Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV30980
(792 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,... 139 8e-32
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-... 138 1e-31
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub... 131 2e-29
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub... 127 4e-28
UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub... 126 8e-28
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub... 123 6e-27
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub... 119 1e-25
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub... 113 5e-24
UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whol... 112 8e-24
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=... 109 1e-22
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 109 1e-22
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP... 108 1e-22
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp... 108 2e-22
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 104 3e-21
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph... 102 1e-20
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp... 100 4e-20
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 100 5e-20
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al... 96 1e-18
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 93 5e-18
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp... 91 4e-17
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 90 7e-17
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al... 89 9e-17
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 88 2e-16
UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 87 6e-16
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 85 1e-15
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 85 2e-15
UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8; Chla... 84 3e-15
UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 83 6e-15
UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 82 2e-14
UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1; Proch... 80 7e-14
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 79 2e-13
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (... 76 9e-13
UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 75 2e-12
UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase (Lipoam... 74 4e-12
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote... 74 4e-12
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 74 4e-12
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 74 5e-12
UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridiu... 74 5e-12
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 73 6e-12
UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2; Bacte... 73 8e-12
UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 72 1e-11
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 71 4e-11
UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha... 70 6e-11
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E... 70 6e-11
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R... 70 8e-11
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 69 2e-10
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp... 69 2e-10
UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomon... 68 2e-10
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 68 3e-10
UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 67 4e-10
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 67 5e-10
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor... 67 5e-10
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 67 5e-10
UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 66 1e-09
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 65 2e-09
UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomon... 65 2e-09
UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3; Actin... 65 2e-09
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 64 5e-09
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ... 63 7e-09
UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2; Alphap... 62 2e-08
UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1; R... 61 4e-08
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 60 5e-08
UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3; Prote... 60 6e-08
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ... 60 6e-08
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 60 6e-08
UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4; Actinomyce... 60 8e-08
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 60 8e-08
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 60 8e-08
UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n... 59 1e-07
UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=... 59 1e-07
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 59 1e-07
UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=... 59 1e-07
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 58 3e-07
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 56 3e-07
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 57 6e-07
UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1; ... 56 8e-07
UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12; Bacteria|... 56 8e-07
UniRef50_Q0ET31 Cluster: Dehydrogenase, E1 component; n=1; Therm... 56 1e-06
UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase alpha-s... 55 2e-06
UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha s... 52 1e-05
UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2; Rhodo... 52 2e-05
UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, al... 51 3e-05
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 51 3e-05
UniRef50_A2C5U8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 50 5e-05
UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alp... 49 2e-04
UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,... 48 3e-04
UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3; Bacte... 48 3e-04
UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit... 48 4e-04
UniRef50_UPI0000384B37 Cluster: COG1071: Pyruvate/2-oxoglutarate... 47 6e-04
UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 46 0.001
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 44 0.004
UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7; Mycoba... 43 0.008
UniRef50_A5LD62 Cluster: Probable transketolase; n=1; Streptococ... 42 0.018
UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 42 0.018
UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 42 0.023
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 41 0.031
UniRef50_Q1IGG4 Cluster: Putative FecR-like transmembrane sensor... 41 0.031
UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alp... 41 0.041
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 41 0.041
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 41 0.041
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 40 0.054
UniRef50_Q9NYV4 Cluster: Cell division cycle 2-related protein k... 40 0.054
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 40 0.072
UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component, al... 40 0.072
UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep: ... 40 0.095
UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, al... 40 0.095
UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1 compo... 39 0.17
UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway sig... 39 0.17
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 38 0.22
UniRef50_A5ZA31 Cluster: Putative uncharacterized protein; n=1; ... 38 0.22
UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n... 38 0.22
UniRef50_A1I7J5 Cluster: Putative transketolase, N-terminal subu... 38 0.29
UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R... 38 0.38
UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 38 0.38
UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component sub... 38 0.38
UniRef50_A0LHU2 Cluster: Transketolase domain protein; n=1; Synt... 37 0.50
UniRef50_Q4KXE0 Cluster: Cold acclimation induced protein 2-1; n... 37 0.50
UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4; ... 37 0.50
UniRef50_Q97NC3 Cluster: Transketolase, N-terminal subunit; n=29... 37 0.67
UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid dehydrog... 36 0.88
UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, ... 36 0.88
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 36 0.88
UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto... 36 0.88
UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum... 36 0.88
UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component sub... 36 0.88
UniRef50_Q89J58 Cluster: Transketolase; n=7; Bacteria|Rep: Trans... 36 1.2
UniRef50_A0TAK4 Cluster: Transketolase-like; n=1; Burkholderia a... 36 1.2
UniRef50_Q01916 Cluster: IpiB3 protein precursor; n=3; Phytophth... 36 1.2
UniRef50_Q9V1I2 Cluster: Tkt1 transketolase N-terminal section; ... 36 1.2
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 36 1.5
UniRef50_Q6MHR5 Cluster: InterPro: Transketolase; n=1; Bdellovib... 36 1.5
UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, al... 36 1.5
UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto... 36 1.5
UniRef50_Q9FM99 Cluster: Similarity to carbonic anhydrase; n=1; ... 36 1.5
UniRef50_A4RA81 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0
UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 35 2.0
UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component sub... 35 2.7
UniRef50_Q7TZU3 Cluster: PE-PGRS FAMILY PROTEIN; n=28; Mycobacte... 35 2.7
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 35 2.7
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 35 2.7
UniRef50_Q5NA48 Cluster: Putative chromatin remodeling factor CH... 35 2.7
UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component sub... 35 2.7
UniRef50_Q4A2S6 Cluster: Putative membrane protein precursor; n=... 34 3.6
UniRef50_Q8KWB9 Cluster: RB123; n=1; Ruegeria sp. PR1b|Rep: RB12... 34 3.6
UniRef50_Q756F4 Cluster: DNA repair and recombination protein RA... 34 3.6
UniRef50_UPI0000DB7674 Cluster: PREDICTED: hypothetical protein;... 34 4.7
UniRef50_Q9DYE3 Cluster: Membrane virion glycoprotein 150; n=2; ... 34 4.7
UniRef50_Q2IMK5 Cluster: DnaJ like heat shock protein with tetra... 34 4.7
UniRef50_Q2CJ96 Cluster: Putative transketolase alpha subunit pr... 34 4.7
UniRef50_Q02BA9 Cluster: Transketolase domain protein; n=1; Soli... 34 4.7
UniRef50_A3U4U6 Cluster: Transketolase, N-terminal subunit; n=19... 34 4.7
UniRef50_A0H3S4 Cluster: Putative uncharacterized protein; n=1; ... 34 4.7
UniRef50_Q41071 Cluster: Arabinogalactan-like protein; n=2; Pina... 34 4.7
UniRef50_Q9VDD2 Cluster: CG17299-PF, isoform F; n=18; Diptera|Re... 34 4.7
UniRef50_Q8INB9 Cluster: RAC serine/threonine-protein kinase; n=... 34 4.7
UniRef50_UPI000069F43F Cluster: Short transient receptor potenti... 33 6.2
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 33 6.2
UniRef50_Q07IS1 Cluster: Transketolase, central region; n=1; Rho... 33 6.2
UniRef50_A6GFK2 Cluster: Modular polyketide synthase; n=1; Plesi... 33 6.2
UniRef50_A0L593 Cluster: Transketolase domain protein; n=2; Prot... 33 6.2
UniRef50_O15032 Cluster: FERM and PDZ domain-containing protein ... 33 6.2
UniRef50_Q7SBI9 Cluster: Predicted protein; n=1; Neurospora cras... 33 6.2
UniRef50_Q8ZW78 Cluster: Transketolase; n=5; Thermoproteaceae|Re... 33 6.2
UniRef50_A0RTR4 Cluster: Transketolase, N-terminal subunit; n=1;... 33 6.2
UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 33 6.2
UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 33 6.2
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 33 8.2
UniRef50_Q7NNH9 Cluster: Glr0432 protein; n=1; Gloeobacter viola... 33 8.2
UniRef50_Q2Y5G9 Cluster: TonB-like; n=1; Nitrosospira multiformi... 33 8.2
UniRef50_Q1QHE7 Cluster: OmpA/MotB precursor; n=2; Nitrobacter|R... 33 8.2
UniRef50_A6C1X9 Cluster: Transketolase-like protein; n=1; Planct... 33 8.2
UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1; Novos... 33 8.2
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 33 8.2
UniRef50_Q9VEJ1 Cluster: CG5836-PA; n=10; Eumetazoa|Rep: CG5836-... 33 8.2
UniRef50_Q4E016 Cluster: Putative uncharacterized protein; n=2; ... 33 8.2
UniRef50_A7F3W9 Cluster: Putative uncharacterized protein; n=2; ... 33 8.2
UniRef50_P03073 Cluster: Large T antigen; n=4; root|Rep: Large T... 33 8.2
UniRef50_Q5H9T9 Cluster: Uncharacterized protein C14orf155; n=4;... 33 8.2
>UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 378
Score = 139 bits (336), Expect = 8e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKY 687
AYL GV++ GVL+ELTGRRTGC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY
Sbjct: 249 AYLRGVTLHGVLAELTGRRTGCAKGKGGSMHMYCKNFYGGNGIVGAQVPLGAGIALALKY 308
Query: 688 RADGGVTFALYGDGAANQGQLFEAY 762
V +LYGDGAANQGQ+FEAY
Sbjct: 309 TDKKNVCISLYGDGAANQGQVFEAY 333
Score = 113 bits (272), Expect = 5e-24
Identities = 47/88 (53%), Positives = 65/88 (73%)
Frame = +2
Query: 245 IRNQPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYS 424
+ P+KLHKL++GP ++ LT ++AL Y ++ +RR+ETA+ LYK K +RGFCHLYS
Sbjct: 161 LTTNPFKLHKLEEGPKKTSVLTKDEALDYYHKMQTIRRMETAAATLYKSKEVRGFCHLYS 220
Query: 425 GQEAVAVGMRAAMRDADSVITAYRCHGW 508
GQEA AVG+ + + D+VITAYR HGW
Sbjct: 221 GQEACAVGISSVLTPDDAVITAYRAHGW 248
>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
- Drosophila melanogaster (Fruit fly)
Length = 479
Score = 138 bits (334), Expect = 1e-31
Identities = 60/84 (71%), Positives = 70/84 (83%)
Frame = +1
Query: 511 YLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYR 690
YLMGVS+ +++EL G RTGCSRGKGGSMH+Y FYGGNGIVGAQVPLGAG+ AH YR
Sbjct: 127 YLMGVSLYEIMAELFGVRTGCSRGKGGSMHMYSDKFYGGNGIVGAQVPLGAGIGLAHSYR 186
Query: 691 ADGGVTFALYGDGAANQGQLFEAY 762
D GV+ LYGDGAANQGQ+FE++
Sbjct: 187 KDNGVSVVLYGDGAANQGQIFESF 210
Score = 115 bits (277), Expect = 1e-24
Identities = 50/83 (60%), Positives = 61/83 (73%)
Frame = +2
Query: 260 YKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 439
+K + L+ GP L+ EDAL +Y Q+ LRR ET +GN YKE+ IRGFCHLY+GQEAV
Sbjct: 43 FKCYDLENGPTMDVELSREDALTMYTQMLELRRFETVAGNYYKERKIRGFCHLYNGQEAV 102
Query: 440 AVGMRAAMRDADSVITAYRCHGW 508
AVGM+ +R DSVITAYRCH W
Sbjct: 103 AVGMKQRLRSCDSVITAYRCHAW 125
>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial precursor;
n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha, somatic form, mitochondrial
precursor - Homo sapiens (Human)
Length = 390
Score = 131 bits (317), Expect = 2e-29
Identities = 60/98 (61%), Positives = 74/98 (75%), Gaps = 3/98 (3%)
Frame = +1
Query: 478 SDHRVSLSR---MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 648
+DH ++ R + G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 111 TDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
Query: 649 VPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEAY 762
VPLGAG+A A KY V LYGDGAANQGQ+FEAY
Sbjct: 171 VPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAY 208
Score = 97.9 bits (233), Expect = 3e-19
Identities = 43/87 (49%), Positives = 57/87 (65%)
Frame = +2
Query: 266 LHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 445
LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA V
Sbjct: 43 LHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCV 102
Query: 446 GMRAAMRDADSVITAYRCHGWLISWAL 526
G+ A + D +ITAYR HG+ + L
Sbjct: 103 GLEAGINPTDHLITAYRAHGFTFTRGL 129
>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, mitochondrial precursor; n=34;
Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 420
Score = 127 bits (306), Expect = 4e-28
Identities = 56/84 (66%), Positives = 68/84 (80%)
Frame = +1
Query: 511 YLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYR 690
++ G SV VL+EL GRR G S GKGGSMHLY FYGGNGIVGAQVPLGAG+AFAH+Y+
Sbjct: 145 FMRGASVKAVLAELMGRRAGVSYGKGGSMHLYAPGFYGGNGIVGAQVPLGAGLAFAHQYK 204
Query: 691 ADGGVTFALYGDGAANQGQLFEAY 762
+ +F LYGDGA+NQGQ+FE++
Sbjct: 205 NEDACSFTLYGDGASNQGQVFESF 228
Score = 81.4 bits (192), Expect = 2e-14
Identities = 37/74 (50%), Positives = 50/74 (67%)
Frame = +2
Query: 287 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 466
P S + L++Y+ + I+RR+E A LYK K IRGFCHL GQEA+AVG+ A+
Sbjct: 70 PDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGIENAIT 129
Query: 467 DADSVITAYRCHGW 508
DS+IT+YRCHG+
Sbjct: 130 KLDSIITSYRCHGF 143
>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha type I, mitochondrial precursor; n=10;
cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha type I, mitochondrial precursor
- Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Length = 396
Score = 126 bits (303), Expect = 8e-28
Identities = 53/87 (60%), Positives = 68/87 (78%)
Frame = +2
Query: 248 RNQPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG 427
+ +P+KLHKLD GP + +T EDA+ Y Q+ +RR+E+A+GNLYKEK +RGFCHLYSG
Sbjct: 33 QTKPFKLHKLDSGPDINVHVTKEDAVHYYTQMLTIRRMESAAGNLYKEKKVRGFCHLYSG 92
Query: 428 QEAVAVGMRAAMRDADSVITAYRCHGW 508
QEA AVG +AAM D+ +TAYRCHGW
Sbjct: 93 QEACAVGTKAAMDAGDAAVTAYRCHGW 119
Score = 122 bits (293), Expect = 1e-26
Identities = 57/83 (68%), Positives = 63/83 (75%)
Frame = +1
Query: 511 YLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYR 690
YL G SV VL ELTGR TG GKGGSMH+YG NFYGGNGIVGAQ PLG G+AFA KYR
Sbjct: 121 YLSGSSVAKVLCELTGRITGNVYGKGGSMHMYGENFYGGNGIVGAQQPLGTGIAFAMKYR 180
Query: 691 ADGGVTFALYGDGAANQGQLFEA 759
+ V ++GDGA NQGQLFE+
Sbjct: 181 KEKNVCITMFGDGATNQGQLFES 203
>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor; n=33; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 393
Score = 123 bits (296), Expect = 6e-27
Identities = 57/82 (69%), Positives = 65/82 (79%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQVPLGAGVAFAHKYRA 693
G ++ SEL GR+TGCS GKGGSMH Y ++ FYGG+GIVGAQ+PLG G+AFA KY
Sbjct: 130 GGKLVDAFSELMGRKTGCSHGKGGSMHFYKKDASFYGGHGIVGAQIPLGCGLAFAQKYNK 189
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
D VTFALYGDGAANQGQLFEA
Sbjct: 190 DEAVTFALYGDGAANQGQLFEA 211
Score = 87.8 bits (208), Expect = 3e-16
Identities = 40/82 (48%), Positives = 57/82 (69%)
Frame = +2
Query: 257 PYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 436
P+ H L + P+ S +SE+ L + + +RR+E A+ +LYK K+IRGFCHLY GQEA
Sbjct: 43 PFTSH-LCESPSRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEA 101
Query: 437 VAVGMRAAMRDADSVITAYRCH 502
+AVGM AA+ D++IT+YR H
Sbjct: 102 LAVGMEAAITKKDAIITSYRDH 123
>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Zymomonas
mobilis
Length = 354
Score = 119 bits (286), Expect = 1e-25
Identities = 54/83 (65%), Positives = 67/83 (80%), Gaps = 2/83 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G+ V++ELTGR +G S GKGGSMH++ F+GGNGIVGAQVPLGAG+AFAHKYR
Sbjct: 107 GIDPKIVMAELTGRASGISHGKGGSMHMFSTEHKFFGGNGIVGAQVPLGAGLAFAHKYRN 166
Query: 694 DGGVTFALYGDGAANQGQLFEAY 762
DGG + A +GDG+ANQGQ++EAY
Sbjct: 167 DGGCSAAYFGDGSANQGQVYEAY 189
Score = 76.6 bits (180), Expect = 7e-13
Identities = 35/72 (48%), Positives = 51/72 (70%), Gaps = 1/72 (1%)
Frame = +2
Query: 314 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA-DSVITA 490
E+ L+ Y ++ ++RR E G LY +I GFCHLY GQEAVAVG++AA++ DSVIT
Sbjct: 37 EELLEFYRRMLMIRRFEERCGQLYGLGLIAGFCHLYIGQEAVAVGLQAALQPGRDSVITG 96
Query: 491 YRCHGWLISWAL 526
YR HG ++++ +
Sbjct: 97 YREHGHMLAYGI 108
>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=62; Bacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 348
Score = 113 bits (272), Expect = 5e-24
