = 224/450 (49%), Gaps = 28/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+ A KAGAAY+P++P P R+ ++LKD++ L+I + + + F + E
Sbjct: 2010 IIAIYAILKAGAAYLPIDPKQPLDRVKYMLKDSKAKLIIAGTNGEKLVTGLEDFQFINVE 2069
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E ++ P+ T +P SD +A ++YTSG+TG PKGV + + N W
Sbjct: 2070 DNLGELENNL---PI---TASP--SD-LAYIIYTSGTTGKPKGVMIENQNVVNLATWLIS 2120
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV---NIERLV 196
D + + F SV EI+ L G LLI+S E +P++++ N +V
Sbjct: 2121 HLKL-DEFSTMIQNFSFIFDGSVWEIFPTNLAGSRLLIVSDEQKVNPKEMIRNFNNAHVV 2179
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYF-GNEDGYKLANFY 255
+VP++ R +L Y + L LK +GE + +L SEFFK G ++ ++ N Y
Sbjct: 2180 MVPSMYRELLEYAKMNGILYKLHALKSISLAGEAMPLDLISEFFKTSKGIKNKPRIQNCY 2239
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T Y + D D + +G+P+ N + ++++E GE++V G
Sbjct: 2240 GPTEATVCSTVYEFK-EDVND--SRVLVGKPILNTSAFIMNEN-KLVGIGMIGELFVGGH 2295
Query: 316 NLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
+A GY+ +F D+P+ E + LY+TGD G + GR QVKIRG
Sbjct: 2296 GVATGYLNNEKLSKEKFVDHPY---EEGEVLYQTGDLARWNADGNIELFGRIGEQVKIRG 2352
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+E + QV + VV+ DR +I+ + T + ++ L L
Sbjct: 2353 FRIELGEIESYIRQVKDITDSVVVLDTNDR-TEKIVAYFTAR--KEIDISRLKELLSKKL 2409
Query: 433 THYMMPQ-VIEVESIPLLVNGKVDRQGLLK 461
YM+P+ I++ IP +NGK+D++ L K
Sbjct: 2410 NDYMVPEHFIQLAGIPKTINGKIDKRNLPK 2439
>UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1;
Burkholderia thailandensis E264|Rep: Peptide synthetase,
putative - Burkholderia thailandensis (strain E264 / ATCC
700388 / DSM 13276 /CIP 106301)
Length = 3650
Score = 192 bits (467), Expect = 4e-47
Identities = 167/552 (30%), Positives = 251/552 (45%), Gaps = 42/552 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDS-ADPSMFKESGVPFASF 78
++ LLA KAG AYVP++P++P R+ ++L DA P+ V+ + AD FK +P
Sbjct: 584 VVGLLAVLKAGGAYVPLDPAYPAARLAYMLDDAAPAAVLTTAALADELAFK---LPTILL 640
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ S D P D L LTS +A V+YTSGSTG PKGV + + + N +
Sbjct: 641 DAQNPSFESQPNDNP-DPAALG-LTSRHLAYVIYTSGSTGQPKGVMVEHGNLVNLIQSNR 698
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP----QKLV--NI 192
+ F C W T+ F V EI+ L G + ++ Q L+ I
Sbjct: 699 QHFSGVGQARTCCW-TSFGFDVCVFEIFMSLAMGGTVHVVPDRLRISADGFFQWLIAQRI 757
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
E L P L+R + Y AS LRR+ + V E L ++ + ++ +
Sbjct: 758 EVAYLPPFLVRRLREYSDELVASLSLRRILVGV---EPLREK---DLYRLERLLPELIVV 811
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE T Y+ D D PIGRP+ N IY+LD P GE+ +
Sbjct: 812 NGYGPTETTVFSTSYL----DMRDYDRAAPIGRPIANTRIYILDSHGQPVPIGVAGEIHI 867
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
AGA +A GY+ A RF + A P R+YRTGD G L G + Y GR D QVK
Sbjct: 868 AGAGVARGYLNRPELTAERFVSDSFAAAPN-ARMYRTGDLGRWLPDGTIEYLGRNDFQVK 926
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG R++L E+E LA+ GV VV+ G+ ++ +V + G + +L
Sbjct: 927 IRGLRIELGEIEARLARCDGVRDAVVIAREDTPGDKRLVAYVLPQSGVALVPAELRRQLA 986
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
L +M+P + ++++PL NGK+DR+ L + A V+ +
Sbjct: 987 GQLAEHMLPSAFVMLDALPLTPNGKLDRKAL------PAPDQTAVVSRGYEAPTGEVETA 1040
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
+GR F+ELGG+S+ + I +LRD G+ +++ A
Sbjct: 1041 LARIWQDLLGLEQVGR--------HDHFFELGGHSMLVVSMIERLRDLGWSLDVRSMFVA 1092
Query: 549 STLGEVLSKMST 560
L ++ + T
Sbjct: 1093 PVLADLAQAIDT 1104
Score = 162 bits (393), Expect = 4e-38
Identities = 151/550 (27%), Positives = 252/550 (45%), Gaps = 61/550 (11%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I A +AG AYVP++P+ P R+ +L A + V+ + ++ G+
Sbjct: 1665 IAAYSGVMRAGCAYVPIDPATPPERMRDVL--ATLNYVLTTRALAAAL---DGI------ 1713
Query: 80 ELAQEATSHSADEPMDAETLAPLTS-DSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+A DE A+ P + D +A V++TSGSTG PKGV + + A +
Sbjct: 1714 ----DARVILVDEAAAADVAPPTVALDDLAYVMFTSGSTGKPKGVMIDHRAASLTIESIL 1769
Query: 139 RTFPYSDSEEI-CVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIER 194
R + ++ + CV +++ F SV + +G G A+++ + +P L+ ER
Sbjct: 1770 RRYAIGPADRLLCV--SSVGFDLSVFDFFGAFAAGAAVVLAPESSNVEPHVWLDLMERER 1827
Query: 195 LVL---VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ VP ++ +L+ P LKL + SG+ + L + + + + +
Sbjct: 1828 ATVWESVPAVMELLLLECRNSGRKLP-PSLKLVMLSGDRVPVSLPARI-REAATAELHVI 1885
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPT---IPIGRPLDNCAIYLLDEELSPTRDSEPG 308
A G+TE YY D L P +P GR L +Y+L L P PG
Sbjct: 1886 A-LGGATEAAIWSCYY-----DTRHLPPDASFVPYGRHLPGQRLYVLSSSLRPLPIGVPG 1939
Query: 309 EVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTD 365
++W+AGA +A GY+G A RF +PH +R+YRTGD L G + + GR D
Sbjct: 1940 DLWIAGAGVARGYLGQPDLTAYRFVADPHVPG---ERMYRTGDRARVLADGNLEFLGRVD 1996
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
QVKIRG R+++ E+E AL PGV++ V G I +V + A I
Sbjct: 1997 DQVKIRGFRIEIGEIEAALGAAPGVERGVATIVE-HHGRQTIAAYVVARANAVLDHAEIR 2055
Query: 426 GKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXX 484
L L YM+P ++ ++S+PL NGK+DR+ L+++ + + V+
Sbjct: 2056 DALARRLPPYMLPASIVSIDSVPLTRNGKIDRRALMQVRAPASPAEGPRNVVE------- 2108
Query: 485 XXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISD 544
AVLGR A + + F++ GG+S+ +I +T+ R++ ++ D
Sbjct: 2109 -------KALASIWQAVLGREA---IDVHENFFDAGGDSMLAIRIVTRAREQRIHIMPRD 2158
Query: 545 FLGASTLGEV 554
L T+ ++
Sbjct: 2159 VLQLQTIAKI 2168
Score = 162 bits (393), Expect = 4e-38
Identities = 141/449 (31%), Positives = 212/449 (47%), Gaps = 43/449 (9%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
TI A+ +GAAYVP++P +P R +++DA+P +VI A ++
Sbjct: 3116 TIAAMYGILASGAAYVPLDPDWPDERKALVIEDAQPLMVIGGGGAWCGAVRQ-------- 3167
Query: 79 EELAQ-EATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
ELA+ + T +A P A T D +A V+YTSGSTG PKGV + + + + +
Sbjct: 3168 VELAELDVTPDAALTPHQA------TVDDLAYVIYTSGSTGRPKGVMVRHGDVMHLDGLR 3221
Query: 138 FRTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
R S+++ VW + F S+ EIW PL+ G ++ + TR P+ + R
Sbjct: 3222 ER-MALSETD---VWTAFHSYAFDYSILEIWYPLMTGATVVPVPYWVTRSPEAFHELLRT 3277
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY-KLANF 254
+ ++ + L RL+ V GET L + + Y ++AN
Sbjct: 3278 EGATIVCQTPAAFQQLVAVPHRGVRLRWAVVGGETYHASLPAS-----ADPAQYPRIANV 3332
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE T+ LE + IGRP IYLLD GE+ VAG
Sbjct: 3333 YGITETTVITTFEPLERGQ------PVTIGRPFPGQRIYLLDRHGRLVPPGAVGEIHVAG 3386
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYA-GRTDAQVKIR 371
+AAGY+G A RF +P+ +P +R+YR+GD G + G + + GR D QVKIR
Sbjct: 3387 EGIAAGYLGAQALTAQRFVADPY--RPG-ERMYRSGDLGRFLPGGRMESLGRADRQVKIR 3443
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G+R++L E+E AL+ + G+ V G + +V A AQ + L+
Sbjct: 3444 GYRIELGEIECALSSLEGIGGAVADVREGASGRQLVAWYVA---AADMDAQRVRTALKQR 3500
Query: 432 LTHYMMPQ-VIEVESIPLLVNGKVDRQGL 459
L MMP +I V+ L NGK+DR+ L
Sbjct: 3501 LPDSMMPSALIRVDGFALTANGKIDRRAL 3529
>UniRef50_Q70JX4 Cluster: FenD protein; n=18; Bacillus|Rep: FenD
protein - Bacillus amyloliquefaciens
Length = 3605
Score = 192 bits (467), Expect = 4e-47
Identities = 146/552 (26%), Positives = 265/552 (48%), Gaps = 52/552 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+ WKAG AYVP++P +P+ R +I+ D+ +L++ A + + E
Sbjct: 2604 VAAVFGVWKAGGAYVPIDPEYPEERKQYIISDSGTALLLTAHGAIEQVPDRFNGEVLALE 2663
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ ++ S P+ + + AP + +A ++YTSG+TG PKGV + + ++ L W+
Sbjct: 2664 DIQEQDAS-----PVQSLS-AP---EDLAYIIYTSGTTGRPKGVMVEHRSVSQTLQWRSG 2714
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
+ ++ + I + + +F V ++ PL+ G +L+ + RD + + I
Sbjct: 2715 FYDLNEKDTI-LQLFSFSFDGFVTSMFTPLISGAKAAVLAEDEARDILAIKHYLASYRIT 2773
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+++VP L R++L L G A L++ +GE + + + S + + LAN
Sbjct: 2774 HMIIVPVLYRTLLDVLEPGDAES----LRIVTLAGEAVDQNIISRSLSVCPHTE---LAN 2826
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T + ++ I IGRP+++ +Y+L+ + P GE+ ++
Sbjct: 2827 EYGPTENSVATT-----AARHIEQSENITIGRPIEHSHVYILNGD-HPQPIGVTGELCIS 2880
Query: 314 GANLAAGY--VGGGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G+ LA GY + A F +P +R+YRTGD L G + Y GR D QVKI
Sbjct: 2881 GSGLARGYRNLPKQTAQAFVQDPFQKN---RRMYRTGDLAKWLPDGTLQYIGRIDEQVKI 2937
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG+RV+L E+E AL + GV + V + G E+ ++ T+ G T ++ ++ LR+
Sbjct: 2938 RGYRVELKEIESALTGIKGVKEAAVTAHTASAGQTELCAYIVTEEG--TESETVQQALRN 2995
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
+ YM+P E +E++P+ NGK+DR+ L + + + A + D
Sbjct: 2996 EMPAYMVPAFFETLEALPVTPNGKLDRRALPEPRKKAHTG-QAFTEPESDMEKELSAIW- 3053
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
VLG ++ F+ELGG+S+ ++ +L G + + D
Sbjct: 3054 ---------SEVLGTE---NIAADKSFFELGGDSIKALQVSARLHQAGKQIAVKDIFSRP 3101
Query: 550 TLGEVLSKMSTD 561
T+ E+ + T+
Sbjct: 3102 TIRELAPYVRTE 3113
Score = 180 bits (438), Expect = 1e-43
Identities = 131/454 (28%), Positives = 229/454 (50%), Gaps = 42/454 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSA-DPSMFKESGVPFASF 78
++ + A KAG AY+P++P +P+ RI +LKD+ ++ + P +F+ + S
Sbjct: 1573 LIGIYAVLKAGGAYLPIDPDYPEERIRFLLKDSGVKFLLAEPELFAPDLFEGETISLKS- 1631
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
Q SA P P+ DS+A ++YTSGSTG PKGV++ + + N L+
Sbjct: 1632 ---GQTGNPESAANPN-----VPVKPDSLAYIIYTSGSTGRPKGVQVEHRSAVNFLYSLQ 1683
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEI-WGPLLHGRALLILSRETTRDPQKLVN------ 191
+ SDS +I + KT+ +F S+ E+ W P+ G ++ +L + +DP+ ++N
Sbjct: 1684 TRYGLSDS-DIILHKTSYSFDASIWELFWWPIA-GASVFLLPQGGEKDPEMILNALENNR 1741
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRR--LKLWVCSGETLSKELASEFFKYFGNEDGY 249
I VP++L + L Y + +P+++ LK GE L L S F+ G
Sbjct: 1742 ITAAHFVPSMLHAFLEY--INSRKQPIKKTCLKRVFAGGEQLGPHLVSRFYDLL---PGT 1796
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
+L N YG TE + Y+ L + + +PIG N +Y+L+++ GE
Sbjct: 1797 ELTNSYGPTEATVEAAYFDLPQGKE---FHNVPIGISGHNMRLYILNQKKRLLPPGCIGE 1853
Query: 310 VWVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDA 366
+++AG +A GY+ RF D+P +R+Y+TGD +G V + GR+D
Sbjct: 1854 LYIAGTGVARGYLNRPELTEERFLDDPFYPG---ERMYQTGDIARWTEEGLVEWLGRSDG 1910
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
QVK+RG+R++ E+E A+ ++ G+ + V + G + ++ + + +
Sbjct: 1911 QVKVRGYRIEPGEIEAAIRRIDGIREAAVTA-RTEHGETALYAYIEGR-----ESDDVRA 1964
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+L + L YMMP Q I++ P+ +GK+DR+ L
Sbjct: 1965 ELATRLPAYMMPAQFIKMSEWPVTPSGKLDRRAL 1998
Score = 156 bits (378), Expect = 2e-36
Identities = 131/452 (28%), Positives = 206/452 (45%), Gaps = 34/452 (7%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
S A+L KAG A+VP++P P+ RI ++++++ V+ + + VP
Sbjct: 540 SLAAAVLGILKAGGAFVPIDPGSPKERIRYVIENSGCVHVVTE--------RHQSVPA-- 589
Query: 78 FEELAQEATSHSADEPMDAETLAPL-TSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
E+ Q A D + + T+D + ++YTSG+TG PKGV L + + N L
Sbjct: 590 -EQTLQVTYIEDAGTEADGSNVQSINTADDLLYMIYTSGTTGKPKGVLLEHKNMANLLSH 648
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---- 192
Q + + ++ F E++ LL G L I+ RD +L +
Sbjct: 649 QLTNTDIDFCTNVLQY-ASVAFDVCYQELFSVLLSGGTLCIVPESIKRDVSQLFSFIDQH 707
Query: 193 -ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+V PT +L + G A R +K + +GE L+ S F+ G L
Sbjct: 708 NTEVVFFPTAFVKML-FNEEGYAQSFPRCVKHVITAGEQLT---VSRLFRQTLRLHGMHL 763
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG +E V+ Y + D + +P PIG+P+ + +Y+L + GE++
Sbjct: 764 HNHYGPSETHV-VSTYTISAGDDIPEHP--PIGKPIHHNKMYILSKNRQLQPLGIAGELY 820
Query: 312 VAGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
++GAN GYV +F +P T +YRTGD L G + Y GRTD QV
Sbjct: 821 ISGANTGRGYVNNPALTEEKFLPDPFRTDAV---MYRTGDLARLRADGQIEYIGRTDDQV 877
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG+R++ E+E LA V + VL + G E+ + + T + L
Sbjct: 878 KIRGYRIEPKEIETVLANHHAVKEAAVLIQTNESGENELCAYCSVSQA--TDPSQLRSDL 935
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P + V+SIPL NGKVD++ L
Sbjct: 936 AKELPDYMIPVKWAFVDSIPLTANGKVDQRAL 967
>UniRef50_Q0VZ70 Cluster: Non ribosomal peptide synthase; n=1;
Chondromyces crocatus|Rep: Non ribosomal peptide synthase
- Chondromyces crocatus
Length = 3912
Score = 192 bits (467), Expect = 4e-47
Identities = 158/573 (27%), Positives = 265/573 (46%), Gaps = 42/573 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA ++AG Y+P++PS P R+ +++ DA P +V+ + + P +
Sbjct: 2547 VIGMLAIFEAGGVYLPLDPSQPLERLAYLVSDARPEVVLTQQRWNDRL------PEQATR 2600
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+A + + + D++A VLYTSGSTG PKGV+++ +
Sbjct: 2601 RVALDTAWAEIEAQPEVSHQHRTAGDNLAYVLYTSGSTGTPKGVQVTVDNLSRLTPALIT 2660
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRAL-LILSRETTRDP--QKLVNIERLV 196
F + + + ++L+F S+ E+ L G AL L + E P QKL+ +
Sbjct: 2661 AFDVTPRSRVLQY-SSLSFDGSISEVAMALGAGAALHLAPAHELVPGPPLQKLLATRAIT 2719
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V TLL + L +L+ R L L + + +GE L + G + N YG
Sbjct: 2720 HV-TLLPAALRWLS----PRGLPALDVLIVTGEACPASLVRTW------ASGRRFVNAYG 2768
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE+ T + + PIG PL + IY+LD L P PG++++ GA
Sbjct: 2769 PTEITVAATAMECPVTMFQETEQPPPIGCPLQSTEIYILDAHLRPVPVGVPGDLYIGGAK 2828
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
L GY+ A R+ +P + +P RLY TGD + G + + GR D QVK+RG+
Sbjct: 2829 LTRGYIHRPALTAERYIPHPFSDRPG-ARLYVTGDIARYQLDGTIDFLGRRDNQVKVRGY 2887
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L EVE AL PGV + VV+ G+ ++ + K T+ + + L L
Sbjct: 2888 RIELGEVEAALNDHPGVREAVVVAQKDGAGDNRLVAYWAAKSTPPTTTEALRDALSKRLA 2947
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P V + ++++PL GK+DRQGL + DD +D
Sbjct: 2948 AYMIPSVFVRMDALPLNATGKIDRQGLPPV-------DDTM----LDREQFVAPRTATEE 2996
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTL 551
+ LG A G +R F++LGG+SL ++ T+++ R G+ + + A T+
Sbjct: 2997 TLTAIWSSTLGVARVG---IRDDFFKLGGHSLLALNITTQIQKRFGHVITVDSIFRAPTI 3053
Query: 552 GEVLSKMSTDPNGGADSKEATFTAVPMRDEHKK 584
VL+++ + ++ A VP+R+ K
Sbjct: 3054 A-VLARVIDEALAPTGARRALSLVVPLRERGTK 3085
Score = 153 bits (370), Expect = 2e-35
Identities = 123/385 (31%), Positives = 182/385 (47%), Gaps = 23/385 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA KAG AY+P++P++PQ R+ IL DA +++ + F + +P +
Sbjct: 547 IVALLAVLKAGGAYLPLDPTYPQQRLAFILADAGAQVILTQEK----WFDD--LPPHTAR 600
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L +A + D + T+D +A ++YTSGSTG PKGV + +
Sbjct: 601 VLDLDAIAPQLDANATSNPPLRATADHLAYIIYTSGSTGNPKGVLIPRRDTWSVARALAE 660
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL-VNIERLVLV 198
T+ + + + +L F SV EI L G AL + +E L ++R +
Sbjct: 661 TYALTPESRVLQF-ASLNFDGSVVEITMTLFSGAALHVAPQEKLLPGAPLNAFLQRHAIT 719
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L L+ L P L ++ + +GE AS G G ++ N YG T
Sbjct: 720 HVQLAPSLL-ARLPPEG--LEHVRTIMVAGE------ASSVGTVRGWLPGRRILNGYGPT 770
Query: 259 EV-MGDVTYYVLEGSDQ-LDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E +G E D L +PIGRP N +YLLD L P PGE++VA
Sbjct: 771 ETTVGAAMIAFTEADDAYLAKLDALPIGRPFYNKRVYLLDARLQPVPVGVPGEIYVASPG 830
Query: 317 LAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
LA GY+ A +F NP + P +R+YRTGD L G +++ GR D QVK+RG
Sbjct: 831 LARGYINRPAATAEKFLPNPFSETPG-ERIYRTGDLARYLPDGNLVFLGRVDNQVKLRGL 889
Query: 374 RVDLLEVERALAQVPGVDKCVVLCY 398
R++L E+E AL P V V+ +
Sbjct: 890 RIELEEIESALKSHPHVGDAAVIVH 914
>UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, terminal
component; n=5; cellular organisms|Rep: Non-ribosomal
peptide synthetase, terminal component - Pseudomonas
syringae pv. tomato
Length = 5929
Score = 191 bits (466), Expect = 5e-47
Identities = 141/453 (31%), Positives = 219/453 (48%), Gaps = 30/453 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I LL KAGAAYVP++P++P RI + L D+ P ++ S ++ S VP S +
Sbjct: 1660 IAGLLGILKAGAAYVPLDPAYPLERIAYTLGDSAPVALLSQRSVQAAL-PVSQVPVISLD 1718
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + DE + + S+A V+YTSGSTG+PKGV + + +
Sbjct: 1719 EAGLQ------DE-SERNPQVSVKPTSLAYVIYTSGSTGLPKGVMIEHRNVARLFSATED 1771
Query: 140 TFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VN 191
F +++ + VW + F SV EIWG LLHG LLI+ + +R P+
Sbjct: 1772 WFGFNEQD---VWSLFHSFAFDFSVWEIWGALLHGGRLLIVPQLVSRSPEDFYALLCSAG 1828
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ L P+ R ++ P + LR++ + GE L + ++ N +L
Sbjct: 1829 VTVLNQTPSAFRQLIAAQGENPQAHSLRQV---IFGGEALETAMLKPWYARNVNA-ATQL 1884
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE VTYY ++ D + + PIG+ + + +Y+LD P GE++
Sbjct: 1885 VNMYGITETTVHVTYYPVQPEDAQRVGAS-PIGKRIADLQLYVLDTCGEPVPLGVVGELY 1943
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
V GA +A GY+ A RF DNP + + R+YRTGD + G++ Y GR D QV
Sbjct: 1944 VGGAGVARGYLNREALTAERFLDNPFSHAAD-ARIYRTGDLARWMADGSLEYLGRNDEQV 2002
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGARTSAQHIEGK 427
KIRG R++L E+ L P V VV+ G+ ++G+ T + + +
Sbjct: 2003 KIRGFRIELGEIASRLNDHPQVLDAVVVAREDVPGDKRLVGYYTCAEDQTGLDIEQLRAW 2062
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L L YM+P + + +P+ NGK+DR+ L
Sbjct: 2063 LSGLLPDYMVPAAFVRLAGLPITANGKLDRKSL 2095
Score = 181 bits (441), Expect = 6e-44
Identities = 158/548 (28%), Positives = 250/548 (45%), Gaps = 45/548 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T++ LLA KAGA YVP++P+ P RI ++L D+ P V+ + + GVP +
Sbjct: 3783 TLVGLLAVLKAGACYVPVDPAHPGERIAYLLSDSAPVAVLAQQTFIERL-PALGVPVIAL 3841
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ +H+ P+ +A LT+ +A V+YTSGSTG PKGV + + + N + W
Sbjct: 3842 DRPHWPEQAHN---PI----VAGLTAKDLAYVIYTSGSTGQPKGVMVEHRTLENLVHWHC 3894
Query: 139 RTFP-YSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
+ F ++ S V F E+W L G L + E + + ++ +
Sbjct: 3895 QAFDLHAGSHTASV--AGFGFDAMAWEVWPALCAGATLHVPPAEIGNEQLDAL-LDWWLA 3951
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
P + + +A SR LR L TL + + + F E G+ + N YG
Sbjct: 3952 QPLQVAFLPTPVAEYAFSRQLRHPTL-----RTLL--IGGDRLRQFHREPGFAVINNYGP 4004
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE V+ S +L ++ IG+P+ N +YLLDE+ GE+++ G +
Sbjct: 4005 TEAT------VVATSGRLLPDGSLDIGKPIANTRVYLLDEQQQLVPLGVAGELYIGGEGV 4058
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF +P A QP R+YRTGD G + Y GR D QVKIRG R
Sbjct: 4059 ARGYLNQPQLTAERFLLDPFAGQPH-ARMYRTGDLARWNADGTLDYLGRNDDQVKIRGVR 4117
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILG-FVTTKPGARTSAQHIEGKLRSALT 433
++L E+E LAQ+PG+++ +V+ + ++ F+ A +A + + + L
Sbjct: 4118 IELGEIEAQLAQLPGIEEALVMAREDEPDQSRLVAYFIERADSATVAAAQLRSDMLARLP 4177
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P + +++ PL NGKVDR+ L D E
Sbjct: 4178 GYMVPSAFVRLDAWPLTANGKVDRRALPAPDREALPGRDYEPP-----QGELETALAEIW 4232
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLG 552
VG V GR F+ELGG+SL ++ I ++R RG ++ TL
Sbjct: 4233 SDLLQVGQV-GR--------HDHFFELGGHSLLAVTLIARMRRRGMDADVRVLFAQPTLA 4283
Query: 553 EVLSKMST 560
+ S + +
Sbjct: 4284 ALASAIGS 4291
Score = 180 bits (437), Expect = 2e-43
Identities = 135/446 (30%), Positives = 214/446 (47%), Gaps = 24/446 (5%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T+++LLA K+GA YVP++P+ P R+ ++L D+ P V+ + P + G+
Sbjct: 609 TLVSLLAVLKSGAGYVPIDPAHPDERVAYLLTDSAPLAVLTQPALLPRL---EGLSLPGP 665
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ L + LA LTS +A V+YTSGSTG PKGV + + + N + W
Sbjct: 666 KALLIDLERSDWPAKTGNPQLADLTSSHLAYVIYTSGSTGQPKGVMVEHRTLNNLIDWHC 725
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
F F E+W P L A L L + Q ++ +
Sbjct: 726 EAFDLRAGSHTAS-VAGFGFDAMAWEVW-PALCAGATLHLPPADIGNEQLDALLDWWLAQ 783
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
P + + +A SR LR L TL + + + F + G+ + N YG T
Sbjct: 784 PLQVAFLPTPVAEYAFSRDLRHPTL-----RTLL--IGGDRLRQFHRDPGFAVINNYGPT 836
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E V+ S +L ++ IG+P+ N ++YLLD GE+++ G ++A
Sbjct: 837 ETT------VVATSGRLLPNGSLDIGKPIANTSVYLLDSLHKLVPFGVAGELYIGGESVA 890
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +P A P+ R+YRTGD G + Y GR D QVK+RG R+
Sbjct: 891 RGYLNQPQLTAERFLRDPFAEPPQ-ARMYRTGDLARWNPDGTLEYLGRNDDQVKLRGVRI 949
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS-AQHIEGKLRSALTH 434
+L E+E +Q+PG+++ +VL + G P ++G+ T + A S + + L + L
Sbjct: 950 ELGEIESQFSQLPGIEEALVLAREDEPGQPRLVGYFTERADATPSRLEDLRTALAARLPA 1009
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P ++ ++S PL NGKVDR+ L
Sbjct: 1010 YMVPGALVRLDSWPLTANGKVDRRAL 1035
Score = 180 bits (437), Expect = 2e-43
Identities = 150/556 (26%), Positives = 250/556 (44%), Gaps = 43/556 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T+ A+LA KAGA+YVP++P+ P RI ++L+D+ P +V+ A + VP
Sbjct: 4842 TLCAMLAVLKAGASYVPVDPAHPDERIGYLLEDSAPVVVL----AQFDLLAR--VPDLHV 4895
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+A + + D + LT++++A V+YTSGSTG PKGV + + + N + W
Sbjct: 4896 PRVALDRPDWLQRD--DTPHVPGLTAENLAYVIYTSGSTGQPKGVMVEHRTLNNLVDWHC 4953
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ F + F E+W L G L + P + E+L L+
Sbjct: 4954 QAFDLRAGSQTAS-VAGFGFDAMAWEVWPALCAGAVLHL--------PPADIGNEQLDLL 5004
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ +++A P + + + + ++F + G+ + N YG T
Sbjct: 5005 LDWWLAQQLHVAFLPTPVAEYAFSRELHHPTLHTLLIGGDRLRHFKRDPGFAVVNNYGPT 5064
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E V+ S + + IG+P+ + +Y+LD P PGE+++ G +A
Sbjct: 5065 ETT------VVASSGLMLPQGVLHIGKPVAHARLYVLDAHSQPVPLGVPGELYIGGTGVA 5118
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF D+P + R+YRTGD L G + Y GR D QVKIRG RV
Sbjct: 5119 RGYLNRPDLTAERFLDDPFSNVTA-ARMYRTGDLVRWLADGTLEYLGRNDDQVKIRGVRV 5177
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E+ LAQ PGV + VV L+ G ++ + T + A SA + +L L Y
Sbjct: 5178 ELGEIEQQLAQCPGVAEAVVTTQRLEDGTLRLVAYFTRRDAALDSAT-LRSQLLGRLPEY 5236
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P + ++++PL NGKVDR+ L A D+D
Sbjct: 5237 MVPATYVGLDALPLTQNGKVDRKAL--------------PAPDMDALATAIYQAPSSVLE 5282
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEV 554
G + F+ELGG+SL++I ++ L+ G + +++ ++ +
Sbjct: 5283 ERLAQLWAEVLEVGRIGRHDSFFELGGHSLSAIRLVSLLQKAGLPLTLAELFQHPSITAL 5342
Query: 555 LSKMSTDPNGGADSKE 570
+ P D++E
Sbjct: 5343 AGLLDQRPLPTTDAQE 5358
Score = 163 bits (396), Expect = 2e-38
Identities = 131/446 (29%), Positives = 209/446 (46%), Gaps = 25/446 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++ LA K A YVP++ + P R ++L D + V+ +M + V +
Sbjct: 2734 LISQLAIGKCAATYVPLDVNAPAERQQYMLGDCQAKCVL----TQSAMSIATSVQRIDLD 2789
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L + D+P L P +D+ A V+YTSGSTG PKGVR+ + I RL
Sbjct: 2790 QLNLD------DQPAHDPGL-PQGADTAAYVMYTSGSTGAPKGVRVGHRGIV-RLVLNNG 2841
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+++ + I + + F S E+WG LL+G L+++ T DP + R V
Sbjct: 2842 YAEFNEQDSIA-FASNPAFDASTMEVWGALLNGGQLVVIEHTTLIDPARFSAALRHGNVS 2900
Query: 200 TL-LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L L + L + L L++ + GE F G L N YG T
Sbjct: 2901 VLFLTTALFNQYVQMIPEALGGLRVLISGGERADPV---SFRAMLAQAPGLHLLNGYGPT 2957
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T Y + ++PIGRP+ N +Y+L+ + GE+++ G +A
Sbjct: 2958 ETTTFATAYDVRAL--ASSAESVPIGRPIGNTRVYVLNAQQRLAPLGVIGELYIGGDGVA 3015
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ +F +P + QP +YRTGD G L G + GR D QVKIRG R+
Sbjct: 3016 LGYLNRPELTVEKFIADPFSDQPGAM-MYRTGDLGRWLEDGQLECLGRNDDQVKIRGFRI 3074
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ-HIEGKLRSALTH 434
+L E+ L Q+PG+ + VVL + GN ++ + T++ A + +++ L
Sbjct: 3075 ELGEIVNCLHQLPGIREAVVLAREDEPGNVRLVAYFTSQQDVEAPAPGQMRAHMQANLPD 3134
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P IE+ ++PL NGK+D + L
Sbjct: 3135 YMVPVAFIELTALPLTANGKLDSRAL 3160
>UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1;
Streptomyces anulatus|Rep: Actinomycin synthetase III -
Streptomyces chrysomallus
Length = 4247
Score = 191 bits (466), Expect = 5e-47
Identities = 138/449 (30%), Positives = 217/449 (48%), Gaps = 23/449 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA KAGAAY+P++P +P R+ H++ DA+P+LV+ + +
Sbjct: 522 VVAVLAVLKAGAAYLPLDPEYPANRLAHMVTDAQPTLVLTTTETEAKLPDRHPGLLLDDP 581
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + A +P + L D A V+YTSGSTG+PKGV + + N L W R
Sbjct: 582 AVLADLSGRPAHDP-----VVELHPDHPAYVIYTSGSTGVPKGVVMPAGGLLNLLQWHHR 636
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLV- 196
+ TA++F S E+ + G+ L+I E RD + +R V
Sbjct: 637 AVGDEPGTRTAQF-TAISFDVSAQEVLSSVAFGKTLVIPDEEVRRDAARFAGWLDDRQVD 695
Query: 197 --LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
P L+ L A+ R L +L+ +GE L+ L+ + + G +L N
Sbjct: 696 ELFAPNLVLEALAEAAV-ETGRTLPQLRTVAQAGEALT--LSRTVRAFHRSAPGRRLHNH 752
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE VT + L G D D PIGRP+DN Y+ + GE+++AG
Sbjct: 753 YGPTET-HVVTAHAL-GDDPEDWRLPAPIGRPIDNTHAYVRTRAVRLVEPGVVGELYIAG 810
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIR 371
A LA GY+G A RF +P+ +P R+YRTGD G + + GR D QVK+R
Sbjct: 811 AGLARGYLGRPALTAERFVADPYGLEPG-GRMYRTGDLVRRNPDGELEFCGRADHQVKVR 869
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++ E+E+ L P + + V+ G+ ++ +V + R + + R
Sbjct: 870 GFRIEPGEIEKVLTDHPDIAQAAVVTRPHRPGDTRLVAYVVGREALR--PEQVREFTRER 927
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +M+P V+++E +PL NGK+DR L
Sbjct: 928 LPEHMVPAAVVQLERLPLTPNGKLDRAAL 956
Score = 180 bits (439), Expect = 1e-43
Identities = 128/410 (31%), Positives = 201/410 (49%), Gaps = 17/410 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA K GAAY+P++P P R++H+L DA P+L++ D + + ++ + +
Sbjct: 1584 VVALLAVLKTGAAYLPLDPDHPAARLSHVLGDARPALLLTDTRTEQHLPADADTRRLALD 1643
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + AE S A V+YTSGSTG PKGV + +SA+ N + R
Sbjct: 1644 SAEVRALLADCPDTDPAEEGVTPAPGSAAYVIYTSGSTGRPKGVVVPHSALVNFVTAMRR 1703
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P E + T + F + E++ PLL G A+++ +E P ++++ V
Sbjct: 1704 QAPLRPQERLLA-VTTVAFDIAALELYHPLLSGAAVVLAPKEAVPQPSAVLDLIARHGVT 1762
Query: 200 TLLRS-ILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
T+ + L L +G + LR L++ V GE L LA E + ++ L N YG T
Sbjct: 1763 TVQGTPSLWQLLVGHDAEALRGLRMLV-GGEALPLSLA-EALRALTDD----LVNLYGPT 1816
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T L G PIGRP+ N +Y+LD+ L P GE+++AGA LA
Sbjct: 1817 ETTIWSTAAELAGGT-----GAAPIGRPIANTRVYVLDDGLQPVAPGVVGELYIAGAGLA 1871
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +P+ +P R+YRTGD G + + GR D QVK+RG R+
Sbjct: 1872 RGYLDRPALTAERFPADPYGLEPG-GRMYRTGDLVRWNPDGELEFVGRADHQVKVRGFRI 1930
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
+ E+E+ L P + + V+ G+ ++ +V T A + +E
Sbjct: 1931 EPGEIEKVLTDHPDIAQAAVVVREDQPGDARLVAYVVTGGSADARDEQVE 1980
Score = 133 bits (321), Expect = 2e-29
Identities = 121/417 (29%), Positives = 183/417 (43%), Gaps = 31/417 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T+ +LA K GA Y+P++ +P R +L + L+I D + D +
Sbjct: 3059 TVTTVLALAKTGATYIPLDSRYPADRYRLVLDETRTKLLITDHTTDLD---------TTT 3109
Query: 79 EELAQEATSHSADEPMDAE-TLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ T H ++P + T P D A ++YTSGSTG PKGV ++ I L
Sbjct: 3110 TQFNPADTPHDGEDPGNPNHTTHP---DDAAYIMYTSGSTGRPKGVIATHRNI-TALALD 3165
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
R P + + TA F S EIW PLL+G + +L+ D +
Sbjct: 3166 PRFDPTAHRRVLLHSPTA--FDASTYEIWVPLLNGNTV-VLAPTGDLDVHTYHRVITDQQ 3222
Query: 198 VPTL-LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ L L S + L + R++ GE +S + + + + + YG
Sbjct: 3223 ITALWLTSWVFNLLTEQSPETFTRVRQIWTGGEAVSGATVTRLQQACPDTT---VVDGYG 3279
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T++ + +PIGRP+ Y+LD+ L P GE+++AG+
Sbjct: 3280 PTETTTFATHHPVP--TPYTGSAVVPIGRPMATMHTYVLDDSLQPVAPGVTGELYLAGSG 3337
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGH 373
LA GY+ A RF NP+A E R+YRTGD L YAGR D QVK+RG
Sbjct: 3338 LARGYLDRPALTAERFVANPYAAPGE--RMYRTGDLARWNPDDHLEYAGRADHQVKVRGF 3395
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFV---TTKPGARTSAQHIEGK 427
R++ E+E L P V + V GNP ++ +V T+ P + QH G+
Sbjct: 3396 RIEPGEIENVLTDHPAVAQAAVHLNRDQPGNPRLVAYVVADTSAPSSDVDQQHQIGE 3452
>UniRef50_Q70C52 Cluster: Non-ribosomal peptide synthase; n=1;
Xanthomonas albilineans|Rep: Non-ribosomal peptide
synthase - Xanthomonas albilineans
Length = 1959
Score = 191 bits (466), Expect = 5e-47
Identities = 159/533 (29%), Positives = 254/533 (47%), Gaps = 43/533 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL KAG YVP++P +P I IL DA+P L++ D + + VP +
Sbjct: 95 LIALLGVLKAGGCYVPLDPHYPTTYIQQILDDAQPRLLLCGKDIDGQLIQ---VPRLRLD 151
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A H+ P+ L P +A V+YTSGSTG PKGV + + I N L +
Sbjct: 152 DAAIARQPHT---PLP-HALHPA---QLAYVMYTSGSTGRPKGVMVPHRQILNWLHALWA 204
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
P+ E + KT++ F SV E+ LL G + + +T RD V I
Sbjct: 205 RAPFEAGERVAQ-KTSIAFAISVKELLAGLLAGVPQVFIDEDTVRDIPAFVRALETWQIT 263
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
RL P+ L ++L ++A P + L RL+ S E EL + +
Sbjct: 264 RLYTFPSQLNALLDHVAETP--QRLARLRQLFVSIEPCPAELLQRLRTLLPACTAWYI-- 319
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE+ D+TY + ++Q +P+GRP+ N +++LDE+L P GEV +
Sbjct: 320 -YGCTEI-NDMTY--CDPAEQHSGSGFVPVGRPIANTKVHVLDEQLRPLPPGIMGEVHIE 375
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKI 370
+ GY GG A RF NP+ P RLYRTGD L+ G + GR D +VK+
Sbjct: 376 SLGITHGYWRQGGLTAARFIANPYG--PPGSRLYRTGDMARLLDNGTLELLGRRDYEVKV 433
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG+RVD+ +VE+ALA V + V+ + PE+L +V + G + + L+
Sbjct: 434 RGYRVDVRQVEKALAAHLQVAEAAVIGWPQGSPTPELLAYVVPRQGV-LNLDELRKLLQE 492
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P + + ++P L NGK+D L + ++++D +++ +
Sbjct: 493 RLPTYMLPTRFQSLPALPRLPNGKLDTLSLPEPQAASSDSDYLAPRSEVEITLAKLWSEL 552
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
+AA +SL F+ LGG+SL + +++R + + +E+
Sbjct: 553 LTP----------AQAAPLRVSLNDNFFNLGGHSLLATQLFSRIR-QSFDIEV 594
Score = 191 bits (466), Expect = 5e-47
Identities = 159/533 (29%), Positives = 254/533 (47%), Gaps = 43/533 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL KAG YVP++P +P I IL DA+P L++ D + + VP +
Sbjct: 1146 LIALLGVLKAGGCYVPLDPHYPTTYIQQILDDAQPRLLLCGKDIDGQLIQ---VPRLRLD 1202
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A H+ P+ L P +A V+YTSGSTG PKGV + + I N L +
Sbjct: 1203 DAAIARQPHT---PLP-HALHPA---QLAYVMYTSGSTGRPKGVMVPHRQILNWLHALWA 1255
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
P+ E + KT++ F SV E+ LL G + + +T RD V I
Sbjct: 1256 RAPFEAGERVAQ-KTSIAFAISVKELLAGLLAGVPQVFIDEDTVRDIPAFVRALETWQIT 1314
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
RL P+ L ++L ++A P + L RL+ S E EL + +
Sbjct: 1315 RLYTFPSQLNALLDHVAETP--QRLARLRQLFVSIEPCPAELLQRLRTLLPACTAWYI-- 1370
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE+ D+TY + ++Q +P+GRP+ N +++LDE+L P GEV +
Sbjct: 1371 -YGCTEI-NDMTY--CDPAEQHSGSGFVPVGRPIANTKVHVLDEQLRPLPPGIMGEVHIE 1426
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKI 370
+ GY GG A RF NP+ P RLYRTGD L+ G + GR D +VK+
Sbjct: 1427 SLGITHGYWRQGGLTAARFIANPYG--PPGSRLYRTGDMARLLDNGTLELLGRRDYEVKV 1484
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG+RVD+ +VE+ALA V + V+ + PE+L +V + G + + L+
Sbjct: 1485 RGYRVDVRQVEKALAAHLQVAEAAVIGWPQGSPTPELLAYVVPRQGV-LNLDELRKLLQE 1543
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P + + ++P L NGK+D L + ++++D +++ +
Sbjct: 1544 RLPTYMLPTRFQSLPALPRLPNGKLDTLSLPEPQAASSDSDYLAPRSEVEITLAKLWSEL 1603
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
+AA +SL F+ LGG+SL + +++R + + +E+
Sbjct: 1604 LTP----------AQAAPLRVSLNDNFFNLGGHSLLATQLFSRIR-QSFDIEV 1645
>UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep:
MassC - Pseudomonas fluorescens
Length = 3774
Score = 191 bits (466), Expect = 5e-47
Identities = 165/547 (30%), Positives = 259/547 (47%), Gaps = 56/547 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ L A KAGAAYVP++P++P RIT++L D+ P++V+ S + E VP + +
Sbjct: 1665 VIGLYAILKAGAAYVPLDPAYPLERITYMLHDSAPTVVLAQAST-LGLLGE--VPVVNLD 1721
Query: 80 ELA-QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
Q +H+ P + A V+YTSGSTG PKGV + + NRL W
Sbjct: 1722 SPTWQHQPTHN-----------PQAASVAAYVIYTSGSTGQPKGVINEHPGVVNRLLWMQ 1770
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ + S+ + + KT +F SV E + PL G L++ +DP L + V
Sbjct: 1771 DEYGLTASDAV-LQKTPFSFDVSVWEFFWPLFTGARLVMARAGGHKDPDYLCQVIEAERV 1829
Query: 199 PTL--LRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
TL + S+L ++LA G S+ +++ +CSGE L L F + E G L N Y
Sbjct: 1830 TTLHFVPSMLDVFLAHGDVSQAAGLVRV-MCSGEALPGSLVRRFKQQLP-EVG--LYNLY 1885
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE DVT + G+ D PIG+P+ N +Y+LD +L P GE+++AG
Sbjct: 1886 GPTEAAVDVTAWDCAGALVPD---NTPIGKPIANTRLYVLDGQLQPVPLGVVGELFIAGV 1942
Query: 316 NLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
+A GY+ A RF D+P R+YRTGD L G + Y GR D QVKIRG
Sbjct: 1943 QVARGYLNRPELTAERFLDDPFTP----GRMYRTGDVSRYLPDGTLEYLGRNDDQVKIRG 1998
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E++ L + P V + V+ ++ + T G + + + L L
Sbjct: 1999 LRIELGEIQARLTEHPAVQEAAVIA-----REQRLIAYYT---GVPSEVESLRAHLLQHL 2050
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
+M+P + ++ +PL NGK+DR+ L + + D E V
Sbjct: 2051 PEFMLPASFVHLQVLPLSPNGKLDRKALPAPGLDALSVRDYEAPV------------GDT 2098
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
+ A L R + F+ELGG+SL ++ + ++R G ++ G TL
Sbjct: 2099 EITLAALWAELLNVER--VGRHDNFFELGGHSLLAVSLMGRMRRLGLSADVKVLFGQPTL 2156
Query: 552 GEVLSKM 558
+ + +
Sbjct: 2157 SALAAAL 2163
Score = 158 bits (383), Expect = 6e-37
Identities = 148/541 (27%), Positives = 249/541 (46%), Gaps = 45/541 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++ LA K AAYVP++ + P R +L+D+ + ++ +D S+ ES V +
Sbjct: 2696 LISQLAILKCAAAYVPLDINAPAERQAFMLQDSGAAWLL--TGSDCSV--ESAVQRLDLD 2751
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA + S+ P P S S+A ++YTSGSTG+PKGV + + I RL
Sbjct: 2752 TLALD--SYPEHNPG-----LPQPSHSVAYIMYTSGSTGMPKGVLVPHRGI-TRLVLNNG 2803
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
++ + + + + F S ++WG LL+G + ++ T DP + V V
Sbjct: 2804 YADFNPDDRVA-FASNPAFDASTMDVWGALLNGGQVQVIDHATLLDPLAFGAALQGVTVL 2862
Query: 200 TLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ ++ Y+ L P + L L++ +C GE + F G +L + YG T
Sbjct: 2863 FVTTALFNQYVQLIPQA--LAGLRILLCGGERADP---AAFRNLLALAPGLRLVHCYGPT 2917
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T + + + D ++P+GRP+ N IY+LD +L GE+ + G +A
Sbjct: 2918 ETTTYATTHEVR-TIAADA-DSVPVGRPISNTQIYVLDAQLHLLPLGVSGEICIGGDGVA 2975
Query: 319 AGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A +F NP P LYRTGD G G + GR D QVKIRG R+
Sbjct: 2976 QGYLNRPELTAEKFVQNPF--NPG-ALLYRTGDLGRWSADGLLECIGRNDDQVKIRGFRI 3032
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E +A G+ + VVL G+ ++ + T G + + L++ L Y
Sbjct: 3033 ELGEIEARMATFAGIREGVVLAREDVPGDKRLVAYFTW-AGEPVGIESVRAYLQAHLPAY 3091
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P + +E +PL NGKVDR+ L + + + E VD
Sbjct: 3092 MVPSAFVALEHLPLTANGKVDRKALPLPTWDASASGTFEAPVD---------------AL 3136
Query: 495 XXTVGAVLGRAAR-GTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
T+ + + + F+ELGG+SL ++ + +L + G V +++ +++
Sbjct: 3137 EQTLAQLWAEVLKLEPVGRHDSFFELGGHSLLAMRLVNRLDEAGLPVSLAELFEHASVAS 3196
Query: 554 V 554
V
Sbjct: 3197 V 3197
Score = 149 bits (360), Expect = 4e-34
Identities = 134/449 (29%), Positives = 202/449 (44%), Gaps = 43/449 (9%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
T+ LLA KAGA YVP++PS P R+ ++L D+ P V+ A VP +
Sbjct: 625 TLAGLLAILKAGAGYVPVDPSHPAERLHYLLSDSAPVAVL-TQHALLERLPALDVPVINL 683
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + HSA P T+A + ++A V+YTSGSTG+PKGV + + + N + W
Sbjct: 684 DRFTWQ--HHSASNP----TIA-VGPTNLAYVIYTSGSTGLPKGVMVEHHTVANLVDWHC 736
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRAL-LILSRETTRDPQKLVN--IERL 195
F F E+W L G L L + E D L+ +
Sbjct: 737 SAFDLRAGRHTAS-VAGFGFDAMAWEVWPALCVGATLHLPPAHEGGEDIDALLAWWCAQP 795
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ V L + Y P R L G+ L + FG ++L N Y
Sbjct: 796 LDVSFLPTPVAEYAFSQNIEHPTLRTLL--VGGDRL---------RQFGRAQRFELINNY 844
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE V+ S +++ + IG+P+ N +Y+LD P GE++V G
Sbjct: 845 GPTEAT------VVATSGKVEAGQPLHIGKPIANAKVYVLDPHQRPVPLGVAGELYVGGK 898
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
+A GY+ A RF +P R+YRTGD L G + Y GR D QVKIRG
Sbjct: 899 GVARGYLNRPELTAERFVRDPFNAG----RMYRTGDLVRWLPDGTLDYLGRNDDQVKIRG 954
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLRSA 431
R++L E+E L Q+PG+ + V + ++ + T P + I L +
Sbjct: 955 VRIELGEIETQLNQLPGILEAVAVV-----REERLVAYFTENPQLDPLTLAEIRAHLVAH 1009
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P ++++++PL NGK+DR+ L
Sbjct: 1010 LPDYMVPVAFMKLDALPLTANGKLDRKAL 1038
>UniRef50_A0UVJ0 Cluster: Amino acid adenylation domain; n=2;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 1499
Score = 191 bits (466), Expect = 5e-47
Identities = 147/542 (27%), Positives = 262/542 (48%), Gaps = 39/542 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AY+P++ ++P RI I+KD+ S+++ D++ + E
Sbjct: 521 VIGILAIIKAGGAYLPIDSTYPAERIEFIVKDSGTSILLTDNTIPKETNYNGHIINLKDE 580
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + + E + T + V+YTSGSTG PKGV + + + N +WW +
Sbjct: 581 NLYK-------GQVCNLEKINKTTD--LVYVIYTSGSTGAPKGVMVEHRGLVNYIWWAKK 631
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ ++ E ++ T+L+F +V I+ PL+ G +++ + T L+ I R V
Sbjct: 632 MYVRNEKEVFPLY-TSLSFDLTVTSIFTPLISGNTIVVYYDDGTEFI--LLRILRENKVS 688
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + + + + +K ++ GE L LA +K FG + ++ N YG TE
Sbjct: 689 IIKLTPVHLSIIKDMNNDNSSVKRFIVGGEDLKVALAHSIYKSFGGD--IEIFNEYGPTE 746
