Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV30215
(677 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P34896 Cluster: Serine hydroxymethyltransferase, cytoso... 91 3e-17
UniRef50_Q5BJF5 Cluster: Serine hydroxymethyltransferase; n=3; E... 90 5e-17
UniRef50_P34897 Cluster: Serine hydroxymethyltransferase, mitoch... 90 5e-17
UniRef50_A4SBB9 Cluster: Serine hydroxymethyltransferase; n=11; ... 84 3e-15
UniRef50_Q5C0V4 Cluster: SJCHGC07535 protein; n=1; Schistosoma j... 83 5e-15
UniRef50_UPI0000E49DF3 Cluster: PREDICTED: similar to serine hyd... 80 4e-14
UniRef50_A6MJY3 Cluster: Mitochondrial serine hydroxymethyltrans... 67 4e-10
UniRef50_O62585 Cluster: Serine hydroxymethyltransferase, cytoso... 65 1e-09
UniRef50_Q9U638 Cluster: SHMT; n=5; Aconoidasida|Rep: SHMT - Pla... 65 2e-09
UniRef50_Q9A8J6 Cluster: Serine hydroxymethyltransferase; n=42; ... 64 2e-09
UniRef50_Q6LHN7 Cluster: Serine hydroxymethyltransferase 2; n=27... 64 2e-09
UniRef50_Q9LM59 Cluster: Serine hydroxymethyltransferase; n=21; ... 62 9e-09
UniRef50_O23984 Cluster: Expressed sequence tag; n=7; Poaceae|Re... 62 1e-08
UniRef50_Q7RQX7 Cluster: Serine hydroxymethyltransferase; n=4; P... 61 3e-08
UniRef50_Q5CM80 Cluster: Serine hydroxymethyltransferase; n=2; C... 61 3e-08
UniRef50_O83349 Cluster: Serine hydroxymethyltransferase; n=18; ... 61 3e-08
UniRef50_Q72IH2 Cluster: Serine hydroxymethyltransferase; n=6; B... 61 3e-08
UniRef50_A2EAE3 Cluster: Serine hydroxymethyltransferase; n=1; T... 59 8e-08
UniRef50_Q183S3 Cluster: Serine hydroxymethyltransferase; n=1; C... 59 1e-07
UniRef50_Q2GRC5 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-07
UniRef50_Q6G3L3 Cluster: Serine hydroxymethyltransferase; n=163;... 57 5e-07
UniRef50_A7D249 Cluster: Glycine hydroxymethyltransferase; n=1; ... 56 8e-07
UniRef50_Q11NZ7 Cluster: Serine hydroxymethyltransferase; n=6; B... 56 1e-06
UniRef50_Q9HPY5 Cluster: Serine hydroxymethyltransferase; n=79; ... 55 1e-06
UniRef50_Q9RYB2 Cluster: Serine hydroxymethyltransferase; n=43; ... 54 4e-06
UniRef50_A6PKY7 Cluster: Serine hydroxymethyltransferase; n=2; B... 53 6e-06
UniRef50_Q89HS7 Cluster: Serine hydroxymethyltransferase; n=2; R... 53 7e-06
UniRef50_Q9PJW0 Cluster: Serine hydroxymethyltransferase; n=8; C... 52 1e-05
UniRef50_Q8KC36 Cluster: Serine hydroxymethyltransferase; n=103;... 52 1e-05
UniRef50_Q98A81 Cluster: Serine hydroxymethyltransferase 2; n=4;... 52 2e-05
UniRef50_Q62I16 Cluster: Serine hydroxymethyltransferase 1; n=45... 48 2e-04
UniRef50_Q8FQR1 Cluster: Serine hydroxymethyltransferase; n=37; ... 48 3e-04
UniRef50_Q8EWD1 Cluster: Serine hydroxymethyltransferase; n=14; ... 46 8e-04
UniRef50_Q057P9 Cluster: Serine hydroxymethyltransferase; n=3; G... 46 0.001
UniRef50_Q7XZ78 Cluster: Hydromethyl transferase; n=1; Griffiths... 44 0.003
UniRef50_Q12RK5 Cluster: Glycine hydroxymethyltransferase; n=2; ... 43 0.006
UniRef50_A0CF19 Cluster: Chromosome undetermined scaffold_174, w... 43 0.006
UniRef50_O29406 Cluster: Serine hydroxymethyltransferase; n=6; E... 42 0.010
UniRef50_Q8ZYF9 Cluster: Serine hydroxymethyltransferase; n=5; T... 40 0.056
UniRef50_Q23KJ4 Cluster: Serine hydroxymethyltransferase family ... 39 0.097
UniRef50_Q9HI38 Cluster: Serine hydroxymethyltransferase; n=5; T... 37 0.39
UniRef50_A0D4A6 Cluster: Chromosome undetermined scaffold_37, wh... 37 0.52
UniRef50_Q2R3T6 Cluster: Expressed protein; n=6; Oryza sativa|Re... 35 1.6
UniRef50_A2E8Z5 Cluster: Viral A-type inclusion protein, putativ... 35 1.6
UniRef50_Q2FQJ9 Cluster: Methyl-accepting chemotaxis sensory tra... 35 1.6
UniRef50_A2DDP2 Cluster: Viral A-type inclusion protein, putativ... 34 2.8
UniRef50_A0RQ55 Cluster: Putative uncharacterized protein; n=1; ... 34 3.7
UniRef50_Q23DL9 Cluster: TBC domain containing protein; n=1; Tet... 34 3.7
UniRef50_Q4RSG4 Cluster: Chromosome 13 SCAF15000, whole genome s... 33 4.8
UniRef50_Q6YQM5 Cluster: Chromosome segregation ATPase homolog; ... 33 6.4
UniRef50_Q54DX0 Cluster: Putative uncharacterized protein; n=1; ... 33 6.4
UniRef50_A2DKA7 Cluster: C-myc binding protein, putative; n=1; T... 33 6.4
UniRef50_Q28KQ5 Cluster: TRAP dicarboxylate transporter-DctP sub... 33 8.4
UniRef50_Q0S584 Cluster: Monooxygenase; n=2; Bacteria|Rep: Monoo... 33 8.4
UniRef50_Q45KZ0 Cluster: Structural maintenance of chromosome 2;... 33 8.4
UniRef50_A2FY63 Cluster: Putative uncharacterized protein; n=1; ... 33 8.4
UniRef50_Q9NZR2 Cluster: Low-density lipoprotein receptor-relate... 33 8.4
>UniRef50_P34896 Cluster: Serine hydroxymethyltransferase,
cytosolic; n=86; root|Rep: Serine
hydroxymethyltransferase, cytosolic - Homo sapiens
(Human)
Length = 483
Score = 90.6 bits (215), Expect = 3e-17
