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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdV10657X
         (572 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s...   125   6e-28
UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   122   5e-27
UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;...   105   7e-22
UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC...    87   4e-16
UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen...    79   7e-14
UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla...    79   1e-13
UniRef50_Q4AFR5 Cluster: Oxoglutarate dehydrogenase; n=1; Chloro...    77   4e-13
UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    76   7e-13
UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    75   2e-12
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    74   2e-12
UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1; Dictyo...    73   4e-12
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    73   5e-12
UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n...    72   1e-11
UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    71   1e-11
UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    71   1e-11
UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase doma...    71   1e-11
UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E...    71   2e-11
UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte...    70   3e-11
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    69   6e-11
UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n...    69   6e-11
UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1...    69   8e-11
UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    69   8e-11
UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    68   1e-10
UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;...    68   1e-10
UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    68   1e-10
UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    68   2e-10
UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    67   2e-10
UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E...    66   4e-10
UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    66   4e-10
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    66   4e-10
UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    66   6e-10
UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p - ...    66   6e-10
UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;...    66   6e-10
UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase,...    66   7e-10
UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus lu...    66   7e-10
UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ...    65   1e-09
UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3; ...    65   1e-09
UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    64   2e-09
UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p...    64   2e-09
UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome s...    64   2e-09
UniRef50_Q50992 Cluster: SucA protein; n=3; Neisseria|Rep: SucA ...    64   2e-09
UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    64   3e-09
UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni...    64   3e-09
UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1; Bdello...    63   4e-09
UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    63   4e-09
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr...    63   5e-09
UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;...    63   5e-09
UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    63   5e-09
UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000...    62   7e-09
UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 compone...    62   7e-09
UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    62   7e-09
UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who...    62   9e-09
UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica...    61   2e-08
UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    61   2e-08
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ...    61   2e-08
UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    60   3e-08
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    60   4e-08
UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    60   4e-08
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni...    60   5e-08
UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    59   6e-08
UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    56   4e-07
UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone...    56   4e-07
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    56   6e-07
UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura...    56   8e-07
UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    55   1e-06
UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    55   1e-06
UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    54   2e-06
UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    50   3e-05
UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, wh...    50   3e-05
UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;...    49   9e-05
UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    48   1e-04
UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    48   2e-04
UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    47   4e-04
UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni...    44   0.003
UniRef50_Q4RF13 Cluster: Chromosome 14 SCAF15120, whole genome s...    38   0.22 
UniRef50_Q6Z0Q8 Cluster: Putative uncharacterized protein B1144B...    37   0.39 
UniRef50_A0DNP7 Cluster: Chromosome undetermined scaffold_58, wh...    36   0.89 
UniRef50_P20807 Cluster: Calpain-3; n=55; Euteleostomi|Rep: Calp...    34   2.1  
UniRef50_A2F1Q8 Cluster: Calreticulin family protein; n=1; Trich...    33   3.6  
UniRef50_A0GS77 Cluster: ParB-like nuclease; n=5; Burkholderia|R...    33   4.8  
UniRef50_Q70T29 Cluster: Carboxyl methyltransferase; n=2; Magnol...    33   4.8  
UniRef50_Q4FYC3 Cluster: Putative uncharacterized protein; n=2; ...    33   4.8  
UniRef50_Q5H9T9 Cluster: Uncharacterized protein C14orf155; n=4;...    33   4.8  
UniRef50_A1WYJ0 Cluster: Efflux transporter, RND family, MFP sub...    33   6.3  
UniRef50_UPI00006CC895 Cluster: hypothetical protein TTHERM_0028...    32   8.3  
UniRef50_Q5CPR3 Cluster: Ring finger domain containing protein; ...    32   8.3  
UniRef50_Q384L9 Cluster: Putative uncharacterized protein; n=1; ...    32   8.3  

>UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome
            shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17
            SCAF14563, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1054

 Score =  125 bits (302), Expect = 6e-28
 Identities = 51/82 (62%), Positives = 70/82 (85%)
 Frame = +1

Query: 1    IALPFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCS 180
            + LPFRKPLI+ TPKSLLRHP+ +SSFDD+  GT FKR+IP+EGPA ++P  V+++ FCS
Sbjct: 878  VLLPFRKPLIIFTPKSLLRHPDARSSFDDLTTGTKFKRLIPDEGPAGQDPARVKRVIFCS 937

Query: 181  GRVYYDLLKQRRDKGLEKDIAI 246
            G+VYYDL K+R+D+ LE+++AI
Sbjct: 938  GKVYYDLAKERKDQKLEREVAI 959



 Score = 78.2 bits (184), Expect = 1e-13
 Identities = 33/53 (62%), Positives = 41/53 (77%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQI 413
            EQISPFP+D V+ E  KY +A+LVW QEEHKNMG + Y+ PRF T+L N+K I
Sbjct: 963  EQISPFPFDLVRTEAEKYVDAELVWCQEEHKNMGYYDYVRPRFLTVLANRKPI 1015


>UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component,
            mitochondrial precursor; n=77; Eumetazoa|Rep:
            2-oxoglutarate dehydrogenase E1 component, mitochondrial
            precursor - Homo sapiens (Human)
          Length = 1002

 Score =  122 bits (295), Expect = 5e-27
 Identities = 51/82 (62%), Positives = 70/82 (85%)
 Frame = +1

Query: 1    IALPFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCS 180
            I LPFRKPLI+ TPKSLLRHPE +SSFD+M  GT+F+RVIPE+GPA++NP+NV++L FC+
Sbjct: 846  ILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCT 905

Query: 181  GRVYYDLLKQRRDKGLEKDIAI 246
            G+VYYDL ++R+ + +   +AI
Sbjct: 906  GKVYYDLTRERKARDMVGQVAI 927



 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 28/53 (52%), Positives = 38/53 (71%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQI 413
            EQ+SPFP+D +  E+ KYPNA+L W QEEHKN G + Y++PR RT +   K +
Sbjct: 931  EQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTISRAKPV 983


>UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein; n=1;
            Nasonia vitripennis|Rep: PREDICTED: hypothetical protein
            - Nasonia vitripennis
          Length = 1012

 Score =  105 bits (252), Expect = 7e-22
 Identities = 46/82 (56%), Positives = 66/82 (80%)
 Frame = +1

Query: 1    IALPFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCS 180
            I +PFRKPL++MTPKSLLRHP  +SSFD++  GT+F+ +IP++   +  P+ VRK+ FCS
Sbjct: 842  ILMPFRKPLVIMTPKSLLRHPLAQSSFDEIGPGTSFRPLIPDQ---AVKPEGVRKILFCS 898

Query: 181  GRVYYDLLKQRRDKGLEKDIAI 246
            G+VYY+L  +R++KGLE +IAI
Sbjct: 899  GKVYYELYAERKEKGLENEIAI 920



 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 20/42 (47%), Positives = 30/42 (71%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPR 380
            EQI PFPY  V  +++KYP  +++W QEEH+N G++ Y+  R
Sbjct: 924  EQICPFPYRLVAEQVSKYPKCKIMWLQEEHRNQGAYHYVRER 965


>UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC,
            isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar to
            CG33791-PC, isoform C - Apis mellifera
          Length = 980

 Score = 86.6 bits (205), Expect = 4e-16
 Identities = 42/82 (51%), Positives = 56/82 (68%)
 Frame = +1

Query: 1    IALPFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCS 180
            I +PFRKPL +MTPKSLLRHP   S F DM+ GT+FK ++ +       P N++K+  CS
Sbjct: 811  IHMPFRKPLCIMTPKSLLRHPMALSPFADMESGTSFKPILSD---PFVKPGNIQKVLMCS 867

Query: 181  GRVYYDLLKQRRDKGLEKDIAI 246
            GRV+YDL+ +R+ K L   IAI
Sbjct: 868  GRVFYDLVTERQGKQLVDKIAI 889



 Score = 59.3 bits (137), Expect = 6e-08
 Identities = 24/47 (51%), Positives = 31/47 (65%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLL 395
            EQ+ PFPY  +  E+ KYPNA+L+W QEEHKN G + Y+  R    L
Sbjct: 893  EQLCPFPYHLLAEEMKKYPNAKLMWLQEEHKNQGPYLYVRDRIALAL 939


>UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome
            shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
            chr13 scaffold_17, whole genome shotgun sequence - Vitis
            vinifera (Grape)
          Length = 973

 Score = 79.0 bits (186), Expect = 7e-14
 Identities = 42/88 (47%), Positives = 60/88 (68%), Gaps = 10/88 (11%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSS---FDDM-------KEGTNFKRVIPEEGPASENPQNVR 162
            FRKPLI+M+PK+LLRH +CKS+   FDD+       K+GT FKR+I ++   S   + +R
Sbjct: 786  FRKPLIVMSPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSSLEEGIR 845

Query: 163  KLAFCSGRVYYDLLKQRRDKGLEKDIAI 246
            +L  CSG+VYY+L +QR+ K    D+AI
Sbjct: 846  RLILCSGKVYYELDEQRK-KVKANDVAI 872



 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 26/51 (50%), Positives = 37/51 (72%)
 Frame = +3

Query: 246  C*TEQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQ 398
            C  EQ+ PFPYD  + E+ +YPNA++VW QEE  NMG+++YI PR  T ++
Sbjct: 873  CRVEQLCPFPYDLAQRELKRYPNAEIVWCQEEPMNMGAYNYILPRLCTAMK 923


>UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5;
            Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza sativa
            (Rice)
          Length = 1016

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 40/88 (45%), Positives = 61/88 (69%), Gaps = 10/88 (11%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSS---FDDM-------KEGTNFKRVIPEEGPASENPQNVR 162
            FRKPLI+M+PK+LLRH +CKS+   FDD+       K+GT FKR+I ++    +  + ++
Sbjct: 829  FRKPLIVMSPKNLLRHKDCKSNLSEFDDLAGHPGFDKQGTRFKRLIKDQNNHKDLEEGIK 888

Query: 163  KLAFCSGRVYYDLLKQRRDKGLEKDIAI 246
            +L  CSG+VYY+L ++RR K  + D+AI
Sbjct: 889  RLVLCSGKVYYELDEERRKKERD-DVAI 915



 Score = 72.5 bits (170), Expect = 6e-12
 Identities = 30/63 (47%), Positives = 42/63 (66%)
 Frame = +3

Query: 210  ETRQGTRKGHCYC*TEQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRT 389
            E R+  R     C  EQ+ PFPYD ++ E+ +YPNA++VW QEE  NMG++SYI PR  T
Sbjct: 904  ERRKKERDDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEPMNMGAYSYINPRLLT 963

Query: 390  LLQ 398
             ++
Sbjct: 964  AMR 966


>UniRef50_Q4AFR5 Cluster: Oxoglutarate dehydrogenase; n=1;
           Chlorobium phaeobacteroides BS1|Rep: Oxoglutarate
           dehydrogenase - Chlorobium phaeobacteroides BS1
          Length = 508

 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 37/68 (54%), Positives = 45/68 (66%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           PFRKPLI+ TPKSLLRHP C S   D   G  F  VI +    S NP+ V K+ FC+G++
Sbjct: 303 PFRKPLIVFTPKSLLRHPLCVSPVSDFTSG-KFNEVIDD---VSVNPEQVNKVVFCNGKL 358