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ + + + DL ++PIG P DN IY+LD+ L+P GE++V+GA +
Sbjct: 747 TVVGCMIHKYDVKN--DLGVSVPIGIPADNIQIYILDKNLNPVPVETIGELYVSGAGVTR 804
Query: 320 GYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ RF DNP + ++Y+TGD L G ++Y GR+D QVK+RG+R++
Sbjct: 805 GYLNREELTKERFVDNPFI---KGSKMYKTGDLAKHLHGGEIVYMGRSDYQVKLRGYRIE 861
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L E+E L + +V+ ++GN + ++ + S I L S L YM
Sbjct: 862 LGEIENYLFSHNSITDAIVIDRNDEKGNKYLCAYIVSTTDLDIS--EIRMFLSSKLPDYM 919
Query: 437 MP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXX 495
+P + ++S+PL NGKVDR K+ ++++ C
Sbjct: 920 LPSHFVILQSLPLTSNGKVDR----KLLPEPKLEEESKAYY---CE----FENDTEEKII 968
Query: 496 XTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEVL 555
+ VLG +S FY+LGG+S+ +I ++L+ +++ D L + +GE +
Sbjct: 969 KVICEVLG---IDKISPTDNFYQLGGDSIKAIQIASRLKSEAINLKVKDILLNTIIGEFV 1025
Query: 556 SK 557
+
Sbjct: 1026 ER 1027
>UniRef50_Q0RMQ5 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Frankia alni ACN14a|Rep: Putative non-ribosomal
peptide synthetase - Frankia alni (strain ACN14a)
Length = 2623
Score = 191 bits (465), Expect = 7e-47
Identities = 153/450 (34%), Positives = 218/450 (48%), Gaps = 47/450 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ A KAGAAYVP+E P R+ +L A P +V+ + P + SG P + E
Sbjct: 2109 VVAVYAVVKAGAAYVPVEVDAPVDRVRQVLAGAAPVVVL--EGVLPDV---SGYPVVAPE 2163
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L D A V+YTSGSTG PKGV +S+ +I NRL W
Sbjct: 2164 RR--------------------LLPDHAAYVIYTSGSTGGPKGVVVSHRSIMNRLAWGVE 2203
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL--VL 197
F + + + T+ +F SV E + PL G A+++ + RDP LV++ R V
Sbjct: 2204 YFGVGPDDRVLL-STSASFDVSVPEFFAPLQVGAAVVVARPDGRRDPGYLVDLVRREGVT 2262
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
+ S+L PA+R L+ +GE LA+ + G + N YG
Sbjct: 2263 GADFVPSLLEAFVAEPAARECVSLRWVEVAGEAFGAGLANRVVEVL---PGCGVFNLYGP 2319
Query: 258 TEVMGDVTYYV-LEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE +VT + + G+D+ +PIG P+ N +Y+LD L P PGE+++AG
Sbjct: 2320 TEAAVEVTSWRHVVGADR------VPIGVPIWNMRVYVLDAGLRPVPPGVPGELYLAGVG 2373
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGH 373
LA GY+G G A RF P E R+YRTGD G V Y GR+D QVK+RG
Sbjct: 2374 LARGYLGQVGLTAGRFVACPFGGVGE--RMYRTGDVVRWNSAGQVEYLGRSDFQVKVRGF 2431
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE---GKLRS 430
R++L E+E+AL PG+ V + GN ++ +V + A IE +LR
Sbjct: 2432 RIELGEIEQALTSQPGIGGAVAIVREDQAGNQRLVAYVVAEDQASVGQPDIEEVTDRLRR 2491
Query: 431 ALTHYMMPQVI-EVESIPLLVNGKVDRQGL 459
L YM+P VI + P +GKVDR L
Sbjct: 2492 QLPEYMVPSVIVPLTEFPTTPSGKVDRAAL 2521
Score = 132 bits (320), Expect = 3e-29
Identities = 126/461 (27%), Positives = 204/461 (44%), Gaps = 37/461 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL K+GA Y+P++P + GR+ +L DA + D A + + + +
Sbjct: 558 VVGLLGILKSGAGYLPLDPKYLTGRVDVVLSDAAARFAV-TDVATWQALPPNDLSVLTLD 616
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ ++ D A + PL D++A V+YTSGSTG PK V +++ ++ N + R
Sbjct: 617 D--RDGWDSRGDGADGAGRVPPLGPDNLAYVMYTSGSTGRPKAVAITHRSVVNGVRELAR 674
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
S + T++ F SV E+ L G ++ ++ + + + VP
Sbjct: 675 VLSPSAGWRMLAG-TSVNFDVSVFELLTALSTGGTAEVVPSALVLGEREGWHGQVISAVP 733
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
++L ++ +L P++ +R + V +G+ L L + + + ++ N YG +E
Sbjct: 734 SVLGELVDHL---PSTSGVRSV---VLAGDLLPTRLVRQVREALPDA---RIVNCYGQSE 784
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
T+ L S+ PIG PL N Y+L L+P GE++VAG L
Sbjct: 785 SFYATTFS-LAASEPSPQAEVAPIGTPLGNMRAYVLGPGLAPVPPGVVGELYVAGRCLGR 843
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRVD 376
GY G G A RF NP E R+YRTGD G + GR D QVK+RG R++
Sbjct: 844 GYHGQPGLTAVRFVANPWCHPGE--RMYRTGDLARRDADGRLECVGRGDGQVKVRGFRIE 901
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT-TKPGA----------------RT 419
EVE G+ + VV+ G ++ +V T GA
Sbjct: 902 TAEVEAVCELHLGISRAVVVGREAPSGGRRLVAYVVHTGEGAVGDDGAGGIGDVDMQSGA 961
Query: 420 SAQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
SA + L + L YM+P + V +P GK+DR L
Sbjct: 962 SAAELRRFLAARLPDYMVPSAFVVVGELPYGPTGKLDRSAL 1002
>UniRef50_P39845 Cluster: Peptide synthetase 1; n=8; Bacillus|Rep:
Peptide synthetase 1 - Bacillus subtilis
Length = 2561
Score = 191 bits (465), Expect = 7e-47
Identities = 145/450 (32%), Positives = 225/450 (50%), Gaps = 34/450 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA KAG AY+P++P++P+ R++++LKD+ SL++ P P S E
Sbjct: 522 LIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLL----TQPG----CSAPNFSGE 573
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + TS A E + P S+A V+YTSGSTG PKGV + + + L
Sbjct: 574 TLEVDMTS-LASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQH 632
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
FP S+ ++I + KT+ +F SV +++ L G + +L +D +V N+
Sbjct: 633 QFPLSE-DDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAIHQENVT 691
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+P +L S L + S LK GE L+ A+ F L +
Sbjct: 692 TAHFIPAMLNSFLDQAEIERLS-DRTSLKRVFAGGEPLAPRTAARFASVLPQ---VSLIH 747
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D +YVL+ D IPIG+P+ +Y+LD L+ GE+++A
Sbjct: 748 GYGPTEATVDAAFYVLDPERDRDRL-RIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIA 806
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA +A GY+ RF ++P +R+Y+TGD L G V + GRTD QVKI
Sbjct: 807 GAGVARGYLNRPALTEERFLEDPFYPG---ERMYKTGDVARWLPDGNVEFLGRTDDQVKI 863
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG+R++ E+E AL + GV + V D G PE+ +V G + + + +L+
Sbjct: 864 RGYRIEPGEIEAALRSIEGVREAAV-TVRTDSGEPELCAYV---EGLQRN--EVRAQLQR 917
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P +IE+E P+ +GK+DR L
Sbjct: 918 LLPGYMVPAYMIEMEQWPVTPSGKLDRNAL 947
Score = 140 bits (340), Expect = 1e-31
Identities = 141/575 (24%), Positives = 246/575 (42%), Gaps = 49/575 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +LA KAG Y+P++ +P+ RI +IL+D+ +++ + S P +
Sbjct: 1561 IVGVLAVMKAGGVYIPIDAHYPKARIEYILRDSGADILLLQRELKHLI---SNSPESEMS 1617
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN-RLWWQF 138
+ + S +E L+P + + I+ YTSG+TG PKGV ++Y + L W
Sbjct: 1618 HIFLD-DEGSFEESNCNLNLSPAPEEPVYII-YTSGTTGAPKGVIVTYQNFTHAALAW-- 1673
Query: 139 RTFPYSDSEEICVWKTALTFVDSVC-EIWGPLLHGRALLILSRETTRDP---QKLVNIER 194
R D + + + + A D ++ L +G L++ ET +P K++ +R
Sbjct: 1674 RQIYELDRKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIYKIIKSQR 1733
Query: 195 LVLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ ++ P L+ ++ Y+ P L + + + + + FG ++
Sbjct: 1734 ITVMESTPALIIPVMEYVYRNQFKLP--DLDILILGSDMVKAQDFKTLTDRFG--QSMRI 1789
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE D ++Y + +PIG PL N +Y+L + GE+
Sbjct: 1790 INSYGVTEATIDSSFYETSMGGEC-TGDNVPIGSPLPNVHMYVLSQTDQIQPIGVAGELC 1848
Query: 312 VAGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
+ GA +A GY +F +NP + +RLYRTGD L G + GR D QV
Sbjct: 1849 IGGAGVAKGYHHKPDLTQMKFTENPFVSG---ERLYRTGDRACWLPNGTIRLLGRMDYQV 1905
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KI G+R++ E+E L Q V + V G + ++ T+A + L
Sbjct: 1906 KINGYRIETEEIESVLLQTGLVREAAVAVQHDKNGQAGLAAYIVPS-DVNTNA--LRAAL 1962
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
L YM+P +I + ++PL +NGK+DR L NN ++
Sbjct: 1963 TKELPAYMIPAYLIPLVNMPLTLNGKLDRNAL----PAPNNVLSRPYTAPVNDLQKTMAY 2018
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
VG + F+ELGG+S+ ++ +L G+ + I D
Sbjct: 2019 IWEDVLSMSRVG------------IHDSFFELGGDSIKALQVAARLAAEGWSMTIRDLFR 2066
Query: 548 ASTLGEV---LSKMSTDPNGGADSKEATFTAVPMR 579
ST+ E+ ++ +++ + G EA T + R
Sbjct: 2067 YSTIQELCGHITPLASQADQGPAEGEAELTPIQRR 2101
>UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 11/17 - Photorhabdus luminescens subsp.
laumondii
Length = 5457
Score = 190 bits (464), Expect = 9e-47
Identities = 157/548 (28%), Positives = 249/548 (45%), Gaps = 35/548 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA K GA YVP++PS P R ++ D L++ D AD + VP
Sbjct: 1423 VVAQLAILKVGAVYVPVDPSMPDERKNWLISDCSARLLLTDTQAD--IPANLTVPLLRLS 1480
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ Q T +E + + P +S +A ++YTSGSTG PKGV + + A+ RL
Sbjct: 1481 D--QSDTDGREEECFNPD--LPRSSAELAYIMYTSGSTGTPKGVLVPHRAVV-RLVIN-N 1534
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ ++ + F S E+W PLL G AL+++ R T PQ+LV + + +
Sbjct: 1535 DYAEVGPDDRVAFTANPAFDASTFEVWAPLLSGGALVVIDRATLLTPQELVLVLQAHHIT 1594
Query: 200 TLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L +I ++ L P P L ++K+ + G+ ++ ++ N +L YG +
Sbjct: 1595 VLWLTIGLFNRLAPELSPVLPQIKILIFGGDIPDLQVIAQ---VLNNRPPQQLLQAYGPS 1651
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T Y + Q IPIGRP+ N IYLL+ P GE++V G +A
Sbjct: 1652 EGTTFTTMYPIVALTQ--GVTRIPIGRPIANTRIYLLNAYGQPVPLGVTGEIYVGGDGVA 1709
Query: 319 AGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY+ A RF +P + QP+ R+YRTGD L G + + GR D QVKIRG R+
Sbjct: 1710 CGYLNRPDQTAERFLTDPFSDQPD-ARMYRTGDLARYLPDGNLEFLGRNDQQVKIRGFRI 1768
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+ E+E L + P V + VL G D + ++ +V + A + L + L Y
Sbjct: 1769 EPGEIEARLVEHPAVREAAVLALG-DGSDKRLVAYVAAE-AHEGLAMTLRDHLSAILPDY 1826
Query: 436 MMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P + +E+ PL NGK+DR+ L D+ A + +
Sbjct: 1827 MVPSAFVRLEAFPLTPNGKLDRRAL-------PAPDEEAFARQVYVAPQGEMEIALATIW 1879
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEV 554
+G +S F+ LGG+SL ++ + LR G + + D + L E+
Sbjct: 1880 RELLGI-------EQVSRYDSFFALGGHSLLAVRMVEHLRHLGLTLAVRDLFQSPVLLEL 1932
Query: 555 LSKMSTDP 562
+ P
Sbjct: 1933 AQTLGQHP 1940
Score = 180 bits (439), Expect = 1e-43
Identities = 139/446 (31%), Positives = 213/446 (47%), Gaps = 24/446 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA KAGA YVP++PS P R ++ D L++ D AD +P
Sbjct: 3576 VVAQLAILKAGAVYVPVDPSMPDERKHWLISDCSARLLLTDTRAD--------IPANLTI 3627
Query: 80 ELAQEATSHSADEPMD-AETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L + + SA+ D P +S +A ++YTSGSTG PKGV + + A+ RL
Sbjct: 3628 PLLRLSDKKSANREQDHVNPNLPRSSAELAYIMYTSGSTGTPKGVLVQHRAMV-RLVIN- 3685
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ E+ + F S E+W PLL+G AL+++ R T PQ+LV + +
Sbjct: 3686 NGYANIGPEDRVAFTANPAFDASTFEVWAPLLNGGALVVIDRATLLTPQELVLTLQEHRI 3745
Query: 199 PTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
L +I ++ L P L ++K+ + G+ ++ ++ N +L YG
Sbjct: 3746 TVLWLTIGLFNRLAAELSPILPQIKILIFGGDIPDLKVIAQVLD---NRPPQQLLQAYGP 3802
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
+E T Y +E Q IPIGRP+ N +YLLD P GE++V G +
Sbjct: 3803 SEGTTFTTMYPIEALPQG--VSRIPIGRPIANTRVYLLDVYGQPVPPGVIGEIYVGGDGV 3860
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF +P + P+ R+YRTGD L G + + GR D QVKIRG R
Sbjct: 3861 AQGYLNRPELTAERFLVDPFSDDPD-ARMYRTGDLARYLPDGNLEFMGRNDQQVKIRGFR 3919
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++ E+E L + P V + VL G D + ++ +V + L L
Sbjct: 3920 IEPGEIEARLVEHPAVREAAVLALG-DGPDKRLVAYVVALADDGL-VNSLRAYLSKILPD 3977
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + +++ PL NGK+DR+ L
Sbjct: 3978 YMVPSAFVRLDAFPLTPNGKLDRRAL 4003
Score = 179 bits (435), Expect = 3e-43
Identities = 139/447 (31%), Positives = 209/447 (46%), Gaps = 24/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG AYVP++P++P R+T+IL D PS+V+ D + ++ E+ V +
Sbjct: 2499 VVALLAVLKAGGAYVPLDPTYPGERLTYILNDTAPSVVLADATGQAALGDEALVGLTVLD 2558
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
Q D P + LT +A V+YTSGSTG PKGV + + A+ R
Sbjct: 2559 PNIQ------PDLPDSNPQVPALTPQHLAYVIYTSGSTGQPKGVMVEHQAVYQRYLGVNE 2612
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ ++ + + + A F SV E + L +G AL+I + + + R +
Sbjct: 2613 RYAVTEQDRVLQF-AAFAFDVSVEECFSSLCNGAALVIRDDSWLASMAEFIALARQNRIT 2671
Query: 200 TLLRSILMY--LALGPASRPL-RRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ L + LA PL L+L + E + K ++F+ + +L N YG
Sbjct: 2672 VMFLPTLFWSELAARDNGLPLPDGLRLIIIGSEAVKKNAIQDWFRQETYQ--LRLLNAYG 2729
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE VT E D IGRP+ N +YLLD P GE+++ G
Sbjct: 2730 PTE--NTVTATCKEILSPAD---DRSIGRPIRNTRVYLLDRNRQPVPLGCVGEMYIGGVG 2784
Query: 317 LAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY+ RF + P+ R+YRTGD L+ G + + GR D QVKIRG
Sbjct: 2785 VARGYLNRLALSEERFIPDVFNPVPD-ARMYRTGDLARYLLDGELEFLGRNDQQVKIRGF 2843
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
RV+L E+E L + P V + VL LD G + L A + L + L
Sbjct: 2844 RVELGEIETRLVEYPAVQEAAVL--ALDDGQDKRLVAYVVAEANEGLAARLREYLSAVLP 2901
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P + ++S P NGK+DR+ L
Sbjct: 2902 DYMIPVAFVRLDSFPQTPNGKLDRRAL 2928
Score = 177 bits (431), Expect = 9e-43
Identities = 140/455 (30%), Positives = 221/455 (48%), Gaps = 28/455 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++LLA KAG AYVP++ ++P+ R+T+IL D+ PS+V+ D++ ++ +++ V +
Sbjct: 350 VVSLLAVLKAGGAYVPLDSTYPRERLTYILSDSAPSVVLVDEAGRAALGEQALVGVTVLD 409
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
Q D+P + LT +A V+YTSGSTG PKGV + + AI R
Sbjct: 410 PNIQ------LDQPDSNPQIPALTPQHLAYVIYTSGSTGQPKGVMVEHQAIYQRYLGFND 463
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T+ + + + + A F SV + + L +G L+I + V + R +
Sbjct: 464 TYAVTSQDRLLQF-AAFAFDVSVEDFFSSLCNGATLVIRDDSWLASIPEFVALTRQYRIT 522
Query: 200 TLLRSILMY--LALGPASRPLRR-LKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ L + LA PL L+L + GE + K ++F+ G+ +L N YG
Sbjct: 523 VMSLPTLFWSELAARDNGLPLPDCLRLIIIGGEAVKKSAIQDWFRQAGHRP--RLLNGYG 580
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDE--ELSPTRDSEPGEVWVAG 314
TE VTY D L IGRP N IYLLD+ EL P GE+++ G
Sbjct: 581 PTENTVTVTY-----KDVLSPEDARSIGRPAKNARIYLLDKYGELVPA--GCVGEMYIGG 633
Query: 315 ANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
+A GY+ RF + + +R+YR+GD L G + + GR D QVKIR
Sbjct: 634 VGVARGYLNRPALSVERFMLDTF-SPVSGERMYRSGDLARYLPDGDLEFLGRNDEQVKIR 692
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L E+E L + P V + VL D+G ++ +V K A + L +
Sbjct: 693 GFRIELGEIETRLTEHPAVQEAAVLALDGDQGK-RLVAYVEAKAN-EGLAVDLREYLSAI 750
Query: 432 LTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYEN 465
L YM+P + +++ P +GK+DR+ L EN
Sbjct: 751 LPDYMVPAAFVRLDTFPQTPSGKLDRRALPAPGEN 785
Score = 165 bits (400), Expect = 5e-39
Identities = 158/574 (27%), Positives = 255/574 (44%), Gaps = 50/574 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP++P +P R+THIL D P +++ D + + F+
Sbjct: 4652 VVGLLAVLKAGAAYVPLDPDYPGERLTHILADVSPVILLADAVGRTVLGENVLTGLTVFD 4711
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ D+P + LTS +A V+YTSGSTG PKGV + + + +++
Sbjct: 4712 P------NTLFDQPDSNLQIPELTSRHLAYVIYTSGSTGTPKGVMVEHRQLVSQITSLNT 4765
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIERL- 195
+ + S+ + + +F EI+ + G L++ + + Q +L ++
Sbjct: 4766 KWSLNASDRLLQFCNP-SFDVCASEIFCAITQGAQLVLRTNQWLLSAQAFWRLCESYKIT 4824
Query: 196 -VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK-LAN 253
+ +P I+ + G + LR + + GE + E ++ Y LAN
Sbjct: 4825 YIAIPAQFWRIISNVDKGDIYQGLRIICI---GGEAIPDH---ELQRWLATHGEYPVLAN 4878
Query: 254 FYGSTEVMGDVTYYVL-EGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE T L EG Q ++ IGRPL N +YLLD + P GE+++
Sbjct: 4879 CYGPTEATITTTTSCLNEGMGQANI-----IGRPLPNTRVYLLDVQGQPVPLGVEGELYI 4933
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
G +A GY A F +P + P R+YRTGD L G + + GR D QVK
Sbjct: 4934 GGVGVARGYFNRAELTAEYFLTDPFSDNPN-ARMYRTGDLVRYLPDGNLEFLGRNDHQVK 4992
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
IRG RV+ E+E L + P V + VVL G + + ++ +V + R A + L
Sbjct: 4993 IRGFRVEPGEIEARLVEHPAVSQSVVLALG-EGQDKRLVAYVVAQADERL-ANSLRTHLS 5050
Query: 430 SALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
+ L YM+P + +++ PL NGK+DR+ L +N A A +
Sbjct: 5051 AILPDYMVPSAFVRLDAFPLTPNGKLDRRAL----PEPDNEAFARQAYEAPQGETEIVLA 5106
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
+LG +S F+ LGG+SL ++ + RG ++
Sbjct: 5107 AIWC-------ELLGIE---QVSRHDNFFALGGHSLLAMRMMNLAAGRGLIFTLNALFQF 5156
Query: 549 STLGEVLSKMSTD----PNGGADSKEATFTAVPM 578
L E+ SK+++D P A S T +P+
Sbjct: 5157 PVLSELASKITSDLLSQPRSSAISVRPGGTGLPL 5190
>UniRef50_Q5Z1T0 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Nocardia farcinica|Rep: Putative non-ribosomal
peptide synthetase - Nocardia farcinica
Length = 1701
Score = 190 bits (464), Expect = 9e-47
Identities = 146/450 (32%), Positives = 224/450 (49%), Gaps = 36/450 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA K+GAAY+P++P++P+ RI ++++DAEP+LV+ V FA+ E
Sbjct: 556 VVAMLAVLKSGAAYLPIDPAYPEDRIEYLVEDAEPALVL------------GPVEFAAAE 603
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + + P DA+ + PL ++A V+YTSGSTG PKGV + ++AI + F
Sbjct: 604 SAAADLPDTA---PTDADRVRPLLPGNLAYVIYTSGSTGKPKGVPVPHAAIAEHV-ESFT 659
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+E+ + ++++F S+ +++ L G L++ + RD + ++ R V
Sbjct: 660 AEWGMTAEDRLLQSSSVSFDASLLDLFVTLSLGARLIVPKPDAFRDIAYVADLITRRGVT 719
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V ++ S+L L P R L+ GE L E+A +F F E L N YG
Sbjct: 720 VLHMVPSMLSTFLLLPEVSEWRALRHVPVGGEALPGEVADKFAGVFDAE----LRNHYGP 775
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + T+ +EG + +PIG P N Y+LDE L GE+++ G L
Sbjct: 776 TEAVVCSTHMPVEGPQGTGV---VPIGVPNRNVYTYVLDEALQLVPAGVVGELYLGGDQL 832
Query: 318 AAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY+G A RF +P RLYRTGD G + + GR D QVK+RG R
Sbjct: 833 ARGYLGRPELTAQRFVADPFTPG---ARLYRTGDLVRRNHFGELEFVGRADEQVKVRGFR 889
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK----PGARTSAQHIEGKLRS 430
++L EVE A+A P V CVV+ P + +V G + + +
Sbjct: 890 IELGEVEAAVATHPAVGHCVVVVAEDPAVGPMLAAYVVPAADEIAGGEIDLEEVRAHAAA 949
Query: 431 ALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
L YM+P V IPL VNGK+D++ L
Sbjct: 950 VLPQYMVPSAFAVIPEIPLTVNGKLDKRAL 979
>UniRef50_Q9F5J4 Cluster: SimH; n=5; Streptomyces|Rep: SimH -
Streptomyces antibioticus
Length = 997
Score = 190 bits (464), Expect = 9e-47
Identities = 169/566 (29%), Positives = 260/566 (45%), Gaps = 49/566 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+LA K GA ++P++P +P RI ++L DA P++V +A + ++
Sbjct: 471 VTAVLAVAKTGAGFLPIDPGYPADRIAYMLGDAGPAVVCTTRTAAAVLPQDVSGIVLDDP 530
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+A EA S ++P+ +E AP+ ++A V+YTSGSTG PKGV ++++ + N + +
Sbjct: 531 AVAAEAAGLSDEDPVASEHWAPVPPAALAYVIYTSGSTGRPKGVAVTHAGLANLVAAKVE 590
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALL-----ILSRETTRDPQKLVNIER 194
+ I + + +F + E+ + G L+ IL+ + + I
Sbjct: 591 RMDVDEQSRILQFASP-SFDAFMTELLATIGAGATLVVPPPGILAGDHLAEVLVAERITH 649
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+VL P S+ P S P L+ V +GE S +L + + G ++ N
Sbjct: 650 VVLPPVAAASV------SPESLP--DLRSLVLAGEASSGDLIARW------APGRRVINA 695
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE T S+ L T PIG P+ A Y+LDE L P PGE+++ G
Sbjct: 696 YGPTEATVCATM-----SEPLSADATPPIGGPIPGAACYVLDEALRPVPAGVPGELYLGG 750
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIR 371
A LA GY+G G A RF NP A + R+YRTGD G + + GR+D QVK+R
Sbjct: 751 AGLARGYLGRPGMTAERFVANPFA--GDGSRMYRTGDLVSWRSDGGLDFLGRSDEQVKLR 808
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G R++L EVER L PGVD+ V + G I+ + GA + +
Sbjct: 809 GFRIELGEVERVLTNHPGVDRAVAVVREDGAGGRRIVVHLIPSAGAAPTMAELREHAGRF 868
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXX 490
L +M+P + +++ PL NGK+DR+ L DA A
Sbjct: 869 LPDFMVPGAFVLLDAFPLTPNGKLDRRAL--------PEPDAAPA-----PSGRAPSTPE 915
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
VLG A + F+ELGGNS+ +I I K R G + D + T
Sbjct: 916 EIALSRIFSEVLGVA---EVDADRNFFELGGNSMVAITVIQKARKAGLAISPKDLVMNPT 972
Query: 551 LGEVLSKMSTDPNGGADSKEATFTAV 576
+ E L+ ++ + EAT TAV
Sbjct: 973 V-EALAAIAGRTDQAPRRAEAT-TAV 996
>UniRef50_A0PRJ7 Cluster: Peptide synthetase Nrp; n=1; Mycobacterium
ulcerans Agy99|Rep: Peptide synthetase Nrp -
Mycobacterium ulcerans (strain Agy99)
Length = 3144
Score = 190 bits (464), Expect = 9e-47
Identities = 167/556 (30%), Positives = 263/556 (47%), Gaps = 34/556 (6%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+A+LA K GAAYVP++PS+P + +L D P+ ++ ++A + + P +
Sbjct: 2070 IAVLAIIKTGAAYVPLDPSWPPQQAELVLCDCAPTAIL-TETALQHVVADHDAPILQLDA 2128
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
L +D+P + + D +A V+YTSGSTG PKGV ++++ + RL+
Sbjct: 2129 L------DLSDQPGTGVDI-EVNDDDVAYVIYTSGSTGRPKGVEVTHANVM-RLFSATEG 2180
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIERL-V 196
S + ++ F SV E+WGPLL+G ++++ TR P ++L++ ER+ V
Sbjct: 2181 LVEFTSADRWTMFHSIAFDFSVWELWGPLLYGGCVVMVPYLETRTPRAFRELLSRERITV 2240
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L T L+ A A+ PL L+ + GE L+ + + G+ L N YG
Sbjct: 2241 LNQTPSAFRLLRDADAEAATPL-YLRYVIFGGERLTSSDLIPWIEAHGDSHP-DLINMYG 2298
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE VT+ L D L + IGRP+ + L D + GE+ VAG
Sbjct: 2299 ITETTVHVTFRRLRREDVLGGRGS-RIGRPIPDLECLLTDAAGNLVPLGVRGEICVAGPG 2357
Query: 317 LAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIRGHRV 375
LA GY+G PH +P +RLYR+GD G L G + Y GR D QV++ G R+
Sbjct: 2358 LAKGYLGQPELTGQRFVPHPFRPR-ERLYRSGDVGRRLPSGEIDYFGRLDHQVQLHGFRI 2416
Query: 376 DLLEVERALAQVPGVDKCVVLCYGL---DRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
+L EVE A V G+++ VV C+ + D P ++ +V T G + KL + L
Sbjct: 2417 ELGEVENA---VSGLEE-VVACHAMVRHDDAKPRLVAYVVTSTGEQLPINSSRQKLTARL 2472
Query: 433 THYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P ++ VES+PL NGK+D++ L A A + +
Sbjct: 2473 PGYMLPSAIVTVESLPLTANGKIDQRALPAPMVAAG----APSATPSETTDSTRNLAAST 2528
Query: 492 XXXXXTVGA-VLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
V A VLG + G F+++GG+S+ ++ K R G VE+ D T
Sbjct: 2529 VDQIRQVFAEVLGLPSVGA---DDNFFDIGGDSIYAVQLSAKARALGLAVEVQDLFQCQT 2585
Query: 551 LGEVLSKMSTDPNGGA 566
++ + M + GA
Sbjct: 2586 PEQLAAGMIRTGSAGA 2601
Score = 172 bits (419), Expect = 3e-41
Identities = 159/543 (29%), Positives = 246/543 (45%), Gaps = 50/543 (9%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+A LA ++G V + P+ P R+ ++ DA S V+ DD P VP + E
Sbjct: 568 VAALAIARSGVVVV-VNPTHPSARVADMITDAGVSRVVVDDQTRPL------VPVNAPEL 620
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
+A + +A M L P A + +TSGSTG PK V S+ A CN+L W+
Sbjct: 621 IAADRAG-AAVASMPPPQLDPAEP---AYLNFTSGSTGRPKAVTSSHRAFCNQLLWRRDE 676
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIER 194
F + + + A TF + EI+GPL+ G L+ E DP +V +I
Sbjct: 677 FGLGGDDAL-LQTAAPTFDIFMWEIFGPLVAGARLVFNPGEW--DPHSIVQRVRQSSITM 733
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
L +VP+ L +L LG L+ C GE LS L F + + L N
Sbjct: 734 LQIVPSQLDVLLEEPDLGQCMT----LRYVFCGGEPLSLALCRRFAAVLPHAE---LVNL 786
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE D ++ +E +D+ PIGRP+ N +Y++D E + GE+W+ G
Sbjct: 787 YGPTETTIDAIFWRVEVADEASW---APIGRPIANACLYVVDPEGALAAPGGEGELWIGG 843
Query: 315 ANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIR 371
A + GY+G A RF + P R+YRTGD G + + GR D Q+K+
Sbjct: 844 AGVTMGYLGSPAITAQRFRRDVRCAHPG-ARVYRTGDRVRQRPDGTLEFLGRMDRQLKVH 902
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGF-VTTKPGARTSAQHIEGKLRS 430
G R++ E+ER L + PGV VV G+ + + ++ P + + R+
Sbjct: 903 GVRIEPAEIERTLCEHPGVQHAVVTVKERAPGDKALAAYLISDSPNMELDLEAVLKTCRT 962
Query: 431 ALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L M+P + V +S+P GKVD L + + DA+V D+
Sbjct: 963 KLPATMVPAAVMVLDSLPRTSTGKVDMAALPAVPFAGAADADADVR-DVP---------Q 1012
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGA 548
+LGR L + F+ +GG+SL ++ I ++R+R G +++ DF+ A
Sbjct: 1013 RLIGLARIWEEILGRP---VLDPDADFFRIGGHSLAALRVIMRVRERMGVVLQMRDFVSA 1069
Query: 549 STL 551
TL
Sbjct: 1070 GTL 1072
>UniRef50_A0ACQ7 Cluster: Putative peptide synthetase; n=1;
Streptomyces ambofaciens ATCC 23877|Rep: Putative
peptide synthetase - Streptomyces ambofaciens ATCC 23877
Length = 3667
Score = 190 bits (464), Expect = 9e-47
Identities = 164/565 (29%), Positives = 261/565 (46%), Gaps = 43/565 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL +AG A+VP++P +P R +++DA V+ SA +G P A
Sbjct: 203 VIGLLGVLRAGCAFVPLDPHWPAARRAVVVEDAR---VVLQLSASGE--HAAGEPEAVAV 257
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+L + E P D++A V++TSGSTG PKG + + AI RL WQ
Sbjct: 258 DLGD--WRFGSRPSAGGEVAVP--GDALAYVIFTSGSTGRPKGAMIRHEAISERLLWQVH 313
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
++ ++K L+F SV EI+ PL+ G L++L RDP L+++ E+ V
Sbjct: 314 EILGFGHDDASLFKAPLSFDISVNEIFLPLVSGARLVVLRPGGERDPHHLLSVIAEQRVT 373
Query: 198 VPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
L+ S+L + L + S L L+ C GE L+ EL ++ F + + YG
Sbjct: 374 FTYLVSSMLDVLLEIAGDSGRLDSLRHVWCGGEVLTPEL----YERFRTRLDIPMYHGYG 429
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E V++ + G+ + + IG+ N +Y+LD+EL P GE++V G
Sbjct: 430 PAETTIGVSHVIYRGAAE---RLSTSIGKANPNTQLYVLDDELRPVPVGVGGELYVGGFL 486
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGH 373
L GYV A+RF NP A + RLYRTGD G++ + GR D QVKIRG
Sbjct: 487 LGRGYVNAPALTASRFVANPFA--DDGSRLYRTGDLARFAPDGSLDFLGRADNQVKIRGM 544
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR-TSAQHIEGKLRSAL 432
R+++ +VE LA+ PGV V+ G ++G+V G A ++ + L
Sbjct: 545 RLEIEDVEVGLAEHPGVRHTCVVAKRNSAGGTYLVGYVIPAAGHEDLRAADVKAWAGTHL 604
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P ++ + PL NGK+DR L + E+A +
Sbjct: 605 VEYMVPAHIVVMTRFPLTANGKLDRHAL----------PEPELAT----ASIVPPTTENE 650
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
V +L A G + F++LGG+S+ +I ++ LRD G +V ST+
Sbjct: 651 RAVCTAVATLLRLEAVG---VDQDFFQLGGDSILAISLLSALRDAGLHVTARQIFTHSTV 707
Query: 552 GEVLSKMSTDPNGGADSKEATFTAV 576
G + + + + D + +V
Sbjct: 708 GALAAVAAREDTAVVDHHDVATGSV 732
Score = 173 bits (422), Expect = 1e-41
Identities = 144/452 (31%), Positives = 216/452 (47%), Gaps = 31/452 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYD-DSAD--PSMFKESGVPFA 76
++AL+ AG AYVP++ ++P R+ +IL DA P +V+ + D + + +P A
Sbjct: 1689 VVALVGVVSAGGAYVPLDLAYPDERLRYILTDAAPQVVLVTPEHRDRFTRLLSRADLPTA 1748
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
L E S AD + P D A V+YTSGSTG PKGV + +S++ L
Sbjct: 1749 RVLVLGDE--SPPADPGPER---GPAGHDP-AYVIYTSGSTGRPKGVVVPHSSVVTLLAN 1802
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+ +++ V + +F +V E+WG L HG LL+ TR P + R
Sbjct: 1803 TGPDMGFGP-DDVWVQFHSFSFDFAVWELWGALAHGGELLVPEYGLTRSPVDFHRLVRER 1861
Query: 197 LVPTLLRSILMYLALGPASR----PLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
V L ++ + A R PL L+L V GE L ++ + G +L
Sbjct: 1862 GVTVLNQTPSAFYQFVEADRHAGEPLPALRLIVFGGEALDPGRLRDWVRRHGVH-APELV 1920
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE VT+ VL D PIG PL YLLD+ L P G ++V
Sbjct: 1921 NMYGITETTVHVTHRVLTAEDLAPGVDVSPIGAPLPGLVTYLLDDRLRPVPPGREGAIYV 1980
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVK 369
AG ++ GY+G A RF NP + R+Y TGD + G + + GR D QV+
Sbjct: 1981 AGDQVSLGYLGRPALTAGRFVANPFT--GDGTRMYHTGDLARRTLDGELRFTGRADDQVQ 2038
Query: 370 IRGHRVDLLEVERALAQVPG-VDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
++G R++L EVE A+ ++ G VD V + G D ++G V P T+ L
Sbjct: 2039 LKGFRIELGEVEAAIRELDGVVDVAVTVADGGDHLVAHLVGEV---PADLTAL------L 2089
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L +M+P + + ++ +PL VNGK+DR+ L
Sbjct: 2090 SEKLPAHMVPRRTLPLDVLPLTVNGKLDRKAL 2121
Score = 139 bits (337), Expect = 2e-31
Identities = 146/465 (31%), Positives = 209/465 (44%), Gaps = 58/465 (12%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+I+AL A + GAAYVP+E P RI I+ DA P++ + + P + +G
Sbjct: 3144 SIVALFAVLRTGAAYVPLELDHPDERIAAIVADARPAVTLTVSAVAPRL---TG------ 3194
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSI---AIVLYTSGSTGIPKGVRLSYSAICNRLW 135
+L + A EP+ T AP + A +YTSGSTG PKGV Y+ + N L
Sbjct: 3195 -DLIELDRPLPAAEPL--VTFAPDDPHRLRHPAYTIYTSGSTGKPKGVVTEYAGLTNMLV 3251
Query: 136 -WQFRTF-PYSDSEEICVWKTALTFVDSVCEIWGPLL---HGRALLILSRETTRDPQKLV 190
Q R F P V++ A T + W LL G + I E RD LV
Sbjct: 3252 NHQRRIFEPVLAEHGHRVFRVAHTVSFAFDMSWEELLWLADGHEVHICDEELRRDAPALV 3311
Query: 191 ------NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFG 244
I+ + + PT + + L G P RR L + GE ++ L ++
Sbjct: 3312 EYCLAHGIDVINVTPTYAQQL---LGEGLLDDPGRRPALVLLGGEAVTPTL----WRRLA 3364
Query: 245 NEDGYKLANFYGSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTR 303
+G N YG TE + + E D + +G +DN +Y+LD L P
Sbjct: 3365 ETEGTVGYNLYGPTEYTINTLGVGTFECQDPV-------VGVAIDNTDVYVLDPWLRPLP 3417
Query: 304 DSEPGEVWVAGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLY 360
D PGE++V+G +A GY+G A+RF P +P R+YRTGD G + Y
Sbjct: 3418 DGVPGELYVSGIGIARGYLGQPAQTAHRFVACPFG-EPG-ARMYRTGDLVARRSDGNLTY 3475
Query: 361 AGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEI-----LGFVTTKP 415
GRTD QVKIRGHRV+L EVE A V + + +P++ L
Sbjct: 3476 LGRTDQQVKIRGHRVELGEVEAVFA----AHSAVRFAAAVAQPDPQVDGAYRLAAYLVLD 3531
Query: 416 GARTSAQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
GA + ++ +AL ++ P V+ IPL VNGK D + L
Sbjct: 3532 GA--DLAEVAAEVGAALPDFLRPTHYARVDGIPLTVNGKADTRAL 3574
>UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2;
Cystobacterineae|Rep: Non-ribosomal peptide synthase -
Stigmatella aurantiaca DW4/3-1
Length = 1443
Score = 190 bits (463), Expect = 1e-46
Identities = 167/570 (29%), Positives = 263/570 (46%), Gaps = 45/570 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I++ LA KAG A++ ++P P R+ IL DA P +V+ + + +
Sbjct: 594 IVSFLAVLKAGGAFLALDPDEPSERLRRILDDARPEVVLSAGELAGRLAELGRFTVVRVD 653
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E Q S + + + ET P ++A +LYTSGSTG PKG +++ +I N L W
Sbjct: 654 EQGQLLPS-ATGKRLRRET-GP---GNLAYILYTSGSTGQPKGTEITHRSIVNYLKWCVD 708
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRET-----TRDPQKLVNIER 194
+ + V + ++F ++ ++ PLL GRAL +L R T + +
Sbjct: 709 AYRLKAASGSPVIGS-VSFDGTLTSLFAPLLAGRALFLLPRGQEIDLLTSETYPEQDFSF 767
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ + P+ LR+ + LG A + L R V GE L A + + ++ N
Sbjct: 768 IKMTPSHLRA---FDGLGRARKVLERAHAAVLGGEGLH---AGDLATWREQRIATRIINE 821
Query: 255 YGSTEV-MGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + Y V +G + L IPIGRP+DN +Y+LD P PGE+ +
Sbjct: 822 YGPTEAAVACCVYDVPQGGEPLP--ERIPIGRPIDNTQLYILDRHRQPVPIGVPGELHIG 879
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQ---RLYRTGDFGT-LVKGAVLYAGRTDAQ 367
G LA GY+ A RF NP ++ RLYRTGD L G + + GR D+Q
Sbjct: 880 GTGLARGYLRRPDLTAERFIPNPFQSETSGSGGDRLYRTGDLARYLPDGRIEFLGRVDSQ 939
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
+KIRGHRV+ E+E ALA+ P V + V+ + P ++ +V K A A ++ +
Sbjct: 940 LKIRGHRVEAGEIEAALARHPRVVQAAVVLRHVPNSPPRLVAYVQAKALAEGDAAVLKEE 999
Query: 428 ----LRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSX 482
LR + YM+P EV + +PL +GK+DR+ L + A A
Sbjct: 1000 FRKFLRGQIPDYMIPGAFEVLDELPLTPSGKIDRKALPPL---------ATEAHGASALV 1050
Query: 483 XXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVE 541
+LG A +S + F+ELGG+SL +I I ++R G V
Sbjct: 1051 RTRGASETERQLEALFSELLGLEA---VSPNASFFELGGHSLLAITLIARIRSHLGIEVP 1107
Query: 542 ISDFLGASTLGEVLSKMSTDPNGGADSKEA 571
+++ T+ E L++ + +G + A
Sbjct: 1108 LNEIFERPTV-EDLARWIDEHSGALSALAA 1136
>UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3;
Bacteria|Rep: Amino acid adenylation domain - Pseudomonas
putida F1
Length = 5230
Score = 190 bits (463), Expect = 1e-46
Identities = 144/456 (31%), Positives = 229/456 (50%), Gaps = 25/456 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A KAG AYVP++P++P R+ ++++D+ V+ A P + VP A
Sbjct: 4678 VVGIFAILKAGGAYVPLDPAYPADRLAYMIEDSGLQRVL----AQPQVLASLPVP-AGVR 4732
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L+ E++ S+ A + ++ D++A V+YTSGSTG PKGV L +
Sbjct: 4733 VLSLESSDDSSQADPLACSPVTVSPDNLAYVIYTSGSTGKPKGVLLPQRNVLRLFTATDA 4792
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIERLV 196
F + S+++ + F SV EI+G LL+G L+I+ + T+R P+ +L+ E++
Sbjct: 4793 DFRFG-SDDVWSLFHSYAFDFSVWEIFGALLYGGRLVIVPQHTSRSPEAFYQLLADEQVT 4851
Query: 197 LV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
++ P+ + ++ RPL L+ V GE L + +F+ FG+ +L N
Sbjct: 4852 VLNQTPSAFKQLMAVATTAEPQRPLA-LRSVVFGGEALDVNSLAPWFERFGDRQP-QLVN 4909
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE V+Y L +D L + P+G P+ + + Y+LD +L+P GE++V
Sbjct: 4910 MYGITETTVHVSYRPLSRAD-LGKAASSPMGVPIPDLSWYVLDGDLNPVAKGCIGELYVG 4968
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
A LA GY+ A RF +P RLYRTGD G + YAGR D QVKI
Sbjct: 4969 RAGLARGYLKRSDLSATRFVPDPFGAPGG--RLYRTGDLARYHADGVIEYAGRIDHQVKI 5026
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR- 429
RG R++L E+E L P V + +VL G + + A + +LR
Sbjct: 5027 RGFRIELGEIEARLQAQPQVREALVLAQEGATGQQLVAYLIPAAEVALEQQAGLRAQLRE 5086
Query: 430 ---SALTHYMMP-QVIEVESIPLLVNGKVDRQGLLK 461
AL YM+P ++ ++ PL NGK+DR+ L K
Sbjct: 5087 QLKEALPDYMVPAHLLLLDRWPLTANGKLDRKALPK 5122
Score = 173 bits (420), Expect = 2e-41
Identities = 133/447 (29%), Positives = 213/447 (47%), Gaps = 22/447 (4%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELA 82
++ T+KA A Y+P++P PQ R++HI+ + +++ +++ E+ +
Sbjct: 3154 MVGTFKAAAGYLPLDPGLPQQRLSHIVALSRTPVLLCTEASQAQA--EALLDALDEARRP 3211
Query: 83 QEATSHSADEPMDAETLAPLTS--DSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
Q + D P AE S +A V+YTSGSTG PKGV + + + N Q
Sbjct: 3212 QLLVLETLDRPGSAEHDPQRYSGPQHLAYVIYTSGSTGQPKGVMVEQAGMLNN---QLSK 3268
Query: 141 FPYS--DSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV 196
PY +++ + +F SV + L G + I+ E DP+ L+ E+ +
Sbjct: 3269 VPYLALGPDDVIAQTASQSFDISVWQFLAAPLFGGCVQIVPNELAHDPEALLQQVREQRI 3328
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + S++ + PA + L+ + +GE L+ ELA ++ + + + L N YG
Sbjct: 3329 SVLESVPSLIQGMFQAPAIA-VPSLRWMLPTGEALAPELARQWLQRYPDVG---LVNAYG 3384
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E DV ++ ++ + +Y +PIG P DN +Y+LD L GE+ VAG
Sbjct: 3385 PAECSDDVAFFRVDLASTQGVY--LPIGSPTDNNRLYVLDAALELAPLGVTGELCVAGTG 3442
Query: 317 LAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHRV 375
+ GYVG PH +RLYRTGD VL Y GR D QVKIRG R+
Sbjct: 3443 VGRGYVGDPLRTAQAFIPHPCGAPGERLYRTGDLARRRADGVLEYVGRVDHQVKIRGFRI 3502
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA--QHIEGKLRSALT 433
+L E+E AL V + VV+ G P+++ + A Q ++ L++ L
Sbjct: 3503 ELGEIEAALLDSDQVREAVVMAQPGANG-PQLVAYCVADDAVAADALKQQLKASLKARLP 3561
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P + + +PL NGKVDR+ L
Sbjct: 3562 DYMVPVHWVLMARLPLTPNGKVDRKAL 3588
Score = 171 bits (416), Expect = 6e-41
Identities = 137/452 (30%), Positives = 212/452 (46%), Gaps = 31/452 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LLA KAG AYVP +P +PQ R+ ++L D+ L++ + P + +++ V + +
Sbjct: 573 IVGLLAILKAGGAYVPFDPEYPQERLAYMLDDSGVQLLLTQQALLPRLPQDTQVRYLVLD 632
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A+E S P A L +D++A V+YTSGSTG KGV +S+ A+ N + +
Sbjct: 633 QAAEELARFSTTAPP-----AQLNADNLAYVIYTSGSTGRSKGVTISHGALANYVQAALQ 687
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ V T + ++G L G L +++ + + D ++ V
Sbjct: 688 RLALGRVASMAVVSTLAADLGHT-TLFGALCSGSCLHVIALDISLDAERFAAYMHAHAVD 746
Query: 198 VPTLLRSILMYLALGPASRPLRRL--KLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
V ++ S L L GP P R L + V GE L + + + L N Y
Sbjct: 747 VLKIVPSHLQALLDGP--HPARALPQRALVLGGEACPAGLMAHLAQLAPH---CTLFNHY 801
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE +E +P+GRPL N Y+LD L P GE+++AGA
Sbjct: 802 GPTETTVGALADAVEVPSATG---RVPLGRPLANMQAYVLDASLQPLSTGCQGELYLAGA 858
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIRG 372
+A GY A RF NP R+YRTGD L G V Y GR D QVKIRG
Sbjct: 859 GVARGYHRRAAMTAERFVPNPFGAAG--SRVYRTGDLARQLANGQVDYLGRVDHQVKIRG 916
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
+R++L E+ L + P V V + +G I+ +V P ++ A + ++AL
Sbjct: 917 YRIELGEITDTLKRQPRVHDAVAVIHGTGSA-ARIVAYVV--PDSQADASQVLADAQAAL 973
Query: 433 TH----YMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P + + + +PL +NGK+D + L
Sbjct: 974 ARQLPDYMLPSRFMALPGMPLTLNGKLDLRAL 1005
Score = 142 bits (344), Expect = 3e-32
Identities = 145/553 (26%), Positives = 242/553 (43%), Gaps = 51/553 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG A++P++P +P R+ ++++D+ L++ P + ++G+ +
Sbjct: 1630 VVGLLGILKAGGAFLPLDPQYPAERLAYMMQDSGIDLLLSHSRVLPGLDVQAGMRTLLLD 1689
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ ++ AD A T+A L ++A V+YTSGSTG PKGV +++ + +
Sbjct: 1690 QRVEQP---GADH---APTVA-LNPQNLAYVIYTSGSTGQPKGVAVAHGPLAMHCLATGQ 1742
Query: 140 TFPYSDSEEICVWKTALTFV-DSVCEIW-GPLLHGRALLIL-----SRETTRDPQKLVNI 192
+ + ++ + L+F D E W L+ G +LL+ S E T + + +
Sbjct: 1743 WYEMTPADRELHF---LSFAFDGAHERWLTSLVMGGSLLLRDDELWSPERTYEEIRRHGV 1799
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
P L+ + + A P+R L+ G+ + + + + + + +
Sbjct: 1800 TMAGFPPAYLQQLAEHAAHAGNPPPVR---LYSFGGDAMPR---ATYERVQQSLQPQVMI 1853
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE + + D D PIG+P+ + +LD L G++++
Sbjct: 1854 NGYGPTETVVTPMVWRTRAGDHCDS-AYAPIGQPVGERSACVLDAALGLLPAGVAGQLYL 1912
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVK 369
GA LA GY+G G A RF +P T E RLYRTGD L G Y GR D QVK
Sbjct: 1913 GGAGLARGYLGRPGLTAERFVPDPFGT--EGARLYRTGDQVRLRADGQFDYLGRIDNQVK 1970
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNP----EILGFVTTKPGARTSAQHIE 425
IRG RV+L E+E L V + VV+ G +L G + ++
Sbjct: 1971 IRGFRVELGEIEACLLACAEVREAVVVAVDGPSGKQLAAYLVLADSIAAHGPAEQREQLK 2030
Query: 426 GKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXX 484
LR +L YM+P + +E +PLL NGK+DR+ L D S
Sbjct: 2031 AALRQSLPDYMLPTHWLVLEQLPLLPNGKLDRKALPAP----------------DFSALQ 2074
Query: 485 XXXXXXXXXXXXTVGAVLGRAAR-GTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEIS 543
+ A+ R + + + F+ELGG+S+ SI +++ R G
Sbjct: 2075 QAYVAPRNALEQRLAALWQRVLKLPQVGVSDNFFELGGDSIISIQLVSRARQDGLLFSAR 2134
Query: 544 DFLGASTLGEVLS 556
D T+ + S
Sbjct: 2135 DLFEHQTVAALAS 2147
>UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp.