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 337 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 396
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 397 RPSGLRL 403
Score = 56.0 bits (129), Expect = 8e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 397 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 455
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 456 KYQAAVQALREEVESFASLFPLPGLPDF 483
>UniRef50_Q5BJF5 Cluster: Serine hydroxymethyltransferase; n=3;
Euarchontoglires|Rep: Serine hydroxymethyltransferase -
Homo sapiens (Human)
Length = 480
Score = 89.8 bits (213), Expect = 5e-17
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 332 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 391
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 392 RSAITPGGLRL 402
Score = 70.9 bits (166), Expect = 3e-11
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 405 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 463
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 464 RVEQFARAFPMPGFDEH 480
>UniRef50_P34897 Cluster: Serine hydroxymethyltransferase,
mitochondrial precursor; n=160; Eukaryota|Rep: Serine
hydroxymethyltransferase, mitochondrial precursor - Homo
sapiens (Human)
Length = 504
Score = 89.8 bits (213), Expect = 5e-17
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 356 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 415
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 416 RSAITPGGLRL 426
Score = 70.9 bits (166), Expect = 3e-11
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 429 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 487
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 488 RVEQFARAFPMPGFDEH 504
>UniRef50_A4SBB9 Cluster: Serine hydroxymethyltransferase; n=11;
Viridiplantae|Rep: Serine hydroxymethyltransferase -
Ostreococcus lucimarinus CCE9901
Length = 525
Score = 84.2 bits (199), Expect = 3e-15
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
A+ L+ G + +GGTD HLAL+DLR +G+ G+ ERVLEL +ACNKNTVPGD+ A+
Sbjct: 373 AMANRLVQHGIKLVSGGTDNHLALLDLRPMGVDGSRVERVLELAHIACNKNTVPGDVSAM 432
Query: 234 NPSGIRL 254
P G+R+
Sbjct: 433 VPGGLRI 439
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/78 (39%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRALKXGLEI-IKVSGLKLVDFNKAIEENAEFKKKIENL 433
TPALT+RG E D + V +FI R +K ++ K G KL DF A+ E+ E+ ++ L
Sbjct: 441 TPALTSRGFTEKDFEQVAEFIVRGIKIAQDVKSKSEGTKLKDFRAAL-ESKEW-PELTQL 498
Query: 434 KEEVENYSKSFPLPGFDK 487
++VE ++ FP GF+K
Sbjct: 499 TKDVEEFATQFPTIGFEK 516
>UniRef50_Q5C0V4 Cluster: SJCHGC07535 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07535 protein - Schistosoma
japonicum (Blood fluke)
Length = 218
Score = 83.4 bits (197), Expect = 5e-15
Identities = 36/70 (51%), Positives = 47/70 (67%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K LC+ L GY + TGG+D HL L+DLR + + GA AE++LEL +A NKNT PGD
Sbjct: 69 KNMKQLCKSLTDYGYELVTGGSDTHLCLIDLRPLKIDGARAEKILELVRIAANKNTCPGD 128
Query: 222 IGALNPSGIR 251
+ AL P G+R
Sbjct: 129 LSALRPGGLR 138
Score = 53.6 bits (123), Expect = 4e-06
Identities = 24/75 (32%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 263 ALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLV-DFNKAIEENAEFKKKIENLKE 439
ALT+R +E D V +FI ++ ++ +++ KL+ D+ +E N E + I L+
Sbjct: 143 ALTSRNFREKDFIKVAEFIHTGIQIAVKANELANSKLLKDYEVVVETNVEIRSMIGKLRR 202
Query: 440 EVENYSKSFPLPGFD 484
E+E ++ +PLPG D
Sbjct: 203 EIEEFASKYPLPGLD 217
>UniRef50_UPI0000E49DF3 Cluster: PREDICTED: similar to serine
hydroxymethyltransferase isoform 1; n=4; Coelomata|Rep:
PREDICTED: similar to serine hydroxymethyltransferase
isoform 1 - Strongylocentrotus purpuratus
Length = 496
Score = 80.2 bits (189), Expect = 4e-14
Identities = 37/67 (55%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
A+ E L+ RGY+I++GGTD HL L+DLR +GL GA E VLE + NKNT PGD AL
Sbjct: 350 AMAEELMKRGYTISSGGTDTHLLLLDLRPLGLDGARGEFVLERVGIVLNKNTCPGDKSAL 409
Query: 234 NPSGIRL 254
P G+R+
Sbjct: 410 KPGGLRI 416
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/77 (42%), Positives = 48/77 (62%), Gaps = 1/77 (1%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRALKXGLEIIK-VSGLKLVDFNKAIEENAEFKKKIENL 433
TPALT+R K D +VVD+IDR LK E K S L DF + +++F+ K+ L
Sbjct: 418 TPALTSRNFKVTDFMMVVDYIDRGLKLTAEANKKCSSTTLRDFKAYVTSDSDFQSKLAAL 477
Query: 434 KEEVENYSKSFPLPGFD 484
++EVE+++ FPLPG +
Sbjct: 478 EKEVESFAVRFPLPGHE 494
>UniRef50_A6MJY3 Cluster: Mitochondrial serine
hydroxymethyltransferase-like protein; n=5;
Euteleostomi|Rep: Mitochondrial serine
hydroxymethyltransferase-like protein - Callithrix
jacchus (Common marmoset)
Length = 122
Score = 66.9 bits (156), Expect = 4e-10
Identities = 30/76 (39%), Positives = 51/76 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GL++ K KL DF + +++E +++ +L++
