Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV40969
(752 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF275948-1|AAF86276.1| 2261|Homo sapiens ABCA1 protein. 109 8e-24
AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette, s... 109 1e-23
AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette, s... 109 1e-23
AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette tr... 109 1e-23
AF287262-1|AAK43526.1| 2261|Homo sapiens ATP-binding cassette 1 ... 109 1e-23
AF285167-1|AAF98175.1| 2261|Homo sapiens ATP-binding cassette tr... 109 1e-23
AF165281-1|AAD49849.1| 2201|Homo sapiens ATP cassette binding tr... 109 1e-23
AB208839-1|BAD92076.1| 403|Homo sapiens ATP-binding cassette, s... 109 1e-23
AB055982-1|BAB63210.1| 2261|Homo sapiens ABCA1 protein. 109 1e-23
BC008755-1|AAH08755.1| 867|Homo sapiens ABCA2 protein protein. 109 1e-23
AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette, ... 109 1e-23
AL807752-20|CAI12766.1| 226|Homo sapiens ATP-binding cassette, ... 109 1e-23
AL162060-1|CAB82398.1| 373|Homo sapiens hypothetical protein pr... 109 1e-23
AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2 p... 109 1e-23
AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2 p... 109 1e-23
AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette su... 109 1e-23
AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein. 109 1e-23
X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein. 107 4e-23
U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein. 107 4e-23
DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette, s... 107 4e-23
AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein p... 107 4e-23
AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane ... 107 4e-23
Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein. 106 7e-23
U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette tran... 106 7e-23
AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter pro... 106 7e-23
AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein p... 106 7e-23
AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette tr... 105 1e-22
AL137481-1|CAB70762.1| 269|Homo sapiens hypothetical protein pr... 103 9e-22
AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member ... 103 9e-22
AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7 p... 103 9e-22
AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transpor... 103 9e-22
AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein. 103 9e-22
AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subf... 83 1e-15
AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette tr... 83 1e-15
AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette tr... 83 1e-15
AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein. 83 1e-15
AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein. 79 2e-14
AK131360-1|BAD18512.1| 1186|Homo sapiens mRNA. protein. 79 2e-14
AK128516-1|BAC87475.1| 788|Homo sapiens protein ( Homo sapiens ... 79 2e-14
AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette tr... 79 2e-14
AK056533-1|BAB71208.1| 865|Homo sapiens protein ( Homo sapiens ... 75 4e-13
AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant... 69 2e-11
AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9... 68 3e-11
AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette su... 68 3e-11
AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette su... 68 3e-11
BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein. 67 7e-11
AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein. 67 7e-11
BX640746-1|CAE45856.1| 431|Homo sapiens hypothetical protein pr... 64 5e-10
AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5... 64 5e-10
AJ512612-1|CAD54757.1| 925|Homo sapiens ABCA5 transporter protein. 64 5e-10
AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette pr... 64 5e-10
AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens ... 64 7e-10
AK130814-1|BAC85435.1| 546|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AL807752-19|CAI12765.1| 184|Homo sapiens ATP-binding cassette, ... 62 3e-09
AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette su... 61 4e-09
AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette su... 61 4e-09
AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A1... 61 4e-09
AL080207-1|CAB45776.1| 196|Homo sapiens hypothetical protein pr... 61 4e-09
AC114780-1|AAY24230.1| 182|Homo sapiens unknown protein. 61 4e-09
BC051320-1|AAH51320.1| 419|Homo sapiens ABCA10 protein protein. 60 6e-09
AK074491-1|BAC11021.1| 483|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AK057068-1|BAB71359.1| 856|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6 p... 56 1e-07
AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6 p... 56 1e-07
BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein. 55 2e-07
BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein. 55 2e-07
AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6... 55 2e-07
AK097296-1|BAC04994.1| 815|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AK091270-1|BAC03623.1| 293|Homo sapiens protein ( Homo sapiens ... 54 4e-07
U18236-1|AAA84437.2| 131|Homo sapiens ATP-binding cassette prot... 52 2e-06
AK058170-1|BAB71700.1| 364|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AB067475-1|BAB67781.1| 737|Homo sapiens KIAA1888 protein protein. 52 2e-06
AF165306-1|AAD49852.1| 849|Homo sapiens ATP cassette binding tr... 45 3e-04
BC113657-1|AAI13658.1| 673|Homo sapiens ATP-binding cassette, s... 35 0.27
AF351824-1|AAK84663.1| 672|Homo sapiens sterolin-2 protein. 35 0.27
AF324494-1|AAK84078.1| 673|Homo sapiens sterolin-2 protein. 35 0.27
AF320294-1|AAG40004.1| 673|Homo sapiens ABCG8 protein. 35 0.27
AC108476-2|AAY24011.1| 673|Homo sapiens unknown protein. 35 0.27
CR589949-2|CAM12888.1| 584|Homo sapiens intracisternal A partic... 34 0.63
BX664740-2|CAM12889.1| 584|Homo sapiens intracisternal A partic... 34 0.63
BT007451-1|AAP36119.1| 623|Homo sapiens ATP-binding cassette, s... 34 0.63
BC001661-1|AAH01661.1| 623|Homo sapiens ATP-binding cassette, s... 34 0.63
AL604028-4|CAM12886.1| 584|Homo sapiens intracisternal A partic... 34 0.63
AJ005016-1|CAA06290.1| 550|Homo sapiens ABC transporter protein. 34 0.63
AF261092-1|AAG13903.1| 623|Homo sapiens iron inhibited ABC tran... 34 0.63
AF261091-1|AAG13902.1| 623|Homo sapiens iron inhibited ABC tran... 34 0.63
AF156857-1|AAD39007.1| 584|Homo sapiens actin-binding protein p... 34 0.63
AC021097-3|AAS00379.1| 623|Homo sapiens unknown protein. 34 0.63
AC021097-2|AAS00378.1| 634|Homo sapiens unknown protein. 34 0.63
BC112069-1|AAI12070.1| 66|Homo sapiens ABCA11 protein protein. 33 1.1
BC105084-1|AAI05085.1| 66|Homo sapiens ABCA11 protein protein. 33 1.1
BC099730-1|AAH99730.1| 66|Homo sapiens ABCA11 protein protein. 33 1.1
BC098259-1|AAH98259.1| 66|Homo sapiens ABCA11 protein protein. 33 1.1
BC098116-1|AAH98116.1| 66|Homo sapiens ABCA11 protein protein. 33 1.1
AK024359-1|BAB14895.1| 156|Homo sapiens protein ( Homo sapiens ... 33 1.1
AC092574-2|AAY41037.1| 156|Homo sapiens unknown protein. 33 1.1
BC041091-1|AAH41091.1| 646|Homo sapiens ATP-binding cassette, s... 32 2.5
AJ308237-1|CAC87131.1| 646|Homo sapiens ABC transporter protein. 32 2.5
AJ300465-1|CAC17140.1| 627|Homo sapiens putative white family A... 32 2.5
AK095260-1|BAC04513.1| 273|Homo sapiens protein ( Homo sapiens ... 31 4.5
BC150263-1|AAI50264.1| 1261|Homo sapiens cordon-bleu homolog (mo... 31 5.9
BC045771-1|AAH45771.1| 1146|Homo sapiens COBL protein protein. 31 5.9
AL713786-1|CAD28543.1| 803|Homo sapiens hypothetical protein pr... 31 5.9
AK092415-1|BAC03881.1| 703|Homo sapiens protein ( Homo sapiens ... 31 5.9
AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump p... 31 5.9
AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump p... 31 5.9
AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein. 31 5.9
AB014533-1|BAA31608.1| 1316|Homo sapiens KIAA0633 protein protein. 31 5.9
DQ996467-1|ABI97388.1| 655|Homo sapiens ATP-binding cassette, s... 30 7.8
BC125226-1|AAI25227.1| 639|Homo sapiens FGD6 protein protein. 30 7.8
BC125225-1|AAI25226.1| 639|Homo sapiens FGD6 protein protein. 30 7.8
BC092408-1|AAH92408.1| 611|Homo sapiens ABCG2 protein protein. 30 7.8
BC021281-1|AAH21281.1| 655|Homo sapiens ATP-binding cassette, s... 30 7.8
BC013319-1|AAH13319.1| 376|Homo sapiens FGD6 protein protein. 30 7.8
AY333756-1|AAQ92942.1| 655|Homo sapiens ATP-binding cassette su... 30 7.8
AY333755-1|AAQ92941.1| 655|Homo sapiens mutant ATP-binding cass... 30 7.8
AY288307-1|AAP31310.1| 541|Homo sapiens ATP-binding cassette su... 30 7.8
AY017168-1|AAG52982.1| 655|Homo sapiens ABC transporter ABCG2 p... 30 7.8
AK128492-1|BAC87464.1| 1053|Homo sapiens protein ( Homo sapiens ... 30 7.8
AK124904-1|BAC85990.1| 1430|Homo sapiens protein ( Homo sapiens ... 30 7.8
AK002045-1|BAA92052.1| 432|Homo sapiens protein ( Homo sapiens ... 30 7.8
AF463519-1|AAO14617.1| 655|Homo sapiens ATP-binding cassette pr... 30 7.8
AF098951-1|AAC97367.1| 655|Homo sapiens breast cancer resistanc... 30 7.8
AC097484-1|AAY40902.1| 607|Homo sapiens unknown protein. 30 7.8
AB056867-1|BAB39212.1| 655|Homo sapiens Breast Cancer Resistanc... 30 7.8
AB051855-1|BAB46933.1| 655|Homo sapiens ATP-binding cassette su... 30 7.8
AB037783-1|BAA92600.1| 699|Homo sapiens KIAA1362 protein protein. 30 7.8
>AF275948-1|AAF86276.1| 2261|Homo sapiens ABCA1 protein.
Length = 2261
Score = 109 bits (263), Expect = 8e-24
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 1941 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNXNSILSNIHEVHQNMGYCPQFDAITEL 2000
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 2001 LTGREHVEFFALLRGVPEKEVGKV 2024
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 932 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 991
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 992 EHIWFYARLKGLSEK 1006
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+LG V + +K S G KRK+ST FLDEPTTGMDP ++R +W S
Sbjct: 2031 KLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSV 2090
Query: 451 VGGGRT 468
V GR+
Sbjct: 2091 VKEGRS 2096
Score = 55.2 bits (127), Expect = 2e-07
Identities = 22/42 (52%), Positives = 34/42 (80%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRD 634
C+++ +MVNGR CLGS+QHLK++F GYTIV++ +G++ D
Sbjct: 2111 CTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRI-AGSNPD 2151
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 1029 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 1072
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2097 VVLTSHSMEECEAL 2110
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 1100 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 1158
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 1159 SQSSSDAGLGSDHES 1173
>AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), memberisiae) protein.
Length = 2261
Score = 109 bits (262), Expect = 1e-23
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 1941 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITEL 2000
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 2001 LTGREHVEFFALLRGVPEKEVGKV 2024
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 932 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 991
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 992 EHIWFYARLKGLSEK 1006
Score = 57.2 bits (132), Expect = 6e-08
Identities = 27/76 (35%), Positives = 43/76 (56%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C+++ +MVNGR CLGS+QHLK++F GYTIV++ + D+ + + F
Sbjct: 2111 CTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGS---NPDLKPVQDFFGLAFPGSV 2167
Query: 689 LVETYLGMSTYHVSSA 736
L E + M Y + S+
Sbjct: 2168 LKEKHRNMLQYQLPSS 2183
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+LG V + +K S G KRK+ST FLDEPTTGMDP ++R +W S
Sbjct: 2031 KLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSV 2090
Query: 451 VGGGRT 468
V GR+
Sbjct: 2091 VKEGRS 2096
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 1029 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 1072
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2097 VVLTSHSMEECEAL 2110
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 1100 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 1158
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 1159 SQSSSDAGLGSDHES 1173
>AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), memberog, Drosophila) protein.
Length = 2261
Score = 109 bits (262), Expect = 1e-23
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 1941 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITEL 2000
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 2001 LTGREHVEFFALLRGVPEKEVGKV 2024
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 932 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 991
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 992 EHIWFYARLKGLSEK 1006
Score = 57.2 bits (132), Expect = 6e-08
Identities = 27/76 (35%), Positives = 43/76 (56%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C+++ +MVNGR CLGS+QHLK++F GYTIV++ + D+ + + F
Sbjct: 2111 CTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGS---NPDLKPVQDFFGLAFPGSV 2167
Query: 689 LVETYLGMSTYHVSSA 736
L E + M Y + S+
Sbjct: 2168 LKEKHRNMLQYQLPSS 2183
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+LG V + +K S G KRK+ST FLDEPTTGMDP ++R +W S
Sbjct: 2031 KLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSV 2090
Query: 451 VGGGRT 468
V GR+
Sbjct: 2091 VKEGRS 2096
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 1029 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 1072
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2097 VVLTSHSMEECEAL 2110
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 1100 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 1158
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 1159 SQSSSDAGLGSDHES 1173
>AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette
transporter-1 (ABC-1) protein.
Length = 2201
Score = 109 bits (262), Expect = 1e-23
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 1881 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNRNSILSNIHEVHQNMGYCPQFDAITEL 1940
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 1941 LTGREHVEFFALLRGVPEKEVGKV 1964
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 872 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 931
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 932 EHIWFYARLKGLSEK 946
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+LG V + +K S G KRK+ST FLDEPTTGMDP ++R +W S
Sbjct: 1971 KLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSV 2030
Query: 451 VGGGRT 468
V GR+
Sbjct: 2031 VKEGRS 2036
Score = 55.2 bits (127), Expect = 2e-07
Identities = 22/42 (52%), Positives = 34/42 (80%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRD 634
C+++ +MVNGR CLGS+QHLK++F GYTIV++ +G++ D
Sbjct: 2051 CTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRI-AGSNPD 2091
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 969 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 1012
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2037 VVLTSHSMEECEAL 2050
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 1040 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 1098
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 1099 SQSSSDAGLGSDHES 1113
>AF287262-1|AAK43526.1| 2261|Homo sapiens ATP-binding cassette 1
sub-family A member 1 protein.
Length = 2261
Score = 109 bits (262), Expect = 1e-23
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 1941 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITEL 2000
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 2001 LTGREHVEFFALLRGVPEKEVGKV 2024
Score = 62.5 bits (145), Expect = 2e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 932 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 991
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 992 EHIWFYARLKGLSKK 1006
Score = 57.2 bits (132), Expect = 6e-08
Identities = 27/76 (35%), Positives = 43/76 (56%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C+++ +MVNGR CLGS+QHLK++F GYTIV++ + D+ + + F
Sbjct: 2111 CTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGS---NPDLKPVQDFFGLAFPGSV 2167
Query: 689 LVETYLGMSTYHVSSA 736
L E + M Y + S+
Sbjct: 2168 LKEKHRNMLQYQLPSS 2183
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+LG V + +K S G KRK+ST FLDEPTTGMDP ++R +W S
Sbjct: 2031 KLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSV 2090
Query: 451 VGGGRT 468
V GR+
Sbjct: 2091 VKEGRS 2096
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 1029 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 1072
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2097 VVLTSHSMEECEAL 2110
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 1100 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 1158
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 1159 SQSSSDAGLGSDHES 1173
>AF285167-1|AAF98175.1| 2261|Homo sapiens ATP-binding cassette
transporter 1 protein.
Length = 2261
Score = 109 bits (262), Expect = 1e-23
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 1941 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITEL 2000
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 2001 LTGREHVEFFALLRGVPEKEVGKV 2024
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 932 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 991
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 992 EHIWFYARLKGLSEK 1006
Score = 57.2 bits (132), Expect = 6e-08
Identities = 27/76 (35%), Positives = 43/76 (56%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C+++ +MVNGR CLGS+QHLK++F GYTIV++ + D+ + + F
Sbjct: 2111 CTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGS---NPDLKPVQDFFGLAFPGSV 2167
Query: 689 LVETYLGMSTYHVSSA 736
L E + M Y + S+
Sbjct: 2168 LKEKHRNMLQYQLPSS 2183
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+LG V + +K S G KRK+ST FLDEPTTGMDP ++R +W S
Sbjct: 2031 KLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSV 2090
Query: 451 VGGGRT 468
V GR+
Sbjct: 2091 VKEGRS 2096
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 1029 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 1072
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2097 VVLTSHSMEECEAL 2110
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 1100 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 1158
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 1159 SQSSSDAGLGSDHES 1173
>AF165281-1|AAD49849.1| 2201|Homo sapiens ATP cassette binding
transporter 1 protein.
Length = 2201
Score = 109 bits (262), Expect = 1e-23
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 1881 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNRNSILSNIHEVHQNMGYCPQFDAITEL 1940
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 1941 LTGREHVEFFALLRGVPEKEVGKV 1964
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 872 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 931
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 932 EHIWFYARLKGLSEK 946
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+LG V + +K S G KRK+ST FLDEPTTGMDP ++R +W S
Sbjct: 1971 KLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSV 2030
Query: 451 VGGGRT 468
V GR+
Sbjct: 2031 VKEGRS 2036
Score = 55.2 bits (127), Expect = 2e-07
Identities = 22/42 (52%), Positives = 34/42 (80%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRD 634
C+++ +MVNGR CLGS+QHLK++F GYTIV++ +G++ D
Sbjct: 2051 CTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRI-AGSNPD 2091
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 969 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 1012
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2037 VVLTSHSMEECEAL 2050
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 1040 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 1098
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 1099 SQSSSDAGLGSDHES 1113
>AB208839-1|BAD92076.1| 403|Homo sapiens ATP-binding cassette,
sub-family A member 1 variant protein.
