Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV30826
(660 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein. 166 5e-41
AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens ... 166 5e-41
AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2 prot... 166 5e-41
AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1 prot... 163 4e-40
AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein. 163 4e-40
AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens ... 161 2e-39
AK022027-1|BAB13955.1| 234|Homo sapiens protein ( Homo sapiens ... 138 2e-32
AK001440-1|BAA91692.1| 234|Homo sapiens protein ( Homo sapiens ... 138 2e-32
AL831940-1|CAD38592.1| 215|Homo sapiens hypothetical protein pr... 127 4e-29
AK075148-1|BAC11434.1| 170|Homo sapiens protein ( Homo sapiens ... 91 2e-18
AK074907-1|BAC11283.1| 170|Homo sapiens protein ( Homo sapiens ... 91 2e-18
>BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein.
Length = 418
Score = 166 bits (404), Expect = 5e-41
Identities = 78/84 (92%), Positives = 81/84 (96%)
Frame = +3
Query: 3 SGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLATRPDKVRALREAFYR 182
SGISLFIATNICETIVWKAFSP T+NTGRGTEFEGAVIALFHLLATR DKVRALREAFYR
Sbjct: 177 SGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYR 236
Query: 183 QNLPNLMNLLATVLVFAIVIYFQG 254
QNLPNLMNL+ATV VFA+VIYFQG
Sbjct: 237 QNLPNLMNLIATVFVFAVVIYFQG 260
Score = 138 bits (334), Expect = 2e-32
Identities = 67/86 (77%), Positives = 70/86 (81%)
Frame = +2
Query: 251 GLRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVN 430
G RVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+FSGNFLVN
Sbjct: 260 GFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVN 319
Query: 431 VLGVWADXXXXXXXXXXXXXXLCYYL 508
+LG WAD LCYYL
Sbjct: 320 LLGQWADVSGGGPARSYPVGGLCYYL 345
Score = 90.6 bits (215), Expect = 4e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES+ I DPVH ++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 346 SPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 396
>AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens
cDNA FLJ12578 fis, clone NT2RM4001054, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 437
Score = 166 bits (404), Expect = 5e-41
Identities = 78/84 (92%), Positives = 81/84 (96%)
Frame = +3
Query: 3 SGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLATRPDKVRALREAFYR 182
SGISLFIATNICETIVWKAFSP T+NTGRGTEFEGAVIALFHLLATR DKVRALREAFYR
Sbjct: 177 SGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYR 236
Query: 183 QNLPNLMNLLATVLVFAIVIYFQG 254
QNLPNLMNL+ATV VFA+VIYFQG
Sbjct: 237 QNLPNLMNLIATVFVFAVVIYFQG 260
Score = 138 bits (334), Expect = 2e-32
Identities = 67/86 (77%), Positives = 70/86 (81%)
Frame = +2
Query: 251 GLRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVN 430
G RVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+FSGNFLVN
Sbjct: 260 GFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVN 319
Query: 431 VLGVWADXXXXXXXXXXXXXXLCYYL 508
+LG WAD LCYYL
Sbjct: 320 LLGQWADVSGGGPARSYPVGGLCYYL 345
Score = 90.6 bits (215), Expect = 4e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES+ I DPVH ++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 346 SPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 396
>AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2
protein.
Length = 476
Score = 166 bits (404), Expect = 5e-41
Identities = 78/84 (92%), Positives = 81/84 (96%)
Frame = +3
Query: 3 SGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLATRPDKVRALREAFYR 182
SGISLFIATNICETIVWKAFSP T+NTGRGTEFEGAVIALFHLLATR DKVRALREAFYR
Sbjct: 177 SGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYR 236
Query: 183 QNLPNLMNLLATVLVFAIVIYFQG 254
QNLPNLMNL+ATV VFA+VIYFQG
Sbjct: 237 QNLPNLMNLIATVFVFAVVIYFQG 260
Score = 138 bits (334), Expect = 2e-32
Identities = 67/86 (77%), Positives = 70/86 (81%)
Frame = +2
Query: 251 GLRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVN 430
G RVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+FSGNFLVN
Sbjct: 260 GFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVN 319
Query: 431 VLGVWADXXXXXXXXXXXXXXLCYYL 508
+LG WAD LCYYL
Sbjct: 320 LLGQWADVSGGGPARSYPVGGLCYYL 345
Score = 90.6 bits (215), Expect = 4e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES+ I DPVH ++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 346 SPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 396
>AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1
protein.
