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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS20127
         (726 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.    54   7e-07
DQ266047-1|ABB70405.1|  570|Homo sapiens ADAMTS16s alternative s...    48   3e-05
AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disinte...    48   3e-05
AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.     48   3e-05
AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptida...    47   6e-05
AB209515-1|BAD92752.1|  847|Homo sapiens a disintegrin-like and ...    47   6e-05
BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.      47   8e-05
BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.      47   8e-05
AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.        47   8e-05
BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase w...    45   3e-04
AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease disinte...    45   3e-04
AF170084-1|AAF15317.1|  967|Homo sapiens metalloproteinase with ...    44   4e-04
BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase w...    44   7e-04
AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.     44   7e-04
AF141293-1|AAF02493.1|  518|Homo sapiens ADAMTS5 protein protein.      43   0.001
BC093777-1|AAH93777.1|  930|Homo sapiens ADAM metallopeptidase w...    43   0.001
BC093775-1|AAH93775.1|  930|Homo sapiens ADAM metallopeptidase w...    43   0.001
AP001697-2|BAA95503.1|  517|Homo sapiens disintegrin-like and me...    43   0.001
AF142099-1|AAD49577.1|  930|Homo sapiens aggrecanase-2 protein.        43   0.001
BC036515-1|AAH36515.1|  967|Homo sapiens ADAM metallopeptidase w...    41   0.004
AP001697-1|BAA95502.1|  967|Homo sapiens metalloprotease with th...    41   0.004
AL162080-1|CAB82413.1|  550|Homo sapiens hypothetical protein pr...    41   0.004
AF207664-1|AAF23772.1|  967|Homo sapiens matrix metalloprotease ...    41   0.004
AF060152-1|AAD48080.1|  950|Homo sapiens METH1 protein protein.        41   0.004
AB037767-1|BAA92584.1|  999|Homo sapiens KIAA1346 protein protein.     41   0.004
BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase w...    41   0.005
AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.              41   0.005
AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.        41   0.005
AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase w...    41   0.005
AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.        41   0.005
AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.     41   0.005
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w...    37   0.064
AK131344-1|BAD18500.1|  502|Homo sapiens protein ( Homo sapiens ...    37   0.064
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte...    37   0.064
AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase w...    36   0.15 
AL158826-22|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase ...    36   0.15 
AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.    36   0.15 
DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase w...    36   0.20 
BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.      36   0.20 
BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase w...    36   0.20 
AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand factor-c...    36   0.20 
AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase ...    36   0.20 
AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase ...    36   0.20 
AL358817-5|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase w...    36   0.20 
AL358817-4|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase w...    36   0.20 
AL355344-5|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase w...    36   0.20 
AL355344-4|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase w...    36   0.20 
AL158826-24|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase ...    36   0.20 
AL158826-23|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase ...    36   0.20 
AJ420811-1|CAD12730.1|  344|Homo sapiens ADAMTS-13 protein, trun...    36   0.20 
AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, vari...    36   0.20 
AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disinte...    36   0.20 
AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.             36   0.20 
AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.             36   0.20 
AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and ...    36   0.20 
AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand factor-c...    36   0.20 
AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.             36   0.20 
AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.            35   0.26 
AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-protein...    33   1.0  
X05232-1|CAA28859.1|  477|Homo sapiens preprostromelysin protein.      32   2.4  
U78045-2|AAB36942.1|  477|Homo sapiens stromelysin protein.            32   2.4  
U31799-1|AAB00386.1|  661|Homo sapiens melanocyte protein Pmel 1...    32   2.4  
U20093-1|AAB19181.1|  661|Homo sapiens Pmel 17 protein.                32   2.4  
U01874-1|AAA18479.1|  662|Homo sapiens me20m protein.                  32   2.4  
S73003-1|AAC60634.1|  661|Homo sapiens gp100 protein.                  32   2.4  
M77348-1|AAA60121.1|  668|Homo sapiens Pmel 17 protein protein.        32   2.4  
M32295-1|AAA35930.1|  675|Homo sapiens protein ( Human 95 kD mel...    32   2.4  
J03209-1|AAA36321.1|  477|Homo sapiens matrix metalloproteinase-...    32   2.4  
BT007202-1|AAP35866.1|  661|Homo sapiens silver homolog (mouse) ...    32   2.4  
BC107491-1|AAI07492.1|  477|Homo sapiens matrix metalloproteinas...    32   2.4  
BC107490-1|AAI07491.1|  477|Homo sapiens matrix metallopeptidase...    32   2.4  
BC105954-1|AAI05955.1|  477|Homo sapiens matrix metalloproteinas...    32   2.4  
BC074869-1|AAH74869.1|  477|Homo sapiens matrix metallopeptidase...    32   2.4  
BC074815-1|AAH74815.1|  477|Homo sapiens matrix metalloproteinas...    32   2.4  
BC069716-1|AAH69716.1|  477|Homo sapiens matrix metallopeptidase...    32   2.4  
BC069676-1|AAH69676.1|  477|Homo sapiens matrix metallopeptidase...    32   2.4  
BC001414-1|AAH01414.1|  661|Homo sapiens silver homolog (mouse) ...    32   2.4  
AK223291-1|BAD97011.1|  477|Homo sapiens matrix metalloproteinas...    32   2.4  
AK223283-1|BAD97003.1|  477|Homo sapiens matrix metalloproteinas...    32   2.4  
AF405705-1|AAK95247.1|  477|Homo sapiens matrix metalloproteinas...    32   2.4  
X07820-1|CAA30679.1|  476|Homo sapiens protein ( Human mRNA for ...    31   3.2  
BT007442-1|AAP36110.1|  476|Homo sapiens matrix metalloproteinas...    31   3.2  
BC002591-1|AAH02591.1|  476|Homo sapiens matrix metallopeptidase...    31   3.2  
AY744675-1|AAU21039.1|  476|Homo sapiens matrix metalloproteinas...    31   3.2  
AY358752-1|AAQ89112.1|  513|Homo sapiens MMP27 protein.                31   3.2  
AK222601-1|BAD96321.1|  476|Homo sapiens matrix metalloproteinas...    31   3.2  
AF195192-1|AAG28453.1|  513|Homo sapiens matrix metalloprotease ...    31   3.2  
Y12779-1|CAA73317.1|  483|Homo sapiens enamelysin protein.             31   4.2  
AY692425-1|AAW47398.1|  468|Homo sapiens ADAMTS6 variant 3 protein.    31   4.2  
AY673603-1|AAT70722.1|  483|Homo sapiens matrix metalloproteinas...    31   4.2  
BC028372-1|AAH28372.1|  790|Homo sapiens ADAM metallopeptidase d...    30   7.3  
AY358734-1|AAQ89096.1|  790|Homo sapiens ADAM30 protein.               30   7.3  
AL359752-8|CAI18978.1|  790|Homo sapiens ADAM metallopeptidase d...    30   7.3  
AF171932-1|AAF03780.1|  790|Homo sapiens metallaproteinase-disin...    30   7.3  
AF062282-1|AAC18319.1|  139|Homo sapiens immunoglobulin heavy ch...    30   7.3  
AK223166-1|BAD96886.1|  532|Homo sapiens flavin containing monoo...    30   9.7  