Length = 403
Score = 109 bits (262), Expect = 1e-23
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 259 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITEL 318
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 319 LTGREHVEFFALLRGVPEKEVGKV 342
>AB055982-1|BAB63210.1| 2261|Homo sapiens ABCA1 protein.
Length = 2261
Score = 109 bits (262), Expect = 1e-23
Identities = 48/84 (57%), Positives = 68/84 (80%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGK+STF+MLTGD V+ GDA ++ +S+ +++ +VH+ +GYCPQFDA+ +
Sbjct: 1941 CFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITEL 2000
Query: 182 LTARETLQIFCLLRGIPQR-VGDV 250
LT RE ++ F LLRG+P++ VG V
Sbjct: 2001 LTGREHVEFFALLRGVPEKEVGKV 2024
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 932 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 991
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 992 EHIWFYARLKGLSEK 1006
Score = 57.2 bits (132), Expect = 6e-08
Identities = 27/76 (35%), Positives = 43/76 (56%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C+++ +MVNGR CLGS+QHLK++F GYTIV++ + D+ + + F
Sbjct: 2111 CTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGS---NPDLKPVQDFFGLAFPGSV 2167
Query: 689 LVETYLGMSTYHVSSA 736
L E + M Y + S+
Sbjct: 2168 LKEKHRNMLQYQLPSS 2183
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+LG V + +K S G KRK+ST FLDEPTTGMDP ++R +W S
Sbjct: 2031 KLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSV 2090
Query: 451 VGGGRT 468
V GR+
Sbjct: 2091 VKEGRS 2096
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 1029 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 1072
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2097 VVLTSHSMEECEAL 2110
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 1100 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 1158
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 1159 SQSSSDAGLGSDHES 1173
>BC008755-1|AAH08755.1| 867|Homo sapiens ABCA2 protein protein.
Length = 867
Score = 109 bits (261), Expect = 1e-23
Identities = 50/76 (65%), Positives = 59/76 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTF+MLTGD + G+A V+GHSV + V + +GYCPQ DALFD
Sbjct: 514 CFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDE 573
Query: 182 LTARETLQIFCLLRGI 229
LTARE LQ++ LRGI
Sbjct: 574 LTAREHLQLYTRLRGI 589
Score = 61.7 bits (143), Expect = 3e-09
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNGRL CLGS+QHLK++F GY I ++ +S + D+ R + +NF E
Sbjct: 684 CTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKS-SQSVKDVVR---FFNRNFPEAM 739
Query: 689 LVETYLGMSTYHVSS 733
L E + Y + S
Sbjct: 740 LKERHHTKVQYQLKS 754
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 604 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 663
Query: 451 VGGGRT 468
+ GR+
Sbjct: 664 IKTGRS 669
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 670 VVLTSHSMEECEAL 683
>AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), membertor protein.
Length = 2435
Score = 109 bits (261), Expect = 1e-23
Identities = 50/76 (65%), Positives = 59/76 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTF+MLTGD + G+A V+GHSV + V + +GYCPQ DALFD
Sbjct: 2082 CFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDE 2141
Query: 182 LTARETLQIFCLLRGI 229
LTARE LQ++ LRGI
Sbjct: 2142 LTAREHLQLYTRLRGI 2157
Score = 68.9 bits (161), Expect = 2e-11
Identities = 30/74 (40%), Positives = 45/74 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A ++GH +R + ++ + +G CPQ + LFD LT
Sbjct: 1023 LGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVE 1082
Query: 194 ETLQIFCLLRGIPQ 235
E L + L+ + Q
Sbjct: 1083 EHLWFYSRLKSMAQ 1096
Score = 61.7 bits (143), Expect = 3e-09
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNGRL CLGS+QHLK++F GY I ++ +S + D+ R + +NF E
Sbjct: 2252 CTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKS-SQSVKDVVR---FFNRNFPEAM 2307
Query: 689 LVETYLGMSTYHVSS 733
L E + Y + S
Sbjct: 2308 LKERHHTKVQYQLKS 2322
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 2172 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 2231
Query: 451 VGGGRT 468
+ GR+
Sbjct: 2232 IKTGRS 2237
Score = 39.1 bits (87), Expect = 0.017
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
V S G KRK+S LDEPT G+DP ++R +W
Sbjct: 1120 VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIW 1162
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2238 VVLTSHSMEECEAL 2251
>AL807752-20|CAI12766.1| 226|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), membertor protein.
Length = 226
Score = 109 bits (261), Expect = 1e-23
Identities = 50/76 (65%), Positives = 59/76 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTF+MLTGD + G+A V+GHSV + V + +GYCPQ DALFD
Sbjct: 36 CFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDE 95
Query: 182 LTARETLQIFCLLRGI 229
LTARE LQ++ LRGI
Sbjct: 96 LTAREHLQLYTRLRGI 111
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 126 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 185
Query: 451 VGGGRT 468
+ GR+
Sbjct: 186 IKTGRS 191
Score = 39.5 bits (88), Expect = 0.013
Identities = 15/21 (71%), Positives = 19/21 (90%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHL 571
C++L +MVNGRL CLGS+QHL
Sbjct: 206 CTRLAIMVNGRLRCLGSIQHL 226
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 192 VVLTSHSMEECEAL 205
>AL162060-1|CAB82398.1| 373|Homo sapiens hypothetical protein
protein.
Length = 373
Score = 109 bits (261), Expect = 1e-23
Identities = 50/76 (65%), Positives = 59/76 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTF+MLTGD + G+A V+GHSV + V + +GYCPQ DALFD
Sbjct: 20 CFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDE 79
Query: 182 LTARETLQIFCLLRGI 229
LTARE LQ++ LRGI
Sbjct: 80 LTAREHLQLYTRLRGI 95
Score = 61.7 bits (143), Expect = 3e-09
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNGRL CLGS+QHLK++F GY I ++ +S + D+ R + +NF E
Sbjct: 190 CTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKS-SQSVKDVVR---FFNRNFPEAM 245
Query: 689 LVETYLGMSTYHVSS 733
L E + Y + S
Sbjct: 246 LKERHHTKVQYQLKS 260
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 110 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 169
Query: 451 VGGGRT 468
+ GR+
Sbjct: 170 IKTGRS 175
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 176 VVLTSHSMEECEAL 189
>AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2
protein.
Length = 2436
Score = 109 bits (261), Expect = 1e-23
Identities = 50/76 (65%), Positives = 59/76 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTF+MLTGD + G+A V+GHSV + V + +GYCPQ DALFD
Sbjct: 2083 CFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDE 2142
Query: 182 LTARETLQIFCLLRGI 229
LTARE LQ++ LRGI
Sbjct: 2143 LTAREHLQLYTRLRGI 2158
Score = 68.9 bits (161), Expect = 2e-11
Identities = 30/74 (40%), Positives = 45/74 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A ++GH +R + ++ + +G CPQ + LFD LT
Sbjct: 1024 LGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVE 1083
Query: 194 ETLQIFCLLRGIPQ 235
E L + L+ + Q
Sbjct: 1084 EHLWFYSRLKSMAQ 1097
Score = 61.7 bits (143), Expect = 3e-09
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNGRL CLGS+QHLK++F GY I ++ +S + D+ R + +NF E
Sbjct: 2253 CTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKS-SQSVKDVVR---FFNRNFPEAM 2308
Query: 689 LVETYLGMSTYHVSS 733
L E + Y + S
Sbjct: 2309 LKERHHTKVQYQLKS 2323
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 2173 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 2232
Query: 451 VGGGRT 468
+ GR+
Sbjct: 2233 IKTGRS 2238
Score = 39.1 bits (87), Expect = 0.017
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
V S G KRK+S LDEPT G+DP ++R +W
Sbjct: 1121 VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIW 1163
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2239 VVLTSHSMEECEAL 2252
>AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2
protein.
Length = 2436
Score = 109 bits (261), Expect = 1e-23
Identities = 50/76 (65%), Positives = 59/76 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTF+MLTGD + G+A V+GHSV + V + +GYCPQ DALFD
Sbjct: 2083 CFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDE 2142
Query: 182 LTARETLQIFCLLRGI 229
LTARE LQ++ LRGI
Sbjct: 2143 LTAREHLQLYTRLRGI 2158
Score = 68.9 bits (161), Expect = 2e-11
Identities = 30/74 (40%), Positives = 45/74 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A ++GH +R + ++ + +G CPQ + LFD LT
Sbjct: 1024 LGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVE 1083
Query: 194 ETLQIFCLLRGIPQ 235
E L + L+ + Q
Sbjct: 1084 EHLWFYSRLKSMAQ 1097
Score = 61.7 bits (143), Expect = 3e-09
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNGRL CLGS+QHLK++F GY I ++ +S + D+ R + +NF E
Sbjct: 2253 CTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKS-SQSVKDVVR---FFNRNFPEAM 2308
Query: 689 LVETYLGMSTYHVSS 733
L E + Y + S
Sbjct: 2309 LKERHHTKVQYQLKS 2323
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 2173 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 2232
Query: 451 VGGGRT 468
+ GR+
Sbjct: 2233 IKTGRS 2238
Score = 39.1 bits (87), Expect = 0.017
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
V S G KRK+S LDEPT G+DP ++R +W
Sbjct: 1121 VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIW 1163
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2239 VVLTSHSMEECEAL 2252
>AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette
sub-family A member 2 protein.
Length = 2436
Score = 109 bits (261), Expect = 1e-23
Identities = 50/76 (65%), Positives = 59/76 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTF+MLTGD + G+A V+GHSV + V + +GYCPQ DALFD
Sbjct: 2083 CFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDE 2142
Query: 182 LTARETLQIFCLLRGI 229
LTARE LQ++ LRGI
Sbjct: 2143 LTAREHLQLYTRLRGI 2158
Score = 68.9 bits (161), Expect = 2e-11
Identities = 30/74 (40%), Positives = 45/74 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A ++GH +R + ++ + +G CPQ + LFD LT
Sbjct: 1024 LGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVE 1083
Query: 194 ETLQIFCLLRGIPQ 235
E L + L+ + Q
Sbjct: 1084 EHLWFYSRLKSMAQ 1097
Score = 61.7 bits (143), Expect = 3e-09
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNGRL CLGS+QHLK++F GY I ++ +S + D+ R + +NF E
Sbjct: 2253 CTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKS-SQSVKDVVR---FFNRNFPEAM 2308
Query: 689 LVETYLGMSTYHVSS 733
L E + Y + S
Sbjct: 2309 LKERHHTKVQYQLKS 2323
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 2173 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 2232
Query: 451 VGGGRT 468
+ GR+
Sbjct: 2233 IKTGRS 2238
Score = 39.1 bits (87), Expect = 0.017
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
V S G KRK+S LDEPT G+DP ++R +W
Sbjct: 1121 VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIW 1163
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2239 VVLTSHSMEECEAL 2252
>AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein.
Length = 1771
Score = 109 bits (261), Expect = 1e-23
Identities = 50/76 (65%), Positives = 59/76 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTF+MLTGD + G+A V+GHSV + V + +GYCPQ DALFD
Sbjct: 1418 CFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDE 1477
Query: 182 LTARETLQIFCLLRGI 229
LTARE LQ++ LRGI
Sbjct: 1478 LTAREHLQLYTRLRGI 1493
Score = 68.9 bits (161), Expect = 2e-11
Identities = 30/74 (40%), Positives = 45/74 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A ++GH +R + ++ + +G CPQ + LFD LT
Sbjct: 359 LGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVE 418
Query: 194 ETLQIFCLLRGIPQ 235
E L + L+ + Q
Sbjct: 419 EHLWFYSRLKSMAQ 432
Score = 61.7 bits (143), Expect = 3e-09
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNGRL CLGS+QHLK++F GY I ++ +S + D+ R + +NF E
Sbjct: 1588 CTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKS-SQSVKDVVR---FFNRNFPEAM 1643
Query: 689 LVETYLGMSTYHVSS 733
L E + Y + S
Sbjct: 1644 LKERHHTKVQYQLKS 1658
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 1508 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 1567
Query: 451 VGGGRT 468
+ GR+
Sbjct: 1568 IKTGRS 1573
Score = 39.1 bits (87), Expect = 0.017
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
V S G KRK+S LDEPT G+DP ++R +W
Sbjct: 456 VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIW 498
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 1574 VVLTSHSMEECEAL 1587
>X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein.
Length = 1704
Score = 107 bits (257), Expect = 4e-23
Identities = 47/79 (59%), Positives = 60/79 (75%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLG NGAGKT+TF+MLTG+ ++ GDA V GH + + V V + IGYCPQFDAL D+
Sbjct: 1411 CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQRIGYCPQFDALLDH 1470
Query: 182 LTARETLQIFCLLRGIPQR 238
+T RE L ++ LRGIP+R
Sbjct: 1471 MTGREMLVMYARLRGIPER 1489
Score = 74.1 bits (174), Expect = 5e-13
Identities = 41/112 (36%), Positives = 62/112 (55%), Gaps = 5/112 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG + G A + G+ + + + + +G CPQ D LFDNLT
Sbjct: 564 LLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTV 623
Query: 191 RETLQIFCLLRGI-----PQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQK 331
E L + L+G+ P+ V +L I+ L + + + RF+S + +K
Sbjct: 624 AEHLYFYAQLKGLSRQKCPEEVKQMLHIIGL---EDKWNSRSRFLSGGMRRK 672
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MV G+ CLGS QHLKSKF GY++ K +S +++ + ++ F
Sbjct: 1581 CTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLRAKVQSEGQQEA-LEEFKAFVDLTFPGSV 1639
Query: 689 LVETYLGMSTYHVSSAGLPW 748
L + + GM YH+ L W
Sbjct: 1640 LEDEHQGMVHYHLPGRDLSW 1659
Score = 54.8 bits (126), Expect = 3e-07
Identities = 33/97 (34%), Positives = 49/97 (50%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
H +K V S G KRK+ST FLDEP+TGMDP ++RL+W ++ A G+
Sbjct: 1507 HANKLVRTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKA 1566
Query: 469 WC*RHTAWRSARLLLQAHRHGQRQALLSRLAATSQEQ 579
+++ +H + +AL +RLA Q Q
Sbjct: 1567 ------------IIITSHSMEECEALCTRLAIMVQGQ 1591
Score = 37.5 bits (83), Expect = 0.051
Identities = 17/53 (32%), Positives = 26/53 (49%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+G ++ + S G +RK+S LDEPT+GMD S+R +W
Sbjct: 652 IGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIW 704
>U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein.
Length = 1704
Score = 107 bits (257), Expect = 4e-23
Identities = 47/79 (59%), Positives = 60/79 (75%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLG NGAGKT+TF+MLTG+ ++ GDA V GH + + V V + IGYCPQFDAL D+
Sbjct: 1411 CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQRIGYCPQFDALLDH 1470
Query: 182 LTARETLQIFCLLRGIPQR 238
+T RE L ++ LRGIP+R
Sbjct: 1471 MTGREMLVMYARLRGIPER 1489
Score = 74.1 bits (174), Expect = 5e-13
Identities = 41/112 (36%), Positives = 62/112 (55%), Gaps = 5/112 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG + G A + G+ + + + + +G CPQ D LFDNLT
Sbjct: 564 LLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTV 623
Query: 191 RETLQIFCLLRGI-----PQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQK 331
E L + L+G+ P+ V +L I+ L + + + RF+S + +K
Sbjct: 624 AEHLYFYAQLKGLSRQKCPEEVKQMLHIIGL---EDKWNSRSRFLSGGMRRK 672
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MV G+ CLGS QHLKSKF GY++ K +S +++ + ++ F
Sbjct: 1581 CTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLRAKVQSEGQQEA-LEEFKAFVDLTFPGSV 1639
Query: 689 LVETYLGMSTYHVSSAGLPW 748
L + + GM YH+ L W
Sbjct: 1640 LEDEHQGMVHYHLPGRDLSW 1659
Score = 54.8 bits (126), Expect = 3e-07
Identities = 33/97 (34%), Positives = 49/97 (50%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
H +K V S G KRK+ST FLDEP+TGMDP ++RL+W ++ A G+
Sbjct: 1507 HANKLVRTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKA 1566
Query: 469 WC*RHTAWRSARLLLQAHRHGQRQALLSRLAATSQEQ 579
+++ +H + +AL +RLA Q Q
Sbjct: 1567 ------------IIITSHSMEECEALCTRLAIMVQGQ 1591
Score = 37.5 bits (83), Expect = 0.051
Identities = 17/53 (32%), Positives = 26/53 (49%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+G ++ + S G +RK+S LDEPT+GMD S+R +W
Sbjct: 652 IGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIW 704
>DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), member 3 protein.