Identities = 50/83 (60%), Positives = 69/83 (83%), Gaps = 2/83 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G+S GV++ELTGRR G S+GKGGSMH++ + +FYGG+GIVGAQV LG G+AFA++YR
Sbjct: 103 GMSARGVMAELTGRRGGLSKGKGGSMHMFSKEKHFYGGHGIVGAQVSLGTGLAFANRYRG 162
Query: 694 DGGVTFALYGDGAANQGQLFEAY 762
+ V+ A +GDGAANQGQ++E++
Sbjct: 163 NDNVSLAYFGDGAANQGQVYESF 185
Score = 85.8 bits (203), Expect = 1e-15
Identities = 42/97 (43%), Positives = 56/97 (57%)
Frame = +2
Query: 248 RNQPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG 427
R K K D T A + ED LK Y ++ ++RR E +G LY I GFCHLY G
Sbjct: 12 RKTAAKPAKKDFAGGTIAEFSKEDDLKAYREMLLIRRFEEKAGQLYGMGFIGGFCHLYIG 71
Query: 428 QEAVAVGMRAAMRDADSVITAYRCHGWLISWALVCWG 538
QEAV VGM+ A+++ D VIT YR HG +++ + G
Sbjct: 72 QEAVVVGMQLALKEGDQVITGYRDHGHMLACGMSARG 108
>UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10102,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 491
Score = 112 bits (270), Expect = 8e-24
Identities = 74/193 (38%), Positives = 94/193 (48%), Gaps = 23/193 (11%)
Frame = +2
Query: 254 QPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQE 433
Q LH+L++GP A LT E L+ Y + +RR+E + LYK+KIIRGFCHLY GQE
Sbjct: 1 QKCDLHRLEEGPPEKAELTREQGLQYYRTMQTIRRMELKADQLYKQKIIRGFCHLYDGQE 60
Query: 434 AVAVGMRAAMRDADSVITAYRCHGWL----ISWALVCWGCSRS*RGAGP----------- 568
A A G+ AA+ +D +ITAYR HG+ +S + + G P
Sbjct: 61 ACAAGIEAAITPSDHLITAYRAHGYTFTRGVSVKEILAELTGETGGTFPSSLVPQRLHRS 120
Query: 569 ----VAPG----AREVPCICTDATSMVATGLLVRRFRWEPEWPSPTSTAPTGESRSLCTE 724
VA G A+ C CT S AT RF WE E P ST T S CT
Sbjct: 121 LPPQVAEGAWPKAKGALCTCTRLISTEATASWELRFLWELELLWPASTRETSSCVSRCTA 180
Query: 725 TEPPIRVNSSKPT 763
T PIR + P+
Sbjct: 181 TAQPIRASCLSPS 193
>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
Intramacronucleata|Rep: Pyruvate dehydrogenase E1
component - Tetrahymena thermophila SB210
Length = 429
Score = 109 bits (261), Expect = 1e-22
Identities = 55/105 (52%), Positives = 72/105 (68%), Gaps = 5/105 (4%)
Frame = +1
Query: 460 DARCRLSDHRVSLSRM---AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYG 624
+A C L D ++ R AY G + +++EL GR+TG + GKGGSMH Y + +FYG
Sbjct: 140 EAACNLEDAIITAYRCHCHAYTRGDTPHQIIAELMGRKTGSTGGKGGSMHFYRKKTHFYG 199
Query: 625 GNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G+GIVGAQVP+GAG+AFA KY V+ +YGDGAANQGQ+ EA
Sbjct: 200 GHGIVGAQVPMGAGLAFALKYEKKPNVSITMYGDGAANQGQIAEA 244
Score = 90.2 bits (214), Expect = 5e-17
Identities = 39/70 (55%), Positives = 51/70 (72%)
Frame = +2
Query: 293 TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 472
T +T T E+ LKLY+ + ++R+IE A LYK++ IRGFCHLY GQEAV G+ AA
Sbjct: 87 TQSTATKEELLKLYKDMNVMRKIELACDKLYKQREIRGFCHLYDGQEAVISGIEAACNLE 146
Query: 473 DSVITAYRCH 502
D++ITAYRCH
Sbjct: 147 DAIITAYRCH 156
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 109 bits (261), Expect = 1e-22
Identities = 49/83 (59%), Positives = 61/83 (73%)
Frame = +1
Query: 514 LMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
+ G SV ++ EL GRR G GKGGS+H++ +NF+GGNGIVG+ VPLG G+AFA +Y
Sbjct: 138 MRGGSVKSIIGELLGRRDGICHGKGGSVHMFTKNFFGGNGIVGSNVPLGTGIAFAQQYDD 197
Query: 694 DGGVTFALYGDGAANQGQLFEAY 762
VT LYGDGAANQGQ+ EAY
Sbjct: 198 TKKVTVNLYGDGAANQGQVHEAY 220
Score = 83.0 bits (196), Expect = 8e-15
Identities = 40/90 (44%), Positives = 58/90 (64%)
Frame = +2
Query: 245 IRNQPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYS 424
I + ++ + LD P + T T +LY ++++RR+E A+ LYKE+ IRGFCHL +
Sbjct: 49 IADDSFETYNLDPPPYSLET-TKSQLKQLYYDMSLIRRMELAADKLYKEQKIRGFCHLST 107
Query: 425 GQEAVAVGMRAAMRDADSVITAYRCHGWLI 514
GQEAVAVG+ + D VITAYR HG+ +
Sbjct: 108 GQEAVAVGVEHGISPEDKVITAYRAHGFTL 137
>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
Encephalitozoon cuniculi
Length = 349
Score = 108 bits (260), Expect = 1e-22
Identities = 49/92 (53%), Positives = 71/92 (77%), Gaps = 6/92 (6%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHK 684
+AY+ G S+L ++ E+ GR+ G +GKGGSMHLY ++F+GG+GIVGAQ+PLG G+A+A +
Sbjct: 100 IAYVTGCSILEIMGEVLGRQAGVCKGKGGSMHLYNKSFFGGHGIVGAQIPLGLGMAYALE 159
Query: 685 YR-----ADGG-VTFALYGDGAANQGQLFEAY 762
Y + GG V +A YGDGAANQGQ++E++
Sbjct: 160 YNRRMGWSQGGKVCYAFYGDGAANQGQVWESF 191
Score = 60.1 bits (139), Expect = 6e-08
Identities = 27/64 (42%), Positives = 40/64 (62%)
Frame = +2
Query: 314 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 493
+ A+ +Y+Q+ +R ++ A YK K IRGFCHL GQE + + AM D D +++Y
Sbjct: 37 DKAVYIYKQMMRMRCMDEAMDREYKRKNIRGFCHLSIGQEGIYAALEYAM-DGDVAVSSY 95
Query: 494 RCHG 505
RCHG
Sbjct: 96 RCHG 99
>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=1; Aspergillus fumigatus|Rep:
Pyruvate dehydrogenase E1 component alpha subunit,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 360
Score = 108 bits (259), Expect = 2e-22
Identities = 46/84 (54%), Positives = 62/84 (73%)
Frame = +1
Query: 511 YLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYR 690
++ G S++ ++ EL GR+ G S GKGGSMH++ F+GGNGIVGA VP+GAG+AFA +Y
Sbjct: 134 FMRGGSIMSIVGELLGRQDGISHGKGGSMHMFCAGFFGGNGIVGAHVPVGAGIAFAQQYN 193
Query: 691 ADGGVTFALYGDGAANQGQLFEAY 762
+T YGDGAANQGQ+ EA+
Sbjct: 194 DRDNITVDAYGDGAANQGQVHEAF 217
Score = 66.9 bits (156), Expect = 5e-10
Identities = 30/52 (57%), Positives = 39/52 (75%)
Frame = +2
Query: 353 RRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 508
+R+E A+ LYK+K IRGFCHL +GQEAVAVG+ + D +ITAYR HG+
Sbjct: 81 QRLEIAADALYKQKKIRGFCHLSTGQEAVAVGIEYGISKEDKLITAYRSHGF 132
>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Euplotes sp. BB-2004
Length = 389
Score = 104 bits (249), Expect = 3e-21
Identities = 54/105 (51%), Positives = 68/105 (64%), Gaps = 5/105 (4%)
Frame = +1
Query: 460 DARCRLSDHRVSLSR---MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLY--GRNFYG 624
+A + DH ++ R A G + +++E+ R TG S+GKGGSMH Y NFYG
Sbjct: 99 EAALTMEDHIINAYRDHTTAMGRGHTSYEIIAEMMQRSTGSSKGKGGSMHYYCSKNNFYG 158
Query: 625 GNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
GNGIVGAQVP+G GVAF KY V A+YGDGAANQGQ++EA
Sbjct: 159 GNGIVGAQVPVGTGVAFGIKYEGKKEVCVAMYGDGAANQGQIYEA 203
Score = 87.0 bits (206), Expect = 5e-16
Identities = 38/82 (46%), Positives = 54/82 (65%), Gaps = 1/82 (1%)
Frame = +2
Query: 260 YKLHKLDQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 436
+K+H++++ T AT T + L Y+ + ++RR+E S LYK K IRGFCHLY GQE+
Sbjct: 34 FKVHRIEESELPTKATTTKSELLNYYKDMALMRRVEIVSDMLYKNKWIRGFCHLYDGQES 93
Query: 437 VAVGMRAAMRDADSVITAYRCH 502
+ VGM AA+ D +I AYR H
Sbjct: 94 ITVGMEAALTMEDHIINAYRDH 115
>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
(Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 369
Score = 102 bits (244), Expect = 1e-20
Identities = 44/81 (54%), Positives = 57/81 (70%)
Frame = +2
Query: 266 LHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 445
+H+L++GP T A LT E L+ Y + +RR+E S LYK+KIIRGFCHLY GQEA V
Sbjct: 53 VHRLEEGPPTQAVLTREQGLQYYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCV 112
Query: 446 GMRAAMRDADSVITAYRCHGW 508
G+ AA+ D +ITAYR HG+
Sbjct: 113 GLEAAINPTDHLITAYRAHGY 133
Score = 82.6 bits (195), Expect = 1e-14
Identities = 38/66 (57%), Positives = 49/66 (74%), Gaps = 3/66 (4%)
Frame = +1
Query: 460 DARCRLSDHRVSLSRM---AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGN 630
+A +DH ++ R +Y GVSV +L+ELTGRR GC++GKGGSMH+Y +NFYGGN
Sbjct: 115 EAAINPTDHLITAYRAHGYSYTRGVSVKEILAELTGRRGGCAKGKGGSMHMYAKNFYGGN 174
Query: 631 GIVGAQ 648
GIVGAQ
Sbjct: 175 GIVGAQ 180
>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 334
Score = 100 bits (240), Expect = 4e-20
Identities = 46/83 (55%), Positives = 63/83 (75%), Gaps = 2/83 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQVPLGAGVAFAHKYRA 693
G++ GV++ELTGR G S GKGGSMH++ R FYGG+GIVGAQV LG G+AFA+KYR
Sbjct: 88 GMTPRGVMAELTGRSGGYSHGKGGSMHMFSREKEFYGGHGIVGAQVALGTGLAFANKYRG 147
Query: 694 DGGVTFALYGDGAANQGQLFEAY 762
V+ +G+GA+ QGQ++E++
Sbjct: 148 TDEVSIVYFGEGASAQGQVYESF 170
Score = 70.1 bits (164), Expect = 6e-11
Identities = 32/77 (41%), Positives = 45/77 (58%)
Frame = +2
Query: 284 GPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 463
G + L+ E + Y + ++RR E +G LY +I GFCHLY GQEAV VG+ M
Sbjct: 9 GRSNGPALSPETMKRAYRDMLLVRRFEEKAGQLYGMGLIGGFCHLYIGQEAVVVGIGLNM 68
Query: 464 RDADSVITAYRCHGWLI 514
+ D IT+YR HG ++
Sbjct: 69 KQGDKSITSYRDHGQML 85
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 100 bits (239), Expect = 5e-20
Identities = 45/87 (51%), Positives = 61/87 (70%), Gaps = 2/87 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQVPLGAGVAFAH 681
A +G+ +++EL G+ TGCS+GKGGSMH + +N++GG+GIVG Q+PLG G+A+A
Sbjct: 99 AIAVGMDTKALMAELYGKATGCSKGKGGSMHYFDPSKNYWGGHGIVGGQIPLGTGLAYAV 158
Query: 682 KYRADGGVTFALYGDGAANQGQLFEAY 762
KYR G A GDGA NQG + EAY
Sbjct: 159 KYRGLKGSAMAFMGDGAVNQGAVHEAY 185
Score = 67.3 bits (157), Expect = 4e-10
Identities = 36/74 (48%), Positives = 45/74 (60%)
Frame = +2
Query: 296 SATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDAD 475
+A LT ++LY + +RR E S Y+ K I GF HLY GQEAVAVG + M + D
Sbjct: 28 NADLTPAARIELYRTMVRIRRFEERSLRAYQAKKIGGFLHLYIGQEAVAVGCCSLMGEHD 87
Query: 476 SVITAYRCHGWLIS 517
VITAYR HG I+
Sbjct: 88 HVITAYRDHGHAIA 101
>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Salinibacter
ruber (strain DSM 13855)
Length = 470
Score = 95.9 bits (228), Expect = 1e-18
Identities = 44/87 (50%), Positives = 58/87 (66%), Gaps = 2/87 (2%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFA 678
M MG++ ++EL G+ TGCS+GKGGSMH + + GG+ IVGA +PLGAG+AFA
Sbjct: 213 MGLAMGITPEAGMAELFGKETGCSKGKGGSMHFFDAEKKMMGGHAIVGAHLPLGAGLAFA 272
Query: 679 HKYRADGGVTFALYGDGAANQGQLFEA 759
HKYR + V +GDGA +QG EA
Sbjct: 273 HKYRGEDNVCLCFFGDGAMHQGAFREA 299
Score = 56.8 bits (131), Expect = 6e-07
Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 YKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 439
Y+ + D + ++ L L + + RR E +Y+ + I GF HLY GQEAV
Sbjct: 130 YETYPADTYGHDELGIADDEVLDLLRNMLLQRRFENRCRQMYQRQKISGFLHLYIGQEAV 189
Query: 440 AVG-MRAAMRDADSVITAYRCHG 505
+ G + A DSVITAYR HG
Sbjct: 190 STGSVNAIELGDDSVITAYRDHG 212
>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
alpha subunit - Trypanosoma cruzi
Length = 378
Score = 93.5 bits (222), Expect = 5e-18
Identities = 47/79 (59%), Positives = 57/79 (72%), Gaps = 5/79 (6%)
Frame = +1
Query: 538 VLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVA--FAHKYR-ADGG 702
V +E+ G+ GCS+GKGGSMH+Y NF+GGNGIVGAQVP+GAG+ FA + R
Sbjct: 120 VFAEMFGKEGGCSKGKGGSMHMYSVKNNFFGGNGIVGAQVPIGAGLGWRFALENRDKPRN 179
Query: 703 VTFALYGDGAANQGQLFEA 759
V YGDGAANQGQ+FEA
Sbjct: 180 VAVTFYGDGAANQGQVFEA 198
Score = 77.8 bits (183), Expect = 3e-13
Identities = 41/91 (45%), Positives = 53/91 (58%), Gaps = 4/91 (4%)
Frame = +2
Query: 254 QPYKLHKL---DQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLY 421
+P+KLH D P T+AT +E K E + +RR+E+ YK K IRGFCHLY
Sbjct: 21 KPFKLHTAGRDDVPPVPTTATYDTEQMKKCLEMMFRIRRMESLCDQSYKLKKIRGFCHLY 80
Query: 422 SGQEAVAVGMRAAMRDADSVITAYRCHGWLI 514
GQEA+ VGM + D ++TAYR H W I
Sbjct: 81 IGQEAIPVGMENVLTLEDLIVTAYRDHAWYI 111
>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
dehydrogenase E1 component alpha subunit, putative -
Leishmania major
Length = 378
Score = 90.6 bits (215), Expect = 4e-17
Identities = 46/79 (58%), Positives = 58/79 (73%), Gaps = 5/79 (6%)
Frame = +1
Query: 538 VLSELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQVPLGAGVA--FAHKYR-ADGG 702
V +E+ GR+ GCS+GKGGSMH+Y FYGGNGIVGAQV +GAG+A FA + R +
Sbjct: 120 VFAEMFGRQGGCSKGKGGSMHMYRVDNGFYGGNGIVGAQVSIGAGLAWRFAMENRDSPKH 179
Query: 703 VTFALYGDGAANQGQLFEA 759
V YGDGAANQGQ++E+
Sbjct: 180 VAVTFYGDGAANQGQIYES 198
Score = 74.5 bits (175), Expect = 3e-12
Identities = 39/92 (42%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Frame = +2
Query: 254 QPYKLH---KLDQGPATSATLTSEDALKLYEQLTI-LRRIETASGNLYKEKIIRGFCHLY 421
+P+KLH + D P + + + LK L +RR+E+ YK K IRGFCHLY
Sbjct: 21 RPFKLHTAGRTDMAPLPTQAVYDAEQLKQSLALMFRIRRMESLCDQSYKLKKIRGFCHLY 80
Query: 422 SGQEAVAVGMRAAMRDADSVITAYRCHGWLIS 517
GQEA+ GM + D +IT YR HGW IS
Sbjct: 81 IGQEAIPAGMENVLTFEDPIITGYRDHGWYIS 112
>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Antonospora locustae (Nosema locustae)
Length = 342
Score = 89.8 bits (213), Expect = 7e-17
Identities = 45/95 (47%), Positives = 59/95 (62%), Gaps = 9/95 (9%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHK 684
+A + V ++ EL GR G ++GKGGSMHLY +GG+GIVGAQVPLG G+A+A K
Sbjct: 90 LAVAAEIPVREIVGELLGRAGGVAKGKGGSMHLYNDLLFGGHGIVGAQVPLGCGMAYALK 149
Query: 685 YR---------ADGGVTFALYGDGAANQGQLFEAY 762
Y V F YGDGA+NQGQ+ E++
Sbjct: 150 YNEGLEDVRDTTSKAVVFCFYGDGASNQGQIHESF 184
Score = 53.2 bits (122), Expect = 7e-06
Identities = 25/74 (33%), Positives = 40/74 (54%)
Frame = +2
Query: 296 SATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDAD 475
S + +D KLY ++ +R ++ + +Y +IRGFCHL GQE V + R+ D
Sbjct: 21 SCKIRYDDVEKLYRKMLCMRYMDESISKMYSRGLIRGFCHLDIGQEEVYAALCHVARN-D 79
Query: 476 SVITAYRCHGWLIS 517
I +YRCH ++
Sbjct: 80 KFIGSYRCHALAVA 93
>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
Dehydrogenase complex, E1 component, alpha subunit -
Lentisphaera araneosa HTCC2155
Length = 320
Score = 89.4 bits (212), Expect = 9e-17
Identities = 40/82 (48%), Positives = 56/82 (68%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G++ V++E+ G+ TGC RGKGGSMH++ + N+ GG+GIVG Q+P+G G AFA KY
Sbjct: 76 GLTSREVMAEMFGKITGCVRGKGGSMHVFSKKNNYLGGHGIVGGQIPIGLGAAFALKYEE 135
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
GV +GDGA+ QG E+
Sbjct: 136 KEGVALTFFGDGASMQGTFHES 157
Score = 69.7 bits (163), Expect = 8e-11
Identities = 31/63 (49%), Positives = 41/63 (65%)
Frame = +2
Query: 314 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 493
E AL++ EQ+ +RR E Y++K I GFCH Y GQEAVAVG A + D+ +T+Y
Sbjct: 7 EKALQMLEQMIRVRRFEEGCLKSYQQKFITGFCHTYIGQEAVAVGAMAHLTPTDAYVTSY 66
Query: 494 RCH 502
RCH
Sbjct: 67 RCH 69
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 88.2 bits (209), Expect = 2e-16
Identities = 41/86 (47%), Positives = 57/86 (66%), Gaps = 2/86 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAH 681
A L G+++ G+++E+ G+R GCSRG+GGSMHL+ R FYGGN IVG +PL AG+A A
Sbjct: 84 ALLRGLAMNGIMAEMYGKREGCSRGRGGSMHLFDRATRFYGGNAIVGGGLPLAAGLALAD 143
Query: 682 KYRADGGVTFALYGDGAANQGQLFEA 759
K +T +G+GA +G EA
Sbjct: 144 KMAGRQALTACFFGEGAIAEGAFHEA 169
Score = 59.7 bits (138), Expect = 8e-08
Identities = 29/62 (46%), Positives = 39/62 (62%)
Frame = +2
Query: 320 ALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 499
AL + + +RR+E LY E+ IRGF HLY G+EAVAVG A++ D+V+ YR
Sbjct: 21 ALAVLAGMLRIRRMEEKCAQLYGEQKIRGFLHLYIGEEAVAVGALRALQPQDNVVATYRE 80
Query: 500 HG 505
HG
Sbjct: 81 HG 82
>UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=1; Magnetospirillum magneticum AMB-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 647
Score = 86.6 bits (205), Expect = 6e-16
Identities = 43/95 (45%), Positives = 58/95 (61%)
Frame = +1
Query: 475 LSDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVP 654
LS+HR +A+ V G+++E+ GR +G RG+GGS HL G+ F+ NGI+G P
Sbjct: 63 LSNHRGHGHYLAWTDDVE--GLIAEVMGRESGVCRGRGGSQHLRGQGFFS-NGIIGGMAP 119
Query: 655 LGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
+ AG+A AH+ DGGV GDG QG LFEA
Sbjct: 120 VAAGLAMAHRLAGDGGVAVLFIGDGGLGQGALFEA 154
Score = 42.3 bits (95), Expect = 0.013
Identities = 19/59 (32%), Positives = 33/59 (55%)
Frame = +2
Query: 344 TILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWLISW 520
T++R +E +LY E + G H GQE V + +A+R D +++ +R HG ++W
Sbjct: 17 TLIRVVEERLLSLYGEGRLHGTVHTCIGQEWTGVSVASALRSGDYILSNHRGHGHYLAW 75
>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 353
Score = 85.4 bits (202), Expect = 1e-15
Identities = 42/86 (48%), Positives = 53/86 (61%), Gaps = 2/86 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAH 681
A L+G V++EL G+RTG +GKGGSMHL+ R F GG GIVG +PLG G+A+A
Sbjct: 91 ALLLGCDPKEVMAELFGKRTGLVKGKGGSMHLFDVERGFMGGYGIVGGHIPLGVGIAYAL 150
Query: 682 KYRADGGVTFALYGDGAANQGQLFEA 759
+Y G+ GDGA N G EA
Sbjct: 151 RYGGSEGICQLYLGDGAINNGAFHEA 176
Score = 62.1 bits (144), Expect = 2e-08
Identities = 31/70 (44%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
Frame = +2
Query: 296 SATLTSEDAL-KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 472
SA TS D L +LY ++ ++R E A +++ I G+ H+Y+GQEAVA G A R+
Sbjct: 19 SAVATSPDRLAELYGKMVLIRAFEDACQRAFRQGKIGGYLHVYTGQEAVATGFLEAFREG 78
Query: 473 DSVITAYRCH 502
D VIT YR H
Sbjct: 79 DRVITGYRDH 88
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 85.0 bits (201), Expect = 2e-15
Identities = 45/104 (43%), Positives = 61/104 (58%), Gaps = 5/104 (4%)
Frame = +1
Query: 463 ARCRLSDHRVSLSR---MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGG 627
A R D+ +S R A + G V++EL G+ TG +GKGGSMHL+ + F GG
Sbjct: 59 AALRKDDYILSAYREHAQAIVRGAEPRRVMAELFGKATGMCKGKGGSMHLFDPSLAFMGG 118
Query: 628 NGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
IVG Q P+ G+AFA KYR +G ++ +GDGA NQG E+
Sbjct: 119 YAIVGGQFPIAVGLAFASKYRKEGRISACFFGDGAVNQGTFHES 162
Score = 67.3 bits (157), Expect = 4e-10
Identities = 33/72 (45%), Positives = 44/72 (61%)
Frame = +2
Query: 299 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 478
A L + LK++EQ+ + R E + Y + I GF HLYSGQEAVAVG AA+R D
Sbjct: 7 AILPDSELLKMHEQMVLSREFEESCAEQYTKGHITGFLHLYSGQEAVAVGATAALRKDDY 66
Query: 479 VITAYRCHGWLI 514
+++AYR H I
Sbjct: 67 ILSAYREHAQAI 78
>UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8;
Chlamydiaceae|Rep: Pyruvate Dehydrogenase Alpha -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 342
Score = 84.2 bits (199), Expect = 3e-15
Identities = 40/85 (47%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHK 684
+A L+ + + + +EL G+ TGC+ G+GGSMH+ G NF GG GIVG Q+PL AG AF K
Sbjct: 93 LAILLNIPLQEIAAELLGKETGCALGRGGSMHMCGPNFPGGFGIVGGQIPLAAGAAFTIK 152
Query: 685 YRAD-GGVTFALYGDGAANQGQLFE 756
Y+ V+ GDGA QG E
Sbjct: 153 YQEQKNRVSLCFIGDGAVAQGVFHE 177
Score = 47.6 bits (108), Expect = 4e-04
Identities = 23/64 (35%), Positives = 33/64 (51%)
Frame = +2
Query: 323 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
+K +Q+ ++R E Y E ++ GF H Y+GQEAVA A V ++YRCH
Sbjct: 32 IKFLKQMVLIREFEARGEEAYLEGLVGGFYHSYAGQEAVATAAIANTGLDPWVFSSYRCH 91
Query: 503 GWLI 514
I
Sbjct: 92 ALAI 95
>UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=1; Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E1
alpha subunit - Nyctotherus ovalis
Length = 136
Score = 83.4 bits (197), Expect = 6e-15
Identities = 39/92 (42%), Positives = 56/92 (60%), Gaps = 1/92 (1%)
Frame = +2
Query: 242 DIRNQPYKLHKLDQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 418
+I+ Y++ LD+ T A ++ LK Y + RR+E +YK+K +RGFCHL
Sbjct: 23 EIKLPQYEVFNLDKSILPTKAQTNRDEMLKYYHDMNFQRRVEIMCDEIYKKKEVRGFCHL 82
Query: 419 YSGQEAVAVGMRAAMRDADSVITAYRCHGWLI 514
GQEAV+VG+ A + D +ITAYRCHG L+
Sbjct: 83 MDGQEAVSVGVEAGITKEDHLITAYRCHGVLL 114
>UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, alpha subunit; n=2; unclassified
Epsilonproteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E1 component, alpha subunit -
Nitratiruptor sp. (strain SB155-2)
Length = 323
Score = 81.8 bits (193), Expect = 2e-14
Identities = 38/87 (43%), Positives = 55/87 (63%), Gaps = 2/87 (2%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFA 678
+A G+ V++EL G+ TG S+GKGGSMHL+ +FYGG+ IV +P+ G A+A
Sbjct: 67 LAIARGMDPKVVMAELFGKVTGISKGKGGSMHLFDPRLSFYGGDAIVAGHLPIATGCAYA 126
Query: 679 HKYRADGGVTFALYGDGAANQGQLFEA 759
K + FA++GDGA+N G FE+
Sbjct: 127 RKIEGENAGVFAIFGDGASNAGAFFES 153
Score = 36.7 bits (81), Expect = 0.67
Identities = 23/57 (40%), Positives = 28/57 (49%)
Frame = +2
Query: 332 YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
Y + + R E A+ Y + I GF HL GQEA +VG A D V T YR H
Sbjct: 10 YYLMKLGREFEIAAKQEYMKGNIAGFLHLDIGQEACSVGSMQAF-DKGDVFTHYREH 65
>UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1;
Prochlorococcus marinus subsp. pastoris str.
