BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000012-TA|BGIBMGA000012-PA|IPR012464|Protein of unknown function DUF1676, IPR000005|Helix-turn-helix, AraC type (497 letters) Database: fruitfly 52,641 sequences; 24,830,863 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AE014297-421|AAF51900.1| 233|Drosophila melanogaster CG15592-PA... 81 3e-15 AY070617-1|AAL48088.1| 233|Drosophila melanogaster RE71995p pro... 80 8e-15 BT016007-1|AAV36892.1| 288|Drosophila melanogaster RE26656p pro... 60 9e-09 AE014297-419|AAF51902.1| 288|Drosophila melanogaster CG1153-PA ... 60 9e-09 BT009951-1|AAQ22420.1| 295|Drosophila melanogaster RH51767p pro... 47 7e-05 AE014297-425|AAF51897.2| 295|Drosophila melanogaster CG1154-PA ... 47 7e-05 AE014297-420|AAF51901.1| 274|Drosophila melanogaster CG15591-PA... 43 0.001 AE014297-432|AAN13237.1| 278|Drosophila melanogaster CG31561-PA... 42 0.001 AF132170-1|AAD34758.1| 286|Drosophila melanogaster unknown prot... 40 0.010 AE014297-418|AAF51903.2| 312|Drosophila melanogaster CG1151-PA ... 40 0.010 AE014134-2062|AAF53094.1| 282|Drosophila melanogaster CG14925-P... 31 4.8 AE014297-4594|AAF57047.2| 250|Drosophila melanogaster CG15538-P... 30 6.4 AE014296-852|AAF47904.2| 242|Drosophila melanogaster CG11345-PA... 30 6.4 AY119041-1|AAM50901.1| 393|Drosophila melanogaster LP06455p pro... 30 8.4 AE014297-416|AAF51905.3| 393|Drosophila melanogaster CG10303-PA... 30 8.4 >AE014297-421|AAF51900.1| 233|Drosophila melanogaster CG15592-PA protein. Length = 233 Score = 81.4 bits (192), Expect = 3e-15 Identities = 62/244 (25%), Positives = 110/244 (45%), Gaps = 17/244 (6%) Query: 1 MLKYIALLALTASVQCNPLKENSISENLVGVISECIERDTSLCIKEKALKFTERLAFSKD 60 M K++ L AL AS + +S+ + + ++ +C ER LC+KE+AL + + A + D Sbjct: 1 MFKFVCLFALIASTAAATSEADSLLTSALKMVKDCGERSMVLCMKERALHYFD--AENGD 58 Query: 61 MNIFDGMSLVNIGSARSARSYE--PLAEDPKARELQLDERIADNMGDFLENHVIQLRLSE 118 + + +G++LV RS L E+ +ARE ++D + + + F H +Q ++ + Sbjct: 59 VRLTEGIALVKTDEIPVGRSLNEMQLPEEVEAREAEVDSLLVERVARFFGTHTLQFKVPK 118 Query: 119 PEAE--SRSLDDEARGXXXXXXXXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKI 176 + R+L +E+RG G +A ++ KA+ +GKI Sbjct: 119 DSIQDMQRAL-EESRGKKKEKKKYLMPLLMLFKLKMAALLPLAIGFLALISFKALVIGKI 177 Query: 177 AFAMSAFQLIRKLLNKNQXXXXXXXXYAAPHHHEEHPGYSYEPASSGGWGRQATDAQSLA 236 A +S ++KLL + A PH+ EH P+ + AQ LA Sbjct: 178 ALLLSGIIGLKKLLESKK---ENYEVVAHPHYEHEHSYGRSLPSDD-------SQAQQLA 227 Query: 237 YAVH 240 YA + Sbjct: 228 YAAY 231 >AY070617-1|AAL48088.1| 233|Drosophila melanogaster RE71995p protein. Length = 233 Score = 79.8 bits (188), Expect = 8e-15 Identities = 61/244 (25%), Positives = 110/244 (45%), Gaps = 17/244 (6%) Query: 1 