Silkworm BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000004-TA|BGIBMGA000004-PA|IPR001128|Cytochrome P450,
IPR002401|E-class P450, group I
         (311 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC060857-1|AAH60857.1|  525|Homo sapiens cytochrome P450, family...   174   4e-43
AY422002-1|AAR31180.1|  525|Homo sapiens cytochrome P450 4V2 pro...   174   4e-43
AK126473-1|BAC86562.1|  503|Homo sapiens protein ( Homo sapiens ...   174   4e-43
AK122600-1|BAC85487.1|  525|Homo sapiens protein ( Homo sapiens ...   174   4e-43
U02388-1|AAC50052.2|  520|Homo sapiens cytochrome P450 4F2 protein.   144   3e-34
BC067440-1|AAH67440.1|  520|Homo sapiens cytochrome P450, family...   143   8e-34
AB015306-1|BAA75823.1|  520|Homo sapiens Leukotriene B4 omega-hy...   143   8e-34
D26480-1|BAA05490.1|  520|Homo sapiens leukotriene B4 omega-hydr...   142   1e-33
BC067439-1|AAH67439.1|  520|Homo sapiens cytochrome P450, family...   142   1e-33
BC067437-1|AAH67437.1|  520|Homo sapiens cytochrome P450, family...   142   1e-33
AF467894-1|AAL67578.1|  520|Homo sapiens cytochrome P450, subfam...   142   1e-33
AC005336-1|AAC27730.1|  520|Homo sapiens CYP4F2 protein.              142   1e-33
AY792513-1|AAV40834.1|  520|Homo sapiens cytochrome P450, family...   139   1e-32
AF054821-1|AAC08589.1|  520|Homo sapiens cytochrome P-450 protein.    139   1e-32
BC028102-1|AAH28102.1|  509|Homo sapiens cytochrome P450, family...   137   4e-32
AY358537-1|AAQ88901.1|  509|Homo sapiens EFSW1929 protein.            137   4e-32
AM040940-1|CAJ13826.1|  509|Homo sapiens cytochrome P450 protein.     137   4e-32
AL450996-1|CAH71035.1|  509|Homo sapiens cytochrome P450, family...   137   4e-32
AK131355-1|BAD18508.1|  508|Homo sapiens protein ( Homo sapiens ...   137   4e-32
AK098065-1|BAC05226.1|  509|Homo sapiens protein ( Homo sapiens ...   137   4e-32
AK091806-1|BAC03751.1|  444|Homo sapiens protein ( Homo sapiens ...   137   4e-32
D12620-1|BAA02144.1|  520|Homo sapiens cytochrome P-450LTBV prot...   136   9e-32
BC035350-1|AAH35350.1|  524|Homo sapiens cytochrome P450, family...   136   9e-32
AY358977-1|AAQ89336.1|  524|Homo sapiens CYP4F12 protein.             136   9e-32
AY008841-1|AAG33247.1|  524|Homo sapiens cytochrome P450 isoform...   136   9e-32
AC004523-1|AAC11543.1|  458|Homo sapiens F22329_1 protein.            136   9e-32
AB035131-1|BAB18270.1|  524|Homo sapiens cytochrome P450 protein.     136   9e-32
AB035130-1|BAB18269.1|  524|Homo sapiens cytochrome P450 protein.     136   9e-32
AB002461-1|BAA25991.1|  520|Homo sapiens leukotriene B4 omega-hy...   136   9e-32
AB002454-1|BAA25990.1|  520|Homo sapiens leukotriene B4 omega-hy...   136   9e-32
AF133298-1|AAD49566.1|  520|Homo sapiens cytochrome P450 protein.     132   1e-30
BC016853-1|AAH16853.1|  524|Homo sapiens CYP4F11 protein protein.     131   3e-30
AF236085-1|AAG15889.1|  524|Homo sapiens CYP4F11 protein.             128   2e-29
X16699-1|CAA34672.1|  511|Homo sapiens protein ( Human mRNA for ...   121   4e-27
J02871-1|AAA35712.1|  511|Homo sapiens protein ( Human lung cyto...   121   4e-27
DQ518907-1|ABF47106.1|  511|Homo sapiens cytochrome P450, family...   121   4e-27
BC017758-1|AAH17758.1|  512|Homo sapiens cytochrome P450, family...   121   4e-27
AY151049-1|AAN72312.1|  497|Homo sapiens pulmonary cytochrome P4...   121   4e-27
AY151048-1|AAN72311.1|  512|Homo sapiens pulmonary cytochrome P4...   121   4e-27
AY064485-1|AAL57720.1|  511|Homo sapiens cytochrome P450 protein.     121   4e-27
AL593856-7|CAI16983.1|  497|Homo sapiens cytochrome P450, family...   121   4e-27
AL593856-6|CAI16982.1|  512|Homo sapiens cytochrome P450, family...   121   4e-27
AL593856-5|CAI16981.1|  511|Homo sapiens cytochrome P450, family...   121   4e-27
AL356793-4|CAI22559.1|  511|Homo sapiens cytochrome P450, family...   121   4e-27
AL356793-3|CAI22557.1|  512|Homo sapiens cytochrome P450, family...   121   4e-27
AL356793-2|CAI22558.1|  497|Homo sapiens cytochrome P450, family...   121   4e-27
AF491285-1|AAM09532.1|  511|Homo sapiens cytochrome P450 protein.     121   4e-27
BC093896-1|AAH93896.1|  531|Homo sapiens cytochrome P450, family...   120   5e-27
BC093894-1|AAH93894.1|  531|Homo sapiens cytochrome P450, family...   120   5e-27
BC069351-1|AAH69351.1|  531|Homo sapiens cytochrome P450, family...   120   5e-27
AY064486-1|AAL57721.1|  511|Homo sapiens cytochrome P450 protein.     120   9e-27
AK096820-1|BAC04868.1|  531|Homo sapiens protein ( Homo sapiens ...   119   2e-26
S67580-1|AAB29502.1|  519|Homo sapiens fatty acid omega-hydroxyl...   118   3e-26
L04751-1|AAA58436.1|  519|Homo sapiens cytochrome P450 protein.       117   6e-26
D26481-1|BAA05491.1|  519|Homo sapiens fatty acids omega-hydroxy...   117   6e-26
AY369778-1|AAQ56847.1|  519|Homo sapiens cytochrome P450, family...   117   6e-26
AY280372-1|AAQ21368.1|  519|Homo sapiens cytochrome P450 4A22 pr...   117   6e-26
AL731892-3|CAH72778.1|  519|Homo sapiens cytochrome P450, family...   117   6e-26
S67581-1|AAB29503.1|  591|Homo sapiens fatty acid omega-hydroxyl...   115   2e-25
AY280371-1|AAQ21367.1|  519|Homo sapiens cytochrome P450 4A22K p...   115   2e-25
AF525488-1|AAO16078.1|  519|Homo sapiens cytochrome P450, subfam...   115   2e-25
J04813-1|AAA02993.1|  502|Homo sapiens cytochrome P450 PCN3 prot...   114   3e-25
BC033862-1|AAH33862.1|  502|Homo sapiens cytochrome P450, family...   114   3e-25
AC005020-1|AAS02016.1|  502|Homo sapiens unknown protein.             114   3e-25
AL135960-10|CAI19737.1|  519|Homo sapiens cytochrome P450, famil...   114   4e-25
AF208532-1|AAF76722.1|  519|Homo sapiens fatty acid omega-hydrox...   114   4e-25
AK223008-1|BAD96728.1|  502|Homo sapiens cytochrome P450, family...   113   6e-25
AY358631-1|AAQ88994.1|  505|Homo sapiens EPSW3060 protein.            109   2e-23
AY262056-1|AAO89257.1|  505|Homo sapiens cytochrome P450 protein.     109   2e-23
AL450996-2|CAH71036.1|  505|Homo sapiens cytochrome P450, family...   109   2e-23
AL135960-6|CAI19734.1|  505|Homo sapiens cytochrome P450, family...   109   2e-23
D13705-1|BAA02864.1|  521|Homo sapiens fatty acid omega-hydroxyl...   106   9e-23
M18907-1|AAA35745.1|  503|Homo sapiens protein ( Human P450 mRNA...   102   2e-21
DQ924960-1|ABI96208.1|  503|Homo sapiens cytochrome P450 family ...   102   2e-21
DQ005611-1|AAY16980.1|  503|Homo sapiens cytochrome P450, family...   102   2e-21
BC101631-1|AAI01632.1|  503|Homo sapiens cytochrome P450, subfam...   102   2e-21
BC069418-1|AAH69418.1|  503|Homo sapiens cytochrome P450, family...   102   2e-21
AJ563377-1|CAD91345.1|  353|Homo sapiens cytochrome P450 protein.     102   2e-21
AJ563376-2|CAD91645.1|  430|Homo sapiens cytochrome P450 protein.     102   2e-21
AJ563375-1|CAD91343.1|  503|Homo sapiens cytochrome P450 protein.     102   2e-21
AF280107-2|AAG32290.1|  503|Homo sapiens cytochrome P450 polypep...   102   2e-21
AF209389-1|AAF21034.1|  503|Homo sapiens cytochrome P450 IIIA4 p...   102   2e-21
X12387-1|CAA30944.1|  503|Homo sapiens protein ( Human mRNA for ...   101   2e-21
M13785-1|AAA35742.1|  504|Homo sapiens protein ( Human liver glu...   101   2e-21
D00003-1|BAA00001.1|  504|Homo sapiens cytochrome P-450 protein.      101   2e-21
M14096-1|AAA35744.1|  503|Homo sapiens protein ( Human cytochrom...   101   4e-21
J04449-1|AAA35747.1|  502|Homo sapiens cytochrome P450 nifedipin...   101   4e-21
AF182273-1|AAF13598.1|  503|Homo sapiens cytochrome P450-3A4 pro...   100   7e-21
D00408-1|BAA00310.1|  503|Homo sapiens cytochrome P-450 HFLa pro...    99   2e-20
BC067436-1|AAH67436.1|  503|Homo sapiens cytochrome P450, family...    99   2e-20
AF315325-1|AAG48618.1|  535|Homo sapiens cytochrome P450 variant...    99   2e-20
AF280107-3|AAG32289.1|  503|Homo sapiens cytochrome P450 polypep...    99   2e-20
L13286-1|AAA62379.1|  513|Homo sapiens 1,25-dihydroxyvitamin D3 ...    96   1e-19
BC022539-1|AAH22539.1|  500|Homo sapiens cytochrome P450, family...    95   3e-19
AF094480-1|AAD41244.1|  500|Homo sapiens cholesterol 24-hydroxyl...    95   3e-19
X59812-1|CAA42481.1|  530|Homo sapiens Vitamin D3 25-hydroxylase...    95   4e-19
M62401-1|AAA52142.1|  531|Homo sapiens sterol 27-hydroxylase pro...    95   4e-19
BC051851-1|AAH51851.1|  531|Homo sapiens cytochrome P450, family...    95   4e-19
BC040430-1|AAH40430.1|  531|Homo sapiens cytochrome P450, family...    95   4e-19
Y07508-1|CAA68807.1|  503|Homo sapiens protein ( Human mRNA for ...    94   5e-19
X13589-1|CAA31929.1|  503|Homo sapiens protein ( Human mRNA for ...    94   5e-19
M30804-1|AAA35728.1|  503|Homo sapiens protein ( Human aromatase...    94   5e-19
M22246-1|AAA35557.1|  503|Homo sapiens protein ( Human aromatase...    94   5e-19
M18856-1|AAA35556.1|  419|Homo sapiens protein ( Human aromatase...    94   5e-19
DQ118405-1|AAZ23558.1|  503|Homo sapiens cytochrome P450 subfami...    94   5e-19
BC107785-1|AAI07786.1|  503|Homo sapiens cytochrome P450, family...    94   5e-19
BC035959-1|AAH35959.1|  503|Homo sapiens cytochrome P450, family...    94   5e-19
AY957953-1|AAX44046.1|  503|Homo sapiens cytochrome P450, family...    94   5e-19
AY288916-1|AAP31972.1|  508|Homo sapiens cytochrome P450, family...    94   5e-19
AF256213-1|AAG00416.1|  508|Homo sapiens 25- hydroxyvitamin D-1-...    94   5e-19
AF246895-1|AAF64299.1|  508|Homo sapiens 25-hydroxyvitamin D-1-a...    94   5e-19
AF027152-1|AAC51854.1|  508|Homo sapiens P450 25-hydroxyvitamin ...    94   5e-19
AF020192-1|AAC51853.1|  508|Homo sapiens 25-hydroxyvitamin D-1-a...    94   5e-19
AB006987-1|BAA23418.1|  508|Homo sapiens 25-hydroxyvitamin D3 1-...    94   5e-19
AB005990-1|BAA22657.1|  508|Homo sapiens 25-hydroxyvitamin D3 1a...    94   5e-19
AB005989-1|BAA22656.1|  508|Homo sapiens 25-hydroxyvitamin D3 1a...    94   5e-19
AB005038-1|BAA23416.1|  508|Homo sapiens 25-hydroxyvitamin D3 1-...    94   5e-19
AY178622-1|AAO21126.1|  531|Homo sapiens steroid hydroxylase pro...    94   6e-19
AY858838-1|AAW50795.1|  372|Homo sapiens vitamin D 24-hydroxylas...    93   9e-19
AL138805-3|CAB91829.1|  514|Homo sapiens cytochrome P450, family...    93   9e-19
AL138805-1|CAM27342.1|  372|Homo sapiens cytochrome P450, family...    93   9e-19
AK131190-1|BAD18388.1|  372|Homo sapiens .-.-).  protein.              93   9e-19
M28420-1|AAA52141.1|  419|Homo sapiens cytochrome P-450 aromatas...    93   1e-18
J04127-1|AAA52132.1|  503|Homo sapiens CYP19 protein.                  93   1e-18
S67623-1|AAB29308.1|  257|Homo sapiens 25-hydroxyvitamin D 24-hy...    93   1e-18
BC039307-1|AAH39307.1|  372|Homo sapiens FLJ16008 protein protein.     93   1e-18
M63871-1|AAA59984.1|  508|Homo sapiens CYP17 protein.                  92   2e-18
M31153-1|AAA52140.1|  508|Homo sapiens CYP17 protein.                  92   2e-18
M19489-1|AAA36405.1|  508|Homo sapiens CYP17 protein.                  92   2e-18
M14564-1|AAA52151.1|  508|Homo sapiens CYP17 protein.                  92   2e-18
DQ530598-1|ABF50972.1|  508|Homo sapiens cytochrome P450, family...    92   2e-18
BT020000-1|AAV38803.1|  508|Homo sapiens cytochrome P450, family...    92   2e-18
BC063388-1|AAH63388.1|  508|Homo sapiens cytochrome P450, family...    92   2e-18
BC062997-1|AAH62997.1|  508|Homo sapiens cytochrome P450, family...    92   2e-18
AY390424-1|AAQ92352.1|  503|Homo sapiens cytochrome P450 CYP3A43...    92   2e-18
AL358790-3|CAI52498.1|  508|Homo sapiens cytochrome P450, family...    92   2e-18
BC100981-1|AAI00982.1|  393|Homo sapiens CYP3A43 protein protein.      91   3e-18
BC041158-1|AAH41158.1|  455|Homo sapiens CYP4A11 protein protein.      91   3e-18
AY390425-1|AAQ92353.1|  503|Homo sapiens cytochrome P450 CYP3A43...    91   3e-18
AL731892-4|CAH72779.1|  455|Homo sapiens cytochrome P450, family...    91   3e-18
AF337813-1|AAK38841.1|  503|Homo sapiens cytochrome P450 subfami...    91   3e-18
AF319634-1|AAK00325.1|  503|Homo sapiens cytochrome P450 CYP3A43...    91   3e-18
AF280108-1|AAG33009.1|  503|Homo sapiens cytochrome P450 subfami...    91   3e-18
AC011904-4|AAS07395.1|  503|Homo sapiens unknown protein.              91   3e-18
BC104909-1|AAI04910.1|  501|Homo sapiens cytochrome P450, family...    91   6e-18
BC104907-1|AAI04908.1|  501|Homo sapiens cytochrome P450, family...    91   6e-18
AY323817-1|AAQ23114.1|  501|Homo sapiens cytochrome P450 2R1 pro...    91   6e-18
BC025761-1|AAH25761.2|  490|Homo sapiens cytochrome P450, family...    89   1e-17
AL135960-11|CAI19738.1|  455|Homo sapiens cytochrome P450, famil...    89   2e-17
AF280109-1|AAG33010.1|  504|Homo sapiens cytochrome P450 subfami...    88   3e-17
AC011904-5|AAS07394.1|  504|Homo sapiens unknown protein.              88   3e-17
X65962-1|CAA46778.1|  356|Homo sapiens cytochrome P-450 II C pro...    87   7e-17
M61858-1|AAA52145.1|  370|Homo sapiens CYP2C17 protein.                87   1e-16
M61854-1|AAB59426.1|  490|Homo sapiens cytochrome protein.             86   2e-16
L39102-1|AAL31348.1|  217|Homo sapiens S-mephenytoin 4-hydroxyla...    86   2e-16
X13930-1|CAA32118.1|  494|Homo sapiens protein ( Human CYP2A4 mR...    85   2e-16
X13929-1|CAA32117.1|  448|Homo sapiens P-450 IIA3 protein (1 is ...    85   2e-16
M33318-1|AAA52067.1|  494|Homo sapiens CYP2A protein.                  85   2e-16
L07093-1|AAA36660.1|  468|Homo sapiens cytochrome P450 protein.        85   2e-16
BC096256-1|AAH96256.1|  494|Homo sapiens cytochrome P450, family...    85   2e-16
BC096255-1|AAH96255.1|  494|Homo sapiens cytochrome P450, family...    85   2e-16
BC096254-1|AAH96254.1|  494|Homo sapiens cytochrome P450, family...    85   2e-16
BC096253-1|AAH96253.3|  494|Homo sapiens cytochrome P450, family...    85   2e-16
AY796203-1|AAV41877.1|  490|Homo sapiens cytochrome P450, family...    85   2e-16
AL583836-2|CAH74068.1|  490|Homo sapiens cytochrome P450, family...    85   2e-16
AL133513-2|CAH73444.1|  490|Homo sapiens cytochrome P450, family...    85   2e-16
AK090886-1|BAC03539.1|  337|Homo sapiens protein ( Homo sapiens ...    85   2e-16
AF182275-1|AAF13600.1|  494|Homo sapiens cytochrome P450-2A6 pro...    85   2e-16
M33317-1|AAA52138.1|  494|Homo sapiens CYP2A protein.                  85   3e-16
BC117165-1|AAI17166.1|  494|Homo sapiens cytochrome P450, family...    85   3e-16
X13897-1|CAA32097.1|  489|Homo sapiens protein ( Human mRNA for ...    84   7e-16
S46963-1|AAB23864.2|  477|Homo sapiens cytochrome P-450 protein.       83   9e-16
M21940-1|AAA52159.1|  383|Homo sapiens CYP2C protein.                  83   9e-16
D00173-1|BAA00123.1|  487|Homo sapiens cytochrome P-450 protein.       83   9e-16
BC125054-1|AAI25055.1|  490|Homo sapiens cytochrome P450, family...    83   9e-16
AY702706-1|AAT94065.1|  490|Homo sapiens cytochrome P450, family...    83   9e-16
AY341248-1|AAP88931.1|  490|Homo sapiens cytochrome P450, family...    83   9e-16
AL359672-1|CAH71303.1|  490|Homo sapiens cytochrome P450, family...    83   9e-16
M33388-1|AAA53500.1|  497|Homo sapiens cytochrome P450 IID6 prot...    83   1e-15
M33189-1|AAA35737.1|  500|Homo sapiens protein ( Human debrisoqu...    83   1e-15
M24499-1|AAA36403.1|  373|Homo sapiens cytochrome P450db1 protein.     83   1e-15
DQ282154-1|ABB77902.1|  497|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
DQ282152-1|ABB77900.1|  497|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
DQ282151-1|ABB77899.1|  496|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
DQ282146-1|ABB77897.1|  497|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
DQ282145-1|ABB77896.1|  497|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
DQ282144-1|ABB77895.1|  497|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
DQ211354-2|ABB01372.1|  497|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
DQ211353-2|ABB01371.1|  497|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
DQ211353-1|ABB01370.1|  497|Homo sapiens cytochrome P450 2D6 pro...    83   1e-15
BC132767-1|AAI32768.1|  544|Homo sapiens cytochrome P450, family...    83   1e-15
BC075024-1|AAH75024.1|  497|Homo sapiens cytochrome P450, family...    83   1e-15
BC075023-1|AAH75023.1|  497|Homo sapiens cytochrome P450, family...    83   1e-15
AY545216-1|AAS55001.1|  497|Homo sapiens cytochrome P4502D6 prot...    83   1e-15
AY343323-1|AAQ21380.1|  544|Homo sapiens cytochrome P450 protein.      83   1e-15
AB209492-1|BAD92729.1|  566|Homo sapiens Debrisoquine 4-hydroxyl...    83   1e-15
U37143-1|AAC50370.2|  502|Homo sapiens cytochrome P450 monooxyge...    83   2e-15
U22029-1|AAB40520.1|  494|Homo sapiens cytochrome P450 protein.        83   2e-15
M21939-1|AAA52158.1|  485|Homo sapiens CYP2C protein.                  83   2e-15
M15331-1|AAA52157.1|  485|Homo sapiens CYP2C protein.                  83   2e-15
BC032594-1|AAH32594.1|  502|Homo sapiens cytochrome P450, family...    83   2e-15
AY426985-1|AAQ93356.1|  502|Homo sapiens cytochrome P450, family...    83   2e-15
AF272142-1|AAM44456.1|  502|Homo sapiens cytochrome P450 protein.      83   2e-15
X08006-1|CAA30807.1|  497|Homo sapiens cytochrome P450 db1 protein.    82   2e-15
M20403-1|AAA52153.1|  497|Homo sapiens CYP2D protein.                  82   2e-15
AY513608-1|AAR90939.1|  494|Homo sapiens cytochrome P450 2A13 va...    82   2e-15
AY513606-1|AAR90937.1|  494|Homo sapiens cytochrome P450 2A13 va...    82   2e-15
AY513605-1|AAR90936.1|  494|Homo sapiens cytochrome P450 2A13 va...    82   2e-15
AY513604-1|AAR90935.1|  494|Homo sapiens cytochrome P450 2A13 va...    82   2e-15
AF209774-1|AAG35775.1|  494|Homo sapiens cytochrome P450 2A13 pr...    82   2e-15
AB080265-1|BAB85489.1|  502|Homo sapiens cytochrome P450 2J2 pro...    82   2e-15
BC100982-1|AAI00983.1|  280|Homo sapiens CYP3A43 protein protein.      81   4e-15
U22027-1|AAB40518.1|  494|Homo sapiens cytochrome P450 protein.        81   5e-15
