Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Nnor0195
(560 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 186 3e-46
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 184 1e-45
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 168 9e-41
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 167 2e-40
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 158 7e-38
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 157 2e-37
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 148 8e-35
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 144 2e-33
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 136 3e-31
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 132 5e-30
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 131 9e-30
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 130 2e-29
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 130 2e-29
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 130 2e-29
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 121 1e-26
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 119 5e-26
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 114 2e-24
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 110 2e-23
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-22
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 104 1e-21
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 99 4e-20
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 88 2e-16
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 83 6e-15
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 82 8e-15
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 77 3e-13
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 77 4e-13
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 76 5e-13
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 76 7e-13
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 75 2e-12
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 75 2e-12
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 74 2e-12
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 73 5e-12
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 73 6e-12
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 71 1e-11
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 71 2e-11
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 71 2e-11
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 70 3e-11
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 70 3e-11
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 70 3e-11
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 69 1e-10
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 69 1e-10
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 67 2e-10
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 67 2e-10
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 67 3e-10
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 66 5e-10
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 66 7e-10
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 66 7e-10
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 65 1e-09
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 64 2e-09
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 64 2e-09
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 64 3e-09
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 63 4e-09
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 63 4e-09
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 62 9e-09
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 61 2e-08
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 61 2e-08
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 60 3e-08
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 60 3e-08
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 60 3e-08
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 60 3e-08
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 60 5e-08
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 59 6e-08
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 59 6e-08
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 59 6e-08
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 59 8e-08
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 58 2e-07
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 57 2e-07
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 57 2e-07
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 57 2e-07
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 57 3e-07
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 57 3e-07
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 57 3e-07
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 57 3e-07
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 56 4e-07
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 56 4e-07
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 56 6e-07
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 56 6e-07
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 56 7e-07
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 55 1e-06
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 55 1e-06
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 54 2e-06
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 53 4e-06
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 53 5e-06
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 53 5e-06
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 52 7e-06
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 52 7e-06
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 52 9e-06
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 52 9e-06
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 52 1e-05
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 51 2e-05
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 51 2e-05
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 51 2e-05
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 51 2e-05
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 50 3e-05
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 50 4e-05
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 50 4e-05
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 50 4e-05
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 50 5e-05
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 48 1e-04
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 48 1e-04
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 48 1e-04
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 48 1e-04
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 48 1e-04
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 48 2e-04
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 48 2e-04
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 47 3e-04
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 47 3e-04
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 47 3e-04
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n... 47 3e-04
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 46 5e-04
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 46 6e-04
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 45 0.001
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 45 0.001
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 44 0.002
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 44 0.002
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 44 0.002
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 44 0.002
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 44 0.003
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 43 0.004
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 43 0.006
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 41 0.017
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 40 0.030
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 40 0.040
UniRef50_Q014D4 Cluster: Chromosome 08 contig 1, DNA sequence; n... 40 0.040
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 40 0.040
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 40 0.053
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 39 0.069
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 38 0.12
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 38 0.12
UniRef50_O34358 Cluster: Probable serine protease do-like htrA; ... 38 0.12
UniRef50_UPI00015974E8 Cluster: HtrA; n=1; Bacillus amyloliquefa... 38 0.16
UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.21
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 38 0.21
UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 37 0.37
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 36 0.49
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 36 0.65
UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finge... 36 0.85
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 36 0.85
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 35 1.1
UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n... 34 2.0
UniRef50_Q54IK5 Cluster: Putative uncharacterized protein; n=1; ... 34 2.0
UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9; ... 34 2.0
UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;... 34 2.6
UniRef50_UPI000049A32B Cluster: protein kinase; n=1; Entamoeba h... 34 2.6
UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 34 2.6
UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome sh... 33 3.4
UniRef50_A7K8Q9 Cluster: Putative uncharacterized protein z299L;... 33 3.4
UniRef50_Q608X6 Cluster: Hydrophobe/amphiphile Efflux-1 (HAE1) f... 33 3.4
UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein precur... 33 3.4
UniRef50_P83778 Cluster: Malate dehydrogenase, cytoplasmic; n=1;... 33 3.4
UniRef50_UPI0000D9F76A Cluster: PREDICTED: hypothetical protein,... 33 4.6
UniRef50_Q01UG3 Cluster: Putative uncharacterized protein precur... 33 4.6
UniRef50_Q4D3U5 Cluster: Putative uncharacterized protein; n=2; ... 33 4.6
UniRef50_A2R1L8 Cluster: Contig An13c0060, complete genome; n=2;... 33 4.6
UniRef50_O26630 Cluster: UDP-N-acetylmuramyl tripeptide syntheta... 33 4.6
UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3; Lactoco... 33 4.6
UniRef50_Q6NPB9 Cluster: AT22132p; n=2; Drosophila melanogaster|... 33 6.0
UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 33 6.0
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl... 33 6.0
UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1; ... 32 8.0
UniRef50_Q8XN38 Cluster: Probable hexosyltransferase; n=1; Clost... 32 8.0
UniRef50_Q7NV30 Cluster: Probable colicin V production protein; ... 32 8.0
UniRef50_A3PZC4 Cluster: Cytochrome oxidase assembly; n=22; Cory... 32 8.0
UniRef50_A7SI71 Cluster: Predicted protein; n=1; Nematostella ve... 32 8.0
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 186 bits (453), Expect = 3e-46
Identities = 95/163 (58%), Positives = 117/163 (71%)
Frame = +1
Query: 70 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 249
M S +PA A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 250 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 429
IA TPGVAADLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58 IAH-TPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116
Query: 430 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
NA+IV + + AQ+ P+A+V II NPVNST+PI +EV K G
Sbjct: 117 NATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHG 159
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 184 bits (448), Expect = 1e-45
Identities = 92/163 (56%), Positives = 117/163 (71%)
Frame = +1
Query: 70 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 249