CCMP1986|Rep: Dehydrogenase, E1 component -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 324
Score = 79.8 bits (188), Expect = 7e-14
Identities = 35/88 (39%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G ++ ++ EL G+ +GC+ GKGGSMH+ N +G NGIVG VP+ G+A A+K
Sbjct: 98 GGNISMLIDELHGKESGCNGGKGGSMHVADLSINHFGANGIVGGGVPIACGIALANKLDK 157
Query: 694 DGGVTFALYGDGAANQGQLFEAYTCLNY 777
+ F +GDGA+NQG + E++ +
Sbjct: 158 KDSIVFCFFGDGASNQGVVLESFNLAGF 185
Score = 43.2 bits (97), Expect = 0.008
Identities = 21/56 (37%), Positives = 34/56 (60%)
Frame = +2
Query: 350 LRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWLIS 517
+R IE A +L K+ +RG H Y G+EA+A G+ + + D+V + +R HG I+
Sbjct: 41 IRAIEEAIVSLAKDNKLRGPIHSYVGEEAIATGVLSHAKPIDAVTSTHRGHGHYIA 96
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 78.6 bits (185), Expect = 2e-13
Identities = 36/86 (41%), Positives = 52/86 (60%), Gaps = 2/86 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQVPLGAGVAFAH 681
A G+ + +++EL G+ TGCS+G GGSMH +NF+GG IVG+ +PL GVA
Sbjct: 89 AIARGLDINALMAELFGKVTGCSKGLGGSMHFADASKNFWGGYAIVGSHLPLATGVALGM 148
Query: 682 KYRADGGVTFALYGDGAANQGQLFEA 759
K + V +GDGA N G+ +E+
Sbjct: 149 KMQRKDSVVMVFFGDGATNGGEFYES 174
Score = 60.1 bits (139), Expect = 6e-08
Identities = 30/74 (40%), Positives = 40/74 (54%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
L + + Y Q+ ++RR E +Y I GF HLY G+EA AVG AA+R D +
Sbjct: 21 LDAATLIDYYRQMVLIRRFEEKCQEMYTRAKIGGFLHLYIGEEATAVGAIAALRPDDHIF 80
Query: 485 TAYRCHGWLISWAL 526
T YR HG I+ L
Sbjct: 81 THYRDHGHAIARGL 94
>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
(Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 345
Score = 76.2 bits (179), Expect = 9e-13
Identities = 42/107 (39%), Positives = 59/107 (55%), Gaps = 1/107 (0%)
Frame = +1
Query: 439 GSRYESSDARCRLSDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNF 618
G+ Y+ D +S HR +A GV + G+ +E+ G+ TG +GKGG MHL+ ++
Sbjct: 77 GTLYDIRDEDVVVSTHRPHHHAIA--KGVDLKGLAAEILGKATGLCKGKGGHMHLFDKSK 134
Query: 619 -YGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
+ +GIVGA P AG AFA KY V + G+GAAN G E
Sbjct: 135 NFACSGIVGASFPQAAGAAFAFKYLGKDNVAISFAGEGAANHGTFAE 181
Score = 46.0 bits (104), Expect = 0.001
Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 9/78 (11%)
Frame = +2
Query: 296 SATLTSEDALKLYEQLTILRRIETASGNLYKEKI---------IRGFCHLYSGQEAVAVG 448
+A L + D L +Y+++ I+R E + +Y E IRG HL GQEAVAVG
Sbjct: 18 NAGLKASDLLNMYKRMLIIRYFEESIRKIYHEGKNPFNMASGRIRGEMHLSIGQEAVAVG 77
Query: 449 MRAAMRDADSVITAYRCH 502
+RD D V++ +R H
Sbjct: 78 TLYDIRDEDVVVSTHRPH 95
>UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; Rhodopseudomonas palustris HaA2|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
Rhodopseudomonas palustris (strain HaA2)
Length = 323
Score = 75.4 bits (177), Expect = 2e-12
Identities = 43/109 (39%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
Frame = +1
Query: 439 GSRYESSDARCRLSDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN- 615
G+ E +D +S HR +A G S+ +++E+ GR TGCSRGKGGSMHL +
Sbjct: 49 GAALEPADLA--VSGHRAHAHYLA--KGGSLKAMIAEIYGRVTGCSRGKGGSMHLIDESA 104
Query: 616 -FYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
F G IVG VP+G G+A+ K + G + GD G FEA
Sbjct: 105 GFMGSTAIVGGTVPVGVGLAYPMKLKRTGQIACVFLGDAVPETGVFFEA 153
Score = 38.7 bits (86), Expect = 0.17
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +2
Query: 311 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 490
SE +L + +R +E Y E+ +R HL GQEAVA AA+ AD ++
Sbjct: 2 SELPRRLLFDMMRIRAVEETIAKRYGEQKMRCPTHLSVGQEAVAAAAGAALEPADLAVSG 61
Query: 491 YRCH 502
+R H
Sbjct: 62 HRAH 65
>UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase
(Lipoamide), E1 component, alpha chain; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Putative pyruvate
dehydrogenase (Lipoamide), E1 component, alpha chain -
Protochlamydia amoebophila (strain UWE25)
Length = 342
Score = 74.1 bits (174), Expect = 4e-12
Identities = 37/86 (43%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHK 684
+A L+G + +++EL GR TG ++G+GGSMH + GG GIV QVP+ G AFA K
Sbjct: 88 LALLLGATPNELMAELYGRATGNAKGRGGSMHFFTDRLLGGFGIVTGQVPIATGAAFALK 147
Query: 685 YRAD-GGVTFALYGDGAANQGQLFEA 759
Y+ + V GDGA QG E+
Sbjct: 148 YKGNKNEVAVCFMGDGAVPQGSFHES 173
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = +2
Query: 323 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
++ ++Q+ +R E + + Y++ I GF H Y GQEA+ A+ ++ T+YRCH
Sbjct: 27 IECFQQMLKIRNFELRAESAYQQGKIGGFFHAYVGQEAIQTAAVQAIGQSNWYATSYRCH 86
>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 339
Score = 74.1 bits (174), Expect = 4e-12
Identities = 36/81 (44%), Positives = 49/81 (60%), Gaps = 2/81 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQVPLGAGVAFAHKYRA 693
G V++EL G+ TG SRG+GGSMH++ + F GG +VG PL AG+A A K++
Sbjct: 78 GAPAREVMAELYGKETGSSRGRGGSMHIFDPSVRFMGGYALVGQPFPLAAGLALACKHQK 137
Query: 694 DGGVTFALYGDGAANQGQLFE 756
+G + GDGA NQG E
Sbjct: 138 EGRIAVCFLGDGANNQGTFHE 158
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/67 (44%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
Frame = +2
Query: 317 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG---MRAAMRDA--DSV 481
D +L ++ RR E S Y E+ + GF HLYSGQEAVA G M A R D
Sbjct: 5 DRKRLLREMVFFRRFEDRSFEAYMERKVGGFLHLYSGQEAVATGVLEMVQADRGVGFDYA 64
Query: 482 ITAYRCH 502
IT YR H
Sbjct: 65 ITGYRDH 71
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 74.1 bits (174), Expect = 4e-12
Identities = 40/92 (43%), Positives = 53/92 (57%), Gaps = 12/92 (13%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYR- 690
GV V V++EL G+ TGCSRG+GGSMH++ + N GG +G Q+P+ G AF+ YR
Sbjct: 325 GVPVREVMAELFGKATGCSRGRGGSMHMFSKKHNMIGGFAFIGEQIPVALGYAFSAAYRR 384
Query: 691 ------ADGG---VTFALYGDGAANQGQLFEA 759
+D V GDG N GQL+EA
Sbjct: 385 FAMGDKSDSNADQVAVCFLGDGTTNMGQLYEA 416
Score = 49.2 bits (112), Expect = 1e-04
Identities = 24/58 (41%), Positives = 33/58 (56%)
Frame = +2
Query: 329 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
L E + R +E A LY GF HLY+GQEAV+ G+ +R D+V++ YR H
Sbjct: 261 LLEDMLTGRMVEDACARLYYMGKTAGFVHLYTGQEAVSAGVIKLLRPDDAVVSTYRDH 318
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 73.7 bits (173), Expect = 5e-12
Identities = 37/82 (45%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G + + +EL GR TG G GGSMH+ + R G NGIVGA + LG G A A + A
Sbjct: 90 GADLGRMFAELMGRETGYCAGLGGSMHIADFDRGILGANGIVGAGIGLGTGAALAEQLDA 149
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
G + + +GDGAAN+G EA
Sbjct: 150 TGAIGISFFGDGAANEGIFHEA 171
Score = 51.2 bits (117), Expect = 3e-05
Identities = 26/76 (34%), Positives = 41/76 (53%)
Frame = +2
Query: 290 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 469
AT L +D + + +RR ET + L+ + +I+G H GQEA+A G A +
Sbjct: 13 ATPNGLAPKDLRAALKMMLRIRRFETRAKELFLQGVIKGTAHSSVGQEAIAAGACAVLEP 72
Query: 470 ADSVITAYRCHGWLIS 517
AD ++T +R HG I+
Sbjct: 73 ADFILTHHRGHGHTIA 88
>UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridium
cellulolyticum H10|Rep: Pyruvate dehydrogenase -
Clostridium cellulolyticum H10
Length = 321
Score = 73.7 bits (173), Expect = 5e-12
Identities = 35/82 (42%), Positives = 50/82 (60%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G + +++EL R+TGC+ G+GGSMHL R +G IVG +PLG G A A K +
Sbjct: 73 GGDIKQMIAELYLRKTGCTSGRGGSMHLMAADRGIFGSTAIVGGSLPLGTGTALASKIQK 132
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
+ VT +GDGAA++G E+
Sbjct: 133 NDRVTAVFFGDGAADEGTFHES 154
Score = 36.7 bits (81), Expect = 0.67
Identities = 20/71 (28%), Positives = 35/71 (49%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
+ +E ++LY + +R +E YK ++ HL GQEA+A G+ +R D +
Sbjct: 1 MENERFIELYRVMQTIRIVERKIEEEYKNDEMKTPIHLSIGQEAIAAGVCINLRKDDYLF 60
Query: 485 TAYRCHGWLIS 517
+R H I+
Sbjct: 61 GTHRSHAQYIA 71
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 73.3 bits (172), Expect = 6e-12
Identities = 40/94 (42%), Positives = 51/94 (54%), Gaps = 9/94 (9%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAHKYR- 690
GV V++EL G+ TGCS+G+GGSMH++ NF GG + +P+ G AF YR
Sbjct: 93 GVPSKNVMAELFGKETGCSKGRGGSMHIFSAPHNFLGGFAFIAEGIPVATGAAFQSIYRQ 152
Query: 691 ------ADGGVTFALYGDGAANQGQLFEAYTCLN 774
D VT +GDG N GQ FE CLN
Sbjct: 153 QVLKETEDLRVTACFFGDGTTNNGQFFE---CLN 183
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/71 (35%), Positives = 37/71 (52%)
Frame = +2
Query: 290 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 469
+T L + L LYE + + R E +Y + + GF HLY+GQEAV+ G+ +
Sbjct: 16 STGLNLNKSNLLVLYEDMLLGRNFEDMCAQMYYKGKMFGFVHLYNGQEAVSTGVIKLLNP 75
Query: 470 ADSVITAYRCH 502
D V + YR H
Sbjct: 76 TDYVCSTYRDH 86
>UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2;
Bacteria|Rep: Dehydrogenase, E1 component - Comamonas
testosteroni KF-1
Length = 327
Score = 72.9 bits (171), Expect = 8e-12
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQVPLGAGVAFAH 681
A+ GV +L+EL R TG G+GGS + F+G N IVGA P+ G A A
Sbjct: 79 AHACGVPAEAILAELLARETGVCAGRGGSAYFSAPEWGFFGENSIVGAGAPIACGAALAS 138
Query: 682 KYRADGGVTFALYGDGAANQGQLFEAYTCLNY 777
DG + +GDGA NQG +FEA +Y
Sbjct: 139 TMAKDGSLAITAFGDGAMNQGGVFEAMNFASY 170
Score = 49.6 bits (113), Expect = 9e-05
Identities = 26/63 (41%), Positives = 35/63 (55%)
Frame = +2
Query: 320 ALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 499
A +L EQ+ +R +E +L K I+G HL GQEA+ G AA + D V + YR
Sbjct: 16 AKELLEQMIRIRLLEEKIADLRKSGEIQGSVHLCIGQEAIYSGSCAARQPGDRVFSTYRG 75
Query: 500 HGW 508
HGW
Sbjct: 76 HGW 78
>UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha; n=58; cellular
organisms|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha - Ralstonia eutropha
(strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 333
Score = 72.1 bits (169), Expect = 1e-11
Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
GV + ++ E+ G++ G GKGGSMH+ + G NGI+GA PL G A A K+R
Sbjct: 86 GVDPVAMMKEIYGKKGGSCNGKGGSMHIADLSKGMMGANGILGAGAPLICGAALAAKFRG 145
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
G V GDGA+NQG E+
Sbjct: 146 KGEVGITFCGDGASNQGTFLES 167
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/71 (32%), Positives = 36/71 (50%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
L E L +Y ++ +R E + I GF HLY+G+EA VG+ + D D +
Sbjct: 14 LDKETLLTVYRKMRTIRDFEERLHVDFGRGDIPGFVHLYAGEEAAGVGILHHLNDGDRIA 73
Query: 485 TAYRCHGWLIS 517
+ +R HG I+
Sbjct: 74 STHRGHGHCIA 84
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 70.5 bits (165), Expect = 4e-11
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G+ + G+++EL G+ TG S+G+GGSMHL + +G NGIVG L G A +Y
Sbjct: 91 GIDINGMMAELAGKATGTSKGRGGSMHLANVEKGNFGSNGIVGGGYALAVGAALTQQYLG 150
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
+ A GD A N+G E+
Sbjct: 151 TDNIVIAFSGDSATNEGSFHES 172
Score = 44.8 bits (101), Expect = 0.003
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = +2
Query: 302 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 481
++T E L ++ ++ +R ++ L + ++G H G+EA AVG A + D D +
Sbjct: 18 SITKEQHLDMFLKMQQIRDVDMKLNKLVRRGFVQGMTHFSVGEEAAAVGPIAGLTDEDII 77
Query: 482 ITAYRCHGWLIS 517
+ +R HG +I+
Sbjct: 78 FSHHRGHGHVIA 89
>UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha
subunit; n=1; Burkholderia xenovorans LB400|Rep:
Putative 2-oxo acid dehydrogenase alpha subunit -
Burkholderia xenovorans (strain LB400)
Length = 334
Score = 70.1 bits (164), Expect = 6e-11
Identities = 36/81 (44%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G+ V G E+ GR G +G+GGSMH+ G NGIVGA +P+ G A AH R
Sbjct: 86 GIDVGGFFKEIMGRVGGLCKGRGGSMHVADLALGVLGANGIVGAGIPIALGSAVAHHVRK 145
Query: 694 DGGVTFALYGDGAANQGQLFE 756
GV A +GDGA +G L E
Sbjct: 146 TRGVAVAFFGDGAMAEGVLHE 166
Score = 49.2 bits (112), Expect = 1e-04
Identities = 19/65 (29%), Positives = 39/65 (60%)
Frame = +2
Query: 323 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
+ +Y + ++R +E + L+ + + GF HL GQEAV+ G+ + + D++ T +R H
Sbjct: 20 IDIYRTMVLVREVELSLSRLFADSEVPGFIHLSLGQEAVSAGVASVLEVQDTLATTHRGH 79
Query: 503 GWLIS 517
G +++
Sbjct: 80 GHVLA 84
>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
component alpha-subunit, putative; n=22; Bacteria|Rep:
Pyruvate dehydrogenase, TPP-dependent E1 component
alpha-subunit, putative - Streptococcus sanguinis
(strain SK36)
Length = 357
Score = 70.1 bits (164), Expect = 6e-11
Identities = 35/87 (40%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G + G+++E+ G+ TG +GKGGSMH+ + G NG+VG L G A +KY
Sbjct: 111 GGDLKGMMAEIFGKETGLGKGKGGSMHIADLDKGILGANGMVGGGFGLATGAAMRNKYLK 170
Query: 694 DGGVTFALYGDGAANQGQLFEAYTCLN 774
V +GDGAAN+G E CLN
Sbjct: 171 TDSVAVCFFGDGAANEGNFHE---CLN 194
Score = 49.2 bits (112), Expect = 1e-04
Identities = 22/71 (30%), Positives = 40/71 (56%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
++ E A +Y+ + +R E + + I GF HLY+G+EA+A G+ A + D D +
Sbjct: 39 VSKEKAKTMYKTMWDIRNFEENTRRFFAAGQIPGFVHLYAGEEAIATGVCANLTDKDYIT 98
Query: 485 TAYRCHGWLIS 517
+ +R HG ++
Sbjct: 99 STHRGHGHCVA 109
>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
Pyruvate dehydrogenase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 332
Score = 69.7 bits (163), Expect = 8e-11
Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G V +++EL G+ G RGKGGSMH + G NGIVG +P+ G A+ +
Sbjct: 74 GADVSRMMAELLGKEAGYCRGKGGSMHTVDFSLGIMGTNGIVGGGIPIAVGSAWGDRQLG 133
Query: 694 DGGVTFALYGDGAANQGQLFE 756
VT + +GDGA+NQG FE
Sbjct: 134 RDTVTVSFFGDGASNQGVFFE 154
Score = 53.2 bits (122), Expect = 7e-06
Identities = 26/71 (36%), Positives = 41/71 (57%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
L E + + + +RR E L+K + GF HLY G+EAVAVG +A+R+ D +
Sbjct: 2 LGEEKLVGMLRLMLRIRRFEEKLAELFKRGKLPGFVHLYIGEEAVAVGACSALREDDRIT 61
Query: 485 TAYRCHGWLIS 517
+ +R HG +I+
Sbjct: 62 STHRGHGHVIA 72
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 68.5 bits (160), Expect = 2e-10
Identities = 31/76 (40%), Positives = 45/76 (59%)
Frame = +1
Query: 529 VLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVT 708
V G+++E+ G+ TG G+GGS HL F+ NGI G +P+ G AFA K R D ++
Sbjct: 72 VTGLIAEVMGKETGVCGGRGGSQHLCKEGFFS-NGIQGGILPVATGAAFAKKLRHDNSIS 130
Query: 709 FALYGDGAANQGQLFE 756
A GDG +G ++E
Sbjct: 131 IAFIGDGTLGEGVVYE 146
>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
pacifica SIR-1
Length = 339
Score = 68.5 bits (160), Expect = 2e-10
Identities = 37/88 (42%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAH 681
A G ++EL G+ TG G GGSMH + R +GG I+G VP+ AG AFA
Sbjct: 85 ALAQGSDANACMAELFGKATGLVGGVGGSMHYFDRPNGLWGGYAIIGNHVPVAAGHAFAS 144
Query: 682 KYRADGGVTFALYGDGAANQGQLFEAYT 765
KY D VT GDGA G E T
Sbjct: 145 KYLGDDAVTMCFLGDGAVGIGPTHEGMT 172
Score = 65.3 bits (152), Expect = 2e-09
Identities = 29/77 (37%), Positives = 45/77 (58%)
Frame = +2
Query: 287 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 466
P T + ++ LK + ++ +RR E + Y I GF HLY GQEA+AVG++ AM+
Sbjct: 11 PETLTSAGKDETLKAFREMLRIRRFEETAARAYTRGKISGFLHLYIGQEAIAVGVKLAMQ 70
