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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e96h0036
         (668 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC009771-1|AAH09771.1|  314|Homo sapiens BRCA2 and CDKN1A intera...    64   3e-10
AY064249-1|AAL55440.1|  314|Homo sapiens BRCA2 and Cip1/p21 inte...    64   3e-10
AY064248-1|AAL55439.1|  322|Homo sapiens BRCA2 and Cip1/p21 inte...    64   3e-10
AY064247-2|AAL55438.1|  314|Homo sapiens BRCA2 and Cip1/p21 inte...    64   3e-10
AY064247-1|AAL55436.1|  322|Homo sapiens BRCA2 and Cip1/p21 inte...    64   3e-10
AL360176-8|CAI12093.1|  322|Homo sapiens BRCA2 and CDKN1A intera...    64   3e-10
AL360176-7|CAI12092.1|  292|Homo sapiens BRCA2 and CDKN1A intera...    64   3e-10
AL360176-6|CAI12091.1|  314|Homo sapiens BRCA2 and CDKN1A intera...    64   3e-10
AB040451-1|BAA92928.1|  314|Homo sapiens TOK-1beta protein.            64   3e-10
AB040450-1|BAA92927.1|  322|Homo sapiens TOK-1alpha protein.           64   3e-10

>BC009771-1|AAH09771.1|  314|Homo sapiens BRCA2 and CDKN1A
           interacting protein protein.
          Length = 314

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AY064249-1|AAL55440.1|  314|Homo sapiens BRCA2 and Cip1/p21
           interacting protein, splice variant beta protein.
          Length = 314

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AY064248-1|AAL55439.1|  322|Homo sapiens BRCA2 and Cip1/p21
           interacting protein, splice variant alpha protein.
          Length = 322

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AY064247-2|AAL55438.1|  314|Homo sapiens BRCA2 and Cip1/p21
           interacting protein protein.
          Length = 314

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AY064247-1|AAL55436.1|  322|Homo sapiens BRCA2 and Cip1/p21
           interacting protein protein.
          Length = 322

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AL360176-8|CAI12093.1|  322|Homo sapiens BRCA2 and CDKN1A
           interacting protein protein.
          Length = 322

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AL360176-7|CAI12092.1|  292|Homo sapiens BRCA2 and CDKN1A
           interacting protein protein.
          Length = 292

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AL360176-6|CAI12091.1|  314|Homo sapiens BRCA2 and CDKN1A
           interacting protein protein.
          Length = 314

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AB040451-1|BAA92928.1|  314|Homo sapiens TOK-1beta protein.
          Length = 314

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


>AB040450-1|BAA92927.1|  322|Homo sapiens TOK-1alpha protein.
          Length = 322

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/135 (28%), Positives = 65/135 (48%)
 Frame = +2

Query: 248 EAMFLKSNVDLGGLAQIIISQNYIGSVVKQCLXXXXXXXXXXXXXXXXVFGVTTVVNITK 427
           + +FLK+ V+   L  ++I QN+IGSV+KQ                  VFG  +++N+T+
Sbjct: 79  QQLFLKAPVNTAELTDLLIQQNHIGSVIKQ---TDVSEDSNDDMDEDEVFGFISLLNLTE 135

Query: 428 RKNEPSVAQIRELLTKLSQENADPRTKN*LNIFWXXXXXXXXXXXXKEY*TFLQRLAYPL 607
           RK    V QI+EL+ +  ++N +      L+ F             + +     ++A P+
Sbjct: 136 RKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPM 195

Query: 608 FASLQTELEKAHRKN 652
           +  LQ EL  AHR N
Sbjct: 196 YQQLQKELAGAHRTN 210



 Score = 35.5 bits (78), Expect = 0.17
 Identities = 18/64 (28%), Positives = 36/64 (56%)
 Frame = +3

Query: 69  IKRTRKLTQTAKATKEQDSGSEKDSDFDSDGNYVGEKXLQADFEGRNPEDSDFHGIKQLL 248
           ++R  +  +  +   E D  S+K+ D + +   V ++ +  +FE  +  D+D+ GIK+LL
Sbjct: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDE---VIDEEVNIEFEAYSLSDNDYDGIKKLL 78

Query: 249 RQCF 260
           +Q F
Sbjct: 79  QQLF 82


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 71,787,133
Number of Sequences: 237096
Number of extensions: 1198351
Number of successful extensions: 2914
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2697
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2889
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7591280850
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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