BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= wdV10860 (806 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 135 1e-30 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 98 3e-19 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 95 2e-18 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 93 6e-18 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 88 2e-16 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 87 4e-16 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 86 1e-15 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 85 2e-15 UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 84 3e-15 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 83 8e-15 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 83 8e-15 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 77 9e-15 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 77 9e-15 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 83 1e-14 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 83 1e-14 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 82 1e-14 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 81 2e-14 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 81 4e-14 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 80 6e-14 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 79 1e-13 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 79 1e-13 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 79 2e-13 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 79 2e-13 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 78 2e-13 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 78 2e-13 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 78 2e-13 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 78 2e-13 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 78 3e-13 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 77 7e-13 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 76 9e-13 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 76 1e-12 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 76 1e-12 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 76 1e-12 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 76 1e-12 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 76 1e-12 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 76 1e-12 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 76 1e-12 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 75 2e-12 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 75 2e-12 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 75 2e-12 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 74 4e-12 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 74 5e-12 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 74 5e-12 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 74 5e-12 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 73 6e-12 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 73 6e-12 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 73 6e-12 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 73 9e-12 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 73 9e-12 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 72 1e-11 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 72 2e-11 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 72 2e-11 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 72 2e-11 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 72 2e-11 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 71 3e-11 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 71 3e-11 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 71 3e-11 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 71 3e-11 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 71 3e-11 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 71 3e-11 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 71 3e-11 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 71 3e-11 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 70 6e-11 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 70 6e-11 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 70 6e-11 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 70 8e-11 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 70 8e-11 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 69 1e-10 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 69 1e-10 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 69 1e-10 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 69 1e-10 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 69 2e-10 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 69 2e-10 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 69 2e-10 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 69 2e-10 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 68 2e-10 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 68 2e-10 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 68 2e-10 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 68 2e-10 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 68 2e-10 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 68 2e-10 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 68 2e-10 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 68 2e-10 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 68 3e-10 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 68 3e-10 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 3e-10 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 67 4e-10 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 67 4e-10 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 67 4e-10 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 67 6e-10 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 67 6e-10 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 67 6e-10 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 66 7e-10 UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 66 7e-10 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 66 1e-09 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 66 1e-09 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 66 1e-09 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 65 2e-09 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 65 2e-09 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 65 2e-09 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 65 2e-09 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 65 2e-09 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 65 2e-09 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 65 2e-09 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 65 2e-09 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 65 2e-09 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 64 3e-09 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 64 3e-09 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 64 4e-09 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 64 4e-09 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 64 4e-09 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 64 5e-09 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 64 5e-09 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 64 5e-09 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 64 5e-09 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 64 5e-09 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 63 7e-09 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 63 7e-09 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 63 7e-09 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 63 7e-09 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 63 9e-09 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 63 9e-09 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 63 9e-09 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 62 1e-08 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 62 1e-08 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 62 1e-08 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 62 1e-08 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 62 1e-08 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 62 2e-08 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 62 2e-08 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 62 2e-08 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 62 2e-08 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 62 2e-08 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 62 2e-08 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 62 2e-08 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 62 2e-08 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 61 3e-08 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 3e-08 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 61 3e-08 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 61 3e-08 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 3e-08 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 61 4e-08 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 60 5e-08 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 60 6e-08 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 60 6e-08 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 60 6e-08 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 60 6e-08 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 60 9e-08 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 59 1e-07 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 59 1e-07 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 59 1e-07 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 59 1e-07 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 59 1e-07 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 59 1e-07 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 59 1e-07 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 59 1e-07 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 59 1e-07 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 59 1e-07 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 58 2e-07 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 58 2e-07 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 58 3e-07 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 3e-07 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 58 3e-07 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 3e-07 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 58 3e-07 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 58 3e-07 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 58 3e-07 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 58 3e-07 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 58 3e-07 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 57 5e-07 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 57 5e-07 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 57 6e-07 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 57 6e-07 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 57 6e-07 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 56 8e-07 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 56 8e-07 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 56 8e-07 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 56 1e-06 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 56 1e-06 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 56 1e-06 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 56 1e-06 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 56 1e-06 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 56 1e-06 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 56 1e-06 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 55 2e-06 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 55 2e-06 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 55 2e-06 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 55 2e-06 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 55 2e-06 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 54 3e-06 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 54 3e-06 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 54 3e-06 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 54 3e-06 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 54 3e-06 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 54 4e-06 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 54 4e-06 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 54 4e-06 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 54 4e-06 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 54 6e-06 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 54 6e-06 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 54 6e-06 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 54 6e-06 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 53 7e-06 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 53 7e-06 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 53 1e-05 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 53 1e-05 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 53 1e-05 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 52 1e-05 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 2e-05 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 52 2e-05 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 52 2e-05 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 52 2e-05 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 2e-05 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 51 3e-05 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 51 3e-05 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 51 3e-05 UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 51 4e-05 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 51 4e-05 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 51 4e-05 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 51 4e-05 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 50 5e-05 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 50 5e-05 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 50 7e-05 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 50 7e-05 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 50 7e-05 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 50 9e-05 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 50 9e-05 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 50 9e-05 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 50 9e-05 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 50 9e-05 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 50 9e-05 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 50 9e-05 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 49 1e-04 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 49 1e-04 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 49 1e-04 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 49 1e-04 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 49 2e-04 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 49 2e-04 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 49 2e-04 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 48 2e-04 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 48 2e-04 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 48 3e-04 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 48 3e-04 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 48 3e-04 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 48 3e-04 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 48 4e-04 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 48 4e-04 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 48 4e-04 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 48 4e-04 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 48 4e-04 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 47 5e-04 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 47 5e-04 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 47 5e-04 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 47 5e-04 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 47 5e-04 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 47 6e-04 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 47 6e-04 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 46 8e-04 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 46 8e-04 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 46 8e-04 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 46 0.001 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 46 0.001 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 46 0.001 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 46 0.001 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 46 0.001 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 46 0.001 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 45 0.002 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 45 0.002 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 45 0.002 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 45 0.002 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 45 0.002 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 45 0.003 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 45 0.003 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 45 0.003 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 44 0.003 UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 44 0.005 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 44 0.005 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 44 0.005 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 44 0.005 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 44 0.006 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 44 0.006 UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.006 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 44 0.006 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.006 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 44 0.006 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 44 0.006 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 44 0.006 UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 43 0.008 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 43 0.008 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 43 0.008 UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 43 0.008 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 43 0.008 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 43 0.010 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 43 0.010 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 43 0.010 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 43 0.010 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 43 0.010 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 43 0.010 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 43 0.010 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 43 0.010 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 43 0.010 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 42 0.014 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 42 0.014 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.014 UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 42 0.018 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 42 0.018 UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 42 0.018 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 42 0.018 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 42 0.024 UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 42 0.024 UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 42 0.024 UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.024 UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 41 0.032 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 41 0.032 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 41 0.032 UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 41 0.032 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 41 0.042 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 41 0.042 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 41 0.042 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 41 0.042 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 41 0.042 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 41 0.042 UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 40 0.056 UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 40 0.056 UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 40 0.056 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 40 0.056 UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 40 0.074 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 40 0.074 UniRef50_Q8F4Y9 Cluster: Aldo/keto reductase family protein; n=4... 31 0.078 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 40 0.097 UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 40 0.097 UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 40 0.097 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 39 0.13 UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 39 0.13 UniRef50_Q12D62 Cluster: Aldo/keto reductase; n=12; Proteobacter... 39 0.13 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 39 0.13 UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 39 0.13 UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 39 0.13 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 39 0.13 UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.17 UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 39 0.17 UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 39 0.17 UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 39 0.17 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 39 0.17 UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 38 0.23 UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 38 0.23 UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 38 0.23 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 38 0.23 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.23 UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 38 0.23 UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 38 0.23 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 38 0.30 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 38 0.30 UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 38 0.30 UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 38 0.30 UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 38 0.30 UniRef50_Q5K825 Cluster: Aryl-alcohol dehydrogenase, putative; n... 38 0.30 UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 38 0.39 UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 38 0.39 UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 38 0.39 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 38 0.39 UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 38 0.39 UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 38 0.39 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 38 0.39 UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 37 0.52 UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 37 0.52 UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 37 0.52 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 37 0.52 UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 37 0.69 UniRef50_Q1IYI7 Cluster: Aldo/keto reductase; n=3; Deinococcus g... 37 0.69 UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.69 UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 37 0.69 UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.69 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 37 0.69 UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 0.91 UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 36 0.91 UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 36 0.91 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 36 0.91 UniRef50_Q1IXS0 Cluster: Putative aldehyde reductase; n=1; Deino... 36 0.91 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 36 0.91 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 36 0.91 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 36 0.91 UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 36 0.91 UniRef50_Q98G15 Cluster: Mll3531 protein; n=3; Bacteria|Rep: Mll... 36 1.2 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 36 1.2 UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 36 1.2 UniRef50_Q2NSC7 Cluster: Putative oxidoreductase; n=1; Sodalis g... 36 1.2 UniRef50_Q28U06 Cluster: Aldo/keto reductase; n=1; Jannaschia sp... 36 1.2 UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 36 1.2 UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 36 1.2 UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 36 1.2 UniRef50_Q7SHH4 Cluster: Putative uncharacterized protein NCU029... 36 1.2 UniRef50_Q0CV71 Cluster: Putative uncharacterized protein; n=2; ... 36 1.2 UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 36 1.2 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 36 1.2 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 36 1.6 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 36 1.6 UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 36 1.6 UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 36 1.6 UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 36 1.6 UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 36 1.6 UniRef50_Q011A7 Cluster: Putative aldo/keto reductase family pro... 36 1.6 UniRef50_A6R162 Cluster: Predicted protein; n=1; Ajellomyces cap... 36 1.6 UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 36 1.6 UniRef50_Q5V0P8 Cluster: Oxidoreductase; n=2; Halobacteriaceae|R... 36 1.6 UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 35 2.1 UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 35 2.1 UniRef50_Q28MK3 Cluster: Aldo/keto reductase; n=19; Alphaproteob... 35 2.1 UniRef50_Q1LDA0 Cluster: Aldo/keto reductase; n=1; Ralstonia met... 35 2.1 UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 35 2.1 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 35 2.1 UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 35 2.1 UniRef50_Q9Y0Z1 Cluster: CG11970-PA; n=2; Eumetazoa|Rep: CG11970... 35 2.1 UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 35 2.1 UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 35 2.1 UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 35 2.8 UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 35 2.8 UniRef50_A6UAY5 Cluster: Acyltransferase 3; n=1; Sinorhizobium m... 35 2.8 UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 35 2.8 UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 35 2.8 UniRef50_A0UUU7 Cluster: Aldo/keto reductase; n=2; Clostridiacea... 35 2.8 UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 35 2.8 UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 35 2.8 UniRef50_UPI0000E87D03 Cluster: Aldo/keto reductase; n=1; Methyl... 34 3.7 UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 34 3.7 UniRef50_A0K0K8 Cluster: Aryl-alcohol dehydrogenase (NADP(+)); n... 34 3.7 UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 34 3.7 UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 34 3.7 UniRef50_A6RNJ6 Cluster: Putative uncharacterized protein; n=1; ... 34 3.7 UniRef50_Q93L10 Cluster: Putative uncharacterized protein; n=1; ... 34 4.8 UniRef50_Q1MJ49 Cluster: Putative general stress protein; n=2; R... 34 4.8 UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 34 4.8 UniRef50_Q9VUI5 Cluster: CG3396-PA; n=2; Sophophora|Rep: CG3396-... 34 4.8 UniRef50_Q1JST0 Cluster: Aldo-keto reductase, putative; n=1; Tox... 34 4.8 UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyce... 34 4.8 UniRef50_Q2USD3 Cluster: Voltage-gated shaker-like K+ channel; n... 34 4.8 UniRef50_Q8ZYV2 Cluster: Oxidoreductase, conjectural; n=3; Pyrob... 34 4.8 UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 34 4.8 UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 33 6.4 UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 33 6.4 UniRef50_A5NUR1 Cluster: Aldo/keto reductase precursor; n=2; Alp... 33 6.4 UniRef50_A5GVR8 Cluster: Possible oxidoreductase; n=14; Cyanobac... 33 6.4 UniRef50_A3BN45 Cluster: Putative uncharacterized protein; n=2; ... 33 6.4 UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 33 6.4 UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 33 6.4 UniRef50_UPI0000DB7378 Cluster: PREDICTED: similar to Fasciclin-... 33 8.5 UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 33 8.5 UniRef50_Q72CZ6 Cluster: Conserved domain protein; n=1; Desulfov... 33 8.5 UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel, shaker... 33 8.5 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 33 8.5 UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 33 8.5 UniRef50_Q1MEN6 Cluster: Putative oxidoreductase precursor; n=1;... 33 8.5 UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 33 8.5 UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 33 8.5 UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 33 8.5 UniRef50_A3WMV9 Cluster: Sensory box protein/GGDEF domain protei... 33 8.5 UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 33 8.5 UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 33 8.5 UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 33 8.5 UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 33 8.5 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 135 bits (327), Expect = 1e-30 Identities = 54/89 (60%), Positives = 74/89 (83%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EA++MKI+EGV+KRED+F+TTKLWNT H+R +VA A+ ++L K GLDY+DL+LMHWPI L Sbjct: 86 EAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHWPIAL 145 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 N DYSHS+ D++ETWR E+ ++G K+ Sbjct: 146 NEDYSHSNTDYLETWRATEEMVKLGYTKS 174 Score = 109 bits (263), Expect = 6e-23 Identities = 48/70 (68%), Positives = 61/70 (87%) Frame = +1 Query: 49 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228 ++T++VP LKM N R+MPAI LGTYLGFD+ G V SKDKQLR+VVM+AID+GYRHFDTA+ Sbjct: 17 SATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAA 76 Query: 229 VYETEQEIGK 258 +Y TE E+G+ Sbjct: 77 IYNTEAEVGE 86 Score = 95.9 bits (228), Expect = 1e-18 Identities = 43/75 (57%), Positives = 57/75 (76%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IGLSNFNK Q+ VL+E TIKP A+QIEVH Q +Q++++ + + EG++VMGYSPF Sbjct: 170 GYTKSIGLSNFNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPF 229 Query: 686 GSLVARHGSTVEGPR 730 GSLV R G + GP+ Sbjct: 230 GSLVKRFGMDLPGPK 244 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 97.9 bits (233), Expect = 3e-19 Identities = 40/83 (48%), Positives = 61/83 (73%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 I++G+VKRE++F+TTKLWN +H R +V A+ +SL KLGL Y+DLYL+H P N + Sbjct: 86 IQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSPEATNENGDP 145 Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521 D+D + TW G+E+A+++G K+ Sbjct: 146 VDIDVLNTWNGMEEAKKLGLAKS 168 Score = 58.8 bits (136), Expect = 1e-07 Identities = 30/78 (38%), Positives = 44/78 (56%), Gaps = 2/78 (2%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+ K IG+SNF+ L+R++ P QIEVH Q+++V G+ VM YSPF Sbjct: 164 GLAKSIGVSNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPF 223 Query: 686 GSLVAR--HGSTVEGPRS 733 G V+R H + V+ R+ Sbjct: 224 GFYVSRGSHNNPVKNDRT 241 Score = 49.6 bits (113), Expect = 9e-05 Identities = 26/66 (39%), Positives = 42/66 (63%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 + P ++N+G +P++ LGT+ GF G + ++R V+ AI GYRH DTA++Y Sbjct: 23 KAPLKQLNDGNAIPSLALGTF-GF---GDIP----KVRQAVLWAIQAGYRHIDTAALYGN 74 Query: 241 EQEIGK 258 E+E+GK Sbjct: 75 EEEVGK 80 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 94.7 bits (225), Expect = 2e-18 Identities = 42/95 (44%), Positives = 58/95 (61%), Gaps = 11/95 (11%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 A++ KI +G +KREDIF+TTKLW H+ EV A SL+ LG DYIDL+L+HWP Sbjct: 59 AIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFK 118 Query: 438 A-----------DYSHSDVDFMETWRGLEDAQRMG 509 + SD D++ETW+G+E+ +R G Sbjct: 119 SGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQG 153 Score = 93.9 bits (223), Expect = 4e-18 Identities = 44/92 (47%), Positives = 60/92 (65%), Gaps = 8/92 (8%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI--- 428 A++ KI++G VKRED+F+TTKL H+ +EV A SL LGLDYIDLYL+HWPI Sbjct: 319 AIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLNDLGLDYIDLYLIHWPIRRY 378 Query: 429 -----GLNADYSHSDVDFMETWRGLEDAQRMG 509 + SD D++ETW+G+E+ +R G Sbjct: 379 FRHNKNASGKLLLSDTDYLETWKGMEECKRQG 410 Score = 71.7 bits (168), Expect = 2e-11 Identities = 32/74 (43%), Positives = 46/74 (62%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ + IG+SNFN +Q+ R+L+ IKP Q+EV L+ QK ++EFC+ + V G Sbjct: 406 CKRQGLARSIGVSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTG 465 Query: 674 YSPFGSLVARHGST 715 YSP G R+G T Sbjct: 466 YSPLGRPGNRYGIT 479 Score = 70.5 bits (165), Expect = 5e-11 Identities = 31/72 (43%), Positives = 43/72 (59%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ + IGLSNFN +Q+ R+L IKP Q+EV + QK ++EFC+ + V G Sbjct: 149 CKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTG 208 Query: 674 YSPFGSLVARHG 709 +SP G RHG Sbjct: 209 FSPLGRPGNRHG 220 Score = 59.3 bits (137), Expect = 1e-07 Identities = 32/66 (48%), Positives = 41/66 (62%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M VP++ N+G MP IGLGT+L SK ++ + V AI+VGYRH DTA YE Sbjct: 1 MPVPTVTFNDGYKMPMIGLGTFL---------SKPGEVAEAVKYAIEVGYRHVDTAFFYE 51 Query: 238 TEQEIG 255 E+EIG Sbjct: 52 NEKEIG 57 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 93.5 bits (222), Expect = 6e-18 Identities = 43/96 (44%), Positives = 63/96 (65%), Gaps = 11/96 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A++ KI++GVVKRED+F+ TK+WN + ++ V A SLKKLGL YIDLYL+HWP Sbjct: 62 KAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSY 121 Query: 435 NADYSH-----------SDVDFMETWRGLEDAQRMG 509 Y + +VD++ETWRG+E+ ++G Sbjct: 122 PILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLG 157 Score = 74.9 bits (176), Expect = 2e-12 Identities = 33/66 (50%), Positives = 46/66 (69%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ + IG+SNFN QQL R+L+ +IKP QIE+H+ QK++ EFC S+ + V G Sbjct: 153 CIKLGLTRSIGVSNFNSQQLTRLLESASIKPVMNQIELHINLNQKKLREFCASKSIAVTG 212 Query: 674 YSPFGS 691 YSPFG+ Sbjct: 213 YSPFGA 218 Score = 50.8 bits (116), Expect = 4e-05 Identities = 26/66 (39%), Positives = 38/66 (57%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 +V + +++G +P +GLGT+ G + ++ + V AID GYRHFD AS Y Sbjct: 4 KVDEITLSDGNKVPVLGLGTWQGGND-------PDEVENAVKLAIDAGYRHFDCASFYGN 56 Query: 241 EQEIGK 258 E EIGK Sbjct: 57 EAEIGK 62 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 88.2 bits (209), Expect = 2e-16 Identities = 39/87 (44%), Positives = 60/87 (68%), Gaps = 2/87 (2%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + V I + V R++IF+TTKLWN QH+ E A+++SLKKLGL+Y+DLYL+HWP+ + Sbjct: 61 DQVGRAIADSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLSV 118 Query: 435 N--ADYSHSDVDFMETWRGLEDAQRMG 509 + + + D DF++TWR L+ + G Sbjct: 119 DPKTEKPYDDYDFVDTWRNLQKIYKEG 145 Score = 48.4 bits (110), Expect = 2e-04 Identities = 24/61 (39%), Positives = 39/61 (63%), Gaps = 2/61 (3%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 VK IG+SNFNK++L+++L EG + P QIE H Q ++ ++ +S+ + + YSP Sbjct: 148 VKAIGVSNFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSPL 207 Query: 686 G 688 G Sbjct: 208 G 208 Score = 47.2 bits (107), Expect = 5e-04 Identities = 22/60 (36%), Positives = 36/60 (60%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG +PAIGLGT+L +++ K+ + A+ GY+H DTA+ Y E ++G+ Sbjct: 14 LNNGLKIPAIGLGTWLADEEDAAYKA--------TLTALKNGYKHIDTAAAYGNEDQVGR 65 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 87.4 bits (207), Expect = 4e-16 Identities = 42/91 (46%), Positives = 56/91 (61%), Gaps = 13/91 (14%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----------- 434 +KRED+FITTK+WNT H + +VA+ N SL L LDYIDLY+MHWP+G Sbjct: 68 LKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMFPR 127 Query: 435 --NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D +SDV ++ETW +ED + G K+ Sbjct: 128 TETGDIVYSDVHYLETWSAMEDLVKTGKCKS 158 Score = 64.9 bits (151), Expect = 2e-09 Identities = 31/72 (43%), Positives = 43/72 (59%) Frame = +2 Query: 473 DLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQS 652 DL + G+C K +GLSNFN +QL+ VL+ T+ P +Q+E H Q E++ FC+ Sbjct: 149 DLVKTGKC------KSLGLSNFNSKQLDDVLQHSTVPPSVLQVESHPFLPQVELLNFCRE 202 Query: 653 EGVVVMGYSPFG 688 VVV YSP G Sbjct: 203 RSVVVSAYSPLG 214 Score = 46.0 bits (104), Expect = 0.001 Identities = 23/62 (37%), Positives = 35/62 (56%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S+ + +G MP +GLGT+ K K ++ + A+D GYRHFD A +Y E+E Sbjct: 4 SVTLPSGHAMPLVGLGTW---------KLKADEVAGAIGAAVDAGYRHFDCALIYGNEKE 54 Query: 250 IG 255 +G Sbjct: 55 VG 56 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 85.8 bits (203), Expect = 1e-15 Identities = 40/100 (40%), Positives = 62/100 (62%), Gaps = 12/100 (12%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 A++ KI+EG+V R+++FIT+KLWNT H+ V A SL+ LG+DY+DLYLMHWP+ Sbjct: 59 AIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYK 118 Query: 438 ADYS------------HSDVDFMETWRGLEDAQRMG*LKA 521 + + D+D+++TW+ +ED G + A Sbjct: 119 SGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNA 158 Score = 54.8 bits (126), Expect = 2e-06 Identities = 25/63 (39%), Positives = 37/63 (58%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G+V IG+SNFN++Q+ R+L +KP +QIE H QK ++ C + V YS Sbjct: 153 SGLVNAIGVSNFNEKQINRLLCLAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSS 212 Query: 683 FGS 691 GS Sbjct: 213 LGS 215 Score = 52.8 bits (121), Expect = 1e-05 Identities = 26/66 (39%), Positives = 38/66 (57%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M PS +++GR+MP +GLGT+ +S + + V AID+GYRHFD A +Y Sbjct: 1 MSTPSFLLSSGRNMPMVGLGTW---------RSPPEVVAQAVKDAIDIGYRHFDCAHIYG 51 Query: 238 TEQEIG 255 E +G Sbjct: 52 NELHVG 57 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 85.0 bits (201), Expect = 2e-15 Identities = 45/100 (45%), Positives = 65/100 (65%), Gaps = 11/100 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A++ KI+ GVVKRED+FITTKLW T R V A+ SLKKL LDY+DLY+MH+P+ + Sbjct: 63 QAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPM 122 Query: 435 NA---DYSHSD--------VDFMETWRGLEDAQRMG*LKA 521 + D+ ++ VDF +TW LE+ + G +K+ Sbjct: 123 KSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKS 162 Score = 63.7 bits (148), Expect = 5e-09 Identities = 30/72 (41%), Positives = 48/72 (66%), Gaps = 2/72 (2%) Frame = +2 Query: 482 RIGRCSANGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 655 R+ C G+VK IG+SNFN +QLER+L K G KP Q+E HL Q++++++C+S+ Sbjct: 150 RLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESK 209 Query: 656 GVVVMGYSPFGS 691 +V++ Y G+ Sbjct: 210 DIVLVAYGALGT 221 Score = 52.4 bits (120), Expect = 1e-05 Identities = 28/62 (45%), Positives = 38/62 (61%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 +K+N+G +PA+G GTY V KSK + A+DVGYRH DTA Y+ E+EI Sbjct: 8 VKLNDGHLIPALGFGTY---KPKEVPKSKSLE---AACLALDVGYRHVDTAYAYQVEEEI 61 Query: 253 GK 258 G+ Sbjct: 62 GQ 63 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 84.2 bits (199), Expect = 3e-15 Identities = 42/91 (46%), Positives = 57/91 (62%), Gaps = 12/91 (13%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431 E + KI EGVVKRED+F+T+KLWNT HR V A +L+ L LDY+DLYL+HWP+G Sbjct: 61 EGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGY 120 Query: 432 --------LNAD---YSHSDVDFMETWRGLE 491 + D + SD D+++TW +E Sbjct: 121 QEGTELFPMGPDGKTFLFSDADYVDTWPEME 151 Score = 62.1 bits (144), Expect = 2e-08 Identities = 28/62 (45%), Positives = 39/62 (62%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+V+ IG+SNFN +Q++RVL I P QIE H Q ++ FC +G++V YSP Sbjct: 157 GLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPL 216 Query: 686 GS 691 GS Sbjct: 217 GS 218 Score = 50.0 bits (114), Expect = 7e-05 Identities = 27/65 (41%), Positives = 34/65 (52%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 VP+ NG +P GLGT+ S Q+ V AIDVGYRH D A VY+ E Sbjct: 6 VPNAIFKNGNSIPMFGLGTW---------NSPPGQVAQAVKDAIDVGYRHIDCAHVYQNE 56 Query: 244 QEIGK 258 E+G+ Sbjct: 57 HEVGE 61 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 83.0 bits (196), Expect = 8e-15 Identities = 40/100 (40%), Positives = 60/100 (60%), Gaps = 11/100 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-- 428 E ++ I++GVVKRED+F+T+KLWNT H + +V A +L LGLDY+DLYL+HW + Sbjct: 56 EGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAF 115 Query: 429 --GLNADYSHSD-------VDFMETWRGLEDAQRMG*LKA 521 G N + D + ETW+ +E+ G +K+ Sbjct: 116 EHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKS 155 Score = 59.3 bits (137), Expect = 1e-07 Identities = 28/65 (43%), Positives = 38/65 (58%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+VK +G++NF L +L IKP QIE+H Q ++V FC S+ + V YSPF Sbjct: 151 GLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPF 210 Query: 686 GSLVA 700 GS A Sbjct: 211 GSTEA 215 Score = 36.3 bits (80), Expect = 0.91 Identities = 20/62 (32%), Positives = 31/62 (50%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 L + N + +P +G GT+ + D+V AI GYRH D A +Y E+E+ Sbjct: 4 LTLRNKQTLPLLGYGTW---------ELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEV 54 Query: 253 GK 258 G+ Sbjct: 55 GE 56 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 83.0 bits (196), Expect = 8e-15 Identities = 36/75 (48%), Positives = 48/75 (64%), Gaps = 3/75 (4%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EA K E G VKREDIF+T+KLWN H++ +V A+ +LK L LDY+DLYLMHWP+ Sbjct: 56 EAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAF 115 Query: 435 NAD---YSHSDVDFM 470 + D D++ Sbjct: 116 KPSVNGFPEKDEDYL 130 Score = 60.5 bits (140), Expect = 5e-08 Identities = 26/76 (34%), Positives = 45/76 (59%) Frame = +2 Query: 464 LHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 643 LH L + G++K +G+SNF+K++LE + + P+ Q+E+H Q ++ + Sbjct: 137 LHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVELHPYLPQNDLYSY 196 Query: 644 CQSEGVVVMGYSPFGS 691 C EG+++ GYSP GS Sbjct: 197 CSKEGILLTGYSPLGS 212 Score = 42.3 bits (95), Expect = 0.014 Identities = 21/63 (33%), Positives = 36/63 (57%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 +LK +G +P+IGLGT+ KS + ++ V A++ GY+H D A+ Y+ E Sbjct: 3 TLKFRDGDSIPSIGLGTW---------KSDPEDVKKAVKIALENGYKHIDCAAAYDNEDA 53 Query: 250 IGK 258 +G+ Sbjct: 54 VGE 56 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 76.6 bits (180), Expect(2) = 9e-15 Identities = 32/57 (56%), Positives = 44/57 (77%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 ++ KI+EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G Sbjct: 50 IRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106 Score = 61.7 bits (143), Expect = 2e-08 Identities = 33/63 (52%), Positives = 39/63 (61%), Gaps = 2/63 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVL-KEGT-IKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 G+VK IG+SNFN +QLER+L K G KP QIE H QK ++ FCQS V V Y Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYR 221 Query: 680 PFG 688 P G Sbjct: 222 PLG 224 Score = 42.3 bits (95), Expect = 0.014 Identities = 21/54 (38%), Positives = 31/54 (57%) Frame = +1 Query: 94 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVG 47 Score = 26.6 bits (56), Expect(2) = 9e-15 Identities = 10/22 (45%), Positives = 14/22 (63%) Frame = +3 Query: 453 SDVDFMETWRGLEDAQRMG*LK 518 SD DF++TW +ED G +K Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 76.6 bits (180), Expect(2) = 9e-15 Identities = 32/57 (56%), Positives = 44/57 (77%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 ++ KI+EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G Sbjct: 50 IRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106 Score = 42.3 bits (95), Expect = 0.014 Identities = 21/54 (38%), Positives = 31/54 (57%) Frame = +1 Query: 94 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVG 47 Score = 37.9 bits (84), Expect = 0.30 Identities = 22/46 (47%), Positives = 31/46 (67%), Gaps = 2/46 (4%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMV 637 G+VK IG+SNFN +QLER+L K G KP QI + Q +Q+ ++ Sbjct: 162 GLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQ-IQRNVI 206 Score = 26.6 bits (56), Expect(2) = 9e-15 Identities = 10/22 (45%), Positives = 14/22 (63%) Frame = +3 Query: 453 SDVDFMETWRGLEDAQRMG*LK 518 SD DF++TW +ED G +K Sbjct: 144 SDTDFLDTWEAMEDLVITGLVK 165 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 82.6 bits (195), Expect = 1e-14 Identities = 41/96 (42%), Positives = 58/96 (60%), Gaps = 11/96 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW---- 422 EA+K ++EG VKRE++FIT+K+WNT H + + I+ L L L Y+DL L+HW Sbjct: 57 EALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGY 116 Query: 423 -------PIGLNADYSHSDVDFMETWRGLEDAQRMG 509 P G N +SDVD++ETW+ E AQ+ G Sbjct: 117 AEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAG 152 Score = 64.5 bits (150), Expect = 3e-09 Identities = 27/62 (43%), Positives = 41/62 (66%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G + IGLSNF Q++RV +KP +Q+E+H Q ++ EFC+ +G+VV+GYSP Sbjct: 152 GKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPL 211 Query: 686 GS 691 G+ Sbjct: 212 GN 213 Score = 52.0 bits (119), Expect = 2e-05 Identities = 26/65 (40%), Positives = 40/65 (61%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 V SLK+N+G +PAIGLGT+ +SK ++ + A+ GYRH D A VY+ + Sbjct: 2 VQSLKLNSGYSIPAIGLGTW---------QSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQ 52 Query: 244 QEIGK 258 +E+G+ Sbjct: 53 KEVGE 57 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 82.6 bits (195), Expect = 1e-14 Identities = 41/100 (41%), Positives = 60/100 (60%), Gaps = 11/100 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A+ KIE+G VKREDIF T+KLW+T HR V ++ +SL+KL LDY+DLYL+H+P+ L Sbjct: 63 QAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSL 122 Query: 435 -----------NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + + VD +TW +E + G K+ Sbjct: 123 KPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKS 162 Score = 54.8 bits (126), Expect = 2e-06 Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 2/69 (2%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVV 664 +C G+ K IG+SNFN++QLE +L K G KP Q+E HL Q +++ +C+ +V Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIV 212 Query: 665 VMGYSPFGS 691 ++ Y G+ Sbjct: 213 LVAYGALGT 221 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/66 (31%), Positives = 39/66 (59%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++ +++N+G +P +G GTY + +K K + + AIDVG+ H D + +Y+ Sbjct: 4 KIQKIELNDGHSIPVLGFGTYATEEH---LKKKSMESTKI---AIDVGFCHIDCSHLYQN 57 Query: 241 EQEIGK 258 E+EIG+ Sbjct: 58 EEEIGQ 63 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 82.2 bits (194), Expect = 1e-14 Identities = 42/99 (42%), Positives = 57/99 (57%), Gaps = 15/99 (15%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434 A++ KIEEGVV RE++F+TTKLWNT H V A SL+ LGLDY+DL+L+H P G Sbjct: 62 AIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYE 121 Query: 435 --------------NADYSHSDVDFMETWRGLEDAQRMG 509 N + SD D+++TW+ +E G Sbjct: 122 FNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESG 160 Score = 61.7 bits (143), Expect = 2e-08 Identities = 28/62 (45%), Positives = 39/62 (62%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G V IG+SNFN +QLER+L +KP Q+E + QK ++EFC +VV +SP Sbjct: 159 SGRVHSIGVSNFNSEQLERILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSP 218 Query: 683 FG 688 FG Sbjct: 219 FG 220 Score = 55.6 bits (128), Expect = 1e-06 Identities = 29/65 (44%), Positives = 39/65 (60%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +P++K+NNG +MPAIGLGT + SK + VM AID G+RH DTA Y E Sbjct: 6 IPTVKLNNGLEMPAIGLGTSM---------SKGDECCKAVMTAIDEGFRHIDTAYNYRNE 56 Query: 244 QEIGK 258 +G+ Sbjct: 57 DVVGR 61 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 81.4 bits (192), Expect = 2e-14 Identities = 35/66 (53%), Positives = 46/66 (69%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IGLSNFN+ Q+ +LKE IKP +Q+EVH + QK ++EFCQ G++V GY+P Sbjct: 180 GRTKSIGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPL 239 Query: 686 GSLVAR 703 GS AR Sbjct: 240 GSPGAR 245 Score = 49.2 bits (112), Expect = 1e-04 Identities = 23/49 (46%), Positives = 33/49 (67%) Frame = +3 Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 KREDIF+T+KL + V + I SL+KLGL Y+D+YL+H P ++ Sbjct: 94 KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVH 142 Score = 37.1 bits (82), Expect = 0.52 Identities = 20/61 (32%), Positives = 36/61 (59%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 ++++G + P +GLGT+ G +++ L V+ A++ G H DT+ VY+ E+ IG Sbjct: 32 RLSSGHNFPIVGLGTH-GLNED--------VLETVLTGALEKGIGHIDTSFVYKNEETIG 82 Query: 256 K 258 K Sbjct: 83 K 83 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 80.6 bits (190), Expect = 4e-14 Identities = 32/52 (61%), Positives = 44/52 (84%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 I+E VKRED+FIT+KLWN HR +V A++D+LK+LGL+Y+DLYL+HWP+ Sbjct: 59 IKEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPV 110 Score = 44.4 bits (100), Expect = 0.003 Identities = 19/62 (30%), Positives = 37/62 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G VK IG+SNF+ + ++ +++ + P QIE H +Q E++ +++ + + YSP Sbjct: 153 GKVKAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPL 212 Query: 686 GS 691 G+ Sbjct: 213 GN 214 Score = 34.3 bits (75), Expect = 3.7 Identities = 19/64 (29%), Positives = 31/64 (48%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 V + +N G + +G GT+ ++ ++ V AI+ GYRH D A VY + Sbjct: 2 VGTTTLNTGASLELVGYGTW---------QAAPGEVGQGVKVAIETGYRHLDLAKVYSNQ 52 Query: 244 QEIG 255 E+G Sbjct: 53 PEVG 56 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 80.2 bits (189), Expect = 6e-14 Identities = 39/98 (39%), Positives = 61/98 (62%), Gaps = 10/98 (10%) Frame = +3 Query: 258 AVKMKIEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 AV IE+G++K R+++FIT+K WNT + A+ +LKKLG++Y+DLYL+HWP+ L Sbjct: 65 AVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRL 124 Query: 435 NAD------YSHSDV---DFMETWRGLEDAQRMG*LKA 521 D +S D+ D TW+ +E+ R+G K+ Sbjct: 125 RHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKS 162 Score = 54.4 bits (125), Expect = 3e-06 Identities = 28/65 (43%), Positives = 40/65 (61%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++P + +N+G MP IG+GT + + V L + + AI VGYRHFD+ASVY T Sbjct: 5 KIPEVLLNSGHKMPVIGMGTSVESRPSNDV------LASIFVDAIQVGYRHFDSASVYGT 58 Query: 241 EQEIG 255 E+ IG Sbjct: 59 EEAIG 63 Score = 51.2 bits (117), Expect = 3e-05 Identities = 25/83 (30%), Positives = 44/83 (53%) Frame = +2 Query: 464 LHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 643 + G + C G+ K IG+ N+ ++L ++L+ TI P Q+E++ Q + EF Sbjct: 144 IEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNLREF 203 Query: 644 CQSEGVVVMGYSPFGSLVARHGS 712 C+ +G+ V +SP G+ GS Sbjct: 204 CKQKGIHVSAWSPLGAYKIFWGS 226 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 79.4 bits (187), Expect = 1e-13 Identities = 35/99 (35%), Positives = 61/99 (61%), Gaps = 11/99 (11%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434 A++ KI++G+++R+D+FI +KLW T H ++ N SL L LDY+D YL+H+P+GL Sbjct: 32 AIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFNKSLSDLQLDYLDQYLVHFPVGLK 91 Query: 435 ----------NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + +D+D+++ WRG+E + G +K+ Sbjct: 92 KVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKVKS 130 Score = 63.7 bits (148), Expect = 5e-09 Identities = 26/64 (40%), Positives = 43/64 (67%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G VK IG+SNF +Q++R+L I P Q+E+H VQ +++++C+S+ + + +S Sbjct: 124 ATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHS 183 Query: 680 PFGS 691 PFGS Sbjct: 184 PFGS 187 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 79.0 bits (186), Expect = 1e-13 Identities = 40/94 (42%), Positives = 58/94 (61%), Gaps = 15/94 (15%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A++ KI EGV++RED+F+TTKLWNT H V +A S L + YIDL+LMH P+G+ Sbjct: 60 QAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGV 119 Query: 435 N-ADYSH--------------SDVDFMETWRGLE 491 + Y + SDVD++ETW+ +E Sbjct: 120 QFSGYEYADMQPKDAAGNMLFSDVDYVETWKAME 153 Score = 66.5 bits (155), Expect = 7e-10 Identities = 28/64 (43%), Positives = 43/64 (67%) Frame = +2 Query: 497 SANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 676 +A G V+ IGLSNFN +Q+ER+L+ T+KP Q+E + Q++++ FCQ+ G+ V Y Sbjct: 157 TAGGRVRSIGLSNFNSEQIERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAY 216 Query: 677 SPFG 688 P G Sbjct: 217 GPMG 220 Score = 59.3 bits (137), Expect = 1e-07 Identities = 30/66 (45%), Positives = 44/66 (66%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 +VP+++ +NG ++P +G GTYL Q G Q ++V +AID+GYRH DTA +YE Sbjct: 4 QVPTVRFSNGYEIPVLGYGTYLA--QKG-------QCVELVKKAIDLGYRHIDTAFLYEN 54 Query: 241 EQEIGK 258 E EIG+ Sbjct: 55 EVEIGQ 60 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 78.6 bits (185), Expect = 2e-13 Identities = 37/83 (44%), Positives = 52/83 (62%), Gaps = 2/83 (2%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW--PI 428 E+V I + V RED+F+TTKLWN H +A++ SL KLGLDY+DLYL+HW P Sbjct: 60 ESVGKAIADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPA 119 Query: 429 GLNADYSHSDVDFMETWRGLEDA 497 + ++ + D TWR +E+A Sbjct: 120 AMRDNWEQLNAD---TWRAMEEA 139 Score = 45.2 bits (102), Expect = 0.002 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = +1 Query: 49 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLR-DVVMRAIDVGYRHFDTA 225 A T + +NNG +P +G GT+ ++ D Q+ D V+ A+ GYRH DTA Sbjct: 3 ALTKLTDTYTLNNGTKIPIVGFGTW---------QTPDGQVAYDSVLAALKAGYRHIDTA 53 Query: 226 SVYETEQEIGK 258 + Y E+ +GK Sbjct: 54 AAYGNEESVGK 64 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 78.6 bits (185), Expect = 2e-13 Identities = 35/92 (38%), Positives = 58/92 (63%), Gaps = 13/92 (14%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 A++ K++EGVV R+++FIT+KLWNT H+ V A S++ LG+ Y++LYLMHWP+ Sbjct: 59 ALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYK 118 Query: 438 ADYSH-------------SDVDFMETWRGLED 494 + + D+D+++TWR +E+ Sbjct: 119 SGSDNLYPTCPDTNKAAFEDIDYVDTWRAMEN 150 Score = 56.8 bits (131), Expect = 6e-07 Identities = 25/62 (40%), Positives = 36/62 (58%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+ + IG+SNFN+QQ+ R+L +KP +QIE H QK ++ C + V YS Sbjct: 155 GLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCL 214 Query: 686 GS 691 GS Sbjct: 215 GS 216 Score = 53.2 bits (122), Expect = 7e-06 Identities = 25/66 (37%), Positives = 39/66 (59%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M P+ ++NG++MP +GLGT+ +S + + V AID+GYRHFD A +Y Sbjct: 1 MSTPNFLLSNGKNMPMLGLGTW---------RSPPEVVTQAVKDAIDIGYRHFDCAHIYG 51 Query: 238 TEQEIG 255 E ++G Sbjct: 52 NEAQVG 57 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 78.2 bits (184), Expect = 2e-13 Identities = 34/60 (56%), Positives = 43/60 (71%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440 +K K + VVKREDIFIT+KLWN +H +V QA + +LK L L Y+DLYLMHWP+ A Sbjct: 43 LKEKFDANVVKREDIFITSKLWNNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAYQA 102 Score = 62.9 bits (146), Expect = 9e-09 Identities = 25/63 (39%), Positives = 44/63 (69%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G K IGLSNF+ + ++RV+++ TI+P +Q+E+H Q++++EFC+ + V YSP Sbjct: 109 SGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSP 168 Query: 683 FGS 691 G+ Sbjct: 169 LGA 171 Score = 38.7 bits (86), Expect = 0.17 Identities = 18/34 (52%), Positives = 20/34 (58%) Frame = +1 Query: 154 SKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 SK Q+ V AID GYRH D A VY E E+G Sbjct: 7 SKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVG 40 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 78.2 bits (184), Expect = 2e-13 Identities = 37/97 (38%), Positives = 61/97 (62%), Gaps = 12/97 (12%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431 EA++ +I+ G + RE+IF+TTKLWNT H +V + L+ LG YIDLYLMH+P+G Sbjct: 75 EALRTQIKMGNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGY 134 Query: 432 ----------LNADYSHS-DVDFMETWRGLEDAQRMG 509 ++ D + ++D+++TWR +E+ ++G Sbjct: 135 KYVCDEILMPMSGDELQTVEIDYLDTWRAMENLVKLG 171 Score = 50.4 bits (115), Expect = 5e-05 Identities = 20/51 (39%), Positives = 37/51 (72%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEG 658 G+V+ IGLSNFN +Q++R+++ + KP Q+E+ +QK++V++C+ G Sbjct: 171 GMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNG 221 Score = 38.7 bits (86), Expect = 0.17 Identities = 18/36 (50%), Positives = 23/36 (63%) Frame = +1 Query: 151 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 K + Q V AI+ G+RHFDTA YE E+EIG+ Sbjct: 40 KLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGE 75 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 78.2 bits (184), Expect = 2e-13 Identities = 39/93 (41%), Positives = 56/93 (60%), Gaps = 8/93 (8%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431 +A+ KI EGVV RE++F+TTKL H V +A SL LGL+Y+DLYLMH P+G Sbjct: 60 QAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQ 119 Query: 432 -------LNADYSHSDVDFMETWRGLEDAQRMG 509 ++ +DVD+++TWR +E +G Sbjct: 120 KFHNDSNVHGTLELTDVDYLDTWREMEKLVDLG 152 Score = 62.5 bits (145), Expect = 1e-08 Identities = 28/64 (43%), Positives = 42/64 (65%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 P++++NNGR+MP +GLGT+ F+ + ++ A+DVGYRH DTA VYE E Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTR---------HALDVGYRHLDTAFVYENEA 56 Query: 247 EIGK 258 E+G+ Sbjct: 57 EVGQ 60 Score = 50.8 bits (116), Expect = 4e-05 Identities = 24/59 (40%), Positives = 34/59 (57%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+ + IGLSNFN Q ERVL I+P Q+E H Q+++ E + G+V+ Y P Sbjct: 152 GLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCP 210 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 78.2 bits (184), Expect = 2e-13 Identities = 36/64 (56%), Positives = 46/64 (71%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + V I++ V RE+IF+TTKLW TQH EVA ++ SLK+LGLDY+DLYLMHWP L Sbjct: 60 DQVGQAIKDSGVPREEIFVTTKLWCTQHHEPEVA--LDQSLKRLGLDYVDLYLMHWPARL 117 Query: 435 NADY 446 + Y Sbjct: 118 DPAY 121 Score = 54.4 bits (125), Expect = 3e-06 Identities = 27/64 (42%), Positives = 41/64 (64%), Gaps = 2/64 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVL-KEGT-IKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 G K +G+SNF+ L+ +L +G + P A Q+E+H Q E++ FC+S+G+VV YS Sbjct: 161 GKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYS 220 Query: 680 PFGS 691 P GS Sbjct: 221 PLGS 224 Score = 47.6 bits (108), Expect = 4e-04 Identities = 23/62 (37%), Positives = 35/62 (56%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 L +N G +P IGLGT+ +SK+ V+ A+ GYRH DTA++Y E ++ Sbjct: 12 LSLNTGAQIPQIGLGTW---------QSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62 Query: 253 GK 258 G+ Sbjct: 63 GQ 64 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 77.8 bits (183), Expect = 3e-13 Identities = 35/89 (39%), Positives = 53/89 (59%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EAV I++ +KRED+F+T+KLWNT + +A ++L +L +DY+DLYL+HWP Sbjct: 59 EAVGKGIKDSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANE 118 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + ETWR +ED G ++A Sbjct: 119 KQFGDDAAKINAETWRAMEDLYNEGKIRA 147 Score = 44.4 bits (100), Expect = 0.003 Identities = 22/63 (34%), Positives = 33/63 (52%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 + +NNG +P +G GT+ ++ V AI+ GYRH DTA+VY E+ Sbjct: 10 TFNLNNGVKIPCVGYGTF---------RTPADVAEQAVKEAIETGYRHIDTAAVYGNEEA 60 Query: 250 IGK 258 +GK Sbjct: 61 VGK 63 Score = 44.0 bits (99), Expect = 0.005 Identities = 20/66 (30%), Positives = 36/66 (54%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G ++ IG+SNF + ++K + P QIEVH E+V++ Q+ ++V ++P Sbjct: 143 GKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWPHTEVVKYLQAHNILVEAWAPL 202 Query: 686 GSLVAR 703 G A+ Sbjct: 203 GGQGAK 208 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 76.6 bits (180), Expect = 7e-13 Identities = 35/92 (38%), Positives = 58/92 (63%), Gaps = 3/92 (3%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + +K I +G VKRE++F+TTKLW+T + +V A +SLKKL L+Y+DLY++H P+ Sbjct: 57 DGIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTA 116 Query: 435 N---ADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + +++ + ETWR +E G +K+ Sbjct: 117 DKKTGEFTEEIIPIEETWREMEKLVEEGLVKS 148 Score = 54.4 bits (125), Expect = 3e-06 Identities = 23/62 (37%), Positives = 38/62 (61%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+VK IG+SNFN ++LE +L I+P Q E H+ + ++ +FC+ + + GY P Sbjct: 144 GLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIYYQRPKLHQFCKKHNIHITGYCPL 203 Query: 686 GS 691 G+ Sbjct: 204 GN 205 Score = 39.9 bits (89), Expect = 0.074 Identities = 24/59 (40%), Positives = 31/59 (52%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 +NNG +P +GLGT++ NG V V AI GYRH D A Y E+E+G Sbjct: 7 LNNGYKIPKLGLGTWMS--ANGEVGK-------AVEIAIKNGYRHIDCAKAYGNEKEVG 56 >UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyces cerevisiae YDR368w YPR1; n=1; Kluyveromyces lactis|Rep: Similarities with sp|Q12458 Saccharomyces cerevisiae YDR368w YPR1 - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 127 Score = 76.2 bits (179), Expect = 9e-13 Identities = 33/59 (55%), Positives = 46/59 (77%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 AV I + + RE+IF+TTKLWNTQ R + A A+N+SL++LGLDY+DL+L+HWP+ L Sbjct: 7 AVGKGIRDSGIPREEIFVTTKLWNTQQR--DPASALNESLERLGLDYVDLFLIHWPVPL 63 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 75.8 bits (178), Expect = 1e-12 Identities = 37/89 (41%), Positives = 53/89 (59%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EA+ + E V+RE++++TTKLW + QA DS +LG+DY+DLYLMHWP + Sbjct: 64 EALGKAVTESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPDSM 123 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 S +V +ETWR LE+ G +A Sbjct: 124 VPGRSSQEVR-LETWRALEELYDEGLCRA 151 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/59 (35%), Positives = 30/59 (50%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+ + IG+SNF L + G I P Q+E H ++VE C+ E +V GY P Sbjct: 147 GLCRAIGVSNFLIPHLNELKDSGGIVPHVNQVEFHPFQQPMKLVEHCRKENIVFEGYCP 205 Score = 35.5 bits (78), Expect = 1.6 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Frame = +1 Query: 52 STMEVPSLKMNNGRDMPAIGLGT--YLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 225 + + P++ ++NG ++P +GLGT Y G+ V+ + + G RH DTA Sbjct: 9 TALSCPAVPLHNGLNIPILGLGTSHYGGYSHEAVLYALQ-----------ECGIRHIDTA 57 Query: 226 SVYETEQEIGK 258 Y E+ +GK Sbjct: 58 KRYGCEEALGK 68 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 75.8 bits (178), Expect = 1e-12 Identities = 34/89 (38%), Positives = 58/89 (65%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 ++V I++ + R ++FITTKLWN+ H + +AI+ SL L LDY+D+YL+HWP Sbjct: 59 DSVGRAIQKSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPS 118 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + ++++ E+WR +E+A R G ++A Sbjct: 119 SMRDHWAEIN-AESWRAMEEAVRAGKIRA 146 Score = 42.3 bits (95), Expect = 0.014 Identities = 24/60 (40%), Positives = 33/60 (55%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG +P IG GT+ D G V + V+ A++ GYRH DTAS Y E +G+ Sbjct: 12 LNNGVKIPIIGFGTWQTPD--GEVAEES------VLAALNCGYRHIDTASAYGNEDSVGR 63 Score = 41.1 bits (92), Expect = 0.032 Identities = 20/62 (32%), Positives = 36/62 (58%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G ++ IG+SNF K L+ +++ IKP QI ++ ++Q E+V + ++ YSP Sbjct: 142 GKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFLNPSDLQSEVVTENKKLDLLSEAYSPL 201 Query: 686 GS 691 G+ Sbjct: 202 GT 203 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 75.8 bits (178), Expect = 1e-12 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 7/84 (8%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP----- 425 +K E+ VVKRED+FIT+KLW T H +V +A+N +LK L L+Y+DLYL+HWP Sbjct: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121 Query: 426 --IGLNADYSHSDVDFMETWRGLE 491 +G+ + + VD TW+ +E Sbjct: 122 GSVGIKPE-NLLPVDIPSTWKAME 144 Score = 44.8 bits (101), Expect = 0.003 Identities = 24/60 (40%), Positives = 33/60 (55%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 K+N G P++GLGT+ G+V D V A+ +GYRH D A +Y E+EIG Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVG-------DAVAAAVKIGYRHIDCAQIYGNEKEIG 59 Score = 41.5 bits (93), Expect = 0.024 Identities = 19/53 (35%), Positives = 33/53 (62%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGV 661 +G + IG+SNF+ ++L +L+ + P Q+E H Q ++ EFC+S+GV Sbjct: 149 SGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGV 201 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 75.8 bits (178), Expect = 1e-12 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 7/84 (8%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP----- 425 +K E+ VVKRED+FIT+KLW T H +V +A+N +LK L L+Y+DLYL+HWP Sbjct: 62 LKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK 121 Query: 426 --IGLNADYSHSDVDFMETWRGLE 491 +G+ + + VD TW+ +E Sbjct: 122 GSVGIKPE-NLLPVDIPSTWKAME 144 Score = 51.6 bits (118), Expect = 2e-05 Identities = 24/63 (38%), Positives = 39/63 (61%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G + IG+SNF+ ++L +L+ + P Q+E H Q ++ EFC+S+GV + YSP Sbjct: 149 SGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSP 208 Query: 683 FGS 691 GS Sbjct: 209 LGS 211 Score = 44.8 bits (101), Expect = 0.003 Identities = 24/60 (40%), Positives = 33/60 (55%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 K+N G P++GLGT+ G+V D V A+ +GYRH D A +Y E+EIG Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVG-------DAVAAAVKIGYRHIDCAQIYGNEKEIG 59 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 75.8 bits (178), Expect = 1e-12 Identities = 31/61 (50%), Positives = 44/61 (72%) Frame = +3 Query: 279 EGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSD 458 E VKRED+FIT+KLWNT H++ V A+ +L LGL Y+DLYL+HWP+ +Y+ +D Sbjct: 66 EATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAF--EYTSND 123 Query: 459 V 461 + Sbjct: 124 I 124 Score = 59.3 bits (137), Expect = 1e-07 Identities = 29/62 (46%), Positives = 37/62 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+VK IGLSNFN Q L VL IKP A Q+E+H Q E+ +FC + + YSP Sbjct: 150 GLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPL 209 Query: 686 GS 691 G+ Sbjct: 210 GN 211 Score = 46.0 bits (104), Expect = 0.001 Identities = 23/64 (35%), Positives = 37/64 (57%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 PS K+++G +P +G GT+ K++ + V A+D GYRH D A+VY E+ Sbjct: 3 PSFKLSSGHKIPLVGFGTW---------KAETTLVGKAVEVALDAGYRHIDCAAVYLNEK 53 Query: 247 EIGK 258 E+G+ Sbjct: 54 EVGE 57 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 75.8 bits (178), Expect = 1e-12 Identities = 35/79 (44%), Positives = 48/79 (60%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 E+V + V RED+FITTKLWNT+ A +S +KLG+DYIDLYL+HWP G Sbjct: 58 ESVGAGLRASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGK 117 Query: 435 NADYSHSDVDFMETWRGLE 491 + S ++++WR E Sbjct: 118 DI-LSKEGKKYLDSWRAFE 135 Score = 48.0 bits (109), Expect = 3e-04 Identities = 23/59 (38%), Positives = 35/59 (59%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 V+ IG+SNF+ LE VL T+ P Q+E+H N Q ++ FC ++ + V +SP G Sbjct: 143 VRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLG 201 Score = 36.3 bits (80), Expect = 0.91 Identities = 19/59 (32%), Positives = 30/59 (50%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 ++NG MP GLG + + + V A+ GYRH DTA++Y+ E+ +G Sbjct: 11 LSNGVKMPQFGLGVWQS--------PAGEVTENAVNWALCAGYRHIDTAAIYKNEESVG 61 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 75.8 bits (178), Expect = 1e-12 Identities = 41/98 (41%), Positives = 57/98 (58%), Gaps = 11/98 (11%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434 A++ K++E VVKR+D+FI +KLW T H ++ V A +L L LDY+DLYL+HWP G Sbjct: 58 ALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFK 117 Query: 435 -NADY---------SHSDVDFMETWRGLEDAQRMG*LK 518 DY SD DF++TW +E G +K Sbjct: 118 PGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVK 155 Score = 66.1 bits (154), Expect = 1e-09 Identities = 31/64 (48%), Positives = 44/64 (68%), Gaps = 2/64 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 G+VK IG+SNFN Q+ER+L + +K P QIE H Q++++E+C S+G+VV YS Sbjct: 152 GLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYS 211 Query: 680 PFGS 691 P GS Sbjct: 212 PLGS 215 Score = 55.6 bits (128), Expect = 1e-06 Identities = 28/61 (45%), Positives = 38/61 (62%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 L++NNG MP +GLGT+ KS Q+ + V AID+GYRH D A VY+ E+E+ Sbjct: 5 LELNNGTKMPTLGLGTW---------KSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEV 55 Query: 253 G 255 G Sbjct: 56 G 56 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 75.4 bits (177), Expect = 2e-12 Identities = 36/100 (36%), Positives = 58/100 (58%), Gaps = 11/100 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A+ + + R+++FIT+KLWN +HR +V QAI+ SLK L +DY+DLYLMHWP Sbjct: 55 KAIGRALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAF 114 Query: 435 -----------NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + D+D+++T++ +E + G KA Sbjct: 115 APGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKA 154 Score = 53.6 bits (123), Expect = 6e-06 Identities = 25/63 (39%), Positives = 42/63 (66%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G K IG+SNF+K ++ER+L+ +I P +Q+E+H Q + VE+ +S+G+ V YS Sbjct: 149 SGKTKAIGISNFSKGEMERLLESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYSS 208 Query: 683 FGS 691 G+ Sbjct: 209 LGN 211 Score = 52.4 bits (120), Expect = 1e-05 Identities = 27/63 (42%), Positives = 38/63 (60%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 + ++N G D+PAIG GT+ D+N D V+ A+ GYRH DTA+VY TE+ Sbjct: 7 TFRLNTGEDIPAIGFGTWQ--DENAQ--------EDAVLTALSAGYRHIDTAAVYGTEKA 56 Query: 250 IGK 258 IG+ Sbjct: 57 IGR 59 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 75.4 bits (177), Expect = 2e-12 Identities = 33/63 (52%), Positives = 47/63 (74%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A+K EEG+VKRED+FITTK+W + R E ++++ SL LGLDY+DL+L HWP+ L Sbjct: 63 QALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVL 120 Query: 435 NAD 443 + D Sbjct: 121 HGD 123 Score = 46.4 bits (105), Expect = 8e-04 Identities = 24/60 (40%), Positives = 36/60 (60%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 ++NG+ +PA+GLGT V +L++ V+ A+ GYRH DTA Y TE+ IG+ Sbjct: 12 LSNGKTIPALGLGT--------VPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/61 (39%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKE-GTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 VK IG+SN++ +L ++L KP QIE H Q+++V++C GV + YSP G Sbjct: 167 VKSIGVSNYSIPKLRKLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVG 226 Query: 689 S 691 S Sbjct: 227 S 227 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 74.9 bits (176), Expect = 2e-12 Identities = 36/82 (43%), Positives = 58/82 (70%), Gaps = 5/82 (6%) Frame = +3 Query: 258 AVKMKIEEGV----VKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHW 422 AV IEEG+ +KREDI++T+KLWN H E V + +N +L+ LGL+Y+DLYL+HW Sbjct: 82 AVGRGIEEGLKRAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHW 141 Query: 423 PIGLNADYSHSDVDFMETWRGL 488 PIG +++ ++D ++T++ + Sbjct: 142 PIGFSSN-GAKNLDHVQTYKSM 162 Score = 39.9 bits (89), Expect = 0.074 Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 691 V IG+SNF+ QL+ V+ GTI P Q+E+H Q V ++ G+ + YSP G+ Sbjct: 170 VLNIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIKMTAYSPLGN 228 Query: 692 L-VARHGST 715 H ST Sbjct: 229 TNPTYHSST 237 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 74.1 bits (174), Expect = 4e-12 Identities = 38/100 (38%), Positives = 57/100 (57%), Gaps = 11/100 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EA++ KI+E VKRED+FI +KLW+T ++ V +A ++L L LDY+DLYL+HWP G Sbjct: 57 EAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGF 116 Query: 435 NA-----------DYSHSDVDFMETWRGLEDAQRMG*LKA 521 + S F++ W +E+ G +KA Sbjct: 117 QSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKA 156 Score = 59.7 bits (138), Expect = 9e-08 Identities = 26/64 (40%), Positives = 42/64 (65%), Gaps = 2/64 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 G+VK +G+SNFN Q+ER+L + +K P Q+E H Q+++ ++C S+G+ + YS Sbjct: 152 GLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYS 211 Query: 680 PFGS 691 P GS Sbjct: 212 PLGS 215 Score = 48.0 bits (109), Expect = 3e-04 Identities = 25/57 (43%), Positives = 33/57 (57%) Frame = +1 Query: 88 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 G MP +GLGT+ KS ++R+ V AID GYRH D A VY+ E E+G+ Sbjct: 10 GAKMPIVGLGTW---------KSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGE 57 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 73.7 bits (173), Expect = 5e-12 Identities = 36/83 (43%), Positives = 50/83 (60%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 +++ + REDIF+TTK+WN A SL+KLG+DY+DLYL+HWP+ Sbjct: 58 LKDSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM------PD 111 Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521 D+ +M+TWR LE R G KA Sbjct: 112 EDL-YMDTWRALEQLYRDGKAKA 133 Score = 56.8 bits (131), Expect = 6e-07 Identities = 28/60 (46%), Positives = 38/60 (63%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G K IG+SNF+ L RVL+EGT+ P QIE+H Q+ + FCQ G+VV +SP Sbjct: 128 DGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSP 187 Score = 41.5 bits (93), Expect = 0.024 Identities = 21/60 (35%), Positives = 33/60 (55%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG MP +G G + K ++++ + V A+ VGYR DTA +YE E +G+ Sbjct: 6 LNNGLVMPQLGYGVF---------KVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGR 56 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 73.7 bits (173), Expect = 5e-12 Identities = 33/60 (55%), Positives = 41/60 (68%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 E + I EG+ RE+++ITTKLWNT HR V A S+ LGLDYIDLYL+H+PI L Sbjct: 61 EGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIAL 120 Score = 44.0 bits (99), Expect = 0.005 Identities = 24/70 (34%), Positives = 39/70 (55%) Frame = +1 Query: 49 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228 + ++VP +K+++ + MPA+GLG + K V AI VGYRH D+A+ Sbjct: 2 SDAIQVPGVKVSS-KSMPAVGLGLW---------KITQDSAAQAVYEAIKVGYRHLDSAA 51 Query: 229 VYETEQEIGK 258 Y EQ++G+ Sbjct: 52 DYGNEQQVGE 61 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/64 (32%), Positives = 36/64 (56%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G+V+ IG+ N++ L ++ IKP +QIE H Q+ ++ +S + V +SP Sbjct: 164 SGLVRQIGVCNYSAVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSP 223 Query: 683 FGSL 694 GSL Sbjct: 224 LGSL 227 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 73.7 bits (173), Expect = 5e-12 Identities = 40/90 (44%), Positives = 53/90 (58%), Gaps = 1/90 (1%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A+ EG++KREDIFITTK + + V +A+ +SLK+L LDY+DLYL H P Sbjct: 60 DALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPAST 119 Query: 435 NADYS-HSDVDFMETWRGLEDAQRMG*LKA 521 D S SDV + WRG E +G KA Sbjct: 120 KDDGSFRSDVKVEDIWRGFEKVYGLGLTKA 149 Score = 51.2 bits (117), Expect = 3e-05 Identities = 22/62 (35%), Positives = 36/62 (58%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+ K IG+SNFN+ Q+ R++ + A Q+E+HL QK E C+ +++ Y+ Sbjct: 145 GLTKAIGVSNFNESQIVRIMNIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYATL 204 Query: 686 GS 691 GS Sbjct: 205 GS 206 Score = 48.0 bits (109), Expect = 3e-04 Identities = 25/65 (38%), Positives = 38/65 (58%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 +VP ++NG MP+IGLGT+ + G + V+ A+ GYRH DTA++Y+ Sbjct: 4 KVPIFTLSNGVLMPSIGLGTWQMTGEEG---------KTVIRNAVLAGYRHIDTATLYQN 54 Query: 241 EQEIG 255 E +IG Sbjct: 55 EHQIG 59 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 73.3 bits (172), Expect = 6e-12 Identities = 36/95 (37%), Positives = 53/95 (55%), Gaps = 11/95 (11%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434 A++ KI +G VKRED+F T KLW+T H V A+ SLK L LDY+DL+++H P+ Sbjct: 65 AIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFK 124 Query: 435 ----------NADYSHSDVDFMETWRGLEDAQRMG 509 N + + + D +TW+ LE + G Sbjct: 125 PGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAG 159 Score = 62.1 bits (144), Expect = 2e-08 Identities = 29/69 (42%), Positives = 46/69 (66%), Gaps = 2/69 (2%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVV 664 +C G+V+ IG+SNFN +QLE +L +K P Q+E H+ Q +++EFC+S+ +V Sbjct: 154 KCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLLEFCKSKDIV 213 Query: 665 VMGYSPFGS 691 ++GYS GS Sbjct: 214 LVGYSVLGS 222 Score = 46.0 bits (104), Expect = 0.001 Identities = 24/62 (38%), Positives = 33/62 (53%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 +++N+G MP IG GTY K + AIDVGYRH D A +Y E+E+ Sbjct: 9 VELNDGHKMPVIGFGTY------APPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEV 62 Query: 253 GK 258 G+ Sbjct: 63 GR 64 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 73.3 bits (172), Expect = 6e-12 Identities = 36/78 (46%), Positives = 50/78 (64%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 + RED+F+T+K+WN E QA NDSL++LGLDY+DLYL+HWP G N+ + Sbjct: 72 LNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP-GNNS--------Y 122 Query: 468 METWRGLEDAQRMG*LKA 521 E+W+ LE G +KA Sbjct: 123 KESWQALETLYAEGKVKA 140 Score = 50.0 bits (114), Expect = 7e-05 Identities = 24/61 (39%), Positives = 35/61 (57%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G VK IG+SNF LE +L + P Q+E+H + QKE+ +FC+ + V +S Sbjct: 134 AEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDFCEKHDIKVQAWS 193 Query: 680 P 682 P Sbjct: 194 P 194 Score = 33.9 bits (74), Expect = 4.8 Identities = 20/62 (32%), Positives = 30/62 (48%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++ +NNG +P +GLG + + D++ VV I GYR DTA +Y E Sbjct: 8 TVTLNNGTKIPGMGLGVF---------QIPDEETAKVVEEGIINGYRLIDTAQIYGNESG 58 Query: 250 IG 255 G Sbjct: 59 TG 60 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 73.3 bits (172), Expect = 6e-12 Identities = 39/91 (42%), Positives = 58/91 (63%), Gaps = 2/91 (2%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLW--NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 EAV I+ V RE+IF+TTKLW N +++T +A +++SL+KL L+YIDLYL+HWP Sbjct: 52 EAVGKAIKARGVLREEIFVTTKLWRENLGYKQTRIA--LDESLRKLDLNYIDLYLIHWPA 109 Query: 429 GLNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 +Y +TWR +E+ Q G +K+ Sbjct: 110 NA-INYKDWQKTNADTWRAMEELQAEGKIKS 139 Score = 50.8 bits (116), Expect = 4e-05 Identities = 22/61 (36%), Positives = 35/61 (57%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G +K +G+SNF + LE + + + P QIE H Q ++ EFC++ G+ V +S Sbjct: 133 AEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQPQVTEFCKNHGIAVESWS 192 Query: 680 P 682 P Sbjct: 193 P 193 Score = 43.2 bits (97), Expect = 0.008 Identities = 21/60 (35%), Positives = 35/60 (58%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +N+G +P +G GTY ++ G+ KS K A+ +GYR DT ++Y+ E+ +GK Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGI-KSIQKS-------ALTLGYRLIDTVAIYQNEEAVGK 56 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 72.9 bits (171), Expect = 9e-12 Identities = 36/98 (36%), Positives = 59/98 (60%), Gaps = 9/98 (9%) Frame = +3 Query: 255 EAVKMKIEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 +A+ + EG++K R+++FIT+KLW + R V A+ +LK L L+YID+YL+HWP+ Sbjct: 64 DAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVS 123 Query: 432 L---NADYSHSDVDFME-----TWRGLEDAQRMG*LKA 521 N +Y DF++ W +E+ Q++G KA Sbjct: 124 SKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKA 161 Score = 58.4 bits (135), Expect = 2e-07 Identities = 26/73 (35%), Positives = 45/73 (61%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ K IG+SNF+ ++L VL + P Q+EV+ QK++ EFC+S G++V+ Sbjct: 153 CQKLGLTKAIGVSNFSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVA 212 Query: 674 YSPFGSLVARHGS 712 Y+ G++ +G+ Sbjct: 213 YAALGAVGTFYGT 225 Score = 46.0 bits (104), Expect = 0.001 Identities = 24/65 (36%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = +1 Query: 64 VPSLKMNNG-RDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 +P + +++G R MP +GLGT + + +R V A+ +GYRHFDTA++Y + Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVD------PETVRKAVTEALKLGYRHFDTAALYNS 58 Query: 241 EQEIG 255 EQ +G Sbjct: 59 EQPLG 63 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 72.9 bits (171), Expect = 9e-12 Identities = 38/99 (38%), Positives = 56/99 (56%), Gaps = 11/99 (11%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434 A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G Sbjct: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117 Query: 435 ----------NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + + SD + ++TW +E+ G +KA Sbjct: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156 Score = 65.3 bits (152), Expect = 2e-09 Identities = 30/64 (46%), Positives = 44/64 (68%), Gaps = 2/64 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 G+VK IG+SNFN Q+E +L + +K P QIE H Q++++++CQS+G+VV YS Sbjct: 152 GLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYS 211 Query: 680 PFGS 691 P GS Sbjct: 212 PLGS 215 Score = 54.4 bits (125), Expect = 3e-06 Identities = 29/61 (47%), Positives = 36/61 (59%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+ Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 253 G 255 G Sbjct: 56 G 56 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 72.1 bits (169), Expect = 1e-11 Identities = 32/82 (39%), Positives = 48/82 (58%), Gaps = 3/82 (3%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EA++ E G KRED+F+T+KLWN + R +V +A+ +L LG+ Y+DLYL+HWP+ Sbjct: 60 EALREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAW 119 Query: 435 NAD---YSHSDVDFMETWRGLE 491 ++ E W LE Sbjct: 120 KRGTVLQPDAEASIAECWSELE 141 Score = 51.2 bits (117), Expect = 3e-05 Identities = 27/70 (38%), Positives = 42/70 (60%), Gaps = 2/70 (2%) Frame = +2 Query: 479 ARIGRCSANGIVKGIGLSNFNKQQLERVLKE--GTIKPDAIQIEVHLQNVQKEMVEFCQS 652 + + RC A+G+V+ IG+SNFN+ QL + + I+P QIE H +V++ QS Sbjct: 138 SELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESHPLWSNDSLVKYSQS 197 Query: 653 EGVVVMGYSP 682 +G+ V YSP Sbjct: 198 KGLTVTAYSP 207 Score = 42.7 bits (96), Expect = 0.010 Identities = 21/58 (36%), Positives = 32/58 (55%) Frame = +1 Query: 85 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 NG +P +GLGT+ K++ ++RD V A+ GY H D A+ Y E E+G+ Sbjct: 12 NGLRIPRVGLGTW---------KARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGE 60 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 71.7 bits (168), Expect = 2e-11 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 12/86 (13%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI------GLNADYS 449 ++RED++IT+KLWN +H +V A SL+ LGLDY+DLYL+HWP G + Sbjct: 86 IRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPNFHPPGCDVSSR 145 Query: 450 HSD------VDFMETWRGLEDAQRMG 509 D +FM+TWR LE G Sbjct: 146 SPDARPYIHAEFMKTWRQLETLHDRG 171 Score = 48.8 bits (111), Expect = 2e-04 Identities = 26/65 (40%), Positives = 39/65 (60%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++P + +G MPAIG+GT+ G D + ++ V A ++GYRHFD A+VY Sbjct: 15 KIPQRTLASGARMPAIGMGTF-GSDH-----AAPGEVAASVYAAAELGYRHFDCAAVYSN 68 Query: 241 EQEIG 255 E+EIG Sbjct: 69 EREIG 73 Score = 43.6 bits (98), Expect = 0.006 Identities = 18/62 (29%), Positives = 36/62 (58%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+V+ IG SN +L+ +L++ ++P ++E+H Q + ++ + +V +GY P Sbjct: 171 GLVRHIGTSNMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCPL 230 Query: 686 GS 691 GS Sbjct: 231 GS 232 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 71.7 bits (168), Expect = 2e-11 Identities = 34/94 (36%), Positives = 54/94 (57%), Gaps = 16/94 (17%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI------------- 428 V+RE++F+++K+WNT H R Q I++ L+ Y+DL ++HWP Sbjct: 70 VRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAEDEPPGERGL 129 Query: 429 ---GLNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 G N +SDVD++ETW+ LEDA R G +++ Sbjct: 130 WPRGANGKMRYSDVDYLETWKALEDAHRSGKIRS 163 Score = 52.0 bits (119), Expect = 2e-05 Identities = 22/63 (34%), Positives = 43/63 (68%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G ++ IGL+NFN Q+E+V +G IKP +Q+E++ Q+E+ +FC+ +G+++ + Sbjct: 158 SGKIRSIGLANFNIGQVEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFML 217 Query: 683 FGS 691 G+ Sbjct: 218 TGN 220 Score = 34.7 bits (76), Expect = 2.8 Identities = 19/61 (31%), Positives = 37/61 (60%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++ +N+G +MP IG GT+ +N + ++RD A++ GYRH D+A ++ ++E Sbjct: 6 TVTLNSGYEMPVIGYGTWQ-LPKNLAAE----RVRD----ALEAGYRHIDSALSFKNQEE 56 Query: 250 I 252 + Sbjct: 57 V 57 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 71.7 bits (168), Expect = 2e-11 Identities = 34/73 (46%), Positives = 45/73 (61%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440 + I+EG+VKRE++FI TKLWNT H + V A + LK GL+Y DLYL+H+PI L Sbjct: 61 INKAIKEGLVKREELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPL-- 118 Query: 441 DYSHSDVDFMETW 479 Y V + W Sbjct: 119 QYVDPAVSYPPEW 131 Score = 51.2 bits (117), Expect = 3e-05 Identities = 23/60 (38%), Positives = 37/60 (61%) Frame = +2 Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 + + IG++NFN Q + +L IKP +QIE+H Q+ +V++ Q +G+ V YS FG Sbjct: 161 LTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQEQGIQVTAYSSFG 220 Score = 33.1 bits (72), Expect = 8.5 Identities = 15/39 (38%), Positives = 22/39 (56%) Frame = +1 Query: 142 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 G K + K + + +AI +GYR FD A Y E E+G+ Sbjct: 21 GCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGR 59 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 71.7 bits (168), Expect = 2e-11 Identities = 32/59 (54%), Positives = 46/59 (77%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 +K +E+GV KREDIF+TTK+W T H R E + ++ SL++LGLDY+D+ L+HWP+ LN Sbjct: 89 IKRAMEKGV-KREDIFVTTKIWVTYHDRVE--ENLDMSLERLGLDYVDMLLIHWPVPLN 144 Score = 60.1 bits (139), Expect = 6e-08 Identities = 27/63 (42%), Positives = 40/63 (63%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IG+SNF+ LE +LKE + P Q+E+H Q E++EFC+ +V+ +SPF Sbjct: 182 GKTKSIGVSNFSIPYLEELLKEAEVVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPF 241 Query: 686 GSL 694 GS+ Sbjct: 242 GSV 244 Score = 41.9 bits (94), Expect = 0.018 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Frame = +1 Query: 55 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVGYRHFDTASV 231 TM +NNG+ +PAIGLGT+ KS +++ V A+ + GYRH DTA Sbjct: 28 TMTSLDFTLNNGKTIPAIGLGTW---------KSTTEEVAGAVECALTEGGYRHIDTAFN 78 Query: 232 YETEQEIG 255 Y E +G Sbjct: 79 YRNEDAVG 86 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 71.3 bits (167), Expect = 3e-11 Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 9/93 (9%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434 A+ I G V+R+D+F+T+KLW++ H + A+ +LK +GLDY+D YL+HWPI L Sbjct: 61 ALGQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIKLK 118 Query: 435 --------NADYSHSDVDFMETWRGLEDAQRMG 509 D D+ ETW+G+E MG Sbjct: 119 PGVSEPIPKEDEFEKDLGIEETWQGMERCLEMG 151 Score = 51.2 bits (117), Expect = 3e-05 Identities = 24/75 (32%), Positives = 42/75 (56%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 670 RC G+ + IG+SNF+ +++ +L ++ P Q+E+H Q+++ + C+ + V Sbjct: 146 RCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCEENNIHVS 205 Query: 671 GYSPFGSLVARHGST 715 GYSP G GST Sbjct: 206 GYSPLGGPGNCWGST 220 Score = 43.6 bits (98), Expect = 0.006 Identities = 22/61 (36%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLR-DVVMRAIDVGYRHFDTASVYETEQEI 252 ++ G +P +G+GTY KD++ V +AI +GYRHFDTA +Y +E+ + Sbjct: 7 RLRCGETIPLLGMGTYC--------PQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEAL 58 Query: 253 G 255 G Sbjct: 59 G 59 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 71.3 bits (167), Expect = 3e-11 Identities = 31/63 (49%), Positives = 48/63 (76%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + +K I+E +VKRE++F+TTK+W T + R V+++++ SLK L LDY+DL L+HWP+ L Sbjct: 57 KGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSL 114 Query: 435 NAD 443 AD Sbjct: 115 LAD 117 Score = 49.6 bits (113), Expect = 9e-05 Identities = 26/63 (41%), Positives = 37/63 (58%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S K+N+G +PA+GLGT + D + +VV AI GYRH DTA +Y +E + Sbjct: 6 SFKLNDGHSIPALGLGT-----------ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVD 54 Query: 250 IGK 258 +GK Sbjct: 55 VGK 57 Score = 48.4 bits (110), Expect = 2e-04 Identities = 23/63 (36%), Positives = 37/63 (58%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G K IG+SN ++ L+R+L + P Q E+H QK+ +EF + G++V +SP Sbjct: 155 SGRTKSIGVSNVSEVYLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSP 214 Query: 683 FGS 691 GS Sbjct: 215 LGS 217 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 71.3 bits (167), Expect = 3e-11 Identities = 33/67 (49%), Positives = 42/67 (62%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 E V I + R+D+FITTKLWN +H E A AI +SL KL LD +DLYL+HWP Sbjct: 54 EGVGAAIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPA 113 Query: 435 NADYSHS 455 +Y H+ Sbjct: 114 ADNYVHA 120 Score = 46.8 bits (106), Expect = 6e-04 Identities = 25/66 (37%), Positives = 37/66 (56%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M VPS+ +N+G +P +G G + V D Q V A++VGYRH DTA++Y Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVFK-------VPPADTQR--AVEEALEVGYRHIDTAAIYG 51 Query: 238 TEQEIG 255 E+ +G Sbjct: 52 NEEGVG 57 Score = 39.9 bits (89), Expect = 0.074 Identities = 19/63 (30%), Positives = 33/63 (52%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G+ + IG+SN LER++ + P QIE+H Q+E+ ++ + V + + Sbjct: 129 AAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWG 188 Query: 680 PFG 688 P G Sbjct: 189 PLG 191 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 71.3 bits (167), Expect = 3e-11 Identities = 31/58 (53%), Positives = 44/58 (75%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 EA+K +E+G +KRED+FITTK+W EV +++N+SLK LGL+Y+DL L HWP+ Sbjct: 79 EAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPL 134 Score = 56.4 bits (130), Expect = 8e-07 Identities = 25/60 (41%), Positives = 38/60 (63%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 691 V+ IG+SNF+ + LER++KE +KP Q+E H Q E+ +FC +++ YSP GS Sbjct: 186 VRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGS 245 Score = 44.0 bits (99), Expect = 0.005 Identities = 25/60 (41%), Positives = 32/60 (53%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG +PA+GLGT K + + V AI GYRH DTA YETE +G+ Sbjct: 27 LNNGVRIPALGLGT-------ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGE 79 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 70.9 bits (166), Expect = 3e-11 Identities = 30/62 (48%), Positives = 44/62 (70%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+ + IGLSNFN++Q++R+L IKP +QIE H+ Q E+V+FC++ G+ V YSP Sbjct: 154 GLARNIGLSNFNQRQIQRILDNCQIKPANLQIENHIYLQQPELVKFCKANGITVTAYSPL 213 Query: 686 GS 691 GS Sbjct: 214 GS 215 Score = 47.6 bits (108), Expect = 4e-04 Identities = 23/62 (37%), Positives = 35/62 (56%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 + NG MPA+G GT+ ++ D+++ + A++ GYRH DTA VY E+ I Sbjct: 7 ITFENGTTMPALGFGTW---------RASDEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57 Query: 253 GK 258 GK Sbjct: 58 GK 59 Score = 41.9 bits (94), Expect = 0.018 Identities = 21/57 (36%), Positives = 35/57 (61%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 + +K ++ G V R+++FI TKL R + V + + +SL L L+Y+DLY +H P Sbjct: 59 KVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVP 115 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 70.9 bits (166), Expect = 3e-11 Identities = 30/63 (47%), Positives = 44/63 (69%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + ++ I G+VKRED+F+ +K W T R E+ ++ SLK LGLDY+DLYL+HWPI + Sbjct: 58 QGIREAISSGIVKREDLFVVSKCWATYTTRCELG--LDQSLKLLGLDYVDLYLVHWPILM 115 Query: 435 NAD 443 N + Sbjct: 116 NPE 118 Score = 64.1 bits (149), Expect = 4e-09 Identities = 28/64 (43%), Positives = 42/64 (65%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G K +G+SN++K LE++L T P Q+E H Q Q+E+V+FC+ +G+ +M YS Sbjct: 152 ATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYS 211 Query: 680 PFGS 691 P GS Sbjct: 212 PLGS 215 Score = 43.2 bits (97), Expect = 0.008 Identities = 25/60 (41%), Positives = 34/60 (56%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +N G +PA GLGT+ G GV+K + V+ AI GYR D A VY E+E+G+ Sbjct: 8 LNTGAKIPAFGLGTWQG--DKGVIK-------EAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 70.9 bits (166), Expect = 3e-11 Identities = 39/101 (38%), Positives = 56/101 (55%), Gaps = 12/101 (11%) Frame = +3 Query: 255 EAVKMKIEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 EA+K + G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117 Query: 432 L---------NAD--YSHSDVDFMETWRGLEDAQRMG*LKA 521 NAD + + ETW+ LE G ++A Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158 Score = 66.1 bits (154), Expect = 1e-09 Identities = 26/64 (40%), Positives = 42/64 (65%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G+V+ +GLSNFN +Q++ +L +++P +Q+E H Q E++ CQ+ G+ V YS Sbjct: 152 AKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYS 211 Query: 680 PFGS 691 P GS Sbjct: 212 PLGS 215 Score = 48.0 bits (109), Expect = 3e-04 Identities = 26/67 (38%), Positives = 38/67 (56%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51 Query: 238 TEQEIGK 258 E EIG+ Sbjct: 52 NEPEIGE 58 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 70.9 bits (166), Expect = 3e-11 Identities = 37/97 (38%), Positives = 56/97 (57%), Gaps = 8/97 (8%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431 EA+K I G+V R+D+F+T+KLW T++ V A+ SLK L L+Y+DLYL+HWP+ Sbjct: 67 EALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSS 126 Query: 432 ----LNADYSHSDV---DFMETWRGLEDAQRMG*LKA 521 + D+ D W +E+ Q++G KA Sbjct: 127 QPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKA 163 Score = 60.1 bits (139), Expect = 6e-08 Identities = 25/63 (39%), Positives = 42/63 (66%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ K IG+SNF+ ++L+ +L TI+P Q+E++L QK++ EFC+ G++V Sbjct: 155 CQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTA 214 Query: 674 YSP 682 +SP Sbjct: 215 FSP 217 Score = 45.2 bits (102), Expect = 0.002 Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 3/73 (4%) Frame = +1 Query: 49 ASTMEVPSLKMNNG---RDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFD 219 A+ +E+P++ N + MP +G+G+ F + K ++ ++ A+ GYRHFD Sbjct: 2 AAAIEIPTIVFPNSSAQQRMPVVGMGSAPDF-------TCKKDTKEAIIEAVKQGYRHFD 54 Query: 220 TASVYETEQEIGK 258 TA+ Y +EQ +G+ Sbjct: 55 TAAAYGSEQALGE 67 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 70.1 bits (164), Expect = 6e-11 Identities = 36/89 (40%), Positives = 50/89 (56%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EA+ I +G+VKRE++F+T+K+W + AI SL++L LDY+DLYL+H P Sbjct: 57 EAILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN- 115 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D WR +E A R G LKA Sbjct: 116 ---------DVFGAWRAMESAYRSGQLKA 135 Score = 39.9 bits (89), Expect = 0.074 Identities = 22/61 (36%), Positives = 34/61 (55%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G +K IG+SNF+ QL + + IKP QIEV+ K+ + + GV V ++P Sbjct: 130 SGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDITYFSQYGVQVEAWAP 189 Query: 683 F 685 F Sbjct: 190 F 190 Score = 34.7 bits (76), Expect = 2.8 Identities = 20/58 (34%), Positives = 30/58 (51%) Frame = +1 Query: 85 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +G +MP +G G + + G K V+ AI GYR DTA+ Y E+E+G+ Sbjct: 8 SGIEMPLLGFGVFQ-VQEKGAAKQ-------AVLDAIKTGYRLIDTAASYGNEREVGE 57 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 70.1 bits (164), Expect = 6e-11 Identities = 28/47 (59%), Positives = 39/47 (82%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 +KREDIFIT+KLWN+QH V +A+++ L +L LDY+DLYL+HWP+ Sbjct: 71 LKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPV 117 Score = 43.6 bits (98), Expect = 0.006 Identities = 20/57 (35%), Positives = 31/57 (54%) Frame = +2 Query: 521 IGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 691 +G+SN LE ++ + P QIE H E++E+CQ +G+ V YS FG+ Sbjct: 165 VGVSNHMIPHLEAIINATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGN 221 Score = 41.9 bits (94), Expect = 0.018 Identities = 19/60 (31%), Positives = 34/60 (56%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +N+G +P +G GT+ +S Q+ D V A+ GYRH D A++Y+ ++E+ + Sbjct: 9 LNSGAQIPQLGFGTW---------QSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAE 59 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 70.1 bits (164), Expect = 6e-11 Identities = 37/94 (39%), Positives = 57/94 (60%), Gaps = 11/94 (11%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG------- 431 I + V RE+IFIT KLWNT+H +V A++ +L+ LG+ Y+DLYLMHWP Sbjct: 61 IRKSGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKW 120 Query: 432 --LNAD--YSHSDVDFMETWRGLEDAQRMG*LKA 521 LN D + +++D++ T+R +E G ++A Sbjct: 121 FPLNDDGVFDLANIDYITTYRAMEKLLATGKVRA 154 Score = 65.3 bits (152), Expect = 2e-09 Identities = 30/76 (39%), Positives = 48/76 (63%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G V+ IG+SNFN ++LE +L + ++ P QIE H Q ++++FCQS+G+++ YS Sbjct: 148 ATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDLLQFCQSKGILIEAYS 207 Query: 680 PFGSLVARHGSTVEGP 727 P G+ TV+ P Sbjct: 208 PLGNNQTGEPRTVDDP 223 Score = 42.7 bits (96), Expect = 0.010 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = +1 Query: 58 MEVPS-LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 M +PS +N G +PA+G GT+ ++K ++ + V A+ GYRH D A++Y Sbjct: 1 MSLPSHFTINTGAKIPAVGFGTW---------QAKPLEVENAVEVALREGYRHIDCAAIY 51 Query: 235 ETEQEIG 255 E E+G Sbjct: 52 RNETEVG 58 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 69.7 bits (163), Expect = 8e-11 Identities = 31/81 (38%), Positives = 50/81 (61%), Gaps = 2/81 (2%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 I+ V R++I++T KLWNT HR V +AI S+ LG++Y+DLYL+H+P+ + Sbjct: 106 IKASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPETRD 165 Query: 453 SD--VDFMETWRGLEDAQRMG 509 D ++TW+ +E+ R G Sbjct: 166 VDNNTSLIDTWKAMEELVRAG 186 Score = 45.6 bits (103), Expect = 0.001 Identities = 21/68 (30%), Positives = 37/68 (54%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+ + IG SNF + + ++LK +I+P A + E H Q+ V+F + E + V+ SP Sbjct: 186 GLTRNIGFSNFAPKDINKILKIASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAASPL 245 Query: 686 GSLVARHG 709 + +G Sbjct: 246 ANTNPTYG 253 Score = 43.6 bits (98), Expect = 0.006 Identities = 28/67 (41%), Positives = 35/67 (52%), Gaps = 1/67 (1%) Frame = +1 Query: 61 EVPSLKMNNG-RDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 E+P N RD+PA GLGT+L GVV V A+ GYRH DTA ++ Sbjct: 47 EMPEFNKNETVRDIPAFGLGTWLA--GKGVVVP-------AVEYALKGGYRHIDTALIWR 97 Query: 238 TEQEIGK 258 E E+GK Sbjct: 98 NEDEVGK 104 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 69.7 bits (163), Expect = 8e-11 Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 9/98 (9%) Frame = +3 Query: 255 EAVKMKIEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 EA+ G+V RE++F+TTKLW TQ V ++ +SL+ L ++Y+DLYL+HWPI Sbjct: 64 EAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPIS 123 Query: 432 LN-----ADYSHSDV---DFMETWRGLEDAQRMG*LKA 521 + D DF WR +E+ R+G KA Sbjct: 124 VKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKA 161 Score = 53.6 bits (123), Expect = 6e-06 Identities = 24/65 (36%), Positives = 39/65 (60%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ K IG+SNF + L+++L TI P Q+E++ Q+ + E+C ++G+ V Sbjct: 153 CHRLGLAKAIGVSNFTTKHLDKLLAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAA 212 Query: 674 YSPFG 688 YSP G Sbjct: 213 YSPLG 217 Score = 48.0 bits (109), Expect = 3e-04 Identities = 27/70 (38%), Positives = 43/70 (61%) Frame = +1 Query: 49 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228 A+ EV +L+ GR MPA+G+GT + S + + R + A++VG+RHFDTA+ Sbjct: 2 AAVPEV-ALRHGAGRPMPAVGVGT-----ADSAATSPETK-RGAALAALEVGFRHFDTAA 54 Query: 229 VYETEQEIGK 258 +Y TE +G+ Sbjct: 55 LYGTEAPLGE 64 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 69.3 bits (162), Expect = 1e-10 Identities = 31/57 (54%), Positives = 39/57 (68%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 EA++ G + RE+IF+TTKLWNT HR V A SL +LGLDY+DLYL+H P Sbjct: 64 EALRAGRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTP 120 Score = 50.4 bits (115), Expect = 5e-05 Identities = 20/61 (32%), Positives = 37/61 (60%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G + IGLS+ + +L + + IKP +Q+E H + E++EFC+ G+V++ ++P Sbjct: 160 GRCRAIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEFCKRNGIVLLAFAPL 219 Query: 686 G 688 G Sbjct: 220 G 220 Score = 33.1 bits (72), Expect = 8.5 Identities = 17/54 (31%), Positives = 28/54 (51%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +PA+G GT + + ++D A+ G+RHFD A Y E+E+G+ Sbjct: 20 IPALGFGTLIADPALTITATRD---------ALAAGFRHFDCAERYRNEREVGE 64 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 69.3 bits (162), Expect = 1e-10 Identities = 33/82 (40%), Positives = 48/82 (58%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 I E V R+ IF+T+KLWN+ E A ++L KLGLDY+DLYL+HWP Sbjct: 69 IRESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPA-------- 120 Query: 453 SDVDFMETWRGLEDAQRMG*LK 518 ++++WR +ED + G +K Sbjct: 121 --PGYLDSWRAMEDLYKAGKIK 140 Score = 56.0 bits (129), Expect = 1e-06 Identities = 25/61 (40%), Positives = 38/61 (62%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G +K IG+SNFN+ Q+ +L GT+KP QIE H Q +M + +S+G++ +SP Sbjct: 137 GKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAYLESQGILHEAWSPL 196 Query: 686 G 688 G Sbjct: 197 G 197 Score = 47.2 bits (107), Expect = 5e-04 Identities = 24/66 (36%), Positives = 38/66 (57%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++P L MNNG +P +GLG + V ++D ++ + A+ GYRH DTA+ Y Sbjct: 10 DIPDLPMNNGHQIPQLGLGVFQ------VDNAEDT--KNAIKWALAAGYRHIDTAAYYGN 61 Query: 241 EQEIGK 258 EQ +G+ Sbjct: 62 EQWVGE 67 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 68.9 bits (161), Expect = 1e-10 Identities = 33/94 (35%), Positives = 53/94 (56%), Gaps = 10/94 (10%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 434 A+ + G ++R+D+++T+KLWN H +V A+ +L L LD +DLYL+HWP+ L Sbjct: 57 ALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQ 116 Query: 435 -NADYSHSDVDFM--------ETWRGLEDAQRMG 509 D+ S DF+ ETW +E ++ G Sbjct: 117 PEVDFPESPDDFVSPEAVPLTETWAAMEALKKDG 150 Score = 56.8 bits (131), Expect = 6e-07 Identities = 23/63 (36%), Positives = 40/63 (63%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G+V+ IG+SNF+ L+ +L G ++P+ Q+E+H Q E+V F ++ + + YSP Sbjct: 149 DGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVEMHPYLPQPELVSFAEAHNIPITAYSP 208 Query: 683 FGS 691 GS Sbjct: 209 LGS 211 Score = 48.0 bits (109), Expect = 3e-04 Identities = 24/62 (38%), Positives = 35/62 (56%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S+ NG +MP IGLGT+ KS ++ + V A++ GYRH D A +Y+ E E Sbjct: 3 SISFENGDEMPMIGLGTW---------KSPPGEVYEAVTTALEAGYRHVDCAPIYKNETE 53 Query: 250 IG 255 +G Sbjct: 54 VG 55 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 68.9 bits (161), Expect = 1e-10 Identities = 38/81 (46%), Positives = 49/81 (60%), Gaps = 7/81 (8%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-----GLNADYSH 452 + RED+FI +KL T HR V + SL++LGLDY+DLYLMH P+ G D S Sbjct: 66 INREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSGDGNDRSE 125 Query: 453 SD--VDFMETWRGLEDAQRMG 509 D V +ETW+ LE+ QR G Sbjct: 126 IDDEVTPLETWKALEECQRKG 146 Score = 65.3 bits (152), Expect = 2e-09 Identities = 26/65 (40%), Positives = 43/65 (66%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+V+ IG+SNFN++QL ++ G+I+P Q+E + Q ++ +FC EG+++M Sbjct: 142 CQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVKLRKFCNREGILIMA 201 Query: 674 YSPFG 688 YSP G Sbjct: 202 YSPLG 206 Score = 46.0 bits (104), Expect = 0.001 Identities = 26/62 (41%), Positives = 33/62 (53%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 L +NNG +P IGLGTY +GV K A++ GYR DTA VY EQ + Sbjct: 2 LALNNGHSIPPIGLGTYKITGSDGVAAIKS---------AVEFGYRLIDTAFVYNNEQVV 52 Query: 253 GK 258 G+ Sbjct: 53 GQ 54 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 68.5 bits (160), Expect = 2e-10 Identities = 35/101 (34%), Positives = 57/101 (56%), Gaps = 12/101 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 425 + +K KI++G +KRED+F+T+KLW T + V + SL LGL Y+DL+L+H P Sbjct: 60 DGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSA 119 Query: 426 IGLNADYSHSD---------VDFMETWRGLEDAQRMG*LKA 521 +G + D +D+++TWR +E G ++A Sbjct: 120 VGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRA 160 Score = 59.3 bits (137), Expect = 1e-07 Identities = 28/63 (44%), Positives = 40/63 (63%), Gaps = 1/63 (1%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDA-IQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+V+ IG+SNF Q++RVL P A +Q+E H Q E++EFC+ +G+ V YSP Sbjct: 156 GLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSP 215 Query: 683 FGS 691 GS Sbjct: 216 LGS 218 Score = 40.3 bits (90), Expect = 0.056 Identities = 21/56 (37%), Positives = 32/56 (57%) Frame = +1 Query: 88 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 GR +P +G GT+ + K +++ V+ AID GYRH D AS+Y E+ +G Sbjct: 13 GRKLPLLGFGTW---------QIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVG 59 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 68.5 bits (160), Expect = 2e-10 Identities = 36/100 (36%), Positives = 57/100 (57%), Gaps = 11/100 (11%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A + K +G +KRED+F T+KLWNT H+ V A+ +L L +DY+DLYL+H P+ Sbjct: 85 QAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSF 144 Query: 435 ---------NAD--YSHSDVDFMETWRGLEDAQRMG*LKA 521 N D + D ++TW+ LE+ + G +K+ Sbjct: 145 KPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKS 184 Score = 64.5 bits (150), Expect = 3e-09 Identities = 32/68 (47%), Positives = 45/68 (66%), Gaps = 2/68 (2%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVV 667 C G+VK IG+SNFN++QLE +L + +K P QIE H QK+M+EFC+S+ +VV Sbjct: 176 CRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVV 235 Query: 668 MGYSPFGS 691 + Y GS Sbjct: 236 VAYGVLGS 243 Score = 37.9 bits (84), Expect = 0.30 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 15/78 (19%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFD---------------QNGVVKSKDKQLRDVVMRAIDVG 204 S+++++GR MP + GT+ F ++G KS +R A+D+G Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67 Query: 205 YRHFDTASVYETEQEIGK 258 YRH D A +Y +E +G+ Sbjct: 68 YRHVDGAFLYSSETGVGQ 85 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 68.5 bits (160), Expect = 2e-10 Identities = 30/58 (51%), Positives = 41/58 (70%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 A+K I+EG+V+RE++F+TTKLW + +A SLKKL L+YIDLYL+H P G Sbjct: 59 AIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG 116 Score = 44.4 bits (100), Expect = 0.003 Identities = 23/67 (34%), Positives = 37/67 (55%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M+VP + +NNG +MP +G G + + ++ + V AI VGYR DTA+ Y Sbjct: 1 MQVPKVTLNNGVEMPILGYGVF---------QIPPEKTEECVYEAIKVGYRLIDTAASYM 51 Query: 238 TEQEIGK 258 E+ +G+ Sbjct: 52 NEEGVGR 58 Score = 39.1 bits (87), Expect = 0.13 Identities = 19/61 (31%), Positives = 34/61 (55%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G+V+ IG+SNF +L ++ I P QIE+H ++E +EF ++ + + P Sbjct: 131 DGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQPEAWGP 190 Query: 683 F 685 F Sbjct: 191 F 191 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 68.5 bits (160), Expect = 2e-10 Identities = 31/95 (32%), Positives = 57/95 (60%), Gaps = 10/95 (10%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A++ I+ + R +++IT+KLW+ H + V A++ SL+ LG+DY++LYL+HWP+G+ Sbjct: 74 DAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGI 133 Query: 435 NADYSHSD-VD---------FMETWRGLEDAQRMG 509 + + ++ VD ETW +E + G Sbjct: 134 RPEKTFAESVDDLLTPEESPISETWEAMESTRDKG 168 Score = 54.8 bits (126), Expect = 2e-06 Identities = 23/63 (36%), Positives = 40/63 (63%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+ K IG+SNF ++L++++ KP+ Q+E H Q ++E+C SE +++ YSP Sbjct: 168 GLTKHIGVSNFTVKKLQQLVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYSPL 227 Query: 686 GSL 694 GS+ Sbjct: 228 GSM 230 Score = 49.2 bits (112), Expect = 1e-04 Identities = 29/67 (43%), Positives = 39/67 (58%) Frame = +1 Query: 55 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 TM+ SL +NG MP +GLGT KS+ +Q+ V AI +GYRH D AS+Y Sbjct: 18 TMQYASL--SNGDRMPLLGLGTG---------KSESRQVYKSVREAIKIGYRHIDCASIY 66 Query: 235 ETEQEIG 255 E+E+G Sbjct: 67 GNEEEVG 73 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 68.1 bits (159), Expect = 2e-10 Identities = 30/62 (48%), Positives = 42/62 (67%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IGLSNFN Q++R+LK +K +QIE+H+ QKE+V+FC+ E + + YSP Sbjct: 155 GRTKAIGLSNFNISQIKRILKNTKMKISMLQIELHVYFQQKELVKFCKQENIPITAYSPL 214 Query: 686 GS 691 GS Sbjct: 215 GS 216 Score = 51.6 bits (118), Expect = 2e-05 Identities = 26/59 (44%), Positives = 37/59 (62%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 + +K + +KR DIFI TKL +R +V + I SL+ L L+Y+DLYL+H PIG Sbjct: 58 DVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIG 116 Score = 50.0 bits (114), Expect = 7e-05 Identities = 26/66 (39%), Positives = 40/66 (60%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 ME ++ + NG MP IG GT+ ++++K+L D + A++ GYRH DTA+ YE Sbjct: 1 MEKNTILLPNGELMPIIGFGTW---------QAQEKELEDALNIALEAGYRHIDTATSYE 51 Query: 238 TEQEIG 255 E+ IG Sbjct: 52 NEKVIG 57 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 68.1 bits (159), Expect = 2e-10 Identities = 40/90 (44%), Positives = 51/90 (56%), Gaps = 1/90 (1%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQA-INDSLKKLGLDYIDLYLMHWPIG 431 EAV+ I EG+ RE++FIT+KLW ++A A I SLKK GL+Y DLYL+H + Sbjct: 62 EAVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR 121 Query: 432 LNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D+ WR LEDA G LKA Sbjct: 122 ----------DYFSAWRALEDAYEEGKLKA 141 Score = 33.9 bits (74), Expect = 4.8 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Frame = +1 Query: 142 GVVKSKDKQL-RDVVMRAIDVGYRHFDTASVYETEQEIGK 258 GV + DK + + V+ AI GYR DTA+VY E +G+ Sbjct: 23 GVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGE 62 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 68.1 bits (159), Expect = 2e-10 Identities = 30/88 (34%), Positives = 51/88 (57%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 A+K +EE KREDIF+T+K W T+ + A ++ ++ +DY+DLYL+HWP Sbjct: 62 AIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYA 121 Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D + + +TW+ + + + G +KA Sbjct: 122 FDDDWENTN-RQTWKAMTEIYKSGRVKA 148 Score = 44.4 bits (100), Expect = 0.003 Identities = 25/58 (43%), Positives = 31/58 (53%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 +K+NNG +P G GTY DQN S V A+ GYRH DTA+ YE E+ Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNEAYNS--------VRLALKNGYRHIDTAAFYENEK 57 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 68.1 bits (159), Expect = 2e-10 Identities = 37/89 (41%), Positives = 47/89 (52%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + V I E V R DIF+TTKLWN H A S + LG++Y+DLYL+HWP G Sbjct: 56 KGVGQGISECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP-GP 114 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 N Y +ETWR E M ++A Sbjct: 115 NRSY-------IETWRAFEKLYEMKKVRA 136 Score = 43.6 bits (98), Expect = 0.006 Identities = 19/59 (32%), Positives = 31/59 (52%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 V+ IG+SNF L+ +L T+ P Q+E+H QK + +C + + V + P G Sbjct: 134 VRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPHFQQKALRAYCAEKNIAVTAWRPLG 192 Score = 41.5 bits (93), Expect = 0.024 Identities = 22/60 (36%), Positives = 34/60 (56%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 ++NG +P +G+GT+ D N VV K A++ GYRH DTA Y+ E+ +G+ Sbjct: 10 LSNGVQVPQLGIGTWEAKDGNEVVNIK---------WAVNAGYRHVDTAHYYKNEKGVGQ 60 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 68.1 bits (159), Expect = 2e-10 Identities = 27/47 (57%), Positives = 35/47 (74%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 V R+ IFIT+KLWNT H V +A+N +LK L DY+DLYL+HWP+ Sbjct: 66 VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPV 112 Score = 50.8 bits (116), Expect = 4e-05 Identities = 25/62 (40%), Positives = 38/62 (61%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 + K+N+G ++PAIGLGT+L SK ++ + V A+ GYRH D A+ Y+ E E Sbjct: 6 TFKLNSGYNIPAIGLGTWL---------SKPHEVENAVEAALRAGYRHIDAAACYQNENE 56 Query: 250 IG 255 +G Sbjct: 57 VG 58 Score = 45.2 bits (102), Expect = 0.002 Identities = 20/72 (27%), Positives = 39/72 (54%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 691 ++ IG+SNF + +++ +LK I P QIE H Q + ++ + + ++ + YSP G+ Sbjct: 154 IRSIGISNFTQDKIDDLLKTAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLGN 213 Query: 692 LVARHGSTVEGP 727 + V+ P Sbjct: 214 NIYNAPRVVDDP 225 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 68.1 bits (159), Expect = 2e-10 Identities = 31/69 (44%), Positives = 43/69 (62%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 V RE+IF+T+KLWNT H V +A++ SL L DY+DLYL+HWP+ YS + + Sbjct: 66 VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFR--YSTTTIQP 123 Query: 468 METWRGLED 494 + GL D Sbjct: 124 VNEQTGLID 132 Score = 60.5 bits (140), Expect = 5e-08 Identities = 28/74 (37%), Positives = 45/74 (60%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G V+ IG+SNF ++++E +LK I P QIE H Q++++E+ +G+VV GYSP Sbjct: 152 GKVRSIGVSNFTREKIEELLKTAKITPAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPL 211 Query: 686 GSLVARHGSTVEGP 727 G+ + V+ P Sbjct: 212 GNNIYNIPRAVDDP 225 Score = 60.1 bits (139), Expect = 6e-08 Identities = 29/62 (46%), Positives = 40/62 (64%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 + K+N G DMPA+GLGT+ +SK ++RD V+ A+ GYRH D A+VY EQE Sbjct: 6 TFKLNTGYDMPAVGLGTW---------QSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQE 56 Query: 250 IG 255 +G Sbjct: 57 VG 58 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 68.1 bits (159), Expect = 2e-10 Identities = 38/100 (38%), Positives = 56/100 (56%), Gaps = 15/100 (15%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 425 EA+ + G+VKRE++FITTK+WN+ H V +A +SL+KL +DY+DLYL+H+P Sbjct: 56 EALAEAFKTGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPT 113 Query: 426 ----IGLNADYSHSD--------VDFMETWRGLEDAQRMG 509 IG A D + +TW G+E +G Sbjct: 114 KHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLG 153 Score = 48.0 bits (109), Expect = 3e-04 Identities = 21/63 (33%), Positives = 42/63 (66%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++ +++G +MP IGLG + + + +L++V++ AI +GYRHFD A+ Y++E + Sbjct: 3 TVTLSSGYEMPVIGLGLW---------RLEKDELKEVILNAIKIGYRHFDCAAHYKSEAD 53 Query: 250 IGK 258 +G+ Sbjct: 54 VGE 56 Score = 44.4 bits (100), Expect = 0.003 Identities = 22/65 (33%), Positives = 31/65 (47%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+V+ IGLSN+ L IKP Q E H + +V+FC GV+ ++P Sbjct: 153 GLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPL 212 Query: 686 GSLVA 700 G A Sbjct: 213 GGAAA 217 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 68.1 bits (159), Expect = 2e-10 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 10/99 (10%) Frame = +3 Query: 255 EAVKMKIEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 EAV + G++ R D+F+T+K+W + V A ++L+ LG+DY+DL L+HWP+ Sbjct: 63 EAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVS 122 Query: 432 L---NADYSH------SDVDFMETWRGLEDAQRMG*LKA 521 L N D+ D WRG+E+ R+G +A Sbjct: 123 LTPGNYDFPFPKEVILPSFDMEGVWRGMEECHRLGLARA 161 Score = 58.0 bits (134), Expect = 3e-07 Identities = 27/73 (36%), Positives = 44/73 (60%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ + IG+SNF+ ++LE++L ++P Q+EV+ Q+ + E C+ EGV + G Sbjct: 153 CHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCG 212 Query: 674 YSPFGSLVARHGS 712 YSP G+ GS Sbjct: 213 YSPLGAKGTPWGS 225 Score = 43.2 bits (97), Expect = 0.008 Identities = 27/70 (38%), Positives = 42/70 (60%) Frame = +1 Query: 49 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228 A+ EVP+ ++ + MP +G+GT F S+D ++RAI++GYRHFDTA Sbjct: 2 ATIPEVPASELI--QTMPRVGMGT-AAFP---FTSSEDTTA--AMLRAIELGYRHFDTAR 53 Query: 229 VYETEQEIGK 258 +Y TE +G+ Sbjct: 54 IYATEGCVGE 63 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 67.7 bits (158), Expect = 3e-10 Identities = 30/57 (52%), Positives = 41/57 (71%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 V+ I++GVVKRE++FI +KLW T H + V A +L L LDY+DLYLMH+P+G Sbjct: 59 VQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMG 115 Score = 56.4 bits (130), Expect = 8e-07 Identities = 27/65 (41%), Positives = 41/65 (63%), Gaps = 2/65 (3%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 676 +G+ K IG+SNFNK Q+E VL + + KP QIE H Q++++ FC+S G+ V + Sbjct: 175 DGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHFCRSRGISVTAF 234 Query: 677 SPFGS 691 + GS Sbjct: 235 ACLGS 239 Score = 50.4 bits (115), Expect = 5e-05 Identities = 28/64 (43%), Positives = 35/64 (54%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +PS+ +N G MP +GLGT+ KS + V AI GYRH DTA VYE E Sbjct: 2 IPSVTLNTGALMPVLGLGTW---------KSGKGVTTEAVKVAIGAGYRHIDTAYVYENE 52 Query: 244 QEIG 255 E+G Sbjct: 53 TEVG 56 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 67.7 bits (158), Expect = 3e-10 Identities = 30/62 (48%), Positives = 43/62 (69%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+ K IG+SNF+K Q+ R+LK I+P QIE H+ Q+++V+FC+SE + V YSP Sbjct: 156 GLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPL 215 Query: 686 GS 691 GS Sbjct: 216 GS 217 Score = 56.4 bits (130), Expect = 8e-07 Identities = 27/59 (45%), Positives = 38/59 (64%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 +K ++ G VKRE++FI TK+ +R EV I SL+ L LDY+DLYL+H P +N Sbjct: 61 LKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTIN 119 Score = 50.4 bits (115), Expect = 5e-05 Identities = 24/62 (38%), Positives = 36/62 (58%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 L NNG MP IG+GT+ ++ D+++ + A++ GYRH DTA VY E+ I Sbjct: 7 LTFNNGEKMPVIGIGTW---------QASDEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57 Query: 253 GK 258 G+ Sbjct: 58 GR 59 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 67.7 bits (158), Expect = 3e-10 Identities = 33/98 (33%), Positives = 57/98 (58%), Gaps = 13/98 (13%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EA+ +G VKRE+++IT+K+WNT+HR + + + +LK+L L+Y+DL L+HW Sbjct: 50 EALSEIFAKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAF 109 Query: 435 NA----DYSHSD---------VDFMETWRGLEDAQRMG 509 + +Y D +D +ETW+ +E+ +G Sbjct: 110 QSREDDEYLPRDETGKIITENIDILETWKAMEECYNLG 147 Score = 40.3 bits (90), Expect = 0.056 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 2/67 (2%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVV 667 C G+ K IG+SNF+ +QLER+ + +K P Q+E H+ Q+ M+++ + + Sbjct: 143 CYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQPMLDYLTQRKMYM 202 Query: 668 MGYSPFG 688 + Y+ G Sbjct: 203 ISYTCLG 209 Score = 34.7 bits (76), Expect = 2.8 Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 1/55 (1%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVGYRHFDTASVYETEQEIGK 258 +P+IGLGT+L D L+ V AI D GYRH D A+ Y+ ++ IG+ Sbjct: 4 IPSIGLGTFLAEDPAA--------LKAAVHSAIEDSGYRHVDCAAYYKNQEIIGE 50 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 67.3 bits (157), Expect = 4e-10 Identities = 28/51 (54%), Positives = 39/51 (76%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 ++E + REDIF+TTKLWN +H + A+ +SL+KL LDY+DLYL+HWP Sbjct: 61 LQETDIPREDIFVTTKLWNDRH--LDARAALTESLEKLQLDYVDLYLIHWP 109 Score = 47.2 bits (107), Expect = 5e-04 Identities = 21/63 (33%), Positives = 38/63 (60%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 P +++ +G MP +GLG++ S D+Q+ + + A+D+GYR DTA++Y E+ Sbjct: 5 PIIRLADGNHMPQLGLGSWA---------SDDQQIAETIHAALDIGYRAIDTAAIYNNEK 55 Query: 247 EIG 255 +G Sbjct: 56 GVG 58 Score = 41.1 bits (92), Expect = 0.032 Identities = 17/59 (28%), Positives = 35/59 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+++ IG+SNF + ++R++ E + P QIE+H Q+++ + + +V +SP Sbjct: 130 GLIRSIGVSNFQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAWNATHNIVTESWSP 188 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 67.3 bits (157), Expect = 4e-10 Identities = 28/47 (59%), Positives = 35/47 (74%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 V R+D+FITTK+WN R +V A SL +LGLDYIDLYL+HWP+ Sbjct: 53 VPRKDLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPV 99 Score = 46.4 bits (105), Expect = 8e-04 Identities = 22/60 (36%), Positives = 33/60 (55%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G IG+SNF + LE + + I P QIE H KE++E+CQ+ + V Y+P Sbjct: 116 SGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQVQAYAP 175 Score = 33.9 bits (74), Expect = 4.8 Identities = 19/53 (35%), Positives = 26/53 (49%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 MP +GLG Y D + D + A+ GYR DTAS Y+ E+ +G Sbjct: 1 MPLLGLGLYKTTDA--------VEAEDAIAAAVQNGYRLLDTASAYKNEEFVG 45 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 67.3 bits (157), Expect = 4e-10 Identities = 28/58 (48%), Positives = 41/58 (70%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 +AV I++ V R +++T+KLWN+ H V +A++ SLK LG DY+DLYLMHWP+ Sbjct: 60 DAVAAGIKKAGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPV 117 Score = 55.6 bits (128), Expect = 1e-06 Identities = 26/62 (41%), Positives = 39/62 (62%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G V+ IG+SNFN ++ V+ E +IKP Q+EV+L +E+ + + GV + YSPF Sbjct: 161 GKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSPF 220 Query: 686 GS 691 GS Sbjct: 221 GS 222 Score = 34.3 bits (75), Expect = 3.7 Identities = 20/68 (29%), Positives = 28/68 (41%) Frame = +1 Query: 49 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228 +S + + NG +P +G GT+ K +Q V AI GYRH D A Sbjct: 4 SSVRRSANFTLANGAQIPKLGFGTW---------KMSKEQATPAVAHAIKTGYRHIDCAW 54 Query: 229 VYETEQEI 252 Y E + Sbjct: 55 AYRNEDAV 62 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 66.9 bits (156), Expect = 6e-10 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 15/100 (15%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 E +K +G +KRED+FITTKLW T HR+ V ++++L +L L Y+DL+L+H PI Sbjct: 49 ETLKEIFAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAF 108 Query: 435 NA---------------DYSHSDVDFMETWRGLEDAQRMG 509 + + +D +ET+ +E+ Q+ G Sbjct: 109 KSLPAKDGTMMPKDEKGKIQYEQIDILETYHAMEECQKKG 148 Score = 52.4 bits (120), Expect = 1e-05 Identities = 22/65 (33%), Positives = 39/65 (60%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ + IG+SNF+ +QLER+ IKP A Q+E ++ K ++ +C+S + +M Sbjct: 144 CQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVECNIYRQFKPLLSYCESHNIYLMA 203 Query: 674 YSPFG 688 ++ G Sbjct: 204 HTTIG 208 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 66.9 bits (156), Expect = 6e-10 Identities = 36/81 (44%), Positives = 50/81 (61%) Frame = +3 Query: 276 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 455 +E V R +IFIT+KLW+ H + A AI DSLKKL +DY+D+YLMH P + A+ Sbjct: 79 KENNVPRSEIFITSKLWDADHDKA--AAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKR-- 134 Query: 456 DVDFMETWRGLEDAQRMG*LK 518 +E W+ LE+A G +K Sbjct: 135 ----LEAWKALEEAVDAGKIK 151 Score = 49.2 bits (112), Expect = 1e-04 Identities = 24/59 (40%), Positives = 35/59 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G +K IG+SNF+ ++L+ +L IKP QIE H +E+ E C S G+ + YSP Sbjct: 148 GKIKTIGVSNFDVEELDHLLANCRIKPAVNQIESHPFFAHEELREACISRGIHIQAYSP 206 Score = 42.7 bits (96), Expect = 0.010 Identities = 20/62 (32%), Positives = 32/62 (51%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 +K+NNG+++P + LG Y D + A D GYRH D+A+ Y E+ + Sbjct: 19 IKLNNGQEIPQVALGVYKA--------PNDGSTENACKWAFDAGYRHIDSAARYMNEESV 70 Query: 253 GK 258 G+ Sbjct: 71 GR 72 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 66.9 bits (156), Expect = 6e-10 Identities = 27/58 (46%), Positives = 39/58 (67%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 E ++ I EG+V R+DIF+ +KLWN H V A+ +L +GLDY+DLY +H+PI Sbjct: 57 EGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPI 114 Score = 58.8 bits (136), Expect = 1e-07 Identities = 27/65 (41%), Positives = 40/65 (61%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G++K IG+SNF ++ +L+ IKP A+QIE H Q+ +VEFC+ + V+ Sbjct: 158 CVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVA 217 Query: 674 YSPFG 688 YS FG Sbjct: 218 YSSFG 222 Score = 37.5 bits (83), Expect = 0.39 Identities = 22/60 (36%), Positives = 31/60 (51%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG MP +GLG + K K + + AI +GYR FD A Y E+E+G+ Sbjct: 7 LNNGLKMPLVGLGCW---------KIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGE 57 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 66.5 bits (155), Expect = 7e-10 Identities = 29/56 (51%), Positives = 40/56 (71%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 +K +EGVV+R+D+FIT+KLWNT H E + SL L +DY+DLYL+HWP+ Sbjct: 61 LKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPV 114 Score = 63.3 bits (147), Expect = 7e-09 Identities = 31/62 (50%), Positives = 41/62 (66%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+ K IG+SNF K E++L I P AIQIE+H QKE+VEF +S+G+ V+ YS Sbjct: 152 GLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSL 211 Query: 686 GS 691 GS Sbjct: 212 GS 213 Score = 50.0 bits (114), Expect = 7e-05 Identities = 24/60 (40%), Positives = 36/60 (60%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 K+NNG+++P +GLGT+ G + V L + A+ +GYRH DTA +Y E+ IG Sbjct: 7 KLNNGKEIPTVGLGTW-GMEDEAV-------LEGAIRNALSLGYRHIDTAFIYGNEKMIG 58 >UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 234 Score = 66.5 bits (155), Expect = 7e-10 Identities = 31/63 (49%), Positives = 42/63 (66%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440 +K KI VK DI++TTK+WN + + V ++NDSLKKL LDY+ L+L+HWPI Sbjct: 97 LKRKINN--VKGPDIWVTTKVWNHLYDKDGVQWSLNDSLKKLNLDYVGLFLIHWPISCEK 154 Query: 441 DYS 449 YS Sbjct: 155 AYS 157 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 66.1 bits (154), Expect = 1e-09 Identities = 29/89 (32%), Positives = 53/89 (59%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + V + I+E + R+D+F+T+K+WN Q +A ++++ L LDY+DLYL+HWP Sbjct: 54 KGVGLGIKEANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAA 113 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + + ++ +TW +E + G +KA Sbjct: 114 HQFENWKQLN-NDTWSAMEKLYKDGKIKA 141 Score = 56.8 bits (131), Expect = 6e-07 Identities = 25/62 (40%), Positives = 38/62 (61%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G +K +G+SNF + L +L+ TIKP QIE H +Q++ V+FC + V G+SP Sbjct: 136 DGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCNDNNIQVEGWSP 195 Query: 683 FG 688 G Sbjct: 196 LG 197 Score = 43.6 bits (98), Expect = 0.006 Identities = 21/60 (35%), Positives = 34/60 (56%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 K+NN ++PAIG GT+ D + + + AID GY+H D A++Y+ E+ +G Sbjct: 6 KLNNNINIPAIGFGTWQTPDGQTAINA--------IKTAIDAGYKHIDAAAIYKNEKGVG 57 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 65.7 bits (153), Expect = 1e-09 Identities = 34/89 (38%), Positives = 50/89 (56%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EAV + E R +IF+TTK H R V +A+ SL++LGLDY+DL+LMHWP+ Sbjct: 59 EAVGKAVREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMPG 118 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 Y ++ +RG+ + + G KA Sbjct: 119 EGSY-------VDAYRGMVELKEQGLAKA 140 Score = 42.7 bits (96), Expect = 0.010 Identities = 23/68 (33%), Positives = 36/68 (52%) Frame = +1 Query: 55 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 T P+++++ G MP +G+GT+ K ++ R V AI+ GYR DTA Y Sbjct: 5 TTPTPTVELSGGTRMPMLGMGTW---------PLKGEECRAAVASAIEQGYRLVDTAEAY 55 Query: 235 ETEQEIGK 258 E+ +GK Sbjct: 56 GNEEAVGK 63 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 65.7 bits (153), Expect = 1e-09 Identities = 35/91 (38%), Positives = 53/91 (58%), Gaps = 3/91 (3%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---I 428 A+ + E + RED F+T+KLW T+ +A + +L++LG DY+DLYL+HWP + Sbjct: 56 ALGQAVAESDIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDL 115 Query: 429 GLNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 L D++ D ETWR LE G ++A Sbjct: 116 ELE-DWAKLD---RETWRALERLYESGLVRA 142 Score = 54.0 bits (124), Expect = 4e-06 Identities = 25/66 (37%), Positives = 36/66 (54%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 670 R +G+V+ IG+SNF LE +L + P Q+E H Q E V FCQ+ ++V Sbjct: 133 RLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHPGYTQDEAVAFCQNHSILVE 192 Query: 671 GYSPFG 688 +SP G Sbjct: 193 AWSPLG 198 Score = 45.6 bits (103), Expect = 0.001 Identities = 26/60 (43%), Positives = 33/60 (55%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 ++NG +PA+G GTY D + V S AI GYRHFDTAS Y TE +G+ Sbjct: 10 LSNGLSIPAVGFGTYKTGDGDSAVLSN----------AIAQGYRHFDTASFYGTETALGQ 59 >UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 419 Score = 65.3 bits (152), Expect = 2e-09 Identities = 30/74 (40%), Positives = 46/74 (62%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 I+E VKRE+++ITTKLW T + Q+ +S +LG++Y+DL+L+HWP S Sbjct: 69 IQESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLIHWPDAQLPGKSS 128 Query: 453 SDVDFMETWRGLED 494 + ETWR +E+ Sbjct: 129 REAR-AETWRAMEE 141 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 65.3 bits (152), Expect = 2e-09 Identities = 27/57 (47%), Positives = 40/57 (70%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 ++K +EG +KREDIF T+KLWN+ H V + +++ LG+ Y+DLYL+HWPI Sbjct: 71 SLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPI 127 Score = 54.0 bits (124), Expect = 4e-06 Identities = 25/61 (40%), Positives = 36/61 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+VK IG+SNFN Q L +L IKP Q+E+H Q ++ E+C + ++ YSP Sbjct: 170 GLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPL 229 Query: 686 G 688 G Sbjct: 230 G 230 Score = 44.0 bits (99), Expect = 0.005 Identities = 23/62 (37%), Positives = 36/62 (58%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 + K+N+G +P+IGLGTY + +N ++ D + A+ GYRH D A+ Y E+ Sbjct: 16 NFKLNDGNQIPSIGLGTY--YSEN------PGEVGDAINNALKNGYRHIDGAAFYGNEKV 67 Query: 250 IG 255 IG Sbjct: 68 IG 69 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 65.3 bits (152), Expect = 2e-09 Identities = 28/46 (60%), Positives = 36/46 (78%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 +KRE+I+IT+KLWNT HR V +A +LK L LDY+DLYLMH+P Sbjct: 60 IKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYP 105 Score = 46.4 bits (105), Expect = 8e-04 Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERV-LKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+VK IG+SN+ QLER+ + P Q+E +L Q + E+ EG++V GYS Sbjct: 148 GLVKRIGVSNWTINQLERLKYSDAKTTPYTNQVEFNLYMQQGPLREYMHKEGIIVTGYST 207 Query: 683 FGS 691 G+ Sbjct: 208 LGT 210 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 64.9 bits (151), Expect = 2e-09 Identities = 32/78 (41%), Positives = 44/78 (56%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 +KR++ F+TTK+WNT+ E +A S KKL LD +DLYL+HWP F Sbjct: 69 LKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---------KQDTF 119 Query: 468 METWRGLEDAQRMG*LKA 521 ETWR +E G ++A Sbjct: 120 FETWRAVEKLYDEGLVRA 137 Score = 48.8 bits (111), Expect = 2e-04 Identities = 25/60 (41%), Positives = 36/60 (60%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 ++NNG +MP G G Y D+ +++R + A+DVGYR FDTAS Y E+E+G Sbjct: 10 RLNNGIEMPRHGFGVYKLTDE--------QRMRTALETAVDVGYRLFDTASFYHNEKELG 61 Score = 37.1 bits (82), Expect = 0.52 Identities = 17/61 (27%), Positives = 30/61 (49%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+V+ IG+SNF L+R+ + P Q+E H + + + + +V +SP Sbjct: 133 GLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVHQAWSPL 192 Query: 686 G 688 G Sbjct: 193 G 193 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 64.9 bits (151), Expect = 2e-09 Identities = 37/89 (41%), Positives = 50/89 (56%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +AV I+ V REDIFIT+K+W + +A +DS+KKL LDYIDLYL+H P Sbjct: 54 QAVGDAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN- 112 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D+ TWR LE + G ++A Sbjct: 113 ---------DYYGTWRALERLYQEGRIRA 132 Score = 39.9 bits (89), Expect = 0.074 Identities = 23/59 (38%), Positives = 30/59 (50%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 +NNG MP +G G Y D Q + VV ++VGYR DTA +Y EQ +G Sbjct: 7 LNNGIKMPRLGFGVYQIDDL--------AQAQQVVEDGLEVGYRLVDTAQIYGNEQAVG 57 Score = 39.5 bits (88), Expect = 0.097 Identities = 19/73 (26%), Positives = 39/73 (53%) Frame = +2 Query: 467 HGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 646 +G + R G ++ IG+S+F ++L ++ +KP QIE ++ N + + ++ Sbjct: 115 YGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQYM 174 Query: 647 QSEGVVVMGYSPF 685 + EGV ++PF Sbjct: 175 EKEGVQPEAWAPF 187 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 64.9 bits (151), Expect = 2e-09 Identities = 36/88 (40%), Positives = 50/88 (56%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 AV I+ V R+DIF+TTKLW + + ++AI++ LK+LG DYID+ L+H G Sbjct: 57 AVGEAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG-- 114 Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D WR LEDAQ+ G K+ Sbjct: 115 --------DVAGAWRALEDAQKAGKTKS 134 Score = 40.3 bits (90), Expect = 0.056 Identities = 20/66 (30%), Positives = 35/66 (53%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++P +K+N+G ++P +G G + + + VK+ V AI GYR DTA Y Sbjct: 3 DIPKIKLNDGNEIPQLGFGVFQISNHDEAVKA--------VESAISNGYRLIDTAEAYNN 54 Query: 241 EQEIGK 258 + +G+ Sbjct: 55 QTAVGE 60 Score = 36.3 bits (80), Expect = 0.91 Identities = 21/60 (35%), Positives = 32/60 (53%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IG+SNF QL + +KP QIEV+ ++ V++ Q + V V ++PF Sbjct: 130 GKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNPWFQREPEVKWNQKDDVAVEAWAPF 189 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 64.9 bits (151), Expect = 2e-09 Identities = 29/56 (51%), Positives = 40/56 (71%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 AV ++ G V+RE++FITTKLWN + +A +S KKLG+DY+DLYL+HWP Sbjct: 64 AVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHWP 117 Score = 49.6 bits (113), Expect = 9e-05 Identities = 24/65 (36%), Positives = 38/65 (58%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 