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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmov10c01
         (717 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to tRNA-dihyd...   254   2e-66
UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep: CG14...   235   1e-60
UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=...   217   2e-55
UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9; Magnoliop...   206   4e-52
UniRef50_UPI0000E472BC Cluster: PREDICTED: similar to tRNA-dihyd...   183   4e-45
UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1; ...   180   4e-44
UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2; ...   173   3e-42
UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Re...   169   4e-41
UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1;...   156   4e-37
UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of str...   155   1e-36
UniRef50_A7EHJ6 Cluster: Putative uncharacterized protein; n=2; ...   152   1e-35
UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3; ...   151   1e-35
UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of s...   150   4e-35
UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase;...   150   4e-35
UniRef50_P53720 Cluster: tRNA-dihydrouridine synthase 2; n=7; Sa...   147   3e-34
UniRef50_A5DYF6 Cluster: Putative uncharacterized protein; n=1; ...   143   4e-33
UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12...   140   4e-32
UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1; ...   133   5e-30
UniRef50_Q1DPY5 Cluster: Putative uncharacterized protein; n=1; ...   132   8e-30
UniRef50_A6R3V4 Cluster: Putative uncharacterized protein; n=1; ...   126   4e-28
UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1; ...   105   1e-21
UniRef50_Q38BB4 Cluster: TRNA-dihydrouridine synthase 2, putativ...    99   5e-20
UniRef50_Q24833 Cluster: Putative nitrogen fixation regulatory p...    97   5e-19
UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1; ...    91   3e-17
UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, wh...    86   7e-16
UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein; ...    83   9e-15
UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=...    83   9e-15
UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep: ...    82   2e-14
UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1; ...    81   4e-14
UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1; ...    80   5e-14
UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep: N...    80   5e-14
UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase;...    80   6e-14
UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1; ...    79   8e-14
UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11; S...    79   8e-14
UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1;...    77   3e-13
UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1;...    76   8e-13
UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel prot...    73   7e-12
UniRef50_A3AVU4 Cluster: Putative uncharacterized protein; n=1; ...    73   7e-12
UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative;...    73   7e-12
UniRef50_Q4Q231 Cluster: Dihydrouridine synthase domain protein-...    72   2e-11
UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein ECU07_...    71   3e-11
UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1; ...    70   5e-11
UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2; Cy...    70   7e-11
UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep:...    69   2e-10
UniRef50_Q2H6D9 Cluster: Putative uncharacterized protein; n=1; ...    68   2e-10
UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17; P...    68   3e-10
UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep: Lm...    67   4e-10
UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative...    67   5e-10
UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1;...    67   5e-10
UniRef50_Q7RX85 Cluster: Putative uncharacterized protein NCU000...    67   5e-10
UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1...    66   8e-10
UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5; Firm...    66   1e-09
UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1; Desu...    65   1e-09
UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829 p...    64   4e-09
UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3; Bacter...    63   6e-09
UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4; Prot...    63   6e-09
UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella ve...    63   8e-09
UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1;...    62   1e-08
UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=...    62   1e-08
UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10;...    61   2e-08
UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine...    61   2e-08
UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly d...    61   2e-08
UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protei...    61   2e-08
UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6; S...    61   2e-08
UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase; ...    61   2e-08
UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein;...    61   3e-08
UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative;...    61   3e-08
UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative;...    61   3e-08
UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10; S...    61   3e-08
UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2; Culi...    60   4e-08
UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 fami...    60   4e-08
UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=...    60   4e-08
UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3; Mo...    60   5e-08
UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel prot...    60   7e-08
UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putativ...    60   7e-08
UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15...    59   9e-08
UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2; ...    59   1e-07
UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1; Paraba...    58   2e-07
UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2; ...    58   2e-07
UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein Y37E11...    58   2e-07
UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2; ...    58   2e-07
UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1; ...    58   3e-07
UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779...    57   4e-07
UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative;...    57   4e-07
UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein,...    57   4e-07
UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 fami...    56   7e-07
UniRef50_A4S3Q5 Cluster: Predicted protein; n=2; Eukaryota|Rep: ...    56   7e-07
UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1; ...    56   7e-07
UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protei...    56   9e-07
UniRef50_A6VYA3 Cluster: TIM-barrel protein, yjbN family; n=8; P...    56   9e-07
UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase; ...    56   9e-07
UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 fami...    56   1e-06
UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1; Petr...    56   1e-06
UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231; ...    56   1e-06
UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Nov...    55   2e-06
UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1; ...    55   2e-06
UniRef50_UPI0000DAE45A Cluster: hypothetical protein Rgryl_01000...    55   2e-06
UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=2...    55   2e-06
UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR - Lepto...    55   2e-06
UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly d...    55   2e-06
UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus lu...    55   2e-06
UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultu...    54   3e-06
UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter ...    54   4e-06
UniRef50_Q010A0 Cluster: tRNA-dihydrouridine synthase; n=1; Ostr...    54   4e-06
UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6; Ga...    54   4e-06
UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel prot...    54   5e-06
UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putativ...    54   5e-06
UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel prot...    53   6e-06
UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 fami...    53   6e-06
UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=...    53   6e-06
UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA...    53   8e-06
UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24...    53   8e-06
UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI; ...    53   8e-06
UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1; ...    53   8e-06
UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4; Lept...    52   1e-05
UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=...    52   1e-05
UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781 p...    52   1e-05
UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3 fam...    52   1e-05
UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel prot...    52   1e-05
UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 fami...    52   1e-05
UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lambl...    52   1e-05
UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n...    52   2e-05
UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3; ...    52   2e-05
UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1; T...    52   2e-05
UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1; ...    52   2e-05
UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep...    51   2e-05
UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6; Sa...    51   2e-05
UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1...    51   2e-05
UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7; Chlamydi...    50   4e-05
UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2; ...    50   4e-05
UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4; Legio...    50   6e-05
UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2; Proteob...    50   6e-05
UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2;...    50   6e-05
UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein;...    50   6e-05
UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase; ...    50   6e-05
UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to dihydrouri...    50   8e-05
UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1; Thiomicro...    50   8e-05
UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel prot...    50   8e-05
UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1; ...    50   8e-05
UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214; ...    50   8e-05
UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Ther...    49   1e-04
UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep: CG1049...    49   1e-04
UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domai...    49   1e-04
UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1;...    49   1e-04
UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, wh...    49   1e-04
UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4; B...    48   2e-04
UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus lu...    48   2e-04
UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine syn...    48   2e-04
UniRef50_UPI0000499494 Cluster: conserved hypothetical protein; ...    48   2e-04
UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4; Therm...    48   2e-04
UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1; Vict...    48   3e-04
UniRef50_A4YUQ6 Cluster: Putative tRNA-dihydrouridine synthase; ...    48   3e-04
UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN f...    47   4e-04
UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein;...    47   4e-04
UniRef50_Q5KC68 Cluster: TRNA dihydrouridine synthase, putative;...    47   4e-04
UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22; Alph...    47   5e-04
UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1; Poly...    47   5e-04
UniRef50_A3VNG3 Cluster: Dihydrouridine synthase TIM-barrel prot...    47   5e-04
UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3; ...    47   5e-04
UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel prot...    46   7e-04
UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1; Sacc...    46   7e-04
UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1; ...    46   7e-04
UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21; C...    46   7e-04
UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1; Dicheloba...    46   7e-04
UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1; C...    46   7e-04
UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel prot...    46   0.001
UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel prot...    46   0.001
UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30; ...    46   0.001
UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: Ni...    46   0.001
UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10; ...    46   0.001
UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034,...    45   0.002
UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lambli...    45   0.002
UniRef50_UPI000023CFE7 Cluster: hypothetical protein FG01258.1; ...    45   0.002
UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2; ...    45   0.002
UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1; Marin...    45   0.002
UniRef50_Q4Q669 Cluster: Dihydrouridine synthase (Dus), putative...    45   0.002
UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8; Pr...    45   0.002
UniRef50_A5WG83 Cluster: TIM-barrel protein, yjbN family; n=4; M...    44   0.003
UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4; Bifid...    44   0.004
UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase; ...    44   0.004
UniRef50_Q9A7I4 Cluster: Nitrogen regulation protein Nifr3; n=2;...    44   0.005
UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3; ...    44   0.005
UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1; ...    44   0.005
UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 fami...    43   0.007
UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Re...    43   0.007
UniRef50_Q7R684 Cluster: GLP_574_116690_118078; n=1; Giardia lam...    43   0.007
UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2; Sinor...    43   0.009
UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4; Ne...    43   0.009
UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5; ...    42   0.011
UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putativ...    42   0.011
UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein;...    42   0.015
UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein;...    42   0.020
UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase; ...    42   0.020
UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5; Bacteri...    41   0.027
UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2; ...    41   0.027
UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1;...    41   0.027
UniRef50_Q6A959 Cluster: TIM-barrel enzyme, NifR3 family; n=1; P...    41   0.035
UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1; Chro...    41   0.035
UniRef50_A5KKR3 Cluster: Putative uncharacterized protein; n=1; ...    40   0.046
UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2; ...    40   0.046
UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase; ...    40   0.061
UniRef50_Q056Y8 Cluster: TRNA-dihydrouridine synthase A; n=1; Bu...    40   0.061
UniRef50_Q17M24 Cluster: tRNA-dihydrouridine synthase; n=1; Aede...    40   0.061
UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2; ...    40   0.081
UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225...    40   0.081
UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1; ...    40   0.081
UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5; Al...    39   0.11 
UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3;...    39   0.14 
UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7; B...    39   0.14 
UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase; ...    39   0.14 
UniRef50_Q7R3K2 Cluster: GLP_158_4738_3071; n=1; Giardia lamblia...    38   0.19 
UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1; ...    38   0.19 
UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26; P...    38   0.33 
UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3; Prot...    37   0.43 
UniRef50_Q47741 Cluster: Dihydroorotate dehydrogenase B, catalyt...    37   0.43 
UniRef50_O53835 Cluster: Probable tRNA-dihydrouridine synthase; ...    37   0.43 
UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1; ...    37   0.57 
UniRef50_Q1F0W8 Cluster: Dihydroorotate dehydrogenase 1; n=1; Cl...    37   0.57 
UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1; ...    37   0.57 
UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2; Gammapr...    37   0.57 
UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2; un...    37   0.57 
UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1; ...    37   0.57 
UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whol...    36   0.76 
UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2; Beta...    36   0.76 
UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase; ...    36   0.76 
UniRef50_O51679 Cluster: Histidine phosphokinase/phophatase, put...    36   1.00 
UniRef50_A5EXU5 Cluster: TRNA-dihydrouridine synthase A; n=1; Di...    36   1.00 
UniRef50_Q9RDC6 Cluster: Putative uncharacterized protein SCO249...    36   1.3  
UniRef50_Q97DM0 Cluster: Predicted TIM-barrel enzyme, nifR3 fami...    36   1.3  
UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2; Meth...    36   1.3  
UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4; Desu...    36   1.3  
UniRef50_Q8G660 Cluster: Dihydroorotate dehydrogenase; n=4; Bifi...    35   1.7  
UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1; Ca...    35   1.7  
UniRef50_Q7SGX4 Cluster: Putative uncharacterized protein NCU031...    35   1.7  
UniRef50_A6RVN2 Cluster: Putative uncharacterized protein; n=2; ...    35   1.7  
UniRef50_A4RL93 Cluster: Putative uncharacterized protein; n=1; ...    35   1.7  
UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1; Desu...    35   2.3  
UniRef50_A7AAN4 Cluster: Putative uncharacterized protein; n=2; ...    35   2.3  
UniRef50_A1RZC9 Cluster: Dihydroorotate dehydrogenase family pro...    35   2.3  
UniRef50_Q979G6 Cluster: Dihydroorotate dehydrogenase; n=4; Ther...    35   2.3  
UniRef50_UPI0000F1F64B Cluster: PREDICTED: hypothetical protein;...    34   3.0  
UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2; Prot...    34   3.0  
UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep: CG1046...    34   3.0  
UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2; Endopterygota|...    34   3.0  
UniRef50_Q23WS6 Cluster: Putative uncharacterized protein; n=1; ...    34   3.0  
UniRef50_O75864 Cluster: R32611_1; n=20; Euteleostomi|Rep: R3261...    34   3.0  
UniRef50_Q6D9Y3 Cluster: Enterobactin synthetase component F; n=...    34   4.0  
UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1; ...    34   4.0  
UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3; Alte...    34   4.0  
UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Re...    34   4.0  
UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3; ...    33   5.3  
UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2...    33   5.3  
UniRef50_Q39PB0 Cluster: Dihydroorotate dehydrogenase 1; n=81; B...    33   7.0  
UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel prot...    33   7.0  
UniRef50_A7BE39 Cluster: Putative uncharacterized protein; n=1; ...    33   7.0  
UniRef50_A0LD69 Cluster: Dihydroorotate dehydrogenase family pro...    33   7.0  
UniRef50_Q73RG6 Cluster: Dihydrouridine synthase, putative; n=1;...    33   9.3  
UniRef50_A3J321 Cluster: Putative uncharacterized protein; n=1; ...    33   9.3  
UniRef50_Q8IJJ6 Cluster: Putative uncharacterized protein; n=1; ...    33   9.3  
UniRef50_Q2NEH7 Cluster: Putative uncharacterized protein; n=1; ...    33   9.3  
UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8; Pr...    33   9.3  

>UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to
           tRNA-dihydrouridine synthase; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           tRNA-dihydrouridine synthase - Nasonia vitripennis
          Length = 505

 Score =  254 bits (622), Expect = 2e-66
 Identities = 121/167 (72%), Positives = 141/167 (84%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           + Y +K+I+APMVRIGTLPMRLLAL+YGADIVYTEELIDWK LRS RR N++L TVDY+D
Sbjct: 53  LTYADKLIMAPMVRIGTLPMRLLALEYGADIVYTEELIDWKLLRSVRRVNEVLGTVDYID 112

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGM 441
           +TDGTIVFRT   E+ +VVLQLGTCD  RALKVAKLVE DVA ID+NMGCPK FSI GGM
Sbjct: 113 RTDGTIVFRTSPIERDRVVLQLGTCDANRALKVAKLVEQDVAGIDVNMGCPKRFSILGGM 172

Query: 442 GVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
           G ALL +P+KA +IL+TLV  LSIPVTCKIR+L   E TL+LV+ L+
Sbjct: 173 GAALLKQPEKASEILRTLVGGLSIPVTCKIRVLGNVEDTLKLVDTLV 219


>UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep:
           CG1434-PA - Drosophila melanogaster (Fruit fly)
          Length = 473

 Score =  235 bits (574), Expect = 1e-60
 Identities = 113/183 (61%), Positives = 139/183 (75%)
 Frame = +1

Query: 31  RFKTFIT*SILLQFPINMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFL 210
           R  T +  S  ++    ++Y NK+ILAPMVR+GTLPMRLLAL+ GADIVYTEEL+D K +
Sbjct: 3   RLPTILRKSFSMKTRQRLDYRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLI 62

Query: 211 RSKRRFNDILNTVDYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA 390
           +S RR N  L TVD+VD +DGTIVFRTC +E  ++VLQ+GT D  RAL V KL++ D++ 
Sbjct: 63  KSIRRPNPALGTVDFVDPSDGTIVFRTCAQETSRLVLQMGTSDAGRALAVGKLLQRDISG 122

Query: 391 IDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELV 570
           +DINMGCPKEFSIKGGMG ALL+ PDKA  IL+TL   L IPVTCKIRIL   E T++LV
Sbjct: 123 LDINMGCPKEFSIKGGMGAALLADPDKAAHILRTLCSGLDIPVTCKIRILPDVEGTIDLV 182

Query: 571 NKL 579
            KL
Sbjct: 183 QKL 185


>UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=27;
           Eumetazoa|Rep: tRNA-dihydrouridine synthase 2-like -
           Homo sapiens (Human)
          Length = 493

 Score =  217 bits (531), Expect = 2e-55
 Identities = 106/168 (63%), Positives = 130/168 (77%)
 Frame = +1

Query: 76  INMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDY 255
           +++ Y NK+ILAPMVR+GTLPMRLLAL YGADIVY EELID K ++ KR  N++L+TVD+
Sbjct: 6   LSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDF 65

Query: 256 VDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKG 435
           V   D  +VFRTCE E+ +VV Q+GT D  RAL VA+LVE+DVA ID+NMGCPK++S KG
Sbjct: 66  V-APDDRVVFRTCEREQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKQYSTKG 124

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
           GMG ALLS PDK  +IL TLV     PVTCKIRIL + E TL LV ++
Sbjct: 125 GMGAALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLEDTLSLVKRI 172


>UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9;
           Magnoliophyta|Rep: OSIGBa0125M19.5 protein - Oryza
           sativa (Rice)
          Length = 319

 Score =  206 bits (503), Expect = 4e-52
 Identities = 97/166 (58%), Positives = 125/166 (75%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           M Y +K++LAPMVR+GTLP RLLA +YGADI Y EE+ID KFL+ +R  N+ L T D+++
Sbjct: 1   MEYRDKLVLAPMVRVGTLPFRLLAAEYGADITYGEEIIDHKFLKCERVTNESLGTTDFLE 60

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGM 441
           +   T+VFRTC +E+ +VV Q+GT D  RALK A+LV +DVAAIDINMGCPK FS+ GGM
Sbjct: 61  RGTDTVVFRTCPQERDRVVFQMGTSDAVRALKAAQLVCNDVAAIDINMGCPKSFSLSGGM 120

Query: 442 GVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
           G ALLSKP+  + IL TL  NL   VTCKIR+L T + T+EL  ++
Sbjct: 121 GAALLSKPELIHDILTTLRRNLDTTVTCKIRLLNTRQDTVELARRV 166


>UniRef50_UPI0000E472BC Cluster: PREDICTED: similar to
           tRNA-dihydrouridine synthase; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to
           tRNA-dihydrouridine synthase - Strongylocentrotus
           purpuratus
          Length = 499

 Score =  183 bits (445), Expect = 4e-45
 Identities = 84/134 (62%), Positives = 106/134 (79%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++Y NK+ILAPMVRIGTLP RLLAL+YGADIVY +ELID+K L  +R  N +L TVDY+ 
Sbjct: 36  LSYANKVILAPMVRIGTLPTRLLALEYGADIVYCQELIDFKMLTCRRHVNRVLGTVDYIS 95

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGM 441
           + D  ++FRTC +E  ++V Q+GT D  RAL+VAK+VE DV+ IDINMGCPK+FS+KGGM
Sbjct: 96  KDD-VVIFRTCSKETDRLVFQMGTADAQRALRVAKMVEKDVSGIDINMGCPKDFSLKGGM 154

Query: 442 GVALLSKPDKAYQI 483
           G ALL KPD   +I
Sbjct: 155 GAALLQKPDTIKEI 168


>UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 402

 Score =  180 bits (437), Expect = 4e-44
 Identities = 89/164 (54%), Positives = 121/164 (73%), Gaps = 1/164 (0%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           M+Y NK I+APMVR+GT PMR+LA  YG DI Y+EELID K ++S R  N+ L T+D++ 
Sbjct: 28  MDYYNKKIMAPMVRVGTYPMRILAYNYGCDIAYSEELIDLKLMKSTRVVNEKLKTIDFIA 87

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGM 441
           + D T+ +RT E++ + V LQLGT     AL+ AK+V +D+ A+DINMGCPK FS++GGM
Sbjct: 88  K-DQTLCYRTSEKDVRNV-LQLGTASSMTALEAAKVVCNDICALDINMGCPKFFSVQGGM 145

Query: 442 GVALLSKPDKAYQILKTLVDNLS-IPVTCKIRILKTPEATLELV 570
           G ALLSKP+    IL TL  NL+ IP+TCKIR+L T + T++L+
Sbjct: 146 GSALLSKPETIKDILTTLKRNLNGIPITCKIRLLSTDQETIDLL 189


>UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 436

 Score =  173 bits (422), Expect = 3e-42
 Identities = 85/164 (51%), Positives = 112/164 (68%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           Y NK ILAPMVR G  P+RLL LKYGAD+ YTEE++D K + + R  N+ L T+DY +  
Sbjct: 5   YRNKKILAPMVRAGRTPLRLLCLKYGADLCYTEEIVDKKLIEATRVVNEALGTIDYRNGD 64

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
           D  I+ R   EEK + +LQ+GT    +A K+A++V  DVA ID+NMGCPK FSI  GMG 
Sbjct: 65  D--IILRLAPEEKGRCILQIGTNSGEKAAKIAQIVGDDVAGIDVNMGCPKPFSIHCGMGA 122

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
           ALL++ +K   IL +L     +PVTCKIR+L  PE TL+LV ++
Sbjct: 123 ALLTQTEKIVDILTSLKSAAKVPVTCKIRVLDDPEDTLKLVQEI 166


>UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 345

 Score =  169 bits (412), Expect = 4e-41
 Identities = 88/166 (53%), Positives = 112/166 (67%), Gaps = 2/166 (1%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           Y  K + APMVRI TL  RLLA +YGAD+VY EEL+D +F+  +R  N  L +VD++D  
Sbjct: 11  YTGKNVCAPMVRISTLATRLLAHEYGADLVYGEELVDKRFMHCRRILNKELGSVDFID-A 69

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
            GT+ FRT  EE+++VV Q+GT   A ALK A+LV  DVAAID+NMGCPK FS  GGMG 
Sbjct: 70  KGTLTFRTVPEERERVVFQVGTSSAASALKSAELVARDVAAIDVNMGCPKHFSTSGGMGA 129

Query: 448 ALLSKPDKAYQILKTLVDNL--SIPVTCKIRILKTPEATLELVNKL 579
            LLS+P+    IL TL  NL  +  VTCKIR+L++   T EL   +
Sbjct: 130 RLLSQPELVRDILTTLRRNLPSTTHVTCKIRLLESERETAELAKMI 175


>UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus2 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 479

 Score =  156 bits (379), Expect = 4e-37
 Identities = 78/173 (45%), Positives = 111/173 (64%), Gaps = 7/173 (4%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRS---KRRFNDILNTVD 252
           +NY NK+ LAPMVRIG LPMRLLAL+YGA++V+  E++D   L     +R  ND +N +D
Sbjct: 4   LNYSNKVCLAPMVRIGELPMRLLALRYGANLVWGPEIVDKALLSGTPVERVVNDRINCID 63

Query: 253 YVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIK 432
           +V      ++FR    E  +++ QLG+     A++ AKLV +DVA ID+N GCPK FS+ 
Sbjct: 64  FVKPPSNKVLFRVHPLEANRLIFQLGSASPELAVEAAKLVANDVAGIDLNCGCPKHFSVH 123

Query: 433 GGMGVALLSKPDKAYQILKTLVDNLSIP----VTCKIRILKTPEATLELVNKL 579
            GMG  LL   D+   IL  LV+ +  P    ++CKIR+L+T E TL+LV ++
Sbjct: 124 AGMGAGLLKNQDRLVSILDALVNEIGKPYKISISCKIRLLETKEDTLKLVERI 176


>UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 394

 Score =  155 bits (376), Expect = 1e-36
 Identities = 79/177 (44%), Positives = 112/177 (63%), Gaps = 11/177 (6%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++Y  K++LAPMVR G  P RLL++KYGAD+V++ E++D K L   R +N+   TVD+  
Sbjct: 2   VSYAGKLVLAPMVRSGEFPTRLLSIKYGADLVWSPEIVDKKMLECTREWNEKTKTVDFTV 61

Query: 262 QTDG-------TIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKE 420
              G        I+FRT E E+ K++ Q+G+ +   A+   K+V  DVA ID+N GCPK 
Sbjct: 62  SQQGKGNTEKKAIIFRTSEAERDKIIFQVGSANPEIAVAACKMVAKDVAGIDLNCGCPKH 121

Query: 421 FSIKGGMGVALLSKPDKAYQILKTLVDNLSIP----VTCKIRILKTPEATLELVNKL 579
           FS+  GMG ALL  PDK   IL+ LV  +  P    ++ KIR+L+T E TLELV++L
Sbjct: 122 FSMHAGMGAALLKTPDKLVAILEALVKEVGEPFNVSISVKIRLLETEEKTLELVDRL 178


>UniRef50_A7EHJ6 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Sclerotinia sclerotiorum 1980
          Length = 513

 Score =  152 bits (368), Expect = 1e-35
 Identities = 89/202 (44%), Positives = 121/202 (59%), Gaps = 19/202 (9%)
 Frame = +1

Query: 31  RFKTFIT*SILLQFPI---NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDW 201
           R  +FI  SI  + PI    ++Y  KI+LAPMVR G LP RLLAL YGAD+V+  E +D 
Sbjct: 82  RLTSFIMTSIPKKVPIPRKGVDYRGKIVLAPMVRSGELPSRLLALHYGADLVWGPETVDR 141

Query: 202 KFLRSKRRFNDILNTVDYVD-----------QTDGTIVFRTCEE-EKKKVVLQLGTCDEA 345
             + + R+ N  LNT+D+               + +++FR   E E KK++ Q+GT D  
Sbjct: 142 SMIGTTRKVNTALNTIDFTRLPSQGHKEKNANLNESLIFRLHPELEGKKLIFQIGTSDPE 201

Query: 346 RALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNL----SI 513
           +A++ A++V  DVA ID+N GCPK FS  GGMG ALL  PDK   IL+ LV  +     I
Sbjct: 202 KAVQCARMVAADVAGIDVNAGCPKPFSTSGGMGAALLQTPDKLCAILEALVKEIVPEFEI 261

Query: 514 PVTCKIRILKTPEATLELVNKL 579
            ++ KIR+L+TPE T  LV KL
Sbjct: 262 GISVKIRLLETPERTEALVRKL 283


>UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 496

 Score =  151 bits (367), Expect = 1e-35
 Identities = 72/167 (43%), Positives = 113/167 (67%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +NY+NK++LAPMVR G+LPMRLL+L YGA +V++ E++D   + ++R  + +   + Y  
Sbjct: 104 INYKNKLVLAPMVRTGSLPMRLLSLYYGAGLVWSPEVVDRAIIGAERSVDPVTGVITY-H 162

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGM 441
           +  G I F T   EK  ++ Q+G+ +   A+K A+ V+ DVA ID+N GCPK FS   GM
Sbjct: 163 KGQGPI-FSTHPAEKPFLIFQIGSSNPELAVKAAQTVQQDVAGIDLNCGCPKPFSTHAGM 221

Query: 442 GVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
           G ALLS P+    IL+ L+D++ +P++CKIR+L T  +TL L ++++
Sbjct: 222 GAALLSTPELLLDILRALLDSIPLPISCKIRLLPTQPSTLYLASRIL 268


>UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of
           strain CBS767 of Debaryomyces hansenii; n=1;
           Debaryomyces hansenii|Rep: Debaryomyces hansenii
           chromosome B of strain CBS767 of Debaryomyces hansenii -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 374

 Score =  150 bits (363), Expect = 4e-35
 Identities = 79/173 (45%), Positives = 112/173 (64%), Gaps = 7/173 (4%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           + Y  K+ LAPMVR G +P RL+AL+YGAD+V+T E++D K ++ +R  ND L TVD++D
Sbjct: 2   VEYSGKLALAPMVRSGEIPTRLMALRYGADLVWTPEIVDKKLIKCERVINDDLGTVDFLD 61

Query: 262 QTDGTIVFRTCE-EEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGG 438
                +VFRT   EE  K++ Q+G+ D   A++ AK+V  DV  ID+N GCPK FS   G
Sbjct: 62  PNK-KVVFRTYPAEELGKLIFQIGSADPELAVQAAKIVAQDVDGIDLNCGCPKPFSTHSG 120

Query: 439 MGVALLSKPDKAYQILKTLVDNL----SIPVTCKIRILKTPEAT--LELVNKL 579
           MG ALL+ PD    IL+ LV  +     IP++ KIR+L   + T  LEL+++L
Sbjct: 121 MGAALLTTPDLLELILRNLVSEVGKVYDIPISAKIRLLDDTDVTPSLELIDRL 173


>UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase;
           n=2; Saccharomycetales|Rep: Potential tRNA
           dihydrouridine synthase - Candida albicans (Yeast)
          Length = 433

 Score =  150 bits (363), Expect = 4e-35
 Identities = 78/176 (44%), Positives = 110/176 (62%), Gaps = 9/176 (5%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV- 258
           + Y NK+ LAPMVR G LP+RLL+L+YG D+++T EL+D K L+S R  N  LNT+DY+ 
Sbjct: 2   IEYANKLCLAPMVRSGELPIRLLSLRYGCDLLWTPELVDKKILQSTRIINQELNTIDYIV 61

