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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= tesV0244.Seq
         (797 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila melanogaste...    97   3e-19
UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:...    94   4e-18
UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole car...    89   9e-17
UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep: LO...    77   5e-13
UniRef50_A5UWC5 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    50   5e-05
UniRef50_Q8TX83 Cluster: Phosphoribosylaminoimidazole-succinocar...    42   0.014
UniRef50_A6QAA3 Cluster: Phosphoribosylaminoimidazole-succinocar...    41   0.031
UniRef50_Q73PW0 Cluster: Phosphoribosylaminoimidazole-succinocar...    38   0.39 
UniRef50_A4SAQ9 Cluster: Phosphoribosylaminoimidazole-succinocar...    37   0.51 
UniRef50_O57978 Cluster: Phosphoribosylaminoimidazole-succinocar...    37   0.51 
UniRef50_Q7M9X5 Cluster: Phosphoribosylaminoimidazole-succinocar...    37   0.67 
UniRef50_Q58987 Cluster: Phosphoribosylaminoimidazole-succinocar...    36   0.89 
UniRef50_Q92AN6 Cluster: Phosphoribosylaminoimidazole-succinocar...    36   0.89 
UniRef50_UPI00015BB105 Cluster: phosphoribosylaminoimidazole-suc...    36   1.2  
UniRef50_P12046 Cluster: Phosphoribosylaminoimidazole-succinocar...    35   2.7  
UniRef50_Q9X0X0 Cluster: Phosphoribosylaminoimidazole-succinocar...    34   4.8  
UniRef50_Q49WJ0 Cluster: Phosphoribosylaminoimidazole-succinocar...    33   8.3  

>UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila
           melanogaster|Rep: CG17024-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 395

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 38/68 (55%), Positives = 56/68 (82%)
 Frame = +3

Query: 255 DPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV 434
           DP W +EQI+S+ F  NGL+IG DEV  MR+ ++++FE+LE+AW  ++CAL+DMK+EFGV
Sbjct: 139 DPLWCDEQILSSNFECNGLIIGADEVQIMRRTSLVVFEVLERAWKTKNCALVDMKVEFGV 198

Query: 435 DTEGSIVL 458
           D +G+I+L
Sbjct: 199 DEDGNILL 206


>UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:
           Phosphoribosylaminoimidazole- succinocarboxamide
           synthase (EC 6.3.2.6) (SAICAR synthetase);
           Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
           (AIR carboxylase) (AIRC)]; n=60; Eumetazoa|Rep:
           Multifunctional protein ADE2 [Includes:
           Phosphoribosylaminoimidazole- succinocarboxamide
           synthase (EC 6.3.2.6) (SAICAR synthetase);
           Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
           (AIR carboxylase) (AIRC)] - Homo sapiens (Human)
          Length = 425

 Score = 93.9 bits (223), Expect = 4e-18
 Identities = 46/69 (66%), Positives = 54/69 (78%), Gaps = 1/69 (1%)
 Frame = +3

Query: 255 DPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV 434
           DPQWSEEQ+I+AKF + GLLIG+ EVD M  AT  IFEILEK+W  ++C L+DMKIEFGV
Sbjct: 137 DPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGV 196

Query: 435 D-TEGSIVL 458
           D T   IVL
Sbjct: 197 DVTTKEIVL 205


>UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole
           carboxylase, phosphoribosylaminoimidazole
           succinocarboxamide synthetase; n=2; Coelomata|Rep:
           phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoimidazole succinocarboxamide
           synthetase - Bos Taurus
          Length = 402

 Score = 89.4 bits (212), Expect = 9e-17
 Identities = 40/61 (65%), Positives = 49/61 (80%)
 Frame = +3

Query: 255 DPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV 434
           DPQWSEEQ+I+A F + GL+IG+ EVD M  AT  IFEILEK+W  ++C L+DMKIEFGV
Sbjct: 140 DPQWSEEQLIAANFCFAGLVIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGV 199

Query: 435 D 437
           D
Sbjct: 200 D 200


>UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep:
           LOC431975 protein - Xenopus laevis (African clawed frog)
          Length = 371

 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 37/67 (55%), Positives = 51/67 (76%), Gaps = 1/67 (1%)
 Frame = +3

Query: 261 QWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVD- 437
           Q S+EQ+++ K    GLLIG+ EVD M ++TI IFEI+EKAW  +DC L+DM+I+FGVD 
Sbjct: 209 QLSKEQLMAVKLICAGLLIGKMEVDVMTRSTIAIFEIIEKAWRAQDCTLVDMRIKFGVDV 268

Query: 438 TEGSIVL 458
           T+  I+L
Sbjct: 269 TKKEILL 275


>UniRef50_A5UWC5 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
           n=5; Chloroflexi (class)|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase
           - Roseiflexus sp. RS-1
          Length = 249

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 25/68 (36%), Positives = 41/68 (60%)
 Frame = +3

Query: 255 DPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV 434
           DPQ + ++II+        +   DEV+ M   +  +F ++E+AWA +D  L D+KIEFG 
Sbjct: 131 DPQMTPDEIIAQG------IASADEVEQMASESRRVFLLIEEAWAAQDVVLCDLKIEFGR 184

Query: 435 DTEGSIVL 458
           DT G +++
Sbjct: 185 DTSGRLLV 192


>UniRef50_Q8TX83 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=6; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanopyrus kandleri
          Length = 247

 Score = 42.3 bits (95), Expect = 0.014
 Identities = 19/50 (38%), Positives = 32/50 (64%)
 Frame = +3