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 250 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 429
IA TPGVAADLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58 IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116
Query: 430 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
NA+IV + + AQ+ P+A++ +I NPVNST+PI +EV K G
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHG 159
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 168 bits (408), Expect = 9e-41
Identities = 82/125 (65%), Positives = 100/125 (80%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDAD 363
IGQPL+LL+K +PLV+ L LYDIA V GVAADLSH NTP++V GP EL+ +KD +
Sbjct: 94 IGQPLSLLIKMSPLVSTLHLYDIANVK-GVAADLSHCNTPSQVRDFTGPSELADCLKDVN 152
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 543
VVVIPAGVPRKPGMTRDDLFN NA+IV+ + ++A+N P A + II+NPVNSTVPIA+EV
Sbjct: 153 VVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPVNSTVPIAAEV 212
Query: 544 LGKSG 558
L K G
Sbjct: 213 LKKKG 217
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 167 bits (405), Expect = 2e-40
Identities = 84/147 (57%), Positives = 109/147 (74%), Gaps = 1/147 (0%)
Frame = +1
Query: 121 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNT 300
++FS ++ + K IGQPL+LL+KQNPLVT LALYDI PGVAAD+SH+NT
Sbjct: 14 RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRG-GPGVAADISHINT 72
Query: 301 PAKVSGHKG-PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 477
+ V G++ P L A+K +++++IPAGVPRKPGMTRDDLFNTNASIVRD+A + A+ A
Sbjct: 73 NSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAAEAA 132
Query: 478 PKAIVAIITNPVNSTVPIASEVLGKSG 558
P+A + +I+NPVNSTVPI SEV G
Sbjct: 133 PEANILVISNPVNSTVPIVSEVYKSKG 159
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 158 bits (384), Expect = 7e-38
Identities = 81/136 (59%), Positives = 96/136 (70%)
Frame = +1
Query: 151 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGP 330
FK IGQPLALL+K NPLV+ L LYD+ TPGV AD+SH+NT A V G G
Sbjct: 45 FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVN-TPGVTADISHMNTGAVVRGFLGQ 103
Query: 331 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 510
+L A+ D+V+IPAGVPRKPGMTRDDLFN NA IVR + IA+ P AIV +I+NP
Sbjct: 104 PQLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCEGIAKCCPNAIVNVISNP 163
Query: 511 VNSTVPIASEVLGKSG 558
VNSTVPIA+EV K+G
Sbjct: 164 VNSTVPIAAEVFKKAG 179
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 157 bits (381), Expect = 2e-37
Identities = 80/147 (54%), Positives = 102/147 (69%), Gaps = 1/147 (0%)
Frame = +1
Query: 121 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNT 300
++FSTTS R FK IGQPL++LLK N V+ LAL+DI PGVAAD+ H+NT
Sbjct: 19 RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRGA-PGVAADIGHINT 77
Query: 301 PAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 477
+ V G+ ++ L A+ ADVV+IPAGVPRKPGMTRDDLF TNASIVRD+A + +
Sbjct: 78 TSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETC 137
Query: 478 PKAIVAIITNPVNSTVPIASEVLGKSG 558
P+A ++TNPVNSTVPI + L + G
Sbjct: 138 PEAKYLVVTNPVNSTVPIFKKALERVG 164
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 148 bits (359), Expect = 8e-35
Identities = 77/130 (59%), Positives = 98/130 (75%), Gaps = 5/130 (3%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEE-----LSAA 348
IGQPL+LLLK NP V+ L+L+D+ GVAADLSH+ +PAKV+G++ + + A
Sbjct: 13 IGQPLSLLLKLNPQVSELSLFDVVNAN-GVAADLSHICSPAKVTGYQPSSKEDRDTIQKA 71
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 528
+ ++D+VVIPAGVPRKPGMTR DLFN NASI+RDI SI + P A + II+NPVNSTVP
Sbjct: 72 LVNSDLVVIPAGVPRKPGMTRADLFNINASIIRDIVGSIGKACPNAAILIISNPVNSTVP 131
Query: 529 IASEVLGKSG 558
IA+EVL K G
Sbjct: 132 IAAEVLKKLG 141
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 144 bits (348), Expect = 2e-33
Identities = 66/97 (68%), Positives = 84/97 (86%)
Frame = +1
Query: 268 GVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 447
GVAADLSH++T AKV+ H+GP++L AA++ VV IPAGVPRKPGMTRDDLFNTNASIV+
Sbjct: 7 GVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVK 66
Query: 448 DIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
+++ + A++ PKAI+ II+NPVNSTVPIASEV K+G
Sbjct: 67 NLSEACAKHCPKAIICIISNPVNSTVPIASEVYKKAG 103
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 136 bits (329), Expect = 3e-31
Identities = 66/125 (52%), Positives = 92/125 (73%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDAD 363
+GQPL+LLLK N +++ LALYDI + GVA DLSH+NT A G+ +++ A+K A
Sbjct: 13 VGQPLSLLLKLNTMISELALYDIK-LAEGVATDLSHINTNADCVGYS-TDDIGQALKGAA 70
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 543
VVVIPAGVPR+PG+TRDDLF NA IV+++ ++A++ P A + II+NPVNS +P+A E
Sbjct: 71 VVVIPAGVPRRPGITRDDLFKLNAGIVKNLVSNVAKHCPNARLLIISNPVNSLIPVAVET 130
Query: 544 LGKSG 558
L + G
Sbjct: 131 LKRCG 135
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 132 bits (319), Expect = 5e-30
Identities = 66/138 (47%), Positives = 88/138 (63%)
Frame = +1
Query: 145 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK 324
R K IGQPL+LLLK NP ++ L+LYDI T GV DLSH+NT A V +
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT-GVGVDLSHINTRASVCPFE 84
Query: 325 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 504
G L A+ AD+VVIPAG+PRKPGM R+DL + NAS+ ++A + ++ P A++A IT
Sbjct: 85 GKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFIT 144
Query: 505 NPVNSTVPIASEVLGKSG 558
NP+N VPI + +L G
Sbjct: 145 NPINVIVPIVATILKAKG 162
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 131 bits (317), Expect = 9e-30
Identities = 62/126 (49%), Positives = 89/126 (70%), Gaps = 1/126 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDAD 363
IGQPL+LLLK NP V+ LALYDI+ +T GVA DLSH+NT + G+ E+ ++ ++
Sbjct: 13 IGQPLSLLLKLNPYVSDLALYDISDITAGVAKDLSHINTNSDSEGYNKDEDFKNLLEGSE 72
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAP-KAIVAIITNPVNSTVPIASE 540
+V++ AG+PRKPGMTRDDLF NA I++++ + A+ AP + II+NPVNS +P+ E
Sbjct: 73 LVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVKYAKFAPVHCKLLIISNPVNSLIPVVIE 132
Query: 541 VLGKSG 558
L +G
Sbjct: 133 TLKING 138
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 130 bits (315), Expect = 2e-29
Identities = 64/125 (51%), Positives = 86/125 (68%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDAD 363
+GQPL+LLLK +P V+ LALYDI G+ DLSH+NT + G+ + + + +A
Sbjct: 13 VGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYD-KDSIENTLSNAQ 70
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 543
VV+IPAGVPRKPG+TRDDLF NA IV+ + ++ + AP A + +I+NPVNS VPIA E
Sbjct: 71 VVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVET 130
Query: 544 LGKSG 558
L K G
Sbjct: 131 LKKMG 135
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 130 bits (314), Expect = 2e-29
Identities = 64/99 (64%), Positives = 76/99 (76%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDAD 363
IGQPL+LL+K +PLV+ L LYDIA V GV ADL H NTPAKV+G G EEL+ + D
Sbjct: 89 IGQPLSLLVKMSPLVSALHLYDIANVD-GVTADLGHCNTPAKVAGFTGKEELAGCLAGVD 147
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAP 480
VVVIPAGVPRKPGMTRDDLF NA IVR++ ++A +AP
Sbjct: 148 VVVIPAGVPRKPGMTRDDLFGINAGIVRELVEAVADHAP 186
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 130 bits (314), Expect = 2e-29
Identities = 69/137 (50%), Positives = 95/137 (69%), Gaps = 1/137 (0%)
Frame = +1
Query: 151 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHKG 327
FK IGQPLAL L QN V+ LALYDI V P GVA DLSH KV+G+
Sbjct: 9 FKVTVLGASGAIGQPLALALVQNKRVSELALYDI--VQPRGVAVDLSHFPRKVKVTGYP- 65
Query: 328 PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITN 507
+ + A+ AD+V++ AG+PR+PGMT DDLFNTNA V +++ ++A+ APK+++AII+N
Sbjct: 66 TKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAAVARYAPKSVLAIISN 125
Query: 508 PVNSTVPIASEVLGKSG 558
P+NS VP+A+E L ++G
Sbjct: 126 PLNSMVPVAAETLQRAG 142
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 121 bits (291), Expect = 1e-26
Identities = 62/138 (44%), Positives = 87/138 (63%)
Frame = +1
Query: 145 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK 324
R K IGQPL+LLL++ P + LAL+D++ + G+A DLSH++ KV G
Sbjct: 21 RTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMK-GIATDLSHISQTGKVIGFT 79
Query: 325 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 504
G +EL +A+ ADVVV+ AG+PR PGM RD L N ++ +A +I+ +P+A +A IT
Sbjct: 80 GEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFIT 139
Query: 505 NPVNSTVPIASEVLGKSG 558
NPVN VP A+EVL G
Sbjct: 140 NPVNMIVPAAAEVLMAHG 157
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 119 bits (286), Expect = 5e-26
Identities = 69/133 (51%), Positives = 86/133 (64%), Gaps = 8/133 (6%)
Frame = +1
Query: 184 IGQPLALLL-KQNPLVTRLALYDIAPVTPGVAADLSHV-NTPAKVS------GHKGPEEL 339
IGQ L+LLL +Q P + L+L+D+ GVAADLSHV N +V GHK L
Sbjct: 13 IGQSLSLLLVRQLPYGSTLSLFDVVGAA-GVAADLSHVDNAGVQVKFAEGKIGHKRDPAL 71
Query: 340 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 519
+ K DV V+ AGVPRKPGMTRDDLF NA I+ D+ L+ A ++PKA+ I+TNPVNS
Sbjct: 72 AELAKGVDVFVMVAGVPRKPGMTRDDLFKINAGIILDLVLTCASSSPKAVFCIVTNPVNS 131
Query: 520 TVPIASEVLGKSG 558
TV IA+E L G
Sbjct: 132 TVAIAAEALKSLG 144
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 114 bits (274), Expect = 2e-24
Identities = 70/132 (53%), Positives = 82/132 (62%), Gaps = 16/132 (12%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVT--------RLALYDIAP-VTPGVAADLSHVNTPAKVSGH----- 321
IGQPL+LLLK LALYD+A GVAADLSHVNTP +VS H
Sbjct: 35 IGQPLSLLLKTQLAQVLGDANASLELALYDVAADALAGVAADLSHVNTPVEVSHHVPSSR 94
Query: 322 KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVA 495
+ E L A+ A VVVIPAGVPRKPGMTRDDL N NA I++ +A IA + K V
Sbjct: 95 EDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKGIAGACDLEKVFVL 154
Query: 496 IITNPVNSTVPI 531
+I+NPVNS VP+
Sbjct: 155 VISNPVNSLVPV 166
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 110 bits (264), Expect = 2e-23
Identities = 65/130 (50%), Positives = 80/130 (61%), Gaps = 14/130 (10%)
Frame = +1
Query: 184 IGQPLALLLK---------QNPLVTR--LALYDI-APVTPGVAADLSHVNTPAKVSGHKG 327
IGQ L+LLLK N VT LALYD+ GV ADLSH++TP VS H
Sbjct: 25 IGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPISVSSHSP 84
Query: 328 PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVAII 501
+ + +A +VVIPAGVPRKPGMTRDDLFN NA I+ + SIA+ + K V +I
Sbjct: 85 AGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVLVI 144
Query: 502 TNPVNSTVPI 531
+NPVNS VP+
Sbjct: 145 SNPVNSLVPV 154
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 107 bits (256), Expect = 2e-22
Identities = 62/127 (48%), Positives = 81/127 (63%), Gaps = 6/127 (4%)
Frame = +1
Query: 184 IGQPLALLLK-----QNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSA 345
IGQ L+LLL+ N LAL+D+ V GV ADLSHVNT K+S H + L
Sbjct: 52 IGQSLSLLLRTSLQNNNDNQLHLALFDVNMKVLNGVHADLSHVNTNMKLSLH---DNLRD 108
Query: 346 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 525
++ D+++V+IPAGVPRKPGMTRDDLFN NA I++ IA + V +I+NPVNS +
Sbjct: 109 SLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIAQELNTIDSTPFVLLISNPVNSLL 168
Query: 526 PIASEVL 546
P+ VL
Sbjct: 169 PVLQSVL 175
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 104 bits (250), Expect = 1e-21
Identities = 59/145 (40%), Positives = 80/145 (55%), Gaps = 9/145 (6%)
Frame = +1
Query: 151 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTP--GVAADLSHVNTPAKVSGH 321
FK IGQPL LL+ +P V L ++D+ + P GVA DL H+ A V G+
Sbjct: 81 FKVCVCGGAGGIGQPLCLLMAMDPNVKELCVFDLNVAMVPAQGVATDLGHLEKKAAVKGY 140
Query: 322 ------KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK 483
K + L + +V+IPAG+PRKPG TRDDLF NA I + I + A+ P
Sbjct: 141 VMEVGQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPD 200
Query: 484 AIVAIITNPVNSTVPIASEVLGKSG 558
A++ +I NPVNS VP +E+ K G
Sbjct: 201 AMLGMIVNPVNSVVPAMAELYKKKG 225
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 99 bits (238), Expect = 4e-20