Query: 467 DADSVITAYRCHGWLIS 517
D V+ YR HG+ ++
Sbjct: 71 ANDRVVGTYRDHGYALA 87
>UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 331
Score = 68.1 bits (159), Expect = 2e-10
Identities = 33/81 (40%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G + +++EL G+ TG +GKGGSMHL + G IVG+ VP+ AG A K +
Sbjct: 76 GAKLRPLMAELLGKATGICKGKGGSMHLSDFSVGSLGETSIVGSGVPVAAGAALGSKLQG 135
Query: 694 DGGVTFALYGDGAANQGQLFE 756
+G V +GDGA N+G E
Sbjct: 136 NGRVALCFFGDGATNEGAFHE 156
Score = 43.6 bits (98), Expect = 0.006
Identities = 20/65 (30%), Positives = 37/65 (56%)
Frame = +2
Query: 311 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 490
++ +L+ Y ++ +R+ E + ++ + I G H Y+GQEA VG A+ D D ++
Sbjct: 6 NDRSLEKYRRMQRIRQFEDLAEAIHAQGEIPGSLHTYAGQEASGVGACMALDDTDYMVGT 65
Query: 491 YRCHG 505
+R HG
Sbjct: 66 HRSHG 70
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 67.7 bits (158), Expect = 3e-10
Identities = 35/82 (42%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G S+ GV+ EL GR G GKGGSMHL G IVGA +P+ G A++ K R
Sbjct: 90 GASMTGVMGELMGRSVGLMAGKGGSMHLTSVEHGMMGSYAIVGAHLPVAVGAAWSAKVRG 149
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
V +GDG N G EA
Sbjct: 150 TNQVVVCFFGDGTTNIGAFHEA 171
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/81 (34%), Positives = 42/81 (51%)
Frame = +2
Query: 275 LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 454
L + P +A + + L L+E + LR E + +L+ + +++G HL GQEAVA G
Sbjct: 9 LPERPTFTAEVNGRE-LDLFELMVRLRFFERRAHDLFLQGLVKGTSHLSLGQEAVATGFA 67
Query: 455 AAMRDADSVITAYRCHGWLIS 517
AAM D YR H +S
Sbjct: 68 AAMEPTDLTFATYRGHAHTLS 88
>UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit; n=2; Clostridium
difficile|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit - Clostridium difficile
(strain 630)
Length = 322
Score = 67.3 bits (157), Expect = 4e-10
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +1
Query: 517 MGVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAHKYR 690
MG+ + +++EL G+ TG +GKGGSMH+ G NG+VG + + G A +Y+
Sbjct: 76 MGIDLNKMMAELMGKETGFCKGKGGSMHIADIESGNLGANGVVGGGLTIAPGAALTQQYK 135
Query: 691 ADGGVTFALYGDGAANQGQLFE 756
G + +GDGA+N+G E
Sbjct: 136 KTGKIVLCSFGDGASNEGTFHE 157
>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) alpha chain - Rhizobium loti
(Mesorhizobium loti)
Length = 342
Score = 66.9 bits (156), Expect = 5e-10
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G V + +E G+ TG +G+GGSMH+ + G NGIVG +P+ G A + K
Sbjct: 94 GAEVKRMFAEFFGKTTGYCKGRGGSMHIADVAKGNLGANGIVGGGIPIAVGAALSSKMMK 153
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
G V + +GDGA N+G EA
Sbjct: 154 TGKVVVSFFGDGANNEGAFHEA 175
Score = 41.9 bits (94), Expect = 0.018
Identities = 20/70 (28%), Positives = 38/70 (54%)
Frame = +2
Query: 308 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVIT 487
++E ++ ++ ++RR E + Y +I G HL GQEA A+G+ + + D + +
Sbjct: 23 SAEQLREVLYKMYLIRRFEEGAEESYMRGLIHGTMHLSIGQEASAMGICMPLGEDDQITS 82
Query: 488 AYRCHGWLIS 517
+R HG I+
Sbjct: 83 THRGHGHCIA 92
>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
component - Chloroflexus aurantiacus J-10-fl
Length = 334
Score = 66.9 bits (156), Expect = 5e-10
Identities = 33/82 (40%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G V +++E G+ TG RG+GGSMH+ N G NGIVG +P+ GV + K R
Sbjct: 94 GSDVRLMMAEFLGKETGYCRGRGGSMHIANVEMNNLGANGIVGGGIPISVGVGLSIKKRR 153
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
V ++GDGA N G E+
Sbjct: 154 SSQVCLTIFGDGAVNTGAFHES 175
Score = 51.2 bits (117), Expect = 3e-05
Identities = 22/61 (36%), Positives = 36/61 (59%)
Frame = +2
Query: 338 QLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWLIS 517
++ I+R E + L+ ++ G HL GQEAVA+G AAM+ D ++ +R HG ++
Sbjct: 33 RMQIIRAFEEKAEELFARGLVHGTMHLSIGQEAVAIGASAAMKPGDYLLNHHRGHGHCLA 92
Query: 518 W 520
W
Sbjct: 93 W 93
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 66.9 bits (156), Expect = 5e-10
Identities = 33/82 (40%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G +++E G+RTG ++GK G++H+ N +VG +P+ AGVAFA KYR
Sbjct: 76 GADPNALMAECFGKRTGFNKGKSGTLHVAVPEVNALCTTTVVGGGIPIAAGVAFAQKYRK 135
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
VT +GDGAA++G EA
Sbjct: 136 QKNVTVCFFGDGAADEGSFHEA 157
Score = 42.3 bits (95), Expect = 0.013
Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +2
Query: 308 TSEDALKLYEQLTILRRIETASGNLYK-EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
T E L++ + + RR E L + E + G L +GQEAVA G+ AA+ D ++
Sbjct: 4 TKEKLLEMLRSMLLTRRFEEKLTELCQIEGKVPGMMILCTGQEAVAAGVCAALEPQDVIV 63
Query: 485 TAYRCHGWLIS 517
+R HG L++
Sbjct: 64 PNHRSHGHLLA 74
>UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 347
Score = 65.7 bits (153), Expect = 1e-09
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 517 MGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQVPLGAGVAFAHKYR 690
+G+ + SE+ + +G S+G GGSMHL+G + F G IVG VPL G A A K +
Sbjct: 94 LGIDLKSFFSEILAKSSGISKGMGGSMHLFGGSVGFCGSVPIVGGTVPLAVGTALASKLK 153
Query: 691 ADGGVTFALYGDGAANQGQLFEAYTCLNYGTC 786
+ V+ + GDGA +G + E+ C
Sbjct: 154 EEKVVSISYLGDGAIEEGIVHESLNFARINNC 185
Score = 37.5 bits (83), Expect = 0.38
Identities = 18/68 (26%), Positives = 36/68 (52%)
Frame = +2
Query: 314 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 493
++ L++ ++ ++R E + ++ G HL GQEA+ VG+ + + D V A+
Sbjct: 26 DELLEMLSKMILIRNAEYKIAKGREFGLVGGPVHLGVGQEAIPVGISQYLNNQDKVFGAH 85
Query: 494 RCHGWLIS 517
R H ++S
Sbjct: 86 RSHSHILS 93
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 65.3 bits (152), Expect = 2e-09
Identities = 33/74 (44%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
Frame = +1
Query: 541 LSELTGRRTGCSRGKGGSMHLYGRNF--YGGNGIVGAQVPLGAGVAFAHKYRADGGVTFA 714
L+E+ G G RG+GGSMHL G N IVG VP+ AG A+AH+ G V +
Sbjct: 125 LAEILGLSQGFCRGRGGSMHLRWAESGNLGTNAIVGGGVPMAAGAAWAHRRAGKGDVVYT 184
Query: 715 LYGDGAANQGQLFE 756
+GDGA N G + E
Sbjct: 185 YFGDGATNIGSVLE 198
Score = 36.3 bits (80), Expect = 0.88
Identities = 19/66 (28%), Positives = 33/66 (50%)
Frame = +2
Query: 329 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 508
+ Q+ ++R E L + ++ G H GQE AVG +MR +D + ++R H
Sbjct: 34 MLSQMHLIRAFEEKVLELAGQGLVHGPAHSAIGQEGGAVGSAVSMRPSDQINGSHRAHHQ 93
Query: 509 LISWAL 526
++ AL
Sbjct: 94 FLAKAL 99
>UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 327
Score = 65.3 bits (152), Expect = 2e-09
Identities = 34/74 (45%), Positives = 44/74 (59%), Gaps = 2/74 (2%)
Frame = +1
Query: 544 SELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFAL 717
+E+ GR TG +GKGG MHL + GIVG+ P+ G+A+A K G VT A
Sbjct: 87 AEIAGRVTGACKGKGGPMHLTYPAKGIMVTTGIVGSTAPIANGLAWAAKLEGKGRVTIAN 146
Query: 718 YGDGAANQGQLFEA 759
+GDGAAN G + EA
Sbjct: 147 FGDGAANIGAVHEA 160
>UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3;
Actinomycetales|Rep: Dehydrogenase, E1 component -
Salinispora tropica CNB-440
Length = 323
Score = 64.9 bits (151), Expect = 2e-09
Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G +++EL GR TG +RG+GGSMH + G N IVGA + G +A + R
Sbjct: 73 GADPARMMAELCGRVTGLNRGRGGSMHAADFAVGVLGANAIVGAGGAIVTGAVWARRRRG 132
Query: 694 DGGVTFALYGDGAANQGQLFEAY 762
D V + GDGA N+G L EA+
Sbjct: 133 DDLVGVSFLGDGAVNEGMLLEAF 155
Score = 48.0 bits (109), Expect = 3e-04
Identities = 24/71 (33%), Positives = 40/71 (56%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
+T +++LY + ++RR E + L + I G H Y GQE +A G+ AA+R D V
Sbjct: 1 MTEVGSVRLYRTVRLIRRFEERAIELVRSGHIVGGIHPYVGQEGIAAGVCAALRPDDVVA 60
Query: 485 TAYRCHGWLIS 517
+R HG +++
Sbjct: 61 GTHRGHGHVLA 71
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 63.7 bits (148), Expect = 5e-09
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 529 VLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVT 708
V G+++E+ G+ G G GGS HL+ NF+ NGI G VP+ AG A A+ + + ++
Sbjct: 83 VYGLIAEIMGKDDGVCGGVGGSQHLHTENFFS-NGIQGGMVPVAAGRALANALQGNNAIS 141
Query: 709 FALYGDGAANQGQLFEAY 762
GDG +G ++E +
Sbjct: 142 VVFIGDGTLGEGVIYETF 159
Score = 37.5 bits (83), Expect = 0.38
Identities = 19/68 (27%), Positives = 34/68 (50%)
Frame = +2
Query: 314 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 493
+D +L +R++E L+ E ++ G H GQE V + A++ D+V + +
Sbjct: 11 KDCYELTVTALTIRKVEERLLELFSEGVLNGTIHTCIGQEWTGVAVANALQAGDTVFSNH 70
Query: 494 RCHGWLIS 517
R HG I+
Sbjct: 71 RGHGHYIA 78
>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
Length = 331
Score = 63.3 bits (147), Expect = 7e-09
Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Frame = +1
Query: 478 SDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQV 651
S HR +A G + +++EL G+ TGC G+GGSMHL F G IVG+ +
Sbjct: 71 SSHRAHSHYLA--KGGDLKAMIAELYGKSTGCCGGRGGSMHLIDLAAGFIGATPIVGSTI 128
Query: 652 PLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
P+ G A++ R VT +GDG +G + E+
Sbjct: 129 PIAVGHAWSAYLRGKNRVTVVFFGDGCFEEGVMHES 164
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/63 (38%), Positives = 38/63 (60%)
Frame = +2
Query: 314 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 493
E+ L Y L ++RR+E A Y E+ +R HL GQEAVAVG+ ++ +D + +++
Sbjct: 14 EELLTFYRSLLLIRRVEEAIAERYTEQEMRCPTHLCIGQEAVAVGVCKMLQQSDGIFSSH 73
Query: 494 RCH 502
R H
Sbjct: 74 RAH 76
>UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2;
Alphaproteobacteria|Rep: Dehydrogenase E1 component -
Sinorhizobium medicae WSM419
Length = 342
Score = 61.7 bits (143), Expect = 2e-08
Identities = 29/76 (38%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Frame = +1
Query: 538 VLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTF 711
+++E+ G+ TG RGKGGSMH+ G N IVG +P G + ++ V+
Sbjct: 83 MMAEIGGKETGYCRGKGGSMHIADMALGHLGANAIVGGGIPAVIGAGLSSRHLKQDSVSI 142
Query: 712 ALYGDGAANQGQLFEA 759
A +GDGA QG L+E+
Sbjct: 143 AFFGDGAMQQGILYES 158
Score = 37.9 bits (84), Expect = 0.29
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Frame = +2
Query: 323 LKLYEQLTILRRIETASGNLYKEKIIRG-FCHLYSGQEAVAVGMRAAMRDADSVITAYRC 499
L+LY + +R E G L+ G HL G+E+ A G+ AAM+ D+ T +R
Sbjct: 10 LELYRTMRRIRTFEERVGELFVRGQSAGSMLHLSIGEESSAAGVCAAMKPQDTFTTHHRG 69
Query: 500 HG 505
HG
Sbjct: 70 HG 71
>UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable pyruvate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 344
Score = 60.9 bits (141), Expect = 4e-08
Identities = 37/104 (35%), Positives = 56/104 (53%), Gaps = 5/104 (4%)
Frame = +1
Query: 463 ARCRLSDHRVSL--SRMAYL-MGVSVLGVLSELTGRRTGCSRGKGGSMHL-YG-RNFYGG 627
A R +DH V SR++ L G++ + E+ GR T SRG+ G H+ Y YG
Sbjct: 74 ALMRETDHLVPYHRSRVSILGKGMTARDLAMEIMGRATAPSRGRAGETHINYAPARIYGT 133
Query: 628 NGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G++GA +P+ AGVA+ + R V +G+G +N+G EA
Sbjct: 134 TGVLGANIPIAAGVAYGVQQRGLDEVVVCGFGEGTSNRGAFHEA 177
>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
marine actinobacterium PHSC20C1
Length = 327
Score = 60.5 bits (140), Expect = 5e-08
Identities = 33/83 (39%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Frame = +1
Query: 517 MGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNF--YGGNGIVGAQVPLGAGVAFAHKYR 690
MG + E+ GR G GKGGSMHL + G N IVG +P G A A YR
Sbjct: 84 MGAPLDRAFGEILGRAGGLCGGKGGSMHLADVSVGALGSNAIVGGHLPTTVGAALAASYR 143
Query: 691 ADGGVTFALYGDGAANQGQLFEA 759
V+ A +GDG+ N G E+
Sbjct: 144 GTSEVSVAFFGDGSTNIGAFHES 166
Score = 50.8 bits (116), Expect = 4e-05
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +2
Query: 317 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYR 496
DAL+L + +R E L+ + ++RG HL GQEAV VG+ +A+ D++ YR
Sbjct: 17 DALELLRSMYEIRFFEDEIMGLFSQNLVRGSTHLCQGQEAVTVGVCSALSPGDTMTCTYR 76
Query: 497 CHGWLIS 517
HG +++
Sbjct: 77 GHGAVLA 83
>UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Sphingomonas wittichii RW1
Length = 334
Score = 60.1 bits (139), Expect = 6e-08
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQVPLGAGVAFAH 681
A G+ + G EL G+ G +G+GGSMH+ + G NGIVG V + G A
Sbjct: 86 ALAKGLGLDGFFRELMGKADGACKGRGGSMHVADLSVGMLGANGIVGGGVAIALGSGLAQ 145
Query: 682 KYRADGGVTFALYGDGAANQGQLFEA 759
K R G+ +GDGA +G + E+
Sbjct: 146 KLRGGDGLAICFFGDGALAEGIVHES 171
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/82 (31%), Positives = 46/82 (56%)
Frame = +2
Query: 281 QGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 460
+G A + + ++LY ++ +R E + G L+ I GF HL GQE V+VG+ A+
Sbjct: 10 RGAAHGRNARAPELIELYRRMVTIREAEKSCGALFAAGEIPGFIHLSDGQEGVSVGVMAS 69
Query: 461 MRDADSVITAYRCHGWLISWAL 526
+R D++ + +R HG ++ L
Sbjct: 70 LRADDTIASTHRGHGHALAKGL 91
>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
bacterium HTCC2654
Length = 335
Score = 60.1 bits (139), Expect = 6e-08
Identities = 31/83 (37%), Positives = 47/83 (56%)
Frame = +2
Query: 269 HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 448
H + A S T T ED L++Y Q+ +R E + LY + G H+YSG+EAVAVG
Sbjct: 5 HLREDTMAKSKTNT-EDYLRMYRQMVRIRTFEDNANQLYLSAKMPGLTHMYSGEEAVAVG 63
Query: 449 MRAAMRDADSVITAYRCHGWLIS 517
+ A+ D D + + +R HG ++
Sbjct: 64 ICEALTDDDRITSTHRGHGHCVA 86
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNF--YGGNGIVGAQVPLGAGVAFAHKYRA 693
G + EL G+ G RGKGGSMH+ ++ G N IVG + + G A K +
Sbjct: 88 GAEFKEMFCELLGKEEGYCRGKGGSMHIADQSHGNLGANAIVGGSMGIATGSALRAKLQG 147
Query: 694 DGGVTFALYGDGAANQGQLFE 756
VT +GDGA QG ++E
Sbjct: 148 SDDVTVCFFGDGATAQGLMYE 168
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 60.1 bits (139), Expect = 6e-08
Identities = 37/90 (41%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAH 681
A G+ V++EL GR TG S+G GGSMHL+ GG GIVG Q+P G A A
Sbjct: 104 ALARGIDPGRVMAELFGRTTGVSKGWGGSMHLFDAETRLLGGYGIVGGQIPPATGAALAI 163
Query: 682 KYRADGG----VTFALYGDGAANQGQLFEA 759
YR G L GD N G E+
Sbjct: 164 AYRQPPGPDTPAVVCLVGDATTNIGAWHES 193
Score = 56.8 bits (131), Expect = 6e-07
Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Frame = +2
Query: 248 RNQPYKLHKLDQGPATSATLTSEDALKLY-EQLTILRRIETASGNLYKEKIIRGFCHLYS 424
R P L PA D L+ Y + ++RR E + +Y+ I G+CHL
Sbjct: 16 RANPATAPDLATTPADRLAQEPPDKLRAYYRMMQLIRRFEERAAEMYQRAKIGGYCHLNL 75
Query: 425 GQEAVAVGMRAAMRDADSVITAYRCHGWLIS 517
G+EA VG+ AM D + T YR HG+ ++
Sbjct: 76 GEEATVVGLMDAMAPHDYLFTTYREHGYALA 106
>UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. EAN1pec
Length = 332
Score = 59.7 bits (138), Expect = 8e-08
Identities = 33/83 (39%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYG---GNGIVGAQVPLGAGVAFAHKYR 690
GV ++ + E+ GR+ G RGKGG+MH+ R G GIVG+ P+ G+A A + +
Sbjct: 81 GVPLVEIYGEMLGRQVGSGRGKGGTMHI-ARPDSGVMLSTGIVGSGPPVAVGMAMAARRK 139
Query: 691 ADGGVTFALYGDGAANQGQLFEA 759
VT +GDGA N G EA
Sbjct: 140 GLDRVTAVSFGDGATNTGSFHEA 162
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 59.7 bits (138), Expect = 8e-08
Identities = 33/81 (40%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Frame = +1
Query: 535 GVLSELTGRRTGCSRGKGGSMHLYGRNF--YGGNGIVGAQVPLGAGVAFAHKYRADGGVT 708
GVL+E+ GR TG +G GGSMH++ F Y N IVG + G A K G+
Sbjct: 167 GVLAEIFGRETGFQKGLGGSMHVFFPPFGIYPNNAIVGGSADIAVGAALYKKINRKKGIV 226
Query: 709 FALYGDGAANQGQLFEAYTCL 771
GDGA G ++EA CL
