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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Nnor0195
         (560 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CR536548-1|CAG38785.1|  338|Homo sapiens MDH2 protein.                185   1e-46
BC001917-1|AAH01917.1|  338|Homo sapiens malate dehydrogenase 2,...   184   2e-46
AF047470-1|AAC03787.1|  338|Homo sapiens malate dehydrogenase pr...   184   2e-46
DQ402957-1|ABD77290.1|  305|Homo sapiens mitochondrial malate de...   173   3e-43
AC005077-1|AAS07425.1|  316|Homo sapiens unknown protein.             171   1e-42
BC014340-1|AAH14340.1|  234|Homo sapiens LDHAL6A protein protein.      47   5e-05
AY581313-1|AAS93432.1|  332|Homo sapiens lactate dehydrogenase p...    47   5e-05
AK131523-1|BAD18662.1|  332|Homo sapiens protein ( Homo sapiens ...    47   5e-05
BC008735-1|AAH08735.2|  627|Homo sapiens FBXL10 protein protein.       33   0.91 
AK027692-1|BAB55301.1|  653|Homo sapiens protein ( Homo sapiens ...    33   0.91 
AK027440-1|BAB55112.1|  704|Homo sapiens protein ( Homo sapiens ...    33   0.91 
AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.        33   0.91 
AB031230-1|BAA97672.1|  827|Homo sapiens protein containing CXXC...    33   0.91 
M55172-1|AAA62824.1| 2316|Homo sapiens large aggregating cartila...    31   3.7  
S74659-1|AAC60643.2|  102|Homo sapiens aggrecan keratan sulfate ...    29   8.5  

>CR536548-1|CAG38785.1|  338|Homo sapiens MDH2 protein.
          Length = 338

 Score =  185 bits (450), Expect = 1e-46
 Identities = 92/163 (56%), Positives = 118/163 (72%)
 Frame = +1

Query: 70  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 249
           M S  ++P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALVRPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 250 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 429
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 430 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
           NA+IV  +  + AQ+ P+A++ +I NPVNST+PI +EV  K G
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHG 159


>BC001917-1|AAH01917.1|  338|Homo sapiens malate dehydrogenase 2,
           NAD (mitochondrial) protein.
          Length = 338

 Score =  184 bits (448), Expect = 2e-46
 Identities = 92/163 (56%), Positives = 117/163 (71%)
 Frame = +1

Query: 70  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 249
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 250 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 429
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 430 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
           NA+IV  +  + AQ+ P+A++ +I NPVNST+PI +EV  K G
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHG 159


>AF047470-1|AAC03787.1|  338|Homo sapiens malate dehydrogenase
           precursor protein.
          Length = 338

 Score =  184 bits (448), Expect = 2e-46
 Identities = 92/163 (56%), Positives = 117/163 (71%)
 Frame = +1

Query: 70  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 249
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 250 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 429
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 430 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLGKSG 558
           NA+IV  +  + AQ+ P+A++ +I NPVNST+PI +EV  K G
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHG 159


>DQ402957-1|ABD77290.1|  305|Homo sapiens mitochondrial malate
           dehydrogenase 2, NAD protein.
          Length = 305

 Score =  173 bits (422), Expect = 3e-43
 Identities = 85/139 (61%), Positives = 102/139 (73%)
 Frame = +1

Query: 142 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGH 321
           Q N K         IGQPL+LLLK +PLV+RL LYDIA  TPGVAADLSH+ T A V G+
Sbjct: 1   QNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGY 59

Query: 322 KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAII 501
            GPE+L   +K  DVVVIPAGVPRKPGMTRDDLFNTNA+IV  +  + AQ+ P+A++ +I
Sbjct: 60  LGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVI 119

Query: 502 TNPVNSTVPIASEVLGKSG 558
            NPVNST+PI +EV  K G
Sbjct: 120 ANPVNSTIPITAEVFKKHG 138


>AC005077-1|AAS07425.1|  316|Homo sapiens unknown protein.
          Length = 316

 Score =  171 bits (417), Expect = 1e-42
 Identities = 82/125 (65%), Positives = 99/125 (79%)
 Frame = +1

Query: 184 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSAAIKDAD 363
           IGQPL+LLLK +PLV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  D
Sbjct: 14  IGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCD 72

Query: 364 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 543
           VVVIPAGVPRKPGMTRDDLFNTNA+IV  +  + AQ+ P+A++ +I NPVNST+PI +EV
Sbjct: 73  VVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEV 132

Query: 544 LGKSG 558
             K G
Sbjct: 133 FKKHG 137


>BC014340-1|AAH14340.1|  234|Homo sapiens LDHAL6A protein protein.
          Length = 234

 Score = 46.8 bits (106), Expect = 5e-05
 Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 1/144 (0%)
 Frame = +1