Query: 259 ---DQTD-GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFS 426
               Q+D  T++FR    E  +++LQLG+ D   A+  A+ V  DV  ID+N GCPK FS
Sbjct: 62  SNHQQSDKKTVIFRKHPVETGRLILQLGSSDPQLAVDAARKVIDDVDGIDLNCGCPKNFS 121

Query: 427 IKGGMGVALLSKPDKAYQILKTLVDNLSIP----VTCKIRILKTPEATLELVNKLI 582
              GMG  LL  PDK   IL  LV+ + IP    ++CKIR+    + +  L+ K++
Sbjct: 122 THSGMGAELLKTPDKLCSILINLVEKIGIPNKKSISCKIRLFNNYDQSKNLIEKIL 177


>UniRef50_P53720 Cluster: tRNA-dihydrouridine synthase 2; n=7;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 2 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 384

 Score =  147 bits (356), Expect = 3e-34
 Identities = 85/176 (48%), Positives = 113/176 (64%), Gaps = 10/176 (5%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           + Y  K++LAPMVR G LP RL+AL +GAD+V++ E+ID K ++  R+ N  L TVDYV 
Sbjct: 2   VTYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCVRKENTALQTVDYVV 61

Query: 262 ----QT-DGTIVFRTCEE-EKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEF 423
               QT   T+VFRT  + E  K++ Q+G+   A A + A  V +DV+ IDIN GCPK F
Sbjct: 62  PSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHF 121

Query: 424 SIKGGMGVALLSKPDKAYQILKTLVDNL----SIPVTCKIRILKTPEATLELVNKL 579
           SI  GMG ALL  PD    ILK LV N+    S P++ KIR+L T + TL+LV +L
Sbjct: 122 SIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRL 177


>UniRef50_A5DYF6 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 504

 Score =  143 bits (346), Expect = 4e-33
 Identities = 78/180 (43%), Positives = 107/180 (59%), Gaps = 14/180 (7%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV- 258
           + Y NK+ LAPMVR G LP+RLLAL+YG D+V++ E ID K ++++RR N  LNT+DY+ 
Sbjct: 7   LTYTNKVCLAPMVRSGELPIRLLALRYGCDLVWSPEYIDRKIIQTQRRVNAELNTIDYII 66

Query: 259 ---------DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGC 411
                          +VFR   EE  K++ QLGT     A++ A  V  DV  ID+N GC
Sbjct: 67  PNNKDPSKMKHNQDNVVFRKHPEETGKLIFQLGTSTPELAVEAALRVIEDVDGIDLNCGC 126

Query: 412 PKEFSIKGGMGVALLSKPDKAYQILKTLVDNL----SIPVTCKIRILKTPEATLELVNKL 579
           PK FS  GGMG  LL  PD    IL+ LV+ +      P++CKIR+L   EA+  L+ ++
Sbjct: 127 PKSFSTHGGMGAELLKTPDILCSILRALVEKVGNPNKKPISCKIRLLPNFEASKLLIEQI 186


>UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12;
           Pezizomycotina|Rep: Contig An02c0390, complete genome -
           Aspergillus niger
          Length = 446

 Score =  140 bits (338), Expect = 4e-32
 Identities = 81/186 (43%), Positives = 109/186 (58%), Gaps = 16/186 (8%)
 Frame = +1

Query: 73  PIN-MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTV 249
           P N ++Y  K++LAPMVR G LP RL+ALKYGAD+V+  E ID     + RR N    T+
Sbjct: 13  PANGVDYRGKVVLAPMVRSGELPSRLIALKYGADLVWGPETIDRAMAGAIRRVNPRNGTI 72

Query: 250 DYVDQTDG----------TIVFRTCE-EEKKKVVLQLGTCDEARALKVAKLVEHDVAAID 396
           ++                ++++R     EK K++ Q+GT     A++ AKLV  DVA ID
Sbjct: 73  EFTRMPSNGGRTEKAGQESVIYRLDPVREKGKLIYQIGTATPEIAVQAAKLVAGDVAGID 132

Query: 397 INMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIP----VTCKIRILKTPEATLE 564
           +N GCPK FS  GGMG ALL  PDK   IL+ LV  +  P    ++ KIRILK PE T  
Sbjct: 133 VNSGCPKPFSTSGGMGAALLKTPDKLVAILEALVKEVGTPFQIGISVKIRILKDPEETRA 192

Query: 565 LVNKLI 582
           LV++L+
Sbjct: 193 LVSRLV 198


>UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 766

 Score =  133 bits (321), Expect = 5e-30
 Identities = 74/171 (43%), Positives = 101/171 (59%), Gaps = 4/171 (2%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           + Y N I LAPMVRIGTLP RLL+L+YGAD+V+  E++D   +  +R+ N     V+Y+ 
Sbjct: 72  LEYRNGIFLAPMVRIGTLPTRLLSLEYGADLVWGPEIVDRAIIGCERKVNPHTGVVEYL- 130

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH--DVAAIDINMGCPKEFSIKG 435
             D   +F     E+  +V QLG+ D   A +  K +    DVAA+D+N GCPK FS   
Sbjct: 131 -KDHKQIFSCHPIERPYLVYQLGSADPHLAFQAIKTITQADDVAAVDLNCGCPKPFSTHA 189

Query: 436 GMGVALLSKPDKAYQILKTL--VDNLSIPVTCKIRILKTPEATLELVNKLI 582
           GMG  +LS P      LK +       + VTCKIR+L T E TLELV+K++
Sbjct: 190 GMGANMLSTPILLCNTLKAMRRAAPAHVAVTCKIRLLPTQEKTLELVDKIV 240


>UniRef50_Q1DPY5 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 453

 Score =  132 bits (319), Expect = 8e-30
 Identities = 72/181 (39%), Positives = 110/181 (60%), Gaps = 15/181 (8%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDY-- 255
           ++Y  KI+LAPMVR G  P R+++LKYGAD+V+  E +D   + +KRR N   + ++Y  
Sbjct: 18  VDYRGKIVLAPMVRSGETPSRIVSLKYGADLVWGPETVDRAIIGAKRRINPRNSMIEYTR 77

Query: 256 VDQTDG--------TIVFRTCE-EEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMG 408
           +    G        ++++R     E+ K++ QLGT + + A++ AK+V  DV+ ID+N G
Sbjct: 78  IPSNGGQPNKPAQESVLYRIDPVRERGKLIFQLGTANPSLAVEAAKVVAADVSGIDVNSG 137

Query: 409 CPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIP----VTCKIRILKTPEATLELVNK 576
           CPK FS  GGMG ALL  PD+   IL+ LV+ +  P    ++ KIR+L  PE T  LV +
Sbjct: 138 CPKPFSTSGGMGAALLQTPDRLVSILEALVEEIGKPYEIGISVKIRLLAEPERTEALVTR 197

Query: 577 L 579
           +
Sbjct: 198 V 198


>UniRef50_A6R3V4 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 461

 Score =  126 bits (305), Expect = 4e-28
 Identities = 77/182 (42%), Positives = 105/182 (57%), Gaps = 16/182 (8%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           MN++   +LAPMVR G LP RLLALKYGAD+V+  E ID   +   RR N   + V++  
Sbjct: 1   MNHQR--VLAPMVRSGELPSRLLALKYGADLVWGPETIDRALIGCTRRINPRNSMVEFTR 58

Query: 262 -QTDG----------TIVFRTC-EEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINM 405
             ++G          +I++R     E  K+V Q+GT     A++ AK++  DVA ID+N 
Sbjct: 59  LPSNGGRENNQAAKESIIYRLDPHRESGKLVFQIGTASPDLAVQAAKIIAADVAGIDVNA 118

Query: 406 GCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIP----VTCKIRILKTPEATLELVN 573
           GCPK FS  GGMG ALL  PD+   IL  LV  +  P    ++ KIR+L  PE T +LV 
Sbjct: 119 GCPKPFSTTGGMGAALLQTPDRLVSILTALVQQVGTPYQIGISVKIRLLADPERTRDLVT 178

Query: 574 KL 579
           +L
Sbjct: 179 RL 180


>UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 313

 Score =  105 bits (252), Expect = 1e-21
 Identities = 56/165 (33%), Positives = 93/165 (56%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           Y+NK+I APMVR  +L  RL  L+YGAD+V++  L+D   + S    +D   ++  V+  
Sbjct: 9   YKNKLIAAPMVRGSSLSFRLACLEYGADLVFSPGLVDLAIIGSTMEKDDNNISLIKVENG 68

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
               +F T  EE+ K+++QL T D   A+K A +     + IDIN GCP+ F+   G G 
Sbjct: 69  HNRRIFHTTAEERGKLIIQLITVDGPNAIKAADMCTEFASGIDINCGCPESFACHRGGGS 128

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
            +  + + A  ++KTL  N  +P++ K+R+  T E +L+    ++
Sbjct: 129 KM--QLESAVDVVKTLKMNSPLPISVKMRVKDTVEESLQFAKAMV 171


>UniRef50_Q38BB4 Cluster: TRNA-dihydrouridine synthase 2, putative;
           n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 2,
           putative - Trypanosoma brucei
          Length = 435

 Score =   99 bits (238), Expect = 5e-20
 Identities = 66/189 (34%), Positives = 97/189 (51%), Gaps = 28/189 (14%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFN----------DI 237
           +  K ILAPMVR+GT+  R+     GADIV++EE++  K +R KR             + 
Sbjct: 4   FNGKTILAPMVRVGTVGFRVFCAAQGADIVFSEEVVASKLIRCKREVRTYTGCPCSMVEF 63

Query: 238 LNTVDYVDQTDGTIVFRT-----CEE--EKKKVVLQLGTCDEARALKVAKLVEHDVAAID 396
           ++   Y ++   +I F T     C    E   VVLQLG  + A   + A L   DV  ID
Sbjct: 64  VSYEPYKNKFKRSIAFATVARGGCNSQGEGAPVVLQLGVAEPAIGARAALLCVDDVDGID 123

Query: 397 INMGCPKEFSIKGGMGVALLSKPDKAYQIL-----------KTLVDNLSIPVTCKIRILK 543
           +NMGCPK+FS+  GMG AL+  P +A  IL           K +     +P++ K R+L 
Sbjct: 124 VNMGCPKKFSVDNGMGAALMRDPARAAAILVAVDEAVNSPEKVVARRRRVPISFKTRLLD 183

Query: 544 TPEATLELV 570
           T +AT +++
Sbjct: 184 TADATAQML 192


>UniRef50_Q24833 Cluster: Putative nitrogen fixation regulatory
           protein-3 homologue; n=3; Entamoeba histolytica|Rep:
           Putative nitrogen fixation regulatory protein-3
           homologue - Entamoeba histolytica
          Length = 165

 Score = 96.7 bits (230), Expect = 5e-19
 Identities = 57/144 (39%), Positives = 83/144 (57%)
 Frame = +1

Query: 148 LALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVFRTCEEEKKKVVLQL 327
           +AL  GA  V+TEEL+  +    KR  N     + Y+ + D  +  +   E++ K +LQL
Sbjct: 1   MALDAGASAVFTEELVSKRLCECKRVENS--GIIQYIHKNDVMLTLKP--EQQSKTILQL 56

Query: 328 GTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNL 507
           GT D   ++K   L++ +V  IDIN+GC   FS KG MG AL+   DK  +I+K LV  L
Sbjct: 57  GTFDVESSVKCVSLIQ-EVCGIDINLGCGMWFSTKGEMGQALVDNRDKLEKIVKALV-GL 114

Query: 508 SIPVTCKIRILKTPEATLELVNKL 579
           S P++ KIR+ +T E TLE +  L
Sbjct: 115 SKPISAKIRLQQTHEETLEFIQWL 138


>UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 333

 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 52/159 (32%), Positives = 84/159 (52%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           Y  KI   PMVR   LP RL+ L+ GAD VY         L S    N+   T+ +    
Sbjct: 9   YRGKIFAGPMVRASNLPFRLMCLENGADGVYGPATSVDSILASHYDENEDPYTMYFGWPK 68

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
           +  + F T  +EK K++ Q+ T D ++A++ A +V     AID+N GCP+ F+   G G 
Sbjct: 69  NPHVHFHTDPKEKGKLIFQILTNDASKAVQAASVVVKFADAIDLNCGCPESFATSRGTGS 128

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLE 564
           +L+S+P+    ++  L  N ++P++ K RI    E +++
Sbjct: 129 SLMSEPEIVADVVSALRRNYNVPISVKHRIHHNIEESIQ 167


>UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, whole
           genome shotgun sequence; n=4; Intramacronucleata|Rep:
           Chromosome undetermined scaffold_94, whole genome
           shotgun sequence - Paramecium tetraurelia
          Length = 360

 Score = 86.2 bits (204), Expect = 7e-16
 Identities = 57/161 (35%), Positives = 80/161 (49%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           K I APMV    L  R+L  KYG  + YT  L       SK           Y D+    
Sbjct: 19  KFICAPMVDQSELAFRMLTRKYGTTLAYTPMLHSRIMTESK----------SYKDE---- 64

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
             F TC E++  +  QL   D    +K A +++    AIDIN+GCP+  + KG  G  LL
Sbjct: 65  -FFTTCPEDRP-LFAQLCGHDPQVLIKAALMIQDQCDAIDINLGCPQGIARKGLYGAYLL 122

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
            K ++   I+K L  N+++PVTCKIR+ K  + TL+L   +
Sbjct: 123 EKREQVLTIVKELKQNINVPVTCKIRMFKDRKRTLDLTKDI 163


>UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 339

 Score = 82.6 bits (195), Expect = 9e-15
 Identities = 47/159 (29%), Positives = 83/159 (52%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           ILAPMV    L  R+L  ++G ++ YT  ++   F+ SK   N+++N++D  +Q      
Sbjct: 25  ILAPMVDGSDLTFRILVRRHGVNLCYTPMVLSKMFVESKVYRNEVVNSLDPKEQP----- 79

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
                     +++Q+   D     + AK ++    AIDIN+GCP++ + KG  G  L   
Sbjct: 80  ----------IIIQIVGSDANEMARTAKFLQSYCDAIDINLGCPQKIAQKGNYGAYLALD 129

Query: 463 PDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
            D   +I+  +++ ++IPV CK+R+ +  E T+  V  L
Sbjct: 130 FDHTKEIVNAVIEAVNIPVYCKVRVFEDEEKTMRFVEML 168


>UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=2;
           Cryptosporidium|Rep: Dus1p, tRNA dihydrouridine synthase
           - Cryptosporidium parvum Iowa II
          Length = 409

 Score = 82.6 bits (195), Expect = 9e-15
 Identities = 56/164 (34%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           K +LAPMV    L  RL+  KYG D+ Y           S    + + + +    +T+  
Sbjct: 20  KTVLAPMVDGSELAFRLICKKYGCDLGY-----------SPMYHSGLFSKLQGYRETN-- 66

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
             F+TCEE+   +V   G  D    +K +K ++  V  IDIN GCP+  + +G  G  LL
Sbjct: 67  --FQTCEEDDPMIVQFCGN-DPETLVKASKFIDDKVKGIDINFGCPQNIAKRGNYGAFLL 123

Query: 457 SKPDKAYQILKTLVD-NLSIPVTCKIRIL--KTPEATLELVNKL 579
           S PD   +I+ TL + +L  PV+CKIRIL     + T+ L+ +L
Sbjct: 124 SNPDLMERIISTLSESDLKCPVSCKIRILDHHDLQPTINLIKRL 167


>UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep:
           Gb|AAF51525.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 423

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 58/161 (36%), Positives = 78/161 (48%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           K I+APMV    LP RLL  KYGA   YT  L         R F +   T  Y +Q    
Sbjct: 89  KYIVAPMVDNSELPFRLLCQKYGAQAAYTPML-------HSRIFTE---TEKYRNQE--- 135

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
             F TC+E++   V Q    D    L+ AK VE     +DIN+GCP+  + +G  G  L+
Sbjct: 136 --FTTCKEDRPLFV-QFCANDPDTLLEAAKRVEPYCDYVDINLGCPQRIARRGNYGAFLM 192

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
                   +++ L  NL++PV+CKIRI    E TL+    L
Sbjct: 193 DNLPLVKSLVEKLAQNLNVPVSCKIRIFPNLEDTLKYAKML 233


>UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 671

 Score = 80.6 bits (190), Expect = 4e-14
 Identities = 54/160 (33%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +N+EN++ILAP+  +G LP R +  + GADI   E  +  K L   +    +L       
Sbjct: 320 INFENQLILAPLTTVGNLPFRRICKRLGADITIGEMALTTKLLEGTKSELALLKR----- 374

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIKG 435
                     CE+  K  V   G+  +A A+K A+ +E+++ A  +DIN GCP +     
Sbjct: 375 --------HPCED--KFGVQICGSYVDA-AVKCAEFIENEIDADFVDINSGCPIDLVCNM 423

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEA 555
           G G AL+ +P K  Q+L+ +  +LS P T KIRI K+ +A
Sbjct: 424 GAGAALMERPKKVEQLLRGISSSLSCPTTIKIRIGKSEDA 463


>UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 344

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 49/158 (31%), Positives = 82/158 (51%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           I APMVR   LP R+L  K+G DI YT  ++  +F RS+    D   T++ +D+      
Sbjct: 58  IQAPMVRFSRLPFRMLVKKWGCDITYTPMIMAAEFNRSEAA-RDSDFTINKLDEP----- 111

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
                     +++Q G  +    +  A+ V+     IDIN GCP+ + +K G G  LL  
Sbjct: 112 ----------LIVQFGVNNAEELVSAAEKVKDYCQGIDINCGCPQRWVMKEGFGANLLLH 161

Query: 463 PDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNK 576
           P++ Y ++K + + + IP++ KIR+    + T+EL  +
Sbjct: 162 PERIYDMVKQINNRVPIPISIKIRVQSDLKDTIELAKR 199


>UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep:
           NifR3-like protein - Methanosarcina mazei
           (Methanosarcina frisia)
          Length = 323

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 53/157 (33%), Positives = 82/157 (52%), Gaps = 1/157 (0%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEEL-IDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           ++LAPM  +  L  RLL  +YGAD+ YTE + +D     S++ F   L++ +  D+  G 
Sbjct: 17  LLLAPMADVTNLAFRLLCRRYGADLTYTEMINVDALLNESRKSFIKGLSSEE--DRPFGV 74

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
            +   C ++ K+  L +   +E          E+    ID+NMGCP       G G ALL
Sbjct: 75  QLVGGCPDKLKRAALFI---EE----------EYRPEIIDVNMGCPARCITGAGCGSALL 121

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLEL 567
           + P+  Y I+  L ++L  PV+ KIR+L   E TLE+
Sbjct: 122 NSPELVYSIILELTESLDTPVSAKIRLLGREEKTLEI 158


>UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase;
           n=2; Saccharomycetales|Rep: Potential tRNA
           dihydrouridine synthase - Candida albicans (Yeast)
          Length = 339

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 52/162 (32%), Positives = 83/162 (51%), Gaps = 2/162 (1%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           I  PMVR   LP R L   Y  DIVYT  ++  +F+R     N++  + D+         
Sbjct: 29  IAGPMVRYSKLPFRELCRFYDVDIVYTPMILAREFVR-----NEVARSTDF--------- 74

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
             T  +  K V++Q+G  +    +K  +++   V  I IN GCP +  ++ G+G AL+S 
Sbjct: 75  --TTNDSDKCVIVQVGVNNVDDFMKFIEMIHPFVDGIGINCGCPIKEQVREGIGAALMSD 132

Query: 463 PDKAYQILKTLVDNL--SIPVTCKIRILKTPEATLELVNKLI 582
           PD   +++KT  D    SI +  KIRI +    T++ VNK++
Sbjct: 133 PDLVAELIKTAKDKYGDSICIDTKIRIHRDINQTIDFVNKVV 174


>UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 435

 Score = 79.4 bits (187), Expect = 8e-14
 Identities = 55/171 (32%), Positives = 83/171 (48%)
 Frame = +1

Query: 67  QFPINMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNT 246
           +F  N+    K  +APMV    L  R+L  KYGAD+VYT       F   K    D    
Sbjct: 43  EFFRNVLKSPKKTVAPMVDHTFLAFRMLCRKYGADMVYTPMFHSKNFATCKTYRRD---- 98

Query: 247 VDYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFS 426
                       + TC E++  VV   G  +    +K AK +E    AID+N+GCP++ +
Sbjct: 99  -----------YWSTCPEDRPLVVQFCGN-EPEWVVKAAKYIEDHCDAIDLNLGCPQQIA 146

Query: 427 IKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
            +G  G  LL KP     I++ L  ++ +P+ CKIR+L   + T++L  +L
Sbjct: 147 RRGNYGSFLLDKPHIILPIVQELHKHIKVPIFCKIRLLPNLDDTIKLALQL 197


>UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 1 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 423

 Score = 79.4 bits (187), Expect = 8e-14
 Identities = 55/160 (34%), Positives = 81/160 (50%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           I+APMV    L  R+L+ +YGA + YT  L    F  SK+   D  +++D      G+ V
Sbjct: 32  IVAPMVDQSELAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLD------GSSV 85

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
            R        +V+Q    D    L  AKLVE    A+D+N+GCP+  + KG  G  L+ +
Sbjct: 86  DRP-------LVVQFCANDPEYLLAAAKLVEDKCDAVDLNLGCPQGIAKKGHYGSFLMEE 138

Query: 463 PDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
            D  + ++ TL  NL +PVT KIRI    E +L     ++
Sbjct: 139 WDLIHNLINTLHKNLKVPVTAKIRIFDDCEKSLNYAKMVL 178


>UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus4 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 326

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 58/169 (34%), Positives = 81/169 (47%), Gaps = 2/169 (1%)
 Frame = +1

Query: 70  FPINMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTV 249
           F IN       I APMVR   LP R L   Y  DIVYT  ++  +FL  K R+ D     
Sbjct: 12  FEINKGKRPVHIAAPMVRYSKLPFRQLVRDYNTDIVYTPMILAKEFLHPKGRYFD----- 66

Query: 250 DYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSI 429
                      F T + +   ++LQ G  D     K A+LV   V  I IN GCP+ ++I
Sbjct: 67  -----------FSTNDADAS-LILQFGVDDPVILEKAAQLVGPYVDGIGINCGCPQTWAI 114

Query: 430 KGGMGVALLSKPDKAYQILKTLVDNL--SIPVTCKIRILKTPEATLELV 570
           + G+G ALL +P+K +++++ +   L  S     KIRI K    T  L+
Sbjct: 115 QEGIGSALLDEPEKVHKLVRAVKSTLGESFCTEVKIRIAKDLNKTRHLM 163


>UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus1 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 399

 Score = 76.2 bits (179), Expect = 8e-13
 Identities = 55/162 (33%), Positives = 77/162 (47%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           K ILAPMV    LP R+LA + GAD+ Y+       F  S+   N + +T          
Sbjct: 19  KRILAPMVDQSELPWRILARRSGADLCYSPMFHSRLFGESEDYRNKVFST---------- 68

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
              RT  EE+  ++   G  D    LK AK+      A+D+N+GCP+  + KG  G  L 
Sbjct: 69  ---RTIPEERPLIIQFCGN-DPEIMLKAAKIAAPYCDAVDVNLGCPQGIAKKGKYGSFLQ 124

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
              +    I+  L   LSIPVT KIRI   P+ TL+    ++
Sbjct: 125 ENWNLIESIITKLHTELSIPVTAKIRIFPDPQKTLDYAKMIL 166


>UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=8; Desulfuromonadales|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Geobacter sp. FRC-32
          Length = 343

 Score = 72.9 bits (171), Expect = 7e-12
 Identities = 52/152 (34%), Positives = 76/152 (50%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           ++  EN +ILAPM  +  LPMR+LA + GA + +TE +     +R  ++  D+L   D +
Sbjct: 26  SLQLENNLILAPMAGLTNLPMRILARECGAALTFTEMISVNGLVREGKKTFDLLRR-DPM 84

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGG 438
           D+  G  +F                 D     + A+LVE     IDINMGCP    +  G
Sbjct: 85  DRPMGIQIFGD---------------DPQLLAEGARLVEQYGELIDINMGCPVRKVVGSG 129

Query: 439 MGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
            G ALL +P K   I+K +    S+P+T KIR
Sbjct: 130 AGSALLREPAKVGMIIKAVRKATSLPLTIKIR 161


>UniRef50_A3AVU4 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 190

 Score = 72.9 bits (171), Expect = 7e-12
 Identities = 32/51 (62%), Positives = 41/51 (80%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFND 234
           M Y +K++LAPMVR+GTLP RLLA +YGADI Y EE+ID KFL+ +R  N+
Sbjct: 1   MEYRDKLVLAPMVRVGTLPFRLLAAEYGADITYGEEIIDHKFLKCERVTNE 51


>UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative;
           n=5; Plasmodium|Rep: tRNA-dihydrouridine synthase,
           putative - Plasmodium vivax
          Length = 340

 Score = 72.9 bits (171), Expect = 7e-12
 Identities = 43/146 (29%), Positives = 74/146 (50%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           K ILAPMV +  L  RLL   Y   + +T  L    F+  ++                  
Sbjct: 27  KHILAPMVDLSELAFRLLCRNYNCHLTFTPMLHAKNFVEHEKYRKS-------------- 72

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
             F++CE++ + V+ Q    +    L   + ++++V A+D+N+GCP++ + KG  G  LL
Sbjct: 73  -YFQSCEKD-EPVIAQFCGNNSKIILNAIEYIKNEVNAVDLNLGCPQQIAKKGNYGAFLL 130

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIR 534
            K D+   ++  + +N +IP+TCKIR
Sbjct: 131 QKHDEVVNLVSDITNNCNIPITCKIR 156


>UniRef50_Q4Q231 Cluster: Dihydrouridine synthase domain
           protein-like protein; n=3; Leishmania|Rep:
           Dihydrouridine synthase domain protein-like protein -
           Leishmania major
          Length = 455

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 60/195 (30%), Positives = 95/195 (48%), Gaps = 35/195 (17%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKR---RFNDILNTV-DYVDQTD 270
           ILAPMVR+ +   R L   +GAD+V+TEE++  K    +R   R+  +   + +YV    
Sbjct: 28  ILAPMVRVCSPGFRALCGAHGADVVFTEEVVAAKLATCQREVVRYPTVDTPMAEYVSYDP 87

Query: 271 ------GTIVFRTC-------------EEEKKKVVLQLGTCDEARALKVAKLVEHDVAAI 393
                  T+V  T                   + VLQLG  D AR    A +  +D+  I
Sbjct: 88  FKHTYKRTVVLSTPVLPDTTYGGQKADRISAPRTVLQLGVADPARGAAAALVCSNDIDGI 147

Query: 394 DINMGCPKEFSIKGGMGVALLSKPDKAYQILKTL---VDNLS---------IPVTCKIRI 537
           DINMGCPK+FS+  G G AL+ +P+    I++ +   V++ S         + V+ K R+
Sbjct: 148 DINMGCPKKFSVHNGFGAALMKRPEVGGAIVRAVHGAVNSDSNVEARGGKRVAVSLKTRL 207

Query: 538 LKTPEATLELVNKLI 582
             T EAT+ ++  ++
Sbjct: 208 QDTAEATVGMLRAIL 222


>UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein
           ECU07_1610; n=1; Encephalitozoon cuniculi|Rep: Putative
           uncharacterized protein ECU07_1610 - Encephalitozoon
           cuniculi
          Length = 341

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 50/153 (32%), Positives = 75/153 (49%)
 Frame = +1

Query: 106 LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVF 285
           +APMV       R L+ ++GA+I YTE +    FLR  R  N + N      + D  +V 
Sbjct: 15  VAPMVGNSEEAWRRLSKRHGANIFYTEMVHCDSFLRGSR--NPVKNRWYTTSEGDRPLVV 72

Query: 286 RTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKP 465
           + C           G   E   L+ A +++    AID+N GCP++ + KGG G  L    
Sbjct: 73  QIC-----------GNSPEVM-LEAALIIQDHCDAIDVNFGCPQKVARKGGYGAYLQENW 120

Query: 466 DKAYQILKTLVDNLSIPVTCKIRILKTPEATLE 564
               +I+K L   L++PV CKIR+  + E T+E
Sbjct: 121 KLTGEIVKVLSSGLNVPVFCKIRVFGSIEKTVE 153


>UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 527

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 43/166 (25%), Positives = 83/166 (50%), Gaps = 13/166 (7%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEEL-----IDWKFLRSKRRFNDILNTVDYVDQT 267
           ++APMV    L  R+L+ +YG+D+VYT  +      D    + K ++ ++    ++ ++ 
Sbjct: 52  VVAPMVDQSELAWRILSRRYGSDLVYTPMINAKLFADENSKKKKVKYQEVNFNREHAEEG 111

Query: 268 DGTIVFRTCEEE--------KKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEF 423
             + +      E         + + +Q  + D    LK AK+VE    A+D+N+GCP+  
Sbjct: 112 ASSPIASLLSNEGEGSSKDTDRPLFVQFCSNDPETLLKAAKVVEDRCDAVDLNLGCPQHI 171