Identities = 60/139 (43%), Positives = 83/139 (59%), Gaps = 15/139 (10%)
Frame = +1
Query: 184 IGQPLALLLKQN-----PLVT----RLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPE 333
IGQ L+LLLK N P T RL+LYD+ G AADLSH++TP + H +
Sbjct: 58 IGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAADLSHIDTPITTTAHYPDD 117
Query: 334 E---LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVAI 498
+ + +A VV+IPAGVPRKPGM+RDDL NA I++ + IA+ + K V +
Sbjct: 118 SNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKSLGEDIAKYCDLNKVHVLV 177
Query: 499 ITNPVNSTVPIASEVLGKS 555
I+NP+NS VP+ + L +S
Sbjct: 178 ISNPINSLVPLLTNTLIRS 196
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 87.8 bits (208), Expect = 2e-16
Identities = 45/124 (36%), Positives = 77/124 (62%)
Frame = +1
Query: 187 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADV 366
G+ ++L+LKQ+P + L LYD + G A DL++V+T +V+ G +++ A+ +++
Sbjct: 41 GKSVSLMLKQSPFIDELCLYDTQSLE-GFANDLNYVDTKCRVTSFFGNKDIQKALTKSNI 99
Query: 367 VVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVL 546
+V+ + LF+ NA IV+D+A SIA+ +PK+ VAI P+NS VP+ SE++
Sbjct: 100 IVVLSCCHAAEPTNYASLFDRNAPIVKDLATSIAKFSPKSTVAIGVEPINSVVPMFSEIM 159
Query: 547 GKSG 558
K G
Sbjct: 160 KKYG 163
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 82.6 bits (195), Expect = 6e-15
Identities = 36/57 (63%), Positives = 46/57 (80%)
Frame = +1
Query: 388 PRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
PRKPGMTRDDLFNTNAS+V + AQ+ P+A++ +I+NPVNST+PIA+EV K G
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVNSTIPIATEVFKKHG 117
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 82.2 bits (194), Expect = 8e-15
Identities = 44/125 (35%), Positives = 78/125 (62%), Gaps = 1/125 (0%)
Frame = +1
Query: 187 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEE-LSAAIKDAD 363
G L+L LKQ+PL+ LA++D T G+A DL++++T KVS PE+ L ++ A
Sbjct: 13 GNCLSLFLKQSPLIDELAIFDNNSSTYGLALDLNYIDTKCKVSTCNHPEKCLEETLQGAK 72
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 543
+V+I V + +++ +NA I+ D+ +I + +P+A++AI+ NP+NS +P+ E+
Sbjct: 73 IVMI---VTDRTSNESNEVLKSNAIILSDLLPNIIKFSPQAMLAIVMNPINSLIPLTMEM 129
Query: 544 LGKSG 558
K+G
Sbjct: 130 YKKAG 134
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 77.0 bits (181), Expect = 3e-13
Identities = 46/124 (37%), Positives = 68/124 (54%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDAD 363
+G LALLLKQN + L L+D T A DL+ ++T K+ + L AI A
Sbjct: 40 VGSNLALLLKQNLDIYELRLFDEENNTNAFACDLNEIDTRTKLKSFSC-KSLKNAIVGAH 98
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 543
VV+ G KPG ++ +LF+ N VR++A+ +A+ P+AI I PV + VP+ SE
Sbjct: 99 VVISTGGCQEKPGSSQRELFDKNLDNVRNVAMFLAEFNPEAIYCIAKPPVEALVPMVSEE 158
Query: 544 LGKS 555
K+
Sbjct: 159 YKKA 162
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 76.6 bits (180), Expect = 4e-13
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A + P V R+ L D P ++ GV D+ H + S + + +++A
Sbjct: 16 VGATFAYTMAIVPGVARMVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAYDDVSKVENA 75
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
D +VI AG PRK M+R DL NA I+RDI + P A +ITNPV+ I S+
Sbjct: 76 DAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTMILSD 135
Query: 541 VLGKSG 558
V+G G
Sbjct: 136 VIGNKG 141
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 76.2 bits (179), Expect = 5e-13
Identities = 41/100 (41%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Frame = +1
Query: 235 LALYDIAPVTP-GVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 411
L LYD+ P P G A DL H +T V+ + IKDAD++VI AGV RK GMTR
Sbjct: 28 LILYDVVPGIPQGKALDLKHFSTILGVNRNILGTNQIEDIKDADIIVITAGVQRKEGMTR 87
Query: 412 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
+DL N I++ +A S+ + KA V ++NP++ V +
Sbjct: 88 EDLIGVNGKIMKSVAESVKLHCSKAFVICVSNPLDIMVNV 127
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 75.8 bits (178), Expect = 7e-13
Identities = 49/124 (39%), Positives = 67/124 (54%), Gaps = 2/124 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSAAIKD 357
IG LALL L + ++D+ P G DL + + V +G + S +KD
Sbjct: 168 IGATLALLSAVKELGD-VVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGSNDYSV-LKD 225
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
ADV+++ AGVPRKPGM+RDDL NA I+ + +I Q P A V ITNP++ V I
Sbjct: 226 ADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVMVYILR 285
Query: 538 EVLG 549
E G
Sbjct: 286 EKCG 289
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 74.5 bits (175), Expect = 2e-12
Identities = 34/67 (50%), Positives = 47/67 (70%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 528
I DA +V+I AGVPRKPGM+R DL TNA IVR +A +IA+ AP A+V +++NP++
Sbjct: 85 IADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEMTA 144
Query: 529 IASEVLG 549
+ V G
Sbjct: 145 LTQLVTG 151
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 74.5 bits (175), Expect = 2e-12
Identities = 45/115 (39%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
IG LA L+ L + L+DIA TP G A D++ + A I A
Sbjct: 14 IGGTLAHLVALKELGD-VVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGTQSYADIAGA 72
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 525
DV ++ AGVPRKPGM+RDDL N +++ + I NAP A V ITNP+++ V
Sbjct: 73 DVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLDAMV 127
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 74.1 bits (174), Expect = 2e-12
Identities = 46/125 (36%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPA-KVSGHKGPEELSAAIKD 357
+G A N V +AL DIA + G A DL+H K G + S +K
Sbjct: 11 VGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGGADYSL-LKG 69
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
++++V+ AG+ RKPGMTR DL + NA I++DIA I +NAP++ + ++TNP++ I
Sbjct: 70 SEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMDVMTYIMW 129
Query: 538 EVLGK 552
+ GK
Sbjct: 130 KESGK 134
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 72.9 bits (171), Expect = 5e-12
Identities = 39/98 (39%), Positives = 56/98 (57%), Gaps = 1/98 (1%)
Frame = +1
Query: 235 LALYDIAPVTP-GVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 411
+ L+DIA TP G D++ + AAI+ ADVV++ AGVPRKPGM+R
Sbjct: 30 VVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTGANDYAAIEGADVVIVTAGVPRKPGMSR 89
Query: 412 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 525
DDL N ++ + I + AP+A V ITNP+++ V
Sbjct: 90 DDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAMV 127
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 72.5 bits (170), Expect = 6e-12
Identities = 44/116 (37%), Positives = 66/116 (56%), Gaps = 5/116 (4%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH----VNTPAKVSGHKGPEELSAA 348
+G+ A L +N L L L D V G A D+ + A+V+G E
Sbjct: 14 VGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGSTNYE----L 69
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
I D+D+VVI AG PRKPGM+R D+ ++N I+ DI ++ + AP+++V I+TNPV+
Sbjct: 70 IADSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVD 125
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 71.3 bits (167), Expect = 1e-11
Identities = 40/124 (32%), Positives = 70/124 (56%), Gaps = 2/124 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVS-GHKGPEELSAAIKD 357
+G A+++ L ++ L DI P G A D++H+++ + + G E I+
Sbjct: 10 VGTAAAVIMGLMKLDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSNEYKD-IEG 68
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
+D++++ AG+PRKPGMTR+ L NA IV +I I + AP +IV + TNP+++ +
Sbjct: 69 SDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLDAMTYVMW 128
Query: 538 EVLG 549
+ G
Sbjct: 129 KATG 132
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 70.5 bits (165), Expect = 2e-11
Identities = 41/146 (28%), Positives = 76/146 (52%)
Frame = +1
Query: 118 AKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVN 297
+++F + Q++ + +GQ LA L+KQNP ++ L L + V +A D +H +
Sbjct: 11 SRHFCSKPQKHVQVCILGADTLLGQSLAFLIKQNPAISGLHLQGTSKVE-SMALDFNHFD 69
Query: 298 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 477
T +V + + +S ++K AD+VV+ M+ L V +A + A+ A
Sbjct: 70 TRCRVHSYYDMDSVSKSVKCADIVVMLGLNTSTSKMSIPKLVMAEGVRVAKLAETCAKYA 129
Query: 478 PKAIVAIITNPVNSTVPIASEVLGKS 555
PKA++ + P++ T+PI +EV +S
Sbjct: 130 PKAVIVVAVTPISVTLPIVAEVYKQS 155
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/127 (33%), Positives = 72/127 (56%), Gaps = 5/127 (3%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHK----GPEELSAA 348
+G A +L N + + + D+ V+ G A D+ A++ G G A
Sbjct: 12 VGATCANVLAFNEVADEVVMLDVKEGVSEGKAMDMMQT---AQLLGFDTTIVGCTNDYAQ 68
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 528
++DVVVI +G+PRKPGMTR++L NA IV+ +A ++ + +P AI+ +I+NP+++
Sbjct: 69 TANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMDTMTY 128
Query: 529 IASEVLG 549
+A + LG
Sbjct: 129 LALKSLG 135
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 70.1 bits (164), Expect = 3e-11
Identities = 43/113 (38%), Positives = 68/113 (60%), Gaps = 5/113 (4%)
Frame = +1
Query: 226 VTRLALYDI-APVTPGVAADLSHV----NTPAKVSGHKGPEELSAAIKDADVVVIPAGVP 390
++++AL DI + A DLSH+ N ++SG E L +K++D+VVI AG
Sbjct: 26 ISQIALIDIFGDLAKARALDLSHLASVYNKKTEISG-SSDETL---LKNSDIVVITAGKT 81
Query: 391 RKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLG 549
R+ G +R DL N NA I+ A ++A+ AP+AI+ +ITNPV++ +A + G
Sbjct: 82 RQAGQSRADLLNDNAKIISSCAKNVAKYAPEAIIILITNPVDTLAFVAYKASG 134
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 70.1 bits (164), Expect = 3e-11
Identities = 47/129 (36%), Positives = 68/129 (52%), Gaps = 8/129 (6%)
Frame = +1
Query: 187 GQPLALLLKQNPLVTRLAL----YDIAPVTPGVAADLSHVNTPAK----VSGHKGPEELS 342
G +A +L N + L YD+A G A D+S A+ V KGPE++
Sbjct: 16 GSTVAFILAMNGSCHHVMLRGRNYDVAK---GKALDMSQAANAARQHTIVKAAKGPEDME 72
Query: 343 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 522
+ DVV+I AG PR PGM+RDDL NA IV+ + I + AP AIV +++NP++
Sbjct: 73 GS----DVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNPLDVM 128
Query: 523 VPIASEVLG 549
+A + G
Sbjct: 129 TYVALKETG 137
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 70.1 bits (164), Expect = 3e-11
Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 1/123 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G AL L ++ L + +AL D+ P + G+A D+ H S + A+ A
Sbjct: 134 VGAMTALRLAESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGSDDLVALAGA 193
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
+ +VI AG PR+PGM+R DL NA I+ + I +AP + + I++NP+ +A++
Sbjct: 194 EYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPLEEMTHLAAQ 253
Query: 541 VLG 549
G
Sbjct: 254 QTG 256
>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Plicopurpura patula
Length = 229
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/48 (70%), Positives = 38/48 (79%)
Frame = +1
Query: 415 DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
DLFNTNA IVRD+ IA+ P A++ IITNPVNSTVPIASEVL K G
Sbjct: 1 DLFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVNSTVPIASEVLKKRG 48
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 68.5 bits (160), Expect = 1e-10
Identities = 31/65 (47%), Positives = 45/65 (69%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 534
DADV+V+ AG+PRKPG TR DL NA+I++ +A+ P+AIV ++TNPV+ +A
Sbjct: 73 DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVDVLTYVA 132
Query: 535 SEVLG 549
+V G
Sbjct: 133 LKVSG 137
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 67.3 bits (157), Expect = 2e-10
Identities = 39/125 (31%), Positives = 73/125 (58%), Gaps = 6/125 (4%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALY--DIAPVTPGVAADLSHV----NTPAKVSGHKGPEELSA 345
+G +A L + + L+ DI P GV D+S + P + G EE++
Sbjct: 14 VGSHIAFLGAMRHIAKEILLFSNDI-PRCKGVGLDISQAAAIFDIPILIKGCNSYEEIA- 71
Query: 346 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 525
+++VV+I AG PR P MTR+DL NASI+++I+ ++A+ AP++++ +++NP+++
Sbjct: 72 ---ESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLDAMC 128