>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
          Length = 1117

 Score = 53.6 bits (123), Expect = 7e-07
 Identities = 35/83 (42%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSL-PRVLPGRLLTLDAQCRKDRG-TSACFKDERVCAQLFCFD 445
           FL+    TCL N P + D L P V PG++   D QCR   G TS   K   VC +L+C  
Sbjct: 455 FLDSGRGTCLDNEPPKRDFLYPAVAPGQVYDADEQCRFQYGATSRQCKYGEVCRELWCLS 514

Query: 446 AGSGYCVAYR-PAAEGSPCGDGS 511
             S  CV    PAAEG+ C  G+
Sbjct: 515 K-SNRCVTNSIPAAEGTLCQTGN 536



 Score = 31.1 bits (67), Expect = 4.2
 Identities = 24/81 (29%), Positives = 31/81 (38%)
 Frame = +3

Query: 33  EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212
           E   S +I ED G  S   +A HE+GH  G  HD            A K       + + 
Sbjct: 382 EPERSCSINEDIGLGSAFTIA-HEIGHNFGMNHDGIGNSCGTKGHGAAK------LMAAH 434

Query: 213 LRHTEKGFRWSPCSCRVFTTF 275
           +      F WS CS    T+F
Sbjct: 435 ITANTNPFSWSACSRDYITSF 455


>DQ266047-1|ABB70405.1|  570|Homo sapiens ADAMTS16s alternative
           splice form protein.
          Length = 570

 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 QSFHHFLNGDTATCLYNSPH--EDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDER-- 418
           Q  H FL+   A CL + P   ++   P  LPG L   + QC+   G  A  C  D +  
Sbjct: 477 QYLHKFLSTAQAICLADQPKPVKEYKYPEKLPGELYDANTQCKWQFGEKAKLCMLDFKKD 536

Query: 419 VCAQLFCFDAGSGYCVAYRPAAEGSPCG 502
           +C  L+C   G      + PAAEG+ CG
Sbjct: 537 ICKALWCHRIGRKCETKFMPAAEGTICG 564



 Score = 37.1 bits (82), Expect = 0.064
 Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
 Frame = +3

Query: 36  KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL 215
           K  S  I EDTG        AHE GH  G +HD               C+  +G IMS  
Sbjct: 413 KYRSCTINEDTG-LGLAFTIAHESGHNFGMIHD----------GEGNMCKKSEGNIMSPT 461

Query: 216 RHTEKG-FRWSPCS 254
                G F WSPCS
Sbjct: 462 LAGRNGVFSWSPCS 475


>AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease
           disintegrin 16 with thrombospondin type I motif protein.
          Length = 1072

 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 QSFHHFLNGDTATCLYNSPH--EDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDER-- 418
           Q  H FL+   A CL + P   ++   P  LPG L   + QC+   G  A  C  D +  
Sbjct: 477 QYLHKFLSTAQAICLADQPKPVKEYKYPEKLPGELYDANTQCKWQFGEKAKLCMLDFKKD 536

Query: 419 VCAQLFCFDAGSGYCVAYRPAAEGSPCG 502
           +C  L+C   G      + PAAEG+ CG
Sbjct: 537 ICKALWCHRIGRKCETKFMPAAEGTICG 564



 Score = 37.1 bits (82), Expect = 0.064
 Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
 Frame = +3

Query: 36  KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL 215
           K  S  I EDTG        AHE GH  G +HD               C+  +G IMS  
Sbjct: 413 KYRSCTINEDTG-LGLAFTIAHESGHNFGMIHD----------GEGNMCKKSEGNIMSPT 461

Query: 216 RHTEKG-FRWSPCS 254
                G F WSPCS
Sbjct: 462 LAGRNGVFSWSPCS 475


>AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.
          Length = 1021

 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 QSFHHFLNGDTATCLYNSPH--EDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDER-- 418
           Q  H FL+   A CL + P   ++   P  LPG L   + QC+   G  A  C  D +  
Sbjct: 274 QYLHKFLSTAQAICLADQPKPVKEYKYPEKLPGELYDANTQCKWQFGEKAKLCMLDFKKD 333

Query: 419 VCAQLFCFDAGSGYCVAYRPAAEGSPCG 502
           +C  L+C   G      + PAAEG+ CG
Sbjct: 334 ICKALWCHRIGRKCETKFMPAAEGTICG 361



 Score = 37.1 bits (82), Expect = 0.064
 Identities = 27/74 (36%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
 Frame = +3

Query: 36  KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL 215
           K  S  I EDTG        AHE GH  G +HD               C+  +G IMS  
Sbjct: 210 KYRSCTINEDTG-LGLAFTIAHESGHNFGMIHD----------GEGNMCKKSEGNIMSPT 258

Query: 216 RHTEKG-FRWSPCS 254
                G F WSPCS
Sbjct: 259 LAGRNGVFSWSPCS 272


>AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptidase
           protein.
          Length = 1077

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSL-PRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFCFD 445
           FL+     CL N P   D + P V PG+    D QCR   G  S   K   VC++L+C  
Sbjct: 418 FLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLS 477

Query: 446 AGSGYCVAYRPAAEGSPC 499
             +       PAAEG+ C
Sbjct: 478 KSNRCITNSIPAAEGTLC 495


>AB209515-1|BAD92752.1|  847|Homo sapiens a disintegrin-like and
           metalloprotease (reprolysin type) with thrombospondin ty
           protein.
          Length = 847

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSL-PRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFCFD 445
           FL+     CL N P   D + P V PG+    D QCR   G  S   K   VC++L+C  
Sbjct: 198 FLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLS 257

Query: 446 AGSGYCVAYRPAAEGSPC 499
             +       PAAEG+ C
Sbjct: 258 KSNRCITNSIPAAEGTLC 275


>BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.
          Length = 676

 Score = 46.8 bits (106), Expect = 8e-05
 Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
 Frame = +2

Query: 275 LNGDTATCLYNSPHEDDSLPRVLPGR--LLTLDAQCRKDRGTS--AC--FKDERVCAQLF 436
           L+G    CL ++P     LP  LPGR  L  LD QCR+  G     C     + VCAQL+
Sbjct: 204 LDGGHGDCLLDAPAAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLW 263

Query: 437 CF-DAGSGYCVAYR---PAAEGSPCGDGSTASTAS 529
           C  D     C       P A+G+PCG G   S  S
Sbjct: 264 CHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGS 298



 Score = 30.7 bits (66), Expect = 5.6
 Identities = 21/75 (28%), Positives = 28/75 (37%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+L   HD             +       F+     H 
Sbjct: 133 SCSVIEDEG-LQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFV-----HL 186

Query: 225 EKGFRWSPCSCRVFT 269
            +   WSPCS    T
Sbjct: 187 NQTLPWSPCSAMYLT 201


>BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.
          Length = 918

 Score = 46.8 bits (106), Expect = 8e-05
 Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
 Frame = +2

Query: 275 LNGDTATCLYNSPHEDDSLPRVLPGR--LLTLDAQCRKDRGTS--AC--FKDERVCAQLF 436
           L+G    CL ++P     LP  LPGR  L  LD QCR+  G     C     + VCAQL+
Sbjct: 446 LDGGHGDCLLDAPAAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLW 505