Query: 424 SIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATL 561
           + +G  G  L+      + ++  L  NL +PVT K+R+ ++ E T+
Sbjct: 172 ARRGHYGSYLMEDWSLIFSLINILHVNLKVPVTAKMRVYESVEKTI 217


>UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2;
           Cystobacterineae|Rep: TRNA-dihydrouridine synthase B -
           Stigmatella aurantiaca DW4/3-1
          Length = 369

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 50/148 (33%), Positives = 74/148 (50%), Gaps = 1/148 (0%)
 Frame = +1

Query: 94  NKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           N  ILAPM  +   P R++A K+GA +  TE +     +R+ +R      T+ Y+     
Sbjct: 43  NPYILAPMAGVSERPFRVIAFKWGAALCPTELVSAQGLMRANQR------TLKYL----- 91

Query: 274 TIVFRTCEEEKKKVVLQL-GTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVA 450
               R   E ++   LQ+ G   EA A        H    IDINMGCP +   K G G A
Sbjct: 92  ----RFSPEVERPYSLQIFGGEPEAMAQAALVGKAHGAQIIDINMGCPVKKVTKNGAGSA 147

Query: 451 LLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           L+ +P +A +I++ + +   +PVTCKIR
Sbjct: 148 LMCEPLRAARIVQAIAEATGLPVTCKIR 175


>UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep:
           CG3645-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 505

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 47/161 (29%), Positives = 76/161 (47%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           + ++APMV    L  R+L  +YGA++ Y+       F    +   D L            
Sbjct: 29  RYVVAPMVDQSELAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDAL------------ 76

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
              +TC E++  ++   G  D  + L  A L +    A+DIN+GCP+  + +G  G  L 
Sbjct: 77  ---QTCPEDRPLIIQFCGN-DAQQILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQ 132

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
            + +   +I+ TL   L++PVTCKIRI +  E T+     L
Sbjct: 133 DEWELLTEIVSTLHAKLAVPVTCKIRIFEDLEKTIRYAKML 173


>UniRef50_Q2H6D9 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 464

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 34/82 (41%), Positives = 48/82 (58%)
 Frame = +1

Query: 337 DEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIP 516
           D    L  AK+      A+D+N+GCP+  + KG  G  L    D  +Q++K L +NL IP
Sbjct: 120 DPQALLNAAKIAAPYCDAVDLNLGCPQGIAKKGHYGSFLQEDQDLIHQLIKILHENLDIP 179

Query: 517 VTCKIRILKTPEATLELVNKLI 582
           VT KIRIL+T EATL+    ++
Sbjct: 180 VTAKIRILETKEATLKYAQNVL 201


>UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17;
           Pasteurellaceae|Rep: tRNA-dihydrouridine synthase B -
           Pasteurella multocida
          Length = 332

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 48/149 (32%), Positives = 73/149 (48%), Gaps = 1/149 (0%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           +N+I LAPM  I   P R +   YGA + ++E                +++T   V  T+
Sbjct: 9   KNRIFLAPMAGITDQPFRRICTHYGAGLTFSE----------------MMSTNPQVWHTE 52

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKL-VEHDVAAIDINMGCPKEFSIKGGMGV 447
            + +     +E     +Q+  CD     K A++ VE+    IDINMGCP +   +   G 
Sbjct: 53  KSKLRLAHHQEAGINAVQIAGCDPDEMAKAAQINVEYGAEIIDINMGCPAKKVNRKMAGS 112

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           ALL  PD   QIL  +V ++++PVT KIR
Sbjct: 113 ALLQYPDLVKQILNKVVKSVTVPVTLKIR 141


>UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep:
           Lmo0227 protein - Listeria monocytogenes
          Length = 331

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 51/169 (30%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           N+  +N++++APM  I     RL   ++GA +V  E + D        +  D+L    Y+
Sbjct: 6   NVEIKNQVVVAPMAGISNSAFRLTVKEFGAGLVCCEMISDKGIAYRNAKTLDML----YI 61

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIK 432
           D            E++K + LQ+   ++   ++ AK V  +  A  IDINMGCP    IK
Sbjct: 62  D------------EKEKPLSLQIFGGEKETLVEAAKFVAENTTADIIDINMGCPVNKIIK 109

Query: 433 GGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
              G   L  P+K Y ++  +VD +  PVT K+RI    E    + N L
Sbjct: 110 CEAGAKWLLDPNKVYDMVAAVVDAVDKPVTVKMRIGWDEEHVFAIENAL 158


>UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative;
           n=2; Trypanosoma cruzi|Rep: Dihydrouridine synthase
           (Dus), putative - Trypanosoma cruzi
          Length = 548

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 49/172 (28%), Positives = 77/172 (44%), Gaps = 13/172 (7%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           ++ PMV    LP R+L  +YGA + Y+  L    F +S +      +T  +  +   T  
Sbjct: 99  VVGPMVDQSELPFRMLCRRYGATLAYSPMLHARSFAQSAQYRARYFSTTPHRAELAMTAT 158

Query: 283 F-----------RTCEEEKKKVVLQLGTC--DEARALKVAKLVEHDVAAIDINMGCPKEF 423
                       RT + E+    L +  C  D    L  A+ VE D  A+D+N+GCP+  
Sbjct: 159 ASGEGEAAEDAGRTSDGEETDHPLFVQFCGNDADTLLAAARHVEDDCEAVDVNLGCPQGI 218

Query: 424 SIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
           + +G  G  L+   D+ + IL  L   L +PVT K+R+      TL+    L
Sbjct: 219 ARRGHYGSFLMEDWDRVHNILHCLAVELRVPVTAKMRVFDDDALTLKYAEML 270


>UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1;
           Babesia bovis|Rep: Dihydrouridine synthase, putative -
           Babesia bovis
          Length = 355

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 42/146 (28%), Positives = 73/146 (50%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           + + APMV    LP RLL  +Y  D+ YT  L    F+ +++                  
Sbjct: 13  RYVAAPMVNQSELPFRLLCRRYNVDLTYTPMLHGRIFVENEKY---------------RA 57

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
           + F+T +++ + ++ Q+   D     + A+L++  V+A+D+N+GCP+  +  G  G  LL
Sbjct: 58  VHFQTSDDD-RPLIAQVCGDDAGTITQAARLLKGHVSAVDLNLGCPQAIAKDGHYGSFLL 116

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIR 534
            +PD    I+  +   + I VTCKIR
Sbjct: 117 DEPDLVTGIVSRVTREVGIAVTCKIR 142


>UniRef50_Q7RX85 Cluster: Putative uncharacterized protein
           NCU00065.1; n=3; Pezizomycotina|Rep: Putative
           uncharacterized protein NCU00065.1 - Neurospora crassa
          Length = 629

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 40/111 (36%), Positives = 57/111 (51%)
 Frame = +1

Query: 250 DYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSI 429
           DYV   DG   F       + + +Q    D A  L  AKLV     A+D+N+GCP+  + 
Sbjct: 122 DYVPFLDGNPEF------DRSLFVQFCANDPAYLLSAAKLVAPYCDAVDLNLGCPQGIAK 175

Query: 430 KGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
           +G  G  L    +  ++++ TL   L IPVT KIRIL T EATL+    ++
Sbjct: 176 RGQYGSFLQENQELIFELINTLHKELDIPVTAKIRILDTKEATLKYAQNVL 226


>UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1;
           n=31; Bacilli|Rep: Probable tRNA-dihydrouridine synthase
           1 - Bacillus subtilis
          Length = 333

 Score = 66.1 bits (154), Expect = 8e-10
 Identities = 47/155 (30%), Positives = 77/155 (49%), Gaps = 2/155 (1%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           ++  +N+++LAPM  +     RL   ++GA +V  E + D   L +  R   +L    Y+
Sbjct: 6   DIQLKNRVVLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILYNNARTMGML----YI 61

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIK 432
           D            E +K + LQ+    +   ++ AK V+ +  A  IDINMGCP     K
Sbjct: 62  D------------EREKPLSLQIFGGKKETLVEAAKFVDQNTTADIIDINMGCPVPKITK 109

Query: 433 GGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
              G   L  PDK Y+++  +VD ++ PVT K+R+
Sbjct: 110 CDAGAKWLLDPDKIYEMVSAVVDAVNKPVTVKMRM 144


>UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5;
           Firmicutes|Rep: TRNA-dihydrouridine synthase -
           Pelotomaculum thermopropionicum SI
          Length = 324

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 46/148 (31%), Positives = 72/148 (48%), Gaps = 1/148 (0%)
 Frame = +1

Query: 94  NKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           N +I APM  I     R+LA ++G  +V TE + D   L    +   +L+          
Sbjct: 10  NPVIAAPMAGITDKAFRILAREFGCGLVCTEMVSDQALLHGNPKTCSLLDVAG------- 62

Query: 274 TIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAI-DINMGCPKEFSIKGGMGVA 450
                    E   V +Q+   + A   + A + E   A I DINMGCP    +K G G A
Sbjct: 63  ---------EAGPVSVQIFGSNAACMAEAAGIAESRGAGIIDINMGCPTPKIVKNGEGAA 113

Query: 451 LLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           L+ +P+KA +I++ +V+ + +PVT K+R
Sbjct: 114 LMREPEKAARIVRAVVERVKVPVTVKMR 141


>UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1;
           Desulfotalea psychrophila|Rep: TRNA-dihydrouridine
           synthase - Desulfotalea psychrophila
          Length = 328

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 49/157 (31%), Positives = 75/157 (47%), Gaps = 2/157 (1%)
 Frame = +1

Query: 70  FPINMN-YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNT 246
           F I  N + +  +LAP+     L  RLL  ++GAD   +E +       +++R  ++L +
Sbjct: 2   FTIGPNQFSSPFVLAPLAGYTDLSFRLLCHQFGADYTVSEMISCHGLFYNQQRTLEMLAS 61

Query: 247 VDYVDQTDGTIVFRTCEEEKKKVVLQL-GTCDEARALKVAKLVEHDVAAIDINMGCPKEF 423
           +                 E++ V  QL G   +  A     L +     IDINMGCP   
Sbjct: 62  LP----------------EERPVSFQLFGAEPDIMAKATLILNDFQPDMIDINMGCPVRK 105

Query: 424 SIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
             K G G AL+S P+ AY +++++VDN  IPVT K R
Sbjct: 106 VTKKGAGAALMSTPELAYDVIRSVVDNTDIPVTVKFR 142


>UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to MGC79829 protein - Nasonia vitripennis
          Length = 346

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 43/156 (27%), Positives = 77/156 (49%), Gaps = 2/156 (1%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           + APMVR   LP R L  KY  DI +T  ++   F++S +  +   +T    ++ D  ++
Sbjct: 17  VCAPMVRYSKLPFRTLVRKYDCDICFTPMILADSFVQSSKARDSEFST----NEGDSPLI 72

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
            +   +E    V            +  ++V      +D+N GCP+ +++K G G  LL+K
Sbjct: 73  VQFAAKEVDDFV------------EATEMVAPYSNGVDLNCGCPQRWALKDGYGADLLTK 120

Query: 463 PDKAYQILKTLVDNLSIP--VTCKIRILKTPEATLE 564
           P    +++  + + +  P  V+ KIRILK  + T+E
Sbjct: 121 PQLVKELVSNVRNRIPKPFTVSVKIRILKDIKKTIE 156


>UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3;
           Bacteroidales|Rep: Putative TIM-barrel enzyme -
           Bacteroides fragilis
          Length = 324

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 1/150 (0%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           E  + LAPM  +     RL+  K+GAD+VYTE +     +RS             V++T 
Sbjct: 10  ERPVFLAPMEDVTDPAFRLMCKKFGADMVYTEFVSSDALIRS-------------VNKTT 56

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAI-DINMGCPKEFSIKGGMGV 447
             +    C+EE+  V +Q+   D    +  A++VE     I DIN GCP +     G G 
Sbjct: 57  QKLTI--CDEERP-VAIQIYGKDTEAMVGAARIVEEAQPDILDINFGCPVKKVAGKGAGA 113

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
            +L    K  +I + +VD + IPVT K R+
Sbjct: 114 GMLQNIPKMLEITRAVVDAVKIPVTVKTRL 143


>UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4;
           Proteobacteria|Rep: Dihydrouridine synthase, DuS -
           Magnetospirillum gryphiswaldense
          Length = 335

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 46/150 (30%), Positives = 73/150 (48%), Gaps = 2/150 (1%)
 Frame = +1

Query: 94  NKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           N +ILAPM  +  +P R L  + GA +V +E +     +R+ R+   + +          
Sbjct: 18  NPVILAPMSGVTDMPCRRLVKRMGAGLVVSEMIASQAMIRANRQTMKMASN--------- 68

Query: 274 TIVFRTCEEEKKKVVLQLGTCDEARALKVAKL-VEHDVAAIDINMGCP-KEFSIKGGMGV 447
                 C EE    V QL  C+     + A++  +   A IDINMGCP K+ ++KG  G 
Sbjct: 69  ------CAEEHPMSV-QLAGCEPEVMAEAARMNADRGAAIIDINMGCPVKKVAVKGEAGS 121

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           AL+     A Q+++  V  + +PVT K R+
Sbjct: 122 ALMKDEILAGQLMEATVRAVDVPVTLKCRM 151


>UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 570

 Score = 62.9 bits (146), Expect = 8e-09
 Identities = 49/153 (32%), Positives = 75/153 (49%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +++ +K+ LAP+  IG LP R +  +YGADI   E  +    L+ +              
Sbjct: 214 IDFSDKLYLAPLTTIGNLPFRRICKQYGADITCGEMAMCTNLLQGQ-------------- 259

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLV--EHDVAAIDINMGCPKEFSIKG 435
           Q++  +V R   E+   V L  G   +    K A+L+  E DV  IDIN GCP +     
Sbjct: 260 QSEWALVKRHSSEDIFGVQL-CGAFPDTMT-KCAELLQKETDVDFIDINTGCPIDLVFNK 317

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G AL+ +  K  QI++ +   + IP+T KIR
Sbjct: 318 GAGSALMERKGKLQQIVQGMKSVIDIPLTVKIR 350


>UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1;
           Bdellovibrio bacteriovorus|Rep: Nitrogen regulation
           protein nifR3 - Bdellovibrio bacteriovorus
          Length = 352

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 32/82 (39%), Positives = 51/82 (62%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           LG  ++A A  V +LVE    AIDINMGCP + ++K   GVAL+  P  A ++++  V N
Sbjct: 82  LGNEEDAIAESVKRLVEWGAEAIDINMGCPVQKALKHNYGVALMGDPAYAAEVVRMTVKN 141

Query: 505 LSIPVTCKIRILKTPEATLELV 570
            ++PV+ K+R + + +   EL+
Sbjct: 142 STVPVSVKLRAVGSTKEFDELL 163


>UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=20;
           Euteleostomi|Rep: tRNA-dihydrouridine synthase 1-like -
           Homo sapiens (Human)
          Length = 473

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 44/159 (27%), Positives = 76/159 (47%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           ++APMV    L  RLL+ ++GA + YT  L    F+R            +Y  +    + 
Sbjct: 20  VVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRD----------ANYRKE---NLY 66

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
              C E+ + +++Q    D    ++ A L +    AID+N+GCP+  + +G  G  L  +
Sbjct: 67  CEVCPED-RPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDE 125

Query: 463 PDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
            D   +++    + LS+PVTCKIR+    + T+     L
Sbjct: 126 WDLLQRMILLAHEKLSVPVTCKIRVFPEIDKTVRYAQML 164


>UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10;
           Chlorobiaceae|Rep: TIM-barrel protein, nifR3 family -
           Chlorobium tepidum
          Length = 352

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 45/152 (29%), Positives = 71/152 (46%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++ +  IILAPM  +     R L  ++GADIVYTE      F+ ++     +  ++  + 
Sbjct: 11  IDIDRPIILAPMEDVTDRAFRQLCKQHGADIVYTE------FISAEALRRGVEKSIRKIT 64

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGM 441
             D          E+   V   G   E+     A    ++   +DIN GCP +     G 
Sbjct: 65  VAD---------HERPVAVQIFGNTVESMVEAAAIAETYEPDYLDINFGCPVKKVAGRGA 115

Query: 442 GVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           G ALL +P+K  +I   +V+ +S+PVT K RI
Sbjct: 116 GAALLKEPEKLSEIASAVVNAVSLPVTAKTRI 147


>UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine
           synthase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
           Strongly similar to tRNA-dihydrouridine synthase -
           Candidatus Kuenenia stuttgartiensis
          Length = 341

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 44/154 (28%), Positives = 68/154 (44%), Gaps = 1/154 (0%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           N+    ++ILAPM     +P RL+  ++G  + YTE                +++    V
Sbjct: 28  NIPVYGELILAPMAGFSDMPYRLICRRFGMSMSYTE----------------VVSVSGIV 71

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKG 435
                T      +EE++ V  Q+   DE +  +  K +E      IDINMGC        
Sbjct: 72  WNNKKTFKLLDFKEEERPVTFQVVGNDECQITEACKKIEQLGPDIIDINMGCSVSDIAGK 131

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           G G  +L  P K  ++   L  +LS+PVT KIR+
Sbjct: 132 GAGAGMLKHPSKISKMFNNLTGSLSVPVTGKIRL 165


>UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly
           dehydrogenase, nifR3 family protein; n=1; Planctomyces
           maris DSM 8797|Rep: Predicted TIM-barrel enzyme,
           possibly dehydrogenase, nifR3 family protein -
           Planctomyces maris DSM 8797
          Length = 365

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 34/105 (32%), Positives = 64/105 (60%), Gaps = 3/105 (2%)
 Frame = +1

Query: 232 DILNTVDYVDQTDGTI-VFRTCEEEKKKVVLQLGTCDEARALK-VAKLVE-HDVAAIDIN 402
           D++N    ++ ++ T+ + +TC E+    V   G+  E + +K  A+L+E   V +IDIN
Sbjct: 59  DLVNARGLLEGSEKTLQLTQTCPEDSPFAVQIFGS--EPQQMKDAAQLLESRGVHSIDIN 116

Query: 403 MGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           MGCP    +KGG G +++ +P     +++T+V+ + IPV+ K+R+
Sbjct: 117 MGCPVNRIVKGGAGASMMCRPSDTVSLVQTVVEAVKIPVSVKMRL 161


>UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protein;
           n=1; Trichomonas vaginalis G3|Rep: TIM-barrel protein,
           nifR3 family protein - Trichomonas vaginalis G3
          Length = 301

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 33/102 (32%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
 Frame = +1

Query: 232 DILNTVDYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLV-EHDVAAIDINMG 408
           ++++ +  V +   TI       ++KKV +Q+   D     + A+++ ++D + +DINMG
Sbjct: 24  EMVSAMALVYENKKTIDLLDISPKEKKVAVQIFGSDPDVMGEAARILNDYDFSYVDINMG 83

Query: 409 CPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           CP    +K   G  LLS P   Y I+K++V N + PVT K+R
Sbjct: 84  CPAPKIVKNNSGSHLLSNPSLVYDIVKSVVKNSNKPVTAKVR 125


>UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6;
           Saccharomycetales|Rep: Dihydrouridine synthase of tRNA -
           Pichia stipitis (Yeast)
          Length = 613

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 4/155 (2%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +++ N  I++P+  +G LP R L  K GADI Y+E  +    L++        N    + 
Sbjct: 240 LDFRNAKIVSPLTTVGNLPYRRLMKKLGADITYSEMALSVPLLQAT-------NAEWALP 292

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHD---VAAIDINMGCPKEFSIK 432
           +   T        E     +Q+ T     A KVA+++  +   V+ +++N GCP +   +
Sbjct: 293 KAHRT--------EYPGYGVQIATSKHWAAAKVAEIISRETEHVSELNLNCGCPIDLLYR 344

Query: 433 GGMGVALLSKPDKAYQILKTL-VDNLSIPVTCKIR 534
            G G ALL +P +  +ILK +   +  IPVT KIR
Sbjct: 345 QGQGSALLEQPARLVRILKAMNASSGDIPVTVKIR 379


>UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase;
           n=21; Alphaproteobacteria|Rep: Probable
           tRNA-dihydrouridine synthase - Rhodobacter capsulatus
           (Rhodopseudomonas capsulata)
          Length = 324

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 48/156 (30%), Positives = 81/156 (51%), Gaps = 3/156 (1%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           ++  +  ++LAPM  I  LP R +  ++GA +V +E +   + L +K        +V   
Sbjct: 7   SLRLDPPVLLAPMAGITDLPFRRMVARFGAGLVVSEMVASGEMLTAKP-------SVRAK 59

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIK 432
            Q + T    T         +QL   + A   + AK+V  D+ A  IDINMGCP +  + 
Sbjct: 60  AQAELTAGLPTS--------VQLAGREAAPMAEAAKIVA-DMGAEIIDINMGCPAK-KVT 109

Query: 433 GGM-GVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           GG+ G AL+  PD A ++++ +V  + +PVT K+R+
Sbjct: 110 GGLSGAALMRNPDHALRLIEAVVGAVDLPVTLKMRL 145


>UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein;
           n=2; Deltaproteobacteria|Rep: Dihydrouridine synthase
           family protein - Geobacter sulfurreducens
          Length = 325

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 49/147 (33%), Positives = 73/147 (49%)
 Frame = +1

Query: 94  NKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           N +ILAPM  I  LP RLLA + GA + +TE +     +R  ++  ++L +V   D+  G
Sbjct: 14  NNLILAPMAGITNLPFRLLAREQGAGLCFTEMVSVNGLVREGKKSFELLRSVPG-DRPLG 72

Query: 274 TIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVAL 453
                          +QL   D     +VA  V+     IDINMGCP +  +  G G AL
Sbjct: 73  ---------------IQLFGDDPDVMGRVAATVDGYGDLIDINMGCPVKKVVGTGAGSAL 117

Query: 454 LSKPDKAYQILKTLVDNLSIPVTCKIR 534
           + +PDK   I++ +     +P+T KIR
Sbjct: 118 MREPDKVRAIVRAVRRATRLPLTVKIR 144


>UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative;
           n=1; alpha proteobacterium HTCC2255|Rep:
           tRNA-dihydrouridine synthase, putative - alpha
           proteobacterium HTCC2255
          Length = 324

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 44/147 (29%), Positives = 73/147 (49%), Gaps = 1/147 (0%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           ++L+P+  I  LP R L   +GA +V +E +   + ++  +   D     +     +GT 
Sbjct: 11  VLLSPLAGITDLPYRNLVSSFGAGLVVSEMVASHEIMQKGK---DARARAELGFNVEGTS 67

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAI-DINMGCPKEFSIKGGMGVALL 456
           V             Q+   D     + AKL+E + A I DINMGCP +  + G  G AL+
Sbjct: 68  V-------------QIAGRDAFWMSECAKLIEGNGAKIIDINMGCPAKSVVNGASGSALM 114

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI 537
             PD A ++++ +V+ + IPVT K R+
Sbjct: 115 RTPDLALKLIEAVVNAVDIPVTLKTRL 141


>UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative;
           n=1; Filobasidiella neoformans|Rep: TRNA dihydrouridine
           synthase, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 610

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 33/102 (32%), Positives = 53/102 (51%)
 Frame = +1

Query: 256 VDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKG 435
           +D+  G       E   + +++Q    D    L  AK VEH   A+DIN GCP+  + +G
Sbjct: 133 LDEEGGEGTIGGVEGGDRPLIVQFCANDPDILLAAAKKVEHRCDAVDINFGCPQGIAKRG 192

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATL 561
             G  L  + +  ++++ TL +NLS+PVT K RI    + T+
Sbjct: 193 HYGSFLQDEWELIHKLISTLHENLSVPVTAKFRIFPDLDKTI 234


>UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 4 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 367

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 46/162 (28%), Positives = 77/162 (47%), Gaps = 3/162 (1%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKR-RFNDILNTVDYVDQTDGTI 279
           I  PMVR   LP R L  +Y  DIVY+  ++  +++R++  R +D+              
Sbjct: 42  IAGPMVRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDL-------------- 87

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLS 459
              +   E   +++Q+G  + A  LK  ++V      I IN GCP +  I+ G+G AL+ 
Sbjct: 88  ---STNNEDTPLIVQVGVNNVADLLKFVEMVAPYCDGIGINCGCPIKEQIREGIGCALIY 144

Query: 460 KPDKAYQILKTLVDNL--SIPVTCKIRILKTPEATLELVNKL 579
             D    ++  + D     + +  KIRI +  + T+EL  KL
Sbjct: 145 NSDLLCSMVHAVKDKYGDKLRIETKIRIHEALDETVELCRKL 186


>UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2;
           Culicidae|Rep: tRNA-dihydrouridine synthase - Aedes
           aegypti (Yellowfever mosquito)
          Length = 391

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 46/163 (28%), Positives = 76/163 (46%), Gaps = 4/163 (2%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRS-KRRFNDILNTVDYVDQTDGTI 279
           I APMVR   L  R L   YG D+ +T  ++   F +S K R N+               
Sbjct: 26  ICAPMVRYSKLEFRNLVRSYGTDLTFTSMIMADSFCQSEKARLNEF-------------- 71

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLS 459
              T   +   V+ Q    +    L   ++    V  +D+N GCP+ ++++ G G ALL 
Sbjct: 72  ---TTNRDDTPVIAQFAAKNAVDFLSATEMTFPYVDGVDLNCGCPQRWAMQDGYGSALLR 128

Query: 460 KPDKAYQILKTLVDNL--SIPVTCKIRIL-KTPEATLELVNKL 579
            P+    +L T+  NL  +  V+ K+R+L K+  AT+++  +L
Sbjct: 129 TPELIADMLSTVRRNLPSTFSVSVKVRLLQKSLSATIDMCRQL 171


>UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Putative TIM-barrel protein, nifR3 family - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 320

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 44/149 (29%), Positives = 68/149 (45%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           + ++  LAPM  +    +RL   K GA +V TE       +  + +  + + T+      
Sbjct: 5   FSSRAFLAPMAGVSDPALRLQCKKMGAGLVVTEFTSIHSIIAKEEQLKENMKTIQE---- 60

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
                F    E+++ + +QL   D     K A +VE     ID NMGCP     +   G 
Sbjct: 61  -----FIEFSEQERPISVQLFGSDLYALEKAATIVEPYFDIIDYNMGCPAPHITQQMAGG 115

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           ALL + +   QI +TLV+ +  PVT KIR
Sbjct: 116 ALLQEVNLTQQIFETLVNAVKKPVTLKIR 144


>UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=28;
           Eumetazoa|Rep: tRNA-dihydrouridine synthase 4-like -
           Homo sapiens (Human)
          Length = 317

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 48/173 (27%), Positives = 81/173 (46%), Gaps = 5/173 (2%)
 Frame = +1

Query: 73  PINMNYENKII--LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNT 246
           PI M +  +++   APMVR   L  R L  KY  D+ YT  ++   F++S +  +    T
Sbjct: 18  PIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTT 77

Query: 247 VDYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFS 426
               +Q D       C      +++Q    D       A++V      IDIN GCP+ ++
Sbjct: 78  ----NQGD-------CP-----LIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWA 121

Query: 427 IKGGMGVALLSKPDKAYQILKTLVDNLSIP---VTCKIRILKTPEATLELVNK 576
           +  G G  L++KP+    ++K + + +  P   V+ KIRI    + T++L  K
Sbjct: 122 MAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQK 174


>UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3;
           Mollicutes|Rep: TRNA dihydrouridine synthetase -
           Mesoplasma florum (Acholeplasma florum)
          Length = 325

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 46/171 (26%), Positives = 88/171 (51%), Gaps = 3/171 (1%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEEL-IDWKFLRSKRRFNDILNTVDY 255
           N+  + K++  PM  +   P RL++ + GAD+V  E + ++     +K+ F+ +      
Sbjct: 5   NVEIKGKLVQGPMAGVSNPPFRLISKEKGADLVCAEMVSVEGMTHNNKKTFSMLA----- 59

Query: 256 VDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPK-EFSIK 432
           V++ +  +  +    + +  ++     DE         V+ D+  ID+N+GCP  + +++
Sbjct: 60  VEKKEHPMSMQIFGNDVESFIVATKWIDEN--------VDCDI--IDLNIGCPAPKVAVR 109

Query: 433 GGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLEL-VNKLI 582
              G +LL  P+  Y I+K +V+N S PVT KIR+    E+   + V+KLI
Sbjct: 110 SASGSSLLKTPELIYDIVKAVVENTSKPVTAKIRLGWDKESVNAVEVSKLI 160


>UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Psychroflexus torquis ATCC 700755|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Psychroflexus torquis ATCC 700755
          Length = 338