Sbjct: 47 PALTSRQFREDDFRRVVDFIDEGVNIGLDV-KSKTAKLQDFKSFLLKDSETSQRLADLRQ 105
Query: 440 EVENYSKSFPLPGFDK 487
VE ++++FP+PGFD+
Sbjct: 106 RVEQFARAFPMPGFDE 121
Score = 60.1 bits (139), Expect = 5e-08
Identities = 29/44 (65%), Positives = 32/44 (72%)
Frame = +3
Query: 123 LVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGALNPSGIRL 254
LVDLR GL GA AERVLEL S+ NKNT PGD A+ P G+RL
Sbjct: 1 LVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRL 44
>UniRef50_O62585 Cluster: Serine hydroxymethyltransferase,
cytosolic; n=1; Encephalitozoon cuniculi|Rep: Serine
hydroxymethyltransferase, cytosolic - Encephalitozoon
cuniculi
Length = 460
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/66 (45%), Positives = 41/66 (62%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGALN 236
LC L S G I TGGTD H+ LVDLR G+ GA E + + ++ N+N + G+ L+
Sbjct: 319 LCSRLQSLGLDILTGGTDNHMLLVDLRSTGVDGAAVEHMCDALGISLNRNAIVGNSSPLS 378
Query: 237 PSGIRL 254
PSGIR+
Sbjct: 379 PSGIRV 384
>UniRef50_Q9U638 Cluster: SHMT; n=5; Aconoidasida|Rep: SHMT -
Plasmodium falciparum
Length = 442
Score = 64.9 bits (151), Expect = 2e-09
Identities = 28/67 (41%), Positives = 41/67 (61%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L+ R + T GTD HL +VDLR + G+ + ++A NKNT+P D+ +
Sbjct: 306 ALAECLLKRNLDLVTNGTDNHLIVVDLRKYNITGSKLQETCNAINIALNKNTIPSDVDCV 365
Query: 234 NPSGIRL 254
+PSGIR+
Sbjct: 366 SPSGIRI 372
Score = 56.8 bits (131), Expect = 5e-07
Identities = 30/71 (42%), Positives = 44/71 (61%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLK 436
TPALTTRG KE D++ + D + +A+ E+ + G KLVDF K + N KI+ LK
Sbjct: 374 TPALTTRGCKEKDMEFIADMLLKAILLTDELQQKYGKKLVDFKKGLVNN----PKIDELK 429
Query: 437 EEVENYSKSFP 469
+EV ++K+ P
Sbjct: 430 KEVVQWAKNLP 440
>UniRef50_Q9A8J6 Cluster: Serine hydroxymethyltransferase; n=42;
Bacteria|Rep: Serine hydroxymethyltransferase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 429
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/68 (51%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L+ G +I +GGTD HL LVDLR G+ G AE LE + CNKN VP D
Sbjct: 303 ALAEALLKSGVNIVSGGTDSHLMLVDLRPKGVTGRDAEHSLERAYMTCNKNGVPFDTAPF 362
Query: 234 N-PSGIRL 254
SGIRL
Sbjct: 363 TITSGIRL 370
>UniRef50_Q6LHN7 Cluster: Serine hydroxymethyltransferase 2; n=27;
Bacteria|Rep: Serine hydroxymethyltransferase 2 -
Photobacterium profundum (Photobacterium sp. (strain
SS9))
Length = 431
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/67 (52%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDI-GAL 233
L E L +RG I T GTD HL LVDLR GL+G AE LE + CNKN +P D +
Sbjct: 307 LAEVLQNRGCDIVTNGTDTHLMLVDLRPKGLKGNAAENALERAGITCNKNGIPFDTEKPM 366
Query: 234 NPSGIRL 254
SGIRL
Sbjct: 367 VTSGIRL 373
>UniRef50_Q9LM59 Cluster: Serine hydroxymethyltransferase; n=21;
Eukaryota|Rep: Serine hydroxymethyltransferase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 599
Score = 62.5 bits (145), Expect = 9e-09
Identities = 30/71 (42%), Positives = 41/71 (57%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K AL LISR + TGGTD HL L DL +GL G E+V E+C + NK + +
Sbjct: 455 KNAKALASALISRKCKLITGGTDNHLLLWDLTPLGLTGKVYEKVCEMCHITVNKVAIFSE 514
Query: 222 IGALNPSGIRL 254
G ++P G+R+
Sbjct: 515 NGVISPGGVRI 525
Score = 37.5 bits (83), Expect = 0.30
Identities = 23/76 (30%), Positives = 41/76 (53%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLK 436
+PA+T+RG E + + + DF+ RA + + G KL K ++ K+I +L+
Sbjct: 527 SPAMTSRGCLEPEFETMADFLYRAAQIASAAQREHG-KL---QKEPLKSIYHCKEIADLR 582
Query: 437 EEVENYSKSFPLPGFD 484
+VE ++ F +P FD
Sbjct: 583 NQVEAFATQFAMPAFD 598
>UniRef50_O23984 Cluster: Expressed sequence tag; n=7; Poaceae|Rep:
Expressed sequence tag - Hordeum vulgare (Barley)
Length = 111
Score = 62.1 bits (144), Expect = 1e-08
Identities = 33/74 (44%), Positives = 46/74 (62%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PA+T+RGL E D + + +F+ +A+ L I K G L DF+K + N K IENLK
Sbjct: 34 PAMTSRGLVEKDFEQIAEFLHQAVTICLNIQKEHGKLLKDFSKGLVNN----KDIENLKV 89
Query: 440 EVENYSKSFPLPGF 481
EVE ++ SF +PGF
Sbjct: 90 EVEKFALSFDMPGF 103
Score = 39.1 bits (87), Expect = 0.097
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 165 ERVLELCSVACNKNTVPGDIGALNPSGIRL 254
E++ +LCS+ NKN V GD AL+P G+R+
Sbjct: 2 EKMCDLCSITLNKNAVFGDSSALSPGGVRI 31
>UniRef50_Q7RQX7 Cluster: Serine hydroxymethyltransferase; n=4;
Plasmodium|Rep: Serine hydroxymethyltransferase -
Plasmodium yoelii yoelii
Length = 446
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/67 (38%), Positives = 41/67 (61%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL + LI+ + T GTD H+ L+DLR G+ G+ + V +++ NKNT+P D +
Sbjct: 310 ALAKFLINNNIDLVTNGTDNHIVLIDLRKYGITGSKLQEVCNTINISINKNTIPSDNDCV 369
Query: 234 NPSGIRL 254