Length = 476
Score = 163 bits (397), Expect = 4e-40
Identities = 76/84 (90%), Positives = 80/84 (95%)
Frame = +3
Query: 3 SGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLATRPDKVRALREAFYR 182
SGISLFIATNICETIVWKAFSP TVNTGRG EFEGA+IALFHLLATR DKVRALREAFYR
Sbjct: 177 SGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYR 236
Query: 183 QNLPNLMNLLATVLVFAIVIYFQG 254
QNLPNLMNL+AT+ VFA+VIYFQG
Sbjct: 237 QNLPNLMNLIATIFVFAVVIYFQG 260
Score = 129 bits (312), Expect = 8e-30
Identities = 61/86 (70%), Positives = 68/86 (79%)
Frame = +2
Query: 251 GLRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVN 430
G RVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSNLYVISQML+ +FSGN LV+
Sbjct: 260 GFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVS 319
Query: 431 VLGVWADXXXXXXXXXXXXXXLCYYL 508
+LG W+D LCYYL
Sbjct: 320 LLGTWSDTSSGGPARAYPVGGLCYYL 345
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES + DPVHA++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 346 SPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 396
>AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein.
Length = 476
Score = 163 bits (397), Expect = 4e-40
Identities = 76/84 (90%), Positives = 80/84 (95%)
Frame = +3
Query: 3 SGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLATRPDKVRALREAFYR 182
SGISLFIATNICETIVWKAFSP TVNTGRG EFEGA+IALFHLLATR DKVRALREAFYR
Sbjct: 177 SGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYR 236
Query: 183 QNLPNLMNLLATVLVFAIVIYFQG 254
QNLPNLMNL+AT+ VFA+VIYFQG
Sbjct: 237 QNLPNLMNLIATIFVFAVVIYFQG 260
Score = 129 bits (312), Expect = 8e-30
Identities = 61/86 (70%), Positives = 68/86 (79%)
Frame = +2
Query: 251 GLRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVN 430
G RVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSNLYVISQML+ +FSGN LV+
Sbjct: 260 GFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVS 319
Query: 431 VLGVWADXXXXXXXXXXXXXXLCYYL 508
+LG W+D LCYYL
Sbjct: 320 LLGTWSDTSSGGPARAYPVGGLCYYL 345
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES + DPVHA++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 346 SPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 396
>AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens
cDNA FLJ90447 fis, clone NT2RP3001240, highly similar to
Canis familiaris sec61 homologue mRNA. ).
Length = 356
Score = 161 bits (391), Expect = 2e-39
Identities = 75/84 (89%), Positives = 79/84 (94%)
Frame = +3
Query: 3 SGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLATRPDKVRALREAFYR 182
SGISLFIATNICETIVWKAFSP TVNTGRG EFEGA+IALFHLLATR DKVRALREA YR
Sbjct: 57 SGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREALYR 116
Query: 183 QNLPNLMNLLATVLVFAIVIYFQG 254
QNLPNLMNL+AT+ VFA+VIYFQG
Sbjct: 117 QNLPNLMNLIATIFVFAVVIYFQG 140
Score = 129 bits (312), Expect = 8e-30
Identities = 61/86 (70%), Positives = 68/86 (79%)
Frame = +2
Query: 251 GLRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVN 430
G RVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSNLYVISQML+ +FSGN LV+
Sbjct: 140 GFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVS 199
Query: 431 VLGVWADXXXXXXXXXXXXXXLCYYL 508
+LG W+D LCYYL
Sbjct: 200 LLGTWSDTSSGGPARAYPVGGLCYYL 225
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES + DPVHA++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 226 SPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 276
>AK022027-1|BAB13955.1| 234|Homo sapiens protein ( Homo sapiens
cDNA FLJ11965 fis, clone HEMBB1001112, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 234
Score = 138 bits (334), Expect = 2e-32
Identities = 67/86 (77%), Positives = 70/86 (81%)
Frame = +2
Query: 251 GLRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVN 430
G RVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+FSGNFLVN
Sbjct: 18 GFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVN 77
Query: 431 VLGVWADXXXXXXXXXXXXXXLCYYL 508
+LG WAD LCYYL
Sbjct: 78 LLGQWADVSGGGPARSYPVGGLCYYL 103
Score = 90.6 bits (215), Expect = 4e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES+ I DPVH ++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 104 SPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 154
Score = 35.9 bits (79), Expect = 0.13
Identities = 15/18 (83%), Positives = 17/18 (94%)
Frame = +3
Query: 201 MNLLATVLVFAIVIYFQG 254
MNL+ATV VFA+VIYFQG
Sbjct: 1 MNLIATVFVFAVVIYFQG 18
>AK001440-1|BAA91692.1| 234|Homo sapiens protein ( Homo sapiens
cDNA FLJ10578 fis, clone NT2RP2003433, highly similar to
PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT. ).