AY513609-1|AAR90940.1|  494|Homo sapiens cytochrome P450 2A13 va...    81   5e-15
AJ563378-3|CAD91347.1|  173|Homo sapiens hypothetical protein pr...    81   5e-15
AJ563378-2|CAD91647.1|  160|Homo sapiens cytochrome P450 protein.      81   5e-15
D12621-1|BAA02145.1|  389|Homo sapiens cytochrome P-450LTBV prot...    81   6e-15
BC106758-1|AAI06759.1|  497|Homo sapiens cytochrome P450, family...    81   6e-15
DQ282162-1|ABB77909.1|  500|Homo sapiens cytochrome P450 2D6 pro...    80   1e-14
DQ282160-1|ABB77908.1|  497|Homo sapiens cytochrome P450 2D6 pro...    80   1e-14
DQ282159-1|ABB77907.1|  497|Homo sapiens cytochrome P450 2D6 pro...    80   1e-14
DQ282158-1|ABB77906.1|  497|Homo sapiens cytochrome P450 2D6 pro...    80   1e-14
DQ282157-1|ABB77905.1|  497|Homo sapiens cytochrome P450 2D6 pro...    80   1e-14
DQ282156-1|ABB77904.1|  497|Homo sapiens cytochrome P450 2D6 pro...    80   1e-14
DQ282155-1|ABB77903.1|  497|Homo sapiens cytochrome P450 2D6 pro...    80   1e-14
DQ282147-1|ABB77898.1|  497|Homo sapiens cytochrome P450 2D6 pro...    80   1e-14
CR456430-1|CAG30316.1|  446|Homo sapiens CYP2D6 protein.               80   1e-14
BC126858-1|AAI26859.1|  497|Homo sapiens cytochrome P450, family...    80   1e-14
BC106757-1|AAI06758.1|  446|Homo sapiens cytochrome P450, family...    80   1e-14
BC067432-1|AAH67432.1|  497|Homo sapiens cytochrome P450, family...    80   1e-14
BC066877-1|AAH66877.1|  446|Homo sapiens CYP2D6 protein protein.       80   1e-14
BC067433-1|AAH67433.1|  493|Homo sapiens cytochrome P450, family...    79   1e-14
DQ282153-1|ABB77901.1|  497|Homo sapiens cytochrome P450 2D6 pro...    79   3e-14
BC033691-1|AAH33691.1|  504|Homo sapiens cytochrome P450, family...    79   3e-14
AY358603-1|AAQ88966.1|  504|Homo sapiens Cytochrome p450 protein.      79   3e-14
AK027605-1|BAB55227.1|  564|Homo sapiens protein ( Homo sapiens ...    79   3e-14
AF335278-1|AAK13498.1|  504|Homo sapiens cytochrome P450 2S1 pro...    79   3e-14
AF280110-1|AAG33011.1|  420|Homo sapiens cytochrome P450 subfami...    79   3e-14
U22028-1|AAB40519.1|  494|Homo sapiens cytochrome P450 protein.        78   3e-14
K03192-1|AAA52147.1|  331|Homo sapiens CYP1A1 protein.                 78   3e-14
J02843-1|AAA52155.1|  493|Homo sapiens protein ( Human cytochrom...    78   3e-14
J02625-1|AAA35743.1|  493|Homo sapiens protein ( Human cytochrom...    78   3e-14
DQ515958-1|ABF47105.1|  493|Homo sapiens cytochrome P450, family...    78   3e-14
DQ149222-1|AAZ77710.1|  493|Homo sapiens cytochrome P450 2E1 pro...    78   3e-14
AL161645-2|CAH70047.1|  493|Homo sapiens cytochrome P450, family...    78   3e-14
AF233625-1|AAF99279.1|  534|Homo sapiens thromboxane synthase pr...    78   3e-14
AF182276-1|AAF13601.1|  493|Homo sapiens cytochrome P450-2E1 pro...    78   3e-14
AF084225-1|AAD13753.1|  462|Homo sapiens cytochrome P450 2E1 pro...    78   3e-14
AF233624-1|AAF99278.1|  534|Homo sapiens thromboxane synthase pr...    78   5e-14
M80647-1|AAA60618.1|  534|Homo sapiens thromboxane synthase prot...    77   6e-14
D34625-1|BAA07011.1|  533|Homo sapiens thromboxane synthase prot...    77   6e-14
BC067429-1|AAH67429.1|  516|Homo sapiens cytochrome P450, family...    77   6e-14
BC041157-1|AAH41157.1|  534|Homo sapiens thromboxane A synthase ...    77   6e-14
BC014117-1|AAH14117.1|  466|Homo sapiens TBXAS1 protein protein.       77   6e-14
AK223466-1|BAD97186.1|  534|Homo sapiens thromboxane A synthase ...    77   6e-14
AF233622-1|AAF99276.1|  534|Homo sapiens thromboxane synthase pr...    77   6e-14
AF233620-1|AAF99274.1|  534|Homo sapiens thromboxane synthase pr...    77   6e-14
AF233619-1|AAF99273.1|  534|Homo sapiens thromboxane synthase pr...    77   6e-14
AF233618-1|AAF99272.1|  534|Homo sapiens thromboxane synthase pr...    77   6e-14
AF233617-1|AAF99271.1|  534|Homo sapiens thromboxane synthase pr...    77   6e-14
AF233616-1|AAF99270.1|  534|Homo sapiens thromboxane synthase pr...    77   6e-14
AF233615-1|AAF99269.1|  534|Homo sapiens thromboxane synthase pr...    77   6e-14
M61856-1|AAB59356.1|  490|Homo sapiens cytochrome protein.             77   1e-13
BX538127-1|CAD98029.1|  310|Homo sapiens hypothetical protein pr...    77   1e-13
BC096260-1|AAH96260.1|  431|Homo sapiens CYP2C18 protein protein.      77   1e-13
BC096258-1|AAH96258.1|  490|Homo sapiens cytochrome P450, family...    77   1e-13
BC096257-1|AAH96257.1|  490|Homo sapiens cytochrome P450, family...    77   1e-13
BC069666-1|AAH69666.1|  490|Homo sapiens cytochrome P450, family...    77   1e-13
AL583836-1|CAH74067.1|  490|Homo sapiens cytochrome P450, family...    77   1e-13
AK223510-1|BAD97230.1|  490|Homo sapiens cytochrome P450, family...    76   1e-13
AF233623-1|AAF99277.1|  534|Homo sapiens thromboxane synthase pr...    76   1e-13
AF233621-1|AAF99275.1|  534|Homo sapiens thromboxane synthase pr...    76   1e-13
L16876-1|AAA02630.1|  490|Homo sapiens cytochrome P-4502C18 prot...    76   2e-13
BC067435-1|AAH67435.1|  493|Homo sapiens cytochrome P450, family...    76   2e-13
Y00498-1|CAA68550.1|  490|Homo sapiens IIC2 protein.                   75   2e-13
X51535-1|CAA35915.1|  210|Homo sapiens cytochrome P-450 HPH (120...    75   2e-13
M21942-1|AAA52161.1|  462|Homo sapiens CYP2C protein.                  75   2e-13
J02906-1|AAA52156.1|  491|Homo sapiens CYP2F1 protein.                 75   2e-13
BC020596-1|AAH20596.1|  490|Homo sapiens cytochrome P450, family...    75   2e-13
AY514490-1|AAR89907.1|  490|Homo sapiens cytochrome P450, family...    75   2e-13
AL359672-5|CAH71307.1|  490|Homo sapiens cytochrome P450, family...    75   2e-13
M21941-1|AAA52160.1|  480|Homo sapiens CYP2C protein.                  75   4e-13
Z00036-1|CAA77335.1|  515|Homo sapiens protein ( Human mRNA for ...    74   6e-13
M55053-1|AAA52146.1|  515|Homo sapiens cytochrome P3-450 protein.      74   6e-13
M31667-1|AAA52163.1|  515|Homo sapiens CYP1A2 protein.                 74   6e-13
M17397-1|AAA35739.1|  490|Homo sapiens protein ( Human cytochrom...    74   6e-13
L00389-1|AAA35738.1|  516|Homo sapiens protein ( Human cytochrom...    74   6e-13
DQ022432-1|AAY26399.1|  516|Homo sapiens cytochrome P450, family...    74   6e-13
BC067428-1|AAH67428.1|  516|Homo sapiens cytochrome P450, family...    74   6e-13
BC067427-1|AAH67427.1|  516|Homo sapiens cytochrome P450, family...    74   6e-13
BC067426-1|AAH67426.1|  516|Homo sapiens cytochrome P450, family...    74   6e-13
BC067425-1|AAH67425.1|  516|Homo sapiens cytochrome P450, family...    74   6e-13
BC067424-1|AAH67424.1|  516|Homo sapiens cytochrome P450, family...    74   6e-13
AF372573-1|AAL69652.1|  495|Homo sapiens cytochrome P450 2F1 pro...    74   6e-13
AF253322-2|AAK25728.1|  516|Homo sapiens cytochrome P450 protein.      74   6e-13
X02612-1|CAA26458.1|  512|Homo sapiens cytochrome P(1)-450 protein.    74   7e-13
AF182274-1|AAF13599.1|  516|Homo sapiens cytochrome P450-1A2 pro...    74   7e-13
X04300-1|CAA27843.1|  512|Homo sapiens P-450 c protein.                73   1e-12
M29874-1|AAA52144.1|  491|Homo sapiens CYP2B protein.                  73   1e-12
M12079-1|AAA52152.1|  191|Homo sapiens POR protein.                    73   1e-12
K03191-1|AAA52139.1|  512|Homo sapiens CYP1A1 protein.                 73   1e-12
EF094025-1|ABK41999.1|  512|Homo sapiens cytochrome P450, family...    73   1e-12
DQ298753-1|ABB84469.1|  491|Homo sapiens cytochrome P450, family...    73   1e-12
BC067431-1|AAH67431.1|  491|Homo sapiens cytochrome P450, family...    73   1e-12
BC067430-1|AAH67430.1|  491|Homo sapiens cytochrome P450, family...    73   1e-12
BC023019-1|AAH23019.1|  512|Homo sapiens cytochrome P450, family...    73   1e-12
AY310359-1|AAQ76692.1|  484|Homo sapiens cytochrome P450 1A1 var...    73   1e-12
AM236047-1|CAJ84704.1|  251|Homo sapiens cytochrome P450 1A1 pro...    73   1e-12
AK223113-1|BAD96833.1|  512|Homo sapiens cytochrome P450, family...    73   1e-12
AF253322-1|AAK25727.1|  512|Homo sapiens cytochrome P450 protein.      73   1e-12
AF182277-1|AAF13602.1|  491|Homo sapiens cytochrome P450-2B6 pro...    73   1e-12
AC023172-1|AAF32444.1|  491|Homo sapiens CYP2B6 protein.               73   1e-12
X05367-1|CAA28965.1|  521|Homo sapiens desmolase protein.              73   2e-12
M28253-1|AAA36404.1|  239|Homo sapiens cytochrome P-450-scc prot...    73   2e-12
M14565-1|AAA52162.1|  521|Homo sapiens CYP11A protein.                 73   2e-12
BC032329-1|AAH32329.1|  521|Homo sapiens cytochrome P450, family...    73   2e-12
M32881-1|AAA35741.1|  503|Homo sapiens protein ( Human steroid 1...    72   2e-12
AK223108-1|BAD96828.1|  512|Homo sapiens cytochrome P450, family...    72   3e-12
AK000366-1|BAA91114.1|  408|Homo sapiens protein ( Homo sapiens ...    71   4e-12
X54741-1|CAA38539.1|  503|Homo sapiens aldosterone  synthase (P-...    70   9e-12
M32879-1|AAA52149.1|  503|Homo sapiens CYP11B1 protein.                70   9e-12
D13752-1|BAA02899.1|  503|Homo sapiens steroid 18-hydroxylase pr...    70   9e-12
BC096287-1|AAH96287.1|  503|Homo sapiens cytochrome P450, family...    70   9e-12
BC096285-1|AAH96285.1|  574|Homo sapiens CYP11B1 protein protein.      70   9e-12
BC093022-1|AAH93022.1|  416|Homo sapiens CYP20A1 protein protein.      70   9e-12
BC033752-1|AAH33752.1|  462|Homo sapiens cytochrome P450, family...    70   9e-12
BC020616-1|AAH20616.1|  462|Homo sapiens cytochrome P450, family...    70   9e-12
AF478474-1|AAL84813.1|  503|Homo sapiens mutated cytochrome P-45...    70   9e-12
U03688-1|AAA19567.1|  543|Homo sapiens cytochrome P450 protein.        70   1e-11
M12078-1|AAA52154.1|  192|Homo sapiens POR protein.                    70   1e-11
BT020001-1|AAV38804.1|  543|Homo sapiens cytochrome P450, family...    70   1e-11
BC012049-1|AAH12049.1|  543|Homo sapiens cytochrome P450, family...    70   1e-11
AL358613-3|CAH72804.1|  428|Homo sapiens cytochrome P450, family...    70   1e-11
AL358613-2|CAH72803.1|  497|Homo sapiens cytochrome P450, family...    70   1e-11
AF005418-1|AAB88881.1|  497|Homo sapiens retinoic acid hydroxyla...    70   1e-11
AC009229-2|AAY15039.1|  543|Homo sapiens unknown protein.              70   1e-11
U56438-1|AAC50809.1|  543|Homo sapiens dioxin-inducible cytochro...    69   2e-11
AY393998-1|AAQ87875.1|  543|Homo sapiens cytochrome P450, family...    69   2e-11
AF450132-1|AAM50512.1|  543|Homo sapiens cytochrome P450 CYP1B1 ...    69   2e-11
X55764-1|CAA39290.1|  503|Homo sapiens protein ( Human mRNA for ...    69   2e-11
BT019979-1|AAV38782.1|  543|Homo sapiens cytochrome P450, family...    69   2e-11
AY359068-1|AAQ89427.1|  462|Homo sapiens P450-like protein protein.    69   3e-11
X58906-1|CAA41709.1|  495|Homo sapiens steroid 21-monooxygenase ...    67   6e-11
X71480-1|CAA50586.1|  141|Homo sapiens cytochrome P450 protein.        67   9e-11
AF183412-1|AAG09681.1|  435|Homo sapiens cytochrome P450 monooxy...    66   2e-10
BC032322-1|AAH32322.1|  509|Homo sapiens cytochrome P450, family...    65   3e-10
AM183949-1|CAJ75803.1|  494|Homo sapiens steroid 21-hydroxylase,...    65   3e-10
U23942-1|AAB39951.1|  509|Homo sapiens lanosterol 14-demethylase...    65   3e-10
M28548-1|AAA52065.1|  495|Homo sapiens protein ( Human mutant 21...    65   3e-10
M26856-1|AAA52064.1|  495|Homo sapiens protein ( Human 21-hydrox...    65   3e-10
M13936-1|AAA59695.1|  494|Homo sapiens CYP21P protein.                 65   3e-10
D55653-1|BAA09512.1|  509|Homo sapiens lanosterol 14-demethylase...    65   3e-10
BX679671-8|CAM26071.1|  464|Homo sapiens cytochrome P450, family...    65   3e-10
BX679671-7|CAM26070.1|  494|Homo sapiens cytochrome P450, family...    65   3e-10
BC125182-1|AAI25183.1|  494|Homo sapiens cytochrome P450, family...    65   3e-10
BC125181-1|AAI25182.1|  495|Homo sapiens cytochrome P450, family...    65   3e-10
AM183951-1|CAJ75805.1|  494|Homo sapiens steroid 21-hydroxylase,...    65   3e-10
AM183950-1|CAJ75804.1|  494|Homo sapiens steroid 21-hydroxylase,...    65   3e-10
AM183947-1|CAJ75801.1|  494|Homo sapiens steroid 21-hydroxylase,...    65   3e-10
AM183946-1|CAJ75800.1|  494|Homo sapiens steroid 21-hydroxylase,...    65   3e-10
AM183945-1|CAJ75799.1|  494|Homo sapiens steroid 21-hydroxylase,...    65   3e-10
AM086565-1|CAJ31104.1|  494|Homo sapiens steroid 21-hydroxylase,...    65   3e-10
AM086564-1|CAJ31103.1|  494|Homo sapiens steroid 21-hydroxylase,...    65   3e-10
AL929593-2|CAI41778.1|  465|Homo sapiens cytochrome P450, family...    65   3e-10
AL929593-1|CAI41779.1|  495|Homo sapiens cytochrome P450, family...    65   3e-10
AL662849-19|CAI17480.1|  465|Homo sapiens cytochrome P450, famil...    65   3e-10
AL662849-18|CAI17479.1|  495|Homo sapiens cytochrome P450, famil...    65   3e-10
AL645922-24|CAI41754.1|  495|Homo sapiens cytochrome P450, famil...    65   3e-10
AL645922-23|CAI41755.1|  465|Homo sapiens cytochrome P450, famil...    65   3e-10
AL049547-7|CAB89301.1|  495|Homo sapiens dJ34F7.3 (cytochrome P4...    65   3e-10
AK054616-1|BAB70774.1|  465|Homo sapiens protein ( Homo sapiens ...    65   3e-10
AF077974-1|AAD45405.1|  403|Homo sapiens cytochrome P450 21-hydr...    65   3e-10
AF019413-2|AAB67982.1|  495|Homo sapiens cytochrome P450 21-hydr...    65   3e-10
AC000120-2|AAB46356.1|  509|Homo sapiens unknown protein.              65   3e-10
U51692-1|AAC50951.1|  503|Homo sapiens lanosterol 14-alpha demet...    64   8e-10
M21550-1|AAA52063.1|  495|Homo sapiens CYP21 protein.                  64   8e-10
AB209700-1|BAD92937.1|  336|Homo sapiens cytochrome P450, family...    64   8e-10
AF237982-1|AAF63329.1|  469|Homo sapiens oxysterol 7alpha-hydrox...    63   1e-09
AM183948-1|CAJ75802.1|  494|Homo sapiens steroid 21-hydroxylase ...    63   1e-09
AL135960-9|CAI19736.1|  421|Homo sapiens cytochrome P450, family...    63   1e-09
AL591242-1|CAH73899.1|  469|Homo sapiens cytochrome P450, family...    62   2e-09
AL035670-1|CAI20276.1|  469|Homo sapiens cytochrome P450, family...    62   2e-09
M12792-1|AAB59440.1|  494|Homo sapiens steroid 21-hydroxylase pr...    62   2e-09
L16883-1|AAD13467.1|  169|Homo sapiens cytochrome P-450 2C protein.    62   3e-09
BC010358-1|AAH10358.1|  469|Homo sapiens cytochrome P450, family...    62   3e-09
AY220845-1|AAO49806.1|  516|Homo sapiens cytochrome P450 protein.      62   3e-09
AM233517-1|CAJ80720.1|  175|Homo sapiens cytochrome P450 1A1 pro...    62   3e-09
M24667-1|AAA52148.1|  256|Homo sapiens steroid 11-beta-hydroxyla...    60   7e-09
BC096259-1|AAH96259.1|  443|Homo sapiens CYP2C18 protein protein.      60   1e-08
M17252-1|AAA59985.1|  230|Homo sapiens CYP21 protein.                  60   1e-08
AF040259-1|AAD10199.1|  144|Homo sapiens cytochrome P450 1A1 pro...    55   4e-07
BC109084-1|AAI09085.1|  448|Homo sapiens CYP24A1 protein protein.      54   5e-07
BC109083-1|AAI09084.1|  448|Homo sapiens CYP24A1 protein protein.      54   5e-07
AL138805-2|CAM27343.1|  448|Homo sapiens cytochrome P450, family...    54   5e-07
AC011737-1|AAX88915.1|  382|Homo sapiens unknown protein.              54   5e-07
DQ016495-1|AAY34975.1|  195|Homo sapiens cytochrome P450 1B1 pro...    54   8e-07
BC109205-1|AAI09206.1|  512|Homo sapiens cytochrome P450, family...    52   3e-06
BC069443-1|AAH69443.1|  512|Homo sapiens cytochrome P450, family...    52   3e-06
AF252297-1|AAF76003.1|  512|Homo sapiens cytochrome P450 retinoi...    52   3e-06
AC007002-1|AAY14690.1|  512|Homo sapiens unknown protein.              52   3e-06
M80646-1|AAA60617.1|  460|Homo sapiens thromboxane synthase prot...    51   6e-06
AM233518-1|CAJ80721.1|  157|Homo sapiens cytochrome P450 1A1 pro...    50   8e-06
M17398-1|AAA35740.1|  393|Homo sapiens protein ( Human cytochrom...    50   1e-05
M29873-1|AAA52143.1|  377|Homo sapiens CYP2B protein.                  50   1e-05
BC041174-1|AAH41174.1|  377|Homo sapiens CYP2B7P1 protein protein.     50   1e-05
BC056258-1|AAH56258.1|  359|Homo sapiens CYP19A1 protein protein.      48   6e-05
BC020767-1|AAH20767.1|  360|Homo sapiens Unknown (protein for IM...    48   6e-05
S77409-1|AAB34643.1|  228|Homo sapiens steroid 18-hydroxylase pr...    46   2e-04
AK097373-1|BAC05026.1|  340|Homo sapiens protein ( Homo sapiens ...    46   2e-04
L36085-1|AAC01761.1|  441|Homo sapiens thromboxane A2 synthase p...    44   7e-04
DQ680079-1|ABG25922.1|  347|Homo sapiens truncated cytochrome P4...    44   7e-04
BC096286-1|AAH96286.1|  437|Homo sapiens cytochrome P450, family...    44   0.001
AK127151-1|BAC86855.1|  146|Homo sapiens protein ( Homo sapiens ...    42   0.002
AF144566-1|AAD30164.1|  339|Homo sapiens cytochrome P450 epoxyge...    42   0.002
AY871801-1|AAX62803.1|  483|Homo sapiens cytochrome P450 family ...    42   0.003
AK094090-1|BAC04283.1|  153|Homo sapiens protein ( Homo sapiens ...    42   0.003
AJ877238-1|CAI47002.1|   97|Homo sapiens putative cytochrome P45...    40   0.015
AL358613-1|CAH72802.2|  522|Homo sapiens cytochrome P450, family...    39   0.020
AJ563379-2|CAD91649.1|   84|Homo sapiens cytochrome P450 protein.      39   0.020
AY356349-1|AAQ55485.1|  522|Homo sapiens cytochrome P450 protein.      39   0.026
AC005336-2|AAC27731.1|   93|Homo sapiens F20191_1, partial CDS p...    38   0.034
BC041839-1|AAH41839.1|   51|Homo sapiens CYP4V2 protein protein.       36   0.24 
BC128535-1|AAI28536.1|  143|Homo sapiens LOC283480 protein protein.    34   0.56 
AY064484-1|AAL57719.1|  295|Homo sapiens truncated cytochrome P4...    33   1.3  
AF176805-1|AAK11850.1|  506|Homo sapiens oxysterol 7alpha-hydrox...    31   3.9  
AF127090-1|AAD20021.1|  506|Homo sapiens oxysterol 7alpha-hydrox...    31   3.9  
AC004914-2|AAP21887.1|  311|Homo sapiens unknown protein.              31   5.2  
AC004914-1|AAD21788.1|  348|Homo sapiens unknown protein.              31   5.2  
AY691428-1|AAV80764.1|  360|Homo sapiens WIPI-4 protein.               30   9.0  

