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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdV40162
         (658 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A7TZ65 Cluster: Protein disulfide-isomerase 2; n=1; Lep...    63   5e-09
UniRef50_Q8IG53 Cluster: Protein disulfide isomerase protein 2, ...    61   2e-08
UniRef50_P07237 Cluster: Protein disulfide-isomerase precursor; ...    57   4e-07
UniRef50_Q26593 Cluster: Protein disulfide isomerase homologue p...    56   7e-07
UniRef50_O76945 Cluster: Protein disulphide isomerase; n=2; Dige...    52   2e-05
UniRef50_Q7XZ51 Cluster: Protein disulfide isomerase 1; n=1; Gri...    46   0.001
UniRef50_Q17967 Cluster: Protein disulfide-isomerase 1 precursor...    45   0.001
UniRef50_Q54EN4 Cluster: Protein disulfide isomerase; n=1; Dicty...    45   0.002
UniRef50_Q6DH89 Cluster: Proteasome (Prosome, macropain) subunit...    44   0.002
UniRef50_Q5YER4 Cluster: Protein disulfide isomerase; n=1; Bigel...    44   0.002
UniRef50_Q6C781 Cluster: Similar to sp|P55059 Humicola insolens ...    44   0.003
UniRef50_Q7YY73 Cluster: Protein disulphide isomerase, probable;...    44   0.004
UniRef50_Q5K7H6 Cluster: Putative uncharacterized protein; n=1; ...    44   0.004
UniRef50_UPI0000E49F35 Cluster: PREDICTED: similar to Thioredoxi...    42   0.010
UniRef50_Q4SZH7 Cluster: Chromosome 18 SCAF11624, whole genome s...    42   0.010
UniRef50_A7STM8 Cluster: Predicted protein; n=2; Nematostella ve...    42   0.010
UniRef50_UPI0000D55597 Cluster: PREDICTED: similar to CG1837-PA;...    42   0.017
UniRef50_Q2HPL0 Cluster: Putative disulphide isomerase; n=1; Sol...    42   0.017
UniRef50_A7RMG9 Cluster: Predicted protein; n=1; Nematostella ve...    42   0.017
UniRef50_O13811 Cluster: Protein disulfide-isomerase C17H9.14c p...    41   0.023
UniRef50_Q4Q9C8 Cluster: Protein disulfide isomerase, putative; ...    41   0.030
UniRef50_Q9LRF6 Cluster: Thioredoxin; n=1; Chlorella vulgaris|Re...    40   0.040
UniRef50_Q16961 Cluster: Disulfide-like protein; n=1; Acanthamoe...    40   0.053
UniRef50_A0D729 Cluster: Chromosome undetermined scaffold_4, who...    40   0.069
UniRef50_Q10057 Cluster: Putative protein disulfide-isomerase C1...    40   0.069
UniRef50_Q8I8E1 Cluster: Disulfide isomerase PDI; n=4; Leishmani...    39   0.092
UniRef50_A7SNX3 Cluster: Predicted protein; n=1; Nematostella ve...    39   0.092
UniRef50_Q9TWZ1 Cluster: Protein disulphide isomerase isoform/mu...    39   0.12 
UniRef50_O48949 Cluster: Protein disulfide isomerase RB60; n=2; ...    38   0.16 
UniRef50_Q7QEL4 Cluster: ENSANGP00000017364; n=5; Endopterygota|...    38   0.16 
UniRef50_Q5YBC2 Cluster: Plastid protein disulfide isomerase; n=...    38   0.21 
UniRef50_O76191 Cluster: Transglutaminase precursor; n=11; Bilat...    38   0.21 
UniRef50_O15735 Cluster: Protein disulfide isomerase precursor; ...    38   0.21 
UniRef50_A7TEH6 Cluster: Putative uncharacterized protein; n=1; ...    38   0.21 
UniRef50_Q6V4H6 Cluster: Pancreas-specific protein disulfide iso...    38   0.28 
UniRef50_Q57WS0 Cluster: Protein disulfide isomerase, putative; ...    38   0.28 
UniRef50_Q6CC54 Cluster: Similar to DEHA0F19404g Debaryomyces ha...    38   0.28 
UniRef50_A6RP52 Cluster: Putative uncharacterized protein; n=1; ...    38   0.28 
UniRef50_Q00248 Cluster: Protein disulfide-isomerase precursor; ...    38   0.28 
UniRef50_Q01AS5 Cluster: Thioredoxin/protein disulfide isomerase...    37   0.37 
UniRef50_Q4E3F7 Cluster: Protein disulfide isomerase, putative; ...    37   0.37 
UniRef50_Q9C1Z8 Cluster: Protein disulphide isomerase; n=1; Pich...    37   0.37 
UniRef50_Q8IQL9 Cluster: CG6988-PB, isoform B; n=1; Drosophila m...    37   0.49 
UniRef50_Q96VF3 Cluster: Putative uncharacterized protein; n=3; ...    37   0.49 
UniRef50_Q8NBS9 Cluster: Thioredoxin domain-containing protein 5...    37   0.49 
UniRef50_A2EFV6 Cluster: Thioredoxin family protein; n=1; Tricho...    36   0.65 
UniRef50_A2EE81 Cluster: Thioredoxin family protein; n=1; Tricho...    36   0.65 
UniRef50_Q4PDL1 Cluster: Putative uncharacterized protein; n=1; ...    36   0.65 
UniRef50_O22263 Cluster: Probable protein disulfide-isomerase A6...    36   0.65 
UniRef50_Q92249 Cluster: Protein disulfide-isomerase erp38 precu...    36   0.65 
UniRef50_A5C1Q6 Cluster: Putative uncharacterized protein; n=1; ...    36   0.86 
UniRef50_Q4UG82 Cluster: Protein disulfide isomerase, putative; ...    36   0.86 
UniRef50_Q9SRG3 Cluster: Protein disulfide-isomerase 2 precursor...    36   0.86 
UniRef50_Q5CXJ5 Cluster: Thioredoxin; protein disulfide isomeras...    36   1.1  
UniRef50_UPI0000498890 Cluster: protein disulfide isomerase; n=2...    35   1.5  
UniRef50_Q9FF55 Cluster: Protein disulphide isomerase-like prote...    35   1.5  
UniRef50_Q9GRI2 Cluster: Protein disulfide isomerase precursor; ...    35   1.5  
UniRef50_Q6BKX9 Cluster: Debaryomyces hansenii chromosome F of s...    35   1.5  
UniRef50_Q5A5F2 Cluster: Likely protein disulfide isomerase; n=5...    35   1.5  
UniRef50_P30101 Cluster: Protein disulfide-isomerase A3 precurso...    35   1.5  
UniRef50_Q8H703 Cluster: Protein disulfide-isomerase; n=1; Phyto...    35   2.0  
UniRef50_Q2GVJ5 Cluster: Putative uncharacterized protein; n=1; ...    35   2.0  
UniRef50_A1DGY3 Cluster: Disulfide isomerase, putative; n=10; Pe...    35   2.0  
UniRef50_UPI0000ECAAC5 Cluster: protein disulfide isomerase-like...    34   2.6  
UniRef50_Q869Q9 Cluster: Similar to Acanthamoeba castellanii (Am...    34   2.6  
UniRef50_Q5XWD1 Cluster: Protein disulfide isomerase; n=2; Entam...    34   2.6  
UniRef50_A7AV78 Cluster: Protein disulfide-isomerase, putative; ...    34   2.6  
UniRef50_A0BSE8 Cluster: Chromosome undetermined scaffold_125, w...    34   2.6  
UniRef50_Q8LSK4 Cluster: Protein disulfide isomerase-like PDI-H;...    34   3.5  
UniRef50_Q24I64 Cluster: Thioredoxin family protein; n=1; Tetrah...    34   3.5  
UniRef50_A7SIZ4 Cluster: Predicted protein; n=3; Nematostella ve...    34   3.5  
UniRef50_A0EAP3 Cluster: Chromosome undetermined scaffold_86, wh...    34   3.5  
UniRef50_A0CHN0 Cluster: Chromosome undetermined scaffold_182, w...    34   3.5  
UniRef50_Q5KQ34 Cluster: Disulfide-isomerase, putative; n=1; Fil...    34   3.5  
UniRef50_P17967 Cluster: Protein disulfide-isomerase precursor; ...    34   3.5  
UniRef50_Q00002 Cluster: Protein disulfide-isomerase; n=1; Alter...    34   3.5  
UniRef50_A3B992 Cluster: Putative uncharacterized protein; n=2; ...    33   4.6  
UniRef50_Q582J4 Cluster: Protein disulfide isomerase, putative; ...    33   4.6  
UniRef50_Q5AKR3 Cluster: Potential thioredoxin; n=3; Saccharomyc...    33   4.6  
UniRef50_P13667 Cluster: Protein disulfide-isomerase A4 precurso...    33   4.6  
UniRef50_Q13087 Cluster: Protein disulfide-isomerase A2 precurso...    33   4.6  
UniRef50_P12865 Cluster: Bloodstream-specific protein 2 precurso...    33   4.6  
UniRef50_Q55FU1 Cluster: Putative uncharacterized protein; n=1; ...    33   6.0  
UniRef50_Q54BW3 Cluster: Putative uncharacterized protein; n=1; ...    33   6.0  
UniRef50_A3LVR0 Cluster: Predicted protein; n=3; Saccharomycetac...    33   6.0  
UniRef50_UPI00015B4150 Cluster: PREDICTED: similar to protein di...    33   8.0  
UniRef50_UPI0000D57458 Cluster: PREDICTED: similar to CG8983-PA,...    33   8.0  
UniRef50_A0DI01 Cluster: Chromosome undetermined scaffold_51, wh...    33   8.0  
UniRef50_A0D787 Cluster: Chromosome undetermined scaffold_4, who...    33   8.0  
UniRef50_Q6FPP9 Cluster: Similar to sp|P40557 Saccharomyces cere...    33   8.0  
UniRef50_O51088 Cluster: Thioredoxin; n=6; Borrelia burgdorferi ...    33   8.0  

>UniRef50_A7TZ65 Cluster: Protein disulfide-isomerase 2; n=1;
           Lepeophtheirus salmonis|Rep: Protein disulfide-isomerase
           2 - Lepeophtheirus salmonis (salmon louse)
          Length = 401

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 29/44 (65%), Positives = 35/44 (79%), Gaps = 1/44 (2%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLYSK-DNQVHDYNGERTLAGLTKFVETDG 410
           NELE  K+T FPTIKL+ K  N+V +YNGERTL G TKF+E+DG
Sbjct: 331 NELESIKVTGFPTIKLFKKGSNEVVNYNGERTLEGFTKFLESDG 374



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 15/28 (53%), Positives = 24/28 (85%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCKQLVPI+++LG++F + +D+ + K
Sbjct: 298 CGHCKQLVPIWEELGKNFADKEDIVIAK 325


>UniRef50_Q8IG53 Cluster: Protein disulfide isomerase protein 2,
           isoform b; n=2; Caenorhabditis elegans|Rep: Protein
           disulfide isomerase protein 2, isoform b -
           Caenorhabditis elegans
          Length = 437

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 31/68 (45%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLY-SKDNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEE 458
           NE+E  KI SFPTIK + +  N+V DY G+RT+ G TKF+ET+G+         + EEE 
Sbjct: 370 NEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFLETNGKEGAGASEEEKAEEEA 429

Query: 459 DVPARDEL 482
           D     EL
Sbjct: 430 DEEGHTEL 437



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 16/28 (57%), Positives = 21/28 (75%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCKQL P +DKLGE F +D+ + + K
Sbjct: 337 CGHCKQLAPTWDKLGEKFADDESIVIAK 364


>UniRef50_P07237 Cluster: Protein disulfide-isomerase precursor;
           n=84; Eukaryota|Rep: Protein disulfide-isomerase
           precursor - Homo sapiens (Human)
          Length = 508

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 30/63 (47%), Positives = 40/63 (63%), Gaps = 3/63 (4%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLY--SKDNQVHDYNGERTLAGLTKFVETDG-EGAEPVPSVTEFEE 452
           NE+E  K+ SFPT+K +  S D  V DYNGERTL G  KF+E+ G +GA     + + EE
Sbjct: 430 NEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEE 489

Query: 453 EED 461
            E+
Sbjct: 490 AEE 492



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 19/36 (52%), Positives = 27/36 (75%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV FY   CGHCKQL PI+DKLGE +++ +++ + K
Sbjct: 389 FVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAK 424


>UniRef50_Q26593 Cluster: Protein disulfide isomerase homologue
           precursor; n=2; Schistosoma|Rep: Protein disulfide
           isomerase homologue precursor - Schistosoma mansoni
           (Blood fluke)
          Length = 482

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 25/59 (42%), Positives = 39/59 (66%), Gaps = 1/59 (1%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLYSKDN-QVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEE 455
           NE+E  K+TSFPT+K Y K++ +V DY G+R+   L KFVE+ G+ +E      + ++E
Sbjct: 423 NEVEDLKVTSFPTLKFYPKNSEEVIDYTGDRSFEALKKFVESGGKSSEATKQEDQIKDE 481



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 18/32 (56%), Positives = 22/32 (68%), Gaps = 2/32 (6%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDV 255
           FV  Y   CGHCK L P++D+LGE F+N D V
Sbjct: 383 FVKLYAPWCGHCKALAPVWDELGETFKNSDTV 414


>UniRef50_O76945 Cluster: Protein disulphide isomerase; n=2;
           Digenea|Rep: Protein disulphide isomerase - Fasciola
           hepatica (Liver fluke)
          Length = 489

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 25/59 (42%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLYSK-DNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEE 455
           NE E   + SFPT+K Y K  ++  +Y GERTL  L +FV+++G+GA+   +  E  EE
Sbjct: 430 NEAEGLSVQSFPTLKYYPKGSSEPIEYTGERTLEALKRFVDSEGKGAQKEETEAEPHEE 488



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCKQL PI+D+LGE ++  +D+ + K
Sbjct: 397 CGHCKQLAPIWDELGEAYKTKEDLIIAK 424


>UniRef50_Q7XZ51 Cluster: Protein disulfide isomerase 1; n=1;
           Griffithsia japonica|Rep: Protein disulfide isomerase 1
           - Griffithsia japonica (Red alga)
          Length = 235

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 25/58 (43%), Positives = 33/58 (56%)
 Frame = +3

Query: 291 EHTKITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEEDV 464
           E  +I  FPT+KL+SK   + DY G RT   L K++E        +PSV E E+EE V
Sbjct: 86  EKYEIRGFPTLKLFSKGELISDYKGGRTKDALIKYIE-----RAMLPSVVECEDEEAV 138


>UniRef50_Q17967 Cluster: Protein disulfide-isomerase 1 precursor;
           n=2; Caenorhabditis|Rep: Protein disulfide-isomerase 1
           precursor - Caenorhabditis elegans
          Length = 485

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 19/36 (52%), Positives = 27/36 (75%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV FY   CGHCKQLVP++D+L E +E++ +V + K
Sbjct: 385 FVKFYAPWCGHCKQLVPVWDELAEKYESNPNVVIAK 420



 Score = 37.9 bits (84), Expect = 0.21
 Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLYSKDNQVH-DYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEE 455
           NEL   K+ SFPT+KL+   +    DY+G+R L    +FV      A    + ++  EE
Sbjct: 426 NELADVKVNSFPTLKLWPAGSSTPVDYDGDRNLEKFEEFVNKYAGSASESETASQDHEE 484


>UniRef50_Q54EN4 Cluster: Protein disulfide isomerase; n=1;
           Dictyostelium discoideum AX4|Rep: Protein disulfide
           isomerase - Dictyostelium discoideum AX4
          Length = 513

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 17/28 (60%), Positives = 22/28 (78%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L PIYDKLGE+ ++ + VS+ K
Sbjct: 406 CGHCKNLAPIYDKLGEYLKDVESVSIVK 433


>UniRef50_Q6DH89 Cluster: Proteasome (Prosome, macropain) subunit,
           beta type, 3; n=3; Euteleostomi|Rep: Proteasome
           (Prosome, macropain) subunit, beta type, 3 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 338

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 19/36 (52%), Positives = 27/36 (75%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV FY   CGHCKQL PI+D+LGE F+++ ++ + K
Sbjct: 263 FVEFYAPWCGHCKQLAPIWDQLGEKFKDNANIVVAK 298



 Score = 39.5 bits (88), Expect = 0.069
 Identities = 18/34 (52%), Positives = 24/34 (70%), Gaps = 2/34 (5%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLY--SKDNQVHDYNGERTL 377
           NE+E  K+ SFPT+K +    + +V DYNGERTL
Sbjct: 304 NEIEAVKVHSFPTLKFFPAGDERKVIDYNGERTL 337


>UniRef50_Q5YER4 Cluster: Protein disulfide isomerase; n=1;
           Bigelowiella natans|Rep: Protein disulfide isomerase -
           Bigelowiella natans (Pedinomonas minutissima)
           (Chlorarachnion sp.(strain CCMP 621))
          Length = 457

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK+L P YDKLG H+++D ++ + K
Sbjct: 367 CGHCKKLAPTYDKLGAHYKDDANIVIAK 394


>UniRef50_Q6C781 Cluster: Similar to sp|P55059 Humicola insolens
           Protein disulfide isomerase; n=1; Yarrowia
           lipolytica|Rep: Similar to sp|P55059 Humicola insolens
           Protein disulfide isomerase - Yarrowia lipolytica
           (Candida lipolytica)
          Length = 504

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/67 (40%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLY--SKDNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEE 455
           NE     +  FPTIKLY   K N    Y G RTL GL +F++    G   V  +   +EE
Sbjct: 428 NEFPDEDVKGFPTIKLYPAGKKNAPITYPGARTLEGLNQFIKE--HGTHKVDGLAHADEE 485

Query: 456 EDVPARD 476
           E  PA+D
Sbjct: 486 E-APAKD 491



 Score = 37.5 bits (83), Expect = 0.28
 Identities = 14/25 (56%), Positives = 19/25 (76%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVS 258
           CGHCK L PIYD+LG+ F +  ++S
Sbjct: 391 CGHCKILAPIYDELGDLFFDHPEIS 415


>UniRef50_Q7YY73 Cluster: Protein disulphide isomerase, probable;
           n=4; Cryptosporidium|Rep: Protein disulphide isomerase,
           probable - Cryptosporidium parvum
          Length = 481

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 20/48 (41%), Positives = 30/48 (62%), Gaps = 4/48 (8%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPKSTPP----PTNWNTPRSRPS 315
           CGHCK L PIY++LGE ++++D V + K   P    P    +PR+ P+
Sbjct: 391 CGHCKNLEPIYNQLGEEYKDNDKVVIAKINGPQNDIPYEGFSPRAFPT 438


>UniRef50_Q5K7H6 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 492

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 22/62 (35%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
 Frame = +3

Query: 300 KITSFPTIKLY-SKDNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEEDVPARD 476
           ++  FPT+K   +  ++  DY G+R+L  L +FVET+ +    V +  E+E+E++ P  D
Sbjct: 432 RVQGFPTLKFRPAGSSEFIDYTGDRSLDSLVEFVETNRKSDADV-AEEEWEDEDETPEHD 490

Query: 477 EL 482
           EL
Sbjct: 491 EL 492



 Score = 37.1 bits (82), Expect = 0.37
 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPKSTPPPTNWNTPRSRPSQRSNF 330
           F  FY   CGHC++L PI+D LGE +  ++++ + +     T  + P S P +   F
Sbjct: 382 FAEFYAPWCGHCQRLAPIWDTLGEKYAGNNNIIIAQM--DATENDIPPSAPFRVQGF 436


>UniRef50_UPI0000E49F35 Cluster: PREDICTED: similar to Thioredoxin
           domain-containing protein 5 precursor (Thioredoxin-like
           protein p46) (Endoplasmic reticulum protein ERp46)
           (Plasma cell-specific thioredoxin-related protein)
           (PC-TRP); n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to Thioredoxin domain-containing
           protein 5 precursor (Thioredoxin-like protein p46)
           (Endoplasmic reticulum protein ERp46) (Plasma
           cell-specific thioredoxin-related protein) (PC-TRP) -
           Strongylocentrotus purpuratus
          Length = 685

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 17/37 (45%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
 Frame = +1

Query: 163 HFVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           HF+ FY   CGHCK+L P +D L + F++ D V++ K
Sbjct: 453 HFIKFYAPWCGHCKRLAPTWDDLAKGFQHSDIVTIAK 489



 Score = 37.9 bits (84), Expect = 0.21
 Identities = 16/35 (45%), Positives = 25/35 (71%), Gaps = 2/35 (5%)
 Frame = +1

Query: 169 VLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           V FY   C HC++LVP++D+L E F++  DV++ K
Sbjct: 594 VKFYAPWCPHCQKLVPVWDELAEKFDSRKDVTIGK 628



 Score = 37.5 bits (83), Expect = 0.28
 Identities = 14/33 (42%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
 Frame = +1

Query: 160 EHFVLFYR--CGHCKQLVPIYDKLGEHFENDDD 252
           +HFV F+   CGHC++L PI+ +L E +   +D
Sbjct: 330 DHFVKFFAPWCGHCQRLAPIWSQLSEKYNKPED 362



 Score = 37.5 bits (83), Expect = 0.28
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETDGEGAE-PVPSV 437
           +T +PT+KLY KD +   Y G+R  A L  ++E +    E  VP V
Sbjct: 384 VTGYPTLKLYKKDKEPLKYKGKRDFATLDAYIEKELNPQEADVPQV 429



 Score = 35.9 bits (79), Expect = 0.86
 Identities = 17/59 (28%), Positives = 28/59 (47%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEEDVPARDE 479
           +  +PT+K ++    V  Y G R    + ++V    +GAE  P     E  + VP R+E
Sbjct: 504 VKGYPTLKFFTDGEAVESYKGGRDHVAMKEYVSKMTKGAEAAPLPGSEEAIKVVPVREE 562


>UniRef50_Q4SZH7 Cluster: Chromosome 18 SCAF11624, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 18
           SCAF11624, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 552

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV FY   CGHCK+L P ++KL E F + DD+ + K
Sbjct: 433 FVEFYAPWCGHCKELAPTWEKLAEKFADRDDIIIAK 468



 Score = 40.3 bits (90), Expect = 0.040
 Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLYSK-DNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEE 458
           NE++  +I  FPT+K +   +  V DY G+R L  L+KF+  D  G  P  S TE EE+ 
Sbjct: 474 NEVDSLEIKGFPTLKYFPLGERYVVDYTGKRDLETLSKFL--DNGGVLPEES-TEEEEDN 530

Query: 459 DVPARDE 479
           D    D+
Sbjct: 531 DEDDDDD 537


>UniRef50_A7STM8 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 646

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 15/28 (53%), Positives = 20/28 (71%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L P + KLG+HF ND ++ + K
Sbjct: 555 CGHCKALEPTFKKLGKHFRNDKNIVIAK 582



 Score = 33.9 bits (74), Expect = 3.5
 Identities = 11/22 (50%), Positives = 15/22 (68%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDD 249
           CGHCKQL P Y+K  +  + +D
Sbjct: 205 CGHCKQLAPEYEKAAQELQKND 226


>UniRef50_UPI0000D55597 Cluster: PREDICTED: similar to CG1837-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG1837-PA - Tribolium castaneum
          Length = 382

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 15/38 (39%), Positives = 26/38 (68%), Gaps = 2/38 (5%)
 Frame = +1

Query: 160 EHFVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           +HF+ FY   CGHC++L P++++L +  E D  +S+ K
Sbjct: 166 KHFIKFYAPWCGHCQKLAPVWEQLAKSLEFDSSISIAK 203



 Score = 40.3 bits (90), Expect = 0.040
 Identities = 17/36 (47%), Positives = 25/36 (69%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV F+   CGHCK+L P +D+LG+ F  D +V++ K
Sbjct: 290 FVKFFAPWCGHCKRLAPTWDELGKKFVADSNVNIAK 325



 Score = 37.9 bits (84), Expect = 0.21
 Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
 Frame = +1

Query: 163 HFVLFYR--CGHCKQLVPIYDKLGEHFENDD 249
           HFV+FY   CGHC++L P +++L E    DD
Sbjct: 43  HFVMFYAPWCGHCQRLGPTWEQLAEMLNEDD 73



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 14/34 (41%), Positives = 23/34 (67%)
 Frame = +3

Query: 300 KITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVE 401
           ++  FPTI LY   +++ +Y+G RTL  L +FV+
Sbjct: 341 EVEGFPTIFLYKNGDKISEYSGSRTLEDLYEFVK 374


>UniRef50_Q2HPL0 Cluster: Putative disulphide isomerase; n=1;
           Solanum tuberosum|Rep: Putative disulphide isomerase -
           Solanum tuberosum (Potato)
          Length = 250

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 15/28 (53%), Positives = 21/28 (75%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCKQL P Y+++G  FE +D+V + K
Sbjct: 147 CGHCKQLAPTYEEVGAIFEGEDNVLIAK 174


>UniRef50_A7RMG9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 363

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 14/28 (50%), Positives = 21/28 (75%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L P+Y+K+GE F+N+ +  + K
Sbjct: 170 CGHCKNLAPVYEKVGEAFKNEPNCVIAK 197



 Score = 40.7 bits (91), Expect = 0.030
 Identities = 15/28 (53%), Positives = 19/28 (67%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCKQL P Y++LGE +    DV + K
Sbjct: 51  CGHCKQLAPTYEQLGEAYTQSSDVIIAK 78


>UniRef50_O13811 Cluster: Protein disulfide-isomerase C17H9.14c
           precursor; n=1; Schizosaccharomyces pombe|Rep: Protein
           disulfide-isomerase C17H9.14c precursor -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 359

 Score = 41.1 bits (92), Expect = 0.023
 Identities = 15/28 (53%), Positives = 21/28 (75%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L P+Y++LG  FE+ +DV + K
Sbjct: 51  CGHCKSLAPVYEELGALFEDHNDVLIGK 78



 Score = 37.1 bits (82), Expect = 0.37
 Identities = 13/28 (46%), Positives = 21/28 (75%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CG+CK+L P Y+ LG+ F+N+ +V + K
Sbjct: 170 CGYCKRLAPTYETLGKVFKNEPNVEIVK 197



 Score = 34.3 bits (75), Expect = 2.6
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
 Frame = +3

Query: 300 KITSFPTIKLYSKDNQVHD--YNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEEDVPAR 473
           ++ SFPTIK + KD++     Y G+R+L  L +++     G +  P  T       +P  
Sbjct: 211 EVASFPTIKFFPKDDKDKPELYEGDRSLESLIEYINKK-SGTQRSPDGTLLSTAGRIPTF 269

Query: 474 DE 479
           DE
Sbjct: 270 DE 271


>UniRef50_Q4Q9C8 Cluster: Protein disulfide isomerase, putative;
           n=3; Leishmania|Rep: Protein disulfide isomerase,
           putative - Leishmania major
          Length = 377

 Score = 40.7 bits (91), Expect = 0.030
 Identities = 18/35 (51%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
 Frame = +1

Query: 169 VLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           V+FY   CGHCK L PIY+ L + F ND DV + +
Sbjct: 178 VMFYAPWCGHCKALKPIYNTLAKVFSNDKDVVIAR 212


>UniRef50_Q9LRF6 Cluster: Thioredoxin; n=1; Chlorella vulgaris|Rep:
           Thioredoxin - Chlorella vulgaris (Green alga)
          Length = 216

 Score = 40.3 bits (90), Expect = 0.040
 Identities = 14/28 (50%), Positives = 21/28 (75%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L PIY++LG  F +++ V++ K
Sbjct: 113 CGHCKSLAPIYEELGTKFADNESVTIAK 140


>UniRef50_Q16961 Cluster: Disulfide-like protein; n=1; Acanthamoeba
           castellanii|Rep: Disulfide-like protein - Acanthamoeba
           castellanii (Amoeba)
          Length = 406

 Score = 39.9 bits (89), Expect = 0.053
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETDGEGAEPVP---SVTEFEEEEDV 464
           +  +PTIKL  KDNQ++ Y G R +    +F E+  +  +PVP        EE EDV
Sbjct: 98  VKGYPTIKLL-KDNQLYAYKGARKVDDFLQFAESGYKAVDPVPVPAPAVVVEEAEDV 153


>UniRef50_A0D729 Cluster: Chromosome undetermined scaffold_4, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_4,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 188

 Score = 39.5 bits (88), Expect = 0.069
 Identities = 17/53 (32%), Positives = 32/53 (60%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEED 461
           I  +PT+ LY KDN+ H + G+RT   + KF++ D   ++ +  V ++E  ++
Sbjct: 85  IKGYPTL-LYVKDNKTHKFQGQRTPELIIKFIQEDYAQSKEISDVPKYEPYQE 136


>UniRef50_Q10057 Cluster: Putative protein disulfide-isomerase
           C1F5.02 precursor; n=1; Schizosaccharomyces pombe|Rep:
           Putative protein disulfide-isomerase C1F5.02 precursor -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 492

 Score = 39.5 bits (88), Expect = 0.069
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L P Y+KL E + +D +V + K
Sbjct: 385 CGHCKNLAPTYEKLAEEYSDDSNVVVAK 412



 Score = 34.3 bits (75), Expect = 2.6
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHD--YNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEEDVPARD 476
           I+ FPTI  +  +++V+   Y G+RTL  L+ F++      EP+      +E+E VPA D
Sbjct: 424 ISGFPTIMFFKANDKVNPVRYEGDRTLEDLSAFIDKHA-SFEPIK-----KEKESVPAPD 477


>UniRef50_Q8I8E1 Cluster: Disulfide isomerase PDI; n=4;
           Leishmania|Rep: Disulfide isomerase PDI - Leishmania
           major
          Length = 477

 Score = 39.1 bits (87), Expect = 0.092
 Identities = 15/29 (51%), Positives = 23/29 (79%), Gaps = 2/29 (6%)
 Frame = +1

Query: 169 VLFYR--CGHCKQLVPIYDKLGEHFENDD 249
           +LFY   CGHCK+L P+YDK+ + FE+++
Sbjct: 375 LLFYAPWCGHCKKLHPVYDKVAKSFESEN 403



 Score = 34.7 bits (76), Expect = 2.0
 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
 Frame = +3

Query: 291 EHTKITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETD-GEGAEPVPSVTEFEE 452
           E  +I  FPT+ ++    +V  Y+G RT AG+  +++   G   + + +  E EE
Sbjct: 84  EKYEIKGFPTLYIFRNGEKVKIYDGPRTAAGIASYMKAHVGPSMKAISTAEELEE 138


>UniRef50_A7SNX3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 359

 Score = 39.1 bits (87), Expect = 0.092
 Identities = 16/37 (43%), Positives = 26/37 (70%), Gaps = 2/37 (5%)
 Frame = +1

Query: 163 HFVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           HFV FY   C HC +L PI+++L E F+++ D+++ K
Sbjct: 129 HFVKFYAPWCIHCIKLAPIWERLAEDFKDNADITISK 165



 Score = 36.7 bits (81), Expect = 0.49
 Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 3/38 (7%)
 Frame = +1

Query: 163 HFVLFYR--CGHCKQLVPIYDKLGEHFENDD-DVSLPK 267
           HFV+FY   C HCK ++P ++ LGE +  +  D+++ K
Sbjct: 6   HFVMFYGPWCEHCKNMMPAWEALGEQYSKEKRDLTIAK 43



 Score = 33.9 bits (74), Expect = 3.5
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETD--GEGAEPVPSVTEFEEEEDVPARD 476
           +  FPT+KL+    +V  Y+G R+L  L  +V+      G     +  + E  E+VP  D
Sbjct: 180 VNGFPTLKLFKNGREVDRYSGMRSLEDLKNYVKLKIAEHGLLSTVTTDKSETAEEVPPTD 239


>UniRef50_Q9TWZ1 Cluster: Protein disulphide isomerase
           isoform/multifunctional endoplasmic reticulum luminal
           polypeptide; n=8; Endopterygota|Rep: Protein disulphide
           isomerase isoform/multifunctional endoplasmic reticulum
           luminal polypeptide - Drosophila melanogaster (Fruit
           fly)
          Length = 489

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 15/51 (29%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETD-GEGAEPVPSVTEFEE 452
           ++ +PT+K++ +D    DYNG R  +G+ K++    G  ++ V +V E ++
Sbjct: 95  VSGYPTLKIFRQDEVSQDYNGPRDSSGIAKYMRAQVGPASKTVRTVAELKK 145



 Score = 37.5 bits (83), Expect = 0.28
 Identities = 14/28 (50%), Positives = 22/28 (78%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK+L PIY++L +  + D+DV++ K
Sbjct: 394 CGHCKKLTPIYEELAQKLQ-DEDVAIVK 420



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 3/35 (8%)
 Frame = +1

Query: 154 QHEH-FVLFYR--CGHCKQLVPIYDKLGEHFENDD 249
           QHE   V+FY   CGHCK+L P Y K  E  ++DD
Sbjct: 38  QHETTLVMFYAPWCGHCKRLKPEYAKAAEIVKDDD 72


>UniRef50_O48949 Cluster: Protein disulfide isomerase RB60; n=2;
           Chlamydomonadales|Rep: Protein disulfide isomerase RB60
           - Chlamydomonas reinhardtii
          Length = 532

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 15/28 (53%), Positives = 19/28 (67%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK+L PIY KL + F+  D V + K
Sbjct: 423 CGHCKKLEPIYKKLAKRFKKVDSVIIAK 450


>UniRef50_Q7QEL4 Cluster: ENSANGP00000017364; n=5;
           Endopterygota|Rep: ENSANGP00000017364 - Anopheles
           gambiae str. PEST
          Length = 400

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 15/38 (39%), Positives = 24/38 (63%), Gaps = 2/38 (5%)
 Frame = +1

Query: 160 EHFVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           +HFV FY   CGHC +L P +++L    E++ D+ + K
Sbjct: 167 KHFVKFYAPWCGHCTKLAPTWEELARSLEHERDIRVSK 204


>UniRef50_Q5YBC2 Cluster: Plastid protein disulfide isomerase; n=2;
           Trebouxiophyceae|Rep: Plastid protein disulfide
           isomerase - Helicosporidium sp. subsp. Simulium jonesii
           (Green alga)
          Length = 240

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 15/24 (62%), Positives = 17/24 (70%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDV 255
           CGHCK+L PIY KL + FE  D V
Sbjct: 131 CGHCKKLEPIYAKLAKRFETVDSV 154


>UniRef50_O76191 Cluster: Transglutaminase precursor; n=11;
           Bilateria|Rep: Transglutaminase precursor - Dirofilaria
           immitis (Canine heartworm)
          Length = 497

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETD-GEGAEPVPSVTEFEE 452
           ++ FPT+K++ K     DY+G R   G+ K++    G  A  + +  EFE+
Sbjct: 99  VSGFPTLKIFRKGELAQDYDGPRVAEGIVKYMRGQAGPSATEINTQQEFEK 149



 Score = 35.1 bits (77), Expect = 1.5
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L P YD+LG+    +  V + K
Sbjct: 400 CGHCKALAPKYDELGQKLSGEPGVVIAK 427


>UniRef50_O15735 Cluster: Protein disulfide isomerase precursor;
           n=3; Dictyostelium discoideum|Rep: Protein disulfide
           isomerase precursor - Dictyostelium discoideum (Slime
           mold)
          Length = 363

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 14/28 (50%), Positives = 20/28 (71%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK+L+P Y+ LG  + N+ DV + K
Sbjct: 172 CGHCKKLMPDYEILGNTYANEKDVVIAK 199


>UniRef50_A7TEH6 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 277

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 13/27 (48%), Positives = 19/27 (70%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLP 264
           C HCK+L P++DKLGE ++ +    LP
Sbjct: 55  CSHCKRLAPVFDKLGEFYDKNIGNDLP 81


>UniRef50_Q6V4H6 Cluster: Pancreas-specific protein disulfide
           isomerase; n=6; Xenopus|Rep: Pancreas-specific protein
           disulfide isomerase - Xenopus laevis (African clawed
           frog)
          Length = 526

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 14/36 (38%), Positives = 26/36 (72%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV FY   C HCK++ P++++LGE +++ ++V + K
Sbjct: 412 FVEFYAPWCSHCKEMEPVWEELGEKYKDHENVIIAK 447


>UniRef50_Q57WS0 Cluster: Protein disulfide isomerase, putative;
           n=3; Trypanosoma|Rep: Protein disulfide isomerase,
           putative - Trypanosoma brucei
          Length = 377

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDV 255
           FVLFY   CGHCK+L P ++ L + ++N+ D+
Sbjct: 177 FVLFYAPWCGHCKRLHPSFESLAKVYQNEKDL 208


>UniRef50_Q6CC54 Cluster: Similar to DEHA0F19404g Debaryomyces
           hansenii; n=1; Yarrowia lipolytica|Rep: Similar to
           DEHA0F19404g Debaryomyces hansenii - Yarrowia lipolytica
           (Candida lipolytica)
          Length = 364

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
 Frame = +1

Query: 157 HEHFVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           H   V FY   CGHCK++ P YD+L   + + DDV + +
Sbjct: 34  HPTLVKFYAPWCGHCKKMGPDYDQLASVYAHTDDVEIAR 72


>UniRef50_A6RP52 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 251

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 2/40 (5%)
 Frame = +3

Query: 300 KITSFPTIKLYSKDNQVHD--YNGERTLAGLTKFVETDGE 413
           +I  FPTIKLY   N+ +   YNG R++  L KF++ +G+
Sbjct: 145 EIQGFPTIKLYKAGNKKNPVTYNGSRSIEDLIKFIKENGQ 184


>UniRef50_Q00248 Cluster: Protein disulfide-isomerase precursor;
           n=39; cellular organisms|Rep: Protein
           disulfide-isomerase precursor - Aspergillus oryzae
          Length = 515

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
 Frame = +3

Query: 303 ITSFPTIKLYS---KDNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEEDVPAR 473
           IT FPTIKL++   KD+ V +Y G RT+  L  FV+ +G+       V   +E+E   A 
Sbjct: 432 ITGFPTIKLFAAGAKDSPV-EYEGSRTVEDLANFVKENGKHKVDALEVDPKKEQESGDAT 490

Query: 474 D 476
           +
Sbjct: 491 E 491


>UniRef50_Q01AS5 Cluster: Thioredoxin/protein disulfide isomerase;
           n=2; Ostreococcus|Rep: Thioredoxin/protein disulfide
           isomerase - Ostreococcus tauri
          Length = 191

 Score = 37.1 bits (82), Expect = 0.37
 Identities = 13/26 (50%), Positives = 20/26 (76%)
 Frame = +1

Query: 178 YRCGHCKQLVPIYDKLGEHFENDDDV 255
           +RCGHCK L P + +LGE F ++++V
Sbjct: 13  HRCGHCKALAPAWKQLGEAFADNENV 38


>UniRef50_Q4E3F7 Cluster: Protein disulfide isomerase, putative;
           n=3; Trypanosoma cruzi|Rep: Protein disulfide isomerase,
           putative - Trypanosoma cruzi
          Length = 481

 Score = 37.1 bits (82), Expect = 0.37
 Identities = 13/22 (59%), Positives = 16/22 (72%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDD 249
           CGHCK L PIY K+ + FE+ D
Sbjct: 380 CGHCKNLAPIYAKVAKEFESSD 401


>UniRef50_Q9C1Z8 Cluster: Protein disulphide isomerase; n=1; Pichia
           pastoris|Rep: Protein disulphide isomerase - Pichia
           pastoris (Yeast)
          Length = 517

 Score = 37.1 bits (82), Expect = 0.37
 Identities = 12/25 (48%), Positives = 18/25 (72%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVS 258
           CGHCK++ P Y++L   + ND+D S
Sbjct: 404 CGHCKRMAPAYEELATLYANDEDAS 428



 Score = 33.5 bits (73), Expect = 4.6
 Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 10/77 (12%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLYSKDNQVHD--YNGERTLAGLTKFV------ETDGEGAEPVPSV 437
           N++++  I  +PT+ LY   ++ +   Y+G R L  L +FV      + D     PV   
Sbjct: 441 NDVDNVDIQGYPTLILYPAGDKSNPQLYDGSRDLESLAEFVKERGTHKVDALALRPVEEE 500

Query: 438 TEFEE--EEDVPARDEL 482
            E EE  E +  A DEL
Sbjct: 501 KEAEEEAESEADAHDEL 517


>UniRef50_Q8IQL9 Cluster: CG6988-PB, isoform B; n=1; Drosophila
           melanogaster|Rep: CG6988-PB, isoform B - Drosophila
           melanogaster (Fruit fly)
          Length = 175

 Score = 36.7 bits (81), Expect = 0.49
 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
 Frame = +1

Query: 253 VSLPKSTPPPTNWNTPRSRPSQRSN-FXXXXXXXXXXXXXGHWPASPSSLRPTVKAP 420
           +SLP+ TP PT+W   RSRPS +SN               G    S SS  PTV+ P
Sbjct: 79  LSLPRWTPLPTSWRALRSRPSPQSNTSARRTTRSSTSTWTGLSMISSSSSMPTVRWP 135


>UniRef50_Q96VF3 Cluster: Putative uncharacterized protein; n=3;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 487

 Score = 36.7 bits (81), Expect = 0.49
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 2/33 (6%)
 Frame = +1

Query: 160 EHFVLFYR--CGHCKQLVPIYDKLGEHFENDDD 252
           +  V FY   CGHCK+L P YD LGE ++   D
Sbjct: 368 DKLVEFYAPWCGHCKKLAPTYDTLGEKYKAHKD 400


>UniRef50_Q8NBS9 Cluster: Thioredoxin domain-containing protein 5
           precursor; n=32; Euteleostomi|Rep: Thioredoxin
           domain-containing protein 5 precursor - Homo sapiens
           (Human)
          Length = 432

 Score = 36.7 bits (81), Expect = 0.49
 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
 Frame = +1

Query: 154 QHEHFVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           Q +HF+ F+   CGHCK L P +++L    E+ + V + K
Sbjct: 205 QGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGK 244



 Score = 36.3 bits (80), Expect = 0.65
 Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 2/35 (5%)
 Frame = +1

Query: 163 HFVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSL 261
           HFV+F+   CGHC++L P ++ LG+ + + +D  +
Sbjct: 80  HFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKV 114


>UniRef50_A2EFV6 Cluster: Thioredoxin family protein; n=1;
           Trichomonas vaginalis G3|Rep: Thioredoxin family protein
           - Trichomonas vaginalis G3
          Length = 369

 Score = 36.3 bits (80), Expect = 0.65
 Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
 Frame = +1

Query: 166 FVLFY--RCGHCKQLVPIYDKLGEHFENDDDV 255
           FV  Y   CGHCK++ P ++KL E ++ND  V
Sbjct: 30  FVFCYSPHCGHCKEIHPDWEKLAEEYKNDPKV 61


>UniRef50_A2EE81 Cluster: Thioredoxin family protein; n=1;
           Trichomonas vaginalis G3|Rep: Thioredoxin family protein
           - Trichomonas vaginalis G3
          Length = 368

 Score = 36.3 bits (80), Expect = 0.65
 Identities = 12/24 (50%), Positives = 18/24 (75%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDV 255
           CGHCK ++P ++KL E +END  +
Sbjct: 38  CGHCKAVLPYWEKLKEKYENDKHI 61


>UniRef50_Q4PDL1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 398

 Score = 36.3 bits (80), Expect = 0.65
 Identities = 13/26 (50%), Positives = 17/26 (65%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSL 261
           CGHCK L PIY+K+ + F +  D  L
Sbjct: 50  CGHCKNLAPIYEKVADAFADQKDAVL 75



 Score = 35.1 bits (77), Expect = 1.5
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDD 252
           CGHCK L P Y ++ + F  DDD
Sbjct: 171 CGHCKNLNPTYQQVAQDFAGDDD 193


>UniRef50_O22263 Cluster: Probable protein disulfide-isomerase A6
           precursor; n=21; Magnoliophyta|Rep: Probable protein
           disulfide-isomerase A6 precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 361

 Score = 36.3 bits (80), Expect = 0.65
 Identities = 14/28 (50%), Positives = 18/28 (64%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK+L P Y+KLG  F+    V + K
Sbjct: 52  CGHCKKLAPEYEKLGASFKKAKSVLIAK 79



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 14/33 (42%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQV-HDYNGERTLAGLTKFV 398
           ++ FPT+K + KDN+  HDY+G R L     F+
Sbjct: 213 VSGFPTLKFFPKDNKAGHDYDGGRDLDDFVSFI 245



 Score = 33.1 bits (72), Expect = 6.0
 Identities = 11/24 (45%), Positives = 16/24 (66%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDV 255
           CGHCK L P Y+K+   F+ ++ V
Sbjct: 171 CGHCKSLAPTYEKVATVFKQEEGV 194


>UniRef50_Q92249 Cluster: Protein disulfide-isomerase erp38
           precursor; n=18; Pezizomycotina|Rep: Protein
           disulfide-isomerase erp38 precursor - Neurospora crassa
          Length = 369

 Score = 36.3 bits (80), Expect = 0.65
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L P ++KL   F +D ++++ K
Sbjct: 170 CGHCKNLAPTWEKLAATFASDPEITIAK 197



 Score = 32.7 bits (71), Expect = 8.0
 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQV-HDYNGERTLAGLTKFV 398
           ++ FPTIK + K +    DYNG R+ A L KF+
Sbjct: 214 VSGFPTIKFFPKGSTTPEDYNGGRSEADLVKFL 246


>UniRef50_A5C1Q6 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 530

 Score = 35.9 bits (79), Expect = 0.86
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHC++L PI ++    F+ND D+ + K
Sbjct: 441 CGHCQRLAPILEEAAVSFQNDPDIIIAK 468


>UniRef50_Q4UG82 Cluster: Protein disulfide isomerase, putative;
           n=2; Theileria|Rep: Protein disulfide isomerase,
           putative - Theileria annulata
          Length = 524

 Score = 35.9 bits (79), Expect = 0.86
 Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLYSKDNQVHD--YNGERTLAGLTKFVETD 407
           NE+E  +I+ FPTI L+   N+     YNG  TL  ++ F+E++
Sbjct: 453 NEVEDMEISQFPTIALFQSGNKTDPLFYNGPDTLEDISMFLESN 496


>UniRef50_Q9SRG3 Cluster: Protein disulfide-isomerase 2 precursor;
           n=50; Magnoliophyta|Rep: Protein disulfide-isomerase 2
           precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 508

 Score = 35.9 bits (79), Expect = 0.86
 Identities = 13/28 (46%), Positives = 19/28 (67%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHC++L PI D++   F+ND  V + K
Sbjct: 402 CGHCQKLAPILDEVALSFQNDPSVIIAK 429


>UniRef50_Q5CXJ5 Cluster: Thioredoxin; protein disulfide isomerase
           A6, signal peptide, possible transmembrane domain in
           C-terminal region; n=3; Cryptosporidium|Rep:
           Thioredoxin; protein disulfide isomerase A6, signal
           peptide, possible transmembrane domain in C-terminal
           region - Cryptosporidium parvum Iowa II
          Length = 524

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV FY   CGHC+ L P   K+ EH++ ++ V + K
Sbjct: 59  FVKFYAPWCGHCRHLYPEILKVSEHYKGNEKVKIAK 94


>UniRef50_UPI0000498890 Cluster: protein disulfide isomerase; n=2;
           Entamoeba histolytica HM-1:IMSS|Rep: protein disulfide
           isomerase - Entamoeba histolytica HM-1:IMSS
          Length = 127

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 11/24 (45%), Positives = 18/24 (75%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDV 255
           CGHCK+L P Y+++ + F  ++DV
Sbjct: 47  CGHCKRLAPTYEEVAQAFTENEDV 70


>UniRef50_Q9FF55 Cluster: Protein disulphide isomerase-like protein;
           n=16; Magnoliophyta|Rep: Protein disulphide
           isomerase-like protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 597

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHC+ L P+Y+KL +H  + D + + K
Sbjct: 471 CGHCQALEPMYNKLAKHLRSIDSLVITK 498


>UniRef50_Q9GRI2 Cluster: Protein disulfide isomerase precursor;
           n=9; Plasmodium|Rep: Protein disulfide isomerase
           precursor - Plasmodium falciparum
          Length = 483

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 12/28 (42%), Positives = 18/28 (64%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK+L P+Y+ LG   +  D + + K
Sbjct: 384 CGHCKKLEPVYEDLGRKLKKYDSIIVAK 411


>UniRef50_Q6BKX9 Cluster: Debaryomyces hansenii chromosome F of
           strain CBS767 of Debaryomyces hansenii; n=1;
           Debaryomyces hansenii|Rep: Debaryomyces hansenii
           chromosome F of strain CBS767 of Debaryomyces hansenii -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 392

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 14/29 (48%), Positives = 21/29 (72%), Gaps = 1/29 (3%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKL-GEHFENDDDVSLPK 267
           CGHCK L+PI++KL  + + NDD + + K
Sbjct: 176 CGHCKTLLPIWEKLANDVYVNDDKIVIGK 204



 Score = 34.3 bits (75), Expect = 2.6
 Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
 Frame = +1

Query: 169 VLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           V FY   C HCK ++P Y+++   FEN+ +V + K
Sbjct: 42  VKFYADWCRHCKNMLPAYEEVSRLFENEPNVQIVK 76


>UniRef50_Q5A5F2 Cluster: Likely protein disulfide isomerase; n=5;
           Saccharomycetales|Rep: Likely protein disulfide
           isomerase - Candida albicans (Yeast)
          Length = 560

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 3/44 (6%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHF-ENDDDVSLPKSTPPPTN 288
           FV +Y   CGHCK+L P +++L E F  N DD  +  +    TN
Sbjct: 414 FVKYYAPWCGHCKKLAPTWEELAEIFGSNKDDAKVVVADIDHTN 457


>UniRef50_P30101 Cluster: Protein disulfide-isomerase A3 precursor;
           n=53; Eumetazoa|Rep: Protein disulfide-isomerase A3
           precursor - Homo sapiens (Human)
          Length = 505

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L P Y +LGE    D ++ + K
Sbjct: 406 CGHCKNLEPKYKELGEKLSKDPNIVIAK 433


>UniRef50_Q8H703 Cluster: Protein disulfide-isomerase; n=1;
           Phytophthora infestans|Rep: Protein disulfide-isomerase
           - Phytophthora infestans (Potato late blight fungus)
          Length = 210

 Score = 34.7 bits (76), Expect = 2.0
 Identities = 12/25 (48%), Positives = 18/25 (72%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVS 258
           CGHCK+LVPIY+K+    +   +V+
Sbjct: 62  CGHCKKLVPIYEKVASELKGQVNVA 86


>UniRef50_Q2GVJ5 Cluster: Putative uncharacterized protein; n=1;
            Chaetomium globosum|Rep: Putative uncharacterized protein
            - Chaetomium globosum (Soil fungus)
          Length = 1351

 Score = 34.7 bits (76), Expect = 2.0
 Identities = 20/58 (34%), Positives = 29/58 (50%)
 Frame = +3

Query: 330  YSKDNQVHDYNGERTLAGLTKFVETDGEGAEPVPSVTEFEEEEDVPARDEL*TLGRGA 503
            YS D +    +G          V +DG      PS ++ +E+ED+PAR  L + GRGA
Sbjct: 1270 YSTDGEGASRSGSEHGGEAGSEVGSDGLSGALEPSDSDEDEDEDIPARPSLASRGRGA 1327


>UniRef50_A1DGY3 Cluster: Disulfide isomerase, putative; n=10;
           Pezizomycotina|Rep: Disulfide isomerase, putative -
           Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
           181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
           3700 / NRRL 181))
          Length = 737

 Score = 34.7 bits (76), Expect = 2.0
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = +3

Query: 312 FPTIKLYSKDNQVHDYNGERTLAGLTKFVETDGEGAEP 425
           FPT  LY     V  + G +T+ GL++FVE   E   P
Sbjct: 156 FPTFSLYHNGKLVEQFEGAKTMEGLSEFVEGKLESIRP 193


>UniRef50_UPI0000ECAAC5 Cluster: protein disulfide isomerase-like
           protein of the testis; n=2; Gallus gallus|Rep: protein
           disulfide isomerase-like protein of the testis - Gallus
           gallus
          Length = 480

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 15/36 (41%), Positives = 25/36 (69%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV+FY      C++L+PI+D+LGE +++  DV + K
Sbjct: 418 FVMFYAPWSYDCRKLLPIWDELGEKYQSHKDVIIAK 453


>UniRef50_Q869Q9 Cluster: Similar to Acanthamoeba castellanii
           (Amoeba). Disulfide-like protein; n=2; Dictyostelium
           discoideum|Rep: Similar to Acanthamoeba castellanii
           (Amoeba). Disulfide-like protein - Dictyostelium
           discoideum (Slime mold)
          Length = 347

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 16/32 (50%), Positives = 22/32 (68%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFV 398
           I S+PTIK+  K N V+D  GE+TL  L +F+
Sbjct: 115 IRSYPTIKVI-KGNSVYDMKGEKTLNSLNEFI 145


>UniRef50_Q5XWD1 Cluster: Protein disulfide isomerase; n=2;
           Entamoeba histolytica|Rep: Protein disulfide isomerase -
           Entamoeba histolytica
          Length = 337

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 14/32 (43%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDV 255
           FV F+   CGHCK+L P Y KL + +++  D+
Sbjct: 36  FVKFFAPWCGHCKKLAPEYIKLADAYKDKQDI 67


>UniRef50_A7AV78 Cluster: Protein disulfide-isomerase, putative;
           n=1; Babesia bovis|Rep: Protein disulfide-isomerase,
           putative - Babesia bovis
          Length = 531

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLY--SKDNQVHDYNGERTLAGLTKFVETD 407
           NE+E+T ++ FPT+ LY     +Q   Y G+  +  L  F+ET+
Sbjct: 460 NEVENTTVSEFPTVVLYPHGAKHQPIQYTGKIVMEDLAHFLETE 503


>UniRef50_A0BSE8 Cluster: Chromosome undetermined scaffold_125,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_125,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 472

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 17/33 (51%), Positives = 23/33 (69%)
 Frame = +3

Query: 300 KITSFPTIKLYSKDNQVHDYNGERTLAGLTKFV 398
           K++SFPTI L  K + V  YNG+R+ +GL  FV
Sbjct: 93  KVSSFPTIILLIKGHAV-PYNGDRSASGLMNFV 124


>UniRef50_Q8LSK4 Cluster: Protein disulfide isomerase-like PDI-H;
           n=3; Physcomitrella patens|Rep: Protein disulfide
           isomerase-like PDI-H - Physcomitrella patens (Moss)
          Length = 524

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 14/28 (50%), Positives = 18/28 (64%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK L P Y+KLGE  ++   V + K
Sbjct: 392 CGHCKSLEPEYNKLGELLKDVKSVVIAK 419


>UniRef50_Q24I64 Cluster: Thioredoxin family protein; n=1;
           Tetrahymena thermophila SB210|Rep: Thioredoxin family
           protein - Tetrahymena thermophila SB210
          Length = 218

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 13/24 (54%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGE 231
           F +FY   CGHCK+L+P YD+  E
Sbjct: 50  FGMFYAPWCGHCKKLIPTYDEFAE 73


>UniRef50_A7SIZ4 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 542

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 12/33 (36%), Positives = 23/33 (69%)
 Frame = +1

Query: 169 VLFYRCGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           +L   C HC +L PI+++L E F+++ D+++ K
Sbjct: 151 LLLLLCIHCIKLAPIWERLAEDFKDNADITISK 183


>UniRef50_A0EAP3 Cluster: Chromosome undetermined scaffold_86, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_86,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 195

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 11/35 (31%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
 Frame = +1

Query: 157 HEHFVLFYR--CGHCKQLVPIYDKLGEHFENDDDV 255
           H  F+LFYR  C HC++++P+++   E+ +    +
Sbjct: 41  HSWFILFYRPSCPHCQKVLPVWESFAEYNQTSSKI 75


>UniRef50_A0CHN0 Cluster: Chromosome undetermined scaffold_182,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_182,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 483

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
 Frame = +3

Query: 282 NELEHTKITSFPTIKLY--SKDNQVHDYNGERTLAGLTKFVE 401
           NE+E   I SFPTIK +   + NQ+ DY+  R  A    F++
Sbjct: 426 NEIEGVNIESFPTIKFWKNGQKNQIIDYSSGRDEANFISFLK 467


>UniRef50_Q5KQ34 Cluster: Disulfide-isomerase, putative; n=1;
           Filobasidiella neoformans|Rep: Disulfide-isomerase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 411

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 11/24 (45%), Positives = 17/24 (70%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDV 255
           CGHCK + P Y+K+ + F ++ DV
Sbjct: 170 CGHCKNMKPAYEKVAKVFSSEPDV 193



 Score = 33.5 bits (73), Expect = 4.6
 Identities = 11/21 (52%), Positives = 14/21 (66%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFEND 246
           CGHCK L P Y++L + F  D
Sbjct: 50  CGHCKNLAPTYERLADAFPTD 70


>UniRef50_P17967 Cluster: Protein disulfide-isomerase precursor;
           n=6; Saccharomycetales|Rep: Protein disulfide-isomerase
           precursor - Saccharomyces cerevisiae (Baker's yeast)
          Length = 522

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
 Frame = +1

Query: 169 VLFYR--CGHCKQLVPIYDKLGEHFEN-DDDVSLPK 267
           VL+Y   CGHCK+L P Y +L + + N   DV + K
Sbjct: 399 VLYYAPWCGHCKRLAPTYQELADTYANATSDVLIAK 434


>UniRef50_Q00002 Cluster: Protein disulfide-isomerase; n=1;
           Alternaria alternata|Rep: Protein disulfide-isomerase -
           Alternaria alternata (Alternaria rot fungus)
          Length = 436

 Score = 33.9 bits (74), Expect = 3.5
 Identities = 11/22 (50%), Positives = 17/22 (77%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDD 249
           CGHCK L P Y++LG+ + +D+
Sbjct: 266 CGHCKALAPKYEELGQLYASDE 287


>UniRef50_A3B992 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 235

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = +1

Query: 235 FENDDDVSLPKSTPPPTNWNTPRSRPSQRS 324
           F++D D  L +STPPP +W +P +  + RS
Sbjct: 137 FQDDIDAGLCQSTPPPPSWPSPPAAANARS 166


>UniRef50_Q582J4 Cluster: Protein disulfide isomerase, putative;
           n=1; Trypanosoma brucei|Rep: Protein disulfide
           isomerase, putative - Trypanosoma brucei
          Length = 135

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 13/36 (36%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           FV+FY   CGHCK+L P +++L +  +++  V + +
Sbjct: 49  FVMFYAPWCGHCKRLKPKWEELAKEMKDETSVVIAR 84


>UniRef50_Q5AKR3 Cluster: Potential thioredoxin; n=3;
           Saccharomycetales|Rep: Potential thioredoxin - Candida
           albicans (Yeast)
          Length = 299

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 14/33 (42%), Positives = 21/33 (63%), Gaps = 2/33 (6%)
 Frame = +1

Query: 169 VLFYR--CGHCKQLVPIYDKLGEHFENDDDVSL 261
           V FY   CG+C++L P+Y KLG++   D   S+
Sbjct: 52  VKFYAPWCGYCQKLQPVYHKLGKYINKDAKYSI 84


>UniRef50_P13667 Cluster: Protein disulfide-isomerase A4 precursor;
           n=44; Deuterostomia|Rep: Protein disulfide-isomerase A4
           precursor - Homo sapiens (Human)
          Length = 645

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 11/28 (39%), Positives = 18/28 (64%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCKQL P+Y+ L + ++    + + K
Sbjct: 555 CGHCKQLEPVYNSLAKKYKGQKGLVIAK 582


>UniRef50_Q13087 Cluster: Protein disulfide-isomerase A2 precursor;
           n=21; Theria|Rep: Protein disulfide-isomerase A2
           precursor - Homo sapiens (Human)
          Length = 525

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 12/32 (37%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDV 255
           FV FY   C HCK++ P ++ L E +++ +D+
Sbjct: 410 FVKFYAPWCTHCKEMAPAWEALAEKYQDHEDI 441


>UniRef50_P12865 Cluster: Bloodstream-specific protein 2 precursor;
           n=3; Trypanosoma brucei|Rep: Bloodstream-specific
           protein 2 precursor - Trypanosoma brucei brucei
          Length = 497

 Score = 33.5 bits (73), Expect = 4.6
 Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
 Frame = +1

Query: 169 VLFYR--CGHCKQLVPIYDKLGEHFENDD 249
           +LF+   CGHCK   P +DK+ + F+  D
Sbjct: 371 ILFFAPWCGHCKNFAPTFDKIAKEFDATD 399


>UniRef50_Q55FU1 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 276

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 14/39 (35%), Positives = 22/39 (56%)
 Frame = +3

Query: 291 EHTKITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETD 407
           E  KI S+P I  +     V  YNG+R++  L +F+E +
Sbjct: 214 EKFKIESYPNIYFFKDGKNVDKYNGDRSVNSLIEFLENN 252


>UniRef50_Q54BW3 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 417

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPK 267
           CGHCK+L P+Y++L + +  D + S  K
Sbjct: 51  CGHCKRLAPVYEELAQLYNVDIENSKVK 78


>UniRef50_A3LVR0 Cluster: Predicted protein; n=3;
           Saccharomycetaceae|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 310

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 2/33 (6%)
 Frame = +1

Query: 169 VLFYR--CGHCKQLVPIYDKLGEHFENDDDVSL 261
           V FY   CG+C+QL P Y KLG++   D   ++
Sbjct: 52  VKFYAPWCGYCQQLKPAYKKLGKYLHQDSQYAV 84


>UniRef50_UPI00015B4150 Cluster: PREDICTED: similar to protein
           disulfide isomerase, putative; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to protein disulfide
           isomerase, putative - Nasonia vitripennis
          Length = 429

 Score = 32.7 bits (71), Expect = 8.0
 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
 Frame = +3

Query: 300 KITSFPTIKLYSKDNQVHDYNGERTLAGLTKF-VETDGEGAEPVPSVTEF 446
           KI  FPTI L+ K +Q   YNG+RT   + KF     G   + V   T F
Sbjct: 90  KIKGFPTI-LFLKGDQQFVYNGDRTRDEIVKFATRLSGPPVQEVTRTTSF 138


>UniRef50_UPI0000D57458 Cluster: PREDICTED: similar to CG8983-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG8983-PA, isoform A - Tribolium castaneum
          Length = 491

 Score = 32.7 bits (71), Expect = 8.0
 Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKFV--ETDGEGAEPVPSVTEFEE 452
           ++SFPT+K++     +  Y G R    + K++  + DG+  E + SV E E+
Sbjct: 94  VSSFPTLKIFRNGKFLKAYEGPREAPAIAKYMKAQVDGDSRE-LGSVAELED 144


>UniRef50_A0DI01 Cluster: Chromosome undetermined scaffold_51, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_51,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 603

 Score = 32.7 bits (71), Expect = 8.0
 Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 2/32 (6%)
 Frame = +1

Query: 166 FVLFYR--CGHCKQLVPIYDKLGEHFENDDDV 255
           FV  Y   CGHCK+L P Y++L +     D V
Sbjct: 371 FVKIYAPWCGHCKKLAPAYEELAQQLNRKDIV 402


>UniRef50_A0D787 Cluster: Chromosome undetermined scaffold_4, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_4,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 484

 Score = 32.7 bits (71), Expect = 8.0
 Identities = 10/32 (31%), Positives = 19/32 (59%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDDVSLPKSTPP 279
           CGHCKQ  P+YD++     ++ ++ + +   P
Sbjct: 400 CGHCKQFKPLYDQIAYELRDNPNIVVAQINAP 431


>UniRef50_Q6FPP9 Cluster: Similar to sp|P40557 Saccharomyces
           cerevisiae YIL005w; n=1; Candida glabrata|Rep: Similar
           to sp|P40557 Saccharomyces cerevisiae YIL005w - Candida
           glabrata (Yeast) (Torulopsis glabrata)
          Length = 708

 Score = 32.7 bits (71), Expect = 8.0
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = +3

Query: 303 ITSFPTIKLYSKDNQVHDYNGERTLAGLTKF 395
           I ++PTI+LY  D  + +Y+G+RT     KF
Sbjct: 107 IRAYPTIRLYGPDGFLEEYHGKRTKEEFLKF 137


>UniRef50_O51088 Cluster: Thioredoxin; n=6; Borrelia burgdorferi
           group|Rep: Thioredoxin - Borrelia burgdorferi (Lyme
           disease spirochete)
          Length = 117

 Score = 32.7 bits (71), Expect = 8.0
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = +1

Query: 184 CGHCKQLVPIYDKLGEHFENDDD 252
           CG CK L PI++KL + +EN  D
Sbjct: 40  CGPCKMLSPIFEKLSKKYENSID 62


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 552,490,890
Number of Sequences: 1657284
Number of extensions: 9985182
Number of successful extensions: 33922
Number of sequences better than 10.0: 91
Number of HSP's better than 10.0 without gapping: 31996
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33876
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49586781480
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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