B14905|Rep: Peptide synthetase - Bacillus sp. B14905
Length = 1055
Score = 190 bits (463), Expect = 1e-46
Identities = 152/547 (27%), Positives = 259/547 (47%), Gaps = 37/547 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
TI++LL KAG YVP++PS+P+ R ++L D +I + + + F S
Sbjct: 117 TIISLLGVLKAGGVYVPIDPSYPKERCQYLLHDTGAPFIITKNEYNDLLNDLIHNEFQSR 176
Query: 79 EELAQEATSHSADEPMDAETL-APLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
L T + + + E L L +A ++YTSGSTG PKGV L ++A+ N +
Sbjct: 177 TVL----TINQMESGLSQEDLPCNLLPSDLAYIIYTSGSTGKPKGVLLKHTAVINLITDN 232
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLIL------SRETTRDPQKLVN 191
R + +S E++ + +F SV E + G L +L S E D
Sbjct: 233 QRIY-HSTEEDVFSQFISYSFDPSVTETFTAFFSGARLHMLASIERLSIEAFADMIAREQ 291
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ + + +L + + L L+ GE L + ++ + FG ++
Sbjct: 292 VTTATVPNAFFTQLATHLPIDYRDK-LMTLQYLSVGGEALLPAIVQKWQEKFGYST--EI 348
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLL--DEELSPTRDSEPGE 309
N YG TE +Y+ ++ S D+ +IPIGRP+ N +Y++ DE+L P + GE
Sbjct: 349 INVYGPTECTVLTSYFKIK-SQLTDMQSSIPIGRPIANYEMYVVNKDEQLCPVHVT--GE 405
Query: 310 VWVAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQV 368
+ +AGA LAAGY+ PH +P+ Q++YRTGD L+ G + + GR D+Q+
Sbjct: 406 LCIAGAGLAAGYLHQPEKTAEAFVPHLFKPD-QKMYRTGDLVRLLPSGVIEFVGRKDSQI 464
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L E+E L+ P + + VV+ + G + + T G + Q + L
Sbjct: 465 KVRGFRIELGEIETVLSNHPIIQESVVIAKKMSDGQNHLFAYYTAANGIQLEEQVLRDYL 524
Query: 429 RSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
+ L YM+P+ IE+ +PL GK+DR+ L + E+ + + VA + D
Sbjct: 525 NNLLPDYMVPERFIELLEMPLSPTGKIDRKQLATLDESLSRS-HLYVAPENDTQHLLANA 583
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLG 547
VLG + G + F+ +GG+SL + + +++ +++I DF
Sbjct: 584 WEY----------VLGNSPIG---IHDNFFHIGGHSLKVLEILVQVKKHIPFLKIQDFFQ 630
Query: 548 ASTLGEV 554
T+ E+
Sbjct: 631 FQTIAEL 637
>UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes:
ATP-dependent isoleucine adenylase (IleA) (Isoleucine
activase); ATP-dependent D-phenylalanine adenylase
(D-PheA) (D-phenylalanine activase); ATP-dependent
histidine adenylase (HisA) (Histidine activase);
ATP-dependent D-aspartate adenylase (D-AspA) (D-aspartate
activase); ATP-dependent asparagine adenylase (AsnA)
(Asparagine activase); Aspartate racemase (EC 5.1.1.13);
Phenylalanine racemase [ATP hydrolyzing] (EC 5.1.1.11)];
n=3; Bacillus|Rep: Bacitracin synthetase 3 (BA3)
[Includes: ATP-dependent isoleucine adenylase (IleA)
(Isoleucine activase); ATP-dependent D-phenylalanine
adenylase (D-PheA) (D-phenylalanine activase);
ATP-dependent histidine adenylase (HisA) (Histidine
activase); ATP-dependent D-aspartate adenylase (D-AspA)
(D-aspartate activase); ATP-dependent asparagine
adenylase (AsnA) (Asparagine activase); Aspartate
racemase (EC 5.1.1.13); Phenylalanine racemase [ATP
hydrolyzing] (EC 5.1.1.11)] - Bacillus licheniformis
Length = 6359
Score = 190 bits (463), Expect = 1e-46
Identities = 138/446 (30%), Positives = 224/446 (50%), Gaps = 32/446 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +LA KAG AY+P++P +P+ RI ++++D+ S+++ AD K+ V F +
Sbjct: 3064 IVGMLAVLKAGGAYLPIDPEYPEDRIRYMIEDSGISILL--KKAD----KQIDVDFTCID 3117
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDS-IAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ M AE L + S +A V+YTSGSTG PKGV +++ +I N L+W+
Sbjct: 3118 -----MNEKGLAKDMAAENLGHTSGSSDMAYVIYTSGSTGKPKGVMVNHQSIVNTLYWRK 3172
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+++ YS + + + + +F SV +I+ L+ G A L+L R+ +P++++ + R
Sbjct: 3173 QSYGYS-TADATLQVPSFSFDSSVEDIFTTLISG-AKLVLIRDLRMNPREIIGVLRTHKA 3230
Query: 199 PTLLRSILMYL-ALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
LL YL L +PL L+ +GE ++ L + F+ N KL N YG
Sbjct: 3231 TNLLAVPSFYLNLLDTIEQPLDDLRFVTVAGEGFNESLIRQHFEKLPN---VKLFNEYGP 3287
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T L D+ + IGRP+ N +Y+L+ PGE+ ++G L
Sbjct: 3288 TENSVCSTRGELRKDDE-----KVVIGRPISNHKVYILNHNQQLLPLGTPGELCLSGEGL 3342
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ +F NP A + +YRTGD L G + Y GR D QVKIRG R
Sbjct: 3343 ARGYLNRPDLTLEKFVPNPFAPG---ESMYRTGDLARFLPDGQIEYLGRIDHQVKIRGFR 3399
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L ++ G+D V+ G + ++ A + L L
Sbjct: 3400 IELGEIENQLLKIEGIDAAAVMAREDQAGGKYLCAYIVADKAA--GVADVRKCLLKELPD 3457
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM+P ++++ +PL NGK+DR+ L
Sbjct: 3458 YMVPSYFVKLDQLPLTANGKIDRKAL 3483
Score = 179 bits (436), Expect = 2e-43
Identities = 126/448 (28%), Positives = 228/448 (50%), Gaps = 34/448 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ ++ KAG AY+P++P +P+ RI ++L+D+ ++++ D D + V
Sbjct: 5611 VVGIMGILKAGGAYLPIDPDYPEERIKYMLEDSGAAIILADHKQDLGTLHQEAV------ 5664
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL + +S+ AD A +DS+A ++YTSGSTG PKGV + + N + W R
Sbjct: 5665 ELTGDFSSYPADNLEPAGN-----ADSLAYIIYTSGSTGKPKGVMIRQRGLVNYITWADR 5719
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP--QKLVNIERLVL 197
+ + + ++ +++ F +V I+ PL+ G +++ +P +K+ ++ +
Sbjct: 5720 VYVQGEQLDFALY-SSIAFDLTVTSIFTPLISGNRVIVYRHSEDGEPLIRKVFRDQKAGI 5778
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + + + + ++RL + GE L ELA E + F ++ N YG
Sbjct: 5779 VKLTPSHLSLVKDMDASGSSIKRL---IVGGEDLKTELAKEITERF--HHNIEIYNEYGP 5833
Query: 258 TE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE V+G + Y G D+ ++PIG+P N +Y+LDE GE++++G
Sbjct: 5834 TETVVGCMIYQYDAGWDR---QVSVPIGKPASNVQLYILDERQEVQPVGIAGELYISGDG 5890
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
+A GY+ + +F NP +R+YRTGD + G + Y GR D QVKIRG+
Sbjct: 5891 VAKGYLNKPELTSEKFLPNPFLPG---ERMYRTGDLAKMRPDGHIEYLGRIDHQVKIRGY 5947
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEIL-GFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+E L + + + V D+ N ++L +V ++ + + I+ L L
Sbjct: 5948 RIELGEIEHQLLRHSDIKEAAVAA-KTDQNNDQVLCAYVVSE--RDITQKDIKTFLAKEL 6004
Query: 433 THYMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM+P +++++ +PL NGKVD + L
Sbjct: 6005 PEYMVPSYLLKLDELPLTPNGKVDLKAL 6032
Score = 168 bits (409), Expect = 4e-40
Identities = 136/447 (30%), Positives = 219/447 (48%), Gaps = 35/447 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAG AY+P++P++P+ RI +IL D++ ++ ++ ++ K+ F
Sbjct: 1560 IIGLLGILKAGGAYLPLDPAYPEDRIKYILGDSQTKFLL----SEEALIKKRA--FIKEA 1613
Query: 80 ELAQEATSHSADEPMDAETLAPLT-SDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
++ DA L P++ S +A ++YTSGSTG PKGV + + N +
Sbjct: 1614 DMINIDIHDKQIAAQDAAQLEPVSRSGDLAYIIYTSGSTGKPKGVLIEQKGLSNLVSAVV 1673
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL--V 196
+ + + + +L+F S EI+ L G AL++ +E Q L + R +
Sbjct: 1674 KLMHLNTGSRV-IQFASLSFDASAFEIFPALAAGSALVLGRQEEMMPGQPLTSFLRQYNI 1732
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
TL ++L L L LK+ V +G S+ELA ++ GN N YG
Sbjct: 1733 THATLPPTVLDVL----NESGLENLKVIVSAGSACSEELAK---RWSGNR---LFINAYG 1782
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T + EGS + P IG P+ N +Y+LD+ P GE+ V G +
Sbjct: 1783 PTETTVCATAGIYEGSGR----P--HIGSPIANTNVYVLDQNQKPVPTGVVGELCVGGMS 1836
Query: 317 LAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
LA GY+ A +F +P A+ +RLYRTGD L G + + GR D QVKIRG+
Sbjct: 1837 LARGYLNRPELTAEKFISHPFASG---ERLYRTGDLARWLPDGHLEFLGRIDHQVKIRGY 1893
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L ++ +D+ V+ D + + ++ +K ++ I L L
Sbjct: 1894 RIELGEIENQLLKLDKIDEAAVIARKDDDHSDYLCAYIVSKED--WTSTEISEWLEKELP 1951
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
HYM+P + ++ +PL N KVDR+ L
Sbjct: 1952 HYMIPAYFVRLDKLPLTSNDKVDRKAL 1978
Score = 167 bits (406), Expect = 1e-39
Identities = 130/447 (29%), Positives = 213/447 (47%), Gaps = 24/447 (5%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F I+ ++ KAG AY+P++P P+ RI +L D + +++ A + E+ +
Sbjct: 520 FEMIIGIIGILKAGGAYLPIDPETPKHRIAFMLSDTKAGVLLAQGKAADGIDCEADIIHL 579
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLS-YSAICNRLW 135
+ +A + D S A ++YTSGSTG+PKGV YSA R+
Sbjct: 580 D-KGVADGFSKKRLSSVND--------SGDTAYIIYTSGSTGMPKGVVTPHYSAA--RVV 628
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
++ + I + + +F SV +I+G LL+G +L+++ +ET + +L + +
Sbjct: 629 KNTNYIDITEDDAI-LQLSNYSFDGSVFDIFGALLNGASLVLIEKETVLNTHELAEVIKK 687
Query: 196 VLVPTLLRSILMYLALGPASRP-LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
V + + ++ L + L +L+ GE S + + G + KL +
Sbjct: 688 EQVSVMFITTALFNTLADINIGCLAKLRKIFLGGERASIPHVRKVLNHVGRD---KLIHV 744
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE TYY + D D TIPIG PL N ++ ++DE PGE+ +AG
Sbjct: 745 YGPTESTVYATYYFINEID--DEAETIPIGSPLANTSVLIMDEAGKLLPIGVPGELCIAG 802
Query: 315 ANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
L+ GY+ PH P +RLY+TGD L G + + GR D QVKIRG
Sbjct: 803 DGLSKGYLNREELTAEKFIPHPFIPG-ERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGF 861
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E L +++ +V + P I ++T S ++G L L
Sbjct: 862 RIELGEIESRLEMHEDINETIVTVREDEESRPYICAYITA--NREISLDELKGFLGEKLP 919
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P ++++ +PL NGKVDR+ L
Sbjct: 920 EYMIPAYFVKMDKLPLTKNGKVDRKAL 946
Score = 156 bits (379), Expect = 2e-36
Identities = 128/451 (28%), Positives = 212/451 (47%), Gaps = 31/451 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+++LA KAGAAYVP+EP R IL D+ ++++ S KE+ V FA
Sbjct: 4096 IISMLAVLKAGAAYVPIEPEQLAKRTNEILSDSRAAILLVKGSV-----KEN-VAFAG-- 4147
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E+ A D + + A ++D A ++YTSGSTG PKGV + + + N W +
Sbjct: 4148 EIVNVADG-LIDAKVASNLSASGSADQNAYIIYTSGSTGKPKGVFVRHGNVVNYTTWFMK 4206
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+++++ + ++ F I+ LL G L I +E + + + I
Sbjct: 4207 EAGLTENDK-AMLVSSYAFDLGYTSIFSALLSGSELHIARKECYTNAHRALKYIKENGIT 4265
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ L P+L +I + A +P L+L V GE ++ F+ + + + + N
Sbjct: 4266 YIKLTPSLF-NIFVNDPGFSAEKPCATLRLVVLGGEMINTRDVETFYNQYPD---HVVMN 4321
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIP-IGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE + V++ + LD + P IG P+ N Y+LDE + + GE+ +
Sbjct: 4322 HYGPTETTIGSVFKVID-PEHLDSFKECPVIGTPIHNTNAYVLDENMKLLPEGVYGELCI 4380
Query: 313 AGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVK 369
AGA + GYV +F +NP A ++YRTGD L G + AGR D QVK
Sbjct: 4381 AGAGVTGGYVNRPDETKEKFIENPFAPH---TKMYRTGDLARRLSDGNIELAGRIDTQVK 4437
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG+R++ E++ L + + + +G ++ + T A + I L
Sbjct: 4438 VRGYRIEPEEIKNRLLAHDDIKEAFIAAREDHKGAKQLCAYFTA--DAELPFEDIRTYLM 4495
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P +++E +PL NGK+D L
Sbjct: 4496 HELPEYMIPSSFVQIEKMPLSANGKIDTAAL 4526
>UniRef50_Q45R85 Cluster: Peptide synthetase; n=2;
Actinomycetales|Rep: Peptide synthetase - Streptomyces
fradiae
Length = 6292
Score = 190 bits (462), Expect = 2e-46
Identities = 145/458 (31%), Positives = 227/458 (49%), Gaps = 29/458 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESG-----VP 74
++A+LA K+GAAY+ ++P P R ++IL D P V+ + ++ G VP
Sbjct: 4244 VVAVLAVLKSGAAYLAVDPDHPAERTSYILHDCRPVAVLSTTAVRETLHGTVGEAVGEVP 4303
Query: 75 FASFEELAQEATS--HSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICN 132
+ +E A + HSA DA+ +PL D A +YTSGSTG PKGV +S++ + +
Sbjct: 4304 WLLLDEPATGGATAGHSAAPVTDADRRSPLLPDHPAYTIYTSGSTGRPKGVVVSHANV-S 4362
Query: 133 RLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI 192
RL R +++ + F SV E+WGPL HG L+++ + R P L+++
Sbjct: 4363 RLLTACRAAVDFGPDDVWTLFHSSAFDFSVWEMWGPLAHGGRLVVVPHDVARSPGDLLDL 4422
Query: 193 ---ERLVLVPTLLRSILMYLA----LGPASRPLRRLKLWVCSGETLSKELASEFFKYFGN 245
ER+ ++ + L L LG R L+ V GE L ++ + G
Sbjct: 4423 LGRERVTVLSQTPSAFLQLLRAESDLGVPPRTTAALRYVVFGGEALD---TAQLAPWRGR 4479
Query: 246 EDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDS 305
+L N YG TE VT+ L+ + +D + PIG PL++ ++LD+ L P
Sbjct: 4480 P--VRLVNMYGITETTVHVTHLELDDA-AVDRGGS-PIGTPLNDLRAHVLDQGLLPVPVG 4535
Query: 306 EPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAG 362
GE++VAG LA GY G A RF +P T R+YRTGD + G + Y G
Sbjct: 4536 VVGELYVAGPGLARGYRRRPGLSATRFVADPFDTGG---RMYRTGDLVRRTQDGGLHYVG 4592
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ 422
R+D+QVK+RG+R++ E+E A + P V + +G + ++ +V
Sbjct: 4593 RSDSQVKLRGYRIEPGEIEAAARRHPDVAQAATAVHGEGPQDRYLVCYVVPAADTDPDPH 4652
Query: 423 HIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L AL YM+P V+ + ++PL NGK+DR L
Sbjct: 4653 QVRAHLADALPGYMVPAAVVPLTALPLTPNGKLDRAAL 4690
Score = 167 bits (405), Expect = 1e-39
Identities = 142/446 (31%), Positives = 205/446 (45%), Gaps = 32/446 (7%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELA 82
+L +AG AY+P++P +P R+ +L+DA P+L++ +PS VP + E L
Sbjct: 544 ILGIQRAGGAYLPIDPEYPAERVGFLLRDARPALLVGGTGTEPSAADCPRVP--AEELLD 601
Query: 83 QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFP 142
A AD P L D A V++TSGSTG PKGV ++++ I Q +
Sbjct: 602 AGACRAEADVPPPGS----LPVDLPAYVVHTSGSTGRPKGVVVTHAGIAALAAEQIERYR 657
Query: 143 YSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVPTLL 202
+ AL F +V E+ L G L++ D +L + R + T L
Sbjct: 658 LGPGSRVAQL-AALGFDVAVAELVMALASGSCLVLPPHGLAGD--ELASFLRDRRITTAL 714
Query: 203 RSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMG 262
+ L P P L V GE L + + G ++ N YG TE
Sbjct: 715 APAAVLATLPPGDLP--DLTDLVTGGEQPPPALIARW------APGRRMFNVYGPTEA-- 764
Query: 263 DVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYV 322
T G D + IG P Y+LD L P D GE+++ G LA GY+
Sbjct: 765 --TVQATSGRCAADGDRSPDIGNPEAGVDAYVLDAALRPVPDGVTGELYLRGRGLARGYL 822
Query: 323 GGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG----AVLYAGRTDAQVKIRGHRVD 376
G G A RF +PH E R+YRTGD V G + + GR D QVKIRG RV+
Sbjct: 823 GRPGLTAGRFVADPHTGTGE--RMYRTGDLVRRVPGDGRTVLRFVGRADDQVKIRGFRVE 880
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTS--AQHIEGKLRSALTH 434
EVE ALA++ GV++ +V G+ ++G++T PG R S + + L L
Sbjct: 881 PGEVEAALAELDGVEQALVTVREERPGDRRLVGYLTPAPGHRGSLDVERLRRVLADRLPA 940
Query: 435 YMMPQVI-EVESIPLLVNGKVDRQGL 459
+++P ++ E+ IP NGKVDR L
Sbjct: 941 HLVPSLLMELAEIPRTANGKVDRAAL 966
Score = 165 bits (402), Expect = 3e-39
Identities = 135/383 (35%), Positives = 191/383 (49%), Gaps = 26/383 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ALL +AGAAYVP++P +P R+ IL D P ++ P++ +G A+
Sbjct: 5319 VAALLGVLRAGAAYVPLDPEYPDERVAAILADTRPVALLTTADCRPAI---TGAATAAGG 5375
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW-WQF 138
+ A + P+ E APL D A VL+TSGSTG PKGV +S + N L +
Sbjct: 5376 AVLLAADAAHGAGPVP-EPPAPLP-DQAAYVLHTSGSTGRPKGVVVSRGNLANLLADMRD 5433
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
R P +D + V T ++F + E++ PL+ G L++ R R P++L +
Sbjct: 5434 RLRPTADDRLVAV--TTVSFDIAALELFLPLVTGAGLVLADRGAARAPEELAAL-LTASG 5490
Query: 199 PTLLRSILMYLALGPASRP--LRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
TLL++ L + P LR L+ V GE L LAS E G +L N YG
Sbjct: 5491 ATLLQATPTTWQLLAETAPDALRGLRKLV-GGEALPASLASRL-----RELGGELVNVYG 5544
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T + PIGR L Y+LDE L+P ++ PGE+++AGA
Sbjct: 5545 PTET----TIWSTAAHLDRVTGSAPPIGRALRGTRAYVLDEWLNPRPENVPGELYLAGAG 5600
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGH 373
+A GY+G GG A RF +P R+YRTGD G + + GRTD QVK+RG
Sbjct: 5601 VARGYLGRGGLTAERFTADPFGAPG--SRMYRTGDLVRRRADGELEFLGRTDHQVKVRGF 5658
Query: 374 RVDLLEVERALAQVPGVDKCVVL 396
R++L E+E AL P V VV+
Sbjct: 5659 RIELGEIETALGAHPHVAGAVVV 5681
Score = 156 bits (378), Expect = 2e-36
Identities = 135/449 (30%), Positives = 209/449 (46%), Gaps = 23/449 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESG---VPFA 76
+ L KAGAAY+P++ +P RI +L D P+LV+ SA + E+ +
Sbjct: 3158 LTGLWGALKAGAAYLPVDVDYPAERIALLLGDGNPALVL-TTSAHAHLVPEAPGRQILCV 3216
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
A E + D+E P+ D++A VLYTSGSTG PKGV + ++
Sbjct: 3217 DLPGPADELARAAEGRVTDSELPRPVGPDTLAYVLYTSGSTGRPKGVAVGRGSLAAHAVR 3276
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+P D+ + + + + F +V ++ L+ G LL+ + + ++
Sbjct: 3277 SRDRYP--DAAGVSLLHSPVAFDLTVTALFTTLISGGTLLLAELDEHAQDSGVTYVKGTP 3334
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
LL + L A RP V GE L+ E+ ++ + ++ N YG
Sbjct: 3335 SHVALLNELPGVLD-ATAERP----GTLVLGGEPLTGEMLE---RWRAHHPQARVFNDYG 3386
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
+E + + +LE ++ +PIGRPL +++LD L P GE++V+G
Sbjct: 3387 PSETSVNCSDLLLEPGAEVP-EGLLPIGRPLPGNHMFVLDHLLQPVPVGVVGEIYVSGVG 3445
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYA-GRTDAQVKIRGH 373
+A GY G G A RF P+ R+YRTGD G ++ GRTD QVK+RG
Sbjct: 3446 VARGYHGRPGLTAERFLPCPYDAPGA--RMYRTGDLGRWRPDGIMECLGRTDDQVKVRGF 3503
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK--PGARTSAQHIEGKLRSA 431
RV+L EVE ALA V + V+ + G+ + G+V + P A L +A
Sbjct: 3504 RVELGEVEAALAARSDVARATVVVREDEPGDRRLTGYVVPEGGPDADFDPAAALRDLAAA 3563
Query: 432 LTHYMMPQVIEVES-IPLLVNGKVDRQGL 459
L YM+P I V S +P NGK+DR+ L
Sbjct: 3564 LPPYMVPAAIVVLSELPRTENGKLDRRAL 3592
Score = 142 bits (345), Expect = 2e-32
Identities = 131/459 (28%), Positives = 208/459 (45%), Gaps = 33/459 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESG-VPFASF 78
+ LL +AGAAY+P++ P R L D+ P+L++ D ++ E+G
Sbjct: 1599 VATLLGILRAGAAYLPLDTGHPADRNRRALSDSAPALLVTDAGRSRTLRGETGCAALVLG 1658
Query: 79 EELAQEATSHSADEPMDAETLA-PLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E + + A P D L P+T D+ A + TSGSTG PK V ++ A+ +
Sbjct: 1659 AEDTERELADRAPLPRDGAGLVRPVTGDNAAYTILTSGSTGRPKAVVVTRDALDAFVDRA 1718
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVL 197
T+ + E + + + F +V ++GPL G + + + + + ER
Sbjct: 1719 LDTYGDALGGEALL-HSPVAFDLTVVTLYGPLAAGGRVRVGDLDESGIARW--EKERPAF 1775
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + + G ++ P V +GE L + G G + N YG
Sbjct: 1776 VKATPSHLALLTEFGGSTAP----GTVVLAGEQLIGARLDRWRTRLG-ASGTTVLNSYGP 1830
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + + + + P +P+GRP+ + LLD+ L P GE++V G +
Sbjct: 1831 TETTVNCLEHRIAPDADVPSGP-VPVGRPVPGVRVLLLDDRLRPVAPGVTGELYVCGPGV 1889
Query: 318 AAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY A RF P E R+YRTGD G ++Y GR DAQVK+RG R
Sbjct: 1890 ARGYRARPAATAERFVACPQGRPGE--RMYRTGDLMRWTADGELVYEGRADAQVKVRGFR 1947
Query: 375 VDLLEVERALAQVPGV-DKCVVLCYGLD-----RGNP-------EILGFVTTKPGARTSA 421
V+ EVE AL +PGV + V L G + G P ++G+V GA
Sbjct: 1948 VEPGEVEAALLGLPGVREAAVTLLEGPEGTEGPEGAPGRVAAPARLVGYVV---GASEEP 2004
Query: 422 QHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ +LR L +M+P +++++++PL NGK+DR+ L
Sbjct: 2005 AALLERLRVRLPDHMVPAALVDLDALPLTPNGKLDRRAL 2043
Score = 37.1 bits (82), Expect = 1.8
Identities = 43/171 (25%), Positives = 71/171 (41%), Gaps = 26/171 (15%)
Query: 412 TTKPGARTSAQHIEGKLRSALTH----YMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENT 466
T P A + + + +LRS L YM+P V+ ++++PL NGKVDR L
Sbjct: 6113 TNDPTAGSHHRELAARLRSHLAERLPDYMVPSAVVVLDALPLTANGKVDRNAL------- 6165
Query: 467 NNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNS 526
D D +G LGR + ++ F+ LGG+S+ S
Sbjct: 6166 --PDPDPAGTDAGRPPRTPREELLCTLFADLLG--LGR-----VGVQDSFFGLGGDSVLS 6216
Query: 527 IYTITKLRDRGYYVEISDFL---GASTLGEVLS--KMSTDPNGGADSKEAT 572
+ +++ R G + D A+ L L + ++P+GG +AT
Sbjct: 6217 VRLVSRARAHGLPLTTRDVFEHHTAAALAAALDGREPESEPDGGPPGPDAT 6267
>UniRef50_Q2ANX0 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Bacillus weihenstephanensis KBAB4|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Bacillus weihenstephanensis KBAB4
Length = 1476
Score = 190 bits (462), Expect = 2e-46
Identities = 147/546 (26%), Positives = 259/546 (47%), Gaps = 50/546 (9%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVI--YDDSA--DPSMFKESGVP 74
TI+ +L KAGA Y+P++P +P R+ ++L+D++ +++ +D S D S++ +
Sbjct: 498 TIIGILGILKAGAVYLPIDPQYPSERVNYMLQDSDINILFTNFDISHQWDLSLYAVEVIH 557
Query: 75 F-ASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNR 133
A+ + + + EP D +A ++YTSGSTG PKG + + N
Sbjct: 558 ISAAHIYMGDTSNIKNRSEPTD-----------LAYIIYTSGSTGNPKGTMIEQKGLVNY 606
Query: 134 LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIE 193
+ W + + + E+ ++L F +V I+ PL+ G ++I + + E
Sbjct: 607 ISWANQVYVGASENEVFPLYSSLAFDLTVTTIFTPLISGNQIIIYPADANEYVLYRIFKE 666
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ + L S L L + +K + GE L+ +LA+ K G E K+ N
Sbjct: 667 KKASIIKLTPSHLFLLK--DSDFVGCSIKKIIVGGENLTVDLAANIQKKLGRET--KIYN 722
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + V + + + D ++PIG P N IY+LD +L P GE++++
Sbjct: 723 EYGPTETV--VGCMIHQFDIEKDKGVSVPIGVPAQNMKIYVLDSDLRPVPMGVVGEIYIS 780
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKG-AVLYAGRTDAQVKI 370
G +A GY RF NP++ E +++Y++GD ++G + Y GR D QVK+
Sbjct: 781 GEGVARGYFNNQDLTRERFIVNPYS---EKEQMYKSGDLARFIEGDKIEYLGRKDDQVKV 837
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L + P + + VV+ GN + + T +TS + L+
Sbjct: 838 RGFRIELKEIEINLQKYPSIKEVVVIDQEDYDGNHYLCAYYTENAKVKTS--ELFRFLKE 895
Query: 431 ALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P I ++ IPL NGK+DR+ L K + E+ D+
Sbjct: 896 ILPVYMIPSYFIVLKEIPLTFNGKLDREALPKPEVKIEKKTEGEIESDL----------- 944
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
+G + +S+R FY LGG+S+ +I +K+R++G ++ D L
Sbjct: 945 --------LGIIREVLNVEKVSIRDNFYHLGGDSIKAIQISSKIREKGIKIKTKDILANP 996
Query: 550 TLGEVL 555
+ +++
Sbjct: 997 VIEDMI 1002
>UniRef50_UPI000045BE69 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide
synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1401
Score = 189 bits (461), Expect = 2e-46
Identities = 132/450 (29%), Positives = 236/450 (52%), Gaps = 27/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+L K+GAAY+P++PS PQ R+ +L +AE ++ + ++ + V + + +
Sbjct: 604 LVAVLGILKSGAAYLPIDPSLPQERLNWLLDNAEVAIAFTQPRLEVNLSFATQVKWLTID 663
Query: 80 E--LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ L Q +TS +P+ + T + +A V+YTSGSTGIPKGV + + N +
Sbjct: 664 DSTLVQASTS----QPLPSIQ----TPEDLAYVIYTSGSTGIPKGVTIDHRGAANTILDI 715
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ER 194
+ F + + + ++L+F SV +I+G L G +++ + +RDP +++ E+
Sbjct: 716 NQRFGMTAEDRVFAI-SSLSFDLSVYDIFGTLAAGGTIIMPDAQGSRDPAHWLDVLQREQ 774
Query: 195 LVL---VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ + P L++ ++ Y A R ++L + SG+ + L + GN+ ++
Sbjct: 775 VTVWNSAPALMKLLVEY-AGDRCDRLSSSIRLVMMSGDWIPVTLPEQIHS-LGND--VQV 830
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
+ G+TE +Y +E D + +IP G+PL N +I++LDE L P D PG+++
Sbjct: 831 ISLGGATEASIWSIFYPIEAVDPS--WTSIPYGKPLSNQSIHILDEALQPRPDWVPGQIY 888
Query: 312 VAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
+ G LA GY + H E RLY TGD G L G + + GR D QVKI
Sbjct: 889 IGGVGLAQGYWRDAAKTQASFIQHPRTGE--RLYCTGDLGRYLPDGNIEFLGRIDFQVKI 946
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG+R+++ E+E L Q P + V G R + +++ ++ + ++ + L+
Sbjct: 947 RGYRIEIGEIETVLQQHPAIRSVAVSAVGEQRDDKQLVAYIVFEQEQSITSLELRSYLQQ 1006
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P + + ++S+PL NGKVDR+ L
Sbjct: 1007 KLPEYMIPSMFMFMDSLPLSSNGKVDRRAL 1036
>UniRef50_Q7N7D0 Cluster: Complete genome; segment 5/17; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 5/17 - Photorhabdus luminescens subsp.
