SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30064
         (604 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular organ...   233   2e-60
UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-P...   207   2e-52
UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor;...   200   2e-50
UniRef50_Q39B63 Cluster: Beta-lactamase-like; n=16; Proteobacter...   162   7e-39
UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1; Acine...   151   9e-36
UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein; ...   149   5e-35
UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2; Synechococcus...   147   2e-34
UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamil...   138   7e-32
UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|R...   137   2e-31
UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily prot...   137   2e-31
UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15; Gammaprot...   137   2e-31
UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1; Can...   136   4e-31
UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; ...   130   2e-29
UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas s...   103   4e-21
UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1; She...    91   1e-17
UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteoba...    88   2e-16
UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium p...    87   3e-16
UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1; ...    85   1e-15
UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1...    84   3e-15
UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1; Syn...    81   2e-14
UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2; Thermoprot...    81   2e-14
UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor...    80   3e-14
UniRef50_Q6MNF6 Cluster: Metallo-beta-lactamase superfamily prot...    80   5e-14
UniRef50_Q0SRP5 Cluster: Metallo-beta-lactamase family protein; ...    79   6e-14
UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1...    79   6e-14
UniRef50_Q1IQE8 Cluster: Beta-lactamase-like; n=2; Acidobacteria...    79   8e-14
UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily prot...    79   8e-14
UniRef50_Q64UQ6 Cluster: Putative metallo-beta-lactamase; n=5; B...    79   1e-13
UniRef50_Q1ZAD4 Cluster: Probable metallo-beta-lactamase superfa...    79   1e-13
UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    78   1e-13
UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein; ...    78   1e-13
UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein; ...    78   1e-13
UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; ...    78   1e-13
UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including glyo...    78   2e-13
UniRef50_A6L4P4 Cluster: Putative metallo-beta-lactamase; n=2; B...    78   2e-13
UniRef50_Q1PVC6 Cluster: Similar to hydroxyacylglutathione hydro...    77   2e-13
UniRef50_A3SZ22 Cluster: Beta-lactamase-like; n=6; Proteobacteri...    77   2e-13
UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1; Syn...    77   4e-13
UniRef50_A1VR45 Cluster: Beta-lactamase domain protein; n=1; Pol...    75   1e-12
UniRef50_A6L981 Cluster: Metallo-beta-lactamase family protein; ...    75   1e-12
UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein; ...    74   3e-12
UniRef50_A4AWZ7 Cluster: Putative uncharacterized protein; n=2; ...    73   4e-12
UniRef50_Q57544 Cluster: Uncharacterized protein HI1663; n=20; P...    73   4e-12
UniRef50_Q314Q9 Cluster: Metallo-beta-lactamase family protein; ...    73   5e-12
UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3; Cy...    73   5e-12
UniRef50_A6EK80 Cluster: Metallo-beta-lactamase family protein; ...    73   5e-12
UniRef50_A4C5I4 Cluster: Beta-lactamase-like protein; n=1; Pseud...    73   5e-12
UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Re...    73   7e-12
UniRef50_A3IFE3 Cluster: YqgX; n=1; Bacillus sp. B14905|Rep: Yqg...    73   7e-12
UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of met...    72   9e-12
UniRef50_A3ZW37 Cluster: Putative uncharacterized protein; n=1; ...    72   9e-12
UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2; Bac...    72   1e-11
UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein; ...    71   2e-11
UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3; ...    71   2e-11
UniRef50_Q0W1G4 Cluster: Putative metallo-beta-lactamase; n=1; u...    71   2e-11
UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10; Bac...    71   2e-11
UniRef50_Q9JXH3 Cluster: Glyoxalase II family protein; n=5; Prot...    71   3e-11
UniRef50_Q39KM6 Cluster: Beta-lactamase-like; n=36; Proteobacter...    70   4e-11
UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1; Clost...    70   4e-11
UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1; Vic...    69   6e-11
UniRef50_Q54EJ5 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    69   6e-11
UniRef50_A1ID45 Cluster: Beta-lactamase-like; n=3; Bacteria|Rep:...    69   9e-11
UniRef50_Q39ZZ6 Cluster: Metallo-beta-lactamase family protein; ...    69   1e-10
UniRef50_A5FR77 Cluster: Beta-lactamase domain protein; n=3; Deh...    69   1e-10
UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium c...    69   1e-10
UniRef50_Q9PFB0 Cluster: Beta-lactamase hydrolase-like protein; ...    69   1e-10
UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putat...    68   1e-10
UniRef50_Q8EQ13 Cluster: Hypothetical conserved protein; n=1; Oc...    68   1e-10
UniRef50_Q81LX4 Cluster: Metallo-beta-lactamase family protein; ...    68   1e-10
UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1; Pseudoalterom...    68   1e-10
UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lenti...    68   1e-10
UniRef50_Q1AWY9 Cluster: Beta-lactamase-like protein; n=1; Rubro...    68   2e-10
UniRef50_Q11FA6 Cluster: Beta-lactamase-like; n=121; Proteobacte...    68   2e-10
UniRef50_A6PMC1 Cluster: Beta-lactamase domain protein; n=1; Vic...    68   2e-10
UniRef50_A2FLV6 Cluster: Metallo-beta-lactamase superfamily prot...    68   2e-10
UniRef50_Q1MQL8 Cluster: Zn-dependent hydrolases, including glyo...    67   3e-10
UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1; ...    67   3e-10
UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: ...    67   3e-10
UniRef50_Q5XD24 Cluster: Uncharacterized protein M6_Spy0554; n=4...    67   3e-10
UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1; ...    67   3e-10
UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase fam...    66   6e-10
UniRef50_Q3A304 Cluster: Putative uncharacterized protein; n=1; ...    66   6e-10
UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Re...    66   6e-10
UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1; ...    66   6e-10
UniRef50_A3I369 Cluster: Metallo-beta-lactamase family protein; ...    66   6e-10
UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21; Ac...    66   6e-10
UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5; ...    66   6e-10
UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2; Clo...    66   8e-10
UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1; Alk...    66   8e-10
UniRef50_A0Z233 Cluster: Putative uncharacterized protein; n=3; ...    65   1e-09
UniRef50_A0HF94 Cluster: Beta-lactamase-like; n=6; cellular orga...    65   1e-09
UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putat...    65   1e-09
UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putat...    65   1e-09
UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658;...    65   1e-09
UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleos...    64   2e-09
UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Re...    64   2e-09
UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    64   2e-09
UniRef50_A7HGC5 Cluster: Beta-lactamase domain protein; n=2; Ana...    64   2e-09
UniRef50_A2DJY1 Cluster: Metallo-beta-lactamase superfamily prot...    64   2e-09
UniRef50_Q41FV9 Cluster: Beta-lactamase-like; n=1; Exiguobacteri...    64   3e-09
UniRef50_A7IG57 Cluster: Beta-lactamase domain protein; n=1; Xan...    64   3e-09
UniRef50_A7CUG8 Cluster: Beta-lactamase domain protein; n=1; Opi...    63   4e-09
UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2; ...    63   4e-09
UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    63   6e-09
UniRef50_Q47LT8 Cluster: Putative hydrolase; n=1; Thermobifida f...    63   6e-09
UniRef50_Q5FRS6 Cluster: Metallo-beta-lactamase superfamily prot...    62   7e-09
UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium di...    62   7e-09
UniRef50_A4XI82 Cluster: Beta-lactamase domain protein; n=1; Cal...    62   7e-09
UniRef50_A1ZPC4 Cluster: Metallo-beta-lactamase family protein; ...    62   7e-09
UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n...    62   1e-08
UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrola...    62   1e-08
UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomy...    62   1e-08
UniRef50_Q7R4U1 Cluster: GLP_440_31929_31255; n=1; Giardia lambl...    61   2e-08
UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    61   2e-08
UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; ...    61   2e-08
UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    61   2e-08
UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    61   2e-08
UniRef50_Q3IR18 Cluster: Homolog 4 to thiosulfate sulfurtransfer...    61   2e-08
UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;...    61   2e-08
UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=1...    60   3e-08
UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrola...    60   4e-08
UniRef50_Q2S0T9 Cluster: Metallo-beta-lactamase family protein; ...    60   4e-08
UniRef50_A2DXP6 Cluster: Metallo-beta-lactamase superfamily prot...    60   4e-08
UniRef50_Q2SAD4 Cluster: Zn-dependent Hydrolase, including glyox...    60   5e-08
UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putat...    60   5e-08
UniRef50_Q1IW29 Cluster: Beta-lactamase-like protein; n=4; Deino...    59   7e-08
UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1; Roseo...    59   7e-08
UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; ...    59   7e-08
UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;...    59   7e-08
UniRef50_O67893 Cluster: Uncharacterized protein aq_2135; n=1; A...    59   7e-08
UniRef50_A3CXZ9 Cluster: Beta-lactamase domain protein; n=1; Met...    59   9e-08
UniRef50_Q9HQ50 Cluster: Flavoprotein; n=4; Halobacteriaceae|Rep...    58   1e-07
UniRef50_UPI000049880A Cluster: metallo-beta-lactamase superfami...    58   2e-07
UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1; ...    58   2e-07
UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: G...    58   2e-07
UniRef50_Q5HP04 Cluster: Metallo-beta-lactamase family protein; ...    58   2e-07
UniRef50_P75849 Cluster: Uncharacterized protein ycbL; n=120; Ba...    58   2e-07
UniRef50_Q1D198 Cluster: Metallo-beta-lactamase family protein; ...    57   3e-07
UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,...    54   4e-07
UniRef50_Q9A911 Cluster: Glyoxalase II family protein; n=21; Pro...    57   4e-07
UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri...    57   4e-07
UniRef50_Q73JL5 Cluster: Metallo-beta-lactamase family protein; ...    57   4e-07
UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyox...    57   4e-07
UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9; ...    57   4e-07
UniRef50_A5WCY4 Cluster: Beta-lactamase domain protein; n=5; Pro...    57   4e-07
UniRef50_A3HIG2 Cluster: Beta-lactamase domain protein; n=18; Ga...    57   4e-07
UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    56   5e-07
UniRef50_Q8Y5A2 Cluster: Lmo2167 protein; n=12; Listeria|Rep: Lm...    56   6e-07
UniRef50_Q5H3M1 Cluster: Beta-lactamase; n=8; Xanthomonadaceae|R...    56   6e-07
UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geo...    56   6e-07
UniRef50_A1AVZ9 Cluster: Beta-lactamase domain protein; n=2; sul...    56   6e-07
UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Gl...    56   6e-07
UniRef50_UPI00006CD179 Cluster: metallo-beta-lactamase superfami...    56   9e-07
UniRef50_Q1PVA8 Cluster: Similar to hydroxyacylglutathione hydro...    56   9e-07
UniRef50_A0LDZ9 Cluster: Beta-lactamase domain protein; n=1; Mag...    56   9e-07
UniRef50_A2FNK4 Cluster: Metallo-beta-lactamase superfamily prot...    56   9e-07
UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase relate...    56   9e-07
UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular o...    56   9e-07
UniRef50_A0B5Y5 Cluster: Beta-lactamase domain protein; n=1; Met...    56   9e-07
UniRef50_Q2LX15 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    55   1e-06
UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putat...    55   1e-06
UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrola...    55   1e-06
UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mit...    55   1e-06
UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1; ...    55   1e-06
UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precur...    55   1e-06
UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    55   1e-06
UniRef50_Q01Q87 Cluster: Beta-lactamase domain protein; n=1; Sol...    55   1e-06
UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1; ...    55   1e-06
UniRef50_Q8ZX02 Cluster: Conserved protein; n=4; Pyrobaculum|Rep...    55   1e-06
UniRef50_A3VUN8 Cluster: Hydrolase; n=5; Proteobacteria|Rep: Hyd...    54   2e-06
UniRef50_A0M126 Cluster: Metallo-beta-lactamase/rhodanese-like d...    54   2e-06
UniRef50_Q22PH1 Cluster: Metallo-beta-lactamase superfamily prot...    54   2e-06
UniRef50_O54661 Cluster: Putative uncharacterized protein; n=1; ...    54   2e-06
UniRef50_Q8NQ06 Cluster: Zn-dependent hydrolases, including glyo...    54   3e-06
UniRef50_Q8D376 Cluster: YcbL protein; n=1; Wigglesworthia gloss...    54   3e-06
UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytopl...    54   3e-06
UniRef50_A0R0C8 Cluster: Metallo-beta-lactamase family protein; ...    54   3e-06
UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3; Methanosar...    54   3e-06
UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; ...    54   3e-06
UniRef50_A4IPS9 Cluster: Metallo-beta-lactamase family protein; ...    54   3e-06
UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrola...    54   3e-06
UniRef50_Q22YX3 Cluster: Metallo-beta-lactamase superfamily prot...    54   3e-06
UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Eu...    54   3e-06
UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putat...    54   3e-06
UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase...    53   5e-06
UniRef50_A0DS29 Cluster: Chromosome undetermined scaffold_61, wh...    53   5e-06
UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;...    53   5e-06
UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrill...    53   6e-06
UniRef50_Q4JWL1 Cluster: Putative uncharacterized protein; n=1; ...    53   6e-06
UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    53   6e-06
UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; ...    53   6e-06
UniRef50_A4E7W3 Cluster: Putative uncharacterized protein; n=1; ...    53   6e-06
UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000...    52   8e-06
UniRef50_Q8REE5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    52   8e-06
UniRef50_Q89VZ3 Cluster: Bll0900 protein; n=9; Rhizobiales|Rep: ...    52   1e-05
UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    52   1e-05
UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira...    52   1e-05
UniRef50_Q9YCJ7 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4; Hal...    52   1e-05
UniRef50_Q2LSA2 Cluster: Zn-dependent hydrolases; n=1; Syntrophu...    52   1e-05
UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    52   1e-05
UniRef50_A4W8U6 Cluster: Beta-lactamase domain protein; n=11; Ga...    52   1e-05
UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_Q4JCD2 Cluster: Conserved protein; n=1; Sulfolobus acid...    52   1e-05
UniRef50_Q488C8 Cluster: Aminotransferase, class V; n=5; Alterom...    51   2e-05
UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1; Clo...    51   2e-05
UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    51   2e-05
UniRef50_Q4QBB0 Cluster: Metallo-beta-lactamase family protein-l...    51   2e-05
UniRef50_A5V0A4 Cluster: Beta-lactamase domain protein; n=2; Ros...    51   2e-05
UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella ve...    51   2e-05
UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily prot...    50   3e-05
UniRef50_Q3WFW5 Cluster: Beta-lactamase-like; n=1; Frankia sp. E...    50   3e-05
UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    50   3e-05
UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein; ...    50   3e-05
UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep...    50   3e-05
UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrola...    50   4e-05
UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    50   4e-05
UniRef50_A0NAW9 Cluster: ENSANGP00000031703; n=1; Anopheles gamb...    50   4e-05
UniRef50_Q6MFA0 Cluster: Putative uncharacterized protein; n=1; ...    50   6e-05
UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter...    50   6e-05
UniRef50_A4IWV0 Cluster: Metallo-beta-lactamase superfamily prot...    50   6e-05
UniRef50_A3Q4D8 Cluster: Beta-lactamase domain protein; n=8; Act...    50   6e-05
UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrola...    50   6e-05
UniRef50_A0LJP1 Cluster: Beta-lactamase domain protein; n=1; Syn...    50   6e-05
UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1; Syn...    50   6e-05
UniRef50_Q7VR07 Cluster: Zn-dependent hydrolase; n=7; Gammaprote...    49   7e-05
UniRef50_Q1Q513 Cluster: Putative uncharacterized protein; n=1; ...    49   7e-05
UniRef50_Q0RV10 Cluster: Possible hydroxyacylglutathione hydrola...    49   7e-05
UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    49   7e-05
UniRef50_A1RAH8 Cluster: Metallo-beta-lactamase superfamily prot...    49   7e-05
UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    48   8e-05
UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7; Bac...    49   1e-04
UniRef50_Q0LHZ1 Cluster: Beta-lactamase-like; n=1; Herpetosiphon...    49   1e-04
UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putat...    49   1e-04
UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrola...    49   1e-04
UniRef50_Q5HUY3 Cluster: Metallo-beta-lactamase family protein; ...    48   1e-04
UniRef50_A1SJB6 Cluster: Beta-lactamase domain protein; n=13; Ac...    48   1e-04
UniRef50_Q0W7P0 Cluster: Putative uncharacterized protein; n=1; ...    48   1e-04
UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrola...    48   1e-04
UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrola...    48   2e-04
UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    48   2e-04
UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium c...    48   2e-04
UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, who...    48   2e-04
UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q2H306 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    48   2e-04
UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathion...    48   2e-04
UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrola...    48   2e-04
UniRef50_A4AQV7 Cluster: Metallo-beta-lactamase superfamily prot...    48   2e-04
UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precur...    48   2e-04
UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    48   2e-04
UniRef50_Q7QZA0 Cluster: GLP_567_43928_43275; n=1; Giardia lambl...    48   2e-04
UniRef50_Q89AN4 Cluster: Probable hydroxyacylglutathione hydrola...    48   2e-04
UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein; ...    47   3e-04
UniRef50_Q0RV06 Cluster: Possible hydrolase; n=11; Actinomycetal...    47   3e-04
UniRef50_Q031I9 Cluster: Zn-dependent hydrolase, including glyox...    47   3e-04
UniRef50_A3I4E3 Cluster: Possible Zn-dependent hydrolase, beta-l...    47   3e-04
UniRef50_A4YDP4 Cluster: Beta-lactamase domain protein; n=1; Met...    47   3e-04
UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily prot...    47   4e-04
UniRef50_Q2W813 Cluster: Zn-dependent hydrolase; n=3; Magnetospi...    47   4e-04
UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including glyox...    47   4e-04
UniRef50_A6NSY9 Cluster: Putative uncharacterized protein; n=1; ...    47   4e-04
UniRef50_A0WBI6 Cluster: Beta-lactamase-like; n=1; Geobacter lov...    47   4e-04
UniRef50_A0JR39 Cluster: Beta-lactamase domain protein; n=11; Ac...    47   4e-04
UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1; ...    47   4e-04
UniRef50_O29680 Cluster: Putative uncharacterized protein; n=1; ...    47   4e-04
UniRef50_P96981 Cluster: Probable hydroxyacylglutathione hydrola...    47   4e-04
UniRef50_UPI000050F771 Cluster: COG0491: Zn-dependent hydrolases...    46   5e-04
UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase, putat...    46   5e-04
UniRef50_Q4JW14 Cluster: Putative uncharacterized protein; n=1; ...    46   5e-04
UniRef50_Q3IKH5 Cluster: Putative enzyme of the cysteine desulfu...    46   5e-04
UniRef50_Q1LZ83 Cluster: Similar to lactamase, beta 2; n=2; Bos ...    46   5e-04
UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily prot...    46   5e-04
UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1; ...    46   5e-04
UniRef50_Q2S5Q9 Cluster: Metallo-beta-lactamase superfamily prot...    46   7e-04
UniRef50_A5FZE9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    46   7e-04
UniRef50_A1R963 Cluster: Metallo-beta-lactamase superfamily prot...    46   7e-04
UniRef50_A4FI79 Cluster: Metallo-beta-lactamase; n=3; Actinomyce...    46   0.001
UniRef50_A5YSG8 Cluster: Thiosulfate sulfurtransferase/hydrolase...    46   0.001
UniRef50_A0Z1L0 Cluster: NUDIX hydrolase:Beta-lactamase-like pro...    45   0.001
UniRef50_Q8TUW9 Cluster: Zn-dependent hydrolase; n=1; Methanopyr...    45   0.001
UniRef50_A2SPW9 Cluster: Beta-lactamase domain protein; n=1; Met...    45   0.001
UniRef50_A7D422 Cluster: Beta-lactamase domain protein; n=2; Hal...    37   0.002
UniRef50_Q6A9K5 Cluster: Zn-dependent hydrolase; n=1; Propioniba...    45   0.002
UniRef50_Q0RV20 Cluster: Possible hydrolase; n=1; Rhodococcus sp...    45   0.002
UniRef50_A6CFG1 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_A5UWV7 Cluster: Beta-lactamase domain protein; n=2; Ros...    45   0.002
UniRef50_A0K1H6 Cluster: Beta-lactamase domain protein; n=5; Act...    45   0.002
UniRef50_A0H241 Cluster: Beta-lactamase-like; n=2; Chloroflexus|...    45   0.002
UniRef50_Q9Y392 Cluster: CGI-83 protein; n=24; Coelomata|Rep: CG...    45   0.002
UniRef50_A3CRI7 Cluster: Beta-lactamase domain protein; n=3; Met...    45   0.002
UniRef50_Q1AUZ4 Cluster: Beta-lactamase-like protein; n=1; Rubro...    44   0.002
UniRef50_Q0HI83 Cluster: Hydroxyacylglutathione hydrolase; n=5; ...    44   0.002
UniRef50_Q2JD17 Cluster: Beta-lactamase-like; n=37; Actinomyceta...    44   0.003
UniRef50_P71374 Cluster: Probable hydroxyacylglutathione hydrola...    44   0.003
UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep...    44   0.004
UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas...    44   0.004
UniRef50_Q1AVJ8 Cluster: Beta-lactamase-like protein; n=4; Bacte...    44   0.004
UniRef50_O30264 Cluster: Putative uncharacterized protein; n=1; ...    44   0.004
UniRef50_UPI0000E87C10 Cluster: putative hydroxyacylglutathione ...    43   0.005
UniRef50_UPI0000499269 Cluster: metallo-beta-lactamase superfami...    43   0.005
UniRef50_Q0VPW4 Cluster: Metallo-beta-lactamase family protein; ...    43   0.005
UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein; ...    43   0.005
UniRef50_Q2FPN8 Cluster: Beta-lactamase-like; n=1; Methanospiril...    43   0.005
UniRef50_Q8NU87 Cluster: Zn-dependent hydrolases, including glyo...    43   0.006
UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily prot...    43   0.006
UniRef50_A6F4F3 Cluster: Zn-dependent hydrolase or glyoxylase,me...    43   0.006
UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB; ...    43   0.006
UniRef50_A4G3L0 Cluster: Putative uncharacterized protein; n=1; ...    43   0.006
UniRef50_Q2UI96 Cluster: Zn-dependent hydrolases; n=4; Pezizomyc...    43   0.006
UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein; ...    42   0.008
UniRef50_A2QJI7 Cluster: Catalytic activity:; n=3; Aspergillus|R...    42   0.008
UniRef50_UPI00015978D7 Cluster: NrsD; n=1; Bacillus amyloliquefa...    42   0.011
UniRef50_UPI0000ECBE0D Cluster: ETHE1 protein, mitochondrial pre...    42   0.011
UniRef50_Q8F1D2 Cluster: Metallo-beta-lactamase superfamily prot...    42   0.011
UniRef50_Q01D52 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo...    42   0.011
UniRef50_Q9PBI4 Cluster: Hydroxyacylglutathione hydrolase; n=9; ...    42   0.015
UniRef50_Q0G0G6 Cluster: Metallo-beta-lactamase family protein; ...    42   0.015
UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily prot...    42   0.015
UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo...    42   0.015
UniRef50_Q2J8G9 Cluster: Beta-lactamase-like; n=4; Frankia|Rep: ...    41   0.020
UniRef50_Q5UF41 Cluster: Predicted metallo-beta-lactamase family...    41   0.020
UniRef50_O28526 Cluster: Putative uncharacterized protein; n=1; ...    41   0.020
UniRef50_Q7VIV4 Cluster: Predicted hydrolase; n=4; Epsilonproteo...    41   0.026
UniRef50_Q4JVE7 Cluster: Putative uncharacterized protein; n=1; ...    41   0.026
UniRef50_Q2JCI6 Cluster: Beta-lactamase-like; n=33; Actinomyceta...    41   0.026
UniRef50_Q2LXM2 Cluster: Zn-dependent hydrolases, including glyo...    40   0.034
UniRef50_Q21J46 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    40   0.034
UniRef50_A7A5I2 Cluster: Putative uncharacterized protein; n=1; ...    40   0.034
UniRef50_UPI00006CA6B9 Cluster: Rhodanese-like domain containing...    40   0.045
UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein; ...    40   0.045
UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily hydr...    40   0.045
UniRef50_Q749H4 Cluster: Metallo-beta-lactamase family protein; ...    40   0.045
UniRef50_Q01RD2 Cluster: Beta-lactamase precursor; n=1; Solibact...    40   0.045
UniRef50_A7CQ32 Cluster: Beta-lactamase domain protein; n=1; Opi...    40   0.045
UniRef50_A5USF6 Cluster: Beta-lactamase domain protein; n=3; Bac...    40   0.045
UniRef50_A1R7K8 Cluster: Metallo-beta-lactamase superfamily prot...    40   0.045
UniRef50_Q8D3D4 Cluster: GloB protein; n=1; Wigglesworthia gloss...    40   0.060
UniRef50_Q6NAT5 Cluster: Beta-lactamase-like; n=35; Alphaproteob...    40   0.060
UniRef50_Q0RIQ0 Cluster: Putative uncharacterized protein; n=1; ...    40   0.060
UniRef50_A0RPV5 Cluster: Metallo-beta-lactamase family protein; ...    40   0.060
UniRef50_Q9Y8P8 Cluster: Putative uncharacterized protein; n=1; ...    40   0.060
UniRef50_Q9HS22 Cluster: Putative uncharacterized protein; n=1; ...    40   0.060
UniRef50_Q5V0M3 Cluster: Putative uncharacterized protein; n=1; ...    40   0.060
UniRef50_O69645 Cluster: POSSIBLE HYDROLASE; n=30; Bacteria|Rep:...    39   0.079
UniRef50_A6BZ99 Cluster: Putative uncharacterized protein; n=2; ...    39   0.079
UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase precur...    39   0.079
UniRef50_Q1E6T3 Cluster: Putative uncharacterized protein; n=1; ...    39   0.079
UniRef50_Q9A9Q1 Cluster: Metallo-beta-lactamase family protein; ...    39   0.10 
UniRef50_Q7MQ55 Cluster: Putative hydroxyacylglutathione hydrola...    39   0.10 
UniRef50_Q6A8J8 Cluster: Metallo-beta-lactamase superfamily prot...    39   0.10 
UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    39   0.10 
UniRef50_A3IH33 Cluster: Hydrolase; n=1; Cyanothece sp. CCY 0110...    39   0.10 
UniRef50_Q4D0L0 Cluster: Metallo-beta-lactamase-like protein, pu...    39   0.10 
UniRef50_Q8THA3 Cluster: Metallo-beta-lactamase; n=5; Archaea|Re...    38   0.14 
UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1; ...    38   0.18 
UniRef50_Q9YFB1 Cluster: Putative uncharacterized protein; n=1; ...    38   0.18 
UniRef50_UPI000050FB28 Cluster: COG0491: Zn-dependent hydrolases...    38   0.24 
UniRef50_Q5YXI3 Cluster: Putative uncharacterized protein; n=3; ...    38   0.24 
UniRef50_Q1N198 Cluster: Probable hydroxyacylglutathione hydrola...    38   0.24 
UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    38   0.24 
UniRef50_A6LG49 Cluster: Putative uncharacterized protein; n=1; ...    38   0.24 
UniRef50_A0LWF9 Cluster: Beta-lactamase domain protein; n=1; Aci...    38   0.24 
UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase, putat...    38   0.24 
UniRef50_Q24F45 Cluster: Hydroxyacylglutathione hydrolase, putat...    38   0.24 
UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase, mitoc...    38   0.24 
UniRef50_Q0SG22 Cluster: Beta lactamase; n=1; Rhodococcus sp. RH...    37   0.32 
UniRef50_Q0I8S8 Cluster: Metallo-beta-lactamase superfamily hydr...    37   0.32 
UniRef50_A4YQA8 Cluster: Putative beta-lactamase; n=1; Bradyrhiz...    37   0.32 
UniRef50_Q4WQZ6 Cluster: Metallo-beta-lactamase domain protein, ...    37   0.32 
UniRef50_UPI000023EAC6 Cluster: hypothetical protein FG07959.1; ...    37   0.42 
UniRef50_Q5UAZ9 Cluster: Hypothetical hydroxylase protein; n=1; ...    37   0.42 
UniRef50_Q1VZM6 Cluster: Metallo-beta-lactamase superfamily prot...    37   0.42 
UniRef50_A5INW0 Cluster: Beta-lactamase domain protein; n=30; St...    37   0.42 
UniRef50_A4BRT9 Cluster: Smc1; n=1; Nitrococcus mobilis Nb-231|R...    37   0.42 
UniRef50_A3VRC1 Cluster: Metallo-beta-lactamase family protein; ...    37   0.42 
UniRef50_A5PJT0 Cluster: MGC152119 protein; n=17; Euteleostomi|R...    37   0.42 
UniRef50_A7RLT0 Cluster: Predicted protein; n=1; Nematostella ve...    37   0.42 
UniRef50_O29716 Cluster: Putative uncharacterized protein; n=1; ...    37   0.42 
UniRef50_UPI000050FD95 Cluster: COG0491: Zn-dependent hydrolases...    36   0.56 
UniRef50_Q8EN25 Cluster: Hypothetical conserved protein; n=1; Oc...    36   0.56 
UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrola...    36   0.56 
UniRef50_Q0AY27 Cluster: Putative uncharacterized protein; n=1; ...    36   0.56 
UniRef50_A7HBH3 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    36   0.56 
UniRef50_A4ALM0 Cluster: Putative hydrolase; n=1; marine actinob...    36   0.56 
UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2; Bac...    36   0.56 
UniRef50_A2WKC0 Cluster: Putative uncharacterized protein; n=4; ...    36   0.56 
UniRef50_Q4W945 Cluster: Metallo-beta-lactamase domain protein; ...    36   0.56 
UniRef50_Q0RHX0 Cluster: Putative uncharacterized protein; n=1; ...    36   0.74 
UniRef50_A5URH7 Cluster: Beta-lactamase domain protein; n=4; Chl...    36   0.74 
UniRef50_A5PEY5 Cluster: Putative uncharacterized protein; n=3; ...    36   0.74 
UniRef50_Q2FPN7 Cluster: Beta-lactamase-like; n=1; Methanospiril...    36   0.74 
UniRef50_A7I7Q8 Cluster: Beta-lactamase domain protein; n=1; Can...    36   0.74 
UniRef50_Q46TQ6 Cluster: Beta-lactamase-like; n=1; Ralstonia eut...    36   0.97 
UniRef50_Q0AZS8 Cluster: Putative uncharacterized protein; n=1; ...    36   0.97 
UniRef50_A1WXD9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    36   0.97 
UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily prot...    36   0.97 
UniRef50_O27335 Cluster: Conserved protein; n=2; Methanobacteria...    36   0.97 
UniRef50_Q895R7 Cluster: Putative uncharacterized protein; n=2; ...    35   1.3  
UniRef50_Q82N31 Cluster: Putative metallo-beta-lactamase-like pr...    35   1.3  
UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2...    35   1.3  
UniRef50_Q2U887 Cluster: Glyoxylase; n=2; Trichocomaceae|Rep: Gl...    35   1.3  
UniRef50_A7I6D7 Cluster: Beta-lactamase domain protein; n=1; Can...    35   1.7  
UniRef50_UPI00006CD0F1 Cluster: hypothetical protein TTHERM_0012...    34   2.3  
UniRef50_UPI00003C0664 Cluster: PREDICTED: similar to CG12375-PA...    34   2.3  
UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    34   2.3  
UniRef50_Q2G7J0 Cluster: Beta-lactamase-like protein precursor; ...    34   2.3  
UniRef50_Q9K578 Cluster: FEZ-1 protein; n=1; Fluoribacter gorman...    34   2.3  
UniRef50_Q1IJS0 Cluster: Beta-lactamase-like precursor; n=1; Aci...    34   2.3  
UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon...    34   2.3  
UniRef50_A7RLS8 Cluster: Predicted protein; n=3; Nematostella ve...    34   2.3  
UniRef50_Q18FM0 Cluster: Hydrolase; n=4; Halobacteriaceae|Rep: H...    34   2.3  
UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome sh...    34   3.0  
UniRef50_Q8RE48 Cluster: Zinc metallohydrolase, glyoxalase II fa...    34   3.0  
UniRef50_Q7UGS7 Cluster: Putative uncharacterized protein; n=3; ...    34   3.0  
UniRef50_Q73QI1 Cluster: Metallo-beta-lactamase family protein; ...    34   3.0  
UniRef50_Q6D395 Cluster: Metallo-beta-lactamase; n=1; Pectobacte...    34   3.0  
UniRef50_Q18SX3 Cluster: Beta-lactamase-like; n=2; Desulfitobact...    34   3.0  
UniRef50_Q0RVM2 Cluster: Putative uncharacterized protein; n=1; ...    34   3.0  
UniRef50_Q02BY2 Cluster: Putative uncharacterized protein precur...    34   3.0  
UniRef50_A1WC27 Cluster: Beta-lactamase domain protein; n=9; cel...    34   3.0  
UniRef50_UPI0000EB2486 Cluster: Uncharacterized protein C9orf140...    33   3.9  
UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;...    33   3.9  
UniRef50_Q1IPB4 Cluster: Beta-lactamase-like precursor; n=1; Aci...    33   3.9  
UniRef50_A6GHH4 Cluster: Beta-lactamase-like protein; n=1; Plesi...    33   3.9  
UniRef50_A5V998 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    33   3.9  
UniRef50_A5P820 Cluster: Beta-lactamase-like protein; n=1; Eryth...    33   3.9  
UniRef50_A3JY79 Cluster: Metallo-beta-lactamase; n=1; Sagittula ...    33   3.9  
UniRef50_Q10PC8 Cluster: Hydroxyproline-rich glycoprotein family...    33   3.9  
UniRef50_A3AFX3 Cluster: Putative uncharacterized protein; n=1; ...    33   3.9  
UniRef50_Q4Q4V2 Cluster: Putative uncharacterized protein; n=3; ...    33   3.9  
UniRef50_UPI00005A28D5 Cluster: PREDICTED: hypothetical protein ...    33   5.2  
UniRef50_Q8Y6A5 Cluster: Lmo1790 protein; n=11; Listeria|Rep: Lm...    33   5.2  
UniRef50_Q47TR0 Cluster: Putative hydrolase; n=1; Thermobifida f...    33   5.2  
UniRef50_Q1GRV6 Cluster: Beta-lactamase-like protein; n=1; Sphin...    33   5.2  
UniRef50_Q08X15 Cluster: Putative uncharacterized protein; n=1; ...    33   5.2  
UniRef50_A5IMS0 Cluster: Beta-lactamase domain protein; n=2; The...    33   5.2  
UniRef50_Q7QXR8 Cluster: GLP_399_8255_9553; n=1; Giardia lamblia...    33   5.2  
UniRef50_Q4QCE8 Cluster: Metallo-beta-lactamase family-like prot...    33   5.2  
UniRef50_A1CDF5 Cluster: NF-X1 finger transcription factor, puta...    33   5.2  
UniRef50_Q8ZT88 Cluster: Beta-lactamase-like protein; n=4; Pyrob...    33   5.2  
UniRef50_Q18JI1 Cluster: Metallo-beta-lactamase family protein /...    33   5.2  
UniRef50_Q5SIE5 Cluster: Metallo-beta-lactamase family protein; ...    33   6.9  
UniRef50_Q1LMU9 Cluster: Beta-lactamase-like protein; n=3; Cupri...    33   6.9  
UniRef50_Q09CU6 Cluster: Metallo-beta-lactamase family protein; ...    33   6.9  
UniRef50_A6CMS1 Cluster: Metallo-beta-lactamase family protein; ...    33   6.9  
UniRef50_Q5CWB4 Cluster: VPS13 like protein involved in vacuolar...    33   6.9  
UniRef50_Q29LU5 Cluster: GA13545-PA; n=1; Drosophila pseudoobscu...    33   6.9  
UniRef50_A5K1D4 Cluster: Putative uncharacterized protein; n=1; ...    33   6.9  
UniRef50_A2DNB4 Cluster: Putative uncharacterized protein; n=5; ...    33   6.9  
UniRef50_A1CUD3 Cluster: Metallo-beta-lactamase domain protein, ...    33   6.9  
UniRef50_Q89GW5 Cluster: Blr6230 protein; n=4; Bradyrhizobium|Re...    32   9.1  
UniRef50_Q72KR0 Cluster: Metallo-beta-lactamase protein; n=2; Th...    32   9.1  
UniRef50_Q47SL7 Cluster: Similar to Zn-dependent hydrolases incl...    32   9.1  
UniRef50_Q3A9D5 Cluster: Metallo-beta-lactamase family protein; ...    32   9.1  
UniRef50_Q2RLT5 Cluster: Beta-lactamase-like; n=1; Moorella ther...    32   9.1  
UniRef50_A5VFI5 Cluster: Beta-lactamase domain protein; n=2; Sph...    32   9.1  
UniRef50_A1SDT5 Cluster: Beta-lactamase domain protein; n=2; Act...    32   9.1  

>UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular
           organisms|Rep: ENSANGP00000000940 - Anopheles gambiae
           str. PEST
          Length = 248

 Score =  233 bits (571), Expect = 2e-60
 Identities = 103/151 (68%), Positives = 126/151 (83%)
 Frame = +2

Query: 134 GKLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS 313
           G LK L+PGT SVI + SGA+AD HL+D + V+FG HEL A +TPGHTNGC+T++  EQ 
Sbjct: 81  GFLKQLLPGTVSVISQSSGAKADKHLVDNETVQFGRHELRAMSTPGHTNGCMTFLVEEQG 140

Query: 314 LAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEE 493
           +AFTGDTLLIRGCGRTDFQEG+S +LY+SVH RIFTLP+ + L+PAHDY+G   T+VAEE
Sbjct: 141 IAFTGDTLLIRGCGRTDFQEGDSRSLYRSVHERIFTLPENFRLFPAHDYKGNMETTVAEE 200

Query: 494 KKYNPRLTKSLAEFVEIMDNLNLPYPKMINK 586
           K+YNPRLTK +  FVE+M+NLNLPYPKMI K
Sbjct: 201 KRYNPRLTKDVEAFVELMNNLNLPYPKMIGK 231


>UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 279

 Score =  207 bits (505), Expect = 2e-52
 Identities = 94/149 (63%), Positives = 117/149 (78%)
 Frame = +2

Query: 134 GKLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS 313
           G L+ L  G +SVI   SGA+AD HL +GD + FG+H + A ATPGHTNGC+TY+  +Q 
Sbjct: 114 GWLRKLT-GCQSVIAAASGAKADRHLNEGDRIDFGTHVIDALATPGHTNGCMTYVIKDQG 172

Query: 314 LAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEE 493
             FTGDTLLIRGCGRTDFQEG    LY++VH++IFTLP+ + +YPAHDY+GQ  +SV EE
Sbjct: 173 CVFTGDTLLIRGCGRTDFQEGCPRNLYENVHSKIFTLPENFRIYPAHDYKGQMESSVWEE 232

Query: 494 KKYNPRLTKSLAEFVEIMDNLNLPYPKMI 580
           K+YNPRLTK + EFV+IM+NLNLPYPK I
Sbjct: 233 KRYNPRLTKDIEEFVKIMENLNLPYPKKI 261


>UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor;
           n=36; cellular organisms|Rep: ETHE1 protein,
           mitochondrial precursor - Homo sapiens (Human)
          Length = 254

 Score =  200 bits (489), Expect = 2e-50
 Identities = 91/152 (59%), Positives = 118/152 (77%)
 Frame = +2

Query: 134 GKLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS 313
           G L+SL+PG +SVI + SGAQAD+H+ DGD +RFG   L   A+PGHT GC+T++ ++ S
Sbjct: 89  GLLRSLLPGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVLNDHS 148

Query: 314 LAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEE 493
           +AFTGD LLIRGCGRTDFQ+G ++TLY SVH +IFTLP + ++YPAHDY G T ++V EE
Sbjct: 149 MAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEE 208

Query: 494 KKYNPRLTKSLAEFVEIMDNLNLPYPKMINKA 589
           +  NPRLT S  EFV+IM NLNLP P+ I+ A
Sbjct: 209 RTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA 240


>UniRef50_Q39B63 Cluster: Beta-lactamase-like; n=16;
           Proteobacteria|Rep: Beta-lactamase-like - Burkholderia
           sp. (strain 383) (Burkholderia cepacia (strain ATCC
           17760/ NCIB 9086 / R18194))
          Length = 356

 Score =  162 bits (393), Expect = 7e-39
 Identities = 79/147 (53%), Positives = 102/147 (69%), Gaps = 3/147 (2%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334
           G+   I   SGAQ AD +L DGD   FG+  L   ATPGHT+GC++ +  ++S+AFTGD 
Sbjct: 74  GSTIAISAASGAQGADRYLNDGDRCAFGARYLTVRATPGHTSGCISLVLDDESMAFTGDC 133

Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           LLIRG GRTDFQ+G+   LY++VH R+FTLP   +LYPAHDYRG T TSV EE+++NPRL
Sbjct: 134 LLIRGTGRTDFQQGDPRALYRAVHGRLFTLPAACLLYPAHDYRGLTVTSVGEERRFNPRL 193

Query: 515 TKSLAE--FVEIMDNLNLPYPKMINKA 589
              L+E  F   M NL L +P+ I+ A
Sbjct: 194 GGDLSEDDFAGYMRNLGLAHPRQIDVA 220


>UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1;
           Acinetobacter baumannii ATCC 17978|Rep:
           Beta-lactamase-like protein - Acinetobacter baumannii
           (strain ATCC 17978 / NCDC KC 755)
          Length = 231

 Score =  151 bits (367), Expect = 9e-36
 Identities = 70/145 (48%), Positives = 103/145 (71%), Gaps = 3/145 (2%)
 Frame = +2

Query: 164 KSVIGKDSGAQA-DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLL 340
           KSV+ ++S     DI + DG +++ G+  + A  TPGHTN C +Y+    ++ FTGD LL
Sbjct: 76  KSVLHRNSEVSCGDILITDGCMLKVGNLSIEARYTPGHTNACTSYLVG--NMIFTGDALL 133

Query: 341 IRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL-- 514
           I GCGRTDFQ+GN+ TLY S+H ++F+LPD  +LYP HDY+G+ ++++  E+  N RL  
Sbjct: 134 IDGCGRTDFQQGNAGTLYDSIHKQLFSLPDNTILYPGHDYKGRLSSTIGYERLNNSRLGQ 193

Query: 515 TKSLAEFVEIMDNLNLPYPKMINKA 589
            +S  +F+E+M+NLNLPYPK I+KA
Sbjct: 194 NRSREDFIELMNNLNLPYPKQIDKA 218


>UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein;
           n=6; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Nitrosococcus oceani (strain ATCC 19707 /
           NCIMB 11848)
          Length = 361

 Score =  149 bits (361), Expect = 5e-35
 Identities = 76/147 (51%), Positives = 102/147 (69%), Gaps = 3/147 (2%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGS-HELLAAATPGHTNGCLTYICHEQSLAFTGD 331
           G K+ IG+  GAQ AD  L DG ++ FG   E+   ATPGHT G ++Y+  ++   FTGD
Sbjct: 74  GAKTGIGQACGAQYADYQLKDGVVLAFGQGEEIKVLATPGHTPGSISYLWRDR--VFTGD 131

Query: 332 TLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPR 511
            LLI GCGRTDFQ G+  TLY SV  ++FTLP E ++YP HDY G+  +SV +E+  N R
Sbjct: 132 ALLINGCGRTDFQGGDPGTLYDSVTQKLFTLPGETIVYPGHDYNGRWVSSVEQERTGNGR 191

Query: 512 LT-KSLAEFVEIMDNLNLPYPKMINKA 589
           L  K+ AEF+EIM+NLNLP P++I++A
Sbjct: 192 LAGKTRAEFIEIMNNLNLPKPRLIDEA 218


>UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2;
           Synechococcus|Rep: Beta-lactamase-like - Synechococcus
           sp. RS9917
          Length = 370

 Score =  147 bits (356), Expect = 2e-34
 Identities = 75/148 (50%), Positives = 99/148 (66%), Gaps = 5/148 (3%)
 Frame = +2

Query: 161 TKSVIGKDSGAQADI---HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGD 331
           T + IG  + A+A+     L  GD V FG+  L   ATPGHT+GCLT++  + S AFTGD
Sbjct: 88  TGAAIGLAAAARAENVTQPLQHGDRVGFGARALEVRATPGHTDGCLTFVLDDASAAFTGD 147

Query: 332 TLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPR 511
            LLIRGCGR+DFQ+GN+ TLY+S+  +I +LPD+ +LYP HDY G+  TSVAEE+  N R
Sbjct: 148 ALLIRGCGRSDFQQGNAHTLYRSITEQILSLPDQCLLYPGHDYSGRQVTSVAEERALNAR 207

Query: 512 LTKSLAE--FVEIMDNLNLPYPKMINKA 589
           L     E  FV  M++L LP+P  I +A
Sbjct: 208 LGGGADERDFVIHMESLKLPHPHRIAQA 235


>UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamily
           protein; n=11; Bacteria|Rep: Possible
           Beta-lactamase-like superfamily protein - Psychrobacter
           arcticum
          Length = 249

 Score =  138 bits (335), Expect = 7e-32
 Identities = 69/135 (51%), Positives = 92/135 (68%), Gaps = 2/135 (1%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+ L +G  ++     L    TPGHT+G   Y+ +EQ   FTGD LLI GCGRTDFQ G+
Sbjct: 89  DVGLEEGTPLQVAGITLHPLHTPGHTDGHFAYLFNEQ--VFTGDALLIDGCGRTDFQNGD 146

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTK--SLAEFVEIMDN 553
           ++ LYKSV  ++F+LPD+ ++YPAHDY+    +S+A+EKK NPRL +  +L EF  IM N
Sbjct: 147 ADALYKSVRQKLFSLPDDTLVYPAHDYKECFVSSIAQEKKRNPRLGEDITLEEFKVIMSN 206

Query: 554 LNLPYPKMINKAGAG 598
           LNLPYPK I+ A  G
Sbjct: 207 LNLPYPKFIDYAVPG 221


>UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|Rep:
           Bll1007 protein - Bradyrhizobium japonicum
          Length = 345

 Score =  137 bits (331), Expect = 2e-31
 Identities = 67/143 (46%), Positives = 95/143 (66%), Gaps = 2/143 (1%)
 Frame = +2

Query: 167 SVIGKDSGAQA-DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI 343
           +V+G  + A    + + DGD V      L    TPGHT+   +Y+  ++   FTGDTLLI
Sbjct: 77  TVMGDQTKADVVAMRVADGDKVTIEGLSLDVMYTPGHTDDSYSYLMGDR--VFTGDTLLI 134

Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL-TK 520
           RG GRTDFQ G+S   Y S+ NR+  LPDE +++PAHDY+G T +++ EEK+YNPRL  +
Sbjct: 135 RGTGRTDFQNGSSRAQYDSIFNRLLKLPDETMVFPAHDYKGDTVSTIGEEKRYNPRLQVR 194

Query: 521 SLAEFVEIMDNLNLPYPKMINKA 589
           S+ E++E+M NL LP PKM++ A
Sbjct: 195 SVDEYIELMANLKLPNPKMMDVA 217


>UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Thiomicrospira crunogena XCL-2|Rep:
           Metallo-beta-lactamase superfamily protein -
           Thiomicrospira crunogena (strain XCL-2)
          Length = 229

 Score =  137 bits (331), Expect = 2e-31
 Identities = 67/150 (44%), Positives = 101/150 (67%), Gaps = 3/150 (2%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334
           G + V+ K+SG++ ADI  +DGD+ + G  E+    TPGHTN  +TY    +   FTGDT
Sbjct: 74  GGQLVVHKNSGSECADILAVDGDVFKLGDQEIHVLHTPGHTNNDITY--QIEGAVFTGDT 131

Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           L++R CGRTDFQ G+++ +Y S+   +F LP++ +++PAHDY+G + +++ EEK++N R 
Sbjct: 132 LMVRDCGRTDFQLGDNKAMYHSLTEILFKLPEDTMVFPAHDYKGFSQSTIGEEKQFNNRA 191

Query: 515 --TKSLAEFVEIMDNLNLPYPKMINKAGAG 598
              KS  +F  IMD+LNLP PK I+ A  G
Sbjct: 192 GSNKSYEDFSTIMDSLNLPNPKRIDIAVPG 221


>UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15;
           Gammaproteobacteria|Rep: Zn-dependent hydrolase -
           Francisella tularensis subsp. novicida (strain U112)
          Length = 228

 Score =  137 bits (331), Expect = 2e-31
 Identities = 70/146 (47%), Positives = 98/146 (67%), Gaps = 2/146 (1%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334
           G   VIG +S A+ A   + DGD++ FG+++L A  TPGHT+    +I   +++ FTGDT
Sbjct: 74  GCDIVIGGESKAECATKKVFDGDILEFGNYQLKALYTPGHTDDSYCFIT--ENMLFTGDT 131

Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           LLIRG GRTDFQ G+S   Y S+ N++ TLP   ++YP HDY G T++SVAEE++ NPRL
Sbjct: 132 LLIRGSGRTDFQNGDSYAAYDSIMNKLMTLPGSTIIYPGHDYNGITSSSVAEERQNNPRL 191

Query: 515 -TKSLAEFVEIMDNLNLPYPKMINKA 589
             KS  E+ ++M +L LP P  I+ A
Sbjct: 192 KVKSPDEYAKLMADLKLPPPNYIDIA 217


>UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1;
           Candidatus Ruthia magnifica str. Cm (Calyptogena
           magnifica)|Rep: Beta-lactamase domain protein - Ruthia
           magnifica subsp. Calyptogena magnifica
          Length = 236

 Score =  136 bits (329), Expect = 4e-31
 Identities = 66/133 (49%), Positives = 93/133 (69%), Gaps = 2/133 (1%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           ADI L D D + FG + L A ATPGHT+GC++Y+ + Q   FTGDTLLIR CGR DFQ G
Sbjct: 91  ADILLNDNDTLSFGDYTLSAMATPGHTDGCMSYVVNNQ--IFTGDTLLIRSCGRCDFQGG 148

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSL--AEFVEIMD 550
           ++E L+ S+  +IFTLPDE ++YPAHDY G+T +S+ EEK++N  +  ++   EF   ++
Sbjct: 149 SAEKLFDSIQ-KIFTLPDETLVYPAHDYGGRTVSSIWEEKQFNEMIGSNVNKQEFTRRVN 207

Query: 551 NLNLPYPKMINKA 589
            + L +PK I+ A
Sbjct: 208 TMKLDFPKKIHVA 220


>UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein;
           n=14; Bacteria|Rep: Metallo-beta-lactamase domain
           protein - Synechococcus sp. (strain JA-2-3B'a(2-13))
           (Cyanobacteria bacteriumYellowstone B-Prime)
          Length = 238

 Score =  130 bits (314), Expect = 2e-29
 Identities = 70/160 (43%), Positives = 99/160 (61%), Gaps = 8/160 (5%)
 Frame = +2

Query: 134 GKLKSLVPGTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQ 310
           GKL+ L  G + V+   + AQ AD  +  G+ ++ GS  + A AT GHT+  +TY  +  
Sbjct: 67  GKLRELT-GCQGVVPVQAKAQCADRFIGHGETLQVGSVVIEAIATLGHTDSHMTYRVNGD 125

Query: 311 SLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAE 490
            +  TGD LLIRGCGRTDFQ G+   +Y  V   +FTLPDE ++YP HDYRG T +++ E
Sbjct: 126 RV-LTGDALLIRGCGRTDFQSGDPGLMYDHVTQHLFTLPDETLVYPGHDYRGHTVSTIGE 184

Query: 491 EKKYNPRLT-------KSLAEFVEIMDNLNLPYPKMINKA 589
           EK++NPR         +S   F+ +M++LNLP PK I +A
Sbjct: 185 EKRWNPRFVDPETGNLRSRESFIALMNSLNLPQPKKIQEA 224


>UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas sp.
           JS666|Rep: Beta-lactamase-like - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 346

 Score =  103 bits (246), Expect = 4e-21
 Identities = 55/146 (37%), Positives = 86/146 (58%), Gaps = 2/146 (1%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQA-DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334
           G  +V+ + S A   D+ + DG+++  G   L    TPGHT   +  +  ++   FTGDT
Sbjct: 72  GAMTVMHRASPAPGVDLRVDDGEMIVLGKLRLQVLYTPGHTVDSMCLVADDR--VFTGDT 129

Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           LLI G GRTD   G+ E LY S+  R+  L    ++YPAHDY+G++ +++ +E   NPRL
Sbjct: 130 LLIGGTGRTDLPTGDPEALYDSLFGRLLKLDPALLVYPAHDYKGRSHSTIGDEIATNPRL 189

Query: 515 TKS-LAEFVEIMDNLNLPYPKMINKA 589
            ++  A FVE+M +L+L  P  + +A
Sbjct: 190 QRTDRAAFVEMMKSLDLSMPTHLTEA 215


>UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1;
           Shewanella sediminis HAW-EB3|Rep: Beta-lactamase domain
           protein - Shewanella sediminis HAW-EB3
          Length = 354

 Score = 91.5 bits (217), Expect = 1e-17
 Identities = 49/131 (37%), Positives = 73/131 (55%), Gaps = 1/131 (0%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+++ DG+++  G   L    TPGHT   +  +  ++   FTGDTLL+ G GRTD   G+
Sbjct: 90  DMYVDDGEIIIVGKLRLTIMHTPGHTADSICIVMKDR--VFTGDTLLLGGTGRTDLPSGD 147

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL-TKSLAEFVEIMDNL 556
            E LY S+ N +  L  +  +YPAH Y  +T +S+ EE   NPRL  K   EFV  M  +
Sbjct: 148 PERLYDSLFNGLLKLSADLKVYPAHAYSERTHSSIGEELSNNPRLQKKDRDEFVAQMRAI 207

Query: 557 NLPYPKMINKA 589
           +L  P  + ++
Sbjct: 208 DLKMPTQLTES 218


>UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3;
           Deltaproteobacteria|Rep: Beta-lactamase-like - delta
           proteobacterium MLMS-1
          Length = 213

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 51/120 (42%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
 Frame = +2

Query: 167 SVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNG--CLTYICHEQSLAFTGDTLL 340
           S++G  +    D  L DGD V  G+ EL    TPGHT G  CL    H     FTGDTL 
Sbjct: 96  SMLGLPASPPPDRLLQDGDTVVLGTIELQVIHTPGHTPGGICLYTAPH----LFTGDTLF 151

Query: 341 IRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTK 520
           + G GRTDF  G++ TL  S+  R+  LP E V++P H Y G  +T + EE + NP L++
Sbjct: 152 VGGVGRTDFPGGDTATLVNSLQQRLLKLPPETVVWPGHGYGGARST-IGEEARDNPYLSE 210


>UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium
           phytofermentans ISDg|Rep: Beta-lactamase-like -
           Clostridium phytofermentans ISDg
          Length = 216

 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 44/114 (38%), Positives = 61/114 (53%)
 Frame = +2

Query: 167 SVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIR 346
           S+ GK         L D + ++F   E +   TPGHT G + Y   ++ +  +GDTL   
Sbjct: 98  SIFGKSLTLAPVESLHDLEKIQFADIEFVVLHTPGHTKGSVCYYIPDEQILLSGDTLFFE 157

Query: 347 GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
             GRTDF  GNSE L KS++ R+FTLP E  +YP H      +TS+  E + NP
Sbjct: 158 SVGRTDFPTGNSEVLVKSINERLFTLPKEVKVYPGHG----CSTSIGYEMQNNP 207


>UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 209

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 39/105 (37%), Positives = 59/105 (56%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           +AD++L D  +V      +    TPGHT G   Y   ++ + F+GDT+     GRTDF E
Sbjct: 107 KADVYLTDLQVVELAGFSVQMIETPGHTLGSCCYYLKDEGVLFSGDTVFCGSVGRTDFPE 166

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           G++  +  S+H  +  LPD   +YP HD    T+T++  EK+YNP
Sbjct: 167 GSTAAIVNSLHRLLEALPDNTEVYPGHD----TSTTIGYEKRYNP 207


>UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1;
           Syntrophus aciditrophicus SB|Rep: Hydroxyacylglutathione
           hydrolase W - Syntrophus aciditrophicus (strain SB)
          Length = 257

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 45/118 (38%), Positives = 67/118 (56%), Gaps = 3/118 (2%)
 Frame = +2

Query: 170 VIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNG--CLTYICHEQSLAFTGDTLLI 343
           + G +    AD+ + DGD +  G   L    TPGH+ G  CL YI   +   FTGDTL +
Sbjct: 144 MFGAEDSPPADMTVKDGDTITVGKISLKVIHTPGHSPGGMCL-YI---KGFVFTGDTLFV 199

Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATS-VAEEKKYNPRL 514
              GRTD    ++  +++S+  ++ TLPD+  + P H+Y G+T+TS +  EK YNP L
Sbjct: 200 ESVGRTDLNGSSASQMFRSIREKLLTLPDDTQVLPGHNY-GRTSTSTIGHEKIYNPFL 256


>UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 214

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 45/121 (37%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNG-CLTYICHEQSLAFTGDT 334
           G   ++G      AD+ + DGD + FG+  +    TPGHT G C   I       FTGDT
Sbjct: 93  GFARMMGFQPAPPADVRVEDGDELTFGNLTMKFINTPGHTPGSCCVLI---DGNLFTGDT 149

Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           L +   GRTD   G+   L +S+  +I TLP + V++P HDY  +  ++V  E K NP +
Sbjct: 150 LFVGAVGRTDLPGGSFGELIQSLKTKIVTLPPDTVVWPGHDYGDRPFSTVKHEMKTNPYI 209

Query: 515 T 517
           T
Sbjct: 210 T 210


>UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2;
           Thermoprotei|Rep: Zn-dependent hydrolase - Cenarchaeum
           symbiosum
          Length = 203

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 43/131 (32%), Positives = 68/131 (51%), Gaps = 1/131 (0%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTL 337
           G + +  ++S  + DI + DG  +R GS  L    TPGH+   +  +       FTGDTL
Sbjct: 73  GARIIQHEESELKHDITVRDGSEIRIGSTMLSVLHTPGHSRDSICLV--GDGKIFTGDTL 130

Query: 338 LIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517
            +  CGR D   G++  LY S+   ++ L D  V+Y  HDY     +++ +EKK NP + 
Sbjct: 131 FVGSCGRVDLPGGSARDLYGSIFGVLYRLDDSLVVYCGHDYGTSPVSTLGDEKKSNPVMR 190

Query: 518 K-SLAEFVEIM 547
           +    +FV +M
Sbjct: 191 RVGEEQFVAMM 201


>UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor;
           n=5; Desulfuromonadales|Rep: Beta-lactamase domain
           protein precursor - Geobacter uraniumreducens Rf4
          Length = 251

 Score = 80.2 bits (189), Expect = 3e-14
 Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
 Frame = +2

Query: 182 DSGAQADIHLLDGDLVRFGSHELLAAATPGHT-NGCLTYICHEQSLAFTGDTLLIRGCGR 358
           ++  + D  L DG +V FGS +L    TPGHT  GC  Y+   +    TGDTL   G GR
Sbjct: 142 ENSPKPDGLLEDGMVVIFGSQQLKVLHTPGHTPGGCCLYL-ESEGKVITGDTLFADGVGR 200

Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           TDF   + E L + + N++FTLP+  ++YP H      ++++  EK  NP
Sbjct: 201 TDFPGSSHEALIEGIRNKLFTLPEPTLVYPGHG----PSSNIGHEKSNNP 246


>UniRef50_Q6MNF6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=3; Proteobacteria|Rep: Metallo-beta-lactamase
           superfamily protein - Bdellovibrio bacteriovorus
          Length = 286

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 51/143 (35%), Positives = 80/143 (55%), Gaps = 11/143 (7%)
 Frame = +2

Query: 185 SGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGR 358
           SG+  DI L +G++++ GS ++    TPGHT  C +Y+  +    FTGD L +   G GR
Sbjct: 116 SGSDFDILLKEGEVLQAGSLKIKTLFTPGHTPACASYLIEDA--IFTGDALFMPDSGTGR 173

Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYR--GQT---ATSVAEEKKYNPRLT-- 517
            DF  G++E LY SV  +I++LP+   ++  HDY+  G+     T+V EEK  N +L   
Sbjct: 174 CDFPAGSAENLYDSVTGKIYSLPENTRIFVGHDYQPNGRALMYQTTVNEEKNQNIQLKGH 233

