Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0001_B20
(337 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U62662-1|AAG10644.1| 387|Homo sapiens chitotriosidase precursor... 48 9e-06
U29615-1|AAC50246.1| 466|Homo sapiens chitotriosidase precursor... 48 9e-06
BC105682-1|AAI05683.1| 466|Homo sapiens chitinase 1 (chitotrios... 48 9e-06
BC105681-1|AAI05682.1| 466|Homo sapiens chitinase 1 (chitotrios... 48 9e-06
BC105680-1|AAI05681.1| 466|Homo sapiens chitinase 1 (chitotrios... 48 9e-06
BC103695-1|AAI03696.1| 466|Homo sapiens chitinase 1 (chitotrios... 48 9e-06
BC069614-1|AAH69614.1| 454|Homo sapiens CHIT1 protein protein. 48 9e-06
AB208783-1|BAD92020.1| 742|Homo sapiens Oviduct-specific glycop... 39 0.003
AL513202-4|CAH70803.1| 476|Homo sapiens eosinophil chemotactic ... 38 0.010
AL356387-8|CAI19265.1| 476|Homo sapiens eosinophil chemotactic ... 38 0.010
AF290004-1|AAG60019.1| 476|Homo sapiens acidic mammalian chitin... 38 0.010
Y08374-1|CAA69661.1| 383|Homo sapiens GP-39 cartilage protein p... 37 0.018
U58010-1|AAB04126.1| 678|Homo sapiens oviductal glycoprotein pr... 37 0.018
U09550-1|AAA86946.1| 678|Homo sapiens oviductal glycoprotein pr... 37 0.018
M80927-1|AAA16074.1| 383|Homo sapiens glycoprotein protein. 37 0.018
BT007223-1|AAP35887.1| 383|Homo sapiens chitinase 3-like 1 (car... 37 0.018
BC126177-1|AAI26178.1| 678|Homo sapiens oviductal glycoprotein ... 37 0.018
BC039132-1|AAH39132.1| 383|Homo sapiens chitinase 3-like 1 (car... 37 0.018
BC038354-1|AAH38354.1| 383|Homo sapiens chitinase 3-like 1 (car... 37 0.018
BC008568-1|AAH08568.1| 383|Homo sapiens chitinase 3-like 1 (car... 37 0.018
AY189737-1|AAO37816.1| 678|Homo sapiens oviductin protein. 37 0.018
AL390195-3|CAC36039.1| 678|Homo sapiens oviductal glycoprotein ... 37 0.018
BC046199-1|AAH46199.1| 109|Homo sapiens family with sequence si... 28 8.2
BC036940-1|AAH36940.1| 542|Homo sapiens ZCCHC7 protein protein. 28 8.2
BC005990-1|AAH05990.1| 405|Homo sapiens Unknown (protein for IM... 28 8.2
AL512604-1|CAI12725.2| 543|Homo sapiens zinc finger, CCHC domai... 28 8.2
AL357493-4|CAI14139.1| 120|Homo sapiens family with sequence si... 28 8.2
AL357493-3|CAI14138.1| 120|Homo sapiens family with sequence si... 28 8.2
AL357493-2|CAI14136.1| 149|Homo sapiens family with sequence si... 28 8.2
AL357493-1|CAI14137.1| 109|Homo sapiens family with sequence si... 28 8.2
AL158155-1|CAI13846.2| 543|Homo sapiens zinc finger, CCHC domai... 28 8.2
AK074608-1|BAC11087.1| 391|Homo sapiens protein ( Homo sapiens ... 28 8.2
AK026264-1|BAB15418.1| 454|Homo sapiens protein ( Homo sapiens ... 28 8.2
AF161349-1|AAF28909.1| 107|Homo sapiens HSPC086 protein. 28 8.2
>U62662-1|AAG10644.1| 387|Homo sapiens chitotriosidase precursor
protein.
Length = 387
Score = 47.6 bits (108), Expect = 9e-06
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
S +K++CY+ + + R+ +AR LP DL+P+L CTHL+Y AG+
Sbjct: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGM 61
>U29615-1|AAC50246.1| 466|Homo sapiens chitotriosidase precursor
protein.
Length = 466
Score = 47.6 bits (108), Expect = 9e-06
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
S +K++CY+ + + R+ +AR LP DL+P+L CTHL+Y AG+
Sbjct: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGM 61
>BC105682-1|AAI05683.1| 466|Homo sapiens chitinase 1
(chitotriosidase) protein.
Length = 466
Score = 47.6 bits (108), Expect = 9e-06
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
S +K++CY+ + + R+ +AR LP DL+P+L CTHL+Y AG+
Sbjct: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGM 61
>BC105681-1|AAI05682.1| 466|Homo sapiens chitinase 1
(chitotriosidase) protein.