MLKYIALLALTASVQCNPLKENSISENLVGVISECIERDTSLCIKEKALKFTERLAFSKD 60 M +++ L AL AS + +S+ + + ++ +C ER LC+KE+AL + + A + D Sbjct: 1 MFEFVCLFALIASTAAATSEADSLLTSALKMVKDCGERSMVLCMKERALHYFD--AENGD 58 Query: 61 MNIFDGMSLVNIGSARSARSYE--PLAEDPKARELQLDERIADNMGDFLENHVIQLRLSE 118 + + +G++LV RS L E+ +ARE ++D + + + F H +Q ++ + Sbjct: 59 VRLTEGIALVKTDEIPVGRSLNEMQLPEEVEAREAEVDSLLVERVARFFGTHTLQFKVPK 118 Query: 119 PEAE--SRSLDDEARGXXXXXXXXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKI 176 + R+L +E+RG G +A ++ KA+ +GKI Sbjct: 119 DSIQDMQRAL-EESRGKKKEKKKYLMPLLMLFKLKMAALLPLAIGFLALISFKALVIGKI 177 Query: 177 AFAMSAFQLIRKLLNKNQXXXXXXXXYAAPHHHEEHPGYSYEPASSGGWGRQATDAQSLA 236 A +S ++KLL + A PH+ EH P+ + AQ LA Sbjct: 178 ALLLSGIIGLKKLLESKK---ENYEVVAHPHYEHEHSYGRSLPSDD-------SQAQQLA 227 Query: 237 YAVH 240 YA + Sbjct: 228 YAAY 231 >BT016007-1|AAV36892.1| 288|Drosophila melanogaster RE26656p protein. Length = 288 Score = 59.7 bits (138), Expect = 9e-09 Identities = 69/278 (24%), Positives = 115/278 (41%), Gaps = 53/278 (19%) Query: 5 IALLALTASVQCNPLK---ENSIS-ENLV--GVISECIERDTSLCIKEKALKFTERLAFS 58 + L+AL+A++ + N+I EN + + S+C+ +D+ C+K K F +++ + Sbjct: 11 LCLVALSAALPAEETRGHARNAIGGENDIMDSIYSDCLRKDSVSCVKYKLFSFVDKVLGA 70 Query: 59 KDM-NIFDGMSLVNIGSARSARSYEPLAEDPKARELQLDERIADNMGDFLENHVIQLRLS 117 +D + +G+++V A + ++ D L L+ + FL +H I++ L Sbjct: 71 RDQFALTEGVTVVRSPDAPQQEAARSISGDESFESLALNR-----ISSFLNSHTIKVELK 125 Query: 118 EPE------AESRSLDD---------------EARGXXXXXXXXXXXXXXXXXXXXXXXX 156 + + R+L+D E+RG Sbjct: 126 GADIVQAVSSTGRALEDASESLFGSNDPNAPEESRGKKKKAAKILGPILALVALKAAALL 185 Query: 157 XXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLNKNQXXXXXXXXYAAPHHHEEH---- 212 G IA +A KA+ +GKIA +SA ++KLL +Q A PHH H Sbjct: 186 PLLLGAIALIAGKALLIGKIALVLSAVIGLKKLL--SQEKHVTYEVVAHPHHSSSHSTSH 243 Query: 213 ----PGY---------SYEPASSGGWGRQATDAQSLAY 237 GY SY + GGWGR + DAQ LAY Sbjct: 244 DSYGSGYSADAGASSASYGSSGHGGWGR-SIDAQDLAY 280 >AE014297-419|AAF51902.1| 288|Drosophila melanogaster CG1153-PA protein. Length = 288 Score = 59.7 bits (138), Expect = 9e-09 Identities = 69/278 (24%), Positives = 115/278 (41%), Gaps = 53/278 (19%) Query: 5 IALLALTASVQCNPLK---ENSIS-ENLV--GVISECIERDTSLCIKEKALKFTERLAFS 58 + L+AL+A++ + N+I EN + + S+C+ +D+ C+K K F +++ + Sbjct: 11 LCLVALSAALPAEETRGHARNAIGGENDIMDSIYSDCLRKDSVSCVKYKLFSFVDKVLGA 70 Query: 59 KDM-NIFDGMSLVNIGSARSARSYEPLAEDPKARELQLDERIADNMGDFLENHVIQLRLS 117 +D + +G+++V A + ++ D L L+ + FL +H I++ L Sbjct: 71 RDQFALTEGVTVVRSPDAPQQEAARSISGDESFESLALNR-----ISSFLNSHTIKVELK 125 Query: 118 EPE------AESRSLDD---------------EARGXXXXXXXXXXXXXXXXXXXXXXXX 156 + + R+L+D E+RG Sbjct: 126 GADIVQAVSSTGRALEDASESLFGSNDPNAPEESRGKKKKAAKILGPILALVALKAAALL 185 Query: 157 XXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLNKNQXXXXXXXXYAAPHHHEEH---- 212 G IA +A KA+ +GKIA +SA ++KLL +Q A PHH H Sbjct: 186 PLLLGAIALIAGKALLIGKIALVLSAVIGLKKLL--SQEKHVTYEVVAHPHHSSSHSTSH 243 Query: 213 ----PGY---------SYEPASSGGWGRQATDAQSLAY 237 GY SY + GGWGR + DAQ LAY Sbjct: 244 DSYGSGYSADAGASSASYGSSGHGGWGR-SIDAQDLAY 280 >BT009951-1|AAQ22420.1| 295|Drosophila melanogaster RH51767p protein. Length = 295 Score = 46.8 bits (106), Expect = 7e-05 Identities = 51/226 (22%), Positives = 90/226 (39%), Gaps = 14/226 (6%) Query: 25 SENLVGVISECIERDTSL--CIKEKALKFTERLAFSKDMNIFDGMSLVNIGSA-RSARSY 81 + L+ V EC + C+K+KA+ F +RLA +N+ +G+ LV + +A R + Sbjct: 45 ARTLLRVYDECTRAEAGFVPCLKKKAISFIDRLAPIDAINVAEGIKLVRLETAPRPPATS 104 Query: 82 EPLAED--PKA---RELQLDERIADNMGDFLENHVIQLRLSEPEAESRSLDDEARGXXXX 136 E E P++ R+ +L + + + F H L++S P+ S + Sbjct: 105 ENELESSLPRSGSDRDAKLTNMLIERLSYFFNGH--SLQVSFPKLTSDEIGRGLEEGRGK 162 Query: 137 XXXXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLN-KNQX 195 G + +A KA+ + KIA ++ ++KL++ K+ Sbjct: 163 MKKMMGMMMMGMAMKMMGMIPIAMGALYILAGKALIISKIALLLAGIIGLKKLMSGKSSG 222 Query: 196 XXXXXXXYAAPHHHEEHPGYSYEPASSGGWGRQA-TDAQSLAYAVH 240 G GGW R++ T+AQ LAY H Sbjct: 223 GSSGWSSGGGGGGGGWSSGGG--GGGGGGWDRRSLTEAQELAYRAH 266 >AE014297-425|AAF51897.2| 295|Drosophila melanogaster CG1154-PA protein. Length = 295 Score = 46.8 bits (106), Expect = 7e-05 Identities = 51/226 (22%), Positives = 90/226 (39%), Gaps = 14/226 (6%) Query: 25 SENLVGVISECIERDTSL--CIKEKALKFTERLAFSKDMNIFDGMSLVNIGSA-RSARSY 81 + L+ V EC + C+K+KA+ F +RLA +N+ +G+ LV + +A R + Sbjct: 45 ARTLLRVYDECTRAEAGFVPCLKKKAISFIDRLAPIDAINVAEGIKLVRLETAPRPPATS 104 Query: 82 EPLAED--PKA---RELQLDERIADNMGDFLENHVIQLRLSEPEAESRSLDDEARGXXXX 136 E E P++ R+ +L + + + F H L++S P+ S + Sbjct: 105 ENELESSLPRSGSDRDAKLTNMLIERLSYFFNGH--SLQVSFPKLTSDEIGRGLEEGRGK 162 Query: 137 XXXXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLN-KNQX 195 G + +A KA+ + KIA ++ ++KL++ K+ Sbjct: 163 MKKMMGMMMMGMAMKMMGMIPIAMGALYILAGKALIISKIALLLAGIIGLKKLMSGKSSG 222 Query: 196 XXXXXXXYAAPHHHEEHPGYSYEPASSGGWGRQA-TDAQSLAYAVH 240 G GGW R++ T+AQ LAY H Sbjct: 223 GSSGWSSGGGGGGGGWSSGGG--GGGGGGWDRRSLTEAQELAYRAH 266 >AE014297-420|AAF51901.1| 274|Drosophila melanogaster CG15591-PA protein. Length = 274 Score = 42.7 bits (96), Expect = 0.001 Identities = 40/171 (23%), Positives = 76/171 (44%), Gaps = 17/171 (9%) Query: 31 VISECIERDTSLCIKEKALKFTERLAFS-KDMNIFDGMSLVNIGSARSARSYEPLAE-DP 88 + +C + S+C+K K L E+ S K +++ +G+ V+ G P++E D Sbjct: 64 IYQQCSGDNMSVCLKVKLLTGLEKAFRSAKSLSLMEGIQFVSSGGESEETKRAPISEKDI 123 Query: 89 KA---RELQLDERIADNM-----GDFLENHVIQLRLSEPEAESRSLDDEARGXXXXXXXX 140 +A R + E++ +NM G+FL++H +Q++ + EA S G Sbjct: 124 