+P+G RL
Sbjct: 370 SPNGARL 376
Score = 55.2 bits (127), Expect = 1e-06
Identities = 29/80 (36%), Positives = 44/80 (55%)
Frame = +2
Query: 236 PQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFK 415
P + TPA+TTRG KE D+ + D + +A+K + + G KLV+F K + N E
Sbjct: 371 PNGARLGTPAMTTRGAKENDMKFIADTLLKAIKIAASLQEKYGKKLVEFKKGLTNNPE-- 428
Query: 416 KKIENLKEEVENYSKSFPLP 475
++ LK+EV + FP P
Sbjct: 429 --LDALKKEVVQWVTQFPFP 446
>UniRef50_Q5CM80 Cluster: Serine hydroxymethyltransferase; n=2;
Cryptosporidium|Rep: Serine hydroxymethyltransferase -
Cryptosporidium hominis
Length = 445
Score = 60.9 bits (141), Expect = 3e-08
Identities = 27/66 (40%), Positives = 42/66 (63%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGALN 236
LC+ L G I T GTD H L+D R + + GA AE+ LE+C ++ +++++P D +N
Sbjct: 305 LCKLLEESGIKILTNGTDSHKILIDTRSLNISGAKAEKALEVCEISTSRSSLPCDGRTMN 364
Query: 237 PSGIRL 254
SG+RL
Sbjct: 365 CSGVRL 370
>UniRef50_O83349 Cluster: Serine hydroxymethyltransferase; n=18;
Bacteria|Rep: Serine hydroxymethyltransferase -
Treponema pallidum
Length = 574
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/68 (47%), Positives = 42/68 (61%), Gaps = 1/68 (1%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD-IGA 230
AL + I +G + TGGTD HL L+D+R GL G AER L C V N+N++P D GA
Sbjct: 352 ALADACIQQGMQLQTGGTDNHLLLLDVRPFGLTGRQAERALIDCGVTLNRNSLPFDPNGA 411
Query: 231 LNPSGIRL 254
SG+R+
Sbjct: 412 WLTSGLRI 419
>UniRef50_Q72IH2 Cluster: Serine hydroxymethyltransferase; n=6;
Bacteria|Rep: Serine hydroxymethyltransferase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 407
Score = 60.9 bits (141), Expect = 3e-08
Identities = 30/55 (54%), Positives = 33/55 (60%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
L E L RGY I TGGTD HL LVDLR GL G AE L+ + NKN +P D
Sbjct: 293 LAEALARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAIPFD 347
Score = 33.1 bits (72), Expect = 6.4
Identities = 14/28 (50%), Positives = 19/28 (67%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRALKXG 340
TPA+TTRG ++ +V + IDRAL G
Sbjct: 361 TPAITTRGFTPEEMPLVAELIDRALLEG 388
>UniRef50_A2EAE3 Cluster: Serine hydroxymethyltransferase; n=1;
Trichomonas vaginalis G3|Rep: Serine
hydroxymethyltransferase - Trichomonas vaginalis G3
Length = 451
Score = 59.3 bits (137), Expect = 8e-08
Identities = 30/76 (39%), Positives = 44/76 (57%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLK 436
+PA+T+RGL E D + +FI + +K EI SG KL DF K + N I +K
Sbjct: 379 SPAMTSRGLDENDFKKIAEFIVKGVKISKEIKSKSGKKLSDFKKLAKNN----DNIREIK 434
Query: 437 EEVENYSKSFPLPGFD 484
+ V +++ FPLPG+D
Sbjct: 435 KTVTSFASKFPLPGYD 450
Score = 57.2 bits (132), Expect = 3e-07
Identities = 27/59 (45%), Positives = 35/59 (59%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPG 218
K ALC+ L I +GGTD H+AL+DLR + GA E VL+ + NKNT+PG
Sbjct: 312 KNIKALCDYLQQNNIDIVSGGTDSHMALIDLRRYNVDGARVEFVLDQMGITTNKNTIPG 370
>UniRef50_Q183S3 Cluster: Serine hydroxymethyltransferase; n=1;
Clostridium difficile 630|Rep: Serine
hydroxymethyltransferase - Clostridium difficile (strain
630)
Length = 418
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/80 (38%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Frame = +3
Query: 18 RRISETGDKERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVAC 197
++I E L LIS G+SI +GGTD H+ +VDLR L G E+ LE +
Sbjct: 280 KKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEYVGITV 339
Query: 198 NKNTVPGD-IGALNPSGIRL 254
NKN +P D SG+R+
Sbjct: 340 NKNVIPDDPQSPFVTSGVRI 359
>UniRef50_Q2GRC5 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 176
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/68 (44%), Positives = 41/68 (60%)
Frame = +3
Query: 51 AALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGA 230
A L L+S+GY + TGGTD H+ L+D R + G E VL ++ N+N +PGD G
Sbjct: 25 ATLSRELLSKGYHLLTGGTDSHIMLLDHRKDRISGFEVESVLRQVNIIANQNPLPGDKG- 83
Query: 231 LNPSGIRL 254
L SG+RL
Sbjct: 84 LRFSGLRL 91
>UniRef50_Q6G3L3 Cluster: Serine hydroxymethyltransferase; n=163;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Bartonella henselae (Rochalimaea henselae)
Length = 437
Score = 56.8 bits (131), Expect = 5e-07
Identities = 31/67 (46%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGA-L 233
L + L S G+ I +GGTD HL LVDLR + G AE L + CNKN++P D+
Sbjct: 306 LAKTLQSNGFDIVSGGTDNHLLLVDLRSKKVTGKCAELALGRAHITCNKNSIPFDLETPF 365
Query: 234 NPSGIRL 254
SGIRL
Sbjct: 366 ITSGIRL 372
>UniRef50_A7D249 Cluster: Glycine hydroxymethyltransferase; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Glycine
hydroxymethyltransferase - Halorubrum lacusprofundi ATCC
49239
Length = 460
Score = 56.0 bits (129), Expect = 8e-07
Identities = 32/69 (46%), Positives = 39/69 (56%), Gaps = 3/69 (4%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRG--VGLRGAPAERVLELCSVACNKNTVPGDI-G 227