Length = 234
Score = 138 bits (334), Expect = 2e-32
Identities = 67/86 (77%), Positives = 70/86 (81%)
Frame = +2
Query: 251 GLRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVN 430
G RVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+FSGNFLVN
Sbjct: 18 GFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVN 77
Query: 431 VLGVWADXXXXXXXXXXXXXXLCYYL 508
+LG WAD LCYYL
Sbjct: 78 LLGQWADVSGGGPARSYPVGGLCYYL 103
Score = 90.6 bits (215), Expect = 4e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES+ I DPVH ++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 104 SPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 154
Score = 35.9 bits (79), Expect = 0.13
Identities = 15/18 (83%), Positives = 17/18 (94%)
Frame = +3
Query: 201 MNLLATVLVFAIVIYFQG 254
MNL+ATV VFA+VIYFQG
Sbjct: 1 MNLIATVFVFAVVIYFQG 18
>AL831940-1|CAD38592.1| 215|Homo sapiens hypothetical protein
protein.
Length = 215
Score = 127 bits (306), Expect = 4e-29
Identities = 60/84 (71%), Positives = 67/84 (79%)
Frame = +2
Query: 257 RVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFSGNFLVNVL 436
RVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSNLYVISQML+ +FSGN LV++L
Sbjct: 1 RVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLL 60
Query: 437 GVWADXXXXXXXXXXXXXXLCYYL 508
G W+D LCYYL
Sbjct: 61 GTWSDTSSGGPARAYPVGGLCYYL 84
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES + DPVHA++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 85 SPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 135
>AK075148-1|BAC11434.1| 170|Homo sapiens protein ( Homo sapiens
cDNA FLJ90667 fis, clone PLACE1005410, highly similar to
Protein transport protein Sec61 alpha subunitisoform 1.
).
Length = 170
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES + DPVHA++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 40 SPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 90
Score = 39.9 bits (89), Expect = 0.008
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +2
Query: 392 MLAVKFSGNFLVNVLGVWADXXXXXXXXXXXXXXLCYYL 508
ML+ +FSGN LV++LG W+D LCYYL
Sbjct: 1 MLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYL 39
>AK074907-1|BAC11283.1| 170|Homo sapiens protein ( Homo sapiens
cDNA FLJ90426 fis, clone NT2RP3000460, highly similar to
Protein transport protein Sec61 alpha subunitisoform 1.
).
Length = 170
Score = 91.5 bits (217), Expect = 2e-18
Identities = 39/51 (76%), Positives = 46/51 (90%)
Frame = +1
Query: 508 APPESLAHIAHDPVHALLYVLFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 660
+PPES + DPVHA++Y++FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 40 SPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 90
Score = 39.9 bits (89), Expect = 0.008
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +2
Query: 392 MLAVKFSGNFLVNVLGVWADXXXXXXXXXXXXXXLCYYL 508
ML+ +FSGN LV++LG W+D LCYYL
Sbjct: 1 MLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYL 39
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 96,824,403
Number of Sequences: 237096
Number of extensions: 1998121
Number of successful extensions: 4192
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 3979
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4178
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7422585720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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