Query: 437 CF-DAGSGYCVAYR---PAAEGSPCGDGSTASTAS 529
           C  D     C       P A+G+PCG G   S  S
Sbjct: 506 CHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGS 540



 Score = 30.7 bits (66), Expect = 5.6
 Identities = 21/75 (28%), Positives = 28/75 (37%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+L   HD             +       F+     H 
Sbjct: 375 SCSVIEDEG-LQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFV-----HL 428

Query: 225 EKGFRWSPCSCRVFT 269
            +   WSPCS    T
Sbjct: 429 NQTLPWSPCSAMYLT 443


>AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.
          Length = 890

 Score = 46.8 bits (106), Expect = 8e-05
 Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
 Frame = +2

Query: 275 LNGDTATCLYNSPHEDDSLPRVLPGR--LLTLDAQCRKDRGTS--AC--FKDERVCAQLF 436
           L+G    CL ++P     LP  LPGR  L  LD QCR+  G     C     + VCAQL+
Sbjct: 418 LDGGHGDCLLDAPGAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLW 477

Query: 437 CF-DAGSGYCVAYR---PAAEGSPCGDGSTASTAS 529
           C  D     C       P A+G+PCG G   S  S
Sbjct: 478 CHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGS 512



 Score = 30.7 bits (66), Expect = 5.6
 Identities = 21/75 (28%), Positives = 28/75 (37%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+L   HD             +       F+     H 
Sbjct: 347 SCSVIEDEG-LQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFV-----HL 400

Query: 225 EKGFRWSPCSCRVFT 269
            +   WSPCS    T
Sbjct: 401 NQTLPWSPCSAMYLT 415


>BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 15 protein.
          Length = 950

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFCFDA 448
           FL+     CL + P +  SLP  LPG   TL  QC    G  S      + C +L+C   
Sbjct: 414 FLDSGHGDCLLDQPSKPISLPEDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGK 473

Query: 449 GSGYCVA---YRPAAEGSPCGDG 508
             G  V    + P A+G+ CG+G
Sbjct: 474 AKGQMVCQTRHFPWADGTSCGEG 496


>AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease
           disintegrin 15 with thrombospondin domains protein.
          Length = 950

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT-SACFKDERVCAQLFCFDA 448
           FL+     CL + P +  SLP  LPG   TL  QC    G  S      + C +L+C   
Sbjct: 414 FLDSGHGDCLLDQPSKPISLPEDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGK 473

Query: 449 GSGYCVA---YRPAAEGSPCGDG 508
             G  V    + P A+G+ CG+G
Sbjct: 474 AKGQMVCQTRHFPWADGTSCGEG 496


>AF170084-1|AAF15317.1|  967|Homo sapiens metalloproteinase with
           thrombospondin type 1 motifs ADAMTS1 protein.
          Length = 967

 Score = 44.4 bits (100), Expect = 4e-04
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + PH    LP  LPG     + QC+   G  +  C      C+ L+C  
Sbjct: 454 FLDNGHGECLMDKPHNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTG 513

Query: 446 AGSGYCVA---YRPAAEGSPCGDG 508
              G  V    + P A+G+ CG+G
Sbjct: 514 TSGGVLVCQTKHFPWADGTSCGEG 537



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 22/77 (28%), Positives = 34/77 (44%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+    HD             +        ++S+L H+
Sbjct: 384 SCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMMAS--MLSNLDHS 440

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WSPCS  + T+F
Sbjct: 441 QP---WSPCSAYMITSF 454


>BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 18 protein.
          Length = 1221

 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
 Frame = +2

Query: 233 FQMVAVQLQSFHHFLNGDTATCLYNSPHEDDSL--PRVLPGRLLTLDAQCRKDRGTSA-- 400
           F   +   Q    FL+   A CL + P +      P  LPG++   D QC+   G  A  
Sbjct: 472 FSWSSCSRQYLKKFLSTPQAGCLVDEPKQAGQYKYPDKLPGQIYDADTQCKWQFGAKAKL 531

Query: 401 CFKD--ERVCAQLFCFDAGSGYCVAYRPAAEGSPCG 502
           C     + +C  L+C   G      + PAAEG+ CG
Sbjct: 532 CSLGFVKDICKSLWCHRVGHRCETKFMPAAEGTVCG 567



 Score = 35.1 bits (77), Expect = 0.26
 Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 1/81 (1%)
 Frame = +3

Query: 36  KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL 215
           K  S  I EDTG        AHE GH  G +HD               CR  +G IMS  
Sbjct: 416 KYRSCTINEDTG-LGLAFTIAHESGHNFGMIHD----------GEGNPCRKAEGNIMSPT 464

Query: 216 RHTEKG-FRWSPCSCRVFTTF 275
                G F WS CS +    F
Sbjct: 465 LTGNNGVFSWSSCSRQYLKKF 485


>AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.
          Length = 1081

 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
 Frame = +2

Query: 233 FQMVAVQLQSFHHFLNGDTATCLYNSPHEDDSL--PRVLPGRLLTLDAQCRKDRGTSA-- 400
           F   +   Q    FL+   A CL + P +      P  LPG++   D QC+   G  A  
Sbjct: 471 FSWSSCSRQYLKKFLSTPQAGCLVDEPKQAGQYKYPDKLPGQIYDADTQCKWQFGAKAKL 530

Query: 401 CFKD--ERVCAQLFCFDAGSGYCVAYRPAAEGSPCG 502
           C     + +C  L+C   G      + PAAEG+ CG
Sbjct: 531 CSLGFVKDICKSLWCHRVGHRCETKFMPAAEGTVCG 566



 Score = 35.1 bits (77), Expect = 0.26
 Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 1/81 (1%)
 Frame = +3

Query: 36  KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDL 215
           K  S  I EDTG        AHE GH  G +HD               CR  +G IMS  
Sbjct: 415 KYRSCTINEDTG-LGLAFTIAHESGHNFGMIHD----------GEGNPCRKAEGNIMSPT 463

Query: 216 RHTEKG-FRWSPCSCRVFTTF 275
                G F WS CS +    F
Sbjct: 464 LTGNNGVFSWSSCSRQYLKKF 484


>AF141293-1|AAF02493.1|  518|Homo sapiens ADAMTS5 protein protein.
          Length = 518

 Score = 43.2 bits (97), Expect = 0.001
 Identities = 29/84 (34%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SACFKDERVCAQLFCFD 445
           FL+     CL + P +    P  LPG+      QC    G   S C   + VCA+L+C  
Sbjct: 51  FLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGXD-VCARLWCAV 109

Query: 446 AGSGYCVAYR---PAAEGSPCGDG 508
              G  V      PA EG+PCG G
Sbjct: 110 VRQGQMVCLTKKLPAVEGTPCGKG 133


>BC093777-1|AAH93777.1|  930|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
          Length = 930

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SACFKDERVCAQLFCFD 445
           FL+     CL + P +    P  LPG+      QC    G   S C     VCA+L+C  
Sbjct: 463 FLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVC-PGMDVCARLWCAV 521

