Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV31051
(765 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ012737-1|CAB46442.1| 2692|Homo sapiens filamin, muscle isoform... 49 2e-05
AF252549-1|AAF67190.1| 2725|Homo sapiens gamma-filamin protein. 49 2e-05
AF184126-1|AAF68195.1| 2705|Homo sapiens filamin 2 protein. 49 2e-05
AF146692-1|AAF80245.1| 2691|Homo sapiens filamin 2 protein. 49 2e-05
AF089841-1|AAD12245.1| 2705|Homo sapiens gamma-filamin protein. 49 2e-05
X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for ... 47 6e-05
L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein. 47 6e-05
BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin... 47 6e-05
BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin... 47 6e-05
BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin... 47 6e-05
BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin... 47 6e-05
BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin... 47 6e-05
BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin... 47 6e-05
AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein. 47 6e-05
AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein. 47 6e-05
AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein. 47 6e-05
AB208865-1|BAD92102.1| 1342|Homo sapiens gamma filamin variant p... 46 2e-04
BX641085-1|CAE46040.1| 2422|Homo sapiens hypothetical protein pr... 45 3e-04
AF191633-1|AAF72339.1| 2602|Homo sapiens filamin protein. 45 3e-04
AF043045-1|AAC33845.1| 2602|Homo sapiens actin-binding protein h... 45 3e-04
AF042166-1|AAC39842.1| 2602|Homo sapiens beta-filamin protein. 45 3e-04
AB209889-1|BAD93126.1| 1613|Homo sapiens filamin B, beta (actin ... 45 3e-04
AB191258-1|BAD52434.1| 2591|Homo sapiens filamin B protein. 45 3e-04
AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein. 41 0.006
X70084-1|CAA49689.1| 431|Homo sapiens filamin protein. 40 0.013
BX664723-4|CAI43200.2| 281|Homo sapiens filamin A, alpha (actin... 36 0.16
BC109289-1|AAI09290.3| 307|Homo sapiens FLNA protein protein. 36 0.16
BC067111-1|AAH67111.1| 983|Homo sapiens FLNA protein protein. 36 0.16
BC014654-1|AAH14654.1| 838|Homo sapiens FLNA protein protein. 36 0.16
AL137574-1|CAB70818.1| 729|Homo sapiens hypothetical protein pr... 32 2.0
BX664723-5|CAI43201.1| 231|Homo sapiens filamin A, alpha (actin... 32 2.6
AF238609-1|AAF97046.1| 672|Homo sapiens filamen B protein. 32 2.6
Y09321-1|CAA70499.1| 801|Homo sapiens TBP associated factor pro... 31 3.4
AB234096-1|BAF51561.1| 867|Homo sapiens TATA box binding protei... 31 3.4
BC031054-1|AAH31054.2| 635|Homo sapiens OSGIN2 protein protein. 31 4.5
X85018-1|CAA59380.1| 559|Homo sapiens UDP-GalNAc:polypeptide N-... 30 7.9
U41514-1|AAC50327.1| 559|Homo sapiens UDP-GalNAc:polypeptide N-... 30 7.9
BC038440-1|AAH38440.1| 499|Homo sapiens GALNT1 protein protein. 30 7.9
>AJ012737-1|CAB46442.1| 2692|Homo sapiens filamin, muscle isoform
protein.
Length = 2692
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/73 (35%), Positives = 35/73 (47%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
PT P Y I I + A I GSP + S + SG GL VG+ A FT+ C+E
Sbjct: 1123 PTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSE 1182
Query: 721 DTSPTVEVERLSN 759
+ +E LS+
Sbjct: 1183 AGEAELTIEILSD 1195
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL-AHAHV 684
KDG V P P Y + IT+GG PI GSP + V KCSG GL A
Sbjct: 1401 KDGSC-TVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRA 1459
Query: 685 GKEAAFTIHCAE 720
FT+ C++
Sbjct: 1460 RVPQTFTVDCSQ 1471
Score = 44.0 bits (99), Expect = 6e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V P Q+V A G GL QV K A F ++ +G
Sbjct: 547 VTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGF 606
Query: 183 VVSGP 197
+ GP
Sbjct: 607 SIEGP 611
Score = 40.3 bits (90), Expect = 0.007
Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDVVV 188
++GAPI R P V V + ASG G +V +VA F + T G + E V V
Sbjct: 454 FAGAPITRSPFPVHVSEACNPNACRASGRGPQPKGVRVKEVADFKVFTKGAGSGELKVTV 513
Query: 189 SGPGSRALPVRCYQTKSGLLQ 251
GP PV+ + G+ +
Sbjct: 514 KGPKGTEEPVKVREAGDGVFE 534
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/67 (40%), Positives = 33/67 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR PT +++ I Y G I GSP+ V +S G GL+H V
Sbjct: 1785 KDG-TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPGLSHGMVN 1842
Query: 688 KEAAFTI 708
K A FTI
Sbjct: 1843 KPATFTI 1849
Score = 38.7 bits (86), Expect = 0.023
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Frame = +2
Query: 248 ASKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFS 418
A ++ E G +++ + PV GSP+ E DP++V G + TP FS
Sbjct: 1025 AVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFS 1084
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ TK A G L + E E +I
Sbjct: 1085 IDTKGADTGGLGLTVEGPCEAKI 1107
Score = 37.5 bits (83), Expect = 0.052
Identities = 20/56 (35%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P VP Y + IT+GG I SP + V + G GL VGK A F +
Sbjct: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVV 594
Score = 36.7 bits (81), Expect = 0.091
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISL-GVLSGRSSSAAKCSGTGLAHAHVGKEAAFT 705
VR P Y++ ITY G P+ GSP ++ GVL S G GL VG A F+
Sbjct: 1026 VRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVC-AYGPGLKGGLVGTPAPFS 1084
Query: 706 I 708
I
Sbjct: 1085 I 1085
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Frame = +2
Query: 320 GSPYTCESFDPNRVIVSGL---PTGNIVAQTPINFSVVTKDAGVGELDVVCE 466
G+P + +P + I G P GN V Q P +F+V T DAGVGE+ V E
Sbjct: 265 GAPVRSKQLNPKKAIAYGPGIEPQGNTVLQ-PAHFTVQTVDAGVGEVLVYIE 315
Score = 35.9 bits (79), Expect = 0.16
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVS--GLPTGNIVAQTPINFS 418
K+T G+ TI VL ++ + SP+ + S D ++V GL + P +F+
Sbjct: 832 KYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFT 891
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTH 523
V+TK AG +LDV + G + + D +D H
Sbjct: 892 VLTKGAGKAKLDV--QFAGTAKGEVVRDFEIIDNH 924
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTG 666
K T R RP + + +++ + GAPI SP + V + +A + SG G
Sbjct: 431 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRG 483
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+ + G P+ P V+ P +V A G GL V A FSIDT G + V
Sbjct: 1040 ITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGADTGGLGLTV 1099
Query: 189 SGP 197
GP
Sbjct: 1100 EGP 1102
Score = 34.7 bits (76), Expect = 0.37
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G VA P FS
Sbjct: 2244 RFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFS 2303
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2304 IWTREAGAGGLSIAVEGPSKAEI 2326
Score = 33.5 bits (73), Expect = 0.85
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Frame = +2
Query: 209 TARKMLS-NQVWLVASKFTINEVGQSTIEVLHLSKPVSGSP--YTCESFDPNRVIVSGLP 379
TAR ++ N+ + ++ E G + + + + GSP + ++ + V G
Sbjct: 1776 TARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPG 1835
Query: 380 TGNIVAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
+ + P F++VTKDAG G L + E + I
Sbjct: 1836 LSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEI 1871
Score = 32.3 bits (70), Expect = 2.0
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGN 388
+++ N + K+T + G + V + PV SP+ D +++ V GL +
Sbjct: 919 EIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKV 978
Query: 389 IVAQTPINFSVVTKDA-GVGELDVVCEAMGERRI 487
V Q FSV T+ A G G+LDV + R I
Sbjct: 979 AVGQEQA-FSVNTRGAGGQGQLDVRMTSPSRRPI 1011
Score = 30.7 bits (66), Expect = 6.0
Identities = 20/78 (25%), Positives = 30/78 (38%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+L+ + + P V V V A G GL VNK F+++T G + +
Sbjct: 1328 VLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAI 1387
Query: 189 SGPGSRALPVRCYQTKSG 242
GP + C K G
Sbjct: 1388 EGPSEAKM--SCKDNKDG 1403
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/57 (35%), Positives = 28/57 (49%)
Frame = +3
Query: 72 HGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSGPGSRALPVRCYQTKSG 242
+ + V+A G GL VNK A+F+I T + V GP S+A + C K G
Sbjct: 1825 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGP-SKA-EITCKDNKDG 1879
>AF252549-1|AAF67190.1| 2725|Homo sapiens gamma-filamin protein.