EAVLPRSVDAKEQVLNNMILKRVGNFLQDHTLQVKF-DNEANS------VEGRKKKEKKG 176 Query: 141 XXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLN 191 G +A +A KA+ + K+A +++ I+KLL+ Sbjct: 177 NGAMIMIPLLLGGTIVPLAYGALAMLAGKALIVSKLALVLASIIGIKKLLS 227 >AE014297-432|AAN13237.1| 278|Drosophila melanogaster CG31561-PA protein. Length = 278 Score = 42.3 bits (95), Expect = 0.001 Identities = 54/236 (22%), Positives = 91/236 (38%), Gaps = 19/236 (8%) Query: 24 ISENLVGVISECIERDTS-LCIKEKALKFTERLAFSKDMNIFDGMSLVNIGSARSARSYE 82 I + ++S C S +C+K + +K E+LA +++N+ G+S+V +A ++ E Sbjct: 43 IPQRAESLLSGCEASSFSWMCLKIEFVKIMEKLAEQEELNVLPGISVVKDENATELKTSE 102 Query: 83 PLAE----DPKARELQLDERIADNMGDFLENHVIQLRLSEPEAESRSLDDEARGXXXXXX 138 +AE P +L+ I + + L ++ RL + +SL E R Sbjct: 103 LMAEVARSYPSDPSTRLNGYIVAKLENLLRTRFLRFRL----LDDKSL-VEGRKHKFGKK 157 Query: 139 XXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLL----NKNQ 194 G IA +A KA+ +A +S ++ L Sbjct: 158 GGLEALVAAGVMMKGMLMAMGLGAIALMAGKALMTALMALTLSGVLGLKSLAGGGGKSTT 217 Query: 195 XXXXXXXXYAAPHHH---EEHPGYSYEP--ASSGGWGRQATDAQSLAYAVHLVFDQ 245 Y + H H E G+S+ P A+ GG G A+ YA L DQ Sbjct: 218 YEIVAKPIYTSSHSHSVTHEDGGHSHSPHFAAGGGGGGTASGFGYGGYARSLKVDQ 273 >AF132170-1|AAD34758.1| 286|Drosophila melanogaster unknown protein. Length = 286 Score = 39.5 bits (88), Expect = 0.010 Identities = 26/131 (19%), Positives = 57/131 (43%), Gaps = 9/131 (6%) Query: 7 LLALTASVQCNPLKENSISENLVGVISECIERDTSLCIKEKALKFTERLAFSKDMNIFDG 66 +L L A + +P+K +E G ++C+E D+ C++ + + + + + +F G Sbjct: 10 ILLLAAGISADPVKA---AEEQPGAFAQCLESDSISCLQLTLFRKAKSVFDNPQIELFGG 66 Query: 67 MSLVNIGSARSARSYE-----PLAEDPKARELQLDERIADNMGDFLENHVIQLRLSE-PE 120 +SLV R +S + A +AR ++ DN F + + Sbjct: 67 VSLVKSNEGRQGKSLDNSLAVEAAPTVEARTAEMGNYFMDNAKSFFAERSLNFNFANAAR 126 Query: 121 AESRSLDDEAR 131 + +R++ D+ + Sbjct: 127 SVARAIPDDIK 137 >AE014297-418|AAF51903.2| 312|Drosophila melanogaster CG1151-PA protein. Length = 312 Score = 39.5 bits (88), Expect = 0.010 Identities = 26/131 (19%), Positives = 57/131 (43%), Gaps = 9/131 (6%) Query: 7 LLALTASVQCNPLKENSISENLVGVISECIERDTSLCIKEKALKFTERLAFSKDMNIFDG 66 +L L A + +P+K +E G ++C+E D+ C++ + + + + + +F G Sbjct: 36 ILLLAAGISADPVKA---AEEQPGAFAQCLESDSISCLQLTLFRKAKSVFDNPQIELFGG 92 Query: 67 MSLVNIGSARSARSYE-----PLAEDPKARELQLDERIADNMGDFLENHVIQLRLSE-PE 120 +SLV R +S + A +AR ++ DN F + + Sbjct: 93 VSLVKSNEGRQGKSLDNSLAVEAAPTVEARTAEMGNYFMDNAKSFFAERSLNFNFANAAR 152 Query: 121 AESRSLDDEAR 131 + +R++ D+ + Sbjct: 153 SVARAIPDDIK 163 >AE014134-2062|AAF53094.1| 282|Drosophila melanogaster CG14925-PA protein. Length = 282 Score = 30.7 bits (66), Expect = 4.8 Identities = 30/182 (16%), Positives = 66/182 (36%), Gaps = 5/182 (2%) Query: 31 