Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV30781
(730 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 97 6e-20
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 97 6e-20
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 97 6e-20
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 97 6e-20
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 97 6e-20
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 97 6e-20
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 97 6e-20
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 87 8e-17
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 86 1e-16
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 86 1e-16
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 86 1e-16
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 85 3e-16
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 85 3e-16
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 79 2e-14
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 79 2e-14
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 79 2e-14
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 79 2e-14
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 79 2e-14
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 79 2e-14
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 79 2e-14
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 79 2e-14
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 79 2e-14
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 79 2e-14
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 79 2e-14
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 79 2e-14
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 79 2e-14
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 79 2e-14
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 79 2e-14
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 79 2e-14
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 75 3e-13
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 75 3e-13
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 75 3e-13
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 75 3e-13
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 75 3e-13
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 75 3e-13
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 75 3e-13
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 75 3e-13
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 73 8e-13
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 73 1e-12
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 59 2e-08
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 38 0.028
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 38 0.049
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 37 0.085
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 37 0.085
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 37 0.085
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 37 0.085
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 37 0.085
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 37 0.085
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 37 0.085
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 37 0.085
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 37 0.085
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 37 0.085
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 37 0.085
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 37 0.085
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 35 0.26
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.34
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.34
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.34
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.34
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 35 0.34
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 35 0.34
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 35 0.34
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 35 0.34
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 35 0.34
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 35 0.34
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 35 0.34
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 35 0.34
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.34
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 35 0.34
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 35 0.34
AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens ... 31 3.2
AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protei... 31 4.2
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 5.6
X85133-1|CAA59445.1| 948|Homo sapiens RB protein binding protei... 30 9.8
AY072922-1|AAL68925.1| 1625|Homo sapiens p53-associated cellular... 30 9.8
AF352051-1|AAL05625.1| 1616|Homo sapiens proliferation potential... 30 9.8
AB112075-1|BAC77637.1| 1758|Homo sapiens retinoblastoma binding ... 30 9.8
AB112074-1|BAC77636.1| 1792|Homo sapiens retinoblastoma binding ... 30 9.8
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/83 (59%), Positives = 58/83 (69%), Gaps = 11/83 (13%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 659