Query: 518 KSLAEFVEIMD--NLNLPYPKMI 580
            S  +FV+     +  L  PK++
Sbjct: 234 TSKEDFVKFRQERDATLAAPKLL 256


>UniRef50_Q0SRP5 Cluster: Metallo-beta-lactamase family protein;
           n=8; Clostridium|Rep: Metallo-beta-lactamase family
           protein - Clostridium perfringens (strain SM101 / Type
           A)
          Length = 206

 Score = 79.4 bits (187), Expect = 6e-14
 Identities = 43/108 (39%), Positives = 67/108 (62%), Gaps = 1/108 (0%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFG-SHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370
           +AD +L DGD ++F  ++E+    TPGHT G L ++    +  FTGDTL     GR+DF+
Sbjct: 98  KADGYLKDGDTLKFSDNYEIKCLETPGHTPGGLCFLI--DNCLFTGDTLFRESIGRSDFE 155

Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
            GN  TL KS+++++  L D+ V+YP H   G ++T +  E++ NP L
Sbjct: 156 GGNHATLLKSINDKLVPLGDDIVVYPGH---GPSST-IKHERQRNPFL 199


>UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep:
           Hydroxyacylglutathione hydrolase W - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 220

 Score = 79.4 bits (187), Expect = 6e-14
 Identities = 39/113 (34%), Positives = 59/113 (52%)
 Frame = +2

Query: 170 VIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRG 349
           ++G     + D+ L  G+ V  G   L    TPGHT G +    +     F GDTL +  
Sbjct: 105 LLGGRPSPRPDVVLQHGEAVVLGQTTLTVLHTPGHTPGSICL--YMPGHLFAGDTLFVGS 162

Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            GRTD   G+ + L+ S+  R+F LPD+  ++P HDY  +  +++  EKK NP
Sbjct: 163 AGRTDLSGGSIKDLHASIRTRLFPLPDDTRVWPGHDYGDRPVSTIGHEKKTNP 215


>UniRef50_Q1IQE8 Cluster: Beta-lactamase-like; n=2;
           Acidobacteria|Rep: Beta-lactamase-like - Acidobacteria
           bacterium (strain Ellin345)
          Length = 209

 Score = 79.0 bits (186), Expect = 8e-14
 Identities = 42/113 (37%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
 Frame = +2

Query: 179 KDSG-AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCG 355
           KD G    D  L DGD V+FG+ E     TPGHT G +  +   +     GDTL     G
Sbjct: 99  KDPGKVVVDESLADGDSVKFGTIEGSVIHTPGHTQGSICLLLKSEKTLIAGDTLFQGSIG 158

Query: 356 RTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           RTD   G+ E + KS+H ++  LP E ++ P H      +T++ EE++ NP L
Sbjct: 159 RTDLPGGSYEKIMKSIHGKLLVLPGETIVIPGHG----PSTTIEEERERNPFL 207


>UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Dichelobacter nodosus VCS1703A|Rep:
           Metallo-beta-lactamase superfamily protein -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 235

 Score = 79.0 bits (186), Expect = 8e-14
 Identities = 46/118 (38%), Positives = 69/118 (58%), Gaps = 2/118 (1%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNG-CLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385
           L DGD +  G+  +   ATPGHT G C  Y+  + +L  TGDTL + GCGRTDF  G+S 
Sbjct: 95  LQDGDEIFCGADVIQMIATPGHTAGSCCFYV--DNNL-ITGDTLFVYGCGRTDFPSGDSR 151

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEFVEIMDNL 556
            L++S+  ++  LP    +   HDY  +  ++++E+  YNP +T  SL +FV   + L
Sbjct: 152 ALFESL-QKLKKLPPHTQILSGHDYGIEKNSTLSEQITYNPFMTICSLDDFVRFREEL 208


>UniRef50_Q64UQ6 Cluster: Putative metallo-beta-lactamase; n=5;
           Bacteroides|Rep: Putative metallo-beta-lactamase -
           Bacteroides fragilis
          Length = 212

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 38/101 (37%), Positives = 55/101 (54%)
 Frame = +2

Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385
           +L DGD++ FG+  L A   PGH+ G L Y C   +  F+GD L     GR D   GN +
Sbjct: 113 YLHDGDIITFGNTTLEAIHVPGHSPGSLVYYCRADNCMFSGDVLFQGSIGRADLAGGNFD 172

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            L + + +R+F LP+E ++YP H       T++  EK  NP
Sbjct: 173 ELKEHICSRLFVLPNETIVYPGHG----APTTIGIEKAENP 209


>UniRef50_Q1ZAD4 Cluster: Probable metallo-beta-lactamase
           superfamily protein; n=1; Photobacterium profundum
           3TCK|Rep: Probable metallo-beta-lactamase superfamily
           protein - Photobacterium profundum 3TCK
          Length = 260

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 51/144 (35%), Positives = 80/144 (55%), Gaps = 11/144 (7%)
 Frame = +2

Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRTD 364
           AQ D+ L +GD +  G  ++   +TPGHT   LTY  H     F GDTL    RG GR D
Sbjct: 107 AQFDVLLDEGDELSLGGEKVSVLSTPGHTPADLTY--HIGDSIFVGDTLFAPKRGTGRAD 164

Query: 365 FQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQT-----ATSVAEEKKYNPRLTKSLA 529
           F  G+++ LY+S+ +R+F LP++  +Y  HDY  +       +S++ +K  N  +  S+ 
Sbjct: 165 FPGGSAKDLYRSI-SRLFELPEDTDVYLCHDYPSENEEPELCSSLSTQKSDNVMINTSVT 223

Query: 530 E--FVEIMD--NLNLPYPKMINKA 589
           E  ++EI    + NL  PK+++ A
Sbjct: 224 EKQYIEIRTKRDSNLATPKLLDVA 247


>UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Clostridium|Rep: Hydroxyacylglutathione hydrolase -
           Clostridium tetani
          Length = 201

 Score = 78.2 bits (184), Expect = 1e-13
 Identities = 42/124 (33%), Positives = 67/124 (54%)
 Frame = +2

Query: 143 KSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAF 322
           +S++ G        +   ADI + +GD  + G  E+    TPGH+ G + ++   +++ F
Sbjct: 84  ESILKGMDLFGNSQTCGAADIKIKEGDTFKIGDKEIKCIETPGHSLGGMCFLI--ENIIF 141

Query: 323 TGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKY 502
           TGDTL     GRTDF  GN E L K++  +I T+P++ ++ P H       T+V +EK  
Sbjct: 142 TGDTLFEGSIGRTDFYGGNFEILIKNIKEKILTIPEDTLVLPGHGME----TTVGKEKIS 197

Query: 503 NPRL 514
           NP L
Sbjct: 198 NPFL 201


>UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein;
           n=4; Desulfuromonadales|Rep: Metallo-beta-lactamase
           family protein - Geobacter sulfurreducens
          Length = 209

 Score = 78.2 bits (184), Expect = 1e-13
 Identities = 42/106 (39%), Positives = 54/106 (50%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L DG  +  G+  L    TPGHT G    +   +    TGDTL     GRTDF   +
Sbjct: 107 DSLLEDGMTLSVGTLSLRVLHTPGHTPGGCCLLLEGEGKVLTGDTLFEESVGRTDFPGSS 166

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517
            E L  S+  ++ TLPDE  +YP H      ATS+  E++YNP LT
Sbjct: 167 HEALITSIREKLLTLPDETEVYPGHG----PATSIGRERRYNPYLT 208


>UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein;
           n=1; Plesiocystis pacifica SIR-1|Rep:
           Metallo-beta-lactamase family protein - Plesiocystis
           pacifica SIR-1
          Length = 234

 Score = 78.2 bits (184), Expect = 1e-13
 Identities = 42/109 (38%), Positives = 62/109 (56%), Gaps = 2/109 (1%)
 Frame = +2

Query: 218 GDLVRFGSH-ELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           GD VR G   E+    TPGHT G  +Y   +  +  TGDTL + GCGR DF  G+ E ++
Sbjct: 104 GDTVRVGEQLEITMMHTPGHTPGSCSYRLRDSIV--TGDTLFVNGCGRCDFVGGDPELMF 161

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEFV 538
           +++   +  LP + V+YP H Y    + +V E+ + NP L   ++AEFV
Sbjct: 162 ETLEALMSKLPKDTVMYPGHHYGPTPSATVDEQLRDNPYLKHTTVAEFV 210


>UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein;
           n=1; Lentisphaera araneosa HTCC2155|Rep:
           Metallo-beta-lactamase family protein - Lentisphaera
           araneosa HTCC2155
          Length = 222

 Score = 78.2 bits (184), Expect = 1e-13
 Identities = 49/134 (36%), Positives = 75/134 (55%), Gaps = 6/134 (4%)
 Frame = +2

Query: 185 SGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHE-QSLAFTGDTLLIRGCGRT 361
           +G  A +H   GD ++ GS EL    TPGHT G    +C+E  +  FTGDT+ + GCGR 
Sbjct: 90  AGRNAKLHS-GGDFIKLGSIELKIHHTPGHTPGS---VCYELDNHLFTGDTVFVYGCGRC 145

Query: 362 DFQEGNSETLYKSVHNRIFTLPD-EYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEF 535
           + + G+ E +Y ++ N+I T  D    + P HDY     +++AE+ + NP    K+L EF
Sbjct: 146 NLRGGDPEAMYHTL-NKIGTNFDPSMTVLPGHDYASCATSTIAEQLQGNPFFNIKTLHEF 204

Query: 536 VEI---MDNLNLPY 568
           V+      N ++PY
Sbjct: 205 VDYRMHKHNRSIPY 218


>UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including
           glyoxylases; n=2; Thermoanaerobacter|Rep: Zn-dependent
           hydrolases, including glyoxylases - Thermoanaerobacter
           tengcongensis
          Length = 214

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 44/103 (42%), Positives = 60/103 (58%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           ADI L D D++ FG++ +   +TPGHT G + +   +  + FTGDTL     GR DF  G
Sbjct: 111 ADIILKDKDVLGFGNYYVEVISTPGHTKGSVCFKIGD--VYFTGDTLFRGSIGRHDFPGG 168

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
           N ETL  S+  R+ TL DE V+YP H   G  +T +  EK+ N
Sbjct: 169 NFETLMASIKERLLTLKDETVIYPGH---GDFST-IGREKRLN 207


>UniRef50_A6L4P4 Cluster: Putative metallo-beta-lactamase; n=2;
           Bacteroidales|Rep: Putative metallo-beta-lactamase -
           Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC
           11154)
          Length = 212

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 37/101 (36%), Positives = 55/101 (54%)
 Frame = +2

Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385
           ++ DGD++ FG+ +L A   PGH+ G + + C E    F+GD L     GR D   GN +
Sbjct: 113 YIFDGDIITFGNTQLEAIHVPGHSPGSIVFYCKEAHCIFSGDVLFQGSIGRADLTGGNFD 172

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            L + + +R+F LP + V+YP H       T+V  EK  NP
Sbjct: 173 ELREHICSRLFVLPPDTVVYPGHG----DPTTVGAEKANNP 209


>UniRef50_Q1PVC6 Cluster: Similar to hydroxyacylglutathione
           hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
           Similar to hydroxyacylglutathione hydrolase - Candidatus
           Kuenenia stuttgartiensis
          Length = 210

 Score = 77.4 bits (182), Expect = 2e-13
 Identities = 38/105 (36%), Positives = 59/105 (56%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           + D +L+D + +  G   +    TPGH+ GC+ ++ +  +  F GDTL     GRTD   
Sbjct: 110 KVDRYLIDNEELPLGDEVIRIIHTPGHSPGCVCFLFN--NAIFAGDTLFAGSVGRTDLYG 167

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           G+ +TL  SV  R+FTL D  ++YP H       T++ +EKK+NP
Sbjct: 168 GSHDTLINSVKTRLFTLEDHVLVYPGHG----PVTTIGKEKKHNP 208


>UniRef50_A3SZ22 Cluster: Beta-lactamase-like; n=6;
           Proteobacteria|Rep: Beta-lactamase-like - Sulfitobacter
           sp. NAS-14.1
          Length = 306

 Score = 77.4 bits (182), Expect = 2e-13
 Identities = 53/142 (37%), Positives = 74/142 (52%), Gaps = 11/142 (7%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361
           G+Q D    DGD  R G  E  A  TPGHT  C+ ++    + AFTGDTL +   G  R 
Sbjct: 138 GSQFDALFKDGDRYRVGGMECFAIYTPGHTPACMVHVM--GNAAFTGDTLFMPDGGSARA 195

Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY--RG---QTATSVAEEKKYNPRL--TK 520
           DF  G++  LY S+  ++ +LPD+  L+  HDY   G   Q  T+V EEK +N  +   K
Sbjct: 196 DFPGGDAGELYDSI-QKVLSLPDDMRLFMCHDYGPNGRDIQWETTVGEEKAHNIHVGGGK 254

Query: 521 SLAEFVEIMD--NLNLPYPKMI 580
           +  EF+      +  L  PK+I
Sbjct: 255 TREEFIAFRTERDAQLSMPKLI 276


>UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 215

 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 41/104 (39%), Positives = 56/104 (53%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           AD  L +GD++ FG   L    TPGHT G ++    E    F GDT+     GRTDF  G
Sbjct: 113 ADRTLEEGDVLDFGPIRLSVIETPGHTPGHVSVYFPEAKSIFVGDTIFAGSIGRTDFPGG 172

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           + + L +SV  +IFTLP + ++YP H       T+V  E + NP
Sbjct: 173 SHDRLIRSVKEKIFTLPGDTLVYPGHG----PGTTVEREMRTNP 212


>UniRef50_A1VR45 Cluster: Beta-lactamase domain protein; n=1;
           Polaromonas naphthalenivorans CJ2|Rep: Beta-lactamase
           domain protein - Polaromonas naphthalenivorans (strain
           CJ2)
          Length = 215

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 40/99 (40%), Positives = 58/99 (58%), Gaps = 1/99 (1%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAA-ATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETL 391
           DGDL+ FG HELL   ATPGHT GCL++   ++   F G  L +  C          E L
Sbjct: 91  DGDLLPFG-HELLRVLATPGHTAGCLSFAWRDR--LFCGGLLAVDACPHQPIP-AQPEAL 146

Query: 392 YKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           + SV  R+FTLPDE +L+  H  R +  ++V E+++++P
Sbjct: 147 WDSVTQRVFTLPDETLLFAGHGRRARAVSTVLEQRRWHP 185


>UniRef50_A6L981 Cluster: Metallo-beta-lactamase family protein;
           n=1; Parabacteroides distasonis ATCC 8503|Rep:
           Metallo-beta-lactamase family protein - Parabacteroides
           distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 212

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 34/103 (33%), Positives = 57/103 (55%)
 Frame = +2

Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385
           +L++G++++FG  EL   + PGH+ G + +   +      GD+L     GRTD   GN +
Sbjct: 114 YLVNGEIIKFGKSELAVLSVPGHSPGGVAFYNKKNGFVIVGDSLFAGSIGRTDLWGGNQD 173

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
            L  ++ +++ +LPDE V+YP H       T + +EK  NP L
Sbjct: 174 ILLAAIKDKLLSLPDETVVYPGHG----PETRIIDEKLNNPYL 212


>UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein;
           n=1; Porphyromonas gingivalis|Rep:
           Metallo-beta-lactamase family protein - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 214

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 38/103 (36%), Positives = 55/103 (53%)
 Frame = +2

Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385
           ++  GD+++ G   +     PGH+ G L + C +    FTGD L     GRTD   G+ E
Sbjct: 115 YIAPGDVLQLGESIIKVLFVPGHSPGHLAFYCPQAQAVFTGDALFAGDMGRTDLWGGSYE 174

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
            L KS+   +  LPD+ V+YP H   G T+T +A E+  NP L
Sbjct: 175 LLKKSIRTELLPLPDDTVVYPGH---GPTST-IAYERTNNPFL 213


>UniRef50_A4AWZ7 Cluster: Putative uncharacterized protein; n=2;
           Proteobacteria|Rep: Putative uncharacterized protein -
           Alteromonas macleodii 'Deep ecotype'
          Length = 284

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 46/142 (32%), Positives = 73/142 (51%), Gaps = 11/142 (7%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361
           G+Q D+   +GD    G +E+    TPGHT  C +++       F GDT+     G  R 
Sbjct: 115 GSQFDVLFEEGDTFNIGEYEVTVWHTPGHTPACASFLV--DGKIFVGDTMFAPNLGTARC 172

Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQ-----TATSVAEEKKYNPRLTK-- 520
           DF  G++E LY ++  R FTLPD+  +Y  HDY  +     +  S+ E K+ N ++    
Sbjct: 173 DFPGGSAEQLYNTI-QRFFTLPDDTTVYLGHDYPKEGTAPLSTVSIKEAKETNKQIRPEV 231

Query: 521 SLAEFVEIMD--NLNLPYPKMI 580
           +L E+VE  +  +  L  PK++
Sbjct: 232 TLQEYVEKREARDATLAVPKLL 253


>UniRef50_Q57544 Cluster: Uncharacterized protein HI1663; n=20;
           Pasteurellaceae|Rep: Uncharacterized protein HI1663 -
           Haemophilus influenzae
          Length = 212

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 35/100 (35%), Positives = 56/100 (56%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           +G++++           PGHT G + +I HE+ +AFTGD L   G GRTDF  G+ ETL 
Sbjct: 113 EGEILKLDGFNFEILHLPGHTPGHIGFIEHEKKVAFTGDVLFQGGIGRTDFPRGDYETLI 172

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
            S+  ++  L D+ ++   H     + T++ +EK+ NP L
Sbjct: 173 SSIRTKLLPLNDDIIIIAGHG----SYTTIGQEKRSNPFL 208


>UniRef50_Q314Q9 Cluster: Metallo-beta-lactamase family protein;
           n=3; Desulfovibrio|Rep: Metallo-beta-lactamase family
           protein - Desulfovibrio desulfuricans (strain G20)
          Length = 208

 Score = 72.9 bits (171), Expect = 5e-12
 Identities = 38/86 (44%), Positives = 47/86 (54%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGHT G  ++   +    F GD L  R  GRTDF  G+S TL  SV   IF+LPD  V+
Sbjct: 124 TPGHTPGSFSFYFPQAEAVFVGDLLFHRSVGRTDFPGGDSATLLNSVKKAIFSLPDTTVV 183

Query: 443 YPAHDYRGQTATSVAEEKKYNPRLTK 520
           YP H       T+V +EK  NP  T+
Sbjct: 184 YPGHGIE----TTVGDEKLNNPFFTE 205


>UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3;
           Cystobacterineae|Rep: Myofibrillogenesis regulator 1 -
           Stigmatella aurantiaca DW4/3-1
          Length = 220

 Score = 72.9 bits (171), Expect = 5e-12
 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
 Frame = +2

Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397
           G+ +  G    LA  TPGHT G    +  +  ++  GDT+ I GCGR D + GN E +Y+
Sbjct: 107 GEALTVGPRTFLALHTPGHTPGSHCLLAGDALVS--GDTVFINGCGRCDMRGGNPEDMYR 164

Query: 398 SVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEFV 538
           S+   +  +PDE  L+P HDY      ++ + ++ NP      +A FV
Sbjct: 165 SLSQVLLRVPDETRLWPGHDYAEVPVAAMGQVRQANPYFAFPDVASFV 212


>UniRef50_A6EK80 Cluster: Metallo-beta-lactamase family protein;
           n=1; Pedobacter sp. BAL39|Rep: Metallo-beta-lactamase
           family protein - Pedobacter sp. BAL39
          Length = 220

 Score = 72.9 bits (171), Expect = 5e-12
 Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 2/123 (1%)
 Frame = +2

Query: 152 VPGTKSVIGK--DSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFT 325
           +PG    +G   +   + ++ L +   V FG   L     PGH+   L +   E      
Sbjct: 101 IPGYAPQMGLSYELSPEPEVFLPEQGTVEFGKSALELIFVPGHSPAHLCFHAREDGFLIG 160

Query: 326 GDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
           GD L  R  GRTD   GN + L  S+ N +F LPD+ V+YP H   GQ +T++  E+++N
Sbjct: 161 GDALFYRSIGRTDLPGGNHDQLISSIRNNLFILPDDCVVYPGH---GQ-STTIGFEREHN 216

Query: 506 PRL 514
           P L
Sbjct: 217 PFL 219


>UniRef50_A4C5I4 Cluster: Beta-lactamase-like protein; n=1;
           Pseudoalteromonas tunicata D2|Rep: Beta-lactamase-like
           protein - Pseudoalteromonas tunicata D2
          Length = 283

 Score = 72.9 bits (171), Expect = 5e-12
 Identities = 52/140 (37%), Positives = 71/140 (50%), Gaps = 12/140 (8%)
 Frame = +2

Query: 206 HLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRTDFQEG 376
           HL  DG+    G   +   ATPGHT+  + Y+       F GDT+ +   G  R DF  G
Sbjct: 120 HLFKDGETFPLGQFTVTVLATPGHTSDSVCYVVDGN--VFVGDTVFMPDSGTARCDFPGG 177

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQ-----TATSVAEEKKYNPRLTK--SLAEF 535
           ++  LY S+ +RIF L DE  LY  HDY+ Q       T+V E+KKYN  L    S  +F
Sbjct: 178 DASELYHSI-SRIFDLGDEITLYMCHDYQPQGRELYWKTTVGEQKKYNVHLKNHTSQHDF 236

Query: 536 VEI--MDNLNLPYPKMINKA 589
           V+I    +  L  PK++  A
Sbjct: 237 VKIRTQRDATLAVPKLLYPA 256


>UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Rep:
           Beta-lactamase-like - Desulfitobacterium hafniense
           (strain DCB-2)
          Length = 205

 Score = 72.5 bits (170), Expect = 7e-12
 Identities = 41/106 (38%), Positives = 59/106 (55%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           AD  L DG +++ G+  L   ATPGHT G + ++  E  L+  GDTL     GRTDF  G
Sbjct: 105 ADFLLEDGQILQVGNLNLTVIATPGHTLGGVCFLTSEGLLS--GDTLFDGSIGRTDFPGG 162

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           + + L KSV  ++  LP++  +YP H       T++  EK+ NP L
Sbjct: 163 SYDELIKSVVKKLLVLPEDTKVYPGHG----PETTIGREKRENPFL 204


>UniRef50_A3IFE3 Cluster: YqgX; n=1; Bacillus sp. B14905|Rep: YqgX -
           Bacillus sp. B14905
          Length = 214

 Score = 72.5 bits (170), Expect = 7e-12
 Identities = 33/87 (37%), Positives = 52/87 (59%)
 Frame = +2

Query: 254 AAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDE 433
           A  TPGH+ G ++Y+      A  GDTL  +G GRTD   G+++ L  S+H+++ TLP++
Sbjct: 129 AVFTPGHSPGSISYVFENDGFAIVGDTLFEQGVGRTDLIGGSTKILLASIHDKLLTLPED 188

Query: 434 YVLYPAHDYRGQTATSVAEEKKYNPRL 514
            ++YP H       T+V+ E + NP L
Sbjct: 189 TIIYPGHG----NYTTVSAEMETNPFL 211


>UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of
           metallo-beta-lactamase superfamily; n=1; Clostridium
           acetobutylicum|Rep: Predicted Zn-dependent hydrolase of
           metallo-beta-lactamase superfamily - Clostridium
           acetobutylicum
          Length = 199

 Score = 72.1 bits (169), Expect = 9e-12
 Identities = 39/109 (35%), Positives = 60/109 (55%)
 Frame = +2

Query: 182 DSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRT 361
           D    A  ++ DGD ++FG  ++    TPGHT G + Y+    +  F+GDTL     GRT
Sbjct: 95  DKSENATKYVDDGDELQFGELKIKCIKTPGHTPGGMCYLV--DNYLFSGDTLFNSSIGRT 152

Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           DF  G+  TL  S+ +++  L +  V+YP H   G+  T++  EK +NP
Sbjct: 153 DFPGGDFSTLINSIKSKLMKLDENIVVYPGH---GE-GTTIGYEKIHNP 197


>UniRef50_A3ZW37 Cluster: Putative uncharacterized protein; n=1;
           Blastopirellula marina DSM 3645|Rep: Putative
           uncharacterized protein - Blastopirellula marina DSM
           3645
          Length = 107

 Score = 72.1 bits (169), Expect = 9e-12
 Identities = 33/102 (32%), Positives = 57/102 (55%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           +G ++     +L     PGH++G + ++ H+  +   GD L     GRTDF +G+   L 
Sbjct: 4   EGAVLDLAGIQLEVRDAPGHSSGHVVFVIHDAQVVLGGDVLFAGSIGRTDFFDGDFGALR 63

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTK 520
            ++H+++FTLP E+++YP H       T++AEE   NP + K
Sbjct: 64  DAIHDKLFTLPGEFIVYPGHG----PETTIAEEIAENPFVGK 101


>UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2;
           Bacteria|Rep: Beta-lactamase domain protein -
           Desulfotomaculum reducens MI-1
          Length = 205

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 38/104 (36%), Positives = 59/104 (56%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           AD  L+DGD ++ G+  L    TPGHT G +     +    F+GDTL  +  GR+DF  G
Sbjct: 106 ADRLLVDGDTIQIGNITLEVLHTPGHTPGGICLKAGKD--LFSGDTLFAQSIGRSDFPGG 163

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           +  TL  S+ +++  L DE  +YP H      A+++ +EK++NP
Sbjct: 164 SHSTLIGSIKSKLLVLSDETKVYPGHG----PASTIGQEKRHNP 203


>UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein;
           n=1; Beggiatoa sp. PS|Rep: Metallo-beta-lactamase family
           protein - Beggiatoa sp. PS
          Length = 229

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
 Frame = +2

Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKS 400
           D ++ G  ++    TPGHT G   Y      +  TGDTL I GCGR DF     E +Y S
Sbjct: 107 DTIQLGKTDIEIWHTPGHTPGSACYYLDGHLI--TGDTLFIFGCGRCDFSGSEPEQMYHS 164

Query: 401 VHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL-TKSLAEFV 538
           +      LP E +++P H Y  Q ++++AE+ + NP +   ++A+FV
Sbjct: 165 LKKIGTELPKETIIHPGHHYAHQPSSTLAEQLEGNPFMHFNNIADFV 211


>UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3;
           Clostridiales|Rep: Putative uncharacterized protein -
           Ruminococcus torques ATCC 27756
          Length = 207

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 33/82 (40%), Positives = 46/82 (56%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGHT G   Y   E+ + F+GDTL     GRTD   G+   L +SV  ++  LP++  +
Sbjct: 128 TPGHTEGGCCYYIGEEHVLFSGDTLFHNSIGRTDLPTGSGSELVRSVREKLLVLPEDTRV 187

Query: 443 YPAHDYRGQTATSVAEEKKYNP 508
           YP H       T+++ EKKYNP
Sbjct: 188 YPGH----MEETTISHEKKYNP 205


>UniRef50_Q0W1G4 Cluster: Putative metallo-beta-lactamase; n=1;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           metallo-beta-lactamase - Uncultured methanogenic
           archaeon RC-I
          Length = 460

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 44/130 (33%), Positives = 60/130 (46%), Gaps = 19/130 (14%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS------LAFTGDTLLIRGCGRTDFQ 370
           L DGD + F    +L   TPGHT   LTY+ ++Q         FTGD L +   GR D  
Sbjct: 91  LRDGDRITFDKLSILTMETPGHTPESLTYVLYDQKYPDEPLATFTGDALFVNSTGRIDLP 150

Query: 371 EGNSE-----TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAE--------EKKYNPR 511
           + N +      LY S+H +I  L D  V+YPAH       + + +        EK+ NP 
Sbjct: 151 DENEKHVNAGKLYDSIHGKILPLGDHVVIYPAHGAGSVCGSGMGDRDWSTIGYEKRTNPH 210

Query: 512 LTKSLAEFVE 541
           L     EF+E
Sbjct: 211 LQLGRDEFIE 220


>UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10;
           Bacillaceae|Rep: Uncharacterized protein yqgX - Bacillus
           subtilis
          Length = 211

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLLDGD-LVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334
           G+  + G +  A+   HL++GD  +  G   L    TPGH+ G ++Y   +  L  +GD 
Sbjct: 91  GSGMLRGIEVTAKPADHLIEGDGELNIGPFHLETLFTPGHSPGSVSYYVKDADLVISGDV 150

Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           L   G GRTD   GN ETL  S+H ++ TLP+  ++   H       T V  E+  NP L
Sbjct: 151 LFQGGIGRTDLIGGNQETLLTSIHEKLLTLPEHTLVLSGHG----PETDVLTEQDQNPFL 206


>UniRef50_Q9JXH3 Cluster: Glyoxalase II family protein; n=5;
           Proteobacteria|Rep: Glyoxalase II family protein -
           Neisseria meningitidis serogroup B
          Length = 210

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 34/100 (34%), Positives = 49/100 (49%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L +G+ +  G +       PGHT G + + C E  L   GD L     GRTDF  GN   
Sbjct: 113 LEEGETLTVGRYAFQVLHIPGHTPGHIVFYCAEAELLIAGDVLFYETIGRTDFPRGNHAD 172

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           L  ++ N++FTLP+   +   H       TS+  EK++NP
Sbjct: 173 LINNIRNKLFTLPETVQVVAGHG----RMTSIGHEKRHNP 208


>UniRef50_Q39KM6 Cluster: Beta-lactamase-like; n=36;
           Proteobacteria|Rep: Beta-lactamase-like - Burkholderia
           sp. (strain 383) (Burkholderia cepacia (strain ATCC
           17760/ NCIB 9086 / R18194))
          Length = 241

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 37/105 (35%), Positives = 52/105 (49%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           + D  L DGD V+FG   L     PGHT G + +      +A  GD L     GRTDF  
Sbjct: 133 EPDHWLSDGDTVQFGDETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGRTDFPR 192

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           GN E L +S+  +++ L D+    P H   G  +T   +E++ NP
Sbjct: 193 GNHEDLVRSIKEKLWPLGDDVTFVPGH---GPVST-FGDERRTNP 233


>UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1;
           Clostridium thermocellum ATCC 27405|Rep:
           Beta-lactamase-like protein - Clostridium thermocellum
           (strain ATCC 27405 / DSM 1237)
          Length = 201

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 38/103 (36%), Positives = 56/103 (54%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           AD  L DG+++  G  +     TPGH+ G +     +  + FTGDTL   G GRTDF +G
Sbjct: 104 ADRLLKDGEVITVGGLDFEIIHTPGHSAGGICIKVGD--VVFTGDTLFCMGIGRTDFPDG 161

