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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Nnor0116
         (706 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k...   260   3e-68
UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi...   242   5e-63
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu...   242   5e-63
UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py...   198   8e-50
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R...   193   4e-48
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...   176   4e-43
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ...   168   1e-40
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6...   162   9e-39
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re...   157   3e-37
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...   152   7e-36
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof...   150   3e-35
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ...   147   3e-34
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis...   146   5e-34
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P...   145   8e-34
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep...   145   1e-33
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep...   141   1e-32
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis...   140   4e-32
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P...   138   9e-32
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol...   138   1e-31
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla...   136   4e-31
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis...   135   9e-31
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale...   133   5e-30
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R...   131   2e-29
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R...   130   2e-29
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (...   130   3e-29
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|...   129   6e-29
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea...   129   8e-29
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran...   128   1e-28
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ...   127   2e-28
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr...   126   5e-28
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact...   123   5e-27
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac...   122   7e-27
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|...   122   9e-27
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube...   121   2e-26
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ...   120   3e-26
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce...   120   5e-26
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R...   118   1e-25
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py...   118   1e-25
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|...   118   1e-25
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte...   118   2e-25
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism...   117   2e-25
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re...   116   6e-25
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr...   115   1e-24
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr...   115   1e-24
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R...   115   1e-24
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ...   114   2e-24
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte...   114   2e-24
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py...   114   2e-24
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k...   113   3e-24
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P...   113   4e-24
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ...   113   4e-24
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n...   113   5e-24
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis...   112   7e-24
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...   112   9e-24
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc...   111   1e-23
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re...   111   2e-23
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan...   111   2e-23
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,...   110   3e-23
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ...   109   5e-23
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re...   109   5e-23
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=...   109   9e-23
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|...   108   2e-22
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R...   107   3e-22
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme...   107   3e-22
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep...   106   6e-22
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba...   105   1e-21
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep...   105   1e-21
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis...   105   1e-21
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ...   105   1e-21
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re...   104   2e-21
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae...   103   3e-21
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c...   103   3e-21
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci...   103   4e-21
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep...   102   1e-20
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp....   101   1e-20
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett...   100   3e-20
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop...   100   4e-20
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran...   100   4e-20
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc...   100   7e-20
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R...    98   2e-19
UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania brazil...    97   3e-19
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari...    96   6e-19
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact...    96   9e-19
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter...    96   9e-19
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P...    95   1e-18
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re...    95   1e-18
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ...    95   2e-18
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R...    93   6e-18
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism...    92   1e-17
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re...    92   1e-17
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|...    91   2e-17
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism...    89   7e-17
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A...    89   1e-16
UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate k...    89   1e-16
UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japon...    89   1e-16
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter...    88   2e-16
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf...    86   7e-16
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...    85   2e-15
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ...    84   3e-15
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ...    84   3e-15
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun...    84   4e-15
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace...    83   6e-15
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ...    83   9e-15
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m...    83   9e-15
UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wicker...    83   9e-15
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne...    82   1e-14
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep...    82   1e-14
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re...    82   1e-14
UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; ...    81   2e-14
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba...    81   2e-14
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae...    81   2e-14
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae...    81   3e-14
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno...    81   3e-14
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ...    80   5e-14
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr...    80   6e-14
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P...    80   6e-14
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae...    78   2e-13
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P...    78   2e-13
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m...    74   3e-12
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr...    74   4e-12
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales...    73   5e-12
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:...    73   5e-12
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py...    72   2e-11
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno...    70   6e-11
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty...    66   8e-10
UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep...    64   3e-09
UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri...    64   3e-09
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ...    64   4e-09
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w...    62   1e-08
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:...    62   1e-08
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R...    62   2e-08
UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...    59   1e-07
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola...    58   2e-07
UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;...    57   5e-07
UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae...    54   5e-06
UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|...    54   5e-06
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende...    53   8e-06
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum...    52   1e-05
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...    50   7e-05
UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije...    49   1e-04
UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k...    48   3e-04
UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter...    47   5e-04
UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi...    47   5e-04
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep...    45   0.002
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ...    44   0.005
UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267, w...    43   0.008
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ...    42   0.015
UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vaden...    42   0.015
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua...    42   0.020
UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; ...    42   0.020
UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R...    42   0.020
UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinel...    41   0.034
UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden...    40   0.045
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten...    40   0.045
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz...    40   0.060
UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep...    40   0.079
UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep: CG1222...    40   0.079
UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej...    39   0.14 
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali...    37   0.42 
UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_0023...    37   0.55 
UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr...    36   0.97 
UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium c...    36   1.3  
UniRef50_UPI0000DB7164 Cluster: PREDICTED: similar to CG31559-PA...    35   1.7  
UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R...    35   1.7  
UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor, ...    35   1.7  
UniRef50_A3CQV6 Cluster: Conserved uncharacterized protein; n=9;...    35   2.2  
UniRef50_Q89VQ2 Cluster: ABC transporter peptide-binding protein...    34   3.0  
UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding...    34   3.0  
UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3; ...    34   3.0  
UniRef50_A3CLR6 Cluster: Fibril-like structure subunit FibA, put...    33   5.2  
UniRef50_Q58MH8 Cluster: Putative uncharacterized protein; n=1; ...    33   5.2  
UniRef50_Q8EYH8 Cluster: MutS-like mismatch repair protein, ATPa...    33   6.8  
UniRef50_Q2AHN9 Cluster: Radical SAM; n=1; Halothermothrix oreni...    33   6.8  
UniRef50_Q3EBL2 Cluster: Uncharacterized protein At2g37440.1; n=...    33   6.8  
UniRef50_Q46513 Cluster: ORF 2 gene product; n=1; Desulfurococcu...    33   9.0  

>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
           kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to Pyruvate kinase (PK) - Tribolium castaneum
          Length = 557

 Score =  260 bits (636), Expect = 3e-68
 Identities = 121/199 (60%), Positives = 151/199 (75%)
 Frame = +1

Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288
           +QL H   LDI S    +RL+GIICT+GP++ +V  LE+M+E GMN+AR+  SHG+ E H
Sbjct: 32  TQLDHNSLLDIQSHPPQVRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMH 91

Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468
            E I+N R A ++YS +LG  + L++ALD KGPE+RTG +EGG +AEVELKKGE IKLTT
Sbjct: 92  TELIQNVRTAVENYSKRLGVMYPLSLALDIKGPEVRTGYMEGGIAAEVELKKGEQIKLTT 151

Query: 469 SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLG 648
              Y EKG++  IYVDY NI  VV+PGNRIF+DDGLIS+IC SV    LTC++ENGGMLG
Sbjct: 152 DKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLICTSVQGSVLTCSVENGGMLG 211

Query: 649 SRKGVNLPGIPVDLPAVSE 705
           S K VNLPGI +DLP VSE
Sbjct: 212 SCKNVNLPGIDIDLPVVSE 230


>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
           nigroviridis|Rep: Pyruvate kinase - Tetraodon
           nigroviridis (Green puffer)
          Length = 569

 Score =  242 bits (593), Expect = 5e-63
 Identities = 119/204 (58%), Positives = 153/204 (75%), Gaps = 7/204 (3%)
 Frame = +1

Query: 115 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 294
           L+HMC LDIDS  +  R +GIICTIGPASR+V +L++M+++GMN+AR+NFSHG+HEYHAE
Sbjct: 25  LEHMCLLDIDSAPTTARNTGIICTIGPASRSVGMLKEMIKSGMNIARLNFSHGTHEYHAE 84

Query: 295 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSP 474
           TI+N REA +S+         + IALDTKGPEIRTGL+ G G+AEVELKKG  IK+T   
Sbjct: 85  TIKNVREACESFEPGSIQYRPIGIALDTKGPEIRTGLIHGSGTAEVELKKGNVIKITLDD 144

Query: 475 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-------SADTLTCTIEN 633
            Y EK + + +++DYKNIT VV  G++I+IDDGLIS+  + +        +D L C IEN
Sbjct: 145 AYVEKCSEEILWLDYKNITKVVDVGSKIYIDDGLISLQVKEIGNSSISSGSDYLMCEIEN 204

Query: 634 GGMLGSRKGVNLPGIPVDLPAVSE 705
           GG LGS+KGVNLPG  VDLPAVS+
Sbjct: 205 GGTLGSKKGVNLPGAAVDLPAVSD 228


>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
           Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
           Homo sapiens (Human)
          Length = 574

 Score =  242 bits (593), Expect = 5e-63
 Identities = 117/200 (58%), Positives = 152/200 (76%), Gaps = 3/200 (1%)
 Frame = +1

Query: 115 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 294
           L+H+C LDIDS+    R + II TIGPASR+V  L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70  LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129

Query: 295 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 465
           +I N REA +S++   GSP S   +AIALDTKGPEIRTG+L+GG  +EVEL KG  + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186

Query: 466 TSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 645
             P ++ +GNA+T++VDY NI  VV  G RI+IDDGLIS++ Q +  + L   +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246

Query: 646 GSRKGVNLPGIPVDLPAVSE 705
           GSRKGVNLPG  VDLP +SE
Sbjct: 247 GSRKGVNLPGAQVDLPGLSE 266


>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 744

 Score =  198 bits (484), Expect = 8e-50
 Identities = 90/156 (57%), Positives = 115/156 (73%), Gaps = 1/156 (0%)
 Frame = +1

Query: 241 MNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGG 420
           M V RMNFSHGSHEYH +TI+  R+A   Y  + G P +LAIALDTKGPEIRTG L GG 
Sbjct: 1   MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGN 60

Query: 421 S-AEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 597
             AE+ELK G+ + L+T  +  +K N D IYVDY+ +  +VKPGNR+F+DDGLI++I + 
Sbjct: 61  DRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKE 120

Query: 598 VSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
              D + C +ENGG LGS KG+NLPG+PVDLP+V+E
Sbjct: 121 SKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTE 156


>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
           Pyruvate kinase - Leishmania mexicana
          Length = 499

 Score =  193 bits (470), Expect = 4e-48
 Identities = 99/199 (49%), Positives = 135/199 (67%), Gaps = 1/199 (0%)
 Frame = +1

Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288
           SQL H   L I    +  R + IICTIGP++++V  L+ ++++GM+VARMNFSHGSHEYH
Sbjct: 2   SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYH 61

Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468
             TI N R+A    +A+LG   ++AIALDTKGPEIRTG   GG   +  +++G T  +TT
Sbjct: 62  QTTINNVRQA----AAELG--VNIAIALDTKGPEIRTGQFVGG---DAVMERGATCYVTT 112

Query: 469 SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS-VSADTLTCTIENGGML 645
            P + +KG  D  Y+DY+N++ VV+PGN I+IDDG++ +  QS     TL CT+ N   +
Sbjct: 113 DPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTI 172

Query: 646 GSRKGVNLPGIPVDLPAVS 702
             R+GVNLPG  VDLPAVS
Sbjct: 173 SDRRGVNLPGCDVDLPAVS 191


>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 554

 Score =  176 bits (429), Expect = 4e-43
 Identities = 88/207 (42%), Positives = 130/207 (62%)
 Frame = +1

Query: 85  KPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNF 264
           K  +    +QL H+C LD+  ++S+ RL  +I TI  +SRN   +  M+  G+N+ R+NF
Sbjct: 6   KSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNF 65

Query: 265 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 444
           SH SHE H++TI    EA +    + G   ++AIA DT+GP+IRTGLL+G    +V L+ 
Sbjct: 66  SHESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRS 121

Query: 445 GETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 624
           G+ ++L+ + D  +KGN + +YVDY NI N+ K G+R+FIDDG + +    V  D L C 
Sbjct: 122 GDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCE 181

Query: 625 IENGGMLGSRKGVNLPGIPVDLPAVSE 705
           + +GG L +   V LP I +DLPAVSE
Sbjct: 182 VIHGGQLNNNCNVILPEIEIDLPAVSE 208


>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
           Pyruvate kinase - Neurospora crassa
          Length = 527

 Score =  168 bits (409), Expect = 1e-40
 Identities = 86/204 (42%), Positives = 128/204 (62%), Gaps = 2/204 (0%)
 Frame = +1

Query: 100 NVGSQLQHMCGLDIDSKSSY-IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGS 276
           ++G ++Q +  L+ + + +   R + IICTIGP + +V  + K+ + G+NV RMNFSHGS
Sbjct: 10  SLGGKIQWLAQLNTEFQPAREFRRTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGS 69

Query: 277 HEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 456
           +EYH   I N R+AEK +    G P  +AIALDTKGPEIRTG  +     ++ +  G  +
Sbjct: 70  YEYHQSVIDNARQAEKVHP---GRP--IAIALDTKGPEIRTGNTK--NDEDIPISAGTIL 122

Query: 457 KLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIEN 633
            +TT   Y+++   + +YVDY NIT V+ PG  I++DDG+++  + + V   T+     N
Sbjct: 123 NITTDEKYKDECTIEHMYVDYVNITKVIAPGRIIYVDDGVLAFEVLEIVDDKTIKVKARN 182

Query: 634 GGMLGSRKGVNLPGIPVDLPAVSE 705
            G + SRKGVNLP   VDLPA+SE
Sbjct: 183 NGYISSRKGVNLPNTDVDLPALSE 206


>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
           Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
           Glycine max (Soybean)
          Length = 511

 Score =  162 bits (393), Expect = 9e-39
 Identities = 83/179 (46%), Positives = 114/179 (63%), Gaps = 2/179 (1%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CT+GPASR+V + EK++  GMNVAR NFSHG+H+YH ET+ N +      +A   +  
Sbjct: 25  IVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLK------TAMHNTGI 78

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
             A+ LDTKGPEIRTG L+ G    ++LK+G+ + +TT  DY  KG+ + I + YK +  
Sbjct: 79  LCAVMLDTKGPEIRTGFLKDG--KPIQLKEGQEVTITT--DYDIKGDPEMISMSYKKLPV 134

Query: 535 VVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            +KPGN I   DG I++   S   D  T+ C  EN   LG RK VNLPG+ VDLP ++E
Sbjct: 135 HLKPGNTILCSDGTITLTVLSCDPDAGTVRCRCENTATLGERKNVNLPGVVVDLPTLTE 193


>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 510

 Score =  157 bits (380), Expect = 3e-37
 Identities = 84/179 (46%), Positives = 114/179 (63%), Gaps = 2/179 (1%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           IICT+GP SR+V ++EK+++ GMNVAR NFSHGSH YH ET+ N R A  +      +  
Sbjct: 20  IICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDN------TGI 73

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
             A+ LDTKGPEIRTG L+ G    ++L +G+  ++T S DY  +G+++ I + YK +  
Sbjct: 74  LSAVMLDTKGPEIRTGFLKEG--KPIQLNQGQ--EITISIDYMIEGDSNVISMSYKKLAE 129

Query: 535 VVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            VKPG+ I   DG IS+   S   S   + C  EN  +LG RK VNLPGI VDLP ++E
Sbjct: 130 DVKPGDVILCSDGTISLTVLSCDKSFGLVRCRCENSAILGERKNVNLPGIVVDLPTLTE 188


>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Leptospira interrogans
          Length = 486

 Score =  152 bits (369), Expect = 7e-36
 Identities = 78/186 (41%), Positives = 121/186 (65%)
 Frame = +1

Query: 145 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 324
           S+SS  R + IICTIGPA+ +  +++ + E GMNVAR+N SHG+H++H   IRN +   K
Sbjct: 3   SESSVFRKTKIICTIGPATSDKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNK 62

Query: 325 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADT 504
                L +P  +AI LDT+GPEIRTG L+      ++LK GET      P   E+    +
Sbjct: 63  DV---LKNP--IAILLDTQGPEIRTGDLQVD---HLDLKVGETFTFHIIPG--EESEEQS 112

Query: 505 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 684
           ++V+YK+I   +K G+ + +D+GLI+++ + ++   L C + +GG LGSRK +NLPGI V
Sbjct: 113 VFVNYKDIVKDLKVGDPVTVDNGLINLVVEEINDSALKCKVLDGGRLGSRKHINLPGIRV 172

Query: 685 DLPAVS 702
           +LP+++
Sbjct: 173 NLPSIT 178


>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
           aerofaciens ATCC 25986|Rep: Pyruvate kinase -
           Collinsella aerofaciens ATCC 25986
          Length = 486

 Score =  150 bits (364), Expect = 3e-35
 Identities = 76/178 (42%), Positives = 114/178 (64%), Gaps = 1/178 (0%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CT+GPA  +   + +M++ GMNVAR NFSHGS++ H   I   R   K    +LG P 
Sbjct: 7   IVCTMGPACDSDETIREMIKAGMNVARFNFSHGSYDEHHGRIERVRRISK----ELGLP- 61

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQE-KGNADTIYVDYKNIT 531
            + I LDTKGPE+RTGLL  G   +V +K G+ I +T  P  ++  G A+ I +DY  + 
Sbjct: 62  -VGILLDTKGPEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDFHGTAEHISLDYLALP 118

Query: 532 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           + V+ G+ I IDDGL+++  +SV    +TC ++N G++G RKGVN+P + + LPA++E
Sbjct: 119 SEVEKGSLILIDDGLVALEVESVDGQDMTCVVKNDGLIGERKGVNMPNVNISLPAITE 176


>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
           Pyruvate kinase I - Salmonella typhimurium
          Length = 470

 Score =  147 bits (356), Expect = 3e-34
 Identities = 77/177 (43%), Positives = 107/177 (60%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CTIGP + +  +L KM++ GMNV R+NFSHG +  H + I+N R       +K G   
Sbjct: 6   IVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNV----MSKTGK-- 59

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
             AI LDTKGPEIRT  LEGG   +V LK G+T   TT  D    GN + + V Y+  T+
Sbjct: 60  KAAILLDTKGPEIRTIKLEGGN--DVSLKAGQTFTFTT--DKSVVGNNEIVAVTYEGFTS 115

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            +  GN + +DDGLI +   ++  + + C + N G LG  KGVNLPG+ + LPA++E
Sbjct: 116 DLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAE 172


>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
           organisms|Rep: Pyruvate kinase - Eimeria tenella
          Length = 531

 Score =  146 bits (354), Expect = 5e-34
 Identities = 73/177 (41%), Positives = 107/177 (60%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CT+GP+  +V  + ++++ GMNV R+NFSHG HE H   ++N +EA K    K     
Sbjct: 60  IVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGK----- 114

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            +A+ LDTKGPEIRTG+LEG     +EL  G+ +K+ T  DY   GN   I   Y+ + +
Sbjct: 115 RVALLLDTKGPEIRTGMLEG--DKPIELHAGDMLKIVT--DYSFVGNKSCIACSYEKLPS 170

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            VKPGN I I DG +S+       D +   + N  ++G++K +NLPG+ VDLP + E
Sbjct: 171 SVKPGNTILIADGSLSVEVVECGKDYVMTRVMNPAIIGNKKNMNLPGVKVDLPVIGE 227


>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
           Pyruvate kinase - Bacillus subtilis
          Length = 585

 Score =  145 bits (352), Expect = 8e-34
 Identities = 83/184 (45%), Positives = 117/184 (63%), Gaps = 2/184 (1%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+CTIGPAS ++ +L K+ME+GMNVAR+NFSHG  E H   I+N REA K    K
Sbjct: 1   MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASK----K 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           LG   ++ I LDTKGPEIRT  +E GG   +EL+ G+  +L  S D +  G  D I V Y
Sbjct: 57  LGK--NVGILLDTKGPEIRTHTMENGG---IELETGK--ELIISMD-EVVGTTDKISVTY 108

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSA--DTLTCTIENGGMLGSRKGVNLPGIPVDLP 693
           + + + V+ G+ I +DDGLI +    V A    +   + N G L ++KGVN+PG+ V+LP
Sbjct: 109 EGLVHDVEQGSTILLDDGLIGLEVLDVDAAKREIKTKVLNNGTLKNKKGVNVPGVSVNLP 168

Query: 694 AVSE 705
            ++E
Sbjct: 169 GITE 172


>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
           Pyruvate kinase - Phaeodactylum tricornutum
          Length = 543

 Score =  145 bits (351), Expect = 1e-33
 Identities = 78/183 (42%), Positives = 111/183 (60%), Gaps = 2/183 (1%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CTIGPA  NV  LE ++E+GMNVAR NFSHG H  H   +   R+A ++     
Sbjct: 31  RRTKIVCTIGPACWNVDQLEILIESGMNVARFNFSHGDHAGHGAVLERVRQAAQNKGR-- 88

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
               ++AI LDTKGPEIRTG    G S ++EL KGETI LT+  DY+ KG+   +   Y 
Sbjct: 89  ----NIAILLDTKGPEIRTGFFANGAS-KIELVKGETIVLTS--DYKFKGDQHKLACSYP 141

Query: 523 NITNVVKPGNRIFIDDG--LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696
            +   V  G +I + DG  +++++    +A  ++C I+N   +G RK +NLPG+ VDLP 
Sbjct: 142 ALAQSVTQGQQILVADGSLVLTVLQTDEAAGEVSCRIDNNASMGERKNMNLPGVKVDLPT 201

Query: 697 VSE 705
            +E
Sbjct: 202 FTE 204


>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
           Pyruvate kinase - Clostridium phytofermentans ISDg
          Length = 580