Length = 1704
Score = 107 bits (257), Expect = 4e-23
Identities = 47/79 (59%), Positives = 60/79 (75%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLG NGAGKT+TF+MLTG+ ++ GDA V GH + + V V + IGYCPQFDAL D+
Sbjct: 1411 CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQRIGYCPQFDALLDH 1470
Query: 182 LTARETLQIFCLLRGIPQR 238
+T RE L ++ LRGIP+R
Sbjct: 1471 MTGREMLVMYARLRGIPER 1489
Score = 74.1 bits (174), Expect = 5e-13
Identities = 41/112 (36%), Positives = 62/112 (55%), Gaps = 5/112 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG + G A + G+ + + + + +G CPQ D LFDNLT
Sbjct: 564 LLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTV 623
Query: 191 RETLQIFCLLRGI-----PQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQK 331
E L + L+G+ P+ V +L I+ L + + + RF+S + +K
Sbjct: 624 AEHLYFYAQLKGLSRQKCPEEVKQMLHIIGL---EDKWNSRSRFLSGGMRRK 672
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MV G+ CLGS QHLKSKF GY++ K +S +++ + ++ F
Sbjct: 1581 CTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLRAKVQSEGQQEA-LEEFKAFVDLTFPGSV 1639
Query: 689 LVETYLGMSTYHVSSAGLPW 748
L + + GM YH+ L W
Sbjct: 1640 LEDEHQGMVHYHLPGRDLSW 1659
Score = 54.8 bits (126), Expect = 3e-07
Identities = 33/97 (34%), Positives = 49/97 (50%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
H +K V S G KRK+ST FLDEP+TGMDP ++RL+W ++ A G+
Sbjct: 1507 HANKLVRTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKA 1566
Query: 469 WC*RHTAWRSARLLLQAHRHGQRQALLSRLAATSQEQ 579
+++ +H + +AL +RLA Q Q
Sbjct: 1567 ------------IIITSHSMEECEALCTRLAIMVQGQ 1591
Score = 37.5 bits (83), Expect = 0.051
Identities = 17/53 (32%), Positives = 26/53 (49%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+G ++ + S G +RK+S LDEPT+GMD S+R +W
Sbjct: 652 IGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIW 704
>AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein
protein.
Length = 1708
Score = 107 bits (257), Expect = 4e-23
Identities = 47/79 (59%), Positives = 60/79 (75%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLG NGAGKT+TF+MLTG+ ++ GDA V GH + + V V + IGYCPQFDAL D+
Sbjct: 1415 CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQRIGYCPQFDALLDH 1474
Query: 182 LTARETLQIFCLLRGIPQR 238
+T RE L ++ LRGIP+R
Sbjct: 1475 MTGREMLVMYARLRGIPER 1493
Score = 74.1 bits (174), Expect = 5e-13
Identities = 41/112 (36%), Positives = 62/112 (55%), Gaps = 5/112 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG + G A + G+ + + + + +G CPQ D LFDNLT
Sbjct: 568 LLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTV 627
Query: 191 RETLQIFCLLRGI-----PQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQK 331
E L + L+G+ P+ V +L I+ L + + + RF+S + +K
Sbjct: 628 AEHLYFYAQLKGLSRQKCPEEVKQMLHIIGL---EDKWNSRSRFLSGGMRRK 676
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MV G+ CLGS QHLKSKF GY++ K +S +++ + ++ F
Sbjct: 1585 CTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLRAKVQSEGQQEA-LEEFKAFVDLTFPGSV 1643
Query: 689 LVETYLGMSTYHVSSAGLPW 748
L + + GM YH+ L W
Sbjct: 1644 LEDEHQGMVHYHLPGRDLSW 1663
Score = 54.8 bits (126), Expect = 3e-07
Identities = 33/97 (34%), Positives = 49/97 (50%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
H +K V S G KRK+ST FLDEP+TGMDP ++RL+W ++ A G+
Sbjct: 1511 HANKLVRTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKA 1570
Query: 469 WC*RHTAWRSARLLLQAHRHGQRQALLSRLAATSQEQ 579
+++ +H + +AL +RLA Q Q
Sbjct: 1571 ------------IIITSHSMEECEALCTRLAIMVQGQ 1595
Score = 37.5 bits (83), Expect = 0.051
Identities = 17/53 (32%), Positives = 26/53 (49%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+G ++ + S G +RK+S LDEPT+GMD S+R +W
Sbjct: 656 IGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIW 708
>AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane
specific ATP-binding cassette protein protein.
Length = 1704
Score = 107 bits (257), Expect = 4e-23
Identities = 47/79 (59%), Positives = 60/79 (75%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLG NGAGKT+TF+MLTG+ ++ GDA V GH + + V V + IGYCPQFDAL D+
Sbjct: 1411 CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVGGHRISSDVGKVRQRIGYCPQFDALLDH 1470
Query: 182 LTARETLQIFCLLRGIPQR 238
+T RE L ++ LRGIP+R
Sbjct: 1471 MTGREMLVMYARLRGIPER 1489
Score = 74.1 bits (174), Expect = 5e-13
Identities = 41/112 (36%), Positives = 62/112 (55%), Gaps = 5/112 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG + G A + G+ + + + + +G CPQ D LFDNLT
Sbjct: 564 LLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTV 623
Query: 191 RETLQIFCLLRGI-----PQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQK 331
E L + L+G+ P+ V +L I+ L + + + RF+S + +K
Sbjct: 624 AEHLYFYAQLKGLSRQKCPEEVKQMLHIIGL---EDKWNSRSRFLSGGMRRK 672
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MV G+ CLGS QHLKSKF GY++ K +S +++ + ++ F
Sbjct: 1581 CTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLRAKVQSEGQQEA-LEEFKAFVDLTFPGSV 1639
Query: 689 LVETYLGMSTYHVSSAGLPW 748
L + + GM YH+ L W
Sbjct: 1640 LEDEHQGMVHYHLPGRDLSW 1659
Score = 54.8 bits (126), Expect = 3e-07
Identities = 33/97 (34%), Positives = 49/97 (50%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
H +K V S G KRK+ST FLDEP+TGMDP ++RL+W ++ A G+
Sbjct: 1507 HANKLVRTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKA 1566
Query: 469 WC*RHTAWRSARLLLQAHRHGQRQALLSRLAATSQEQ 579
+++ +H + +AL +RLA Q Q
Sbjct: 1567 ------------IIITSHSMEECEALCTRLAIMVQGQ 1591
Score = 37.5 bits (83), Expect = 0.051
Identities = 17/53 (32%), Positives = 26/53 (49%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+G ++ + S G +RK+S LDEPT+GMD S+R +W
Sbjct: 652 IGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIW 704
>Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein.
Length = 2273
Score = 106 bits (255), Expect = 7e-23
Identities = 46/77 (59%), Positives = 60/77 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKT+TF+MLTGD V+ GDA V G S+ ++ +VH+ +GYCPQFDA+ +
Sbjct: 1967 CFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL 2026
Query: 182 LTARETLQIFCLLRGIP 232
LT RE L ++ LRG+P
Sbjct: 2027 LTGREHLYLYARLRGVP 2043
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS-GTDRDSDITRIDQYMKKNFNEV 685
C++L +MV G C+G++QHLKSKF GY + +K +S D D+ ++Q+ + NF
Sbjct: 2137 CTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQGNFPGS 2196
Query: 686 KLVETYLGMSTYHVSSAGL 742
E + M + VSS+ L
Sbjct: 2197 VQRERHYNMLQFQVSSSSL 2215
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/74 (39%), Positives = 41/74 (55%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G LV G + + V + +G CPQ + LF +LT
Sbjct: 962 LGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFHHLTVA 1021
Query: 194 ETLQIFCLLRGIPQ 235
E + + L+G Q
Sbjct: 1022 EHMLFYAQLKGKSQ 1035
Score = 54.0 bits (124), Expect = 6e-07
Identities = 27/64 (42%), Positives = 34/64 (53%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG V+ D S G KRK+ST LDEPTTGMDP ++R++W I S +
Sbjct: 2058 LGLTVYADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSII 2117
Query: 454 GGGR 465
GR
Sbjct: 2118 REGR 2121
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = +1
Query: 295 DKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+++ + S G +RK+S LDEPT+G+DP S+R +W
Sbjct: 1056 NEEAQDLSGGMQRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIW 1101
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2123 VVLTSHSMEECEAL 2136
>U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette
transporter protein.
Length = 2273
Score = 106 bits (255), Expect = 7e-23
Identities = 46/77 (59%), Positives = 60/77 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKT+TF+MLTGD V+ GDA V G S+ ++ +VH+ +GYCPQFDA+ +
Sbjct: 1967 CFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL 2026
Query: 182 LTARETLQIFCLLRGIP 232
LT RE L ++ LRG+P
Sbjct: 2027 LTGREHLYLYARLRGVP 2043
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS-GTDRDSDITRIDQYMKKNFNEV 685
C++L +MV G C+G++QHLKSKF GY + +K +S D D+ ++Q+ + NF
Sbjct: 2137 CTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQGNFPGS 2196
Query: 686 KLVETYLGMSTYHVSSAGL 742
E + M + VSS+ L
Sbjct: 2197 VQRERHYNMLQFQVSSSSL 2215
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/74 (39%), Positives = 41/74 (55%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G LV G + + V + +G CPQ + LF +LT
Sbjct: 962 LGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFHHLTVA 1021
Query: 194 ETLQIFCLLRGIPQ 235
E + + L+G Q
Sbjct: 1022 EHMLFYAQLKGKSQ 1035
Score = 54.0 bits (124), Expect = 6e-07
Identities = 27/64 (42%), Positives = 34/64 (53%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG V+ D S G KRK+ST LDEPTTGMDP ++R++W I S +
Sbjct: 2058 LGLTVYADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSII 2117
Query: 454 GGGR 465
GR
Sbjct: 2118 RKGR 2121
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = +1
Query: 295 DKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+++ + S G +RK+S LDEPT+G+DP S+R +W
Sbjct: 1056 NEEAQDLSGGMQRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIW 1101
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2123 VVLTSHSMEECEAL 2136
>AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter protein.
Length = 2273
Score = 106 bits (255), Expect = 7e-23
Identities = 46/77 (59%), Positives = 60/77 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKT+TF+MLTGD V+ GDA V G S+ ++ +VH+ +GYCPQFDA+ +
Sbjct: 1967 CFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL 2026
Query: 182 LTARETLQIFCLLRGIP 232
LT RE L ++ LRG+P
Sbjct: 2027 LTGREHLYLYARLRGVP 2043
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS-GTDRDSDITRIDQYMKKNFNEV 685
C++L +MV G C+G++QHLKSKF GY + +K +S D D+ ++Q+ + NF
Sbjct: 2137 CTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQGNFPGS 2196
Query: 686 KLVETYLGMSTYHVSSAGL 742
E + M + VSS+ L
Sbjct: 2197 VQRERHYNMLQFQVSSSSL 2215
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/74 (39%), Positives = 41/74 (55%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G LV G + + V + +G CPQ + LF +LT
Sbjct: 962 LGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFHHLTVA 1021
Query: 194 ETLQIFCLLRGIPQ 235
E + + L+G Q
Sbjct: 1022 EHMLFYAQLKGKSQ 1035
Score = 54.0 bits (124), Expect = 6e-07
Identities = 27/64 (42%), Positives = 34/64 (53%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG V+ D S G KRK+ST LDEPTTGMDP ++R++W I S +
Sbjct: 2058 LGLTVYADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSII 2117
Query: 454 GGGR 465
GR
Sbjct: 2118 REGR 2121
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = +1
Query: 295 DKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+++ + S G +RK+S LDEPT+G+DP S+R +W
Sbjct: 1056 NEEAQDLSGGMQRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIW 1101
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2123 VVLTSHSMEECEAL 2136
>AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein
protein.
Length = 2303
Score = 106 bits (255), Expect = 7e-23
Identities = 46/77 (59%), Positives = 60/77 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKT+TF+MLTGD V+ GDA V G S+ ++ +VH+ +GYCPQFDA+ +
Sbjct: 1997 CFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL 2056
Query: 182 LTARETLQIFCLLRGIP 232
LT RE L ++ LRG+P
Sbjct: 2057 LTGREHLYLYARLRGVP 2073
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS-GTDRDSDITRIDQYMKKNFNEV 685
C++L +MV G C+G++QHLKSKF GY + +K +S D D+ ++Q+ + NF
Sbjct: 2167 CTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQGNFPGS 2226
Query: 686 KLVETYLGMSTYHVSSAGL 742
E + M + VSS+ L
Sbjct: 2227 VQRERHYNMLQFQVSSSSL 2245
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/74 (39%), Positives = 41/74 (55%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G LV G + + V + +G CPQ + LF +LT
Sbjct: 992 LGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFHHLTVA 1051
Query: 194 ETLQIFCLLRGIPQ 235
E + + L+G Q
Sbjct: 1052 EHMLFYAQLKGKSQ 1065
Score = 54.0 bits (124), Expect = 6e-07
Identities = 27/64 (42%), Positives = 34/64 (53%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG V+ D S G KRK+ST LDEPTTGMDP ++R++W I S +
Sbjct: 2088 LGLTVYADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSII 2147
Query: 454 GGGR 465
GR
Sbjct: 2148 REGR 2151
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = +1
Query: 295 DKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+++ + S G +RK+S LDEPT+G+DP S+R +W
Sbjct: 1086 NEEAQDLSGGMQRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIW 1131
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2153 VVLTSHSMEECEAL 2166
>AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette
transporter protein.
Length = 2273
Score = 105 bits (253), Expect = 1e-22
Identities = 46/77 (59%), Positives = 60/77 (77%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKT+TF+MLTGD V+ GDA V G S+ ++ +VH+ +GYCPQFDA+ +
Sbjct: 1967 CFGLLGVNGAGKTTTFKMLTGDNTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL 2026
Query: 182 LTARETLQIFCLLRGIP 232
LT RE L ++ LRG+P
Sbjct: 2027 LTGREHLYLYARLRGVP 2043
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS-GTDRDSDITRIDQYMKKNFNEV 685
C++L +MV G C+G++QHLKSKF GY + +K +S D D+ ++Q+ + NF
Sbjct: 2137 CTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQGNFPGS 2196
Query: 686 KLVETYLGMSTYHVSSAGL 742
E + M + VSS+ L
Sbjct: 2197 VQRERHYNMLQFQVSSSSL 2215
Score = 58.4 bits (135), Expect = 3e-08
Identities = 29/74 (39%), Positives = 41/74 (55%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G LV G + + V + +G CPQ + LF +LT
Sbjct: 962 LGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHNILFHHLTVA 1021
Query: 194 ETLQIFCLLRGIPQ 235
E + + L+G Q
Sbjct: 1022 EHMLFYAQLKGKSQ 1035
Score = 54.0 bits (124), Expect = 6e-07
Identities = 27/64 (42%), Positives = 34/64 (53%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG V+ D S G KRK+ST LDEPTTGMDP ++R++W I S +
Sbjct: 2058 LGLTVYADCLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSII 2117
Query: 454 GGGR 465
GR
Sbjct: 2118 REGR 2121
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = +1
Query: 295 DKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
+++ + S G +RK+S LDEPT+G+DP S+R +W
Sbjct: 1056 NEEAQDLSGGMQRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIW 1101
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 2123 VVLTSHSMEECEAL 2136
>AL137481-1|CAB70762.1| 269|Homo sapiens hypothetical protein
protein.
Length = 269
Score = 103 bits (246), Expect = 9e-22
Identities = 46/78 (58%), Positives = 57/78 (73%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTFRM+TGD S G+A++ GHSV H +GYCPQ DA+F+
Sbjct: 103 CFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFEL 162
Query: 182 LTARETLQIFCLLRGIPQ 235
LT RE L++ LRG+P+
Sbjct: 163 LTGREHLELLARLRGVPE 180
Score = 54.4 bits (125), Expect = 4e-07
Identities = 25/65 (38%), Positives = 36/65 (55%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG + D+ S G KRK++T FLDEPTTGMDP+++R +W + + V
Sbjct: 194 LGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVV 253
Query: 454 GGGRT 468
GR+
Sbjct: 254 REGRS 258
>AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member 7
protein.
Length = 2146
Score = 103 bits (246), Expect = 9e-22
Identities = 46/78 (58%), Positives = 57/78 (73%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTFRM+TGD S G+A++ GHSV H +GYCPQ DA+F+
Sbjct: 1822 CFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFEL 1881
Query: 182 LTARETLQIFCLLRGIPQ 235
LT RE L++ LRG+P+
Sbjct: 1882 LTGREHLELLARLRGVPE 1899
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/76 (40%), Positives = 45/76 (59%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +L+G S G A + GH VR+ + + +G CPQ++ LFD LT
Sbjct: 840 LGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVD 899
Query: 194 ETLQIFCLLRGIPQRV 241
E + + L+G+ V
Sbjct: 900 EHVWFYGRLKGLSAAV 915
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 49/96 (51%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG + D+ S G KRK++T FLDEPTTGMDP+++R +W + + V
Sbjct: 1913 LGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVV 1972
Query: 454 GGGRTWC*RHTAWRSARLLLQAHRHGQRQALLSRLA 561
GR+ ++L +H + +AL SRLA
Sbjct: 1973 REGRS------------VMLTSHSMEECEALCSRLA 1996
Score = 50.0 bits (114), Expect = 9e-06
Identities = 19/34 (55%), Positives = 27/34 (79%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIK 610
CS+L +MVNGR CLGS QHLK +F+ G+T+ ++
Sbjct: 1992 CSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLR 2025
Score = 44.4 bits (100), Expect = 4e-04
Identities = 21/58 (36%), Positives = 29/58 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
RL ++G V + S G +RK+S LDEPT G+DPAS+R +W
Sbjct: 922 RLLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIW 979
>AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7
protein.