L E L G+S+ +GGTD HL LVDLR L G A L ++ N NTVPG+
Sbjct: 339 LAETLQDHGFSLVSGGTDNHLVLVDLRDSHPDLPGGDAADALAAANIVLNGNTVPGETRS 398
Query: 228 ALNPSGIRL 254
NPSGIR+
Sbjct: 399 PFNPSGIRV 407
>UniRef50_Q11NZ7 Cluster: Serine hydroxymethyltransferase; n=6;
Bacteria|Rep: Serine hydroxymethyltransferase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 431
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/60 (43%), Positives = 32/60 (53%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K + E + +GY I +GGTD HL L+DLR L G AE L + NKN VP D
Sbjct: 307 KNAQIMAEAFLKKGYDIISGGTDNHLMLIDLRSKNLTGKEAENALIRADITINKNMVPFD 366
>UniRef50_Q9HPY5 Cluster: Serine hydroxymethyltransferase; n=79;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Halobacterium salinarium (Halobacterium halobium)
Length = 415
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/71 (45%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Frame = +3
Query: 51 AALCEGLISRGYSIATGGTDVHLALVDLR--GVGLRGAPAERVLELCSVACNKNTVPGDI 224
A L E L G+S+ +GGTD HL LVDLR + G E LE + N NTVP +
Sbjct: 292 AVLGERLQEHGFSLVSGGTDTHLVLVDLRESHPDISGGDVEGELEDVGIVLNANTVPDET 351
Query: 225 -GALNPSGIRL 254
A +PSGIR+
Sbjct: 352 RSAFDPSGIRI 362
>UniRef50_Q9RYB2 Cluster: Serine hydroxymethyltransferase; n=43;
Bacteria|Rep: Serine hydroxymethyltransferase -
Deinococcus radiodurans
Length = 408
Score = 53.6 bits (123), Expect = 4e-06
Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K AL +GY + +GGTD HL L+DLR GL G A R+L+ + +K+T+P D
Sbjct: 292 KNAQALAGEFQQKGYRVVSGGTDNHLFLLDLRPQGLNGTKATRLLDANHITISKSTLPYD 351
Query: 222 I-GALNPSGIRL 254
L+ GIR+
Sbjct: 352 TEKILHGGGIRI 363
Score = 37.1 bits (82), Expect = 0.39
Identities = 17/26 (65%), Positives = 20/26 (76%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRALK 334
TPA+TTRG+ EA + V D IDRALK
Sbjct: 365 TPAVTTRGMTEAHMTQVADLIDRALK 390
>UniRef50_A6PKY7 Cluster: Serine hydroxymethyltransferase; n=2;
Bacteria|Rep: Serine hydroxymethyltransferase -
Victivallis vadensis ATCC BAA-548
Length = 572
Score = 53.2 bits (122), Expect = 6e-06
Identities = 24/57 (42%), Positives = 32/57 (56%)
Frame = +3
Query: 51 AALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
A L E L+ RG+ I +GGTD HL L+DLR G L++ + NKN +P D
Sbjct: 450 AKLAEELVKRGFRIVSGGTDNHLMLIDLRPKHATGKAVANALDIAHITANKNMIPFD 506
Score = 37.5 bits (83), Expect = 0.30
Identities = 16/26 (61%), Positives = 22/26 (84%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRALK 334
TPA+TTRGLKEA++ V DFI+R ++
Sbjct: 520 TPAITTRGLKEAEMVRVADFIERGVE 545
>UniRef50_Q89HS7 Cluster: Serine hydroxymethyltransferase; n=2;
Rhizobiales|Rep: Serine hydroxymethyltransferase -
Bradyrhizobium japonicum
Length = 460
Score = 52.8 bits (121), Expect = 7e-06
Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 2/68 (2%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRG-VGLRGAPAERVLELCSVACNKNTVPGD-IGA 230
L L+ RG + T GTD H+ +VD VGL G AE VL+ ++ NK +P D
Sbjct: 329 LAGALMERGMKLVTDGTDNHMMVVDTAASVGLDGRAAEDVLDAIAITTNKQVIPDDPRPP 388
Query: 231 LNPSGIRL 254
L PSGIRL
Sbjct: 389 LRPSGIRL 396
>UniRef50_Q9PJW0 Cluster: Serine hydroxymethyltransferase; n=8;
Chlamydiaceae|Rep: Serine hydroxymethyltransferase -
Chlamydia muridarum
Length = 497
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDI-GAL 233
L E G + TGGTD H+ ++DL +G+ G AE +L +A N+N++P D G
Sbjct: 354 LAEIFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSVGIAVNRNSIPSDASGQW 413
Query: 234 NPSGIRL 254
SGIRL
Sbjct: 414 KTSGIRL 420
>UniRef50_Q8KC36 Cluster: Serine hydroxymethyltransferase; n=103;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Chlorobium tepidum
Length = 440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +3
Query: 51 AALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVP-GDIG 227
AA+ ++ GY I +GGT HL L+DLR + G AE +L + NKN VP D
Sbjct: 311 AAMAAKFLAAGYHIVSGGTKNHLMLLDLRNKNVNGKVAENLLHEAGITVNKNMVPFDDKS 370
Query: 228 ALNPSGIRL 254
SGIR+
Sbjct: 371 PFVTSGIRI 379
Score = 36.3 bits (80), Expect = 0.69
Identities = 14/25 (56%), Positives = 21/25 (84%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRAL 331
TPA+TTRG+K A+ + +V+FIDR +
Sbjct: 381 TPAMTTRGMKVAEAEKIVEFIDRVI 405
>UniRef50_Q98A81 Cluster: Serine hydroxymethyltransferase 2; n=4;
Bacteria|Rep: Serine hydroxymethyltransferase 2 -
Rhizobium loti (Mesorhizobium loti)
Length = 437
Score = 51.6 bits (118), Expect = 2e-05
Identities = 34/73 (46%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRG-APAERVLELCSVACNKNTVPG 218
K AL E L+ RGY + TGGTD H+ ++DLR L G A AER L + N + VPG
Sbjct: 309 KNAKALAEALLGRGYYLVTGGTDNHMLILDLRDRPLSGKAYAER-LARAGIITNFDMVPG 367
Query: 219 D-IGALNPSGIRL 254
D SGIRL
Sbjct: 368 DPRDPTVTSGIRL 380