Query: 190 YYDLLKQR 213
           YYDLL +R
Sbjct: 359 YYDLLAER 366



 Score = 46.0 bits (104), Expect = 6e-04
 Identities = 19/40 (47%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQL-VWSQEEHKNMGSWSYI 371
           EQ+ PFP +Q+ A  A+Y  A+  +W+QEE  NMG+W++I
Sbjct: 380 EQLYPFPLEQILAINARYKKAKTHIWTQEEPANMGAWNFI 419


>UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=8; Deltaproteobacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Geobacter sulfurreducens
          Length = 894

 Score = 75.8 bits (178), Expect = 7e-13
 Identities = 37/79 (46%), Positives = 54/79 (68%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           PFRKPL++ TPKSLLRHP C S  +++  G  F+ VIP   P ++ P+ +R+L  CSG++
Sbjct: 734 PFRKPLVVFTPKSLLRHPRCVSRLEELSGGW-FREVIP---PVAD-PEKIRRLLLCSGKI 788

Query: 190 YYDLLKQRRDKGLEKDIAI 246
           YY+LL +R ++    D AI
Sbjct: 789 YYELL-ERMERDAVADTAI 806



 Score = 40.7 bits (91), Expect = 0.024
 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTL 392
           EQ+ P   D ++  +A +  A  + W QEE +NMG+WS++ P    L
Sbjct: 810 EQLYPLRTDLLREAVAPFRGAGSIAWVQEEPRNMGAWSFLRPHLADL 856


>UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component;
            n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
            component - Azotobacter vinelandii
          Length = 943

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 40/79 (50%), Positives = 53/79 (67%)
 Frame = +1

Query: 10   PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
            P RKPL+ +TPKSLLRH    S+ +D+  G +F  V+PE    S +P+ V +L  CSG+V
Sbjct: 776  PLRKPLVALTPKSLLRHKSAISTLEDLALG-SFHPVLPEVD--SLDPKKVERLVLCSGKV 832

Query: 190  YYDLLKQRRDKGLEKDIAI 246
            YYDLL +R  +G E DIAI
Sbjct: 833  YYDLLDKRHAEGRE-DIAI 850



 Score = 39.1 bits (87), Expect = 0.072
 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQ 410
            EQ+ PFP +++   +A Y N + +VW QEE  N G+W   +   R +    K+
Sbjct: 854  EQLYPFPEEELAEVMAPYTNLKHVVWCQEEPMNQGAWYCSQHHMRRVASAHKK 906


>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Haemophilus influenzae
          Length = 935

 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 39/77 (50%), Positives = 55/77 (71%)
 Frame = +1

Query: 16  RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
           R+PLI ++PKSLLRHP   SS D++  GT F+ VI E      +P++V+++  CSG+VYY
Sbjct: 773 RRPLIAISPKSLLRHPLAVSSLDELINGT-FQTVIGEIDEL--DPKDVKRVVMCSGKVYY 829

Query: 196 DLLKQRRDKGLEKDIAI 246
           DLL+QRR    +KD+AI
Sbjct: 830 DLLEQRRANN-QKDVAI 845



 Score = 39.5 bits (88), Expect = 0.055
 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIR 416
            EQ+ PFP++ VK  +  Y +    VW QEE  N G+W   +  F + +    +++
Sbjct: 849  EQLYPFPHEDVKKALEPYAHVTDYVWCQEEPLNQGAWYCSKHNFESAIPESVKLK 903


>UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1;
           Dictyostelium discoideum AX4|Rep: Oxoglutarate
           dehydrogenase - Dictyostelium discoideum AX4
          Length = 900

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 33/78 (42%), Positives = 53/78 (67%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +RKPLI+  PK LLRHP C S+ ++M  GT+F+ V+ +    + N   ++++ FCSG+V+
Sbjct: 735 YRKPLIVAGPKVLLRHPNCFSTLNEMAPGTHFQTVLSDPDTIN-NASTIKRVIFCSGKVF 793

Query: 193 YDLLKQRRDKGLEKDIAI 246
           YDL ++R+ K    D+AI
Sbjct: 794 YDLQEERKAKNF-NDVAI 810



 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 26/55 (47%), Positives = 37/55 (67%), Gaps = 1/55 (1%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIR 416
           EQI+PFPY +++ EI +Y NA +  W QEE +N G WS++EPRF+       QI+
Sbjct: 814 EQIAPFPYQRIQEEINRYSNATKFAWVQEEQQNGGCWSFVEPRFKQRYPQTSQIK 868


>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=16; cellular organisms|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Robiginitalea biformata
           HTCC2501
          Length = 940

 Score = 72.9 bits (171), Expect = 5e-12
 Identities = 36/78 (46%), Positives = 53/78 (67%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           FRKPL++ TPKSLLRH +C S+ +++ EG  F+ VI + G    + + V+ L FC+G+ Y
Sbjct: 764 FRKPLVVFTPKSLLRHAKCVSTVEELAEG-RFQEVIDDAG---ASVKKVKSLVFCTGKFY 819

Query: 193 YDLLKQRRDKGLEKDIAI 246
           YDLL  R + G E D+A+
Sbjct: 820 YDLLAAREELGRE-DVAL 836



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 21/44 (47%), Positives = 31/44 (70%), Gaps = 1/44 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRF 383
           EQ+ P P  Q++  I KY +A+ LVW+QEE +NMG+WS++   F
Sbjct: 840 EQLFPLPVVQMEELIEKYSHAEDLVWAQEEPRNMGAWSHLMMHF 883


>UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4;
            Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 -
            Rhodopirellula baltica
          Length = 969

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 35/78 (44%), Positives = 54/78 (69%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
            +RKPLI++TPKSLLRH E  S  D + EG +F++++P+     E     ++L  C+G+VY
Sbjct: 805  WRKPLIVLTPKSLLRHAEVTSPLDVVAEG-SFRKILPDRKVPLE---GAKRLVLCTGKVY 860

Query: 193  YDLLKQRRDKGLEKDIAI 246
            YDLL++R D+ +E D+ I
Sbjct: 861  YDLLQERTDRNIE-DVPI 877



 Score = 33.1 bits (72), Expect = 4.8
 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPN-AQLVWSQEEHKNMGSWSYIEPRFRTLLQNQ----KQIRA 419
            EQ+ P   D++ A        +++ W QEE +NMG+W Y++ +    L  +    K  RA
Sbjct: 881  EQLYPLSPDEIFAAFEGLAEGSEIRWVQEEPENMGAWPYLKLKIGDELNKRFRFTKATRA 940

Query: 420  KSQS 431
            +S S
Sbjct: 941  ESAS 944


>UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Dichelobacter nodosus VCS1703A|Rep:
           2-oxoglutarate dehydrogenase, E1 component -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 917

 Score = 71.3 bits (167), Expect = 1e-11
 Identities = 37/77 (48%), Positives = 51/77 (66%)
 Frame = +1

Query: 16  RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
           R+PLI+MTPKSLLRH    S    +  GT F  V  +   A ENP+ VR++  CSG++YY
Sbjct: 756 RRPLIVMTPKSLLRHKLAISPITALTAGT-FVNVFDDA--AIENPEKVRRVILCSGKIYY 812

Query: 196 DLLKQRRDKGLEKDIAI 246
           DL ++RR++G E  IA+
Sbjct: 813 DLWQKRREQGDEHTIAL 829



 Score = 46.0 bits (104), Expect = 6e-04
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYI 371
           EQ+ PFP D +   +  Y  A+L+W QEE +N G+W Y+
Sbjct: 833 EQLYPFPADALALILKNYSAAELIWCQEEPRNQGAWRYL 871


>UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component
            family protein; n=1; Tetrahymena thermophila SB210|Rep:
            2-oxoglutarate dehydrogenase, E1 component family protein
            - Tetrahymena thermophila SB210
          Length = 992

 Score = 71.3 bits (167), Expect = 1e-11
 Identities = 26/51 (50%), Positives = 37/51 (72%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQNQK 407
            EQI+PFPY+ +++ I  Y NA+ +W QEEH+N G+W+YIEPR   +L   K
Sbjct: 900  EQIAPFPYEDIRSAIQNYKNAEFIWCQEEHENSGAWTYIEPRLEIILDELK 950



 Score = 58.8 bits (136), Expect = 8e-08
 Identities = 36/82 (43%), Positives = 50/82 (60%), Gaps = 4/82 (4%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRH-PECKS--SFDDMKEGTN-FKRVIPEEGPASENPQNVRKLAFCS 180
            FRKPLI  T K LLR  P C +   F +  +  N FK V+PE     E+ Q V+K+  CS
Sbjct: 817  FRKPLIAFTSKKLLRFKPACSNIKEFTEFTDNPNLFKNVVPETEKIVESSQ-VKKVVICS 875

Query: 181  GRVYYDLLKQRRDKGLEKDIAI 246
            G+VY+DL++ R++   + DIAI
Sbjct: 876  GQVYWDLVEYRQEH-KKNDIAI 896


>UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase
           domain-containing protein 1; n=39; Eumetazoa|Rep:
           Dehydrogenase E1 and transketolase domain-containing
           protein 1 - Homo sapiens (Human)
          Length = 919

 Score = 71.3 bits (167), Expect = 1e-11
 Identities = 38/79 (48%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           FRKPLI+ +PK LLR P   S+  +M  GT F  VI   G +S +P+ V+ L FCSG+ +
Sbjct: 757 FRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVI---GDSSVDPKKVKTLVFCSGKHF 813

Query: 193 YDLLKQRRDKGLEK-DIAI 246
           Y L+KQR   G +K D AI
Sbjct: 814 YSLVKQRESLGAKKHDFAI 832



 Score = 55.6 bits (128), Expect = 8e-07
 Identities = 22/48 (45%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLL 395
           E++ PFP D ++ E++KY + +  +WSQEE +NMG WS++ PRF   L
Sbjct: 836 EELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQL 883


>UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E1
           component, sucA; n=1; Candidatus Protochlamydia
           amoebophila UWE25|Rep: Probable 2-oxoglutarate
           dehydrogenase E1 component, sucA - Protochlamydia
           amoebophila (strain UWE25)
          Length = 890

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 34/76 (44%), Positives = 51/76 (67%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           F KPLI+ TPK LLR+P+C S+  +  +GT F+ +I +      NP  +++L  CSGR+Y
Sbjct: 728 FEKPLIVFTPKGLLRYPKCVSALHEFTQGT-FREIIDD---VFANPSEIKRLVLCSGRIY 783

Query: 193 YDLLKQRRDKGLEKDI 240
           YDLL + R+K  +K+I
Sbjct: 784 YDLLAE-REKLNQKEI 798



 Score = 48.8 bits (111), Expect = 9e-05
 Identities = 21/54 (38%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQI 413
           EQ+ P   +++K  I +YP+ Q +VW+QEE +NMG+WS++ P    L+ +  Q+
Sbjct: 804 EQLYPLHMEELKKLIFQYPHIQEVVWAQEEPQNMGAWSFMFPYLNELISSSIQL 857


>UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17;
            Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella
            fastidiosa
          Length = 967

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 32/77 (41%), Positives = 55/77 (71%)
 Frame = +1

Query: 16   RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
            RKPL++MTPKSLLRH    S+ D++  G  F+ +IP++   + +P++V+++  C+G+VYY
Sbjct: 798  RKPLVVMTPKSLLRHKLAVSTLDELANG-KFQHIIPDD---AADPKHVKRIVMCAGKVYY 853