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
           +  TL  S+ N++  L D  V+YP H   G+  T   E K+++
Sbjct: 162 DLSTLLDSIKNKLMKLDDNVVVYPGH---GEPTTIGRERKEFS 201


>UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Beta-lactamase
           domain protein - Victivallis vadensis ATCC BAA-548
          Length = 205

 Score = 69.3 bits (162), Expect = 6e-11
 Identities = 44/117 (37%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L DG L+ FG   + A  TPGHT   + Y   + S  FTGD L + GC         S+ 
Sbjct: 93  LRDGQLLPFGETAVEAIFTPGHTRDSVCYRFADDSAVFTGDVLFV-GC----IGFCRSKE 147

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEFVEIMDNL 556
           +Y S+  +I  L D  V+Y  HDY      ++ EEKK NP L   SL EF   + +L
Sbjct: 148 MYNSLMKKILPLADSLVVYSGHDYGPVPFRTLGEEKKLNPYLNCHSLEEFKAELQHL 204


>UniRef50_Q54EJ5 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione
           hydrolase - Dictyostelium discoideum AX4
          Length = 292

 Score = 69.3 bits (162), Expect = 6e-11
 Identities = 44/128 (34%), Positives = 70/128 (54%), Gaps = 9/128 (7%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIR--GCGRT 361
           G+Q D    D +    GS ++   +TPGHT  C++Y     S+ F GDT+ +   G  R 
Sbjct: 120 GSQFDKLFTDDERFTIGSLQVRVISTPGHTPACVSYYIENDSV-FVGDTMFMPDVGTARC 178

Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY----RGQT-ATSVAEEKKYNPRLTKSL 526
           DF  G++ETL+ S+  +I  LP+   +Y  HDY    RG T  T++AE++  N  +  S+
Sbjct: 179 DFPNGSAETLWTSM-KKILELPETVKVYVCHDYPPQERGITFFTTIAEQRLSNKHIKDSV 237

Query: 527 A--EFVEI 544
              EF+++
Sbjct: 238 TKDEFIKM 245


>UniRef50_A1ID45 Cluster: Beta-lactamase-like; n=3; Bacteria|Rep:
           Beta-lactamase-like - Candidatus Desulfococcus
           oleovorans Hxd3
          Length = 210

 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 35/112 (31%), Positives = 61/112 (54%)
 Frame = +2

Query: 173 IGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGC 352
           I  ++    D  + +GD++ FG+ E+    TPGH+ G ++ +  ++  AF GDTL     
Sbjct: 100 IAAENSPPPDRTVKEGDVISFGTIEMKVLHTPGHSPGGISLVTDKK--AFVGDTLFAGSI 157

Query: 353 GRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           GRTDF  G+ +TL  ++  ++F L D+  +Y  H       T++  E++ NP
Sbjct: 158 GRTDFPGGDFDTLISAIQTKLFPLGDDVTVYCGHG----PETTIGMERRTNP 205


>UniRef50_Q39ZZ6 Cluster: Metallo-beta-lactamase family protein;
           n=1; Pelobacter carbinolicus DSM 2380|Rep:
           Metallo-beta-lactamase family protein - Pelobacter
           carbinolicus (strain DSM 2380 / Gra Bd 1)
          Length = 207

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 37/105 (35%), Positives = 54/105 (51%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L DGD++  G   +    TPGHT   +T   H      TGDTL +   GR D    +
Sbjct: 92  DRSLADGDVLTVGDTAVEIVHTPGHTPADITL--HLPGALLTGDTLFVTKVGRADMAGSD 149

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
              LY S+  R+   P E +++P HDY  Q  +++A E+++NP L
Sbjct: 150 PAALYASLR-RLAAFPGETLVFPGHDYGPQPHSTIAFERQHNPYL 193


>UniRef50_A5FR77 Cluster: Beta-lactamase domain protein; n=3;
           Dehalococcoides|Rep: Beta-lactamase domain protein -
           Dehalococcoides sp. BAV1
          Length = 217

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 35/103 (33%), Positives = 58/103 (56%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           DI L +G  +  G  +    + PGHT G +    + +   F+GDTL   G GR+DF+E +
Sbjct: 119 DIPLSEGSTLELGKIKFSVISIPGHTPGGICL--YTRGYLFSGDTLFNSGIGRSDFEESD 176

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           +E L +++ NR+ +LP E +++P H       T++ +EK  NP
Sbjct: 177 TEALRQNIINRLLSLPPETLVFPGHG----RETTIGKEKTGNP 215


>UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Beta-lactamase-like -
           Clostridium cellulolyticum H10
          Length = 208

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 40/113 (35%), Positives = 64/113 (56%), Gaps = 2/113 (1%)
 Frame = +2

Query: 176 GKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHE-QSLAFTGDTLLIRG 349
           GK S  ++   +L +G+ ++ G  +     TPGHT G    IC + ++L F+GDTL   G
Sbjct: 96  GKASTFKSKYEILREGNSIKVGELDFKIIHTPGHTCGS---ICIQVENLLFSGDTLFKFG 152

Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            GR D   GN   +Y S+  ++F LP E ++YP H   G+ +T++ +E + NP
Sbjct: 153 YGRVDLPNGNFSDIYNSIVEKLFILPGETIVYPGH---GE-STTITDEIRSNP 201


>UniRef50_Q9PFB0 Cluster: Beta-lactamase hydrolase-like protein;
           n=42; Proteobacteria|Rep: Beta-lactamase hydrolase-like
           protein - Xylella fastidiosa
          Length = 431

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 48/142 (33%), Positives = 73/142 (51%), Gaps = 10/142 (7%)
 Frame = +2

Query: 185 SGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGR 358
           +G+Q D    DGD+   GS +     +PGHT   +TY+  +   AF  DT+ +   G  R
Sbjct: 257 NGSQWDHLFADGDVFNVGSIKGRVMFSPGHTLASVTYVIGD--TAFVHDTIFMPDAGTAR 314

Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYR-----GQTATSVAEEKKYNPRLT-K 520
            DF  G++  L+ S+   I +LPDE  L+  HDY+      +  ++V E+KK NP L   
Sbjct: 315 ADFPGGSARALWSSIQT-ILSLPDETRLFTGHDYQPSGRHPRWESTVGEQKKANPHLAGV 373

Query: 521 SLAEFVEIMD--NLNLPYPKMI 580
               FV + +  +  LP PK+I
Sbjct: 374 DETTFVALREARDKTLPMPKLI 395


>UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=4; cellular organisms|Rep:
           Hydroxyacylglutathione hydrolase, putative - Caulobacter
           crescentus (Caulobacter vibrioides)
          Length = 249

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 38/95 (40%), Positives = 51/95 (53%)
 Frame = +2

Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370
           A  D  + DG+ V  G   L    T GHT G ++Y   E ++AF GDTL   GCGR    
Sbjct: 86  APLDRVVRDGEEVMLGDTRLTVIDTGGHTLGHVSYYDAEDAIAFVGDTLFALGCGR--LF 143

Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTA 475
           EG +E ++ S+  R+  LPDE  +Y AH+Y    A
Sbjct: 144 EGTAEQMWDSL-GRLIALPDETTVYCAHEYTASNA 177


>UniRef50_Q8EQ13 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 207

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334
           G+  +IG+   A  AD  + +G L   G   +    TPGH+ G ++YI  +Q +  +GD 
Sbjct: 91  GSHKLIGESILATPADFSVDEGGLT-IGEFSMQVYHTPGHSPGSVSYIFPDQKIVISGDV 149

Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           L  RG GRTD   G+   L  S+  +++ LP EY +   H       T++ EEK  NP
Sbjct: 150 LFQRGIGRTDLPGGDLAILEHSIREKLYQLPGEYQVLSGHG----GITTIKEEKNENP 203


>UniRef50_Q81LX4 Cluster: Metallo-beta-lactamase family protein;
           n=14; Bacillus|Rep: Metallo-beta-lactamase family
           protein - Bacillus anthracis
          Length = 208

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
 Frame = +2

Query: 206 HLLDGD-LVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382
           H++D +  +  GS       TPGH+ G ++Y C E S  F+GD L     GRTD   G+ 
Sbjct: 108 HIIDAEGTLAIGSFNFEIFETPGHSPGSISYYCKEASAVFSGDVLFQMSIGRTDLPGGSF 167

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
             L  S+  ++F LPDE  +   H       TS+  EK+ NP L
Sbjct: 168 AELIGSIEEKLFVLPDETAVLCGHG----PETSIGFEKENNPFL 207


>UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1;
           Pseudoalteromonas atlantica T6c|Rep: Beta-lactamase-like
           - Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 288

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 45/135 (33%), Positives = 74/135 (54%), Gaps = 11/135 (8%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRTDFQEGNS 382
           L DG+ ++FGS  L+  +TPGHT+  L+YI  +    F GDTL +   G  R DF  G++
Sbjct: 124 LQDGESLQFGSATLVCMSTPGHTSDSLSYIIDDN--VFVGDTLFMPDGGTARCDFPGGDA 181

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRG-----QTATSVAEEKKYNPRLTKSL--AEFVE 541
             L+ S+ NR+  LP  Y ++  HDY+      Q  T+VA+ +  N  +   +  A++V 
Sbjct: 182 GLLWDSI-NRLHHLPAHYKIWVCHDYQPDNRELQYQTTVAQSQAANIHVNNQIDKAQYVA 240

Query: 542 IMD--NLNLPYPKMI 580
           + +  +  L  PK++
Sbjct: 241 LRNKRDATLAVPKLL 255


>UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Beta-lactamase-like
           protein - Lentisphaera araneosa HTCC2155
          Length = 213

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 38/108 (35%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
 Frame = +2

Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNG--CLTYICHEQSLAFTGDTLLIRGCGRTD 364
           A  D  + D     FG  +L A  TPGH+ G  C      ++ L F+GDTL  RG GRTD
Sbjct: 106 ANVDHFIEDSQSFEFGEFKLEAIHTPGHSAGSTCFKIENSDEQLLFSGDTLFRRGVGRTD 165

Query: 365 FQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
              G+S  + KS+  +++ L  +  + P H       T + EEK+ NP
Sbjct: 166 LPSGDSREIAKSIKEKLYKLDIDTTVIPGHG----PNTVIGEEKRQNP 209


>UniRef50_Q1AWY9 Cluster: Beta-lactamase-like protein; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           Beta-lactamase-like protein - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 214

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 36/105 (34%), Positives = 52/105 (49%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D ++ D + V  G   L A  TPGH  G L +    +    +GD L     GRTD   G+
Sbjct: 107 DGYIEDRERVEVGGLTLEALYTPGHAPGHLAFYLESEGALLSGDALFAGSVGRTDLPGGD 166

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           +  L +S+  R+  LPDE V++P H       T++  E+ YNP L
Sbjct: 167 AGLLMRSIKERMLVLPDETVVHPGHG----PQTTIGNERAYNPFL 207


>UniRef50_Q11FA6 Cluster: Beta-lactamase-like; n=121;
           Proteobacteria|Rep: Beta-lactamase-like - Mesorhizobium
           sp. (strain BNC1)
          Length = 312

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 37/94 (39%), Positives = 51/94 (54%), Gaps = 2/94 (2%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361
           G+Q D    DGD    G+ ++     PGHT  CL Y+  +    F GDTL +   G  R 
Sbjct: 142 GSQFDHLFNDGDRFTIGNLDVTVLHVPGHTPACLAYVVGD--AVFPGDTLFMPDYGTARC 199

Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYR 463
           DF  G++  LY+S+  R+F LPDE  L+  HDY+
Sbjct: 200 DFPGGDARQLYRSI-KRLFQLPDEARLFLCHDYK 232


>UniRef50_A6PMC1 Cluster: Beta-lactamase domain protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Beta-lactamase
           domain protein - Victivallis vadensis ATCC BAA-548
          Length = 201

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 33/81 (40%), Positives = 44/81 (54%)
 Frame = +2

Query: 266 PGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLY 445
           PGHT G   ++  E    F GDT+     GRTDF  G+  T+  S+ N I TLPDE  +Y
Sbjct: 122 PGHTPGGSGFLFRESPALFAGDTIFAGSIGRTDFPGGDFGTIIDSIRNGILTLPDELTIY 181

Query: 446 PAHDYRGQTATSVAEEKKYNP 508
           P H     + T+V  E++ NP
Sbjct: 182 PGHG----SQTTVGAERRSNP 198


>UniRef50_A2FLV6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=2; Trichomonas vaginalis G3|Rep:
           Metallo-beta-lactamase superfamily protein - Trichomonas
           vaginalis G3
          Length = 223

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 32/82 (39%), Positives = 46/82 (56%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGHT G       ++ L F+GDTL     GR+DF  G+   L   + N +  LPD+ V+
Sbjct: 138 TPGHTPGGACLYNKQEKLLFSGDTLFKDSIGRSDFPYGDGRQLVSGIVNNLMKLPDDTVV 197

Query: 443 YPAHDYRGQTATSVAEEKKYNP 508
           +P H      +T++ EE+KYNP
Sbjct: 198 FPGHG----DSTTIGEERKYNP 215


>UniRef50_Q1MQL8 Cluster: Zn-dependent hydrolases, including
           glyoxylases; n=1; Lawsonia intracellularis
           PHE/MN1-00|Rep: Zn-dependent hydrolases, including
           glyoxylases - Lawsonia intracellularis (strain
           PHE/MN1-00)
          Length = 208

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 34/82 (41%), Positives = 44/82 (53%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGHT G +     E +  FTGDTL     GRTD    N+  L+ S+H +IF LP   ++
Sbjct: 129 TPGHTPGGVCLYFKEMNTLFTGDTLFYHTVGRTDLPGSNTNDLFTSLHKKIFVLPKYTIV 188

Query: 443 YPAHDYRGQTATSVAEEKKYNP 508
           YP H  +    TS+ EE   NP
Sbjct: 189 YPGHGPK----TSIEEELTNNP 206


>UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1;
           Acinetobacter baumannii ATCC 17978|Rep: Putative
           uncharacterized protein - Acinetobacter baumannii
           (strain ATCC 17978 / NCDC KC 755)
          Length = 186

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 37/105 (35%), Positives = 52/105 (49%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           + D  L  G++++ G  E      PGHT G + +      L +TGD L     GRTDF  
Sbjct: 79  KVDQWLEGGEVLKLGEDEFEVRFAPGHTPGHVMFYNKNHGLLWTGDVLFKGSIGRTDFPR 138

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           GN E L +S+    F+LPDE      H   G  +T +  EK++NP
Sbjct: 139 GNHEQLIESIQRECFSLPDETQFISGH---GPMST-IGYEKQFNP 179


>UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep:
           Glyoxalase II - Oryza sativa (Rice)
          Length = 336

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 35/87 (40%), Positives = 47/87 (54%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           DI L +GD   F  H++L   TPGHT+G + Y        FTGDTL    CG+    EG 
Sbjct: 170 DITLSEGDTWMFAGHQVLVMETPGHTSGHVCYHFPGSGAIFTGDTLFSLSCGK--LFEGT 227

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDY 460
            + +Y S+  +I  LPDE  +Y  H+Y
Sbjct: 228 PQQMYSSL-QKIIALPDETRVYCGHEY 253


>UniRef50_Q5XD24 Cluster: Uncharacterized protein M6_Spy0554; n=45;
           Bacilli|Rep: Uncharacterized protein M6_Spy0554 -
           Streptococcus pyogenes serotype M6
          Length = 232

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 245 ELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTL 424
           E     TPGH+ G ++++ H   L  TGD L     GRTD    N E L   +   +FTL
Sbjct: 146 EFTVLPTPGHSWGGVSFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTL 205

Query: 425 PDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           P+ Y +YP H      +T++  EK  NP
Sbjct: 206 PNHYRVYPGHG----PSTTICHEKNANP 229


>UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 207

 Score = 66.9 bits (156), Expect = 3e-10
 Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           +AD  L DG  +      +   ATPGHT G   Y   +  + F+GDTL     GRTDF  
Sbjct: 107 EADEFLKDGQKITLAGINMTFIATPGHTPGSGCYYLEDNEILFSGDTLFHGSRGRTDFPG 166

Query: 374 GNSETLYKSVHNRIF-TLPDEYVLYPAHDYRGQTATSVAEEKKY 502
           G+   + KS+  ++   LPDE  + P H+     +T++  EK Y
Sbjct: 167 GSESEIMKSIREKLLKKLPDETAVLPGHN----DSTTIGTEKVY 206


>UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase
           family; n=6; Proteobacteria|Rep: Zn-dependent
           hydrolases, glyoxylase family - Idiomarina loihiensis
          Length = 292

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 41/114 (35%), Positives = 60/114 (52%), Gaps = 7/114 (6%)
 Frame = +2

Query: 185 SGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIR--GCGR 358
           +G   D  L DG+    GS  +    TPGHT   + Y+ +E  + F GDTL     G  R
Sbjct: 121 NGEHFDKLLQDGETFHLGSMTIRVIHTPGHTPADIAYVINENKV-FVGDTLFNPDVGTAR 179

Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY-----RGQTATSVAEEKKYN 505
            DF  G++ TLY+S+  ++F L D   +Y  HDY     + Q  T+VA++K+ N
Sbjct: 180 CDFPGGSANTLYRSI-QKLFELEDTTEVYICHDYPPEERQHQCKTTVADQKQNN 232


>UniRef50_Q3A304 Cluster: Putative uncharacterized protein; n=1;
           Pelobacter carbinolicus DSM 2380|Rep: Putative
           uncharacterized protein - Pelobacter carbinolicus
           (strain DSM 2380 / Gra Bd 1)
          Length = 213

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 38/102 (37%), Positives = 49/102 (48%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L DGD +  GS  L     PGH+ G +   C E    F GD L     GRTD   G+   
Sbjct: 114 LQDGDRIEVGSIVLEVLHVPGHSPGSVCLKCGEA--LFAGDVLFAGSIGRTDLPGGDHHL 171

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           L K + +R+ TL D   +YP H      AT++  E+K NP L
Sbjct: 172 LLKGLQSRVLTLADSVKVYPGHG----PATTIGHERKNNPYL 209


>UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Rep:
           Beta-lactamase-like - Moorella thermoacetica (strain
           ATCC 39073)
          Length = 207

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 40/114 (35%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
 Frame = +2

Query: 179 KDSGAQADIHLLDGDLVRFGSHELLAAA-TPGHTNGCLTYICHEQSLAFTGDTLLIRGCG 355
           +++   AD  L + D +  G    L    TPGHT G +    H + L FTGDTL     G
Sbjct: 100 REASPPADRLLEEDDTIAIGKTVTLRVIHTPGHTPGGICL--HGEGLVFTGDTLFAGSIG 157

Query: 356 RTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517
           RTDF  G+   L  S+  ++FTL D   +YP H      A+++  E+  NP  T
Sbjct: 158 RTDFPGGSYSQLISSIKEKLFTLDDALEVYPGHG----PASTIGAERVDNPFFT 207


>UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 226

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 1/111 (0%)
 Frame = +2

Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382
           + + DG+ V  G   + A   PGHT GC+ +   E     TGD L +  CG   +   + 
Sbjct: 105 VPVADGEDVAIGDGRMRAVYAPGHTPGCVCWYGPEAKALITGDVLFVGSCGGVSYPGSDP 164

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATS-VAEEKKYNPRLTKSLAE 532
             +  ++  ++ +LP+E  +YP HDY G+T TS +  E   NP L     E
Sbjct: 165 AAMVHTLQRKLGSLPEETRVYPGHDY-GKTPTSTLMWEFVNNPALLADTLE 214


>UniRef50_A3I369 Cluster: Metallo-beta-lactamase family protein;
           n=2; Flexibacteraceae|Rep: Metallo-beta-lactamase family
           protein - Algoriphagus sp. PR1
          Length = 236

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 33/107 (30%), Positives = 52/107 (48%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDF 367
           G++    L +G+ +  G  +L     PGH  G + +   +      GDTL     GRTD 
Sbjct: 126 GSEPSGFLEEGEFISVGKEKLKVLFVPGHAPGHVVFYHSDSKQLIAGDTLFRGSIGRTDL 185

Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
             GN E L + + + +F LPD+ V++P H       T++  EK +NP
Sbjct: 186 PGGNHELLLQKIKSELFNLPDQTVVFPGHG----PETNIGFEKVHNP 228


>UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21;
           Actinomycetales|Rep: Beta-lactamase domain protein -
           Mycobacterium sp. (strain KMS)
          Length = 238

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 32/96 (33%), Positives = 55/96 (57%)
 Frame = +2

Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397
           GD+V  G  ++    TPGHT G   ++   + +A  GDTL + GCGRTDF  GN + +++
Sbjct: 129 GDVVSVGGIDIELLHTPGHTPGSQCFLLDGRLVA--GDTLFLEGCGRTDFPGGNVDDMFR 186

Query: 398 SVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
           S+   +  LP +  ++P H Y  + + +++  K+ N
Sbjct: 187 SL-QALAQLPGDPTVFPGHWYSAEPSDALSNVKRSN 221


>UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5;
           Bacteria|Rep: Hydroxyacylglutathione hydrolase -
           Dinoroseobacter shibae DFL 12
          Length = 256

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 37/113 (32%), Positives = 53/113 (46%)
 Frame = +2

Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370
           A  D    DGD   F  HE+    TPGHT   + +    + + FTGDTL + GCGR    
Sbjct: 88  AGVDTRYGDGDRFDFSGHEVRVIHTPGHTIDMINFYLPAEGVVFTGDTLFVMGCGR--LF 145

Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLA 529
           EG+   ++ S+  ++  LP + V+Y +H+Y    A         NP L    A
Sbjct: 146 EGDGPMMHASL-QKLAALPADTVIYCSHEYTEANADFALTVDPENPDLKDKAA 197


>UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2;
           Clostridiaceae|Rep: Beta-lactamase domain protein -
           Alkaliphilus metalliredigens QYMF
          Length = 206

 Score = 65.7 bits (153), Expect = 8e-10
 Identities = 34/103 (33%), Positives = 56/103 (54%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+ L DG+++  G+ +L    TPGH+ G +      + + FTGDTL     GR+D + GN
Sbjct: 107 DVFLKDGEVLTIGNLKLHVLHTPGHSPGGVCI--RGEGVVFTGDTLFANSIGRSDLEGGN 164

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            + L  S+ +++ TL DE  + P H      A+++  E+  NP
Sbjct: 165 YDQLIASIQSKLMTLDDELTVLPGHG----PASTIGIERMTNP 203


>UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1;
           Alkaliphilus metalliredigens QYMF|Rep: Beta-lactamase
           domain protein - Alkaliphilus metalliredigens QYMF
          Length = 207

 Score = 65.7 bits (153), Expect = 8e-10
 Identities = 31/98 (31%), Positives = 49/98 (50%)
 Frame = +2

Query: 161 TKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLL 340
           +K    K+     D+ L  GD +  G+ +L    TPGHT G +     ++ + FTGDT+ 
Sbjct: 94  SKREYAKEVSITPDVLLSHGDTISVGALQLEVIHTPGHTPGSICLAVKDEKVIFTGDTVF 153

Query: 341 IRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAH 454
               GRTD   G+   L K++ N++    D+  +YP H
Sbjct: 154 SDALGRTDLAGGSEAMLRKTIRNKVSKWDDDVRVYPGH 191


>UniRef50_A0Z233 Cluster: Putative uncharacterized protein; n=3;
           Proteobacteria|Rep: Putative uncharacterized protein -
           marine gamma proteobacterium HTCC2080
          Length = 308

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 39/113 (34%), Positives = 58/113 (51%), Gaps = 7/113 (6%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361
           G+Q D    DGD    G+    A   PGHT  C+ Y+ ++    F GDTL +   G  R 
Sbjct: 115 GSQFDQIFADGDSFYLGNITCAAMHVPGHTPACMAYLLND--ALFVGDTLFMPDAGTARC 172

Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQT-----ATSVAEEKKYN 505
           DF  GN+  L++S+  R+ TLP +  ++  HDY+         T+VAE++  N
Sbjct: 173 DFPGGNAHALFQSI-QRLLTLPGDTRIFVCHDYQPNDRPLAYETTVAEQRTLN 224


>UniRef50_A0HF94 Cluster: Beta-lactamase-like; n=6; cellular
           organisms|Rep: Beta-lactamase-like - Comamonas
           testosteroni KF-1
          Length = 249

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 35/100 (35%), Positives = 48/100 (48%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L DGD V  G   L     PGHT G + +   +   AF GD L     GRTDF +GN + 
Sbjct: 149 LHDGDTVTIGQETLNVRHCPGHTPGHVVFHSPQIDRAFVGDVLFAGSIGRTDFPQGNHQQ 208

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           L  S+  R++ + D+ +  P H       +S   E+K NP
Sbjct: 209 LIDSIVQRLWPMGDQTIFIPGHG----PESSFGRERKLNP 244


>UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=10; Chlorobiaceae|Rep:
           Hydroxyacylglutathione hydrolase, putative - Chlorobium
           tepidum
          Length = 215

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 1/133 (0%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTL 337
           G + ++  D  A+  I ++ G     G   +    TPGHT   +  +  +    FTGDTL
Sbjct: 75  GIRVLLFGDRDARLGIEVMHGASFPLGEGVVEIIHTPGHTLDSICLLAGDA--LFTGDTL 132

Query: 338 LIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517
            +   G T + E ++   Y+S+H R+  LP    ++P HDY     +++  EK  NP L 
Sbjct: 133 FVGKVGGT-WSEADARLEYRSLHERLMVLPAGTNVFPGHDYGTAPVSTIGHEKTTNPFLL 191

Query: 518 KSLAE-FVEIMDN 553
           +  AE F+++ +N
Sbjct: 192 QPDAESFIDLKNN 204


>UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=19; Bacteria|Rep: Hydroxyacylglutathione
           hydrolase, putative - Brucella suis
          Length = 257

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 39/129 (30%), Positives = 57/129 (44%)
 Frame = +2

Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397
           GD   FG  ++   +TPGHT G ++Y   +  + FTGDTL   GCGR    EG   T++ 
Sbjct: 98  GDEFTFGLFKVKVISTPGHTAGGISYYLPDAKVVFTGDTLFALGCGR--LFEGTPATMFH 155

Query: 398 SVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLPYPKM 577
           S+  ++  LP +  LY  H+Y    A         N  L +   E   +  +  +  P  
Sbjct: 156 SL-EKLVALPGDTALYCGHEYTQNNARFALTIDPDNSALKERAKEIARLRAHERMTLPST 214

Query: 578 INKAGAGEP 604
           I    A  P
Sbjct: 215 IALEMATNP 223


>UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658;
           n=15; Actinomycetales|Rep: Uncharacterized protein
           Rv2581c/MT2658 - Mycobacterium tuberculosis
          Length = 224

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 5/105 (4%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYIC-----HEQSLAFTGDTLLIRGCGRTDFQEGN 379
           DGD +  G   +    TPGHT G + +       +++ + FTGDTL  R  GRTD   G+
Sbjct: 119 DGDKIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGS 178

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
              L +S+ +++  L D  V+ P H      +T++  E+++NP L
Sbjct: 179 GRDLLRSIVDKLLVLDDSTVVLPGHG----NSTTIGAERRFNPFL 219


>UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25;
           Euteleostomi|Rep: Probable hydrolase PNKD - Homo sapiens
           (Human)
          Length = 385

 Score = 64.1 bits (149), Expect(2) = 2e-09
 Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 5/85 (5%)
 Frame = +2

Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQ-----SLAFTGDTLLIRGCGRTDFQEGNSE 385
           D+V  G  ++ A ATPGHT G L Y+   +     S  F+GD L + GCGRT   EGN+E
Sbjct: 212 DVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRT--FEGNAE 269

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDY 460
           T+  S+ + +  L D+ +L+P H+Y
Sbjct: 270 TMLSSL-DTVLGLGDDTLLWPGHEY 293



 Score = 20.6 bits (41), Expect(2) = 2e-09
 Identities = 7/18 (38%), Positives = 12/18 (66%)
 Frame = +2

Query: 461 RGQTATSVAEEKKYNPRL 514
           +G   +++ EE+ YNP L
Sbjct: 326 KGTCPSTLGEERSYNPFL 343


>UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Rep:
           Isoform 3 of Q8N490 - Homo sapiens (Human)
          Length = 361

 Score = 64.1 bits (149), Expect(2) = 2e-09
 Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 5/85 (5%)
 Frame = +2

Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQ-----SLAFTGDTLLIRGCGRTDFQEGNSE 385
           D+V  G  ++ A ATPGHT G L Y+   +     S  F+GD L + GCGRT   EGN+E
Sbjct: 188 DVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRT--FEGNAE 245

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDY 460
           T+  S+ + +  L D+ +L+P H+Y
Sbjct: 246 TMLSSL-DTVLGLGDDTLLWPGHEY 269



 Score = 20.6 bits (41), Expect(2) = 2e-09
 Identities = 7/18 (38%), Positives = 12/18 (66%)
 Frame = +2

Query: 461 RGQTATSVAEEKKYNPRL 514
           +G   +++ EE+ YNP L
Sbjct: 302 KGTCPSTLGEERSYNPFL 319


>UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Pseudomonadales|Rep: Hydroxyacylglutathione hydrolase -
           Pseudomonas mendocina ymp
          Length = 257

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 42/135 (31%), Positives = 60/135 (44%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+ L D DL+          A PGHT G + Y   EQ+L   GDTL   GCGR    EG 
Sbjct: 88  DVDLGDNDLIEVLGLRFQIMAVPGHTLGHIAYYHAEQNLLLCGDTLFAGGCGR--LFEGT 145

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLN 559
            + +++S+ +R+  LP    +Y  H+Y           + +NP ++  LAE     D   
Sbjct: 146 PQQMHQSL-SRLAALPGATRVYCTHEYTLSNLRFAHAVEPHNPDVSARLAEVSRWRDEGR 204

Query: 560 LPYPKMINKAGAGEP 604
           +  P  I    A  P
Sbjct: 205 ISLPSSIELELATNP 219


>UniRef50_A7HGC5 Cluster: Beta-lactamase domain protein; n=2;
           Anaeromyxobacter|Rep: Beta-lactamase domain protein -
           Anaeromyxobacter sp. Fw109-5
          Length = 217

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 36/103 (34%), Positives = 51/103 (49%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D H  DG+  R G+ E     TPGH+ G +     ++ L F+GDTL     GRTD   G+
Sbjct: 107 DHHPGDGESFRVGASEGRVIHTPGHSPGSICLFFPQERLLFSGDTLFAGSVGRTDLPGGD 166

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            + L+ S+  ++F L D+    P H   G     V EE+  NP
Sbjct: 167 FDALHASITGKLFPLGDDVRFLPGHGPAG----VVGEERLSNP 205


>UniRef50_A2DJY1 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Trichomonas vaginalis G3|Rep:
           Metallo-beta-lactamase superfamily protein - Trichomonas
           vaginalis G3
          Length = 248

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 37/112 (33%), Positives = 58/112 (51%)
 Frame = +2

Query: 227 VRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVH 406
           +  G   L    TPGHT G ++Y   E      GDT+     G T+   GN + L  S+ 
Sbjct: 128 IDIGGDRLHIIETPGHTPGSISYYYPEGKWVVVGDTVFAGLIGSTNHYGGNKKQLVNSII 187

Query: 407 NRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNL 562
           ++I TLPD+ V+YP H   G+ +T V +EKK NP++ +   +    +D + +
Sbjct: 188 SKILTLPDDTVIYPGH---GKNST-VKDEKK-NPQIIQFFKKNPPTIDQIKV 234


>UniRef50_Q41FV9 Cluster: Beta-lactamase-like; n=1; Exiguobacterium
           sibiricum 255-15|Rep: Beta-lactamase-like -
           Exiguobacterium sibiricum 255-15
          Length = 205

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 32/100 (32%), Positives = 52/100 (52%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L+ G L   G  +     TPGH+ G +T+   ++ +AF GD +  R  GRTD + G+ + 
Sbjct: 109 LVSGSL-EIGPFQFHVLETPGHSPGSVTFYFKKEQVAFAGDLIFKRSVGRTDLEGGDQDV 167

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           L +S+   I  +P +   YP H       T++ +E K+NP
Sbjct: 168 LMRSIDRVIAEIPHDTTFYPGHG----PETTLRQEIKHNP 203


>UniRef50_A7IG57 Cluster: Beta-lactamase domain protein; n=1;
           Xanthobacter autotrophicus Py2|Rep: Beta-lactamase
           domain protein - Xanthobacter sp. (strain Py2)
          Length = 235

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 36/107 (33%), Positives = 51/107 (47%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D +L +G+ V  G   L     PGHT G L ++     +A  GDTL     GRTDF  G+
Sbjct: 133 DRYLSEGETVSVGDLTLDILHVPGHTPGHLVFVHKGVGIAIVGDTLFRGSVGRTDFPYGD 192

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTK 520
            + L   +  ++  L D  V  P H       TS+ +EK +NP L +
Sbjct: 193 PDLLIAGIVGKLLPLGDNVVCLPGHG----PVTSIGDEKAHNPFLPR 235


>UniRef50_A7CUG8 Cluster: Beta-lactamase domain protein; n=1;
           Opitutaceae bacterium TAV2|Rep: Beta-lactamase domain
           protein - Opitutaceae bacterium TAV2
          Length = 236

 Score = 63.3 bits (147), Expect = 4e-09
 Identities = 36/103 (34%), Positives = 51/103 (49%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  +  GD +R    E      PGH  G + +       AF GD L     GRTD   G+
Sbjct: 134 DAVVTQGDRLRAFGIEAEVRHVPGHCPGNVLFYFAPMGAAFVGDALFAGSVGRTDLPGGS 193

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           SE L +SV  +I+TLP+E  ++P H       T+V +E++ NP
Sbjct: 194 SEQLARSVRTQIYTLPNETQVFPGHG----GPTTVGKERESNP 232


>UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2;
           Sulfolobus|Rep: Putative uncharacterized protein -
           Sulfolobus solfataricus
          Length = 209

 Score = 63.3 bits (147), Expect = 4e-09
 Identities = 39/104 (37%), Positives = 51/104 (49%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           +GD +  G  +L    TPGHT G +  I +     FTGDTL     GRTD   G SE L 
Sbjct: 112 EGDEIELGGEKLKIIETPGHTMGSICIIAN--GYIFTGDTLFYGTVGRTDL--GGSEKLL 167

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSL 526
           +    ++  LPDE ++YP H       T +  EK  NP LT  +
Sbjct: 168 RESLEKLKKLPDEIIVYPGHG----PFTVLGYEKVKNPFLTMDI 207


>UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Gluconobacter oxydans|Rep: Hydroxyacylglutathione
           hydrolase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 259

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 34/112 (30%), Positives = 54/112 (48%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           DGD +  GS ++   +TPGH  G ++Y+  E    F GD L   GCGR    EG ++ L+
Sbjct: 113 DGDSLSLGSAQIRVLSTPGHAVGHVSYVVPEVPALFCGDVLFSLGCGR--LLEGTAQELF 170

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMD 550
            S+H R  +LPD+ ++   H+Y              N  L     E  ++++
Sbjct: 171 DSLH-RYDSLPDQTLVCAGHEYTRSNLAFALHVDPDNAALKARAGEIEQLLE 221


>UniRef50_Q47LT8 Cluster: Putative hydrolase; n=1; Thermobifida
           fusca YX|Rep: Putative hydrolase - Thermobifida fusca
           (strain YX)
          Length = 209

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 34/87 (39%), Positives = 48/87 (55%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           + D  LLDG++++ G+ EL    TPG+T G +       +  FTGDTLL  G    ++  
Sbjct: 110 EPDAPLLDGEVLQIGAVELEVRHTPGYTPGSVCLYVPALATVFTGDTLLGHGAS-GEYAP 168

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAH 454
            + ETL  SV  R+FTLP E  +Y  H
Sbjct: 169 DDPETLRTSVAGRLFTLPPETTVYSGH 195


>UniRef50_Q5FRS6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Gluconobacter oxydans|Rep:
           Metallo-beta-lactamase superfamily protein -
           Gluconobacter oxydans (Gluconobacter suboxydans)
          Length = 245

 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 32/99 (32%), Positives = 50/99 (50%)
 Frame = +2

Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397
           G+++     +L  A  PGHT G + ++ H+      GDTL     GRTDF  G+S+ L  
Sbjct: 149 GEVLHLLGQDLHVAHVPGHTPGHVVFVDHDNRRVLAGDTLFRGTVGRTDFAYGDSQALVD 208

Query: 398 SVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
            +   + TL D+ V+   H       T++ EE++ NP L
Sbjct: 209 GIRRHLLTLSDDTVVLCGHG----MPTTIGEERRTNPFL 243


>UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium
           difficile|Rep: Putative hydrolase - Clostridium
           difficile (strain 630)
          Length = 204

 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 38/104 (36%), Positives = 54/104 (51%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           ADI++ D D +  G  ++    TPGHT GC+     ++   FTGDTL     GRTD   G
Sbjct: 106 ADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDE--MFTGDTLFAGSIGRTDLYSG 163

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           +   + KS+  ++    D   +YP H   G T+T +  EKK NP
Sbjct: 164 DFNQMEKSL-KKLCKYEDAVRVYPGH---GPTST-LGVEKKTNP 202


>UniRef50_A4XI82 Cluster: Beta-lactamase domain protein; n=1;
           Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
           Beta-lactamase domain protein - Caldicellulosiruptor
           saccharolyticus (strain ATCC 43494 / DSM 8903)
          Length = 199

 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 29/95 (30%), Positives = 49/95 (51%)
 Frame = +2

Query: 170 VIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRG 349
           ++G +     D +  DGD++ FG        TPGHT G   ++ +   + F+GDTL    
Sbjct: 93  IVGCEVTINCDEYFKDGDVLEFGDLNFKVIHTPGHTPGSSCFL-YGGDILFSGDTLFKDS 151

Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAH 454
            GR D   G+ + +++S+ N++ TL     +YP H
Sbjct: 152 YGRCDLPLGDEKQIFESIKNKLLTLSKSTKVYPGH 186


>UniRef50_A1ZPC4 Cluster: Metallo-beta-lactamase family protein;
           n=1; Microscilla marina ATCC 23134|Rep:
           Metallo-beta-lactamase family protein - Microscilla
           marina ATCC 23134
          Length = 217

 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 30/103 (29%), Positives = 49/103 (47%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+ + + D + FG+  L     PGH  G + ++   Q     GD L     GRTDF   +
Sbjct: 111 DVFVSEEDTIEFGNSSLEILFVPGHAPGHIAFLNRAQKFVINGDVLFKGSVGRTDFPGCS 170

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            E L  S+  +++ L D+  +Y  H       T++  EK++NP
Sbjct: 171 HEDLVNSIRTKMYALDDDVTVYTGHG----PETTIGYEKQFNP 209


>UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n=1;
           unknown|Rep: UPI00015BCB57 UniRef100 entry - unknown
          Length = 217

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 40/122 (32%), Positives = 57/122 (46%)
 Frame = +2

Query: 149 LVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTG 328
           L PG    +   +  + D ++ DGD +   S ++    TPGHT G   +    Q+    G
Sbjct: 96  LFPGFSIYLNAKTPPKPDFYIKDGDKLSIASVDIEIIHTPGHTPGGCCFYLPSQNTLIAG 155

Query: 329 DTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
           DTL   G GRTD   G+ E L KS+      LP +  +   H Y+    TS+  E K+NP
Sbjct: 156 DTLFKGGVGRTDLPGGSWEDLSKSLKKIFSILPKDTHVICGH-YQD---TSLEHELKFNP 211

Query: 509 RL 514
            L
Sbjct: 212 FL 213


>UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrolase
           (Glyoxalase II) (GLX II) protein; n=1; alpha
           proteobacterium HTCC2255|Rep: Putative
           hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX
           II) protein - alpha proteobacterium HTCC2255
          Length = 255

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 36/135 (26%), Positives = 61/135 (45%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           +I +  GD++  G+ +     TPGHT G ++Y   +    FTGD+L+  GCGR    EG 
Sbjct: 90  NISVSTGDVISIGNQQAEILNTPGHTIGHISYFFKDSKKVFTGDSLMSLGCGR--LFEGT 147

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLN 559
            + ++ ++      LP E ++Y  H+Y    A         N RL +   E  +++ +  
Sbjct: 148 HKMMWNTL-KLFMKLPKETLVYSGHEYSYSNAKFALSVDSSNTRLKEYYKEIQDLLKDNK 206

Query: 560 LPYPKMINKAGAGEP 604
              P  +    A  P
Sbjct: 207 YTVPTSLELEFAINP 221


>UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20;
           Ascomycota|Rep: Function: RSP29 precursor - Aspergillus
           niger
          Length = 299

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSH-ELLAAATPGHTNGCLTYICHE--QSLAFTG 328
           G  SVIG  +          G++ + G    + A  TP HT   + Y   +    + FTG
Sbjct: 122 GQLSVIGGKNCQSVTKTPAHGEVFKIGERISVKALHTPCHTQDSICYFMQDGDDKVVFTG 181

Query: 329 DTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
           DTL I GCGR  F EG +  ++K+++  +  LPD+  +YP H+Y
Sbjct: 182 DTLFIGGCGR--FFEGTAPEMHKALNETLAALPDDTKVYPGHEY 223


>UniRef50_Q7R4U1 Cluster: GLP_440_31929_31255; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_440_31929_31255 - Giardia lamblia
           ATCC 50803
          Length = 224

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 27/66 (40%), Positives = 38/66 (57%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGHT G     C++  + FTGDT+     GRTDF  G+S+ L  SV      L D++ +
Sbjct: 141 TPGHTPGSSLLYCNKAKVVFTGDTIFANSVGRTDFPGGSSKQLKASVKRIYKELSDDFRI 200

Query: 443 YPAHDY 460
           YP H++
Sbjct: 201 YPGHNH 206


>UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Schizosaccharomyces pombe|Rep: Hydroxyacylglutathione
           hydrolase - Schizosaccharomyces pombe (Fission yeast)
          Length = 256

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
 Frame = +2

Query: 140 LKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS-- 313
           LK   P      G D    + + L D + +R G+ ++ A  TP HT   + +  H  +  
Sbjct: 75  LKKEFPHVTIYGGSDQNGVSHV-LQDKETLRIGNVQIEALHTPCHTRDSICFYAHSSNEH 133

Query: 314 LAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
             FTGDTL   GCGR  F EG +  ++ +++  + +LP+  V+YP H+Y
Sbjct: 134 AVFTGDTLFNAGCGR--FFEGTAAEMHIALNAVLSSLPNNTVIYPGHEY 180


>UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein;
           n=9; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Methylococcus capsulatus
          Length = 256

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 32/87 (36%), Positives = 49/87 (56%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+ L DG+  R GS        PGHT+G + +   + +  F GDTL   GCGR    EG+
Sbjct: 89  DVALKDGEEFRLGSASARMLDVPGHTSGHVAFWFEDDAALFCGDTLFALGCGR--LFEGS 146

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDY 460
           +E +++S+  R+  LP E  ++ AH+Y
Sbjct: 147 AEQMWRSL-ERLRALPAETKVFCAHEY 172


>UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Psychrobacter|Rep: Hydroxyacylglutathione hydrolase -
           Psychrobacter sp. PRwf-1
          Length = 259

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 38/112 (33%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
 Frame = +2

Query: 131 LGKLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQ 310
           + +L+ L P T  V   + G + D  + +G  V    +     A PGHT   L Y+  ++
Sbjct: 65  VAELRELYPMTHVVASAEHGVKPDQVVKEGSSVSAWGYTAQVWAVPGHTQSHLAYVLDKE 124

Query: 311 --SLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
                F GDTL   GCGR     G  E L+ S   R   LPD  + YPAH+Y
Sbjct: 125 GHKQVFCGDTLFSAGCGRV--FTGTIEQLHDS-FKRFNKLPDNTLFYPAHEY 173


>UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione
           hydrolase - Dictyostelium discoideum AX4
          Length = 268

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 7/105 (6%)
 Frame = +2

Query: 167 SVIGKDSGAQADIHLLDG-DLVRFGSHELLAAATPGHTNGCLTYICHEQS------LAFT 325
           +V G+D   +     L+  ++++ GS ++     P HT+  + Y+  +++        FT
Sbjct: 76  NVYGRDERFEGITKKLENNEVLKIGSLKIKTLDAPAHTSSHVLYLIEDENEPNQVKSLFT 135

Query: 326 GDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
           GDTL I GCGR    EGN E +Y +++N I  LPD  ++Y  H+Y
Sbjct: 136 GDTLFIGGCGR--LFEGNPEQMYNALYNVIGKLPDNTLVYVGHEY 178


>UniRef50_Q3IR18 Cluster: Homolog 4 to thiosulfate
           sulfurtransferase/ hydrolase (Probable
           hydroxyacylglutathione hydrolase) 2; n=1; Natronomonas
           pharaonis DSM 2160|Rep: Homolog 4 to thiosulfate
           sulfurtransferase/ hydrolase (Probable
           hydroxyacylglutathione hydrolase) 2 - Natronomonas
           pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 388

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG---- 376
           L   ++V  G  +L A  TPGHT+G  +Y+  E +L  TGDT+ +   GRT+ Q G    
Sbjct: 217 LARNEVVTVGDVDLKAVFTPGHTSGMASYLVDENAL-LTGDTVFVDSVGRTELQFGAADA 275

Query: 377 --NSETLYKSVHNRIFTLPDEYVLYPAHDYRG 466
              ++ LY+S+H  I   PD   + P H + G
Sbjct: 276 DTGAKLLYESLHGTILAEPDSVTVLPGHFHVG 307


>UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;
           Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Mus
           musculus (Mouse)
          Length = 260

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
 Frame = +2

Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLLDG-DLVRFGSHELLAAATPGHTNGCLTYICH--- 304
           KL  L PG K V G D    A  H +     ++ GS  +   +TP HT+G + Y      
Sbjct: 65  KLVKLEPGLK-VYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPG 123

Query: 305 --EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
             E S  FTGDTL + GCG+  F EG ++ +YK++   +  LP +  +Y  H+Y
Sbjct: 124 SSEPSAVFTGDTLFVAGCGK--FYEGTADEMYKALLEVLGRLPPDTKVYCGHEY 175


>UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=11;
           Proteobacteria|Rep: Metallo-beta-lactamase superfamily -
           Nitrosomonas europaea
          Length = 262

 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 44/121 (36%), Positives = 59/121 (48%), Gaps = 2/121 (1%)
 Frame = +2

Query: 209 LLDGDLVRFG--SHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382
           L +GD + F   S EL     PGHT G +   CH Q+  F GDTL   GCGR    EGN+
Sbjct: 88  LAEGDTLVFPELSLELSILDVPGHTAGHIA--CHGQNRLFCGDTLFACGCGR--IFEGNA 143

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNL 562
           + ++ S+  ++  LPDE  +Y AH+Y              NP L + L   VE     N+
Sbjct: 144 QQMFDSL-QKLTDLPDETQVYCAHEYTLDNIRFARAIDPDNPELIE-LESNVEEKREQNM 201

Query: 563 P 565
           P
Sbjct: 202 P 202


>UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Acinetobacter sp. ADP1|Rep: Putative
           hydroxyacylglutathione hydrolase - Acinetobacter sp.
           (strain ADP1)
          Length = 244

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 38/117 (32%), Positives = 51/117 (43%)
 Frame = +2

Query: 230 RFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHN 409
           +F    +   ATPGHT G + Y   E    F GDTL   GCGR    EG+ E +Y S+ N
Sbjct: 103 KFNHLNVEVLATPGHTLGHVVYFIEETGSLFCGDTLFAMGCGRV--FEGSFEQMYHSL-N 159

Query: 410 RIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLPYPKMI 580
           R+  LP    +Y  H+Y    A      +  N  L + L E   +     +  P  I
Sbjct: 160 RLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALKERLKEVQSLRSRHQITLPSTI 216


>UniRef50_Q2S0T9 Cluster: Metallo-beta-lactamase family protein;
           n=1; Salinibacter ruber DSM 13855|Rep:
           Metallo-beta-lactamase family protein - Salinibacter
           ruber (strain DSM 13855)
          Length = 216

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
 Frame = +2

Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTD-FQEGNS 382
           HL +GD V FG   L    TPGH+   ++++      A TGD L     GRT    E + 
Sbjct: 111 HLAEGDTVSFGDVTLEVLHTPGHSPDSISFVDRPGRQALTGDVLFQNSIGRTQGLPETSR 170

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSL 526
             L  SV   +  L D+  +YP H      AT++  E+  NP + ++L
Sbjct: 171 AQLLNSVTETLLPLGDDVTIYPGHG----PATTIGRERAQNPFVQEAL 214


>UniRef50_A2DXP6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Trichomonas vaginalis G3|Rep:
           Metallo-beta-lactamase superfamily protein - Trichomonas
           vaginalis G3
          Length = 222

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 31/101 (30%), Positives = 51/101 (50%)
 Frame = +2

Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385
           ++  GD V  G +      TPG + G + YI  ++ + FTG T++    G T F  G++ 
Sbjct: 114 NIASGDEVSAGKYHFRVMETPGISPGSVIYILDDEEIVFTGMTIMKGIVGPTCFPYGDAG 173

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            LY S+  RI  LP  + +YP +  +    + ++EE   NP
Sbjct: 174 KLYTSIKERILVLPKNFAIYPGYGPK----SKISEEASTNP 210


>UniRef50_Q2SAD4 Cluster: Zn-dependent Hydrolase, including
           glyoxylases; n=5; Gammaproteobacteria|Rep: Zn-dependent
           Hydrolase, including glyoxylases - Hahella chejuensis
           (strain KCTC 2396)
          Length = 210

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 37/103 (35%), Positives = 50/103 (48%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L +GD V  G   L     PGHT G + +      LA  GD L     GRTDF +G+
Sbjct: 108 DRWLNEGDEVSVGEETLQVLHCPGHTPGHVIFFHQGARLALVGDVLFNGSIGRTDFPKGD 167

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
             TL +S+  +++ L D+    P H   G  +T  A E+K NP
Sbjct: 168 HATLIQSIKTKLWPLGDDVSFIPGH---GPMSTFGA-ERKTNP 206


>UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase,
           putative, expressed; n=3; Oryza sativa|Rep:
           Hydroxyacylglutathione hydrolase, putative, expressed -
           Oryza sativa subsp. japonica (Rice)
          Length = 258

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 45/149 (30%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
 Frame = +2

Query: 137 KLKSLVPGTKSVIGK-DSGAQADIHLLDGDLVRFGSH-ELLAAATPGHTNGCLTYIC--- 301
           K+   VPG K   G  D+       + +G  +  G   E+L   TP HT G ++Y     
Sbjct: 65  KMAQSVPGIKVYGGSLDNVKGCTDQVENGTKLSLGKDIEILCLHTPCHTKGHISYYVTSK 124

Query: 302 -HEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTAT 478
             E    FTGDTL I GCGR  F EG +E +Y+S+   + +LP    +Y  H+Y  +   
Sbjct: 125 EEEDPAVFTGDTLFIAGCGR--FFEGTAEQMYQSLCVTLGSLPKPTQVYCGHEYTVKNLK 182

Query: 479 SVAEEKKYNPRLTKSLAEFVEIMDNLNLP 565
            +   +  N ++ + L E+ +     N P
Sbjct: 183 FILTVEPDNEKVKQKL-EWAQKQREANQP 210


>UniRef50_Q1IW29 Cluster: Beta-lactamase-like protein; n=4;
           Deinococci|Rep: Beta-lactamase-like protein -
           Deinococcus geothermalis (strain DSM 11300)
          Length = 219

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICH---EQSLAFTGDTLLIRGCGRTDFQ 370
           D+ +  G     G   L A   PGH  G + ++     E      GDTL     GRTD  
Sbjct: 115 DVEIAQGQTFTAGDLRLTARELPGHAPGHVVFVAQSGEEPGFVVAGDTLFQGSIGRTDLP 174

Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
            GN   L   +   + +LPDE  +YP H      AT+V  E++ N
Sbjct: 175 GGNHPQLIAGIRRELLSLPDETAIYPGHG----PATTVGAERRTN 215


>UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1;
           Roseobacter sp. AzwK-3b|Rep: Beta-lactamase-like protein
           - Roseobacter sp. AzwK-3b
          Length = 306

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLL--IRGCGRTDFQEGNSET 388
           DGD  + G+ ++    +PGHT G +TY+  + + AF  DTL+    G  R DF  G+S  
Sbjct: 136 DGDTFKLGNLDVRVMLSPGHTLGSITYVVGDDA-AFVHDTLMHVDVGTSRADFPGGSSNE 194

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDY 460
           LY S+   I  LPD+  L+  HDY
Sbjct: 195 LYDSL-QAILALPDQTRLFIGHDY 217


>UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 260

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 36/105 (34%), Positives = 56/105 (53%), Gaps = 8/105 (7%)
 Frame = +2

Query: 170 VIGKDSGAQA-DIHLLDGDLVRFGSHELLAAATPGHTNGCLTY-ICH------EQSLAFT 325
           ++G DS   A D H+  GD+  F   ++   +TP HT+G + Y I +         + FT
Sbjct: 77  ILGGDSRIPAMDRHVKHGDMAEFAGLQIKCLSTPCHTSGHICYHITNPAADSTSPGVVFT 136

Query: 326 GDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
           GDTL I GCGR  F EG +  +  +++  +  LP E  ++P H+Y
Sbjct: 137 GDTLFIAGCGR--FFEGTAPQMDVALNEILKNLPVETQIFPGHEY 179


>UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;
           Ascomycota|Rep: Hydroxyacylglutathione hydrolase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 256

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS--LAFTGDTLLIRGCGRTDFQEGNSET 388
           D ++ + G  ++ A  TP HT   + Y     S    FTGDTL   GCGR  F EG+++ 
Sbjct: 99  DKEIFKVGEVQVEALHTPCHTQDSICYYVSSPSKRAVFTGDTLFTSGCGR--FFEGDAKQ 156

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEF 535
           +  ++++ +  LPD+ V YP H+Y    A   +      P LTK L +F
Sbjct: 157 MDYALNHVLAALPDDTVTYPGHEYTKSNA-KFSSTIFSTPELTK-LVDF 203


>UniRef50_O67893 Cluster: Uncharacterized protein aq_2135; n=1;
           Aquifex aeolicus|Rep: Uncharacterized protein aq_2135 -
           Aquifex aeolicus
          Length = 211

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 35/117 (29%), Positives = 53/117 (45%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTL 337
           G  S IG     + D+ + +GD++R G  E     TPGHT G       ++ +   GD L
Sbjct: 91  GFASYIGAVPCPEPDVEISEGDVIRVGDVEFKVLHTPGHTPGLCCLYEEKRRVLIAGDLL 150

Query: 338 LIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
                GR D   GN   L KSV   +  LP + ++   H       T++ +E+ +NP
Sbjct: 151 FKGSVGRWDLPGGNLVELKKSVKRVLTELPQDTLVICGH----YDETTIGQERAFNP 203


>UniRef50_A3CXZ9 Cluster: Beta-lactamase domain protein; n=1;
           Methanoculleus marisnigri JR1|Rep: Beta-lactamase domain
           protein - Methanoculleus marisnigri (strain ATCC 35101 /
           DSM 1498 / JR1)
          Length = 467

 Score = 58.8 bits (136), Expect = 9e-08
 Identities = 46/141 (32%), Positives = 67/141 (47%), Gaps = 19/141 (13%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLA------FTGDTLLIRGCGRTDF--- 367
           +G+    GS EL    TPGHT   ++ +  ++S++      FTGD L     GRTD    
Sbjct: 90  EGETFTVGSLELEILETPGHTIESISLLLRDRSVSGDPLMVFTGDALFAGDVGRTDLAGE 149

Query: 368 --QEGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRLT 517
             +   SE LY S+H +I  LPD  ++ PAH        +   +  T++  EK  N  L+
Sbjct: 150 DKRREMSEMLYASLHQKILPLPDSTIVCPAHGAGSVCGGNIGDREYTTIGFEKATNGLLS 209

Query: 518 KSLAEFVEIMDNLNLPYPKMI 580
            S  EFVE   +  L  P+ I
Sbjct: 210 LSKEEFVERKMSERLYEPQYI 230


>UniRef50_Q9HQ50 Cluster: Flavoprotein; n=4; Halobacteriaceae|Rep:
           Flavoprotein - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 192

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 38/112 (33%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
 Frame = +2

Query: 131 LGKLKSLVPG-TKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHE 307
           +G L +LV     +V+G D  A AD  L DGD +R G  + +   TPGH    +      
Sbjct: 59  VGNLDALVDAFDPTVLGFDGVADADRALADGDEIRLGDDDYVVLHTPGHEPHHVCLYSPA 118

Query: 308 QSLAFTGDTLLIRGC-GRTDFQEGNSETLYKSVHNRIFTLPDEYV--LYPAH 454
             + F+ D +   G  GRTD   G+ ETL +S+     T+  E +  LYP H
Sbjct: 119 AGVLFSADLVFANGSFGRTDLDGGDRETLVESIDRLADTVAGEELTALYPGH 170


>UniRef50_UPI000049880A Cluster: metallo-beta-lactamase superfamily
           protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           metallo-beta-lactamase superfamily protein - Entamoeba
           histolytica HM-1:IMSS
          Length = 217

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 31/102 (30%), Positives = 50/102 (49%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+ L  GD +    H+ +   TPGH+ G  ++   ++ +   GDTL     GRTD   G+
Sbjct: 115 DVILKGGDEINLDGHKGVVLHTPGHSPGSCSFYFKDEEIVINGDTLFAGSYGRTDLWGGS 174

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
              L  S+ N +F+LP   ++   H     + T++ E KK N
Sbjct: 175 FAQLKASIKNVLFSLPLNTIVVTGHG----SNTTIREAKKSN 212


>UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1;
           Fulvimarina pelagi HTCC2506|Rep: Putative
           uncharacterized protein - Fulvimarina pelagi HTCC2506
          Length = 289

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
 Frame = +2

Query: 233 FGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET--LYKSVH 406
           FGS  + A  TPGHT G ++Y     +  F+GDTL   GCG +D + G  ++  L++S+ 
Sbjct: 129 FGSIGIEALETPGHTAGSISY--RIGACLFSGDTLFSEGCGLSDPRNGGGDSGALFRSLD 186

Query: 407 NRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
               TLP E  +YP H YR     + A  ++ N
Sbjct: 187 ALRRTLPAECRIYPGHRYRQPIGRTFAALQRGN 219


>UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep:
           Glyoxylase 3 - Aedes aegypti (Yellowfever mosquito)
          Length = 302

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
 Frame = +2

Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICH--EQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           D +  G+ ++   +TP HT   + Y     E  + FTGDTL + GCGR  F EG  + +Y
Sbjct: 142 DTLEIGNLKVRCISTPCHTTSHICYYIETPEDKVVFTGDTLFLAGCGR--FFEGTPQQMY 199

Query: 395 KSVHNRIFTLPDEYVLYPAHDY 460
            ++  ++  LPD+  +Y  H+Y
Sbjct: 200 DALITKLSALPDDTKVYCGHEY 221


>UniRef50_Q5HP04 Cluster: Metallo-beta-lactamase family protein;
           n=18; Staphylococcus|Rep: Metallo-beta-lactamase family
           protein - Staphylococcus epidermidis (strain ATCC 35984
           / RP62A)
          Length = 207

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 26/64 (40%), Positives = 40/64 (62%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGH+ G L+++ ++   A  GDTL   G GRTD  +G+ ETL  S+ +++F L  +  L
Sbjct: 129 TPGHSPGSLSFVFND--FAVVGDTLFKNGIGRTDLYKGDYETLIDSIKDKLFELEGDMPL 186

Query: 443 YPAH 454
           +P H
Sbjct: 187 FPGH 190


>UniRef50_P75849 Cluster: Uncharacterized protein ycbL; n=120;
           Bacteria|Rep: Uncharacterized protein ycbL - Escherichia
           coli (strain K12)
          Length = 215

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 32/105 (30%), Positives = 51/105 (48%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L +GD +  G+  L     PGHT G + +      L  +GD +   G GR+DF  G+
Sbjct: 108 DRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGRSDFPRGD 167

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
              L  S+ +++  L D+ +  P H   G  +T +  E+ +NP L
Sbjct: 168 HNQLISSIKDKLLPLGDDVIFIPGH---GPLST-LGYERLHNPFL 208


>UniRef50_Q1D198 Cluster: Metallo-beta-lactamase family protein;
           n=1; Myxococcus xanthus DK 1622|Rep:
           Metallo-beta-lactamase family protein - Myxococcus
           xanthus (strain DK 1622)
          Length = 483

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 43/158 (27%), Positives = 77/158 (48%), Gaps = 22/158 (13%)
 Frame = +2