Query: 446 AGSGYCVAYR---PAAEGSPCGDG 508
              G  V      PA EG+PCG G
Sbjct: 522 VRQGQMVCLTKKLPAVEGTPCGKG 545



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 25/77 (32%), Positives = 32/77 (41%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S A+IED G  +   VA HE+GHLLG  HD             +K       + S L   
Sbjct: 393 SCAVIEDDGLHAAFTVA-HEIGHLLGLSHDDSKFCEETFGSTEDK-----RLMSSILTSI 446

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WS C+    T F
Sbjct: 447 DASKPWSKCTSATITEF 463


>BC093775-1|AAH93775.1|  930|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
          Length = 930

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SACFKDERVCAQLFCFD 445
           FL+     CL + P +    P  LPG+      QC    G   S C     VCA+L+C  
Sbjct: 463 FLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVC-PGMDVCARLWCAV 521

Query: 446 AGSGYCVAYR---PAAEGSPCGDG 508
              G  V      PA EG+PCG G
Sbjct: 522 VRQGQMVCLTKKLPAVEGTPCGKG 545



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 25/77 (32%), Positives = 32/77 (41%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S A+IED G  +   VA HE+GHLLG  HD             +K       + S L   
Sbjct: 393 SCAVIEDDGLHAAFTVA-HEIGHLLGLSHDDSKFCEETFGSTEDK-----RLMSSILTSI 446

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WS C+    T F
Sbjct: 447 DASKPWSKCTSATITEF 463


>AP001697-2|BAA95503.1|  517|Homo sapiens disintegrin-like and
           metalloprotease with thrombospondin type 1 motif, 5
           protein.
          Length = 517

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SACFKDERVCAQLFCFD 445
           FL+     CL + P +    P  LPG+      QC    G   S C     VCA+L+C  
Sbjct: 50  FLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVC-PGMDVCARLWCAV 108

Query: 446 AGSGYCVAYR---PAAEGSPCGDG 508
              G  V      PA EG+PCG G
Sbjct: 109 VRQGQMVCLTKKLPAVEGTPCGKG 132


>AF142099-1|AAD49577.1|  930|Homo sapiens aggrecanase-2 protein.
          Length = 930

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGT--SACFKDERVCAQLFCFD 445
           FL+     CL + P +    P  LPG+      QC    G   S C     VCA+L+C  
Sbjct: 463 FLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVC-PGMDVCARLWCAV 521

Query: 446 AGSGYCVAYR---PAAEGSPCGDG 508
              G  V      PA EG+PCG G
Sbjct: 522 VRQGQMVCLTKKLPAVEGTPCGKG 545



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 25/77 (32%), Positives = 32/77 (41%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S A+IED G  +   VA HE+GHLLG  HD             +K       + S L   
Sbjct: 393 SCAVIEDDGLHAAFTVA-HEIGHLLGLSHDDSKFCEETFGSTEDK-----RLMSSILTSI 446

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WS C+    T F
Sbjct: 447 DASKPWSKCTSATITEF 463


>BC036515-1|AAH36515.1|  967|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 1 protein.
          Length = 967

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP  LPG     + QC+   G  +  C      C+ L+C  
Sbjct: 454 FLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTG 513

Query: 446 AGSGYCVA---YRPAAEGSPCGDG 508
              G  V    + P A+G+ CG+G
Sbjct: 514 TSGGVLVCQTKHFPWADGTSCGEG 537



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 22/77 (28%), Positives = 34/77 (44%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+    HD             +        ++S+L H+
Sbjct: 384 SCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMMAS--MLSNLDHS 440

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WSPCS  + T+F
Sbjct: 441 QP---WSPCSAYMITSF 454


>AP001697-1|BAA95502.1|  967|Homo sapiens metalloprotease with
           thrombospondin type 1 motifs protein.
          Length = 967

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP  LPG     + QC+   G  +  C      C+ L+C  
Sbjct: 454 FLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTG 513

Query: 446 AGSGYCVA---YRPAAEGSPCGDG 508
              G  V    + P A+G+ CG+G
Sbjct: 514 TSGGVLVCQTKHFPWADGTSCGEG 537



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 22/77 (28%), Positives = 34/77 (44%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+    HD             +        ++S+L H+
Sbjct: 384 SCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMMAS--MLSNLDHS 440

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WSPCS  + T+F
Sbjct: 441 QP---WSPCSAYMITSF 454


>AL162080-1|CAB82413.1|  550|Homo sapiens hypothetical protein
           protein.
          Length = 550

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP  LPG     + QC+   G  +  C      C+ L+C  
Sbjct: 37  FLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTG 96

Query: 446 AGSGYCVA---YRPAAEGSPCGDG 508
              G  V    + P A+G+ CG+G
Sbjct: 97  TSGGVLVCQTKHFPWADGTSCGEG 120


>AF207664-1|AAF23772.1|  967|Homo sapiens matrix metalloprotease
           protein.
          Length = 967

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP  LPG     + QC+   G  +  C      C+ L+C  
Sbjct: 454 FLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTG 513

Query: 446 AGSGYCVA---YRPAAEGSPCGDG 508
              G  V    + P A+G+ CG+G
Sbjct: 514 TSGGVLVCQTKHFPWADGTSCGEG 537



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 22/77 (28%), Positives = 34/77 (44%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+    HD             +        ++S+L H+
Sbjct: 384 SCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMMAS--MLSNLDHS 440

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WSPCS  + T+F
Sbjct: 441 QP---WSPCSAYMITSF 454


>AF060152-1|AAD48080.1|  950|Homo sapiens METH1 protein protein.
          Length = 950

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP  LPG     + QC+   G  +  C      C+ L+C  
Sbjct: 437 FLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTG 496

Query: 446 AGSGYCVA---YRPAAEGSPCGDG 508
              G  V    + P A+G+ CG+G
Sbjct: 497 TSGGVLVCQTKHFPWADGTSCGEG 520



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 22/77 (28%), Positives = 34/77 (44%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+    HD             +        ++S+L H+
Sbjct: 367 SCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMMAS--MLSNLDHS 423

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WSPCS  + T+F
Sbjct: 424 QP---WSPCSAYMITSF 437


>AB037767-1|BAA92584.1|  999|Homo sapiens KIAA1346 protein protein.
          Length = 999

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP  LPG     + QC+   G  +  C      C+ L+C  
Sbjct: 486 FLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTG 545

Query: 446 AGSGYCVA---YRPAAEGSPCGDG 508
              G  V    + P A+G+ CG+G
Sbjct: 546 TSGGVLVCQTKHFPWADGTSCGEG 569



 Score = 36.3 bits (80), Expect = 0.11
 Identities = 22/77 (28%), Positives = 34/77 (44%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S ++IED G        AHE+GH+    HD             +        ++S+L H+
Sbjct: 416 SCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMMAS--MLSNLDHS 472

Query: 225 EKGFRWSPCSCRVFTTF 275
           +    WSPCS  + T+F
Sbjct: 473 QP---WSPCSAYMITSF 486


>BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP   PG+    D QC+   G  +  C +    CA L+C  
Sbjct: 415 FLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSG 474

Query: 446 AGSGYCVA---YRPAAEGSPCG 502
             +G+ +    + P A+G+PCG
Sbjct: 475 HLNGHAMCQTKHSPWADGTPCG 496



 Score = 39.1 bits (87), Expect = 0.016
 Identities = 25/81 (30%), Positives = 34/81 (41%)
 Frame = +3

Query: 33  EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212
           +   S AI+ED G       AAHE+GH+   +HD            +   R     +M+ 
Sbjct: 340 DPARSCAIVEDDG-LQSAFTAAHELGHVFNVLHDNSKPCISLNGPLSTS-RHVMAPVMA- 396

Query: 213 LRHTEKGFRWSPCSCRVFTTF 275
             H +    WSPCS R  T F
Sbjct: 397 --HVDPEEPWSPCSARFITDF 415


>AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.
          Length = 837

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP   PG+    D QC+   G  +  C +    CA L+C  
Sbjct: 415 FLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSG 474

Query: 446 AGSGYCVA---YRPAAEGSPCG 502
             +G+ +    + P A+G+PCG
Sbjct: 475 HLNGHAMCQTKHSPWADGTPCG 496



 Score = 38.7 bits (86), Expect = 0.021
 Identities = 25/81 (30%), Positives = 34/81 (41%)
 Frame = +3

Query: 33  EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212
           +   S AI+ED G       AAHE+GH+   +HD            +   R     +M+ 
Sbjct: 340 DPARSCAIVEDDG-LQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSTS-RHVMAPVMA- 396

Query: 213 LRHTEKGFRWSPCSCRVFTTF 275
             H +    WSPCS R  T F
Sbjct: 397 --HVDPEEPWSPCSARFITDF 415


>AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.
          Length = 837

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP   PG+    D QC+   G  +  C +    CA L+C  
Sbjct: 415 FLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSG 474

Query: 446 AGSGYCVA---YRPAAEGSPCG 502
             +G+ +    + P A+G+PCG
Sbjct: 475 HLNGHAMCQTKHSPWADGTPCG 496



 Score = 38.7 bits (86), Expect = 0.021
 Identities = 25/81 (30%), Positives = 34/81 (41%)
 Frame = +3

Query: 33  EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212
           +   S AI+ED G       AAHE+GH+   +HD            +   R     +M+ 
Sbjct: 340 DPARSCAIVEDDG-LQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSTS-RHVMAPVMA- 396

Query: 213 LRHTEKGFRWSPCSCRVFTTF 275
             H +    WSPCS R  T F
Sbjct: 397 --HVDPEEPWSPCSARFITDF 415


>AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP   PG+    D QC+   G  +  C +    CA L+C  
Sbjct: 415 FLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSG 474

Query: 446 AGSGYCVA---YRPAAEGSPCG 502
             +G+ +    + P A+G+PCG
Sbjct: 475 HLNGHAMCQTKHSPWADGTPCG 496



 Score = 38.7 bits (86), Expect = 0.021
 Identities = 25/81 (30%), Positives = 34/81 (41%)
 Frame = +3

Query: 33  EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212
           +   S AI+ED G       AAHE+GH+   +HD            +   R     +M+ 
Sbjct: 340 DPARSCAIVEDDG-LQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSTS-RHVMAPVMA- 396

Query: 213 LRHTEKGFRWSPCSCRVFTTF 275
             H +    WSPCS R  T F
Sbjct: 397 --HVDPEEPWSPCSARFITDF 415


>AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.
          Length = 837

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP   PG+    D QC+   G  +  C +    CA L+C  
Sbjct: 415 FLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSG 474

Query: 446 AGSGYCVA---YRPAAEGSPCG 502
             +G+ +    + P A+G+PCG
Sbjct: 475 HLNGHAMCQTKHSPWADGTPCG 496



 Score = 38.7 bits (86), Expect = 0.021
 Identities = 25/81 (30%), Positives = 34/81 (41%)
 Frame = +3

Query: 33  EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212
           +   S AI+ED G       AAHE+GH+   +HD            +   R     +M+ 
Sbjct: 340 DPARSCAIVEDDG-LQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSTS-RHVMAPVMA- 396

Query: 213 LRHTEKGFRWSPCSCRVFTTF 275
             H +    WSPCS R  T F
Sbjct: 397 --HVDPEEPWSPCSARFITDF 415


>AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.
          Length = 849

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
 Frame = +2

Query: 272 FLNGDTATCLYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSA--CFKDERVCAQLFCFD 445
           FL+     CL + P     LP   PG+    D QC+   G  +  C +    CA L+C  
Sbjct: 427 FLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSG 486

Query: 446 AGSGYCVA---YRPAAEGSPCG 502
             +G+ +    + P A+G+PCG
Sbjct: 487 HLNGHAMCQTKHSPWADGTPCG 508



 Score = 38.7 bits (86), Expect = 0.021
 Identities = 25/81 (30%), Positives = 34/81 (41%)
 Frame = +3

Query: 33  EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212
           +   S AI+ED G       AAHE+GH+   +HD            +   R     +M+ 
Sbjct: 352 DPARSCAIVEDDG-LQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSTS-RHVMAPVMA- 408

Query: 213 LRHTEKGFRWSPCSCRVFTTF 275
             H +    WSPCS R  T F
Sbjct: 409 --HVDPEEPWSPCSARFITDF 427


>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif 17 protein.
          Length = 1095

 Score = 37.1 bits (82), Expect = 0.064
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 7/85 (8%)
 Frame = +2

Query: 269 HFLNGDTATCLY-NSPHEDDS--LPRVLPGRLLTLDAQCRKDRGTSACF---KDERVCAQ 430
           +FL    +TCL    P    +  LP  LPG   + + QC+   G +A F    +  +CA 
Sbjct: 438 NFLKSKVSTCLLVTDPRSQHTVRLPHKLPGMHYSANEQCQILFGMNATFCRNMEHLMCAG 497

Query: 431 LFCFDAGSGYC-VAYRPAAEGSPCG 502
           L+C   G   C     P  +G+ CG
Sbjct: 498 LWCLVEGDTSCKTKLDPPLDGTECG 522


>AK131344-1|BAD18500.1|  502|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16363 fis, clone THYMU2031139, weakly  similar
           to Homo sapiens zinc metalloprotease ADAMTS7 (ADAMTS7)
           mRNA. ).
          Length = 502

 Score = 37.1 bits (82), Expect = 0.064
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 7/85 (8%)
 Frame = +2

Query: 269 HFLNGDTATCLY-NSPHEDDS--LPRVLPGRLLTLDAQCRKDRGTSACF---KDERVCAQ 430
           +FL    +TCL    P    +  LP  LPG   + + QC+   G +A F    +  +CA 
Sbjct: 195 NFLKSKVSTCLLVTDPRSQHTVRLPHKLPGMHYSANEQCQILFGMNATFCRNMEHLMCAG 254

Query: 431 LFCFDAGSGYC-VAYRPAAEGSPCG 502
           L+C   G   C     P  +G+ CG
Sbjct: 255 LWCLVEGDTSCKTKLDPPLDGTECG 279


>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease
           disintegrin 17, with thrombospondin domains protein.
          Length = 1095

 Score = 37.1 bits (82), Expect = 0.064
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 7/85 (8%)
 Frame = +2