laumondii
Length = 1060
Score = 189 bits (461), Expect = 2e-46
Identities = 173/552 (31%), Positives = 265/552 (48%), Gaps = 58/552 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA K GAAY+ + P +P R+ +++ D+ LV+ +M K+S V
Sbjct: 75 IIAMLAALKVGAAYLALPPDYPTERLRYMITDSRTRLVL-----TRTMMKDSTV------ 123
Query: 80 ELAQEATSHSAD-EPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ AT + + + + + L +TS +A V+YTSGSTG PKGV +++ + N + +
Sbjct: 124 -IENVATVYIDEIQSVVPKILPQVTSQQLAYVIYTSGSTGRPKGVGVTHHGVTNFVSQKQ 182
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILS---RETTRDPQKLVN--IE 193
+ + +E+I A F S EIWG L +G AL++ S + P+ LV I
Sbjct: 183 QYVHFGPNEKILQLAPA-AFDASAFEIWGALTNGAALVLASPSYQAIDELPKCLVEHGIT 241
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDG----Y 249
L+L P L ++ Y S P +L V G+ +S + FKY + +
Sbjct: 242 ILLLTPALFHVLVDYREEALDSVP----QLLV-GGDAMS---VTHAFKYLSRKQKLGKHF 293
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
N YG TE V+ Y + S +D + P+G+P+ N +YLLDE L P R E GE
Sbjct: 294 LFNNVYGPTEGTTLVSSYSMS-SLSIDAIKS-PLGKPIVNAEMYLLDEMLRPVRPGERGE 351
Query: 310 VWVAGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDA 366
+++ G ++A GY+ G RF +P +TQP R++ TGD G L G + + GR D
Sbjct: 352 IYIGGQSVARGYLYQPGLTSLRFLPDPFSTQPG-ARMFATGDEGVLSNDGLIEFVGRLDD 410
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDK-CVVLCYGLDRGNPEILGFVTTKPGARTS----- 420
QVK+RGHRV+L EVE A+ V CVVL DR +++ TT T
Sbjct: 411 QVKVRGHRVELAEVEHAIKSCQDVSAVCVVLNIDSDRHVEQLVAHYTTHIDHTTHKNTDV 470
Query: 421 AQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDID 479
Q I ++++ L YM P Q I+ E +PL +GKVDR+ L+ E AE ++
Sbjct: 471 EQAIITRVQTLLPSYMWPSQFIQHEQLPLTSSGKVDRRFLMGWKE-------AERLEEVV 523
Query: 480 CSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYY 539
+G + + F+ LGG+SL +I I + RG
Sbjct: 524 SGELSMTEALVAEIWQQILGPF-------DVVPDADFFALGGDSLLAIQVIAEAEKRGLN 576
Query: 540 VEISDFLGASTL 551
+ +S STL
Sbjct: 577 LTLSTLFRTSTL 588
>UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1; Myxococcus
xanthus|Rep: Saframycin Mx1 synthetase B - Myxococcus
xanthus
Length = 1770
Score = 189 bits (461), Expect = 2e-46
Identities = 137/444 (30%), Positives = 217/444 (48%), Gaps = 28/444 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA +AG AYVP++P++P+ R+ I++DAE V+ A S G E
Sbjct: 1240 VVGLLAVLEAGGAYVPLDPNYPRQRLDFIMRDAEMP-VLLTQRALASRLSPHGARLLFLE 1298
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + + P+ T AP+ + +A VLYTSGSTG PKGV +S+ + + W
Sbjct: 1299 E------PDTQEGPLP--TPAPVQPEQLAYVLYTSGSTGQPKGVAISHRSAATFVQWAGE 1350
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
TF + + T++ F SV E++ PL +G +++ +T +L + L+
Sbjct: 1351 TFSKEELTGVLA-ATSICFDLSVFELFVPLSYGGRVIL--ADTALHLLELPAASEVTLIN 1407
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
T+ +I L +R + L +GE L+ +L + + + ++ N YG +E
Sbjct: 1408 TVPSAITELLNASGIPSSVRTINL---AGEALTSDLVA---RLYAETPAARVVNLYGPSE 1461
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
TY L + IGRP+ N +Y+LD L+P GE+++ GA +A
Sbjct: 1462 TTTYSTYTPLPA----QAVEPVSIGRPVANTQVYVLDRHLAPVPVGVRGELFIGGAGVAR 1517
Query: 320 GYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRVD 376
GY+G A RF +P P R+YRTGD +G++ + GR D QVK+RG R++
Sbjct: 1518 GYLGRPRMTAERFLPDPFREAPG-ARMYRTGDIVRYRAEGSLEFLGRADHQVKVRGFRIE 1576
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
E+E AL P V + VV+ G ++ +V + + LR L YM
Sbjct: 1577 FEEIETALRNHPAVREAVVVARGTG-AERHLVAYVVLSARGESLVTELREHLRGRLPDYM 1635
Query: 437 MPQV-IEVESIPLLVNGKVDRQGL 459
+P V + +E +PL NGKVDR L
Sbjct: 1636 VPGVFVMMEVLPLTPNGKVDRAAL 1659
Score = 38.7 bits (86), Expect = 0.59
Identities = 25/73 (34%), Positives = 35/73 (47%)
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
EL+ AT A E A L+ DS+A + YTSGST PKGV L++ + + L
Sbjct: 155 ELSWVATDGIALEEAGAWKPPGLSGDSVAFLQYTSGSTADPKGVVLTHRNLMHNLSVIHE 214
Query: 140 TFPYSDSEEICVW 152
F + +W
Sbjct: 215 RFQLNRGSRGVIW 227
>UniRef50_A7IJ33 Cluster: Amino acid adenylation domain; n=1;
Xanthobacter autotrophicus Py2|Rep: Amino acid
adenylation domain - Xanthobacter sp. (strain Py2)
Length = 3208
Score = 189 bits (461), Expect = 2e-46
Identities = 169/546 (30%), Positives = 260/546 (47%), Gaps = 50/546 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I LLA K GAAY+P++P +PQ R +++ DA ++ D +A+ + ++G+ +
Sbjct: 2656 IAGLLAILKTGAAYLPLDPIYPQARRAYMIGDAGVRCILAD-TANSADLPQTGLRHIPLD 2714
Query: 80 ELAQEATSHSADEPMDAETLAPLTS-DSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ A+E A L P D A V+YTSGSTG PKGV +++ + RL+
Sbjct: 2715 LYGE------AEEDAAAMRLWPSPHPDQPAYVIYTSGSTGAPKGVVVTHGNVA-RLFTA- 2766
Query: 139 RTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---E 193
T P+ VW A F SV EI+G L G L+++ E +R P++ +++ E
Sbjct: 2767 -TAPWFGFGPDDVWTLFHAYGFDFSVWEIFGALSFGGRLVVVPHEVSRAPEEFLDLVVRE 2825
Query: 194 RLVLV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
R+ ++ P+ R L +AL P L+ + GE L + ++ FG + +
Sbjct: 2826 RVTVLNQTPSAFRPFLQ-VALARTETPDLALRHVIFGGEALDVGVLGPWYARFGIKA--R 2882
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE VTY L D L + PIG P+ + ++LLD+ L P PGE+
Sbjct: 2883 LVNMYGITETTVHVTYRPLGPGDVLGSSRS-PIGGPIPDLTLHLLDDMLDPVPVGVPGEL 2941
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQ 367
V GA LAAGY+ G A RF +P+ P RLY +GD G + Y GR D Q
Sbjct: 2942 CVGGAGLAAGYLKRPGLTAARFVPDPYG--PPGSRLYLSGDKAVRRPDGTLDYLGRGDGQ 2999
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VKIRG R++L E+E L V V+ L G P ++ +V +A + +
Sbjct: 3000 VKIRGFRIELGEIEARLRDDATVTDAAVVVRELP-GGPALVAYVVATGTVDPTA--VRER 3056
Query: 428 LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
L++ L YM+P V+ ++++PL NGK+DR L + ++ E A +
Sbjct: 3057 LQAGLPDYMVPAHVVALDALPLTANGKLDRAALPEPRATATSSAPPEGADE--------- 3107
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDF 545
+GA G + F+ LGG+SL++ ++RDR G V +
Sbjct: 3108 -EALAAIWRDVLGA-------GAIGREDNFFALGGHSLSATQVRLEIRDRLGVEVPVRRL 3159
Query: 546 LGASTL 551
TL
Sbjct: 3160 FECQTL 3165
Score = 162 bits (394), Expect = 3e-38
Identities = 163/577 (28%), Positives = 248/577 (42%), Gaps = 59/577 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I ALLA WKAG A+VP +P P RI HIL DA +LV+ + P GVP +
Sbjct: 1200 IAALLAVWKAGGAFVPFDPDHPAERIAHILADAGTTLVLAREGVTP------GVPVLDPD 1253
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ + +S A P+ S+ +A ++YTSGSTG PKGV +++ A+ + +
Sbjct: 1254 QI--DLSSQPAT-PVSRTA----HSEQLAYLVYTSGSTGRPKGVMVAHGALA--MHCRAT 1304
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWG-PLLHGRALLILSRETTRDPQKLVNIERLVLV 198
Y SE + D E W PL+HG A+++ R L + R
Sbjct: 1305 GALYETSERTREFHFLSMSFDGAHERWMVPLIHGGAIILTDRTPWAMADTLDTLARHRAT 1364
Query: 199 -----PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
P L ++ + P+ L GE + E F + L N
Sbjct: 1365 HGGFPPAYLDALAQTAQARGEAPPVDILSF---GGEAMPAE---SFARAASALKPRLLIN 1418
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + + + + +LD P PIGR + Y+LD L+ PGE++VA
Sbjct: 1419 GYGPTEAVISPLAWKVPATTRLDT-PHAPIGRAVGVRRAYVLDGALNALPVGVPGELYVA 1477
Query: 314 GANLAAGY--VGGGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKI 370
G LA GY + G A RF +P P R+YRTGD G V Y GRTD Q+K+
Sbjct: 1478 GEGLARGYQAMPGATAERFLPDPFG--PPGGRMYRTGDRAHWRADGTVEYLGRTDRQIKL 1535
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVT----TKPGARTSAQHIEG 426
RG R++ EVE AL +PGV V + + +++G+V P A + +
Sbjct: 1536 RGFRIEPGEVEAALRGLPGVGAAAVALKTVG-ASAQLVGYVVVAADAAPDAAALREALPS 1594
Query: 427 KLRSAL-----THYMMPQVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCS 481
LR AL H + +++ ++++PL NGKVD L + + +
Sbjct: 1595 TLREALGRRLPDHMVPARLVVLQALPLTPNGKVDYAALPVPERPAPTTESRPPQTEEE-- 1652
Query: 482 XXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVE 541
+ A + R G L + F+ELGG+S+ S+ + + R G +
Sbjct: 1653 -----------QMLARIWAEVLRLPNGP-DLDANFFELGGDSILSLQIVARARRAGLVLS 1700
Query: 542 ISDFLGASTLGEVLSKMSTDPNGGADSKEATFTAVPM 578
D T+ + + A EA A+P+
Sbjct: 1701 ARDLFEHQTIARLAGAARREETPAA--PEAPHGALPL 1735
Score = 50.8 bits (116), Expect = 1e-04
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 28/298 (9%)
Query: 281 IPIGRPLDNCAIYLLDEEL-SPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQP 339
+ G P D+ + +LD +P + GEV G ++A GY A AT P
Sbjct: 378 VACGAPADDHGMRILDPATGAPVPEGRVGEVVAFGPSIAQGYWNNPAATA------ATFP 431
Query: 340 EFQ--RLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERAL-AQVPGVDKCVVL 396
E + R RTGD G L G + AGR + IRG + ++E + +V V + +
Sbjct: 432 EIEGVRALRTGDLGFLSGGQLYLAGRAKDLIIIRGQNLYPHDIEEVIEREVDLVRQGRIA 491
Query: 397 CYGLDRGNPEILGF---VTTKPGARTSAQHIEGKLRSAL-THYMMPQ----VIEVESIPL 448
+ + + E +G ++ + SAQ I + + ++ P ++E ++P
Sbjct: 492 AFPVACDDGEGIGVAVEISRRTRKTVSAQSIAALVAEVVGDAFLEPARVVVLLEPGALPR 551
Query: 449 LVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAA-- 506
+GK+ R + + Y+ + DA + + A+ + A
Sbjct: 552 TSSGKLQRSAVARGYQ--DGTLDAFAILRDGVLEDRTGEIAPMTPVAPALSAMADKLAAI 609
Query: 507 ------RGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEVLSKM 558
R L+ S F+ LGGNS+ ++ +L G V +++ TLG + + +
Sbjct: 610 WSEVLGRQDLTADSHFFALGGNSVEAMRVRARLAALGLDVPVAELFRHPTLGRLAAAL 667
Score = 35.9 bits (79), Expect = 4.2
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
Query: 101 PLTSDSIAIVLYTSGSTGIPKGVRLSY-SAICNRLWWQFRTFPYSDSEEICVWKTALTFV 159
P SD IA + YTSGST PKGV +S+ + I N + + F + I W +
Sbjct: 170 PRPSD-IAFLQYTSGSTSTPKGVMVSHGNLIANEIAIR-AGFSIQPDKTILSWLPLYHDM 227
Query: 160 DSVCEIWGPLLHGRALLILS 179
+ + PL +G A +++S
Sbjct: 228 GLIGGLLQPLFNGAACILMS 247
>UniRef50_A6VVR6 Cluster: Amino acid adenylation domain; n=1;
Marinomonas sp. MWYL1|Rep: Amino acid adenylation domain
- Marinomonas sp. MWYL1
Length = 1336
Score = 189 bits (461), Expect = 2e-46
Identities = 143/446 (32%), Positives = 230/446 (51%), Gaps = 24/446 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALL T KAGAAY+P++P FP+ R+ I++DA P L++ A + K + +P +
Sbjct: 536 LVALLGTLKAGAAYLPLDPDFPEERLRGIVEDANPKLILSCHGAIGQLPKVN-MPILLID 594
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S D + T + ++ A VLYTSGSTG PKGV +S+ A+ N L +
Sbjct: 595 DSHSDI---SLDNNVSHPTNLSIQGNNPAYVLYTSGSTGRPKGVEISHKALMNFLCAMQK 651
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ SE+ + T ++F S+ E++ P+ G ++LI R+T RDPQ L ++ V
Sbjct: 652 ELDLT-SEDKFLAITTISFDISILELFLPITVGASVLIADRKTVRDPQTLTDLAVTEGVT 710
Query: 200 TLLRSILMYLALGPA-SRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L + ++ AL P S L+ ++ V GE L +LA + G+ + N YG T
Sbjct: 711 LLQATPSLWQALLPTYSNELKGIRPLV-GGEALPGQLAQ-----IMSNLGHPVVNLYGPT 764
Query: 259 EVMGDVTYYVLEGSDQLDL-YPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
E + ++ DL +P PIGRPL N +Y+LD + P G++++AG L
Sbjct: 765 ET--TIWSSIMPLVKPTDLRHP--PIGRPLLNTQMYVLDHAMEPVPVGVTGDLYIAGDGL 820
Query: 318 AAGYVGGGGA--NRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHR 374
A GY RF NP+ + RLY TGD + VL Y GR D Q+KIRG R
Sbjct: 821 ALGYYNRPELTNERFISNPYGKKG--SRLYITGDKARWRQDGVLEYQGRDDHQIKIRGFR 878
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
+++ ++E AL V + +V+ + +++ +V + + +L + L
Sbjct: 879 IEIGDIETALLACREVIQAIVVAQTSPNEDKQLVAYV-IPVDSNLDTSELRRQLINVLPD 937
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P + ++ +PL NGKVDR+ L
Sbjct: 938 YMVPAHFMLLDEMPLTPNGKVDRKAL 963
>UniRef50_A4ZPY5 Cluster: DepE; n=2; cellular organisms|Rep: DepE -
Chromobacterium violaceum
Length = 1892
Score = 189 bits (461), Expect = 2e-46
Identities = 173/578 (29%), Positives = 253/578 (43%), Gaps = 50/578 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+LA KAGA YVP++ P R+ +L D +I + A F + G
Sbjct: 540 SVVAILAVLKAGAFYVPLDLDHPSERLAWMLDDIGAGALICGEEAR-DRFGDFGGVLIGM 598
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ A A P D + V+YTSGSTG PKGV + + +
Sbjct: 599 GDAAAPGEREDAPPPRDTSPA------DLCYVIYTSGSTGQPKGVCVEHRNADHLFAATR 652
Query: 139 RTFPYSDSEEICVWKT--ALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK-LVNIER- 194
R++ S+ VW + F SV EIWG LLHG L I+ +R P + L +ER
Sbjct: 653 RSYGIGPSD---VWTLFHSYAFDFSVWEIWGALLHGGRLEIVPYRCSRTPDEFLALLERE 709
Query: 195 ----LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
L P+ + +L AL A RPL +V G + + S+F + G
Sbjct: 710 GVTMLSQTPSAFKQLLR--ALDDARRPLPAGLRYVFFGGEAT--IPSQFAACLNDAGGVA 765
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE VT VL D P+GRPL +YLLD P PGE+
Sbjct: 766 LVNLYGITETTVHVTERVLGPGDAQS--SRSPVGRPLPGYRVYLLDAAGHPVPPGVPGEI 823
Query: 311 WVAGANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQ 367
V G +A GY +R F +P +RLYR+GD G +G + Y GR D Q
Sbjct: 824 HVGGEGVARGYHNRPELDRERFIADPFLPG---ERLYRSGDLGRFDARGELDYLGRIDDQ 880
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLD-RGNPEILGFVTTKPGARTSAQHIEG 426
VKIRG R++L EVE LA+ P V V+ G+ ++ GFV + AR S +
Sbjct: 881 VKIRGFRIELGEVEATLARHPDVAAAAVMVDDATIDGHAQLAGFVVARGSARVSGSALRD 940
Query: 427 KLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXX 485
L L + +P +V+E+++IPL NGK+DR+ L +A D D +
Sbjct: 941 WLAQRLPPHAVPARVVEMDAIPLTSNGKLDRRRLA-----------GALAADADAA--RP 987
Query: 486 XXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDF 545
VG R + + F+ELGG+S+ SI ++ + D
Sbjct: 988 RIAPRNTVEQALVGVFESVLKRSPIGVTDNFFELGGDSILSIQILSAAHKVNIDFSLDDL 1047
Query: 546 LGASTLGEVLSKMSTDPNGGADSKEATFTAVPMRDEHK 583
+ + T+ + ++ A S T +A P+ H+
Sbjct: 1048 MRSLTIERLAPRVRQ-----AGSAPPTASAPPLDAVHE 1080
>UniRef50_Q9I157 Cluster: PvdL; n=23; root|Rep: PvdL - Pseudomonas
aeruginosa
Length = 4342
Score = 189 bits (460), Expect = 3e-46
Identities = 145/449 (32%), Positives = 220/449 (48%), Gaps = 27/449 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++P +P R+ ++L D+ L++ + GV +
Sbjct: 1192 LVGLLAIVKAGGAYVPLDPDYPSERLAYMLADSGVELLLTQAHLFERLPGAEGVTPICLD 1251
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + + P A L L D++A V+YTSGSTG PKGV +++A+ RL W
Sbjct: 1252 SLKLD------NWPSQAPGLH-LHGDNLAYVIYTSGSTGQPKGVGNTHAALAERLQWMQA 1304
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T+ D +++ + K ++F SV E + PL+ G L++ + RDP +LV + R V
Sbjct: 1305 TYTL-DGDDVLMQKAPVSFDVSVWECFWPLVTGCRLVLAAPGEHRDPARLVELVRQFGVT 1363
Query: 200 TL--LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL + +L P L+ GE L EL + + L N YG
Sbjct: 1364 TLHFVPPLLQLFIDEPGVAACGSLRRLFSGGEALPAELRNRVLQRL---PAVALHNRYGP 1420
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE +VT++ D PIGRPL N +LD E + GE+ + G L
Sbjct: 1421 TETAINVTHWQCRAEDG----ERSPIGRPLGNVVCRVLDAEFNLLPAGVAGELCIGGLGL 1476
Query: 318 AAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+G A RF +P + E RLYRTGD G + Y GR D QVK+RG R
Sbjct: 1477 ARGYLGRPALSAERFVADPFSAAGE--RLYRTGDRARWNADGVLEYLGRLDQQVKLRGFR 1534
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA---QHIEGKLRSA 431
++ E++ L PGV + VV+ G+ +++G+ T GA A Q + L++
Sbjct: 1535 IEPEEIQARLLAQPGVAQAVVVIREGVAGS-QLVGYYTGAVGAEAEAEQNQRLRAALQAE 1593
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P Q++ + +PL +GK+D + L
Sbjct: 1594 LPEYMVPTQLMRLAQMPLGPSGKLDTRAL 1622
Score = 147 bits (355), Expect = 2e-33
Identities = 132/468 (28%), Positives = 212/468 (45%), Gaps = 48/468 (10%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADP---SMFKESGVPFASFE 79
++ ++KAGA Y+P++P P R+T I++ + +++ + ++F E G
Sbjct: 3780 IVGSFKAGAGYLPLDPGHPTQRLTRIVELSRTLVLVCTQACREQALALFDELGCVDRP-R 3838
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + D + + ++A V+YTSGSTG+PKGV + + + N Q
Sbjct: 3839 LLVWDEIQQGEGAEHDPQVYS--GPQNLAYVIYTSGSTGLPKGVMVEQAGMLNN---QLS 3893
Query: 140 TFPY--SDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------N 191
PY D ++ + +F SV + L G + I+ DPQ L+
Sbjct: 3894 KVPYLELDENDVIAQTASQSFDISVWQFLAAPLFGARVAIVPNAVAHDPQGLLAHVGEQG 3953
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
I L VP+L++ + L + L L+ + +GE + ELA ++ K + L
Sbjct: 3954 ITVLESVPSLIQGM-----LAEERQALDGLRWMLPTGEAMPPELARQWLKRYPR---IGL 4005
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP---- 307
N YG E DV ++ ++ + Y +PIG P DN +YLL + P
Sbjct: 4006 VNAYGPAECSDDVAFFRVDLASTESTY--LPIGSPTDNNRLYLLGAGADDAFELVPLGAV 4063
Query: 308 GEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDA 366
GE+ VAG + GYVG PH +RLYRTGD G + Y GR D
Sbjct: 4064 GELCVAGTGVGRGYVGDPLRTAQAFVPHPFGAPGERLYRTGDLARRRADGVLEYVGRIDH 4123
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA----- 421
QVKIRG R++L E+E L + V + V G ++G++ R+SA
Sbjct: 4124 QVKIRGFRIELGEIEARLHERADVREAAVAVQEGANGK-YLVGYLVPGETPRSSADSPAG 4182
Query: 422 ---------QHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ I+ +LR+ L YM+P + ++ +PL NGK+DR+ L
Sbjct: 4183 LMVEQGAWFERIKQQLRADLPDYMVPLHWLVLDRMPLNANGKLDRKAL 4230
Score = 141 bits (341), Expect = 8e-32
Identities = 129/456 (28%), Positives = 213/456 (46%), Gaps = 32/456 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++P +P R+ ++++D+ L++ + ++F+ G A
Sbjct: 2250 VVGLLAILKAGGAYVPLDPEYPLERLQYMIEDSGVRLLL----SHAALFEALGELPAGVA 2305
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + D A A A ++YTSGSTG PKGV +S+ I
Sbjct: 2306 RWCLEEDGPALDAEDPAPLAALSGPQHQAYLIYTSGSTGKPKGVAVSHGEIAMHCAAVIE 2365
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRET--TRDPQKLVNIERLVL 197
F +E+ + ++ F + + PLL G +++ ++ + +L+ E + +
Sbjct: 2366 CFGMR-AEDCELHFYSINFDAASERLLAPLLCGARVVLRAQGQWGAEEICELIRAEGVSI 2424
Query: 198 V---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ P+ + +L P+R + + GE L+ E + F + N
Sbjct: 2425 LGFTPSYGSQLAQWLESQGRQLPVR---MCITGGEALTGEHLQRIRQAFAPASFF---NA 2478
Query: 255 YGSTEVMGDVTYYVLEGSDQLDL-YPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + V ++L+ ++PIG + Y+LD +L+ GE++V
Sbjct: 2479 YGPTETV--VMPLACLAPERLEEGAASVPIGSVVGARVAYILDADLALVPQGATGELYVG 2536
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKI 370
GA LA GY A RF +P A E RLYRTGD L G V Y GR D QVKI
Sbjct: 2537 GAGLARGYHERPALSAERFVPDPFAA--EGGRLYRTGDLVRLCDNGQVEYVGRIDHQVKI 2594
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTT------KPGARTSAQHI 424
RG R++L E+E L + P V + +VL G ++ G+V + + + +
Sbjct: 2595 RGFRIELGEIEARLLEHPQVREALVLALDSPSGK-QLAGYVASAVAEQDEDAQAALREAL 2653
Query: 425 EGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L+ L YM+P ++ + S+PL NGK+DR+ L
Sbjct: 2654 KTHLKQQLPDYMVPAHLLLLASLPLTANGKLDRRAL 2689
Score = 54.8 bits (126), Expect = 8e-06
Identities = 63/280 (22%), Positives = 114/280 (40%), Gaps = 18/280 (6%)
Query: 284 GRPLDNCAIYLLDEELSPTR-DSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQ 342
GR A+ ++D D GE+W AG ++A GY N + + +
Sbjct: 372 GRSQPEHAVLIVDAASGEVLGDDNVGEIWAAGPSIAHGY----WRNPEASAKAFVERDGR 427
Query: 343 RLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERAL-AQVPGVDKCVVLCYGLD 401
RTGD G L G + GR + +RGH + ++ER + ++VP K V + +
Sbjct: 428 TWLRTGDLGFLRDGELFVTGRLKDMLIVRGHNLYPQDIERTVESEVPSARKGRVAAFAVT 487
Query: 402 RGNPEILGFVT-TKPGARTS--AQHIEGKLRSAL--THYMMPQVIEV---ESIPLLVNGK 453
E +G G + S AQ + +R A+ + P+V+ + ++P +GK
Sbjct: 488 VDGEEGIGIAAEIGRGVQKSVPAQELIDSIRQAVAEAYQEAPKVVALLNPGALPKTSSGK 547
Query: 454 VDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAV-LGRAARGTLSL 512
+ R E+ + D + + + +G + R ++
Sbjct: 548 LQRSACRLRLED-GSLDSYALFPGLQ-AVQEAQPPAGDDELLARIGEIWKARLGVAQVAP 605
Query: 513 RSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTL 551
R F+ LGGNS+ + + ++RD G +++ A TL
Sbjct: 606 RDHFFLLGGNSIGAAQVVAQVRDSLGVALDLRQLFEAPTL 645
Score = 43.6 bits (98), Expect = 0.021
Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 7/141 (4%)
Query: 42 QGRITHILKDAEPSLVIYD-DSADPSMFKESGVPFASFEEL-AQEATSHSADEPMDAETL 99
Q R+ I+ DAEP LV+ D +P + + + A+ +L + + E D +
Sbjct: 105 QERLLSIIADAEPRLVLTTADLREPLLQMNAQLSAANAPQLLCVDQLDPAVAEAWDEPQV 164
Query: 100 APLTSDSIAIVLYTSGSTGIPKGVRLSY-SAICNRLWWQFRTFPYSDSEEICVWKTALTF 158
P + IA + YTSGST +PKGV++S+ + + N + + R F + I W
Sbjct: 165 RP---EHIAFLQYTSGSTALPKGVQVSHGNLVANEVLIR-RGFGIGADDVIVSWLPLYHD 220
Query: 159 VDSVCEIWGPLLHGRALLILS 179
+ + + P+ G +++S
Sbjct: 221 MGLIGGLLQPIFSGVPCVLMS 241
>UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibiotic
biosynthesis; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to proteins involved in antibiotic
biosynthesis - Photorhabdus luminescens subsp. laumondii
Length = 3270
Score = 189 bits (460), Expect = 3e-46
Identities = 141/446 (31%), Positives = 220/446 (49%), Gaps = 24/446 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I ALLA KAGAAYVP++PSFP R+ ++L DAEP +I + + V FA
Sbjct: 597 ITALLAVMKAGAAYVPVDPSFPVDRVQYMLNDAEPQCIISNRE-----YASRSVGFAELT 651
Query: 80 ELAQEA-TSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L S S + +++ L + ++A V+YTSGSTG PKGV +S+SA+ N L
Sbjct: 652 CLLDHIDLSQSPTTNIPKQSIG-LAASALAYVIYTSGSTGKPKGVMVSHSAVNNFLISMQ 710
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+ I T ++F +V E++ P L G ++ +++ DP +LV + +
Sbjct: 711 DNLQCVAQDNILA-ITTISFDIAVLELYLPWLSGATCVVAAQQDVTDPARLVALLEQHSI 769
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L + + L + R + GE L A+ G L N YG T
Sbjct: 770 SLLQATPTTWNMLLESGWQGRSSLKMISGGEALPLATATALL-----SKGSALWNMYGPT 824
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E V + + QL + IG PL+N IYLLDE+L P GE+++ G LA
Sbjct: 825 ET--TVWSTIAKLDVQLLEQQLVTIGLPLNNTTIYLLDEQLKPVPFGAVGELYIGGDGLA 882
Query: 319 AGYVGGGG-ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY N + ++Y+TGD +G+++Y GR D QVK+RGHR++
Sbjct: 883 EGYFKREDLTTERLINLTFSDGLTAKVYKTGDLARYTTEGSLVYLGRNDYQVKLRGHRIE 942
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA--QHIEGKLRSALTH 434
L E+E+ + P + + VV+ + + G+V + A QH+E KL +
Sbjct: 943 LGEIEQVINLFPQITRSVVVALNDQQTQQYLAGYVVAEQQIDIDALRQHLEQKLPA---- 998
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGL 459
YM+P+ +I++E++PL +N K+DR+ L
Sbjct: 999 YMLPRAIIQLETLPLTLNNKIDRKAL 1024
Score = 182 bits (444), Expect = 2e-44
Identities = 159/533 (29%), Positives = 261/533 (48%), Gaps = 46/533 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++++LA K+G+AY+P++P++PQ R+ +I+ DA+P +VI +S + + E+ + S +
Sbjct: 1654 VVSVLAILKSGSAYLPLDPAYPQERLAYIIDDAQPLMVI-TNSHNQKLLPENSL--FSID 1710
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
S D + A L L S +A VLYTSGSTG+PKGV + + A+ N +
Sbjct: 1711 VTTTSFAELSTDN-IPAVELG-LCSTHLAYVLYTSGSTGMPKGVMIEHQALVNLVVGLAD 1768
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP----QKLVNIE-R 194
+ YS + + + AL+F S+ EI+G L +G L++ + D Q+ +
Sbjct: 1769 AYLYSKQDRVLQF-AALSFDMSIEEIFGALGNGSTLVLRGEDWLMDIATFWQRCREYQIS 1827
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
V +PT ++ +R++ + GE + + +++ G+ +L N
Sbjct: 1828 AVNLPTTFWHEVVSEETVLVPEHIRQISV---GGEQIKPDKVVAWYQRPGHLP--RLVNA 1882
Query: 255 YGSTE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + Y L G T+ IG P+ N AI+LLD+ GE+ VA
Sbjct: 1883 YGPTEYTVNTCIAYDLRGD-------TLSIGHPIQNTAIFLLDKNQQLVPFGAVGEICVA 1935
Query: 314 GANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G +A GY+ R F DNP ++ + +LYRTGD G + G + Y GR D QVKI
Sbjct: 1936 GDGVARGYINKEQLTRERFIDNPFVSR--YPKLYRTGDLGRYSLAGDIQYYGRDDHQVKI 1993
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E L +P + VV+ + + + ++T G + A+ I L
Sbjct: 1994 RGFRIELGEIETRLRSLPTIRDAVVIAREDEPAHKYLAAYITL-DGQQKVAE-IRHLLSQ 2051
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P + +E IPL N KVDR+ L K D + +I+
Sbjct: 2052 QLPSYMVPAAFVVLEEIPLTANRKVDRKALPK--------PDFVIQGEIEYIAPATEQET 2103
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEI 542
T + G A +S + F+ELGG+SL S+ ++ L+ +GY ++I
Sbjct: 2104 LLAEIWRT---LFGLA---QVSAVANFFELGGHSLLSMKMLSHLKKQGYRLDI 2150
Score = 154 bits (374), Expect = 8e-36
Identities = 132/453 (29%), Positives = 214/453 (47%), Gaps = 25/453 (5%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ ++A K GA YVP++ S P R+ IL D +++ + + + V
Sbjct: 2723 FEMVITIIAILKTGAGYVPLDTSLPTERLNIILSDLSDEILVTTCALNDRI----AVKRQ 2778
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
L T+ + + + + D++ VLYTSGSTG PK + + A+ N L
Sbjct: 2779 KMVLLDDPCTAEILGKQLISNLAIESSLDNLGYVLYTSGSTGKPKAIEMPQRALSNLLQG 2838
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IERL 195
+ P + +++ F S +I+ PLL G ++ ++ + T D + L I++
Sbjct: 2839 ISQLEPALTGPNRWLQFSSIGFDLSFEDIFMPLLSGGSVQLIDKSTQLDIRLLAKQIQQA 2898
Query: 196 VL-VPTLLRSILMYLA--LGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L V L ++L LA G L++ V S E L ++ + ++F KL
Sbjct: 2899 QLQVLNLPYAVLQNLAEYSGVNGLQFPELRVIVSSAERL--KITAAIRQFFTTHRHCKLV 2956
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIP-IGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG E VT L+G +P +P IGR L N A Y+LDE L P GE++
Sbjct: 2957 NHYGPAETHV-VTSKTLQGEPAS--WPDLPTIGRSLPNVAGYILDEYLQPVPMGAIGELY 3013
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQV 368
+AG L+ GY A R+ D +R+YRTGD + + G + Y GR D V
Sbjct: 3014 LAGDCLSRGYYQQPQLTAERYLDCDWVLG---KRVYRTGDLASFHQNGEINYFGRNDHLV 3070
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILG-FVTTKPGARTSAQHIEGK 427
KIRG R++L ++E L++ G+ VV+ + G+ +++ F+ P I+
Sbjct: 3071 KIRGFRIELGDIEAQLSKFDGITGTVVIAIDTEAGDKQLIAYFIAANP---LDLSEIKTY 3127
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L ++L YM+P + + + PL NGKVDR L
Sbjct: 3128 LSASLPDYMLPSAYVRMAAFPLNTNGKVDRSRL 3160
>UniRef50_Q6N4J8 Cluster: Possible McyE polykeitde synthase and
peptide synthetase; n=1; Rhodopseudomonas palustris|Rep:
Possible McyE polykeitde synthase and peptide synthetase
- Rhodopseudomonas palustris
Length = 2682
Score = 189 bits (460), Expect = 3e-46
Identities = 146/448 (32%), Positives = 216/448 (48%), Gaps = 29/448 (6%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+AL+A KAG AYVP++PS P RI + + AE ++ I AD + E GVP E
Sbjct: 2134 VALVAVAKAGLAYVPVDPSLPVVRIRQMAEAAEVAVFI-TSGADCPVAAEMGVPVIDLER 2192
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
A + + S+ P A L DS A V++TSGSTG PKGV +S+ A+ N L
Sbjct: 2193 DAAQIDAASSARPEPAPPQEVL--DSTAYVIFTSGSTGTPKGVEISHRALANFLG-SMAV 2249
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER------ 194
P +++ V T ++F +V E+ PL G +I ++ +P +V + +
Sbjct: 2250 RPGFGADDRIVAVTTVSFDIAVLELLLPLYCGGRTVICGKDRLLEPDSIVRLIKTSSATI 2309
Query: 195 LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ PTL R +L+ L P SRPLR L GE L +++A + G++L N
Sbjct: 2310 VQATPTLWR-VLLEAGLQP-SRPLRALS----GGEALPRDVAEKLIAA-----GFELWNM 2358
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE T + G +D I IG P+ N +Y+L ++ + PGE+ + G
Sbjct: 2359 YGPTET----TIWSACGRI-VDASRPIVIGEPVANTDLYILSDDGTQAPVGTPGELCIGG 2413
Query: 315 ANLAAGYVGGGGANRFCDNPHATQP-EFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
LA GYV + Q RLYRTGD L G + GR D QVKIRG
Sbjct: 2414 LGLAKGYVNRPDLTAAAFPVTSLQDGRTVRLYRTGDLAVRLSDGGIQLLGRRDQQVKIRG 2473
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+E L P + V+ + ++ KPG S ++ + +L
Sbjct: 2474 FRIELEEIESVLRTCPDIVDAAVMVENAGTADAALVAAFVAKPGMAVSIDSLQQTAQLSL 2533
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGL 459
HYM+P + + V +P NGK+DR+ L
Sbjct: 2534 PHYMVPNRFVAVAELPKTANGKLDRKAL 2561
>UniRef50_Q5J1Q7 Cluster: NocA; n=1; Nocardia uniformis subsp.
tsuyamanensis|Rep: NocA - Nocardia uniformis subsp.
tsuyamanensis
Length = 3692
Score = 189 bits (460), Expect = 3e-46
Identities = 172/550 (31%), Positives = 246/550 (44%), Gaps = 53/550 (9%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELA 82
+L WKAG AYVP++P+ P R IL D P V+ D D +F ++ P + +L
Sbjct: 2309 VLGIWKAGGAYVPLDPAQPAERHRRILADCRPRAVVAD--RDDPVFGDT--PLLTVADLR 2364
Query: 83 QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFP 142
A + + P D +A V YTSGSTG PKGV+ ++ + N+L W R +P
Sbjct: 2365 PGAPA----------PVRPPEPDRLAYVAYTSGSTGEPKGVQCAHHGLANQLMWSRRAYP 2414
Query: 143 YSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIERLV--- 196
+ E + A+ F S+ E+ PL G L++L +E D +LV ER+V
Sbjct: 2415 LNPGEAL-AQVAAVGFDISLWELLHPLTSGGRLVVLDQERHGDVVAIAELVAAERVVVLH 2473
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
LVPTLL YL GPA LR + VC GE LS L + F L + YG
Sbjct: 2474 LVPTLLEH---YLDEGPAD-SLRHV---VCGGERLSPGLPAR----FAARTPAALNHTYG 2522
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE VT++ D + +G PL +YLLD P GE+ + G
Sbjct: 2523 PTEASIIVTHW--RSPDPAP--DAVSLGAPLPGARVYLLDPHGQPVPVGVVGELVLGGEV 2578
Query: 317 LAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
LA GY+G G A RF +P + P R YRTGD G + + GR D QVKI G
Sbjct: 2579 LARGYLGRPGATAERFLPDPFSDVPG-ARAYRTGDLARHRPDGGLEFVGRADRQVKILGV 2637
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ---HIEGKLRS 430
RV+ EVE AL P V C VL RG ++G++ Q + LR
Sbjct: 2638 RVEPHEVETALVANPAVAACAVLPREDARGAVGLVGYLVPADRDADPGQLRAEVGRALRE 2697
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L M+P +++ +E++P+ GK+D L + E +
Sbjct: 2698 RLPRAMVPSRLVVLEALPVGPTGKLDVGAL---------PEPDEAPAPLPAPSPTGPGTA 2748
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAS 549
VL + + F+ELGG+S+++I + + R G VE+ L A
Sbjct: 2749 AERDLAAIWAQVLPVPGDRVIGPQDNFFELGGDSVSAIRVVARARAAGLRVELGRVLRAG 2808
Query: 550 TLGEVLSKMS 559
+L E+ + S
Sbjct: 2809 SLAELAASAS 2818
Score = 173 bits (420), Expect = 2e-41
Identities = 163/555 (29%), Positives = 248/555 (44%), Gaps = 55/555 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ALL AG A++P+ P P RIT L LVI +AD F FA
Sbjct: 1197 VAALLGVLAAGRAFLPLSPEDPDDRITRQLDLGGARLVI---AADADRFAADR--FAGVT 1251
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ + A E A PL D+ A V++TSGSTG PKGV + + A+ + + W
Sbjct: 1252 AVSPLVPAEGAGEAPLAPLPEPLPGDA-AYVIFTSGSTGEPKGVVVEHRALADHVRWAVG 1310
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ + + + A+ F V E+ L G A+++ E+ Q LV + R V
Sbjct: 1311 EYGLTAGDRALQF-CAVAFDVLVEEVLPTLASGAAVVLRDEESATSAQALVELCAARGVT 1369
Query: 198 VPTLL-----RSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
V L R + + G A P ++L V G+ + + + + + +L
Sbjct: 1370 VANLPTGYWERLVAAFDEDGTALPP--SVRLVVIGGQQVDRSAVERWHRL---PNPVRLV 1424
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPT--IPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
N YG TE+ G+ DL P +PIG P +N YLLD L+P D E+
Sbjct: 1425 NAYGPTEMT--------IGATAADLVPGGGVPIGGPTENTRAYLLDRYLAPVPDGVVAEL 1476
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYAGRTDAQV 368
++AG+ LA GY G RF +P A QR+YRTGD GA+ + GR D QV
Sbjct: 1477 YLAGSGLARGYSRRPGLTGERFLPDPFAGGG--QRMYRTGDLAVRRDGALHFIGRVDRQV 1534
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RGHR++L EVE AL PGV + VL G ++ V P + L
Sbjct: 1535 KVRGHRIELDEVESALTAAPGVAEAAVLLRG-----GRLVAHVAAPP--EVDGAGLRAHL 1587
Query: 429 RSALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
L +M+P V+ V ++P GKVDR L ++ A++A+ D
Sbjct: 1588 AGRLPAFMVPSVVVVSRALPRTSTGKVDRNAL-----TAEPDEPADLALPGDDEPGDERE 1642
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGY-YVEISDFL 546
+G AR + +R F++LGG+SL ++ + ++ +GY + + D
Sbjct: 1643 RATSALWAQVLG-----VAR--VGVRDSFFDLGGHSLLAMDLVRRMHGQGYRRLRVPDLF 1695
Query: 547 GASTLGEVLSKMSTD 561
T+ E L+ + D
Sbjct: 1696 EHPTI-EALAPWADD 1709
Score = 153 bits (371), Expect = 2e-35
Identities = 135/471 (28%), Positives = 211/471 (44%), Gaps = 40/471 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSM----FKESGVPF 75
++A LA ++AG Y+P++P++P GR +L DA P+ V+ + D + +G P
Sbjct: 82 VVACLAVFRAGGVYLPVDPAWPAGRRAAVLADAGPAAVVVGGALDGGVAGAGALHAGAPG 141
Query: 76 ASFEE--LAQEA----TSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSA 129
A + LA EA DE + D A ++YTSGSTG PKGV +++ A
Sbjct: 142 AGSTDAVLAAEAPVLPVHVGDDEGAEGVPWPEPERDQAAYLVYTSGSTGRPKGVLVTHGA 201
Query: 130 ICNR-LWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILS---RETTRD 185
+ NR LWWQ P +++ + + F +V E+ + G L+I R
Sbjct: 202 LANRMLWWQ-GEHPLG-PDDVLMATASPAFDIAVWELLAAFVGGARLVIAEHRLRGVVPH 259
Query: 186 PQKLVNIERLVL---VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKY 242
+L+ R+ + VP++L +L ++A G L+L VC GE +
Sbjct: 260 LPELMTDHRVTVAHFVPSVLEELLGWMADGGRV----GLRLVVCGGEAVPPSQRDRLLAL 315
Query: 243 FGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPT 302
G ++ + YG TE V + D P +P+GRP+ N A+ ++D +
Sbjct: 316 ----SGARMVHAYGPTETTITVVHDECRADDPA---PGLPLGRPMHNAAVAVVDADGRRA 368
Query: 303 RDSEPGEVWVAGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVL 359
GE+ V G LA GY+G G A RF + P R+YRTGD L G +
Sbjct: 369 PVGVAGELVVGGVPLARGYLGRPGETAARFVPDWLGLGPAGGRVYRTGDRARRLPDGRIE 428
Query: 360 YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART 419
+ GR D + K+RGHRVD E+E L Q P V + V ++ ++
Sbjct: 429 FLGRVDDEFKVRGHRVDPAEIESLLHQHPLVGRAAVRL----ADGAHVVAYLQGSADPAE 484
Query: 420 SAQHIEGKLRSALTHYMMPQVIEVESIPLLVNGKVDRQGLLKMYENTNNND 470
H+ +L A+ + + + ++ PL NGKVD L N D
Sbjct: 485 LRAHLADRLPLAV---IPTRWVRLDRFPLTPNGKVDYAALPAAPARANGQD 532
>UniRef50_A6YEH2 Cluster: CmnA; n=1; Saccharothrix mutabilis subsp.