Query: 158 GTKSVIGKDS-GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYIC-----HEQSLA 319
           G + V G+      AD+ + + + +  G+  L+A  TPGHT   +++       H Q+  
Sbjct: 71  GAQVVAGRHPITGHADVRMGERERLHLGALTLVALHTPGHTPESMSWAVYLDPHHAQAWG 130

Query: 320 -FTGDTLLIRGCGRTDFQEG-----NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATS 481
            FTGD LL    GRTD         N+  L+ S+H ++  L D+ +++PAH       + 
Sbjct: 131 VFTGDALLAGETGRTDLAAPERVYENAALLFDSLHQKVLPLGDQTLVFPAHGAGSVCRSG 190

Query: 482 VAE--------EKKYNPRLTKSLAEFVE--IMDNLNLP 565
           +A+        E+ +NP  T S ++F++  + + L+ P
Sbjct: 191 IADRELTTLGFERLHNPVFTSSRSDFIQRKVQERLHRP 228


>UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,
           partial; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 268

 Score = 54.0 bits (124), Expect(2) = 4e-07
 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
 Frame = +2

Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQ- 310
           KLKSL        G+  G     H L DGD  + G  +  A  TPGHT G + Y+     
Sbjct: 65  KLKSLHSNLAVYGGERDGVPGCNHKLKDGDSFQIGGLKFTALFTPGHTVGHMVYLLDRSD 124

Query: 311 ----SLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
               +  FTGD L + G GR    EG    +  S+ ++I  +PD+ +++P H+Y
Sbjct: 125 KNLPNSLFTGDILFLGGNGR--MFEGPPSLMLSSL-DKICQIPDDTLVWPGHEY 175



 Score = 22.6 bits (46), Expect(2) = 4e-07
 Identities = 12/39 (30%), Positives = 20/39 (51%)
 Frame = +2

Query: 434 YVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMD 550
           YV     + R  + +++ EEK YNP L  S    ++ +D
Sbjct: 199 YVEERRKERRITSPSTLGEEKSYNPFLRTSQDSILQQVD 237


>UniRef50_Q9A911 Cluster: Glyoxalase II family protein; n=21;
           Proteobacteria|Rep: Glyoxalase II family protein -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 273

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 48/103 (46%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L DGD V  G  E      PGHT G + +   E   A  GD L     GRTDF  GN
Sbjct: 149 DRWLDDGDTVTLGETEFEVFHCPGHTPGHVVFFHRETKFAQVGDVLFQGSIGRTDFPMGN 208

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
            + L  S+  +++ L ++    P H   G  +T  A E++ NP
Sbjct: 209 HQDLIDSITQKLWPLGEDVRFVPGH---GPMSTFGA-ERRGNP 247


>UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16;
           Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium
           japonicum
          Length = 255

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 33/118 (27%), Positives = 53/118 (44%)
 Frame = +2

Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370
           A  D+ + + D+V+ G+       TPGHT   ++Y+   +   F  DTL   GCGR    
Sbjct: 87  ANVDLRVANADVVKVGNLLARVVETPGHTLDHISYVFDTEKTVFAADTLFSIGCGRV--F 144

Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEI 544
           EG    ++ S+  ++  LPD++ LY  H+Y              N  L    AE  ++
Sbjct: 145 EGTYPMMWDSL-LKLRALPDDFKLYCGHEYTASNVKFALTVDPDNAALQARAAEVAKL 201


>UniRef50_Q73JL5 Cluster: Metallo-beta-lactamase family protein;
           n=1; Treponema denticola|Rep: Metallo-beta-lactamase
           family protein - Treponema denticola
          Length = 213

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 32/82 (39%), Positives = 45/82 (54%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L DGD+V  G   L    TPGHT G + +   E  + F+GDTL  R  GRTD   G+ + 
Sbjct: 121 LKDGDIVN-GFKVLY---TPGHTEGSVCFWNEEAKVLFSGDTLFYRSHGRTDLLGGDDQK 176

Query: 389 LYKSVHNRIFTLPDEYVLYPAH 454
           +  S+ + +  LPD+  +YP H
Sbjct: 177 MKASLKS-LLNLPDDTTVYPGH 197


>UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including
           glyoxylase; n=2; Magnetospirillum|Rep: Zn-dependent
           hydrolase, including glyoxylase - Magnetospirillum
           magneticum (strain AMB-1 / ATCC 700264)
          Length = 270

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 28/86 (32%), Positives = 46/86 (53%)
 Frame = +2

Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382
           + + +G+    G   +     PGHT+G + Y   +  + F GDTL   GCGR    EG +
Sbjct: 105 LEVSEGETFMLGHAAVTVLEVPGHTSGHVAYWLADSHVLFCGDTLFSLGCGR--LFEGTA 162

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDY 460
           E ++ S+  ++  LP + + YPAH+Y
Sbjct: 163 EEMWASL-KKLRDLPPDTLAYPAHEY 187


>UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9;
           Rhodobacterales|Rep: Hydroxyacylglutathione hydrolase -
           Silicibacter sp. (strain TM1040)
          Length = 271

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 35/132 (26%), Positives = 58/132 (43%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDF 367
           G   D+ L  G     G+      A PGHT G + +   E    F+ D+L++ GCGR   
Sbjct: 102 GVTLDMELEPGFEGGTGAGRCQVLAVPGHTLGHIAFYYPEAPALFSADSLMVMGCGR--L 159

Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIM 547
            EG    +++++   +  LPDE ++Y  H+Y    A      +  N  L K + E  +  
Sbjct: 160 FEGTPAMMWQTM-TTLSALPDETLIYSGHEYTESNAGFALSLEPENAALQKRMDEITKTR 218

Query: 548 DNLNLPYPKMIN 583
            N     P +++
Sbjct: 219 QNGQPTVPALLS 230


>UniRef50_A5WCY4 Cluster: Beta-lactamase domain protein; n=5;
           Proteobacteria|Rep: Beta-lactamase domain protein -
           Psychrobacter sp. PRwf-1
          Length = 295

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 42/131 (32%), Positives = 61/131 (46%), Gaps = 13/131 (9%)
 Frame = +2

Query: 179 KDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHE-----QSLA-FTGDTLL 340
           K   +Q D    +G     G  EL     PGHT   + YI        Q LA F GDTL 
Sbjct: 112 KTDASQFDKLTEEGTQFMLGDIELTVMHVPGHTPADMAYIAKNTADTTQPLAIFVGDTLF 171

Query: 341 IR--GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQ-----TATSVAEEKK 499
               G  R DF  G+ + LY+S+  +I  LP++ V+Y  HDY  Q       T+V  +K 
Sbjct: 172 APDVGTARVDFPGGDVDALYESIQ-KILALPEDTVIYLCHDYPPQDRTHSPVTTVGAQKA 230

Query: 500 YNPRLTKSLAE 532
           +N  + + +++
Sbjct: 231 HNIHVHQGISQ 241


>UniRef50_A3HIG2 Cluster: Beta-lactamase domain protein; n=18;
           Gammaproteobacteria|Rep: Beta-lactamase domain protein -
           Pseudomonas putida (strain GB-1)
          Length = 383

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 28/86 (32%), Positives = 45/86 (52%)
 Frame = +2

Query: 251 LAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPD 430
           +A  TPGHT G +++   +  L   GDTL  RG GRTD   G+   + +S+  R++ L +
Sbjct: 298 VALHTPGHTPGSMSFWFADAKLLIAGDTLFRRGIGRTDLWGGDQRAIVRSIKERLYRLDE 357

Query: 431 EYVLYPAHDYRGQTATSVAEEKKYNP 508
           E ++   H       T + +E + NP
Sbjct: 358 EAIVVTGHG----PDTRLGDEMRENP 379


>UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Methylobacterium extorquens PA1|Rep:
           Hydroxyacylglutathione hydrolase - Methylobacterium
           extorquens PA1
          Length = 158

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 28/66 (42%), Positives = 37/66 (56%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGH    +TY   +  + F+GDTL   GCGR    E   ETL++S+ +R   LPD   +
Sbjct: 13  TPGHCADHVTYYFADAGVVFSGDTLFTLGCGRV--MEAEPETLWRSL-SRFLDLPDATAV 69

Query: 443 YPAHDY 460
           Y  HDY
Sbjct: 70  YSGHDY 75


>UniRef50_Q8Y5A2 Cluster: Lmo2167 protein; n=12; Listeria|Rep:
           Lmo2167 protein - Listeria monocytogenes
          Length = 205

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 29/82 (35%), Positives = 42/82 (51%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGH+ G +++I  E      GD L     GRTD   G+ + L  S+  ++F LPD++  
Sbjct: 127 TPGHSIGSVSFIFDE--FVVVGDALFKGSIGRTDLYTGDFDMLINSIKTQLFVLPDDFPA 184

Query: 443 YPAHDYRGQTATSVAEEKKYNP 508
           Y  H       T++  EKK NP
Sbjct: 185 YSGHG----DVTTIGHEKKTNP 202


>UniRef50_Q5H3M1 Cluster: Beta-lactamase; n=8; Xanthomonadaceae|Rep:
           Beta-lactamase - Xanthomonas oryzae pv. oryzae
          Length = 296

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 11/145 (7%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361
           G+Q D    D +    G  E    A PGHT+  + Y+  +    F GD+L +   G  R 
Sbjct: 138 GSQFDHLFADDERFLIGRIEARVVAVPGHTSDSIAYLIGD--ALFPGDSLFMPDAGTARC 195

Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY-RGQTA----TSVAEEKKYNPRLTK-- 520
           DF  G++  L+ S+  R++ LPD   ++  HDY  G  A    TS+ E+++ N  +    
Sbjct: 196 DFPGGDARQLFASI-QRLYALPDSTRVFVCHDYGPGGRAVAHQTSIGEQRRSNIHVRDGV 254

Query: 521 SLAEFVEIMD--NLNLPYPKMINKA 589
            +  FV      + +LP PK+I  A
Sbjct: 255 DVETFVAQRQARDASLPEPKLIRPA 279


>UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1;
           Geobacter uraniumreducens Rf4|Rep: Beta-lactamase domain
           protein - Geobacter uraniumreducens Rf4
          Length = 233

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 29/95 (30%), Positives = 48/95 (50%)
 Frame = +2

Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKS 400
           D +R G   +    TPGHT G + Y+    SL FTGDT+ + GCG    + G++  +++S
Sbjct: 114 DQIRLGETLINCLLTPGHTTGSMCYLL-SHSL-FTGDTVFVEGCGICTTEGGSASGMFES 171

Query: 401 VHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
           +     T+     ++P H Y      S+A   ++N
Sbjct: 172 IQRIKRTVEPHVSVFPGHCYGRAPGCSLASVMEHN 206


>UniRef50_A1AVZ9 Cluster: Beta-lactamase domain protein; n=2;
           sulfur-oxidizing symbionts|Rep: Beta-lactamase domain
           protein - Ruthia magnifica subsp. Calyptogena magnifica
          Length = 240

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 4/123 (3%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           + D +  G+       TPGH+ G + Y+     +A  GDTL + G G      GN   L+
Sbjct: 108 NNDTIFIGNTPAKIINTPGHSAGGICYLLDGHIIA--GDTLFVYGAGHCSLPGGNINELF 165

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP-RLTKSLAEFVEIMDNL---NL 562
            S+  ++  + D  +L+  HDY  +  T++ E+K+ N   L  + A+F+  ++++    +
Sbjct: 166 HSMQ-KLKRIDDNVMLHCGHDYGSRVNTTMGEQKQGNAFLLIDNEADFLNYVNSMQQGKI 224

Query: 563 PYP 571
           PYP
Sbjct: 225 PYP 227


>UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep:
           Glyoxalase IIB - Plasmodium falciparum
          Length = 263

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 11/141 (7%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHE-----------QSLAFTGDTLLIRGCGRT 361
           DG ++R G   + A   P HT G + Y  ++           + + FTGDTL I GCGR 
Sbjct: 96  DGQIIRLGELNIKAIHAPCHTKGHILYYVYKTDEAKQEDHKYKPILFTGDTLFIAGCGR- 154

Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVE 541
            F EG+++ ++K++  ++  +  E ++Y  H+Y           +  N  +   L E  E
Sbjct: 155 -FFEGSAKDMFKNI-EKVKNMRKETLIYCGHEYTLNNLRFALSIENDNEYMKNKLNEVTE 212

Query: 542 IMDNLNLPYPKMINKAGAGEP 604
            + N     P  I +     P
Sbjct: 213 KLKNKEHSVPSTIEEENLINP 233


>UniRef50_UPI00006CD179 Cluster: metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 493

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 12/111 (10%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYIC---HEQSLAFT 325
           G K V G  + A  D HL  DG+ +  G   +    TPGHT     Y+      Q   FT
Sbjct: 101 GAKIVYGPTAKASFDFHLATDGEKIPIGKVNIEVLHTPGHTQESSCYLLLDGERQHAVFT 160

Query: 326 GDTLLIRGCGRTDFQEGNSET--------LYKSVHNRIFTLPDEYVLYPAH 454
           GDTL +   GR D    + E         +Y S+ N+I  L  + ++YP H
Sbjct: 161 GDTLFLGEVGRPDLAVKSGEITKEDLAGWMYDSLRNKIMKLDPKVIVYPGH 211


>UniRef50_Q1PVA8 Cluster: Similar to hydroxyacylglutathione
           hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
           Similar to hydroxyacylglutathione hydrolase - Candidatus
           Kuenenia stuttgartiensis
          Length = 189

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%)
 Frame = +2

Query: 164 KSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI 343
           KS  G+     A+  L   +++  G+ +  A +TPGHT   ++Y  +     FTGD L  
Sbjct: 79  KSYAGEGEVHSANNILQGSEIIEVGALQFKALSTPGHTLHGMSY--YIPGGVFTGDALFC 136

Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
              G T+  +   +   + +H  IFTLPDE +++PAH       T+V  EK  NP
Sbjct: 137 GSVGGTNSSKA-VQCQTEHIHKHIFTLPDETLVFPAHG----PMTTVGIEKYTNP 186


>UniRef50_A0LDZ9 Cluster: Beta-lactamase domain protein; n=1;
           Magnetococcus sp. MC-1|Rep: Beta-lactamase domain
           protein - Magnetococcus sp. (strain MC-1)
          Length = 209

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 37/107 (34%), Positives = 52/107 (48%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           + D  L  G  +     +L    TPGHT G +  I     +A  GDTL   G GRTD   
Sbjct: 107 EIDHPLTHGQRLELCGLQLEIIHTPGHTPGGVC-IRWGDEIA-VGDTLFAGGVGRTDLPG 164

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           G+ E L  S+  R+ TL D+ V +P H      +T++ +E+  NP L
Sbjct: 165 GDHEQLMHSIETRLMTLGDDVVCHPGHG----ASTTIGQERMGNPFL 207


>UniRef50_A2FNK4 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Trichomonas vaginalis G3|Rep:
           Metallo-beta-lactamase superfamily protein - Trichomonas
           vaginalis G3
          Length = 212

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
 Frame = +2

Query: 203 IHLLD-GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           +H ++  D ++FG         PGHT G L     + +L FTGDTL     G T F  GN
Sbjct: 100 LHYVEKNDTIQFGDELFYIHTLPGHTPGGLGLYSQKHNLIFTGDTLFKSARGSTSFIGGN 159

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKK 499
              + +S+++    +P    +YP H       T++A+E K
Sbjct: 160 YTDMMQSLYDLFTYIPGNATVYPGH----YATTTIADEMK 195


>UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase related;
           n=4; Thermococcaceae|Rep: Hydroxyacylglutathione
           hydrolase related - Pyrococcus abyssi
          Length = 222

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 25/70 (35%), Positives = 39/70 (55%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           + ++ L DGD ++ G  +L    TPGHT G       E+ + FTGDT+ +   GRTD   
Sbjct: 119 EVELKLEDGDEIKVGKVKLRLIHTPGHTRGSSCLYYEEERIMFTGDTVFLGTYGRTDLPT 178

Query: 374 GNSETLYKSV 403
           GN + + +S+
Sbjct: 179 GNEDKIVESL 188


>UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular
           organisms|Rep: Metallo-beta-lactamase - Methanosarcina
           acetivorans
          Length = 481

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 10/94 (10%)
 Frame = +2

Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS------LAFTGDTLLIRGCGRTD 364
           + L++GD        +    TPGHT   ++Y+  + S        F GDTL +   GR D
Sbjct: 87  VGLVEGDTFEIEDMTVKVLETPGHTPEHISYVVSDTSRGPDPTAVFCGDTLFVGDVGRPD 146

Query: 365 FQEGNSE----TLYKSVHNRIFTLPDEYVLYPAH 454
              G +     TLY S+H ++ +LPD   +YPAH
Sbjct: 147 LFPGKARELASTLYDSLHKKLLSLPDSCEVYPAH 180


>UniRef50_A0B5Y5 Cluster: Beta-lactamase domain protein; n=1;
           Methanosaeta thermophila PT|Rep: Beta-lactamase domain
           protein - Methanosaeta thermophila (strain DSM 6194 /
           PT) (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 214

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 1/88 (1%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRG-CGRTDFQ 370
           + D+ L DG ++  G   L    TPGH+ G + +    + + F+GDT+   G  GRTD  
Sbjct: 105 EVDMPLEDGMVLDLGDLRLEVIHTPGHSPGSMCFYERREGMLFSGDTVFPDGNIGRTDLF 164

Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAH 454
            G++E L +S+  R+  L D   +YP H
Sbjct: 165 GGSTEDLVRSI-ERLLELDDVSCMYPGH 191


>UniRef50_Q2LX15 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           cellular organisms|Rep: Hydroxyacylglutathione hydrolase
           - Syntrophus aciditrophicus (strain SB)
          Length = 485

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 17/117 (14%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS----LAFTGDTLLIRGCGRTDF----- 367
           DG   + G  +L A  +PGHT G ++Y+ ++      + FTGD L     GR DF     
Sbjct: 124 DGQTWKIGRLKLEAIHSPGHTPGSMSYLLYDADGNPWMVFTGDALFAGDVGRVDFLGEDR 183

Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRL 514
            +  +  LY ++H R+  L DE ++   H        D   +  T++  E++YNP+L
Sbjct: 184 MKKMAWLLYDTLHRRLLPLGDEVIVCAGHGAGSVCAGDISDRLWTTIGLERRYNPKL 240


>UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Babesia bovis|Rep: Hydroxyacylglutathione
           hydrolase, putative - Babesia bovis
          Length = 319

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 43/151 (28%), Positives = 72/151 (47%), Gaps = 8/151 (5%)
 Frame = +2

Query: 137 KLKSLVPGTKSVIGKDSGAQADIH--LLDGDLVRFGSHELLAAATPGHTNGCLTYICHE- 307
           ++  ++PG   V G ++   A +   ++DGD+VR G  E+     P HT G + Y     
Sbjct: 131 EMARIIPGIP-VYGSNNEDMAGMTNGIMDGDVVRLGGLEIKGVRVPCHTLGHMLYYVTNP 189

Query: 308 -----QSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQT 472
                Q L FTGDT+ I GCGR  F EG ++ +  ++ N +     + ++Y  H+Y  + 
Sbjct: 190 SDPTMQPLMFTGDTIFIGGCGR--FFEGTADMML-NIMNTVRQYRKDSLIYCGHEYTVKN 246

Query: 473 ATSVAEEKKYNPRLTKSLAEFVEIMDNLNLP 565
               A     +P + + + E+ E     NLP
Sbjct: 247 -LKFASTVDDSPAVKRKM-EWAESARQQNLP 275


>UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=40; Gammaproteobacteria|Rep: Probable
           hydroxyacylglutathione hydrolase - Escherichia coli
           O157:H7
          Length = 251

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 31/82 (37%), Positives = 44/82 (53%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           DG+      HE    ATPGHT G + Y    +   F GDTL   GCGR    EG +  +Y
Sbjct: 91  DGETAFVLGHEFSVIATPGHTLGHICYF--SKPYLFCGDTLFSGGCGR--LFEGTASQMY 146

Query: 395 KSVHNRIFTLPDEYVLYPAHDY 460
           +S+  ++  LPD+ ++  AH+Y
Sbjct: 147 QSL-KKLSALPDDTLVCCAHEY 167


>UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1,
           mitochondrial precursor; n=12; core eudicotyledons|Rep:
           Hydroxyacylglutathione hydrolase 1, mitochondrial
           precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 331

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 32/93 (34%), Positives = 45/93 (48%)
 Frame = +2

Query: 167 SVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIR 346
           S + KD     DI L D D   F  HE+    TPGHT G +++     +  FTGD +   
Sbjct: 154 SAVDKDRIPGIDILLKDSDKWMFAGHEVRILDTPGHTQGHISFYFPGSATIFTGDLIYSL 213

Query: 347 GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLY 445
            CG     EG  E +  S+  +I +LPD+  +Y
Sbjct: 214 SCG--TLSEGTPEQMLSSL-QKIVSLPDDTNIY 243


>UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 468

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 41/128 (32%), Positives = 63/128 (49%), Gaps = 20/128 (15%)
 Frame = +2

Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS-------LAFTGDTLLIRG 349
           A AD  + + D++ FGS  L    TPGHT   + +IC++++         F+GD L +  
Sbjct: 91  AYADHIVKEEDVLSFGSIRLKPLHTPGHTPEHIMWICYDETRSHDLPWFIFSGDCLFVGS 150

Query: 350 CGRTDFQEGN-----SETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAE 490
            GR D    N     ++ LY+S+  RI  LPD   ++PAH        +  G  AT++  
Sbjct: 151 VGRPDLLGENAFNFLAKELYQSLFVRIAHLPDSVEVFPAHGAGSLCGKNIGGVDATTLGY 210

Query: 491 EKKYNPRL 514
           E+  NP L
Sbjct: 211 ERTCNPYL 218


>UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=5; Sphingomonadaceae|Rep:
           Hydroxyacylglutathione hydrolase precursor -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 246

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 34/110 (30%), Positives = 49/110 (44%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+ +  GD VR G H       P HT G + Y   + +  F GDT+   GCGR    EG 
Sbjct: 95  DVLVKGGDTVRLGDHVADVWDVPAHTAGHIAYHFADDAAIFVGDTMFAMGCGR--LFEGT 152

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLA 529
           +E ++ ++  ++  L D   +Y AH+Y    A         N  L   LA
Sbjct: 153 AEQMFANM-QKLRALDDATRVYCAHEYTLSNARFAITVDPANEALAARLA 201


>UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           cellular organisms|Rep: Hydroxyacylglutathione hydrolase
           - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 263

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 35/99 (35%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 170 VIGKDSGAQADIHLLDGDLVRFGSH-ELLAAATPGHTNGCLTYICH-EQSLAFTGDTLLI 343
           + G D G +A      GD+++ G   EL    TPGHT   +    H EQ   F+GDTL  
Sbjct: 86  IAGVDRGVKA------GDVIKVGKTVELECLDTPGHTMCHICLRSHTEQPALFSGDTLFN 139

Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
            G G      G+   LY +   ++  LPD+ ++YP HDY
Sbjct: 140 AGAGNVH-NGGDVNALYATFAEQLARLPDDTLVYPGHDY 177


>UniRef50_Q01Q87 Cluster: Beta-lactamase domain protein; n=1;
           Solibacter usitatus Ellin6076|Rep: Beta-lactamase domain
           protein - Solibacter usitatus (strain Ellin6076)
          Length = 465

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 12/111 (10%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICH--EQS----L 316
           G    +G ++GA    + + DGD +RFG+  L    TPGHT   ++ +    E+S     
Sbjct: 71  GADIYLGAEAGAAFPHVPVRDGDELRFGNCVLRFLETPGHTLESISILVTDLERSPDPYA 130

Query: 317 AFTGDTLLIRGCGRTDFQEGNSET-----LYKSVHNRIFTLPDEYVLYPAH 454
             TGDTL I   GR D    ++       LY+S+  ++ TLPD   +YPAH
Sbjct: 131 VLTGDTLFIGDVGRPDLAPNHTPQQLAGMLYESLQKKLLTLPDGVEVYPAH 181


>UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 214

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 40/104 (38%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
 Frame = +2

Query: 206 HLLD-GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382
           HLLD GD V  G  EL   ATPGHT G   Y   E      GDTL     GRTDF   + 
Sbjct: 111 HLLDDGDTVTLGELELTFVATPGHTPGQGCY--WEGDDIIVGDTLFAGSVGRTDFPMSDP 168

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
                S+  R+F LP    ++  H       T++A E++ NP L
Sbjct: 169 SLARHSL-RRLFELPPHLRVHSGHG----PVTTLARERESNPFL 207


>UniRef50_Q8ZX02 Cluster: Conserved protein; n=4; Pyrobaculum|Rep:
           Conserved protein - Pyrobaculum aerophilum
          Length = 207

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 31/82 (37%), Positives = 43/82 (52%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGHT G ++ +       FTGD L  R  GRTD   G+ E L +SV  R++ LP  + +
Sbjct: 117 TPGHTPGSISLV--GDGFVFTGDALFYRSVGRTDLPYGDWEALVQSV-CRLYGLPPSFQV 173

Query: 443 YPAHDYRGQTATSVAEEKKYNP 508
           YP H       T++  E + NP
Sbjct: 174 YPGHG----PETTIGAEARGNP 191


>UniRef50_A3VUN8 Cluster: Hydrolase; n=5; Proteobacteria|Rep:
           Hydrolase - Parvularcula bermudensis HTCC2503
          Length = 451

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 18/118 (15%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSL------AFTGDTLLIRGCGRTDFQEG 376
           +GD    G   L    TPGHT   L+Y+ +++S        FTGD L I   GRTDF   
Sbjct: 92  EGDTFEIGGALLKVLETPGHTEDSLSYVLYDKSFEEGPVGVFTGDALFIGDVGRTDFYPD 151

Query: 377 NSE----TLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRL 514
                   LY S+  ++  L D+ ++YPAH            +  +S+  EK  NPRL
Sbjct: 152 RKREVAGLLYDSL-EKLLGLGDQCLVYPAHGAGSVCGSGMADREFSSIGHEKLNNPRL 208


>UniRef50_A0M126 Cluster: Metallo-beta-lactamase/rhodanese-like
           domain protein; n=7; Bacteria|Rep:
           Metallo-beta-lactamase/rhodanese-like domain protein -
           Gramella forsetii (strain KT0803)
          Length = 476

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 23/144 (15%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSL-----AFTGDTLLIRGCGRTDF---- 367
           +GD   FG  +++A  TPGHT   L+Y+ +E          TGD+L +   GR D     
Sbjct: 105 EGDEFEFGQVKMMAKHTPGHTPEHLSYLLYESHKEDPWGIVTGDSLFVDSLGRPDLLGDE 164

Query: 368 -QEGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRL-T 517
             +  ++ L+ ++      L DE ++YP H        D   +  T++  EKK+NP +  
Sbjct: 165 KTDELTQALFNTMREVFCKLRDEVIVYPCHAAGSACGPDIGNRLHTTIGYEKKHNPFMQM 224

Query: 518 KSLAEFVEIMDNLNLP----YPKM 577
           +++ EF + + +   P    YPKM
Sbjct: 225 ETIEEFKKAVQDSAPPVPTHYPKM 248


>UniRef50_Q22PH1 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 538

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 13/112 (11%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS----LAF 322
           G K + G  + A  DIH+  DG+ ++ G+ +L    TPGHT     ++  +        +
Sbjct: 153 GAKIIYGPGAQALYDIHVAKDGEEIQLGNIKLQVLHTPGHTTESSCFLLKDSKNQPHSVY 212

Query: 323 TGDTLLIRGCGRTDFQEGNSET--------LYKSVHNRIFTLPDEYVLYPAH 454
           TGDTL +   GR D    + +         L+ S+ N++  LPD  +++P+H
Sbjct: 213 TGDTLFLGEVGRPDLAVKSGQITEKDLAGMLFDSIKNKLLPLPDNVIVFPSH 264


>UniRef50_O54661 Cluster: Putative uncharacterized protein; n=1;
           Halobacterium salinarum|Rep: Putative uncharacterized
           protein - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 369

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 43/134 (32%), Positives = 64/134 (47%), Gaps = 13/134 (9%)
 Frame = +2

Query: 179 KDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGR 358
           KD+ A     L DG  V  G  ++    TPGH+ G +++   E +   TGDTL     GR
Sbjct: 194 KDALAVDATPLEDGQTVTVGRLDIEVIHTPGHSEGSVSFDV-EGAALLTGDTLFHDSVGR 252

Query: 359 TDF----------QEGNSETLYKSVHNRIFTLPDEYVLYPAHD---YRGQTATSVAEEKK 499
            +            EGN+ TLY+S+  R+   PD+ ++ PAHD        A ++AE ++
Sbjct: 253 VELGVEAGIEDADVEGNAATLYESL-QRLLDRPDDALVLPAHDPGSPEPPVAATLAEVRE 311

Query: 500 YNPRLTKSLAEFVE 541
            N  L +    FVE
Sbjct: 312 RNDDLGRDREAFVE 325


>UniRef50_Q8NQ06 Cluster: Zn-dependent hydrolases, including
           glyoxylases; n=4; Corynebacterium|Rep: Zn-dependent
           hydrolases, including glyoxylases - Corynebacterium
           glutamicum (Brevibacterium flavum)
          Length = 213

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/102 (30%), Positives = 49/102 (48%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L+DG+ +     E      PGH+ GC   +  E    F+GD L     GRTDF+  +++ 
Sbjct: 115 LVDGETITLAGEEFTLKHAPGHSPGCTLIVGKEY--CFSGDVLFKGSIGRTDFEWSDADA 172

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           + +S+   +  L D   + P H   G T T++  E+  NP L
Sbjct: 173 MNESLRTAVLPLDDALQILPGH---GPT-TTMRAERTGNPFL 210


>UniRef50_Q8D376 Cluster: YcbL protein; n=1; Wigglesworthia
           glossinidia endosymbiont of Glossina brevipalpis|Rep:
           YcbL protein - Wigglesworthia glossinidia brevipalpis
          Length = 214

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           DGD+++  SHE      PGH+ G + +    Q++  +GD L   G GR D   G+   + 
Sbjct: 116 DGDIIKLDSHEFKVIHCPGHSPGHVAFWNKNQNILLSGDILFNNGIGRIDLPGGDKNKII 175