 Score =  141 bits (342), Expect = 1e-32
 Identities = 75/182 (41%), Positives = 111/182 (60%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+CT+GPA+ + AVL ++M  GM+VAR NFSHG +E H       R      SA+
Sbjct: 1   MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRRL----SAE 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           L  P  +A  LDTKGPEIR G  E G   ++ELKKG+   LTT+      G+   + + Y
Sbjct: 57  LKLP--IATLLDTKGPEIRIGTFENG---KIELKKGQIFTLTTNDIV---GDETQVSITY 108

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
           KN+   +K G +I IDDGLI +   +++   + C + NGGM+ + KGVN+PG+ + +P +
Sbjct: 109 KNLIRDIKNGVKILIDDGLIELKVFNITDTDIICEVLNGGMISNHKGVNVPGVELSMPFI 168

Query: 700 SE 705
           S+
Sbjct: 169 SK 170


>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
           bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
           (Water mold)
          Length = 517

 Score =  140 bits (338), Expect = 4e-32
 Identities = 71/189 (37%), Positives = 114/189 (60%), Gaps = 3/189 (1%)
 Frame = +1

Query: 145 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 324
           SK+    ++ I+ T+GP S N    +++   G+ + R+NFSH +++     + + R ++ 
Sbjct: 23  SKNDAFSMTKIVGTVGPVSENAKTTQELTNAGLKIMRINFSHATYDEAHLRMSHLRASKG 82

Query: 325 SYSAKLGSPFSL-AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNAD 501
            ++   G  F++ A+ LDT+GPEIR G        ++ L KG+ I LTT   Y+E    D
Sbjct: 83  VHAKHTGKEFNVRAVLLDTQGPEIRGGAFP---EKKINLTKGDMITLTTDVQYKEASTKD 139

Query: 502 TIYVDYKNITNVVKPGNRIFIDDGLISIICQS--VSADTLTCTIENGGMLGSRKGVNLPG 675
            +YV Y+ +   VK G+ + +DDGLIS+  +S  V++  + C IEN  +LGSRKGVNLPG
Sbjct: 140 MLYVTYEQLPATVKVGDTVLLDDGLISLTVKSIDVASGQVRCLIENSEVLGSRKGVNLPG 199

Query: 676 IPVDLPAVS 702
           + VDLPA++
Sbjct: 200 LVVDLPALT 208


>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
           Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 506

 Score =  138 bits (335), Expect = 9e-32
 Identities = 75/199 (37%), Positives = 111/199 (55%), Gaps = 1/199 (0%)
 Frame = +1

Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288
           S+LQ +  L I +    +R + II TIGP + +   +  + + G+N+ R+NFSHGS+E+H
Sbjct: 4   SRLQRLANLKIGTPQQ-LRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFH 62

Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468
              I N  ++E+ +    G P  LAIALDTKGPEIRTG        ++ +     +  TT
Sbjct: 63  QSVIENAVKSEQQFP---GRP--LAIALDTKGPEIRTG--RTLNDQDLYIPVDHQMIFTT 115

Query: 469 SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 645
              +    N   +Y+DY N+T V+ PG  I++DDG++S  + Q +    L     N G +
Sbjct: 116 DASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYI 175

Query: 646 GSRKGVNLPGIPVDLPAVS 702
            S KGVNLP   VDLP +S
Sbjct: 176 ASHKGVNLPNTDVDLPPLS 194


>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
           Oligohymenophorea|Rep: Pyruvate kinase family protein -
           Tetrahymena thermophila SB210
          Length = 505

 Score =  138 bits (334), Expect = 1e-31
 Identities = 71/181 (39%), Positives = 107/181 (59%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CTIGP+  +   L +++E GMNVAR+NFSHG H  H ET+R  +EA K+     
Sbjct: 22  RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKA----- 76

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
                 A+ LDTKGPEIRTGL++      + L  G+ +++TT  DY   G+   +   YK
Sbjct: 77  RKNIQCALMLDTKGPEIRTGLVKDQTKKLINLVAGQELEITT--DYSVLGDEKVLACSYK 134

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           ++   VK G ++ I DG +  I + +  D++   ++N   +G +K +NLPG  VDLP V+
Sbjct: 135 SLPKSVKVGGQVLIADGTLVCIVKEIKQDSIIVNVQNTCSIGEKKNMNLPGAIVDLPTVT 194

Query: 703 E 705
           E
Sbjct: 195 E 195


>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
           Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
           annulata
          Length = 513

 Score =  136 bits (330), Expect = 4e-31
 Identities = 72/177 (40%), Positives = 106/177 (59%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CT+GPA  NV  + +M+++GMN+ R NFSHG+HE H +T+   +EA KS         
Sbjct: 42  IVCTMGPACGNVETIIQMVKSGMNICRFNFSHGNHETHTKTLNLVKEALKSVPEA----- 96

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
           ++ + LDTKGPEIRTG L+      + L++G T+K+TT  DY  +G+   I   YK +  
Sbjct: 97  NIGLMLDTKGPEIRTGFLK--NHTPITLEEGSTLKITT--DYTIEGDETIISCSYKKLPQ 152

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            VK GN I I DG +S    +V  D +   + N   +G  K +NLPG+ V+LP ++E
Sbjct: 153 SVKVGNIILIADGSLSCEVLAVFDDYIEVKVLNNAKIGEYKNMNLPGVKVELPVLTE 209


>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
           organisms|Rep: Pyruvate kinase - Vibrio cholerae
          Length = 470

 Score =  135 bits (327), Expect = 9e-31
 Identities = 75/177 (42%), Positives = 102/177 (57%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CTIGP + +V  L +++  GMNV R+NFSHG +  H   I N R+  +    +L    
Sbjct: 6   IVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQL---- 61

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
             AI LDTKGPEIRT  LE G   +V+L  G+    TT  D +  GN + + V Y     
Sbjct: 62  --AILLDTKGPEIRTIKLENGD--DVDLVAGQEFTFTT--DTKVVGNKERVAVTYSGFAK 115

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            +  GNRI +DDGLI +   + +   + C + N G LG  KGVNLPG+ V+LPA+SE
Sbjct: 116 DLNVGNRILVDDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLPALSE 172


>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
           Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
           sulfurreducens
          Length = 480

 Score =  133 bits (321), Expect = 5e-30
 Identities = 73/181 (40%), Positives = 110/181 (60%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + II T+GP S +  ++ ++M+ G++V R+NFSHGS++   E I   R      SA+ 
Sbjct: 6   RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVIAAIRRL----SAER 61

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G    + I  D +GP+IRTG +E G    + L +G+++ +TT       G   TIY   +
Sbjct: 62  GK--EIGILADLQGPKIRTGRMENGA---IPLVRGDSLDITTDEVLGRPGLISTIY---Q 113

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           ++ + VKPG+RI +DDGLI +  QSVS  T+ CT+  GGML   KG+NLPG+ V  P++S
Sbjct: 114 SLPHDVKPGSRILLDDGLIELRVQSVSGATVRCTVVQGGMLKDLKGINLPGVKVSAPSLS 173

Query: 703 E 705
           E
Sbjct: 174 E 174


>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
           Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
          Length = 483

 Score =  131 bits (316), Expect = 2e-29
 Identities = 71/176 (40%), Positives = 108/176 (61%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ TIGPAS +V V+ +M++ GMNVAR+NFSHGS+E HA  +R  R  E+    ++ +P 
Sbjct: 20  IVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQ----EMDTPI 75

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
           +L    D +GP+IR G L GG   E +L++GE + L   P      +   + +DY ++  
Sbjct: 76  TL--LQDLQGPKIRIGQLPGG---EKQLREGEKVSLV--PVEIGDRHPGAVGIDYPHLAT 128

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
             K G RI +DDGL+ +   S+    + C +  GG+L SRKGVNLPG+ + LP+++
Sbjct: 129 EAKVGERILLDDGLLEMKVVSIQDPEVICEVVTGGILKSRKGVNLPGLVLTLPSMT 184


>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
           Pyruvate kinase - Methanosarcina acetivorans
          Length = 489

 Score =  130 bits (315), Expect = 2e-29
 Identities = 72/177 (40%), Positives = 101/177 (57%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CTIGPAS +  VL K++  GMNVAR+NFSHG  E H + IR  R+  +          
Sbjct: 22  IVCTIGPASFSEEVLRKLVLAGMNVARINFSHGDFESHGKVIRRVRKVAEELDR------ 75

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
           ++AI  D  GP+IR G L+      + L KG  I LTT    +  G+ D I V+YK +  
Sbjct: 76  TVAILADLPGPKIRVGKLK---KEPLMLHKGNRITLTTD---ETSGSEDRIPVNYKQLPE 129

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            V PG+ I++ DG I ++C  +S   + C +  GG L S KG+NLPG  + L +V+E
Sbjct: 130 SVSPGSLIYLSDGFIQLLCLEISGKDVVCEVMVGGQLYSHKGLNLPGAKIYLDSVTE 186


>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
           (class)|Rep: Pyruvate kinase - Corynebacterium
           glutamicum (Brevibacterium flavum)
          Length = 475

 Score =  130 bits (314), Expect = 3e-29
 Identities = 65/181 (35%), Positives = 104/181 (57%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CT+GPA  +   + +++E GM+VAR+NFSHG H  H +  +  REA +     +
Sbjct: 3   RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAV 62

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G      I  D +GP+IR G    G +     + GETI++T       +G  D +   YK
Sbjct: 63  G------ILADLQGPKIRLGRFTDGATV---WENGETIRITVD---DVEGTHDRVSTTYK 110

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           N+    KPG+R+ +DDG + ++C SV  + + C +  GG + + KGV+LPG+ + +PA+S
Sbjct: 111 NLAKDAKPGDRLLVDDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVSLPGMDISVPALS 170

Query: 703 E 705
           E
Sbjct: 171 E 171


>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
           Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
           PR1
          Length = 476

 Score =  129 bits (312), Expect = 6e-29
 Identities = 69/177 (38%), Positives = 97/177 (54%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ TIGPAS N   +  +   G NV R+NFSHGSH+ H E I   R+  K  +  LG   
Sbjct: 11  ILATIGPASNNYETISSLAAAGANVFRLNFSHGSHDIHQEVIEIIRKINKEQNLNLG--- 67

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
              I  D +GP+IR G +E  G   VE+K GE I +T  P     G +  +   Y+N+  
Sbjct: 68  ---ILQDLQGPKIRVGEVENNG---VEIKPGEKITITNDPVV---GTSTLVSTVYQNLPQ 118

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            V  G+RI IDDG + ++        + CT+ +GG+L SRKG+NLP   V  P+++E
Sbjct: 119 DVVSGDRILIDDGNLEVVVNDTDGKNVNCTVIHGGILKSRKGINLPNTKVSAPSLTE 175


>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
           Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
           mazei (Methanosarcina frisia)
          Length = 477

 Score =  129 bits (311), Expect = 8e-29
 Identities = 74/177 (41%), Positives = 102/177 (57%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CTIGPAS +  ++ K+M  GMNVAR+NFSHG  E H+  +R  R+     + +LG   
Sbjct: 10  IVCTIGPASSSEEMIRKLMLAGMNVARINFSHGDFESHSRVVRIIRKV----ADELGR-- 63

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
           ++AI  D  GP+IR G LE      V L KG  I LT        GN + I V YK +  
Sbjct: 64  TIAILADLPGPKIRIGKLE---KEPVMLHKGNPITLTID---DTPGNEERIPVSYKQLPE 117

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            V PG+ I++ DG I ++C+ V+   + C +  GG L S KG+NLPG  + L AV+E
Sbjct: 118 SVTPGSLIYLSDGFIQLLCKEVTGKDVLCEVLIGGELYSHKGLNLPGAKIFLDAVTE 174


>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
           aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 515

 Score =  128 bits (309), Expect = 1e-28
 Identities = 74/182 (40%), Positives = 108/182 (59%), Gaps = 1/182 (0%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+CT+GPAS++  +LE ++E GM+VAR+NFSHGSHE HAE I   R A    S K
Sbjct: 10  MRRAKIVCTLGPASQSQDMLEALIEAGMDVARLNFSHGSHEQHAENIAKLRAA----SLK 65

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           L    ++ I  D +GP+IRTG    G +    LK+G    +TT  D   KGN D +   Y
Sbjct: 66  LRK--AVGILGDLQGPKIRTGRFITGSTV---LKEGAIFSITT--DESVKGNDDIVSTTY 118

Query: 520 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696
            ++   V PG+RI +DDGL+ + + ++     L   +  GG L + KG+NLPG+ V   A
Sbjct: 119 AHLAADVNPGDRILLDDGLLELKVLETDKKQLLRTQVVIGGTLKNNKGINLPGVAVRADA 178

Query: 697 VS 702
           ++
Sbjct: 179 LT 180


>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
           group|Rep: Pyruvate kinase - Bacillus anthracis
          Length = 352

 Score =  127 bits (307), Expect = 2e-28
 Identities = 68/176 (38%), Positives = 102/176 (57%)
 Frame = +1

Query: 178 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 357
           +CTIGPAS N   L K++  GM + R+N SHG+HE H + IR  +  + S          
Sbjct: 6   VCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDS---------- 55

Query: 358 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNV 537
           + I  D +GP+IR G ++G    ++ L+ G++  L T P     G++    VDY+ I N 
Sbjct: 56  IKILGDVQGPKIRLGEIKG---EQITLQAGDSFMLRTQP---VTGSSTEASVDYEGIAND 109

Query: 538 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           VK G+RI ++DG + +I + VS D +   ++ GG + S KGVNLPG  V LPA++E
Sbjct: 110 VKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVSLPAITE 165


>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
           Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
          Length = 491

 Score =  126 bits (304), Expect = 5e-28
 Identities = 69/182 (37%), Positives = 106/182 (58%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GPAS +  VL++M+  G++VAR+NFSHG HE HA+ +   R A    S  
Sbjct: 4   MRRAKIVATLGPASSDPDVLQRMLAAGVDVARLNFSHGRHEDHAQMLDRIRTA----SRH 59

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           LG   ++A+  D +GP+IRTG L  G    V L+ G  + + T  D + KG+A  +   Y
Sbjct: 60  LGR--AVAVLQDLQGPKIRTGPLAAGREG-VRLEAGAELVIAT--DAEVKGDAKLVSTTY 114

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
            ++   V+PG+R+ +DDGLI +           C +  GG+L   KG+NLPG+ +   A+
Sbjct: 115 PHLAEDVRPGDRLLVDDGLIELRVLETDGVRARCQVVEGGVLREHKGINLPGVALRAEAL 174

Query: 700 SE 705
           SE
Sbjct: 175 SE 176


>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
           bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
           bacteriovorus
          Length = 495

 Score =  123 bits (296), Expect = 5e-27
 Identities = 69/177 (38%), Positives = 102/177 (57%), Gaps = 2/177 (1%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ TIGPA+R+   LEK ++ GMNVAR+NFSHGSHE H + + + R+  K   A  
Sbjct: 5   RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQA-- 62

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
                +AI  D +GP+IR G  E G    +E+K GE + +TT+   +  G    +  D++
Sbjct: 63  ----PVAILQDLQGPKIRVGKFENG---SIEIKPGEKLVVTTA---KVLGKPGLVPSDFQ 112

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI--PVD 687
            +     PG RI +DDGL+ +    V  + +   +  GG+L  RKG+NLPG+  PVD
Sbjct: 113 ELPLACVPGTRILLDDGLMEVKVLQVRGEEIDVEVVYGGILKDRKGMNLPGVNLPVD 169


>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
           acetoxidans DSM 684|Rep: Pyruvate kinase -
           Desulfuromonas acetoxidans DSM 684
          Length = 474

 Score =  122 bits (295), Expect = 7e-27
 Identities = 69/182 (37%), Positives = 108/182 (59%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+CT+GPAS + A LE+M+ +GMNVAR+NFSHG H+ H + I   R   K    +
Sbjct: 1   MRRTKIVCTVGPASADEATLEQMISSGMNVARLNFSHGDHDSHQQLIERIRAVAK----R 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           L  P  +AI  D  GP+IR G L   G   V L +G+ + L ++    + G  D + VDY
Sbjct: 57  LNQP--VAILQDLCGPKIRLGQLPEQG---VRLHQGDAVSLCST---GQAGEGD-LPVDY 107

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
            ++   V+ G+ I + DGL+ +  + + A  + C++ +GG+  SRKGVN+P   + +PA 
Sbjct: 108 PSLHEDVQVGDSIMLSDGLMELQVERIDAPQVQCSVISGGVAYSRKGVNMPSSHLSIPAF 167

Query: 700 SE 705
           +E
Sbjct: 168 TE 169


>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
           Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 481

 Score =  122 bits (294), Expect = 9e-27
 Identities = 69/182 (37%), Positives = 105/182 (57%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + IICT+GPAS    V+E ++  GMNVAR+NFSHG +E H   +   R+     S K
Sbjct: 16  MRKAKIICTLGPASDTPEVIEGLVRAGMNVARINFSHGVYEDHRRRVNTLRKV----SRK 71

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           LG P  +AI  D +GP+IR G  EGG   ++ ++ G+T+ +TT       G    I    
Sbjct: 72  LGIP--VAILQDIQGPKIRLGRFEGG---QLLVQAGQTVTVTTR---AVLGQGTLIPTPV 123

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
           +++T  V  G+ I +DDG + +    V+   +T T+E GG+L   KG+NLPG  + +P +
Sbjct: 124 RSLTRDVTRGDMILLDDGRVRLRVVRVAGRDVTATVEVGGLLKDHKGLNLPGAAISVPTI 183

Query: 700 SE 705
           +E
Sbjct: 184 TE 185


>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
           DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
           (strain DSM 13855)
          Length = 476

 Score =  121 bits (291), Expect = 2e-26
 Identities = 62/181 (34%), Positives = 102/181 (56%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CT+GPA+ +   L +++  GM+VARMNFSHG+HE H E +   RE  ++     
Sbjct: 3   RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEAEGK-- 60

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
                + +  D +GP+IR G ++   +  V L +G+ ++++T  D   +   + I++DY+
Sbjct: 61  ----GITVLQDLQGPKIRVGAVQ---NDSVMLAEGDEVRVST--DTPRESTNEHIFIDYE 111

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +    + G RI IDDGL+ +     +   L  T+  GG L SRKGVNLP +    P ++
Sbjct: 112 ALARDAREGERILIDDGLLELRVIETNGSQLRATVVEGGPLRSRKGVNLPDLQASTPPMT 171

Query: 703 E 705
           E
Sbjct: 172 E 172


>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
           dehalogenans 2CP-C|Rep: Pyruvate kinase -
           Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 489

 Score =  120 bits (289), Expect = 3e-26
 Identities = 66/182 (36%), Positives = 106/182 (58%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GPAS    VL +++E G++VAR+NFSHG HE HA  +   R A    S  
Sbjct: 1   MRRAKIVATLGPASGEPDVLARLLEQGVDVARLNFSHGRHEDHARMLDKIRAA----SRH 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           LG   ++A+  D +GP+IRTG L+  G A V+++ G+ + +TT  +    G+A  +   Y
Sbjct: 57  LGK--AVAVLQDLQGPKIRTGPLK-AGKAGVQVEAGQELVITTEGEL--PGDAHLVSTTY 111

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
            ++   V+ G+R+ +DDGL+     +     +   +  GG LG  KG+NLPG+ +   A+
Sbjct: 112 PHLAEDVRAGDRLLVDDGLLEFRVLATDGVRVRTEVVEGGWLGEHKGINLPGVALRAEAL 171

Query: 700 SE 705
           SE
Sbjct: 172 SE 173


>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
           ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 492

 Score =  120 bits (288), Expect = 5e-26
 Identities = 70/181 (38%), Positives = 105/181 (58%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R   I+CTIGPASR+ A+L KM+ +GMNVAR+NFSHG+HE H       REA    + +L
Sbjct: 24  RACRIVCTIGPASRSPAILRKMLLSGMNVARLNFSHGNHESHGRIACEIREA----AQRL 79

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
             P  +AI  D +G ++R G ++   S  + L++G+ I L     + E  ++  I +DY+
Sbjct: 80  MKP--VAILQDLQGHKVRVGKVQHPPS--LSLEEGQEILL----GHGETISSKRIGIDYQ 131

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           +I   V PG ++F+DD  I +   S+    L C ++ GG L SRKGV  P   +  P ++
Sbjct: 132 DIIQYVTPGQKVFLDDASIELEVLSIEEKDLHCQVKFGGQLRSRKGVIFPDSQLSFPLLN 191

Query: 703 E 705
           E
Sbjct: 192 E 192


>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
           Pyruvate kinase - Propionibacterium acnes
          Length = 477

 Score =  118 bits (285), Expect = 1e-25
 Identities = 65/185 (35%), Positives = 106/185 (57%), Gaps = 3/185 (1%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GPA  +   ++++ME GMN+AR+N SHG +  H E +    +  +S S +
Sbjct: 1   MRRAKIVNTLGPAVTSHDAMKELMEAGMNIARLNMSHGDYSEHQERL----DLVRSVSKE 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLE---GGGSAEVELKKGETIKLTTSPDYQEKGNADTIY 510
           LG   ++A   D +GP+IRTGL E   G  + +++LK G+   +TT       GN + + 
Sbjct: 57  LG--LNVAALADLQGPKIRTGLFEKAEGESNGKIDLKIGDKFTITTDDIV---GNQERVS 111

Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690
             +K +    KPG+ I IDDG   +   SVS + + C     G +G  KG+NLPG+ V +
Sbjct: 112 TTFKGLPQDCKPGDVILIDDGKTVLQVDSVSGNDVNCHCTVAGPVGDHKGINLPGVAVSI 171

Query: 691 PAVSE 705
           PA+++
Sbjct: 172 PALTK 176


>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
           Pyruvate kinase - Mycobacterium tuberculosis
          Length = 472

 Score =  118 bits (285), Expect = 1e-25
 Identities = 60/181 (33%), Positives = 99/181 (54%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R   I+CT+GPA++   ++  ++E GM+VARMNFSHG ++ H       R A  +    +
Sbjct: 3   RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAV 62

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G      +  D +GP+IR G    G +   E   GET+++T       +G+ D +   YK
Sbjct: 63  G------VLADLQGPKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYK 110

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +      G+R+ +DDG ++++  +V  D + CT+  GG +   KG++LPG+ V  PA+S
Sbjct: 111 RLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALS 170

Query: 703 E 705
           E
Sbjct: 171 E 171


>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
           Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 610

 Score =  118 bits (284), Expect = 1e-25
 Identities = 65/182 (35%), Positives = 102/182 (56%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+CT+GPAS +V  +  + + GM+VAR+N SHGS E+  E I   R+ +++    
Sbjct: 15  MRSAKIVCTLGPASDSVDDIASLAKAGMSVARLNASHGSPEHRREMIDRIRQVDEAVEEP 74

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           +      A  LD  GPE+RT  ++      ++L +G TI+     D      A    V  
Sbjct: 75  V------AAMLDMPGPEVRTAEID----EPIQLTEGSTIRYVVGDD------ATPEEVGL 118

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
                 V+PG+R+ +DDG I    + V  +T+  T+ENGG L +RKGVN+PG+ +DLP +
Sbjct: 119 SQSITAVEPGDRVLLDDGRIETTVERVEDETVFATVENGGELAARKGVNVPGVELDLPTI 178

Query: 700 SE 705
           +E
Sbjct: 179 TE 180


>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
           bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
           bacterium TAV2
          Length = 480

 Score =  118 bits (283), Expect = 2e-25
 Identities = 65/184 (35%), Positives = 109/184 (59%), Gaps = 2/184 (1%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           IR + I+ T+GPA+ +  +LEK++  G +VAR+N +H +HE+    IR  RE  K    +
Sbjct: 10  IRRTKIVFTLGPATESEEMLEKLIRAGADVARLNMAHANHEWTRMIIRRIREVSK----R 65

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNAD--TIYV 513
           +G    +AI +D KGPEIRTG +    S+ +ELK GE    T  P   +  + +  ++ V
Sbjct: 66  VGR--EIAIMMDIKGPEIRTGDV----SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDV 119

Query: 514 DYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLP 693
           +YK++ N ++ G+ + +D+GLI +         + C +   G L SR+ +NLPG+ V+LP
Sbjct: 120 NYKDLVNDIRVGDTVLVDNGLIRLEVLEKQNTRIRCRVLIPGELKSRRHINLPGVKVNLP 179

Query: 694 AVSE 705
           +++E
Sbjct: 180 SLTE 183


>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
           organisms|Rep: Pyruvate kinase - Uncultured methanogenic
           archaeon RC-I
          Length = 583

 Score =  117 bits (282), Expect = 2e-25
 Identities = 66/182 (36%), Positives = 100/182 (54%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+CTIGPA  +  +LEK+   GMNVAR+N SH  HE+  +TI N R      S  
Sbjct: 1   MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIR----MVSEA 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           +G P  + I +D +GP+IR G L+        LK G T  LTT       G++  + V +
Sbjct: 57  IGKP--IGILMDLQGPKIRVGTLQ----QPANLKPGGTFTLTTR---DVPGDSQEVNVPF 107

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
           K +   V  G  + +DDGLI +   +V+   +   +  GG L S+KG+NLP   + +P++
Sbjct: 108 KELPQSVSTGQTLLLDDGLIELKVDAVTETDIRTKVVRGGELKSKKGINLPQSTIRIPSI 167

Query: 700 SE 705
           +E
Sbjct: 168 TE 169


>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
           Pyruvate kinase - Vitis vinifera (Grape)
          Length = 621

 Score =  116 bits (279), Expect = 6e-25
 Identities = 63/181 (34%), Positives = 107/181 (59%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CTIGP++ +  ++ K+ ETGMNVAR+N SHG H  H +TI   +E    +  K+
Sbjct: 166 RKTKIVCTIGPSTSSREMIWKLAETGMNVARLNMSHGDHASHKKTIDLVKEYNAQFEDKV 225

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
                +AI LDTKGPE+R+G +       + LK+G+    T     +   + +T+ V+Y 
Sbjct: 226 -----IAIMLDTKGPEVRSGDV----PKPIMLKEGQEFNFTIK---RGVSSENTVSVNYD 273

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           +  N V+ G+ + +D G++S+  +S S D + C + +GG L SR+ +N+ G    LP+++
Sbjct: 274 DFVNDVEVGDILLVDGGMMSLAVKSKSKDLVKCQVIDGGELKSRRHLNVRGKSATLPSIT 333

Query: 703 E 705
           +
Sbjct: 334 D 334


>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
           Pyruvate kinase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 485

 Score =  115 bits (277), Expect = 1e-24
 Identities = 63/177 (35%), Positives = 104/177 (58%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ TIGPAS +  +LE+++ TG++VAR+NFSHG    H E I N R A    S + G   
Sbjct: 10  IVGTIGPASESPEMLERLIRTGLDVARLNFSHGDFSGHRERIANLRAA----SDRAGR-- 63

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
           ++A+  D  GP++R G ++   +  + L+ G+   LTT       G+     + +  +  
Sbjct: 64  AVAVLADLPGPKMRLGTIQ---NEPIHLRAGDPFTLTTDSIV---GDNRRCSMSFAALPQ 117

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           VVKPG+R++++DGL+ ++ + +    + C +  GG L SRKG+NLPGI + + A +E
Sbjct: 118 VVKPGDRLYLNDGLVHLLVERIEGTDVHCVVAVGGELRSRKGLNLPGINLGISAFTE 174


>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
           Pyruvate kinase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 509

 Score =  115 bits (276), Expect = 1e-24
 Identities = 62/180 (34%), Positives = 99/180 (55%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CTIGPA    A ++++M  GM+VAR+NFSHG+H+ H   I+  R+         
Sbjct: 20  RRAKIVCTIGPACNTEAAMQELMRAGMDVARLNFSHGTHDEHLVVIQRLRKVAAEEQR-- 77

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
               S+ I  D +GP+IRTGLL+      V L+ G T+ +T        G+A  +   ++
Sbjct: 78  ----SICILQDLQGPKIRTGLLK--DHKPVMLETGNTVTITPR---DIVGDASLLATTFQ 128

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +   V+PG+RI + DG I +    +    + C I NGG L   +G+N+PG  + +PA++
Sbjct: 129 TLALDVQPGSRILLSDGKIELSVSRIEGADVECHIVNGGELKEHQGINIPGAILSIPALT 188


>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
           Pyruvate kinase - Thermococcus litoralis
          Length = 220

 Score =  115 bits (276), Expect = 1e-24
 Identities = 63/176 (35%), Positives = 105/176 (59%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II TIGPAS+    ++KM++ GM+VAR+NFSHG+ E HA+TI   R+  +    +     
Sbjct: 14  IIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERR----- 68

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            +AI  D  G ++R G ++G     V L+KG+ + LTT      +G+  TI V++K++  
Sbjct: 69  -VAILGDLPGLKMRVGKIKGD---SVTLRKGDKVVLTTR---DIEGDETTIPVEFKDLPK 121

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           +V  G+ I++ DG I +  + V  + + C + NGG+L S KG+N+P   + + A++
Sbjct: 122 LVSKGDTIYLSDGYIMLRVEEVRENEVECVVVNGGILFSHKGINIPKANLPIEAIT 177


>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
           proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
           uncultured delta proteobacterium DeepAnt-32C6
          Length = 466

 Score =  114 bits (275), Expect = 2e-24
 Identities = 65/182 (35%), Positives = 98/182 (53%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+CTIGPA+     +  +++ GM+ AR+NFSHG+ + HA      RE     + +
Sbjct: 1   MRRAKIVCTIGPATHTREGIRALIDAGMDCARLNFSHGTQQGHARVAALVREL----ATE 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
            G P  +A+  D  GP+IR G    G    VEL +G    LTT       G      ++Y
Sbjct: 57  AGRP--IALLADLCGPKIRVGRFPEGA---VELVEGTAFTLTTR---DVAGTDKQASINY 108

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
             +   V PG+ I IDDGLI ++ + V    + C +E GGML  RKG+N+PG  +  PA+
Sbjct: 109 AALPQDVDPGDAIMIDDGLIRLVVREVEGPDIHCIVEVGGMLSERKGINVPGSALSTPAL 168

Query: 700 SE 705
           ++
Sbjct: 169 TD 170


>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
           proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
           proteobacterium MLMS-1
          Length = 493

 Score =  114 bits (275), Expect = 2e-24
 Identities = 66/181 (36%), Positives = 102/181 (56%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CTIGPA+ +   + ++ E GMNVAR+N SHGS E+H   I N +   K Y+   
Sbjct: 16  RRTKIVCTIGPATASFEAICRLAEQGMNVARLNMSHGSREWHRGVIGNIKRYNKKYAG-- 73

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
               SLA+ LDT+G EIR+G L+     ++EL+ G+ + LTT    Q +     + V + 
Sbjct: 74  ----SLAVLLDTRGAEIRSGDLK----QDLELRVGDGLTLTTR--RQAELEPGCVEVSHD 123

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
                V PG+ I +D G++ +    V    + C   + G+LGSR+ +N+ G   DLPA++
Sbjct: 124 GFVAEVTPGDIILVDGGMLRLKVVEVGRTDVRCQSLDEGVLGSRRHLNIRGKSADLPAIT 183

Query: 703 E 705
           E
Sbjct: 184 E 184


>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
           Pyruvate kinase - Monocercomonoides sp. PA203
          Length = 516

 Score =  114 bits (275), Expect = 2e-24
 Identities = 63/186 (33%), Positives = 105/186 (56%), Gaps = 1/186 (0%)
 Frame = +1

Query: 151 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 330
           +S+  L+ I+ T+GPA+     + +++  G+NV RMNFSHG+HE+H +  +  R+  +  
Sbjct: 32  ASFTPLTKIVATLGPATSTYETISQVVTAGVNVIRMNFSHGTHEFHEQLYKIVRKVAED- 90

Query: 331 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY 510
              LG    +AI  D +GP++RT    GG   ++ +K+G+ + +  SP+  + G   T +
Sbjct: 91  ---LGK--EVAIIADLQGPKVRTNTFPGG---KITIKRGDKVSIVGSPEPGKPGVITTKF 142

Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV-D 687
                  NV +P   + IDDGLI +I Q  + + L C +E GG +   KG+NLP   +  
Sbjct: 143 TPMITHCNVGEP---VLIDDGLIRLIVQEKNPNELVCLVEQGGDVKDHKGINLPATDLGP 199

Query: 688 LPAVSE 705
           LPA++E
Sbjct: 200 LPALTE 205


>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
           kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
           B - Apis mellifera
          Length = 538

 Score =  113 bits (273), Expect = 3e-24
 Identities = 60/210 (28%), Positives = 110/210 (52%), Gaps = 2/210 (0%)
 Frame = +1

Query: 82  EKPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMN 261
           E+   A   ++L+H   L+I+S     RL+ I+ T+G  + +   +  +M  G N+ R+N
Sbjct: 12  EQIKAAYQNTRLEHNINLNINSSPKLARLTRIMVTLGRRNSHPEAVVSIMMAGANIVRLN 71

Query: 262 FSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSA--EVE 435
            +H + ++H  T+++ R+A  +        + L +A++ +GPEIR G   G  ++    +
Sbjct: 72  MAHETDKWHTATVQSVRKAGNTMYEFTSEIYPLGVAINLQGPEIRAGAFRGDKTSLGYAK 131

Query: 436 LKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTL 615
           LK+G+ +KL T    +  G A+  +V Y N+  + + G+RI ID G + +    +    +
Sbjct: 132 LKEGKMVKLVTQDIAKRAGRANCFWVSYPNLPKICQVGDRILIDRGAVLLQVTCIHEQAI 191

Query: 616 TCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           TC I  GG++   K + L    V LP +SE
Sbjct: 192 TCKIIKGGIVKDGKLIQLLDSLVPLPQISE 221


>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
           Pyruvate kinase - Leptospira interrogans
          Length = 478

 Score =  113 bits (272), Expect = 4e-24
 Identities = 63/177 (35%), Positives = 99/177 (55%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CTIGPAS +   +  +++ GM++ARMNFSHG+H+ H       R+ E+ +       F
Sbjct: 14  IVCTIGPASSSEETILSILKAGMDIARMNFSHGTHDSHKRVYDTLRKCEQIFG------F 67

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            L I  D +GP+IRTG L+      + L K + I++   PD    G+   I   Y N+  
Sbjct: 68  PLGIMADLQGPKIRTGKLK---LNSILLHKNQEIEIV--PDSDILGDEHKIGCTYPNLIR 122

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            ++  ++I IDDG + +   S  +++    +  GG+L S KG+NLPG P+  PA+SE
Sbjct: 123 DIQEEDKILIDDGKLILKVISKKSNSAILKVIVGGILWSNKGINLPGTPISAPALSE 179


>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
           precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
           isozyme G, chloroplast precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 562

 Score =  113 bits (272), Expect = 4e-24
 Identities = 64/195 (32%), Positives = 109/195 (55%), Gaps = 3/195 (1%)
 Frame = +1

Query: 130 GLDIDSKSSYI---RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETI 300
           G  +  +S Y+   R + I+CTIGP++ +  ++ K+ E GMNVAR+N SHG H  H  TI
Sbjct: 77  GYSLGQESVYLNSPRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTI 136

Query: 301 RNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDY 480
              +E    +  K+     +AI LDTKGPE+    + G     + LK+G+    +     
Sbjct: 137 DLVKEYNAQFEDKV-----IAIMLDTKGPEV----ISGDVPKPILLKEGQEFNFSIK--- 184

Query: 481 QEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKG 660
           +     DT+ V+Y +  N V+ G+ + +D G++S+  +S ++D + C + +GG L SR+ 
Sbjct: 185 RGVSTEDTVSVNYDDFINDVEAGDILLVDGGMMSLAVKSKTSDIVKCEVIDGGELKSRRH 244

Query: 661 VNLPGIPVDLPAVSE 705
           +N+ G    LP+++E
Sbjct: 245 LNVRGKSATLPSITE 259


>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
           unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
          Length = 477

 Score =  113 bits (271), Expect = 5e-24
 Identities = 62/177 (35%), Positives = 100/177 (56%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CTIGPAS+ V  L KM+E GMN+AR+NF+HGS E H   + N R+A K          
Sbjct: 11  IVCTIGPASQEVETLTKMIENGMNIARINFAHGSFEEHETVVENIRKASKIVGK------ 64

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            + I  D  GP+IR G ++      +E+KKG+ + L+      EK     I +++K+ + 
Sbjct: 65  DVTIMGDLPGPKIRIGDIK-----PMEIKKGDILILS------EKPQEGVIPINFKDFSK 113

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            VK G+ I+++DG + ++ + V  D +     + G + S KGVNLP + + + A+ +
Sbjct: 114 YVKVGDSIYMNDGFVELMVEKVEDDKVYAVSLSAGKISSHKGVNLPNVDLPVRAIGD 170


>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
           SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
          Length = 478

 Score =  112 bits (270), Expect = 7e-24
 Identities = 61/177 (34%), Positives = 104/177 (58%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CTIGPA+++  +++K++  GMNVAR+N SH +   H + +   ++  K     L  PF
Sbjct: 12  IVCTIGPATQDETMIKKLINAGMNVARLNTSHDTIADHEKRVNLIKKIRKD----LNIPF 67

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
             AI LD +GP+IRTG  E   + +V L++G+   LT     +  GN + + ++Y+ +  
Sbjct: 68  --AILLDLEGPKIRTGKFE---TDQVMLEEGQKFILTIE---EIVGNKERVSINYRELPK 119

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            VK G+ I +DDG I ++  S +   +   +  GG +  R+G+N+PGI + LP ++E
Sbjct: 120 EVKKGDFILLDDGKIRLVVVSSNEKEIVTKVVTGGSITHRRGINVPGIDISLPPLTE 176


>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Deinococcus radiodurans
          Length = 482

 Score =  112 bits (269), Expect = 9e-24
 Identities = 63/181 (34%), Positives = 99/181 (54%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ T+GPASR+  VL +M++ G+NV R+NFSHG  E H +T++  R+   S    +
Sbjct: 6   RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVSKGVTI 65

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G      I  D +GP+IR G    G    V L  G+   +T     + +GNA+ +   YK
Sbjct: 66  G------ILQDLQGPKIRVGRFAEG---SVTLNPGQKFVITMD---EVEGNAERVGSTYK 113

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +   V PG  + +DDG +S+    V  + +  T+  GG L + KG+N+P   + +PA+S
Sbjct: 114 GLAGDVTPGMTLLLDDGNMSLRVDHVRGNDIQTTVLIGGTLKNNKGINVPEADLTVPALS 173

Query: 703 E 705
           E
Sbjct: 174 E 174


>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
           Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
           Protochlamydia amoebophila (strain UWE25)
          Length = 598

 Score =  111 bits (268), Expect = 1e-23
 Identities = 68/177 (38%), Positives = 99/177 (55%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CTIGPA  ++  + +++  GMNVAR+NFSHG+ E H  TI   +EA      +L  P 
Sbjct: 8   IVCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEAR----CQLNLP- 62

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            LAI LDTKGPEIR G +  G   ++ L  G+  +L      +  G+   + +   NI +
Sbjct: 63  -LAIMLDTKGPEIRLGKIRDG---QIFLTVGQKWRLVKK---EVLGDESQVSIFPLNILD 115

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            +  G  I  DDG I+      S++ +   I N GM+ S KGVN+P   ++LPAV+E
Sbjct: 116 QLPVGTTILFDDGYIASRVIENSSEGVLVEINNSGMIRSSKGVNIPNTSLNLPAVTE 172


>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 579

 Score =  111 bits (267), Expect = 2e-23
 Identities = 63/187 (33%), Positives = 105/187 (56%)
 Frame = +1

Query: 145 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 324
           SK +  R + I+CT+GP++    ++ K+ E GMNVARMN SHG H  H + I    +  K
Sbjct: 104 SKPTVRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVI----DLVK 159

Query: 325 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADT 504
            Y+A+     ++AI LDTKGPE+R+G L       + L  G+    T     +       
Sbjct: 160 EYNAQT-KDNTIAIMLDTKGPEVRSGDL----PQPIMLDPGQEFTFTIE---RGVSTPSC 211

Query: 505 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 684
           + V+Y +  N V+ G+ + +D G++S + +S + D++ C + +GG L SR+ +N+ G   
Sbjct: 212 VSVNYDDFVNDVEAGDMLLVDGGMMSFMVKSKTKDSVKCEVVDGGELKSRRHLNVRGKSA 271

Query: 685 DLPAVSE 705
            LP+++E
Sbjct: 272 TLPSITE 278


>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 477

 Score =  111 bits (266), Expect = 2e-23
 Identities = 62/183 (33%), Positives = 105/183 (57%), Gaps = 1/183 (0%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GPA+ +   +  ++  G++V R+NFSHG+H+ H +  R  REA    +A+
Sbjct: 3   VRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREA----AAE 58

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
            G   ++AI  D +GP+IRTG +EGG     EL +G  + +    D+   G+A  +   Y
Sbjct: 59  AGR--NVAIMQDLQGPKIRTGEVEGG----TELVEGSRVVIAPG-DF--VGDASRLSTSY 109

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSAD-TLTCTIENGGMLGSRKGVNLPGIPVDLPA 696
             +   VKPG+R+ IDDGLI +  +S+  +  + C +  GG + S KG+N P   + +  
Sbjct: 110 DRLAQDVKPGHRLLIDDGLIGLRVESIKENGEIVCEVLEGGPVSSHKGLNFPDSSLSISG 169

Query: 697 VSE 705
           ++E
Sbjct: 170 LTE 172


>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG7070-PB, isoform B - Tribolium castaneum
          Length = 535

 Score =  110 bits (265), Expect = 3e-23
 Identities = 61/193 (31%), Positives = 101/193 (52%)
 Frame = +1

Query: 115 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 294
           L+H+  L   S+    RL+     I P   ++  +E+ ++ GM VA +   + + +   E
Sbjct: 44  LEHLARLQEKSRVRRKRLTQFSVIIPPRI-SIEHIEEFLKAGMTVALIRMDYFTVDEIEE 102

Query: 295 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSP 474
            +   R     +  K+G  + +AI LD    EI+TG L      E+EL+KG+T K+   P
Sbjct: 103 MVAMIRNVVDDFGKKIGRVYPIAIGLDVSEQEIKTGKLLKP-LKEIELEKGQTTKIVAKP 161