 Score = 59.7 bits (138), Expect = 7e-08
 Identities = 49/175 (28%), Positives = 78/175 (44%), Gaps = 3/175 (1%)
 Frame = +1

Query: 64  LQFPINMNYEN-KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDIL 240
           + FP+ ++ +   I LAPM  +  L  RLLA + GAD   TE        R  +  N  L
Sbjct: 1   MAFPVGVSLDPVPIFLAPMAGVTDLAYRLLAKECGADFTVTEFTAASGLTR--KNTNSWL 58

Query: 241 NTVDYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKE 420
                  +TD           +K  + Q+   D +   K   ++E     IDIN GCP  
Sbjct: 59  KV-----ETD---------PREKPFIPQIFGGDISEMAKTVGMLEDRSDVIDINFGCPAP 104

Query: 421 FSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI--LKTPEATLELVNKL 579
              +   G ALL  PDK   +++  +++ ++P+T K+R+     P   LE+  +L
Sbjct: 105 KVCRNDAGAALLRDPDKVVSMVRRCIESTNVPITVKMRLGTGSGPNTALEISKRL 159


>UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putative;
           n=1; Trypanosoma brucei|Rep: TRNA-dihydrouridine
           synthase 1, putative - Trypanosoma brucei
          Length = 520

 Score = 59.7 bits (138), Expect = 7e-08
 Identities = 45/169 (26%), Positives = 69/169 (40%), Gaps = 10/169 (5%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD----QTD 270
           ++ PMV    LP RLL  +YGA + YT       F +S        +T  +      ++ 
Sbjct: 76  VVGPMVDQSELPFRLLCRRYGATLAYTPMFHAKSFAQSAHYRQRYFSTTTFPPHSAMESG 135

Query: 271 GTIVFRTCE------EEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIK 432
           G +            +    +  Q    D    L  A+ VE    A+D N+GCP+  + +
Sbjct: 136 GNVAANDSTSNDGALDNDHPLFAQFCGNDPETVLAAARHVEDYCEAVDFNIGCPQGIARR 195

Query: 433 GGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
           G  G  L+   +  + IL  L   L +PVT K+RI      TL+    L
Sbjct: 196 GHYGSFLMEDWELLHNILHALAVELRVPVTAKMRIFDDEALTLKYAEML 244


>UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15;
           Pezizomycotina|Rep: Uncharacterized conserved protein -
           Aspergillus oryzae
          Length = 730

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 49/178 (27%), Positives = 87/178 (48%), Gaps = 12/178 (6%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDIL--NTVDYVDQT--D 270
           +LAP+   G LP R L ++ GA   Y+E  +    ++ +R    ++  +  + +  T   
Sbjct: 322 VLAPLTTQGNLPFRRLCIELGAQFTYSEMALSMPLIQGQRGEWALMRAHETEMLPPTISP 381

Query: 271 GTIVFRTCEEEKK-KVVLQLGTCDEARALKVAKLVE---HDVAAIDINMGCPKEFSIKGG 438
           G  V +  +  K  +   Q+      +ALK  +++     ++  ID+N GCP +   + G
Sbjct: 382 GADVVQGYDHSKDFRFGAQIAANKHWQALKATEVLSAYTPNLRVIDLNCGCPIDLLFREG 441

Query: 439 MGVALLSKPDKAYQILKTL-VDNLSIPVTCKIRI---LKTPEATLELVNKLITYQFQS 600
            G ALL  P K  +IL+ +   +  IP+T KIR+     +P A L+L  +LI   ++S
Sbjct: 442 AGSALLEHPSKLERILRGMNAVSQEIPITAKIRMGTRDNSPNA-LKLAERLILGGYES 498


>UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 527

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 43/160 (26%), Positives = 73/160 (45%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           +LAPMV    L  R+   KYGA + +T  +    F+       + L  V    + D  +V
Sbjct: 76  VLAPMVDQSELAFRMFTRKYGAQLTFTPMIHAHLFVNDGTYRRNSLALV----KADRPLV 131

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
            + C     KV   L  C         +LVE     +D+N+GCP+  + +G  G  L  +
Sbjct: 132 VQFC---ANKVDTFLAAC---------RLVEDVCDGVDLNLGCPQMVAKRGRYGSWLQDE 179

Query: 463 PDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
            D   +++  + D   +P++CKIR+    + T+E   +L+
Sbjct: 180 VDLICEMVSAVRDYCRLPISCKIRVRDDRQQTVEYAKRLV 219


>UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1;
           Parabacteroides distasonis ATCC 8503|Rep: Putative
           TIM-barrel enzyme - Parabacteroides distasonis (strain
           ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 329

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 43/150 (28%), Positives = 70/150 (46%), Gaps = 1/150 (0%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           E  + LAPM  +  +  RL+  ++GAD+VYTE +     +RS  +    LN  D      
Sbjct: 10  ERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSSDALIRSVNKTQQKLNVSD------ 63

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAI-DINMGCPKEFSIKGGMGV 447
                     +++ V +Q+   D A  ++ A++ E     I DIN GCP +     G G 
Sbjct: 64  ----------DERPVAIQIYGKDVASMVEAARICEEARPDILDINFGCPVKKVAGKGAGA 113

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
            +L       +I + +V  ++IPVT K R+
Sbjct: 114 GMLRNIPLMLEITREVVKAVNIPVTVKTRL 143


>UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2;
           Desulfitobacterium hafniense|Rep: Putative
           uncharacterized protein - Desulfitobacterium hafniense
           (strain Y51)
          Length = 326

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 33/85 (38%), Positives = 44/85 (51%)
 Frame = +1

Query: 298 EEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAY 477
           E   ++V   G+  E  A   A  VE D   IDINMGCP    +K G G ALL     A 
Sbjct: 68  EASPRIVQLFGSEPEVMAKAAALAVERDAEIIDINMGCPTPKIVKNGEGSALLQDLPLAQ 127

Query: 478 QILKTLVDNLSIPVTCKIRILKTPE 552
           +I + +V  + +PVT K+R+  T E
Sbjct: 128 RIAEAVVKAVEVPVTVKMRLGWTAE 152


>UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein
           Y37E11B.5; n=2; Caenorhabditis|Rep: Putative
           uncharacterized protein Y37E11B.5 - Caenorhabditis
           elegans
          Length = 554

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 9/169 (5%)
 Frame = +1

Query: 73  PINM-NYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTV 249
           P+NM + + K  LAP+  +G LP R + + YGADI   E  +    L        +L   
Sbjct: 196 PLNMGSLDGKKYLAPLTTVGNLPFRRICVDYGADITCGEMALATSILSGTASEYSLLKR- 254

Query: 250 DYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSI 429
                         CE+    V L  G  D         +   DV  IDINMGCP +   
Sbjct: 255 ------------HPCEKIFG-VQLAGGFADTMAKASQIVVENFDVDFIDINMGCPIDVVN 301

Query: 430 KGGMGVALLSKPDKAYQILKTLVDNLS--IPVTCKIR------ILKTPE 552
           + G G AL S+P K +++L      L    P+T KIR      +LK PE
Sbjct: 302 QKGGGCALPSRPQKLFEVLAATKSVLGGCCPLTVKIRTGMKEGVLKAPE 350


>UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2;
           Theileria|Rep: Putative uncharacterized protein -
           Theileria annulata
          Length = 359

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 39/123 (31%), Positives = 59/123 (47%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           K I+APMV    LP RLL  +Y AD+ YT  ++  K       + +I             
Sbjct: 27  KFIVAPMVDQSELPFRLLCRRYSADLAYTP-MLHAKIFSENENYRNIH------------ 73

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
             F T  ++K  +    G  D +  +  +  +++DV+AIDIN+GCP+  + KG  G  LL
Sbjct: 74  --FHTSSDDKPLIAQFCGN-DPSAFILASSYIKNDVSAIDINLGCPQGIAKKGRYGSFLL 130

Query: 457 SKP 465
             P
Sbjct: 131 EYP 133


>UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG07217.1 - Gibberella zeae PH-1
          Length = 510

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 31/92 (33%), Positives = 46/92 (50%)
 Frame = +1

Query: 307 KKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQIL 486
           + + +Q    D    L  AK V     A+D+N+GCP+  + KG  G  L    D  ++++
Sbjct: 102 RPLFVQFCANDPDALLSAAKQVAPYCDAVDLNLGCPQGIARKGKYGAFLQEDQDLIFRLI 161

Query: 487 KTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
             L   L +PVT KIRIL T E TL     ++
Sbjct: 162 NILHKELPVPVTAKIRILDTKEETLAYAQNVL 193


>UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 660

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 43/153 (28%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +++ +K+ LAP+   G LP R +  ++GADI   E  +    L+ +              
Sbjct: 311 VDFRDKLYLAPLTTCGNLPFRRVCKRFGADITCGEMAMCTNLLQGQA------------- 357

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH--DVAAIDINMGCPKEFSIKG 435
            ++  ++ R   E+   V  QL  C      + A+L+    DV  +DIN GCP +   K 
Sbjct: 358 -SEWALLKRHASEDLFGV--QLEGCFPDTMTRCAELLNQNIDVDFVDINSGCPIDLVYKK 414

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G  L+++  K  QI++ +   L +P+T KIR
Sbjct: 415 GGGCGLMTRTSKFEQIVRGMNSVLDVPLTVKIR 447


>UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative;
           n=10; Rhodobacterales|Rep: TRNA-dihydrouridine synthase,
           putative - Silicibacter pomeroyi
          Length = 327

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 43/147 (29%), Positives = 69/147 (46%), Gaps = 1/147 (0%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           +ILAPM  I   P R L +++GA +V +E +   + +++K    +       V+ T    
Sbjct: 14  VILAPMAGITDRPFRDLVMEFGAGMVVSEMVASQEMVQAKPGVRERAELSADVENT---- 69

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLV-EHDVAAIDINMGCPKEFSIKGGMGVALL 456
                        +QL   D     + A+ V +     IDINMGCP +    G  G ALL
Sbjct: 70  ------------AVQLAGRDTHWIAEAARQVADRGARVIDINMGCPAKKVTNGYSGSALL 117

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI 537
             PD A ++++ +V  + +PVT K R+
Sbjct: 118 KTPDHALRLIEAVVAAVDVPVTLKTRL 144


>UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein,
           putative; n=9; Pezizomycotina|Rep: Dihydrouridine
           synthase family protein, putative - Aspergillus
           fumigatus (Sartorya fumigata)
          Length = 541

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 32/110 (29%), Positives = 55/110 (50%)
 Frame = +1

Query: 256 VDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKG 435
           +D+ D ++         + +++Q    D    L+ A+ V     A+D+N+GCP+  + KG
Sbjct: 108 LDKNDNSLYLDGNPAFDRPLIVQFCANDPDDFLEAARHVAPYCDAVDLNLGCPQGIARKG 167

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLIT 585
             G  L    D  Y+++  L   L IPVT K RI ++ E TLE    +++
Sbjct: 168 HYGAFLQEDWDLIYKLINRLHKELPIPVTAKFRIQESKEKTLEYAKMILS 217


>UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Syntrophobacter fumaroxidans MPOB|Rep: Putative
           TIM-barrel protein, nifR3 family - Syntrophobacter
           fumaroxidans (strain DSM 10017 / MPOB)
          Length = 352

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 46/147 (31%), Positives = 71/147 (48%), Gaps = 1/147 (0%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           ++LAPM  +     R L   +GA +V TE +     +R++R       T+D   Q     
Sbjct: 24  LVLAPMAGVTDSAYRALMADFGAAMVTTEMVSIQGLVRNQRA------TLDLCRQQHPVG 77

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA-IDINMGCPKEFSIKGGMGVALL 456
           V          + +Q+   D A   + A+LVE   AA IDIN GCP    ++ G G  LL
Sbjct: 78  V---------PLAVQVFGRDPAVMAEAARLVEQGGAALIDINAGCPVRKVVRQGAGAILL 128

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI 537
             PD+   +++ +   +S+PVT KIR+
Sbjct: 129 KDPDRLAAMVEAVKRAVSVPVTVKIRV 155


>UniRef50_A4S3Q5 Cluster: Predicted protein; n=2; Eukaryota|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 361

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 41/154 (26%), Positives = 75/154 (48%), Gaps = 2/154 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++++ K+ +AP+  +G LP R +    GADI  +E  +    L+  R+   +L       
Sbjct: 4   LDFKGKLYVAPLTTVGNLPFRRVCTDLGADITVSEMAMASNLLKGDRKEWALL------- 56

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIKG 435
                   R    EK   +   G   +  A + A+L++++V+   ID+NMGCP +     
Sbjct: 57  --------RRHPSEKCYGIQVCGGYPDLMA-RCAELIDNEVSCDFIDVNMGCPIDGVCAK 107

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           G G +L+   D+   +++T+    S PVT K+R+
Sbjct: 108 GAGSSLMRDTDRLKNVVRTMAAVSSTPVTIKLRM 141


>UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 364

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 40/158 (25%), Positives = 76/158 (48%), Gaps = 5/158 (3%)
 Frame = +1

Query: 109 APMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDY-VDQTDGTIVF 285
           APMV    L  RL  ++ GA + +T+  +  +    +     +L +++   + T     +
Sbjct: 17  APMVGQSDLAFRLQTVQNGATLTWTQMYLAPELSSDQYMLESLLKSLEMGSNATKNMARY 76

Query: 286 RTC--EEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLS 459
           R     ++    V+QL   +  + ++ A+ V     AID+N+GCP+  + +G  G  LL 
Sbjct: 77  RASPLHDQSAPQVVQLAGNNVQQLVEAARRVAPYADAIDLNLGCPQRHAEQGHYGACLLP 136

Query: 460 KPD--KAYQILKTLVDNLSIPVTCKIRILKTPEATLEL 567
           K +     +I+  +V  + +P+T KIR+    E T +L
Sbjct: 137 KQNWPLVAEIVSGMVQAVDVPITTKIRLPVPKEQTAQL 174


>UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protein
           NifR3; n=3; Acetobacteraceae|Rep: Nitrogen assimilation
           regulatory protein NifR3 - Gluconobacter oxydans
           (Gluconobacter suboxydans)
          Length = 371

 Score = 56.0 bits (129), Expect = 9e-07
 Identities = 45/151 (29%), Positives = 70/151 (46%), Gaps = 2/151 (1%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           E+ +ILAP+  +  LP R LA   GA +V +E +  W  +R         NT+       
Sbjct: 34  EDPVILAPLSGVTDLPFRQLARDLGAGLVVSEMIASWAMIRENE------NTMRMARMA- 86

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKL-VEHDVAAIDINMGCP-KEFSIKGGMG 444
                     E+    +QL  CD     + AK+ V+     IDIN GCP K+ +I    G
Sbjct: 87  ----------ERGPNAVQLAGCDPKAMAQAAKISVDGGANLIDINFGCPVKKVAIGQMAG 136

Query: 445 VALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
            AL+     A ++L+     +++PVT K+R+
Sbjct: 137 SALMRDEVLAGKLLEATARAVNVPVTLKMRM 167


>UniRef50_A6VYA3 Cluster: TIM-barrel protein, yjbN family; n=8;
           Proteobacteria|Rep: TIM-barrel protein, yjbN family -
           Marinomonas sp. MWYL1
          Length = 341

 Score = 56.0 bits (129), Expect = 9e-07
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
 Frame = +1

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALLS 459
           F   +E +  + LQLG  D     K AK+ E      +++N+GCP +      +G  L++
Sbjct: 65  FLRYDECEHPIALQLGGSDAVALGKCAKMAEQAGFDEVNLNVGCPSDRVQNSLIGACLMA 124

Query: 460 KPDKAYQILKTLVDNLSIPVTCKIRI 537
            PDK  + ++ + DN SIPVT K RI
Sbjct: 125 HPDKVKEAMRAMQDNCSIPVTIKHRI 150


>UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase;
           n=39; Proteobacteria|Rep: Probable tRNA-dihydrouridine
           synthase - Rickettsia prowazekii
          Length = 327

 Score = 56.0 bits (129), Expect = 9e-07
 Identities = 43/153 (28%), Positives = 70/153 (45%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           N+   + +ILAPM  +  L  R L  ++GA +V   E+I  + +  K R +     + + 
Sbjct: 6   NIELSSNVILAPMSDVTDLEFRKLVKRFGAGLV-VSEMIASRAMIMKSRQSMQKCAIMHD 64

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGG 438
           D T   +    CE +   V+ +    +E    K+          ID+N GCP +  + G 
Sbjct: 65  DPTSACVQLAGCEPD---VIAEAAKMNEDMGAKI----------IDLNFGCPAKKVVGGY 111

Query: 439 MGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
            G AL+     A +I +  V  + IPVT K+RI
Sbjct: 112 AGSALMRDEQLAAKIFEATVKAVKIPVTVKMRI 144


>UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 family;
           n=2; Clostridiales|Rep: Putative TIM-barrel protein,
           NifR3 family - Syntrophomonas wolfei subsp. wolfei
           (strain Goettingen)
          Length = 318

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 1/149 (0%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           EN++  APM  +     R+LA  +G  +V +E + D   +  + R + I ++        
Sbjct: 10  ENRVCAAPMAGVSDKAYRVLARDFGCGLVCSEMVSDKGLVYGQGRTSKIADS-------- 61

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVA-AIDINMGCPKEFSIKGGMGV 447
                     EK+ V +Q+   +       A++VE   A  IDINMGCP    +K G G 
Sbjct: 62  --------SGEKRPVAVQIFGSEAESMATAARIVEEMGADIIDINMGCPTPKIVKNGEGA 113

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           AL+    K+  I++ ++  + +PVT K+R
Sbjct: 114 ALMLDITKSRGIVREVLRVVKVPVTVKMR 142


>UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1;
           Petrotoga mobilis SJ95|Rep: Dihydrouridine synthase, DuS
           - Petrotoga mobilis SJ95
          Length = 301

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 39/149 (26%), Positives = 67/149 (44%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           EN+I LAPM      P R +  ++GA   +TE +     +R   +   +L          
Sbjct: 3   ENQIGLAPMADYTDYPFREICRRFGAKFTFTEMISVDSIIRENEKVEKMLP--------- 53

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVA 450
                   ++ +  + +QL   +  + ++ AK ++H  + IDIN  CP    +K G G A
Sbjct: 54  --------QKGEDNIGVQLFGNETTKFIEAAKSIQHLASWIDINAACPVNKVVKKGSGAA 105

Query: 451 LLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           LL  P     I+  L  ++ +PV  K+R+
Sbjct: 106 LLKNPKLLGDIVFNLKKSIDLPVGVKVRL 134


>UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231;
           Bacteria|Rep: tRNA-dihydrouridine synthase A - Shigella
           flexneri
          Length = 330

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 43/125 (34%), Positives = 60/125 (48%), Gaps = 9/125 (7%)
 Frame = +1

Query: 190 LIDWKFLRSKRRFNDIL--NTVDYVDQ-TDGTIV-----FRTCEEEKKKVVLQLGTCDEA 345
           ++DW   R  R F  +L  NT+ Y +  T G I+     +    EE+  V LQLG  D A
Sbjct: 18  MLDWTD-RHCRYFLRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPA 76

Query: 346 RALKVAKLVE-HDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVT 522
              + AKL E      I++N+GCP +    G  G  L+         +K + D +SIPVT
Sbjct: 77  ALAQCAKLAEARGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVT 136

Query: 523 CKIRI 537
            K RI
Sbjct: 137 VKTRI 141


>UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Novel
           protein - Mus musculus (Mouse)
          Length = 194

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 45/159 (28%), Positives = 72/159 (45%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           ++APMV    L  RLL+ ++GA + YT  L    F+R      + L    Y D       
Sbjct: 20  VVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENL----YCD------- 68

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
              C E++  +V            + A L +    AID+N+GCP+  + +G  G  L  +
Sbjct: 69  --VCPEDRPLIV------------QAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEE 114

Query: 463 PDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
            D   +++    + LS+PVTCKIR+    + T+     L
Sbjct: 115 WDLLQRMILLAHERLSVPVTCKIRVFPEIDKTVRYAQML 153


>UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Putative
           uncharacterized protein - Lentisphaera araneosa HTCC2155
          Length = 330

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           +G   E  A     +V+    A+D+NMGCP + ++KGG+G A+L  P   YQ+L ++ + 
Sbjct: 69  MGNNAELMAESAKLVVDCGADAVDVNMGCPTKRAVKGGVGSAMLKDPKLCYQVLASMREQ 128

Query: 505 LSIPVTCKIRI-LKTPEATLELVNKLI 582
           +   ++ KIR      E   E++  ++
Sbjct: 129 VPCALSAKIRAGFDNKEGVFEILQAIV 155


>UniRef50_UPI0000DAE45A Cluster: hypothetical protein
           Rgryl_01000346; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000346 - Rickettsiella
           grylli
          Length = 330

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 29/84 (34%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
 Frame = +1

Query: 289 TCEEEKKKVVLQLGTCDEARALKVAKLVE-HDVAAIDINMGCPKEFSIKGGMGVALLSKP 465
           T +  +K + +QLG    +   K AK+VE +  + I++N+GCP E    GG GV LL +P
Sbjct: 59  TVDANEKALAIQLGGGIASDLSKAAKIVESYGYSEINLNVGCPSEKVQSGGFGVVLLKEP 118

Query: 466 DKAYQILKTLVDNLSIPVTCKIRI 537
           ++    +  +   + +PVT K RI
Sbjct: 119 NRVADAIAAMKAVVRLPVTVKTRI 142


>UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=20;
           Streptococcus|Rep: Possible transcriptional regulator -
           Streptococcus thermophilus (strain ATCC BAA-250 / LMG
           18311)
          Length = 350

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 40/154 (25%), Positives = 69/154 (44%), Gaps = 2/154 (1%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           N+   ++ +LAPM  +     R +A ++ A +V  E + +   L +  +   +L+     
Sbjct: 37  NVEIPHRTVLAPMAGVTNSAFRTIAKEFSAGLVVMEMISEKGLLYNNEKTLHMLHI---- 92

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIK 432
                       +E +  + +QL   D     + A  ++ +  A  +DINMGCP    +K
Sbjct: 93  ------------DENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIVDINMGCPVNKVVK 140

Query: 433 GGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
              G   L  PDK Y I+K +   L IP+T K+R
Sbjct: 141 NEAGAKWLKDPDKIYHIVKEVTSVLDIPLTVKMR 174


>UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR -
           Leptospira interrogans
          Length = 329

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 47/157 (29%), Positives = 78/157 (49%), Gaps = 4/157 (2%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           N+    KI L+PM  I   P R +  K+GA   YTE                 +NT + V
Sbjct: 6   NVTIPGKISLSPMAGISDSPTRRICRKFGAAFSYTE----------------FVNTDELV 49

Query: 259 DQTDGTIVFRTCEEEKKKVVLQL-GTCDE--ARALKVAKLVEHDVAAIDINMGCP-KEFS 426
            +    +     + E++ +  Q+ G   E  A A ++ + ++ D+  ID+NMGC  ++ S
Sbjct: 50  HRAPKALKMFRYKLEERPITFQIFGNRLEIIAEAAEIIQELKPDI--IDLNMGCSTRKVS 107

Query: 427 IKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           ++G  G  LL +P  A +I++ +   ++IPVT KIRI
Sbjct: 108 LRGA-GAGLLRRPLLAGKIIEAIKKRVNIPVTAKIRI 143


>UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly
           dehydrogenase, nifR3 family protein; n=1; Planctomyces
           maris DSM 8797|Rep: Predicted TIM-barrel enzyme,
           possibly dehydrogenase, nifR3 family protein -
           Planctomyces maris DSM 8797
          Length = 355

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 25/57 (43%), Positives = 36/57 (63%)
 Frame = +1

Query: 367 LVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           L +H  AA+D+NMGCP       G G  ++  PD A Q++  +VD +SIPVT K+R+
Sbjct: 100 LEQHGYAAVDLNMGCPMAKINGNGGGARIMCAPDAACQLVAEVVDAVSIPVTVKMRL 156


>UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 307

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 40/153 (26%), Positives = 69/153 (45%)
 Frame = +1

Query: 106 LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVF 285
           +APMV    L  R L  +YGA + YT  +    F+ S +   +I +T       D  ++ 
Sbjct: 20  VAPMVDQSELAFRELCKRYGATLGYTPMIHARLFVESPKYRREIFST----STRDRPLLA 75

Query: 286 RTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKP 465
           + C  + + +            L+ A ++      +DIN GCP+  + +G  G  L+   
Sbjct: 76  QFCANDPEIL------------LRAATMIAPYCDGVDINFGCPQRIAKRGNYGAFLMDDW 123

Query: 466 DKAYQILKTLVDNLSIPVTCKIRILKTPEATLE 564
                +++ L + L +PVT KIR+    E TL+
Sbjct: 124 KTVEALIRKLDEELPVPVTAKIRVYDDLETTLK 156


>UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultured
           bacterium 578|Rep: NifR3/Smm1 family protein -
           uncultured bacterium 578
          Length = 322

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 42/148 (28%), Positives = 72/148 (48%), Gaps = 1/148 (0%)
 Frame = +1

Query: 94  NKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           +K++LAPM      P R++  + GA +  +E ++  K L         LNT    +++  
Sbjct: 10  SKVLLAPMAGTSDKPFRMICREQGAALTTSEMVVMQKHL---------LNT----NKSKH 56

Query: 274 TIVFRTCEEEKKKVVLQLGTCDEARALKVAK-LVEHDVAAIDINMGCPKEFSIKGGMGVA 450
            + FR+   E+  + +Q+   +     + AK  +E     IDINMGCP +       G A
Sbjct: 57  RLDFRS---EQSPISIQIAGSESQELAESAKQALEFGADIIDINMGCPAKKVCNKAAGSA 113

Query: 451 LLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           L+        I+K +V+ ++IPVT K+R
Sbjct: 114 LMKNEKLVEDIIKAVVNAVNIPVTLKMR 141


>UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter
           ruber DSM 13855|Rep: NifR3 family enzyme - Salinibacter
           ruber (strain DSM 13855)
          Length = 443

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 44/150 (29%), Positives = 65/150 (43%), Gaps = 1/150 (0%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           +  + LAPM  +   P R+L  +YGAD++YTE +     LR +   +  L   D      
Sbjct: 74  DRPLFLAPMEDVSDPPFRILCKRYGADMMYTEFVSSAGLLREQEHEHQKLEIFD------ 127

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEAR-ALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
                   EE    + +  G  DE R A  +      DV  IDIN GCP    ++   G 
Sbjct: 128 --------EERPIGIQVWGGGIDEVRNATPMVDAAGPDV--IDINFGCPVRKIVQKDGGA 177

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
            +L   DK   I   +++  + PVT K R+
Sbjct: 178 GVLRNLDKMRNITAAVMEEATRPVTVKTRL 207


>UniRef50_Q010A0 Cluster: tRNA-dihydrouridine synthase; n=1;
           Ostreococcus tauri|Rep: tRNA-dihydrouridine synthase -
           Ostreococcus tauri
          Length = 639

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 40/156 (25%), Positives = 77/156 (49%), Gaps = 2/156 (1%)
 Frame = +1

Query: 76  INMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDY 255
           +++ ++ KI +AP+  +G LP R +    GADI  +E  +    L+  R+          
Sbjct: 263 VSLEFKGKIYVAPLTTVGNLPFRRICTDLGADITVSEMAMASNLLKGDRK---------- 312

Query: 256 VDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSI 429
               +  +V R   E+   + +  G  D     + A+L++++V    ID+NMGCP +   
Sbjct: 313 ----EWALVRRHPIEKCFGIQICGGYPD--LMTRCAELLDNEVHCDFIDVNMGCPIDGVC 366

Query: 430 KGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
             G G +L+   D+  ++++++    S PVT K+R+
Sbjct: 367 AKGAGGSLMRDTDRLKRVVRSMTSVSSTPVTIKLRM 402


>UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6;
           Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase B
           - Serratia marcescens
          Length = 334

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 48/154 (31%), Positives = 68/154 (44%), Gaps = 1/154 (0%)
 Frame = +1

Query: 94  NKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           N +I APM  I   P R L    GA +  +E                +L++   V +TD 
Sbjct: 10  NCLIAAPMAGITDRPFRTLCHAMGAGMAVSE----------------MLSSNPEVWRTDK 53

Query: 274 TIVFRTCEEEKKKVVLQLGTCDEARALKVAKL-VEHDVAAIDINMGCPKEFSIKGGMGVA 450
           + +     +E     +Q+  CD       A++ V      IDINMGCP +   +   G A
Sbjct: 54  SRLRMVHSDEPGIRSVQIAGCDPDDMAAAARINVASGAQLIDINMGCPAKKVNRKLAGSA 113

Query: 451 LLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPE 552
           LL  PD   +IL  +VD + +PVT KIR    PE
Sbjct: 114 LLQYPDLVKRILHAVVDAVDVPVTLKIRTGWAPE 147


>UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Rhodospirillum rubrum ATCC 11170|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 362

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 47/147 (31%), Positives = 68/147 (46%), Gaps = 1/147 (0%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           I+LAPM  +   P R LA  YG  + +TE +   + LR + R  D            G  
Sbjct: 14  IMLAPMAGVTDSPFRRLAHDYGCPLSWTEMVASRELLRERARGVD-------PRLGGGAE 66

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA-IDINMGCPKEFSIKGGMGVALL 456
             R          +QL  CD     + A+ VE   A  IDINMGCP    + G  G AL+
Sbjct: 67  AGRA-----GPFAVQLAGCDPLIMAEAARRVEGAGAELIDINMGCPVRKVVGGLGGSALM 121

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI 537
                A +IL+ +V  +++PV+ K+R+
Sbjct: 122 RDLPLAARILEAVVGAVTLPVSLKMRL 148


>UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putative;
           n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 3,
           putative - Trypanosoma brucei
          Length = 528

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 46/172 (26%), Positives = 82/172 (47%), Gaps = 4/172 (2%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           + NK++LAP+  +G LP R +  +YGADI   E                I++ ++ + ++
Sbjct: 164 FSNKLVLAPLTTVGNLPFRRVCKEYGADITVGEMA--------------IVHNLNRLQKS 209

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA---IDINMGCPKEFSIKGG 438
           + +++ R   E+     LQ+       A+  A+ VE    +   +DIN GCP +  +  G
Sbjct: 210 EWSLLRRHSSED--IFGLQIAVSRPHDAITWAQAVEESGFSYDFVDINCGCPVDKVVLSG 267

Query: 439 MGVALLS-KPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLITYQ 591
            G  L   K ++   ++++LV + S PVT K R +   E   EL   +  Y+
Sbjct: 268 CGCGLWERKGNRLRDVVQSLVAHQSKPVTIKCR-MGPDEENPELHKHIADYE 318


>UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3 precursor; n=2; delta proteobacterium MLMS-1|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3
           precursor - delta proteobacterium MLMS-1
          Length = 313

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 44/147 (29%), Positives = 64/147 (43%), Gaps = 2/147 (1%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           ++ AP+     LP RLL  +YGA + Y+E                +L+    V +   TI
Sbjct: 15  LVAAPLAGYSDLPFRLLCREYGAGLCYSE----------------MLSCHGLVRRQPATI 58

Query: 280 VFRTCEEEKKKVVLQL-GTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
                   ++ +++QL G   E      A L    +  IDINMGCP    +K G G AL+
Sbjct: 59  EMLATTAAERPLLMQLFGAEPEVMGEAAAILSRLPIDGIDINMGCPVRKVVKKGAGAALM 118

Query: 457 SKPDKAYQILKTLVDNL-SIPVTCKIR 534
             P+ A  I   +      +PVT KIR
Sbjct: 119 RDPELAAAITGAVTAAAGDLPVTVKIR 145


>UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
           Putative TIM-barrel protein, nifR3 family -
           Caldicellulosiruptor saccharolyticus (strain ATCC 43494
           / DSM 8903)
          Length = 328

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 43/153 (28%), Positives = 69/153 (45%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +N + K+ LAPM        R L  ++GAD+  TE +         ++  ++++      
Sbjct: 2   LNIKGKLFLAPMAGFTDKVFRSLCSRFGADVTVTEMVSAKAITMGSQKTKELISF----- 56

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLV--EHDVAAIDINMGCPKEFSIKG 435
                      E+EK K V   G+     A +  K++  E +   IDINMGCP    +K 
Sbjct: 57  ----------SEDEKIKGVQIFGSDPHVMA-EAVKIIQDEFEYDFIDINMGCPVPKVVKS 105

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G AL+  P  A +I++ +      PV+ KIR
Sbjct: 106 GEGSALMKNPSLAAKIVEEVAKVSRKPVSVKIR 138


>UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=12;
           Eutheria|Rep: tRNA-dihydrouridine synthase 3-like - Homo
           sapiens (Human)
          Length = 650

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++   K+ LAP+   G LP R +  ++GAD+   E  +    L+ +     +L       
Sbjct: 301 LDIRGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKR----- 355

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIKG 435
                     CE+      +QL         K A+L+   V    +DIN+GCP +   K 
Sbjct: 356 --------HQCEDI---FGVQLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKK 404

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G AL+++  K  QI++ +   L +P+T KIR
Sbjct: 405 GGGCALMNRSTKFQQIVRGMNQVLDVPLTVKIR 437


>UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG10463-PA - Nasonia vitripennis
          Length = 584

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +++++KI+LAP+  +G LP R +  ++GADI   E  +  + L+  R             
Sbjct: 286 IDWKDKIMLAPLTTVGNLPFRRICKEFGADITCGEMALAPRLLKGVRE------------ 333

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLV--EHDVAAIDINMGCPKEFSIKG 435
             +  +V R   E +    +Q+   +     +  +L+  E +V  +D+N+GCP +   K 
Sbjct: 334 --EWALVKR--HESEDLFGVQIAGNNPGVLTRCCQLLNDETEVDFVDLNVGCPIDLVYKQ 389

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G  +L++ +    ++K+  + L IP T K R
Sbjct: 390 GGGCGMLNRLNILESVVKSATEVLDIPFTVKTR 422


>UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24;
           Clostridia|Rep: Nitrogen regulation protein nifR3 -
           Clostridium tetani
          Length = 322

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 46/153 (30%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +  +  + LAP+  +  L  R L  + G  +VYTE       + +K  F D   T D   
Sbjct: 6   LELKGNVFLAPLAGVTDLAFRGLCKRMGCTLVYTE------MVSAKALFYDSDKTKD--- 56

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHD--VAAIDINMGCPKEFSIKG 435
                 + R  +EE    V   G   +  A  V K    +  V  IDINMGCP    +K 
Sbjct: 57  ------MLRFSKEELPIAVQIFGKEPDIMANVVEKYFNSNDNVCLIDINMGCPAPKIVKN 110

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G AL+  P  A  I++++    + PVT K R
Sbjct: 111 GEGSALMKNPKLASDIVESIKKVSTKPVTVKFR 143


>UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI;
           n=1; Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein yohI - Protochlamydia
           amoebophila (strain UWE25)
          Length = 326

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 27/72 (37%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
 Frame = +1

Query: 322 QLGTCDEARALKVAKLVEHDVAA-IDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLV 498
           QL   D     ++A+ VE   A  ID+N GCP       G G +LL +PD  Y++ K++V
Sbjct: 73  QLMGSDPELMAEMARAVERRGAQRIDLNCGCPSNTVTGRGAGSSLLKEPDHLYKVAKSMV 132

Query: 499 DNLSIPVTCKIR 534
           + +++PVT K+R
Sbjct: 133 EAVNVPVTAKLR 144


>UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 322

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 39/160 (24%), Positives = 76/160 (47%), Gaps = 5/160 (3%)
 Frame = +1

Query: 76  INMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELID--WKFLRSKRRFNDILNTV 249
           IN   E  I+LAP   +  L  R+L  KY   + +T  +    W    S R         
Sbjct: 10  INGLGEVPIVLAPQFEVNDLAFRMLVRKYNVKLCWTGMVNSHMWAIQPSSRN-------- 61

Query: 250 DYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSI 429
            Y         F+TC +++  +++Q+   DE+  +  AK ++     IDIN GC +  + 
Sbjct: 62  SY---------FQTCSQDRP-LIIQMSGNDESELIACAKDLQQFAVGIDINCGCTQHIAR 111

Query: 430 KGGMGVALLSKPDK---AYQILKTLVDNLSIPVTCKIRIL 540
           +G  G  +++  +K     +++K +V ++++P++ K R++
Sbjct: 112 RGQYGYFMVNNENKRKNVIEMVKNIVASINVPLSIKFRLI 151


>UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4;
           Leptospira|Rep: TRNA-dihydrouridine synthase -
           Leptospira borgpetersenii serovar Hardjo-bovis (strain
           JB197)
          Length = 339

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 30/96 (31%), Positives = 53/96 (55%), Gaps = 2/96 (2%)
 Frame = +1

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDV--AAIDINMGCPKEFSIKGGMGVALL 456
           F +   E+  + +QLG  D  +AL  +  +  D   + I++N+GCP +   +G  G  L+
Sbjct: 58  FLSYSPEELPLAIQLGG-DNPKALAESSKIGEDYGYSEINLNVGCPSDRVREGNFGACLM 116

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLE 564
             P++  +++  +  N+SIPVT K RI  + + TLE
Sbjct: 117 ETPERVAELVCAMDGNVSIPVTVKCRIGISGKETLE 152


>UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 312

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 46/162 (28%), Positives = 74/162 (45%), Gaps = 3/162 (1%)
 Frame = +1

Query: 64  LQFPINMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILN 243
           L+F  N   E+ I LAPM  +     R L  + G  + +T              F +  +
Sbjct: 3   LEFLENSKRESIIFLAPMADVNDYSFRKLCRQNGVSLCWT-------------GFINAHH 49

Query: 244 TVDYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEF 423
            V    Q D  + F T + EK  VV  LG+  E   +  AK VE+    I++N GC   F
Sbjct: 50  WVTRTKQRDRDVWFTTRDNEKNLVVQLLGSNLE-ELVSCAKDVENFCDMIELNCGCTHCF 108

Query: 424 SIKGGMGVALLSKP---DKAYQILKTLVDNLSIPVTCKIRIL 540
           + + G G  L+      D A  +++ L+ +++ PV+ KIR++
Sbjct: 109 ASRSGCGFFLIDTQKHRDSALILIQNLIKSINKPVSIKIRLI 150


>UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=7;
           Euteleostomi|Rep: tRNA-dihydrouridine synthase 3-like -
           Mus musculus (Mouse)
          Length = 637

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 42/153 (27%), Positives = 70/153 (45%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++   K+ LAP+   G LP R +  ++GAD+   E  +    L+ +     +L       
Sbjct: 288 LDISGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKR----- 342

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH--DVAAIDINMGCPKEFSIKG 435
                     CE+      +QL         K A+L+    DV  +DIN+GCP +   K 
Sbjct: 343 --------HPCEDI---FGVQLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKK 391

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G AL+++  K  QI++ +   L +P+T K+R
Sbjct: 392 GGGCALMNRSAKFQQIVRGVNGVLDVPLTVKMR 424


>UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781
           protein; n=3; Deuterostomia|Rep: PREDICTED: similar to
           MGC53781 protein - Strongylocentrotus purpuratus
          Length = 655

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++ ++K++LAP+  +G LP R +  K GADI   E  +    L+ +              
Sbjct: 278 LDVKDKLLLAPLTTVGNLPFRAVCKKLGADITCGEMAMCTNLLQGQ-------------- 323

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH--DVAAIDINMGCPKEFSIKG 435
            ++  ++ R   E+   V L  G  D     + A+L+    D+  IDIN+GCP +     
Sbjct: 324 SSEWALLRRHPSEDIFGVQLCGGFPDTMT--RCAELLNDRLDIDFIDINVGCPIDLVYHK 381

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G  L+++  K  +I++ +   L IP+T K+R
Sbjct: 382 GAGSGLMNRMGKFQEIVRGMSSVLDIPLTVKMR 414


>UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3
           family; n=23; Bacteroidetes/Chlorobi group|Rep:
           TIM-barrel protein, putative, NifR3 family -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 333

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 41/147 (27%), Positives = 71/147 (48%), Gaps = 1/147 (0%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           ++LAPM  +  +  R++  ++GAD+VY+E      FL +     D L     + Q  GT 
Sbjct: 13  LLLAPMEDVTDVAFRIMCKQFGADLVYSE------FLSA-----DAL-----IRQVAGTF 56

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALL 456
                +E ++ + +Q+   D A  ++ A+L E      ID+N GCP +     G G  +L
Sbjct: 57  RKMAIDESERPMAVQIYGRDVASMVEAARLCESAGPNLIDLNFGCPVKRVAGKGAGSGML 116

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI 537
                  +I + +V  + +PVT K R+
Sbjct: 117 RNIPLMIEITREVVKAVKLPVTVKTRL 143


>UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=20; Cyanobacteria|Rep: Dihydrouridine synthase
           TIM-barrel protein nifR3 - Synechococcus sp. (strain
           CC9902)
          Length = 356

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 26/49 (53%), Positives = 32/49 (65%)
 Frame = +1

Query: 391 IDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           IDINMGCP     K G G  L+  P+ A QIL+ +VD +SIPVT K R+
Sbjct: 121 IDINMGCPVRKIAKKGGGSGLIRDPNLATQILEAVVDAVSIPVTVKTRL 169


>UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 family;
           n=1; Pedobacter sp. BAL39|Rep: Probable TIM-barrel
           protein, NifR3 family - Pedobacter sp. BAL39
          Length = 335

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 40/149 (26%), Positives = 71/149 (47%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           E  ++LAPM  +   P R +  + G D++YTE +     +R   +    L+  +Y ++  
Sbjct: 12  EFPLLLAPMEDVSDPPFRFVCKQSGVDMMYTEFISSEGLIRDAAKSRAKLDIFEY-ERPI 70

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVA 450
           G  +F +  +  ++            A ++A +   D+  +DIN GCP +     G G A
Sbjct: 71  GIQIFGSEIDHMRE------------ATEIASMAGPDL--MDINYGCPVKQVACRGAGSA 116

Query: 451 LLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           LL   DK  ++ K +V+   +PVT K R+
Sbjct: 117 LLQDIDKMVEMTKAVVNATHLPVTVKTRL 145


>UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_158_49916_51304 - Giardia lamblia
           ATCC 50803
          Length = 462

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 35/131 (26%), Positives = 60/131 (45%)
 Frame = +1

Query: 106 LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVF 285
           +APMV    LP RLL  +YG ++ +T        + S +    +++ + + +  D  +V 
Sbjct: 21  IAPMVDGSELPYRLLTRRYGVELAWTPMHSTNTLVTSSKAMTQLVDELKHGESIDRPLVL 80

Query: 286 RTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKP 465
           +          L   T  +  A     +VE       +NMGCP+  +++G  G  L+   
Sbjct: 81  QLSGNNPSNFELAYNTLVQMGAGCCFDVVE-------LNMGCPQAVALRGKYGAYLMGHL 133

Query: 466 DKAYQILKTLV 498
           D A +IL+TLV
Sbjct: 134 DLAEEILRTLV 144


>UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n=1;
           Bdellovibrio bacteriovorus|Rep: Transcription regulator
           homolog yacF - Bdellovibrio bacteriovorus
          Length = 337

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 1/155 (0%)
 Frame = +1

Query: 73  PINMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVD 252
           P+     N  +LAPM  I     R    K  A +V TE L+               + ++
Sbjct: 3   PVEALKTNPFVLAPMAGITDHAFRTFIKKLDASVVVTE-LVS-------------ASGIE 48

Query: 253 YVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA-IDINMGCPKEFSI 429
           Y  ++D T+   + +E ++ + +QL   +     + A++ E D    +D+N GCP    +
Sbjct: 49  Y--KSDRTLKLMSFDESQRPIGIQLFGEEPEIVARAAQVAEADGCDFVDLNFGCPVPKVV 106

Query: 430 KGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           K G G A+L  P    +++ T+   + IP+T KIR
Sbjct: 107 KKGAGSAILKDPAAVQKMVSTVKAAIKIPLTIKIR 141


>UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 595

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 38/150 (25%), Positives = 68/150 (45%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           +  K++LAP+  +G LP R +   +GAD+  +E  + +   R ++    +L   +  D  
Sbjct: 233 FAEKLVLAPLTTVGNLPFRRICKSFGADVTLSEMAVVFNLNRLQKSEWSLLRRHESEDIF 292

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
              +     +E              A+AL+ +    +D   +DIN GCP E  +K G G 
Sbjct: 293 GIQLAVSRPQE----------AATFAQALEASGF-SYDF--LDINCGCPVEKIVKSGCGC 339

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
            L  + ++   ++++L    S PV  K RI
Sbjct: 340 GLWQRTERLRDVVESLAIYQSRPVAIKCRI 369


>UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1;
           Tetrahymena thermophila SB210|Rep: TIM-barrel protein,
           yjbN family - Tetrahymena thermophila SB210
          Length = 480

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +1

Query: 313 VVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILK 489
           VV+QLG  D     K AK+ E      +++N+GCP +    G  G  L+ +P+   +I++
Sbjct: 160 VVIQLGGNDPDNLAKAAKICEEIGYDEVNLNVGCPSDRVQSGKFGACLMKEPELVAEIMR 219

Query: 490 TLVDNLSIPVTCKIRI 537
            + +  SIPVT K R+
Sbjct: 220 KMKEACSIPVTVKCRL 235


>UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 321

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 38/153 (24%), Positives = 72/153 (47%), Gaps = 3/153 (1%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           E  + LAPMV +G +  R+L  ++G D+ +T  +   ++ RSK         ++Y     
Sbjct: 12  EYPVCLAPMVEMGDIAFRILCHRHGCDVCWTGMINGSQWNRSKTYRQQ---QIEY----- 63

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVA 450
                    EE + +V+Q+    +   L  AK +      IDIN+GC ++ + +G  G  
Sbjct: 64  --------SEEDRPLVIQISGSIDVDLLTTAKSMSEFGVPIDINLGCCQKVAKRGEYGYF 115

Query: 451 LLSKPDK---AYQILKTLVDNLSIPVTCKIRIL 540
           ++    K      ++K++   +++P+  KIR L
Sbjct: 116 MVDSEQKRQNVVNLIKSIPSEITVPLYVKIRAL 148


>UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep:
           H0613H07.1 protein - Oryza sativa (Rice)
          Length = 685

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 41/153 (26%), Positives = 72/153 (47%), Gaps = 2/153 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +++  K+ LAP+  +G LP R L    GADI   E  +    L+ +              
Sbjct: 328 IDFREKLYLAPLTTVGNLPFRRLCKTLGADITCGEMAMCTNLLQGQA------------- 374

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIKG 435
            ++  ++ R   E+   V +  G   +  A +  +LV+++ +   IDINMGCP +  +  
Sbjct: 375 -SEWALLRRHSSEDLFGVQI-CGAYPDTVA-RTVELVDNECSVDFIDINMGCPIDIVVNK 431

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G +LL+KP +   I++        P+T K+R
Sbjct: 432 GAGSSLLTKPMRIKSIVQAASTVTEKPLTVKVR 464


>UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 3 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 609

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 1/155 (0%)
 Frame = +1

Query: 73  PINMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVD 252
           P+++ Y  KI+ +P+  +G LP R L  K GAD+ Y+E  +    ++     ++      
Sbjct: 288 PLDL-YHKKIV-SPLTTVGNLPYRRLMRKLGADVTYSEMALAVPLIQGTN--SEWALPKA 343

Query: 253 YVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIK 432
           +  +  G  V   C +       Q     EA A  V+++ E     I++N GCP +   +
Sbjct: 344 HTSEFPGFGVQVACSK-----AWQAAKAAEALANSVSEISE-----INLNSGCPIDLLYR 393

Query: 433 GGMGVALLSKPDKAYQILKTL-VDNLSIPVTCKIR 534
            G G ALL  P +  + L  +   +  IP+T KIR
Sbjct: 394 QGSGSALLDNPARMIRCLNAMNYVSKDIPITVKIR 428


>UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1;
           n=15; Cyanobacteria|Rep: Probable tRNA-dihydrouridine
           synthase 1 - Synechocystis sp. (strain PCC 6803)
          Length = 355

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
 Frame = +1

Query: 295 EEEKKKVVLQLGTC-DEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDK 471
           +  +  + +QL  C  +  A    K V     ++DINMGCP     K G G +LL +P  
Sbjct: 93  DPRENPISIQLFDCRPDFMAEAAQKAVAQGAQSVDINMGCPVNKITKKGGGSSLLRQPAV 152

Query: 472 AYQILKTLVDNLSIPVTCKIRI 537
           A  I+KT+V  + +PVT K R+
Sbjct: 153 AEAIVKTVVAAVDVPVTVKTRL 174


>UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7;
           Chlamydiaceae|Rep: Predicted oxidoreductase - Chlamydia
           pneumoniae (Chlamydophila pneumoniae)
          Length = 335

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 41/153 (26%), Positives = 70/153 (45%), Gaps = 1/153 (0%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           N+   + I+ AP+      P R ++  Y   +++ E +     L +  R + +L   DY 
Sbjct: 9   NILLRSSIVYAPLAGFSDYPYRCMSALYQPGLMFCEMVKVEGILYAPERTSKLL---DY- 64

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKG 435
                        E  + +  QL   +   + + AK++E      ID+N GCP +   K 
Sbjct: 65  ------------NENMRPIGAQLCGSNPETSGEAAKILEGLGFDLIDLNCGCPTDKITKD 112

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G G  LL  P+   +IL  +++++SIPVT KIR
Sbjct: 113 GSGSGLLKTPELIGRILDKIINSVSIPVTVKIR 145


>UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 407

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
 Frame = +1

Query: 313 VVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKT 492
           ++ Q  + +       A+L+   V  ID+N GCP+ ++   G+G ALL KP+    +++ 
Sbjct: 152 LIAQFASPNAKSLADAAELISPYVDGIDLNCGCPQRWAYNEGIGCALLRKPELVRDMVRG 211

Query: 493 LVDNL--SIPVTCKIRILKTPEATLELVNKLI 582
           + D +    PV+ KIRI    E T +L++  +
Sbjct: 212 VKDRMGWGWPVSIKIRIDSEQEKTEQLISNAL 243


>UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4;
           Legionella pneumophila|Rep: Nitrogen regulation protein
           - Legionella pneumophila subsp. pneumophila (strain
           Philadelphia 1 /ATCC 33152 / DSM 7513)
          Length = 329

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 31/73 (42%), Positives = 38/73 (52%)
 Frame = +1

Query: 361 AKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRIL 540
           AKL       IDIN GCPK    K G G ALL  P K   I+  +   +SIP+T KIRI 
Sbjct: 94  AKLQSLGADLIDINCGCPKSKIRKKGAGSALLEDPQKLIAIISRVRAAISIPLTIKIRI- 152

Query: 541 KTPEATLELVNKL 579
           +  E  L L  ++
Sbjct: 153 QNNEKDLTLAKQI 165


>UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2;
           Proteobacteria|Rep: NifR3/Smm1 family protein -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 338

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 26/69 (37%), Positives = 40/69 (57%)
 Frame = +1

Query: 328 GTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNL 507
           G+C +  A       ++    IDINMGCP +   K   G ALL +P +  +I++++V+ +
Sbjct: 73  GSCPDELAFAAKVNADNGAQIIDINMGCPAKKVNKKLAGSALLREPAQVERIVQSVVNAV 132

Query: 508 SIPVTCKIR 534
            IPVT KIR
Sbjct: 133 DIPVTLKIR 141


>UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2;
           Aurantimonadaceae|Rep: Nitrogen regulation protein nifr3
           - Fulvimarina pelagi HTCC2506
          Length = 344

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
 Frame = +1

Query: 94  NKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           N++  AP+  I  +P R L+ ++GA +V +E +   +F++                  +G
Sbjct: 18  NRVFAAPLSGISDVPFRRLSRRFGAGLVVSEMVASGEFVKGAE---------------EG 62

Query: 274 TIVFRTCEEEKKKVVLQLGTCDEARALKVAK-LVEHDVAAIDINMGCPKEFSIKGGMGVA 450
            +  R   +      +QL   D     + A+ L +     IDINMGCP +  + G  G A
Sbjct: 63  KL--RALRDGPGVHTVQLAGRDPIWMEEAARRLADEGADLIDINMGCPAKKVVGGLSGSA 120

Query: 451 LLSKPDKAYQILKTLVDNL-SIPVTCKIRI 537
           L+ +PD A+ I++  V    + PV+ K+R+
Sbjct: 121 LMREPDLAFSIVEATVRGAGATPVSLKMRL 150


>UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein;
           n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep:
           Dihydrouridine synthase family protein - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 326

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 44/154 (28%), Positives = 66/154 (42%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           + ILAP+  I   P R LA   G  +VY+E       + S   F        Y  +  G 
Sbjct: 11  RTILAPLAGITDAPFRRLAKAAGCALVYSE------MVSSHGLF--------YQSEKTGA 56

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
           ++ RT  EE    V   G          A +       IDIN GC  +  +K G G AL+
Sbjct: 57  ML-RTTPEEAPFAVQIFGGKPAVMGRAAAMVQASGAHMIDINFGCSVKKILKSGAGAALM 115

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRILKTPEAT 558
                A ++++ + D +SIP+T K+R    P+ +
Sbjct: 116 KDLPLAAEVIQAVRDAVSIPLTIKMRSGWNPDGS 149


>UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase;
           n=2; Treponema|Rep: Probable tRNA-dihydrouridine
           synthase - Treponema pallidum
          Length = 340

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 43/158 (27%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++ +  +  AP+        R +A+++ A   YTE       + S+    D LNT   + 
Sbjct: 15  LSLKGNVFFAPVAGYSDSAFRSIAIEWEASFTYTE------MVSSEAMVRDSLNTKRLI- 67

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDV--AAIDINMGCPKEFSIKG 435
                   R    E    +   G+ + A   + AKL+      + IDIN GCP     K 
Sbjct: 68  --------RRASNETHYAIQIFGS-NPAVMAETAKLIVDSAQPSCIDINAGCPMPKITKT 118

Query: 436 GMGVALLSKPDKAYQILKTLVD-----NLSIPVTCKIR 534
           G G AL  +P + Y+++K + D     +  IPVT KIR
Sbjct: 119 GAGAALTREPTRLYEVVKAVADAVYAQDARIPVTVKIR 156


>UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to
           dihydrouridine synthase 4-like; n=3; Coelomata|Rep:
           PREDICTED: similar to dihydrouridine synthase 4-like -
           Tribolium castaneum
          Length = 451

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 3/162 (1%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRS-KRRFNDILNTVDYVDQTDGTI 279
           I APMVR   L  R L   Y  D+ YT  ++   F +S K R N+    ++     D  +
Sbjct: 27  ICAPMVRYSKLQFRNLVKSYNCDLCYTPMILADSFCKSGKARANEFTTNMN-----DTPL 81

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLS 459
           + +       KV   +G          A +V      +D+N GCP+ ++   G+G  +L 
Sbjct: 82  ITQFAAN---KVYDFVGA---------AYMVSPFCDGVDLNCGCPQRWAKLQGLGCIMLE 129

Query: 460 KPDKAYQILKTLVDNLSIP--VTCKIRILKTPEATLELVNKL 579
           KP+  Y ++K   + +  P  V+ K+R+ K    ++E+  +L
Sbjct: 130 KPEVIYDLVKQCRNVIPKPFTVSVKLRLQKDLRRSVEICRQL 171


>UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1;
           Thiomicrospira crunogena XCL-2|Rep: Dihydrouridine
           synthase - Thiomicrospira crunogena (strain XCL-2)
          Length = 320

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 41/145 (28%), Positives = 62/145 (42%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           I LAPM  I     R +  + GA    +E +   K LR   +     ++  + D+T    
Sbjct: 12  IALAPMAGITDRVYRDICRESGASYAVSEMVASKKQLRESAK-----SSTRHADKT---- 62

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLS 459
                 E   ++V  LGT  E                ID+NMGCP +       G AL+ 
Sbjct: 63  ------ETSPRIVQLLGTHPEELVDAALWQQSQGADIIDLNMGCPAKKVCDVAAGSALMG 116

Query: 460 KPDKAYQILKTLVDNLSIPVTCKIR 534
           +P++   I K+L + + +PVT KIR
Sbjct: 117 QPERVADIFKSLTEAIDLPVTVKIR 141


>UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Mariprofundus ferrooxydans PV-1|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Mariprofundus ferrooxydans PV-1
          Length = 341

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 1/149 (0%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           +N ++LAPM  I  LP R +  ++G  ++ TE +        + R   +    D      
Sbjct: 17  DNPLVLAPMAGITDLPFRRICKRFGVGLMVTEMIASRAVDMGRERTERMAELGD------ 70

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAK-LVEHDVAAIDINMGCPKEFSIKGGMGV 447
                     ++  V +Q+   D     + A+  V H    +DINMGCP +   K   G 
Sbjct: 71  ----------DEHPVSIQIAGSDPEFVTEAARWAVGHGADFVDINMGCPVKKICKQVAGS 120

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           A+L       ++L  +V  + +PVT KIR
Sbjct: 121 AMLRDEALVARVLAAVVAAVDVPVTLKIR 149


>UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 347

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 42/151 (27%), Positives = 68/151 (45%), Gaps = 3/151 (1%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           E   ++APM  +     R++  + GA++ Y+E +               +  + Y     
Sbjct: 16  EQPFLMAPMAGVTDPAYRIMCRRRGANLAYSEMVS--------------VAGLAYASNKT 61