Query: 121 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVN 297
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 298 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 477
              K+      ++      ++++V+I AG  +K G TR DL   N SI + +  +I Q +
Sbjct: 70  PFMKMPNIVSSKDYLVTA-NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 478 PKAIVAIITNPVNSTVPIASEVLG 549
           P   + I+TNPV+    +A ++ G
Sbjct: 129 PHCKLLIVTNPVDILTYVAWKLSG 152


>AY581313-1|AAS93432.1|  332|Homo sapiens lactate dehydrogenase
           protein.
          Length = 332

 Score = 46.8 bits (106), Expect = 5e-05
 Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 1/144 (0%)
 Frame = +1

Query: 121 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVN 297
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 298 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 477
              K+      ++      ++++V+I AG  +K G TR DL   N SI + +  +I Q +
Sbjct: 70  PFMKMPNIVSSKDYLVTA-NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 478 PKAIVAIITNPVNSTVPIASEVLG 549
           P   + I+TNPV+    +A ++ G
Sbjct: 129 PHCKLLIVTNPVDILTYVAWKLSG 152


>AK131523-1|BAD18662.1|  332|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43406 fis, clone OCBBF2019823, highly  similar
           to Homo sapiens lactate dehydrogenase A -like (LDHL). ).
          Length = 332

 Score = 46.8 bits (106), Expect = 5e-05
 Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 1/144 (0%)
 Frame = +1

Query: 121 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVN 297
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 298 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 477
              K+      ++      ++++V+I AG  +K G TR DL   N SI + +  +I Q +
Sbjct: 70  PFMKMPNIVSSKDYLVTA-NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 478 PKAIVAIITNPVNSTVPIASEVLG 549
           P   + I+TNPV+    +A ++ G
Sbjct: 129 PHCKLLIVTNPVDILTYVAWKLSG 152


>BC008735-1|AAH08735.2|  627|Homo sapiens FBXL10 protein protein.
          Length = 627

 Score = 32.7 bits (71), Expect = 0.91
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 166 RPPL*SSSVMWWKSSLHHFVQQ 101
           RPPL SS   WW+SSL +F QQ
Sbjct: 125 RPPLGSSLSPWWRSSLTYFQQQ 146


>AK027692-1|BAB55301.1|  653|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14786 fis, clone NT2RP4000737, moderately
           similar to Mus musculus F-box protein FBL10 mRNA. ).
          Length = 653

 Score = 32.7 bits (71), Expect = 0.91
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 166 RPPL*SSSVMWWKSSLHHFVQQ 101
           RPPL SS   WW+SSL +F QQ
Sbjct: 151 RPPLGSSLSPWWRSSLTYFQQQ 172


>AK027440-1|BAB55112.1|  704|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14534 fis, clone NT2RM2000599, weakly similar to
           Homo sapiens F-box protein Lilina (LILINA) mRNA. ).
          Length = 704

 Score = 32.7 bits (71), Expect = 0.91
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 166 RPPL*SSSVMWWKSSLHHFVQQ 101
           RPPL SS   WW+SSL +F QQ
Sbjct: 202 RPPLGSSLSPWWRSSLTYFQQQ 223


>AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.
          Length = 1336

 Score = 32.7 bits (71), Expect = 0.91
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 166 RPPL*SSSVMWWKSSLHHFVQQ 101
           RPPL SS   WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855


>AB031230-1|BAA97672.1|  827|Homo sapiens protein containing CXXC
           domain 2 protein.
          Length = 827

 Score = 32.7 bits (71), Expect = 0.91
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 166 RPPL*SSSVMWWKSSLHHFVQQ 101
           RPPL SS   WW+SSL +F QQ
Sbjct: 358 RPPLGSSLSPWWRSSLTYFQQQ 379


>M55172-1|AAA62824.1| 2316|Homo sapiens large aggregating cartilage
           proteoglycan core protein protein.
          Length = 2316

 Score = 30.7 bits (66), Expect = 3.7
 Identities = 14/44 (31%), Positives = 20/44 (45%)
 Frame = +3

Query: 189 PAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPREHPSQGQRP 320
           P  G  TE  + G  A  +  ++ +P     PFP E PS  + P
Sbjct: 761 PPTGAETEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEP 804


>S74659-1|AAC60643.2|  102|Homo sapiens aggrecan keratan sulfate
           domain protein.
          Length = 102

 Score = 29.5 bits (63), Expect = 8.5
 Identities = 13/41 (31%), Positives = 20/41 (48%)
 Frame = +3

Query: 198 GPSTEAESSGDQAGFIRHSACDPRRRSRPFPREHPSQGQRP 320
           G +TE  + G  A  +  ++ +P     PFP E PS  + P
Sbjct: 1   GAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEP 41


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.315    0.131    0.361 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,001,138
Number of Sequences: 237096
Number of extensions: 2116640
Number of successful extensions: 5258
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4918
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5252
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5646880600
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)

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