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 660 FAEAVSEPGLAFVAAKFDGILGM 728
F EA +PG+ F+AAKFDGILGM
Sbjct: 179 FGEATKQPGITFIAAKFDGILGM 201
Score = 92.7 bits (220), Expect = 1e-18
Identities = 50/94 (53%), Positives = 57/94 (60%), Gaps = 11/94 (11%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYGV 405
R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 23 RIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGE 82
Query: 406 ISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIA 507
I IGTPPQ F VVFDTGSSNLWVPS C +IA
Sbjct: 83 IGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIA 116
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/83 (59%), Positives = 58/83 (69%), Gaps = 11/83 (13%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 659
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 660 FAEAVSEPGLAFVAAKFDGILGM 728
F EA +PG+ F+AAKFDGILGM
Sbjct: 179 FGEATKQPGITFIAAKFDGILGM 201
Score = 92.7 bits (220), Expect = 1e-18
Identities = 50/94 (53%), Positives = 57/94 (60%), Gaps = 11/94 (11%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYGV 405
R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 23 RIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGE 82
Query: 406 ISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIA 507
I IGTPPQ F VVFDTGSSNLWVPS C +IA
Sbjct: 83 IGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIA 116
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/83 (59%), Positives = 58/83 (69%), Gaps = 11/83 (13%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 659
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 660 FAEAVSEPGLAFVAAKFDGILGM 728
F EA +PG+ F+AAKFDGILGM
Sbjct: 179 FGEATKQPGITFIAAKFDGILGM 201
Score = 92.7 bits (220), Expect = 1e-18
Identities = 50/94 (53%), Positives = 57/94 (60%), Gaps = 11/94 (11%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYGV 405
R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 23 RIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGE 82
Query: 406 ISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIA 507
I IGTPPQ F VVFDTGSSNLWVPS C +IA
Sbjct: 83 IGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIA 116
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/83 (59%), Positives = 58/83 (69%), Gaps = 11/83 (13%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 659
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 660 FAEAVSEPGLAFVAAKFDGILGM 728
F EA +PG+ F+AAKFDGILGM
Sbjct: 179 FGEATKQPGITFIAAKFDGILGM 201
Score = 92.7 bits (220), Expect = 1e-18
Identities = 50/94 (53%), Positives = 57/94 (60%), Gaps = 11/94 (11%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYGV 405
R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 23 RIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGE 82
Query: 406 ISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIA 507
I IGTPPQ F VVFDTGSSNLWVPS C +IA
Sbjct: 83 IGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIA 116
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/83 (59%), Positives = 58/83 (69%), Gaps = 11/83 (13%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 659
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 660 FAEAVSEPGLAFVAAKFDGILGM 728
F EA +PG+ F+AAKFDGILGM
Sbjct: 179 FGEATKQPGITFIAAKFDGILGM 201
Score = 92.7 bits (220), Expect = 1e-18
Identities = 50/94 (53%), Positives = 57/94 (60%), Gaps = 11/94 (11%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYGV 405
R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 23 RIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGE 82
Query: 406 ISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIA 507
I IGTPPQ F VVFDTGSSNLWVPS C +IA
Sbjct: 83 IGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIA 116
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/83 (59%), Positives = 58/83 (69%), Gaps = 11/83 (13%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 659
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 660 FAEAVSEPGLAFVAAKFDGILGM 728
F EA +PG+ F+AAKFDGILGM
Sbjct: 179 FGEATKQPGITFIAAKFDGILGM 201
Score = 92.7 bits (220), Expect = 1e-18
Identities = 50/94 (53%), Positives = 57/94 (60%), Gaps = 11/94 (11%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYGV 405
R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 23 RIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGE 82
Query: 406 ISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIA 507
I IGTPPQ F VVFDTGSSNLWVPS C +IA
Sbjct: 83 IGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIA 116
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/83 (59%), Positives = 58/83 (69%), Gaps = 11/83 (13%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 659
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 660 FAEAVSEPGLAFVAAKFDGILGM 728
F EA +PG+ F+AAKFDGILGM
Sbjct: 179 FGEATKQPGITFIAAKFDGILGM 201
Score = 92.7 bits (220), Expect = 1e-18
Identities = 50/94 (53%), Positives = 57/94 (60%), Gaps = 11/94 (11%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYGV 405
R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 23 RIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGE 82