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH---DVAAIDINMGCPKEFSIKGGM 441
             +V    +EE++  V   G+  E  A  VA + E     ++ IDINM CP    +  G 
Sbjct: 62  WRLVL-PADEEQQICVQLFGSKPEQFASAVAAVEERVGDRLSLIDINMACPARKVVTKGE 120

Query: 442 GVALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           G AL+  PD A +I++  V    +PVT KIR
Sbjct: 121 GSALMRTPDLAEKIVEAAVGAAHVPVTVKIR 151


>UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase B -
           Yersinia pestis
          Length = 321

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 26/54 (48%), Positives = 33/54 (61%)
 Frame = +1

Query: 391 IDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPE 552
           IDINMGCP +   +   G ALL  PD   QIL  +V+ + +PVT KIR   +PE
Sbjct: 94  IDINMGCPAKKVNRKLAGSALLQHPDLVKQILSAVVNAVDVPVTLKIRTGWSPE 147


>UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Thermus
           thermophilus|Rep: TRNA-dihydrouridine synthase - Thermus
           thermophilus (strain HB8 / ATCC 27634 / DSM 579)
          Length = 342

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 26/80 (32%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
 Frame = +1

Query: 301 EKKKVVLQLGTCDEARALKVAKLVE-HDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAY 477
           E+  + LQL   D     + A++ E      I++N+GCP E + +GG G  LL    +  
Sbjct: 56  EEHPIALQLAGSDPKSLAEAARIGEAFGYDEINLNLGCPSEKAQEGGYGACLLLDLARVR 115

Query: 478 QILKTLVDNLSIPVTCKIRI 537
           +ILK + + + +PVT K+R+
Sbjct: 116 EILKAMGEAVRVPVTVKMRL 135


>UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep:
           CG10495-PA - Drosophila melanogaster (Fruit fly)
          Length = 396

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 41/164 (25%), Positives = 77/164 (46%), Gaps = 5/164 (3%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           + APMVR   L  R L    G  + +T  +I           +D +N  +   Q +    
Sbjct: 26  VSAPMVRYSKLEFRRLVRLNGVQLAFTPMMI-----------SDSINNSEKARQNE---- 70

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
           F T  +++  ++ Q    D    +  A+L+   V  ID+N GCP+ +++  G G  +L +
Sbjct: 71  FSTGADDQP-LIAQFAAKDPTEFVTSAQLIYPYVDGIDLNCGCPQSWAMAKGYGCGMLRQ 129

Query: 463 PDKAYQILKTLVDNL--SIPVTCKIRILKTPEA---TLELVNKL 579
           P+  +Q+++ +   L     V+ K+R+L   E+   T++L  +L
Sbjct: 130 PELVHQVVQEVRRTLPGDFSVSVKMRLLGGEESLQRTIDLARQL 173


>UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domains
           plus Dus1p tRNA dihydrouridine synthase Tim barrel; n=2;
           Cryptosporidium|Rep: Ylr401cp-like protein with 2 CCCH
           domains plus Dus1p tRNA dihydrouridine synthase Tim
           barrel - Cryptosporidium parvum Iowa II
          Length = 707

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 43/153 (28%), Positives = 74/153 (48%), Gaps = 3/153 (1%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           + NK+ILAP+  +G LP R L LK+GAD+  +E ++           N+IL+      + 
Sbjct: 314 FRNKLILAPLTTVGNLPFRRLCLKFGADVTVSEMVL----------CNEILS-----GKA 358

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLV-EH-DVAAIDINMGCPKEFSIKGGM 441
               + +   EE K   +QL   +++  +K  + + EH +   IDIN  CP +     G 
Sbjct: 359 SELALLKKSPEE-KYFGIQLAGGNKSTIIKTGEFINEHCEFDFIDINAACPLKSLHDKGA 417

Query: 442 GVALLSKPDKAYQILKTLVDNLSIP-VTCKIRI 537
           G  L+ +  +   ++K L   +    VT K+R+
Sbjct: 418 GSILVDRVSELETMVKGLKKVMDGKLVTVKVRM 450


>UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus3 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 617

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 41/157 (26%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +++ ++ ILAP+  +G  P R L    GAD  Y+E  + +  ++  +    ++  ++Y  
Sbjct: 235 IDWRDRKILAPLTTVGNPPFRRLCGSLGADTFYSEMAMCYPLMQGHQPEWALVRGLNYER 294

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHD---VAAIDINMGCPKEFSIK 432
           +     + R     +  + +QL T    +A K A+++      V  +D+N GCP +   +
Sbjct: 295 E-----MMR--GGRRGILGVQLATGKLWQATKTAQVIAEQCDGVDFLDLNCGCPIDLVFR 347

Query: 433 GGMGVALLSKPDKAYQILKTLVDNLS--IPVTCKIRI 537
            G G +LL  P +  + L+ + D +S  IPVT K+R+
Sbjct: 348 QGAGSSLLENPGRLLRNLQGM-DAVSGQIPVTVKLRM 383


>UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_87,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 346

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = +1

Query: 313 VVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILK 489
           VV QLG  D  +  K A++ E      I++N+GCP E    G  G  L+ +P    Q +K
Sbjct: 67  VVCQLGGNDPEKLAKAAQIAEQAGFDEINLNVGCPSERVQDGAFGACLMKEPHLVAQCMK 126

Query: 490 TLVDNLSIPVTCKIRI 537
            + + + IP T K R+
Sbjct: 127 KMKEAVKIPCTLKCRL 142


>UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4;
           Bacteria|Rep: TIM-barrel protein, yjbN family -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 348

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
 Frame = +1

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLV-EHDVAAIDINMGCPKEFSIKGGMGVALLS 459
           F    +E+  V LQLG  D  +  +  ++  ++    I++N+GCP +   +G +G  L++
Sbjct: 78  FLDFNDEEHPVALQLGGSDPQQLAQATRIAGDYGYDEINLNVGCPSDRVQQGKIGAILMA 137

Query: 460 KPDKAYQILKTLVDNLSIPVTCKIRI 537
           +P+   + ++ +   +++PVT K RI
Sbjct: 138 EPELVARCVEAMQAEVTVPVTVKTRI 163


>UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 287

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 3/147 (2%)
 Frame = +1

Query: 106 LAPMVRIGTLPMR-LLALKYGADIVYTEELIDWKFLRSKR--RFNDILNTVDYVDQTDGT 276
           LAP+ + G  P R L A ++GA++V +E        +  R  R     +  D  D     
Sbjct: 6   LAPLTKGGNAPFRRLCASEFGAEVVVSEMAFARFLAKGARVERARVRRHEGDAGDCFGAQ 65

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
           I     EE     ++  G              E     +D+N GCP   + K G+G ALL
Sbjct: 66  IATNAIEEGVNAALIASG--------------EFGADFVDLNCGCPIHETWKRGLGAALL 111

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI 537
            KP K  ++++ +   + +P+T KIR+
Sbjct: 112 KKPAKLERLVEGIASRIDVPLTVKIRL 138


>UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine
           synthase-like protein C45G9.2; n=2; Caenorhabditis|Rep:
           Uncharacterized tRNA-dihydrouridine synthase-like
           protein C45G9.2 - Caenorhabditis elegans
          Length = 284

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 44/157 (28%), Positives = 67/157 (42%), Gaps = 3/157 (1%)
 Frame = +1

Query: 115 MVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVFRTC 294
           MVR   L  R L   Y  D+ +T  +    F+ S++  +  L+                C
Sbjct: 1   MVRYSKLAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSV---------------C 45

Query: 295 EEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKA 474
           E +   +V Q  T D     + A++V      +D+N GCPK      G G ALLSKP+  
Sbjct: 46  EGDSPLIV-QFATDDPFVLSEAAEMVYKCSTGVDLNCGCPKHDVRSKGFGSALLSKPELL 104

Query: 475 YQILKTLVDNLSIP---VTCKIRILKTPEATLELVNK 576
             +++     +  P   V+ KIRI    E T++L  K
Sbjct: 105 ADMVRQTRARIPDPDFSVSLKIRINHDIEKTVDLCRK 141


>UniRef50_UPI0000499494 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 515

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 37/156 (23%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++ + K+IL  +   G LP R +  ++G D+  TE ++    +  K              
Sbjct: 166 LDLKGKLILPSLCTFGNLPFRKVVKRFGCDVTMTEMIMAESLVEGKT------------- 212

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCD-EARALKVAKLVEHDVAAIDINMGCPKEFSIKGG 438
            ++  +V R   E+   + L +G     A+A +V   V+ D    ++N  CP ++  K G
Sbjct: 213 -SEWALVKRDSSEDIFGIQLCVGNSMLAAKACQVLNSVDCDF--YELNCACPIDYVYKKG 269

Query: 439 MGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKT 546
           MG  L+ +P +   +L  +      PV  K+R  K+
Sbjct: 270 MGAQLIERPKRIESLLHAMRSVTERPVAIKVRTGKS 305


>UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4;
           Thermotogaceae|Rep: Dihydrouridine synthase DuS -
           Fervidobacterium nodosum Rt17-B1
          Length = 322

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 44/144 (30%), Positives = 66/144 (45%)
 Frame = +1

Query: 106 LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVF 285
           LAPM  +   P R L L++GA   +T E+I  K +    + N+I     Y  + D     
Sbjct: 13  LAPMAGVTDYPFRKLCLQHGAYFAFT-EMISAKSVIINVKINEI-----YFPRQD----- 61

Query: 286 RTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKP 465
                EK +V +QL   D A   + A +V+     +D+N GCP    IK G G ALL   
Sbjct: 62  -----EKDRVGVQLFGSDYAELSEAAAIVQEKGLWVDLNAGCPVSKVIKKGAGSALLKDL 116

Query: 466 DKAYQILKTLVDNLSIPVTCKIRI 537
            +  ++++ +   L    T K RI
Sbjct: 117 GEFRKVVRAMRSVLK-RFTVKTRI 139


>UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Dihydrouridine
           synthase, DuS - Victivallis vadensis ATCC BAA-548
          Length = 343

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 47/166 (28%), Positives = 71/166 (42%), Gaps = 3/166 (1%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           EN +++AP+     LP R  A   G    +TE ++D             + ++ Y  +  
Sbjct: 15  ENALLMAPLSGFTDLPYRRAARAGGCRFAFTE-MVD-------------VASLTYARERS 60

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLV-EHDVAAIDINMGCPKEFSIKGGMGV 447
             ++ R  EEE   V  QL   D     + A +V E++ + +D N+GCP     K G G 
Sbjct: 61  AGMLRRGPEEEFLGV--QLVGADHEFIRRAADVVNEYEFSVVDFNLGCPVPKVAKKGAGA 118

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIRIL--KTPEATLELVNKL 579
            L    D A      + +    PVT KIRI+  + P  TL L   L
Sbjct: 119 ELGRHLDAALACFAIIAERSRHPVTAKIRIVDAEDPAPTLALAKGL 164


>UniRef50_A4YUQ6 Cluster: Putative tRNA-dihydrouridine synthase;
           n=4; Rhizobiales|Rep: Putative tRNA-dihydrouridine
           synthase - Bradyrhizobium sp. (strain ORS278)
          Length = 317

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
 Frame = +1

Query: 316 VLQLGTCDEARALKVAKLVEHDVA-AIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKT 492
           V+QL  C+     + AK+     A  IDINMGCP      G  G AL+   D A  +++ 
Sbjct: 51  VVQLAGCEAHWMAEGAKVAADGGADIIDINMGCPARHVTGGQSGSALMRDLDHALTLIEA 110

Query: 493 LVDNLSIPVTCKIRI 537
            V+ + +PVT K+R+
Sbjct: 111 TVEAVDVPVTLKMRL 125


>UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN
           family; n=4; Legionella pneumophila|Rep: Zinc binding
           TIM barrel protein, YjbN family - Legionella pneumophila
           subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 /
           DSM 7513)
          Length = 334

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
 Frame = +1

Query: 226 FNDILNTVDYVDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHD-VAAIDIN 402
           + ++  T    +  D  + F + E     + +QLG  D++  +K A + E      I++N
Sbjct: 40  YTEMQTTGAVQNNPDRALYFNSVEHP---LAIQLGGADKSALVKCAIIAEQKGFNEINLN 96

Query: 403 MGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           +GCP +    G  G  L+ +P+     ++ +   + IPVT K RI
Sbjct: 97  LGCPSDKVQAGRFGACLMKEPEHVADCIRAIKQVVGIPVTAKTRI 141


>UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein;
           n=3; Desulfovibrio|Rep: Dihydrouridine synthase family
           protein - Desulfovibrio desulfuricans (strain G20)
          Length = 376

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
 Frame = +1

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHD-VAAIDINMGCPKEFSIKGGMGVALL 456
           VF    EE   +V QL   D       A+ VE +    +DINMGC     +K G G  LL
Sbjct: 105 VFSWRPEELPALVCQLFGADPQDMAAAARRVESEGFFGVDINMGCSVAPIVKKGCGADLL 164

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI--LKTPEATLELVNKL 579
             P++A +++  +   +S+PV  K+R      PE  + L  +L
Sbjct: 165 RDPERAVRMVDAVRRAVSVPVFVKMRTGWSPDPEPAVNLARRL 207


>UniRef50_Q5KC68 Cluster: TRNA dihydrouridine synthase, putative;
           n=2; Filobasidiella neoformans|Rep: TRNA dihydrouridine
           synthase, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 725

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +N+E    LAP+  +G LP R L + YGA I  +E  +    +              Y  
Sbjct: 354 LNWEGGRYLAPLTTVGNLPFRRLCVDYGATITVSEMALAQPLV--------------YGA 399

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA------IDINMGCPKEF 423
           + +  +V R   E +K   +Q+      R +  A+++ + +        +D+NMGCP + 
Sbjct: 400 KEEWALVRR--HESEKMFGVQVAGGFPNRMVPAAEVIANTIGKGGGVDFVDVNMGCPIDL 457

Query: 424 SIKGGMGVALLSKPDKAYQILKTLVDNL-SIPVTCKIR 534
               G G AL+  P +  ++L  +   L  IP+T K R
Sbjct: 458 VFNQGAGSALMDSPGRLGKLLVGMNRALGDIPLTVKFR 495


>UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22;
           Alphaproteobacteria|Rep: Nitrogen regulation protein -
           Bradyrhizobium japonicum
          Length = 371

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
 Frame = +1

Query: 316 VLQLGTCDEARALKVAKLVEHDVA-AIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKT 492
           V+QL  C+     + A++ E + A  IDINMGCP      G  G AL+   D A  ++  
Sbjct: 105 VVQLAGCEAHWMAEGARIAEAEGADIIDINMGCPARHVTGGQSGSALMRDLDHAVGLIDA 164

Query: 493 LVDNLSIPVTCKIRI 537
            +  + +PVT K+R+
Sbjct: 165 TIAAVKVPVTLKMRL 179


>UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1;
           Polynucleobacter sp. QLW-P1DMWA-1|Rep: Dihydrouridine
           synthase, DuS - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 347

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
 Frame = +1

Query: 298 EEKKKVVLQLGTC---DEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPD 468
           +++  VVLQLG     D AR+ ++A+   +D   ID+N GCP E   +G  G  L+++P 
Sbjct: 45  QDQHPVVLQLGGSEPNDLARSAELAQQWGYD--EIDLNCGCPSERVQRGAFGACLMAEPK 102

Query: 469 KAYQILKTLVDNLSIPVTCKIRI 537
                +K + + + IP++ K R+
Sbjct: 103 LVADCVKAMQNAVDIPISVKHRL 125


>UniRef50_A3VNG3 Cluster: Dihydrouridine synthase TIM-barrel
           protein; n=5; Alphaproteobacteria|Rep: Dihydrouridine
           synthase TIM-barrel protein - Parvularcula bermudensis
           HTCC2503
          Length = 368

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 46/152 (30%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           E  +ILAPM  I  LP R  AL+ GA +V +E +   +++R               ++ D
Sbjct: 27  ERPVILAPMSGITDLPFRRAALRAGAPLVVSEMVASEEWVR---------------ERPD 71

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALK--VAKLVEHDVAAIDINMGCPKEFSIKGGM- 441
             +       +   V+   G   EAR ++   AK        IDINMGCP    + G + 
Sbjct: 72  VALRAALPTGDSLNVIQLAGR--EARWMREGAAKAEALGADIIDINMGCPAR-KVTGLLS 128

Query: 442 GVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           G AL+   D A  ++K  +   S PVT K+R+
Sbjct: 129 GSALMRDVDHALSLIKATLSGTSRPVTLKMRL 160


>UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 493

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 35/132 (26%), Positives = 61/132 (46%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           +I APMVR      R +   +G  + YT  L+   F++S    +                
Sbjct: 98  LIQAPMVRCSRPAFRQVCRAWGTRVSYTHMLMAESFVKSPHARH---------------A 142

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLS 459
            F   E E + +V QL       A + A L+      ID+N GCP+ +++K G+G ALL 
Sbjct: 143 EFARYEGENR-LVAQLAAKSGPAAAQAALLLRPYCDGIDLNCGCPQRWAMKEGIGAALLD 201

Query: 460 KPDKAYQILKTL 495
           +P++   +++++
Sbjct: 202 QPERVADMVRSI 213


>UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=2; Anaeromyxobacter|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Anaeromyxobacter
           dehalogenans (strain 2CP-C)
          Length = 352

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 39/149 (26%), Positives = 61/149 (40%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           +  +  LAP+  +   P R +  + GA   YTE       + +    +  L T  Y+D+ 
Sbjct: 8   FPGRYFLAPLAGVSDRPFRAICRRMGASFAYTE------MVSAHGLMHGALQTSSYLDRE 61

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
                F       +  VL       AR   VA  V+     ID+NM CP +     G G 
Sbjct: 62  PDEDPFAVQIFASEPDVL-------ARGAVVA--VQAGAGMIDVNMACPVKKVCGSGAGA 112

Query: 448 ALLSKPDKAYQILKTLVDNLSIPVTCKIR 534
           A+   P K  + ++ +   + +PVT KIR
Sbjct: 113 AMGRDPRKVEEAVRAIRAAVPVPVTVKIR 141


>UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1;
           Saccharophagus degradans 2-40|Rep: Dihydrouridine
           synthase, DuS - Saccharophagus degradans (strain 2-40 /
           ATCC 43961 / DSM 17024)
          Length = 318

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 42/150 (28%), Positives = 62/150 (41%), Gaps = 3/150 (2%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMR-LLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           +I LAPM  +    MR +++   G DI  TE +     +   + F      +D   +T  
Sbjct: 2   RIFLAPMEGVVDHHMRNIISSVGGVDICVTEFIRVTDHVLPNKIFKKACPELDENSETPA 61

Query: 274 TIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVAL 453
                 C       V  LG+   A A   A+  E    AID+N GCP +   +   G  L
Sbjct: 62  LYRGAHCPVR----VQLLGSNPSALAANAARAAELGAVAIDLNFGCPAKTVNRHKGGACL 117

Query: 454 LSKPDKAYQILKTL--VDNLSIPVTCKIRI 537
           L + D  + I+  +      S PVT KIR+
Sbjct: 118 LDETDTVFDIVNAVRKATPASTPVTAKIRL 147


>UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1;
           Ruminococcus flavefaciens|Rep: Putative dihydrouridine
           synthase - Ruminococcus flavefaciens
          Length = 332

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 1/153 (0%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           N+       LAPM  +     RL+  +YGA  V +E ++  K              + Y 
Sbjct: 9   NVTIPRTAALAPMAGVADRAYRLMCKRYGAAYVVSE-MVSAK-------------GICYS 54

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGG 438
           D+    +   T EEE+   V   G+  +  A  V  ++++    IDINMGCP    +  G
Sbjct: 55  DRKTAELCTVT-EEERPMAVQLFGSEPDFMAEAVKIVLDYRPDIIDINMGCPVPKVVGTG 113

Query: 439 MGVALLSKPDKAYQILKTLVDNL-SIPVTCKIR 534
            G AL+  P  A  I +  V      PVT KIR
Sbjct: 114 AGSALMKDPALAAAITEAAVKAAGDTPVTVKIR 146


>UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21;
           Cyanobacteria|Rep: TRNA-dihydrouridine synthase A -
           Synechococcus sp. (strain RCC307)
          Length = 335

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
 Frame = +1

Query: 304 KKKVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQ 480
           +K + LQLG  D A   + A+L E      I++N+GCP     KG  G  L+++P +  +
Sbjct: 67  EKPIALQLGGDDPALLAEAAELAERWGYDEINLNVGCPSPKVKKGRFGACLMAEPQQVAR 126

Query: 481 ILKTLVDNLSIPVTCKIRI 537
            ++ +     +PVT K RI
Sbjct: 127 CVEAMGAACRLPVTVKHRI 145


>UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1;
           Dichelobacter nodosus VCS1703A|Rep: Dihydrouridine
           synthase - Dichelobacter nodosus (strain VCS1703A)
          Length = 318

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 2/162 (1%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           ++LAPM  I  LP R L  ++G+     E ++D +                ++   +  +
Sbjct: 14  VLLAPMAGISDLPYRSLCQRFGSHYTIAE-MVDAR--------------PQFLAMPESQL 58

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALL 456
             +  ++ +   ++QL   D     + A++++      IDINMGCP +   K   G ALL
Sbjct: 59  RLQFDDDARFPKIVQLVGGDPYLMAETAQVMQALGCDVIDINMGCPAKKVGKQNAGSALL 118

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI-LKTPEATLELVNKL 579
           S   +  +IL  +   +SIPVT K R+       T+E V K+
Sbjct: 119 SDLPQVEKILAQVTRVVSIPVTLKTRLGFNEQTMTIETVAKI 160


>UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1;
           Candidatus Ruthia magnifica str. Cm (Calyptogena
           magnifica)|Rep: TIM-barrel protein, yjbN family - Ruthia
           magnifica subsp. Calyptogena magnifica
          Length = 322

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
 Frame = +1

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALLS 459
           F  CE     +VLQLG  +     + AK+ +      I+IN+GCP         GV L+ 
Sbjct: 54  FNVCEHP---LVLQLGGSEPKEMAQAAKIAQDWGYNEININVGCPSNRVQSSNFGVCLMQ 110

Query: 460 KPDKAYQILKTLVDNLSIPVTCKIRI-LKTPEATLELVNKLITYQ 591
            P    Q +  +   + +P+T K RI +   ++  ELVN + T +
Sbjct: 111 TPQVVAQCVDAMRQMVDVPITVKSRIGVDNMDSYDELVNFVATVE 155


>UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Moorella thermoacetica ATCC 39073|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Moorella thermoacetica (strain ATCC 39073)
          Length = 334

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 43/148 (29%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           +I+APM        RLLA + GA + YTE +     + + +  + +L+            
Sbjct: 16  LIMAPMAGYTDRVFRLLAREAGAALTYTEMISAQGLIYNNKNTHALLDL----------- 64

Query: 280 VFRTCEEEKKKVVLQL-GTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
                + E   V +QL G   E  A      V    A ID+NMGCP    +K G G AL+
Sbjct: 65  -----KGEPGPVAVQLFGREPEIMAAATRIAVAAGAAIIDLNMGCPTPKIVKNGEGSALM 119

Query: 457 SKPDKAYQILKTLVDNLS-IPVTCKIRI 537
               +A  I+  +V     +PVT K+R+
Sbjct: 120 RDLPRAAAIVAAMVRAAGPVPVTVKMRL 147


>UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=5; Chloroflexi (class)|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Chloroflexus
           aurantiacus J-10-fl
          Length = 407

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
 Frame = +1

Query: 301 EKKKVVLQLGTCDEARALKVAKLVEHDVA-AIDINMGCPKEFSIKGGMGVALLSKPDKAY 477
           E++ + +Q+   D       A++VE   A  IDIN GCP      GG G ALL    K  
Sbjct: 137 EERPLTMQISGNDPDLVANAARVVEQLGADIIDINCGCPSPKVTGGGHGSALLRDLPKME 196

Query: 478 QILKTLVDNLSIPVTCKIR 534
           ++L+ + + + IPVT K R
Sbjct: 197 RLLRAVREAVQIPVTLKFR 215


>UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30;
           Bacteria|Rep: TIM-barrel protein, yjbN family -
           Shewanella sp. (strain W3-18-1)
          Length = 343

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
 Frame = +1

Query: 298 EEKKKVVLQLGTCDEARALKVAKLV-EHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKA 474
           +E+  + LQLG  +     + AKL  E     +++N+GCP +    G  G  L+++P+  
Sbjct: 73  QEEHPLALQLGGSNPQDLARCAKLAAERGYDEVNLNVGCPSDRVQNGRFGACLMAEPELV 132

Query: 475 YQILKTLVDNLSIPVTCKIRI 537
            + +  +   + IPVT K RI
Sbjct: 133 AECVDAMKQVVDIPVTVKTRI 153


>UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: NifR3
           protein - Deinococcus radiodurans
          Length = 406

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 1/160 (0%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           +LAPM      PMR LA + GA +    E+I  + L        +L +     + +   +
Sbjct: 95  VLAPMAGYSDAPMRQLAAEQGA-LWTVSEMISARGL--------VLGS-----EQESLSL 140

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDV-AAIDINMGCPKEFSIKGGMGVALLS 459
            R    E+ + V   G   +  A  V K       AAID+N+GCP    ++G  G  LL 
Sbjct: 141 GRPYPGEQGRAVQLFGADPDVLADAVGKAEAWFAPAAIDLNLGCPVP-KVRGKGGACLLQ 199

Query: 460 KPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKL 579
            P+ AY++++ +     + V+ KIR+      ++E+   L
Sbjct: 200 TPEVAYELVRAMRQATGLDVSAKIRLGWDENRSVEIAQGL 239


>UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10;
           Proteobacteria|Rep: TIM-barrel protein, yjbN family -
           Methylococcus capsulatus
          Length = 327

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 40/146 (27%), Positives = 63/146 (43%), Gaps = 1/146 (0%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           +ILAPM  +  LP R L  ++GA +  +E +     L++ R+                  
Sbjct: 12  VILAPMAGVTDLPFRRLCRQFGAGLAVSEMISASPALQATRKSR---------------- 55

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAK-LVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
           + +    E   + +Q+   D     + A+  V+     IDINMGCP +       G ALL
Sbjct: 56  LRQDHRGEPGPISVQIVGADPREMAEAARRTVDLGADIIDINMGCPAKKVCNVAAGSALL 115

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIR 534
                   IL+ +V  + +PVT KIR
Sbjct: 116 RDEKLVANILEAVVQAVPVPVTLKIR 141


>UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034,
           putative; n=7; Plasmodium|Rep: Uncharacterized protein
           family UPF0034, putative - Plasmodium yoelii yoelii
          Length = 531

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +1

Query: 313 VVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPK-EFSIKGGMGVALLSKPDKAYQIL 486
           +V QLG  D     + A LVE      I+IN+GCP  + + KG  G  L+  P     I+
Sbjct: 210 IVCQLGGSDPTSLSEAAILVEQAGYDEININVGCPSTKVANKGAFGAYLMKNPQLVKNIV 269

Query: 487 KTLVDNLSIPVTCKIR 534
             +   + IPVT KIR
Sbjct: 270 YEIKKKVQIPVTVKIR 285


>UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_38_15456_16676 - Giardia lamblia
           ATCC 50803
          Length = 406

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
 Frame = +1

Query: 307 KKVVLQLGTCDEARALKVAKLVEHD------VAAIDINMGCPKEFSIKGGMGVALLSKPD 468
           +K++LQL   + +     A+L+ HD      + A+DIN+GCP   +   G G  +     
Sbjct: 113 EKIILQLCGNNPSTFRAAAELL-HDSPIASQLVALDINLGCPASCASSKGYGFYVAQNWP 171

Query: 469 KAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
             +QI+         PVTCKIR L + E T++ +  L+
Sbjct: 172 LVHQIISETSSARLFPVTCKIRPLNSIEKTIDYMVLLV 209


>UniRef50_UPI000023CFE7 Cluster: hypothetical protein FG01258.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG01258.1 - Gibberella zeae PH-1
          Length = 362

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 32/118 (27%), Positives = 55/118 (46%)
 Frame = +1

Query: 106 LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVF 285
           LAPMVR G L  R    KYG D+ ++  ++  +F RS            +   +D +  F
Sbjct: 29  LAPMVRYGKLAFRQTVHKYGVDLCWSPMILAKEFNRS-----------SFARDSDWS--F 75

Query: 286 RTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLS 459
            T E ++   ++Q G        + + LV      +D+N GCP+ ++    +G AL++
Sbjct: 76  ST-EPKQPPTIVQFGANVPLELARASALVAPSSQGVDLNCGCPQSWACAETLGAALMN 132


>UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2;
           Planctomycetaceae|Rep: Putative uncharacterized protein
           - Rhodopirellula baltica
          Length = 364