Length = 2146
Score = 103 bits (246), Expect = 9e-22
Identities = 46/78 (58%), Positives = 57/78 (73%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTFRM+TGD S G+A++ GHSV H +GYCPQ DA+F+
Sbjct: 1822 CFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFEL 1881
Query: 182 LTARETLQIFCLLRGIPQ 235
LT RE L++ LRG+P+
Sbjct: 1882 LTGREHLELLARLRGVPE 1899
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/76 (40%), Positives = 45/76 (59%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +L+G S G A + GH VR+ + + +G CPQ++ LFD LT
Sbjct: 840 LGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVD 899
Query: 194 ETLQIFCLLRGIPQRV 241
E + + L+G+ V
Sbjct: 900 EHVWFYGRLKGLSAAV 915
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 49/96 (51%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG + D+ S G KRK++T FLDEPTTGMDP+++R +W + + V
Sbjct: 1913 LGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVV 1972
Query: 454 GGGRTWC*RHTAWRSARLLLQAHRHGQRQALLSRLA 561
GR+ ++L +H + +AL SRLA
Sbjct: 1973 REGRS------------VMLTSHSMEECEALCSRLA 1996
Score = 50.0 bits (114), Expect = 9e-06
Identities = 19/34 (55%), Positives = 27/34 (79%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIK 610
CS+L +MVNGR CLGS QHLK +F+ G+T+ ++
Sbjct: 1992 CSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLR 2025
Score = 44.4 bits (100), Expect = 4e-04
Identities = 21/58 (36%), Positives = 29/58 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
RL ++G V + S G +RK+S LDEPT G+DPAS+R +W
Sbjct: 922 RLLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIW 979
>AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transporter
protein.
Length = 2146
Score = 103 bits (246), Expect = 9e-22
Identities = 46/78 (58%), Positives = 57/78 (73%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTFRM+TGD S G+A++ GHSV H +GYCPQ DA+F+
Sbjct: 1822 CFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFEL 1881
Query: 182 LTARETLQIFCLLRGIPQ 235
LT RE L++ LRG+P+
Sbjct: 1882 LTGREHLELLARLRGVPE 1899
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/76 (40%), Positives = 45/76 (59%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +L+G S G A + GH VR+ + + +G CPQ++ LFD LT
Sbjct: 840 LGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVD 899
Query: 194 ETLQIFCLLRGIPQRV 241
E + + L+G+ V
Sbjct: 900 EHVWFYGRLKGLSAAV 915
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 49/96 (51%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG + D+ S G KRK++T FLDEPTTGMDP+++R +W + + V
Sbjct: 1913 LGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVV 1972
Query: 454 GGGRTWC*RHTAWRSARLLLQAHRHGQRQALLSRLA 561
GR+ ++L +H + +AL SRLA
Sbjct: 1973 REGRS------------VMLTSHSMEECEALCSRLA 1996
Score = 50.0 bits (114), Expect = 9e-06
Identities = 19/34 (55%), Positives = 27/34 (79%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIK 610
CS+L +MVNGR CLGS QHLK +F+ G+T+ ++
Sbjct: 1992 CSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLR 2025
Score = 44.4 bits (100), Expect = 4e-04
Identities = 21/58 (36%), Positives = 29/58 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
RL ++G V + S G +RK+S LDEPT G+DPAS+R +W
Sbjct: 922 RLLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIW 979
>AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein.
Length = 2008
Score = 103 bits (246), Expect = 9e-22
Identities = 46/78 (58%), Positives = 57/78 (73%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
CFGLLGVNGAGKTSTFRM+TGD S G+A++ GHSV H +GYCPQ DA+F+
Sbjct: 1684 CFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFEL 1743
Query: 182 LTARETLQIFCLLRGIPQ 235
LT RE L++ LRG+P+
Sbjct: 1744 LTGREHLELLARLRGVPE 1761
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/76 (40%), Positives = 45/76 (59%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +L+G S G A + GH VR+ + + +G CPQ++ LFD LT
Sbjct: 702 LGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVD 761
Query: 194 ETLQIFCLLRGIPQRV 241
E + + L+G+ V
Sbjct: 762 EHVWFYGRLKGLSAAV 777
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 49/96 (51%)
Frame = +1
Query: 274 LGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
LG + D+ S G KRK++T FLDEPTTGMDP+++R +W + + V
Sbjct: 1775 LGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVV 1834
Query: 454 GGGRTWC*RHTAWRSARLLLQAHRHGQRQALLSRLA 561
GR+ ++L +H + +AL SRLA
Sbjct: 1835 REGRS------------VMLTSHSMEECEALCSRLA 1858
Score = 50.0 bits (114), Expect = 9e-06
Identities = 19/34 (55%), Positives = 27/34 (79%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIK 610
CS+L +MVNGR CLGS QHLK +F+ G+T+ ++
Sbjct: 1854 CSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLR 1887
Score = 44.4 bits (100), Expect = 4e-04
Identities = 21/58 (36%), Positives = 29/58 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
RL ++G V + S G +RK+S LDEPT G+DPAS+R +W
Sbjct: 784 RLLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIW 841
>AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subfamily
A protein.
Length = 2595
Score = 82.6 bits (195), Expect = 1e-15
Identities = 40/80 (50%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHS-VRAHVQDVHRLIGYCPQFDALFD 178
CFGLLGVNGAGKT+ F+MLTGD S G+ L+ + HV L+GYCPQ DAL D
Sbjct: 2285 CFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDD 2344
Query: 179 NLTARETLQIFCLLRGIPQR 238
+T E L + + GIP++
Sbjct: 2345 LVTVEEHLYFYARVHGIPEK 2364
Score = 61.3 bits (142), Expect = 4e-09
Identities = 26/73 (35%), Positives = 47/73 (64%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNG+ C+GSLQH+KS+F +G+T+ + ++ +T+ +M+ +F +
Sbjct: 2456 CTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNKVTMETLTK---FMQLHFPKTY 2512
Query: 689 LVETYLGMSTYHV 727
L + +L M YHV
Sbjct: 2513 LKDQHLSMLEYHV 2525
Score = 59.3 bits (137), Expect = 1e-08
Identities = 29/67 (43%), Positives = 39/67 (58%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG S G V+G ++ + V + +G C Q D LF LT
Sbjct: 1376 LLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTT 1435
Query: 191 RETLQIF 211
+E L ++
Sbjct: 1436 KEHLLLY 1442
Score = 57.2 bits (132), Expect = 6e-08
Identities = 29/68 (42%), Positives = 37/68 (54%)
Frame = +1
Query: 250 TCHRLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLV 429
T H+L L + D+ CS GTKRK+ST LDEP++GMDP SKR +
Sbjct: 2369 TVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2428
Query: 430 WRGISSAV 453
W+ IS V
Sbjct: 2429 WKIISEEV 2436
Score = 48.0 bits (109), Expect = 4e-05
Identities = 24/62 (38%), Positives = 31/62 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R + G H K+V S G KRK+S LDEP+TG+DP S+R +W
Sbjct: 1461 RTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDV 1520
Query: 439 IS 444
IS
Sbjct: 1521 IS 1522
Score = 32.3 bits (70), Expect = 1.9
Identities = 13/17 (76%), Positives = 15/17 (88%)
Frame = +3
Query: 459 RAHVVLTSHSMEECEAL 509
+ V+LTSHSMEECEAL
Sbjct: 2439 KCSVILTSHSMEECEAL 2455
>AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette
transporter family A member 12 protein.
Length = 2277
Score = 82.6 bits (195), Expect = 1e-15
Identities = 40/80 (50%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHS-VRAHVQDVHRLIGYCPQFDALFD 178
CFGLLGVNGAGKT+ F+MLTGD S G+ L+ + HV L+GYCPQ DAL D
Sbjct: 1967 CFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDD 2026
Query: 179 NLTARETLQIFCLLRGIPQR 238
+T E L + + GIP++
Sbjct: 2027 LVTVEEHLYFYARVHGIPEK 2046
Score = 61.3 bits (142), Expect = 4e-09
Identities = 26/73 (35%), Positives = 47/73 (64%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNG+ C+GSLQH+KS+F +G+T+ + ++ +T+ +M+ +F +
Sbjct: 2138 CTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNKVTMETLTK---FMQLHFPKTY 2194
Query: 689 LVETYLGMSTYHV 727
L + +L M YHV
Sbjct: 2195 LKDQHLSMLEYHV 2207
Score = 59.3 bits (137), Expect = 1e-08
Identities = 29/67 (43%), Positives = 39/67 (58%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG S G V+G ++ + V + +G C Q D LF LT
Sbjct: 1058 LLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTT 1117
Query: 191 RETLQIF 211
+E L ++
Sbjct: 1118 KEHLLLY 1124
Score = 57.2 bits (132), Expect = 6e-08
Identities = 29/68 (42%), Positives = 37/68 (54%)
Frame = +1
Query: 250 TCHRLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLV 429
T H+L L + D+ CS GTKRK+ST LDEP++GMDP SKR +
Sbjct: 2051 TVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2110
Query: 430 WRGISSAV 453
W+ IS V
Sbjct: 2111 WKIISEEV 2118
Score = 48.0 bits (109), Expect = 4e-05
Identities = 24/62 (38%), Positives = 31/62 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R + G H K+V S G KRK+S LDEP+TG+DP S+R +W
Sbjct: 1143 RTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDV 1202
Query: 439 IS 444
IS
Sbjct: 1203 IS 1204
Score = 32.3 bits (70), Expect = 1.9
Identities = 13/17 (76%), Positives = 15/17 (88%)
Frame = +3
Query: 459 RAHVVLTSHSMEECEAL 509
+ V+LTSHSMEECEAL
Sbjct: 2121 KCSVILTSHSMEECEAL 2137
>AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette
transporter family A member 12 protein.
Length = 2347
Score = 82.6 bits (195), Expect = 1e-15
Identities = 40/80 (50%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHS-VRAHVQDVHRLIGYCPQFDALFD 178
CFGLLGVNGAGKT+ F+MLTGD S G+ L+ + HV L+GYCPQ DAL D
Sbjct: 2037 CFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDD 2096
Query: 179 NLTARETLQIFCLLRGIPQR 238
+T E L + + GIP++
Sbjct: 2097 LVTVEEHLYFYARVHGIPEK 2116
Score = 61.3 bits (142), Expect = 4e-09
Identities = 26/73 (35%), Positives = 47/73 (64%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNG+ C+GSLQH+KS+F +G+T+ + ++ +T+ +M+ +F +
Sbjct: 2208 CTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNKVTMETLTK---FMQLHFPKTY 2264
Query: 689 LVETYLGMSTYHV 727
L + +L M YHV
Sbjct: 2265 LKDQHLSMLEYHV 2277
Score = 59.3 bits (137), Expect = 1e-08
Identities = 29/67 (43%), Positives = 39/67 (58%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG S G V+G ++ + V + +G C Q D LF LT
Sbjct: 1128 LLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTT 1187
Query: 191 RETLQIF 211
+E L ++
Sbjct: 1188 KEHLLLY 1194
Score = 57.2 bits (132), Expect = 6e-08
Identities = 29/68 (42%), Positives = 37/68 (54%)
Frame = +1
Query: 250 TCHRLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLV 429
T H+L L + D+ CS GTKRK+ST LDEP++GMDP SKR +
Sbjct: 2121 TVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHL 2180
Query: 430 WRGISSAV 453
W+ IS V
Sbjct: 2181 WKIISEEV 2188
Score = 48.0 bits (109), Expect = 4e-05
Identities = 24/62 (38%), Positives = 31/62 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R + G H K+V S G KRK+S LDEP+TG+DP S+R +W
Sbjct: 1213 RTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDV 1272
Query: 439 IS 444
IS
Sbjct: 1273 IS 1274
Score = 32.3 bits (70), Expect = 1.9
Identities = 13/17 (76%), Positives = 15/17 (88%)
Frame = +3
Query: 459 RAHVVLTSHSMEECEAL 509
+ V+LTSHSMEECEAL
Sbjct: 2191 KCSVILTSHSMEECEAL 2207
>AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein.
Length = 2413
Score = 82.6 bits (195), Expect = 1e-15
Identities = 40/80 (50%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHS-VRAHVQDVHRLIGYCPQFDALFD 178
CFGLLGVNGAGKT+ F+MLTGD S G+ L+ + HV L+GYCPQ DAL D
Sbjct: 2285 CFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALDD 2344
Query: 179 NLTARETLQIFCLLRGIPQR 238
+T E L + + GIP++
Sbjct: 2345 LVTVEEHLYFYARVHGIPEK 2364
Score = 59.3 bits (137), Expect = 1e-08
Identities = 29/67 (43%), Positives = 39/67 (58%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+T MLTG S G V+G ++ + V + +G C Q D LF LT
Sbjct: 1376 LLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHDVLFSYLTT 1435
Query: 191 RETLQIF 211
+E L ++
Sbjct: 1436 KEHLLLY 1442
Score = 48.0 bits (109), Expect = 4e-05
Identities = 24/62 (38%), Positives = 31/62 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R + G H K+V S G KRK+S LDEP+TG+DP S+R +W
Sbjct: 1461 RTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDV 1520
Query: 439 IS 444
IS
Sbjct: 1521 IS 1522
>AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein.
Length = 5058
Score = 78.6 bits (185), Expect = 2e-14
Identities = 41/83 (49%), Positives = 55/83 (66%), Gaps = 4/83 (4%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVH---GHSV-RAHVQDVHRLIGYCPQFDA 169
CFGLLGVNGAGK++TF+ML G+ ++ G A++ G +V + LIGYCPQ DA
Sbjct: 4749 CFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQDA 4808
Query: 170 LFDNLTARETLQIFCLLRGIPQR 238
L + LT E L +C LRGIP++
Sbjct: 4809 LDELLTGWEHLYYYCSLRGIPRQ 4831
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/75 (42%), Positives = 45/75 (60%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+ MLTG + G +++G +++ + V +G CPQ D L DNLT
Sbjct: 3873 LLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTV 3932
Query: 191 RETLQIFCLLRGIPQ 235
RE L +F ++ PQ
Sbjct: 3933 REHLLLFASIKA-PQ 3946
Score = 54.4 bits (125), Expect = 4e-07
Identities = 27/58 (46%), Positives = 32/58 (55%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGG 462
H DK V S GTKRK+ST LDEP++GMDP SKR +W+ I V G
Sbjct: 4849 HADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREG 4906
Score = 52.0 bits (119), Expect = 2e-06
Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTI-VIKCRSGTDRDSDITRIDQYMKKNFNEV 685
C++L +MVNG CLGS QH+K++F GYT+ V C+ + ++K F +
Sbjct: 4923 CTRLAIMVNGSFKCLGSPQHIKNRFGDGYTVKVWLCKEANQH----CTVSDHLKLYFPGI 4978
Query: 686 KLVETYLGMSTYHV 727
+ +L + YHV
Sbjct: 4979 QFKGQHLNLLEYHV 4992
Score = 40.7 bits (91), Expect = 0.006
Identities = 18/48 (37%), Positives = 24/48 (50%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
H K+ S G KRK+S LDEPT+G+DP S+ +W
Sbjct: 3968 HQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLW 4015
Score = 30.7 bits (66), Expect = 5.9
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 471 VLTSHSMEECEAL 509
VLTSHSMEECEAL
Sbjct: 4910 VLTSHSMEECEAL 4922
>AK131360-1|BAD18512.1| 1186|Homo sapiens mRNA. protein.
Length = 1186
Score = 78.6 bits (185), Expect = 2e-14
Identities = 41/83 (49%), Positives = 55/83 (66%), Gaps = 4/83 (4%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVH---GHSV-RAHVQDVHRLIGYCPQFDA 169
CFGLLGVNGAGK++TF+ML G+ ++ G A++ G +V + LIGYCPQ DA
Sbjct: 1009 CFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQDA 1068
Query: 170 LFDNLTARETLQIFCLLRGIPQR 238
L + LT E L +C LRGIP++
Sbjct: 1069 LDELLTGWEHLYYYCSLRGIPRQ 1091
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/75 (42%), Positives = 45/75 (60%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+ MLTG + G +++G +++ + V +G CPQ D L DNLT
Sbjct: 133 LLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTV 192
Query: 191 RETLQIFCLLRGIPQ 235
RE L +F ++ PQ
Sbjct: 193 REHLLLFASIKA-PQ 206
Score = 54.4 bits (125), Expect = 4e-07
Identities = 27/58 (46%), Positives = 32/58 (55%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGG 462
H DK V S GTKRK+ST LDEP++GMDP SKR +W+ I V G
Sbjct: 1109 HADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREG 1166
Score = 40.7 bits (91), Expect = 0.006
Identities = 18/48 (37%), Positives = 24/48 (50%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
H K+ S G KRK+S LDEPT+G+DP S+ +W
Sbjct: 228 HQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLW 275
>AK128516-1|BAC87475.1| 788|Homo sapiens protein ( Homo sapiens
cDNA FLJ46673 fis, clone TRACH3009061, weakly similar
to ATP-binding cassette, sub-family A, member 1. ).