Query: 312 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLG 461
           L   +EV+ MR+ T+ + E+L +     D  L+D K+EFGV+ +G +V+G
Sbjct: 143 LATEEEVERMRELTLQVNEVLSEFLKDCDIILVDFKLEFGVNPDGEVVVG 192


>UniRef50_A6QAA3 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=2; Epsilonproteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Sulfurovum sp. (strain NBC37-1)
          Length = 244

 Score = 41.1 bits (92), Expect = 0.031
 Identities = 18/44 (40%), Positives = 30/44 (68%)
 Frame = +3

Query: 327 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           E+DY+R     I ++L+  +A R+  L+D K+EFG D +G+I+L
Sbjct: 153 ELDYIRYMARRINDLLKAFYAQRNLTLVDFKLEFGRDMDGNIIL 196


>UniRef50_Q73PW0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Treponema denticola|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Treponema denticola
          Length = 316

 Score = 37.5 bits (83), Expect = 0.39
 Identities = 21/70 (30%), Positives = 38/70 (54%)
 Frame = +3

Query: 249 KPDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEF 428
           K  P   +E++   +    G L  +++ D+++KA + +FE  +K+       L+D K EF
Sbjct: 149 KGGPTGHDERLTCDEVVSQGYL-SKEQWDFVQKAALALFERGQKSAKEAGLILVDTKYEF 207

Query: 429 GVDTEGSIVL 458
           GVD   +I+L
Sbjct: 208 GVDKNNNILL 217


>UniRef50_A4SAQ9 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Ostreococcus lucimarinus CCE9901|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Ostreococcus lucimarinus CCE9901
          Length = 367

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = +3

Query: 321 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           +D++DY    T+ +F   ++  A R   L+D K EFG D +G+I L
Sbjct: 222 QDDLDYCVAKTLEVFAYAQEVAATRGLILVDTKYEFGRDADGTIRL 267


>UniRef50_O57978 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=6; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pyrococcus horikoshii
          Length = 238

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 18/48 (37%), Positives = 27/48 (56%)
 Frame = +3

Query: 315 IGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           I  DE+  + +  + + EIL+   A +   L+D K+EFG D  G IVL
Sbjct: 141 ISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVL 188


>UniRef50_Q7M9X5 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=18; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Wolinella succinogenes
          Length = 236

 Score = 36.7 bits (81), Expect = 0.67
 Identities = 16/46 (34%), Positives = 30/46 (65%)
 Frame = +3

Query: 321 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           ++E++++++    I EIL   +  +   L+D K+EFG D EG+I+L
Sbjct: 146 QEELEFLKETAREINEILRSFFDSKGLNLVDFKLEFGKDIEGNILL 191


>UniRef50_Q58987 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=5; Euryarchaeota|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanococcus jannaschii
          Length = 242

 Score = 36.3 bits (80), Expect = 0.89
 Identities = 15/49 (30%), Positives = 32/49 (65%)
 Frame = +3

Query: 312 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           L  R+E++ +++  + + E+L+K +  +   L+D KIE G D EG++++
Sbjct: 148 LATREELNKIKEIALKVNEVLKKLFDEKGIILVDFKIEIGKDREGNLLV 196


>UniRef50_Q92AN6 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=17; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Listeria innocua
          Length = 237

 Score = 36.3 bits (80), Expect = 0.89
 Identities = 17/45 (37%), Positives = 30/45 (66%)
 Frame = +3

Query: 324 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           +E+D +R+A   I ++L++ +   +  LID K+EFG D  G+I+L
Sbjct: 145 NEMDTIRQAARSINKVLQELFNQMNITLIDFKLEFGRDAAGNILL 189


>UniRef50_UPI00015BB105 Cluster:
           phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Ignicoccus hospitalis KIN4/I|Rep:
           phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Ignicoccus hospitalis KIN4/I
          Length = 235

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 14/49 (28%), Positives = 30/49 (61%)
 Frame = +3

Query: 312 LIGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           ++ +D +  +R+ T+ + E+L + +      LID K+E+G+  +G +VL
Sbjct: 137 IVSKDVMKTIRETTLKVNELLTELFEKAGFKLIDFKVEYGITEDGRVVL 185


>UniRef50_P12046 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=61; Bacilli|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Bacillus subtilis
          Length = 241

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 15/45 (33%), Positives = 28/45 (62%)
 Frame = +3

Query: 324 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           ++V+ ++  T ++ E L+  +      LID K+EFG+D EG ++L
Sbjct: 148 EQVETIKSITTIVNEELQSIFDDCHVRLIDFKLEFGLDAEGQVLL 192


>UniRef50_Q9X0X0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=4; Thermotogaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Thermotoga maritima
          Length = 230

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 15/47 (31%), Positives = 30/47 (63%)
 Frame = +3

Query: 321 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLG 461
           + + + M++A + I   L++ +   +  L D+K EFG+D +G++VLG
Sbjct: 138 KKQAEKMKEAAVKITLALKEFFERANFELWDIKYEFGLDKDGNVVLG 184


>UniRef50_Q49WJ0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Staphylococcus saprophyticus subsp.
           saprophyticus ATCC 15305|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Staphylococcus saprophyticus subsp. saprophyticus
           (strain ATCC 15305 /DSM 20229)
          Length = 233

 Score = 33.1 bits (72), Expect = 8.3
 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +3

Query: 309 LLIGRD-EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVL 458
           L I  D E++ +++A   I E+L       +  L+D KIEFG   EG I+L
Sbjct: 137 LQIANDGEIEKLKEAATEINEVLVNLMDKMNLRLVDFKIEFGRTNEGEILL 187


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 579,444,992
Number of Sequences: 1657284
Number of extensions: 8638908
Number of successful extensions: 15411
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 15066
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 15409
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 68319938570
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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