Query: 475 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 654
           ++  + + + IYV+Y+NI +VVKPG+ + I D  I +    V+ D + C IE  G+L   
Sbjct: 162 EFANRVSKEFIYVNYENIADVVKPGDSLIIGDDNIRMSAIEVARDIINCIIEKAGLLTDN 221

Query: 655 KGVNLPGIPVDLP 693
             V LP +P+ LP
Sbjct: 222 LSVKLPNVPITLP 234


>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
           Pyruvate kinase - Anabaena sp. (strain PCC 7120)
          Length = 476

 Score =  109 bits (263), Expect = 5e-23
 Identities = 66/183 (36%), Positives = 106/183 (57%), Gaps = 1/183 (0%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + IICT+GPA+     LE ++E GMNVAR+NFSHG++++HA+T +  R+     SA 
Sbjct: 1   MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQ----ISAD 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNA-DTIYVD 516
              P  +AI  D  GP+IR G L   G   + ++ G+ +        QEKG++ D + + 
Sbjct: 57  RQKP--VAIMQDLCGPKIRLGTLPPEG---LMVEAGQEVTFV----LQEKGSSLDELPLP 107

Query: 517 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696
              +  +V+PG  I I+DG + +I     AD +    + GG+L +RKGVNLP   + + +
Sbjct: 108 LPTLFAMVRPGEPILINDGRVKLIVTDRDADRIRAIAKIGGLLSTRKGVNLPATRLPVSS 167

Query: 697 VSE 705
           ++E
Sbjct: 168 ITE 170


>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
           Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
          Length = 482

 Score =  109 bits (263), Expect = 5e-23
 Identities = 64/176 (36%), Positives = 95/176 (53%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R S I+ T+GPAS +  +L  +   G++  R+NFSHG+   HAE  RN R  E+ + A  
Sbjct: 7   RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDA-- 64

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
               ++A+  D +GP+IR G+L  G    ++L +G TI      +  E  N   I + ++
Sbjct: 65  ----AIAVLQDLQGPKIRIGVLAHG---RLDLARGSTIGFILGREGGEGMN--DIPLPHR 115

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690
            I  V  PG  + IDDG I +    V    L C + NGG L +RKGVN+PG  +D+
Sbjct: 116 EIFEVAVPGMDLLIDDGRIKVRIMEVMDGRLVCEVLNGGALSNRKGVNVPGAVLDI 171


>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to pyruvate kinase - Candidatus Kuenenia
           stuttgartiensis
          Length = 472

 Score =  109 bits (261), Expect = 9e-23
 Identities = 66/181 (36%), Positives = 100/181 (55%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CTIGPAS + A++E+++  GMNVAR+NFSHG    H E I + R    + S KL
Sbjct: 5   RKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIR----AISEKL 60

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
             P  +A+  D  GP+IR G+L G     V LK  +T  LTT       GN   I ++Y 
Sbjct: 61  MQP--VAVLQDLSGPKIRIGMLSGDA---VTLKTNDTFTLTTR---NIVGNERVISINYS 112

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           ++   V  G+ + + DG I +         + C +  GG+L SRKG+N+P   + + +++
Sbjct: 113 DLPMNVSIGDTLLLSDGEIEVEVIQKDDRNIHCKVIVGGVLTSRKGINIPARSLPVSSLT 172

Query: 703 E 705
           E
Sbjct: 173 E 173


>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
           Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 613

 Score =  108 bits (259), Expect = 2e-22
 Identities = 68/207 (32%), Positives = 107/207 (51%), Gaps = 3/207 (1%)
 Frame = +1

Query: 91  TVANVGSQLQHMCGLDID-SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFS 267
           TV NV S     CG  +  +KS  +R + I+CTIGPAS +   +  + + GM+V R+N S
Sbjct: 5   TVTNVHSVATQPCGFFLSCAKSGDMRNAKIVCTIGPASDSRDAIRDLADAGMSVVRLNAS 64

Query: 268 HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKG 447
           HG+  +  E I   R  +     ++  P  LA+ +D KGPE+RT  L+            
Sbjct: 65  HGTTAHREEVIERARAVDN----EIDDP--LAVMVDLKGPEVRTAELD------------ 106

Query: 448 ETIKLTTSPD--YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTC 621
           E+I L T  +  + E  +A    V   +      PG+ + +DDG I    + V  +++  
Sbjct: 107 ESISLATGSEVTFVEGDDATPERVGLTHSIAAAGPGDTVLLDDGRIECRVERVDGESVVA 166

Query: 622 TIENGGMLGSRKGVNLPGIPVDLPAVS 702
           T+ +GG L SRKGVNLPG+ +D+  ++
Sbjct: 167 TVVSGGKLSSRKGVNLPGVAIDVDLIT 193


>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
           Pyruvate kinase - Parabacteroides distasonis (strain
           ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 485

 Score =  107 bits (256), Expect = 3e-22
 Identities = 65/177 (36%), Positives = 96/177 (54%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ T+     +VA +E + + GMNV R+N +H   E     + N R    + S ++G   
Sbjct: 7   IVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVR----TVSDRIG--- 59

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
              I +DTKGPE+RT          +  K GE +K+  +PD QE  + D I V YKN  N
Sbjct: 60  ---ILMDTKGPEVRTTTTVN--KEPIPFKTGEIVKVIGNPD-QETSH-DCICVSYKNFVN 112

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            +  G+ I IDDG + +     S D L C I+N   LGSRK VN+PG+ ++LP+++E
Sbjct: 113 DLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNVPGVRINLPSLTE 169


>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
           smegmatis str. MC2 155|Rep: Pyruvate kinase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 477

 Score =  107 bits (256), Expect = 3e-22
 Identities = 57/181 (31%), Positives = 96/181 (53%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CT+GPA+   +VL ++++ GM+VAR+NFSH +H  H+      RE        +
Sbjct: 4   RRAKIVCTLGPATATSSVLTELVDAGMDVARLNFSHSTHAEHSALYGMVREIAAQRGRVV 63

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G      +  D +GP+IR G    G    V    GE + +TT       G+ D +   Y 
Sbjct: 64  G------VLADLQGPKIRLGCFADG---PVVWATGEHVTITTEDC---PGDHDRVSTTYA 111

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            ++  V+ G+R+ +DDG + +   +V    + C + +GG +   KG++LP IPV +P +S
Sbjct: 112 GLSQDVRAGDRLLVDDGRVDLRVVAVDGPDIRCEVVDGGPVSDHKGISLPNIPVSVPPLS 171

Query: 703 E 705
           +
Sbjct: 172 D 172


>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
           Pyruvate kinase - Chlamydia trachomatis
          Length = 485

 Score =  106 bits (254), Expect = 6e-22
 Identities = 62/177 (35%), Positives = 95/177 (53%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           IICTIGPA+    +LEK+++ GMNVAR+NFSHG+HE H  TI   +E  +          
Sbjct: 7   IICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQV------ 60

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            LAI LDTKGPEIR G +E    + ++++ G+ + L +      K +  T+Y     +  
Sbjct: 61  PLAIMLDTKGPEIRLGQVE----SPIKVQPGDRLTLVSKEILGSKESGVTLYPSC--VFP 114

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            V+    + IDDG I  +  +     +    +N G + S K +++  I V LP ++E
Sbjct: 115 YVRERAPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIKDIDVALPFMTE 171


>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
           Proteobacteria|Rep: Pyruvate kinase family -
           Nitrosomonas europaea
          Length = 496

 Score =  105 bits (252), Expect = 1e-21
 Identities = 59/181 (32%), Positives = 100/181 (55%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GPAS N  VL +M+E G++V R+NFSHG+ + H  ++    E  +S +  
Sbjct: 2   MRRTKIVATLGPASSNAEVLGRMLEAGVDVIRINFSHGTKDEHIASV----ELVRSLARS 57

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           LG   ++ +  D +GP+IR G  E G   ++ LK G+   L       + GN + + +DY
Sbjct: 58  LGR--TVGVLADLQGPKIRIGKFEQG---KIRLKTGDEFILDAE---CQLGNQERVGLDY 109

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
           + + N V+ G  + +DDG I +    V    + C +  GG+L + KG+N  G  +  PA+
Sbjct: 110 RELPNDVEAGATLLLDDGRIVLTVAKVRESEIFCEVLQGGILSNNKGINRKGGGLSAPAL 169

Query: 700 S 702
           +
Sbjct: 170 T 170


>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
           Pyruvate kinase - Synechococcus sp. (strain
           JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
           B-Prime)
          Length = 619

 Score =  105 bits (252), Expect = 1e-21
 Identities = 67/182 (36%), Positives = 95/182 (52%), Gaps = 2/182 (1%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ TIGPAS N A+L +M+  G    R+NFSHG HE H  +IR  R+     +  L
Sbjct: 8   RRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQT----AMDL 63

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G    +AI  D +GP+IR G    G    + LK G+   LT+ P     G+ +  +V Y 
Sbjct: 64  G--IQVAILQDLQGPKIRLGKFAEG---SITLKAGDPFVLTSKP---VLGSQERSWVTYD 115

Query: 523 NITNVVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696
            +   V  G  I IDDG + +  ++V   A  L C    GG L + KGVN PG+ + + A
Sbjct: 116 KLAQEVPEGATILIDDGRVEMRVEAVDPEAGELFCRTIVGGTLSNNKGVNFPGVRLSIRA 175

Query: 697 VS 702
           V+
Sbjct: 176 VT 177


>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
           organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
           NBC37-1)
          Length = 488

 Score =  105 bits (251), Expect = 1e-21
 Identities = 61/179 (34%), Positives = 98/179 (54%), Gaps = 2/179 (1%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II TIGPA+ +   ++ +M  G+N+ R+NFSHG+HEYH+E +   R+A +      G   
Sbjct: 7   IIATIGPATDSYEKIKALMCAGVNLFRLNFSHGTHEYHSEVLGRIRKAIEETGLITG--- 63

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSP--DYQEKGNADTIYVDYKNI 528
              I  D  GP+IR G+LE     +  LK G+ ++        Y+ K     + ++  +I
Sbjct: 64  ---ILQDISGPKIRVGMLE----EDFILKSGDILEFVKEEIVGYKVKEGVYRLCINEPDI 116

Query: 529 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            + ++ G  I++ DG+I  + +  SAD +   IEN GML SRKGVN P   + +  ++E
Sbjct: 117 LDQLEVGESIYMYDGIIRAVVKEKSADMVKVEIENNGMLSSRKGVNFPNTHLGINVLTE 175


>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
           Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
          Length = 591

 Score =  105 bits (251), Expect = 1e-21
 Identities = 64/184 (34%), Positives = 102/184 (55%), Gaps = 3/184 (1%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ TIGPA+++  VL ++++ G    R+NFSHG H YH ++IR  R+     + +L
Sbjct: 8   RRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQ----IAFEL 63

Query: 343 GSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
             P  + I  D +GP+IR G  L   GS  V+LK G+   LT+ P    +       + Y
Sbjct: 64  NQP--VGILQDLQGPKIRVGKFLNDAGS--VQLKNGDPYTLTSRP---VECTETISSISY 116

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLP 693
           + + + V  G RI +DDG + ++ + V   A  L C +  GG L S KGVN PG+ + + 
Sbjct: 117 EYLADEVPSGARILLDDGKLEMLVEEVDTVARDLHCRVIVGGTLSSNKGVNFPGVCLSVK 176

Query: 694 AVSE 705
           A+++
Sbjct: 177 AMTD 180


>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
           Pyruvate kinase - Flavobacteriales bacterium HTCC2170
          Length = 480

 Score =  104 bits (249), Expect = 2e-21
 Identities = 59/183 (32%), Positives = 101/183 (55%), Gaps = 1/183 (0%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           I+ + I+ T+GPA+    V+  M++ G++V R+NFSH  +E     ++  RE  +   + 
Sbjct: 4   IKKTKIVATLGPATSKKEVIIDMIKAGVDVFRINFSHADYEDVTARVKMIREVNEEIDS- 62

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
                ++AI  D +GP++R G++ G    EV +  G+ I   T   ++  GN++ +Y++Y
Sbjct: 63  -----NIAILGDLQGPKLRVGVMSG----EVVVTPGDEIDFVTGEPFE--GNSERVYMNY 111

Query: 520 KNITNVVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696
                 V PG RI +DDG L+  +  +   D +   +  GG L S+KGVNLP   + LPA
Sbjct: 112 AAFPKDVNPGERILLDDGKLMFEVVSTNKKDKVRAKVIQGGPLKSKKGVNLPNTNISLPA 171

Query: 697 VSE 705
           ++E
Sbjct: 172 LTE 174


>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
           Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
           longum
          Length = 509

 Score =  103 bits (248), Expect = 3e-21
 Identities = 59/189 (31%), Positives = 104/189 (55%), Gaps = 2/189 (1%)
 Frame = +1

Query: 145 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 324
           ++ +++R + I+ TIGP++ +   L K++E GM+VAR+N SHG+ E H +   N R+A +
Sbjct: 25  NRQAFMRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLKVYNNVRKASE 84

Query: 325 SYSAKLGSPFSLAIALDTKGPEIRTGLLE--GGGSAEVELKKGETIKLTTSPDYQEKGNA 498
           +         ++A  +D +GP+IR G  +    G  +V+L+ G+   +TT      +G+ 
Sbjct: 85  ATGR------NVAALVDLQGPKIRCGWFKKNADGEDKVQLQLGQEFVITTD---DVEGDE 135

Query: 499 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 678
                 +K +     PG+ I IDDG + +    V  + +   +   G + S KG+NLPG+
Sbjct: 136 HITSTTFKGLPGDCHPGDPILIDDGKVRLEVTKVEGNNVYTKVVVAGPVSSHKGINLPGV 195

Query: 679 PVDLPAVSE 705
            V LPA++E
Sbjct: 196 AVSLPALTE 204


>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
           cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
          Length = 519

 Score =  103 bits (248), Expect = 3e-21
 Identities = 62/176 (35%), Positives = 101/176 (57%), Gaps = 3/176 (1%)
 Frame = +1

Query: 166 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 345
           L+ I+CTIGP + +   ++++++ GM++AR+NFSHGS E H E IRN R+      ++ G
Sbjct: 96  LTKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRD------SRSG 149

Query: 346 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIK---LTTSPDYQEKGNADTIYVD 516
           +   ++IALDT+GPE+R   L      +++++ GE ++   L++  D    G      VD
Sbjct: 150 AGRHVSIALDTRGPEVR---LRTPEMKDIKVEGGEVLRFSLLSSEKDIWIPG------VD 200

Query: 517 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 684
            K++       NR+FIDDG I +   +V  D   C + N GM+ S K +N PG  +
Sbjct: 201 LKSL----GVDNRVFIDDGAIELRVVNVEEDGFECEVLNSGMIKSNKSMNFPGTDI 252


>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
           pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
           pacifica SIR-1
          Length = 485

 Score =  103 bits (247), Expect = 4e-21
 Identities = 61/182 (33%), Positives = 100/182 (54%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GPAS +  ++  +M+ G++  R+NFSHGSHE HA+     RE + S   +
Sbjct: 6   LRRAKILGTLGPASNSDEMIGALMDAGLDAVRLNFSHGSHEDHAQVYGKVRE-QSSIRRR 64

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
                 +A+  D +GP+IR G +   G   + L+ GET+   T P  +      TI  DY
Sbjct: 65  -----PVAVLGDLQGPKIRVGKIPDPG---MTLETGETLVFLTDPTAEISQGRVTI--DY 114

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
             +    K G R+ +DDG +      ++A  +   + NGG+L +RKGVNLP   + LP++
Sbjct: 115 PTLDEEAKVGERVLMDDGELEARITEINAGEVHAEMLNGGVLKARKGVNLPDSDLLLPSL 174

Query: 700 SE 705
           ++
Sbjct: 175 TD 176


>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
           Pyruvate kinase - Rhodopirellula baltica
          Length = 476

 Score =  102 bits (244), Expect = 1e-20
 Identities = 60/185 (32%), Positives = 97/185 (52%), Gaps = 4/185 (2%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + II TIGPA+ +   L  ++E G++V R+N +HG+ E+  E +   R+  K  S  +
Sbjct: 5   RHTKIIATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDISRHV 64

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSP----DYQEKGNADTIY 510
                 A+ +D KGPEIRTG +E      +ELK G+ + L T         E      + 
Sbjct: 65  ------AVMMDVKGPEIRTGAVEDA----IELKAGDELVLFTEDCADQSAVESDGTPRVS 114

Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690
           V+Y  +   +   + I +D GL+        A T+ C +   G+L SR+ +NLPG+ V+L
Sbjct: 115 VNYLGLPGAIDLDSTILVDSGLLHWHVLKKDATTVRCRVITPGVLESRRHINLPGVQVNL 174

Query: 691 PAVSE 705
           PA+++
Sbjct: 175 PAITD 179


>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
           MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
           MC-1)
          Length = 569

 Score =  101 bits (243), Expect = 1e-20
 Identities = 61/181 (33%), Positives = 93/181 (51%), Gaps = 1/181 (0%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ T+GPA  +V  + +++E G++VAR+N SHG H+ H E I N REA  S  AK 
Sbjct: 3   RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREA--SRIAKR 60

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY-VDY 519
                +A+  D +GP+IR G L+      + L+KG+   +     +  K   D I    Y
Sbjct: 61  ----EVALLCDLQGPKIRVGHLD----EPLRLEKGQQWAIIPEGSHPPKLKCDGIIPCTY 112

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
             +     PG RI  DDG +           L   IE+GG+L S KG+N+P   +  P++
Sbjct: 113 AGLAKDAVPGCRILFDDGYLQARAIGTEEGALLVNIEHGGLLKSHKGINMPDASISAPSL 172

Query: 700 S 702
           +
Sbjct: 173 T 173


>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
           pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
          Length = 507

 Score =  100 bits (240), Expect = 3e-20
 Identities = 57/188 (30%), Positives = 94/188 (50%)
 Frame = +1

Query: 142 DSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 321
           ++K    R + I+ T+GPAS +   +  + + G +V R+NFSHGSHE H +     R  E
Sbjct: 13  NTKMRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVE 72

Query: 322 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNAD 501
               A+ G P  + I  D +GP++R G    G    V LK G+   L   P     G+  
Sbjct: 73  ----AETGRP--IGILADMQGPKLRIGTFADG---RVVLKNGDRFVLDRDP---TPGDVT 120

Query: 502 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIP 681
            +++ +  +     PG  + +DDG I +  ++     +   + +GG L  RKGVN+P   
Sbjct: 121 RVHLPHPELYAATAPGQSLLLDDGKIRLAVEAADPTAIVTRVVDGGPLSDRKGVNVPDAV 180

Query: 682 VDLPAVSE 705
           + +PA++E
Sbjct: 181 IPIPALTE 188


>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
           Phytoplasma|Rep: Pyruvate kinase - Onion yellows
           phytoplasma
          Length = 446

 Score =  100 bits (239), Expect = 4e-20
 Identities = 61/178 (34%), Positives = 101/178 (56%), Gaps = 2/178 (1%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           IICT+GPAS +  +L+ +++TG+NVAR NFSH  +E     ++      K+ S KL    
Sbjct: 6   IICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTI----KTISDKLDK-- 59

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
           +  + LDTKGPEIRT   +G     V ++K   +K++ +   +  GNA    V Y N+ N
Sbjct: 60  NTGLMLDTKGPEIRTHEFDG----VVTIQKDSEVKISMT---EVLGNAKLFSVSYSNLYN 112

Query: 535 VVKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +K G+ + IDDG +S  ++ +  +   L    +N   + SR+GVN+P + +++  +S
Sbjct: 113 ELKVGDMVNIDDGYLSLEVVGKDEAKQQLVTKAKNTHSIKSRRGVNVPKVNLEMDFIS 170


>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
           araneosa HTCC2155
          Length = 485

 Score =  100 bits (239), Expect = 4e-20
 Identities = 59/178 (33%), Positives = 99/178 (55%), Gaps = 1/178 (0%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ T+GP ++    L++++E G++V R+NFSHGSHE HAE I+    A       +G   
Sbjct: 9   IVSTLGPTTKGR--LKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELKRTVG--- 63

Query: 355 SLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNIT 531
              I  D +GP+IR G ++EGG    ++L+ G+ + +TT     E     T++   + + 
Sbjct: 64  ---ILGDLQGPKIRCGKIIEGG----IQLEAGQELVITTDEILGEGSRISTVF---QALP 113

Query: 532 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
             VK G+ I +DDGL+  + + +  + + C +   G L S KG+NLP   +  PA++E
Sbjct: 114 REVKVGDPILMDDGLLEAVVERIEGNEIFCKMLVAGKLTSNKGINLPETDIQSPALTE 171


>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
           psychrophila|Rep: Pyruvate kinase - Desulfotalea
           psychrophila
          Length = 581

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 61/177 (34%), Positives = 97/177 (54%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II T+GP S++V  +  +++ GMNVAR+N SHG  E +   I N +EA K       +  
Sbjct: 6   IIATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEARKL------AEK 59

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
             AI LD +GPEIR   +E     ++ L  GE + +T   +  E  +   I  +Y  +  
Sbjct: 60  DTAILLDNRGPEIRVSEME----EDIHLVDGEELVIT---NRAETVSPSRITTNYPQLAG 112