>BC060857-1|AAH60857.1|  525|Homo sapiens cytochrome P450, family 4,
           subfamily V, polypeptide 2 protein.
          Length = 525

 Score =  174 bits (423), Expect = 4e-43
 Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 18/324 (5%)

Query: 6   ETALGIKMEDHSAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVL 65
           ETA+G  +   S  + +Y +A++ +  ++  R +  WL  D  Y   K      + +K+L
Sbjct: 202 ETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKIL 261

Query: 66  HNMSNTALQQRKSVFLQEHDAASD----KPT--------DIILETC---GGAFSDKDVRE 110
           H  +N+ + +R +      D   D     P+        D++L      G   S +D+RE
Sbjct: 262 HTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIRE 321

Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
           EVD  +F GHDT +  +  +L LLGS+P+VQ KV +E+  V G ++R  T ED  +L YL
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           E V+KE++R++P  P+ AR    + ++  Y    G+  +++ + +H+   +  + ++F+P
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQP 441

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           ER+  E A    P  +  FS G R+CIG+ +A+M  KT LS +LR + + S+    E  L
Sbjct: 442 ERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 501

Query: 290 EA--ILRPHRGHYIAIERRSKDDK 311
           E   ILRP  G +I ++RR+ D++
Sbjct: 502 EGQLILRPSNGIWIKLKRRNADER 525


>AY422002-1|AAR31180.1|  525|Homo sapiens cytochrome P450 4V2
           protein.
          Length = 525

 Score =  174 bits (423), Expect = 4e-43
 Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 18/324 (5%)

Query: 6   ETALGIKMEDHSAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVL 65
           ETA+G  +   S  + +Y +A++ +  ++  R +  WL  D  Y   K      + +K+L
Sbjct: 202 ETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKIL 261

Query: 66  HNMSNTALQQRKSVFLQEHDAASD----KPT--------DIILETC---GGAFSDKDVRE 110
           H  +N+ + +R +      D   D     P+        D++L      G   S +D+RE
Sbjct: 262 HTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIRE 321

Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
           EVD  +F GHDT +  +  +L LLGS+P+VQ KV +E+  V G ++R  T ED  +L YL
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           E V+KE++R++P  P+ AR    + ++  Y    G+  +++ + +H+   +  + ++F+P
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQP 441

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           ER+  E A    P  +  FS G R+CIG+ +A+M  KT LS +LR + + S+    E  L
Sbjct: 442 ERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 501

Query: 290 EA--ILRPHRGHYIAIERRSKDDK 311
           E   ILRP  G +I ++RR+ D++
Sbjct: 502 EGQLILRPSNGIWIKLKRRNADER 525


>AK126473-1|BAC86562.1|  503|Homo sapiens protein ( Homo sapiens
           cDNA FLJ44509 fis, clone UTERU3001585, weakly  similar
           to Cytochrome P450 4c3 (EC 1.14.-.-). ).
          Length = 503

 Score =  174 bits (423), Expect = 4e-43
 Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 18/324 (5%)

Query: 6   ETALGIKMEDHSAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVL 65
           ETA+G  +   S  + +Y +A++ +  ++  R +  WL  D  Y   K      + +K+L
Sbjct: 180 ETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKIL 239

Query: 66  HNMSNTALQQRKSVFLQEHDAASD----KPT--------DIILETC---GGAFSDKDVRE 110
           H  +N+ + +R +      D   D     P+        D++L      G   S +D+RE
Sbjct: 240 HTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIRE 299

Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
           EVD  +F GHDT +  +  +L LLGS+P+VQ KV +E+  V G ++R  T ED  +L YL
Sbjct: 300 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 359

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           E V+KE++R++P  P+ AR    + ++  Y    G+  +++ + +H+   +  + ++F+P
Sbjct: 360 ECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQP 419

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           ER+  E A    P  +  FS G R+CIG+ +A+M  KT LS +LR + + S+    E  L
Sbjct: 420 ERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 479

Query: 290 EA--ILRPHRGHYIAIERRSKDDK 311
           E   ILRP  G +I ++RR+ D++
Sbjct: 480 EGQLILRPSNGIWIKLKRRNADER 503


>AK122600-1|BAC85487.1|  525|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16007 fis, clone KIDNE2006580, weakly  similar
           to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
          Length = 525

 Score =  174 bits (423), Expect = 4e-43
 Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 18/324 (5%)

Query: 6   ETALGIKMEDHSAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVL 65
           ETA+G  +   S  + +Y +A++ +  ++  R +  WL  D  Y   K      + +K+L
Sbjct: 202 ETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKIL 261

Query: 66  HNMSNTALQQRKSVFLQEHDAASD----KPT--------DIILETC---GGAFSDKDVRE 110
           H  +N+ + +R +      D   D     P+        D++L      G   S +D+RE
Sbjct: 262 HTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIRE 321

Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
           EVD  +F GHDT +  +  +L LLGS+P+VQ KV +E+  V G ++R  T ED  +L YL
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           E V+KE++R++P  P+ AR    + ++  Y    G+  +++ + +H+   +  + ++F+P
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQP 441

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           ER+  E A    P  +  FS G R+CIG+ +A+M  KT LS +LR + + S+    E  L
Sbjct: 442 ERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 501

Query: 290 EA--ILRPHRGHYIAIERRSKDDK 311
           E   ILRP  G +I ++RR+ D++
Sbjct: 502 EGQLILRPSNGIWIKLKRRNADER 525


>U02388-1|AAC50052.2|  520|Homo sapiens cytochrome P450 4F2 protein.
          Length = 520

 Score =  144 bits (350), Expect = 3e-34
 Identities = 90/298 (30%), Positives = 158/298 (53%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++++R  +  LH DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++VL+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASVLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D   L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R+   ++ L +    P G   ++ ++G H +     D + + P R+  E      P  F 
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>BC067440-1|AAH67440.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score =  143 bits (346), Expect = 8e-34
 Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++++R  +  LH DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D   L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R+   ++ L +    P G   ++ ++G H +     D + + P R+  E      P  F 
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>AB015306-1|BAA75823.1|  520|Homo sapiens Leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score =  143 bits (346), Expect = 8e-34
 Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++++R  +  LH DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D   L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R+   ++ L +    P G   ++ ++G H +     D + + P R+  E      P  F 
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>D26480-1|BAA05490.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score =  142 bits (344), Expect = 1e-33
 Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++++R  +  LH DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D   L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R+   ++ L +    P G   ++ ++G H +     D + + P R+  E      P  F 
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>BC067439-1|AAH67439.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score =  142 bits (344), Expect = 1e-33
 Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++++R  +  LH DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D   L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R+   ++ L +    P G   ++ ++G H +     D + + P R+  E      P  F 
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>BC067437-1|AAH67437.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score =  142 bits (344), Expect = 1e-33
 Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++++R  +  LH DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D   L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R+   ++ L +    P G   ++ ++G H +     D + + P R+  E      P  F 
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>AF467894-1|AAL67578.1|  520|Homo sapiens cytochrome P450, subfamily
           IVF, polypeptide 2 protein.
          Length = 520

 Score =  142 bits (344), Expect = 1e-33
 Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++++R  +  LH DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D   L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R+   ++ L +    P G   ++ ++G H +     D + + P R+  E      P  F 
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>AC005336-1|AAC27730.1|  520|Homo sapiens CYP4F2 protein.
          Length = 520

 Score =  142 bits (344), Expect = 1e-33
 Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++++R  +  LH DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D   L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R+   ++ L +    P G   ++ ++G H +     D + + P R+  E      P  F 
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>AY792513-1|AAV40834.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 3 protein.
          Length = 520

 Score =  139 bits (336), Expect = 1e-32
 Identities = 87/299 (29%), Positives = 158/299 (52%), Gaps = 17/299 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++T+R Q+  L+ DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D  +L +L   +KES+R++P  P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
           R    ++ L +    P G   ++ ++G H +     D + + P R+ +   + +  P  F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458

Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
             FS G R+CIG+ +AM  MK  L   L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>AF054821-1|AAC08589.1|  520|Homo sapiens cytochrome P-450 protein.
          Length = 520

 Score =  139 bits (336), Expect = 1e-32
 Identities = 87/299 (29%), Positives = 158/299 (52%), Gaps = 17/299 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++T+R Q+  L+ DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D  +L +L   +KES+R++P  P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
           R    ++ L +    P G   ++ ++G H +     D + + P R+ +   + +  P  F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458

Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
             FS G R+CIG+ +AM  MK  L   L R+RV  D T+   K E +LR   G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGIWLRVE 517


>BC028102-1|AAH28102.1|  509|Homo sapiens cytochrome P450, family 4,
           subfamily X, polypeptide 1 protein.
          Length = 509

 Score =  137 bits (332), Expect = 4e-32
 Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)

Query: 17  SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
           ++ +  Y +A+ ++  ++  R      H D ++  +    R  ++ +VL+  ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265

Query: 77  KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
           K   LQ      + P        DI+L   +  G +FSD DV  EV   + AGHDT++  
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324

Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
           ++  L  L  +P+ Q++   EVR +LGD    +T +    + Y    +KE+ R+ P  P 
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383

Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
           I+R     +   +  T PAG   +L +WG+H +     +   F P R+  E +    P  
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443

Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
           +  FS G R+CIG+ +AM+ +K T++ +L  +RV+ D T  L F    IL+P  G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503

Query: 304 ERRSK 308
           ++ S+
Sbjct: 504 KKLSE 508


>AY358537-1|AAQ88901.1|  509|Homo sapiens EFSW1929 protein.
          Length = 509

 Score =  137 bits (332), Expect = 4e-32
 Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)

Query: 17  SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
           ++ +  Y +A+ ++  ++  R      H D ++  +    R  ++ +VL+  ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265

Query: 77  KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
           K   LQ      + P        DI+L   +  G +FSD DV  EV   + AGHDT++  
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324

Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
           ++  L  L  +P+ Q++   EVR +LGD    +T +    + Y    +KE+ R+ P  P 
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383

Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
           I+R     +   +  T PAG   +L +WG+H +     +   F P R+  E +    P  
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443

Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
           +  FS G R+CIG+ +AM+ +K T++ +L  +RV+ D T  L F    IL+P  G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503

Query: 304 ERRSK 308
           ++ S+
Sbjct: 504 KKLSE 508


>AM040940-1|CAJ13826.1|  509|Homo sapiens cytochrome P450 protein.
          Length = 509

 Score =  137 bits (332), Expect = 4e-32
 Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)

Query: 17  SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
           ++ +  Y +A+ ++  ++  R      H D ++  +    R  ++ +VL+  ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265

Query: 77  KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
           K   LQ      + P        DI+L   +  G +FSD DV  EV   + AGHDT++  
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324

Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
           ++  L  L  +P+ Q++   EVR +LGD    +T +    + Y    +KE+ R+ P  P 
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383

Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
           I+R     +   +  T PAG   +L +WG+H +     +   F P R+  E +    P  
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443

Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
           +  FS G R+CIG+ +AM+ +K T++ +L  +RV+ D T  L F    IL+P  G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503

Query: 304 ERRSK 308
           ++ S+
Sbjct: 504 KKLSE 508


>AL450996-1|CAH71035.1|  509|Homo sapiens cytochrome P450, family 4,
           subfamily X, polypeptide 1 protein.
          Length = 509

 Score =  137 bits (332), Expect = 4e-32
 Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)

Query: 17  SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
           ++ +  Y +A+ ++  ++  R      H D ++  +    R  ++ +VL+  ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265

Query: 77  KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
           K   LQ      + P        DI+L   +  G +FSD DV  EV   + AGHDT++  
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324

Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
           ++  L  L  +P+ Q++   EVR +LGD    +T +    + Y    +KE+ R+ P  P 
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383

Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
           I+R     +   +  T PAG   +L +WG+H +     +   F P R+  E +    P  
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443

Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
           +  FS G R+CIG+ +AM+ +K T++ +L  +RV+ D T  L F    IL+P  G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503

Query: 304 ERRSK 308
           ++ S+
Sbjct: 504 KKLSE 508


>AK131355-1|BAD18508.1|  508|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16384 fis, clone TLIVE2007607, weakly  similar
           to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 508

 Score =  137 bits (332), Expect = 4e-32
 Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)

Query: 17  SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
           ++ +  Y +A+ ++  ++  R      H D ++  +    R  ++ +VL+  ++T +Q+R
Sbjct: 205 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 264

Query: 77  KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
           K   LQ      + P        DI+L   +  G +FSD DV  EV   + AGHDT++  
Sbjct: 265 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 323

Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
           ++  L  L  +P+ Q++   EVR +LGD    +T +    + Y    +KE+ R+ P  P 
Sbjct: 324 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 382

Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
           I+R     +   +  T PAG   +L +WG+H +     +   F P R+  E +    P  
Sbjct: 383 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 442

Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
           +  FS G R+CIG+ +AM+ +K T++ +L  +RV+ D T  L F    IL+P  G Y+ +
Sbjct: 443 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 502

Query: 304 ERRSK 308
           ++ S+
Sbjct: 503 KKLSE 507


>AK098065-1|BAC05226.1|  509|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
           CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 509

 Score =  137 bits (332), Expect = 4e-32
 Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)

Query: 17  SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
           ++ +  Y +A+ ++  ++  R      H D ++  +    R  ++ +VL+  ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265

Query: 77  KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
           K   LQ      + P        DI+L   +  G +FSD DV  EV   + AGHDT++  
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324

Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
           ++  L  L  +P+ Q++   EVR +LGD    +T +    + Y    +KE+ R+ P  P 
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383

Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
           I+R     +   +  T PAG   +L +WG+H +     +   F P R+  E +    P  
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443

Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
           +  FS G R+CIG+ +AM+ +K T++ +L  +RV+ D T  L F    IL+P  G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503

Query: 304 ERRSK 308
           ++ S+
Sbjct: 504 KKLSE 508


>AK091806-1|BAC03751.1|  444|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
           CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 444

 Score =  137 bits (332), Expect = 4e-32
 Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)

Query: 17  SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
           ++ +  Y +A+ ++  ++  R      H D ++  +    R  ++ +VL+  ++T +Q+R
Sbjct: 141 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 200

Query: 77  KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
           K   LQ      + P        DI+L   +  G +FSD DV  EV   + AGHDT++  
Sbjct: 201 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 259

Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
           ++  L  L  +P+ Q++   EVR +LGD    +T +    + Y    +KE+ R+ P  P 
Sbjct: 260 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 318

Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
           I+R     +   +  T PAG   +L +WG+H +     +   F P R+  E +    P  
Sbjct: 319 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 378

Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
           +  FS G R+CIG+ +AM+ +K T++ +L  +RV+ D T  L F    IL+P  G Y+ +
Sbjct: 379 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 438

Query: 304 ERRSK 308
           ++ S+
Sbjct: 439 KKLSE 443


>D12620-1|BAA02144.1|  520|Homo sapiens cytochrome P-450LTBV
           protein.
          Length = 520

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/299 (28%), Positives = 157/299 (52%), Gaps = 17/299 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++T+R Q+  L+ DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D  +L +L   +KES+R++P  P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
           R    ++ L +    P G   ++ ++G H +     D + + P R+ +   + +  P  F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458

Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
             FS G R+CIG+ +AM  MK  L   L  +RV  D T+   K E +LR   G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>BC035350-1|AAH35350.1|  524|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 12 protein.
          Length = 524

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y   + ++ A++ +R Q    H DF+Y  +    R  +  +++H+ ++  +++R+    
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279

Query: 82  QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       D A  K  D I       +  G A SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D + +++  +D  +L +L   +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    ++ L +    P G   ++ + GVH +     D + + P R+  E +    P  F 
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+ +L  +R   D T+   KLE I+R   G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517


>AY358977-1|AAQ89336.1|  524|Homo sapiens CYP4F12 protein.
          Length = 524

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y   + ++ A++ +R Q    H DF+Y  +    R  +  +++H+ ++  +++R+    
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279

Query: 82  QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       D A  K  D I       +  G A SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D + +++  +D  +L +L   +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    ++ L +    P G   ++ + GVH +     D + + P R+  E +    P  F 
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+ +L  +R   D T+   KLE I+R   G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517


>AY008841-1|AAG33247.1|  524|Homo sapiens cytochrome P450 isoform
           4F12 protein.
          Length = 524

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y   + ++ A++ +R Q    H DF+Y  +    R  +  +++H+ ++  +++R+    
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279

Query: 82  QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       D A  K  D I       +  G A SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D + +++  +D  +L +L   +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    ++ L +    P G   ++ + GVH +     D + + P R+  E +    P  F 
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+ +L  +R   D T+   KLE I+R   G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517


>AC004523-1|AAC11543.1|  458|Homo sapiens F22329_1 protein.
          Length = 458

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y   + ++ A++ +R Q    H DF+Y  +    R  +  +++H+ ++  +++R+    
Sbjct: 154 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 213

Query: 82  QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       D A  K  D I       +  G A SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 214 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 273

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D + +++  +D  +L +L   +KES+R++P AP I+
Sbjct: 274 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 333

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    ++ L +    P G   ++ + GVH +     D + + P R+  E +    P  F 
Sbjct: 334 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 393

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+ +L  +R   D T+   KLE I+R   G ++ +E
Sbjct: 394 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 451


>AB035131-1|BAB18270.1|  524|Homo sapiens cytochrome P450 protein.
          Length = 524

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y   + ++ A++ +R Q    H DF+Y  +    R  +  +++H+ ++  +++R+    
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279

Query: 82  QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       D A  K  D I       +  G A SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D + +++  +D  +L +L   +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    ++ L +    P G   ++ + GVH +     D + + P R+  E +    P  F 
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+ +L  +R   D T+   KLE I+R   G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517


>AB035130-1|BAB18269.1|  524|Homo sapiens cytochrome P450 protein.
          Length = 524

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y   + ++ A++ +R Q    H DF+Y  +    R  +  +++H+ ++  +++R+    
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279

Query: 82  QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       D A  K  D I       +  G A SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D + +++  +D  +L +L   +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    ++ L +    P G   ++ + GVH +     D + + P R+  E +    P  F 
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+ +L  +R   D T+   KLE I+R   G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517


>AB002461-1|BAA25991.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/299 (28%), Positives = 157/299 (52%), Gaps = 17/299 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++T+R Q+  L+ DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D  +L +L   +KES+R++P  P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
           R    ++ L +    P G   ++ ++G H +     D + + P R+ +   + +  P  F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458

Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
             FS G R+CIG+ +AM  MK  L   L  +RV  D T+   K E +LR   G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>AB002454-1|BAA25990.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score =  136 bits (329), Expect = 9e-32
 Identities = 86/299 (28%), Positives = 157/299 (52%), Gaps = 17/299 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++T+R Q+  L+ DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D  +L +L   +KES+R++P  P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
           R    ++ L +    P G   ++ ++G H +     D + + P R+ +   + +  P  F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458

Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
             FS G R+CIG+ +AM  MK  L   L  +RV  D T+   K E +LR   G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517


>AF133298-1|AAD49566.1|  520|Homo sapiens cytochrome P450 protein.
          Length = 520

 Score =  132 bits (320), Expect = 1e-30
 Identities = 85/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y  A+ ++ A++ +R  +F+ + DF+Y  T    R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLT 279

Query: 82  QEH-----DAASDKPT----DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       A +   T    D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E +++  +D  +L +L   LKES+R++P  P  A
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFA 399

Query: 189 RYSDAEVKL-KNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    +V L  +   P G+   + ++ +H +     D + + P R+  E A    P  F 
Sbjct: 400 RGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L R+R+  D  +     E +LR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVE 517


>BC016853-1|AAH16853.1|  524|Homo sapiens CYP4F11 protein protein.
          Length = 524

 Score =  131 bits (316), Expect = 3e-30
 Identities = 87/298 (29%), Positives = 149/298 (50%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y  A+ ++ A + +R Q+  LH DF+Y  T   +R  +   ++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRRTLP 279

Query: 82  QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       + A  K  D I       +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 TQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAER-DVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E  ++  +D  +L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    +  L +    P G   ++ + G+H +     D + + P R+  E      P  F 
Sbjct: 400 RCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L  +R+    T+   K E ILR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVE 517


>AF236085-1|AAG15889.1|  524|Homo sapiens CYP4F11 protein.
          Length = 524

 Score =  128 bits (310), Expect = 2e-29
 Identities = 86/298 (28%), Positives = 148/298 (49%), Gaps = 15/298 (5%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
           +Y  A+ ++ A + +R Q+  LH DF+Y  T   +R  +   ++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRRTLP 279

Query: 82  QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
            +       + A  K  D I       +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 TQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAER-DVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
            L  L  HP+ Q++   EV+ +L D E  ++  +D  +L +L   +KES+R++P  PVI+
Sbjct: 340 VLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVIS 399

Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
           R    +  L +    P G   ++ + G+H +     D + + P R+  E      P  F 
Sbjct: 400 RCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFI 459

Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
            FS G R+CIG+ +AM  MK  L+  L  +R+     +   K E ILR   G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHIEPRRKPELILRAEGGLWLRVE 517


>X16699-1|CAA34672.1|  511|Homo sapiens protein ( Human mRNA for
           cytochrome P-450HP. ).
          Length = 511

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503


>J02871-1|AAA35712.1|  511|Homo sapiens protein ( Human lung
           cytochrome P450 (IV subfamily) BI protein, complete cds.
           ).
          Length = 511

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503


>DQ518907-1|ABF47106.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503


>BC017758-1|AAH17758.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 209 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 268

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 328

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 387

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 388 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 447

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 448 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 504


>AY151049-1|AAN72312.1|  497|Homo sapiens pulmonary cytochrome P450
           4B1 variant protein.
          Length = 497

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 194 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 253

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 313

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 372

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 373 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 432

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 433 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 489


>AY151048-1|AAN72311.1|  512|Homo sapiens pulmonary cytochrome P450
           4B1 protein.
          Length = 512

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 209 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 268

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 328

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 387

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 388 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 447

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 448 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 504


>AY064485-1|AAL57720.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503


>AL593856-7|CAI16983.1|  497|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 497

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 194 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 253

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 313

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 372

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 373 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 432

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 433 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 489


>AL593856-6|CAI16982.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 209 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 268

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 328

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 387

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 388 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 447

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 448 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 504


>AL593856-5|CAI16981.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503


>AL356793-4|CAI22559.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503


>AL356793-3|CAI22557.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 209 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 268

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 328

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 387

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 388 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 447

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 448 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 504


>AL356793-2|CAI22558.1|  497|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 497

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 194 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 253

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 313

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 372

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 373 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 432

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 433 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 489


>AF491285-1|AAM09532.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score =  121 bits (291), Expect = 4e-27
 Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT ++ ++  
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 328 LYCIALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503


>BC093896-1|AAH93896.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score =  120 bits (290), Expect = 5e-27
 Identities = 80/297 (26%), Positives = 147/297 (49%), Gaps = 15/297 (5%)

Query: 23  YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
           Y  A+ ++ A+   R  +   + DF+Y R+    R  Q   ++H+ +   +Q+R+    Q
Sbjct: 229 YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQ 288

Query: 83  EHDAASDKPT--------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTAL 131
           +   A  K          D++L   +  G   SD+D+R E D  +F GHDT S+ ++  L
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWML 348

Query: 132 SLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
             L  +P+ Q+K   E++ V+   E  ++  +D  +L +    +KES+R YP   +++R 
Sbjct: 349 FNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQ 408

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
              ++KL +    P G   ++ ++G H +     D+  + P R+  +      P  +  F
Sbjct: 409 CTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPF 468

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  ++  ++  L R+R+S D T  +  K E ILR   G ++ +E
Sbjct: 469 SAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525


>BC093894-1|AAH93894.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score =  120 bits (290), Expect = 5e-27
 Identities = 80/297 (26%), Positives = 147/297 (49%), Gaps = 15/297 (5%)

Query: 23  YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
           Y  A+ ++ A+   R  +   + DF+Y R+    R  Q   ++H+ +   +Q+R+    Q
Sbjct: 229 YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQ 288

Query: 83  EHDAASDKPT--------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTAL 131
           +   A  K          D++L   +  G   SD+D+R E D  +F GHDT S+ ++  L
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWML 348

Query: 132 SLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
             L  +P+ Q+K   E++ V+   E  ++  +D  +L +    +KES+R YP   +++R 
Sbjct: 349 FNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQ 408

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
              ++KL +    P G   ++ ++G H +     D+  + P R+  +      P  +  F
Sbjct: 409 CTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPF 468

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  ++  ++  L R+R+S D T  +  K E ILR   G ++ +E
Sbjct: 469 SAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525


>BC069351-1|AAH69351.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score =  120 bits (290), Expect = 5e-27
 Identities = 80/297 (26%), Positives = 147/297 (49%), Gaps = 15/297 (5%)

Query: 23  YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
           Y  A+ ++ A+   R  +   + DF+Y R+    R  Q   ++H+ +   +Q+R+    Q
Sbjct: 229 YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQ 288

Query: 83  EHDAASDKPT--------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTAL 131
           +   A  K          D++L   +  G   SD+D+R E D  +F GHDT S+ ++  L
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWML 348

Query: 132 SLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
             L  +P+ Q+K   E++ V+   E  ++  +D  +L +    +KES+R YP   +++R 
Sbjct: 349 FNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQ 408

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
              ++KL +    P G   ++ ++G H +     D+  + P R+  +      P  +  F
Sbjct: 409 CTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPF 468

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  ++  ++  L R+R+S D T  +  K E ILR   G ++ +E
Sbjct: 469 SAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525


>AY064486-1|AAL57721.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score =  120 bits (288), Expect = 9e-27
 Identities = 84/297 (28%), Positives = 144/297 (48%), Gaps = 13/297 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +  Y  A+ D+  ++ +R   F  H DF+Y  T    R  +  +V H+ ++  +++RK+ 
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267

Query: 80  FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E       ++     L+   GA        SD D+R EVD  +F GHDT +  ++  
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWF 327

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  +  +P+ Q +   EVR +LGD +     +D  ++ YL   +KES R+YP  P + R 
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386

Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
               V  +   + PAGS   + ++ +H++     D + F   R+  E A+   P  F  F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  MK   +  L R+  S D + L  K+ + +LR   G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503


>AK096820-1|BAC04868.1|  531|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39501 fis, clone PROST2016980, moderately
           similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
          Length = 531

 Score =  119 bits (286), Expect = 2e-26
 Identities = 79/297 (26%), Positives = 147/297 (49%), Gaps = 15/297 (5%)

Query: 23  YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
           Y  A+ ++ A+   R  +   + DF+Y R+    R  Q   ++H+ +   +Q+R+    +
Sbjct: 229 YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRR 288

Query: 83  EHDAASDKPT--------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTAL 131
           +   A  K          D++L   +  G   SD+D+R E D  +F GHDT S+ ++  L
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWML 348

Query: 132 SLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
             L  +P+ Q+K   E++ V+   E  ++  +D  +L +    +KES+R YP   +++R 
Sbjct: 349 FNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQ 408

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
              ++KL +    P G   ++ ++G H +     D+  + P R+  +      P  +  F
Sbjct: 409 CTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPF 468

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAIE 304
           S G R+CIG+ +AM  ++  ++  L R+R+S D T  +  K E ILR   G ++ +E
Sbjct: 469 SAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525


>S67580-1|AAB29502.1|  519|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 519

 Score =  118 bits (284), Expect = 3e-26
 Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508


>L04751-1|AAA58436.1|  519|Homo sapiens cytochrome P450 protein.
          Length = 519

 Score =  117 bits (281), Expect = 6e-26
 Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508


>D26481-1|BAA05491.1|  519|Homo sapiens fatty acids
           omega-hydroxylase protein.
          Length = 519

 Score =  117 bits (281), Expect = 6e-26
 Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508


>AY369778-1|AAQ56847.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 519

 Score =  117 bits (281), Expect = 6e-26
 Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508


>AY280372-1|AAQ21368.1|  519|Homo sapiens cytochrome P450 4A22
           protein.
          Length = 519

 Score =  117 bits (281), Expect = 6e-26
 Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+ +++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLSSLVFCRMRNAFHENDAIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
              E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQTEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRLRR 508


>AL731892-3|CAH72778.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 519

 Score =  117 bits (281), Expect = 6e-26
 Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508


>S67581-1|AAB29503.1|  591|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 591

 Score =  115 bits (277), Expect = 2e-25
 Identities = 77/285 (27%), Positives = 138/285 (48%), Gaps = 14/285 (4%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAIL 293
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +  ++
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLV 495


>AY280371-1|AAQ21367.1|  519|Homo sapiens cytochrome P450 4A22K
           protein.
          Length = 519

 Score =  115 bits (277), Expect = 2e-25
 Identities = 80/298 (26%), Positives = 143/298 (47%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T     +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRTPIPMARLVLKSKNGIHLRLRR 508


>AF525488-1|AAO16078.1|  519|Homo sapiens cytochrome P450, subfamily
           IVA, polypeptide 11 protein.
          Length = 519

 Score =  115 bits (277), Expect = 2e-25
 Identities = 79/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R++P  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508


>J04813-1|AAA02993.1|  502|Homo sapiens cytochrome P450 PCN3
           protein.
          Length = 502

 Score =  114 bits (275), Expect = 3e-25
 Identities = 64/208 (30%), Positives = 116/208 (55%), Gaps = 4/208 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  L  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PVA  + R    +V++     P GS  ++  + +H    +
Sbjct: 348 DAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKY 407

Query: 222 GADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS-S 280
             + ++FRPER+ +     DP  +  F TG R+CIG  +A+M+MK  L  +L+ +     
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467

Query: 281 DVTDLEFKL--EAILRPHRGHYIAIERR 306
             T +  KL  + +L+P +   + ++ R
Sbjct: 468 KETQIPLKLDTQGLLQPEKPIVLKVDSR 495