Query: 406 ISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIA 507
I IGTPPQ F VVFDTGSSNLWVPS C +IA
Sbjct: 83 IGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIA 116
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 86.6 bits (205), Expect = 8e-17
Identities = 42/87 (48%), Positives = 56/87 (64%), Gaps = 5/87 (5%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIGTP 423
R+PLHR++ R + + EL +L G P PLSNY D QY+G I +GTP
Sbjct: 28 RIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGTP 87
Query: 424 PQSFKVVFDTGSSNLWVPSKKCHYTNI 504
PQ+F V FDTGSSNLWVPS++CH+ ++
Sbjct: 88 PQNFTVAFDTGSSNLWVPSRRCHFFSV 114
Score = 82.6 bits (195), Expect = 1e-15
Identities = 36/72 (50%), Positives = 51/72 (70%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLA 692
LH+++D + S ++ ANGT+FAI+YG+G + G LS D +T+GG+K F EA+ EP L
Sbjct: 118 LHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLV 177
Query: 693 FVAAKFDGILGM 728
F A FDGILG+
Sbjct: 178 FAFAHFDGILGL 189
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 86.2 bits (204), Expect = 1e-16
Identities = 42/87 (48%), Positives = 56/87 (64%), Gaps = 5/87 (5%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIGTP 423
R+PLHR++ R + + EL +L G P PLSNY D QY+G I +GTP
Sbjct: 28 RIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGTP 87
Query: 424 PQSFKVVFDTGSSNLWVPSKKCHYTNI 504
PQ+F V FDTGSSNLWVPS++CH+ ++
Sbjct: 88 PQNFTVAFDTGSSNLWVPSRRCHFFSV 114
Score = 82.6 bits (195), Expect = 1e-15
Identities = 36/72 (50%), Positives = 51/72 (70%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLA 692
LH+++D + S ++ ANGT+FAI+YG+G + G LS D +T+GG+K F EA+ EP L
Sbjct: 118 LHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLV 177
Query: 693 FVAAKFDGILGM 728
F A FDGILG+
Sbjct: 178 FAFAHFDGILGL 189
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 86.2 bits (204), Expect = 1e-16
Identities = 42/87 (48%), Positives = 56/87 (64%), Gaps = 5/87 (5%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIGTP 423
R+PLHR++ R + + EL +L G P PLSNY D QY+G I +GTP
Sbjct: 28 RIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGTP 87
Query: 424 PQSFKVVFDTGSSNLWVPSKKCHYTNI 504
PQ+F V FDTGSSNLWVPS++CH+ ++
Sbjct: 88 PQNFTVAFDTGSSNLWVPSRRCHFFSV 114
Score = 82.6 bits (195), Expect = 1e-15
Identities = 36/72 (50%), Positives = 51/72 (70%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLA 692
LH+++D + S ++ ANGT+FAI+YG+G + G LS D +T+GG+K F EA+ EP L
Sbjct: 118 LHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLV 177
Query: 693 FVAAKFDGILGM 728
F A FDGILG+
Sbjct: 178 FAFAHFDGILGL 189
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 86.2 bits (204), Expect = 1e-16
Identities = 42/87 (48%), Positives = 56/87 (64%), Gaps = 5/87 (5%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIGTP 423
R+PLHR++ R + + EL +L G P PLSNY D QY+G I +GTP
Sbjct: 28 RIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGTP 87
Query: 424 PQSFKVVFDTGSSNLWVPSKKCHYTNI 504
PQ+F V FDTGSSNLWVPS++CH+ ++
Sbjct: 88 PQNFTVAFDTGSSNLWVPSRRCHFFSV 114
Score = 82.6 bits (195), Expect = 1e-15
Identities = 36/72 (50%), Positives = 51/72 (70%)
Frame = +3
Query: 513 LHNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLA 692
LH+++D + S ++ ANGT+FAI+YG+G + G LS D +T+GG+K F EA+ EP L
Sbjct: 118 LHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLV 177
Query: 693 FVAAKFDGILGM 728
F A FDGILG+
Sbjct: 178 FAFAHFDGILGL 189
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 84.6 bits (200), Expect = 3e-16
Identities = 41/87 (47%), Positives = 56/87 (64%), Gaps = 5/87 (5%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIGTP 423
R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +GTP
Sbjct: 24 RIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLGTP 83
Query: 424 PQSFKVVFDTGSSNLWVPSKKCHYTNI 504
PQ+F V FDTGSSNLWVPS++CH+ ++
Sbjct: 84 PQNFTVAFDTGSSNLWVPSRRCHFFSV 110
Score = 67.7 bits (158), Expect = 4e-11
Identities = 29/71 (40%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H++++ S ++ +GT+FAI+YG+G + G LS D +T+GG+K F EA+ E L F
Sbjct: 115 HHRFNPNASSSFKPSGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWESSLVF 174
Query: 696 VAAKFDGILGM 728
++ DGILG+
Sbjct: 175 TVSRPDGILGL 185
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 84.6 bits (200), Expect = 3e-16
Identities = 41/87 (47%), Positives = 56/87 (64%), Gaps = 5/87 (5%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIGTP 423
R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +GTP
Sbjct: 28 RIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLGTP 87
Query: 424 PQSFKVVFDTGSSNLWVPSKKCHYTNI 504
PQ+F V FDTGSSNLWVPS++CH+ ++
Sbjct: 88 PQNFTVAFDTGSSNLWVPSRRCHFFSV 114
Score = 67.7 bits (158), Expect = 4e-11
Identities = 29/71 (40%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H++++ S ++ +GT+FAI+YG+G + G LS D +T+GG+K F EA+ E L F
Sbjct: 119 HHRFNPNASSSFKPSGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWESSLVF 178
Query: 696 VAAKFDGILGM 728
++ DGILG+
Sbjct: 179 TVSRPDGILGL 189
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/71 (50%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H+++ +S TY G F+I+YG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 696 VAAKFDGILGM 728
V A+FDGILG+