Length = 788
Score = 78.6 bits (185), Expect = 2e-14
Identities = 41/83 (49%), Positives = 55/83 (66%), Gaps = 4/83 (4%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVH---GHSV-RAHVQDVHRLIGYCPQFDA 169
CFGLLGVNGAGK++TF+ML G+ ++ G A++ G +V + LIGYCPQ DA
Sbjct: 479 CFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQDA 538
Query: 170 LFDNLTARETLQIFCLLRGIPQR 238
L + LT E L +C LRGIP++
Sbjct: 539 LDELLTGWEHLYYYCSLRGIPRQ 561
Score = 54.4 bits (125), Expect = 4e-07
Identities = 27/58 (46%), Positives = 32/58 (55%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGG 462
H DK V S GTKRK+ST LDEP++GMDP SKR +W+ I V G
Sbjct: 579 HADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREG 636
Score = 52.0 bits (119), Expect = 2e-06
Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTI-VIKCRSGTDRDSDITRIDQYMKKNFNEV 685
C++L +MVNG CLGS QH+K++F GYT+ V C+ + ++K F +
Sbjct: 653 CTRLAIMVNGSFKCLGSPQHIKNRFGDGYTVKVWLCKEANQH----CTVSDHLKLYFPGI 708
Query: 686 KLVETYLGMSTYHV 727
+ +L + YHV
Sbjct: 709 QFKGQHLNLLEYHV 722
Score = 30.7 bits (66), Expect = 5.9
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 471 VLTSHSMEECEAL 509
VLTSHSMEECEAL
Sbjct: 640 VLTSHSMEECEAL 652
>AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette
transporter A13 protein.
Length = 2127
Score = 78.6 bits (185), Expect = 2e-14
Identities = 41/83 (49%), Positives = 55/83 (66%), Gaps = 4/83 (4%)
Frame = +2
Query: 2 CFGLLGVNGAGKTSTFRMLTGDARVSDGDALVH---GHSV-RAHVQDVHRLIGYCPQFDA 169
CFGLLGVNGAGK++TF+ML G+ ++ G A++ G +V + LIGYCPQ DA
Sbjct: 1818 CFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQDA 1877
Query: 170 LFDNLTARETLQIFCLLRGIPQR 238
L + LT E L +C LRGIP++
Sbjct: 1878 LDELLTGWEHLYYYCSLRGIPRQ 1900
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/75 (42%), Positives = 45/75 (60%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+ MLTG + G +++G +++ + V +G CPQ D L DNLT
Sbjct: 941 LLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTV 1000
Query: 191 RETLQIFCLLRGIPQ 235
RE L +F ++ PQ
Sbjct: 1001 REHLLLFASIKA-PQ 1014
Score = 54.4 bits (125), Expect = 4e-07
Identities = 27/58 (46%), Positives = 32/58 (55%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGG 462
H DK V S GTKRK+ST LDEP++GMDP SKR +W+ I V G
Sbjct: 1918 HADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREG 1975
Score = 52.0 bits (119), Expect = 2e-06
Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTI-VIKCRSGTDRDSDITRIDQYMKKNFNEV 685
C++L +MVNG CLGS QH+K++F GYT+ V C+ + ++K F +
Sbjct: 1992 CTRLAIMVNGSFKCLGSPQHIKNRFGDGYTVKVWLCKEANQH----CTVSDHLKLYFPGI 2047
Query: 686 KLVETYLGMSTYHV 727
+ +L + YHV
Sbjct: 2048 QFKGQHLNLLEYHV 2061
Score = 40.7 bits (91), Expect = 0.006
Identities = 18/48 (37%), Positives = 24/48 (50%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
H K+ S G KRK+S LDEPT+G+DP S+ +W
Sbjct: 1036 HQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLW 1083
Score = 30.7 bits (66), Expect = 5.9
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 471 VLTSHSMEECEAL 509
VLTSHSMEECEAL
Sbjct: 1979 VLTSHSMEECEAL 1991
>AK056533-1|BAB71208.1| 865|Homo sapiens protein ( Homo sapiens cDNA
FLJ31971 fis, clone NT2RP7008137, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
Length = 865
Score = 74.5 bits (175), Expect = 4e-13
Identities = 58/252 (23%), Positives = 112/252 (44%), Gaps = 12/252 (4%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVH-RLIGYCPQFDALFDNL 184
GLLG NGAGK++ +L GD + G + +S D + +GYCPQ + L+ +
Sbjct: 553 GLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDT 612
Query: 185 TARETLQIFCLLRGIPQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQKEK*VXXXXC*A 364
T +E +I+ ++G+ D+ ++S + L +K + +++ + C A
Sbjct: 613 TLQEHFEIYGAVKGM--SASDMKEVISRITHGLD---LKEHLQKTVKKLPAGIKRKLCFA 667
Query: 365 LRR*FSWMNQQQAWILXXXXXXXXXXXXXXXXXXXXXD---------VTQH--GGVRGSC 511
L S + Q +L +T H C
Sbjct: 668 L----SMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVC 723
Query: 512 SKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVKL 691
++ +MV+G+L C+G++QHLKS+F +GY + IK + + + ++ R+ + ++ F
Sbjct: 724 DRVAIMVSGQLRCIGTVQHLKSRFGKGYFLEIKLKDWIE-NLEVDRLQREIQYIFPNASR 782
Query: 692 VETYLGMSTYHV 727
E++ + Y +
Sbjct: 783 QESFSSILAYKI 794
Score = 46.8 bits (106), Expect = 8e-05
Identities = 24/64 (37%), Positives = 32/64 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R+ L H K V + AG KRK+ LDEP+TGMDP +K+ +WR
Sbjct: 638 RITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRA 697
Query: 439 ISSA 450
I +A
Sbjct: 698 IRTA 701
>AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant 1
protein.
Length = 1440
Score = 68.9 bits (161), Expect = 2e-11
Identities = 30/74 (40%), Positives = 45/74 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A ++GH +R + ++ + +G CPQ + LFD LT
Sbjct: 373 LGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVE 432
Query: 194 ETLQIFCLLRGIPQ 235
E L + L+ + Q
Sbjct: 433 EHLWFYSRLKSMAQ 446
Score = 39.1 bits (87), Expect = 0.017
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
V S G KRK+S LDEPT G+DP ++R +W
Sbjct: 470 VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIW 512
>AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9
protein.
Length = 1624
Score = 68.1 bits (159), Expect = 3e-11
Identities = 33/88 (37%), Positives = 56/88 (63%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLT 187
GLLG NGAGK++T +M+TGD + + G ++ G + +GYCPQ +AL+ NLT
Sbjct: 1323 GLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPL----GFLGYCPQENALWPNLT 1378
Query: 188 ARETLQIFCLLRGIPQRVGDVLVIVSLL 271
R+ L+++ ++G+ R GD ++ ++ L
Sbjct: 1379 VRQHLEVYAAVKGL--RKGDAMIAITRL 1404
Score = 57.2 bits (132), Expect = 6e-08
Identities = 26/75 (34%), Positives = 47/75 (62%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR--AHVQDVHRLIGYCPQFDALFDNL 184
LLG +GAGKT+ +L+G + + G V+ H++ A ++++ + G+CPQ + F L
Sbjct: 515 LLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL 574
Query: 185 TARETLQIFCLLRGI 229
T +E L++F ++GI
Sbjct: 575 TVKENLRLFAKIKGI 589
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/37 (48%), Positives = 29/37 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS 619
C ++ +MV+GRL C+GS+QHLKSKF + Y + +K ++
Sbjct: 1488 CDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKLKN 1524
Score = 35.1 bits (77), Expect = 0.27
Identities = 17/46 (36%), Positives = 23/46 (50%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGI 441
V S G KRK+ LDEP+TGMDP ++ +W+ I
Sbjct: 1418 VKTLSEGIKRKLRFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVI 1463
Score = 34.7 bits (76), Expect = 0.36
Identities = 18/58 (31%), Positives = 24/58 (41%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ EL D S G RK++ LDEPT G+DP S+ +W
Sbjct: 600 RVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIW 657
>AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette
sub-family A member 9 protein.
Length = 1624
Score = 68.1 bits (159), Expect = 3e-11
Identities = 33/88 (37%), Positives = 56/88 (63%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLT 187
GLLG NGAGK++T +M+TGD + + G ++ G + +GYCPQ +AL+ NLT
Sbjct: 1323 GLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPL----GFLGYCPQENALWPNLT 1378
Query: 188 ARETLQIFCLLRGIPQRVGDVLVIVSLL 271
R+ L+++ ++G+ R GD ++ ++ L
Sbjct: 1379 VRQHLEVYAAVKGL--RKGDAMIAITRL 1404
Score = 57.2 bits (132), Expect = 6e-08
Identities = 26/75 (34%), Positives = 47/75 (62%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR--AHVQDVHRLIGYCPQFDALFDNL 184
LLG +GAGKT+ +L+G + + G V+ H++ A ++++ + G+CPQ + F L
Sbjct: 515 LLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL 574
Query: 185 TARETLQIFCLLRGI 229
T +E L++F ++GI
Sbjct: 575 TVKENLRLFAKIKGI 589
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/37 (48%), Positives = 29/37 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS 619
C ++ +MV+GRL C+GS+QHLKSKF + Y + +K ++
Sbjct: 1488 CDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKLKN 1524
Score = 35.1 bits (77), Expect = 0.27
Identities = 17/46 (36%), Positives = 23/46 (50%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGI 441
V S G KRK+ LDEP+TGMDP ++ +W+ I
Sbjct: 1418 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVI 1463
Score = 34.7 bits (76), Expect = 0.36
Identities = 18/58 (31%), Positives = 24/58 (41%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ EL D S G RK++ LDEPT G+DP S+ +W
Sbjct: 600 RVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIW 657
>AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette
sub-family A member 9 protein.
Length = 1624
Score = 68.1 bits (159), Expect = 3e-11
Identities = 33/88 (37%), Positives = 56/88 (63%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLT 187
GLLG NGAGK++T +M+TGD + + G ++ G + +GYCPQ +AL+ NLT
Sbjct: 1323 GLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPL----GFLGYCPQENALWPNLT 1378
Query: 188 ARETLQIFCLLRGIPQRVGDVLVIVSLL 271
R+ L+++ ++G+ R GD ++ ++ L
Sbjct: 1379 VRQHLEVYAAVKGL--RKGDAMIAITRL 1404
Score = 57.2 bits (132), Expect = 6e-08
Identities = 26/75 (34%), Positives = 47/75 (62%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR--AHVQDVHRLIGYCPQFDALFDNL 184
LLG +GAGKT+ +L+G + + G V+ H++ A ++++ + G+CPQ + F L
Sbjct: 515 LLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL 574
Query: 185 TARETLQIFCLLRGI 229
T +E L++F ++GI
Sbjct: 575 TVKENLRLFAKIKGI 589
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/37 (48%), Positives = 29/37 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS 619
C ++ +MV+GRL C+GS+QHLKSKF + Y + +K ++
Sbjct: 1488 CDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKLKN 1524
Score = 35.1 bits (77), Expect = 0.27
Identities = 17/46 (36%), Positives = 23/46 (50%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGI 441
V S G KRK+ LDEP+TGMDP ++ +W+ I
Sbjct: 1418 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVI 1463
Score = 34.7 bits (76), Expect = 0.36
Identities = 18/58 (31%), Positives = 24/58 (41%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ EL D S G RK++ LDEPT G+DP S+ +W
Sbjct: 600 RVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIW 657
>BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein.
Length = 1621
Score = 66.9 bits (156), Expect = 7e-11
Identities = 34/88 (38%), Positives = 55/88 (62%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLT 187
GLLG NGAGK+++ +++TGD + + G L+ G D +GYCPQ +AL+ NLT
Sbjct: 1320 GLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGG----DALEFLGYCPQENALWPNLT 1375
Query: 188 ARETLQIFCLLRGIPQRVGDVLVIVSLL 271
R+ L+++ ++G+ R GD V ++ L
Sbjct: 1376 VRQHLEVYAAVKGL--RKGDAEVAITRL 1401
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 50/80 (62%), Gaps = 3/80 (3%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH--SVRAHVQDVHRLIGYCPQFDALFDNL 184
+LG +GAGK++ +L+G + + G ++ + S A ++++ +L G CPQ + FD L
Sbjct: 514 ILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKLTGVCPQSNVQFDFL 573
Query: 185 TARETLQIFCLLRGI-PQRV 241
T RE L++F ++GI PQ V
Sbjct: 574 TVRENLRLFAKIKGILPQEV 593
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/37 (48%), Positives = 29/37 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS 619
C ++ +MV+GRL C+GS+QHLKSKF + Y + +K ++
Sbjct: 1485 CDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVKN 1521
Score = 37.9 bits (84), Expect = 0.039
Identities = 20/58 (34%), Positives = 26/58 (44%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D S G KRK++ LDEPT G+DP S+ VW
Sbjct: 599 RVLLELEMKNIQDVLAQNLSGGQKRKLTFGIAILGDPQIFLLDEPTAGLDPFSRHQVW 656
Score = 36.3 bits (80), Expect = 0.12
Identities = 17/46 (36%), Positives = 23/46 (50%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGI 441
V S G KRK+ LDEP+TGMDP ++ +W+ I
Sbjct: 1415 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAI 1460
>AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein.
Length = 1591
Score = 66.9 bits (156), Expect = 7e-11
Identities = 34/88 (38%), Positives = 55/88 (62%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLT 187
GLLG NGAGK+++ +++TGD + + G L+ G D +GYCPQ +AL+ NLT
Sbjct: 1290 GLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGG----DALEFLGYCPQENALWPNLT 1345
Query: 188 ARETLQIFCLLRGIPQRVGDVLVIVSLL 271
R+ L+++ ++G+ R GD V ++ L
Sbjct: 1346 VRQHLEVYAAVKGL--RKGDAEVAITRL 1371
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 50/80 (62%), Gaps = 3/80 (3%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH--SVRAHVQDVHRLIGYCPQFDALFDNL 184
+LG +GAGK++ +L+G + + G ++ + S A ++++ +L G CPQ + FD L
Sbjct: 524 ILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKLTGVCPQSNVQFDFL 583
Query: 185 TARETLQIFCLLRGI-PQRV 241
T RE L++F ++GI PQ V
Sbjct: 584 TVRENLRLFAKIKGILPQEV 603
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/37 (48%), Positives = 29/37 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRS 619
C ++ +MV+GRL C+GS+QHLKSKF + Y + +K ++
Sbjct: 1455 CDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVKN 1491
Score = 36.3 bits (80), Expect = 0.12
Identities = 17/46 (36%), Positives = 23/46 (50%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGI 441
V S G KRK+ LDEP+TGMDP ++ +W+ I
Sbjct: 1385 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAI 1430
Score = 30.3 bits (65), Expect = 7.8
Identities = 11/17 (64%), Positives = 13/17 (76%)
Frame = +1
Query: 382 LDEPTTGMDPASKRLVW 432
LDEPT G+DP S+ VW
Sbjct: 610 LDEPTAGLDPFSRHQVW 626
>BX640746-1|CAE45856.1| 431|Homo sapiens hypothetical protein
protein.
Length = 431
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
LLG +G GK++ +L G SDG A ++GH V + + ++IG CPQ D FD L
Sbjct: 183 LLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVL 242
Query: 185 TARETLQIFCLLRGIPQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQKEK 337
T E L I ++GIP +++ V + DL TIK + L +K
Sbjct: 243 TVEENLSILASIKGIP--ANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQK 291
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
++ ++L D + + S G KRK+S LDEPT GMDP S+ +VW
Sbjct: 268 KVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVW 325
>AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5
protein.
Length = 1642
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
LLG +G GK++ +L G SDG A ++GH V + + ++IG CPQ D FD L
Sbjct: 512 LLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVL 571
Query: 185 TARETLQIFCLLRGIPQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQKEK 337
T E L I ++GIP +++ V + DL TIK + L +K
Sbjct: 572 TVEENLSILASIKGIP--ANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQK 620
Score = 52.4 bits (120), Expect = 2e-06
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR-AHVQDVHRLIGYCPQFDALFDNL 184
GLLG NGAGK++ +L GD + G + +S + D + +GYCPQ + L+ +
Sbjct: 1330 GLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDT 1389
Query: 185 TARETLQIFCLLRGI 229
T +E +I+ ++G+
Sbjct: 1390 TLQEHFEIYGAVKGM 1404
Score = 52.4 bits (120), Expect = 2e-06
Identities = 22/73 (30%), Positives = 45/73 (61%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+G+L C+G++QHLKSKF +GY + IK + + + ++ R+ + ++ F
Sbjct: 1500 CDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIE-NLEVDRLQREIQYIFPNAS 1558
Query: 689 LVETYLGMSTYHV 727
E++ + Y +
Sbjct: 1559 RQESFSSILAYKI 1571
Score = 47.2 bits (107), Expect = 6e-05
Identities = 24/64 (37%), Positives = 32/64 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R+ L H K V + AG KRK+ LDEP+TGMDP +K+ +WR
Sbjct: 1415 RITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRA 1474
Query: 439 ISSA 450
I +A
Sbjct: 1475 IRTA 1478
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
++ ++L D + + S G KRK+S LDEPT GMDP S+ +VW
Sbjct: 597 KVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVW 654
>AJ512612-1|CAD54757.1| 925|Homo sapiens ABCA5 transporter protein.