>BC033862-1|AAH33862.1|  502|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 5 protein.
          Length = 502

 Score =  114 bits (275), Expect = 3e-25
 Identities = 64/208 (30%), Positives = 116/208 (55%), Gaps = 4/208 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  L  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PVA  + R    +V++     P GS  ++  + +H    +
Sbjct: 348 DAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKY 407

Query: 222 GADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS-S 280
             + ++FRPER+ +     DP  +  F TG R+CIG  +A+M+MK  L  +L+ +     
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467

Query: 281 DVTDLEFKL--EAILRPHRGHYIAIERR 306
             T +  KL  + +L+P +   + ++ R
Sbjct: 468 KETQIPLKLDTQGLLQPEKPIVLKVDSR 495


>AC005020-1|AAS02016.1|  502|Homo sapiens unknown protein.
          Length = 502

 Score =  114 bits (275), Expect = 3e-25
 Identities = 64/208 (30%), Positives = 116/208 (55%), Gaps = 4/208 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  L  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PVA  + R    +V++     P GS  ++  + +H    +
Sbjct: 348 DAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKY 407

Query: 222 GADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS-S 280
             + ++FRPER+ +     DP  +  F TG R+CIG  +A+M+MK  L  +L+ +     
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467

Query: 281 DVTDLEFKL--EAILRPHRGHYIAIERR 306
             T +  KL  + +L+P +   + ++ R
Sbjct: 468 KETQIPLKLDTQGLLQPEKPIVLKVDSR 495


>AL135960-10|CAI19737.1|  519|Homo sapiens cytochrome P450, family
           4, subfamily A, polypeptide 22 protein.
          Length = 519

 Score =  114 bits (274), Expect = 4e-25
 Identities = 79/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+ +++    +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNLEVFDPSRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRLRR 508


>AF208532-1|AAF76722.1|  519|Homo sapiens fatty acid
           omega-hydroxylase CYP4A11 protein.
          Length = 519

 Score =  114 bits (274), Expect = 4e-25
 Identities = 79/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+ +++    +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNLEVFDPSRFAPGSAQHSHAFLP-F 450

Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           S G R+CIGK +AM  +K   +  L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508


>AK223008-1|BAD96728.1|  502|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 5 variant protein.
          Length = 502

 Score =  113 bits (273), Expect = 6e-25
 Identities = 64/208 (30%), Positives = 116/208 (55%), Gaps = 4/208 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  L  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PVA  + R    +V++     P GS  ++  + +H    +
Sbjct: 348 DAVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKY 407

Query: 222 GADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS-S 280
             + ++FRPER+ +     DP  +  F TG R+CIG  +A+M+MK  L  +L+ +     
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467

Query: 281 DVTDLEFKL--EAILRPHRGHYIAIERR 306
             T +  KL  + +L+P +   + ++ R
Sbjct: 468 KETQIPLKLDTQGLLQPEKPIVLKVDSR 495


>AY358631-1|AAQ88994.1|  505|Homo sapiens EPSW3060 protein.
          Length = 505

 Score =  109 bits (261), Expect = 2e-23
 Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 11/269 (4%)

Query: 23  YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
           Y +A+ ++  +  +R   F  H D V+  +   +   +  + LH  +   +Q RK     
Sbjct: 211 YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKD 270

Query: 83  E--HDAASDKP---TDIILETCGGA---FSDKDVREEVDNIIFAGHDTISTVLTTALSLL 134
           +   D    +     DI+L         FS+ D++ EV   +FAGHDT S+ ++  L  L
Sbjct: 271 KLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCL 330

Query: 135 GSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAE 194
             +P+ Q +  +E+R +LGD    +T E   ++ Y    +KE +R+Y     I+R  D  
Sbjct: 331 AKYPEHQQRCRDEIRELLGDGS-SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKP 389

Query: 195 VKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGFSTGR 252
           +   +  + PAG    + +W +H +  +  D   F P R+  E +    P  F  FS G 
Sbjct: 390 ITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGL 449

Query: 253 RSCIGKVYAMMSMKTTLSFLLRRYRVSSD 281
           R+CIG+ +A++  K  ++  L R++++ D
Sbjct: 450 RNCIGQHFAIIECKVAVALTLLRFKLAPD 478


>AY262056-1|AAO89257.1|  505|Homo sapiens cytochrome P450 protein.
          Length = 505

 Score =  109 bits (261), Expect = 2e-23
 Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 11/269 (4%)

Query: 23  YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
           Y +A+ ++  +  +R   F  H D V+  +   +   +  + LH  +   +Q RK     
Sbjct: 211 YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKD 270

Query: 83  E--HDAASDKP---TDIILETCGGA---FSDKDVREEVDNIIFAGHDTISTVLTTALSLL 134
           +   D    +     DI+L         FS+ D++ EV   +FAGHDT S+ ++  L  L
Sbjct: 271 KLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCL 330

Query: 135 GSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAE 194
             +P+ Q +  +E+R +LGD    +T E   ++ Y    +KE +R+Y     I+R  D  
Sbjct: 331 AKYPEHQQRCRDEIRELLGDGS-SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKP 389

Query: 195 VKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGFSTGR 252
           +   +  + PAG    + +W +H +  +  D   F P R+  E +    P  F  FS G 
Sbjct: 390 ITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGL 449

Query: 253 RSCIGKVYAMMSMKTTLSFLLRRYRVSSD 281
           R+CIG+ +A++  K  ++  L R++++ D
Sbjct: 450 RNCIGQHFAIIECKVAVALTLLRFKLAPD 478


>AL450996-2|CAH71036.1|  505|Homo sapiens cytochrome P450, family 4,
           subfamily Z, polypeptide 1 protein.
          Length = 505

 Score =  109 bits (261), Expect = 2e-23
 Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 11/269 (4%)

Query: 23  YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
           Y +A+ ++  +  +R   F  H D V+  +   +   +  + LH  +   +Q RK     
Sbjct: 211 YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKD 270

Query: 83  E--HDAASDKP---TDIILETCGGA---FSDKDVREEVDNIIFAGHDTISTVLTTALSLL 134
           +   D    +     DI+L         FS+ D++ EV   +FAGHDT S+ ++  L  L
Sbjct: 271 KLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCL 330

Query: 135 GSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAE 194
             +P+ Q +  +E+R +LGD    +T E   ++ Y    +KE +R+Y     I+R  D  
Sbjct: 331 AKYPEHQQRCRDEIRELLGDGS-SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKP 389

Query: 195 VKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGFSTGR 252
           +   +  + PAG    + +W +H +  +  D   F P R+  E +    P  F  FS G 
Sbjct: 390 ITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGL 449

Query: 253 RSCIGKVYAMMSMKTTLSFLLRRYRVSSD 281
           R+CIG+ +A++  K  ++  L R++++ D
Sbjct: 450 RNCIGQHFAIIECKVAVALTLLRFKLAPD 478


>AL135960-6|CAI19734.1|  505|Homo sapiens cytochrome P450, family 4,
           subfamily Z, polypeptide 1 protein.
          Length = 505

 Score =  109 bits (261), Expect = 2e-23
 Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 11/269 (4%)

Query: 23  YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
           Y +A+ ++  +  +R   F  H D V+  +   +   +  + LH  +   +Q RK     
Sbjct: 211 YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKD 270

Query: 83  E--HDAASDKP---TDIILETCGGA---FSDKDVREEVDNIIFAGHDTISTVLTTALSLL 134
           +   D    +     DI+L         FS+ D++ EV   +FAGHDT S+ ++  L  L
Sbjct: 271 KLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCL 330

Query: 135 GSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAE 194
             +P+ Q +  +E+R +LGD    +T E   ++ Y    +KE +R+Y     I+R  D  
Sbjct: 331 AKYPEHQQRCRDEIRELLGDGS-SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKP 389

Query: 195 VKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGFSTGR 252
           +   +  + PAG    + +W +H +  +  D   F P R+  E +    P  F  FS G 
Sbjct: 390 ITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGL 449

Query: 253 RSCIGKVYAMMSMKTTLSFLLRRYRVSSD 281
           R+CIG+ +A++  K  ++  L R++++ D
Sbjct: 450 RNCIGQHFAIIECKVAVALTLLRFKLAPD 478


>D13705-1|BAA02864.1|  521|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 521

 Score =  106 bits (255), Expect = 9e-23
 Identities = 81/300 (27%), Positives = 143/300 (47%), Gaps = 17/300 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNT-ALQQRKS 78
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  +    +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLSHQHTRPKVIQLRKA 273

Query: 79  VFLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
              +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++ 
Sbjct: 274 QLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISW 333

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIAR 189
            L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R
Sbjct: 334 ILYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGR 392

Query: 190 YSDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAG 247
                V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   
Sbjct: 393 ELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP- 450

Query: 248 FSTGRRSCIGKVYAMMSMKTTLSFL-LRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
           FS G R+CIGK +AM  +K     L L R+ +  D T +   +   +L+   G ++ + R
Sbjct: 451 FSGGSRNCIGKQFAMNELKVGQQALTLVRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 510


>M18907-1|AAA35745.1|  503|Homo sapiens protein ( Human P450 mRNA
           encoding nifedipine oxidase, complete cds. ).
          Length = 503

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>DQ924960-1|ABI96208.1|  503|Homo sapiens cytochrome P450 family 3
           subfamily A polypeptide 4 protein.
          Length = 503

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>DQ005611-1|AAY16980.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 4 protein.
          Length = 503

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>BC101631-1|AAI01632.1|  503|Homo sapiens cytochrome P450, subfamily
           IIIA, polypeptide 4 protein.
          Length = 503

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>BC069418-1|AAH69418.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 4 protein.
          Length = 503

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>AJ563377-1|CAD91345.1|  353|Homo sapiens cytochrome P450 protein.
          Length = 353

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 139 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 197

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 198 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 257

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 258 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 317

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 318 CKETQIPLKLSLGGLLQPEKPVVLKVESR 346


>AJ563376-2|CAD91645.1|  430|Homo sapiens cytochrome P450 protein.
          Length = 430

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 216 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 274

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 275 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 334

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 335 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 394

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 395 CKETQIPLKLSLGGLLQPEKPVVLKVESR 423


>AJ563375-1|CAD91343.1|  503|Homo sapiens cytochrome P450 protein.
          Length = 503

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>AF280107-2|AAG32290.1|  503|Homo sapiens cytochrome P450
           polypeptide 4 protein.
          Length = 503

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>AF209389-1|AAF21034.1|  503|Homo sapiens cytochrome P450 IIIA4
           protein.
          Length = 503

 Score =  102 bits (244), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>X12387-1|CAA30944.1|  503|Homo sapiens protein ( Human mRNA for
           cytochrome P-450 (cyp3 locus). ).
          Length = 503

 Score =  101 bits (243), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>M13785-1|AAA35742.1|  504|Homo sapiens protein ( Human liver
           glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
           complete cds. ).
          Length = 504

 Score =  101 bits (243), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 290 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 348

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 349 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 408

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 409 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 468

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 469 CKETQIPLKLSLGGLLQPEKPVVLKVESR 497


>D00003-1|BAA00001.1|  504|Homo sapiens cytochrome P-450 protein.
          Length = 504

 Score =  101 bits (243), Expect = 2e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 290 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 348

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 349 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 408

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 409 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 468

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 469 CKETQIPLKLSLGGLLQPEKPVVLKVESR 497


>M14096-1|AAA35744.1|  503|Homo sapiens protein ( Human cytochrome
           P-450 nifedipine oxidase mRNA, complet cds. ).
          Length = 503

 Score =  101 bits (241), Expect = 4e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>J04449-1|AAA35747.1|  502|Homo sapiens cytochrome P450 nifedipine
           oxidase protein.
          Length = 502

 Score =  101 bits (241), Expect = 4e-21
 Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 288 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 346

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 347 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 406

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 407 WTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 467 CKETQIPLKLSLGGLLQPEKPVVLKVESR 495


>AF182273-1|AAF13598.1|  503|Homo sapiens cytochrome P450-3A4
           protein.
          Length = 503

 Score =  100 bits (239), Expect = 7e-21
 Identities = 60/209 (28%), Positives = 112/209 (53%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG +T S+VL+  +  L +HPDVQ K+  E+  VL + +   T 
Sbjct: 289 ALSDLELVAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L++EYL+ V+ E++R++P+A  + R    +V++     P G   ++  + +H+   +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
             + ++F PER+ +      DP  +  F +G R+CIG  +A+M+MK  L  +L+ +    
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467

Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
                  L+  L  +L+P +   + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496


>D00408-1|BAA00310.1|  503|Homo sapiens cytochrome P-450 HFLa
           protein.
          Length = 503

 Score = 99.1 bits (236), Expect = 2e-20
 Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 2/176 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ KV  E+  VL + +   T 
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L+LEYL+ V+ E++R++PVA  + R    +V++     P G   ++  + +H    +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
             + ++F PER+ +      DP  +  F +G R+CIG  +A+++MK  L  +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463


>BC067436-1|AAH67436.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 7 protein.
          Length = 503

 Score = 99.1 bits (236), Expect = 2e-20
 Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 2/176 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ KV  E+  VL + +   T 
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L+LEYL+ V+ E++R++PVA  + R    +V++     P G   ++  + +H    +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
             + ++F PER+ +      DP  +  F +G R+CIG  +A+++MK  L  +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463


>AF315325-1|AAG48618.1|  535|Homo sapiens cytochrome P450 variant
           3A7 protein.
          Length = 535

 Score = 99.1 bits (236), Expect = 2e-20
 Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 2/176 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ KV  E+  VL + +   T 
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L+LEYL+ V+ E++R++PVA  + R    +V++     P G   ++  + +H    +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
             + ++F PER+ +      DP  +  F +G R+CIG  +A+++MK  L  +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463


>AF280107-3|AAG32289.1|  503|Homo sapiens cytochrome P450
           polypeptide 7 protein.
          Length = 503

 Score = 99.1 bits (236), Expect = 2e-20
 Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 2/176 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +    IFAG++T S+VL+  +  L +HPDVQ KV  E+  VL + +   T 
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  L+LEYL+ V+ E++R++PVA  + R    +V++     P G   ++  + +H    +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
             + ++F PER+ +      DP  +  F +G R+CIG  +A+++MK  L  +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463


>L13286-1|AAA62379.1|  513|Homo sapiens 1,25-dihydroxyvitamin D3
           24-hydroxylase protein.
          Length = 513

 Score = 96.3 bits (229), Expect = 1e-19
 Identities = 64/204 (31%), Positives = 98/204 (48%), Gaps = 2/204 (0%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           S K++   V  +  A  +T +  L   L  L  +P VQ K+  E++ VL + +R   +ED
Sbjct: 311 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRP-REED 369

Query: 164 YLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGA 223
              + YL+A LKESMR+ P  P   R  D    L  Y  P G+  +L    +        
Sbjct: 370 LRNMPYLKACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 429

Query: 224 DADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSDV 282
           D+ QFRPERWL+     +P     F  G+R CIG+  A + +   L +++R+Y + ++D 
Sbjct: 430 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDN 489

Query: 283 TDLEFKLEAILRPHRGHYIAIERR 306
             +E      L P R   IA  +R
Sbjct: 490 EPVEMLHSGTLVPSRELPIAFCQR 513


>BC022539-1|AAH22539.1|  500|Homo sapiens cytochrome P450, family
           46, subfamily A, polypeptide 1 protein.
          Length = 500

 Score = 95.1 bits (226), Expect = 3e-19
 Identities = 65/225 (28%), Positives = 112/225 (49%), Gaps = 4/225 (1%)

Query: 51  RTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEHDAASDKPTDIILETCGGAFSDKDVRE 110
           R +L+E  + I + L  +    +Q+R+    +  +  +D  T I L+   GA  D+ + +
Sbjct: 237 RKQLREVRESI-RFLRQVGRDWVQRRREALKRGEEVPADILTQI-LKAEEGAQDDEGLLD 294

Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
                  AGH+T +  L   +  L   P++  ++  EV  V+G ++R +  ED  RL+YL
Sbjct: 295 NFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDLGRLQYL 353

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
             VLKES+R+YP A    R  + E  +     P  +  +   + + +   +  D   F P
Sbjct: 354 SQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNP 413

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
           +R+   A  P  ++F  FS G RSCIG+ +A M +K  ++ LL+R
Sbjct: 414 DRFGPGAPKPRFTYFP-FSLGHRSCIGQQFAQMEVKVVMAKLLQR 457


>AF094480-1|AAD41244.1|  500|Homo sapiens cholesterol 24-hydroxylase
           protein.
          Length = 500

 Score = 95.1 bits (226), Expect = 3e-19
 Identities = 65/225 (28%), Positives = 112/225 (49%), Gaps = 4/225 (1%)

Query: 51  RTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEHDAASDKPTDIILETCGGAFSDKDVRE 110
           R +L+E  + I + L  +    +Q+R+    +  +  +D  T I L+   GA  D+ + +
Sbjct: 237 RKQLREVRESI-RFLRQVGRDWVQRRREALKRGEEVPADILTQI-LKAEEGAQDDEGLLD 294

Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
                  AGH+T +  L   +  L   P++  ++  EV  V+G ++R +  ED  RL+YL
Sbjct: 295 NFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDLGRLQYL 353

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
             VLKES+R+YP A    R  + E  +     P  +  +   + + +   +  D   F P
Sbjct: 354 SQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNP 413

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
           +R+   A  P  ++F  FS G RSCIG+ +A M +K  ++ LL+R
Sbjct: 414 DRFGPGAPKPRFTYFP-FSLGHRSCIGQQFAQMEVKVVMAKLLQR 457


>X59812-1|CAA42481.1|  530|Homo sapiens Vitamin D3 25-hydroxylase
           protein.
          Length = 530

 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 57/204 (27%), Positives = 109/204 (53%), Gaps = 8/204 (3%)

Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
           G  S ++    +  ++ AG DT S  LT AL  L   P++Q+ ++ EV  V+  A +   
Sbjct: 317 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQ 375

Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            +D+  +  L+AVLKE++R+YPV P  +R  + E+++  +  P  + F+   + V +   
Sbjct: 376 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 435

Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
             ++ + F+P RWL   + AT  +  P     F  G R+C+G+  A + M+  L+ L+++
Sbjct: 436 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 495

Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
           Y+V  + +  +L+     +L P++
Sbjct: 496 YKVVLAPETGELKSVARIVLVPNK 519


>M62401-1|AAA52142.1|  531|Homo sapiens sterol 27-hydroxylase
           protein.
          Length = 531

 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 57/204 (27%), Positives = 109/204 (53%), Gaps = 8/204 (3%)

Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
           G  S ++    +  ++ AG DT S  LT AL  L   P++Q+ ++ EV  V+  A +   
Sbjct: 318 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQ 376

Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            +D+  +  L+AVLKE++R+YPV P  +R  + E+++  +  P  + F+   + V +   
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436

Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
             ++ + F+P RWL   + AT  +  P     F  G R+C+G+  A + M+  L+ L+++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496

Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
           Y+V  + +  +L+     +L P++
Sbjct: 497 YKVVLAPETGELKSVARIVLVPNK 520


>BC051851-1|AAH51851.1|  531|Homo sapiens cytochrome P450, family
           27, subfamily A, polypeptide 1 protein.
          Length = 531

 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 57/204 (27%), Positives = 109/204 (53%), Gaps = 8/204 (3%)

Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
           G  S ++    +  ++ AG DT S  LT AL  L   P++Q+ ++ EV  V+  A +   
Sbjct: 318 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQ 376

Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            +D+  +  L+AVLKE++R+YPV P  +R  + E+++  +  P  + F+   + V +   
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436

Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
             ++ + F+P RWL   + AT  +  P     F  G R+C+G+  A + M+  L+ L+++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496

Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
           Y+V  + +  +L+     +L P++
Sbjct: 497 YKVVLAPETGELKSVARIVLVPNK 520


>BC040430-1|AAH40430.1|  531|Homo sapiens cytochrome P450, family
           27, subfamily A, polypeptide 1 protein.
          Length = 531

 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 57/204 (27%), Positives = 109/204 (53%), Gaps = 8/204 (3%)

Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
           G  S ++    +  ++ AG DT S  LT AL  L   P++Q+ ++ EV  V+  A +   
Sbjct: 318 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQ 376

Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            +D+  +  L+AVLKE++R+YPV P  +R  + E+++  +  P  + F+   + V +   
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436

Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
             ++ + F+P RWL   + AT  +  P     F  G R+C+G+  A + M+  L+ L+++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496

Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
           Y+V  + +  +L+     +L P++
Sbjct: 497 YKVVLAPETGELKSVARIVLVPNK 520


>Y07508-1|CAA68807.1|  503|Homo sapiens protein ( Human mRNA for
           aromatase P-450. ).
          Length = 503

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>X13589-1|CAA31929.1|  503|Homo sapiens protein ( Human mRNA for
           aromatase (estrogen synthetase). ).
          Length = 503

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>M30804-1|AAA35728.1|  503|Homo sapiens protein ( Human aromatase
           cytochrome P-450 gene, exon 10. ).
          Length = 503

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>M22246-1|AAA35557.1|  503|Homo sapiens protein ( Human aromatase
           mRNA, complete cds. ).
          Length = 503

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>M18856-1|AAA35556.1|  419|Homo sapiens protein ( Human aromatase
           (Aro1) mRNA, complete cds. ).
          Length = 419

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 138 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 197

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 198 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 257

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 258 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 315

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 316 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 371

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 372 RRFHVKT 378


>DQ118405-1|AAZ23558.1|  503|Homo sapiens cytochrome P450 subfamily
           19 subfamily A polypeptide 1 protein.
          Length = 503

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>BC107785-1|AAI07786.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>BC035959-1|AAH35959.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>AY957953-1|AAX44046.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + ++R+ +  +E  +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>AY288916-1|AAP31972.1|  508|Homo sapiens cytochrome P450, family
           27, subfamily B, polypeptide 1 protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AF256213-1|AAG00416.1|  508|Homo sapiens 25- hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AF246895-1|AAF64299.1|  508|Homo sapiens 25-hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AF027152-1|AAC51854.1|  508|Homo sapiens P450 25-hydroxyvitamin D-1
           alpha hydroxylase protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AF020192-1|AAC51853.1|  508|Homo sapiens 25-hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AB006987-1|BAA23418.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1-alpha-hydroxylase protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AB005990-1|BAA22657.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1alpha-hydroxylase protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AB005989-1|BAA22656.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1alpha-hydroxylase protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AB005038-1|BAA23416.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1-alpha-hydroxylase protein.
          Length = 508

 Score = 94.3 bits (224), Expect = 5e-19
 Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
           V  ++ AG DT+S  L+ AL  L  HP+VQ  +++E+   L            L +L  L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           +AV+KE +R+YPV P  +R  D ++ + +Y  P  +   L  +   +      + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
            RWL     P P     F  G+RSC+G+  A + ++  L+ +L  + V  +     +  K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490

Query: 289 LEAILRPHR 297
              +L P R
Sbjct: 491 TRTVLVPER 499


>AY178622-1|AAO21126.1|  531|Homo sapiens steroid hydroxylase
           protein.
          Length = 531

 Score = 93.9 bits (223), Expect = 6e-19
 Identities = 57/204 (27%), Positives = 108/204 (52%), Gaps = 8/204 (3%)

Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
           G  S ++    +  ++ AG DT S  LT AL  L   P++Q  ++ EV  V+  A +   
Sbjct: 318 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVV-PAGQVPQ 376

Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            +D+  +  L+AVLKE++R+YPV P  +R  + E+++  +  P  + F+   + V +   
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVSRDPT 436

Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
             ++ + F+P RWL   + AT  +  P     F  G R+C+G+  A + M+  L+ L+++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496

Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
           Y+V  + +  +L+     +L P++
Sbjct: 497 YKVVLAPETGELKSVARIVLVPNK 520


>AY858838-1|AAW50795.1|  372|Homo sapiens vitamin D 24-hydroxylase
           splice variant protein.
          Length = 372

 Score = 93.5 bits (222), Expect = 9e-19
 Identities = 65/205 (31%), Positives = 97/205 (47%), Gaps = 4/205 (1%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK-E 162
           S K++   V  +  A  +T +  L   L  L  +P VQ K+  E++ VL   E  V + E
Sbjct: 170 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL--PENQVPRAE 227

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
           D   + YL+A LKESMR+ P  P   R  D    L  Y  P G+  +L    +       
Sbjct: 228 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 287

Query: 223 ADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSD 281
            D+ QFRPERWL+     +P     F  G+R CIG+  A + +   L +++R+Y + ++D
Sbjct: 288 EDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATD 347

Query: 282 VTDLEFKLEAILRPHRGHYIAIERR 306
              +E      L P R   IA  +R
Sbjct: 348 NEPVEMLHSGTLVPSRELPIAFCQR 372


>AL138805-3|CAB91829.1|  514|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 514

 Score = 93.5 bits (222), Expect = 9e-19
 Identities = 65/205 (31%), Positives = 97/205 (47%), Gaps = 4/205 (1%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK-E 162
           S K++   V  +  A  +T +  L   L  L  +P VQ K+  E++ VL   E  V + E
Sbjct: 312 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL--PENQVPRAE 369

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
           D   + YL+A LKESMR+ P  P   R  D    L  Y  P G+  +L    +       
Sbjct: 370 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 429

Query: 223 ADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSD 281
            D+ QFRPERWL+     +P     F  G+R CIG+  A + +   L +++R+Y + ++D
Sbjct: 430 EDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATD 489

Query: 282 VTDLEFKLEAILRPHRGHYIAIERR 306
              +E      L P R   IA  +R
Sbjct: 490 NEPVEMLHSGTLVPSRELPIAFCQR 514


>AL138805-1|CAM27342.1|  372|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 372

 Score = 93.5 bits (222), Expect = 9e-19
 Identities = 65/205 (31%), Positives = 97/205 (47%), Gaps = 4/205 (1%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK-E 162
           S K++   V  +  A  +T +  L   L  L  +P VQ K+  E++ VL   E  V + E
Sbjct: 170 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL--PENQVPRAE 227

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
           D   + YL+A LKESMR+ P  P   R  D    L  Y  P G+  +L    +       
Sbjct: 228 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 287

Query: 223 ADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSD 281
            D+ QFRPERWL+     +P     F  G+R CIG+  A + +   L +++R+Y + ++D
Sbjct: 288 EDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATD 347

Query: 282 VTDLEFKLEAILRPHRGHYIAIERR 306
              +E      L P R   IA  +R
Sbjct: 348 NEPVEMLHSGTLVPSRELPIAFCQR 372


>AK131190-1|BAD18388.1|  372|Homo sapiens .-.-).  protein.
          Length = 372

 Score = 93.5 bits (222), Expect = 9e-19
 Identities = 62/199 (31%), Positives = 97/199 (48%), Gaps = 7/199 (3%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV-T 160
           A + +++   V  ++ AG DT S  L+  + LL  HP+VQ  VY E+ + LG  ER V T
Sbjct: 164 ALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLG--ERHVPT 221

Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
             D  ++  + A+LKE++R++PV P   R +  ++ +  Y  P G+   L  +       
Sbjct: 222 AADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDE 281

Query: 221 WGADADQFRPERWLEAATLPDPSFFAG--FSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV 278
               A +FRPERWL    L     F    F  G RSCIG+  A + +   +  LL+ + +
Sbjct: 282 NFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEI 341

Query: 279 --SSDVTDLEFKLEAILRP 295
             SS    +  K   +L P
Sbjct: 342 KTSSQTNAVHAKTHGLLTP 360


>M28420-1|AAA52141.1|  419|Homo sapiens cytochrome P-450 aromatase
           protein.
          Length = 419

 Score = 93.1 bits (221), Expect = 1e-18
 Identities = 64/247 (25%), Positives = 122/247 (49%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEH--DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + +++     E   +   D  T+
Sbjct: 138 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECMDFATE 197

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 198 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 257

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 258 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 315

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 316 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 371

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 372 RRFHVKT 378


>J04127-1|AAA52132.1|  503|Homo sapiens CYP19 protein.
          Length = 503

 Score = 93.1 bits (221), Expect = 1e-18
 Identities = 64/247 (25%), Positives = 122/247 (49%), Gaps = 8/247 (3%)

Query: 36  ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEH--DAASDKPTD 93
           + +Q   +  D  +  + L ++ ++ +K L +     + +++     E   +   D  T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECMDFATE 281

Query: 94  IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
           +IL    G  + ++V + +  ++ A  DT+S  L   L L+  HP+V++ +  E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341

Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
             ERD+  +D  +L+ +E  + ESMR  PV  ++ R +  +  +  Y    G+  IL + 
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399

Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
            +H+   +    ++F  E +  A  +P   +F  F  G R C GK  AM+ MK  L  LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455

Query: 274 RRYRVSS 280
           RR+ V +
Sbjct: 456 RRFHVKT 462


>S67623-1|AAB29308.1|  257|Homo sapiens 25-hydroxyvitamin D
           24-hydroxylase cytochrome P450 subunit protein.
          Length = 257

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 62/196 (31%), Positives = 93/196 (47%), Gaps = 4/196 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK-E 162
           S K++   V  +  A  +T +  L   L  L  +P VQ K+  E++ VL   E  V + E
Sbjct: 55  SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL--PENQVPRAE 112

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
           D   + YL+A LKESMR+ P  P   R  D    L  Y  P G+  +L    +       
Sbjct: 113 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 172

Query: 223 ADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSD 281
            D+ QFRPERWL+     +P     F  G+R CIG+  A + +   L +++R+Y + ++D
Sbjct: 173 EDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATD 232

Query: 282 VTDLEFKLEAILRPHR 297
              +E      L P R
Sbjct: 233 NEPVEMLHSGTLVPSR 248


>BC039307-1|AAH39307.1|  372|Homo sapiens FLJ16008 protein protein.
          Length = 372

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 61/199 (30%), Positives = 97/199 (48%), Gaps = 7/199 (3%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV-T 160
           A + +++   V  ++ AG DT S  L+  + +L  HP+VQ  VY E+ + LG  ER V T
Sbjct: 164 ALTLQEIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLG--ERHVPT 221

Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
             D  ++  + A+LKE++R++PV P   R +  ++ +  Y  P G+   L  +       
Sbjct: 222 AADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDE 281

Query: 221 WGADADQFRPERWLEAATLPDPSFFAG--FSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV 278
               A +FRPERWL    L     F    F  G RSCIG+  A + +   +  LL+ + +
Sbjct: 282 NFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEI 341

Query: 279 --SSDVTDLEFKLEAILRP 295
             SS    +  K   +L P
Sbjct: 342 KTSSQTNAVHAKTHGLLTP 360


>M63871-1|AAA59984.1|  508|Homo sapiens CYP17 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>M31153-1|AAA52140.1|  508|Homo sapiens CYP17 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>M19489-1|AAA36405.1|  508|Homo sapiens CYP17 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>M14564-1|AAA52151.1|  508|Homo sapiens CYP17 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>DQ530598-1|ABF50972.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>BT020000-1|AAV38803.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>BC063388-1|AAH63388.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>BC062997-1|AAH62997.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>AY390424-1|AAQ92352.1|  503|Homo sapiens cytochrome P450 CYP3A43.3
           protein.
          Length = 503

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLAN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
             + ++F PER+ +      D   +  F  G R+CIG  +A+ ++K  +   L+ +    
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467

Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
              T +  KL+   IL+P +   + +  R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496


>AL358790-3|CAI52498.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)

Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
           SD  +   + +I  AG +T ++V+   L+ L  +P V+ K+Y E+ + +G   R  T  D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346

Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
             RL  LEA ++E +R+ PVAP +I   ++ +  +  +    G+  I+ LW +H +    
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406

Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
              DQF PER+L  A   L  PS  +  F  G RSCIG++ A   +   +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463


>BC100981-1|AAI00982.1|  393|Homo sapiens CYP3A43 protein protein.
          Length = 393

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 179 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 237

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 238 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 297

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
             + ++F PER+ +      D   +  F  G R+CIG  +A+ ++K  +   L+ +    
Sbjct: 298 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 357

Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
              T +  KL+   IL+P +   + +  R
Sbjct: 358 CKETQIPLKLDNLPILQPEKPIVLKVHLR 386


>BC041158-1|AAH41158.1|  455|Homo sapiens CYP4A11 protein protein.
          Length = 455

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 66/245 (26%), Positives = 117/245 (47%), Gaps = 14/245 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450

Query: 249 STGRR 253
           S G R
Sbjct: 451 SGGSR 455


>AY390425-1|AAQ92353.1|  503|Homo sapiens cytochrome P450 CYP3A43.1
           protein.
          Length = 503

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
             + ++F PER+ +      D   +  F  G R+CIG  +A+ ++K  +   L+ +    
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467

Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
              T +  KL+   IL+P +   + +  R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496


>AL731892-4|CAH72779.1|  455|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 455

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 66/245 (26%), Positives = 117/245 (47%), Gaps = 14/245 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+  ++  R +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450

Query: 249 STGRR 253
           S G R
Sbjct: 451 SGGSR 455


>AF337813-1|AAK38841.1|  503|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 503

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
             + ++F PER+ +      D   +  F  G R+CIG  +A+ ++K  +   L+ +    
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467

Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
              T +  KL+   IL+P +   + +  R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496


>AF319634-1|AAK00325.1|  503|Homo sapiens cytochrome P450 CYP3A43
           protein.
          Length = 503

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
             + ++F PER+ +      D   +  F  G R+CIG  +A+ ++K  +   L+ +    
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467

Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
              T +  KL+   IL+P +   + +  R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496


>AF280108-1|AAG33009.1|  503|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 503

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
             + ++F PER+ +      D   +  F  G R+CIG  +A+ ++K  +   L+ +    
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467

Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
              T +  KL+   IL+P +   + +  R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496


>AC011904-4|AAS07395.1|  503|Homo sapiens unknown protein.
          Length = 503

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
             + ++F PER+ +      D   +  F  G R+CIG  +A+ ++K  +   L+ +    
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467

Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
              T +  KL+   IL+P +   + +  R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496


>BC104909-1|AAI04910.1|  501|Homo sapiens cytochrome P450, family 2,
           subfamily R, polypeptide 1 protein.
          Length = 501

 Score = 90.6 bits (215), Expect = 6e-18
 Identities = 61/209 (29%), Positives = 108/209 (51%), Gaps = 7/209 (3%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           FS +++   V  +I AG +T + VL  A+  +  +P++Q +V  E+  ++G   +  + +
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKP-SWD 353

Query: 163 DYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D  ++ Y EAVL E +R   + P+ I   +  +  ++ Y+ P G+  I  L+ VH    +
Sbjct: 354 DKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKY 413

Query: 222 GADADQFRPERWLEAA-TLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             D + F PER+L+++           FS GRR C+G+  A M M    + LL+R+ +  
Sbjct: 414 WRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473

Query: 281 D---VTDLEFKLEAILRPHRGHYIAIERR 306
               V DL+ +L   L+P + + I  ERR
Sbjct: 474 PHELVPDLKPRLGMTLQP-QPYLICAERR 501


>BC104907-1|AAI04908.1|  501|Homo sapiens cytochrome P450, family 2,
           subfamily R, polypeptide 1 protein.
          Length = 501

 Score = 90.6 bits (215), Expect = 6e-18
 Identities = 61/209 (29%), Positives = 108/209 (51%), Gaps = 7/209 (3%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           FS +++   V  +I AG +T + VL  A+  +  +P++Q +V  E+  ++G   +  + +
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKP-SWD 353

Query: 163 DYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D  ++ Y EAVL E +R   + P+ I   +  +  ++ Y+ P G+  I  L+ VH    +
Sbjct: 354 DKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKY 413

Query: 222 GADADQFRPERWLEAA-TLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             D + F PER+L+++           FS GRR C+G+  A M M    + LL+R+ +  
Sbjct: 414 WRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473

Query: 281 D---VTDLEFKLEAILRPHRGHYIAIERR 306
               V DL+ +L   L+P + + I  ERR
Sbjct: 474 PHELVPDLKPRLGMTLQP-QPYLICAERR 501


>AY323817-1|AAQ23114.1|  501|Homo sapiens cytochrome P450 2R1
           protein.
          Length = 501

 Score = 90.6 bits (215), Expect = 6e-18
 Identities = 61/209 (29%), Positives = 108/209 (51%), Gaps = 7/209 (3%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           FS +++   V  +I AG +T + VL  A+  +  +P++Q +V  E+  ++G   +  + +
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKP-SWD 353

Query: 163 DYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D  ++ Y EAVL E +R   + P+ I   +  +  ++ Y+ P G+  I  L+ VH    +
Sbjct: 354 DKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKY 413

Query: 222 GADADQFRPERWLEAA-TLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             D + F PER+L+++           FS GRR C+G+  A M M    + LL+R+ +  
Sbjct: 414 WRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473

Query: 281 D---VTDLEFKLEAILRPHRGHYIAIERR 306
               V DL+ +L   L+P + + I  ERR
Sbjct: 474 PHELVPDLKPRLGMTLQP-QPYLICAERR 501


>BC025761-1|AAH25761.2|  490|Homo sapiens cytochrome P450, family 2,
           subfamily W, polypeptide 1 protein.
          Length = 490

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 60/179 (33%), Positives = 85/179 (47%), Gaps = 2/179 (1%)

Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
           G F++ +      +++ AG +T S  L  A  L+G HPDVQ +V  E+ RVLG   R   
Sbjct: 279 GLFAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPG-RTPR 337

Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            ED   L Y  AVL E  R   + P + R + A+ +L  +  P G+  I LL  V     
Sbjct: 338 LEDQQALPYTSAVLHEVQRFITLLPHVPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDET 397

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV 278
                 QF P  +L+A         F  FS GRR C+G+  A   +    + LL+RYR+
Sbjct: 398 QWQTPGQFNPGHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQRYRL 456