Length = 2725
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/73 (35%), Positives = 35/73 (47%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
PT P Y I I + A I GSP + S + SG GL VG+ A FT+ C+E
Sbjct: 1123 PTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSE 1182
Query: 721 DTSPTVEVERLSN 759
+ +E LS+
Sbjct: 1183 AGEAELTIEILSD 1195
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL-AHAHV 684
KDG V P P Y + IT+GG PI GSP + V KCSG GL A
Sbjct: 1401 KDGSC-TVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRA 1459
Query: 685 GKEAAFTIHCAE 720
FT+ C++
Sbjct: 1460 RVPQTFTVDCSQ 1471
Score = 44.0 bits (99), Expect = 6e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V P Q+V A G GL QV K A F ++ +G
Sbjct: 547 VTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGF 606
Query: 183 VVSGP 197
+ GP
Sbjct: 607 SIEGP 611
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDVVV 188
++GAPI R P V V + ASG GL +V +VA F + T G + E V V
Sbjct: 454 FAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTV 513
Query: 189 SGPGSRALPVRCYQTKSGLLQ 251
GP PV+ + G+ +
Sbjct: 514 KGPKGTEEPVKVREAGDGVFE 534
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Frame = +2
Query: 248 ASKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFS 418
A ++ E G +++ + PV GSP+ E DP++V G + TP FS
Sbjct: 1025 AVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFS 1084
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ TK AG G L + E E +I
Sbjct: 1085 IDTKGAGTGGLGLTVEGPCEAKI 1107
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/67 (40%), Positives = 33/67 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR PT +++ I Y G I GSP+ V +S G GL+H V
Sbjct: 1818 KDG-TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPGLSHGMVN 1875
Query: 688 KEAAFTI 708
K A FTI
Sbjct: 1876 KPATFTI 1882
Score = 37.5 bits (83), Expect = 0.052
Identities = 20/56 (35%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P VP Y + IT+GG I SP + V + G GL VGK A F +
Sbjct: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVV 594
Score = 37.1 bits (82), Expect = 0.069
Identities = 17/54 (31%), Positives = 27/54 (50%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
K T R RP + + +++ + GAPI SP + V + +A + SG GL
Sbjct: 431 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGL 484
Score = 36.7 bits (81), Expect = 0.091
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISL-GVLSGRSSSAAKCSGTGLAHAHVGKEAAFT 705
VR P Y++ ITY G P+ GSP ++ GVL S G GL VG A F+
Sbjct: 1026 VRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVC-AYGPGLKGGLVGTPAPFS 1084
Query: 706 I 708
I
Sbjct: 1085 I 1085
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Frame = +2
Query: 320 GSPYTCESFDPNRVIVSGL---PTGNIVAQTPINFSVVTKDAGVGELDVVCE 466
G+P + +P + I G P GN V Q P +F+V T DAGVGE+ V E
Sbjct: 265 GAPVRSKQLNPKKAIAYGPGIEPQGNTVLQ-PAHFTVQTVDAGVGEVLVYIE 315
Score = 35.9 bits (79), Expect = 0.16
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVS--GLPTGNIVAQTPINFS 418
K+T G+ TI VL ++ + SP+ + S D ++V GL + P +F+
Sbjct: 832 KYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFT 891
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTH 523
V+TK AG +LDV + G + + D +D H
Sbjct: 892 VLTKGAGKAKLDV--QFAGTAKGEVVRDFEIIDNH 924
Score = 34.7 bits (76), Expect = 0.37
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+ + G P+ P V+ P +V A G GL V A FSIDT G + V
Sbjct: 1040 ITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTV 1099
Query: 189 SGP 197
GP
Sbjct: 1100 EGP 1102
Score = 34.7 bits (76), Expect = 0.37
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G VA P FS
Sbjct: 2277 RFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFS 2336
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2337 IWTREAGAGGLSIAVEGPSKAEI 2359
Score = 33.5 bits (73), Expect = 0.85
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Frame = +2
Query: 209 TARKMLS-NQVWLVASKFTINEVGQSTIEVLHLSKPVSGSP--YTCESFDPNRVIVSGLP 379
TAR ++ N+ + ++ E G + + + + GSP + ++ + V G
Sbjct: 1809 TARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPG 1868
Query: 380 TGNIVAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
+ + P F++VTKDAG G L + E + I
Sbjct: 1869 LSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEI 1904
Score = 32.3 bits (70), Expect = 2.0
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGN 388
+++ N + K+T + G + V + PV SP+ D +++ V GL +
Sbjct: 919 EIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKV 978
Query: 389 IVAQTPINFSVVTKDA-GVGELDVVCEAMGERRI 487
V Q FSV T+ A G G+LDV + R I
Sbjct: 979 AVGQEQA-FSVNTRGAGGQGQLDVRMTSPSRRPI 1011
Score = 30.7 bits (66), Expect = 6.0
Identities = 20/78 (25%), Positives = 30/78 (38%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+L+ + + P V V V A G GL VNK F+++T G + +
Sbjct: 1328 VLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAI 1387
Query: 189 SGPGSRALPVRCYQTKSG 242
GP + C K G
Sbjct: 1388 EGPSEAKM--SCKDNKDG 1403
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/57 (35%), Positives = 28/57 (49%)
Frame = +3
Query: 72 HGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSGPGSRALPVRCYQTKSG 242
+ + V+A G GL VNK A+F+I T + V GP S+A + C K G
Sbjct: 1858 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGP-SKA-EITCKDNKDG 1912
>AF184126-1|AAF68195.1| 2705|Homo sapiens filamin 2 protein.
Length = 2705
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/73 (35%), Positives = 35/73 (47%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
PT P Y I I + A I GSP + S + SG GL VG+ A FT+ C+E
Sbjct: 1103 PTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSE 1162
Query: 721 DTSPTVEVERLSN 759
+ +E LS+
Sbjct: 1163 AGEAELTIEILSD 1175
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL-AHAHV 684
KDG V P P Y + IT+GG PI GSP + V KCSG GL A
Sbjct: 1381 KDGSC-TVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRA 1439
Query: 685 GKEAAFTIHCAE 720
FT+ C++
Sbjct: 1440 RVPQTFTVDCSQ 1451
Score = 44.0 bits (99), Expect = 6e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V P Q+V A G GL QV K A F ++ +G
Sbjct: 527 VTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGF 586
Query: 183 VVSGP 197
+ GP
Sbjct: 587 SIEGP 591
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDVVV 188
++GAPI R P V V + ASG GL +V +VA F + T G + E V V
Sbjct: 434 FAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTV 493
Query: 189 SGPGSRALPVRCYQTKSGLLQ 251
GP PV+ + G+ +
Sbjct: 494 KGPKGTEEPVKVREAGDGVFE 514
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Frame = +2
Query: 248 ASKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFS 418
A ++ E G +++ + PV GSP+ E DP++V G + TP FS
Sbjct: 1005 AVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFS 1064
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ TK AG G L + E E +I
Sbjct: 1065 IDTKGAGTGGLGLTVEGPCEAKI 1087
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/67 (40%), Positives = 33/67 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR PT +++ I Y G I GSP+ V +S G GL+H V
Sbjct: 1798 KDG-TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPGLSHGMVN 1855
Query: 688 KEAAFTI 708
K A FTI
Sbjct: 1856 KPATFTI 1862
Score = 37.5 bits (83), Expect = 0.052
Identities = 20/56 (35%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P VP Y + IT+GG I SP + V + G GL VGK A F +
Sbjct: 519 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVV 574
Score = 37.1 bits (82), Expect = 0.069
Identities = 17/54 (31%), Positives = 27/54 (50%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
K T R RP + + +++ + GAPI SP + V + +A + SG GL
Sbjct: 411 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGL 464
Score = 36.7 bits (81), Expect = 0.091
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISL-GVLSGRSSSAAKCSGTGLAHAHVGKEAAFT 705
VR P Y++ ITY G P+ GSP ++ GVL S G GL VG A F+
Sbjct: 1006 VRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVC-AYGPGLKGGLVGTPAPFS 1064
Query: 706 I 708
I
Sbjct: 1065 I 1065
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Frame = +2
Query: 320 GSPYTCESFDPNRVIVSGL---PTGNIVAQTPINFSVVTKDAGVGELDVVCE 466
G+P + +P + I G P GN V Q P +F+V T DAGVGE+ V E
Sbjct: 245 GAPVRSKQLNPKKAIAYGPGIEPQGNTVLQ-PAHFTVQTVDAGVGEVLVYIE 295
Score = 35.9 bits (79), Expect = 0.16
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVS--GLPTGNIVAQTPINFS 418
K+T G+ TI VL ++ + SP+ + S D ++V GL + P +F+
Sbjct: 812 KYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFT 871
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTH 523
V+TK AG +LDV + G + + D +D H
Sbjct: 872 VLTKGAGKAKLDV--QFAGTAKGEVVRDFEIIDNH 904
Score = 34.7 bits (76), Expect = 0.37
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+ + G P+ P V+ P +V A G GL V A FSIDT G + V
Sbjct: 1020 ITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTV 1079
Query: 189 SGP 197
GP
Sbjct: 1080 EGP 1082
Score = 33.5 bits (73), Expect = 0.85
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Frame = +2
Query: 209 TARKMLS-NQVWLVASKFTINEVGQSTIEVLHLSKPVSGSP--YTCESFDPNRVIVSGLP 379
TAR ++ N+ + ++ E G + + + + GSP + ++ + V G
Sbjct: 1789 TARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPG 1848
Query: 380 TGNIVAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
+ + P F++VTKDAG G L + E + I
Sbjct: 1849 LSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEI 1884
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 7/85 (8%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY--TCESFDPN-----RVIVSGLPTGNIVAQTPIN 412
+F E+G T+ V + + V GSP+ T R +GL G VA P
Sbjct: 2257 RFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGRAGLERG--VAGVPAE 2314
Query: 413 FSVVTKDAGVGELDVVCEAMGERRI 487
FS+ T++AG G L + E + I
Sbjct: 2315 FSIWTREAGAGGLSIAVEGPSKAEI 2339
Score = 32.3 bits (70), Expect = 2.0
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGN 388
+++ N + K+T + G + V + PV SP+ D +++ V GL +
Sbjct: 899 EIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKV 958
Query: 389 IVAQTPINFSVVTKDA-GVGELDVVCEAMGERRI 487
V Q FSV T+ A G G+LDV + R I
Sbjct: 959 AVGQEQA-FSVNTRGAGGQGQLDVRMTSPSRRPI 991
Score = 30.7 bits (66), Expect = 6.0
Identities = 20/78 (25%), Positives = 30/78 (38%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+L+ + + P V V V A G GL VNK F+++T G + +
Sbjct: 1308 VLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAI 1367
Query: 189 SGPGSRALPVRCYQTKSG 242
GP + C K G
Sbjct: 1368 EGPSEAKM--SCKDNKDG 1383
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/57 (35%), Positives = 28/57 (49%)
Frame = +3
Query: 72 HGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSGPGSRALPVRCYQTKSG 242
+ + V+A G GL VNK A+F+I T + V GP S+A + C K G
Sbjct: 1838 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGP-SKA-EITCKDNKDG 1892
>AF146692-1|AAF80245.1| 2691|Homo sapiens filamin 2 protein.