Length = 925
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
LLG +G GK++ +L G SDG A ++GH V + + ++IG CPQ D FD L
Sbjct: 512 LLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVL 571
Query: 185 TARETLQIFCLLRGIPQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQKEK 337
T E L I ++GIP +++ V + DL TIK + L +K
Sbjct: 572 TVEENLSILASIKGIP--ANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQK 620
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
++ ++L D + + S G KRK+S LDEPT GMDP S+ +VW
Sbjct: 597 KVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVW 654
>AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette
protein protein.
Length = 1642
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
LLG +G GK++ +L G SDG A ++GH V + + ++IG CPQ D FD L
Sbjct: 512 LLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVL 571
Query: 185 TARETLQIFCLLRGIPQRVGDVLVIVSLLNWDLSYTTIKRFMSAALEQKEK 337
T E L I ++GIP +++ V + DL TIK + L +K
Sbjct: 572 TVEENLSILASIKGIP--ANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQK 620
Score = 52.4 bits (120), Expect = 2e-06
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVH-RLIGYCPQFDALFDNL 184
GLLG NGAGK++ +L GD + G + +S + D + +GYCPQ + L+ +
Sbjct: 1330 GLLGPNGAGKSTIINILVGDIEPTSGQIFLGDYSSESSEDDDSLKCMGYCPQINPLWPDT 1389
Query: 185 TARETLQIFCLLRGI 229
T +E +I+ ++G+
Sbjct: 1390 TLQEHFEIYGAVKGM 1404
Score = 52.4 bits (120), Expect = 2e-06
Identities = 22/73 (30%), Positives = 45/73 (61%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+G+L C+G++QHLKSKF +GY + IK + + + ++ R+ + ++ F
Sbjct: 1500 CDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIE-NLEVDRLQREIQYIFPNAS 1558
Query: 689 LVETYLGMSTYHV 727
E++ + Y +
Sbjct: 1559 RQESFSSILAYKI 1571
Score = 47.2 bits (107), Expect = 6e-05
Identities = 24/64 (37%), Positives = 32/64 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R+ L H K V + AG KRK+ LDEP+TGMDP +K+ +WR
Sbjct: 1415 RITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRA 1474
Query: 439 ISSA 450
I +A
Sbjct: 1475 IRTA 1478
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
++ ++L D + + S G KRK+S LDEPT GMDP S+ +VW
Sbjct: 597 KVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVW 654
>AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens
cDNA FLJ46729 fis, clone TRACH3019370, weakly similar
to ATP-binding cassette, sub-family A, member 1. ).
Length = 851
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/75 (42%), Positives = 45/75 (60%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTA 190
LLG NGAGKT+ MLTG + G +++G +++ + V +G CPQ D L DNLT
Sbjct: 628 LLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTV 687
Query: 191 RETLQIFCLLRGIPQ 235
RE L +F ++ PQ
Sbjct: 688 REHLLLFASIKA-PQ 701
Score = 41.5 bits (93), Expect = 0.003
Identities = 22/61 (36%), Positives = 28/61 (45%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
H K+ S G KRK+S LDEPT+G+DP S+ +W I GR
Sbjct: 723 HQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLW-DILLKYREGRH 781
Query: 469 W 471
W
Sbjct: 782 W 782
>AK130814-1|BAC85435.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ27304 fis, clone TMS05176, highly similar to
ATP-binding cassette, sub-family A, member 1. ).
Length = 546
Score = 62.9 bits (146), Expect = 1e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +2
Query: 14 LGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTAR 193
LG NGAGKT+T +LTG + G A + G +R+ + + + +G CPQ + LFD LT
Sbjct: 106 LGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVE 165
Query: 194 ETLQIFCLLRGIPQR 238
E + + L+G+ ++
Sbjct: 166 EHIWFYARLKGLSEK 180
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 203 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 246
Score = 31.5 bits (68), Expect = 3.4
Identities = 10/31 (32%), Positives = 21/31 (67%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGYTIVI 607
++ ++ +G+LCC+GS LK++ GY + +
Sbjct: 274 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTL 304
>AL807752-19|CAI12765.1| 184|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), memberide 2 protein.
Length = 184
Score = 61.7 bits (143), Expect = 3e-09
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNGRL CLGS+QHLK++F GY I ++ +S + D+ R + +NF E
Sbjct: 11 CTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKS-SQSVKDVVR---FFNRNFPEAM 66
Query: 689 LVETYLGMSTYHVSS 733
L E + Y + S
Sbjct: 67 LKERHHTKVQYQLKS 81
>AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette
sub-family A member 10 protein.
Length = 1543
Score = 61.3 bits (142), Expect = 4e-09
Identities = 35/111 (31%), Positives = 65/111 (58%), Gaps = 4/111 (3%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR--AHVQDVHRLIGYCPQFDALFDNL 184
+LG NGAGK++ +L+G + ++G A ++ + ++++ + IG+CPQF+ FD L
Sbjct: 425 ILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFNFQFDFL 484
Query: 185 TARETLQIFCLLRGI-PQRV-GDVLVIVSLLNWDLSYTTIKRFMSAALEQK 331
T RE L++F ++GI P+ V +V I+ L+ I + +S ++K
Sbjct: 485 TVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIAKKLSGGQKRK 535
Score = 60.5 bits (140), Expect = 6e-09
Identities = 28/76 (36%), Positives = 50/76 (65%), Gaps = 2/76 (2%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGH--SVRAHVQDVHRLIGYCPQFDALFDN 181
GLLG NGAGK+++ +M+TG + + G ++ G SVR + + +GYCPQ ++L+
Sbjct: 1236 GLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPK 1295
Query: 182 LTARETLQIFCLLRGI 229
LT +E L+++ ++G+
Sbjct: 1296 LTMKEHLELYAAVKGL 1311
Score = 48.0 bits (109), Expect = 4e-05
Identities = 25/71 (35%), Positives = 39/71 (54%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+G L C+GS+QHLK+KF + Y + IK + T ++ T I K F +
Sbjct: 1407 CDRMAMMVSGTLRCIGSIQHLKNKFGRDYLLEIKMKEPTQVEALHTEI----LKLFPQAA 1462
Query: 689 LVETYLGMSTY 721
E Y + Y
Sbjct: 1463 WQERYSSLMAY 1473
Score = 38.7 bits (86), Expect = 0.022
Identities = 20/58 (34%), Positives = 27/58 (46%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D + S G KRK++ LDEPT G+DP S+ VW
Sbjct: 510 RIIMELDMQSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVW 567
Score = 34.7 bits (76), Expect = 0.36
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V S G KRK+ LDEP TGMDP ++ +W+ + + V
Sbjct: 1337 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATV 1386
>AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette
sub-family A member 10 protein.
Length = 1543
Score = 61.3 bits (142), Expect = 4e-09
Identities = 35/111 (31%), Positives = 65/111 (58%), Gaps = 4/111 (3%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR--AHVQDVHRLIGYCPQFDALFDNL 184
+LG NGAGK++ +L+G + ++G A ++ + ++++ + IG+CPQF+ FD L
Sbjct: 425 ILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFNFQFDFL 484
Query: 185 TARETLQIFCLLRGI-PQRV-GDVLVIVSLLNWDLSYTTIKRFMSAALEQK 331
T RE L++F ++GI P+ V +V I+ L+ I + +S ++K
Sbjct: 485 TVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIAKKLSGGQKRK 535
Score = 60.5 bits (140), Expect = 6e-09
Identities = 28/76 (36%), Positives = 50/76 (65%), Gaps = 2/76 (2%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGH--SVRAHVQDVHRLIGYCPQFDALFDN 181
GLLG NGAGK+++ +M+TG + + G ++ G SVR + + +GYCPQ ++L+
Sbjct: 1236 GLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPK 1295
Query: 182 LTARETLQIFCLLRGI 229
LT +E L+++ ++G+
Sbjct: 1296 LTMKEHLELYAAVKGL 1311
Score = 48.0 bits (109), Expect = 4e-05
Identities = 25/71 (35%), Positives = 39/71 (54%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+G L C+GS+QHLK+KF + Y + IK + T ++ T I K F +
Sbjct: 1407 CDRMAMMVSGTLRCIGSIQHLKNKFGRDYLLEIKMKEPTQVEALHTEI----LKLFPQAA 1462
Query: 689 LVETYLGMSTY 721
E Y + Y
Sbjct: 1463 WQERYSSLMAY 1473
Score = 38.7 bits (86), Expect = 0.022
Identities = 20/58 (34%), Positives = 27/58 (46%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D + S G KRK++ LDEPT G+DP S+ VW
Sbjct: 510 RIIMELDMQSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVW 567
Score = 34.7 bits (76), Expect = 0.36
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V S G KRK+ LDEP TGMDP ++ +W+ + + V
Sbjct: 1337 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATV 1386
>AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A10
protein.
Length = 1543
Score = 61.3 bits (142), Expect = 4e-09
Identities = 35/111 (31%), Positives = 65/111 (58%), Gaps = 4/111 (3%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR--AHVQDVHRLIGYCPQFDALFDNL 184
+LG NGAGK++ +L+G + ++G A ++ + ++++ + IG+CPQF+ FD L
Sbjct: 425 ILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFNFQFDFL 484
Query: 185 TARETLQIFCLLRGI-PQRV-GDVLVIVSLLNWDLSYTTIKRFMSAALEQK 331
T RE L++F ++GI P+ V +V I+ L+ I + +S ++K
Sbjct: 485 TVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIAKKLSGGQKRK 535
Score = 60.5 bits (140), Expect = 6e-09
Identities = 28/76 (36%), Positives = 50/76 (65%), Gaps = 2/76 (2%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGH--SVRAHVQDVHRLIGYCPQFDALFDN 181
GLLG NGAGK+++ +M+TG + + G ++ G SVR + + +GYCPQ ++L+
Sbjct: 1236 GLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPK 1295
Query: 182 LTARETLQIFCLLRGI 229
LT +E L+++ ++G+
Sbjct: 1296 LTMKEHLELYAAVKGL 1311
Score = 48.0 bits (109), Expect = 4e-05
Identities = 25/71 (35%), Positives = 39/71 (54%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+G L C+GS+QHLK+KF + Y + IK + T ++ T I K F +
Sbjct: 1407 CDRMAMMVSGTLRCIGSIQHLKNKFGRDYLLEIKMKEPTQVEALHTEI----LKLFPQAA 1462
Query: 689 LVETYLGMSTY 721
E Y + Y
Sbjct: 1463 WQERYSSLMAY 1473
Score = 38.7 bits (86), Expect = 0.022
Identities = 20/58 (34%), Positives = 27/58 (46%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D + S G KRK++ LDEPT G+DP S+ VW
Sbjct: 510 RIIMELDMQSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVW 567
Score = 34.7 bits (76), Expect = 0.36
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V S G KRK+ LDEP TGMDP ++ +W+ + + V
Sbjct: 1337 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATV 1386
>AL080207-1|CAB45776.1| 196|Homo sapiens hypothetical protein
protein.
Length = 196
Score = 61.3 bits (142), Expect = 4e-09
Identities = 26/73 (35%), Positives = 47/73 (64%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNG+ C+GSLQH+KS+F +G+T+ + ++ +T+ +M+ +F +
Sbjct: 57 CTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNKVTMETLTK---FMQLHFPKTY 113
Query: 689 LVETYLGMSTYHV 727
L + +L M YHV
Sbjct: 114 LKDQHLSMLEYHV 126
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +1
Query: 382 LDEPTTGMDPASKRLVWRGISSAV 453
LDEP++GMDP SKR +W+ IS V
Sbjct: 14 LDEPSSGMDPKSKRHLWKIISEEV 37
Score = 32.3 bits (70), Expect = 1.9
Identities = 13/17 (76%), Positives = 15/17 (88%)
Frame = +3
Query: 459 RAHVVLTSHSMEECEAL 509
+ V+LTSHSMEECEAL
Sbjct: 40 KCSVILTSHSMEECEAL 56
>AC114780-1|AAY24230.1| 182|Homo sapiens unknown protein.
Length = 182
Score = 61.3 bits (142), Expect = 4e-09
Identities = 26/73 (35%), Positives = 47/73 (64%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C++L +MVNG+ C+GSLQH+KS+F +G+T+ + ++ +T+ +M+ +F +
Sbjct: 43 CTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNKVTMETLTK---FMQLHFPKTY 99
Query: 689 LVETYLGMSTYHV 727
L + +L M YHV
Sbjct: 100 LKDQHLSMLEYHV 112
Score = 34.3 bits (75), Expect = 0.48
Identities = 14/23 (60%), Positives = 18/23 (78%)
Frame = +1
Query: 385 DEPTTGMDPASKRLVWRGISSAV 453
DEP++GMDP SKR +W+ IS V
Sbjct: 1 DEPSSGMDPKSKRHLWKIISEEV 23
Score = 32.3 bits (70), Expect = 1.9
Identities = 13/17 (76%), Positives = 15/17 (88%)
Frame = +3
Query: 459 RAHVVLTSHSMEECEAL 509
+ V+LTSHSMEECEAL
Sbjct: 26 KCSVILTSHSMEECEAL 42
>BC051320-1|AAH51320.1| 419|Homo sapiens ABCA10 protein protein.
Length = 419
Score = 60.5 bits (140), Expect = 6e-09
Identities = 28/76 (36%), Positives = 50/76 (65%), Gaps = 2/76 (2%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGH--SVRAHVQDVHRLIGYCPQFDALFDN 181
GLLG NGAGK+++ +M+TG + + G ++ G SVR + + +GYCPQ ++L+
Sbjct: 112 GLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPK 171
Query: 182 LTARETLQIFCLLRGI 229
LT +E L+++ ++G+
Sbjct: 172 LTMKEHLELYAAVKGL 187
Score = 48.0 bits (109), Expect = 4e-05
Identities = 25/71 (35%), Positives = 39/71 (54%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+G L C+GS+QHLK+KF + Y + IK + T ++ T I K F +
Sbjct: 283 CDRMAMMVSGTLRCIGSIQHLKNKFGRDYLLEIKMKEPTQVEALHTEI----LKLFPQAA 338
Query: 689 LVETYLGMSTY 721
E Y + Y
Sbjct: 339 WQERYSSLMAY 349
Score = 34.7 bits (76), Expect = 0.36
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V S G KRK+ LDEP TGMDP ++ +W+ + + V
Sbjct: 213 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATV 262
>AK074491-1|BAC11021.1| 483|Homo sapiens protein ( Homo sapiens
cDNA FLJ90010 fis, clone HEMBA1000349, weakly similar to
ATP-BINDING CASSETTE TRANSPORTER 1. ).
Length = 483
Score = 57.2 bits (132), Expect = 6e-08
Identities = 26/75 (34%), Positives = 47/75 (62%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR--AHVQDVHRLIGYCPQFDALFDNL 184
LLG +GAGKT+ +L+G + + G V+ H++ A ++++ + G+CPQ + F L
Sbjct: 142 LLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL 201
Query: 185 TARETLQIFCLLRGI 229
T +E L++F ++GI
Sbjct: 202 TVKENLRLFAKIKGI 216
Score = 34.7 bits (76), Expect = 0.36
Identities = 18/58 (31%), Positives = 24/58 (41%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ EL D S G RK++ LDEPT G+DP S+ +W
Sbjct: 227 RVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIW 284
>AK057068-1|BAB71359.1| 856|Homo sapiens protein ( Homo sapiens
cDNA FLJ32506 fis, clone SMINT1000042, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 3. ).
Length = 856
Score = 57.2 bits (132), Expect = 6e-08
Identities = 26/75 (34%), Positives = 47/75 (62%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR--AHVQDVHRLIGYCPQFDALFDNL 184
LLG +GAGKT+ +L+G + + G V+ H++ A ++++ + G+CPQ + F L
Sbjct: 515 LLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL 574
Query: 185 TARETLQIFCLLRGI 229
T +E L++F ++GI
Sbjct: 575 TVKENLRLFAKIKGI 589
Score = 34.7 bits (76), Expect = 0.36
Identities = 18/58 (31%), Positives = 24/58 (41%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ EL D S G RK++ LDEPT G+DP S+ +W
Sbjct: 600 RVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIW 657
>AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6
protein.