capreolus|Rep: CmnA - Streptomyces capreolus
Length = 2401
Score = 189 bits (460), Expect = 3e-46
Identities = 150/452 (33%), Positives = 224/452 (49%), Gaps = 33/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAG A+VP++P +P+ R+ H+L D+ ++V+ F G P +
Sbjct: 425 VVALLAVLKAGGAFVPLDPQYPRQRLAHMLADSGAAVVLTQGRL-RDRFAADGPPVLVTD 483
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A H + P A D +A V+YTSGSTG PKGV + + I + L
Sbjct: 484 DDATRFAHHPSSAPP-----ASSGPDDLAYVVYTSGSTGRPKGVMVEHRGIASYLRGMQH 538
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN-IER---- 194
FP + + + + T+L+F SV EI+ PL G A+++ + DP L I+R
Sbjct: 539 DFPLTPEDRV-LQATSLSFDVSVYEIFWPLQVGAAVVLPAPGGHTDPYHLSELIQRHGVT 597
Query: 195 -LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP+L+R + G A LRR+ SGE L L + + E L N
Sbjct: 598 CLHFVPSLMRLFVEEADPG-AGAGLRRV---FVSGEALDPSLVALVHERTSAE----LVN 649
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG+TEV D TY+ +D+ + +GRP+ N Y+LD+ L P GEV++
Sbjct: 650 LYGATEVSVDSTYWT---ADRAKPDRPVLVGRPMANATAYVLDQRLRPKPAGVVGEVFLG 706
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKI 370
GA++ GY A RF +P P RLYRTGD G + G + + GR D Q K+
Sbjct: 707 GASVTRGYHARPALTAERFVPDPFG--PPGSRLYRTGDLGRVTPDGELEFLGRRDHQFKL 764
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG RV+ E+E A+ PGV+ VV+ G + +L +V G +A + L
Sbjct: 765 RGWRVEAGEIEAAITAHPGVNGAVVVTEGAHE-HATLLAYVGADAGLDQAA--LREFLAR 821
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLK 461
L ++P + I ++ +P+ NGKVDR L K
Sbjct: 822 RLPRPLVPARFIRLDRLPISPNGKVDRAALPK 853
Score = 169 bits (410), Expect = 3e-40
Identities = 140/448 (31%), Positives = 215/448 (47%), Gaps = 38/448 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+ KAG AYVP+E S P RI ++ D+ +LV+ + E
Sbjct: 1470 LIAVYGVLKAGGAYVPVETSNPDLRIAELIADSGAALVLTQRRLADRLAALGAEVVVVDE 1529
Query: 80 ELAQEATSHSADEPMDAETLAPLTS-DSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L + T+ D E PLT D +A V+YTSGSTG PKGV + + ++ N L
Sbjct: 1530 PLPRHPTT-------DPE---PLTGPDHLAYVIYTSGSTGRPKGVMVQHGSVLNFLDALD 1579
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERL 195
R F + + + + K+ L F SV E++ L G ++++ DP LV++ ER+
Sbjct: 1580 RRFDLTPDDRL-LHKSPLAFDVSVREVFWALTRGASVVVAEPGRHADPGHLVDLVERERV 1638
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + S+ ++L P L+ + SGETL A G +L N Y
Sbjct: 1639 TVAHFVPSSLAVFLEGLPGPGRCPTLRHVLTSGETLPVTTARAARDLL----GARLRNMY 1694
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE ++T + + D +D +PIG P + + +LD +L P GE+ V G
Sbjct: 1695 GPTETTVEMTDHDVV-DDTVD---RLPIGHPFEGAVVRVLDADLRPVPPGSTGELCVGGL 1750
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRG 372
+A GY+G A RF +P P RLYRTGD L+ G + + GR D QVK+RG
Sbjct: 1751 PVARGYLGRPALTAERFVPDP--LGPAGARLYRTGDLARLLPDGQLDFLGRNDFQVKVRG 1808
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
HR++ EVE L +PGV +V + DR ++G+ T + + L L
Sbjct: 1809 HRIEPGEVEAVLGALPGVHGALVTAHD-DR----LIGYAVTD----RDGEELRTALAERL 1859
Query: 433 THYMMPQVI-EVESIPLLVNGKVDRQGL 459
+++P V+ ++ PL NGK+DR L
Sbjct: 1860 PEHLVPSVVLTLDRFPLTGNGKLDRAAL 1887
>UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine
synthetase II) [Includes: ATP- dependent proline
adenylase (ProA) (Proline activase); ATP-dependent
phenylalanine adenylase (PheA) (Phenylalanine activase);
ATP-dependent D-phenylalanine adenylase (D-PheA)
(D-phenylalanine activase); Phenylalanine racemase
[ATP-hydrolyzing] (EC 5.1.1.11)]; n=5;
Paenibacillaceae|Rep: Tyrocidine synthetase 2 (Tyrocidine
synthetase II) [Includes: ATP- dependent proline
adenylase (ProA) (Proline activase); ATP-dependent
phenylalanine adenylase (PheA) (Phenylalanine activase);
ATP-dependent D-phenylalanine adenylase (D-PheA)
(D-phenylalanine activase); Phenylalanine racemase
[ATP-hydrolyzing] (EC 5.1.1.11)] - Brevibacillus
parabrevis
Length = 3587
Score = 189 bits (460), Expect = 3e-46
Identities = 155/538 (28%), Positives = 251/538 (46%), Gaps = 44/538 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LAT KAG A++P++P +P+ RI ++L+D++ LV+ + +S V +
Sbjct: 2608 VIATLATLKAGGAFLPVDPDYPEERIRYMLEDSQAKLVVTHAHLLHKVSSQSEV--VDVD 2665
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ AT D A SD +A ++YTSG+TG PKGV L + + N L F
Sbjct: 2666 DPGSYATQ------TDNLPCANTPSD-LAYIIYTSGTTGKPKGVMLEHKGVAN-LQAVFA 2717
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
++ +++F SV +++GPLL G L +LSR+ D Q+ R +
Sbjct: 2718 HHLGVTPQDRAGHFASISFDASVWDMFGPLLSGATLYVLSRDVINDFQRFAEYVRDNAIT 2777
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L + L P P L+ + +G S L ++ ++ N YG TE
Sbjct: 2778 FLTLPPTYAIYLEPEQVP--SLRTLITAGSASSVALVDKW------KEKVTYVNGYGPTE 2829
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
T + + + ++ TI IG+P+ N +Y++D++L + GE+ ++G +LA
Sbjct: 2830 STVCATLWKAKPDEPVE---TITIGKPIQNTKLYIVDDQLQLKAPGQMGELCISGLSLAR 2886
Query: 320 GYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY A +F DNP ++YRTGD L G + Y GR D QVKIRGHRV+
Sbjct: 2887 GYWNRPELTAEKFVDNPFVPG---TKMYRTGDLARWLPDGTIEYLGRIDHQVKIRGHRVE 2943
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L EVE L + V + + + DRG + + + G T AQ + + + L +YM
Sbjct: 2944 LGEVESVLLRYDTVKEAAAITHEDDRGQAYLCAYYVAE-GEATPAQ-LRAYMENELPNYM 3001
Query: 437 MPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXX 495
+P I++E +PL N K+DR+ L K + N +
Sbjct: 3002 VPAFFIQLEKMPLTPNDKIDRKALPKPNQEENRTEQ-----------YAAPQTELEQLLA 3050
Query: 496 XTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
VLG GT + F+ELGG+S+ +I T+L G+ + + + T+ E
Sbjct: 3051 GIWADVLGIKQVGT---QDNFFELGGDSIKAIQVSTRLNASGWTLAMKELFQYPTIEE 3105
Score = 168 bits (408), Expect = 6e-40
Identities = 136/452 (30%), Positives = 221/452 (48%), Gaps = 33/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +L KAG A+VP++P P RI ++L + LV+ + + + +
Sbjct: 531 IVGILGVLKAGGAFVPIDPELPAERIAYMLTHSRVPLVVTQNHLRAKVTTPTETIDINTA 590
Query: 80 ELAQEATS--HSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ +E+ + S ++P D + ++YTSG+TG PKGV L + + N + +
Sbjct: 591 VIGEESRAPIESLNQPHD-----------LFYIIYTSGTTGQPKGVMLEHRNMANLMHFT 639
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERL 195
F + E++ + T +F EI+ LL G L +++ E R +KL E+
Sbjct: 640 FDQTNIAFHEKVLQYTTC-SFDVCYQEIFSTLLSGGQLYLITNELRRHVEKLFAFIQEKQ 698
Query: 196 VLVPTLLRSILMYL--ALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ + +L S L ++ A R +K + +GE L + E KY + L N
Sbjct: 699 ISILSLPVSFLKFIFNEQDYAQSFPRCVKHIITAGEQLV--VTHELQKYLRQHRVF-LHN 755
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG +E VT ++ + P PIG+P+ N IY+LDE L + GE++++
Sbjct: 756 HYGPSETHV-VTTCTMDPGQAIPELP--PIGKPISNTGIYILDEGLQLKPEGIVGELYIS 812
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GAN+ GY+ A +F DNP+ QP +R+YRTGD L G + + GR D QVKI
Sbjct: 813 GANVGRGYLHQPELTAEKFLDNPY--QPG-ERMYRTGDLALWLPDGQLEFLGRIDHQVKI 869
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RGHR++L E+E L P + + VV+ + G + +V + S + + L
Sbjct: 870 RGHRIELGEIESRLLNHPAIKEAVVIDRADETGGKFLCAYVVLQKA--LSDEEMRAYLAQ 927
Query: 431 ALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLK 461
AL YM+P + +E IP+ NGK DR+ L K
Sbjct: 928 ALPEYMIPSFFVTLERIPVTPNGKTDRRALPK 959
Score = 161 bits (392), Expect = 5e-38
Identities = 134/453 (29%), Positives = 217/453 (47%), Gaps = 42/453 (9%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ ++A KAG AYVP++P +P RI ++L+D ++ A+ A+ E
Sbjct: 1572 IGIIAILKAGGAYVPIDPDYPNERIAYMLEDCRRLVLTQQQLAEKMT--------ANVEC 1623
Query: 81 L-AQEATSHSADEPMDAETLAPL-TSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L E S+S E + P+ T+ +A ++YTSG+TG PKGV + + I N + W
Sbjct: 1624 LYLDEEGSYSPQ----TENIEPIHTAADLAYIIYTSGTTGRPKGVMVEHRGIVNSVTWNR 1679
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI------ 192
F S + + + F + ++ G ++++ +DP L N+
Sbjct: 1680 DEFALSVRDSGTL-SLSFAFDAFALTFFTLIVSGSTVVLMPDHEAKDPIALRNLIAAWEC 1738
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+V VP++ ++IL PA +R ++ + GE LS +L + K + +
Sbjct: 1739 SYVVFVPSMFQAILECST--PAD--IRSIQAVMLGGEKLSPKLV-QLCKAMHPQ--MSVM 1791
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE TY DQ I IGRP+ N AIY++D+ GE+ +
Sbjct: 1792 NAYGPTESSVMATYLRDTQPDQ-----PITIGRPIANTAIYIVDQHHQLLPVGVVGEICI 1846
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
G LA GY A +F NP +R+Y+TGD G L G + + GR D Q+K
Sbjct: 1847 GGHGLARGYWKKPELTAEKFVANPAVPG---ERMYKTGDLGRWLHDGTIDFIGRVDDQIK 1903
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR 429
+RG+R+++ E+E L ++ +V+ Y DRG+ + +VT K S + L
Sbjct: 1904 VRGYRIEVGEIEAVLLAYDQTNEAIVVAYQDDRGDSYLAAYVTGKTAIEES--ELRAHLL 1961
Query: 430 SALTHYMMP-QVIEVESIPLLVNGKVDRQGLLK 461
L YM+P +I++++ PL NGKVDR+ L K
Sbjct: 1962 RELPAYMVPTYLIQLDAFPLTPNGKVDRKALPK 1994
>UniRef50_Q2SHZ1 Cluster: Non-ribosomal peptide synthetase modules and
related protein; n=1; Hahella chejuensis KCTC 2396|Rep:
Non-ribosomal peptide synthetase modules and related
protein - Hahella chejuensis (strain KCTC 2396)
Length = 1630
Score = 188 bits (459), Expect = 4e-46
Identities = 155/546 (28%), Positives = 254/546 (46%), Gaps = 36/546 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSA-DPSMFKESGVPFASF 78
I+ +L K+GA Y+PM+ + P+ R+ H + DA +L++ D + DP+ + + P+ +
Sbjct: 630 IVGILGILKSGAGYMPMDIAHPRARLQHQINDARLTLIVVDQATLDPA--RSAVAPYPAE 687
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
++A + P A +A + +A V+YTSGSTG PKG + + + N L
Sbjct: 688 LVCIEQALAKPVAAP--AAAIA-IQRSQLAYVIYTSGSTGAPKGSLVEHHNVLN-LVEGL 743
Query: 139 RTFPYSDSEE-ICVWKTALTFVD-SVCEIWGPLLHGRALLILSRETTRDPQKLVN--IER 194
R Y D +E +CV A D SV +I+ LL G LL+ + E P +L ++
Sbjct: 744 RDLVYQDYQEPVCVALLASPIFDASVQQIFAALLLGHQLLVAAPEMRLQPTQLAQCFLQH 803
Query: 195 LVLVPTLLRSIL-MYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V V S+L M +A + P L + GE LS++LA F++ Y N
Sbjct: 804 KVAVADCTPSLLSMMVAERLPATPGLGLDALLTGGEPLSRKLAQAFYQQNARAALY---N 860
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE DVT + + +P +PIGRPL N +++LD P PG++++
Sbjct: 861 VYGPTECAVDVTALRVPRKNPY-YFPIVPIGRPLPNAQVFILDTLRRPVPLGVPGQIFIG 919
Query: 314 GANLAAGYVGGGGANRFCDNPHATQPEF--QRLYRTGDFGTLVK-GAVLYAGRTDAQVKI 370
G + GY+ R A PE +RLY TGD G ++ G + Y GR D Q+KI
Sbjct: 920 GDPVGRGYLNRSALTR---EKFAYYPEISKRRLYATGDCGRWLRDGVIQYLGRMDQQIKI 976
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGART-SAQHIEGKLR 429
RGHRV+ E+E L Q P + + + + G E+ ++T A+ + + L+
Sbjct: 977 RGHRVEPGEIESHLRQHPAIAEAAAIALETETGRYELAAYLTLVDKAQAPGVEALRNFLQ 1036
Query: 430 SALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXX 488
YM+P + +PL + K+DR+ L DA V V+ +
Sbjct: 1037 ERTPDYMIPTRWSILAQMPLTASNKIDRRAL--------PGCDA-VVVNQEARPHRAPNG 1087
Query: 489 XXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGA 548
+VL A +S ++ LGG+S+ ++ +LR G+ +E+
Sbjct: 1088 ARETALTEVWRSVLNVA---EISALDDYFALGGDSIKALQISARLRQIGWRMEVRQIFEH 1144
Query: 549 STLGEV 554
++ E+
Sbjct: 1145 RSIAEL 1150
>UniRef50_Q7BQ70 Cluster: Putative peptide synthetase/polyketide
synthase; n=1; Bacillus cereus|Rep: Putative peptide
synthetase/polyketide synthase - Bacillus cereus
Length = 2562
Score = 188 bits (459), Expect = 4e-46
Identities = 143/464 (30%), Positives = 234/464 (50%), Gaps = 30/464 (6%)
Query: 15 FYFSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVP 74
+ F+ I++LL KAG AYVP++P +PQ RI IL+D+ +++I + + + +S +
Sbjct: 501 YSFNMIISLLGILKAGGAYVPIDPDYPQERIDFILQDSGSNVIITSNLFEDKVKFDSTML 560
Query: 75 FASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
F EEL + PM + +++A V+YTSG+TG PKGV + +S + +
Sbjct: 561 F--IEEL--------NETPMQDFERVDVAPNNLAYVIYTSGTTGRPKGVMIEHSNVIQLV 610
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI-- 192
Q +F +S S ++ + + F SV EI+G L +G L++ ++ET RD KL +
Sbjct: 611 MHQPNSFKFS-SNDVWLLFHSFCFDMSVWEIFGSLTYGGRLVLATKETIRDTYKLAQLIA 669
Query: 193 -ERLVLVPTLLRSILMYLALGPASRPLR-RLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
E + ++ + ++ + L +++L GE L L +FK N
Sbjct: 670 DEGVTVLNQTPSAFYVFQQVAEEMPKLAFKIRLITFGGEMLKPGLLQSWFKRSPNT---V 726
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
+ N YG TE VTY + G ++ + IG PL + Y+ D+ ++PT GE+
Sbjct: 727 IVNMYGITETTVHVTYMEI-GEKEMHSNLS-AIGVPLPTYSCYVFDKHMNPTPKGMQGEL 784
Query: 311 WVAGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQ 367
+V G +A GY+ N RF NP+ P +RLYR+GD +++ G + Y GR+D Q
Sbjct: 785 YVGGHGVARGYLNRPELNSERFIQNPY--NPS-ERLYRSGDLVRILENGEMEYIGRSDHQ 841
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VKIRG+R++ E+E L Q V + VVL E+ ++ T S +
Sbjct: 842 VKIRGYRIETGEIEHHLQQHADVKEAVVLSIAFGE-EQELCAYILTDQD--ISQNELRYY 898
Query: 428 LRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNND 470
L + YM+P + + +PL NGKV+R+ L K + ND
Sbjct: 899 LTDKIPSYMIPMYFVLLSEMPLTTNGKVNRRALPKPTKLVQPND 942
>UniRef50_Q70C47 Cluster: Polyketide non-ribosomal peptide synthase;
n=2; Xanthomonas albilineans|Rep: Polyketide
non-ribosomal peptide synthase - Xanthomonas albilineans
Length = 6879
Score = 188 bits (459), Expect = 4e-46
Identities = 150/450 (33%), Positives = 225/450 (50%), Gaps = 36/450 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+MALLA +KAGA YVP++P++P IL + + S+V+ D E G
Sbjct: 3844 LMALLAIFKAGACYVPIDPAYPAAYREQILAEVQVSIVLEQDEL---ALDEQG------- 3893
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A P+ L D +A V+ TSGSTG PKGV + Y+ + N L ++
Sbjct: 3894 QFHNPRWREQAPTPLG---LREHPGD-LACVMVTSGSTGRPKGVMVPYAQLYNWLHAGWQ 3949
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
P+ E + + KT++ F SV E+ LL G ++L E +D L +
Sbjct: 3950 RSPFEAGERV-LQKTSIAFAVSVKELLSGLLAGVEQVMLPDEQVKDSLALARAIEQWQVT 4008
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
RL LVP+ L+++L A L L+ V +GE L + +L N
Sbjct: 4009 RLYLVPSHLQALLD--ATQGRDGLLHSLRHVVTAGEALPSAVRETVRARLPQ---VQLWN 4063
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + D TY+ SD + +PIG P+ N +Y+LD +L GE+ V
Sbjct: 4064 NYGCTE-LNDATYH---RSDTVAPGTFVPIGAPIANTEVYVLDRQLRQVPIGVMGELHVH 4119
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKI 370
+A GY G A+RF +P++ +P RLY+TGD L G + Y GR D +VK+
Sbjct: 4120 SVGMARGYWNRPGLTASRFIAHPYSEEPG-TRLYKTGDMVRRLADGTLEYLGRQDFEVKV 4178
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RGHRVD +VE AL P V + VV + +D G+ +++ +V + G SA ++ +L +
Sbjct: 4179 RGHRVDTRQVEAALRAQPAVAEAVVSGHRVD-GDMQLVAYVVAREGQAPSAGELKQQLSA 4237
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGL 459
L YM+P V + +E +P L NGK+DR L
Sbjct: 4238 QLPTYMLPTVYQWLEQLPRLSNGKLDRLAL 4267
Score = 184 bits (447), Expect = 1e-44
Identities = 151/452 (33%), Positives = 226/452 (50%), Gaps = 40/452 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+MALLA +KAGA YVP++P++P IL + + S+V+ E G + +
Sbjct: 5922 LMALLAIFKAGACYVPIDPAYPAAYREQILAEVQVSIVL-----------EQGE--LALD 5968
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW--WQ 137
E Q ++ L D +A V+ TSGSTG PKGV + Y+ + N L WQ
Sbjct: 5969 EQGQFRNRRWREQAPTPLGLRGHPGD-LACVMVTSGSTGRPKGVMVPYAQLHNWLHAGWQ 6027
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------ 191
F ++ E + KT++ F SV E+ LL G ++L E +D L
Sbjct: 6028 RSAF---EAGERVLQKTSIAFAVSVKELLSGLLAGVGQVMLPDEQVKDSLALARAIEQWQ 6084
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ RL LVP+ L+++L A L L+ V +GE L + +L
Sbjct: 6085 VTRLYLVPSHLQALLD--ATQGRDGLLHSLRHVVTAGEALPSAVGEAVRVRLPQ---VQL 6139
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE + D TY+ SD + +PIG P+ N +Y+LD +L GE+
Sbjct: 6140 WNNYGCTE-LNDATYH---RSDTVAPGTFVPIGAPIANTEVYVLDRQLRQVPIGVMGELH 6195
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQV 368
V +A GY G A+RF +P++ +P RLY+TGD L G + Y GR D +V
Sbjct: 6196 VHSVGMARGYWNRPGLTASRFIAHPYSEEPG-TRLYKTGDMVRRLADGTLEYLGRQDFEV 6254
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RGHRVD +VE AL P V + VV + +D G+ +++ +V + G SA ++ +L
Sbjct: 6255 KVRGHRVDTRQVEAALRAQPAVAEAVVSGHRVD-GDMQLVAYVVAREGQAPSAGELKQQL 6313
Query: 429 RSALTHYMMPQVIE-VESIPLLVNGKVDRQGL 459
+ L YM+P V + +E +P L NGK+DR L
Sbjct: 6314 SAQLPTYMLPTVYQWLEQLPRLSNGKLDRLAL 6345
Score = 44.4 bits (100), Expect = 0.012
Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 57 VIYDDSADPSMFKE----SGVPFASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLY 112
V+ DD AD S F +G A+F +L +E+TS S L P + A++L+
Sbjct: 175 VLLDDVADRSAFARMAHAAGTFLATFADLKRESTSAS---------LCPASPSDAALLLF 225
Query: 113 TSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSEEICVW 152
TSGS+G KG+ LS+ + +++ R + + + W
Sbjct: 226 TSGSSGESKGILLSHRNLHHQIQAGIRQWSLDEHSHVVTW 265
Score = 44.4 bits (100), Expect = 0.012
Identities = 26/104 (25%), Positives = 45/104 (43%)
Query: 303 RDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVLYAG 362
R E GE+WV +A GY+ A++ N + +RTGD G + G + G
Sbjct: 446 RPDEIGEIWVKSPAIARGYLFAKPADQRQFNCSIRHTDDSGYFRTGDLGFIADGCLYVTG 505
Query: 363 RTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPE 406
R + IRG +E ++A + + + ++R + E
Sbjct: 506 RVKEVLIIRGKNHYPAHIEASIAATASPGALMPVVFSIERQDEE 549
Score = 37.9 bits (84), Expect = 1.0
Identities = 51/205 (24%), Positives = 84/205 (40%), Gaps = 27/205 (13%)
Query: 337 TQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVV 395
TQP LY+T L G + + G D Q +I R+DL VE L V + VV
Sbjct: 5175 TQPAC--LYKTDALVRRLANGQLEWLGSLDVQSRIDDPRIDLCVVEAQLRLCEDVGEAVV 5232
Query: 396 LCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH----YMMPQV-IEVESIPLLV 450
L L R ++ +++ + A ++R AL+ Y++P + + + P L
Sbjct: 5233 LYEPLKRC---LVAYLSARSTAAIMTDETLARIRQALSETLPDYLLPAIWVPLAHWPRLP 5289
Query: 451 NGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGT- 509
+G+VD L A D D + V + R + T
Sbjct: 5290 HGRVDLGAL--------------PAPDFDLA-RHESYIAPRTAVEQAVAEIWQRVLKRTQ 5334
Query: 510 LSLRSGFYELGGNSLNSIYTITKLR 534
+ + F+ELGG+S+ +I ++ LR
Sbjct: 5335 VGVHDNFFELGGHSVLAIQLVSGLR 5359
>UniRef50_A5W126 Cluster: Amino acid adenylation domain; n=2;
Pseudomonas|Rep: Amino acid adenylation domain -
Pseudomonas putida F1
Length = 1405
Score = 188 bits (459), Expect = 4e-46
Identities = 143/456 (31%), Positives = 228/456 (50%), Gaps = 25/456 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ + A KAG AYVP++P++P R+ ++++D+ ++ A P + VP A
Sbjct: 571 VVGIFAILKAGGAYVPLDPAYPADRLAYMIEDSGLQRLL----AQPQVLASLPVP-AGVR 625
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L+ E++ S A + ++ D++A V+YTSGSTG PKGV L +
Sbjct: 626 VLSLESSDDSTQADPLACSPVTVSPDNLAYVIYTSGSTGKPKGVLLPQRNVLRLFTATDA 685
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIERLV 196
F + S+++ + F SV EI+G LL+G L+I+ + T+R P+ +L+ E++
Sbjct: 686 DFRFG-SDDVWSLFHSYAFDFSVWEIFGALLYGGRLVIVPQHTSRSPEAFYQLLADEQVT 744
Query: 197 LV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
++ P+ + ++ RPL L+ V GE L + +F+ FG+ +L N
Sbjct: 745 VLNQTPSAFKQLMAVATTAEPQRPLA-LRSVVFGGEALDVNSLAPWFERFGDRQP-QLVN 802
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE V+Y L +D L + P+G P+ + + Y+LD +L+P GE++V
Sbjct: 803 MYGITETTVHVSYRPLSRAD-LGKAASSPMGVPIPDLSWYVLDGDLNPVAKGCIGELYVG 861
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
A LA GY+ A RF +P RLYRTGD G + YAGR D QVKI
Sbjct: 862 RAGLARGYLKRSDLSATRFVPDPFGAPGG--RLYRTGDLARYHADGVIEYAGRIDHQVKI 919
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLR- 429
RG R++L E+E L P V + +VL G + + A + +LR
Sbjct: 920 RGFRIELGEIEARLQAQPQVREALVLAQEGATGQQLVAYLIPAAEVALEQQAGLRAQLRE 979
Query: 430 ---SALTHYMMP-QVIEVESIPLLVNGKVDRQGLLK 461
AL YM+P ++ ++ PL NGK+DR+ L K
Sbjct: 980 QLKEALPDYMVPAHLLLLDRWPLTANGKLDRKALPK 1015
>UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5;
root|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 3235
Score = 188 bits (459), Expect = 4e-46
Identities = 150/510 (29%), Positives = 251/510 (49%), Gaps = 38/510 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ AL++ K+G AY+PM+P FP+ R+ ++L++A+ +++ DS + +
Sbjct: 1192 LTALVSIHKSGGAYLPMDPVFPKDRLEYMLENAQVPIIL-TDSIIKETLPANQAKILCID 1250
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E + + SA++P + +T D++A V+YTSGSTG PKGV++ + A+ N L
Sbjct: 1251 EEWNKISVQSAEKPENR-----VTQDNLAYVIYTSGSTGNPKGVQIEHRALTNFLLSMGT 1305
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
+ + + + T L+F + E+ PL+ G +++I R+ D +KL+ + +
Sbjct: 1306 STNMCEKDRLLA-VTTLSFDIAGLEMLLPLVTGASVIIAGRDEVIDGEKLIALMDKHDIS 1364
Query: 200 TLLRSILMY-LALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + + L + + LK+ +C GE L ++LA+E L N YG T
Sbjct: 1365 VMQATPATWRLLVEEEWQGCSSLKI-LCGGEALPRDLANELMVRCSC-----LWNVYGPT 1418
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T L + + IG+P+ N +Y+LD E+ PT PGE+++ G LA
Sbjct: 1419 ETTIWSTMVRLNSKEG-----QVSIGKPIANTTVYVLDNEMKPTPVGIPGELYIGGTGLA 1473
Query: 319 AGY--VGGGGANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGHRV 375
GY + +F NP +++ E RLY+TGD + G + + GR D QVKIRG R+
Sbjct: 1474 RGYLKLPELTQEKFIPNPFSSE-EGSRLYKTGDIVRFMPDGNIEFIGRGDHQVKIRGFRI 1532
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E+E L + P + + VV+C + G ++ +V K T+A LR+ L Y
Sbjct: 1533 ELGEIETLLNKNPLISQSVVVCREISLGEKALIAYVIPK-SQETAATTFREYLRNRLPDY 1591
Query: 436 MMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXX 494
M+P + ++S P+ N K+DR+ L M E T A+ S
Sbjct: 1592 MIPSYFVILDSFPMTPNNKIDRKS-LPMPEKT--------AIGAS-SVMMQPLNDVQKTV 1641
Query: 495 XXTVGAVLGRAARGTLSLRSGFYELGGNSL 524
T VLGR + L F++LGG+SL
Sbjct: 1642 SDTWKEVLGRE---NIGLNENFFDLGGHSL 1668
Score = 66.1 bits (154), Expect = 3e-09
Identities = 68/286 (23%), Positives = 124/286 (43%), Gaps = 23/286 (8%)
Query: 284 GRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQR 343
G P+ +C + + D + + +++ G + ++GAN+ +GY A R T+ +
Sbjct: 374 GYPIYDCYVRICDIDNNDIGENKIGYICISGANVTSGYYNNKEATRKA----ITKDGW-- 427
Query: 344 LYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDR- 402
TGD G + G ++ GR + ++G ++ER +V G+D ++ G
Sbjct: 428 -LNTGDLGFMRDGRLVITGRAKDVIFVKGQNYYSHDIERVAQEVDGIDVGKIVAVGAFNE 486
Query: 403 --GNPEILGFVTTKPGARTSAQHIEG--KLRSALTHYMMPQVIEVESIPLLVNGKVDRQG 458
+ E++ FV K + KL S + QVI ++SIP +GKV R
Sbjct: 487 KIKSDELILFVLFKMKVDKFIGLVRSLKKLISERMGIEVSQVIPIKSIPKTTSGKVQRYK 546
Query: 459 LLK-----MYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLR 513
L + Y+ N+ + + + +C VLG G ++
Sbjct: 547 LRESYIKGQYDTIKNDIELLLKSEAECRLIDQPENEIQAKLVEIWQEVLGLKRIG---IK 603
Query: 514 SGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGEVLSKMS 559
F+ELGG+SL I+++R+ + VE+ L T VLS+++
Sbjct: 604 DNFFELGGDSLKLTQIISRIREE-FEVELEQTLLFET--PVLSELA 646
>UniRef50_Q93H59 Cluster: Non-ribosimal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosimal peptide
synthetase - Streptomyces avermitilis
Length = 1709
Score = 188 bits (458), Expect = 5e-46
Identities = 165/555 (29%), Positives = 252/555 (45%), Gaps = 38/555 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ALLA W+AGA YVP++P+ P R++ + ++A LV+ A P++ V A
Sbjct: 68 IVALLAVWRAGAGYVPLDPAQPPARLSDLAREAGARLVV----AGPAL--AGPVRDAGAR 121
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E + +P A L + A ++TSGSTG PK V ++++ I NR+ W +
Sbjct: 122 RVGPEEIPDRSSDP--AGPLPAADPANAAYAVFTSGSTGRPKAVVVTHAGIANRIGWTVQ 179
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLVL 197
++ + + KT + F + EI+ PL+ G +++ RDP L+ + V
Sbjct: 180 RHALGAADRV-LQKTTIGFDAAGWEIFAPLVGGGTVVLAPAGAERDPAALLRAVADHGVT 238
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V ++ S+L L L+L +GE L EL + + G + ++ N YG
Sbjct: 239 VLQVVPSVLRLLVEEGDWSGCGSLRLLFSAGEALHAELVARLRERTGQD--LEVWNTYGP 296
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE D+T +++ + L P +PIGRPL + +L P PGE++ G +
Sbjct: 297 TECSIDITAQLVDPA--LTAGP-VPIGRPLPGMRVLVLGPNGVPVPVGVPGELYAGGVGV 353
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHR 374
A GY G A+RF +P+AT+P RLYRTGD L Y GR D QVK+ G R
Sbjct: 354 ARGYAGRPDLTADRFVPDPYATEPG-ARLYRTGDQVRWRSDRTLEYLGRLDHQVKVNGVR 412
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++ EVE ALA P V VV Y D G + ++T A + + G L L
Sbjct: 413 IEPAEVEAALAAHPAVTGAVVTPYEADGGGKRLAAYLTVSGEADPAG--LRGFLAERLPD 470
Query: 435 YMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+P + +++ PL NGKVDR L AE+A
Sbjct: 471 SHVPSFLHTLDAFPLTANGKVDRAAL---------PSPAEIAA-AGQPTYTAPRDAAEEL 520
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEISDFLGASTLG 552
+LG G L F+ LGG SL +LR G V + A+T+
Sbjct: 521 VAGVWADLLGLDRVGAL---DDFFALGGTSLQLTRLAARLRAASGEKVSLRGLFAATTV- 576
Query: 553 EVLSKMSTDPNGGAD 567
+ +++ P G AD
Sbjct: 577 QAQAQLIGTPTGAAD 591
Score = 188 bits (458), Expect = 5e-46
Identities = 142/447 (31%), Positives = 207/447 (46%), Gaps = 23/447 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ALLA WKAG AYVP++PS+P RI + A + SA + F SG +
Sbjct: 1156 VTALLAVWKAGGAYVPVDPSYPAERIAAMCDTAGVRTAV-TTSAYAARFTSSGTRLLLLD 1214
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A + A P A T P +A ++TSGSTG PKGV +++ + N + W R
Sbjct: 1215 TDADDIAGRPAAAP--ARTRDPRR---LAYTIFTSGSTGTPKGVEVTHQGLANHVAWAAR 1269
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP--QKLVNIERLVL 197
D ++ +A F V +W PL+ G+ L +L ++T ++L +
Sbjct: 1270 ELAGQDYGGGALFSSA-AFDLVVPNLWAPLVTGQRLFLLPQDTDMSELGKRLAEAQPFSF 1328
Query: 198 VPTLLRSI-LMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V + ++ L L PA L V +GE ++ ++ +L N YG
Sbjct: 1329 VKLTPGHLDILALQLTPAQAGALAPVL-VVAGEAFTRATLE---RWRALAPDTRLINEYG 1384
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T Y + D+ +PIGRPL N +Y+LD L P GE++V G
Sbjct: 1385 PTEASVGTTVYEIPEHADADV---LPIGRPLPNMRVYVLDPALQPVPVGVAGELYVGGTG 1441
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+A GY A+RF +P+ T P R+YRTGD L G V + GR D QVKIRG+
Sbjct: 1442 VARGYANRPDLTADRFLPDPYGTGPG-ARMYRTGDLVRHLPDGNVAFLGRVDDQVKIRGY 1500
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
RV+L E++ L P V VV + + G P + V A + + L
Sbjct: 1501 RVELGEIQAVLTAHPAVRDAVVTVHRPENGEPTLAAHVVPADAA-APLPDLAAHCAARLP 1559
Query: 434 HYMMPQVI-EVESIPLLVNGKVDRQGL 459
YM+P +++IP+ NGKVDR L
Sbjct: 1560 EYMIPATFTALDTIPVNANGKVDRSAL 1586
>UniRef50_Q47NS1 Cluster: Amino acid adenylation; n=1; Thermobifida
fusca YX|Rep: Amino acid adenylation - Thermobifida fusca
(strain YX)
Length = 1344
Score = 188 bits (458), Expect = 5e-46
Identities = 172/562 (30%), Positives = 255/562 (45%), Gaps = 57/562 (10%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ L A KAG AYVP++ +P GR+ +L DA P+L + +A + +SG +
Sbjct: 528 VVTLFAVLKAGGAYVPLDLEYPAGRLRVMLADAAPALTVTTTAARGHLPADSGPLLLLDD 587
Query: 80 ELAQEATSHSAD-EPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
++ + AD +P DA+ PL D +A ++TSGSTG PKGV+++ + N L
Sbjct: 588 PAIRDELARMADTDPTDADRPRPLRGDHLAYTIFTSGSTGRPKGVQITGRGLVNMLVNHR 647
Query: 139 RTF--PYSDSEEICVWKTALTFVDSVCEIWGPLL---HGRALLILSRETTRDPQKLVN-- 191
T P DS V + A T S W LL G + +L E RD +LV+
Sbjct: 648 ETIFGPVVDSLGGRVLRIAHTVSFSFDMSWEELLWLVDGHEVHLLDEELRRDSDRLVDYC 707
Query: 192 ----IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNED 247
I+ + + P+ ++ L P R L + GE +S + ++ +
Sbjct: 708 RRHSIDVINVTPSYCGQLIEDGLLDPDQY---RPSLVLLGGEAVSDTV----WQALRGAE 760
Query: 248 GYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEP 307
G N YG TE T L G PT+ G P+ N +Y+LD L P P
Sbjct: 761 GVLGYNLYGPTEY----TINTLGGGTADSATPTV--GGPIANTQVYVLDSALRPVPPGTP 814
Query: 308 GEVWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRT 364
GE++V+G LA GY+G A RF NP P R+YRTGD G + Y GR
Sbjct: 815 GELYVSGVGLARGYIGRADLTAERFVANPFG--PPGSRMYRTGDLVRWRPDGHLDYLGRV 872
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHI 424
D QVKIRG RV+ E+ L + P V + V+ G +++G+V GAR +
Sbjct: 873 DDQVKIRGVRVEPAEITAVLEEQPEVAQAAVVVREDTPGRAQLVGYVVPAAGARIDPAAL 932
Query: 425 EGKLRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL----LKMYENTNNNDDAEVAVDID 479
L + M+P ++E++ +PL VNGK+DR L L D+ E A+
Sbjct: 933 RRTLADLVPAAMLPAHLVELDRLPLTVNGKLDRAALPAPALPERGGRAPRDELERAL--- 989
Query: 480 CSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GY 538
C V AVL +S+ FYELGG+SL ++ +LR G
Sbjct: 990 CEH---------------VAAVLN---VDQVSIDDDFYELGGHSLLAMRLAARLRKHVGV 1031
Query: 539 YVEISDFLGASTLGEVLSKMST 560
V + L A T+ ++ + T
Sbjct: 1032 RVGVGTLLAAPTVAQLREYVDT 1053
>UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria
(class)|Rep: Peptide synthetase - Streptomyces fradiae
Length = 5246
Score = 188 bits (458), Expect = 5e-46
Identities = 146/453 (32%), Positives = 218/453 (48%), Gaps = 23/453 (5%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYD-DSAD-----PSMFKESGVP 74
+ALLA WKAG Y+P++P P+ R+ +L D+ P VI D A P+ P
Sbjct: 3156 VALLAVWKAGLHYLPLDPDHPRSRLADVLADSAPGCVITTTDLARRLPPVPAPLLVLDDP 3215
Query: 75 FASFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRL 134
A+ LA + A++P + + +A +YTSGSTG PKGV ++ SA+ N L
Sbjct: 3216 -ATAARLAATTATALAEDPREQNGE---WGEELAYTIYTSGSTGRPKGVMVTRSAVANFL 3271
Query: 135 WWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIER 194
+ + T ++F +V E+ PLL G +++ T RDP + ++
Sbjct: 3272 ADMNERLELGPGDRLLA-VTTVSFDIAVLELLAPLLTGGTVVLADATTQRDPAAVRSLCA 3330
Query: 195 LVLVPTLLRSILMYLALG-PASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V + + + A+ L L++ V GE L LA + G L N
Sbjct: 3331 REGVTVIQATPSWWHAMAVDGGLDLTALRVLV-GGEALPPALARTLLEPGRAPLGDYLLN 3389
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYP-TIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
YG TE T + +D L+ + +P G P+ A Y+LD L P D PGE+++
Sbjct: 3390 LYGPTETTVWSTVARIT-ADSLEAHGGAVPTGTPIARTAAYVLDAALRPVPDGVPGELYL 3448
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
AGA LA GY+G G A RF P E R+YRTGD G + + GRTD QVK
Sbjct: 3449 AGAGLARGYLGRPGMTAERFVACPFGEPGE--RMYRTGDLARWRADGNLEHLGRTDDQVK 3506
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKL 428
+RG R++L EVERAL Q GV + + G+ ++G++ G+ + + +
Sbjct: 3507 VRGFRIELGEVERALTQAHGVGRAAAAVHPDAAGSARLVGYLVPAGGSGALDEKAVADAV 3566
Query: 429 RSALTHYMMPQVIEV--ESIPLLVNGKVDRQGL 459
R+ L YM+P + V +PL NGK+DR L
Sbjct: 3567 RAVLPAYMVPSALVVLDGGLPLTANGKLDRAAL 3599
Score = 186 bits (454), Expect = 2e-45
Identities = 144/448 (32%), Positives = 215/448 (47%), Gaps = 29/448 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ LL K+GAAYVP++ +P R+ +L+D P+LV+ +A +ESG +
Sbjct: 2093 LAVLLGVLKSGAAYVPLDEQWPAERLRTVLEDCRPALVLAPTAARSDAARESGATVLPVD 2152
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
A A H P DAE + PLT + A LYTSGSTG PKGV + +SA+ + R
Sbjct: 2153 PAALAA--HGPQTPTDAERIRPLTPGAAAYALYTSGSTGRPKGVVIDHSALAAYVGGARR 2210
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSR-ETTRDPQKLVNIERLVLV 198
+P D+ + T+L F +V + PL G A+ + ET RD
Sbjct: 2211 RYP--DAAGTSLAHTSLAFDLTVTTLLTPLTAGGAVRLGELDETARDAGA---------- 2258
Query: 199 PTLLRSILMYLAL-GPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL+++ +L L L + GE L+ + + + ++ N YG
Sbjct: 2259 -TLVKATPSHLPLLSELPGALNDGGTLILGGEALTGGRLRPWRELHPDA---QVVNAYGP 2314
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE+ + T Y L + + P +PIGRP +++L L P PGE++V+G +
Sbjct: 2315 TELTVNCTEYRLPKGEPVGEGP-VPIGRPFAGVRVHVLGPGLRPVPAEVPGELYVSGVGV 2373
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
A GY+G A RF P E R+YRTGD G + Y GR+D QVK+RG R
Sbjct: 2374 ARGYLGRPALTAERFVACPFGEPGE--RMYRTGDLVRWRSDGQLEYVGRSDDQVKLRGFR 2431
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLRSALT 433
V+ EV RAL P V +V+ G+ ++G++ G+ + + +R+ L
Sbjct: 2432 VETAEVARALETCPSVGSAMVVLREDQPGDQRLVGYLVPAAGSGALDKEAVSDAVRAVLP 2491
Query: 434 HYMMPQVIEV--ESIPLLVNGKVDRQGL 459
YM+P + V + PL VNGKVDR L
Sbjct: 2492 EYMVPSALVVLEDGPPLTVNGKVDRSAL 2519
Score = 173 bits (422), Expect = 1e-41
Identities = 162/538 (30%), Positives = 245/538 (45%), Gaps = 44/538 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I AL+A KAGAAYVPM+ P RI H+L++A P LV+ + ++ + +G P +
Sbjct: 4240 ITALVAVQKAGAAYVPMDAELPAERIAHMLENARPVLVLAHTATQDALPEGAG-PVVRLD 4298
Query: 80 ELAQEATSHSAD--EPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
A EA D + DA+ AP T A V+YTSGSTG PKGV + ++ L
Sbjct: 4299 APAIEAALAGLDGGDCTDADRRAPATHHDPAYVVYTSGSTGTPKGVVVEQRSLAAFLVRS 4358
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETT-RDPQKLVNIERLV 196
Y + + + F +V ++ PL+ G +++ + RD ++ L
Sbjct: 4359 AAR--YRGAAGTALLHGSPAFDLTVTTLFTPLIAGGCIVVADLDAPERDAPARPDL--LK 4414
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ P+ L ++L +A + P L V GE L+ AS + ++ N YG
Sbjct: 4415 VTPSHL-ALLDTIASW--ATPAADL---VVGGEQLT---ASRLARLRRAHPDMRVFNDYG 4465
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE +VLE D T+PIGRPL +++LD+ L P + PGE++V+G
Sbjct: 4466 PTEATVSCADFVLEPGDAPPT-DTVPIGRPLAGHRLFVLDDRLRPVPANVPGELYVSGVG 4524
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQVKIRGH 373
+A GY+G G A RF P E R+YRTGD G + Y GR D QVK+RG
Sbjct: 4525 VARGYLGRPGMTAERFVACPFGEPGE--RMYRTGDLARRRADGNLEYLGRRDGQVKVRGF 4582
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
RV+ E+E AL P + + V+ G +L +V P R + L S L
Sbjct: 4583 RVETGEIETALLDRPEIGQAAVVLRG-----ERLLAYVAAPP-ERFDPDALRQALASRLP 4636
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P + ++++PL GK+D + L + + + D
Sbjct: 4637 RYMVPAAFVRLDALPLAPGGKLDHRALPEPPAPADAPHGSRPPRD-----------AWEG 4685
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
G VLG A G F+ LGG+S+ SI + ++R G + + D T
Sbjct: 4686 VLCEAFGEVLGIAEVGA---DDDFFALGGDSIGSIRLVGRVRAAGGRMTVRDIFEQRT 4740
Score = 154 bits (374), Expect = 8e-36
Identities = 139/457 (30%), Positives = 206/457 (45%), Gaps = 36/457 (7%)
Query: 23 LLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEELA 82
+LA ++GA +VP++P P R+ + +D P LV+ + + + ++ + P ++ +
Sbjct: 544 VLAVLRSGAVHVPLDPRSPHERLAAVERDVAPLLVLAERATEAAV-ADLAAPVLVLDDPS 602
Query: 83 QEATSHSADE-PM-DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
EA + D P+ DA+ APL A V++TSGSTG PKGV + + + +RL R
Sbjct: 603 TEAAIDALDPGPVTDADRTAPLLPGHAAYVIHTSGSTGRPKGVTVDHRGL-SRLLQAHRR 661
Query: 141 FPYSDSEEICVWKTALTFVDSVC--EIWGPLLH---GRALLILSRETTRDPQKLV----- 190
+S V S W PLL G L ++ + DP +V
Sbjct: 662 VTFSRIRPSAGGPGRAAHVSSFSFDASWDPLLAMVAGHELHMIDEDLRFDPPGVVAYFRD 721
Query: 191 -NIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
I+ + L PT RS+L G L GE + EL + +
Sbjct: 722 RRIDYVDLTPTYFRSLL---DAGLLEEGFPCPSLVALGGEAMDGEL---WERLRAAAPRV 775
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
N YG TE D VL DL P IGRP+ Y+LD L P GE
Sbjct: 776 TAMNTYGPTETAVDAVVTVLG-----DLPPGT-IGRPVPRWRAYVLDAGLRPVPPGVLGE 829
Query: 310 VWVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDA 366
+++AG +A GY+G A RF P E R+YRTGD L G ++Y GR D
Sbjct: 830 LYLAGPGVARGYLGQHALTAERFVACPFGKPGE--RMYRTGDLARWLPDGHLVYVGRGDE 887
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKP---GARTSAQH 423
QVKIRG R++ EVE AL ++ GV V G ++G+V P AR
Sbjct: 888 QVKIRGFRIEPGEVEAALRELEGVAAAAVTVREDTPGTRRLVGYVVGTPDADDARLRPAE 947
Query: 424 IEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ +LR L +++P + + +P+ +GK+DR L