Length = 466
Score = 47.6 bits (108), Expect = 9e-06
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
S +K++CY+ + + R+ +AR LP DL+P+L CTHL+Y AG+
Sbjct: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGM 61
>BC105680-1|AAI05681.1| 466|Homo sapiens chitinase 1
(chitotriosidase) protein.
Length = 466
Score = 47.6 bits (108), Expect = 9e-06
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
S +K++CY+ + + R+ +AR LP DL+P+L CTHL+Y AG+
Sbjct: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGM 61
>BC103695-1|AAI03696.1| 466|Homo sapiens chitinase 1
(chitotriosidase) protein.
Length = 466
Score = 47.6 bits (108), Expect = 9e-06
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
S +K++CY+ + + R+ +AR LP DL+P+L CTHL+Y AG+
Sbjct: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGM 61
>BC069614-1|AAH69614.1| 454|Homo sapiens CHIT1 protein protein.
Length = 454
Score = 47.6 bits (108), Expect = 9e-06
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
S +K++CY+ + + R+ +AR LP DL+P+L CTHL+Y AG+
Sbjct: 8 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGM 49
>AB208783-1|BAD92020.1| 742|Homo sapiens Oviduct-specific
glycoprotein precursor variant protein.
Length = 742
Score = 39.1 bits (87), Expect = 0.003
Identities = 17/46 (36%), Positives = 29/46 (63%)
Frame = +1
Query: 118 PSSQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
P + K++CY+ + ++ R A +LP DL+P L CTHL++ A +
Sbjct: 60 PGAAHKLVCYFTNWAHSRPGPASILPHDLDPFL--CTHLIFAFASM 103
>AL513202-4|CAH70803.1| 476|Homo sapiens eosinophil chemotactic
cytokine (CHIA) protein.
Length = 476
Score = 37.5 bits (83), Expect = 0.010
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQADTYKMVSLNE 291
S ++ CY+ + + R R +P +++P L CTHL+Y AG Q + + N+
Sbjct: 20 SAYQLTCYFTNWAQYRPGLGRFMPDNIDPCL--CTHLIYAFAGRQNNEITTIEWND 73
>AL356387-8|CAI19265.1| 476|Homo sapiens eosinophil chemotactic
cytokine (CHIA) protein.
Length = 476
Score = 37.5 bits (83), Expect = 0.010
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQADTYKMVSLNE 291
S ++ CY+ + + R R +P +++P L CTHL+Y AG Q + + N+
Sbjct: 20 SAYQLTCYFTNWAQYRPGLGRFMPDNIDPCL--CTHLIYAFAGRQNNEITTIEWND 73
>AF290004-1|AAG60019.1| 476|Homo sapiens acidic mammalian chitinase
precursor protein.
Length = 476
Score = 37.5 bits (83), Expect = 0.010
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQADTYKMVSLNE 291
S ++ CY+ + + R R +P +++P L CTHL+Y AG Q + + N+
Sbjct: 20 SAYQLTCYFTNWAQYRPGLGRFMPDNIDPCL--CTHLIYAFAGRQNNEITTIEWND 73
>Y08374-1|CAA69661.1| 383|Homo sapiens GP-39 cartilage protein
protein.
Length = 383
Score = 36.7 bits (81), Expect = 0.018
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQAD 264
S K++CYY S S RE P L+ L CTH++Y A I D
Sbjct: 20 SAYKLVCYYTSWSQYREGDGSCFPDALDRFL--CTHIIYSFANISND 64
>U58010-1|AAB04126.1| 678|Homo sapiens oviductal glycoprotein
protein.
Length = 678
Score = 36.7 bits (81), Expect = 0.018
Identities = 16/41 (39%), Positives = 27/41 (65%)
Frame = +1
Query: 133 KVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
K++CY+ + ++ R A +LP DL+P L CTHL++ A +
Sbjct: 23 KLVCYFTNWAHSRPGPASILPHDLDPFL--CTHLIFAFASM 61
>U09550-1|AAA86946.1| 678|Homo sapiens oviductal glycoprotein
protein.
Length = 678
Score = 36.7 bits (81), Expect = 0.018
Identities = 16/41 (39%), Positives = 27/41 (65%)
Frame = +1
Query: 133 KVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
K++CY+ + ++ R A +LP DL+P L CTHL++ A +
Sbjct: 23 KLVCYFTNWAHSRPGPASILPHDLDPFL--CTHLIFAFASM 61
>M80927-1|AAA16074.1| 383|Homo sapiens glycoprotein protein.