Sbjct: 177 VDAEFDGILGL 187
Score = 75.4 bits (177), Expect = 2e-13
Identities = 31/42 (73%), Positives = 36/42 (85%)
Frame = +1
Query: 364 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/71 (50%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H+++ +S TY G F+I+YG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 696 VAAKFDGILGM 728
V A+FDGILG+
Sbjct: 177 VDAEFDGILGL 187
Score = 75.4 bits (177), Expect = 2e-13
Identities = 31/42 (73%), Positives = 36/42 (85%)
Frame = +1
Query: 364 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/71 (50%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H+++ +S TY G F+I+YG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 696 VAAKFDGILGM 728
V A+FDGILG+
Sbjct: 177 VDAEFDGILGL 187
Score = 75.4 bits (177), Expect = 2e-13
Identities = 31/42 (73%), Positives = 36/42 (85%)
Frame = +1
Query: 364 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/71 (50%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H+++ +S TY G F+I+YG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 696 VAAKFDGILGM 728
V A+FDGILG+
Sbjct: 177 VDAEFDGILGL 187
Score = 75.4 bits (177), Expect = 2e-13
Identities = 31/42 (73%), Positives = 36/42 (85%)
Frame = +1
Query: 364 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/71 (50%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H+++ +S TY G F+I+YG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 696 VAAKFDGILGM 728
V A+FDGILG+
Sbjct: 177 VDAEFDGILGL 187
Score = 75.4 bits (177), Expect = 2e-13
Identities = 31/42 (73%), Positives = 36/42 (85%)
Frame = +1
Query: 364 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/71 (50%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H+++ +S TY G F+I+YG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 696 VAAKFDGILGM 728
V A+FDGILG+
Sbjct: 177 VDAEFDGILGL 187
Score = 75.4 bits (177), Expect = 2e-13
Identities = 31/42 (73%), Positives = 36/42 (85%)
Frame = +1
Query: 364 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/71 (50%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H+++ +S TY G F+I+YG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 696 VAAKFDGILGM 728
V A+FDGILG+
Sbjct: 177 VDAEFDGILGL 187
Score = 75.4 bits (177), Expect = 2e-13
Identities = 31/42 (73%), Positives = 36/42 (85%)
Frame = +1
Query: 364 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAQFDGVVGM 196
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAEFDGVVGM 196
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAEFDGVVGM 196
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAEFDGVVGM 196
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAEFDGVVGM 196
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAEFDGVVGM 196
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAEFDGVVGM 196
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAEFDGVVGM 196
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 78.6 bits (185), Expect = 2e-14
Identities = 32/40 (80%), Positives = 36/40 (90%)
Frame = +1
Query: 370 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 186 MLAEFDGVVGM 196
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 74.9 bits (176), Expect = 3e-13
Identities = 43/90 (47%), Positives = 51/90 (56%), Gaps = 12/90 (13%)
Frame = +1
Query: 256 YRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP-----EPLSNYLDAQYY 399
Y+VPL R K+ R E G + L+ KY +P +PL NYLD +Y+
Sbjct: 18 YKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEYF 77
Query: 400 GVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
G I IGTP Q F VVFDTGSSNLWVPS C
Sbjct: 78 GTIGIGTPAQDFTVVFDTGSSNLWVPSVYC 107
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/71 (40%), Positives = 41/71 (57%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
HN+++ S TY + +I YG+GS++G L D V VGG+ Q F + +EPG
Sbjct: 115 HNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFL 174
Query: 696 VAAKFDGILGM 728
A FDGILG+
Sbjct: 175 YYAPFDGILGL 185
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 74.9 bits (176), Expect = 3e-13
Identities = 43/90 (47%), Positives = 51/90 (56%), Gaps = 12/90 (13%)
Frame = +1
Query: 256 YRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP-----EPLSNYLDAQYY 399
Y+VPL R K+ R E G + L+ KY +P +PL NYLD +Y+
Sbjct: 18 YKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEYF 77
Query: 400 GVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
G I IGTP Q F VVFDTGSSNLWVPS C
Sbjct: 78 GTIGIGTPAQDFTVVFDTGSSNLWVPSVYC 107
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/71 (40%), Positives = 41/71 (57%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
HN+++ S TY + +I YG+GS++G L D V VGG+ Q F + +EPG
Sbjct: 115 HNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFL 174
Query: 696 VAAKFDGILGM 728
A FDGILG+
Sbjct: 175 YYAPFDGILGL 185
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 74.5 bits (175), Expect = 3e-13
Identities = 44/92 (47%), Positives = 54/92 (58%), Gaps = 9/92 (9%)
Frame = +1
Query: 241 LRNGTYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 393
L +VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
Score = 74.5 bits (175), Expect = 3e-13