Query: 196  DLLKQRRDKGLEKDIAI 246
            D+L + + K  + D+AI
Sbjct: 854  DIL-ENQQKRSQNDLAI 869



 Score = 41.5 bits (93), Expect = 0.014
 Identities = 19/64 (29%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQS 431
            EQ+ PFP   + +E+ ++  A  +VW QEE +N G+W  I+   + +L + +++    +S
Sbjct: 873  EQLYPFPRALLASELKRFNKATDVVWCQEEPQNQGAWYQIKHHLQAVLAHAQRLHYAGRS 932

Query: 432  KGGS 443
               S
Sbjct: 933  SSPS 936


>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
            n=3; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
            component - Salinibacter ruber (strain DSM 13855)
          Length = 1243

 Score = 69.3 bits (162), Expect = 6e-11
 Identities = 35/77 (45%), Positives = 48/77 (62%)
 Frame = +1

Query: 16   RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
            +KPLI+MTPKSLLRHP+C S+ +D+ EG   + +IP E     +P    +   CSG+VYY
Sbjct: 1077 KKPLIIMTPKSLLRHPKCVSTPEDLMEG-GVQEIIPAEA----DPAGTMRHILCSGKVYY 1131

Query: 196  DLLKQRRDKGLEKDIAI 246
            DL+    D     +IAI
Sbjct: 1132 DLVTALEDTDRRDEIAI 1148



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 24/48 (50%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLL 395
            EQ  PFP   ++ E+ +Y  A + VW QEE +NMG+WS++ PRF TLL
Sbjct: 1152 EQFYPFPESDLQEELERYAEADETVWVQEEPQNMGAWSFVSPRFETLL 1199


>UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1;
           Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate
           dehydrogenase E1 - Blastopirellula marina DSM 3645
          Length = 929

 Score = 69.3 bits (162), Expect = 6e-11
 Identities = 34/78 (43%), Positives = 53/78 (67%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +RKPL++ TPKSLLRHP   SS  ++ EG  FK ++P+E   + +P  VR++  C+G++Y
Sbjct: 767 WRKPLVIFTPKSLLRHPSAVSSLTELAEG-EFKPILPDE---TCDPAKVRRVLLCTGKLY 822

Query: 193 YDLLKQRRDKGLEKDIAI 246
           Y+L   R +  L+ D+AI
Sbjct: 823 YELDSYRNEHQLD-DVAI 839


>UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1
            component family protein; n=1; Tetrahymena thermophila
            SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component
            family protein - Tetrahymena thermophila SB210
          Length = 1054

 Score = 68.9 bits (161), Expect = 8e-11
 Identities = 24/60 (40%), Positives = 40/60 (66%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQSK 434
            EQ+SPFPY+ +K  + +Y NA+++W QEEH+N G W+++ PR R +L   ++   +   K
Sbjct: 960  EQLSPFPYEHLKVVLEEYKNAKIIWCQEEHENQGGWNFVRPRIRAVLDRLQEEGERKNGK 1019



 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%)
 Frame = +1

Query: 1    IALPFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASEN-PQNVRKLAFC 177
            I  PFRKPL+L   K LLR     SS  + ++GT F  +  E+ P   N P  ++K+  C
Sbjct: 875  IRRPFRKPLVLFNSKRLLRFAGATSSLKEFQQGTRFLDIYKEQYPQDINEPSKIKKVVLC 934

Query: 178  SGRVYYDLLKQRRD 219
            SG+VYYD+L++R++
Sbjct: 935  SGQVYYDILERRQE 948


>UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
            n=2; Cystobacterineae|Rep: 2-oxoglutarate dehydrogenase,
            E1 component - Myxococcus xanthus (strain DK 1622)
          Length = 963

 Score = 68.9 bits (161), Expect = 8e-11
 Identities = 37/79 (46%), Positives = 52/79 (65%)
 Frame = +1

Query: 10   PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
            P RKPL++M+PKSLLR PE  S  +++  GT F+ VI +      +P  V +L  CSG+V
Sbjct: 791  PVRKPLVIMSPKSLLRRPEATSKVEELATGT-FQEVILDR----VDPAGVTRLLLCSGKV 845

Query: 190  YYDLLKQRRDKGLEKDIAI 246
            YYDL+K  RD+  ++ IAI
Sbjct: 846  YYDLVK-ARDERKDESIAI 863



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPN-AQLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAK 422
            EQ+ PF  D +   IAK P  A+L+W QEE +N G+W ++ PR   L   Q + + K
Sbjct: 867  EQLYPFASDVLAGLIAKMPKLAELLWVQEEPRNAGAWHFMFPRLHDLASTQSKQQVK 923


>UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=2; Proteobacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 940

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 37/79 (46%), Positives = 51/79 (64%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           P+RKPL++MTPKSLLRH    SS D+   G  F+ VI E       P  V ++  C+G+V
Sbjct: 771 PYRKPLVVMTPKSLLRHRLSVSSLDEFCSGA-FRLVIGEVDDI--KPAMVNRVILCAGKV 827

Query: 190 YYDLLKQRRDKGLEKDIAI 246
           YYDLL+ RR++   +D+AI
Sbjct: 828 YYDLLQARREQ-KRQDVAI 845



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 21/52 (40%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYI-EPRFRTLLQNQ 404
            EQ+ PFP  Q++ E+ +Y  A ++VW QEE +N G+W  +  P    L +NQ
Sbjct: 849  EQLYPFPQQQLERELERYRKAREIVWCQEEPQNQGAWDQLHRPLQGCLSRNQ 900


>UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate
           decarboxylase - Lentisphaera araneosa HTCC2155
          Length = 913

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 33/78 (42%), Positives = 54/78 (69%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +R PLI+MTPKSLLRHP+  S   D+ +G  FK  I ++  + ++ + + +L  CSG++Y
Sbjct: 748 YRIPLIVMTPKSLLRHPKVVSPVSDLTKG-EFKETIDDD--SVKDAKKIERLILCSGKIY 804

Query: 193 YDLLKQRRDKGLEKDIAI 246
           Y+LL ++  +GLE ++AI
Sbjct: 805 YELLDEKEKQGLE-NVAI 821



 Score = 40.7 bits (91), Expect = 0.024
 Identities = 26/61 (42%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQI-RAKSQ 428
            EQ  P P DQ  A   KY + +   W QEE +NMG W Y+  R   L  + K I R KS 
Sbjct: 825  EQFYPTPKDQDTALHKKYGHCKDWYWVQEEPQNMGGWYYMRARLDHLRHDMKFISRKKSA 884

Query: 429  S 431
            S
Sbjct: 885  S 885


>UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Coxiella burnetii
          Length = 934

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 35/80 (43%), Positives = 53/80 (66%), Gaps = 1/80 (1%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           P+RKPL+++TPKS+LR+    SS +D+  G   K +IPE      +P+ + ++  CSG+V
Sbjct: 768 PYRKPLVVLTPKSVLRNKLAVSSLEDLARG-QLKLLIPE--IEKHDPKKITRVILCSGKV 824

Query: 190 YYDLLKQRRD-KGLEKDIAI 246
           YYDLL +RR+ KG    IA+
Sbjct: 825 YYDLLAKRREHKGKLNHIAM 844



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 24/37 (64%), Positives = 31/37 (83%), Gaps = 1/37 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSW 362
           EQ+ PFPYD++KAE+ KYPNA Q++W QEE KN G+W
Sbjct: 848 EQLYPFPYDELKAELEKYPNAKQVIWCQEEPKNQGAW 884


>UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
            n=12; root|Rep: 2-oxoglutarate dehydrogenase, E1
            component - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 963

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 33/78 (42%), Positives = 52/78 (66%), Gaps = 1/78 (1%)
 Frame = +1

Query: 16   RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPE-EGPASENPQNVRKLAFCSGRVY 192
            RKPL++MTPKSLLR+ +  S   +  +G+ F+ +IPE +    +    V+++  CSG+VY
Sbjct: 790  RKPLVIMTPKSLLRNKDATSPLSEFTKGS-FQTIIPENKEEIIKKADKVKRIIACSGKVY 848

Query: 193  YDLLKQRRDKGLEKDIAI 246
            YDL K+R +KG + D+ I
Sbjct: 849  YDLAKKREEKGAD-DVVI 865



 Score = 48.8 bits (111), Expect = 9e-05
 Identities = 19/41 (46%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPN-AQLVWSQEEHKNMGSWSYIE 374
           EQ+ PFP+    AE+ KYPN   LVW Q+E +N G+W +++
Sbjct: 869 EQLYPFPHKAFAAELKKYPNVTDLVWCQDEPQNQGAWFFVQ 909


>UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component;
            n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1
            component - Rickettsia felis (Rickettsia azadi)
          Length = 977

 Score = 67.3 bits (157), Expect = 2e-10
 Identities = 36/77 (46%), Positives = 46/77 (59%)
 Frame = +1

Query: 16   RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
            RKPLI+M+PKSLLRH    S  D++ E T F  V+ E      N  N+ K+  CSG+VYY
Sbjct: 813  RKPLIIMSPKSLLRHKYAVSKLDELGENTTFLPVLDEVNKVDTN--NITKVILCSGKVYY 870

Query: 196  DLLKQRRDKGLEKDIAI 246
            DL + R   G   +IAI
Sbjct: 871  DLFEMR---GNNSNIAI 884



 Score = 42.3 bits (95), Expect = 0.008
 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQ 398
            EQ+ PF    V + + KY   Q  +W QEE KNMG+W YI      +L+
Sbjct: 888  EQLYPFEKKLVASLLKKYNRTQEFIWCQEEPKNMGAWRYIVSHLNDVLK 936


>UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1
           component; n=7; Bacteria|Rep: 2-oxoglutarate
           dehydrogenase complex, E1 component - Azoarcus sp.
           (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 942

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 32/77 (41%), Positives = 53/77 (68%)
 Frame = +1

Query: 16  RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
           RKPL+++TPKSLLRH E  S+  ++++G  F+ VI E    + +P+ V+++  C G++YY
Sbjct: 775 RKPLVIITPKSLLRHKEATSTLAELEDG-KFRTVIGE--TEALDPKKVKRVVLCQGKLYY 831

Query: 196 DLLKQRRDKGLEKDIAI 246
           +LL  RR+  + KD A+
Sbjct: 832 ELLAYRRENNI-KDTAL 847



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 18/43 (41%), Positives = 29/43 (67%), Gaps = 1/43 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPR 380
           EQ+ PFP     A + ++PNA ++VW+QEE +N G+W ++  R
Sbjct: 851 EQLYPFPAAAFGAAVDQFPNAREVVWAQEEPRNQGAWYWLASR 893


>UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component,
            putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate
            dehydrogenase E1 component, putative - Leishmania major
          Length = 979

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 25/59 (42%), Positives = 43/59 (72%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQS 431
            E++SPFP  +V+  +A+Y  A+L+W+QEE KNMGSW+++EPR     + ++++R   +S
Sbjct: 895  EELSPFPVAEVQQLLAEYEKAELMWAQEEPKNMGSWAHVEPRIEDYTKGERELRYAGRS 953



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 47/79 (59%), Gaps = 1/79 (1%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEG-PASENPQNVRKLAFCSGRV 189
            FRK L++   K  LR P   S+ +++  G  F+ VIP+   PAS+     R+L  C+G++
Sbjct: 820  FRKALVIFFSKKYLRAPNV-STLEELTSG-EFQPVIPDLSVPASQ----ARRLVMCTGQI 873