Query: 269 HFLNGDTATCLY-NSPHEDDS--LPRVLPGRLLTLDAQCRKDRGTSACF---KDERVCAQ 430
           +FL    +TCL    P    +  LP  LPG   + + QC+   G +A F    +  +CA 
Sbjct: 438 NFLKSKVSTCLLVTDPRSQHTVRLPHKLPGMHYSANEQCQILFGMNATFCRNMEHLMCAG 497

Query: 431 LFCFDAGSGYC-VAYRPAAEGSPCG 502
           L+C   G   C     P  +G+ CG
Sbjct: 498 LWCLVEGDTSCKTKLDPPLDGTECG 522


>AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 13 protein.
          Length = 1340

 Score = 35.9 bits (79), Expect = 0.15
 Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 2/100 (2%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCRVFTTF*MGTR--RLAYTTLRMKMTLCRE 338
             G  WSPCS R   +        R+A+    +  T  RE
Sbjct: 257 RAGLAWSPCSRRQLLSLLSANEQCRVAFGPKAVACTFARE 296


>AL158826-22|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1340

 Score = 35.9 bits (79), Expect = 0.15
 Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 2/100 (2%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCRVFTTF*MGTR--RLAYTTLRMKMTLCRE 338
             G  WSPCS R   +        R+A+    +  T  RE
Sbjct: 257 RAGLAWSPCSRRQLLSLLSANEQCRVAFGPKAVACTFARE 296


>AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.
          Length = 1340

 Score = 35.9 bits (79), Expect = 0.15
 Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 2/100 (2%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCRVFTTF*MGTR--RLAYTTLRMKMTLCRE 338
             G  WSPCS R   +        R+A+    +  T  RE
Sbjct: 257 RAGLAWSPCSRRQLLSLLSANEQCRVAFGPKAVACTFARE 296


>DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.
          Length = 1205

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +2

Query: 296 CLYNSPHEDD--SLPRVLPGRLLTLDAQCRKDRGTS----ACFKDERVCAQLFCFDAGSG 457
           CL + P + D   LP  LPG   ++D QCR D G        F+    C QL+C    + 
Sbjct: 455 CLLDDPFDHDWPKLPE-LPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNP 513

Query: 458 Y-CVAYR-PAAEGSPCGDG 508
           Y C   + P  +G+ C  G
Sbjct: 514 YFCKTKKGPPLDGTECAAG 532



 Score = 33.1 bits (72), Expect = 1.0
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 389 GFSSAFVVAHETGHVLGMEHD 409


>BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 3 protein.
          Length = 1205

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +2

Query: 296 CLYNSPHEDD--SLPRVLPGRLLTLDAQCRKDRGTS----ACFKDERVCAQLFCFDAGSG 457
           CL + P + D   LP  LPG   ++D QCR D G        F+    C QL+C    + 
Sbjct: 455 CLLDDPFDHDWPKLPE-LPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNP 513

Query: 458 Y-CVAYR-PAAEGSPCGDG 508
           Y C   + P  +G+ C  G
Sbjct: 514 YFCKTKKGPPLDGTECAAG 532



 Score = 33.1 bits (72), Expect = 1.0
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 389 GFSSAFVVAHETGHVLGMEHD 409


>AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand
           factor-cleaving protease precursor protein.
          Length = 1427

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1371

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AL358817-5|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1223

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
 Frame = +2

Query: 296 CLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSGY 460
           CL + P +     P  LPG   ++D QCR D G    T   F+    C QL+C    + Y
Sbjct: 455 CLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPY 514

Query: 461 -CVAYR-PAAEGSPCGDG 508
            C   + P  +G+ C  G
Sbjct: 515 FCKTKKGPPLDGTECAPG 532



 Score = 32.7 bits (71), Expect = 1.4
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 389 GFSSAFVIAHETGHVLGMEHD 409


>AL358817-4|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1226

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
 Frame = +2

Query: 296 CLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSGY 460
           CL + P +     P  LPG   ++D QCR D G    T   F+    C QL+C    + Y
Sbjct: 458 CLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPY 517

Query: 461 -CVAYR-PAAEGSPCGDG 508
            C   + P  +G+ C  G
Sbjct: 518 FCKTKKGPPLDGTECAPG 535



 Score = 32.7 bits (71), Expect = 1.4
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 392 GFSSAFVIAHETGHVLGMEHD 412


>AL355344-5|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1223

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
 Frame = +2

Query: 296 CLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSGY 460
           CL + P +     P  LPG   ++D QCR D G    T   F+    C QL+C    + Y
Sbjct: 455 CLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPY 514

Query: 461 -CVAYR-PAAEGSPCGDG 508
            C   + P  +G+ C  G
Sbjct: 515 FCKTKKGPPLDGTECAPG 532



 Score = 32.7 bits (71), Expect = 1.4
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 389 GFSSAFVIAHETGHVLGMEHD 409


>AL355344-4|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1226

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
 Frame = +2

Query: 296 CLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSGY 460
           CL + P +     P  LPG   ++D QCR D G    T   F+    C QL+C    + Y
Sbjct: 458 CLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPY 517

Query: 461 -CVAYR-PAAEGSPCGDG 508
            C   + P  +G+ C  G
Sbjct: 518 FCKTKKGPPLDGTECAPG 535



 Score = 32.7 bits (71), Expect = 1.4
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 392 GFSSAFVIAHETGHVLGMEHD 412


>AL158826-24|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1371

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AL158826-23|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AJ420811-1|CAD12730.1|  344|Homo sapiens ADAMTS-13 protein,
           truncated variant protein.
          Length = 344

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, variant
           2 protein.
          Length = 1371

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AJ345098-1|CAC87943.1| 1223|Homo sapiens
           metalloprotease-disintegrin protease protein.
          Length = 1223

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
 Frame = +2

Query: 296 CLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSGY 460
           CL + P +     P  LPG   ++D QCR D G    T   F+    C QL+C    + Y
Sbjct: 455 CLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPY 514

Query: 461 -CVAYR-PAAEGSPCGDG 508
            C   + P  +G+ C  G
Sbjct: 515 FCKTKKGPPLDGTECAPG 532



 Score = 32.7 bits (71), Expect = 1.4
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 389 GFSSAFVIAHETGHVLGMEHD 409


>AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.
          Length = 1427

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.
          Length = 1159

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
 Frame = +2

Query: 296 CLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSGY 460
           CL + P +     P  LPG   ++D QCR D G    T   F+    C QL+C    + Y
Sbjct: 391 CLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPY 450

Query: 461 -CVAYR-PAAEGSPCGDG 508
            C   + P  +G+ C  G
Sbjct: 451 FCKTKKGPPLDGTECAPG 468



 Score = 32.7 bits (71), Expect = 1.4
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 325 GFSSAFVIAHETGHVLGMEHD 345


>AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motif 14 prec
           protein.
          Length = 1223

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
 Frame = +2

Query: 296 CLYNSPHEDD-SLPRVLPGRLLTLDAQCRKDRG----TSACFKDERVCAQLFCFDAGSGY 460
           CL + P +     P  LPG   ++D QCR D G    T   F+    C QL+C    + Y
Sbjct: 455 CLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPY 514

Query: 461 -CVAYR-PAAEGSPCGDG 508
            C   + P  +G+ C  G
Sbjct: 515 FCKTKKGPPLDGTECAPG 532



 Score = 32.7 bits (71), Expect = 1.4
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 389 GFSSAFVIAHETGHVLGMEHD 409


>AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand
           factor-cleaving protease protein.
          Length = 1427

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 25/72 (34%), Positives = 29/72 (40%)
 Frame = +3

Query: 45  SVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSDLRHT 224
           S  I EDTG   G+ +A HE+GH  G  HD               C      + SD    
Sbjct: 207 SCLITEDTGFDLGVTIA-HEIGHSFGLEHD---------GAPGSGCGPSGHVMASDGAAP 256

Query: 225 EKGFRWSPCSCR 260
             G  WSPCS R
Sbjct: 257 RAGLAWSPCSRR 268


>AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.
          Length = 1201

 Score = 35.5 bits (78), Expect = 0.20
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +2

Query: 296 CLYNSPHEDD--SLPRVLPGRLLTLDAQCRKDRGTS----ACFKDERVCAQLFCFDAGSG 457
           CL + P + D   LP  LPG   ++D QCR D G        F+    C QL+C    + 
Sbjct: 451 CLLDDPFDHDWPKLPE-LPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNP 509

Query: 458 Y-CVAYR-PAAEGSPCGDG 508
           Y C   + P  +G+ C  G
Sbjct: 510 YFCKTKKGPPLDGTECAAG 528



 Score = 33.1 bits (72), Expect = 1.0
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 385 GFSSAFVVAHETGHVLGMEHD 405


>AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.
          Length = 1207

 Score = 35.1 bits (77), Expect = 0.26
 Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 QSFHHFLNGDTATCLYNS-PHEDDSL--PRVLPGRLLTLDAQCRKDRGTSACFKDER--- 418
           +    FL    + CL  + P   +S+  P  LPG   T D QC+   G  A F  E    
Sbjct: 527 EDLERFLRSKASNCLLQTNPQSVNSVMVPSKLPGMTYTADEQCQILFGPLASFCQEMQHV 586

Query: 419 VCAQLFCFDAGSGYC-VAYRPAAEGSPCGDG 508
           +C  L+C   G   C     P  +G+ C  G
Sbjct: 587 ICTGLWCKVEGEKECRTKLDPPMDGTDCDLG 617


>AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-proteinase
           protein.
          Length = 1211

 Score = 33.1 bits (72), Expect = 1.0
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 72  GFSGIIVAAHEVGHLLGAVHD 134
           GFS   V AHE GH+LG  HD
Sbjct: 399 GFSSAFVVAHETGHVLGMEHD 419


>X05232-1|CAA28859.1|  477|Homo sapiens preprostromelysin protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>U78045-2|AAB36942.1|  477|Homo sapiens stromelysin protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>U31799-1|AAB00386.1|  661|Homo sapiens melanocyte protein Pmel 17
           protein.
          Length = 661

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -3

Query: 127 TAPNKCPTS*AATMIPEKPPVSSMMATEL 41
           TAP + PT+ +  M PEK PVS +M T L
Sbjct: 361 TAPVQMPTAESTGMTPEKVPVSEVMGTTL 389


>U20093-1|AAB19181.1|  661|Homo sapiens Pmel 17 protein.
          Length = 661

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -3

Query: 127 TAPNKCPTS*AATMIPEKPPVSSMMATEL 41
           TAP + PT+ +  M PEK PVS +M T L
Sbjct: 361 TAPVQMPTAESTGMTPEKVPVSEVMGTTL 389


>U01874-1|AAA18479.1|  662|Homo sapiens me20m protein.
          Length = 662

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -3

Query: 127 TAPNKCPTS*AATMIPEKPPVSSMMATEL 41
           TAP + PT+ +  M PEK PVS +M T L
Sbjct: 361 TAPVQMPTAESTGMTPEKVPVSEVMGTTL 389


>S73003-1|AAC60634.1|  661|Homo sapiens gp100 protein.
          Length = 661

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -3

Query: 127 TAPNKCPTS*AATMIPEKPPVSSMMATEL 41
           TAP + PT+ +  M PEK PVS +M T L
Sbjct: 361 TAPVQMPTAESTGMTPEKVPVSEVMGTTL 389


>M77348-1|AAA60121.1|  668|Homo sapiens Pmel 17 protein protein.
          Length = 668

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -3

Query: 127 TAPNKCPTS*AATMIPEKPPVSSMMATEL 41
           TAP + PT+ +  M PEK PVS +M T L
Sbjct: 361 TAPVQMPTAESTGMTPEKVPVSEVMGTTL 389


>M32295-1|AAA35930.1|  675|Homo sapiens protein ( Human 95 kD
           melanocyte-specific secreted glycoprotein mRNA, 3' end.
           ).
          Length = 675

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -3

Query: 127 TAPNKCPTS*AATMIPEKPPVSSMMATEL 41
           TAP + PT+ +  M PEK PVS +M T L
Sbjct: 368 TAPVQMPTAESTGMTPEKVPVSEVMGTTL 396


>J03209-1|AAA36321.1|  477|Homo sapiens matrix metalloproteinase-3
           protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>BT007202-1|AAP35866.1|  661|Homo sapiens silver homolog (mouse)
           protein.
          Length = 661

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -3

Query: 127 TAPNKCPTS*AATMIPEKPPVSSMMATEL 41
           TAP + PT+ +  M PEK PVS +M T L
Sbjct: 361 TAPVQMPTAESTGMTPEKVPVSEVMGTTL 389


>BC107491-1|AAI07492.1|  477|Homo sapiens matrix metalloproteinase
           3, preproprotein protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>BC107490-1|AAI07491.1|  477|Homo sapiens matrix metallopeptidase 3
           (stromelysin 1, progelatinase) protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>BC105954-1|AAI05955.1|  477|Homo sapiens matrix metalloproteinase
           3, preproprotein protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>BC074869-1|AAH74869.1|  477|Homo sapiens matrix metallopeptidase 3
           (stromelysin 1, progelatinase) protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>BC074815-1|AAH74815.1|  477|Homo sapiens matrix metalloproteinase
           3, preproprotein protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>BC069716-1|AAH69716.1|  477|Homo sapiens matrix metallopeptidase 3
           (stromelysin 1, progelatinase) protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>BC069676-1|AAH69676.1|  477|Homo sapiens matrix metallopeptidase 3
           (stromelysin 1, progelatinase) protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>BC001414-1|AAH01414.1|  661|Homo sapiens silver homolog (mouse)
           protein.
          Length = 661

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -3

Query: 127 TAPNKCPTS*AATMIPEKPPVSSMMATEL 41
           TAP + PT+ +  M PEK PVS +M T L
Sbjct: 361 TAPVQMPTAESTGMTPEKVPVSEVMGTTL 389


>AK223291-1|BAD97011.1|  477|Homo sapiens matrix metalloproteinase 3
           preproprotein variant protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>AK223283-1|BAD97003.1|  477|Homo sapiens matrix metalloproteinase 3
           preproprotein variant protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>AF405705-1|AAK95247.1|  477|Homo sapiens matrix metalloproteinase 3
           (stromelysin 1, progelatinase) protein.
          Length = 477