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            V+ G+RI +DDG +++   ++  + +   +  GG+L SRK V LP   V+LP++SE
Sbjct: 113 DVQVGSRILLDDGKLALEVLAIEDEEVITKVIAGGILSSRKRVALPDNEVNLPSLSE 169


>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
           Pyruvate kinase - Methylobacterium extorquens
           (Protomonas extorquens)
          Length = 483

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 57/181 (31%), Positives = 95/181 (52%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ T+GPAS    ++EK+   G +V R+N SH + E   E I   R  E+     +
Sbjct: 10  RRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPI 69

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G      I +D +GP++R G   G  +    L+ G+T  L + P     G+ D +++ + 
Sbjct: 70  G------ILVDLQGPKLRLGTFVGDAAV---LENGQTFVLDSDPT---PGDTDRVFLPHP 117

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            I + ++P + I IDDG + +I   VS       +E GG + +RKGV+LP   + +PA++
Sbjct: 118 EILSALEPSHGILIDDGKLRLIVTEVSEGRAVTRVEVGGRISNRKGVSLPHTALPVPAMT 177

Query: 703 E 705
           E
Sbjct: 178 E 178


>UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania
           braziliensis|Rep: Pyruvate kinase - Leishmania
           braziliensis
          Length = 91

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 54/99 (54%), Positives = 72/99 (72%), Gaps = 1/99 (1%)
 Frame = +1

Query: 109 SQLQHMCGLDIDSKSSYIRLSG-IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEY 285
           SQL H   L I      +R +G I+CTIGP++++V  L+ ++++GM+VARMNFSHGSHEY
Sbjct: 2   SQLAHNLTLSIFEP---LRTTGTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEY 58

Query: 286 HAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 402
           H  TI N R+A    +A+LG   ++AIALDTKGPEIRTG
Sbjct: 59  HQTTINNVRQA----AAELG--VNIAIALDTKGPEIRTG 91


>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
           DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
           8797
          Length = 489

 Score = 96.3 bits (229), Expect = 6e-19
 Identities = 54/179 (30%), Positives = 101/179 (56%), Gaps = 2/179 (1%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II T+GPAS +  +L+K++  G+++ R+NF+HG HE+ +E ++N  E     SA++  P 
Sbjct: 17  IIATVGPASDSREMLQKLIIAGVDLFRLNFAHGKHEWLSEIVKNIHE----ISAEMEKP- 71

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            + I  D  GP+IR G+L G    E+  ++    +     D     N   +   Y+++  
Sbjct: 72  -IGILGDLSGPKIRLGVLPGD---EITCRQDMRFRFIQGLD---SDNPQELTCTYESLIG 124

Query: 535 VVKPGNRIFIDDGLISIICQSVSADT--LTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            ++ G+ + + DG++++     SAD   + C +E  G++ S++GVNLPG+ +  P ++E
Sbjct: 125 DLRVGDPVLLADGMVAMRVVEKSADDEFVECVVEREGIIRSKQGVNLPGVQLSTPCLTE 183


>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
           Epsilonproteobacteria|Rep: Pyruvate kinase -
           Nitratiruptor sp. (strain SB155-2)
          Length = 458

 Score = 95.9 bits (228), Expect = 9e-19
 Identities = 62/179 (34%), Positives = 99/179 (55%)
 Frame = +1

Query: 166 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 345
           ++ I+ TIGP+S  +  ++K++  G+NV R+NFSH  H+ H  +I+  RE  K    KLG
Sbjct: 1   MTKIVATIGPSS--IEKIDKLILAGVNVFRLNFSHADHKTHKASIKKIRETAK----KLG 54

Query: 346 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKN 525
           +    AI  D  GP+IR G ++G     +EL KG+ I+L  +     K   D + + Y  
Sbjct: 55  T--KTAILQDISGPKIRIGEVDG----ILELSKGDKIRLVKT---HPKSKYD-LTLSYPQ 104

Query: 526 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           I + ++ G  +F  DG I        +D++T  ++N G+L SRKGVN P   + L A++
Sbjct: 105 IIDDLEVGEYVFFADGTIRTKVIEKDSDSVTLLVKNPGVLSSRKGVNFPHSNLRLSAIT 163


>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
           eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
           eiseniae (strain EF01-2)
          Length = 496

 Score = 95.9 bits (228), Expect = 9e-19
 Identities = 59/171 (34%), Positives = 90/171 (52%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ T+GPAS   A+LE M+  G+NV R+NFSHG  + H +     R A +      
Sbjct: 23  RATKIVATLGPASSEPALLEAMIRAGVNVVRLNFSHGKAQDHIDRAACVRAAAQR----- 77

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
            +   +AI  D +GP+IR G    G    V L  G    L  S    E G+ D + +DYK
Sbjct: 78  -AGHEVAIMADLQGPKIRVGKFAEG---RVLLAPGAPFVLDAS--RTEPGDIDGVGLDYK 131

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG 675
            + + VK G+ + ++DGLI +   +V  + +  T++ GG L + KG+N  G
Sbjct: 132 ELPHDVKGGDLLLLNDGLIVLSVDAVRGEQVHTTVKIGGELSNNKGINKKG 182


>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
           Pyruvate kinase - Mycoplasma mobile
          Length = 483

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 65/179 (36%), Positives = 94/179 (52%)
 Frame = +1

Query: 169 SGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 348
           S +I TIGP+S+N  +L++MM  GM   R NFSHG    HAE + N     K  + +L  
Sbjct: 17  SKMIATIGPSSQNKEILKQMMLKGMTTVRANFSHGD---HAEQL-NKFVLAKEVAKELNL 72

Query: 349 PFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNI 528
           P SL   LDTKGPEIR G ++  GS ++E+ K  T+ LT    Y+      T +     +
Sbjct: 73  PMSL--MLDTKGPEIRVGKMK-DGSQKIEVGKIITV-LTDEVSYKTFEGIPTKFTVSHRM 128

Query: 529 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
              VK G+ I  DDG ++ I   V +  +     N  +L S K +N+PG  + L  +S+
Sbjct: 129 DKDVKVGSYILFDDGKLTTIVTGVKSGIVEVKTINSHVLKSNKRINIPGAQLSLEFLSK 187


>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
           Pyruvate kinase - Magnetococcus sp. (strain MC-1)
          Length = 483

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 56/182 (30%), Positives = 100/182 (54%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           IR + II T+GP + +   ++ +  TG++  R+NFSHGSHE H       R  E+    +
Sbjct: 4   IRRTKIIATLGPNASSRDFIKHLALTGVDTFRLNFSHGSHEDHRRRHGWIRSVEE----E 59

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           LG P  L I +D +GP++R G  E   ++EVEL +G+   L      +  G+ + + + +
Sbjct: 60  LGRP--LGIMMDLQGPKLRIGTFE---NSEVELVRGQKFALYKE---ERTGDINGVTLPH 111

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
             +  V++PG  + ++DG I++    V    + C +  GG+L  RKG+N+P   + + A+
Sbjct: 112 NELFQVMRPGLELLLNDGRINLRVMEVEDFGVCCEVRVGGILSDRKGLNVPAAMLPVKAL 171

Query: 700 SE 705
           ++
Sbjct: 172 TD 173


>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
           Pyruvate kinase - Bacteroides fragilis
          Length = 485

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 56/182 (30%), Positives = 93/182 (51%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           ++ + I+ +I     +V  ++++ + GMNV RMN +H S E     I N R         
Sbjct: 3   LKQTKIVASISDRRCDVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSNR---- 58

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
                 +AI +DTKGPE+RT       +  +  + GE +K+   PD +     + I V Y
Sbjct: 59  ------IAILMDTKGPEVRTT----ANADPILYQIGEKVKIVGDPDRET--TRECIAVSY 106

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
            N  + +  G  I IDDG + +     + + L C ++N   LGSRK VN+PG+ ++LP++
Sbjct: 107 PNFVHDLNVGGTILIDDGDLELRVIDKTTEYLLCEVQNEATLGSRKSVNVPGVRINLPSL 166

Query: 700 SE 705
           +E
Sbjct: 167 TE 168


>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
           Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
           pseudomallei)
          Length = 484

 Score = 93.1 bits (221), Expect = 6e-18
 Identities = 53/180 (29%), Positives = 95/180 (52%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ T+GP+S     +E +   G +V R+NFSHG+H  HA  +R+   A ++  A++
Sbjct: 13  RSTKIVATLGPSSSTETAIEALARAGADVFRLNFSHGTHADHA--LRHA--AVRAIEARI 68

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G P  + + LD +GP++R G    G     ++ KG        P     G+A  + + + 
Sbjct: 69  GHP--IGVLLDLQGPKLRVGQFASG---RAQIAKGRPFVFDRDP---APGDARRVSLPHP 120

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            I +  +PG+ + +DDG +     +VS+  +  T    G++  RKGV++P   + +PA+S
Sbjct: 121 EIFDAARPGHLLLVDDGKLRFRVDAVSSARIETTALLDGIVSDRKGVSVPDATLAIPALS 180


>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
           organisms|Rep: Pyruvate kinase - Phaeodactylum
           tricornutum
          Length = 665

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 53/165 (32%), Positives = 85/165 (51%)
 Frame = +1

Query: 178 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 357
           + T+GPAS N  ++EK+   G +V R+NFSHGS E   E +   RE E+ YS  +G    
Sbjct: 158 VVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYSHPIG---- 213

Query: 358 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNV 537
             I  D +GP++R G         +EL  G++ +L        KG+   + + +  I   
Sbjct: 214 --ILGDLQGPKLRVGEFSKPEGEFLEL--GQSFRLDLD---NAKGDNKRVQLPHPEIIKA 266

Query: 538 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 672
            + G+ + +DDG + ++  +   D L C ++  GM+  RKGVN P
Sbjct: 267 SELGHALLVDDGKVKLVVTAKGDDYLECRVDVAGMIKDRKGVNTP 311


>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
           Pyruvate kinase - Thermotoga maritima
          Length = 466

 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 56/182 (30%), Positives = 98/182 (53%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+CT+GP + +  ++EKM++ G+NV R+N SHG      + I   ++  +    K
Sbjct: 1   MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLRE----K 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
              P  +AI +D  GP+IRTG LE      VELK+G+   LTT    +  GN   + V+ 
Sbjct: 57  KKKP--VAILIDLAGPKIRTGYLE---KEFVELKEGQIFTLTTK---EILGNEHIVSVNL 108

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
            ++   VK G+ I + DG I +     +   +   ++ GG +  R+GVN+P   + + ++
Sbjct: 109 SSLPKDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPTADLSVESI 168

Query: 700 SE 705
           ++
Sbjct: 169 TD 170


>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
           pernix|Rep: Pyruvate kinase - Aeropyrum pernix
          Length = 458

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 56/176 (31%), Positives = 95/176 (53%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ T+GP+S + ++L +M+  G++VAR+N SHG  E     + + R AE++   ++G   
Sbjct: 7   IVATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVG--- 63

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
              +A+D +GP +RT     G S  V+L+KG+ + L     + E      + VD +    
Sbjct: 64  ---VAVDLEGPRVRT-----GNSEPVKLEKGDLVTL----GFME----GDVPVDARQFFE 107

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +  G+ + +DDG I +  +SV    +   +  GG+LG RKGV + G   DLP +S
Sbjct: 108 TIDEGDIVLLDDGKIILQVESVEGFRVKARVLEGGVLGPRKGVVVRGKEPDLPPLS 163


>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
           organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
           (Lyme disease spirochete)
          Length = 477

 Score = 89.4 bits (212), Expect = 7e-17
 Identities = 55/181 (30%), Positives = 93/181 (51%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           +L+ I+ TI         ++ + + G+NV R+N +H SHE   + I N R+         
Sbjct: 4   KLTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQSHEDTIKVIDNVRKISNK----- 58

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
                +A+ +DTKGPE+RT  +E      + +K G+ + ++TSP   E  N  T   +Y 
Sbjct: 59  -----IALMIDTKGPEVRTANIEN----PIIVKTGDKVIISTSP-INEPNNFQT---NYD 105

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
                V  G+++ IDDG + +   +   D L C I+N G + ++K +N PGI + L +V+
Sbjct: 106 GFVKEVPQGSKVLIDDGELEMTVVAKLPDRLICEIKNDGQIKNKKSINTPGISLKLQSVT 165

Query: 703 E 705
           E
Sbjct: 166 E 166


>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
           50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
          Length = 553

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 52/180 (28%), Positives = 93/180 (51%), Gaps = 2/180 (1%)
 Frame = +1

Query: 139 IDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA 318
           +D    +     I CT+GP+S NV V+  M+  G ++ R+NFSHG+ + H +     ++A
Sbjct: 30  VDKNHPHFNRVKICCTLGPSSFNVEVIAGMIRAGADIIRINFSHGNTDDHTQIFHKVQQA 89

Query: 319 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNA 498
               + K     ++AI  D +GP++R        +  +ELK+G+   L  +      G+ 
Sbjct: 90  -MQLTGK-----TVAIMGDIQGPKLRIAGFSNPDNC-IELKEGQEFTLDHN---NVNGDE 139

Query: 499 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLP 672
             +Y+ +K    V +P + I ++DG I ++  SV   A  +   ++ GG LG+RKG+ +P
Sbjct: 140 SRVYLPHKEFFAVCEPNDDIILNDGYIRLVATSVDRQAMRIVTRVKTGGKLGARKGITIP 199


>UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate
           kinase isozyme M2; n=4; Rattus norvegicus|Rep:
           PREDICTED: similar to Pyruvate kinase isozyme M2 -
           Rattus norvegicus
          Length = 123

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 44/89 (49%), Positives = 62/89 (69%)
 Frame = +1

Query: 115 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 294
           L+HMC L+IDS       +GIICTIG   ++V +L+ M+ +GMNVA +NFSHG+HEYHAE
Sbjct: 27  LEHMCCLEIDSAPIMAHNTGIICTIG---QSVEMLKGMIMSGMNVAHLNFSHGTHEYHAE 83

Query: 295 TIRNCREAEKSYSAKLGSPFSLAIALDTK 381
           TI+N     +S+++      S+ +ALDTK
Sbjct: 84  TIKNVCATTESFASDPILYLSIVVALDTK 112


>UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma
           japonicum|Rep: Pyruvate kinase - Schistosoma japonicum
           (Blood fluke)
          Length = 168

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 44/136 (32%), Positives = 80/136 (58%)
 Frame = +1

Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288
           S +QH+    ID    ++R + ++CT+G    +   +++M+++GMN+ R+N S G+ E +
Sbjct: 25  SLMQHISNQSIDHAPFFVRHTNLVCTLGDHWDSDEKIDQMIKSGMNILRLNLSMGTKEKY 84

Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468
           AE IR  R  E+SY     +P S+ IALD   P +RTGL+     A V ++ G+ + LT 
Sbjct: 85  AEVIRRVRRLEESYDY---NP-SVGIALDLSAPPVRTGLINESVDAVVVIQTGQMVTLTI 140

Query: 469 SPDYQEKGNADTIYVD 516
           + +Y++   +  I+++
Sbjct: 141 NDEYEKNTTSSIIWIN 156


>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
           Proteobacteria|Rep: Pyruvate kinase II - Salmonella
           typhimurium
          Length = 480

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 62/185 (33%), Positives = 94/185 (50%)
 Frame = +1

Query: 151 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 330
           S  +R + I+ T+GPA+     LEK++  G NV RMNFSHGS E H       RE     
Sbjct: 2   SRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVRE----I 57

Query: 331 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY 510
           +AKLG    +AI  D +GP+IR    + G   +V L  G+   L  +    E G+ + + 
Sbjct: 58  AAKLGR--HVAILGDLQGPKIRVSTFKEG---KVFLNIGDKFLLDANLGKGE-GDKEKVG 111

Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690
           +DYK +   V PG+ + +DDG + +    V    +   +  GG L + KG+N  G  +  
Sbjct: 112 IDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSA 171

Query: 691 PAVSE 705
            A++E
Sbjct: 172 EALTE 176


>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
           Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
           Candidatus Desulfococcus oleovorans Hxd3
          Length = 478

 Score = 86.2 bits (204), Expect = 7e-16
 Identities = 52/180 (28%), Positives = 93/180 (51%), Gaps = 4/180 (2%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           +I TIGP SR+ AV+EK++  G+ + R+NFSH      A+ I++ RE E+          
Sbjct: 5   LIATIGPRSRDRAVIEKLVAVGVTIFRLNFSHAGPGDFADVIQSVREIEQQTGT------ 58

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            L +  D  GP+IR G + G   A + +  G+ ++L  +      G+A  + ++   I  
Sbjct: 59  ILTLMGDLSGPKIRIGEVAG---APLSVATGQLVRLGPARAKGAFGDALYLPLELAEILE 115

Query: 535 VVKPGNRIFIDDGL----ISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +KPG  + + DG+    +     + +        +N G++ S KG++ PG+ +DLPA++
Sbjct: 116 QLKPGAPVILSDGIPVFRVRKRLDTEAGPVFELETQNSGLVSSNKGISFPGLAIDLPALT 175


>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 1010

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 42/95 (44%), Positives = 59/95 (62%)
 Frame = +1

Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288
           SQL +   L   + +  + L+ IICTIGP+S    VL  ++  GM V R++FS G+H+ H
Sbjct: 165 SQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCH 224

Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEI 393
            + I+  R+A   Y+ + G P SLAIALDTKGP I
Sbjct: 225 CQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVI 259


>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
           Pyruvate kinase - Mesoplasma florum (Acholeplasma
           florum)
          Length = 478

 Score = 84.2 bits (199), Expect = 3e-15
 Identities = 54/182 (29%), Positives = 89/182 (48%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           ++ + II T GP++     + ++ E GM   R+NFSHG +E     I   ++  +    +
Sbjct: 10  VKRTKIITTTGPSTNEPEQIRELFENGMTTIRLNFSHGDYEEQGYRIAGAKKVRE----E 65

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           LG P S  I LDTKGPEIR G     G  EV   +  TI  T +  ++ K          
Sbjct: 66  LGKPVS--ILLDTKGPEIRVGKFV-DGKQEVTANQSITI-YTDAESFKNKECLSGEMTVA 121

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
            +++  +K G+ I IDDG + +  + V    +     N  ++ + K VNLPG+   +P +
Sbjct: 122 YDMSVDLKIGDTILIDDGKLEMTVEEVKPGVVKAIAFNNHLVKTNKRVNLPGVDFSMPFL 181

Query: 700 SE 705
           ++
Sbjct: 182 AQ 183


>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
           precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
           isozyme A, chloroplast precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 593

 Score = 84.2 bits (199), Expect = 3e-15
 Identities = 53/162 (32%), Positives = 81/162 (50%), Gaps = 1/162 (0%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + +ICTIGPA+     LE++ E GMNVAR+N  HG+ E+H   I   R   +      
Sbjct: 114 RRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEE----- 168

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
              F++AI +DT+G EI  G L G  SA+ E   GE    T    +       T+ V+Y 
Sbjct: 169 -KGFAVAIMMDTEGSEIHMGDLGGASSAKAE--DGEIWNFTVR-SFDPPLPERTVTVNYD 224

Query: 523 NITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 645
                VK G+ + +D G++   + + +  D + C   + G+L
Sbjct: 225 GFAEDVKVGDELLVDGGMVRFEVIEKIGPD-VKCLCTDPGLL 265


>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
           ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 474

 Score = 83.8 bits (198), Expect = 4e-15
 Identities = 58/178 (32%), Positives = 90/178 (50%), Gaps = 1/178 (0%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ T+GP SR+   +  + E G++V R+NFSHG H  H E ++  R AE    A +G P 
Sbjct: 13  IVATLGPGSRSPREVRALAEAGVDVFRLNFSHGEHAAHLEALKAVRAAE----AAVGWP- 67

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            LA   D +GP++R G  +GG       K+   I   T+PD       +TI V +  I  
Sbjct: 68  -LATLADLQGPKVRVGKFDGGSLKLGFRKEYRIIVGETAPD------PETIPVPHAEIVA 120

Query: 535 VVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           +++ G+ I  DDG LI  +    S   +   +   G LG +KG  + G  + + A++E
Sbjct: 121 ILEEGDTILADDGKLIFTVISGGSEPRVRAEVP--GKLGDKKGFTVRGKALPVRALTE 176


>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
           Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 471

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 53/178 (29%), Positives = 89/178 (50%), Gaps = 1/178 (0%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II TIGPAS +   L ++++ G+++ R+NFSHG      E I   RE E  +        
Sbjct: 5   IIATIGPASNSKETLSQLIQAGVSIFRLNFSHGDSSAFIELISTIRELEHIHQ------I 58

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            + I  D  GP+IR G L   G   + + KG+ + L   P+ +   +   I  D+K I +
Sbjct: 59  PITIMQDLSGPKIRIGALP--GDVALNVSKGDVLCL--GPEDKRTNDYPYIPFDHKAILS 114

Query: 535 VVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            +   + + + DG +   + +  S  T     +  G++ SRKG+ LPG  + +PA++E
Sbjct: 115 DLVVNDILILADGTLQFQVKEQNSNGTFLLIAQEDGIITSRKGLALPGKSIKVPAITE 172


>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
           CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
          Length = 485