>AL135960-11|CAI19738.1|  455|Homo sapiens cytochrome P450, family
           4, subfamily A, polypeptide 22 protein.
          Length = 455

 Score = 89.0 bits (211), Expect = 2e-17
 Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 14/245 (5%)

Query: 20  NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
           +Q Y QA+ D+ +++    +  +   D +Y+ T       +  ++ H  ++  +Q RK+ 
Sbjct: 214 SQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273

Query: 80  FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
             +E +    K        DI+L      G   SDKD+R EVD  +F GHDT ++ ++  
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333

Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
           L  L +HP  Q++   E+  +LGD    +T     ++ Y    +KE++R+YP  P I R 
Sbjct: 334 LYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392

Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
               V   +  + P G   +L ++G+H + ++W  + + F P R+   +     +F   F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNLEVFDPSRFAPGSAQHSHAFLP-F 450

Query: 249 STGRR 253
           S G R
Sbjct: 451 SGGSR 455


>AF280109-1|AAG33010.1|  504|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 504

 Score = 88.2 bits (209), Expect = 3e-17
 Identities = 56/210 (26%), Positives = 105/210 (50%), Gaps = 6/210 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPERWLEAATLP--DPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
             + ++F PE           D   +  F  G R+CIG  +A+ ++K  +   L+ +   
Sbjct: 408 WTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 467

Query: 280 -SDVTDLEFKLE--AILRPHRGHYIAIERR 306
               T +  KL+   IL+P +   + +  R
Sbjct: 468 PCKETQIPLKLDNLPILQPEKPIVLKVHLR 497


>AC011904-5|AAS07394.1|  504|Homo sapiens unknown protein.
          Length = 504

 Score = 88.2 bits (209), Expect = 3e-17
 Identities = 56/210 (26%), Positives = 105/210 (50%), Gaps = 6/210 (2%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPERWLEAATLP--DPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
             + ++F PE           D   +  F  G R+CIG  +A+ ++K  +   L+ +   
Sbjct: 408 WTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 467

Query: 280 -SDVTDLEFKLE--AILRPHRGHYIAIERR 306
               T +  KL+   IL+P +   + +  R
Sbjct: 468 PCKETQIPLKLDNLPILQPEKPIVLKVHLR 497


>X65962-1|CAA46778.1|  356|Homo sapiens cytochrome P-450 II C
           protein.
          Length = 356

 Score = 87.0 bits (206), Expect = 7e-17
 Identities = 71/240 (29%), Positives = 114/240 (47%), Gaps = 19/240 (7%)

Query: 63  KVLHNMSNTALQQRKSVFLQEHDAASD--KPTDIILETCGGAFSDKDVREE---VDNIIF 117
           KVL N++ T    R+ V  +EH A+ D   P D I         +KD ++    ++N++ 
Sbjct: 98  KVLKNVALTRSYIREKV--KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFTIENLVI 155

Query: 118 -------AGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
                  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +D   + Y 
Sbjct: 156 TAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYT 214

Query: 171 EAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFR 229
           +AV+ E  R   + P    ++   ++K +NY  P G+  +  L  V        + + F 
Sbjct: 215 DAVVHEVQRYIDLIPTSLPHAVTCDIKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFD 274

Query: 230 PERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
           P  +L E       ++F  FS G+R C+G+  A M +   L+F+L+ + + S  D  DL+
Sbjct: 275 PRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 334


>M61858-1|AAA52145.1|  370|Homo sapiens CYP2C17 protein.
          Length = 370

 Score = 86.6 bits (205), Expect = 1e-16
 Identities = 57/188 (30%), Positives = 92/188 (48%), Gaps = 5/188 (2%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +   V ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 162 FTVESLIATVTDMFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQ 220

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   +VK +NY  P G+  +  L  V      
Sbjct: 221 DRSHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 280

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E       ++F  FS G+R C+G+  A M +   L+F+L+ + + S
Sbjct: 281 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKS 340

Query: 281 --DVTDLE 286
             D  DL+
Sbjct: 341 LIDPKDLD 348


>M61854-1|AAB59426.1|  490|Homo sapiens cytochrome protein.
          Length = 490

 Score = 85.8 bits (203), Expect = 2e-16
 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           +++ AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +D   + Y +AV
Sbjct: 293 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRGHMPYTDAV 351

Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P    ++   +VK +NY  P G+  +  L  V        + + F P  
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 411

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
           +L E       ++F  FS G+R C+G+  A M +   L+F+L+ + + S  D  DL+
Sbjct: 412 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 468


>L39102-1|AAL31348.1|  217|Homo sapiens S-mephenytoin 4-hydroxylase
           protein.
          Length = 217

 Score = 85.8 bits (203), Expect = 2e-16
 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           +++ AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +D   + Y +AV
Sbjct: 20  DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRGHMPYTDAV 78

Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P    ++   +VK +NY  P G+  +  L  V        + + F P  
Sbjct: 79  VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 138

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
           +L E       ++F  FS G+R C+G+  A M +   L+F+L+ + + S  D  DL+
Sbjct: 139 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 195


>X13930-1|CAA32118.1|  494|Homo sapiens protein ( Human CYP2A4 mRNA
           for P-450 IIA4 protein. ).
          Length = 494

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>X13929-1|CAA32117.1|  448|Homo sapiens P-450 IIA3 protein (1 is 3rd
           base in codon) protein.
          Length = 448

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 251 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 309

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 310 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 369

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 370 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 418


>M33318-1|AAA52067.1|  494|Homo sapiens CYP2A protein.
          Length = 494

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>L07093-1|AAA36660.1|  468|Homo sapiens cytochrome P450 protein.
          Length = 468

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           +++ AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +D   + Y +AV
Sbjct: 271 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYTDAV 329

Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P    ++   +VK +NY  P G+  +  L  V        + + F P  
Sbjct: 330 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 389

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
           +L E       ++F  FS G+R C+G+  A M +   L+F+L+ + + S  D  DL+
Sbjct: 390 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 446


>BC096256-1|AAH96256.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>BC096255-1|AAH96255.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>BC096254-1|AAH96254.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>BC096253-1|AAH96253.3|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>AY796203-1|AAV41877.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           +++ AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +D   + Y +AV
Sbjct: 293 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYTDAV 351

Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P    ++   +VK +NY  P G+  +  L  V        + + F P  
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 411

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
           +L E       ++F  FS G+R C+G+  A M +   L+F+L+ + + S  D  DL+
Sbjct: 412 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 468


>AL583836-2|CAH74068.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           +++ AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +D   + Y +AV
Sbjct: 293 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYTDAV 351

Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P    ++   +VK +NY  P G+  +  L  V        + + F P  
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 411

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
           +L E       ++F  FS G+R C+G+  A M +   L+F+L+ + + S  D  DL+
Sbjct: 412 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 468


>AL133513-2|CAH73444.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           +++ AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +D   + Y +AV
Sbjct: 293 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYTDAV 351

Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P    ++   +VK +NY  P G+  +  L  V        + + F P  
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 411

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
           +L E       ++F  FS G+R C+G+  A M +   L+F+L+ + + S  D  DL+
Sbjct: 412 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 468


>AK090886-1|BAC03539.1|  337|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
           Homo sapiens cholesterol 24-hydroxylase mRNA. ).
          Length = 337

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 67/225 (29%), Positives = 111/225 (49%), Gaps = 14/225 (6%)

Query: 51  RTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEHDAASDKPTDIILETCGGAFSDKDVRE 110
           R +L+E  + I + L  +    +Q+R+    +  +  +D  T I L+   GA  D+ + +
Sbjct: 84  RKQLREVRESI-RFLRQVGRDWVQRRREALKRGEEVPADILTQI-LKAEEGAQDDEGLLD 141

Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
                  AGH+T +  L   +  L   P++  ++  EV  V+G ++R +  ED  RL+YL
Sbjct: 142 NFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDLGRLQYL 200

Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
             VLKES+R+YP A    R  + E  +         GF   + G  +   +  D   F P
Sbjct: 201 SQVLKESLRLYPPAWGTFRLLEEETLI--------DGFSTYVMG--RMDTYFEDPLTFNP 250

Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
           +R+   A  P  ++F  FS G RSCIG+ +A M +K  ++ LL+R
Sbjct: 251 DRFGPGAPKPRFTYFP-FSLGHRSCIGQQFAQMEVKVVMAKLLQR 294


>AF182275-1|AAF13600.1|  494|Homo sapiens cytochrome P450-2A6
           protein.
          Length = 494

 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>M33317-1|AAA52138.1|  494|Homo sapiens CYP2A protein.
          Length = 494

 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+  AG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRTKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L +         F  FS G+R C G+  A M +    + +++ +R+ S
Sbjct: 416 FLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLKS 464


>BC117165-1|AAI17166.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 7 protein.
          Length = 494

 Score = 85.0 bits (201), Expect = 3e-16
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+  AG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L +         F  FS G+R C G+  A M +    + +++ +R+ S
Sbjct: 416 FLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLKS 464


>X13897-1|CAA32097.1|  489|Homo sapiens protein ( Human mRNA for
           cytochrome P-450IIA. ).
          Length = 489

 Score = 83.8 bits (198), Expect = 7e-16
 Identities = 49/169 (28%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP+V+ +V+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 292 NLFIGGTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 350

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 351 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 410

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R+C G+  A M +    + +++ +R+ S
Sbjct: 411 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 459


>S46963-1|AAB23864.2|  477|Homo sapiens cytochrome P-450 protein.
          Length = 477

 Score = 83.4 bits (197), Expect = 9e-16
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 269 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 327

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 328 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 387

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 388 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 447


>M21940-1|AAA52159.1|  383|Homo sapiens CYP2C protein.
          Length = 383

 Score = 83.4 bits (197), Expect = 9e-16
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 175 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 233

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 234 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 293

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 294 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 353


>D00173-1|BAA00123.1|  487|Homo sapiens cytochrome P-450 protein.
          Length = 487

 Score = 83.4 bits (197), Expect = 9e-16
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 279 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 337

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 338 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 397

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 398 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 457


>BC125054-1|AAI25055.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 9 protein.
          Length = 490

 Score = 83.4 bits (197), Expect = 9e-16
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 340

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460


>AY702706-1|AAT94065.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 9 protein.
          Length = 490

 Score = 83.4 bits (197), Expect = 9e-16
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 340

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460


>AY341248-1|AAP88931.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 9 protein.
          Length = 490

 Score = 83.4 bits (197), Expect = 9e-16
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 340

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460


>AL359672-1|CAH71303.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 9 protein.
          Length = 490

 Score = 83.4 bits (197), Expect = 9e-16
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 340

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460


>M33388-1|AAA53500.1|  497|Homo sapiens cytochrome P450 IID6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>M33189-1|AAA35737.1|  500|Homo sapiens protein ( Human debrisoquine
           4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
           cds. ).
          Length = 500

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 292 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 350

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 351 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 410

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 411 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 470


>M24499-1|AAA36403.1|  373|Homo sapiens cytochrome P450db1 protein.
          Length = 373

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 165 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 223

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 224 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 283

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 284 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 343


>DQ282154-1|ABB77902.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282152-1|ABB77900.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282151-1|ABB77899.1|  496|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 496

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 288 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 346

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 347 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 406

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 407 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 466


>DQ282146-1|ABB77897.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282145-1|ABB77896.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282144-1|ABB77895.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ211354-2|ABB01372.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ211353-2|ABB01371.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ211353-1|ABB01370.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>BC132767-1|AAI32768.1|  544|Homo sapiens cytochrome P450, family 2,
           subfamily U, polypeptide 1 protein.
          Length = 544

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 5/157 (3%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           + ++  AG DT +  L   L  +  +PDVQ+KV+ E+ RV+G A R  +  D  ++ Y E
Sbjct: 346 IGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIG-ANRAPSLTDKAQMPYTE 404

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQH-RIWGADADQFR 229
           A + E  R+  V P+ I   +     L+ YT P G+  +  LW VH+   IW    D F 
Sbjct: 405 ATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPED-FY 463

Query: 230 PERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSM 265
           P R+L +   L     F  F  G+R C+G+  A M +
Sbjct: 464 PNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMEL 500


>BC075024-1|AAH75024.1|  497|Homo sapiens cytochrome P450, family 2,
           subfamily D, polypeptide 6 protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>BC075023-1|AAH75023.1|  497|Homo sapiens cytochrome P450, family 2,
           subfamily D, polypeptide 6 protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>AY545216-1|AAS55001.1|  497|Homo sapiens cytochrome P4502D6
           protein.
          Length = 497

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>AY343323-1|AAQ21380.1|  544|Homo sapiens cytochrome P450 protein.
          Length = 544

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 5/157 (3%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           + ++  AG DT +  L   L  +  +PDVQ+KV+ E+ RV+G A R  +  D  ++ Y E
Sbjct: 346 IGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIG-ANRAPSLTDKAQMPYTE 404

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQH-RIWGADADQFR 229
           A + E  R+  V P+ I   +     L+ YT P G+  +  LW VH+   IW    D F 
Sbjct: 405 ATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPED-FY 463

Query: 230 PERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSM 265
           P R+L +   L     F  F  G+R C+G+  A M +
Sbjct: 464 PNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMEL 500


>AB209492-1|BAD92729.1|  566|Homo sapiens Debrisoquine 4-hydroxylase
           mutant allele variant protein.
          Length = 566

 Score = 83.0 bits (196), Expect = 1e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 358 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 416

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 417 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 476

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 477 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 536


>U37143-1|AAC50370.2|  502|Homo sapiens cytochrome P450
           monooxygenase CYP2J2 protein.
          Length = 502

 Score = 82.6 bits (195), Expect = 2e-15
 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           ++ FAG +T ST L  AL  +  +P++Q+KV  E+ RV+G  ++  T      + Y  AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAV 365

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  RM  + P+ + R    +  L  Y  P G+  +  L  +H+     A  D F P+ 
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425

Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
           +LE         F  FS G+R+C+G+  A   +    + L++++     +++   L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485

Query: 290 EAILRP 295
              + P
Sbjct: 486 GITISP 491


>U22029-1|AAB40520.1|  494|Homo sapiens cytochrome P450 protein.
          Length = 494

 Score = 82.6 bits (195), Expect = 2e-15
 Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+  AG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRTKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDLRFFSNPRDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS  +R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLGEKGQFKKRDAFVPFSIRKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>M21939-1|AAA52158.1|  485|Homo sapiens CYP2C protein.
          Length = 485

 Score = 82.6 bits (195), Expect = 2e-15
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 277 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 335

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 336 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 395

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 396 FPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 455


>M15331-1|AAA52157.1|  485|Homo sapiens CYP2C protein.
          Length = 485

 Score = 82.6 bits (195), Expect = 2e-15
 Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)

Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
           F+ + +     ++  AG +T ST L  AL LL  HP+V  KV  E+ RV+G   R    +
Sbjct: 277 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 335

Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           D   + Y +AV+ E  R   + P    ++   ++K +NY  P G+  ++ L  V      
Sbjct: 336 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 395

Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
             + + F P  +L E        +F  FS G+R C+G+  A M +   L+ +L+ + + S
Sbjct: 396 FPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 455


>BC032594-1|AAH32594.1|  502|Homo sapiens cytochrome P450, family 2,
           subfamily J, polypeptide 2 protein.
          Length = 502

 Score = 82.6 bits (195), Expect = 2e-15
 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           ++ FAG +T ST L  AL  +  +P++Q+KV  E+ RV+G  ++  T      + Y  AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAV 365

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  RM  + P+ + R    +  L  Y  P G+  +  L  +H+     A  D F P+ 
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425

Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
           +LE         F  FS G+R+C+G+  A   +    + L++++     +++   L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485

Query: 290 EAILRP 295
              + P
Sbjct: 486 GITISP 491


>AY426985-1|AAQ93356.1|  502|Homo sapiens cytochrome P450, family 2,
           subfamily J, polypeptide 2 protein.
          Length = 502

 Score = 82.6 bits (195), Expect = 2e-15
 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           ++ FAG +T ST L  AL  +  +P++Q+KV  E+ RV+G  ++  T      + Y  AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAV 365

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  RM  + P+ + R    +  L  Y  P G+  +  L  +H+     A  D F P+ 
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425

Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
           +LE         F  FS G+R+C+G+  A   +    + L++++     +++   L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485

Query: 290 EAILRP 295
              + P
Sbjct: 486 GITISP 491


>AF272142-1|AAM44456.1|  502|Homo sapiens cytochrome P450 protein.
          Length = 502

 Score = 82.6 bits (195), Expect = 2e-15
 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           ++ FAG +T ST L  AL  +  +P++Q+KV  E+ RV+G  ++  T      + Y  AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAV 365

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  RM  + P+ + R    +  L  Y  P G+  +  L  +H+     A  D F P+ 
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425

Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
           +LE         F  FS G+R+C+G+  A   +    + L++++     +++   L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485

Query: 290 EAILRP 295
              + P
Sbjct: 486 GITISP 491


>X08006-1|CAA30807.1|  497|Homo sapiens cytochrome P450 db1 protein.
          Length = 497

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>M20403-1|AAA52153.1|  497|Homo sapiens CYP2D protein.
          Length = 497

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++R  V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>AY513608-1|AAR90939.1|  494|Homo sapiens cytochrome P450 2A13
           variant 5 protein.
          Length = 494

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+ FAG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P+ +A   + + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415

Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L+          F  FS G+R C G+  A M +    + +++ +R  S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464


>AY513606-1|AAR90937.1|  494|Homo sapiens cytochrome P450 2A13
           variant 3 protein.
          Length = 494

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+ FAG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P+ +A   + + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415

Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L+          F  FS G+R C G+  A M +    + +++ +R  S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464


>AY513605-1|AAR90936.1|  494|Homo sapiens cytochrome P450 2A13
           variant 2 protein.
          Length = 494

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+ FAG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P+ +A   + + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415

Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L+          F  FS G+R C G+  A M +    + +++ +R  S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464


>AY513604-1|AAR90935.1|  494|Homo sapiens cytochrome P450 2A13
           variant 1 protein.
          Length = 494

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+ FAG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P+ +A   + + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415

Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L+          F  FS G+R C G+  A M +    + +++ +R  S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464


>AF209774-1|AAG35775.1|  494|Homo sapiens cytochrome P450 2A13
           protein.
          Length = 494

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+ FAG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P+ +A   + + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415

Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L+          F  FS G+R C G+  A M +    + +++ +R  S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464


>AB080265-1|BAB85489.1|  502|Homo sapiens cytochrome P450 2J2
           protein.
          Length = 502

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           ++ FAG +T ST L  AL  +  +P++Q+KV  E+ RV+G  ++  T      + Y  AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQQPSTAARE-SMPYTNAV 365

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  RM  + P+ + R    +  L  Y  P G+  +  L  +H+     A  D F P+ 
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425

Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
           +LE         F  FS G+R+C+G+  A   +    + L++++     +++   L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485

Query: 290 EAILRP 295
              + P
Sbjct: 486 GITISP 491


>BC100982-1|AAI00983.1|  280|Homo sapiens CYP3A43 protein protein.
          Length = 280