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 4/84 (4%)
 Frame = +1

Query: 298 EEKKKVVLQLGTCDEARALKVAKLV--EHDVAAIDINMGCP-KEFSIKGGMGVALLSKPD 468
           +E + + +Q+   D     KV + +  E+ V+ +DIN GCP ++ + K   G  LL +P+
Sbjct: 85  DEPRPLAVQIWDNDPETMAKVGRRLAEEYRVSVVDINFGCPVRQVTEKAHSGSYLLREPN 144

Query: 469 KAYQILKTLVDNLS-IPVTCKIRI 537
           + + I+  LV   +  PVT KIR+
Sbjct: 145 RMHAIISRLVQVCAPTPVTAKIRL 168


>UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 297

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = +1

Query: 355 KVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKI 531
           + AK++E      +D+N GCP +   K G G  LL  P+   +I+  +V  + IPVT KI
Sbjct: 41  QAAKIIEELGFDIVDLNCGCPVDKITKDGSGSGLLKTPELIGEIVCNMVSAVKIPVTVKI 100

Query: 532 R 534
           R
Sbjct: 101 R 101


>UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1;
           Marinomonas sp. MWYL1|Rep: Dihydrouridine synthase DuS -
           Marinomonas sp. MWYL1
          Length = 335

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           LG+  E  A       +     ID+N GCP +     G G  LL  PD  Y I+  + D 
Sbjct: 88  LGSNAELMAESALNATKAGAKHIDVNFGCPAKRVNGHGGGSVLLQTPDALYDIMSAIRDT 147

Query: 505 L--SIPVTCKIRILKTPEATL 561
           L   IPV+ KIR+    EA L
Sbjct: 148 LPSDIPVSAKIRLGFEDEALL 168


>UniRef50_Q4Q669 Cluster: Dihydrouridine synthase (Dus), putative;
           n=3; Leishmania|Rep: Dihydrouridine synthase (Dus),
           putative - Leishmania major
          Length = 661

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 20/54 (37%), Positives = 32/54 (59%)
 Frame = +1

Query: 388 AIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTP 549
           A+D+N+GCP+  + +G  G  L+   +  + I+ TL   L +PVT KIR+   P
Sbjct: 283 AVDVNLGCPQGIARRGHYGSFLMEDWELIHTIVHTLHVELEVPVTVKIRVFDHP 336


>UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase A -
           Xylella fastidiosa
          Length = 340

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
 Frame = +1

Query: 304 KKKVVLQLGTCDEARALKVAKL-VEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQ 480
           ++ V LQLG  + A   K A++ V+   + I++N GCP +    G  G  L+ +P     
Sbjct: 69  EQPVALQLGGSEPALLAKAARIAVDWGYSEINLNCGCPSDRVQAGSFGARLMREPALVAD 128

Query: 481 ILKTLVDNLSIPVTCKIRI 537
            +  +   +S+PVT K R+
Sbjct: 129 CVAAMAAVVSVPVTVKCRL 147


>UniRef50_A5WG83 Cluster: TIM-barrel protein, yjbN family; n=4;
           Moraxellaceae|Rep: TIM-barrel protein, yjbN family -
           Psychrobacter sp. PRwf-1
          Length = 348

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
 Frame = +1

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVA-KLVEHDVAAIDINMGCPKEFSIKGG 438
           +TD  + + T E     +VLQLG  D +   + A +  +     ++IN+GCP +      
Sbjct: 63  KTDRLLRYDTLEHP---LVLQLGGADISEMTQCAVEAQKRGFNEVNINVGCPSDRVQHNK 119

Query: 439 MGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           +G  L+++PD    +++ +  ++ IPVT K RI
Sbjct: 120 IGACLMAEPDTVAALVRNMQAHVDIPVTVKHRI 152


>UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 342

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 32/127 (25%), Positives = 52/127 (40%)
 Frame = +1

Query: 109 APMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVFR 288
           APMVR   L  R    +YG D+ +T  ++  +F RS           D+      T    
Sbjct: 35  APMVRYSKLAFRETVAQYGVDLCWTPMILAKEFNRSV-----FARDSDFTTSPTST---- 85

Query: 289 TCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPD 468
                    + Q G C      +   L+   +  IDIN GCP+ ++    +G AL+ K +
Sbjct: 86  -------PTIAQFGVCSPLEISRSTTLIAPYINGIDINCGCPQSWACACSIGAALMHKRE 138

Query: 469 KAYQILK 489
              +++K
Sbjct: 139 LVAEMVK 145


>UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4;
           Bifidobacterium|Rep: Possible NifR3-like protein -
           Bifidobacterium longum
          Length = 414

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 43/160 (26%), Positives = 70/160 (43%), Gaps = 7/160 (4%)
 Frame = +1

Query: 79  NMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           N+     ++L+PM  +   P R++  +YG D +Y  E+I  + L +              
Sbjct: 42  NITVPTPVVLSPMAGVTNWPFRVICEEYGPDGLYVAEMITARALVAHN------------ 89

Query: 259 DQTDGTIVFRTCEEEKKKVV--LQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFS 426
                    R C   K + +  LQL   + +   + AK+V     A  +D+N GCP    
Sbjct: 90  -----PKALRLCHFAKSEKIRSLQLYGVNPSITEQAAKIVVDGNMADHVDLNFGCPVPKV 144

Query: 427 IKGGMGVALLSKPDKAYQILKTLV---DNLSIPVTCKIRI 537
            + G G AL  K D   ++L+ +V   +   IPVT KIR+
Sbjct: 145 TRRGGGSALPWKTDIFTELLQRVVAVCEPAGIPVTAKIRV 184


>UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase;
           n=9; Epsilonproteobacteria|Rep: Probable
           tRNA-dihydrouridine synthase - Helicobacter pylori
           (Campylobacter pylori)
          Length = 328

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 41/155 (26%), Positives = 69/155 (44%), Gaps = 3/155 (1%)
 Frame = +1

Query: 82  MNYENK--IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDY 255
           M+++NK  + LAP+     LP R +  K+G D+  +E +     + +  + + +L     
Sbjct: 1   MDFKNKKWLFLAPLAGYTDLPFRSVVKKFGVDVTTSEMVSSHSLVYAFDKTSKMLEKSPL 60

Query: 256 VDQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKG 435
            D     I        K+ VV +        A++    +EH V  ID N GCP       
Sbjct: 61  EDHFMAQI-----SGSKESVVKE--------AVEKINALEH-VNGIDFNCGCPAPKVANH 106

Query: 436 GMGVALLSKPDKAYQILKTLVDNLSIPVT-CKIRI 537
           G G  LL   +   ++LKT+ +N S  +T  K+R+
Sbjct: 107 GNGSGLLKDLNHLVKLLKTIRENTSKKITSVKVRL 141


>UniRef50_Q9A7I4 Cluster: Nitrogen regulation protein Nifr3; n=2;
           Caulobacter|Rep: Nitrogen regulation protein Nifr3 -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 315

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
 Frame = +1

Query: 391 IDINMGCP-KEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           ID+N GCP KE +     G AL+ +PD A  ++   V+ + +PVT K+R+
Sbjct: 78  IDLNFGCPAKEVAAGAACGSALMREPDLAEALVAAAVEAVDVPVTVKMRL 127


>UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3;
           Planctomycetaceae|Rep: Putative uncharacterized protein
           - Rhodopirellula baltica
          Length = 374

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 45/156 (28%), Positives = 70/156 (44%), Gaps = 4/156 (2%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTI 279
           ++ A +     LPMR++A ++ A     E ++D +FL S  +     + +D  D      
Sbjct: 40  VVQAALSGYSDLPMRVIARRHSASYTICEVMLD-QFLLSLTKREKTRHFLDIAD------ 92

Query: 280 VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLS 459
                 EE       +G   E  +    KLVE     ID+N GCP +  +    G   LS
Sbjct: 93  ------EEHPVGGQLMGAEPEQFSAGALKLVEAGFDVIDVNFGCPVKKVLGRCRGGFHLS 146

Query: 460 KPDKAYQILKTLVDNL--SIPVTCKIR--ILKTPEA 555
           +P  A +IL+   D +   IPVT K+R  +  TPE+
Sbjct: 147 QPAVAIEILRRTRDVVPDHIPVTVKMRRGMDDTPES 182


>UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1;
           uncultured Acidobacteria bacterium|Rep: Putative
           uncharacterized protein - uncultured Acidobacteria
           bacterium
          Length = 355

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
 Frame = +1

Query: 106 LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVF 285
           +APM +   LP R L ++ GA I  +E  +  + L+ KR              ++  ++ 
Sbjct: 1   MAPMTKGSNLPYRRLCVELGARITVSEMTLARR-LKQKRN-------------SEFALIR 46

Query: 286 RTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKP 465
           R   E    V L     DE  A   A +       +DIN GCP ++  + G+G ++  +P
Sbjct: 47  RFPGEPCFGVQLAGNKPDET-AWAAALVESRGADFVDINFGCPIDYFTRKGLGASIGRQP 105

Query: 466 DKAYQILKTLVDNL-SIPVTCKIRI 537
            +  ++++ +  ++ +IPVT KIR+
Sbjct: 106 QRMRRLVEAIKGSVTNIPVTAKIRL 130


>UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Opitutaceae bacterium TAV2|Rep: Putative TIM-barrel
           protein, nifR3 family - Opitutaceae bacterium TAV2
          Length = 389

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 33/151 (21%), Positives = 69/151 (45%), Gaps = 3/151 (1%)
 Frame = +1

Query: 94  NKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDG 273
           + + L+P+     LPMRL   + G         + W          D++N    ++++ G
Sbjct: 10  SNLFLSPLAGYTNLPMRLTVRELGG--------LGWAT-------TDLVNARSLIERSKG 54

Query: 274 TI-VFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVA 450
            + +  T   ++   +   G+  E          E    ++D+NMGCP +  +  G G A
Sbjct: 55  AMKLVETAPGDQPLAIQLFGSVPEEMRDAAVICKELGAQSVDVNMGCPVKKVVGIGGGAA 114

Query: 451 LLSKPDKAYQILKTLVDNL--SIPVTCKIRI 537
           ++++ +K   +++ +V+ +   IPVT K+R+
Sbjct: 115 MMTELNKTAALVRGMVEAVGNKIPVTAKMRL 145


>UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 608

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 42/161 (26%), Positives = 72/161 (44%), Gaps = 3/161 (1%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +++++K+ LAP+  +G LP R +    GADI   E  +    L+                
Sbjct: 243 IDFKDKLYLAPLTTVGNLPFRRVCKTLGADITCGEMALCTSLLQGL-------------- 288

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH--DVAAIDINMGCPKEFSIKG 435
            ++  ++ R   E+   V +  G  D     +  +L+E   DV  IDINMGCP +   + 
Sbjct: 289 PSEWALLRRHKSEDIFGVQICGGYPDSVT--RCCQLLEDTIDVDFIDINMGCPIDSVCQK 346

Query: 436 GMGVALLSKPDKAYQILKTLVDNL-SIPVTCKIRILKTPEA 555
           G G  +L KP K   +++     L    +T K R+  T ++
Sbjct: 347 GYGSMMLEKPKKMETVIRAASAALGKCSLTFKTRMAYTDKS 387


>UniRef50_Q7R684 Cluster: GLP_574_116690_118078; n=1; Giardia
           lamblia ATCC 50803|Rep: GLP_574_116690_118078 - Giardia
           lamblia ATCC 50803
          Length = 462

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 51/196 (26%), Positives = 80/196 (40%), Gaps = 21/196 (10%)
 Frame = +1

Query: 64  LQFPINMNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILN 243
           +Q+P         ILAPMVR     +R LA   GA  VYT  ++    LR      D+ N
Sbjct: 1   MQWPSPSTLYTGPILAPMVRASFPGIRALAAALGASAVYTGAIVG-DSLRDVVTEVDLSN 59

Query: 244 TVDYVDQTDGTIVFRTCE---------------EEKKKVVLQLGTCDEARALKVAKLVEH 378
            +  +  T  +    +C                E    +V+QL   +     K+  ++  
Sbjct: 60  MIAKISTTRRSAGSPSCVIISVPIQATETPGQFEPAIPLVVQLTVNEYDDVDKICSILAP 119

Query: 379 DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAY-QILKTLVD-----NLSIPVTCKIRIL 540
               ID+N+GC  +F++ GG G  L+ K +    + LK L          I  + K R+L
Sbjct: 120 WCVGIDLNLGCGAQFAVSGGRGQRLVDKAENVIARFLKALQQIEDSGGRRISFSIKQRLL 179

Query: 541 KTPEATLELVNKLITY 588
            + E   E VNK+  +
Sbjct: 180 GSVE---ETVNKMCAF 192


>UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2;
           Sinorhizobium|Rep: Dihydrouridine synthase DuS -
           Sinorhizobium medicae WSM419
          Length = 385

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
 Frame = +1

Query: 313 VVLQLGTCDEARALKVAKLVE-HDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILK 489
           V LQLG  D  +  + A++ E +    I++N+GCP +    G  G  L+ +P      + 
Sbjct: 76  VALQLGGNDPVKMAEAARIGEAYGYDEINMNVGCPSDRVQSGTFGACLMQEPALVADCIA 135

Query: 490 TLVDNLSIPVTCKIRI 537
            +   + IPVT K RI
Sbjct: 136 AMKAAVEIPVTVKCRI 151


>UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4;
           Neisseria|Rep: tRNA-dihydrouridine synthase C -
           Neisseria meningitidis serogroup A
          Length = 333

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 42/152 (27%), Positives = 67/152 (44%), Gaps = 3/152 (1%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQ-T 267
           + +IILAPM  +    MR L  + G      +E +  +F+R     +     + YV +  
Sbjct: 12  KTRIILAPMQGLVDDVMRDLLTRIGG----YDECVS-EFVRITHTVHSRATWLKYVPEIA 66

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
           +G   F          V  LG+  +  A    + V      ID+N GCP     +   G 
Sbjct: 67  NGNKTF----SGTPCTVQLLGSDADNMAANALEAVRFGADKIDLNFGCPAPTVNRHKGGA 122

Query: 448 ALLSKPDKAYQILKTLVDNL--SIPVTCKIRI 537
            LL +P+  + I+KTL + L   IP+T K+R+
Sbjct: 123 ILLKEPELIFHIVKTLRERLPAHIPLTAKMRL 154


>UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5;
           Bacteroidetes|Rep: Putative uncharacterized protein -
           Polaribacter irgensii 23-P
          Length = 317

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
 Frame = +1

Query: 310 KVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQIL 486
           +V+ Q+ T D    L V+K V       ++ N+GCP     K GMG  L+S  +K   IL
Sbjct: 62  EVIPQIITNDAEEFLFVSKYVRALGYKELNWNLGCPYPMVTKRGMGSGLISDAEKINSIL 121

Query: 487 KTLVDNLSIPVTCKIRI-LKTPEATLELVNKLITYQFQS 600
             + +   I V+ K+R+  + PE  L ++  L TY  ++
Sbjct: 122 HKVHNESDILVSMKMRMGYENPEEILGVLPILDTYPLKN 160


>UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putative;
           n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 4,
           putative - Trypanosoma brucei
          Length = 419

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 4/149 (2%)
 Frame = +1

Query: 103 ILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIV 282
           I APMVR      R L   +G DI YT  ++   F  S+              Q + +I 
Sbjct: 62  IQAPMVRCSRPAFRKLCRLWGTDISYTHMIMADSFACSEA-----------ARQAEFSIY 110

Query: 283 FRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
                  + +++ QL +     A   A +V     AID+N GCP+   +  G+G ALL  
Sbjct: 111 -----SGETRLITQLASSSGPTAATAAAIVAPWCDAIDLNCGCPQRRVMADGLGAALLRN 165

Query: 463 P----DKAYQILKTLVDNLSIPVTCKIRI 537
           P    D    +   L   + +P   K+R+
Sbjct: 166 PEVVADTVRCVRNALEGGVELPCVVKMRV 194


>UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein;
           n=1; Lentisphaera araneosa HTCC2155|Rep: Dihydrouridine
           synthase family protein - Lentisphaera araneosa HTCC2155
          Length = 334

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
 Frame = +1

Query: 295 EEEKKKVVLQL-GTCDEARALKVAKLVEHDVA-AIDINMGCPKEFSIKGGMGVALLSKPD 468
           +E+  K+V Q+ G   +  +  ++K V+ +V   +DINMGCP    +K G   AL++ P+
Sbjct: 76  KEKNIKIVAQVWGKNPDKFSEAISKYVDPEVFDGVDINMGCPVAKIVKQGGCSALINTPE 135

Query: 469 KAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLI 582
            A +++        +PV+ K R   T   T E +  L+
Sbjct: 136 IAKELVLAAKAATKLPVSVKTRTGITAHKTEEWMTHLL 173


>UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein;
           n=1; Bdellovibrio bacteriovorus|Rep: Dihydrouridine
           synthase family protein - Bdellovibrio bacteriovorus
          Length = 323

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           LG   E  AL   + V+     +D+N GCP +   +   G +LL   D+ + I+ T+   
Sbjct: 70  LGGQAEPLALNAQRAVKLGALGVDLNFGCPAKTVNRHDGGASLLKSCDRVFNIVDTVRKA 129

Query: 505 L--SIPVTCKIRI-LKTPEATLEL 567
           +   +PVT KIR+    P   LE+
Sbjct: 130 VPADVPVTAKIRLGFDDPTKCLEI 153


>UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase;
           n=1; Hyphomonas neptunium ATCC 15444|Rep: Putative
           tRNA-dihydrouridine synthase - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 345

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 4/156 (2%)
 Frame = +1

Query: 82  MNYEN-KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           +N+E  ++ LAPM      PMR  A+ +GA  V +E ++  + L   R            
Sbjct: 16  INFEAPRVWLAPMSGATDAPMRRQAVHFGAPAVVSE-MVAGEMLAKAR------------ 62

Query: 259 DQTDGTIVFRTCEEEKKKV-VLQLGTCDEARALKVAKLV-EHDVAAIDINMGCPKEFSIK 432
                 +V RTC  E     ++QL        L  A L+ E  V  IDINMGCP +    
Sbjct: 63  ----ADVVRRTCRHEGAGYWIVQLAARRPEDMLAGAVLMAEAGVDVIDINMGCPSKQVTG 118

Query: 433 GGMGVALLSKPDKAYQILKTLVDNLS-IPVTCKIRI 537
           G  G AL+     A +I+   +   +  PVT K+R+
Sbjct: 119 GQSGSALMRDLPLAGEIIDAALQGAAGRPVTLKMRL 154


>UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5;
           Bacteria|Rep: Transcriptional regulator - Anabaena sp.
           (strain PCC 7120)
          Length = 349

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = +1

Query: 364 KLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLS-IPVTCKIRI 537
           +L  +++A +D+NMGCP     +  +G  LL  P K  QIL+ L   ++  P+T K+R+
Sbjct: 101 ELCGYNIAGVDLNMGCPAPRIYRKNVGGGLLLSPAKVEQILEELRQAVNDRPLTVKMRV 159


>UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2;
           Bacteria|Rep: Putative uncharacterized protein -
           Plesiocystis pacifica SIR-1
          Length = 362

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
 Frame = +1

Query: 313 VVLQLGTCD-EARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILK 489
           + LQLG  D EA A       E     ++IN+GCP +    G  GV L+  P +    + 
Sbjct: 77  LALQLGGDDPEALAACARIAAELGYDEVNINVGCPSDRVQSGNFGVCLMKDPARVRDCVV 136

Query: 490 TLVDNLSIPVTCKIRI 537
            + + + +PVT K RI
Sbjct: 137 AMREAVELPVTVKHRI 152


>UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1;
           Trichomonas vaginalis G3|Rep: Dihydrouridine synthase,
           putative - Trichomonas vaginalis G3
          Length = 318

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 35/153 (22%), Positives = 64/153 (41%), Gaps = 4/153 (2%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           E  I LAPM  I  L  R+L   +G  + +T  L   ++ +     N   NT        
Sbjct: 17  EKPICLAPMAEISDLSWRMLIRNHGVKVCWTGMLNAHQWSQGSGYQNKFFNT-------- 68

Query: 271 GTIVFRTCEEEKKKVVLQLGTC-DEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
                  C E+   +    G+  D+   +  AK +      +D+N+GC ++ + +   G 
Sbjct: 69  -------CPEDHPLIAQIAGSNEDQDLIVAAAKDLAKYADGVDVNLGCTQKIASRSEYGY 121

Query: 448 ALL---SKPDKAYQILKTLVDNLSIPVTCKIRI 537
            ++    K +K  ++ + L   ++ P+  KIRI
Sbjct: 122 FMVDNCQKREKTLELFRRLCKEVNCPICAKIRI 154


>UniRef50_Q6A959 Cluster: TIM-barrel enzyme, NifR3 family; n=1;
           Propionibacterium acnes|Rep: TIM-barrel enzyme, NifR3
           family - Propionibacterium acnes
          Length = 411

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           ++ +  ++LAPM  +     R L  + GA + Y  E+I  + L     + D         
Sbjct: 46  VSVDTPVVLAPMAGVTNAAFRQLCAEQGAGL-YVCEMITSRGLV----YGD--------H 92

Query: 262 QTDGTIVFRTCEEEKKKVVLQL--GTCDEARALKVAKLVEHDVAAIDINMGCP-KEFSIK 432
           +T G + F  CE+ +   +  +  G   EA ++   K   + V  +D+N GCP  + + K
Sbjct: 93  KTHGMLAFAECEDVRSVQLYGVDPGMVGEATSILCEK---YGVNHVDLNFGCPVPKVTRK 149

Query: 433 GGMGVALLSKPDKAYQILKTLV---DNLSIPVTCKIRILKTPE 552
           GG GV L  K D+   ++   V   D   +PVT K RI   PE
Sbjct: 150 GGGGV-LPWKLDRFAAVVSAAVQAGDAHGVPVTVKTRIGIDPE 191


>UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1;
           Chromohalobacter salexigens DSM 3043|Rep: Dihydrouridine
           synthase, DuS - Chromohalobacter salexigens (strain DSM
           3043 / ATCC BAA-138 / NCIMB13768)
          Length = 340

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 4/143 (2%)
 Frame = +1

Query: 121 RIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVFRTCEE 300
           RIG  PM  +      +++  +  +DW      R  +  L    ++              
Sbjct: 8   RIGLAPMEGVIDVVTRELLSADGALDWTVTEFVRVVDTRLPARVFLRHCPELETAACATA 67

Query: 301 EKKKVVLQL-GTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAY 477
               V LQL G+  EA A    +        +D+N GCP +   +   G +LL +P++ +
Sbjct: 68  SGTPVHLQLLGSDPEALAANAVRAQALGARQVDLNFGCPAKTVNRHDGGASLLRQPERVH 127

Query: 478 QILKTLVDNLS---IPVTCKIRI 537
            +++ + + L+   I VT KIR+
Sbjct: 128 TVVRAVAEALAPLGIAVTAKIRL 150


>UniRef50_A5KKR3 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus torques ATCC 27756|Rep: Putative
           uncharacterized protein - Ruminococcus torques ATCC
           27756
          Length = 211

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 20/71 (28%), Positives = 34/71 (47%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           L  C E       KL ++    I++N+GCP +  +  G G   L+ P++    L+ +  N
Sbjct: 66  LTNCAEDFVQTAKKLEQYGYKEINLNVGCPSKTVVTKGRGAGFLAFPERLDLFLEEVFQN 125

Query: 505 LSIPVTCKIRI 537
             I ++ K RI
Sbjct: 126 CPIDISVKTRI 136


>UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 392

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 26/65 (40%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
 Frame = +1

Query: 355 KVAKLVEHDVAAIDINMGCP--KEFSIKGGMGVALLSKPDKAYQILKTLVD--NLSIPVT 522
           K+A  + +D   +DINMGCP  K  S K   G AL++ P  A +I+K   +  N   PV+
Sbjct: 87  KIANELGYD--GVDINMGCPSRKVLSPKQASGAALITNPSLAKEIVKITKEALNFEKPVS 144

Query: 523 CKIRI 537
            K RI
Sbjct: 145 VKTRI 149


>UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase;
           n=5; Moraxellaceae|Rep: Possible tRNA-dihydrouridine
           synthase - Psychrobacter arcticum
          Length = 350

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           LG+  +  A   A   E    AIDIN GCP +       G  LL +P+  Y I+  +   
Sbjct: 105 LGSEAQLMAENAAHACELGAPAIDINFGCPAKTVNSHRGGSVLLDEPEVMYDIISAVRQA 164

Query: 505 L--SIPVTCKIRILKTPEATLE 564
           +  +IPV+ KIR+  T  + ++
Sbjct: 165 VPANIPVSAKIRLGYTDTSRMD 186


>UniRef50_Q056Y8 Cluster: TRNA-dihydrouridine synthase A; n=1;
           Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
           TRNA-dihydrouridine synthase A - Buchnera aphidicola
           subsp. Cinara cedri
          Length = 348

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 15/49 (30%), Positives = 30/49 (61%)
 Frame = +1

Query: 391 IDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           I++N+GCP + +  G  G+ L++ P   Y ++K +   + I ++ KIR+
Sbjct: 112 INLNIGCPSKKAKSGNFGIYLMNNPILVYNLIKAIYLTVPIQISIKIRL 160


>UniRef50_Q17M24 Cluster: tRNA-dihydrouridine synthase; n=1; Aedes
           aegypti|Rep: tRNA-dihydrouridine synthase - Aedes
           aegypti (Yellowfever mosquito)
          Length = 578

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVD 261
           +N+++K+ L+P+  +G LP R +  +YG DI   E       +    +   +        
Sbjct: 225 INFKDKLYLSPLTTVGNLPFRRICKEYGVDITCGEMACSVPIINGMMQEWALTKR----H 280

Query: 262 QTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGG 438
            ++     + C   +K V         + A +V  + EH DV  +D+N+GCP +     G
Sbjct: 281 PSEDLFGVQICGHNQKLV---------SYATQV--IAEHADVDFVDLNLGCPIDLIFNQG 329

Query: 439 MGVALLSK 462
            G ALL +
Sbjct: 330 GGSALLRR 337


>UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2;
           Candidatus Pelagibacter ubique|Rep: Putative
           uncharacterized protein - Pelagibacter ubique
          Length = 330

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
 Frame = +1

Query: 304 KKKVVLQLGTCDE---ARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKA 474
           +K + LQ+G       A A KV +   +D   I++N+GCP +   K   G  L+ +P+  
Sbjct: 56  EKPIALQIGGSSPTLLAEATKVGEDFGYD--EINLNLGCPSKKVEKNKFGACLMKEPNLV 113

Query: 475 YQILKTLVDNLSIPVTCKIRI 537
              L  +     +PVT K RI
Sbjct: 114 ADCLSKMQSVTKLPVTIKTRI 134


>UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225;
           n=3; Borrelia burgdorferi group|Rep: Putative
           uncharacterized protein BB0225 - Borrelia burgdorferi
           (Lyme disease spirochete)
          Length = 335

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
 Frame = +1

Query: 313 VVLQLGTCDEARALKVAKLVEH--DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQIL 486
           + +Q+ T  +  ALK  +++E   +    ++N+GCP         G  L+   ++  +IL
Sbjct: 61  IAIQIATNSKNDALKAIQILEKHFNFDEYNLNVGCPSLKIQNANCGACLMGNANQVGEIL 120

Query: 487 KTLVDNLSIPVTCKIRI 537
           KT+ +N + P++ K R+
Sbjct: 121 KTMKENTNKPISIKHRL 137


>UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1;
           Oceanobacter sp. RED65|Rep: Putative uncharacterized
           protein - Oceanobacter sp. RED65
          Length = 321

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 46/152 (30%), Positives = 69/152 (45%), Gaps = 5/152 (3%)
 Frame = +1

Query: 97  KIILAPMVRIGTLPMRLLALKYGA-DIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD- 270
           ++ LAPM  +  + MR L  + G  D   TE L     L  +R F  I    D+  +T  
Sbjct: 2   QLSLAPMEGLVDVHMRTLLTRGGYFDYCVTEFLRVTTQLLPERSFRRICPESDHQWKTPA 61

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVA 450
           GT V           +  LG+   A A    +  E     ++IN GCP  F + G  G A
Sbjct: 62  GTPVH----------LQLLGSDPVAMAENACRAAELGAPVVNINFGCPSRF-VNGRCGGA 110

Query: 451 -LLSKPDKAYQILKTLVDNL--SIPVTCKIRI 537
            LL  PD+ + IL+++   L   +P+T K+R+
Sbjct: 111 YLLQFPDQIHTILESVRKALPEHVPLTAKMRL 142


>UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5;
           Alteromonadales|Rep: TRNA-dihydrouridine synthase C -
           Pseudoalteromonas haloplanktis (strain TAC 125)
          Length = 326