Length = 2691
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/73 (35%), Positives = 35/73 (47%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
PT P Y I I + A I GSP + S + SG GL VG+ A FT+ C+E
Sbjct: 1123 PTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSE 1182
Query: 721 DTSPTVEVERLSN 759
+ +E LS+
Sbjct: 1183 AGEAELTIEILSD 1195
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL-AHAHV 684
KDG V P P Y + IT+GG PI GSP + V KCSG GL A
Sbjct: 1401 KDGSC-TVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRA 1459
Query: 685 GKEAAFTIHCAE 720
FT+ C++
Sbjct: 1460 RVPQTFTVDCSQ 1471
Score = 44.0 bits (99), Expect = 6e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V P Q+V A G GL QV K A F ++ +G
Sbjct: 547 VTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGF 606
Query: 183 VVSGP 197
+ GP
Sbjct: 607 SIEGP 611
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDVVV 188
++GAPI R P V V + ASG GL +V +VA F + T G + E V V
Sbjct: 454 FAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTV 513
Query: 189 SGPGSRALPVRCYQTKSGLLQ 251
GP PV+ + G+ +
Sbjct: 514 KGPKGTEEPVKVREAGDGVFE 534
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Frame = +2
Query: 248 ASKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFS 418
A ++ E G +++ + PV GSP+ E DP++V G + TP FS
Sbjct: 1025 AVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFS 1084
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ TK AG G L + E E +I
Sbjct: 1085 IDTKGAGTGGLGLTVEGPCEAKI 1107
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/67 (40%), Positives = 33/67 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR PT +++ I Y G I GSP+ V +S G GL+H V
Sbjct: 1785 KDG-TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPGLSHGMVN 1842
Query: 688 KEAAFTI 708
K A FTI
Sbjct: 1843 KPATFTI 1849
Score = 37.5 bits (83), Expect = 0.052
Identities = 20/56 (35%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P VP Y + IT+GG I SP + V + G GL VGK A F +
Sbjct: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVV 594
Score = 37.1 bits (82), Expect = 0.069
Identities = 17/54 (31%), Positives = 27/54 (50%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
K T R RP + + +++ + GAPI SP + V + +A + SG GL
Sbjct: 431 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGL 484
Score = 36.7 bits (81), Expect = 0.091
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISL-GVLSGRSSSAAKCSGTGLAHAHVGKEAAFT 705
VR P Y++ ITY G P+ GSP ++ GVL S G GL VG A F+
Sbjct: 1026 VRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVC-AYGPGLKGGLVGTPAPFS 1084
Query: 706 I 708
I
Sbjct: 1085 I 1085
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Frame = +2
Query: 320 GSPYTCESFDPNRVIVSGL---PTGNIVAQTPINFSVVTKDAGVGELDVVCE 466
G+P + +P + I G P GN V Q P +F+V T DAGVGE+ V E
Sbjct: 265 GAPVRSKQLNPKKAIAYGPGIEPQGNTVLQ-PAHFTVQTVDAGVGEVLVYIE 315
Score = 35.9 bits (79), Expect = 0.16
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVS--GLPTGNIVAQTPINFS 418
K+T G+ TI VL ++ + SP+ + S D ++V GL + P +F+
Sbjct: 832 KYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFT 891
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTH 523
V+TK AG +LDV + G + + D +D H
Sbjct: 892 VLTKGAGKAKLDV--QFAGTAKGEVVRDFEIIDNH 924
Score = 34.7 bits (76), Expect = 0.37
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+ + G P+ P V+ P +V A G GL V A FSIDT G + V
Sbjct: 1040 ITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTV 1099
Query: 189 SGP 197
GP
Sbjct: 1100 EGP 1102
Score = 34.7 bits (76), Expect = 0.37
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G VA P FS
Sbjct: 2244 RFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFS 2303
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2304 IWTREAGAGGLSIAVEGPNKAEI 2326
Score = 33.5 bits (73), Expect = 0.85
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Frame = +2
Query: 209 TARKMLS-NQVWLVASKFTINEVGQSTIEVLHLSKPVSGSP--YTCESFDPNRVIVSGLP 379
TAR ++ N+ + ++ E G + + + + GSP + ++ + V G
Sbjct: 1776 TARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPG 1835
Query: 380 TGNIVAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
+ + P F++VTKDAG G L + E + I
Sbjct: 1836 LSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEI 1871
Score = 32.3 bits (70), Expect = 2.0
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGN 388
+++ N + K+T + G + V + PV SP+ D +++ V GL +
Sbjct: 919 EIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKV 978
Query: 389 IVAQTPINFSVVTKDA-GVGELDVVCEAMGERRI 487
V Q FSV T+ A G G+LDV + R I
Sbjct: 979 AVGQEQA-FSVNTRGAGGQGQLDVRMTSPSRRPI 1011
Score = 30.7 bits (66), Expect = 6.0
Identities = 20/78 (25%), Positives = 30/78 (38%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+L+ + + P V V V A G GL VNK F+++T G + +
Sbjct: 1328 VLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAI 1387
Query: 189 SGPGSRALPVRCYQTKSG 242
GP + C K G
Sbjct: 1388 EGPSEAKM--SCKDNKDG 1403
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/57 (35%), Positives = 28/57 (49%)
Frame = +3
Query: 72 HGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSGPGSRALPVRCYQTKSG 242
+ + V+A G GL VNK A+F+I T + V GP S+A + C K G
Sbjct: 1825 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGP-SKA-EITCKDNKDG 1879
>AF089841-1|AAD12245.1| 2705|Homo sapiens gamma-filamin protein.
Length = 2705
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/73 (35%), Positives = 35/73 (47%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
PT P Y I I + A I GSP + S + SG GL VG+ A FT+ C+E
Sbjct: 1103 PTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSE 1162
Query: 721 DTSPTVEVERLSN 759
+ +E LS+
Sbjct: 1163 AGEAELTIEILSD 1175
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL-AHAHV 684
KDG V P P Y + IT+GG PI GSP + V KCSG GL A
Sbjct: 1381 KDGSC-TVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRA 1439
Query: 685 GKEAAFTIHCAE 720
FT+ C++
Sbjct: 1440 RVPQTFTVDCSQ 1451
Score = 44.0 bits (99), Expect = 6e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V P Q+V A G GL QV K A F ++ +G
Sbjct: 527 VTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGF 586
Query: 183 VVSGP 197
+ GP
Sbjct: 587 SIEGP 591
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDVVV 188
++GAPI R P V V + ASG GL +V +VA F + T G + E V V
Sbjct: 434 FAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTV 493
Query: 189 SGPGSRALPVRCYQTKSGLLQ 251
GP PV+ + G+ +
Sbjct: 494 KGPKGTEEPVKVREAGDGVFE 514
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Frame = +2
Query: 248 ASKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFS 418
A ++ E G +++ + PV GSP+ E DP++V G + TP FS
Sbjct: 1005 AVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFS 1064
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ TK AG G L + E E +I
Sbjct: 1065 IDTKGAGTGGLGLTVEGPCEAKI 1087
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/67 (40%), Positives = 33/67 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR PT +++ I Y G I GSP+ V +S G GL+H V
Sbjct: 1798 KDG-TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPGLSHGMVN 1855
Query: 688 KEAAFTI 708
K A FTI
Sbjct: 1856 KPATFTI 1862
Score = 37.5 bits (83), Expect = 0.052
Identities = 20/56 (35%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P VP Y + IT+GG I SP + V + G GL VGK A F +
Sbjct: 519 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVV 574
Score = 37.1 bits (82), Expect = 0.069
Identities = 17/54 (31%), Positives = 27/54 (50%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
K T R RP + + +++ + GAPI SP + V + +A + SG GL
Sbjct: 411 KGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGL 464
Score = 36.7 bits (81), Expect = 0.091
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISL-GVLSGRSSSAAKCSGTGLAHAHVGKEAAFT 705
VR P Y++ ITY G P+ GSP ++ GVL S G GL VG A F+
Sbjct: 1006 VRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVC-AYGPGLKGGLVGTPAPFS 1064
Query: 706 I 708
I
Sbjct: 1065 I 1065
Score = 36.3 bits (80), Expect = 0.12
Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Frame = +2
Query: 320 GSPYTCESFDPNRVIVSGL---PTGNIVAQTPINFSVVTKDAGVGELDVVCE 466
G+P + +P + I G P GN V Q P +F+V T DAGVGE+ V E
Sbjct: 245 GAPVRSKQLNPKKAIAYGPGIEPQGNTVLQ-PAHFTVQTVDAGVGEVLVYIE 295
Score = 35.9 bits (79), Expect = 0.16
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVS--GLPTGNIVAQTPINFS 418
K+T G+ TI VL ++ + SP+ + S D ++V GL + P +F+
Sbjct: 812 KYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFT 871
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTH 523
V+TK AG +LDV + G + + D +D H
Sbjct: 872 VLTKGAGKAKLDV--QFAGTAKGEVVRDFEIIDNH 904
Score = 34.7 bits (76), Expect = 0.37
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+ + G P+ P V+ P +V A G GL V A FSIDT G + V
Sbjct: 1020 ITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTV 1079
Query: 189 SGP 197
GP
Sbjct: 1080 EGP 1082
Score = 33.5 bits (73), Expect = 0.85
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Frame = +2
Query: 209 TARKMLS-NQVWLVASKFTINEVGQSTIEVLHLSKPVSGSP--YTCESFDPNRVIVSGLP 379
TAR ++ N+ + ++ E G + + + + GSP + ++ + V G
Sbjct: 1789 TARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPG 1848
Query: 380 TGNIVAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
+ + P F++VTKDAG G L + E + I
Sbjct: 1849 LSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEI 1884
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 7/85 (8%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY--TCESFDPN-----RVIVSGLPTGNIVAQTPIN 412
+F E+G T+ V + + V GSP+ T R +GL G VA P
Sbjct: 2257 RFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGRAGLERG--VAGVPAE 2314
Query: 413 FSVVTKDAGVGELDVVCEAMGERRI 487
FS+ T++AG G L + E + I
Sbjct: 2315 FSIWTREAGAGGLSIAVEGPSKAEI 2339
Score = 32.3 bits (70), Expect = 2.0
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGN 388
+++ N + K+T + G + V + PV SP+ D +++ V GL +
Sbjct: 899 EIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKV 958
Query: 389 IVAQTPINFSVVTKDA-GVGELDVVCEAMGERRI 487
V Q FSV T+ A G G+LDV + R I
Sbjct: 959 AVGQEQA-FSVNTRGAGGQGQLDVRMTSPSRRPI 991
Score = 30.7 bits (66), Expect = 6.0
Identities = 20/78 (25%), Positives = 30/78 (38%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVV 188
+L+ + + P V V V A G GL VNK F+++T G + +
Sbjct: 1308 VLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAI 1367
Query: 189 SGPGSRALPVRCYQTKSG 242
GP + C K G
Sbjct: 1368 EGPSEAKM--SCKDNKDG 1383
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/57 (35%), Positives = 28/57 (49%)
Frame = +3
Query: 72 HGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSGPGSRALPVRCYQTKSG 242
+ + V+A G GL VNK A+F+I T + V GP S+A + C K G
Sbjct: 1838 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGP-SKA-EITCKDNKDG 1892
>X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for
actin-binding protein (filamin) (ABP-280). ).
