Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV40412
(730 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 60 6e-09
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 60 6e-09
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 60 6e-09
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 60 6e-09
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 60 6e-09
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 60 6e-09
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 60 6e-09
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 60 6e-09
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 60 6e-09
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 60 6e-09
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 60 6e-09
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 60 6e-09
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 60 6e-09
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 60 6e-09
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 60 6e-09
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 60 6e-09
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 60 6e-09
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 60 6e-09
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 49 2e-05
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 49 2e-05
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 49 2e-05
DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant pu... 38 0.037
X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate activ... 34 0.45
AK074069-1|BAB84895.1| 579|Homo sapiens FLJ00140 protein protein. 31 4.2
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 97 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 156
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 157 PVLIEILVEVMDPSFVC 173
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 7 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 66
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 67 SILLEEVSPELVC 79
Score = 56.8 bits (131), Expect = 7e-08
Identities = 21/63 (33%), Positives = 42/63 (66%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECIDFVDTYSSQLVEMLVA 494
C +C F V+++ ++ NN++E+ I A D +C++L + L EC + VDTY S ++ +L+
Sbjct: 12 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 71
Query: 495 DMN 503
+++
Sbjct: 72 EVS 74
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 402 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 461
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 462 PVLIEILVEVMDPSFVC 478
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 312 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 371
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 372 SILLEEVSPELVC 384
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 302 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 361
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 362 VVDTYGSSILSILLEEVS 379
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 403 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 462
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 463 PVLIEILVEVMDPSFVC 479
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 313 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 372
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 373 SILLEEVSPELVC 385
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 303 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 362
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 363 VVDTYGSSILSILLEEVS 380
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 403 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 462
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 463 PVLIEILVEVMDPSFVC 479
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 313 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 372
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 373 SILLEEVSPELVC 385
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 303 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 362
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 363 VVDTYGSSILSILLEEVS 380
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 31.1 bits (67), Expect = 4.2
Identities = 13/43 (30%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALL--VQEIDPASVC 246
V+E CD L + CK +++QY I ++ +Q+ P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEIC 268
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 56.4 bits (130), Expect = 1e-07
Identities = 24/78 (30%), Positives = 49/78 (62%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S + +L+ +++
Sbjct: 360 VVDTYGSSIPSILLEEVS 377
Score = 56.0 bits (129), Expect = 1e-07
Identities = 22/73 (30%), Positives = 43/73 (58%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIP 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 116 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 175
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 176 PVLIEILVEVMDPSFVC 192
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 400 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 459
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 460 PVLIEILVEVMDPSFVC 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 369
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 370 SILLEEVSPELVC 382
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 300 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 359
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 360 VVDTYGSSILSILLEEVS 377
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 123 GEMSRPGEVCS 133
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 123 GEMSRPGEVC 132
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/41 (29%), Positives = 22/41 (53%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALLVQEIDPASVC 246
V+E CD L + CK +++QY I +++ + P +C
Sbjct: 226 VKEECDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEIC 265
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 60.5 bits (140), Expect = 6e-09
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +1
Query: 16 VAAPQSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYG 195
V P+ C C+ + YL L T+ ++ AA+++ C LPD +C +FV +Y
Sbjct: 406 VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYE 465
Query: 196 SAVIALLVQEIDPASVC 246