Identities = 32/71 (45%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H++++ +S TY NG F+++YGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 696 VAAKFDGILGM 728
V A+FDGI+G+
Sbjct: 172 VYAQFDGIMGL 182
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 74.5 bits (175), Expect = 3e-13
Identities = 44/92 (47%), Positives = 54/92 (58%), Gaps = 9/92 (9%)
Frame = +1
Query: 241 LRNGTYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 393
L +VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
Score = 74.5 bits (175), Expect = 3e-13
Identities = 32/71 (45%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H++++ +S TY NG F+++YGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 696 VAAKFDGILGM 728
V A+FDGI+G+
Sbjct: 172 VYAQFDGIMGL 182
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 74.5 bits (175), Expect = 3e-13
Identities = 44/92 (47%), Positives = 54/92 (58%), Gaps = 9/92 (9%)
Frame = +1
Query: 241 LRNGTYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 393
L +VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 11 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 69
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 70 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 101
Score = 74.5 bits (175), Expect = 3e-13
Identities = 32/71 (45%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H++++ +S TY NG F+++YGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 109 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 168
Query: 696 VAAKFDGILGM 728
V A+FDGI+G+
Sbjct: 169 VYAQFDGIMGL 179
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 74.5 bits (175), Expect = 3e-13
Identities = 44/92 (47%), Positives = 54/92 (58%), Gaps = 9/92 (9%)
Frame = +1
Query: 241 LRNGTYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 393
L +VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
Score = 74.5 bits (175), Expect = 3e-13
Identities = 32/71 (45%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H++++ +S TY NG F+++YGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 696 VAAKFDGILGM 728
V A+FDGI+G+
Sbjct: 172 VYAQFDGIMGL 182
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 74.5 bits (175), Expect = 3e-13
Identities = 44/92 (47%), Positives = 54/92 (58%), Gaps = 9/92 (9%)
Frame = +1
Query: 241 LRNGTYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 393
L +VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
Score = 74.5 bits (175), Expect = 3e-13
Identities = 32/71 (45%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H++++ +S TY NG F+++YGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 696 VAAKFDGILGM 728
V A+FDGI+G+
Sbjct: 172 VYAQFDGIMGL 182
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 74.5 bits (175), Expect = 3e-13
Identities = 44/92 (47%), Positives = 54/92 (58%), Gaps = 9/92 (9%)
Frame = +1
Query: 241 LRNGTYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 393
L +VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
Score = 74.5 bits (175), Expect = 3e-13
Identities = 32/71 (45%), Positives = 49/71 (69%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H++++ +S TY NG F+++YGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 696 VAAKFDGILGM 728
V A+FDGI+G+
Sbjct: 172 VYAQFDGIMGL 182
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 73.3 bits (172), Expect = 8e-13
Identities = 42/90 (46%), Positives = 51/90 (56%), Gaps = 12/90 (13%)
Frame = +1
Query: 256 YRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP-----EPLSNYLDAQYY 399
Y+VPL R K+ R E G + L+ KY +P +PL NYLD +Y+
Sbjct: 18 YKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLVDEQPLENYLDMEYF 77
Query: 400 GVISIGTPPQSFKVVFDTGSSNLWVPSKKC 489
G I IGTP Q F V+FDTGSSNLWVPS C
Sbjct: 78 GTIGIGTPAQDFTVLFDTGSSNLWVPSVYC 107
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/71 (40%), Positives = 41/71 (57%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
HN+++ S TY + +I YG+GS++G L D V VGG+ Q F + +EPG
Sbjct: 115 HNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFL 174
Query: 696 VAAKFDGILGM 728
A FDGILG+
Sbjct: 175 YYAPFDGILGL 185
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +3
Query: 516 HNKYDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 695
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 20 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 78
Query: 696 VAAKFDGILGM 728
+ A+FDG++GM
Sbjct: 79 MLAEFDGVVGM 89
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/85 (44%), Positives = 48/85 (56%), Gaps = 9/85 (10%)
Frame = +1
Query: 241 LRNGTYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 393
L +VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNL 468
Y+G ISIGTPPQ+F V+FDTGSS L
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSPL 97
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 38.3 bits (85), Expect = 0.028
Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E G F+
Sbjct: 35 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESGNFFLP 94
Query: 699 AAKFDGILGM 728
+++GILG+
Sbjct: 95 GIQWNGILGL 104
Score = 33.5 bits (73), Expect = 0.79
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = +1
Query: 412 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
IGTPPQ +++ DTGSSN V Y + F
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 35