Length = 1617
Score = 56.4 bits (130), Expect = 1e-07
Identities = 30/75 (40%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHG-HSVRAHVQDVHRLIGYCPQFDALFDNL 184
GLLG NGAGK+S+ RM++G + + G+ + G SV H +GYCPQ + L+ L
Sbjct: 1317 GLLGPNGAGKSSSIRMISGITKPTAGEVELKGCSSVLGH-------LGYCPQENVLWPML 1369
Query: 185 TARETLQIFCLLRGI 229
T RE L+++ ++G+
Sbjct: 1370 TLREHLEVYAAVKGL 1384
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/75 (32%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
+LG +GAGK+S +L G + ++G ++ ++ ++++ ++ G CPQF+ FD L
Sbjct: 512 ILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDIL 571
Query: 185 TARETLQIFCLLRGI 229
T +E L +F ++GI
Sbjct: 572 TVKENLSLFAKIKGI 586
Score = 50.4 bits (115), Expect = 7e-06
Identities = 25/76 (32%), Positives = 42/76 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+GRL C+GS+QHLK+K + Y + +K + S +T + + K F +
Sbjct: 1480 CDRVAIMVSGRLRCIGSIQHLKNKLGKDYILELKVK----ETSQVTLVHTEILKLFPQAA 1535
Query: 689 LVETYLGMSTYHVSSA 736
E Y + TY + A
Sbjct: 1536 GQERYSSLLTYKLPVA 1551
Score = 39.9 bits (89), Expect = 0.010
Identities = 21/58 (36%), Positives = 27/58 (46%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D S G KRK++ LDEPTTG+DP S+ VW
Sbjct: 597 RILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVW 654
Score = 36.7 bits (81), Expect = 0.090
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V + +AG RK+ LDEP+TG+DP ++ +W+ I + V
Sbjct: 1410 VQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVV 1459
>AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6
protein.
Length = 1617
Score = 56.4 bits (130), Expect = 1e-07
Identities = 30/75 (40%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHG-HSVRAHVQDVHRLIGYCPQFDALFDNL 184
GLLG NGAGK+S+ RM++G + + G+ + G SV H +GYCPQ + L+ L
Sbjct: 1317 GLLGPNGAGKSSSIRMISGITKPTAGEVELKGCSSVLGH-------LGYCPQENVLWPML 1369
Query: 185 TARETLQIFCLLRGI 229
T RE L+++ ++G+
Sbjct: 1370 TLREHLEVYAAVKGL 1384
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/75 (32%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
+LG +GAGK+S +L G + ++G ++ ++ ++++ ++ G CPQF+ FD L
Sbjct: 512 ILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDIL 571
Query: 185 TARETLQIFCLLRGI 229
T +E L +F ++GI
Sbjct: 572 TVKENLSLFAKIKGI 586
Score = 50.4 bits (115), Expect = 7e-06
Identities = 25/76 (32%), Positives = 42/76 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+GRL C+GS+QHLK+K + Y + +K + S +T + + K F +
Sbjct: 1480 CDRVAIMVSGRLRCIGSIQHLKNKLGKDYILELKVK----ETSQVTLVHTEILKLFPQAA 1535
Query: 689 LVETYLGMSTYHVSSA 736
E Y + TY + A
Sbjct: 1536 GQERYSSLLTYKLPVA 1551
Score = 39.9 bits (89), Expect = 0.010
Identities = 21/58 (36%), Positives = 27/58 (46%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D S G KRK++ LDEPTTG+DP S+ VW
Sbjct: 597 RILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVW 654
Score = 36.7 bits (81), Expect = 0.090
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V + +AG RK+ LDEP+TG+DP ++ +W+ I + V
Sbjct: 1410 VQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVV 1459
>BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein.
Length = 1500
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/75 (32%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
+LG +GAGK+S +L G + ++G ++ ++ ++++ ++ G CPQF+ FD L
Sbjct: 512 ILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDIL 571
Query: 185 TARETLQIFCLLRGI 229
T +E L +F ++GI
Sbjct: 572 TVKENLSLFAKIKGI 586
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/75 (38%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHG-HSVRAHVQDVHRLIGYCPQFDALFDNL 184
GLLG +GAGK+S+ RM++G + + G+ + G SV H +GYCPQ + L+ L
Sbjct: 1317 GLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGH-------LGYCPQENVLWPML 1369
Query: 185 TARETLQIFCLLRGI 229
T RE L+++ ++G+
Sbjct: 1370 TLREHLEVYAAVKGL 1384
Score = 39.9 bits (89), Expect = 0.010
Identities = 21/58 (36%), Positives = 27/58 (46%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D S G KRK++ LDEPTTG+DP S+ VW
Sbjct: 597 RILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVW 654
Score = 36.7 bits (81), Expect = 0.090
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V + +AG RK+ LDEP+TG+DP ++ +W+ I + V
Sbjct: 1410 VQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVV 1459
Score = 35.1 bits (77), Expect = 0.27
Identities = 12/21 (57%), Positives = 18/21 (85%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHL 571
C ++ +MV+GRL C+GS+QHL
Sbjct: 1480 CDRVAIMVSGRLRCIGSIQHL 1500
>BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein.
Length = 1500
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/75 (32%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
+LG +GAGK+S +L G + ++G ++ ++ ++++ ++ G CPQF+ FD L
Sbjct: 512 ILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDIL 571
Query: 185 TARETLQIFCLLRGI 229
T +E L +F ++GI
Sbjct: 572 TVKENLSLFAKIKGI 586
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/75 (38%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHG-HSVRAHVQDVHRLIGYCPQFDALFDNL 184
GLLG +GAGK+S+ RM++G + + G+ + G SV H +GYCPQ + L+ L
Sbjct: 1317 GLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGH-------LGYCPQENVLWPML 1369
Query: 185 TARETLQIFCLLRGI 229
T RE L+++ ++G+
Sbjct: 1370 TLREHLEVYAAVKGL 1384
Score = 39.9 bits (89), Expect = 0.010
Identities = 21/58 (36%), Positives = 27/58 (46%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D S G KRK++ LDEPTTG+DP S+ VW
Sbjct: 597 RILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVW 654
Score = 36.7 bits (81), Expect = 0.090
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V + +AG RK+ LDEP+TG+DP ++ +W+ I + V
Sbjct: 1410 VQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVV 1459
Score = 35.1 bits (77), Expect = 0.27
Identities = 12/21 (57%), Positives = 18/21 (85%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHL 571
C ++ +MV+GRL C+GS+QHL
Sbjct: 1480 CDRVAIMVSGRLRCIGSIQHL 1500
>AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6
protein.
Length = 1617
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/75 (32%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA--HVQDVHRLIGYCPQFDALFDNL 184
+LG +GAGK+S +L G + ++G ++ ++ ++++ ++ G CPQF+ FD L
Sbjct: 512 ILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDIL 571
Query: 185 TARETLQIFCLLRGI 229
T +E L +F ++GI
Sbjct: 572 TVKENLSLFAKIKGI 586
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/75 (38%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHG-HSVRAHVQDVHRLIGYCPQFDALFDNL 184
GLLG +GAGK+S+ RM++G + + G+ + G SV H +GYCPQ + L+ L
Sbjct: 1317 GLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGH-------LGYCPQENVLWPML 1369
Query: 185 TARETLQIFCLLRGI 229
T RE L+++ ++G+
Sbjct: 1370 TLREHLEVYAAVKGL 1384
Score = 50.4 bits (115), Expect = 7e-06
Identities = 25/76 (32%), Positives = 42/76 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+GRL C+GS+QHLK+K + Y + +K + S +T + + K F +
Sbjct: 1480 CDRVAIMVSGRLRCIGSIQHLKNKLGKDYILELKVK----ETSQVTLVHTEILKLFPQAA 1535
Query: 689 LVETYLGMSTYHVSSA 736
E Y + TY + A
Sbjct: 1536 GQERYSSLLTYKLPVA 1551
Score = 39.9 bits (89), Expect = 0.010
Identities = 21/58 (36%), Positives = 27/58 (46%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
R+ +EL D S G KRK++ LDEPTTG+DP S+ VW
Sbjct: 597 RILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVW 654
Score = 36.7 bits (81), Expect = 0.090
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V + +AG RK+ LDEP+TG+DP ++ +W+ I + V
Sbjct: 1410 VQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVV 1459
>AK097296-1|BAC04994.1| 815|Homo sapiens protein ( Homo sapiens
cDNA FLJ39977 fis, clone SPLEN2029295, moderately
similar to ATP-binding cassette, sub-family A member 8.
).
Length = 815
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/75 (38%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHG-HSVRAHVQDVHRLIGYCPQFDALFDNL 184
GLLG +GAGK+S+ RM++G + + G+ + G SV H +GYCPQ + L+ L
Sbjct: 515 GLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGH-------LGYCPQENVLWPML 567
Query: 185 TARETLQIFCLLRGI 229
T RE L+++ ++G+
Sbjct: 568 TLREHLEVYAAVKGL 582
Score = 50.4 bits (115), Expect = 7e-06
Identities = 25/76 (32%), Positives = 42/76 (55%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+GRL C+GS+QHLK+K + Y + +K + S +T + + K F +
Sbjct: 678 CDRVAIMVSGRLRCIGSIQHLKNKLGKDYILELKVK----ETSQVTLVHTEILKLFPQAA 733
Query: 689 LVETYLGMSTYHVSSA 736
E Y + TY + A
Sbjct: 734 GQERYSSLLTYKLPVA 749
Score = 36.7 bits (81), Expect = 0.090
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +1
Query: 304 VHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAV 453
V + +AG RK+ LDEP+TG+DP ++ +W+ I + V
Sbjct: 608 VQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVV 657
>AK091270-1|BAC03623.1| 293|Homo sapiens protein ( Homo sapiens
cDNA FLJ33951 fis, clone CTONG2018483, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
Length = 293
Score = 54.4 bits (125), Expect = 4e-07
Identities = 27/58 (46%), Positives = 32/58 (55%)
Frame = +1
Query: 289 HYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGG 462
H DK V S GTKRK+ST LDEP++GMDP SKR +W+ I V G
Sbjct: 84 HADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREG 141
Score = 52.0 bits (119), Expect = 2e-06
Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTI-VIKCRSGTDRDSDITRIDQYMKKNFNEV 685
C++L +MVNG CLGS QH+K++F GYT+ V C+ + ++K F +
Sbjct: 158 CTRLAIMVNGSFKCLGSPQHIKNRFGDGYTVKVWLCKEANQH----CTVSDHLKLYFPGI 213
Query: 686 KLVETYLGMSTYHV 727
+ +L + YHV
Sbjct: 214 QFKGQHLNLLEYHV 227
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 4/66 (6%)
Frame = +2
Query: 53 MLTGDARVSDGDALVH---GHSVR-AHVQDVHRLIGYCPQFDALFDNLTARETLQIFCLL 220
ML G+ ++ G A++ G +V + LIGYCPQ DAL + LT E L +C L
Sbjct: 1 MLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSL 60
Query: 221 RGIPQR 238
RGIP++
Sbjct: 61 RGIPRQ 66
Score = 30.7 bits (66), Expect = 5.9
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = +3
Query: 471 VLTSHSMEECEAL 509
VLTSHSMEECEAL
Sbjct: 145 VLTSHSMEECEAL 157
>U18236-1|AAA84437.2| 131|Homo sapiens ATP-binding cassette protein
protein.
Length = 131
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/66 (39%), Positives = 34/66 (51%)
Frame = +1
Query: 271 ELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSA 450
+L + DK S G KRK+ST FLDEPTTGMDP ++R +W I
Sbjct: 8 KLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDL 67
Query: 451 VGGGRT 468
+ GR+
Sbjct: 68 IKTGRS 73
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/14 (100%), Positives = 14/14 (100%)
Frame = +3
Query: 468 VVLTSHSMEECEAL 509
VVLTSHSMEECEAL
Sbjct: 74 VVLTSHSMEECEAL 87
>AK058170-1|BAB71700.1| 364|Homo sapiens protein ( Homo sapiens
cDNA FLJ25441 fis, clone TST08455. ).
Length = 364
Score = 52.4 bits (120), Expect = 2e-06
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR-AHVQDVHRLIGYCPQFDALFDNL 184
GLLG NGAGK++ +L GD + G + +S + D + +GYCPQ + L+ +
Sbjct: 52 GLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDT 111
Query: 185 TARETLQIFCLLRGI 229
T +E +I+ ++G+
Sbjct: 112 TLQEHFEIYGAVKGM 126
Score = 52.4 bits (120), Expect = 2e-06
Identities = 22/73 (30%), Positives = 45/73 (61%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+G+L C+G++QHLKSKF +GY + IK + + + ++ R+ + ++ F
Sbjct: 222 CDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIE-NLEVDRLQREIQYIFPNAS 280
Query: 689 LVETYLGMSTYHV 727
E++ + Y +
Sbjct: 281 RQESFSSILAYKI 293
Score = 47.2 bits (107), Expect = 6e-05
Identities = 24/64 (37%), Positives = 32/64 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R+ L H K V + AG KRK+ LDEP+TGMDP +K+ +WR
Sbjct: 137 RITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRA 196
Query: 439 ISSA 450
I +A
Sbjct: 197 IRTA 200
>AB067475-1|BAB67781.1| 737|Homo sapiens KIAA1888 protein protein.
Length = 737
Score = 52.4 bits (120), Expect = 2e-06
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVR-AHVQDVHRLIGYCPQFDALFDNL 184
GLLG NGAGK++ +L GD + G + +S + D + +GYCPQ + L+ +
Sbjct: 425 GLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDT 484
Query: 185 TARETLQIFCLLRGI 229
T +E +I+ ++G+
Sbjct: 485 TLQEHFEIYGAVKGM 499
Score = 52.4 bits (120), Expect = 2e-06
Identities = 22/73 (30%), Positives = 45/73 (61%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKSKFSQGYTIVIKCRSGTDRDSDITRIDQYMKKNFNEVK 688
C ++ +MV+G+L C+G++QHLKSKF +GY + IK + + + ++ R+ + ++ F
Sbjct: 595 CDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIE-NLEVDRLQREIQYIFPNAS 653
Query: 689 LVETYLGMSTYHV 727
E++ + Y +
Sbjct: 654 RQESFSSILAYKI 666
Score = 47.2 bits (107), Expect = 6e-05
Identities = 24/64 (37%), Positives = 32/64 (50%)
Frame = +1
Query: 259 RLAVELGFVVHYDKKVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRG 438
R+ L H K V + AG KRK+ LDEP+TGMDP +K+ +WR
Sbjct: 510 RITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRA 569
Query: 439 ISSA 450
I +A
Sbjct: 570 IRTA 573
>AF165306-1|AAD49852.1| 849|Homo sapiens ATP cassette binding
transporter 1 protein.
Length = 849
Score = 45.2 bits (102), Expect = 3e-04
Identities = 19/62 (30%), Positives = 35/62 (56%)
Frame = +2
Query: 53 MLTGDARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDNLTARETLQIFCLLRGIP 232
+LTG + G A + G +R+ + + + +G CPQ + LFD LT E + + L+G+
Sbjct: 2 ILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLS 61
Query: 233 QR 238
++
Sbjct: 62 EK 63
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 301 KVHECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVW 432
K + S G +RK+S LDEPT G+DP S+R +W
Sbjct: 86 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIW 129
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +2
Query: 515 KLTVMVNGRLCCLGSLQHLKSKFSQGY--TIVIK-CRSGTDRDSDITRIDQYMKKNFNEV 685
++ ++ +G+LCC+GS LK++ GY T+V K S + + Y+KK + V
Sbjct: 157 RIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKE-DSV 215
Query: 686 KLVETYLGMSTYHVS 730
+ G+ + H S
Sbjct: 216 SQSSSDAGLGSDHES 230
>BC113657-1|AAI13658.1| 673|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 8 (sterolin 2) protein.
Length = 673
Score = 35.1 bits (77), Expect = 0.27
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTG---DARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
++G +G G+ S ++TG ++ G ++G + Q V + + + Q + L N
Sbjct: 103 IIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQP--SSPQLVRKCVAHVRQHNQLLPN 160
Query: 182 LTARETLQIFCLLR 223
LT RETL +R
Sbjct: 161 LTVRETLAFIAQMR 174
>AF351824-1|AAK84663.1| 672|Homo sapiens sterolin-2 protein.
Length = 672
Score = 35.1 bits (77), Expect = 0.27
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTG---DARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
++G +G G+ S ++TG ++ G ++G + Q V + + + Q + L N
Sbjct: 103 IIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQP--SSPQLVRKCVAHVRQHNQLLPN 160
Query: 182 LTARETLQIFCLLR 223
LT RETL +R
Sbjct: 161 LTVRETLAFIAQMR 174
>AF324494-1|AAK84078.1| 673|Homo sapiens sterolin-2 protein.
Length = 673
Score = 35.1 bits (77), Expect = 0.27
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTG---DARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
++G +G G+ S ++TG ++ G ++G + Q V + + + Q + L N
Sbjct: 103 IIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQP--SSPQLVRKCVAHVRQHNQLLPN 160
Query: 182 LTARETLQIFCLLR 223
LT RETL +R
Sbjct: 161 LTVRETLAFIAQMR 174
>AF320294-1|AAG40004.1| 673|Homo sapiens ABCG8 protein.
Length = 673
Score = 35.1 bits (77), Expect = 0.27
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTG---DARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
++G +G G+ S ++TG ++ G ++G + Q V + + + Q + L N
Sbjct: 103 IIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQP--SSPQLVRKCVAHVRQHNQLLPN 160
Query: 182 LTARETLQIFCLLR 223
LT RETL +R
Sbjct: 161 LTVRETLAFIAQMR 174
>AC108476-2|AAY24011.1| 673|Homo sapiens unknown protein.