Length = 383
Score = 36.7 bits (81), Expect = 0.018
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQAD 264
S K++CYY S S RE P L+ L CTH++Y A I D
Sbjct: 20 SAYKLVCYYTSWSQYREGDGSCFPDALDRFL--CTHIIYSFANISND 64
>BT007223-1|AAP35887.1| 383|Homo sapiens chitinase 3-like 1
(cartilage glycoprotein-39) protein.
Length = 383
Score = 36.7 bits (81), Expect = 0.018
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQAD 264
S K++CYY S S RE P L+ L CTH++Y A I D
Sbjct: 20 SAYKLVCYYTSWSQYREGDGSCFPDALDRFL--CTHIIYSFANISND 64
>BC126177-1|AAI26178.1| 678|Homo sapiens oviductal glycoprotein 1,
120kDa (mucin 9, oviductin) protein.
Length = 678
Score = 36.7 bits (81), Expect = 0.018
Identities = 16/41 (39%), Positives = 27/41 (65%)
Frame = +1
Query: 133 KVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
K++CY+ + ++ R A +LP DL+P L CTHL++ A +
Sbjct: 23 KLVCYFTNWAHSRPGPASILPHDLDPFL--CTHLIFAFASM 61
>BC039132-1|AAH39132.1| 383|Homo sapiens chitinase 3-like 1
(cartilage glycoprotein-39) protein.
Length = 383
Score = 36.7 bits (81), Expect = 0.018
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQAD 264
S K++CYY S S RE P L+ L CTH++Y A I D
Sbjct: 20 SAYKLVCYYTSWSQYREGDGSCFPDALDRFL--CTHIIYSFANISND 64
>BC038354-1|AAH38354.1| 383|Homo sapiens chitinase 3-like 1
(cartilage glycoprotein-39) protein.
Length = 383
Score = 36.7 bits (81), Expect = 0.018
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQAD 264
S K++CYY S S RE P L+ L CTH++Y A I D
Sbjct: 20 SAYKLVCYYTSWSQYREGDGSCFPDALDRFL--CTHIIYSFANISND 64
>BC008568-1|AAH08568.1| 383|Homo sapiens chitinase 3-like 1
(cartilage glycoprotein-39) protein.
Length = 383
Score = 36.7 bits (81), Expect = 0.018
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +1
Query: 124 SQSKVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGIQAD 264
S K++CYY S S RE P L+ L CTH++Y A I D
Sbjct: 20 SAYKLVCYYTSWSQYREGDGSCFPDALDRFL--CTHIIYSFANISND 64
>AY189737-1|AAO37816.1| 678|Homo sapiens oviductin protein.
Length = 678
Score = 36.7 bits (81), Expect = 0.018
Identities = 16/41 (39%), Positives = 27/41 (65%)
Frame = +1
Query: 133 KVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
K++CY+ + ++ R A +LP DL+P L CTHL++ A +
Sbjct: 23 KLVCYFTNWAHSRPGPASILPHDLDPFL--CTHLIFAFASM 61
>AL390195-3|CAC36039.1| 678|Homo sapiens oviductal glycoprotein 1,
120kDa (mucin 9, oviductin) protein.
Length = 678
Score = 36.7 bits (81), Expect = 0.018
Identities = 16/41 (39%), Positives = 27/41 (65%)
Frame = +1
Query: 133 KVLCYYDSKSYIRESQARMLPTDLEPALSFCTHLLYKSAGI 255
K++CY+ + ++ R A +LP DL+P L CTHL++ A +
Sbjct: 23 KLVCYFTNWAHSRPGPASILPHDLDPFL--CTHLIFAFASM 61
>BC046199-1|AAH46199.1| 109|Homo sapiens family with sequence
similarity 72, member B protein.
Length = 109
Score = 27.9 bits (59), Expect = 8.2
Identities = 13/46 (28%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Frame = +2
Query: 176 LKHVCCLRTWSLLFRSAPICCTN-LPASKLTHIKWFHSMRIWTIDR 310
LK + CL+ +++ + C++ LP+ H FHS ++ I+R
Sbjct: 29 LKDIACLKCGNIVGYHVIVPCSSCLPSCNNGHFWMFHSQAVYDINR 74
>BC036940-1|AAH36940.1| 542|Homo sapiens ZCCHC7 protein protein.
Length = 542
Score = 27.9 bits (59), Expect = 8.2
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +1
Query: 118 PSSQSKVLCYYDSKSYIRESQARM 189
PS S +CYYD K I+E + R+
Sbjct: 370 PSPVSPFICYYDDKYEIQEREKRL 393
>BC005990-1|AAH05990.1| 405|Homo sapiens Unknown (protein for
IMAGE:4046616) protein.
Length = 405
Score = 27.9 bits (59), Expect = 8.2
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +1
Query: 118 PSSQSKVLCYYDSKSYIRESQARM 189
PS S +CYYD K I+E + R+
Sbjct: 371 PSPVSPFICYYDDKYEIQEREKRL 394
>AL512604-1|CAI12725.2| 543|Homo sapiens zinc finger, CCHC domain
containing 7 protein.