Length = 2647
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1119 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1177
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1178 VGQFQVDCSSAGSAELTIE 1196
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1031 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1090
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1320 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1379
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1380 TRGAGTGGLGLAVEGPSEAKM 1400
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1214 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1272
Query: 691 EA 696
EA
Sbjct: 1273 EA 1274
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1406 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1459
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 552 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 611
Query: 183 VVSGP 197
V GP
Sbjct: 612 SVEGP 616
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1032 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1091
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1092 TKGAGTGGLGLTVEGPCEAQL 1112
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 721 DTSPTV 738
D T+
Sbjct: 604 DDVGTL 609
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2194 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2253
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2254 GVPAEFSIWTRE 2265
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 441 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 490
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 703 TI 708
T+
Sbjct: 1377 TV 1378
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1424 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1483
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1484 QVKVQGPKGLVEPVDVVDNADGTQTVN 1510
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
Query: 195 P 197
P
Sbjct: 1107 P 1107
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1824 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1881
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1882 KPATFTVN 1889
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2201 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2260
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2261 IWTREAGAGGLAIAVEGPSKAEI 2283
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 837 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 896
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 897 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 939
>L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein.
Length = 2647
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1119 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1177
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1178 VGQFQVDCSSAGSAELTIE 1196
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1031 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1090
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1320 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1379
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1380 TRGAGTGGLGLAVEGPSEAKM 1400
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1214 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1272
Query: 691 EA 696
EA
Sbjct: 1273 EA 1274
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1406 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1459
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 552 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 611
Query: 183 VVSGP 197
V GP
Sbjct: 612 SVEGP 616
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1032 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1091
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1092 TKGAGTGGLGLTVEGPCEAQL 1112
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 721 DTSPTV 738
D T+
Sbjct: 604 DDVGTL 609
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2194 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2253
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2254 GVPAEFSIWTRE 2265
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 441 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 490
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 703 TI 708
T+
Sbjct: 1377 TV 1378
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1424 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1483
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1484 QVKVQGPKGLVEPVDVVDNADGTQTVN 1510
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
Query: 195 P 197
P
Sbjct: 1107 P 1107
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1824 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1881
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1882 KPATFTVN 1889
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2201 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2260
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2261 IWTREAGAGGLAIAVEGPSKAEI 2283
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 837 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 896
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 897 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 939
>BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2647
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1119 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1177
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1178 VGQFQVDCSSAGSAELTIE 1196
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1031 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1090
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1320 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1379
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1380 TRGAGTGGLGLAVEGPSEAKM 1400
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1214 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1272
Query: 691 EA 696
EA
Sbjct: 1273 EA 1274
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1406 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1459
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 552 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 611
Query: 183 VVSGP 197
V GP
Sbjct: 612 SVEGP 616
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1032 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1091
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1092 TKGAGTGGLGLTVEGPCEAQL 1112
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 721 DTSPTV 738
D T+
Sbjct: 604 DDVGTL 609
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2194 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2253
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2254 GVPAEFSIWTRE 2265
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 441 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 490
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 703 TI 708
T+
Sbjct: 1377 TV 1378
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1424 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1483
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1484 QVKVQGPKGLVEPVDVVDNADGTQTVN 1510
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
Query: 195 P 197
P
Sbjct: 1107 P 1107
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1824 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1881
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1882 KPATFTVN 1889
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2201 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2260
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2261 IWTREAGAGGLAIAVEGPSKAEI 2283
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 837 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 896
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 897 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 939
>BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2639
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1119 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1177
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1178 VGQFQVDCSSAGSAELTIE 1196
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1031 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1090
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1320 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1379
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1380 TRGAGTGGLGLAVEGPSEAKM 1400
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1214 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1272
Query: 691 EA 696
EA
Sbjct: 1273 EA 1274
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1406 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1459
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 552 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 611
Query: 183 VVSGP 197
V GP
Sbjct: 612 SVEGP 616
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1032 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1091
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1092 TKGAGTGGLGLTVEGPCEAQL 1112
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 721 DTSPTV 738
D T+
Sbjct: 604 DDVGTL 609
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2186 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2245
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2246 GVPAEFSIWTRE 2257
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 441 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 490
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Frame = +1
Query: 502 HPKDGH--THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH 675
H +D H T+ V P V Y I I YGG I SP + + +S +G G+
Sbjct: 1595 HIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGP 1654
Query: 676 A-HVGKEAAFTI 708
+G+E T+
Sbjct: 1655 TIQIGEETVITV 1666
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 703 TI 708
T+
Sbjct: 1377 TV 1378
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1424 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1483
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1484 QVKVQGPKGLVEPVDVVDNADGTQTVN 1510
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
Query: 195 P 197
P
Sbjct: 1107 P 1107
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1816 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1873
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1874 KPATFTVN 1881
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2193 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2252
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2253 IWTREAGAGGLAIAVEGPSKAEI 2275
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 837 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 896
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 897 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 939
>BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2607
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1119 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1177
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1178 VGQFQVDCSSAGSAELTIE 1196
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1031 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1090
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1320 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1379
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1380 TRGAGTGGLGLAVEGPSEAKM 1400
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1214 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1272
Query: 691 EA 696
EA
Sbjct: 1273 EA 1274
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1406 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1459
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 552 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 611
Query: 183 VVSGP 197
V GP
Sbjct: 612 SVEGP 616
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1032 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1091
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1092 TKGAGTGGLGLTVEGPCEAQL 1112
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 721 DTSPTV 738
D T+
Sbjct: 604 DDVGTL 609
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2154 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2213
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2214 GVPAEFSIWTRE 2225
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 441 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 490
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Frame = +1
Query: 502 HPKDGH--THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH 675
H +D H T+ V P V Y I I YGG I SP + + +S +G G+
Sbjct: 1595 HIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGP 1654
Query: 676 A-HVGKEAAFTI 708
+G+E T+
Sbjct: 1655 TIQIGEETVITV 1666
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 703 TI 708
T+
Sbjct: 1377 TV 1378
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1424 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1483
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1484 QVKVQGPKGLVEPVDVVDNADGTQTVN 1510
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
Query: 195 P 197
P
Sbjct: 1107 P 1107
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1784 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1841
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1842 KPATFTVN 1849
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2161 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2220
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2221 IWTREAGAGGLAIAVEGPSKAEI 2243
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 837 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 896
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 897 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 939
>BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2647
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1119 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1177
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1178 VGQFQVDCSSAGSAELTIE 1196
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1031 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1090
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1320 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1379
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1380 TRGAGTGGLGLAVEGPSEAKM 1400
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1214 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1272
Query: 691 EA 696
EA
Sbjct: 1273 EA 1274
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1406 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1459
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 552 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 611
Query: 183 VVSGP 197
V GP
Sbjct: 612 SVEGP 616
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1032 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1091
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1092 TKGAGTGGLGLTVEGPCEAQL 1112
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 721 DTSPTV 738
D T+
Sbjct: 604 DDVGTL 609
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2194 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2253
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2254 GVPAEFSIWTRE 2265
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 441 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 490
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 703 TI 708
T+
Sbjct: 1377 TV 1378
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1424 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1483
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1484 QVKVQGPKGLVEPVDVVDNADGTQTVN 1510
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
Query: 195 P 197
P
Sbjct: 1107 P 1107
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1824 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1881
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1882 KPATFTVN 1889
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2201 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2260
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2261 IWTREAGAGGLAIAVEGPSKAEI 2283
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 837 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 896
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 897 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 939
>BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2639
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1119 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1177
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1178 VGQFQVDCSSAGSAELTIE 1196
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1031 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1090
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1320 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1379
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1380 TRGAGTGGLGLAVEGPSEAKM 1400
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1214 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1272
Query: 691 EA 696
EA
Sbjct: 1273 EA 1274
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1406 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1459
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 552 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 611
Query: 183 VVSGP 197
V GP
Sbjct: 612 SVEGP 616
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1032 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1091
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1092 TKGAGTGGLGLTVEGPCEAQL 1112
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 721 DTSPTV 738
D T+
Sbjct: 604 DDVGTL 609
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2186 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2245
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2246 GVPAEFSIWTRE 2257
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 441 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 490
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Frame = +1
Query: 502 HPKDGH--THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH 675
H +D H T+ V P V Y I I YGG I SP + + +S +G G+
Sbjct: 1595 HIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGP 1654
Query: 676 A-HVGKEAAFTI 708
+G+E T+
Sbjct: 1655 TIQIGEETVITV 1666
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 703 TI 708
T+
Sbjct: 1377 TV 1378
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1424 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1483
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1484 QVKVQGPKGLVEPVDVVDNADGTQTVN 1510
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
Query: 195 P 197
P
Sbjct: 1107 P 1107
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1816 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1873
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1874 KPATFTVN 1881
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2193 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2252
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2253 IWTREAGAGGLAIAVEGPSKAEI 2275
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 837 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 896
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 897 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 939
>BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2607
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1119 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1177
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1178 VGQFQVDCSSAGSAELTIE 1196
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1031 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1090
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1320 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1379
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1380 TRGAGTGGLGLAVEGPSEAKM 1400
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1214 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1272
Query: 691 EA 696
EA
Sbjct: 1273 EA 1274
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1406 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1459
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 552 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 611
Query: 183 VVSGP 197
V GP
Sbjct: 612 SVEGP 616
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1032 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1091
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1092 TKGAGTGGLGLTVEGPCEAQL 1112
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 721 DTSPTV 738
D T+
Sbjct: 604 DDVGTL 609
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2154 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2213
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2214 GVPAEFSIWTRE 2225
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 441 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 490
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Frame = +1
Query: 502 HPKDGH--THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH 675
H +D H T+ V P V Y I I YGG I SP + + +S +G G+
Sbjct: 1595 HIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGP 1654
Query: 676 A-HVGKEAAFTI 708
+G+E T+
Sbjct: 1655 TIQIGEETVITV 1666
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1317 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1376
Query: 703 TI 708
T+
Sbjct: 1377 TV 1378
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1424 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1483
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1484 QVKVQGPKGLVEPVDVVDNADGTQTVN 1510
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1047 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1106
Query: 195 P 197
P
Sbjct: 1107 P 1107
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1784 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1841
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1842 KPATFTVN 1849
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2161 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2220
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2221 IWTREAGAGGLAIAVEGPSKAEI 2243
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 837 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 896
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 897 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 939
>AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein.