+I +LV+ +DP+ VC
Sbjct: 466 PVLIEILVEVMDPSFVC 482
Score = 58.0 bits (134), Expect = 3e-08
Identities = 22/73 (30%), Positives = 44/73 (60%)
Frame = +1
Query: 28 QSKAACAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVI 207
+S C C++ + + + + +TE ++ A + C LP +L+ EC+E V YGS+++
Sbjct: 316 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 375
Query: 208 ALLVQEIDPASVC 246
++L++E+ P VC
Sbjct: 376 SILLEEVSPELVC 388
Score = 57.6 bits (133), Expect = 4e-08
Identities = 24/78 (30%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 EEIRRVDVNSEKS-NCPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECID 449
E I++ +V ++ C +C F V+++ ++ NN++E+ I A D +C++L + L EC +
Sbjct: 306 EPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQE 365
Query: 450 FVDTYSSQLVEMLVADMN 503
VDTY S ++ +L+ +++
Sbjct: 366 VVDTYGSSILSILLEEVS 383
Score = 38.7 bits (86), Expect = 0.021
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQ-KLQSECIDFVDTYSSQLVEMLV 491
C +C V +LK+N +EE I L+ C L + + + C + VD+Y +++++
Sbjct: 66 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 125
Query: 492 ADMNAKRSACS 524
+M+ CS
Sbjct: 126 GEMSRPGEVCS 136
Score = 37.9 bits (84), Expect = 0.037
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 66 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 125
Query: 220 QEID-PASVC 246
E+ P VC
Sbjct: 126 GEMSRPGEVC 135
Score = 31.1 bits (67), Expect = 4.2
Identities = 13/43 (30%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Frame = +1
Query: 124 VQEACDVLPDALNGECKEFVTQYGSAVIALL--VQEIDPASVC 246
V+E CD L + CK +++QY I ++ +Q+ P +C
Sbjct: 229 VKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEIC 271
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 48.8 bits (111), Expect = 2e-05
Identities = 22/58 (37%), Positives = 36/58 (62%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECIDFVDTYSSQLVEML 488
C +C+ V++L+ L +N SE I AL+ +C+ + + ECI VDTYS LV+++
Sbjct: 294 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLV 351
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/68 (32%), Positives = 31/68 (45%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVIALLVQ 222
C C+ L L T+ + A + C +LP +CK FVTQY +I L
Sbjct: 396 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 455
Query: 223 EIDPASVC 246
+DP +VC
Sbjct: 456 MMDPVAVC 463
Score = 36.7 bits (81), Expect = 0.085
Identities = 19/68 (27%), Positives = 31/68 (45%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVIALLVQ 222
C C + L L +E + A++ C V+P ++ EC V Y +++ LV
Sbjct: 294 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVA 352
Query: 223 EIDPASVC 246
+I P VC
Sbjct: 353 KITPEKVC 360
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 48.8 bits (111), Expect = 2e-05
Identities = 22/58 (37%), Positives = 36/58 (62%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECIDFVDTYSSQLVEML 488
C +C+ V++L+ L +N SE I AL+ +C+ + + ECI VDTYS LV+++
Sbjct: 316 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLV 373
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/68 (32%), Positives = 31/68 (45%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVIALLVQ 222
C C+ L L T+ + A + C +LP +CK FVTQY +I L
Sbjct: 418 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 477
Query: 223 EIDPASVC 246
+DP +VC
Sbjct: 478 MMDPVAVC 485
Score = 36.7 bits (81), Expect = 0.085
Identities = 19/68 (27%), Positives = 31/68 (45%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVIALLVQ 222
C C + L L +E + A++ C V+P ++ EC V Y +++ LV
Sbjct: 316 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVA 374
Query: 223 EIDPASVC 246
+I P VC
Sbjct: 375 KITPEKVC 382
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 48.8 bits (111), Expect = 2e-05
Identities = 22/58 (37%), Positives = 36/58 (62%)
Frame = +3
Query: 315 CPLCLFAVEQLESVLKNNRSEENIRKALDGLCTRLSQKLQSECIDFVDTYSSQLVEML 488
C +C+ V++L+ L +N SE I AL+ +C+ + + ECI VDTYS LV+++
Sbjct: 26 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLV 83
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/68 (32%), Positives = 31/68 (45%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVIALLVQ 222
C C+ L L T+ + A + C +LP +CK FVTQY +I L
Sbjct: 128 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 187
Query: 223 EIDPASVC 246
+DP +VC
Sbjct: 188 MMDPVAVC 195
Score = 36.7 bits (81), Expect = 0.085
Identities = 19/68 (27%), Positives = 31/68 (45%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDALNGECKEFVTQYGSAVIALLVQ 222
C C + L L +E + A++ C V+P ++ EC V Y +++ LV
Sbjct: 26 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVA 84
Query: 223 EIDPASVC 246
+I P VC
Sbjct: 85 KITPEKVC 92
>DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant
pulmonary-associated protein B protein.
Length = 147
Score = 37.9 bits (84), Expect = 0.037
Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLP-DALNGECKEFVTQYGSAVIALLV 219
C C+ +H L + +D ++ +++ C+VLP L +C + + Y VI
Sbjct: 65 CQECEDIVHILNKMAKEAIFQDTMREFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQ 124
Query: 220 QEIDPASVC 246
+ID S+C
Sbjct: 125 NQIDSNSIC 133
>X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate
activator protein.
Length = 67
Score = 34.3 bits (75), Expect = 0.45
Identities = 16/63 (25%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +1
Query: 43 CAFCQYFLHYLQVQLSDTRTEDKVKAAVQEACDVLPDA-LNGECKEFVTQYGSAVIALLV 219
C C+ + L D TE+++ +++ CD LP ++ CKE V Y ++ ++
Sbjct: 5 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 64
Query: 220 QEI 228
E+
Sbjct: 65 GEM 67
>AK074069-1|BAB84895.1| 579|Homo sapiens FLJ00140 protein protein.
Length = 579
Score = 31.1 bits (67), Expect = 4.2
Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
Frame = +2
Query: 425 ETAERVHRLRGHVLESARRDAGGRHER----EEICVFLKLCRDQLHDPLKLTHS 574
+ A+R+ R+RG VL+ + D+G R +C+FL QL K T S
Sbjct: 485 QAAQRLERVRGRVLKKFKSDSGLAQRRFIRGWGLCIFLPFVLSQLEPGCKKTES 538
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,111,621
Number of Sequences: 237096
Number of extensions: 1990105
Number of successful extensions: 6162
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 5728
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6162
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8623170556
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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