 Score = 81.4 bits (192), Expect = 4e-15
 Identities = 61/230 (26%), Positives = 110/230 (47%), Gaps = 12/230 (5%)

Query: 9   LGIKMEDHSAVNQQYEQALHDIF--AVLTERFQKFW-LHYDFVYNRTKLKEREDQIIKVL 65
           LG   +   +++++YE+A    F  ++ T   Q    L       R+ L E     ++V+
Sbjct: 55  LGFSQQSTRSLSEKYEEAFKIGFFGSLFTLNIQSLAVLPRPECMVRSGLTETSTSWVRVI 114

Query: 66  ---HNMSNTALQQRKSVFLQEHDAASDKPTDIILETCGGAFSDKDVREEVDNIIFAGHDT 122
                     LQ R   F Q  D+ + K T         A SD ++  +   IIFA +DT
Sbjct: 115 LLPQPPEELGLQHRVDFFQQIIDSQNSKETK-----SHKALSDLELVAQSIIIIFAAYDT 169

Query: 123 ISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYP 182
            ST L   +  L +HPDVQ K+  E+  VL + +  VT +  +++EYL+ V+ E++R++P
Sbjct: 170 TSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTYDALVQMEYLDMVVNETLRLFP 228

Query: 183 VAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           V   + R    ++++     P G   ++ ++ +H    +  + ++F PER
Sbjct: 229 VVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 278


>U22027-1|AAB40518.1|  494|Homo sapiens cytochrome P450 protein.
          Length = 494

 Score = 81.0 bits (191), Expect = 5e-15
 Identities = 50/169 (29%), Positives = 85/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+  AG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y+EAV
Sbjct: 297 NLFIAGTETVSTTLHYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+ +AR    + K +++  P G     +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGIEVFPMLGSVLRDLRFFSNPRDFNPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS  +R+C G+  A M +    + +++ +R+ S
Sbjct: 416 FLGEKGQFKKRDAFVPFSIRKRNCFGEGLARMELFLFFTTVMQNFRLKS 464


>AY513609-1|AAR90940.1|  494|Homo sapiens cytochrome P450 2A13
           variant 6 protein.
          Length = 494

 Score = 81.0 bits (191), Expect = 5e-15
 Identities = 48/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+ FAG +T+ST L     LL  HP+++ KV+ E+ RV+G   R    ED  ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPELEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P+ +A   + + K +++  P G+    +L  V +   + ++   F P+ 
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415

Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L+          F  FS G+R C G+  A M +    + +++ +R  S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464


>AJ563378-3|CAD91347.1|  173|Homo sapiens hypothetical protein
           protein.
          Length = 173

 Score = 81.0 bits (191), Expect = 5e-15
 Identities = 42/150 (28%), Positives = 82/150 (54%), Gaps = 3/150 (2%)

Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHR 219
           T +  +++EYL+ V+ E++R++PVA  + R    +V++     P GS  ++  + +H   
Sbjct: 17  TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDP 76

Query: 220 IWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
            +  + ++FRPER+ +     DP  +  F TG R+CIG  +A+M+MK  L  +L+ +   
Sbjct: 77  KYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 136

Query: 280 -SDVTDLEFKL--EAILRPHRGHYIAIERR 306
               T +  KL  + +L+P +   + ++ R
Sbjct: 137 PCKETQIPLKLDTQGLLQPEKPIVLKVDSR 166


>AJ563378-2|CAD91647.1|  160|Homo sapiens cytochrome P450 protein.
          Length = 160

 Score = 81.0 bits (191), Expect = 5e-15
 Identities = 42/150 (28%), Positives = 82/150 (54%), Gaps = 3/150 (2%)

Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHR 219
           T +  +++EYL+ V+ E++R++PVA  + R    +V++     P GS  ++  + +H   
Sbjct: 4   TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDP 63

Query: 220 IWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
            +  + ++FRPER+ +     DP  +  F TG R+CIG  +A+M+MK  L  +L+ +   
Sbjct: 64  KYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 123

Query: 280 -SDVTDLEFKL--EAILRPHRGHYIAIERR 306
               T +  KL  + +L+P +   + ++ R
Sbjct: 124 PCKETQIPLKLDTQGLLQPEKPIVLKVDSR 153


>D12621-1|BAA02145.1|  389|Homo sapiens cytochrome P-450LTBV
           protein.
          Length = 389

 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 49/170 (28%), Positives = 93/170 (54%), Gaps = 13/170 (7%)

Query: 22  QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
           +Y  A+ ++ A++T+R Q+  L+ DF+Y  T   +R  +  +++H+ ++  +Q+R+    
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279

Query: 80  ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
                 FLQ    +      D++L   +  G   SD+D+R E D  +F GHDT ++ L+ 
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339

Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESM 178
            L  L  HP+ Q++   EV+ +L D E +++  +D  +L +L   +KES+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESL 389


>BC106758-1|AAI06759.1|  497|Homo sapiens cytochrome P450, family 2,
           subfamily D, polypeptide 6 protein.
          Length = 497

 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282162-1|ABB77909.1|  500|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 500

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 292 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 350

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 351 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 410

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 411 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 470


>DQ282160-1|ABB77908.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282159-1|ABB77907.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282158-1|ABB77906.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282157-1|ABB77905.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282156-1|ABB77904.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282155-1|ABB77903.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>DQ282147-1|ABB77898.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>CR456430-1|CAG30316.1|  446|Homo sapiens CYP2D6 protein.
          Length = 446

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 357 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416


>BC126858-1|AAI26859.1|  497|Homo sapiens cytochrome P450, family 2,
           subfamily D, polypeptide 6 protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>BC106757-1|AAI06758.1|  446|Homo sapiens cytochrome P450, family 2,
           subfamily D, polypeptide 6 protein.
          Length = 446

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 357 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416


>BC067432-1|AAH67432.1|  497|Homo sapiens cytochrome P450, family 2,
           subfamily D, polypeptide 6 protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>BC066877-1|AAH66877.1|  446|Homo sapiens CYP2D6 protein protein.
          Length = 446

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  V+G   R    
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 357 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416


>BC067433-1|AAH67433.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 50/183 (27%), Positives = 89/183 (48%), Gaps = 3/183 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           V ++ FAG +T ST L   L +L  +P++++K++ E+ RV+G +     K D   + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           AV++E  R   + P  +   +  +   + Y  P G+  +  L  V        D ++F+P
Sbjct: 352 AVVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           E +L E        +F  FSTG+R C G+  A M +   L  +L+ + +   V   +  L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471

Query: 290 EAI 292
             I
Sbjct: 472 SPI 474


>DQ282153-1|ABB77901.1|  497|Homo sapiens cytochrome P450 2D6
           protein.
          Length = 497

 Score = 78.6 bits (185), Expect = 3e-14
 Identities = 51/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           +F+D+++   V ++  AG  T ST L   L L+  HPDVQ +V  E+  ++G   R    
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDMIGQVRRP-EM 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
            D   + Y  AV+ E  R   + P+ +   +  +++++ +  P G+  I  L  V +   
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407

Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
                 +F PE +L+A      P  F  FS GRR+C+G+  A M +    + LL+ +  S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467


>BC033691-1|AAH33691.1|  504|Homo sapiens cytochrome P450, family 2,
           subfamily S, polypeptide 1 protein.
          Length = 504

 Score = 78.6 bits (185), Expect = 3e-14
 Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 5/184 (2%)

Query: 100 GGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV 159
           G  F++K++   V  ++FAG  T+ST +   L LL  +P VQ  V  E+ R LG A +  
Sbjct: 284 GTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG-AGQAP 342

Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGV-HQ 217
           +  D  RL Y +AVL E+ R+  + P+ I R      + + YT P G+    LL  + H 
Sbjct: 343 SLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHD 402

Query: 218 HRIWGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
             I+    ++F P+R+L+A         F  FS G+R C+G+  A   +    + +L+ +
Sbjct: 403 PNIF-KHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAF 461

Query: 277 RVSS 280
            + S
Sbjct: 462 SLES 465


>AY358603-1|AAQ88966.1|  504|Homo sapiens Cytochrome p450 protein.
          Length = 504

 Score = 78.6 bits (185), Expect = 3e-14
 Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 5/184 (2%)

Query: 100 GGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV 159
           G  F++K++   V  ++FAG  T+ST +   L LL  +P VQ  V  E+ R LG A +  
Sbjct: 284 GTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG-AGQAP 342

Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGV-HQ 217
           +  D  RL Y +AVL E+ R+  + P+ I R      + + YT P G+    LL  + H 
Sbjct: 343 SLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHD 402

Query: 218 HRIWGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
             I+    ++F P+R+L+A         F  FS G+R C+G+  A   +    + +L+ +
Sbjct: 403 PNIF-KHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAF 461

Query: 277 RVSS 280
            + S
Sbjct: 462 SLES 465


>AK027605-1|BAB55227.1|  564|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14699 fis, clone NT2RP2006571, moderately
           similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
          Length = 564

 Score = 78.6 bits (185), Expect = 3e-14
 Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 5/184 (2%)

Query: 100 GGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV 159
           G  F++K++   V  ++FAG  T+ST +   L LL  +P VQ  V  E+ R LG A +  
Sbjct: 284 GTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG-AGQAP 342

Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGV-HQ 217
           +  D  RL Y +AVL E+ R+  + P+ I R      + + YT P G+    LL  + H 
Sbjct: 343 SLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHD 402

Query: 218 HRIWGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
             I+    ++F P+R+L+A         F  FS G+R C+G+  A   +    + +L+ +
Sbjct: 403 PNIF-KHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAF 461

Query: 277 RVSS 280
            + S
Sbjct: 462 SLES 465


>AF335278-1|AAK13498.1|  504|Homo sapiens cytochrome P450 2S1
           protein.
          Length = 504

 Score = 78.6 bits (185), Expect = 3e-14
 Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 5/184 (2%)

Query: 100 GGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV 159
           G  F++K++   V  ++FAG  T+ST +   L LL  +P VQ  V  E+ R LG A +  
Sbjct: 284 GTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG-AGQAP 342

Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGV-HQ 217
           +  D  RL Y +AVL E+ R+  + P+ I R      + + YT P G+    LL  + H 
Sbjct: 343 SLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHD 402

Query: 218 HRIWGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
             I+    ++F P+R+L+A         F  FS G+R C+G+  A   +    + +L+ +
Sbjct: 403 PNIF-KHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAF 461

Query: 277 RVSS 280
            + S
Sbjct: 462 SLES 465


>AF280110-1|AAG33011.1|  420|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 420

 Score = 78.6 bits (185), Expect = 3e-14
 Identities = 40/131 (30%), Positives = 74/131 (56%), Gaps = 1/131 (0%)

Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
           A SD ++  +   IIFA +DT ST L   +  L +HPDVQ K+  E+  VL + +  VT 
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347

Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
           +  +++EYL+ V+ E++R++PV   + R    ++++     P G   ++ ++ +H    +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407

Query: 222 GADADQFRPER 232
             + ++F PER
Sbjct: 408 WTEPEKFCPER 418


>U22028-1|AAB40519.1|  494|Homo sapiens cytochrome P450 protein.
          Length = 494

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 48/169 (28%), Positives = 83/169 (49%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+ FAG +T+ST L     LL  HP+V+ KV+ E+ RV+G   R    ED  ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355

Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   + P+ +A   + + K +++  P G+    +L    +   + ++     P+ 
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSELRDPRFFSNPQDCSPQH 415

Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           +L E         F  FS G+R C G+  A M +    + +++ +R  S
Sbjct: 416 FLDEKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464


>K03192-1|AAA52147.1|  331|Homo sapiens CYP1A1 protein.
          Length = 331

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 49/169 (28%), Positives = 83/169 (49%), Gaps = 3/169 (1%)

Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
           N+   G +T+ST L     LL  HP V+ KV+ E+ RV+G   R    ED  ++ Y+EA+
Sbjct: 134 NLFIGGTETVSTTLRYGFLLLIKHPGVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAM 192

Query: 174 LKESMRMYPVAPVI-ARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
           + E  R   V P+I       + K +++  P G+    +L  V +  I+ +    F P+ 
Sbjct: 193 IHEIQRFGDVIPMIWPGRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPIFLSKPQDFNPQH 252

Query: 233 WLEAATLPDPS-FFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
           + E    P  S  F  FS G+ +C G+  A M +    + +++ +R+ S
Sbjct: 253 FTELEGAPKKSDAFVPFSIGQPNCFGEGLARMELFLFFTTVMQNFRLKS 301


>J02843-1|AAA52155.1|  493|Homo sapiens protein ( Human cytochrome
           P450IIE1 (ethanol-inducible) gene, complete cds. ).
          Length = 493

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           V ++ FAG +T ST L   L +L  +P++++K++ E+ RV+G +     K D   + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           AV+ E  R   + P  +   +  +   + Y  P G+  +  L  V        D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           E +L E        +F  FSTG+R C G+  A M +   L  +L+ + +   V   +  L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471

Query: 290 EAI 292
             I
Sbjct: 472 SPI 474


>J02625-1|AAA35743.1|  493|Homo sapiens protein ( Human cytochrome
           P-450j mRNA, complete cds. ).
          Length = 493

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           V ++ FAG +T ST L   L +L  +P++++K++ E+ RV+G +     K D   + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           AV+ E  R   + P  +   +  +   + Y  P G+  +  L  V        D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           E +L E        +F  FSTG+R C G+  A M +   L  +L+ + +   V   +  L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471

Query: 290 EAI 292
             I
Sbjct: 472 SPI 474


>DQ515958-1|ABF47105.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           V ++ FAG +T ST L   L +L  +P++++K++ E+ RV+G +     K D   + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           AV+ E  R   + P  +   +  +   + Y  P G+  +  L  V        D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           E +L E        +F  FSTG+R C G+  A M +   L  +L+ + +   V   +  L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471

Query: 290 EAI 292
             I
Sbjct: 472 SPI 474


>DQ149222-1|AAZ77710.1|  493|Homo sapiens cytochrome P450 2E1
           protein.
          Length = 493

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           V ++ FAG +T ST L   L +L  +P++++K++ E+ RV+G +     K D   + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           AV+ E  R   + P  +   +  +   + Y  P G+  +  L  V        D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           E +L E        +F  FSTG+R C G+  A M +   L  +L+ + +   V   +  L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471

Query: 290 EAI 292
             I
Sbjct: 472 SPI 474


>AL161645-2|CAH70047.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           V ++ FAG +T ST L   L +L  +P++++K++ E+ RV+G +     K D   + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           AV+ E  R   + P  +   +  +   + Y  P G+  +  L  V        D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           E +L E        +F  FSTG+R C G+  A M +   L  +L+ + +   V   +  L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471

Query: 290 EAI 292
             I
Sbjct: 472 SPI 474


>AF233625-1|AAF99279.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 59/199 (29%), Positives = 97/199 (48%), Gaps = 12/199 (6%)

Query: 116 IFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLE----YLE 171
           + AG++ I+  L+ A  LL ++PD Q+K+  EV       E+ +  E +  LE    YL+
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVF---KEKHMAPE-FCSLEEGLPYLD 395

Query: 172 AVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPE 231
            V+ E++RMYP A    R +  + ++     PAG+   + +  +H         + F PE
Sbjct: 396 MVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPE 455

Query: 232 RW-LEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS-DVTDLEFKL 289
           R+  EA     P  +  F  G RSC+G    ++ +K TL  +L ++R  +   T +  +L
Sbjct: 456 RFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQL 515

Query: 290 E--AILRPHRGHYIAIERR 306
           E  + L P  G YI I  R
Sbjct: 516 ESKSALGPKNGVYIKIVSR 534


>AF182276-1|AAF13601.1|  493|Homo sapiens cytochrome P450-2E1
           protein.
          Length = 493

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           V ++ FAG +T ST L   L +L  +P++++K++ E+ RV+G +     K D   + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           AV+ E  R   + P  +   +  +   + Y  P G+  +  L  V        D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           E +L E        +F  FSTG+R C G+  A M +   L  +L+ + +   V   +  L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471

Query: 290 EAI 292
             I
Sbjct: 472 SPI 474


>AF084225-1|AAD13753.1|  462|Homo sapiens cytochrome P450 2E1
           protein.
          Length = 462

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)

Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
           V ++ FAG +T ST L   L +L  +P++++K++ E+ RV+G +     K D   + Y++
Sbjct: 262 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 320

Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
           AV+ E  R   + P  +   +  +   + Y  P G+  +  L  V        D ++F+P
Sbjct: 321 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 380

Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
           E +L E        +F  FSTG+R C G+  A M +   L  +L+ + +   V   +  L
Sbjct: 381 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 440

Query: 290 EAI 292
             I
Sbjct: 441 SPI 443


>AF233624-1|AAF99278.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 77.8 bits (183), Expect = 5e-14
 Identities = 59/199 (29%), Positives = 97/199 (48%), Gaps = 12/199 (6%)

Query: 116 IFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLE----YLE 171
           + AG++ I+  L+ A  LL ++PD Q+K+  EV       E+ +  E +  LE    YL+
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVF---KEKHMAPE-FCSLEEGLPYLD 395

Query: 172 AVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPE 231
            V+ E++RMYP A    R +  + ++     PAG+   + +  +H         + F PE
Sbjct: 396 MVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPENFNPE 455

Query: 232 RW-LEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS-DVTDLEFKL 289
           R+  EA     P  +  F  G RSC+G    ++ +K TL  +L ++R  +   T +  +L
Sbjct: 456 RFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQL 515

Query: 290 E--AILRPHRGHYIAIERR 306
           E  + L P  G YI I  R
Sbjct: 516 ESKSALGPKNGVYIKIVSR 534


>M80647-1|AAA60618.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 77.4 bits (182), Expect = 6e-14
 Identities = 59/199 (29%), Positives = 97/199 (48%), Gaps = 12/199 (6%)

Query: 116 IFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLE----YLE 171
           + AG++ I+  L+ A  LL ++PD Q+K+  EV       E+ +  E +  LE    YL+
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVF---KEKHMAPE-FCSLEEGLPYLD 395

Query: 172 AVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPE 231
            V+ E++RMYP A    R +  + ++     PAG+   + +  +H         + F PE
Sbjct: 396 MVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPE 455

Query: 232 RW-LEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS-DVTDLEFKL 289
           R+  EA     P  +  F  G RSC+G    ++ +K TL  +L ++R  +   T +  +L
Sbjct: 456 RFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQL 515

Query: 290 E--AILRPHRGHYIAIERR 306
           E  + L P  G YI I  R
Sbjct: 516 ESKSALGPKNGVYIKIVSR 534


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.321    0.135    0.396 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 43,133,013
Number of Sequences: 224733
Number of extensions: 1712603
Number of successful extensions: 4188
Number of sequences better than 10.0: 429
Number of HSP's better than 10.0 without gapping: 386
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 3092
Number of HSP's gapped (non-prelim): 457
length of query: 311
length of database: 73,234,838
effective HSP length: 90
effective length of query: 221
effective length of database: 53,008,868
effective search space: 11714959828
effective search space used: 11714959828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 65 (30.3 bits)