Length = 2651
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1131 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1189
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1190 VGQFQVDCSSAGSAELTIE 1208
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1043 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1102
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1332 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1391
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1392 TRGAGTGGLGLAVEGPSEAKM 1412
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1226 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1284
Query: 691 EA 696
EA
Sbjct: 1285 EA 1286
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1418 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1471
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 564 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 623
Query: 183 VVSGP 197
V GP
Sbjct: 624 SVEGP 628
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1044 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1103
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1104 TKGAGTGGLGLTVEGPCEAQL 1124
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 556 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 615
Query: 721 DTSPTV 738
D T+
Sbjct: 616 DDVGTL 621
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2198 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2257
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2258 GVPAEFSIWTRE 2269
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 453 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 502
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Frame = +1
Query: 502 HPKDGH--THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH 675
H +D H T+ V P V Y I I YGG I SP + + +S +G G+
Sbjct: 1607 HIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGP 1666
Query: 676 A-HVGKEAAFTI 708
+G+E T+
Sbjct: 1667 TIQIGEETVITV 1678
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1329 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1388
Query: 703 TI 708
T+
Sbjct: 1389 TV 1390
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1436 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1495
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1496 QVKVQGPKGLVEPVDVVDNADGTQTVN 1522
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1059 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1118
Query: 195 P 197
P
Sbjct: 1119 P 1119
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1828 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1885
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1886 KPATFTVN 1893
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2205 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2264
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2265 IWTREAGAGGLAIAVEGPSKAEI 2287
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 849 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 908
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 909 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 951
>AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein.
Length = 2620
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1092 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1150
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1151 VGQFQVDCSSAGSAELTIE 1169
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1004 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1063
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1293 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1352
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1353 TRGAGTGGLGLAVEGPSEAKM 1373
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1187 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1245
Query: 691 EA 696
EA
Sbjct: 1246 EA 1247
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1379 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1432
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 525 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 584
Query: 183 VVSGP 197
V GP
Sbjct: 585 SVEGP 589
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1005 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1064
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1065 TKGAGTGGLGLTVEGPCEAQL 1085
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 517 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 576
Query: 721 DTSPTV 738
D T+
Sbjct: 577 DDVGTL 582
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2167 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2226
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2227 GVPAEFSIWTRE 2238
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 414 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 463
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1290 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1349
Query: 703 TI 708
T+
Sbjct: 1350 TV 1351
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1397 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1456
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1457 QVKVQGPKGLVEPVDVVDNADGTQTVN 1483
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1020 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1079
Query: 195 P 197
P
Sbjct: 1080 P 1080
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1797 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1854
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1855 KPATFTVN 1862
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2174 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2233
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2234 IWTREAGAGGLAIAVEGPSKAEI 2256
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 810 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 869
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 870 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 912
>AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein.
Length = 2612
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/79 (35%), Positives = 36/79 (45%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y I I + I GSP V+ +S KCSG GL A G+
Sbjct: 1092 DG-TCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGE 1150
Query: 691 EAAFTIHCAEDTSPTVEVE 747
F + C+ S + +E
Sbjct: 1151 VGQFQVDCSSAGSAELTIE 1169
Score = 44.0 bits (99), Expect = 6e-04
Identities = 22/60 (36%), Positives = 27/60 (45%)
Frame = +1
Query: 529 VRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
VR P Y + +TY G P+ GSP L ++ S K G GL G A FTI
Sbjct: 1004 VRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTI 1063
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 1293 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 1352
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 1353 TRGAGTGGLGLAVEGPSEAKM 1373
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 1187 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 1245
Query: 691 EA 696
EA
Sbjct: 1246 EA 1247
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 1379 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 1432
Score = 37.5 bits (83), Expect = 0.052
Identities = 22/65 (33%), Positives = 28/65 (43%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+T+ W G I R P V V Q+V A G GL V K A F ++ +G
Sbjct: 525 VTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGF 584
Query: 183 VVSGP 197
V GP
Sbjct: 585 SVEGP 589
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSVV 424
+F E G +EV + PV GSP+ E+ P++V G A +P F++
Sbjct: 1005 RFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTID 1064
Query: 425 TKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E ++
Sbjct: 1065 TKGAGTGGLGLTVEGPCEAQL 1085
Score = 37.1 bits (82), Expect = 0.069
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTIHCAE 720
P VP Y + IT+GG I SP + V + + + G GL VGK A F +
Sbjct: 517 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 576
Query: 721 DTSPTV 738
D T+
Sbjct: 577 DDVGTL 582
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 2159 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 2218
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 2219 GVPAEFSIWTRE 2230
Score = 35.5 bits (78), Expect = 0.21
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = +1
Query: 520 THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
T+R +PT+ + +++T+ G PI SP ++ V + SA + G GL
Sbjct: 414 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGL 463
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Frame = +1
Query: 502 HPKDGH--THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH 675
H +D H T+ V P V Y I I YGG I SP + + +S +G G+
Sbjct: 1568 HIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGP 1627
Query: 676 A-HVGKEAAFTI 708
+G+E T+
Sbjct: 1628 TIQIGEETVITV 1639
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 1290 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 1349
Query: 703 TI 708
T+
Sbjct: 1350 TV 1351
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 1397 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 1456
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 1457 QVKVQGPKGLVEPVDVVDNADGTQTVN 1483
Score = 33.5 bits (73), Expect = 0.85
Identities = 18/61 (29%), Positives = 25/61 (40%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P ++ P +V A G GL A F+IDT G + V G
Sbjct: 1020 YDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEG 1079
Query: 195 P 197
P
Sbjct: 1080 P 1080
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 1789 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 1846
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 1847 KPATFTVN 1854
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 2166 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 2225
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2226 IWTREAGAGGLAIAVEGPSKAEI 2248
Score = 30.7 bits (66), Expect = 6.0
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE---SFDPNRVIVSG--LPTGNIVAQTPINFS 418
K+T G TI VL + SP + S D ++V G L + P +F+
Sbjct: 810 KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFT 869
Query: 419 VVTKDAGVGELDVVCEAMGERRIRLPVDIRRMDTHTECDCVPLYP 553
V K AG G+LDV + + VDI +D H V P
Sbjct: 870 VNAKAAGKGKLDVQFSGLTKGDAVRDVDI--IDHHDNTYTVKYTP 912
>AB208865-1|BAD92102.1| 1342|Homo sapiens gamma filamin variant
protein.