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           LG    A A    K +      ID+N GCP +   K   G  LL  P+  Y+I+K + D 
Sbjct: 70  LGQVAGALAENAVKAISLGSHGIDLNFGCPAKTVNKSKGGAVLLKDPEHMYEIIKAVRDA 129

Query: 505 LSI--PVTCKIRI 537
           +     V+ KIR+
Sbjct: 130 VDSKHQVSAKIRL 142


>UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3;
           Fusobacterium nucleatum|Rep: Nitrogen regulation protein
           NIFR3 - Fusobacterium nucleatum subsp. nucleatum
          Length = 307

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 4/72 (5%)
 Frame = +1

Query: 364 KLVEH-DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTL--VDNLSIPVTCKIR 534
           K +E+  V  I++N GCP +  +  G G AL+ +P+K  +IL  +  V N    ++ KIR
Sbjct: 74  KYIENLGVKHINLNCGCPMKKIVNCGYGAALVKEPEKIKKILSEIKSVLNNDTKLSVKIR 133

Query: 535 I-LKTPEATLEL 567
           I  K PE  +++
Sbjct: 134 IGYKEPENYIQI 145


>UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7;
           Bacteria|Rep: TIM-barrel protein, yjbN family - Coxiella
           burnetii
          Length = 353

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
 Frame = +1

Query: 301 EKKKVVLQLGTCDEARALKVAKLVEHD-VAAIDINMGCPKEFSIKGGMGVALLSKPDKAY 477
           E+  + LQ+G  D       A+L E      I++N+GCP    I G  G  LL + +   
Sbjct: 81  EEHPLALQVGGSDPQSLALCARLAEEKGFDEINLNVGCPSGRVIAGRFGACLLKEAELVA 140

Query: 478 QILKTLVDNLSIPVTCKIR 534
             +  +   ++IPV+ K R
Sbjct: 141 DCVAAMSAEVNIPVSVKTR 159


>UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase;
           n=41; Bacilli|Rep: Probable tRNA-dihydrouridine synthase
           - Staphylococcus aureus (strain COL)
          Length = 328

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +1

Query: 295 EEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKA 474
           E+E+  V    G   E       +L +     ID+NMGCP     K G G  L+ +PD A
Sbjct: 67  EDEQPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVA 126

Query: 475 YQILKTLVDNLSIPVTCKIRI 537
            +I++       +PV+ K R+
Sbjct: 127 AEIIQATKAG-GLPVSVKTRL 146


>UniRef50_Q7R3K2 Cluster: GLP_158_4738_3071; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_158_4738_3071 - Giardia lamblia ATCC
           50803
          Length = 555

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 3/151 (1%)
 Frame = +1

Query: 91  ENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTD 270
           +  ++LAPM  +GT+P R L + YG +I   E +     L    +  ++     + D+  
Sbjct: 173 QKPLMLAPMCTVGTIPFRRLCIHYGCEITLCEMVFARDILHGDAQ--ELRKIKRHPDEKC 230

Query: 271 GTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVA 450
             I      +E  ++V  +  C                  ID+N  CP++ + K   G A
Sbjct: 231 FGIQLAGRGQELMEIVNFISQCCSC-------------DFIDLNAACPQDIATKKCCGAA 277

Query: 451 LLSKPDKAYQILKTLV---DNLSIPVTCKIR 534
           L +   K    +  +V   ++  +PV  KIR
Sbjct: 278 LAANLKKLVSSVDCMVRGGEHYGVPVFLKIR 308


>UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 641

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
 Frame = +1

Query: 358 VAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTL-VDNLSIPVTCKIR 534
           +++L+ H +  +D+N GCP +   K G G ALL    K  ++++ +   +  +P+T KIR
Sbjct: 328 LSQLLPH-LRLVDLNCGCPVDAVFKSGSGSALLDSHSKLERMIRGMNAVSGEVPITAKIR 386

Query: 535 I 537
           +
Sbjct: 387 M 387


>UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase C -
           Ralstonia solanacearum (Pseudomonas solanacearum)
          Length = 326

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +1

Query: 313 VVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKT 492
           V+  LG+  E  A   A+        ID+N GCP +   + G G  LL+ P+  ++I+ T
Sbjct: 67  VIQLLGSDPEWLARNAAQAATVSPHGIDLNFGCPAKVVNRHGGGAMLLATPELLHRIVST 126

Query: 493 L--VDNLSIPVTCKIRI 537
           +       I VT K+R+
Sbjct: 127 VRAAVPARIAVTAKMRL 143


>UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3;
           Proteobacteria|Rep: Dihydrouridine synthase, DuS -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 344

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTL--V 498
           LG+     A   A+L     A ID+N GCP     + G G +LL +P+    I+  +   
Sbjct: 76  LGSDPACMAENAARLATLGPAGIDLNFGCPAAVVNRHGGGASLLKEPETLLAIVSAVRRA 135

Query: 499 DNLSIPVTCKIRI 537
               +PV+ K+R+
Sbjct: 136 VPAGMPVSAKMRL 148


>UniRef50_Q47741 Cluster: Dihydroorotate dehydrogenase B, catalytic
           subunit; n=104; Bacteria|Rep: Dihydroorotate
           dehydrogenase B, catalytic subunit - Enterococcus
           faecalis (Streptococcus faecalis)
          Length = 312

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 21/69 (30%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
 Frame = +1

Query: 328 GTCDEARALKVAKLVEH-DVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           G C+E      AK+ +  +V AI++N+ CP   ++K G G+A  + P+ A+Q+ + +   
Sbjct: 105 GACEEDYVAVCAKIGQAPNVKAIELNISCP---NVKHG-GIAFGTDPEVAFQLTQAVKKV 160

Query: 505 LSIPVTCKI 531
            S+P+  K+
Sbjct: 161 ASVPIYVKL 169


>UniRef50_O53835 Cluster: Probable tRNA-dihydrouridine synthase;
           n=35; Actinobacteria (class)|Rep: Probable
           tRNA-dihydrouridine synthase - Mycobacterium
           tuberculosis
          Length = 389

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 5/93 (5%)
 Frame = +1

Query: 274 TIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIKGGMGV 447
           T+   T   ++    LQL T D       A+++  +  A  ID+N GCP     K G G 
Sbjct: 73  TMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGA 132

Query: 448 ALLSKPDKAYQILKTLV---DNLSIPVTCKIRI 537
           AL  K     QI+   V   +   IPVT K RI
Sbjct: 133 ALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRI 165


>UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1;
           Desulfotalea psychrophila|Rep: Putative uncharacterized
           protein - Desulfotalea psychrophila
          Length = 354

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 16/49 (32%), Positives = 27/49 (55%)
 Frame = +1

Query: 391 IDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           +DIN+GCP     +GG G AL    D+   I+ +   +  + ++ KIR+
Sbjct: 127 VDINLGCPAPSVRRGGAGAALAEDWDRVRDIVSSARRHTDLTLSAKIRV 175


>UniRef50_Q1F0W8 Cluster: Dihydroorotate dehydrogenase 1; n=1;
           Clostridium oremlandii OhILAs|Rep: Dihydroorotate
           dehydrogenase 1 - Clostridium oremlandii OhILAs
          Length = 372

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 19/69 (27%), Positives = 34/69 (49%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           LG      A    K+ +    A+++ + CP    ++G     ++S+P K Y+  K +VD 
Sbjct: 98  LGHTSSEIAYIAQKVEQFGADAVELGVSCPHGEGLEG-----VISEPSKLYEFTKAVVDR 152

Query: 505 LSIPVTCKI 531
           + IPV  K+
Sbjct: 153 IKIPVMVKL 161


>UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 307

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
 Frame = +1

Query: 334 CDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNL-S 510
           C E  A    ++   D+  IDINMGCP       G G  L+   DKA ++ + +V     
Sbjct: 62  CMEEAAAIAGEVSGADI--IDINMGCPVPKVANSGDGSGLMRDVDKAVRVAEAVVRGAGE 119

Query: 511 IPVTCKIRI 537
            PVT K R+
Sbjct: 120 RPVTVKFRL 128


>UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2;
           Gammaproteobacteria|Rep: NifR3/Smm1 family protein -
           Reinekea sp. MED297
          Length = 314

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 17/61 (27%), Positives = 32/61 (52%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDN 504
           LG+  +A A    + +E     +D+N GCP +       G  LL++P+  Y +++++ D 
Sbjct: 70  LGSHPQALAENALRAIELGSHGLDLNFGCPSKTVNASKGGAVLLTEPESIYAVVRSVRDA 129

Query: 505 L 507
           L
Sbjct: 130 L 130


>UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2;
           unclassified Gammaproteobacteria|Rep:
           TRNA-dihydrouridine synthase C - Congregibacter
           litoralis KT71
          Length = 328

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
 Frame = +1

Query: 292 CEEEKKKVVLQ-LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPD 468
           C      V LQ LG      A   ++  E     +D+N GCP +   +   G  +L +P+
Sbjct: 64  CTSSGVPVYLQILGGDPSVVAENASRAAELGAPGVDLNFGCPAKTVNRSDGGSIILREPE 123

Query: 469 KAYQILKTLVDNL--SIPVTCKIRI 537
           + ++I+      L  S+P++ KIR+
Sbjct: 124 RVHRIVAATRQALPPSVPLSVKIRL 148


>UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 278

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 16/58 (27%), Positives = 29/58 (50%)
 Frame = +1

Query: 316 VLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILK 489
           + Q G C      +   L+   V  +DIN GCP+ ++    +G AL+ K +   +++K
Sbjct: 38  IAQFGVCSPLEISRSTTLLAPYVNGVDINCGCPQSWACACSIGAALMHKRELVAEMVK 95


>UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14784,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 505

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
 Frame = +1

Query: 115 MVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKR-RFNDILNTVDYVDQTDGTIVFRT 291
           MV    L  RLL+ ++GA + YT       F+R    R +++ N V              
Sbjct: 1   MVDQSELAWRLLSRRHGAQLCYTPMFHAQVFVRDANYRRDNLYNEV-------------- 46

Query: 292 CEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVAL 453
           CEE++  ++ Q    D    ++ A L +    AID+N+GCP+  + +G  G  L
Sbjct: 47  CEEDRP-LITQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFL 99


>UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2;
           Betaproteobacteria|Rep: Dihydrouridine synthase, DuS -
           Dechloromonas aromatica (strain RCB)
          Length = 319

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
 Frame = +1

Query: 325 LGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTL--V 498
           LG+     A    +LV  + A +D+N GCP     +   G ALL +P+   +I   +  V
Sbjct: 71  LGSDPHFMAENARRLVALNPAGVDLNFGCPAPTVFRHRGGSALLGEPELLNEITSAVRSV 130

Query: 499 DNLSIPVTCKIRI 537
               IP T K+R+
Sbjct: 131 VPAHIPFTAKMRL 143


>UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase;
           n=1; Aquifex aeolicus|Rep: Probable tRNA-dihydrouridine
           synthase - Aquifex aeolicus
          Length = 316

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 41/156 (26%), Positives = 68/156 (43%), Gaps = 4/156 (2%)
 Frame = +1

Query: 82  MNYEN-KIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYV 258
           MN++  ++ILAPM        R L  + GAD  YTE +     LR     N I   + Y 
Sbjct: 1   MNFKKGEVILAPMASYTHSAFRRLCRRLGADRTYTELISAVGVLR-----NGIPMKLAYF 55

Query: 259 DQTDGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGG 438
            + +  I  +      +++           ++ +AK ++ D   IDIN GC     ++  
Sbjct: 56  TEEERPIHIQVFGSNPEEIA--------QASVVIAKELKPDF--IDINFGCSVPKVLRNK 105

Query: 439 MGVALLSKPDKAYQILKTLVDNL---SIPVTCKIRI 537
               +L  P    +++K  V+ L    IPV+ KIR+
Sbjct: 106 AAGYMLQCPPLMGEVVKETVEALKPYGIPVSAKIRL 141


>UniRef50_O51679 Cluster: Histidine phosphokinase/phophatase,
           putative; n=3; Borrelia burgdorferi group|Rep: Histidine
           phosphokinase/phophatase, putative - Borrelia
           burgdorferi (Lyme disease spirochete)
          Length = 335

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 3/51 (5%)
 Frame = +1

Query: 391 IDINMGCPKEFSIKGGMGVALLSKPDKAYQIL---KTLVDNLSIPVTCKIR 534
           IDINMGCPK   IK G+  AL++    A +I+   K      ++P++ K R
Sbjct: 107 IDINMGCPKSKIIKKGVCSALINNKSLAKEIILASKEACARFNLPLSVKTR 157


>UniRef50_A5EXU5 Cluster: TRNA-dihydrouridine synthase A; n=1;
           Dichelobacter nodosus VCS1703A|Rep: TRNA-dihydrouridine
           synthase A - Dichelobacter nodosus (strain VCS1703A)
          Length = 335

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
 Frame = +1

Query: 265 TDGTIVFRTCE-----EEKKKVVLQLGTC--DE-ARALKVAKLVEHDVAAIDINMGCPKE 420
           T G I+F   +     +  +   LQLG    DE ARA  +A+   +  A +++N+GCP +
Sbjct: 41  TTGAILFGDAQRYLTHQNDEPCALQLGGSNPDELARATAIAQ--SYHYAEMNLNVGCPSD 98

Query: 421 FSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
                 +G  L+  P    Q L  +     +PV+ K R+
Sbjct: 99  RVQNNQIGACLMKSPRLVAQCLTAMQKESDVPVSIKHRL 137


>UniRef50_Q9RDC6 Cluster: Putative uncharacterized protein SCO2497;
           n=5; Bacteria|Rep: Putative uncharacterized protein
           SCO2497 - Streptomyces coelicolor
          Length = 406

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 40/149 (26%), Positives = 63/149 (42%), Gaps = 4/149 (2%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKY-GADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           ++LAPM  I   P R L  ++ G   ++  E+I  + L            V+  ++T   
Sbjct: 27  VVLAPMAGITNAPFRTLCREFSGGKGLFVSEMITTRAL------------VERNEKTMQL 74

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAA--IDINMGCPKEFSIKGGMGVA 450
           I F   E  +    +QL   D     K  +++  +  A  ID+N GCP     + G G A
Sbjct: 75  IHFDATETPRS---IQLYGVDPVTVGKAVRMIAEEGLADHIDLNFGCPVPKVTRKGGGSA 131

Query: 451 LLSKPDKAYQILKTLVDNL-SIPVTCKIR 534
           L  K      I++  V     +PVT K+R
Sbjct: 132 LPYKRHLLRAIVREAVTGAGDLPVTMKMR 160


>UniRef50_Q97DM0 Cluster: Predicted TIM-barrel enzyme, nifR3 family;
           n=17; Clostridiales|Rep: Predicted TIM-barrel enzyme,
           nifR3 family - Clostridium acetobutylicum
          Length = 311

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = +1

Query: 364 KLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILK 543
           KL+    + +++N+GCP    +  G G   L K  +  + L+ +       ++ K RI K
Sbjct: 79  KLMNLGYSEVNLNLGCPSGTVVSKGRGAGFLKKRQELDEFLEKIFSKSPAKISIKTRIGK 138

Query: 544 -TPEATLELVNKLITYQFQ 597
            +P+   EL+     Y  +
Sbjct: 139 DSPDEFYELIKIFNKYPLE 157


>UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2;
           Methylobacterium extorquens PA1|Rep: Dihydrouridine
           synthase, DuS - Methylobacterium extorquens PA1
          Length = 354

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 20/67 (29%), Positives = 33/67 (49%)
 Frame = +1

Query: 337 DEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIP 516
           D A A ++A   +   A I++N+GCP +    G  G  L+ +P      +  L   + +P
Sbjct: 95  DLAAAARIA--ADFGYAEINLNVGCPSDRVQDGRFGACLMREPGLVGACVAALKAAVPVP 152

Query: 517 VTCKIRI 537
           VT K R+
Sbjct: 153 VTVKCRL 159


>UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4;
           Desulfovibrionaceae|Rep: Dihydrouridine synthase, DuS -
           Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
          Length = 449

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 33/132 (25%), Positives = 54/132 (40%), Gaps = 1/132 (0%)
 Frame = +1

Query: 106 LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVF 285
           LAP+     L  RLL  K GA +  TE                +++    +  + GT   
Sbjct: 36  LAPLAGYSDLSFRLLCRKAGAAVCCTE----------------MVSAKGLIYYSPGTRDL 79

Query: 286 RTCEEEKKKVVLQLGTCDEARALKVAK-LVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
                E   +V+QL  CD    ++  + L+E      D+NMGC     +K G G A+L  
Sbjct: 80  LATTPEDAPLVVQLFGCDPDIMVRAMEPLLEQGFRWFDLNMGCSVPKVVKTGCGAAMLRD 139

Query: 463 PDKAYQILKTLV 498
             +A  + + ++
Sbjct: 140 VPQALAVARAML 151


>UniRef50_Q8G660 Cluster: Dihydroorotate dehydrogenase; n=4;
           Bifidobacterium|Rep: Dihydroorotate dehydrogenase -
           Bifidobacterium longum
          Length = 323

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +1

Query: 328 GTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNL 507
           G CD+  A  V KL + D   ++IN+ CP   +  GGM V   + P      L  L+D L
Sbjct: 122 GHCDDDYAAVVEKLADSDADMLEINVSCPNVSA--GGMSVG--TDP----VALANLMDRL 173

Query: 508 SIPVTCKIRILK-TPEAT 558
             P+T K  I+K TP  T
Sbjct: 174 R-PMTDKPMIVKLTPNVT 190


>UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1;
           Caminibacter mediatlanticus TB-2|Rep:
           tRNA-dihydrouridine synthase B - Caminibacter
           mediatlanticus TB-2
          Length = 311

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 31/148 (20%), Positives = 68/148 (45%), Gaps = 4/148 (2%)
 Frame = +1

Query: 106 LAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVF 285
           LAP+     LP R +  ++G D+ ++E +I+              N + + ++    ++ 
Sbjct: 15  LAPLAGYTDLPFRSVVKEFGCDMTFSE-MIN-------------ANAIAFNNEKTKKMMQ 60

Query: 286 RTCEEEKKKVVLQLGTCDEARALKVAKLVEHD--VAAIDINMGCPKEFSIKGGMGVALL- 456
           ++ +E      +Q+   +   A+K  +++     +  IDIN+GCP   + + G G  LL 
Sbjct: 61  KSSKETP--YFIQIAANNVENAIKAVEIINEIPWIDGIDINLGCPVNKARRSGYGGVLLK 118

Query: 457 -SKPDKAYQILKTLVDNLSIPVTCKIRI 537
               +K  +I+  ++      V+ K+R+
Sbjct: 119 DENKEKLKEIVSAIIKTSKKIVSAKMRL 146


>UniRef50_Q7SGX4 Cluster: Putative uncharacterized protein
           NCU03195.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU03195.1 - Neurospora crassa
          Length = 341

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 15/49 (30%), Positives = 25/49 (51%)
 Frame = +1

Query: 316 VLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
           V+Q G  D     + + LV      +D+N GCP+ ++    +G AL+ K
Sbjct: 35  VVQFGANDPQELARASTLVAPYAGGVDLNCGCPQSWACAETLGAALMEK 83


>UniRef50_A6RVN2 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 1174

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 16/36 (44%), Positives = 23/36 (63%)
 Frame = +1

Query: 478 QILKTLVDNLSIPVTCKIRILKTPEATLELVNKLIT 585
           +++ TL   L +PVT KIRIL T E TL+    +I+
Sbjct: 783 ELINTLHKELDVPVTAKIRILDTREKTLDYAKMVIS 818


>UniRef50_A4RL93 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 313

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 15/58 (25%), Positives = 29/58 (50%)
 Frame = +1

Query: 289 TCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSK 462
           T  + +   ++Q G        + + LV   VA +D+N GCP+ ++    +G AL+ +
Sbjct: 34  TTPQPQPPTIVQFGANVPVELARASSLVAPFVAGVDLNCGCPQSWACAETLGAALMER 91


>UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep: Dihydrouridine
           synthase, DuS - Desulfuromonas acetoxidans DSM 684
          Length = 320

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 40/159 (25%), Positives = 66/159 (41%), Gaps = 2/159 (1%)
 Frame = +1

Query: 100 IILAPMVRIGTLPMRLLALKYGA-DIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGT 276
           ++LAPM  +    MR +    G  D+V+TE +      R +   ND    +  VD     
Sbjct: 13  LMLAPMQGLTNRAMRAVQCDIGQPDVVFTEFVRVSHVARQRITPNDRREILAGVDDVP-- 70

Query: 277 IVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALL 456
                       VV  +G   E+ A     + +   A +++NMGCP   +  G  G A+L
Sbjct: 71  -----------LVVQLIGHRSESLAEAAQIVADLGGAHVNLNMGCPFGRTTTGKTGGAML 119

Query: 457 SKPDKAYQILKTLVDNLSIPVTCKIRI-LKTPEATLELV 570
            +P+K    L+ +       V+ K+R     PE   +L+
Sbjct: 120 QEPEKIGDCLRAIRAAFHGSVSVKVRAGYDDPEQIFDLL 158


>UniRef50_A7AAN4 Cluster: Putative uncharacterized protein; n=2;
           Bacteroidales|Rep: Putative uncharacterized protein -
           Parabacteroides merdae ATCC 43184
          Length = 320

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 15/48 (31%), Positives = 26/48 (54%)
 Frame = +1

Query: 394 DINMGCPKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRI 537
           DIN+GCP     +   G  +L  PD+   +L+T+ +   I  + K+R+
Sbjct: 92  DINLGCPFPMQARQHRGAGILPYPDEVKVLLETIFEFPEIQFSVKLRL 139


>UniRef50_A1RZC9 Cluster: Dihydroorotate dehydrogenase family
           protein; n=1; Thermofilum pendens Hrk 5|Rep:
           Dihydroorotate dehydrogenase family protein -
           Thermofilum pendens (strain Hrk 5)
          Length = 299

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 20/61 (32%), Positives = 33/61 (54%)
 Frame = +1

Query: 313 VVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKT 492
           V+  +G      AL++A+ +E    A+++N  CP    +KG +G  L+S PD  Y I+  
Sbjct: 96  VIASIGASTPDEALRIAEALE-GFDALELNASCPH---VKG-LGADLMSDPDAVYGIVSA 150

Query: 493 L 495
           L
Sbjct: 151 L 151


>UniRef50_Q979G6 Cluster: Dihydroorotate dehydrogenase; n=4;
           Thermoplasmatales|Rep: Dihydroorotate dehydrogenase -
           Thermoplasma volcanium
          Length = 301

 Score = 34.7 bits (76), Expect = 2.3
 Identities = 21/80 (26%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
 Frame = +1

Query: 295 EEEKKKVVLQLGTCDEARALKVA-KLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDK 471
           +E K+ ++  +   +     K++ K+ E+ V AI++N+ CP    +KG  G+ + S PD 
Sbjct: 89  KEAKRPIIGSVFAYNAEEFTKLSVKMEEYGVDAIELNLSCPH---VKG-FGLEVGSDPDL 144

Query: 472 AYQILKTLVDNLSIPVTCKI 531
              I+  +   + +PV  K+
Sbjct: 145 VEDIVNEIKSKVKVPVFAKL 164


>UniRef50_UPI0000F1F64B Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 1509

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 19/67 (28%), Positives = 32/67 (47%)
 Frame = +1

Query: 160 YGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVFRTCEEEKKKVVLQLGTCD 339
           +  ++ Y +E + W  L  K  FN+ +NT+ +VD+T    +     E+  KV   +    
Sbjct: 204 FTCEVNYADEEVQWT-LNDKPLFNNEVNTITHVDKTHTLSLKNLAPEDGGKVSFSIRDVK 262

Query: 340 EARALKV 360
           E   LKV
Sbjct: 263 ETVCLKV 269


>UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2;
           Proteobacteria|Rep: TRNA-dihydrouridine synthase -
           Ralstonia solanacearum UW551
          Length = 369

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +1

Query: 292 CEEEKKKVVLQLGTCDEA-RALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPD 468
           C      +V+QL   D    A   A+        ID+N GCP +   + G G  LLS P+
Sbjct: 102 CTASGTPMVIQLLGSDPVWLARNAAQAATISPHGIDLNFGCPAKVVNRHGGGAMLLSTPE 161

Query: 469 KAYQILKTL--VDNLSIPVTCKIRI 537
             + I+  +      +I VT K+R+
Sbjct: 162 LLHTIVSAVRAAVPANIAVTAKMRL 186


>UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep:
           CG10463-PA - Drosophila melanogaster (Fruit fly)
          Length = 604

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 12/35 (34%), Positives = 23/35 (65%)
 Frame = +1

Query: 82  MNYENKIILAPMVRIGTLPMRLLALKYGADIVYTE 186
           +++  K++L+P+  +G LP R +  ++GADI   E
Sbjct: 253 VDFREKLVLSPLTTLGNLPFRRICKEFGADITCGE 287


>UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2;
           Endopterygota|Rep: ENSANGP00000016833 - Anopheles
           gambiae str. PEST
          Length = 594

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 34/141 (24%), Positives = 56/141 (39%)
 Frame = +1

Query: 88  YENKIILAPMVRIGTLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQT 267
           + +K+ L+P+  +G LP R +  +YG DI   E       +       +   T  +   +
Sbjct: 243 FRDKLYLSPLTTVGNLPFRRICKEYGVDITCGEMACAIPIING--AIQEWALTKRH--SS 298

Query: 268 DGTIVFRTCEEEKKKVVLQLGTCDEARALKVAKLVEHDVAAIDINMGCPKEFSIKGGMGV 447
           +     + C    K V        E          + DV  ID+N GCP +     G G 
Sbjct: 299 EDLFGVQLCGHNPKLVTYAAQIIAE----------KADVDFIDLNTGCPIDLIFNQGGGS 348

Query: 448 ALLSKPDKAYQILKTLVDNLS 510
           ALL + +    +LK +V + S
Sbjct: 349 ALLRRQN----VLKVMVQSCS 365


>UniRef50_Q23WS6 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 2973

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 20/62 (32%), Positives = 30/62 (48%)
 Frame = +1

Query: 412 PKEFSIKGGMGVALLSKPDKAYQILKTLVDNLSIPVTCKIRILKTPEATLELVNKLITYQ 591
           PKE  I       +  KP+KA ++   L  N   P   K  I++TP  +LE+ N+L    
Sbjct: 648 PKEKLISDFFPYVMEHKPEKAIEVFAVLDPNKYPPSQIKQLIIQTPNISLEVRNQLTGIY 707

Query: 592 FQ 597
           F+
Sbjct: 708 FE 709


>UniRef50_O75864 Cluster: R32611_1; n=20; Euteleostomi|Rep: R32611_1
           - Homo sapiens (Human)
          Length = 540

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 34/136 (25%), Positives = 59/136 (43%), Gaps = 12/136 (8%)
 Frame = +1

Query: 202 KFLRSKRRFNDILNTVDYVDQTDGTIVFRTCE--EEK------KKVVLQLGTCDEARALK 357
           K LR  + F D+ + +D +D     + ++TCE  EE       K V L+    DE  A  
Sbjct: 26  KLLRQLQEFTDLGHRLDCLDLKGEKLDYKTCEALEEVFKRLQFKVVDLEQTNLDEDGASA 85

Query: 358 VAKLVEHDVAAIDINMGCPKEFSIKGGMGVALLSKPDKAYQILKT----LVDNLSIPVTC 525
           +  ++E+  +A  +N+   K    +G    A + +     Q L      L+D+ S P   
Sbjct: 86  LFDMIEYYESATHLNISFNKHIGTRGWQAAAHMMRKTSCLQYLDARNTPLLDH-SAPFVA 144

Query: 526 KIRILKTPEATLELVN 573
           +   +++  A L L N
Sbjct: 145 RALRIRSSLAVLHLEN 160


>UniRef50_Q6D9Y3 Cluster: Enterobactin synthetase component F; n=4;
           Gammaproteobacteria|Rep: Enterobactin synthetase
           component F - Erwinia carotovora subsp. atroseptica
           (Pectobacterium atrosepticum)
          Length = 1047

 Score = 33.9 bits (74), Expect = 4.0
 Identities = 17/56 (30%), Positives = 29/56 (51%)
 Frame = +1

Query: 130 TLPMRLLALKYGADIVYTEELIDWKFLRSKRRFNDILNTVDYVDQTDGTIVFRTCE 297
           T+P  L A+  G + VY E+L+ W     +R   D L  ++    T+ T+V  +C+
Sbjct: 716 TMPSALRAIIIGGEAVYPEQLVQW-----QRHAPDTLRLINTYGPTETTVVATSCD 766


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 678,035,032
Number of Sequences: 1657284
Number of extensions: 12985697
Number of successful extensions: 30345
Number of sequences better than 10.0: 264
Number of HSP's better than 10.0 without gapping: 29263
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30266
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57851245060
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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