Sbjct: 948 VLARLRDRLPDHLVPSAFVRLRELPVNTSGKLDRAAL 984
>UniRef50_Q0LKI6 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1569
Score = 188 bits (458), Expect = 5e-46
Identities = 147/526 (27%), Positives = 238/526 (45%), Gaps = 33/526 (6%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
TI+ +LA KAG AY+P++P+ PQ RI +L DA+ LV+ + +P A
Sbjct: 561 TIIGILAILKAGGAYLPIDPAHPQERIVWLLADAKVGLVVTQARC------VNKLPQAGL 614
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ + +A + + A D +A ++YTSGSTG PKG +++ + RL+
Sbjct: 615 QLIVLDAVDSALSNQPTSNLPASAQLDDLAYMIYTSGSTGTPKGALITHRNVA-RLFSST 673
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLV 196
+ ++ ++ + F SV EIWG LL+G ++++ TTR+P ++ V
Sbjct: 674 EAWFNFNNHDVWSLFHSFAFDFSVWEIWGALLYGGRVVVVPFMTTRNPAGFYQLLVDEGV 733
Query: 197 LVPTLLRSILMYLALGPASRPLRR---LKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
V S L + A L L+ + GE L+ +F+ G+ +L N
Sbjct: 734 TVLNQTPSAFRQLIISDAEHDLPSRLALRYVIFGGEALNVGALQPWFERHGDLRP-QLVN 792
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTY L D ++ + PIG + + +Y+LD+ P GE++V
Sbjct: 793 MYGITETTVHVTYRPLSMHD-VENPQSSPIGTAIPDLDLYVLDDHCLPVPLGITGELYVG 851
Query: 314 GANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKI 370
GA LA GY RF +P A E RLY+TGD L + Y GR D QVKI
Sbjct: 852 GAGLARGYWNRPELTNERFIKHPFA---ETGRLYKTGDLVRRLANNEIEYLGRRDNQVKI 908
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E++ L P + +V + + ++ ++ T+P + L+
Sbjct: 909 RGFRIELGEIQATLMSHPAITDAIVAVNTISADDQRLVAYLVTQPNQVPRFSQLRTFLKQ 968
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P I +E IPL NGK+D + L + +A +
Sbjct: 969 RLPEYMVPTSFIMLERIPLTANGKIDYRALPSQQQTKQLERSQPIAAPTSVTEQSLIAIW 1028
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
VG ++ F++LGG+SL + I+++R+
Sbjct: 1029 SNLLGVTQVG------------IQDNFFDLGGHSLLATQVISRVRE 1062
>UniRef50_Q08N46 Cluster: Condensation domain protein; n=3;
Stigmatella aurantiaca DW4/3-1|Rep: Condensation domain
protein - Stigmatella aurantiaca DW4/3-1
Length = 2000
Score = 188 bits (458), Expect = 5e-46
Identities = 167/624 (26%), Positives = 281/624 (45%), Gaps = 49/624 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L T KAG AYVP++PS P R+ ++++D+ +++ E +P +
Sbjct: 929 VVGMLGTLKAGGAYVPLDPSVPAERLGYMVEDSGLEVLL------TQAHLEGKLPQGALR 982
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +A + + + ++A V+YTSGSTG PKG L + +CN +
Sbjct: 983 VVRLDADWGEIGQQSQGKVESGSGGGNLAYVIYTSGSTGKPKGTLLEHGGLCNTVREAIE 1042
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ + + +++ F SV E++ LL G L + +E + L + ++ +
Sbjct: 1043 MMELGPGKRVLQF-SSMGFDASVWEMFSALLSGARLEMAPKEALQPGAPLQELLKQKEIT 1101
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL ++LM L R L +LK +GE + EL + ++G + N YG
Sbjct: 1102 TATLTPAVLMQLE----PRELPKLKTVAAAGEASTGELVRRW------KEGRRFINAYGP 1151
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TEV T + + PTI GRPL N +Y+LDEE + GE+ V G +
Sbjct: 1152 TEV----TICATKNGQVEERRPTI--GRPLKNVQVYVLDEEQNEVPVGVAGELCVGGVGV 1205
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVKIRGHR 374
GY G A RF +P + Q RLYRTGD V+G L + GR D QVK+RG R
Sbjct: 1206 GRGYQGRPELTAERFIPHPFS-QEAGARLYRTGDRARYVEGGELEFLGRMDFQVKLRGFR 1264
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK-PGARTSAQHIEGKLRSALT 433
++L EVE L + PGV + VV+ + G+ ++ +V K + S++ + L+ L
Sbjct: 1265 IELEEVEGVLGKHPGVREVVVVVREDEGGSRRLVAYVVGKQKESAPSSESLRSYLKEKLP 1324
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL-LKMYENTNNNDD-AEVAVDIDCSXXXXXXXXX 490
YM+P + +E++PL + GKVDR+ L + + + E +++
Sbjct: 1325 EYMVPSAYVRLEALPLALTGKVDRRALPVPTLDGAGRREGFVEPRTELE----------- 1373
Query: 491 XXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
V A + + AR + + F+ELGG+S++S+ + + G V T
Sbjct: 1374 --RKLAEVWASVLKHAR--VGVHDNFFELGGDSISSMQIVARAHQAGLKVTSKQLFQHQT 1429
Query: 551 LGEVLSKMSTDPNGGADSKEATFTAVPMRD-EHKKEVIDMVESSFYEKAELEQFLKHEIE 609
+ E+ + G TA+ + + + ++ + E A LE+ LK +
Sbjct: 1430 IAELAPVVDVSREQGMARDSMPLTAIRRGNADAARPMVSDFPLARMEPATLERVLKKHPQ 1489
Query: 610 TRDYADCIDACWPALLQAGLSVVL 633
D L A LSV L
Sbjct: 1490 VEDIYPLSPLQQGMLFHALLSVEL 1513
>UniRef50_A6EWZ1 Cluster: Peptide synthetase; n=1; Marinobacter
algicola DG893|Rep: Peptide synthetase - Marinobacter
algicola DG893
Length = 1501
Score = 188 bits (458), Expect = 5e-46
Identities = 155/547 (28%), Positives = 258/547 (47%), Gaps = 40/547 (7%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
+ + A++ K GA Y+P++P FP+ R+ H+++D+E S VI D ++ V
Sbjct: 526 AALAAIIGILKLGAIYLPLDPDFPEARLQHMIEDSEASAVIVDPQTPAAIAGLDLVKVDI 585
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
E + Q A + S+ P++ +AP + A ++YTSGSTG PKGV + + A+ N L
Sbjct: 586 NEAVNQNAAASSSLPPVN---IAP---EQTAYIIYTSGSTGKPKGVLVPHRALINFLE-S 638
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL--VNIERL 195
P + + + T +F S E+ PL G +I +++ +D +KL + ++
Sbjct: 639 MAEKPGCVATDRLLAVTTFSFDISFLELLLPLTQGATTVIADKDSVKDGEKLRQLILDHQ 698
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + + L + R++ +C GE L ++L + G D +L N Y
Sbjct: 699 ISIMQATPATWRILLDTDWRQDGVRMR-GLCGGEPLPQDLVRDLL---GCLD--ELWNMY 752
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T + L +D+L I IG+P+ N +++LD E +P S PGE+++ G
Sbjct: 753 GPTETTVWSTCHRLRLTDRL-----ISIGQPIGNTQVHILDRECNPLPLSCPGELYIGGL 807
Query: 316 NLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
LA GY + P RLY TGD G + + GR D QVK+RG+R
Sbjct: 808 GLATGY---HNRPELTAEKYVDHPTHGRLYATGDLAKWDPDGNLQHLGRMDDQVKVRGYR 864
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L ++E AL P V + L G+ I+G V ++ G + +I +LR L
Sbjct: 865 IELGDIESALVTCPDVKSACAYVWELSPGDARIVGCVVSESGNEPNVVNIRKELRKVLPA 924
Query: 435 YMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
YM+PQ +I +E++PL +GK+DR+ L K + + + S
Sbjct: 925 YMIPQYIIAIEAVPLSPSGKMDRRRLPK--------PELRESSILKASALANQTEEMIAD 976
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGASTLG 552
V R R F+ LGG+SL ++ I ++ + G + D +G S L
Sbjct: 977 VWSDVLNSKSRIVR-----EDNFFSLGGHSLLALQAIRRIESQTGIKLTPEDIVGLS-LS 1030
Query: 553 EVLSKMS 559
E+ K+S
Sbjct: 1031 EIAEKVS 1037
>UniRef50_A0ZL90 Cluster: Non-ribosomal peptide synthase; n=1;
Nodularia spumigena CCY 9414|Rep: Non-ribosomal peptide
synthase - Nodularia spumigena CCY 9414
Length = 1518
Score = 188 bits (458), Expect = 5e-46
Identities = 140/447 (31%), Positives = 229/447 (51%), Gaps = 35/447 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+++LA KAG AYVP++P++PQ R+ IL+DA+ +++ F +P S +
Sbjct: 531 IISILAVLKAGGAYVPLDPAYPQERLNFILQDAQLPIILTQQH-----FITKLLP-TSAK 584
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + HS +P D + + + SD++A V+YTSGSTG PKGV +++ +CN Q +
Sbjct: 585 IICTDIDIHS--QPSDNPS-SSVKSDNLAYVIYTSGSTGKPKGVMVAHRGLCNLATAQIK 641
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTR--DP-QKLVNIERLV 196
F + + +++F S+ EI + G L + +R++ + P QKL+ I+ +
Sbjct: 642 LFEVRPDSSVLQF-ASISFDASISEIVMAICAGAKLCLATRDSLQPGQPLQKLLQIQNIS 700
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
V TL+ S L AL P P LK + +GE +LA+ + G + N YG
Sbjct: 701 HV-TLVPSALA--ALSPQDLP--NLKNLIVAGEPCPGDLAASWAV------GRQFFNAYG 749
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE T + + + I IG+ + + IY+LD L P PGE+ +AG
Sbjct: 750 PTEATVCATVLLYQPGMK------ISIGQAIAHTQIYILDHYLQPVPIGVPGELHIAGVG 803
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
LA GY+ A +F NP + RLY+TGD G L G + + GR D QVKIRG
Sbjct: 804 LARGYLNQPDLTAQKFIPNPFSNDTN-SRLYKTGDLGRYLPDGNIEFLGRIDNQVKIRGF 862
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E + Q P + + + + G ++ ++ ++ I L+ L
Sbjct: 863 RIELEEIETTIVQHPQIQQAIAIVREDIPGTKRLVAYIVPHQQHSLNSNEIWEYLKHKLP 922
Query: 434 HYMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + + ++S+PL NGK+DR+ L
Sbjct: 923 EYMIPAIFVFLDSLPLTPNGKIDRKSL 949
>UniRef50_Q9FB18 Cluster: Peptide synthetase NRPS2-1; n=1;
Streptomyces verticillus|Rep: Peptide synthetase NRPS2-1
- Streptomyces verticillus
Length = 2626
Score = 188 bits (457), Expect = 7e-46
Identities = 145/455 (31%), Positives = 214/455 (47%), Gaps = 45/455 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A LA KAGAAYVP++P+ P+ R+T +L DA P++V+ P A
Sbjct: 523 VTATLAALKAGAAYVPLDPALPEERLTRVLADARPAVVL--------------TP-AYLH 567
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + E T+H+ + P+ D++A +L+TSGSTG PKGV ++ NR+ W
Sbjct: 568 DRSAEITAHAGH-----DLNLPVHPDNLAYLLHTSGSTGTPKGVLGTHRGAVNRVDWMST 622
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+P+ + ++ V +TA FVD+V E++GPL G L++L + RDP L +
Sbjct: 623 AYPFR-TGDVAVARTAPGFVDAVWELFGPLAAGVPLVLLPTDEARDPALLTAALERHRVS 681
Query: 194 RLVLVPTLLRSILMYLALG-PASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
R+V VP+LL +L A L L+ W+ SGE L LA F G L
Sbjct: 682 RMVTVPSLLTMLLDESARATDLGTRLACLRTWITSGEPLPPALARRFHDRL---PGRTLL 738
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YGS+E D T ++ + L PIG P+ + + +L P PGE++
Sbjct: 739 NLYGSSETAADATAARIDPAPGTALPERSPIGTPITGVSALVRGPDLRPLPALMPGELYA 798
Query: 313 AGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
GA +A GY P R++RTGD L G + GR D QV+IR
Sbjct: 799 GGACVARGYHARPAETAAAFPPDPDGGPGARMFRTGDRARLRADGRLELLGRVDRQVQIR 858
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILG---FVTTKPG---ARTSAQHIE 425
G R + EVE AL P V V NP+ G +V PG A + +
Sbjct: 859 GQRAEPGEVEHALLAHPAVRAAAV------TANPDATGLWAYVRLAPGPFAAGSPQTELT 912
Query: 426 GKLRSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL 459
LR L +++P + V + +P+ +GK D L
Sbjct: 913 AFLRRTLPAHLVPTAVTVLDELPVTAHGKTDHARL 947
Score = 171 bits (415), Expect = 8e-41
Identities = 137/453 (30%), Positives = 227/453 (50%), Gaps = 29/453 (6%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+A L ++GAAY+P++P P R+ H+++ AE +L++ + + ++ GV + ++
Sbjct: 1583 VAALGVLESGAAYLPLDPELPAERLVHLVRRAEAALLLTERALLDTLAVPVGVTVLAVDD 1642
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
+A + P+ +++ LT +A ++TSGSTG PKGV + + N L R
Sbjct: 1643 ---DAALDADGGPL--QSVQNLTD--LAYTIFTSGSTGEPKGVMIDHLGAANTLECVNRR 1695
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIERLVL 197
F + + + +F +V +++G L G +++ + + RDP +L+ ER+ L
Sbjct: 1696 FGTGPGDAVLAVSSP-SFDLAVYDLFGVLAAGGTVVVPAHDRRRDPGHWAELIRRERVTL 1754
Query: 198 ---VPTLLRSILMYL-ALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VP L + Y AL P + LR L+ + SG+ + L + G + +
Sbjct: 1755 WNSVPALGTLLTEYAEALAPDA--LRTLRAVLLSGDWIPLGLPDRIRAL--SAPGATVMS 1810
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
G+TE +Y E + + +IP G P+ N + +LDE+L P D PGE+++
Sbjct: 1811 LGGATEASIWSVWY--EIGKVHEAWSSIPYGTPMANQRLEVLDEQLRPRPDWVPGELYIG 1868
Query: 314 GANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G +A GY RF +P + Q RLYRTGDF L G + + GR D QVKI
Sbjct: 1869 GTGVAKGYWRDPEQTSLRFPVHPGSGQ----RLYRTGDFARHLPDGTLEFLGRQDDQVKI 1924
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
G RV+L EVE AL ++P V V+ G RG+ ++GF A + +L
Sbjct: 1925 GGFRVELGEVEAALGRLPDVAAGAVIATGDPRGDRRLVGFAVPAREGGFDAAGLRRQLAR 1984
Query: 431 ALTHYMMP-QVIEVESIPLLVNGKVDRQGLLKM 462
L YM+P ++ ++ +PL NGKVDR L ++
Sbjct: 1985 RLPAYMVPTTLLPLDRLPLTANGKVDRAALQRL 2017
>UniRef50_A7BXM0 Cluster: Non-ribosomal peptide synthetase; n=2;
Beggiatoa|Rep: Non-ribosomal peptide synthetase -
Beggiatoa sp. PS
Length = 662
Score = 188 bits (457), Expect = 7e-46
Identities = 119/368 (32%), Positives = 187/368 (50%), Gaps = 15/368 (4%)
Query: 99 LAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSEEICVWKTALTF 158
++ + +++A V+YTSGSTG PKG ++ ICNRL+W + + ++ + + KT +F
Sbjct: 35 VSSIKPENLAYVIYTSGSTGKPKGAMNTHFGICNRLFWMQDAYSLTTTDSV-LQKTPFSF 93
Query: 159 VDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERLVLVPTLLRSILMYLALGPASR 216
SV E + PL G L++ E +D L+ IE+ + + S+L
Sbjct: 94 DVSVWEFFWPLFAGARLVVAKPEGHKDSAYLIKTIIEQQITTLHFVPSMLQVFLQESEVE 153
Query: 217 PLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLD 276
LK +CSGE LS E +F +L N YG TE DVTY+ + + QL+
Sbjct: 154 KCTSLKRVICSGEALSLERQEQFLA----RSQAQLHNLYGPTEAAVDVTYWPCQRNSQLN 209
Query: 277 LYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGG--ANRFCDNP 334
++PIGRP+ N IY++D + P GE+++ G +A GY+ A F NP
Sbjct: 210 ---SVPIGRPIANTQIYIVDHDYQPVPIGVIGELYIGGDGVARGYLNRPDLTAETFIPNP 266
Query: 335 HATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKC 393
+ LY+TGD L +G + Y GR D QV+IRG RV+L E+E+ L Q P V +
Sbjct: 267 FNQDGKNGPLYKTGDLARYLPEGNIEYLGRIDNQVQIRGFRVELGEIEKVLTQHPAVRES 326
Query: 394 VVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLRSALTHYMMPQ-VIEVESIPLLVN 451
VV+ N ++ ++ + + + L YM+P +++E+IPL N
Sbjct: 327 VVIVKEEPEQNQRLIAYIIPVASEDKIDISELRRFIAETLPDYMVPSFFVKMETIPLTPN 386
Query: 452 GKVDRQGL 459
GK+DR+ L
Sbjct: 387 GKIDRRAL 394
>UniRef50_Q0LIS9 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1816
Score = 187 bits (456), Expect = 9e-46
Identities = 165/559 (29%), Positives = 254/559 (45%), Gaps = 47/559 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ L KAGAAYVP++P +PQ RI+ +L+D SL++ + E +P E
Sbjct: 566 LVGALGILKAGAAYVPIDPIYPQDRISAMLEDGAVSLLL----THAELAAE--LPKLDLE 619
Query: 80 ELA-QEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
L +A A P LA L S+ VL+TSGSTG PKGV + + N +
Sbjct: 620 VLCLDQAWPTIAQAPTHNLNLA-LEPRSLMYVLFTSGSTGRPKGVAIEHHNYVNYIQGLL 678
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NI 192
+ D + T + + ++G L G L I++ E DP+ I
Sbjct: 679 QRIEAEDGWSYALVSTFAADLGTT-NVYGALCSGGELHIVAYERATDPEAFAAYFRQHRI 737
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+ + LVP+ ++ L P +RL + +GE E S+ + + +L
Sbjct: 738 DVMKLVPSHFEAMRGLNNLADVI-PKQRL---ILAGEASLWEQLSDIRQL---QPSVQLQ 790
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYP--TIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
N YG TE + Y + YP T+P+GRPL N IY+LD + PT PGE+
Sbjct: 791 NHYGPTETTVSMLTYPIPSQPH---YPSSTVPLGRPLGNVQIYVLDRRMQPTPQGVPGEL 847
Query: 311 WVAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQ 367
+V GA + GY+G A RF NP +T+ RLYR+GD GA+ + GR D Q
Sbjct: 848 YVGGAGVGRGYIGRPDLTAERFVPNPFSTEAG-ARLYRSGDLVRYQPDGAIEFLGRIDLQ 906
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VKIRG+RV+L E+E A+ V VV+ G+ ++ ++ + G + I
Sbjct: 907 VKIRGYRVELSEIETAIQAQAQVANSVVILREDTPGDKRLVAYIVPEAGQSLNIGSIREA 966
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXX 486
LR++L YM+P +E++ +PL NGK++R+ L + N D+ VA
Sbjct: 967 LRNSLPDYMVPTAFVELDGLPLNPNGKIERRAL--PAPSNERNLDSYVAPQ--------- 1015
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
VLG G + F++LGG S +I + K+ + + +
Sbjct: 1016 -TATEHELAGIWAEVLGLDQVG---IDDNFFDLGGESFKAIRVVRKIGSHISVMTLFKYP 1071
Query: 547 GASTLGEVLSKMSTDPNGG 565
L LS S+ +GG
Sbjct: 1072 TVRELAAHLSGASSAESGG 1090
>UniRef50_Q9Z5F4 Cluster: Ta1; n=4; Bacteria|Rep: Ta1 - Myxococcus
xanthus
Length = 2393
Score = 187 bits (455), Expect = 1e-45
Identities = 143/447 (31%), Positives = 214/447 (47%), Gaps = 33/447 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A+L AGAAYVP++P P+ R+ ++L+D+ +V+ + S K + + AS +
Sbjct: 492 VAAMLGVLSAGAAYVPLDPVHPEDRLRYMLEDSGVVVVL---ARQASRDKVAAIAGASCK 548
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E A A + + +A V+YTSGSTG PKGV + + + N L R
Sbjct: 549 VCVLEDVKAGA-----TSAPAGTSPNGLAYVIYTSGSTGRPKGVMIPHRGVVNFLLCMRR 603
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T ++ + T F + E+ PL G ++I S ET RD Q L R P
Sbjct: 604 TLGLKRTDSLLA-VTTYCFDIAALELLLPLCAGAQVIIASAETVRDAQALKRALRTHR-P 661
Query: 200 TLLRSI--LMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL+++ L R+++ +C GE L + L + F + + + N +G
Sbjct: 662 TLMQATPATWTLLFQSGWENAERVRI-LCGGEALPESLKAHFVRTASD-----VWNMFGP 715
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T + S + IG+P+DN +Y+LD+ + P PGE+W+AGA +
Sbjct: 716 TETTIWSTMAKVSASRP------VTIGKPIDNTQVYVLDDRMQPVPIGVPGELWIAGAGV 769
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF NP LYRTGD G V Y GR D QVK+RG R
Sbjct: 770 ACGYLNRPALTAERFVSNPFTPG---TTLYRTGDLARWRADGEVEYLGRLDHQVKVRGFR 826
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
+++ E+E LA P V C V+ L+ G +++ + G + I LR L
Sbjct: 827 IEMGEIEAQLAGHPSVKNCAVVAKELN-GTSQLVAY-CQPAGTSFDEEAIRAHLRKFLPD 884
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGLL 460
YM+P V V++IPL NGKVDR L+
Sbjct: 885 YMVPAHVFAVDAIPLSGNGKVDRGQLM 911
>UniRef50_Q0K0K6 Cluster: Non-ribosomal peptide synthetase modules
and related proteins precursor; n=1; Ralstonia eutropha
H16|Rep: Non-ribosomal peptide synthetase modules and
related proteins precursor - Ralstonia eutropha (strain
ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus
necator (strain ATCC 17699 / H16 / DSM 428 /
Stanier337))
Length = 1075
Score = 187 bits (455), Expect = 1e-45
Identities = 145/449 (32%), Positives = 208/449 (46%), Gaps = 24/449 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ LL KAGAAY+P++ P R HIL A L++ +A + +SG
Sbjct: 538 VAVLLGILKAGAAYLPVDAHHPAARNAHILGHARARLILAS-AATRAALGDSGAVV---- 592
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L T + P D AP +A LYTSGSTG PKGV++S A N L
Sbjct: 593 -LVDGDTPPWSTAP-DTPPAAPCHPAQLAYTLYTSGSTGTPKGVQISRGAFANFLRAMTP 650
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P S+ + T L F + E++ PL G ++I +R+ RDP +L + +
Sbjct: 651 VVPMDGSDRLLA-VTTLGFDIAGLELFLPLASGARVVIATRDDARDPARLAALMSAHGIT 709
Query: 200 TLLRSILMY-LALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+ + + + + AS P L++ +C GE L +ELA+ G ++ N YG T
Sbjct: 710 VMQATPATWQMLVTQASPPWEGLRV-LCGGEALGRELATALLAR-----GAQVCNVYGPT 763
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + L ++ + P+GRP+ N +Y+LD L P GE+++ GA LA
Sbjct: 764 ETTVWSAAHAL-AAEGAPAWAVAPVGRPIANNQLYVLDARLEPVPPGVAGELYIGGAGLA 822
Query: 319 AGYVGGGG--ANRFCDNPHATQPEF----QRLYRTGDFGTL-VKGAVLYAGRTDAQVKIR 371
GY A F NP A RLYRTGD V G V + GR D QVK+R
Sbjct: 823 RGYAEDPARTAAAFVPNPFAPGTPGAMAGDRLYRTGDLARKRVDGIVEFLGRRDHQVKVR 882
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSA 431
G RV+ EVE AL+ P V + V + G + + S I +LR
Sbjct: 883 GFRVEPGEVEAALSACPQVSQAVCVARQGPDGMARLCAYYVAATAGDDSDDAILARLREQ 942
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L YM+P + ++++PL NGKVDRQ L
Sbjct: 943 LPGYMVPSSLTRLDALPLNANGKVDRQAL 971
>UniRef50_A5FI40 Cluster: Amino acid adenylation domain; n=1;
Flavobacterium johnsoniae UW101|Rep: Amino acid
adenylation domain - Flavobacterium johnsoniae UW101
Length = 1992
Score = 187 bits (455), Expect = 1e-45
Identities = 164/559 (29%), Positives = 270/559 (48%), Gaps = 48/559 (8%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+I+++L KAG YVP++ P R +I +DA+ L+I + + + G F+
Sbjct: 597 SIVSILGILKAGGVYVPIDTELPSNRKLYIAQDADLKLLITETAFIFDLDFYQGDIFSID 656
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
EL T+ + D L +A V+YTSGSTG PKGV + +S + N Q
Sbjct: 657 VELD---TNPEENIYQDVNLLPA----DLAYVIYTSGSTGNPKGVMIKHSGLINTAVSQI 709
Query: 139 RTF-PYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN--IERL 195
F PY+ S + ++ +F S+ EI+ LL G +L IL+ ET +D + + +E
Sbjct: 710 ELFKPYNCSNWLQY--SSHSFDASIYEIFISLLGGHSLFILNEETRKDVKLFESYVVENN 767
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ + L + L + + L+ K+ + GE+ + +EF ++ GN N Y
Sbjct: 768 IDISILPPAFFKMLDV----QSLKGFKVLITGGESAVYDKVAEFVQH-GN-----FFNAY 817
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TEV T +E +L L T+PIG+P+ N +Y+LDE L+ + GE+++ GA
Sbjct: 818 GPTEVCVLGTISKIEKGSEL-LSKTVPIGKPIANTEVYILDEYLNLLPEGAIGEIYITGA 876
Query: 316 NLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
LA GY+ A +F NP+ E + +Y+TGD G L G + Y GR D QVKIRG
Sbjct: 877 GLARGYLNRPELTAEKFIPNPY---KEGEIMYKTGDLGKWLADGNIEYTGRIDEQVKIRG 933
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
+R++L E+E+ L+ V VV+ ++ + ++ + + + ++ L L
Sbjct: 934 YRIELEEIEKHLSLQDEVKHAVVVVKE-NQDDKYLVAYYVS--DVELDKRKLQAALGKIL 990
Query: 433 THYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P ++VESI + +GKVDR+ L + E+ D+
Sbjct: 991 PEYMIPGYFVQVESILMNTSGKVDRKALPDVVES-----------DLIKEEYIAPRTSEE 1039
Query: 492 XXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTL 551
VL G ++ F+ LGG+S+ SI I++L+ +GY +++ L L
Sbjct: 1040 KLLAAAWSEVLKYEKIG---VKDSFFNLGGDSIKSIMLISRLKQQGYVIKVEQILRQPVL 1096
Query: 552 GEVLSKMSTDPNGGADSKE 570
E L+K+ D KE
Sbjct: 1097 -EDLAKLVEINTIAVDQKE 1114
>UniRef50_A3YGJ0 Cluster: Amino acid adenylation; n=1; Marinomonas sp.
MED121|Rep: Amino acid adenylation - Marinomonas sp.
MED121
Length = 3256
Score = 187 bits (455), Expect = 1e-45
Identities = 160/561 (28%), Positives = 259/561 (46%), Gaps = 43/561 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA KAGAAYVP++P+ P+ R++ I + + +L + D S F+ V +
Sbjct: 1862 LVALLAIQKAGAAYVPLDPAQPKARLSMIAERSGATLCLCD-STTIQTFEALEVESLTPV 1920
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L S ++ + + P S+A LYTSGSTG+PKGV+L N L R
Sbjct: 1921 NLGSLTEELSTQSNLNTKLVVP--EQSLAYTLYTSGSTGVPKGVQLERRQFANFLRAMER 1978
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P + + T +TF + E++ PL++G A+++ + RD +++ + + +
Sbjct: 1979 VLPPFNK---VLALTTITFDIAGLELFLPLVNGAAVILADEDARRDGEQIGRLIQEHDID 2035
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + + L S + + GE L ELAS+ + + L N YG TE
Sbjct: 2036 LIQATPSGWRLLDELSDDALSNVVALAGGEALDSELASKLKRQCRD-----LINVYGPTE 2090
Query: 260 V-MGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
+ +Y V E S P PIG PL N +++LD +L P GE+++AG +A
Sbjct: 2091 TTVWSSSYLVQETS-----LPLTPIGTPLLNNDLHVLDAQLQPVPQGVIGELYIAGEGVA 2145
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDF-GTLVKGAVLYAGRTDAQVKIRGHRV 375
GY G A RF NP + RLYRTGD L G + + GR D QVK+RG R+
Sbjct: 2146 RGYQGQADLTAERFLPNPFG---DGNRLYRTGDLVKHLADGTLYFVGRVDQQVKLRGFRI 2202
Query: 376 DLLEVERALAQVPGV---------DKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
+L ++E AL P + ++ + C + P + + + + ++
Sbjct: 2203 ELGDIEAALLANPNIKQAAVTIEKERLIAWCVAVPTSEPSSESDSHSAFESSETIKKLQA 2262
Query: 427 KLRSALTHYMMPQVIE-VESIPLLVNGKVDRQGLLK-------MYENTNNNDDAEVAVDI 478
+L L YM+PQ E + S+PL +GKVDR L K +NT+ + EV+VD
Sbjct: 2263 ELALILPEYMLPQGYEWLSSLPLNASGKVDRNALSKRELSAAFSSQNTSQSGFNEVSVDA 2322
Query: 479 DCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGY 538
A+L T++ + F+ LGG+SL + ++LR +G+
Sbjct: 2323 LEGQAEQVLTQYEVIVSDIWKALLNLE---TVNKQDHFFNLGGHSLMAAQVRSRLRAQGF 2379
Query: 539 YVEISDFLGASTLGEVLSKMS 559
V + L E+ +S
Sbjct: 2380 DVSLKTLFETPVLSELAKHLS 2400
Score = 79.0 bits (186), Expect = 5e-13
Identities = 123/500 (24%), Positives = 206/500 (41%), Gaps = 74/500 (14%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKE--------- 70
I +LLA W+ GA + ++P P+ R+ +++++ SLV++ + + E
Sbjct: 595 IASLLACWRIGAIALMLDPRQPEQRLKDLVEESNTSLVLHTFLPSDASYTEHTERLLNIE 654
Query: 71 -------SGVPFASFEELAQEATSHSADEPMDAETLAP--LTSDSIAIVLYTSGSTGIPK 121
S + S+ +L E ++++A + S+ IA +LYTSGSTG PK
Sbjct: 655 NGQSEGVSSISLTSWNDLLAFELPIQDLEGKASKSIASEDIASEDIAYILYTSGSTGKPK 714
Query: 122 GVRLSYSAICNRLWWQFRTFPYSDSEEICVWKTALTFVDSV--CEIWGPLLHGRALLILS 179
GV +S+ A+ + + P S E W T T + + L G+ LL+
Sbjct: 715 GVLVSHGALAHYSAAISQAIP---SVEGGRWLTLATVAADLGLTSVLAALYQGQTLLLPE 771
Query: 180 RETTRDPQKLVNIER------LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSK 233
E +P +L + R L +VP+ L+ L+ ++ P R L + GE + +
Sbjct: 772 AELAFNPPELADFLRQHPTDYLKIVPSHLKG-LLSVSSPIDILPKRAL---ISGGEGMDE 827
Query: 234 ELASEFFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEG--SDQLDLYPTI-PIGRPLDNC 290
L ++ + N YG +E V+ L +D + + P+GR L
Sbjct: 828 ALLNQLHSL---SPDMAIFNHYGPSESTVGVSVIELNNQITDSFEGMSLVAPLGRALPES 884
Query: 291 AIYLLDEE--LSPT---------------------RDSEPGEVWVAGANLAAGYVGGGGA 327
+ + E L P D +V +L A +V +
Sbjct: 885 CLEIRAENGVLLPQGAMGELCISGPQLANGYFIKGHDQGDTKVQATAKDLNAVFVESAVS 944
Query: 328 NRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRGHRVDLLEVERALAQ 386
+ + QR YRTGD L +G Y GR D Q+K RG+R++L EV L
Sbjct: 945 SSESIASSSKSATNQRYYRTGDRARLNNQGVFEYLGRLDDQIKRRGYRLELGEVSAWLQA 1004
Query: 387 VPGVDKCVVLCYGLDRGNPEILGFV------TTKPGARTS--AQHIEGKLRSALTHYMMP 438
V L L+R +L T P S A + ++++A+ YM+P
Sbjct: 1005 QAEVSLASALV--LERNERSLLVAAIELENPDTDPAINESKIASELLVRMKAAMPDYMVP 1062
Query: 439 -QVIEVESIPLLVNGKVDRQ 457
++ V+ + L NGK+DRQ
Sbjct: 1063 DNLVCVDKMALNTNGKIDRQ 1082
>UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9;
Bacteria|Rep: Putative polyketide synthase pksJ -
Bacillus subtilis
Length = 5045
Score = 187 bits (455), Expect = 1e-45
Identities = 141/445 (31%), Positives = 226/445 (50%), Gaps = 28/445 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AYVP++PS+P R+ ++L+D+E + + S + +GV A +
Sbjct: 1220 LVGLLAILKAGGAYVPLDPSYPAERLEYMLEDSEVFITL-TTSELVNTLSWNGVTTALLD 1278
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ E ++D + T+ P +++A V+YTSGSTG PKGV + + A+ N L
Sbjct: 1279 QDWDEIAQTASDRKVLTRTVTP---ENLAYVIYTSGSTGKPKGVMIPHKALTNFLVSMGE 1335
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T P +E+ + T F + E++ PL+ G I E T+D +KL R +
Sbjct: 1336 T-PGLTAEDKMLAVTTYCFDIAALELFLPLIKGAHCYICQTEHTKDVEKLKRDIRAIKPT 1394
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
+ + + L + +C GE L + L F + G + N +G TE
Sbjct: 1395 VMQATPATWKMLFYSGWENEESVKILCGGEALPETLKRYFL-----DTGSEAWNMFGPTE 1449
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
+ ++ + + TI GRP+ N IY+ D +L+P PGE+ +AG +A
Sbjct: 1450 T---TIWSAVQRINVECSHATI--GRPIANTQIYITDSQLAPVPAGVPGELCIAGDGVAK 1504
Query: 320 GYVGGGGA--NRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY +RF DNP +P +LYRTGD L G + Y GR D QVKIRG R++
Sbjct: 1505 GYYKKEELTDSRFIDNPF--EPG-SKLYRTGDMARWLTGGRIEYIGRIDNQVKIRGFRIE 1561
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK-PGARTSAQHIEGKLRSALTHY 435
L ++E L++ PG+ +CVV+ D N + + T K A +A+ + +++AL Y
Sbjct: 1562 LGDIESRLSEHPGILECVVVA---DMDN--LAAYYTAKHANASLTARELRHFVKNALPAY 1616
Query: 436 MMPQ-VIEVESIPLLVNGKVDRQGL 459
M+P I+++ +PL NGK+DR L
Sbjct: 1617 MVPSYFIQLDHMPLTPNGKIDRNSL 1641
Score = 41.5 bits (93), Expect = 0.084
Identities = 43/200 (21%), Positives = 81/200 (40%), Gaps = 28/200 (14%)
Query: 281 IPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPE 340
+ IG P+ ++ ++++ + E G V+G ++ +GY P +
Sbjct: 374 VEIGSPIPGFSMRIVNDHNELVEEGEIGRFQVSGLSVTSGYY---------QRPDLNESV 424
Query: 341 FQR--LYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCY 398
F + TGD G L G + GRT + I G +E A+ ++P ++
Sbjct: 425 FTEDGWFETGDLGFLRNGRLTITGRTKDAIIINGINYYSHAIESAVEELPEIETSYTAAC 484
Query: 399 GLDRG---NPEILGFVTTKPGARTSAQHIEGKLRSALTH----------YMMPQVIEVES 445
+ G ++ F T A+ + + + LR+ +H Y++P ++ E
Sbjct: 485 AVRLGQNSTDQLAIFFVT--SAKLNDEQMSQLLRNIQSHVSQVIGVTPEYLLP--VQKEE 540
Query: 446 IPLLVNGKVDRQGLLKMYEN 465
IP GK+ R L +EN
Sbjct: 541 IPKTAIGKIQRTQLKTSFEN 560
>UniRef50_Q1IA18 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Pseudomonas entomophila L48|Rep: Putative
non-ribosomal peptide synthetase - Pseudomonas
entomophila (strain L48)
Length = 2990
Score = 186 bits (454), Expect = 2e-45
Identities = 140/450 (31%), Positives = 217/450 (48%), Gaps = 26/450 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA KAG AYVP++P +P+ R+ H+L D+ P++++ A ++ S P
Sbjct: 96 LVAVLAVLKAGGAYVPLDPGYPRARLAHMLADSAPAVLLSHGPARAALDGLSLPPGVLDL 155
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + A +P D + + LT +A V+YTSGSTG PKGV + + + R
Sbjct: 156 DDSVAWADRPAHDP-DPQAIG-LTPRHLAYVIYTSGSTGTPKGVMVEHRGLVALSAAWAR 213
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLV- 196
+P + +F ++ L G L++ R+T DP L + E V
Sbjct: 214 LYPLQAPLNH-LQMAGFSFDVFSADLIRALGFGGTLVLCPRDTLMDPPALYRLLCEAEVG 272
Query: 197 ---LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VP +L +L + R L L+ VC + + A + + G ++
Sbjct: 273 FGDFVPAVLNPLLDWAEAN--GRDLSFLRTVVCGSDVWTAHSARQLRRLCGER--VQVVQ 328
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE D T + + +PIGRPL NC +YL D + + SE GEV++
Sbjct: 329 AYGVTEASIDSTCHEVPAEVAEG---ALPIGRPLANCRVYLFDAQ---GQASEEGEVYLG 382
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G +A GY+ A RF DNP +RLYRTGD L G + + GR D Q K+
Sbjct: 383 GVGVARGYLNLPHLTAERFVDNPFVAG---ERLYRTGDLARLRADGQLEFLGRNDHQAKL 439
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
RG R++L E+E LA+VPGV + +V G P ++ + GA + + +LR
Sbjct: 440 RGLRLELGEIEARLAEVPGVRESLVQLRQDTPGEPRLVAYYARHEGAALTPAELSRQLRM 499
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L YM+P +++ ++PL NGK DR GL
Sbjct: 500 HLPDYMVPSAFVQLPALPLTANGKYDRNGL 529
Score = 186 bits (454), Expect = 2e-45
Identities = 170/571 (29%), Positives = 259/571 (45%), Gaps = 51/571 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP +P++P R+ +L DA PSL++ S P G+P A
Sbjct: 1156 VVGLLAILKAGAAYVPFDPAYPAERLAFMLTDAAPSLLLTQASLRP------GLPPAVEL 1209
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ AD P + + + + + VLYTSGSTG PKGV S A+ N + WQ
Sbjct: 1210 LCLDSDAARWADCPGN-DPQVTVNPEHLGYVLYTSGSTGRPKGVAHSRRALDNLIAWQLD 1268
Query: 140 TFPYSDSEEIC--VWKTALTFVDSVCEIWGPLLHGRALLILSRETTRD-----PQKLVNI 192
P +C + +L F S EI L G L ++S +D P +
Sbjct: 1269 ETPM-----VCRVLQFASLNFDVSFQEICSTLCQGGTLQLMSEAGRKDLATLRPTLVAQG 1323
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLS-KELASEFFKYFGNEDGYKL 251
+P + L + A P ++ V +GE L + F + G G +L
Sbjct: 1324 VGRAFLPFAVLQQLAAVTEPDAPTPPAGCEI-VTAGEALQVNDALRAFVRGLG---GTRL 1379
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE V+ + L+ +D PIG+P+ N +Y+LD +L+P PGE++
Sbjct: 1380 CNQYGPTETHV-VSQFSLDCADAGHWPELPPIGKPIANARLYVLDGDLNPQPVGVPGELY 1438
Query: 312 VAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
+AG LA GY+ A RF +P + P R+YR+GD L G V Y GR D QV
Sbjct: 1439 IAGHCLARGYLNRAPLSAERFLPDPFSPAPG-ARMYRSGDLALLQADGNVQYLGRVDQQV 1497
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
K+RG R++L E++ L Q PGV VL G+P ++ +V AQ + L
Sbjct: 1498 KLRGFRIELGEIDSLLRQQPGVQDVAVLLREDVAGDPRLVAYVV----GTGDAQTLRAAL 1553
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
+ L +M+P + + +PL NGK+DRQ L D E D
Sbjct: 1554 QRQLPEHMLPTAWVSLAQLPLTRNGKLDRQAL--PAPERGGMADYEAPRD---------- 1601
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFL 546
V A + + R + +R F++LGG+SL + + + R G + +S
Sbjct: 1602 --ETERRMAQVWAEVLKCER--VGIRDNFFDLGGHSLLATRLVYAINQRLGAQLSLSSLF 1657
Query: 547 GASTLGEVLSKMSTDPNGGADSKEATFTAVP 577
A L ++ ++++ G A+ + A P
Sbjct: 1658 QAPVLMDLAAQVTVLEEGQAEPQLQALQADP 1688
Score = 165 bits (400), Expect = 5e-39
Identities = 141/450 (31%), Positives = 212/450 (47%), Gaps = 30/450 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA AG AY+P++P+ P R+ HIL+ AE +L + P + P A
Sbjct: 2210 VVATLAILYAGGAYLPIDPNLPATRLRHILERAEATLAL----TQPCLLGRVAWP-AQVT 2264
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
LA S EP+ + P D +A V+YTSGSTG PKGV + + N L R
Sbjct: 2265 ALAVTEQPGSQVEPLRDVQVGP---DDLAYVIYTSGSTGTPKGVVIDHQGAVNTLLDINR 2321
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIERLV 196
F + + ++L+F SV + +G L G A+++L + + DP +L+ ++
Sbjct: 2322 RFAVGPQDRVLAI-SSLSFDLSVYDFFGTLATGAAVVMLEPQLSLDPAHWAELIERHQVS 2380
Query: 197 L---VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VP LL + YL G L+L + SG+ + L + + G +L +
Sbjct: 2381 LWNSVPALLGMLAEYLE-GEGRVLPTSLRLAMLSGDWIPLALPE---RAWALRPGLQLMS 2436
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
G+TE Y + D + +IP G+ LD+ ++LD+ L G +++
Sbjct: 2437 LGGATEASIWSIGYPITQVDPA--WRSIPYGQALDHQRFHVLDDALQVRPTWVTGHLYIG 2494
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY A F D+P + RLYRTGD G L G + + GR D QVK+
Sbjct: 2495 GIGLAKGYWRDPALSARSFFDHPLTGE----RLYRTGDLGRRLPDGNIEFLGRDDNQVKV 2550
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
+G+R++L E+E L + PGV VV G + + G+V K A L
Sbjct: 2551 QGYRIELGEIETVLNRHPGVHSAVVRILGEAQAQKRLAGYV-LKADPALQAGDFNSYLAD 2609
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGL 459
L YM+P VE+ PL NGKVD+ L
Sbjct: 2610 KLPAYMVPSSFTFVEAWPLSANGKVDKSRL 2639
>UniRef50_A4KVL5 Cluster: Non-ribosomal peptide synthetase modules;
n=1; Sinorhizobium meliloti|Rep: Non-ribosomal peptide
synthetase modules - Rhizobium meliloti (Sinorhizobium
meliloti)
Length = 1112
Score = 186 bits (454), Expect = 2e-45
Identities = 154/561 (27%), Positives = 260/561 (46%), Gaps = 50/561 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+++LLA WKAGAA++P++PS+P R+ +L DA +++ DS + G +
Sbjct: 570 LISLLAVWKAGAAFLPLDPSYPSERVAFMLADANVGIILTQDSLRDRLPPFPGTIWCLGH 629
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E ++ A S +P+ P+ DS+A ++YTSGSTG PKGV + + CN +
Sbjct: 630 EWSRIAELPS--QPLQT----PVNPDSLAYIIYTSGSTGWPKGVMVPHRCACNTMQTIVD 683
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLI------LSRETTRDPQKLVNIE 193
+ + + L+F S+ ++ L G L + L + D + + I
Sbjct: 684 ALQLPVGARVLQFGS-LSFDISIYDLLMTLGCGGTLCLAPTNDLLPGQPLADTLRELRIN 742
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ L P+ L +I P + L L + GE L+ ELA + + ++ N
Sbjct: 743 AVALPPSALNAI-------PTTDDLPDLHTIMSGGEALAAELAQRW-----STPTCRVIN 790
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE TYY G + + +PIGR + Y+LD P PGE++V
Sbjct: 791 GYGPTEATIWSTYYQCSGDEDV-----LPIGRAVSQTQAYVLDRSAEPLPYGFPGELYVG 845
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKI 370
GA + GY+ G A ++ +P + +P RLYRTGD +L G + + GR D Q+K+
Sbjct: 846 GAGVTRGYMNRSGLTAEQYIPDPFSGEPG-SRLYRTGDRASLQSDGNIRFLGRIDNQIKL 904
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
G+R++L E+E AL + P V + V+ G + F T A T + + LR
Sbjct: 905 NGYRIELQEIESALTRHPQVTEAAVVVQRSRCGVSRLAAFCTVSGDAATIHKELLLYLRR 964
Query: 431 ALTHYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L YM+P+V + E +P+ +GK+DRQ L + + ++ E+A
Sbjct: 965 HLPKYMVPEVFTILEELPVNASGKLDRQKLSE-WTTPEFDEPREIA----------RATE 1013
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYY-VEISDFLGA 548
+LG +S F+ELGG+SL +I I +L + + + I D
Sbjct: 1014 PGEKVAQIFAEILG---VDRVSPSDSFFELGGHSLMAIRVIDRLNEAFLFSLTIRDLFEN 1070
Query: 549 STLGEVLSKMSTDPNGGADSK 569
+ +++ ++ G+ ++
Sbjct: 1071 PVVADLVRAVTLAQTAGSHAR 1091
>UniRef50_Q0LP29 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1553
Score = 186 bits (452), Expect = 3e-45
Identities = 157/550 (28%), Positives = 265/550 (48%), Gaps = 42/550 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+LA +KAG ++P++PSFP R+ +I+ DA+P LV+ +A + +P +
Sbjct: 565 VIAILAIFKAGGLFLPLDPSFPADRLAYIVADAKP-LVVLTTAA-----LAAELPLEAPH 618
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+A + H+ + +DA L ++A ++YTSG+TG PK V +++ + N L +
Sbjct: 619 IVALDQAWHAHIQQVDAPN-HQLQPSNLAYMIYTSGTTGTPKAVLVTHQNLLNVLLASQQ 677
Query: 140 TFPYSDSEEI-CVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP----QKLVNIER 194
F ++ + + C+ +F + E+ PLL G +L+RE D + L ++
Sbjct: 678 AFGFNPRDVMPCI--APFSFDIFLFELLNPLLAGGTSWMLTREEILDIAGLIESLASMSV 735
Query: 195 LVLVPTLLRSILMYLAL-GPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP+L+R ++ L G + + +++ G+ + EL + F + L