Length = 1342
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL-AHAHV 684
KDG V P P Y + IT+GG PI GSP + V KCSG GL A
Sbjct: 18 KDGSC-TVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRA 76
Query: 685 GKEAAFTIHCAE 720
FT+ C++
Sbjct: 77 RVPQTFTVDCSQ 88
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/67 (40%), Positives = 33/67 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR PT +++ I Y G I GSP+ V +S G GL+H V
Sbjct: 435 KDG-TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPGLSHGMVN 492
Query: 688 KEAAFTI 708
K A FTI
Sbjct: 493 KPATFTI 499
Score = 34.7 bits (76), Expect = 0.37
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G VA P FS
Sbjct: 894 RFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFS 953
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 954 IWTREAGAGGLSIAVEGPSKAEI 976
Score = 33.5 bits (73), Expect = 0.85
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Frame = +2
Query: 209 TARKMLS-NQVWLVASKFTINEVGQSTIEVLHLSKPVSGSP--YTCESFDPNRVIVSGLP 379
TAR ++ N+ + ++ E G + + + + GSP + ++ + V G
Sbjct: 426 TARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPG 485
Query: 380 TGNIVAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
+ + P F++VTKDAG G L + E + I
Sbjct: 486 LSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEI 521
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/57 (35%), Positives = 28/57 (49%)
Frame = +3
Query: 72 HGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSGPGSRALPVRCYQTKSG 242
+ + V+A G GL VNK A+F+I T + V GP S+A + C K G
Sbjct: 475 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGP-SKA-EITCKDNKDG 529
>BX641085-1|CAE46040.1| 2422|Homo sapiens hypothetical protein
protein.
Length = 2422
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Frame = +2
Query: 251 SKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSV 421
+KF E G ++V + PV GSPYT E+ DP++V G + P F++
Sbjct: 835 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 894
Query: 422 VTKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E +I
Sbjct: 895 DTKGAGTGGLGLTVEGPCEAKI 916
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +EV + P+ SP+ E P+RV G P F+VV
Sbjct: 1124 EYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVV 1183
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG+G L + E E +I
Sbjct: 1184 TRGAGIGGLGITVEGPSESKI 1204
Score = 39.9 bits (89), Expect = 0.010
Identities = 25/83 (30%), Positives = 36/83 (43%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y + I + I GSP + S SG GL H VG+
Sbjct: 923 DG-TCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGE 981
Query: 691 EAAFTIHCAEDTSPTVEVERLSN 759
++ C+E + +E +S+
Sbjct: 982 AGLLSVDCSEAGPGALGLEAVSD 1004
Score = 38.7 bits (86), Expect = 0.023
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+ + W G I + P V V P Q+V A G GL+ V + A F ++++G
Sbjct: 356 IAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGF 415
Query: 183 VVSGP 197
+ GP
Sbjct: 416 AIEGP 420
Score = 38.7 bits (86), Expect = 0.023
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +1
Query: 559 YRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
Y + +TY G P+ GSP ++ S K G GL VGK A FTI
Sbjct: 845 YAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 894
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPYTCESFDPNRVIVSGLPTGNI-- 391
+++ N+ V ++ EVG + + ++ + SP PN VS G +
Sbjct: 1595 EIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYG 1654
Query: 392 VAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
VA F++VT+DAG G LD+ E + I
Sbjct: 1655 VANKTATFTIVTEDAGEGGLDLAIEGPSKAEI 1686
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/61 (34%), Positives = 27/61 (44%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P V+ P +V A G GL V K A F+IDT G + V G
Sbjct: 851 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG 910
Query: 195 P 197
P
Sbjct: 911 P 911
Score = 37.5 bits (83), Expect = 0.052
Identities = 19/43 (44%), Positives = 23/43 (53%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
P P Y + ITYGGA I GSP+ + V S K +G GL
Sbjct: 1220 PFAPGDYDVNITYGGAHIPGSPLRVPVKDVVDPSKVKIAGPGL 1262
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/56 (33%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P+ P Y I IT+GG I SP + V + G GL VG+ A F +
Sbjct: 348 PSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVV 403
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH-AHV 684
KDG T+ V P Y I +TYGG I SP + +S +G G+A
Sbjct: 1403 KDG-TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKT 1461
Query: 685 GKEAAFTI 708
G+E F +
Sbjct: 1462 GEEVGFVV 1469
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V+GSP+ ++V G A P FS
Sbjct: 1976 RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFS 2035
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2036 IWTREAGAGGLSIAVEGPSKAEI 2058
Score = 30.3 bits (65), Expect = 7.9
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDV 182
+ ++G I + P +V V + ASG GL ++ + F +DT + E V
Sbjct: 261 IFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGV 320
Query: 183 VVSGP 197
+ GP
Sbjct: 321 TMKGP 325
>AF191633-1|AAF72339.1| 2602|Homo sapiens filamin protein.
Length = 2602
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Frame = +2
Query: 251 SKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSV 421
+KF E G ++V + PV GSPYT E+ DP++V G + P F++
Sbjct: 1004 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Query: 422 VTKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E +I
Sbjct: 1064 DTKGAGTGGLGLTVEGPCEAKI 1085
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +EV + P+ SP+ E P+RV G P F+VV
Sbjct: 1293 EYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVV 1352
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG+G L + E E +I
Sbjct: 1353 TRGAGIGGLGITVEGPSESKI 1373
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y + I + I GSP + S SG GL H VG+
Sbjct: 1092 DG-TCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGE 1150
Query: 691 EAAFTIHCAEDTSPTVEVERLSN 759
+++C+E + +E +S+
Sbjct: 1151 AGLLSVNCSEAGPGALGLEAVSD 1173
Score = 38.7 bits (86), Expect = 0.023
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+ + W G I + P V V P Q+V A G GL+ V + A F ++++G
Sbjct: 525 IAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGF 584
Query: 183 VVSGP 197
+ GP
Sbjct: 585 AIEGP 589
Score = 38.7 bits (86), Expect = 0.023
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +1
Query: 559 YRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
Y + +TY G P+ GSP ++ S K G GL VGK A FTI
Sbjct: 1014 YAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPYTCESFDPNRVIVSGLPTGNI-- 391
+++ N+ V ++ EVG + + ++ + SP PN VS G +
Sbjct: 1775 EIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYG 1834
Query: 392 VAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
VA F++VT+DAG G LD+ E + I
Sbjct: 1835 VANKTATFTIVTEDAGEGGLDLAIEGPSKAEI 1866
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/61 (34%), Positives = 27/61 (44%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P V+ P +V A G GL V K A F+IDT G + V G
Sbjct: 1020 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG 1079
Query: 195 P 197
P
Sbjct: 1080 P 1080
Score = 36.7 bits (81), Expect = 0.091
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
P P Y + ITYGGA I GSP + V S K +G GL
Sbjct: 1389 PFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL 1431
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/56 (33%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P+ P Y I IT+GG I SP + V + G GL VG+ A F +
Sbjct: 517 PSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVV 572
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH-AHV 684
KDG T+ V P Y I +TYGG I SP + +S +G G+A
Sbjct: 1572 KDG-TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKT 1630
Query: 685 GKEAAFTI 708
G+E F +
Sbjct: 1631 GEEVGFVV 1638
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V+GSP+ ++V G A P FS
Sbjct: 2156 RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFS 2215
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2216 IWTREAGAGGLSIAVEGPSKAEI 2238
Score = 30.3 bits (65), Expect = 7.9
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDV 182
+ ++G I + P +V V + ASG GL ++ + F +DT + E V
Sbjct: 430 IFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGV 489
Query: 183 VVSGP 197
+ GP
Sbjct: 490 TMKGP 494
>AF043045-1|AAC33845.1| 2602|Homo sapiens actin-binding protein
homolog ABP-278 protein.
Length = 2602
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Frame = +2
Query: 251 SKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSV 421
+KF E G ++V + PV GSPYT E+ DP++V G + P F++
Sbjct: 1004 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Query: 422 VTKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E +I
Sbjct: 1064 DTKGAGTGGLGLTVEGPCEAKI 1085
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +EV + P+ SP+ E P+RV G P F+VV
Sbjct: 1293 EYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVV 1352
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG+G L + E E +I
Sbjct: 1353 TRGAGIGGLGITVEGPSESKI 1373
Score = 39.9 bits (89), Expect = 0.010
Identities = 25/83 (30%), Positives = 36/83 (43%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y + I + I GSP + S SG GL H VG+
Sbjct: 1092 DG-TCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGE 1150
Query: 691 EAAFTIHCAEDTSPTVEVERLSN 759
++ C+E + +E +S+
Sbjct: 1151 AGLLSVDCSEAGPGALGLEAVSD 1173
Score = 38.7 bits (86), Expect = 0.023
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+ + W G I + P V V P Q+V A G GL+ V + A F ++++G
Sbjct: 525 IAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGF 584
Query: 183 VVSGP 197
+ GP
Sbjct: 585 AIEGP 589
Score = 38.7 bits (86), Expect = 0.023
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +1
Query: 559 YRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
Y + +TY G P+ GSP ++ S K G GL VGK A FTI
Sbjct: 1014 YAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPYTCESFDPNRVIVSGLPTGNI-- 391
+++ N+ V ++ EVG + + ++ + SP PN VS G +
Sbjct: 1775 EIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYG 1834
Query: 392 VAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
VA F++VT+DAG G LD+ E + I
Sbjct: 1835 VANKTATFTIVTEDAGEGGLDLAIEGPSKAEI 1866
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/61 (34%), Positives = 27/61 (44%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P V+ P +V A G GL V K A F+IDT G + V G
Sbjct: 1020 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG 1079
Query: 195 P 197
P
Sbjct: 1080 P 1080
Score = 36.7 bits (81), Expect = 0.091
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
P P Y + ITYGGA I GSP + V S K +G GL
Sbjct: 1389 PFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL 1431
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/56 (33%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P+ P Y I IT+GG I SP + V + G GL VG+ A F +
Sbjct: 517 PSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVV 572
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH-AHV 684
KDG T+ V P Y I +TYGG I SP + +S +G G+A
Sbjct: 1572 KDG-TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKT 1630
Query: 685 GKEAAFTI 708
G+E F +
Sbjct: 1631 GEEVGFVV 1638
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V+GSP+ ++V G A P FS
Sbjct: 2156 RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFS 2215
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2216 IWTREAGAGGLSIAVEGPSKAEI 2238
Score = 30.3 bits (65), Expect = 7.9
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDV 182
+ ++G I + P +V V + ASG GL ++ + F +DT + E V
Sbjct: 430 IFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGV 489
Query: 183 VVSGP 197
+ GP
Sbjct: 490 TMKGP 494
>AF042166-1|AAC39842.1| 2602|Homo sapiens beta-filamin protein.