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 37.5 bits (83), Expect = 0.049
Identities = 27/64 (42%), Positives = 34/64 (53%), Gaps = 9/64 (14%)
Frame = +1
Query: 259 RVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYGVIS 411
RVPL + K+ R E G E LR KYD + EP++ Y+DA Y+G IS
Sbjct: 24 RVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFGEIS 82
Query: 412 IGTP 423
IGTP
Sbjct: 83 IGTP 86
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 27 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 86
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 87 GIKWNGILGL 96
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 51 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 110
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 111 GIKWNGILGL 120
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 51
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 36.7 bits (81), Expect = 0.085
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 525 YDSRKSKTYVANGTQFAIKYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV- 698
+D+ +S TY + G +KY GS +GF+ D VT+ G + E F+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLP 189
Query: 699 AAKFDGILGM 728
K++GILG+
Sbjct: 190 GIKWNGILGL 199
Score = 36.3 bits (80), Expect = 0.11
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAF 510
YY + IGTPPQ +++ DTGSSN V Y + F
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 35.1 bits (77), Expect = 0.26
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = +3
Query: 573 AIKYGSGSLS-GFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 728
A KY G LS + + V ++V Q F + +EPG FV A+FDGI+G+
Sbjct: 51 AWKYRFGDLSVTYEPMAYMDVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGL 103
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAV 88
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 394 YYGVISIGTPPQSFKVVFDTGSSNLWV 474
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAV 132
>AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens
cDNA FLJ30579 fis, clone BRAWH2006989, weakly similar to
DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (EC
2.7.7.6). ).
Length = 260
Score = 31.5 bits (68), Expect = 3.2
Identities = 17/35 (48%), Positives = 18/35 (51%)
Frame = -2
Query: 624 HHQWRGSRRGCRSRTLSRTGCHSRRTSWTCGCRTC 520
H+ W GS R C S T S G HS SWT R C
Sbjct: 26 HNSWTGSNRACSSWTGSTRG-HS---SWTGSSRAC 56
>AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protein
LIP8 protein.
Length = 119
Score = 31.1 bits (67), Expect = 4.2
Identities = 12/33 (36%), Positives = 16/33 (48%)
Frame = -2
Query: 615 WRGSRRGCRSRTLSRTGCHSRRTSWTCGCRTCC 517
W GS+R C + + + S SW CR CC
Sbjct: 8 WPGSKRECANCRVGTSSWRSSGWSWWKDCRPCC 40
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 5.6
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -2
Query: 459 GSGVEYHLERLRRRADTDHSVVLSIK 382
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>X85133-1|CAA59445.1| 948|Homo sapiens RB protein binding protein
protein.
Length = 948
Score = 29.9 bits (64), Expect = 9.8
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -1
Query: 724 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 587
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 429 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 474
>AY072922-1|AAL68925.1| 1625|Homo sapiens p53-associated cellular
protein PACT protein.
Length = 1625
Score = 29.9 bits (64), Expect = 9.8
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -1
Query: 724 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 587
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 472 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 517
>AF352051-1|AAL05625.1| 1616|Homo sapiens proliferation
potential-related protein protein.
Length = 1616
Score = 29.9 bits (64), Expect = 9.8
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -1
Query: 724 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 587
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 429 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 474
>AB112075-1|BAC77637.1| 1758|Homo sapiens retinoblastoma binding
protein 6 isoform 2 protein.
Length = 1758
Score = 29.9 bits (64), Expect = 9.8
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -1
Query: 724 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 587
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 650
>AB112074-1|BAC77636.1| 1792|Homo sapiens retinoblastoma binding
protein 6 isoform 1 protein.
Length = 1792
Score = 29.9 bits (64), Expect = 9.8
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -1
Query: 724 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 587
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 650
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,704,734
Number of Sequences: 237096
Number of extensions: 2395732
Number of successful extensions: 6597
Number of sequences better than 10.0: 78
Number of HSP's better than 10.0 without gapping: 6026
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6573
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8623170556
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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