VP+L+MN+G+ P +GLG + + D+ V AI+ GYRH DTA++Y E Sbjct: 8 VPTLEMNDGKTTPQLGLGVW---------QLSDEDTYTSVRAAIETGYRHIDTAAIYGNE 58 Query: 244 QEIGK 258 + +G+ Sbjct: 59 EAVGR 63 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 64.9 bits (151), Expect = 2e-09 Identities = 34/89 (38%), Positives = 49/89 (55%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 E V + I+E V RE++FIT+K+WN A SL++L LDY+DLYL+HWP Sbjct: 58 EGVGIGIKESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP--- 114 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + +TWR LE + G ++A Sbjct: 115 ------GKDKYKDTWRALEKLYKDGKIRA 137 Score = 56.4 bits (130), Expect = 8e-07 Identities = 23/60 (38%), Positives = 40/60 (66%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G ++ IG+SNF LE +LK+ IKP Q+E H + QKE+ ++C+++G+ + +SP Sbjct: 132 DGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKAQGIQLEAWSP 191 Score = 39.5 bits (88), Expect = 0.097 Identities = 22/62 (35%), Positives = 35/62 (56%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++K++NG +MP GLG + + N +S V AI GYR DTA++Y+ E+ Sbjct: 8 TVKLHNGVEMPWFGLGVFKVENGNEATES--------VKAAIKNGYRSIDTAAIYKNEEG 59 Query: 250 IG 255 +G Sbjct: 60 VG 61 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 64.9 bits (151), Expect = 2e-09 Identities = 32/66 (48%), Positives = 40/66 (60%), Gaps = 2/66 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ--NVQKEMVEFCQSEGVVVMGYS 679 G+V +G+SNF LE +LK TI P QIE H Q K +VEFCQS+G++V GY Sbjct: 135 GLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGYG 194 Query: 680 PFGSLV 697 P LV Sbjct: 195 PLSPLV 200 Score = 59.3 bits (137), Expect = 1e-07 Identities = 31/85 (36%), Positives = 48/85 (56%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 E V + ++E V R +FIT+K+ H + +A+N+SL+KLG DY+DLYL+H PI Sbjct: 58 EEVGVALKEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPI-- 112 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG 509 + + E W+ +E A G Sbjct: 113 --PFYEKKIPISEGWKAMETALGTG 135 Score = 37.5 bits (83), Expect = 0.39 Identities = 19/53 (35%), Positives = 30/53 (56%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 +PA G+GT L + G + ++ + D V A+ G+ H D A VY E+E+G Sbjct: 12 VPAYGVGTALFKKEKGEI---NRTIVDSVKNALAAGFIHIDCAEVYGNEEEVG 61 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 64.5 bits (150), Expect = 3e-09 Identities = 32/88 (36%), Positives = 51/88 (57%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 +V I+ V R++IFIT+K+WN +A + LK L L+Y+DL L+HWPIG Sbjct: 64 SVSQGIKLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKG 123 Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + +V+ +TW+ +E+ G +KA Sbjct: 124 FKDNWQEVN-AQTWKAMEEFYLEGKIKA 150 Score = 55.2 bits (127), Expect = 2e-06 Identities = 26/60 (43%), Positives = 35/60 (58%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G +K IGLSNF +E + K I P Q+E H +Q E+VE+CQ +VV +SPF Sbjct: 146 GKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSPF 205 Score = 42.3 bits (95), Expect = 0.014 Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Frame = +1 Query: 52 STMEVPSLKMN---NGRDMPAIGLGTYLGFDQNGVVKSKD-KQLRDVVMRAIDVGYRHFD 219 +T ++ +K N N MP+IG GTY K +D KQ + V A++VGYRH D Sbjct: 4 TTKKIKVMKYNLLANNYKMPSIGFGTY---------KLEDGKQTVEAVKTALEVGYRHLD 54 Query: 220 TASVYETEQEIGK 258 A +YE + + + Sbjct: 55 CAEIYENQLSVSQ 67 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 64.5 bits (150), Expect = 3e-09 Identities = 27/57 (47%), Positives = 41/57 (71%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 443 I++ V R +IF+TTKLW T R + +A++ SL++LGLDY+ LYL+HWP+ L + Sbjct: 65 IQDSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRTE 119 Score = 50.8 bits (116), Expect = 4e-05 Identities = 24/64 (37%), Positives = 38/64 (59%), Gaps = 2/64 (3%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 676 +G K IG+SNF+ L+ +L T K P Q+E H Q+E++++C +G+V+ Y Sbjct: 158 SGKTKAIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAY 217 Query: 677 SPFG 688 SP G Sbjct: 218 SPLG 221 Score = 50.0 bits (114), Expect = 7e-05 Identities = 25/63 (39%), Positives = 38/63 (60%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 +LK+N G+ +P +GLGT+ +SK+ + V+ A+ GYRH D A+VY E E Sbjct: 10 TLKLNTGQTIPQVGLGTW---------RSKENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60 Query: 250 IGK 258 +GK Sbjct: 61 VGK 63 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 64.1 bits (149), Expect = 4e-09 Identities = 29/78 (37%), Positives = 45/78 (57%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 + RED+F+TTK+WN H +A + S+ LG++Y+DLYL+HWP F Sbjct: 83 LSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCARRG-------LF 135 Query: 468 METWRGLEDAQRMG*LKA 521 E++R +E R G ++A Sbjct: 136 TESYRAMETLYREGRIRA 153 Score = 41.5 bits (93), Expect = 0.024 Identities = 23/64 (35%), Positives = 32/64 (50%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 P L +NNG + +G G Y K +V A++ GYRHFDTA++Y E Sbjct: 5 PRLSLNNGVLIDQLGFGLY---------KVPPADAAGLVTMALEAGYRHFDTAAMYGNET 55 Query: 247 EIGK 258 +GK Sbjct: 56 GVGK 59 Score = 39.5 bits (88), Expect = 0.097 Identities = 20/61 (32%), Positives = 31/61 (50%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G ++ IG+SNF LE +L+ + P QIE+H Q E+ + G+ +SP Sbjct: 149 GRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSPL 208 Query: 686 G 688 G Sbjct: 209 G 209 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 64.1 bits (149), Expect = 4e-09 Identities = 28/60 (46%), Positives = 38/60 (63%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + V I+EG+VKRED+FI +KLWN+ H V L GLDY DL+++H+PI L Sbjct: 58 KGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIAL 117 Score = 54.0 bits (124), Expect = 4e-06 Identities = 25/62 (40%), Positives = 37/62 (59%) Frame = +2 Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 + + IG+SNF+ Q L +L+ I+P +QIE H Q+ +V + Q EG+ V YS FG Sbjct: 159 LARSIGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFG 218 Query: 689 SL 694 L Sbjct: 219 PL 220 Score = 44.8 bits (101), Expect = 0.003 Identities = 26/67 (38%), Positives = 33/67 (49%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M PS K+N+G DMP +G G + K ++ D + AI GYR FD A Y Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW---------KVNNETCADQIYHAIKAGYRLFDGACDYG 51 Query: 238 TEQEIGK 258 E E GK Sbjct: 52 NEVEAGK 58 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 64.1 bits (149), Expect = 4e-09 Identities = 30/60 (50%), Positives = 40/60 (66%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A+ KI +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P + Sbjct: 66 QAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125 Score = 48.8 bits (111), Expect = 2e-04 Identities = 25/63 (39%), Positives = 40/63 (63%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S+++N+G MP +G GTY + KS+ + V AIDVG+RH D+A +Y+ E+E Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63 Query: 250 IGK 258 +G+ Sbjct: 64 VGQ 66 Score = 33.1 bits (72), Expect = 8.5 Identities = 18/51 (35%), Positives = 31/51 (60%), Gaps = 3/51 (5%) Frame = +2 Query: 548 QLERVLKEGTI--KPDAIQI-EVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 691 +LE +L + + KP Q+ E H Q +++EFC+S+ +V++ YS GS Sbjct: 153 ELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGS 203 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 63.7 bits (148), Expect = 5e-09 Identities = 25/51 (49%), Positives = 35/51 (68%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 446 RED+F+TTKLWN+ +A + S+ KLGL+Y+DLYL+HWP+ Y Sbjct: 69 REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAKERY 119 Score = 46.0 bits (104), Expect = 0.001 Identities = 24/64 (37%), Positives = 35/64 (54%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A+G V+ IG+SNF + LER+ E ++ P QIE+H Q E +G+ +S Sbjct: 131 ADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQIELHPHLQQHAAREVHAEQGIATEAWS 190 Query: 680 PFGS 691 P GS Sbjct: 191 PLGS 194 Score = 41.5 bits (93), Expect = 0.024 Identities = 21/66 (31%), Positives = 35/66 (53%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 +VP + +NNG +MP +G G + + D + V A++ GYR DTA++Y Sbjct: 4 KVPPIILNNGVEMPQLGFGVW---------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54 Query: 241 EQEIGK 258 E+ G+ Sbjct: 55 EEGTGR 60 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 63.7 bits (148), Expect = 5e-09 Identities = 31/70 (44%), Positives = 42/70 (60%), Gaps = 2/70 (2%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHSDV 461 +KRED+FIT+K + +A SLKKL LDY+D YL+HWP GL+ S + + Sbjct: 86 IKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSI 145 Query: 462 DFMETWRGLE 491 +TWR LE Sbjct: 146 QRAQTWRALE 155 Score = 43.2 bits (97), Expect = 0.008 Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKEGT--IKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 676 V+ IG+SN+ L +L IKP Q+E H N QK+++EFC++ +++ Y Sbjct: 163 VRSIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQKDLLEFCKNNKIILESY 219 Score = 35.5 bits (78), Expect = 1.6 Identities = 18/54 (33%), Positives = 29/54 (53%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 MP +G+GT+ K + +++ ++ GYR DTAS+Y E+ IGK Sbjct: 27 MPMLGIGTF-----------KLNDIENIIKVGLENGYRRIDTASMYNNEERIGK 69 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 63.7 bits (148), Expect = 5e-09 Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 12/95 (12%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL------ 434 I G +KREDIF+T+KL T H +V + + LK L L+YIDLYL+H P Sbjct: 65 ISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGS 124 Query: 435 ------NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 N + + +++ ++TWR LE + G LKA Sbjct: 125 FAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKA 159 Score = 50.8 bits (116), Expect = 4e-05 Identities = 23/62 (37%), Positives = 36/62 (58%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G +K +G+SNF+ QL+ + +KP Q+E H+ Q+E+ C+ GV V Y+P Sbjct: 155 GKLKALGVSNFSCNQLQALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPL 214 Query: 686 GS 691 GS Sbjct: 215 GS 216 Score = 44.8 bits (101), Expect = 0.003 Identities = 27/68 (39%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRA-IDVGYRHFDTASVY 234 M V S+ +N G +P GLGT+ + KD+ V +RA +D GYR DTA +Y Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW---------QVKDEAELTVALRAALDAGYRLIDTAHLY 51 Query: 235 ETEQEIGK 258 + E IGK Sbjct: 52 QNEHIIGK 59 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 63.7 bits (148), Expect = 5e-09 Identities = 28/58 (48%), Positives = 39/58 (67%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 EA+ + EG VKRE++F+T+KLW H +V A +LK L LDY+DLYL+H P+ Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPV 117 Score = 60.5 bits (140), Expect = 5e-08 Identities = 25/64 (39%), Positives = 44/64 (68%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G+ K IG+SNF+ ++L ++L+ +I P Q+E+H Q+++ EFC S+G+++ YS Sbjct: 153 AKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFCDSKGILLTAYS 212 Query: 680 PFGS 691 P G+ Sbjct: 213 PLGN 216 Score = 45.2 bits (102), Expect = 0.002 Identities = 23/61 (37%), Positives = 36/61 (59%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 K+N G +PA+ LGT+ +S +++ + V AI++GYRH D A +Y E EIG Sbjct: 9 KLNTGASIPAMALGTW---------QSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIG 59 Query: 256 K 258 + Sbjct: 60 E 60 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 63.7 bits (148), Expect = 5e-09 Identities = 28/57 (49%), Positives = 38/57 (66%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 E V ++ V R+++FITTKLWN + QA+ SL+KL LDY+DLYL+HWP Sbjct: 55 EGVGKALKAAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP 109 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/68 (35%), Positives = 42/68 (61%) Frame = +1 Query: 55 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 TM+ P +K+ +GR MP +GLG + ++ ++ V +A++VGYR DTA++Y Sbjct: 2 TMQ-PLIKLYDGRLMPQLGLGVW---------QASIQETELAVSKALEVGYRSIDTAAIY 51 Query: 235 ETEQEIGK 258 + E+ +GK Sbjct: 52 KNEEGVGK 59 Score = 37.1 bits (82), Expect = 0.52 Identities = 17/59 (28%), Positives = 33/59 (55%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+++ IG+ NF+ L+R++ E I P QIE+H Q+++ + + + +SP Sbjct: 130 GLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNATHHIATESWSP 188 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 63.3 bits (147), Expect = 7e-09 Identities = 32/68 (47%), Positives = 42/68 (61%), Gaps = 6/68 (8%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTK------LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 416 EA++ KI+E VKRED+FI +K LW T R V +A +LK L L Y+D+YL+ Sbjct: 77 EAIQEKIQEQAVKREDLFIVSKVHMAHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLI 136 Query: 417 HWPIGLNA 440 HWP G A Sbjct: 137 HWPQGFKA 144 Score = 60.1 bits (139), Expect = 6e-08 Identities = 25/64 (39%), Positives = 43/64 (67%), Gaps = 2/64 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 G+VK +G+SNFN Q+E++L + +K P Q+E H Q++++++C S+G+ + YS Sbjct: 152 GLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYS 211 Query: 680 PFGS 691 P GS Sbjct: 212 PLGS 215 Score = 39.5 bits (88), Expect = 0.097 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = +1 Query: 151 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 KS ++++ V AID GYRH D A VY+ E E+G+ Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGE 77 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 63.3 bits (147), Expect = 7e-09 Identities = 31/89 (34%), Positives = 52/89 (58%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A+ ++ V+R+++FIT+KLWN + + N SL LGLDY+DL+L+HWP Sbjct: 54 KALGSALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP--- 110 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 +D ++E+++ LE G +KA Sbjct: 111 ----CENDQLYIESYKALEHLYEEGKIKA 135 Score = 52.4 bits (120), Expect = 1e-05 Identities = 27/59 (45%), Positives = 35/59 (59%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 +NNG MPA+GLG Y K D+Q+ +VV A+D GYR FDTA Y E+ +G Sbjct: 8 LNNGYPMPAVGLGVY---------KIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALG 57 Score = 46.8 bits (106), Expect = 6e-04 Identities = 21/59 (35%), Positives = 33/59 (55%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G +K IG+ NF LE+++KE I P QIE+H Q+++ +FC + V + P Sbjct: 131 GKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDFCDEHDIKVTAWMP 189 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 63.3 bits (147), Expect = 7e-09 Identities = 26/54 (48%), Positives = 40/54 (74%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 I+ V R ++F+TTK+W T HR+ E +++SL++LGLDY+DL L+HWP+ L Sbjct: 95 IKASGVPRSELFVTTKIWCTYHRQPEAC--LDESLQRLGLDYVDLLLVHWPVPL 146 Score = 54.0 bits (124), Expect = 4e-06 Identities = 25/64 (39%), Positives = 40/64 (62%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G K IG+SN++ L+++L + I P A Q+E+H Q E+V++C +G++ YS Sbjct: 182 ATGKTKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYS 241 Query: 680 PFGS 691 P GS Sbjct: 242 PLGS 245 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 63.3 bits (147), Expect = 7e-09 Identities = 34/99 (34%), Positives = 53/99 (53%), Gaps = 10/99 (10%) Frame = +3 Query: 255 EAVKMKIEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 EAV + G+V R D+F+T+KLW + V A ++L+ LG+DY+DL L+HWP Sbjct: 65 EAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPAT 124 Query: 432 L---NADYSHSD------VDFMETWRGLEDAQRMG*LKA 521 + + D+ D WRG+E+ R+G +A Sbjct: 125 VAPGSYDFPFPKEEMAPAFDMEGVWRGMEECHRLGLARA 163 Score = 58.4 bits (135), Expect = 2e-07 Identities = 27/73 (36%), Positives = 45/73 (61%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ + IG+SNF+ ++LE++L ++P A Q+E++ Q+ + E C+ EGV + G Sbjct: 155 CHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLCG 214 Query: 674 YSPFGSLVARHGS 712 YSP G+ GS Sbjct: 215 YSPLGAKGTPWGS 227 Score = 39.1 bits (87), Expect = 0.13 Identities = 20/49 (40%), Positives = 29/49 (59%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 MP IG+GT + ++ ++RAI++GYRHFDTA +Y TE Sbjct: 18 MPRIGMGTA------AFPFTSSEETTAALLRAIELGYRHFDTARLYATE 60 >UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Putative uncharacterized protein - Parvularcula bermudensis HTCC2503 Length = 278 Score = 62.9 bits (146), Expect = 9e-09 Identities = 22/52 (42%), Positives = 41/52 (78%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 I++ + R+++F+TTK+WN ++ ++A+++SL +LGLDY++L L+HWPI Sbjct: 57 IKDSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI 108 Score = 34.7 bits (76), Expect = 2.8 Identities = 16/45 (35%), Positives = 27/45 (60%) Frame = +1 Query: 124 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 LGF G + + + R AI+ GYRH D A++Y+ E+++G+ Sbjct: 14 LGF---GTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGE 55 Score = 34.3 bits (75), Expect = 3.7 Identities = 25/84 (29%), Positives = 37/84 (44%) Frame = +2 Query: 470 GDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQ 649 G LA I R +G K IG+SN+N+ Q + AIQ E H Q +++ + Sbjct: 118 GPLAEIKR---SGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPILKTAR 174 Query: 650 SEGVVVMGYSPFGSLVARHGSTVE 721 ++ YSP G A +E Sbjct: 175 GFDMMFTSYSPLGRGEAMSNPAIE 198 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 62.9 bits (146), Expect = 9e-09 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 9/94 (9%) Frame = +3 Query: 255 EAVKMKIEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 EA+ + G+V+ R + F+TTKLW V AI SLK L LDY+DLY++HWP+ Sbjct: 68 EALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVS 127 Query: 432 LNA--------DYSHSDVDFMETWRGLEDAQRMG 509 + +DF W +E+ QR+G Sbjct: 128 SKPGKYKFPIDEDDFMPMDFEVVWSEMEECQRLG 161 Score = 44.4 bits (100), Expect = 0.003 Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Frame = +1 Query: 52 STMEVPSLKMNNG----RDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFD 219 S VP+L + +G MP +G GT + L++ V+ AI +GYRHFD Sbjct: 2 SLTTVPTLAIRSGPSGHHSMPVLGFGTAAS------PLPEPTMLKETVIEAIKLGYRHFD 55 Query: 220 TASVYETEQEIGK 258 T+ Y+TE+ IG+ Sbjct: 56 TSPRYQTEEPIGE 68 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 62.9 bits (146), Expect = 9e-09 Identities = 35/103 (33%), Positives = 57/103 (55%), Gaps = 14/103 (13%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + V + I++ V R +IF+T+K+W++ H R E + ++ +LK L DY+DLYL+HWP+ L Sbjct: 87 DEVGLGIKDSGVPRSEIFLTSKVWSSYHDRVE--ECLDTTLKSLQTDYLDLYLIHWPVRL 144 Query: 435 NADYSHS--------------DVDFMETWRGLEDAQRMG*LKA 521 + +H D D +TW +ED + G KA Sbjct: 145 APNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKA 187 Score = 52.0 bits (119), Expect = 2e-05 Identities = 22/62 (35%), Positives = 37/62 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IGLSN +E ++K G + P Q+E+H Q ++++C+ +G+++ YSP Sbjct: 183 GKAKAIGLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPL 242 Query: 686 GS 691 GS Sbjct: 243 GS 244 Score = 49.6 bits (113), Expect = 9e-05 Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = +1 Query: 58 MEVP-SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 M P S K+N G +PAIGLGT+ ++K ++R V A+ GYRH D A Y Sbjct: 33 MSAPTSFKLNTGASIPAIGLGTW---------QAKAGEVRQAVAHALKAGYRHIDGALCY 83 Query: 235 ETEQEIG 255 + E E+G Sbjct: 84 QNEDEVG 90 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 62.5 bits (145), Expect = 1e-08 Identities = 25/56 (44%), Positives = 39/56 (69%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 V I E + R++IFITTKLWN + +A+ +SL +LG+D++DLYL+H+P+ Sbjct: 63 VGQAIRESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPV 118 Score = 50.0 bits (114), Expect = 7e-05 Identities = 23/64 (35%), Positives = 40/64 (62%), Gaps = 1/64 (1%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQ 246 ++ +NNG MP +GLG + K+K K+ ++ V+ A++ GYRH DTA +Y+ E Sbjct: 11 TIMLNNGISMPILGLGVW---------KTKSGKECKEAVLNALEAGYRHIDTARIYDNEV 61 Query: 247 EIGK 258 ++G+ Sbjct: 62 DVGQ 65 Score = 42.7 bits (96), Expect = 0.010 Identities = 23/73 (31%), Positives = 35/73 (47%) Frame = +2 Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 + K IG+SN+ L +LK I P Q+E H Q ++E+C+ + + YSP Sbjct: 137 LCKAIGVSNYTIIHLTELLKNSQITPAVNQVEFHPFLNQIHLLEYCKKHKIQLEAYSPLA 196 Query: 689 SLVARHGSTVEGP 727 HG +E P Sbjct: 197 -----HGQKIEDP 204 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 62.5 bits (145), Expect = 1e-08 Identities = 34/87 (39%), Positives = 48/87 (55%), Gaps = 12/87 (13%) Frame = +3 Query: 285 VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-------- 440 V R ++F+TTKL V A+ +SL +LGLDY+DL+L+HWP+ + Sbjct: 87 VASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAIGKKDAAGELT 146 Query: 441 --DYSHSDVDF-ME-TWRGLEDAQRMG 509 D S V F ME WRG+E+ R+G Sbjct: 147 WDDLSRGLVPFDMEGVWRGMEECHRLG 173 Score = 53.2 bits (122), Expect = 7e-06 Identities = 26/73 (35%), Positives = 42/73 (57%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+ + IG+SNF+ ++ R+L + P Q+E+++ Q+++ E C GVVV Sbjct: 169 CHRLGLARSIGVSNFSAAKMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAA 228 Query: 674 YSPFGSLVARHGS 712 YSP G+ A GS Sbjct: 229 YSPLGAHGAHWGS 241 Score = 44.8 bits (101), Expect = 0.003 Identities = 24/69 (34%), Positives = 35/69 (50%) Frame = +1 Query: 49 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228 A+ VP + +N+G MP +G GT + L + A+ +GYRH DTA+ Sbjct: 15 AAATAVPCVTLNSGHAMPVLGFGTGSS--------TPPADLAATIAHAVRLGYRHLDTAA 66 Query: 229 VYETEQEIG 255 VY TE +G Sbjct: 67 VYGTEGAVG 75 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 62.5 bits (145), Expect = 1e-08 Identities = 35/99 (35%), Positives = 55/99 (55%), Gaps = 10/99 (10%) Frame = +3 Query: 255 EAVKMKIEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLK---------KLGLDYID 404 EA+K ++ G++K R+++FIT+KLW + V A+ ++LK L LDY+D Sbjct: 63 EAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLD 122 Query: 405 LYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 LYL+HW G H +D W+ +ED Q++ KA Sbjct: 123 LYLIHWSDG------HLPIDLGSVWKAMEDFQKLSLTKA 155 Score = 35.1 bits (77), Expect = 2.1 Identities = 17/68 (25%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = +1 Query: 58 MEVPSLKMNN-GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 + +P + + + G+ +P +G+ T + + + + D ++ AI++GYRHFD + Y Sbjct: 2 ISIPEMTLGSTGKAIPLVGMVTTV------YPFAPSETMIDSILTAIELGYRHFDCVAAY 55 Query: 235 ETEQEIGK 258 +E+ +G+ Sbjct: 56 LSEKPLGE 63 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 62.5 bits (145), Expect = 1e-08 Identities = 27/61 (44%), Positives = 43/61 (70%), Gaps = 4/61 (6%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----NADYSHS 455 VKRED++I +KLW H +VA I+++L+ L L+Y+D++LMHWP+ + + DY+ S Sbjct: 59 VKREDLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASS 118 Query: 456 D 458 D Sbjct: 119 D 119 Score = 38.3 bits (85), Expect = 0.23 Identities = 20/56 (35%), Positives = 25/56 (44%) Frame = +2 Query: 521 IGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 IG+SN L +L IKP Q E ++EFC S G+ V Y P G Sbjct: 150 IGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYVTAYRPLG 205 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 62.5 bits (145), Expect = 1e-08 Identities = 26/66 (39%), Positives = 42/66 (63%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 670 +C G+ + IG+SNFN+ Q+ +L + +I P QIE + Q+ M +FCQ + ++VM Sbjct: 152 QCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILVM 211 Query: 671 GYSPFG 688 GY+P G Sbjct: 212 GYTPLG 217 Score = 58.0 bits (134), Expect = 3e-07 Identities = 27/64 (42%), Positives = 42/64 (65%), Gaps = 1/64 (1%) Frame = +3 Query: 255 EAVKMKIEE-GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 EA++ KI E + R+D FI +KL + HR+ V + +L +LG+DY+DLYLMH P+ Sbjct: 61 EAIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVA 120 Query: 432 LNAD 443 L ++ Sbjct: 121 LQSE 124 Score = 39.1 bits (87), Expect = 0.13 Identities = 22/54 (40%), Positives = 29/54 (53%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +P IGLGTY +G ++ + AIDVGYR FDTA Y E +G+ Sbjct: 17 LPTIGLGTYSILGADG---------KEAIRTAIDVGYRMFDTAVAYGNEAIVGE 61 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 62.1 bits (144), Expect = 2e-08 Identities = 34/78 (43%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = +3 Query: 291 KREDIFITTKLWN-TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 KR+ IF+TTK++N Q ++ QA+N+ LKKL +Y+DL L+HWP+ N Y+ Sbjct: 77 KRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPV--NDKYN------ 128 Query: 468 METWRGLEDAQRMG*LKA 521 E+WR LED + G KA Sbjct: 129 -ESWRALEDIYKDGQAKA 145 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/63 (33%), Positives = 36/63 (57%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G K IG+ NFN +++ +L IKP QIE + Q ++V+FC+ + + +SP Sbjct: 140 DGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKFCRENDIQLEAWSP 199 Query: 683 FGS 691 G+ Sbjct: 200 LGN 202 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 62.1 bits (144), Expect = 2e-08 Identities = 29/75 (38%), Positives = 44/75 (58%) Frame = +2 Query: 464 LHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 643 + G + C G+ K IG+SNF+ ++LE +L TI P A Q+EVH Q ++ EF Sbjct: 142 MEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATISPAANQVEVHPYCRQNKLREF 201 Query: 644 CQSEGVVVMGYSPFG 688 C+ +G+ + YSP G Sbjct: 202 CKEKGIQLCAYSPLG 216 Score = 59.7 bits (138), Expect = 9e-08 Identities = 31/100 (31%), Positives = 58/100 (58%), Gaps = 11/100 (11%) Frame = +3 Query: 255 EAVKMKIEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 +AV + G+V R++++IT+KLW V ++ +L+K+ ++Y+DLYL+H+P+ Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120 Query: 432 L-------NADYSHSDVDFME---TWRGLEDAQRMG*LKA 521 + + YS D+ M+ W+ +E+ QR+G KA Sbjct: 121 MRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKA 160 Score = 58.0 bits (134), Expect = 3e-07 Identities = 28/64 (43%), Positives = 42/64 (65%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +P +++G+ MP +G+GT F S ++DVV+RAI+ GYRHFDTA+VY+TE Sbjct: 1 MPEAALSSGKPMPRVGMGT-ASFPLGATDPST---VKDVVLRAIEAGYRHFDTAAVYQTE 56 Query: 244 QEIG 255 +G Sbjct: 57 AILG 60 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 61.7 bits (143), Expect = 2e-08 Identities = 25/61 (40%), Positives = 41/61 (67%) Frame = +2 Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 + + IGLSNFN +Q+ER+L+ TI+P QI+ H Q ++ ++C + G+ V+ YSP G Sbjct: 138 LTRAIGLSNFNSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSPLG 197 Query: 689 S 691 + Sbjct: 198 A 198 Score = 60.1 bits (139), Expect = 6e-08 Identities = 27/61 (44%), Positives = 36/61 (59%) Frame = +2 Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 + K IG+SNFN Q++R+LK I P QIE H Q ++ +FC G+ V YSP G Sbjct: 330 LTKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLG 389 Query: 689 S 691 S Sbjct: 390 S 390 Score = 46.8 bits (106), Expect = 6e-04 Identities = 25/54 (46%), Positives = 33/54 (61%), Gaps = 12/54 (22%) Frame = +3 Query: 366 NDSLKKLGLDYIDLYLMHWPIGLNADYS-H-----------SDVDFMETWRGLE 491 ++SLK L LDY+D+YLMHWP L S H SDVDF++TW+ +E Sbjct: 270 SESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAME 323 Score = 45.2 bits (102), Expect = 0.002 Identities = 27/78 (34%), Positives = 43/78 (55%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 A++ IE G ++R+D+F+ +K T V A+ D+LKKL + Y+DLYL+ P Sbjct: 61 ALQQLIEGGKIRRKDLFLMSKFCCTNTTNL-VKAALLDTLKKLQVAYLDLYLIERPPAC- 118 Query: 438 ADYSHSDVDFMETWRGLE 491 D + +ETW +E Sbjct: 119 -----KDHNLIETWEAME 131 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 61.7 bits (143), Expect = 2e-08 Identities = 35/89 (39%), Positives = 49/89 (55%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 E V I++ +KREDIFITTK+W + + +I+ SLKKL +YIDL L+H P G Sbjct: 53 EFVGNAIKQTKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG- 111 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D+ W+ LE + G +KA Sbjct: 112 ---------DYYSAWKALEVLYKKGIVKA 131 Score = 41.9 bits (94), Expect = 0.018 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAID-VGYRHFDTASVYETEQE 249 +K+ NG MP IGLG Y K++ + + +++AID GYR DTA VY E+ Sbjct: 4 IKLANGLHMPIIGLGVY---------KAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEF 54 Query: 250 IG 255 +G Sbjct: 55 VG 56 Score = 38.3 bits (85), Expect = 0.23 Identities = 22/61 (36%), Positives = 31/61 (50%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 GIVK IG+SNF +L +KP QIE+H + E + + GV V ++ F Sbjct: 127 GIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPLRQRIEDLHWNNKYGVAVESWASF 186 Query: 686 G 688 G Sbjct: 187 G 187 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 61.7 bits (143), Expect = 2e-08 Identities = 35/101 (34%), Positives = 54/101 (53%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + V I++ + R+ I++T+KLW + ++AI+ SL KL LDYIDLYL+H P G Sbjct: 56 DEVGQAIKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQPYG- 114 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKASDCLTSTSSSWR 557 D W+ +E AQ+ G LK+ T + W+ Sbjct: 115 ---------DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQ 146 Score = 47.6 bits (108), Expect = 4e-04 Identities = 24/66 (36%), Positives = 37/66 (56%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 + P++ +N+GR +PAIG GT+ D ++ V A+ +GYRH DTA Y Sbjct: 3 KTPTITLNDGRAIPAIGFGTFQIPDDGSTYQA--------VKEALVIGYRHIDTAVAYFN 54 Query: 241 EQEIGK 258 E E+G+ Sbjct: 55 EDEVGQ 60 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 61.7 bits (143), Expect = 2e-08 Identities = 29/59 (49%), Positives = 37/59 (62%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 + V I VV RE++F+TTKLW ++ AI+DSLKKLG DY DL L+H P G Sbjct: 56 QGVNEAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG 114 Score = 39.1 bits (87), Expect = 0.13 Identities = 21/60 (35%), Positives = 31/60 (51%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG MP +G G + + ++ + V+ AI+ GYR DTA VY E E G+ Sbjct: 6 LNNGAQMPQLGFGVF---------QIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQ 56 >UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase related protein - Thermoplasma acidophilum Length = 284 Score = 61.7 bits (143), Expect = 2e-08 Identities = 24/45 (53%), Positives = 33/45 (73%) Frame = +3 Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 +RED+FI TK+W T +V ++ +SLKKLG DY+DLY +HWP Sbjct: 68 RREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP 112 Score = 33.9 bits (74), Expect = 4.8 Identities = 16/63 (25%), Positives = 37/63 (58%), Gaps = 4/63 (6%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERV---LKEGTIKPDAIQIEVHLQNVQKEMV-EFCQSEGVVVMG 673 G ++ IG+SNF+ ++++ L + I + ++ V + ++ E + +FC+ G+ ++ Sbjct: 132 GRIRYIGISNFSVKEMKEAMSALAKYRIVSNQLEYNVATREIEDEGIYDFCRKNGMAIIA 191 Query: 674 YSP 682 YSP Sbjct: 192 YSP 194 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 61.7 bits (143), Expect = 2e-08 Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 2/68 (2%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVV 667 C G+VK +G+SNFN++QLE +L + +K P + Q+E H Q ++++FCQ +V+ Sbjct: 157 CKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI 216 Query: 668 MGYSPFGS 691 YSP G+ Sbjct: 217 TAYSPLGT 224 Score = 58.0 bits (134), Expect = 3e-07 Identities = 27/58 (46%), Positives = 37/58 (63%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 EA++ KI EG V+REDIF KLW T H V + +L+ L LDY+DLY++ P+ Sbjct: 66 EAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123 Score = 43.6 bits (98), Expect = 0.006 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 249 + +++G +P IGLGTY KS K V AID GYRH D A +Y+ E E Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63 Query: 250 IGK 258 +G+ Sbjct: 64 VGE 66 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 61.3 bits (142), Expect = 3e-08 Identities = 27/66 (40%), Positives = 39/66 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IGLSNFN+ Q+ + IKP +Q+E H QK++ +FC+ +V+ Y+P Sbjct: 173 GRAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPL 232 Query: 686 GSLVAR 703 GS AR Sbjct: 233 GSHNAR 238 Score = 53.6 bits (123), Expect = 6e-06 Identities = 25/48 (52%), Positives = 33/48 (68%) Frame = +3 Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 KREDIFIT+KL + +R V + SLK LGLDY+D+YL+H P + Sbjct: 89 KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAV 136 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/65 (36%), Positives = 38/65 (58%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 V LK+++G ++PA+GLGT +K + + + + A++ GYRH DTA Y+ E Sbjct: 23 VEKLKLSSGHEIPAVGLGT-------STIKLDE--MDNAISSALENGYRHIDTAFSYDNE 73 Query: 244 QEIGK 258 IGK Sbjct: 74 AAIGK 78 >UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 274 Score = 61.3 bits (142), Expect = 3e-08 Identities = 22/45 (48%), Positives = 36/45 (80%) Frame = +3 Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 +RED+FI +K+W T RR ++ +++ ++LK+L DY+DLYL+HWP Sbjct: 75 RREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP 119 Score = 43.6 bits (98), Expect = 0.006 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 5/62 (8%) Frame = +1 Query: 88 GRDMPAIGLGTYL--GFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY---ETEQEI 252 G ++PA+GLGT+ GF+ S+D+++ +++ AI +GY H DTA Y TE+ I Sbjct: 10 GEEIPALGLGTWGIGGFETPDY--SRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELI 67 Query: 253 GK 258 GK Sbjct: 68 GK 69 Score = 42.7 bits (96), Expect = 0.010 Identities = 19/62 (30%), Positives = 40/62 (64%), Gaps = 3/62 (4%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGT--IKPDAIQIEVHLQNVQKE-MVEFCQSEGVVVMGY 676 G+++ IG+SNF+++ LE + + I D ++ + ++ +++ ++EFCQ GV ++ Y Sbjct: 139 GLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVKYNIEDRDPERDGLLEFCQKNGVTLVAY 198 Query: 677 SP 682 SP Sbjct: 199 SP 200 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 61.3 bits (142), Expect = 3e-08 Identities = 24/48 (50%), Positives = 36/48 (75%) Frame = +3 Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 G +KRED+F+T+KL+ T + ++ ++ SLK LG+ Y+DLYLMHWP Sbjct: 72 GSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWP 119 Score = 59.3 bits (137), Expect = 