Sbjct: 227 IVNIGDGAMGCGPVWEA-MCL 246
Score = 37.5 bits (83), Expect = 0.38
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 7/80 (8%)
Frame = +2
Query: 308 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGF-------CHLYSGQEAVAVGMRAAMR 466
+ ED L++Y + I+R ET + G HL GQEA AVG +
Sbjct: 40 SDEDLLRIYRDMLIIREFETMLSLIKTRGEYNGIKYDYPGPAHLSIGQEAAAVGQAFILD 99
Query: 467 DADSVITAYRCHGWLISWAL 526
D + ++R HG +I+ L
Sbjct: 100 KNDFIFGSHRSHGEVIAKGL 119
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 59.7 bits (138), Expect = 8e-08
Identities = 31/79 (39%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Frame = +1
Query: 529 VLGVLSELTGRRTGCSRGKGGSMHLYG--RNFYGGNGIVGAQVPLGAGVAFAHKYRADGG 702
V SE+ G ++G G+GGSMHL G N IVG +P G A A K R +
Sbjct: 136 VFKTYSEILGLKSGYCGGRGGSMHLREPEAGVLGSNAIVGGNIPHAVGYALADKMRGERA 195
Query: 703 VTFALYGDGAANQGQLFEA 759
++ A +GDGA G +EA
Sbjct: 196 ISVAFFGDGAMQIGTAYEA 214
Score = 42.3 bits (95), Expect = 0.013
Identities = 20/59 (33%), Positives = 31/59 (52%)
Frame = +2
Query: 326 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
++ EQL ++R E L KE ++ G H GQE AVG+ +A+ D + +R H
Sbjct: 47 RMLEQLFLIRHFEERLLELSKEGLLHGPAHASIGQEGAAVGLMSALTSGDKINGTHRMH 105
>UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase alpha subunit
- Coxiella burnetii
Length = 341
Score = 58.8 bits (136), Expect = 1e-07
Identities = 32/97 (32%), Positives = 53/97 (54%), Gaps = 2/97 (2%)
Frame = +1
Query: 475 LSDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQ 648
+S HR +A G ++ +++EL G+ TG + G+GGSM+L + F IV
Sbjct: 61 VSTHRAHAHYLA--KGGNLKALIAELHGKVTGATAGRGGSMNLSDLSVGFVASTAIVANT 118
Query: 649 VPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
VP+G G+AF+ K + +T GD A +G ++E+
Sbjct: 119 VPIGVGLAFSQKLKKSNVITTIFLGDAAVEEGVVYES 155
>UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=2;
Bacteria|Rep: Acetoin dehydrogenase alpha-subunit -
consortium cosmid clone pGZ1
Length = 344
Score = 58.8 bits (136), Expect = 1e-07
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G + ++ EL GR +G GKGGSMH+ + G NG+V A +P+ G A + + +
Sbjct: 93 GADLRRMMHELFGRASGFCGGKGGSMHIADFSVGMLGANGVVAAGIPIAVGAAQSMRVQG 152
Query: 694 DGGVTFALYGDGAANQGQLFE 756
+ +GDGA N+G E
Sbjct: 153 RDSIAVCFFGDGALNRGPFGE 173
Score = 35.9 bits (79), Expect = 1.2
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +2
Query: 398 IRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWLIS 517
+RG HL +GQEAVA G+ + +R D + + +R HG I+
Sbjct: 52 VRGPLHLSTGQEAVATGVCSQLRADDWLTSTHRGHGHTIA 91
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 58.8 bits (136), Expect = 1e-07
Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQVPLGAGVAFAH 681
A G+ V++E+ R TG + G+ GS ++ + F G N IVGA + GVA A+
Sbjct: 84 ALAAGLDPEAVMAEICQRSTGLNGGRAGSAYMMAPHTRFIGENSIVGAGTTIACGVAMAN 143
Query: 682 KYRADGGVTFALYGDGAANQGQLFEA 759
+ R V GDGA NQG + EA
Sbjct: 144 RLRGRDNVVMVTIGDGAMNQGSVHEA 169
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 8/88 (9%)
Frame = +2
Query: 287 PATSATLTSEDALK------LYEQLTILRRIETASGNLYKEKIIR--GFCHLYSGQEAVA 442
P T+ T EDA K ++ ++ +R E + L + R G HL +GQE V
Sbjct: 2 PGTNPRATKEDAAKAAFLSEMFGKICFVRAFEEEALRLTQANPPRVAGSMHLCAGQEVVP 61
Query: 443 VGMRAAMRDADSVITAYRCHGWLISWAL 526
V A+ D D V+ YR HGW ++ L
Sbjct: 62 VAAMEALGDEDQVVCTYRGHGWALAAGL 89
>UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=1;
Haloferax volcanii|Rep: 2-oxo acid dehydrogenase subunit
E1 - Halobacterium volcanii (Haloferax volcanii)
Length = 353
Score = 58.8 bits (136), Expect = 1e-07
Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNF-YGGNGIVGAQVPLGAGVAFAH 681
+A GV + + +E+ GR+TG RGKGG MHL+ + + GI+ P G A A
Sbjct: 79 IAIAKGVDLKRMTAEIFGRKTGLCRGKGGHMHLFDPDVNFACAGIIAQGCPPAVGAAMAA 138
Query: 682 KYRADGGVTFALYGDGAANQGQLFEA 759
K R V A G+GA +QG E+
Sbjct: 139 KKRNTDSVAVAFLGEGAIDQGGFLES 164
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 58.0 bits (134), Expect = 3e-07
Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Frame = +1
Query: 478 SDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQV 651
SD + S M +V +++E+ G TG G+GGSMH+ G + IVG +
Sbjct: 105 SDFDILQSDFTDGMHDAVYRLMAEIMGLNTGYCGGRGGSMHMRDAASGIAGTSAIVGGNI 164
Query: 652 PLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
P AG A A K G++ A +GDG + QG +EA
Sbjct: 165 PHAAGYALADKILNRKGISVAFFGDGPSLQGATYEA 200
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/62 (33%), Positives = 32/62 (51%)
Frame = +2
Query: 317 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYR 496
D LK Y Q+ ++RR E + K ++ G H GQEA AVG + ++ D + +R
Sbjct: 30 DLLKWYSQMKLIRRFEEKILDFEKAGLVHGPAHASIGQEAAAVGAMSVLKTDDQINGTHR 89
Query: 497 CH 502
H
Sbjct: 90 TH 91
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 55.6 bits (128), Expect = 1e-06
Identities = 25/70 (35%), Positives = 40/70 (57%)
Frame = +2
Query: 293 TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 472
+ ++ E+ LYE + + R E LY K + GF HLY+GQEAV+ G+ ++++
Sbjct: 184 SDVNISREEICTLYEDMYLGRLFENLVAKLYYNKRVNGFVHLYNGQEAVSTGIIKNLKNS 243
Query: 473 DSVITAYRCH 502
D V + YR H
Sbjct: 244 DFVTSTYRDH 253
Score = 54.8 bits (126), Expect(2) = 3e-07
Identities = 26/60 (43%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCS-RGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYR 690
GV +L+EL G G + +GKGGSMH+Y + NF GG G +G Q+P+ G+A++ Y+
Sbjct: 260 GVPAHKILNELYGNYYGSTNKGKGGSMHIYSKENNFIGGFGFIGEQIPIAVGLAYSILYK 319
Score = 22.6 bits (46), Expect(2) = 3e-07
Identities = 9/19 (47%), Positives = 10/19 (52%)
Frame = +1
Query: 703 VTFALYGDGAANQGQLFEA 759
V GDG N GQ FE+
Sbjct: 358 VVVCFLGDGTTNIGQFFES 376
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 56.8 bits (131), Expect = 6e-07
Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Frame = +1
Query: 511 YLMGVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHK 684
++ GVS VL++ GR G +RG+ G+MH+ N + A VP+ G A A +
Sbjct: 91 FIRGVSARRVLAQYMGRLGGLTRGRDGNMHMGDMSVNVVSIISALAATVPVATGAALAMR 150
Query: 685 YRADGGVTFALYGDGAANQGQLFE 756
Y+ GV F+ +GDG+ ++G E
Sbjct: 151 YKGIPGVAFSYFGDGSTSRGDWHE 174
>UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 668
Score = 56.4 bits (130), Expect = 8e-07
Identities = 33/94 (35%), Positives = 48/94 (51%)
Frame = +1
Query: 478 SDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 657
S+HR +AY G V +++E+ GR TG G+GGS H+ +FY NGI G V
Sbjct: 74 SNHRCHGHYIAY--GAPVDQLIAEVMGRVTGVVGGRGGSQHICYNDFY-TNGIQGGIVGN 130
Query: 658 GAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G A A+K + GDG +G ++E+
Sbjct: 131 ATGAALANKLTGTDNIAVVFIGDGTLGEGLVYES 164
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/72 (30%), Positives = 40/72 (55%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
L+ E +Y+++ +R +E +L+ + + G H GQEA AV A +++ D V
Sbjct: 14 LSQETIDSMYKKMITIRTLEETLLDLFSKGELFGTTHTSIGQEANAVASMAHIKNGDVVF 73
Query: 485 TAYRCHGWLISW 520
+ +RCHG I++
Sbjct: 74 SNHRCHGHYIAY 85
>UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12;
Bacteria|Rep: Pyruvate dehydrogenase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 344
Score = 56.4 bits (130), Expect = 8e-07
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN-FYGGNGIVGAQVPLGAGVAFAHKYRAD 696
GV + + +E+ GR G RG+GG MHL+ + + +GI+ P G AFA +
Sbjct: 103 GVDLRRMTAEIFGREDGLGRGRGGHMHLFDPDTHFSCSGIIAEGYPPALGQAFAFHRQGT 162
Query: 697 GGVTFALYGDGAANQGQLFEA 759
+ A+ G+GAANQG E+
Sbjct: 163 DRIAVAVTGEGAANQGAFHES 183
>UniRef50_Q0ET31 Cluster: Dehydrogenase, E1 component; n=1;
Thermoanaerobacter ethanolicus X514|Rep: Dehydrogenase,
E1 component - Thermoanaerobacter ethanolicus X514
Length = 262
Score = 55.6 bits (128), Expect = 1e-06
Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN-FYGGNGIVGAQVPLGAGVAFAHK 684
A GV + + +E+ G+ TG RGKGG MHL+ + + +GIVGA +P G A K
Sbjct: 81 AIAKGVDLKRMTAEIFGKVTGLGRGKGGHMHLFDPDVHFSCSGIVGASIPQAVGAALTFK 140
Query: 685 YRADGGVTFALYGD 726
R + V A +G+
Sbjct: 141 MRKEKRVAVAFFGE 154
Score = 33.5 bits (73), Expect = 6.2
Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKI----------IRGFCHLYSGQEAVAVGMR 454
+ E +++Y ++ +R E Y+E + G HL +GQE VAVG+
Sbjct: 3 IPKETLIRMYLEMVTIRLYEETMAEAYQEGKYPVFNIASGPVPGEMHLAAGQEPVAVGVC 62
Query: 455 AAMRDADSVITAYRCHGWLIS 517
++ D+V+ +R H + I+
Sbjct: 63 MHLKKEDAVVGTHRPHHFAIA 83
>UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase
alpha-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase alpha-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 326
Score = 55.2 bits (127), Expect = 2e-06
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Frame = +1
Query: 478 SDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQV 651
S HR +A G+ + ++EL GR TGC+ G+GGS+HL F + I+G +
Sbjct: 59 SGHRCHAHYLAKGGGLGAM--VAELYGRETGCAAGRGGSVHLVDEAAGFGASSAILGEMI 116
Query: 652 PLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
+ G A+A + V +GDGA+ +G E+
Sbjct: 117 SVATGAAWAFARQEAPRVAVTFFGDGASEEGVFHES 152
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/60 (41%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Frame = +2
Query: 326 KLYEQLTILRRIETASGNLYK-EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
+L + +R IE ++Y+ E+ +R HL GQEAVAVG+ AA+R D V + +RCH
Sbjct: 5 QLLRTMVRIRCIEEEIADVYRDEQQMRTPVHLSIGQEAVAVGVCAALRTEDVVYSGHRCH 64
>UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha
subunit; n=2; Bacteria|Rep: Putative pyruvate
dehydrogenase alpha subunit - Streptomyces coelicolor
Length = 323
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/75 (34%), Positives = 38/75 (50%)
Frame = +1
Query: 535 GVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFA 714
G+L+E+ GR G GGS H+Y R+ Y G+ G +P+ GV K G +
Sbjct: 103 GLLAEIMGRAGAVCHGVGGSQHIY-RDRYLSTGVQGQSLPVAVGVGLHLKQAEPGRIAVV 161
Query: 715 LYGDGAANQGQLFEA 759
GDG +G ++EA
Sbjct: 162 HIGDGTWGEGAVYEA 176
>UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2;
Rhodocyclaceae|Rep: Dehydrogenase, E1 component -
Dechloromonas aromatica (strain RCB)
Length = 320
Score = 51.6 bits (118), Expect = 2e-05
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Frame = +1
Query: 475 LSDHRVSLSRMAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNF--YGGNGIVGAQ 648
L++HR + +A G +L+E+ GRR G +G+ GS+H+ + IVG +
Sbjct: 63 LTNHRSAGHLLA--RGADPGRMLAEVMGRRDGYCKGRSGSLHISAKELGVVLTTTIVGGE 120
Query: 649 VPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
+ L GVA A + G+ +GDGAA +G E+
Sbjct: 121 LSLAPGVALAQTMQGRPGIVACFFGDGAACEGSFHES 157
Score = 42.7 bits (96), Expect = 0.010
Identities = 27/70 (38%), Positives = 38/70 (54%)
Frame = +2
Query: 308 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVIT 487
T+ D L+LYEQL ++R E A + I G C GQEA AVG A+ D ++T
Sbjct: 6 TAVDPLRLYEQLLLIRAYENAIVRGSTDGRIPGTC-TSVGQEAAAVGAINALEADDLILT 64
Query: 488 AYRCHGWLIS 517
+R G L++
Sbjct: 65 NHRSAGHLLA 74
>UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=2; Bacteria|Rep: Pyruvate dehydrogenase E1
component, alpha subunit - Frankia alni (strain ACN14a)
Length = 342
Score = 51.2 bits (117), Expect = 3e-05
Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 8/116 (6%)
Frame = +1
Query: 436 RGSRYESSD--ARCRLSDHRVSLSRMAY---LMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
RG + ++ A R D+ V+ R + GV + + +E G+ G GKGG MH
Sbjct: 58 RGQEFAAASVAAHLRRDDYVVTTYRGLHDQIAKGVPLRELWAEYLGKAAGTCGGKGGPMH 117
Query: 601 LYGRNFYG---GNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
+ YG G+VG+ +P+ G+A + + R VT +GDGA+N G E+
Sbjct: 118 VTAPE-YGLMVTTGVVGSGLPIANGLALSAQLRGTDQVTVVNFGDGASNIGAFHES 172
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 51.2 bits (117), Expect = 3e-05
Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQVPLGAGVA--- 672
A GV V++EL G+ G RG GGSMH+Y NF GG +V Q+P G A
Sbjct: 200 AIACGVDSGAVMAELFGKDGGTCRGTGGSMHVYDMDTNFQGGWALVAEQLPYAVGAARSI 259
Query: 673 ----FAHKYRADGGVTFALYGDGAANQGQLFEAYTCLN 774
+ A +T G+G A G++ E CLN
Sbjct: 260 VLDKMLGRDDAQDRITVVFVGEGGAQNGRMAE---CLN 294
Score = 42.7 bits (96), Expect = 0.010
Identities = 23/66 (34%), Positives = 32/66 (48%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
L+ ED K Y + + R E Y IRGF HL +GQE++ + A+R D
Sbjct: 132 LSDEDLSKAYYMMQLCRDFENECNQAYMAGKIRGFMHLDNGQESIPALLNDAIRKDDLKH 191
Query: 485 TAYRCH 502
+ YR H
Sbjct: 192 SYYRDH 197
>UniRef50_A2C5U8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=1; Prochlorococcus marinus str. MIT
9303|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Prochlorococcus marinus (strain MIT 9303)
Length = 280
Score = 50.4 bits (115), Expect = 5e-05
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 3/112 (2%)
Frame = +1
Query: 448 YESSDARCRLSDHRVSLSRMAYL-MGVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNF 618
++ +D RC S HR S YL + +++EL G G +G GGSMHL
Sbjct: 38 FQKTD-RC-FSSHR---SHSMYLALACDPESLIAELHGSAFGSLQGLGGSMHLKELDSGL 92
Query: 619 YGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEAYTCLN 774
IVG+ + LG G A + K+ + +T + +GDGA +G E CLN
Sbjct: 93 EASIPIVGSSIALGVGSALSAKHSKNDVLTISYFGDGACEEGIFHE---CLN 141
>UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Candidatus Sulcia muelleri
str. Hc (Homalodisca coagulata)
Length = 58
Score = 48.8 bits (111), Expect = 2e-04
Identities = 22/54 (40%), Positives = 35/54 (64%)
Frame = +2
Query: 302 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 463
T+ ++ LK Y+ ++ R+ E +LY ++ IRGF HLY+GQEA+ G+ AM
Sbjct: 3 TINNDIYLKWYKDMSFWRKFEDKCRSLYLKQKIRGFLHLYNGQEAIPAGLVHAM 56
>UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,
alpha subunit; n=2; Deinococcus|Rep: 2-oxo acid
dehydrogenase, E1 component, alpha subunit - Deinococcus
radiodurans
Length = 381
Score = 48.0 bits (109), Expect = 3e-04
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Frame = +1
Query: 517 MGVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYR 690
+GV + ++S+ G T RG+ H R NF + + +QVP AG A A KY
Sbjct: 111 LGVPMFTLISQCLGSNTDECRGRQMPHHFSSRAHNFVSASSSIASQVPPAAGNARAQKYL 170
Query: 691 ADGGVTFALYGDGAANQG 744
+T +GDGA ++G
Sbjct: 171 GTDEITVVTFGDGATSEG 188
>UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3;
Bacteria|Rep: Dehydrogenase, E1 component - Chloroflexus
aurantiacus J-10-fl
Length = 321
Score = 48.0 bits (109), Expect = 3e-04
Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 4/88 (4%)
Frame = +1
Query: 508 AYLM-GVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVG---AQVPLGAGVAF 675
AYL+ G++ +L++ GR TG +RG+ ++H G G G + A + GVA
Sbjct: 71 AYLVRGLTPKRILAQWLGRETGVTRGRDANLHGMGDLSLGIIGFISHLPASTGVITGVAH 130
Query: 676 AHKYRADGGVTFALYGDGAANQGQLFEA 759
A K + + V +GDG+A+QG EA
Sbjct: 131 AIKLKGEPRVAMCFFGDGSASQGLAHEA 158
>UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit;
n=5; Mollicutes|Rep: Pyruvate dehydrogenase EI alpha
subunit - Mycoplasma capricolum
Length = 370
Score = 47.6 bits (108), Expect = 4e-04
Identities = 21/51 (41%), Positives = 30/51 (58%)
Frame = +1
Query: 607 GRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G N N ++G+Q G+AFA KYR GGV GDG +++G+ +EA