Query: 190  YYDLLKQRRDKGLEKDIAI 246
            Y+ L K R  KG+ KD+A+
Sbjct: 874  YHYLNKYRETKGV-KDVAL 891


>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
            n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
            component - Brucella melitensis
          Length = 1004

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 31/80 (38%), Positives = 50/80 (62%), Gaps = 7/80 (8%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVI-------PEEGPASENPQNVRKLA 171
            FRKPLI+MTPKSLLRH    S+  ++   ++F R++        +EG   +    +R++ 
Sbjct: 829  FRKPLIMMTPKSLLRHKRAISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVV 888

Query: 172  FCSGRVYYDLLKQRRDKGLE 231
             CSG+VYYDL ++R  +G++
Sbjct: 889  LCSGKVYYDLYEEREKRGID 908



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 21/47 (44%), Positives = 34/47 (72%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLL 395
            EQ+ PFP   +  E++++ +A++VW QEE KNMG+WS+I+P    +L
Sbjct: 916  EQLYPFPAKALINELSRFRHAEMVWCQEEPKNMGAWSFIDPYLEWVL 962


>UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=13; Rickettsiales|Rep: 2-oxoglutarate dehydrogenase E1
           component - Anaplasma marginale (strain St. Maries)
          Length = 930

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 38/70 (54%), Positives = 44/70 (62%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           FRKPL++ TPKSLLRH    S   D  EG +F  VI E   A  NP  VR++  CSG+VY
Sbjct: 769 FRKPLVVFTPKSLLRHKMAVSKISDF-EG-HFIPVIGEV--ADINPSAVRRVVVCSGKVY 824

Query: 193 YDLLKQRRDK 222
           YDLL  R DK
Sbjct: 825 YDLLAARADK 834



 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPR 380
           EQ  PFP + +  E+AKY  A +VW QEEH NMG WS++  R
Sbjct: 843 EQYYPFPTELLANELAKYKKASVVWCQEEHFNMGGWSFVRDR 884


>UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p -
           Drosophila melanogaster (Fruit fly)
          Length = 919

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 25/51 (49%), Positives = 38/51 (74%), Gaps = 1/51 (1%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQ 404
           E + PFP  +++A++A+Y N Q  VWSQEEH+NMG+W+++ PRF  L+  Q
Sbjct: 835 ESLCPFPIQELQAQLAQYGNVQSFVWSQEEHRNMGAWTFVRPRFENLIGQQ 885



 Score = 63.3 bits (147), Expect = 4e-09
 Identities = 34/82 (41%), Positives = 49/82 (59%)
 Frame = +1

Query: 1   IALPFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCS 180
           +A  FRKPL+++ PK+LLR P   S+ +D + GT F  V+   G     P+ VRK+  CS
Sbjct: 754 LARNFRKPLVVVAPKTLLRLPAATSTHEDFQPGTLFHNVL---GDTIAKPEQVRKVILCS 810

Query: 181 GRVYYDLLKQRRDKGLEKDIAI 246
           G+ YY L ++ R+K    D AI
Sbjct: 811 GKHYYTLAEE-REKRQAYDTAI 831


>UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative; n=4;
            Paramecium tetraurelia|Rep: 2-oxoglutarate dehydrogenase,
            putative - Paramecium tetraurelia
          Length = 964

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 32/78 (41%), Positives = 46/78 (58%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
            FRKPLIL   K LL+  +  S      EGT F R+IP+     + P+ ++K+  C G+VY
Sbjct: 792  FRKPLILFNSKRLLKFSKATSDISLFLEGTRFHRLIPDTHEEIKAPKEIKKVVICYGQVY 851

Query: 193  YDLLKQRRDKGLEKDIAI 246
            YD+L Q+R +    D+AI
Sbjct: 852  YDIL-QKRQETKRNDVAI 868



 Score = 62.9 bits (146), Expect = 5e-09
 Identities = 26/57 (45%), Positives = 39/57 (68%), Gaps = 3/57 (5%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFR---TLLQNQKQIR 416
            EQ++PFPYD  +    +Y NA+ V+ QEEH+N G+W Y+EPR +   +LL  Q +I+
Sbjct: 872  EQLAPFPYDHFRVVAQQYENAEFVFCQEEHQNSGAWQYLEPRIQNVLSLLHQQSKIK 928


>UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase, E1
            subunit; n=3; cellular organisms|Rep: Predicted
            2-oxoglutarate dehydrogenase, E1 subunit - Ostreococcus
            tauri
          Length = 1210

 Score = 65.7 bits (153), Expect = 7e-10
 Identities = 25/45 (55%), Positives = 33/45 (73%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRT 389
            EQ+ PFP+D +   + +YPNA LVW+QEE KNMG W+Y+ PR  T
Sbjct: 1026 EQLFPFPHDALARRLQRYPNAHLVWAQEEPKNMGYWAYVAPRIAT 1070



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 33/90 (36%), Positives = 53/90 (58%), Gaps = 11/90 (12%)
 Frame = +1

Query: 10   PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASEN----------PQN- 156
            P  KPL+++TPK+LL H  C S   D    ++F+RVI  +G A ++          P N 
Sbjct: 935  PHTKPLVILTPKTLLHHKYCASKLMDFAPKSSFRRVI-ADGDAGDDVTRHESIPLKPANE 993

Query: 157  VRKLAFCSGRVYYDLLKQRRDKGLEKDIAI 246
            ++++  C+G++YY L +QR  K ++ DIAI
Sbjct: 994  IKRVVLCTGKMYYQLARQRLAKKID-DIAI 1022


>UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 730

 Score = 65.7 bits (153), Expect = 7e-10
 Identities = 27/55 (49%), Positives = 38/55 (69%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRA 419
           EQ+ PFP+D +   + +YPNA LVW+QEE KNMG WS++ PR  T  +   ++RA
Sbjct: 627 EQLFPFPHDALARRLQRYPNAHLVWAQEEPKNMGYWSFVAPRIAT-TERATRVRA 680



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 32/93 (34%), Positives = 54/93 (58%), Gaps = 11/93 (11%)
 Frame = +1

Query: 1   IALPFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASEN----------P 150
           I+ P  KPL+++TPK+LL H  C S   D    ++F+RVI  +G A ++          P
Sbjct: 533 ISSPHSKPLVVLTPKTLLHHKHCASKLMDFAPKSSFRRVI-ADGDAGDDVTRHENIPLKP 591

Query: 151 Q-NVRKLAFCSGRVYYDLLKQRRDKGLEKDIAI 246
              ++++  C+G++YY L +QR  K ++ D+AI
Sbjct: 592 NGEIKRVILCTGKIYYSLARQRAAKKID-DVAI 623


>UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1013

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 35/81 (43%), Positives = 51/81 (62%), Gaps = 3/81 (3%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTN--FKRVIPEEGPASEN-PQNVRKLAFCSG 183
            FRKPL++ TPK LLR+   + SF   KE +N  F R+ PE  P   N P+ + ++ FC+G
Sbjct: 840  FRKPLVIATPKYLLRY---EKSFSTAKEFSNDSFTRLYPEAFPDQINKPEKINRIVFCTG 896

Query: 184  RVYYDLLKQRRDKGLEKDIAI 246
            +VYY+L+  R    + KD+AI
Sbjct: 897  QVYYNLIASRESNNI-KDVAI 916



 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 23/43 (53%), Positives = 30/43 (69%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRF 383
            EQ+ PFP+D V  ++  YPNA+ +W QEE  NMG W+YI P F
Sbjct: 920  EQLHPFPFDLVAEQLQHYPNAKAIWCQEEPMNMGYWNYIYPYF 962


>UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3;
           Bilateria|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 911

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 31/78 (39%), Positives = 51/78 (65%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +RKPLI++ PK LLRHP+  S+ ++   GT ++ VI EE   S   Q ++K+ F SG+ +
Sbjct: 749 YRKPLIVVGPKILLRHPKAASTINEFGPGTTYQNVISEEHATSS--QKIKKVIFVSGKHW 806

Query: 193 YDLLKQRRDKGLEKDIAI 246
            ++ K R ++GL+  +AI
Sbjct: 807 INVEKARDERGLKDSVAI 824



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 24/48 (50%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLL 395
           E + PFP   ++A + KYP AQ  VWSQEE +N G+WS++ PRF   L
Sbjct: 828 EMLCPFPVVDLQAVLKKYPGAQDFVWSQEEPRNAGAWSFVRPRFENAL 875


>UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=11; Francisella tularensis|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Francisella tularensis
           subsp. tularensis (strain FSC 198)
          Length = 941

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 31/70 (44%), Positives = 46/70 (65%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           P RKPLI+MTPKSLLR+P   SS  ++ +G  F+ +I +    +     V KL  C+G+V
Sbjct: 779 PLRKPLIVMTPKSLLRNPMAVSSLQELSQG-KFEAIIDD---VNAKAAKVTKLILCNGKV 834

Query: 190 YYDLLKQRRD 219
           YYDL+ +++D
Sbjct: 835 YYDLMAKKQD 844



 Score = 40.3 bits (90), Expect = 0.031
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQS 431
            E++ PFP  Q+     KY N  ++VW QEE +N G+W  I      L+  ++++   ++ 
Sbjct: 855  EELYPFPQQQLAQIFTKYNNVNKVVWLQEEPENKGAWYNIRHFIEKLVDKKQELLCVARE 914

Query: 432  KGGS 443
            +  +
Sbjct: 915  RSST 918


>UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit,
            putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate
            dehydrogenase subunit, putative - Trypanosoma brucei
          Length = 1008

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 28/53 (52%), Positives = 37/53 (69%), Gaps = 4/53 (7%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKY----PNAQLVWSQEEHKNMGSWSYIEPRFRTLLQN 401
            EQ+SPFP++QV   + KY    PN Q  W QEE KNMGSW+Y+ PR + LL++
Sbjct: 914  EQLSPFPWEQVADVLEKYHSRNPNVQFAWLQEEPKNMGSWAYVRPRLQRLLRH 966


>UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 13 SCAF15000, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 974

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 33/78 (42%), Positives = 50/78 (64%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
            FRKPLI++ PK+LLR     SS  +M  GT+F+ V+   G AS +  +V+++  CSG+ Y
Sbjct: 813  FRKPLIVVGPKTLLRFSGAVSSLAEMAPGTSFRPVL---GDASLSGDSVQRVVLCSGKHY 869

Query: 193  YDLLKQRRDKGLEKDIAI 246
            Y LLKQR     +++ A+
Sbjct: 870  YTLLKQRETSAAKQNTAL 887



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 23/48 (47%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLL 395
            E++ PFP + ++ E+ KYP A + VWSQEE +NMG W+++ PRF   L
Sbjct: 891  EELCPFPLEALQQELKKYPRATEFVWSQEEPQNMGPWTFVAPRFEKQL 938


>UniRef50_Q50992 Cluster: SucA protein; n=3; Neisseria|Rep: SucA
           protein - Neisseria gonorrhoeae
          Length = 582

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 27/54 (50%), Positives = 41/54 (75%), Gaps = 1/54 (1%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQI 413
           EQ+ PFPYD+VKAE+AKYPNA+ +VW+QEE KN G++  I  R   ++  ++++
Sbjct: 496 EQLYPFPYDEVKAELAKYPNAKSVVWAQEEPKNQGAFYQIRHRIEDVISEEQKL 549