Query: 526 PIASE 540
+A +
Sbjct: 129 LVAKQ 133
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/108 (38%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Frame = +1
Query: 235 LALYDIAP-VTPGVAADLSHVN--TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 405
++LYDIA ADL+H TPA V G G + A D+DVV I AG +KPG
Sbjct: 38 VSLYDIAKDKVEAEVADLAHGTQFTPASVMG--GADVHDTA--DSDVVFITAGARQKPGQ 93
Query: 406 TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLG 549
TR DL NA+I+R + + + +P A+ ++TNP + +A E G
Sbjct: 94 TRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNPCDVLTVVAQEATG 141
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 66.9 bits (156), Expect = 3e-10
Identities = 42/116 (36%), Positives = 62/116 (53%), Gaps = 2/116 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTP-AKVSGHKGPEELSAAIKD 357
+G +A L + +AL DI V A D++ G ++ A I+
Sbjct: 11 VGASIAYALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTAGGDDF-ALIEA 69
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 525
+D+VV+ AG PRK G TR+DL NA +V+ A +IA+ AP AIV I+TNP++ V
Sbjct: 70 SDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLDVMV 125
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 66.1 bits (154), Expect = 5e-10
Identities = 37/90 (41%), Positives = 57/90 (63%), Gaps = 2/90 (2%)
Frame = +1
Query: 283 LSHVNTPAKVSGHK-GPE-ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 456
L+ ++ A+V G+ PE E ++ +D+VVI AG PR+PGM+R+DL N I+ IA
Sbjct: 59 LAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIA 118
Query: 457 LSIAQNAPKAIVAIITNPVNSTVPIASEVL 546
I + AP AIV ++TNPV+ +A ++L
Sbjct: 119 DRIKRYAPDAIVIVVTNPVDVMTYVAYKLL 148
>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 342
Score = 65.7 bits (153), Expect = 7e-10
Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 5/148 (3%)
Frame = +1
Query: 130 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP----GVAADLSHVN 297
S T+ + K +GQPL+LLLK NP V L + A G+AADLSH++
Sbjct: 8 SLTALKKGKVVLFGCSNAVGQPLSLLLKMNPHVEELVCCNTAADDDVPGSGIAADLSHID 67
Query: 298 TPAKVSGHKGPEELSAAIKDADVVVIPAGVP-RKPGMTRDDLFNTNASIVRDIALSIAQN 474
T KV + A ++DA ++++ G RD A +R + ++A +
Sbjct: 68 TLPKVHYATDEGQWPALLRDAQLILVCFGSSFDLLREDRDIALKAAAPTMRRVMAAVASS 127
Query: 475 APKAIVAIITNPVNSTVPIASEVLGKSG 558
VA++++PVN+ P +E+L SG
Sbjct: 128 DTTGNVAVVSSPVNALTPFCAELLKASG 155
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 65.7 bits (153), Expect = 7e-10
Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L + L D+ G A DL H TP + + A +K +
Sbjct: 11 VGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIH-GTPFTRRANIYAGDY-ADLKGS 68
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
DVV++ AGVP+KPG TR L NA ++++IA ++++ AP +IV ++TNPV+
Sbjct: 69 DVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVD 120
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 64.9 bits (151), Expect = 1e-09
Identities = 39/125 (31%), Positives = 60/125 (48%), Gaps = 1/125 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPG-VAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+GQ +A N + LYD+ P P ++ H +V I A
Sbjct: 12 VGQTIAYNTIVNGYADEVMLYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDDISGA 71
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
D+VVI AG PRKPGM+R DLF NA I+ D+A + + A+ ++ NPV+ + +
Sbjct: 72 DIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVDMMASVFMK 131
Query: 541 VLGKS 555
G++
Sbjct: 132 YSGEN 136
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/91 (40%), Positives = 53/91 (58%)
Frame = +1
Query: 277 ADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 456
AD++ + P K+ + G E +A DADVVVI AG+PRKPG TR DL N N +I++ I
Sbjct: 53 ADITPLTNPVKI--YAGTYEDAA---DADVVVITAGIPRKPGETRLDLVNKNTTILKSII 107
Query: 457 LSIAQNAPKAIVAIITNPVNSTVPIASEVLG 549
I ++ + I +NPV+ IA + G
Sbjct: 108 KPIVKSGFTGVFVISSNPVDILTTIAQRISG 138
>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
Length = 477
Score = 64.5 bits (150), Expect = 2e-09
Identities = 30/52 (57%), Positives = 38/52 (73%)
Frame = +1
Query: 403 MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
MTRDDLF N IV+ + +IA N P A++ +I+NPVNSTVPIA+EVL G
Sbjct: 1 MTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVNSTVPIAAEVLKAKG 52
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 63.7 bits (148), Expect = 3e-09
Identities = 34/125 (27%), Positives = 64/125 (51%), Gaps = 1/125 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G +A +L + + + D+ T G+A D+ H + K + ++
Sbjct: 9 VGSTVAFILATQGICQEIIIKDLNLDTARGIALDMGHAASATKTHTIVRVANEPSDLRGC 68
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
DVVV AG PR+PGM+RDDL NA ++R + + ++++ +++NP+++ V A +
Sbjct: 69 DVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLDAMVYTAIK 128
Query: 541 VLGKS 555
G S
Sbjct: 129 ESGLS 133
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 63.3 bits (147), Expect = 4e-09
Identities = 38/123 (30%), Positives = 64/123 (52%), Gaps = 1/123 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G AL L ++ L D+A P G A D++H+ + + +K +
Sbjct: 10 VGGDAALFSALKRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSNNFEDMKGS 69
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
++VV+ AG RKPGMTR DL NASIV+ + ++ + A +++ +TNP++ I +
Sbjct: 70 NIVVVVAGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLDPMAYITYK 129
Query: 541 VLG 549
V G
Sbjct: 130 VSG 132
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 63.3 bits (147), Expect = 4e-09
Identities = 38/124 (30%), Positives = 65/124 (52%), Gaps = 2/124 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSAAIKD 357
+G A+ L + + L DI P G A D++H+ + +G + S ++
Sbjct: 10 VGGDAAMFCALRRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSNDYSD-MEG 68
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
+D+VV+ AG RKPGMTR DL NA IV+ + + ++A +++ +TNP++ IA
Sbjct: 69 SDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLDPITYIAY 128
Query: 538 EVLG 549
+ G
Sbjct: 129 KTSG 132
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 62.1 bits (144), Expect = 9e-09
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 2/124 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSH-VNTPAKVSGHKGPEELSAAIKD 357
+G A L L + + + DI G A DLSH V+ V G E + KD
Sbjct: 16 VGSTTAYALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAGDYEDT---KD 72
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
+D+V+I AG KPG TR DL N N I + I + + +PK+I+ +++NPV+ +
Sbjct: 73 SDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVDILTYVTY 132
Query: 538 EVLG 549
++ G
Sbjct: 133 KLSG 136
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 61.3 bits (142), Expect = 2e-08
Identities = 22/56 (39%), Positives = 43/56 (76%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
++ +DV+V+ AG+ RKPGM+R+DLF+ N I+ D++ +I + +P +I+ +++NP +
Sbjct: 74 MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPAD 129
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 10/132 (7%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPA----KVSGHKGPEELSAA 348
IG +A L+ Q L + L+DI P G A D SH N A KVSG ++L+ A
Sbjct: 15 IGGVMATLIVQKNLGD-VVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGA 73
Query: 349 IKDADVVVIPAGVPRKPGMT-----RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPV 513
DVV++ AG + PG + RDDL N I+ +I I +N P A + ++TNPV
Sbjct: 74 ----DVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPV 129
Query: 514 NSTVPIASEVLG 549
+ V + + G
Sbjct: 130 DVMVQLLHQHSG 141
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 60.5 bits (140), Expect = 3e-08
Identities = 27/65 (41%), Positives = 44/65 (67%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 534
D+DVVVI AG+ RKPGM+R++L + NA IV + + Q++P + + I++NPV+ +A
Sbjct: 71 DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVDIMTYVA 130
Query: 535 SEVLG 549
+ G
Sbjct: 131 FKESG 135
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 60.5 bits (140), Expect = 3e-08
Identities = 29/67 (43%), Positives = 44/67 (65%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 528
+KD D+VVI AG RK G +RDDL NA IV + +++ APK+I+ ++TNP++ V
Sbjct: 67 LKDFDIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLDIMVY 126
Query: 529 IASEVLG 549
+A + G
Sbjct: 127 VAFKESG 133
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 60.5 bits (140), Expect = 3e-08
Identities = 39/126 (30%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNT---PAKVSGHKGPEELSAAI 351
+G LA Q + + L DIA D+ H ++ + G PE
Sbjct: 19 VGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGSDDPE----IC 74
Query: 352 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
+DAD+VVI AG +KPG +R +L +I++ I ++ + AP AI +ITNPV+ +
Sbjct: 75 RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVDIATHV 134
Query: 532 ASEVLG 549
A ++ G
Sbjct: 135 AQKLTG 140
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 60.1 bits (139), Expect = 3e-08
Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 2/107 (1%)
Frame = +1
Query: 235 LALYDIAPVT-PGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 411
L LYD+ + G++ +L+ P K+ G E++ A + DV +I AGVPRKPGM R
Sbjct: 47 LHLYDLNDMALKGLSMELTDCCLP-KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQR 105
Query: 412 DDLFNTNASIVRDIALSIAQNAPKAI-VAIITNPVNSTVPIASEVLG 549
DL N N ++ ++ + K + V ++ NP N+ + + G
Sbjct: 106 SDLINVNKKVMEMNGKALGTYSNKDVRVVVVANPANTNAYVICKTSG 152
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 59.7 bits (138), Expect = 5e-08
Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHK----GPEELSAA 348
+G LA L Q V + L DI P G+ DL V GH G + A
Sbjct: 19 VGSALAQRLIQGN-VADVVLLDIVEGRPQGITLDLLEA---CGVEGHTCRITGTNDY-AQ 73
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 528
+DV+V+ AG R+PGM+RDDL TN IV ++ ++P+A V ++TNP+++
Sbjct: 74 TAGSDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDAMSH 133
Query: 529 IASEVLG 549
+A G
Sbjct: 134 VAWRASG 140
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 59.3 bits (137), Expect = 6e-08
Identities = 27/67 (40%), Positives = 45/67 (67%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 528
I+ + VVV+ AG RKPGM+R+DL + N I+ ++A I ++AP ++V ++TNP++
Sbjct: 72 IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMDLMAY 131
Query: 529 IASEVLG 549
I +V G
Sbjct: 132 ILWKVTG 138
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 59.3 bits (137), Expect = 6e-08
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 1/123 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L Q+ L + + + DI A DL+ K K + A KD+
Sbjct: 17 VGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSVDIKSGDY--ADTKDS 74
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
D+V+I AGV KPG TR D+ N N I + I + + +P +I+ +++NPV+ I +
Sbjct: 75 DIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVDILTYITYK 134
Query: 541 VLG 549
+ G
Sbjct: 135 LSG 137
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 59.3 bits (137), Expect = 6e-08
Identities = 39/123 (31%), Positives = 54/123 (43%), Gaps = 1/123 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L QN + L + D+ G DL V + E A +DA
Sbjct: 16 VGSSFAFSLVQNCALDELVIVDLVKTHAEGDVKDLEDVAAFTNATNIHTGEYADA--RDA 73
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
D+VVI AGVPRKPG +R DL N N I+ I + + I +NPV+ +
Sbjct: 74 DIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVISSNPVDILTSMTQR 133
Query: 541 VLG 549
+ G
Sbjct: 134 LSG 136
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 58.8 bits (136), Expect = 8e-08
Identities = 37/83 (44%), Positives = 43/83 (51%)
Frame = +1
Query: 268 GVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 447
G A DLSH P S K A KDAD+VVI AG+P+KPG TR DL N I +
Sbjct: 45 GEAMDLSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFK 103
Query: 448 DIALSIAQNAPKAIVAIITNPVN 516
I I + I I TNPV+
Sbjct: 104 QIVRGIMDSGFDGIFLIATNPVD 126