1e-07 Identities = 31/92 (33%), Positives = 49/92 (53%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+V+ IG+SNF QQ++ +LK I P Q+++H Q E+V+FCQS+G+ V ++P Sbjct: 159 GLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDELVKFCQSKGIHVSAHTPL 218 Query: 686 GSLVARHGSTVEGPRSTIQCSAPSPRIREDHS 781 G + G + G + P R S Sbjct: 219 GVPASGPGPSDSGSGGEDEPGTPRISFRRSRS 250 Score = 34.3 bits (75), Expect = 3.7 Identities = 21/60 (35%), Positives = 30/60 (50%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +N +PAIGLGT+ +S + V RA+ GYR D A +Y E E+G+ Sbjct: 14 LNTKAKIPAIGLGTW---------QSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGE 64 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 61.3 bits (142), Expect = 3e-08 Identities = 28/60 (46%), Positives = 41/60 (68%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + ++ I EG VKRE++FITTKL +R +VA+ + SL L L Y+DLYL+H+P G+ Sbjct: 72 QVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPCGI 131 Score = 57.6 bits (133), Expect = 3e-07 Identities = 25/63 (39%), Positives = 37/63 (58%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G K IGLSNFN Q++R++K ++P +Q+EVH+ Q + FC +VV + Sbjct: 164 AAGKTKNIGLSNFNADQVQRIIKGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFC 223 Query: 680 PFG 688 P G Sbjct: 224 PLG 226 Score = 49.6 bits (113), Expect = 9e-05 Identities = 24/66 (36%), Positives = 42/66 (63%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++P++ +N+G +P +GLGT +NG K ++ + V+ A++ GYRHFD+A+ Y Sbjct: 10 KIPTILLNSGSHIPVMGLGTG-SLGRNG--KMSEEAVTAVLETALECGYRHFDSAAYYGN 66 Query: 241 EQEIGK 258 E IG+ Sbjct: 67 EAIIGQ 72 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 61.3 bits (142), Expect = 3e-08 Identities = 27/74 (36%), Positives = 44/74 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G++K IG+SNFN L+ ++++ KP+ Q E+H K+ +EFCQ G++V YSP Sbjct: 152 GVIKHIGVSNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKTIEFCQKNGILVEAYSP- 210 Query: 686 GSLVARHGSTVEGP 727 L +H ++ P Sbjct: 211 --LARQHEKVMKHP 222 Score = 52.0 bits (119), Expect = 2e-05 Identities = 26/81 (32%), Positives = 49/81 (60%), Gaps = 4/81 (4%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA----DYSHS 455 +KRED+FIT+K+ + + +A+ D L +L + Y+D L+HWP G++ D ++ Sbjct: 77 IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP-GVSKLPPNDPKNA 135 Query: 456 DVDFMETWRGLEDAQRMG*LK 518 + +ETW+ L + ++ G +K Sbjct: 136 QIR-LETWKALIELRKAGVIK 155 Score = 46.0 bits (104), Expect = 0.001 Identities = 27/67 (40%), Positives = 34/67 (50%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 ++VP L G +P IG GTY QN + V A+ +GY H DTASVY Sbjct: 11 VKVPILNFREGGSIPQIGYGTY-ELRQNDCIIG--------VTEALKIGYTHIDTASVYR 61 Query: 238 TEQEIGK 258 EQ+I K Sbjct: 62 NEQDIAK 68 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 60.9 bits (141), Expect = 4e-08 Identities = 28/65 (43%), Positives = 43/65 (66%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +P++ +N+G +MPAIG GTY K +++ V AI+VGYRH DTAS+Y+ E Sbjct: 11 IPTITLNDGTEMPAIGFGTY---------KLREQDAYRAVRSAIEVGYRHIDTASLYKNE 61 Query: 244 QEIGK 258 +E+G+ Sbjct: 62 EEVGR 66 Score = 60.5 bits (140), Expect = 5e-08 Identities = 26/56 (46%), Positives = 36/56 (64%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 AV I G V R+++FITTK+WN H ++ +SL +LGLDYID ++HWP Sbjct: 67 AVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP 122 Score = 35.1 bits (77), Expect = 2.1 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 458 RGLHGD-LARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEM 634 +GL+ + A + + G ++ + ++NF + L ++ E I P Q+E+H Q E Sbjct: 126 KGLYVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVELHPGFSQAEQ 185 Query: 635 VEFCQSEGVVVMGYSPFG 688 + GVV +SP G Sbjct: 186 RAVDRELGVVTEAWSPLG 203 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 60.5 bits (140), Expect = 5e-08 Identities = 23/47 (48%), Positives = 34/47 (72%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 VKRED F+TTK+W + R ++ ++ +SL KL DY+DL L+HWP+ Sbjct: 63 VKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV 109 Score = 38.7 bits (86), Expect = 0.17 Identities = 20/57 (35%), Positives = 29/57 (50%) Frame = +1 Query: 85 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 NG D+P +G GT+ + +D+ V A+ GYRH DTA +Y E +G Sbjct: 8 NGADIPKLGFGTW---------QLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVG 55 Score = 33.1 bits (72), Expect = 8.5 Identities = 18/59 (30%), Positives = 28/59 (47%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G V+ IG+SNF L+ A Q+E H Q ++ C++ G+ + YSP Sbjct: 128 GQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAMTAYSP 186 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 60.1 bits (139), Expect = 6e-08 Identities = 26/58 (44%), Positives = 40/58 (68%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 +AV + + E V RE++F+TTKL + H ++ A+ SLK LGLD +DL+L+HWP+ Sbjct: 44 DAVGVALAECGVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPL 101 Score = 33.1 bits (72), Expect = 8.5 Identities = 19/65 (29%), Positives = 30/65 (46%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+V+ +G+SNF + L RV+ E P QI++ + + GV Sbjct: 117 CRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLPVRRADDELGVSTQS 176 Query: 674 YSPFG 688 +SP G Sbjct: 177 WSPLG 181 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 60.1 bits (139), Expect = 6e-08 Identities = 25/58 (43%), Positives = 35/58 (60%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 EA+ + +RED+F+T+KLW T V A +L L LDY+DLYL+HWP+ Sbjct: 74 EALAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPV 131 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 60.1 bits (139), Expect = 6e-08 Identities = 28/66 (42%), Positives = 41/66 (62%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 + P +K+NNG +MP +GLGT+L + GV + + AID GYRH DTA Y+ Sbjct: 4 KAPMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQN 54 Query: 241 EQEIGK 258 E+E+G+ Sbjct: 55 EKEVGE 60 Score = 57.2 bits (132), Expect = 5e-07 Identities = 26/61 (42%), Positives = 39/61 (63%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G VK IG+SNFN +Q+ R+L E IKP Q+E + Q+++ EFC++ + + YSP Sbjct: 120 GKVKSIGVSNFNSEQITRLLAECEIKPVTNQVECNPSLNQRKLTEFCKNLDITLTAYSPL 179 Query: 686 G 688 G Sbjct: 180 G 180 Score = 42.3 bits (95), Expect = 0.014 Identities = 24/54 (44%), Positives = 35/54 (64%), Gaps = 2/54 (3%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKL--WNTQHRRTEVAQAINDSLKKLGLDYIDLY 410 EA++ KIEEGVV RED+F+TTK W+T++ A + L+ +DYID + Sbjct: 60 EAIRAKIEEGVVCREDLFVTTKFIDWDTKNLMPYDA---DGKLQFSDVDYIDTW 110 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 60.1 bits (139), Expect = 6e-08 Identities = 28/65 (43%), Positives = 42/65 (64%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +PS +N G +P++G+G + G Q G +D +L D ++RAI VGYRH DTA+ Y E Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQG--QPG--PGRDNELVDALVRAIKVGYRHLDTATGYRNE 60 Query: 244 QEIGK 258 E+G+ Sbjct: 61 AEVGQ 65 Score = 54.0 bits (124), Expect = 4e-06 Identities = 26/61 (42%), Positives = 37/61 (60%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440 V + + V R +IF+TTKL +V Q + +SL +LG+DYIDL+L+HWP G Sbjct: 63 VGQAVRQSGVARSEIFVTTKL--RPGGVHDVVQELENSLNELGIDYIDLWLLHWPQGFTK 120 Query: 441 D 443 D Sbjct: 121 D 121 Score = 52.0 bits (119), Expect = 2e-05 Identities = 25/64 (39%), Positives = 37/64 (57%) Frame = +2 Query: 497 SANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 676 S G VK IG+SNF+ + LE + K + P QIE H + E+V++C+ + + V Y Sbjct: 157 SHKGKVKAIGVSNFSIKNLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAY 216 Query: 677 SPFG 688 SP G Sbjct: 217 SPLG 220 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 59.7 bits (138), Expect = 9e-08 Identities = 25/52 (48%), Positives = 36/52 (69%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 I+E V R+DI++T+KLW H V +A+ +LK L LDY+D YL+HWP+ Sbjct: 70 IKESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPV 121 Score = 57.6 bits (133), Expect = 3e-07 Identities = 30/62 (48%), Positives = 38/62 (61%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G V+ IGLSNFN LER+LK +KP Q+E+H Q E VE + G+ V YSPF Sbjct: 159 GKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPF 218 Query: 686 GS 691 G+ Sbjct: 219 GN 220 Score = 42.3 bits (95), Expect = 0.014 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = +1 Query: 85 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 +G +P +GLGT+ +S+ Q ++ V A+ GYRH D A++Y E E+G Sbjct: 20 DGSKIPGLGLGTW---------RSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVG 67 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 59.3 bits (137), Expect = 1e-07 Identities = 32/78 (41%), Positives = 43/78 (55%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 AV I+ + R D+FIT+K+WN + A + +L L LDY+DLYL+HWP N Sbjct: 53 AVGEAIKASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---N 109 Query: 438 ADYSHSDVDFMETWRGLE 491 D +D TWR LE Sbjct: 110 EDDFELTLD---TWRVLE 124 Score = 52.8 bits (121), Expect = 1e-05 Identities = 25/59 (42%), Positives = 37/59 (62%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 V+ IG+SNF++ QL++V + T+KP QIE H VQ ++ +F +V GYSP G Sbjct: 132 VRAIGVSNFSEDQLKQVFEMATVKPMINQIERHPYKVQADLGQFDTDNDIVNEGYSPIG 190 Score = 42.3 bits (95), Expect = 0.014 Identities = 22/61 (36%), Positives = 34/61 (55%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 +++NG +P +G GTYL + SKD + + A+D GYRH D A +Y E +G Sbjct: 5 QLSNGVTIPMLGFGTYL-------IDSKD--VPAAIKTALDAGYRHLDCAHIYGNEPAVG 55 Query: 256 K 258 + Sbjct: 56 E 56 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 59.3 bits (137), Expect = 1e-07 Identities = 28/84 (33%), Positives = 48/84 (57%) Frame = +3 Query: 267 MKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 446 + IE+ + RE+ FIT+K+WNT H +A + KKL ++Y+D+YL+H+ + Y Sbjct: 61 LAIEKSQIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFA----SSY 116 Query: 447 SHSDVDFMETWRGLEDAQRMG*LK 518 ++ETW +E+ G +K Sbjct: 117 ------YLETWHAMEELYLQGKIK 134 Score = 43.6 bits (98), Expect = 0.006 Identities = 22/61 (36%), Positives = 32/61 (52%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 +K NG +P +G G Y +K + V AI +GYRHFDTA +Y E+++ Sbjct: 8 IKAVNGIKIPQVGFGVYK--------LNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDL 59 Query: 253 G 255 G Sbjct: 60 G 60 Score = 41.9 bits (94), Expect = 0.018 Identities = 20/61 (32%), Positives = 33/61 (54%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G +K IG++NF Q LE ++K I P QIE H + Q E+ ++ ++ ++P Sbjct: 131 GKIKVIGVANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAPL 190 Query: 686 G 688 G Sbjct: 191 G 191 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 59.3 bits (137), Expect = 1e-07 Identities = 22/47 (46%), Positives = 34/47 (72%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 +KRED++IT+KLWN HR V + ++ L +DY+DL+L+HWP+ Sbjct: 61 IKREDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPL 107 Score = 50.0 bits (114), Expect = 7e-05 Identities = 26/65 (40%), Positives = 34/65 (52%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+VK IG+SN+ L +L IKP QIE+H + V+FC G+ V YSP Sbjct: 147 GLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIGVTAYSPM 206 Query: 686 GSLVA 700 G A Sbjct: 207 GGSYA 211 Score = 33.5 bits (73), Expect = 6.4 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = +1 Query: 124 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 LGF G ++ + ++ V A+ GYRH D A VY+ E+ IG+ Sbjct: 7 LGF---GTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGR 48 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 58.8 bits (136), Expect = 1e-07 Identities = 30/88 (34%), Positives = 49/88 (55%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 AV + + + R++IFIT+KL H + + I +SL ++ DY+DLYL+HWP Sbjct: 74 AVGAAVRQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWPNPQQ 133 Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521 Y +E W+ L DAQ+ G +++ Sbjct: 134 GLY-------IEAWQALIDAQKKGYIRS 154 Score = 44.4 bits (100), Expect = 0.003 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 4/114 (3%) Frame = +2 Query: 359 SYKRFTEETRSGLYRSLFDAL----AHWIKCRL*SFGRGLHGDLARIGRCSANGIVKGIG 526 +Y + E LYR FD L HW + G + A I G ++ IG Sbjct: 101 AYDKAMETIEESLYRMQFDYLDLYLIHWPNPQQ---GLYIEAWQALID-AQKKGYIRSIG 156 Query: 527 LSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 688 +SNF + +E + +E + P Q+E+H Q E + +S+ ++ M +SP G Sbjct: 157 VSNFLPKHIETLRRETGVIPVINQVELHPYFNQAEQRAYDESQQIITMAWSPLG 210 Score = 44.0 bits (99), Expect = 0.005 Identities = 24/64 (37%), Positives = 35/64 (54%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +P L +++G +PA+G GTY Q GV D ++RA+ GYR D+A YE E Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGV---------DTMLRALGHGYRMLDSAFNYENE 72 Query: 244 QEIG 255 +G Sbjct: 73 GAVG 76 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 58.8 bits (136), Expect = 1e-07 Identities = 24/59 (40%), Positives = 39/59 (66%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G V+ IG+SNF ++ +E ++ GTI P QIEVH+ V E++++C+ G+ + YSP Sbjct: 142 GKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVHIGKVPVELMDYCKKLGIKIEAYSP 200 Score = 51.6 bits (118), Expect = 2e-05 Identities = 29/77 (37%), Positives = 42/77 (54%), Gaps = 3/77 (3%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---IGLNADYSHSD 458 ++R DIF+TTKL +AI+ +L K GL+YIDL L+H P I +N Sbjct: 66 IERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTNDRHF 125 Query: 459 VDFMETWRGLEDAQRMG 509 +E WR +E+A + G Sbjct: 126 KGNLENWRAMEEAVKAG 142 Score = 44.0 bits (99), Expect = 0.005 Identities = 24/63 (38%), Positives = 36/63 (57%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S+ +NNG +P I LGT+L + ++ VV +A+++GYR FDTA Y E Sbjct: 6 SVILNNGEKIPQIQLGTWL---------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESG 56 Query: 250 IGK 258 +GK Sbjct: 57 VGK 59 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 58.8 bits (136), Expect = 1e-07 Identities = 23/58 (39%), Positives = 38/58 (65%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 E V I + R++++ITTK+WN+ +A+ +SL +L L+Y+DLYL+HWP+ Sbjct: 110 EGVGRAIRASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV 167 Score = 45.2 bits (102), Expect = 0.002 Identities = 22/68 (32%), Positives = 36/68 (52%) Frame = +2 Query: 485 IGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVV 664 + + A+G+ + IG+SNF L+R+ E I P Q+E+H + Q E+ F +V Sbjct: 180 LAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVELHPRLQQHELRAFHAKHRIV 239 Query: 665 VMGYSPFG 688 +SP G Sbjct: 240 TEAWSPLG 247 Score = 36.7 bits (81), Expect = 0.69 Identities = 19/65 (29%), Positives = 33/65 (50%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +P+L +++G +P +GLG + D V + A + GYR DTA +Y E Sbjct: 59 IPTLPLSDGTSIPQLGLGVWQMPDDGAGVP---------IQAAFNAGYRAIDTAPIYGNE 109 Query: 244 QEIGK 258 + +G+ Sbjct: 110 EGVGR 114 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 58.8 bits (136), Expect = 1e-07 Identities = 30/90 (33%), Positives = 54/90 (60%), Gaps = 1/90 (1%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 431 E++K +EG R+D+FI +K++ ++ + +++ SLK+L LDY+DLY +H+P+G Sbjct: 61 ESLKTIFKEGKYSRKDLFIVSKVF--PNKGINMLESVKKSLKELQLDYVDLYYLHFPLGF 118 Query: 432 LNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 L+ + W LE+A R+G K+ Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKS 148 Score = 53.6 bits (123), Expect = 6e-06 Identities = 28/63 (44%), Positives = 41/63 (65%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S K+NNG+ MP +GLGTYL + SK+ ++ +++ A+D GYRH DTA Y+ E Sbjct: 7 SSKLNNGQIMPLVGLGTYL-------LNSKE-EMTNLLRTALDAGYRHIDTAVNYQNEAM 58 Query: 250 IGK 258 IG+ Sbjct: 59 IGE 61 Score = 53.6 bits (123), Expect = 6e-06 Identities = 26/73 (35%), Positives = 41/73 (56%) Frame = +2 Query: 464 LHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 643 +H A++ G+ K IG+SNFN L +L +KP + Q+EV + QK +++F Sbjct: 130 VHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVSVFIQQKNLIKF 189 Query: 644 CQSEGVVVMGYSP 682 CQ G+ V Y+P Sbjct: 190 CQRFGIHVTAYAP 202 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 58.8 bits (136), Expect = 1e-07 Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 11/94 (11%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS- 449 I++ V RE+IF+ TKLW +V +A++DSL+ L Y+DL LMH+P Sbjct: 91 IKKSGVPREEIFLGTKLWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDR 150 Query: 450 ----------HSDVDFMETWRGLEDAQRMG*LKA 521 H + F++TWR LE + G ++A Sbjct: 151 FPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRA 184 Score = 52.0 bits (119), Expect = 2e-05 Identities = 29/86 (33%), Positives = 49/86 (56%), Gaps = 6/86 (6%) Frame = +2 Query: 455 GRGLHGDLARIGRCSA------NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 616 GR +HG+ + A G V+ IG+SNF+K ++E +L+E + P Q+EVH Sbjct: 157 GRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQMEVHPY 216 Query: 617 NVQKEMVEFCQSEGVVVMGYSPFGSL 694 QK E+ + +G+ V+ +SP G++ Sbjct: 217 LQQKGFNEWLREKGIHVVQFSPLGNM 242 Score = 35.5 bits (78), Expect = 1.6 Identities = 20/60 (33%), Positives = 32/60 (53%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +N G +PA+G+GT+ + D Q + V + + G R DTA VY EQ++G+ Sbjct: 40 LNTGAKIPALGVGTF---------QDPDSQ-EETVCQVLQRGMRLIDTARVYGVEQQVGR 89 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 58.8 bits (136), Expect = 1e-07 Identities = 24/51 (47%), Positives = 35/51 (68%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 I V R ++F+TTKL+N + +A ++SL +LGLDY+DLYL+HWP Sbjct: 62 IRNSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112 Score = 41.1 bits (92), Expect = 0.032 Identities = 19/65 (29%), Positives = 35/65 (53%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G + IG+ NF + QL+ ++ + P QIE+H QK ++ ++ G+V +SP Sbjct: 132 DGRARAIGVCNFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRALGIVTEAWSP 191 Query: 683 FGSLV 697 G + Sbjct: 192 IGGAI 196 Score = 39.9 bits (89), Expect = 0.074 Identities = 21/64 (32%), Positives = 32/64 (50%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 P + +NNG MPA+GLG + + ++ + AI GYR DTA Y E Sbjct: 6 PLINLNNGVKMPALGLGVFA---------ASAEETASAIASAISSGYRLIDTARSYNNEA 56 Query: 247 EIGK 258 ++G+ Sbjct: 57 QVGE 60 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 58.8 bits (136), Expect = 1e-07 Identities = 29/74 (39%), Positives = 44/74 (59%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 V R+++ + +K+ QH R E +I SL +LGLD IDL L+HWP + S + Sbjct: 66 VDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP-------NPSVGRW 118 Query: 468 METWRGLEDAQRMG 509 ++TWRG+ DA+ G Sbjct: 119 LDTWRGMIDAREAG 132 Score = 43.6 bits (98), Expect = 0.006 Identities = 25/65 (38%), Positives = 34/65 (52%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +P++ +N+GR GLGTY GV ++ AID GYR DTA YE E Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54 Query: 244 QEIGK 258 E+G+ Sbjct: 55 SEVGR 59 Score = 38.7 bits (86), Expect = 0.17 Identities = 18/59 (30%), Positives = 31/59 (52%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+V+ IG+SNF + L+ ++ E + P Q+E+H Q + F G+ +SP Sbjct: 132 GLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAFHDEHGIRTESWSP 190 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 58.4 bits (135), Expect = 2e-07 Identities = 28/62 (45%), Positives = 35/62 (56%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G V+ IGLSNFNK QL V + IKP +QIE+ N Q+ M E C + V +S Sbjct: 177 GRVRSIGLSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTL 236 Query: 686 GS 691 GS Sbjct: 237 GS 238 Score = 50.0 bits (114), Expect = 7e-05 Identities = 33/87 (37%), Positives = 45/87 (51%), Gaps = 14/87 (16%) Frame = +3 Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-----------GLN 437 KRED+FITTKL R V + SL+KLGL+Y+++YL+H P LN Sbjct: 91 KREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYEPALN 150 Query: 438 ADYS---HSDVDFMETWRGLEDAQRMG 509 D S +D D + WR +E + G Sbjct: 151 PDGSVVLDTDTDHVAIWRAMEKQVKAG 177 Score = 46.4 bits (105), Expect = 8e-04 Identities = 24/63 (38%), Positives = 36/63 (57%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++K+++G DMP IGLGT+ + + + V A++ GYRH DTA Y E+ Sbjct: 27 TIKLSSGHDMPMIGLGTW---------QMPPEAIEVAVTAALESGYRHIDTAFTYGNEEA 77 Query: 250 IGK 258 IGK Sbjct: 78 IGK 80 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 58.4 bits (135), Expect = 2e-07 Identities = 30/64 (46%), Positives = 42/64 (65%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 A+ I GVVKRED+FIT+K+WNT H +V + SLK +DY DL+L+ IG+ Sbjct: 59 AISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLVR-DIGV- 116 Query: 438 ADYS 449 ++YS Sbjct: 117 SNYS 120 Score = 34.7 bits (76), Expect = 2.8 Identities = 20/66 (30%), Positives = 30/66 (45%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M + + +G MP G GT+ K+ ++ V A+ GYRH D A+VY Sbjct: 1 MSTNTATLQSGAKMPLNGFGTW---------KASVEETEQAVTAALRAGYRHIDCAAVYW 51 Query: 238 TEQEIG 255 E +G Sbjct: 52 NEAAVG 57 Score = 33.9 bits (74), Expect = 4.8 Identities = 16/51 (31%), Positives = 27/51 (52%) Frame = +2 Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGV 661 +V+ IG+SN++ L L IKP Q E H+ + ++ + C+ GV Sbjct: 110 LVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCREFGV 160 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 58.0 bits (134), Expect = 3e-07 Identities = 34/83 (40%), Positives = 44/83 (53%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 +E + RED+FITTK+ N+ H A +I SL+ L DY+DL L+HWP L Y Sbjct: 73 LEASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP--LPTLYGG 130 Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521 D W LEDA G +A Sbjct: 131 ---DVALPWPALEDAFNAGGARA 150 Score = 48.8 bits (111), Expect = 2e-04 Identities = 24/64 (37%), Positives = 34/64 (53%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +P+ + G +P +G GTY K + D V RA++VGYRH DTA +Y E Sbjct: 16 IPTFMLPTGSPIPVLGFGTY---------KVAPEDTYDAVSRALEVGYRHIDTAQMYGNE 66 Query: 244 QEIG 255 E+G Sbjct: 67 AEVG 70 Score = 39.9 bits (89), Expect = 0.074 Identities = 18/59 (30%), Positives = 32/59 (54%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G + IGLSN+ ++ +E V + T+ P +Q+E H ++ + Q G+V +SP Sbjct: 146 GGARAIGLSNYEREHVEAVREVATVAPHVLQVESHPFFPNADLRAYAQGLGMVFEAWSP 204 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 58.0 bits (134), Expect = 3e-07 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IG 431 +A+ + + RED+ +TTK+W + +A + SLKKL LD++DLYL+HWP G Sbjct: 51 DAIGAALAAAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPATG 110 Query: 432 LN 437 +N Sbjct: 111 MN 112 Score = 39.5 bits (88), Expect = 0.097 Identities = 24/56 (42%), Positives = 29/56 (51%) Frame = +1 Query: 88 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 G +P +GLGT F G V RD V A+ +GYRH DTA +Y E IG Sbjct: 8 GVRLPKLGLGT---FRMQGTV------CRDAVESALALGYRHIDTAEMYANEDAIG 54 Score = 35.1 bits (77), Expect = 2.1 Identities = 27/130 (20%), Positives = 54/130 (41%), Gaps = 1/130 (0%) Frame = +2 Query: 338 PEN*SSPSYKRFTEETRSGLYRSLFDA-LAHWIKCRL*SFGRGLHGDLARIGRCSANGIV 514 PEN + + +R + + L D L HW + G L + + G Sbjct: 75 PENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP-----ATGMNLPAAMETLMALKQEGRT 129 Query: 515 KGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSL 694 + IG++NF L++ +++ Q+E H+ Q +++ + +S + ++ Y P Sbjct: 130 RAIGVANFTVALLKQAVEDIQAPVACNQVEYHVMLDQSKLMAYMKSRSIPLVAYCPLAQG 189 Query: 695 VARHGSTVEG 724 A T+ G Sbjct: 190 RAAGDETLAG 199 >UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 2,5-diketo-D-gluconic acid reductase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 159 Score = 58.0 bits (134), Expect = 3e-07 Identities = 22/44 (50%), Positives = 32/44 (72%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 R+++F+TTKLWN +A + SL+ LGLD++DLYL+HWP Sbjct: 68 RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111 Score = 39.5 bits (88), Expect = 0.097 Identities = 20/65 (30%), Positives = 34/65 (52%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 VP++ +NNG +MP +G G + + + + V A++ GYR DTA+ Y E Sbjct: 4 VPTVTLNNGVEMPQLGYGVF---------QVPEDETAAAVGAALEAGYRSIDTAAAYGNE 54 Query: 244 QEIGK 258 +G+ Sbjct: 55 AAVGR 59 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 58.0 bits (134), Expect = 3e-07 Identities = 28/66 (42%), Positives = 42/66 (63%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 + +K +E G+ R+D+F+T+K+W T V A+ ++LK L LDYIDLY +HWP L Sbjct: 68 KGLKAAMEAGI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRL 126 Query: 435 NADYSH 452 D +H Sbjct: 127 K-DGAH 131 Score = 50.4 bits (115), Expect = 5e-05 Identities = 23/63 (36%), Positives = 36/63 (57%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G+VK IG+ N+ +L R+L+ I P Q+E+H ++ E C+ G+ V YSP Sbjct: 157 DGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSP 216 Query: 683 FGS 691 GS Sbjct: 217 LGS 219 Score = 39.5 bits (88), Expect = 0.097 Identities = 21/60 (35%), Positives = 31/60 (51%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 + +G MPA+GLGT+ ++ V + GYRH DTA+ Y E+E+GK Sbjct: 18 LKSGHAMPAVGLGTW---------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGK 68 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 57.6 bits (133), Expect = 3e-07 Identities = 24/46 (52%), Positives = 32/46 (69%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 +KRE+ F+TTKLWN+ + +A SL L LDY+DLYL+HWP Sbjct: 71 IKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP 114 Score = 51.2 bits (117), Expect = 3e-05 Identities = 26/65 (40%), Positives = 38/65 (58%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 VPS+ + +G +P GLGTY + + VV AI++GYRH DTAS+Y E Sbjct: 9 VPSVLLGDGVSIPQFGLGTY---------ELPPNEASSVVQSAIELGYRHIDTASLYANE 59 Query: 244 QEIGK 258 +E+G+ Sbjct: 60 REVGR 64 Score = 46.8 bits (106), Expect = 6e-04 Identities = 19/61 (31%), Positives = 37/61 (60%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G K +G+SNF + ++++ + G P QIE+H Q+E+V C+++G+ + + P Sbjct: 134 SGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIELHPWLQQRELVLSCRNDGIQIESWGP 193 Query: 683 F 685 F Sbjct: 194 F 194 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 57.6 bits (133), Expect = 3e-07 Identities = 23/55 (41%), Positives = 36/55 (65%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 V I + V R+ +F+TTK+W + R + ++ +SL+KLG DY+DL L+HWP Sbjct: 45 VGQAIADAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP 99 Score = 39.5 bits (88), Expect = 0.097 Identities = 20/54 (37%), Positives = 32/54 (59%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +PA GLGT+ + KD+ + D V A+ +GYR DTA +Y+ E ++G+ Sbjct: 3 VPAFGLGTF---------RLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQ 47 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 57.6 bits (133), Expect = 3e-07 Identities = 23/76 (30%), Positives = 47/76 (61%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473 R+++F+TTK+WN + + ++ SLK +G++ +DL L+HWP+ D+ ++E Sbjct: 68 RDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPV------PSQDL-YLE 120 Query: 474 TWRGLEDAQRMG*LKA 521 TW+ +D + G +++ Sbjct: 121 TWKAFQDMRDEGLMRS 136 Score = 45.6 bits (103), Expect = 0.001 Identities = 23/62 (37%), Positives = 35/62 (56%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+++ IG SNFN LER++ E P QIE++ Q EM ++ GVV ++P Sbjct: 132 GLMRSIGTSNFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKAHGVVTQAWTPL 191 Query: 686 GS 691 G+ Sbjct: 192 GN 193 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 57.6 bits (133), Expect = 3e-07 Identities = 31/84 (36%), Positives = 46/84 (54%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 AV + + RE+I++TTKL A SL++LGLDY+DLYL+HWP G + Sbjct: 63 AVGRAVNASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWPAGDH 122 Query: 438 ADYSHSDVDFMETWRGLEDAQRMG 509 Y +++W GL A++ G Sbjct: 123 GKY-------IDSWGGLMKAKQDG 139 Score = 41.9 bits (94), Expect = 0.018 Identities = 20/66 (30%), Positives = 31/66 (46%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 670 + +G+ + IG+ NFN + L ++ P QIE+H Q E+ E G+V Sbjct: 134 KAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQIELHPLLNQAELREVNAGYGIVTE 193 Query: 671 GYSPFG 688 Y P G Sbjct: 194 AYGPLG 199 Score = 40.7 bits (91), Expect = 0.042 Identities = 21/65 (32%), Positives = 35/65 (53%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +PS+ +N+G +P +GLG V + + + V A++ GYR DTA+VY E Sbjct: 11 IPSVSLNDGHSIPVLGLG---------VGELSEAEAERSVAAALEAGYRLIDTAAVYGNE 61 Query: 244 QEIGK 258 +G+ Sbjct: 62 AAVGR 66 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 57.6 bits (133), Expect = 3e-07 Identities = 26/74 (35%), Positives = 38/74 (51%) Frame = +2 Query: 461 GLHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVE 640 G+ G + G+ + IG+SNFN LE + K I P QIEVH +E+V+ Sbjct: 115 GVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVD 174 Query: 641 FCQSEGVVVMGYSP 682 FC+ + + YSP Sbjct: 175 FCRKHSIAIQAYSP 188 Score = 54.4 bits (125), Expect = 3e-06 Identities = 20/52 (38%), Positives = 36/52 (69%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 + E V R ++++ TK+++T H + +A + SL LG+DY+DLYL+H+P+ Sbjct: 61 LRESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV 112 Score = 33.9 bits (74), Expect = 4.8 Identities = 18/60 (30%), Positives = 31/60 (51%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +++G +P GLG Y +K + V+ A++ GYR DTA+ Y E+ +G+ Sbjct: 9 LSDGYKIPRFGLGLY---------DLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGE 59 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 57.6 bits (133), Expect = 3e-07 Identities = 26/54 (48%), Positives = 36/54 (66%), Gaps = 2/54 (3%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NAD 443 V R+D+FI TK+WN H +V + +S + L +DYIDL+L+HWPI NAD Sbjct: 81 VTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNAD 134 Score = 53.6 bits (123), Expect = 6e-06 Identities = 27/63 (42%), Positives = 38/63 (60%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +GIVK IG+SN+ L+++L+ IKP QIE+H E+VEFC ++ YSP Sbjct: 168 SGIVKAIGVSNWTIPGLKQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSP 227 Query: 683 FGS 691 GS Sbjct: 228 LGS 230 Score = 44.0 bits (99), Expect = 0.005 Identities = 23/67 (34%), Positives = 33/67 (49%) Frame = +1 Query: 55 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 T+ + +N G +PA+G GT+ G + V +A+DVGYRH D A Y Sbjct: 9 TLSSTTYTLNTGAKIPAVGFGTFANEGAKGETYA-------AVTKALDVGYRHLDCAWFY 61 Query: 235 ETEQEIG 255 E E+G Sbjct: 62 LNEDEVG 68 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 57.2 bits (132), Expect = 5e-07 Identities = 28/73 (38%), Positives = 44/73 (60%), Gaps = 7/73 (9%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS------ 455 RE++F+T+KLW Q T + ++ +S++ L Y+DLYL+HWPI L D S+ Sbjct: 70 REELFVTSKLWMDQV--TRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKPEDF 127 Query: 456 -DVDFMETWRGLE 491 D+D E W+ +E Sbjct: 128 LDMDITEIWQEME 140 Score = 56.0 bits (129), Expect = 1e-06 Identities = 26/61 (42%), Positives = 39/61 (63%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+VK IGLSNF Q+E+++K IKP Q+E+++ Q ++ E C+S +VV Y P Sbjct: 146 GLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELNVYLQQNKLREVCKSYNIVVEAYRPI 205 Query: 686 G 688 G Sbjct: 206 G 206 Score = 41.9 bits (94), Expect = 0.018 Identities = 24/60 (40%), Positives = 35/60 (58%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG+ MPAIGLGT+L + ++ V A++ GYR D A Y+ E+EIG+ Sbjct: 8 LNNGKFMPAIGLGTWL---------AAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 57.2 bits (132), Expect = 5e-07 Identities = 30/83 (36%), Positives = 49/83 (59%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 I+E + RE++F+TTK+ ++ AI+ SL+KL L+Y+DLYL+H P ++ Sbjct: 75 IKESGIPREELFVTTKVITNI---ADIPSAIDQSLRKLQLNYVDLYLIHSPF-----FAK 126 Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521 SD + + W +E Q+ G KA Sbjct: 127 SDGELQQAWAAMEKVQQAGKAKA 149 Score = 50.4 bits (115), Expect = 5e-05 Identities = 24/68 (35%), Positives = 38/68 (55%) Frame = +1 Query: 52 STMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASV 231 S P +K+N+ +P +G GT + + S +++L + + AI +GYRH D A V Sbjct: 5 SIPNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEV 64 Query: 232 YETEQEIG 255 Y TE E+G Sbjct: 65 YGTEAELG 72 Score = 46.4 bits (105), Expect = 8e-04 Identities = 23/72 (31%), Positives = 37/72 (51%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IG+SN+++ LE LK I P QIE H Q+E++ F + + + + Y P Sbjct: 145 GKAKAIGVSNYHQSHLEATLKTAVIAPVINQIEHHPYLQQEELLRFQREKDIKIASYGPL 204 Query: 686 GSLVARHGSTVE 721 ++ G V+ Sbjct: 205 TPILRAPGGPVD 216 >UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Streptococcus agalactiae|Rep: Oxidoreductase, aldo/keto reductase family - Streptococcus agalactiae H36B Length = 245 Score = 56.8 bits (131), Expect = 6e-07 Identities = 26/59 (44%), Positives = 39/59 (66%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 EAV I++ + R++IF+ TKLW + AI+ +LK+L LDYI+LYL+H P+G Sbjct: 56 EAVGRAIKKSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPMG 114 Score = 34.7 bits (76), Expect = 2.8 Identities = 21/60 (35%), Positives = 32/60 (53%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG +P++G G + D +S V+ A+ VGYR DTAS Y E+ +G+ Sbjct: 9 LNNGVKIPSLGFGVFQIDDPLECEQS--------VLDALQVGYRLIDTASGYLNEEAVGR 60 >UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteobacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 274 Score = 56.8 bits (131), Expect = 6e-07 Identities = 22/56 (39%), Positives = 38/56 (67%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 A+ +E +RED+F+TTK+W + + A ++++SL+KL +D +DL L+HWP Sbjct: 52 ALGRALERAGARREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107 Score = 42.7 bits (96), Expect = 0.010 Identities = 17/45 (37%), Positives = 29/45 (64%) Frame = +1 Query: 124 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 LGF GV + D ++ ++ A++ G+RHFDTA +Y+ E +G+ Sbjct: 14 LGF---GVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGR 55 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 56.8 bits (131), Expect = 6e-07 Identities = 28/64 (43%), Positives = 38/64 (59%), Gaps = 2/64 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH--LQNVQKEMVEFCQSEGVVVMGYS 679 G+ K IG+SN + +LE ++K IKP QIE H LQ +V+FC+ +VV GYS Sbjct: 140 GLAKAIGVSNHSPAELETIIKVAKIKPHVNQIEFHPLLQEPTPGIVDFCKQHDIVVEGYS 199 Query: 680 PFGS 691 P S Sbjct: 200 PLAS 203 Score = 56.0 bits (129), Expect = 1e-06 Identities = 27/67 (40%), Positives = 45/67 (67%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M VP +K++NG ++PAIG G+ + + K ++++L D V+ AI+ G+ H DTA Y Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEK-EERELIDAVVSAINAGHLHIDTAEFYG 59 Query: 238 TEQEIGK 258 TE++IG+ Sbjct: 60 TEKQIGE 66 Score = 40.7 bits (91), Expect = 0.042 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Frame = +3 Query: 273 IEEGVVKREDIFITTK-LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS 449 I+E V R+DIF+T+K L+ + ++I++ LK L DY DL+L+H P + +Y Sbjct: 68 IKESGVPRKDIFLTSKTLFGLL--ADDPIESISNQLKTLQTDYFDLFLIHVPPNDDINY- 124 Query: 450 HSDVDFMETWRGLEDAQRMG*LKA 521 D + W LE G KA Sbjct: 125 ----DLAKAWGVLEQLYEKGLAKA 144 >UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 287 Score = 56.4 bits (130), Expect = 8e-07 Identities = 30/89 (33%), Positives = 48/89 (53%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EAV I V R ++FI++K H V +A ++SL+KLGLD++D+++ HWP+ Sbjct: 64 EAVGRGIRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWPVPA 123 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 Y ++ W+GL G +KA Sbjct: 124 LGKY-------VDAWKGLVKLLEEGRVKA 145 Score = 36.7 bits (81), Expect = 0.69 Identities = 20/66 (30%), Positives = 33/66 (50%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++P LK+ +G +P +GLGT+ + + V A+ GYR DTA Y Sbjct: 12 DIPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRN 62 Query: 241 EQEIGK 258 E+ +G+ Sbjct: 63 EEAVGR 68 Score = 34.7 bits (76), Expect = 2.8 Identities = 19/61 (31%), Positives = 30/61 (49%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G VK IG+SNF L+ ++ + PD QI++ + E + G+V +SP Sbjct: 141 GRVKAIGVSNFKPAHLKDIIDATGVVPDVNQIQLSPDLARTEPRAVHRLLGIVTEAWSPI 200 Query: 686 G 688 G Sbjct: 201 G 201 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 56.4 bits (130), Expect = 8e-07 Identities = 24/43 (55%), Positives = 31/43 (72%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 416 V R+ IFIT+KLWNT H V +A+N +LK L DY+DLYL+ Sbjct: 66 VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLV 108 Score = 51.6 bits (118), Expect = 2e-05 Identities = 26/62 (41%), Positives = 38/62 (61%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S K+++G DMPA+GLGT+L SK ++ + V A+ +GYRH D A+ Y E E Sbjct: 6 SFKLSSGYDMPAVGLGTWL---------SKPHEVENAVETALRLGYRHIDAAACYLNENE 56 Query: 250 IG 255 +G Sbjct: 57 VG 58 Score = 42.7 bits (96), Expect = 0.010 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSE--GVVVMGYS 679 G V+ IG+SNF +++E +LK I P QIE H Q + ++ + + ++ + YS Sbjct: 172 GKVRSIGVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYS 231 Query: 680 PFGSLVARHGSTVEGP 727 P G+ + V+ P Sbjct: 232 PLGNNIYNAPRVVDDP 247 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 56.4 bits (130), Expect = 8e-07 Identities = 24/55 (43%), Positives = 35/55 (63%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 V + ++ V RED+F+TTKL + V ++ +SL KLG DY+DL L+HWP Sbjct: 53 VGLGMDAAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP 107 Score = 40.3 bits (90), Expect = 0.056 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 1/109 (0%) Frame = +2 Query: 359 SYKRFTEETRSGLYRSLFDALA-HWIKCRL*SFGRGLHGDLARIGRCSANGIVKGIGLSN 535 S +R T E+ + L D L HW + L L + G+V+ IG+SN Sbjct: 82 SVRRSTRESLNKLGTDYLDLLLIHWPNT---PWMASLSETLGAMNDVVEEGLVRHIGVSN 138 Query: 536 FNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 F+ L+R + Q++ H Q++++++C+ V++ YSP Sbjct: 139 FSPSLLDRARDISSAPIFTDQVQYHPYWDQRKLLDYCRIHDVLLTAYSP 187 Score = 39.9 bits (89), Expect = 0.074 Identities = 20/56 (35%), Positives = 31/56 (55%) Frame = +1 Query: 88 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 G +PA+GLGT+ + + R+ V A+ +GYRH DTA Y E+++G Sbjct: 8 GTSVPALGLGTW---------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVG 54 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 56.0 bits (129), Expect = 1e-06 Identities = 23/51 (45%), Positives = 35/51 (68%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 I VKR++IF+TTK+W Q ++ ++ SL+KLG+D +DL L+HWP Sbjct: 61 IRNSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWP 111 Score = 39.5 bits (88), Expect = 0.097 Identities = 20/53 (37%), Positives = 32/53 (60%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 MPA+G GT+ +NG +V +A+++GYRH DTA +Y E+++G Sbjct: 15 MPALGFGTWQL--ENGTAVP-------LVEKALEIGYRHIDTAQIYGNERDVG 58 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 56.0 bits (129), Expect = 1e-06 Identities = 34/87 (39%), Positives = 52/87 (59%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440 V I + V R++I++T+KL N H +A++DS++KL IDLYL+HWP L Sbjct: 65 VAQGIADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHWP--LPT 121 Query: 441 DYSHSDVDFMETWRGLEDAQRMG*LKA 521 Y DF+ TW+ LE+A+ G L++ Sbjct: 122 LYGG---DFVSTWKVLEEARAAGKLRS 145 Score = 48.0 bits (109), Expect = 3e-04 Identities = 23/69 (33%), Positives = 38/69 (55%) Frame = +1 Query: 52 STMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASV 231 S M VP++ +N+GR++P +G G + + + V A+D+GYRH DTA + Sbjct: 8 SAMTVPTILLNDGREIPQLGFGVF---------QIEPGDTAQAVKTALDLGYRHIDTAQM 58 Query: 232 YETEQEIGK 258 Y E E+ + Sbjct: 59 YGNEAEVAQ 67 Score = 43.2 bits (97), Expect = 0.008 Identities = 22/61 (36%), Positives = 33/61 (54%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G ++ IG+SNF L+R+ +E T+ P QIEVH +E+ C + V +S Sbjct: 139 AAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQIEVHPYFGNEEVRRHCGEHQIGVEAWS 198 Query: 680 P 682 P Sbjct: 199 P 199 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 55.6 bits (128), Expect = 1e-06 Identities = 24/56 (42%), Positives = 35/56 (62%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 V I + V RE++FI++K+WN E A +L+ L LDY+DLYL+HWP+ Sbjct: 60 VGQAILDSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPV 115 Score = 36.7 bits (81), Expect = 0.69 Identities = 21/54 (38%), Positives = 31/54 (57%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +P IGLG + +Q + + +K AI+VGYR FDTA+VY E +G+ Sbjct: 17 IPYIGLGVFQVTEQEFIAGAVEK--------AIEVGYRLFDTAAVYNNEAIVGQ 62 Score = 33.9 bits (74), Expect = 4.8 Identities = 15/58 (25%), Positives = 29/58 (50%) Frame = +2 Query: 509 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 ++K IG++NF + L +L KP Q+E H Q ++ ++ + + +SP Sbjct: 134 LIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSP 191 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 55.6 bits (128), Expect = 1e-06 Identities = 34/89 (38%), Positives = 45/89 (50%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EAV I V R+++FITTK+W V + + SLK+LGLDYIDL L+H P Sbjct: 53 EAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN- 111 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D W +E+ Q G +KA Sbjct: 112 ---------DVYGAWMAMEELQAQGKIKA 131 Score = 45.2 bits (102), Expect = 0.002 Identities = 23/63 (36%), Positives = 33/63 (52%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++K+NNG ++P +G GTY D + V AI GYRH DTA Y E+ Sbjct: 3 TVKLNNGIEVPILGFGTYQITDAG--------EAEQAVKEAIAAGYRHIDTAQSYMNEEA 54 Query: 250 IGK 258 +G+ Sbjct: 55 VGR 57 Score = 41.9 bits (94), Expect = 0.018 Identities = 22/74 (29%), Positives = 37/74 (50%) Frame = +2 Query: 464 LHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 643 ++G + A G +K IG+SNF ++ + I P QIE++ Q + +E Sbjct: 113 VYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQQQSKNIEA 172 Query: 644 CQSEGVVVMGYSPF 685 + EGV V ++PF Sbjct: 173 LRKEGVAVEAWAPF 186 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 55.6 bits (128), Expect = 1e-06 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 4/88 (4%) Frame = +3 Query: 270 KIEEGVVK----REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 K EEGV K +IF+TTKLWN + +A +S + L +DLYL+HWP+ Sbjct: 59 KNEEGVGKGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMPAQ 118 Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521 Y +ETW+ L + ++ G +K+ Sbjct: 119 GQY-------VETWKALVELKKSGRVKS 139 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/62 (33%), Positives = 33/62 (53%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G VK IG+SNF + LER++ + P QIE+H Q+ + EF + + + P Sbjct: 134 SGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELHPDFQQRALREFHEKHNIRTESWRP 193 Query: 683 FG 688 G Sbjct: 194 LG 195 Score = 39.5 bits (88), Expect = 0.097 Identities = 20/62 (32%), Positives = 34/62 (54%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 + ++G MP IGLG + ++ + +VV A+ +GYR DTA +Y+ E+ + Sbjct: 14 ISFHDGHTMPQIGLGVW---------ETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGV 64 Query: 253 GK 258 GK Sbjct: 65 GK 66 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 55.6 bits (128), Expect = 1e-06 Identities = 29/78 (37%), Positives = 47/78 (60%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 + R+++FITTK + T++ +++SL+++GLDY DL L+HWP+G D+D Sbjct: 63 LNRDEVFITTKTMTDGYEDTKIG--LDESLRRIGLDYFDLVLIHWPMG-------HDID- 112 Query: 468 METWRGLEDAQRMG*LKA 521 TW LE A + G +A Sbjct: 113 --TWHALEAAYKAGKTRA 128 Score = 51.2 bits (117), Expect = 3e-05 Identities = 24/62 (38%), Positives = 37/62 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G + IG+SNFN +Q ++ + +++P QIE HL Q +M EF + E +V YSP Sbjct: 124 GKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPL 183 Query: 686 GS 691 G+ Sbjct: 184 GN 185 Score = 39.5 bits (88), Expect = 0.097 Identities = 21/62 (33%), Positives = 31/62 (50%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 L +NN +P G GTY + Q + V+ A + GYR DTA Y+ EQ++ Sbjct: 4 LTLNNDVKIPIFGFGTY---------EISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQV 54 Query: 253 GK 258 G+ Sbjct: 55 GE 56 >UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis Length = 267 Score = 55.6 bits (128), Expect = 1e-06 Identities = 21/55 (38%), Positives = 37/55 (67%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 V I+E + R+++FITTK+W + ++ ++ +S++KL DY+DL L+HWP Sbjct: 45 VGQAIQESGINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP 99 Score = 36.7 bits (81), Expect = 0.69 Identities = 15/39 (38%), Positives = 25/39 (64%) Frame = +1 Query: 142 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 G + +D+ + D V +A+ +GYR DTA +YE E +G+ Sbjct: 9 GTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQ 47 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 55.2 bits (127), Expect = 2e-06 Identities = 21/62 (33%), Positives = 39/62 (62%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G + +GL N ++ QLE V++ GT++P +Q+E H Q +++E+C G+ V+ +SP Sbjct: 532 GWTRTLGLCNVSQTQLETVIETGTVRPALVQVERHPYQPQTDLIEYCHERGIRVVAHSPL 591 Query: 686 GS 691 + Sbjct: 592 SA 593 Score = 52.8 bits (121), Expect = 1e-05 Identities = 22/51 (43%), Positives = 28/51 (54%) Frame = +3 Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 G R +FI K+W T HRR + A SL +LG+D D Y +HWP L Sbjct: 431 GAPDRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEAL 481 >UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reductase; n=4; Saccharomycetales|Rep: NADPH-dependent alpha-keto amide reductase - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 55.2 bits (127), Expect = 2e-06 Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV--HLQNVQKEMVEFCQSEGVVVMGY 676 +G K IG+SNF + L+R+LK +KP QIE LQN + +FCQ ++V Y Sbjct: 148 SGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAY 207 Query: 677 SPFGSL 694 SP G L Sbjct: 208 SPLGPL 213 Score = 41.1 bits (92), Expect = 0.032 Identities = 22/72 (30%), Positives = 34/72 (47%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473 R IF+T K A ++ +LKK+G DY+DLYL+H P + + E Sbjct: 81 RNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPF---VSKEVNGLSLEE 137 Query: 474 TWRGLEDAQRMG 509 W+ +E + G Sbjct: 138 AWKDMEQLYKSG 149 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 54.8 bits (126), Expect = 2e-06 Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 2/90 (2%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IG 431 A++ + + + RED+FIT+KL + + ++ SL++LGL YIDLYL+HWP G Sbjct: 62 ALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQG 120 Query: 432 LNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 L + + ++WR LE+ G +A Sbjct: 121 LPVGDKRNPENRAQSWRVLEEFYSEGKFRA 150 Score = 44.8 bits (101), Expect = 0.003 Identities = 18/64 (28%), Positives = 35/64 (54%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 + G + IG+SN+ + ++ +LK + P +Q+E H + +Q ++ C+ GV YS Sbjct: 144 SEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQVEFHPKLLQNDLRGLCKIRGVCFQAYS 203 Query: 680 PFGS 691 G+ Sbjct: 204 SLGT 207 Score = 42.3 bits (95), Expect = 0.014 Identities = 24/63 (38%), Positives = 32/63 (50%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 PS+ +NN MP +GLGT+ Q + D L+ GYR FDTA+VY E Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALK--------AGYRAFDTAAVYRNEA 57 Query: 247 EIG 255 +G Sbjct: 58 HLG 60 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 54.8 bits (126), Expect = 2e-06 Identities = 22/64 (34%), Positives = 41/64 (64%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A+G+++ IG+SNF Q +ER++++ + P Q+E+H Q ++ ++ G+ + YS Sbjct: 129 ASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYS 188 Query: 680 PFGS 691 PFGS Sbjct: 189 PFGS 192 Score = 47.6 bits (108), Expect = 4e-04 Identities = 18/47 (38%), Positives = 32/47 (68%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 V RE +FIT+K+ + N++L++LG++Y++L+L+HWPI Sbjct: 65 VPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPI 111 Score = 38.3 bits (85), Expect = 0.23 Identities = 21/67 (31%), Positives = 36/67 (53%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M S+ +N+G MP G G +L + ++D + ++ +A+ G+RHFDTA Y Sbjct: 1 MTTDSILLNDGYYMPRPGCGLWL-------IDNRD--VDSLIRQALKAGFRHFDTAQAYF 51 Query: 238 TEQEIGK 258 E +G+ Sbjct: 52 NEDGVGR 58 >UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 263 Score = 54.8 bits (126), Expect = 2e-06 Identities = 23/80 (28%), Positives = 45/80 (56%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 670 +C A G++ +G+SNF+K +E + +E P+ QIE + N + + V++CQ++ ++V Sbjct: 118 QCKAKGLINVVGVSNFDKDMIEILFEETGAYPNLNQIEFNPFNQRWDRVQYCQNKNILVQ 177 Query: 671 GYSPFGSLVARHGSTVEGPR 730 YSP + + E + Sbjct: 178 SYSPIANTLENQTLATEAKK 197 Score = 45.2 bits (102), Expect = 0.002 Identities = 20/56 (35%), Positives = 31/56 (55%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 A+K + +REDI I TK+W A+ +SLK+L + Y+D+ L+H P Sbjct: 47 AIKKYLNSNNQRREDIIIETKIWCDDVEAGNTTNAVLESLKRLNVTYLDIVLIHRP 102 >UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis vadensis ATCC BAA-548|Rep: Aldo/keto reductase - Victivallis vadensis ATCC BAA-548 Length = 287 Score = 54.8 bits (126), Expect = 2e-06 Identities = 25/55 (45%), Positives = 36/55 (65%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 419 E V + ++ ++R D F+T K+W T R +V +A SLK+LG DYIDLYL+H Sbjct: 67 ELVGIAMKGQGIRRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDLYLIH 121 Score = 38.7 bits (86), Expect = 0.17 Identities = 15/73 (20%), Positives = 44/73 (60%), Gaps = 3/73 (4%) Frame = +2 Query: 485 IGRCSANGIVKGIGLSNFNKQQLER--VLKEGTIKPDAIQIEVHLQNVQK-EMVEFCQSE 655 + R G+++ IG+SNF++++L+R + I + + + ++ +++ ++++C+S+ Sbjct: 136 MNRLKREGVIRHIGVSNFSEERLKRAQAASDAPIVANQLHYNLRIREIEQCGLLDYCRSQ 195 Query: 656 GVVVMGYSPFGSL 694 ++V+ + P L Sbjct: 196 DIMVIAWRPLRGL 208 >UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 313 Score = 54.8 bits (126), Expect = 2e-06 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH--LQNVQKEMVEFCQSEGVVVMGYS 679 G K IG+SNF+ + +E +LK IKP QIE + LQN +V +CQ + + YS Sbjct: 150 GKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYS 209 Query: 680 PFGSLVARHGSTVEGP 727 P G L R ++ E P Sbjct: 210 PLGPLQKRPENSNELP 225 Score = 49.6 bits (113), Expect = 9e-05 Identities = 29/84 (34%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRT-EVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS 449 ++E R +IFIT K ++TQ + T + + +N LK LGLDY+DLYL+H P + ++ Sbjct: 74 LKESSKPRSEIFITDK-YSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSPF-FDPEFK 131 Query: 450 HSDVDFMETWRGLEDAQRMG*LKA 521 S + + W+ +E + G K+ Sbjct: 132 GS-LTLEKVWKDMETLYKEGKAKS 154 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 54.4 bits (125), Expect = 3e-06 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 5/94 (5%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW---P 425 +A + ++G KRED+FITTKL+ + + ++ + + +SL +L YIDLYL+ W P Sbjct: 73 QAFQNIFQQGKYKREDVFITTKLFPFKIEK-KIKEVVQNSLDQLQTSYIDLYLIQWSFTP 131 Query: 426 IGLNADYS--HSDVDFMETWRGLEDAQRMG*LKA 521 + N D S + E WR LE+ +G +++ Sbjct: 132 VLTNFDGSVAVNHRPIHEVWRELEECVELGMIRS 165 Score = 49.6 bits (113), Expect = 9e-05 Identities = 24/66 (36%), Positives = 40/66 (60%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++ +++NNG MP +GLGT + V + +++ ++ A+D GYR+FDTA Y Sbjct: 11 DIKYVQLNNGYKMPLLGLGTQ---PYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRN 67 Query: 241 EQEIGK 258 E EIG+ Sbjct: 68 EVEIGQ 73 Score = 41.5 bits (93), Expect = 0.024 Identities = 23/77 (29%), Positives = 38/77 (49%) Frame = +2 Query: 458 RGLHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMV 637 R +H + C G+++ IG++NFN Q + +L IKP QIEV Q +++ Sbjct: 145 RPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIEVTPYLPQIDLI 204 Query: 638 EFCQSEGVVVMGYSPFG 688 F + + + SP G Sbjct: 205 NFLKRCKIETVAISPLG 221 >UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 272 Score = 54.4 bits (125), Expect = 3e-06 Identities = 26/74 (35%), Positives = 43/74 (58%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 V+R+D+F+TTK+W ++ +++ +SL +L L +DL L+HWP +S V Sbjct: 62 VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWP--------NSHVPL 113 Query: 468 METWRGLEDAQRMG 509 ET L A++MG Sbjct: 114 AETLGALSHARQMG 127 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/57 (42%), Positives = 34/57 (59%) Frame = +1 Query: 85 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 NG +PAIGLGT+ + + VV +A+ +GYRH DTA VY+ E+E+G Sbjct: 7 NGARIPAIGLGTW---------ELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVG 54 >UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2; Ostreococcus|Rep: Aldo/keto reductase family proteins - Ostreococcus tauri Length = 336 Score = 54.4 bits (125), Expect = 3e-06 Identities = 26/61 (42%), Positives = 37/61 (60%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G + IG+SN+ L +L+ +KP QIE+H + Q E+ FC+S GV V+GYSP Sbjct: 189 GQCRAIGVSNYELSHLRELLQFCDVKPAVNQIELHARFPQTELRAFCESVGVHVVGYSPL 248 Query: 686 G 688 G Sbjct: 249 G 249 Score = 37.9 bits (84), Expect = 0.30 Identities = 20/57 (35%), Positives = 31/57 (54%) Frame = +1 Query: 88 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 G MP + GTY + + + RD V A+ G++H DTASVY E+++G+ Sbjct: 59 GITMPMLAFGTY---------RLRGETCRDAVRDALRCGFQHVDTASVYGNERDVGE 106 Score = 37.1 bits (82), Expect = 0.52 Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 4/79 (5%) Frame = +3 Query: 297 EDIFITTKLWNTQHR-RTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDV--DF 467 E IF+T+K+ ++ R E A AI ++LG DL L+HWP G + + S+ D Sbjct: 117 ERIFVTSKIAPSEMRSEEEAAAAIAGVNERLGRTP-DLVLVHWP-GRDKESPDSERHRDA 174 Query: 468 ME-TWRGLEDAQRMG*LKA 521 TWR LE+A +MG +A Sbjct: 175 RRWTWRALENALKMGQCRA 193 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 54.4 bits (125), Expect = 3e-06 Identities = 29/58 (50%), Positives = 40/58 (68%), Gaps = 1/58 (1%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKL-WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 ++V I E + RE++FITTKL WN H R VA++ SL+ LG +YIDLYL+H+P Sbjct: 59 KSVGNAIRESGIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFP 113 Score = 52.4 bits (120), Expect = 1e-05 Identities = 22/61 (36%), Positives = 38/61 (62%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G VK IG+SN++ + LE +LK + P Q+E+H Q +++ +C+ +G+ V Y+P Sbjct: 154 GKVKAIGVSNYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPT 213 Query: 686 G 688 G Sbjct: 214 G 214 Score = 47.6 bits (108), Expect = 4e-04 Identities = 22/63 (34%), Positives = 36/63 (57%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 P + +N G MPA+ LG + G + + + Q ++ + A+ GYRH DTA +Y TE+ Sbjct: 5 PPIVLNTGARMPALALGGWAG-----LTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEK 59 Query: 247 EIG 255 +G Sbjct: 60 SVG 62 >UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspergillus fumigatus|Rep: Aldehyde reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 350 Score = 54.4 bits (125), Expect = 3e-06 Identities = 23/48 (47%), Positives = 36/48 (75%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 V RE IF+T+KLWNT H + V +A++ ++K L +Y+DLYL+ +P+G Sbjct: 98 VPREGIFLTSKLWNTHHHPSHVEEALDKTVKDLQTNYLDLYLL-YPLG 144 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 54.0 bits (124), Expect = 4e-06 Identities = 33/92 (35%), Positives = 55/92 (59%), Gaps = 4/92 (4%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHWPIGL 434 A+K + + +KREDIFIT+KL + + + + +++ DSLK L Y+DLYL+HWP G Sbjct: 80 ALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWP-GA 138 Query: 435 NADYSHSDVD---FMETWRGLEDAQRMG*LKA 521 + +S + + TW L + Q+ G L++ Sbjct: 139 SRILENSPDNPKLRVTTWATLVELQQKGLLRS 170 Score = 54.0 bits (124), Expect = 4e-06 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 1/63 (1%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGT-IKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+++ IG+SN+ LE +L+ + +KPD Q+E H Q E++EFC +G+ V YS Sbjct: 166 GLLRSIGVSNYTVGHLEHLLEHCSGVKPDVNQVECHPHFRQDELIEFCTKQGIHVQAYSS 225 Query: 683 FGS 691 G+ Sbjct: 226 LGT 228 Score = 49.2 bits (112), Expect = 1e-04 Identities = 26/69 (37%), Positives = 41/69 (59%) Frame = +1 Query: 49 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228 A T + L++NNG DMP +G+GTY V+ ++ ++ V+ + VG+R DTA Sbjct: 18 ALTPTIRDLRLNNGYDMPLVGIGTY-------KVRGRE-VIKRVIDESFAVGFRSIDTAV 69 Query: 229 VYETEQEIG 255 VY E++IG Sbjct: 70 VYRNEEDIG 78 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 54.0 bits (124), Expect = 4e-06 Identities = 23/51 (45%), Positives = 34/51 (66%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 I + V R+++F+TTK+ H +A SL++LGLDYIDL+L+HWP Sbjct: 64 IRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP 114 Score = 39.5 bits (88), Expect = 0.097 Identities = 22/64 (34%), Positives = 33/64 (51%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 P++ + NG +MP +GLGT+ D + V AI+ GYR DTA Y+ E Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58 Query: 247 EIGK 258 +G+ Sbjct: 59 GVGQ 62 Score = 33.9 bits (74), Expect = 4.8 Identities = 17/61 (27%), Positives = 32/61 (52%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G+V+ IG SNF L + G + P QI++ +++ ++ ++G+V +SP Sbjct: 135 GLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQIQLDPYHLRPDITAIHAAKGIVTESWSPI 193 Query: 686 G 688 G Sbjct: 194 G 194 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 54.0 bits (124), Expect = 4e-06 Identities = 27/68 (39%), Positives = 40/68 (58%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 467 + REDIFITTKL N + +A +S K LG++++DLYL+HWP+ Y+ Sbjct: 71 IPREDIFITTKLRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHWPVPSQGLYT------ 122 Query: 468 METWRGLE 491 E W+ +E Sbjct: 123 -EAWKAME 129 Score = 49.2 bits (112), Expect = 1e-04 Identities = 22/63 (34%), Positives = 35/63 (55%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 AN ++ IG+SNF + L+ +L + P Q+E+H Q+E+ C+ G+ V YS Sbjct: 133 ANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAKCRELGIAVEAYS 192 Query: 680 PFG 688 P G Sbjct: 193 PLG 195 Score = 42.3 bits (95), Expect = 0.014 Identities = 20/64 (31%), Positives = 34/64 (53%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 +P L +NNG +P +G G + + ++ + +V A++ GYRH DTA+ Y E Sbjct: 9 IPQLTLNNGVKIPQLGFGVF---------QVPPEETQRIVEDALEAGYRHIDTAAAYRNE 59 Query: 244 QEIG 255 +G Sbjct: 60 AGVG 63 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 54.0 bits (124), Expect = 4e-06 Identities = 29/79 (36%), Positives = 45/79 (56%), Gaps = 4/79 (5%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G K IGLSNFN + +R+L+ I+P Q+E H Q E++ FC+ E + +M + P Sbjct: 132 SGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQHELLAFCEKEHIHLMAHQP 191 Query: 683 FG----SLVARHGSTVEGP 727 G +VA H + + GP Sbjct: 192 LGGKPVGVVAPH-ADIPGP 209 Score = 52.0 bits (119), Expect = 2e-05 Identities = 26/62 (41%), Positives = 38/62 (61%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S ++ NG +PAIGLGT+ G D N ++++++V AI GYRH D A+ Y E+ Sbjct: 7 SFRLVNGSTLPAIGLGTFQGDDGN-------EKVKNIVKAAIQAGYRHIDGAAAYGNEEA 59 Query: 250 IG 255 IG Sbjct: 60 IG 61 Score = 35.9 bits (79), Expect = 1.2 Identities = 27/89 (30%), Positives = 45/89 (50%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EA+ I+E + R+++ + W H +V +A++ SL+ LGL+Y+ + P Sbjct: 58 EAIGDAIKESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYVPHAYLPGP--N 109 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 N DY S + ETW+ +E G KA Sbjct: 110 NVDYERSR-KYTETWQAMEKLVDSGKAKA 137 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 54.0 bits (124), Expect = 4e-06 Identities = 26/61 (42%), Positives = 38/61 (62%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G +K IG+SNFN +LER+L I P QIE+H Q E+V FC++ G+ ++ + P Sbjct: 193 GKLKMIGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVRFCKANGIHLVAHQPL 252 Query: 686 G 688 G Sbjct: 253 G 253 Score = 43.6 bits (98), Expect = 0.006 Identities = 23/53 (43%), Positives = 32/53 (60%) Frame = +1 Query: 100 PAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 PA+GLGT+ G N VK + V++A+ GYRH DTA+ Y E E+G+ Sbjct: 47 PAVGLGTFQGDAGNRGVK-------EAVLQALRCGYRHIDTATAYGNEIEVGE 92 Score = 41.1 bits (92), Expect = 0.032 Identities = 19/42 (45%), Positives = 31/42 (73%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDY 398 I+E + RE+I +TTKL T HR ++V +A++ SL++L L+Y Sbjct: 94 IKESRIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNY 135 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 53.6 bits (123), Expect = 6e-06 Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH--WPIG 431 +V I + + RE IF+TTKL + SLK LGLDY+DLYL+H WP G Sbjct: 58 SVGQAIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWG 117 Query: 432 -LNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 + Y +++D W+ +E + G KA Sbjct: 118 QVGRVYDEANLD---VWQAMEAIYQSGRAKA 145 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 53.6 bits (123), Expect = 6e-06 Identities = 26/75 (34%), Positives = 42/75 (56%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G V+ IG+SNF ++ LE +LK KP A QI H+ N ++++C+ + ++ YSP Sbjct: 148 GKVRSIGVSNFLQKDLENILKNCKTKPAANQILCHIGNTPFTLLDYCKKQNILAEAYSPI 207 Query: 686 GSLVARHGSTVEGPR 730 HG ++ PR Sbjct: 208 A-----HGELLKDPR 217 Score = 50.4 bits (115), Expect = 5e-05 Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 4/83 (4%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA---- 440 + + +KRE++FIT+K+ + +I+ SLK + LD+IDL L+H P N+ Sbjct: 69 VRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNSFRKG 128 Query: 441 DYSHSDVDFMETWRGLEDAQRMG 509 DY +V E + LEDAQ+ G Sbjct: 129 DYFKENV---EVYNALEDAQKAG 148 Score = 42.7 bits (96), Expect = 0.010 Identities = 25/60 (41%), Positives = 34/60 (56%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +NNG +P +GLGT+ D N VV++ V A VGYRH DTA Y E+ +G+ Sbjct: 17 LNNGNKIPKLGLGTWR-IDDN-VVEA-------AVREAFKVGYRHIDTAQAYGNERGVGE 67 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 53.6 bits (123), Expect = 6e-06 Identities = 29/79 (36%), Positives = 42/79 (53%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 I + R ++FITTKL + ++ SLK+LGLDY+DL L+HWP+ Sbjct: 61 IRSSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL------PR 114 Query: 453 SDVDFMETWRGLEDAQRMG 509 D +F+ TW+ E Q G Sbjct: 115 RD-EFISTWKTFERLQADG 132 Score = 43.6 bits (98), Expect = 0.006 Identities = 23/63 (36%), Positives = 35/63 (55%) Frame = +1 Query: 67 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 246 P +++N+G +P IGLGT+ D Q+ V+ A++ GYRH DTA Y E+ Sbjct: 5 PVIELNDGHRIPQIGLGTW---------PLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEK 55 Query: 247 EIG 255 +G Sbjct: 56 GVG 58 Score = 42.3 bits (95), Expect = 0.014 Identities = 22/67 (32%), Positives = 35/67 (52%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 670 R A+G V+ IG+SNF LER++ + P QI+V + + + + G+V Sbjct: 127 RLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQVSPAITRIVDIAYNRRHGIVTE 186 Query: 671 GYSPFGS 691 YSP G+ Sbjct: 187 SYSPLGA 193 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 53.6 bits (123), Expect = 6e-06 Identities = 32/83 (38%), Positives = 46/83 (55%), Gaps = 1/83 (1%) Frame = +3 Query: 276 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL-GLDYIDLYLMHWPIGLNADYSH 452 + G KRE+IF TTKLWN+Q+ AI L ++ GL YIDL L+H P+ Sbjct: 67 DPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-------E 119 Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521 +ETWR +++A G +K+ Sbjct: 120 GSKLRLETWRAMQEAVDEGLVKS 142 Score = 47.6 bits (108), Expect = 4e-04 Identities = 22/61 (36%), Positives = 41/61 (67%), Gaps = 2/61 (3%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLK--EGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 G+VK IG+SN+ K+ ++ +L E KP QIE+ +++E+ ++C+S+G+VV ++ Sbjct: 138 GLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELADYCKSKGLVVEAFA 197 Query: 680 P 682 P Sbjct: 198 P 198 Score = 46.0 bits (104), Expect = 0.001 Identities = 24/60 (40%), Positives = 36/60 (60%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 K++NG +P+I LGTY + +S Q ++V + GYRHFDTA +Y E+E+G Sbjct: 7 KLSNGFKIPSIALGTY------DIPRS---QTAEIVYEGVKCGYRHFDTAVLYGNEKEVG 57 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 53.2 bits (122), Expect = 7e-06 Identities = 32/89 (35%), Positives = 45/89 (50%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 EAV I V R+++FITTK+W V + + SLK+LGLDY+DL L+H P Sbjct: 53 EAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFN- 111 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D W +E+ Q G ++A Sbjct: 112 ---------DVYGAWIAMEELQASGKIRA 131 Score = 44.0 bits (99), Expect = 0.005 Identities = 23/63 (36%), Positives = 33/63 (52%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++K+NNG ++P +G GTY D + V AI GYRH DTA Y E+ Sbjct: 3 TVKLNNGVEVPILGFGTYQITDA--------AEAEHAVKDAIKAGYRHIDTAQSYMNEEA 54 Query: 250 IGK 258 +G+ Sbjct: 55 VGR 57 Score = 37.5 bits (83), Expect = 0.39 Identities = 19/74 (25%), Positives = 37/74 (50%) Frame = +2 Query: 464 LHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 643 ++G + A+G ++ IG+SNF+ ++ + + P QIEV+ Q + Sbjct: 113 VYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQTANLAI 172 Query: 644 CQSEGVVVMGYSPF 685 + EGV + ++PF Sbjct: 173 LRKEGVAIEAWAPF 186 >UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 289 Score = 53.2 bits (122), Expect = 7e-06 Identities = 30/85 (35%), Positives = 47/85 (55%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 E V + I+E V RE +FIT K+ ++ AI+ SL+K+ +Y DLYL+H P Sbjct: 52 EEVAIAIKESGVPREKLFITNKV---AQGIDDIEAAIDQSLQKMQTNYFDLYLIHIPF-- 106 Query: 435 NADYSHSDVDFMETWRGLEDAQRMG 509 ++ S+ DF W+ +E Q+ G Sbjct: 107 ---FAKSEEDFQRAWKTMEGIQKAG 128 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 52.8 bits (121), Expect = 1e-05 Identities = 25/59 (42%), Positives = 37/59 (62%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+ KG+G+SNFN Q + +L IKP QIE+H+ N QK +VEF + + + +SP Sbjct: 147 GLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNLVEFLKKVNIYPVAFSP 205 Score = 51.2 bits (117), Expect = 3e-05 Identities = 28/69 (40%), Positives = 45/69 (65%), Gaps = 1/69 (1%) Frame = +1 Query: 52 STMEVPS-LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 228 S+ E+ + ++NG+ MPA GLG+ V+S + ++ +++ +A+DVGYRH DTA Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS-------SRVQSVE-EVTNLIRKALDVGYRHIDTAQ 53 Query: 229 VYETEQEIG 255 +YE EQ IG Sbjct: 54 MYENEQFIG 62 Score = 47.2 bits (107), Expect = 5e-04 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 4/88 (4%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 A+K EG KREDIF+ TK + + + + L+KL +DY+DL L+H P+ Sbjct: 64 ALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAP 121 Query: 438 AD----YSHSDVDFMETWRGLEDAQRMG 509 +D ++H V + W E+ +G Sbjct: 122 SDDYQQWNHKPVH--QIWAEFEEIHSLG 147 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 52.8 bits (121), Expect = 1e-05 Identities = 21/45 (46%), Positives = 33/45 (73%) Frame = +3 Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 KRE +++TTKL ++Q +A ++SLK L LDY+D+Y++HWP Sbjct: 78 KRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWP 122 Score = 46.4 bits (105), Expect = 8e-04 Identities = 22/59 (37%), Positives = 34/59 (57%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+ + +G+ NF L+R+ +E P QIE+H Q+E+V FC+ G+ V YSP Sbjct: 143 GMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSP 201 Score = 43.2 bits (97), Expect = 0.008 Identities = 24/65 (36%), Positives = 34/65 (52%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 VP + + +G +P +GLG L D GVV VV A++ GYRH D A+ Y E Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVP--------VVESALEAGYRHIDGAAGYNNE 61 Query: 244 QEIGK 258 +G+ Sbjct: 62 AGVGR 66 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 52.8 bits (121), Expect = 1e-05 Identities = 27/76 (35%), Positives = 43/76 (56%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 473 RE + IT+KL H + I +SL + LDY DLYL+HWP + D+ ++E Sbjct: 69 REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPNPI------QDI-YVE 121 Query: 474 TWRGLEDAQRMG*LKA 521 W+ L +A+R G +++ Sbjct: 122 AWQALIEAKRRGYIRS 137 Score = 39.9 bits (89), Expect = 0.074 Identities = 22/66 (33%), Positives = 35/66 (53%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 ++P++ +++G +P +G GTY +GV + AID GYR DTA YE Sbjct: 4 QIPNVTLHDGLTIPKVGFGTYRLNGNDGV---------QAINNAIDHGYRLIDTAYNYEN 54 Query: 241 EQEIGK 258 E +G+ Sbjct: 55 EGTVGE 60 Score = 33.9 bits (74), Expect = 4.8 Identities = 18/59 (30%), Positives = 31/59 (52%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G ++ IG+ NF + LER+ +E P QIE+H Q++ ++ Q + +SP Sbjct: 133 GYIRSIGVCNFLPEHLERLKQETGELPTINQIELHPFFNQEDQRKWHQEHQIATESWSP 191 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 52.4 bits (120), Expect = 1e-05 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 3/96 (3%) Frame = +2 Query: 449 SFGRGLHGDLARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQK 628 +F R L G + + A+G V+ IG+SNF + L R+L E +I P QIEVH Q+ Sbjct: 129 AFDRTL-GAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQR 187 Query: 629 EMVEFCQSEGVVVMGYSPFGSLVARHG---STVEGP 727 + G++ +SP G + G ST+E P Sbjct: 188 ALQRLHAEHGILTQAWSPIGGITFYRGGEKSTLEDP 223 Score = 46.8 bits (106), Expect = 6e-04 Identities = 20/52 (38%), Positives = 31/52 (59%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 I + R+++FI TK+W + + E A + S KLG+D IDL L+H P+ Sbjct: 75 IRRAGIARDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPL 126 Score = 38.3 bits (85), Expect = 0.23 Identities = 20/58 (34%), Positives = 32/58 (55%) Frame = +1 Query: 85 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +G +MP IGLG + ++ + V A+ +GYRH DTA+ Y E+E+G+ Sbjct: 25 SGVEMPMIGLGVF---------QTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGE 73 >UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Lactococcus lactis|Rep: Oxidoreductase, aldo/keto reductase family - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 281 Score = 52.0 bits (119), Expect = 2e-05 Identities = 24/62 (38%), Positives = 37/62 (59%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G VK IG+SNF+ ++L + IKP A+Q+E H + QKE+ EF + G + + P Sbjct: 125 SGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPYHQQKELQEFLKPYGTKIESWYP 184 Query: 683 FG 688 G Sbjct: 185 LG 186 Score = 38.3 bits (85), Expect = 0.23 Identities = 19/60 (31%), Positives = 31/60 (51%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 +N+G +P GLG Y + + + V A+ +GYRH DTA Y+ E+ +G+ Sbjct: 7 LNDGNIIPQFGLGVYQ--------IPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGR 58 Score = 38.3 bits (85), Expect = 0.23 Identities = 26/88 (29%), Positives = 45/88 (51%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 +V I + +I+IT+KLW + + + +QAI L+ L L IDL L+H +G Sbjct: 55 SVGRAIHSSGIPISEIWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLHQQVG-- 110 Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521 ++ + W LE+A + G +K+ Sbjct: 111 --------NYRKAWIALENAVKSGKVKS 130 >UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfataricus|Rep: Oxidoreductase - Sulfolobus solfataricus Length = 304 Score = 52.0 bits (119), Expect = 2e-05 Identities = 24/45 (53%), Positives = 30/45 (66%) Frame = +3 Query: 291 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 KRED+FI TK+ R +V +A SLK+L YIDLYL+HWP Sbjct: 72 KREDLFIITKVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWP 116 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 51.6 bits (118), Expect = 2e-05 Identities = 22/47 (46%), Positives = 32/47 (68%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 428 + R ++FITTK+ + R V Q+++ SL LG DYIDL L+HWP+ Sbjct: 90 IDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWPV 136 Score = 48.0 bits (109), Expect = 3e-04 Identities = 26/66 (39%), Positives = 39/66 (59%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 +VP++K+NNG +MP +G+GT+L D + V AI VG+R DTA Y Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFLVKD----------NAAERVCHAIKVGFRLIDTAQGYGN 77 Query: 241 EQEIGK 258 E+E+G+ Sbjct: 78 EKEVGE 83 Score = 44.0 bits (99), Expect = 0.005 Identities = 20/61 (32%), Positives = 34/61 (55%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G ++ IG+SNFN L+ +L+ I+P QIE+ Q ++V + +G+ V + P Sbjct: 154 GKIRSIGVSNFNPHHLDELLEYARIRPVVNQIEIEPYMTQHDVVGYTFRKGIQVEAWGPL 213 Query: 686 G 688 G Sbjct: 214 G 214 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 51.6 bits (118), Expect = 2e-05 Identities = 22/63 (34%), Positives = 37/63 (58%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G + IG+SNF+ L+ V++ IKP QI + + Q+++ FCQ G++V YSP Sbjct: 140 SGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQEDVTAFCQDNGILVEAYSP 199 Query: 683 FGS 691 + Sbjct: 200 LAT 202 Score = 47.6 bits (108), Expect = 4e-04 Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 3/92 (3%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH--WPI 428 E+V + + + R DIF+T+KL + + ++++ GL+ +DLYL+H WP Sbjct: 57 ESVGKAVRDSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPW 116 Query: 429 G-LNADYSHSDVDFMETWRGLEDAQRMG*LKA 521 ADY+ ++ E W+ +E+ G +A Sbjct: 117 SEKGADYTKENI---EVWKAMEEIYESGRCRA 145 Score = 36.3 bits (80), Expect = 0.91 Identities = 23/60 (38%), Positives = 30/60 (50%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 + NG +P IGLGT+ NG + V A+ GYRH DTA Y E+ +GK Sbjct: 10 LENGVAIPKIGLGTWQV--PNG------ETTYHAVSFALKNGYRHIDTAYAYHNEESVGK 61 >UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteobacteria|Rep: Aldo/keto reductase - Shewanella sp. (strain ANA-3) Length = 280 Score = 51.6 bits (118), Expect = 2e-05 Identities = 28/80 (35%), Positives = 44/80 (55%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +AV I + RE++FITTK+W + ++ DSL L Y+DL L+HWP L Sbjct: 57 QAVGDAINTSGIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWP--L 114 Query: 435 NADYSHSDVDFMETWRGLED 494 N+D S V+++ + + D Sbjct: 115 NSD-EPSMVEYLSELKAVLD 133 Score = 48.0 bits (109), Expect = 3e-04 Identities = 24/63 (38%), Positives = 38/63 (60%), Gaps = 3/63 (4%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLER---VLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 676 G+ + IG+SNF QL + +L EG I + Q+EVH + +++ +FC+ V+V GY Sbjct: 135 GLTRRIGVSNFTNAQLAQAIAILGEGVIYTN--QVEVHPYLINRKVTDFCRQHNVLVTGY 192 Query: 677 SPF 685 PF Sbjct: 193 MPF 195 Score = 38.7 bits (86), Expect = 0.17 Identities = 16/38 (42%), Positives = 22/38 (57%) Frame = +1 Query: 142 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 G + KD D V+ A++ G RH DTA +Y EQ +G Sbjct: 23 GTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVG 60 >UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Sulfolobaceae|Rep: Oxidoreductase, aldo/keto reductase family - Sulfolobus solfataricus Length = 265 Score = 51.6 bits (118), Expect = 2e-05 Identities = 20/44 (45%), Positives = 31/44 (70%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 R+ IFI TK+W+ + ++ ++ +SLK+L YIDLYL+HWP Sbjct: 72 RDKIFIITKVWSNHLKYDDLIRSAKNSLKRLNAKYIDLYLIHWP 115 Score = 44.0 bits (99), Expect = 0.005 Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVL---KEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 676 GIV IG+SNF+ + LE + K+ I + I+ V ++ +K+++ FC+ + V+ Y Sbjct: 135 GIVNCIGVSNFDIKLLEETMSITKKYEITANEIEYNVENKSAEKDVIPFCERNNIKVIAY 194 Query: 677 SPFGSLVARHGSTVE 721 SP A++ +E Sbjct: 195 SPLARGNAKNNKILE 209 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 51.2 bits (117), Expect = 3e-05 Identities = 27/86 (31%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 +A++ +EG KRED+F+ TKL++ ++ T+V + SL+ L +YIDLYL+H+ Sbjct: 61 DALQEIYKEGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSP 118 Query: 435 NAD-YSHSDVDFMETWRGLEDAQRMG 509 D + + + W E+ + G Sbjct: 119 PTDQFELTHKPVFQVWAEFEELVQKG 144 Score = 46.8 bits (106), Expect = 6e-04 Identities = 25/57 (43%), Positives = 35/57 (61%) Frame = +1 Query: 85 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 NG +P GLGTY V SK++ + + A+D+GYRH DTA +YE E++IG Sbjct: 12 NGSKLPVFGLGTYK-------VVSKEEMVT-FLRTALDLGYRHIDTAIMYENEKQIG 60 Score = 46.8 bits (106), Expect = 6e-04 Identities = 23/59 (38%), Positives = 34/59 (57%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+++ IG+SNFN Q L + IKP QIEV++ Q ++EFC+ + V Y P Sbjct: 144 GLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYCQQPRLLEFCKKLNLHVTAYCP 202 >UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; Ostreococcus|Rep: Glycerol dehydrogenase, putative - Ostreococcus tauri Length = 425 Score = 51.2 bits (117), Expect = 3e-05 Identities = 22/67 (32%), Positives = 43/67 (64%) Frame = +2 Query: 479 ARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEG 658 A + +C A+G VK +G++NF+ +ER++K +KP ++E+H Q+++V C+ G Sbjct: 245 AALEKCVADGRVKALGVANFSVPAVERLMKCCKVKPAVNEVELHPLLAQRKLVGVCRRYG 304 Query: 659 VVVMGYS 679 V V+ ++ Sbjct: 305 VTVLAHT 311 Score = 44.4 bits (100), Expect = 0.003 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 2/78 (2%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD--F 467 R+ +F++ KL +H+ + A ++ L LG++Y+DL+ + WP+ + D + Sbjct: 183 RQSVFVSAKLRPDEHKSVDAA--LSAILSALGIEYLDLFSLEWPVVHKPGTTEVDSEGSL 240 Query: 468 METWRGLEDAQRMG*LKA 521 ETW LE G +KA Sbjct: 241 EETWAALEKCVADGRVKA 258 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 51.2 bits (117), Expect = 3e-05 Identities = 26/57 (45%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHR-RTEVAQAINDSLKKLGLDYIDLYLMHWP 425 A+K + + +KREDIFIT+KL + + V Q + SL L DY+DLYL+HWP Sbjct: 88 ALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144 Score = 46.0 bits (104), Expect = 0.001 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 4/90 (4%) Frame = +2 Query: 485 IGRCSANGIVKGIGLSNFNKQQLERVLKEGT-IKPDAIQIEVHLQNVQKEMVEFCQSEGV 661 + + G ++ IG+SN+ + L+ +L + I P Q+E H Q E++E+C+ G+ Sbjct: 177 LSKLEREGCLRSIGVSNYTVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCRQHGI 236 Query: 662 VVMGYSPFGS---LVARHGSTVEGPRSTIQ 742 + YS GS R TV+ ++Q Sbjct: 237 FLQAYSSLGSSNTAELREDETVQSVAKSLQ 266 Score = 43.2 bits (97), Expect = 0.008 Identities = 24/62 (38%), Positives = 32/62 (51%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 + K+N G D+P G GTY Q + + D A++ GYRH DTA VY E+ Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQELIYQVLDY--------ALEAGYRHIDTAVVYRNEEY 84 Query: 250 IG 255 IG Sbjct: 85 IG 86 >UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 274 Score = 51.2 bits (117), Expect = 3e-05 Identities = 23/62 (37%), Positives = 38/62 (61%), Gaps = 2/62 (3%) Frame = +2 Query: 512 VKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 ++ +G+SNF + LER+L + + K P QIE+H N +++ +C +G+ GYSP Sbjct: 122 IRNLGVSNFGIKNLERLLNDPSCKIVPAVNQIELHPGNPSPKLIAYCAEKGIHCSGYSPL 181 Query: 686 GS 691 GS Sbjct: 182 GS 183 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 50.8 bits (116), Expect = 4e-05 Identities = 28/83 (33%), Positives = 46/83 (55%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 I++ + RE +F+T+K+ + +A+ SLK+L DY+DL L+HWP+ H Sbjct: 65 IQQLGLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPV-----REH 119 Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521 F +TWR LE + G +K+ Sbjct: 120 ----FFDTWRALEQLKADGQVKS 138 Score = 44.0 bits (99), Expect = 0.005 Identities = 24/60 (40%), Positives = 31/60 (51%) Frame = +1 Query: 76 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 K+ +GR MP +G GTYL DQ + + A D GYR FDTA +Y E +G Sbjct: 11 KLADGRQMPVMGFGTYLLNDQ--------PTMNTAIQTAWDAGYRMFDTAMLYRNEDILG 62 Score = 39.5 bits (88), Expect = 0.097 Identities = 21/66 (31%), Positives = 33/66 (50%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A+G VK IG+SN+ LE + + P Q+E H Q+ + ++ Q +V +S Sbjct: 132 ADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADYDQEHDIVTEAWS 191 Query: 680 PFGSLV 697 P G V Sbjct: 192 PLGRRV 197 >UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 264 Score = 50.8 bits (116), Expect = 4e-05 Identities = 21/59 (35%), Positives = 36/59 (61%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G+++ +G+SNF LE + K G P QIE++ Q+E++++C G+ V GY+P Sbjct: 135 GLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGYAP 193 Score = 48.0 bits (109), Expect = 3e-04 Identities = 19/51 (37%), Positives = 34/51 (66%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 + + +KREDI++TTKL ++ + + +S+KKL + Y+DL+L+H P Sbjct: 66 VRKSGLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTP 116 Score = 39.5 bits (88), Expect = 0.097 Identities = 21/59 (35%), Positives = 31/59 (52%) Frame = +1 Query: 79 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 +N+GR MP GLG + + DV + A+ GYR DTA +Y+ E+E+G Sbjct: 15 LNDGRKMPLFGLGVF----------RLETGCEDVCLFALKNGYRMLDTADIYQNEKEVG 63 >UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=3; Archaea|Rep: 2,5-diketo-D-gluconic acid reductase A - Sulfolobus acidocaldarius Length = 267 Score = 50.8 bits (116), Expect = 4e-05 Identities = 21/44 (47%), Positives = 29/44 (65%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 RE +FITTK+W + + ++ SLK+L YIDLYL+HWP Sbjct: 72 RESLFITTKVWPNHLKYDDTIKSALASLKRLNTKYIDLYLIHWP 115 Score = 39.5 bits (88), Expect = 0.097 Identities = 18/64 (28%), Positives = 38/64 (59%), Gaps = 3/64 (4%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVL---KEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 676 G+V+ IG+SNF+ + L++ + K+ I + IQ ++ +++++ F + V ++ Y Sbjct: 135 GVVRCIGVSNFDVKLLDQAIHSTKKYEIVANQIQYSIYRLTPERDVIPFAEKNKVTIIAY 194 Query: 677 SPFG 688 SP G Sbjct: 195 SPLG 198 >UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 665 Score = 50.8 bits (116), Expect = 4e-05 Identities = 21/51 (41%), Positives = 28/51 (54%) Frame = +3 Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 434 G RE +F+ K W T HRR + A S ++LG+D D Y +HWP L Sbjct: 429 GAPDRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSAL 479 Score = 48.8 bits (111), Expect = 2e-04 Identities = 21/62 (33%), Positives = 35/62 (56%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G + +G+ N ++ QLE VL+ G I P +Q+E H + +VE C G+ V+ +SP Sbjct: 530 GWARTLGICNVSRAQLETVLETGEIDPALVQVERHPYRPRNGLVELCHGRGIRVVAHSPL 589 Query: 686 GS 691 + Sbjct: 590 SA 591 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 50.4 bits (115), Expect = 5e-05 Identities = 28/67 (41%), Positives = 39/67 (58%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M VPS+++ +G MP +GLGTY D +QL+ V A+ GYR FDTA+VY Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYKLQDH--------EQLKQSVSCALQAGYRAFDTAAVYG 52 Query: 238 TEQEIGK 258 E +G+ Sbjct: 53 NEAHLGQ 59 Score = 49.2 bits (112), Expect = 1e-04 Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHSDVDF 467 RED+FI +KL + H + SL++L +YIDLYL+HWP GL+ + S Sbjct: 72 REDVFIISKLAPSDHG-LRAKEGCLRSLEQLDCEYIDLYLIHWPGMEGLDPEDSRHSEYR 130 Query: 468 METWRGLEDAQRMG*LKA 521 ++W LE+ G KA Sbjct: 131 AQSWATLEEFHASGQFKA 148 Score = 44.4 bits (100), Expect = 0.003 Identities = 19/63 (30%), Positives = 33/63 (52%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A+G K IG+SN+ + + +L + P +QIE + +Q+E+ + C G+ YS Sbjct: 142 ASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQIECQPKLIQRELRDLCMETGIHFQAYS 201 Query: 680 PFG 688 G Sbjct: 202 SLG 204 >UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreductase; n=1; Mycoplasma penetrans|Rep: Aldo/keto reductase family oxidoreductase - Mycoplasma penetrans Length = 266 Score = 50.4 bits (115), Expect = 5e-05 Identities = 23/67 (34%), Positives = 41/67 (61%) Frame = +2 Query: 494 CSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 673 C G+V IG+SNF++ LE + + + P + QIE+ + N++++ V + S+G+ V Sbjct: 116 CQKEGLVGEIGVSNFDRDALEIMRQRTGVYPLSNQIELSVNNLREDRVVYNHSKGIEVQA 175 Query: 674 YSPFGSL 694 +SP G L Sbjct: 176 WSPLGDL 182 >UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 107 Score = 50.4 bits (115), Expect = 5e-05 Identities = 25/67 (37%), Positives = 42/67 (62%), Gaps = 1/67 (1%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLG-FDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 ++P + + +G +MP IG+GT F Q +L +++ AI+VGYRHFDTA+ Y Sbjct: 6 QIPGVLLRSGXEMPLIGMGTATSPFPQ-------PHRLTSILVDAIEVGYRHFDTAAHYA 58 Query: 238 TEQEIGK 258 +E+ +G+ Sbjct: 59 SEEPLGR 65 >UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 289 Score = 50.0 bits (114), Expect = 7e-05 Identities = 22/48 (45%), Positives = 34/48 (70%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 VKRE+IF+TTK+W + + R +++ +SLK+L Y+DL L+H P G Sbjct: 68 VKREEIFLTTKVWVSNYER--CYESVIESLKRLDTSYLDLILLHQPFG 113 Score = 43.6 bits (98), Expect = 0.006 Identities = 23/67 (34%), Positives = 34/67 (50%) Frame = +1 Query: 55 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 T V + +NNG +P+IG G + + ++ D V +AI +GYR DTA Y Sbjct: 3 TSNVKLITLNNGNKIPSIGFGVF---------QIPKEETADCVKKAISIGYRLIDTAQAY 53 Query: 235 ETEQEIG 255 E+E G Sbjct: 54 HNEKETG 60 >UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 138 Score = 50.0 bits (114), Expect = 7e-05 Identities = 21/54 (38%), Positives = 35/54 (64%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 416 E + I++ V R++IF+T+K+WN H+ Q I++ LK+L DY+DL L+ Sbjct: 57 ELIGKAIKDSGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110 Score = 49.2 bits (112), Expect = 1e-04 Identities = 26/62 (41%), Positives = 38/62 (61%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 LK+ NG ++P IGLGTY D++ V ++ ++ A+ GYRH DTA +Y E+ I Sbjct: 8 LKLFNGVEIPLIGLGTYKMTDEHEVYQA--------IITALQNGYRHIDTAQIYGNEELI 59 Query: 253 GK 258 GK Sbjct: 60 GK 61 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 50.0 bits (114), Expect = 7e-05 Identities = 25/83 (30%), Positives = 44/83 (53%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 + +GV + DIF+ TK+WN +A L++LG +++D+ L+HWP Sbjct: 57 VGKGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC------PE 110 Query: 453 SDVDFMETWRGLEDAQRMG*LKA 521 D F++TW+ L + + G K+ Sbjct: 111 KD-QFVDTWKALIELRDAGKAKS 132 Score = 48.4 bits (110), Expect = 2e-04 Identities = 22/61 (36%), Positives = 36/61 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G K IG+SNF ++ L+R++ E + P QIE+H Q++M + + G+V +SP Sbjct: 128 GKAKSIGVSNFREEDLKRIIDETGVTPALNQIELHPSFQQRDMRKVHEDLGIVTQSWSPL 187 Query: 686 G 688 G Sbjct: 188 G 188 Score = 46.0 bits (104), Expect = 0.001 Identities = 23/66 (34%), Positives = 38/66 (57%) Frame = +1 Query: 61 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 240 + P+L +N+GR +P +G GT+ + +++ V AIDVGY DTA++Y Sbjct: 3 DYPTLNLNDGRQIPQLGFGTW---------QMEEEDAPQAVSTAIDVGYWLIDTAAIYGN 53 Query: 241 EQEIGK 258 E+ +GK Sbjct: 54 EKGVGK 59 >UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized protein - Sulfitobacter sp. NAS-14.1 Length = 274 Score = 50.0 bits (114), Expect = 7e-05 Identities = 22/57 (38%), Positives = 33/57 (57%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 E V + V+R+++F+TTK+ A + SLK+LG DY+DL L+HWP Sbjct: 51 EQVGEGLRRADVRRDEVFLTTKILPEHFSPEAFTAAADASLKRLGTDYVDLLLLHWP 107 Score = 37.1 bits (82), Expect = 0.52 Identities = 16/45 (35%), Positives = 27/45 (60%) Frame = +1 Query: 124 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGK 258 LGF G + + + D+V A+ G+RH DTA Y+ E+++G+ Sbjct: 14 LGF---GTFQLEQDTVADMVAAALSEGFRHIDTAQAYQNEEQVGE 55 >UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 153 Score = 50.0 bits (114), Expect = 7e-05 Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 1/76 (1%) Frame = +3 Query: 267 MKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-NAD 443 +K + V +E I+ ++WN+ H V + +++ LG+ Y+DLYL+HWPI NA+ Sbjct: 3 LKFLKSVKLKEKIYFI-QVWNSCHNSNLVIKHCEKTIEDLGIGYLDLYLIHWPIAFKNAN 61 Query: 444 YSHSDVDFMETWRGLE 491 S +D+++ G + Sbjct: 62 PSDVTIDWIKDENGYQ 77 >UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 259 Score = 50.0 bits (114), Expect = 7e-05 Identities = 27/65 (41%), Positives = 40/65 (61%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 A G V+ IG+SNF+ QL +L+ GT P QI+ +L + E+VEFC++ G++V Y Sbjct: 141 ATGKVRYIGVSNFDIPQLNTLLEIGT--PTINQIQYYLGSDNLEVVEFCKNHGILVEAYG 198 Query: 680 PFGSL 694 P L Sbjct: 199 PLTPL 203 Score = 41.1 bits (92), Expect = 0.032 Identities = 19/51 (37%), Positives = 32/51 (62%), Gaps = 1/51 (1%) Frame = +1 Query: 106 IGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 IG GT + + G +++K ++ D++ A+ +GY H DTA VY T+ E+G Sbjct: 15 IGTGTSIKDLKRGQPTAENKARIVDILRYALSIGYNHIDTAEVYTTQPEVG 65 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 49.6 bits (113), Expect = 9e-05 Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHWPIGL 434 A+K + + ++R DIFITTKL + + + + Q + SLK YIDLYL+HWP Sbjct: 62 ALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGAT 121 Query: 435 NADYSHSDVDFM--ETWRGLEDAQRMG*LKA 521 + ++ + +TW L D ++ G +++ Sbjct: 122 RIPETSTNNPSLRAKTWNKLVDLKKQGFIRS 152 Score = 47.6 bits (108), Expect = 4e-04 Identities = 20/63 (31%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKE-GTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G ++ IG+SNF + L+ +L+ I P Q+E+H Q+E++++C +G+ + YS Sbjct: 148 GFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELIKYCNEKGIHIQAYSS 207 Query: 683 FGS 691 G+ Sbjct: 208 LGT 210 Score = 39.1 bits (87), Expect = 0.13 Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQL-RDVVMRAIDVGYRHFDTASVYET 240 V ++ +++G DMP IG GTY K + ++L VV +++VG+R DTA Y Sbjct: 5 VRNVCLSSGYDMPLIGFGTY---------KIQGRELVYQVVDESLNVGFRSIDTAVGYRN 55 Query: 241 EQEIG 255 E++IG Sbjct: 56 EEDIG 60 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 49.6 bits (113), Expect = 9e-05 Identities = 17/48 (35%), Positives = 31/48 (64%) Frame = +3 Query: 282 GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 G V R+++F+ +K+WN H + +++ SL+ L LD++D +HWP Sbjct: 79 GGVDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWP 126 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/63 (33%), Positives = 36/63 (57%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G+V+ +G SN +L+ +L++ I P ++E+H Q E+ C G+ +GYSP Sbjct: 165 SGLVRHLGTSNTTVAKLDLLLRDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSP 224 Query: 683 FGS 691 GS Sbjct: 225 LGS 227 Score = 38.7 bits (86), Expect = 0.17 Identities = 21/65 (32%), Positives = 34/65 (52%) Frame = +1 Query: 64 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 243 VP ++ G +PAIG+GT+ G + ++ V A+ GYR D A+VY E Sbjct: 13 VPRRELRGGATVPAIGIGTF------GSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNE 66 Query: 244 QEIGK 258 ++G+ Sbjct: 67 AQVGE 71 >UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 682 Score = 49.6 bits (113), Expect = 9e-05 Identities = 28/71 (39%), Positives = 43/71 (60%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 452 +++ V R +++TTKL N H T V +A++ SL +LG+DY+DLYLM Sbjct: 469 VKDSGVSRSQVWVTTKLDNRWH--TRVQEALDMSLSELGMDYVDLYLM-----------L 515 Query: 453 SDVDFMETWRG 485 +D DF++TW G Sbjct: 516 ADWDFVKTWYG 526 Score = 37.1 bits (82), Expect = 0.52 Identities = 24/63 (38%), Positives = 32/63 (50%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S ++N G +PA+GLGT + G+V V A+ GYRH DTA E E Sbjct: 413 SFRLNTGALIPAVGLGTRRA-QKPGLVYR-------AVRSALKTGYRHIDTAMSSGVEHE 464 Query: 250 IGK 258 IG+ Sbjct: 465 IGQ 467 >UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 186 Score = 49.6 bits (113), Expect = 9e-05 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 4/82 (4%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IGLNADYSHS--- 455 V RE+IFIT+KLWNT + + + + +L LG+D +DLY + +N D + + Sbjct: 51 VPREEIFITSKLWNT--HQPNIKEGLQKTLDALGVDCLDLYNETSDLLPVNPDGTRAVDR 108 Query: 456 DVDFMETWRGLEDAQRMG*LKA 521 D ETWR +ED + G KA Sbjct: 109 SWDQSETWRQMEDFYKSGKAKA 130 >UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative; n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase (GCY1), putative - Aspergillus fumigatus (Sartorya fumigata) Length = 274 Score = 49.6 bits (113), Expect = 9e-05 Identities = 23/62 (37%), Positives = 37/62 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G VK IG++N++ LE + K+ T+ P Q+E+H Q + E+C G+++ YSP Sbjct: 120 GKVKAIGVANWSIPYLEELKKKWTVVPAVNQVELHPFLPQHALKEWCDKHGILLEAYSPL 179 Query: 686 GS 691 GS Sbjct: 180 GS 181 Score = 37.9 bits (84), Expect = 0.30 Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +1 Query: 58 MEVPS-LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 225 M +P+ K+N G +PAIGLGT+ +S+ Q+R V A+ GY H DTA Sbjct: 1 MALPTHFKLNTGAQIPAIGLGTW---------RSEPGQVRQAVSFALKNGYSHIDTA 48 >UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 279 Score = 49.6 bits (113), Expect = 9e-05 Identities = 20/48 (41%), Positives = 30/48 (62%) Frame = +3 Query: 288 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 431 V R+DIF+ TK+W + +V + +SL KLG+D +DL +HW G Sbjct: 69 VDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAG 116 Score = 39.5 bits (88), Expect = 0.097 Identities = 20/53 (37%), Positives = 28/53 (52%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 MP +GLGT+ D +Q + V A++ GYRH DTA Y+ E +G Sbjct: 17 MPMLGLGTWQNEDA--------EQCAESVRTALEAGYRHIDTAQAYDNESAVG 61 >UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismortui|Rep: Oxidoreductase - Haloarcula marismortui (Halobacterium marismortui) Length = 264 Score = 49.6 bits (113), Expect = 9e-05 Identities = 21/44 (47%), Positives = 29/44 (65%) Frame = +3 Query: 294 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 RED+F+T+K+ V +A SL +LG DY+DLYL+HWP Sbjct: 50 REDVFLTSKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWP 93 Score = 43.2 bits (97), Expect = 0.008 Identities = 21/61 (34%), Positives = 31/61 (50%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G ++ +G+SNF+ QL + QIE H N Q ++VEFC+ VV +P Sbjct: 113 GKIRNVGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAPL 172 Query: 686 G 688 G Sbjct: 173 G 173 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 49.2 bits (112), Expect = 1e-04 Identities = 20/61 (32%), Positives = 36/61 (59%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G ++ IGLSN++++ R+++ TI P +Q EVH+ N K+ F ++ G + + P Sbjct: 166 GKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVHIYNQDKQTKAFLRNYGTQMEAWYPL 225 Query: 686 G 688 G Sbjct: 226 G 226 Score = 48.4 bits (110), Expect = 2e-04 Identities = 24/57 (42%), Positives = 36/57 (63%) Frame = +3 Query: 255 EAVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 +AV + + + RE+IFITTK++ + A AIN+ L+ L DYIDL L+H+P Sbjct: 93 QAVGRAVRDSGIPREEIFITTKIYGSGDYANAEA-AINERLRLLDTDYIDLLLLHYP 148 Score = 40.3 bits (90), Expect = 0.056 Identities = 22/63 (34%), Positives = 33/63 (52%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++K+NNG +MP IG+G + +Q V A+ GYR DTA +Y EQ Sbjct: 44 TVKLNNGIEMPIIGIGVWT---------LTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94 Query: 250 IGK 258 +G+ Sbjct: 95 VGR 97 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 49.2 bits (112), Expect = 1e-04 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 7/90 (7%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLW-------NTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 419 +K ++ + R+D+F+T KLW + + + + SL +LGLDY+DLYL+H Sbjct: 94 IKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVDLYLIH 153 Query: 420 WPIGLNADYSHSDVDFMETWRGLEDAQRMG 509 P G D+ +E WR L + Q G Sbjct: 154 APYG-------GDMR-LEQWRALLELQANG 175 Score = 45.6 bits (103), Expect = 0.001 Identities = 20/60 (33%), Positives = 33/60 (55%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 679 ANG + IG+SNFN+ L + G PDA QIE+H + + +++ + + + YS Sbjct: 173 ANGKARSIGVSNFNESHLNEIKAAGLPMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYS 232 Score = 42.7 bits (96), Expect = 0.010 Identities = 23/67 (34%), Positives = 34/67 (50%) Frame = +1 Query: 55 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 234 T + +N +PA+G GTYL + + D + + AI GYRH DTAS Y Sbjct: 34 TNTATTFTLNTTTTIPAVGFGTYL-------ISNDDA--KSTISAAIQAGYRHIDTASGY 84 Query: 235 ETEQEIG 255 + E+ +G Sbjct: 85 QNEKTVG 91 >UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 293 Score = 49.2 bits (112), Expect = 1e-04 Identities = 22/63 (34%), Positives = 36/63 (57%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 ++K+ +G +P +G G Y +++ K+ D V +AID GYRH DTA Y E+ Sbjct: 8 TIKLASGNLIPRLGFGVY---------QARSKECEDAVKKAIDTGYRHVDTAQAYHNEEN 58 Query: 250 IGK 258 +G+ Sbjct: 59 VGR 61 Score = 40.3 bits (90), Expect = 0.056 Identities = 22/67 (32%), Positives = 35/67 (52%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 685 G VK IG+SNF L+ + P QIE+H Q+++V++C+ G+ + YSP Sbjct: 141 GWVKDIGVSNFGIHHLKALPPP---VPAVNQIELHPFCQQRDIVKYCEEHGIAIEAYSPL 197 Query: 686 GSLVARH 706 +H Sbjct: 198 VRANKKH 204 >UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 292 Score = 49.2 bits (112), Expect = 1e-04 Identities = 30/83 (36%), Positives = 45/83 (54%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 440 V + I E + RE +FITTK+ +V A++ SL++L LDY+DLYL+H P + Sbjct: 65 VGIAIRESGIPREQLFITTKVLEGWK---DVPGALDASLERLQLDYVDLYLLHNPYVI-- 119 Query: 441 DYSHSDVDFMETWRGLEDAQRMG 509 + D W+GLE + G Sbjct: 120 ---PNLTDIQSAWKGLEAVKATG 139 Score = 45.2 bits (102), Expect = 0.002 Identities = 20/66 (30%), Positives = 38/66 (57%) Frame = +1 Query: 58 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 237 M+ P+L + +G +P +G GT + ++ + +L +V+ A++ G+ H D A Y Sbjct: 1 MKWPALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYG 60 Query: 238 TEQEIG 255 TE+E+G Sbjct: 61 TEREVG 66 Score = 39.1 bits (87), Expect = 0.13 Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Frame = +2 Query: 500 ANGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH--LQNVQKEMVEFCQSEGVVVMG 673 A G + IG+SNF + LE +L+ ++ P Q+E H LQ + + + + G+ V Sbjct: 137 ATGKARSIGVSNFQRNHLEAILETCSVVPAINQLEYHPYLQR-SHDFIPWMRERGIEVSS 195 Query: 674 YSPFGSLVARHGSTVEGPRSTI 739 + + G ++ P ++I Sbjct: 196 FKTLAPVTVGKGGPLDEPLASI 217 >UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG07276.1 - Gibberella zeae PH-1 Length = 284 Score = 48.8 bits (111), Expect = 2e-04 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Frame = +2 Query: 491 RCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAI-QIEVHLQNVQKEMVEFCQSEGVVV 667 R + IG+SNF + L+ + + T P ++ QIE+H QKE+V++CQ +++ Sbjct: 136 RAKREARARNIGVSNFRVRHLDEMKEYATEWPPSVNQIELHPWCQQKEVVKYCQDNEIII 195 Query: 668 MGYSPFGSLVARHGSTVEG 724 YSP + VEG Sbjct: 196 EAYSPLATGARLEDPLVEG 214 Score = 46.0 bits (104), Expect = 0.001 Identities = 32/88 (36%), Positives = 51/88 (57%), Gaps = 5/88 (5%) Frame = +3 Query: 261 VKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL----GLD-YIDLYLMHWP 425 V+ IE+ V RED+F+TTK+ + R+TE +A D ++ + G D Y+DL LMH P Sbjct: 62 VREAIEQSGVFREDLFLTTKV-GSPRRKTEKTEAYEDVIEAVERIAGKDGYVDLLLMHVP 120 Query: 426 IGLNADYSHSDVDFMETWRGLEDAQRMG 509 G + ++ HS + ME + A+ +G Sbjct: 121 -GPSREHRHSLWEAMERAKREARARNIG 147 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 48.8 bits (111), Expect = 2e-04 Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +2 Query: 476 LARIGRCSANGIVKGIGLSNFNKQQLERVLKEGTIKPDAI---QIEVHLQNVQKEMVEFC 646 L + C G+ + IG+SNF + QL+ L + D I QIEVH KE+V +C Sbjct: 119 LKELKACKERGLTRHIGVSNFTQSQLDEALS--ILGKDHILTNQIEVHPNFQNKELVAYC 176 Query: 647 QSEGVVVMGYSPFG 688 Q + V Y P G Sbjct: 177 QRNNIQVTAYMPLG 190 Score = 47.2 bits (107), Expect = 5e-04 Identities = 18/51 (35%), Positives = 30/51 (58%) Frame = +3 Query: 273 IEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 425 I + R ++F+TTK+W + ++ +SL +L DY+DL L+HWP Sbjct: 57 ISASKISRGELFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP 107 Score = 42.3 bits (95), Expect = 0.014 Identities = 24/53 (45%), Positives = 29/53 (54%) Frame = +1 Query: 97 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 255 +P G GTY +K D +L V A+DVGYRH DTA YE E E+G Sbjct: 11 IPTPGFGTYR-------LKGDDAKL--AVENALDVGYRHIDTAQAYENEAEVG 54 >UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 275 Score = 48.8 bits (111), Expect = 2e-04 Identities = 32/88 (36%), Positives = 50/88 (56%) Frame = +3 Query: 258 AVKMKIEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 437 A+ +EE KREDI+ T+KL + ++ ++ +I+ S+K GL YIDL+L+H P G Sbjct: 59 AILKFMEETGTKREDIWFTSKLNDLSGYKSTLS-SIDASVKACGLGYIDLFLLHSPYG-- 115 Query: 438 ADYSHSDVDFMETWRGLEDAQRMG*LKA 521 D +E+W+ LE G L+A Sbjct: 116 --------DRIESWKALEKGVEEGKLRA 135 Score = 42.7 bits (96), Expect = 0.010 Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 1/60 (1%) Frame = +2 Query: 506 GIVKGIGLSNFNKQQLERVL-KEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 G ++ IG+SNF ++ +L I P QIE+H Q+++V++C+S+G+ + Y+P Sbjct: 131 GKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVVDYCESKGIQLAAYAP 190 Score = 36.7 bits (81), Expect = 0.69 Identities = 21/62 (33%), Positives = 32/62 (51%) Frame = +1 Query: 73 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 252 +K+NNG P G+Y+ V ++K D V A+ GYRH D+A +Y E + Sbjct: 6 VKLNNGLKCPQFAYGSYM------VNRTK---CFDSVYAALQCGYRHIDSAQMYHNEADC 56 Query: 253 GK 258 G+ Sbjct: 57 GR 58 >UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Os05g0456200 protein - Oryza sativa subsp. japonica (Rice) Length = 229 Score = 48.4 bits (110), Expect = 2e-04 Identities = 23/63 (36%), Positives = 38/63 (60%) Frame = +2 Query: 503 NGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 682 +G + IG+SNF+ ++LE +L + P Q+E H Q ++ + CQS+GV + Y+P Sbjct: 90 SGKARAIGVSNFSCKKLEDLLNVARVPPAVNQVECHPVWQQGKLRKLCQSKGVHLSAYAP 149 Query: 683 FGS 691 GS Sbjct: 150 LGS 152 Score = 35.5 bits (78), Expect = 1.6 Identities = 18/64 (28%), Positives = 32/64 (50%) Frame = +1 Query: 70 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 249 S +N +P++GLGT+ + ++D + A+ VGYRH D + Y ++E Sbjct: 4 SFVLNTNAAIPSVGLGTW---------QISPGAVQDAIRAAVQVGYRHIDCSPQYGNQKE 54 Query: 250 IGKP 261 + P Sbjct: 55 VHGP 58 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 879,882,333 Number of Sequences: 1657284 Number of extensions: 19068987 Number of successful extensions: 60061 Number of sequences better than 10.0: 479 Number of HSP's better than 10.0 without gapping: 56193 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 59701 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 69554636255 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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