VISECIERDTSL-CIKEKALKFTERLAFSKDMNIFDGMSLVNIGSARSARSYEPLAEDPK 89 V +C +++ + C+K+KAL R + I DG++L + + L + + Sbjct: 57 VYDDCQDKNDFIGCLKQKALHALSRALDQDSIKIVDGLALEKQNQSETESILGSLTDARQ 116 Query: 90 ARELQ-LDERIADNMGDFLENHVIQLRLSEPEAESRSLDDEARGXXXXXXXXXXXXXXXX 148 L +D + + H +++ + E S+ E Sbjct: 117 FGNLSPIDRALLSKADKLMRTHTLKIDMDVGGGED-SVGREHGHKKKKHKEGGHIKYVVA 175 Query: 149 XXXXXXXXXXXXGI--IAFVAVKAVFLGKIAFAMSAFQLIRKLLNKNQXXXXXXXXYAAP 206 G+ +A +A KA+ + K+A ++ ++KL + + +A Sbjct: 176 ALLTAMGIAGPLGLKALAAIAGKALVISKVALTIAGIIALKKLFSHDHSEETSFQVHAGE 235 Query: 207 HH 208 H+ Sbjct: 236 HN 237 >AE014297-4594|AAF57047.2| 250|Drosophila melanogaster CG15538-PA protein. Length = 250 Score = 30.3 bits (65), Expect = 6.4 Identities = 17/76 (22%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Query: 43 CIKEKALKFTERLAFSKDMNIFDGMSLVNIGSARSARSYEPLAEDPKARELQLDERIADN 102 C + ++L E + S +++I+DG+ LV ++ + + P E + L +++A + Sbjct: 57 CFRSRSLHIFEGIMSSPEISIYDGVRLVAAPNS-TDNATRPDDERKDLKHLTWFDQLAVS 115 Query: 103 MGDFLENHVIQLRLSE 118 + L H +Q+ L + Sbjct: 116 LAKGLTTHTLQVNLGK 131 >AE014296-852|AAF47904.2| 242|Drosophila melanogaster CG11345-PA protein. Length = 242 Score = 30.3 bits (65), Expect = 6.4 Identities = 9/15 (60%), Positives = 12/15 (80%) Query: 207 HHHEEHPGYSYEPAS 221 H H +HPGY+Y+P S Sbjct: 27 HDHHDHPGYNYDPPS 41 >AY119041-1|AAM50901.1| 393|Drosophila melanogaster LP06455p protein. Length = 393 Score = 29.9 bits (64), Expect = 8.4 Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 163 IAFVAVKAVFLGKIAFAMSAFQLIRKLLN 191 + + +KA+ L KIAF ++A LI+KL++ Sbjct: 236 VGLLTLKALILSKIAFVVAAIVLIKKLMD 264 >AE014297-416|AAF51905.3| 393|Drosophila melanogaster CG10303-PA protein. Length = 393 Score = 29.9 bits (64), Expect = 8.4 Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 163 IAFVAVKAVFLGKIAFAMSAFQLIRKLLN 191 + + +KA+ L KIAF ++A LI+KL++ Sbjct: 236 VGLLTLKALILSKIAFVVAAIVLIKKLMD 264 Database: fruitfly Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 24,830,863 Number of sequences in database: 52,641 Lambda K H 0.316 0.132 0.381 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 17,038,604 Number of Sequences: 52641 Number of extensions: 575389 Number of successful extensions: 1983 Number of sequences better than 10.0: 15 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 1955 Number of HSP's gapped (non-prelim): 22 length of query: 497 length of database: 24,830,863 effective HSP length: 88 effective length of query: 409 effective length of database: 20,198,455 effective search space: 8261168095 effective search space used: 8261168095 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 64 (29.9 bits)
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