Sbjct: 127 GVNCLPPNIVIGSQYSQATGIAFADKYRKTGGVVVTTTGDGGSSEGETYEA 177
>UniRef50_UPI0000384B37 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Magnetospirillum
magnetotacticum MS-1|Rep: COG1071:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Magnetospirillum magnetotacticum MS-1
Length = 311
Score = 46.8 bits (106), Expect = 6e-04
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +1
Query: 526 SVLGVLSELTGRRTGCSRGKGGSMHLY--GRNFYGGNGIVGAQVPLGAGVAFAHKYRADG 699
S+ +SEL R G + G+ GSM++ GR + I+G + + AG A A G
Sbjct: 78 SLAAEVSELALRPDGLAGGRLGSMNMSNPGRGLIYTSSILGNDLCVAAGAAMAETVLGSG 137
Query: 700 GVTFALYGDGAANQGQLFEA 759
V F + GDGA +G FE+
Sbjct: 138 AVPFVVTGDGALEEGVFFES 157
>UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 325
Score = 46.0 bits (104), Expect = 0.001
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKG-GSMHLYGRNF--YGGNGIVGAQVPLGAGVAFAHKYR 690
G+ + + + G +RG G G +H+ G +G +G P+ AG A + KYR
Sbjct: 79 GMPMSKLFGDFLANTEGSTRGLGAGIVHIAWPQLGILGQSGTLGGCFPIAAGAALSAKYR 138
Query: 691 ADGGVTFALYGDGAANQGQLFEA 759
V +GDG AN+G EA
Sbjct: 139 GTDQVCLCFFGDGTANRGTFHEA 161
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 44.0 bits (99), Expect = 0.004
Identities = 19/56 (33%), Positives = 31/56 (55%)
Frame = +1
Query: 589 GSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
G++ G+N + + Q+PL AG+A A+KY+ A +GDGA ++G E
Sbjct: 116 GNLPPEGKNILPPSVPIATQLPLAAGIAMANKYKNSSQAVIAYFGDGATSEGDFHE 171
>UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7;
Mycobacterium tuberculosis complex|Rep: Dehydrogenase E1
component - Mycobacterium tuberculosis (strain ATCC
25177 / H37Ra)
Length = 334
Score = 43.2 bits (97), Expect = 0.008
Identities = 23/59 (38%), Positives = 35/59 (59%)
Frame = +2
Query: 326 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
+LY ++ +LR ++ A L E +I G GQEAV+VG AA+ + D +IT +R H
Sbjct: 18 ELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAAAALGEGDVIITTHRPH 76
>UniRef50_A5LD62 Cluster: Probable transketolase; n=1; Streptococcus
pneumoniae SP3-BS71|Rep: Probable transketolase -
Streptococcus pneumoniae SP3-BS71
Length = 270
Score = 41.9 bits (94), Expect = 0.018
Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Frame = +1
Query: 625 GNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA-YTCLN 774
G G +G +G G+A+ +K + F + GDG N+GQ++EA YTC N
Sbjct: 106 GLGSLGQGPSIGVGMAWVNKRKKSDKKIFVMLGDGELNEGQVWEAFYTCRN 156
>UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit; n=2; Thermoplasma|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit - Thermoplasma volcanium
Length = 337
Score = 41.9 bits (94), Expect = 0.018
Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Frame = +1
Query: 517 MGVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYR 690
+G + + ++ G S+G+ H + NF V +PL G A+A KYR
Sbjct: 78 LGYPIEKIFDQIMGNAEDTSKGRQMPSHYSAKAVNFMSVPSPVATNLPLAVGAAYAKKYR 137
Query: 691 ADGGVTFALYGDGAAN 738
+ G+ +GDG +
Sbjct: 138 KEDGIVITSFGDGGTS 153
>UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 665
Score = 41.5 bits (93), Expect = 0.023
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G+S++ + EL G+ T S G+ S H + N + + G Q AG A+A
Sbjct: 89 GMSIVEMTRELMGKATSHSAGRTMSNHFCSKEHNIFSVVSLTGTQCIPAAGAAWASVLDN 148
Query: 694 DGGVTFALYGDGAANQGQLFEA 759
G+ GD A QG+ +EA
Sbjct: 149 KNGLVVCGVGDAATRQGEFYEA 170
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 41.1 bits (92), Expect = 0.031
Identities = 24/74 (32%), Positives = 37/74 (50%)
Frame = +2
Query: 299 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 478
A +T E+ LY + + RR + + +L ++ + G GQEA +G A RD D
Sbjct: 63 ADITPEELRGLYRDMVLSRRFDAEATSLQRQGEL-GLWASMLGQEAAQIGSGRATRDDDY 121
Query: 479 VITAYRCHGWLISW 520
V YR HG ++W
Sbjct: 122 VFPTYREHG--VAW 133
>UniRef50_Q1IGG4 Cluster: Putative FecR-like transmembrane sensor;
n=1; Pseudomonas entomophila L48|Rep: Putative FecR-like
transmembrane sensor - Pseudomonas entomophila (strain
L48)
Length = 325
Score = 41.1 bits (92), Expect = 0.031
Identities = 24/65 (36%), Positives = 34/65 (52%)
Frame = +2
Query: 575 PGAREVPCICTDATSMVATGLLVRRFRWEPEWPSPTSTAPTGESRSLCTETEPPIRVNSS 754
P R P + + A +MV GLLV + W W + +TA TGESRS+ E I++N+
Sbjct: 85 PVRRAWPKVASAAAAMVLLGLLVGQTSWPDRWRADYATA-TGESRSIQLEDGSRIQLNTD 143
Query: 755 KPTHV 769
V
Sbjct: 144 SALQV 148
>UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=9; Mycoplasma|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Mycoplasma synoviae
Length = 374
Score = 40.7 bits (91), Expect = 0.041
Identities = 21/56 (37%), Positives = 28/56 (50%)
Frame = +1
Query: 589 GSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
GS G N N ++G Q+ AGVAFA K GGV G+G +G+ +E
Sbjct: 131 GSKIPEGVNVTPINIVIGTQISQAAGVAFALKQNKTGGVALCFIGNGGTAEGEFYE 186
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 40.7 bits (91), Expect = 0.041
Identities = 32/107 (29%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
Frame = +2
Query: 284 GPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 463
G TL + L+LY + + R ++ L ++ I GF G+EA +G AAM
Sbjct: 44 GAPDEVTLPDAEVLRLYRLMVLNRSLDERMITLQRQGRI-GFYIGSIGEEATILGSAAAM 102
Query: 464 RDADSVITAYRCHGWLI--SWALVCWGCSRS*RGAGPVAPGAREVPC 598
++D + YR HG + LV + C AG G R++PC
Sbjct: 103 AESDWIFPCYREHGAALMRGMPLVTFLCDLF-GNAGDAMKG-RQMPC 147
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 40.7 bits (91), Expect = 0.041
Identities = 22/67 (32%), Positives = 38/67 (56%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
++ E LYE + ++RRI+T + L ++ + G GQEA +G ++RD D V
Sbjct: 53 VSDEQLGSLYEDMVVIRRIDTEATALQRQGEL-GLWPPLLGQEASQIGSARSLRDDDFVF 111
Query: 485 TAYRCHG 505
++YR +G
Sbjct: 112 SSYRENG 118
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 40.3 bits (90), Expect = 0.054
Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +1
Query: 538 VLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIV---GAQVPLGAGVAFAHKYRADGGVT 708
+ ++ G+ +G ++G+ S H +G Y G++ G Q+ + G+A AHK + + +T
Sbjct: 112 LFAQWQGKASGFTKGRDRSFH-FGTQEYNIVGMISHLGPQLGVADGIALAHKLKNEKKLT 170
Query: 709 FALYGDGAANQGQLFEA 759
G+G ++G EA
Sbjct: 171 AVFSGEGGTSEGDFHEA 187
>UniRef50_Q9NYV4 Cluster: Cell division cycle 2-related protein
kinase 7; n=32; Euteleostomi|Rep: Cell division cycle
2-related protein kinase 7 - Homo sapiens (Human)
Length = 1490
Score = 40.3 bits (90), Expect = 0.054
Identities = 26/63 (41%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = -2
Query: 704 TPPSARYLWAKATPAPNGTCAP-TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPST 528
TPP + + P P T P T PLPP P +PPLP QP V + ST ST
Sbjct: 525 TPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-ST 583
Query: 527 LTP 519
L P
Sbjct: 584 LPP 586
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 39.9 bits (89), Expect = 0.072
Identities = 25/73 (34%), Positives = 33/73 (45%)
Frame = +2
Query: 287 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 466
P L E+ L L + +LRR++ A G + + G GQEA VG A R
Sbjct: 36 PEHEVDLEPEELLALLRDMVLLRRLD-AEGEALQRQGQLGLWPGSRGQEAAQVGSATACR 94
Query: 467 DADSVITAYRCHG 505
D V +YR HG
Sbjct: 95 RQDQVFPSYRDHG 107
>UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component,
alphasubunit; n=1; Mycoplasma agalactiae|Rep: Pyruvate
dehydrogenase E1 component, alphasubunit - Mycoplasma
agalactiae
Length = 363
Score = 39.9 bits (89), Expect = 0.072
Identities = 16/41 (39%), Positives = 25/41 (60%)
Frame = +1
Query: 634 IVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
++G+QVP+ AGVA A KY+ + G+G N+G+ E
Sbjct: 138 VIGSQVPIAAGVAQALKYQGKKALAMVTIGNGGTNEGEFHE 178
>UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 444
Score = 39.5 bits (88), Expect = 0.095
Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Frame = +1
Query: 580 GKGGSMHL-YGR---NFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQ 747
GKG M + YG NF + + Q+P +G A+A K + G +GDGAA++G
Sbjct: 184 GKGRQMPVHYGSKELNFVTISSTLATQMPQASGAAYALKRQGKGNCVMCYFGDGAASEG- 242
Query: 748 LFEAYTCLNYGTCL 789
+A++ N+ L
Sbjct: 243 --DAHSAFNFAATL 254
>UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Aeropyrum
pernix
Length = 377
Score = 39.5 bits (88), Expect = 0.095
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Frame = +1
Query: 583 KGGSMHLYGRNFYG---GNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQG 744
KG ++G Y VG Q+P+ G A+A KY VT +GDGA ++G
Sbjct: 123 KGSDFAIFGNRKYNLVPAPVPVGNQIPISVGAAYAMKYLGRDTVTLTFFGDGATSRG 179
>UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=10; Bacilli|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 371
Score = 38.7 bits (86), Expect = 0.17
Identities = 19/42 (45%), Positives = 23/42 (54%)
Frame = +1
Query: 634 IVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
I+GAQ AGVA K R V F GDG ++QG +EA
Sbjct: 146 IIGAQYIQAAGVALGLKKRGKENVVFTYTGDGGSSQGDFYEA 187
>UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway
signal; n=2; Proteobacteria|Rep: Twin-arginine
translocation pathway signal - Mesorhizobium sp. (strain
BNC1)
Length = 375
Score = 38.7 bits (86), Expect = 0.17
Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 4/59 (6%)
Frame = +2
Query: 326 KLYEQLTILRRIE----TASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 490
+L + T + RI T + + + RG+ H Y+GQEAVAVG+ +A+R++ V+ A
Sbjct: 30 QLVDMFTTILRIRWHERTMADKMLTDPNYRGYNHFYAGQEAVAVGVCSALRNSGGVMHA 88
Score = 36.7 bits (81), Expect = 0.67
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRN--FYGGNGIVGAQVPLGAGVAFAH 681
A GV + + +E R TG + G MHL F G +G++G + +G AFA
Sbjct: 101 AIAKGVDMKLMAAENDFRATGLNGGYAAEMHLCDPEVGFIGADGMIGPGPVIASGSAFAI 160
Query: 682 KYRADGGVTFALYGDG 729
K R V GDG
Sbjct: 161 KARGSDQVVVNFGGDG 176
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 38.3 bits (85), Expect = 0.22
Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 5/156 (3%)
Frame = +2
Query: 254 QPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQE 433
+P + LD+G L E+AL+LY + R + + L ++ + G + GQE
Sbjct: 2 KPKVVRYLDEG---EFPLAEEEALRLYRAMRRARFFDEKALTLQRQGRL-GVYAPFMGQE 57
Query: 434 AVAVGMRAAMRDADSVITAYRCHGWLISWALVCWGCSRS*RG--AGPVAP-GAREVPCIC 604
A VG+ A+ + D V+ +YR L++ L R AG P G R V
Sbjct: 58 AAQVGVALALEERDWVVPSYRESAMLLAKGLPIHTLILYWRAHPAGWRFPEGVRAVNPYI 117
Query: 605 TDATSM-VATGL-LVRRFRWEPEWPSPTSTAPTGES 706
AT + A GL L R+R E +W TS G S
Sbjct: 118 PIATQIPQAVGLALAGRYRGE-DWVVATSIGDGGTS 152
Score = 33.1 bits (72), Expect = 8.2
Identities = 13/40 (32%), Positives = 20/40 (50%)
Frame = +1
Query: 637 VGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
+ Q+P G+A A +YR + V GDG ++G E
Sbjct: 119 IATQIPQAVGLALAGRYRGEDWVVATSIGDGGTSEGDFHE 158
>UniRef50_A5ZA31 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 313
Score = 38.3 bits (85), Expect = 0.22
Identities = 20/56 (35%), Positives = 27/56 (48%)
Frame = +1
Query: 589 GSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
G+ H G F G +G + + G A A K R D G F + GDG +GQ +E
Sbjct: 144 GAEHSPG--FENTAGSLGQTISIAGGTAHARKMRGDTGKVFVMLGDGELQEGQTWE 197
>UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n=8;
Halobacteriaceae|Rep: Pyruvate dehydrogenase alpha
subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 419
Score = 38.3 bits (85), Expect = 0.22
Identities = 19/67 (28%), Positives = 37/67 (55%)
Frame = +2
Query: 305 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 484
LT ++ +++Y + + RR + + +L ++ I + L SGQE + A+ D D ++
Sbjct: 79 LTDDELVEMYRYMKLARRFDERAVSLQRQGRIGTYPPL-SGQEGAQIASAMALADDDWIV 137
Query: 485 TAYRCHG 505
+YR HG
Sbjct: 138 PSYREHG 144
>UniRef50_A1I7J5 Cluster: Putative transketolase, N-terminal
subunit; n=1; Candidatus Desulfococcus oleovorans
Hxd3|Rep: Putative transketolase, N-terminal subunit -
Candidatus Desulfococcus oleovorans Hxd3
Length = 280
Score = 37.9 bits (84), Expect = 0.29
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +1
Query: 595 MHLYGRNFYG---GNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
MHL G G G +G +P+ G+A + + +T+ + GDG N+G ++EA
Sbjct: 105 MHLDGNKVRGVDASTGSLGHGLPIAVGMALGARLQKKSWMTYCILGDGECNEGSVWEA 162
>UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep:
Zgc:158474 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 906
Score = 37.5 bits (83), Expect = 0.38
Identities = 23/63 (36%), Positives = 32/63 (50%)
Frame = -2
Query: 707 VTPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPST 528
+TPPS R + P+ + +P+ P P L P PPLP PV +P+SS S T
Sbjct: 6 LTPPSPRAAANSSPLPPSPSPSPSPPSP--SLLPLSTRPPPLPPPTPVGQPLSSLSDTPT 63
Query: 527 LTP 519
+P
Sbjct: 64 PSP 66
>UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 365
Score = 37.5 bits (83), Expect = 0.38
Identities = 17/41 (41%), Positives = 22/41 (53%)
Frame = +1
Query: 637 VGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
VG Q G+A+ KYR V A +GDGA ++G EA
Sbjct: 134 VGTQTLHAVGLAYGIKYRKGKNVAMAFFGDGATSEGDFHEA 174
>UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus cereus
Length = 371
Score = 37.5 bits (83), Expect = 0.38
Identities = 18/41 (43%), Positives = 22/41 (53%)
Frame = +1
Query: 634 IVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
I+GAQ+ AGVA K R V GDG A+QG +E
Sbjct: 146 IIGAQIIQTAGVALGMKLRGKKSVAITYTGDGGASQGDFYE 186
>UniRef50_A0LHU2 Cluster: Transketolase domain protein; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Transketolase
domain protein - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 653
Score = 37.1 bits (82), Expect = 0.50
Identities = 18/43 (41%), Positives = 24/43 (55%)
Frame = +1
Query: 631 GIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G +G + +GAG+A K R TF L GDG +GQ+ EA
Sbjct: 127 GNLGQGLSVGAGMALGLKLRGSRASTFVLMGDGEQQKGQIAEA 169
>UniRef50_Q4KXE0 Cluster: Cold acclimation induced protein 2-1; n=3;
Triticeae|Rep: Cold acclimation induced protein 2-1 -
Triticum aestivum (Wheat)
Length = 321
Score = 37.1 bits (82), Expect = 0.50
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Frame = -2
Query: 710 NVTPPSARYLWAKATPAPNGTCAPTIPLP----P*KLRPYKCMEPPLPREQPVLRPVSSE 543
++TPPSA + + +P P+ T P+P P + P P P P + P SSE
Sbjct: 176 SMTPPSAAPMPSPMSP-PSMTPPSAAPMPSPMSPPSMTPPSAAPMPSPMSPPSMAPPSSE 234
Query: 542 STPSTLTP 519
PS +TP
Sbjct: 235 PMPSPMTP 242
>UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 432
Score = 37.1 bits (82), Expect = 0.50
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHL--YGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 693
G ++ +++ G +G+ MH RNF + + Q+P G A+A K +
Sbjct: 152 GYTMENFMNQCYGNADDLGKGRQMPMHFGTKERNFVTISSPLTTQLPQAVGSAYAFKQQK 211
Query: 694 DGG-VTFALYGDGAANQGQLFEAYTCLNYGTCL 789
D + +GDGAA++G +A+ N+ L
Sbjct: 212 DNNRIAVVYFGDGAASEG---DAHAAFNFAATL 241
>UniRef50_Q97NC3 Cluster: Transketolase, N-terminal subunit; n=29;
Bacteria|Rep: Transketolase, N-terminal subunit -
Streptococcus pneumoniae
Length = 285
Score = 36.7 bits (81), Expect = 0.67
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = +1
Query: 631 GIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G +G + + G+A+ + R T+A+ GDG N+GQ +EA