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 57.6 bits (133), Expect = 2e-07
Identities = 41/119 (34%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSH-VNTPAKVSGHKGPEELSAAIKD 357
+G +A L Q L + + L D G A D+SH + + + G E I D
Sbjct: 15 VGSTIAYTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIYAGEYE---DIAD 71
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 534
A VV+I AG +KPG TR DL NA+I+R I I + + I+ I++NPV+ +A
Sbjct: 72 ASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVDILTEVA 130
>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000020184 - Nasonia
vitripennis
Length = 352
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 1/144 (0%)
Frame = +1
Query: 130 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAK 309
++++ RN K G+ LAL LKQ+ L+ LA+YD P T G+ +LSH+++ +
Sbjct: 29 TSSNSRNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP-TRGLLLELSHMDSRCR 87
Query: 310 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRD-DLFNTNASIVRDIALSIAQNAPKA 486
SA D+ G + +T D + A + I + PKA
Sbjct: 88 TIVEDEASTTSACNGKRDLERALTGA-KIVAITLDGESIREEAEYLEKILSGLLGCCPKA 146
Query: 487 IVAIITNPVNSTVPIASEVLGKSG 558
+VA+++ VNS VP+ E+ ++G
Sbjct: 147 LVALVSRRVNSLVPMLYELYKRAG 170
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 57.2 bits (132), Expect = 2e-07
Identities = 35/83 (42%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 268 GVAADLSHVN--TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 441
G D H N T +K + ++ S + DAD+VVI AG K G TRDDL N+ I
Sbjct: 40 GEMMDFGHANSLTFSKNIRLRAGDDYSL-LTDADIVVITAGAQIKEGQTRDDLAEINSRI 98
Query: 442 VRDIALSIAQNAPKAIVAIITNP 510
DIA I AP AI+ ++TNP
Sbjct: 99 TVDIAQKIETVAPNAILLVVTNP 121
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/125 (29%), Positives = 65/125 (52%), Gaps = 3/125 (2%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELS---AAIK 354
+G LA L + + L + + G A D+S A V G + S A
Sbjct: 12 VGATLAQRLIEKDFADVVMLDVVEGIPQGKALDISQ---SASVLGFRHTITGSNDYAQTA 68
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 534
+++VVI AG+ RKPGMTR++L N I+ D+ + + +P+A + +++NPV++ +A
Sbjct: 69 GSEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDTMTYLA 128
Query: 535 SEVLG 549
++ G
Sbjct: 129 WKLSG 133
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 56.8 bits (131), Expect = 3e-07
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 6/111 (5%)
Frame = +1
Query: 235 LALYDIAPVTP-GVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG--- 402
+ L+D+ P P G A DL H A A+++ ADVV+I AG+ + G
Sbjct: 36 VVLFDVVPNMPAGKALDLCHTAAVADNGVRVQGANSYASLEGADVVIITAGITKAAGKSD 95
Query: 403 --MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLG 549
+R DL N I+R++ +I Q P A V ITNP++ V E G
Sbjct: 96 QEWSRKDLLPVNVKILREVGAAIKQFCPHAFVINITNPLDVMVAALREAAG 146
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 56.8 bits (131), Expect = 3e-07
Identities = 45/132 (34%), Positives = 65/132 (49%), Gaps = 10/132 (7%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPA----KVSGHKGPEELSAA 348
IG +A L+ Q L + ++D+ P G A D SH N A KV+G ++L
Sbjct: 8 IGGVMATLIVQKNLGD-VVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDL--- 63
Query: 349 IKDADVVVIPAGVPRKPGMT-----RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPV 513
K ADVV++ AG + PG + RDDL N I+ +I I P A + ++TNPV
Sbjct: 64 -KGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPV 122
Query: 514 NSTVPIASEVLG 549
+ V + E G
Sbjct: 123 DVMVQLLFEHSG 134
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 56.8 bits (131), Expect = 3e-07
Identities = 41/129 (31%), Positives = 66/129 (51%), Gaps = 7/129 (5%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIA---PVTPGVAADLSHV----NTPAKVSGHKGPEELS 342
+G +A + Q P V + LY G+A D+ T +V+ P+EL
Sbjct: 13 VGSYVAHAVSQFPHVQEMCLYGRPGNEQYLDGLAHDMMDSFAARGTNTRVTFGTTPKEL- 71
Query: 343 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 522
+ +D++V+ +GVPRK TR DL NA IV+ A + + AP+AI+ ++TNPV+
Sbjct: 72 ---RGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVDIM 128
Query: 523 VPIASEVLG 549
+A + G
Sbjct: 129 TTVALKYSG 137
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 56.8 bits (131), Expect = 3e-07
Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKD-- 357
+G+ AL L + V L L ++ ++ G E SA I++
Sbjct: 12 VGRATALCLAEEEAVKTLHLISRKESLEQNLGEVLDMSDALAAKGVSVKLENSADIENVY 71
Query: 358 -ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 534
+ +VVI AGVPR M RDDL N IV D A IA+ AP +I+ ++TNPV+ +A
Sbjct: 72 GSRIVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVDVMTYVA 131
Query: 535 SEVLG 549
G
Sbjct: 132 LRYSG 136
>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to mitochondrial malate dehydrogenase
- Nasonia vitripennis
Length = 299
Score = 56.4 bits (130), Expect = 4e-07
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
Frame = +1
Query: 202 LLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPA 381
+LLKQNP + + L D D+ H++T + H + +++ D+V +
Sbjct: 1 MLLKQNPAIKEIRLIDTDNSLMSPVCDMRHIDTSTTIR-HFRKNSILDGLRNTDIVALMD 59
Query: 382 GVPRKPGMTRDDL-FNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
G + F +++ V+ +A + PKA+VA+ T+PV +T+P+ SE+ SG
Sbjct: 60 ETDFMMGNKGPFMQFVNSSNYVKSVAECMINVCPKALVAVFTHPVTATLPLVSEIYKYSG 119
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 56.4 bits (130), Expect = 4e-07
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G +A L NPL + L L + + G A DL+H + E++ + KD+
Sbjct: 11 VGSAIAFALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKISSGEIADS-KDS 69
Query: 361 DVVVIPAGVP-RKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 519
DV++ A VP R P TR ++ N I+RD +A+ +P AIV +++NPV++
Sbjct: 70 DVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVDA 123
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 56.0 bits (129), Expect = 6e-07
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +1
Query: 352 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
KDAD++VI AGVPR PG TR D+ + + VRDI ++ + K I+ ITNP +
Sbjct: 71 KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPADIIADF 130
Query: 532 ASEVLG 549
+ G
Sbjct: 131 VRKATG 136
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 56.0 bits (129), Expect = 6e-07
Identities = 41/130 (31%), Positives = 57/130 (43%), Gaps = 3/130 (2%)
Frame = +1
Query: 136 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPV---TPGVAADLSHVNTPA 306
TS + K +G A L + L + +I + G A DLSH A
Sbjct: 2 TSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSHAL--A 59
Query: 307 KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA 486
S K + DAD+VVI AG P+KPG TR DL N +I + I + ++ K
Sbjct: 60 FTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKG 119
Query: 487 IVAIITNPVN 516
I + NPV+
Sbjct: 120 IFLVAANPVD 129
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 55.6 bits (128), Expect = 7e-07
Identities = 26/56 (46%), Positives = 37/56 (66%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
+KDAD +VI AG P+KPG TR +L N I+R+IAL + ++ I I+ NPV+
Sbjct: 69 LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD 124
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 55.2 bits (127), Expect = 1e-06
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +1
Query: 319 HKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI 498
H G EL+ DA VV++ AG +KPG +R DL NA I R++ I + AP A++ +
Sbjct: 59 HGGHSELA----DAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLV 114
Query: 499 ITNPVNSTVPIASEV 543
+NPV+ +A+++
Sbjct: 115 TSNPVDLLTDLATQL 129
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 54.8 bits (126), Expect = 1e-06
Identities = 25/70 (35%), Positives = 44/70 (62%)
Frame = +1
Query: 310 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI 489
V G +E +K +D+VVI AG+PR+ GM+R+DL N I++ +I + A +I
Sbjct: 73 VKGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYAKDSI 132
Query: 490 VAIITNPVNS 519
+ +++NPV++
Sbjct: 133 IIVVSNPVDT 142
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 2/124 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH-VNTPAKVSGHKGPEELSAAIKD 357
+G A L Q+ +A+ D+ G A DL + +V H G + A D
Sbjct: 16 VGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQVDIHAGDKTDYA---D 72
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
+D+VV+ AG ++ G TR DL NASI+ IA IA++ ++ I++NPV+ A
Sbjct: 73 SDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVDILTRAAL 132
Query: 538 EVLG 549
+ G
Sbjct: 133 KASG 136
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 53.2 bits (122), Expect = 4e-06
Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = +1
Query: 262 TPGVAADLSH-VNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 438
T G AAD +H + + +G E +A +DVVVI AG+PR+PG TR DL NA
Sbjct: 42 TVGQAADTNHGIAYDSNTRVRQGGYEDTAG---SDVVVITAGIPRQPGQTRIDLAGDNAP 98
Query: 439 IVRDIALSIAQNAPKAIVAIITNPVN 516
I+ DI S+ ++ I +NPV+
Sbjct: 99 IMEDIQSSLDEHNDDYISLTTSNPVD 124
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 52.8 bits (121), Expect = 5e-06
Identities = 47/141 (33%), Positives = 65/141 (46%), Gaps = 7/141 (4%)
Frame = +1
Query: 115 GAKNFSTTSQRN--FKXXXXXXXXX--IGQPLALLLKQNPLVTRLALYDI-APVTPGVAA 279
G+K FS S R+ FK +G A L + L + + D+ G A
Sbjct: 4 GSKVFSNDSVRSSSFKSIKIVIVGAGNVGSTTAFTLLLSGLAAEIVIIDLNKKKAEGEAM 63
Query: 280 DLSHVNTPAKVSGHKGPEELS--AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 453
DL+H A +S H+ L KDA VVI AG +KPG TR DL N SI ++I
Sbjct: 64 DLNHA---APLS-HETRVYLGDYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFKEI 119
Query: 454 ALSIAQNAPKAIVAIITNPVN 516
+ + AI+ + TNPV+
Sbjct: 120 LREVTKYTKDAILLVATNPVD 140
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 52.8 bits (121), Expect = 5e-06
Identities = 25/56 (44%), Positives = 38/56 (67%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
+KD DVVVI AG P+KPG TR ++ NA I+ +IA +I ++ K + ++ NPV+
Sbjct: 71 LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVD 126
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 52.4 bits (120), Expect = 7e-06
Identities = 26/66 (39%), Positives = 37/66 (56%)
Frame = +1
Query: 352 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
KDAD+VVI AG P KPG +R D +A IV I + ++ I ++TNPV+S
Sbjct: 74 KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVDSIAQY 133
Query: 532 ASEVLG 549
++ G
Sbjct: 134 VYQLSG 139
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/92 (31%), Positives = 48/92 (52%)
Frame = +1
Query: 268 GVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 447
G A D+S +G K A K AD++++ AG P+K G TR ++ N+ I++
Sbjct: 41 GHAMDMSDAIALNSTTGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMK 100
Query: 448 DIALSIAQNAPKAIVAIITNPVNSTVPIASEV 543
DIAL I ++ +I+NPV+ + +V
Sbjct: 101 DIALEIKKSGFNGFTIVISNPVDILATVFQKV 132
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 52.0 bits (119), Expect = 9e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSGH---KGPEELSAAI 351
+G A + + + L D+ A D++H P VS G ++LS A
Sbjct: 2 VGSAAAFACIMRGVASEIVLVDLDTARAQAEAEDIAHA-VPFSVSARIVAGGYDDLSGA- 59
Query: 352 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
DVV++ GV +KPG +R +L + NA + R + + + AP AI+ I +NPV+ +
Sbjct: 60 ---DVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVDIMTHV 116
Query: 532 ASEVLG 549
+ G
Sbjct: 117 TQALSG 122
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 52.0 bits (119), Expect = 9e-06
Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSH-VNTPAKVSGHKGPEELSAAIKD 357
+G A + L L D+ G A D++H + ++S + G + +KD
Sbjct: 18 VGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAGDY---SDVKD 74
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
DV+V+ AG RKPG TR DL N I +++ +I + ++ +++NPV+
Sbjct: 75 CDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPVD 127
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 51.6 bits (118), Expect = 1e-05
Identities = 26/66 (39%), Positives = 41/66 (62%)
Frame = +1
Query: 352 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