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 29/78 (37%), Positives = 47/78 (60%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +RKPL++   K LLR     S  ++  EG+ F+ VI +    + N  +V+++  C+G+VY
Sbjct: 416 YRKPLVIFMSKRLLRFKGAMSPLENFTEGSTFRPVIGDTAERASN-DSVKRVVLCAGQVY 474

Query: 193 YDLLKQRRDKGLEKDIAI 246
           YDL   R ++ LE D+AI
Sbjct: 475 YDLEAGRAERKLEDDVAI 492


>UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
            n=15; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
            component - Deinococcus radiodurans
          Length = 956

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 34/95 (35%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
 Frame = +3

Query: 168  RILFRTRLLRSTQTETRQGTRKGHC---YC*TEQISPFPYDQVKAEIAKYPNAQLVWSQE 338
            R++  +  L    TE R+  ++G+        EQ+ PFP +QVKAE+AK+P AQ+VW+QE
Sbjct: 818  RVVLSSGKLHWELTEAREKDKEGYAGTALVRLEQLYPFPAEQVKAELAKHPGAQVVWAQE 877

Query: 339  EHKNMGSWSYIEPRFRTLLQNQKQIRAKSQSKGGS 443
            E +N G+W  I       LQ  + +   S+ +  S
Sbjct: 878  EPENQGAWLMIWEDLEHCLQPGQTLTHASRPRSAS 912



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 31/72 (43%), Positives = 45/72 (62%), Gaps = 1/72 (1%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           P+RKPLI+MTPKSLLR+    S   D+ +G  F  VI   G A    QN R++   SG++
Sbjct: 773 PYRKPLIVMTPKSLLRNKHAMSPLSDLYDGV-FHEVI---GDA--EVQNARRVVLSSGKL 826

Query: 190 YYDLLKQR-RDK 222
           +++L + R +DK
Sbjct: 827 HWELTEAREKDK 838


>UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
           n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase,
           E1 subunit - Anaeromyxobacter sp. Fw109-5
          Length = 940

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 32/72 (44%), Positives = 45/72 (62%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           PFRKPL++M+PKSLLRHP+  S   D+     F+ VI +E   S +P    ++  CSG++
Sbjct: 764 PFRKPLVVMSPKSLLRHPQVVSPL-DLLARERFQPVIDDE---SADPTETTRVVLCSGKL 819

Query: 190 YYDLLKQRRDKG 225
           YYDL   R  +G
Sbjct: 820 YYDLAGARTAQG 831



 Score = 48.8 bits (111), Expect = 9e-05
 Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +3

Query: 213  TRQGTRKGHCYC*TEQISPFPYDQVKAEIAKY-PNAQLVWSQEEHKNMGSWSYIEPRFRT 389
            T QG R        EQ+ P   + V+A IA+  P  ++VW+QEE  NMG+W Y+      
Sbjct: 828  TAQGARHA-AIVRLEQLYPLDVESVRASIARLRPGVEIVWAQEEPSNMGAWDYVNAHLAP 886

Query: 390  LLQNQKQIRAKSQS 431
             L ++  + A++ S
Sbjct: 887  RLPSRVALVARAPS 900


>UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1;
           Bdellovibrio bacteriovorus|Rep: Oxoglutarate
           dehydrogenase - Bdellovibrio bacteriovorus
          Length = 901

 Score = 63.3 bits (147), Expect = 4e-09
 Identities = 32/78 (41%), Positives = 54/78 (69%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           FRKPL++M+PKSLLRHP   SS +D+ +G  F+ VI +    + +   V  + F SG++Y
Sbjct: 737 FRKPLVVMSPKSLLRHPRAVSSIEDLAKG-RFQEVIAD----TIDKSKVDTVVFVSGKLY 791

Query: 193 YDLLKQRRDKGLEKDIAI 246
           Y+LL++ R+K  ++++A+
Sbjct: 792 YELLEE-REKSKKENVAL 808



 Score = 45.6 bits (103), Expect = 8e-04
 Identities = 22/44 (50%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRF 383
           EQI PFP  QV   +  YP A+ LVW+QEE KNMG++  +  +F
Sbjct: 812 EQIYPFPATQVTEVLKSYPKAKTLVWAQEEPKNMGAFQNVYFKF 855


>UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 component;
            n=8; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
            component - Geobacillus kaustophilus
          Length = 950

 Score = 63.3 bits (147), Expect = 4e-09
 Identities = 28/47 (59%), Positives = 35/47 (74%), Gaps = 1/47 (2%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTL 392
            E++ PFP + VK  IA+YPN  +LVW QEE KNMG+W Y+EPR R L
Sbjct: 862  EELYPFPEEAVKDIIARYPNVKELVWVQEEPKNMGAWLYMEPRLRAL 908



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 24/64 (37%), Positives = 38/64 (59%)
 Frame = +1

Query: 19  KPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYYD 198
           +PLI+MTPKSLLRHP   S  +   +G  F  V+ + G  ++    V ++ F +G++  D
Sbjct: 785 RPLIIMTPKSLLRHPLAASDAEVFVDGA-FSPVLEQPGLGAD-AGKVERIVFGTGKLMID 842

Query: 199 LLKQ 210
           L +Q
Sbjct: 843 LAEQ 846


>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
           (Succinyl-transferring), E1 component; n=4;
           Bacteroidetes|Rep: Oxoglutarate dehydrogenase
           (Succinyl-transferring), E1 component - Cytophaga
           hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 946

 Score = 62.9 bits (146), Expect = 5e-09
 Identities = 33/78 (42%), Positives = 50/78 (64%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           FRKPLI M PKSLLRHP   S   +   G  F+ VI +   A+ + + V+++ FC+G+VY
Sbjct: 779 FRKPLINMAPKSLLRHPLVVSDLKEFTSG-RFQEVIDD---ANVDAKKVKRVLFCTGKVY 834

Query: 193 YDLLKQRRDKGLEKDIAI 246
           YDL +++++     D+AI
Sbjct: 835 YDLFEEQKN-AKRNDVAI 851



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
 Frame = +3

Query: 168  RILFRT-RLLRSTQTETRQGTRKGHCYC*TEQISPFPYDQVKAEIAKYPNAQLVWSQEEH 344
            R+LF T ++      E +   R        EQ+ P+P  Q+ A   KY  A+ VW QEE 
Sbjct: 825  RVLFCTGKVYYDLFEEQKNAKRNDVAIVRIEQLYPYPEKQMAAVFEKYKGAEYVWVQEEP 884

Query: 345  KNMGSWSYIEPRFRTLLQNQKQIRAKSQS 431
             NMG+W YI  R   +     ++ A+ ++
Sbjct: 885  YNMGAWGYILRRMYLMNNTGIEVIARDEA 913


>UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;
           Aspergillus|Rep: Contig An06c0020, complete genome -
           Aspergillus niger
          Length = 456

 Score = 62.9 bits (146), Expect = 5e-09
 Identities = 34/80 (42%), Positives = 49/80 (61%), Gaps = 2/80 (2%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPE--EGPASENPQNVRKLAFCSGR 186
           FRKPLI++  KSLLRHP  +S  ++  E   F+ ++PE   G      ++++++ FCSG+
Sbjct: 279 FRKPLIILFSKSLLRHPLARSDIEEFIETPYFQPLLPETQHGININKLEDIKRVIFCSGQ 338

Query: 187 VYYDLLKQRRDKGLEKDIAI 246
           VY  L K R   GL KD AI
Sbjct: 339 VYAALYKYRETHGL-KDTAI 357



 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 24/48 (50%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLL 395
           E++ PFP++QV+  +  YPNA  +VW QEE  N G+WSY+ PRF  +L
Sbjct: 361 EELHPFPWEQVRQNLDNYPNATDVVWCQEETLNGGAWSYVMPRFEVIL 408


>UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1
           component - Leptospira interrogans
          Length = 920

 Score = 62.9 bits (146), Expect = 5e-09
 Identities = 29/78 (37%), Positives = 52/78 (66%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +RKPL+++TPKSLLR P   S  +D+ +G  F+ ++ ++  +   P  + K+ F +G+VY
Sbjct: 757 YRKPLVIVTPKSLLRFPASLSPVEDILQGA-FREILIDD--SGSKPDKIEKVVFSAGKVY 813

Query: 193 YDLLKQRRDKGLEKDIAI 246
           YDL+K  +D+   K++A+
Sbjct: 814 YDLMKY-KDENKIKNVAL 830



 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQI 413
           EQI PFP  ++++ +  + NA Q VW QEE KN G+W ++  R   LL    ++
Sbjct: 834 EQIYPFPAKEIQSSLKTFKNAKQFVWCQEEPKNQGAWFFVRERIEELLPGNARL 887


>UniRef50_UPI0000DAE34D Cluster: hypothetical protein
           Rgryl_01000074; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000074 - Rickettsiella
           grylli
          Length = 929

 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 31/71 (43%), Positives = 46/71 (64%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           P+RKPLILMTPKSLLRH    S+   + EG  ++ VI +      +   ++++  CSG+V
Sbjct: 767 PYRKPLILMTPKSLLRHKLAVSTLQALSEG-QWQSVISD---FEVDANAIKRVVLCSGKV 822

Query: 190 YYDLLKQRRDK 222
           YYDL + RR++
Sbjct: 823 YYDLFEMRREQ 833



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = +3

Query: 216  RQGTRKGHCYC*TEQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTL 392
            R+  ++G      EQ+ PFP  ++KA +  + N   +VW QEE KN G+W +I+    + 
Sbjct: 831  REQKQQGVALIRIEQLYPFPDIELKAALKPFSNVNDIVWCQEESKNQGAWYWIQHHLISC 890

Query: 393  LQNQKQIRAKSQS 431
            L+  + +R   +S
Sbjct: 891  LEKNQHLRYVGRS 903


>UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 component;
           n=1; Gluconobacter oxydans|Rep: 2-Oxoglutarate
           dehydrogenase E1 component - Gluconobacter oxydans
           (Gluconobacter suboxydans)
          Length = 885

 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 35/82 (42%), Positives = 51/82 (62%)
 Frame = +1

Query: 1   IALPFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCS 180
           IA   RKPL++ TPKSLLR+ +  S  D+M   T F+ VI +  PA E+    R++  C+
Sbjct: 716 IARRCRKPLVVFTPKSLLRNKDAVSMLDEMGPHTRFQPVIAD--PAKED--GARRIILCT 771

Query: 181 GRVYYDLLKQRRDKGLEKDIAI 246
           G+VYYDL  +R  +  + D+AI
Sbjct: 772 GKVYYDLAAERTRQNRD-DVAI 792



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 18/49 (36%), Positives = 33/49 (67%), Gaps = 1/49 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQ 398
           EQ+ PFP+  +  ++A++P A Q++W QEE +N G+W +++ R    L+
Sbjct: 796 EQLYPFPHHALMEQLARHPEAEQVLWCQEEPQNNGAWIFVDRRIERALR 844


>UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component
           , putative; n=1; Babesia bovis|Rep: 2-oxoglutarate
           dehydrogenase E1 component , putative - Babesia bovis
          Length = 891

 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 26/48 (54%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLL 395
           EQ+ PFP   +K+E+ +YPN + LVW QEEH N G WSY+ PR  +LL
Sbjct: 801 EQLCPFPAGALKSELERYPNLKRLVWCQEEHANAGGWSYVSPRICSLL 848



 Score = 39.5 bits (88), Expect = 0.055
 Identities = 22/62 (35%), Positives = 33/62 (53%)
 Frame = +1

Query: 16  RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
           RKPLI+MT K LL+      + ++      F+ +IP    +  N   V  L  CSG+VY+
Sbjct: 725 RKPLIVMTGKKLLKLRGTYCNIEEFGPSYGFRPMIP---ASVSNEDAVDTLILCSGQVYF 781

Query: 196 DL 201
           D+
Sbjct: 782 DI 783


>UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole
            genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_5, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1002

 Score = 62.1 bits (144), Expect = 9e-09
 Identities = 28/70 (40%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGP-ASENPQNVRKLAFCSGRV 189
            FRKPLI MT K LLR    KS  ++  E   F ++  +  P   + P  ++++  CSG+V
Sbjct: 831  FRKPLIAMTSKKLLRLQAAKSKLNEFSEQARFSQIYDDPFPELIDEPSQIQRVILCSGQV 890

Query: 190  YYDLLKQRRD 219
            YYD+LK+R +
Sbjct: 891  YYDILKKREE 900



 Score = 59.3 bits (137), Expect = 6e-08
 Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 5/68 (7%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQN-----QKQIRA 419
            EQ++PFPY+ ++  I KY  A   W QEEH+N G W+++ PR ++++       Q+QI+ 
Sbjct: 912  EQLAPFPYEFLQTVIQKYKKAHFAWVQEEHQNYGPWTFVRPRIQSVISKTQGLIQQQIQY 971

Query: 420  KSQSKGGS 443
              +   GS
Sbjct: 972  IGRKPSGS 979


>UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans
            CaKGD1 2-oxoglutarate dehydrogenase; n=4; Ascomycota|Rep:
            Similar to CA3149|CaKGD1 Candida albicans CaKGD1
            2-oxoglutarate dehydrogenase - Debaryomyces hansenii
            (Yeast) (Torulaspora hansenii)
          Length = 997

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQS 431
            EQ+ PFP+ Q++  +  YP  + LVW QEE  NMGS+SY  PR  T+L+N ++ + KS  
Sbjct: 906  EQLHPFPFAQLRDALDSYPALEDLVWCQEEPLNMGSYSYSAPRIATVLENTEKHKDKSLR 965

Query: 432  KGGSWLSQLFGRDESPQSNAQETETVR 512
              G   S           N++E E ++
Sbjct: 966  YAGRDPSASVAAGTKAMHNSEEEEFLK 992



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 27/71 (38%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVI--PEEGPASENPQNVRKLAFCSGR 186
            FRKPL+L   K LLRHP  KS   +    ++F+ +I  PE G +    ++++++  CSG+
Sbjct: 824  FRKPLVLFFSKQLLRHPLAKSELSEFTGESHFQWIIEDPELGKSINAKEDIKRVILCSGQ 883

Query: 187  VYYDLLKQRRD 219
            V+  L K+R D
Sbjct: 884  VFTALHKKRAD 894


>UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=4; Enterobacteriaceae|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Buchnera aphidicola subsp.
           Schizaphis graminum
          Length = 923

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 31/65 (47%), Positives = 45/65 (69%)
 Frame = +1

Query: 19  KPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYYD 198
           KPLI++TPKSLLR+   +SS + +    NFK VI E     +N + V+++ FCSG++YYD
Sbjct: 760 KPLIVLTPKSLLRNNVARSSLEVLVN-ENFKNVINE---IDKNQKEVKRIIFCSGKIYYD 815

Query: 199 LLKQR 213
           LL+ R
Sbjct: 816 LLEYR 820



 Score = 45.6 bits (103), Expect = 8e-04
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQS 431
            EQ+ PFP D++   +  Y   Q  +W QEE  N G+W YI+    TLL     +   S+ 
Sbjct: 834  EQLYPFPKDEILTILKSYSYVQDFIWCQEEPHNQGAWFYIKDLLSTLLPLNSHLNYVSRP 893

Query: 432  KGGS 443
               S
Sbjct: 894  SAAS 897


>UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1;
            Actinomyces odontolyticus ATCC 17982|Rep: Putative
            uncharacterized protein - Actinomyces odontolyticus ATCC
            17982
          Length = 1304

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 31/70 (44%), Positives = 42/70 (60%)
 Frame = +1

Query: 16   RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
            RKPLI  TPK LLR     S  D+   G  F+ VI +   +  NP +V ++  CSGR+YY
Sbjct: 1145 RKPLIAFTPKQLLRLSAASSHLDEFTSGA-FQPVIGDS--SITNPSSVTRVLLCSGRLYY 1201

Query: 196  DLLKQRRDKG 225
            DL+K+R  +G
Sbjct: 1202 DLMKEREHRG 1211



 Score = 45.6 bits (103), Expect = 8e-04
 Identities = 16/39 (41%), Positives = 26/39 (66%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYI 371
            EQ+ P P  +V   +A+YPNA + W Q+E +N G+W ++
Sbjct: 1221 EQLYPLPEAEVAETLAQYPNASVTWVQDEPRNQGAWPHL 1259


>UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component,
            mitochondrial precursor; n=34; Fungi/Metazoa group|Rep:
            2-oxoglutarate dehydrogenase E1 component, mitochondrial
            precursor - Saccharomyces cerevisiae (Baker's yeast)
          Length = 1014

 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 25/49 (51%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQ 398
            EQ+ PFP+ Q++  +  YPN + +VW QEE  NMGSW+Y EPR  T L+
Sbjct: 922  EQLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLK 970



 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIP--EEGPASENPQNVRKLAFCSGR 186
            FRKPL L   K LLRHP  +SS  +  EG  F+ +I   E G +    +  ++L   SG+
Sbjct: 841  FRKPLALFFSKQLLRHPLARSSLSEFTEG-GFQWIIEDIEHGKSIGTKEETKRLVLLSGQ 899

Query: 187  VYYDLLKQRRDKG 225
            VY  L K+R   G
Sbjct: 900  VYTALHKRRESLG 912


>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Blochmannia floridanus
          Length = 970

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 30/66 (45%), Positives = 43/66 (65%)
 Frame = +1

Query: 16  RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
           RKPLI+++PKSLLRHP   +S +D   G +FK +I E        Q V K+  C+G++YY
Sbjct: 802 RKPLIIVSPKSLLRHPMVHASIEDFTYG-SFKAIISETNNNCILTQ-VNKIIICTGKIYY 859

Query: 196 DLLKQR 213
           DL+ +R
Sbjct: 860 DLVNKR 865



 Score = 43.2 bits (97), Expect = 0.004
 Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQN 401
            EQ+ PFP+  +K  +  Y + +  +W QEE +N G+W YI+  F   + N
Sbjct: 879  EQLYPFPHVDIKIILKPYLHVENFIWCQEEPQNQGAWYYIQLYFHKYIPN 928


>UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=5; Enterobacteriaceae|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Escherichia coli (strain
           UTI89 / UPEC)
          Length = 939

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 29/79 (36%), Positives = 46/79 (58%)
 Frame = +1

Query: 10  PFRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRV 189
           P RKPL++M  K LLR     S   +  +G  +K V+ +  P     Q V+++  CSG+V
Sbjct: 771 PMRKPLVIMMSKRLLRFKGAMSELSEFTDGA-YKPVVTD--PQLHQSQKVKRVILCSGQV 827

Query: 190 YYDLLKQRRDKGLEKDIAI 246
           YYD+L+ R+ +  E ++AI
Sbjct: 828 YYDVLEARKQRECEDEVAI 846



 Score = 40.3 bits (90), Expect = 0.031
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQN 401
           EQ+ PFP  ++   +A +PN  + +W QEE +N G+W  I      L  N
Sbjct: 850 EQLYPFPVAELNDVLASWPNCCEWIWLQEEPENQGAWRQIRHELAALKIN 899


>UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
            n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
            subunit - Solibacter usitatus (strain Ellin6076)
          Length = 1220

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 29/69 (42%), Positives = 41/69 (59%)
 Frame = +1

Query: 16   RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
            RKPL++ TPKSLLRH +  S+  D   G  F  ++   G A      V ++ FCSG++YY
Sbjct: 1040 RKPLVIFTPKSLLRHQKAVSTLHDFTTG-GFTEILSGAGVADNG--LVSRVVFCSGKIYY 1096

Query: 196  DLLKQRRDK 222
            DLL  R ++
Sbjct: 1097 DLLAAREER 1105



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 24/65 (36%), Positives = 42/65 (64%), Gaps = 2/65 (3%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKY-PNAQLVWSQEEHKNMGSWSYIEPRFRTLL-QNQKQIRAKSQ 428
            EQ+ PF  DQ +  +A+Y P A++VW+QEE +NMG+W +I    + +L  ++++IR   +
Sbjct: 1116 EQLYPFAADQARDILARYAPTAEVVWAQEEPRNMGAWRFIRECLQAVLDDSRREIRYVGR 1175

Query: 429  SKGGS 443
             +  S
Sbjct: 1176 PESAS 1180


>UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component,
            mitochondrial, putative; n=9; Plasmodium|Rep:
            2-oxoglutarate dehydrogenase E1 component, mitochondrial,
            putative - Plasmodium vivax
          Length = 1059

 Score = 59.3 bits (137), Expect = 6e-08
 Identities = 23/53 (43%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQ 410
            EQ+SPFP+ Q   ++ +YPN + ++W QEEH NMG W Y+  R    +Q  K+
Sbjct: 926  EQLSPFPFKQFMQDLQRYPNLRDVIWVQEEHMNMGPWFYVSRRIEAAIQQLKR 978



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASEN-PQNVRKLAFCSGRV 189
            FRKPLI +TPK +L+      + ++    T F   +PE+     N  ++++++  CSG+V
Sbjct: 845  FRKPLIAITPKKMLKMRMAFDTIENFLPPTEFLPYLPEQQEHKLNDKEHIKRIILCSGQV 904

Query: 190  YYDLLKQRRDKGLEKDIAIA 249
            YYDLL  R    + KD+AIA
Sbjct: 905  YYDLLNYREANEI-KDVAIA 923


>UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
            n=1; Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
            dehydrogenase, E1 component - Orientia tsutsugamushi
            (strain Boryong) (Rickettsia tsutsugamushi)
          Length = 963

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 30/76 (39%), Positives = 48/76 (63%)
 Frame = +1

Query: 19   KPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYYD 198
            KPLI+M+PKSLLRH    SS  D+   + F+ +I E  P+ +    ++K+  CSG+++YD
Sbjct: 792  KPLIVMSPKSLLRHKLVLSSLTDLGPQSYFQAIIDEIDPSIQG--KIKKVIICSGKLFYD 849

Query: 199  LLKQRRDKGLEKDIAI 246
            L  + R+K    ++AI
Sbjct: 850  LY-EFRNKNKIANVAI 864



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQ 410
            EQ  PFP + +   +AKY    +++W QEE +NMG+W++I+P    ++   K+
Sbjct: 868  EQYFPFPTESLSTILAKYSVCDEIIWCQEEPQNMGAWTFIKPYLEDIIDKAKK 920


>UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component,
            putative; n=2; Theileria|Rep: 2-oxoglutarate
            dehydrogenase e1 component, putative - Theileria parva
          Length = 1030

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 11/90 (12%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPE-----------EGPASENPQNV 159
            +RKP+I +T K LL+     S+ D+   GT F+R IP+           +     NP +V
Sbjct: 843  YRKPMICITGKKLLKLRSSFSTIDEYLTGTRFRRYIPDNLFTTGKQDLSKEEKPRNPDSV 902