Sbjct: 120 GSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCWEA 162
>UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1 alpha subunit; n=23; Bacteria|Rep:
Branched-chain alpha-keto acid dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 352
Score = 36.3 bits (80), Expect = 0.88
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Frame = +1
Query: 574 SRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQ 747
S GK H R N G+ V QV G+A A + R D V + G+G++NQG
Sbjct: 123 SGGKQMPSHWGNRPLNIVSGSSPVTTQVLHAVGIAQAARMRGDDVVVYTACGEGSSNQGD 182
Query: 748 LFEA 759
EA
Sbjct: 183 FHEA 186
>UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, E1
component, alpha subunit; n=32; Gammaproteobacteria|Rep:
Alpha keto acid dehydrogenase complex, E1 component,
alpha subunit - Idiomarina loihiensis
Length = 395
Score = 36.3 bits (80), Expect = 0.88
Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 3/88 (3%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYG---RNFYGGNGIVGAQVPLGAGVAF 675
+AY G +V +++L +G+ +H YG NF + +G Q+P G AF
Sbjct: 113 LAY-RGFTVEQFMNQLFSNEKDLGKGRQMPVH-YGCADLNFMTISSPLGTQIPQATGYAF 170
Query: 676 AHKYRADGGVTFALYGDGAANQGQLFEA 759
K T +G+GAA++G A
Sbjct: 171 GQKMDKTEKCTICYFGEGAASEGDFHAA 198
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 36.3 bits (80), Expect = 0.88
Identities = 24/100 (24%), Positives = 47/100 (47%), Gaps = 5/100 (5%)
Frame = +2
Query: 221 IQHEKRGDIRNQPYKLHKLDQGPAT-----SATLTSEDALKLYEQLTILRRIETASGNLY 385
IQ RG+ + + + ++ T +T + A + Y + +R + + +L
Sbjct: 2 IQSRDRGEEMEEQFPIKRIIDNDGTLLGDKDPGITEQLAKEFYRHMVRIRTFDKKAISLQ 61
Query: 386 KEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 505
++ I + + GQEA VG AA+++ D + +YR HG
Sbjct: 62 RQGRIGTYAP-FEGQEASQVGSSAALKEDDWMFPSYRDHG 100
>UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto
acid dehydrogenase E1; n=1; Toxoplasma gondii|Rep:
Mitochondrial branched-chain alpha-keto acid
dehydrogenase E1 - Toxoplasma gondii
Length = 463
Score = 36.3 bits (80), Expect = 0.88
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 514 LMGVSVLGVLSELTGRRTGCSRGKGG--SMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKY 687
L G + L +L RR S+G+ S + N + + QVP AG +A K
Sbjct: 180 LHGFTAEDALEQLFARRGDESKGRQMPISYSKHSVNLHTICTPLTTQVPHAAGAGYAFKL 239
Query: 688 RADGGVTFALYGDGAANQGQLFEA 759
D + A +G+GAA++G A
Sbjct: 240 AGDDRIAVAFFGEGAASEGDFHAA 263
>UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyruvate dehydrogenase -
Halorubrum lacusprofundi ATCC 49239
Length = 382
Score = 36.3 bits (80), Expect = 0.88
Identities = 23/75 (30%), Positives = 36/75 (48%)
Frame = +2
Query: 290 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 469
AT L+ E +Y L RR + + +L ++ I + +GQE AVG A+ D
Sbjct: 35 ATVPDLSDERFRAIYRDLVTTRRFDERAVSLQRQGRIGTYAPC-AGQEGSAVGSTHALAD 93
Query: 470 ADSVITAYRCHGWLI 514
D + YR HG ++
Sbjct: 94 RDLISYQYREHGAIV 108
>UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=2; Firmicutes|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Acholeplasma
laidlawii
Length = 345
Score = 36.3 bits (80), Expect = 0.88
Identities = 20/56 (35%), Positives = 27/56 (48%)
Frame = +1
Query: 589 GSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
GS+ G N I+G+Q + AG+A A K R VT GDG G+ +E
Sbjct: 102 GSIKPEGVKILPTNIIIGSQSNIAAGLAMASKIRKTNEVTAFTIGDGGTAHGEFYE 157
>UniRef50_Q89J58 Cluster: Transketolase; n=7; Bacteria|Rep:
Transketolase - Bradyrhizobium japonicum
Length = 282
Score = 35.9 bits (79), Expect = 1.2
Identities = 17/43 (39%), Positives = 25/43 (58%)
Frame = +1
Query: 631 GIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G +G + +G G+A A + R TF L GDG N+G ++EA
Sbjct: 125 GALGHGLSIGVGLALAARMRERTYRTFVLLGDGEINEGSVWEA 167
>UniRef50_A0TAK4 Cluster: Transketolase-like; n=1; Burkholderia
ambifaria MC40-6|Rep: Transketolase-like - Burkholderia
ambifaria MC40-6
Length = 268
Score = 35.9 bits (79), Expect = 1.2
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 7/112 (6%)
Frame = +1
Query: 445 RYESSDARCRLSDHRVSLSR----MAYLMGVSVLGVLS--ELTGRRTGCSRGKG-GSMHL 603
RYE S+ R D+ V LS+ MA ++ +G LS E+ +R KG H+
Sbjct: 44 RYEQSNPRSPGRDYMV-LSKGHGVMAQYACLNEIGWLSDDEIAHYFGNGTRLKGLADAHV 102
Query: 604 YGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G G+ +G + +G G+A A K +AL GDG N+G ++EA
Sbjct: 103 PGIETTAGS--LGHGLSVGVGLALAAKRNGTDQKCYALVGDGELNEGAIWEA 152
>UniRef50_Q01916 Cluster: IpiB3 protein precursor; n=3; Phytophthora
infestans|Rep: IpiB3 protein precursor - Phytophthora
infestans (Potato late blight fungus)
Length = 347
Score = 35.9 bits (79), Expect = 1.2
Identities = 33/80 (41%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +1
Query: 508 AYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKY 687
A L G G + L GR G G LYGR G G GA + G G A A Y
Sbjct: 85 AVLYGRGAGGAGAGLYGRGAGYG---GAGAGLYGRG--AGYGGAGAGLYAGYGGAGAGLY 139
Query: 688 -RADGGVTFALYGDGAANQG 744
R GGV LYG GAA G
Sbjct: 140 GRGAGGVGAGLYGRGAAYGG 159
>UniRef50_Q9V1I2 Cluster: Tkt1 transketolase N-terminal section;
n=3; Thermococcaceae|Rep: Tkt1 transketolase N-terminal
section - Pyrococcus abyssi
Length = 220
Score = 35.9 bits (79), Expect = 1.2
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +1
Query: 628 NGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE-AYTCLNYG 780
+G +G + + G+A A + G F + GDG ++GQ++E A T +YG
Sbjct: 97 SGSLGQGLSVANGIAMAKRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYG 148
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 35.5 bits (78), Expect = 1.5
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
Frame = +2
Query: 323 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC- 499
L LY ++ ++R+++ + NL + + G GQEAV +GM +AM+ D YR
Sbjct: 39 LYLYRRMALIRQLDNKAINLQRTGKM-GTYPSSRGQEAVGIGMGSAMQKEDIFCPYYRDQ 97
Query: 500 -----HGWLISWALVCWG 538
HG +S L WG
Sbjct: 98 GALFEHGIKLSEILAYWG 115
Score = 35.1 bits (77), Expect = 2.0
Identities = 15/41 (36%), Positives = 22/41 (53%)
Frame = +1
Query: 637 VGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
+ Q+ AGVA+A KYR + GDG ++G +EA
Sbjct: 138 IAGQLLHAAGVAYAVKYRKQARAVLTICGDGGTSKGDFYEA 178
>UniRef50_Q6MHR5 Cluster: InterPro: Transketolase; n=1; Bdellovibrio
bacteriovorus|Rep: InterPro: Transketolase -
Bdellovibrio bacteriovorus
Length = 677
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/61 (27%), Positives = 26/61 (42%)
Frame = +1
Query: 589 GSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEAYTC 768
G +H + + NG +G+ P GVA VT DGA +G+ EA+
Sbjct: 137 GEVHCFPEGVFISNGPLGSAFPQTQGVAMGEAISGKNRVTVTTISDGACMEGEAKEAFAA 196
Query: 769 L 771
+
Sbjct: 197 I 197
>UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Propionibacterium acnes|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit -
Propionibacterium acnes
Length = 381
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/78 (28%), Positives = 34/78 (43%)
Frame = +2
Query: 272 KLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 451
+L P L +D +K E + + RR++ + L + + G GQEA G
Sbjct: 40 RLTTHPDFPVDLVDDDLVKALEMMVMTRRLDVEATALQRHGEL-GLWPPLLGQEATQAGA 98
Query: 452 RAAMRDADSVITAYRCHG 505
A+R+ D V YR G
Sbjct: 99 WLALREGDQVFPTYREQG 116
>UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto
acid dehydrogenase, E1 alpha subunit; n=3;
Lactobacillales|Rep: TPP-dependent branched-chain
alpha-keto acid dehydrogenase, E1 alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 330
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +1
Query: 613 NFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
N + V Q+PL GV +A + + V G+G+ANQG++ EA
Sbjct: 117 NIVSFSSTVSTQMPLATGVGYAAQLQKADFVALTTTGEGSANQGEVQEA 165
>UniRef50_Q9FM99 Cluster: Similarity to carbonic anhydrase; n=1;
Arabidopsis thaliana|Rep: Similarity to carbonic
anhydrase - Arabidopsis thaliana (Mouse-ear cress)
Length = 350
Score = 35.5 bits (78), Expect = 1.5
Identities = 20/62 (32%), Positives = 27/62 (43%)
Frame = -2
Query: 704 TPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTL 525
TPP + A P P APT P P +P PP P+ +P P + + TP+
Sbjct: 49 TPPKPKPKPAPTPPKPKPAPAPTPPKP----KPAPAPTPPKPKPKPAPTPPNPKPTPAPT 104
Query: 524 TP 519
P
Sbjct: 105 PP 106
>UniRef50_A4RA81 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 471
Score = 35.1 bits (77), Expect = 2.0
Identities = 25/61 (40%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Frame = -2
Query: 701 PPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQP-VLRPVSSESTPSTL 525
P RY+ A P P T P IP P P P P E P V PV STPST+
Sbjct: 324 PSMGRYVLAGVPPLPTTTMVPRIPPPSVPPTP-----APAPVEAPGVDVPVEMPSTPSTV 378
Query: 524 T 522
T
Sbjct: 379 T 379
>UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=2; Thermus thermophilus|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 367
Score = 35.1 bits (77), Expect = 2.0
Identities = 19/85 (22%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = +1
Query: 505 MAYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGR--NFYGGNGIVGAQVPLGAGVAFA 678
+A +G+ + + ++ + ++G+ H + NF+ + + VP AG A +
Sbjct: 100 LALALGIPLKELFGQMLATKADPNKGRQMPEHPGSKALNFFTVASPIASHVPPAAGAAIS 159
Query: 679 HKYRADGGVTFALYGDGAANQGQLF 753
K G V +GDGA ++G +
Sbjct: 160 MKLLRTGQVAVCTFGDGATSEGDWY 184
>UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=1; Mycoplasma penetrans|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
penetrans
Length = 359
Score = 34.7 bits (76), Expect = 2.7
Identities = 16/49 (32%), Positives = 24/49 (48%)
Frame = +1
Query: 613 NFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
NF N +G Q AG+ A Y+ V + + GDG +G+ +EA
Sbjct: 126 NFLPFNIPIGTQYSHAAGIGIALNYQNKPNVAYTVIGDGGTAEGEFYEA 174
>UniRef50_Q7TZU3 Cluster: PE-PGRS FAMILY PROTEIN; n=28;
Mycobacterium|Rep: PE-PGRS FAMILY PROTEIN -
Mycobacterium bovis
Length = 1018
Score = 34.7 bits (76), Expect = 2.7
Identities = 28/72 (38%), Positives = 34/72 (47%)
Frame = +1
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADG 699
G G S LTG +G + G GGS+ L+G GG+G GA L GV G
Sbjct: 311 GAGGAGGTSGLTG--SGVAGGAGGSVGLWGSGGAGGDG--GAATSL-LGVGMNAGAGGAG 365
Query: 700 GVTFALYGDGAA 735
G LYG+G A
Sbjct: 366 GNAGLLYGNGGA 377
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 34.7 bits (76), Expect = 2.7
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Frame = +1
Query: 625 GNGI-VGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
GN + +G QV AGVA+ K R V + GDG ++G +E
Sbjct: 128 GNCVPIGTQVGHAAGVAYTFKLRQAPNVAVCILGDGGTSKGDFYE 172
Score = 34.3 bits (75), Expect = 3.6
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
Frame = +2
Query: 323 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
L LY + + R+ + + + + I F GQEA+ VG+ AMR D ++ +YR H
Sbjct: 36 LPLYRAMVLTRQFDLKAIAMQRTGQIGTFASAL-GQEAIGVGVATAMRRDDVLVPSYRDH 94
Query: 503 ------GWLISWALVCWG 538
G ++ +L+ WG
Sbjct: 95 AAQFVRGVTMTESLLYWG 112
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 34.7 bits (76), Expect = 2.7
Identities = 20/60 (33%), Positives = 31/60 (51%)
Frame = +2
Query: 323 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 502
L LY + + R +T + L + + F GQEA+ VG+ +AMR D + +YR H
Sbjct: 36 LALYRAMVLTRAFDTKAIALQRTGKLGTFASSV-GQEAIGVGVASAMRAEDVLFPSYRDH 94
>UniRef50_Q5NA48 Cluster: Putative chromatin remodeling factor CHD3;
n=2; Oryza sativa|Rep: Putative chromatin remodeling
factor CHD3 - Oryza sativa subsp. japonica (Rice)
Length = 1150
Score = 34.7 bits (76), Expect = 2.7
Identities = 17/43 (39%), Positives = 24/43 (55%)
Frame = -1
Query: 720 VQSERDSPVGAVLVGEGHSGSQRNLRTNNPVATIEVASVQMHG 592
V++ SP+GA EG GS RNL+ TI+ A+ + HG
Sbjct: 65 VETSEASPLGAPEEDEGKPGSTRNLKRLRKTITIDSAAAEEHG 107
>UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=33; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus stearothermophilus
(Geobacillus stearothermophilus)
Length = 369
Score = 34.7 bits (76), Expect = 2.7
Identities = 17/41 (41%), Positives = 20/41 (48%)
Frame = +1
Query: 634 IVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
I+GAQ AGVA K R V GDG +QG +E
Sbjct: 144 IIGAQYIQAAGVALGLKMRGKKAVAITYTGDGGTSQGDFYE 184
>UniRef50_Q4A2S6 Cluster: Putative membrane protein precursor; n=1;
Emiliania huxleyi virus 86|Rep: Putative membrane
protein precursor - Emiliania huxleyi virus 86
Length = 430
Score = 34.3 bits (75), Expect = 3.6
Identities = 20/62 (32%), Positives = 24/62 (38%)
Frame = -2
Query: 704 TPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTL 525
+PPS +W +P P P + PP P PP P P P S S P
Sbjct: 20 SPPSHPPIWPHQSPPPPSNPPPPLSPPPSLPPPPPSPPPPSPPSLPPWWPNVSPSPPPPT 79
Query: 524 TP 519
TP
Sbjct: 80 TP 81
>UniRef50_Q8KWB9 Cluster: RB123; n=1; Ruegeria sp. PR1b|Rep: RB123 -
Ruegeria sp. PR1b
Length = 271
Score = 34.3 bits (75), Expect = 3.6
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = +1
Query: 628 NGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
NG +G + G G+A + R + + L GDG N+G ++EA
Sbjct: 113 NGSLGQGLSYGLGMALGMQKRGEDRRVYVLMGDGECNEGSVWEA 156
>UniRef50_Q756F4 Cluster: DNA repair and recombination protein
RAD52; n=1; Eremothecium gossypii|Rep: DNA repair and
recombination protein RAD52 - Ashbya gossypii (Yeast)
(Eremothecium gossypii)
Length = 435
Score = 34.3 bits (75), Expect = 3.6
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Frame = -2
Query: 665 PAPNGTCAPTIPLP-P*KLRPYKCMEPPLPREQPVLRPVSSESTPSTL 525
PAP AP P P P +RP P P E P+ RP SSE+ L
Sbjct: 189 PAPKKRNAPLPPAPRPGAMRPEAAHAAPAPSEPPLERPRSSENDQEDL 236
>UniRef50_UPI0000DB7674 Cluster: PREDICTED: hypothetical protein;
n=2; Eumetazoa|Rep: PREDICTED: hypothetical protein -
Apis mellifera
Length = 441
Score = 33.9 bits (74), Expect = 4.7
Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 4/66 (6%)
Frame = -2
Query: 704 TPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPY----KCMEPPLPREQPVLRPVSSEST 537
+PPS + P+P T P+ P PP P PP P PV RP S S
Sbjct: 224 SPPSPPVTRPPSPPSPPITRPPSPPSPPITRPPSPPSPPITRPPSPPSPPVTRPPSPPSP 283
Query: 536 PSTLTP 519
P T P
Sbjct: 284 PVTRPP 289
Score = 33.9 bits (74), Expect = 4.7
Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 4/66 (6%)
Frame = -2
Query: 704 TPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPY----KCMEPPLPREQPVLRPVSSEST 537
+PPS + P+P T P+ P PP P PP P PV RP S S
Sbjct: 235 SPPSPPITRPPSPPSPPITRPPSPPSPPITRPPSPPSPPVTRPPSPPSPPVTRPPSPPSP 294
Query: 536 PSTLTP 519
P T P
Sbjct: 295 PVTRPP 300
>UniRef50_Q9DYE3 Cluster: Membrane virion glycoprotein 150; n=2;
Gammaherpesvirinae|Rep: Membrane virion glycoprotein 150
- Murine herpesvirus 72
Length = 483
Score = 33.9 bits (74), Expect = 4.7
Identities = 20/63 (31%), Positives = 27/63 (42%)
Frame = -2
Query: 707 VTPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPST 528
+TPP+ +PA + PT P P K P ++PP P + ESTP T
Sbjct: 268 LTPPTEPPTPETVSPADSPVPQPTAPAEPSKPEPTPPVDPPATEPNIPADPSTPESTPPT 327
Query: 527 LTP 519
P
Sbjct: 328 DPP 330
>UniRef50_Q2IMK5 Cluster: DnaJ like heat shock protein with