Length = 543
Score = 27.9 bits (59), Expect = 8.2
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +1
Query: 118 PSSQSKVLCYYDSKSYIRESQARM 189
PS S +CYYD K I+E + R+
Sbjct: 371 PSPVSPFICYYDDKYEIQEREKRL 394
>AL357493-4|CAI14139.1| 120|Homo sapiens family with sequence
similarity 72, member B protein.
Length = 120
Score = 27.9 bits (59), Expect = 8.2
Identities = 13/46 (28%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Frame = +2
Query: 176 LKHVCCLRTWSLLFRSAPICCTN-LPASKLTHIKWFHSMRIWTIDR 310
LK + CL+ +++ + C++ LP+ H FHS ++ I+R
Sbjct: 40 LKDIACLKCGNIVGYHVIVPCSSCLPSCNNGHFWMFHSQAVYDINR 85
>AL357493-3|CAI14138.1| 120|Homo sapiens family with sequence
similarity 72, member B protein.
Length = 120
Score = 27.9 bits (59), Expect = 8.2
Identities = 13/46 (28%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Frame = +2
Query: 176 LKHVCCLRTWSLLFRSAPICCTN-LPASKLTHIKWFHSMRIWTIDR 310
LK + CL+ +++ + C++ LP+ H FHS ++ I+R
Sbjct: 40 LKDIACLKCGNIVGYHVIVPCSSCLPSCNNGHFWMFHSQAVYDINR 85
>AL357493-2|CAI14136.1| 149|Homo sapiens family with sequence
similarity 72, member B protein.
Length = 149
Score = 27.9 bits (59), Expect = 8.2
Identities = 13/46 (28%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Frame = +2
Query: 176 LKHVCCLRTWSLLFRSAPICCTN-LPASKLTHIKWFHSMRIWTIDR 310
LK + CL+ +++ + C++ LP+ H FHS ++ I+R
Sbjct: 69 LKDIACLKCGNIVGYHVIVPCSSCLPSCNNGHFWMFHSQAVYDINR 114
>AL357493-1|CAI14137.1| 109|Homo sapiens family with sequence
similarity 72, member B protein.
Length = 109
Score = 27.9 bits (59), Expect = 8.2
Identities = 13/46 (28%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Frame = +2
Query: 176 LKHVCCLRTWSLLFRSAPICCTN-LPASKLTHIKWFHSMRIWTIDR 310
LK + CL+ +++ + C++ LP+ H FHS ++ I+R
Sbjct: 29 LKDIACLKCGNIVGYHVIVPCSSCLPSCNNGHFWMFHSQAVYDINR 74
>AL158155-1|CAI13846.2| 543|Homo sapiens zinc finger, CCHC domain
containing 7 protein.
Length = 543
Score = 27.9 bits (59), Expect = 8.2
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +1
Query: 118 PSSQSKVLCYYDSKSYIRESQARM 189
PS S +CYYD K I+E + R+
Sbjct: 371 PSPVSPFICYYDDKYEIQEREKRL 394
>AK074608-1|BAC11087.1| 391|Homo sapiens protein ( Homo sapiens
cDNA FLJ90127 fis, clone HEMBB1000106, weakly similar to
CELLULAR NUCLEIC ACID BINDING PROTEIN. ).
Length = 391
Score = 27.9 bits (59), Expect = 8.2
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +1
Query: 118 PSSQSKVLCYYDSKSYIRESQARM 189
PS S +CYYD K I+E + R+
Sbjct: 219 PSPVSPFICYYDDKYEIQEREKRL 242
>AK026264-1|BAB15418.1| 454|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22611 fis, clone HSI04961. ).
Length = 454
Score = 27.9 bits (59), Expect = 8.2
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +1
Query: 118 PSSQSKVLCYYDSKSYIRESQARM 189
PS S +CYYD K I+E + R+
Sbjct: 371 PSPVSPFICYYDDKYEIQEREKRL 394
>AF161349-1|AAF28909.1| 107|Homo sapiens HSPC086 protein.
Length = 107
Score = 27.9 bits (59), Expect = 8.2
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +1
Query: 118 PSSQSKVLCYYDSKSYIRESQARM 189
PS S +CYYD K I+E + R+
Sbjct: 32 PSPVSPFICYYDDKYEIQEREKRL 55
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 46,558,870
Number of Sequences: 237096
Number of extensions: 862488
Number of successful extensions: 1684
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 1650
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1677
length of database: 76,859,062
effective HSP length: 80
effective length of database: 57,891,382
effective search space used: 1794632842
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -