Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= wdV30215
(677 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 91 4e-18
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 91 4e-18
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 91 4e-18
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 91 4e-18
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 91 4e-18
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 91 4e-18
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 91 4e-18
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 91 4e-18
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 91 4e-18
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 90 8e-18
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 90 8e-18
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 90 8e-18
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 90 8e-18
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 90 8e-18
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 90 8e-18
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 90 8e-18
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 90 8e-18
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 90 8e-18
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 77 8e-14
Y14489-1|CAB54842.1| 92|Homo sapiens cytosolic serine hydroxym... 56 1e-07
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 33 1.2
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 33 1.2
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 33 1.2
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 33 1.2
L34688-1|AAB00324.1| 136|Homo sapiens C219-reactive peptide pro... 32 2.2
D87742-1|BAA13448.1| 1193|Homo sapiens KIAA0268 protein. 32 2.2
AL592148-11|CAI40473.1| 785|Homo sapiens C219-reactive peptide ... 32 2.2
AL592148-7|CAI40469.1| 1907|Homo sapiens C219-reactive peptide (... 32 2.2
CR542281-1|CAG47076.1| 312|Homo sapiens SCYE1 protein. 30 8.7
BC014051-1|AAH14051.1| 312|Homo sapiens small inducible cytokin... 30 8.7
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 164 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 223
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 224 RPSGLRL 230
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 224 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 282
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 283 KYQAAVQALREEVESFASLFPLPGLPDF 310
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 337 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 396
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 397 RPSGLRL 403
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 397 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 455
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 456 KYQAAVQALREEVESFASLFPLPGLPDF 483
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 298 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 357
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 358 RPSGLRL 364
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 358 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 416
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 417 KYQAAVQALREEVESFASLFPLPGLPDF 444
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 337 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 396
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 397 RPSGLRL 403
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 397 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 455
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 456 KYQAAVQALREEVESFASLFPLPGLPDF 483
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 337 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 396
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 397 RPSGLRL 403
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 397 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 455
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 456 KYQAAVQALREEVESFASLFPLPGLPDF 483
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 337 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 396
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 397 RPSGLRL 403
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 397 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 455
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 456 KYQAAVQALREEVESFASLFPLPGLPDF 483
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 298 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 357
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 358 RPSGLRL 364
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 358 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 416
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 417 KYQAAVQALREEVESFASLFPLPGLPDF 444
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 337 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 396
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 397 RPSGLRL 403
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 397 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 455
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 456 KYQAAVQALREEVESFASFFPLPGLPDF 483
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 90.6 bits (215), Expect = 4e-18
Identities = 43/67 (64%), Positives = 47/67 (70%)
Frame = +3
Query: 54 ALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGAL 233
AL E L GY I TGG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL
Sbjct: 337 ALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSAL 396
Query: 234 NPSGIRL 254
PSG+RL
Sbjct: 397 RPSGLRL 403
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 397 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 455
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 456 KYQAAVQALREEVESFASLFPLPGLPDF 483
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 335 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 394
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 395 RSAITPGGLRL 405
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 408 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 466
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 467 RVEQFARAFPMPGFDEH 483
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 326 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 385
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 386 RSAITPGGLRL 396
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 399 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 457
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 458 RVEQFARAFPMPGFDEH 474
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 356 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 415
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 416 RSAITPGGLRL 426
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 429 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 487
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 488 RVEQFARAFPMPGFDEH 504
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 332 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 391
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 392 RSAITPGGLRL 402
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 405 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 463
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 464 RVEQFARAFPMPGFDEH 480
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 356 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 415
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 416 RSAITPGGLRL 426
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 429 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 487
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 488 RVEQFARAFPMPGFDEH 504
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 346 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 405
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 406 RSAITPGGLRL 416
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 419 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 477
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 478 RVEQFARAFPMPGFDEH 494
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 356 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 415
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 416 RSAITPGGLRL 426
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 429 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 487
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 488 RVEQFARAFPMPGFDEH 504
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 356 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 415
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 416 RSAITPGGLRL 426
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R +E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 429 PALTSRQFREDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 487
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 488 RVEQFARAFPMPGFDEH 504
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/71 (59%), Positives = 50/71 (70%)
Frame = +3
Query: 42 KERAALCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGD 221
K A+ + L+ RGYS+ +GGTD HL LVDLR GL GA AERVLEL S+ NKNT PGD
Sbjct: 356 KNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGD 415
Query: 222 IGALNPSGIRL 254
A+ P G+RL
Sbjct: 416 RSAITPGGLRL 426
Score = 69.7 bits (163), Expect = 9e-12
Identities = 32/77 (41%), Positives = 51/77 (66%)
Frame = +2
Query: 260 PALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE 439
PALT+R E D VVDFID + GLE+ K KL DF + +++E +++ NL++
Sbjct: 429 PALTSRQFHEDDFRRVVDFIDEGVNIGLEV-KSKTAKLQDFKSFLLKDSETSQRLANLRQ 487
Query: 440 EVENYSKSFPLPGFDKY 490
VE ++++FP+PGFD++
Sbjct: 488 RVEQFARAFPMPGFDEH 504
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 76.6 bits (180), Expect = 8e-14
Identities = 35/52 (67%), Positives = 39/52 (75%)
Frame = +3
Query: 99 GGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDIGALNPSGIRL 254
GG+D HL LVDLR G G AE+VLE CS+ACNKNT PGD AL PSG+RL
Sbjct: 272 GGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRL 323
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 317 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 375
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 376 KYQAAVQALREEVESFASLFPLPGLPDF 403
>Y14489-1|CAB54842.1| 92|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 92
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Frame = +2
Query: 233 QPQRHQTRTPALTTRGLKEADIDIVVDFIDRALKXGLEIIKVSGLK--LVDFNKAIEENA 406
+P + TPALT+RGL E D V FI R ++ L+I +G++ L +F + + +
Sbjct: 6 RPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGD- 64
Query: 407 EFKKKIENLKEEVENYSKSFPLPGFDKY 490
+++ ++ L+EEVE+++ FPLPG +
Sbjct: 65 KYQAAVQALREEVESFASLFPLPGLPDF 92
>AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppressor
protein protein.
Length = 1537
Score = 32.7 bits (71), Expect = 1.2
Identities = 11/17 (64%), Positives = 15/17 (88%)
Frame = +1
Query: 100 AAPTCTSRSWICAASGC 150
A+PTC+SR +ICA+ GC
Sbjct: 914 ASPTCSSREYICASDGC 930
>AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein
receptor related protein-deleted in tumor protein.
Length = 4599
Score = 32.7 bits (71), Expect = 1.2
Identities = 11/17 (64%), Positives = 15/17 (88%)
Frame = +1
Query: 100 AAPTCTSRSWICAASGC 150
A+PTC+SR +ICA+ GC
Sbjct: 3590 ASPTCSSREYICASDGC 3606
>AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein.
Length = 1126
Score = 32.7 bits (71), Expect = 1.2
Identities = 11/17 (64%), Positives = 15/17 (88%)
Frame = +1
Query: 100 AAPTCTSRSWICAASGC 150
A+PTC+SR +ICA+ GC
Sbjct: 448 ASPTCSSREYICASDGC 464
>AB209707-1|BAD92944.1| 1720|Homo sapiens low density
lipoprotein-related protein 1B variant protein.
Length = 1720
Score = 32.7 bits (71), Expect = 1.2
Identities = 11/17 (64%), Positives = 15/17 (88%)
Frame = +1
Query: 100 AAPTCTSRSWICAASGC 150
A+PTC+SR +ICA+ GC
Sbjct: 711 ASPTCSSREYICASDGC 727
>L34688-1|AAB00324.1| 136|Homo sapiens C219-reactive peptide
protein.
Length = 136
Score = 31.9 bits (69), Expect = 2.2
Identities = 13/22 (59%), Positives = 18/22 (81%)
Frame = +2
Query: 395 EENAEFKKKIENLKEEVENYSK 460
EENA KKK E L++E+E++SK
Sbjct: 46 EENARLKKKKEQLQQEIEDWSK 67
>D87742-1|BAA13448.1| 1193|Homo sapiens KIAA0268 protein.
Length = 1193
Score = 31.9 bits (69), Expect = 2.2
Identities = 13/22 (59%), Positives = 18/22 (81%)
Frame = +2
Query: 395 EENAEFKKKIENLKEEVENYSK 460
EENA KKK E L++E+E++SK
Sbjct: 637 EENARLKKKKEQLQQEIEDWSK 658
>AL592148-11|CAI40473.1| 785|Homo sapiens C219-reactive peptide
(FLJ39207) protein.
Length = 785
Score = 31.9 bits (69), Expect = 2.2
Identities = 13/22 (59%), Positives = 18/22 (81%)
Frame = +2
Query: 395 EENAEFKKKIENLKEEVENYSK 460
EENA KKK E L++E+E++SK
Sbjct: 229 EENARLKKKKEQLQQEIEDWSK 250
>AL592148-7|CAI40469.1| 1907|Homo sapiens C219-reactive peptide
(FLJ39207) protein.
Length = 1907
Score = 31.9 bits (69), Expect = 2.2
Identities = 13/22 (59%), Positives = 18/22 (81%)
Frame = +2
Query: 395 EENAEFKKKIENLKEEVENYSK 460
EENA KKK E L++E+E++SK
Sbjct: 1351 EENARLKKKKEQLQQEIEDWSK 1372
>CR542281-1|CAG47076.1| 312|Homo sapiens SCYE1 protein.
Length = 312
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Frame = +2
Query: 284 KEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE-----EVE 448
K A+ D +++++ + + L+ + L + K ENA+ KK+IE LK+ E++
Sbjct: 14 KGAEADQIIEYLKQQVSL-LKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQ 72
Query: 449 NYSKSFPLP 475
N K P P
Sbjct: 73 NGVKQIPFP 81
>BC014051-1|AAH14051.1| 312|Homo sapiens small inducible cytokine
subfamily E, member 1 (endothelial monocyte-activating
protein.
Length = 312
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Frame = +2
Query: 284 KEADIDIVVDFIDRALKXGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKE-----EVE 448
K A+ D +++++ + + L+ + L + K ENA+ KK+IE LK+ E++
Sbjct: 14 KGAEADQIIEYLKQQVSL-LKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQ 72
Query: 449 NYSKSFPLP 475
N K P P
Sbjct: 73 NGVKQIPFP 81
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 70,883,528
Number of Sequences: 237096
Number of extensions: 1130190
Number of successful extensions: 3063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2910
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3043
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7671262118
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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