>UniRef50_Q62I16 Cluster: Serine hydroxymethyltransferase 1; n=454;
root|Rep: Serine hydroxymethyltransferase 1 -
Burkholderia mallei (Pseudomonas mallei)
Length = 415
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/67 (38%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Frame = +3
Query: 57 LCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD-IGAL 233
L + L+ RG I +G T+ H+ LVDLR + G AE L + NKN +P D
Sbjct: 296 LAQTLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNAHITVNKNAIPNDPEKPF 355
Query: 234 NPSGIRL 254
SG+RL
Sbjct: 356 VTSGVRL 362
>UniRef50_Q8FQR1 Cluster: Serine hydroxymethyltransferase; n=37;
Bacteria|Rep: Serine hydroxymethyltransferase -
Corynebacterium efficiens
Length = 434
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/47 (46%), Positives = 27/47 (57%)
Frame = +3
Query: 81 GYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
G + TGGTDVHL L DLR + G AE +L + N+N VP D
Sbjct: 316 GIDVLTGGTDVHLVLADLRNSEMDGQQAEDLLHEVGITVNRNAVPFD 362
>UniRef50_Q8EWD1 Cluster: Serine hydroxymethyltransferase; n=14;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Mycoplasma penetrans
Length = 412
Score = 46.0 bits (104), Expect = 8e-04
Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Frame = +3
Query: 51 AALCEGLISRGYSIATGGTDVHLALVDL-RGVGLRGAPAERVLELCSVACNKNTVPGDI- 224
A L + L GY I G+D HL VDL + G E+ LE + NKN +P DI
Sbjct: 286 AILSQTLKELGYKIIADGSDNHLLSVDLYSSKQITGDLVEQWLEQAKIVVNKNLIPYDIN 345
Query: 225 GALNPSGIRL 254
A +PSGIR+
Sbjct: 346 SAKSPSGIRI 355
>UniRef50_Q057P9 Cluster: Serine hydroxymethyltransferase; n=3;
Gammaproteobacteria|Rep: Serine hydroxymethyltransferase
- Buchnera aphidicola subsp. Cinara cedri
Length = 417
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Frame = +3
Query: 72 ISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDI-GALNPSGI 248
+ R +S+ +G T+ HL L+DL + G A +L L + NKNT+P D SGI
Sbjct: 301 LKRNFSVISGKTNNHLFLIDLSEKKISGKEASNILALARIIVNKNTIPNDSQSPYITSGI 360
Query: 249 RL 254
R+
Sbjct: 361 RI 362
>UniRef50_Q7XZ78 Cluster: Hydromethyl transferase; n=1; Griffithsia
japonica|Rep: Hydromethyl transferase - Griffithsia
japonica (Red alga)
Length = 100
Score = 44.4 bits (100), Expect = 0.003
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDR--ALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIEN 430
T A+TTRG + D + +++DR A+ ++ G K+V F +A++ A I
Sbjct: 17 THAMTTRGCESGDFKAIAEYLDRGIAIASKVKADLGPGSKIVAFREALDSGAS-GSDIAA 75
Query: 431 LKEEVENYSKSFPLPGFDK 487
LK+EVE ++ F GFD+
Sbjct: 76 LKQEVEEFALRFEPIGFDR 94
>UniRef50_Q12RK5 Cluster: Glycine hydroxymethyltransferase; n=2;
Gammaproteobacteria|Rep: Glycine
hydroxymethyltransferase - Shewanella denitrificans
(strain OS217 / ATCC BAA-1090 / DSM 15013)
Length = 451
Score = 43.2 bits (97), Expect = 0.006
Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 78 RGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDI-GALNPSGIRL 254
+ Y + ++ H L+ LRG L GA AE LE C + NKN VPG+ A SG+R+
Sbjct: 327 KDYEVVGRKSENHTVLIRLRG-DLTGAIAESALEKCGIIVNKNRVPGETRSAFVTSGLRI 385
>UniRef50_A0CF19 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 439
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = +3
Query: 81 GYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
G+ + GGT+ HL LVDLR + E +L ++ CNK VP D
Sbjct: 317 GFDLIAGGTENHLILVDLRKFNVDAVKMEYILSQINIQCNKQLVPFD 363
>UniRef50_O29406 Cluster: Serine hydroxymethyltransferase; n=6;
Euryarchaeota|Rep: Serine hydroxymethyltransferase -
Archaeoglobus fulgidus
Length = 438
Score = 42.3 bits (95), Expect = 0.010
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Frame = +3
Query: 54 ALCEGLISRGYSIA---TGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDI 224
AL E L S GY + G T+ H VD+R G G +VLE + NKN +P D
Sbjct: 303 ALAEELYSLGYKVLGEKRGFTETHQVAVDVREFG-GGERVAKVLENAGIILNKNLLPWDS 361
Query: 225 --GALNPSGIRL 254
NPSGIR+
Sbjct: 362 LEKTANPSGIRI 373
>UniRef50_Q8ZYF9 Cluster: Serine hydroxymethyltransferase; n=5;
Thermoproteaceae|Rep: Serine hydroxymethyltransferase -
Pyrobaculum aerophilum
Length = 430
Score = 39.9 bits (89), Expect = 0.056
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +3
Query: 54 ALCEGLISRGYSIA---TGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDI 224
AL E L G + G T H VD+ G G R+LE ++ NKN +P D
Sbjct: 292 ALAEALAEEGVTPVGERLGYTKTHQVAVDVSKFG-GGDKVARLLEEANIIVNKNALPWDK 350
Query: 225 GALNPSGIRL 254
L PSGIR+
Sbjct: 351 SVLKPSGIRM 360
>UniRef50_Q23KJ4 Cluster: Serine hydroxymethyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep: Serine
hydroxymethyltransferase family protein - Tetrahymena
thermophila SB210
Length = 515
Score = 39.1 bits (87), Expect = 0.097
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +2
Query: 257 TPALTTRGLKEADIDIVVDFIDRA--LKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIEN 430