Query: 395 KSVHNRIFTL-PDEYVLYPAH 454
            S+ N+I  L     +L P H
Sbjct: 176 GSIKNKILKLCKKNIMLLPGH 196


>UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase
           cytoplasmic; n=2; Candidatus Pelagibacter ubique|Rep:
           Hydroxyacylglutathione hydrolase cytoplasmic -
           Candidatus Pelagibacter ubique HTCC1002
          Length = 239

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 4/137 (2%)
 Frame = +2

Query: 167 SVIG----KDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334
           SVIG    KD   + DI + D D+    + +      PGHT G + +  + +   FTGDT
Sbjct: 73  SVIGYKGDKDRIPEIDILVGDQDIWHEENFQAKIFHIPGHTLGHICFYFYNEESVFTGDT 132

Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           L   GCG+    EG    +Y S+  +I  LP++  +Y  H+Y  Q +       + N  L
Sbjct: 133 LFSLGCGK--IFEGTYSQMYNSL-MKIKALPEKTKIYCGHEYTKQNSKFCIAHDQDNENL 189

Query: 515 TKSLAEFVEIMDNLNLP 565
              +    E ++  NLP
Sbjct: 190 KVKIKLIDEKLEK-NLP 205


>UniRef50_A0R0C8 Cluster: Metallo-beta-lactamase family protein;
           n=2; Corynebacterineae|Rep: Metallo-beta-lactamase
           family protein - Mycobacterium smegmatis (strain ATCC
           700084 / mc(2)155)
          Length = 210

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 33/97 (34%), Positives = 48/97 (49%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           DG +++ G  E+ A  TPGH+ G + +   E +   +GDTL   G G T     +  T+ 
Sbjct: 110 DGLVLKAGEIEVHALHTPGHSPGSVCWSIPELNAVISGDTLFQGGPGATGRSYSDFPTIL 169

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
            S+ NR+  LP E V+Y  H   G T T   E   Y+
Sbjct: 170 DSIKNRLGLLPAETVVYTGH---GDTTTIGGELVNYD 203


>UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3;
           Methanosarcina|Rep: Metallo-beta-lactamase -
           Methanosarcina acetivorans
          Length = 457

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 43/138 (31%), Positives = 62/138 (44%), Gaps = 20/138 (14%)
 Frame = +2

Query: 233 FGSHELLAAATPGHTNGCLTYIC------HEQSLAFTGDTLLIRGCGRTDFQEGN----- 379
           FG+ +L A  TPGHT+  ++Y+        E  + FTGD L +   GRTD          
Sbjct: 97  FGALKLTALHTPGHTDESMSYVLTDPDAGKEPIMVFTGDALFVGDVGRTDLYGPEEVPRL 156

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHD--------YRGQTATSVAEEKKYNPRLTKS-LAE 532
           +  LY S+ N+I  L D  +L PAH            +  +++  EK  NP L K+   E
Sbjct: 157 AANLYDSIFNKILPLGDGVILCPAHGAGSLCGGAISNREYSTLGLEKVQNPVLKKTEKEE 216

Query: 533 FVEIMDNLNLPYPKMINK 586
           FV+      L +P    K
Sbjct: 217 FVKFKLEEKLEFPPYFKK 234


>UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB;
           n=1; Bdellovibrio bacteriovorus|Rep:
           Hydroxyacylglutathione hydrolase GloB - Bdellovibrio
           bacteriovorus
          Length = 251

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           AD  L +GD V  G  +      PGHT G + Y   +    F+GD +   GCGR    EG
Sbjct: 91  ADQWLKEGDSVTCGPWDFTVMELPGHTLGHIAYWNQKHKWLFSGDVIFGLGCGR--LFEG 148

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDY 460
             E  Y+S+  RI  LP + ++Y  H+Y
Sbjct: 149 TFEQGYESL-QRIKKLPPQTLIYCTHEY 175


>UniRef50_A4IPS9 Cluster: Metallo-beta-lactamase family protein;
           n=2; Geobacillus|Rep: Metallo-beta-lactamase family
           protein - Geobacillus thermodenitrificans (strain
           NG80-2)
          Length = 378

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 36/113 (31%), Positives = 60/113 (53%), Gaps = 6/113 (5%)
 Frame = +2

Query: 134 GKLKSLVPGTKSVIGKDSGAQADIHLLDG-DLVRFGS-H-ELLAAATPGHTNGCLTYICH 304
           GK  +   G    + K  GA  D   L+  + + F + H E+LA  TPGHT G +++  +
Sbjct: 180 GKALAERTGAAYYLMKSEGAVFDFEPLEQHETIDFENVHLEVLAVKTPGHTPGSVSFFVN 239

Query: 305 EQSLAFTGDTLLIRGCGRTDF---QEGNSETLYKSVHNRIFTLPDEYVLYPAH 454
            + L F+GDT+ + G GR D        +E LY +V+ ++  + D+ ++ PAH
Sbjct: 240 GKWL-FSGDTIFVGGLGRPDLGGKVAEWAEDLYHTVYEKVAAMADDVIVLPAH 291


>UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrolase
           GloB; n=1; Idiomarina baltica OS145|Rep: Probable
           hydroxyacylglutathione hydrolase GloB - Idiomarina
           baltica OS145
          Length = 252

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 5/150 (3%)
 Frame = +2

Query: 131 LGKLKSLVPGTKSVIGKDSGA--QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICH 304
           L  LK+  P T    G D+ A    D  +++GD V+         ATPGHT   +++  +
Sbjct: 62  LEALKARFPATS--YGPDNPAIKGIDYAVMEGDTVQIAGLRFDVLATPGHTLDHISF--Y 117

Query: 305 EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSV 484
             +  F GDTL   GCGR    EG  E L+ S  +++  LP E  ++ AH+Y     T  
Sbjct: 118 GDTALFCGDTLFSGGCGR--MFEGTPE-LFVSSLDKLRRLPGETRVFCAHEYTQANLTFA 174

Query: 485 AEEKKYNPRLTKSLAEFVEIM---DNLNLP 565
           +  +  N  L KS  E +++M   D + LP
Sbjct: 175 SLVEPDNAVL-KSYLEKIKLMRQNDQITLP 203


>UniRef50_Q22YX3 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 524

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 12/113 (10%)
 Frame = +2

Query: 152 VPGTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS----L 316
           + G   V G  +  + +I +  D +++  GS +L    TPGHT     Y+  +++     
Sbjct: 81  ITGATIVFGPTASPKYEIKVASDEEILEIGSVKLQVLHTPGHTPESSCYLLLDENNTAQC 140

Query: 317 AFTGDTLLIRGCGRTDFQEGNSET-------LYKSVHNRIFTLPDEYVLYPAH 454
            FTGDTL +   GR D    ++ T       L+ S+ ++IF LP + ++YPAH
Sbjct: 141 VFTGDTLFLGDVGRPDLACNSNVTKEDLAGQLFDSLRSKIFKLPRDIIVYPAH 193


>UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24;
           Euteleostomi|Rep: Uncharacterized protein HAGHL - Homo
           sapiens (Human)
          Length = 291

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
 Frame = +2

Query: 137 KLKSLVPGTKSVIGKDSGA-QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYI----- 298
           +L  L PG  +V+G D         L  G+ +RFG+  +    TPGHT G ++Y      
Sbjct: 65  ELARLRPGL-AVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDD 123

Query: 299 CHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
           C +    F+GD L + GCG     EG+++ +Y+S+   + TLP E  ++  H++
Sbjct: 124 CPDPPALFSGDALSVAGCG--SCLEGSAQQMYQSL-AELGTLPPETKVFCGHEH 174


>UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Filobasidiella neoformans|Rep:
           Hydroxyacylglutathione hydrolase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 274

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
 Frame = +2

Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAA-TPGHTNGCLTYICHEQS 313
           K  SL P  K   G       +  + DGD    G    +    TP HT   + +   ++ 
Sbjct: 88  KFLSLHPNLKVYAGSTQSPGTNTVVKDGDTFTLGQDITVKCLHTPCHTQDSICFFLEDKK 147

Query: 314 LA----FTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
                 FTGDTL + GCGR  F EG  E ++ ++  ++  LP++ ++Y  H+Y
Sbjct: 148 TGQRGVFTGDTLFLAGCGR--FFEGTPEEMHAAL-TKLSNLPEDTIVYNGHEY 197


>UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase
           II, partial; n=1; Pan troglodytes|Rep: PREDICTED:
           similar to glyoxalase II, partial - Pan troglodytes
          Length = 284

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
 Frame = +2

Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLLDG-DLVRFGSHELLAAATPGHTNGCLTYICH--- 304
           KL  L  G K V G D    A  H +     ++ GS  +   ATP HT+G + Y      
Sbjct: 8   KLVELQSGLK-VYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPG 66

Query: 305 --EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
             E    FTGDTL + GCG+  F EG ++ + K++   +  LP +  +Y  H+Y
Sbjct: 67  GSEPPAVFTGDTLFVAGCGK--FYEGTADEMCKALLEVLGRLPPDTRVYCGHEY 118


>UniRef50_A0DS29 Cluster: Chromosome undetermined scaffold_61, whole
           genome shotgun sequence; n=5; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_61,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 483

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 46/176 (26%), Positives = 78/176 (44%), Gaps = 26/176 (14%)
 Frame = +2

Query: 152 VPGTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHT--NGCLTYICHEQS-LA 319
           + G + V+G  +  Q    +  D +L+  G   L    TPGHT  + C   +  ++  + 
Sbjct: 91  ITGAQIVLGPQAVTQYQAKIAQDEELLPLGRAYLRVVHTPGHTLESSCFVLVVDDKDHVV 150

Query: 320 FTGDTLLIRGCGRTDFQEGNS--------ETLYKSVHNRIFTLPDEYVLYPAHDYRGQ-- 469
           F+GD+L +   GR D    +S          LY S+ N+I  L D+ +LYP H       
Sbjct: 151 FSGDSLFLEEVGRPDLASKSSGLTTHQLASLLYHSLRNKIMKLEDDVILYPGHGAGSSCG 210

Query: 470 ------TATSVAEEKKYNPRLTK-SLAEFVEIMDNLNLP-----YPKMINKAGAGE 601
                 T +++ E+K  N  L   +  EFV+I  ++  P     +   +N+ GA +
Sbjct: 211 KAIGAGTVSTIGEQKLKNWALQNITEEEFVKISTDIPAPPQYFFHDVQLNRQGAND 266


>UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;
           Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Homo
           sapiens (Human)
          Length = 260

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
 Frame = +2

Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLLDG-DLVRFGSHELLAAATPGHTNGCLTYICH--- 304
           KL  L  G K V G D    A  H +     ++ GS  +   ATP HT+G + Y      
Sbjct: 65  KLVKLESGLK-VYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPG 123

Query: 305 --EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
             E    FTGDTL + GCG+  F EG ++ + K++   +  LP +  +Y  H+Y
Sbjct: 124 GSEPPAVFTGDTLFVAGCGK--FYEGTADEMCKALLEVLGRLPPDTRVYCGHEY 175


>UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to
           myofibrillogenesis regulator 1; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to myofibrillogenesis
           regulator 1 - Monodelphis domestica
          Length = 286

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 5/103 (4%)
 Frame = +2

Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQ-----SLAFTGDTLLIRGCGRTDFQEGNSE 385
           D+V  G  +  A ATPGHT G + Y+   +     S  F+GD L + GCG    +E  S 
Sbjct: 142 DMVSVGRLQFQALATPGHTRGHMVYVLDGEPYKGPSCLFSGDLLFLSGCGHEYSEENLSF 201

Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
                  N       ++V      YR    +++ EEK YNP L
Sbjct: 202 AGLVEPENMAREKKMQWVQQQRLQYRSTCPSTLGEEKTYNPFL 244


>UniRef50_Q4JWL1 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           uncharacterized protein - Corynebacterium jeikeium
           (strain K411)
          Length = 213

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 31/107 (28%), Positives = 52/107 (48%)
 Frame = +2

Query: 170 VIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRG 349
           ++ ++S   A    +D +  R+    +    TPGH+ GC+      Q    +GDTL   G
Sbjct: 98  MLWEESNGDAPFTPIDVEDPRWADWGVRLYHTPGHSPGCIVVEVPGQHALLSGDTLFNGG 157

Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAE 490
            G T  +  +  T+ +S+ +++F LP +  +YP H   G T T  AE
Sbjct: 158 PGATGRKYSSFPTIIESLQSKVFILPHDMKVYPGH---GDTTTVGAE 201


>UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Moritella sp. PE36|Rep: Hydroxyacylglutathione hydrolase
           - Moritella sp. PE36
          Length = 258

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 28/71 (39%), Positives = 42/71 (59%)
 Frame = +2

Query: 248 LLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLP 427
           L   ATPGH    + Y  + Q++ F+GDTL   GCGR    +G++  L+ S+  RI  L 
Sbjct: 107 LTVMATPGHKREHVVY--YNQTMLFSGDTLFSGGCGR--LLDGSAAELFSSL-QRIKALD 161

Query: 428 DEYVLYPAHDY 460
           +  ++YPAH+Y
Sbjct: 162 ENILVYPAHEY 172


>UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4;
           Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
           Pseudomonas stutzeri (strain A1501)
          Length = 292

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 2/130 (1%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYI--CHEQSLAFTGDTLLIRGCGRTDFQE 373
           D  L DG  +      L   A PGHT G + Y     +Q    +GDTL   GCGR    E
Sbjct: 121 DEALSDGQRIEVLGKRLQIIAVPGHTLGHIAYFHADPDQPWLLSGDTLFAAGCGR--LFE 178

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDN 553
           G  E +++S+  R+ + PD  ++Y  H+Y           + +N  +   + E  ++ + 
Sbjct: 179 GTPEQMFESL-TRLASAPDHTLVYCTHEYTLSNLRFAQAVEPHNADIAARIGEVTQLREA 237

Query: 554 LNLPYPKMIN 583
                P  ++
Sbjct: 238 GRFSLPSRLD 247


>UniRef50_A4E7W3 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 229

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHT-NGCLTYICHEQ-SLAFTGDTLLIRGCGRTDFQEGNS 382
           L +GD +  G   L    TPGHT  G + +   EQ ++AF GDTL     GRTD   G+ 
Sbjct: 128 LAEGDTIELGDICLQVIETPGHTPGGIVLFAATEQGNIAFVGDTLFPGSHGRTDLSGGDE 187

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
             +  S+     TLP + V    H      +T++A E   NP
Sbjct: 188 AAIMCSLSKLAKTLPPDTVCLTGHG----DSTTMARELMQNP 225


>UniRef50_UPI0000DAE586 Cluster: hypothetical protein
           Rgryl_01000658; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000658 - Rickettsiella
           grylli
          Length = 257

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 40/129 (31%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
 Frame = +2

Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKS 400
           +L  + S E+LA   PGHT G + Y  +   L F GDTL   GCGR    EG  + +  S
Sbjct: 98  ELTHWPSFEILAI--PGHTLGHIAY--YGNHLLFCGDTLFTAGCGR--LFEGTPDQMLNS 151

Query: 401 VHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLP-YPKM 577
           +  ++  LPDE  +Y  H+Y           +  N  + K L +  E+    NLP  P +
Sbjct: 152 L-EKLAQLPDETQIYCGHEYTLANLNFAQTIEPDNTHIKKRLEKTRELRQK-NLPCVPSL 209

Query: 578 INKAGAGEP 604
           + +     P
Sbjct: 210 LAEERLSNP 218


>UniRef50_Q8REE5 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Fusobacterium nucleatum|Rep: Hydroxyacylglutathione
           hydrolase - Fusobacterium nucleatum subsp. nucleatum
          Length = 207

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
 Frame = +2

Query: 167 SVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI 343
           ++ G+    + +IH + + D+V  G  +++   TPGHT G  ++   +  +  +GDTL  
Sbjct: 97  AIFGEFFKFKGEIHTVKESDMV--GDFKVID--TPGHTIGSKSFYYEKDKILISGDTLFR 152

Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
           R  GR D   G+ E L  S+  ++  LPDE V+Y  H       T++ EE+++  R+
Sbjct: 153 RSYGRYDLPTGSLEMLCHSL-KKLSKLPDETVVYNGH----TDNTTIGEERRFLERV 204


>UniRef50_Q89VZ3 Cluster: Bll0900 protein; n=9; Rhizobiales|Rep:
           Bll0900 protein - Bradyrhizobium japonicum
          Length = 230

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 30/103 (29%), Positives = 45/103 (43%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L +GD V  G  +      PGH+ G + +   E   A  GD L     GRTD   G+  T
Sbjct: 129 LEEGDTVSIGGLQFDILHCPGHSPGSVAFFNKELRFAHVGDVLFAGSVGRTDLPGGSHAT 188

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517
           L  S+  ++  L D+      H       +S+ +E+  NP +T
Sbjct: 189 LISSIKTKLLPLGDDVGFICGHG----AGSSIGQERMTNPFIT 227


>UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Bacillus|Rep: Hydroxyacylglutathione hydrolase -
           Bacillus amyloliquefaciens
          Length = 230

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 26/86 (30%), Positives = 42/86 (48%)
 Frame = +2

Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382
           I L DG     G   + +  TPGHT G + Y+  +    FTGDT+   GCG    +  ++
Sbjct: 105 IALEDGQTFAAGGFIIRSILTPGHTAGGMCYLLSDH--LFTGDTVFTEGCGICGDRGSSA 162

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDY 460
           E ++ S+     ++P    +YP H +
Sbjct: 163 EDMFHSIQRIKASIPPHVRVYPGHSF 188


>UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3;
           Leptospira|Rep: Zn-dependent hydrolase - Leptospira
           borgpetersenii serovar Hardjo-bovis (strain JB197)
          Length = 269

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 33/88 (37%), Positives = 47/88 (53%), Gaps = 4/88 (4%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAA-TPGHT--NGCLTYICHEQSLA-FTGDTLLIRGCGRTDFQEG 376
           L  GD +   S E L    TPGHT  + CL  + +++  A FTGDT+   G G      G
Sbjct: 93  LKKGDFLLRSSKEYLEILDTPGHTFCHVCLLLVENQKPKAIFTGDTIFNAGVGNCH-HGG 151

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDY 460
           + E L K++  + + L +E +LYP HDY
Sbjct: 152 DPEVLAKTILEQFYPLEEEILLYPGHDY 179


>UniRef50_Q9YCJ7 Cluster: Putative uncharacterized protein; n=1;
           Aeropyrum pernix|Rep: Putative uncharacterized protein -
           Aeropyrum pernix
          Length = 209

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 28/85 (32%), Positives = 40/85 (47%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D+ L+DG  +R     L A  TPGH+   +      + LAFTGD +     GR D   G+
Sbjct: 104 DVELVDGSTLRAAGLSLKAIHTPGHSPDHIVLYDQARGLAFTGDLIFRGSIGRVDIALGD 163

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAH 454
            E + +S+   +  LP    L P H
Sbjct: 164 GEAMARSLARIVRELPRGTRLLPGH 188


>UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4;
           Halobacteriaceae|Rep: Beta-lactamase domain protein -
           Halorubrum lacusprofundi ATCC 49239
          Length = 402

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 43/142 (30%), Positives = 62/142 (43%), Gaps = 7/142 (4%)
 Frame = +2

Query: 200 DIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           D+ L+ DGD    G   +    TPGHT G  +Y+  +  LA TGD L I    R D +EG
Sbjct: 224 DVTLVEDGDEFTVGDATVETVFTPGHTTGMTSYLLGDSLLA-TGDGLFIESVARPDLEEG 282

Query: 377 N------SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFV 538
           +      +  LY S+  R+ +L D  ++  AH        S A E   +   T  + E  
Sbjct: 283 DDGAPEAARMLYDSLQTRVLSLDDNVLVGGAH-------FSDAAEPAADGTYTAPIGELR 335

Query: 539 EIMDNLNLPYPKMINKAGAGEP 604
           E MD L+    + +    A  P
Sbjct: 336 ERMDALSADEDEFVETVLADMP 357


>UniRef50_Q2LSA2 Cluster: Zn-dependent hydrolases; n=1; Syntrophus
           aciditrophicus SB|Rep: Zn-dependent hydrolases -
           Syntrophus aciditrophicus (strain SB)
          Length = 215

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 32/87 (36%), Positives = 47/87 (54%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           + DI L +G+L   G+      +TPGH+ G L     E+ + F+GD    +G GR+D   
Sbjct: 107 EPDILLQEGEL-DIGTVRFQVISTPGHSPGSLCLYWPERKVLFSGDVAFDQGIGRSDLPG 165

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAH 454
           GN + L +S+  RI  L  EY+L P H
Sbjct: 166 GNGKLLKESL-RRIAQLDVEYLL-PGH 190


>UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep:
           Hydroxyacylglutathione hydrolase - Desulfuromonas
           acetoxidans DSM 684
          Length = 249

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 29/66 (43%), Positives = 34/66 (51%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGHT G   Y   +    F GDTL   GCGR    EG  E LY S+  +I  LP+   L
Sbjct: 105 TPGHTRGDCCYYLPQCEALFCGDTLFSGGCGRV--FEGTMEQLYHSL-QKITALPETTRL 161

Query: 443 YPAHDY 460
           Y  H+Y
Sbjct: 162 YCGHEY 167


>UniRef50_A4W8U6 Cluster: Beta-lactamase domain protein; n=11;
           Gammaproteobacteria|Rep: Beta-lactamase domain protein -
           Enterobacter sp. 638
          Length = 215

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 31/105 (29%), Positives = 50/105 (47%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L +G+ V  G+  L     PGHT G + +   +  L  +GD +   G GR+DF  G+
Sbjct: 108 DRWLNEGESVNVGNVTLQILHCPGHTPGHIVFFDDQSRLLISGDVIFKGGVGRSDFPRGD 167

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
              L +S+  ++  L D+      H   G  +T +  E+ +NP L
Sbjct: 168 HGQLIQSIKQKLLPLGDDVTFIAGH---GPMST-LGYERLHNPFL 208


>UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 268

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 36/100 (36%), Positives = 50/100 (50%), Gaps = 5/100 (5%)
 Frame = +2

Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHE----QSLAFTGDTLLIRGCGRTDFQ 370
           +H  D      G   +   ATP HT   + Y   +    QS  FTGDTL I GCGR  F 
Sbjct: 92  VHDADRISELLGGVSIECVATPCHTQDHICYHVTDTTTAQSGVFTGDTLFISGCGR--FF 149

Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDY-RGQTATSVA 487
           EG+ + +  S  +R+ +LPD  ++Y  H+Y +   A S A
Sbjct: 150 EGHPQQML-SAMDRLSSLPDHTLVYCGHEYTKSNVAFSAA 188


>UniRef50_Q4JCD2 Cluster: Conserved protein; n=1; Sulfolobus
           acidocaldarius|Rep: Conserved protein - Sulfolobus
           acidocaldarius
          Length = 198

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 38/105 (36%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
 Frame = +2

Query: 212 LDGDL----VRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           +DGDL    + FG   +    TPGHT G ++++  +    FTGDTL     GR D   G+
Sbjct: 96  VDGDLKEGVINFGKILVKVIETPGHTLGSVSFMIEDN--LFTGDTLFNENIGRYDL-GGD 152

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514
            E L KS+  R+  L D   +YP H +     T++  EK  NP L
Sbjct: 153 REYLKKSL-RRLMDLEDLLNVYPGHGF----ITTLGYEKLNNPFL 192


>UniRef50_Q488C8 Cluster: Aminotransferase, class V; n=5;
           Alteromonadales|Rep: Aminotransferase, class V -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 778

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 37/145 (25%), Positives = 65/145 (44%), Gaps = 11/145 (7%)
 Frame = +2

Query: 143 KSLVPGTKSVIGKDSGAQAD-IHLLDGDLVRFGSHELLAAATPGHTNGCLTYI-CH---- 304
           K L       +G  +GAQ   IH      +  G   L+  ATPGHT+  ++ + C     
Sbjct: 500 KFLAEQQTEYLGWPAGAQTTTIHGQTFQYLILGDKWLIKVATPGHTDDSMSLLLCDPVTD 559

Query: 305 -----EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQ 469
                +   AF GD +L+   GR++F   ++  +Y S+      + +  ++ P+HDY  +
Sbjct: 560 SAEKLQVHYAFCGDLILMDSIGRSNFSTSSAPAMYSSLKLMKSLIGNNSLICPSHDYHNE 619

Query: 470 TATSVAEEKKYNPRLTKSLAEFVEI 544
             T +  E K N  L + +   ++I
Sbjct: 620 FTTCLETEMKRNSLLRQVINSEIDI 644


>UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep: Beta-lactamase
           domain protein - Clostridium beijerinckii NCIMB 8052
          Length = 224

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 25/84 (29%), Positives = 41/84 (48%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           D D +  G  ++    TPGHT G + +    +   FTGDT+ IRGCG    + G+   ++
Sbjct: 102 DSDKISIGKLKMDCVLTPGHTAGGMCFKLENK--LFTGDTIFIRGCGICTCKGGDYNEMF 159

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRG 466
           +S+           ++YP H + G
Sbjct: 160 ESIKKIKEIAKKNVLIYPGHYFEG 183


>UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           unclassified Gammaproteobacteria (miscellaneous)|Rep:
           Hydroxyacylglutathione hydrolase - marine gamma
           proteobacterium HTCC2143
          Length = 258

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 30/88 (34%), Positives = 46/88 (52%), Gaps = 4/88 (4%)
 Frame = +2

Query: 209 LLDGDLVRFGSH-ELLAAATPGHTNGCLTYICHEQSL---AFTGDTLLIRGCGRTDFQEG 376
           L  G+L+   +  +L    TPGHT   L ++  EQ +    FTGDTL   G G    + G
Sbjct: 92  LTAGELIDLDTGVQLRVLDTPGHTYAHLCFLVLEQGIEVAVFTGDTLFNAGVGHC--RSG 149

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDY 460
           + ++LY+++  +   L D   +YP HDY
Sbjct: 150 DVDSLYQTIAEQFHCLDDNVRVYPGHDY 177


>UniRef50_Q4QBB0 Cluster: Metallo-beta-lactamase family protein-like
           protein; n=3; Leishmania|Rep: Metallo-beta-lactamase
           family protein-like protein - Leishmania major
          Length = 380

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 35/101 (34%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
 Frame = +2

Query: 233 FGSHELLAAA-TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHN 409
           FG H +L    TPGH+ G +      + L FTGD L   G GR D   G+ E L +S+  
Sbjct: 268 FGPHSVLHYVFTPGHSPGHMMLALPRERLLFTGDVLFYNGVGRVDLPWGSGERLAESLLT 327

Query: 410 RIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAE 532
            +   PD  VL P H       T++  E++ N R  ++L E
Sbjct: 328 -LEGYPDNTVLLPGHG----RLTTLGRERREN-RALRALYE 362


>UniRef50_A5V0A4 Cluster: Beta-lactamase domain protein; n=2;
           Roseiflexus|Rep: Beta-lactamase domain protein -
           Roseiflexus sp. RS-1
          Length = 489

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 19/129 (14%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYI------CHEQSLAFTGDTLLIRGCGRTDFQE- 373
           DGD +R G+  + A  TPGHT   + Y         E  +  TGD+L I    RTD    
Sbjct: 102 DGDEIRIGNIIIRAIHTPGHTPEHMAYAVIDTPRASEPWMVLTGDSLFINDVARTDLVNL 161

Query: 374 --GNSETLYKSVHNRIFTLPDEYVLYPAH---------DYRGQTATSVAEEKKYNPRL-T 517
                E +Y S+  R+  LPD   +YPAH            G+  +++  E+++N  L  
Sbjct: 162 PLAGPEVIYTSI-QRLLELPDYCEIYPAHYGGSACGGKQMSGKPVSTIGFERRFNWMLQA 220

Query: 518 KSLAEFVEI 544
           + + EF+ +
Sbjct: 221 RDVHEFISL 229


>UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 318

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 5/116 (4%)
 Frame = +2

Query: 254 AAATPGHTNGCLTYICH-----EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIF 418
           A +TPGHT G + Y+ H          F+GD L + GCGR    EG    + +S+   + 
Sbjct: 160 AFSTPGHTAGHVVYLLHGAVFNSVDSLFSGDLLFLGGCGR--IFEGAPGEMLESLQT-VS 216

Query: 419 TLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLPYPKMINK 586
           +L D+ +L+P HDY  +        +  N  L   +   VE+ +N  +  P  I +
Sbjct: 217 SLKDDTLLWPGHDYAMKNLMFALTIEPSNYHLRAKMDWVVEMRNNKYMTSPSTIGE 272


>UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Neptuniibacter caesariensis|Rep:
           Metallo-beta-lactamase superfamily protein -
           Neptuniibacter caesariensis
          Length = 257

 Score = 49.6 bits (113), Expect(2) = 3e-05
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYIC--HEQSLAFTGDTLLIRGCGRTDFQEGNS 382
           L DGD ++     +   A PGHT   ++Y    H+  L F GDTL + GCGR    EG +
Sbjct: 90  LNDGDSIQLMGASVAIKAIPGHTLDHISYYSERHKPQL-FCGDTLFLAGCGR--LFEGTA 146

Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDY 460
           + +  ++ N   +LPD+  +Y  H+Y
Sbjct: 147 KQMLNAM-NYFASLPDDTEVYCTHEY 171



 Score = 20.6 bits (41), Expect(2) = 3e-05
 Identities = 8/11 (72%), Positives = 9/11 (81%)
 Frame = +2

Query: 476 TSVAEEKKYNP 508
           TS+AEEK  NP
Sbjct: 209 TSIAEEKLINP 219


>UniRef50_Q3WFW5 Cluster: Beta-lactamase-like; n=1; Frankia sp.
           EAN1pec|Rep: Beta-lactamase-like - Frankia sp. EAN1pec
          Length = 346

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDF 367
           G +AD+ LLDG  V      L+A  TPGHT G L +   E+ L FTGD +L +       
Sbjct: 160 GIEADVELLDGAAVPGTGGALVAIHTPGHTTGHLCFHDRERGLVFTGDHVLPKVTPNVAL 219

Query: 368 QEGN-SETLYKSVHNRIF--TLPDEYVLYPAHDY 460
           + G+ ++ L   + +  +   LPD  +  P H++
Sbjct: 220 RPGSAADPLLAFLDSLRYLRDLPDNLLALPGHEW 253


>UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Marinomonas|Rep: Hydroxyacylglutathione hydrolase -
           Marinomonas sp. MWYL1
          Length = 257