 Score = 82.6 bits (195), Expect = 9e-15
 Identities = 54/178 (30%), Positives = 95/178 (53%), Gaps = 2/178 (1%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II T+GPAS++  ++ K++  G+N+ R+NFSHGS + H +    C +  +  SA+LG   
Sbjct: 6   IIATLGPASQSEDMIRKLILAGVNIVRLNFSHGSAQEHID----CAKLVRRISAELGK-- 59

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            + + +D +GP+IR    +   +  VEL  G+   L      +  G+   + + Y ++  
Sbjct: 60  YVGVLVDLQGPKIRIACFK---NDVVELVAGQRFVLDAKL-AEFDGSVSAVGLGYPDLIA 115

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTL--TCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +   + + +DDG I +    VS + L  T  + N G L +RKG+NL G  +  PA++
Sbjct: 116 DLNIDDVLLLDDGRIHLQVTEVSKEELKVTTKVLNSGKLSNRKGINLLGGGLSAPALT 173


>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
           marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
           marina DSM 3645
          Length = 490

 Score = 82.6 bits (195), Expect = 9e-15
 Identities = 52/176 (29%), Positives = 91/176 (51%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ T+GPA     +LE+M+  G++V R+N +HG  + H+      RE     S +L  P 
Sbjct: 15  IVATVGPACNTPEMLEQMILAGVDVFRLNLAHGELDEHSRVATTIREI----SERLKRP- 69

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            +A   D  GP+IR G L       VE +    I+   + +  E      +  +Y+ + +
Sbjct: 70  -VATLADLSGPKIRLGTLVQDPIYCVEEQMYRFIRGDVATEPNE------LVSNYEPLID 122

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            VK G+ + + DG I++     + D++TC +  GG+L SR+G+NLPG  + +  ++
Sbjct: 123 EVKVGDNVMLADGTITMEVVEKTEDSVTCVVVAGGILRSRQGINLPGTKLGVETIT 178


>UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca
           wickerhamii|Rep: Pyruvate kinase - Prototheca
           wickerhamii
          Length = 259

 Score = 82.6 bits (195), Expect = 9e-15
 Identities = 53/147 (36%), Positives = 83/147 (56%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R +  +CTIGP S +     ++ + GMNV R+N SHG H  H + I   RE    Y+A L
Sbjct: 100 RKTKTVCTIGPTSCDREAFFRLADAGMNVVRLNMSHGDHASHQQVIDLVRE----YNA-L 154

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G   +LAI LDTKGPE+R+G L    +  ++L+KG+ I  T        G  + I V+Y 
Sbjct: 155 GRR-NLAIMLDTKGPEVRSGDL----TQPLDLEKGDLITFTIVAG--ADGTNNRIGVNYD 207

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVS 603
              + V+ G+ + +D G+++++ +S S
Sbjct: 208 GFIDDVEVGDMLLVDGGIMTMLVKSKS 234


>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
           pneumophila|Rep: Pyruvate kinase II - Legionella
           pneumophila subsp. pneumophila (strain Philadelphia 1
           /ATCC 33152 / DSM 7513)
          Length = 474

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 53/173 (30%), Positives = 89/173 (51%), Gaps = 1/173 (0%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GPAS+   +L  M+  G+NV R+NFSH       + I   R+     + +
Sbjct: 2   LRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADSSA-LQLIALVRKI----ADE 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT-SPDYQEKGNADTIYVD 516
           L  P  +A+  D +GP+IR G  +   +  + L  G+   L   +PD    G+ + + V 
Sbjct: 57  LNHP--VAVMADLQGPKIRVGRFQ---NKSITLIDGQNFTLDCMAPD--TLGDINGVSVA 109

Query: 517 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG 675
           Y N+ N +  G+ + I+DGLI +    +S   + C +  GG+L   KG+N  G
Sbjct: 110 YPNLANELSIGDHLLINDGLIELEVIEISGSKIHCKVVEGGVLTDLKGLNRKG 162


>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
           persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
           Endoriftia persephone 'Hot96_1+Hot96_2'
          Length = 246

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 49/181 (27%), Positives = 91/181 (50%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ T+GPA+ +  V++K++  G++V R+N SH  H+   E     R+  ++   ++
Sbjct: 36  RRTKIVATLGPATDDPKVMDKLIHAGVDVVRLNLSHDPHDQQRERAERIRDRSRASGRQV 95

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G      +  D +GP+IR G  +   S  V L++     L       + G+ + + + Y 
Sbjct: 96  G------VLCDLQGPKIRIGRFK---SDFVMLEEDGAFILDAECPLTD-GDDERVGLTYP 145

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           ++ N V  G+ + +DDG I +    V    + C +  GG L + KG+N  G  +  PA++
Sbjct: 146 DLINDVARGDTLLLDDGAIVLWIAEVEGKQVHCKVVVGGKLSNNKGINKQGGGLSAPALT 205

Query: 703 E 705
           E
Sbjct: 206 E 206


>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 527

 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 10/197 (5%)
 Frame = +1

Query: 145 SKSSYI-RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 321
           SKSS+   L+ I+ T+GP SR+V  L   ++ GM+VAR +FS G  +YH ET+ N + A 
Sbjct: 21  SKSSFFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSWGDADYHQETLDNLKVAV 80

Query: 322 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNAD 501
           +S + KL      A+ LDT GPE++   +       + LK    + LT  P+  ++ +++
Sbjct: 81  RS-TKKL-----CAVMLDTVGPELQ---VINKSEKAITLKADGLVTLT--PNQDQEASSE 129

Query: 502 TIYVDYKNITNVVKPGNRIFIDDGLIS--------IICQSVSADTLTCTIENGGML-GSR 654
            + +++  +   VK G+ IF+   L +        +    V  D + C   N   L GS 
Sbjct: 130 VLPINFNGLAKAVKKGDTIFVGQYLFTGSETTSVWLEVDEVKGDDVICLSRNAATLAGSL 189

Query: 655 KGVNLPGIPVDLPAVSE 705
             ++   + +DLP ++E
Sbjct: 190 FTLHSSQVHIDLPTLTE 206


>UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium berghei|Rep: Putative uncharacterized protein
           - Plasmodium berghei
          Length = 158

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 47/123 (38%), Positives = 68/123 (55%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+CT+GPA ++V  L ++++ GM++ R NFSHG+H+ H +   N  +A+           
Sbjct: 41  IVCTLGPACKSVETLVQLIDAGMDICRFNFSHGTHDDH-KMFENVLKAQAQ-----RPNC 94

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
           +L + LD KGPEIRTGLL   G+ E  LK+G  +KL    DY   G+   I   Y   T 
Sbjct: 95  TLGMLLDNKGPEIRTGLL---GNKEAHLKEGSKLKLVA--DYSYLGDETCIACSYTKCTT 149

Query: 535 VVK 543
             K
Sbjct: 150 KCK 152


>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
           Babesia bovis|Rep: Pyruvate kinase family protein -
           Babesia bovis
          Length = 693

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 57/203 (28%), Positives = 99/203 (48%), Gaps = 17/203 (8%)
 Frame = +1

Query: 148 KSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS 327
           +  ++ L+  + T+GP++     L  +ME G ++ R+NFSHG+  +     R  R+ E  
Sbjct: 105 QGQFMTLTKQVSTLGPSTCTADSLRSIMEAGTDIYRLNFSHGTRLFKLRLTRMIRQLELV 164

Query: 328 YSAKLGSPFSL----AIALDTKGPEIRTGL-----------LEGGGSAEVELKKGETIKL 462
            S+  GS   +     I  D +GP++R G            +E   +  VELKKG+    
Sbjct: 165 RSSGEGSDSFMVSPKGILGDIQGPKLRIGRFMPNVDAVGKGIESSAAEFVELKKGDKFTF 224

Query: 463 TTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENG 636
            T   +  KG+   +  ++ +I   +  GN I +DDG +++   SV  D  ++T  + N 
Sbjct: 225 DT---HDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNLEVISVDRDAPSVTAVVLND 281

Query: 637 GMLGSRKGVNLPGIPVDLPAVSE 705
           G+L SRKG  +P + + +   SE
Sbjct: 282 GVLSSRKGFAVPNVAITVDLFSE 304


>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
           Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
           lactis subsp. lactis (Streptococcus lactis)
          Length = 502

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 55/173 (31%), Positives = 84/173 (48%), Gaps = 3/173 (1%)
 Frame = +1

Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375
           +++N+A L   +E G NV R NFSHG H      +     AE+    K+G        LD
Sbjct: 38  SAKNIAAL---IEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVG------FLLD 88

Query: 376 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYV-DYKNITNVVKPGN 552
           TKGPE+RT L   G  A + +  G+  ++ T    +       + V    +I + V+ G 
Sbjct: 89  TKGPEMRTELFADGADA-ISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQ 147

Query: 553 RIFIDDGLISIICQSVSADTLTCTIE--NGGMLGSRKGVNLPGIPVDLPAVSE 705
            I IDDG + +      A T    +E  N G++G +KGVN+P   +  PA++E
Sbjct: 148 TILIDDGKLGLSLTGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAE 200


>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
           Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
           fastidiosa
          Length = 501

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 53/181 (29%), Positives = 86/181 (47%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+ T+GPA+    VL+ + + G+NV R+NFSHG     A      R A      ++
Sbjct: 19  RRTRILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDASDQARRAAEVRAAAAHVGVEI 78

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G      I  D  GP+IR G    G    V   + + +  + +P     G+A  + V Y 
Sbjct: 79  G------ILADLPGPKIRIGRFTEGKVRLVADARFDLLADSNAP----LGDATQVGVSYL 128

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            +   V  G+ + +DDGL+ +    V    +  T+ N G+L  RKG+N  G  + L A++
Sbjct: 129 GLPQDVAAGDVLLLDDGLMQLQVVQVQGARIVTTVLNDGVLSDRKGLNKQGGGLSLGALT 188

Query: 703 E 705
           +
Sbjct: 189 D 189


>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr2 scaffold_11, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 475

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 46/147 (31%), Positives = 81/147 (55%)
 Frame = +1

Query: 265 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 444
           SHG H  H +TI   +E    +  K+     +AI LDTKGPE+R+G +       + LK+
Sbjct: 2   SHGDHASHKKTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVRSGDVP----KPIMLKE 52

Query: 445 GETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 624
           G+    T       +   +T+ V+Y +  N V+ G+ + +D G++S++ +S S D + C 
Sbjct: 53  GQEFNFTIKRGVSSE---NTVSVNYDDFVNDVEVGDILLVDGGMMSLVVKSKSKDLVKCQ 109

Query: 625 IENGGMLGSRKGVNLPGIPVDLPAVSE 705
           + +GG L SR+ +N+ G    LP++++
Sbjct: 110 VIDGGELKSRRHLNVRGKSATLPSITD 136


>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
           hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
           hungatei (strain JF-1 / DSM 864)
          Length = 500

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 54/181 (29%), Positives = 94/181 (51%)
 Frame = +1

Query: 151 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 330
           S  +R + II TIGPAS N  ++ +M+ +GM++AR+N SHGS  +H ET++  R      
Sbjct: 29  SCTMRRTKIIATIGPASSNPRIIREMILSGMDIARLNLSHGSPPWHEETVQQIRALADEL 88

Query: 331 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY 510
           + ++G      I +D  GP++R  L+    S   ++  G+TI +    ++     +  I+
Sbjct: 89  NREIG------ILVDIPGPKLRV-LIH---SPPRDVVPGDTIHIAAEHEHA----SGAIH 134

Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690
           V   +    V PG+ + + DG +++         LT T+ +GG +    GV +PG   D+
Sbjct: 135 VHPPDCIPKVCPGDVVLVGDGAVTLQVLKPGPPMLT-TVISGGTIREGMGVVIPGRRPDV 193

Query: 691 P 693
           P
Sbjct: 194 P 194


>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
           Pyruvate kinase - Chromobacterium violaceum
          Length = 468

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 47/181 (25%), Positives = 89/181 (49%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GP+S     + ++  +G+N+ R+N SHGSH+ H   +   R AEK+    
Sbjct: 2   LRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTLDRP 61

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           +G      + +D +GP++R G           +K G+  +       + +GNA+   + +
Sbjct: 62  IG------VLVDLQGPKLRIGKF----PQPTTVKTGDRYEFVLD---ETEGNAERATLPH 108

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
                 ++PG+ I ++DG ++     +    +   +  GG L S KG NLP   + L A+
Sbjct: 109 PEAFEALEPGHLILVNDGKLAFEVAEMHPRRIVTRVTVGGELSSNKGFNLPHTVLPLSAI 168

Query: 700 S 702
           +
Sbjct: 169 T 169


>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
           Pyruvate kinase - Mycoplasma pneumoniae
          Length = 508

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 53/167 (31%), Positives = 84/167 (50%), Gaps = 3/167 (1%)
 Frame = +1

Query: 211 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPE 390
           A +E +++ G+ V R+NFSHG+HE  A  I+  R+  K    KL  P S  I LDT GPE
Sbjct: 42  ANIENIIKNGVTVIRLNFSHGNHEEQAVRIKIVRDVAK----KLNLPVS--IMLDTNGPE 95

Query: 391 IRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVD-YKNITNVVKPGNRIFID 567
           IR  + E        LK  E +  TT+ +  +             N+ N VK G +I +D
Sbjct: 96  IR--VFETAPEGLKILKDSEVVINTTTKEVAKNNQFSVSDASGTYNMVNDVKVGQKILVD 153

Query: 568 DGLISIICQSVSA--DTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           DG +S++ + +    + + C  +N   + ++K +NLP     +P +S
Sbjct: 154 DGKLSLVVKRIDTKNNQVICVAQNDHTIFTKKRLNLPNADYSIPFLS 200


>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
           Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
           eutropha (strain C71)
          Length = 483

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 51/167 (30%), Positives = 81/167 (48%), Gaps = 1/167 (0%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGM-NVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSP 351
           IICT+GPA+    VL +++  GM +VAR N SHG H  HA  I+  R+      A+    
Sbjct: 19  IICTLGPATDQPGVLARLIGAGMMDVARFNLSHGDHASHARRIQQVRQL-----AQQAGR 73

Query: 352 FSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNIT 531
           F +A+ +D  GP+ R G L  G     EL  G  + L    D       D + V +  + 
Sbjct: 74  F-IAVLMDLPGPKFRLGELSNGAR---ELHLGADVILALEAD-----PPDGLPVKHPALL 124

Query: 532 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 672
             ++ G  +++ DG I +  +   A+ + C +   G + S  G+N+P
Sbjct: 125 QALRVGESVYLADGAIRLEVKIAGAERVVCQVLVSGTVTSGSGINVP 171


>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
           Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
          Length = 745

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 58/189 (30%), Positives = 87/189 (46%), Gaps = 13/189 (6%)
 Frame = +1

Query: 178 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 357
           I TIGPAS N   LEK+   G++V R+NFSHG        I + R  EK Y   +G    
Sbjct: 102 IATIGPASENFEQLEKLYLNGIDVFRLNFSHGLKSIKKYIINSIRILEKKYDTTIG---- 157

Query: 358 LAIALDTKGPEIRTG------LLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
             I  D +GP+IR G      + E   +  VELK+G+             GN + + ++Y
Sbjct: 158 --ILGDIQGPKIRIGEFEKNQINENDNNTFVELKEGDLFSFDL---MNSLGNQNRVQLNY 212

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADT-------LTCTIENGGMLGSRKGVNLPGI 678
             +    K G  I +DDG + +     + DT       +   +  GG L S+KG  +P +
Sbjct: 213 PELIKNAKAGQIILLDDGNLKMKILENNYDTSNIQNSYIKVQVLTGGKLYSKKGFCIPNM 272

Query: 679 PVDLPAVSE 705
            + +  +SE
Sbjct: 273 IMPIDVLSE 281


>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
           marinus F1|Rep: Pyruvate kinase - Staphylothermus
           marinus (strain ATCC 43588 / DSM 3639 / F1)
          Length = 469

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 51/177 (28%), Positives = 89/177 (50%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II TIGP+S    VL ++++ G++  R+NFSHG+     E ++  RE  + Y  +     
Sbjct: 6   IITTIGPSSGKYEVLSRLIQEGVDGFRINFSHGNPHEWDEWVKMVRELAEKYERE----- 60

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            ++I  D  GP++R G L        E+K  +T+KL       E+   +TI V  + +  
Sbjct: 61  -ISIMGDLPGPQVRIGEL-----PVQEIKAKQTVKLVYKDKVDEE---NTIPVPNRKVFE 111

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           +++ G+ + IDDG I +    +  +     + N  +L   K + + G  +DLP +SE
Sbjct: 112 ILELGDIVLIDDGKIILRIIDIGGNEAEAIVLNDAVLYPHKTLVVFGKEIDLPVLSE 168


>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
           penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
          Length = 498

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 55/179 (30%), Positives = 85/179 (47%), Gaps = 6/179 (3%)
 Frame = +1

Query: 187 IGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAI 366
           I  A +N+A L    + G+NV R NFSHG +E     +   RE  K          +++ 
Sbjct: 36  IETAKKNLAAL---FDAGVNVVRFNFSHGDYEEQTIRLNLVREVAKEKGV------NIST 86

Query: 367 ALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYV----DYKNITN 534
            LDTKGPEIR   +      EVE+K    +++ T+   +E G ++   V       N+  
Sbjct: 87  MLDTKGPEIR---VYKTSEKEVEIKSDSKVRIYTTK--KEIGTSEKFSVLDSTGTYNMAK 141

Query: 535 VVKPGNRIFIDDG--LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            V+PGN IF+DDG   + +I  +V    +     N  +L   K +NLP     +P +S+
Sbjct: 142 DVQPGNTIFVDDGKLKLEVISSNVEEGIIETIARNTWILRENKRINLPDSNYSIPFMSD 200


>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
           Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
           torridus
          Length = 555

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 49/167 (29%), Positives = 83/167 (49%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           +I TIGPAS ++ +++KM   G++  R+N +H  + Y  +  +   +  KS    +G   
Sbjct: 6   LIATIGPASESMEIIKKMANLGLSCIRINTAHIENGYITKVAKMVDDVNKSEGTYIG--- 62

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
              + +D KGPE+RTG  +  GS +++  K   I       Y +  N D I ++Y NI++
Sbjct: 63  ---LMVDLKGPELRTGKFK-DGSFKIDYNKKYKI------SYNKNDNPD-ILINY-NISD 110

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG 675
            +     I + DG +     SV+ D +  T  + G L     VN+PG
Sbjct: 111 FIDDKTLIAMSDGKLRFSVDSVNGDIINVTSLDSGSLRDNSRVNVPG 157


>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
           Pyruvate kinase - Thermoplasma acidophilum
          Length = 544

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 50/177 (28%), Positives = 91/177 (51%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ TIGPAS +  ++++M++ G+++ R+N +H       + +    +  +S +  +G   
Sbjct: 5   IVATIGPASSSPEIMKQMIDNGLSLVRINSAHAD----IKDVSKITQMVRSINRDVG--- 57

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
              I +D KGPE+RTG   GG           T+K+++  DY        I ++  N+ +
Sbjct: 58  ---IMIDLKGPELRTGEFAGG-----------TLKISSGKDYV---MGKDIVLNNMNVLS 100

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            V+ G+RI + DG +S   +  S D  T    N G+L  R  VN+PG  ++L  +++
Sbjct: 101 AVQVGDRILMSDGEVSF--EVESTDPFTIRALNDGVLRDRSRVNIPGRFIELGTITD 155


>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
           Pyruvate kinase - Theileria parva
          Length = 699

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 57/201 (28%), Positives = 100/201 (49%), Gaps = 19/201 (9%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSH-EYH--AETIR--NCREAEK 324
           + L+  + T+GPA+ N   ++ + + G++V R+NFSH S    H  ++TIR     E  K
Sbjct: 116 LTLTKQVATLGPATNNAESIKSLFDAGVDVFRLNFSHDSRLSKHLVSKTIRQLEINEPPK 175

Query: 325 SYSAKLGSPFS-LAIALDTKGPEIR----------TGLLEGGGSAE-VELKKGETIKLTT 468
           +Y           +I  D +GP++R           G+L G    E VELK G+   L T
Sbjct: 176 NYPFNGDHVVEHKSILGDIQGPKLRIGKFMPNLDVPGVLPGSKGCEFVELKAGD---LFT 232

Query: 469 SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGM 642
              Y   G+   + +D+  I   +K G++I +DDG +S  ++  +    ++T  ++N   
Sbjct: 233 FDAYDVLGSKSRVQLDFPEILKELKVGDKILLDDGNLSMTVVKTNPEEPSVTAEVKNDYK 292

Query: 643 LGSRKGVNLPGIPVDLPAVSE 705
           L SRKG ++P + + +  + E
Sbjct: 293 LSSRKGFSVPKVVLPIEFLDE 313


>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr3 scaffold_95, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 573

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 43/162 (26%), Positives = 82/162 (50%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + ++CTIGPA   +  LE +  +GMNVAR+N  H + E+H + IR  +   +     
Sbjct: 87  MRKTKLVCTIGPACCLLEDLENLASSGMNVARLNMCHNTWEWHRDVIRKIKRLNEE---- 142

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
               + +++ +DT+G +I   +++ G    V+  + E+I L T+  + E     T+  +Y
Sbjct: 143 --KGYCVSVMIDTEGGQIH--VVDHGAPFSVK-AENESIWLFTTQKF-EGSRPFTVQANY 196

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 645
           +  +  +  G+ + ID G+ S        + L C   + G+L
Sbjct: 197 EGFSEGITVGDEVVIDGGMASFEVIEKIGNDLRCKCTDPGLL 238


>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
           butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
           butylicus (strain DSM 5456 / JCM 9403)
          Length = 466

 Score = 66.1 bits (154), Expect = 8e-10
 Identities = 50/177 (28%), Positives = 84/177 (47%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II +IGP+S +  V+ ++ E G++  R+NF+HG      E     REAE+    K G P 
Sbjct: 8   IIASIGPSSGSPEVILRLAELGVSGFRINFAHGEPSLWREWAEYVREAER----KTGRP- 62

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            LA+  D  GP IR G ++      ++L  G+  +     +  E G+   I +  + +  
Sbjct: 63  -LALIGDLVGPSIRLGRVKN----PIKLNAGDRAEFRCVEE-SEGGDTKIIPLPVRRVYE 116

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           V+  G+ I +DDG + +    VS  +          + SRK + + G    LP +S+
Sbjct: 117 VLDEGDLIVMDDGRVRLRVLEVSGYSAIVEALTPATITSRKAIAIRGKDPGLPTLSQ 173


>UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep:
           Pyruvate kinase - Sulfolobus solfataricus
          Length = 452

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 54/173 (31%), Positives = 90/173 (52%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GP+S       K +   ++V R+NF+HG    H    R   +  ++Y+  
Sbjct: 1   MRKTKIVATLGPSSEEKV---KELAEYVDVFRINFAHGDETSH----RKYFDLIRTYA-- 51

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
              P S +I +D  GP++R G L+      +E+KKG+ I       + +K   D I VD 
Sbjct: 52  ---PES-SIIVDLPGPKLRLGELK----EPIEVKKGDKIV------FSQK---DGIPVDD 94

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 678
           +   + VK  + I I DG I +  +S + D +  T+  GG+L SRKG+N+P +
Sbjct: 95  ELFYSAVKENSDILIADGTIRVRVKSKAKDRVEGTVIEGGILLSRKGINIPNV 147


>UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma
           citri|Rep: Pyruvate kinase - Spiroplasma citri
          Length = 192

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 34/73 (46%), Positives = 44/73 (60%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II TIGP++ +   +E++ +TGM   R+NFSHG H      I   RE     SAK+G P 
Sbjct: 15  IITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREV----SAKIGKPI 70

Query: 355 SLAIALDTKGPEI 393
           S  + LDTKGPEI
Sbjct: 71  S--VLLDTKGPEI 81


>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
           n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
           family protein - Tetrahymena thermophila SB210
          Length = 495

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 48/181 (26%), Positives = 82/181 (45%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342
           R + I+CT+GP S +V ++ K++++GMNVAR+ + HG                     K 
Sbjct: 22  RKTKIVCTLGPQSSSVEMICKLLDSGMNVARITYCHG--------------------LKQ 61

Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522
           G     ++  D K  EI+      G   ++   +    K+   P+Y+  G+   I     
Sbjct: 62  GPDIRTSLLKDKKPIEIKK-----GQKLKITFNRFLIQKVDEQPEYE--GDEQGIGCSIA 114

Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
            ++ +V+ G  + + D  I      V+   +    EN G+L   K V LPG+ +DLP +S
Sbjct: 115 -LSKLVQVGQHVLLSDNTIYSHVVEVNESDIVVQFENEGILNEVKNVRLPGVKIDLPTIS 173

Query: 703 E 705
           E
Sbjct: 174 E 174


>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
           whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_171, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 622

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 53/181 (29%), Positives = 89/181 (49%), Gaps = 11/181 (6%)
 Frame = +1

Query: 163 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           R + I+ T+G   + N  ++  ++++G  + R+N +HG+    +E IR  R +    S  
Sbjct: 258 RTAHIMVTVGQEVTENETLITDILKSGATIIRINCAHGNPSIWSEIIRRVRRS----SQM 313

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGET--IKLTTSPDYQE--KGNADTI 507
           L  P    I +D  GP++RTG ++ G    V L+ G+   I L +S +  E  +   D  
Sbjct: 314 LEKP--CRILMDLAGPKLRTGNMKAG-PCFVRLRVGDLLIISLDSSIEQDELTQPTVDAY 370

Query: 508 YVDYKN--ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 669
            V   +  + + VKPG  I  DDG I  + Q  SA  +  +I +    G  LG+ K +N+
Sbjct: 371 RVTCPSSFLFDSVKPGEPIAFDDGKIWGVIQGTSASEIIVSITHASPRGTKLGAEKSINI 430

Query: 670 P 672
           P
Sbjct: 431 P 431


>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
           Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
          Length = 548

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 41/163 (25%), Positives = 81/163 (49%), Gaps = 1/163 (0%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + ++CT+GPA   V  L  +   GM VAR+N  HG   +H   +R  R   +     
Sbjct: 62  LRKTKLVCTVGPAC--VGALPALARGGMGVARVNLCHGGRGWHRAVMREVRRLNEE---- 115

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
               F +++ +DT+G ++   + + GG+A V+ + G     T+     ++ +  T++V++
Sbjct: 116 --EGFCVSLMVDTEGSQLL--VADHGGAASVKAEDGSEWLFTSK--RTDESHPFTMHVNF 169

Query: 520 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 645
              +  +  G+ + ID G+ +  + + V  D L C   + G+L
Sbjct: 170 DKFSEDILVGDELVIDGGMATFEVIEKVGND-LRCKCTDPGLL 211


>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
           Pyruvate kinase - Nosema bombycis
          Length = 441

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 46/171 (26%), Positives = 85/171 (49%)
 Frame = +1

Query: 166 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 345
           ++ II T+   S +   L   ++ G+++ R+N SHG+   H  +I N R+  K    ++G
Sbjct: 5   MTKIIVTVSSVSDDEETLTNFLKEGVHIFRINLSHGTSYQHEHSILNIRKCAK----EMG 60

Query: 346 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKN 525
                 I LDT+GPE+R  + E    +E+ LK+G+  K+T    +     ++ I++   +
Sbjct: 61  --IVPVICLDTRGPEVRIEIAE---RSEIPLKEGD--KIT----FSNVRTSNKIFLPIPD 109

Query: 526 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 678
            T      ++I++DD +++I     S    T    N   L + K  +LPG+
Sbjct: 110 FTKFPLK-SKIYLDDAMLAIEVLETSKCECTGRAMNSHRLKNNKKASLPGL 159


>UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 659

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 44/149 (29%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
 Frame = +1

Query: 238 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG----L 405
           G+    +N   G+   +   I   REAE S S +LG P + ++ +        TG     
Sbjct: 175 GVRCFMVNLFEGTQHDNQSLIVKLREAEISVSKELGFPVTSSVMVKISPRHQFTGGFSTQ 234

Query: 406 LEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 585
               G   VEL +G+ + LT    Y ++ NAD IYV+ + +   V P + I I +  I +
Sbjct: 235 FRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQL 293

Query: 586 ICQSVSADTLTCTIENGGMLGSRKGVNLP 672
           + +S+ AD L   +  GGML +   V  P
Sbjct: 294 MVRSIHADHLKGCVARGGMLYAHMPVLFP 322


>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
           violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
          Length = 501

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 8/189 (4%)
 Frame = +1

Query: 163 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           R + I+ T+   A  +  +L  ++  GMN AR+N  H S       + N R AE+     
Sbjct: 142 RATRIMVTLPSEAEGDYRLLCALIRAGMNCARINCVHDSETVWERMVGNIRRAEREVGR- 200

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADT---IY 510
                +  I +D  GP++RTG L    +  + L+KGE + L    +       D+   + 
Sbjct: 201 -----ACRILMDLGGPKLRTGPL----AEPLTLRKGEGLVLCRDAEEGRSACEDSPARVV 251

Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGI 678
                I   V+ G  +  DDG I  + + V+ D +   I    + G  L + KG+N P  
Sbjct: 252 CAVSGIYGGVQVGEAVLFDDGKIESVVRGVAQDEIQLEITRADDKGSRLAADKGINFPES 311

Query: 679 PVDLPAVSE 705
            + L  +SE
Sbjct: 312 RLKLRGLSE 320


>UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 461

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 27/35 (77%), Positives = 28/35 (80%)
 Frame = +1

Query: 601 SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           SAD L C I NGGMLGSRKGVNLP   VDLPA+SE
Sbjct: 117 SADYLDCKIINGGMLGSRKGVNLPNAEVDLPALSE 151


>UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter
           sphaeroides|Rep: Pyruvate kinase - Rhodobacter
           sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 /
           DSM158)
          Length = 508

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 44/174 (25%), Positives = 82/174 (47%), Gaps = 4/174 (2%)
 Frame = +1

Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375
           A+ + A++ +++  G +  R+N +H   E  A  I + R++E+    KL       I++D
Sbjct: 161 AASDPAIVRELVAAGADAFRINCAHDGPEAWAAMIGHIRKSERMTGRKL------PISMD 214

Query: 376 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNR 555
             GP+ R  + + GG     L+ G+       P    +G    + + +  +   + PG +
Sbjct: 215 LGGPKFR--VTKTGGPLPKRLQAGDRFAFVEKPSLAPEGRGWAM-LGHPALLAALAPGVQ 271

Query: 556 IFIDDG-LISIICQSVSADTLTCTI---ENGGMLGSRKGVNLPGIPVDLPAVSE 705
           + +DDG L + + Q+     L       E G  L   +GVNLPG  +D+ A++E
Sbjct: 272 VSVDDGKLWATVIQTGRGHALLEVDRVGERGLKLKPGRGVNLPGSHLDVAALTE 325


>UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida
           albicans|Rep: Pyruvate kinase - Candida albicans (Yeast)
          Length = 92

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
 Frame = +1

Query: 463 TTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-SADTLTCTIENGG 639
           TT   Y+ K +   + +DYKNIT V+ PG  I++DDG++S    SV    TL     N G
Sbjct: 12  TTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLSFEVISVDDQQTLKVRSLNAG 71

Query: 640 MLGSRKGVN 666
           M+ S K  N
Sbjct: 72  MISSHKTAN 80


>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
           Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
           Hrk 5)
          Length = 464

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 40/177 (22%), Positives = 76/177 (42%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           ++ T+GP+S +   +++M+  G+N  R+NFSH  +    E  +  R  E           
Sbjct: 6   LVATLGPSSWSEETMKRMVAEGVNAFRLNFSHVDYARFEELAKQVRRLETPLR------- 58

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            L +  D +GP IR G       A  +++ G+ +  T S   +EK     + V       
Sbjct: 59  PLTLIADLQGPVIRLGEF-----APFQVRPGDRVTFTLSSKTEEK---YAVPVPNGVFFE 110

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           +V+ G+ + ++ G ++        +         G +  RK V + G  + LP ++E
Sbjct: 111 IVREGDEVLVEGGRLAFRIVDAGPEKAVGEALLEGEVKPRKTVTVRGKDIPLPTITE 167


>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
           parvum|Rep: Pyruvate kinase - Ureaplasma parvum
           (Ureaplasma urealyticum biotype 1)
          Length = 474

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 45/168 (26%), Positives = 74/168 (44%), Gaps = 5/168 (2%)
 Frame = +1

Query: 217 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 396
           ++ ++ +G+N+ RMN SHG  + H    +  ++       K      + I  DTKGPEIR
Sbjct: 41  IKDLILSGVNIFRMNLSHGDQKIHLFRTQLIKKIADELKIK------VEILFDTKGPEIR 94

Query: 397 TGLLEGGGSAEVELKKGETI---KLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFID 567
              +         +K  E I   K      + E    D       N+ + VK  +RI ID
Sbjct: 95  VCEMSDNNFI---IKNSEVIIHCKEKVLGSFNEFSVTDA--TGQYNMISDVKINHRILID 149

Query: 568 DGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           DG + +I + +    + +  T +N   L + K +NLP     LP +S+
Sbjct: 150 DGKLILIVKKIDFLKNIIYTTAKNSYSLKTNKRLNLPDANYSLPFLSK 197


>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Synechococcus sp. (strain
           JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
           B-Prime)
          Length = 476

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 42/186 (22%), Positives = 83/186 (44%), Gaps = 5/186 (2%)
 Frame = +1

Query: 163 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           R + I+ T+   A+    +L +++E GMNVAR+N +H       + + + R+AE     +
Sbjct: 118 RRARIMVTLPSEAAEQPELLLQLLERGMNVARINCAHDEPSVWEKMVAHLRQAEAQTQRR 177

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
                   I LD  GP+IRTG +      + ++ +G+ I LT          +  +    
Sbjct: 178 ------CKILLDLAGPKIRTGPV-AMPPGKTKVYRGDRILLTAKVPEASADISCQVTCSL 230

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIE----NGGMLGSRKGVNLPGIPVD 687
             +   ++ G  ++IDDG I      +    +   ++     G  L + KG+N P   + 
Sbjct: 231 PEVLAHLQVGATVWIDDGKIGARVVRIEPAGVVLEVDKVAPQGKKLRAEKGLNFPDSQLQ 290

Query: 688 LPAVSE 705
           + ++++
Sbjct: 291 IRSLTD 296


>UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium
           beijerinckii NCIMB 8052|Rep: Pyruvate kinase -
           Clostridium beijerinckii NCIMB 8052
          Length = 340

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 48/174 (27%), Positives = 78/174 (44%), Gaps = 6/174 (3%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           II T+GP  ++ AVL+ ++E+G+N  R NF HGS E   E ++  ++ +           
Sbjct: 3   IIGTVGPNVKDRAVLKGIIESGVNALRFNFIHGSAEEFLEFLKMAKDIKS---------- 52

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQE--KGNADTIYVDYKNI 528
            + + LD  G ++R   + G      ++  GE I       Y E  K + + I V   NI
Sbjct: 53  DIQVMLDLSGTKVR---VSGKFQYIFKVYNGEVIYFCGEDKYSEVVKNSKNKIKVIPLNI 109

Query: 529 TNVV---KPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGI 678
            N +   K   +I I D  ++  I   V       TI  GG++   KG N+  +
Sbjct: 110 KNKILNEKDYKQIGIKDNTMTFDIVDKVDGLIKAITI-RGGVIRKWKGCNIKNL 162


>UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate
           kinase, liver and RBC, partial; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to pyruvate kinase,
           liver and RBC, partial - Ornithorhynchus anatinus
          Length = 339

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 21/31 (67%), Positives = 25/31 (80%)
 Frame = +1

Query: 613 LTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           L   +E+GG LGSRKGVN+PG  +DLPAVSE
Sbjct: 55  LVTEVESGGRLGSRKGVNVPGAVLDLPAVSE 85


>UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2;
           Alphaproteobacteria|Rep: Pyruvate kinase - Stappia
           aggregata IAM 12614
          Length = 512

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 44/165 (26%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
 Frame = +1

Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375
           A+ + A +  ++  GMNVAR+N +H   E   +   + R A     A+L     + I +D
Sbjct: 165 AADDPAFVRDLVRKGMNVARLNCAHDGPEAWEKMAAHVRTA-----AELEGR-DVRILMD 218

Query: 376 TKGPEIRTGLLEGGGSAEVELKKGETIKLTT--SPDYQEKGNADTIYVDYKNITNVVKPG 549
             GP+IRT  +        +L  GE  +L    +PD      A T  V    + N ++ G
Sbjct: 219 IAGPKIRTETVVPQKKTP-KLTIGERFRLVVQETPD-AHSDIAVTASVSLPQMVNRLREG 276

Query: 550 NRIFIDD----GLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 672
           +R+  DD    G++  +    +   +T   ++G  +  +KG+NLP
Sbjct: 277 DRLLYDDSKLEGVVEEVSNGEAVIRVTRAKDSGVKIKPQKGINLP 321


>UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Pyruvate kinase, barrel domain containing protein -
           Tetrahymena thermophila SB210
          Length = 747

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 1/147 (0%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA-EKSYSAK 339
           R + I+ TI     +   L+ M+E G+N   +N ++ + +    T+R  R+A EK +  +
Sbjct: 66  RRTKIVGTISSFYSSYENLKSMVEAGLNSFMVNMAYCTPDLLV-TLRKHRDALEKEFDIQ 124

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           L  P +  +    KG  +R G L      E+ L+KG+  ++  +  ++  GN+    VD 
Sbjct: 125 L--PITCVL----KGTLVRIGTLM---QPEIFLRKGQEYRIVLN--HKVLGNSLYCAVDD 173

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSV 600
           K I   VK GN+I ID G IS+  + +
Sbjct: 174 KEIIRRVKVGNQILIDYGQISMTIKRI 200


>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
           Pyruvate kinase - Mycobacterium sp. (strain JLS)
          Length = 615

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
 Frame = +1

Query: 97  ANVGSQLQHMCGLDIDSKSSYIRLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHG 273
           ANVG +L     +D+   +   R + I+ T+   A+ +  ++  ++  GMNVAR+N +H 
Sbjct: 116 ANVGDELLREHAVDLFGPAPAERATRIMVTLPSSAATDPDLVRDLIARGMNVARINCAHD 175

Query: 274 SHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 417
             E       + R A +S   K        +A+D  GP++RTG +  G
Sbjct: 176 DAEAWTAMAGHVRRAAESTGRK------CLVAMDLAGPKLRTGPIRPG 217



 Score = 41.5 bits (93), Expect = 0.020
 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
 Frame = +1

Query: 436 LKKGETIKLTT--SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD 609
           +++G+ + LT   +P   + G A  I      + +  +PG +I  DDG I     +V  D
Sbjct: 336 VQRGDELTLTRDCAPVPADHGGAPRIGCTLPEVFDHARPGEKIRFDDGRIGGEIVAVERD 395

Query: 610 TLTCTIE----NGGMLGSRKGVNLPGIPVDLPAVSE 705
            L   I+     G  LGS KGVN+P   + + A+++
Sbjct: 396 ALRVRIDRTAPGGSKLGSAKGVNVPDTHLPIAALTD 431


>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
           bacterium HTCC2170|Rep: Pyruvate kinase -
           Flavobacteriales bacterium HTCC2170
          Length = 624

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
 Frame = +1

Query: 163 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           R + I+ T+   A+ ++  + K++  GMN AR+N +H + E   + I N + A K    K
Sbjct: 131 RFTRIMVTLPNTAAEDLGFIRKLLANGMNCARINCAHDTPEDWLKMIDNLKIASKRQRKK 190

Query: 340 LGSPFSLAIALDTKGPEIRTG-LLEG 414
                   IA+D  GP++RTG ++EG
Sbjct: 191 C------KIAMDLSGPKLRTGPMVEG 210



 Score = 33.1 bits (72), Expect = 6.8
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 4/48 (8%)
 Frame = +1

Query: 541 KPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLP 672
           K G  I+ DDG I  I + V+A+ +   I    + G  L + KG+NLP
Sbjct: 377 KKGEPIYFDDGKIEGIIEKVTAEDIVVKITHAKDKGSKLKADKGINLP 424


>UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267,
           whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_267, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 314

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
 Frame = +1

Query: 319 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNA 498
           +K++  +    F +AI +DT+G EI  G L    SA+ E   GE I + +   +      
Sbjct: 184 KKAFLTEQEKGFVVAIMMDTEGSEIHMGELGSAPSAKTE--DGE-IWIFSVQTFDSPRPE 240

Query: 499 DTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 645
            TI ++Y      VK G+ + +D G++   + + +  D + C   + G+L
Sbjct: 241 STININYDGFAEDVKVGDELLVDSGMVRFDVIEKIGPD-VKCRCTDPGLL 289


>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
           Pyruvate kinase - Geobacillus kaustophilus
          Length = 660

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
 Frame = +1

Query: 112 QLQHMCGLDIDSKSSYIRLSGIICTIGPA-SRNVAVLEKMMETGMNVARMNFSHGSHEYH 288
           QL H     +    S +R + I+ T+  A      ++E+++  GM++AR+N ++GS E  
Sbjct: 154 QLLHKRAEAVFGSPSSVRPTRIMVTMDEAWVDEPGLIERLLLYGMDIARINCAYGSPETW 213

Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKK 444
              +   R+AEK    +L       I +D  GP+IR   L    G  ++ +KK
Sbjct: 214 EALVAIIRQAEKQLEQQLQGR-RCRIYMDLPGPKIRVDRLAVNAGPMKLSVKK 265


>UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
           ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
           ATCC BAA-548
          Length = 121

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 39/133 (29%), Positives = 60/133 (45%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           ++ + I+ TI  ++    +L  + + GM+V R+N +H         +   R+        
Sbjct: 1   MKYTKIVATINASTCTEELLRGLYKNGMDVVRLNTAHMEIADMDRIVALVRKVSDK---- 56

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
                 LAI +DTKGP IRT  L+    A + LK G+ + LT     QEK     + V+Y
Sbjct: 57  ------LAIMVDTKGPNIRTCNLD----APLALKIGDKLDLTGETVPQEK----AVQVNY 102

Query: 520 KNITNVVKPGNRI 558
              T  V  G RI
Sbjct: 103 SKFTAEVPVGARI 115


>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
           aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
           aquaeolei (strain ATCC 700491 / DSM 11845 /
           VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
           11845))
          Length = 626

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 21/74 (28%), Positives = 41/74 (55%)
 Frame = +1

Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375
           ++++ +++  +++ GMN  R+N +H   E   E I N + A++ +        S  + +D
Sbjct: 154 SAQDPSIIRDLLKAGMNCMRINCAHDDPETWLEMINNLQTAKEEFGQ------SCQVFMD 207

Query: 376 TKGPEIRTGLLEGG 417
             GP+IRTG +E G
Sbjct: 208 LGGPKIRTGEIEPG 221



 Score = 34.3 bits (75), Expect = 3.0
 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
 Frame = +1

Query: 502 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 669
           TI      + + V PG  ++ DDG I  + + V  D     I++    G  L + KG+NL
Sbjct: 373 TISCTMPEVVSQVHPGESVWFDDGKIGGVIEKVETDRFWVKIQHARPEGSKLRAGKGMNL 432

Query: 670 PGIPVDLPAVS 702
           P   +++ +++
Sbjct: 433 PDSQLNVSSLT 443


>UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 105

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = -3

Query: 704 SETAGRSTGMPGRLTPFRDPSIPPFSMVHVRV-SALTD*QMIEMRPSSMKIRFPGFTTFV 528
           S+ AG+ST +PG+LTP  +  +P       +V S+ T+    +  PSS  +  PG  T V
Sbjct: 43  SDKAGKSTSVPGKLTPLWEEILPALRDSTFKVCSSSTEMTSNDKTPSSTYMILPGAMTLV 102

Query: 527 MFL 519
           MFL
Sbjct: 103 MFL 105


>UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep:
           Pyruvate kinase - Methanococcus jannaschii
          Length = 447

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 52/182 (28%), Positives = 81/182 (44%)
 Frame = +1

Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           +R + I+ T+GP+  N   L+K +   ++  R N SH + +Y  E   N    EK+  AK
Sbjct: 5   MRKTKILVTLGPSLENK--LDKAINL-IDGVRFNMSHATTDY-CEKFLNI--LEKNNIAK 58

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519
           +         +D KG +IR   ++        LK GE  K+    D +   N DTI    
Sbjct: 59  V---------MDLKGIKIRIKEVKLKNKI---LKMGE--KVVIGEDIKLNYNIDTI---- 100

Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699
                  + G+ I I+DG I +       D +   +E GG +    GVNLP   ++LP +
Sbjct: 101 -------EEGHFILINDGKIKLRVVE-KTDKIIAVVEVGGEIKEGMGVNLPDTRIELPII 152

Query: 700 SE 705
            E
Sbjct: 153 DE 154


>UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter
           vinelandii AvOP|Rep: Pyruvate kinase - Azotobacter
           vinelandii AvOP
          Length = 165

 Score = 40.7 bits (91), Expect = 0.034
 Identities = 18/51 (35%), Positives = 29/51 (56%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCRE 315
           R + I+ T+G A+     +E +++ G++V R+NFSHG  E H       RE
Sbjct: 3   RRTKIVATLGSATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARATLVRE 53


>UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
           ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
           ATCC BAA-548
          Length = 357

 Score = 40.3 bits (90), Expect = 0.045
 Identities = 18/52 (34%), Positives = 28/52 (53%)
 Frame = +1

Query: 547 GNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702
           G RI  DDG + ++    S   L C  +  G L + K VN+PG  + +PA++
Sbjct: 2   GARIIFDDGAMELLVLGKSGGLLHCEAKRDGELKNHKSVNVPGAELKMPALT 53


>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
           tenax|Rep: Pyruvate kinase - Thermoproteus tenax
          Length = 446

 Score = 40.3 bits (90), Expect = 0.045
 Identities = 36/167 (21%), Positives = 75/167 (44%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           I+ T+GP++  +  +  ++     V R+N SH S       +   R+ E++      S  
Sbjct: 5   IVATLGPSTDRLPDITALLSKVHGV-RINMSHASPSEVEARVNAVRKYEET------SGR 57

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            +AI  D +GP +RTGL+       +++  G  +    +    EKG+   + V  +    
Sbjct: 58  YIAIIADLRGPSVRTGLMR-----PLQITAGARVSFKLA----EKGDG-FVPVPRREFFE 107

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG 675
           V++ G+ + + DG + +   S +  +      + G++ S K + + G
Sbjct: 108 VIEEGDEVLMLDGKLVLRIISAAQTSAEAESLSSGVISSNKAIVVKG 154


>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
           A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri
           (strain A1501)
          Length = 625

 Score = 39.9 bits (89), Expect = 0.060
 Identities = 24/69 (34%), Positives = 39/69 (56%)
 Frame = +1

Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375
           A+ N  ++E +++ GM+ AR+N +H   +     I + R AEK+    LG      +ALD
Sbjct: 150 AAHNRDLIEALIKEGMDCARINCAHDDPDSWRAMIEHVRAAEKA----LGR--ECKVALD 203

Query: 376 TKGPEIRTG 402
             GP++RTG
Sbjct: 204 LAGPKLRTG 212


>UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
           Pyruvate kinase - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 506

 Score = 39.5 bits (88), Expect = 0.079
 Identities = 42/152 (27%), Positives = 62/152 (40%), Gaps = 3/152 (1%)
 Frame = +1

Query: 226 MMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGL 405
           ++  GMN AR+N +H         I + R A    S   G P    I +D  GP+ R   
Sbjct: 160 LLRKGMNCARVNCAHDDPATWEAMIEHLRAA----SHITGQP--CKILMDLGGPKPRIAD 213

Query: 406 LEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS- 582
           +       V +  G+ ++LTT     E G           I   ++ G R++IDDG    
Sbjct: 214 I---FPETVRVHSGDRLRLTTE-ICPEGGEIPQFTCSLPEIVPQLEVGQRVWIDDGRTGG 269

Query: 583 -IICQSVSADTLTCT-IENGGMLGSRKGVNLP 672
            I+ +      LT T  + G  L   KG+N P
Sbjct: 270 RIVSKDAQGVELTITHCKEGQRLKVAKGLNFP 301


>UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep:
           CG12229-PA - Drosophila melanogaster (Fruit fly)
          Length = 571

 Score = 39.5 bits (88), Expect = 0.079
 Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
 Frame = +1

Query: 214 VLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS-----------YSAKLGSPFSL 360
           V + + ET  +  R    +G++ +H +T+ N  +  K+           +SA+     + 
Sbjct: 78  VAKLVTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTT 137

Query: 361 AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYV-DYKNITNV 537
            +AL+  G   R G L    +  V L +G  + LTT   Y+ KG  + +YV + +     
Sbjct: 138 GLALEINGECCRVGRLRN--NCTVMLARGGVVTLTTDESYRYKGFKEIVYVINLRCYLAS 195

Query: 538 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 672
           V+ G+ + I   +   + +++  + LT  I + G++ S   + LP
Sbjct: 196 VQLGDIVMIGREVRGKVVKTL-REALTVMIIDAGLVASYDFIELP 239


>UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter
           jejuni|Rep: Pyruvate kinase - Campylobacter jejuni
          Length = 319

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 40/177 (22%), Positives = 78/177 (44%)
 Frame = +1

Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354
           +I T GP+      L ++ +    + R+N +HG  E    TI N R+ +           
Sbjct: 4   LILTTGPSLGGKINLNQIHQDKF-IYRINGAHGDIESIKNTIINLRKQKAD--------- 53

Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
            + I +D  G +IRT     G S  ++++K +   L                 +YK    
Sbjct: 54  -IDILIDLPGNKIRTS----GISEAIQVEKDKDFSLKIDQ------------FNYKEFYK 96

Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           +VKPG  ++ +D +   I + V+   +  T ++ G+L + KG+++  +  ++P + E
Sbjct: 97  LVKPGMEVYANDSVFLFIVKEVNDKEIIFTSKSTGLLLNNKGMHVRNLHDNIPFLFE 153


>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
           thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 710

 Score = 37.1 bits (82), Expect = 0.42
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
 Frame = +1

Query: 163 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339
           R + I+ TIG  A+ +   +  +++ G +V R+N +HG      E I+  R      S  
Sbjct: 234 RSTHIMVTIGEEATLSETFITDILKAGTSVIRINCAHGDPSIWGEIIKRVRRT----SQM 289

Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGG 417
           L  P    + +D  GP++RTG L+ G
Sbjct: 290 LEMP--CRVHMDLAGPKLRTGTLKPG 313


>UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_00239360;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00239360 - Tetrahymena thermophila SB210
          Length = 1220

 Score = 36.7 bits (81), Expect = 0.55
 Identities = 19/66 (28%), Positives = 34/66 (51%)
 Frame = +1

Query: 325  SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADT 504
            S S +  + F+    LDT GP     +     +  ++++K E+IK+ +   YQ KGN+  
Sbjct: 924  SKSQQNSNQFNQGNQLDTLGPFENNAVQNSLENISLKIEKNESIKIQSKDIYQNKGNSQF 983

Query: 505  IYVDYK 522
            + +D K
Sbjct: 984  LNIDQK 989


>UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium
           perfringens|Rep: Pyruvate kinase - Clostridium
           perfringens
          Length = 364

 Score = 35.9 bits (79), Expect = 0.97
 Identities = 39/167 (23%), Positives = 69/167 (41%), Gaps = 4/167 (2%)
 Frame = +1

Query: 217 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 396
           ++ +++ G N+ RMN SHG H          R+ E        +  ++ I LD +G +IR
Sbjct: 30  IDNIVKGGGNIIRMNLSHGKH----------RDVECCIDYIRSNHKNVKILLDLQGNKIR 79

Query: 397 TGLLEGGGSAEVELKKGETIKLTTSPDYQE-KGNADTIYVDYKNITNVVKPGN---RIFI 564
              +        ++  G+ +   +   Y     N D   +   NI N     N   +I++
Sbjct: 80  ---VANNIYGTFKVNSGDLVYFCSEETYDAYLKNIDRNKLIPLNIKNKFIYNNTFKKIYM 136

Query: 565 DDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
            D  +  I  S +   +   ++ GG++   KG NLP +      VSE
Sbjct: 137 KDATMEFIVISNNNGLIKTKVKLGGVVRKEKGCNLPNLDRKNWGVSE 183


>UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium
           cellulolyticum H10|Rep: S-layer-like region -
           Clostridium cellulolyticum H10
          Length = 1382

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
 Frame = +1

Query: 364 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY-VDYKNI--TN 534
           I ++    ++R  +L+G    E+E+ KGE I +T S    E    D I  V   NI  T 
Sbjct: 243 IKIEKNNNKLRIVILDGNTVKEIEIAKGEEIIVTGSVGTLEIATPDVIVKVIAANISDTK 302

Query: 535 VVKPGNRIFID-DGLISIICQSVSADTLTCTIENGGMLGS 651
           VV     IF+D +  I  +  + SA+      E G ++ +
Sbjct: 303 VVSANASIFVDKESKIKSVSINNSAENTAIKAEKGAVVNT 342


>UniRef50_UPI0000DB7164 Cluster: PREDICTED: similar to CG31559-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to
           CG31559-PA - Apis mellifera
          Length = 739

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
 Frame = +1

Query: 466 TSPDYQEKGNADTIYV--DYKNIT-NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENG 636
           T P   +K N+ T+ +  D  N T ++   G  +  DD   +I C S++   LT  I NG
Sbjct: 293 TPPPLPKKKNSSTVILASDQHNRTGSLTSSGAEVDSDDNESNISCDSLNGGELTDRIANG 352

Query: 637 GMLGSRKG 660
           G+ G+  G
Sbjct: 353 GINGNEAG 360


>UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep:
           Pyruvate kinase - Corynebacterium efficiens
          Length = 630

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 12/107 (11%)
 Frame = +1

Query: 421 SAEVELKKGETIKLTTSPDYQEK----GNADTIYVDYKNITNVVKPGNRIFIDDGLISII 588
           S  + LK G  + LT+     +     G    I          +K G+R+  DDG I+ +
Sbjct: 331 SQRINLKVGNRLFLTSEEVVYDPSAGHGRIPKISCTLPEAVGAIKVGHRVLFDDGSIAAV 390

Query: 589 C--------QSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705
           C          V    +T     G  L + KG+NLP   + LP+++E
Sbjct: 391 CIDRREHDGHHVVELEVTRARPQGVNLAAYKGINLPDSELPLPSLTE 437


>UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor,
           serine/threonine protein kinase; n=1; Methanocorpusculum
           labreanum Z|Rep: Putative anti-sigma regulatory factor,
           serine/threonine protein kinase - Methanocorpusculum
           labreanum (strain ATCC 43576 / DSM 4855 / Z)
          Length = 777

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 17/48 (35%), Positives = 25/48 (52%)
 Frame = +1

Query: 130 GLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 273
           G  ID K +YI+ SG+IC  G A   + V +KM   G  +    ++ G
Sbjct: 349 GTGIDVKGTYIQNSGMICGTGMAGDGICVAKKMTVYGGKIEATGYTTG 396


>UniRef50_A3CQV6 Cluster: Conserved uncharacterized protein; n=9;
           Streptococcus|Rep: Conserved uncharacterized protein -
           Streptococcus sanguinis (strain SK36)
          Length = 133

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
 Frame = +1

Query: 337 KLGSPFSLAIALDTKG-PEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYV 513
           K+ S  +LA AL   G    +T   +G  SA+  +KK   I ++ +PD QEK        
Sbjct: 3   KIFSLLTLAFALLLVGCGSSQTNTDKGSSSADSSVKKELKISISIAPDGQEKSEKTVAVE 62

Query: 514 DYKNITNVVKPGNRIFIDDGLISII 588
           + K   + +K   ++   DG I+ I
Sbjct: 63  EGKTAMDALKKAYKVEEKDGFITSI 87


>UniRef50_Q89VQ2 Cluster: ABC transporter peptide-binding protein;
           n=1; Bradyrhizobium japonicum|Rep: ABC transporter
           peptide-binding protein - Bradyrhizobium japonicum
          Length = 532

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 20/63 (31%), Positives = 30/63 (47%)
 Frame = +1

Query: 304 NCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQ 483
           N +  + S  A L S ++          ++RT  +  G    VE K  E+IKLT +PDY 
Sbjct: 159 NLKRPQPSLLALLASGYTPVYPCHVSPGDMRTHPIGTGPFKFVEFKANESIKLTRNPDYW 218

Query: 484 EKG 492
            +G
Sbjct: 219 REG 221


>UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding
           subunit ClpA; n=1; Shewanella baltica OS223|Rep:
           ATP-dependent Clp protease, ATP-binding subunit ClpA -
           Shewanella baltica OS223
          Length = 66

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 4/51 (7%)
 Frame = +1

Query: 316 AEKSYSAKLGS-PFSLAIALDTKGP---EIRTGLLEGGGSAEVELKKGETI 456
           AEK Y   +G+ P +  +    K P   EI  G+LE GG A V++K+GE +
Sbjct: 3   AEKGYDKNMGARPMARVVTELIKRPLADEILFGVLESGGVAHVDVKEGELV 53


>UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3;
           Trypanosoma|Rep: Putative uncharacterized protein -
           Trypanosoma cruzi
          Length = 435

 Score = 34.3 bits (75), Expect = 3.0
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
 Frame = +1

Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA--EKSYSA 336
           R+SG++ T+ P   + A+ E  +     +A +  +H   E HA+    C  A  E+  S+
Sbjct: 30  RVSGLLFTVNPRQESKALRELQLYLHPLIADLEEAHKRVEEHADARGRCDNATTEEQSSS 89

Query: 337 KLGSPFSLAIALDTK---GPEIRTGLLEGGGSAEVELKK--GETIKLTTSPDYQEKGNAD 501
           K+ +     IA  T      E+   +   GG    E+++   +  K   S D  EK + D
Sbjct: 90  KMSTDAGGKIAPSTSSLLAAELAEYITTRGGQRRHEMRRIPMKEEKSDVSDDEDEKKSTD 149

Query: 502 TIYVDYKNITNVVKPGNRIFIDDG 573
               +  N +N     NR   D G
Sbjct: 150 NNNNNNNNNSNNNILRNRSSDDGG 173


>UniRef50_A3CLR6 Cluster: Fibril-like structure subunit FibA,
           putative; n=1; Streptococcus sanguinis SK36|Rep:
           Fibril-like structure subunit FibA, putative -
           Streptococcus sanguinis (strain SK36)
          Length = 1273

 Score = 33.5 bits (73), Expect = 5.2
 Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
 Frame = +1

Query: 370 LDTKGPEIRTG--LLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534
           LD K  ++  G   L+ G    +E KKG+T+ +  +P+Y +  ++  I + YK  TN
Sbjct: 372 LDYKELKVEAGGNALQEGRDYTIE-KKGQTVTVKMTPEYVKANSSQDIVITYKTATN 427


>UniRef50_Q58MH8 Cluster: Putative uncharacterized protein; n=1;
           Cyanophage P-SSM2|Rep: Putative uncharacterized protein
           - Cyanophage P-SSM2
          Length = 331

 Score = 33.5 bits (73), Expect = 5.2
 Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +1

Query: 370 LDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEK---GNADTIYVDYKNIT--N 534
           LD K P+I TG+++G   A ++L  GET +    P YQ K       T  V+ K I   +
Sbjct: 117 LDDKIPDIMTGIIKGCEIAGMDLLGGETAE---HPQYQMKIDLAGFCTGIVEKKKIIDGS 173

Query: 535 VVKPGNRI 558
           V+KP +RI
Sbjct: 174 VIKPSDRI 181


>UniRef50_Q8EYH8 Cluster: MutS-like mismatch repair protein,
           ATPases; n=4; Leptospira|Rep: MutS-like mismatch repair
           protein, ATPases - Leptospira interrogans
          Length = 610

 Score = 33.1 bits (72), Expect = 6.8
 Identities = 49/171 (28%), Positives = 73/171 (42%), Gaps = 22/171 (12%)
 Frame = +1

Query: 130 GLDIDSKSSYIRLSGIICTIG------PASR-NVAVLEKMMETGMNVARMNFSHGSHEYH 288
           G ++  K++Y+R  G+   +       PAS+ ++ VL+  + T M     N   G   ++
Sbjct: 441 GSNMSGKTTYLRTIGVASILSMAGGPVPASKFSLPVLK--IHTSMR-NEDNLEEGISFFY 497

Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468
           AE +R   E  K    K  S   L   +  KG   R   L   G  + ELKK  TI   T
Sbjct: 498 AE-VRRLSEIVKKIRDKNSSHLVLLDEI-LKGTNTRERSLACKGILK-ELKKNRTIVFVT 554

Query: 469 SPD-------------YQEKGNADTIYVDYKNITNVVKPGN--RIFIDDGL 576
           S D             +QE+    T+Y DYK    +V+  N  RI + +GL
Sbjct: 555 SHDLELAKVEGVILKHFQEEVLDGTMYFDYKIREGLVETSNALRILVQEGL 605


>UniRef50_Q2AHN9 Cluster: Radical SAM; n=1; Halothermothrix orenii H
           168|Rep: Radical SAM - Halothermothrix orenii H 168
          Length = 231

 Score = 33.1 bits (72), Expect = 6.8
 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
 Frame = +1

Query: 364 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY---VDYKNITN 534
           IA+D K P  R GLL G      ++K+   I L ++ DY+ +      Y    D   I  
Sbjct: 120 IAMDIKAPFSRYGLLAGSSKYNNQIKESINILLNSNIDYEFRTTVIPGYHTENDLIKIAE 179

Query: 535 VVKPGNRIFIDD 570
           ++K   R FI +
Sbjct: 180 LIKGAGRYFIQN 191


>UniRef50_Q3EBL2 Cluster: Uncharacterized protein At2g37440.1; n=3;
           Arabidopsis thaliana|Rep: Uncharacterized protein
           At2g37440.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 479

 Score = 33.1 bits (72), Expect = 6.8
 Identities = 18/40 (45%), Positives = 22/40 (55%)
 Frame = -2

Query: 639 TSVFNGTRKSVSADRLTDDRDEAIVDEDSVSWLHDIRYVL 520
           T +F  TR S S+    D R E I+D D V WL D+ Y L
Sbjct: 276 TEIFKRTRFSRSSK---DSRPETIMDHDKVIWLGDLNYRL 312


>UniRef50_Q46513 Cluster: ORF 2 gene product; n=1; Desulfurococcus
           mobilis|Rep: ORF 2 gene product - Desulfurococcus
           mobilis
          Length = 87

 Score = 32.7 bits (71), Expect = 9.0
 Identities = 23/87 (26%), Positives = 44/87 (50%)
 Frame = +1

Query: 226 MMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGL 405
           M+  G    R+N +HG      E ++  RE     S++L    ++ + LDT GP++R+G 
Sbjct: 1   MVREGAAGFRINCAHGDEADWLEYVKIVREV----SSELDQ--AIPLILDTPGPQVRSGD 54

Query: 406 LEGGGSAEVELKKGETIKLTTSPDYQE 486
            +     E ++ +G+ +  +  PD +E
Sbjct: 55  FQ-----EFKVVRGDKVLFSMDPDAKE 76


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.135    0.390 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 715,959,678
Number of Sequences: 1657284
Number of extensions: 14737923
Number of successful extensions: 51288
Number of sequences better than 10.0: 175
Number of HSP's better than 10.0 without gapping: 48868
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51042
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 56198352344
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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