T +TTRG E D + +FIDR L L + + + K E+N + ++
Sbjct: 439 THPMTTRGCTENDFKTIAEFIDRGALLLKELSTKQPAPTSAQEIQKWAEQNVQSNSSLQK 498
Query: 431 LKEEVENYSKSFPLP 475
L++E ++ K F +P
Sbjct: 499 LQQEAASFVKQFEVP 513
Score = 36.7 bits (81), Expect = 0.52
Identities = 18/58 (31%), Positives = 29/58 (50%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVP 215
K AL + + Y+I T GT+ HL LVD + G+ +LE + ++T+P
Sbjct: 367 KNAQALFQSFSQKQYNILTNGTENHLVLVDFKSKGINTLQLIHLLEQVHIDTYRSTLP 424
>UniRef50_Q9HI38 Cluster: Serine hydroxymethyltransferase; n=5;
Thermoplasmatales|Rep: Serine hydroxymethyltransferase -
Thermoplasma acidophilum
Length = 426
Score = 37.1 bits (82), Expect = 0.39
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Frame = +3
Query: 57 LCEGLISRGYSIAT---GGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIG 227
L E L + G+++ G T+ H VD+ G G LE C + NKN +P D
Sbjct: 292 LAEELYANGFNVLAEKRGFTESHTMAVDVSKNG-GGKYVAETLEKCGIILNKNLLPWDDN 350
Query: 228 --ALNPSGIRL 254
+ NPSGIR+
Sbjct: 351 KKSQNPSGIRI 361
>UniRef50_A0D4A6 Cluster: Chromosome undetermined scaffold_37, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_37,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 804
Score = 36.7 bits (81), Expect = 0.52
Identities = 22/94 (23%), Positives = 49/94 (52%), Gaps = 4/94 (4%)
Frame = +2
Query: 194 LQQEHRARRHWRAQPQRH-QTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVS-GL 367
L E+R+ +H + RH QT + L T+ E ++DI++D D+ + +E +
Sbjct: 102 LSTENRSFKHKISAHNRHLQTESIKLITQQFTEQNVDIIIDNQDKQQEIDIECSNIDMQQ 161
Query: 368 KLVDFNKAI--EENAEFKKKIENLKEEVENYSKS 463
K + FN ++ +F+++++N + + + + S
Sbjct: 162 KKISFNYLFNDQKKKKFRQRVQNFQSKEQKKTSS 195
>UniRef50_Q2R3T6 Cluster: Expressed protein; n=6; Oryza sativa|Rep:
Expressed protein - Oryza sativa subsp. japonica (Rice)
Length = 276
Score = 35.1 bits (77), Expect = 1.6
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = +2
Query: 254 RTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENL 433
RTPALT R K + + ++ DR LK K V+ +K +E+N FKKK+ +
Sbjct: 49 RTPALTWRDYKRSTNERIMSPADRVLKEFWYCFKCDPTDKVEADKVLEQN--FKKKVPQM 106
>UniRef50_A2E8Z5 Cluster: Viral A-type inclusion protein, putative;
n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
protein, putative - Trichomonas vaginalis G3
Length = 4057
Score = 35.1 bits (77), Expect = 1.6
Identities = 19/62 (30%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
Frame = +2
Query: 287 EADIDIVVDFIDRALKXGLEI---IKVSGLKLVDFNKAIEENAEFKKKIENLKEEVENYS 457
E I ++ + I++ K ++ I + KL DF+ ++N+E+K KIE L+EE+ +Y
Sbjct: 1042 EEQITLLEEEIEKISKENSDLKAKILENEAKLDDFDDVSKQNSEYKAKIEQLEEELADYE 1101
Query: 458 KS 463
+
Sbjct: 1102 SN 1103
>UniRef50_Q2FQJ9 Cluster: Methyl-accepting chemotaxis sensory
transducer; n=1; Methanospirillum hungatei JF-1|Rep:
Methyl-accepting chemotaxis sensory transducer -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 1332
Score = 35.1 bits (77), Expect = 1.6
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 13/93 (13%)
Frame = +2
Query: 221 HWRAQPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIK------------VSG 364
H RA RHQ L +G+ E +D VV+ I+ A++ E + V G
Sbjct: 945 HTRADVNRHQGSYATLV-KGINET-LDAVVEPIEEAMRVAKEYARCNLATSFNPNLVVKG 1002
Query: 365 LKLVDFNKAIEE-NAEFKKKIENLKEEVENYSK 460
+ DF ++++ + K IENL EE+E+ SK
Sbjct: 1003 -EFADFKNSLDKIGTDISKTIENLNEEIESLSK 1034
>UniRef50_A2DDP2 Cluster: Viral A-type inclusion protein, putative;
n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
protein, putative - Trichomonas vaginalis G3
Length = 2120
Score = 34.3 bits (75), Expect = 2.8
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +2
Query: 383 NKAIEENAEFKKKIENLKEEVENYSKS 463
NK +EN K++IENLKEE+E +KS
Sbjct: 939 NKLQQENNSLKQEIENLKEEIEQNNKS 965
Score = 34.3 bits (75), Expect = 2.8
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +2
Query: 383 NKAIEENAEFKKKIENLKEEVENYSKS 463
NK +EN K++IENLKEE+E +KS
Sbjct: 1354 NKLQQENNSLKQEIENLKEEIEQNNKS 1380
Score = 34.3 bits (75), Expect = 2.8
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +2
Query: 383 NKAIEENAEFKKKIENLKEEVENYSKS 463
NK +EN K++IENLKEE+E +KS
Sbjct: 1749 NKLQQENNSLKQEIENLKEEIEQNNKS 1775
Score = 34.3 bits (75), Expect = 2.8
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +2
Query: 383 NKAIEENAEFKKKIENLKEEVENYSKS 463
NK +EN K++IENLKEE+E +KS
Sbjct: 1898 NKLQQENNSLKQEIENLKEEIEQNNKS 1924
Score = 34.3 bits (75), Expect = 2.8
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +2
Query: 383 NKAIEENAEFKKKIENLKEEVENYSKS 463
NK +EN K++IENLKEE+E +KS
Sbjct: 2047 NKLQQENNSLKQEIENLKEEIEQNNKS 2073
>UniRef50_A0RQ55 Cluster: Putative uncharacterized protein; n=1;
Campylobacter fetus subsp. fetus 82-40|Rep: Putative
uncharacterized protein - Campylobacter fetus subsp.