Query: 160  RKLAFCSGRVYYDLLKQRRDKGLEKDIAIA 249
            +++  CSG++YYDLL+ R      K+I +A
Sbjct: 903  KRMIMCSGQIYYDLLEYRDSNEEWKNIPVA 932



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 18/49 (36%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQ 398
            E+I+PFP   +  ++ K+ N + LVW QEEH+N G + ++  R   +L+
Sbjct: 935  EEITPFPAQNILDDLKKFKNLETLVWCQEEHENSGCFYFLRERLNNVLK 983


>UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
            n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
            component - Corynebacterium glutamicum (Brevibacterium
            flavum)
          Length = 1257

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 30/77 (38%), Positives = 48/77 (62%)
 Frame = +1

Query: 16   RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
            ++PL++ TPKS+LR+    S+ +D  E T F+ VI +  P   +   V+K+   SG++YY
Sbjct: 1094 KRPLVIFTPKSMLRNKAAASAPEDFTEVTKFQSVIND--PNVADAAKVKKVMLVSGKLYY 1151

Query: 196  DLLKQRRDKGLEKDIAI 246
            +L K R++K    DIAI
Sbjct: 1152 ELAK-RKEKDGRDDIAI 1167



 Score = 42.3 bits (95), Expect = 0.008
 Identities = 17/59 (28%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQ 428
            E + P P++++   +A YPNA ++++ Q+E  N G W + +     L+ N  ++R  S+
Sbjct: 1171 EMLHPIPFNRISEALAGYPNAEEVLFVQDEPANQGPWPFYQEHLPELIPNMPKMRRVSR 1229


>UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura
           dioica|Rep: CG1544-PA-like protein - Oikopleura dioica
           (Tunicate)
          Length = 886

 Score = 55.6 bits (128), Expect = 8e-07
 Identities = 27/78 (34%), Positives = 50/78 (64%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +RKP  ++ PK+LLR PE +S+F +M   T+F+ VI +    S+N    +++   +G+ Y
Sbjct: 725 YRKPGAIVMPKTLLRLPESRSTFAEMGPNTSFQTVIDD---PSKN-MKAKRVVVTAGKHY 780

Query: 193 YDLLKQRRDKGLEKDIAI 246
           + L+ +R  +G++ D+AI
Sbjct: 781 FTLVNERAKRGMQNDVAI 798



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 20/43 (46%), Positives = 31/43 (72%), Gaps = 1/43 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNA-QLVWSQEEHKNMGSWSYIEPR 380
           EQ+ PFP  +++  +A+Y NA   V+SQEE +N G+WS+ +PR
Sbjct: 802 EQLVPFPAKEIQETLARYTNATSFVFSQEEPRNCGAWSFAKPR 844


>UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Neorickettsia sennetsu str.
           Miyayama|Rep: 2-oxoglutarate dehydrogenase, E1 component
           - Neorickettsia sennetsu (strain Miyayama)
          Length = 905

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 26/70 (37%), Positives = 44/70 (62%)
 Frame = +1

Query: 19  KPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYYD 198
           +PL++ TPKSLLRH    S  ++  EG +F+ VI +      + + + ++ FCSG+VYYD
Sbjct: 751 RPLVVFTPKSLLRHKMAVSKLEEFYEG-SFRPVISD---YCSDAKKIHRVIFCSGKVYYD 806

Query: 199 LLKQRRDKGL 228
           LL + + + +
Sbjct: 807 LLAELKSESI 816



 Score = 42.3 bits (95), Expect = 0.008
 Identities = 15/39 (38%), Positives = 26/39 (66%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKNMGSWSYI 371
           EQ+ P P  +++  +  Y +A+ +W QEE +NMG WS++
Sbjct: 822 EQLYPVPDREIREILDVYRDAEFIWCQEEPRNMGGWSFM 860


>UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Acidobacteria bacterium Ellin345|Rep:
           2-oxoglutarate dehydrogenase, E1 component -
           Acidobacteria bacterium (strain Ellin345)
          Length = 820

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 26/68 (38%), Positives = 42/68 (61%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +RKPL+  TPKS+LRHPE  S   D+ +  +F+ V+P+        QN  +L  C+G++ 
Sbjct: 659 WRKPLVCFTPKSMLRHPEAVSPLSDLTK-PHFETVVPD-----HEVQNAERLLLCTGKIG 712

Query: 193 YDLLKQRR 216
           ++L  +RR
Sbjct: 713 HELRMERR 720



 Score = 53.2 bits (122), Expect = 4e-06
 Identities = 22/48 (45%), Positives = 36/48 (75%), Gaps = 1/48 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLL 395
           +QI PFP ++++A +A++PNA+  VW QEE  NMG+ S++EPR   ++
Sbjct: 733 DQIYPFPENELEAALAQHPNARDFVWVQEEPANMGALSFVEPRLHRII 780


>UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=7; Chlamydiaceae|Rep: 2-oxoglutarate dehydrogenase E1
           component - Chlamydophila abortus
          Length = 908

 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 28/70 (40%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
 Frame = +1

Query: 22  PLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYYDL 201
           PL++ TPK LLRHPEC S  D+  E   F+ ++ +    +E   + +    CSG+VYYD 
Sbjct: 748 PLVIFTPKMLLRHPECISWIDEFTEPGGFRPILED----AEPNYDAKVFVLCSGKVYYDF 803

Query: 202 ---LKQRRDK 222
              L Q R K
Sbjct: 804 KGALPQERKK 813



 Score = 39.1 bits (87), Expect = 0.072
 Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYI----EPRFRTLLQNQKQIRA 419
            E + P   + + + I KYP  +  VW QEE +NMG++ YI    E  F   L    + R+
Sbjct: 821  ESLYPLHLEDLLSVIGKYPKVEHYVWLQEEPQNMGAYDYIFMATEEIFPKKLTCVSRPRS 880

Query: 420  KSQSKGGSWLSQ 455
             S + G + LSQ
Sbjct: 881  SSTATGSARLSQ 892


>UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 component
            family protein; n=1; Tetrahymena thermophila SB210|Rep:
            2-oxoglutarate dehydrogenase, E1 component family protein
            - Tetrahymena thermophila SB210
          Length = 1004

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 24/66 (36%), Positives = 38/66 (57%)
 Frame = +1

Query: 13   FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
            +RKPL+++ PK+L+RH   KS+F+DM E T FK +I       E     + +   +G+  
Sbjct: 833  YRKPLVVVGPKTLIRHQLAKSTFEDMGEQTRFKEIIQR----LEVNHKTKNIIIMTGKFQ 888

Query: 193  YDLLKQ 210
            YD+  Q
Sbjct: 889  YDVYNQ 894



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYP--NAQLVWSQEEHKNMGSWSYIEPRFRTLLQNQK 407
            E++ PFP +Q+K  +AK    +A + W QEEH N G++ Y EP    +++  K
Sbjct: 910  EELLPFPEEQLKTILAKADAHHANIYWVQEEHINSGAYVYSEPHIARIIRELK 962


>UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_10,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 893

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 27/70 (38%), Positives = 41/70 (58%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           FRKPL++   KSLLR  + K +F+D+ E  +F+R+I  +    + P    K+ F  G+  
Sbjct: 727 FRKPLVIANAKSLLRSNKAKCTFEDLGEDKSFQRIITHK--QGDRP---NKVIFTYGKFV 781

Query: 193 YDLLKQRRDK 222
           YDLL+Q   K
Sbjct: 782 YDLLEQLEKK 791


>UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
           Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate
           decarboxylase - Plesiocystis pacifica SIR-1
          Length = 927

 Score = 48.8 bits (111), Expect = 9e-05
 Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
 Frame = +1

Query: 13  FRKPLILMTPKSLLR-HPECKSSFDDMKEGTNFKRVIPEEGPA--SENPQNVRKLAFCSG 183
           +RKPLILM+PKSLLR  P        +  G  FKRVI +E  A   E    V  +   +G
Sbjct: 755 WRKPLILMSPKSLLRFRPSFSPRERFLPGGGGFKRVISDEVTAGTKEAAAKVELVLVSAG 814

Query: 184 RVYYDLLKQRRDKGLEKDIAI 246
           +V+YD L+  R++   +D+A+
Sbjct: 815 KVHYD-LRAAREEHKREDVAL 834



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 22/45 (48%), Positives = 31/45 (68%), Gaps = 3/45 (6%)
 Frame = +3

Query: 255 EQISPFPY--DQVKAEIAKYPNAQLV-WSQEEHKNMGSWSYIEPR 380
           EQ+ PF    D +  +IA+YPNA+ + W QEE +NMG+W +I PR
Sbjct: 838 EQLYPFARTGDDLAEQIARYPNAKAIRWVQEEPRNMGAWLFIYPR 882


>UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=20; Bacillaceae|Rep: 2-oxoglutarate dehydrogenase E1
           component - Bacillus anthracis
          Length = 955

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 24/61 (39%), Positives = 39/61 (63%)
 Frame = +1

Query: 19  KPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYYD 198
           +PL+LMTPKSLLRHP   S+ + + EG  F+  + +E   ++ P  V++L   +G++  D
Sbjct: 773 RPLVLMTPKSLLRHPLTLSTANQLSEG-RFQPALEQENLGTK-PNKVKRLVLSTGKMAID 830

Query: 199 L 201
           L
Sbjct: 831 L 831



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 18/42 (42%), Positives = 31/42 (73%), Gaps = 1/42 (2%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEP 377
           EQ+ PFP ++V++ I ++ N + ++W QEE +NMG+W Y+ P
Sbjct: 853 EQLYPFPAEKVQSIIKRFKNLEEIIWVQEEPRNMGAWHYMAP 894


>UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
            n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
            2-oxoglutarate dehydrogenase E1 component - Buchnera
            aphidicola subsp. Cinara cedri
          Length = 933

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
 Frame = +3

Query: 255  EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQS 431
            EQ+ PFP+ ++   + KY N +  +WSQEE +N GSW +I   F+  + N  + + K Q 
Sbjct: 838  EQLYPFPFYKINKILNKYINIKYFIWSQEEPENQGSWKHIYFYFKKYIFNNNE-KKKLQY 896

Query: 432  KGGSWLS 452
             G S L+
Sbjct: 897  VGRSKLA 903



 Score = 39.5 bits (88), Expect = 0.055
 Identities = 22/63 (34%), Positives = 37/63 (58%)
 Frame = +1

Query: 16  RKPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYY 195
           + PLI+ TPKSLLRHP    S   +      K ++ ++   S +   + ++ FC+G++YY
Sbjct: 761 KTPLIIFTPKSLLRHPLTFISIKKLFIEKFHKILLFKKKNISLD--LISRVIFCNGKIYY 818

Query: 196 DLL 204
           +LL
Sbjct: 819 ELL 821


>UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Staphylococcus aureus
          Length = 932

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 19/51 (37%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQLV-WSQEEHKNMGSWSYIEPRFRTLLQNQ 404
           E++ PFP ++++A +A+ P  + V W QEE KN G+W Y+ P  + L+ ++
Sbjct: 845 ERLYPFPEEEIEALLAQLPKLEEVSWVQEEPKNQGAWLYVYPYVKVLVADK 895



 Score = 35.5 bits (78), Expect = 0.89
 Identities = 19/61 (31%), Positives = 33/61 (54%)
 Frame = +1

Query: 19  KPLILMTPKSLLRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVYYD 198
           +PL++M+PKSLLR+       D+   G  F+ ++ E    S     V K+   +G+++ D
Sbjct: 772 RPLVVMSPKSLLRNKTVAKPIDEFTSG-GFEPILTE----SYQADKVTKVILATGKMFID 826

Query: 199 L 201
           L
Sbjct: 827 L 827


>UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
           n=2; Burkholderiaceae|Rep: 2-oxoglutarate dehydrogenase,
           E1 subunit - Burkholderia phymatum STM815
          Length = 891

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 25/78 (32%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
 Frame = +1

Query: 19  KPLILMTPKSLLRHPECKSS--FDDMKEGTNFKRVIPEEGPASENPQNVRKLAFCSGRVY 192
           +PL++M+PKS L H  C S     D  +G+ F  ++P+  P   +P+ V ++  CSG+++
Sbjct: 726 QPLVVMSPKSQL-HGNCASHSPLSDFIDGS-FNPILPD--PGIVDPRVVTRVVLCSGKLF 781

Query: 193 YDLLKQRRDKGLEKDIAI 246
           Y+ L++ RD+  +   A+
Sbjct: 782 YE-LQRARDESRDTSTAL 798



 Score = 43.2 bits (97), Expect = 0.004
 Identities = 16/55 (29%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = +3

Query: 255 EQISPFPYDQVKAEIAKYPNAQ-LVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIR 416
           EQ+ PFP+D + + ++ +   + +VW+QEE +N G+W ++      +L    ++R
Sbjct: 802 EQLYPFPHDALASLLSGFEKLEEVVWAQEEDRNQGAWRFVREALEQVLPRGSRLR 856


>UniRef50_Q4RF13 Cluster: Chromosome 14 SCAF15120, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 14 SCAF15120, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1935

 Score = 37.5 bits (83), Expect = 0.22
 Identities = 18/50 (36%), Positives = 27/50 (54%)
 Frame = +2

Query: 83  TT*RREPISRE*SPKKVQPPRTLRMYANSHSVPDASTTIYSNRDATRDSK 232
           +T R+  +S +  P+K QP   L     +H  P +S  I S+  ATRD+K
Sbjct: 676 STKRKRSVSSQAKPRKRQPASLLNQKLTNHGQPSSSQEISSSESATRDAK 725


>UniRef50_Q6Z0Q8 Cluster: Putative uncharacterized protein
           B1144B06.23; n=2; Oryza sativa|Rep: Putative
           uncharacterized protein B1144B06.23 - Oryza sativa
           subsp. japonica (Rice)
          Length = 343

 Score = 36.7 bits (81), Expect = 0.39
 Identities = 17/37 (45%), Positives = 21/37 (56%)
 Frame = +1

Query: 328 GARRSTRTWARGATSSRASAPSCRTRSRLGQSPNRRG 438
           G+ R  R W RG   S A+AP  R+ S    SP+RRG
Sbjct: 187 GSGRRPRRWRRGYGESEAAAPCSRSSSSSSSSPSRRG 223


>UniRef50_A0DNP7 Cluster: Chromosome undetermined scaffold_58, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_58,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 647

 Score = 35.5 bits (78), Expect = 0.89
 Identities = 17/48 (35%), Positives = 29/48 (60%)
 Frame = +3

Query: 363 SYIEPRFRTLLQNQKQIRAKSQSKGGSWLSQLFGRDESPQSNAQETET 506
           +Y E   + LLQ+  QI+ +S+SK  S   + F + +SP  N Q+T++
Sbjct: 75  TYTESEHKRLLQSLTQIKYQSESKFESQFQESFLKQQSPSINIQQTKS 122


>UniRef50_P20807 Cluster: Calpain-3; n=55; Euteleostomi|Rep:
           Calpain-3 - Homo sapiens (Human)
          Length = 821

 Score = 34.3 bits (75), Expect = 2.1
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
 Frame = +3

Query: 183 TRLLRSTQTETRQ--GTRKGHCYC*T--EQISPFPYDQVKAEIAKYPNAQLVWSQEEHKN 350
           TR +   Q ETR   G  +GH Y  T  +++ PF  ++VK    + P  Q+ W+      
Sbjct: 314 TRTIIPVQYETRMACGLVRGHAYSVTGLDEV-PFKGEKVKLVRLRNPWGQVEWNGSWSDR 372

Query: 351 MGSWSYIEPRFRTLLQNQ 404
              WS+++   +  LQ+Q
Sbjct: 373 WKDWSFVDKDEKARLQHQ 390


>UniRef50_A2F1Q8 Cluster: Calreticulin family protein; n=1;
           Trichomonas vaginalis G3|Rep: Calreticulin family
           protein - Trichomonas vaginalis G3
          Length = 451

 Score = 33.5 bits (73), Expect = 3.6
 Identities = 21/63 (33%), Positives = 31/63 (49%)
 Frame = +3

Query: 294 EIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQNQKQIRAKSQSKGGSWLSQLFGRDE 473
           E AK P     W ++E + +   S I+P    LL   K I+ K+  K   W   +FG+ E
Sbjct: 216 ETAKKPED---WDEDEPEFIPDPSKIDPPKGWLLNEPKTIQDKNAKKPDDWDEAVFGQWE 272

Query: 474 SPQ 482
           +PQ
Sbjct: 273 APQ 275


>UniRef50_A0GS77 Cluster: ParB-like nuclease; n=5; Burkholderia|Rep:
           ParB-like nuclease - Burkholderia phytofirmans PsJN
          Length = 740

 Score = 33.1 bits (72), Expect = 4.8
 Identities = 14/39 (35%), Positives = 24/39 (61%)
 Frame = +3

Query: 282 QVKAEIAKYPNAQLVWSQEEHKNMGSWSYIEPRFRTLLQ 398
           QV AEIA + +  LVW  E+    G++  I+P+ + L++
Sbjct: 367 QVNAEIAAFESRTLVWDTEQMAEAGAFVIIDPQGKLLIE 405


>UniRef50_Q70T29 Cluster: Carboxyl methyltransferase; n=2;
           Magnoliophyta|Rep: Carboxyl methyltransferase - Bixa
           orellana (Lipstick tree)
          Length = 375

 Score = 33.1 bits (72), Expect = 4.8
 Identities = 18/58 (31%), Positives = 29/58 (50%)
 Frame = +3

Query: 360 WSYIEPRFRTLLQNQKQIRAKSQSKGGSWLSQLFGRDESPQSNAQETETVRAPLAITV 533
           W     +F+T   N  +IR++    GG  +    G+DESP ++ QE   V   LA+ +
Sbjct: 190 WKAYLRQFQTDFANFLKIRSRENKPGGRMVLAFVGKDESPLASRQECCAVYNLLAMAL 247


>UniRef50_Q4FYC3 Cluster: Putative uncharacterized protein; n=2;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major strain Friedlin
          Length = 1513

 Score = 33.1 bits (72), Expect = 4.8
 Identities = 14/33 (42%), Positives = 21/33 (63%)
 Frame = +3

Query: 432 KGGSWLSQLFGRDESPQSNAQETETVRAPLAIT 530
           +GGSWL+QL  +DE  QS  QE   +  P+ ++
Sbjct: 733 EGGSWLAQLDAQDEVAQSEMQEDRELLPPVPLS 765


>UniRef50_Q5H9T9 Cluster: Uncharacterized protein C14orf155; n=4;
           Catarrhini|Rep: Uncharacterized protein C14orf155 - Homo
           sapiens (Human)
          Length = 837

 Score = 33.1 bits (72), Expect = 4.8
 Identities = 24/84 (28%), Positives = 37/84 (44%)
 Frame = +2

Query: 98  EPISRE*SPKKVQPPRTLRMYANSHSVPDASTTIYSNRDATRDSKRTLLLLD*ADLSVPV 277
           EP S E  P K+QPP      A +   P A  T    + +T ++         A+ SV V
Sbjct: 258 EPPSTEKFPAKIQPPLVEEATAKAEPRP-AEETHVQVQPSTEETPDAEAATAVAENSVKV 316

Query: 278 RPGEGRDREVPERSARVEPGGAQE 349
           +P    +  + E  A ++P  A+E
Sbjct: 317 QPPPAEEAPLVEFPAEIQPPSAEE 340


>UniRef50_A1WYJ0 Cluster: Efflux transporter, RND family, MFP
           subunit precursor; n=1; Halorhodospira halophila
           SL1|Rep: Efflux transporter, RND family, MFP subunit
           precursor - Halorhodospira halophila (strain DSM 244 /
           SL1) (Ectothiorhodospirahalophila (strain DSM 244 /
           SL1))
          Length = 362

 Score = 32.7 bits (71), Expect = 6.3
 Identities = 23/71 (32%), Positives = 33/71 (46%)
 Frame = +2

Query: 95  REPISRE*SPKKVQPPRTLRMYANSHSVPDASTTIYSNRDATRDSKRTLLLLD*ADLSVP 274
           R P+S   +P+ V     L + + S   PD  TT+   R   RD+ R+L L+   D    
Sbjct: 205 RLPVSESLAPR-VDSGTELILSSRSGLRPDLKTTVSDLRPGIRDATRSLQLIAEVDNPGG 263

Query: 275 VRPGEGRDREV 307
            RPG   + EV
Sbjct: 264 WRPGASAEAEV 274


>UniRef50_UPI00006CC895 Cluster: hypothetical protein TTHERM_00289480;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00289480 - Tetrahymena thermophila SB210
          Length = 2039

 Score = 32.3 bits (70), Expect = 8.3
 Identities = 17/38 (44%), Positives = 25/38 (65%)
 Frame = +3

Query: 381  FRTLLQNQKQIRAKSQSKGGSWLSQLFGRDESPQSNAQ 494
            F++L  NQK +R KSQSK GS++ QL  +   P+ N +
Sbjct: 1807 FQSLKTNQKFLRFKSQSK-GSFIQQLKNQKSIPEYNLE 1843


>UniRef50_Q5CPR3 Cluster: Ring finger domain containing protein;
           n=2; Cryptosporidium|Rep: Ring finger domain containing
           protein - Cryptosporidium parvum Iowa II
          Length = 657

 Score = 32.3 bits (70), Expect = 8.3
 Identities = 15/39 (38%), Positives = 23/39 (58%)
 Frame = +1

Query: 52  LRHPECKSSFDDMKEGTNFKRVIPEEGPASENPQNVRKL 168
           L   E +  FD+ ++ +  KR+I +EG   EN Q V+KL
Sbjct: 135 LLEEELREDFDEKEDISLIKRLIKKEGNEKENSQEVKKL 173


>UniRef50_Q384L9 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma brucei|Rep: Putative uncharacterized protein
           - Trypanosoma brucei
          Length = 544

 Score = 32.3 bits (70), Expect = 8.3
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = +3

Query: 174 LFRTRLLRSTQTETRQGTRKGHCYC*TEQISPFPYDQVKAEIAKYP--NAQLVWSQEEHK 347
           L  +  LR ++ E+ Q  RKG   C  +++SP    QV A + +Y   N++ V S   H 
Sbjct: 38  LVESYFLRPSRIESEQAKRKGLGSCNLDEVSPSLAKQVGAVVHRYQLLNSKYVPSSFAHS 97

Query: 348 NM 353
           N+
Sbjct: 98  NV 99


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 506,954,405
Number of Sequences: 1657284
Number of extensions: 9408663
Number of successful extensions: 31699
Number of sequences better than 10.0: 87
Number of HSP's better than 10.0 without gapping: 30500
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31593
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 39154548218
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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