+DAD+VVI AG +KPG +R DL + NA I++ I +I ++ I+ I +NPV+ +
Sbjct: 72 QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVDVLTYV 131
Query: 532 ASEVLG 549
A + G
Sbjct: 132 AWQASG 137
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 51.2 bits (117), Expect = 2e-05
Identities = 38/115 (33%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
IG +A L L LYD A GVA ++ H ++ A+ DA
Sbjct: 18 IGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGL--NLTFTSDIKEALTDA 75
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNPVNST 522
+V G PRK GMTR+DL NA I + I P V II NP + T
Sbjct: 76 KYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPADIT 130
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 5/116 (4%)
Frame = +1
Query: 184 IGQPLALLLK-QNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSAAIKD 357
+G A L N LV L + D+ G DL+H K K L KD
Sbjct: 15 VGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLK----KNINVLFGTYKD 70
Query: 358 ---ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
AD+VVI AG+ +KPG TR DL + N+ I +DI ++ + I + +NPV+
Sbjct: 71 CANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVD 126
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 50.8 bits (116), Expect = 2e-05
Identities = 23/64 (35%), Positives = 38/64 (59%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
AD+VVI AG+PRK R L + NA+++ D+ +P I+ ++TNP++ +A
Sbjct: 68 ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQLAY 127
Query: 538 EVLG 549
+V G
Sbjct: 128 QVSG 131
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 50.8 bits (116), Expect = 2e-05
Identities = 26/67 (38%), Positives = 38/67 (56%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 528
+ +D+VVI AG PR PG R DL NA I+ +A +I AP + ++TNPV+
Sbjct: 71 VAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVDVMTC 130
Query: 529 IASEVLG 549
+A + G
Sbjct: 131 VALKYSG 137
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 50.4 bits (115), Expect = 3e-05
Identities = 36/115 (31%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
IG +A L + LYD AP GVA +L H + ++ A+ A
Sbjct: 18 IGSNMAQTALMMKLTPNICLYDPYAPALEGVAEELYHCAFEGVNLTYTS--DIKEALSGA 75
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNPVNST 522
+V G RK GMTR+DL NA I I Q P V ++ NP + T
Sbjct: 76 KYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNPADIT 130
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 50.0 bits (114), Expect = 4e-05
Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
Frame = +1
Query: 343 AAIKDADVVVIPAGVPRK-PGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 519
AA+ +A ++V+ AG ++ P TR L NA I R+I + + ++AP AI+ + TNPV+
Sbjct: 67 AALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVDV 126
Query: 520 TVPIASEV 543
I E+
Sbjct: 127 LTYICQEL 134
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 50.0 bits (114), Expect = 4e-05
Identities = 24/66 (36%), Positives = 39/66 (59%)
Frame = +1
Query: 352 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
KDAD++VI AG P++PG TR +L N+ I++ IA +I + + I +NP + +
Sbjct: 72 KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNPCDVLTTV 131
Query: 532 ASEVLG 549
+V G
Sbjct: 132 YQQVTG 137
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 50.0 bits (114), Expect = 4e-05
Identities = 25/64 (39%), Positives = 35/64 (54%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
A +VV+ AG + PG +R DL NA I RDI ++ Q A + + TNPV+ +A
Sbjct: 69 ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVDVLTHVAR 128
Query: 538 EVLG 549
V G
Sbjct: 129 TVTG 132
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 49.6 bits (113), Expect = 5e-05
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
Frame = +1
Query: 235 LALYDI--APVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMT 408
LALYD A V V DL+H + G ++++ A +VV+ AG + PG +
Sbjct: 46 LALYDTNSAKVRAEVL-DLNHGSQFVPECRVGGSDDIAVTAGSA-IVVVTAGAKQHPGQS 103
Query: 409 RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVL 546
R DL N ++ + + + +++P A+V +TNPV+ AS V+
Sbjct: 104 RLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVDVVTYAASSVV 149
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 48.4 bits (110), Expect = 1e-04
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Frame = +1
Query: 349 IKDADVVVI-PAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 525
+ D+D+++I AGV K G TR D + NA I+R + + AP +IV II+NPV+
Sbjct: 71 LADSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVDVLT 130
Query: 526 PIA 534
IA
Sbjct: 131 RIA 133
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 48.4 bits (110), Expect = 1e-04
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L Q L + L D G A DL+H P + E A + A
Sbjct: 21 VGASFAFALLQRRLAAEIVLIDANHKKAEGEAMDLNHA-VPFGAATRIWAGEY-ADCRGA 78
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
V VI AG ++PG TR L + N +I + I + ++ P ++ I TNPV+
Sbjct: 79 AVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVD 130
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 48.4 bits (110), Expect = 1e-04
Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNT---PAKVSGHKGPEELSAAI 351
+G +A + L T + L D+ G A D SH + + H G E
Sbjct: 15 VGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFHLGDYE---DC 71
Query: 352 KDADVVVIPAGVPRKPGMTRD--DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 525
KDA+++VI AG +PG T D L TNA I+ + I + +A++ +ITNP++
Sbjct: 72 KDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLDVAT 131
Query: 526 PIAS 537
+ S
Sbjct: 132 YVVS 135
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 48.0 bits (109), Expect = 1e-04
Identities = 26/69 (37%), Positives = 41/69 (59%)
Frame = +1
Query: 352 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
K AD++VI AG+ +KPG TR L NA I+++I +I + + + +NPV+ +
Sbjct: 70 KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVD---VL 126
Query: 532 ASEVLGKSG 558
A VL +SG
Sbjct: 127 AELVLQESG 135
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 48.0 bits (109), Expect = 1e-04
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 2/114 (1%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L LV + +YD+ P+ DL H +S +AA++DA
Sbjct: 12 VGGETAFLSAALGLVDEIVVYDVYEPLLRAQVLDLQHTGIDVAISTE------TAAMRDA 65
Query: 361 DVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 519
D+ V AG PR P + TR DL N + + + + + P +++ +TNP+++
Sbjct: 66 DIFVFAAGTPRTPDIKTRADLLEANIPVAKRCS-ELLEGFPGVVIS-VTNPMDA 117
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 47.6 bits (108), Expect = 2e-04
Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L+ + +AL D+ A + G A DL H P+ V+ I D+
Sbjct: 12 VGSCAAFALQCGGIAREIALLDLNADLAGGHALDLLH-GAPS-VADQVITSGGYEHIPDS 69
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK--AIVAIITNPVNSTVPIA 534
DV+ I AG+ RKP +R DL N N + I S+ K AI +++NPV+ +A
Sbjct: 70 DVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVDILTYLA 129
Query: 535 SEVL 546
++ L
Sbjct: 130 AQRL 133
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 47.6 bits (108), Expect = 2e-04
Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 3/128 (2%)
Frame = +1
Query: 142 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSH--VNTPAKV 312
QRN +G A L + L + D+ G A DL+H + P
Sbjct: 3 QRNINRVALIGAGSVGSSYAFALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNPT 62
Query: 313 SGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIV 492
G + K+AD+V I AG +KPG TR DL N I + + + + I
Sbjct: 63 KTWYGNYD---DCKEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIF 119
Query: 493 AIITNPVN 516
I TNPV+
Sbjct: 120 LIATNPVD 127
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 47.2 bits (107), Expect = 3e-04
Identities = 23/51 (45%), Positives = 33/51 (64%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 510
AD+VVI AG + G TR D+ NA I +IA I + APKA++ +++NP
Sbjct: 71 ADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNP 121
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 47.2 bits (107), Expect = 3e-04
Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Frame = +1
Query: 259 VTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 438
+ GV +L P S G E S +D DV V G PRKPGM R DL N +
Sbjct: 89 ILQGVELELQDGAYPLLKSIKTGSNE-SILFQDVDVAVFIGGFPRKPGMERKDLLTINGN 147
Query: 439 IVRDIALSIAQNAPKAIVA-IITNPVNSTVPIASE 540
I + ++ A K + ++ NP N+ I +E
Sbjct: 148 IFKKQGQALDTVAKKTCKSLVVANPANTNCLILAE 182
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase -
Oceanobacillus iheyensis
Length = 321
Score = 47.2 bits (107), Expect = 3e-04
Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 1/128 (0%)
Frame = +1
Query: 136 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKV 312
TSQ+ +G A L + LA+ D+ A G DL+H A
Sbjct: 3 TSQQAVNRVVLIGGGSVGVSYAFALMNQGVTEELAIIDLDADKALGDVMDLNHGKAFAPS 62
Query: 313 SGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIV 492
+ E KDAD+V I AG ++ G TR DL N I ++I + + I
Sbjct: 63 LTNVWLGEYGDC-KDADIVCICAGANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIF 121
Query: 493 AIITNPVN 516
I TNPV+
Sbjct: 122 LIATNPVD 129
>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
sequence - Ostreococcus tauri
Length = 131
Score = 46.8 bits (106), Expect = 3e-04
Identities = 23/37 (62%), Positives = 25/37 (67%)
Frame = -1
Query: 374 MTTTSASLMAADSSSGPLWPLTLAGVFTWERSAATPG 264
M TTS S AA SS+ P +P T A VFT E SAATPG
Sbjct: 1 MITTSQSFSAAPSSASPAYPFTCAAVFTCETSAATPG 37
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 46.4 bits (105), Expect = 5e-04
Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +1
Query: 340 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAIITNPVN 516
+ A KDADV ++ PR PGM R DL N I +I + A P V ++ NP N
Sbjct: 77 AVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPAN 136
Query: 517 STVPIASEVLGKSG 558
+ IA + K G
Sbjct: 137 TNAYIAMKSAMKHG 150
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 46.0 bits (104), Expect = 6e-04
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 3/114 (2%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGV-AADLSHV--NTPAKVSGHKGPEELSAAIK 354
+G +A + N + L L DI A DL H + +K+ G E
Sbjct: 16 VGAAVAFDMVMNHVCDDLILIDINKEKSWAEATDLQHSLGYSGSKMRVKDGEYE---ECN 72
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
DAD+VVI A +P G TR D+ A I+ +I +I ++ I+ +ITNPV+
Sbjct: 73 DADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPVD 126
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/55 (38%), Positives = 32/55 (58%)
Frame = +1
Query: 352 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
K++D+V+ AG RK G +R++L N SI+ D A I + I+TNPV+
Sbjct: 68 KNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVD 122
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 3/114 (2%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSH-VN-TPAKVSGHKGPEELSAAIK 354
+G A + + L L DI G A DLSH +N T + + G E K
Sbjct: 16 VGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYE---DCK 72
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
D D+V+I AG KPG +R D +A I+ + + ++ I + +NPV+
Sbjct: 73 DMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVD 126
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/47 (42%), Positives = 31/47 (65%)
Frame = +1
Query: 409 RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLG 549
RDDL N+ I+RD+ +I + AP+A V +ITNP++ V + +V G
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMDVMVHLMLKVTG 189
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 44.4 bits (100), Expect = 0.002
Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 346 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI-VAIITNPVNS 519
A KDADV + +PRKPGM R DL N I + + A + V ++ NP N+
Sbjct: 79 AFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNT 137
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 44.4 bits (100), Expect = 0.002
Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 1/123 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L + T + + D+ P + DL+ + + G E + A
Sbjct: 15 VGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGSAEEAG---QA 71
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
D+VVI AG ++ G R L N +++ I + P A++ ++ NPV+ IA
Sbjct: 72 DIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVDILTHIAKT 131
Query: 541 VLG 549
+ G
Sbjct: 132 LSG 134
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Frame = +1
Query: 268 GVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 447
GVA +L P +SG + + A KD D ++ PRK GM R +L + N I +
Sbjct: 53 GVAMELVDCAFPL-LSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQ 111
Query: 448 DIALSIAQNA-PKAIVAIITNPVNSTVPIASEVLGK 552
+I ++A P + +I NP N+ + S L K
Sbjct: 112 IQGAAINEHAKPTCRILVIGNPANTNALVLSTQLTK 147
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 310 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI 489
V+G +++ A KD DV + PRK GM R DL N I +++ A K +
Sbjct: 46 VAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDV 105
Query: 490 -VAIITNPVNSTVPIA 534
V ++ NP N+ IA
Sbjct: 106 KVLVVGNPANTNCLIA 121
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 43.2 bits (97), Expect = 0.004
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMT-----RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 519
DADV++ AG P R L TNA++VR++ I + +A++ ITNP+++
Sbjct: 72 DADVIICAAGPSVLPSEKDEMPDRAGLARTNAAVVREVMAGITKYTKEAVIIFITNPLDT 131
Query: 520 TVPIASEVLGKS 555
V IA G S
Sbjct: 132 IVYIAENEFGYS 143
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 42.7 bits (96), Expect = 0.006
Identities = 22/64 (34%), Positives = 34/64 (53%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 537
ADVV+I AGV PG T SI++ I + P AI+ ++ NPV++ +A
Sbjct: 70 ADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVDTLTTLAQ 129
Query: 538 EVLG 549
++ G
Sbjct: 130 DIAG 133
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 41.1 bits (92), Expect = 0.017
Identities = 33/112 (29%), Positives = 48/112 (42%), Gaps = 1/112 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L L LA+ D+ T G DL+H P + +DA
Sbjct: 26 VGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHA-VPWSHHNTRVTVGTYEDCRDA 84
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
+V I AG +KPG TR DL N +I + I + + I + +NPV+
Sbjct: 85 AMVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVD 136
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 40.3 bits (90), Expect = 0.030
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Frame = +1
Query: 268 GVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 447
GV +L P ++G + + A KD D ++ PR PGM R DL NA I
Sbjct: 55 GVIMELEDCAFPL-LAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFT 113
Query: 448 DIALSIAQNAPKAI-VAIITNPVNSTVPIA 534
++ A + + V ++ NP N+ IA
Sbjct: 114 AQGKALNAVASRNVKVLVVGNPANTNAYIA 143
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 39.9 bits (89), Expect = 0.040
Identities = 16/38 (42%), Positives = 26/38 (68%)
Frame = +1
Query: 412 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 525
DDL + N S+ + +A ++ Q+AP A V + TNP++S V
Sbjct: 16 DDLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIV 53
>UniRef50_Q014D4 Cluster: Chromosome 08 contig 1, DNA sequence; n=3;
Eukaryota|Rep: Chromosome 08 contig 1, DNA sequence -
Ostreococcus tauri
Length = 1453
Score = 39.9 bits (89), Expect = 0.040
Identities = 35/128 (27%), Positives = 56/128 (43%)
Frame = -3
Query: 555 ALAEHFRGNRHCRVNRVCDDGHNSFGCILSNGQSNVTDNGSISVE*VITGHSRFTGYSCW 376
A EH RG+ + V+ V D H G S+ + ++ + E V+ H+R +
Sbjct: 10 ASLEHLRGDGNRGVHGVGYDVHQRVGTRTSDRFAERANDPGVDAEQVVPRHARLARHPGG 69
Query: 375 DDYNISIFDGC**LLRSLVAADLGWGVHVGKVGCDAGGHRRYVV*SQPGHQRILLQ*KGQ 196
DD ++ L S V A ++V +V H R VV S+ H R+ L + +
Sbjct: 70 DDDQVAPSQTRVQLGVSHVRAHFRSRINVRQVHPHPSDHGRDVVQSELSHARVRLDERRE 129
Query: 195 RLADTTGG 172
RL D + G
Sbjct: 130 RLTDPSRG 137
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 39.9 bits (89), Expect = 0.040
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 1/123 (0%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G LA L + T + L D + G DLS T G + + A
Sbjct: 18 VGATLAYTLILQSICTEVLLVDPKTSLLDGQVRDLSDA-TSRSTKVRSGTHQEAG---QA 73
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 540
D+VVI AG +K G +R L N +I+ I S+ + ++ ++ NPV+ V A
Sbjct: 74 DIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVDILVYFARM 133
Query: 541 VLG 549
+ G
Sbjct: 134 MSG 136
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 39.5 bits (88), Expect = 0.053
Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Frame = +1
Query: 325 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAII 501
G +L A +D DV + P+KP D F NASI + +++ A P V +I
Sbjct: 69 GTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFAKPTVKVLVI 128
Query: 502 TNPVNSTVPIA 534
P N+ +A
Sbjct: 129 GMPTNTNALVA 139
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 39.1 bits (87), Expect = 0.069
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Frame = +1
Query: 223 LVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 399
L++ + + DI G A D SH + A K DA ++VI AG KP
Sbjct: 29 LLSEVVIIDINDNKAKGEALDASHTTSFAYSPNVKVRAGNYEDCADAQIIVITAGPSLKP 88
Query: 400 GMTRDDLF--NTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
D L +TN + I +I + AI+ ++TNPV+
Sbjct: 89 DDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVD 129
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 283
Score = 38.3 bits (85), Expect = 0.12
Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 3/114 (2%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSH-VNTPAKVSGHKGPEELSAAIKD 357
IG +A + L L+DI+ P+ D+ H ++ P + A +KD
Sbjct: 12 IGGEVAYVSALRKFADELVLFDISEPLQHAQKLDIIHGMDIPVSTN--------PADLKD 63
Query: 358 ADVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
AD + AG R P + TR DLF+ N I ++ + + + K IV +TNP++
Sbjct: 64 ADYCIFSAGYSRSPNIKTRADLFDKNLPIAKESSELLKGFSGKLIV--VTNPMD 115
>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
genitalium
Length = 312
Score = 38.3 bits (85), Expect = 0.12
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKP-GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
+KD D + I AG P+K G TR L N I++ IA I ++ + I +NPV+
Sbjct: 69 LKDYDFIFISAGRPQKQGGETRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPVD 125
>UniRef50_O34358 Cluster: Probable serine protease do-like htrA;
n=1; Bacillus subtilis|Rep: Probable serine protease
do-like htrA - Bacillus subtilis
Length = 449
Score = 38.3 bits (85), Expect = 0.12
Identities = 28/91 (30%), Positives = 41/91 (45%)
Frame = +1
Query: 280 DLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 459
DLS T VSG +S + + + VI PG + L NT+ IV ++
Sbjct: 248 DLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSM 307
Query: 460 SIAQNAPKAIVAIITNPVNSTVPIASEVLGK 552
I+++ + I I P N PIA E+L K
Sbjct: 308 KISEDDVEGIGFAI--PSNDVKPIAEELLSK 336
>UniRef50_UPI00015974E8 Cluster: HtrA; n=1; Bacillus
amyloliquefaciens FZB42|Rep: HtrA - Bacillus
amyloliquefaciens FZB42
Length = 450
Score = 37.9 bits (84), Expect = 0.16
Identities = 27/91 (29%), Positives = 42/91 (46%)
Frame = +1
Query: 280 DLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 459
DLS T VSG +S + ++ + VI PG + L NT+ I+ ++
Sbjct: 249 DLSRTVTQGIVSGLNRTVSISTSAGESSINVIQTDAAINPGNSGGPLLNTDGKIIGINSM 308
Query: 460 SIAQNAPKAIVAIITNPVNSTVPIASEVLGK 552
I+++ + I I P N PIA E+L K
Sbjct: 309 KISESDVEGIGFAI--PSNDVKPIAEELLTK 337
>UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 492
Score = 37.5 bits (83), Expect = 0.21
Identities = 19/75 (25%), Positives = 37/75 (49%)
Frame = +1
Query: 331 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 510
++LS A+ D D VV G +D+ S ++D+ LSI +N ++ +P
Sbjct: 173 DDLSLAVADCDGVVYVNGPDTSEISNENDIERLFVSSIQDVFLSIKRNGKSVRRVVLISP 232
Query: 511 VNSTVPIASEVLGKS 555
+S P+ + ++ K+
Sbjct: 233 ASSIFPVETTLVAKT 247
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 37.5 bits (83), Expect = 0.21
Identities = 36/124 (29%), Positives = 49/124 (39%), Gaps = 4/124 (3%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G A L + L L D A G DLS A + SA ++A
Sbjct: 18 VGAAAAYALVLGSIADELLLVDTRAAWRDGQVRDLSD----AAYASRSKTRVYSATYREA 73
Query: 361 ---DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 531
D+VVI AG G T D N SIVR I + ++ I+ NPV+ +
Sbjct: 74 SQCDIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPVDLMTSL 133
Query: 532 ASEV 543
A E+
Sbjct: 134 AKEL 137
>UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
gallisepticum|Rep: L-lactate dehydrogenase - Mycoplasma
gallisepticum
Length = 323
Score = 36.7 bits (81), Expect = 0.37
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKPGMT------RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 510
+KDADVV I A +P P R L N I+ +IAL + + K + I TNP
Sbjct: 68 LKDADVVAITASIPTVPTADGEVFTDRLQLMTANVKILNEIALELKRVGFKGLSIIPTNP 127
Query: 511 VNSTVPIASEVLG 549
+ + +V G
Sbjct: 128 CDVMAGVYQKVTG 140
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 36.3 bits (80), Expect = 0.49
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
Frame = +1
Query: 337 LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI--VRDIALSIAQNAPKAIVAIITNP 510
L+ A D + VPR PGM R DL N I ++ AL+ A A + ++ NP
Sbjct: 76 LNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR-DAKIFVVGNP 134
Query: 511 VNSTVPIA 534
VN+ IA
Sbjct: 135 VNTNCWIA 142
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 35.9 bits (79), Expect = 0.65
Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 1/108 (0%)
Frame = +1
Query: 196 LALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVV 372
+A+L K+ L + L D+ + A D+SH G ++ S A +DA V V
Sbjct: 49 IAILFKR--LASELVFIDVNEELAKAEAEDISHGAAFLGNPKIIGTKDYSLA-RDATVCV 105
Query: 373 IPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
I G L N +I +D+ + + AP +I+ I+T PV+
Sbjct: 106 ITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLIVTAPVD 153
>UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finger
protein 160, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to Zinc finger protein 160, partial -
Ornithorhynchus anatinus
Length = 912
Score = 35.5 bits (78), Expect = 0.85
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +3
Query: 198 GPSTEAESSGDQAGFIRHSACDPRRRSRPFPREHPSQGQRPQG 326
GP S G G +R+SA DP RRS P P +R +G
Sbjct: 143 GPGEPVRSGGAGEGAVRNSALDPTRRSHPSPIPPRGSRERDEG 185
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 35.5 bits (78), Expect = 0.85
Identities = 34/128 (26%), Positives = 62/128 (48%), Gaps = 9/128 (7%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHK--GPEELSAAIK 354
IG LA ++ + L + L+D P G A D+ H P S G E++ IK
Sbjct: 17 IGCALAHMICEKNLGD-VVLHDFRKDLPKGRALDILHTR-PLNRSRINILGTNEITD-IK 73
Query: 355 DADVVVIPAGVPRKPGMTRDD------LFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
D+ VVV+ V + D+ ++ +N +++++A S+ ++ P+A V + T+PV+
Sbjct: 74 DSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVVVTTSPVD 133
Query: 517 STVPIASE 540
+ E
Sbjct: 134 CMAKVLQE 141
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 35.1 bits (77), Expect = 1.1
Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Frame = +1
Query: 328 PEELSAAIKDADVVVIPAGVPR-KPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 504
P L KDADVVVI A +P K R L NA +++ A + K IV +
Sbjct: 62 PGTLLEDSKDADVVVITASIPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAA 121
Query: 505 NP 510
NP
Sbjct: 122 NP 123
>UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n=2;
Danio rerio|Rep: UPI0000D8BD94 UniRef100 entry - Danio
rerio
Length = 732
Score = 34.3 bits (75), Expect = 2.0
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 4/116 (3%)
Frame = +1
Query: 187 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK---GPEELSAAIKD 357
G P A+LL NP T+L + P+ H N A+++GH + S +
Sbjct: 285 GMPNAVLLSSNPNQTQLNQLTLNPLQLN-----HHPNCSAQLTGHPLTLPRPKFSYMNTN 339
Query: 358 ADVVVIPAGVPRKPGMTRDDLFN-TNASIVRDIALSIAQNAPKAIVAIITNPVNST 522
V+ G + + D FN TN ++ ++ I+ PK ++ PVN T
Sbjct: 340 GSAAVVFLGYTAMENLLKADFFNATNDTVNTMMSSVISVTLPKTTNTALSKPVNFT 395
>UniRef50_Q54IK5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 601
Score = 34.3 bits (75), Expect = 2.0
Identities = 22/65 (33%), Positives = 33/65 (50%)
Frame = -1
Query: 419 RSSRVIPGLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFTWERSAATPGVTGAMSYK 240
RSS +IP + G+ + + TT+ + + S S P P T S+ G TG+ SY
Sbjct: 524 RSSALIPSINGSSSEIPTTTTTTTTSLSISSPPTPTIPLSPAT---SSGNSGSTGSFSYI 580
Query: 239 ASLVT 225
SL+T
Sbjct: 581 GSLLT 585
>UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 488
Score = 34.3 bits (75), Expect = 2.0
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = -1
Query: 113 FCTARAAGFRARENIFVVC-LTCIYVYI*TIST*PSRP 3
FC+ R F R +F+ C LTC+Y + IST P+ P
Sbjct: 320 FCSKRIKNFGMRPTMFIGCFLTCLYCALVVISTPPTAP 357
>UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 258
Score = 33.9 bits (74), Expect = 2.6
Identities = 20/41 (48%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Frame = +3
Query: 216 ESSGDQAGFIRHSACDPRRRSRPFPRE-HPSQGQRPQGT*G 335
E GDQ RH AC R S P E P GQRP GT G
Sbjct: 6 EGRGDQERTRRHRACPGCRGSEVSPGEGAPGSGQRPAGTSG 46
>UniRef50_UPI000049A32B Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 1054
Score = 33.9 bits (74), Expect = 2.6
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Frame = -3
Query: 546 EHFRGNRHCRVNRVCDDGHNS---FGCILSNGQSNVTDN 439
E F N HC N C DG+N+ F C+ S+ + + DN
Sbjct: 458 ECFSYNNHCLTNCKCQDGYNATSLFSCVTSSCGNGINDN 496
>UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 321
Score = 33.9 bits (74), Expect = 2.6
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 6/69 (8%)
Frame = +1
Query: 349 IKDADVVVIPAG----VPRKP--GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 510
+ +ADV+++ AG P G R +L TN I+R I A + I +NP
Sbjct: 72 LSNADVIIMTAGPSIDASNGPATGAARRELAATNGKIIRSTMTQITSRNHDAAIIICSNP 131
Query: 511 VNSTVPIAS 537
+++ V IAS
Sbjct: 132 LDALVHIAS 140
>UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14749, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 778
Score = 33.5 bits (73), Expect = 3.4
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +3
Query: 159 GGRWCRRWYRPAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPREH 299
G R R + P GP E G Q +RH A P RR R P +H
Sbjct: 554 GVRAPRGLHHPGAGPQRAHEGRGRQPAAVRHPAEPPGRRHRERPGDH 600
>UniRef50_A7K8Q9 Cluster: Putative uncharacterized protein z299L;
n=1; Chlorella virus ATCV-1|Rep: Putative
uncharacterized protein z299L - Chlorella virus ATCV-1
Length = 159
Score = 33.5 bits (73), Expect = 3.4
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 6/56 (10%)
Frame = -3
Query: 552 LAEHFRGNRHCRVNRVC------DDGHNSFGCILSNGQSNVTDNGSISVE*VITGH 403
LA+H + N HCR+ +VC DDGH G G TD S ++ V+ GH
Sbjct: 69 LAQHEKSNTHCRI-QVCRDKPENDDGHRK-GHSKPKGDEPETDFVSFGLQQVVVGH 122
>UniRef50_Q608X6 Cluster: Hydrophobe/amphiphile Efflux-1 (HAE1)
family protein; n=17; Proteobacteria|Rep:
Hydrophobe/amphiphile Efflux-1 (HAE1) family protein -
Methylococcus capsulatus
Length = 1054
Score = 33.5 bits (73), Expect = 3.4
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -1
Query: 377 GMTTTSASLMAADSSSGPLWPLTLAGVFTWERSAATPGVTGAMSYKASLV 228
G+T AS+ A +GP+ +TL + SA PG+TG M + +LV
Sbjct: 436 GLTPKEASIKAMSEMTGPVIGITLVLTAVFLPSAFLPGITGQMFRQFALV 485
>UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein
precursor; n=1; Anabaena variabilis ATCC 29413|Rep:
Putative uncharacterized protein precursor - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 303
Score = 33.5 bits (73), Expect = 3.4
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +1
Query: 370 VIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI-ITNPVNS 519
++P G P KP T D+ +T ++ + L +NA KAI+ + NPVN+
Sbjct: 116 LVPEG-PSKPNPTAQDIVSTLGNLNLNSILVTRENADKAIIEVSFANPVNT 165
>UniRef50_P83778 Cluster: Malate dehydrogenase, cytoplasmic; n=1;
Candida albicans|Rep: Malate dehydrogenase, cytoplasmic
- Candida albicans (Yeast)
Length = 51
Score = 33.5 bits (73), Expect = 3.4
Identities = 19/29 (65%), Positives = 21/29 (72%)
Frame = +1
Query: 226 VTRLALYDIAPVTPGVAADLSHVNTPAKV 312
VT LALYDI P GVAAD+SHV T + V
Sbjct: 1 VTDLALYDIRP---GVAADVSHVPTNSTV 26
>UniRef50_UPI0000D9F76A Cluster: PREDICTED: hypothetical protein,
partial; n=2; Macaca mulatta|Rep: PREDICTED:
hypothetical protein, partial - Macaca mulatta
Length = 517
Score = 33.1 bits (72), Expect = 4.6
Identities = 24/110 (21%), Positives = 43/110 (39%), Gaps = 1/110 (0%)
Frame = +1
Query: 220 PLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 399
P+ + + A PG D + TP +SA+++ ++ P + P
Sbjct: 183 PVTGEVTITTAAGEVPGRDKDDADATTPIATETATVATTISASVEPTTIMTSPQPLGEAP 242
Query: 400 GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP-VNSTVPIASEVL 546
G +DD + + + A + +AP IT P ST + EV+
Sbjct: 243 GRDKDD-SDATTPVATETATATTIDAPVEPTTTITTPQPASTAAVTDEVV 291
>UniRef50_Q01UG3 Cluster: Putative uncharacterized protein precursor;
n=3; Solibacter usitatus Ellin6076|Rep: Putative
uncharacterized protein precursor - Solibacter usitatus
(strain Ellin6076)
Length = 1185
Score = 33.1 bits (72), Expect = 4.6
Identities = 28/81 (34%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Frame = -1
Query: 461 DKAMSRTMEALVLNRSSRVIPGLRGTPAGMTTTSASLMAADSSSGPLWPL-TLAGVFTWE 285
D A++ M A V N ++P GTPAG TTT A L+A P +PL +G F+
Sbjct: 887 DTALNTAMSASVANPFFGLVP--TGTPAGATTTVAQLLA----KYPEFPLGYTSGGFSGS 940
Query: 284 RSAATPGVTGAMSYKASLVTR 222
+ SY SL R
Sbjct: 941 GGVLEQNLNAGSSYFHSLNVR 961
>UniRef50_Q4D3U5 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 636
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Frame = -1
Query: 413 SRVIPGLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVF--TWERSAATPGVTGAMSYK 240
S V+P R A T+ + ++ GP PLT G + RSA PG + ++S +
Sbjct: 323 SAVLPRARRKSASQHTSHVLVTGTSATLGPPSPLTSTGTLPASLRRSATGPGASQSISRR 382
Query: 239 ASLVTR 222
A+ +R
Sbjct: 383 AAFTSR 388
>UniRef50_A2R1L8 Cluster: Contig An13c0060, complete genome; n=2;
Aspergillus|Rep: Contig An13c0060, complete genome -
Aspergillus niger
Length = 332
Score = 33.1 bits (72), Expect = 4.6
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 196 LALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVI 375
L +L ++ L + +IA + PGVA L ++ ++ +E+ +D DV+V
Sbjct: 51 LIILASRDILKAQQTAQEIANIAPGVATRLLELDLRSQAQVRNAAKEVLTYKEDIDVLVN 110
Query: 376 PAGVPRKP-GMTRDDL 420
AGV P +T D +
Sbjct: 111 NAGVMASPFSLTEDGI 126
>UniRef50_O26630 Cluster: UDP-N-acetylmuramyl tripeptide synthetase
related protein; n=1; Methanothermobacter
thermautotrophicus str. Delta H|Rep: UDP-N-acetylmuramyl
tripeptide synthetase related protein - Methanobacterium
thermoautotrophicum
Length = 682
Score = 33.1 bits (72), Expect = 4.6
Identities = 18/30 (60%), Positives = 21/30 (70%)
Frame = +1
Query: 292 VNTPAKVSGHKGPEELSAAIKDADVVVIPA 381
VNT A SG G E++A +KDAD VVIPA
Sbjct: 584 VNTVASESGIDGDREIAAILKDAD-VVIPA 612
>UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3;
Lactococcus lactis|Rep: L-lactate dehydrogenase 3 -
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Length = 323
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Frame = +1
Query: 349 IKDADVVVIPAGVPRKP-GMTRD--DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 519
+ DAD+VV+ A P G D L ++RDI I + +NPV+
Sbjct: 72 VSDADIVVLSANAPSATFGKNPDRLQLLENKVEMIRDITRKTMDAGFDGIFLVASNPVDV 131
Query: 520 TVPIASEVLG 549
+ +EV G
Sbjct: 132 LAQVVAEVSG 141
>UniRef50_Q6NPB9 Cluster: AT22132p; n=2; Drosophila
melanogaster|Rep: AT22132p - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 32.7 bits (71), Expect = 6.0
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 3/114 (2%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDA 360
+G ++ +L L L + DI + A D H + P S KD+
Sbjct: 59 VGTAISAMLLLRNLTKNLVILDINYELAKAEALDFQHASAFLS-DARVVPCGDSTNSKDS 117
Query: 361 DVVVIPAGVPRKPGMTRDDL--FNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
DVV+I AG R G R L I++ + + +P A II+NP +
Sbjct: 118 DVVIITAGA-RPSGKDRSRLAAMQKTVEILKKAVPKLVELSPNATFIIISNPAD 170
>UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 303
Score = 32.7 bits (71), Expect = 6.0
Identities = 25/111 (22%), Positives = 52/111 (46%)
Frame = +1
Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDAD 363
+G +A L N L L + G + D++ +G ++ S I +D
Sbjct: 13 VGASIAFLCVSNGLDDVLLVNTTKEKAIGESLDVASAIPANSKFSIRGTDDYSELI-GSD 71
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 516
+V+I A V +++ + +++++IA I + P AIV +++NP++
Sbjct: 72 IVIIAASVGIYTKHRAENI-DHQVAMIKNIAKKIKKYCPSAIVLLVSNPLD 121
>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
domain-containing histone demethylation protein 1B -
Homo sapiens (Human)
Length = 1336
Score = 32.7 bits (71), Expect = 6.0
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -2
Query: 166 RPPL*SSSVMWWKSSLHHFVQQ 101
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
>UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG02077.1 - Gibberella zeae PH-1
Length = 184
Score = 32.3 bits (70), Expect = 8.0
Identities = 15/40 (37%), Positives = 22/40 (55%)
Frame = +1
Query: 229 TRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAA 348
T A +AP+ P AA+ +TPA + KGPE+ + A
Sbjct: 126 TAAATTTVAPIIPTTAAEEPATSTPAAATPTKGPEQANGA 165
>UniRef50_Q8XN38 Cluster: Probable hexosyltransferase; n=1;
Clostridium perfringens|Rep: Probable hexosyltransferase
- Clostridium perfringens
Length = 409
Score = 32.3 bits (70), Expect = 8.0
Identities = 15/34 (44%), Positives = 20/34 (58%)
Frame = +1
Query: 280 DLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPA 381
D S ++T K G PEEL DADV++IP+
Sbjct: 277 DSSEIDTRIKYLGKLNPEELKQQYIDADVLIIPS 310
>UniRef50_Q7NV30 Cluster: Probable colicin V production protein;
n=1; Chromobacterium violaceum|Rep: Probable colicin V
production protein - Chromobacterium violaceum
Length = 172
Score = 32.3 bits (70), Expect = 8.0
Identities = 20/83 (24%), Positives = 42/83 (50%)
Frame = -1
Query: 560 TPLLPSTSEAIGTVELTGFVMMATIALGAF*AMDKAMSRTMEALVLNRSSRVIPGLRGTP 381
T LPS+ ++ G + GFV++ + A + ++ ++++ L +R++ G+ G
Sbjct: 49 TDFLPSSLQSEGLRMVAGFVLVFFLVWLATALLRVTLTGLVDSIGLGAINRLLGGVFGLA 108
Query: 380 AGMTTTSASLMAADSSSGPLWPL 312
GM +A ++ SS P P+
Sbjct: 109 RGMVLVTALVLLGGLSSLPQKPM 131
>UniRef50_A3PZC4 Cluster: Cytochrome oxidase assembly; n=22;
Corynebacterineae|Rep: Cytochrome oxidase assembly -
Mycobacterium sp. (strain JLS)
Length = 342
Score = 32.3 bits (70), Expect = 8.0
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Frame = -1
Query: 386 TPAGMTTTSASLMAADSSSG-PLWPLTLAGVFTWERSAATPGVTGAMSYKASLVT 225
T G++ T A + S G P WP G FT A PG+ A+ + L+T
Sbjct: 32 TQGGISVTGAIVRVTASGLGCPTWPQCFPGSFTPVPHAEVPGIHQAVEFGNRLIT 86
>UniRef50_A7SI71 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1647
Score = 32.3 bits (70), Expect = 8.0
Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = -1
Query: 392 RGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFTWERSAATPGVTGAMS-YKASLVT 225
RG P+GM+TT++S ++D S L +T G S+ TPG GA++ SLVT
Sbjct: 931 RGLPSGMSTTNSSTQSSDPS--VLGSVTSVGNLV--TSSLTPGFLGALAELVRSLVT 983
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.315 0.131 0.361
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 598,105,585
Number of Sequences: 1657284
Number of extensions: 13156788
Number of successful extensions: 41763
Number of sequences better than 10.0: 164
Number of HSP's better than 10.0 without gapping: 39607
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 41677
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 37488397230
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
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