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +DT G +  +VAAHE+GH LG  H
Sbjct: 205 KDTTGTNLFLVAAHEIGHSLGLFH 228


>X07820-1|CAA30679.1|  476|Homo sapiens protein ( Human mRNA for
           metalloproteinase stromelysin-2. ).
          Length = 476

 Score = 31.5 bits (68), Expect = 3.2
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           ED  G +  +VAAHE+GH LG  H
Sbjct: 204 EDASGTNLFLVAAHELGHSLGLFH 227


>BT007442-1|AAP36110.1|  476|Homo sapiens matrix metalloproteinase
           10 (stromelysin 2) protein.
          Length = 476

 Score = 31.5 bits (68), Expect = 3.2
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           ED  G +  +VAAHE+GH LG  H
Sbjct: 204 EDASGTNLFLVAAHELGHSLGLFH 227


>BC002591-1|AAH02591.1|  476|Homo sapiens matrix metallopeptidase 10
           (stromelysin 2) protein.
          Length = 476

 Score = 31.5 bits (68), Expect = 3.2
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           ED  G +  +VAAHE+GH LG  H
Sbjct: 204 EDASGTNLFLVAAHELGHSLGLFH 227


>AY744675-1|AAU21039.1|  476|Homo sapiens matrix metalloproteinase
           10 (stromelysin 2) protein.
          Length = 476

 Score = 31.5 bits (68), Expect = 3.2
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           ED  G +  +VAAHE+GH LG  H
Sbjct: 204 EDASGTNLFLVAAHELGHSLGLFH 227


>AY358752-1|AAQ89112.1|  513|Homo sapiens MMP27 protein.
          Length = 513

 Score = 31.5 bits (68), Expect = 3.2
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +D  GF+  +VAAHE GH LG  H
Sbjct: 203 KDGAGFNLFLVAAHEFGHALGLSH 226


>AK222601-1|BAD96321.1|  476|Homo sapiens matrix metalloproteinase
           10 preproprotein variant protein.
          Length = 476

 Score = 31.5 bits (68), Expect = 3.2
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           ED  G +  +VAAHE+GH LG  H
Sbjct: 204 EDASGTNLFLVAAHELGHSLGLFH 227


>AF195192-1|AAG28453.1|  513|Homo sapiens matrix metalloprotease
           MMP-27 protein.
          Length = 513

 Score = 31.5 bits (68), Expect = 3.2
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 60  EDTGGFSGIIVAAHEVGHLLGAVH 131
           +D  GF+  +VAAHE GH LG  H
Sbjct: 203 KDGAGFNLFLVAAHEFGHALGLSH 226


>Y12779-1|CAA73317.1|  483|Homo sapiens enamelysin protein.
          Length = 483

 Score = 31.1 bits (67), Expect = 4.2
 Identities = 13/22 (59%), Positives = 14/22 (63%)
 Frame = +3

Query: 66  TGGFSGIIVAAHEVGHLLGAVH 131
           T GF+   VAAHE GH LG  H
Sbjct: 215 TNGFNLFTVAAHEFGHALGLAH 236


>AY692425-1|AAW47398.1|  468|Homo sapiens ADAMTS6 variant 3 protein.
          Length = 468

 Score = 31.1 bits (67), Expect = 4.2
 Identities = 24/81 (29%), Positives = 31/81 (38%)
 Frame = +3

Query: 33  EKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDXXXXXXXXXXXXAEKCRWEDGFIMSD 212
           E   S +I ED G  S   +A HE+GH  G  HD            A K       + + 
Sbjct: 382 EPERSCSINEDIGLGSAFTIA-HEIGHNFGMNHDGIGNSCGTKGHEAAK------LMAAH 434

Query: 213 LRHTEKGFRWSPCSCRVFTTF 275
           +      F WS CS    T+F
Sbjct: 435 ITANTNPFSWSACSRDYITSF 455


>AY673603-1|AAT70722.1|  483|Homo sapiens matrix metalloproteinase
           20 (enamelysin) protein.
          Length = 483

 Score = 31.1 bits (67), Expect = 4.2
 Identities = 13/22 (59%), Positives = 14/22 (63%)
 Frame = +3

Query: 66  TGGFSGIIVAAHEVGHLLGAVH 131
           T GF+   VAAHE GH LG  H
Sbjct: 215 TNGFNLFTVAAHEFGHALGLAH 236


>BC028372-1|AAH28372.1|  790|Homo sapiens ADAM metallopeptidase
           domain 30 protein.
          Length = 790

 Score = 30.3 bits (65), Expect = 7.3
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +3

Query: 30  LEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134
           LE   SV+ + DT   +    +AHE+GH +G  HD
Sbjct: 315 LEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHD 349


>AY358734-1|AAQ89096.1|  790|Homo sapiens ADAM30 protein.
          Length = 790

 Score = 30.3 bits (65), Expect = 7.3
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +3

Query: 30  LEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134
           LE   SV+ + DT   +    +AHE+GH +G  HD
Sbjct: 315 LEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHD 349


>AL359752-8|CAI18978.1|  790|Homo sapiens ADAM metallopeptidase
           domain 30 protein.
          Length = 790

 Score = 30.3 bits (65), Expect = 7.3
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +3

Query: 30  LEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134
           LE   SV+ + DT   +    +AHE+GH +G  HD
Sbjct: 315 LEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHD 349


>AF171932-1|AAF03780.1|  790|Homo sapiens
           metallaproteinase-disintegrin protein.
          Length = 790

 Score = 30.3 bits (65), Expect = 7.3
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +3

Query: 30  LEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHD 134
           LE   SV+ + DT   +    +AHE+GH +G  HD
Sbjct: 315 LEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHD 349


>AF062282-1|AAC18319.1|  139|Homo sapiens immunoglobulin heavy chain
           variable region protein.
          Length = 139

 Score = 30.3 bits (65), Expect = 7.3
 Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 7/63 (11%)
 Frame = +3

Query: 324 TLCRECCLVVSLPWTLS--AGRTEAPVRVSRMSECALSC-----SVSTRVAGTAWRTDPP 482
           TLC    L+    W LS    +   P  V       L+C     S+ST   G AW   PP
Sbjct: 3   TLCSTLLLLTIPSWVLSQITLKESGPTLVKPTQTLTLTCTFSGFSISTTAVGVAWFRQPP 62

Query: 483 PRA 491
            +A
Sbjct: 63  GKA 65


>AK223166-1|BAD96886.1|  532|Homo sapiens flavin containing
           monooxygenase 3 isoform 2 variant protein.
          Length = 532

 Score = 29.9 bits (64), Expect = 9.7
 Identities = 16/58 (27%), Positives = 28/58 (48%)
 Frame = +2

Query: 299 LYNSPHEDDSLPRVLPGRLLTLDAQCRKDRGTSACFKDERVCAQLFCFDAGSGYCVAY 472
           L   P  +D LP  +   ++++    ++  GTSA F+D  +   + C    +GY  AY
Sbjct: 278 LRKEPVFNDELPASILCGIVSVKPNVKEFTGTSAIFEDGTIFEGIDCVIFATGYSFAY 335


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,012,268
Number of Sequences: 237096
Number of extensions: 2724995
Number of successful extensions: 8219
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 7281
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8174
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8567175942
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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