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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdV10954
         (617 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P55084 Cluster: Trifunctional enzyme subunit beta, mito...    61   2e-08
UniRef50_Q08VP3 Cluster: 3-ketoacyl-CoA thiolase; n=1; Stigmatel...    42   0.012
UniRef50_Q2IN02 Cluster: Acetyl-CoA C-acyltransferase; n=3; Myxo...    41   0.027
UniRef50_Q5YQT4 Cluster: Putative acyl-CoA thiolase; n=1; Nocard...    40   0.036
UniRef50_Q8ESF0 Cluster: Thiolase B; n=5; Bacteria|Rep: Thiolase...    37   0.33 
UniRef50_Q2J8N8 Cluster: Acetyl-CoA C-acyltransferase; n=64; Bac...    37   0.44 
UniRef50_Q8EN18 Cluster: Beta-ketothiolase; n=4; Bacteria|Rep: B...    36   0.77 
UniRef50_UPI00005A4329 Cluster: PREDICTED: hypothetical protein ...    36   1.0  
UniRef50_Q39N04 Cluster: Acetyl-CoA C-acetyltransferase; n=29; B...    36   1.0  
UniRef50_A1SXV9 Cluster: Acetyl-CoA acetyltransferases; n=1; Psy...    36   1.0  
UniRef50_A1IDF1 Cluster: Acetyl-CoA C-acyltransferase; n=1; Cand...    36   1.0  
UniRef50_Q0VJV2 Cluster: Like moricin; n=3; Manduca sexta|Rep: L...    36   1.0  
UniRef50_Q811H0 Cluster: EG382639 protein; n=12; Eutheria|Rep: E...    35   1.4  
UniRef50_Q1AVE6 Cluster: UV-endonuclease uvde; n=2; Bacteria|Rep...    35   1.4  
UniRef50_Q0SDR4 Cluster: Acetyl-CoA C-acetyltransferase; n=31; B...    35   1.8  
UniRef50_P14611 Cluster: Acetyl-CoA acetyltransferase; n=43; Bac...    35   1.8  
UniRef50_A0JU34 Cluster: Acetyl-CoA acetyltransferases; n=37; Ac...    34   2.4  
UniRef50_Q4RZ84 Cluster: Chromosome undetermined SCAF14954, whol...    33   5.5  
UniRef50_Q9KT59 Cluster: 3-ketoacyl-CoA thiolase; n=113; Proteob...    33   5.5  
UniRef50_Q81Y70 Cluster: Acetyl-CoA acetyltransferase; n=11; Bac...    33   7.2  
UniRef50_A1UKD6 Cluster: Putative uncharacterized protein; n=16;...    33   7.2  
UniRef50_Q9RRK9 Cluster: Acetyl-CoA acetyltransferase; n=12; Bac...    32   9.5  
UniRef50_Q0RV54 Cluster: Probable acetyl-CoA C-acyltransferase; ...    32   9.5  
UniRef50_Q4Q698 Cluster: Thiolase protein-like protein; n=7; Try...    32   9.5  
UniRef50_O29070 Cluster: 3-ketoacyl-CoA thiolase; n=2; cellular ...    32   9.5  

>UniRef50_P55084 Cluster: Trifunctional enzyme subunit beta,
           mitochondrial precursor (TP-beta) [Includes:
           3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA
           acyltransferase) (Beta-ketothiolase)]; n=49; cellular
           organisms|Rep: Trifunctional enzyme subunit beta,
           mitochondrial precursor (TP-beta) [Includes:
           3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA
           acyltransferase) (Beta-ketothiolase)] - Homo sapiens
           (Human)
          Length = 474

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 25/38 (65%), Positives = 31/38 (81%)
 Frame = +2

Query: 503 RSYLRDFTYVAQDPVDQLLLGPAYGIPKILDKVGLKVN 616
           ++YLRDF YV+QDP DQLLLGP Y  PK+L+K GL +N
Sbjct: 334 KAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMN 371



 Score = 34.7 bits (76), Expect = 1.8
 Identities = 15/25 (60%), Positives = 19/25 (76%)
 Frame = +1

Query: 433 YQTDGASACLVMSEAKAKELGLKPK 507
           + TDGASA L+M+E KA  +G KPK
Sbjct: 310 FLTDGASAMLIMAEEKALAMGYKPK 334


>UniRef50_Q08VP3 Cluster: 3-ketoacyl-CoA thiolase; n=1; Stigmatella
           aurantiaca DW4/3-1|Rep: 3-ketoacyl-CoA thiolase -
           Stigmatella aurantiaca DW4/3-1
          Length = 378

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 18/33 (54%), Positives = 21/33 (63%)
 Frame = +2

Query: 509 YLRDFTYVAQDPVDQLLLGPAYGIPKILDKVGL 607
           YLR   Y A DP DQLL GPAY +P  L + G+
Sbjct: 297 YLRAHAYAATDPGDQLLQGPAYAVPVALKRAGM 329



 Score = 32.3 bits (70), Expect = 9.5
 Identities = 14/22 (63%), Positives = 18/22 (81%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLKP 504
           TDGA+A L+MSE KA+ LG +P
Sbjct: 273 TDGAAALLLMSEEKARALGYEP 294


>UniRef50_Q2IN02 Cluster: Acetyl-CoA C-acyltransferase; n=3;
           Myxococcales|Rep: Acetyl-CoA C-acyltransferase -
           Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 435

 Score = 40.7 bits (91), Expect = 0.027
 Identities = 16/35 (45%), Positives = 24/35 (68%)
 Frame = +2

Query: 509 YLRDFTYVAQDPVDQLLLGPAYGIPKILDKVGLKV 613
           +++ + Y A DP DQLL GPAY  P  L++ GL++
Sbjct: 299 FVKAYAYAALDPRDQLLQGPAYAAPVALERAGLRL 333



 Score = 32.7 bits (71), Expect = 7.2
 Identities = 13/22 (59%), Positives = 19/22 (86%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLKP 504
           TDGA+A ++MSE +AK LG++P
Sbjct: 275 TDGAAALVLMSEERAKALGIRP 296


>UniRef50_Q5YQT4 Cluster: Putative acyl-CoA thiolase; n=1; Nocardia
           farcinica|Rep: Putative acyl-CoA thiolase - Nocardia
           farcinica
          Length = 430

 Score = 40.3 bits (90), Expect = 0.036
 Identities = 15/31 (48%), Positives = 23/31 (74%)
 Frame = +2

Query: 515 RDFTYVAQDPVDQLLLGPAYGIPKILDKVGL 607
           R ++YV+ DP DQ+L+GPA  +P+ LD  G+
Sbjct: 296 RSWSYVSVDPTDQVLIGPAISMPRALDAAGM 326



 Score = 32.7 bits (71), Expect = 7.2
 Identities = 14/22 (63%), Positives = 18/22 (81%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLKP 504
           TDGASA L+MSE +A+ LG +P
Sbjct: 270 TDGASAVLLMSEERARALGYRP 291


>UniRef50_Q8ESF0 Cluster: Thiolase B; n=5; Bacteria|Rep: Thiolase B
           - Oceanobacillus iheyensis
          Length = 394

 Score = 37.1 bits (82), Expect = 0.33
 Identities = 15/25 (60%), Positives = 20/25 (80%)
 Frame = +1

Query: 430 CYQTDGASACLVMSEAKAKELGLKP 504
           C + DGASA ++M E++AK LGLKP
Sbjct: 249 CGRNDGASALVIMKESRAKHLGLKP 273


>UniRef50_Q2J8N8 Cluster: Acetyl-CoA C-acyltransferase; n=64;
           Bacteria|Rep: Acetyl-CoA C-acyltransferase - Frankia sp.
           (strain CcI3)
          Length = 397

 Score = 36.7 bits (81), Expect = 0.44
 Identities = 15/23 (65%), Positives = 20/23 (86%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLKPK 507
           TDGASA L+MSE +A +LGL+P+
Sbjct: 255 TDGASAVLIMSETRANKLGLRPR 277


>UniRef50_Q8EN18 Cluster: Beta-ketothiolase; n=4; Bacteria|Rep:
           Beta-ketothiolase - Oceanobacillus iheyensis
          Length = 383

 Score = 35.9 bits (79), Expect = 0.77
 Identities = 15/23 (65%), Positives = 20/23 (86%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLKPK 507
           +DGA+A L+MS  KA+ELGLKP+
Sbjct: 240 SDGAAALLIMSREKAQELGLKPR 262


>UniRef50_UPI00005A4329 Cluster: PREDICTED: hypothetical protein
           XP_860641; n=1; Canis lupus familiaris|Rep: PREDICTED:
           hypothetical protein XP_860641 - Canis familiaris
          Length = 185

 Score = 35.5 bits (78), Expect = 1.0
 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
 Frame = -1

Query: 605 GRLCPRSWECRRRA--PTAAGPRDPERRM*S---PAGSFGLRPSSLAFASDITR 459
           GRL PR+W CR R+  P A GP  P+  +     P G+ G  PS L     +TR
Sbjct: 65  GRL-PRTWGCRARSLRPGATGPAHPDLELPGRLPPTGAAGPAPSDLGPPGQLTR 117


>UniRef50_Q39N04 Cluster: Acetyl-CoA C-acetyltransferase; n=29;
           Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 423

 Score = 35.5 bits (78), Expect = 1.0
 Identities = 16/23 (69%), Positives = 19/23 (82%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLKPK 507
           +DGA+A LVMSE KA  LGLKP+
Sbjct: 281 SDGAAALLVMSEQKAARLGLKPR 303


>UniRef50_A1SXV9 Cluster: Acetyl-CoA acetyltransferases; n=1;
           Psychromonas ingrahamii 37|Rep: Acetyl-CoA
           acetyltransferases - Psychromonas ingrahamii (strain 37)
          Length = 437

 Score = 35.5 bits (78), Expect = 1.0
 Identities = 16/25 (64%), Positives = 18/25 (72%)
 Frame = +1

Query: 430 CYQTDGASACLVMSEAKAKELGLKP 504
           C  TDGA A L+M E+KAKELG  P
Sbjct: 275 CPITDGAGAVLIMLESKAKELGYSP 299



 Score = 33.1 bits (72), Expect = 5.5
 Identities = 13/36 (36%), Positives = 23/36 (63%)
 Frame = +2

Query: 509 YLRDFTYVAQDPVDQLLLGPAYGIPKILDKVGLKVN 616
           YL+ ++Y    P +++ LGP Y   K+LDK G+ ++
Sbjct: 302 YLKAYSYAGLQP-ERMGLGPVYATSKLLDKTGMAIS 336


>UniRef50_A1IDF1 Cluster: Acetyl-CoA C-acyltransferase; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep: Acetyl-CoA
           C-acyltransferase - Candidatus Desulfococcus oleovorans
           Hxd3
          Length = 394

 Score = 35.5 bits (78), Expect = 1.0
 Identities = 15/22 (68%), Positives = 18/22 (81%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLKP 504
           TDGA+  ++MSE K KELGLKP
Sbjct: 249 TDGAAVSVIMSENKVKELGLKP 270



 Score = 35.5 bits (78), Expect = 1.0
 Identities = 14/22 (63%), Positives = 18/22 (81%)
 Frame = +2

Query: 548 DQLLLGPAYGIPKILDKVGLKV 613
           D++ +GP Y IPK+LDK GLKV
Sbjct: 285 DEMGVGPRYAIPKLLDKAGLKV 306


>UniRef50_Q0VJV2 Cluster: Like moricin; n=3; Manduca sexta|Rep: Like
           moricin - Manduca sexta (Tobacco hawkmoth) (Tobacco
           hornworm)
          Length = 248

 Score = 35.5 bits (78), Expect = 1.0
 Identities = 15/20 (75%), Positives = 15/20 (75%)
 Frame = +2

Query: 83  MGDSNHPVSGGPYARLPTRA 142
           MGD NH  SG PYA LPTRA
Sbjct: 1   MGDGNHSPSGRPYASLPTRA 20


>UniRef50_Q811H0 Cluster: EG382639 protein; n=12; Eutheria|Rep:
           EG382639 protein - Mus musculus (Mouse)
          Length = 355

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
 Frame = +3

Query: 444 RRLRLPRDVRGKGQGARPQTEAT-CGTSHTSLRIPWTSCCWGPPTAFPRSWTKSA 605
           R+L    + R  G+G  P+  AT CG++ TS R P ++ CW   T    +WT +A
Sbjct: 26  RKLAERAESRACGEGISPRAAATRCGSTATSSRYPPSAACWTSCTR--AAWTCTA 78


>UniRef50_Q1AVE6 Cluster: UV-endonuclease uvde; n=2; Bacteria|Rep:
           UV-endonuclease uvde - Rubrobacter xylanophilus (strain
           DSM 9941 / NBRC 16129)
          Length = 321

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/42 (54%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
 Frame = +1

Query: 442 DGASACLVMSEAKAKELGLKPKL-PAGLHIRRSGSRGPAAVG 564
           DG  A  VM EAK KEL L+P L P G   RR  +R PAA G
Sbjct: 263 DGREAD-VMVEAKGKELALEPLLPPGGAPERREDARKPAAGG 303


>UniRef50_Q0SDR4 Cluster: Acetyl-CoA C-acetyltransferase; n=31;
           Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
           Rhodococcus sp. (strain RHA1)
          Length = 411

 Score = 34.7 bits (76), Expect = 1.8
 Identities = 14/23 (60%), Positives = 19/23 (82%)
 Frame = +1

Query: 436 QTDGASACLVMSEAKAKELGLKP 504
           Q DGA+ACLV + A+A+ LGL+P
Sbjct: 265 QNDGAAACLVTTRAQAERLGLRP 287


>UniRef50_P14611 Cluster: Acetyl-CoA acetyltransferase; n=43;
           Bacteria|Rep: Acetyl-CoA acetyltransferase - Ralstonia
           eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
           337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
           428 / Stanier337))
          Length = 393

 Score = 34.7 bits (76), Expect = 1.8
 Identities = 16/21 (76%), Positives = 18/21 (85%)
 Frame = +1

Query: 442 DGASACLVMSEAKAKELGLKP 504
           DGA+A +VMS AKAKELGL P
Sbjct: 252 DGAAAVVVMSAAKAKELGLTP 272


>UniRef50_A0JU34 Cluster: Acetyl-CoA acetyltransferases; n=37;
           Actinomycetales|Rep: Acetyl-CoA acetyltransferases -
           Arthrobacter sp. (strain FB24)
          Length = 412

 Score = 34.3 bits (75), Expect = 2.4
 Identities = 14/25 (56%), Positives = 20/25 (80%)
 Frame = +1

Query: 430 CYQTDGASACLVMSEAKAKELGLKP 504
           C   DGA+A +VMS+ +A+ELGL+P
Sbjct: 266 CPLNDGAAALVVMSDGRARELGLEP 290


>UniRef50_Q4RZ84 Cluster: Chromosome undetermined SCAF14954, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14954,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 280

 Score = 33.1 bits (72), Expect = 5.5
 Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 11/67 (16%)
 Frame = +3

Query: 441 GRRLRLPRDVR----GKGQGARPQTEATCGTSHTSLRIP-------WTSCCWGPPTAFPR 587
           GRR R     R    G G G  P T  +  ++ TS R P       WT C W  P+A   
Sbjct: 73  GRRWRCSTCARPPTCGSGGGCSPSTTPSRASARTSPRCPTRSGCPRWTRCAW--PSATST 130

Query: 588 SWTKSAS 608
           SW  S S
Sbjct: 131 SWRSSCS 137


>UniRef50_Q9KT59 Cluster: 3-ketoacyl-CoA thiolase; n=113;
           Proteobacteria|Rep: 3-ketoacyl-CoA thiolase - Vibrio
           cholerae
          Length = 435

 Score = 33.1 bits (72), Expect = 5.5
 Identities = 12/36 (33%), Positives = 21/36 (58%)
 Frame = +2

Query: 509 YLRDFTYVAQDPVDQLLLGPAYGIPKILDKVGLKVN 616
           Y+R + + A      +L+GP+Y  P  LD+ G+ +N
Sbjct: 299 YIRSYAFAAIGVEKDMLMGPSYATPIALDRAGITLN 334



 Score = 32.7 bits (71), Expect = 7.2
 Identities = 14/21 (66%), Positives = 18/21 (85%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLK 501
           TDGA+A ++M E KAKELGL+
Sbjct: 275 TDGAAAIMLMREGKAKELGLE 295


>UniRef50_Q81Y70 Cluster: Acetyl-CoA acetyltransferase; n=11;
           Bacillus|Rep: Acetyl-CoA acetyltransferase - Bacillus
           anthracis
          Length = 363

 Score = 32.7 bits (71), Expect = 7.2
 Identities = 15/27 (55%), Positives = 18/27 (66%)
 Frame = +1

Query: 430 CYQTDGASACLVMSEAKAKELGLKPKL 510
           C   DGA A LVM E +A++LG KP L
Sbjct: 216 CGVNDGACAVLVMEEGQARKLGYKPVL 242


>UniRef50_A1UKD6 Cluster: Putative uncharacterized protein; n=16;
           Mycobacterium|Rep: Putative uncharacterized protein -
           Mycobacterium sp. (strain KMS)
          Length = 554

 Score = 32.7 bits (71), Expect = 7.2
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = +1

Query: 463 VMSEAKAKELGLKPKLPAGLHIRRSGSRGPAAVG 564
           V+  A+  ELGL+P++  G+H+R    R P   G
Sbjct: 209 VVRVAERPELGLRPRMAVGIHLRSGARRTPTFAG 242


>UniRef50_Q9RRK9 Cluster: Acetyl-CoA acetyltransferase; n=12;
           Bacteria|Rep: Acetyl-CoA acetyltransferase - Deinococcus
           radiodurans
          Length = 399

 Score = 32.3 bits (70), Expect = 9.5
 Identities = 14/22 (63%), Positives = 19/22 (86%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELGLKP 504
           +DGA+A L+MS  KA+ELG+KP
Sbjct: 248 SDGAAAVLLMSGEKAQELGVKP 269


>UniRef50_Q0RV54 Cluster: Probable acetyl-CoA C-acyltransferase;
           n=1; Rhodococcus sp. RHA1|Rep: Probable acetyl-CoA
           C-acyltransferase - Rhodococcus sp. (strain RHA1)
          Length = 383

 Score = 32.3 bits (70), Expect = 9.5
 Identities = 14/37 (37%), Positives = 23/37 (62%)
 Frame = +1

Query: 430 CYQTDGASACLVMSEAKAKELGLKPKLPAGLHIRRSG 540
           C   DGA+A +++SE  A+ LG++P +  G  +  SG
Sbjct: 197 CPTGDGAAAAVIVSERGAERLGIEPGIQIGASVIGSG 233


>UniRef50_Q4Q698 Cluster: Thiolase protein-like protein; n=7;
           Trypanosomatidae|Rep: Thiolase protein-like protein -
           Leishmania major
          Length = 440

 Score = 32.3 bits (70), Expect = 9.5
 Identities = 15/19 (78%), Positives = 16/19 (84%)
 Frame = +1

Query: 439 TDGASACLVMSEAKAKELG 495
           TDG SA LVMSE KAK+LG
Sbjct: 275 TDGGSAMLVMSEEKAKKLG 293


>UniRef50_O29070 Cluster: 3-ketoacyl-CoA thiolase; n=2; cellular
           organisms|Rep: 3-ketoacyl-CoA thiolase - Archaeoglobus
           fulgidus
          Length = 424

 Score = 32.3 bits (70), Expect = 9.5
 Identities = 14/23 (60%), Positives = 18/23 (78%)
 Frame = +1

Query: 442 DGASACLVMSEAKAKELGLKPKL 510
           DGA+A LVM E  AK+ GL+PK+
Sbjct: 283 DGAAAVLVMDEKAAKDYGLEPKV 305


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 621,112,582
Number of Sequences: 1657284
Number of extensions: 12225845
Number of successful extensions: 31796
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 30420
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31788
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 44807090004
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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