Sbjct: 736 IHTVPSLMRQLVNALETEGYTAAACQSIRMIFIGGDLVPPELLNAMRLAFPQAAIHVL-- 793
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T Y + L+ + IGRPL N AI L D + + PGE+++
Sbjct: 794 -YGPTEATIICTSYRVPQQGLLERHL---IGRPLPNMAIRLYDPQQNLVPIGMPGELYIG 849
Query: 314 GANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRG 372
GA ++ GY+ + D + QR YRTGD V G + + GR D QVKIRG
Sbjct: 850 GAGVSRGYLN---RSELTDEKFVELDQ-QRWYRTGDLARYQVDGNLEFLGRIDQQVKIRG 905
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
R++L E+E LAQ P + + VV+ G+ ++ ++ + + L++ L
Sbjct: 906 FRIELGEIEAVLAQHPSIREAVVVAREDLPGDKRLVAYLIAESEQMPHIGELRAFLQTKL 965
Query: 433 THYMMPQVIEV-ESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXX 491
YM+P V ES+PL NGKVDRQ L + T + + A +
Sbjct: 966 PEYMLPAAFMVLESLPLTRNGKVDRQA-LPVPPTTREHLANQFAAPTN----------QL 1014
Query: 492 XXXXXTVGA-VLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGAST 550
T+ A VLGR G + F+ELGG+S+ S+ + +L GY+V D T
Sbjct: 1015 ETLLSTIWAEVLGREQVG---IHDNFFELGGDSILSLQIVARLNQAGYHVLTKDIFQYQT 1071
Query: 551 LGEVLSKMST 560
+ E+ +S+
Sbjct: 1072 IAELAQVVSS 1081
>UniRef50_Q89T13 Cluster: Bll2237 protein; n=2; Bradyrhizobium|Rep:
Bll2237 protein - Bradyrhizobium japonicum
Length = 2154
Score = 185 bits (451), Expect = 4e-45
Identities = 141/468 (30%), Positives = 226/468 (48%), Gaps = 24/468 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ A++A + GAA++ ++P P R+ IL + + V+ A +M + P
Sbjct: 1150 LAAMIAVQRVGAAFLNLDPDQPPARLATIL-GSSCARVLLIGRAQSAMVEALLEPLVERI 1208
Query: 80 ELAQ--EATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
++A+ +A + A +P A A + S+A ++YTSGS+G PKGV + + N L
Sbjct: 1209 QVAELDDAIAPRATKPARAARRA---ASSLAYLIYTSGSSGAPKGVMIEQRGLSNHLASL 1265
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCE-IWGPLLHGRALLILSRETTRDPQKLVN-IER- 194
S + ++ +FV SV + + GP++ G + + +DP L IER
Sbjct: 1266 ISELKLS-ARDVIAQTAPQSFVISVWQFLAGPMV-GARVHVCGNAIVQDPILLAREIERE 1323
Query: 195 ----LVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYK 250
L +VP+LLR I+ + P R RL+L + +GE L +L +F
Sbjct: 1324 GITVLEIVPSLLRVIVDRMDEAPILRAFARLRLLISTGEPLPVDLCRA---WFARCPKVP 1380
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG++E DV+ + L +P+G PL N +Y+LD L P GE+
Sbjct: 1381 LINAYGASECSDDVSLHRLT-KPPATATSNVPVGAPLPNTQLYVLDANLEPQPVGVTGEL 1439
Query: 311 WVAGANLAAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFG-TLVKGAVLYAGRTDAQ 367
+ GA + GY+ N RF +P Q RLYRTGD G + GR D Q
Sbjct: 1440 CIGGAGVGRGYINDPAQNKQRFLPDPFLRQAA-SRLYRTGDLARRRADGTIECLGRADHQ 1498
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VK+RG+R++L E+E ALA P V +V G+ ++ + +PG+R SA +
Sbjct: 1499 VKVRGYRIELKEIENALADHPSVRAGIVEPRREASGDVRLIAHIVARPGSRVSASELRDF 1558
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEV 474
L+S L + +P + ++ +PL +GK+DR LL + + DA V
Sbjct: 1559 LKSRLPGHAIPSAFLFMDQVPLNAHGKIDRSMLLAPAQQEASEPDAAV 1606
Score = 58.0 bits (134), Expect = 9e-07
Identities = 64/280 (22%), Positives = 109/280 (38%), Gaps = 23/280 (8%)
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
VPT+ R++L P L++ + +L+ + FG + YG
Sbjct: 274 VPTIHRALLTAAEANPDRARASSLRVIRSASASLAPAILGGLEATFG----VPVLETYGM 329
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE + ++ +L +GR I ++DE GE+ + GAN+
Sbjct: 330 TEAASQIA------ANPFELRKLGSVGRAAGP-EIAVMDETGRALASGAHGEIVLRGANM 382
Query: 318 AAGYVGGGGANRFCDNPHATQPEFQR-LYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHRV 375
+ GY ++ ATQ F+ +RTGD G L G + GR + G ++
Sbjct: 383 SRGYY---------NDEAATQAAFRDGWFRTGDLGYLDADGYLFIVGRIKDVINRGGQKI 433
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
LEVE L P V + V + + V + + ++ + R L Y
Sbjct: 434 SPLEVEEVLLSHPAVLEAGVFAVPHPKLGENVAAVVVLRANSEATSDQLRKFARKRLAAY 493
Query: 436 MMPQVI-EVESIPLLVNGKVDRQGLLKMYENTNNNDDAEV 474
+P +I V ++P +GKV R L + + D A +
Sbjct: 494 KVPSLIRSVAALPKGASGKVKRNALADLIATAEDADAARL 533
>UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep:
Peptide synthetase - Anabaena circinalis 90
Length = 5060
Score = 185 bits (451), Expect = 4e-45
Identities = 130/400 (32%), Positives = 206/400 (51%), Gaps = 19/400 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LLA KAG AYVP++P +PQ R+ IL+DA+ S+++ + ++ +
Sbjct: 2687 IVGLLAILKAGGAYVPLDPDYPQERLNLILEDAQVSVLLIQQHLVEKL-QQHQAHIVCLD 2745
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ +S P++ T ++A V+YTSGSTG PKGV +++S + RL+
Sbjct: 2746 SDGEKIAQNSNSNPLNI-----ATPSNLAYVIYTSGSTGKPKGVLVNHSHVV-RLFAATD 2799
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
++ +S+++ + F SV E+WG LL+G L+++ TR P+ + V
Sbjct: 2800 SWYNFNSQDVWTMFHSYAFDFSVWEVWGALLYGGRLVVVGYLVTRSPKSFYELLCQEKVT 2859
Query: 200 TLLRSILMYLALGPASRPLR-----RLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
L ++ + L PA + + L+L + GETL +F G++ +L N
Sbjct: 2860 ILNQTPSAFRQLIPAEQSIATVGDLNLRLVIFGGETLELNSLQPWFDRHGDQSP-QLVNM 2918
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE VTY L +D L ++ IGRP+ + +Y+LDE L P GE++V G
Sbjct: 2919 YGITETTVHVTYRPLSKAD-LHGKASV-IGRPIGDLQVYVLDEHLQPVPIGVAGEMYVGG 2976
Query: 315 ANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIR 371
A + GY+ A RF NP E Q LY++GD L G + Y GR D QVKIR
Sbjct: 2977 AGVTRGYLNRAELTAQRFISNPFNGNSE-QLLYKSGDLARYLPNGELEYLGRIDNQVKIR 3035
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFV 411
G R++L E+E AL+Q+ V + VV+ N ++ +V
Sbjct: 3036 GFRIELGEIEAALSQLREVREVVVVARSDQPDNKRLVAYV 3075
Score = 167 bits (407), Expect = 8e-40
Identities = 138/456 (30%), Positives = 209/456 (45%), Gaps = 35/456 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSA-DPSMFKESGVPFASF 78
I+ LLA +KAG AYVP++P +PQ RI +LKD+ S+++ D E P+
Sbjct: 538 IVGLLAIFKAGGAYVPLDPEYPQKRIQFMLKDSGTSVLLTQSFLLDQLPIAEQQNPYQVI 597
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ +S D P T +++A V+YTSGSTG PKGV + + A+ N
Sbjct: 598 CLDQESFSSELTDNPNPQST-----PNNLAYVIYTSGSTGRPKGVMIEHQALVNLSLAWC 652
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
+TF + + + +F SV EI + G L + + ET Q LV+ +
Sbjct: 653 KTFQVQSQSRLLQFGS-FSFDLSVAEIATTYVSGACLYLPNIETLLPSQVLVDFLADHKI 711
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
S L A+ P L+ GE S EL + G + N YG T
Sbjct: 712 SHSFLSPSALSVLPQATLP--DLQYLSVGGEASSAELVERW------GTGRRFFNAYGPT 763
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T + + + + PIGRP+ N IY+LDE L PGE+ + GA LA
Sbjct: 764 ESTVAATIAICQPNGRKP-----PIGRPIANAQIYILDEYLQLVPVGVPGELHIGGAGLA 818
Query: 319 AGYVGGGGAN--RFCDNP-----------HATQPEFQRLYRTGDFGT-LVKGAVLYAGRT 364
GY+ +F NP +A + +LY+TGD L G + Y GR
Sbjct: 819 RGYLNRPELTQEKFIPNPFDNSKFKIPYRNAKDVQNSKLYKTGDLARYLPDGNIEYLGRI 878
Query: 365 DAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHI 424
D QVKIRG R++L E+E L+Q+ V V+ G+ ++ ++ + + +
Sbjct: 879 DNQVKIRGFRIELGEIEAVLSQLGDVQASCVIVREDITGDKRLVAYIVPQKEVTPTVTEL 938
Query: 425 EGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L++ L YM+P + +ES+PL NGK+D + L
Sbjct: 939 RQFLKAKLPEYMVPNAFVILESLPLTPNGKIDHRAL 974
Score = 146 bits (353), Expect = 3e-33
Identities = 117/382 (30%), Positives = 184/382 (48%), Gaps = 31/382 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAG AYVP++P +PQ R++ +L+D++ SL++ + + + P +
Sbjct: 4113 LVGILGILKAGGAYVPLDPEYPQERLSLMLEDSQVSLLLTQWTLIEKLPQHPAKP-VFLD 4171
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E+ Q+ +S + T A ++A V+YTSGSTG PKGV + + +CN Q +
Sbjct: 4172 EIWQQIAQNSQENLTGIVTAA-----NLANVIYTSGSTGKPKGVMVEHQGLCNLAQAQIQ 4226
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F I + +L+F + EI L G L + S+++ L+ R +
Sbjct: 4227 AFGLHSDSRILQF-ASLSFDACISEILMSLGSGGTLYLGSKDSLMPGTPLIERLRDYAIT 4285
Query: 200 --TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL S L L L L+ + +GE + EL ++ G N YG
Sbjct: 4286 HITLPPSALAVLH----KVELTTLQTIIVAGEACAVELIKQW------SAGRNFFNAYGP 4335
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE G V + + S L +P+ P+ N +Y+LD +L P PGE+ +AG +
Sbjct: 4336 TE--GSVCATLAKCSA---LTQKLPLVGPIANVQVYILDSQLQPVPIGVPGELHIAGVGV 4390
Query: 318 AAGYVGGGGAN--RFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY+ +F NP +LY+TGD G L G + Y GR D QVKIRG R
Sbjct: 4391 ARGYLNRPELTQEKFISNPFGPS----KLYKTGDLGRYLADGTIEYLGRIDNQVKIRGFR 4446
Query: 375 VDLLEVERALAQVPGVDKCVVL 396
++L E+E +Q P V + VV+
Sbjct: 4447 IELGEIEAVASQHPLVQESVVI 4468
Score = 136 bits (329), Expect = 2e-30
Identities = 129/475 (27%), Positives = 212/475 (44%), Gaps = 33/475 (6%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
S I+ LLA KAG YVP++P + Q R+ I +D++ S++I S+ GV
Sbjct: 1604 SIIVTLLAILKAGGGYVPLDPDYTQQRLADISEDSQFSVLITQQKLLNSL-PVQGVKIIV 1662
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+ ++ T+ S P ++ + +++A +LYTSGSTG PKGV L+++A+ N
Sbjct: 1663 LDTESEMLTNQSQVNP-----VSEVKPENLACLLYTSGSTGKPKGVMLTHAALVNHSSAI 1717
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VN 191
F + + + + + +F + EI+ G +++ + D L +
Sbjct: 1718 SEVFGLTSGDRVLQF-ASFSFDVAAEEIFPTWYKGATVVLRPTQMFPDFASLSQFIAQES 1776
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ L + P + ++ A+ P L+L G+ + E + + + G D
Sbjct: 1777 LSVLNITPAYWHEWAVAVSQDNATVP-PSLRLVAVGGDAVLLETVTIWRQVVG--DRVNC 1833
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE + L Q + ++ IGRP+ N Y+LD L P GE+
Sbjct: 1834 LNVYGPTEASVTAIVHDLL-HPQSETANSVLIGRPIANTQAYILDRHLQPVPVGVKGELH 1892
Query: 312 VAGANLAAGYVGGG--GANRFCDNP-----------HATQP-EFQRLYRTGDFGT-LVKG 356
+ G LA GY+ +F NP ++ P RLY+TGD L G
Sbjct: 1893 LCGVRLARGYLNRPELTEEKFIPNPFSGSRGAEILANSQSPVPSSRLYKTGDLARYLPDG 1952
Query: 357 AVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPG 416
+ GR D QVKIRG R++L E+E L Q V V+ G+ ++ +V P
Sbjct: 1953 NIECFGRIDNQVKIRGFRIELGEIEAVLNQYIDVQTSCVIIREDTPGDKYLVAYVVPYPE 2012
Query: 417 ARTSAQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNND 470
+ + L L YM+PQ + ++ +PL N KVDR+ L ++N D
Sbjct: 2013 KIPTISELRQFLSRNLPLYMVPQAFVFLDFLPLTPNRKVDRRALPAPDLSSNRTD 2067
>UniRef50_Q847C7 Cluster: NdaA; n=5; cellular organisms|Rep: NdaA -
Nodularia spumigena
Length = 2607
Score = 185 bits (451), Expect = 4e-45
Identities = 125/404 (30%), Positives = 207/404 (51%), Gaps = 20/404 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +L KAG AYVP++PS+P R+T+ L+DA +++ S PS+ + +
Sbjct: 312 VVGILGILKAGGAYVPLDPSYPAERLTYTLQDAAVPILLTQKSLLPSLPENQAIVMCLDR 371
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A + A+ ++A V+YTSGSTG PKGV +++ + RL+ +
Sbjct: 372 DWGVIAACSQENIVSHAQP------QNLAYVIYTSGSTGKPKGVLINHQNVI-RLFAATQ 424
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK---LVNIERLV 196
+ + + ++ ++ F SV E+WG LL+G +L+I+ +RDP L+ E++
Sbjct: 425 AWYHFGASDVFTLFHSIAFDFSVWELWGALLYGGSLVIVPYWVSRDPSAFHTLLRQEQVT 484
Query: 197 LV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
++ P+ R ++ L L+L + GE L + +F+ + ++ +L N
Sbjct: 485 VLNQTPSAFRQLIRVEELAKTGESQLSLRLVIFGGEALEPQSLQPWFEGYKDQSP-QLVN 543
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VTY L +D + I G P+ + +Y+LDE+L P GE+++
Sbjct: 544 MYGITETTVHVTYRPLSIADVNNSKSLI--GVPIPDLQLYILDEQLKPLPIGIKGEMYIG 601
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
GA LA GY+ A RF NP + PE RLY+TGD L G + Y R D QVKI
Sbjct: 602 GAGLARGYLNRPELTAERFIPNPFSDAPE-ARLYKTGDLARYLENGDIEYLDRIDNQVKI 660
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTK 414
RG R++L E+E AL + P V + VV+ G+ ++ ++ K
Sbjct: 661 RGFRIELGEIEAALLKYPEVQEAVVMARTDQPGDKRLVAYIVAK 704
Score = 145 bits (352), Expect = 3e-33
Identities = 144/559 (25%), Positives = 245/559 (43%), Gaps = 48/559 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVI----YDD---SADPSMFKESG 72
+ A+LA +KAG Y+P+ P+ R + ++ PS+V+ Y D S ++ K
Sbjct: 2061 VAAMLAVFKAGGIYLPLRLDEPEERYSRMMLKTSPSIVVTAAEYLDVVKSRLAALSKPPH 2120
Query: 73 VPFASFEELAQEAT-------SHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRL 125
+ + E+ Q S S E + +TL +D +++TSGSTG PK +
Sbjct: 2121 ILVITANEITQRYEWNGTNYQSFSVVESENPKTLLLPDADDSNYIMFTSGSTGEPKAILG 2180
Query: 126 SYSAICNRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRD 185
S+ ++ + + W+ F + + C+ + F + E L G L I D
Sbjct: 2181 SHGSLRHFINWEKIEFGINQNWR-CLQIAQINFDAYLRETLVTLCSGGTLYIPDSTDRED 2239
Query: 186 PQKLV------NIERLVLVPTLLRSILMYLA-LGPASRPLRRLKLWVCSGETLSKELASE 238
+ L+ I L VP+++R L L A + L+ L++ V GE L + E
Sbjct: 2240 LEGLLLRLGEWQINLLHTVPSVMRLFLKIGENLAHADQLLKNLQVLVLGGEPLFVKELCE 2299
Query: 239 FFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEE 298
+ K FG + + N YG++E +Y + ++ Y +P G+ L + A +++
Sbjct: 2300 WHKVFGEQTEF--VNIYGASETTFVKHFYRIPDPSKIT-YARVPAGKTLSDAAFAVINGT 2356
Query: 299 LSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTLVKGAV 358
P E GE++V L GY P+ +YRTGD G L+
Sbjct: 2357 -RPCAVGEVGEIFVKSPYLTKGYYQDQKLTNLVFVPNPLNNGSDLVYRTGDLGRLLPDMS 2415
Query: 359 L-YAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA 417
L GR+D Q+K+ G R++L E+E A+ + GV+K +V+ E++ + G
Sbjct: 2416 LEVVGRSDNQIKLNGVRIELGEIENAIYAIDGVEKTLVVA----EKKEELVTVIAYYQGN 2471
Query: 418 RTSAQH-IEGKLRSALTHYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVA 475
T+ Q I +++ L YM P ++ +E PLL NGK++R L K NT
Sbjct: 2472 DTANQEDIRRQIKQVLPIYMQPNFLMRLEYFPLLPNGKINRLALPKPEANT--------- 2522
Query: 476 VDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
S G +L +R F+ELGGNSL ++ ++++R+
Sbjct: 2523 --AQTSSQFTSFSEQEALLASVWGELL---VVEVSDIRQSFFELGGNSLKAMRLVSQIRN 2577
Query: 536 R-GYYVEISDFLGASTLGE 553
R G + + + +TL E
Sbjct: 2578 RFGISLRLREIFTHNTLEE 2596
Score = 43.6 bits (98), Expect = 0.021
Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 14/144 (9%)
Query: 418 RTSAQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAV 476
R + G L+ +L YM+P + +E++PL NGKVDR+ L A
Sbjct: 1118 RQLVPQLRGFLKQSLPDYMIPSAFVTLEALPLTSNGKVDRRAL-----------PAPQTA 1166
Query: 477 DIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR 536
D + A + R + + F+ LGG+S+ SI + ++R
Sbjct: 1167 RADLEKAFVAPRTLEEQVLADIWAEILSLER--VGIHDNFFALGGDSIRSIQVLALAKER 1224
Query: 537 GYYVEISDFLGASTLGEVLSKMST 560
G + + T+ E+ ++T
Sbjct: 1225 GLHFSVQQIFVHQTIYELTQNLAT 1248
>UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1;
Plesiocystis pacifica SIR-1|Rep: Non-ribosomal peptide
synthetase - Plesiocystis pacifica SIR-1
Length = 3382
Score = 185 bits (451), Expect = 4e-45
Identities = 139/445 (31%), Positives = 221/445 (49%), Gaps = 25/445 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL AGAAY+P++P +P+ R+ +L+D+ +L++ D + K P +S+
Sbjct: 460 VVGLLGVLMAGAAYLPLDPIYPEARLRTMLEDSGAALLLVDAFG---ISKPLAWPGSSWR 516
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A S + D+ AP T + +A ++YTSGSTG PKGV + + ++ N L Q
Sbjct: 517 AVELGACVLSGERASDSALPAP-TGEDLAYLIYTSGSTGRPKGVPIRHESLANLLA-QVA 574
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV-NIERLVLV 198
T P ++ + T + F ++ E++ PL G L++++ RD Q LV +E +
Sbjct: 575 TRPGFGPDDRMLAATTVCFDIAMLELFLPLTQGGELVLMTSAEARDGQALVAQLESGAVS 634
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
+AL R +++ +C GE L +LA L N YG T
Sbjct: 635 VAQATPATWRMALAAGWRERAPVRI-LCGGEALPADLAQALLSRCD-----ALWNMYGPT 688
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E + D++ + IGRPL + +Y+LD+EL+P PG++++ G L+
Sbjct: 689 EAT------IWASCDRVRATGPVTIGRPLGHYRLYILDDELAPVAPGLPGDLYIGGVALS 742
Query: 319 AGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRV 375
GY G A F NPH + + RLYRTGD L G V + R D QVKI G+RV
Sbjct: 743 PGYHGRPELDAKTFVANPHDPE-DAPRLYRTGDVARFLSDGRVEWLRRADDQVKILGYRV 801
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L E++ AL +PG+ + G P I+ +V + G+ A L L Y
Sbjct: 802 ELGEIDAALRALPGIADAAAVIREDSPGVPRIVAYV-VRSGSGDEASW-RAALGERLPSY 859
Query: 436 MMP-QVIEVESIPLLVNGKVDRQGL 459
M+P Q + +E++PL N KVDR+ L
Sbjct: 860 MIPRQFVAIEALPLSHNLKVDRKRL 884
Score = 127 bits (306), Expect = 1e-27
Identities = 139/533 (26%), Positives = 222/533 (41%), Gaps = 35/533 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA AGAAYVP++P+ P R+ HI++ E + + S D S+ G+ +
Sbjct: 1515 VVAALAVNVAGAAYVPIDPTMPAARLGHIVEFTEARVALTQSSLDASLSWPVGLVRVCVD 1574
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + P L +D +A V++TSGSTG PKGV L + N +
Sbjct: 1575 AMGDGRAFVERELPQ----LERQPTD-LAYVIFTSGSTGTPKGVMLDHRGPVNTILDVNA 1629
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F ++ ++L F SV +++G L G A+++ E RDP +L + V
Sbjct: 1630 RFEIGPADRTLA-VSSLGFDLSVYDLFGLLAVGGAVVVPEPEDLRDPLRLAELVEAHAV- 1687
Query: 200 TLLRSILMYLAL----GPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
T+ ++ Y L S LR L++ + SG+ + L + + +
Sbjct: 1688 TIWNTVPAYADLLEEAARGSAQLRSLRVVMMSGDWIPVGLPD---RLRAQCPAAAITSLG 1744
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPT-RDSEPGEVWVAG 314
G+TE Y ++ D + +IP G + L+DE+ P ++ + G
Sbjct: 1745 GATEASIWSILYPIDAVD--PSWKSIPYGAAMVAQPWCLIDEDGQVVDAVGVPAQLHIGG 1802
Query: 315 ANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
+A GY H E R+Y TGD G L G + GR D QVK+ G+
Sbjct: 1803 VGVALGYWRNPDKTGAAFIAHPETGE--RIYATGDRGQLRADGNYEFLGRIDRQVKLNGY 1860
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILG-FVTTKPGARTSAQHIE--GKLRS 430
R++L E+E L + GV + +VL G G LG FV + GA E +
Sbjct: 1861 RIELGEIEATLQRCEGVARALVLVLG--DGQARHLGAFVEAEAGAGAGPSEAELVALAKQ 1918
Query: 431 ALTHYMMPQVIE-VESIPLLVNGKVDRQGLLKMYENTN------NNDDAEVAVDIDCSXX 483
L YM P+ V + L NGKVDR+ + E + A A+ +
Sbjct: 1919 WLPTYMQPKTYACVRRLQLTANGKVDRRVSPEQLEAERVPFEGATSSPAPSALAPAPATP 1978
Query: 484 XXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR 536
+LG A G + +ELG SL + + ++R+R
Sbjct: 1979 SASPESVFAELAAVAAELLGAAVEGP---QVDLFELGATSLTIMRLVQRVRER 2028
>UniRef50_Q7D791 Cluster: Peptide synthetase; n=18; Mycobacterium|Rep:
Peptide synthetase - Mycobacterium tuberculosis
Length = 1787
Score = 185 bits (450), Expect = 5e-45
Identities = 160/558 (28%), Positives = 258/558 (46%), Gaps = 68/558 (12%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ L K+GA YVP++PS+PQ R+ IL D + LV+
Sbjct: 608 IVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLVLRTP------------------ 649
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+E + +D+P DA+ + PL D+ A ++YTSG+TG+PKGV + + + W
Sbjct: 650 --VRELAGYRSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKG 707
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLV------NIE 193
+ D++ + + + +F S+ EI+G L G ++I D L I
Sbjct: 708 EYDVDDTDRL-LQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGIT 766
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
+ VP+LL ++L+L P R L+ GE L E+A +F F D L N
Sbjct: 767 AMHFVPSLLG---LFLSL-PGVSQWRTLQRVPIGGEPLPGEVADKFHATF---DAL-LHN 818
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
FYG TE + + + + + G + +PIGRP N ++LLD+ L P GE+++
Sbjct: 819 FYGPTETVINASRFKVVGPQGTRI---VPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIG 875
Query: 314 GANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKI 370
G ++A GY G A RF +P P R+YR+GD G + + GR D QVKI
Sbjct: 876 GTHVAYGYHRRAGLTAERFVADPF--NPG-SRMYRSGDLARRNADGDIEFVGRADEQVKI 932
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSA------QHI 424
RG R++L +V A+A P V + VV+ L R ++G+VT G A I
Sbjct: 933 RGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRI 992
Query: 425 EGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXX 483
++ +AL YM+P + ++ IP+ +GK+DR L + ++A D +
Sbjct: 993 RARVAAALPEYMLPAAYVVLDEIPITAHGKIDRAAL----------PEPQIASDTE---F 1039
Query: 484 XXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEI 542
G +LGR G F++LGG+SL + + +R+ G V +
Sbjct: 1040 RAPQTATERRLAQLFGELLGRDRVGA---DDSFFDLGGHSLLATKLVAAVRNAFGVDVGV 1096
Query: 543 SDFLGASTLGEVLSKMST 560
+ +T+ + + T
Sbjct: 1097 REIFEFATVTALAGHIDT 1114
Score = 35.9 bits (79), Expect = 4.2
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 292 IYLLDEELSPTRDSEPGEVWVAGANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGD 349
+YLLD+ L P G+V+ G + A RF +P A QP RLYR G+
Sbjct: 1589 VYLLDDALKPVPVGVVGDVYYGGGPAVGARLARPSETATRFVADPFAAQPG-SRLYRNGE 1647
Query: 350 FG 351
G
Sbjct: 1648 RG 1649
>UniRef50_Q2XNF7 Cluster: L-alanine specific nonribosomal peptide
synthetase; n=1; Lysobacter lactamgenus|Rep: L-alanine
specific nonribosomal peptide synthetase - Lysobacter
lactamgenus
Length = 1056
Score = 185 bits (450), Expect = 5e-45
Identities = 151/454 (33%), Positives = 223/454 (49%), Gaps = 38/454 (8%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFEE 80
+ALLA K+G+AYVP++PS+P R+ HIL DA P+L I D+ ++ GV A +
Sbjct: 514 VALLAVLKSGSAYVPIDPSYPPARVRHILDDARPALAIVDEQGAAALGPFDGV--AIRID 571
Query: 81 LAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRT 140
A A A A L++ +A V+YTSGSTG PKGV + + + + W
Sbjct: 572 AAAGAGHDEAASANPARAATGLSAHDVAYVIYTSGSTGRPKGVLIEHRNAASFIQWALAH 631
Query: 141 FPYSDSEEICVWKTALTFVDSVCEIWGPL-LHGRALLILSRETTRDPQKLVNIERLVLVP 199
+P ++ + T++ F S+ E++ PL GR +L + RD + IE L L+
Sbjct: 632 YP-AEKLAAVLAATSICFDLSIFEMFVPLATGGRVVLAENVLALRDHE----IEGLSLIN 686
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
T+ +I L R +R + L +GE L +EL E + G + Y L YG +E
Sbjct: 687 TVPSAIRALLEADAVPRSVRCINL---AGELLQQELVDELYARLGAVEVYDL---YGPSE 740
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
TY + + + IGRP+ N +Y+LDE P GE+ + GA LA
Sbjct: 741 ---STTYSTVCLRTR---GGSASIGRPIANTQVYVLDESGDPLPSGAIGEIHIGGAGLAR 794
Query: 320 GYVG--GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHRVD 376
GY+ A +F N HA R+YRTGD G + Y GR D Q KIRGHRV+
Sbjct: 795 GYLDRPEATAEKFVFNRHAG----ARVYRTGDLARWTADGRLQYRGRKDNQEKIRGHRVE 850
Query: 377 LLEVERALAQVPGVDKCVVLCYGL--DRGNPEILGFVTTKPGA-----RTSAQHIE--GK 427
E+E L + P V +C+V+ G D G ++ +V A +A I G+
Sbjct: 851 PGEIEACLREHPSVAECIVVGRGSAGDAGGRYLVAYVVAAGDAGPVQDEAAAGLIAELGR 910
Query: 428 -LRSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
L + L Y +P + + + ++PL NGKVDR L
Sbjct: 911 FLAARLPAYALPSRFVALSALPLTPNGKVDRNAL 944
>UniRef50_Q1D6A1 Cluster: Non-ribosomal peptide synthase/polyketide
synthase; n=2; Cystobacterineae|Rep: Non-ribosomal
peptide synthase/polyketide synthase - Myxococcus xanthus
(strain DK 1622)
Length = 4375
Score = 185 bits (450), Expect = 5e-45
Identities = 164/554 (29%), Positives = 254/554 (45%), Gaps = 45/554 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL KAG A+VP++P++P R+TH+++DA S+V+ D A + G + +
Sbjct: 2810 VVGLLGVLKAGGAFVPLDPAYPTARLTHMMRDAGLSVVVTMD-AIADVLPAGGELLVALD 2868
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
++ + ++ P + +A V+YTSGSTG PKGV + + +CN L R
Sbjct: 2869 GDRRQLARNPSEPPRVGSL-----PEHLAYVIYTSGSTGTPKGVLVPHQGLCNTLGTIIR 2923
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI--ERLVL 197
+ + AL F SV E+ L+ G L + RE+ L + R +
Sbjct: 2924 AHDVRPGRRV-LQAAALGFDASVLEVLSTLVAGAELHLAPRESLLPGAPLRGLLESRGIT 2982
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
TL S L L P PL L+ + +GE S ELA + + G +L N YG
Sbjct: 2983 TVTLTPSSLSQLE--PEGLPL--LETVISAGEACSPELARRW------KPGRRLLNGYGP 3032
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
TE T S +LD+ IGRP+ N Y+LD P PGE+++ G +
Sbjct: 3033 TEASVCATL-----STELDVERP-DIGRPVANMRAYVLDGRGQPVPPGVPGELYLGGPGV 3086
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHR 374
A GY+G A RF + + + RLYRTGD L G + Y GRTD QVK+RG R
Sbjct: 3087 ARGYLGRPELTAERFVPDAFSGEAG-ARLYRTGDRVRFLADGRLEYLGRTDFQVKLRGFR 3145
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L EVE L Q P V V L +G ++G+V A A + ++ L
Sbjct: 3146 IELGEVEAVLRQYPDVRDAVALVREDTQGARRLVGYVV--QAAELDASALRSFMKERLPD 3203
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXX 493
+++P + ++++PL +GKVDR L + +A+V +
Sbjct: 3204 HLVPAAFVALDALPLSPSGKVDRAAL--PAPDAARGGNAKVFTEPRTEAEKALAALWT-- 3259
Query: 494 XXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFLGASTLGE 553
VLG +SL F+ELGG+S+ I +++ + G +E + TL E
Sbjct: 3260 ------QVLGVE---RVSLHDNFFELGGDSILGIQIVSRAKALGLELEPAMLFERQTLVE 3310
Query: 554 VLSKMSTDPNGGAD 567
+ + T G A+
Sbjct: 3311 LAAAAGTAKAGTAE 3324
>UniRef50_Q1D4E9 Cluster: Non-ribosomal peptide synthase/polyketide
synthase; n=2; Cystobacterineae|Rep: Non-ribosomal
peptide synthase/polyketide synthase - Myxococcus xanthus
(strain DK 1622)
Length = 2973
Score = 185 bits (450), Expect = 5e-45
Identities = 156/564 (27%), Positives = 266/564 (47%), Gaps = 41/564 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A L +GAAY+P++ P R ++++ L + P +ES
Sbjct: 601 VVAALGVLSSGAAYLPIDAGLPHERRVFMMRNGGAELAV----TQPKFAQESWPEGVQVL 656
Query: 80 ELAQEATSHSADEPMDAETLAPLTS-DSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ +A S ++ P LAP+ + +A +LYTSGSTG P G L+++ + N + W
Sbjct: 657 VVTPDAFSEYSEAP-----LAPVQKPEDLAHILYTSGSTGQPNGAMLTHAGMVNGVEWTN 711
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQ---KLVNIERL 195
R F + + + +AL SV +++G L G AL++ + RDP +L++ +
Sbjct: 712 RKFGVGPEDRV-IALSALHHDFSVYDVFGTLSAGAALVMPDASSRRDPSHWAELMSRHGV 770
Query: 196 VL---VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
+ VP ++ +L YL G +R L+L + G+ L + + FG+ KL
Sbjct: 771 SIWSTVPAMMEMLLTYLE-GSNARLTCPLRLVMLGGDWLPVTMPARLRAKFGD---VKLM 826
Query: 253 NFYGSTEV-MGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
+ G TE + ++++ V+E ++ +IP G+P+ N Y+LDE L PGE+
Sbjct: 827 SVGGPTETSLWNISHPVVEADERRR---SIPYGKPISNTKYYVLDEHLDERPIWVPGELC 883
Query: 312 VAGANLAAGYVG-GGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVK 369
AG +A GYVG G G+ +F +P +RLYRTGD G L G + + GR D Q+
Sbjct: 884 CAGVGVALGYVGAGAGSKKFTVHPRTG----ERLYRTGDLGRYLPDGTIEFLGRVDFQLS 939
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR-TSAQHIEGKL 428
IRG R++ E+E AL Q P + VV G D ++ +V R +H+ L
Sbjct: 940 IRGQRIEPGEIEAALLQEPSISAAVVGAVG-DHHEKRLVAYVVASDTKRGVDTRHVREFL 998
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXX 487
L +++P + +E++PL N KVDR+ L ++ E + +
Sbjct: 999 SRKLPEHLVPATYVVLEALPLTRNAKVDRKA-LPHPDHVARPTQREESKPAAAARPGREA 1057
Query: 488 XXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFL 546
V VLG + F+ELG NS++ I +L+++ G V ++D
Sbjct: 1058 QALQQSIAKAVAEVLGVP---EVHPDRNFFELGANSVHLIKLHLELKEKLGLSVPVTDLF 1114
Query: 547 GASTLGEVLSKMSTDPNGGADSKE 570
G T+ + ++++ GG + E
Sbjct: 1115 GRPTVKVLAARLAA--AGGEEKPE 1136
>UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria|Rep:
Beta-lactamase, putative - Stigmatella aurantiaca DW4/3-1
Length = 3136
Score = 185 bits (450), Expect = 5e-45
Identities = 136/446 (30%), Positives = 213/446 (47%), Gaps = 28/446 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAGAAYVP++P++P R+ + +DA SL++ D+ + +G +
Sbjct: 1267 VIGLLAILKAGAAYVPLDPAYPAERLIYSFQDAGASLLVTQDTLR-HLLPIAGAKTVCLD 1325
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + S D P + + ++A VLYTSGSTG PKGV + + + W
Sbjct: 1326 SGWEPISRESTDNPRSS-----VLPSNLAYVLYTSGSTGRPKGVAIEHHNAAVFIQWSLN 1380
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
F + T++ F S+ E++ PL G +L+ S L + + L+
Sbjct: 1381 CFSAQQLAGVLA-STSICFDLSIFELFAPLCSGGTVLLASNALALP--SLPAAQEVTLIN 1437
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
T+ +I + L L +GE LS L + + + N YG TE
Sbjct: 1438 TVPSAIAELARTNAIPSSIHTLNL---AGEPLSGSLVRALYSLPSIQHVF---NLYGPTE 1491
Query: 260 VMGDVTY--YVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
D TY + L D PTI GRP+ Y+LD +L PGE++++G+ L
Sbjct: 1492 ---DTTYSTFTLIPKDASS-EPTI--GRPISGTRAYVLDRQLHLVPRGVPGELYLSGSGL 1545
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGHR 374
A GY+ A RF NP +T+P RLY+TGD V G + Y GR D QVKIRG R
Sbjct: 1546 ARGYINRPELTAERFLPNPFSTEPG-SRLYKTGDLARFAVDGNLEYLGRIDHQVKIRGFR 1604
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E+E L PG+ + VL + G+ ++ +V + + L+ L
Sbjct: 1605 IELGEIESILLTQPGLHQAAVLAHEEAPGDKRLVAYVVAARNHSFTPAELRRLLKERLPD 1664
Query: 435 YMMPQV-IEVESIPLLVNGKVDRQGL 459
YM+P + ++++PL NGK+DR+ L
Sbjct: 1665 YMVPSAFVLLDALPLTPNGKLDRKAL 1690
Score = 40.7 bits (91), Expect = 0.15
Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 9/140 (6%)
Query: 44 RITHILKDAEPSLVIYDD---SADPSMFKESGVPFASFEELAQEATSHSADEPMDAETLA 100
R+ +++DA+ +V+ S S+F++ F+ L AT D
Sbjct: 145 RLRAMIQDAQAKVVLTTSFILSMGESLFEQE----PDFKNLHWIATDDLPKGAPDRWVQP 200
Query: 101 PLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSEEICV-WKTALTFV 159
++ +++A + YTSGSTG PKGV L++ + L TF S+ +CV W +
Sbjct: 201 SVSGNTLAFLQYTSGSTGAPKGVMLTHDNLLCNLEMIAHTFQIR-SDSVCVIWLPPYHDM 259
Query: 160 DSVCEIWGPLLHGRALLILS 179
+ I P+ G ++S
Sbjct: 260 GLIGGILEPVYTGMRTTLMS 279
Score = 37.9 bits (84), Expect = 1.0
Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 272 SDQLDLYPTIPIGRPLDNCAIYLLDEELS-PTRDSEPGEVWVAGANLAAGY-VGGGGANR 329
S +LD + G+ + N I ++D S P + GE+WV G ++A GY +
Sbjct: 403 SGELDSRTLVGCGQTVPNQEILIVDPVSSVPCPPGKVGEIWVCGPSVAQGYWQKPTETGQ 462
Query: 330 FCDNPHATQPEFQRLY-RTGDFGTLVKGAVLYAGRTDAQVKIRG 372
A+ E R+Y RTGD G L + + GR + IRG
Sbjct: 463 IFQARPASGGE--RVYLRTGDLGFLKERELFVTGRQKDLIIIRG 504
>UniRef50_Q8CUZ9 Cluster: Monomodular nonribosomal peptide
synthetase; n=1; Oceanobacillus iheyensis|Rep:
Monomodular nonribosomal peptide synthetase -
Oceanobacillus iheyensis
Length = 2373
Score = 184 bits (449), Expect = 6e-45
Identities = 136/449 (30%), Positives = 225/449 (50%), Gaps = 32/449 (7%)
Query: 21 MALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVP--FASF 78
+++LA WKAGAAY+P++P++P+ R+ ++L++A+P ++I D A +S VP F
Sbjct: 522 ISILAIWKAGAAYLPLDPTYPEERLEYMLENADP-IMILTDGASCRSIPDSFVPIMFNLD 580
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
E L E ++ + P A + A ++YTSGSTG PKGV + + + L +
Sbjct: 581 EGLFNEEVNNQS--PSSINLFAEQSLKHAAYMIYTSGSTGKPKGVVVPAEGLVHFLQYMN 638
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP---QKLVNIERL 195
F S + + T ++F SV E++ PL+ G +++ RE +DP + +N +++
Sbjct: 639 NVFSLSVKDRLLA-LTTISFDISVLELFLPLVSGATCVLMKREIVQDPILLNQTINNQKI 697
Query: 196 VLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFY 255
+ M LA AS L +K V GE L LA E K + N Y
Sbjct: 698 TAIQATPTHWQMILAHQQAS--LTDVKALV-GGEALPSYLAEEMVK-----TCQSVTNLY 749
Query: 256 GSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGA 315
G TE T Y L+ + L IG P+D A+Y+LD++L GE+++AGA
Sbjct: 750 GPTETTIWSTVYELDKEEPKGL-----IGAPIDETAVYVLDQDLQLVPPEVDGELYIAGA 804
Query: 316 NLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLV-KGAVLYAGRTDAQVKIRG 372
+ GY G A R+ NP R+YRTGD G++ Y R D QVK+RG
Sbjct: 805 GVTRGYYGRPSLTAERYVANPFGDSG--SRMYRTGDIVQWTSNGSLEYIKRADDQVKLRG 862
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGA-RTSAQHIEGKLRSA 431
HR++L E+E+ ++ V+ GN +++ ++ GA + + + +
Sbjct: 863 HRIELGEIEKVISSFSPNMSAKVIVREDTPGNQQLVAYLV---GADEITKEELITHAKHT 919
Query: 432 LTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ YM+P ++ ++ PL +NGK+D++ L
Sbjct: 920 VPEYMIPDSIVYLDEFPLTLNGKLDKKKL 948
Score = 183 bits (445), Expect = 2e-44
Identities = 130/452 (28%), Positives = 228/452 (50%), Gaps = 22/452 (4%)
Query: 18 STIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFAS 77
S ++++LA K G+AYVP++P +P RI++IL DA PS+VI ++ ++ + + +
Sbjct: 1567 SMMVSILAVLKTGSAYVPVDPDYPDERISYILSDANPSIVITNEKSNQTTEDFTSLHVID 1626
Query: 78 FEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
+++ +++ ++ +++ + A ++YTSGSTG PKGV + + + RL +
Sbjct: 1627 IADVSSRILQAYSNQNINQS----ISAMNAAYIIYTSGSTGKPKGVVIPHHNVI-RLLNE 1681
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ER 194
+ + +S+++ + F SV EIWG LL+G L+I+ +R P + +++ E+
Sbjct: 1682 TDEWYHFNSDDVWTMFHSYAFDFSVWEIWGALLYGGKLVIVPYNVSRMPIEFLDLLVQEQ 1741
Query: 195 LVLVPTLLRSILMYLALGPASRPLRR---LKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ ++ + + R L R L+ V GE L ++F N KL
Sbjct: 1742 VTVLNQTPSAFYQLMYAEQERRDLSRKLSLRYVVFGGEQLELARLKDWFTLHENST-TKL 1800
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE V+Y L + +D IG + + IY+LD+ L P GE++
Sbjct: 1801 INMYGITETTVHVSYLEL-NEEIIDQQGNSLIGTNIPDLEIYILDDFLQPVPIGVTGEMY 1859
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQV 368
VAG LA GY+ A+RF NP R+Y+TGD L G + Y GR+D QV
Sbjct: 1860 VAGGGLARGYLNQSSLTASRFVANPFGEAG--SRMYKTGDLAKWLDDGTIDYIGRSDHQV 1917
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG+R++L EV + + + G+ +++ ++ T R + ++ +
Sbjct: 1918 KIRGYRIELGEVNAHIISHESIKEAATTVLN-QHGDNQLVSYIVTDKEVRDA--DLKAYI 1974
Query: 429 RSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
S L YM+P + ++ IPL +GK+D + L
Sbjct: 1975 ASFLPGYMIPSTFVHIDRIPLTAHGKLDTKNL 2006
>UniRef50_Q311J1 Cluster: Amino acid adenylation; n=9; Bacteria|Rep:
Amino acid adenylation - Desulfovibrio desulfuricans
(strain G20)
Length = 3194
Score = 184 bits (449), Expect = 6e-45
Identities = 166/585 (28%), Positives = 269/585 (45%), Gaps = 46/585 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I A+L +AG AYVP++ +P GRI H++ + + +V+ D + + K +G E
Sbjct: 2368 IAAVLGILQAGGAYVPLDVEYPDGRIRHLISELKTGVVVTDAANSARIEKSAGRTILIME 2427
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L AD+P + + + T D +A ++YTSGSTG PKGV S+ N + R
Sbjct: 2428 HL-----EPVADQPEVSASRS--TPDDLAYIIYTSGSTGTPKGVMTSHKGAVNTVRDINR 2480
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI---ERLV 196
+ + + L F SV +I+G L G +L++ ++P +++ ER+
Sbjct: 2481 RLAVTAKDNV-AGLANLNFDLSVYDIFGVLGCGGSLVLPDIRHMKNPASWIDMIEQERIT 2539
Query: 197 L---VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L VPTL++ +L YL G R L+ L+ + SG+ + +LA E + L
Sbjct: 2540 LWNSVPTLMQMLLEYLPNGLEGR-LQTLRCIMLSGDWIPIQLAKEIKSRLPLAALFSLG- 2597
Query: 254 FYGSTEVMGDVTYYVLEGSDQL-DLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
G+TE + V+ +Q+ + ++P GR +DN + +LD L D+ G +++
Sbjct: 2598 --GATEAS---IWSVIHAVEQIPPHWNSVPYGRAMDNQTVQVLDHLLRERPDNVTGGIYL 2652
Query: 313 AGANLAAGYVGGGGANRFCDNPHATQP-EFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY A + T P + +RLYRTGD G L G++ GR D Q+KI
Sbjct: 2653 GGTGLAEGY---WNAPEKTERSFITHPADGRRLYRTGDLGRYLPDGSIEILGREDFQLKI 2709
Query: 371 RGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRS 430
G+R++ E+E L P V + +V + G + T K TS + + +
Sbjct: 2710 SGYRIEPGEIEAQLNSHPAVSQSIVSAITDNSGKKVLCAHWTGKKD--TSPEELALFISE 2767
Query: 431 ALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L HYM+P++ + V + PL NGKVDR L E+ AV
Sbjct: 2768 TLPHYMVPKIFVHVTAFPLNANGKVDRSALHVPQEH--------YAV----PERTATFSA 2815
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDR-GYYVEISDFLGA 548
+ VL G + F+++GG+SL +I I L+ + G V + +F
Sbjct: 2816 AEQLVAQAMTEVLAVQPAGP---EADFFDMGGDSLLAIRLINSLKKKTGISVSVPEFFQD 2872
Query: 549 STLGEVLSKMSTDPNGGADSKEATFTAVPMRDEHKKEVIDMVESS 593
ST+ V K++ N G S+ T P ++ V + E S
Sbjct: 2873 STIKAVAEKIAAHGNTGTGSRAETCLTAPAGQQNGPSVYLVHEGS 2917
>UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular
organisms|Rep: Peptide synthetase - Mycobacterium
smegmatis
Length = 5990
Score = 184 bits (449), Expect = 6e-45
Identities = 140/444 (31%), Positives = 217/444 (48%), Gaps = 33/444 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+++L+ K GAAY+P++P+ P RI ++ DA+P + +AD +
Sbjct: 3536 ILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAAL--TTADLRSRLDQ-------Y 3586