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS-LAFTGDTLLIRGCGRTDFQEGNSETL 391
           DGD +   S      ATPGHT   L Y   +++ +  +GDTL   GCGR    EG  E +
Sbjct: 90  DGDRILVFSKVFTVIATPGHTLDHLCYFSEQETPILLSGDTLFKGGCGR--IMEGTHEQM 147

Query: 392 YKSVHNRIFTLPDEYVLYPAHDY 460
             ++  +I  LP++ ++Y  H+Y
Sbjct: 148 LAAM-IKISGLPNDTLIYGTHEY 169


>UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein;
           n=4; Alphaproteobacteria|Rep: Metallo-beta-lactamase
           family protein - Oceanicaulis alexandrii HTCC2633
          Length = 255

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 30/81 (37%), Positives = 40/81 (49%)
 Frame = +2

Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397
           GD V  G+         GHT G + Y   E  +AF GD+L   GCGR    EG  + +  
Sbjct: 96  GDAVALGNLTARVMDVGGHTLGHVAYWFEEAGVAFVGDSLFALGCGR--MFEGTPQQMQA 153

Query: 398 SVHNRIFTLPDEYVLYPAHDY 460
            +  R+  LP E V+Y AH+Y
Sbjct: 154 GL-ARLRGLPPETVIYCAHEY 173


>UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep:
           Orf c06001 protein - Sulfolobus solfataricus
          Length = 247

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 38/139 (27%), Positives = 67/139 (48%), Gaps = 19/139 (13%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS---------LAFTGDTLLIRGCGRTDF 367
           +G+ ++ G+ ++    TPGHT   ++ + +++             TGDTL + G GR D 
Sbjct: 96  NGEEIKAGNVKIKVLHTPGHTPDSISVLIYDRRRDESWNEPWAILTGDTLFVGGLGRIDI 155

Query: 368 -QEGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRL-T 517
             E   E LY S+  ++  LPD   +YPAH           G+ ++++  EK++N     
Sbjct: 156 GGENAEENLYYSL-AKLKELPDYVEIYPAHTAGSVCGIGISGKPSSTIGFEKRFNSLFRI 214

Query: 518 KSLAEFVEIMDNLNLPYPK 574
            +  EFV  +  + +P PK
Sbjct: 215 NNKDEFVNRIREVKMPKPK 233


>UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrolase
           with metallo- hydrolase/oxidoreductase domain; n=4;
           Proteobacteria|Rep: Putative hydroxyacylglutathione
           hydrolase with metallo- hydrolase/oxidoreductase domain
           - Pseudoalteromonas tunicata D2
          Length = 261

 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 26/67 (38%), Positives = 39/67 (58%)
 Frame = +2

Query: 260 ATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYV 439
           ATPGHT   + Y   +Q   F GDTL   GCGR    EG ++ +++S+  ++  LPD+  
Sbjct: 112 ATPGHTLDHICYYEPQQDWLFCGDTLFSGGCGR--LFEGTADQMFQSM-VKLSQLPDKTA 168

Query: 440 LYPAHDY 460
           +Y  H+Y
Sbjct: 169 VYCTHEY 175


>UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Reinekea sp. MED297|Rep: Hydroxyacylglutathione
           hydrolase - Reinekea sp. MED297
          Length = 258

 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLA-----FTGDTLLIRGCGR 358
           ++DI L DG  VR G   L    TPGHT G   ++  +  L+        DTL   G G 
Sbjct: 87  ESDIWLEDGQEVRLGKETLTHYLTPGHTPGHGVFLYQDPQLSERDFLVCADTLFNAGVGN 146

Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
           T  + GN   LY++V      L  +  L+P HDY
Sbjct: 147 T--RSGNVSELYQTVDRLKSLLRPQTRLFPGHDY 178


>UniRef50_A0NAW9 Cluster: ENSANGP00000031703; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000031703 - Anopheles gambiae
           str. PEST
          Length = 144

 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 24/82 (29%), Positives = 40/82 (48%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388
           L +GD ++ G        TPGH+ G +TY   +     +GD L     GRTD  + N + 
Sbjct: 63  LNEGDELKLGDDVFHIYFTPGHSPGSITYHNPDGKFIISGDVLFEGSIGRTDLFKANFDQ 122

Query: 389 LYKSVHNRIFTLPDEYVLYPAH 454
           L  S+  ++  LP++  ++  H
Sbjct: 123 LIDSIKTKLLILPEDTQVFSGH 144


>UniRef50_Q6MFA0 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 210

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373
           +A+I L DGDL+  G        TPGH+ G + +    QS   +GDTL     G   F  
Sbjct: 105 KANIFLNDGDLIPVGQLTFKVIHTPGHSPGSVCFYEISQSKLLSGDTLFKGSIGNISFPT 164

Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAH 454
              + ++ S+ +++  LP    +YP H
Sbjct: 165 SQPDLMWTSL-DKLAQLPPSTSVYPGH 190


>UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter
           sp. BAL39|Rep: Rhodanese-like protein - Pedobacter sp.
           BAL39
          Length = 459

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 13/93 (13%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS---LAFTGDTLLIRGCGRTDFQE--GN 379
           +G  +  G  +L +  TPGH+   +  I  +       FTGDTL I  CGR D +E  GN
Sbjct: 93  EGAEIVLGELKLKSIHTPGHSPDSICIILEQNGNDKAVFTGDTLFIGDCGRPDLRESVGN 152

Query: 380 --------SETLYKSVHNRIFTLPDEYVLYPAH 454
                   +  +Y S+  ++  L DE ++YPAH
Sbjct: 153 LTAKRDELAAQMYYSLREKLMALEDEVLVYPAH 185


>UniRef50_A4IWV0 Cluster: Metallo-beta-lactamase superfamily
           protein; n=11; Francisella tularensis|Rep:
           Metallo-beta-lactamase superfamily protein - Francisella
           tularensis subsp. tularensis (strain WY96-3418)
          Length = 252

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 26/87 (29%), Positives = 40/87 (45%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           DI++ DG  +  G         PGH +  + ++  ++   F GDTL   G G    +  +
Sbjct: 87  DIYVKDGSFINLGFTSFRVMYIPGHIDDHVCFLFEQERALFCGDTLFNAGVGGVQAESAD 146

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDY 460
              LY S+  +I  L  +   YPAHDY
Sbjct: 147 INQLYDSL-VKITKLDGDIKPYPAHDY 172


>UniRef50_A3Q4D8 Cluster: Beta-lactamase domain protein; n=8;
           Actinomycetales|Rep: Beta-lactamase domain protein -
           Mycobacterium sp. (strain JLS)
          Length = 453

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 17/126 (13%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS----LAFTGDTLLIRGCGRTDF----- 367
           +GD++  G   L    TPGHT+  ++Y+  + +      FTG ++L    GRTD      
Sbjct: 91  EGDVIDAGPIRLEVLHTPGHTHHHVSYVLSDDTGTVHGVFTGGSMLFGTTGRTDLVGPDD 150

Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAHDY--------RGQTATSVAEEKKYNPRLTKS 523
            E  +   Y SV      LP + V+YP H +            A+++ E+ + NP LTK 
Sbjct: 151 TEKLTHAQYHSVRKIADRLPADTVVYPTHGFGSFCSATPASGDASTIGEQWQANPALTKD 210

Query: 524 LAEFVE 541
              FV+
Sbjct: 211 EQSFVD 216


>UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=2; Prochlorococcus marinus|Rep: Putative
           hydroxyacylglutathione hydrolase - Prochlorococcus
           marinus (strain AS9601)
          Length = 303

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 1/130 (0%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICH-EQSLAFTGDTLLIRGCGRTDFQEG 376
           ++ + DG+ +     E+      GHT+  + +  + E  + F GDTL   GCGR    EG
Sbjct: 150 NVSVEDGETLNILGEEVKIIEVLGHTSSHIAFFLNGENPVLFIGDTLFSGGCGR--IFEG 207

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNL 556
             + +Y S+  RI +LP   ++Y AH+Y           K  +  +   L+E  + +   
Sbjct: 208 TYQQMYSSL-ERIKSLPKNTLIYCAHEYTKANILWALNLKPKDQDIKNKLSEVEKKLSLN 266

Query: 557 NLPYPKMINK 586
            L  P ++++
Sbjct: 267 ELTIPFLLDE 276


>UniRef50_A0LJP1 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 209

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 29/81 (35%), Positives = 43/81 (53%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L +G+L   G  +L    TPGH+ G ++    E+ + FTGD +   G GRTD   GN
Sbjct: 103 DFFLAEGELDVKGL-KLEIIHTPGHSPGSVSIYWRERKVLFTGDVIFKEGLGRTDLPGGN 161

Query: 380 SETLYKSVHNRIFTLPDEYVL 442
            E L +S+  R+     E++L
Sbjct: 162 GELLKRSI-KRLSEFDAEWML 181


>UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 617

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 37/102 (36%), Positives = 50/102 (49%), Gaps = 12/102 (11%)
 Frame = +2

Query: 185 SGAQADIH-LLDGDLVRFGSHELLAAATPGHT-NGCLTYICHE----QSLAFTGDTLLIR 346
           SGA+  I  L +G   + G+  + A  TPGHT +G    +  E      + FTGDTL + 
Sbjct: 77  SGAKYKIEPLKEGSTFKVGAAMVKAVETPGHTPDGMCGLVFSEGDDQPKMIFTGDTLFVG 136

Query: 347 GCGRTDFQEG--NSETL----YKSVHNRIFTLPDEYVLYPAH 454
             GR D  EG   + TL    Y + HN +  LPD   + PAH
Sbjct: 137 SVGRPDLLEGKMTAATLASMSYDTWHNVLSKLPDTVAVLPAH 178


>UniRef50_Q7VR07 Cluster: Zn-dependent hydrolase; n=7;
           Gammaproteobacteria|Rep: Zn-dependent hydrolase -
           Blochmannia floridanus
          Length = 211

 Score = 49.2 bits (112), Expect = 7e-05
 Identities = 25/85 (29%), Positives = 38/85 (44%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L DGD ++ G  +      PGH+ G +      Q     GD L  +  GR+D   G+
Sbjct: 110 DFWLKDGDQIQVGYEKFNVLHCPGHSPGHVVLWNKLQKFIIMGDVLFKKHIGRSDLPGGD 169

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAH 454
              L  S+  ++ +L D+ V  P H
Sbjct: 170 YTVLMHSIRTKLLSLSDDIVFLPGH 194


>UniRef50_Q1Q513 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Putative
           uncharacterized protein - Candidatus Kuenenia
           stuttgartiensis
          Length = 461

 Score = 49.2 bits (112), Expect = 7e-05
 Identities = 39/130 (30%), Positives = 60/130 (46%), Gaps = 21/130 (16%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLA-------FTGDTLLIRGCGRTDF 367
           L +GD +  G+  L    TPGHT   ++ +  + S +        TGD L +   GR D 
Sbjct: 91  LKEGDTIELGTAILEVLHTPGHTPHSISLLVKDTSRSEEEPWFMLTGDLLFVGDVGRPDL 150

Query: 368 Q-----EGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNP 508
                 E   + LY+S++ ++  LPD   +YPAH            +T+T++  E+  NP
Sbjct: 151 AGKELLEKQVKNLYESIYKKLGKLPDRLGVYPAHGQGSLCGKGISSKTSTTLGYERHANP 210

Query: 509 RL-TKSLAEF 535
            L   SL EF
Sbjct: 211 LLRLDSLDEF 220


>UniRef50_Q0RV10 Cluster: Possible hydroxyacylglutathione hydrolase;
           n=2; Actinomycetales|Rep: Possible
           hydroxyacylglutathione hydrolase - Rhodococcus sp.
           (strain RHA1)
          Length = 381

 Score = 49.2 bits (112), Expect = 7e-05
 Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
 Frame = +2

Query: 209 LLDGDLVRFGSHELLAAAT--PGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382
           L DGD +  GS  + A     PGHT G    +  E  L   GDT+ +RG GR D      
Sbjct: 209 LKDGDQLDLGSAVVRAMTMHLPGHTPGTTALLVSETVL-LVGDTVFVRGLGRPDLTGQAD 267

Query: 383 E---TLYKSVHNRIFTLPDEYVLYPAH 454
           E    L++SVH R+  L    ++ PAH
Sbjct: 268 ELARDLFRSVHERLRPLDPRTIIAPAH 294


>UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Marinobacter|Rep: Hydroxyacylglutathione hydrolase -
           Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 /
           VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
           11845))
          Length = 263

 Score = 49.2 bits (112), Expect = 7e-05
 Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
 Frame = +2

Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYIC----HEQSLAFTGDTLLIRGCG 355
           GA   +H   GD V +        A PGHT   + Y      +++ + F GDTL + GCG
Sbjct: 85  GATNTVHA--GDEVVWEGITFNVLAVPGHTLDHIAYYSDTQVNDKPVLFCGDTLFVCGCG 142

Query: 356 RTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEF 535
           R    EG  E ++ S+   +  LPD   +Y AH+Y   T  ++   + + P   K+LAEF
Sbjct: 143 R--LFEGTPEQMHTSLQT-LRDLPDNTAVYCAHEY---TLANLRFARHWLPE-DKALAEF 195


>UniRef50_A1RAH8 Cluster: Metallo-beta-lactamase superfamily
           protein; n=2; Micrococcineae|Rep: Metallo-beta-lactamase
           superfamily protein - Arthrobacter aurescens (strain
           TC1)
          Length = 216

 Score = 49.2 bits (112), Expect = 7e-05
 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
 Frame = +2

Query: 128 ALGKLKSLVPGTKSVIGKDSGA---QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYI 298
           AL +L ++   + S    D+ A     D+ L  GD+ +F   E+ A    GHT G + ++
Sbjct: 80  ALPELVAVTGASTSAGADDADALPVPVDVRLGHGDVEQFDGFEVTAVHLRGHTPGSIAFV 139

Query: 299 CHE---QSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIF-TLPDEYVLYPAH 454
             +    +  F+GD+L   G G T        +L   V  R+F   PDE +++P H
Sbjct: 140 YQDPDGPAHIFSGDSLFPGGVGNTQNDPSRFTSLLNDVSERLFDAYPDETLVHPGH 195


>UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Magnetococcus sp. MC-1|Rep: Hydroxyacylglutathione
           hydrolase - Magnetococcus sp. (strain MC-1)
          Length = 254

 Score = 47.6 bits (108), Expect(2) = 8e-05
 Identities = 32/87 (36%), Positives = 43/87 (49%)
 Frame = +2

Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379
           D  L  G     G H++    TPGHT+G L Y  H     F GDTL   GCGR    EG 
Sbjct: 91  DEALRGGQTFCLGPHQVDTYHTPGHTSGHLCY--HIADCLFAGDTLFSYGCGR--LFEGT 146

Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDY 460
            + +++S+   +  LP+   L  AH+Y
Sbjct: 147 PQQMWQSL-LILRALPETTRLCCAHEY 172



 Score = 21.0 bits (42), Expect(2) = 8e-05
 Identities = 8/11 (72%), Positives = 10/11 (90%)
 Frame = +2

Query: 482 VAEEKKYNPRL 514
           +AEEK+YNP L
Sbjct: 212 LAEEKQYNPFL 222


>UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7;
           Bacteria|Rep: Beta-lactamase-like precursor -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 251

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 17/137 (12%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICH------EQSLAFTGDTLLIRGCGRTDFQEG 376
           DG  +  G+  +    TPGHT   +  +        E     TGDTL +   GR D    
Sbjct: 95  DGQRLEAGNVVVDILHTPGHTPDSICLLVRDLRRGDEPWFVITGDTLFVGAAGRPDLAGR 154

Query: 377 NSET---LYKSVHNRIFTLPDEYVLYPAHD--------YRGQTATSVAEEKKYNPRLTKS 523
             E    L+ ++H ++ TLP +  ++P H           G+ ++++  E+++NP L+ S
Sbjct: 155 EREMAGQLHDTLHAKLLTLPADLEIFPGHQAGSACGVGLSGKPSSTIGFERRFNPMLSMS 214

Query: 524 LAEFVEIMDNLNLPYPK 574
              FV+ +     P P+
Sbjct: 215 REAFVKALTADIPPQPQ 231


>UniRef50_Q0LHZ1 Cluster: Beta-lactamase-like; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Beta-lactamase-like -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 369

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 18/144 (12%)
 Frame = +2

Query: 227 VRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ------EGNSET 388
           ++ G+  + A ATPGHT   ++Y+  + S  F+GDTL +   GR D +      +  +  
Sbjct: 212 IQLGAATIQALATPGHTWESMSYLL-DGSHLFSGDTLFLAAVGRPDLEAQAAEAQQRASA 270

Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRG------QTATSVAEEKKYNPRLTKSLAEFVEIMD 550
           LY+S+   I  L    ++ P H  +           S+AE +   PRL ++ AEFV  + 
Sbjct: 271 LYQSLQT-ILALDPASIILPGHTSKPVAFDGVPIMASLAEVQTATPRLAQTEAEFVAGLT 329

Query: 551 NLNLPYPK------MINKAGAGEP 604
            +    P        +N+AGA  P
Sbjct: 330 AVRPATPPNHQTIVQLNQAGAALP 353


>UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=2; Theileria|Rep: Hydroxyacylglutathione
           hydrolase, putative - Theileria annulata
          Length = 362

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
 Frame = +2

Query: 140 LKSLVPGTKSVIGKDSGAQADIHL--LDGDLVRFGSHELLAAATPGHTNGCLTYIC---- 301
           +K LVP  + V+G        + L       + FG+  +       HT G + Y      
Sbjct: 175 IKKLVPDVE-VVGSSYEETPGVTLPVKHEQTLTFGNLVIKCLKASCHTLGHIMYYVYHPS 233

Query: 302 --HEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
             H+Q L F+GDTL I GCGR  F EG++ ++ + V   + +LP+  +LY  H+Y
Sbjct: 234 NDHQQPLLFSGDTLFISGCGR--FFEGDARSMMEIVET-VKSLPENTLLYCGHEY 285


>UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=2; Buchnera aphidicola|Rep: Probable
           hydroxyacylglutathione hydrolase - Buchnera aphidicola
           subsp. Acyrthosiphon pisum (Acyrthosiphon pisumsymbiotic
           bacterium)
          Length = 251

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 28/66 (42%), Positives = 41/66 (62%)
 Frame = +2

Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442
           TPGHT+G ++Y  + Q   F GDTL   GCGR  F+  + E +Y+S+   I +LPD  +L
Sbjct: 107 TPGHTSGHVSY--YSQPYIFCGDTLFSAGCGRV-FKNKHLE-MYRSI-KIISSLPDSTLL 161

Query: 443 YPAHDY 460
             +H+Y
Sbjct: 162 CCSHEY 167


>UniRef50_Q5HUY3 Cluster: Metallo-beta-lactamase family protein;
           n=6; Epsilonproteobacteria|Rep: Metallo-beta-lactamase
           family protein - Campylobacter jejuni (strain RM1221)
          Length = 198

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/106 (27%), Positives = 55/106 (51%)
 Frame = +2

Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370
           ++A+  + D +++  G  +      PGHT GC       +++ F+GD L  R  GR DF 
Sbjct: 92  SKANYLIDDENIISIGGLDFKFHFLPGHTPGCTMIEIVGKNIMFSGDFLFYRSIGRWDFP 151

Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508
             ++  + +S+  ++ T  +++ L P H   GQ  T++ EE+ + P
Sbjct: 152 YSDANLMKQSL-EKVMTYKEDFKLLPGH---GQ-ETTLKEEQVHLP 192


>UniRef50_A1SJB6 Cluster: Beta-lactamase domain protein; n=13;
           Actinomycetales|Rep: Beta-lactamase domain protein -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 237

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 27/83 (32%), Positives = 42/83 (50%)
 Frame = +2

Query: 266 PGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLY 445
           PG T G          + F+GD L     GRTD   G+ +T+ +S+ +++  L D+ V+ 
Sbjct: 151 PGGTRGAEPSGSDVSEVMFSGDLLFAGSIGRTDLPGGDHQTMLQSLKSKVLPLADDVVVL 210

Query: 446 PAHDYRGQTATSVAEEKKYNPRL 514
           P H   G+  TS+  E+  NP L
Sbjct: 211 PGH---GE-QTSIGRERATNPYL 229


>UniRef50_Q0W7P0 Cluster: Putative uncharacterized protein; n=1;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           uncharacterized protein - Uncultured methanogenic
           archaeon RC-I
          Length = 208

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 37/107 (34%), Positives = 48/107 (44%), Gaps = 2/107 (1%)
 Frame = +2

Query: 140 LKSLVPGTKSVIGKDSGA-QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSL 316
           +KS       + G DS   + D+ L DGD +  G  +L    TPGHT G +         
Sbjct: 80  IKSSKINCARMFGSDSPELKVDMVLKDGDEIDLGDVKLRVIHTPGHTPGSICLYEPVSKA 139

Query: 317 AFTGDTLLIR-GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAH 454
            FTGDT+    G GRTD   GN E +  S+     T  +   LYP H
Sbjct: 140 MFTGDTVFEEGGFGRTDI-GGNPEHMLSSL--ATLTRFEVVTLYPGH 183


>UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=13; Bacteria|Rep: Probable hydroxyacylglutathione
           hydrolase - Synechocystis sp. (strain PCC 6803)
          Length = 257

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
 Frame = +2

Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS-----LAFTGDTLLIRGCGRTDF 367
           + L DGD + F   E      PGHT G + Y     S       F GDT+   GCGR   
Sbjct: 90  VFLRDGDRLSFADREATVYFVPGHTRGHIAYYFAPGSGETIGDLFCGDTIFAGGCGR--L 147

Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
            EG    + +S+  ++  LPD+  L+ AH+Y
Sbjct: 148 FEGTPAQMVQSI-GKLRQLPDQTRLWCAHEY 177


>UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=2; Candidatus Blochmannia|Rep: Probable
           hydroxyacylglutathione hydrolase - Blochmannia
           floridanus
          Length = 256

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 28/88 (31%), Positives = 48/88 (54%)
 Frame = +2

Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376
           A I + +GD ++  + E+     PGHT   + +  + +S  F+GDT+   GCG    Q G
Sbjct: 86  ATITVSEGDTLQILNQEIKVLNFPGHTPHHIGF--YYKSWLFSGDTIFSAGCG--TIQTG 141

Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDY 460
            ++ +YKS+  +I  LP   ++Y  H+Y
Sbjct: 142 YTQAMYKSL-LKIQCLPKNTLIYSGHEY 168


>UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Deltaproteobacteria|Rep: Hydroxyacylglutathione
           hydrolase - Syntrophus aciditrophicus (strain SB)
          Length = 235

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/92 (31%), Positives = 43/92 (46%)
 Frame = +2

Query: 260 ATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYV 439
           ATPGHT   + +  H  ++  TGDTL     G      G+  + Y S+  +I TLP E V
Sbjct: 98  ATPGHTRDSICF--HTDTILLTGDTLFNGTVGNCF--SGDIHSFYSSIR-KILTLPPETV 152

Query: 440 LYPAHDYRGQTATSVAEEKKYNPRLTKSLAEF 535
           +Y  HDY   +       +  NP +   L+ +
Sbjct: 153 IYAGHDYVRDSLAMARHLEPDNPAIDDFLSVY 184


>UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Beta-lactamase-like -
           Clostridium cellulolyticum H10
          Length = 235

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 26/97 (26%), Positives = 49/97 (50%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           DG++++ G  ++    TPGHT G + +   + SL FTGDT+ + GCG      G++  ++
Sbjct: 114 DGEVIKLGYTDIKCILTPGHTMGGMCFFV-DGSL-FTGDTIFMEGCGICSNLGGDAGDMF 171

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505
            S++     +  +  +Y  H    Q   ++ +  K N
Sbjct: 172 HSINRIKAEVSHDTKMYSGHTIDRQPGCTLGDLIKNN 208


>UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_7,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 489

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHE----QSLAFTGDTLLIRGCGRTDFQEGNS 382
           D + ++ G  ++ A  TPGHT     ++ ++    Q   +TGDTL +   GR D    + 
Sbjct: 136 DNEFLKVGKVKIQALHTPGHTQESTCFLLYDEEGKQHSIYTGDTLFLGEVGRPDLAVKSD 195

Query: 383 ET-------LYKSVHNRIFTLPDEYVLYPAH 454
            T       LY S+  +I  LPD+ +++P H
Sbjct: 196 VTQYDLASLLYASLKQKILGLPDDVIVFPGH 226


>UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 659

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 35/123 (28%), Positives = 58/123 (47%), Gaps = 18/123 (14%)
 Frame = +2

Query: 218 GDLVRFGSH-ELLAAATPGHTNGCLTYICH--EQSLAFTGDTLLI--------------R 346
           G++ + G    + A  TP HT   + Y     EQ   FTGDTL I               
Sbjct: 477 GEVFKIGDRISVTALHTPCHTQDSICYFMQDGEQKAVFTGDTLFIGGMTEWINAESSAAA 536

Query: 347 GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY-RGQTATSVAEEKKYNPRLTKS 523
           GCGR  F EG +  ++K+++  + +LP++  +YP H+Y +G     +A  +    +  ++
Sbjct: 537 GCGR--FFEGTAPEMHKALNETLASLPEDTKVYPGHEYTKGNVKFCLAVSQSEPVKKLQA 594

Query: 524 LAE 532
            AE
Sbjct: 595 FAE 597


>UniRef50_Q2H306 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 256

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 13/103 (12%)
 Frame = +2

Query: 320 FTGDTLLIR--GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY-------RGQT 472
           F GD++     G  R DF  GN+  LY++   ++FTLP  Y +Y  HDY         Q 
Sbjct: 126 FCGDSIFNSDVGSARCDFPGGNANDLYQTA-TKLFTLPPAYKIYTGHDYPPKTPRATPQA 184

Query: 473 ATSVAEEKKYNPRLT--KSLAEFV--EIMDNLNLPYPKMINKA 589
           A++VAE+  +N  L    S A+FV      +  L  P++I++A
Sbjct: 185 ASTVAEQMAHNKHLKAGTSQADFVSWRTERDAGLAEPRLIHQA 227


>UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Saccharomycetaceae|Rep: Hydroxyacylglutathione hydrolase
           - Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 282

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
 Frame = +2

Query: 254 AAATPGHTNGCLTYICHE----QSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFT 421
           A  TP HT   + Y   +    +   FTGDTL I GCGR  F EG    +  +++  +  
Sbjct: 136 ALHTPCHTQDSICYYVKDAKTGEKAVFTGDTLFISGCGR--FFEGTGAEMNVALNKILAK 193

Query: 422 LPDEYVLYPAHDY 460
           LP +  +YP H+Y
Sbjct: 194 LPKDTKVYPGHEY 206


>UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathione
           hydrolase-like isoform 2; n=1; Pan troglodytes|Rep:
           PREDICTED: hydroxyacylglutathione hydrolase-like isoform
           2 - Pan troglodytes
          Length = 285

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
 Frame = +2

Query: 230 RFGSHELLAAATPGHTNGCLTYI-----CHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           +FG+  +    TPGHT G ++Y      C +    F+GD L + GCG     EG+++ +Y
Sbjct: 91  QFGAIHVRCLLTPGHTGGHMSYFLWEDDCPDPPALFSGDALSVAGCG--SCLEGSAQQMY 148

Query: 395 KSVHNRIFTLPDEYVLYPAHDY 460
           +S+   + TLP E  ++  H++
Sbjct: 149 QSL-AEMGTLPPETKVFCGHEH 169


>UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=1; Plesiocystis pacifica SIR-1|Rep: Probable
           hydroxyacylglutathione hydrolase - Plesiocystis pacifica
           SIR-1
          Length = 270

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 38/130 (29%), Positives = 56/130 (43%)
 Frame = +2

Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394
           +GD+VR G+ E     T GH +G ++Y   E  L F GDTL   GCG     +G + T++
Sbjct: 95  EGDVVRLGALEGQVMLTEGHIDGHVSYRFGE--LLFCGDTLFAGGCGY--LFDGPAATMH 150

Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLPYPK 574
            S+  R+  LP+   +  AH+Y           +  N  L + + E   I        P 
Sbjct: 151 ASL-QRLAGLPESTKVVCAHEYTQDNLRFAWSVEPDNAALAERIREVWAIRARGESTVPS 209

Query: 575 MINKAGAGEP 604
            I    A  P
Sbjct: 210 TIGLERATNP 219


>UniRef50_A4AQV7 Cluster: Metallo-beta-lactamase superfamily
           protein; n=17; Bacteroidetes|Rep: Metallo-beta-lactamase
           superfamily protein - Flavobacteriales bacterium
           HTCC2170
          Length = 492

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 25/161 (15%)
 Frame = +2

Query: 158 GTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYIC----HEQSLAF 322
           G + V G  +    D  +  D  +   G +++    TPGHT    TY+      +Q    
Sbjct: 92  GAQIVFGPTANPNYDALIAEDNQIFELGDYKIKVLHTPGHTMESTTYLLIDENDKQHGII 151

Query: 323 TGDTLLIRGCGRTDF---------QEGNSETLYKSVHNRIFTLPDEYVLYPAHD------ 457
           TGDTL I   GR D          +E  +  L+ S+ N+I  L D+ ++YP H       
Sbjct: 152 TGDTLFIGDVGRPDLAQHVVSELTEEKLAGHLFDSLRNKIMPLDDKLIVYPNHGAGSACG 211

Query: 458 --YRGQTATSVAEEKKYNPRLTKSLA--EFV-EIMDNLNLP 565
                +T  ++  +KK N  L   +   EF+ E++  L  P
Sbjct: 212 KMMSKETTDTLGHQKKVNYALRADMTKDEFIKELLTGLTAP 252


>UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=4; Proteobacteria|Rep:
           Hydroxyacylglutathione hydrolase precursor -
           Verminephrobacter eiseniae (strain EF01-2)
          Length = 258

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
 Frame = +2

Query: 179 KDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS---LAFTGDTLLIRG 349
           ++S  +  + L  GD V      L     PGHT G + Y C +     L F GDTL   G
Sbjct: 77  RESVPEPLVRLAQGDTVDVLGLRLEVIDVPGHTAGHIAYYCPQMDGAPLLFCGDTLFSGG 136

Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460
           CGR    EG    +  S+ +R+  LP   ++  AH+Y
Sbjct: 137 CGR--LFEGTPAQMLASL-DRLAALPGNTLVCCAHEY 170


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 636,683,416
Number of Sequences: 1657284
Number of extensions: 13417060
Number of successful extensions: 43010
Number of sequences better than 10.0: 460
Number of HSP's better than 10.0 without gapping: 40997
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42773
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 42732687689
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -