BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdV40096 (823 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9GZJ8 Cluster: Mre11; n=1; Bombyx mori|Rep: Mre11 - Bo... 230 3e-59 UniRef50_UPI0000D566D3 Cluster: PREDICTED: similar to CG16928-PA... 140 3e-32 UniRef50_Q54BN2 Cluster: DNA repair exonuclease; n=1; Dictyostel... 138 2e-31 UniRef50_UPI0000DB6F19 Cluster: PREDICTED: similar to meiotic re... 132 8e-30 UniRef50_Q9XYZ4 Cluster: CG16928-PA; n=5; Diptera|Rep: CG16928-P... 132 8e-30 UniRef50_UPI00015B5FB8 Cluster: PREDICTED: similar to meiotic re... 132 1e-29 UniRef50_P49959 Cluster: Double-strand break repair protein MRE1... 128 2e-28 UniRef50_A7SIW1 Cluster: Predicted protein; n=1; Nematostella ve... 124 4e-27 UniRef50_A5E785 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25 UniRef50_Q09683 Cluster: DNA repair protein rad32; n=1; Schizosa... 118 2e-25 UniRef50_Q9C291 Cluster: Double-strand break repair protein mus-... 117 3e-25 UniRef50_A1CU25 Cluster: Meiotic recombination protein Mre11; n=... 116 9e-25 UniRef50_Q586P4 Cluster: Endo/exonuclease Mre11; n=3; Trypanosom... 113 7e-24 UniRef50_Q9XGM2 Cluster: Double-strand break repair protein MRE1... 113 7e-24 UniRef50_Q6BL74 Cluster: Debaryomyces hansenii chromosome F of s... 111 3e-23 UniRef50_Q9UVN9 Cluster: Double-strand break repair protein MRE1... 103 5e-21 UniRef50_A4HFW3 Cluster: Endo/exonuclease Mre11, putative; n=5; ... 103 7e-21 UniRef50_Q4P5A9 Cluster: Putative uncharacterized protein; n=1; ... 99 7e-20 UniRef50_Q5KHA6 Cluster: Meiotic DNA double-strand break process... 99 2e-19 UniRef50_Q6ZBS2 Cluster: Putative DNA repair and meiosis protein... 97 6e-19 UniRef50_UPI00015B5FB6 Cluster: PREDICTED: similar to endo/exonu... 96 8e-19 UniRef50_Q016A4 Cluster: Mre11 protein; n=3; Ostreococcus|Rep: M... 96 8e-19 UniRef50_Q6CEM3 Cluster: Yarrowia lipolytica chromosome B of str... 96 8e-19 UniRef50_A5DLP0 Cluster: Putative uncharacterized protein; n=1; ... 93 6e-18 UniRef50_P32829 Cluster: Double-strand break repair protein MRE1... 93 6e-18 UniRef50_Q8SRV0 Cluster: DOUBLE-STRAND BREAK DNA REPAIR PROTEIN;... 91 3e-17 UniRef50_Q23255 Cluster: Double-strand break repair protein mre-... 91 4e-17 UniRef50_A3FQD2 Cluster: DNA repair and meiosis protein Mre11; n... 87 4e-16 UniRef50_Q0MR25 Cluster: MRE11-like protein; n=1; Penicillium ma... 87 4e-16 UniRef50_A5YZR9 Cluster: MRE11B; n=2; Magnoliophyta|Rep: MRE11B ... 84 5e-15 UniRef50_Q22G12 Cluster: Ser/Thr protein phosphatase family prot... 76 9e-13 UniRef50_Q86C23 Cluster: Mre11; n=2; Entamoeba histolytica|Rep: ... 69 1e-10 UniRef50_UPI000049A054 Cluster: DNA repair protein rad32; n=1; E... 69 2e-10 UniRef50_Q4U965 Cluster: Double-strand break repair protein, put... 66 1e-09 UniRef50_Q7RBG7 Cluster: Rad32-related; n=6; Plasmodium (Vinckei... 64 5e-09 UniRef50_A5K9T7 Cluster: DNA repair exonuclease, putative; n=1; ... 63 7e-09 UniRef50_A2ECB0 Cluster: Ser/Thr protein phosphatase, putative; ... 63 9e-09 UniRef50_A0DUM4 Cluster: Chromosome undetermined scaffold_64, wh... 62 2e-08 UniRef50_Q8I263 Cluster: DNA repair exonuclease, putative; n=1; ... 60 9e-08 UniRef50_A7AP02 Cluster: DNA repair protein (Mre11) family prote... 60 9e-08 UniRef50_Q8PUY5 Cluster: DNA double-strand break repair protein ... 50 9e-05 UniRef50_Q46FJ9 Cluster: DNA repair protein; n=1; Methanosarcina... 48 2e-04 UniRef50_Q2JK75 Cluster: Ser/Thr protein phosphatase family prot... 45 0.002 UniRef50_A4ENU6 Cluster: Putative ATP-dependent dsDNA exonucleas... 45 0.002 UniRef50_A3HX94 Cluster: DNA repair exonuclease; n=1; Algoriphag... 45 0.002 UniRef50_Q8DMQ1 Cluster: Tll0060 protein; n=1; Synechococcus elo... 44 0.005 UniRef50_A5YS39 Cluster: DNA double-strand break repair protein ... 44 0.006 UniRef50_Q8U1N9 Cluster: DNA double-strand break repair protein ... 44 0.006 UniRef50_Q12VW7 Cluster: Metallophosphoesterase; n=1; Methanococ... 43 0.008 UniRef50_Q3ISN6 Cluster: Conserved DNA repair operon protein; n=... 43 0.011 UniRef50_A2BM15 Cluster: Predicted DNA repair exonuclease; n=1; ... 42 0.014 UniRef50_O29231 Cluster: DNA double-strand break repair protein ... 41 0.033 UniRef50_A0RW71 Cluster: DNA repair exonuclease; n=1; Cenarchaeu... 40 0.075 UniRef50_Q9X1X0 Cluster: Exonuclease, putative; n=3; Thermotoga|... 39 0.17 UniRef50_O67727 Cluster: ATP-dependent dsDNA exonuclease; n=1; A... 39 0.17 UniRef50_Q9UZC9 Cluster: DNA double-strand break repair protein ... 39 0.17 UniRef50_Q3A5P7 Cluster: DNA repair exonuclease; n=1; Pelobacter... 38 0.23 UniRef50_UPI00015BCD31 Cluster: UPI00015BCD31 related cluster; n... 38 0.30 UniRef50_A7DNM9 Cluster: Metallophosphoesterase; n=1; Candidatus... 38 0.30 UniRef50_Q2AI56 Cluster: Exonuclease SbcD; n=1; Halothermothrix ... 38 0.40 UniRef50_UPI00015BAD8F Cluster: metallophosphoesterase; n=1; Ign... 37 0.53 UniRef50_O26641 Cluster: DNA double-strand break repair protein ... 37 0.53 UniRef50_Q74D96 Cluster: Nuclease SbcCD, D subunit, putative; n=... 37 0.70 UniRef50_Q9YFY8 Cluster: DNA double-strand break repair protein ... 37 0.70 UniRef50_Q9AN75 Cluster: ID473; n=1; Bradyrhizobium japonicum|Re... 36 0.93 UniRef50_Q0HTQ0 Cluster: Nuclease SbcCD, D subunit precursor; n=... 36 0.93 UniRef50_Q03B99 Cluster: DNA repair exonuclease; n=4; Lactobacil... 36 0.93 UniRef50_Q7QVF9 Cluster: GLP_90_7352_9805; n=3; Giardia intestin... 36 0.93 UniRef50_Q2NFC6 Cluster: DNA double-strand break repair protein ... 36 0.93 UniRef50_Q1FMZ5 Cluster: Nuclease SbcCD, D subunit; n=1; Clostri... 36 1.2 UniRef50_Q9HRW4 Cluster: DNA double-strand break repair protein ... 36 1.2 UniRef50_A6TVN1 Cluster: Nuclease SbcCD, D subunit; n=3; Clostri... 36 1.6 UniRef50_Q8TXI3 Cluster: DNA double-strand break repair protein ... 36 1.6 UniRef50_Q5LYZ3 Cluster: ATP-dependent dsDNA exonuclease; n=6; S... 35 2.1 UniRef50_Q2AE44 Cluster: Metallophosphoesterase; n=1; Halothermo... 35 2.1 UniRef50_A5IU09 Cluster: Metallophosphoesterase; n=16; Staphyloc... 35 2.1 UniRef50_A1S0I8 Cluster: Metallophosphoesterase; n=1; Thermofilu... 35 2.1 UniRef50_P62132 Cluster: DNA double-strand break repair protein ... 35 2.1 UniRef50_A4YET4 Cluster: Metallophosphoesterase; n=1; Metallosph... 35 2.8 UniRef50_Q67MD2 Cluster: DNA repair exonuclease; n=1; Symbiobact... 34 3.7 UniRef50_Q5SIS5 Cluster: Exonuclease SbcD; n=2; Thermus thermoph... 34 3.7 UniRef50_Q22P75 Cluster: Putative uncharacterized protein; n=1; ... 34 3.7 UniRef50_Q6L2H7 Cluster: DNA repair protein; n=2; Thermoplasmata... 34 3.7 UniRef50_Q38Y02 Cluster: Putative metallo-phosphoesterase; n=1; ... 34 4.9 UniRef50_Q2S5E8 Cluster: Outer membrane protein, putative; n=1; ... 34 4.9 UniRef50_Q2S4Q6 Cluster: Nuclease SbcCD, D subunit subfamily, pu... 34 4.9 UniRef50_A7HL21 Cluster: Metallophosphoesterase; n=1; Fervidobac... 34 4.9 UniRef50_A7HCA1 Cluster: Nuclease SbcCD, D subunit; n=1; Anaerom... 34 4.9 UniRef50_A7BEB8 Cluster: Putative uncharacterized protein; n=1; ... 34 4.9 UniRef50_Q4XVJ3 Cluster: Putative uncharacterized protein; n=3; ... 34 4.9 UniRef50_Q88WS0 Cluster: Exonuclease SbcD; n=2; Lactobacillales|... 33 6.5 UniRef50_Q74CF0 Cluster: Nuclease SbcCD, D subunit, putative; n=... 33 6.5 UniRef50_Q6I2G3 Cluster: DNA repair exonuclease family protein; ... 33 6.5 UniRef50_Q04FF3 Cluster: DNA repair exonuclease; n=2; Oenococcus... 33 6.5 UniRef50_Q6CKL0 Cluster: Similarity; n=1; Kluyveromyces lactis|R... 33 6.5 UniRef50_Q7UKG1 Cluster: Probable phosphoesterase yhaO-putative ... 33 8.6 UniRef50_Q65LT8 Cluster: YhaO; n=4; Bacillus|Rep: YhaO - Bacillu... 33 8.6 UniRef50_Q2RL80 Cluster: Metallophosphoesterase; n=1; Moorella t... 33 8.6 UniRef50_A6P235 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6 >UniRef50_Q9GZJ8 Cluster: Mre11; n=1; Bombyx mori|Rep: Mre11 - Bombyx mori (Silk moth) Length = 610 Score = 230 bits (563), Expect = 3e-59 Identities = 114/147 (77%), Positives = 120/147 (81%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNH 436 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNH Sbjct: 68 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNH 127 Query: 437 DDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKDQRL 616 DDPVGQGSVSSLDILSITGLVNYF +K L GLSHLKDQRL Sbjct: 128 DDPVGQGSVSSLDILSITGLVNYFGKWTDYTHVRISPVLLQKGLTRLALYGLSHLKDQRL 187 Query: 617 SRLFAEKKVEMERPDETLGLGSIYLYY 697 SRLFAEKKVEMERPDETL ++++ + Sbjct: 188 SRLFAEKKVEMERPDETLDWFNLFVLH 214 Score = 140 bits (338), Expect = 5e-32 Identities = 66/66 (100%), Positives = 66/66 (100%) Frame = +3 Query: 57 MIENDISAWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLG 236 MIENDISAWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLG Sbjct: 1 MIENDISAWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLG 60 Query: 237 GDLFDQ 254 GDLFDQ Sbjct: 61 GDLFDQ 66 Score = 113 bits (272), Expect = 5e-24 Identities = 64/106 (60%), Positives = 66/106 (62%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFH 684 F KWTDYTHVRISPVLLQKGLTRLALYG K F KK E F+ Sbjct: 151 FGKWTDYTHVRISPVLLQKGLTRLALYGLSHLKDQRLSRLFAEKKV-EMERPDETLDWFN 209 Query: 685 LFVLHPNHADRGHSNYIPEGVLPTFRL*CGGLSMIALFVPWKGN*T 822 LFVLH NHADRGHSNYIPEGVLPTFR G + P KGN T Sbjct: 210 LFVLHQNHADRGHSNYIPEGVLPTFRSVVWGHEHDSHICPMKGNKT 255 >UniRef50_UPI0000D566D3 Cluster: PREDICTED: similar to CG16928-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG16928-PA - Tribolium castaneum Length = 555 Score = 140 bits (340), Expect = 3e-32 Identities = 68/138 (49%), Positives = 90/138 (65%), Gaps = 2/138 (1%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNF--SRTVNYEDPNLNISYPILSIHG 430 +P+ +C+ K E+IRKYC GDKPV IE SD +F + +VNYEDPN+N+S PI SIHG Sbjct: 62 RPTPHCIKKTIELIRKYCFGDKPVEIEFFSDPSLHFPGNASVNYEDPNINVSIPIFSIHG 121 Query: 431 NHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKDQ 610 NHDDP G+ VS+LD+ S GLVNYF E + KK GLSH++D+ Sbjct: 122 NHDDPTGKNHVSALDLFSSMGLVNYFGRWDDVTKVEINPILLKKGDSKLALYGLSHIRDE 181 Query: 611 RLSRLFAEKKVEMERPDE 664 RL+RLF +KKV + P++ Sbjct: 182 RLARLFLDKKVVTKTPED 199 Score = 62.5 bits (145), Expect = 1e-08 Identities = 29/57 (50%), Positives = 41/57 (71%) Frame = +3 Query: 84 SPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 S +T RIL+A+D+HLG+ N+ +R D+F FEE+L +A + VD ILLGGDLF + Sbjct: 4 SEANTFRILLATDLHLGYGLNNSIRENDTFRTFEEILQIANKEKVDFILLGGDLFHE 60 Score = 62.1 bits (144), Expect = 2e-08 Identities = 32/85 (37%), Positives = 49/85 (57%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFH 684 F +W D T V I+P+LL+KG ++LALYG + F KK +T ++ F+ Sbjct: 147 FGRWDDVTKVEINPILLKKGDSKLALYGLSHIRDERLARLFLDKKVVT-KTPEDLNDWFN 205 Query: 685 LFVLHPNHADRGHSNYIPEGVLPTF 759 +F+LH N A+RG N+I + +P F Sbjct: 206 VFILHQNRANRGAKNFIADSFIPEF 230 >UniRef50_Q54BN2 Cluster: DNA repair exonuclease; n=1; Dictyostelium discoideum AX4|Rep: DNA repair exonuclease - Dictyostelium discoideum AX4 Length = 689 Score = 138 bits (334), Expect = 2e-31 Identities = 67/140 (47%), Positives = 90/140 (64%), Gaps = 3/140 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSR---TVNYEDPNLNISYPILSIH 427 KPS +C+++ E+ RKYCLGD PV I+ LSDQ NFS TVNYEDPN NIS PI SIH Sbjct: 96 KPSRSCLYRTMELFRKYCLGDSPVRIQFLSDQSVNFSNQFHTVNYEDPNFNISLPIFSIH 155 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 GNHDDP G+G +++LD+LS++ LVNYF + K GL +++D Sbjct: 156 GNHDDPTGEGGLAALDLLSVSNLVNYFGKTEDIDDITVYPLLLGKGETKIAIYGLGNIRD 215 Query: 608 QRLSRLFAEKKVEMERPDET 667 +RL R F ++ V++ RP E+ Sbjct: 216 ERLHRTFQKQSVKLMRPVES 235 Score = 72.1 bits (169), Expect = 2e-11 Identities = 34/61 (55%), Positives = 45/61 (73%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNLLSIVC 278 +RIL+A+D HLG++E DP+RG+DSF +FEE+L A VD++LLGGDLF N S C Sbjct: 43 MRILVATDNHLGYLERDPIRGDDSFNSFEEILKYAHTLKVDMVLLGGDLFHD-NKPSRSC 101 Query: 279 L 281 L Sbjct: 102 L 102 Score = 36.3 bits (80), Expect = 0.93 Identities = 22/85 (25%), Positives = 38/85 (44%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFH 684 F K D + + P+LL KG T++A+YG + +F + + F+ Sbjct: 182 FGKTEDIDDITVYPLLLGKGETKIAIYGLGNIRDERLHRTFQKQSVKLMRPVESKDEWFN 241 Query: 685 LFVLHPNHADRGHSNYIPEGVLPTF 759 + VLH N NY+ E ++ +F Sbjct: 242 ILVLHQNRVAHNPKNYVHEKMIESF 266 >UniRef50_UPI0000DB6F19 Cluster: PREDICTED: similar to meiotic recombination 11 CG16928-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to meiotic recombination 11 CG16928-PA - Apis mellifera Length = 501 Score = 132 bits (320), Expect = 8e-30 Identities = 69/152 (45%), Positives = 92/152 (60%), Gaps = 4/152 (2%) Frame = +2 Query: 254 TKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFS----RTVNYEDPNLNISYPILS 421 TKPS + +C E++RKYCLG K + I+ LSD F +TVNYEDPNLNIS PI S Sbjct: 73 TKPSQTAILRCMELLRKYCLGTKEIKIQFLSDPEVIFRHCAYKTVNYEDPNLNISMPIFS 132 Query: 422 IHGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHL 601 IHGNHDDP G++ S+D+LS++GL+NYF KK GLS++ Sbjct: 133 IHGNHDDP-SFGAIGSMDLLSVSGLINYFGKWTDLTKINIPPLIIKKGETHIALYGLSYI 191 Query: 602 KDQRLSRLFAEKKVEMERPDETLGLGSIYLYY 697 DQRLSRL + K++M RP E +I++ + Sbjct: 192 NDQRLSRLLRDFKIDMLRPTEITDCFNIFVLH 223 Score = 69.3 bits (162), Expect = 1e-10 Identities = 36/69 (52%), Positives = 45/69 (65%), Gaps = 2/69 (2%) Frame = +3 Query: 48 SKIMIENDISAWSPDDTLRILIASDIHLGFMENDP--VRGEDSFIAFEEVLSLAVQCDVD 221 S I N +PDD+++ILIA+DIHLGF N + EDSFI FEE+L + +VD Sbjct: 2 SSTPINNKNEKRNPDDSIKILIATDIHLGFEYNKKRGQQSEDSFITFEEILQYGKEYEVD 61 Query: 222 LILLGGDLF 248 ILLGGDLF Sbjct: 62 FILLGGDLF 70 >UniRef50_Q9XYZ4 Cluster: CG16928-PA; n=5; Diptera|Rep: CG16928-PA - Drosophila melanogaster (Fruit fly) Length = 620 Score = 132 bits (320), Expect = 8e-30 Identities = 67/138 (48%), Positives = 89/138 (64%), Gaps = 4/138 (2%) Frame = +2 Query: 260 PSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNF----SRTVNYEDPNLNISYPILSIH 427 PS N + KC E++R+Y GD+PVS+E+LSDQ + F +++VNYEDPNLNI+ P+ SIH Sbjct: 69 PSQNALHKCIELLRRYTFGDRPVSLEILSDQGQCFHNAVNQSVNYEDPNLNIAIPVFSIH 128 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 GNHDDP G G +SSLD+LS +GLVNYF E +K GLSH+ D Sbjct: 129 GNHDDPSGFGRLSSLDLLSTSGLVNYFGRWTDLTQVEISPVLMRKGESQLALYGLSHIHD 188 Query: 608 QRLSRLFAEKKVEMERPD 661 RL+RL + KV+ P+ Sbjct: 189 GRLARLIKDFKVKFNCPE 206 Score = 80.2 bits (189), Expect = 6e-14 Identities = 37/53 (69%), Positives = 44/53 (83%) Frame = +3 Query: 90 DDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 D+ +RIL+A+D HLG+ E D VRGEDSF AFEE+L LAV DVD+ILLGGDLF Sbjct: 12 DNVIRILVATDNHLGYGEKDAVRGEDSFTAFEEILELAVSEDVDMILLGGDLF 64 Score = 65.3 bits (152), Expect = 2e-09 Identities = 40/96 (41%), Positives = 52/96 (54%), Gaps = 11/96 (11%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PF---KRSETFTSF-----C*KKSGNGETR 660 F +WTD T V ISPVL++KG ++LALYG + + F C + NGE Sbjct: 155 FGRWTDLTQVEISPVLMRKGESQLALYGLSHIHDGRLARLIKDFKVKFNCPENVANGEDG 214 Query: 661 *NIGTG---FHLFVLHPNHADRGHSNYIPEGVLPTF 759 FHL V+H N ADRG NY+PE +LP+F Sbjct: 215 NESKEEEDWFHLLVVHQNRADRGPKNYLPEDLLPSF 250 >UniRef50_UPI00015B5FB8 Cluster: PREDICTED: similar to meiotic recombination repair protein 11 (mre11); n=1; Nasonia vitripennis|Rep: PREDICTED: similar to meiotic recombination repair protein 11 (mre11) - Nasonia vitripennis Length = 664 Score = 132 bits (319), Expect = 1e-29 Identities = 65/140 (46%), Positives = 83/140 (59%), Gaps = 4/140 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFS----RTVNYEDPNLNISYPILSI 424 KP N + KC E++R YCL DKPV I+ L+D FS + VN+EDPNLN+ P+ SI Sbjct: 89 KPPHNVVMKCLELLRTYCLNDKPVKIQFLTDPEAVFSHCAQKVVNFEDPNLNVGIPVFSI 148 Query: 425 HGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLK 604 HGNHDDP G G+V S+D+LS TGL+NYF +K + GLS++ Sbjct: 149 HGNHDDPTGYGAVGSMDVLSATGLINYFGKWTDVTQVSIAPLLIRKGVTTIALYGLSYMN 208 Query: 605 DQRLSRLFAEKKVEMERPDE 664 DQRLSRL K M R D+ Sbjct: 209 DQRLSRLMRNNKFHMLRTDK 228 Score = 60.5 bits (140), Expect = 5e-08 Identities = 30/85 (35%), Positives = 46/85 (54%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFH 684 F KWTD T V I+P+L++KG+T +ALYG + + + + F+ Sbjct: 176 FGKWTDVTQVSIAPLLIRKGVTTIALYGL-SYMNDQRLSRLMRNNKFHMLRTDKADDPFN 234 Query: 685 LFVLHPNHADRGHSNYIPEGVLPTF 759 +FVLH N A ++Y+PE +LP F Sbjct: 235 IFVLHQNRAMHSQNSYVPENLLPDF 259 Score = 58.4 bits (135), Expect = 2e-07 Identities = 27/55 (49%), Positives = 40/55 (72%) Frame = +3 Query: 90 DDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 ++ +++LIA+DIHLG+ E R +DSF FEE+L A +VD++LLGGDLF + Sbjct: 34 ENIMKVLIATDIHLGY-EQTTKREDDSFRTFEEILQYARDHEVDMVLLGGDLFHE 87 >UniRef50_P49959 Cluster: Double-strand break repair protein MRE11A; n=42; Deuterostomia|Rep: Double-strand break repair protein MRE11A - Homo sapiens (Human) Length = 708 Score = 128 bits (308), Expect = 2e-28 Identities = 64/140 (45%), Positives = 83/140 (59%), Gaps = 4/140 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISYPILSI 424 KPS + C E++RKYC+GD+PV E+LSDQ NF + VNY+D NLNIS P+ SI Sbjct: 66 KPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSI 125 Query: 425 HGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLK 604 HGNHDDP G ++ +LDILS G VN+F + + +K GL + Sbjct: 126 HGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIP 185 Query: 605 DQRLSRLFAEKKVEMERPDE 664 D+RL R+F KKV M RP E Sbjct: 186 DERLYRMFVNKKVTMLRPKE 205 Score = 75.8 bits (178), Expect = 1e-12 Identities = 33/59 (55%), Positives = 45/59 (76%) Frame = +3 Query: 78 AWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 A ++T +IL+A+DIHLGFME D VRG D+F+ +E+L LA + +VD ILLGGDLF + Sbjct: 6 ALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHE 64 Score = 56.4 bits (130), Expect = 8e-07 Identities = 30/76 (39%), Positives = 42/76 (55%) Frame = +1 Query: 532 VRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFHLFVLHPNHA 711 + ISPVLLQKG T++ALYG + F KK + + + F+LFV+H N + Sbjct: 162 IDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRS 221 Query: 712 DRGHSNYIPEGVLPTF 759 G +N+IPE L F Sbjct: 222 KHGSTNFIPEQFLDDF 237 >UniRef50_A7SIW1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 720 Score = 124 bits (298), Expect = 4e-27 Identities = 61/140 (43%), Positives = 82/140 (58%), Gaps = 4/140 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISYPILSI 424 KPS + + RK+C+GD+ +E LSDQ NF+ VNYEDPNLN+S P+ SI Sbjct: 104 KPSRRTLHASMALFRKFCMGDRVCEVEFLSDQSINFANNRFPWVNYEDPNLNVSIPVFSI 163 Query: 425 HGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLK 604 HGNHDDP G+G++ +LD+LS+ GLVNYF + +K GL ++ Sbjct: 164 HGNHDDPAGEGNLCALDLLSVCGLVNYFGRPASVDDITVSPLLLQKGATKLALYGLGSVR 223 Query: 605 DQRLSRLFAEKKVEMERPDE 664 D+RL R F KV+M RP E Sbjct: 224 DERLHRTFVNNKVKMLRPKE 243 Score = 72.5 bits (170), Expect = 1e-11 Identities = 32/54 (59%), Positives = 42/54 (77%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 +TL ILIA+D+HLG+ E D VRG DSF+ FEE L +A + +VD ILLGGDL+ + Sbjct: 49 NTLSILIATDVHLGYAEKDQVRGNDSFVTFEETLQIAKKRNVDFILLGGDLYHE 102 Score = 61.7 bits (143), Expect = 2e-08 Identities = 32/76 (42%), Positives = 43/76 (56%) Frame = +1 Query: 532 VRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFHLFVLHPNHA 711 + +SP+LLQKG T+LALYG + +F K + + + F+ FVLH N A Sbjct: 200 ITVSPLLLQKGATKLALYGLGSVRDERLHRTFVNNKVKMLRPKEDPDSWFNAFVLHQNRA 259 Query: 712 DRGHSNYIPEGVLPTF 759 GH+NYIPE L TF Sbjct: 260 KHGHTNYIPEKFLDTF 275 >UniRef50_A5E785 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 669 Score = 118 bits (284), Expect = 2e-25 Identities = 60/142 (42%), Positives = 91/142 (64%), Gaps = 8/142 (5%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSR---TVNYEDPNLNISYPILSIH 427 KP+ M+ + +R C+GD+P +ELLS+ + S VNYEDPNLNIS P+ +I+ Sbjct: 67 KPTKKSMYHVMKSLRANCMGDRPCELELLSEPGETMSNGFDEVNYEDPNLNISVPVFAIN 126 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVL--RGSPSM---GL 592 GNHDD G+G +S+LD+L+++GL+NYF TR + Y K +L +GS G+ Sbjct: 127 GNHDDATGEGMLSALDVLAVSGLINYF---GKTRDNNHDTYLVKPILLQKGSTKFALYGM 183 Query: 593 SHLKDQRLSRLFAEKKVEMERP 658 S+++D++L RLF + +V ERP Sbjct: 184 SNVRDEKLHRLFRDGEVRFERP 205 Score = 70.5 bits (165), Expect = 5e-11 Identities = 29/52 (55%), Positives = 42/52 (80%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 DTL+IL+ +D H+G++ENDP+RG+DS+ F+E+ LA DVD+I+ GGDLF Sbjct: 12 DTLKILLTTDNHVGYLENDPIRGDDSWKTFDEITRLARDHDVDMIIQGGDLF 63 Score = 38.3 bits (85), Expect = 0.23 Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 2/87 (2%) Frame = +1 Query: 505 FCKWTDYTH--VRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTG 678 F K D H + P+LLQKG T+ ALYG + + F + + Sbjct: 153 FGKTRDNNHDTYLVKPILLQKGSTKFALYGMSNVRDEKLHRLFRDGEVRFERPGLHTDEW 212 Query: 679 FHLFVLHPNHADRGHSNYIPEGVLPTF 759 F+ H NHA + IPE LP F Sbjct: 213 FNFLAFHQNHAVHTFKSSIPENYLPHF 239 >UniRef50_Q09683 Cluster: DNA repair protein rad32; n=1; Schizosaccharomyces pombe|Rep: DNA repair protein rad32 - Schizosaccharomyces pombe (Fission yeast) Length = 649 Score = 118 bits (284), Expect = 2e-25 Identities = 60/139 (43%), Positives = 79/139 (56%), Gaps = 4/139 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT----VNYEDPNLNISYPILSI 424 KPS +++ +R CLGDKP +ELLSD T +NY DPN+N++ P+ SI Sbjct: 71 KPSRKALYQALRSLRLNCLGDKPCELELLSDTSLTTGDTAVCNINYLDPNINVAIPVFSI 130 Query: 425 HGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLK 604 HGNHDDP G G S+LDIL +TGLVNYF P +K G+S+++ Sbjct: 131 HGNHDDPSGDGRYSALDILQVTGLVNYFGRVPENDNIVVSPILLQKGFTKLALYGISNVR 190 Query: 605 DQRLSRLFAEKKVEMERPD 661 D+RL F E KV+ RPD Sbjct: 191 DERLYHSFRENKVKFLRPD 209 Score = 76.2 bits (179), Expect = 9e-13 Identities = 32/53 (60%), Positives = 45/53 (84%) Frame = +3 Query: 90 DDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 ++T+RILI+SD H+G+ E DPVRG DSF++F E+L +A + DVD+ILLGGD+F Sbjct: 15 ENTIRILISSDPHVGYGEKDPVRGNDSFVSFNEILEIARERDVDMILLGGDIF 67 Score = 45.6 bits (103), Expect = 0.002 Identities = 25/77 (32%), Positives = 39/77 (50%) Frame = +1 Query: 529 HVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFHLFVLHPNH 708 ++ +SP+LLQKG T+LALYG + + SF K F+L +H NH Sbjct: 166 NIVVSPILLQKGFTKLALYGISNVRDERLYHSFRENKVKFLRPDLYRDEWFNLLTVHQNH 225 Query: 709 ADRGHSNYIPEGVLPTF 759 + ++Y+PE + F Sbjct: 226 SAHTPTSYLPESFIQDF 242 >UniRef50_Q9C291 Cluster: Double-strand break repair protein mus-23; n=5; Pezizomycotina|Rep: Double-strand break repair protein mus-23 - Neurospora crassa Length = 760 Score = 117 bits (282), Expect = 3e-25 Identities = 58/139 (41%), Positives = 79/139 (56%), Gaps = 3/139 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT---VNYEDPNLNISYPILSIH 427 KPS M++ +RK+CLG KP +E LSD + F VNYEDP++N++ P+ SIH Sbjct: 83 KPSRKSMYQVMRSLRKHCLGMKPCELEFLSDAAEVFEGAFPFVNYEDPDINVAIPVFSIH 142 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 GNHDDP G G SLD+L GLVNYF P +K GLS+++D Sbjct: 143 GNHDDPSGDGHYCSLDLLQAAGLVNYFGRVPEADNIHVKPILLQKGRTKMALYGLSNVRD 202 Query: 608 QRLSRLFAEKKVEMERPDE 664 +R+ R F + KV RP++ Sbjct: 203 ERMHRTFRDNKVRFYRPNQ 221 Score = 67.3 bits (157), Expect = 4e-10 Identities = 27/54 (50%), Positives = 43/54 (79%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 DT+RIL+++D H+G+ E PVR +DS+ F+E++ +A + DVD++LLGGDLF + Sbjct: 28 DTIRILVSTDNHVGYAERHPVRKDDSWRTFDEIMQIAKKQDVDMVLLGGDLFHE 81 Score = 46.4 bits (105), Expect = 9e-04 Identities = 24/77 (31%), Positives = 37/77 (48%) Frame = +1 Query: 529 HVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFHLFVLHPNH 708 ++ + P+LLQKG T++ALYG + +F K F+L LH NH Sbjct: 177 NIHVKPILLQKGRTKMALYGLSNVRDERMHRTFRDNKVRFYRPNQQKNDWFNLLALHQNH 236 Query: 709 ADRGHSNYIPEGVLPTF 759 ++Y+ E +LP F Sbjct: 237 YAHTRTSYVAENMLPDF 253 >UniRef50_A1CU25 Cluster: Meiotic recombination protein Mre11; n=14; Pezizomycotina|Rep: Meiotic recombination protein Mre11 - Aspergillus clavatus Length = 816 Score = 116 bits (278), Expect = 9e-25 Identities = 56/137 (40%), Positives = 84/137 (61%), Gaps = 3/137 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT---VNYEDPNLNISYPILSIH 427 KPS M++ IR CLGDKP +E+LSD +NF VNYED ++N++ PI SIH Sbjct: 80 KPSRKSMYQVMRSIRMNCLGDKPCELEMLSDASENFQGAFNHVNYEDLDINVAIPIFSIH 139 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 GNHDDP G+G +++LD+L ++GL+NY+ P + +K G+S+++D Sbjct: 140 GNHDDPSGEGHLAALDLLQVSGLLNYYGRTPESDNIHIKPVLLQKGRTKLALYGMSNVRD 199 Query: 608 QRLSRLFAEKKVEMERP 658 +RL R F + KV+ +P Sbjct: 200 ERLFRTFRDGKVKFYQP 216 Score = 70.1 bits (164), Expect = 6e-11 Identities = 29/54 (53%), Positives = 44/54 (81%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 +T+RIL+A+D H+G+ E DP+RG+DS+ +F EV+ LA + DVD++LL GDLF + Sbjct: 25 ETIRILVATDNHVGYNERDPIRGDDSWKSFHEVMCLARERDVDMVLLAGDLFHE 78 Score = 49.6 bits (113), Expect = 9e-05 Identities = 28/77 (36%), Positives = 38/77 (49%) Frame = +1 Query: 529 HVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFHLFVLHPNH 708 ++ I PVLLQKG T+LALYG + F +F K + F+L +H NH Sbjct: 174 NIHIKPVLLQKGRTKLALYGMSNVRDERLFRTFRDGKVKFYQPSIQKNDWFNLMCVHQNH 233 Query: 709 ADRGHSNYIPEGVLPTF 759 + Y+PE LP F Sbjct: 234 HAYTETGYLPENFLPEF 250 >UniRef50_Q586P4 Cluster: Endo/exonuclease Mre11; n=3; Trypanosoma brucei|Rep: Endo/exonuclease Mre11 - Trypanosoma brucei Length = 763 Score = 113 bits (271), Expect = 7e-24 Identities = 59/138 (42%), Positives = 80/138 (57%), Gaps = 4/138 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSR----TVNYEDPNLNISYPILSI 424 KPS+ C+ + + ++R Y LGDKP+S LLSD +NF N++DPN+N++ PI I Sbjct: 92 KPSLGCLARTSSLLRSYVLGDKPISFTLLSDPKRNFPTHPVPLANFQDPNINVALPIFMI 151 Query: 425 HGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLK 604 HGNHDDPV G SS+DILS GLVNYF + + KK GL +++ Sbjct: 152 HGNHDDPV--GGTSSIDILSTAGLVNYFGHTSSLDDIVVEPVLLKKGDTYIALYGLGNVR 209 Query: 605 DQRLSRLFAEKKVEMERP 658 D RL R F KK+ +P Sbjct: 210 DDRLHRCFRMKKLHFVQP 227 Score = 57.6 bits (133), Expect = 4e-07 Identities = 31/63 (49%), Positives = 39/63 (61%), Gaps = 1/63 (1%) Frame = +3 Query: 96 TLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLA-VQCDVDLILLGGDLFDQLNLLSI 272 T + L+ SD HLG+ E D RG+DSF FEE L A ++ +VD ILL GD F N S+ Sbjct: 37 TFKFLVTSDNHLGYQERDSRRGDDSFTTFEECLRAARLEHEVDAILLAGDFFHD-NKPSL 95 Query: 273 VCL 281 CL Sbjct: 96 GCL 98 >UniRef50_Q9XGM2 Cluster: Double-strand break repair protein MRE11; n=14; Magnoliophyta|Rep: Double-strand break repair protein MRE11 - Arabidopsis thaliana (Mouse-ear cress) Length = 720 Score = 113 bits (271), Expect = 7e-24 Identities = 59/143 (41%), Positives = 83/143 (58%), Gaps = 8/143 (5%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT---VNYEDPNLNISYPILSIH 427 KPS + K EI+R++CL DKPV +++SDQ NF VNYEDP+ N+ P+ SIH Sbjct: 63 KPSRTTLVKAIEILRRHCLNDKPVQFQVVSDQTVNFQNAFGQVNYEDPHFNVGLPVFSIH 122 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYF----VNGPTTRT*EYHQYFCKKVLRGSPSMGLS 595 GNHDDP G ++S++DILS LVNYF + G + KK GL Sbjct: 123 GNHDDPAGVDNLSAIDILSACNLVNYFGKMVLGGSGVGQITLYPILMKKGSTTVALYGLG 182 Query: 596 HLKDQRLSRLF-AEKKVEMERPD 661 +++D+RL+R+F V+ RP+ Sbjct: 183 NIRDERLNRMFQTPHAVQWMRPE 205 Score = 73.7 bits (173), Expect = 5e-12 Identities = 32/54 (59%), Positives = 42/54 (77%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 DTLR+L+A+D HLG+ME D +R DSF AFEE+ S+A + VD +LLGGDLF + Sbjct: 8 DTLRVLVATDCHLGYMEKDEIRRHDSFKAFEEICSIAEEKQVDFLLLGGDLFHE 61 >UniRef50_Q6BL74 Cluster: Debaryomyces hansenii chromosome F of strain CBS767 of Debaryomyces hansenii; n=3; Saccharomycetales|Rep: Debaryomyces hansenii chromosome F of strain CBS767 of Debaryomyces hansenii - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 688 Score = 111 bits (266), Expect = 3e-23 Identities = 56/137 (40%), Positives = 79/137 (57%), Gaps = 3/137 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSR---TVNYEDPNLNISYPILSIH 427 KPS M+K + +R CLGD+P +ELL D + TVNYEDPN+NIS P+ +I Sbjct: 67 KPSKKSMYKVIKSLRTNCLGDRPCELELLGDPSMALGKDVDTVNYEDPNINISVPVFAIS 126 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 GNHDD G+G + LD+LS +GL+N+F P +K GL++++D Sbjct: 127 GNHDDATGEGFLLPLDLLSASGLINHFGKVPNNEELTVSPLIFQKGASKLALYGLANVRD 186 Query: 608 QRLSRLFAEKKVEMERP 658 +RL RLF + V+ RP Sbjct: 187 ERLHRLFRDGNVKFLRP 203 Score = 74.9 bits (176), Expect = 2e-12 Identities = 33/55 (60%), Positives = 44/55 (80%) Frame = +3 Query: 84 SPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 S DT+RILI +D H+G+ ENDP+RG+DS+ FEE+ S+A + DVD+IL GGDLF Sbjct: 9 SGPDTIRILITTDNHVGYNENDPIRGDDSWKTFEEITSIAKEKDVDMILQGGDLF 63 Score = 39.9 bits (89), Expect = 0.075 Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 3/88 (3%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGE---TR*NIGT 675 F K + + +SP++ QKG ++LALYG + F + GN + Sbjct: 153 FGKVPNNEELTVSPLIFQKGASKLALYGLANVRDERLHRLF---RDGNVKFLRPSSQADE 209 Query: 676 GFHLFVLHPNHADRGHSNYIPEGVLPTF 759 F++ +H NH ++Y+PE LP F Sbjct: 210 WFNILCVHQNHVPHTRTSYLPEQFLPKF 237 >UniRef50_Q9UVN9 Cluster: Double-strand break repair protein MRE11; n=2; Fungi/Metazoa group|Rep: Double-strand break repair protein MRE11 - Coprinus cinereus (Inky cap fungus) (Hormographiella aspergillata) Length = 731 Score = 103 bits (247), Expect = 5e-21 Identities = 61/152 (40%), Positives = 91/152 (59%), Gaps = 16/152 (10%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSD----QIKNFS-RTVNYEDPNLNISYPILS 421 KPS +C+++ ++R+Y LGDKP+ +ELLSD + FS +NYEDPN NIS P+ S Sbjct: 76 KPSRDCLYQTLALLREYTLGDKPIQVELLSDPDEGKAAGFSFPAINYEDPNFNISIPVFS 135 Query: 422 IHGNHDDPVG---QGSVSSLDILSITGLVNYF--VNGPTTRT*EYHQYFC-KKVL--RGS 577 IHGNHDDP G G++ +LD+LS++GL+NY + PT+ + VL +GS Sbjct: 136 IHGNHDDPQGPGVNGALCALDVLSVSGLLNYMGKFDLPTSDADAATTGIAVRPVLLRKGS 195 Query: 578 PSMGL---SHLKDQRLSRLFAEKKVEMERPDE 664 +G+ ++KDQR+ +V M P + Sbjct: 196 TKLGMYGVGNVKDQRMHFELRSNRVRMYMPKD 227 Score = 77.4 bits (182), Expect = 4e-13 Identities = 36/71 (50%), Positives = 51/71 (71%) Frame = +3 Query: 69 DISAWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 +I P+DT++IL+A+D H+G++E DP+RG+DS F E+L LAV+ +VD ILL GDLF Sbjct: 13 NIETADPEDTIKILLATDNHIGYLERDPIRGQDSINTFREILQLAVKNEVDFILLAGDLF 72 Query: 249 DQLNLLSIVCL 281 + N S CL Sbjct: 73 HE-NKPSRDCL 82 >UniRef50_A4HFW3 Cluster: Endo/exonuclease Mre11, putative; n=5; Trypanosomatidae|Rep: Endo/exonuclease Mre11, putative - Leishmania braziliensis Length = 863 Score = 103 bits (246), Expect = 7e-21 Identities = 54/143 (37%), Positives = 78/143 (54%), Gaps = 4/143 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSR----TVNYEDPNLNISYPILSI 424 KPS+ C+ + + RKY G+K V LLSD NF N++DPN+N++ P+ +I Sbjct: 60 KPSLGCLVRACSLFRKYVFGNKTVPFSLLSDAATNFPTHALPMANFQDPNINVALPVFAI 119 Query: 425 HGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLK 604 HGNHDDPV G SSLD+L+ G +NYF + + +K GL +++ Sbjct: 120 HGNHDDPV--GGTSSLDLLATNGYLNYFGHVTSLDDIILEPVLLRKGSTFIALYGLGNVR 177 Query: 605 DQRLSRLFAEKKVEMERPDETLG 673 D+RL R F KKV++ P G Sbjct: 178 DERLHRCFRLKKVQLVYPKPVPG 200 Score = 66.9 bits (156), Expect = 6e-10 Identities = 35/63 (55%), Positives = 43/63 (68%), Gaps = 1/63 (1%) Frame = +3 Query: 96 TLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLA-VQCDVDLILLGGDLFDQLNLLSI 272 T + L+ +D HLGF E DP RG+DSF FEEVL A + DVD +LLGGDLF + N S+ Sbjct: 5 TFKFLLTTDNHLGFAERDPRRGDDSFTTFEEVLRAARTEHDVDAMLLGGDLFHE-NKPSL 63 Query: 273 VCL 281 CL Sbjct: 64 GCL 66 >UniRef50_Q4P5A9 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 883 Score = 99 bits (238), Expect = 7e-20 Identities = 48/93 (51%), Positives = 67/93 (72%), Gaps = 9/93 (9%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQI------KNFSRTVNYEDPNLNISYPIL 418 KPS + + + ++R+Y LGDKP+S+ELLSD K F +NYEDPNLN++ P+ Sbjct: 164 KPSRDTLHQTMALLRQYTLGDKPISVELLSDPNDGALPGKRFP-AINYEDPNLNVAIPVF 222 Query: 419 SIHGNHDDPVG---QGSVSSLDILSITGLVNYF 508 SIHGNHDDP G G++S+LD+LS++GL+NYF Sbjct: 223 SIHGNHDDPQGVGETGALSALDLLSVSGLINYF 255 Score = 84.6 bits (200), Expect = 3e-15 Identities = 38/60 (63%), Positives = 49/60 (81%) Frame = +3 Query: 75 SAWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 +A S DD ++I++A+D H+G+ME DPVRG+DS FEE+L LAVQ DVDLILLGGDLF + Sbjct: 103 AAQSEDDHIKIMLATDNHIGYMERDPVRGQDSIRTFEEILQLAVQHDVDLILLGGDLFHE 162 Score = 35.9 bits (79), Expect = 1.2 Identities = 16/19 (84%), Positives = 17/19 (89%) Frame = +1 Query: 532 VRISPVLLQKGLTRLALYG 588 +RI PVLLQKG TRLALYG Sbjct: 285 IRIKPVLLQKGETRLALYG 303 >UniRef50_Q5KHA6 Cluster: Meiotic DNA double-strand break processing-related protein, putative; n=3; Fungi/Metazoa group|Rep: Meiotic DNA double-strand break processing-related protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 721 Score = 98.7 bits (235), Expect = 2e-19 Identities = 46/92 (50%), Positives = 66/92 (71%), Gaps = 8/92 (8%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKN----FS-RTVNYEDPNLNISYPILS 421 +PS CM + ++R++ LGDKP+ ELLSD + FS VNYEDPN+NI+ P+ S Sbjct: 86 RPSRTCMHQTIALLREFTLGDKPIEFELLSDPMDGSTPGFSFPAVNYEDPNINIAIPVFS 145 Query: 422 IHGNHDDPVG---QGSVSSLDILSITGLVNYF 508 IHGNHDDP G +G++ +LD+LS++G++NYF Sbjct: 146 IHGNHDDPQGTGPEGALCALDVLSVSGVLNYF 177 Score = 69.7 bits (163), Expect = 8e-11 Identities = 38/76 (50%), Positives = 48/76 (63%), Gaps = 2/76 (2%) Frame = +3 Query: 63 ENDISAWSPD--DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLG 236 E +S PD + RILIA+D H+G+ E DPVRG+DS F E+L LA DVD ILL Sbjct: 19 EPPLSIVEPDLENCFRILIATDNHIGYAEKDPVRGQDSINTFREILELARDHDVDFILLA 78 Query: 237 GDLFDQLNLLSIVCLN 284 GDLF + N S C++ Sbjct: 79 GDLFHE-NRPSRTCMH 93 Score = 37.5 bits (83), Expect = 0.40 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 3/75 (4%) Frame = +1 Query: 532 VRISPVLLQKGLTRLALYGT*PFKRSETFTSF-C*KKSGNGETR*NI--GTGFHLFVLHP 702 ++I PVLL+KG T +ALYG + + K T N+ F++ ++H Sbjct: 196 IQIRPVLLRKGTTHVALYGCGNIRDQRMYQELRANKVKMFMPTGGNVPDSDWFNILLVHQ 255 Query: 703 NHADRGHSNYIPEGV 747 N G NY+PE + Sbjct: 256 NRVRHGPQNYVPENM 270 >UniRef50_Q6ZBS2 Cluster: Putative DNA repair and meiosis protein Mre11; n=2; Oryza sativa|Rep: Putative DNA repair and meiosis protein Mre11 - Oryza sativa subsp. japonica (Rice) Length = 615 Score = 96.7 bits (230), Expect = 6e-19 Identities = 53/155 (34%), Positives = 86/155 (55%), Gaps = 8/155 (5%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQ---IKNFSRTVNYEDPNLNISYPILSIH 427 KPS++ + K EIIR YCL D V +++SDQ ++N VN+EDPN NI P+ ++H Sbjct: 69 KPSISTLVKSMEIIRSYCLNDHQVQFQVVSDQAACLQNRFGRVNFEDPNFNIGLPVFTVH 128 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYF--VNGPTTRT*EYH--QYFCKKVLRGSPSMGLS 595 G HD P G +S+ DILS VNYF V+ ++ + F KK GL Sbjct: 129 GTHDGPAGVDGLSATDILSACNFVNYFGKVDPGSSDVDQISVCPVFIKKGATSVALYGLG 188 Query: 596 HLKDQRLSRLF-AEKKVEMERPDETLGLGSIYLYY 697 +++D++LSR+ K++ + D ++++++ Sbjct: 189 NIRDEKLSRMLQTHYKIQWMKADSEDDWFNLFVFH 223 Score = 66.5 bits (155), Expect = 8e-10 Identities = 32/62 (51%), Positives = 44/62 (70%), Gaps = 2/62 (3%) Frame = +3 Query: 75 SAWSPDDT--LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 ++W ++ LRIL+A+D HLG++E D +R DSF FEE+ SLAV VD ILLGG+LF Sbjct: 6 ASWDEEENSMLRILVATDCHLGYLEKDEIRRFDSFDTFEEICSLAVINKVDFILLGGNLF 65 Query: 249 DQ 254 + Sbjct: 66 HE 67 >UniRef50_UPI00015B5FB6 Cluster: PREDICTED: similar to endo/exonuclease Mre11; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to endo/exonuclease Mre11 - Nasonia vitripennis Length = 450 Score = 96.3 bits (229), Expect = 8e-19 Identities = 50/141 (35%), Positives = 80/141 (56%), Gaps = 4/141 (2%) Frame = +2 Query: 260 PSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFS----RTVNYEDPNLNISYPILSIH 427 P +N + +C ++RKYCL DKP I+ L+D F+ + N++DP LNI PI +IH Sbjct: 80 PPLNVITRCISLLRKYCLSDKPAKIDCLTDPEWIFNHCPDKIANFKDPKLNIGMPIFAIH 139 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 G+ D P+ G V +LD+L+ TGL+NYF P +K + GL+H+ D Sbjct: 140 GHRDAPL-FGPVGALDLLAATGLINYFGKWPDKDKISIPPVLLRKGITTLALYGLNHMND 198 Query: 608 QRLSRLFAEKKVEMERPDETL 670 +L++ K+E+ + +ET+ Sbjct: 199 HKLTKCIKRDKLELLQ-EETI 218 Score = 48.4 bits (110), Expect = 2e-04 Identities = 24/57 (42%), Positives = 38/57 (66%) Frame = +3 Query: 90 DDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 ++ +++L+A+DI+LG+ E R +DSF FEE+L A +VD IL G+LF + N Sbjct: 24 ENIIQVLVAADINLGY-EQTVKREDDSFRTFEEILIYARDYEVDAILFAGNLFYEAN 79 >UniRef50_Q016A4 Cluster: Mre11 protein; n=3; Ostreococcus|Rep: Mre11 protein - Ostreococcus tauri Length = 1229 Score = 96.3 bits (229), Expect = 8e-19 Identities = 56/156 (35%), Positives = 84/156 (53%), Gaps = 19/156 (12%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTV--------------NYEDPN 394 KPS + +C +++R+ GD V IE+LSD +NF V NYEDP+ Sbjct: 531 KPSRETLVRCMDVLREATRGDGAVRIEVLSDTKENFPHRVHSPDGDVRPHAGIVNYEDPH 590 Query: 395 LNISYPILSIHGNHDDPVGQGSVSSLDILSITGLVNYF----VNGPTTRT*EYHQYFCKK 562 N+ P+ SIHGNHDDP G+ ++S++D+L+ G+VNYF + G T + +K Sbjct: 591 TNVELPVFSIHGNHDDPAGERNLSAMDVLASAGVVNYFGKHALAGGGTGNVDLKPVLLRK 650 Query: 563 VLRGSPSMGLSHLKDQRLSRLFAEKK-VEMERPDET 667 GL +++D RL ++F+ K V RP ET Sbjct: 651 GTTKVALYGLGYIRDNRLHQMFSVKGCVRWHRPAET 686 Score = 61.7 bits (143), Expect = 2e-08 Identities = 28/56 (50%), Positives = 39/56 (69%), Gaps = 1/56 (1%) Frame = +3 Query: 87 PD-DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 PD +TLR+L+A+D HLGF E D VR +D+F AFEE+ A + D + + GD+FD Sbjct: 473 PDPNTLRVLVATDTHLGFAERDAVRKDDAFAAFEEIFRHAREQKCDCVFMAGDVFD 528 >UniRef50_Q6CEM3 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 701 Score = 96.3 bits (229), Expect = 8e-19 Identities = 50/139 (35%), Positives = 74/139 (53%), Gaps = 3/139 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT---VNYEDPNLNISYPILSIH 427 KPS M++ +R C G++P +ELLSD +T +NYEDPN+N+S P+ +I Sbjct: 62 KPSRKSMYQVIRSLRMNCYGERPCELELLSDPTLALDQTFNHLNYEDPNINVSVPVFAIS 121 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 GNHDD G + D+L+ TGL+N+F +K GL++++D Sbjct: 122 GNHDDSGGDAMLCPNDVLAATGLINHFGRVTQNDQITVTPLLFRKGSTNLALYGLANVRD 181 Query: 608 QRLSRLFAEKKVEMERPDE 664 +RL R FA VE RP + Sbjct: 182 ERLFRTFASGNVEFLRPQD 200 Score = 65.7 bits (153), Expect = 1e-09 Identities = 28/52 (53%), Positives = 39/52 (75%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 DT+RILI +D H+G+ E DP+RG+DS+ F E++ LA DVD++L GDLF Sbjct: 7 DTIRILITTDNHVGYNEQDPIRGDDSWKTFHEIMGLARTEDVDMVLQAGDLF 58 Score = 43.6 bits (98), Expect = 0.006 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 2/87 (2%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGE--TR*NIGTG 678 F + T + ++P+L +KG T LALYG + F +F SGN E + Sbjct: 148 FGRVTQNDQITVTPLLFRKGSTNLALYGLANVRDERLFRTFA---SGNVEFLRPQDDQAW 204 Query: 679 FHLFVLHPNHADRGHSNYIPEGVLPTF 759 F L +H N A ++Y+P LP F Sbjct: 205 FSLLAVHQNRASHTETSYLPGNFLPQF 231 >UniRef50_A5DLP0 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 641 Score = 93.5 bits (222), Expect = 6e-18 Identities = 50/139 (35%), Positives = 71/139 (51%), Gaps = 3/139 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRT---VNYEDPNLNISYPILSIH 427 KPS +++ + +R CLGD+P +EL+SD + VNYED N NI P+ +I Sbjct: 67 KPSKKSLYQVIKSLRSNCLGDRPCELELISDPSMALTLDFPGVNYEDENFNIGVPVFAIS 126 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 GNHDD G + LDIL+ +GLVNYF KK G+ ++KD Sbjct: 127 GNHDDATGDSLLLPLDILAASGLVNYFGKVVNNEDITVAPLLFKKGTTKLALYGIGNVKD 186 Query: 608 QRLSRLFAEKKVEMERPDE 664 +RL R+F + K R + Sbjct: 187 ERLHRVFRDNKATFLRSSD 205 Score = 64.9 bits (151), Expect = 2e-09 Identities = 27/52 (51%), Positives = 40/52 (76%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 +T+ ILI +D H+G+ ENDP+RG+DS FEE+ +A + DVD+++ GGDLF Sbjct: 12 NTISILITTDNHVGYHENDPIRGDDSGKTFEEITRIAKERDVDMVVQGGDLF 63 Score = 46.0 bits (104), Expect = 0.001 Identities = 26/85 (30%), Positives = 40/85 (47%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFH 684 F K + + ++P+L +KG T+LALYG K F K+ + + F+ Sbjct: 153 FGKVVNNEDITVAPLLFKKGTTKLALYGIGNVKDERLHRVFRDNKATFLRSSDEPDSWFN 212 Query: 685 LFVLHPNHADRGHSNYIPEGVLPTF 759 +H NH ++YIPE LP F Sbjct: 213 FLCVHQNHVAHTRTSYIPENFLPKF 237 >UniRef50_P32829 Cluster: Double-strand break repair protein MRE11; n=9; Saccharomycetales|Rep: Double-strand break repair protein MRE11 - Saccharomyces cerevisiae (Baker's yeast) Length = 692 Score = 93.5 bits (222), Expect = 6e-18 Identities = 52/138 (37%), Positives = 75/138 (54%), Gaps = 4/138 (2%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSD--QIKNFSR--TVNYEDPNLNISYPILSI 424 KPS +++ + +R C+GDKP +ELLSD Q+ ++ VNYEDPN NIS P+ I Sbjct: 62 KPSKKSLYQVLKTLRLCCMGDKPCELELLSDPSQVFHYDEFTNVNYEDPNFNISIPVFGI 121 Query: 425 HGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLK 604 GNHDD G + +DIL TGL+N+F + + +K GL+ ++ Sbjct: 122 SGNHDDASGDSLLCPMDILHATGLINHFGKVIESDKIKVVPLLFQKGSTKLALYGLAAVR 181 Query: 605 DQRLSRLFAEKKVEMERP 658 D+RL R F + V E P Sbjct: 182 DERLFRTFKDGGVTFEVP 199 Score = 64.5 bits (150), Expect = 3e-09 Identities = 29/55 (52%), Positives = 41/55 (74%), Gaps = 1/55 (1%) Frame = +3 Query: 87 PD-DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 PD DT+RILI +D H+G+ ENDP+ G+DS+ F EV+ LA +VD+++ GDLF Sbjct: 4 PDPDTIRILITTDNHVGYNENDPITGDDSWKTFHEVMMLAKNNNVDMVVQSGDLF 58 Score = 44.8 bits (101), Expect = 0.003 Identities = 26/85 (30%), Positives = 40/85 (47%) Frame = +1 Query: 505 FCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFH 684 F K + +++ P+L QKG T+LALYG + F +F G F+ Sbjct: 149 FGKVIESDKIKVVPLLFQKGSTKLALYGLAAVRDERLFRTFKDGGVTFEVPTMREGEWFN 208 Query: 685 LFVLHPNHADRGHSNYIPEGVLPTF 759 L +H NH ++ ++PE LP F Sbjct: 209 LMCVHQNHTGHTNTAFLPEQFLPDF 233 >UniRef50_Q8SRV0 Cluster: DOUBLE-STRAND BREAK DNA REPAIR PROTEIN; n=1; Encephalitozoon cuniculi|Rep: DOUBLE-STRAND BREAK DNA REPAIR PROTEIN - Encephalitozoon cuniculi Length = 567 Score = 91.1 bits (216), Expect = 3e-17 Identities = 48/136 (35%), Positives = 76/136 (55%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNH 436 +PS +C+ + + R+YC+G++ + N + +N+ D N+ IS P++SIHGNH Sbjct: 54 RPSRSCLNRTIGLFRRYCIGNERSGLR------SNLA--LNFHDQNIGISIPVVSIHGNH 105 Query: 437 DDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKDQRL 616 DDP G VS +DIL GLVNY + + +K R + GL H+KD+RL Sbjct: 106 DDPSGISMVSPIDILQSAGLVNYIGKYNLIDRIDVYPLLLEKEYRVA-IYGLGHIKDRRL 164 Query: 617 SRLFAEKKVEMERPDE 664 R+F E ++ RP++ Sbjct: 165 YRMFCEGRIVFHRPED 180 Score = 64.5 bits (150), Expect = 3e-09 Identities = 33/62 (53%), Positives = 44/62 (70%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNLLSIVC 278 ++ILI SD HLG+ E+DPV +DS+ FEE+L +A + VDL+L GGDLF + N S C Sbjct: 1 MKILITSDNHLGYRESDPVLLDDSYDTFEEILGIAQRERVDLVLQGGDLFHE-NRPSRSC 59 Query: 279 LN 284 LN Sbjct: 60 LN 61 >UniRef50_Q23255 Cluster: Double-strand break repair protein mre-11; n=2; Caenorhabditis|Rep: Double-strand break repair protein mre-11 - Caenorhabditis elegans Length = 728 Score = 90.6 bits (215), Expect = 4e-17 Identities = 49/138 (35%), Positives = 74/138 (53%), Gaps = 4/138 (2%) Frame = +2 Query: 260 PSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTV----NYEDPNLNISYPILSIH 427 PS + T+++R+YCL P+++E LSD NF+++V NY D NLN+ PI +IH Sbjct: 120 PSREVQHRVTQLLRQYCLNGNPIALEFLSDASVNFNQSVFGHVNYYDQNLNVGLPIFTIH 179 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKD 607 GNHDD G+G +++LD+L +GLVN F + +K G+ +D Sbjct: 180 GNHDDLSGKG-LTALDLLHESGLVNLFGKHSNIQEFIVSPILLRKGETRLALYGIGSQRD 238 Query: 608 QRLSRLFAEKKVEMERPD 661 RL R F + RP+ Sbjct: 239 DRLVRAFKNNSISFLRPN 256 Score = 58.8 bits (136), Expect = 2e-07 Identities = 28/57 (49%), Positives = 39/57 (68%) Frame = +3 Query: 90 DDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 +D ++IL+A+DIH G+ EN D+ FEEVL +A + VD+ILLGGDLF + N Sbjct: 63 EDIIKILVATDIHCGYGENKANIHMDAVNTFEEVLQIATEQKVDMILLGGDLFHENN 119 Score = 49.6 bits (113), Expect = 9e-05 Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 6/92 (6%) Frame = +1 Query: 502 LFCKWTDYTHVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTG- 678 LF K ++ +SP+LL+KG TRLALYG + +F K + R N G Sbjct: 204 LFGKHSNIQEFIVSPILLRKGETRLALYGIGSQRDDRLVRAF--KNNSISFLRPNAGAED 261 Query: 679 -FHLFVLHPNHADRG-H---SNYIPEGVLPTF 759 F+LFVLH N R H N++PE ++P F Sbjct: 262 WFNLFVLHQNRPRRAMHRSTGNFLPESLIPQF 293 >UniRef50_A3FQD2 Cluster: DNA repair and meiosis protein Mre11; n=2; Cryptosporidium|Rep: DNA repair and meiosis protein Mre11 - Cryptosporidium parvum Iowa II Length = 513 Score = 87.4 bits (207), Expect = 4e-16 Identities = 45/133 (33%), Positives = 67/133 (50%) Frame = +2 Query: 275 MFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNHDDPVGQ 454 M+K IIR+YC+G+K + L+ Q + N+E + N+S P IHGNHDDP + Sbjct: 1 MYKVMNIIREYCMGNKQIKFRALNRQDSSNVNGYNWEVGDANVSIPFFGIHGNHDDPGEE 60 Query: 455 GSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKDQRLSRLFAE 634 G +S LDIL +NY E +K G+ +++D+RL R F + Sbjct: 61 GLLSPLDILESARFINYIGKNNNVDNIEVFPVLLEKGSTRLAIYGIGNIRDERLHRSFEK 120 Query: 635 KKVEMERPDETLG 673 KV+ P+ T G Sbjct: 121 NKVKFLIPENTNG 133 >UniRef50_Q0MR25 Cluster: MRE11-like protein; n=1; Penicillium marneffei|Rep: MRE11-like protein - Penicillium marneffei Length = 731 Score = 87.4 bits (207), Expect = 4e-16 Identities = 39/95 (41%), Positives = 62/95 (65%) Frame = +2 Query: 374 VNYEDPNLNISYPILSIHGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYF 553 VNYED ++N++ P+ SIHGNHDDP G+G +++LDIL ++GL+NY+ P + + Sbjct: 93 VNYEDLDINVAIPVFSIHGNHDDPSGEGHLAALDILQVSGLLNYYGRTPESDNIQVKPVL 152 Query: 554 CKKVLRGSPSMGLSHLKDQRLSRLFAEKKVEMERP 658 +K GLS+++D+RL R F + KV+ +P Sbjct: 153 LQKGRTKLALYGLSNVRDERLFRTFRDGKVKFFQP 187 Score = 73.3 bits (172), Expect = 7e-12 Identities = 34/75 (45%), Positives = 51/75 (68%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNLLSI 272 DT+RIL+++D H+G+ E DP+RG+DS+ F E++ LA + DVD++LL GDLF + N + Sbjct: 14 DTIRILVSTDNHVGYNERDPIRGDDSWKTFHEIMCLAKERDVDMVLLAGDLFHENNHPAN 73 Query: 273 VCLNVQK*SANIVLG 317 C+ A IV G Sbjct: 74 PCIKSCAPYAQIVWG 88 Score = 48.8 bits (111), Expect = 2e-04 Identities = 27/77 (35%), Positives = 39/77 (50%) Frame = +1 Query: 529 HVRISPVLLQKGLTRLALYGT*PFKRSETFTSFC*KKSGNGETR*NIGTGFHLFVLHPNH 708 ++++ PVLLQKG T+LALYG + F +F K + F+L +H NH Sbjct: 145 NIQVKPVLLQKGRTKLALYGLSNVRDERLFRTFRDGKVKFFQPSVQKEDWFNLICVHQNH 204 Query: 709 ADRGHSNYIPEGVLPTF 759 + Y+PE LP F Sbjct: 205 HAYTETGYLPENFLPEF 221 >UniRef50_A5YZR9 Cluster: MRE11B; n=2; Magnoliophyta|Rep: MRE11B - Zea mays (Maize) Length = 672 Score = 83.8 bits (198), Expect = 5e-15 Identities = 49/133 (36%), Positives = 71/133 (53%), Gaps = 7/133 (5%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQ---IKNFSRTVNYEDPNLNISYPILSIH 427 KPS + + K EI+R+YC+ D PV +++SDQ ++N VNYEDPN I P+ +IH Sbjct: 138 KPSNSTLVKAIEILRRYCMNDCPVQFQVISDQAASLQNRFCQVNYEDPNYKIGLPVFTIH 197 Query: 428 GNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPS----MGLS 595 G+ D P G ++S DIL+ +NYF T V+R + GL Sbjct: 198 GDQDYPTGTDNLSVNDILTAGNFLNYFGKTDLGCTGVGKVTVYPVVIRKGETYIAMYGLG 257 Query: 596 HLKDQRLSRLFAE 634 ++KD RL R+ E Sbjct: 258 NIKDGRLKRMLHE 270 Score = 66.5 bits (155), Expect = 8e-10 Identities = 30/54 (55%), Positives = 42/54 (77%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 ++LR+L+A+D HLG++E D VRG DSF FEE+ SLAV+ VD +LL G+LF + Sbjct: 83 NSLRVLVATDCHLGYLEKDEVRGFDSFDTFEEICSLAVKNKVDFLLLCGNLFHE 136 >UniRef50_Q22G12 Cluster: Ser/Thr protein phosphatase family protein; n=1; Tetrahymena thermophila SB210|Rep: Ser/Thr protein phosphatase family protein - Tetrahymena thermophila SB210 Length = 884 Score = 76.2 bits (179), Expect = 9e-13 Identities = 37/76 (48%), Positives = 49/76 (64%) Frame = +3 Query: 90 DDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNLLS 269 ++T +IL+A+D H+G+ ENDP+RG DSF AFEEVL +A VD +LLGGDLF + N Sbjct: 21 ENTFKILVATDNHVGYKENDPIRGNDSFEAFEEVLKIAKSEKVDFLLLGGDLFHETNPSQ 80 Query: 270 IVCLNVQK*SANIVLG 317 + N VLG Sbjct: 81 QCLYKMLNLLGNYVLG 96 Score = 74.5 bits (175), Expect = 3e-12 Identities = 45/138 (32%), Positives = 72/138 (52%), Gaps = 1/138 (0%) Frame = +2 Query: 254 TKPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGN 433 T PS C++K ++ Y LGD E+L I N++ VN++D NLNI PI IHGN Sbjct: 76 TNPSQQCLYKMLNLLGNYVLGDG----EILYG-ISNYN-DVNFQDCNLNIELPIFVIHGN 129 Query: 434 HDDPVGQ-GSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKDQ 610 HD P + G++S +D+L T +N+F + +K G+ +LKD+ Sbjct: 130 HDYPSDEYGNLSVIDLLHATKYLNHFGKFSNIEQIKVTPIIFQKGNTTVALYGIGYLKDK 189 Query: 611 RLSRLFAEKKVEMERPDE 664 ++ E K+E +P++ Sbjct: 190 YFHKMLEEGKIEFVKPEQ 207 >UniRef50_Q86C23 Cluster: Mre11; n=2; Entamoeba histolytica|Rep: Mre11 - Entamoeba histolytica Length = 603 Score = 69.3 bits (162), Expect = 1e-10 Identities = 54/175 (30%), Positives = 84/175 (48%), Gaps = 13/175 (7%) Frame = +2 Query: 260 PSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNHD 439 PS C+ K E++RKY +G S ++ N + N N I YP+ IHGNHD Sbjct: 62 PSKYCLTKTMELMRKYLMGKPKNSFDVAYTYEHN--QEDNGFSMNQGIKYPMYVIHGNHD 119 Query: 440 DPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSM----------- 586 P G V+ LDIL GLVN+ G E + +L SP + Sbjct: 120 IPSGIEHVAGLDILQTAGLVNFI--GKAEDISEIDNKTDQTILHLSPILLQKGTTRIALY 177 Query: 587 GLSHLKDQRLSRLFAEKKVEMERPDETLGLGSIY--LYYIQIMLTEDTVTIFQKE 745 G+S+ K++ ++RL+A +V+++ PD G ++ L Q + +T+T F +E Sbjct: 178 GMSYKKNEEMNRLWASSQVQIDEPD-----GDVFKILLIHQDRILRNTLTTFPEE 227 Score = 57.2 bits (132), Expect = 5e-07 Identities = 29/56 (51%), Positives = 35/56 (62%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 +T +ILI SD HLG E +D ++AFEE+L A Q DVDLIL GD FD N Sbjct: 6 NTFKILICSDTHLGAGEKSHCLKDDCYLAFEEILQQANQEDVDLILHSGDFFDDQN 61 >UniRef50_UPI000049A054 Cluster: DNA repair protein rad32; n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA repair protein rad32 - Entamoeba histolytica HM-1:IMSS Length = 550 Score = 68.5 bits (160), Expect = 2e-10 Identities = 28/83 (33%), Positives = 50/83 (60%) Frame = +2 Query: 257 KPSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNH 436 +P+ +C+ K +I+KYC+GD + + + S +N DP +N+ +P+ +IHG + Sbjct: 56 RPNKSCVSKTANLIKKYCIGDADIPYTIKDEA--ELSYPLNITDPYINVKHPLFTIHGTN 113 Query: 437 DDPVGQGSVSSLDILSITGLVNY 505 D+P G ++ +IL+ GLVNY Sbjct: 114 DEPSGYKLIAGSEILASCGLVNY 136 Score = 36.7 bits (81), Expect = 0.70 Identities = 17/54 (31%), Positives = 29/54 (53%) Frame = +3 Query: 96 TLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQL 257 ++ + D HLG+ E + +D + FE+ L A Q + ++L GDLF+ L Sbjct: 2 SITFFVTGDNHLGYYEKNLTLKDDCYKLFEQYLKEATQKEGSILLQCGDLFNDL 55 >UniRef50_Q4U965 Cluster: Double-strand break repair protein, putative; n=2; Theileria|Rep: Double-strand break repair protein, putative - Theileria annulata Length = 870 Score = 65.7 bits (153), Expect = 1e-09 Identities = 32/72 (44%), Positives = 44/72 (61%) Frame = +3 Query: 39 SCTSKIMIENDISAWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDV 218 S SK D+ D+ ++IL+ +D HLG+ E+DP RG DS FEE+L +A +V Sbjct: 244 SDVSKEFEFKDLDESEDDNVVKILVFTDTHLGYKEDDPFRGNDSLNTFEELLFIAKHLEV 303 Query: 219 DLILLGGDLFDQ 254 D IL GDLFD+ Sbjct: 304 DFILHSGDLFDK 315 Score = 54.0 bits (124), Expect = 4e-06 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Frame = +2 Query: 410 PILSIHGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCK--KVLRGSPS 583 P IHGNHD+P Q S+S +DIL + GLV YF R + K K+ +G Sbjct: 394 PFFVIHGNHDNPTYQHSLSPIDILDVAGLVTYF-----GRVFDLENVVIKPIKISKGDVK 448 Query: 584 M---GLSHLKDQRLSRLFAEKKVEMERPDE 664 + GL +KD+RL +F + V+ E+ +E Sbjct: 449 IALYGLGWIKDERLVEMFNKNMVKFEQCEE 478 >UniRef50_Q7RBG7 Cluster: Rad32-related; n=6; Plasmodium (Vinckeia)|Rep: Rad32-related - Plasmodium yoelii yoelii Length = 1037 Score = 63.7 bits (148), Expect = 5e-09 Identities = 27/52 (51%), Positives = 41/52 (78%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 DTL+IL+ +D HLG+ EN+P++ +D+F FEE+L +A + +VD+IL GDLF Sbjct: 303 DTLKILLCTDNHLGYKENNPIQKKDTFNTFEEILFIAKKLNVDMILNSGDLF 354 Score = 44.4 bits (100), Expect = 0.003 Identities = 27/87 (31%), Positives = 40/87 (45%) Frame = +2 Query: 404 SYPILSIHGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPS 583 S P +IHGNHD P + LDIL+I+ L+NY + KK S Sbjct: 536 SIPFYTIHGNHDYPYSYDYICPLDILNISNLINYIGKNNMEKLIIKPILLNKKGTHIS-I 594 Query: 584 MGLSHLKDQRLSRLFAEKKVEMERPDE 664 + +KD+RL F K ++ P++ Sbjct: 595 YAIGWIKDERLYNYFENKNIKFIIPED 621 >UniRef50_A5K9T7 Cluster: DNA repair exonuclease, putative; n=1; Plasmodium vivax|Rep: DNA repair exonuclease, putative - Plasmodium vivax Length = 1119 Score = 63.3 bits (147), Expect = 7e-09 Identities = 32/63 (50%), Positives = 44/63 (69%) Frame = +3 Query: 60 IENDISAWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGG 239 I +S PD TL+IL+ +D HLG+ EN+ V+ ED+F +FEE+L +A +VDLIL G Sbjct: 295 IRKSLSKNEPD-TLKILLCTDNHLGYKENNAVQKEDTFNSFEEILFVAKHLNVDLILNSG 353 Query: 240 DLF 248 DLF Sbjct: 354 DLF 356 Score = 50.0 bits (114), Expect = 7e-05 Identities = 28/85 (32%), Positives = 39/85 (45%) Frame = +2 Query: 410 PILSIHGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMG 589 P+ ++HGNHD P +S LDIL + L+NY R K Sbjct: 549 PLFTMHGNHDYPYSCDYISPLDILHVGNLINYIGKSSLDRI-VIKPVLLNKEETKIAIYA 607 Query: 590 LSHLKDQRLSRLFAEKKVEMERPDE 664 + +KD+RL R F EKKV+ P + Sbjct: 608 IGWIKDERLHRAFEEKKVKFMLPSD 632 >UniRef50_A2ECB0 Cluster: Ser/Thr protein phosphatase, putative; n=1; Trichomonas vaginalis G3|Rep: Ser/Thr protein phosphatase, putative - Trichomonas vaginalis G3 Length = 562 Score = 62.9 bits (146), Expect = 9e-09 Identities = 37/135 (27%), Positives = 66/135 (48%) Frame = +2 Query: 260 PSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNHD 439 PS + K +I+ ++ +G L S+ + S N+ +PN+NI P +HGNHD Sbjct: 63 PSRYAVIKTMKILDEFVIGQGNPPEILYSEGL---SSDPNWLNPNINIKIPFFCMHGNHD 119 Query: 440 DPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKDQRLS 619 P G GS S + +LS++ +N+F T E K+ GL ++ +++ Sbjct: 120 APNGLGSTSPIQLLSVSKYLNFFKPVDIKETIELQPIVLKRGTIRVVVYGLGYIFEEKFK 179 Query: 620 RLFAEKKVEMERPDE 664 + KK+++ P+E Sbjct: 180 EVVMGKKLKLIAPEE 194 Score = 51.2 bits (117), Expect = 3e-05 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = +3 Query: 84 SPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNL 263 S DT +I I +D H+G+ E D + +DSF AF+E + A + D+IL GD F++ N Sbjct: 4 SQQDTFKIAIFTDTHIGYDEQDAITEKDSFRAFKECVQNAHIQNADIILHAGDFFNERNP 63 Query: 264 LSIVCLNVQK*SANIVLG 317 + K V+G Sbjct: 64 SRYAVIKTMKILDEFVIG 81 >UniRef50_A0DUM4 Cluster: Chromosome undetermined scaffold_64, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_64, whole genome shotgun sequence - Paramecium tetraurelia Length = 1041 Score = 62.1 bits (144), Expect = 2e-08 Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 2/137 (1%) Frame = +2 Query: 260 PSVNCMFKCTEIIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNHD 439 P+ +C+ KC +I++++ GD I++ ++ + + N+ N N+ PI I+GNHD Sbjct: 438 PTEHCLLKCVDILQRHVFGDNFGGIQM---EVNSLNYQPNFSCSNFNVQLPIFIINGNHD 494 Query: 440 DPVGQ--GSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMGLSHLKDQR 613 D V + SVS LDIL + +NY K + GL ++KD + Sbjct: 495 DIVTERNESVSILDILHESKYLNYIGKITDQSNVCIKPIVLVKNNQKIALYGLGYMKDYQ 554 Query: 614 LSRLFAEKKVEMERPDE 664 L ++ E K+ ++ DE Sbjct: 555 LHKIINEGKLVLDSLDE 571 Score = 53.2 bits (122), Expect = 8e-06 Identities = 28/54 (51%), Positives = 37/54 (68%), Gaps = 3/54 (5%) Frame = +3 Query: 102 RILIASDIHLGFMEN---DPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 + L+ASD HLG EN R +D+F AFEEVL +A Q +VD ++LGGDLF + Sbjct: 382 KFLVASDNHLGANENVGPKSNRYQDAFDAFEEVLQIASQQNVDFVILGGDLFHE 435 >UniRef50_Q8I263 Cluster: DNA repair exonuclease, putative; n=1; Plasmodium falciparum 3D7|Rep: DNA repair exonuclease, putative - Plasmodium falciparum (isolate 3D7) Length = 1118 Score = 59.7 bits (138), Expect = 9e-08 Identities = 26/51 (50%), Positives = 40/51 (78%) Frame = +3 Query: 96 TLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 TL+IL+ +D HLG+ EN+ ++ +DSF +FEE+L +A + +VD+IL GDLF Sbjct: 350 TLKILLCTDNHLGYKENNSIQKKDSFNSFEEILFIAKKLNVDMILNSGDLF 400 Score = 44.8 bits (101), Expect = 0.003 Identities = 26/85 (30%), Positives = 38/85 (44%) Frame = +2 Query: 410 PILSIHGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSMG 589 P +IHGNHD P +S LDIL+I+ L+NY + K Sbjct: 583 PFYTIHGNHDYPYSYEYISPLDILNISNLINY-IGKNNLNNIVVKPILLNKYKSKISIYA 641 Query: 590 LSHLKDQRLSRLFAEKKVEMERPDE 664 + +KD+RL R F +V+ P + Sbjct: 642 VGWMKDERLYRSFENNEVKFILPSD 666 >UniRef50_A7AP02 Cluster: DNA repair protein (Mre11) family protein; n=1; Babesia bovis|Rep: DNA repair protein (Mre11) family protein - Babesia bovis Length = 1040 Score = 59.7 bits (138), Expect = 9e-08 Identities = 30/51 (58%), Positives = 34/51 (66%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 LR +I +D HLG E DP+R DSF AF+EVL LA VD IL GDLFD Sbjct: 207 LRFMIFTDTHLGHKETDPIRENDSFNAFQEVLFLAKYLQVDGILHAGDLFD 257 Score = 51.6 bits (118), Expect = 2e-05 Identities = 38/147 (25%), Positives = 67/147 (45%), Gaps = 11/147 (7%) Frame = +2 Query: 260 PSVNCMFKCTEIIRKYC-----LGDKPVSIEL-LSDQIKNFSR---TVNYEDPNLN--IS 406 PS + +++ E++R+YC P++I L S +++ ++ + + D + Sbjct: 261 PSRSVIYRTMELLRRYCRKSDLTSPLPLNIRLPKSCAVRSETKRLEALKFIDGTITKEAR 320 Query: 407 YPILSIHGNHDDPVGQGSVSSLDILSITGLVNYFVNGPTTRT*EYHQYFCKKVLRGSPSM 586 P IHGNHD+P +S +D+L ++GLV +F E H K Sbjct: 321 VPFFVIHGNHDNPTTMNGLSPIDLLDVSGLVTFFGTVTDMTKVEVHPICISKGDIHLALY 380 Query: 587 GLSHLKDQRLSRLFAEKKVEMERPDET 667 G+ +K++ L + F E KV P T Sbjct: 381 GMGWVKEEFLYKAFEENKVVFVPPVNT 407 >UniRef50_Q8PUY5 Cluster: DNA double-strand break repair protein mre11; n=2; Methanosarcina|Rep: DNA double-strand break repair protein mre11 - Methanosarcina mazei (Methanosarcina frisia) Length = 617 Score = 49.6 bits (113), Expect = 9e-05 Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 1/58 (1%) Frame = +3 Query: 90 DDTLRILIASDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 D +RIL +D HLG+ + + VR +D F AFE V+ AV VD ++ GDLFD N Sbjct: 2 DREIRILHTADTHLGYRQYHSEVRRQDFFKAFETVIKDAVDMQVDAVVHAGDLFDSRN 59 >UniRef50_Q46FJ9 Cluster: DNA repair protein; n=1; Methanosarcina barkeri str. Fusaro|Rep: DNA repair protein - Methanosarcina barkeri (strain Fusaro / DSM 804) Length = 776 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/55 (45%), Positives = 35/55 (63%), Gaps = 1/55 (1%) Frame = +3 Query: 99 LRILIASDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 +RIL +D HLG+ + + VR D F AFE V++ AV+ VD ++ GDLFD N Sbjct: 5 IRILHTADTHLGYRQYHSEVRRNDFFAAFELVVNDAVEMQVDAVVHAGDLFDSRN 59 >UniRef50_Q2JK75 Cluster: Ser/Thr protein phosphatase family protein; n=4; Synechococcus|Rep: Ser/Thr protein phosphatase family protein - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 430 Score = 45.2 bits (102), Expect = 0.002 Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 2/54 (3%) Frame = +3 Query: 96 TLRILIASDIHLGFMEND-PVRGEDSFIAFEEVLS-LAVQCDVDLILLGGDLFD 251 T L +D+HLG+ D P R +D F+AF +V+ A+Q VD +L+ GDLF+ Sbjct: 5 TCTFLHLADVHLGYDRYDSPERSKDFFLAFRDVVRRYAIQDPVDFVLIAGDLFE 58 >UniRef50_A4ENU6 Cluster: Putative ATP-dependent dsDNA exonuclease; n=2; Rhodobacteraceae|Rep: Putative ATP-dependent dsDNA exonuclease - Roseobacter sp. SK209-2-6 Length = 380 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/52 (40%), Positives = 32/52 (61%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 +RIL +D+HLG N ED E++LS V DVD++++ GD+FD+ Sbjct: 1 MRILHTADLHLGRQFNGISLEEDHAAILEQILSAVVAHDVDVLIIAGDIFDR 52 >UniRef50_A3HX94 Cluster: DNA repair exonuclease; n=1; Algoriphagus sp. PR1|Rep: DNA repair exonuclease - Algoriphagus sp. PR1 Length = 414 Score = 45.2 bits (102), Expect = 0.002 Identities = 22/54 (40%), Positives = 34/54 (62%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 ++IL +D HLG + R E+ + EE++ +A Q +VDL+LL GD+FD N Sbjct: 2 IKILHTADWHLGKRLQEFSRIEEQKLVLEEIIEVADQENVDLVLLAGDIFDTFN 55 >UniRef50_Q8DMQ1 Cluster: Tll0060 protein; n=1; Synechococcus elongatus|Rep: Tll0060 protein - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 428 Score = 44.0 bits (99), Expect = 0.005 Identities = 22/56 (39%), Positives = 36/56 (64%), Gaps = 4/56 (7%) Frame = +3 Query: 99 LRILIASDIHLGF---MENDPVRGEDSFIAFEEVL-SLAVQCDVDLILLGGDLFDQ 254 +R L +D+HLG+ +++P R D F AF+ L + A+Q VD +L+ GDLF++ Sbjct: 2 VRFLHVADVHLGYNKYRQDNPSRMLDFFRAFDSALETYAIQAQVDFVLIAGDLFEE 57 >UniRef50_A5YS39 Cluster: DNA double-strand break repair protein mre11; n=1; uncultured haloarchaeon|Rep: DNA double-strand break repair protein mre11 - uncultured haloarchaeon Length = 397 Score = 43.6 bits (98), Expect = 0.006 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 1/53 (1%) Frame = +3 Query: 96 TLRILIASDIHLGFMEND-PVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 T IL SD HLG + + VR +D AF++ +S+A+Q DVD ++ GDLFD Sbjct: 11 TTTILHISDTHLGNRQYEYDVRRDDFSDAFDQSVSIAIQEDVDAVIHTGDLFD 63 >UniRef50_Q8U1N9 Cluster: DNA double-strand break repair protein mre11; n=4; Thermococcaceae|Rep: DNA double-strand break repair protein mre11 - Pyrococcus furiosus Length = 426 Score = 43.6 bits (98), Expect = 0.006 Identities = 22/45 (48%), Positives = 31/45 (68%), Gaps = 1/45 (2%) Frame = +3 Query: 117 SDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 +DIHLG+ + + P R E+ AF+ L +AVQ +VD IL+ GDLF Sbjct: 7 ADIHLGYEQFHKPQREEEFAEAFKNALEIAVQENVDFILIAGDLF 51 >UniRef50_Q12VW7 Cluster: Metallophosphoesterase; n=1; Methanococcoides burtonii DSM 6242|Rep: Metallophosphoesterase - Methanococcoides burtonii (strain DSM 6242) Length = 485 Score = 43.2 bits (97), Expect = 0.008 Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Frame = +3 Query: 99 LRILIASDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 +RIL D H+G+ + + VR +D AF V+ A+ VD+++ GDLFD N Sbjct: 5 IRILHTGDTHIGYRQYHSEVRRQDFIDAFSSVIDDAIDMKVDVVVHAGDLFDSRN 59 >UniRef50_Q3ISN6 Cluster: Conserved DNA repair operon protein; n=1; Natronomonas pharaonis DSM 2160|Rep: Conserved DNA repair operon protein - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 451 Score = 42.7 bits (96), Expect = 0.011 Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%) Frame = +3 Query: 102 RILIASDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 R+L D H+G+ + + P R ED AF +V AV+ DVD ++ GDLF Sbjct: 3 RVLHTGDTHIGYRQYHTPERREDFLSAFRQVADDAVEMDVDAVVHAGDLF 52 >UniRef50_A2BM15 Cluster: Predicted DNA repair exonuclease; n=1; Hyperthermus butylicus DSM 5456|Rep: Predicted DNA repair exonuclease - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 407 Score = 42.3 bits (95), Expect = 0.014 Identities = 21/52 (40%), Positives = 32/52 (61%), Gaps = 1/52 (1%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGE-DSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 L +L SD HLG+ + + E D + FEEV+ +A++ VD ++ GDLFD Sbjct: 11 LHLLHVSDTHLGYRQYGIIEREMDFYQVFEEVIDIAIREHVDAVIHTGDLFD 62 >UniRef50_O29231 Cluster: DNA double-strand break repair protein mre11; n=1; Archaeoglobus fulgidus|Rep: DNA double-strand break repair protein mre11 - Archaeoglobus fulgidus Length = 443 Score = 41.1 bits (92), Expect = 0.033 Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 1/45 (2%) Frame = +3 Query: 117 SDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 +D+HLG+ + N P R ED AF+ + AV+ + D +++ GDLF Sbjct: 7 ADVHLGYEQYNQPWRAEDFAKAFKVIAEKAVESNADFVVIAGDLF 51 >UniRef50_A0RW71 Cluster: DNA repair exonuclease; n=1; Cenarchaeum symbiosum|Rep: DNA repair exonuclease - Cenarchaeum symbiosum Length = 417 Score = 39.9 bits (89), Expect = 0.075 Identities = 19/50 (38%), Positives = 31/50 (62%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 +R ASDIHLGF + ++G + + FE+V+ + VD +L+ GD+F Sbjct: 1 MRFAHASDIHLGFQDGAALQGIEREV-FEKVIDGCISRKVDFVLMPGDIF 49 >UniRef50_Q9X1X0 Cluster: Exonuclease, putative; n=3; Thermotoga|Rep: Exonuclease, putative - Thermotoga maritima Length = 385 Score = 38.7 bits (86), Expect = 0.17 Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 4/66 (6%) Frame = +3 Query: 99 LRILIASDIHLG---FMENDPV-RGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNLL 266 L+IL SD HLG + + PV R E+ A ++V+ A + +VDLILL GDL N Sbjct: 7 LKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNP 66 Query: 267 SIVCLN 284 S+V L+ Sbjct: 67 SVVALH 72 >UniRef50_O67727 Cluster: ATP-dependent dsDNA exonuclease; n=1; Aquifex aeolicus|Rep: ATP-dependent dsDNA exonuclease - Aquifex aeolicus Length = 379 Score = 38.7 bits (86), Expect = 0.17 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 +R++ SDIH G R ED A +V+ + DL+L+ GD+FD+ N Sbjct: 1 MRLIHLSDIHAGKNLGRVSRNEDVVYALNQVVDFCKENKPDLVLVAGDVFDKAN 54 >UniRef50_Q9UZC9 Cluster: DNA double-strand break repair protein mre11; n=1; Pyrococcus abyssi|Rep: DNA double-strand break repair protein mre11 - Pyrococcus abyssi Length = 423 Score = 38.7 bits (86), Expect = 0.17 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%) Frame = +3 Query: 117 SDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 +D+HLG+ + N R E+ AFE+ + + V VD I++ GDLF+ Sbjct: 17 ADVHLGYEQFNRSQRAEEFAKAFEDAIKICVDEKVDFIVIAGDLFN 62 >UniRef50_Q3A5P7 Cluster: DNA repair exonuclease; n=1; Pelobacter carbinolicus DSM 2380|Rep: DNA repair exonuclease - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 370 Score = 38.3 bits (85), Expect = 0.23 Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 5/55 (9%) Frame = +3 Query: 99 LRILIASDIHLGFM-----ENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 +RIL +DIHLG + E R D AFE ++ LA+ V L+++ GDLF Sbjct: 2 IRILHTADIHLGAVFAELAECAAARRNDQLYAFERMVELAIDRKVHLLVVAGDLF 56 >UniRef50_UPI00015BCD31 Cluster: UPI00015BCD31 related cluster; n=1; unknown|Rep: UPI00015BCD31 UniRef100 entry - unknown Length = 380 Score = 37.9 bits (84), Expect = 0.30 Identities = 18/52 (34%), Positives = 28/52 (53%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 ++ L DIH G + R +D+ A +V+ + VD IL+ GD+FDQ Sbjct: 2 IKFLHIGDIHAGKTLHSRSRNDDAEYAISQVIDFVKKEPVDFILMAGDIFDQ 53 >UniRef50_A7DNM9 Cluster: Metallophosphoesterase; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Metallophosphoesterase - Candidatus Nitrosopumilus maritimus SCM1 Length = 415 Score = 37.9 bits (84), Expect = 0.30 Identities = 18/44 (40%), Positives = 28/44 (63%) Frame = +3 Query: 117 SDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 SDIHLGF + ++ + + FEEV+ ++ VD +L+ GDLF Sbjct: 8 SDIHLGFQDKKELQKIEQEV-FEEVVCTCIKQKVDFVLITGDLF 50 >UniRef50_Q2AI56 Cluster: Exonuclease SbcD; n=1; Halothermothrix orenii H 168|Rep: Exonuclease SbcD - Halothermothrix orenii H 168 Length = 435 Score = 37.5 bits (83), Expect = 0.40 Identities = 21/54 (38%), Positives = 30/54 (55%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 LRIL +D HLG R E+ EE++ +A VD++L+ GD+FD N Sbjct: 27 LRILHTADWHLGKHLEGWSRYEEQKEFVEEIIEIADDNKVDMVLICGDIFDTTN 80 >UniRef50_UPI00015BAD8F Cluster: metallophosphoesterase; n=1; Ignicoccus hospitalis KIN4/I|Rep: metallophosphoesterase - Ignicoccus hospitalis KIN4/I Length = 384 Score = 37.1 bits (82), Expect = 0.53 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Frame = +3 Query: 105 ILIASDIHLGFMEND-PVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 I+ A+D+HLG + R ED + AFE+++ ++ D +++ GDLFD Sbjct: 3 IVHAADVHLGKRQYGLKEREEDFYKAFEDLVEATIREKADALVIAGDLFD 52 >UniRef50_O26641 Cluster: DNA double-strand break repair protein mre11; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: DNA double-strand break repair protein mre11 - Methanobacterium thermoautotrophicum Length = 587 Score = 37.1 bits (82), Expect = 0.53 Identities = 20/44 (45%), Positives = 27/44 (61%) Frame = +3 Query: 117 SDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 SD HLG ++ +R E F AF L A+Q DVD +++ GDLF Sbjct: 177 SDCHLGAQKHPDLR-ELEFEAFRMALDDALQKDVDFMIIAGDLF 219 >UniRef50_Q74D96 Cluster: Nuclease SbcCD, D subunit, putative; n=2; Geobacter|Rep: Nuclease SbcCD, D subunit, putative - Geobacter sulfurreducens Length = 376 Score = 36.7 bits (81), Expect = 0.70 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 5/60 (8%) Frame = +3 Query: 99 LRILIASDIHLG-----FMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNL 263 +R L +D+HL F + R D F+ +++LA++ +VD IL+ GDLFD ++ Sbjct: 3 IRFLHTADLHLDSPLRTFGDLARERRRDFLKTFDRIVNLAIKREVDCILIAGDLFDSTSV 62 >UniRef50_Q9YFY8 Cluster: DNA double-strand break repair protein mre11; n=1; Aeropyrum pernix|Rep: DNA double-strand break repair protein mre11 - Aeropyrum pernix Length = 409 Score = 36.7 bits (81), Expect = 0.70 Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Frame = +3 Query: 102 RILIASDIHLGFMEND-PVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNL 263 ++L +D+HLG R +D F +FE V+ A++ D +L+ GDLFD+ L Sbjct: 3 KVLHVADVHLGARPYGLEERRDDIFRSFEFVVETALKDRPDAVLIAGDLFDKPKL 57 >UniRef50_Q9AN75 Cluster: ID473; n=1; Bradyrhizobium japonicum|Rep: ID473 - Bradyrhizobium japonicum Length = 173 Score = 36.3 bits (80), Expect = 0.93 Identities = 18/54 (33%), Positives = 29/54 (53%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 +RIL +D H+G R + FE + + V+ DVD +++ GD+FD N Sbjct: 2 IRILHTADWHIGQTLRGFSREHEHRKVFERLEEIVVERDVDALIIAGDVFDSQN 55 >UniRef50_Q0HTQ0 Cluster: Nuclease SbcCD, D subunit precursor; n=40; Gammaproteobacteria|Rep: Nuclease SbcCD, D subunit precursor - Shewanella sp. (strain MR-7) Length = 400 Score = 36.3 bits (80), Expect = 0.93 Identities = 15/52 (28%), Positives = 31/52 (59%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 +R + SD H+G ++ ED +++++LA Q VD +++ GD++D+ Sbjct: 1 MRFIHTSDWHIGRQLHNQSLLEDQAYVLDQIVTLAEQHTVDAVIIAGDIYDR 52 >UniRef50_Q03B99 Cluster: DNA repair exonuclease; n=4; Lactobacillus|Rep: DNA repair exonuclease - Lactobacillus casei (strain ATCC 334) Length = 373 Score = 36.3 bits (80), Expect = 0.93 Identities = 19/52 (36%), Positives = 29/52 (55%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 +R L +D H+G ND ED FE+++ A VD I++ GDL+D+ Sbjct: 1 MRFLHTADWHIGKKLNDFDLLEDQQAVFEQLVETAETHKVDAIVIAGDLYDR 52 >UniRef50_Q7QVF9 Cluster: GLP_90_7352_9805; n=3; Giardia intestinalis|Rep: GLP_90_7352_9805 - Giardia lamblia ATCC 50803 Length = 817 Score = 36.3 bits (80), Expect = 0.93 Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Frame = +3 Query: 102 RILIASDIHLGFMEND--PVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNLLS 269 RI + +D HLGF P ++++ EE L LA + IL GD F+Q L S Sbjct: 9 RIALFTDTHLGFTAPSARPCNAHENYLLLEECLCLARKLGAHAILHAGDFFNQNRLSS 66 >UniRef50_Q2NFC6 Cluster: DNA double-strand break repair protein Mre11; n=1; Methanosphaera stadtmanae DSM 3091|Rep: DNA double-strand break repair protein Mre11 - Methanosphaera stadtmanae (strain DSM 3091) Length = 393 Score = 36.3 bits (80), Expect = 0.93 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Frame = +3 Query: 96 TLRILIASDIHLGFMENDPVRGEDSFI-AFEEVLSLAVQCDVDLILLGGDLFD 251 T++I +D HLG+ + E+ F FE+++ + DVD +L GDLF+ Sbjct: 2 TIKIAHMADTHLGYKQYGLNERENDFYKTFEKIIDDIISKDVDYVLHAGDLFE 54 >UniRef50_Q1FMZ5 Cluster: Nuclease SbcCD, D subunit; n=1; Clostridium phytofermentans ISDg|Rep: Nuclease SbcCD, D subunit - Clostridium phytofermentans ISDg Length = 375 Score = 35.9 bits (79), Expect = 1.2 Identities = 19/63 (30%), Positives = 37/63 (58%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLNLLSIVC 278 ++ + SD+H+G N+ ED +++L LA + D +L+ GD++D+ NL +I Sbjct: 1 MKFMHLSDLHIGKRVNEFSMIEDQTYILQKILELADEEKPDAVLIAGDVYDK-NLPTIEG 59 Query: 279 LNV 287 +N+ Sbjct: 60 VNL 62 >UniRef50_Q9HRW4 Cluster: DNA double-strand break repair protein mre11; n=5; Halobacteriaceae|Rep: DNA double-strand break repair protein mre11 - Halobacterium salinarium (Halobacterium halobium) Length = 387 Score = 35.9 bits (79), Expect = 1.2 Identities = 17/50 (34%), Positives = 30/50 (60%), Gaps = 1/50 (2%) Frame = +3 Query: 102 RILIASDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 R++ D HLG+ + + P R +D AF+ V++ A+ VD ++ GDL+ Sbjct: 3 RVIHTGDTHLGYQQYHAPQRRQDFLDAFDAVITDAIDEGVDAVVHAGDLY 52 >UniRef50_A6TVN1 Cluster: Nuclease SbcCD, D subunit; n=3; Clostridiaceae|Rep: Nuclease SbcCD, D subunit - Alkaliphilus metalliredigens QYMF Length = 406 Score = 35.5 bits (78), Expect = 1.6 Identities = 19/56 (33%), Positives = 35/56 (62%), Gaps = 2/56 (3%) Frame = +3 Query: 99 LRILIASDIHLG--FMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 ++IL SD HLG N + ++ F+ EE++++ + ++DLIL+ GD++D N Sbjct: 1 MKILHTSDWHLGKTLEGNSRLAEQERFL--EELVTIVNEKEIDLILVAGDIYDTSN 54 >UniRef50_Q8TXI3 Cluster: DNA double-strand break repair protein mre11; n=1; Methanopyrus kandleri|Rep: DNA double-strand break repair protein mre11 - Methanopyrus kandleri Length = 451 Score = 35.5 bits (78), Expect = 1.6 Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 1/52 (1%) Frame = +3 Query: 99 LRILIASDIHLGF-MENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 +R+ +D+HLG + N R E FE ++ +C VD++++ GDLF+ Sbjct: 1 MRMAHVADVHLGHALMNLRSREEAVMETFERLMEEVRECSVDVLVIAGDLFE 52 >UniRef50_Q5LYZ3 Cluster: ATP-dependent dsDNA exonuclease; n=6; Streptococcaceae|Rep: ATP-dependent dsDNA exonuclease - Streptococcus thermophilus (strain CNRZ 1066) Length = 408 Score = 35.1 bits (77), Expect = 2.1 Identities = 17/52 (32%), Positives = 31/52 (59%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 ++ L SD H+G N E+ AF++++ LA+ VD +++ GDL+D+ Sbjct: 7 MKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEKVDGVIISGDLYDR 58 >UniRef50_Q2AE44 Cluster: Metallophosphoesterase; n=1; Halothermothrix orenii H 168|Rep: Metallophosphoesterase - Halothermothrix orenii H 168 Length = 464 Score = 35.1 bits (77), Expect = 2.1 Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 9/63 (14%) Frame = +3 Query: 93 DTLRILIASDIHLGFMENDPVR-----GE----DSFIAFEEVLSLAVQCDVDLILLGGDL 245 D L+ + ASDIHLG + + GE ++ AF + + A++ +VD ++L GD+ Sbjct: 8 DELKFIHASDIHLGSVLHTGTTHKGDIGEIVKKATYKAFSRICNHAIEFEVDFVVLSGDI 67 Query: 246 FDQ 254 FD+ Sbjct: 68 FDR 70 >UniRef50_A5IU09 Cluster: Metallophosphoesterase; n=16; Staphylococcus|Rep: Metallophosphoesterase - Staphylococcus aureus subsp. aureus JH9 Length = 398 Score = 35.1 bits (77), Expect = 2.1 Identities = 12/33 (36%), Positives = 24/33 (72%) Frame = +3 Query: 162 EDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 + ++ +F+ ++ +A+Q DVD +++ GDLFD N Sbjct: 32 KSAYESFKNIVDIALQQDVDFVIIAGDLFDSEN 64 >UniRef50_A1S0I8 Cluster: Metallophosphoesterase; n=1; Thermofilum pendens Hrk 5|Rep: Metallophosphoesterase - Thermofilum pendens (strain Hrk 5) Length = 391 Score = 35.1 bits (77), Expect = 2.1 Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 5/61 (8%) Frame = +3 Query: 93 DTLRILIASDIHLG--FMENDPV---RGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQL 257 + LRI+ +D HL F P R ED AF V+ AV+ L L+ GDLFD + Sbjct: 2 EVLRIVHTADNHLDPKFTFLGPKVRDRREDFLNAFRRVVDFAVEAKPHLFLVSGDLFDSV 61 Query: 258 N 260 N Sbjct: 62 N 62 >UniRef50_P62132 Cluster: DNA double-strand break repair protein mre11; n=1; Nanoarchaeum equitans|Rep: DNA double-strand break repair protein mre11 - Nanoarchaeum equitans Length = 361 Score = 35.1 bits (77), Expect = 2.1 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Frame = +3 Query: 105 ILIASDIHLG-FMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 I SD+HLG N E S+ A ++ ++ DL+L+GGD+FD+ Sbjct: 2 IAFISDLHLGNIYANKKETEEHSYNALAKIEEKLLEYQPDLVLVGGDIFDK 52 >UniRef50_A4YET4 Cluster: Metallophosphoesterase; n=1; Metallosphaera sedula DSM 5348|Rep: Metallophosphoesterase - Metallosphaera sedula DSM 5348 Length = 379 Score = 34.7 bits (76), Expect = 2.8 Identities = 20/50 (40%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Frame = +3 Query: 105 ILIASDIHLGFME-NDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 IL SD HLG N R +D + F +++ LA++ V I+ GDLFD Sbjct: 2 ILHISDTHLGSRRYNRDSREQDVYDVFSQLIDLAIREHVRAIVHSGDLFD 51 >UniRef50_Q67MD2 Cluster: DNA repair exonuclease; n=1; Symbiobacterium thermophilum|Rep: DNA repair exonuclease - Symbiobacterium thermophilum Length = 411 Score = 34.3 bits (75), Expect = 3.7 Identities = 18/54 (33%), Positives = 30/54 (55%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 +RIL +D HLG R E+ +E+ ++ + +DL+L+ GD+FD N Sbjct: 1 MRILHTADWHLGRTLEGRSRQEEHEAFVDELCAMVREERIDLVLIAGDVFDTGN 54 >UniRef50_Q5SIS5 Cluster: Exonuclease SbcD; n=2; Thermus thermophilus|Rep: Exonuclease SbcD - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Length = 372 Score = 34.3 bits (75), Expect = 3.7 Identities = 18/52 (34%), Positives = 29/52 (55%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 +R+L +D HLG + R + A ++L L VDL+++ GDLFD+ Sbjct: 1 MRLLHTADWHLGKLLKGVDRTPEIAAALRDLLGLVRSERVDLVVVSGDLFDR 52 >UniRef50_Q22P75 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 430 Score = 34.3 bits (75), Expect = 3.7 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Frame = +2 Query: 281 KCTEIIR-KYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNHDDPVGQG 457 KC ++ + L + + +E L + K+ + N E NL+ISY S+H H +G Sbjct: 76 KCQNLVDLELILRNTEIKLENLKNIYKDLEKLTNIEKLNLDISYNTFSLHAEHKYMMGID 135 Query: 458 SVSSLDILSIT 490 ++L S++ Sbjct: 136 KCTNLVSFSLS 146 >UniRef50_Q6L2H7 Cluster: DNA repair protein; n=2; Thermoplasmatales|Rep: DNA repair protein - Picrophilus torridus Length = 370 Score = 34.3 bits (75), Expect = 3.7 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFI-AFEEVLSLAVQCDVDLILLGGDLFD 251 +R + SD HLG+ + E+ F AF E + + + VD + GDLFD Sbjct: 2 VRFIHFSDTHLGYKQYMMDERENDFYEAFNEAIDIGINEHVDFFVHSGDLFD 53 >UniRef50_Q38Y02 Cluster: Putative metallo-phosphoesterase; n=1; Lactobacillus sakei subsp. sakei 23K|Rep: Putative metallo-phosphoesterase - Lactobacillus sakei subsp. sakei (strain 23K) Length = 397 Score = 33.9 bits (74), Expect = 4.9 Identities = 15/31 (48%), Positives = 21/31 (67%) Frame = +3 Query: 162 EDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 E +F AFE+++ A+ VD +LL GD FDQ Sbjct: 31 ESTFTAFEKLVQTAIDEAVDFVLLVGDSFDQ 61 >UniRef50_Q2S5E8 Cluster: Outer membrane protein, putative; n=1; Salinibacter ruber DSM 13855|Rep: Outer membrane protein, putative - Salinibacter ruber (strain DSM 13855) Length = 943 Score = 33.9 bits (74), Expect = 4.9 Identities = 20/59 (33%), Positives = 32/59 (54%) Frame = -2 Query: 330 LTGLSPRQYLRIISVHLNIQLTEGLVDQTDHLLKVSNQHHIVPQETKLLQKL*SYLLRV 154 L GL+P +L + V N+ LT+ +D+T+ +L + Q P ET+ LQ Y+ V Sbjct: 789 LGGLAP--WLEHVQVGGNLTLTQSQIDRTEEVLTLIRQFRDDPDETRQLQGQSPYIANV 845 >UniRef50_Q2S4Q6 Cluster: Nuclease SbcCD, D subunit subfamily, putative; n=1; Salinibacter ruber DSM 13855|Rep: Nuclease SbcCD, D subunit subfamily, putative - Salinibacter ruber (strain DSM 13855) Length = 453 Score = 33.9 bits (74), Expect = 4.9 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Frame = +2 Query: 389 PNLNISYPILSIHGNHDDPVGQGSVSSLDILS-ITGLVNYF 508 P + P++ I GNHD PV G SSLDI I G V+ + Sbjct: 99 PLADADIPVVLIVGNHDHPVTFGRASSLDIFDHIAGAVHCY 139 >UniRef50_A7HL21 Cluster: Metallophosphoesterase; n=1; Fervidobacterium nodosum Rt17-B1|Rep: Metallophosphoesterase - Fervidobacterium nodosum Rt17-B1 Length = 397 Score = 33.9 bits (74), Expect = 4.9 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 8/59 (13%) Frame = +3 Query: 99 LRILIASDIHLG------FMEND--PVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 ++IL SD HLG EN R D F A E ++ A++ +VDL ++ GDLFD Sbjct: 1 MKILHTSDWHLGKRPVGGIGENSYSDFRYNDYFNAAEYIVDRAIEENVDLFIIAGDLFD 59 >UniRef50_A7HCA1 Cluster: Nuclease SbcCD, D subunit; n=1; Anaeromyxobacter sp. Fw109-5|Rep: Nuclease SbcCD, D subunit - Anaeromyxobacter sp. Fw109-5 Length = 386 Score = 33.9 bits (74), Expect = 4.9 Identities = 19/52 (36%), Positives = 28/52 (53%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 LRIL SD HLG ++ ED A E + + + D +L+ GD+FD+ Sbjct: 8 LRILHTSDWHLGRALHEESLLEDQAWALERLREVLREARPDALLIAGDVFDR 59 >UniRef50_A7BEB8 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 425 Score = 33.9 bits (74), Expect = 4.9 Identities = 19/62 (30%), Positives = 32/62 (51%) Frame = +3 Query: 69 DISAWSPDDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLF 248 D+ A + IL SD HLG + G+ + E +++L + VD +L+ GD+F Sbjct: 15 DVGALCHTGDMLILHTSDWHLGRTLHGASLGDSADAFIEWLVALVRERGVDAVLISGDVF 74 Query: 249 DQ 254 D+ Sbjct: 75 DR 76 >UniRef50_Q4XVJ3 Cluster: Putative uncharacterized protein; n=3; Plasmodium (Vinckeia)|Rep: Putative uncharacterized protein - Plasmodium chabaudi Length = 283 Score = 33.9 bits (74), Expect = 4.9 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = +2 Query: 293 IIRKYCLGDKPVSIELLSDQIKNFSRTVNYEDPNLNISYPILSIHGNHDDPV-GQGSVSS 469 II KY +K S E LS+++ NF ++ +NIS I + N + P+ G+V+S Sbjct: 158 IIDKYIDKNKAYSQEELSNELNNFFNNFYLQNFQINISQDIFKANDNENQPIHDDGTVTS 217 >UniRef50_Q88WS0 Cluster: Exonuclease SbcD; n=2; Lactobacillales|Rep: Exonuclease SbcD - Lactobacillus plantarum Length = 393 Score = 33.5 bits (73), Expect = 6.5 Identities = 15/52 (28%), Positives = 33/52 (63%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 +++L +D H+G N ++ AF+++L++A+ VD I++ GD++D+ Sbjct: 1 MKLLHTADWHIGRTLNGYSLLDEQEAAFKQILTIALAEKVDGIVIAGDIYDR 52 >UniRef50_Q74CF0 Cluster: Nuclease SbcCD, D subunit, putative; n=6; Bacteria|Rep: Nuclease SbcCD, D subunit, putative - Geobacter sulfurreducens Length = 418 Score = 33.5 bits (73), Expect = 6.5 Identities = 15/49 (30%), Positives = 27/49 (55%) Frame = +2 Query: 356 KNFSRTVNYEDPNLNISYPILSIHGNHDDPVGQGSVSSLDILSITGLVN 502 + F+RT+ P N P +++ GNHD + S+S ++ LS G ++ Sbjct: 65 RTFARTIETLQPLKNAGIPCIAVEGNHDWIHRRDSISWMEALSQMGYIH 113 >UniRef50_Q6I2G3 Cluster: DNA repair exonuclease family protein; n=11; Bacillus cereus group|Rep: DNA repair exonuclease family protein - Bacillus anthracis Length = 432 Score = 33.5 bits (73), Expect = 6.5 Identities = 13/30 (43%), Positives = 21/30 (70%) Frame = +3 Query: 162 EDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 + +F +FE ++ A+Q VD +LL GDL+D Sbjct: 54 QSTFESFERIIDKAIQERVDFVLLAGDLYD 83 >UniRef50_Q04FF3 Cluster: DNA repair exonuclease; n=2; Oenococcus oeni|Rep: DNA repair exonuclease - Oenococcus oeni (strain BAA-331 / PSU-1) Length = 413 Score = 33.5 bits (73), Expect = 6.5 Identities = 15/28 (53%), Positives = 18/28 (64%) Frame = +3 Query: 168 SFIAFEEVLSLAVQCDVDLILLGGDLFD 251 +F AF V+ LAV VD +L GDLFD Sbjct: 45 TFTAFSNVIKLAVDRHVDFVLFPGDLFD 72 >UniRef50_Q6CKL0 Cluster: Similarity; n=1; Kluyveromyces lactis|Rep: Similarity - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 369 Score = 33.5 bits (73), Expect = 6.5 Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Frame = +2 Query: 542 HQYFCKKVLRGSPSMGLSHLKDQRLSRLFAEK---KVEMERPDETLGLGSIYLYYIQIML 712 H + C K++ G+ +HL ++L+ L +K V + ++ + LG YL + M Sbjct: 83 HWFICTKIMSGNNLSSANHLDSEKLTELLRKKYPFLVMYDGKNDVIDLGKFYLGFAHFMS 142 Query: 713 TEDT 724 E T Sbjct: 143 REIT 146 >UniRef50_Q7UKG1 Cluster: Probable phosphoesterase yhaO-putative DNA repair exonuclease; n=1; Pirellula sp.|Rep: Probable phosphoesterase yhaO-putative DNA repair exonuclease - Rhodopirellula baltica Length = 431 Score = 33.1 bits (72), Expect = 8.6 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 9/59 (15%) Frame = +3 Query: 102 RILIASDIHLGF-------MENDPVRG--EDSFIAFEEVLSLAVQCDVDLILLGGDLFD 251 RIL A+DIHL E+ PV E S A E + LA++ VDL+++ GDL+D Sbjct: 5 RILHAADIHLDSPLQKLDAYEDAPVDEIREASRRALENMTDLAIEEQVDLVVIAGDLYD 63 >UniRef50_Q65LT8 Cluster: YhaO; n=4; Bacillus|Rep: YhaO - Bacillus licheniformis (strain DSM 13 / ATCC 14580) Length = 414 Score = 33.1 bits (72), Expect = 8.6 Identities = 15/31 (48%), Positives = 19/31 (61%) Frame = +3 Query: 168 SFIAFEEVLSLAVQCDVDLILLGGDLFDQLN 260 +F + E V LA+ D ILL GDLFD+ N Sbjct: 42 TFKSAENVFKLAIDEQADFILLAGDLFDEAN 72 >UniRef50_Q2RL80 Cluster: Metallophosphoesterase; n=1; Moorella thermoacetica ATCC 39073|Rep: Metallophosphoesterase - Moorella thermoacetica (strain ATCC 39073) Length = 374 Score = 33.1 bits (72), Expect = 8.6 Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 8/58 (13%) Frame = +3 Query: 102 RILIASDIHLGFMEN--DPVRGEDSFIAFEEVLSLAVQCDVD------LILLGGDLFD 251 R+L +D+HLG+ + PVR E+ + A VL AV +D L+L+ GDLFD Sbjct: 3 RVLHLADLHLGYRPDLPAPVR-EEVYRARNRVLQAAVDLALDPRQGISLVLIAGDLFD 59 >UniRef50_A6P235 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 380 Score = 33.1 bits (72), Expect = 8.6 Identities = 16/52 (30%), Positives = 29/52 (55%) Frame = +3 Query: 99 LRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQ 254 ++++ SD+HLG ND ED E+L + + D +L+ GD++D+ Sbjct: 1 MKLIHLSDLHLGKRVNDFSMLEDQQYILAEILQIIDREKPDGVLIAGDVYDK 52 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 829,428,748 Number of Sequences: 1657284 Number of extensions: 17191251 Number of successful extensions: 39428 Number of sequences better than 10.0: 99 Number of HSP's better than 10.0 without gapping: 37838 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 39313 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 70914189703 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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