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+LA + A + ++ L+ D +A + YTSG+TG+PK V +++ + +
Sbjct: 3587 DLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHA 3646
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P + W + L F SV EIWG LLHG L+++ P L N+ V
Sbjct: 3647 DLPSGPGQVWSQWHS-LVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVS 3705
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L ++ L P L + +GE EL + G + N YG TE
Sbjct: 3706 VLCQTPSAAGMLSPEGLESTTL---IVAGEACPTELVDRW------APGRVMINAYGPTE 3756
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
T Y PIG P+ A+++LD+ L P + GE++VAG +A
Sbjct: 3757 A----TIYAAMSEPLTAGTGVAPIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVAT 3812
Query: 320 GYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHRVD 376
GY+G A+RF P E R+YRTGD G + Y GR D QVKIRG+R++
Sbjct: 3813 GYIGRPDLTASRFVACPFGETGE--RMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIE 3870
Query: 377 LLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYM 436
L E++ ALA++ GVD+ VV+ G+ ++G++T G AQ + L +L YM
Sbjct: 3871 LGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT---GTADPAQ-LRTALAESLPAYM 3926
Query: 437 MP-QVIEVESIPLLVNGKVDRQGL 459
+P V+ +++IPL VNGK+DR+ L
Sbjct: 3927 VPTAVVVLDTIPLTVNGKLDRRAL 3950
Score = 183 bits (445), Expect = 2e-44
Identities = 168/574 (29%), Positives = 260/574 (45%), Gaps = 56/574 (9%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADP-SMFKESGVPFASF 78
++ +LA K GAAY+P++P+ P RI +LKDA P + SAD + SGVP
Sbjct: 2020 VVTILAILKTGAAYLPIDPAHPDARIEFVLKDAAPVAAV--SSADLCTRLIASGVPVIEV 2077
Query: 79 EELAQEATSHSADEPMDAETLAPLTS-DSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQ 137
++ A A +A T P+ + D IA ++YTSG+TG PKGV +++ + L
Sbjct: 2078 DDPAIGA---------EASTSLPVPAVDDIAYIIYTSGTTGTPKGVAVTHRNVAQLLDTL 2128
Query: 138 FRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VN 191
+ C +L F SV EIWGPLL+G LL++ R P+ L
Sbjct: 2129 GAQLELGQTWTQC---HSLAFDYSVWEIWGPLLNGGRLLMVPDAVVRSPEDLHAMLVAEQ 2185
Query: 192 IERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKL 251
+ L P+ ++ AL P +L+ V GE L S + + ++
Sbjct: 2186 VSMLSQTPSAFYALQTADALYPERGEQLKLQTVVFGGEALEPHRLSGWMH--AHPGMPRM 2243
Query: 252 ANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVW 311
N YG TE ++ + +D + T PIG PL++ + ++LD L GE++
Sbjct: 2244 INMYGITETTVHASFREIGEADLAN--STSPIGVPLEHLSFFVLDGWLRQVPVGVVGELY 2301
Query: 312 VAGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQV 368
VAG LA GY+ + RF P R+YRTGD G + Y GR D QV
Sbjct: 2302 VAGEGLACGYISRSDLTSTRFVACPFGAPGA--RMYRTGDLVRWGADGQLQYVGRADEQV 2359
Query: 369 KIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKL 428
KIRG+R++L EV AL + GV++ V+ G+ ++G+VT GA L
Sbjct: 2360 KIRGYRIELGEVHAALVGLDGVEQAAVIAREDRPGDKRLVGYVT---GA-VDPVKARAAL 2415
Query: 429 RSALTHYMMPQVIEV-ESIPLLVNGKVDRQGL-LKMYENTNNNDDAEVAVDIDCSXXXXX 486
+ YM+P I V ES+PL VNGK++ + L Y++ + AV+
Sbjct: 2416 AERIPAYMVPAAIVVMESLPLTVNGKLNTRALPAPEYQDADQYRAPANAVE--------- 2466
Query: 487 XXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYYVEISDFL 546
VLG G + F++LGG+S++S+ + + R G D
Sbjct: 2467 -----ELLTGIYAQVLGVERVG---VDDSFFDLGGDSISSMQVVARARAAGLVCRPRDIF 2518
Query: 547 GASTLGEV--LSKMSTDPNGGADSKEATFTAVPM 578
T+ + + ++ +G AD+ A P+
Sbjct: 2519 VEQTVSRLAQVVTLADGESGVADTGVGPVVATPI 2552
Score = 179 bits (436), Expect = 2e-43
Identities = 145/446 (32%), Positives = 213/446 (47%), Gaps = 37/446 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+A+LA K GAAY+P++PS P R+ +L DA+P + F F+
Sbjct: 5030 IVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSR--------FDGFD 5081
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E A E + TL + D IA ++YTSG+TG+PKGV +++ + L
Sbjct: 5082 LQVVEVDD-PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPA 5140
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
P W + L F SV EIWG LLHG L+I+ P L + V
Sbjct: 5141 ELPAGPGAVWSQWHS-LVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVN 5199
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
L ++ + P L V +GE E+ + + N YG TE
Sbjct: 5200 VLYQTPSAVRMMSPEGLEGTAL---VVAGEACPTEVVDRWAV------DRVMINAYGPTE 5250
Query: 260 --VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
+ ++ + GSD +PIG P+ A ++LDE L P GE+++AG +
Sbjct: 5251 STIYAAISAPLSPGSD------VVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAGRGV 5304
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHR 374
GYVG G RF P +P R+YRTGD G + Y GR D QVKIRG+R
Sbjct: 5305 GVGYVGRSGLTGTRFVACPFG-EPG-ARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYR 5362
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTH 434
++L E++ AL+ V GVD+ VV+ G+ ++G++T G A +L + L
Sbjct: 5363 IELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT---GTADPAA-ARSELTNRLPA 5418
Query: 435 YMMP-QVIEVESIPLLVNGKVDRQGL 459
YM+P V+ +E++PL VNGK+DR+ L
Sbjct: 5419 YMVPAAVVTLETLPLTVNGKLDRRAL 5444
Score = 155 bits (376), Expect = 4e-36
Identities = 138/456 (30%), Positives = 205/456 (44%), Gaps = 36/456 (7%)
Query: 19 TIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASF 78
+++A+L +KAGAAYVP++P+ P R+ IL DA P V+ S F
Sbjct: 522 SVIAILGAFKAGAAYVPVDPAVPAARVRFILDDASPVAVVTTAELR-SRFDG-------- 572
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+LA A + A ++ D IA V+YTSG+TG PKGV +++ + + +
Sbjct: 573 HDLAVIDIDDPAIASLPATAVSDPRPDDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVLE 632
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLV 198
P +C +L F SV EI LL G L+++ P+ ++ V
Sbjct: 633 ERLPKPGVWPLC---HSLAFDASVWEISNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQV 689
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L ++ L P L + L V GE L + + N YG T
Sbjct: 690 TFLTQTPSAVAMLSPDG--LESMTLAVV-GEACPPALVDRW------ATNRTMINAYGPT 740
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E T V S +PIG L A+++LD L P GE++VAG +
Sbjct: 741 ET----TICVTSSSPLEPGSVVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVT 796
Query: 319 AGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQVKIRGHRV 375
GY+G G A+RF P +P R+YRTGD + G + Y GR D QVKIRG+R+
Sbjct: 797 CGYIGRSGLTASRFVPCPFG-EPG-ARMYRTGDLVRWGRDGQLEYLGRADEQVKIRGYRI 854
Query: 376 DLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHY 435
+L EV+ ALA + GV+ + G+ ++G++T I +L L Y
Sbjct: 855 ELGEVQSALAALDGVESAAAIMREDRPGDRRLVGYIT----GTADPVDIRAELADRLPPY 910
Query: 436 MMPQVIEV-ESIPLLVNGKVDRQGL-LKMYENTNNN 469
M+P I V ++PL + K+D + L Y N N
Sbjct: 911 MVPTAIVVLPALPLTSSNKLDTRALPAPEYANAEKN 946
>UniRef50_Q0LLT6 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2844
Score = 184 bits (449), Expect = 6e-45
Identities = 135/447 (30%), Positives = 216/447 (48%), Gaps = 21/447 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LL AG AYVP++PS+P R+ +L+DA + ++ SG+P S
Sbjct: 2047 MVGLLGIVIAGGAYVPLDPSYPAERLAFMLEDARVAALVTQKRL------LSGLPADSIP 2100
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
L + D + +T +A ++YTSGSTG PKG + +S + N L W
Sbjct: 2101 RLCLDTDWSLVAGNQDCPPASAVTPAHLAYMIYTSGSTGRPKGTMIQHSGLANYLTWAVD 2160
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDP--QKLVNIERLVL 197
+ + + V+ ++++F ++ ++GPLL GR + +L + D L E L
Sbjct: 2161 AYAMAAGDGAPVY-SSVSFDLTITGLFGPLLAGRTVHLLPEDAGADGLGANLSVAETYSL 2219
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V + + PA + R + +V GE L ++ + F++ + L N YG
Sbjct: 2220 VKITPAHLEILNHQMPAHQAAGRTRAFVIGGENLRADMVA-FWRDHAPQTA--LINEYGP 2276
Query: 258 TE-VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE V+G Y V + + + +PIGRP+ N +Y+LD L GE+++ GA
Sbjct: 2277 TETVVGCCVYTVTTDTPAVGV---LPIGRPIANTQMYVLDPRLQLVPIGVVGELYIGGAG 2333
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
+ GY A RF +P QP RLY+TGD G L G + GR D QVK+RG
Sbjct: 2334 VGRGYHRRPDLTAERFVPDPFGGQPG-ARLYKTGDLGRILADGTLECLGRVDHQVKVRGF 2392
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L E+E AL + GV + VV + G+ ++ +V P ++ L+ L
Sbjct: 2393 RIELEEIEAALLRQAGVREAVVAARRQESGDIQLAAYVVAAPDNPLQIPTLKQSLQELLP 2452
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGL 459
YM P ++ ++ +PL NGKVDR L
Sbjct: 2453 AYMAPSHIMLIDELPLTSNGKVDRGAL 2479
Score = 157 bits (381), Expect = 1e-36
Identities = 131/467 (28%), Positives = 216/467 (46%), Gaps = 45/467 (9%)
Query: 107 IAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSDSEEICVWKTALTFVDSVCEIW 166
+A ++YTSGSTG PKGV ++++ + W F +D E T++ F S+ E +
Sbjct: 5 LAYIIYTSGSTGRPKGVMITHANAAFFMDWALEVFSPADLEGPLA-ATSMCFDISIFEFF 63
Query: 167 GPLLHGRALLI------LSRETTRDPQKLVNIERLVLVPTLLRSILMYLALGPASRPLRR 220
PL G ++L+ L+ P LVN VP++ +L L P+ R +
Sbjct: 64 APLSCGGSVLLAENILHLAAMPATPPITLVNT-----VPSVFAEVLRDTELPPSVRVVN- 117
Query: 221 LKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTEVMGDVTYYVLEGSDQLDLYPT 280
+GE L + L + + G ++ NFYG +E D TY ++ + P
Sbjct: 118 -----LAGEALPRVLVDQLY---GLPTVERVYNFYGPSE---DTTYSTIDCVARDGAGPP 166
Query: 281 IPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAAGYVGGGG--ANRFCDNPHATQ 338
P+GR +DN Y+LD P GE+++ GA ++ GY G A R+ +P +
Sbjct: 167 -PLGRTIDNSEGYVLDGFQQPVPVGIAGELYLGGAGVSRGYFGRPALTAERYLPDPFSGV 225
Query: 339 PEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLC 397
R+YRTGD G + Y GR D QVK+RG R++L EVE AL++ V + V+
Sbjct: 226 LG-ARMYRTGDRVRRQADGTLEYLGRMDRQVKLRGFRIELGEVEAALSEQAAVQEAAVVI 284
Query: 398 YGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALTHYMMP-QVIEVESIPLLVNGKVDR 456
RG+P ++G+V + G + ++ LR L YM+P QV+ + +P +GK+DR
Sbjct: 285 KASPRGDPTLVGYVVARAGEALDSTTVQAALRERLPEYMVPSQVVVLLGLPRTSSGKLDR 344
Query: 457 QGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXXXXXXTVGAVLGRAARGTLSLRSGF 516
+ L + D + + A + R R +L S F
Sbjct: 345 RALPE--------------PDFGRAVAAVAALTADGEALAAIWAEVLRVPRASLDAHSNF 390
Query: 517 YELGGNSLNSIYTITKLR-DRGYYVEISDFLGASTLGEVLSKMSTDP 562
+ LGG+SL + + ++R + + + + TLGE+ + + P
Sbjct: 391 FALGGHSLLATRIVARVRQELQIDLPLRRLFESPTLGELAAVLRVQP 437
Score = 155 bits (376), Expect = 4e-36
Identities = 146/551 (26%), Positives = 251/551 (45%), Gaps = 37/551 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ALLA K+G A+ + P ++ ++++ P++V+ D +A P + +G
Sbjct: 982 LVALLAVLKSGGAFALVNPR-NLDQLPALIEELAPAVVLRDATA-PQVPATAGRAVLDLS 1039
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E S A +D L P DS A ++ T G+ G + V LS+ A+ RL
Sbjct: 1040 ADWAEIASLPAVS-LD-HMLHP---DSAACLVQTDGAAGTRRLVVLSHRALGQRLLAAQA 1094
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLI-LSRETTRDPQKLVNIERL-VL 197
+P ++ + + AL D+V PL G A+++ ++ + P + + V
Sbjct: 1095 AYPLYPTDRV-LHSAALETGDAVWAWLAPLTAGSAVVLDVAGGESAGPSLIETVTAQDVT 1153
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V LL S L L P L++ + +GE LS+ FF+ E L N YG+
Sbjct: 1154 VARLLPSQLDVLLDAPRFTECTTLRMVLAAGEPLSQTTQDRFFERSAAE----LYNLYGA 1209
Query: 258 TEVMGD-VTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
E D + + +D D P+ P+G PL+ + LLD++ GE+++ GA
Sbjct: 1210 AETTLDALAWRCARDADLSD--PSAPLGAPLEATQVALLDDQGRVVPVGIAGELYLGGAG 1267
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDAQVKIRGH 373
++ GY G A R+ +P + R+YRTGD G + Y GR + QVK+RG
Sbjct: 1268 VSRGYFGRPALTAERYLPDPFSGVLG-ARMYRTGDRALYRADGMLEYRGRVEQQVKLRGF 1326
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++L EVE AL++ V + V+ RG+P ++G+V + G + ++ LR L
Sbjct: 1327 RIELGEVEAALSEQAAVQEAAVVIKASPRGDPTLVGYVVARAGEALDSTTVQAALRERLP 1386
Query: 434 HYMMP-QVIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
YM+P QV+ + +P +GK+DR+ L + D +
Sbjct: 1387 EYMVPSQVVVLLGLPRTSSGKLDRRALPE--------------PDFGRAVAAVAALTADG 1432
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLR-DRGYYVEISDFLGASTL 551
+ A + R R +L S F+ LGG+SL + + ++R + + + + TL
Sbjct: 1433 EALAAIWAEVLRVPRASLDAHSNFFALGGHSLLATRIVARVRQELQIDLPLRRLFESPTL 1492
Query: 552 GEVLSKMSTDP 562
GE+ + + P
Sbjct: 1493 GELAAALRVQP 1503
>UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-CYA
116|Rep: OciB - Planktothrix agardhii NIVA-CYA 116
Length = 4728
Score = 184 bits (449), Expect = 6e-45
Identities = 131/457 (28%), Positives = 228/457 (49%), Gaps = 30/457 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LLA K G AYVP++P +PQ RI+ +L+D + +++ +S S+ + +
Sbjct: 2684 IVGLLAILKVGGAYVPIDPDYPQERISFMLQDTQVKIILTCESLQNSLQNHQTIVICLDK 2743
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ Q + ++ E ++ + +++D++A V+YTSGSTGIPKGV +++ A+ NRL
Sbjct: 2744 DWQQ--INQASLENLN----STVSADNLAYVIYTSGSTGIPKGVIVTHQAV-NRLVLNTN 2796
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL-VNIERLVLV 198
++ + + V + + F + EIWG LL+G ++I+++ PQ+L ++++ +
Sbjct: 2797 YIQFTPDDRV-VQASNIAFDAATFEIWGALLNGAKIIIIAKSVLLSPQELALSLKENQIS 2855
Query: 199 PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGST 258
L + + L+ + GE + + E + + +L + YG T
Sbjct: 2856 VLFLTTAFFNQLANLVPQAFSSLRCLLFGGEAVEPKWVQEVLEKGAPQ---RLLHVYGPT 2912
Query: 259 EVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLA 318
E ++Y++E + TIPIG+ + N IYLLD+ L P GE+ + G LA
Sbjct: 2913 ENTTFSSWYLVE--NVASTATTIPIGKAIANTQIYLLDKNLQPVPIGVVGELHIGGMGLA 2970
Query: 319 AGYVGGG--GANRFCDNPHATQP------------EFQRLYRTGDFGT-LVKGAVLYAGR 363
GY+ +F NP E +LY+TGD L G + Y GR
Sbjct: 2971 KGYLNRPELTQEKFIPNPFEKDEVIPPTPLNKDGNEPSKLYKTGDLARYLPDGNIEYLGR 3030
Query: 364 TDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQH 423
D QVKIRG R++L E+E L Q V V+ + G+ ++ ++ +P +
Sbjct: 3031 IDNQVKIRGFRIELGEIEALLNQNEDVQSACVIAREDNPGDKRLVAYLVPQPEIILTIDE 3090
Query: 424 IEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
I L++ L YM+P + +E++PL NGK+DR+ L
Sbjct: 3091 IRQFLKAKLPDYMVPNAFVILEALPLTPNGKIDRRAL 3127
Score = 178 bits (433), Expect = 5e-43
Identities = 140/453 (30%), Positives = 223/453 (49%), Gaps = 26/453 (5%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LLA KAG AYVP++P +PQ R++++ +DA+ SL++ S S+ E V +
Sbjct: 1614 IVGLLAVLKAGGAYVPLDPDYPQQRLSYMAEDAKISLLLTQQSLLSSLPVED-VGVIVLD 1672
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ A+ T S + P ++ + +++ VLYTSGSTG PKGV L++ A+ N W
Sbjct: 1673 KSAESLTVQSLENP-----VSEVVPENLLCVLYTSGSTGKPKGVMLTHEALVNHSWGISE 1727
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRE---TTRDPQKLVNIERLV 196
F ++S+ + + + F + EI+ L G +++ + T D + E L
Sbjct: 1728 IFGLTESDRVLQF-ASFGFDVAAEEIFPTWLKGGTVVLRPWQMFPTLTDFADFIEQESLT 1786
Query: 197 LV---PTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L+ P + ++ A+ P L++ G+ + E + + ++ G + + N
Sbjct: 1787 LLNITPAYWHEWAIAVSQSSATVP-SSLRVVAVGGDAVLPETVNIWREWVGKQ--VQCIN 1843
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE + L S Q + ++ IGRP+ N Y+LD+ L P GE+ +
Sbjct: 1844 VYGPTEASVTAIVHDLLDS-QSEKINSVLIGRPIANTKAYILDQNLQPAPIGVKGELHLC 1902
Query: 314 GANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKI 370
G LA GY+ A +F DNP A P F RLY+TGD L G++ GR D QVKI
Sbjct: 1903 GVRLARGYLNRPELTAEKFIDNPFAAAP-FNRLYKTGDLARYLPNGSIECFGRIDNQVKI 1961
Query: 371 RGHRVDLLEVERALAQVPGVD-KCVVLCYGLDRGNPEILGFVTTKPGAR--TSAQHIEGK 427
RG R++L E+E L Q V CV++ L G ++ ++ +
Sbjct: 1962 RGFRIELGEIEAILNQHLDVQTSCVIIREDLP-GQKYLVAYIVISSHYERIPMISELRQF 2020
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L L YM+PQ + +ES+PL N KVDR+ L
Sbjct: 2021 LAGNLPMYMVPQAFVFLESLPLTTNRKVDRRAL 2053
Score = 153 bits (370), Expect = 2e-35
Identities = 126/469 (26%), Positives = 217/469 (46%), Gaps = 40/469 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ +L KAG AY+P++ ++P+ RIT++L+D + ++++ + + G +
Sbjct: 528 IVGILGILKAGGAYLPLDINYPKERITYLLEDTQLNILLTQSQFLGQLPQFQGTTICLDQ 587
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + A + + ++ + ++A ++YTSGSTG PKGV + + +I N + R
Sbjct: 588 DWSIIANQSTVNPIVEVD------QHNLAYIIYTSGSTGKPKGVMIEHRSIVNYILTAIR 641
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNI----ERL 195
++ ++I + +++ F SV EI+ LL G L++ + + R + +
Sbjct: 642 ECNFTSDDQILQF-SSICFDASVQEIFSCLLSGAILVLRTEDMLRSSEDFWQYCQKWQLT 700
Query: 196 VL-VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY-KLAN 253
VL PT L+ A + + +KL + GE + ++ + N +L N
Sbjct: 701 VLSFPTAYWHQLVSELTPTALQIITNIKLIMVGGEAIQPSKVKQWHQNTVNYSPLPQLFN 760
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE T +PIGRPL N +Y+LD L P GE+ +
Sbjct: 761 AYGPTEATIITTLCKFTSPT----ITNVPIGRPLSNTQVYILDAFLQPVPVGVAGELHIG 816
Query: 314 GANLAAGYVGGG--GANRFCDNP------------HATQPEFQRLYRTGDF-GTLVKGAV 358
GA LA GY+ +F NP + E +LY+TGD L G +
Sbjct: 817 GAGLARGYLNRPELTQEKFIPNPFDEEGLIPPNPINKGSNESSKLYKTGDLCRYLPDGNI 876
Query: 359 LYAGRTDAQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR 418
Y GR D QVKIRG R++L E+E L+Q V +V+ + ++ ++ + G
Sbjct: 877 EYLGRIDNQVKIRGFRIELGEIETILSQHSAVKTAIVIAREDETEQKRLVAYIVPQEGIS 936
Query: 419 T-------SAQHIEGKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
+ + L++ L YM+P + +ES+PL NGKVDR+ L
Sbjct: 937 NRQEQGLLAVTELRQFLKAQLPEYMVPSAFVILESLPLTSNGKVDRRAL 985
Score = 140 bits (340), Expect = 1e-31
Identities = 119/391 (30%), Positives = 180/391 (46%), Gaps = 34/391 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ L+ KAG AY+P++P +PQ R+ +L+D++ L++ S + G F
Sbjct: 3749 IVTLIGILKAGGAYLPLDPEYPQARLQFMLEDSQIPLLLTQHSLIDKLPNHQGQTL--FL 3806
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
E E T+ +P A +T ++A V+YTSGSTG PKGV + + +CN Q
Sbjct: 3807 EEIWEKTA----QPSQDNLTAKVTPSNLANVIYTSGSTGKPKGVMVEHKGLCNLAQAQIE 3862
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLVLVP 199
T S + + + +F + EI L G L + ++E L+ R +
Sbjct: 3863 TLGVHPSSRVLQF-ASFSFDACIWEILMALGAGATLYLGTKEALMPGLPLMERLRDHAI- 3920
Query: 200 TLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGSTE 259
T + LA+ P L L+ + +GE S EL ++ G N YG TE
Sbjct: 3921 THITLPPSALAVLPWEN-LPSLQTIIVAGEACSPELVKKW------SQGRNFFNGYGPTE 3973
Query: 260 VMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANLAA 319
G V + + + I IGRP+ N +Y+LD L PGE+ + GA LA
Sbjct: 3974 --GSVCTAIAKCT---PFDEKITIGRPIPNVQVYILDPHLQAVPIGVPGELHIGGAGLAR 4028
Query: 320 GYVGGG--GANRFCDNPHAT-QPEF----------QRLYRTGDFGT-LVKGAVLYAGRTD 365
GY+ A +F NP + P +LY+TGD L G + Y GR D
Sbjct: 4029 GYLNRPELTAEKFISNPFVSLDPPLTPLDKGGEQPSKLYKTGDLARYLPDGQIEYLGRID 4088
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVL 396
QVK+RG R++L E+E L Q P V + +V+
Sbjct: 4089 NQVKVRGFRIELGEIEAVLGQHPLVQEAIVI 4119
>UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 3021
Score = 184 bits (448), Expect = 8e-45
Identities = 148/453 (32%), Positives = 219/453 (48%), Gaps = 29/453 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFK-ESGVPFASF 78
++ LLA K GAAYVP +P++P R+ + DA PSL++ + + +P
Sbjct: 1163 VIGLLAILKTGAAYVPFDPAYPAERLAFMFADAAPSLLLTQTALRAGLPPLPDTLPICCL 1222
Query: 79 EELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQF 138
+ AQ + +S P P++ ++A VLYTSGSTG PKGV S +A+ N + WQ
Sbjct: 1223 DVQAQRWSGYSEANPQ-----VPVSPGNLAYVLYTSGSTGRPKGVAHSRAALDNLIAWQL 1277
Query: 139 RTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------VNI 192
P S + +L F S EI L G +L+++S +D L +
Sbjct: 1278 EQTPVSQR---VLQFASLNFDVSFQEICSTLCQGGSLVLMSEAGRKDLAALRPTLVAEGV 1334
Query: 193 ERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELA--SEFFKYFGNEDGYK 250
+R L +L+ + + AS P+ L C T + L E + G +
Sbjct: 1335 QRAFLPFAVLQQLASFTETD-ASVPMP-LPKGGCEVITAGEALLVNDELRAFVCGLGGAQ 1392
Query: 251 LANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEV 310
L N YG TE V+ + L D PIGRP+ N +Y+LD +L+P GE+
Sbjct: 1393 LHNQYGPTETHV-VSQFSLNCDDAGQWPDAPPIGRPIANARLYVLDGDLNPVPVGVAGEL 1451
Query: 311 WVAGANLAAGYVGGG--GANRFCDNPHATQPEFQRLYRTGDFGTLVK-GAVLYAGRTDAQ 367
++AGA LA GY+ A RF +P Q R+YR+GD G V Y GR D Q
Sbjct: 1452 YIAGACLARGYLNRPDLSAERFLPDPFNPQSG-ARMYRSGDLARFAADGNVHYLGRIDQQ 1510
Query: 368 VKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGK 427
VK+RG RV+L E++ L Q PGV + VVL G+ ++ +V G T A+ + +
Sbjct: 1511 VKLRGFRVELGEIDSLLHQQPGVREAVVLLREDVPGDKRLVAYVV---GPAT-AETLRAE 1566
Query: 428 LRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
L L +M+P + + +PL NGK+DRQ L
Sbjct: 1567 LHRHLPEHMVPTAWVALAQLPLTRNGKLDRQAL 1599
Score = 175 bits (425), Expect = 5e-42
Identities = 157/560 (28%), Positives = 249/560 (44%), Gaps = 41/560 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ +LA KAG AYVP++P++P+ R+ H+L D+ P +++ A ++ + +
Sbjct: 89 LVGVLAVLKAGGAYVPLDPAYPKARLAHMLADSAPRVLLSHAPARAALLAALEEGEVATQ 148
Query: 80 ELAQEATSHSADEPM---DAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSA-ICNRLW 135
L T A +P D + LTS +A V+YTSGSTG+PKGV + + I
Sbjct: 149 VLDLTDTRLWAAQPTHNPDPHAVG-LTSRHLAYVIYTSGSTGMPKGVMVEHRGLIAVSAA 207
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL------ 189
W+ ++ + + +F ++ L G L++ R+T DP L
Sbjct: 208 WEPLYALHNPLNHLQM--AGFSFDVFSADLIRALGFGGTLVLCPRDTLMDPPALYRLLSE 265
Query: 190 VNIERLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGY 249
I+ VP +L +L++ A R L + VC + + A + G +
Sbjct: 266 ARIDFADFVPAVLNPLLVWAQ--EAGRDLSFMSTVVCGSDIWTAHSARQLRGLCGEQT-- 321
Query: 250 KLANFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGE 309
++ YG TE D T + E +D +PIGR L N IYLLD GE
Sbjct: 322 QIVQAYGVTEASIDSTCFEFEPDSHVDA--VLPIGRALANTRIYLLDAAGDRVPQGVTGE 379
Query: 310 VWVAGANLAAGYVGGGGANR--FCDNPHATQPEFQRLYRTGDFGTL-VKGAVLYAGRTDA 366
+++ GA +A GY+ R F D+P RLYRTGD G + + GR D+
Sbjct: 380 LYIGGAGVARGYLNLPELTRERFIDSPFVAG---DRLYRTGDLARYRADGHLEFLGRNDS 436
Query: 367 QVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEG 426
Q K+RG R++L E+E LA+V GV VV+ G P ++ + + GA + + +
Sbjct: 437 QAKLRGLRLELGEIEARLAEVAGVRDNVVVLREDGAGVPRLIAYFREQTGAALTPKGLRQ 496
Query: 427 KLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXX 485
L+ +L YM+P + ++++PL NGK+DR L DDA D
Sbjct: 497 HLQLSLPDYMIPAAFVRMDALPLTANGKLDRIAL------PEPGDDA-----FDRHVFEA 545
Query: 486 XXXXXXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRDRGYY-VEISD 544
VLG G + F+ LGG+SL + + K+R + V S
Sbjct: 546 AQGALEVSLAAIWAEVLGVERVGR---QDHFFALGGHSLLVMRVLAKVRQTLHLEVSPSA 602
Query: 545 FLGASTLGEVLSKMSTDPNG 564
A L + ++ST G
Sbjct: 603 LFTAPVLQQFAERLSTARQG 622
Score = 172 bits (419), Expect = 3e-41
Identities = 140/448 (31%), Positives = 213/448 (47%), Gaps = 21/448 (4%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A LA AG AY+P++P+ P R+ HIL+ AE SL + + + + V S
Sbjct: 2227 VVATLAIQYAGGAYLPLDPALPVERLEHILQRAEASLALTQPALLQRVEWPAQVQVISVS 2286
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ S ++A L P D +A V+YTSGSTG+PKGV + + N L R
Sbjct: 2287 DSIIADAGRSDQAELNAVHLTP---DDLAYVIYTSGSTGMPKGVVIDHRGAVNTLLDINR 2343
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK-LVNIERLVL- 197
F ++ + ++L+F SV + +G L G A+++L + DP L IER +
Sbjct: 2344 RFAVGAADRVLA-VSSLSFDLSVYDFFGTLAAGAAVVLLEPQQALDPAHWLTLIERHQVS 2402
Query: 198 ----VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
VP L +L Y+ + P L++ + SG+ + L + + + +L +
Sbjct: 2403 LWNSVPALFGMLLEYVQSERSVLPTC-LRVAMLSGDWIPLTLPE---RAWALQPALQLVS 2458
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
G+TE Y L+ D + +IP G+ LD+ Y+LD+ L G++++
Sbjct: 2459 LGGATEASIWSIQYPLQQVDPA--WRSIPYGKALDHQRFYVLDDALQVRPTWVAGQLYIG 2516
Query: 314 GANLAAGYVGGGGANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRG 372
G LA GY + H E RLYRTGD G L G + + GR D QVK++G
Sbjct: 2517 GIGLAKGYWRDEALSAGSFFAHPLTGE--RLYRTGDLGRWLPDGNIEFLGREDTQVKVQG 2574
Query: 373 HRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSAL 432
HR++L E+E AL + PGV VV G G + G+V K A L L
Sbjct: 2575 HRIELGEIEAALNRHPGVQSAVVRVLGEALGEKRLAGYV-LKADPSLQASDFVQYLADKL 2633
Query: 433 THYMMPQVIE-VESIPLLVNGKVDRQGL 459
YM+P V+ PL NGKVD++ L
Sbjct: 2634 PAYMLPTSFTFVQEWPLSANGKVDKKRL 2661
>UniRef50_A4XD41 Cluster: Amino acid adenylation domain precursor;
n=3; Salinispora|Rep: Amino acid adenylation domain
precursor - Salinispora tropica CNB-440
Length = 1726
Score = 184 bits (448), Expect = 8e-45
Identities = 162/557 (29%), Positives = 256/557 (45%), Gaps = 45/557 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
+ ALLA W+AG Y+P++ + P GR+ +L DA P V+ D A S+ ++ + +
Sbjct: 1164 VAALLAVWRAGGGYLPLDQNLPVGRLATMLADAAPP-VLLTDPAGMSLIGDA-IAVSGTT 1221
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ +D P D + DS+A +LYTSGSTG PKGV +++ A+ N L R
Sbjct: 1222 PVVLRVDQLDSDLPTDPPPVVGHL-DSLAYLLYTSGSTGAPKGVAVTHRAVINLLVGCHR 1280
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKL--VNIERLVL 197
F + + + T F S+ E+ PLL G + +L T +D L ++R V
Sbjct: 1281 LFELTADDRVAAITTP-AFDISLVELVLPLLAGARVEVLEAATAQDAILLRAACVQRGVT 1339
Query: 198 VPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYGS 257
V L + + L A+ ++L + GE L+++LA DG ++ N YG
Sbjct: 1340 V--LQATPATWGMLVTAAGVPAGVRLRISGGEALARDLADAL-----RADGARVINGYGP 1392
Query: 258 TEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGANL 317
+E + ++ S +DL G PL N I LLD P D GE+ + G +
Sbjct: 1393 SETTVYSSAGLVGESGPVDL------GYPLANTRILLLDAAGQPVPDGVVGEIHIGGTGV 1446
Query: 318 AAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGHR 374
A GY G G A RF +P + P RLY TGD L G ++Y GR D QVK+RG R
Sbjct: 1447 ARGYHGDPGRTAARFRPDPFSPTPG-GRLYATGDLARRLPDGRLVYHGRADQQVKVRGFR 1505
Query: 375 VDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQ---HIEGKLRSA 431
++L E+E AL PG+ VV +G D + + + T+P A A + L
Sbjct: 1506 IELGEIESALRDQPGIRDAVVTTWGAD-ADVRLAAYAVTEPAAVDPASIWPALRAGLARR 1564
Query: 432 LTHYMMPQVIEV-ESIPLLVNGKVDRQGLLK-MYENTNNNDDAEVAVDIDCSXXXXXXXX 489
L +M+P + V +++P +GK+DR+ L + + T + +
Sbjct: 1565 LPGHMVPATLVVLDALPRTASGKLDRRALAEPTWRETTGSGPTAPRTPAEAQLITLWQD- 1623
Query: 490 XXXXXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD-RGYYVEISDFLGA 548
VLGR G + F+ LGG+SL + I ++R G + + A
Sbjct: 1624 -----------VLGRTEVG---VHDNFFALGGHSLTATRLIARIRTVFGVELALRSLFAA 1669
Query: 549 STLGEVLSKMSTDPNGG 565
T+ E+ +++ + G
Sbjct: 1670 PTVAELAVQVAAADSHG 1686
Score = 147 bits (355), Expect = 2e-33
Identities = 140/450 (31%), Positives = 208/450 (46%), Gaps = 38/450 (8%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++ LLA KAG AY+P++P+ P RI +L A DP P + +
Sbjct: 87 VVTLLAVLKAGGAYLPLDPADPPARIRQLLAVA----------GDP--------PVLATD 128
Query: 80 ELAQEATSHSADEPMDAET--LAP--LTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLW 135
EL+ DEP A T +AP L D +A V +TSGSTG PKGV +++SA+ RL
Sbjct: 129 ELSGARRLFRLDEPGPAATTGVAPRRLHPDGLAYVNFTSGSTGAPKGVAVAHSAVV-RLV 187
Query: 136 WQFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERL 195
Q +E + + + F + EIWG L G A L+L+ + +L + R
Sbjct: 188 HQPGYLRLGPTETV-LQLAPVAFDAATLEIWGALSTG-ARLVLAPPGVLELAELARLLRR 245
Query: 196 VLVPTL-LRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANF 254
+ L L + L + + L + + G+ L+ E + + DG L N
Sbjct: 246 ERITVLWLTAGLFHQLVEFDPDCLTGVGQLLAGGDVLAPEAVRQALR---ARDGAVLING 302
Query: 255 YGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAG 314
YG TE Y + +D + +PIGRP+ ++Y+LD GE++ G
Sbjct: 303 YGPTENTTFTCVYPM--TDPEAVPDPVPIGRPVPRSSVYVLDPAGQQVPVGVAGELYTGG 360
Query: 315 ANLAAGYVG--GGGANRFCDNPHATQPEFQRLYRTGD-FGTLVKGAVLYAGRTDAQVKIR 371
A +A GY+G G A F +P +P R+YRTGD G + + GR D QVKIR
Sbjct: 361 AGVARGYLGRPGATAAAFLPDPFDPRPG-SRMYRTGDRVRWRPDGNLDFLGRIDDQVKIR 419
Query: 372 GHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGAR--TSAQHIEGKLR 429
G RV+ EV AL P V V+ G + +L ++T +PGA TS + E
Sbjct: 420 GFRVEPGEVAAALRAHPAVADAAVVVDG-EGERRRLLAYLTPRPGASAPTSRELAEYAAD 478
Query: 430 SALTHYMMPQVIEVESIPLLVNGKVDRQGL 459
H + + S+PL +GK+DR+ L
Sbjct: 479 RLPAHLRPGAYLVLPSLPLTPSGKIDRRAL 508
>UniRef50_UPI000038CDA7 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1075
Score = 184 bits (447), Expect = 1e-44
Identities = 140/455 (30%), Positives = 220/455 (48%), Gaps = 31/455 (6%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
I+ LL KAG AY+P++P+ + I L++ + +++ + +P + +
Sbjct: 519 IIGLLGILKAGGAYLPLDPTLTKDGIAGRLQNTQIPVILTQQRL------VNALPTHTAQ 572
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
+ + + + D + +T++++A VL+TSGSTG PKGV + + + N L +
Sbjct: 573 IVCLDTDWDTIAQHKDENLSSEVTTENLAYVLFTSGSTGKPKGVAIEHQQLLNYLNGITQ 632
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVN------IE 193
S + T + + I+ L G L +LS E D L I+
Sbjct: 633 RLDLSTTTNFATVSTLAADLGNT-GIFAALCTGGCLHVLSAECATDSAALAKYCRTHPID 691
Query: 194 RLVLVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLAN 253
L +VP+ L ++L A P+ L R +L + GE + +L + + + + N
Sbjct: 692 CLKIVPSHLATLL---AAAPSDSILPRQQL-ILGGEAANWQLIEQIQQQVPSS---LIFN 744
Query: 254 FYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVA 313
YG TE VT + +E Q++ T+P+GRPL N IYLLDE+L P PGE+++
Sbjct: 745 HYGPTEATVGVTTFAVE--QQINHTQTVPLGRPLANTQIYLLDEQLQPVPVGVPGELYIG 802
Query: 314 GANLAAGYVGGGG--ANRFCDNPHA-----TQPEFQRLYRTGDFGT-LVKGAVLYAGRTD 365
GA LA GY+ A +F NP A RLY+TGD L G + + GR D
Sbjct: 803 GAGLARGYLNQSDLTAAQFIPNPFADTGLIASKPGSRLYKTGDLARYLPDGNIEFLGRVD 862
Query: 366 AQVKIRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIE 425
QVKIRG R++L E+E L Q P V + V + GN ++ +V K S +
Sbjct: 863 HQVKIRGFRIELGEIETTLCQHPQVQQAVASIREEEFGNKSLVAYVVPKQQQTLSVSELY 922
Query: 426 GKLRSALTHYMMPQV-IEVESIPLLVNGKVDRQGL 459
LR L YMMP I ++++PL NGKV+R+ L
Sbjct: 923 RFLREKLPEYMMPATFIMLKALPLTPNGKVNRREL 957
>UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 3292
Score = 184 bits (447), Expect = 1e-44
Identities = 147/452 (32%), Positives = 225/452 (49%), Gaps = 32/452 (7%)
Query: 20 IMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFASFE 79
++A+L KAG AYVP++P F R +L D+E + + ++ + F GV + E
Sbjct: 1220 LIAVLGILKAGGAYVPLDPEFSNARRADVLVDSEARIAV-TRASHAAFFASLGVTVVTVE 1278
Query: 80 ELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFR 139
AQE T H + P A +T +++A V+YTSGSTG PKGV +S+ A+ + + +
Sbjct: 1279 --AQE-TRH--EPPPSA-----VTPENLAYVIYTSGSTGRPKGVMVSHRALASLVQAERV 1328
Query: 140 TFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQK--LVNIER--- 194
F + I + + L+F SV EI+ L G A L+L D + L ER
Sbjct: 1329 RFGVVPEDRILQFNS-LSFDSSVEEIFLALCTG-ATLVLRDAAMLDTVEGFLAGCERWAV 1386
Query: 195 -LVLVPT-LLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLA 252
L+ +PT +++ +A + P L+ + +GE + + +++ ++ L
Sbjct: 1387 TLLDLPTAFFHTVVAAMAERGLTLPAS-LRFVIVAGERVRADRVTQWHRHA--PPSIHLI 1443
Query: 253 NFYGSTEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWV 312
N YG TE T + L + L +PIG+PL Y+LD L P GE+W+
Sbjct: 1444 NVYGPTEATVSATCHDLSAATTTGL-DDVPIGQPLRTMGAYVLDGRLEPVPAGGVGELWL 1502
Query: 313 AGANLAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGTLVKGAVL-YAGRTDAQVK 369
G LA GY A RF +PHAT P R+YRTGD + VL Y GR D QVK
Sbjct: 1503 TGEGLARGYFRDPALTAERFMADPHATTPG-SRIYRTGDLARMRADGVLEYLGRADDQVK 1561
Query: 370 IRGHRVDLLEVERALAQVPGVDKCVVLCYGLDRG-NPEILGFVTTKPGARTSAQHIEGKL 428
+RG RV+L E+E AL GV +VL +G + G ++ + P SA + +L
Sbjct: 1562 VRGFRVELGEIETALRACEGVRDAIVLLHGENAGKEARLIAYAVAAPEVAPSA--LRAQL 1619
Query: 429 RSALTHYMMP-QVIEVESIPLLVNGKVDRQGL 459
+ L YM+P ++ + + P +GKVDR+ L
Sbjct: 1620 AARLPPYMVPAAIVRLAAFPYGSSGKVDRRAL 1651
Score = 179 bits (436), Expect = 2e-43
Identities = 141/523 (26%), Positives = 240/523 (45%), Gaps = 31/523 (5%)
Query: 17 FSTIMALLATWKAGAAYVPMEPSFPQGRITHILKDAEPSLVIYDDSADPSMFKESGVPFA 76
F ++ +L KAG AY+P+EP P+ R+T +L DA+ LV+ +++ +P++ G+
Sbjct: 2275 FERVIGMLGILKAGGAYLPLEPGHPRERLTRMLTDADARLVLTEEALEPTL---EGI--- 2328
Query: 77 SFEELAQEATSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWW 136
+ L +A S ++++A V+YTSGSTG PKGV + + A+ +
Sbjct: 2329 LADRLCLDAGWSSIAGESAGGVPDAAGAENLAYVMYTSGSTGQPKGVCIPHRAVVRLV-- 2386
Query: 137 QFRTFPYSDSEEICVWKTALTFVDSVCEIWGPLLHGRALLILSRETTRDPQKLVNIERLV 196
+ +E+ + +F + E+WGPLL+G L++ + T + + R
Sbjct: 2387 TAPNYVTLSAEDAFLHLAPFSFDAATLELWGPLLNGGRLVLFPGDGTSLERLEDTLARHR 2446
Query: 197 LVPTLLRSILMYLALGPASRPLRRLKLWVCSGETLSKELASEFFKYFGNEDGYKLANFYG 256
+ L + L + + L ++ + G+ LS + + G +L N YG
Sbjct: 2447 VTTLWLTAGLFHNVVEHHLEALSGVRQLLAGGDVLS---PTHVRRVLERPPGLRLINGYG 2503
Query: 257 STEVMGDVTYYVLEGSDQLDLYPTIPIGRPLDNCAIYLLDEELSPTRDSEPGEVWVAGAN 316
TE + +E D+ +PIG P+ ++LLD L P PGE++ AG
Sbjct: 2504 PTENTTFTCCHPMEALDEAT--APVPIGAPVTGTRVHLLDAGLEPVPLGAPGELYCAGDG 2561
Query: 317 LAAGYVGGGG--ANRFCDNPHATQPEFQRLYRTGDFGT-LVKGAVLYAGRTDAQVKIRGH 373
LA GY+G A RF +P + +P R+YRTGD G++ + GR D QVK+RG
Sbjct: 2562 LARGYMGHADLTAERFLPDPFSRKPG-SRMYRTGDLACWRADGSIEFLGRVDNQVKVRGF 2620
Query: 374 RVDLLEVERALAQVPGVDKCVVLCYGLDRGNPEILGFVTTKPGARTSAQHIEGKLRSALT 433
R++ EVE L + P V V+ G ++ V + + ++ + L L
Sbjct: 2621 RIEPGEVEATLLRHPAVRDAAVVAAGERADTKRLVAHVVLRDASAITSGDLRDYLEPQLP 2680
Query: 434 HYMMPQ-VIEVESIPLLVNGKVDRQGLLKMYENTNNNDDAEVAVDIDCSXXXXXXXXXXX 492
+M+P V+ ++PL NGKVDR+ L + D E +
Sbjct: 2681 EHMIPSAVVFHHALPLSPNGKVDRRVLAQA-----PLDSPEAGGPLSAPRTAAELTLVSL 2735
Query: 493 XXXXTVGAVLGRAARGTLSLRSGFYELGGNSLNSIYTITKLRD 535
+LGR G + F+ELGG+SL + ++++R+
Sbjct: 2736 WR-----ELLGRTHVG---IHENFFELGGHSLLATRLLSRVRE 2770
Score = 51.2 bits (117), Expect = 1e-04
Identities = 30/94 (31%), Positives = 45/94 (47%)
Query: 86 TSHSADEPMDAETLAPLTSDSIAIVLYTSGSTGIPKGVRLSYSAICNRLWWQFRTFPYSD 145
T D DA T PL+ DS+A + YTSGST +PKGV L++ + + L R F
Sbjct: 148 TDEVDDRASDAWTPPPLSGDSLAFLQYTSGSTSLPKGVTLTHRNLLHNLEAIRRCFRQDQ 207
Query: 146 SEEICVWKTALTFVDSVCEIWGPLLHGRALLILS 179
+ +W + + I PL G +++S
Sbjct: 208 TSRAIIWLPPYHDMGLIGGILQPLYTGYPAVLMS 241
Score = 48.0 bits (109), Expect = 0.001
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 9/188 (4%)
Query: 278 YPTIPIGRPLDNCAIYLLDEE-LSPTRDSEPGEVWVAGANLAAGYVGGGGANRFCDNPHA 336
+P + GR + + + ++D E RD E GE+WV+G+++A GY G A
Sbjct: 371 HPLVGSGRNVIDGRLAVVDPETFELRRDGEIGEIWVSGSSVAGGYWGQPEATTRTFQARL 430
Query: 337 TQPEFQRLYRTGDFGTLVKGAVLYAGRTDAQVKIRGHRVDLLEVERALAQV-PGVDKCVV 395
RTGD G L G + GR + IRG ++E + + P V
Sbjct: 431 RGTGEGPFLRTGDLGFLRDGELFVTGRAKDLIIIRGLNHFPQDIEFTVEKCHPAVRPGSG 490
Query: 396 LCYGLDRGNPE--ILGFVTTKPGARTSAQHIEGKLRSALT--HYMMPQ---VIEVESIPL 448
+ ++ E ++ + A + + +R + H +M +IE S+P
Sbjct: 491 AAFSVEADGTEQLVVVYEANAQRAESGLDEVISAIRRTVAEQHELMASSVVLIEPGSVPK 550
Query: 449 LVNGKVDR 456
+GK+ R
Sbjct: 551 TSSGKIQR 558
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.136 0.407
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 871,988,872
Number of Sequences: 1657284
Number of extensions: 37419221
Number of successful extensions: 100741
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1531
Number of HSP's successfully gapped in prelim test: 1136
Number of HSP's that attempted gapping in prelim test: 86844
Number of HSP's gapped (non-prelim): 7188
length of query: 783
length of database: 575,637,011
effective HSP length: 107
effective length of query: 676
effective length of database: 398,307,623
effective search space: 269255953148
effective search space used: 269255953148
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 76 (34.7 bits)
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