fetus (strain 82-40)
Length = 615
Score = 33.9 bits (74), Expect = 3.7
Identities = 21/72 (29%), Positives = 35/72 (48%)
Frame = +2
Query: 248 QTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIE 427
QT++ L + + E + V+D I + +K +I+ +L + E EF K I
Sbjct: 242 QTKSDKLNIKSV-EVQMPKVLDQITQIVKNSEQILSKINFELPNLKDIKEIKNEFIKTIN 300
Query: 428 NLKEEVENYSKS 463
N+K E+EN S
Sbjct: 301 NIKTEIENIKSS 312
>UniRef50_Q23DL9 Cluster: TBC domain containing protein; n=1;
Tetrahymena thermophila SB210|Rep: TBC domain containing
protein - Tetrahymena thermophila SB210
Length = 988
Score = 33.9 bits (74), Expect = 3.7
Identities = 17/58 (29%), Positives = 31/58 (53%)
Frame = +2
Query: 296 IDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKEEVENYSKSFP 469
I+ + +++ K +++ KV+ + KA E E+KK I + E EN+SK +P
Sbjct: 154 IEKTAELVEKGTKTQIDLQKVTHHSVQLKFKAEESQEEYKKTINQVNLEWENFSKQYP 211
>UniRef50_Q4RSG4 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF15000, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 571
Score = 33.5 bits (73), Expect = 4.8
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +3
Query: 21 RISETGDKE-RAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVAC 197
R+ + GD + RAA+ E L+ GY G V + +D G GLRG A + LE
Sbjct: 206 RLEQAGDPDLRAAVREALVLLGYHAPVKGRGVRILSID--GGGLRGLLALQTLETLEALT 263
Query: 198 NK 203
K
Sbjct: 264 GK 265
>UniRef50_Q6YQM5 Cluster: Chromosome segregation ATPase homolog;
n=13; Candidatus Phytoplasma asteris|Rep: Chromosome
segregation ATPase homolog - Onion yellows phytoplasma
Length = 215
Score = 33.1 bits (72), Expect = 6.4
Identities = 19/47 (40%), Positives = 31/47 (65%), Gaps = 3/47 (6%)
Frame = +2
Query: 317 IDRALKXGLEIIKVSG-LKLVD--FNKAIEENAEFKKKIENLKEEVE 448
ID+ ++ GL I + G +K ++ K IEENAE + +IE LKE+++
Sbjct: 91 IDKWVQQGLHIEALEGTIKALENASGKYIEENAELRHEIETLKEKIK 137
>UniRef50_Q54DX0 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 431
Score = 33.1 bits (72), Expect = 6.4
Identities = 14/38 (36%), Positives = 26/38 (68%)
Frame = +2
Query: 347 IIKVSGLKLVDFNKAIEENAEFKKKIENLKEEVENYSK 460
++K+ GLK+ F EN+E ++KI++ ++E+ NY K
Sbjct: 41 VMKLRGLKVAVFGLE-RENSELRQKIDSQEKEISNYQK 77
>UniRef50_A2DKA7 Cluster: C-myc binding protein, putative; n=1;
Trichomonas vaginalis G3|Rep: C-myc binding protein,
putative - Trichomonas vaginalis G3
Length = 129
Score = 33.1 bits (72), Expect = 6.4
Identities = 22/63 (34%), Positives = 37/63 (58%), Gaps = 3/63 (4%)
Frame = +2
Query: 266 LTTRGLKEADIDIVVDFIDRALKXG-LEIIK--VSGLKLVDFNKAIEENAEFKKKIENLK 436
L +GL + I+V F + + K +E I+ S + VD N+ ++ENAE ++KIE K
Sbjct: 56 LEEKGLMKHLTTILVHFYENSDKDHPIEYIQQYFSTMNGVDINQVLKENAEIQQKIEEAK 115
Query: 437 EEV 445
++V
Sbjct: 116 KKV 118
>UniRef50_Q28KQ5 Cluster: TRAP dicarboxylate transporter-DctP
subunit; n=1; Jannaschia sp. CCS1|Rep: TRAP
dicarboxylate transporter-DctP subunit - Jannaschia sp.
(strain CCS1)
Length = 326
Score = 32.7 bits (71), Expect = 8.4
Identities = 17/45 (37%), Positives = 27/45 (60%)
Frame = +2
Query: 311 DFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKEEV 445
DF DRA GLEI + +G++++D EE A + + + L EE+
Sbjct: 264 DFYDRAAARGLEIAREAGVEIIDLTP--EERARWDEAMAPLIEEL 306
>UniRef50_Q0S584 Cluster: Monooxygenase; n=2; Bacteria|Rep:
Monooxygenase - Rhodococcus sp. (strain RHA1)
Length = 515
Score = 32.7 bits (71), Expect = 8.4
Identities = 14/44 (31%), Positives = 25/44 (56%)
Frame = +2
Query: 278 GLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAE 409
GL E +D V+D + A + G+E+++V FN A+++ E
Sbjct: 409 GLAETQLDYVIDGLTTAERQGIEVLEVRDQPFRRFNDAVQKGLE 452
>UniRef50_Q45KZ0 Cluster: Structural maintenance of chromosome 2;
n=1; Toxoplasma gondii|Rep: Structural maintenance of
chromosome 2 - Toxoplasma gondii
Length = 1186
Score = 32.7 bits (71), Expect = 8.4
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +2
Query: 317 IDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKEEVE 448
+++ L+ E I+ L D KAIEE ++ K K+E++++E+E
Sbjct: 861 LEKDLQSVQEDIEKRTQGLADLQKAIEEKSKLKAKVEDVRKEIE 904
>UniRef50_A2FY63 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 1165
Score = 32.7 bits (71), Expect = 8.4
Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 3/36 (8%)
Frame = +2
Query: 374 VDFNKAIEENAEFKKKIENL-KEEVE--NYSKSFPL 472
++F K +EEN KK+I+NL KE +E NY+ PL
Sbjct: 345 LNFAKMMEENERLKKEIDNLMKERIEKDNYNDQIPL 380
>UniRef50_Q9NZR2 Cluster: Low-density lipoprotein receptor-related
protein 1B precursor; n=65; Euteleostomi|Rep: Low-density
lipoprotein receptor-related protein 1B precursor - Homo
sapiens (Human)
Length = 4599
Score = 32.7 bits (71), Expect = 8.4
Identities = 11/17 (64%), Positives = 15/17 (88%)
Frame = +1
Query: 100 AAPTCTSRSWICAASGC 150
A+PTC+SR +ICA+ GC
Sbjct: 3590 ASPTCSSREYICASDGC 3606
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 494,195,168
Number of Sequences: 1657284
Number of extensions: 8146840
Number of successful extensions: 29053
Number of sequences better than 10.0: 57
Number of HSP's better than 10.0 without gapping: 27720
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 29023
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 52479343733
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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