tetratricopeptide repeats; n=1; Anaeromyxobacter
dehalogenans 2CP-C|Rep: DnaJ like heat shock protein
with tetratricopeptide repeats - Anaeromyxobacter
dehalogenans (strain 2CP-C)
Length = 605
Score = 33.9 bits (74), Expect = 4.7
Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Frame = -2
Query: 707 VTPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCM-EPPLPREQPVLRPVSSESTPS 531
V PP AR ATP P PT P+PP P PP PR PV + +TP+
Sbjct: 320 VAPPPAR----AATPTPTPRPTPT-PVPPPAAAPAAAAPRPPPPRPPPVAAAPAPRTTPA 374
>UniRef50_Q2CJ96 Cluster: Putative transketolase alpha subunit
protein; n=1; Oceanicola granulosus HTCC2516|Rep:
Putative transketolase alpha subunit protein -
Oceanicola granulosus HTCC2516
Length = 308
Score = 33.9 bits (74), Expect = 4.7
Identities = 17/57 (29%), Positives = 28/57 (49%)
Frame = +1
Query: 589 GSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G+ H G + NG +G + AG+A+ + R + G + DG +GQ +EA
Sbjct: 130 GAEHSPGMEVH--NGTLGIGLSTAAGLAWGRRRRGESGRVWVFMSDGEVQEGQTWEA 184
>UniRef50_Q02BA9 Cluster: Transketolase domain protein; n=1;
Solibacter usitatus Ellin6076|Rep: Transketolase domain
protein - Solibacter usitatus (strain Ellin6076)
Length = 255
Score = 33.9 bits (74), Expect = 4.7
Identities = 16/52 (30%), Positives = 25/52 (48%)
Frame = +1
Query: 604 YGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
+ R+ G +G +P AG+A H++R G F L D +G +EA
Sbjct: 92 WSRDIPFATGSLGHGLPDAAGIALGHRFRGRSGRVFCLTSDAEWQEGSNWEA 143
>UniRef50_A3U4U6 Cluster: Transketolase, N-terminal subunit; n=19;
Bacteroidetes|Rep: Transketolase, N-terminal subunit -
Croceibacter atlanticus HTCC2559
Length = 293
Score = 33.9 bits (74), Expect = 4.7
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +1
Query: 628 NGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEAY 762
+G +G + + G A + K D + +AL GDG +GQ +EA+
Sbjct: 129 SGSLGQGLSVAIGAASSKKLNGDDKLVYALLGDGELQEGQNWEAF 173
>UniRef50_A0H3S4 Cluster: Putative uncharacterized protein; n=1;
Chloroflexus aggregans DSM 9485|Rep: Putative
uncharacterized protein - Chloroflexus aggregans DSM
9485
Length = 400
Score = 33.9 bits (74), Expect = 4.7
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Frame = -2
Query: 698 PSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTP 519
P+ W+ P P G A PP + RP P L R QPV + ST +P
Sbjct: 187 PTGAVRWSDDRPLPTGAVAQPSASPPARCRPVPWRSPALHR-QPVADRCRGAAQRSTASP 245
Query: 518 M-R*AIRDNDTR 486
+ A+R +D R
Sbjct: 246 LPTGAVRWSDDR 257
>UniRef50_Q41071 Cluster: Arabinogalactan-like protein; n=2;
Pinaceae|Rep: Arabinogalactan-like protein - Pinus taeda
(Loblolly pine)
Length = 168
Score = 33.9 bits (74), Expect = 4.7
Identities = 22/63 (34%), Positives = 25/63 (39%), Gaps = 3/63 (4%)
Frame = -2
Query: 698 PSARYLWAKATPAPNGTCAPTIPLPP*KLR---PYKCMEPPLPREQPVLRPVSSESTPST 528
PSA + TPAP T APT P + P PP+ PV P S P
Sbjct: 26 PSASPTKSPTTPAPTTTAAPTTTAAPPTITATPPTTTATPPVSTPPPVSSPPPVTSPPPA 85
Query: 527 LTP 519
TP
Sbjct: 86 ATP 88
>UniRef50_Q9VDD2 Cluster: CG17299-PF, isoform F; n=18; Diptera|Rep:
CG17299-PF, isoform F - Drosophila melanogaster (Fruit
fly)
Length = 1400
Score = 33.9 bits (74), Expect = 4.7
Identities = 18/42 (42%), Positives = 26/42 (61%)
Frame = -1
Query: 678 GEGHSGSQRNLRTNNPVATIEVASVQMHGTSLAPGATGPAPR 553
GEG GS+ +LR ++PV +VA V++ T+ A T P PR
Sbjct: 1222 GEGVGGSESSLRASDPVLLRKVAEVEIPATAAAATTTTP-PR 1262
>UniRef50_Q8INB9 Cluster: RAC serine/threonine-protein kinase; n=8;
Bilateria|Rep: RAC serine/threonine-protein kinase -
Drosophila melanogaster (Fruit fly)
Length = 611
Score = 33.9 bits (74), Expect = 4.7
Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 566 PVAPGAREVPCICTDAT--SMVATGLLVRRFRWEPEWPSPTSTAPTGESRSLCTET 727
P G+ + I + +T + T +F W+ WPS TS APT +S ++ T
Sbjct: 31 PTTTGSNIINIIYSQSTHPNSSPTSGSAEKFSWQQSWPSRTSAAPTHDSGTMSINT 86
>UniRef50_UPI000069F43F Cluster: Short transient receptor potential
channel 6 (TrpC6).; n=1; Xenopus tropicalis|Rep: Short
transient receptor potential channel 6 (TrpC6). -
Xenopus tropicalis
Length = 806
Score = 33.5 bits (73), Expect = 6.2
Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Frame = +2
Query: 170 RKHNHESDCTGCSDKRKIQHEKRGDIRNQPYKLHKLDQGPATSATLTSED----ALKLYE 337
R H++ CT CS+K+K H+ R++ +K PA +L+SED AL+L
Sbjct: 173 RPHDYFCKCTECSEKQK--HDSFSHSRSR-INAYKGLASPA-YLSLSSEDPVMTALELSN 228
Query: 338 QLTILRRIETASGNLYKE 391
+L +L IE N YK+
Sbjct: 229 ELAVLANIEKEFKNDYKK 246
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 33.5 bits (73), Expect = 6.2
Identities = 17/34 (50%), Positives = 21/34 (61%)
Frame = +1
Query: 628 NGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDG 729
N I+G+ V LGAG+A A K + VT A GDG
Sbjct: 132 NIIIGSSVNLGAGLALASKMQNKKEVTIATIGDG 165
>UniRef50_Q07IS1 Cluster: Transketolase, central region; n=1;
Rhodopseudomonas palustris BisA53|Rep: Transketolase,
central region - Rhodopseudomonas palustris (strain
BisA53)
Length = 645
Score = 33.5 bits (73), Expect = 6.2
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Frame = +1
Query: 631 GIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA-YTCLNYGT 783
G +G + G+ A++ G F L GDG +GQ++E+ + N+GT
Sbjct: 135 GSLGMGISKAKGMLAANRLHGSSGRVFVLTGDGELQEGQIWESLISAANHGT 186
>UniRef50_A6GFK2 Cluster: Modular polyketide synthase; n=1;
Plesiocystis pacifica SIR-1|Rep: Modular polyketide
synthase - Plesiocystis pacifica SIR-1
Length = 2181
Score = 33.5 bits (73), Expect = 6.2
Identities = 30/84 (35%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +1
Query: 538 VLSELTGRRTGCSRGKGGSMHLYGRNFYGG-NGIVGAQVPLGAGVAFAHKYRADGGVTFA 714
V +ELTG RTG G G S + + R GG +G Q AG AH G TFA
Sbjct: 75 VPAELTGTRTGVFMGIGSSDYDFRRRDVGGAYTYLGTQASFVAG-RVAHSLGL-RGPTFA 132
Query: 715 LYGDGAANQGQLFEAYTCLNYGTC 786
L + + L A L +G C
Sbjct: 133 LDTGCSTSLVALHSACRALQHGEC 156
>UniRef50_A0L593 Cluster: Transketolase domain protein; n=2;
Proteobacteria|Rep: Transketolase domain protein -
Magnetococcus sp. (strain MC-1)
Length = 268
Score = 33.5 bits (73), Expect = 6.2
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = +1
Query: 628 NGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
NG +G + +GAG+A A K + + GDG N+G ++EA
Sbjct: 111 NGALGHGLGVGAGMAIALKAQGSQARVCVVCGDGEMNEGSVWEA 154
>UniRef50_O15032 Cluster: FERM and PDZ domain-containing protein 4;
n=24; Tetrapoda|Rep: FERM and PDZ domain-containing
protein 4 - Homo sapiens (Human)
Length = 1379
Score = 33.5 bits (73), Expect = 6.2
Identities = 23/69 (33%), Positives = 26/69 (37%)
Frame = +2
Query: 482 ITAYRCHGWLISWALVCWGCSRS*RGAGPVAPGAREVPCICTDATSMVATGLLVRRFRWE 661
+ A R G L SW C GC R G + AR P C D S V L
Sbjct: 18 VAATRAPGALRSWPWGCGGCC-CWREKGRRSCRARGSPAACMDVFSFVKIAKLSSHRTKS 76
Query: 662 PEWPSPTST 688
WP P+ T
Sbjct: 77 SGWPPPSGT 85
>UniRef50_Q7SBI9 Cluster: Predicted protein; n=1; Neurospora
crassa|Rep: Predicted protein - Neurospora crassa
Length = 1456
Score = 33.5 bits (73), Expect = 6.2
Identities = 21/53 (39%), Positives = 23/53 (43%), Gaps = 2/53 (3%)
Frame = -2
Query: 671 ATPAPNGTCAPTIPLPP*KLRPYKCMEP--PLPREQPVLRPVSSESTPSTLTP 519
ATP+P T P IP P R M P P P RPVSS + S P
Sbjct: 1367 ATPSPPATAPPAIPRVPVSSRNSSFMPPAPPTMAPPPPPRPVSSSTLASASAP 1419
>UniRef50_Q8ZW78 Cluster: Transketolase; n=5; Thermoproteaceae|Rep:
Transketolase - Pyrobaculum aerophilum
Length = 267
Score = 33.5 bits (73), Expect = 6.2
Identities = 13/45 (28%), Positives = 26/45 (57%)
Frame = +1
Query: 628 NGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEAY 762
+G +G + L G+A K + + G + + GDG ++GQ +E++
Sbjct: 116 SGSLGQGISLAVGLALGMKIKGEKGRVYLVVGDGELDEGQSWESF 160
>UniRef50_A0RTR4 Cluster: Transketolase, N-terminal subunit; n=1;
Cenarchaeum symbiosum|Rep: Transketolase, N-terminal
subunit - Cenarchaeum symbiosum
Length = 504
Score = 33.5 bits (73), Expect = 6.2
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +1
Query: 607 GRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G F GG+ +G + G+A A K G + + GDG +++GQ++EA
Sbjct: 74 GVEFCGGS--LGIGLSFSLGIALAAKIDGRGHRVYTILGDGESDEGQVWEA 122
>UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha, mitochondrial precursor; n=29; Euteleostomi|Rep:
2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial precursor - Homo sapiens (Human)
Length = 445
Score = 33.5 bits (73), Expect = 6.2
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Frame = +1
Query: 580 GKGGSMHL-YG---RNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQ 747
GKG M + YG R+F + + Q+P G A+A K V +G+GAA++G
Sbjct: 186 GKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEG- 244
Query: 748 LFEAYTCLNYGTCL 789
+A+ N+ L
Sbjct: 245 --DAHAGFNFAATL 256
>UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=37; Firmicutes|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Bacillus subtilis
Length = 330
Score = 33.5 bits (73), Expect = 6.2
Identities = 15/44 (34%), Positives = 22/44 (50%)
Frame = +1
Query: 625 GNGIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFE 756
G+ V QVP G+A A + F +G+G++NQG E
Sbjct: 121 GSSPVTTQVPHAVGIALAGRMEKKDIAAFVTFGEGSSNQGDFHE 164
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 33.1 bits (72), Expect = 8.2
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Frame = +2
Query: 272 KLDQGPATSATLTSEDALK-LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 448
+L P + S+ AL LY Q+ ++RR E +L ++ + + +GQEA VG
Sbjct: 26 RLTDTPTEGLRIPSDAALTGLYRQMVLVRRFEAQVTHLTRQGRLATYPSA-AGQEAAEVG 84
Query: 449 MRAAMRDADSVITAYR 496
A+ D + YR
Sbjct: 85 ATTALAPNDWLFPTYR 100
>UniRef50_Q7NNH9 Cluster: Glr0432 protein; n=1; Gloeobacter
violaceus|Rep: Glr0432 protein - Gloeobacter violaceus
Length = 378
Score = 33.1 bits (72), Expect = 8.2
Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 5/73 (6%)
Frame = -2
Query: 707 VTPPSARYL---WAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLR--PVSSE 543
+ PPSA L A+ P+PNGT AP +PLPP PP ++Q +L+ P S
Sbjct: 158 IQPPSAPPLPQITAQPAPSPNGT-AP-LPLPP------VSTPPPPSQQQTMLQMPPAPSP 209
Query: 542 STPSTLTPMR*AI 504
S P+ P R A+
Sbjct: 210 SAPTVPPPPRPAV 222
>UniRef50_Q2Y5G9 Cluster: TonB-like; n=1; Nitrosospira multiformis
ATCC 25196|Rep: TonB-like - Nitrosospira multiformis
(strain ATCC 25196 / NCIMB 11849)
Length = 353
Score = 33.1 bits (72), Expect = 8.2
Identities = 16/55 (29%), Positives = 23/55 (41%)
Frame = -2
Query: 683 LWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTP 519
LW+ PAP P PP + P ++PP + P P+ TP+ P
Sbjct: 49 LWSSLPPAPAPVVRAAPPPPPKPVEPMPEVKPPETKPLPKPEPLPQPETPTPSKP 103
>UniRef50_Q1QHE7 Cluster: OmpA/MotB precursor; n=2; Nitrobacter|Rep:
OmpA/MotB precursor - Nitrobacter hamburgensis (strain
X14 / DSM 10229)
Length = 673
Score = 33.1 bits (72), Expect = 8.2
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Frame = -2
Query: 710 NVTPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPV-LRPVSSESTP 534
+ TPP+A KA PAP P P PP P PP P + P +++S P
Sbjct: 127 HATPPAAPAA-PKAAPAPKPATPPVAPKPP---APPTAAPPPSPSKGTTPPPPAATKSAP 182
Query: 533 STLTP 519
+T P
Sbjct: 183 TTPAP 187
>UniRef50_A6C1X9 Cluster: Transketolase-like protein; n=1;
Planctomyces maris DSM 8797|Rep: Transketolase-like
protein - Planctomyces maris DSM 8797
Length = 280
Score = 33.1 bits (72), Expect = 8.2
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = +1
Query: 631 GIVGAQVPLGAGVAFAHKYRADGGVTFALYGDGAANQGQLFEA 759
G +G + LG G A + +G F + GDG +GQ++EA
Sbjct: 123 GSLGQGLSLGIGQALGARLNDNGSNVFVVIGDGEMGEGQVWEA 165
>UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Dehydrogenase, E1 component - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 315
Score = 33.1 bits (72), Expect = 8.2
Identities = 19/62 (30%), Positives = 29/62 (46%)
Frame = +2
Query: 329 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 508
++ +L + R +ET +E+ G+ H GQEA +G AA+ D V R W
Sbjct: 12 MFHKLAVSRAVETLMLRHTREERFSGWWHPGEGQEAAPIGATAALEADDYVWYQGRGCAW 71
Query: 509 LI 514
I
Sbjct: 72 AI 73
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 33.1 bits (72), Expect = 8.2
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 275 LDQGPATSATLTSEDALKL---YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 445
L + P SA DA KL Y + +RR + + L ++ + + L +GQEA +
Sbjct: 45 LGEDPVFSAYANRLDAEKLRGFYADMAAIRRFDQEATALQRQGQLALWVPL-TGQEAAQI 103
Query: 446 GMRAAMRDADSVITAYRCHG 505
G A + D + YR HG
Sbjct: 104 GSGRASQPQDYIFPTYREHG 123
>UniRef50_Q9VEJ1 Cluster: CG5836-PA; n=10; Eumetazoa|Rep: CG5836-PA
- Drosophila melanogaster (Fruit fly)
Length = 787
Score = 33.1 bits (72), Expect = 8.2
Identities = 20/54 (37%), Positives = 27/54 (50%)
Frame = -2
Query: 677 AKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTPM 516
A PAP GT AP P+PP + +PP P +P+ P+ P TL P+
Sbjct: 685 AAYVPAPPGTQAPP-PMPPPLMPWMSAPQPPPPATEPLNPPI-----PGTLPPL 732
>UniRef50_Q4E016 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 415
Score = 33.1 bits (72), Expect = 8.2
Identities = 21/85 (24%), Positives = 38/85 (44%)
Frame = +2
Query: 257 PYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 436
P+ H+ + LT+ AL + R + + SG+ + ++ G Y GQ+A
Sbjct: 154 PFLAHQEKEMEGREEMLTAIAALLEKDTAFGPRFLSSLSGDALRSLLVIGTTQEYFGQDA 213
Query: 437 VAVGMRAAMRDADSVITAYRCHGWL 511
V +RA +D D I++ W+
Sbjct: 214 VEAQLRAVDKDQDDNISSQDYDAWV 238
>UniRef50_A7F3W9 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Sclerotinia sclerotiorum 1980
Length = 1585
Score = 33.1 bits (72), Expect = 8.2
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = -2
Query: 674 KATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSS 546
K+ P P +PLP L P+K + P +P QP PVSS
Sbjct: 490 KSVSDPEPVPLPAMPLPSMMLEPHK-LRPVIPDSQPEASPVSS 531
>UniRef50_P03073 Cluster: Large T antigen; n=4; root|Rep: Large T
antigen - Murine polyomavirus (strain A2) (MPyV)
Length = 785
Score = 33.1 bits (72), Expect = 8.2
Identities = 14/37 (37%), Positives = 19/37 (51%)
Frame = +2
Query: 653 RWEPEWPSPTSTAPTGESRSLCTETEPPIRVNSSKPT 763
+W+P + SP TA + E L EP + N S PT
Sbjct: 122 KWDPSYQSPPKTAESSEQPDLFCYEEPLLSPNPSSPT 158
>UniRef50_Q5H9T9 Cluster: Uncharacterized protein C14orf155; n=4;
Catarrhini|Rep: Uncharacterized protein C14orf155 - Homo
sapiens (Human)
Length = 837
Score = 33.1 bits (72), Expect = 8.2
Identities = 18/65 (27%), Positives = 26/65 (40%)
Frame = -2
Query: 713 ANVTPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTP 534
A V PP A A+ P P + PP + P + PP ++P +E P
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP 679
Query: 533 STLTP 519
S + P
Sbjct: 680 SEVQP 684
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 791,722,422
Number of Sequences: 1657284
Number of extensions: 16749116
Number of successful extensions: 65768
Number of sequences better than 10.0: 178
Number of HSP's better than 10.0 without gapping: 59628
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 65372
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 67496806780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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