Length = 2602
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Frame = +2
Query: 251 SKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSV 421
+KF E G ++V + PV GSPYT E+ DP++V G + P F++
Sbjct: 1004 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Query: 422 VTKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E +I
Sbjct: 1064 DTKGAGTGGLGLTVEGPCEAKI 1085
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +EV + P+ SP+ E P+RV G P F+VV
Sbjct: 1293 EYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVV 1352
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG+G L + E E +I
Sbjct: 1353 TRGAGIGGLGITVEGPSESKI 1373
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y + I + I GSP + S SG GL H VG+
Sbjct: 1092 DG-TCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGE 1150
Query: 691 EAAFTIHCAEDTSPTVEVERLSN 759
+++C+E + +E +S+
Sbjct: 1151 AGLLSVNCSEAGPGALGLEAVSD 1173
Score = 38.7 bits (86), Expect = 0.023
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+ + W G I + P V V P Q+V A G GL+ V + A F ++++G
Sbjct: 525 IAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGF 584
Query: 183 VVSGP 197
+ GP
Sbjct: 585 AIEGP 589
Score = 38.7 bits (86), Expect = 0.023
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +1
Query: 559 YRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
Y + +TY G P+ GSP ++ S K G GL VGK A FTI
Sbjct: 1014 YAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPYTCESFDPNRVIVSGLPTGNI-- 391
+++ N+ V ++ EVG + + ++ + SP PN VS G +
Sbjct: 1775 EIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYG 1834
Query: 392 VAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
VA F++VT+DAG G LD+ E + I
Sbjct: 1835 VANKTATFTIVTEDAGEGGLDLAIEGPSKAEI 1866
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/61 (34%), Positives = 27/61 (44%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P V+ P +V A G GL V K A F+IDT G + V G
Sbjct: 1020 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG 1079
Query: 195 P 197
P
Sbjct: 1080 P 1080
Score = 36.7 bits (81), Expect = 0.091
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
P P Y + ITYGGA I GSP + V S K +G GL
Sbjct: 1389 PFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL 1431
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/56 (33%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P+ P Y I IT+GG I SP + V + G GL VG+ A F +
Sbjct: 517 PSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVV 572
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH-AHV 684
KDG T+ V P Y I +TYGG I SP + +S +G G+A
Sbjct: 1572 KDG-TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKT 1630
Query: 685 GKEAAFTI 708
G+E F +
Sbjct: 1631 GEEVGFVV 1638
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V+GSP+ ++V G A P FS
Sbjct: 2156 RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFS 2215
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2216 IWTREAGAGGLSIAVEGPSKAEI 2238
Score = 30.3 bits (65), Expect = 7.9
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDV 182
+ ++G I + P +V V + ASG GL ++ + F +DT + E V
Sbjct: 430 IFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGV 489
Query: 183 VVSGP 197
+ GP
Sbjct: 490 TMKGP 494
>AB209889-1|BAD93126.1| 1613|Homo sapiens filamin B, beta (actin
binding protein 278) variant protein.
Length = 1613
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Frame = +2
Query: 251 SKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSV 421
+KF E G ++V + PV GSPYT E+ DP++V G + P F++
Sbjct: 15 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 74
Query: 422 VTKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E +I
Sbjct: 75 DTKGAGTGGLGLTVEGPCEAKI 96
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +EV + P+ SP+ E P+RV G P F+VV
Sbjct: 304 EYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVV 363
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG+G L + E E +I
Sbjct: 364 TRGAGIGGLGITVEGPSESKI 384
Score = 39.9 bits (89), Expect = 0.010
Identities = 25/83 (30%), Positives = 36/83 (43%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y + I + I GSP + S SG GL H VG+
Sbjct: 103 DG-TCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGE 161
Query: 691 EAAFTIHCAEDTSPTVEVERLSN 759
++ C+E + +E +S+
Sbjct: 162 AGLLSVDCSEAGPGALGLEAVSD 184
Score = 38.7 bits (86), Expect = 0.023
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +1
Query: 559 YRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
Y + +TY G P+ GSP ++ S K G GL VGK A FTI
Sbjct: 25 YAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 74
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPYTCESFDPNRVIVSGLPTGNI-- 391
+++ N+ V ++ EVG + + ++ + SP PN VS G +
Sbjct: 786 EIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYG 845
Query: 392 VAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
VA F++VT+DAG G LD+ E + I
Sbjct: 846 VANKTATFTIVTEDAGEGGLDLAIEGPSKAEI 877
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/61 (34%), Positives = 27/61 (44%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P V+ P +V A G GL V K A F+IDT G + V G
Sbjct: 31 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG 90
Query: 195 P 197
P
Sbjct: 91 P 91
Score = 36.7 bits (81), Expect = 0.091
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
P P Y + ITYGGA I GSP + V S K +G GL
Sbjct: 400 PFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL 442
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH-AHV 684
KDG T+ V P Y I +TYGG I SP + +S +G G+A
Sbjct: 583 KDG-TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKT 641
Query: 685 GKEAAFTI 708
G+E F +
Sbjct: 642 GEEVGFVV 649
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V+GSP+ ++V G A P FS
Sbjct: 1167 RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFS 1226
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 1227 IWTREAGAGGLSIAVEGPSKAEI 1249
>AB191258-1|BAD52434.1| 2591|Homo sapiens filamin B protein.
Length = 2591
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Frame = +2
Query: 251 SKFTINEVGQSTIEVLHLSKPVSGSPYTCESF---DPNRVIVSGLPTGNIVAQTPINFSV 421
+KF E G ++V + PV GSPYT E+ DP++V G + P F++
Sbjct: 1004 AKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Query: 422 VTKDAGVGELDVVCEAMGERRI 487
TK AG G L + E E +I
Sbjct: 1064 DTKGAGTGGLGLTVEGPCEAKI 1085
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +EV + P+ SP+ E P+RV G P F+VV
Sbjct: 1293 EYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVV 1352
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG+G L + E E +I
Sbjct: 1353 TRGAGIGGLGITVEGPSESKI 1373
Score = 39.9 bits (89), Expect = 0.010
Identities = 25/83 (30%), Positives = 36/83 (43%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG T V PT P Y + I + I GSP + S SG GL H VG+
Sbjct: 1092 DG-TCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGE 1150
Query: 691 EAAFTIHCAEDTSPTVEVERLSN 759
++ C+E + +E +S+
Sbjct: 1151 AGLLSVDCSEAGPGALGLEAVSD 1173
Score = 38.7 bits (86), Expect = 0.023
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDV 182
+ + W G I + P V V P Q+V A G GL+ V + A F ++++G
Sbjct: 525 IAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGF 584
Query: 183 VVSGP 197
+ GP
Sbjct: 585 AIEGP 589
Score = 38.7 bits (86), Expect = 0.023
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +1
Query: 559 YRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
Y + +TY G P+ GSP ++ S K G GL VGK A FTI
Sbjct: 1014 YAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTI 1063
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = +2
Query: 218 KMLSNQVWLVASKFTINEVGQSTIEVLHLSKPVSGSPYTCESFDPNRVIVSGLPTGNI-- 391
+++ N+ V ++ EVG + + ++ + SP PN VS G +
Sbjct: 1764 EIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYG 1823
Query: 392 VAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
VA F++VT+DAG G LD+ E + I
Sbjct: 1824 VANKTATFTIVTEDAGEGGLDLAIEGPSKAEI 1855
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/61 (34%), Positives = 27/61 (44%)
Frame = +3
Query: 15 WSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSG 194
+ G P+ P V+ P +V A G GL V K A F+IDT G + V G
Sbjct: 1020 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG 1079
Query: 195 P 197
P
Sbjct: 1080 P 1080
Score = 36.7 bits (81), Expect = 0.091
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGL 669
P P Y + ITYGGA I GSP + V S K +G GL
Sbjct: 1389 PFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL 1431
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/56 (33%), Positives = 25/56 (44%)
Frame = +1
Query: 541 PTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAFTI 708
P+ P Y I IT+GG I SP + V + G GL VG+ A F +
Sbjct: 517 PSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVV 572
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH-AHV 684
KDG T+ V P Y I +TYGG I SP + +S +G G+A
Sbjct: 1572 KDG-TYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKT 1630
Query: 685 GKEAAFTI 708
G+E F +
Sbjct: 1631 GEEVGFVV 1638
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V+GSP+ ++V G A P FS
Sbjct: 2145 RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFS 2204
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 2205 IWTREAGAGGLSIAVEGPSKAEI 2227
Score = 30.3 bits (65), Expect = 7.9
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Frame = +3
Query: 9 LLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQ--AQVNKVASFSIDTLGRPAREFDV 182
+ ++G I + P +V V + ASG GL ++ + F +DT + E V
Sbjct: 430 IFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGV 489
Query: 183 VVSGP 197
+ GP
Sbjct: 490 TMKGP 494
>AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein.
Length = 1455
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPY---TCESFDPNRVIVSGLPTGNIVAQTPINFSVV 424
++T E G +++V + PV SP+ E DP+RV V G + P F+V
Sbjct: 136 EYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVE 195
Query: 425 TKDAGVGELDVVCEAMGERRI 487
T+ AG G L + E E ++
Sbjct: 196 TRGAGTGGLGLAVEGPSEAKM 216
Score = 40.3 bits (90), Expect = 0.007
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGK 690
DG TH + P P Y + I YGG P+ P L V +S +C G G+ V +
Sbjct: 30 DG-THTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFR 88
Query: 691 EA 696
EA
Sbjct: 89 EA 90
Score = 37.9 bits (84), Expect = 0.039
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLA 672
KDG V P Y + +TYGG + GSP + V +S KCSG GL+
Sbjct: 222 KDGSCS-VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLS 275
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 1002 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 1061
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 1062 GVPAEFSIWTRE 1073
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Frame = +1
Query: 502 HPKDGH--THRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAH 675
H +D H T+ V P V Y I I YGG I SP + + +S +G G+
Sbjct: 411 HIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGP 470
Query: 676 A-HVGKEAAFTI 708
+G+E T+
Sbjct: 471 TIQIGEETVITV 482
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/62 (25%), Positives = 27/62 (43%)
Frame = +1
Query: 523 HRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVGKEAAF 702
++V P + + +TY G+P+ SP + V G S + G G+ K F
Sbjct: 133 YKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKF 192
Query: 703 TI 708
T+
Sbjct: 193 TV 194
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Frame = +3
Query: 3 LTLLWSGAPIDREPLLVDVHPPHHGQEVAASGLGLYQAQV--NKVASFSIDTLGRPAREF 176
L + + G + P V VH +V SG GL V N SF +DT
Sbjct: 240 LNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL 299
Query: 177 DVVVSGPGSRALPVRCYQTKSGLLQAN 257
V V GP PV G N
Sbjct: 300 QVKVQGPKGLVEPVDVVDNADGTQTVN 326
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 632 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 689
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 690 KPATFTVN 697
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 1009 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 1068
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 1069 IWTREAGAGGLAIAVEGPSKAEI 1091
>X70084-1|CAA49689.1| 431|Homo sapiens filamin protein.
Length = 431
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/67 (40%), Positives = 33/67 (49%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR PT +++ I Y G I GSP+ V +S G GL+H V
Sbjct: 148 KDG-TITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPGLSHGMVN 205
Query: 688 KEAAFTI 708
K A FTI
Sbjct: 206 KPATFTI 212
Score = 33.5 bits (73), Expect = 0.85
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Frame = +2
Query: 209 TARKMLS-NQVWLVASKFTINEVGQSTIEVLHLSKPVSGSP--YTCESFDPNRVIVSGLP 379
TAR ++ N+ + ++ E G + + + + GSP + ++ + V G
Sbjct: 139 TARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPG 198
Query: 380 TGNIVAQTPINFSVVTKDAGVGELDVVCEAMGERRI 487
+ + P F++VTKDAG G L + E + I
Sbjct: 199 LSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEI 234
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/57 (35%), Positives = 28/57 (49%)
Frame = +3
Query: 72 HGQEVAASGLGLYQAQVNKVASFSIDTLGRPAREFDVVVSGPGSRALPVRCYQTKSG 242
+ + V+A G GL VNK A+F+I T + V GP S+A + C K G
Sbjct: 188 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGP-SKA-EITCKDNKDG 242
>BX664723-4|CAI43200.2| 281|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 281
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 134 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 193
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 194 GVPAEFSIWTRE 205
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 141 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 200
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 201 IWTREAGAGGLAIAVEGPSKAEI 223
>BC109289-1|AAI09290.3| 307|Homo sapiens FLNA protein protein.
Length = 307
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 111 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 170
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 171 GVPAEFSIWTRE 182
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 118 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 177
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 178 IWTREAGAGGLAIAVEGPSKAEI 200
>BC067111-1|AAH67111.1| 983|Homo sapiens FLNA protein protein.
Length = 983
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 530 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 589
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 590 GVPAEFSIWTRE 601
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 160 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 217
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 218 KPATFTVN 225
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 537 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 596
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 597 IWTREAGAGGLAIAVEGPSKAEI 619
>BC014654-1|AAH14654.1| 838|Homo sapiens FLNA protein protein.
Length = 838
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +1
Query: 511 DGHTHRVRLRPTVPSHYRIYITYGGAPILGSP--ISLGVLSGRSSSAAKCSGTGLAHAHV 684
+ HT+ +R P + + + Y G + GSP ++G L + + G GL A
Sbjct: 385 ENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEA 444
Query: 685 GKEAAFTIHCAE 720
G A F+I E
Sbjct: 445 GVPAEFSIWTRE 456
Score = 31.5 bits (68), Expect = 3.4
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 15 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 72
Query: 688 KEAAFTIH 711
K A FT++
Sbjct: 73 KPATFTVN 80
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V GSP+ ++V G A P FS
Sbjct: 392 RFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFS 451
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 452 IWTREAGAGGLAIAVEGPSKAEI 474
>AL137574-1|CAB70818.1| 729|Homo sapiens hypothetical protein
protein.
Length = 729
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V+GSP+ ++V G A P FS
Sbjct: 283 RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFS 342
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 343 IWTREAGAGGLSIAVEGPSKAEI 365
>BX664723-5|CAI43201.1| 231|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 231
Score = 31.9 bits (69), Expect = 2.6
Identities = 27/86 (31%), Positives = 38/86 (44%)
Frame = +1
Query: 508 KDGHTHRVRLRPTVPSHYRIYITYGGAPILGSPISLGVLSGRSSSAAKCSGTGLAHAHVG 687
KDG T VR P+ + + I Y I GSP+ V + G GL H V
Sbjct: 106 KDG-TVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHVTAYGPGLTHGVVN 163
Query: 688 KEAAFTIHCAEDTSPTVEVERLSNDK 765
K A FT++ +D + R+S+ K
Sbjct: 164 KPATFTVN-TKDAGEGDDSMRMSHLK 188
>AF238609-1|AAF97046.1| 672|Homo sapiens filamen B protein.
Length = 672
Score = 31.9 bits (69), Expect = 2.6
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 254 KFTINEVGQSTIEVLHLSKPVSGSPYTCE-----SFDPNRVIVSGLPTGNIVAQTPINFS 418
+F E+G T+ V + + V+GSP+ ++V G A P FS
Sbjct: 226 RFVPQEMGVHTVSVNYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFS 285
Query: 419 VVTKDAGVGELDVVCEAMGERRI 487
+ T++AG G L + E + I
Sbjct: 286 IWTREAGAGGLSIAVEGPSKAEI 308
>Y09321-1|CAA70499.1| 801|Homo sapiens TBP associated factor
protein.
Length = 801
Score = 31.5 bits (68), Expect = 3.4
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Frame = +2
Query: 299 HLSKPVSGSPYTCESFDPNRVI--VSGLPTGNIVAQTPINFSVVTKDAGVGELDV 457
H+ KPV G+P + P V+ +G+PTG+ Q F VV + +G E V
Sbjct: 428 HICKPVIGTPVQIKLAQPGPVLSQPAGIPTGSSSKQLFSLFHVVQQPSGGNEKQV 482
>AB234096-1|BAF51561.1| 867|Homo sapiens TATA box binding protein
(TBP)-associated factor 4B protein.
Length = 867
Score = 31.5 bits (68), Expect = 3.4
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Frame = +2
Query: 299 HLSKPVSGSPYTCESFDPNRVI--VSGLPTGNIVAQTPINFSVVTKDAGVGELDV 457
H+ KPV G+P + P V+ +G+PTG+ Q F VV + +G E V
Sbjct: 494 HICKPVIGTPVQIKLAQPGPVLSQPAGIPTGSSSKQLFSLFHVVQQPSGGNEKQV 548
>BC031054-1|AAH31054.2| 635|Homo sapiens OSGIN2 protein protein.
Length = 635
Score = 31.1 bits (67), Expect = 4.5
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
Frame = -3
Query: 214 GSAREPGPETTTSNSRAGRP-RVSILNDATLLT*AWYKPRPEAATSCPWCGGCT 56
G AR G T +GRP R + +A T A RP + CPWC C+
Sbjct: 43 GEARGRGARQTPRPRASGRPERAASPGEAEAAT-AAALGRPSRSAPCPWCCRCS 95
>X85018-1|CAA59380.1| 559|Homo sapiens UDP-GalNAc:polypeptide
N-acetylgalactosaminyl transferase protein.
Length = 559
Score = 30.3 bits (65), Expect = 7.9
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Frame = -1
Query: 324 LPDTGLDRCKTSIV--LCPTSLIVNLLATSQTWFDNILRAVLESQVQRRPRRIPEQV 160
LPD L+ CKT + PT+ +V ++ ++ W +LR V S + R PR + E++
Sbjct: 98 LPDVRLEGCKTKVYPDNLPTTSVV-IVFHNEAW-STLLRTV-HSVINRSPRHMIEEI 151
>U41514-1|AAC50327.1| 559|Homo sapiens UDP-GalNAc:polypeptide
N-acetylgalactosaminyltransferase protein.
Length = 559
Score = 30.3 bits (65), Expect = 7.9
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Frame = -1
Query: 324 LPDTGLDRCKTSIV--LCPTSLIVNLLATSQTWFDNILRAVLESQVQRRPRRIPEQV 160
LPD L+ CKT + PT+ +V ++ ++ W +LR V S + R PR + E++
Sbjct: 98 LPDVRLEGCKTKVYPDNLPTTSVV-IVFHNEAW-STLLRTV-HSVINRSPRHMIEEI 151
>BC038440-1|AAH38440.1| 499|Homo sapiens GALNT1 protein protein.
Length = 499
Score = 30.3 bits (65), Expect = 7.9
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Frame = -1
Query: 324 LPDTGLDRCKTSIV--LCPTSLIVNLLATSQTWFDNILRAVLESQVQRRPRRIPEQV 160
LPD L+ CKT + PT+ +V ++ ++ W +LR V S + R PR + E++
Sbjct: 38 LPDVRLEGCKTKVYPDNLPTTSVV-IVFHNEAW-STLLRTV-HSVINRSPRHMIEEI 91
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 134,145,403
Number of Sequences: 237096
Number of extensions: 3329929
Number of successful extensions: 8526
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 7483
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8471
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9199990470
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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