Length = 673
Score = 35.1 bits (77), Expect = 0.27
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTG---DARVSDGDALVHGHSVRAHVQDVHRLIGYCPQFDALFDN 181
++G +G G+ S ++TG ++ G ++G + Q V + + + Q + L N
Sbjct: 103 IIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQP--SSPQLVRKCVAHVRQHNQLLPN 160
Query: 182 LTARETLQIFCLLR 223
LT RETL +R
Sbjct: 161 LTVRETLAFIAQMR 174
>CR589949-2|CAM12888.1| 584|Homo sapiens intracisternal A
particle-promoted polypeptide protein.
Length = 584
Score = 33.9 bits (74), Expect = 0.63
Identities = 15/55 (27%), Positives = 26/55 (47%)
Frame = +3
Query: 399 RHGSCVEAARVARHQQRGGRRAHVVLTSHSMEECEALAPSSPSWSTAGSAVSARC 563
R G CV A + G +H L +++ E P S +W+ G+ +++RC
Sbjct: 523 RAGMCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEIGNMITSRC 577
>BX664740-2|CAM12889.1| 584|Homo sapiens intracisternal A
particle-promoted polypeptide protein.
Length = 584
Score = 33.9 bits (74), Expect = 0.63
Identities = 15/55 (27%), Positives = 26/55 (47%)
Frame = +3
Query: 399 RHGSCVEAARVARHQQRGGRRAHVVLTSHSMEECEALAPSSPSWSTAGSAVSARC 563
R G CV A + G +H L +++ E P S +W+ G+ +++RC
Sbjct: 523 RAGMCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEIGNMITSRC 577
>BT007451-1|AAP36119.1| 623|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 2 protein.
Length = 623
Score = 33.9 bits (74), Expect = 0.63
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH 106
L+G NGAGK++ ++LTG+ +DG H H
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSH 459
>BC001661-1|AAH01661.1| 623|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 2 protein.
Length = 623
Score = 33.9 bits (74), Expect = 0.63
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH 106
L+G NGAGK++ ++LTG+ +DG H H
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSH 459
>AL604028-4|CAM12886.1| 584|Homo sapiens intracisternal A
particle-promoted polypeptide protein.
Length = 584
Score = 33.9 bits (74), Expect = 0.63
Identities = 15/55 (27%), Positives = 26/55 (47%)
Frame = +3
Query: 399 RHGSCVEAARVARHQQRGGRRAHVVLTSHSMEECEALAPSSPSWSTAGSAVSARC 563
R G CV A + G +H L +++ E P S +W+ G+ +++RC
Sbjct: 523 RAGMCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEIGNMITSRC 577
>AJ005016-1|CAA06290.1| 550|Homo sapiens ABC transporter protein.
Length = 550
Score = 33.9 bits (74), Expect = 0.63
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH 106
L+G NGAGK++ ++LTG+ +DG H H
Sbjct: 355 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSH 386
>AF261092-1|AAG13903.1| 623|Homo sapiens iron inhibited ABC
transporter 1 protein.
Length = 623
Score = 33.9 bits (74), Expect = 0.63
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH 106
L+G NGAGK++ ++LTG+ +DG H H
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSH 459
>AF261091-1|AAG13902.1| 623|Homo sapiens iron inhibited ABC
transporter 2 protein.
Length = 623
Score = 33.9 bits (74), Expect = 0.63
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH 106
L+G NGAGK++ ++LTG+ +DG H H
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSH 459
>AF156857-1|AAD39007.1| 584|Homo sapiens actin-binding protein
protein.
Length = 584
Score = 33.9 bits (74), Expect = 0.63
Identities = 15/55 (27%), Positives = 26/55 (47%)
Frame = +3
Query: 399 RHGSCVEAARVARHQQRGGRRAHVVLTSHSMEECEALAPSSPSWSTAGSAVSARC 563
R G CV A + G +H L +++ E P S +W+ G+ +++RC
Sbjct: 523 RAGMCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEIGNMITSRC 577
>AC021097-3|AAS00379.1| 623|Homo sapiens unknown protein.
Length = 623
Score = 33.9 bits (74), Expect = 0.63
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH 106
L+G NGAGK++ ++LTG+ +DG H H
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSH 459
>AC021097-2|AAS00378.1| 634|Homo sapiens unknown protein.
Length = 634
Score = 33.9 bits (74), Expect = 0.63
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGH 106
L+G NGAGK++ ++LTG+ +DG H H
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSH 459
>BC112069-1|AAI12070.1| 66|Homo sapiens ABCA11 protein protein.
Length = 66
Score = 33.1 bits (72), Expect = 1.1
Identities = 12/23 (52%), Positives = 18/23 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKS 577
C ++ +MV+G L C+GS+Q LKS
Sbjct: 38 CDRVAIMVSGTLRCIGSIQQLKS 60
>BC105084-1|AAI05085.1| 66|Homo sapiens ABCA11 protein protein.
Length = 66
Score = 33.1 bits (72), Expect = 1.1
Identities = 12/23 (52%), Positives = 18/23 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKS 577
C ++ +MV+G L C+GS+Q LKS
Sbjct: 38 CDRVAIMVSGTLRCIGSIQQLKS 60
>BC099730-1|AAH99730.1| 66|Homo sapiens ABCA11 protein protein.
Length = 66
Score = 33.1 bits (72), Expect = 1.1
Identities = 12/23 (52%), Positives = 18/23 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKS 577
C ++ +MV+G L C+GS+Q LKS
Sbjct: 38 CDRVAIMVSGTLRCIGSIQQLKS 60
>BC098259-1|AAH98259.1| 66|Homo sapiens ABCA11 protein protein.
Length = 66
Score = 33.1 bits (72), Expect = 1.1
Identities = 12/23 (52%), Positives = 18/23 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKS 577
C ++ +MV+G L C+GS+Q LKS
Sbjct: 38 CDRVAIMVSGTLRCIGSIQQLKS 60
>BC098116-1|AAH98116.1| 66|Homo sapiens ABCA11 protein protein.
Length = 66
Score = 33.1 bits (72), Expect = 1.1
Identities = 12/23 (52%), Positives = 18/23 (78%)
Frame = +2
Query: 509 CSKLTVMVNGRLCCLGSLQHLKS 577
C ++ +MV+G L C+GS+Q LKS
Sbjct: 38 CDRVAIMVSGTLRCIGSIQQLKS 60
>AK024359-1|BAB14895.1| 156|Homo sapiens protein ( Homo sapiens
cDNA FLJ14297 fis, clone PLACE1008941. ).
Length = 156
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGH--SVRAHVQDVHRLIG 148
GLLG NGAGK+++ +M+TG + G ++ G+ SVR + + +G
Sbjct: 95 GLLGHNGAGKSTSIKMITGCTVPTAGVVVLQGNRASVRQQRDNSLKFLG 143
>AC092574-2|AAY41037.1| 156|Homo sapiens unknown protein.
Length = 156
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
Frame = +2
Query: 8 GLLGVNGAGKTSTFRMLTGDARVSDGDALVHGH--SVRAHVQDVHRLIG 148
GLLG NGAGK+++ +M+TG + G ++ G+ SVR + + +G
Sbjct: 95 GLLGHNGAGKSTSIKMITGCTVPTAGVVVLQGNRASVRQQRDNSLKFLG 143
>BC041091-1|AAH41091.1| 646|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 4 protein.
Length = 646
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/51 (33%), Positives = 25/51 (49%)
Frame = +1
Query: 316 SAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
S G +++++ F DEPT+G+D AS V + S GGRT
Sbjct: 202 SGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRT 252
>AJ308237-1|CAC87131.1| 646|Homo sapiens ABC transporter protein.
Length = 646
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/51 (33%), Positives = 25/51 (49%)
Frame = +1
Query: 316 SAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
S G +++++ F DEPT+G+D AS V + S GGRT
Sbjct: 202 SGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRT 252
>AJ300465-1|CAC17140.1| 627|Homo sapiens putative white family
ATP-binding cassette transporter protein.
Length = 627
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/51 (33%), Positives = 25/51 (49%)
Frame = +1
Query: 316 SAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASKRLVWRGISSAVGGGRT 468
S G +++++ F DEPT+G+D AS V + S GGRT
Sbjct: 183 SGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRT 233
>AK095260-1|BAC04513.1| 273|Homo sapiens protein ( Homo sapiens
cDNA FLJ37941 fis, clone CTONG2008269. ).
Length = 273
Score = 31.1 bits (67), Expect = 4.5
Identities = 17/36 (47%), Positives = 19/36 (52%)
Frame = -3
Query: 114 RTECPCTSASPSDTRASPVSMRKVLVLPAPLTPSRP 7
RTE P T A+PS RA P +R P P P RP
Sbjct: 110 RTEAPITQAAPSRRRAVPGGLR-----PLPTPPRRP 140
>BC150263-1|AAI50264.1| 1261|Homo sapiens cordon-bleu homolog (mouse)
protein.
Length = 1261
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/49 (32%), Positives = 22/49 (44%)
Frame = -1
Query: 461 PPPTALLMPRHTSRFDAGSMPVVGSSRKTNDEALNKATAVLIFLFVPAL 315
PP AL PR SRF G++ +R+ +A+ T VP L
Sbjct: 1212 PPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL 1260
>BC045771-1|AAH45771.1| 1146|Homo sapiens COBL protein protein.
Length = 1146
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/49 (32%), Positives = 22/49 (44%)
Frame = -1
Query: 461 PPPTALLMPRHTSRFDAGSMPVVGSSRKTNDEALNKATAVLIFLFVPAL 315
PP AL PR SRF G++ +R+ +A+ T VP L
Sbjct: 1097 PPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL 1145
>AL713786-1|CAD28543.1| 803|Homo sapiens hypothetical protein
protein.
Length = 803
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/49 (32%), Positives = 22/49 (44%)
Frame = -1
Query: 461 PPPTALLMPRHTSRFDAGSMPVVGSSRKTNDEALNKATAVLIFLFVPAL 315
PP AL PR SRF G++ +R+ +A+ T VP L
Sbjct: 754 PPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL 802
>AK092415-1|BAC03881.1| 703|Homo sapiens protein ( Homo sapiens
cDNA FLJ35096 fis, clone PLACE6006217, weakly similar to
GCN20 PROTEIN. ).
Length = 703
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
Frame = +2
Query: 5 FGLLGVNGAGKTSTFRML-TGDARVSDGDALVH 100
+GL+G NG GKT+ +ML T RVS +L+H
Sbjct: 200 YGLVGRNGLGKTTLLKMLATRSLRVSAHISLLH 232
>AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 30.7 bits (66), Expect = 5.9
Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA-HVQDVHRLIGYCPQFDALFDNLT 187
L+G +GAGK++ +++ +G V GH +R+ ++Q + IG Q LF
Sbjct: 453 LVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTI 512
Query: 188 A 190
A
Sbjct: 513 A 513
>AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 30.7 bits (66), Expect = 5.9
Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA-HVQDVHRLIGYCPQFDALFDNLT 187
L+G +GAGK++ +++ +G V GH +R+ ++Q + IG Q LF
Sbjct: 453 LVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTI 512
Query: 188 A 190
A
Sbjct: 513 A 513
>AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein.
Length = 870
Score = 30.7 bits (66), Expect = 5.9
Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 11 LLGVNGAGKTSTFRMLTGDARVSDGDALVHGHSVRA-HVQDVHRLIGYCPQFDALFDNLT 187
L+G +GAGK++ +++ +G V GH +R+ ++Q + IG Q LF
Sbjct: 453 LVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTI 512
Query: 188 A 190
A
Sbjct: 513 A 513
>AB014533-1|BAA31608.1| 1316|Homo sapiens KIAA0633 protein protein.
Length = 1316
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/49 (32%), Positives = 22/49 (44%)
Frame = -1
Query: 461 PPPTALLMPRHTSRFDAGSMPVVGSSRKTNDEALNKATAVLIFLFVPAL 315
PP AL PR SRF G++ +R+ +A+ T VP L
Sbjct: 1267 PPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLL 1315
>DQ996467-1|ABI97388.1| 655|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 2 protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>BC125226-1|AAI25227.1| 639|Homo sapiens FGD6 protein protein.
Length = 639
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/44 (34%), Positives = 20/44 (45%)
Frame = +3
Query: 75 CRTATRSCTDTRCEHMCRTCTASLVIAPSSTHYSITLLRERPSR 206
C T T T H CR C + A SS Y + L+ +P+R
Sbjct: 437 CMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPAR 480
>BC125225-1|AAI25226.1| 639|Homo sapiens FGD6 protein protein.
Length = 639
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/44 (34%), Positives = 20/44 (45%)
Frame = +3
Query: 75 CRTATRSCTDTRCEHMCRTCTASLVIAPSSTHYSITLLRERPSR 206
C T T T H CR C + A SS Y + L+ +P+R
Sbjct: 437 CMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPAR 480
>BC092408-1|AAH92408.1| 611|Homo sapiens ABCG2 protein protein.
Length = 611
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>BC021281-1|AAH21281.1| 655|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 2 protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>BC013319-1|AAH13319.1| 376|Homo sapiens FGD6 protein protein.
Length = 376
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/44 (34%), Positives = 20/44 (45%)
Frame = +3
Query: 75 CRTATRSCTDTRCEHMCRTCTASLVIAPSSTHYSITLLRERPSR 206
C T T T H CR C + A SS Y + L+ +P+R
Sbjct: 230 CMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPAR 273
>AY333756-1|AAQ92942.1| 655|Homo sapiens ATP-binding cassette
sub-family G (WHITE) member 2 protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>AY333755-1|AAQ92941.1| 655|Homo sapiens mutant ATP-binding
cassette sub-family G (WHITE) member 2 protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>AY288307-1|AAP31310.1| 541|Homo sapiens ATP-binding cassette
sub-family G member 2 protein.
Length = 541
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 48 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 107
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 108 NAVLLLLKRMSKQGRT 123
>AY017168-1|AAG52982.1| 655|Homo sapiens ABC transporter ABCG2
protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>AK128492-1|BAC87464.1| 1053|Homo sapiens protein ( Homo sapiens
cDNA FLJ46642 fis, clone TRACH3003037, weakly similar
to Rho/Rac guanine nucleotide exchange factor. ).
Length = 1053
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/44 (34%), Positives = 20/44 (45%)
Frame = +3
Query: 75 CRTATRSCTDTRCEHMCRTCTASLVIAPSSTHYSITLLRERPSR 206
C T T T H CR C + A SS Y + L+ +P+R
Sbjct: 851 CMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPAR 894
>AK124904-1|BAC85990.1| 1430|Homo sapiens protein ( Homo sapiens cDNA
FLJ42914 fis, clone BRHIP3025161, weakly similar to
Rho/Rac guanine nucleotide exchange factor. ).
Length = 1430
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/44 (34%), Positives = 20/44 (45%)
Frame = +3
Query: 75 CRTATRSCTDTRCEHMCRTCTASLVIAPSSTHYSITLLRERPSR 206
C T T T H CR C + A SS Y + L+ +P+R
Sbjct: 1228 CMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPAR 1271
>AK002045-1|BAA92052.1| 432|Homo sapiens protein ( Homo sapiens
cDNA FLJ11183 fis, clone PLACE1007488, weakly similar to
PUTATIVE RHO/RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR. ).
Length = 432
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/44 (34%), Positives = 20/44 (45%)
Frame = +3
Query: 75 CRTATRSCTDTRCEHMCRTCTASLVIAPSSTHYSITLLRERPSR 206
C T T T H CR C + A SS Y + L+ +P+R
Sbjct: 230 CMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPAR 273
>AF463519-1|AAO14617.1| 655|Homo sapiens ATP-binding cassette
protein ABCG2 protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>AF098951-1|AAC97367.1| 655|Homo sapiens breast cancer resistance
protein protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>AC097484-1|AAY40902.1| 607|Homo sapiens unknown protein.
Length = 607
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>AB056867-1|BAB39212.1| 655|Homo sapiens Breast Cancer Resistance
Protein protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>AB051855-1|BAB46933.1| 655|Homo sapiens ATP-binding cassette
superfamily G (White) member 2 protein.
Length = 655
Score = 30.3 bits (65), Expect = 7.8
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Frame = +1
Query: 256 HRLAVELGFVVHYDKKV-----HECSAGTKRKISTXXXXXXXXXXXFLDEPTTGMDPASK 420
+R+ ELG D KV S G +++ S FLDEPTTG+D ++
Sbjct: 162 NRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTA 221
Query: 421 RLVWRGISSAVGGGRT 468
V + GRT
Sbjct: 222 NAVLLLLKRMSKQGRT 237
>AB037783-1|BAA92600.1| 699|Homo sapiens KIAA1362 protein protein.
Length = 699
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/44 (34%), Positives = 20/44 (45%)
Frame = +3
Query: 75 CRTATRSCTDTRCEHMCRTCTASLVIAPSSTHYSITLLRERPSR 206
C T T T H CR C + A SS Y + L+ +P+R
Sbjct: 560 CMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPAR 603
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,464,915
Number of Sequences: 237096
Number of extensions: 2287285
Number of successful extensions: 13089
Number of sequences better than 10.0: 127
Number of HSP's better than 10.0 without gapping: 12208
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13023
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9071127468
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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